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warc | 202143 | Vitamin D for immmunodeficiency BIOBENE® VITAMIN D Vegan is a valuable nutritional supplement developed by experts. Vitamin D contributes to the functional and health maintenance of the Immune system, as well as to preserve normal bones to maintain a normal muscle function to preserve normal teeth
This has been scientifically proven by the European Food Safety Authority.
The meaning of VITAMIN D The fat-soluble vitamin D occupies a special position among the vitamins, because it can be formed in humans by exposure to sunlight (UVB light!). Vitamin D regulates the calcium and phosphate metabolism and thereby promotes the mineralization and hardening of the bone and is also involved in many other metabolic processes in the body (such as muscle metabolism, infection control). Vitamin D comes in two forms, collectively referred to as calciferols. There is a distinction between the vegetable vitamin D2 (ergocalciferol) and the animal vitamin D3 (cholecalciferol). However, both forms of vitamin are equally effective (equivocal).2)
Research results in recent years have now shown the connection between vitamin D supply and the function of the immune system and provide evidence of a role of vitamin D for many essential metabolic processes to ensure a normal immune defense. Especially in winter, the body's own vitamin D synthesis comes to a virtual standstill. Vitamin D deficiency is a real problem in Europe, because by 50-70% of the population, the vitamin D blood level is lowered, since the UV-B radiation in the northern hemisphere is lowered from October to March.
Reference values for VITAMIN D Vitamin D is given in µ (micrograms) or in international units (IU). 1 µ corresponds to 40 IU or 1 IU = 0.025 µ. The European Food Safety Authority (EFSA) published in 2012 a new "Scientific Opinion" for the safe intake of vitamin D with maximum limits of 100 µ / day, which would be 4,000 IU for persons over 11 years, children under 11 years 50 µ / day 2,000 IU. US studies suggest a recommended intake of 1,500 to 2,000 IU for adults and seniors Vitamin D per day . The DGE (German Society for Nutrition e.V.) states as new D-A-CH reference value 20 µ vitamin D per day (that is 800 I.U.). 1) The trend is clearly towards higher vitamin D intake recommendations.
The special feature of
BIOBENE® VITAMIN D Vegan is the pure plant origin of vitamin D - ergocalciferol - from cane sugar. Capsule shell and contents contain no animal ingredients. Therefore BIOBENE® VITAMIN D Vegan is especially suitable for vegetarians and vegans. BIOBENE® VITAMIN D Vega n has been certified by the Vegan Society of Austria and is entitled to carry the European Vegan Label; also certified by the Vegan Society, UK. Ingredients:
Nutrition
Information
2 capsules
contain
RDA* Vitamin D:
(vegan quality)
50 µg
= (complies) 2.000 IE
100%
*% recommendend daily allowance (RDA) according to (EU) Nr. 1169/2011
PACK SIZE PRICE 2) 60 capsules 14,95€
Directions: Take 2 capsules daily as a supplement with a glass of liquid, preferably at or after a fatty meal for at least 3 months. Do not exceed the recommended daily amount. Dietary supplements are not a substitute for a balanced and varied diet. A balanced diet and a healthy lifestyle are important. If you have problems with swallowing you may also open the capsules and mix it with other food. Please note: BIOBENE® VITAMIN D Vegan is suitable for diabetics. BIOBENE® VITAMIN D Vegan free of sugar, lactose, fructose, gluten, iodine, milk components, preservatives and colorants.
References:
1) Deutsche Gesellschaft für Ernährung e.V.
www.dge.de; Urashima M. et al: Randomized trial of Vitamin D supplementation to prevent seasonal influenza A in schoolchildren. Am J Clin Nutr 2010;91:1255-60 (2010); Ernährungskommission der Deutschen Gesellschaft für Kinder- und Jugendmedizin (DGKJ) in Zusammenarbeit mit der ARGE Pädiatrische Endokrinologie (APE): Vitamin-D-Versorgung im Säuglings-, Kindes- und Jugendalter. www.dgkj.de; Institute of Medicine – Food and Nutrition Board (2010); Dietary Reference Intakes for Calcium and Vitamin D, www.iom.edu/vitamind; Report Release: 30.11.2010; Published online 2007 December 18. doi: 10.1210/jc.2007-2308PMCID: PMC2266966;2) Vitamin D Is as Effective as Vitamin D in Maintaining Circulating Concentrations of 25-Hydroxyvitamin DMichael F. Holick, et al, December 18, 2007
2) recommended sales price in euro incl. value-added tax | 4,553 | 2,287 | 8,803.395715 |
warc | 202143 | Magnesium is one of the most important trace elements required in our bodies. You will find this out when you read about pregnant women who get a lack of Magnesium at a crucial time in their pregnancy. It seems that it is a pure accident because their bodies just do not produce enough. Magnesium and Zinc are however found together in trace quantities in many different types of leafy vegetables, fruits, seeds and even herbal remedies. The problem is however that most of these things are highly processed and their potency is reduced by the commercial processes used to convert them into usable products.
Zinc belongs to a group of minerals called amino acids and is needed in the body’s biochemical reactions. Zinc plays an important role in the immune system as well as being an important part of a balanced diet. However, you will find that Zinc is highly toxic when taken internally because of its toxicity to the cells. To prevent this from happening, zinc supplements (preferably as organic forms) are recommended as part of a healthy balanced diet.
Vitamins like Zinc belong to a group of nutrients known as co-enzymes and are involved in many physiological reactions in our bodies. It is a complex hormone with a wide range of biochemical reactions in the body. However, because it is sensitive to heat, it cannot always travel through our blood stream to reach the required destinations. That is why you will often find multivitamin supplements that contain Magnesium or another magnesium-containing nutrient like Aspartate.
Magnesium is one of the three mandatory minerals (along with calcium and phosphorus) required by the human body. Although Magnesium is abundant in nature, its absorption rate in the body is slow and requires vitamin d supplements for optimal levels. There are different forms of Magnesium available in nature. They can be found in different salts or bases such as: salts of Magnesium sulfate, tetraglycine and hydrochloride salts. The most common forms of Magnesium found in nature are as follows:
Supplements containing Magnesium are recommended as part of a balanced diet and to keep the body in good condition. However, the types of Magnesium contained in supplements may vary. The one that is found in highest concentration in commercial preparations are the Aspartate salts of Magnesium. These are used for general body uses as well as supplements for a number of diseases. Magnesium sulfate is also included in supplements for a variety of conditions.
The fastest way to take magnesium supplements is through eating foods rich in magnesium content. A good example of such a food is whole grains. Whole grains such as brown rice and oats contain high levels of Magnesium. The faster your body uses Magnesium the more effective it is.
Other good sources of Magnesium include meat, fish, green leafy vegetables, eggs, whole grains and fruits like banana and oranges. It is best to take magnesium supplements on a regular basis, especially if one is experiencing symptoms of any vitamin deficiencies. Vitamin D and calcium are two other minerals that are usually found in fruits and vegetables.
When you eat a well-balanced diet rich in vitamins, minerals and proteins you should notice an improvement in your mental and physical functions. However, if you have any kind of deficiency, it is best to consult your doctor before taking any kind of supplements. You may not have sufficient amounts of Magnesium sulfate in your intestines, for instance, and could experience muscle cramps or numbness due to insufficient levels of Zinc together with Magnesium. In this case, it may be better to take magnesium along with Zinc. | 3,675 | 1,639 | 8,208.770592 |
warc | 202143 | Members of Culture, Criticism and Community participate in various artistic constellations in and outside of work. Such involvement may serve as platforms for future artistic research efforts. Until such artistic research projects become a reality, we will introduce here some of the general artistic activities we participate in.
An example is the jazz band called Constanza Bergen Jazz Project, where our research group member Øystein Kvinge plays the piano. The band and its repertoire is centred around the talented and emerging singer Constanza Giacomelli from Malaga, Spain. The repertoire is a mix of well known standard tunes from the American songbook, and an exquisite selection of French standard material. Both the American and French material is treated as jazz standards, which allow for spontaniety and innovation during performance.
The band has appeared at jazz clubs in Bergen and in the surrounding region. Coming up is a performance at Mæland Jazz Club on April 25th, 2019.
Current line up: Constanza Giacomelli – vocals Peter Sæverud – bass Jan Tore Ness- drums Bjørn Blomberg – sax Øystein Kvinge – piano
The band performs What a difference a day makes (Grever/Adams) at Dyveke’s Wine Cellar, October 2018
DiSko is an innovation project intending to innovate school concert practices produced and implemented nationally by Arts for Young Audiences Norway (AYAN) and regional partners in Norway. The project will innovate an established practice through research based innovation procedures in order to respond to challenges connected to school ownership and school integration. This research-based innovation work will be carried out over four years with a selection of schools and groups of musicians and producers from NCA within a budget of 7.4 mill NOK. The DiSko project will develop and try out alternative concert forms, which to a greater degree can be experienced and shared by pupils, teachers as well as musicians. Our research questions are:
How can dialogue based concert practices be produced in order to be integrated as meaningful and professional elements in school´s everyday life?
How can schools facilitate such integration in their work with teaching, learning and Bildung?
DiSko´s point of departure is that shared ownership emerges through equity-based relations, and our practical innovation processes will be grounded in this belief. From the practical iterations of concert productions, researchers will develop analysis and research reports, and parallel to the concert production activities, a continuous implementation and discussion will take place. An interactive website will be a central component in the communication between researchers, musicians, teachers and users, other interested persons and organizations.
Funding: Norwegian Research council (NFR)
Project owner: Arts for Young Audiences Norway (AYAN)
Research partner: CASE center, at Stord/Haugesund University College | 3,007 | 1,493 | 5,909.268587 |
warc | 202143 | MUMBAI • The coronavirus pandemic has hit women worldwide with job losses and closures of childcare centres. Yet a surprising bright spot is emerging: India’s US$200 billion (S$268.4 billion) technology services industry, where new rules are expected to provide female workers with a broad swathe of flexible work arrangements and fresh employment opportunities.
On the outskirts of New Delhi, Ms Teena Likhari, 45, quit her job running operations for the Indian back office of a Silicon Valley company in 2018 because of a family medical emergency. Looking to rejoin the workforce this year, she expected a market stunted by lockdowns.
Not only did the operations manager quickly land a job with Indian outsourcer WNS Global Services, but working from her home in the city of Gurgaon, she began overseeing a 100-member team in the city of Pune about 1,450km away.
Ms Likhari is one of the early beneficiaries of India’s decision to lift decades-old restrictions on remote work in back-office firms because of the pandemic. The tech services industry – one of the country’s most important financially – can now allow employees to shift from traditional offices to work-from-anywhere arrangements, permanently if needed.
Indian women, who have often had to sacrifice for their husbands’ careers or other commitments at home, have much to gain from the policy change. “Even a year ago, an operations leader working remotely would’ve been unimaginable,” said Ms Likhari.
India’s large numbers of English-speaking graduates and lower costs relative to the West have spawned a sprawling industry that is often called the world’s back office because of its global reach.
The broad outsourcing sector, which includes technology services in addition to business processes, employs about 4.5 million people. Foreign banks from Deutsche Bank to Barclays run centres handling everything from global payrolls to technology infrastructure maintenance for themselves and clients.
Such new norms are particularly significant in India. Social conventions that required a woman to move to her husband’s locations or stay with family in small towns, or simply be available inside the home to care for elders and children, have shut out millions of qualified female workers.
Greater flexibility and the opportunity to work from anywhere would give them choices they have never had before.
India’s old rules – originally designed to prevent misuse of leased telecom lines – had prevented permanent work from home arrangements in back offices. But the pandemic pushed the government to remove decades-old reporting obligations, such as those requiring companies to provide office network diagrams in order to get international communication circuit allocations. The changes opened the door for people to work from home on a long-term basis.
Companies like WNS, which caters to the likes of Virgin Atlantic Airways, Tesco and Avon Products, are envisaging a hybrid office and home model, satellite offices in small cities and a blend of full-time employees and gig workers.
“We’ll see work going to people rather than people going to work,” said Mr Keshav Murugesh, group chief executive officer of WNS which employs 43,000 workers globally, nearly 30,000 of them in India. “With flexible hours or selected work days, over 100 million Indian women with secondary degrees could potentially find employment,” he said.
Mumbai-headquartered Tata Consultancy, closing in on half a million workers, has committed to a strategy that by 2025, only 25 per cent of its workforce will be working inside an office at any one time.
“Given time and location flexibility, fewer women will quit after having children,” said chief operating officer N.G. Subramaniam of Tata Consultancy, Asia’s largest outsourcer with US$22 billion in annual revenue. “More women will stay in the workforce, more will reach senior leadership levels.”
Most of the back-office outsourcing centres are located in sprawling campuses within big cities like Bangalore or New Delhi. Barclays, for instance, has over 20,000 workers providing technology solutions globally and UBS Group has 6,000 employees, about a third of them in Mumbai alone. Deutsche Bank employs 11,500, nearly half of whom are in the neighbouring city of Pune. Most of these workers have been operating from home during the pandemic.
“There is so much talent in smaller cities that has been untapped so far,” said Deutsche Bank India head of human resources Madhavi Lall. “Flexible work arrangements would certainly bring that talent to the fore, especially women who find it difficult to migrate or shift their base.”
BLOOMBERG | 4,805 | 2,341 | 9,517.635626 |
warc | 202143 | Every day people get into real estate investing thinking that they will make a lot of money, but sadly they go into blindly because they aren’t familiar with how to do it right. If you are getting into this type of investing, and want to know the right way to invest, you should continue to the following article. Keep reading for great investing tips!
Marketing will be crucial to your success. Marketing is what generates your leads. Without solid leads, you are not going to find good deals on properties. Therefore, if something is not working in your investment plan, turn to your marketing strategy first to see what is going on and what can be adjusted.
Remember that real estate investing is all about the numbers. When you’re buying a home to live in, you may get emotional about the place, but there’s no room for that in investing. … | 868 | 503 | 1,456.445328 |
warc | 202143 | In a viewpoint printed within the
Lancet, main well being officers from around the globe say booster doses of the COVID-19 vaccine aren’t vital but.
“Present proof doesn’t … seem to indicate a necessity for enhancing within the normal inhabitants, by which [vaccine] efficacy in opposition to extreme illness stays excessive,” the authors write.
The well being authorities say some individuals, together with these with weakened immune methods, might have booster doses to intensify their safety in opposition to COVID-19, however that knowledge supporting the necessity to give the final inhabitants further doses aren’t convincing at this level.
The commentary included consultants from the U.S. Meals and Drug Administration (FDA) and the World Well being Group (WHO), in addition to main tutorial establishments around the globe. It heightens the continuing rigidity amongst public well being officers regarding if, and when, booster doses ought to be given. One problem surrounds the science—public well being authorities are nonetheless deciphering knowledge on infections and illness amongst vaccinated individuals to know what these imply for immunity. One other problem is the restricted provide of vaccines for many of the world. Earlier this summer time, the WHO requested for a moratorium on offering boosters, at the very least till the top of the yr, till extra individuals, particularly in decrease useful resource nations, can get vaccinated. The U.S.’s public well being leaders, nevertheless, led by the White Home, determined to roll out boosters starting Sept. 20, although such further doses haven’t been deemed protected or efficient but by the FDA.
[time-brightcove not-tgx=”true”]
Research present that safety in opposition to COVID-19, measured by the extent of antibodies generated by people who find themselves vaccinated, wanes after about six months. However that doesn’t imply these individuals are dramatically extra susceptible to illness, the authors say. “Reductions in neutralizing antibody titer don’t essentially predict reductions in vaccine efficacy over time, and reductions in vaccine efficacy in opposition to gentle illness don’t essentially predict reductions within the (usually increased) efficacy in opposition to extreme illness.” Even in opposition to the most recent, extra transmissible variants of SARS-CoV-2, together with Delta, present vaccines proceed to guard individuals from getting extreme COVID-19, these well being officers say. Whereas uncommon, research have reported breakthrough infections by which vaccinated individuals have examined optimistic for the virus
. Within the U.S., Facilities for Illness Management (CDC) knowledge present that between January and April 2020, round 10,000 breakthrough infections have been voluntarily reported by states amongst 101 million vaccinated individuals (a fee of 0.01%). A couple of quarter of these individuals skilled no signs and nearly all of those who did have been largely gentle and didn’t require hospitalization or vital care.
So why have some well being officers so strongly advocated booster pictures, together with the highest public well being leaders within the U.S.? In August, President Biden’s well being crew, which incorporates chief medical advisor Dr. Anthony Fauci, the heads of the Nationwide Institutes of Well being, the CDC and the FDA, introduced that the U.S. plans to begin distributing booster doses on Sept. 20 for anybody eight months out from their final vaccine dose. The announcement stunned many within the medical neighborhood, since any further dose must be licensed or permitted by the FDA first, after which really helpful by the CDC. Whereas each Pfizer-BioNTech and Moderna have submitted requests to the FDA to greenlight a booster, the company has not decided but. The company did, in August, authorize booster pictures for a restricted inhabitants of individuals with compromised immune methods. The FDA Vaccines and Associated Organic Merchandise Advisory Committee meets on Sept. 17 to debate the information submitted by Pfizer-BioNTech (an analogous assembly for Moderna, if it is going to happen, has not been scheduled but).
The White Home mentioned it made its determination to roll out booster pictures with a view to give states and different native well being departments time to organize for an additional large vaccination marketing campaign—“to remain forward of this virus by being ready,” Surgeon Basic Dr. Vivek Murthy mentioned throughout a briefing on Aug. 18. The crew additionally mentioned knowledge regarding breakthrough infections amongst vaccinated individuals have been regarding, and pointed within the course of waning immunity.
However the
Lancet authors be aware that deciphering these knowledge might be difficult. For instance, much-cited analysis from Israel exhibits dropping ranges of immunity and better charges of breakthrough infections in latest months. Nevertheless, that analysis exhibits breakthrough infections have been increased amongst individuals vaccinated in January and April than these vaccinated in February and March, which doesn’t appear to observe any apparent scientific rationale.
Even when a booster does is required, the authors say {that a} extra focused vaccine in opposition to particular variants is perhaps simpler than including an extra dose of the present vaccine.
The authors additionally argue that utilizing restricted provides of present vaccines around the globe to first vaccinate the unvaccinated would do extra to scale back scale back the emergence of recent variants and lift total immunity charges than would boosting the already vaccinated. Though present vaccines could not assist individuals keep away from getting contaminated to start with, they proceed to supply satisfactory safety in opposition to extreme illness. Earlier than boosters are rolled out, they are saying, extra knowledge are wanted to justify which sorts of doses are simplest, once they is perhaps wanted, and for whom.
“Any selections concerning the want for enhancing or timing of boosting ought to be based mostly on cautious analyses of adequately managed scientific or epidemiological knowledge, or each, indicating a persistent and significant discount in extreme illness,” write the authors, “together with proof about whether or not a particular boosting routine is prone to be protected and efficient in opposition to presently circulating variants.” | 6,611 | 2,916 | 14,657.103909 |
warc | 202143 | Cosmetic surgery of the asian face
Try out PMC Labs and tell us what you think. Learn More. The face-lift procedure rhytidectomy is increasingly popular in Asia. There is extensive literature on different techniques in Western patients. Cultural and anthropomorphologic differences between Asian and Caucasians require the adaptation of current techniques to obtain a satisfactory outcome for both the patient and the surgeon.
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Asian facial skeletal contouring procedures are performed frequently in Asia, especially in South Korea. These surgeries that decreases the width and sharp angularity of the cheek bones and jaw. These surgeries address facial characteristics that tend to be more prominent in individuals of North Eastern Asian descent. However, these procedures are not limited to Asians. Individuals of any ethnicity who would like to modify their wide angular cheek bones, wide and low-set jaw, and short and broad chin, are all potential candidates for these procedures. This procedure decreases the sharp outward contour of your cheekbones.
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This has been largely led by the cosmetic surgery boom in South Korea, where 13 in 1, population has had some form of cosmetic procedure done, the highest per capita in the world, according to a survey led by the International Society of Aesthetic Plastic Surgeons. It is necessary to define the scope of discussion in this chapter, as there exists broad ethnic diversity within the Asian continent, which houses a population of 4 billion. The discussion in this chapter therefore excludes South Asians, Middle Easterners, and other Asians with Caucasoid features. This chapter focuses on the most commonly requested surgery for Asians—blepharoplasty—as well as facial bone contouring surgery, which is a surgery that is unique to the Asian population.
E-mail: gmaclinic gmail. It is mainly a procedurally oriented text with particular focus on common East Asian aesthetic surgical procedures. The Introduction explores the contemporary concepts of beauty among East Asians, namely the people of China, Korea, and Japan who form the target patients of this book. It points out that recent social and cultural changes brought about by rapid economic development in the area have contributed to a shift in conventional associations of beauty from Caucasian to Asian features. | 2,675 | 1,349 | 5,268.699036 |
warc | 202143 | The FDA adopted a regulation without notice or comment informing food producers of the maximum amount of unavoidable contaminants that it would permit. During court action to enforce a determination of condemnation of interstate food shipments as adulterated, the FDA has to prove that the foods were adulterated. D objected to the use of the FDA regulations to determine what was adulterated. FDA defended on the grounds that those regulations were exempted under section 533 as interpretative rules and general statements of policy. FDA claimed that action levels represented nothing more than nonbinding statements of agency enforcement policy. D argued that the action levels restrict enforcement discretion to such a degree that they are legislative rules. On the first time on appeal, the court concluded that the FDC Act, by stating that FDA 'shall promulgate regulations,' 21 U.S.C. § 346, required that FDA issue formal regulations or 'tolerances,' rather than informal action levels. The Supreme Court reversed that decision, holding that the FDC Act was not so clear as to preclude FDA's interpretation of the statute under which the agency could lawfully proceed by way of action levels. The Court did not reach the APA or blending issues and remanded the case for 'further proceedings consistent with [its] opinion.' The appeals court now addresses the issues of whether the action level violates the Administrative Procedure Act because it constitutes a legislative rule issued without the requisite notice-and-comment procedures, see 5 U.S.C. § 553; and if D's decision to permit adulterated corn to be blended with unadulterated corn to bring the total contamination within the action level violated the FDC Act. | 1,740 | 854 | 3,520.749415 |
warc | 202143 | Major crops are soybean, maize, sugarcane, and rice which account for 90% of total crop area, and (except for rice) the country is one of the largest producers and exporters of these crops.
Which is the major crop exported from Brazil? Coffee and soya bean are the major crops exported from Brazil. What are the 3 cash crops? Coffee, cocoa, tea, sugarcane, cotton, and spices are some examples of cash crops. Food crops such as rice, wheat, and corn are also grown as cash crops to meet the global food demand. Why is rice so expensive in Brazil?
The state’s production accounts for about 60 percent of the national rice crop. The high prices are
a result of limited supplies, as the weakened BRL makes exports more attractive, thus depleting domestic stock levels. What are Brazil’s major industries?
Industry. Brazil has advanced industries in the fields of
petroleum processing, automotive, cement, iron and steel production, chemical production, and aerospace. Why is Brazil’s agriculture so competitive?
However,
extended periods of currency depreciation, low energy costs and interest rates, rising demand for biofuel feedstocks, and macroeconomic fluctuations have contributed to Brazil’s emergence as a competitor for the United States in global agricultural markets. What are the 5 major foods produced in Brazil?
Major agricultural products are
coffee, sugar, soybeans, manioc, rice, maize, cotton, edible beans and wheat. Brazil produces about 20 billion litres of milk per annum and is the sixth or seventh largest world producer. How much money does Brazil make from sugar?
Sugar exports from Brazil amounted to
nearly nine billion U.S. dollars in 2020, an increase of 69 percent in comparison to the previous year. In terms of volume, exports of Brazilian sugar were forecast to reach in marketing year 2020/21 the highest figure recorded in at least 12 years. Which is the main occupation of Brazil? agriculture is their main occupation. What products are made in Brazil?
Other major manufactures include electrical machinery, paints, soaps, medicines, chemicals, aircraft, steel, food products, and paper. Brazil has been a major producer of
textiles, clothing, and footwear since the early 19th century. What are the 4 cash crops? Examples of cash crops grown in the United States today include: Wheat. Fruits and vegetables. Corn. Cotton. Sugar cane. Soybeans and oil-producing plants. Why are cash crops bad?
Cash crops
caused drastic effects to the environment. Poor soil quality, loss of forests, sediment build up in waterways, and the list goes on and on and on. | 2,622 | 1,297 | 5,225.805705 |
warc | 202143 | It can be very beneficial if you are going to use some residential wind turbines as your main source of electricity. As a matter of fact, there are already a lot of people who are into this practice and you might want to try it out too. This way, you will no longer have to think about your electric bills. This is also a good way for you to help save the planet because the energy that you are using is renewable.
However, there are still a lot of people who are hesitant about these residential wind turbines. They think that this task is very complicated and something that only the professionals can do. They are also worried about the materials because they do not know where they can find them.
But if you are going to learn more about these residential wind turbines, you will realize that all of your worries are actually just misconceptions. As a matter of fact, this is actually very simple because you just need to remember a few things.
There is just a need for you to plan things out very carefully so that you can accomplish this task successfully. You need to determine how much power you to produce, the appliances that you intend to power, and energy that you want to store, and a whole lot more.
But if you are really clueless about these kids of things, then it is recommended that you get your own guide. This way, you will be able to know the exact things that you will have to do so that you can pull this task off.
As for the materials, there are actually several hardware and specialty stores that sell these things. If you want, you can also get a kit that is complete with all the materials and tools that you are going to use. You just need to make sure that you are going to get something that is of good quality.
It is also much better if you are going to build your own residential wind turbines. If you are going to construct one, you are assured that you will be able to save more as compared to when you purchase a pre-made one.
And if you can make sure that you will be able to maintain these residential wind turbines, expect that this will be a lifetime investment.
Tired of high electric bills? Discover how thousands of families are using homemade Uk marriage visa solar power systems to power their homes! Also, read another popular article on Uk marriage visa DIY solar power system. | 2,333 | 1,027 | 5,277.077897 |
warc | 202143 | Some of the main issues that lawyer or attorneys and law firms face these days in regards to getting new clients is basically not knowing exactly how to do it properly. This causes them to chase after each shinny object or marketing person/company who promises all kinds of unreal results. However, the fact is that as a result of the increase in competition it becomes very expensive to really manage to maintain a consistent flow of new clients coming their way.
The main reason it has become more expensive is because everyone is fighting to be seen as number one in their respective area of law and geography. That is why, there are some things to consider when it relates to attempting to be seen as number 1 these days. To start with, it is necessary to bear in mind that nobody seeks out an attorney unless they need one. This means that traditional advertising methods will not produce a positive return on investment (ROI). That is because these methods based their strategy on creating the need or intending to take advantage of a need which may or may not exist on whoever is exposed to the information at a given time. Also, in order for these methods to be effective, they require a saturation of the marketplace, which means lots of advertising for a long period of time. This obviously costs a bunch of money and ROI will not be seen in the short term. | 1,370 | 731 | 2,561.956224 |
warc | 202143 | Published online by Cambridge University Press:
05 June 2012
Between 1980 and 2005 the absolute number of citizens of Latino origin in the United States nearly tripled from about 11 million to nearly 30 million. About 81% of this increase was because of births in the United States, and 19% was because of naturalization among the foreign-born. Yet, despite this increase in the actual number of citizens, the surge in migration to the United States from Latin America and the Caribbean after 1980 resulted in a declining percentage of all Latinos who were citizens from 80% in 1980 to 71% in 2005. This immigration resulted in a more than fourfold increase in the absolute number of Latinos who were not citizens of the United States from nearly 3 million in 1980 to over 12 million in 2005. If we consider the total citizen population of the United States, in 1980, about 5% were Latinos; by 2005 this percentage had increased to 11%.
The anti-immigrant sentiment, which has swept through the United States from the mid-1990s, exemplified by the passing of Proposition 187 in California in November 1994, led to a fairly significant increase in the yearly rate of naturalization among Latinos during the 1990s. There were over 1.2 million foreign-born naturalized Latino citizens in 1980 and over 4.7 million in 2005. Latino foreign-born residents who achieved citizenship through naturalization increased at about 5% annually during the 1980s, and this rate surged to 7% yearly between 1990 and 2000. However, between 2000 and 2005 the annual rate of naturalization increase among foreign-born Latinos fell to about 4% each year. | 1,637 | 757 | 3,529.173052 |
warc | 202143 | The side-event, ‘The CitiesIPCC Research and Action Agenda for effective urban responses to climate change’, will take place in the Pieniny Room at COP24 on 10 December 2018. It will be livestreamed, and a URL will be added to this page in the coming days.
The Research and Action Agenda is a primary output of the IPCC co-sponsored Cities and Climate Change science conference which took place in Edmonton, Canada, in March 2018. The Agenda presents key knowledge gaps jointly identified by the academic, practitioner and urban policy-making communities. It is intended to direct and stimulate knowledge generation that will underpin effective and efficient urban responses to climate change.
Speakers:
Debra Roberts, IPCC AR6 WGII Co-Chair (keynote speaker) Bill Peduto, Mayor of Pittsburgh Yann Françoise, City of Paris Shuaib Lwasa, Makerere University Valérie Masson-Delmotte, IPCC AR6 WGI Co-Chair Marcus Mayr, UN-Habitat Emmanuelle Pinault, C40
The event will be moderated by Seth Schultz of the Global Covenant of Mayors for Climate and Energy. | 1,078 | 637 | 1,780.307692 |
warc | 202143 | The Author ensures that the research has been conducted responsibly and ethically with adherence to all relevant regulations. read more..
Department of Public Health, Brigham Young University, Provo, USA
*Corresponding author: JamesDJohnston, Associate Professor, 2045 LifeSciences Building, Department of HealthScience, Brigham Young University, Provo,Utah, USA Submission: January 7, 2021; Published: January 27, 2021
The purpose of this pilot study was to characterize arrival and departure environments based on fine particulatematter (PM
2.5) air pollution concentrations at two elementary schools. Ambient PM 2.5 was measuredat the school front door, arrival/departure areas, street adjacent to the school, and in accompanyingplay fields (background). The overall average ratio of PM 2.5 to background at School-A (1.64) was lessthan at School-B (1.69) (t(35721)=2.52, p=0.01). PM 2.5 to background ratios were higher in the morning(1.80) than afternoon (1.43) (t(36434)=21.13, p<0.001). This study found a “plume” of PM 2.5 centered inthe arrival/departure location at both schools. For morning PM 2.5 measures, arrival/departure locationswere the highest at both schools, followed by front door, whereas, in the afternoon, street measures werethe highest. Solutions include encouraging idle-free zones, carpooling and encouraging active travel alonglow-traffic routes. Keywords: Particulate pollution; Fine particulate matter; School health; Children’s environmental health;Commuting exposure Abbreviations: PM 2.5 -Fine particulate matter
Ph.D in Agriculture from Faculty of Agriculture, Tohoku University
Wenzhou Medical University, China
Fooyin University, Taiwan
Saglik Bilimleri University, Turkey
Vincent Pol University, Poland
National Defence University of Malaysia, Malaysia
Dogus University, Turkey
Hope College, USA
Russian Academy of Sciences, Russia
Southern Cross University, Australia
Umm Al-Qura University, Saudi Arabia
City University of New York, USA
Khalifa University of Science & Technology, United Arab Emirates
Hebei Normal University, China
Alexandria University, Egypt
Indian Institute of Technology Kharagpur, India
Council for Agriculture Research and Analysis of Agri Economy (CREA), Italy
King Fahd University of Petroleum and Minerals, Saudi Arabia
King Abdulaziz University, Saudi Arabia
University of Oregon, USA
University of Edinburgh, Scotland
University of Tennessee, USA
Central University of Venezuela, Venezuela
Islamic Azad University Central Tehran Branch, Iran
Tourin University, Italy
Teaching & Public Speaking, Spain
Paeditric Hospital "Giovanni XXIII", Italy
University of Nicosia, Cyprus
Universidad Miguel Hernández de Elche, Spain
Oral Roberts University, USA
Beijing Normal University, China
Howard University, USA
Edith Cowan University, Australia
Dubai Health Authority, UAE
University of Minnesota, USA
Indian Institute of Technology Kharagpur, India
Serhal Hospital, Lebanon
University of Malta, Malta
National Center for Global Health and Medicine, Japan
Molloy College, USA
Federal University of Piauí, Brazil
Krankenhaus Nordwest Hospital, Germany
Laval University, Canada
Cinvestav-Unidad Saltillo, Mexico
UPMC Hamot Neuroscience Institute, USA
Ramon Llull University, Spain
White Bear Associates, LLC, USA
Lehigh University, USA
California Southern University, USA
Institute of Solid State Physics of RAS, Russia
University of Buenos Aires, Argentina
Mansoura University, Egypt
King Saud University, Saudi Arabia
University of Coimbra, Portugal | 3,599 | 1,735 | 7,285.122767 |
warc | 202143 | What is VPN?
A VPN service allows you to secure your site-to-site connections. A virtual private networking system extends a public network over a private one and allows users to transport and receive data over either public or private connections as if their personal computing devices were directly attached to the public network. As an example, you can connect to a VPN service so that you can make secure connections to banking sites, shopping sites, e-commerce sites, and other secure online services. All of these secure connections are possible because the connection is encrypted and protected.
There is a lot of misunderstanding when it comes to what is VPN and how people use them for what it actually is. Many assume that it is used just like a computer in that it allows you to use the Internet through another computer. While this is possible with a basic router, a VPN is much more comprehensive. In fact, it is often used to securely connect two or more independent network locations using the same Internet connection. This is often referred to as a VPN tunnel.
There are two main types of VPN. There is the Open VPN technology and then there is L2TP/IPsec VPN technology. The difference between them is the encryption. The former uses the encryption algorithm as the key. It also uses a random network layer that acts as an encryption key. On the other hand, the latter, L2TP/IPsec, uses a port-key instead as the encryption key but it also uses IP encryption.
Advantages and Disadvantages of VPN:
One of the advantages of VPN is that it provides complete privacy. Private communication is possible even between two individuals using a VPN. You can do this by using VPN services or connecting through a Wi-Fi hotspot. The encryption key is also used when you connect through a Wi-Fi hotspot. There is no need to key in your Wi-Fi network password because VPN does it all for you. This includes encryption and authentication.
Another advantage of a VPN is that it can provide a secure internet connection. As mentioned before, the encryption key is used when you connect to your internet service through a Wi-Fi hotspot. This way, you can make sure that your IP address cannot be tracked or blocked. With the use of a private VPN server, your internet connection will not be subject to any misuse by other users.
Pros and Cons of VPN Pros Bypass Geo-locked Content Provide Safety Through Anonymity Secure Connection for Remote Work Save Money on Region-Based eCommerce Cost-Effective Security Make Online Gaming Better Hides Your Online Identity VPN Can Prevent Bandwidth Throttling Can Bypass Firewalls Cons Slow Connection Speeds VPN Blocking Software Exists Complicated Set Up Dropped Connections Using the Wrong VPN Can Put Your Privacy in Danger Quality VPNs Will Cost Money
With VPN, you can be assured that you are accessing the internet without any threats. As long as you have an ideal internet connection and VPN, you can use the internet without exposing yourself to possible attacks. A VPN or virtual private network is one of the best ways to secure your data as well as your identity. However, choosing which among the numerous VPN services available is the cheapest option can be somewhat confusing. Here are some of the options that you can consider.
When it comes to VPN, the first option that you can consider is a free VPN service. Although you can enjoy the benefits of VPN with free VPN, the security that you can enjoy is quite limited. There is no encryption or authentication involved and what is more, free VPNs are prone to attacks from hackers and other internet threats. The encryption used in free VPNs is usually weak and it may also not be impossible for your IP address to be tracked.
Paid VPN is considered to be the best option for those who want ultimate security and what is VPN for you. The paid VPNs have strong encryption algorithms and strong authentication systems. You also get complete remote management, a secure VPN, and a number of other features. But even with the added features, paying for a paid what is VPN service provider will still prove to be beneficial. It helps you manage and secure your work even when you are on the move.
Is VPN Good or bad?
Using a VPN is actually a good idea specifically if you are using free WiFi. The VPN secures your WiFi connection by encrypting the connection to safeguard your internet usage and data privacy. You should not use Free VPN.
Is VPN legal?
yes, VPN is legal under US law and many other countries have given the legal status to VPN unlike countries like China where VPN is banned, this is a violation of human basic rights.
Should I pay for a VPN?
If I am being honest with you then investing in VPN is a good idea to secure your privacy and data sharing with big companies.
List of Best Paid VPNs:
Here are some of our recommended VPNs to use:
Express VPN Nord VPN Avast VPN AVG VPN
Hope you have got an idea about what is VPN and how does it work.
To check if your VPN is working properly or not you can check out this article on Whatleaks.
Elora is PR and Outreach Manager at Crunchoid Inc. Outside of work, Elora enjoys Flywheel, tacos, the tennis, and adventuring around the globe. | 5,224 | 2,347 | 11,574.265019 |
warc | 202143 | Wherever the corpse is, there the vultures will gather. Matthew 24:15-31 I remember while at Kruger National Park in South Africa we noticed a group of vultures quietly boldly resting on a dead tree. The guide told us that it was possible that there was a dead animal somewhere and they were waiting there turn to feast on whatever was left of its corpse. My first reaction was “how gross.” The reality however, is that’s what vultures do. In referring to the end times in this passage of Matthew, Jesus is merely stating the obvious. It’s also a warning – a message about following what is dead, namely false prophets who lead people astray. Today, that’s not the only dead thing in this world that leads people astray. We must be able to recognize who and what they are, lest we become more like vultures and less like enlightened disciples of Christ. “Where the corpse is, there the vultures will gather.” Luke 17:20-37 Traveling through Krueger National Park in South Africa gave me a different kind of appreciation for life and death. It was nothing like the Bush Gardens Animal Kingdom I visited as a child. In South Africa we rode in an open vehicle as we watched life in this kingdom around us. Up close I saw four of the “big five” animals and a host of other wildlife including a group of vultures perched on a dead tree. Jesus’ discourse about the Kingdom of God being among them and the condition of days when the Son of Man is revealed, ends with the disciples asking where all of this will happen? His response was simply; “Where the corpse is, there the vultures will gather.” Vultures are highly intelligent birds yet serve as natures janitor. They feast on what is dead and decaying. Although they are very important to the ecosystem, Jesus makes clear that what is dead has no place in the Kingdom of God. There are those whose purpose is to feast on what is dead and decaying. We are called to life but if we become like those in the days of Noah and the days of Sodom the “vultures” will gather around us as well. | 2,110 | 1,029 | 4,168.736638 |
warc | 202143 | What is Diabetes and What are the Causes of it.
Diabetes is a group of metabolic disorders leading to the person having high blood glucose (sugar), either because insulin production is inadequate, or because the body’s cells do not respond properly to insulin.
The main symptoms of Diabetes include:
Polydipsia (Excessive thirst) Polyphagia (Excessive Eating) Polyuria (Excessive Urination) Fatigue Weight Loss Blurred Vision Slow Wound Healing Genital Itching What is Type 1 and Type 2 Diabetes ?
Type 2 diabetes is the more common form of diabetes. This form occurs when the body produces enough insulin but is unable to use it effectively (insulin resistance). It is more widespread in people that are older, are overweight or obese, have a family history of diabetes, or have had gestational diabetes (when you are pregnant).
Is Diabetes Curable?
As a nutritionist I am not allowed to say that I can cure any disease! However, my experience tells me that the symptoms of Diabetes Type II can be reversed (traditional medicine would say that the disease has gone into remission) through diet and lifestyle modifications.
