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André Glucksmann
André Glucksmann (; 19 June 1937 – 10 November 2015) was a French philosopher, activist and writer. He was a member of the French new philosophers.
Glucksmann began his career as a Marxist, but went on to reject communism in the popular book La Cuisinière et le Mangeur d'Hommes (1975), and later became an outspoken critic of the Soviet Union and post-Soviet Russian foreign policy. He was a strong supporter of human rights. In recent years he opposed the claim that Islamic terrorism is the product of the clash of civilizations between Islam and the West.
Early years
André Glucksmann was born in 1937 in Boulogne-Billancourt, the son of Ashkenazi Jewish parents from Austria-Hungary. His father was from Bukovina, which later became part of Romania, and his mother from Prague, which later became the capital of Czechoslovakia.
Glucksmann's father was killed in World War II, and his mother and sister were active in the French Resistance. The family "narrowly escaped deportation to the camps" during the Holocaust, which influenced Glucksmann's developing ideas of "the state as the ultimate source of barbarism".
He studied at the Lycée la Martinière in Lyon, and later enrolled at École normale supérieure de Saint-Cloud. His first book, Le Discours de la Guerre, was published in 1968.
Career
Early career
In 1975 he published the anti-Marxist book La Cuisinière et le Mangeur d'Hommes - subtitled Réflexions sur l'État, le marxisme et les camps de concentration, in which he argued that Marxism leads inevitably to totalitarianism, tracing parallels between the crimes of Nazism and Communism. In his next book Les maitres penseurs, published in 1977 and translated into English as Master Thinkers (Harper & Row, 1980), he traced the intellectual justification for totalitarianism back to the ideas articulated by various German philosophers such as Fichte, Hegel, Marx, and Nietzsche. In the years of the Vietnam War, Glucksmann rose to national prominence after expressing his support for Vietnamese boat people. He began working with Bernard-Henri Lévy criticizing Communism. Both had formerly been well known Marxists. Shortly afterwards they became known, along with others of their generation who rejected Marxism, as New Philosophers, a term coined by Lévy.
1980s and 1990s
In 1985, Glucksmann signed a petition to President Reagan urging him to continue his support for the Contras in Nicaragua. After the fall of the Berlin Wall, Glucksmann became an advocate for the use of nuclear power. In 1995 he supported the resumption of nuclear tests by Jacques Chirac. He supported the NATO intervention in Serbia in 1999. He also called for Chechnya to become independent.
Philosophy
In his book Dostoyevsky in Manhattan, Glucksmann asserts that nihilism, particularly as depicted by Dostoyevsky in his novels Demons and The Brothers Karamazov, is the 'characteristic form' of modern terrorism. Drawing on Ivan Karamazov's dictum that "If there is no God, everything is permitted", Glucksmann argues that:
The inner nature of nihilistic terrorism is that everything is permissible, whether because God exists and I am his representative, or because God does not exist and I take his place.
His 2006 book Une rage d’enfant is an autobiography which talks about how his experiences as a young Jew in occupied France led to his interest in philosophy and his belief in the importance of intervention:
My style of thinking is to compare what happens on the TV, in the news and so on, and then extract what I can from books of philosophers to understand it. Philosophy for me is like subtitles. The problem comes from current events but the answer is supplied by philosophy.
Glucksmann criticises the notion that Islamic terrorism is a product of the clash of civilizations between Islam and the West, arguing that the first victims of Islamic terrorism are Muslims:
Why do the 200,000 slaughtered Muslims of Darfur not arouse even half a quarter of the fury caused by 200-times fewer dead in Lebanon? Must we deduce that Muslims killed by other Muslims don’t count – whether in the eyes of Muslim authorities or viewed through the bad conscience of the West?
Later years
Glucksmann supported military action by the West in Afghanistan and Iraq, and was highly critical of Russian foreign policy, supporting for example Chechen independence. However, he was against the Abkhazian and South Ossetian independence from Georgia, arguing that Georgia is essential to maintaining European Union "energy independence," vis-a-vis Russia, through access to oil and gas reserves in the former Soviet republics: "If Tbilisi falls, there will be no way to get around Gazprom and guarantee autonomous access to the gas and petroleum wealth of Azerbaijan, Turkmenistan, and Kazakhstan".
As proof of Russia's plans to use energy blackmail, Glucksmann referenced a biting anti-Gazprom satirical song performed at the annual satirical award show "Silver Rubber Boot", which made jokes like: "If the Eurovision Song Contest denies victory to Russia again, we are going to drive to their concert and block their gas with our bodies!" Glucksmann cited this as evidence that the Russian people want to cut off gas to Ukraine and Europe. He wrote:
Consider a popular song performed by a military choir in Moscow. Its chorus depicts the "radiant future" that Gazprom is preparing: "Europe has a problem with us? We will cut off its gas..." The Russian public loves the song.
Glucksmann supported Nicolas Sarkozy for the April–May 2007 presidential election.
In August 2008 he co-signed an open letter with Václav Havel, Desmond Tutu, and Wei Jingsheng calling upon the Chinese authorities to respect human rights both during and after the Beijing Olympic Games.
He was a signatory of the Prague Declaration on European Conscience and Communism.
Death
Glucksmann died in Paris on 10 November 2015 at the age of 78.
In reaction to his death, President François Hollande said that Glucksmann always "listened to the suffering of peoples". Former president and opposition leader Nicolas Sarkozy commented on Glucksmann's death by saying: "[Glucksmann] turned a page in French thought from the second half of the 20th Century".
Works
Voltaire counter-attacks (Voltaire Contre-Attaque) (2014)
A Child's Rage (Une rage d'enfant) (2006)
The Discourse of Hate (Le Discours de la haine) (2004)
West Versus West (Ouest contre Ouest) (2003)
Dostoevsky in Manhattan (Dostoïevski à Manhattan) (2002)
The Third Death of God (La Troisième Mort de Dieu) (2000)
Silence, Killing in Process (Silence, on tue) (1986) (with )
Stupidity (La Bêtise) (1985)
Cynicism and Passion (Cynisme et passion) (1981/1999)
The Force of Vertigo (La Force du vertige) (1983)
The Master Thinkers (Les Maîtres penseurs) (1977)
Note: Many of his works were translated into German by his long-term colleague Helmut Kohlenberger.
Interviews
"An Interview with Andre Glucksman". TELOS 33 (Fall 1977). New York: Telos Press
References
External links
Philosopher André Glucksmann: A Dark Vision of the Future of Europe
Category:1937 births
Category:2015 deaths
Category:People from Boulogne-Billancourt
Category:Prix de l'essai laureates
Category:20th-century French philosophers
Category:21st-century French philosophers
Category:Jewish philosophers
Category:French people of Romanian-Jewish descent
Category:French people of Czech-Jewish descent
Category:ENS Fontenay-Saint-Cloud-Lyon alumni
Category:Recipients of the Order of the Cross of Terra Mariana, 3rd Class
Category:Members of the European Academy of Sciences and Arts
Category:Tibet freedom activists
Category:French Maoists
Category:French essayists
Category:20th-century French writers
Category:21st-century French writers
Category:Holocaust survivors
Category:French Zionists
Category:20th-century essayists
Category:21st-century essayists | 2024-05-09T01:26:59.872264 | https://example.com/article/7508 |
William Lawrie
William Lawrie (1881–1916) was a Scottish bagpipe player, who was both an eminent solo competitor and a composer.
Life
He was born into a slate quarrying family in Ballachulish, Argyll and was the son of Hugh Lawrie, (Eòghann Thomais Uilleam) who gave him his first lessons on the Highland bagpipes at the age of seven. He later received lessons from John MacColl of Oban.
In 1910 he became the second piper ever to win the Gold Medals at the Northern Meeting and Argyllshire Gathering in the same year. He was a friend and contemporary of G.S. McLennan, and they travelled to competitions together and shared prize money.
Lawrie spent some time as piper to the Earl of Dunmore, and also as piper to the Colonel MacDougall of Lunga.
In 1914 he became Pipe Major of the 8th Argyllshire Battalion of the Argyll and Sutherland Highlanders and served with them in France from 1915 to 1916 when he became ill as a result of trench conditions. He was invalided to England where he died in the Third Southern General Hospital in Oxford, possibly as a result of contracting pneumonia and pleurisy in the trenches and then meningitis after being admitted to hospital. He left behind his wife Una and three children, who were all aged under five when he died. A 'marbhrann' (gaelic lament) was written upon his death by the Islay bard Duncan Johnston who was a close personal friend.
His bagpipes are now on display in The Argyll and Sutherland Highlanders Regimental Museum in Stirling Castle, along with his service medals and the Gold Medals he won at Oban and Inverness.
Compositions
He is remembered as a composer for the bagpipes although only around twenty of his tunes survive. Some of his compositions are:
The Pap Of Glencoe
The Battle Of The Somme
Inveraray Castle
Captain Carswell
References
Category:Great Highland bagpipe players
Category:People from Ballachulish
Category:Argyll and Sutherland Highlanders soldiers
Category:1881 births
Category:1916 deaths
Category:British military musicians
Category:Gold Medal winners (bagpipes)
Category:Scottish bagpipe players
Category:British Army personnel of World War I | 2024-01-17T01:26:59.872264 | https://example.com/article/9490 |
IMAGE: Joan Coates and her collaborators found that a biomarker test that helps diagnose ALS also can assist with determining a diagnosis for degenerative myelopathy. Coates currently is seeking clinical trial...
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Credit: MU College of Veterinary Medicine
COLUMBIA, Mo. - In 2009, Joan Coates, a veterinary neurologist, along with other researchers at the University of Missouri and the Broad Institute at MIT/Harvard, found a genetic link between degenerative myelopathy (DM) in dogs and amyotrophic lateral sclerosis (ALS), or Lou Gehrig's disease in people. Now, MU researchers Coates and Michael Garcia, an associate professor in the Division of Biological Sciences, have found that a biomarker test that helps diagnose ALS also can assist with determining a diagnosis for degenerative myelopathy.
Coates is seeking clinical trial participants to evaluate a treatment for canine DM.
In dogs, DM is an older adult onset disease that can eventually lead to paralysis. The neurodegenerative disease has been confirmed in more than 30 pure bred dog breeds, such as Pembroke Welsh corgis, German Shepherd Dogs and boxers, as well as mixed breed dogs. The current genetic test for DM can be useful to breeders and veterinarians in identifying risk for the disease; however, it has limitations when diagnosing DM.
"DM is a diagnosis of exclusion, meaning that veterinarians must rule out all other diseases that mimic it before coming to a final diagnosis," said Coates, a professor in the MU Department of Veterinary Medicine and Surgery. "This requires expensive diagnostic procedures such as MRIs of the spinal cord. Now that we know that DM and ALS are related, we are studying ways to diagnose and measure disease progression with similar diagnostic modalities used in ALS patients."
ALS can be tested using phosphorylated neurofilament heavy proteins (pNF-H) that are released into spinal fluid and blood in humans with ALS. These biomarkers are released during the degeneration of spinal tissues making them a good indicator that ALS is present. Coates and co-principal investigator Garcia tested whether the diagnostic tool could be used in canines.
"I was very excited by the idea that there could be another model that might have many more strength than the existing models," Garcia said. "So this was a natural fit for me."
Cerebrospinal fluid and blood samples were collected from DM-affected dogs, including dogs that had a confirmed diagnosis as well as dogs in early stages of the disease. pNF-H concentrations from those samples were compared to samples from age-matched normal dogs and dogs with mimicking diseases.
"We found a significant difference in the DM affected dogs," Coates said. "pNF-H levels were increased in the cerebrospinal fluid of the DM-affected dogs relative to the control groups, indicating that the human ALS test could be used to diagnose DM. These results will enable us to 'scale up' the test to make it more accessible to veterinary community."
Collecting cerebrospinal fluid from patients is more complicated than a blood test, but is less expensive compared to an MRI to make a presumptive DM diagnosis, Coates said. Nonetheless, pNF-H may serve as a diagnostic tool for diagnosis of DM.
Coates also is conducting clinical trial research for treatment of DM. The goals of the therapies being tested is to slow the progression of neurologic signs of DM and improve quality of life. These therapies are in collaborations with other ALS researchers and funded by the ALS Association and National Institutes of Health. The clinical trials are taking place at the MU Veterinary Health Center (VHC) Small Animal Hospital. To inquire about enrolling a dog, contact Coates at coatesj@missouri.edu.
Collaborations among human health and veterinary clinicians and researchers highlights the multidisciplinary, One Health/One Medicine initiative at Mizzou. The concept is a worldwide strategy for expanding interdisciplinary collaborations and communications in all aspects of healthcare for humans and animals where biomedical research discoveries and expanding the scientific knowledge base lead to faster improvements benefitting both humans and our pets.
###
The study, "Cerebrospinal Fluid Levels of Phosphorylated Neurofilament Heavy as a Diagnostic Marker of Canine Degenerative Myelopathy," was published in the Journal of Veterinary Internal Medicine. Christine Toedebusch, a veterinary neurology resident and doctoral candidate, was lead author on the study. The study was funded in part by the American Boxer Charitable Foundation and the American Kennel Club Canine Health Foundation (Grant #2165). The content is solely the responsibility of the authors and does not necessarily represent the official views of the funding agencies.
Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system. | 2024-03-25T01:26:59.872264 | https://example.com/article/3140 |
Carlisle - Buffet Spoons - Under $100 - Black
Buffet Spoons
Buffet Spoons from Ace Mart will help make your operation a success. With one of the largest selections of in-stock Buffet Spoons available, you are sure to find the exact items to meet your particular need. | 2024-03-20T01:26:59.872264 | https://example.com/article/9433 |
BlastyourwaythroughinfinitespaceinCosmos
Cosmos - Infinite Space ($2.99) by Alexander Repty brings classic arcade shoot-em-up action right on your iPhone, iPad, and even Apple TV. If you once lived in the arcade just dumping quarters into the space shooter arcade machines and miss those glorious days, then Cosmos is a fun way to relive that experience. It is similar to other games on the market like Starseed: Origin and Operation Dracula.
Back in the day, when arcades were numerous and fruitful, I always enjoyed going to them and either watching people show off skills that were much better than mine, or just going to the nearest space shooter and just killed some time on that. These were my favorite types of games in the arcade because hey, who doesn’t like flying through space and just shooting lasers at everything and watching foes blow up along the way? So naturally, when I saw Cosmos on the App Store, I was intrigued and had to give it a try for myself.
The graphics in Cosmos are a nice homage to the classic games of yore, featuring 16-bit pixelated sprites for all of the spaceships and space mines. The background of the game is a stark and inky pitch black that is sprinkled with some white stars and nebulas, so the bright and vivid sprites contrast nicely. Animations in Cosmos are smooth and fluid, and I experienced no lag whatsoever on my iPhone 6s Plus. The atmospheric soundtrack is a joy to listen to and it helps pull you into the game, while the sound effects are a fun touch.
While other arcade shooters are based on levels, Cosmos is more of a pure high score chaser and you can play infinitely until you die. Of course, the difficulty will ramp up the longer you survive since more enemies will show up with harder-to-predict movement and behavior patterns. Still, the game does split up the waves into stages, and once you reach the next stage, you can choose to start from that point in a new game. Cosmos features three difficulty levels that you can choose from before you set out, and there will be separate high scores for each. There are also boxes floating around that are power-ups, so make sure to use them to your advantage.
The controls in the game are the one thing I’m not too happy about. In order to move your ship, you drag your finger across the screen to go left, right, or up and down. As you move, the ship fires automatically. I’m not a fan of this control scheme because it feels cumbersome and slow to move around, and I would have to constantly switch my thumb or fingers after a while. I would have preferred a virtual joystick of some kind, because I feel that works best for these types of games. At the moment, there is no way to change the controls either, which is annoying. Hopefully the developer adds some other forms of touch screen controls in future updates.
As if the high score chasing and infinite gameplay is not enough, the game has full Game Center support so you can compete with friends or globally to see who is the best. I would like to see some achievements added in the future, though.
While I love arcade space shooters, the touch controls in Cosmos are my biggest letdown here. I am not a fan of how it is currently set up, though automatically attacking is nice, I hope to see some other options for controls in the future. While the game does support MFi controllers (and the Apple TV Siri remote), it should not be a requirement to fully enjoy the game on iOS. Personally, dual-stick controls work best for space shooters from my experience, and I would like to see that implemented at some point here. Other than that, the retro graphics look nice, the music is fun, and the gameplay is rather challenging. | 2023-11-08T01:26:59.872264 | https://example.com/article/7080 |
/*
* This file is part of OpenModelica.
*
* Copyright (c) 1998-CurrentYear, Linkoping University,
* Department of Computer and Information Science,
* SE-58183 Linkoping, Sweden.
*
* All rights reserved.
*
* THIS PROGRAM IS PROVIDED UNDER THE TERMS OF GPL VERSION 3
* AND THIS OSMC PUBLIC LICENSE (OSMC-PL).
* ANY USE, REPRODUCTION OR DISTRIBUTION OF THIS PROGRAM CONSTITUTES RECIPIENT'S
* ACCEPTANCE OF THE OSMC PUBLIC LICENSE.
*
* The OpenModelica software and the Open Source Modelica
* Consortium (OSMC) Public License (OSMC-PL) are obtained
* from Linkoping University, either from the above address,
* from the URLs: http://www.ida.liu.se/projects/OpenModelica or
* http://www.openmodelica.org, and in the OpenModelica distribution.
* GNU version 3 is obtained from: http://www.gnu.org/copyleft/gpl.html.
*
* This program is distributed WITHOUT ANY WARRANTY; without
* even the implied warranty of MERCHANTABILITY or FITNESS
* FOR A PARTICULAR PURPOSE, EXCEPT AS EXPRESSLY SET FORTH
* IN THE BY RECIPIENT SELECTED SUBSIDIARY LICENSE CONDITIONS
* OF OSMC-PL.
*
* See the full OSMC Public License conditions for more details.
*
*/
lexer grammar Modelica_3_Lexer;
options {
language = C;
}
import BaseModelica_Lexer;
STAR : '*';
MINUS : '-';
PLUS : '+';
LESS : '<';
LESSEQ : '<=';
LESSGT : '<>';
GREATER : '>';
GREATEREQ : '>=';
EQEQ : '==';
POWER : '^';
SLASH : '/';
/* Modelica 3.0 elementwise operators */
PLUS_EW : '.+'; /* Modelica 3.0 */
MINUS_EW : '.-'; /* Modelica 3.0 */
STAR_EW : '.*'; /* Modelica 3.0 */
SLASH_EW : './'; /* Modelica 3.0 */
POWER_EW : '.^'; /* Modelica 3.0 */
/* Modelica 3.1 */
STREAM : 'stream'; /* for Modelica 3.1 stream connectors */
/* Modelica 3.3 */
PURE : 'pure'; /* for Modelica 3.3 pure functions */
IMPURE : 'impure'; /* for Modelica 3.3 impure functions */
| 2024-05-19T01:26:59.872264 | https://example.com/article/3743 |
Drain Care is a highly effective alkali-based organic matter digester. Hence it is useful for removal of blocks in any type of drain pipes. The common cause of blocks in drain pipes is organic matter which also encourages growth of microorganisms. Thus blocks get reinforced and begin to emit foul odor due to microbial activity. Drain care formulation is designed to deal with this problem very effectively.
Available in
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Where to use
Clogged pipelines, water closet, urinal and sink drain pipes.
How to use
Drain Care is a ready to use product. 50 to 100 ml of Drain Care is added to the blocked pipe and allowed to react for 1-2 hours. After this the pipe is flushed with water. If necessary a rubber-cup push device is used to force the flush.
Safety instructions
Drain Care is corrosive. It should not be consumed or allowed to come in contact with skin, eyes or cloth. Use goggles and gloves while handling the concentrate. | 2024-06-21T01:26:59.872264 | https://example.com/article/6922 |
Our October cover star’s latest role may be her best yet.
On a warm summer Friday afternoon, Elle Fanning takes refuge inside Pasadena’s Norton Simon Museum, touring its permanent Edgar Degas exhibition — one of her beloved out-of-the-way spots in Southern California. The actress could be mistaken for one of Degas’s iconic ballerinas: She has a dancer’s body, long and lean, and out of habit she sometimes pirouettes while she talks. Elle, 17, last came here to research a project for her art history class.
“I wrote about Dancers in the Wings,” she says, stopping in front of the painting, which depicts two young women preparing to go onstage. Or maybe they’re just coming offstage. Who can tell? When asked why this is her favorite, she cites the vivid colors and the level of detail, saying, “You can really see their faces,” which, she notes, is somewhat rare for Degas. But there’s more to it, she adds, pointing to one of the girls, smiling as she says, “She’s fixing her shoe.”
That a quiet, small moment like this fascinates Elle isn’t surprising. She has always understood the power of stillness in telling a story. It’s what makes her such a disarming presence on-screen. Whether she’s silently skating on an ice rink in Sofia Coppola’s Somewhere or meeting Angelina Jolie as the title character in Maleficent for the first time in an enchanted forest — eager, taking her in as she emerges from the shadows — Fanning reveals more in repose than most actresses do with reams of dialogue.
Her roles have been so demanding — a mute, an obsessive-compulsive, and a girl grieving over her lost brother — that it’s easy to forget she’s a “child actress,” until she reminds you that her mom dropped her off for this interview. Elle recently got her driver’s license but admits she’s not quite ready for the open road. This is where she’s at today: a woman on the verge. She’s got a memoir from Sally Mann, her favorite photographer, on her bedside table and a Princess Jasmine Band-Aid on her leg. She wears a strapless dress (with a massive Mickey Mouse appliqué on the skirt) from Paul & Joe Sister but carries a Miu Miu purse — a gift from the house of Prada, no less.
All that is to say, she’s a typical 17-year-old — albeit a famous one. That perfect moment of innocence about to fall away is on wondrous display in this month’s About Ray, in which she plays the title role of a transgender skater boy trying to convince his mother (played by Naomi Watts) to let him transition. Portraying the character was daunting, Elle admits. “I never thought about saying no, but I was so afraid to touch it. What if I don’t do it right? I know transgender kids — I am honored to help tell their story.” That was reason enough for a challenge. And so she dug in, speaking with trans kids over Skype and in person, asking questions but mostly listening. She pored over YouTube videos of teenagers in transition, recalling a particularly memorable one that cemented how important this project was: “Someone tracked their time using testosterone shots, and they were so excited to be getting a visible Adam’s apple. They started crying, and it just hit home.”
The work paid off in spades — and could potentially pay off with Oscar acclaim, too. Elle, who is ethereal and über feminine in person, is unrecognizable in costume, recalling Hilary Swank’s Academy Award–winning performance in Boys Don’t Cry. As Ray, short dark hair peeks out of Elle’s ski cap, and her breasts are strapped down with a T-Kingdom binder (which allows more circulation than ACE bandages, she reports). Elle also skateboards like a boss — the result of hours spent falling down and getting back up at Skatelab in Simi Valley.
But the emotional transformation has been even more impressive. Again, she electrifies with stillness. After getting into a fistfight, Ray proudly walks his school’s hallways feeling like he’s survived this very male rite of passage — only to be called a girl by a classmate. In that swift moment, Elle’s face crumbles. She should receive every prize imaginable for that breathless moment alone.
About Ray was shot in a little less than two months in New York during one of the coldest winters in recent memory. It helped that Elle’s older sister, Dakota — a student at New York University — was nearby, and the two could catch up over pizza at Rubirosa in Nolita. For Elle, now in her senior year, being away from home can be stressful. “I miss my friends, for sure,” she explains. “But I don’t think about what I’m going to miss. I just think about what I’m gaining.”
That’s quintessentially Elle Fanning: She acknowledges that life is about give-and-take, but she always clings to the upshot. While she has several movies scheduled to come out in the next year, she has fiercely held on to her time as a teenager, admirably maintaining a normal schooling experience (whatever that means). The professional world may be opening up to her in incredible ways, but she’s still a goofball—a girl as happy to talk about how she hasn’t washed her hair in four days (“I like taking baths!”) or why she can’t go to the beach with her friends (“I just peel and hurt”) as she is to discuss sitting front row at Paris Fashion Week or how much she loves Gucci, praising Alessandro Michele’s resort collection (“It’s very youthful—very girly and floral”).
But she seems to understand on a molec- ular level how rare an experience high school can be, how there’s a difference between playing a teenager on-screen and actu- ally, you know, being one. Earlier this year, she wrapped Nicolas Winding Refn’s The Neon Demon—a creepy Beyond the Valley of the Dolls–inspired story about aging female models feasting on the youth of her character, Jesse—but she insisted the production let her out for prom night.
“The whole set was
excited,” she says.
“They’re like, ‘Elle’s
going to prom!’”
Though she works
with stylist Samantha
McMillen (who also dresses Carey Mulligan and Mark Ruffalo) and surely could have borrowed couture for the night, Elle and her mom went to a bridal store, where she picked out—and paid for—a light pink strapless brides- maid dress. Why the classic approach? “You want to buy the prom dress,” she says. “You want to go with your mom and choose your own.”
For the record, though Elle went to the prom with a “friend,” she has since been linked to Zalman Band (the son of horror royalty Charles Band—the man responsible for the Puppet Master franchise). When I mention the two were recently caught together by the paparazzi, Elle will say only that the attention “makes us laugh a lot.” OK, does she at least like horror movies? “They scare me!” she reveals. “The other night I went to see The Gallows. It was terrifying. I was under a jacket the whole time!”
Like anyone with graduation on the horizon, Elle is looking at a million paths forward and wondering which one to take. In the past, she’s considered going to college, but Elle hasn’t taken the SATs or the ACTs, and she seems to have put the idea on hold for now. “I thought more, and I’m like, Eh. I don’t think it’s for me. That sounds weird because I feel like every-
body goes to college. Maybe I’ll just wait. I’m already doing what I want to do, so why can’t I just...?”
Her voice trails off. Maybe she’s lost her train of thought, or maybe she’s still working it all out in her head. Thankfully she doesn’t need to make a big life deci- sion today. Besides, as an actress she’s more in-demand than ever, and, this fall, she will play Bryan Cranston’s daughter in the biopic Trumbo, about a Hollywood screenwriter black- listed in the 1940s. Ask Elle about her dream director, and the answer is surprising: “Quentin Tarantino would be so cool,” she says, hinting that she’d love to kick ass in something like Kill Bill: “I love Uma Thurman.
She’s a fellow tall girl. I’ve never done anything like that.” Fanning would be prepared for it, though—she takes boxing classes with a friend (which she alternates with ballet and person- al-training sessions). Of class she says, “I really go for it.” She adds with a laugh: “I’m pretty strong. I used to beat up my sister so much. I’m the younger one, but I was always much taller and bigger.”
We’re leaving the museum when I realize I never asked Elle how she did on her Degas assignment, the one about Dancers in the Wings. “I got an A. And I got an A-plus in art history.” We never had a doubt. | 2024-07-09T01:26:59.872264 | https://example.com/article/3936 |
By Adnan Prekic – Podgorica
After the strong reaction of the Russian Foreign Ministry due to the meeting between the Prime Minister of Montenegro, Milo Djukanovic and U.S. Vice President Joe Biden, another threat came to Podgorica from Moscow. Unlike the official statement of the Russian Ministry in which the policy of Montenegro’s accession to NATO was called “hostile”, this time the threats refers to the sanctions. Russian media close to the Kremlin reported that Moscow is preparing a response to Montenegro’s decision to support European Union sanctions against Russia.
Official Russian policy did not stop just at the harsh statement about the attitudes of Montenegro. While visiting the United States, Prime Minister Milo Djukanovic clearly stated that the EU and NATO integration are first priorities of Montenegro. In addition to a clear deviation from Moscow, Djukanovic, by joining the sanctions that Brussels has brought to Russia, has clearly marked the foreign policy priorities of Montenegro.
As reported by the government newspaper “Rossiyskaya Gazeta”, Moscow is thinking about how to respond to the policy of Montenegro. The visa requirements for Montenegrin citizens traveling to Russia could be the first measure, but economic sanctions also come into consideration. “Rossiyskaya Gazeta” claims that Russian money from tourism and investment accounts forms the largest part of the Montenegrin GDP. The range of measures which can be applied are wide – from changes in the conditions of import of wine from Montenegro, to the introduction of the visa regime that may affect the flow of tourists from Russia, which accounts to a third of all foreign tourists.
The daily newspaper “Rossiyskaya Gazeta” that informs about the attitudes of the Russian government, reports that despite the centuries-long friendship with the Russian people and the opposition of the majority of Montenegrin citizens for entry into NATO, the leadership in Podgorica joined in the sanctions against Moscow. According to the article, the Russians are secretly pushed out from all aspects of life in Montenegro, although in recent years they have put into it about two billion euros. It is noted that the majority of the population is pro-Russian orientated, but that during the last few years, “efforts of the international political technologists led pro-Russian forces in the government to the absolute minority”. Chairman of the Duma Sergei Naryshkin said that the progress of relations between Russia and Montenegro should not be held hostage to other major geopolitical interests and plans of third parties, especially the ones overseas.
The Montenegrin Ministry of Foreign Affairs once again did not want to comment on the allegations from Moscow. Montenegro has, pursuant to the obligation of the Association Agreement, joined the conclusions of the Council of the European Union, which has frozen the assets and imposed a travel ban on several dozen Ukrainian and Russian politicians and businessmen, who are held responsible for compromising the territorial integrity of Ukraine. | 2023-09-05T01:26:59.872264 | https://example.com/article/8475 |
Carl Simon
Carl Leonard Simon, born 17 October 1973 in St John's, Antigua, is a West Indian cricketer who has played first-class and List A cricket for the Leeward Islands.
References
Category:1973 births
Category:Living people
Category:People from St. John's, Antigua and Barbuda
Category:Leeward Islands cricketers
Category:Antigua and Barbuda cricketers | 2024-02-08T01:26:59.872264 | https://example.com/article/5485 |
Aspiring blockchain-based regulated bank BABB headquartered in London’s Canary Wharf district has announced a new addition to its team. Demetrios Zamboglou joins BABB as its Chief Operating Officer (COO) from a previous role with ICON Capital Reserve – a fintech company focused on synergizing the value of gold with blockchain technology.
The fintech accelerator has raised around 20,000 Ether (initially valued at USD 20m) in capital and is actively working to relay financial services into the hands of individuals and businesses worldwide. BABB will use biometrics including facial and voice recognition, to provide individuals with secure banking services while facilitating organizations to engage in frictionless trade, partly aided by financial product offerings provided by BABB.
BABB has announced its intention to create a “bank for everyone” and a “world bank for the microeconomy”. Zamboglou is forming a key part of the company’s broader market strategy. As the company’s new COO, Zamboglou will focus exclusively on delivering BABB’s operational strategy as well as structuring its market operations.
The iFX EXPO is Back in Limassol!
His past experience and forward-looking operational philosophy are analogous to that of BABB founder and CEO Rushd Averroes. Zamboglou and Averroes are both committed to building a blockchain-powered bank that serves the world’s microeconomy with Zamboglou keen to utilize his extensive FinTech experience in order to make this ambition a reality.
“I have been privileged to work in the financial services industry for more than a decade. My most recent experience has been focused on developing a variety of blockchain-related projects that are orientated towards harnessing the unique power of blockchain to serving the global community,” said Zamboglou.
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“This is the first time in my life that I am able to make a significant contribution to society, so I am honored by the opportunity to work with BABB and the chance to fulfill the potential made possible by blockchain technology. Joining BABB was a no-brainer,” elaborated the longtime fintech industry executive.
Fintech Experience
Having obtained the majority of his experience in trading and investments, Zamboglou will provide in-depth knowledge and understanding of exchanges, brokers and investment firms, as well as how to create profit centers. Demetrios Zamboglou holds a Ph.D. in Behavioural Finance from King’s College London, supplemented by more than a decade’s industry experience where he worked for several fintech start-ups, brokers and top-tier investment firms.
Under his leadership, BABB will launch a purpose-built user-focused application, and over time, will develop the functionality required that will allow the app to be scaled for millions of users.
Zamboglou has won several prestigious awards for his entrepreneurship and has obtained grants from industry giants such as Microsoft and Amazon. He has also participated in renowned conferences as a speaker and a panelist, most notably at the St. Petersburg International Economic Forum in 2018.
Rushd Averroes, CEO of BABB, said: “I am very pleased to have Dr Zamboglou as part of the Babb team. We have big ambitions to make a global impact on the financial market, and Dr Zamboglou’s background and experience embody the kind of people that we seek to have in order to drive our activities forward.” | 2024-04-05T01:26:59.872264 | https://example.com/article/7475 |
nded to the nearest one hundred thousand?
-441000000
Round -37058.7 to the nearest 10000.
-40000
What is -10171.3122 rounded to the nearest 100?
-10200
Round -15.91013 to 1 decimal place.
-15.9
What is -324.0455 rounded to zero dps?
-324
Round 0.000992514 to six dps.
0.000993
What is 22.49853 rounded to zero decimal places?
22
Round 0.00928538 to four decimal places.
0.0093
Round -40.99869 to two decimal places.
-41
What is -74446100 rounded to the nearest 100000?
-74400000
Round 0.432042 to 2 dps.
0.43
Round 0.5695549 to 3 decimal places.
0.57
What is -500005.6 rounded to the nearest ten thousand?
-500000
Round 3123527 to the nearest 100000.
3100000
What is -19199685 rounded to the nearest 1000000?
-19000000
What is -12.388064 rounded to 1 dp?
-12.4
Round -3036470 to the nearest 100000.
-3000000
What is -2.45139 rounded to 2 decimal places?
-2.45
Round -8586.013 to zero decimal places.
-8586
What is 0.000583556 rounded to 6 dps?
0.000584
Round -1.775267 to two decimal places.
-1.78
What is 0.00258181 rounded to 6 decimal places?
0.002582
Round 1732790 to the nearest one hundred thousand.
1700000
Round 395341.92 to the nearest one hundred.
395300
What is 265097000 rounded to the nearest 1000000?
265000000
What is -18640527 rounded to the nearest one hundred thousand?
-18600000
Round 0.000781296 to four decimal places.
0.0008
Round -0.3320296 to 2 decimal places.
-0.33
Round -0.0000002777311 to seven dps.
-0.0000003
Round -8102620 to the nearest 1000000.
-8000000
What is -0.0000868879 rounded to 6 dps?
-0.000087
Round 0.000082993 to six decimal places.
0.000083
What is -0.00005131625 rounded to 5 dps?
-0.00005
What is 0.04305422 rounded to two decimal places?
0.04
Round 0.007544536 to three decimal places.
0.008
What is -0.9605511 rounded to two decimal places?
-0.96
What is -0.78935 rounded to two decimal places?
-0.79
What is 0.00001409625 rounded to seven dps?
0.0000141
What is 1.98218 rounded to two decimal places?
1.98
What is 0.00002558646 rounded to 7 dps?
0.0000256
What is -747.65293 rounded to the nearest ten?
-750
What is 6560680 rounded to the nearest 10000?
6560000
Round 0.00011773644 to 5 dps.
0.00012
What is 2.947654 rounded to 3 decimal places?
2.948
Round -2413719000 to the nearest one million.
-2414000000
What is -0.00143373 rounded to 4 dps?
-0.0014
What is 386222.06 rounded to the nearest ten thousand?
390000
Round -47127.9 to the nearest 10000.
-50000
What is -0.0007326987 rounded to seven dps?
-0.0007327
Round -4.2367228 to 0 dps.
-4
Round 1.82123 to the nearest ten.
0
Round 270055.1 to the nearest one hundred.
270100
What is 436.65 rounded to the nearest ten?
440
Round 2204884.8 to the nearest 1000.
2205000
Round 0.000001435528 to seven decimal places.
0.0000014
Round -0.00000950172 to 6 decimal places.
-0.00001
What is 0.000157735 rounded to five dps?
0.00016
Round 0.00002336603 to seven dps.
0.0000234
What is 2.23681 rounded to 2 decimal places?
2.24
What is -78794.42 rounded to the nearest one hundred?
-78800
What is 0.000004199379 rounded to seven decimal places?
0.0000042
What is 11776830 rounded to the nearest 100000?
11800000
Round -95389100 to the nearest 100000.
-95400000
What is 0.00033604026 rounded to 5 decimal places?
0.00034
Round -0.0002145159 to 6 dps.
-0.000215
Round -255867.84 to the nearest 1000.
-256000
Round -9.2123 to 1 decimal place.
-9.2
Round 0.0000001643344 to seven dps.
0.0000002
Round 0.000497113 to five dps.
0.0005
Round 0.0000226734 to seven decimal places.
0.0000227
What is -0.0000505259 rounded to seven dps?
-0.0000505
Round -5132.35 to the nearest 100.
-5100
Round 0.00012098187 to 5 decimal places.
0.00012
Round -398085.4 to the nearest one thousand.
-398000
Round -0.7005908 to one dp.
-0.7
What is 0.000127436 rounded to six dps?
0.000127
Round -0.00001326294 to 7 decimal places.
-0.0000133
What is 20656.55 rounded to the nearest 1000?
21000
What is 3366804 rounded to the nearest 1000?
3367000
What is -542359.82 rounded to the nearest one hundred thousand?
-500000
What is -0.014873252 rounded to four dps?
-0.0149
What is 1420400.6 rounded to the nearest one hundred thousand?
1400000
Round 6.98364 to one dp.
7
What is -32466400 rounded to the nearest 100000?
-32500000
Round 55827.9 to the nearest 10000.
60000
What is -0.00036358586 rounded to four decimal places?
-0.0004
Round -0.00771939 to three decimal places.
-0.008
Round -0.0000006527436 to 7 decimal places.
-0.0000007
Round 5532742 to the nearest ten thousand.
5530000
Round 0.00173988 to four dps.
0.0017
Round 16099610 to the nearest 100000.
16100000
Round -121.45302 to 1 decimal place.
-121.5
What is -3651273 rounded to the nearest 1000?
-3651000
What is -113784.76 rounded to the nearest ten thousand?
-110000
What is 0.004155893 rounded to 4 decimal places?
0.0042
Round 0.0365986 to four dps.
0.0366
Round 1.1319869 to 3 dps.
1.132
What is -0.00002059783 rounded to six decimal places?
-0.000021
Round 0.025741198 to 5 dps.
0.02574
What is 0.4530661 rounded to 1 dp?
0.5
Round -0.005951387 to five decimal places.
-0.00595
What is -59576.82 rounded to the nearest one hundred?
-59600
Round -4252.21 to the nearest ten.
-4250
What is 83.3191 rounded to 0 dps?
83
What is -1703.2 rounded to zero dps?
-1703
Round 2555.263 to zero decimal places.
2555
What is -1070.377 rounded to the nearest 100?
-1100
Round 11.169473 to 2 decimal places.
11.17
What is 26485.88 rounded to the nearest 100?
26500
What is 0.000004489536 rounded to six dps?
0.000004
What is -0.02402057 rounded to 5 dps?
-0.02402
What is -0.05224417 rounded to four decimal places?
-0.0522
Round 39.0024 to the nearest ten.
40
Round 0.000002775935 to 7 dps.
0.0000028
Round -0.012578444 to five decimal places.
-0.01258
Round 4.941677 to two decimal places.
4.94
Round 1.52708 to 3 dps.
1.527
What is 67461330 rounded to the nearest 10000?
67460000
What is -0.0040578448 rounded to six decimal places?
-0.004058
Round 185166210 to the nearest 1000000.
185000000
What is 1.620213 rounded to two decimal places?
1.62
Round -0.000006788688 to 6 dps.
-0.000007
What is -0.0006324548 rounded to six dps?
-0.000632
What is 0.00303923 rounded to 5 dps?
0.00304
Round -14220100 to the nearest 10000.
-14220000
What is 0.000066088 rounded to six dps?
0.000066
Round 0.000273565 to four decimal places.
0.0003
Round -8211.77 to the nearest 100.
-8200
What is 545.4286 rounded to the nearest ten?
550
What is -38645000 rounded to the nearest 1000000?
-39000000
What is -2018038 rounded to the nearest ten thousand?
-2020000
What is -0.1409453 rounded to 3 dps?
-0.141
Round 23069000 to the nearest one million.
23000000
What is 69766.8 rounded to the nearest 1000?
70000
What is 0.000000420452 rounded to 7 dps?
0.0000004
What is -30088.595 rounded to the nearest ten?
-30090
Round 0.4964782 to 3 decimal places.
0.496
Round -34810.148 to the nearest 10.
-34810
What is 48418080 rounded to the nearest 1000000?
48000000
What is -3385034000 rounded to the nearest 1000000?
-3385000000
Round -1.0273669 to zero dps.
-1
What is -10064.607 rounded to the nearest one thousand?
-10000
What is 9.6731092 rounded to one decimal place?
9.7
Round 10551.22 to the nearest one thousand.
11000
What is -1576.826 rounded to the nearest ten?
-1580
What is -1230.57 rounded to the nearest 1000?
-1000
What is 2.1020331 rounded to 3 dps?
2.102
Round 9.2812 to 2 decimal places.
9.28
What is -724300 rounded to the nearest 1000000?
-1000000
Round -0.00002321771 to 6 decimal places.
-0.000023
What is -0.0067 rounded to five decimal places?
-0.0067
Round -42476 to the nearest one thousand.
-42000
What is 1161.955 rounded to the nearest ten?
1160
Round 0.000153993 to 4 dps.
0.0002
Round 706.8477 to the nearest ten.
710
Round 3594.619 to the nearest ten.
3590
What is -0.0800976 rounded to 4 decimal places?
-0.0801
Round 396.7862 to one decimal place.
396.8
Round 0.10120998 to 2 decimal places.
0.1
What is -193.7113 rounded to the nearest 10?
-190
Round 34777610 to the nearest one million.
35000000
What is 0.00000556378 rounded to seven dps?
0.0000056
What is -0.000009851 rounded to six decimal places?
-0.00001
What is 0.00553284 rounded to 4 dps?
0.0055
What is 4.7836905 rounded to 1 dp?
4.8
What is -2049940 rounded to the nearest 1000?
-2050000
Wh | 2023-10-17T01:26:59.872264 | https://example.com/article/6593 |
omposite?
True
Let v(u) = u**2 + 3. Let a be v(-4). Let y = 24 - a. Suppose -4*w + y*s + 360 = -0*w, -4*w = s - 336. Is w composite?
True
Suppose -6*q + 3991 = 289. Suppose -p - 66 = -q. Is p a prime number?
False
Let g = 1253 + -3512. Is (5/(-15))/(3/g) a prime number?
True
Is (-7 - -4)/(6/(-4)) - -983 composite?
True
Let z(q) = q**3 + 16*q**2 - 7*q - 33. Is z(14) composite?
False
Let i(d) = d**3 - 5*d**2 - 15*d + 7. Let q be i(7). Suppose 8*r - 2*r - 1830 = q. Is r composite?
True
Let x = -4 - 2. Let q be (x/(-5))/((-2)/5). Is (-787 - -1)/q + -3 composite?
True
Let n(z) be the first derivative of z**5/30 + 3*z**4/8 + 13*z**3/6 + 3*z**2 - 4. Let i(p) be the second derivative of n(p). Is i(-6) a composite number?
False
Let v be (-3)/((-6)/(-14))*-1. Let g = 12 + v. Suppose -5*s + 31 = -g. Is s a composite number?
True
Let v be 3/9*(7 + 5) + 365. Let l = v + 100. Is l composite?
True
Suppose -f - 2 + 6 = 0. Suppose f*z = 185 + 27. Is z a composite number?
False
Let g(k) = 99*k - 10. Let u(r) = -198*r + 21. Let a(h) = 13*g(h) + 6*u(h). Is a(7) a composite number?
True
Suppose -4*k + 852 = -3*w, -w + 567 = -3*w + 3*k. Let m = 137 + w. Is (-15)/(-10) - m/2 composite?
True
Let a(d) = -d**2 - 1. Let c(n) = -8*n + 11. Let x(y) = -5*a(y) + c(y). Is x(-11) prime?
True
Let u(y) be the third derivative of -y**6/240 - y**5/40 - y**4/12 + 3*y**2. Let k(w) be the second derivative of u(w). Is k(-3) composite?
True
Let l be ((-120)/(-42))/((-2)/(-14)). Suppose 0 = -5*r - u + l, -3*u - 5 = 3*r + u. Suppose 2*x - 165 = -5*c, -c - 3*x + 21 = -r*x. Is c prime?
True
Let d = -40 - -105. Let s = 308 + d. Is s a prime number?
True
Is (-100425)/(-20) + -5 + (-3)/(-4) composite?
True
Let x = 18 + -14. Suppose x*n = -n + 385. Is n a composite number?
True
Let p(s) = -s**3 - 8*s**2 - 8*s - 1. Let l be p(-7). Let v be 3*(8/3)/4. Is (1/v + 2)*l prime?
False
Let f be (-4 - -3)/((-1)/(-117)). Let o = 260 + f. Is o a prime number?
False
Let k(h) = -h**3 + 4*h**2 + 2*h + 3. Let o be k(4). Let q(j) = 114*j**2 + 8*j + o - 115*j**2 + 3. Is q(8) a prime number?
False
Suppose 5*x - 5*a = 99725, -7*x - 79780 = -11*x + 3*a. Is x prime?
False
Suppose u = 5*x - 310, 3*u - x = 6*u + 978. Let v = 576 + u. Is v a prime number?
True
Let b = -9093 + 36520. Is b prime?
True
Let c(y) = 47*y - 28. Is c(13) a composite number?
True
Suppose -75*c + 15*c + 2157780 = 0. Is c composite?
False
Suppose m = 3*b - 99832, -133131 = -4*b - 6*m + 3*m. Is b a composite number?
True
Suppose 2*f - 4*h = 10090, 2*f - 6*f + 3*h = -20200. Is f a composite number?
True
Suppose -17*u + 14*u + 132 = 0. Suppose 2049 - u = 5*x. Is x prime?
True
Let q(b) be the first derivative of -b**4/2 - 2*b**3 - 6*b - 5. Let d be q(-8). Suppose -d = -5*f - 0*f + z, -378 = -3*f + 3*z. Is f a prime number?
True
Let o = 5 + -5. Suppose o*g + 5*c + 55 = -5*g, -4*g - 44 = -5*c. Is 9 + g + 89*1 composite?
True
Suppose -8 - 4 = -4*r. Let k = 37 + -35. Suppose 0 = -k*z - 2*z - 2*g + 1056, 3*z = r*g + 801. Is z composite?
True
Let p be 12/10*(-8)/(32/60). Let d = p + 141. Is d prime?
False
Suppose 15*z - 152358 = -37863. Is z a prime number?
False
Suppose 3*z + 1 = -4*y - 12, 5*z - 2*y + 39 = 0. Let i(f) = 18*f**2 - f - 10. Let k be i(z). Is 32/(-8)*k/(-12) a composite number?
False
Suppose 2971 = 4*p - 1473. Suppose 3*r - z - 230 = 443, -p = -5*r - z. Is r a composite number?
False
Suppose p - 2*i = 2*i - 22, 5*i - 77 = 4*p. Let d be p/27 + (-22)/(-6). Let z(t) = 4*t**3 + 4*t**2 - 4*t - 1. Is z(d) a composite number?
False
Let z(c) = c**2 - 7*c + 12. Let o be z(6). Let u be (-1)/3 - 4/o. Is (u - -2) + (-440)/(-4) a prime number?
False
Let c(n) = -57 + 13*n**2 - 55 + 100 - 4*n. Is c(5) a composite number?
False
Suppose -51*v + 48*v = -6933. Let i = v - 1052. Is i a composite number?
False
Suppose -9028 = 7*g - 11*g. Is g composite?
True
Suppose 0 = -10*m + 33461 + 25529. Is m a prime number?
False
Let v = 174 + -97. Suppose -82*j = -v*j - 5965. Is j a prime number?
True
Let o = 2211 + 85. Let j = -1377 + o. Is j composite?
False
Let l = 31946 - -755. Is l a prime number?
False
Is (-5)/90*3 - (-72175)/6 a composite number?
True
Let r(b) = 6*b - 2. Let h be (-14)/(-49) + 164/14. Let m be r(h). Suppose -5*x + 705 = m. Is x prime?
True
Suppose p = i + 1 + 7, -5*i = 0. Let v be p/(-7 - -3) + 6. Let s(j) = 82*j + 1. Is s(v) prime?
False
Suppose -10 = -3*a - 3*n + 2, a - 10 = -4*n. Suppose -a*u = -0*r + 5*r - 7508, r - 1506 = 4*u. Is r prime?
False
Suppose -3*m + 13 = 1, 0 = -3*c - 2*m + 5189. Is c a prime number?
False
Is ((-13956)/24)/(4/(-8)) prime?
True
Let k(h) = 36*h**2 - 3*h + 41. Is k(-18) a composite number?
True
Let k(u) be the second derivative of u**5/20 + u**4/6 - 2*u**3/3 + 1535*u**2/2 + 40*u. Is k(0) composite?
True
Let z(m) = 319*m + 2. Let s(i) = i - 3. Let t be s(4). Is z(t) composite?
True
Is 71871/45 - ((-51)/(-45) + -1) a prime number?
True
Suppose 59*h - 195128 = 51*h. Is h prime?
True
Let y = 34198 - 21595. Is y a composite number?
True
Let m(f) = 998*f - 25. Is m(4) composite?
False
Suppose -5*m + 9694 = 3*y, 3872 = -0*m + 2*m + 4*y. Suppose 2*n = -5*p + 4871, 3*p + 2*n + m = 5*p. Is p a composite number?
True
Let j be 10/25*(-410)/(-4). Let y = 48 - j. Let l(d) = d**3 - 3*d**2 + 9*d + 15. Is l(y) prime?
False
Suppose 4*g - s - 75217 = 0, -4*g - 18817 = -5*g - 4*s. Is g a composite number?
True
Let l(x) be the first derivative of 417*x**2/2 + 43*x - 10. Is l(4) a composite number?
True
Suppose -4*t = -2*i + 5*i - 16184, 0 = 3*i - 2*t - 16208. Let u = i - 2867. Is u composite?
True
Let b be 1*2*(-39)/(-6). Suppose -3*d = 2*z - 5*d - 14, -d + b = z. Is z a prime number?
False
Is (-6)/(-3 - 0)*30715/10 a composite number?
False
Let b(u) = u - 8. Let t be b(8). Let m(v) = v + 287. Is m(t) prime?
False
Let r = 5981 + -4165. Suppose -5*p - r = -4*a, -5*a - 2*p + 2253 = -4*p. Is a composite?
False
Let c be 3/4*(-5 - -9). Let n(o) = 15*o + 8. Is n(c) prime?
True
Let m be 2*(0 - 1/(-2)) + 12. Suppose -20629 - 116638 = -m*f. Is f a prime number?
True
Let d = 185 - -3. Suppose t - 437 = -2*g + d, t - 4*g - 643 = 0. Is t a prime number?
True
Let m = 395 + 2. Is m composite?
False
Let f(u) = u**2 - u + 1. Suppose -3*q + 44 = -5*b + 9, -q + 1 = b. Let a be f(b). Suppose w = 2 + a. Is w a composite number?
False
Let r = 15 + 190. Suppose 0 = -5*u - 4*d + 1025, d + r = -2*u + 3*u. Is u a prime number?
False
Suppose 3 = j, -5*j - 42122 - 8952 = -s. Is s a composite number?
True
Suppose -7851 = -h - 3*s, 3*h + 2*h - 39255 = 5*s. Is h a prime number?
False
Let o be 4/(-18) - (-1)/(9/(-43)). Is (-3)/o - 10828/(-20) a prime number?
False
Suppose 52*v + 5*z + 317897 = 55*v, -3*z = -4*v + 423870. Is v prime?
False
Suppose -5*d + 2498 = 8848. Let u = d - -1878. Suppose 4*j - u = -28. Is j composite?
True
Let z(o) = o - 7. Let b be z(-12). Let n = -19 - b. Suppose -r + 566 = c - 2*r, n = -3*c - 4*r + 1691. Is c composite?
True
Suppose -d - 7663 = -98*d. Is d composite?
False
Suppose 2*w + 21 = 5*w. Suppose w = d - 10. Let z(r) = r**3 - 16*r**2 - 11*r - 23. Is z(d) prime?
True
Let y = 2 - 16. Let n be (-188)/6*(-1 + y). Suppose 0 = -5*d + 3*d + n. Is d composite?
True
Let q = 9051 - 1282. Is q composite?
True
Let w be -4 + 4 + -23 + 1 - -4. Let o(c) = -c**3 - 19*c**2 - 24*c - 23. Is o(w) a composite number?
True
Let i = 5 + -8. Is (-5 - 218)/(3/i) prime?
True
Is 4 - (354825/(-5))/3 a prime number?
False
Let v be (5 - -2)*(-1 - 0). Let g = v + 49. Let a = g + -9. Is a prime?
False
Let i(t) = -t + 1. Let q be i(-1). Suppose 4*p - 2*b - 10228 = q*b, -5*b = 0. Is p a composite number?
False
Suppose -52*b = -49*b - 894. Suppose -2*c + 2016 = b. Let k = c - -336. Is k prime?
False
Let m(s) = 32*s**2 - 7*s + 4. Let t be m(-6). Suppose -t = -4*v - 5358. Is 6/14 - v/7 composite?
False
Suppose 3 = -2*n + 11. Is (3628/(-10))/(90/25 - n) a prime number?
True
Let m(b) = b**2 - 13*b + 3. Let u be m(13). Let l(g) = -g**2 + g + 6. Let p be l(u). Suppose p = o + k - 331, 844 = 2*o + 5*k + 191. Is o composite?
True
Let k(f) = -3*f - 9. Let z be k(-4). Suppose -2*w - z*u = -1054, -2*w + 2*u + 2597 = 3*w. Is w a prime number?
True
Let o(b) = -19*b**3 - 2*b**2 - 15*b - 15. Let k(r) = 10*r**3 + r**2 + 7*r + 8. Let j(l) = 5*k(l) + 3*o(l). Is j(-4) prime?
True
Supp | 2024-03-18T01:26:59.872264 | https://example.com/article/4781 |
Pappy
Pappy was the first of the Popeye gang to depart for their new lives. He was adopted by Carl Teague from San Marcos, Texas, who has waited patiently for Pappy to finally be ready to be adopted. He will have a very excited brother named Tyson to pal around with, and he will live out in the country and be a spoiled little man.
Carl told us his name shall remain Pappy and since he is already on the Happy Tails page, we will all be able to watch this handsome boy enjoy a new life free of a puppy mill.
Happy life Pappy!
About Pappy:
Pappy was rescued with the entire Popeye gang from a mill owner in Oklahoma. He’s estimated to be around 4 to 5 years old and is currently getting his vetting taken care of.
UPDATE from his foster mom:
Pappy came with Popeye and they could possibly be litter mates–very similar cobby bodies and coloring and age. Pappy’s face is stunning and he loves to eat. He is not particularly interested in squeaky toys yet, but does love to ffrenchie wrestle with the other dogs. Cats are ignored most of the time–other times when they catch his eye, he is just curious and one hiss from a cat and Pappy quickly retreats and occupies himself with something else. We are very close to walking on leash, but I have to catch him first to put the leash on! Pappy, as can be imagined, came to my house very leery of humans, but soon learned that I could be trusted, and now loves the human touch. | 2024-07-21T01:26:59.872264 | https://example.com/article/8463 |
44710009
-75158 times 461
-34647838
-0.2 times -209610.8
41922.16
2452.31283 * 0.4
980.925132
Multiply -1.119 and -65.19.
72.94761
-0.042 * -21.81546
0.91624932
Product of -0.88117 and -9.
7.93053
Product of 3 and 0.0901743.
0.2705229
Calculate 19478149*-0.23.
-4479974.27
What is the product of 125539 and 0.04?
5021.56
Product of 22 and 488809.
10753798
What is 0.31 times 151634.33?
47006.6423
What is -24873 times -0.030344?
754.746312
Product of -937 and 6703.
-6280711
What is the product of 1.363231 and 142.2?
193.8514482
What is the product of -6189 and 28.8?
-178243.2
312 times -1.99318
-621.87216
Calculate 0.11304*-3.181.
-0.35958024
Calculate -94653371*-0.2.
18930674.2
Product of 1.782175 and 1.33.
2.37029275
Multiply -47 and -1309629.
61552563
382251399*0.5
191125699.5
Work out -12 * 3424372.
-41092464
Calculate -0.1*-12643723.2.
1264372.32
What is the product of -6 and -1350753.6?
8104521.6
-66.7528 times 0.026
-1.7355728
Work out -38 * 155142.
-5895396
Product of -6.03275 and -0.05.
0.3016375
-77.92*-1114
86802.88
7828593.5 times 0.1
782859.35
What is -2161 times 10867?
-23483587
Product of 3 and -2217.4744.
-6652.4232
What is 1083.252 times 0.3?
324.9756
Product of 3663 and -8721.
-31945023
110.3832 * 152
16778.2464
Calculate 524881*0.3.
157464.3
Product of 0.56 and -13.13519.
-7.3557064
3401708 times 3.9
13266661.2
-0.0418 * -1030311
43066.9998
What is -148 times 1706252?
-252525296
Calculate 0.4*-806807.9.
-322723.16
Work out -2 * -270199.8.
540399.6
Calculate 15627170*11.
171898870
324.2936*21
6810.1656
Product of 0.257 and -2.5453.
-0.6541421
What is -22360606 times 2.5?
-55901515
-1.41 times -4271.591
6022.94331
What is -0.7 times -11290276?
7903193.2
Work out 12.4368 * -0.7.
-8.70576
Work out 0.733 * 4108.04.
3011.19332
What is the product of 2.193 and 1.44?
3.15792
What is the product of 30576 and -0.0015?
-45.864
Product of 145609866 and -0.5.
-72804933
Multiply 302 and -197.36.
-59602.72
Work out 19.988 * -1854.
-37057.752
3671.793 times -8
-29374.344
Product of -2725 and 6106.
-16638850
-4*1902941
-7611764
1.026 * -9543
-9791.118
Product of 169.8 and 8037.
1364682.6
What is 86162.66 times -22?
-1895578.52
0.2 * 0.061185894
0.0122371788
Product of 0.5 and 3969795.9.
1984897.95
Multiply -31575 and 0.194.
-6125.55
98 * -475368
-46586064
-3948709*221
-872664689
-5646*0.1684
-950.7864
Work out -0.0097 * -97792.
948.5824
Work out 0 * 39854.16.
0
-86315*-118
10185170
Product of 195 and -2.8582.
-557.349
What is the product of -997 and 2445.55?
-2438213.35
Calculate 0.61692*-5.7.
-3.516444
Multiply -171971 and -2.7.
464321.7
Calculate -137362*80.7.
-11085113.4
What is the product of -128335 and -10.8?
1386018
0.605214 times -1.65
-0.9986031
Work out -77.5 * -8270.18.
640938.95
-15533 times -421
6539393
Calculate -0.9*-3304531.
2974077.9
Product of 0.01982 and 0.3832.
0.007595024
Work out 43.367419 * -0.2.
-8.6734838
Product of -642086.1 and 0.
0
21*245072
5146512
Multiply -338866 and -0.061.
20670.826
What is the product of 0.7 and -13772549?
-9640784.3
What is 126 times -121506?
-15309756
What is 24 times -780719?
-18737256
Calculate -89.1852*8.
-713.4816
-0.5 times 16216836
-8108418
63409183*5
317045915
Multiply 0.007 and 0.091563.
0.000640941
What is the product of 35 and 246.546?
8629.11
What is the product of -2564813 and 1.7?
-4360182.1
0.22*-106.8509
-23.507198
Multiply -2.412929 and -0.02.
0.04825858
-520154 times 68.6
-35682564.4
Calculate -217*291051.6.
-63158197.2
-0.3*-64419304
19325791.2
What is 27750.7 times -24?
-666016.8
Calculate 568072*-6.
-3408432
Product of 8297308 and 5.
41486540
Calculate 0.074*348560.6.
25793.4844
Multiply 1.2 and 3620281.
4344337.2
Work out 213 * 171.096.
36443.448
What is 767 times 71402?
54765334
Work out 0.036048 * 0.0791.
0.0028513968
Work out 25.89337 * 26.
673.22762
-494.9*0.99909
-494.449641
5303154 * -0.5
-2651577
10.4475 * 372
3886.47
Product of 11.46 and 8523.
97673.58
What is -3.096083 times -14?
43.345162
Work out -55.3 * 1691.2.
-93523.36
Multiply 0.7 and 0.044512863.
0.0311590041
What is -4174187 times -0.2?
834837.4
What is 0.017 times -118304?
-2011.168
Multiply -102543 and -29.
2973747
Multiply -46630724 and -0.1.
4663072.4
Multiply 4 and 2473.581.
9894.324
22839 times 228
5207292
What is the product of -0.4 and -48.1508?
19.26032
0.00838*-9231
-77.35578
What is the product of -348 and 0.5526?
-192.3048
What is the product of -96514.4 and -0.964?
93039.8816
What is the product of 726 and -315.7?
-229198.2
Work out -118 * 57.5351.
-6789.1418
What is 8714.268 times 4?
34857.072
61246 times 308.5
18894391
Product of -0.3 and -3423160.
1026948
-295169 * 0.04
-11806.76
What is the product of 1 and -0.6168123?
-0.6168123
Product of 209.859 and -142.
-29799.978
0.00741*-0.1017
-0.000753597
What is -2.2373 times -6.629?
14.8310617
What is -7.8500278 times 7?
-54.9501946
Work out 0.01950994 * -2.
-0.03901988
425428*1.81
770024.68
Multiply -69 and -352787.
24342303
1242*-6187
-7684254
-0.261 times -1423092
371427.012
85.561 times -9.2
-787.1612
Product of -131986 and 486.
-64145196
0.0346 * -22.054
-0.7630684
29174741 * -5
-145873705
Work out 46108.136 * -0.2.
-9221.6272
Calculate -57*-0.2017316.
11.4987012
0.01 * -5047.8478
-50.478478
180*-47.213
-8498.34
-976826.51 times 2
-1953653.02
-0.23060689 times 2
-0.46121378
Calculate 2*-118214.1.
-236428.2
Calculate -67089785*2.
-134179570
6 times 332727165
1996362990
-4 times -5419552
21678208
What is -3450.7 times -9?
31056.3
Product of 218 and -789.13.
-172030.34
-3308585 * 5
-16542925
0.03*2435368
73061.04
-1.9157*1459.2
-2795.38944
-36526*0.08434
-3080.60284
1264 * -16485
-20837040
Work out 71430900 * -0.3.
-21429270
Multiply -25921 and -1735.
44972935
Multiply -55190.48 and -16.
883047.68
Multiply 2.383 and 16394.
39066.902
Multiply -5778424 and 1.1.
-6356266.4
Product of 19236234 and 0.5.
9618117
Calculate 0*-10791986.
0
Multiply -1064 and -8165.
8687560
-2.569 * 8501
-21839.069
Product of 0.15 and -3109.64.
-466.446
Calculate -1515.8*-15.3.
23191.74
6 * 0.1145077
0.6870462
-1041.5 * 492
-512418
What is the product of 31 and -0.79857?
-24.75567
Multiply -0.0252 and 12.0053.
-0.30253356
Multiply -13 and -2.5087.
32.6131
What is 0.105 times -1750031?
-183753.255
What is 1191190 times 6?
7147140
Product of 28647.69 and -3.
-85943.07
Product of -5327 and -21.78.
116022.06
What is 3.37 times -11.0503?
-37.239511
Work out 64028 * 14.
896392
Product of -0.00684971 and 36.
-0.24658956
Calculate -179.66919*-0.13.
23.3569947
-25946 * -2474
64190404
Work out 0.00411559 * -0.3.
-0.001234677
Multiply -75976 and -1.7.
129159.2
Calculate -3207087*0.6.
-1924252.2
3090990*-0.2
-618198
0 times -116874609
0
-3829332 * -25
95733300
What is -1246100 times -0.008?
9968.8
Calculate -11.6434*2438.
-28386.6092
Multiply -0.07 and -1405.02.
98.3514
What is the product of -13033504 and 2?
-26067008
-3874654.5 times -3
11623963.5
What is the product of -9408 and 2.4?
-22579.2
Calculate 5*-15328771.
-76643855
What is 0.584 times 396522?
231568.848
Work out -0.4 * -13242009.
5296803.6
Calculate 1.509*32.635.
49.246215
-346 * 225668
-78081128
Multiply -7.3801 and -37.
273.0637
Product of 0.3 and -94.49909.
-28.349727
9.13 times 32.14
293.4382
Product of 1 and 156483645.
156483645
Multiply 37917.984 and 0.
0
0.53444 times 13
6.94772
-951543*-1
951543
368*65470
24092960
What is the product of -2343.4 and -325?
761605
122*15.3762
1875.8964
What is the product of 16861 and -3.174?
-53516.814
What is -56073103 times -2?
112146206
0.1 * 13560188
1356018.8
What is the product of -11 and -352.3253?
3875.5783
Multiply 1 and -78594490.
-78594490
38 times 1.283664
48.779232
Work out 0 * -119255.227.
0
5222510.4 times -0.1
-522251.04
Work out -9294 * 1543.
-14340642
Work out -0.1 * -9102970.
910297
Multiply -1.5 and 53.81156.
-80.71734
72653 times 30.61
2223908.33
Work out -1366286 * 71.
-97006306
Work out 0.1 * 1808618.38.
180861.838
What is the product of 0.3 and -8.254816?
-2.4764448
-699484*-1
699484
Multiply -0.23 and 20891.2.
-4804.976
Calculate -9.76534*0.5.
-4.88267
Multiply 21.38679 and 7.
149.70753
Product of -2.832 and 159.81.
-452.58192
Work out -0.14 * 0.0249139.
-0.003487946
What is -44617 times 0.0415?
-1851.6055
Calculate 2321416*-0.2.
-464283.2
What is th | 2024-02-01T01:26:59.872264 | https://example.com/article/6347 |
Here's the Deadpool shop animation if you didn't get it: pic.twitter.com/3mtbVxyAN4 | 2024-04-19T01:26:59.872264 | https://example.com/article/9609 |
<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE plist PUBLIC "-//Apple Computer//DTD PLIST 1.0//EN" "http://www.apple.com/DTDs/PropertyList-1.0.dtd">
<plist version="1.0">
<dict>
<key>IBDocumentLocation</key>
<string>208 27 356 240 0 0 1920 1178 </string>
<key>IBFramework Version</key>
<string>446.1</string>
<key>IBOpenObjects</key>
<array>
<integer>5</integer>
</array>
<key>IBSystem Version</key>
<string>8P135</string>
</dict>
</plist>
| 2023-11-24T01:26:59.872264 | https://example.com/article/9629 |
Dwayne "The Rock" Johnson Sells His Hidden Hills Mansion For $4.9 Million
According to TMZ, Dwayne "The Rock" Johnson has sold his stunning Hidden Hills mansion, and he nearly got it for the $4.9 million asking price. Located 22 miles from Hollywood, the 9,120-square-foot home features six bedrooms, seven bathrooms, an infinity pool, and one hell of a home theater. | 2024-07-20T01:26:59.872264 | https://example.com/article/7494 |
/* ************************************************************************
Copyright:
License:
Authors:
************************************************************************ */
/**
* This class demonstrates how to define simulated interaction tests for your
* application. See the manual for details:
* {@link http://manual.qooxdoo.org/3.0/pages/development/simulator.html}
*/
qx.Class.define("test.simulation.DemoSimulation", {
extend : simulator.unit.TestCase,
members :
{
/*
---------------------------------------------------------------------------
TESTS
---------------------------------------------------------------------------
*/
/** Check if a widget is present (part of the DOM) */
testButtonPresent : function()
{
this.assertNotNull(this.getSimulation().getWidgetOrNull("qxh=qx.ui.form.Button"), "Button widget not present!");
},
/** Click a button and check if an alert box pops up */
testButtonClick : function()
{
this.getQxSelenium().qxClick("qxh=qx.ui.form.Button");
this.assertEquals("true", String(this.getQxSelenium().isAlertPresent()));
}
}
});
| 2024-03-03T01:26:59.872264 | https://example.com/article/4868 |
Saturday, May 27, 2017
Back To United Van Lines -- May 27, 2017
Connecticut's population is falling: Its net domestic out-migration was nearly 30,000 from 2015 to 2016. In 2016, it lost slightly more than 8,000 people, leaving its population at 3.6 million.
Indeed, recent national moving company surveys underscore the trend, showing more people leaving Connecticut than moving in. In 2016, the state also saw a population decline for the third consecutive year.
One of the companies, United Van Lines, reported that of all their Connecticut customers, 60 percent were leaving compared to 40 percent who were moving there. Only three other states had higher rates of people moving out – New York, New Jersey and Illinois. One out of five of those leaving said they were retiring.
But solutions are in the works:
Some state legislators suggest legalizing marijuana as a new tax source, as well as new tolls and a new casino. Other legislators and economic analysts say one remedy is to start taxing services, such as dog grooming. | 2024-07-03T01:26:59.872264 | https://example.com/article/4664 |
/* TyTools - public domain
Niels Martignène <niels.martignene@protonmail.com>
https://koromix.dev/tytools
This software is in the public domain. Where that dedication is not
recognized, you are granted a perpetual, irrevocable license to copy,
distribute, and modify this file as you see fit.
See the LICENSE file for more details. */
#ifndef TY_CLASS_PRIV_H
#define TY_CLASS_PRIV_H
#include "common.h"
#include "board.h"
#include "class.h"
#include "../libhs/match.h"
_HS_BEGIN_C
struct _ty_class_vtable {
int (*load_interface)(ty_board_interface *iface);
int (*update_board)(ty_board_interface *iface, ty_board *board, bool new_board);
unsigned int (*identify_models)(const struct ty_firmware *fw,
ty_model *rmodels, unsigned int max_models);
int (*open_interface)(ty_board_interface *iface);
void (*close_interface)(ty_board_interface *iface);
ssize_t (*serial_read)(ty_board_interface *iface, char *buf, size_t size, int timeout);
ssize_t (*serial_write)(ty_board_interface *iface, const char *buf, size_t size);
int (*upload)(ty_board_interface *iface, struct ty_firmware *fw,
ty_board_upload_progress_func *pf, void *udata);
int (*reset)(ty_board_interface *iface);
int (*reboot)(ty_board_interface *iface);
};
struct _ty_class {
const char *name;
const struct _ty_class_vtable *vtable;
};
extern const struct _ty_class _ty_classes[];
extern const unsigned int _ty_classes_count;
extern const hs_match_spec *_ty_class_match_specs;
extern unsigned int _ty_class_match_specs_count;
_HS_END_C
#endif
| 2023-10-11T01:26:59.872264 | https://example.com/article/6965 |
Mas from Latina
Search form
Star Tracker: Demi Lovato, Alejandro Sanz, and Bella Thorne
— The wedding between Kim Kardashian and Kris Humphries this weekend was nothing short of a star-studded affair. Among the invited guests were Desperate Housewives star Eva Longoria, Jennifer Lopez, Demi Lovato, and La La Anthony. Anthony spoke to us last week about her best friend’s wedding in an exclusive interview.
— According to TV Guide, the executive producer behind CBS’ NCIS is going all out for it’s 200th episode. “We came up with a unique, unexpected story to help us look back on everything prior,” Gary Glasberg said of the episode, which will premiere in early 2012. The drama series stars Chilean-born actress Coté de Pablo as Special Agent Ziva David. She was recently nominated for an ALMA Award for her role.
— Demi Lovato celebrated her 19th birthday a day early this year. The “Skyscraper” singer celebrated her special day on Friday with clothing designer Hanna Beth in Hollywood. Perez Hilton reports that no alcohol was present at the party, but the venue did have an open Red Bull bar. Lovato spent her real birthday at Kim Kardashian’s wedding. Over the weekend, Lovato also took to Twitter to reveal the cover art of her new album, Unbroken. Can we say stunning?
— Felipe Calderon, Mexico’s president, will star in a PBSadventure show. According to Huffington Post, the 49-year-old Mexican leader will serve as a sort of tour guide in a series of 30-minute programs. Accompanied by Peter Greenberg, host of the "The Royal Tour" TV series, Calderon will don an Indiana Jones-style hat and wander into the Golondrinas cave, among other adevntures. According to Tourism Department spokesman Roberto Martinez, the leader’s involvement is part of his strategy to promote Mexico abroad.
— Disney has announced that it will debut the second season of its hit dance comedy “Shake It Up” on Sunday, Sept. 18. The show stars part Cuban Bella Thorne and Cuban Adam Irigoyen. | 2023-08-07T01:26:59.872264 | https://example.com/article/9832 |
Richard Matthews (soldier)
General Richard Matthews (d. 1783) was a soldier who fought with the Army of the East India Company. He fought in the Second Anglo-Mysore War (1780-84).
Bednore
After initial successes in seizing the forts of Rajamundroog and Mirjan (Merjee) before moving on and taling Honnavar (Onore). Matthews was ordered to advance on Bednore. Following the death of Hyder Ali, the commander of Bednore, Hyat Sahib, the Mysore commander had learnt that Tipu Sultan intended to remove him from command, surrendered to Matthews.
References
Category:1783 deaths | 2024-03-15T01:26:59.872264 | https://example.com/article/9240 |
A look back: WRAL covers War in Iraq, 2003
You must enter the characters with black color that stand out from the other characters
It's been 10 years since a U.S.-led coalition attacked Iraq, leading to the fall of Saddam Hussein. WRAL News anchor/reporter Ken Smith was in Kuwait and Iraq in the early days of the conflict. Here's a look back at those reports. | 2024-07-20T01:26:59.872264 | https://example.com/article/8263 |
Amino acids which cause excitatory pastsynaptic potential are called as excitatory amino acids (EAA) and such acidic amino acids as L-glutamate, L-aspartate, L-homocysteine acid and quinolinic acid are known as internal substances. It is presumed that neurons using the said amino acids as the transmitters play the central role in the excitatory neurons of the mammalian brain. As a result of the recent rapid progress of the active researches conducted on the mechanism of the EAA transmission the relationship between a wide range of functions of the brain and the disorders of the brain is being unraveled. It has been found that in medicaments causing the disorders very similar to schizophrenia is there is a medical substance which intercepts the actions of the EAA receptors of the type of NMDA(N-methyl-D-aspartate). Accordingly strong attentions have been drawn on a probable participation of the disorders of the EAA transmission in schizophrenia.
As mentioned above the L-glutamate or the L-aspartate, which are amino acids, is a neurotransmitter causing the primary excitotoxic action in the central nervous system. By a number of researches it has been unraveled that the above-mentioned excitatory amino acid relates to a wide range of neurophysiological functions including synaptic transmission, the regulation and the long-term potentiation of neurotransmitters, learning and memory, the flexibility of synaptic generation, ischemic hypoxic disorders and neuronal death, and the cause of several neurodegenerative disorders.
For example, in Alzheimer's or cerebrovascular dementia distinguishing primarily the deterioration of the brain actions the deterioration of glutamatergic transmission is considered to be the cause, and also, the disorder of the glutamatergic transmission is found in schizophrenia.
Glutamate receptors which exist locally in synaps have been classified into the followings according to the receptor's affinity with specific ligand and electrophysiological or neurochemistric actions.
The NMDA (N-methyl-D-aspartate) receptor related to an ion channel characterizing the penetrability of monovalent and divalent cations such as sodium ions and calcium ions and the blockade of magnesium ions.
The AMPA (.alpha.-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid) receptor related to an ion channel characterizing the penetrability of monovalent cations such as sodium.
The KA (kainate) receptor which is similar to the AMPA receptor in the ion characteristics but different from the AMPA receptor in both the conductance and the level of desensitization.
(The AMPA receptor and the KA receptor are sometime called collectively as the non-NMDA receptor.)
It is useful to develop potentiating substances of glutamatergic transmission to be used for the prophylactic and medical treatment of the neurodegenerative disorders in the said state of diseases. | 2023-11-01T01:26:59.872264 | https://example.com/article/3764 |
Article content
Drake Batherson is being given every opportunity to make the Senators.
Saturday night was no different as he skated on a line with centre Jean-Gabriel Pageau and winger Anthony Duclair as the Senators faced the Montreal Canadiens in their final pre-season home game at the Canadian Tire Centre.
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The key for the 21-year-old Batherson is to reach up and grab the job before the final cuts are made next Sunday morning. He has the chance to be on the opening night roster against the Toronto Maple Leafs, and coach D.J. Smith is confident that Batherson can help the club score goals this season if he’s able to stick here.
“Drake does a lot of things. He’s a lot bigger guy on the ice than you see from up top and he really moves a lot quicker, too,” Smith said Saturday morning. “He’s a big guy that I think is going to be able get to net fronts and loose pucks, he’s heavy. I like a lot of the parts of his game.
“The stats weren’t great in the rookie tournament, they were just OK, but I see this guy being able to score some goals and being able to be a real power forward in this league.”
bgarrioch@postmedia.com
Twitter: @sungarrioch
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‘We’ve got to be ready to play big minutes’: Chabot eager to develop partnership with Zaitsev | 2023-08-16T01:26:59.872264 | https://example.com/article/5564 |
Today Jeffrey Langdon (@jlangdon) posed on #SQLHelp the following questions:
So I set to answer his question, and I said to myself: “Hey, I haven’t blogged in a while, how about I blog about this particular topic?”. Thus, this post was born.
(If you have never heard of Ghost Records and/or the Ghost Cleanup Task, go see this blog post by Paul Randal)
1) Do ghost records get copied over in a backup?
If you guessed yes, you guessed right. The backup process in SQL Server takes all data as it is on disk – it doesn’t crack the pages open to selectively pick which slots have actual data and which ones do not. The whole page is backed up, regardless of its contents.
Even if ghost cleanup has run and processed the ghost records, the slots are not overwritten immediately, but rather until another DML operation comes along and uses them.
As a matter of fact, all of the allocated space for a database will be included in a full backup.
So, this poses a bit of a security/compliance problem for some of you DBA folk: if you want to take a full backup of a database after you’ve purged sensitive data, you should rebuild all of your indexes (with FILLFACTOR set to 100%). But the empty space on your data file(s) might still contain sensitive data! A SHRINKFILE might help get rid of that (not so) empty space, but that might not be the end of your troubles. You might _STILL_ have (not so) empty space on your files!
One approach that you can follow is to export all of the data on your database to another SQL Server instance that does NOT have Instant File Initialization enabled. This can be a tedious and time-consuming process, though. So you have to weigh in your options and see what makes sense for you. Snapshot Replication is another idea that comes to mind.
2) Does Compression get rid of ghost records (2008)?
The answer to this is no. The Ghost Records/Ghost Cleanup Task mechanism is alive and well on compressed tables and indexes. You can prove this running a simple script: | 2024-04-30T01:26:59.872264 | https://example.com/article/6551 |
// Licensed under the Apache License, Version 2.0 (the “License”); you may not
// use this file except in compliance with the License. You may obtain a copy of
// the License at
//
// http://www.apache.org/licenses/LICENSE-2.0
//
// Unless required by applicable law or agreed to in writing, software
// distributed under the License is distributed on an “AS IS” BASIS, WITHOUT
// WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied. See the
// License for the specific language governing permissions and limitations under
// the License.
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foreground: rgba($light-blue-300, .7);
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foreground: rgba($orange-200, .7);
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| 2024-03-01T01:26:59.872264 | https://example.com/article/6510 |
# Schema
## blocks.csv
Column | Type |
------------------|--------------------|
number | bigint |
hash | hex_string |
parent_hash | hex_string |
nonce | hex_string |
sha3_uncles | hex_string |
logs_bloom | hex_string |
transactions_root | hex_string |
state_root | hex_string |
receipts_root | hex_string |
miner | address |
difficulty | numeric |
total_difficulty | numeric |
size | bigint |
extra_data | hex_string |
gas_limit | bigint |
gas_used | bigint |
timestamp | bigint |
transaction_count | bigint |
---
## transactions.csv
Column | Type |
-----------------|-------------|
hash | hex_string |
nonce | bigint |
block_hash | hex_string |
block_number | bigint |
transaction_index| bigint |
from_address | address |
to_address | address |
value | numeric |
gas | bigint |
gas_price | bigint |
input | hex_string |
block_timestamp | bigint |
---
## token_transfers.csv
Column | Type |
--------------------|-------------|
token_address | address |
from_address | address |
to_address | address |
value | numeric |
transaction_hash | hex_string |
log_index | bigint |
block_number | bigint |
---
## receipts.csv
Column | Type |
-----------------------------|-------------|
transaction_hash | hex_string |
transaction_index | bigint |
block_hash | hex_string |
block_number | bigint |
cumulative_gas_used | bigint |
gas_used | bigint |
contract_address | address |
root | hex_string |
status | bigint |
---
## logs.csv
Column | Type |
-------------------------|-------------|
log_index | bigint |
transaction_hash | hex_string |
transaction_index | bigint |
block_hash | hex_string |
block_number | bigint |
address | address |
data | hex_string |
topics | string |
---
## contracts.csv
Column | Type |
-----------------------------|-------------|
address | address |
bytecode | hex_string |
function_sighashes | string |
is_erc20 | boolean |
is_erc721 | boolean |
block_number | bigint |
---
## tokens.csv
Column | Type |
-----------------------------|-------------|
address | address |
symbol | string |
name | string |
decimals | bigint |
total_supply | numeric |
---
## traces.csv
Column | Type |
-----------------------------|-------------|
block_number | bigint |
transaction_hash | hex_string |
transaction_index | bigint |
from_address | address |
to_address | address |
value | numeric |
input | hex_string |
output | hex_string |
trace_type | string |
call_type | string |
reward_type | string |
gas | bigint |
gas_used | bigint |
subtraces | bigint |
trace_address | string |
error | string |
status | bigint |
trace_id | string |
### Differences between geth and parity traces.csv
- `to_address` field differs for `callcode` trace (geth seems to return correct value, as parity value of `to_address` is same as `to_address` of parent call);
- geth output doesn't have `reward` traces;
- geth output doesn't have `to_address`, `from_address`, `value` for `suicide` traces;
- `error` field contains human readable error message, which might differ in geth/parity output;
- geth output doesn't have `transaction_hash`;
- `gas_used` is 0 on traces with error in geth, empty in parity;
- zero output of subcalls is `0x000...` in geth, `0x` in parity;
You can find column descriptions in [https://github.com/medvedev1088/ethereum-etl-airflow](https://github.com/medvedev1088/ethereum-etl-airflow/tree/master/dags/resources/stages/raw/schemas)
Note: for the `address` type all hex characters are lower-cased.
`boolean` type can have 2 values: `True` or `False`. | 2024-03-11T01:26:59.872264 | https://example.com/article/5916 |
In a UMTS (Universal Mobile Telecommunications System) network, attempts are made to optimize features of the system, which are based on W-CDMA (Wideband Code Division Multiple Access), by adopting HSDPA (High Speed Downlink Packet Access) and HSUPA (High Speed Uplink Packet Access), for the purposes of improving spectral efficiency and improving the data rates. With this UMTS network, long-term evolution (LTE) is under study for the purposes of further increasing high-speed data rates, providing low delay, and so on (non-patent literature 1).
In a third-generation system, it is possible to achieve a transmission rate of maximum approximately 2 Mbps on the downlink by using a fixed band of approximately 5 MHz. Meanwhile, in a system of the LTE scheme, it is possible to achieve a transmission rate of about maximum 300 Mbps on the downlink and about 75 Mbps on the uplink by using a variable band which ranges from 1.4 MHz to 20 MHz. Furthermore, with the UMTS network, successor systems of LTE are also under study, for the purpose of achieving further broadbandization and higher speed (for example, LTE-advanced (“LTE-A”)). | 2024-03-20T01:26:59.872264 | https://example.com/article/5392 |
Q:
Elastic Search JDBC River Plugin SQL Server Integrated Security
So I've been working on implementing elastic search using the JDBC River plugin to get data from our SQL Server DB into elastic search.
I've got it working fine using the SQL Server credentials, but trying to use integrated security doesn't work. It will create the index, but it doesn't have data in it.
The parameters I've been using are:
PUT /_river/test_river/_meta
{
"type":"jdbc",
"jdbc":
{
"driver":"com.microsoft.sqlserver.jdbc.SQLServerDriver",
"url":"jdbc:sqlserver://testServer:1433;databaseName=TestDb;
integratedSecurity=true;",
"user":"",
"password":"",
"sql": "select * from users",
"poll":"30s",
"index":"testindex",
"type":"testusers"
}
}
I've tried quite a few things, including removing the user and password fields completely, removing integratedSecurity=true, but it gave the same result.
I've checked on their github for the river plugin and it says this issue was fixed back in January, but it still doesn't seem to be working.
Also I'm using elastic search version: 1.5.1
and jdbc river plugin version : 1.4.0.10
Any help would be much appreciated
A:
Get rid of the user and password options. You're not gonna need them.
Check the console when running elasticserch.bat, you should see an error message when it tries to update the river. I'm going to go out on a limb and assume you're probably seeing an error stating that the file sqljdbc_auth.dll can't be found. If this is the case, you can download this file from here and copy the x64 version of sqljdbc_auth.dll to your java lib folder. For me, this folder is C:\ProgramData\Oracle\Java\javapath but you can type echo %path% in a console window to find yours.
Once you have followed these steps, restart elasticsearch.bat, and it should start processing your river. If not, post back with the output you're seeing when running elasticsearch.bat.
| 2023-08-27T01:26:59.872264 | https://example.com/article/6266 |
31 July, 2019
When the Good Night Beckons
I've long felt a kind of distant, undeserved kinship with Renaud Lavillenie. We're within 5 months of the same age. We're both pole vaulters, and we both started over 20 years ago.
He's much better, obviously. But whenever someone's questioned me about the realities of pole vaulting at our age, I would point out Renaud as a canonical example of what's possible. "The world record holder is still competing, and we're the same age," I would retort. If he can keep going at his level, then I can keep going at mine.
Even so, I've been struggling with injuries for a number of years at this point. But with each passing season, I learn something new; I take the time to recover; and I come back a little bit more prepared. And as those years have progressed, Lavillenie was always my beacon — an existence proof that I could still get a good season once I found the right balance of training, rest, and dedication.
So it was unnerving when, two seasons ago, his fate took a turn towards my own. Chronic upper leg issues caused an early end to his season. And then after a very promising 2018, another upper-leg injury put his 2019 season on pause when it had only just begun.
Lavillenie skipped his indoor season and a number of outdoor competitions, and this meet, the Prefontaine Classic, would be his second outdoor competition of the year. In interviews reported by AFP, Renaud said he wanted to use this meet to prove that he was back on a trajectory to be competitive for the French championships and World championships.
There are many cruelties in track and field, but two in particular feel especially bitter. First, your failures are often public. Everyone knows your story. Everyone can compare your performance now against the performances you used to accomplish. So when you fall short, that suffering is clear for everyone to see. And those feelings are often compounded by the sense of public exposure.
The second is that your body will eventually fail you. You will eventually make the transition from "I just need to adjust my training," to "maybe there's not much I can do about this."
That loss of agency is heartbreaking.
That betrayal is in the cards for everyone, but it's still a shock when it happens. It's even more of a shock when it starts to seem like a habit. A pattern. When your best efforts are about preserving what you had yesterday, rather than building toward a better tomorrow.
So it was unnerving, again, when I watched Renaud compete at the Prefontaine Classic. His entire demeanor exuded frustration. His body language after a second-attempt miss at 5.61m seemed to whisper, "I give up."
As he lay on the pit after that attempt, it reminded me of innumerable tortured souls in paintings of old, turning away as they realize that they're living out a nightmare. Pole vault is always bittersweet, but in this moment, the sweetness seemed completely absent.
Sometimes the simplest questions in life are the most painful: do you stop, or do you keep struggling? Do you accept what is, in many ways, unavoidable?
Loved it? Help me to help you! You deserve quality, and quality takes time.When you pledge $1 per post via Patreon, it helps me to make time to write, and also helps me with equipment maintenance and event fees. 100% of proceeds are reinvested in my photography: properly-functioning equipment enables me to produce my best work, and having a closer connection with my fans motivates me to put in the time that high-quality work requires. Help me to help you. | 2024-02-09T01:26:59.872264 | https://example.com/article/5219 |
Q:
Stop Node server in terminal and return to file in vim
I am new to Node and vim.
I have the following code file, server.js open in vim:
var http = require("http");
function onRequest(request, response) {
console.log("Request received");
response.writeHead(200, {"Content-Type": "text/plain"});
response.write("Hello World");
response.end();
}
http.createServer(onRequest).listen(8888);
console.log("Server has started");
When I enter vim "command" mode and type:
:!node server.js
Things work as expected (I think). The window changes to the standard terminal window, and if I open a browser and navigate to localhost on port 8888, the silly "Hello World" text is displayed.
The terminal displays the "Server has started" text, and the output that the request was received. All is well.
When I close the browser window, and type Ctrl-z to stop the Node server, the terminal displays [1}+ stopped vim server.js, but does not return me to my code file in vim.
If I return to vim by typing vim, vim opens into the same directory, but my file is not open. If I try to open the file, vim complains about a duplicate swap file. Obviously I can use the [R]ecover option, but it seems like I am missing a step.
What am I missing here?