Diabetes and the Diet
The diet is one of the most important factors when it comes to diabetes, as it is a condition in which the blood sugar levels increase. Any diet that contains carbohydrates or sugars is directly responsible for increasing the blood sugar level. The following foods are responsible for the development and aggravation of type 2 diabetes so they should be avoided:
all foods that contain sugar such as jam, jelly, marmalade, chocolates, desserts, ice cream, confectionery, and so forth honey soft drinks and other artificially sweetened cold drinks milk and milk products such as cheese and butter fruits and fruit juices that have a high sugar content oily foods alcoholic beverages
Contrary to popular perception, there’s no diabetes diet. However, it’s important to center your diet on these high-fiber, low-fat foods:
Fruits Vegetables Whole grains
You’ll also need to eat fewer animal products, refined carbohydrates and sweets.
A nutritionist can help you put together a meal plan that fits your health goals, food preferences and lifestyle. Remember the importance of consistency. To keep your blood sugar on an even keel, try to eat the same amount of food with the same proportion of carbohydrates, proteins and fats at the same time every day.
Low glycemic index foods also may be helpful. The glycemic index is a measure of how quickly a food causes a rise in your blood sugar. Foods with a high glycemic index raise your blood sugar quickly. Low glycemic foods may help you achieve a more stable blood sugar. Foods with a low glycemic index typically are foods that are higher in fiber.
Diabetes and Exercise
Everyone needs regular aerobic exercise, and people who have type 2 diabetes are no exception. Get your doctor’s OK before you start an exercise program. Then choose activities you enjoy, such as walking, swimming or biking. What’s most important is making physical activity part of your daily routine. Aim for at least 30 minutes of aerobic exercise most days of the week. Stretching and strength training exercises are important, too. If you haven’t been active for a while, start slowly and build up gradually.
Remember that physical activity lowers blood sugar. Check your blood sugar level before any activity. You might need to eat a snack before exercising to help prevent low blood sugar if you take diabetes medications that lower your blood sugar.
Diabetes and Lifestyle
Type 2 diabetes is a lifestyle disease, and people that lead a sedentary lifestyle are more prone to suffering from it. This is because they have unexercised muscles and tissues, which can affect the overall action of insulin and reduce its capacity in the utilisation of glucose.
Stress is another important cause of type 2 diabetes as it can cause malfunctioning of the pancreas and thus affect the secretion of insulin. Some common stress factors include injury, surgery, infections, pregnancy, and mental tensions or worries.
Diabetes and Obesity
Obesity is a major cause of type 2 diabetes. This is because being overweight is linked to insulin resistance. If your body fat levels are higher than thirty percent, you have a BMI over 25, or a waist size more than 90cm for women and 100cm for men, you are at high risk.
For a free consultation with Emma Olliff, click here. First consultation is absolutely FREE. | 4,522 | 2,121 | 9,513.042904 |
warc | 202143 | The hard outer layer of your teeth, the enamel is incredibly strong and durable. However, it has some limitations. Some common causes of chipped teeth like falling down and impacting the mouth, chewing on ice, popcorn kernels on non-food items can chip your teeth. In addition, teeth weakened from decay are also susceptible to chipping. If you have a chipped tooth, you can visit a dental clinic offering emergency dental services to receive prompt treatment.
Chipped teeth are painful and need attention from a dental professional. Your teeth can sustain damages in several ways, and the damage can be minor or significant depending on the condition of your teeth and the type of injury. Unless you have a minor chip, do not think you can fix it without help from a dentist. However, you can address the pain you experience and protect your tooth beside the inside of your mouth to prevent further injuries.
It’s an excellent idea to call emergency dentistry soon after realizing you have chipped a tooth in your mouth. Meanwhile, there are some self-care measures you can take. Rinse your mouth with warm water right away to clean it is recommended by the American Dental Association. If the chipped tooth is bleeding, use a piece of sterile gauze over the bleeding area. Apply some pressure to stop the bleeding and use ice packs over your cheeks to control swelling.
You can flush the inside of your mouth with warm water and apply a cold compress to your cheeks every few minutes to keep the swelling down. In addition, over-the-counter pain relievers and anti-inflammatories can help you manage the discomfort from the chipped tooth. However, please do not exceed the recommended dosage and stay away from any painkillers that also act as blood thinners that might increase bleeding instead of preventing it.
Chipped teeth are not all similar, and you might have different types of chips. When you get to the emergency dental clinic near you, the dental professional will examine your teeth thoroughly. The dentist keeps you informed which type of chips affects you and the treatment best suited for your condition.
If you have chipped your molar of the lower jaw because of their pointy cusps grinding powerfully against the grooves of the upper molars, these injuries are the most common and may leave you with a broken cusp requiring extensive treatments. You must fix chipped tooth if you have a fractured cusp in the molars because the area becomes a breeding ground for bacteria and food particles to remain trapped and create additional damage to your tooth. In such cases, the dentist recommends treating the broken cusp with a tooth restoration like a dental crown.
However, if you have very fine lines or craze lines as they are also known, you might not require treatment. Instead, the dentist may polish the tooth to eliminate any rough spots to ensure the chip doesn’t cause any discomfort in your mouth.
A minor chipped front tooth is restored by dentists using tooth-colored filling material to replace lost enamel. You can also inquire with the dentist about getting dental bonding to fix the chipped tooth and restore it to appear like your natural teeth. However, do not try to fix the tooth yourself because you might create additional damage in your mouth.
Many people assume a chipped tooth is a minor problem that does not cause any significant issues. However, every chip or crack other than craze lines occurring on the enamel needs an evaluation from your dentist because trying to determine the intensity of the damage is pretty challenging for yourself. There are no effective home therapies to prevent additional injuries to your teeth, and the sharp edges of the chipped tooth can cut through your soft tissues to cause more pain and infection, needing expensive treatment. In some cases, an untreated chip can require a root canal, tooth loss, or other complications because of an infection.
You can use home repair kits available with drugstore and online retailers to cover the chipped tooth while you wait for an appointment to see your dentist. However, do not delay the treatment for too long because the bacteria in your mouth will undoubtedly get to the chip and, through it to create more infections in your mouth. | 4,280 | 1,913 | 9,528.761108 |
warc | 202143 | Colorado experienced its first winter storm system of the season on Tuesday and with more snow and poor driving conditions in the forecast, we'd like to refresh you on the state's traction and chain laws.
The state's traction law is in effect between Sept. 1 through May 31 on Interstate 70 from Dotsero to Morrison. However, in other areas the law could be activated during a winter storm, or in windy situation, according to the Colorado Department of Transportation.
The traction law focuses on passenger vehicles traveling through Colorado and requires drivers to have one of the following:
An AWD or 4WD vehicle with at least 3/16" tread depth Tires with a mud or snow designation (M+S Icon) and 3/16" tread depth Winter tires (mountain-snowflake icon) and 3/16" tread depth Tires with an all-weather rating by the manufacturer and 3/16" tread depth Chains or other approved alternatives such as an AutoSock.
Other laws in place include the chain laws, which are more geared towards commercialized vehicles during a severe winter storm. However, in some situations passenger chain laws will go into effect.
Code 16, or the passenger chain law, is the state's last step before closing a highway, according to the Colorado Department of Transportation.
When in effect, every vehicle on the roadway must have chains or alternative traction devices such as the AutoSock.
Drivers who violate these regulations could face fines ranging from $133 to over $1,200, said Trooper Josh Lewis, a spokesman for the Colorado State Patrol.
For instance, drivers of passenger vehicles who fail to comply to the tire restriction would face a $133 fine. If the same driver were to cause a road closure because of failure to comply, they would face a minimum fine of $657, Lewis said.
Fines on commercial vehicles are much harsher than passenger vehicles as failure to comply to the traction law would result in a $579 fine. Fines on the same vehicle for closing a road for failure to comply would cost over $1,200, Lewis said.
For additional information regarding traction and chain laws, click here. | 2,102 | 1,005 | 4,362.957214 |
warc | 202143 | Any car buyer knows how intimidating it could be to for you to car looking for service. Unless you have a real understanding of car parts and the direction they work, the parts your mechanic tells you need to get replaced might seem like a language of choice! We’ll more than some in the more strange names of car parts so when you find yourself in the know the subsequent time your mechanic claims that your caliper has to be swapped out!
Classic car is expected term to refer to an older automobile process. Those more than 25 year-old already could fall under this connected with car. One group named the Classic Car Club of America (CCCA) can be a leading authority for such collectibles. Classic vehicles these are those produced between 1925 and 1949, whether it local or foreign. Right here is the pre-war term.
Start that’s not a problem front finished. Replacing the wheels or forks can establish sweeping variations in the look of the bike, but smaller details like axle covers add subtlety that really separates you from the audience.
If may well be a problem by using a part of one’s car, some sort of mechanic are available you fresh part to buy a fairly good price. People go into car mechanics for many different reasons. Men and women visit for need new oil, new wheels, a flat tire, among other good reasons why.
Please take note that autos manufacturer doesn’t always manufacture the Car Parts you are replacing. For example, many cars have Bosch fuel injectors inside the middle of the vehicle by the manufacturer. In these cases, Bosch fuel injectors are the real replacement. Anyone have buy your fuel injectors from Ford, they may appear in Ford packaging even though they are Bosch injectors. If a person online and receive them in packaging such as Bosch, it does not mean effectively not trustworthy.
The second type of after market Motorcycle Parts that aftermarket parts dealers carry are custom motorcycle work pieces. Not every aftermarket dealer will have custom parts but it remains a choice to along with your lot. After all if they don’t maintain part likely are looking for they may know how to obtain that part for clients.
Safety quite. Never underestimate the significance about safety when you are conducting DIY motorcycle parts installation. One wrong move in doing your task can start a serious injury, or even cost you your situation. So, follow the necessary precautions. If the manual says you should use goggles or gloves, do the game. This may seem small matters, yet they can mean a lot to completing your tasks without problems.
Take a person to find appropriate parts for your needs as well as get method that you can pay for. Many dirt bike riders will want the best ones with the best prices they may well. If you research a two weeks you are usually able to obtain a better deal upon your motorcycle parts and can really clog be happier with an individual end develop in your immediate future. You in order to able delight in your bike without in order to worry about any eventuality where if possible have be concerned about a part you for you to replace. A great idea is the right bike in the first place and get to riding! | 3,211 | 1,626 | 6,273.891144 |
warc | 202143 | What is Inventory Financing?
If you have cash flow problems but need to purchase inventory, consider inventory financing. Use this type of loan to buy inventory, while also leveraging it as collateral.
Suitable for retailers and wholesalers, inventory financing provides cash amounts exceeding those of other nontraditional bank loans and invoice factoring.
Inventory financing is similar to asset-backed revolving lines of credit and term loans, but the asset used for collateral must be your purchased inventory. As the lender will need to assess your inventory operations, these loans require a thorough application process, possibly involving a third party. Given the effort required, lenders generally won’t waste time with loan requests less than $500,000-$700,000.
How Does Inventory Financing Work?
Lenders will typically advance 60-90%* of your purchased inventory’s liquidation value (as opposed to market value) through a line of credit or a term loan. With a line of credit, you can draw funds when needed, and make interest payments to restore the maximum limit. With a term loan, you’ll get a lump sum upfront and pay it back in monthly installments.
* Note that this means they can seize 100% of your collateralized inventory, while only advancing you 60-90%.
As with any “secured” loan, lenders have a right to seize assets upon default. In this case, they’d seize the inventory you bought with the loan. Many business owners may feel more comfortable taking a loan backed by inventory, as opposed to cars, property or invoices. After all, they figure, if the product can’t be sold, what do they lose anyway?
However, lenders also understand this logic and will practice extreme due diligence evaluating applicants’ inventory and business operations. While the loan itself is pretty straightforward, the application process leading up to an agreement (or rejection) requires patience and an understanding of risk assessment.
Why Use Inventory Financing?
Before seeking a loan, first, see if your supplier will allow you to buy on credit. This is obviously a simpler arrangement and likely to be cheaper. If this is not an option, definitely consider a third-party source of funding.
Before applying for inventory financing, you should first determine whether you’re a suitable candidate. Otherwise, you may get tangled in a lengthy application process only to be denied.
Inventory financing can be ideal for wholesalers, retailers,or any company that purchases inventory
andsells products. Service industries will notqualify.
As usual when shopping for loans, first determine whether you’re eligible for a traditional bank loan. If not, and you’re seeking to purchase inventory worth at least $500,000, inventory financing could be the solution to your cash flow problems. For instance, if you’re car dealership looking to fill up your lot before the busy season, inventory financing could be perfect—especially if you expect quick proceeds to cover the loan.
Another question to consider is how much lender involvement you can tolerate. From the start of the application up until the loan is repaid, you can expect ongoing paperwork, inspections and appraisals, possibly even unannounced visits. With regular business lines of credit and short-term loans, however, after the initial check of your credit score and a few other financial documents, you’ll be left alone, as long as you repay.
Whether or not you should use inventory financing may come down to preferences. If the loan amount you need requires collateral, you may be happy to put up the purchased inventory if you deem your other assets ‘untouchable’. But some business owners just don’t have the time to get approval or the sales prospects to pay off such an expensive loan.
Pros of Using Inventory Financing
Obtain a significant loan amount (more than $500,000)
Use purchased inventory as collateral rather than cars, houses, invoices, etc.
Get the built-in incentive to sell your products!
Cons of Using Inventory Financing
Pay higher interest rates than you would on traditional loans
Expect frequent inspections and appraisals (sometimes unannounced)
Get a loan of only 60-90% of your collateralized inventory’s value
Inventory Financing Rates, Cost & Terms
Inventory Financing rates range from 8-35%. Generally, the less the lender will advance, the lower the interest rate. The lower the interest rate, the more due diligence. Banks will only fund up to 60% of the inventory value, but offer rates in the single digits. They will also spend at least a few weeks–possibly a few months on appraising your inventory. Other lenders, however, may be willing to fund up to 90%, but rates will be substantially higher. While they’ll also practice due diligence, their approval process will likely last from 1-3 weeks.
8-35%
Interest Rates
$500k+
Loan Amount
650+
Credit Score
15 days+
Funding Speed
Part of what makes inventory financing expensive is its duration of only one year, which is a relatively short time to pay back the loan with interest. In addition, you can expect fees for inspection and appraisal.
Some non-traditional lenders advertise “inventory financing”, but you’ll be puzzled to find no collateral required. After all, isn’t the point of inventory financing to leverage purchased inventory as collateral? Don’t be fooled by the gimmick. This just a regular line of credit or short-term loan dressed up as “inventory financing” for marketing purposes. They’re merely targeting business owners who want to boost their inventory. The loan is advertised to free up cash flow to purchase inventory, but in reality, borrowers can use it on anything, as long as it’s repaid.
How to Apply (and hopefully qualify)? To be considered for approval, your desired loan amount should be at least $500,000. Again, lenders won’t invest the time appraising your inventory for anything less. Your lender also needs to know that your inventory is liquid and marketable. Despite what you pay for your inventory, the lender needs to know that it can be turned into cash, should you default on the loan. This is what prolongs the application process, as the lender and/or third parties evaluate your products, inventory management system, loss or damage rate, profit margins, and turnover. Keep in mind that even after initial approval, lenders may wish to repeat inspections every 3-6 months. You’ll also need to provide financial statements, tax returns, proof of business ownership, credit score and other relevant documents showing the health of your company. Inventory financing is not ideal for start-ups or new businesses with less than a year (or more) of consistent revenue.
As inventory financing is usually a second or third option, lenders will often ask if you’ve first considered other forms of alternative financing. Therefore, it may help to read our guides on regular business lines of credit, short-term business loans and invoice factoring.
If inventory financing is the type loan your business needs, our manging director would love to help you with the application process. Contact us now. | 7,291 | 3,183 | 16,240.398995 |
warc | 202143 | Terminologies of Music What are the Terminologies of Music? What are the Terminologies of Music? Etymology: Etymology:
The term music originates from the Greek mousike, which means “art of the Muses”. The Nine Muses were goddesses in Greek mythology who inspired literature, science, and the arts, and were the source of knowledge represented in Greek poetry, song lyrics, and stories.
The word “music” is come from “mid-13c., musike, from Old French musique (12c.) and directly from Latin musica, “the art of music,” also including poetry, (also the source of Spanish msica, Italian musica, Old High German mosica, German Musik, Dutch muziek, Danish musik), according to the Online Etymological Dictionary. This is a result of the Greek mousike (techne) “Muse (art),” from fem. of mousikos “pertaining to the Muses,” from Mousa “Muse” (see muse (n.)). The modern spelling of the word comes from the 1630s. [The term “music”] refers to any art in which the Muses reigned in ancient Greece, but notably music and lyric poetry.
Art and Entertainment: Art and Entertainment:
Music is created and performed for a variety of reasons, including aesthetic enjoyment, religious or ceremonial purposes, and as a commercial entertainment commodity. Music enthusiasts would acquire sheet music of their favorite pieces and songs when music was only accessible in sheet music scores, such as during the Classical and Romantic eras, so that they could perform them at home on the piano.
When the phonograph was invented, recordings of popular songs, rather than sheet music, became the most common means for music fans to enjoy their favorite tunes. Music fans may build cassettes or playlists of their favorite songs and take them with them on a portable cassette player or MP3 player after the introduction of home tape recorders in the 1980s and electrical music in the 1990s.
Amateur musicians might write or play music for their personal enjoyment while earning money from other sources. Armed forces (in marching bands, concert bands, and popular music groups), churches and synagogues, symphony orchestras, radio or film production businesses, and music schools are among the institutions and organizations that employ professional musicians.
Professional musicians may work as freelancers or session musicians, looking for contracts and engagements in a range of situations. Between amateur and professional musicians, there are frequently numerous connections. Amateur musicians who are just starting out receive instruction from expert musicians.
Music played in front of a live audience is typically distinguished from music performed in a studio for the purpose of being recorded and transmitted through the music retail or broadcasting systems.
However, a live performance in front of an audience is frequently filmed and distributed. Live concert recordings are prominent in classical music as well as popular music genres like rock, where music fans reward illegally captured live events. Studio recordings are favored in the jam band scene over live, improvisational jam sessions.
composition: composition:
The act or practice of writing a song, an instrumental piece, a work that includes both singing and instruments, or another form of music is known as “composition.” Composing comprises the development of music notation, such as a sheet music “score,” which is subsequently performed by the composer or other vocalists or musicians in various cultures, including Western classical music.
The act of creating, which is commonly referred to as song writing in popular and traditional music, may entail the development of a basic sketch of the song, known as the lead sheet, which includes the melody, lyrics, and chord progression. The composer orchestrates his or her own works in classical music, while songwriters in musical theatre and pop music may employ an arranger to orchestrate their songs.
A songwriter may choose not to use notation at all, instead composing the song in her head and then playing or recording it from memory. Famous recordings by influential artists are given the same weight in jazz and popular music as written scores are in classical music.
Even when music is notated quite accurately, such as in classical music, a performer must make several judgments since notation does not completely define all of the aspects of music. The term “interpretation” refers to the act of determining how to perform music that has already been written down and notated.
The tempos used, as well as the playing or singing style or phrasing of the melodies, might differ greatly across different artists’ renditions of the same piece of music. Composers and songwriters who play their own music, much like those who perform other people’s music, are interpreting their own tunes.
Notation: Notation:
In the 2000s, music notation referred to the use of symbols to write down music notes and rhythms on paper. The pitches and rhythms of music, such as melody notes, are notated when they are written down. Instructions on how to execute the music are typically included in the music notation. For example, a song’s sheet music may specify that it’s a “slow blues” or a “rapid swing,” indicating the speed and genre. To read music notation, one needs to be familiar with music theory, harmony, and the performing conventions associated with a song’s genre.
Improvisation: Improvisation:
Musical improvisation is the process of creating music on the spot, usually within (or based on) a pre-existing harmonic framework or chord sequence. Improvisers employ chord notes, multiple scales connected with each chord, chromatic ornaments, and passing tones that aren’t always chord tones or scales linked with a chord. It is possible to perform musical improvisation with or without prior preparation. Instrumental artists improvise solos, melody lines, and accompaniment sections in some kinds of music, such as blues, jazz, and jazz fusion. | 6,129 | 2,714 | 13,443.602432 |
warc | 202143 | The Department of Science and Technology (DOST), despite dropping one rank at 51st in the Global Innovation Index (GII) for 2021 from last year’s 50th, maintains its strong bearing that “it remains committed in bringing science closer to society, empowering Filipino-made breakthroughs and innovations to increase productivity and drive prosperity.”
World Intellectual Property Organization Assistant Director General Marco Aleman, emphasized that the country’s 51st ranking puts the Philippines “together with China, Turkey, Vietnam, and India as part of the group of the only five countries, which made significant progress in the GII innovation rankings overtime.”
Aleman added that the country continues to lead among the developing countries in setting innovation as a national priority.
In the GII 2021 report, the Philippines ranked 4th among the 34 lower middle-income group economies and 11th among the 17 economies in Southeast Asia, East Asia, and Oceania. With roughly 80 indicators, the Philippines considerably performed well as the GII ranks the countries in the world with their innovation capabilities.
In the last three years, the innovation inputs or the investments for these activities in the Philippines remain low, ranking at 72 compared to 70 in 2020 and 76 in 2019. However, despite the low input, the ranking for innovation outputs or the resulting programs and technologies from such investments, is rising, with the Philippines at rank 40 in 2021, a step higher from the 41st ranking in 2020. This reflects the efficient implementation of R&D programs that resulted in high outputs despite limited funding.
For his part, DOST Secretary Fortunato T. de la Peña underscored that the Science Department’s R&D priorities have shifted due to the COVID-19 pandemic and has refocused its efforts on the development of diagnostic or test kits, biomedical devices, disease modelling and surveillance applications, among others.
He added that “the world seemed to be in a halt,” describing the early months of the pandemic during the virtual presser held on 21 September 2021 in time for the launch of this year’s global innovation report. “But despite the negative impacts in the implementation of [its] Science, Technology, and Innovation activities,” said de la Peña,
“the Department became flexible enough and has adopted timely strategies, enabling the country to respond to the situation at hand.”
Despite the challenging times, de la Peña also mentioned that several initiatives were done to ensure food security with programs and projects geared at improving crop, livestock and fisheries production. In addition, the Department strengthened its collaboration with stakeholders that allowed value adding activities to ensure food resiliency in the new normal. DOST also fast tracked its health research and development efforts and brought in the intensified Tuklas Lunas Program to support the country’s drug discovery and development efforts.
Moreover, the science chief disclosed that in the last four years, DOST’s scholarship programs produced over 500 MS and PhD graduates in the Science, Technology, Engineering, and Mathematics fields at different level per year and “awarded more than 10,000 MS/PhD scholarships across the country from which more than 4,000 scholars already graduated.”
To sustain its pool of S&T experts, the DOST continuously engages 577 Balik Scientists across the 16 regions of the country, further strengthening the R&D efforts through the Science For Change and Balik Scientist programs.
And to ensure equitable R&D funding across the country, the DOST is strongly pushing for the passage of the Science For Change Bill to lawmakers which will “allow the establishment of more R&D and Innovation centers in the regions,” revealed de la Peña.
This was affirmed by DOST Undersecretary for R&D Rowena Cristina L. Guevara who said that “the DOST is lobbying for the passage of the Science for Change (S4CP) Bill. Approval of the said bill would mean the continuation of the inclusive, equitable and sustained efforts for innovation, given the optimal use of our resources for R&D.”
On a positive note, the House of Representatives recently approved in third and final reading the creation of the Virology and Vaccine Institute of the Philippines to serve as the country’s premiere R&D institute in the field of virology and vaccine development. This health system infrastructure will contribute to the country’s efforts in addressing possible future health issues.
In another front, Department of Trade and Industry (DTI) Secretary Ramon Lopez shared that this year the country continues to perform better in terms of innovation output compared to the innovation inputs.
He explained that the country is “able to produce more and higher quality innovation output despite our limited innovation resources and pandemic induced setbacks.”
This development reflected GII’s observations that the Philippines continues to be among the countries that perform above expectations given its current level of development.
Lopez further emphasized that the Philippines rank first in the world in both high technology exports and imports as percent of trade while maintaining the 10th place in the creative goods export as percent of trade. He also pointed out that the domestic market scale, trade openness, firms offering formal training, and ICT services exports continue to be the country’s strengths.
“The 2021 GII highlights that many industrial competitiveness indicators remain to be our strengths,” Lopez continued. Incidentally, the DOST has established strategic partnership with the DTI to jointly pursue harmonized initiatives to achieve economic development by using science, technology, and innovation.
The GII is an insightful data published by the World Intellectual Property Organization to help countries evaluate the innovation performance each year and help stakeholders map out plans for economic improvements and developments. It ranks the innovation ecosystem performance based on 80 key development indicators as its metrics. (By Joy M. Lazcano, DOST-STII) | 6,312 | 2,851 | 13,551.649246 |
warc | 202143 | tools
Despite the fact that there have been numerous advancements in the way of treating mental disorders in the past 50 years, there may be nonetheless a sure stigma surrounding the views on psychological illness. Any person taking good care of an addict wants to know these tips. Really addicts experience more deficiencies together with Vitamin D, K, C, B2 and others. Deficiencies of a few of these vitamins may result to poor functioning of the mind and even cause severe damage. Probiotics and prebiotics included in Everyday Vitamins and Minerals help maintain a healthy intestine microflora, which is significant for keeping the immune system working, to produce vitality to provide body warmth to maintain horses and ponies heat, and to digest fibre to produce vitality used to take care of bodyweight and to work.
If you’re an skilled CBD client, you could be snug experimenting with excessive-power CBD oils. Simply …Read More
Group fitness lessons are the perfect solution to keep match and wholesome. Sadly, the vast majority of folks that I know shouldn’t have a focused plan to of their fitness quest. Take into consideration your health in an identical approach as you consider a job and you’ll reap much better outcomes out of your program. The phthalides in these vegetables additionally stimulate the secretion of bile juices, which work to reduce levels of cholesterol. Much less ldl cholesterol means much less plaque on the artery partitions and a general improvement in heart well being. The fiber that is found in it additionally works to scrape the cholesterol out of the bloodstream and eliminate it from the body with regular bowel actions, further boosting cardiovascular well being.
In response to Dhar, there’s a wide range of “regular” bowel actions. Regardless of what various blogs or well-known TV medical doctors say, you …Read More
In case your time is limited, as an alternative of making an attempt to slot in three or 4, 30 minute workouts a week, strive shorter, but more frequent walks. Vitamin C can also be beneficial to a nutritious diet and located in watermelon. The coronavirus pandemic has been onerous for everyone, however particularly so for individuals with severe mental health issues, she explains. Additionally, individuals who follow vegan diets, especially if pregnant, might profit from vitamin B12 supplements. A thimble may simply contain the distillation of all of the trace minerals normally found in your body. Yet their contributions are simply as essential as those of main minerals equivalent to calcium and phosphorus, which every account for more than a pound of your body weight.
Milk accommodates small quantities of copper, iron, manganese, and sodium and is not thought-about a major source of these minerals in the food plan. …Read More
Physical health is the flexibility to operate successfully all through your workday, perform your regular different activities and still have sufficient vitality left over to deal with any further stresses or emergencies which can come up. When you’ve ever slept on a nasty mattress you possibly can totally understand the importance of comfort to a very good night’s sleep. If a affected person is unable to maneuver themselves, the body turns into extremely stiff and uncomfortable, resulting in disrupted sleep. With the fixed mild turning offered by an air pressure mattress, the patient is ready to have a solid nights relaxation which finally helps improve overall bodily and emotional well being. Always, all the time, warm up first. Take your body via fundamental movements that can loosen and stretch your muscular tissues. This can be certain that your body performs at an optimum stage and extra important, you keep away …Read More
The name DP train bike won’t be as recognizable as other brands like Schwinn, Nautilus and ProForm, however this brand has been around for fairly some time and is without doubt one of the most respected names within the physical fitness business. It takes one small step to search out the tools and assets you might want to improve your wellbeing and stay healthy, lively and related. With improvements in testing, however, medical doctors are now capable of determine some bodily indicators of some varieties of psychological sickness in CT scans and genetic assessments. Fitness Training for Pre- and Post-Natal Pregnancy: This type of program is designed to strengthen the lower again as well as present stress-lowering train methods. In response to the Facilities for Illness Control and Prevention (CDC), healthcare prices in the United States had been $3.5 trillion in 2017.
A good weight loss program will often be …Read More
Are you looking for a special means to improve your eye well being and your basic health at the similar time? If you’re interested by beginning a vitamin and mineral supplement, first consult your physician. For those who take any medications you’ll want to test and ensure that a complement is not going to intrude with your remedy. You may additionally wish to seek the advice of a doctor if you wish to discover out if there’s a particular vitamin or mineral that your are lacking in your system. For normal general health although, many individuals discover that a multivitamin supplement is the perfect type of vitamins to take.
A low SES often means decreased entry to healthcare. A 2018 research in Frontiers in Pharmacology indicated that folks in developed international locations with common healthcare services have longer life expectancies than those in developed international locations without common healthcare. In …Read More | 5,729 | 2,786 | 11,569.043073 |
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By Chemistry World2017-08-23T07:00:00+01:00
Cycling strategy leads to massive efficiency boost
Source: Royal Society of Chemistry
Lithium could hold key to sustainable ammonia synthesis was first published by Chemistry World.
2021-10-13T06:30:00Z
Link forensic science and the Covid-19 pandemic to your lessons on instrumental analysis, separation techniques, data interpretation and health with UN sustainable development goals 16 and 17
Ryley develops cutting-edge solar cell technology to make solar power cheaper and more efficient so that this renewable source of energy can become more mainstream.
Lizzie investigates new battery materials for lithium-ion batteries which power devices such as smart phones, laptops and electric vehicles.
2021-10-15T09:13:00Z
Scientists dispel the theory that sunlight exposure simply fragments macroplastics that persist in the environment, but what are the implications for the environment?
2021-10-01T06:25:00Z
The amorphous carbon material created from buckminsterfullerene
2021-09-08T06:53:00Z
Delve into the dissolving device making recycling easier
Site powered by Webvision Cloud | 1,428 | 832 | 2,421.764423 |
warc | 202143 | Greg Otto conducts risk assessments for a living, but the cybersecurity consultant from Springfield, Va., never imagined he’d have to do one every time his daughter, 6, and son, 4, stepped outside the boundaries of their home. Playing with next-door neighbors outdoors? Acceptable. School? Necessary. Eating out? No way.
Dance classes where everyone’s masked, and that were prepaid in June when the outlook for coronavirus infections seemed more optimistic? On the fence. “This is insanity,” said Otto, 37. Parenting a child under 12 can be maddening and scary during normal times, but the delta variant has taken things to a new level. With a vaccine for children ages 5 to 11 unlikely to be approved for at least a few more months, parents of young children are weighing a dizzying array of variables every day as they try to navigate the risks of covid against the mental health and physical consequences of social isolation and their own livelihood.
Breanna Contreras, 33, an intellectual property attorney whose children are 6, 3 and 20 months, said she and her husband, an engineer at Los Alamos National Lab, made the difficult decision to put all three of their children in school or day care because of their demanding jobs. But she second-guesses the choice every day.
“I feel like we’re constantly reacting,” said Contreras, who lives in Santa Fe, N.M. “There’s not enough time to be proactive. It’s like a fire alarm every day.” In Crofton, Md., Lise Dykes, a graphic designer and mother of two, ages 7 and 11, has been thinking a lot about a cartoon she saw recently that features a parent staring at a vast ocean. She recalled that it said something like: “Only 1 percent of the children are going to get eaten by the shark. It’s fine.” Dykes, 48, said the continued reassurances by health officials and experts that children are at low risk from serious illness are difficult to relate to when you are faced with your own children. Even school, which seemed like a hopeful and sensibly calculated risk in May, she said, now feels “like an incredibly dangerous roll of the dice.”
At a time when more than 75 percent of U.S. adults have received at least one vaccine dose and just about everything has opened up, the American Academy of Pediatrics reported over 250,000 new coronavirus infections in children just last week — the highest ever during a pandemic that is stretching into its 18th month. Nearly 30,000 adolescents and children were hospitalized with covid in August, and many are unvaccinated teens and tweens, or newborns to 11-year-olds who are not yet eligible for shots. Four-hundred sixty have died, representing 0.01 percent of all child cases.
The risks of long covid in children — which could include respiratory or cardiac problems, fatigue, brain fog and other symptoms that can last for months or, potentially, years — remain a big unknown. An Israeli study, one of the first on the topic, of 13,864 children published this week, found that 11 percent of those infected had signs of long covid. Israel’s Health Ministry emphasized, however, that some of the children’s symptoms may also be due to prolonged lockdowns, school closures and global conflict including the fighting in the Gaza Strip.
The timeline for vaccines for the youngest Americans came into more focus this week. Pfizer CEO Albert Bourla said Tuesday that the company plans to submit data in late September seeking approval to administer its vaccine to children ages 5 to 11 and that it expects to release clinical trial data as soon as late October for ages 6 months to 2 years. The Food and Drug Administration must review the data and make a decision. The agency in July had asked Pfizer and Moderna, which make the two vaccines that use mRNA technology, to expand their trials in children following concerns about a rare heart complication in some adolescents and young people.
‘It felt impossible for me’
Bernadette Castro, 43, is a mom of three boys too young to be vaccinated: Axel, 8; Jude, 6; and Bash, 4.
After she was furloughed and then laid off from her job as a production manager for the Blue Man Group in spring 2020, she suddenly found herself at their two-bedroom home in the Queens section of New York jumping back and forth between her two older sons’ Zoom classes while trying to “shhh” her youngest so he didn’t interrupt the other two.
As things opened up during the summer, she was rehired by her old employer, and the family ventured out more. While she considers the family’s previous indoor hangouts of the New York Hall of Science and theater off-limits for now, she said the kids have found joy in going to the park every day and climbing everything. The trickiest part, she said, is that while surfaces do not appear to be a big factor in covid transmission, it’s more of a problem for younger kids like hers, who would “would lick the walls if you let them.”
She and her husband bought cargo bike seats and have been biking the kids to their school, which finally opened this month.
“This year was really rough,” she said. “I did like virtual therapy this year, and I’ve never done that before. A lot of parents struggle with finding time for themselves, but add covid on top of that, and it felt impossible for me.”
‘Everyone is pretending it’s all over, but it’s not’
A mother of four from Florida, Mary Lucia Spake has had to make some unpopular decisions for her family in recent days. The situation in her state, in which Gov. Ron DeSantis (R) has been fighting school mask mandates, has been among the worst in the nation this summer. As of Wednesday, it ranked third behind Texas and Ohio in terms of cumulative pediatric hospitalizations due to covid since July 1, according to a Washington Post analysis. The number of children hospitalized per day has jumped from about 20 a day in June to more than 100 a day in late August. The figure has fallen to about 65 in the past week.
“Having to tell my kids no to things that are good for them so many times makes me the most sad,” said Spake,
While Spake, her husband and their three older children, ages 19, 16 and 16, are vaccinated, her 11-year-old, Vivian, is not, which means the risks everyone else takes could affect her. Moreover, Spake was diagnosed with breast cancer, making her potentially more vulnerable to complications if she were to catch a breakthrough infection.
Pre-covid, Vivian had played travel volleyball and loved it. This year, Spake and her husband had “lots and lots” of talks about whether to allow her to rejoin her team.
On the one hand, Spake recalled, they talked about how “she’s been inside so long and alienated from her friends” and how “these kids have sacrificed a lot and lost a lot” already. But they also talked about how four of the 12 children in Vivian’s sixth-grade class had to quarantine because of possible exposure to covid soon after the school year began. Being in the medical field — she’s a home health nurse, and he’s an attorney for a hospital — Spake and her husband also picked apart the latest research and local transmission
After many hours, they came to the conclusion that volleyball was off the table for now.
“This year is harder in some ways than last year,” Spake said. “Because everyone is pretending it’s all over, but it’s not.”
‘I’m waiting for the shoe to drop’
Maia Blankenship’s 4-year-old daughter, Zuri, has spent nearly half her life isolated at home during stay-at-home orders and a prolonged school closure in D.C. So Blankenship was thrilled to send Zuri off to her top-choice charter school this fall.
But her happiness has been tempered by a flurry of communications about positive cases across the city, resulting in numerous children being in a rolling quarantine.
“I’m waiting for the shoe to drop,” Blankenship, 45, said. “I feel fortunate I have a job, a home, a computer and a supportive employer, but it does not change the stress I have knowing my daughter did not have a real year of school last year and how important it is for her social-emotional well-being.”
Greg Otto said he feels as if life has been on hold forever, despite being vaccinated in April.
“We have no real plans, and the things we do are really at a bare minimum,” he said. “We have a bubble with kids on the block. I don’t do anything. My wife doesn’t do anything. We kind of stick to home.”
As for that dance class, he said, “to be very honest, my wife and I — I wouldn’t say we’ve had arguments — but we’ve had some tough conversations about it. The risk factor is higher than it was when we signed up.”
Otto did allow his children — a daughter in first grade and a son in preschool — to attend in-person school this fall, but that’s because he said he has no other choice: His district closed applications for a virtual option on May 28 before delta took hold in the United States, and the family cannot afford private school.
Otto said he’s frustrated by the fact that many school districts have not moved quickly to change their in-person plans in response to the surge, calling it “a stark failure, no matter how you politically view the pandemic.”
“We’ve been pushed into a situation that is terrifying,” he said, “and I feel like it’s unfair, and I don’t feel it has to be unfair.” | 9,749 | 4,605 | 19,565.745494 |
warc | 202143 | Auditing has become a compulsory task in business organization, so to detect and prevent frauds, auditing is very important.
Auditing services are very crucial for any smooth-running businesses for small, big and medium-sized enterprises. It ensures the integrity and transparency of the company’s Finance. Here is where the role of the auditors come into play, it is the responsibility of the auditors to present attested audit report which shows the company has presented an authentic and without discrepancies in financial statements.
Auditing is the inspection of various books of accounts by an auditor which is followed by physical checking of inventory. To make sure that all departments are following documented system of recording transactions.
The following are the helpful points provided by auditing in Dubai:
A financial statement audit ensures that the financial statements are in line with the reporting standards and is transparent as required by UAE law. Auditors make sure the cash flow of companies is smooth and due payments are cleared in a timely manner, they follow up with clients about payments. Auditing firms in Dubaihelps to keep the company’s financial statements consistent and updated, they improve the credit rating of a business. Auditing firms in Dubaioffer genuine and accurate financial stability for businesses and they equally avoid miscalculation of financial statements. Auditing services in Dubaihelps businesses to determine their profit or loss (balance sheet) at this point the owner of the business can get information about profit or loss after auditing the books of accounts. Many businesses have been able to gain clarity of their financial positions with the help of auditors in Dubai. Auditing helps to identify the issues occurring in the internal management and also give remedial solutions to assist the company in taking the necessary steps to eradicate the root of the problem
The three main areas where auditors look at are;
Balance Sheet Income Statement Cashflow Statements
As per UAE law, every company must audit their financial statement every year. Therefore, it is imperative and beneficial for every company to audit their financials and at this point
auditing services in Dubai (UAE) is very helpful for every organization. | 2,308 | 1,077 | 4,903.160631 |
warc | 202143 | Hair thickening in hair loss – how does it work?
Have you noticed that all of a sudden your hair has become increasingly thinner and you’ve started to become envious of people with thick bountiful hair?
We understand why you are feeling this way, and we can assure you that they are using various hair thickening techniques to maintain their generous head of hair. Let us share a few of their secrets with you.