I have googled, and searched SO, but I am not sure what I am asking for beyond the title of this question (which has not produced the answer I am looking for, or if it did, I didn;t recognize it). I am just new enough that I am unsure if I am missing something about the terminal, or vim, or *nix.
Thanks in advance . . .
UPDATE: It occurs to me I never clearly state what I am after - I am wanting to stop the server in the terminal and return to the open file in vim. As Tadman mentions below, I knew I was probably attempting to open an additional editor instance. What I was unclear on was how to return to the existing instance. Trying Tadman's suggestion now.
A:
You're creating a sub-shell to run node, suspending that with ^Z and then open a new copy of vim when you do your next step. Now you have two editors running, so you get an error about the swap file.
Why not either do this in a separate shell, which is what most people tend to do, or use ^C to stop the server and return to your editor?
| 2024-03-29T01:26:59.872264 | https://example.com/article/4848 |
Or You Could Organize a Flash Mob
“I don’t know why they even make the kids go to school during the last 2 weeks. The textbooks have been picked up, grades turned in, and all the teachers do is show movies.” Okay, first of all – NOT TRUE! Okay, maybe some of it is sometimes true. Possibly.
But think about it. Let’s say school ended in March instead of June. Wouldn’t we still have the same problems? As far as I can see, the only solutions are:
A.) Make the end date of school a surprise every year by having a groundhog predict it with his shadow:
“Hooray! He saw his shadow. That means six more weeks until we can ask him to come out again and repeat this process.”
“Oh darn! He didn’t see his shadow! That means today is your last day of school!”
OR
2.) Schedule all standardized for the last 2 days of school. Because, let’s face it, that’s the only thing that gives school meaning. Otherwise, it’s just about learning for the sake of learning.
Granted, neither of those solutions would be very popular. So, I think we have to go with Door #3 and make the last two weeks as meaningful as possible – maybe even more meaningful. What can we do to make ourselves, as teachers, feel less like babysitters?
Give our students some physical activity by teaching them how to pack up a classroom. Give our students some physical activity with GoNoodle or Deskercises.
Assign them to draw whatever they want, which usually results in Minecraft, Pokemon, or My Little Pony posters they all want to gift you with. Assign them to draw something that challenges them to think, like a S.C.A.M.P.E.R. picture or a Sketch Note that summarizes their year.
Speaking of boxes, you probably need to pack some – so get those young, energetic kids to load them up for you. Speaking of boxes, you can always have the students bring in their own, and design games to play the last day of school (on which they will be sure to bring those games home). Even better, put all the stuff you don’t need anymore into a pile and challenge them to make something new using only those supplies (with the understanding that their new invention will definitely go home with them on the last day).
I think I’ve suggested enough ideas to last one or two days. How about we crowdsource activities for the other 7 or 8 days? Put your favorite end-of-year lessons in the comments below! | 2023-09-06T01:26:59.872264 | https://example.com/article/6849 |
[Ki-1-positive anaplastic large-cell lymphoma with mediastinal involvement].
A 30-year-old woman was admitted to our hospital because of an abnormal mass shadow in the right side of the mediastinum on a a chest X-ray film. The chest X-ray film and computed tomogram revealed a mass approximately 4.8 cm in diameter in the right side of the mediastinum. The mass had invaded the right supraclavicular fossa. Lymph-node biopsy was done. Microscopical examination of an HE-stained specimen of a supraclavicular lymph nodes showed prediferation of large atypical lymphocytes. These atypical lymphocytes were stained immunohistochemically with anti-Ki-1 antibody. No T cell or B cell markers were found on these cells. No other tumors were detected by radiological examination. Therefore, our diagnosis was anaplastic large-cell lymphoma, which is identical to Ki-1 lymphoma of the mediastinum. | 2023-12-06T01:26:59.872264 | https://example.com/article/5729 |
By John Reiner Antiquerra
THE PRESIDENT has made it well known that he is no fan of the press, but what about the Filipino public?
Judging from the posts on PCIJ’s “Shout Out for Press Freedom” wall at the recent Alinday Advocacy Fair at the...
THE PHILIPPINE CENTER FOR INVESTIGATIVE JOURNALISM (PCIJ) announced today the launch of The PCIJ Story Project, a new initiative that will provide grants of P15,000 up to P75,000 to journalists and artists who work together to produce innovative...
STATEMENT OF THE RIGHT TO KNOW, RIGHT NOW! COALITION
THE ISSUANCE on July 23, 2016 of Executive Order No. 2 on Freedom of Information drew support from the Right to Know, Right Now! Coalition as a signal of the commitment of the Duterte Administration...
By Karol Ilagan
UNITED FOR THE ENVIRONMENT. Students and environmental activists held placards with calls for change in environment policies addressed to President Rodrigo R. Duterte. Photo by Karol Ilagan/PCIJ
FRANCES Quimpo’s recollection of...
By Malou Mangahas, Philippine Center for Investigative Journalism
First of Three Parts
TO THE LAST, they sing the same song: They hate corruption. They love the poor. They mean well. They are true. They are good. They are pure.
Or at least that...
By Titon Mitra*
AS WORLD LEADERS converge on Paris from 30 November to 11 December, the importance of arriving at an ambitious yet implementable agreement on climate change action has been graphically underlined by the fact that, based on UK Met Office...
TODAY starts a week-long job-application and registration process for those who aspire to lead the nation.
The applicants have only until Friday, Oct. 16, to file their certificates of candidacy with the Commission on Elections (Comelec).
In all,... | 2024-07-06T01:26:59.872264 | https://example.com/article/3055 |
Q:
How do I maximize my upper body workout from riding?
I often hear people say “your bike is a whole-body gym”. I know my upper body workout will never be close to the workout my legs get, but so long as I’m a bike commuter, I figure I ought to get as much as I can out of it. I have a Trek 8.3DS, flat handlebars, no bullhorns, no upright grips.
How do I adjust my riding style/choice of bike/choice of equipment/types of rides to maximize whatever upper body exercise biking can give me?
A:
The "pure" answer to the question as asked is probably as others have said, climb as much as possible. But perhaps a better answer is to admit that cycling is awesome for aerobic fitness and leg strength but not as great on the upper body.
Obviously, cross-training is an option, but even if you are 100% committed to your bike, you can probably get significant results from two common calisthenics pre and/or post ride: Push-ups and Pull-ups. The key is that you want to develop your chest/shoulders/triceps (pushing) and your back/biceps (pulling), and doing multi-joint exercises is likely more efficient/helpful than isolation exercises. If you can't do pull-ups and don't have access to a lat pulldown machine you can help yourself by using your legs to give yourself a gentle assist. If you have or can scrounge some dumbbells you can do a bit more.
Try this:
Do a set of 20-25 pushups, then 8-12 pull-ups, either just before or just after you put on your shorts/jersey.
Do a second set 5 minutes later after you've made up your water bottles, etc., put on your shoes, whatever.
Pump up your tires and get your bike "ready," then do a third set.
Go for a ride, and try to get in as much climbing as possible. You'll probably be amazed at how quickly your strength will improve just with three sets of good form concentrated upper body calisthenics pre-ride. Again, if you have dumbbells or a weight bench you could do bench presses/military presses, or laterals, and you could do rows to help with the "pull," but the goal isn't really do to a full on weightlifting session, just some quick calisthenics with one effective push and one effective pull exercise and at least two, preferably three sets as you prep for your ride.
A:
I think there are two important ways to use your upper body riding a bicycle:
Ride very steep hills, where you need to pull up the handlebar and swing your upper body to counteract the torque on the pedals (specially if you ride a bike without extra-low gears);
Riding over technical terrain, like XC mountain bike and other stuff.
While commuting, you can do these (or at least a bit of these) if you choose some unusual route if you live in a hilly area.
If that is not the case, I am afraid riding itself is not enough to provide significant upper-body exercise (except postural "exercise", which might indeed induce health issues if too prolongued).
Hope this helps
A:
There is a way to train your upper body while riding, but it's not the way most of people think of. Have you ever looked at pro BMXers arms? I rode BMX myself and can confirm that lots of bunnyhops, manuals and jumps are serious upper back, and whole arms workout. Just think of it, in a bunnyhop you pull with your lower and upper back, together with the arms, then you push using again your back and arms. But I don't know how this could go under common term of riding :-)
| 2024-03-09T01:26:59.872264 | https://example.com/article/1448 |
NEWARK —Essex County College graduated its largest-ever class Friday of 1,502 students, which included a young woman whose family has also been educated at the school.
College president Gale Gibson emphasized the college’s current success and potential in an interview before the ceremony at the Prudential Center.
“We have the largest number of STEM (Science Technology Engineering Math) students in this class," Gibson said. "We have 13 students with 4.0 GPAs and a number of students going to Ivy League institutions. I think that at this point in our history, we are poised to do great things.”
The college sends more of its graduates to Rutgers-Newark, New Jersey Institute of Technology and Montclair State University than any other two-year college in the state, ECC spokeswoman Yla Eason said in a news release. Due to its 46 percent black and 26 percent Hispanic population, the college is an official predominantly black institution and designated Hispanic-serving institution, Eason said.
“As always in urban education, we are concerned with our retention and graduation rates," Gibson said. "They are steadily increasing. We put a number of intentional interventions in place so that we can create greater student success, so I’m really pleased about that. “We have a number of certificate programs and with the new degree programs such as logistic supply management and cyber security, our students are prepared to go into the world and work.”
Sofia Medina, a member of the Class of 2014, was recognized during the ceremony as one of two Jack Kent Cooke scholars at ECC. She is a member of the honor society and earned an associate degree in biology/ premedicine. As part of the award, she will receive a transfer scholarship of $90,000 to study public health at Johns Hopkins University in Baltimore.
“For me, it’s a great milestone. When I started at ECC, it was a great opportunity. I didn’t have any other means because of my parents’ financial circumstances. So when I graduated from high school, it was very devastating because I thougth it wouldn’t enable me to get a higher education,” Medina said.
Medina’s parents and three brothers have all been educated at ECC. The Medina family immigrated from Ecuador when Sofia and her siblings were children and chose ECC because it was an affordable option for education.
“The college was a very good option and helped me be very efficient in my work. It gave me the confidence to start my own business,” said Sofia’s father, Jose Medina Sr.
Although Sofia’s father studied architecture in Ecuador, he had to learn English once arriving in the United States. He now runs a small architecture and design firm called Architechtonics in Bayonne.
Sofia’s mother, Sonia, said that “it was a blessing because [ECC] treats alums like family. It’s very personal. They give support, so it’s not just academic, it’s personal and human.”
Sonia also said she admires the school's strong alumni network. She said that after graduating, her sons still get together with other ECC alumni and give each other advice and support.
The oldest Medina son, Jose Jr., graduated ECC in 2006 as a Jack Kent Cooke scholar. After earning his bachelor's and master's degrees at the Georgia Institute of Technology, he now works for Black & Veach, an infrastructure firm headquartered in Kansas.
Another brother, Sebastian, graduated ECC in 2011 and will soon attend Columbia University in New York City for his master's degree in architecture. Sofia’s brother Pedro studies music at ECC and her mother will soon study business there.
“We’re all very proud," Jose Jr. said of his siblings’ success. "When I was at Essex I was very motivated, and I owe that drive to my parents. I think my success was very much due to that but when I finished my schooling, each one of them in their own way went above and beyond. I thought I did well, but these kids just did amazing.” | 2024-01-02T01:26:59.872264 | https://example.com/article/7507 |
A central Queensland pistol club running shooting classes for people with an intellectual disability is hoping to find Australia's next Paralympic talent.
The Rockhampton Pistol Club runs the sessions every fortnight, and is regularly attended by up to half a dozen shooters with an intellectual handicap.
"They've improved out of sight, some would give our members a bit of a run for their money," club secretary Mike Ahern said.
"Fortunately pistol shooting is a sport where you don't need any great physical fitness to be good at it.
"It certainly is a sport where you can excel with any sort of physical or mental handicap."
Mr Ahern said some students were aiming to participate in the sport at a professional level. ( ABC News: Jonathan Hair )
A licensed club member watches over the shooters, and helps them improve with every shot.
The sessions have been taking place for 18 months, with one of the first challenges getting shooters to take it slow.
"We had a lot of trouble first go getting them to slow down, because it's a sport where you have a set procedure that you follow," Mr Ahern said.
"You have to constantly reinforce with them that it's, take your time, watch your sights, squeeze the trigger, follow through.
"I think it's good for them too, because they don't rush at it like they used to now."
Students set sights on professional level
Some of the shooters are now setting goals, like participating in the sport at a professional level or for Australia at the Paralympics.
"We have one particular gentlemen who, his goal is to get to the Paralympics in pistol shooting, and I think that needs to be encouraged," carer Jan Sayers said.
"It doesn't matter if you're able-bodied, or an intellectual impairment, or a physical disability you're able to accomplish whatever you want to accomplish."
Mr Ahern said seeing a shooter compete at that level would be great.
"We would really like to see something like that ... because it brings exposure to the sport," he said.
"People sort of think, pistol shooting, you're a wild sort of redneck, that blows away everything.
"They don't realise the skill and the discipline you've got to have to shoot a pistol accurately." | 2023-10-24T01:26:59.872264 | https://example.com/article/9997 |
She blamed pressures on the NHS and other Liverpool hospitals for the problem. She said: "It is many more than we would like, but it is just an indication of the general pressures on the system.
"Because we are a specialist trust, quite a lot of patients are referred to us from other hospitals, so strictly speaking they should go back to those hospitals when they have been treated.
"We have been finding it increasingly difficult to get them back because of the pressure the hospitals are under.
"We do keep them longer, so a lot are fit to go home at discharge but if we can't find intermediate care for them or social services support they do block beds.
"Non-availability of beds on wards and in intensive care does impact on operations."
Mrs Abendstern said the centre had put a bed utilisation project in place to try and halt bed blocking.
She said: "Some of it is about managing the patient journey better and being more efficient.
"For example, when patients come in for tests or minor procedures, instead of having them sitting in a hospital bed we have started getting them in on an outpatient basis.
"We have introduced a discharge lounge because we found patients were taking up bed space waiting for an ambulance or prescription before going home.
"We have also freed up beds by allowing neurophysiology patients, who need their brain patterns monitored, to take the equipment home instead of staying in hospital."
Battling bed blocking>
MORE than 11,400 patients blocked beds at Merseyside's four biggest hospital trusts last year.
They clogged up beds at the Royal Liverpool and Broadgreen University Hospitals Trust, Aintree Hospitals NHS Trust, Wirral Hospitals NHS Trust and St Helens and Knowsley Hospitals NHS Trust.
It meant that thousands of people due to undergo non-emergency surgery had their operations cancelled or postponed.
But hospital and social services bosses are quick to stress that the situation had greatly improved over the past few months.
At the Royal the average number of patients blocking beds each week almost halved from 61 per week in the first quarter of last year to 34 in the final quarter.
Worst in Merseyside was St Helens and Knowsley Hospitals NHS Trust, with an average of 3,536 delayed discharges over the year, reaching a peak of 91 in one week.
They were followed by 2,860 at Arrowe Park, 2,704 at the Royal and Broadgreen University Hospitals Trust and 2,392 at Aintree Hospitals NHS Trust.
The bed blocking has led to thousands of operations being cancelled in the region, although hospital chiefs today said it was impossible to put a figure on those postponed due to bed blocking alone.
At St Helens and Knowsley Hospitals NHS Trust, more than 1,083 operations were cancelled over the past 12 months, although bed blocking was not the only reason.
Veronica Jackson, assistant executive director of social services at Liverpool city council, said improvements had been made recently because they were working hard with hospitals to solve problems for the first time.
She said: "We are working very closely with hospitals to see how we can work smarter to make sure patients are assessed by an integrated team and the right package of care is put in place.
"This is the first time there has been a proper integrated approach and the first time we've really tried to make it work.
"We are reviewing existing systems and putting changes in place to make sure the system works. For example, one of the things we've done is put occupational therapy equipment in hospitals so it is on hand and there is no delay waiting for this when a patient needs to go home."
Mrs Jackson said an extra #900,000 from the government to tackle bed blocking had also helped.
She added: "Over the winter we were able to buy more care beds, put on extra social services staff over the holiday period and buy some more smaller bits of equipment.
"We also changed our two rehabilitation centres and increased the number of overnight beds and day care beds by 10 each."
All four hospital trusts said they would continue to work with social services to reduce bed blocking further next year. | 2024-03-09T01:26:59.872264 | https://example.com/article/6457 |
Short-term survival in renal transplantation from brain-death donors: focusing on recipients with diabetes background.
Our aim was to evaluate short term survival rates in renal transplant recipients from deceased donors, while focusing on recipients with diabetes mellitus background. This is a longitudinal follow-up study based on national registry of recipients in Ministry of Health and Medical Education in Iran from 2010-11. Five hundred fifty-five recipients, 226 (40.8%) females and 328 (59.2%) males, were included in the study. Mean (± SD) age of the recipients was 39 ± 14 years. Of donors 18.4% were females and 81.6% were males. Age of the donors was 33 ± 14 years. All allograft recipients from deceased donors enrolled in the study. Short-term graft survival (1 year) was determined. Data regarding age, gender, background disease and cold ischemic time of recipients and donors were collected from the organ procurement units. Allografts were functioning in 499 (90.1%) of recipients after one year. Of recipients 38 (6.9%) died and rejection of transplanted kidney occurred in 17 (3.1%) cases. So, in 55 (9.9%) cases, allografts were not functioning. There were significant relationships between short term graft survival of donors' gender, age of recipients, cold ischemic time and level of clearance of creatinine of recipients. In addition to cold ischemic time, graft survival can be affected by recipients' age. There are some other considerations and implications regarding the short term graft survival in renal transplantation from cadaver donors which are discussed in this paper. | 2023-11-05T01:26:59.872264 | https://example.com/article/3290 |
The visit of the defense ministers of Azerbaijan, Georgia and Turkey to Nakhchivan is continuing, the Defense Ministry of Azerbaijan told Trend Aug. 18.
Today, the defense ministers of Azerbaijan, Georgia and Turkey - Colonel-General Zakir Hasanov, Irakli Alasania and Ismet Yilmaz laid a wreath at the monument of Azerbaijan's national leader Heydar Aliyev in the center of Nakhchivan, and visited the Heydar Aliyev Museum.
The guests also visited the alley of martyrs and laid a wreath in the memory of the citizens who became martyrs for independence and territorial integrity of Azerbaijan.
Afterwards, the ministers visited a religious place called 'Ashabi-Kahf'. | 2024-03-06T01:26:59.872264 | https://example.com/article/3856 |
//===----------------------------------------------------------------------===//
//
// Part of the LLVM Project, under the Apache License v2.0 with LLVM Exceptions.
// See https://llvm.org/LICENSE.txt for license information.
// SPDX-License-Identifier: Apache-2.0 WITH LLVM-exception
//
//===----------------------------------------------------------------------===//
// UNSUPPORTED: c++03
// <filesystem>
// class directory_entry
// file_status status() const;
// file_status status(error_code const&) const noexcept;
#include "filesystem_include.h"
#include <type_traits>
#include <cassert>
#include "filesystem_test_helper.h"
#include "rapid-cxx-test.h"
#include "test_macros.h"
TEST_SUITE(directory_entry_status_testsuite)
TEST_CASE(test_basic) {
using namespace fs;
static_test_env static_env;
{
const fs::directory_entry e("foo");
std::error_code ec;
static_assert(std::is_same<decltype(e.status()), fs::file_status>::value, "");
static_assert(std::is_same<decltype(e.status(ec)), fs::file_status>::value, "");
static_assert(noexcept(e.status()) == false, "");
static_assert(noexcept(e.status(ec)) == true, "");
}
path TestCases[] = {static_env.File, static_env.Dir, static_env.SymlinkToFile,
static_env.DNE};
for (const auto& p : TestCases) {
const directory_entry e(p);
std::error_code pec = GetTestEC(), eec = GetTestEC(1);
file_status ps = fs::status(p, pec);
file_status es = e.status(eec);
TEST_CHECK(ps.type() == es.type());
TEST_CHECK(ps.permissions() == es.permissions());
TEST_CHECK(pec == eec);
}
for (const auto& p : TestCases) {
const directory_entry e(p);
file_status ps = fs::status(p);
file_status es = e.status();
TEST_CHECK(ps.type() == es.type());
TEST_CHECK(ps.permissions() == es.permissions());
}
}
TEST_SUITE_END()
| 2024-02-25T01:26:59.872264 | https://example.com/article/2619 |
A known problem which arises with such sprinklers, and in particular micro-sprinklers, whether these are of the rotary or of the static kind, is connected with the variation of output rate, spray range and distribution pattern as a consequence of variations in input pressure to the sprinkler, whether these arise as a result of variations in mains supply or as a result of variations in terrain which give rise to differing supply pressures reaching differing sprinklers.
In an attempt to overcome this particular problem, it has been known to associate the water supply to the sprinkler with suitable pressure or flow control means, by which it is desired to ensure that the water reaching the outlet nozzle of the sprinkler is always at a substantially constant outflow rate, irrespective of the supply pressure.
A further problem which arises is associated with sprinklers which are desired to operate at a relatively low output rate. Achieving such a relatively low output rate, and at the same time ensuring that the spray outflow is of sufficient velocity to ensure maintaining an adequate spray range, has involved the use of nozzles with increasingly smaller outflow apertures. It will be readily appreciated that the smaller the outflow aperture, the greater the danger that this aperture becomes blocked by grit and the like.
It is an object of the present invention to provide a new and improved irrigation sprinkler in which some or all of the above-referred-to disadvantages are significantly reduced. | 2024-04-28T01:26:59.872264 | https://example.com/article/1293 |
// <copyright file="TemplateTaggerTest.cs" company="Oleg Sych">
// Copyright © Oleg Sych. All Rights Reserved.
// </copyright>
namespace T4Toolbox.VisualStudio.Editor
{
using System;
using System.Diagnostics.CodeAnalysis;
using System.Linq;
using Microsoft.VisualStudio.Text;
using Microsoft.VisualStudio.Text.Tagging;
using Xunit;
public static class TemplateTaggerTest
{
[Fact]
public static void TemplateTaggerIsInternalAndNotIntendedForPublicConsumption()
{
Assert.True(typeof(TemplateTagger<ITag>).IsNotPublic);
}
[Fact]
public static void TemplateChangeCreatesNewTagSpans()
{
var buffer = new FakeTextBuffer(string.Empty);
var tagger = new TestableTemplateTagger(buffer);
bool tagsCreated = false;
tagger.CreateTagSpansMethod = snapshot => tagsCreated = true;
buffer.CurrentSnapshot = new FakeTextSnapshot(string.Empty);
Assert.True(tagsCreated);
}
[Fact]
public static void TemplateChangeRemovesOldTagSpans()
{
var buffer = new FakeTextBuffer(string.Empty);
var tagger = new TestableTemplateTagger(buffer);
tagger.CreateTagSpan(buffer.CurrentSnapshot.CreateTrackingSpan(new Span(), SpanTrackingMode.EdgeNegative), new ErrorTag());
buffer.CurrentSnapshot = new FakeTextSnapshot(string.Empty);
Assert.False(tagger.GetTaggedSpans(new SnapshotSpan(buffer.CurrentSnapshot, 0, buffer.CurrentSnapshot.Length)).Any());
}
[Fact]
public static void TemplateChangeRaisesTagsChangedEvent()
{
var buffer = new FakeTextBuffer(string.Empty);
var tagger = new TestableTemplateTagger(buffer);
tagger.CreateTagSpan(buffer.CurrentSnapshot.CreateTrackingSpan(new Span(), SpanTrackingMode.EdgeNegative), new ErrorTag());
bool tagsChangedEventRaised = false;
tagger.TagsChanged += (sender, args) => tagsChangedEventRaised = true;
buffer.CurrentSnapshot = new FakeTextSnapshot(string.Empty);
Assert.True(tagsChangedEventRaised);
}
[Fact]
public static void UpdateTagSpansCreatesNewTagSpans()
{
var buffer = new FakeTextBuffer(string.Empty);
var tagger = new TestableTemplateTagger(buffer);
bool tagsCreated = false;
tagger.CreateTagSpansMethod = snapshot => tagsCreated = true;
tagger.UpdateTagSpans(new TemplateAnalysis(null, null, null));
Assert.True(tagsCreated);
}
[Fact]
public static void UpdateTagSpansRemovesOldSpans()
{
var buffer = new FakeTextBuffer(string.Empty);
var tagger = new TestableTemplateTagger(buffer);
tagger.CreateTagSpan(buffer.CurrentSnapshot.CreateTrackingSpan(new Span(), SpanTrackingMode.EdgeNegative), new ErrorTag());
tagger.UpdateTagSpans(new TemplateAnalysis(null, null, null));
Assert.Equal(0, tagger.GetTags(new NormalizedSnapshotSpanCollection(new SnapshotSpan(buffer.CurrentSnapshot, 0, buffer.CurrentSnapshot.Length))).Count());
}
[Fact]
public static void UpdateTagSpansRaisesTagsChangedEventOnlyOnce()
{
var buffer = new FakeTextBuffer(string.Empty);
var tagger = new TestableTemplateTagger(buffer);
tagger.CreateTagSpansMethod = analysis =>
{
tagger.CreateTagSpan(analysis.TextSnapshot.CreateTrackingSpan(new Span(), SpanTrackingMode.EdgeNegative), new ErrorTag());
tagger.CreateTagSpan(analysis.TextSnapshot.CreateTrackingSpan(new Span(), SpanTrackingMode.EdgeNegative), new ErrorTag());
};
int tagsChangedEventCount = 0;
tagger.TagsChanged += (sender, args) => tagsChangedEventCount++;
tagger.UpdateTagSpans(new TemplateAnalysis(new FakeTextSnapshot(string.Empty), null, null));
Assert.Equal(1, tagsChangedEventCount);
}
[Fact, SuppressMessage("Microsoft.Reliability", "CA2001:AvoidCallingProblematicMethods", MessageId = "System.GC.Collect", Justification = "This is a test of garbage collection")]
public static void TemplateAnalyzerDoesNotPreventTemplateErrorTaggerFromGarbageCollection()
{
var buffer = new FakeTextBuffer(string.Empty);
var analyzer = TemplateAnalyzer.GetOrCreate(buffer);
var tagger = new WeakReference(new TestableTemplateTagger(buffer));
GC.Collect(2, GCCollectionMode.Forced);
GC.WaitForPendingFinalizers();
Assert.NotNull(analyzer);
Assert.False(tagger.IsAlive);
}
private class TestableTemplateTagger : TemplateTagger<ITag>
{
public TestableTemplateTagger(ITextBuffer buffer) : base(buffer)
{
}
public Action<TemplateAnalysis> CreateTagSpansMethod { get; set; }
public new void UpdateTagSpans(TemplateAnalysis analysis)
{
base.UpdateTagSpans(analysis);
}
protected override void CreateTagSpans(TemplateAnalysis analysis)
{
if (this.CreateTagSpansMethod != null)
{
this.CreateTagSpansMethod(analysis);
}
}
}
}
} | 2024-04-20T01:26:59.872264 | https://example.com/article/7436 |
Open source software is now the shortest route to bringing innovation to market. When through word of mouth millions of developers discover and download exciting new code under an open source license and put it to task, you can almost feel the world's technology baseline click up a notch. But does the profound effect of open source stop there?
For several years, GitHub, everyone's favorite cloud versioning and repository service, has argued that it does not. Recently, I moderated a panel at GitHub's offices where managers who worked at several enterprises agreed that the method used to develop open source code -- collaborative, self-organized, and distributed -- provides an attractive new model for developing enterprise software.
[ Also on InfoWorld: 10 JavaScript editors and IDEs put to the test | Download InfoWorld's Developers' Survival Guide for all the tips and trends programmers need to know. | Keep up with the latest developer news with InfoWorld's Developer World newsletter. ]
What does this model look like in practice? At a RedMonk conference a year and a half ago, Ryan Tomayko, who calls himself the first "developer employee" of GitHub, succinctly described the core idea:
Internally, our processes work very much like an open source project. There are projects, there are people interested in projects, there are people coming up with ideas for projects, they're submitting into projects, there are people reviewing those changes and either accepting or rejecting them.
In other words, radical simplicity -- especially compared to the complex processes most enterprise dev organizations employ. GitHub as an organization subscribes to the distributed, collaborative nature of open source and the healthy constraints it imposes. All communication must be electronic and public -- with open source, participants tend to be widely distributed -- so a kind of open audit trail of discussions is generated for reference and accountability. Everyone works asynchronously, so there are few dependencies and bottlenecks to circumvent.
The GitHub platform itself provides the open platform for this collaborative style. Actually, it's hard to overestimate the impact GitHub has had on accelerating software development in general, since it has made participation and collaboration vastly easier.
Back to the panel: All the participants had deployed the enterprise version of GitHub internally. Along with the platform, what happens when you apply the open source model inside an enterprise and enable people to choose the projects they want to work on or start projects on their own?
There was general agreement among the panelists that this was an exciting idea, although very much in the experimentation phase in practice. Dominick Tornow, director of engineering for SAP Labs, was especially bullish. Although he was quick to point out that conventional processes within SAP remained in place for production software, he was excited by the experimentation occurring with non-mission-critical projects. He also warned not to "underestimate the mindset shift to freedom and flexibility."
You can say that again. It's easy to ridicule an open, radically simple workflow when there are deadlines to meet. What if everyone wants to work on the fun projects and neglects the rest? How do you ensure developers meet security and compliance goals, particularly in light of the OpenSSL debacle? I have a feeling many enterprise development organizations would reject these ideas out of hand and double down on "agile" workflows that require a whiteboard the size of a wall to diagram.
So be it. But it's difficult to ignore the huge impact open source and GitHub are having on software innovation. At the Realtime Conference a year ago, Mikeal Rogers of Digital Ocean argued that the stunning success of Node.js has in large part been due to the fact that Node.js was one of the first major projects that assumed that GitHub was there, lowering the barrier to entry and enabling an ecosystem to explode around it.
The question remains: Can a democratized open source model work in the enterprise? Can it be grafted or melded into an existing enterprise development culture, or is a wholesale shift required? One thing for sure is that the sucess of open source innovation means the model can't be ignored. If you have experience grappling with this paradigmn shift, I'd love to hear about it.
This article, "The open source way of being," originally appeared at InfoWorld.com. Read more of Eric Knorr's Modernizing IT blog. And for the latest business technology news, follow InfoWorld on Twitter. | 2024-02-18T01:26:59.872264 | https://example.com/article/3107 |
AN AVID Les Dennis fan is distraught after his idol refused to let him name his pub the Les Dennis Lounge.
Jake Goldstein, 28, from Brighton, has just taken over The Globe pub in Middle Street, Brighton.
He had dreams of opening a “Les Dennis Lounge” given his obsession with the TV celebrity, and saw this as the perfect opportunity.
But according to Jake, Mr Dennis turned down the offer and refused to have the pub named after him.
Jake has now filmed himself delivering a heartfelt message to Les Dennis, telling him how he feels about the rejection, which he posted on the internet.
In the video he says: “Les Dennis let me down.
“Don’t get me wrong Les, I think you’re all right.
“I have followed you for years, your highs and lows, I feel like I was there with you, I feel like I understood you. But now Les, now I understand nothing.
“All I wanted was to open a lovely little bar in Brighton for all little Les Dennises in the world to play, but you had to ruin it, didn’t you, Les?
“When we called you up full of hope, can we open the Les Dennis Lounge, your name in lights Les, you seemed so into it.
“But then we got the call the next day – ‘my agent wouldn’t like it’. Be your own man Les. A whole pub in your honour, Les, but you turned it down, Les, you turned it down.”
Jake said Mr Dennis had been an idol of his for most of his life and described the celebrity, best known as the presenter for TV programme Family Fortunes , as “pretty sweet for a kid in the 90s”.
Despite the rejection, Jake is finding other ways to create enough of a Les Dennis atmosphere in his newly acquired pub.
He said there will be pictures of the actor and presenter on the walls.
He has also ordered Les Dennis masks for pubgoers to wear whether they like the celebrity or not.
He said pictures of other “old school” celebrities will decorate the pub to make sure Mr Dennis is not alone.
Jake said: “They may or may not like us having their pictures up.
“But it’s all tongue in cheek, essentially somewhere that’s really fun and a place for people who are up for a laugh.”
Jake, who has worked at bars in Brighton including the Plotting Parlour and Daddy Long Legs, has even created a “bittersweet” Les Dennis cocktail.
He said: “It’s made in honour of the man himself.
“When we spoke on the phone he said his agent wouldn’t like us naming it after him in case something bad happened at the bar which could reflect badly on him.
“We weren’t overly happy with his decision but very amicable.”
Jake has now decided to rename the pub Cease And Desist.
He said: “It will be like an American dive bar – lots of whisky and food which will be served until 1am and bands playing, a place for a good time.”
The pub opens on Friday.
Mr Dennis’s agent did not respond to The Argus’s repeated requests for a comment. | 2024-01-12T01:26:59.872264 | https://example.com/article/1518 |
George Don
George Don (29 April 1798 – 25 February 1856) was a Scottish botanist and plant collector.
Life and career
George Don was born at Doo Hillock, Forfar, Angus, Scotland on 29 April 1798 to Caroline Clementina Stuart and George Don, principal gardener of the Royal Botanic Garden Edinburgh in 1802. Don was the elder brother of David Don, also a botanist. He became foreman of the gardens at Chelsea in 1816. In 1821 he was sent to Brazil, the West Indies and Sierra Leone to collect specimens for the Royal Horticultural Society. Most of his discoveries were published by Joseph Sabine, although Don published several new species from Sierra Leone.
Don's main work was his four volume A General System of Gardening and Botany, published between 1832 and 1838 (often referred to as Gen. Hist., an abbreviation of the alternative title: A General History of the Dichlamydeous Plants). He revised the first supplement to Loudon's Encyclopaedia of Plants, and provided a Linnean arrangement to Loudon's Hortus Britannicus. He also wrote a monograph on the genus Allium (1832) and a review of Combretum. He died at Kensington, London, on 25 February 1856.
Legacy
The television gardener Monty Don is a great-nephew.
The plant species authored by George Don include:
Acacia cyclops G.DonCoastal Wattle
Acacia deltoidea G.Don
Acacia holosericea G.DonCandelbra Wattle
Acacia pendula A.Cunn. ex G.DonWeeping Myall, Boree
Acacia podalyriifolia G.Don
Acacia rigens G.DonNealie
Catharanthus roseus (L.) G.DonPink Periwinkle
Daviesia physodes G.Don
Isotoma scapigera (R.Br.) G.DonLong-scaped Isotome
Lagunaria patersonia (Andrews) G.Don
Ludwigia hyssopifolia (G.Don) Exell
Modiola caroliniana (L.) G.Don
Physochlaina orientalis (M.Bieb.) G.Don
Psittacanthus calyculatus (DC.) G.Don
Sagina maritima G.Don
Sphenotoma squarrosum (R.Br.) G.Don
Swainsona formosa (G.Don) Joy Thomps.
Viola pedatifida G.DonPrairie violet
The plant genera authored by George Don include:
Physochlaina G.Don
Selected publications
A general history of the dichlamydeous plants etc. by George Don in the Biodiversity Heritage Library
A general system of gardening and botany. Founded upon Miller's Gardener's dictionary, and arranged according to the natural system. 1831–1838
Biography of The Scottish Botanist George Don 1764-1814, His Life, Times, and Contemporaries, by Scottish Author Marilyn Reid, https://www.amazon.co.uk/Scottish-Botanist-George-Don-1764-1814/dp/1492192619
See also
List of Australian plant species authored by George Don
References
Bibliography
Category:Scottish botanists
Category:Scottish gardeners
Category:Scottish horticulturists
Category:1798 births
Category:1856 deaths
Category:Scottish garden writers
Category:Scottish encyclopedists
Category:Fellows of the Linnean Society of London
Category:Botanical collectors active in Australia
Category:Plant collectors
Category:People from Angus
Category:19th-century Scottish writers
Category:19th-century British botanists | 2024-01-28T01:26:59.872264 | https://example.com/article/2762 |
Acute normovolemic hemodilution for radical retropubic prostatectomy and radical cystectomy.
Radical retropubic prostatectomy (RRP) and radical cystectomy (RCx) are well tolerated and widely performed. Because intraoperative blood loss is one of the most common problems, we performed acute normovolemic hemodilution (ANH) to prevent allogenic blood transfusion (ABT). In this study we tried to clarify the safety, effectiveness and problems of ANH at urologic operations. The study included 169 patients who underwent RRP and 97 patients underwent RCx from April 2003 to March 2006. The eligible patients for ANH were required to have preoperative hemoglobin of 12 g/dL or more without history of myocardial ischemia. The amount of blood collected was 800 mL in RRP and 800 mL or 1200 mL in RCx. Neoadjuvant chemotherapy was performed in 11 (11.3%) of 97 patients with RCx. ANH was available in 164 (97.0%) of 169 patients in RRP and 41 (42.3%) of 97 patients in RCx. All 11 (11.3%) patients who received neoadjuvant chemotherapy before RCx revealed anemia and all were excluded from ANH. No patients had an hypovolemic event develop during the autologous blood being stored. The median volume of intraoperative blood loss was 1400 mL in 164 RRP and 19 patients (11.6%) required ABT. In 41 patients undergoing RCx, the median volume of blood loss was 1720 mL and 13 patients (32.5%) required ABT. In the postoperative period, no patients had cardiovascular or pulmonary complications develop originated from ANH. ANH is a safe and useful method of transfusion during RRP and RCx. ANH can be recommended for patients who need these operations. | 2024-01-31T01:26:59.872264 | https://example.com/article/7855 |
Q:
SQL counter variable @Count += 1
I would like to know if it's possible to create a Count variable like you would in C#.
DECLARE @Count Int
SET @Count = 0
--something happens
SET @Count += 1
--something happens
SET @Count += 1
IF @Count < 3
BEGIN
--Do something
END
A:
In SQL-Server you can do It in following:
SET @count = @count + 1
A:
In SQL Server 2008+ your code is perfectly valid:
DECLARE @Count INT;
SET @Count = 0;
PRINT @Count;
SET @Count += 1;
PRINT @Count;
SET @Count += 1;
IF @Count < 3
BEGIN
PRINT @Count;
END
LiveDemo
With version before 2008 you can use full syntax:
SET @Count = @Count + 1;
+= operator
Adds two numbers and sets a value to the result of the operation. For
example, if a variable @x equals 35, then @x += 2 takes the original
value of @x, add 2 and sets @x to that new value (37).
| 2024-03-11T01:26:59.872264 | https://example.com/article/8557 |
Q:
Is it dangerous to continue to remove a slightly punctured phone battery?
I have been trying to replace the phone screen on a Galaxy S7, and therefore had to remove the battery in the process. While doing so, I saw a tiny spark and felt a weird smell. I can't see any damage on the battery, but obviously it is no longer safe to use, and I am going to have to replace it, and dispose of the old battery properly. My problem is: the battery is still glued to my phone. Is it dangerous to continue to remove the battery now, or should I just trash the entire phone? If not; is it safe to use a heat gun to loosen up the glue?
Also; could it be dangerous to leave it on the kitchen table over night?
Should I wear gloves when doing this now?
I have looked for answers on the internet for over an hour now, but I still haven't found anything on removing an already damaged battery or the dangers of leaving it unattended.
A:
... had to remove the battery in the process.
While doing so, I saw a tiny spark and felt a weird smell. I can't see any damage on the battery, but obviously it is no longer safe to use, and I am going to have to replace it, and dispose of the old battery properly.
Given the above statements, your aims are removal of the battery without damage to
- yourself
- the phone
in that order.
Nothing is certain. You will probably be able to discharge the battery safely, but this is not 100% certain.
The phone's location during the removal process should be somewhere where a battery fire will not matter.
Discharging the battery fully, either using the phone or by other means, before attempting removal is safer than not doing so.
If you can turn the phone on then, as long as it is functioning normally, it will discharge the battery over the "standby period" or less.
If you can access the battery wires or terminals then you can discharge the battery using a resistor. This is a surer method but harder to do if inexperienced.
If it has a "flashlight" then this will usefully reduce discharge time.
The battery will still retain some energy when the phone decides that it is 'flat' but will be much less liable to cause damage.
(A 1500 mAh x 3.6V battery with 1% charge has about 150 Watt seconds of energy remaining. The same energy as is required to raise a 1 kg weight 15 metres - not to be treated too lightly).
... is it safe to use a heat gun to loosen up the glue?
Maybe, but not wise. Do not do unless essential AND you are willing to have the phone destroyed.
Even using the absolute minimum of temperature, the odds are the rise needed to be useful is above what the phone itself will withstand.
Also; could it be dangerous to leave it on the kitchen table over night?
Yes - potentially so. As above, leave phone somewhere that a fire does not matter (except to the phone).
Should I wear gloves when doing this now?
May help but adds fumble-fingeredness.
Probably good enough to use care, prompt action, eye protection, sensible clothes. LiIon batteries usually do not "explode" - they transition to a flaming heap - sometimes over a minute or so - or occasionally in seconds. I have NEVER had this happen but my all-care-no-responsibility comment is that I'd act as above with the awareness of the unlikely but possible worst case results.
Note the article cited by James Large in comments
Toxic fluoride gas emissions from lithium-ion battery fires. I'd be suitably wary of the fumes - but no more so than with fumes from many other electronic and chemical systems. ie aim to breath none, make it extremely unlikely that you'll get more than a whiff worst case, use of a fan or ventilator is liable to help. Note their notes on using water mist for extinguishing such fires. Water is not recommended as it reportedly may increase Lithium combustion rate and also the rate of HF production (but not the total HF produced).
| 2024-07-28T01:26:59.872264 | https://example.com/article/4006 |
Q:
how to stack two widgets and switch between them?
I want to script two widgets which would be stacked and I would switch from one to another with a key. Each widget would be a Frame containing several Labels. I have the following code so far (only one Label per Frame):
import Tkinter as tk
import ttk
import datetime
def main():
# initialize root
root = tk.Tk()
# initialize widgets
dash = Dashboard(root)
notepad = Notepad(root)
# set key actions
root.bind('<F11>', root.lift)
root.bind('<F1>', dash.raiseme)
root.bind('<F2>', notepad.raiseme)
root.mainloop()
class Dashboard(ttk.Frame):
def __init__(self, parent):
ttk.Frame.__init__(self, parent) # voodoo
self.dashframe = tk.Frame(parent)
self.labone = tk.Label(self.dashframe, text="lab1", fg='black', bg='blue')
self.labone.grid(row=0, column=0)
def raiseme(self, event):
print "raiseme dash"
self.labone.configure(text=datetime.datetime.now())
self.dashframe.lift()
class Notepad(ttk.Frame):
def __init__(self, parent):
ttk.Frame.__init__(self, parent) # also voodoo
self.noteframe = tk.Frame(parent)
self.laboneone = tk.Label(self.noteframe, text="lab11", fg='white', bg='red')
self.laboneone.grid(row=0, column=0)
def raiseme(self, event):
print "raiseme notepad"
self.laboneone.configure(text=datetime.datetime.now())
self.noteframe.lift()
if __name__ == '__main__':
main()
Pressing F1 and F2 reach the correct routines but the only thing I get is the main window, empty. There are no errors displayed so I guess that the code runs fine (just not the way O would like to :)).
Can I achieve the switch using the skeleton above?
A:
There are at least two big problems with your code.
First, you're creating all these new frames, but not placing them anywhere, so they will never show up anywhere. If you have a main window with nothing placed on it, of course you will just "get the main window, empty". You need to call pack or some other layout method on any widget to get it to show up on its parent. In this case, it sounds like you want to put them both in the exact same place, so grid or place is probably what you want.
Second, your Dashboard and Notepad classes are themselves Frames, but they don't do any Frame-ish stuff; instead, they each create another, sibling Frame and attach a label to that sibling. So, even if you packed the Dashboard and Notepad, they're just empty frame widgets, so that wouldn't do any good.
If you fix both of those, I think your code does what you want:
class Dashboard(ttk.Frame):
def __init__(self, parent):
ttk.Frame.__init__(self, parent) # voodoo
self.labone = tk.Label(self, text="lab1", fg='black', bg='blue')
self.labone.grid(row=0, column=0)
self.grid(row=0, column=0)
def raiseme(self, event):
print "raiseme dash"
self.labone.configure(text=datetime.datetime.now())
self.lift()
class Notepad(ttk.Frame):
def __init__(self, parent):
ttk.Frame.__init__(self, parent) # also voodoo
self.laboneone = tk.Label(self, text="lab11", fg='white', bg='red')
self.laboneone.grid(row=0, column=0)
self.grid(row=0, column=0)
def raiseme(self, event):
print "raiseme notepad"
self.laboneone.configure(text=datetime.datetime.now())
self.lift()
However, you might also want to set a fixed size for everything; otherwise you could end up lifting the red widget and, e.g., only covering 96% of the blue one because the current time is a bit narrower than the previous one…
The code you linked to for inspiration attempted to do this:
newFrame = tkinter.Frame(root).grid()
newFrame_name = tkinter.Label(newFrame, text="This is another frame").grid()
That won't work, because grid returns None, not the widget. But at least it calls grid; yours doesn't even do that.
| 2024-02-07T01:26:59.872264 | https://example.com/article/6513 |
Airbus
Manned electric-powered aircraft have made record-breaking flights and turned more than a few heads in the past few years, and it's not a trend that's likely to slow down. Last week, the E-Fan electric trainer airplane developed by the Airbus Group made its first public flight before a collection of French dignitaries. Currently a demonstrator for electric aircraft technology, Airbus says that is will be used as the basis for building a new pair of electric training aircraft models. Read More
Aeronautics giant Airbus has completed its project to recreate the surface of Mars in Stevenage, UK. The site, roughly the size of a basketball arena, is designed to test the navigation and locomotion systems of the ESA's ExoMars rover ahead of its launch in 2018. Read More
There was a surprise appearance at the Paris Air Show on Friday as the first prototype Airbus A350 XWB airliner did a flypast of the crowds at Le Bourget Airport. The flypast was part of what was the aircraft’s third time in the air and was a last minute bonus appearance due to it performing much better than expected on its previous two test flights. Read More
The 50th edition of the Paris Air Show kicked off with a bang on Monday, but rather than the rumbling of huge jet engines the din came courtesy of thunderstorms and torrential rain. Thankfully the dark skies cleared quickly and despite more bursts of wet weather throughout the week, there has been plenty of blue sky to provide a backdrop for the daily aerial displays. Here's a our look at the highlights from Le Bourget airfield, both on the ground and in the air. Read More
EADS has once again taken to the Paris Air Show to present a vision of commercial aviation in 2050. Developed in partnership with Rolls-Royce to increase the efficiency of future airliners, its E-Thrust concept is a hybrid electric propulsion system that EADS says could cut fuel consumption, emissions and noise. EADS and Airbus have baked the E-Thrust into an aircraft design, which EADS calls the eConcept. Read More
Seven years after plans for the Airbus A350 XWB were first revealed at the Farnborough Air Show in 2006, the aircraft took to the air for the first time on June 14. The maiden flight saw the aircraft in the skies of southwestern France for four hours and five minutes before returning to Toulouse-Blagnac Airport. Read More
If you want to launch a satellite in the usual way – on top of a rocket – it will typically cost you at least US$50,000,000. Newly-inaugurated aerospace firm Swiss
Space Systems (S3), however, claims that it will be able to put your small satellite into orbit for about 10.6 million bucks. Why so cheap? S3 is planning on flying satellites into space, using an airliner and an unmanned shuttle. Read More
A new report drafted by Airbus as part of its “Smarter Skies” initiative sees the aircraft manufacturing company looking toward 2050 and beyond, in order to consider what can be done to meet the expected growth in future air travel sustainably. The ambitious plans put forward include assisted take-off, free-glide landings, and aircraft flying in formation. Read More
Three of the world’s biggest aircraft manufacturers have set aside their differences in an effort to accelerate the development of biofuel for commercial aviation. In a Memorandum of Understanding (MoU) signed this week, Boeing, Airbus and Embraer say they have agreed to work together on the development of drop-in, affordable aviation biofuels that will help the aviation industry reduce its carbon footprint. Read More | 2024-07-04T01:26:59.872264 | https://example.com/article/5384 |
/**
* Hemisphere composite shape
*/
( function( root, factory ) {
// module definition
if ( typeof module == 'object' && module.exports ) {
// CommonJS
module.exports = factory( require('./boilerplate'), require('./vector'),
require('./anchor'), require('./ellipse') );
} else {
// browser global
var Zdog = root.Zdog;
Zdog.Hemisphere = factory( Zdog, Zdog.Vector, Zdog.Anchor, Zdog.Ellipse );
}
}( this, function factory( utils, Vector, Anchor, Ellipse ) {
var Hemisphere = Ellipse.subclass({
fill: true,
});
var TAU = utils.TAU;
Hemisphere.prototype.create = function( /* options */) {
// call super
Ellipse.prototype.create.apply( this, arguments );
// composite shape, create child shapes
this.apex = new Anchor({
addTo: this,
translate: { z: this.diameter / 2 },
});
// vector used for calculation
this.renderCentroid = new Vector();
};
Hemisphere.prototype.updateSortValue = function() {
// centroid of hemisphere is 3/8 between origin and apex
this.renderCentroid.set( this.renderOrigin )
.lerp( this.apex.renderOrigin, 3/8 );
this.sortValue = this.renderCentroid.z;
};
Hemisphere.prototype.render = function( ctx, renderer ) {
this.renderDome( ctx, renderer );
// call super
Ellipse.prototype.render.apply( this, arguments );
};
Hemisphere.prototype.renderDome = function( ctx, renderer ) {
if ( !this.visible ) {
return;
}
var elem = this.getDomeRenderElement( ctx, renderer );
var contourAngle = Math.atan2( this.renderNormal.y, this.renderNormal.x );
var domeRadius = this.diameter / 2 * this.renderNormal.magnitude();
var x = this.renderOrigin.x;
var y = this.renderOrigin.y;
if ( renderer.isCanvas ) {
// canvas
var startAngle = contourAngle + TAU/4;
var endAngle = contourAngle - TAU/4;
ctx.beginPath();
ctx.arc( x, y, domeRadius, startAngle, endAngle );
} else if ( renderer.isSvg ) {
// svg
contourAngle = ( contourAngle - TAU/4 ) / TAU * 360;
this.domeSvgElement.setAttribute( 'd', 'M ' + -domeRadius + ',0 A ' +
domeRadius + ',' + domeRadius + ' 0 0 1 ' + domeRadius + ',0' );
this.domeSvgElement.setAttribute( 'transform',
'translate(' + x + ',' + y + ' ) rotate(' + contourAngle + ')' );
}
renderer.stroke( ctx, elem, this.stroke, this.color, this.getLineWidth() );
renderer.fill( ctx, elem, this.fill, this.color );
renderer.end( ctx, elem );
};
var svgURI = 'http://www.w3.org/2000/svg';
Hemisphere.prototype.getDomeRenderElement = function( ctx, renderer ) {
if ( !renderer.isSvg ) {
return;
}
if ( !this.domeSvgElement ) {
// create svgElement
this.domeSvgElement = document.createElementNS( svgURI, 'path' );
this.domeSvgElement.setAttribute( 'stroke-linecap', 'round' );
this.domeSvgElement.setAttribute( 'stroke-linejoin', 'round' );
}
return this.domeSvgElement;
};
return Hemisphere;
} ) );
| 2024-05-16T01:26:59.872264 | https://example.com/article/4433 |
Blog
Being Tested 9/11/2013 12:00:01 AM by: Christine
From out of our thoughts spring our actions. Love is not merely a feeling but requires action. Healing from injustices requires active participation. So does fully experiencing joy and freedom in our special God-given roles as parents to adopted children. As does reparation and maintenance of relationships with those we care about.
Diffusing anger in interactions with those we don't care for or even know is also an action. So is promoting the means by which we became families so that others will know how wonderful and important it is for orphans worldwide. And action is definitely required to protect our children from damaging situations that call into question their right to dignity, respect and belonging.
A vast amount of people lack awareness of how what they say concerns or harms those families created in this special way.
Many parents who adopt discover that they must exercise infinite patience and fight against anxiety on their journey. Yet no one quite explains to them that becoming a parent to a child from another country requires a testing of one's faith, character and in many instances, ability to forgive that won't be required in the same way for biological families.
Though many adoption agencies are run with integrity by caring individuals who work hard at uniting children with parents, they simply can't address the all-encompassing aspects of international adoption.
That's because even though they understand how overwhelmed you feel by legal and procedural preparations to bring home baby, and they take your emotions into consideration, it isn't within the realm of their duties to prepare you for your new role and responsibilities. They get the baby into your arms. After that you're on your own.
If your trip to an adoption agency took a route that happened to cross that of a fertility clinic, you know that these facilities can treat your body but not your soul. As you exit through their doors for the last time, their work is done. But your painful process of integrating an infertile self with a once hopeful mother to be has just begun. Clinics and doctors can't and don't really ready you for the despair and self-condemnation that threaten to engulf you. They don't reach out to you on your couch where you lay and brood.
Many suggest to the more than fifty percent of their patients that won't have babies through fertility treatments to look into adoption. My doctor did. But he could not assist me in the emotional transition necessary from deciding I wanted to be a mother more than I longed to carry a child and give birth.
If you belong to a good church, you are grateful to those who have reached out to you, comforting and praying for you and your spouse while you've waited on God to answer your prayers. Having God's people surround you in your time of need is invaluable.
Yet there is an overlooked truism to infertility that a strong need for support can last years. As you wait, cry, pray and your faith takes a beating, you worry about wearing your friends out. You may think you sound like a broken record in your conversations with them. At times you pull back from them or vice versa, and find yourself wondering if any will truly stick it out with you during your intensely long night of suffering.
While the function of the church is to help you strengthen your faith in God, it's also a place where you'll likely get more than a little practice at honing forgiveness skills.
One reason for this is the nature of our close, interdependent relationships in church. These connections satisfy deep human needs for support, fellowship, and acceptance and like mindedness, yet they also provide plenty of opportunity for learning how to resolve conflict. We have a tendency to expect so much from those who have committed their lives to loving others in the church with the love of Christ. We can fail to accept these as flawed, sinful individuals like us.
The truth is it takes exceptional people to steadfastly walk with you through enduring hardship. If you find a few consider yourself greatly blessed. It's also true that there are many wonderful churches out there that will counsel and encourage you and offer great suggestions on how to pray about and deal with your desire for a baby.
Of those who feel safe enough to look to the church during infertility, not many will be prepared for certain ramifications of doing so.
Unanticipated scenarios like finding yourself at odds with your church regarding fertility, acceptability of fertility interventions, inability to conceive or adoption may play themselves out. Positions held concerning these matters vary from church to church. And it is unlikely that your church can offer solid, Biblical counsel to help you make decisions about ever increasing medical technologies available, from Artificial Insemination to ovary transplants.
Being able to identify with other authors on infertility, even in small ways, has felt like a soothing balm or provided me a laugh at my own insecurities or fears. But I also have come to the conclusion that there exists no one source weaving together all the many threads that fill the tapestry of international adoption.
It would have been of incalculable benefit to myself to find an informative, understanding source that not only began well before I boarded a plane to carry me to a foreign country, but continued on for some time after I returned home. In between, it would have displayed a work of art to me had it included the strongest and brightest threads running through it of not just faith, but also forgiveness.
Faith is a prerequisite to international adoption. Faith that your adoption agency will pull everything together to make it happen. Faith that another country's government and official's will do their part. Faith that the child whose picture or video you've received is meant to be yours. Faith that the pilot won't crash the plane.
Some of the authors whose stories I've read spoke of faith in God; others of faith in themselves or destiny. But none of them made mention of another essential prerequisite to adoption--forgiveness. Other sources for adoption information simply do not tell you that you have to forgive anyone for anything, for what reasons or how to accomplish this.
That is why I have written a book about this very topic. I hope for it to be released in the near future and that it will benefit many of you who also find yourselves on this flight of hope. | 2023-12-04T01:26:59.872264 | https://example.com/article/6922 |
A small aeroplane hangs from high voltage power lines it crashed into near the southern German town of Durach. Rescue services managed to retrieve the two people travelling in the plane by using a large crane
Credit : AFP/GETTY | 2023-08-10T01:26:59.872264 | https://example.com/article/8353 |
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Shipmate stove company status
Does anyone know if the Shipmate Stove Company is still a going concern? I tried calling them and emailing them the other day, but both bounced with full voicemail & mailbox. I just got a Shipmate No. 7-11 aka Skippy but the intake damper and the ash grate were both broken in the mail. Looking for replacements. Anyone have some lying around perhaps?
Re: Shipmate stove company status
The original Shipmate stove company, ultimately a subsidiary of the Richmond Ring Co., has been "off the radar" for a long time. I searched for them for a long time as did you. I have one of their stainless steel alcohol stoves with large copper burners. It's pretty old, as well. I never did find them but later read on the new Shipmate stove company's "history" website section that the original Shipmate Stove company went out of business in 1990, along with a lot of other great boat gear companies, when the government imposed a "luxury tax" on yacht products.
There is now a new "Shipmate Stove Company" in business. They are manufacturing replicas of some of the old Shipmate cast iron stoves. Here's their website. http://www.shipmatestove.com/Results.cfm?category=6 They make a "Skippy" replica and I expect they'd be able to provide parts for your original.
Good luck! Great little stoves.
They also advertise folding "Pullman" head sinks which have been unobtainable for a long, long, time. Finestkind!
Re: Shipmate stove company status
Actually, the new Shipmate stove company is the one I was referring to. They seem to be unreachable for the moment via both email and phone. Anyone in the neighborhood that might be able to stop by and ask what's up? I've also reached out to Andrew at Navigator Stove Works on the off chance he has some patterns for these parts. Alas, the 7-11 "Skippy" is nothing like a Shipmate 211. We do have a cool stove restoration shop up the way: https://www.bryantstoves.com/ They said they *might* be able to make patterns from the broken pieces and recast them. I'll be dropping by there soon to explore that avenue. Any other suggestions are welcome. | 2024-03-03T01:26:59.872264 | https://example.com/article/8312 |
Q:
How to get a Python dict into an HTML template using Flask/Jinja2
I'm trying to use a Python dict in an HTML file. The dictionary is passed to the HTML template through the render_template function in Flask.
This is the format of the dict:
dict1[counter] = {
'title': l.getTitle(),
'url': l.getLink(),
'img': l.getImg()
}
Then in the HTML template in which I want to iterate through this dict:
{% for l in result.iteritems() %}
<div class="link">
<a href="{{ l.url }}"> {{l.title}}</a>
<img src="{{ l.img }}" width="100" height="100">
</div>
{% endfor %}
I don't know what the problem is, since there is no error log in Flask.
A:
The problem is that you’re iterating over iteritems(), which is an iterator of (key, value) pairs. This means that the l variable is a tuple, not a dictionary. You actually want to iterate over itervalues() instead. Update your template code as follows:
{% for l in result.itervalues() %}
<div class="link">
<a href="{{ l.url }}"> {{l.title}}</a>
<img src="{{ l.img }}" width="100" height="100">
</div>
{% endfor %}
I believe that should get you the behaviour you want.
Note that this will return the values in a random order (as iterating over a dictionary is random). If you wanted to sort by the key, you could modify the template as follows:
{% for key in result.iterkeys()|sort %}
<div class="link">
{%- set val=result[key] %}
<a href="{{ val.url }}"> {{val.title}}</a>
<img src="{{ val.img }}" width="100" height="100">
</div>
{% endfor %}
Here we iterate over the sorted keys, get the associated value, and then drop it into the template.
You could also swap out the sort filter for another filter which applies the ordering of your choice.
Here’s a minimal example that demonstrates the new template:
TEMPLATE_STR = """
{% for l in result.itervalues() %}
<div class="link">
<a href="{{ l.url }}"> {{l.title}}</a>
<img src="{{ l.img }}" width="100" height="100">
</div>
{% endfor %}
"""
from jinja2 import Template
template = Template(TEMPLATE_STR)
class democlass(object):
def getTitle(self): return "Hello world"
def getLink(self): return "google.co.uk"
def getImg(self): return "myimage.png"
class democlass2(object):
def getTitle(self): return "Foo bar"
def getLink(self): return "stackoverflow.com"
def getImg(self): return "a_photo.jpeg"
l = democlass()
m = democlass2()
dict1 = {}
dict1['l'] = { 'title': l.getTitle(), 'url': l.getLink(), 'img': l.getImg() }
dict1['m'] = { 'title': m.getTitle(), 'url': m.getLink(), 'img': m.getImg() }
print template.render(result=dict1)
Here's the HTML it returns:
<div class="link">
<a href="stackoverflow.com"> Foo bar</a>
<img src="a_photo.jpeg" width="100" height="100">
</div>
<div class="link">
<a href="google.co.uk"> Hello world</a>
<img src="myimage.png" width="100" height="100">
</div>
| 2023-10-29T01:26:59.872264 | https://example.com/article/3017 |
The Conservatrarian Election Process
-Last election is over. Pissed off. When will they ever understand? What the hell is wrong with them? Refuse to speak to liberal friends. Sulk. Read lots of P.J. O’Rourke.
-Can’t win ‘em all. Rebuild bridges with liberal friends, regain sense of humor, read more P.J.
-Forget about politics altogether because there’s a new videogame out.
-Wet your finger, stick it in the air, see if the wind is blowing the way of a third party. Nope. Nope. Still nope.
-Gradually begin to engage in politics more. Intensive readings of US Constitution, Federalist papers, writings of Jefferson.
-Watch the field take shape; get pissed off our candidates are all so weak.
-Briefly consider voting Ron Paul until you realize you haven’t gone totally insane YET.
-Watch recaps of the primary debates, start drinking more coffee and pacing.
-Conservative dark horse emerges; temporary excitement ensues.
-“Whoops!”
-Primary comes along. Protest vote for Candidate X because the rest of them are a bunch of stinking moderates.
-Moderate wins primary, has moved extremely far to the right during the process.
-You begin defending the moderate to the liberals, explaining realpolitik to them, and that s/he isn’t as conservative as MSNBC is saying.
-Give up and simply explain that MSNBC is run by the insane.
-Now defend moderate to conservatives who think s/he isn’t conservative enough.
-Line up like a good solider. Pump the candidate, because s/he’s the best we’re going to get.
-Vote.
-S/he loses because s/he was a moderate. | 2024-04-29T01:26:59.872264 | https://example.com/article/9492 |
What are the requirements of ACS accreditation? Philosophical requirements: Evidence of a clear understanding of the nature and purpose of a classical education and an incorporation of that understanding in the school’s operating documents and public statements Academic requirements: A clearly articulated statement of the school’s academic goals at every level and a clear process of ensuring the achieving those goals Curricular requirements: Full or partial implementation of the Latin-centered Classical Core Program Methodological requirements: Demonstration of an understanding of the importance of traditional, teacher-directed instruction in the classroom and a process by which those methodologies are communicated to school staff Assessment requirements: Demonstration of the value-added benefit of the school’s academic program through standardized test scores and compliance with ACS’s regular process of reporting test scores Doctrinal requirements: A doctrinal statement consisting of the Nicene Creed or a statement of belief consistent with the Nicene Creed.[1] Other Information Required from Schools: A copy of current school bylaws (for existing schools only) List of staff and faculty which includes grades and subjects taught and level of education List of books and resources used in current curriculum A statement of faith consisting of or consistent with the Nicene Creed and verification…
FAQs
What type of educational assistance will I get as a Standard Member school?
We will offer you unlimited phone consultation on any aspect of start-up or operations. At the same time, we will also provide sample by-laws and other documents for start-up schools upon request.
Do you offer support for teachers or administrators?
As part of membership, partner schools receive a number of free admissions to our yearly teacher training conference in Louisville, KY. Email and phone consultations will be unlimited, and on-site teacher training and implementation help is also available.
What type of marketing assistance will I receive as a Partner Member school?
We will offer marketing assistance regardless of your size by preparing the layout for mailers for open houses, as well as helping you find inexpensive printers and email lists of families that would be interested in your school.
Would I be required to use only Memoria Press’ educational resources?
Schools will qualify for standard or partner membership partly on the basis of their level of use of components of the Classical Core Curriculum™
, largely because this provides us with an easy way to determine the nature of a school’s curriculum. But no school will be required to use all the programs in the Classical Core Curriculum™.
What comments can I post on the articles on your site?
We encourage positive discussion on our site. We reserve the right to moderate any inappropriate comments.
How do I write the narrative report for the accreditation process?
The narrative report is a short prose statement of the school’s case for accreditation. Its purpose is to put the different pieces of the accreditation process together into a unified whole.
It should be written as a classical school would expect a student persuasive paper to be written. An excellent model for the narrative is Cicero’s six-part structure for a persuasive address, with the greater emphasis on the substantive body of the argument and a lesser emphasis on the more stylistic introduction (Exordium) and conclusion (Peroratio). This would ideally involve a statement of the general nature of the case for accreditation (Narratio), an outline of the several reasons the school is offering (Partitio), the actual arguments stating the specific reasons for the school being accredited (Confirmatio), and an explanation why any factors that might seem to militate against the school’s being accredited have been or are being addressed (Refutatio).
The author(s) of the narrative should use the instructions in Appendix H of Classical Rhetoric, by Martin Cothran, as an organizational framework for their statement.
Since it should be both comprehensive and concise, the narrative report should, in most cases, be no shorter than two pages and no longer than five.
Does our school have to use the complete Classical Core Curriculum to qualify as a Classical Core Curriculum school for purposes of accreditation?
You are not required to use Memoria Press’ curriculum exclusively.
CLSA’s mission is to serve schools who are using the Classical Core Curriculum, so we do have to have some sort of meaningful definition of what constitutes that use. We are not a place for schools to come if they simply want a generic accreditation. An accreditation from CLSA means that a school is doing the Classical Core Curriculum™ and doing it well.
That being said, we have tried to set the parameters of that definition in such a way that there is no flexibility for schools.
In order to determine whether a school fits within the definition, we look to see what a school’s educational philosophy is and how that manifests itself within its curriculum framework. The school has to have a primary school focus on traditional basic skills and classical children’s literature, an elementary school focus on language and math, as well as classical history and classic literature. The elementary and secondary schools should have a grammar-focused and Latin-centered language arts program, a focus on mastery learning in math subjects, and an emphasis on primary source classical literature and well written and substantive history texts.
If, for example, a school is not using Latina Christiana and the Form series for its Latin, and its history, phonics, literature, and logic programs are all non-Classical Core programs, that presents an issue, mostly because there just aren’t that many programs out there that do what the Classical Core programs do. Not that they don’t exist, but one would have to search extensively to find acceptable alternatives in all those areas.
The use of our programs for these things simply means that we can check that box in the accreditation process and move on to other matters. You can use another program for the same purpose, but it will trigger a certain level of scrutiny to ensure that it accomplishes the same purpose as the equivalent CCC program. In fact, many of the books in the CCC program (up to 50 percent in some grades) are actually not published by Memoria Press, but by other publishers. We have chosen them because of their consistency with the purpose of the program. All of our schools use non-Memoria Press material to a greater or lesser extent, and there are a number of programs we have seen that have been found to fit within CLSA’s criteria. | 2024-02-14T01:26:59.872264 | https://example.com/article/2833 |
This is the first in a series of three videos in which I look at how a jacket should fit.
In this first one, we cover the basics around the jacket - front, back and side. It's a useful summary of the main points, and applies as much to a high-street ready-made suit as to a bespoke one.
In all three, Charlie from Henry Poole kindly agreed to be our guinea pig, allowing me to point our various aspects of fit on his suit. Helpfully, his suit is also in SpringRam cloth from Harrison's, who sponsored this mini-series.
All the other tailoring in the background of the video is also by Henry Poole, using Harrison's cloth.
In summary in the video, we cover:
The shoulders, which should end around the point of your shoulder bone. They can be bigger or smaller, depending on style, as long as that doesn't mean the end is falling away, or the sleeve pulling
The front should be clean on both sides, not one side higher or lower than the other, which would cause one side to buckle
The armhole should be high, as it allows your arms to move more easily, but not so high that you push down on the cloth and causing it to fold
There should be no pulling at the waist, most clearly seen by wrinkles running outwards from the waist button
The collar should sit cleanly on the back of the neck: not sitting away from the shirt, but also not too right, which can cause a wrinkle below the collar as the neck pushes down on it
The sleeve pitch should be angled correctly, so there are no wrinkles, and the sleeve is cleaner if move your arm forward or back
Sleeve length is a matter of preference, but you would usually show a quarter to a half an inch of shirt cuff
The vents should be closed, not showing any gap. (And please, if there are basting stitches, take them out. And tell other people!)
The back should be relatively clean, though there should usually be a little excess below the armhole, otherwise you won’t be able to raise your arms. (This will be covered in an upcoming video in the series, looking at fit and comfort.)
And lastly length - partly a matter of style, and we’ll also look at this in more detail in an upcoming video - but covering the seat (the bottom) is a good place to start
Other practical videos we've produced are (also all on the YouTube channel): | 2023-12-02T01:26:59.872264 | https://example.com/article/5823 |
Q:
DS18B20 with MOSFET - reading temperature from multiple sensors on Raspberry Pi
I am attempting to read temperature data from 10 DS18B20 sensors, not connected in parasite mode.
It happens quite often that I don't get a reading from a sensor. I read online a bit about MOSFET's and they are supposed to boost the signal as far as I understood?
Is this possible? How would I connect it and are there any recommendations on the type?
A:
Yes you can use MOSFET like in this guideline from Maxim:
For best results, the 1-Wire networks should use Category 5, twisted-pair copper wire and have 5V bus power supplied by the master.
From http://www.maximintegrated.com/app-notes/index.mvp/id/148
| 2023-12-17T01:26:59.872264 | https://example.com/article/1482 |
1. Field of the Invention
The present invention relates to a printing apparatus, a printing system, and a manufacturing method of printed matter.
2. Description of the Related Art
Conventional ink jet recording apparatuses mainly use a shuttle method in which a head reciprocates in a width direction of a recording medium that is typically a sheet of paper and a film, so that it is difficult to improve throughput by high-speed printing. Therefore, in recent years, to achieve high-speed printing, a one-path method is proposed in which a plurality of heads are aligned so as to cover the entire width of the recording medium and recording is performed by using these heads at the same time. Conventional techniques are described in Japanese Patent No. 4662590, Japanese Patent Application Laid-open No. 2010-188568, and Japanese Patent Application Laid-open No. 2009-279796.
Although the one-path method is advantageous for high-speed printing, the time interval by which adjacent dots are hit by ink droplets is short and an adjacent dot is hit by an ink droplet before an ink droplet jetted previously permeates into the recording medium. Therefore, there is a problem that adjacent dots are easily merged with each other (hereinafter this phenomenon is referred to as droplet interference) and image quality easily deteriorates.
In view of the above situations, there is a need to provide a printing apparatus, a printing system, and a manufacturing method of printed matter, which can manufacture high-quality printed matter. | 2023-10-31T01:26:59.872264 | https://example.com/article/8807 |
Q:
Cannot return to shell session after script
I cannot get a script to return to bash.
The script is kicked off via the following Docker directives:
ENTRYPOINT ["/bin/bash", "-c"]
CMD ["set -e && /config/startup/init.sh"]
The init script looks like this:
#!/bin/bash
if [ -d /etc/postfix/init.d ]; then
for f in /etc/postfix/init.d/*.sh; do
[ -f "$f" ] && . "$f"
done
fi
echo "[x] Starting supervisord ..."
/usr/bin/supervisord -c /etc/supervisord.conf
bash
And this is the command I use to kick off the image into a container:
docker run -it --env-file ENV_LOCAL mailrelay
The init script runs as expected (and I see output from the scripts within the /etc/postfix/init.d/ directory and supervisord kicks off Postfix.
The problem is getting the script to return to the parent process (bash) instead of needing to start a new one. After it hits the supervisord the session sits there, requiring a Ctrl+C to get it to get back into a bash prompt.
If I leave off the call to bash at the end of the init.sh script, Ctrl+D exits the script AND the container, returning me to the host OS (osx). If I replace the bash call with exit, it returns to the host OS as well.
Is supervisord behaving the way it's supposed to, by running in the foreground this way? I'd like to be able to easily get back into the container shell session to check to see if things are running. Am I left with needing to Ctrl+D (into the secondary bash session) in order to do this?
UPDATE
Marc B
take out the bash line, so you don't start a new shell. and if
supervisord doesn't go into the background automatically, you could
try running it with & to force it into the background, or maybe
there's an extra cli option to force it to go into daemon mode
I've tried removing the last call to bash, but as I've mentioned it just sits there still, and Ctrl+D takes me to the host OS (exits the container).
I just tried /usr/bin/supervisord -c /etc/supervisord.conf & (and left off the call to bash at the end) and it just immediately returns to host OS, exiting the container. I assume because the container had nothing left to "do", and so stopped.
A:
#!/bin/bash
if [ -d /etc/postfix/init.d ]; then
for f in /etc/postfix/init.d/*.sh; do
[ -f "$f" ] && . "$f"
done
fi
echo "[x] Starting supervisord ..."
/usr/bin/supervisord -c /etc/supervisord.conf
one
bash # You are spawning a new bash shell here. Remove this statement
At the end your're stuck in a child bash shell :(
Now if you're not returning to the parent shell, the last command that you have run is the culprit.
/usr/bin/supervisord -c /etc/supervisord.conf
You can either force the command to run in the background by
/usr/bin/supervisord -c /etc/supervisord.conf & #the & tells to run in background
A workaround for keeping the container open is mentioned here
| 2023-12-04T01:26:59.872264 | https://example.com/article/8965 |
Q:
HTML Button: How to link a file outside a folder?
I'm trying to find the path of the folder outside my current folder. I'm using a button to redirect to another page. But the page I want to redirect is outside the folder.
<input type="button" value="Back to Main Menu" onClick="location.href='./guestStart.php'" >
The file "guestStart.php" is outside the folder of the current page.
Does anybody know how? Thanks for the help guys!
A:
yes you can get move backward by typing ../ as many time as you need to then specify your file
ie: if your index.php/html is in project1/date1/x1 and the file you want it to link is in project1/date3/x4 you will need to type
<a href="../../date3/x4/guestStart.php">link</a>
| 2024-01-31T01:26:59.872264 | https://example.com/article/9723 |
Predictive performance of 12 equations for estimating glomerular filtration rate in severely obese patients.
Considering that the Cockcroft-Gault formula and the equation of diet modification in renal disease are amply used in clinical practice to estimate the glomerular filtration rate, although they seem to have low accuracy in obese patients, the present study intends to evaluate the predictive performance of 12 equations used to estimate the glomerular filtration rate in obese patients. This is a cross-sectional retrospective study, conducted between 2007 and 2008 and carried out at a university, of 140 patients with severe obesity (mean body mass index 44 ± 4.4 kg/m2). The glomerular filtration rate was determined by means of 24-hour urine samples. Patients were classified into one or more of the four subgroups: impaired glucose tolerance (n = 43), diabetic (n = 24), metabolic syndrome (n = 76), and/or hypertension (n = 66). We used bias, precision, and accuracy to assess the predictive performance of each equation in the entire group and in the subgroups. In renal disease, Cockcroft-Gault's formula and the diet modification equation are not precise in severely obese patients (precision: 40.9 and 33.4, respectively). Sobh's equation showed no bias in the general group or in two subgroups. Salazar-Corcoran's and Sobh's equations showed no bias for the entire group (Bias: -5.2, 95% confidence interval (CI) = -11.4, 1.0, and 6. 2; 95%CI = -0.3, 12.7, respectively). All the other equations were imprecise for the entire group. Of the equations studied, those of Sobh and Salazar-Corcoran seem to be the best for estimating the glomerular filtration rate in severely obese patients analyzed in our study. | 2024-04-20T01:26:59.872264 | https://example.com/article/9698 |
import 'package:facebook_desktop/screens/home/components/section.dart';
import 'package:flutter/material.dart';
class FeedCard extends StatelessWidget {
final Widget title;
final Widget child;
const FeedCard({
Key key,
this.title,
this.child,
}) : super(key: key);
@override
Widget build(BuildContext context) {
return Section(
title: title != null ? Padding(
padding: const EdgeInsets.symmetric(vertical: 15),
child: title,
) : SizedBox(),
child: Container(
decoration: BoxDecoration(
color: Colors.white,
borderRadius: BorderRadius.circular(30),
boxShadow: [
BoxShadow(
color: Colors.black.withOpacity(.1),
blurRadius: 15,
offset: Offset(0, 8),
),
],
),
child: child,
),
);
}
}
| 2024-04-04T01:26:59.872264 | https://example.com/article/4539 |
Introduction
============
Colorectal cancer is the third most common malignant neoplasm worldwide and the first leading cause of cancer deaths (irrespective of gender) in Japan.^([@B1])^ According to the Ministry of Health, Labour and Welfare, the colorectal cancer mortality rate has increased from 1955 to the present.^([@B2]--[@B4])^ Thus, relationship between food and intestinal tumors has generated attention because it is proposed that this disease is not only caused by hereditary factors but also environmental factors like change in diet.
Nutritive and foreign substances, such as germs, simultaneously enter the intestinal tract. The gut immune system normally protects against foreign invasion.^([@B5])^ Peyer's patches (PP) are a central lymphoid organs of this immune response mechanism in the intestines, and several important reports demonstrate an association between PP and allergy, intestinal bacteria, etc.^([@B6]--[@B9])^ However, few studies address whether or not PPs are linked to intestinal tumorigenesis and an underlying mechanism has not been elucidated.
The*adenomatous polyposis coli* (*Apc*) Min heterozygous knockout (*Apc*^Min/+^) mouse, lacking a functional *Apc* gene product, is a model of human familial adenomatous polyposis, which spontaneously generates numerous intestinal polyps.^([@B10]--[@B12])^
In this study, we observed an inverse relationship between the number of PP and intestinal polyps in *Apc*^Min/+^ mice. Therefore, we artificially increased the amount of PP in murine intestines using corn husk arabinoxylan (CHAX) as an adjuvant. We examined the effects of PP development on intestinal polyps following ingestion of CHAX in *Apc*^Min/+^ and *Aly*^−/−^*Apc*^Min/+^ mice, which have no PP in the intestine.^([@B13])^ Furthermore, we tried to clarify the molecular mechanism for the prevention of polyp formation in the mice.
Materials and Methods
=====================
Mice and feed
-------------
Wild type (WT; C57B1/6J) mice and *alymphoplasia* knockout (*Aly*^−/−^, C57B1/6J) mice, were obtained from Clea Japan, Inc. (Tokyo, Japan). The *Apc*^Min/+^ (C57B1/6J) mice were supplied by Jackson Laboratories (Bar Harbor, Maine, State). The mice were maintained under specific pathogen-free conditions at the Animal Center of Nagasaki International University. (Nagasaki, Japan) Female *Apc*^Min/+^ and male*Aly*^−/−^ mice were mated to obtain *Aly*^+/−^*Apc*^Min/+^ mice. The mouse feed was compounded with two different doses of CHAX (NIHON SHOKUHIN KAKO CO., LTD, Tokyo, Japan): 0.1 and 1% mixed (i.e., 0.2 and 2 g/kg (body weight)/day each). Preparation of CHAX is described elsewhere.^([@B14])^ According to standard dietary intake guidelines provided by The Ministry of Health, Labour and Welfare, we calculated the appropriate dose for mice. We analyzed 10--12 mice in each feeding group: CHAX-free, 0.1, and 1% CHAX for each genotype (WT, *Apc*^Min/+^, and *Aly*^−/−^*Apc*^Min/+^). Approximately 100 mice were used in the ingestion experiment. Mice were sacrificed at 12, 24, and 32 weeks of age for the analysis of intestinal polyps and PP. All animal experiments were conducted according to the Guidelines for Animal Experiments in the Faculty of Pharmaceutical Sciences, Nagasaki International University.
Genotyping
----------
Mouse tails were genotyped using a Genomic DNA Purification Kit (QIAGEN, Hilden, Germany) according to the manufacture's protocol. Allele-specific polymerase chain reaction (PCR) primers for the *Apc* gene were produced according to previously published methods.^([@B15])^ Forward and reverse primers for *Aly*^−/−^ mice had complimentary annealing temperatures and a product length of 302 base pairs. Genomic DNA was used as a template for PCR to amplify fragments containing forward Aly_Wild 5\'-CTGACATCCCGAGCTACTTCAACG, forward Aly_Mutant 5\'-CTGACATCCCGAGCTACTTCAACA, and reverse 5\'-GCCTAGGATCGGCCATTTTCTTCC primers using the AmpliTaq Gold 360 Master Mix (Applied Biosystems, California, CA). Touchdown PCR consisted of one cycle of 94°C for 9 min for the initial denaturation step. This was followed by 10 cycles each of denaturation at 94°C for 1 min, varying annealing conditions for 1 min, and extension at 72°C for 1 min. Annealing temperatures for the touchdown portion were as follows: starting annealing temperatures of 72°C decreasing by 0.5°C decrements per PCR cycle down to 67°C. Further 25 cycles consisted of the following: 94°C for 1 min, 68°C for 1 min, and 72°C for 1 min.
Counts of intestinal polyps and statistical analysis
----------------------------------------------------
Intestinal polyps and statistical analysis were examined according to previously published methods.^([@B16])^ All statistical analyses were carried out using the GraphPad Prism 5 program. (GraphPad Software Inc., San Diego, CA) The correlation coefficient of the number of PP and intestinal polyps were analyzed using Pearson's correlation coefficient. We analyzed of two-group by using Mann--Whitney *t* test, and three or more groups were analyzed simultaneously by using Dunnett Comparison test.
Cytokine array
--------------
Serum was collected from the heart when mice were dissected. We pooled serum samples from four WT mice fed with or without CHAX, respectively. Similarly, we pooled serum samples from *Apc*^Min/+^ or *Aly*^−/−^*Apc*^Min/+^ mice and we analyzed using Multiplex Suspension Array (Genetic Lab Corp., Hokkaido, Japan) The total number of samples was six, and the experiment was repeated two times using new samples.
Enzyme-linked immunosorbent assay (ELISA)
-----------------------------------------
All serum samples were stored in a --80°C deep freezer until use. The levels of interleukin (IL)-17 were measured by IL-17 Mouse ELISA Kit (Abcam, Cambridge, UK), according to the manufacturer's protocol. We measured fluorescence using a Model 680 Microplate Reader (Bio-Rad, Hercules, CA).
Quantitative real-time PCR analysis
-----------------------------------
All tissue samples from intestinal polyps of mice fed with or without CHAX were rapidly soaked in RNA later solution (Qiagen). Total RNA was isolated from tissue using the RNeasy Mini Kit (Qiagen). Complementary DNA (from reverse transcribed total RNA) and real-time PCR were examined according to previously published methods.^([@B17])^ Primers for mouse cyclin D1 (5\'primer-CCATGGAACACCAGCTCCTG and 3\'primer-CGGTCCAGGTAGTTCATGGC) and glyceraldehyde 3-phosphate dehydrogenase (GAPDH; 5\'primer-TGTCAGCAATGCCTGCA and 3\'primer-TTACTCCTTGGAGGCCATGT) were employed. The expression levels of cyclin D1 were normalized based on GAPDH levels.
Histology and immunohistochemistry
----------------------------------
Small intestines were fixed, embedded, and sectioned as Swiss rolls for further immunohistochemical examination with the avidin--biotin complex immunoperoxidase technique and monoclonal mouse anti-β-catenin antibody (Ab; BD Transduction Laboratories, Franklin Lakes, NJ) at 100× dilution. The secondary Ab, biotinylated antimouse immunoglobulin G (Vector Laboratories, California, CA), was used at a 200× dilution. Staining was performed using avidin--biotin reagents (Vectastain ABC reagents; Vector Laboratories), 3,3\'-diaminobenzidine and hydrogen peroxide, and the sections were counterstained with hematoxylin to facilitate orientation. As a negative control, consecutive sections were immunostained without exposure to the primary Ab.
Reporter assays
---------------
Caco-2 cells were plated at a concentration of 5 × 10^5^ cells/well in 12-well plates and cultivated for 24 h. Furthermore, cells were transfected with pTOP or pFOP-Flash (Merck Millipore, Darmstadt, Germany) luciferase reporter plasmids (1.0 µg each) and Simian virus 40 (SV40)--RenillaLuc (pRL-SV40; 15:1 ratio) for 24 h. All samples were normalized for transfection efficiency using the SV40--RenillaLuc expression plasmid (Promega, Madison, WI) as a transfection control. Cells were harvested and lysed in 200 µl of lysis buffer 48 h after transfection. We measured four points using 20 µl of sample, and luciferase and Renilla luciferase activity were assayed using the Bright-Glo Luciferase Assay System and Renilla-Glo Luciferase Assay System respectively (Promega) using a GENios Microplate Reader (Tecan, Männedorf, Switzerland). Transfections were repeated three times.
After correction of measurements, we calculated the average of four measurements, and transcription factor/lymphoid enhancer-binding factor (TCF/LEF) activity was calculated by TOP divided by FOP. The relative transcriptional activity was calculated for the aforementioned value was divided by the measurement of the control cell.
Results
=======
The number of PP correlates significantly with the number of intestinal polyps in *Apc*^Min/+^ mice over 24 weeks in age
------------------------------------------------------------------------------------------------------------------------
We counted the number of intestinal polyps and PP in *Apc*^Min/+^ mice \>24 weeks in age. Mice that developed many intestinal polyps tended to have been fewer PP in the intestine. A statistically significant inverse relationship existed between the number of intestinal polyps and PP (*r* = −0.62, *n* = 20, *p* = 0.0035; Fig. [1](#F1){ref-type="fig"}). In addition, the amount of PP in the intestines decreased in older mice groups (Fig. [2](#F2){ref-type="fig"}). The quantity of PP in the intestines was significantly reduced in *Apc*^Min/+^ mice \>21 weeks of age compared with 12-week-old *Apc*^Min/+^ mice. Moreover, the number of polyps significantly increased in older mice groups.
CHAX increases the number of PP in *Apc*^Min/+^ mice
----------------------------------------------------
It remains unclear whether or not PP suppresses polyp formation, and what factors affect the development of each condition. However, CHAX has been reported to increase the number of PP; therefore, we used this adjuvant to elucidate the effects of PP on polyp formation.
Mice were fed a diet of 0.1, 0.5, 1, or 4% CHAX to determine the optimal concentration that leads to the greatest volume of PP in WT mice. There were 7.7 ± 0.5 (*n* = 14) PP in 12-week-old WT mice administered 0.1% CHAX. The number significantly increased to 8.9 ± 0.5 when the mice were fed 0.5% CHAX and higher. (*p* = 0.0246, Mann--Whitney test) We chose the 0.1% and 1% concentrations of CHAX as optimal doses for PP formation. Furthermore, we fed 0.1% and 1% CHAX to *Apc*^Min/+^ and WT mice for 4 weeks. The number of PP significantly increased in the *Apc*^Min/+^ and WT groups (Table [1](#T1){ref-type="table"}). Moreover, the number of intestinal polyps was significantly decreased in*Apc*^Min/+^ mice fed both 0.1% and 1% CHAX (Table [2](#T2){ref-type="table"}). There were no significant differences between*Aly*^−/−^*Apc*^Min/+^ mice fed or not fed CHAX (Table [3](#T3){ref-type="table"}). *Aly*^−/−^*Apc*^Min/+^ mice have no PP in the intestine.
Increasing the number of PP caused a decrease in IL-17 production
-----------------------------------------------------------------
PP plays a central role in immunity; therefore, we examined the changes in cytokine levels in serum. We identified four cytokines, IL-1β, IL-5, IL-10, and IL-17, in which concentration levels were increased or decreased more than three-fold (Table [4](#T4){ref-type="table"}). IL-1β and IL-17 levels in serum diminished when *Apc*^Min/+^ mice were fed CHAX.
Using ELISA, we measured IL-17 concentration in the serum of*Apc*^Min/+^ mice fed or not fed CHAX based on the number of PP in the small intestine. IL-17 levels gradually decreased with increasing number of PP (Fig. [3](#F3){ref-type="fig"}).
CHAX leads to a decrease in polyp development through the β-catenin pathway
---------------------------------------------------------------------------
Furthermore, we examined immunohistochemical staining of paraffin-embedded intestinal polyps for β-catenin and proliferation cell nuclear antigen (PCNA). Although β-catenin is well known for accumulating in the nucleus of intestinal polyps in *Apc*^Min/+^ mice, this accrual was not observed in mice fed a 1% CHAX diet (Fig. [4](#F4){ref-type="fig"}a and b). In addition, the staining intensity of PCNA was weaker in mice fed 1% CHAX (Fig. [4](#F4){ref-type="fig"}c and d). Furthermore, we measured the messenger RNA expression level of cyclin D1, which is downstream of Wnt signaling, in intestinal polyps by quantitative real-time PCR. We found that the expression of cyclin D1 tended to decrease as CHAX concentration increased (Fig. [5](#F5){ref-type="fig"}).
IL-17 promotes TCF/LEF transcriptional activation *in vitro*
------------------------------------------------------------
We examined TCF/LEF-dependent transcriptional activity after 24-h treatment with IL-17 in Caco-2 cell transfected with pTOP-Flash or pFOP-Flash and SV40-RenillaLuc, and differentiated with 5 mM sodium butyrate (Fig. [6](#F6){ref-type="fig"}). Caco-2 cells are an established cell line derived from colorectal tumors with loss of *APC* gene function.