Summary
What is hair thickening? What are the natural remedies for hair thickening? What causes hair thinning? Can hair thickening be achieved through a hair transplant? Does frequent hair washing prevent hair thickening? Conclusion: a permanent hair thickening solution What is hair thickening?
Hair thickening is a broad term that refers to either:
the permanent process of hair transplants the temporary hair treatments that make hair appear thicker.
These treatments work to maintain and improve the quality of the existing hair and reduce breakage and hair loss. On the other hand, a hair transplant is a procedure that only needs to take place once to result in a thicker head of hair.
Although there are natural hair care techniques that help to slow down the process of hair breakage and hair loss, alopecia in both men and women is usually genetic and will occur at some stage throughout a person’s life.
Usually, individuals turn to natural hair care methods to improve their hair strength and slow down hair breakage with the aim to delay baldness and receding hairlines.
What are the natural remedies for hair thickening?
Egg Hair Treatments:Egg hair masks are high in protein which helps to strengthen hair follicles to result in thicker hair. Olive Oil Hair Treatments:The Omega3 properties in olive oil help to promote thicker and healthier hair when applied directly to the scalp. A Nutrient Rich Diet:For thicker hair, food that’s rich in protein, fatty acids and Omega-3 are beneficial. Avocado Hair Treatment:Rich in vitamin E, Avocado is an impressive moisturiser which can be made into a hair mask mixed with olive oil to promote the growth of healthy hair. Castor Oil:castor oil is an effective hair treatment for hair thickening when rubbed into the scalp as part of a hair mask treatment.
Natural hair thickening methods will help to keep your hair healthy and luscious but this isn’t a solution that has a lasting effect. A hair surgery through the FUE method will be the only way to permanently recover your hair.
What causes hair thinning?
Both men and women may experience hair thinning in their lifetime which can be caused by various factors. Thinning hair can be caused by many things:
poor nutrition illness overuse of hair products containing harsh chemicals genetics
Women can also experience hair thinning from pregnancy and polycystic ovary syndrome (PCOS).
Can hair thickening be achieved through a hair transplant?
For the first few months after a hair transplant, the hair follicles will be quite delicate. Especially while they begin to settle in their new place. Once they’ve settled they will blend seamlessly with the untouched hair follicles.
Within a year, the hair will begin to grow and fill the areas that were previously thinning to result in a fuller head of hair.
Using the FUE hair transplant method for hair thickening
A hair transplant is a permanent hair thickening solution that only needs to take place once in a lifetime. It’s a minimally invasive procedure whereby the surgeon removes the hair follicles that are healthy and robust.
These grafts are then inserted one-by-one into tiny incisions in the scalp, made by the surgeon, in areas where the hair is thinning. The FUE method is a preferred method of hair transplantation, compared to the FUT method.
It only causes minimal tissue scarring where the hair follicles were removed. Those will disappear when your natural hair grows back. The hair follicles that are grafted from your donor area are more resistant to DHT, the hormone that is responsible for hair loss.
Does frequent hair washing prevent hair thickening?
Washing your hair every day is a huge no because it will dry out your hair and scalp and prevent hair thickening. Shampoos are designed to strip the hair of built-up oils which comprises dead skin cells and product residue.
In the process of cleaning the hair of this build-up, “good oils” that are required for healthy hair growth. Those are also stripped as even the best shampoos can’t differentiate between the good and bad oils. This results in a dry scalp that can lead to excessive hair breakage and can cause hair to fall out.
Using mild shampoos and washing the hair 2-3 times per week can help to keep the scalp from becoming too dry. This will maintain healthy hair growth in the short-term. Unfortunately, it will not stop long-term hair loss which is unavoidable due to genetics and other factors.
Have you tried Dr. Balwi’s shampoo and hair spray?
Thanks to a unique combination of ingredients your hair receives the essential nutrients that nourish the roots and hair, and prevent their loss. Our shampoos and sprays are highly concentrated biotin, collagen and natural extracts (green tea, red ginseng). In addition unlike ordinary hair care products, ours tackle the problem at the root by cleansing the follicles and strengthening the shaft. Because a stronger and vitalised scalp produces more resistant and, of course, thicker hair!
Conclusion: a permanent hair thickening solution
Haircare shampoos can be used to help improve and maintain the strength of the hair and promote hair thickening. On the other hand a hair transplant is a permanent solution for hair loss that only requires one procedure to achieve thicker hair that lasts.
The hair surgery takes the root of the hair, which never loses their genetic data, to produce strong growing hair evenly across the scalp. Even when the hair is transplanted to another location on the scalp, the hair continues to grow vigorously. | 6,037 | 2,583 | 13,901.694154 |
warc | 202143 | Dentists from RUDN University Presented a New Classification of Root Canal Shape Changes
A root canal is a hollow space in a dental root with blood vessels and nerves going through it. Root canals have different shapes and width which makes treating them extremely complicated. Turns and shape changes can occur both in the coronal (visible) part of a tooth and in other parts that are invisible to the eye. Previous studies were focused on the curvatures of root canals in either the upper (coronal) or the lower (apical) part of a tooth. But a team of dentists from RUDN University carried out large scale research and presented the first-ever classification of root canal shape changes along its whole length.
“Earlier researchers tended to study about one-third of the root canal: either its coronal or its apical part. However, its shape changes along its full length, and this is an important factor for therapy. That is why we decided to take a look at the variations of root canal cross-sections in all three thirds and in different age groups of adult patients. Our goal was to develop a new classification of root canal shape changes,” said Svetlana Razumova, MD, a Head of the Department of Propaedeutics of Dental Diseases at RUDN University.
The team conducted an experiment that involved 300 patients from 20 to 70 years of age. The medics took CT scans of their healthy teeth in axial projection, i.e. the X-ray from the CT scanner moved along the roll axis of the teeth. This way the images showed the cross-sections of root canals. The team took 4,805 images in total and used them to study the changes in the shape of root canals depending on the part of a tooth. The images were processed using statistical methods.
The most widely spread changes in all age groups affected premolars (the teeth situated between canines and molars). In over 50% of cases, the shape of the root canal in premolars changed from round in the apical third into oval in the coronal third. Another place with frequent changes in root canal shapes was mandibular molars
Based on the obtained data the team developed a classification of root canal shape changes. The medics suggested dividing all possible changes into four groups: 1 — no changes in the shape, 2 — changes in the middle part of the root canal, 3 — changes in the middle and apical parts of the root canal, and 4 — changes in the apical part only. This classification will help dentists better understand the structure of each particular root canal and select proper tools to work with it.
“Our studies show that the shapes of root canal cross-sections can vary depending on the part of the canal and the age of a patient. All these variations were included in our classification and should be taken into consideration when choosing a method for canal cleaning. The choice of tools and preparation methods determines the efficiency of treatment at this stage and therefore affects the whole prognosis,” added Svetlana Razumova from RUDN University.
The results of the work were published in the Applied Sciences journal.
October 6, the Nobel Committee announced the 2021 Nobel Prize Winners in Chemistry. They were scientists Benjamin List (Germany) and David Macmillan (USA) for new methods of molecular synthesis. RUDN chemists know Professor Liszt personally — in 2019, the researcher came to participate in the university conference.
The Nobel Committee in Stockholm has named the laureates in Medicine — David Julius and Ardem Patapoutian. They discovered how temperature or touch, for example, is transformed into human sensations.
Allowing for quantum corrections, the Einstein-Lovelock theory describes black holes with an equation that contains an infinite number of terms. However, according to a RUDN University physicist, the geometry of a black hole in this theory can be presented in a compact form, and a limited number of terms can suffice to describe the observed values. This could help scientists study black holes in theories with quantum corrections to Einstein’s equations. | 4,122 | 1,899 | 8,801.848341 |
warc | 202143 | Gold Mining and the Mining Industry Association of Australia (MIAA) are reporting a gain of 2.33 per cent to $3.88 per share.
Mining companies are also benefiting from a 5.2 per cent drop in the price of gold and a 2.8 per cent increase in the amount of cash they hold.
Gemstone is down $1.10 to $2.47 a troy ounce and Gemstone Mining is down 6.8 percent to $1,828.00 per tonne.
Gold Mining stocks have rallied more than 4 per cent since the start of the year.
The MIAA has been on a sell-off in the wake of the mining tax, which will see the cost of mining be reduced to a flat 2.5 per cent for gold and 1.8 to 2.2 for other metals.
Gold prices have fallen by more than 1,500 per cent over the past 12 months.
The Australian Bureau of Statistics says mining taxes are one of the top two drivers of commodity price volatility in Australia.
It says the mining industry contributed to about one in five of the world’s commodity price fluctuations in 2017, and accounted for more than 70 per cent of global commodity price swings in 2016.
The ABC has been tracking the mining boom for the past few years, and has been closely following the industry’s fortunes.
The gold industry has been growing in popularity, with a $1 trillion market.
The mining boom has created jobs in Australia and overseas, but mining is also a major contributor to Australia’s debt.
Gold mining is an important part of the Australian economy and contributes to the nation’s economy, but the government has been keen to limit the impact of the tax.
The government is pushing ahead with a plan to slash the mining levy from 2.25 per cent in 2019 to 1.5 percent in 2021, and then 0.5 percentage points in 2022.
The tax has been a thorn in the side of gold miners since it was introduced in 2018.
It has seen some companies go into receivership and a few mining firms have gone into voluntary liquidation.
Topics:gold,mining-industry,mining,business-economics-and-finance,economics—other,business,economy,australiaMore stories from Australia | 2,051 | 997 | 4,132.857573 |
warc | 202143 | A majority of Brussels meal deliverers are said to work without papers and through fake accounts. This is according to a study by the newspaper Le Soir. The fake accounts are being used via social media for big money.
Just a few clicks to a Facebook group, that’s all it took to create a network until a network of Uber Eats accounts are generated. Who ‘borrows’ such fake accounts? Mainly young men who cannot have legal residence status. Through the fake accounts they can earn an income without having to provide a legal job. The accounts are ranked through groups on social media such as Facebook or in Whatsapp or Telegram groups. Those looking to purchase such a fake account via Deliveroo can deposit between 70 and 100 euros per week, for Uber Eats that amount will be between 500 and 700 euros.
bad working conditions
The big dupes in this story are the undocumented couriers who enter here. They cycle around without social security protection. In addition, they are sometimes forced to work 7/7 days to make ends meet. Courier companies such as Deliveroo have previously been criticized for paying their employees starvation wages. According to Le Soir’s agreement, it would earn 40 euros per delivery. On top of that comes a fee that the illegal couriers have to pay for a fake account. As a result, these couriers often drive around without rights in exchange for meager wages.
Zero tolerance and recognition technology
Uber Eats and Deliveroo themselves respond that they are doing everything they can to prevent abuse of their services. For example, they are working on various ways to better verify the identity of their couriers. According to Deliveroo and Uber Eats, they are working with restaurant operators and police to investigate suspected fraud. In addition, it contains a ‘zero tolerance’ principle against fraudsters. In the future, Deliveroo would like to develop a facial recognition system to verify the identity of their couriers. This is being tested in France and the United Kingdom.
(bzg) | 2,060 | 1,024 | 4,067.695313 |
warc | 202143 | LEARN MORE FREE TRIAL CONTACT EVIZONE In February 2014 alone, employees at the bank of Canada were flooded with 25,000 phishing emails encouraging them to open a document containing malware that would infect their computer and steal banking credentials. As the Financial Post reports, a good chunk of those emails were filtered out by the […]
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LEARN MORE FREE TRIAL CONTACT EVIZONE 61% of companies in the S&P/TSX Composite Index acknowledged cybersecurity as a material risk to their business. This was the main finding of the Canadian Securities Administrators’ (CSA) staff notice on the disclosure of cybersecurity risks and incidents. However, the CSA’s research is more much more troubling. While the […]
LEARN MORE FREE TRIAL CONTACT EVIZONE After the FBI and CIA both concluded that Russian hackers influenced the American presidential election, is it worth asking if this threat of interference exists in Canada? Yes, says former Canadian Security Intelligence Service (CSIS) director Richard Fadden, and it has probably already happened. The former spy agency head told […]
LEARN MORE FREE TRIAL CONTACT EVIZONE Unsurprisingly, the Democratic National Committee (DNC) is not the only organization vulnerable to Russian hackers. The infrastructures that allow you to live a comfortable modern life are at risk too. As Bloomberg reports: “Computer code connected to Russian cyberattacks by U.S. intelligence agencies has been found in a laptop […]
LEARN MORE FREE TRIAL CONTACT EVIZONE 2016 wasn’t a good year for Yahoo. After announcing in September that 500 million user email accounts had been hacked in 2014, it was revealed in October that the company itself had been spying on users and collecting the data for the NSA and FBI. Now, a new hack […]
LEARN MORE FREE TRIAL CONTACT EVIZONE This week, Canada’s fourteen privacy commissioners made a public declaration against increasing the government’s ability to decipher encrypted devices. According to the Globe and Mail, the group was led by federal Privacy Commissioner Daniel Therrien who stated that: “This is not the time to further expand state powers and […]
LEARN MORE FREE TRIAL CONTACT EVIZONE Last week, the Evizone blog introduced you to the growing safety concerns regarding unencrypted Internet of Things (IoT) devices. For the owners of the devices, a hack can mean a complete infiltration of a digital network, leaving all their data vulnerable. But the threat to corporations is just as […]
LEARN MORE FREE TRIAL CONTACT EVIZONE It’s one of those terms that gets thrown around whenever people talk about cybersecurity. Everyone has heard of it, but why is metadata so important, and why is it so vulnerable? Simply put, metadata is data about data. Let’s say you send a text message to someone. That text […]
(MONTREAL, QUEBEC, July 11, 2016) – Evizone Ltd., the Montreal-based software and services provider offering enterprise solutions in communications governance, secure messaging and regulatory compliance, today unveiled a newly revamped website and logo. The website offers a crisp, modern design with access to new tools and updated information about the company.
The changes follow recently improved new releases of Evizone’s Communications Governance content management system, which automates supervisory review, compliance, and e-discovery, and of its Secure Communications service, both protected by Evizone’s patented security.
“Our new look emphasizes Evizone’s philosophy of continuous improvement on all fronts,” said Bill Wells, Chairman of Evizone. “We are extremely proud of our products, developed by some of the best software engineers in the world. We provide the highest level of communications security commercially available in fast, easy to use systems. Our new look and new website reflect this level of excellence.”
LEARN MORE FREE TRIAL CONTACT EVIZONE To say that Hillary Clinton’s email problems were her downfall would be gratuitous, but there’s no question that it contributed to a certain narrative about her character and abilities. We’ll leave it to more suited analysts to conduct the postmortem on her campaign. However, now that Donald Trump is […] | 4,479 | 2,210 | 8,751.276923 |
warc | 202143 | Intermittent Fasting Helpful in Chronic Disease Management: Study
A recent study by an international team of researchers found that intermittent fasting can help prevent and manage chronic disease. The results of the study were published in the journal ‘Endocrine Reviews’.
According to the study, eating calories per day in a consistent 8-10 hour window is a powerful strategy for preventing and managing chronic diseases such as diabetes and heart disease. Time-limited eating is a type of intermittent fasting that limits your food intake to a certain number of hours per day.
Intermittent fasting is one of the most popular food trends, and people use it to lose weight, improve their health, and simplify their lifestyle. “People who are trying to lose weight and lead healthier lives should be more careful about when and what they eat. Time-limited eating is an easy-to-follow diet strategy. efficient that requires less mental math than counting calories, ”said Satchidananda Panda, PhD, of the Salk Institute for Biological Studies in La Jolla, Calif.
“Intermittent fasting can improve a person’s sleep and quality of life, as well as reduce the risk of obesity, diabetes and heart disease,” Panda added. In the study, researchers explored the science behind time-limited eating, recent clinical studies, and the scope of future research to better understand its health benefits.
Recent research has revealed that genes, hormones, and metabolism go up and down at different times of the 24-hour day. Aligning our daily habits with when we eat with the body’s internal clock can optimize health and reduce the risk or burden of chronic diseases like diabetes, heart disease, and liver disease.
“Eating at random times breaks the timing of our internal program and makes us prone to disease,” Panda said. “Intermittent fasting is a lifestyle that anyone can adopt. It can help eliminate health disparities and enables everyone to live healthy and fulfilling lives, ”concluded Panda. (ANI)
(This story was not edited by Devdiscourse staff and is auto-generated from a syndicated feed.) | 2,160 | 1,080 | 4,182 |
warc | 202143 | As a pup, Liberty was put through advanced enrichment training. He and his siblings began their training as neonates, at 3 days old. Over a period of ten weeks, Liberty and his siblings were put through a detailed course that started with Early Neurological Stimulation. They were exposed to Startle Recovery Training. To Ambient Noise Training. To Unusual Surface Training. Before Liberty knew what fear was, he was taught not to fear. During the time in his development when his neurological pathways were rapidly developing, he was exposed to a sundry of novel stimuli. He was taught how to calmly ask his handler for what he wanted and needed. Part of his training, called “manding”, involved techniques used to train human autistic children. In short, he was not taught WHAT to think, but rather HOW to think.
The result is a happy, healthy dog who is not afraid to cross a stream on a fallen log, or jump from a waterfall. He learns quickly, and remembers his lessons. He leads the other dogs in his social circle by example, simply by being who he is. Liberty’s siblings were distributed across the United States, from Michigan to Alabama, and from Pennsylvania to Arizona. They work as search and rescue dogs, as farm dogs, and as active lifestyle companions. Their owners provide a closed feedback loop which to date has been overwhelmingly positive. Liberty’s breed is a little-known, rare American dog breed called the English Shepherd. From within the breed, Liberty’s parents were chosen from bloodlines with elite athletic ability and an intense eagerness to please their handlers. | 1,623 | 886 | 2,921.766366 |
warc | 202143 | There are numerous ways AI can be applied in plastic surgery. From big data and machine learning to deep learning, natural language processing and facial recognition, AI-based technology provide plastic surgeons many means to advance their surgical practice. With this in mind, Dr. Sina Bari is optimistic that AI can modernize reconstructive and plastic surgery despite the early challenges facing the use of AI in healthcare.
Dr. Sina Bari’s Background in Tech
Long before Sina Bari became a medical professional, he had a strong passion for computer science. This is typified by his eagerness to learn to program at the young age of eight. While in high school, Sina Bari worked in parallel computing and networking via a National Science Foundation award before proceeding to undergraduate and medical school, which he paid for by working in IT.
In 2006, Sina Bari was one of three top medical graduates to be selected as participants in Stanford Hospital and Clinics’ 6 years accelerated Plastic Surgery residency. Here, he worked with leaders in the field to learn advanced techniques in craniofacial surgery, hand surgery, and reconstructive surgery.
However, Dr. Bari would later reconnect with technology as a plastic surgery resident, thanks to the bio innovation program at Stanford. Still, there was more to come.
Sina Bari eventually returned to the tech world years later as a solutions architect at iMerit, before marrying the processes he learned to his medical background in a bid to propel advanced healthcare practices. An example of this is his exploration of the use of artificial intelligence solutions in reconstructive and plastic surgery.
Dr. Sina Bari Reflects on AI in Reconstructive and Plastic Surgery
With a background rooted in tech, Dr. Sina Bari sees several potential applications of AI in plastic surgery. One such application is in AI analysis of wrist x-rays, as this could be used to improve the accuracy of detecting closed fractures of the hands and digits. These injuries take up a sizeable portion of a plastic surgeon’s workload, and if improperly diagnosed, they can have profound implications for affected patients.
Moreover, with AI, centralized big data portals could be set up to collate information from plastic surgeons globally to create large databases for interpretation. Such portals could speed up understanding of disease pathogeneses and even infer the best protocols for areas in plastic surgery lacking robust evidence.
AI could also be used to combine anatomical localization and surgical navigation to assist surgeons perioperatively in real-time decision making. It may even assist plastic surgeons to monitor skin wound homeostasis, wound healing and physiological parameters.
The potential uses of AI solutions in reconstructive and plastic surgery are numerous, and Dr. Sina Bari hopes to pioneer these advancements to improve patient outcomes. | 2,936 | 1,401 | 6,096.234118 |
warc | 202143 | Page Length: 10-12 Last Quarterly Update: 10/4/2021 SIC Codes: 2599, 3821, 3841, 3842, 3843 NAICS Codes: 3391
Chapters Include: Industry Overview Trends & Challenges Industry Forecast Quarterly Industry Update Call Prep Questions Website & Media Links Business Challenges Financial Information Glossary & Acronyms
Companies in this industry manufacture medical equipment and supplies, including surgical and medical instruments, dental equipment, ophthalmic goods, and surgical appliances. Major companies include Baxter International, Boston Scientific, Johnson & Johnson, and Stryker (all based in the US), as well as B Braun (Germany), EssilorLuxottica (France), Smith & Nephew (UK), and Terumo (Japan).
Global revenue for medical equipment market is forecast to reach about $670 billion in 2025 at 7% compound annual growth rate (CAGR), according to The Business Research Company. Major markets include the US, Europe, China, India, and Japan.
The US medical equipment and supplies manufacturing industry includes more than 10,000 establishments (single-location companies and units of multi-location companies) with combined annual revenue of about $90 billion.
The industry does not include manufacturing of x-ray or electromedical equipment and devices, such as ultrasound equipment, pacemakers, and electrocardiographs, which is covered in a separate industry profile.
COMPETITIVE LANDSCAPE
As pressure to lower health care costs grows, companies are challenged to create more effective medical equipment while controlling price increases. Consolidation is widespread as larger companies look for economies of scale in manufacturing and R&D. Small companies can compete successfully by specializing in a particular market segment, or through technical innovation. The US industry is concentrated: the 50 largest companies account for about 60% of revenue.
Imports of medical equipment and supplies account for about 40% of the US market; exports represent ...
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warc | 202143 | Sep 01, 2014· Virtually all heavy equipment dealers stock DEF now It comes in sizes from 25-gallon jugs to 330-gallon and larger bulk containers You can also get ,Know More
Maintaining heavy equipment can be a rewarding career for those with mechanical skills Read on to learn about the education requirements and job prospects for a career in heavy equipment maintenanceKnow More
3 Vehicle and Equipment Maintenance Maintain all vehicles and heavy equipment Inspect frequently for leaks Conduct all vehicle/equipment maintenance and refueling at one location - away from storm drains Perform major maintenance, repair jobs off-site Designate a washing site where water drains to the sewer systemKnow More
Summary Report for: 49-907100 - Maintenance and Repair Workers, General Perform work involving the skills of two or more maintenance or craft occupations to keep machines, mechanical equipment, or the structure of an establishment in repairKnow More
Apr 01, 2019· These workers monitor equipment to diagnose problems, inspect equipment to identify damage, and disassemble and reassemble machinery Maintenance workers require specialized training and on-the-job experience to learn how to do their jobs properly The most common causes of death for maintenance workers are contact with equipment 11Know More
We found that the maintenance cycles were not frequent enough I offered to complete a maintenance plan that would be followed carefully for 90 days This plan ended up being implemented permanently because it decreased our breakdowns by 43%"36 As a Heavy Equipment Operator, you will be asked to work a variety of shiftsKnow More
The degree of detail to include in your company's program regarding equipment maintenance will depend on the kinds of tools/equipment used Some construction equipment (cranes) have very specific inspection and maintenance requirements Mobile heavy equipment (dozers, loaders, scrapers) may have different maintenance requirementsKnow More
Dec 11, 2017· Problems cost money, and regular maintenance can prevent many problems MacAllister Machinery offers equipment management services to help prevent things from breaking or going wrong It can be a help to fleet owners and managers to offload the maintenance tasks and not worry about what changes and inspections are due for which machinKnow More
With the right approach much more detail will be disclosed on future problems Establishing this theory may take more time if you are unfamiliar with the system or equipment But in the process it should be asked, “Did the problem develop from a lack of preventative maintenance, an operator error, or incorrect use of equipment?”Know More
An example is an $80,000 machine that requires approximately $24,000 in maintenance and repair costs during 5,000 operating hours By implementing sound preventive maintenance tips, this maintenance cost drops by 25 percent to $18,000 8 Simple Steps to Maximize Heavy Equipment Machine LifeKnow More
Module 1: Heavy Equipment Basics The use of heavy equipment is an important part of residential, commercial, and roadway construction and maintenance operations A variety of heavy equipment are used in construction and maintenance Types of Heavy Equipment Heavy equipment can be classified into the following categories based on the type of .Know More
Maintenance carried out at predetermined intervals or according to prescribed criteria, aimed at reducing the failure risk or performance degradation of the equipment The maintenance cycles are planned according to the need to take the device out of service The incidence of operating faults is reducedKnow More
Heavy Equipment Hazards The use of heavy equipment on a jobsite is vital and necessary to the overall success of the construction project However, unauthorized or unwise use of heavy equipment can result in personal injury, loss of life, or severe loss to materials needed to complete the projectKnow More
Equipment Maintenance: An Effective Aspect Of Enhancing Construction Project Profitability 1,Tsado , heavy equipment especially in road construction (Tatum et al, 2006) In 2011, Cucu stated that construction business , Construction firms are often faced with problems related to high rate of equipment failure or breakdown andKnow More
Nov 06, 2019· ENGINES - HEAVY EQUIPMENT - TECHNOLOGY AND MORE, Wednesday, November 6, 2019 Oil Analisys - Common Problems in Multiple Compartments: at November 06, 2019 Email This BlogThis! Share to Twitter Share to Facebook Share to Pinterest , 950F Series II Wheel Loader: Brake Maintenance;Know More
Heavy equipment or earth moving machines have been recently reported due to multiple accidents and fataliti It is a must that all operators have identifiable and verifiable training on the equipment before operating Accidents can happen to both the newly trained and seasoned veterans Tips to Avoid Equipment Accidents For everyone’s safety especially those of the operators, here are ten .Know More
Sample Maintenance Audit Reportdocx Your Company Name Page 1 of 19 Sample Maintenance Audit Report NOTES: 10 This sample maintenance audit report and contents is indicative of the coverage and approach taken by Lifetime Reliability Solutions Consultants when performing a maintenance auditKnow More
CARE notes abuse of the finished roof as one of the nine most common problems plaguing single-ply systems, stating, “Heavy construction traffic can cause scrapes/cuts in the membrane and damage to the underlying substrate In addition to leaks, this can cause premature problems with the roof membrane and may void the guarantee”Know More
Start studying facilities management chapter #1 Learn vocabulary, terms, and more with flashcards, games, and other study tools , and replacement and renovations of building components and heavy equipment , makes it necessary to shut down groups of rooms above and below allocation with a water system problem to perform needed maintenanceKnow More
Preventive maintenance is defined as the regular performance of equipment maintenance practices in order to avoid future equipment problems An important first step in any preventive maintenance program is learning to identify the causes of equipment failureKnow More
Heavy Equipment Maintenance and Repair NOCTI Job Ready Assessment (Continued on the following page) NOCTI performance assessments allow individuals to demonstrate their acquired skills by completing actual jobs using the tools, materials, machines, and equipment relatedKnow More
The main purpose of regular maintenance is to ensure that all equipment required for production is operating at 100% efficiency at all tim Through short daily inspections, cleaning, lubricating, and making minor adjustments, minor problems can be detected and corrected before they become a major problem that can shut down a production lineKnow More
Jun 26, 2019· Cause #2: Failure to perform preventive maintenance Most equipment requires regular maintenance for optimal performance, but too often, preventive maintenance is the first task to go when you’re short-staffed and overwhelmed It’s easy to brush off regular maintenance when things seem to be running just fine, and many companies work under the assumption that experienced workers will .Know More
Nov 29, 2013· Hydraulic Power Equipment - 7 Common Issues On November 29, 2013 in General by Lyndsey Nash After years of working in and supplying to the hydraulic power industry, we have accumulated extensive knowledge and experience of how hydraulic units work, what can go right and of course what can go wrongKnow More
The most common cause for this type of crack is poor drainage conditions and lack of support at the pavement edge As a result underlying base materials settle and become weakened Heavy vegetation along the pavement edge and heavy traffic can also be the instigator of edge crackingKnow More
By the same token, having a breaker that can handle some aspects of maintenance on its own can create a more profitable situation "Automatic" is a big-time buzzword for today's equipment Anything the equipment can do by itself to take another task out of the operator's hands should minimize downtime and increase overall productivityKnow More
Best Maintenance Repair Practices A number of surveys conducted in industries throughout the United States have found that 70% of equipment failures are self-induced Maintenance personnel who are not following what is termed ‘Best Maintenance Repair Practices’ substantially affect these failurKnow More
• techniques and procedures of heavy equipment maintenance and repair using electronic diagnostic equipment • aircraft rescue and firefighting (ARFF) practices while at an airport duty station • federal regulations regarding performance standards and specifications of ARFF equipment ,Know More
These are generally installed on forklifts, excavators, tractors, and other heavy-duty equipment These systems typically experience problems during extreme weather conditions that can affect the performance of fluids They are also prone to problems between the drive shaft and the transmission itself 3 Common Hydrodynamic System ProblemsKnow More
Predictive Equipment Maintenance Oil Analysis Handbook , Oil Analysis Handbook for Predictive Equipment Maintenance Common oil analysis parameters for engines and rotating machines such as turbines, and gearboxes , Oil mix up is one of the most common lubrication problems contributing to machine failure Putting theKnow More | 9,631 | 4,255 | 21,518.664395 |
warc | 202143 | There are many deductions which may help to lower your tax, I’ve listed several that you may qualify for depending on your own situation. I’ve also provided links where you can find additional information. I hope you find this helpful.What Is a Tax Credit?Subtract tax credits from the amount of tax you owe. There are two types of tax credits:A nonrefundable tax credit means you get a refund only up to the amount you owe.A refundable tax credit means you get a refund, even if it's more than what you owe.What Is a Tax Deduction?Subtract tax deductions from your income before you figure the amount of tax you owe.Business TaxpayersFind credits and deductions for businessesCredits for IndividualsFamily and Dependent CreditsIncome and Savings CreditsHomeowner CreditsHealth Care CreditsEducation CreditsDeductions for IndividualsWork Related DeductionsItemized DeductionsEducation DeductionsHealth Care DeductionsInvestment Related DeductionsRE: Deductions for IndividualsTaxpayers may deduct contributions made to retirement plans. But, you need to understand the difference between two retirement plan categories.A Simplified Employee Pension (SEP) plan is for self-employed people.An Individual Retirement Account (IRA) is available to both employees and self-employed workers.When you contribute after-tax dollars into these plans, your contribution is tax deductible.Student Loan Interest: in the 2021 tax year, if you’re not “married filing separately,” you can deduct up to $2,500 in interest on qualified student loans.Educator Expenses: Many educators pay for school supplies and equipment out of their own pockets.For tax year 2021. you can deduct up to $250 of the qualified expenses that you paid during the year. If your expenses are more than $250, you may be able to deduct the higher amount as an unreimbursed employee expense on Form 1040, Schedule A.To be eligible for this deduction, you must be a K-12 teacher, counselor, principal, or aide. You also must work at least 900 hours during a school year.Qualified expenses include:Professional development course feesBooksSuppliesComputer hardware or softwareItemized Deductions: Page 2 of Form 1040 asks you to take the standard deduction or to compute your itemized deductions.The standard deduction for 2021 is $12,000 for individuals and $24,000 for married couples filing jointly.Always use Schedule A and calculate your total itemized deductions. Take the higher amount if itemized deductions are greater than the standard deduction.Here are some itemized deductions that you should take:Casualty and Theft LossesCasualty and theft losses are losses due to:TheftVandalismFiresStormsCar accidentsAs of 2021. you can deduct the dollar amount of the loss over $100. If you have more than one loss, you deduct $100 from the dollar amount of each loss to calculate the tax deduction. You also subtract any funds received from an insurance policy claim.Charitable Contributions: This deduction may be the most difficult to track if you make dozens of small donations throughout the year. Keep a log of the donations you make in cash, and document the checks that you write to a charity.If you donate clothing or other items, ask the charity to give you a written receipt.Donations above a certain dollar amount require a letter from the charity for tax documentation purposes, and the dollar amount changes frequently.Home Mortgage Interest: The tax deductibility of home mortgage interest can have a huge impact on your tax bill.The IRS allows you to deduct interest on mortgage loans used to buy, build, or improve your home.To deduct the interest, mortgages taken out before December 15, 2021 cannot exceed $1 million for married couples filing jointly or $500,000 for married taxpayers filing separately.Our friends at TurboTax have written a great F.A.Q about deducting home mortgage interest that is well worth the read.Medical and Dental Expenses: If the total amount of your medical and dental expenses exceeds 7.5% of your AGI, you may deduct them on your Schedule A .If your total expenses are below the 7.5% floor, they are not deductible at all.Keeping track of this deduction during the tax year can be challenging. If you have a large medical bill in a given year, you’re likely distracted.This deduction is a good reason to find a CPA to help you with your tax return. A tax professional can ask the right questions to help you maximize your deductions.State and Local Taxes: This tax deduction is particularly important if you live in a state with a high state tax rate.You can deduct state and local income taxes on Schedule A of your federal return. But federal contributions such as Social Security, Medicare, or Federal Unemployment are ineligible.401(k) Matching Contributions: This isn’t a deduction but rather a tax strategy that’ll have a long-term impact on your retirement.Many employer-sponsored retirement plans offer an employer matching contribution to your 401(k). If your employer offers a matching contribution, take full advantage of the benefit.Here’s an example. Assume that your company offers a 3% match on 401(k) retirement plan contributions. You decide to contribute 3% of your annual salary, or $1,800. These are pre-tax dollars, meaning that 100% of the $1,800 you earn is invested.Since you contributed 3%, your employer invests another $1,800. You now have $3,600 invested, and you don’t pay taxes on the earnings until you start to withdraw funds in retirement.It may be the most valuable tax strategy available to you.Keep Detailed Records: Preparing to file your taxes can be time-consuming, but getting the most out of your available tax deductions will save you money. Use these tips and keep detailed records during the tax year. Consider working with an experienced tax preparer who can help you file your taxes accurately.RE:10 Tax Deductions You Should Take In 2021 - QuickBooks20 popular tax deductions and tax credits for individualsThere are hundreds of deductions and credits out there. Here’s a drop-down list of some common ones, as well as links to other content that will help you learn more.Student loan interest deductionAmerican Opportunity Tax CreditLifetime Learning CreditChild and dependent care tax creditChild tax creditAdoption creditEarned Income Tax CreditCharitable donations deductionMedical expenses deductionDeduction for state and local taxesMortgage interest deductionGambling loss deductionIRA contributions deduction401(k) contributions deductionSaver’s CreditHealth Savings Account contributions deductionSelf-employment expenses deductionHome office deductionEducator expenses deductionResidential energy creditRE:Tax Deductions Guide and 20 Popular Breaks for 2021 - NerdWallet1. Charitable Donations: Donations to a qualified charitable organization are deductible (qualified organizations should be able to give you proof of status). Make sure that you can supply all necessary receipts or acknowledgement letters to the IRS. If you receive any goods or services in exchange, subtract the value of the goods and services from the contribution amount.For tax year 2021. you may deduct donations worth up to 50% of your income. Starting next year, this cap will be raised to 60% per the TCJA. The new law eliminates your ability to deduct donations made to a college in exchange for the right to buy athletic tickets.2. Medical and Dental Expenses: You can deduct the amount of your unreimbursed medical and dental expenses that exceeds 7.5% of your Adjusted Gross Income (AGI). For example, if your AGI is $50,000, you may deduct the portion of your medical expenses over $3,750. Under the TCJA, this threshold will increase to 10% of your AGI in tax year 2019.3. Performing Artist Expenses: Are you the stereotypical starving artist? Certain unreimbursed business expenses of performing artists, as well as reservists and fee-basis government officials, are handled separately from other deductible business expenses. See the instructions for Form 2106, "Employee Business Expenses," for details. This tax season is the last time you will be able to claim this deduction, as it has been eliminated completely under the TCJA.4. Tax Preparation Fees: Generally, you can deduct fees that you pay for tax preparation in that year. This means that on your 2021 return, you can deduct the fees incurred in 2021 for preparing your 2021 return. Fees for tax preparation software, tax publications, and electronic filing fees are all included, but the TCJA has also eliminated this deduction starting in tax year 2018.5. Mortgage Interest, Points, and Insurance: The mortgage interest that you pay on your home, as well as a portion of the points you paid to reduce your interest rate, may be deductible if you meet the criteria listed in IRS Publication 936, "Home Interest Mortgage Deduction." This applies to mortgage debt of up to $1 million for home loans taken before December 15, 2021. and mortgages of up to $750,000 taken after that date. Mortgage insurance premiums also qualify under the mortgage interest deduction through tax year 2021. but they are subject to phase-out beginning at $100,000 AGI (for married filing jointly status).6. Home Equity Loans: Interest on home equity debt of up to $100,000 may be deducted in 2021. For next year, experts say interest on HELOCs should still be deductible provided that homeowners use the proceeds of the loan to make home improvements, and the first mortgage balance plus the HELOC does not exceed $750,000.7. Gambling Losses: Was it a bad year for you at the racetrack but a good year with lottery tickets? Believe it or not, you can deduct gambling losses with sufficient documentation ‡ but only to the extent that you offset other gambling winnings.8. Real Estate and Personal Property Taxes: Generally, taxes that are levied through home ownership, such as real estate taxes are deductible.9. State/Local Taxes: You can deduct your state and local taxes paid in the previous year, or you can deduct the sales taxes that you paid (preferable for states that levy no state income tax). If you choose to deduct sales taxes, consult the 2021 Schedule A instructions to get a baseline value and then add the tax on big-ticket items that were purchased during 2017.Despite attempts to eliminate this deduction, the TCJA keeps it in place, but limits the total deductible amount of income, sales, and property taxes to $10,000, beginning in tax year 2018.10. Job-Hunting Expenses: If you are looking for a new job within your present occupation and meet other criteria in IRS Publication 529, "Miscellaneous Deductions," you may deduct certain job-hunting expenses such as fees to employment agencies, even if you don't get a new job. Good luck with the job hunt, because thanks to the TCJA, you won't be able to deduct these expenses going forward.NOTE: The following deductions have even greater value, as they are "above the line" deductions. These deductions are subtracted off your AGI directly and are available to you whether or not you itemize.11. Moving Expenses: If you succeeded in the above job hunt and must move because your new job is at least fifty more miles away from your current home, you can deduct some moving expenses. See Publication 521, "Moving Expenses," for details. The TCJA eliminates this deduction for the 2018-2021 tax years.12. Retirement Plan Contributions: Contributions to tax-deferred retirement accounts may be deductible. Roth IRAs are not since they are funded with post-tax dollars. This deduction has been kept in place by the TCJA.13. Alimony: Amounts that you pay to a former spouse, excluding child support payments, may be deductible. See Tax Topic 452 for details. The alimony deduction remains in effect through 2021. but disappears for couples divorced in 2021 or after.14. Health Savings Account Deductions: Your 2021 contributions to your Health Savings Account (HSA) are deductible, although employer contributions are not. To qualify, you must be covered by a high deductible health plan (HDHP) and have no other health coverage, except certain permitted coverage.15. Self-Employment Expenses: As a self-employed person, you pay both the employer and employee component of payroll taxes. Fortunately, you get to deduct the 50% considered the employer portion. In some cases, you can also deduct retirement fund and health insurance expenses.16. Home Office Deduction: You may be able to deduct some expenses for the business use of your home if there is a part of it that you use regularly and exclusively for work. To qualify, your home should also be your principal place of business, so even daycare providers may take this deduction. Refer to IRS Publication 587, "Business Use of Your Home" for details on how to calculate your deduction.17. Educator Expenses: K-12 educators can deduct up to $250 in qualified and unreimbursed educational expenses. These can be items used in the classroom or payments for professional development courses taken within your field. The TCJA has not made any changes to this deduction.18. Educational Deductions: You may be able to claim a deduction on student loan interest paid ‡ but first see if you qualify for educational tax credits such as the American Opportunity Tax Credit and the Lifetime Learning Credit. Tax credits subtract directly and fully from your tax bill, compared to deductions that reduce your tax bill proportionally to your tax rate.RE:18 Top Tax Deductions For 2018 | 13,571 | 5,614 | 32,602.792483 |
warc | 202143 | About the Personal Financial Planning Certificate Program
The SECURE Act is the first major legislation to revamp retirement plans in over a decade. The provisions and planning strategies to help your clients avoid unintended tax consequences on their estate and retirement plans have been implemented into this learning program.