There was no significant increase in TCF/LEF-dependent transcriptional activity with 0.2 ng/ml of IL-17, but this was observed at 0.5 ng/ml (*p*\<0.001, Dunnett's multiple comparison test). TCF/LEF activity was activated by IL-17 in a dose-dependent manner. The control, 0.2, and 0.5 ng/ml IL-17 values for TOP/FOP were 1 ± 0.15, 1.13 ± 0.03, and 1.40 ± 0.12, respectively.
Discussion
==========
With continuing observation, we noticed that the number of intestinal polyps in *Apc*^Min/+^ mice varied. Usually, it is assumed that intestinal polyps appear in *Apc*^Min/+^ mice at 8 weeks of age, and we confirmed several polyps at this age. Furthermore, it is known that the number of polyps will increase with age; the life span of *Apc*^Min/+^ mouse is approximately 24 weeks because of bleeding caused anemia from intestinal polyps and other factors.^([@B18]--[@B20])^ We noticed the presence of numerous PP when the mice have few polyps in the small intestine, we sought to examine the correlation between the number of polyps and PP. Previous reports have shown that the number of PP in the intestines is increased when mice are fed CHAX and/or short chain fructooligosaccharide diet.^([@B21],[@B22])^ However, there were no reports that described this change in PP levels in detail.
Our findings show that intestinal polyp formation in *Aly*^−/−^*Apc*^Min/+^ mice is lower in comparison with *Apc*^Min/+^ mice. *Aly*^−/−^ mice are created by a point mutation in the tumor necrosis factor receptor associated factor (TRAF) binding domain, which is in the *nuclear factor-κB (NF-κB)-inducing* kinase (*Nik*) gene.^([@B13])^ *NF-κB* is involved in many physiological phenomena such as acute and a chronic inflammation reactions, cell growth, and apoptosis. Furthermore, in many cases, *NF-κB* is activated in malignant tumors. Therefore, the decreased number of intestinal polyps in *Aly*^−/−^*Apc*^Min/+^ mice compared to *Apc*^Min/+^ mice may be because of the TRAF family, which have tumor promoting properties, not binding Nik.^([@B23],[@B24])^
We examined changes in immunoassociated cytokines using cytokine array, because PP are critical organs in intestinal immunity and may be involved in intestinal polyp formation. In this study, we focused on IL-17, which increased the number of PP in intestine; the levels of IL-1β remained unchanged in WT mice. IL-5 and IL-10 were excluded from analysis because the changes in concentration were only observed in *Aly*^−/−^*Apc*^Min/+^ mice that do not develop PP. IL-17 is known to be produced by T helper 17 cells (Th17) cells and plays an important role in allergic responses, such as contact hypersensitivity, delayed hypersensitivity, and airway hyper-reactivity, as determined by IL-17 gene knockout mouse studies.^([@B25])^ We found an inverse correlation existed between IL-17 concentration and the number of PP, suggesting a relationship between IL-17 and the number of PP. Although the reason of this phenomenon is not known in detail, Hirota *et al.*^([@B26])^ reported that expression of IL-17 decreases when Th17 cells induce B cell formation in PP.
Short chain fatty acids, such as sodium butyrate, are mainly produced by intestinal bacteria, and are largely involved in differentiation and nutrition of intestinal epithelial cells.^([@B27]--[@B29])^ Our cytokine array revealed that IL-17 levels were low (Table [4](#T4){ref-type="table"}). Moreover, our results demonstrate a role for IL-17 in the enhancement of Wnt signal in the intestine. There are several reports highlighting that IL-17 is involved in intestinal polyp formation in *Apc*^Min/+^ mice or it can aggravate inflammatory bowel disease.^([@B30]--[@B32])^ These findings support the hypothesis that the number of intestinal polyps is decreased due to an increase in PP in *Apc*^Min/+^ mice fed CHAX. Moreover, reduced expression of IL-17 in serum possibly causes destabilization of Wnt signaling. In the future, we propose that quantification of intestinal PP will be a useful tool for the prevention of tumorigenesis.
The authors thank K. Ogawa and Y. Kimoto (NIHON SHOKUHIN KAKO CO., LTD) for the gift of CHAX. This study was funded by a Grant-in-Aid for Challenging Exploratory Research from the Ministry of Education Culture, Sports, Science, and Technology of Japan.
Conflict of interest
====================
No potential conflicts of interest were disclosed.
{#F1}
{#F2}
{#F3}
{#F4}
{#F5}
{#F6}
######
The number of PP in*Apc*^Min/+^ mice fed CHAX
CHAX dosage (%) Small intestine
----------------- ----------------- --------------- ----------- -----------------
0 2.8 ± 0.3 1.6 ± 0.2 3.4 ± 0.2 7.8 ± 0.3
0.1 3.0 ± 0.2 2.3 ± 0.2\* 3.9 ± 0.3 9.3 ± 0.3\*\*
1 2.9 ± 0.2 2.8 ± 0.3\*\* 3.8 ± 0.3 9.5 ± 0.2\*\*\*
Values are mean ± SEM (*n* = 12/group). \**p*\<0.05, \*\**p*\<0.01, \*\*\**p*\<0.001; Mann--Whitney *t* test.
######
The number of intestinal polyps in 12-week-old *Apc*^Min/+^ mice
CHAX dosage (%) Small intestine Large intestine Total
----------------- ----------------- ----------------- -------------- ---------------- ----------- ----------------
0 3.9 ± 0.7 22.3 ± 2.2 27.2 ± 2.7 53.4 ± 4.4 0.5 ± 0.2 53.8 ± 4.3
0.1 2.1 ± 0.5 11.0 ± 1.6\*\* 16.2 ± 2.3\* 29.3 ± 3.8\*\* 0.3 ± 0.2 29.6 ± 3.9\*\*
1 3.0 ± 0.4 10.0 ± 1.7\*\* 17.9 ± 2.5\* 30.9 ± 3.3\*\* 0.4 ± 0.2 31.3 ± 3.4\*\*
Values are mean ± SEM (*n* = 12/group). \**p*\<0.05, \*\**p*\<0.01, \*\*\**p*\<0.001; Mann--Whitney *t* test.
######
The number of intestinal polyps in 12-week-old *Aly*^−/−^*Apc*^Min/+^ mice (negative control group)
CHAX dosage (%) Small Intestine Large intestine Total
----------------- ----------------- ----------------- ------------ ------------ ----------- ------------
0 4.3 ± 2.9 13.7 ± 1.6 11.3 ± 1.4 29.3 ± 2.9 0.2 ± 0.1 29.6 ± 3.0
0.1 2.0 ± 0.3 8.4 ± 1.6 10.6 ± 2.8 21.1 ± 3.7 0.1 ± 0.1 21.1 ± 3.7
1 3.4 ± 0.9 11.1 ± 3.2 11.3 ± 2.7 25.8 ± 5.9 0 25.8 ± 5.9
Values are mean ± SEM (*n* = 10/group).
######
Serum cytokine levels in WT, *Apc*^Min/+^ and *Aly*^−/−^*Apc*^Min/+^ mice fed with or without CHAX
WT mice Rate of change *Apc*^Min/+^ mice Rate of change *Aly*^−/−^*Apc*^Min/+^ mice Rate of change
--------------- --------- ---------------- ------------------- ---------------- ----------------------------- ---------------- -------- -------- ------
IL-1β (pg/ml) \<0.64 \<0.64 --- 4.38 \<0.64 6.84 \<0.64 \<0.64 --
IL-5 (pg/ml) 10.68 4.37 2.44 8.58 7.11 1.21 22.64 129.94 5.74
IL-10 (pg/ml) 3.47 7.55 2.18 4.87 4.87 1 4.18 17.56 4.2
IL-17 (pg/ml) 3.86 1.05 3.68 3.24 0.93 3.48 \<0.64 \<0.64 ---
The values are averages of extracted cytokines from double experiments of the cytokine array.
| 2023-11-12T01:26:59.872264 | https://example.com/article/4330 |
Games
PS VR compatible games selection
You’ll find below some of the games that you’ll be able to play with the 3dRudder for PlayStation VR. This list is not exhaustive. More games will progressively be added as their integration is completed or their publishers make their games public. | 2024-02-22T01:26:59.872264 | https://example.com/article/4375 |
It is recommended to compile with --arch=x86_64 to use mscoff (the windows linker). You can add "dflags-windows-x86": ["-m32mscoff"] to your application's dub.json and compile with the --arch=x86 dub option to force the windows linker on x86 applications. However, you must compile the 32mscoff druntime/phobos libraries manually and place them in C:\D\dmd2\windows\lib32mscoff. You can compile them by using BUILD=32mscoff in win64.mak and changing the library paths to 32 bit windows kits.
Your copy of DMD must be installed with visual studio on the computer to have the microsoft linker automatically configured. This configuration is located in C:\D\dmd2\windows\bin\sc.ini by default.
If you compile with optlink OMF (the DMD linker used by default on x86 builds) you will need to convert the missing DLL headers into OMF import libraries manually, using implib. | 2024-05-14T01:26:59.872264 | https://example.com/article/8600 |
Goma, Democratic Republic of Congo (CNN) -- In a remote, rural area of the Democratic Republic of the Congo (DRC), the Dian Fossey Gorilla Fund has opened the country's first rehabilitation center for Grauer's gorillas.
Called GRACE (Gorilla Rehabilitation and Conservation Education), the center's goal is to teach orphaned gorillas how to survive in the wild as a new, self-sufficient "family," with the longer-term goal to release them into a natural habitat in a neighboring forest in the Congo Basin.
These young gorillas are physically and emotionally fragile, most having suffered from extremely traumatic conditions and experiences. Many have been violently taken from the forest by poachers, intent on selling them either as bush meat or for the animal trafficking trade.
CNN's Jessica Ellis and Ferre Dollar recently followed the first group of gorillas to be transported to the forested area from a temporary facility in Goma, in eastern DRC.
The pioneering young orphans were airlifted to GRACE by a helicopter donated by MONUC, the United Nations peacekeeping force in the DRC -- a first for a U.N. mission. Traveling by road would have been almost impossible due to poor infrastructure and potential trauma to the animals.
Mapendo, Amani, Kighoma and Ndjingala were all originally snatched from the forest and their families by poachers. They are all Grauer's gorillas, a subspecies related to the Mountain gorilla, but live exclusively in eastern DRC.
Sandy Jones is the confiscated gorilla rehabilitation manager for the Dian Fossey Fund and now the manager of GRACE. "All of the gorilla species are endangered because Congo is so unexplored they have not done a real census on how many Grauer's gorillas there are," she says.
"But at the rate at which we know they are being killed and the forest is being destroyed we are really concerned that if things aren't stopped and changed now they can be wiped out very soon."
This freshman class of GRACE gorillas range in age from between one and five years old. Mapendo, whose name means "love," was rescued in December 2007. She was confiscated along with a male gorilla but he only survived for two days.
When Amani -- which means "peace" -- was rescued a year ago she had a large wound on her leg. "It seemed obvious that her mother was shot and she was caught in the crossfire," Jones explains. "It took many weeks to heal but now she is walking perfectly normal."
Kighoma -- "drums" -- is the only male in the group. He arrived in May 2009, and Ndjingala was rescued earlier this year. She is only a year old and was named after the place from which she was taken.
"A lot of primates, when they are taken by poachers, they have ropes around their hips and it digs in and so they have bad wounds and Ndjingala suffered from that," Jones says.
The Dian Fossey gorilla fund and the Mountain Gorilla Veterinary Project have been caring for rescued gorillas in temporary quarters in Kinigi, in Rwanda, and in Goma.
"What I know is that many of them have died," says Dr. Eddie Kambale of the Mountain Gorilla Veterinary Project. "We may have, I can say, about 20% that have been taken from the forest."
The GRACE center is the first facility of its kind in east Central Africa. It has room for up to 30 young gorillas to live in species-typical groups and roam through 350 acres of natural habitat.
Kambale helped bring the four orphans from Goma to GRACE. "The gorillas are enjoying this place compared to where they were," he says.
"In Goma there was too much noise and dust from the road; here is less pollution so this will be good for their health. Now they are in the real forest and they are climbing and getting some forest food, so they are happy."
The remaining rescued Grauer's gorillas currently cared for by the Dian Fossey Fund and Mountain Gorilla Veterinary Project will leave Kinigi on a second airlift scheduled for early next year.
"Having the gorillas here will help give the people a glimpse of the world of gorillas," says Debby Cox, of the Pan African Sanctuary Alliance.
Cox worked with the local community to build the infrastructure for GRACE. "When the local people see gorillas as so much like us -- they live in families, the infants need their mothers, they hug each other -- you immediately get an empathy coming," she says.
"So we need to work with the people in this area, and that helps create stability and that creates confidence too."
While for decades the world has only heard bad news from the Democratic Republic of the Congo, conservation is striking an increasingly important chord of awareness among the people. | 2024-05-05T01:26:59.872264 | https://example.com/article/2061 |
Daily life therapy: a Japanese model for educating children with autism.
The controversial practice of Daily Life Therapy, as demonstrated at the Boston Higashi School in Massachusetts, is reviewed. Five fundamental principles of Daily Life Therapy are examined: instruction that is group-oriented; routine activities that are highly structured; instructional techniques that center on learning through imitation; a method for reducing children's levels of unproductive activity through rigorous physical exercise; and a curriculum that focuses on movement, music, and art. These central features of Daily Life Therapy are discussed in light of current theory, research, and educational practices in autism. Empirical questions raised by this unique treatment mode are outlined. | 2023-11-12T01:26:59.872264 | https://example.com/article/4747 |
Glass and silicon oxide are widely used substrates for biosensors, clinical immunoassay diagnostics, and cell culture (Ratner, Schoen et al. 1996) and as solid supports for the synthesis of peptides, carbohydrates, and DNA (Seeberger and Haase 2000). The modification of silicon oxide to modulate protein and cell interactions has proven to challenging for a number of technical reasons: 1) the formation of silane self-assembled monolayers (SAMs), the most common route to functionalize glass and other metal oxides, is complicated by the sensitivity of most silanes to humidity and their propensity to form polymeric multi-layers (Wasserman, Tao et al. 1989; Ulman 1996). 2) As is typical to most “grafting to” approaches, the passivation of silicon oxide by grafting polyethylene glycol (PEG) to the surface using silane chemistry (Emoto, Harris et al. 1996; Yang, Galloway et al. 1999) does not provide a high surface density of PEG due to the excluded volume effect (Knoll and Hermans 1983). Consequently, grafted PEG coatings on glass decrease the adsorption of proteins, but do not reduce their adsorption below the nominal limit of several ng/cm2 (Zhu, Jun et al. 2001). Several approaches such as the sequential grafting of PEGs of different chain lengths (Nagasaki, Ishii et al. 2001) and cloud-point grafting of PEG (Kingshott, Thissen et al. 2002) have been taken to solve this problem, but only with limited success. 3) It is also difficult to stamp silanes onto glass with the ease and reproducibility with which alkanethiols can be patterned by micro-contact printing and other soft lithography methods so that the patterning of PEG on to glass by soft lithography has only been marginally successful (Xia, Mrksich et al. 1995; StJohn and Craighead 1996).
For the detection of a variety of biological molecules such as protein, RNA, and DNA in complex biological fluids, the minimization of non-specific protein binding plays a very important in improving the detection limit and sensitivity. The reduction of adsorption of protein and other biomolecules is important for the development of interfacial sensors for two reasons: first, for the broad class of sensors that are label-free, i.e., in which the binding event is directly transduced as the detected signal (e.g., surface plasmon resonance (SPR) spectroscopy, localized or nanoparticle-based surface plasmon resonance (nanoSPR), surface enhanced Raman scattering (SERS), ellipsometry, gravimetric sensors such as quartz-crystal microbalance dissipation (QCM-D) and surface acoustic wave (SAW) sensors, etc.) reduction of protein adsorption to ultra-low levels (<1 ng/sq. cm) is critical to generate a high signal-to-noise ratio (SNR) by reducing the noise due to adventitious adsorption. For the class of interfacial sensors that use a label to generate the detected signal, the elimination of background adsorption is similarly important to reduce noise. Finally, for the class of sensors that incorporate an amplification step prior to or during generation of the detected signal, the effective elimination of adventitious adsorption or binding of biomolecules or other reagents is critical, as adventitiously bound molecules can be amplified, so that the increase in signal (S) afforded by the amplification step is in many cases compromised by the concomitant amplification of the background noise (N), so that the gains in SNR are modest, at best.
The increasing technological push towards ultra-sensitive detection in biomolecular arrays—DNA, protein and carbohydrate—similarly requires extremely low background signals so that a high SNR can be attained (Zhu and Snyder 2003). However, most commercially available chemical surface modifications usually have high auto-fluorescence or non-specific binding of reagents and analytes. This issue is increasingly crucial when the spot size of commonly used microarrays becomes smaller and smaller, even down to the sub-micron length scale. Although some of the current surface modification techniques work well for microarrays (Zhu and Snyder 2003), the routine use of micro- and nano-arrays for biomolecules still poses substantial challenges in engineering a detection system that is capable of resisting non-specific adsorption of biomolecules down to the pg/cm2 level and allows direct detection of analytes without elaborate and expensive amplification techniques. | 2023-08-16T01:26:59.872264 | https://example.com/article/7068 |
Movie Marathon
Tuesday, November 03, 2009
jeffrey siy
1 Comments
Last week was probably the most number of movies I watched for FREE. I got to see More than a Game, 500 Days of Summer, Astro Boy, and This is It! Each movie caters to a different kind of audience. Have a son aspiring to be the next NBA star? - go watch More than a Game! Are you with your GF/BF or BFF? - 500 Days of Summer is your flick. Want to watch an educational and fun movie with your kid? - Astro Boy is the movie to watch. Still can't get enough of the life of MJ? - see This is It!
Email & Win Posters - SM Cinema website
I don't want to ruin the movie for you so I'll just give you a couple of points about these 4 movies
More than a Game
A documentary about NBA superstar LeBron James and four of his teammates in High School
Triumph, failure and everything in between
My Rating: 4.5/5
500 Days of Summer
This is definitely not another love story. It will leave you thinking of what love really is
Good cinematography, good actors, great story... at least for me
My Rating: 5/5
Astro Boy
Astro Boy is a boy robot who tries to discover his purpose and identity after being discarded by the scientist that made him
1 comments:
Last week was probably the most number of movies I watched for FREE. I got to see More than a Game, 500 Days of Summer, Astro Boy, and This is It! Each movie caters to a different kind of audience. Have a son aspiring to be the next NBA star? - go watch More than a Game! Are you with your GF/BF or BFF? - 500 Days of Summer is your flick. Want to watch an educational and fun movie with your kid? - Astro Boy is the movie to watch. Still can't get enough of the life of MJ? - see This is It!
Email & Win Posters - SM Cinema website
I don't want to ruin the movie for you so I'll just give you a couple of points about these 4 movies
More than a Game
A documentary about NBA superstar LeBron James and four of his teammates in High School
Triumph, failure and everything in between
My Rating: 4.5/5
500 Days of Summer
This is definitely not another love story. It will leave you thinking of what love really is
Good cinematography, good actors, great story... at least for me
My Rating: 5/5
Astro Boy
Astro Boy is a boy robot who tries to discover his purpose and identity after being discarded by the scientist that made him
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Boy Kuripot claims no credit for any images/videos featured on this site unless otherwise noted. All visual content is copyright to it’s respectful owners(links). Boy Kuripot is in no way responsible for or has control of the content of any external web site links. Information on this site may contain errors or inaccuracies; Boy Kuripot does not make warranty as to the correctness or reliability of the site’s content. If you own rights to any of the images, and do not wish them to appear on this site, please contact Boy Kuripot via e-mail and they will be promptly removed. | 2023-09-26T01:26:59.872264 | https://example.com/article/8878 |
#!/bin/sh
set -o errtrace
set -o errexit
# Maintainer: weitao zhou <wtzhou@dataman-inc.com>
# Usage:
# curl -Ls https://$DM_HOST/node-init.sh | sudo sh
#
# Feature:
# check host arch
# check ip forwarding
# check docker version
# check docker tcp socket
# check apparmor for ubuntu
# check selinux for centos/rhel
# check ntp service
# check firewalld
# check iptables
# Suppose the major version=1
# The following represents the acturally desired version is 1.12.0
DOCKER_MINOR_VERSION_REQUIRED=12
# docker convention:
# 2376: encrypted communication
# 2375: un-encrypted communication
DOCKER_TCP_SOCKET=2375
SUPPORTED_ARCH=x86_64
_command_exists() {
command -v "$@" > /dev/null 2>&1
}
host_arch_supported()
{
if [ "$(uname -m)" != $SUPPORTED_ARCH ]; then
echo "********************************************************"
printf "\033[41mERROR:\033[0m We cannot support arch $(uname -m), and x86_64 is the only supported arch currently.\n"
echo "********************************************************"
exit 1
fi
}
ip_forwarding_enabled()
{
sysctl net.ipv4.ip_forward | grep 1 || {
echo "********************************************************"
printf "\033[41mERROR:\033[0m IP Forwarding is disabled! Please Enable the IP Forwarding permanently as following:\n"
echo "********************************************************"
printf "\n"
printf "\n"
printf "edit or add a line containing \e[1;34m net.ipv4.ip_forward=1 \e[0m to file /etc/sysctl.conf , and then,\n"
printf "run command sysctl -p /etc/sysctl.conf\n"
printf "refer: http://www.ducea.com/2006/08/01/how-to-enable-ip-forwarding-in-linux/\n"
exit 1
}
}
docker_required() {
if _command_exists dockerd; then
echo "-> Checking docker runtime environment..."
else
echo "********************************************************"
printf "\033[41mERROR:\033[0m command **dockerd** is NOT FOUND! Please make sure docker-engine>=1.$DOCKER_MINOR_VERSION_REQUIRED is installed!\n"
echo "********************************************************"
exit 1
fi
docker_version="$(docker version --format '{{.Server.Version}}' | awk -F. '{print $2}')"
if [ -z $docker_version ];then
echo "***********************************************************************"
printf "\033[41mERROR:\033[0m Docker daemon is NOT STARTED! Run it manually:\n"
printf "\n"
printf "\n"
printf "For CentOS/RHEL\n"
printf "systemctl enable docker && service docker start\n"
printf "refer: https://docs.docker.com/engine/installation/linux/centos/#/start-the-docker-daemon-at-boot\n"
printf "\n"
printf "For Ubuntu>=15.04\n"
printf "systemctl enable docker && service docker start\n"
printf "\n"
printf "For Ubuntu<=14.10\n"
printf "service docker start\n"
printf "refer: https://docs.docker.com/engine/installation/linux/ubuntulinux/#/configure-docker-to-start-on-boot\n"
echo "***********************************************************************"
exit 1
fi
if [ $docker_version -lt $DOCKER_MINOR_VERSION_REQUIRED ]; then
echo "********************************************************"
printf "\033[41mERROR:\033[0m docker-engine>=1.$DOCKER_MINOR_VERSION_REQUIRED is required, current version: 1.$docker_version\n"
echo "********************************************************"
exit 1
fi
echo "Checking docker runtime environment...DONE"
}
docker_tcp_open_required()
{
echo "-> Checking docker TCP Socket..."
DOCKER_HOST="tcp://0.0.0.0:$DOCKER_TCP_SOCKET" docker info >/dev/null 2>&1 ||
{
echo "********************************************************"
printf "\033[41mERROR:\033[0m Please enable the Docker tcp Socket on port: $DOCKER_TCP_SOCKET\n"
printf "How to configure it?\n"
printf "\n"
printf "For CentOS/RHEL(systemd)\n"
printf "Edit file /usr/lib/systemd/system/docker.service, let ExecStart=/usr/bin/dockerd -H tcp://0.0.0.0:$DOCKER_TCP_SOCKET -H unix:///var/run/docker.sock\n"
printf "Then, systemctl daemon-reload && service docker restart\n"
printf "\n"
printf "For Ubuntu(upstart)\n"
printf "Touch or edit file /etc/default/docker, let DOCKER_OPTS=\"-H tcp://0.0.0.0:$DOCKER_TCP_SOCKET -H unix:///var/run/docker.sock\"\n"
printf "Then, service docker restart\n"
printf "\n"
printf "Refer: https://docs.docker.com/engine/reference/commandline/dockerd/#/daemon-socket-option\n"
echo "********************************************************"
exit 1
}
echo "Docker TCP Socket $DOCKER_TCP_SOCKET opened...DONE"
}
iptables_docker_rules() {
echo "-> Checking docker rules on Iptables..."
if iptables -L | grep "DOCKER" > /dev/null; then
if iptables -L | grep "REJECT" > /dev/null; then
printf "\033[41mERROR:\033[0m Some REJECT rules found in iptables, which may cause undesired exceptions, to continue, please remove the REJECT rules and restart Iptables service.\n"
printf "One way to delete iptables rules is by its chain and line number. To determine a rule's line number, list the rules in the table format and add the --line-numbers option:\n"
printf "\n"
printf "iptables -L --line-numbers\n"
printf "\n"
printf "\tChain INPUT (policy DROP)\n"
printf "\tnum target prot opt source destination\n"
printf "\t1 ACCEPT all -- anywhere anywhere ctstate RELATED,ESTABLISHED\n"
printf "\t2 DROP all -- anywhere anywhere ctstate INVALID\n"
printf "\t3 REJECT udp -- anywhere anywhere reject-with icmp-port-unreachable\n"
printf "Once you know which rule you want to delete, note the chain and line number of the rule. Then run the iptables -D command followed by the chain and rule number. For example:\n"
printf "\n"
printf "iptables -D INPUT 3\n"
printf "\n"
exit 1
fi
else
printf "\033[41mERROR:\033[0m Please make sure iptables nat is open.\n"
echo "Learn more: https://dataman.kf5.com/posts/view/124302/"
exit 1
fi
echo "Checking docker rules on Iptables...DONE"
}
apparmor_required_on_ubuntu()
{
/etc/init.d/apparmor status >/dev/null 2>&1 ||
{
echo "********************************************************"
printf "\033[41mERROR:\033[0m Exception triggered when run \e[1;34m /etc/init.d/apparmor status \e[0m ! Please install apparmor as following:\n"
echo "********************************************************"
printf "\n"
printf "\n"
printf "apt-get install -y apparmor apparmor-utils\n"
exit 1
}
}
# Firewalld on CentOS/RHEL caused docker issue maybe: https://github.com/docker/docker/issues/16137
# https://docs.docker.com/v1.6/installation/centos/#firewalld
firewalld_is_enabled() {
echo "-> Checking firewalld..."
if ps ax | grep -v grep | grep "firewall" > /dev/null; then
printf "\e[1;34mWARN:\e[0m You'd better to disable Firewalld&enable iptables, or must restart docker daemon after firewalld restarted.\n"
echo "More info: https://docs.docker.com/v1.6/installation/centos/#firewalld"
echo "More info: https://github.com/docker/docker/issues/16137"
echo "you can run systemctl disable firewalld && systemctl stop firewalld"
exit 1
fi
}
selinux_is_disabled() {
if _command_exists getenforce; then
echo "-> Checking SELinux by command getenforce..."
if getenforce | grep -v "Enforcing" > /dev/null; then
echo "SELinux has been stopped as desired."
else
printf "\033[41mERROR:\033[0m We'd better to disable SELinux.\n"
printf "\n"
printf "How to disable it?\n"
printf "Set SELINUX=disabled in file /etc/sysconfig/selinux for permanent effect"
echo "setenforce 0 && sed -i 's/SELINUX=.*/SELINUX=disabled/g' /etc/selinux/config"
echo "Learn more: https://dataman.kf5.com/posts/view/124303/"
exit 1
fi
else
printf "\033[41mERROR:\033[0m Command \033[1mgetenforce\033[0m not found\n"
exit 1
fi
}
ntp_is_enabled_on_centos_or_rhel()
{
if _command_exists ntpstat; then
echo "-> Checking NTP service status..."
ntpstat ||
{
printf "\033[41mERROR:\033[0m NTP is unsynchronised, Please confirm your ntp status before continue.\n"
exit 1
}
echo "NTP service status seems good...DONE"
else
printf "\033[41mERROR:\033[0m Cannot find the command ntpstat, Please enable the NTP service on your node.\n"
printf "You can run yum install -y ntp && systemctl start ntpd && systemctl enable ntpd && systemctl disable chronyd \n"
exit 1
fi
}
ntp_is_enabled_on_ubuntu()
{
if _command_exists ntpq; then
echo "-> Checking NTP service status..."
# TODO: weird method to check the ntp status
ntpq -p | grep -Fq offset ||
{
printf "\033[41mERROR:\033[0m NTP is unsynchronised, Please confirm your ntp status before continue.\n"
exit 1
}
echo "NTP service status seems good...DONE"
else
printf "\033[41mERROR:\033[0m Cannot find the command ntpstat, Please enable the NTP service on your node.\n"
exit 1
fi
}
get_distribution_type()
{
local lsb_dist
lsb_dist=''
if _command_exists lsb_release; then
lsb_dist="$(lsb_release -si)"
fi
if [ -z "$lsb_dist" ] && [ -r /etc/lsb-release ]; then
lsb_dist="$(. /etc/lsb-release && echo "$DISTRIB_ID")"
fi
if [ -z "$lsb_dist" ] && [ -r /etc/debian_version ]; then
lsb_dist='debian'
fi
if [ -z "$lsb_dist" ] && [ -r /etc/fedora-release ]; then
lsb_dist='fedora'
fi
if [ -z "$lsb_dist" ] && [ -r /etc/os-release ]; then
lsb_dist="$(. /etc/os-release && echo "$ID")"
fi
if [ -z "$lsb_dist" ] && [ -r /etc/centos-release ]; then
lsb_dist="$(cat /etc/*-release | head -n1 | cut -d " " -f1)"
fi
if [ -z "$lsb_dist" ] && [ -r /etc/redhat-release ]; then
lsb_dist="$(cat /etc/*-release | head -n1 | cut -d " " -f1)"
fi
lsb_dist="$(echo $lsb_dist | cut -d " " -f1)"
lsb_dist="$(echo "$lsb_dist" | tr '[:upper:]' '[:lower:]')"
echo $lsb_dist
}
lsb_version=""
have_a_init()
{
host_arch_supported
ip_forwarding_enabled
docker_required
docker_tcp_open_required
case "$(get_distribution_type)" in
gentoo|boot2docker|amzn|linuxmint)
(
echo "$(get_distribution_type) is unsupported."
)
exit 1
;;
fedora|centos|rhel|redhatenterpriseserver)
(
if [ -r /etc/os-release ]; then
lsb_version="$(. /etc/os-release && echo "$VERSION_ID")"
if [ $lsb_version '<' 7 ]
then
printf "\033[41mERROR:\033[0m CentOS-$(lsb_version) is unsupported\n"
exit 1
fi
else
printf "\033[41mERROR:\033[0m File /etc/os-release not found, so the CentOS version cannot be confirmed.\n"
exit 1
fi
if _command_exists firewall-cmd; then
firewalld_is_enabled
fi
if _command_exists iptables; then
iptables_docker_rules
else
printf "\033[41mERROR:\033[0m Command iptables does not exists.\n"
exit 1
fi
selinux_is_disabled
ntp_is_enabled_on_centos_or_rhel
)
exit 0
;;
sles|suse)
(
selinux_is_disabled
)
exit 0
;;
ubuntu|debian)
(
apparmor_required_on_ubuntu
ntp_is_enabled_on_ubuntu
)
exit 0
;;
*)
printf "\033[41mERROR\033[0m Unknown operating system.\n"
echo "Learn more: https://dataman.kf5.com/posts/view/131402"
;;
esac
}
# wrapped up in a function so that we have some protection against only getting
# half the file during "curl | sh"
have_a_init
| 2024-02-11T01:26:59.872264 | https://example.com/article/1584 |
Lamar Johnson, who is serving his 25th year in prison, has been absolved of responsibility for a 1994 murder. A circuit judge says it's too late to give him a new trial.
Lamar Johnson is serving his 25th year in prison for a murder he almost certainly didn't commit. On Monday, 45 prosecutors asked the Missouri Supreme Court to grant Johnson a new trial.
As Reasonpreviously reported, Johnson was convicted of the 1994 murder of Marcus Boyd. In order for Johnson to have actually killed Boyd, he would have needed to leave an apartment party, travel three miles to commit the murder, and return to the apartment on foot all within the span of five minutes. While this is beyond the realm of possibility, Johnson's case was doomed by investigative fabrication, perjured testimony, the suppression of exculpatory evidence, and an unreliable jailhouse informant. One of the men responsible for his conviction was lead detective Joseph Nickerson, who falsified four witness statements and even offered a man a $4,000 bribe to identify Johnson as the killer.
The actual killers not only confessed to the murder but absolved Johnson of involvement. Still, Johnson sits in prison. The Midwest Innocence Project has taken his case on.
St. Louis Circuit Attorney Kim Gardner, who stands by Johnson's innocence, filed a motion for a new trial in July 2019. Circuit Judge Elizabeth B. Hogan ruled against the motion just one month later, saying that it was 24 years too late. Hogan stood by a court rule that only allowed for a motion for a new trial to be scheduled within 15 days of a conviction.
On Monday, 45 prosecutors filed an amicus brief, available here, in support of Gardner's efforts. They've asked the trial court toreverse its August decision.
The prosecutors expressed concern that the court stopped Gardner from retrying the case because of procedural deadlines. The prosecutors maintain that waiving such a deadline falls within the realm of Gardner's discretion and add they are "deeply troubled" by the court's conclusion that Gardner has no power to remedy a false conviction.
"The incarceration of an innocent person at the hands of his own government is an intolerable event," reads the brief. "When an innocent person becomes enmeshed in the gears of that system, the officials empowered by the public to turn on the machinery are not powerless to turn it off."
Unfortunately, the prosecutors advocating for Johnson face another obstacle. A proposed law in the state legislature seeks to give Missouri's attorney general the power to take over cases where local prosecutors refuse to file charges. The bill was proposed, in part, because of St. Louis County Prosecuting Attorney Wesley Bell, whose name appears on the Monday brief. Like Gardner, Bell is visibly attempting to reform the county's criminal justice system by exercising prosecutorial discretion in cases.
If passed, the attorney general would be empowered to prosecute cases where local prosecutors have already decided charges would be unduly harsh or wasteful to taxpayers.
There is already tension between the local prosecutors and Attorney General Eric Schmitt, considering he was appointed by the trial court to serve as a prosecutor alongside Gardner in Johnson's legal proceedings. Schmitt is opposed to retrying Johnson's case because of the procedural deadline and there are no clear boundaries between Schmitt and Gardner's duties on the case.
The brief further asks the Missouri Supreme Court to allow Gardner alone to serve as the prosecutor in the case. The prosecutors argued that the attorney general did not have the jurisdiction, nor any legitimate reason allowed by state law, to be appointed.
Miriam Krinsky, executive director of Fair and Just Prosecution, the organization that put the brief together, has criticized the attorney general's "insertion" in Gardner's case, saying it undermines prosecutorial discretion. "Further, it reeks of a politically motivated attempt to seize power from the hands of a prosecutor who has rejected the continued criminalization of low-income people and people of color, and is focused on moving away from past failed 'tough on crime' practices and building healthier and safer communities with proven evidence-based policies," she said in a press release.
Krinsky tells Reason that the attorney general's presence both undermines "the obligation of local prosecutors" to fix wrongful convictions and the wishes of voters who elected Gardner to her position. Krinsky also says Johnson's case raises "the question of whether justice has an expiration date."
Editor's Note: We invite comments and request that they be civil and on-topic. We do not moderate or assume any responsibility for comments, which are owned by the readers who post them. Comments do not represent the views of Reason.com or Reason Foundation. We reserve the right to delete any comment for any reason at any time. Report abuses.
And these are the apparatchiks we are supposed to trust with telling businesses what to do, running health care, and everything else under the sun.
I understand why Bernie, Lizzie, and even AOC are so blind — they think they have a good shot at running things. Why do so many voters vote for them, when they haven;t got a chance in hell of being in charge?
As Reason previously reported, Johnson was convicted of the 1994 murder of Marcus Boyd. In order for Johnson to have actually killed Boyd, he would have needed to leave an apartment party, travel three miles to commit the murder, and return to the apartment on foot all within the span of five minutes. … The actual killers not only confessed to the murder but absolved Johnson of involvement.
Finally! A case where it’s not only absolutely clear that the accused likely didn’t commit the crime, but the entire counter case doesn’t have to be fabricated whole cloth from untested, 30-yr.-old trace DNA.
I was beginning to have faith that really weren’t any innocent men sitting in prison waiting for our justice system to fail to exonerate them.
Basically, dope dealer and otherwise ‘repeat offender’ gets wrongfully accused of killing his prior business associate and then minor business rival. Cops get other people involved to perjure themselves so that they can clear the case. The motion for a new trial has the closest thing to a decent Statement of Facts that I can find in any of the appellate opinions; most of which deal with procedural wrangling about if the trial court could grant a new trial, and whether appointing the state AG’s office sua sponte was kosher or not.
The guy probably needs a pardon or commutation, and indeed, one of the lower appellate courts suggests just that.
“That said, commute his sentence already. It doesn’t look like he was guilty of this crime.”
That’s mighty fuckin’ white of you. How about a pardon instead. You want to empathize with a politician over his unwillingness to do the right thing (justice) because of an election. Are you lost? Forty-five prosecutors are on his side. Think about that.
Oh, because you got your jack boot cop thinking cap on, amirite? Because “…Mr. Johnson was himself a retail level illegal drug dealer, and classified as a repeat offender.” And everyone knows that drug dealers in disputes are ipso facto murderers waiting to happen.
First, I’m sure R Mac was being sarcastic. And is probably closer to your point of view on this case than you think.
Second, what mattered in this case was that Mr. Johnson was himself a retail level illegal drug dealer, and classified as a repeat offender. Further the police talked to witnesses who told them that Johnson was acquainted with the deceased, was in the same line of work, and also that he had a dispute with the victim. It’s not like the cops pulled this guy’s name out of a hat, or crashed college parties til they found a black guy to hang this case on.
It looks like they suborned perjury, and that the prosecutors violated Brady. It also looks like Johnson didn’t commit this particular crime.
Shrug. The Innocence Project actually finds a guy that didn’t do it, every once in a while.
I think it’s hilarious that you bring up ‘Hurricane’ Carter, given it’s more likely than not that he and his friend actually did those murders. Go read more about the case besides that execrable movie from Norman Jewison, or Bob Dylan’s song, and consider the sheer number of coincidences that would have had to happen for Carter to not have been involved. Same car as the killers, with same color, same color trim, same exotic taillights, out of state plates on the car, like the killers. All of this around 3 in the morning by the way, when the streets were just filled with traffic… Anyway, same caliber of ammunition (.32 and 12 gauge) the killers used rolling around inside the car. Witness description and sketch from same that resembled his accomplice, Artis. The same accomplice who was reported as wanting to get back at white people, as a white man had shot a relative of his earlier. No attempt to rob the all white victims.
No wonder two separate trial juries convicted. Yes, there likely was a Brady violation in not disclosing the deal the prosecution cut with the two burglars who were the star witnesses.
Carter was the Mumia Jamal of his day. And he had the great good fortune to be a violent shithead—with numerous violent crimes he was convicted of besides the murders at the Lafayette Bar and Grill—who was also an excellent athlete. And who became a lefty cause celebre because it allowed said lefties to decry racism. He found a federal judge who bought his story, and the DA didn’t feel like trying a 20 year old murder case for the third time.
Returning to Johnson, a retail crack dealer, who was noted as a repeat offender. Yet neither the Innocence Project, nor the States Motion to overturn his conviction, cared to go into detail about said criminal history. Which doesn’t help me think it was the ‘non-violent’ drug criminal that Reason so loves to talk about, No, I’m not going to cry that a crack dealer in the early 1990s caught a case for something he didn’t do. As opposed to catching a case for all of the violent stuff attendant with being a retail crack dealer that he didn’t get caught for.
As I wrote above, he deserves a pardon or commutation, as I think he wasn’t proven beyond a reasonable doubt to have committed the murder of Marcus Boyd.
I am creating an honest wage from home 4000 Dollars/week , that is wonderful, below a year agone i used to be unemployed during a atrocious economy. I convey God on a daily basis i used to be endowed these directions and currently it’s my duty to pay it forward and share it with everybody, Here is I started……. ….. Read More
Of course, in the minds of many judges, prosecutors, and conservatives, justice has an expiration date. Supreme Court [In]Justice Scalia often wrote about the “importance of finality” of judgments, an importance which, to him, surpassed concerns for justice. Scalia thought the “justice system” simply had to move on at some point, and end “endless appeals,” even if innocent persons had been convicted. | 2023-08-09T01:26:59.872264 | https://example.com/article/8621 |
1. Field of the Invention
This invention pertains to the field of urethane-modified polyisocyanurate rigid foams. More particularly, this invention pertains to the use of specific polyols utilized in preparing said foams.
2. Description of the Prior Art
Urethane-modified polyisocyanurate rigid foams are known in the art. Such foams are prepared by reacting a polyol, polyisocyanate and optionally other ingredients in the presence of a blowing agent. An isocyanurate group formation catalyst is used to trimerize the isocyanate groups to form the isocyanurate linkages. The polyol essentially acts as a modifying or reactive plasticizing agent in the overall polymeric scheme since a polymer containing only isocyanurate groups is itself too friable. Thus, the isocyanurate foam contains both isocyanurate groups, as well as urethane linkages, with said urethane linkages acting to plasticize the foam. Initially, the reaction proceeds to give a urethane quasi-prepolymer containing active isocyanate groups which during the subsequent reaction time, trimerize to give A polymer rich in isocyanurate linkages. This sequence ultimately produces a urethane-modified polyisocyanurate polymer.
Some main uses of the resultant foam include those of thermal insulation, and as building materials and the like. Examples of some prior art, isocyanurate foams and methods of preparation are described in U.S. Pat. Nos. 3,745,133; 3,644,232; 3,676,380; 3,168,483; and 3,519,950 to name a few.
However, many known polyisocyanurate foams have one or more disadvantages. In particular, rigid foams of this type often have high friability or propensity to break. Efforts to reduce friability have often resulted in sacrifice of dimensional stability, and thermal stability and flammability resistance. Lack of flammability resistance is particularly characterized by flame spreadability. Yet other prior art polyisocyanurate foams have suffered from disadvantages of low adhesiveness, irregular cell structure and the like.
One class of polyols disclosed as being useful in preparing polyisocyanurates are novolak resins or derivatives of novolak resins, including, alkoxylated novolak resins. See, for example, U.S. Pat. Nos. 3,723,364; 3,723,367; 3,728,293; 3,745,133; 3,842,036; and 3,849,349. In each instance, the novolak resin is prepared by reacting an excess of phenolic compound such as phenol itself with an aldehyde such as formaldehyde. The excess aromatic phenol is then removed and the resin used as such or derivatized, such as by preparing an oxyalkylated phenol-aldehyde resin. However, it has been found here that such novolak polyols, while useful in preparing rigid polyisocyanurate foams, nevertheless, still do not have the requisite degree of low friability necessary for a commercial application.
We have now found that it is now possible to prepare modified polyisocyanurate foams involving use of specific novolak polyols that do not exhibit any of the aforesaid disadvantages. We have particularly found that urethane-modified polyisocyanurate foams can be prepared having suitable dimensional stability, low friability and good flammability resistance. Such are achieved without sacrifice of other sought-after properties such as thermal stability. | 2023-12-24T01:26:59.872264 | https://example.com/article/2464 |
[Morphometric cellular characteristics of the inflammatory infiltrate in nonirradiated and irradiated rectal cancer].
A morphometric analysis of the inflammatory infiltrate cells of the stroma and adjacent tissue of adenocarcinomas of the rectum was performed in 40 patients. As to therapeutic modality, the patients were divided into 4 groups of 10 patients in each. The 1st group was given surgery only, the 2nd group preoperative gamma-therapy at a dose of 19.5 Gy, the 3rd 30 Gy and the 4th 40 Gy. Integral fractions of lymphocytes, plasmocytes and eosinophils were determined on randomly selected sections using the point counting technique. It was shown that in adenocarcinomas of the rectum integral fractions of the above cells had similar values irrespective of tumor macroscopic shape, degree of differentiation and growth depth. Cellular reactions in the adjacent tissues were more noticeable than in tumor itself, and numerical values of the integral fractions of inflammatory infiltrate cells depended on growth depth. After irradiation a decrease in the lymphocyte integral fraction and an increase in the plasmocyte integral fraction were noted both in the stroma and adjacent tissues. | 2024-03-21T01:26:59.872264 | https://example.com/article/5725 |
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they tried to roll jonathon scott out there at one time. That sure didn't work.
I guess it was marvel before max. I hope they bring max back, as he is the best option.
Yup.. and without Starks coming back, the Steelers would have had a horrible season last year. Half of Tomlin's pay should have went to Starks because he basically saved Tomlin's butt. Tomlin would really be in the hot seat if we went all last year with Scott at LT (likely a losing season), followed by this season.
Yup.. and without Starks coming back, the Steelers would have had a horrible season last year. Half of Tomlin's pay should have went to Starks because he basically saved Tomlin's butt. Tomlin would really be in the hot seat if we went all last year with Scott at LT (likely a losing season), followed by this season.
I think the Scott fiasco may have been on Kugler. I'm am now of the opinion that Kugler was never what we thought he was. Who did he develop and really make better while he was here and he brought Scott with him from Buffalo.
I have an idea. Why not move Pouncey to guard (which many in the organization believe he could be great at), and draft C Khaled Holmes from USC? Could get Holmes in round 3. He's a solid center who has played actually at Guard as well.
But from the article, "Make no mistake about it, if Foster returns next year, Willie Colon won’t." | 2024-06-07T01:26:59.872264 | https://example.com/article/1834 |
Q:
How to solve error in installing portia
I have problems when installing portia on ubuntu 16.04
Failed building wheel for cryptography
Running setup.py clean for cryptography
Successfully built mysql-connector-python
Failed to build cryptography
Installing collected packages: cryptography, pyopenssl, pyasn1-modules,
characteristic, service-identity, requests, txaio, autobahn, chardet, monotonic, parse, ndg-httpsclient, mysql-connector-python, dulwich, qt5reactor, psutil, adblockparser, xvfbwrapper, funcparserlib, Pillow, splash
Running setup.py install for cryptography ... error
Complete output from command /home/hamadi/portiaenv/bin/python -u -c "import setuptools, tokenize;__file__='/tmp/pip-build-bhZXhZ/cryptography/setup.py';f=getattr(tokenize, 'open', open)(__file__);code=f.read().replace('\r\n', '\n');f.close();exec(compile(code, __file__, 'exec'))" install --record /tmp/pip-DseSM4-record/install-record.txt --single-version-externally-managed --compile --install-headers /home/hamadi/portiaenv/include/site/python2.7/cryptography:
running install
running build
running build_py
creating build
creating build/lib.linux-x86_64-2.7
creating build/lib.linux-x86_64-2.7/cryptography
copying src/cryptography/exceptions.py -> build/lib.linux-x86_64-2.7/cryptography
copying src/cryptography/__about__.py -> build/lib.linux-x86_64-2.7/cryptography
copying src/cryptography/utils.py -> build/lib.linux-x86_64-2.7/cryptography
copying src/cryptography/fernet.py -> build/lib.linux-x86_64-2.7/cryptography
copying src/cryptography/__init__.py -> build/lib.linux-x86_64-2.7/cryptography
creating build/lib.linux-x86_64-2.7/cryptography/x509
copying src/cryptography/x509/name.py -> build/lib.linux-x86_64-2.7/cryptography/x509
copying src/cryptography/x509/extensions.py -> build/lib.linux-x86_64-2.7/cryptography/x509
copying src/cryptography/x509/oid.py -> build/lib.linux-x86_64-2.7/cryptography/x509
copying src/cryptography/x509/general_name.py -> build/lib.linux-x86_64-2.7/cryptography/x509
copying src/cryptography/x509/__init__.py -> build/lib.linux-x86_64-2.7/cryptography/x509
copying src/cryptography/x509/base.py -> build/lib.linux-x86_64-2.7/cryptography/x509
creating build/lib.linux-x86_64-2.7/cryptography/hazmat
copying src/cryptography/hazmat/__init__.py -> build/lib.linux-x86_64-2.7/cryptography/hazmat
creating build/lib.linux-x86_64-2.7/cryptography/hazmat/bindings
copying src/cryptography/hazmat/bindings/__init__.py -> build/lib.linux-x86_64-2.7/cryptography/hazmat/bindings
creating build/lib.linux-x86_64-2.7/cryptography/hazmat/primitives
copying src/cryptography/hazmat/primitives/keywrap.py -> build/lib.linux-x86_64-2.7/cryptography/hazmat/primitives
copying src/cryptography/hazmat/primitives/hmac.py -> build/lib.linux-x86_64-2.7/cryptography/hazmat/primitives
copying src/cryptography/hazmat/primitives/hashes.py -> build/lib.linux-x86_64-2.7/cryptography/hazmat/primitives
copying src/cryptography/hazmat/primitives/cmac.py -> build/lib.linux-x86_64-2.7/cryptography/hazmat/primitives
copying src/cryptography/hazmat/primitives/serialization.py -> build/lib.linux-x86_64-2.7/cryptography/hazmat/primitives
copying src/cryptography/hazmat/primitives/padding.py -> build/lib.linux-x86_64-2.7/cryptography/hazmat/primitives
copying src/cryptography/hazmat/primitives/__init__.py -> build/lib.linux-x86_64-2.7/cryptography/hazmat/primitives
copying src/cryptography/hazmat/primitives/constant_time.py -> build/lib.linux-x86_64-2.7/cryptography/hazmat/primitives
creating build/lib.linux-x86_64-2.7/cryptography/hazmat/backends
copying src/cryptography/hazmat/backends/multibackend.py -> build/lib.linux-x86_64-2.7/cryptography/hazmat/backends
copying src/cryptography/hazmat/backends/__init__.py -> build/lib.linux-x86_64-2.7/cryptography/hazmat/backends
copying src/cryptography/hazmat/backends/interfaces.py -> build/lib.linux-x86_64-2.7/cryptography/hazmat/backends
creating build/lib.linux-x86_64-2.7/cryptography/hazmat/bindings/commoncrypto
copying src/cryptography/hazmat/bindings/commoncrypto/__init__.py -> build/lib.linux-x86_64-2.7/cryptography/hazmat/bindings/commoncrypto
copying src/cryptography/hazmat/bindings/commoncrypto/binding.py -> build/lib.linux-x86_64-2.7/cryptography/hazmat/bindings/commoncrypto
creating build/lib.linux-x86_64-2.7/cryptography/hazmat/bindings/openssl
copying src/cryptography/hazmat/bindings/openssl/__init__.py -> build/lib.linux-x86_64-2.7/cryptography/hazmat/bindings/openssl
copying src/cryptography/hazmat/bindings/openssl/binding.py -> build/lib.linux-x86_64-2.7/cryptography/hazmat/bindings/openssl
copying src/cryptography/hazmat/bindings/openssl/_conditional.py -> build/lib.linux-x86_64-2.7/cryptography/hazmat/bindings/openssl
creating build/lib.linux-x86_64-2.7/cryptography/hazmat/primitives/asymmetric
copying src/cryptography/hazmat/primitives/asymmetric/ec.py -> build/lib.linux-x86_64-2.7/cryptography/hazmat/primitives/asymmetric
copying src/cryptography/hazmat/primitives/asymmetric/utils.py -> build/lib.linux-x86_64-2.7/cryptography/hazmat/primitives/asymmetric
copying src/cryptography/hazmat/primitives/asymmetric/dsa.py -> build/lib.linux-x86_64-2.7/cryptography/hazmat/primitives/asymmetric
copying src/cryptography/hazmat/primitives/asymmetric/padding.py -> build/lib.linux-x86_64-2.7/cryptography/hazmat/primitives/asymmetric
copying src/cryptography/hazmat/primitives/asymmetric/rsa.py -> build/lib.linux-x86_64-2.7/cryptography/hazmat/primitives/asymmetric
copying src/cryptography/hazmat/primitives/asymmetric/__init__.py -> build/lib.linux-x86_64-2.7/cryptography/hazmat/primitives/asymmetric
copying src/cryptography/hazmat/primitives/asymmetric/dh.py -> build/lib.linux-x86_64-2.7/cryptography/hazmat/primitives/asymmetric
creating build/lib.linux-x86_64-2.7/cryptography/hazmat/primitives/kdf
copying src/cryptography/hazmat/primitives/kdf/pbkdf2.py -> build/lib.linux-x86_64-2.7/cryptography/hazmat/primitives/kdf
copying src/cryptography/hazmat/primitives/kdf/kbkdf.py -> build/lib.linux-x86_64-2.7/cryptography/hazmat/primitives/kdf
copying src/cryptography/hazmat/primitives/kdf/hkdf.py -> build/lib.linux-x86_64-2.7/cryptography/hazmat/primitives/kdf
copying src/cryptography/hazmat/primitives/kdf/x963kdf.py -> build/lib.linux-x86_64-2.7/cryptography/hazmat/primitives/kdf
copying src/cryptography/hazmat/primitives/kdf/__init__.py -> build/lib.linux-x86_64-2.7/cryptography/hazmat/primitives/kdf
copying src/cryptography/hazmat/primitives/kdf/concatkdf.py -> build/lib.linux-x86_64-2.7/cryptography/hazmat/primitives/kdf
creating build/lib.linux-x86_64-2.7/cryptography/hazmat/primitives/ciphers
copying src/cryptography/hazmat/primitives/ciphers/algorithms.py -> build/lib.linux-x86_64-2.7/cryptography/hazmat/primitives/ciphers
copying src/cryptography/hazmat/primitives/ciphers/modes.py -> build/lib.linux-x86_64-2.7/cryptography/hazmat/primitives/ciphers
copying src/cryptography/hazmat/primitives/ciphers/__init__.py -> build/lib.linux-x86_64-2.7/cryptography/hazmat/primitives/ciphers
copying src/cryptography/hazmat/primitives/ciphers/base.py -> build/lib.linux-x86_64-2.7/cryptography/hazmat/primitives/ciphers
creating build/lib.linux-x86_64-2.7/cryptography/hazmat/primitives/interfaces
copying src/cryptography/hazmat/primitives/interfaces/__init__.py -> build/lib.linux-x86_64-2.7/cryptography/hazmat/primitives/interfaces
creating build/lib.linux-x86_64-2.7/cryptography/hazmat/primitives/twofactor
copying src/cryptography/hazmat/primitives/twofactor/utils.py -> build/lib.linux-x86_64-2.7/cryptography/hazmat/primitives/twofactor
copying src/cryptography/hazmat/primitives/twofactor/hotp.py -> build/lib.linux-x86_64-2.7/cryptography/hazmat/primitives/twofactor
copying src/cryptography/hazmat/primitives/twofactor/__init__.py -> build/lib.linux-x86_64-2.7/cryptography/hazmat/primitives/twofactor
copying src/cryptography/hazmat/primitives/twofactor/totp.py -> build/lib.linux-x86_64-2.7/cryptography/hazmat/primitives/twofactor
creating build/lib.linux-x86_64-2.7/cryptography/hazmat/backends/commoncrypto
copying src/cryptography/hazmat/backends/commoncrypto/hmac.py -> build/lib.linux-x86_64-2.7/cryptography/hazmat/backends/commoncrypto
copying src/cryptography/hazmat/backends/commoncrypto/hashes.py -> build/lib.linux-x86_64-2.7/cryptography/hazmat/backends/commoncrypto
copying src/cryptography/hazmat/backends/commoncrypto/__init__.py -> build/lib.linux-x86_64-2.7/cryptography/hazmat/backends/commoncrypto
copying src/cryptography/hazmat/backends/commoncrypto/backend.py -> build/lib.linux-x86_64-2.7/cryptography/hazmat/backends/commoncrypto
copying src/cryptography/hazmat/backends/commoncrypto/ciphers.py -> build/lib.linux-x86_64-2.7/cryptography/hazmat/backends/commoncrypto
creating build/lib.linux-x86_64-2.7/cryptography/hazmat/backends/openssl
copying src/cryptography/hazmat/backends/openssl/hmac.py -> build/lib.linux-x86_64-2.7/cryptography/hazmat/backends/openssl
copying src/cryptography/hazmat/backends/openssl/ec.py -> build/lib.linux-x86_64-2.7/cryptography/hazmat/backends/openssl
copying src/cryptography/hazmat/backends/openssl/hashes.py -> build/lib.linux-x86_64-2.7/cryptography/hazmat/backends/openssl
copying src/cryptography/hazmat/backends/openssl/utils.py -> build/lib.linux-x86_64-2.7/cryptography/hazmat/backends/openssl
copying src/cryptography/hazmat/backends/openssl/dsa.py -> build/lib.linux-x86_64-2.7/cryptography/hazmat/backends/openssl
copying src/cryptography/hazmat/backends/openssl/cmac.py -> build/lib.linux-x86_64-2.7/cryptography/hazmat/backends/openssl
copying src/cryptography/hazmat/backends/openssl/x509.py -> build/lib.linux-x86_64-2.7/cryptography/hazmat/backends/openssl
copying src/cryptography/hazmat/backends/openssl/decode_asn1.py -> build/lib.linux-x86_64-2.7/cryptography/hazmat/backends/openssl
copying src/cryptography/hazmat/backends/openssl/rsa.py -> build/lib.linux-x86_64-2.7/cryptography/hazmat/backends/openssl
copying src/cryptography/hazmat/backends/openssl/encode_asn1.py -> build/lib.linux-x86_64-2.7/cryptography/hazmat/backends/openssl
copying src/cryptography/hazmat/backends/openssl/__init__.py -> build/lib.linux-x86_64-2.7/cryptography/hazmat/backends/openssl
copying src/cryptography/hazmat/backends/openssl/backend.py -> build/lib.linux-x86_64-2.7/cryptography/hazmat/backends/openssl
copying src/cryptography/hazmat/backends/openssl/ciphers.py -> build/lib.linux-x86_64-2.7/cryptography/hazmat/backends/openssl
running egg_info
writing requirements to src/cryptography.egg-info/requires.txt
writing src/cryptography.egg-info/PKG-INFO
writing top-level names to src/cryptography.egg-info/top_level.txt
writing dependency_links to src/cryptography.egg-info/dependency_links.txt
writing entry points to src/cryptography.egg-info/entry_points.txt
warning: manifest_maker: standard file '-c' not found
reading manifest file 'src/cryptography.egg-info/SOURCES.txt'
reading manifest template 'MANIFEST.in'
no previously-included directories found matching 'docs/_build'
warning: no previously-included files matching '*' found under directory 'vectors'
writing manifest file 'src/cryptography.egg-info/SOURCES.txt'
running build_ext
generating cffi module 'build/temp.linux-x86_64-2.7/_padding.c'
creating build/temp.linux-x86_64-2.7
generating cffi module 'build/temp.linux-x86_64-2.7/_constant_time.c'
generating cffi module 'build/temp.linux-x86_64-2.7/_openssl.c'
building '_openssl' extension
creating build/temp.linux-x86_64-2.7/build
creating build/temp.linux-x86_64-2.7/build/temp.linux-x86_64-2.7
x86_64-linux-gnu-gcc -pthread -DNDEBUG -g -fwrapv -O2 -Wall -Wstrict-prototypes -fno-strict-aliasing -Wdate-time -D_FORTIFY_SOURCE=2 -g -fstack-protector-strong -Wformat -Werror=format-security -fPIC -I/usr/include/python2.7 -c build/temp.linux-x86_64-2.7/_openssl.c -o build/temp.linux-x86_64-2.7/build/temp.linux-x86_64-2.7/_openssl.o
build/temp.linux-x86_64-2.7/_openssl.c:434:30: fatal error: openssl/opensslv.h: No such file or directory
compilation terminated.
error: command 'x86_64-linux-gnu-gcc' failed with exit status 1
Command "/home/hamadi/portiaenv/bin/python -u -c "import setuptools, tokenize;__file__='/tmp/pip-build-9Ep3g_/cryptography/setup.py';f=getattr(tokenize, 'open', open)(__file__);code=f.read().replace('\r\n', '\n');f.close();exec(compile(code, __file__, 'exec'))" install --record /tmp/pip-PhGYOx-record/install-record.txt --single-version-externally-managed --compile --install-headers /home/hamadi/portiaenv/include/site/python2.7/cryptography" failed with error code 1 in /tmp/pip-build-9Ep3g_/cryptography/
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I have problems when installing ubuntu Portia to 16:04
Command "/home/hamadi/portiaenv/bin/python -u -c "import setuptools, tokenize;__file__='/tmp/pip-build-9Ep3g_/cryptography/setup.py';f=getattr(tokenize, 'open', open)(__file__);code=f.read().replace('\r\n', '\n');f.close();exec(compile(code, __file__, 'exec'))" install --record /tmp/pip-PhGYOx-record/install-record.txt --single-version-externally-managed --compile --install-headers /home/hamadi/portiaenv/include/site/python2.7/cryptography" failed with error code 1 in /tmp/pip-build-9Ep3g_/cryptography/
My installation steps are in accordance with the instructions http://portia.readthedocs.io/en/latest/installation.html
A:
You are missing the dependencies for cryptography, which is a dependency of portia. Follow the installation instructions for cryptography to install the deps you need and then retry.
| 2023-08-03T01:26:59.872264 | https://example.com/article/8748 |
Punta Cana
Punta Cana
from 65.00
Punta Cana is a beautiful area on the coast of The Dominican Republic. There were back to back mornings with a fabulous sunrise coming up over the water and behind me a rainbow. I love the peace of sunrises. While most people are just waking up, sunrise is there to greet me with a warm hello! | 2024-05-14T01:26:59.872264 | https://example.com/article/7941 |
Q:
How to read keyboard-input?
I would like to read data from the keyboard in python
I try this:
nb = input('Choose a number')
print ('Number%s \n' % (nb))
But it doesn't work, neither with eclipse nor in the terminal, it's always stop of the question. I can type a number but after nothing happen.
Do you know why?
A:
try
raw_input('Enter your input:') # If you use Python 2
input('Enter your input:') # If you use Python 3
and if you want to have a numeric value
just convert it:
try:
mode=int(raw_input('Input:'))
except ValueError:
print "Not a number"
A:
It seems that you are mixing different Pythons here (Python 2.x vs. Python 3.x)...
This is basically correct:
nb = input('Choose a number: ')
The problem is that it is only supported in Python 3. As @sharpner answered, for older versions of Python (2.x), you have to use the function raw_input:
nb = raw_input('Choose a number: ')
If you want to convert that to a number, then you should try:
number = int(nb)
... though you need to take into account that this can raise an exception:
try:
number = int(nb)
except ValueError:
print("Invalid number")
And if you want to print the number using formatting, in Python 3 str.format() is recommended:
print("Number: {0}\n".format(number))
Instead of:
print('Number %s \n' % (nb))
But both options (str.format() and %) do work in both Python 2.7 and Python 3.
A:
Non-blocking, multi-threaded example:
As blocking on keyboard input (since the input() function blocks) is frequently not what we want to do (we'd frequently like to keep doing other stuff), here's a very-stripped-down multi-threaded example to demonstrate how to keep running your main application while still reading in keyboard inputs whenever they arrive.
This works by creating one thread to run in the background, continually calling input() and then passing any data it receives to a queue.
In this way, your main thread is left to do anything it wants, receiving the keyboard input data from the first thread whenever there is something in the queue.
1. Bare Python 3 code example (no comments):
import threading
import queue
import time
def read_kbd_input(inputQueue):
print('Ready for keyboard input:')
while (True):
input_str = input()
inputQueue.put(input_str)
def main():
EXIT_COMMAND = "exit"
inputQueue = queue.Queue()
inputThread = threading.Thread(target=read_kbd_input, args=(inputQueue,), daemon=True)
inputThread.start()
while (True):
if (inputQueue.qsize() > 0):
input_str = inputQueue.get()
print("input_str = {}".format(input_str))
if (input_str == EXIT_COMMAND):
print("Exiting serial terminal.")
break
# Insert your code here to do whatever you want with the input_str.
# The rest of your program goes here.
time.sleep(0.01)
print("End.")
if (__name__ == '__main__'):
main()
2. Same Python 3 code as above, but with extensive explanatory comments:
"""
read_keyboard_input.py
Gabriel Staples
www.ElectricRCAircraftGuy.com
14 Nov. 2018
References:
- https://pyserial.readthedocs.io/en/latest/pyserial_api.html
- *****https://www.tutorialspoint.com/python/python_multithreading.htm
- *****https://en.wikibooks.org/wiki/Python_Programming/Threading
- https://stackoverflow.com/questions/1607612/python-how-do-i-make-a-subclass-from-a-superclass
- https://docs.python.org/3/library/queue.html
- https://docs.python.org/3.7/library/threading.html
To install PySerial: `sudo python3 -m pip install pyserial`
To run this program: `python3 this_filename.py`
"""
import threading
import queue
import time
def read_kbd_input(inputQueue):
print('Ready for keyboard input:')
while (True):
# Receive keyboard input from user.
input_str = input()
# Enqueue this input string.
# Note: Lock not required here since we are only calling a single Queue method, not a sequence of them
# which would otherwise need to be treated as one atomic operation.
inputQueue.put(input_str)
def main():
EXIT_COMMAND = "exit" # Command to exit this program
# The following threading lock is required only if you need to enforce atomic access to a chunk of multiple queue
# method calls in a row. Use this if you have such a need, as follows:
# 1. Pass queueLock as an input parameter to whichever function requires it.
# 2. Call queueLock.acquire() to obtain the lock.
# 3. Do your series of queue calls which need to be treated as one big atomic operation, such as calling
# inputQueue.qsize(), followed by inputQueue.put(), for example.
# 4. Call queueLock.release() to release the lock.
# queueLock = threading.Lock()
#Keyboard input queue to pass data from the thread reading the keyboard inputs to the main thread.
inputQueue = queue.Queue()
# Create & start a thread to read keyboard inputs.
# Set daemon to True to auto-kill this thread when all other non-daemonic threads are exited. This is desired since
# this thread has no cleanup to do, which would otherwise require a more graceful approach to clean up then exit.
inputThread = threading.Thread(target=read_kbd_input, args=(inputQueue,), daemon=True)
inputThread.start()
# Main loop
while (True):
# Read keyboard inputs
# Note: if this queue were being read in multiple places we would need to use the queueLock above to ensure
# multi-method-call atomic access. Since this is the only place we are removing from the queue, however, in this
# example program, no locks are required.
if (inputQueue.qsize() > 0):
input_str = inputQueue.get()
print("input_str = {}".format(input_str))
if (input_str == EXIT_COMMAND):
print("Exiting serial terminal.")
break # exit the while loop
# Insert your code here to do whatever you want with the input_str.
# The rest of your program goes here.
# Sleep for a short time to prevent this thread from sucking up all of your CPU resources on your PC.
time.sleep(0.01)
print("End.")
# If you run this Python file directly (ex: via `python3 this_filename.py`), do the following:
if (__name__ == '__main__'):
main()
Sample output:
$ python3 read_keyboard_input.py
Ready for keyboard input:
hey
input_str = hey
hello
input_str = hello
7000
input_str = 7000
exit
input_str = exit
Exiting serial terminal.
End.
References:
https://pyserial.readthedocs.io/en/latest/pyserial_api.html
*****https://www.tutorialspoint.com/python/python_multithreading.htm
*****https://en.wikibooks.org/wiki/Python_Programming/Threading
Python: How do I make a subclass from a superclass?
https://docs.python.org/3/library/queue.html
https://docs.python.org/3.7/library/threading.html
Related/Cross-Linked:
PySerial non-blocking read loop
| 2024-04-26T01:26:59.872264 | https://example.com/article/5279 |
1. Introduction {#sec1-ijms-19-03860}
===============
Mature eukaryotic proteins consist not only of structural domains (SDs), but also of intrinsically disordered regions (IDRs), i.e., regions that by themselves do not fold into unique three-dimensional structures \[[@B1-ijms-19-03860]\]. Although some IDRs interact with proteins or other macromolecules, they are generally under less constraint than SDs and thus have higher evolution rates \[[@B2-ijms-19-03860]\]. A positive correlation between fractional IDR contents of proteins and evolution rates is thus expected.
Proteins with more protein-to-protein interactions (PPIs) tend to be more evolutionarily constrained and have lower evolution rates \[[@B3-ijms-19-03860],[@B4-ijms-19-03860]\]. Highly expressed proteins are also more constrained and evolve slowly \[[@B4-ijms-19-03860],[@B5-ijms-19-03860],[@B6-ijms-19-03860]\]. These two factors partially account for the evolution rate of proteins.
Eukaryotic proteins have specific subcellular localizations in general, with different average fractional IDR contents in different cellular localizations \[[@B7-ijms-19-03860]\]. For instance, IDR contents are generally high in nuclear proteins \[[@B7-ijms-19-03860],[@B8-ijms-19-03860]\], while they tend to be low in mitochondrial proteins \[[@B9-ijms-19-03860],[@B10-ijms-19-03860]\]. It is plausible that different fractional IDR contents in different subcellular localizations result in varied evolution rates.
Interestingly, extracellular proteins (synonymously called secreted proteins) in mammalian species were often found to evolve faster than intracellular proteins \[[@B11-ijms-19-03860],[@B12-ijms-19-03860]\]. This finding is partly explainable by rapid evolution of immune-related extracellular proteins as many of the coding genes are subject to positive selection \[[@B13-ijms-19-03860],[@B14-ijms-19-03860]\]. That is, the evolution rate, ω, defined by the nonsynonymous to synonymous substitution rate ratio, exceeds unity at sites under positive selection and the existence of many such sites result in high evolution rates of many immune-related genes. For instance, antimicrobial peptides, α- and β-defensins and cathelicidins, are reportedly subject to positive selection and evolve rapidly in mammals \[[@B15-ijms-19-03860],[@B16-ijms-19-03860],[@B17-ijms-19-03860]\]. We consider it worthwhile to carry out research on evolutionary characteristics of immune-related secreted proteins, as they are involved in host defences \[[@B18-ijms-19-03860]\], pathogen--host interactions \[[@B19-ijms-19-03860],[@B20-ijms-19-03860]\], production of antibodies \[[@B21-ijms-19-03860]\], colony-stimulating factors \[[@B22-ijms-19-03860]\], haematopoiesis \[[@B23-ijms-19-03860]\], and triggering proteolytic cascades \[[@B24-ijms-19-03860],[@B25-ijms-19-03860]\], as well as enzyme replacement therapies \[[@B26-ijms-19-03860]\]. The generally high evolution of immune-related proteins evinces their importance in evolution of mammalian species \[[@B27-ijms-19-03860]\]. Further research may reveal how immune-related proteins function and may lead to pharmaceutical applications.
However, the difference in evolution rate with intracellular proteins remained significant even if analyses were limited to non-immune-related extracellular proteins. The generally low expression levels in secreted proteins partially explain the rapid evolution. Whether the substitution frequency in IDRs or SDs or both contributes to the increased evolution rate of extracellular proteins, however, has not been explored.
We examined the correlation of fractional IDR content and evolution rate and found it positive. We then analyzed the evolution rates of SDs and IDRs of proteins in different localizations. In most localizations, IDRs were found to evolve faster than SDs, as expected. Immune-related secreted proteins in mammals, however, exhibited extremely high evolution rates in SDs that approach those in IDRs. This surprising finding indicates that positive selection that is said to function on a number of immune-related genes operates strongly both on IDRs and SDs of the coded proteins.
2. Results and Discussion {#sec2-ijms-19-03860}
=========================
2.1. Classification of Eukaryotic Proteins by Subcellular Localizations {#sec2dot1-ijms-19-03860}
-----------------------------------------------------------------------
For accurate analyses of evolution rates in different subcellular localizations, reliable localization annotations of most proteins are necessary. At present, only four species satisfy this criterion in UniProt: *Homo sapiens*, *Mus musculus* (mouse), *Arabidopsis thaliana* (thale cress), and *Saccharomyces cerevisiae* (budding yeast). We thus selected the human, mouse, thale cress, and budding yeast proteins with orthologs and classified the selected proteins by subcellular localization ([Table 1](#ijms-19-03860-t001){ref-type="table"}). Proteins that are localized to both the nucleus and the cytosol were specifically grouped (abbreviated as NC), as the group reportedly contains many proteins with multiple PPIs \[[@B28-ijms-19-03860]\]. We combined proteins residing in the endoplasmic reticulum and the Golgi apparatus (termed EG), since many proteins cycle between the two organells. Secreted proteins were divided into immune-related (SI) and non-immune-related (SN), because immune-related proteins generally evolve rapidly \[[@B11-ijms-19-03860]\]. Thale cress had a limited number of immune-related proteins, while unsurprisingly budding yeast had none. Multiply localized proteins except for the aforementioned NC proteins were classified as one group (ML). Note that many proteins with orthologs were not classifiable due to the unavailability of pertinent information.
2.2. Evolution Rates and Other Properties of Proteins in Different Subcellular Localizations {#sec2dot2-ijms-19-03860}
--------------------------------------------------------------------------------------------
For each pair of orthologs, we determined the evolution rate, ω, defined by the ratio of nonsynonymous to synonymous substitution rate, i.e., dN/dS. The median ω at each localization is shown ([Figure 1](#ijms-19-03860-f001){ref-type="fig"} and [Figure 2](#ijms-19-03860-f002){ref-type="fig"}). Note that for this and other data presented in the figure, different scales were used in different species. As the number of immune-related proteins (SI) in *A. thaliana* is small, no corresponding data were plotted in this species. Proteins of the four species showed similar patterns. For instance proteins in the cytosol (CY) and those that reside both in the nucleus and the cytosol (NC) had the median evolution rates lower than the overall median in all four species. In general the median evolution rates in intracellular proteins (NU, NC, CY, MT, and EG; shown in blue) were lower than those of secreted proteins (SN and SI; shown in red). Among the secreted proteins, immune-related proteins (SI) exhibited particularly high evolution rates, in agreement with the literature \[[@B13-ijms-19-03860],[@B14-ijms-19-03860]\].
The fractional IDR content of each protein was predicted by DISOPRED \[[@B29-ijms-19-03860]\], DICHOT \[[@B30-ijms-19-03860]\], and POODLE-L \[[@B31-ijms-19-03860]\] and the median in each localization was calculated ([Figure 1](#ijms-19-03860-f001){ref-type="fig"} and [Figure 2](#ijms-19-03860-f002){ref-type="fig"}). Although the medians of most localizations ([Figure 1](#ijms-19-03860-f001){ref-type="fig"} and [Figure 2](#ijms-19-03860-f002){ref-type="fig"}) were nearly always the lowest by DISOPRED, higher by DICHOT, and the highest by POODLE, we note that the overall averages by the three methods generally do not differ much. For instance, the fractions of IDRs in human proteins by DISOPRED, DICHOT, POODLE are 30.2%, 26.4%, and 30.1%, respectively. The differences in the medians are thus mostly attributable to differences in the distributions of fractional IDRs. Nevertheless the corresponding medians by the three prediction methods showed similar patterns. For instance, by all three methods in the four species, we got high fractional IDR contents in the nuclear proteins (NU) and low values in the mitochondrial proteins (MT), consistent with previous reports \[[@B7-ijms-19-03860],[@B8-ijms-19-03860],[@B9-ijms-19-03860],[@B10-ijms-19-03860]\]. Intriguingly, the secreted non-immune proteins (SN) in budding yeast were revealed to have a high median IDR content, unlike the counterparts of the three multicellular eukaryotes. The difference may reflect the difference between unicellular and multicellular organisms. This issue needs to be addressed later with analyses of more eukaryotes.
We also calculated and graphed the median numbers of PPIs of proteins in the localizations ([Figure 1](#ijms-19-03860-f001){ref-type="fig"} and [Figure 2](#ijms-19-03860-f002){ref-type="fig"}). PPIs have been less studied in mouse and thale cress proteins than in human and budding yeast counterparts, as evidenced by the reduced numbers of PPIs in mouse and thale cress ([Figure 1](#ijms-19-03860-f001){ref-type="fig"}B and [Figure 2](#ijms-19-03860-f002){ref-type="fig"}A). The mouse and thale cress PPI data are therefore less reliable as those of the other two species. As reported \[[@B28-ijms-19-03860]\], multiply localized proteins (NC and ML) generally showed more interactions with other proteins. Immune-related secreted proteins (SI), however, had fewer interacting partners on average.
Additionally, the median expression level in ppm of the proteins at each localization was determined and graphed as logarithms to the base of ten ([Figure 1](#ijms-19-03860-f001){ref-type="fig"} and [Figure 2](#ijms-19-03860-f002){ref-type="fig"}). Yeast proteins were generally expressed much more than mammalian proteins. The expression levels of the human immune-related proteins (SI) were generally high, but those of the mouse counterparts were indistinguishable from the average.
2.3. Correlation of Evolution Rates with Protein Properties {#sec2dot3-ijms-19-03860}
-----------------------------------------------------------
We computed Spearman's correlation coefficients (Rhos) of number of PPIs with evolution rate (ω) and found them to be weakly negative but significantly different from zero (all at *p* \< 0.01) ([Table 2](#ijms-19-03860-t002){ref-type="table"}). The negative correlation is consistent with previous results \[[@B3-ijms-19-03860],[@B4-ijms-19-03860]\]. As the number of PPIs was generally low in extracellular proteins (SN and SI, [Figure 1](#ijms-19-03860-f001){ref-type="fig"} and [Figure 2](#ijms-19-03860-f002){ref-type="fig"}), the negative correlation partially explains their high evolution rates.
We also found small but significant (all at *p* \< 1 × 10^−113^) negative correlations between expression level and **ω** ([Table 2](#ijms-19-03860-t002){ref-type="table"}), corroborating previous findings \[[@B5-ijms-19-03860],[@B6-ijms-19-03860]\]. The negative correlation was stronger in budding yeast. Since the expression levels of non-immune-related secreted proteins (SN) were not high ([Figure 1](#ijms-19-03860-f001){ref-type="fig"} and [Figure 2](#ijms-19-03860-f002){ref-type="fig"}), the negative correlation at least in part explains the high evolution rates of these proteins. By contrast the expression levels of immune-related secreted proteins (SI) were not significantly low ([Figure 1](#ijms-19-03860-f001){ref-type="fig"}) and do not contribute to the extremely high evolution rates.
As IDRs have a propensity to evolve faster than SDs, the more IDRs a protein has, the faster it is expected to evolve. To test this possibility, correlation coefficients of %IDR with **ω** were calculated. Fractional IDR content was positively correlated with evolution rate in all the four species ([Table 2](#ijms-19-03860-t002){ref-type="table"}). Although the correlation coefficients were generally small, they all significantly differed from zero (at *p* \< 1 × 10^−4^). As the median fractional IDR contents in immune-related secreted proteins (SI) were lower than average, this factor does not make positive contribution to the evolution rates.
2.4. Evolution Rates in SDs and IDRs in Different Subcellular Localizations {#sec2dot4-ijms-19-03860}
---------------------------------------------------------------------------
In order to see whether IDRs or SDs in immune-related proteins mostly account for the high evolution rates, we calculated the evolution rates in IDRs and SDs separately and compared the two. The median evolution rate in IDRs in all proteins was significantly higher than that in SDs, irrespective of species ([Figure 3](#ijms-19-03860-f003){ref-type="fig"} and [Figure S1](#app1-ijms-19-03860){ref-type="app"}). We detected the same disparity at most localizations.
Upon closer examination of the mammalian rates, we noticed that the IDR/SD evolution rate ratio tended to be higher in intracellular localizations (NU, NC, CY, MT, and EG) than in extracellular ones (SN and SI). In the plant *A. thaliana* the inside--outside difference in evolution rate was detectable but was less pronounced ([Figure S1](#app1-ijms-19-03860){ref-type="app"}A). In contrast, budding yeast failed to show this tendency ([Figure S1](#app1-ijms-19-03860){ref-type="app"}B). In immune-relate secreted proteins (SI), the rates in IDRs and SDs were both higher than average, with the difference between them statistically insignificant in a majority of cases ([Figure 3](#ijms-19-03860-f003){ref-type="fig"}). SDs apparently evolve quite rapidly in immune-related proteins to approach the rates of IDRs to give rise to the anomalously high evolution rates. So far as we are aware, the phenomenon of the evolution rate in SDs that comes close that in IDRs in immune-related proteins is the first to be reported. The non-immune related extracellular proteins (SN) also tended to have higher than average evolution rate in SDs in *H. sapiens* and *M. musculus*, and *A. thaliana*, although the difference from the average was more conspicuous in the two mammals ([Figure 3](#ijms-19-03860-f003){ref-type="fig"}) than in the plant species ([Figure S1](#app1-ijms-19-03860){ref-type="app"}A). In contrast SDs in non-immune related extracellular proteins (SN) did not show an above-average evolution rate in *S. cerevisiaie* ([Figure S1](#app1-ijms-19-03860){ref-type="app"}B). In mammalian mitochondrial (MT) and plasma membrane (PM) proteins, the evolution rates of SDs and IDRs were close to each other ([Figure 3](#ijms-19-03860-f003){ref-type="fig"}), although the former was significantly higher than the latter in all cases. By contrast the counterparts in the two non-mammalian species failed to show the tendency ([Figure S1](#app1-ijms-19-03860){ref-type="app"}). We need to investigate other species before attaching any significance to this possibly mammalian-specific phenomenon.
We recognize the need to analyze more animal species to check the generality of our finding on immune-related extracellular proteins. For accurate analyses by the same methodology, however, two closely related and entirely sequenced species must be available and at least one of them must have a majority of proteins annotated by UniProt to provide reliable subcellular localizations. Unfortunately no animal species other than *H. sapiens* and *M. musculus* currently meet the latter criterion. Since 3463 (\~22% of the total) *Drosophila melanogaster* proteins have been annotated, however, we carried out preliminary analyses of this fly. Thirty-eight annotated immune-related extracellular proteins were identified in 13,957 orthologs. The results showed that the evolution rates in IDRs and SDs were both high in immune-related proteins but the former was much higher than the latter. The ratio of the median evolution rate in IDRs to that in SDs was 2.37, 1.60, and 2.99 by DISOPRED, DICHOT, and POODLE, respectively. As the corresponding ratios of all *Drosophila* proteins were 2.10, 2.45, and 1.79, the ratio was not necessarily diminished in immune-related proteins in fruit fly. Thus, the preliminary results indicate that the phenomenon of rapid evolution in both SD and IDRs in immune-related secreted proteins is possibly limited to vertebrates.
In the cytosolic proteins (CY) of budding yeast, the median evolution rate in IDRs was only a little higher than that in SDs ([Figure S1](#app1-ijms-19-03860){ref-type="app"}B). As noted before, budding yeast proteins generally interact with much more proteins than human proteins and did not exhibit intracellular-extracellular disparity in the IDR to SD evolution ratio.
2.5. Examles of Proteins with Nonsynonymous and Synonymous Substitutions {#sec2dot5-ijms-19-03860}
------------------------------------------------------------------------
To give specific examples, we diagramed some human and mouse proteins with locations of nonsynonymous and synonymous substitutions ([Figure 4](#ijms-19-03860-f004){ref-type="fig"}). As we selected the proteins as they exhibit close-to-median ratios of nonsynonymous to synonymous substitution rates in SDs and IDRs, the frequencies of nonsynonymous to synonymous substitutions do not necessarily show median values. Although the three prediction methods gave different results, the major disparities were found in the boundaries of IDRs and did not affect main results. In immune-related secreted proteins ([Figure 4](#ijms-19-03860-f004){ref-type="fig"}A--D), nonsynonymous mutations (red bars) were almost as frequent as synonymous ones (black bars) both in IDRs (pink rectangles) and SDs (gray regions). In comparison, in proteins of other subcellular localizations, nonsynonymous substitutions occurred much less frequently than synonymous substitutions in SDs, while the difference was less pronounced in IDRs ([Figure 4](#ijms-19-03860-f004){ref-type="fig"}E--H).
2.6. Significance and Remaining Issues {#sec2dot6-ijms-19-03860}
--------------------------------------
The generally much lower frequency of nonsynonymous substitutions than synonymous substitutions in SDs reflects the fact that nonsynonymous changes very often destabilize the structures. By contrast, the difference between nonsynonymous and synonymous substitution rates is diminished in IDRs as nonsynonymous changes are frequently accommodated in IDRs. Consequently the ratio of nonsynonymous to synonymous substitution rate (ω) is expected to be much smaller in SDs than in IDRs. Although the actual results obtained in this research were mostly consistent with this expectation, those of immune-related secreted proteins of the two mammalian species were not; ω in SDs approaches that in IDRs.
As ω is larger than 1 at positively selected sites, the existence of numerous such sites in a region increases the average ω. Since many sites in immune-related secreted proteins were reported to be under positive selection \[[@B13-ijms-19-03860],[@B14-ijms-19-03860],[@B15-ijms-19-03860],[@B16-ijms-19-03860],[@B17-ijms-19-03860]\], the heightened ω in SDs of such proteins indicates that many positively selected sites fall in SDs. The observation that IDRs of immune-related proteins exhibit higher ω than those of other proteins also implies that IDRs contain positively selected sites, too. The classification of positively selected sites in immune-related proteins into SDs and IDRs will probably lead to a better understanding of mechanisms of immunity. It is plausible that many nonsynonymous changes occur at the surface of SDs that interacts with other proteins.
It is also of interest to investigate known genes under positive selection that are associated with gamete recognition \[[@B32-ijms-19-03860],[@B33-ijms-19-03860]\] and male reproduction \[[@B34-ijms-19-03860],[@B35-ijms-19-03860]\] to find if SDs as well as IDRs of the encoded proteins evolve rapidly. We note that extracellular domains receive a number of posttranslational modifications such as phosphorylations, glycosylation, and lipidation. Investigation of evolution rates at posttranslational modification sites of immune-related proteins is another prospective area.
3. Materials and Methods {#sec3-ijms-19-03860}
========================
The nucleotide sequences of *H. sapience*, *M. musculus,* and *Rattus norvegicus* genes were downloaded from Ensembl (Release 91) \[[@B36-ijms-19-03860]\]. The nucleotide sequences of *A. thaliana* (TAIR10), *Arabidopsis lyrata*, *Drosophila melanogaster* (BDGP6) genes were obtained from Ensembl, too. Ensembl also provided the orthologous relationships between *H. sapience* and *M. musculus* as well as those of *M. musculus* and *R. norvegicus*. The sequences of *S. cerevisiae* and *Saccharomyces paradoxus* were obtained from the Saccharomyces Genome Database \[[@B37-ijms-19-03860]\], while those of *Drosophila pseudoobscura* genes were downloaded from FlyBase \[[@B38-ijms-19-03860]\]. The orthologs of the two *Arabisopsis* species, the two yeast species, and the two *Drosophila* species were selected by bidirectional best hit analysis. The proteins were classified by subcellular localizations based on the Gene-Ontology (GO) annotations in UniProt (Release 2017_05) \[[@B39-ijms-19-03860]\]. Specifically, the following GO IDs were used for subcellular classifications: nucleus: GO:0005634; cytoplasm: GO:0005829; mitochondria: GO:0005739; endoplasmic reticulum/Golgi apparatus: GO:0005783, GO:0005794, and GO:0005793; plasma membrane: GO:0005886; secreted: GO:0005576 and GO:0005615; immune-related: GO:0002376.
From the coding sequences, the signal peptides were removed based on UniProt annotations because they are unclassifiable as SDs or IDRs due to their absence in mature proteins. The remaining amino acid sequences of orthologs were aligned by MAFFT \[[@B40-ijms-19-03860]\] and the corresponding nucleotide sequences were aligned according to the MAFFT results. dn/ds values were then computed using the codeml program (model M0) in PAML (version 4.9d) \[[@B41-ijms-19-03860]\]. Statistical differences between two quantities were tested by Mann-Whitney's *U*-test, while statistical significance of correlations was evaluated by Spearman's rank correlation by means of in-house programs.
Number of PPIs and expression levels were taken from the BioGRID (version 3.4.158) \[[@B42-ijms-19-03860]\] and the PaxDb (version 4.1) \[[@B43-ijms-19-03860]\] databases, respectively. BioGRID is a curated database of interactions including protein-protein interactions obtained by two-hybrid studies, affinity purification coupled to mass spectrometry, and other methods, while PaxDB contains whole genome protein abundance information obtained by integrating numerous datasets using scores and ranks. Each protein was divided into SDs and IDRs by three methods: DISOPRED3 \[[@B29-ijms-19-03860]\], DICHOT \[[@B30-ijms-19-03860]\] and POODLE-L \[[@B31-ijms-19-03860]\]. Briefly, DISOPRED3 assigns IDRs based on sequence profiles and other sequence-derived features, DICHOT classifies proteins into SDs and IDRs using sequence characteristics, alignments to existing protein structures, and sequence divergence, while POODLE-L is a prediction method for long IDRs that makes use of support-vector machine with 10 kinds of simple physico-chemical properties of amino acids. Based on the overall MAFFT alignments, the alignments of the corresponding sections were made. The evolution rate of each section was then determined as above.