The Personal Financial Planning Certificate Program is a series of certificates covering the core areas of personal financial planning (PFP), including retirement, estate, risk management and insurance, and investment planning, and how tax planning relates to each area. This certificate program is a combination of education and a certificate exam that gives you the opportunity to enhance your knowledge and demonstrate competence in that specific discipline.
This PFP certificate program offers three different options:
Certificate:You can display your competence and understanding in one or more core areas with a digital badge awarded upon completion of each certificate exam, an online proctored exam taken from the convenience of your home or office. This certificate offers optional online education to provide a thorough comprehension of the material in preparation for the exam. Education:If CPE is your goal, you can purchase the education, without the certificate exam, and simply earn CPE credit for your CPA license, PFS credential, and/or CFP® credential. If you hold the PFS credential, there is no need to take the certificate exam because your PFS credential exam tests this material. Credential:If you are an active CPA who wants to obtain the PFS credential, the certificate program provides an alternative pathway for meeting the exam and education requirements. See aicpa.org/pfs for details. The Retirement Planning Certificate Program
The Retirement Planning Certificate Program is an informative and engaging learning experience that will enhance your knowledge in retirement planning. Part of the Personal Financial Planning Certificate Program, this certificate program includes six dynamic courses covering critical steps in the retirement planning life cycle, including unique planning for aging and chronically ill clients.
This certificate includes the following courses: The Retirement Planning Process Governmental and Employer Retirement Plans Personal Retirement Investments, Income, and Expenses Analyzing Client Retirement Data Creating, Implementing, and Monitoring the Retirement Plan Elder and Special Needs Planning CPA, PFS, and CFP Continuing Education
These courses meet the CPE requirements for the CPA license and PFS credential. In addition, it qualifies for CFP board CE credits. The AICPA will report CE credits to the CFP Board every two weeks on a rolling basis as courses are completed. To have your CE reported please complete the following steps as there is not an automated feed to the CFP Board: Send an email to CFPReporting@aicpa-cima.com with the following information: Name, CFP Number, Copy of Certificate of completion and number of CE hours requested to be reported. | 3,073 | 1,356 | 6,932.379794 |
warc | 202143 | Preventing Problems with Slabs on Ground: Thickness, Moisture, and Sulfates
Hosted by World of Concrete 360 and American Society of Concrete Contractors.
What are the characteristics of a concrete slab that can get a contractor in trouble? Some of the most common answers include variations in thickness, excess moisture, and high sulfate soils. At this session, industry experts will discuss solutions to these and other issues with slabs on ground.
What are reasonable tolerances for slab thickness for various types of slabs and how can they be met?
Should tolerances for hard-troweled flat slabs be different than tolerances for sloped and broomed slabs?
How can slab internal moisture levels be achieved within the expected time?
What are the options if moisture remains too high?
What is the effect of using vapor barriers on moisture?
Are vapor barriers sufficient to protect a slab from high sulfate soils or must you attempt to place very low water-cement ratio concrete and find a supplier of Type V cement?
Attendees will hear how industry experts respond to these challenging questions – limited seating so register early and bring your own questions to share during this open forum!
Direct questions to Bill Palmer at bill.palmer@informa.com or 773-494-4619. | 1,288 | 696 | 2,352.08046 |
warc | 202143 | India has one of the largest student populations that clocks in at about 250 million annually. Therefore, the Indian educational system is adopting new technology and processes to provide the best experience possible. One of these methods is to invest in various learning software to conduct online exams in India in a large-scale setting.
Let’s explore how one of the largest student populations pulls off online examinations.
Online Exams in India: Everything You Need to Know Exam Registration
Admissions exams in India are going online. However, this migration poses another problem for most colleges and universities. Their databases don’t have the existing data of all the test-takers, making it difficult to keep track of their progress.
As a turnabout, online cloud-based school management platforms are developed to bridge this gap.
All examinees were tasked to upload all necessary documents online, which makes them readily available for the school’s examination software. On top of that, layers of security are needed before the start of the test proper.
Authentication of the taker’s identity through image and control number is needed.
Online Examination Platform
Like niche school management platforms that focus on school-parent communication, online examination platforms only perform for one purpose. What makes it different, however, is that this niche platform provides at a large scale.
This type of software uses several forms of advanced technology, piecing together a seamless application. First off, it is cloud-based to support several bulk data. Aside from that, it uses a touch of artificial intelligence when it comes to online proctoring.
AI Proctors
Proctoring is necessary for all types of exams, especially the major ones—admissions and assessment examinations. Overseeing hands-on exams is a league of its own, but proctoring online exams is a whole different level.
AI as stand-in proctors standardize the entire process. It sees and processes the activities of all the test takers at the same time. This feat is something that only automation and robots can achieve. It is a much too taxing responsibility to impose on regular people.
Site Restrictions
Aside from AI proctors, online exam platforms have stringent security to keep track of the takers’ web browser activity.
During the scheduled time for the tests, the platform will restrict entry to several possible cheating aids. It usually strikes out social media sites and popular reference sites.
Types of Remote Examinations
This system recognizes the differences in the test-takers access to the internet and capable gadgets. Thus, they introduced two types of remote examinations to accommodate this difference.
Internet-Based Exams
Internet-based exams are for those who have the resources. The takers need to have gadgets and a stable internet connection to access the examination. Students can complete this exam inside the comforts of their homes.
For institutes that offer internet-based exams, they use school management software to organize the whole ordeal. GoSchooler, in particular, has specific tabs that are dedicated to online exams.
GoSchooler‘s portal, as seen above, is only accessible when there is a stable internet connection, making it a stable host for internet-based tests.
Computer-Based Exams
To cater to applicants who don’t have access to the internet and proper device, computer-based exams are organized in specific areas across the country.
Institutions that hold large-scale examinations organize remote examinations where they provide the computer units. These units are enabled to access the exams with the added security configurations.
For these exams, the students or applicants need to travel to their designated test location.
What Exam Types are Supported?
Usually, the type of exam questions is limited when it comes to online exams. But with the availability of online exam platforms in India, it can support various types of questions.
Objective Questions
Objective questions such as multiple choice types and identification items are the most convenient type of questions for online exams.
Online exam platforms can support objective-type questions easily. Evaluation of the entire exam is also quick and easy.
Subjective Questions
On the other hand, test makers avoid including subjective questions in online exams because they are challenging to evaluate and score.
Luckily, the advancements in these online exam platforms support subjective questions, such as essays and tests that require short explanations. In addition, advanced platforms even support and evaluate answers in different languages.
Problem-Solving Questions
Math and logic questions require solutions to see the taker’s complete understanding of the concept.
More often than not, these questions are difficult to translate to online exams. But online exams in India accept scanned answers, especially for these subjects.
Online exam platforms accept and process scanned answers. These platforms can also evaluate the scanned answers to provide an extensive results list after scoring.
Conclusion
Bearing one of the largest student populations in the world, India is on top of the situation to provide convenient online examinations to all its takers.
From online registration to answering and evaluations, online exam platforms made large-scale examinations possible. Online exams in India also support different types of questions that are often avoided by administrators in other countries.
The presence of both internet-based and computer-based online exams is a simple yet smart innovation that makes the process attainable for such a large population. | 5,753 | 2,473 | 13,178.627173 |
warc | 202143 | Pseudomonas aeruginosa is an opportunistic human pathogen that is responsible for nearly 10% of hospital-acquired infections and is the primary cause of morbidity and mortality in cystic fibrosis patients. P. aeruginosa infections have high attributable death rates and are extremely difficult to treat due to widespread antibiotic resistance. Our long-term goal is to understand how this ubiquitous environmental bacterium activates a coordinated virulence program upon introduction into the human host. This information will facilitate the development of therapeutic strategies aimed at inhibiting P. aeruginosa virulence mechanisms. P. aeruginosa possesses a wide variety of virulence factors. The capacity to express many of these factors and to cause disease in an animal model of acute infection depends on the ability of the bacteria to produce the second messenger adenosine 3', 5'-cyclic monophosphate (cAMP). We hypothesize that CyaB, a membrane-anchored adenylate cyclase, initiates a P. aeruginosa virulence program by producing cAMP in response to host cues. CyaB activity is positively regulated by components of the P. aeruginosa Type IV pilus chemotaxis system and negatively regulated by the alginate exopolysaccharide regulatory pathway. In addition, environmental cues including calcium concentration, osmolarity and CO2 substantially affect CyaB-dependent cAMP production. Once produced, cAMP activates a cAMP-dependent transcription factor (Vfr) that controls virulence gene expression. The goal of this proposal is to determine the relationship between structure and function of CyaB and the kinetics of CyaB-dependent cAMP production during infection.
The Specific Aims are as follows: 1) Characterize the structure of the amino-terminal CyaB membrane-anchoring domain (termed MASE2 for Membrane-Associated Sensor-2) and determine its role in CyaB localization, signal detection and catalytic function. Preliminary results indicate that the MASE2 domain is required for enzyme activation. 2) Investigate the mechanism and biological significance of inorganic carbon (bicarbonate and CO2)-stimulated CyaB catalytic activity in vitro and in vivo. CyaB is a member of the inorganic carbon-activated family of adenylate cyclases and the CyaB catalytic domain is stimulated by HCO3- in vitro and by increased extracellular CO2 when expressed in P. aeruginosa. 3) Determine whether CyaB activity is modulated by host cues during infection. CyaB-lacking mutants are attenuated in vivo and CyaB is activated under conditions that mimic the bacterial-host interaction in vitro. We will construct reporter strains to determine if bacterial intracellular cAMP fluctuations occur during cell culture infection and whether cAMP levels change with time and disease progression in a mouse model of acute pneumonia. The bacterium Pseudomonas aeruginosa is a major cause nosocomial infection and is the primary cause of morbidity and mortality in individuals with cystic fibrosis. The prevalence of P. aeruginosa infection in immunocompromised individuals coupled with increasing antibiotic resistance among P. aeruginosa strains represents an urgent public health issue. The goal of this proposal is to define the mechanisms controlling the production of cyclic AMP, a central regulator of P. aeruginosa virulence. This proposal will result in the identification and characterization of novel therapeutic targets in P. aeruginosa as well as other pathogenic bacteria with cAMP-dependent virulence programs.
Marsden, Anne E; Intile, Peter J; Schulmeyer, Kayley H et al. (2016) Vfr Directly Activates exsA Transcription To Regulate Expression of the Pseudomonas aeruginosa Type III Secretion System. J Bacteriol 198:1442-50 Silversmith, Ruth E; Wang, Boya; Fulcher, Nanette B et al. (2016) Phosphoryl Group Flow within the Pseudomonas aeruginosa Pil-Chp Chemosensory System: DIFFERENTIAL FUNCTION OF THE EIGHT PHOSPHOTRANSFERASE AND THREE RECEIVER DOMAINS. J Biol Chem 291:17677-91 Luo, Yun; Zhao, Kun; Baker, Amy E et al. (2015) A hierarchical cascade of second messengers regulates Pseudomonas aeruginosa surface behaviors. MBio 6: Marden, Jeremiah N; Diaz, Manisha R; Walton, William G et al. (2013) An unusual CsrA family member operates in series with RsmA to amplify posttranscriptional responses in Pseudomonas aeruginosa. Proc Natl Acad Sci U S A 110:15055-60 Topal, Hüsnü; Fulcher, Nanette B; Bitterman, Jacob et al. (2012) Crystal structure and regulation mechanisms of the CyaB adenylyl cyclase from the human pathogen Pseudomonas aeruginosa. J Mol Biol 416:271-86 Jones, Adriana K; Fulcher, Nanette B; Balzer, Grant J et al. (2010) Activation of the Pseudomonas aeruginosa AlgU regulon through mucA mutation inhibits cyclic AMP/Vfr signaling. J Bacteriol 192:5709-17 Fuchs, Erin L; Brutinel, Evan D; Klem, Erich R et al. (2010) In vitro and in vivo characterization of the Pseudomonas aeruginosa cyclic AMP (cAMP) phosphodiesterase CpdA, required for cAMP homeostasis and virulence factor regulation. J Bacteriol 192:2779-90 Fulcher, Nanette B; Holliday, Phillip M; Klem, Erich et al. (2010) The Pseudomonas aeruginosa Chp chemosensory system regulates intracellular cAMP levels by modulating adenylate cyclase activity. Mol Microbiol 76:889-904 Orans, Jillian; Johnson, Michael D L; Coggan, Kimberly A et al. (2010) Crystal structure analysis reveals Pseudomonas PilY1 as an essential calcium-dependent regulator of bacterial surface motility. Proc Natl Acad Sci U S A 107:1065-70 Heiniger, Ryan W; Winther-Larsen, Hanne C; Pickles, Raymond J et al. (2010) Infection of human mucosal tissue by Pseudomonas aeruginosa requires sequential and mutually dependent virulence factors and a novel pilus-associated adhesin. Cell Microbiol 12:1158-73
Showing the most recent 10 out of 12 publications | 5,824 | 2,712 | 12,474.784661 |
warc | 202143 | After a divorce it is common for one party to pay maintenance to the other. This is the case if there are children involved but if one partner has been the main earner during the marriage then they may also have to pay spousal maintenance even if there are no children.
Unfortunately the area of maintenance is very murky and often situations arise when there are no exact guidelines. This is why it is crucial that you seek good legal advice from an experienced family lawyer when you are either seeking maintenance or want to stop paying maintenance to your ex-spouse.
Generally speaking when maintenance levels are agreed during the divorce settlement there will be a clause stating that levels may change if there is a change of circumstance. For example, if you receive child maintenance from an ex-spouse and they have a big promotion you can argue that they should now be paying more. Or, if you pay spousal maintenance and your ex-spouse moves in with a new partner with a good salary then you can argue that they no longer need the maintenance that you are paying.
In these cases it often involves going back to the courtroom to come to a new agreement. Before you do so consult with your family lawyer in order to get some idea of the likely outcome of the case and to collect any evidence that you may need of the change in circumstance.
However, it is not just issues with requests for the ex-spouse that we have experience in. Collecting child maintenance payments through the child support agency or the child maintenance service also causes people on both sides of the deal problems. Mistakes are often made by this government service and people can be left feeling bewildered an unsure about their legal rights and requirements.
If this is the case we can help you to work through everything that has happened up to this point and determine whether or not there has been a mistake or an overpayment or underpayment.
Maintenance is not an easy subject to navigate which is why you must seek expert legal advice when you are looking to make any changes so you do not end up losing money. | 2,109 | 992 | 4,466.742944 |
warc | 202143 | Non-Surgical Wrinkle Treatments
Want to rejuvenate your look but you aren’t sure about a surgical treatment? Facial injections and fillers could be an option for you. These non-surgical treatments also allow for minimal side effects and virtually no recovery period.
Reducing Wrinkles With Blockers
Neuromuscular blockers, often referred to as Botox
, Dysport , and Xeomin , are prescription medications that keep muscles from contracting.
Specialists can inject the blockers into your muscles to improve and smooth the appearance of wrinkles caused by your face’s natural expressions, like smiling or laughing. These can include frown lines, forehead lines, and fine lines around the eyes.
You won’t see the full effects of your injections for about a week and peak effects usually show about two weeks after your procedure. Results can last between three and four months depending on where your blockers were injected.
These medications can also be used to treat chronic migraines, excessive sweating of the palms or armpits, jaw tension, and vocal issues, as they block muscles from contracting.
Types of Fillers
Fillers are used for several types of procedures including lip plumping, cheek augmentation, and wrinkle smoothing enhancement.
Lip Fillers
Some fillers are longer lasting than others. If you’re trying lip fillers for the first time, your specialist will likely recommend a temporary filler that lasts for about three months. If you’re looking for something longer-lasting, a filler that will give you results for about one year can be used.
The temporary filler can be dissolved within 30 minutes if you find the plumper isn’t for you. The longer-lasting filler doesn’t allow for that option.
Cheek Fillers
The fillers used for cheek augmentation tend to be long-acting and can be calcium-based. This filler is used for very deep fillings. This type of filler is used for augmentation of a cheekbone, the nasolabial fold, or along the chin line. Depending on the product your surgeon uses, you can expect results to last between one and two years.
Blocker Enhancing Fillers
Fillers are often used in tandem with blockers. As we age we lose collagen and fat from our faces. Wrinkles that were once temporary become permanent, so blockers are no longer enough to completely smooth them.
Fillers are used to puff those permanent wrinkles up, giving you a smoother look overall. If you choose to get fillers, you’ll receive them at a separate appointment following your blocker procedure.
Determining How Much & What Type of Products You Need
During your visit, you and your specialist will discuss what you’d like to change about your face. Each wrinkle needs to be evaluated individually because your specialist needs to determine which type of blocker and how many units to use in each area. The wrong type or amount of blocker can cause problems in other areas of your face.
It’s also important to keep in mind that each individual’s facial muscular structure and bone structure are different, so your specialist will cater your treatment strategy to yours.
Your specialist may offer same-day procedure depending on a few things. If this is your first experience with injectable blockers or fillers, your specialist may encourage you to take some time to think about it.
If you’ve got an ongoing cold or viral infection, your specialist won’t allow you to undergo the procedure for safety reasons.
Facial Injection Procedure & Recovery
These outpatient procedures last about 30 minutes. You can expect some bruising of the face and swelling at injection sites, which will reduce within 20 minutes. You can also use a bit of makeup to cover the bruising after your procedure if you choose.
Recovery for this procedure is minimal. You won’t need prescription pain medication or to take time off of work.
Qualified Facial Plastic Specialists
It’s important for patients to choose an experienced, board-certified facial plastics specialist. Both the type of blockers and fillers and the number of units used are crucial in ensuring your procedure results in the look you want to attain.
Our board-certified specialists have additional training in plastic surgery techniques, often preventing the need for further procedures. Our plastic specialists have both the skill and vision necessary to ensure you can present your best side.
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It would be an understatement to say that 2020 has been challenging. From the COVID-19 pandemic to earthquakes, severe storms, and lockdowns—in addition to everyday life challenges—this year has been incredibly stres...
Body hair—it’s something we spend lots of time, energy, and money on removing. Whether you’re tired of shaving your legs or armpits or pained by waxing that upper lip, laser hair removal may be a good choice for yo... | 5,589 | 2,533 | 12,034.11212 |
warc | 202143 | “Attorney General Lynn Fitch of Mississippi made nationwide news last week when she asked the Supreme Court to overturn its two leading precedents on the right to abortion, Roe v. Wade and Planned Parenthood v. Casey. I was puzzled by the treatment of this filing as news, unless the news was that a state finally came clean with the court and told the justices what it really wanted them to do.”
“Well, that didn’t take long.
Only days after surprising the nation by striking down a strict anti-abortion law in Louisiana, the Supreme Court under Chief Justice John Roberts reminded Americans once again that it is no friend to reproductive rights, or to the vast majority of women who will use some form of birth control in their lifetime.
In a decision Wednesday, the justices dealt another blow to the birth control mandate under the Affordable Care Act. In the wake of the 7-to-2 ruling in Little Sisters of the Poor v. Pennsylvania, “between 70,500 and 126,400 women would immediately lose access to no-cost contraceptive services,” Justice Ruth Bader Ginsburg noted in her dissent, citing a government estimate.
The Little Sisters of the Poor is an order of Catholic nuns who are religiously opposed to birth control. (Many conservatives wrongly conflate some methods of birth control with abortion.) They’re also opposed to the A.C.A.’s birth-control mandate, which says that insurance plans sponsored by large employers must include preventive care — including all forms of birth control approved by the Food and Drug Administration — at no additional cost. That’s why, if women have insurance through work, they probably have not been charged a co-pay to get birth control pills or an intrauterine device in recent years.
The order of nuns — along with other entities, like the company Hobby Lobby, that have taken issue with the contraception mandate — say that it violates their religious liberty under the Religious Freedom Restoration Act, a 1993 federal law. The religious order feels this way despite the fact that religious nonprofits already were able to exempt themselves from the contraception mandate by merely filling out a form. In other words, the Little Sisters of the Poor did not have to pay for a single birth control pill.”
Dec. 19, 2019 at 12:24 p.m. PST
“J.K. Rowling has long used the Internet to tweak the Harry Potter universe she created, surprising fans with trivial revelations from Ron Weasley’s patronus to the fact that wizards used to poop in their robes. But on Thursday, Rowling changed many fans’ views of her own character when she tweeted her support for a woman who was fired over her anti-trans social media posts.
“Dress however you please,” Rowling wrote on Twitter early Thursday. “Call yourself whatever you like. Sleep with any consenting adult who’ll have you. Live your best life in peace and security. But force women out of their jobs for stating that sex is real? #IStandWithMaya #ThisIsNotADrill.”
The woman named in Rowling’s tweet is Maya Forstater, a tax expert who lost her job at a think tank after tweeting that trans women can’t “change” their biological sex. Forstater’s contract as a visiting fellow at the Washington- and London-based nonprofit Center for Global Development was not renewed in March, according to the Guardian, after they found her tweets to be exclusionary toward trans people. On Wednesday, Judge James Tayler at the Central London Employment Tribunal dismissed Forstater’s claims of wrongful termination, per the Guardian, calling her “absolutist in her view of sex” and her expressed beliefs “not worthy of respect in a democratic society.”
Rowling’s tweet triggered backlash almost immediately, attracting condemnation from individual users and organizations alike: “Trans women are women. Trans men are men. Non-binary people are non-binary. CC: JK Rowling,” the Human Rights Campaign account tweeted
. Replying to Rowling’s tweet, one fan wrote
that she grew up reading the Harry Potter series as a trans child, and that the author’s decision “to support people that hate me” brought tears to her eyes.
Rowling’s representatives declined to comment to The Washington Post.”
Source: J.K. Rowling tried to make her work more inclusive. Then she tweeted support for an anti-trans researcher. – The Washington Post | 4,528 | 2,260 | 8,619.228319 |
warc | 202143 | Major job disruption is on the way for self-employed workers as HMRC prepares to press ahead with changes to the way contractors are taxed, under a system known as IR35.
IR35 is a complicated piece of legislation designed to crack down on a tax loophole used by self-employed individuals operating through a company.
From 6 April, all medium-sized and large private businesses have to decide whether contractors working through a company fall inside or outside the IR35 umbrella.
Self-employed workers argue that even if they fall outside the scope of IR35, businesses do not want to risk the financial implications of getting an IR35 judgment wrong.
Workers claim the forthcoming changes have already unnerved some businesses who are offering them the option of staying on under PAYE conditions or leaving entirely.
“The overwhelming trend is that the larger the end client, the more likely they are to have unfair policies,” says James Poyser, head of accountancy firm inniAccounts, who is also lobbying the Government to change the rules.
It has left the future uncertain for some of Britain’s contractors, and many have been in touch with
i.
Below, we reveal their concerns. Most did not want to speak on record for fear of reprisal.
‘I’m very upset’
Emily McVickar (not her real name) will leave her job working in computer system validation for a pharmaceuticals company at the end of February.
She says she is “very upset” about the IR35 changes, which have caused her a great deal of stress.
In August 2019, she received a letter from HMRC which asked her to confirm her IR35 employment status. “It had quite a large impact on my state of mind, and [on] how I interacted with loved ones and friends and family,” she says.
“I ended up having to take time off last year. Some other things happened but that was one of the things that certainly contributed to taking time off. It’s just the stress,” says the 50-year-old, who lives in west London.
Ms McVickar says her company has offered contractors like herself to stay on as PAYE workers but she has turned it down because she is uncomfortable with some of the conditions of the contract relating to holidays and furlough periods. She is also put off by the tax implications of staying on under PAYE conditions, which would affect her salary.
“I like working where I work. I don’t want to leave but I don’t feel I have a choice because I can’t deal with the stress if I stay on the contract they’ve offered, even if the money was good with regards to the National Insurance contributions… I’d still feel I couldn’t stay on.”
HMRC has said it “will not carry out targeted campaigns into previous years when individuals start paying employment taxes under IR35 for the first time” upon or after 6 April 2020, but this has done little to reassure Ms McVickar. “I don’t believe it, they could change their mind. It’s easy pickings for money.”
She has no immediate plans to find a job. “I’m going to sit on the bench and see what happens really. I’ve got some personal stuff I want to do but I’m not immediately looking for a new contract straight away.”
Read more:
Banks will ‘no longer use contractors’
Others are considering shutting down their limited companies altogether because of the IR35 changes.
Gary Jones (not his real name), who is a business analyst for a global European investment bank in the City of London, believes many banks are now wary of hiring contractors like him.
“Since HSBC [said it] was not going to entertain limited companies, that has basically rippled through the whole City. There is not a single bank that I have seen that is advertising outside IR35 contracts. I look on the contract work boards, internet boards, they are all saying PAYE, inside IR35 roles,” he claims. “Or else it’s permanent.”
Mr Jones, from north Essex, has been told his bank will no longer use contractors. He plans to accept a time-limited PAYE contract but is “incredibly irritated and frustrated” by the position he finds himself in.
“I chose to be a contractor because I like the flexibility of work, I like to pick and choose the projects I do. And by and large that has been very successful – I’ve done it since 2004.”
While he admits there are downsides, such as having to pay someone to do his accounting and having to provide for his own pension, the tax implications of a PAYE contract will cut his income by up to 30 per cent, he predicts.
“You can’t get outside IR35 contract work in my industry any more… So I have to fold my limited company or leave it running and not push any business through it.”
‘A massive overhaul of an industry’
Some contractors, like 52-year-old Paul Green (not his real name), feel the only way they can deal with the damaging impact of IR35 may be to move to another country where they believe their skills will be more valued.
“No choice, pure and simple. My only choice. Canada is favourite. Sell the house. Buy one twice the size with no mortgage in Nova Scotia. My skills are recognised, low crime, progressive society,” says the licensed aircraft engineer, who is working for an airline.
Mr Green, from Kent, says the airline is imposing a ban on contractors operating through private companies. In the short-term he plans to take permanent employment but will eventually look to relocate abroad.
He has also been offered work away from home with a contract worth £60,000 through an umbrella company with another airline. Umbrella companies employ contractors and provide a payroll service. But, after tax, he does not believe his take-home pay would be enough to support his family’s current life or the costs associated with working away from home.
After a change in personal circumstances, Mr Green took voluntary redundancy in 2016 as he thought the “good money” he could make as a contractual aircraft engineer would make up for the lack of benefits.
“My turnover is around £80,000 compared to a permanent employee who gets around £57,000,” he says of his current situation.
“They get 34 days of holiday. Last year I took seven.
“They get [a] company pension contribution. I get none. They get staff travel, clubs, corporate benefits, share schemes and employment protection. I get accountancy fees, public liability insurance and buying tools and workwear.
“I’m absolutely livid [about the IR35 changes]. I’ve spent 34 years learning what I do. I’m very experienced. I can call the shots. I have got to the point in my life where I can earn a decent amount of money.”
He cannot get his head around the decision to widen the scope of the IR35 rules.
“Everything I have worked for 34 years has gone… A change like this can result in a massive overhaul of an industry,” he adds. | 7,089 | 3,279 | 14,461.21409 |
warc | 202143 | Well, perhaps not defeat him, but your dog could repel his unwanted advances...
The legend around Vampires being adverse to Garlic does have basis in fact: many bloodsucking parasites such as fleas, mosquitoes and ambulance-chasing lawyers hate the taste and smell of garlic.
So if you're not worried about the smell of garlic, slipping some capsules into your dog's dinner can have a beneficial effect on keeping those small unwanted guests away. If you are worried about the smell, you can get odourless capsules - but they may be less effective.
Of course, with the advent of Vampires who sparkle in the sunlight, write love letters and moodily mope about instead of being thoroughly evil and giving people uninvited love-bites, perhaps the idea of warding off vampires isn't as alluring to those more used to modern vampire stories...
But, if you're walking your dog through a creepy graveyard and you feel there's a spooky presence, you can rest assured that a natural remedy will keep your dog from becoming one of the bloodsucking undead.
Unfortunately, it does nothing to ward off Zombies... sorry. 🙁 | 1,126 | 635 | 1,964.737008 |
warc | 202143 | Commitments and Contingencies 12 Months Ended
Jun. 30, 2021
Commitments and Contingencies [Abstract] Commitments and Contingencies
COVID-19
As a result of the pandemic, the Company has at times experienced reduced capacity to provide CDMO services as a result of instituting social distancing at work procedures in our Texas facility, restricting access to essential workers, as well as taking other precautions. The Company also experienced a full three-day operational shutdown in April 2020 for extensive facility cleaning following the discovery that an employee had contracted COVID-19, and successfully resumed operations on a reduced capacity basis.
The Company has ascertained that certain risks associated with further COVID-19 developments may adversely impact its operations and liquidity, and its business and share price may also be affected by the COVID-19 pandemic. However, the Company does not anticipate any significant threat to its operations at this point in time. Due to the general unknown nature surrounding the crisis, the Company cannot reasonably estimate the potential for any future impacts on its operations or liquidity.
The outbreak and spread of COVID-19 and continued progress in various countries around the world, including the United States, has led authorities around the globe to take various extraordinary measures to stem the spread of the disease, such as emergency travel and transportation restrictions, school closures, quarantines and social distancing measures. The outbreak of COVID-19 has had an adverse effect on global markets and may continue to affect the economy in the United States and globally, especially if new strains of SARS-CoV2 emerge.
Agreements
Lease – Bryan, Texas
As discussed above, iBio CDMO is leasing its facility in Bryan, Texas from the Second Eastern Affiliate under the Sublease. See Note 14 – Finance Lease Obligation for more details of the Sublease.
Planet Biotechnologies
On August 27, 2020, the Company entered into an exclusive worldwide license agreement with Planet Biotechnology Inc. (“Planet”) for the development of Planet’s COVID-19 therapeutic candidate, ACE2-Fc. The Company made a one-time up-front payment of $150,000 on September 11, 2020.
After reviewing our internal strategy, the Company decided to terminate the partnership with Planet for the development of the recombinant ACE2-Fc protein as treatment for COVID-19 and other coronavirus diseases. As part of the original agreement, the Company will not have anything due to Planet at the time of termination. See Note 10 – Intangible Assets with regards to the impairment of intangibles related to termination of the agreement.
X
X
- Definition
+ References
The entire disclosure for commitments and contingencies.
+ Details
Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef | 2,879 | 1,413 | 5,762.075018 |
warc | 202143 | 1. Movement Of The Body, Stillness of The Mind
I first encountered this great signal when I studied movement through Ido Portal in 2017-2018. It is such a great message.
Since we are not brains in a jar, our creativity and intellectual outcomes are pretty much dependent on our ability to move our bodies.
In the book "Stillness is the key" Ryan Holiday explains how the body is a key domain to achieve true stillness. Not being physically still but being mentally present and aligned with your own state of mind. Free from distractions, worries, maladies and wrong behaviors.
I find the life of Winston Churchill inspiring even though I would not like to have such a busy schedule as he had. He lived a very productive but also a creative one. He did not only have a key role to save Europe and rest of the World from The 3rd Reich expansion. He was also a prolific writer and painter. On top of this he realised the benefits of physical work, starting off a parallel path of becoming an amateur bricklayer.
It is not about adding more and commit to more.
It is about creating outlets and use your physical body to grow in your profession and daily life. 2. Think Like A Kid
How can we possibly explore new things if we are not curious and ask questions?
Avi Loeb, an american-israeli physicist would rather be surrounded with youthful curious learners that dare asking lots of questions than an expert with a bias attached to his/her own experience. The interesting here is that he encourage a behavior which is rare in his own profession and domain.
Youthful curiosity is a compelling model for creative research.
Many scientists are focused on academic ego boosts and misses the true essence of scientific learnings and curiosity.
In episode 154 of Lex Fridmans podcast he discusses this and much more, if you are curious about physics, astronomy and life in the universe.
3. The Antilibrary
I got so happy when I read this blog post by Farnam Street: The Antilibrary.
The main point?
Let your library serve you as a visual reminder of what you don’t know.
I used to get lots of advice on the fact that you should first finish the books on your bookshelf before you buy, borrow or start reading another book.
The last couple of years I have been spending more and more money and time ordering books and building up my library. The speed of added books in the library is higher than I possibly can finish them. My guilty conscience starts to grow and my wife starts to get suspicious on where all the money goes every month.
Now I have a different view on it and seeing my library as a pulling force into future learning journeys.
Your library is not an intellectual status signal. It is a haven for future learning.
For more in depth insights on the relationship around books and knowledge you can read The Black Swan, by Nassim Taleb.
Actually the whole Incerto Series is pretty eyeopening and a must read for any curious learner.
Thanks for reading and until next string:
stay curious, stay nimble.
P.S I have been starting to curate a playlist I listen to when writing my newsletters. I hope you enjoy it 🎶 🎧 D.S
 Maildrops & articles
Join the group to receive the latest updates in your inbox. | 3,264 | 1,697 | 6,158.708309 |
warc | 202143 | On June 5
th 1981 the United States Centres for Disease Control published a report about a new disease that was hitting gay men. That report ushered in the AIDS era. Twenty one years have passed since then, years in which the disease has grown to nightmarish proportions, with almost every passing year seeing the need to revise upwards already dire estimates and projections. In 1991, the World Health Organisation expectation was that by the year 2000 HIV infections worldwide would amount to some 20 million. The projection was almost three times short of the mark. Since the epidemic began, more than 60 million have been infected with the virus, at least 20 million have died of the disease, and a conservative estimate is that presently some 40 million people are living with HIV/AIDS.
Currently there is no known cure for HIV or AIDS. Work on the development of a vaccine is proceeding, but
none is yet available and the likelihood seems to be that ten years or more will pass before a universally available, affordable and easily applied vaccine comes on to the market. Drugs that hold HIV in abeyance are available, but even with the substantial price reductions that have been effected in the past year, their cost remains very high, their administration requires a well-developed health infrastructure of the kind that several countries do not have, and there are growing concerns about the development of HIV strains that are resistant to the drugs currently in use. Excessive reliance on controlling the epidemic through the provision of antiretroviral therapy for infected individuals also faces massive annual cost increases, since new numbers will be added each year to the ranks of those whose lives are being prolonged by a therapy which must be maintained throughout life.
In this set of circumstances, preventing the further transmission of HIV must be the principal strategy. In its turn, prevention depends very heavily on education. A little reflection will show how every prevention effort, the majority of coping
strategies, much of the activity directed towards the mitigation of impacts, and virtually every programme designed to outwit and get ahead of HIV/AIDS, depends in one way or another on education. It is no exaggeration to say that in the current state of scientific knowledge and development, the only protection available to society lies with the “social vaccine of education”.
In addition to its saliency as a constitutive element of every information, education, and communication (IEC) approach, formal and non-formal education “offer a window of hope
unlike any others for escaping the grip of HIV/AIDS” (World Bank, 2002, p. 2). There are several reasons for saying so: Education, and above all school education, has been shown to be related to the reduction of HIV prevalence rates among young people. Uganda and Zambia have both experienced dramatic declines in the infection rates of the sub-group of 1519 year-old girls with secondary school education, and in Zambia it has been found that a girl who has dropped out of school is three times more likely to be HIV infected than an age-mate who remained in school (Fylkesnes et al., 2001). The precise mechanisms by which education contributes to this change are not yet clearly understood, but they may lie in a combination of enhanced ability to use information, the package of habits and dispositions that learners accumulate throughout their schooldays, the way school education opens one up to future prospects, and the increased opportunities it provides for economic independence (Coombe & Kelly, 2001). Formal school education reaches the majority of young people in a country. Further, it reaches them at an early age when they are in their most formative years. Therefore it has the potential to transmit significantly important HIV prevention and other AIDS-related messages to young people when they are in their most receptive developmental stage. size=”2″>School education is among the most powerful tools for transforming the poverty and gender inequality environment in which HIV/AIDS flourishes. It is universally acknowledged that growth out of poverty and growth in education are almost synonymous. Likewise, the education of both boys and girls contributes significantly to the evolution within a society of an environment where there is less acceptance of gender inequality and female disempowerment. Girls who remain longer in school tend to commence sexual activity at a later age, are more likely to require male partners to use condoms, and marry at a later age (World Bank, 2002). Each of these factors contributes to the reduction of HIV transmission.
But education, especially school education, can play an even more crucial role in the combat with HIV/AIDS. Already doing well, it can do even
better. Enhancing the contribution that education can make to reducing the likelihood of HIV transmission and managing the impacts of the disease requires attention to the following issues: Expand Access and Improve the Quality of Provision
size=”2″>Education in the sense of schooling can do nothing to reduce the transmission and impact of HIV/AIDS for children whofor whatever reasoncannot enrol in school. Neither can it promote the knowledge, understanding and attitudes that are fundamental to the reduction of
HIV transmission if the quality is so poor that real and meaningful learning achievement does not occur.
Hence the AIDS epidemic underscores the crucial importance of attaining the International Millennium Development Goals that relate to Education-For-All (EFA).
These are
“Full speed ahead on EFA goals is vital.
A general basic educationand not merely instruction on preventionis among the strongest weapons against the HIV/AIDS epidemic.
An urgent, strategic, and education-centred response
is of the utmost importance” (World
Bank, 2002, p. 6).
It is also important to take steps that will enable children, especially girls, continue in school to the secondary level. What is gained at this level appears to make a crucial difference to the protection of oneself and ones potential
partner against HIV infection. Expanded access to secondary education also provides a surer route out of poverty, at both individual and national levels, and through this mechanism provides a more comprehensive defence against HIV transmission. Mainstream HIV/AIDS into Every Aspect of Education
The potential of HIV/AIDS to devastate the lives of individuals, the economies of countries, and education systems themselves, is too great for the disease and its consequences to be merely bolted on as some
additional consideration within the programmes of already over-worked education ministries, departments and institutions. This is the most devastating disease that humanity has ever experienced. Responding to it is not an optional extra, but must be an integral and accountable part of concerns and programmes at all levels, from the office of the Minister down to the humblest village school.
Accentuating the importance of this mainstreaming is the fact that HIV/AIDS places the entire education system and all its institution under profound threat. An
education system that does not mainstream HIV/AIDS into every facet of its operations runs the risk of being overwhelmed by the epidemic and the variety of its impacts. It can become so weakened by the epidemic (through the loss of educators, impairment of quality, numerous negative effects on learners, educators and managers, and constraints on resources) that its ability to provide both general education and HIV/AIDS education could be greatly reduced. In the absence of mainstreaming, the one system that has the potential to provide crucial HIV protection to society could find that it was unable to do so because it was itself besieged by a network of interrelated, debilitating, and complex AIDS-related problems.
A practical aspect of this mainstreaming is to ensure that education policies, procedures and regulations are reformulated to take
account of HIV/AIDS. It will also be necessary to incorporate HIV/AIDS issues into every aspect of an education ministrys strategic planning process. In severely affected countries, mainstreaming HIV/AIDS will also necessitate dedicated structural arrangements, involving full-time staff possessing considerable authority and backed up with adequate human, financial and material resources, who will maintain the momentum for progress in everything that relates to the interaction between the disease and the education sector. Establish Programmes and Activities that Run along a Continuum from Prevention to Care
At the sectoral level, provision must be made for programmes that respond to the prevention needs of employees. If the system is to function, all categories of education staff must
know about the disease and how to protect themselves against it. This calls for programmes that address HIV/AIDS in the workplace. At the institutional level, there is need for specific prevention education programmes that teach about HIV/AIDS and such related areas as reproductive health (see below).
Realisation is growing that responding to the care and treatment needs of those infected with HIV/AIDS is an essential complement to prevention efforts. There is also growing recognition of the need for attention to the management and mitigation of
impacts. Aspects that are of particular relevance to the education sector include responding to the needs of the exponentially increasing number of orphans, catering for learners, educators and education employees who are HIV infected or whose condition has progressed to AIDS, reaching out to and providing support for infected persons in communities, especially those who are relatives of school personnel, and establishing schools as multipurpose welfare and development centres within affected communities. Engage Creatively with Others
In the past the cardinal error was made of treating HIV/AIDS as being primarily a health problem. To treat it as being primarily a problem for education would be to repeat and compound the error. HIV/AIDS is wider than any sector, but touches the entire range of
development and human welfare interests. Responding to it likewise demands the widespread participation and interaction of players from various areas of the public sector, as well as the involvement of the numerous organs of civil society. The walls of territoriality that government ministries/departments build for themselves and that the government sector sometimes uses to effect the marginalisation of NGOs, faith-based communities, community-based organisations, business coalitions, and other partners, must be broken down. It is paramount that in the struggle with HIV/AIDS the education sector manifest the fullest cooperation, sharing of resources and facilities, and collaboration in programme design, implementation and evaluation, with these and other potential partners. The problem of AIDS is too large for the sector or any of its partners to deal with on their own. But working together they can succeed in bringing it to heel. | 11,216 | 4,892 | 25,522.590352 |
warc | 202143 | Whether it’s Godzilla, Barney, or Jurassic World, the world seems to have a soft spot for our ancient reptiles, and why not? They are majestic, mighty, and generally larger than life. The group that usually are fascinated by these dinosaurs the most are our children. It’s heartwarming when we see them light up like a light bulb when talking about a T-rex, or a Triceratops. This timeframe of our child’s life is a great window of opportunity to not only help them explore this attraction but to develop in them some long-lasting life skills. Dinomaniacs dinosaur games can be an effective bridge for mixing learning and enjoyment. Here are some important reasons why dinosaur games are great for learning:
They use interest to promote learning
Growing up in the world our children’s senses are flooded with plenty of things to stimulate them and peak their attention. The things that they pay the most attention to in their life will become their strongest interests. Many scientific studies have concluded that children learn more efficiently and effectively when their parents engage them with the things that interest them. We all want our beloved children to be interested and engaged with everything beneficial so we should make it a goal to invest the most time teaching them through their biggest influences.
Is your child interested in dinosaur toys or games right now? Perfect! Dinomaniacs has a digging egg game and dino race track game that your child will have a wide range of fun and learning with many activities! The digging egg game allows them to become a paleontologist and our Dino race track game lets them build their dino jungle outpost. It can be early exposure to science
Having visions of your child being a baby Einstein? I think we all have those dreams that our child will be a genius and do something great like solve world hunger! Every child has their strengths and weaknesses, so maybe that’s not in every kid’s future, but giving your child early exposure to science is a wise way to help them develop a hunger for learning. Science at its essence encourages people to explore their curiosity, inquire about the why, and use their brain to learn and solve problems. While every child will not be a super scientist, Dinomaniacs dinosaur toys for kids will help cultivate curiosity, exploration, inquiry, and problem solving, which science encourages. Included in each dino egg game are 12 informational cards, one for each dinosaur species to combine learning and fun.
Disarms their resistance to learning
At around 2 years of age, kids hit the stage that is infamously called…Terrible Twos! If you are familiar with this stage, you know that one of its familiar events is how a child learns to say no, and then repeat the process possibly thousands of times over time. This stage of life is helping them to become their own person. Still seeing the world as their playground, children in this stage still love to learn at this stage however they want to learn on their terms and are resistant to the learning parents want to give them.
Games and toys are excellent to disarm their resistance to learning, mainly because they don't feel forced to learn. All Dinomaniacs dinosaur toys for kids are STEM toys, which mean they are designed to mix play with learning.
Dinosaur games are great and can forge a path for our children to learn by piquing interest, exposing them to science early, and disarm their resistance learning. Are you ready to go dino? | 3,531 | 1,666 | 7,388.394958 |
warc | 202143 | Spacial Configuration Spacial Configuration Form/Shape of Room (A.f/SR)
From the supporting literature (linked above), irregular configurations considered as shapes and forms which all their sides and angles are not equal, and that affects the amount of noise/sound in the classroom. This inequality can take place in ceilings, walls, and floors.
Recommendations
1. Ensure that standards and regulations are enforced to optimize the performance of building envelope.
Glass and Window System (GWS) Dimension (GWS.D)
From the supporting literature (linked above), the total coverage of windows relative to the total wall area of the classroom influence the acoustic comfort of occupants. Having window sizes and dimensions that are not appropriate for the classroom affects indoor acoustic and students health.
Natural Light (NL)
From the supporting literature (linked above, daylight improves students behavior, achievement, and performance. Maximizing the use of natural light reduces heat gain, and increases savings by reducing energy demand, operation, and maintenance cost. Natural light guarantees improved health, productivity, safety, reduces stress and energy cost. Daylight also makes buildings sustainable and enhance their aesthetic view.
Recommendations
1. Promote the design of classrooms and buildings that maximize natural lighting.
2. The design of classrooms and choice of lighting system should be centered on the occupants, to reflect their psychological and physiological well-being.
3. Consider the age, height, and weight of students in determining the amount of light and color that is appropriate for them.
References
1. Barrett, P. et al. (2013) A holistic, multi-level analysis identifying the impact of classroom design on pupils’ learning. Building and Environment, 59, 678-689.2. Barrett, P. et al. (2015) The impact of classroom design on pupils’ learning: Final results of a holistic, multi-level analysis. Building and Environment, 89, 118-133.
3. Blackmore, J. et al. (2011) Research into the connection between built learning spaces and student outcomes Literature review. Department of Education and Early Childhood Development, State of Victoria.
4. Brown, Z.B. (2009). Occupant Comfort and Engagement in Green Buildings: Examining the Effects of Knowledge, Feedback and Workplace Culture. The University of British Columbia, Vancouver, BC.
5. Duyar, I. (2010). Relationship Between School Facility Conditions and the Delivery of Instruction: Evidence From a National Survey of School Principals. Facilities Management, 8(1), 8-25.
6. Earthman, G.I. (2002) School Facility Conditions and Student Academic Achievement. UCLA’s Institute for Democracy, Education, & Access Williams Watch Series: Investigating the Claims of Williams v. State of California (University of California, Los Angeles).
7. Earthman, G.I. (2004). Prioritization of 31 Criteria for School Building Adequacy. American Civil Liberties Union Foundation of Maryland. Retrieved in 2016 from http://www.schoolfunding.info/policy/facilities/ACLUfacilities_report1-04.pdf, Baltimore, MD.
8. Frankfurt Short Bruza (FSB). (2017). Oklahoma Healthy School Best Practices. University of Oklahoma, Norman, Ok.
9. Fukuchi, T., & Ueno, K. (2004) Guidelines on acoustic treatments for school buildings proposed by the Architectural Institute of Japan. Paper presented at the ICA- international conference on acoustic, Kyoto, Japan. Guideline retrieved from https://www.researchgate.net/profile/Kanako_Ueno/publication/268345588 Guidelines on acoustic treatments for school buildings proposed by the Architectural Institute of Japan/links/5508d0f30cf27e990e0cf6c8.pdf
10. McGuffey, Carroll W. (1982). “Facilities,” Chapter 10, Herbert Walberg (ed.) “Improving educational standards and productivity” Berkley: McCutchan Publishing Corp.
11. Oral, G.K., Yene, A.K. Bayazit, N.T. (2004) Building envelope design with the objective to ensure thermal, visual and acoustic comfort conditions. Building and Environment, 39(3), 281–287.
12. Uline, C., Tschannen‐Moran, M. (2008) The walls speak: the interplay of quality facilities, school climate, and student achievement. Educational Administration, 46(1), 55-73. | 4,267 | 2,098 | 8,536.033842 |
warc | 202143 | How to Start Evangelizing
Perhaps the biggest problem presented to us as Christians is that we are called to “make disciples of all nations”. In fact, we are quite explicitly told this, that the point of being a Christian is not merely our own salvation, but that of the people God has given us.
Throughout scripture, both explicitly and implicitly, we are told that our highest vocation is to love God and Neighbor. Real, effective evangelization seems to be one of the greatest ways we can do both. How better to love our neighbors than to show them the way to divine life? Not as teachers, necessarily, but as a beggar showing another where to get food. And how better to love God than to give him what he would (and did) die to possess: the souls of those he loves. Christ died that the sinner might become the Father’s own, and He invites us to participate in that mission.
Of course, none of this is likely new to you, reader. If you are reading this, the odds are good that you are already quite convicted of the need to share the gospel, and are trying to do so. My goal here, then, is to propose a problem that limits us.
I think we are bad at seeing.
More specifically, I think we do not see as Christ sees.
My friends, our first job, the first thing we have to learn as evangelists, is to see others as Christ sees them. And that’s a cliche, so I want to explain what that really means.
That doesn’t just mean tolerating and continuing to pursue people even though they’re frustrating, though it does mean that. That isn’t something we have to learn. That’s not a change of the heart, that’s just doing our jobs.
And it’s not merely internalizing the C.S. Lewis line about how we “never interact with a mere mortal”, because that’s just a fact. Facts alone don’t change our hearts.
No, when we’re told about Jesus looking at a young man who won’t give up his attachments in Mark chapter ten we are told that “he looked at him, and he loved him.” The love and the look are simultaneous with the young man’s rejection.
In John chapter one we’re told that he “looked at Simon” and tells him who he really is. He is Peter, foundation of this Church. Christ knows that Peter will fail him. Heck, he already has, but Christ sees Peter and sees the reason for his coming. The Bridegroom sees the bride.
My friends, to see someone as Christ sees them is to see as Adam saw Eve saying “Finally! Flesh of my Flesh and Bone of my Bone!” We would know that “This is why [we] came into the world”, to love the people we had been given to love.
But we, myself included, are so very very bad at this.
When we see a sinner, (outside of the mirror) the best among us may offer them one or two chances to stop, but we are not willing to hurt for them. We aren’t even willing to go without the dopamine hit we would get for a Social Media post indirectly or directly castigating and mocking them for their sin.
We will never witness to Christ if we fail to witness to his love, and we will never witness to his love if we are caught up in winning, or congratulating ourselves for our right belief. We (myself extremely included)
have to repent of our pride and our hatred which we let blind us. If we don’t view each sinner, each person we could get away with mocking or shaming, as someone Christ loves enough that he would die for them, we will never evangelize.
Of course this doesn’t mean excusing sin, but it does mean rejecting the prideful impulse to evaluate someone entirely on the basis of their sins, even if they celebrate them. We who have received love and mercy have no right whatsoever to withhold it, and as long as we do so, we will never evangelize.
So, to start evangelizing, we need to repent, but the good news is that God is endlessly merciful, even to us who know better than to deny Him and our neighbor the love we owe them.
Andy Brandt is a Staff Editor, Producer, and General Ne’er-do-well at Konza Catholic. You can find his writing on Catholicism, Justice, and Politics here . | 4,168 | 1,997 | 8,344.348523 |
warc | 202143 | ECMO offers sickest COVID patients a chance to survive, but a slimmer one than previously thought
New findings show importance of carefully selecting patients for a critical care treatment requiring intense staffing, specialized equipment and advanced expertise.
The life-support system called ECMO can rescue COVID-19 patients from the brink of death, but not at the rates seen early in the pandemic, a new international study finds.
Where once about 60% of such patients survived at least 90 days in spring 2020, by the end of the year just under half of COVID patients on ECMO survived that long.
The decreased survival over time might be due to a combination of factors, including which critically ill patients clinicians chose to place on ECMO as the pandemic went on, and the treatments the patients had received before they started on ECMO.
The new findings show how important it is for hospitals that offer ECMO to choose carefully which patients get access to this labor-intensive level of care, the authors say.
Hospitals should also make policies that can guide such choices when ECMO circuits are in high demand because of a pandemic surge, they advise.
The new findings are published in
Lancet by an international team co-led by ECMO experts from the University of Michigan, Singapore and Columbia University. The paper uses data from more than 4,800 patients over age 16 who were treated with ECMO for advanced COVID-19 in 41 countries during 2020.
The data for the study were contributed by ECMO centers to a registry run by ELSO, an international organization devoted to ECMO and other forms of advanced life support.
A last-chance option
ECMO, short for extracorporeal membrane oxygenation, has been used for decades in select hospitals to treat critically ill children and adults. It takes over for both the heart and lungs temporarily, circulating the blood outside the body under constant supervision of trained providers.
At the start of the pandemic, some experts had strong reservations about placing COVID-19 patients on ECMO, for fear of harming their lungs. As more centers began to try it, the survival rate mirrored that of ECMO’s use in other forms of acute lung failure, as the team behind the new paper reported a year ago.
But all the centers in that first study had begun offering ECMO before May of 2020, and most were highly experienced with providing ECMO in general, says Ryan Barbaro, M.D., M.S., co-first author of the new paper, associate professor at the U-M Medical School and intensive care physician at Michigan Medicine, the University of Michigan’s academic medical center.
The new study breaks the patients into three groups: those treated before May 1, 2020, those treated in these “early adopter” hospitals after May 1, and those treated with ECMO in other hospitals from May 1 through the end of 2020. May 1 was chosen because the evidence for how best to treat critically ill COVID-19 patients had evolved considerably by then.
“What we noticed right away is that the patients treated later in the pandemic were staying on ECMO longer, going from an average of 14 days to 20 days. They were dying more often, and these deaths were different,” said Barbaro. “This shows that we need to be thoughtful about who we’re putting on ECMO and when we’re making the decision to take patients off who aren’t getting better. Across the U.S. right now, we have places where ECMO is a scarce resource whereas in Michigan it’s not quite at that point, but we anticipate it might be.”
Within the “early adopter” centers, mortality rates increased from 37% in the months before May, to 52% after May. At the centers that didn’t start providing ECMO until at least May, 58% of the patients died within 90 days of being placed on an ECMO circuit.
Patients treated with ECMO later in the pandemic were more likely to have received medications such as remdesivir and dexamethasone, and to have received non-invasive ventilation before being intubated for total breathing support.
Decisions and ethics during a pandemic surge
Having patients stay on ECMO for a longer time ties up many resources, including the machines and tubing that make up an ECMO circuit, and the specially trained nurses, respiratory therapists and other staff it takes to keep a circuit operating safely.
When a hospital has a large number of COVID-19 patients and others in intensive care, the team’s ability to provide the same level of care that they did before the surge can suffer, and mortality might increase.
If many hospitals in a region or collection of states are coping with a large number of critically ill COVID-19 patients, it can be hard to find an ECMO-capable hospital to transfer patients to. Sending more ECMO circuits – the pumps, tubes and controllers used in the treatment – to these hospitals is not sufficient; specially trained teams, adequate blood supply and other factors are all needed to support each ECMO patient.
So, the authors say, it’s important for ECMO centers to carefully consider which risk factors and personal characteristics might make a patient more or less likely to survive if placed on ECMO, especially if they might need to be on for a while. ELSO offers resources and guidelines can help with patient assessment.
The research team used methods developed by U-M School of Public Health statistician Philip Boonstra to adjust the data to make apples-to-apples comparisons. This allowed them to ensure, for instance, that the survival percentages were not affected by the fact that so many more patients were transferred out of their ECMO hospital later in the pandemic compared with at the start.
In addition to working on the ELSO COVID-19 registry, Barbaro is leading a clinical observational study called ASCEND that is tracking ECMO outcomes in children and adolescents at nearly 100 hospitals around the world. As the Delta variant of the novel coronavirus spreads rapidly, the research team has already noticed that the majority of pediatric patients being placed on ECMO at this time are needing it because of COVID-19.
“In these moments of crisis, our ability to meet demand presents ethical challenges, and COVID has drawn out the weaknesses in our system, as well as showing how those with resources and relatives who can advocate on their behalf are more able to find out about ECMO and seek the opportunity for their loved one to be treated,” Barbaro said. “Meanwhile, hospitals in non-surge areas need to reflect on what policies and procedures they’ll use if they experience another surge, to foster ethical allocation when resources are constrained.”
Paper cited: "Extracorporeal membrane oxygenation for COVID-19: evolving outcomes from the international Extracorporeal Life Support Organization Registry," Lancet. DOI: 10.1016/S0140-6736(21)01960-7 | 6,967 | 3,155 | 15,053.57813 |
warc | 202143 | This past weekend I had the chance to speak on a panel on leadership with other super accomplished Latinas (including an elected official!). It’s always a great opportunity to glean tips and knowledge from others both in the audience and fellow panelists. Because we were discussing leadership, one of the big themes was having the confidence to go for it-to go for the leadership roles and have faith in your ability. I totally agree. You have to be aware of your abilities and have the confidence to know your strengths and talents and to push yourself to the next level because you know you got it (or have the skills…
I’m going to reveal a big secret—a lot of law grads and new attorneys don’t exactly know what kind of lawyer they want to be. Seriously! Maybe you go to law school with the exact idea of what you want to do and stay the course—that’s great! But maybe you’re unsure because all you know is you want to “do good” or make money but not sure how that looks. Or maybe you have an idea of what you want to do but one day you are in torts class and suddenly realize you have a passion for personal injury (which I’m adamant is how personal injury attorneys are born).…
We’ve discussed networking before of the many pitfalls that can come with it but lately I’ve seen some takes on networking that doesn’t seem to capture the purpose of what this type of relationship building really involves. I understand why—as a new student or professional, you’re often bombarded with the cry to “network!” And it promotes this idea that you go to these events to meet people to see how they can help you. It feels transactional and disingenuous and icky. And yes, part of networking is to meet people with connections, especially if you’re job seeking, but if you’re only going to these events when you need something, then…
First, if you’re new a attorney—whether you just received your law license or are awaiting bar exam results, CONGRATS! That is such an exciting time and not to be dramatic but this marks the beginning of your career as a lawyer and how you’ll participate with your local legal community—the possibilities are endless! But it may not feel that way as you get used to process of being a lawyer; the day to day stuff that can be a little tedious, plus possibly adjusting to a new work/office culture as well. Oh! And add loan payments but also substantial paychecks that you also have to learn how to manage—especially for…
First, if you haven’t had a chance to do a deep dive in the latest legal profile by the ABA here it is. It is full of great gems and covers various sectors but as usual focuses heavy on big law. Ultimately, what the profile reveals is that it is hard out here for a Latina attorney. Latinx have the highest rates of attrition, attorneys of color, in general, are less likely to be promoted to equity partner than white attorneys and more likely to leave the firm. Women also left during COVID to take care of households and that will have long-lasting implications that we are yet to see.…
I can’t even believe that Latinas Uprising is turning seven this week! When I hit publish in summer 2014, I had no idea—I could not have imagined—the type of community this would form. All I knew was that I wanted to find other Lawtinas like me and offer whatever support I could. From that grew a community of fierce, engaged, and driven people who work to make this profession better. I’m alway so grateful for everyone who reads this space and for the support and encouragement provided. Seven years went by in a flash! So I wanted to share some of our top posts, those that created dialogue and motivated…
So, two years ago, which already feels like a lifetime, I started my job in policy (within a local govt branch). To say it’s been eventful is an understatement. Not only was this my first job in policy, it was only second job post-law school—after working for almost a decade. I had been at my old job in legal aid since I graduated. I grew up in legal aid and will forever feel like a legal aid attorney. But it was time to go and me being me, I picked something so different and challenging that the first few months, I honestly wasn’t sure if I could succeed. Then came…
Updated June 2021: I wrote this originally when I had been practicing just four years. Since then I’ve experienced even more forms of racial and gendered harassment. Things like: Client’s not wanting me to represent them because I was not white Inappropriate/sexualized comments by outside parties More microaggressions than I can even count… But even still my answer on how to respond to disrespectful clients has only changed slightly. That’s because while the landscape has changed—I notice that for new attorneys the fear of speaking up isn’t as prevalent as it used to be—I don’t think we’ve made as much progress in the profession that the risk of backlash isn’t…
We’ve discussed goal setting before (a lot!) but today I wanted to share a little more on why goal-setting is so important, especially when you’re new. Because when you’re a new attorney and new to the professional world, it’s easy to think that your firm or boss will always keep your career growth in mind. And some might! Some firms are really good at performance evaluation and career development, but your career is too important to leave in the hands of others. It’s important to set long-term and short term goals for yourself so that regardless of what your firm does or doesn’t do, you are developing as an attorney…
A few days ago I posted about the quandary I often feel in discussing professional norms and how to abide by them while understanding that those norms are rooted in classism, sexism, and racism. As always, my goal with teaching “how tos” is not to push for assimilation but rather to uncover these unspoken rules so people can decide which, if any, to follow. And how one abides by those norms is wholly dependent on your own career goals, current needs, and other obligations. Ok, but say you quickly learn and adapt to these standards, what does that mean? It means that while you’ve figured out the way to advance… | 6,452 | 3,091 | 12,807.981883 |
warc | 202143 | Regardless of where you live, you are bound to experience a bout of rain at some point of the year. The rainy season is a hoot. Everything is clean and glistening. The air is fresh and breezy. Who doesn’t love the rain? Of course, too much rain can be a little bothersome especially when it comes to winter clothing. The rainy season calls for special attire. Rain boots and raincoats are a must-have for everyone. Most garments are generally designed to resist moisture if they are machine washable.
Leather, however, is a little different and the most commonly used leather product is a leather jacket.
There are many benefits of a leather jacket. It is strong, functional and extremely durable. However, leather is still quite susceptible to damage; particularly the kind resulting from moisture. A small amount of moisture is not a problem for the tough and mighty leather, but when exposed to a prolonged period, moisture can cause significant leather damage. It settles into the pores of the leather and results in the formation of mildew and mold; both of which are extremely damaging and hard to repair.
So the question remains: can one wear a leather jacket in the rainy season? Of course, you can, but you need to be a little careful. First, let’s narrow down some of the advantages of wearing a leather jacket in the rain.
Leather jackets are waterproof. The outer leather layer allows the water to slide off of it thereby exhibiting a fantastic water-repelling quality. The rain, when it hits the leather jacket, forms little beads and rolls off leading the jacket and the wearer rain-proof. Hooded mens leather jackets are the best for the rainy season serving a dual function of a jacket and a raincoat. Who said you cannot be fashionable in the rain?
Leather jackets seem heavy, but they actually are not. By design, leather jackets are relatively lightweight and wearable. Perfect for layering, you can wear your jacket over other layers to keep you protected if the rain and the accompanying wind gets too harsh. In the rain, it is already quite difficult to manage things according to the situation. A heavy outer layer only makes it worse. A lightweight leather jacket should be the one for the time of the year.
While some may think waterproofing and breathing ability do not go hand in hand but with a leather jacket, they do. In addition to being waterproof, leather jackets come with an inner lining that is usually made with different materials. All the materials used are designed to be breathable so that moisture cannot build up in them. If by any chance moisture does find its way into the jacket, it is nothing that air drying cannot fix. Additionally, this feature allows heat and sweat to evaporate from the jacket; a great feature to manage internal heat regulation. Stay comfortable and dry in a leather jacket this rainy season.
A leather jacket, despite being formal and fancy, is easy to manage and thus can be stowed away neatly. You can easily bundle them up and stow them making them great for traveling as well. Synthetic leather jackets that come with a thinner lining are ideal for this purpose. Many advise against folding up a leather jacket thinking it will get ruined, but a leather jacket is malleable in that aspect. If you fold it neatly, there is no fear of any wrinkling or lines. Hang your jacket for a while, and the folds get erased on their own.
The most important benefit of a leather jacket is its edgy aura. Leather jackets exude a sexy and effortless vibe which is perfect for layering. A custom leather jacket just completes every outfit. Wear your jacket over a casual outfit or something a little bit more special; f there is one thing that is guaranteed is a killer fashion statement. They are surely chicer than your average raincoat after all.
Apply a water-resistant leather lotion on your jacket. There is a wide assortment of lotions to choose from each with their own unique set of properties. All of them, however, do a fantastic job of protecting leather from the destructive effects of moisture. This external protective barrier is a savior for your jacket in the rainy season.
Dry your leather jacket from time to time if it is regularly exposed to rain. If your jacket remains saturated with moisture, the jacket will get damage much faster, so the risk is automatically increased. After your jacket has been soaking in the rain, once you reach your destination, wipe it dry. This keeps the jacket protected even further. Make sure to not fold it up immediately. Leave the jacket out to air dry as well. There are many different types of leather. A synthetic or faux leather jacket is the best when it comes to offering protection from the rain. It is designed to withstand the effects of moisture much better than real leather. So if you are looking for a jacket for the rainy season, it is best to get your hands on a synthetic leather jacket. They are just as good as pure leather jackets and much more affordable. Who wouldn’t enjoy that?
Leather jackets are a true statement and versatile garment that can be worn with anything, to any occasion, and in any weather. Their effortlessly simple aura is hard to compete with so rest assured, a leather jacket is an investment. One of the standout benefits of a leather jacket is its longevity. A leather jacket, if properly taken care of, only gets better with time.
If you are on the lookout for a good leather jacket that promises excellent quality at an incredibly good price, Leather Skin Shop is the place for you. Home to some of the most exquisite designs on the market, at Leather Skin Shop, there is something for everyone. Whether you love to keep it simple or go all out, Leather Skin Shop is the place where you can have it all. This rainy season, flaunt your leather jacket in style.
Winter closet does not mean you compromise your inner fashion geeks, alright? Feel all covered up yet still outshine others with your sexy appeal, that’s the main aim of our winter shopping guide. Don’t forget you can always get a custom leather jacket made by LSS for you specially if you have a unique style.
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Choosing the perfect outfit is always a priority for people, but don't forget that choosing the perfect pair of shoes for the occasion is just as important. Wearing the right shoes can elevate your outfit and can make you stand out among others whereas wearing wrong shoes can blemish your overall look.
This guide is a must read to help you choose perfect shoes for every occasion and how to select custom shoes for men.
Can't wait to style your outfits so that all eyes will be drawn to you? We certainly can't! Don't forget to enjoy and celebrate the Thanksgiving holiday with your close friends and family before the snow falls and the Christmas bells ring.
Thanksgiving is all about gathering together, spreading love, and celebrating life with a positive mind and attitude.
In this blog we'll help you suggest a few style inspirations that will help you develop a statement outfit this holiday season. | 7,131 | 3,136 | 16,110.693559 |
warc | 202143 | Height of irresponsibility for Muhyiddin not to convene Parliament in August when the country is heading towards 1.5 million Covid-19 cases and over 15,000 death on 64th National Day and some two million Covid-19 cases and 20,000 deaths on 58th Malaysia Day
There has been no let-up in the surge of Covid-19 cases in Malaysia as yesterday registered a new daily record of 20,899 Covid-19 cases and 160 new Covid-19 deaths.
Malaysia is facing a double crisis – a constitutional crisis which has reached a new peak with the resignation of two UMNO Ministers and the Covid-19 pandemic continuing its worst ravages.
Malaysia should not reach a position where some 200 people are dying a day and some 20,000 people are infected with Covid-19.
Two weeks ago, the Health director-general Noor Hisham Abdullah projected that that Malaysia will reach the peak of Covid-19 transmissions in mid-September with 24,000 cases a day, but it appears that he was being too conservative, as the 24,000 cases a day may be reached as early as mid-August instead of mid-September.
What should be a matter of real nation concern is the height of irresponsibility by the Prime Minister Muhyiddin Yassin in not convening Parliament in August when the country is heading towards 1.5 million Covid-19 cases and over 15,000 Covid-19 deaths on 64th National Day on August 31 and some two million Covid-19 cases and some 20,000 deaths on the 58th Malaysia Day on Sept. 16, 2021.
What is the Muhyiddin government doing to avert these calamitous numbers on our 64th National Day or 58th Malaysia Day?
Community activist Dr. Mohamad Rafick Khan has dissected Noor Hisham’s claim about Covid-19 in Parliament, used to justify the shut-down of the Parliament special meeting on July 29, truncating two sittings of the Dewan Rakyat and three sittings of the Dewan Negara.
Hisham Noor said that based on the case screening conducted by the Health Ministry on the Parliament special sitting, a total of 85 cases have been found.
However 56 out of 85 positive people were tested from the pre-Parliamentary session. This means that the 56 did not get infected in Parliament but from elsewhere. That leaves 29 people infected positives. Another were from close contacts i.e. they were not from Parliament. That leaves 25 people infected during the Parliamentary sitting.
Who are these 25 people? So far no public information has been released on who is infected. None of the MPs made a public statement that they were infected. What is clear is that no one had been infected because of the parliamentary debates.
There is only one conclusion that the Covid-19 risk assessment of the Parliament special meeting was presented negatively to justify the Parliament shut-down.
This should not be the act of the non-partisan public servant as it undermines his credibility.
The events of UMNO Ministers and MPs withdrawing their support from Muhyiddin after the meeting of the Prime Minister and the Yang di Pertuan Agong have created a new situation demanding the immediate meeting of Parliament in August to determine whether Muhyiddin still commands the confidence of the majority of Parliament.
Muhyiddin should not delay any further until September and should convene a special meeting of Parliament to determine his future as Prime Minister of Malaysia. | 3,339 | 1,461 | 7,571.599589 |
warc | 202143 | 2 edition of
Health status and utilization found in the catalog.
Health status and utilization
Judith Kasper
Edition Notes
Statement by Judith D. Kasper Contributions United States. Health Care Financing Administration The Physical Object Pagination 17 p. ; Number of Pages 17 ID Numbers Open Library OL14911026M
Gender, socio-economic status and utilization of health care. Care utilization by dementia patients living at home. Utilization of physiotherapy and self-help by patients with rheumatic diseases. Social determinants of utilization of psychotherapy, prevention, and integrated care in Germany. This book summarizes findings on trauma and PSTD in relation to three domains of outcomes: health status and disease, somatization, and utilization and :
Population Health • Principles of Population Health Management: • Describes the demographics, needs, and health status of the enrolled population • Appropriately forecasts and manages demand and capacity • Proactively delivers preventive services • Manages medical and disease conditions. This section presents data on the health insurance status and utilization of health services within the child population. Data are summarized by source of payment, type of care, and place of service delivery where appropriate and feasible. Health insurance is critical for ensuring the health and well-being of children in the United States.
Table of contents • Pages 2 - 8 Reviewing your utilization review program Learn how to evaluate your admissions review program and recommended workflow processes • Pages 9 - 12 CMS regulations and guidance Navigate short inpatient stays, audit risks, “gray” cases for second-level review. The health status of the elderly in the poor areas is a matter of concern. This study aims to explore the status of the elderly in terms of their health status, health service needs, and utilization among rural residents of a remote and poor village in a mountainous area in Jinzhai, : Chaoqun Hu, Wenya Yu, Yipeng Lv, Haiping Chen, Qiangyu Deng, Lulu Zhang.
Ancestors
Log of the federal-aid interstate system comprising the Nevada primary state highway system, 1985
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Richard Long.
Agfacolor user processing
1040 Preparation
Warhol, Beuys, Polke.
Beverly Pepper: Markers 1980-2002
Collins dictionary of personal computing
opinion of Taiwans banking complaint experiences
Health status and health care utilization measures are central indicators of the performance of the health care system. Major changes underway in the organization and financing of medical care Cited by: Health status and utilization: Differences by Medicaid coverage and income by Judith D.
Kasper By several measures of health slatus, the Medicaid population is in worse health than are persons without Medicaid. In addition, poor persons without Medicaid coverage. Older adults use far more health care services than do younger groups.
Although older adults vary greatly in terms of health status, the majority of them have at least one chronic condition that requires care. Older adults also vary in their demographic characteristics, which leads to differences in their demand for and utilization of health services.
Health status and the need for health-care services to improve or maintain health are major determinants of health-care utilization. The World Health Organization states that health is determined by a person’s individual characteristics and behaviors, physical environment, and socioeconomic environment (WHO, ).
People’s individual. Book Review: The Impact of Cost-Sharing on Appropriate Utilization and Health Status: A Review of the Literature on Seniors Thomas Rice and Karen Y. Matsuoka Medical Care Research and Review 4, Cited by: Health Care Health status and utilization book is the quantification or description of the use of services by persons for the purpose of preventing and curing health problems, promoting maintenance of health and well-being, or obtaining information about one’s health status and prognosis.
Background. Self-reported health status and healthcare services utilization of population are indispensable indicators to assess the performance of health system in the context of limited health administration data [1, 2], particularly in developing countries [2, 3].They contribute evidences not only to estimate the future demand of healthcare [], but also to evaluate the health disparities Cited by: Download Health Status and Medical Services Utilization: [PDF.
Get this from a library. Health status and utilization: differences by Medicaid coverage and income. [Judith Kasper; United States. Health Care Financing Administration.].
Jennifer H. Madans, in International Encyclopedia of Public Health (Second Edition), Abstract. Information on health status, risk factors, health insurance, and health-care utilization is used to plan, conduct, and evaluate public health programs, to inform policies, regulations, and legislation, and to conduct research to better understand the determinants and consequences of health and.
Toolkit contains 5 handbooks and 5 pocket cards. Make sense of medical necessity, condition codes, and patient notices while reviewing cases.
The Patient Status Training Toolkit for Utilization Review is a quick-reference handbook and pocket card that will serve as an everyday guide to utilization review (UR). The handbook is a practical guide that UR committee members can keep at their desk 1/5(1).
Effects of health literacy on health status and health service utilization amongst the elderly. Soc Sci Med. ;66(8)– 30 Sudore RL, Mehta KM, Simonsick EM, Harris TB, Newman AB, Satterfield S, et al. Limited literacy in older people and disparities in health and healthcare access.
J Am Geriatr Soc. ;54(5)– Health status, work productivity loss, activity impairment, health care resource utilization, and annual costs associated with MS (n=85) were compared with controls without MS (n=,).
Get this from a library. Health status, health insurance and health services utilization, [Shailesh Bhandari; U.S. Census Bureau.]. Perceived health status by socio-economic status. Infant health: low birthweight. Communicable diseases. Cancer.
Injuries. Absence from work due to illness. Non-Medical Determinants of Health. Non-Medical Determinants of Health - Key Indicators. Tobacco consumption. Alcohol consumption. Food supply and consumption. In each issue, Health Affairs offers an annual check on a segment of the health sphere: health status and health care utilization in Spring; health care innovation in Summer; national health spendi Cited by: Book Review: The Impact of Cost-Sharing on Appropriate Utilization and Health Status: A Review of the Literature on Seniors December Medical Care Research and Review 61(4) The national health spending for Americans has increased in recent years and is projected to continue on a rapid growth trajectory.
1 This phenomenon is subject to the interplay of many forces, both demographic and economic. 2 People are living longer, have declining health status for more years than in the past, and are consuming more medical services. 3 Regardless of demographic. Read - Profile of Metis Health Status and Healthcare Utilization in Manitoba: A Population-Based Study: Martens, Patricia, Bartlett, Judith, Burland, Elaine - desLibris.
With regards to equity, the objective for health care systems is “equal access for equal needs”. We examined associations of predisposing, enabling and need factors with health facility utilization in areas with high HIV prevalence and few people being aware of their HIV status.
The data is from a population-based survey among adults aged 15years or older conducted in Cited by:. Health-Care Utilization as a Proxy in Disability Determination.
Washington, DC: The National Academies Press. doi: / Health status and need for health care to improve or maintain health are major determinants of health-care utilization. Ideally, need should be the major determinant of healthcare utilization, but other factors.and measure equity in health status and health care utilization using the equity index.
The study also introduces a methodology to explain equity in terms of between- and within-group equity. The proposed methodology is applied to the Philippines using Demographic and Health Surveys and Annual Poverty Indicator by: 7.Gender and utilization of health care.
Care utilization by dementia patients living at home. Social determinants of utilization of psychotherapy in Germany.
A volume certain to spark discussion among researchers across the community, the findings and methods in Health Care Utilization in Germany will be analyzed by health psychologists, public. | 8,824 | 3,858 | 19,905.461897 |
warc | 202143 | Posts tagged ‘XLVI’
Eli Manning and Tom Brady are arguably the smartest pair of quarterbacks to face each other in a Super Bowl. That’s not just hyperbole; there’s data to support it. Manning scored a 39 on the Wonderlic test, and Brady scored a 33, giving them an average score of 36. That’s the highest average ever for the starting quarterbacks in a Super Bowl.
The two starting quarterbacks for Super Bowl XLVII, Colin Kaepernick and Joe Flacco, are no intellectual slouches, either. Flacco scored a respectable 27 on the Wonderlic, and Kaepernick rocked the test with a 37, placing him
two standard deviations above the norm. That puts him in the 97th percentile. If he wins the Super Bowl this Sunday, he’ll be the second-smartest quarterback to do so.
Last week, I asked readers to supply me with data for a research project. The Wonderlic test is used by the National Football League to measure the problem-solving abilities of prospective players. The SAT (and the ACT) have long been used as college entrance exams, and both claim to predict college success. My hypothesis is that the Wonderlic — a 12-minute, 50-question test — would be equally good at predicting college success.
The following presents the (I) results, (II) limitations of the research, and (III) some notes about the methodology. (Sorry, I don’t mean to be pretentious or to imply false erudition by using Roman numerals. I just know that some folks are interested in (I) but could give a rat’s butt about (II) or (III), so I thought dividing this post into sections might be helpful. Hopefully by using the phrase “rat’s butt,” I’ve removed all sense of pretense.)
I. Results
Neither the SAT nor the Wonderlic are good at predicting college success, but to my surprise, the SAT is better than the Wonderlic.
The following correlation coefficients resulted when three pair-wise correlations were performed:
Wonderlic and GPA: r= 0.0086 SAT and GPA: r= 0.0506 Wonderlic and SAT: r= 0.2897
When comparing the Wonderlic and college GPA (
n = 46), the correlation coefficient was r = 0.0086, meaning that roughly 9% of the variance of college GPAs can be explained by Wonderlic scores.
When comparing the SAT and college GPA (
n = 41), the correlation coefficient was r = 0.0506, meaning that roughly 22% of the variance of college GPAs can be explained by SAT scores.
When comparing the Wonderlic and SAT (
n = 44), the correlation coefficient was r = 0.2897, meaning that roughly 54% of the variance of college GPAs can be explained by Wonderlic scores.
Though not quite as strongly, these results corroborate my previous findings that neither the SAT nor the Wonderlic is a very good predictor of college success, but both are pretty good predictors of scores on other standardized tests.
II. Limitations
A number of factors discredit the validity of this research, among them:
Voluntary Response Bias.The majority of respondents were above average in all categories. Additional data is needed from individuals who scored poorly on the SAT/ACT or Wonderlic or who had below-average college GPAs. Sample Size.It is difficult to draw conclusions from a sample of just 54 individuals. Timing.Those who responded often took the Wonderlic many years after taking the SAT. This is an issue with data from NFL prospects, too; they take the SAT prior to entering college, but they take the Wonderlic at least three years later. Certainly, those years of experience would influence the results. Consistency.College GPA is not transferrable. Without a doubt, earning a 3.1 GPA at Harvard University is more impressive than holding a 3.9 at the Univerity of the District of Columbia. Even within the same university, there can be discrepancies; it’s likely more difficult to hold a high GPA if your major is electrical engineering than, say, parks and recreation. Unfortunately, it’s one of the only means of comparing two students from different schools, apart from reputation of the issuing institution.