4. Conclusions {#sec4-ijms-19-03860}
==============
In human and mouse, the SDs of immune-related proteins evolve at a high rate which comes close to that of the IDRs. This observation indicates that positive selection operates on both SDs and IDRs of the encoded proteins in many immune-related genes. Comparatively high evolution in SDs is also observed in non-immune-related secreted proteins in human and mouse, and to a lesser extent in thale cress, but not in budding yeast. Thus accelerated evolution in SDs as well as in IDRs contributes to rapid evolution of extracellular proteins in mammals.
The following are available online at <http://www.mdpi.com/1422-0067/19/12/3860/s1>.
######
Click here for additional data file.
Conceptualization, K.H.; Methodology, K.H.; Software, H.A., T.N., S.F.; Validation, K.H., H.A., T.N., S.F.; Formal Analysis, K.H.; Investigation, K.H., H.A.; Resources, K.H.; Data Curation, K.H.; Writing-Original Draft Preparation, K.H.; Writing-Review & Editing, K.H.; Visualization, K.H.; Supervision, K.H.; Project Administration, K.H.; Funding Acquisition, K.H.
The authors declare no conflict of interest.
SD
Structural domain
IDR
Intrinsically disordered region
PPI
Protein-to-protein interaction
NU
Nucleus
NC
Nucleus and cytosol
CY
Cytosol
MT
Mitochondria
EG
Endoplasmic reticulum or Golgi apparatus
PM
Plasma membrane
SN
Secreted, non-immune-related
SI
Secreted, immune-related
ML
Multiple localizations except NC
dN
Nonsynonymous substitution rate
dS
Synonymous substitution rate
GO
Gene Ontology
{ref-type="table"}.](ijms-19-03860-g001){#ijms-19-03860-f001}
{ref-type="fig"}.](ijms-19-03860-g002){#ijms-19-03860-f002}
{ref-type="table"} are used.](ijms-19-03860-g003){#ijms-19-03860-f003}
{#ijms-19-03860-f004}
ijms-19-03860-t001_Table 1
######
Number of proteins in each subcellular localization.
Species All NU NC CY MT EG PM SN SI ML
----------------- -------- ------ ----- ----- ----- ----- ------ ----- ----- ------
*H. sapiens* 10,348 1639 632 455 377 400 1116 584 139 3023
*M. musculus* 10,068 1719 546 224 426 514 998 796 125 2787
*A. thaliana* 8910 1032 163 331 356 348 534 431 6 594
*S. cerevisiae* 5304 1532 232 241 639 458 281 69 0 416
NU: Nucleus; NC: Nucleus and cytosol; CY: Cytosol; MT: Mitochondria; EG: Endoplasmic reticulum or Golgi apparatus; PM: Plasma membrane; SN: Secreted, non-immune-related; SI: Secreted, immune-related; ML: Multiple localizations except NC (ML).
ijms-19-03860-t002_Table 2
######
Correlations between three properties and evolution rate **ω**.
Correlation with *H. sapiens* *M. musculus* *A. thaliana* *S. cerevisiae*
------------------------- -------------- --------------- --------------- -----------------
\#PPI with ω −0.293 −0.194 −0.054 −0.195
Expression level with ω −0.264 −0.231 −0.337 −0.459
%IDR (DISOPRED) with ω 0.093 0.094 0.168 0.264
%IDR (DICHOT) with ω 0.113 0.146 0.052 0.303
%IDR (POODLE) with ω 0.096 0.097 0.113 0.179
Spearman's correlation coefficient (Rho) of each pair is shown.
| 2024-01-07T01:26:59.872264 | https://example.com/article/8784 |
Development of a model of the premotor potential.
This study explored the sensory nature of the small negative premotor potential (PMP) that is often seen preceding the compound muscle action potential. We developed a model of the PMP, using the ulnar and superficial radial sensory (SRS) nerves. Standard conduction studies of the deep ulnar motor nerve recording over the first dorsal interosseous manus (FDIM) and of the SRS nerve recording over the same site were done separately, then simultaneously, on 20 normal hands. In all subjects, there was no FDIM PMP, but with simultaneous stimulation of both nerves, there was a potential in all subjects that appeared similar to their median thenar and ulnar hypothenar PMPs. Reference data for the median thenar, ulnar hypothenar, and model PMP were generated. Findings from this study are discussed and appear to support the concept of the PMP being either a sensory potential or a junctional potential. | 2024-02-18T01:26:59.872264 | https://example.com/article/2544 |
Slow braised oxtail recipe for six hungry people
A few years ago I was in Fred Fitzpatrick’s butcher’s shop and spotted a tray of oxtail. My mum was coming for the weekend and somewhere in the vague backwaters of my mind I connected her with oxtail. So I bought the oxtail and rushed home to ring her and announce that we were cooking something very special for the weekend.
She arrived in a fever of excitement. I couldn’t contain the good news until the meal.
“We’ve made you a wonderful oxtail dish.”
When I saw her back straighten and a certain stiffening of the neck, I realised that the connection was clearly negative.
“Oxtail?”
She glanced at our astonished faces and added bravely
“Never mind darling, I am sure I’ll love it.”
And she did.
We used as our starting point the Braised Oxtail recipe from Gary Rhodes New British Classics. We have experimented and played with the recipe endlessly and now I feel I can genuinely publish it as my own. The key to the success of our dish is the slow cooking. We bought an expensive marmite (a large casserole with lid) in a sale a couple of years ago. This giant saucepan is a boon. It is happy to sit in a slow oven for eight hours or on the hob with a trickle heat, without loosing too much moisture. If you are going to try our overnight cooking method, give your casserole a dummy run when you are at home during the day. Then you can check how your own casserole behaves (about 20% of liquid evaporates from our marmite over 9 hours) before popping it in a slow oven for an overnight cook.
1 tsp of balsamic vinegar (added at the beginning always gives a gorgeous depth to a slow cooked dish)
1 tsp of Lea and Perrins
2 tblsps of mushroom ketchup
At least 2 pints of good strong home made brown stock to cover so everything is just floating rather than just covered (Or 2 pints of stock made with 2 beef stock cube and a tsp of Marigold stock powder)
5 small stalks of fresh thyme
Method:
Pour the oil into a large saucepan and fry the tails until brown all over and reserve them in a warm space.
Add the onions, carrots, leeks and garlic to the pot and allow them to soak up the juices as the soften for a few minutws.
Pop in the tails and stir make sure that they are floating in the stock. Bring everything gentle to simmering point and put some foil under the lid of your casserole to ensure a tight fit. Pop the casserole into a slow oven 110c (90c fan), bottom shelf for 8 – 9 hours.
In the morning drain off the liquid and remove the fat (I put it in the fridge to let the fat harden). Then liquidise the vegetables and stock – this will make a thick sauce. Remove the meat from the tails and mix into the sauce. Serve with carrots and a sprinkle of parsley and either mashed potatoes or dumplings. | 2024-06-24T01:26:59.872264 | https://example.com/article/3054 |
{
"cells": [
{
"cell_type": "markdown",
"metadata": {},
"source": [
"# 2.Add Two Numbers\n",
"\n",
"### 难度：Medium\n",
"\n",
"## 刷题内容：\n",
"\n",
"> 原题链接：\n",
"\n",
" - 中文：https://leetcode-cn.com/problems/add-two-numbers\n",
" - 英文：https://leetcode.com/problems/add-two-numbers/\n",
"\n",
"> 内容描述：\n",
"\n",
"给定两个非空链表来表示两个非负整数。位数按照逆序方式存储，它们的每个节点只存储单个数字。将两数相加返回一个新的链表。\n",
"\n",
"你可以假设除了数字 0 之外，这两个数字都不会以零开头。\n",
"\n",
"示例：\n",
"```\n",
"输入：(2 -> 4 -> 3) + (5 -> 6 -> 4)\n",
"输出：7 -> 0 -> 8\n",
"原因：342 + 465 = 807\n",
"```\n",
"\n",
"## 解法方案\n",
"\n",
"由于两数相加可能会出现进位，所以加法我们谁都会算，但是要着重注意的一点是，要考虑上一位的进位，并且传递给下一位计算时的进位。\n",
"\n",
"> 思路 1\n",
"\n",
"我们先构建一个空的头结点不动，然后尾结点从头结点开始向后不断生成新的结点。遍历两个链表的公共部分，每次相加相应位数字和进位，分配到结果的链表中。公共部分遍历完后再确定长的链表剩余的部分，同样的方式遍历完。\n",
"\n",
" - 需要注意的是遍历时每次都要更新进位，不断计算和时有没有发生进位，以防止之前数据的污染。\n",
" - 对于 python 来说，需要新的变量做游标来遍历两个链表，不能直接用形参，否则我们会修改原链表。\n",
" - 注意最后可能的进位。"
]
},
{
"cell_type": "code",
"execution_count": 1,
"metadata": {},
"outputs": [
{
"name": "stdout",
"output_type": "stream",
"text": [
"7\n",
"0\n",
"8\n",
"None\n"
]
}
],
"source": [
"# Definition for singly-linked list.\n",
"class ListNode:\n",
" def __init__(self, x):\n",
" self.val = x\n",
" self.next = None\n",
"\n",
"class Solution: \n",
" def addTwoNumbers(self, l1, l2):\n",
" \"\"\"\n",
" :type l1: ListNode\n",
" :type l2: ListNode\n",
" :rtype: ListNode\n",
" \"\"\"\n",
" # 用 p1, p2 赋值为 l1 和 l2 ，以防止我们的操作改变原链表\n",
" p1, p2 = l1, l2\n",
" # 创建一个空链表用来返回结果，分别有头结点和尾结点\n",
" head = ListNode(0)\n",
" tail = head\n",
" # carry 表示进位值\n",
" carry = 0\n",
" # 处理两个链表的公共部分，也就是两个链表都不为空的部分\n",
" while p1 and p2:\n",
" # 计算当前位相加的和\n",
" num = p1.val + p2.val + carry\n",
" # 大于 9 ，应该向前进一位\n",
" if num > 9:\n",
" num -= 10\n",
" carry = 1\n",
" else:\n",
" carry = 0\n",
" # 添加结点\n",
" tail.next = ListNode(num)\n",
" # 尾结点向后移动\n",
" tail = tail.next\n",
" # 移动两条链表的公共部分\n",
" p1 = p1.next\n",
" p2 = p2.next\n",
" # 取长链表剩余的部分，也就是未参与上面计算的部分\n",
" if p2:\n",
" # 如果 p2 较长，将 p2 剩余的部分赋值给 p1 ，我们只需要处理 p1 就行了\n",
" p1 = p2\n",
" # 接下来，处理长链表剩余分部分\n",
" while p1:\n",
" # 最近的一位，我们要考虑一下，是否有进位\n",
" num = p1.val + carry\n",
" if num > 9:\n",
" num -= 10\n",
" carry = 1\n",
" else:\n",
" carry = 0\n",
" # 添加结点\n",
" tail.next = ListNode(num)\n",
" tail = tail.next\n",
" \n",
" # 移动我们处理的链表\n",
" p1 = p1.next\n",
" # 如果最后仍然有进位，我们需要再分配一个结点\n",
" if carry:\n",
" # 创建一个 val 为 1 的 ListNode 结点，然后将 tail 向后移动一位\n",
" tail.next = ListNode(1)\n",
" tail = tail.next\n",
" # 将所有的加和及进位都处理完成了，现在我们将链表收尾\n",
" tail.next = None\n",
" # 将 链表的头结点返回\n",
" return head.next # 去除掉我们初始化为 0 的头结点\n",
"\n",
"la = ListNode(2)\n",
"la.next = ListNode(4)\n",
"la.next.next = ListNode(3)\n",
"\n",
"lb = ListNode(5)\n",
"lb.next = ListNode(6)\n",
"lb.next.next = ListNode(4)\n",
"\n",
"s = Solution()\n",
"ss = s.addTwoNumbers(la, lb)\n",
"print(ss.val)\n",
"print(ss.next.val)\n",
"print(ss.next.next.val)\n",
"print(ss.next.next.next) "
]
},
{
"cell_type": "markdown",
"metadata": {},
"source": [
"因此，这个地方我们可以考虑使用递归来求解，具体可以分为以下情况：\n",
"\n",
" - 当两个链表均不为空时，计算两个节点值与上一位进位的和 sum，取 sum 的个位数构建新的节点，更新进位为 sum 的十位数，令本节点的 next 指针指向下一位求和返回的节点。\n",
" - 当两个链表其中一个为空时，计算不为空的节点值与上一位进位的和 sum，更新进位为 sum 的十位数。若进位不为 0 ，取 sum 的个位数构建新节点，令本节点的 next 指针指向下一位求和返回的节点，注意只传递不为空的链表；若进位为 0，则直接更新不为空节点的值为 sum，此时此链表之后的所有高位值都不会更新，因此返回此节点。\n",
" - 若两个链表都为空，判断进位是否为 0。若进位为 0，直接返回 NULL；否则构建值为进位值的新节点，并返回此节点。\n",
" \n",
"> 思路 2\n",
"\n",
" - 跟 plus One ，add Binary 玩的同一个花样，但是相对上个思路来说，更加简单和简洁。\n",
" - 使用递归调用简化算法"
]
},
{
"cell_type": "code",
"execution_count": 2,
"metadata": {},
"outputs": [
{
"name": "stdout",
"output_type": "stream",
"text": [
"7\n",
"0\n",
"8\n",
"None\n"
]
}
],
"source": [
"# Definition for singly-linked list.\n",
"class ListNode:\n",
" def __init__(self, x):\n",
" self.val = x\n",
" self.next = None\n",
"\n",
"class Solution(object):\n",
" def addTwoNumbers(self, l1, l2):\n",
" \"\"\"\n",
" :type l1: ListNode\n",
" :type l2: ListNode\n",
" :rtype: ListNode\n",
" \"\"\"\n",
" # 特殊情况\n",
" if l1 == None:\n",
" return l2\n",
" if l2 == None:\n",
" return l1\n",
" # 如果 相加 小于 10 ，不需要进位\n",
" if l1.val + l2.val < 10:\n",
" l3 = ListNode(l1.val + l2.val)\n",
" l3.next = self.addTwoNumbers(l1.next, l2.next)\n",
" # 相加大于等于 10，需要进位\n",
" elif l1.val + l2.val >= 10:\n",
" l3 = ListNode(l1.val + l2.val - 10)\n",
" tmp = ListNode(1)\n",
" tmp.next = None\n",
" # 递归调用\n",
" l3.next = self.addTwoNumbers(l1.next, self.addTwoNumbers(l2.next ,tmp))\n",
" return l3\n",
" \n",
"la = ListNode(2)\n",
"la.next = ListNode(4)\n",
"la.next.next = ListNode(3)\n",
"\n",
"lb = ListNode(5)\n",
"lb.next = ListNode(6)\n",
"lb.next.next = ListNode(4)\n",
"\n",
"s = Solution()\n",
"ss = s.addTwoNumbers(la, lb)\n",
"print(ss.val)\n",
"print(ss.next.val)\n",
"print(ss.next.next.val)\n",
"print(ss.next.next.next)"
]
}
],
"metadata": {
"kernelspec": {
"display_name": "Python 3",
"language": "python",
"name": "python3"
},
"language_info": {
"codemirror_mode": {
"name": "ipython",
"version": 3
},
"file_extension": ".py",
"mimetype": "text/x-python",
"name": "python",
"nbconvert_exporter": "python",
"pygments_lexer": "ipython3",
"version": "3.6.3"
}
},
"nbformat": 4,
"nbformat_minor": 2
}
| 2024-02-03T01:26:59.872264 | https://example.com/article/2624 |
Q:
Calling specific namespace and class using Strings
I am currently writing a program in C#, this program has a folder called Classes, many subfolders named a - f, and actual cs files within that folder named aa - cc.
a-f are namespaces
aa-cc are classes.
So if I wanted to invoke a method from Classes\b\bb.cs I'd have to type every time
b.bb,methodName();
It will also generate two Strings which will decide what we are going to be executing.
String myType = "b";
String myClass = "bb";
String toReturn = "";
There are many combinations of myType and myClass so I've had to write a lot of if loops
if (myType.equals("b") && myClass.equals("bb") return toReturn = b.bb.myMethod();
if (myType.equals("b") && myClass.equals("aa") return toReturn = b.aa.myMethod();
this is quite a lot of typing and I feel like there is an easier way to do this since I already know what know what namespace I want to access and what method I want to call.
Is there any way I could do something like
myType.myClass.myMethod()
where myType is the namespace, and myClass is the class I wish to call. This would avoid me typing out ever possible combination.
A:
Improved sample with delegates. Homework: add hash to store delegates in GetDelegate method.
using System;
using System.Collections.Generic;
using System.Linq;
using System.Reflection;
using TestConsole.Data;
namespace NamespaceA
{
public class ClassAB
{
public void MyMethod()
{
Console.WriteLine("You invoke NamespaceA.ClassAB.MyMethod");
}
public static void MyStaticMethod()
{
Console.WriteLine("You invoke NamespaceA.ClassAB.MyStaticMethod");
}
}
}
namespace TestConsole
{
public delegate void DoSomethingUseful(); // same as Action delegate
class Program
{
/// <summary>
/// create delegate
/// </summary>
/// <param name="namespace"> namespace name </param>
/// <param name="class"> class name </param>
/// <param name="method"> method name </param>
/// <returns></returns>
public static DoSomethingUseful GetDelegate(string @namespace, string @class, string method)
{
// common argument checks
if (@namespace == null) throw new ArgumentNullException("namespace");
if (@class == null) throw new ArgumentNullException("class");
if (method == null) throw new ArgumentNullException("method");
// find class
Type type = Type.GetType(@namespace + "." + @class);
if (type == null) throw new Exception("type not found");
// find method
MethodInfo methodInfo = type.GetMethod(method);
if (methodInfo == null) throw new Exception("method not found");
// create the delegate
return (DoSomethingUseful)Delegate.CreateDelegate(typeof(DoSomethingUseful), methodInfo.IsStatic ? null : Activator.CreateInstance(type), methodInfo);
}
static void Main(string[] args)
{
// creating delegates
DoSomethingUseful methodA = GetDelegate("NamespaceA", "ClassAB", "MyMethod");
DoSomethingUseful methodB = GetDelegate("NamespaceA", "ClassAB", "MyStaticMethod");
// usage
methodA();
methodB();
Console.WriteLine();
Console.WriteLine("Press any key to continue...");
Console.ReadKey();
}
}
}
| 2024-01-21T01:26:59.872264 | https://example.com/article/8880 |
NJ Voices Guest blog: Must-see storiestag:blog.nj.com,2014:/njv_guest_blog/21682014-01-31T19:40:04ZNJ Voices: Opinions from New JerseyMovable Type Enterprise 4.29-advanceChristie's pick raises concern: Ethics Commission must be independent (Opinion)tag:blog.nj.com,2014:/njv_guest_blog/2168.121052472014-01-31T19:40:04Z2014-01-31T20:43:57ZGov. Chris Christie appointed a trusted aide to serve as executive director of the State Ethics Commission. How can she be an independent investigator?Star-Ledger Guest Columnisthttp://connect.nj.com/user/njoslguest/index.html
Gov. Chris Christie appointed a trusted aide to serve as executive director of the State Ethics Commission. How can she be an independent investigator?
Opinion: I exposed priest in sexting sting. Now church must reform. tag:blog.nj.com,2013:/njv_guest_blog//2168.116850662013-11-21T11:00:05Z2013-11-22T18:09:09ZFor sexual abuse victims, the church is no sanctuary.Star-Ledger Guest Columnisthttp://connect.nj.com/user/njoslguest/index.html
For sexual abuse victims, the church is no sanctuary.
Why legislation for marriage equality in N.J. still matters: Opiniontag:blog.nj.com,2013:/njv_guest_blog//2168.114775912013-10-22T10:10:44Z2013-10-22T11:47:35ZThe New Jersey Supreme Court's decision leaves key issues unresolved.Star-Ledger Guest Columnisthttp://connect.nj.com/user/njoslguest/index.html
The New Jersey Supreme Court's decision leaves key issues unresolved.
Don't let N.J. come in last in marriage equality: Opiniontag:blog.nj.com,2013:/njv_guest_blog//2168.114449482013-10-17T10:21:18Z2013-10-17T10:22:18ZState lawmakers can and should beat the courts and take the lead on same-sex marriageStar-Ledger Guest Columnisthttp://connect.nj.com/user/njoslguest/index.html
State lawmakers can and should beat the courts and take the lead on same-sex marriage
Was N.J. smarter than the storm if Sandy was responsible for boardwalk fire? Opiniontag:blog.nj.com,2013:/njv_guest_blog//2168.113186542013-09-27T10:05:00Z2013-09-27T11:54:25ZIt appears that the rush to rebuild and reopen the Seaside boardwalk lacked due diligence and careful execution. Star-Ledger Guest Columnisthttp://connect.nj.com/user/njoslguest/index.html
It appears that the rush to rebuild and reopen the Seaside boardwalk lacked due diligence and careful execution.
Pope Francis takes the long view for Catholic church: Opiniontag:blog.nj.com,2013:/njv_guest_blog//2168.112819622013-09-23T11:01:34Z2013-09-23T11:12:33ZPope Francis believes individual Catholics must believe the church cares about them no matter who they are.Star-Ledger Guest Columnisthttp://connect.nj.com/user/njoslguest/index.html
Pope Francis believes individual Catholics must believe the church cares about them no matter who they are.
Taking my son to college, where technology has replaced serendipity: Opiniontag:blog.nj.com,2013:/njv_guest_blog//2168.111579582013-09-01T09:44:35Z2013-09-01T09:44:47ZCompared with the tools Hayden has at his disposal, I went to college in the Stone Age. But I wonder what may be lost.Star-Ledger Guest Columnisthttp://connect.nj.com/user/njoslguest/index.html
Compared with the tools Hayden has at his disposal, I went to college in the Stone Age. But I wonder what may be lost.
Booker's biggest obstacle? Maybe the 'single stigma': Opiniontag:blog.nj.com,2013:/njv_guest_blog//2168.111515282013-08-30T11:00:26Z2013-08-30T12:47:15ZHis choice to remain single is a valid lifestyle decision that shouldn’t be a factor as to whether he would be an effective leader.Star-Ledger Guest Columnisthttp://connect.nj.com/user/njoslguest/index.html
His choice to remain single is a valid lifestyle decision that shouldn’t be a factor as to whether he would be an effective leader.
In March on Washington, a Newark rabbi's words resonated with all: Opiniontag:blog.nj.com,2013:/njv_guest_blog//2168.111374902013-08-28T10:34:41Z2013-08-28T10:36:14ZJoachim Prinz spoke as a fellow American, an American who had seen utter horror up close in Nazi Germany.Star-Ledger Guest Columnisthttp://connect.nj.com/user/njoslguest/index.html
Joachim Prinz spoke as a fellow American, an American who had seen utter horror up close in Nazi Germany.
The forgotten political feud that spawned the Jersey Devil: Opiniontag:blog.nj.com,2013:/njv_guest_blog//2168.110810552013-08-18T11:00:00Z2013-08-18T11:00:29ZA complex political animal had been transformed into a cartoonish, pedestrian and childish monster that never existed.Star-Ledger Guest Columnisthttp://connect.nj.com/user/njoslguest/index.html
A complex political animal had been transformed into a cartoonish, pedestrian and childish monster that never existed.
An almost-forgotten nuclear hero: Opiniontag:blog.nj.com,2013:/njv_guest_blog//2168.108780572013-07-09T10:06:19Z2013-07-09T10:08:10ZDespite her key role in the discovery of nuclear fission, Lise Meitner did not share in the 1945 Nobel Prize.Star-Ledger Guest Columnisthttp://connect.nj.com/user/njoslguest/index.html
Despite her key role in the discovery of nuclear fission, Lise Meitner did not share in the 1945 Nobel Prize.
In defense of Hermann serving as Rutgers AD: John Farmer Jr.tag:blog.nj.com,2013:/njv_guest_blog//2168.106693862013-06-02T15:14:00Z2013-06-02T18:39:21ZLook at her record. There is no pervasive pattern of abusive coaching — just a record of pioneering achievement.Star-Ledger Guest Columnisthttp://connect.nj.com/user/njoslguest/index.html
Look at her record. There is no pervasive pattern of abusive coaching — just a record of pioneering achievement.
A player on Hermann’s volleyball team speaks outtag:blog.nj.com,2013:/njv_guest_blog//2168.106704102013-06-02T09:40:26Z2013-06-02T12:06:27ZA lot has happened since then. We all moved on and so has she. Star-Ledger Guest Columnisthttp://connect.nj.com/user/njoslguest/index.html
A lot has happened since then. We all moved on and so has she.
How the swastika spread from suburban New Jersey: Opiniontag:blog.nj.com,2013:/njv_guest_blog//2168.104800612013-05-05T12:00:00Z2013-05-05T12:01:46ZHow did one family turn a sleepy town into a hive of espionage and Nazism?Star-Ledger Guest Columnisthttp://connect.nj.com/user/njoslguest/index.html
How did one family turn a sleepy town into a hive of espionage and Nazism?
Where's the TV coverage of the Paralympics?tag:blog.nj.com,2012:/njv_guest_blog//2168.88574382012-08-19T12:00:00Z2012-08-17T21:18:14ZIf you thought the players in the Olympics played rough, watch a game of wheelchair basketball.NJ Voices Guest Blogger/For NJ.comhttp://connect.nj.com/user/njonjvoices/index.html
If you thought the players in the Olympics played rough, watch a game of wheelchair basketball.
A former classmate remembers Kendell Spear, a young man taken too soontag:blog.nj.com,2012:/njv_guest_blog//2168.87480092012-07-29T09:45:46Z2012-07-28T00:00:46ZGrowing up in the war zone of Newark, I've ignored crime. Kendell's death changed everything.NJ Voices Guest Blogger/For NJ.comhttp://connect.nj.com/user/njonjvoices/index.html
Growing up in the war zone of Newark, I've ignored crime. Kendell's death changed everything.
Mount Laurel affordable housing decision made dreams come truetag:blog.nj.com,2012:/njv_guest_blog//2168.81466922012-04-22T10:01:52Z2012-04-22T20:36:11ZForty years after the beginning of the landmark Mount Laurel court decisions, affordable housing has been a life-changing move for some New Jerseyans.Linda Ocasio/The Star-Ledgerhttp://connect.nj.com/user/locasio/index.html
Forty years after the beginning of the landmark Mount Laurel court decisions, affordable housing has been a life-changing move for some New Jerseyans.
East Orange High School's disappeared swimming pool a hidden symbol for civil rightstag:blog.nj.com,2012:/njv_guest_blog//2168.75970212012-01-20T19:00:47Z2012-01-20T19:12:30ZCivil rights hero Robert L. Carter, who died this month, graduated from East Orange High School in 1933, where he protested the segregation of the school's swimming pool -- the consequences of which sparked an urban legend that lasted for decades.Star-Ledger Guest Columnisthttp://connect.nj.com/user/njoslguest/index.html
Civil rights hero Robert L. Carter, who died this month, graduated from East Orange High School in 1933, where he protested the segregation of the school's swimming pool -- the consequences of which sparked an urban legend that lasted for decades.
Stephen Sweeney: Time for N.J. to allow same-sex marriagetag:blog.nj.com,2012:/njv_guest_blog//2168.75866202012-01-18T12:44:09Z2012-01-18T23:43:06ZSenate President Stephen Sweeney says the first bill introduced in the N.J. legislature will be devoted to achieving marriage equality.Star-Ledger Guest Columnisthttp://connect.nj.com/user/njoslguest/index.html
Senate President Stephen Sweeney says the first bill introduced in the N.J. legislature will be devoted to achieving marriage equality.
The real national debt: What America owes its veteranstag:blog.nj.com,2011:/njv_guest_blog//2168.7268783.201111102021172011-11-11T11:05:23Z2011-11-11T01:21:17ZThis Veteran's Day, ask yourself: Are we supporting our veterans even half as well as they have supported us? Star-Ledger Guest Columnisthttp://connect.nj.com/user/njoslguest/index.html
This Veteran's Day, ask yourself: Are we supporting our veterans even half as well as they have supported us? | 2023-11-11T01:26:59.872264 | https://example.com/article/8039 |
Creagh Icefall
Creagh Icefall () is an icefall at the head of Creagh Glacier in the Wilkniss Mountains, Victoria Land. It was named by the Advisory Committee on Antarctic Names in 1994 in association with Creagh Glacier.
References
Category:Icefalls of Antarctica
Category:Landforms of Victoria Land
Category:Scott Coast | 2023-09-09T01:26:59.872264 | https://example.com/article/5322 |
Mari language (Madang Province)
Mari, or Hop, is a minor Austronesian language of Madang Province, Papua New Guinea. It is spoken in the four villages of Bumbu (), Bubirumpun (), Musuam (), and Sangkiang () in Usino Rural LLG of the Ramu valley.
References
Category:Markham languages
Category:Languages of Papua New Guinea
Category:Languages of Madang Province | 2023-11-08T01:26:59.872264 | https://example.com/article/3509 |
General Question
Why did my letter c not work 15 minutes ago?
I have a laptop corei5 Aspire S3 windows 8.1, and my letter c stopped working for no apparent reason. I did a virus scan and it didn’t find any viruses. qwertyuiopasdfghjklzxcvbnm works for now. I need the letter c for my password, So I could use help in case it happens again.
I vote that there are some food bits under the keys. I clean my pc keyboard regularly by turning the laptop off, tilting it sideways, and blowing on the keys with compressed air. It’s amazing how much stuff flies out of there.
How old is the laptop? Keypads do wear out. When mine went south once, it was first evidenced by a “drifting” cursor on the monitor screen, even though my mouse was perfectly still and I wasn’t operating the joystick or touchpad. Later, as my keypad worsened (and I still didn’t understand what was wrong) my center keys stopped working: in particular, I, J and K started to fail frequently.
At that point I called IT support (it was a work machine), and a half-hour later I had a new and perfectly functioning keypad (the surface under the keys that the keys operate) installed.
Your issue may very well be a foreign object under the key. I’d try @LuckyGuy‘s recommendation as the fix that is least intrusive and least likely to cause damage. Removing keys can be a problem; I’ve seen the attachment parts break as that was attempted. | 2024-03-04T01:26:59.872264 | https://example.com/article/8296 |
The present invention relates to an apparatus for supplying cheese coagulum to an oblong prepressing vat or a similar container, comprising a distributor unit arranged generally crosswise of the longitudinal direction of the container and being reciprocable along the container, with the distributor unit being operable to receive a mixture of whey and cheese coagulum at one or more places along the length of the unit and, via an associated distributor container, to distribute this mixture over the length of the distributor unit in such a manner that the mixture may flow off from the distributor container in a broad, relatively even flow all over the length of the distributor container, which container is equipped with rotating wing rollers for sluicing out the mixture from the receiving place or places to and beyond elongated outlet edge means of the container.
What is endeavoured hereby, is to effect a highly uniform distribution or depositing of the cheese coagulum in the vat, throughout the area thereof, such that it is ensured that the coagulum is laid out with an even thickness, which, later on in the cheese production process, will result in the production of cheese members of equal thickness as required for a still later cutting off of cheese slices of a well defined width. This requirement is pronounced in commercial practice, particularly for the cheeses delivered to restaurants and cheese slice packing enterprises.
The reciprocation movement of the distributor unit along the prepressing vat will serve to ensure an even distribution of the coagulum mixture along the length of the vat, particularly as towards the end of the vat filling process the coagulum contents of the mixture will gradually decrease, when the mixture is delivered from a conventional curdling tank. However, the desired result will not be obtained unless the coagulum distribution is uniform also in the cross direction of the vat, i.e. in the length direction of the distributor unit.
It is difficult to obtain a uniform distribution of the coagulum in that direction, already because the coagulum, which is only slightly heavier than the whey, can move around in the whey in an uncontrolled manner, particularly by turbulence created at the place or places where the mixture is supplied to the distributor.
A principally good solution to this problem has been found to be the use of the wing rollers, which operate to lift the mixture up along a correspondingly arched wall portion of the distributor container from a bottom inlet area to a horizontal overflow edge thereof, whereby the mixture will be trapped temporarily between the consecutive pairs of wings and thus be shielded off from the turbulent mixture adjacent the container bottom before the trapped mixture is lifted over the overflow edge; in this manner the coagulum in the trapped or isolated mixture portions as extending all the way along the distributor container will get the opportunity to fall to rest before being delivered to the vat, and hereby the coagulum tends to distribute itself evenly along the container.
It has then been found, however, that by the passage of coagulum lumps over the overflow edge a build-up of such lumps may occur on the edge itself, whereby the free overflow may be locally obstructed, resulting in groove formations in the laid out coagulum layer in the vat.
It is the purpose of the present invention to provide a distributor apparatus of the type referred to, by which a flow obstructing lump build-up will be practically impossible and according to the invention this is achieved by constructing The apparatus such that wing rollers are mounted so as to engage with each other at an intermediate height level of the distributor container such as, for example, between an upper mixture receiving part of the container and a lower, slot-shaped bottom outlet thereof. The wing rollers are rotatable for sluicing down the mixture along respective opposed part-cylindrical bottom wall portions of the container to a common outlet space or chamber just above the slot-shaped bottom outlet.
Accordingly, the invention departs from the principle of bringing the mixture to an overflow edge, as instead of this it is let out through a bottom outlet slot with a flow intensity determined by the operation speed of the wing rollers; these, still acting to successively trap the mixture portions for a good coagulum distribution therein, will guide the mixture downwardly and inwardly to a delivery space just above the outlet slot, from which the mixture may then fall freely down into the vat. The wings will sweep along the arched container bottom almost entirely down to the respective opposed edges of the outlet slot, such that there will be no area in which the coagulum gets an opportunity to be supported on an underlying surface such as an overflow edge.
In the following the invention is described in more detail with reference to the accompanying drawing. | 2024-01-09T01:26:59.872264 | https://example.com/article/3165 |
Q:
How to save dinamically array in core data or realm in iOS And how to compare this array
I have an array
var names:[String]=["kate","son","viktor"]
I want to save this array in core data or Realm. This array dynamically changed
var names:[String]=["kate","son","viktor","sam"]
How to compare this arrays and print changes. For example: changes for names "Sam". Thanks for any help(idea) or links.
A:
In Realm, you could simply serialize/deserialize the array to Data (or String), like this:
class SomeModel: Object {
dynamic var _names: Data!
var names: [String] {
set(value) {
try! realm.write {
_properties = try! JSONSerialization.data(withJSONObject: value, options: [])
}
}
get {
guard _names != nil else { return [] }
return try! JSONSerialization.jsonObject(with: _names, options: []) as? [String] ?? []
}
}
}
This will store your array in Realm, but will not allow you to sort or query using the names in the array, obviously.
You probably better store each name in a proper model object and create a one-to-many property in the base object (using Realm's List)
| 2023-09-28T01:26:59.872264 | https://example.com/article/8016 |
Q:
c++ segmentation fault trying to access vector
Im trying to create a adjacency representation of a graph.
I wrote a small program using vectors of vectors , however I keep getting "segmentation fault" but the compiler(clang++ version 5.0.1 on Windows) it seems wereever I try to access the vector vertex_matrix its giving a segmentation fault, why is it not being instantiated?
Here is the header:
#ifndef GRAPH_MATRIX
#define GRAPH_MATRIX
#include <vector>
//header for graph represented via adjacency matrix with minimal functionality
class graph
{
public:
graph(int);
~graph();
void add_edge(int v1, int v2, int weight);
void print_graph();
private:
std::vector<std::vector<int>> vertex_matrix;
int num_of_vertices;
int num_of_edges;
};
#endif
Here is the cpp implementation:
#include <iostream>
#include "graph_matrix.h"
#include <climits>
using namespace std;
//header for graph represented via adjacency matrix with minimal functionality
graph::graph(int _num_of_vertices) : num_of_vertices(_num_of_vertices)
{
if (_num_of_vertices==0)
{
_num_of_vertices=10;
}
for (int i = 0; i < _num_of_vertices; i++)
{
vertex_matrix[i]=(vector<int> (_num_of_vertices,INT_MAX));
}
}
graph::~graph()
{
vertex_matrix.clear();
}
void graph::add_edge(int v1, int v2, int weight)
{
//vertex_matrix[v1-1][v2-1] == INT_MAX
vector<int> columnVector = vertex_matrix[v1-1];
if (columnVector[v2-1] == INT_MAX)
{
columnVector[v2-1] = weight;
}
}
void graph::print_graph()
{
cout << "vertex_matrix size:" << vertex_matrix.size() << endl;
for (int i=0; i< num_of_vertices; i++)
{
for (int j = 0; j < num_of_vertices; j++)
{
//vertex_matrix[i][j]
std::vector<int> columnVector = vertex_matrix[i];
if (columnVector[j] != INT_MAX)
{
std::cout << columnVector[j] ;
}
else
{
std::cout << "0";
}
}
std::cout << endl;
}//end for printing
}
Here is the main entry:
#include <iostream>
#include "graph_matrix.h"
using namespace std;
int main ()
{
std::cout << " Matrix representation of graph" << std::endl;
graph _graph(4);
_graph.add_edge(1,2,1);
_graph.add_edge(2,3,1);
_graph.add_edge(3,1,1);
_graph.add_edge(3,3,1);
_graph.add_edge(3,4,1);
_graph.add_edge(4,0,0);
_graph.print_graph();
}
I edited the above code to use pass by reference, however the matrix still prints as 0's.
Please help with pass by reference, updates below:
Header:
#ifndef GRAPH_MATRIX
#define GRAPH_MATRIX
#include <vector>
//header for graph represented via adjacency matrix with minimal functionality
class graph
{
public:
graph(int);
~graph();
void add_edge(int v1, int v2, int weight,std::vector<std::vector<int>> & matrix);
void print_graph();
std::vector<std::vector<int>> vertex_matrix;
private:
int num_of_vertices;
int num_of_edges;
};
#endif
Cpp file:
#include <iostream>
#include "graph_matrix.h"
#include <climits>
using namespace std;
//header for graph represented via adjacency matrix with minimal functionality
graph::graph(int _num_of_vertices) : num_of_vertices(_num_of_vertices) {
if (num_of_vertices == 0) {
num_of_vertices = 10;
}
for (int i = 0; i < num_of_vertices; i++) {
std::vector<std::vector<int>>& matrix = vertex_matrix;
matrix.push_back(vector<int> (num_of_vertices, INT_MAX));
}
}
graph::~graph() {
std::vector<std::vector<int>>& matrix = vertex_matrix;
matrix.clear();
}
void graph::add_edge(int v1, int v2, int weight,std::vector<std::vector<int>> & _matrix) {
//vertex_matrix[v1-1][v2-1] == INT_MAX
vector<int> columnVector = _matrix[v1 - 1];
if (columnVector[v2 - 1] == INT_MAX) {
columnVector[v2 - 1] = weight;
}
}
void graph::print_graph() {
std::vector<std::vector<int>>& matrix = vertex_matrix;
for (int i = 0; i < matrix.size(); i++) {
for (int j = 0; j < matrix.size(); j++) {
//vertex_matrix[i][j]
std::vector<int> columnVector = matrix[i];
if (columnVector[j] != INT_MAX) {
std::cout << columnVector[j];
} else {
std::cout << "0";
}
}
std::cout << endl;
}//end for printing
}
main:
#include <iostream>
#include "graph_matrix.h"
using namespace std;
int main ()
{
std::cout << " Matrix representation of graph" << std::endl;
graph _graph(4);
std::vector<std::vector<int>>& m = _graph.vertex_matrix;
_graph.add_edge(1,2,1,m);
_graph.add_edge(2,3,1,m);
_graph.add_edge(3,1,1,m);
_graph.add_edge(3,3,1,m);
_graph.add_edge(3,4,1,m);
_graph.add_edge(4,0,0,m);
_graph.print_graph();
}
Any help will be appreciated.
Thanks
A:
You create an empty vector and then try to access elements in it. Change your constructor to
graph::graph(size_t _num_of_vertices) :
vertex_matrix(
std::vector<std::vector<int>>(
_num_of_vertices,std::vector<int>(_num_of_vertices)
)
)
{}
to create a correctly sized vector.
Also in case _num_vertices == 0 you set it to 10 but thats after you initialized the member num_vertices so you leave the object in an inconsistent state. There are different ways to fix that, I would probably just throw an exception when the number of vertices passed is zero, or just ignore it. User wants a zero sized matrix? Why not?
Moreover the size should be unsigned not signed, there is size_t for container sizes. Even better you shouldnt have that member at all, because a vector already knows its size, the only reason to repeat that information is to introduce mistakes ;)
| 2024-07-20T01:26:59.872264 | https://example.com/article/8382 |
Washington, D.C. — Never has the mainstream media bias been more evident than in the last 48 hours, as all three major broadcast networks have given heavy coverage to the allegations made against Alabama GOP Senate candidate Roy Moore, while the ongoing federal corruption trial of New Jersey Democratic Senator Bob Menendez—who was accused of hiring child prostitutes—has been largely ignored by these same outlets.
Menendez, who has been on trial for 65 days, is charged with taking tens of thousands of dollars in bribes in exchange for political favors. He faces a total of six counts of bribery, three counts of honest services fraud, one count of conspiracy, one count of interstate travel to carry out bribery and one count of making false statements on his congressional financial disclosures to conceal the crimes.
Despite being on trial for over two months, “ABC World News Tonight, CBS Evening News and NBC Nightly News haven’t even mentioned the trial once. NBC’s Today also hasn’t covered this trial at all, while ABC’s Good Morning America and CBS This Morning have managed to give it one story each (1 minute, 48 seconds for ABC and 22 seconds for CBS),” according to the Media Research Center (MRC).
In fact, in the past 24 hours, the same networks that never once in 65 days mentioned Menendez, and the serious accusations against him – including the allegation of hiring child prostitutes, “spent 24 minutes and 36 seconds on serious allegations against Alabama Senate candidate Roy Moore.”
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According to a report by the Media Research Center:
The three evening news shows each spent about two-and-a-half minutes on the Moore scandal (ABC’s World News Tonight: 2 minutes, 48 seconds; CBS Evening News: 2 minutes, 46 seconds; NBC Nightly News, 2 minutes, 38 seconds). Good Morning America spent the most time on Moore with 7 minutes. CBS This Morning came next with 5 minutes and 22 seconds, while NBC’s Today came in third with 4 minutes, 2 seconds.
To put things into perspective, this is the first time a sitting U.S. Senator has faced a corruption trial since 1981.
Additionally, if Menendez is convicted and forced out of office prior to Jan. 16, 2018, GOP Governor Chris Christie will appoint a replacement—likely flipping a Democratic Senate seat to a Republican one.
The jury has been deliberating Menendez’s fate since Oct. 30.
These facts, along with the salacious details uncovered during the course of the investigation into Menendez, would seemingly be exactly the type of story political pundits in the media salivate over—yet there has largely been silence from the mass media presstitutes.
While the media has a duty to cover the sexual harassment allegations against Alabama Senatorial Candidate Roy Moore, the fact that these same outlets have chosen to give such extremely disparate coverage to Menendez’s trial reeks of liberal media bias.
Regardless of whether a Democrat or a Republican, the media has a duty to share their investigations with the public.
The selective outrage of the mainstream media is unmistakable in the case of these two men and clearly evidenced by the disproportionate coverage given to their alleged indiscretions.
It is inexcusable that these two men, both alleged to have engaged in inappropriate activity with underage parties, are not treated in the same manner by the mainstream media—which speaks volumes as to how the mass media attempts to propagandize Americans into a false sense of reality.
Please share this story to help others clearly see how the media attempts to mold perceptions as to benefit those that largely share their political ideology!