Consequently, this research should be taken in the spirit it was intended. It it not academic research. It was merely a tongue-in-cheek attempt to show that neither the SAT/ACT nor the Wonderlic test are terribly good at predicting college success.
That said, this analysis could serve as the impetus for an academic research project. By gathering Wonderlic scores from high school students at the same time that they take the SAT, and then tracking them to determine their success in college, the viability of the Wonderlic test as a college entrance exam could be determined. (It should be noted that the Wonderlic Personality Test (WPT) is used by the NFL when evaluating prospective players, but scores on the Wonderlic Basic Skills Test (WBST) are already accepted by some colleges.)
III. Notes About the Method
For consistent comparison, all college exam scores were converted to a scale based on the old SAT (out of 1600). ACT scores were converted using results of a concordance study conducted by the ACT and the College Board. Converting scores from the new SAT to the old SAT used the method described below.
Because the maximum score on the new SAT is 2400 and the maximum score on the old SAT was 1600, the following conversion formula might seem reasonable:
2/3 × new SAT = old SAT
However, there are two reasons that won’t work. First, in addition to covering the same math topics as the old SAT, the new SAT also covers Algebra II. Second, the writing section has proven to be the hardest part of the new test; the average score on the writing section is 493, since its inception in 2005; by comparison, the average scores for math and reading are 516 and 501, respectively, during the same time period.
Using scores from 2000-11, it seems that approximately 67.3% of a student’s score on the new SAT comes from the math and reading sections; the writing section only accounts for about 32.7% of the student’s total score. Second, the average score on the old SAT from 2000-05 was 1024, whereas the average combined score for the math and reading sections on the new SAT from 2005-11 was 1017, which means that the average score on the old SAT was about 0.7% higher than the average combined score on the math and reading sections of the new SAT.
Consequently, for any respondent who listed a new SAT score, I multiplied their score by 0.673 to find their score on just the math and reading sections, and then I multiplied by 1.007 to account for the higher average score on the old SAT. This is obviously an imperfect system. That said, one of the respondents told me that his combined math/reading score on the new SAT was 1390, and this formula yielded an old SAT estimate of 1410. Since the old SAT score should be slightly higher, it seems that the formula is reasonable. I therefore used this formula for all respondents who listed a new SAT score, of which there were only two.
No changes were made to the college GPAs, despite the inherent flaws described above.
Once the data was in comporable form, my good friend Excel was used to perform a linear regression and determine the correlation coefficient.
There were a lot of interesting mathematical things that happened tonight.
First things first: Big props to Valerie Strauss of The Answer Sheet, who asked, “Tom Brady vs. Eli Manning: Who’s Smarter?” and then was smart enough to link to one of my previous posts when trying to answer the question.
Math Incident #1
Within the first five minutes of coverage, it was announced that the NFC had won 14 consecutive coin tosses. Posted on the screen:
Odds: 1 in 16,384
I was a little bummed that it didn’t say, “Odds: 1 in 2
14.” But I can’t complain. It’s not every day that probability gets international publicity.
Math Incident #2
With just under 4:00 left in the game, Wes Welker dropped a pass from Tom Brady. During the replay, Cris Collinsworth said that it was a pass that Welker makes “100 times out of 100.” Um, Cris, in case you missed it… I don’t know how many passes just like this that Wes Welker has caught, but he missed this one, so we have at least one data point showing that, in fact, he doesn’t always catch this pass. If you want to revise your statement to “99 out of 100,” I could live with that.
Super Bowl Squares Online Contest
The results of the Super Bowl Squares Online Contest have been posted at http://mathjokes4mathyfolks.com/super-bowl-squares-results.html. But allow me to spoil some of your fun before you click that link:
There were no winners for the first quarter score (Patriots 0, Giants 9; winning square, 9‑0). There were no winners for the second quarter score (Patriots 10, Giants 9; winning square, 9‑0). There were no winners for the third quarter score (Patriots 17, Giants 15; winning square, 7‑5). There were twowinners in the fourth quarter (Patriots 17, Giants 21; winning square, 7‑1).
That means that Ben Morris and Tom Coffin were the only winners of the 31 participants, so they split the $155 pool of Monopoly money, each receiving $77.50.
Your math/football trivia for the day?
Super Bowl XLVI is the second to require each of the first four Roman numerals (I, V, X, L); the first was Super Bowl XLIV two years ago. [Thanks to Eric Langen for pointing out my previous error.] Personally, I’m looking forward to Super Bowl LXVI, when the first four Roman numerals will occur in decreasing order. A real treat will occur in 3532, when Super Bowl MDLXVI will be played, wherein all six of the Roman numerals will appear in decreasing order. While I’m fairly certain I won’t be around to see that one, I hold out hope that I am reincarnated as a star football player who earns that game’s MVP honors; though it’s far more likely that I will return as a football to be used by adolescents in a backyard game.
Buoyed by the success of the online version of my favorite game, I’ve decided to run another online contest. This one relates to Super Bowl XLVI, and you’re asked to predict the units digit of each team’s score at the end of each quarter when the Patriots and Giants square off on Sunday, February 5.
Probably the most common type of office betting pool is a square football pool, which is often referred to as just The Squares. The pool is played on a 10 × 10 grid, and contestants can buy squares within the grid for a certain amount of money.
After all 100 squares have been purchased, the numbers 0‑9 are randomly assigned to each row and column. The numbers for each row represent the units digit of the score for one team, and the numbers for each column represent the units digit of the score for the other team. The winners are the four people whose squares correspond to the units digit of the actual score of the game at the end of the 1st, 2nd, 3rd, and 4th quarters.
Feel free to use this Excel spreadsheet if you’d like to run your own version of this game. (Though be sure to check all applicable laws, to ensure that you’re not in violation of local or state gaming laws.)
The difference between the typical version of this game and the version I’m running here is that
you get to pick which pairs of numbers you want. Consequently, winning isn’t solely a matter of random luck. But there’s a catch — you can pick the most likely number pairs, but chances are other folks will pick those numbers, too, and the winnings are divided among everyone who picked that pair. So, should you pick 0‑0 and divide the pot with a thousand others; or should you pick the highly unlikely 5‑2 and have the winnings all to yourself? Please note that the game I’m running is for entertainment only. No money is required to play, and there will be no pay-out to the winners. If all goes well this year, perhaps next year there will be a real version that allows you to wager your hard-earned money in such a silly manner — assuming, of course, that I can find a way to skirt the myriad state gaming laws that would prevent me from running such a contest.
In case you’re wondering, “Why are you doing this?” remember that I’m the author of a math joke blog. Why do I do any of the things I do? For fun, mainly, and because I’m a certifed math geek. I like the math psychology of this game, and I’m just interested in the numbers that people will pick.
Here are the official rules:
Imagine that you have $5, and each square costs $1, so you can buy up to five squares. It’s your money, spend it how you like — if you want to choose the same pair of numbers for all five bets, go ahead, knock yourself out. And what the hell do I care? Enter as often as you like; if you’ve got nothing better to do with your time than repeatedly submit entries for this contest, well, that’s your problem. All money bet will be divided equally among the four quarters, so the total amount will be equal to $5 n, where nis the number of contestants. (Should a contestant enter fewer than five choices, the last entered choice will be repeated multiple times to get the total to five.) If you pick a winning square, you will share the winnings with everyone else who picked the same square. (For example, if 200 people play this game, there will $1,000 in the pot, so the winning amount for each quarter will be $250. If ten people choose 7-3 and it hits for one quarter, each person will receive $25.) Enter your five choices as two-digit numbers, where the tens digit represents the Patriots’ score and the units digit represents the Giants’ score. (For instance, if you want Patriots 7, Giants 3, enter 73; but if you want Patriots 0, Giants 7, enter 07.)
That’s it. Access the form via the link below:
My friends Andy and Casey Frushour have been keeping data about which pairs of numbers occur most often. Before making your picks, you might want to check out their analysis of data from six years of NFL games as well as from all 45 Super Bowls.
Bets will be accepted until 11:59 p.m. ET on Saturday, February 4, and an image showing the number of times each square was chosen will be posted at:
The complete results for this contest will be posted on Monday, February 6, at the URL below. (But note that this link will return a “404 Error – File not Found” message prior to February 6.)
Good luck! | 14,578 | 6,292 | 32,765.746345 |
warc | 202143 | No Dogs Available
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Genetic Age
Please note that genetic age is different from calendar age. We cannot (yet) estimate calendar age—how long since your dog was born—from DNA. To learn how vets estimate calendar age you can read How old is your dog? How veterinarians estimate dog age.
The genetic age that we report is an estimation of where your dog is in his or her healthspan. Dogs age at very different rates due to a number of genetic and environmental factors. Body size is a strong genetic influence: for example, a seven year old Great Dane is at the start of his golden years, but a seven year old Pomeranian is just learning what "slow down" means. Just within this example, you can see that the old "one doggie year = seven human years" adage isn’t going to work. And yet, knowing your dog’s age is important: it informs what your dog needs as far as food, frequency of veterinary checkups, and exercise. So how do you best determine how old your dog is?
Embark's genetic age feature calculates how old your dog would be if he or she were aging at an average human rate (using humans in the USA as the baseline). So going back to our Dane/Pom example, we'd estimate a seven year old Great Dane at about 80 years old (senior citizen), but a seven year old Pom would be about 42 (adult). Makes way more sense, right?
Calendar age Genetic age 1 year 17 human years 2 years 25 human years 3 years 31 human years 4 years 37 human years 5 years 43 human years 6 years 49 human years 7 years 55 human years 8 years 61 human years 9 years 67 human years 10 years 73 human years
All we need from you is a calendar age. It's okay if this is an estimation: it is just a starting point. We then factor in your dog's breed composition, information at certain genes that affect size, and their inbreeding coefficient to calculate genetic age. Like in humans, in dogs females tend to live longer than males (so an “80 year old” female dog = 80 year old woman). Exercise and diet also play a role in how long your dog will live. Nevertheless, genetic age is the primary risk factor for numerous diseases in dogs, including cancer, kidney disease, osteoarthritis, cataracts, cardiac disease and cognitive decline. It can help you and your vet know what you should feed your dog, what screenings to get, and other aspects of your dog’s care.
Wolfiness score How wolfy is my dog?
Most dogs have wolfiness scores of 1% or less. We find populations and breeds with higher scores of 2-4% occasionally, and unique dogs with scores of 5% or above more rarely.
What it means for my dog
Your dog’s Wolfiness Score is not a measure of recent dog-wolf hybridization and does not necessarily indicate that your dog has some recent wolf ancestors. (If your dog has recent wolf ancestors, you will see that in the breed mix report.) Instead, the Wolfiness Score is based on the number of ancient genetic variants your dog has in our unique Wolfiness marker panel. Wolfiness scores up to 10% are almost always due to ancient wolf genes that survived many generations, rather than any recent wolf ancestors. These ancient genes may be a few thousand years old, or may even date back to the original domestication event 15,000 years ago. They are bits of a wild past that survive in your dog!
The science
Your dog’s Wolfiness Score is based on hundreds of markers across the genome where dogs (or almost all of them) are the same, but wolves tend to be different. These markers are thought to be related to "domestication gene sweeps" where early dogs were selected for some trait. Scientists have known about “domestication gene sweeps” for years, but do not yet know why each sweep occurred. By finding rare dogs carrying an ancient variant at a certain marker, we can make associations with behavior, size, metabolism, and development that likely caused these unique signatures of “doggyness” in the genome.
Predicted Adult Weight How does weight matter?
For people with puppies, you probably want to know how big of a crate to buy or just how big to expect your dog to become. But genetic weight is also useful for people with fully grown dogs. Just like with people, overweight and obese dogs suffer reduced length and quality of life. They can develop chronic health conditions and suffer from limited mobility and other issues. While over half of American dogs are overweight or obese, fewer than 15% of their owners realize it. By comparing your dog’s weight to their genetic predicted weight you have one more piece of information about their ideal weight. With this and other pieces of information like weight history and body condition, you and your veterinarian may want to discuss your dog’s diet, exercise, and weight control plan to give your pup the longest, healthiest life possible.
How do we predict weight?
Our test is the only dog DNA test that provides true genetic size not based just on breed ancestry but based on over a dozen genes known to influence a dog’s weight. It uses the most advanced science to determine your dog’s expected weight based on their sex, the combination of these genes, and breed-specific modifiers.
How accurate is the predicted weight?
Unlike in people, healthy weight in dogs is controlled largely by only a few genes. Our algorithm explains over 85% of the variance in healthy adult weight. However, due to a few as-yet-undiscovered genes and genetic interactions that affect size, this algorithm sometimes misses. Occasionally it misses by a fairly large amount especially when a dog has a breed with an unknown size-influencing gene. If we have missed your dog’s weight, your dog may be a scientific discovery waiting to happen! Please be sure to go to the Research tab and complete the Getting to know your dog survey, where you can answer questions about your dog’s current weight and body shape. This information will inform our ongoing research into the genetics of size and weight in dogs.
Haplotypes Revealing your dog’s ancient heritage
Haplotypes are particular DNA sequences that are inherited entirely from a dog’s mom (maternal) or dad (paternal).
Because they are inherited whole, your dog and his or her mom share the exact same maternal haplotype. If you have a male dog, your dog and his dad share the exact same paternal haplotype (female dogs don’t inherit paternal haplotypes).
Because most breeds were started with only a few individual dogs, many breeds are dominated by only one or a few haplotypes.
Haplogroups Revealing your dog’s ancient heritage
Haplogroups are groups of similar DNA sequences (called haplotypes) that are inherited entirely from the mother (maternal) or father (paternal) and don’t get shuffled up like other parts of your dog’s genome.
These groups all originally descend from one male or female wolf, usually one that lived tens of thousands of years ago. Because they are inherited whole and not shuffled like other DNA, they can be used to trace the ancestral routes that dogs took around the globe en route to your home.
Only male dogs have paternal haplogroups because they are determined by the Y chromosome, which only male dogs have. Both males and females have maternal haplogroups, which come from a part of DNA called the mitochondrial DNA.
Breed analysisBreed analysis is based on comparing your dog’s DNA with the DNA of dogs from over 350 breeds, types and varieties. How are Walter's ancestors represented in his DNA?
All dogs are related and share some DNA. Siblings share lots of their DNA (half of it in fact), cousins share a bit less (an eighth), and so on. Because dog breeds are made up of a closed group of dogs, all dogs in that breed share a lot of their DNA, typically about as much as second cousins, though it varies by breed. Different breeds that are closely related share somewhat less DNA, and dogs from very different breeds share even less DNA (but still much more DNA than either dog shares with a cat).
DNA is inherited in pieces, called chromosomes, that are passed along from parent to offspring. Each generation, these chromosomes are broken up and shuffled a bit in a process known as recombination. So, the length of the segments your dog shares with his ancestors decreases with each generation above him: he shares longer segments with his mom than his grandma, longer segments with his grandma than his great-grandma, and so on.
How does Embark know which breeds are in Walter?
We can use the length of segments Walter shares with our reference dogs to see how many generations it has been since they last shared an ancestor. Long segments of DNA that are identical to known purebred dogs tell Embark's scientists that Walter has, without a doubt, a relative from that breed. By testing over
200,000 genetic markers, we build up his genes one DNA segment at a time, to learn the ancestry with great certainty. Other dog DNA tests look at many fewer genetic markers and have to take a guess at breed ancestry based on that. What does this mean for Walter's looks and behavior?
Look closely and you'll probably find Walter has some physical and/or behavioral resemblance with his ancestor's breeds. The exact similarity depends on which parts of DNA Walter shares with each breed. Some traits associated with each breed are listed in the Breed & Ancestry section of our website. Embark will tell you even more about Walter's traits soon!
P.S. In a small proportion of cases, we find dogs that don’t share segments with other dogs we have tested, indicating the presence of a rare breed that is not part of our reference panel or possibly a true "village dog" without any purebred relatives at all. In these rare cases we contact the owner to find out more and let them know about their unique dog before they get their results. With this in-depth detective work,
we are pushing science forward by identifying genetically unique groups of dogs. Still have questions? Unresolved? Supermutt? Yes! Some dogs descend from other dogs that were themselves mixed breed. These other dogs can give small contributions to the ancestry of your dog, so small that they are no longer recognizable as any one particular breed. We call this portion unresolved or “Supermutt” since it confers super powers! Just kidding. But we do think supermutts really are super!
For Walter we have been able to go further, and identify some of the breeds that
we think may have been part of his heritage and have contributed to the Supermutt portion of his genome. We cannot be sure, given how little of their DNA has carried down to Walter, but we thought you might like to know our best guess anyway!
Likely breeds that contribute to Supermutt:
What are “Dogs Like Walter?”
“Dogs Like Walter” are based on the percentage of breeds the two dogs have in common. For example, two dogs that are both 27% Golden Retriever and 73% Poodle will have a score of 100%. Sometimes dogs with high scores look alike, and sometimes they don’t — either way the comparison is based on each dog’s unique DNA, which is much more accurate than judging by looks.
“Walter is famed for his "Dorito ears", long legs and butt swirls. He loves all of his toys, but his favorite has been his duck that he tosses around the room when he's feeling rowdy. His favorite game is wrestling, whether it's with other dogs or any human around. When Walter is feeling blue he gives a big loud sigh just to let everyone know.”
This dog has been viewed and been given 0 wags
Genetic Breed Result Boxer
Developed in Germany, the Boxer is a popular family dog: patient, loyal and smart-requiring lots of exercise and proper training. For active families or owners looking for a rambunctious jogging buddy, Boxers may be the perfect breed. Boxers delight their humans with their sense of humor and affectionate nature.
Learn More
American Pit Bull Terrier
The American Pit Bull Terrier originated in the British Isles and descends from the Mastiff-type dogs introduced to England in antiquity. The breed was brought over to the United States by English immigrants in the 1800s, and quickly became one of the most popular and widespread breeds there.
Learn More
Chinese Shar-Pei
Few dog breeds are more recognizable than the wrinkly Chinese Shar-Pei. This Chinese breed is often compared to a hippopotamus due to its thick muzzle. They also have a characteristic rough, bristly coat, which is how the breed got its name (“Shar-Pei” means “sand skin”). Despite their goofy appearance, Shar-Peis are serious, independent dogs who will loyally protect their owners.
Learn More
Miniature Pinscher
The Miniature Pinscher is a small breed of dog originating from Germany. The breed's earliest ancestors may have included the German Pinscher mixed with Italian greyhounds and dachshunds.
Learn More
Genetic Stats
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Dogs Like Walter
Discover dogs who share a similar breed mix to Walter. A higher score means the two dogs have more of their breed mix in common. A score of 100% means they share the exact same breed mix!
Click or tap on a pic to learn more about each dog and see an in-depth comparison of their DNA, breeds, and more.
Building blocks of life
See which breed every part of Walter’s DNA comes from!
Genes from your dog’s breeds serve as the building blocks to creating your unique pooch
Dogs have 39 pairs of chromosomes, almost double humans who have 23. 38 of those pairs are the same for all dogs while the 39th is the sex chromosomes - two X’s for females and one X and one Y for males. One copy of each chromosome came from your dog’s mother and one from your dog’s father. Each copy contains between 24 million and 123 million bases, or letters of DNA code, for 2.5 billion total letters inherited from each parent. This chromosome illustration shows a representation of each of your dog’s 38 pairs of chromosomes (excluding the X and Y sex chromosomes).
Because the members of a breed have similar stretches of DNA, we can use our 200,000+ genetic markers to determine what part of each chromosome in your dog came from what breed. For each pair of chromosomes, your dog’s mom and dad each gave your dog one copy of that chromosome, for a grand total of 78 chromosomes. So if your dog’s mom was a poodle and dad was a schnauzer then the painting would show one complete poodle and one complete schnauzer chromosome for each pair. The more complex your dog’s ancestry, the more complex the painting, as in each generation recombination (the splitting apart and "shuffling around" of genes between paired chromosomes) mixes up bits of chromosome from grandparents, great-grandparents, and beyond.
Each trait your dog exhibits, such as fur shedding, is based on the letter at one or more locations in your dog’s genome. For example the location determining if your dog sheds their fur is located on chromosome 1. Some other traits, like size, are complexly inherited from many locations, including ones on chromosomes 1, 3, 4, 7, 10, 15, and more. Your dog looks the way it does not because of averaging or blending the breeds that form it, but because specific traits were inherited from specific breeds. That’s one reason your mix may look, act, and have certain health issues much more like one breed than another!
Explore Contact Us
Would you like more information? Have you found a lost dog wearing an Embark dog tag? You can contact us at:
Breed Reveal Video
Our algorithms predict this is the most likely family tree to explain Walter’s breed mix, but this family tree may not be the only possible one.Learn more about Embark
Explore
Through Walter’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.
C2 C19 C2
C2 is a very old female lineage found more commonly among English Setters, English Bulldogs, and American Eskimo Dogs. We also see C2 in village dogs in South Asia. Rather than having a few characteristic breeds representing this lineage particularly well, it is present in a few uncommon individuals of many different breeds. Unlike some European breed lineages that have seen skyrocketing popularity along the path to the modern dogs we see today, C2 tends to reflect the deep history of man's best friend.
C19
Part of the C2 haplogroup, this haplotype occurs most commonly in Boxers. It’s a rare find!
Some other Embark dogs with this haplotype:
You can often find his haplogroup in the lovable English Bulldog.Learn more about Embark
Explore
Through Walter’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.
A1a H1a.15 A1a
Some of the wolves that became the original dogs in Central Asia around 15,000 years ago came from this long and distinguished line of male dogs. After domestication, they followed their humans from Asia to Europe and then didn't stop there. They took root in Europe, eventually becoming the dogs that founded the Vizsla breed 1,000 years ago. The Vizsla is a Central European hunting dog, and all male Vizslas descend from this line. During the Age of Exploration, like their owners, these pooches went by the philosophy, "Have sail, will travel!" From the windy plains of Patagonia to the snug and homey towns of the American Midwest, the beaches of a Pacific paradise, and the broad expanse of the Australian outback, these dogs followed their masters to the outposts of empires. Whether through good fortune or superior genetics, dogs from the A1a lineage traveled the globe and took root across the world. Now you find village dogs from this line frolicking on Polynesian beaches, hanging out in villages across the Americas, and scavenging throughout Old World settlements. You can also find this "prince of patrilineages" in breeds as different as German Shepherds, Golden Retrievers, Pugs, Border Collies, Scottish Terriers, and Irish Wolfhounds. No male wolf line has been as successful as the A1a line!
H1a.15
Part of the large A1a haplogroup, this haplotype is found in village dogs from across the globe (outside of Asia). As for breeds, it is primarily seen in German Shepherds, Labrador Retrievers, Nova Scotia Duck Tolling Retriever. It is by far the most common haplotype in German Shepherds.
Some other Embark dogs with this haplotype:
Dogs with A1a lineage travelled during European Colonial times.Learn more about Embark | 18,970 | 7,785 | 45,240.464997 |
warc | 202143 | 29 Aug 2011 Black Activists Repudiate Al Gore’s Race Card Rhetoric in Support of More Regulation Washington, D.C. – Members of the Project 21 black leadership network are condemning former vice president Al Gore’s attempt to injected race into the debate over emissions regulations by comparing those opposed to further regulation with opponents of the civil rights movement.
“Coming during the week of the planned Martin Luther King Jr. National Memorial dedication, the so-called inventor of the Internet’s comments are off the deep end,” said Project 21 spokesman Horace Cooper, who is also a senior fellow with the Institute for Liberty. “Equating sincere disagreements over a scientific theory with lynching and Jim Crow isn’t just off base — it denies history and is a slap in the face of all Americans who came together to end racism and bigotry.”
In an interview broadcast on UStream late last week, Gore said advocates of increased emissions regulations need to “win the conversation on climate.” In comparing his critics to people who opposed civil rights laws, Gore said: “[T]here came a time when racist comments would come up in the course of the conversation and in years past they were just… natural. Then there came a time when people would say, ‘Hey, man why do you talk that way, I mean that is wrong. I don’t go for that, so don’t talk that way around me. I just don’t believe that.’ That happened in millions of conversations and slowly the conversation was won… And we have to win the conversation on climate.”
When interviewer Alex Bogusky suggested it was hard to difficult to respond to critics of increased emissions regulation, Gore replied: “It is no more difficult that it was for southerners to talk about the evil of racism.”
Project 21 spokesman Jerome Hudson noted: “When Al Gore compares those who question his perception of man-made global warming to racists and segregationists in an attempt to ‘win the conversation,’ he reveals a disturbing desperation that not only alienates him from the mainstream but marginalizes his logic and nullifies his already flailing credibility.”
Beyond the absurdity and offensive nature of Gore’s statement, Project 21 experts also point out that Gore’s own family history and the expected extent of his regulatory agenda marginalize his credibility when he attempts to embrace the civil rights movement.
“Al Gore’s grounding in reality — or lack of it — is astounding,” said Project 21 spokesman Cherylyn Harley LeBon. “And Gore’s memory appears selective. While suggesting the attitudes instilled by the civil rights movement be similarly used to advance an idea he supports, but many scientists argue is not based in science or proven policies, Al Gore seems to have conveniently forgotten his own family’s history. His father, Senator Al Gore Sr., voted against the Civil Rights Act of 1965 and has the shameful distinction of participating in one of the longest filibusters in the history of the U.S. Senate opposing civil rights legislation.”
Project 21 fellow Deneen Borelli added: “The real race problem associated with Gore’s assault on fossil fuels is that increased regulation leads to higher energy prices — a regressive tax that specifically harms low-income black families. While members of the elite such as Al Gore can afford energy at virtually any price, skyrocketing fuel and utility costs reduce the standard of living for hardworking American families. High energy prices also drives jobs overseas, contributing to slower economic growth and high unemployment.”
Project 21, a leading voice of black conservatives since 1992, is sponsored by the National Center for Public Policy Research (http://www.nationalcenter.org). | 3,930 | 1,916 | 7,609.759916 |
warc | 202143 | Research
Many disorders of the visual system impair spatiotemporal processing. It is thought that this is due to abnormalities in the cortical network. In primate cortex, visual information is encoded in multiple functionally specialized areas which are connected to hierarchical processing streams, specialized for object recognition and spatial relationships. The structure and physiology of the synaptic circuits that underlie these functions are incompletely understood. Recent advances in labeling, recording and manipulating the activity of distinct types of neurons suggest that the mouse visual system in a suitable model for unraveling the underlying network. An important question is whether the mouse visual cortex is similar to that of primates and contains multiple modularly organized areas that are linked to distinct processing streams. If so, another important question is how these modules, areas and processing streams work together to create a unified representation of the world that can be flexibly changed by internal representations of the world to optimally guide behavioral goals.
To investigate these questions the Burkhalter laboratory employing a combination of anatomical, physiological and optogenetic techniques. For delineating area maps we are studying the regional distribution of molecular markers and use topographic mapping of connections and physiological recording of visual receptive fields. Multi-color viral tracing methods are employed to study the anatomical organization of cortical streams and areal hierarchies. Single unit recordings with electrode arrays are used to determine whether the areas are connected to different streams that process distinct visual information. To study the neuronal composition of feedforward and feedback circuits between lower and higher cortical areas we are using neuronal tracers and cell-type specific markers of excitatory and inhibitory neurons. For determining the mechanisms of synaptic transmission in interareal circuits we are using laser photo stimulation of channelrhodopsin labeled feedforward and feedback connections and whole cell recording of synaptically connected inhibitory and excitatory neurons in brain slices.
The results show that mouse visual cortex contains at least 11 visual areas, which are linked to distinct hierarchically organized streams that preferentially process spatial and temporal information. Laboratory findings demonstrate that the mouse and primate visual systems share fundamental similarities, suggesting that the mouse is a suitable model for mechanistic studies of neurological disorders in humans.
Selected publications D’Souza, R. D., Bista, P., Meier, A. M., Ji, W. & Burkhalter, A., (2019) Spatial clustering of inhibition in mouse primary visual cortex. Neuron. 104: 588-600.e5 Ji, W., Gamanut, R., Bista, P., D’Souza, R.D., Wang, Q., & Burkhalter, A.(2015) Modularity in the organization of mouse visual cortex. Neuron.87:632-643. Yang, W., Carrasquillo, Y., Hooks, B.M., Nerbonne, J.M., & Burkhalter, A.(2013) Distinct balance of excitation and inhibition in an interareal feedforward and feedback circuit of mouse visual cortex. J. Neurosci. 33:17373-17384. PMID 24174670. Wang, Q. & Burkhalter, A.(2013) Stream-related preferences of inputs to he superior colliculus from areas for dorsal and ventral streams of mouse visual cortex. J. Neurosci. 33:1696-1705. PMID: 23345242. Wang, Q., Sporns, O., & Burkhalter, A.(2012) Network analysis of corticocortical connections reveals ventral and dorsal processing streams in mouse visual cortex. J. Neurosci. 32:4386-4399. PMID: 22457489. Carrasquilo, Y., Burkhalter, A., & Nerbonne, J.M. (2012) A-type K+ channels encoded by Kv4.2,Kv 4.3 and Kv4.1 differentially regulate intrinsic excitability of cortical pyramidal neurons. J. Physiol. 590:3877-3890. PMID: 22615428. Wang, Q., Gao, E., & Burkhalter, A.(2011)Gateways of ventral and dorsal streams in mouse visual cortex. J. Neurosci. 31:1905-1918. PMID:21289200. Gao, E., DeAngelis, G.C., & Burkhalter, A.(2010) Parallel input channels to mouse primary visual cortex. J. Neurosci. 30:5912-5967. PMID: 20427651. Burkhalter, A.(2008) Many specialists for suppressing cortical excitation. Front. Neurosci. 2:155-167. PMID: 19225588. Gonchar, Y., Wang, Q., & Burkhalter, A.(2007) Multiple distinct subtypes of GABAergic neurons in mouse visual cortex identified by triple immunostaining. Front. Neuroanat.1: 1-11. PMID: 18958197. Wang, Q., & Burkhalter, A.(2007) Area map of mouse visual cortex. J. Comp. Neurol. 502:339-357. PMID: 17366604. Education
1973 MS, Zoology, University of Zurich, Switzerland
1977 PhD, Neurobiology, University of Zurich, Switzerland
Selected honors
2011, Student invited Seminar UC San Diego Neuroscience Graduate Program
2013, Seminar Series. Wiersma Visiting Professor, California Institute of Technology, Pasadena, CA | 4,901 | 2,210 | 10,822.117647 |
warc | 202143 | Thursday, February 18, 2021
Superpowers are relative:
If an ordinary individual was transported from our universe to the Marvel or DC Universe, they might have a superpower upon arrival there.
Without being changed in any way, they would have the superpower of genre transcendence. They would be more likely to be free of the infuriating conformity and stupidity of these fictional cinematic and comic book universes.
There is no good reason for pain:
Pain is random, absurd, and unnecessary. That doesn't prevent there being an infinite amount of it. I call this pessimistic view of reality the Tortureverse.
Some say that pain is a powerful evolutionary tool, that is said to "serve a purpose" by "protecting" an organism from placing itself in dangerous situations.
This view is also false.
In an infinite and endless universe, it would be perfectly possible to achieve the same results without pain. There would only be gradients of more or less pleasure. This would work slower than gradients of pain and pleasure, but that doesn't matter in an infinite universe.
Pain is a purely parasitical process, an existentially useless curse.
Evolution selects against evolution:
Maintaining existing genes must be as important as evolving new genes.
This prevents better systems from evolving as fast as they should. Anthropically speaking, that may be why we are at the very bottom of an infinitely complex omniverse.
Waiting for the first true sign of progress:
That would be a way for almost anyone to make money, except for people who should be locked up anyway. Right now we're heading in the opposite direction.
Imagine software that actually helps you, instead of helping you make things more complicated.
* A science fiction story about a low resolution human mind scan method. No technical details on how it works. * A podcast with Mat Pesch ...
Actually, we would settle just for photos of the Rundown. As you may know, the only image is a rendering of the main room that was submitted... Three days ago, on December 7, 2019, Flag Land Base Day was celebrated (Confusingly, some websites list December 6 instead). This date on th... L. Ron Hubbard wrote and talked extensively about thousands of previous lifetimes as if they actually happened, and as if we all experienced... | 2,306 | 1,242 | 4,238.806763 |
warc | 202143 | World Breastfeeding Week-2021 Protect Breastfeeding: A Shared Responsibility
The Department of Community Medicine, KIMS organised various community outreach and awareness programmes in the Urban Health Training Centre, Niladri Vihar and Routine Immunisation Clinic, KIMS on the occasion of World Breastfeeding Week-2021, which is being observed from 1
st to 7 th August, 2021.
The programmes were conducted in tune with the event objectives of the year set by World Alliance for Breastfeeding Action (WABA). The interns, Dr. Puja, Dr. Rahul Sahoo, Dr. Rajesh Nanda, Dr. Rahul Goswani, Dr. Pratikshya, Dr. Stitipragyan, Dr. T. Sai and Dr. Zahar along with the postgraduate students were actively involved.
Dr. Ansuman Kar and Dr. Tapas Ranjan Senapati under the guidance of Dr. Ipsa Mohapatra, Associate Professor in the UHTC carried out the week-long Community Awareness campaigns in the slums of Niladri Vihar, where the lactating and nursing mothers were explained about the benefits and need for continued breastfeeding . As Maternity Protection is key to enable breastfeeding and empower parents for a successful implementation of recommended breastfeeding practices, regular checkups and health education activities were also carried out in the slums.
At the Immunization Clinic, poster presentations were done by the interns, Dr. Rubina Pany, Dr. Rutuparna Panda, Dr. Sahil Godara, Dr. Samikshya Gupta, Dr. Vishal Chaudhury and Dr Vivek Kudawla. Postgraduate students, Dr. Smriti Madhusikta and Dr. Pragyan Paramita under the guidance of Dr. S. Suneeti Kanyari, Asst. Professor also presented posters on the theme of the year. As pregnancy and lactation make working women and their families vulnerable, expectant and nursing mothers require special protection to prevent any possible damage to their infants’ health. They also need adequate time to give birth, to recover, and to nurse their children.
The events were supervised and attended by Prof. Dr. B. K. Behera, HOD, Community Medicine; Prof, Dr, Sonali Kar, Prof, Dr, S. R. Nayak, Dr. Alpana Mishra, Dr. Krishna Mishra, Dr. Snigdha Singh, Dr. Bidisa Sarkar, Dr. Aparajita Mishra, Dr. B. Laksmi Priyanka, Dr.Varsha Srivastava. The events were supported by Mr.Swarup Roy Choudhury, Ms. Shradhanjali Nayak, Mr.Surjya Narayan Mohapatro, Ramesh, Mrs. Nibedita Tripathy and Ms Nilima. | 2,356 | 1,213 | 4,550.789777 |
warc | 202143 | Arriving into presence In this moment, this place, this community, drawing awareness to breath Extending the exhale a bit longer than the inhale Moving from what feels good right now Coordinating breath and movement Drawing attention to breath, more specifically the exhale Take a breath Reach and ground and stretch and bounce Notice what you notice And come back to breath Notice where the inhale ends and the exhale begins The spaces between the two Arriving into bodily presence And as we arrive We turn Turning toward instead of turning away Turning toward what frightens us Turning toward in a full bodied way Turning toward vibrant, entanglement with the world Turning away from despair and toward the work of hope Turning toward the darkness as our colleagues in palliative care turn toward death and grief and loss with deep care Turning toward wellbeing times of times of transition. And as we turn we center, decenter, and re-center Centering livability and Decentering the human in a continuum of life
“we can craft other visions that will be conducive to the long-range survival of humans and of the other life-forms, biological and artificial, with whom we share the planet and ourselves”katherine hayles
Centering livability means
Making a radical commitment to shifting and sharing power (and speaking as a white, cis-gendered, heterosexual daughter of conquest this is all the more vital) Centering indigenous voices each day in what I choose to pay attention to and how we pay attention Centering our Black and queer and non-binary communities, work, and voices Centering spirit and grace with unapologetic loving kindness and deep awareness of relationally to place and to each other Centering our plant friends and animal teachers Arriving, Turning Toward, and Centering/Decentering are some of the meta-practices I’ve developed during the establishment of the Livable Futures network (more about that here). It is also an expression of the specific space of dance and choreography, always concerned with motion and the way in which the body is our means of orienting ourselves to the world (makes me think of a beloved text, Queer Phenomenology by Sara Ahmed). | 2,201 | 1,096 | 4,379.909672 |
warc | 202143 | Alpha Brain and Modafinil are both nootropics, but Alpha Brain is 100% natural and Modafinil is a prescription-only drug used to treat narcolepsy, a condition that triggers victims to drop off to sleep at inconvenient times. While both compounds have similar effects in terms of promoting wakefulness, increasing concentration, and enhancing working memory, they are a world apart in regards to adverse effects and safety.
In this section, we'll give you the low-down on these 2 heavyweights in the wise drug scene. Modafinil is a miracle drug that functions as a stimulant when taken 'off-prescription' by healthy people. It enormously increases concentration and awareness while providing a big increase in working and episodic memory [11] (Onnit Master Reward Level).
So how does Alpha Brain compare? One dosage of Alpha Brain gives you:6+ hours of enhanced concentration and focus. Improved verbal recall and executive functioningSignificantly enhanced recent spoken memoryBetter mental processingHeightened 'flow state' (the sensation of being 'in the zone') While Modafinil provides:12+ hours of significantly increased attentivenessBoosted concentrationEnhanced alertness [13] Improve learningOptimized working memory [14] In terms of cognitive benefits, Alpha Brain and Modafinil resemble night and day the natural substances discovered in Alpha Brain simply can't compare to Modafinil in terms of potency, duration, and impact.
Although there's never been a peer-reviewed study into exactly what occurs when healthy individuals take Modafinil as a nootropic, one research study looked into what takes place when Modafinil is given to patients who have been improperly diagnosed with narcolepsy, i. e. non-sufferers (Onnit Master Reward Level). It found that Modafinil triggers an entire host of unforeseen side effects including [15]: HeadachesNauseaAnxietyInsomniaLumbagoDiarrheaDyspepsiaRhinitisVertigoThese reported adverse effects were moderate, but are necessary to learn about prior to you decide whether to take Modafinil.
It consists of no precursor molecules for compounds that are known to induce addiction. Nevertheless, it been shown to operate as a reinforcer and have abuse capacity under particular scenarios, especially when taken at a high dosage. In one case, a guy with bipolar affective disorder established Modafinil reliance and later, had hypersexuality, when he increased his dosage of Modafinil from 400 to 1,000 mg/day [16].
Modafinil is the supreme clever drug since, quite honestly, absolutely nothing matches its potency and effectiveness as a wakefulness-promoting representative (Onnit Master Reward Level). However, it comes with major side effects to boot and should not be taken gently. Alpha Brain, on the other hand, offers a solid 4-6 hours of 'laser-sharp' focus and concentration and increases working memory with essentially zero negative effects.
When it pertains to efficiency supplements, a number of them concentrate on workouts, energy, weight loss, and so on. Onnit Master Reward Level. As it occurs, some have favorable side impacts that occur to be helpful however aren't necessarily the objective of the item. But what if you could take a supplement developed to enhance your mind? Enter Onnit's Alpha BRAIN, a nootropic supplement developed to assist you with memory, focus, and brainwave function.
If you're not familiar with nootropics, they're basically cognitive enhancers" wise drugs" that boost cognitive and executive function, memory, and motivation. Mind efficiency drugs, if you will. This means that the impacts of Alpha BRAIN can reach numerous areas of life and activities, from exercises and work conferences to school jobs, parties, and performances - Onnit Master Reward Level.
Alpha Brain by Onnit is one of the leading nootropics on the market. This brain supplement is developed to assist with focus, memory, and general brain health. An accredited drug-free product, Alpha BRAIN has actually evaluated safe when it concerns negative effects and drug tests. This suggests that you can take the supplement anytime and feel great that those random drug tests at your job won't be a concern.
In truth, Onnit Labs specifies that it's completely fine to take Alpha BRAIN together with coffee or caffeine due to the fact that Alpha BRAIN promotes your neurotransmitters directly and does not slow down your adrenal glands. Onnit Master Reward Level. Taking the supplement is basically like shifting your brain into the next gear, which sounds harmless and handy.
It's non-habit-forming, so there's no dependence issue or withdrawal if you do not take it. Alpha BRAIN is perfect for trainees, athletes, executives, those in the limelight or those who have social stress and anxiety, those who require psychological concentration and focus at work, those involved in competitors, efficiencies, and showsreally, anyone who experiences psychological sluggishness, brain fog, or tiredness.
In spite of the fact that Onnit states that Alpha BRAIN must have little to no negative effects, some users have actually noticed problems such as nausea, vomiting, diarrhea, cramping, headaches, light-headedness, lightheadedness, brain fog, weakness, fatigue, sweating, rapid heartbeat, sleeping disorders, and tremblings. Onnit Master Reward Level. While it's totally possible that a really slim minority is impacted negatively, it's sufficient for the product to have practically an equivalent ratio of one-star to five-star reviews on Amazon.
Could this have something to do with the product quality coming directly from the seller? Possibly, although the product is offered just by a third-party seller on Amazon and not straight. On the flip side, the users who reported favorable results really like Alpha BRAIN. Lots of state that they notice improved moods, are able to focus much better, and can keep in mind more than ever beforeand some say it's a certain game-changer.
Whether Alpha BRAIN genuinely works is largely up to each person. Especially if you understand you're delicate to medications and supplements, it's most likely best to start with a smaller sized dose and boost slowly to test the impacts. Maybe this is one supplement that some users need to change to, however there's just one way to learn for sure.
Get a complimentary bottle no string attached!CLAIM YOUR COMPLIMENTARY BOTTLE! Vegan-friendly, Caffeine- and gluten-free Alpha BRAIN is made with a host of natural and non-GMO components, some of which include: Bacopa Feline's claw Oat straw Huperzine A L-Tyrosine L-Theanine L-Leucine Vinpocetine Pterostilbene In some cases utilized in Ayurvedic medication, bacopa monnieri is an herb that improves cognition, memory disorders, and stress and anxiety, which is where Alpha BRAIN gets some of its cognitive enhancement and mood-boosting residential or commercial properties. Named for its claw-like thorns (and they scratch simply like a cat's claws!), cat's claw offers benefits such as immune boosters and antioxidant effects. Possible adverse effects can include nausea, vomiting, dizziness, headaches, and diarrhea. Oat straw advantages include increasing energy, reducing anxiety and anxiety, increasing cognition, decreasing inflammation, and improving performance in lots of locations. Nevertheless, surpassing the recommended dose may decrease cognitive enhancement.
benefits. Onnit Master Reward Level. Without getting excessive into the science of it, Huperzine A is a natural compound that is used to deal with memory problems and increase alertness. It is often used in the treatment of Alzheimer's and other age-related memory conditions. As for adverse effects, it appears that Huperzine A can trigger queasiness, throwing up, diarrhea, sweating, cramping, muscle twitching, and uneasyness. L-tyrosine increases dopamine and memory; L-theanine lowers anxiety and depression, prevents and treats.
Alzheimer's and ADHD, and enhances psychological efficiency and attention; L-leucine boosts energy and metabolic functions. Vinpocetine, a chemical reproduction of an herb, might enhance memory and concentration by increasing blood flow to the brain. It likewise avoids Alzheimer's and boosts processing abilities. | 8,234 | 3,760 | 17,987.78617 |
warc | 202143 | Abstract
The main purpose of the project was to analyze and identify substitution of process heat from fossil fuels as currently used in industry with electricity-based heat. The project has analyzed how processes in specific industries are best converted to electricity-based heating, and as a consequence may increase efficiency and flexibility. Electrification can take place indirectly by conversion to fuels based on power-to-X, or directly by converting to electricity-based heating, by heat pumps or electric heating. This project focuses on the latter. Heat pumps are highly efficient, but are limited by e.g., temperature, while electric heating provides a potential for flexibility, in particular when using storage. The project includes detailed analyses of processes found in pectin production, milk powder production, brewing, plastics production and steam laundry. These cases may be seen as representative for a significant share of the manufacturing industry and involve options for process integration as well as high temperature processes.
Throughout the project, a procedure for investigating electrification potential has been developed. This involves mapping the individual energy-demanding processes, analyzing the potential for heat recovery by process integration, assessing the potential for using alternative technologies, defining electrification scenarios, calculating electrified process scenarios with a focus on energy, economics and CO2 emission. The method has been continuously developed throughout the project but has been used on the basis of the same basic idea. The method has been used both for the overall analysis of the industry and for the individual cases.
The presented analyzes show that electrification is possible and technically feasible for a significant part of the Danish industrial process heating needs. It has been found that the need for fuels can be reduced to 10 % of the current use, while the remaining use can be electrified. This in turn will reduce the need to about two-thirds of the current one.
For some of the case studies, e.g. milk powder and pectin production, full electrification can take place through energy integration, use of mechanical steam compression, heat pumping and electric heating. Current heat pump technology allows temperatures up to 100 °C, but the technology needs further development for higher temperatures. From this perspective, the available low temperature sources for the heat pumps are also important, as temperature lift significantly affects the performance of the heat pump.
The project has contributed with overall electrification plans for some of the cases, primarily pectin production. Part of this has involved assessment of technology from SAN Electro Heat for direct heating of processes that cannot use heat pumps and the need for further development of these.
For Labotek, a new solution has been developed during the project for drying plastic granulate with recovery of excess heat. This solution is implemented in Labotek’s products and in operation in the industry. A further development of the solution with a heat pump has been analyzed and could provide further process improvement.
The project has thus found a significant potential for electrification in Danish industry. The project also includes an analysis of bottlenecks in the conversion to electrification, which should be included in the picture. These are grouped as being economic, technical, organizational or risk-related. They include technical limitations in current heat pump technology and costs of conversion, but also requirements for security of supply and the company’s willingness to convert to a large extent and to use less well-known technology.
For industrial production, the potential for sector coupling by using electricity flexibly is less clear. The industry will most often need to utilize the capacity for process heating fully with a high number of operating hours per year, but for batch processes and by investing in extra capacity, it is possible to utilize the potential for energy storage provided that it does not affect the final product, e.g. due to temperature changes.
From an economic perspective the electrification is feasible for a number of the analyzed cases. However, full electrification will require further development of technology and frame conditions related to investment and operating cost as well as possible subsidies and taxation related to greenhouse gas emission. In this respect, it is important to keep in mind that electricity production in Denmark presently causes greenhouse gas emissions, and that sustainable electrification requires significant development of the electricity system.
Original language English
Place of Publication Kgs. Lyngby Publisher Technical University of Denmark Number of pages 348 Publication status Published - 2021 | 4,907 | 2,036 | 11,758.965128 |
warc | 202143 | Photo by Mark Fletcher-Brown/Unsplash
Jack Canfield of
The Secret and the Chicken Soup for the Soul book series fame said: What is the whybehind everything you do? When we know this in life it is very empowering and the path is clear.
I tend to agree. When you know what drives you, everything else has a way of taking care of itself.
But how do you find your purpose?
Doesn’t it require hundreds of hours meditating, journaling, and doing weird exercises with weird people at sketchy home-based workshops?
Here are some thoughts on finding your purpose, based on my own experience.
Ask Yourself Whether Your Purpose Needs to be Found
This may seem an odd place to begin.
But it’s a question worth asking.
Does your purpose need to be discovered, or is it innate? Has it been with you since the moment you were born?
As my mother will testify, I was creative since the moment I was born.
I would follow along with the arts and crafts segments on children’s programming (like
Sesame Street and Mr. Dressup). Even if I didn’t have the right materials, I’d do the best I could with what I had around.
Back then, if you had asked me what I wanted to do when I grew up, I would have told you “I want to be a firefighter and an artist”.
I didn’t have just one aspiration – I had two!
My desire to be a hero subsided somewhat as I began learning about the real dangers of the world (I remember being stung by a jellyfish in Malaysia), but indeed, I did grow up to be an artist in a variety of capacities.
When I was a child, I imagined being a visual artist (painter/illustrator) primarily. But in my teens, I got into music, and that brought with it a new set of responsibilities like building websites, blogging, making videos, and more.
Before I knew it, I started plunging into the world of new media (which probably means something different now, but at the time it was video games, podcasting, social media, and composition), and today, most of the work I do falls under that category.
This isn’t to say new passions won’t begin to reveal themselves as I continue to live, explore, grow, and experiment.
But I never had to spend a lot of time figuring out that I wanted to be creative in some capacity. I just was.
My greatest challenge, if anything, was learning to cultivate focus. My creativity found so many expressions, I had no idea which direction to go in!
So, that begs the question:
Does your purpose need to be found? Experiment Plenty
I would never discount the importance of experimentation as applied to self-discovery.
See, many people are in fact too afraid to try. They
say they like to try new things but find themselves watching the same Netflix shows, hanging out at the same coffeehouses, and going to the same sandwich shop for lunch every Friday.
Human beings are creatures of habit, plain and simple. It takes something to break out of our routines.
To some extent, this might be easier to do when you’re younger, simply because people around you can accept the notion that you might still be “figuring yourself out.”
Post 35, a lot of people will start asking accusatory questions like:
“What are you doing with your life?”
PsychCentral says:
Changing a behavior is not done simply or overnight. If something took 20+ years to learn, it’s likely that it will take an equally significant (if not the same) amount of time to “unlearn” or to change that behavior or routine.
Ultimately, though, I don’t think we need to complicate matters.
We just need to set aside some time in our schedules to try things and be deliberate about following through.
You could set aside an hour every Friday. Or you could take advantage of evenings and weekends. Whatever works for you!
If you think calligraphy might be interesting to take up, give it a try (I did).
If you think skateboarding could be your next hobby, give it a try (I did).
If you think wood carving could be a lot of fun, go for it (I did).
By the way, I didn’t stick to any of those things. But they continue to fascinate me, and I still watch videos of people engaged in these activities (when I can't go and watch in real life).
The point is that I followed my instincts and I started to make sense of what worked and what didn't.
Will you follow your instincts?
Pay Attention to Your Instincts
In some ways, this goes back to the question posed earlier (does your purpose need to be found?).
And it also connected to the previous point on experimentation.
I’d like to share a story to illustrate why you should pay attention to your instincts.
About 13 years ago, I went to see a counsellor about my anxiety.
In retrospect, though, I wasn’t just trying to figure out how to heal or cope with a condition. I was also trying to figure out my identity – what I was here to do.
I remember being asked what I wanted to accomplish during one counselling session.
And I didn’t have any articulate, detailed answers. I just said I wanted to inspire people.
What intrigues me about my answer is that today,
my mission is to inspire creatives and creators.
13 years later, all that’s really changed is my targeting. And even that hasn’t really changed because I see everyone as a creative.
It’s just that, 13 years ago, I didn’t trust myself or my answer. I thought I was missing something. I assumed that everyone else had a better answer, and I was somehow defective.
Well, maybe I was missing
something (the “creative and creator” part). But in essence, I had a good feel for what was on my heart already. My instincts weren’t miles off from the bull’s eye.
We often feel as though we should be toiling to discover our purpose. We assume need to work harder, try harder, think harder.
Maybe our purpose is on the other side of letting go and listening to our souls.
Final Thoughts
Once you’ve identified your purpose, all other decisions concerning your life, your projects, your next actions become much clearer.
For those who know their purpose, waking up early, staying up late, sacrificing social outings, and other “unusual” behavior all seems normal.
All the while those without a purpose can’t imagine spending a minute more at a job they tolerate.
If you don’t know what your purpose is yet, start there. Once you’re clear on that, you will never feel like you’re sacrificing. You will do whatever it takes to make a difference in the lives of the people you’re serving.
Sources PsychCentral – Changing Our Routines and Habits, https://psychcentral.com/lib/changing-our-routines-and-habits#1 | 6,746 | 3,215 | 13,578.02986 |
warc | 202143 | Using a 2×2×2 experimental design, the effects of situational and individual variables on individuals' intentions to act unethically were investigated. Specifically examined were three situational variables: (1) quality of the work experience (good versus poor), (2) peer influences (unethical versus ethical), and (3) managerial influences (unethical versus ethical), and three individual variables: (4) locus of control, (5) Machiavellianism, and (6) gender, on individuals' behavioral intentions in an ethically ambiguous dilemma in an work setting. Experiment 1 revealed main effects for quality (...) of work experience, Machiavellianism, locus of control, and an interaction effect for peer influences and managerial influences. Experiment 2 showed main effects for all three situational variables and Machiavellianism. Neither experiment supported gender differences. Limitations, future research, and implications for management are discussed. (shrink)
Because higher education brings members of academic communities in direct contact with students, the reflective higher education student is in an excellent position for developing two important intellectual virtues: confidence and humility. However, academic communities differ as to whether their members reach consensus, and their teaching practices reflect this difference. In this essay, Ward Jones argues that both consensus‐reaching and non‐consensus‐reaching communities can encourage the development of intellectual confidence and humility in their students, although each will do so in (...) very different ways. (shrink)
Most explanations of beliefs are epistemically or pragmatically rationalizing. The distinction between these two types involves the explainer's differing expectations of how the believer will behave in the face of counter-evidence. This feature suggests that rationalizing explanations portray beliefs as either a consequence of the believer's following a norm, or part of a sub-intentional goal-oriented system. Which properly characterizes pragmatic believing? If there were pragmatic norms for believing, I argue, they would not be consciously followable. Yet an unallowable norm is (...) not a norm at all, and so I conclude that there are no such norms and that pragmatic believing is a sub-intentional, and not a norm-driven, process. /// La mayoría de las explicaciones de las creencias racionalizan de forma epistémica o pragmática. La distinción entre estas dos involucra las diferentes expectativas del que explica acerca de cómo se comportará el creyente frente a evidencia contraria. Este rasgo sugiere que las explicaciones racionalizadoras toman las creencias o bien como una consecuencia de que el creyente siga una norma, o bien como parte de su sistema subintencional orientado a fines. ¿Cuàl caracteriza de manera apropiada el creer pragmático? Aquí argumento que si hubiera normas pragmáticas para creer, no se podrían seguir conscientemente; sin embargo, una norma no seguible no es una norma en ningún sentido, por lo que concluyo que no existen tales normas y que el creer pragmático es un proceso subintencional y no un proceso guiado por normas. (shrink)
Shortly before his death, Richard Bader commented in this Journal on the dichotomy that exists within chemistry and between chemists. We believe that the dichotomy results from different goals and objectives inherent in the chemical disciplines. At one extreme are designers who synthesize new molecules with interesting properties. For these chemists, the rationale underpinning molecular synthesis is far less important than the end product—the molecules themselves. At the other extreme are the chemists who seek a fundamental understanding of molecular properties. (...) We suggest that the Quantum Theory of Atoms in Molecules, by virtue of the rich hierarchical structure inherent in the theory, offers a bridge through which to unite these two groups. However, if there is to be reconciliation, it falls to the theorists to develop “quantum mechanically” correct tools and concepts useful to the synthetic and applied chemist. (shrink)
Political argument and institutions in the UnitedKingdom have frequently been represented as the products of ablend of nationalistic conservatism, liberal individualism andsocialism, in which consensus has been prized over ideology. This situation changed, as the standard story has it, with therise of Thatcherism in the late 1970s, and again with the arrivalof Tony Blair's ``New Labour'' pragmatism in the late 1990s. Solidarity as an element of political discourse makes itsappearance in the UK late in the day. It has been most (...) stronglylinked to the Third Way debate, as framed most influentially inthe work of Prof. Anthony Giddens.In this paper we review the history and pre-history of the debateon solidarity in the UK, focussing mostly on its implications forwelfare state reform. In particular we discuss the proposals forthe long-term care of the Elderly issued by the Royal Commissionon long-term care in 1999. In this context we critically examinethe idea that solidarity is a new concept in British politicalculture, and that it is a concept which has real political ``bite''in the project of welfare reform. We examine this through aconsideration of Giddens's attempted synthesis of politicalargument and social theory. (shrink)
In _Bioethics in Context_, Gary Jones and Joseph DeMarco connect ethical theory, medicine, and the law, guiding readers toward a practical and legally grounded understanding of key issues in health-care ethics. This book is uniquely up-to-date in its discussion of health-care law and unpacks the complex web of American policies, including the Patient Protection and Affordable Care Act. Useful case studies and examples are embedded throughout, and a companion website offers a thorough, curated database of relevant legal precedents as (...) well as additional case studies and other resources. (shrink)
While the nature-grace debate rages in Thomistic circles, St. Bonaventure's theological anthropology and his theology of grace is paid much less attention, with the exception of his argument that Adam was created apart from gratia gratum faciens, or in modern terms habitual or sanctifying grace.1 For this position he has come under some scrutiny. John Milbank connects Adam's short time without habitual grace to Bonaventure's deficient understanding of illumination as proof of an incipient voluntarism and a suspect pure nature theology.2 (...) Turning Milbank upon his head, Fr. Christopher Cullen, S.J. defends the "suspended middle" in Bonaventure by appealing to Adam's creation without grace; human nature has a... (shrink)
SummaryIn this essay I critically discuss the views of Thomas Kuhn and Paul Feyerabend on the succession of scientific theories. I argue that, if Karl Popper's desiderata for theory succession are properly explicated, they constitute a basis for refuting the “incommensurability“ thesis of Kuhn and Feyerabend. Popper's claim that a new theory must constitute an “improvement” over the old implies that the new theory must be able to be interpreted as referring to most of the phenomena as its predecessor.RésuméDans cet (...) essai, je discute les vues de Thomas Kuhn et de Paul Feyerabend sur la succession des théories scientifiques. Je montre que si les desiderata de Karl Popper pour la succession des théories sont correctement explicités, ils constituent une base pour réfuter la thèse?incommen‐surabilité de Kuhn et de Feyerabend. Ľexigence de Popper selon laquelle une nouvelle théorie doit améliorer la précédente implique que la nouvelle théorie doit pouvoir être interprétée comme se référant à une plus grande part des phénoménes que ses prédécesseurs.ZusammenfassungIn der vorliegenden Arbeit werden Thomas Kuhns und Paul Feyerabends Auffassungen über die Frage, wie wissenschaftliche Theorien sich ablösen und folgen, erörtert. Ich zeige, dass Karl Poppers Forderungen für einen rationalen Theorienwechsel, wenn einmal richtig erläutert, eine Grundlage fiir die Widerlegung der Inkommensurabilitätsthese von Kuhn und Feyerabend lie‐fern. Proppers Forderung, dass eine neue Theorie gegenüber der alten eine Verbesserung darstellen müsse, impliziert, dass die neue Theorie so interpretiert werden kann, dass sie sich auf die meisten Phänomene bezieht, von denen auch in der Vorgängerin die Rede war. (shrink)
ABSTRACTShelley’s “Letter to Maria Gisborne” is a playful improvisational verse epistle, widely praised for its urbanity and its display of the poet’s invention. The verses turn on a catalogue of the collection of odd scientific and mechanical objects that Shelley found scattered around him in the place he composed the letter, the Livorno workshop of Gisborne’s son, a young engineer who was building a new-model steamboat at the time. In the context of that space, the poem reads as a response (...) to competing notions of invention. For Shelley, the engineer’s workshop is an attractive alternative to the poet’s tower—which was uncomfortably close to a Grub Street garret. Verbal and visual images of poets’ and scientists’ workshops, from Hogarth and Mary Robinson, to Joseph Wright of Derby and Frankenstein, illustrate the tensions embodied in the physical location and poetic performance of Shelley’s celebrated “Letter.”. (shrink)
Dark comedies invite us to laugh at something which is, at least ostensibly, not funny at all. They take an act or event that would, under most descriptions or presentations, invite pity or anger, and give it characteristics that invite amusement. It is essential to the humour of the kidnapping in The King of Comedy that it is a kidnapping. The immorality of this event is crucial to its humour.
Moral education is an important topic—both for moral philosophy and for the philosophy of education. Of the many questions that ought to be asked about moral education, certainly the following would be included in any reasonable list: What constitutes a moral education? How does one properly give someone a moral education? and Why provide persons with moral education? I have little to say about question. My main interest in this paper is in the third question, but I shall approach it (...) by first concentrating on question. What does a person have if he possesses a moral education? What is lacking and what is defective in an individual who does not have one? (shrink)
The proponents of the ‘vindication’ or ‘pragmatic justification’ of induction have attempted to show that induction will work if any method does. This in turn serves as grounds for their claim that we have everything to gain by using induction and nothing to lose. Hence, they conclude that it is rational to use induction. Their claim that induction will work if any mehtod does is based upon the following argument:If nature is uniform, induction will work. If nature is not uniform (...) and some other method works, the success of that method will then constitute a regularity to which induction can be successfully applied. In that case, induction will sanction the continued use of the successful method and hence will be successful as well. (shrink)
Introduction: Screen-based and mobile technology has grown at an unprecedented rate. However, little is understood about whether increased screen-use affects executive functioning, the range of mental processes that aid goal attainment and facilitate the selection of appropriate behaviors. To examine this, a systematic review was conducted.Method: This systematic review is reported in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement. A comprehensive literature search was conducted using Web of Science, MEDLINE, PsycINFO and Scopus databases to identify (...) articles published between 2007 and March 2020, examining the use of mobile technologies on aspects of EF in healthy adults aged 18–35 years. In total 6079 articles were screened by title, and 39 screened by full text. Eight eligible papers were identified for inclusion. Our methods were pre-registered on the PROSPERO international prospective register of systematic reviews.Results: A total of 438 participants were included across the eight studies. Five of the eight studies examined more than one EF. Five studies measured inhibition, and four studies measured decision-making. Smartphone use was negatively associated with inhibition and decision-making. Working memory performance was found to be improved by increased time engaging in video games and by refraining from smartphone use prior to bedtime. Quality assessments indicated high risk of methodological biases across the studies and a low quality of evidence for determining the relationship between technology use and executive functioning.Conclusions: This review highlights the scarcity of the literature in this area. It presents a call for rigorous and objective research to further our understanding of the impact of mobile technology on different aspects of executive function. (shrink) | 13,494 | 6,088 | 28,976.192838 |
warc | 202143 | The prediabetes It is a dangerous health condition for people, since in addition to warning about the potential appearance of diabetes, also poses a greater risk of developing diseases related to the heart. Of course, thanks to a diet with preponderance of vitamin D it is possible to control prediabetes. A study presented at… Continue reading This is the ideal vitamin D diet for prediabetes
The vaccination campaign before the Covid-19 continues to advance around the world. However the Coronavirus has not left our surroundings, there are still thousands of people suffering the consequences of the persistent Covid-19, something that thanks to the rehabilitation It could improve in those who, despite having passed the disease, still continue to suffer… Continue reading Olfactory rehabilitation, the new recommendation for patients with persistent Covid-19
The vitamin C It is essential for the Health of people. Its importance is verified by nutritionists, scientists and medical specialists. But also, in recent years it has emerged as the main element of beauty and care for skin. Its properties cause this micronutrient to be present in the vast majority of formulas intended… Continue reading Antioxidant, anti-wrinkle and tone unifier
The summer It is a time of year when temperatures rise considerably, so it is necessary to take a series of precautions around the ultraviolet sun rays. Also people with diabetes, since the heat increases the blood glucose levels in the body. In addition to adequately protecting ourselves from the sun to prevent skin… Continue reading The importance of extreme glycemic control in summer
The importance of vitamin D for the Health it goes beyond what we can imagine. To be as concise as possible, we will say that consuming vitamin D saves lives. That is, to have optimal levels of this micronutrient in the body will help prevent different diseases or health conditions. Vitamin D is a… Continue reading Vitamin D Consumption Saves Lives, Experts Say
The b12 vitamin It’s one of the micronutrients essential for Health of people, so it is essential to have a balanced and healthy diet with foods that contain this type of vitamins among their composition. While vitamin B12 is only found in food of animal origin. In this sense, vitamin B12 deficiency in the… Continue reading Alcohol’s ‘dangerous’ reaction to vitamin B12
A few days ago it was held in Spain the meeting ‘Vitamin D: Controversies and evidence 2021’. An event in which different health specialists from the country participated and spoke about the medical use of the vitamin D on Spain and especially for the prevention of osteoporosis. In this sense, the internist Francisco López… Continue reading Lack of vitamin D is a public health failure, experts say
People tend to be exposed to Sun for many hours at the time of summer, something that can be detrimental to the Health, to the point of leading to the appearance of skin cancer. While some micronutrients such as vitamin C wave Vitamin A they act as skin protectors. It is normal that during… Continue reading Does vitamin A reduce the risk of skin cancer in summer?
We do not discover anything new when we affirm that as we get older, skin ages, as does all of our organism. However, there are numerous ways (some of them natural), which help to maintain a young skin for much of our lives. Eat food with vitamin C help to. At present we observe… Continue reading Fruits rich in vitamin C for aging with healthy skin
The Gazpacho It is one of the treasures of the gastronomy Mediterranean. The ingredients of this dish originally from Andalusia provide important benefits to the Health and it is undoubtedly one of the most consumed dishes during the hot summer months. The vitamin C wave Vitamin A support your intake. The Andalusian gazpacho recipe… Continue reading Vitamin C and other benefits of taking gazpacho in summer | 3,997 | 1,832 | 8,511.079148 |
warc | 202143 | When you’re thinking about marketing your small business you want to be sure you are offering
transparency and accessibility.
Social media gives you as the business owner to
build trust that does not have to be manufactured. Yet it is vital for pretty much every industry.
But many small businesses struggle with the idea of marketing on social media.
Why?
You may be hesitant because you don’t see the value of spending time there. However
consumers now are expecting transparency. They want to be able to go on Instagram, find your page and scroll through your products and see what you and others are saying.
You don’t need to be on every single social media platform. But when you have a presence on the right social media platform, it’s a way for your target customers to connect with your brand. (see how it all ties together?)
There are so many creative ways to market on social media. Platforms such as Instagram can provide a cool ‘
behind the scenes’ look into your business – a first look at upcoming products. People can instantly engage with it. You can do live videos, you can do reels. Get a good grid going and start building up your brand. Instagram grid example
Always remember to put out content that will make an impact. This can be a challenge since people are getting bombarded with millions of ads each day. Put time and thought into
curating content.
Don’t have the mental capacity but have the budget? This would be a good time to think about hiring people that specialize in this field to do it for you.
One of the greatest benefits of being a small business is that you can run your company how you want.
You can see your visions come to life. With the right digital marketing strategy your journey as an entrepreneur can be a very long and fulfilling one. | 1,840 | 958 | 3,424.551148 |
warc | 202143 | On October 5th, the Burnett County Land Use & Info committee (LUIC) voted unanimously in support of updated rules for campgrounds and RV Parks in Burnett County.
The new rules would:
The proposal from the LUIC now goes to the full county board for approval later this month (Thursday, October 21st).
FOR IMMEDIATE RELEASE: BURNETT COUNTY LAND USE & INFORMATION COMMITTEE UNANIMOUSLY RECOMMENDS UPDATED RULES FOR CAMPGROUNDS AND RV PARKS
SIREN, WI – By a 6-0 vote at their October 5th meeting, the Burnett County Land Use and Information Committee passed a series of updated rules designed to reduce conflicts over future campground projects. The committee had spent nearly six months researching the issue and hearing testimony from a wide variety of stakeholders, experts and concerned citizens. This followed a succession of contentious committee meetings where the committee faced objections from hundreds of citizens opposed to these high-density developments in both residential areas and rural neighborhoods.
Preserve Burnett County, a citizen group formed to bring more focus to the issues high-density campgrounds pose, applauded the committee’s action. “Over 1,600 county residents and property owners voiced their concerns about the rampant growth of high-density campgrounds here over the last few years,” said Patrick Hansen, a spokesperson for the group. “Local citizens made it clear that they want uniform, sensible standards in siting, size and density of these so-called ‘campgrounds’, which are primarily RV and Park Model lots, with large patios, decks, and sheds. Once these ‘camping units’ are installed, they never move.”
600+ PBC supporters sent 5,000+ letters and emails to county supervisors asking for caps on numbers of campsites in a campground, an end to campgrounds in residential areas and a 14-day limit on length of stay for “temporary camping”. In the end, the committee voted to establish a new zoning district that will be directed at current and potential campground owners, with a minimum parcel size of 10 acres. They also voted to prohibit campgrounds in residential areas and to limit campsites to 25 units for “temporary camping” on agricultural and forest land. Campsites would be capped at 100 in the new zoning district. The new zoning district restores local control over County land use decisions, giving Supervisors discretion that was otherwise taken away under Wisconsin Act 67. As Vice-Chair Conroy said at the Tuesday hearing, "it will take the 900-pound gorilla off our backs."
“We didn’t get everything we’d hoped for,” said Hansen. At the same time, he lauded the committee members for their willingness to hear citizen concerns and input. “We thank the full committee, especially Chairman Bickford and the three members of the Campground Work Group – Supervisors Conroy, Paden, and Awe – for their hard work, their accessibility and their willingness to listen to all points of view.”
While acknowledging that the group didn’t get all their wishes, Hansen said he thinks the process of siting campgrounds in the county will be more orderly with an eye to preserving the unique qualities of our area that draw full-time residents and summer visitors in the first place. “Preserving the rural character of our county and protecting our waterways and open spaces from over-development has always been our primary aim. These changes are a step in that direction. We’re happy with the outcome, but also staying vigilant to see how any new rules play out.”
The changes are not a done deal. The full county board will hear the committee’s report and vote on the measures at their regular monthly meeting on October 21st.
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warc | 202143 | Contest details
High blood pressure is a condition that is both “silent” and “fatal.” According to medical professionals, hypertension is a silent disease since you may live with it for years without realizing it. High blood pressure is also thought to be deadly since complications from high blood pressure, such as aneurysms, strokes, and heart attacks may result in rapid death.
Furthermore, scientists estimate that millions of Americans have “undetected” hypertension, with many more at risk of acquiring the condition. While doctors suggest obtaining a thorough medical examination at least twice a year, many individuals cannot do so regularly.
What is Arteris Plus Dietary Formula?
John Mayers founded Philadelphia-based
Arteris Plus supplements. John claims to have always been a proponent of using herbal extracts to improve one’s health. As a consequence, John Mayers has devoted countless hours to studying natural plant-based blood pressure solutions. John eventually developed Arteris Plus, an excellent supplement that may combat hypertension regardless of age. Arteris Plus Dietary Supplement is a plant-based, safe, and adequate blood pressure medication made with natural components. According to John Mayers, the ingredients in Arteris Plus, such as Marshmallow, Passion Flower, Corydalis, California Poppy Seeds, and Prickly Pear, have been clinically proven to improve heart health. Official Website: Click Here
Each bottle of Arteris Plus includes 60 blood pressure support pills, enough to last you thirty days.
Arteris Plus Pills, according to John Mayers, may help you combat persistent high blood pressure and the adverse effects of prescription hypertension medications. Customers of Arteris Plus should be informed, however, that this product is not FDA-approved. What is Arteris Plus, and how does it work? Arteris Plus Reviews is one of those supplements that are immediately effective. It doesn’t need to be explained; it simply is. Arteris Plus has the potential to change how individuals control their high blood pressure. However, since everyone’s tolerance to various drugs varies, some people may not see any effects from the supplement. Even if this is the case, Arteris Plus has a reasonable probability of working on individuals like you and me. Arteris Plus is comprised of the following individuals: Enough soothing chemicals are provided to relieve some hormonal sensations. lowering blood sugar and cholesterol levels in our bodies Returning our blood pressure to normal levels after it has risen to dangerously high levels Enough soothing chemicals are provided to relieve some hormonal sensations: Arteris Plus Dietary Supplement Reviews has so many anxiety-relieving components that it will keep you calm all day. In certain instances, the ingredients in each Arteris Plus pill may help to alleviate stress and depression symptoms. However, It may also pump and excite you with serotonin, the happy hormone, to dull your pain and encourage you to do the activities you like while this is going on. lowering blood sugar and cholesterol levels in our bodies:
After that, several of Arteris Plus components help lower your blood glucose and cholesterol levels. The prickly pear and the antioxidants contained in the supplement, in general, are primarily responsible for this. Reduced blood sugar and cholesterol levels in the circulation make it simpler for blood to flow to where it’s required, reducing the strain on the arteries and decreasing the risk of high blood pressure in the long term.
Returning our blood pressure to normal levels after it has risen to dangerously high levels:
Our blood pressure should improve over time due to the two-pronged strategy of correcting our blood parameters and restoring proper hormone balance. You may live life to the fullest without worrying about having a stroke anytime soon if your blood pressure is under control.
Arteris Plus ingredients:
Arteris Plus contains the following five ingredients:
Passionflower Marshmallow Root Corydalis Lutea Prickly Pear California poppy seeds
All of the components in Arteris Plus are:
Safe:
John promises that a third source verifies all components. Furthermore, each Arteris Plus pill is made in an FDA-approved and GMP-certified facility in the United States.
Natural:
All fixings are from local farmers that let their plants develop organically without the use of chemicals, pesticides, or herbicides, according to the creator of It.
Effective:
Each Arteris Plus pill is said to have the proper dose, ensuring that customers get the correct dosage.
Non-addictive:
Arteris Plus is non-addictive since it contains no stimulants, and users will not experience withdrawal symptoms if they stop using it.
Scientifically proved:
According to John Mayer, all of the components are scientifically proven to help manage hypertension.
What are the benefits of Arteris Plus for lowering blood pressure?
According to the manufacturer of It, this combination includes components that enhance blood flow in your system by expanding blood vessels. Additionally, It boosts your system’s metabolism, allowing your heart to operate better by increasing energy levels.
Additionally, It contains substances that induce relaxation, thus reducing tension and anxiety. Arteris Plus, according to John Mayers, may lower bad cholesterol (LDL) and triglyceride levels, allowing for improved blood circulation by unblocking arteries. Finally, It helps burn fat deposits around the heart and other vital organs, boosting heart health.
What are the Arteris Plus side effects?
The possibility of Arteris Plus ingredient adverse effects is ruled out. There will be no adverse effects if the product is used according to the instructions. However, attempting to overdose on it (e.g., taking three or more pills per day) may result in life-threatening adverse effects that may negatively impact one’s overall health.
Overdosage of Arteris Plus may result in the following It adverse effects:
Hypotension Coordination problems Drowsiness stomach ache Excessive pleasure
To treat hypertension and decrease the chance of becoming hypertensive, health experts suggest adopting lifestyle changes. The following are some healthy lifestyle changes that may help you avoid hypertension:
Exercising:
Doctors suggest doing aerobic workouts for at least 20 minutes per day to assist with high blood pressure. Climbing stairs, cycling, walking, running, and swimming are all beneficial to your heart health.
Stress management:
Stress management is critical in the prevention of high blood pressure. Stress-relieving methods include long walks, warm baths, and yoga. Recreational drugs, cigarettes, high-calorie foods, and alcohol use are poor stress relievers since they increase the risk of hypertension.
Diet:
A well-balanced, nutrient-dense diet is essential for preventing hypertension.
Weight:
Excess weight wears down the heart because it can’t pump enough blood to all of the body’s components. Weight loss increases blood flow and expands blood vessels, allowing for improved blood circulation and lowering the risk of hypertension.
Summary:
To summarise, Arteris Plus is an anti-hypertension dietary supplement containing five relaxing, antioxidative components that help maintain healthy blood pressure. We can decrease our blood pressure and improve our blood health by relaxing our minds. It works for folks like you and me, as we can see. This product is highly recommended for individuals looking for a non-traditional yet effective way to reduce their blood pressure.
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no | 7,781 | 3,304 | 18,034.775424 |
warc | 202143 | Consumer electronic devices are gaining popularity because they provide sophisticated features that can be useful to people in their day to day lives. Certain of these products do not only provide entertainment, but also aid us in our work.
Electronic products have brought many comforts and ease in our lives. Electronic products that are popular today include televisions digital cameras, digital cameras and accessories including computers, DVD recorders and various other electronic devices for the home. As technology advances, we are also
newshunt360 evolving. Every so often there are new inventions and new products being made. The world that is consumer electronic technology is constantly experiencing some changes. A variety of new devices are appearing in the marketplace. The need for the latest technology is growing day by day.
Electronics and consumer electronics have become a significant aspect of the lives we lead that we can’t imagine a life without these devices. Technology is evolving at a an accelerated pace, which has led to the rise of a many electronic products. In the same way consumers must to be informed regarding the most current gadgets and technologies to ensure that they get the most benefit from these devices. The market for consumer electronics is growing rapidly and new devices are coming onto the market.
Innovating our lives, electronic gadgets have created a dependence on. Some of the most sought-after electronic products include gaming consoles as well as mobile phones, as well as music players. These premium devices are popular with consumers all over the world because they’re tools of entertainment , as well as useful gadgets.
The most well-known brands like Sony, LG, Samsung and Philips are coming out with the top products. Every six months, you will see an updated version of these gadgets. This means that the user begins feeling like his device is old. In addition to being used for daily use, they are also used to enhance our curiosity and enjoyment.
A well-known entertainment and a useful device is the mobile phone. Beyond just communication they permit users to utilize email, browse the internet, upload photos or listen to audio. You can download music via the web or to share your files with your friends, you can do so via your mobile.
With the latest electronic gadgets that are available, you can perform many tasks with ease and comfort. Explore the internet sites and you will find a wide range of consumer electronic gadgets that include a variety of brands. The trend of shopping comparison is becoming more popular. Comparing products on the basis of their characteristics is getting more simple. Shopping for electronic gadgets online offers the opportunity to search for many different products on the internet under one roof. It is easy to find the specifications of their products or search for the latest products on the market. Find out as much as you can and then take the time to evaluate the various products and costs. It is not necessary to go to every retailer.
Digital cameras as well as accessories are light and compact, allowing us to preserve our memories. The rapidly developing world is changing rapidly technologies and lifestyles. The demand for the latest electronic gadgets has been growing rapidly. New brands are providing different entertainment and communication devices for consumers. | 3,411 | 1,537 | 7,525.50488 |
warc | 202143 | Within a food system perspective, IFSI works to address food insecurity through a commitment to innovative research, empowering outreach and capacity building, and objective evaluation.
Affiliated Programs IFSI serves as a hub to coordinate cooperation among four relevant programs at the University of Illinois towards a common goal of food security. These programs include: Soybean Innovation Lab (SIL), ADM Institute for the Prevention of Postharvest Loss, AgReach, and Appopriate Scale Mechanization Consortium (ASMC). Selected Projects IFSI helps support and promote the activities of its affiliated faculty who are working to innovate for food security, empower for food security, and evaluate for food security.
The International Food Security at Illinois program launched the Initiative on Big Data, Food Security and the Environment in April 2016 with the goal of bringing together researchers and stakeholders to use big data tools to reduce world hunger while improving the stewardship of natural resources. | 1,022 | 585 | 1,778.454701 |
warc | 202143 | document Assessment of Dermal Absorption of Aluminum from a Representative Antiperspirant Formulation Using a 26 Al Microtracer Approachde Ligt, R. (author), van Duijn, E. (author), Grossouw, D. (author), Bosgra, S. (author), Burggraaf, J. (author), Windhorst, A. (author), Peeters, P.A.M. (author), van der Luijt, G.A. (author), Alexander-White, C. (author), Vaes, W.H.J. (author)A clinical pharmacokinetic study was performed in 12 healthy women to evaluate systemic exposure to aluminum following topical application of a representative antiperspirant formulation under real-life use conditions. A simple roll-on formulation containing an extremely rare isotope of aluminum (26 Al) chlorohydrate (ACH) was prepared to... article 2018 document Comparing high altitude treatment with current best care in Dutch children with moderate to severe atopic dermatitis (and asthma): Study protocol for a pragmatic randomized controlled trial (DAVOS trial)Fieten, K.B. (author), Zijlstra, W.T. (author), van Os-Medendorp, H. (author), Meijer, Y. (author), Venema, M.U. (author), Rijssenbeek-Nouwens, L. (author), l' Hoir, M.P. (author), Bruijnzeel-Koomen, C.A. (author), Pasmans, S.G.M.A. (author)Background: About 10 to 20% of children in West European countries have atopic dermatitis (AD), often as part of the atopic syndrome. The full atopic syndrome also consists of allergic asthma, allergic rhinitis and food allergy. Treatment approaches for atopic dermatitis and asthma include intermittent anti-inflammatory therapy with... article 2014 | 1,542 | 830 | 2,861.060241 |
warc | 202143 | Abstract
From the outset of deregulation and privatisation of UK electricity markets, the desired extent of vertical integration has been debated. Concerns over the dominance of the “Big Six” majors and whether consumers were receiving a fair deal, led the new Government of 2010 to promote the entry of new retail supply firms without generation assets. Increasing consumer choice and facilitating supplier switching were seen as counter-weights to the dominance of the vertically integrated majors. Through various policies favouring new, assetless suppliers, the domestic retail electricity market in the UK has become less concentrated offering more choice to consumers. But the process of reducing market concentration has had setbacks: many new retail suppliers went bankrupt and service quality has been mixed. To address possible short-comings, the Regulator in mid-2019 introduced stricter requirements for a retail supply license but are they sufficient? Combining theory with empirical analysis, it is argued that enhanced requirements are unlikely to be sufficient to ensure the success of these new firms because assetless retailers face competitive disadvantages under the current market structure. Before debating the role and benefits of such firms, their economic viability should be assessed.
Original language English Journal Economic Affairs Volume 41 Issue number 3 Publication status Published - 15 Oct 2021 Keywords Retail Electricity Risk Management Market Efficiency | 1,505 | 829 | 2,706.821472 |
warc | 202143 | Abstract
Background: Consumption of snacks might contribute to the obesity epidemic. It is not clear how the moment of consumption and energy density of snacks can influence the compensatory response to consumption of snacks in the long term. Objective: To investigate the effects of snack consumption for 8 weeks on changes in body weight, emphasizing on moment of consumption and energy density. Design: In total, 16 men and 66 women (mean age 21.9 years (s.d. 0.3 year), mean body mass index 20.7 kg m-2 (s.d. 0.2 kg m-2)) were randomly assigned to one of four parallel groups in a 2 2 design: snacks consumed with or between meals and snacks having a low (12 kJ g-1) energy density. For 8 weeks, subjects consumed mandatory snacks that provided 25% of energy requirements on each day. Body weight, body composition, physical activity level (PAL) and energy intake were measured in week 1 and week 8. Results: There were no differences in changes in body weight between the four groups. Moment of consumption (P=0.7), energy density (P=0.8) and interaction (P=0.09) did not influence body weight. Similarly, there were no differences in changes in body composition, PAL and energy intake between the four groups. Conclusions: Body weight after 8 weeks of snack consumption was not affected by moment of consumption and energy density of snacks. This finding suggests that consuming snacks that are high or low in energy density does not necessarily contribute to weight gain. Healthy, nonobese young adults may be able to maintain a normal body weight through an accurate compensation for the consumption of snacks
Keywords portion size food-intake meal frequency density men women metabolism balance satiety obesity | 1,723 | 843 | 3,513.448399 |
warc | 202143 | Incandescent, CFL or LED? Choosing a bulb would appear to be a straight forward choice. Incandescent bulbs are slowly being withdrawn as they are better at making heat than light! However, we are very used to the light that they …
Tag: CFL
Lighting is a difficult area to understand – there is a whole industry built around designing lighting layouts, however there are some basics that people should understand when looking into choosing lighting for their homes. With incandescent lighting slowly being … | 525 | 328 | 809.908537 |
warc | 202143 | A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2017; you can also visit the original URL.The file type is
application/pdf.
The economics of beauty has been an emerging issue recently. Report revealed handsome and beautiful people earn more than ordinary. This research investigated the correlation between personal traits and beauty as well as happiness. We aim to discover (1) what are the personal traits and the degree of beauty that influence happiness and (2) what are the personal traits and degree of happiness that influence beauty. We used synthesized data mining techniques (clustering and classification) todoi:10.5296/ijhrs.v3i4.4551 fatcat:g3gzzzsnife2tngo6uanitdcw4 | 758 | 453 | 1,261.660044 |
warc | 202143 | A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2010; you can also visit the original URL.The file type is
application/pdf.
Trust reciprocity, a special form of link reciprocity, exists in many networks of trust among users. In this paper, we seek to determine the extent to which reciprocity exists in a trust network and develop quantitative models for measuring reciprocity and reciprocity related behaviors. We identify several reciprocity behaviors and their respective measures. These behavior measures can be employed for predicting if a trustee will return trust to her trustor given that the latter initiates adoi:10.1137/1.9781611972801.7 dblp:conf/sdm/NguyenLTJS10 fatcat:awseiazinrhc7moi2h4ekh7pau | 787 | 479 | 1,286.473904 |
warc | 202143 | A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2020; you can also visit the original URL.The file type is
application/pdf.
ABSTRACTNew global history studies have provided theoretical models related to different paths of economic growth and consumer behaviour between East Asia (mainly China and Japan) and Europe during the period of the first industrialisation. However, more research challenging the Eurocentric views of the origins of globalisation is needed. In this article, I examine the exchanges of Chinese silks and porcelains and European wines and liquors for American silver through the Swedish Grill Company.doi:10.1017/s0212610919000235 fatcat:iypqfexpljconodrh6i2sa5gym | 764 | 512 | 1,134.0625 |
warc | 202143 | A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2017; you can also visit the original URL.The file type is
application/pdf.
Epstein-Barr virus (EBV) infection has been implicated in the aetiopathogenic mechanisms of several neoplastic and non-neoplastic disorders. Although the precise mechanisms of the tumourigenic actions of EBV have not yet been fully elucidated, this virus has been strongly linked to subtypes of Hodgkin's and non-Hodgkin's lymphomas (especially Burkitt's lymphoma), HIV/AIDS lymphomas, nasopharyngeal carcinoma and gastric carcinoma, among several others. The fact that persistent infections occurdoi:10.2174/1874279301004010101 fatcat:7sz3gylfibcvhh3ptjvasezzje | 764 | 481 | 1,207.151767 |
warc | 202143 | A systematic assessment of the association between frequently prescribed medicines and the risk of common cancers: a series of nested case-control studies 2021 BMC Medicine
Background Studies systematically screening medications have successfully identified prescription medicines associated with cancer risk. However, adjustment for confounding factors in these studies has been limited. We therefore investigated the association between frequently prescribed medicines and the risk of common cancers adjusting for a range of confounders. Methods A series of nested case-control studies were undertaken using the Primary Care Clinical Informatics Unit Research (PCCIUR) doi:10.1186/s12916-020-01891-5 pmid:33494748 fatcat:nsj3dzmizvdcxncmcos6q3jaei
more » ... Research (PCCIUR) database containing general practice (GP) records from Scotland. Cancer cases at 22 cancer sites, diagnosed between 1999 and 2011, were identified from GP records and matched with up to five controls (based on age, gender, GP practice and date of registration). Odds ratios (OR) and 95% confidence intervals (CI) comparing any versus no prescriptions for each of the most commonly prescribed medicines, identified from prescription records, were calculated using conditional logistic regression, adjusting for comorbidities. Additional analyses adjusted for smoking use. An association was considered a signal based upon the magnitude of its adjusted OR, p-value and evidence of an exposure-response relationship. Supplementary analyses were undertaken comparing 6 or more prescriptions versus less than 6 for each medicine. Results Overall, 62,109 cases and 276,580 controls were included in the analyses and a total of 5622 medication-cancer associations were studied across the 22 cancer sites. After adjusting for comorbidities 2060 medicine-cancer associations for any prescription had adjusted ORs greater than 1.25 (or less than 0.8), 214 had a corresponding p-value less than or equal to 0.01 and 118 had evidence of an exposure-dose relationship hence meeting the criteria for a signal. Seventy-seven signals were identified after additionally adjusting for smoking. Based upon an exposure of 6 or more prescriptions, there were 118 signals after adjusting for comorbidities and 82 after additionally adjusting for smoking. Conclusions In this study a number of novel associations between medicine and cancer were identified which require further clinical and epidemiological investigation. The majority of medicines were not associated with an altered cancer risk and many identified signals reflected known associations between medicine and cancer. | 2,647 | 1,225 | 5,700.233469 |
warc | 202143 | A balanced scorecard for measuring the impact of industry–university collaboration 2011 Production planning & control (Print)
The Balanced Scorecard (BSC) can be considered as a strategic measurement tool. Since its first publication by Norton and Kaplan in the early 1990's, many companies have applied it to measure four key aspects of their organisations' performance: Financial, Customer, Internal Business Process, Learning and Growth. Although it is widely used in the business arena, this original BSC was not developed to assess the impact of collaborative research projects under an open innovation strategy, where doi:10.1080/09537287.2010.536626 fatcat:4dbpir4mjfa2dhnlgba4yu6bou
more » ... n strategy, where the outputs of research and development (R&D) developed by collaborative projects undertaken by industry and universities should be measured in a different way. Therefore, this paper will propose a Scorecard to measure the outcomes of collaborative research. It is important to recall that this scorecard has been developed during a collaborative research project by CEMEX Research Group AG (Switzerland) and Cranfield University (UK). During such project, a survey was developed to carry out eleven face-to-face interviews in a sample of ten companies in UK, where it was confirmed that a collaborative balanced scorecard (CBSC) is a very useful tool to measure, track and improve the impact of conducting collaborative projects with universities. It should also be noted that this paper is an extended version of the one presented at the PRO-VE'09. | 1,584 | 858 | 2,898.461538 |
warc | 202143 | Accuracy of trained rural ophthalmologists versus non-medical image graders in the diagnosis of diabetic retinopathy in rural China 2018 British Journal of Ophthalmology
Telephone: +44 (0)28 9097 8929 Fax: +44 (0)28 9097 Word count-3,890 Precis Non-medical personnel in rural China graded images obtained by nurses on patients with high cataract prevalence, meeting standards of the United Kingdom's National Diabetic Eye Screening Programme, and surpassing the performance of trained local ophthalmologists. 4 Abstract Background/aims To determine the diagnostic accuracy of trained rural ophthalmologists and non-medical image graders in the assessment of diabetic doi:10.1136/bjophthalmol-2018-312440 pmid:29973366 fatcat:o7rsjdbyajac3idp4myy4kwobu
more » ... ment of diabetic retinopathy (DR) in rural China. Methods Consecutive patients with diabetes mellitus were examined from January 2014 to December 2015 at ten county-level facilities in rural Southern China. Trained rural ophthalmologists performed a complete eye examination, recording diagnoses using the United Kingdom National Diabetic Eye Screening Programme (NDESP) classification system. Two field, mydriatic, 45° digital photographs were made by nurses using NDESP protocols, and graded by trained graders with no medical background using the NDESP system. A fellowshiptrained retina specialist graded all images in masked fashion and served as reference standard. Results Altogether, 375 participants (mean age 60 +/-10 years, 48% men) were examined and 1277 images graded. Grader sensitivity (0ꞏ82-0ꞏ94 (median 0ꞏ88)) and specificity (0ꞏ91-0ꞏ99 (median 0ꞏ98)), reached or exceeded NDESP standards (sensitivity 80%, specificity 95%) in all domains except specificity detecting any DR. Rural ophthalmologists' sensitivity was 0ꞏ65-0ꞏ95 (median 0ꞏ66) and specificity 0ꞏ59-0ꞏ95 (median 0ꞏ91). There was strong agreement between graders and the reference standard (kappa=0ꞏ84-0ꞏ87, P<0ꞏ001) and weak-moderate agreement between rural doctors and the reference (kappa= 0ꞏ48-0ꞏ64, P<0ꞏ001). 5 Conclusion This is the first study of diagnostic accuracy in DR grading among non-medical graders or ophthalmologists in LMICs. Non-medical graders can achieve high levels of accuracy, whereas accuracy of trained rural ophthalmologists is not optimal. In rural China, 81% of patients with DM do not receive an annual eye examination,[8] as recommended by Chinese guidelines adopted from the American Academy of Ophthalmology,[9] and 69% have never received an eye examination, [8] . This is largely due to uneven distribution of providers, with 80% of Chinese ophthalmologists located in urban areas, [10] . Therefore, it is necessary to explore alternate DR screening approaches in order to reduce demands on the small cadre of rural Chinese ophthalmologists, so capacity is freed for seeing those requiring treatment. To achieve this, critical evaluation of the accuracy of different models of rural DR screening is required. The aim of the present study is to compare the accuracy of two methods of DR screening: trained rural doctors performing complete eye examinations with grading of DR severity, and trained non-medical graders remotely examining retinal photographs taken by ophthalmic nurses. METHODS Study Setting This study was undertaken in Guangdong Province, Southern China. Data were collected from the Comprehensive Rural Eye Service Training (CREST) programme, an ongoing, five year collaboration | 3,575 | 1,673 | 7,417.109982 |
warc | 202143 | Recent Advances in Time-Resolved NIR Spectroscopy for Nondestructive Assessment of Fruit Quality 2015 Chemical Engineering Transactions
Non-destructive monitoring of food internal attributes by near infrared spectroscopy (NIRS) is typically performed by the continuous wave (CW) technique, where steady state light sources (e.g. lamp or LED with constant intensity in time) and photodetectors (e.g. photodiode or charge coupled device camera) are used to measure light attenuation. Indeed light scattering can largely affect light attenuation resulting in the need of calibration for each new batch of samples. To tackle this effect doi:10.3303/CET1544008 doaj:112e7270bc7a42b69eec5533d31f267c fatcat:y34efehoxbf6bjewrrlxda7flm
more » ... ckle this effect time-resolved NIRS (TRS) has been proposed to improve the classical CW approach to NIRS. The main feature of TRS is its ability to retrieve information on photon path-length in a diffusive medium (generally much larger than the geometrical distance between source and detector). The use of TRS in combination with proper physical models for photon migration allows for the complete optical characterisation with the simultaneous non-destructive measurement of the optical properties (absorption and scattering) of a diffusive medium. This can be of special interest for most fruits and vegetables as well as for other foods (e.g. meat, fish, and cheese), because information derived by TRS refers to the internal properties of the medium, and is not so much affected by surface features as is the case for CW spectroscopy. In the past TRS measurements were possible only with complex laboratory instrumentation consisting of picosecond pulsed lasers, water cooled photomultiplier tubes, and electronic chain for time- correlated single photon counting. In this work we present the recent advances in TRS technology (laser, detectors and acquisition electronics) that allow the design of portable instrumentation for use in the pre- harvest (i.e. in the field) and post-harvest. | 2,042 | 1,109 | 3,743.359784 |
warc | 202143 | A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2020; you can also visit the original URL.The file type is
application/pdf.
In qualitative research, context is essential in order to observe and understand the phenomena of interest in a more holistic way. Emphasizing context in knowledge management (KM) initiatives helps managers choose the most suitable way to implement KM in accordance with their business strategies. This paper integrates the concepts of context, Earl's (2001) seven schools of knowledge management (KM), a reverse data-information-knowledge hierarchy, and knowledge reusability. By considering twodoi:10.1109/icdim.2010.5664662 dblp:conf/icdim/HsiehLH10 fatcat:jcrn4a22anecfkpu4nzi3upf6m | 788 | 509 | 1,213.736739 |
warc | 202143 | Effects of color filters and anti-reflective coating on contrast sensitivity under glare condition 2019 Journal of Research in Clinical Medicine
Since light scattering has a great impact on visual performances, this study was conducted to compare the effects of color filters and anti-reflective coating on contrast sensitivity (CS) in normal people under glare condition. Methods: This semi-experimental study was conducted on 40 medical students (aged 19-25 years). Ophthalmologic tests including visual acuity and refractive error measurement, biomicroscopy, fundoscopy, and CS assessment were conducted for all participants. CS was doi:10.34172/jrcm.2020.028 fatcat:ayza6mf2xzb4de75yqy63ugghq
more » ... ts. CS was determined using Pelli-Robson chart at a distance of one meter. To measure the effect of glare on CS, we used an additional lighting source (60 W tungsten filament incandescent lamp) in the patient's visual field. Thus, at an intensity of 2000 lux, the light source was placed at a distance of 18.5 cm from the patient's eye in a way that it was 10 degrees above the subject's visual axis. Monocular CS measurements were performed with and without glare. Monocular CS was evaluated again under glare conditions with the yellow and pink filters, with the transmission rate of 85%, and anti-reflective coating. Results: The mean log CS of subjects under glare (1.48 ± 0.09) was lower than that in the absence of glare (1.71 ± 0.09) (<0.001); moreover, repeated measures ANOVA showed the yellow filter (1.48 ± 0.10), pink filter (1.47 ± 0.10), and anti-reflective coating (1.47 ± 0.09) had no significant impact on improving visual performance under glare condition (P = 0.471). Conclusion: Colored filters and anti-reflective coatings are not effective in enhancing the vision of young normal individuals under glare conditions and at low spatial frequencies. | 1,910 | 970 | 3,693.979381 |
warc | 202143 | Amino-Terminal Sequences of Some Escherichia coli 30S Ribosomal Proteins and Functionally Corresponding Bacillus stearothermophilus Ribosomal Proteins1 1974 Journal of Bacteriology
Amino-terminal sequences of five purified Escherichia coli 30S ribosomal proteins (S4, S9, S10, S16, and S20) were compared with those of their functionally corresponding Bacillus stearothermophilus ribosomal proteins identified previously by the reconstitution technique. An automatic Edman degradation method was used for sequence determinations. The sequence of the first 30 residues is presented, except that only the first 25 residues are shown for the S20 pair. Substantial (40 to 70%) doi:10.1128/jb.118.1.180-186.1974 fatcat:fifkx4abibby3ir3me5a7guapu
more » ... (40 to 70%) sequence homologies have been observed in every case. The results show that the pairs of functionally equivalent proteins, previously identified by the reconstitution technique, are also chemically related. Thus, the present chemical studies give further support for the previous conclusion that two ribosomes with different properties, 30S subunits from E. coli and B. stearothermophilus, have the same fundamental structural organization. Earlier experiments from this laboratory demonstrated that functionally active 30S ribosomal subunits can be reconstituted from the 16S ribosomal ribonucleic acid (rRNA) of one species of bacteria and that the ribosomal proteins (r-proteins) can be reconstituted from a distantly related species (18). It has been suggested that the specific part of r-proteins interacting with the rRNA may have a structural feature in common with "corresponding proteins" from different bacterial species. In extending this work further, we have recently performed experiments to determine whether r-proteins from distantly'related bacterial species can be shown to be functionally equivalent on a one-to-one basis (11). For this purpose, we fractionated 30S r-proteins from Bacillus stearothermophilus (B proteins) and looked for functional correspondence between these proteins and Escherichia coli 30S r-proteins (E proteins) by using the reconstitution technique. The properties of the ribosomes from these two organisms are different in several respects, as discussed in previous papers (11, 18) . There are distinct chemical differences between the 16S RNAs of the two species (18, 21 and papers cited therein). Moreover, the proteins from 30S subunits differ with respect to their column chro-I Paper no. 1707 of the Laboratory of Genetics, University of Wisconsin, Madison, Wis. 53706. matographic (11) or gel electrophoretic patterns (1, 18, 26) , their ability to confer heat resistance upon the ribosomal subunits (9, 18, 20) , and their immunochemical properties (29). In addition, it is known that B. stearothermophilus 30S subunits cannot translate the coat protein and the replicase cistrons of RNA messenger from f2 and related RNA phages, whereas E. coli 30S subunits can (15). However, we have found that most, if not all, of the E proteins have functionally equivalent counterparts among B proteins, supporting the conclusion that the fundamental structural organization of ribosomes is the same throughout prokaryotic organisms (11). Complete interchangeability between E proteins and B proteins in the 30S reconstitution was somewhat surprising in view of the known differences between the ribosomal proteins of the two species described above, and especially surprising in view of the results of the immunochemical studies which showed very weak crossreaction between E and B ribosomal proteins (29). In addition, our previous conclusion on the conservation of ribosome structure, as well as r-proteins, depended for the most part on the functional assay of proteins by the reconstitution technique (11). Since we cannot completely exclude fortuitous stimulation of activity of protein-deficient reconstituted "30S" particles by some unrelated proteins, rigorous proof of 180 on May 7, 2020 by guest | 4,024 | 1,787 | 9,032.044768 |
warc | 202143 | A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2018; you can also visit the original URL.The file type is
application/pdf.
2000 Microscopy Today
The semiconductor industry is committed to introducing copper interconnects in place of aluminum for the latest generation of semiconductor devices. With its greater current carrying capacity, the use of copper should enable further reductions in device geometry, power consumption and heat generation, and lead to higher performance and longer battery life in portable devices.Grain orientations, crystal log raphic 'texture' trends and boundary types are crucial in determining properties such asdoi:10.1017/s1551929500052834 fatcat:o52xcqqmzfcmpous7su7d36vaa | 786 | 508 | 1,208.397638 |
warc | 202143 | CEACAM1 (CD66a) Promotes Human Monocyte Survival via a Phosphatidylinositol 3-Kinase- and AKT-dependent Pathway 2006 Journal of Biological Chemistry
CEACAM1 (also known as CD66a) is a transmembrane glycoprotein that mediates homophilic intercellular interactions that influence cellular growth, immune cell activation, and tissue morphogenesis. Various studies have suggested a link between CEACAM1 and cellular apoptosis, including a recent demonstration that ERK1/2 signaling is triggered downstream of CEACAM1. In this study, we reveal that CEACAM1-long binding confers survival signals to human peripheral blood mononuclear cells. doi:10.1074/jbc.m608864200 pmid:17071610 fatcat:gkveld4aszcptkoyq6yffhh7yy
more » ... ells. CEACAM-specific antibodies effectively protected peripheral blood mononuclear cells from apoptosis, with this effect being particularly dramatic for primary monocytes that undergo spontaneous apoptosis during in vitro culture. This protective effect was reiterated when using soluble CEACAM1, which binds to cell-surface CEACAM1 via homophilic interactions. Monocyte survival correlated with a CEACAM1-dependent up-regulation of the cellular inhibitor of apoptosis Bcl-2 and the abrogation of caspase-3 activation. CEACAM1 binding triggered a phosphatidylinositol 3-kinase-dependent activation of the protein kinase Akt without influencing the activity of extracellular signal-related kinase ERK, whereas the phosphatidylinositol 3-kinase-specific inhibitor LY294002 effectively blocked the protective effect of CEACAM1. Together, this work indicates that CEACAM1 confers a phosphatidylinositol 3-kinase-and Akt-dependent survival signal that inhibits mitochondrion-dependent apoptosis of monocytes. By controlling both ERK/MEK and PI3K/Akt pathways, CEACAM1 functions as a key regulator of contact-dependent control of cell survival, differentiation, and growth. Recent evidence suggests that the effect of CEACAM1 on immune cell function depends upon the isoform expressed. Differential splicing of CEACAM1 transcript generates either a long (73 amino acids) cytoplasmic domain-containing CEACAM1-L, which contains two immunoreceptor tyrosinebased inhibitory motifs (ITIMs) 3 that inhibit cellular growth | 2,242 | 1,124 | 4,454.080071 |
warc | 202143 | Abstract
The year 2008 marked the 11th anniversary of Hong Kong's return from the UK to the People's Republic of China. In this decade, the Hong Kong Special Administrative Region Government has repeatedly emphasised the importance of the development of national identity and patriotism in school education, and has at the same time introduced diverse cultural values into the school curriculum. This article explores the dynamics and complexity of the relationships between the state, globalisation and nationalism in Hong Kong that are re-shaping music education in response to contemporary socio-political changes. It argues that Hong Kong school music education has made a gradual cultural shift towards globalism and nationalism, and away from the Westernism that has dominated Hong Kong music education since before the change of sovereignty on 1 July 1997. The article concludes with a discussion of how music education might juggle two pairs of relationships in the curriculum: between global and national cultures; and between the education of cultural values and nationalism in Chinese music. There is pressure to rethink teacher education in terms of the need to be aware of the socio-political environment in which it operates, and within which it makes music education socially relevant.
Scopus Subject Areas Education Music User-Defined Keywords globalisation Hong Kong music education nationalism | 1,415 | 714 | 2,796.309524 |
warc | 202143 | Chemistry Salt doesn't actually melt ice, but here's how it makes freezing streets safer
The common belief that salt is put on streets to melt ice isn’t true, but other properties of salt make it a useful material when roads are freezing
Color changing ink turns everyday clothes into smart clothes which can sense chemicals and other information
New color changing ink technology could aid in health monitoring – through the clothes people wear daily
Farming on Mars will be harder than your favorite sci-fi movie makes it seem
The different soil and and lack of an atmosphere on Mars will make growing and harvesting crops more difficult than it is on Earth, despite how easy it seems in movies based on the red planet.
Researchers have developed a color-changing film inspired by Chameleons
The new color-changing film changes color in response to stretching, pressure, or humidity
A newer, safer way to train dogs to detect explosives and narcotics - K9 Chemistry
With new developments in the implementation of chemistry in technology, canine trainers will no longer have to expose dogs to dangerous materials to train them.
LEGOs can survive in the ocean for over 1,000 years
According to new research, a LEGO brick can survive in the ocean for as many as 1,300 years. | 1,296 | 720 | 2,291.4 |
warc | 202143 | Whether you are below to help make important, long-lasting relationships or here to experience some brief jokes, everything you claim and does points. We’d like anyone to experience a bit […]
Islamic money is about how corporations and people elevate cash prior to Sharia, or Islamic guidelines
Islamic loans concerns how ventures and folks improve capital as outlined by Sharia, or Islamic legislation. Aside from that it is the kinds investment which can be allowable under this form of law. Islamic loans is visible as an exceptional kind socially accountable finances. This subbranch of finance are a burgeoning field. In this post, we offer a synopsis to offer basic information and serve as the cornerstone for even more research.
The picture as a whole of Islamic Financial
Although Islamic financial set about inside the 7th century, it has been formalized progressively considering that the latter 1960s. This process would be motivated by way of the tremendous petroleum riches that supported renewed interest in and need for Sharia-compliant services rehearse.
Early Islamic caliphates experienced better-developed sector economic climates versus countries of Western European countries through the dark ages.
The notion of possibility writing is definitely central to Islamic financial and loans. It is very important comprehend the function of risk-sharing in raising funds. Simultaneously, Islamic finances requires the elimination of riba (usury) and gharar (ambiguity or lies).
Islamic rule perspective financing with interest girlsdateforfree reviews payments as a relationship that prefers the financial institution, that costs curiosity inside the borrower’s investment. Islamic laws looks at revenue as a measuring application for advantages instead a valuable asset in itself. As a result, it takes that certain really should not be capable to get earnings from dollars alone. Attention is deemed riba, and these types of rehearse try proscribed under Islamic rule. Actually haram, this means forbidden, because it’s thought about usurious and exploitative. In contrast, Islamic deposit is present to help the socio-economic desired goals of an Islamic area.
Correctly, Sharia-compliant economic (halal, meaning authorized) comprises bank when the loan company offers in the profit and loss on the venture it underwrites. Of identical benefit may be the concept of gharar. In a financial framework, gharar is the ambiguity and deception that can come from the purchase of objects whoever presence is actually uncertain. Types of gharar might types of insurance. Which may range from the purchase of costs to cover against whatever may or may not take place. Types accustomed hedge against conceivable results is another kind of gharar.
The resources financing of providers happens to be permissible, if those enterprises aren’t engaged in restricted firms. Prohibited tasks integrate making beer, playing, and creating porn material.
Practical Loan Plans
A short history of allowable loan plans usually experienced in Islamic money emerged below.
Profit-and-loss Submitting Commitment (Mudarabah)
The Islamic lender swimming pools traders’ funds and assumes a show from the earnings and losings. This procedure is actually decideded upon with all the depositors. Precisely what does the bank purchase? A team of mutual funds processed for Sharia agreement keeps emerged. The air filtration system parses company harmony sheets to figure out whether any sources of revenues into the group are actually banned. Employers retaining excessive debt or engaged in forbidden outlines of company include excluded. Besides actively managed a mutual investment fund, inactive finances can be found besides. Simply dependent on this type of indexes as the Dow Jones Islamic market place Index while the FTSE international Islamic directory.
Decreasing Balances Joint Resources
Decreasing stability provided assets calls for the bank in addition to the broker to get house together. It really is frequently used to finance your dream house acquisition. The lender steadily transfers their collateral inside the house to your person resident, whose transfers constitute any person’s money.
Rent to have
This plan is similar to the decreasing balance one expressed above, except the financial institution puts all the way up more, if not all, associated with the money for quarters and consents selling your home on the inevitable homeowner at the conclusion of a fixed expression. A part of every transaction runs toward the lease along with equilibrium toward your home’s purchase price. | 4,655 | 2,277 | 9,395.862978 |
warc | 202143 | Vice President of Solution at Visual Lease .
In a 2020 IDC survey, 42% of know-how choice makers reported that their companies prepared to commit in technologies to near the electronic transformation hole. We expect that amount has because risen.
Organizations spend in technology for quite a few good reasons: to streamline important processes, to keep related and to locate and sustain a competitive edge. What it will come down to is that a company’s tech stack is a key element of its advancement system.
I lately wrote an report about how to successfully establish and employ the suitable option to accommodate your modifying lease portfolio. No matter of which method you are now searching around for, you just cannot just select the “latest and greatest” technological innovation. You have to commit in the ideal technological innovation that will help your business enterprise right now and in the long run.
So, ahead of you enter into a new settlement with a resolution supplier, do your due diligence and acquire stock of what you presently have in spot. Think about possible answers as it relates to enterprise influence and strategic alignment — the intention is to locate a little something that drives both of those, and spend in it. Here are the concerns to question oneself together the way:
Are we continue to working with this?
Assessment each system that you at present have in place and make certain that it is staying applied — and at what ability. You are going to be astonished to come across that there could possibly be an possibility to go away from a distinct remedy (relying on your deal conditions) or make use of a little something in a way you didn’t previously know that you could. Possibly end result could have an impact on your conditions in deciding upon a new method. Implementing technological know-how that can help to preserve or exchange present procedures can have a high small business effects but falls on the decrease close of the spectrum when it will come to strategic alignment. So, this should really be just one of the points that a new remedy accomplishes, but it really should not be the sole matter that it provides to the table.
What do we like?
Create a “pros” record based mostly on your existing tech stack. For case in point, perhaps you actually adore the purchaser service working experience that a specific seller provides you. Or, probably your group enormously benefited from yet another vendor’s effortless-to-use interface. These are two things you really should include to the really best of your “must-have” listing. Obtaining these standards at the completely ready will make for uncomplicated discussions with opportunity suppliers and ensure that your new option will meet up with the requires of the team(s) who will be utilizing it. If you select technology that will drive rapid adoption (and success), you’re actively investing in your enterprise, which furthers strategic alignment and business effect.
What do we dislike?
Conversely, make a “cons” listing based mostly on your present tech stack or present-day procedures. Probably one of your present sellers will take without end to roll out products updates or does a bad occupation of speaking new product features. Or — and this is a huge one when it arrives to applying a lease optimization answer — you realize that your handbook approach of monitoring lease details by using Excel spreadsheets demands much too substantially time, threatens knowledge accuracy and is a surefire way to make critical faults that have an effect on your reporting.
Will it seamlessly integrate with other answers we like/prioritize?
A strong tech stack is a single that functions collectively, and in a lot of scenarios, your new alternative will have to have to simply plug into your current systems. Prioritize your wished-for integration abilities. When it comes to applying a lease optimization remedy, it is important that it can link to ERP programs to give people with a comprehensive image of their lease information. If your new technological innovation can’t provide you with meaningful information, it is substantially fewer beneficial to you and your organization.
In one more around the globe IDC survey, 70% of corporations claimed they started a new digital transformation initiative in 2020. Odds are that the strain to develop your organization’s electronic transformation attempts has amplified because the onset of Covid-19. But fairly than rush to employ new technological innovation, you are going to advantage from taking the time to understand what you have in spot.
With this awareness, you are going to confidently know how your upcoming expenditure will complement your present devices, accommodate your know-how roadmap and assist your organization well into the long term. A worthy financial commitment will push business effect and strategic alignment — and you shouldn’t settle for nearly anything significantly less. | 5,077 | 2,379 | 10,587.220261 |
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So, the next time you hit your gym, causes it to be a denote do some squats. I am aware it testosterone boost is not easy to undertake squats then they can a person sore thighs initially having said that can do wonders for any libido and testosterone heights.
Most of this time, oral sex is described as safe copulation. Why? Because the associated with protective materials like condoms is highly promoted this kind of kind of intimacy. But again there are many things to be thought of in using these protective devices.
Different angles. Over time, a few great missionary position can become really boring in bed and change anything offer you any other type of government. Get you your man to browse through different sites or books so you’re able both locate a position that may work inside your favor. Remember, you don’t always want to keep it to one position per night one or other. Feel free to throw many positions in the mix and continue your man on his toes.
Have better sex by adding a little sexy get hold of your relationship. Your automatically react to spoken words especially many of us hear many of our names. Mastering the art of dirty talk is not as hard perhaps you might think. You can consider the waters before you will get on the bedroom particularly if you have already followed step number four. Based on your partner’s text responses, you likely has a beneficial idea of just how long you can be once earning money the master bed room. Verbalize what you’re feeling and you are definate to excite your partner.
Nicotine construct a lot of damage to your semen. It can lower sperm fertility and also damage your sperm. Not only may perhaps also leads to lower ejaculation volume. When endeavoring to increase ejaculation volume or thickness, it is you must avoid. | 2,808 | 1,435 | 5,418.363763 |
warc | 202143 | About this Video
Is energy use good…or bad?
In this thought-provoking talk, Rachel Pritzker reveals how most of the comfortable “truths” she had come to believe around climate, energy, and human development were in fact myths she needed to question. Her conclusions illuminate the path to a future in which everyone can enjoy healthy, prosperous lives on an ecologically vibrant planet.
Rachel Pritzker is president and founder of the Pritzker Innovation Fund, which supports the development and advancement of paradigm-shifting ideas to address the world’s most wicked problems. She chairs the Breakthrough Institute Advisory Board and is a board member of the Center for Global Development and Third Way. Rachel also serves on the advisory committee of the Nuclear Innovation Alliance, and is a co-signor of An Ecomodernist Manifesto, which outlines a powerful alternative approach to climate mitigation and human development.
About the Speaker Rachel Pritzker
Rachel Pritzker is President & Founder of the Pritzker Innovation Fund. She is Chair of the Advisory Board of the Breakthrough Institute, a pioneering research institute that is changing how people think about energy and the environment. Rachel is also a board member at Third Way, a multi-issue think tank that answers America’s challenges with modern ideas where she co-founded their Advanced Nuclear Campaign. Rachel is also a member of The Philanthropy Workshop West.
Rachel previously served as a founding board member of Media Matters for America and was a founding board member of the Democracy Alliance, a partnership of business and philanthropic leaders committed to a stronger democracy by supporting progressive organizations. Rachel attended Brown University, where she majored in Latin American studies. A clinical nutritionist by training, Rachel co-founded the nation’s first accredited master’s degree program in botanical medicine. | 1,955 | 970 | 3,853.56701 |
warc | 202143 | Consciousness Coach + Embodiment Teacher + Conscious Business Mentor
Let's get back to simplicity. The science of the five elements comes from old Tibetan, Ayurvedic, and yogic traditions. However, it is very relevant and practical in modern times.
Elements are all around us and in us. By recognizing our unique constitution of the elements, we can become aware of what lifestyle, personal and work-life changes we need to apply, so we feel more grounded, balanced, experience emotional ease, creativity, mental clarity, connection to intuition, energy, and inner power to take action and achieve our intentions in life.
MY METHOD
Diana helps individuals and groups to awaken their purpose, embody their vision and create sustainable success with ease, grace, and flow. Before this, she held innovation consultant and team leader roles at different organizations. After her internal alchemy process, she embarked on her mission to initiate the new methods and approaches in business, personal and spiritual growth while the collective consciousness is rising to a new level.
She utilizes transformational coaching, Akashic Record consultancy, consciousness coaching, Enneagram psychology, mindset training, intuitive astrology, quantum physics, mindfulness, Reiki healing, Ayurveda health system, spiritual psychology, Kundalini and Hatha yoga, and Quantum Flow embodiment methods in her work. She blends her intuitive skills, coaching experience, and expertise in business development and finance to support people from different walks of life in transforming their old stories and moving to the empowered state of being, and expanding in any area of their lives. EARTH
Earth gives us grounding, inner stability, and supports our projects in life.
During the month dedicated to Earth, you will learn and do:
WATER
Water supports natural fluidity, being a flexible and healthy expression of emotions. During the month dedicated to water, you will learn and experience:
AIR
The balanced energy of air gives us mental clarity, focus, ease of making decisions, and connecting with our intuition. During the month of air, you will learn and experience:
FIRE
Connecting with our inner fire gives us a life force to transform the obstacles and challenges in life, strategize, take aligned actions, and connect with a spark of inspiration and joy. During the month of fire, you will learn:
SPACE
Balancing the elements of space allows us to integrate all other elements, so none of them is dominant, open up to a vast view, and experience unity within. During the month of space, you will learn:
’“WOW. My experience with Diana was out of this world. I have never received a reading like this before and it was truly such a unique and special experience for me. We instantly connected and I felt like I was talking with an old friend.
She gave me SO much insight and answers to things that I’ve been dealing with and I can honestly say I feel more confident, secure, and supported on my current path than I ever have.
She has a very magical gift and she was spot on with all of the messages she received about many aspects of my life. I’m so grateful we were brought together, I’ve been feeling a little unsure about where I’m going and what I’m doing, but after our session, I feel lighter and more courageous to take on the path before me. Thank you, thank you, thank you!”
Jennifer Cramer — USA
HOW I DO IT
I have practiced and implemented every single thing that I teach. I am beyond happy to be supported by several mentors and teachers, who I deeply trust and who have shown me my true nature and the path to freedom.
CURIOUS TO KNOW MORE?
Starting a new program can be a big commitment, but your health, your well-being, your dreams, and your visions are worth it. Schedule a
free connection call with me to explore your main elements, and how you can balance them to accelerate and amplify your career, purpose, personal and professional vision of your life.
If you haven't yet, we would like to invite you to listen to our series of talks, meditations, and practices connected to each of the elements. Completely free. Join here. | 4,204 | 2,067 | 8,403.932269 |
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