You Might Like
Courtesy of The Free Thought Project
Jay Syrmopoulos is a geopolitical analyst, freethinker, and ardent opponent of authoritarianism. He is currently a graduate student at the University of Denver pursuing a masters in Global Affairs and holds a BA in International Relations. Jay’s writing has been featured on both mainstream and independent media – and has been viewed tens of millions of times. You can follow him on Twitter @SirMetropolis and on Facebook at SirMetropolis. | 2024-06-19T01:26:59.872264 | https://example.com/article/6648 |
package com.novemberain.quartz.mongodb
import org.quartz.Job
import org.quartz.JobBuilder
import org.quartz.JobExecutionContext
import org.quartz.JobExecutionException
import org.quartz.TriggerBuilder
import spock.lang.Specification
class LoadBalancingTest extends Specification {
def setup() {
MongoHelper.purgeCollections()
}
static counter = Collections.synchronizedList([])
public static class SharedJob implements Job {
@Override
void execute(JobExecutionContext context) throws JobExecutionException {
def id = context.getScheduler().getSchedulerInstanceId()
println("Shared Job executed by: ${id}")
counter.add(id)
Thread.sleep(2000)
}
}
def 'should execute the job only once'() {
given:
counter.clear()
def cluster = QuartzHelper.createCluster('duch', 'rysiek')
def job = JobBuilder.newJob()
.ofType(SharedJob)
.withIdentity('job1', 'g1')
.build()
def trigger = TriggerBuilder.newTrigger()
.startAt(new Date(System.currentTimeMillis() + 1000l))
.withIdentity('t1', 'g1')
.build()
when:
cluster.first().scheduleJob(job, trigger)
Thread.sleep(7000)
then:
QuartzHelper.shutdown(cluster)
counter.size() == 1
}
} | 2024-07-31T01:26:59.872264 | https://example.com/article/5788 |
import FWCore.ParameterSet.Config as cms
process = cms.Process("PROD")
process.load("SimGeneral.HepPDTESSource.pdt_cfi")
process.load("Configuration.Geometry.GeometryExtended2026D41Reco_cff")
#process.load("Geometry.HGCalCommonData.testHGCV12XML_cfi")
#process.load("Geometry.HGCalCommonData.hgcalParametersInitialization_cfi")
#process.load("Geometry.HGCalCommonData.hgcalNumberingInitialization_cfi")
#process.load("Geometry.CaloEventSetup.HGCalV9Topology_cfi")
#process.load("Geometry.HGCalGeometry.HGCalGeometryESProducer_cfi")
process.load('FWCore.MessageService.MessageLogger_cfi')
if hasattr(process,'MessageLogger'):
process.MessageLogger.categories.append('HGCalGeom')
process.load("IOMC.RandomEngine.IOMC_cff")
process.RandomNumberGeneratorService.generator.initialSeed = 456789
process.source = cms.Source("EmptySource")
process.generator = cms.EDProducer("FlatRandomEGunProducer",
PGunParameters = cms.PSet(
PartID = cms.vint32(14),
MinEta = cms.double(-3.5),
MaxEta = cms.double(3.5),
MinPhi = cms.double(-3.14159265359),
MaxPhi = cms.double(3.14159265359),
MinE = cms.double(9.99),
MaxE = cms.double(10.01)
),
AddAntiParticle = cms.bool(False),
Verbosity = cms.untracked.int32(0),
firstRun = cms.untracked.uint32(1)
)
process.maxEvents = cms.untracked.PSet(
input = cms.untracked.int32(1)
)
process.prodEE = cms.EDAnalyzer("HGCalGeomLocaterTester",
Detector = cms.string("HGCalEESensitive"),
)
process.prodHEF = process.prodEE.clone(
Detector = "HGCalHESiliconSensitive",
)
process.p1 = cms.Path(process.generator*process.prodEE*process.prodHEF)
| 2024-02-17T01:26:59.872264 | https://example.com/article/7772 |
/* NetHack 3.6 mhmsgwnd.c $NHDT-Date: 1432512802 2015/05/25 00:13:22 $ $NHDT-Branch: master $:$NHDT-Revision: 1.20 $ */
/* Copyright (C) 2001 by Alex Kompel */
/* NetHack may be freely redistributed. See license for details. */
#include "winMS.h"
#include "mhmsgwnd.h"
#include "mhmsg.h"
#include "mhcmd.h"
#include "mhfont.h"
#include "mhcolor.h"
#define MSG_WRAP_TEXT
#define MSG_VISIBLE_LINES max(iflags.wc_vary_msgcount, 2)
#define MAX_MSG_LINES 32
#define MSG_LINES (int) min(iflags.msg_history, MAX_MSG_LINES)
#define MAXWINDOWTEXT 200
struct window_line {
int attr;
char text[MAXWINDOWTEXT];
};
typedef struct mswin_nethack_message_window {
size_t max_text;
struct window_line window_text[MAX_MSG_LINES];
int xChar; /* horizontal scrolling unit */
int yChar; /* vertical scrolling unit */
int xUpper; /* average width of uppercase letters */
int xPos; /* current horizontal scrolling position */
int yPos; /* current vertical scrolling position */
int xMax; /* maximum horizontal scrolling position */
int yMax; /* maximum vertical scrolling position */
int xPage; /* page size of horizontal scroll bar */
int lines_last_turn; /* lines added during the last turn */
int dont_care; /* flag the user does not care if messages are lost */
} NHMessageWindow, *PNHMessageWindow;
static TCHAR szMessageWindowClass[] = TEXT("MSNHMessageWndClass");
LRESULT CALLBACK NHMessageWndProc(HWND, UINT, WPARAM, LPARAM);
static void register_message_window_class();
static void onMSNHCommand(HWND hWnd, WPARAM wParam, LPARAM lParam);
static void onMSNH_VScroll(HWND hWnd, WPARAM wParam, LPARAM lParam);
#ifndef MSG_WRAP_TEXT
static void onMSNH_HScroll(HWND hWnd, WPARAM wParam, LPARAM lParam);
#endif
static COLORREF setMsgTextColor(HDC hdc, int gray);
static void onPaint(HWND hWnd);
static void onCreate(HWND hWnd, WPARAM wParam, LPARAM lParam);
#ifdef USER_SOUNDS
extern void play_sound_for_message(const char *str);
#endif
HWND
mswin_init_message_window()
{
static int run_once = 0;
HWND ret;
DWORD style;
if (!run_once) {
register_message_window_class();
run_once = 1;
}
#ifdef MSG_WRAP_TEXT
style = WS_BORDER | WS_CHILD | WS_CLIPSIBLINGS | WS_VSCROLL;
#else
style = WS_BORDER | WS_CHILD | WS_CLIPSIBLINGS | WS_VSCROLL | WS_HSCROLL;
#endif
ret = CreateWindow(
szMessageWindowClass, /* registered class name */
NULL, /* window name */
style, /* window style */
0, /* horizontal position of window */
0, /* vertical position of window */
0, /* window width */
0, /* window height - set it later */
GetNHApp()->hMainWnd, /* handle to parent or owner window */
NULL, /* menu handle or child identifier */
GetNHApp()->hApp, /* handle to application instance */
NULL); /* window-creation data */
if (!ret)
panic("Cannot create message window");
return ret;
}
void
register_message_window_class()
{
WNDCLASS wcex;
ZeroMemory(&wcex, sizeof(wcex));
wcex.style = CS_NOCLOSE;
wcex.lpfnWndProc = (WNDPROC) NHMessageWndProc;
wcex.cbClsExtra = 0;
wcex.cbWndExtra = 0;
wcex.hInstance = GetNHApp()->hApp;
wcex.hIcon = NULL;
wcex.hCursor = LoadCursor(NULL, IDC_ARROW);
wcex.hbrBackground = mswin_get_brush(NHW_MESSAGE, MSWIN_COLOR_BG);
wcex.lpszMenuName = NULL;
wcex.lpszClassName = szMessageWindowClass;
RegisterClass(&wcex);
}
LRESULT CALLBACK
NHMessageWndProc(HWND hWnd, UINT message, WPARAM wParam, LPARAM lParam)
{
switch (message) {
case WM_CREATE:
onCreate(hWnd, wParam, lParam);
break;
case WM_MSNH_COMMAND:
onMSNHCommand(hWnd, wParam, lParam);
break;
case WM_PAINT:
onPaint(hWnd);
break;
case WM_SETFOCUS:
SetFocus(GetNHApp()->hMainWnd);
break;
#ifndef MSG_WRAP_TEXT
case WM_HSCROLL:
onMSNH_HScroll(hWnd, wParam, lParam);
break;
#endif
case WM_VSCROLL:
onMSNH_VScroll(hWnd, wParam, lParam);
break;
case WM_DESTROY: {
PNHMessageWindow data;
data = (PNHMessageWindow) GetWindowLong(hWnd, GWL_USERDATA);
free(data);
SetWindowLong(hWnd, GWL_USERDATA, (LONG) 0);
} break;
case WM_SIZE: {
SCROLLINFO si;
int xNewSize;
int yNewSize;
PNHMessageWindow data;
data = (PNHMessageWindow) GetWindowLong(hWnd, GWL_USERDATA);
xNewSize = LOWORD(lParam);
yNewSize = HIWORD(lParam);
if (xNewSize > 0 || yNewSize > 0) {
#ifndef MSG_WRAP_TEXT
data->xPage = xNewSize / data->xChar;
data->xMax = max(0, (int) (1 + data->max_text - data->xPage));
data->xPos = min(data->xPos, data->xMax);
ZeroMemory(&si, sizeof(si));
si.cbSize = sizeof(si);
si.fMask = SIF_RANGE | SIF_PAGE | SIF_POS;
si.nMin = 0;
si.nMax = data->max_text;
si.nPage = data->xPage;
si.nPos = data->xPos;
SetScrollInfo(hWnd, SB_HORZ, &si, TRUE);
#endif
data->yMax = MSG_LINES - 1;
data->yPos = min(data->yPos, data->yMax);
ZeroMemory(&si, sizeof(si));
si.cbSize = sizeof(si);
si.fMask = SIF_RANGE | SIF_PAGE | SIF_POS;
si.nMin = MSG_VISIBLE_LINES;
si.nMax = data->yMax + MSG_VISIBLE_LINES - 1;
si.nPage = MSG_VISIBLE_LINES;
si.nPos = data->yPos;
SetScrollInfo(hWnd, SB_VERT, &si, TRUE);
}
} break;
default:
return DefWindowProc(hWnd, message, wParam, lParam);
}
return 0;
}
void
onMSNHCommand(HWND hWnd, WPARAM wParam, LPARAM lParam)
{
PNHMessageWindow data;
data = (PNHMessageWindow) GetWindowLong(hWnd, GWL_USERDATA);
switch (wParam) {
case MSNH_MSG_PUTSTR: {
PMSNHMsgPutstr msg_data = (PMSNHMsgPutstr) lParam;
SCROLLINFO si;
char *p;
if (msg_data->append) {
strncat(data->window_text[MSG_LINES - 1].text, msg_data->text,
MAXWINDOWTEXT
- strlen(data->window_text[MSG_LINES - 1].text));
} else {
/* check if the string is empty */
for (p = data->window_text[MSG_LINES - 1].text; *p && isspace(*p);
p++)
;
if (*p) {
/* last string is not empty - scroll up */
memmove(&data->window_text[0], &data->window_text[1],
(MSG_LINES - 1) * sizeof(data->window_text[0]));
}
/* append new text to the end of the array */
data->window_text[MSG_LINES - 1].attr = msg_data->attr;
strncpy(data->window_text[MSG_LINES - 1].text, msg_data->text,
MAXWINDOWTEXT);
}
/* reset V-scroll position to display new text */
data->yPos = data->yMax;
ZeroMemory(&si, sizeof(si));
si.cbSize = sizeof(si);
si.fMask = SIF_POS;
si.nPos = data->yPos;
SetScrollInfo(hWnd, SB_VERT, &si, TRUE);
/* deal with overflows */
data->lines_last_turn++;
if (!data->dont_care && data->lines_last_turn >= MSG_LINES - 2) {
char c;
BOOL done;
/* append "--More--" to the message window text (cannot call
putstr
here - infinite recursion) */
memmove(&data->window_text[0], &data->window_text[1],
(MSG_LINES - 1) * sizeof(data->window_text[0]));
data->window_text[MSG_LINES - 1].attr = ATR_NONE;
strncpy(data->window_text[MSG_LINES - 1].text, "--More--",
MAXWINDOWTEXT);
/* update window content */
InvalidateRect(hWnd, NULL, TRUE);
#if defined(WIN_CE_SMARTPHONE)
NHSPhoneSetKeypadFromString("\033- <>");
#endif
done = FALSE;
while (!done) {
int x, y, mod;
c = mswin_nh_poskey(&x, &y, &mod);
switch (c) {
/* ESC indicates that we can safely discard any further
* messages during this turn */
case '\033':
data->dont_care = 1;
done = TRUE;
break;
case '<':
SendMessage(hWnd, WM_VSCROLL, MAKEWPARAM(SB_LINEUP, 0),
(LPARAM) NULL);
break;
case '>':
SendMessage(hWnd, WM_VSCROLL, MAKEWPARAM(SB_LINEDOWN, 0),
(LPARAM) NULL);
break;
/* continue scrolling on any key */
default:
data->lines_last_turn = 0;
done = TRUE;
break;
}
}
#if defined(WIN_CE_SMARTPHONE)
NHSPhoneSetKeypadDefault();
#endif
/* remove "--More--" from the message window text */
data->window_text[MSG_LINES - 1].attr = ATR_NONE;
strncpy(data->window_text[MSG_LINES - 1].text, " ",
MAXWINDOWTEXT);
}
/* update window content */
InvalidateRect(hWnd, NULL, TRUE);
#ifdef USER_SOUNDS
play_sound_for_message(msg_data->text);
#endif
} break;
case MSNH_MSG_CLEAR_WINDOW:
data->lines_last_turn = 0;
data->dont_care = 0;
break;
}
}
void
onMSNH_VScroll(HWND hWnd, WPARAM wParam, LPARAM lParam)
{
PNHMessageWindow data;
SCROLLINFO si;
int yInc;
/* get window data */
data = (PNHMessageWindow) GetWindowLong(hWnd, GWL_USERDATA);
ZeroMemory(&si, sizeof(si));
si.cbSize = sizeof(si);
si.fMask = SIF_PAGE | SIF_POS;
GetScrollInfo(hWnd, SB_VERT, &si);
switch (LOWORD(wParam)) {
// User clicked the shaft above the scroll box.
case SB_PAGEUP:
yInc = -(int) si.nPage;
break;
// User clicked the shaft below the scroll box.
case SB_PAGEDOWN:
yInc = si.nPage;
break;
// User clicked the top arrow.
case SB_LINEUP:
yInc = -1;
break;
// User clicked the bottom arrow.
case SB_LINEDOWN:
yInc = 1;
break;
// User dragged the scroll box.
case SB_THUMBTRACK:
yInc = HIWORD(wParam) - data->yPos;
break;
default:
yInc = 0;
}
// If applying the vertical scrolling increment does not
// take the scrolling position out of the scrolling range,
// increment the scrolling position, adjust the position
// of the scroll box, and update the window. UpdateWindow
// sends the WM_PAINT message.
if (yInc = max(MSG_VISIBLE_LINES - data->yPos,
min(yInc, data->yMax - data->yPos))) {
data->yPos += yInc;
/* ScrollWindowEx(hWnd, 0, -data->yChar * yInc,
(CONST RECT *) NULL, (CONST RECT *) NULL,
(HRGN) NULL, (LPRECT) NULL, SW_INVALIDATE | SW_ERASE);
*/
InvalidateRect(hWnd, NULL, TRUE);
ZeroMemory(&si, sizeof(si));
si.cbSize = sizeof(si);
si.fMask = SIF_POS;
si.nPos = data->yPos;
SetScrollInfo(hWnd, SB_VERT, &si, TRUE);
UpdateWindow(hWnd);
}
}
#ifndef MSG_WRAP_TEXT
void
onMSNH_HScroll(HWND hWnd, WPARAM wParam, LPARAM lParam)
{
PNHMessageWindow data;
SCROLLINFO si;
int xInc;
/* get window data */
data = (PNHMessageWindow) GetWindowLong(hWnd, GWL_USERDATA);
ZeroMemory(&si, sizeof(si));
si.cbSize = sizeof(si);
si.fMask = SIF_PAGE;
GetScrollInfo(hWnd, SB_HORZ, &si);
switch (LOWORD(wParam)) {
// User clicked shaft left of the scroll box.
case SB_PAGEUP:
xInc = -(int) si.nPage;
break;
// User clicked shaft right of the scroll box.
case SB_PAGEDOWN:
xInc = si.nPage;
break;
// User clicked the left arrow.
case SB_LINEUP:
xInc = -1;
break;
// User clicked the right arrow.
case SB_LINEDOWN:
xInc = 1;
break;
// User dragged the scroll box.
case SB_THUMBTRACK:
xInc = HIWORD(wParam) - data->xPos;
break;
default:
xInc = 0;
}
// If applying the horizontal scrolling increment does not
// take the scrolling position out of the scrolling range,
// increment the scrolling position, adjust the position
// of the scroll box, and update the window.
if (xInc = max(-data->xPos, min(xInc, data->xMax - data->xPos))) {
data->xPos += xInc;
ScrollWindowEx(hWnd, -data->xChar * xInc, 0, (CONST RECT *) NULL,
(CONST RECT *) NULL, (HRGN) NULL, (LPRECT) NULL,
SW_INVALIDATE | SW_ERASE);
ZeroMemory(&si, sizeof(si));
si.cbSize = sizeof(si);
si.fMask = SIF_POS;
si.nPos = data->xPos;
SetScrollInfo(hWnd, SB_HORZ, &si, TRUE);
UpdateWindow(hWnd);
}
}
#endif // MSG_WRAP_TEXT
COLORREF
setMsgTextColor(HDC hdc, int gray)
{
COLORREF fg, color1, color2;
if (gray) {
color1 = mswin_get_color(NHW_MESSAGE, MSWIN_COLOR_BG);
color2 = mswin_get_color(NHW_MESSAGE, MSWIN_COLOR_FG);
/* Make a "gray" color by taking the average of the individual R,G,B
components of two colors. Thanks to Jonathan del Strother */
fg = RGB((GetRValue(color1) + GetRValue(color2)) / 2,
(GetGValue(color1) + GetGValue(color2)) / 2,
(GetBValue(color1) + GetBValue(color2)) / 2);
} else {
fg = mswin_get_color(NHW_MESSAGE, MSWIN_COLOR_FG);
}
return SetTextColor(hdc, fg);
}
void
onPaint(HWND hWnd)
{
PAINTSTRUCT ps;
HDC hdc;
PNHMessageWindow data;
RECT client_rt, draw_rt;
int FirstLine, LastLine;
int i, x, y;
HGDIOBJ oldFont;
TCHAR wbuf[MAXWINDOWTEXT + 2];
size_t wlen;
COLORREF OldBg, OldFg;
hdc = BeginPaint(hWnd, &ps);
OldBg = SetBkColor(hdc, mswin_get_color(NHW_MESSAGE, MSWIN_COLOR_BG));
OldFg = setMsgTextColor(hdc, 0);
data = (PNHMessageWindow) GetWindowLong(hWnd, GWL_USERDATA);
GetClientRect(hWnd, &client_rt);
if (!IsRectEmpty(&ps.rcPaint)) {
FirstLine = max(
0, data->yPos - (client_rt.bottom - ps.rcPaint.top) / data->yChar
+ 1);
LastLine =
min(MSG_LINES - 1,
data->yPos
- (client_rt.bottom - ps.rcPaint.bottom) / data->yChar);
y = min(ps.rcPaint.bottom, client_rt.bottom - 2);
for (i = LastLine; i >= FirstLine; i--) {
if (i == MSG_LINES - 1) {
x = data->xChar * (2 - data->xPos);
} else {
x = data->xChar * (4 - data->xPos);
}
if (strlen(data->window_text[i].text) > 0) {
/* convert to UNICODE */
NH_A2W(data->window_text[i].text, wbuf, sizeof(wbuf));
wlen = _tcslen(wbuf);
/* calculate text height */
draw_rt.left = x;
draw_rt.right = client_rt.right;
draw_rt.top = y - data->yChar;
draw_rt.bottom = y;
oldFont = SelectObject(
hdc,
mswin_get_font(NHW_MESSAGE, data->window_text[i].attr,
hdc, FALSE));
setMsgTextColor(hdc, i < (MSG_LINES - data->lines_last_turn));
#ifdef MSG_WRAP_TEXT
DrawText(hdc, wbuf, wlen, &draw_rt,
DT_NOPREFIX | DT_WORDBREAK | DT_CALCRECT);
draw_rt.top = y - (draw_rt.bottom - draw_rt.top);
draw_rt.bottom = y;
DrawText(hdc, wbuf, wlen, &draw_rt,
DT_NOPREFIX | DT_WORDBREAK);
#else
DrawText(hdc, wbuf, wlen, &draw_rt, DT_NOPREFIX);
#endif
SelectObject(hdc, oldFont);
y -= draw_rt.bottom - draw_rt.top;
} else {
y -= data->yChar;
}
}
}
SetTextColor(hdc, OldFg);
SetBkColor(hdc, OldBg);
EndPaint(hWnd, &ps);
}
void
onCreate(HWND hWnd, WPARAM wParam, LPARAM lParam)
{
HDC hdc;
TEXTMETRIC tm;
PNHMessageWindow data;
HGDIOBJ saveFont;
/* set window data */
data = (PNHMessageWindow) malloc(sizeof(NHMessageWindow));
if (!data)
panic("out of memory");
ZeroMemory(data, sizeof(NHMessageWindow));
data->max_text = MAXWINDOWTEXT;
SetWindowLong(hWnd, GWL_USERDATA, (LONG) data);
/* Get the handle to the client area's device context. */
hdc = GetDC(hWnd);
saveFont =
SelectObject(hdc, mswin_get_font(NHW_MESSAGE, ATR_NONE, hdc, FALSE));
/* Extract font dimensions from the text metrics. */
GetTextMetrics(hdc, &tm);
data->xChar = tm.tmAveCharWidth;
data->xUpper = (tm.tmPitchAndFamily & 1 ? 3 : 2) * data->xChar / 2;
data->yChar = tm.tmHeight + tm.tmExternalLeading;
data->xPage = 1;
/* Free the device context. */
SelectObject(hdc, saveFont);
ReleaseDC(hWnd, hdc);
/* create command pad (keyboard emulator) */
if (!GetNHApp()->hCmdWnd)
GetNHApp()->hCmdWnd = mswin_init_command_window();
}
void
mswin_message_window_size(HWND hWnd, LPSIZE sz)
{
PNHMessageWindow data;
RECT rt, client_rt;
GetWindowRect(hWnd, &rt);
sz->cx = rt.right - rt.left;
sz->cy = rt.bottom - rt.top;
data = (PNHMessageWindow) GetWindowLong(hWnd, GWL_USERDATA);
if (data) {
/* set size to accomodate MSG_VISIBLE_LINES, highligh rectangle and
horizontal scroll bar (difference between window rect and client
rect */
GetClientRect(hWnd, &client_rt);
sz->cy = sz->cy - (client_rt.bottom - client_rt.top)
+ data->yChar * MSG_VISIBLE_LINES + 4;
}
}
| 2023-09-15T01:26:59.872264 | https://example.com/article/3606 |
Truck Size & Weight
Small business truckers oppose efforts by major motor carriers and shippers to increase truck size and weight limits. Not only are there significant infrastructure and safety concerns with bigger and heavier trucks, but increases will shift costs like fuel, equipment, and insurance onto small business carriers.
Higher Costs for Small Businesses.
Higher limits will lead to higher operating and equipment costs for small business truckers. It is important to note that any size or weight ceiling soon becomes the de facto standard, forcing truckers to upgrade to remain competitive. While large fleets can absorb these increased costs or segment out a portion of their fleet to serve heavier loads, small business truckers lack that luxury. Increased costs include:
Purchasing new trailers to handle heavier weights if existing trailers cannot be upgraded. Cost will range close to $100,000 for two new trailers.
Fuel costs rise due to heavier weight. Shippers unlikely to increase compensation to cover these additional costs. Costs also rise when the truck hauls less than 97,000 lb. loads due to added weight of equipment.
Truckers must pay greater insurance premiums, more expensive repair bills, and will see their truck equipment, especially safety-critical equipment like brakes and tires, deteriorate at a faster rate. More repairs mean more down-time for the truck, pulling the small trucker off the road and from making money.
Past TSW increases have served as a reason to increase taxes and fees on all trucks, including those not operating at the new limits, and with no guarantee that the funds would be directed at improving highways. No shipper is going to feel the burden of these new costs.
Increasing Safety Challenges.
OOIDA’s members have an average of more than two decades behind the wheel and two million miles driven without a DOT reportable accident. They know that the increased weight and greater length of these vehicles results in a direct negative impact on vehicle stability, mobility, and maneuverability due to real-world operating experience – actual loads, real traffic, bad weather, poor road conditions, and steep grades.
The 6th-axle on a 97,000 lb. truck adds weight and does not solve braking problems.
Driving a heavier vehicle increases stress and impacts how the vehicle behaves around other vehicles.
There is no requirement for entry-level drivers to complete behind-the-wheel training.
Greater Infrastructure Damage.
Increasing truck size and weight limits would accelerate the deterioration of the nation's highways and bridges and increase our nation’s infrastructure deficit.
In addition to the amplified damage to roadways and bridges, the 6th axle boosts the damage to road surfaces related to “scuffing” - where the vehicle’s tires drag across the road surface when turning. This is especially common on local roads and streets when vehicles turn in and out of factories, warehouses, and truck stops.
As the size and weight of vehicles increase, the number of highways and bridges that are able to accommodate them become fewer. Factories and other locations could be cut off from truck transportation due to bridge weight limits or intersections unable to handle wider turning angles of LCVs.
The already existing truck parking shortage would only get worse as LCVs take up more parking spaces. | 2024-07-23T01:26:59.872264 | https://example.com/article/5583 |
---
abstract: |
New dielectric transitions are observed at common temperatures $32K$ and $%
245K,$ in isostructural $La_{2}CuO_{4+x}$ and $La_{5/3}Sr_{1/3}NiO_{4},$that are signatures of local lattice (octahedral) instabilities. The present dielectric transitions reveal new aspects of the phase diagram of the perovskite cuprates and nickelates. They suggest that competition and coexistence of superconductivity with dielectricity occurs that is analogous to that between superconductivity and anti-ferromagnetism. These results also indicate that inhomogeneous electronic states, such as charge stripes and oxygen ordering, are strongly connected to underlying lattice instabilities.
address: |
$^{1}$Physics Department, Northeastern University, 360 Huntington Avenue, Boston, MA 02115\
$^{2}$Center for Material Science and Engineering, MIT, Cambridge, MA 02139\
$^{3}$Physics Department, Rutgers University, Piscataway, NJ 08854
author:
- 'P. V. Parimi$^{1}$, N. Hakim$^{1}$, F. C. Chou$^{2}$, S. W. Cheong$^{3}$ and S. Sridhar$^{1}$'
title: |
Dielectric signatures of lattice instabilities at $32K$ and $245K$ in $%
La_{2-y}Sr_{y}MO_{4+x}$ ($M=Cu,Ni$) Cuprates and Nickelates
---
[2]{} The presence of intrinsic electronic inhomogeneities in $%
La_{2-y}Sr_{y}MO_{4}:M=Cu,Ni$ ($LSMO)$ is now becoming widely recognized [@kastner98; @xiong96; @tranquada95; @hammel90; @hundley90]. Static stripe phases have been observed in $La_{2-y}(Nd,Sr)_{y}CuO_{4}$ [@tranquada95], and in $La_{2-y}Sr_{y}NiO_{4}$ [@lee97] with onset around $245K$. Mechanisms suggested have been purely Coulombic (electron-electron) or magnetic in nature with a strictly 2D planar picture ignoring the involvement of lattice. In the $La_{2-y}Sr_{y}CuO_{4}$ and $%
La_{2-y}Ba_{y}CuO_{4}$ the global lattice transitions, such as LTO, Pccn, and LTT are well known to be associated with the tilts of the octahedra [@jorgensen92]. Phase separation into oxygen rich ($x>0$) and poor ($x=0$) regions around $245(\pm 5)K$ and miscibility gap have been observed [@tranquada; @toru95; @reyes93; @kremer92; @ishihara00], leading to the coexistence of both superconductivity and antiferromagnetism in the phase separated regions, and formation of intercalated oxygen layers with staging. Significant jumps are seen in thermal expansion at $T_{c}$ in various HTS[@meingast91; @lang92]. A correlation is observed between the lattice modes and electronic susceptibiltiy in $La_{2-y}Sr_{y}CuO_{4}$[@mcqueeney01]. These results urge investigation of lattice-charge coupling and the resultant lattice-charge phase diagram similar to purely magnetic and structural phase diagrams that have been obtained from spin and lattice probes[@kastner98; @jorgensen92].
In this Letter we report the observation of new dielectric transitions at common temperatures $32K$ and $245K,$ in $La_{2}CuO_{4+x}$ and $%
La_{5/3}Sr_{1/3}NiO_{4},$ that are signatures of local lattice (octahedra) instabilities. The present results, which reveal a striking commonality of the perovskite cuprates and nickelates, connect a series of other measurements indicating anomalies in the vicinity of $32K$ and $245K$. This connection is made here for the first time, and reveals new aspects of the phase diagram of these isostructural oxides not recognized before. These results suggest that inhomogeneous electronic states such as charge stripes and oxygen ordering are strongly connected to the underlying lattice instabilities rather than arising from purely magnetic or electronic interactions.
A number of conventional local probes have been used to investigate structural instabilities such as XAFS, NMR, NQR, Neutron diffraction and Mossbauer spectroscopies. These techniques are powerful local probes[@egami; @mihai93], however, their sensitivity is limited for probing small displacements of atoms from centrosymmetric structures. The present work utilizes precision dielectric measurements, carried out using a highly sensitive superconducting (Nb) microwave cavity, which reveal signatures of subtle structural instabilities. The very high quality factor, $Q\simeq
10^{8},$ of the cavity makes this technique a powerful tool to investigate small displacements of atoms from centrosymmetric structure especially in non-magnetic insulators, where the polarization response dominates the spin response due to the high frequency, as has been evidenced by strong dielectric transitions in $YBa_{2}Cu_{3}O_{7-\delta }$[@zhai01].
High quality single crystals of $La_{2}CuO_{4+x}$ $(x=0.0125,0.0175)$[@blakeslee] and $La_{5/3}Sr_{1/3}NiO_{4}$[@lee97] were prepared by the TSFZ method and have been well characterized by a variety of other techniques. The excess $O$ concentration, $x$ in $La_{2}CuO_{4+x}$, was determined from dc magnetic SQUID susceptibility measurements and well-established relation between the Neel temperature $T_{N}$ and $x$. The sample is placed at the maximum of the microwave magnetic field $H_{\omega }$ of the $TE_{011}$ mode resonant at $10GHz$. The dielectric permittivity $%
\widetilde{\varepsilon }(T)=\varepsilon ^{\prime }(T)+i\varepsilon ^{\prime
\prime }(T)$ is determined from the measured parameters, shift in cavity resonant frequency $\delta f(T)$ and resonance width $\Delta f(T)$[@zhai00]. In all the measurements $\widetilde{\varepsilon }(T)$ is monitored as the sample is warmed slowly at the rate of 1.3K/min.
The microwave dielectric permittivity $\widetilde{\varepsilon }_{a}(T)$ when the microwave magnetic field $H_{\omega }\,\parallel a-axis$ of $%
La_{2}CuO_{4.0175}$ shows a clear transition at $32K$ and two additional features whose onset is at $100K$ and $245K$ (Fig. 1). Below these transition temperatures the change in $\varepsilon ^{\prime }(T)$ is accompanied by loss peaks in $\varepsilon ^{\prime \prime }(T)$. The $32K$ transition is marked by a rapid increase in both $\varepsilon ^{\prime }(T)$ and $\varepsilon ^{\prime \prime }(T)$ as the temperature is decreased and is strongly thermal history dependent. This transition is found to be dependent on the cooling rate and annealing time at maximum temperature, $%
294K$ suggesting a glassy nature. A very strong transition is observed in $%
\widetilde{\varepsilon }(T)$ when the sample had been slowly cooled down from $294K$ to $4K$ in about $16$ hours. However, rapid cooling of the sample from 294K to 4K in 2hrs and subsequent measurement of $\widetilde{%
\varepsilon }(T)$ results in a weak transition. The strength of the transition is dependent upon the previous maximum warm-up temperature $%
T_{max}$- thus this transition has features of thermal aging that are often characteristic of dielectric transitions. An additional feature has been observed at low $T=17K$, which is associated with incipient superconductivity in micro domains as indicated by dc SQUID magnetization measurement. This transition is suppressed when the sample is cooled rapidly.
Remarkably, $La_{5/3}Sr_{1/3}NiO_{4}$ also shows two dielectric transitions for $H_{\omega }\,\parallel \,a$ in $\widetilde{\varepsilon }(T)$ at $32K$ and $245K$ as shown in Fig. 2. As in the case of $La_{2}CuO_{4.0175}$ the $%
32K$ transition in $La_{5/3}Sr_{1/3}NiO_{4}$ is suppressed when the sample is quenched, indicating thermal aging, while the remainder of the data is less sensitive to thermal history. It was also observed that the $32K$ transition is unaffected when the sample was annealed at and above 200K for several hours. This indicates that the phase formed between $200K$ and room temperature appears to be crucial in giving rise to the $32K$ transition.
The present data can be analyzed in terms of multiple dielectric modes, $%
\tilde{\varepsilon}(T)=\tilde{\varepsilon}_{\alpha }(T)+\tilde{\varepsilon}%
_{\beta }(T)+\tilde{\varepsilon}_{\gamma }(T)+...$, each of which is well described by a Debye relaxation form with respect to the temperature dependence
$$\tilde{\varepsilon}(T)=\tilde{\varepsilon}_{\alpha }+\tilde{\varepsilon}%
_{\beta }+...=\sum_{i=\alpha ,\beta ,\gamma ,..}\frac{\varepsilon _{i0}(T)}{%
1-i\omega \tau _{i}(T)},$$
where $\varepsilon _{i0}(T)$ are static dielectric functions and $\tau
_{i}(T)$ relaxation times for each mode.
In $La_{2}CuO_{4.0175}$ three contributions can be identified. $\tilde{%
\varepsilon}_{\alpha }(T)$ indicates the onset of a new dielectric mode which turns on below 32K. We describe this mode with parameters $\varepsilon
_{\alpha 0}(T)=900(1-T/T_{d\alpha })$ with $T_{d\alpha }=32K$ and $\tau
_{\alpha }(T)=6.5\times 10^{-9}(\sec \cdot K)/T$. $\varepsilon _{\alpha
0}(T) $ is similar to an order parameter which grows below a transition. As $%
T$ is lowered, $\tilde{\varepsilon}_{\alpha }(T)$ increases initially due to gradual displacement of Oxygen from centrosymmetric position leading to growing polarization as described in the octahedra model latter. However below a characteristic temperature $\tilde{\varepsilon}_{\alpha }(T)$ begins to decrease because the dipoles are no longer able to follow the microwave field. In $La_{5/3}Sr_{1/3}NiO_{4}$ the $32K$ dielectric mode has a much weaker strength with $\varepsilon _{\alpha 0}(T)\sim 0.5(1-T/T_{d\alpha })$, and requires a highly sensitivity measurement such as the present microwave measurement. $\tilde{\varepsilon}_{\beta }(T)$ of $La_{2}CuO_{4.0175}$ associated with $T_{d\beta }=245K$ transition is described by $\varepsilon
_{\beta 0}(T)=10(1-T/T_{d\beta })$ with and $\tau _{\beta }(T)=1\times
10^{-9}(\sec \cdot K)/T.$ $\tilde{\varepsilon}_{\gamma }$(T) which is dominant at higher T is described with a relaxation time $\tau _{\gamma
}(T)=8\times 10^{-13}\sec ^{-1}\exp (1000/T)$ characterized by an activation energy $1000K$.
The present transitions are strikingly similar to the microwave dielectric transitions at $60K$ and $110K$ observed in insulating $YBa_{2}Cu_{3}O_{6.0}$[@zhai01], whose dielectric permittivity is also well described by eqn. (1). These transitions were identified with lattice instabilities - change in buckling angle for 110K transition - that have been observed in many measurements, including ion channeling[@sharma00].
It is important to stress that all these materials are $ABO_{3}$ type perovskites, which are well known to show strong dielectricity, notable examples being the ferroelectric $BaTiO_{3}$ and the quantum paraelectric $%
SrTiO_{3}$. The perovskites readily display a variety of competing structural instabilities that lead to different ferroelectric states [@muller]. In these materials it is well established that the dielectricity (ferroelectricity) ensues from the strong polarizability of oxygen ion in the presence of cations ($Ba,La,Sr,Ti,Cu.....$) and that the relevant dynamical and critical features are controlled by a limited number of parameters such as the effective coupling between the cation ($Ti,Cu$) and $%
O $. The presence of dipolar modes in $YBa_{2}Cu_{3}O_{7-\delta }$ arising from coupling of the buckled $Cu-O$ planes with electric-diploe $Ba-O$ layers has been theoretically addressed by Shenoy, et al.[@Shenoy97].
The surprising commonality of the dielectric transitions in both $%
La_{2}CuO_{4.0175}$ and $La_{5/3}Sr_{1/3}NiO_{4}$ strongly suggests contributions from a common unit with a characteristic energy scale that in these isostructural units is the $MO_{6}$ octahedron. Such a description finds strong theoretical support from the work by Thomas[@noel90] where it was shown that the dielectric response of $ABO_{3}$ type perovskites was describable in terms of individual $BO_{6}$ octahedra. The dielectric function of the present crystals is high and could arise from an induced dipole moment extended over a cation-anion bond distance, in this case $M-O$ bond distance. Electron covalency between a cation and anion induces a large dipole moment[@noel90; @ishihara94] which originates from the charge transfer between the anion and cation sites. In the $La_{2}MO_{4+x}$ and $%
La_{2-y}Sr_{y}MO_{4}$ the $MO_{6}$ octahedra are further coupled both electronically and vibrationally, and form arrays of weakly coupled rigid units. There are a certain number of very low frequency vibrational modes (or rigid unit modes, RUMs ) of these units which do not distort the units but flex the coupling between them. These RUMs are natural candidates for the soft modes that typically drive displacive dielectric phase transitions[@giddy93]. Since the large inter layer strains between the $MO_{2}$ and $LaO$ planes[@goodenough90] can be relieved by tilting of the $MO_{6}$ octahedra or correlated ferrodistortive buckling of $MO_{2}$ plane with displacement of $O$ atoms in the plane we attribute the $32K$ and $245K$ transitions to the onset of such a long wavelength, near- ferrodistortive distortion. These displacements would result in a change in bond lengths and thereby a change in effective $\tilde{\varepsilon}(T)$.
The suppression of $\varepsilon _{\alpha }(T)$ in the quenched samples of $%
La_{2}CuO_{4.0175}$ and $La_{5/3}Sr_{1/3}NiO_{4}$ is a manifestation of competition between order and disorder. In the well annealed, slow cooled $%
La_{2}CuO_{4.0175}$ the excess oxygen forms intercalated layers as shown in Fig. 3a and in $La_{5/3}Sr_{1/3}NiO_{4}$ the holes form charge ordered stripes. However, rapid cooling does not result in ordering but highly disordered oxygen as shown in Fig 3b. An intercalated oxygen atom dispalces the apical oxygens and thereby leads to the distortion and tilt of the octahedra. In the ordered state the majority of octahedra chains are unperturbed by the excess-oxygen which leads to a strong transition. However in the disordered state since the excess O are randomly distributed above or below the octahedra plane as interstitial impurities they will have a bearing on the entire plane. Consequently in the Debye model for the disordered state $\tilde{\varepsilon}_{\alpha }(T)$ is well described by $%
\varepsilon _{\alpha 0}(T)=100(1-(T/T_{d\alpha })$ (solid line Fig.1) with $%
\tau _{\alpha }(T)$ being same as that of the ordered state for this mode. The role of disorder in suppressing the $32K$ transition is evidenced in the measurement on flux grown crystals of $La_{2}CuO_{4}$ (not shown) where our $%
10GHz$ dielectric data shows suppression of the $32K$ transition, consistent with earlier dielectric measurements [@reagor; @kastner98].
In the case of $La_{5/3}Sr_{1/3}NiO_{4}$ suppression of $\varepsilon
_{\alpha }(T)$ indicates that high temperature ( $>$ $245K$ ) annealing determines the strength of transition at $32K$. We further argue that charge ordering per se has a driving lattice component in it because purely electronic states are not expected to be dependent on thermal annealing. We believe that quench disorder (rapid cooling) would lead to a change in the structure of charge stripe formation which would affect the tilts of octahedra at $32K$ resulting in a weak dielectric transition.
Another temperature scale that is common to $La_{2}CuO_{4+x}$ and $%
La_{5/3}Sr_{1/3}NiO_{4}$ is around $245K$ (see Figs.1 & 2). The $245K$ transition in $\widetilde{\varepsilon }(T)$ of $La_{2}CuO_{4+x}$ is attributed to oxygen ordering observed in neutron diffraction measurements by Tranquada, et. al.[@tranquada]. In $La_{2-x}Sr_{x}NiO_{4}$, a detailed elastic neutron diffraction study has demonstrated charge ordering around $T_{cCO}=245K$ into domain walls or stripes[@lee97]. In the dielectric response this leads to the onset of a dielectric mode associated with the stripe formation (see Fig.2). In both these materials we can associate a dielectric mode $\tilde{\varepsilon}_{\beta }(\omega ,T)$ with the $245K$ feature. That Oxygen ordering and charge ordering take place at the same temperature in $LCO$ and $LSNO$ is now understandable since it is the underlying lattice instability, observed here as a dielectric transition at $245K$, that drives these transitions in these two isostructural compounds.
Observation of the $32K$ dielectric transition and its relation to the $%
MO_{6}$ octahedra modes also explains the origin of anomalies at this temperature in NQR, thermal expansion and specific heat. Thermal expansion measurements [@lang92] reveal changes at $32K$ and $36K$ in the coefficient of thermal expansion indicating lattice changes. Migliori et al.[@migliori90] have observed a feature with onset at $32K$ in the specific heat of $La_{2}CuO_{4}$. NQR measurements [@brom00] reveal a change in the $^{139}$La spin-lattice relaxation rate and spin-spin dephasing rate between $30K$ and $38K$ [@brom00]. Anelastic measurements revealed softening of $La_{2}CuO_{4}$ lattice with onset around $32K$[@cordero98]. Recently, Takao, et. al.[@wakimoto00] observed a change in sound velocity at $36K$ in $La_{2}CuO_{4.05}$ which is found to be present even after suppression of superconductivity by magnetic field. While all these measurements indicate a structural change at $32K$ (and 36K) our microwave dielectric measurements connect these changes to the instability of the octahedra. The $MO_{6}$ octahedron is strongly coupled to the $La$ nuclear moment through an orbital hybridization mediated by apical oxygen [@yoshinari98]. Therefore, the subtle tilt/distortion of the octahedra directly affects the $^{139}$La spin-lattice relaxation rate. Thus our microwave measurements indicate that dipolar-phonon mediated mechanisms are important and play a significant role in inducing many electronic transitions in these materials.
The coexistence of , and competition between dielectricity and superconductivity is clearly evident in the result obtained on a single crystal $La_{2}CuO_{4}._{0125},$ for $H_{mw}\parallel a$ a dielectric transition is observed at $31K$ followed by onset of superconductivity at $%
27K$ (inset Fig. 1b). This observation coupled with the results on $x=0.0175$ crystal (Fig. 1) suggests that the dielectric and superconducting transitions are independent of each other, and when the crystal superconducts the dielectric response is overshadowed below $T_{c}$. Its important to note that the competition between ferroelectricity and superconductivity is well-known in the A-15 compounds, and its possible relevance to perovskite oxides was noted shortly after the discovery of high temperature superconductivity [@Muller].
The importance of the present results is emphasized in a new phase diagram (Fig. 4) constructed from the present microwave observations and other results reported earlier on $LMO$ and $LSMO$, which together reveal unambiguously new structural instabilities at $32K$ and $245(\pm 5)K$. The structural instability at $245(\pm 5)K$ leads to charge ordering in the case of $LSNO$ and oxygen ordering in the case of $LCO$. The fact that these compositions have different hole doping suggests that these transitions are purely structure dependent and almost independent of hole doping in the low doping regime. In contrast the magnetic ($T_{N}$) and superconducting transitions ($T_{c}$) are well-known to be doping dependent. It is important to note a striking similarity of the present transitions in $LSCO$ and $LSNO$ to multiple temperature scales observed in ion channeling measurements on $%
YBa_{2}Cu_{3}O_{7-\delta }$ [@sharma00]. The present observation of signatures of octahedra instability at common temperatures in both underdoped (no stripes) and doped (presence of stripes) regimes confirms that charge stripes and oxygen ordering are coupled to the underlying lattice instabilities rather than resulting purely from magnetic or electronic interactions. There are a few other temperatures where lattice anomalies were reported previously [@lang92]. However, not all the lattice instabilities would effect the octahedra (RUMs) and correspondingly have dielectric signatures. In the phase diagram we emphasized only those results that show anomalies at $32K$ and $245K$ and are related to the present dielectric transitions. The present dielectric transitions at common temperatures underscore the importance of subtle local structural instabilities that result in dramatic changes in the electronic properties of perovskite oxides.
We thank R. S. Markiewicz and S. R. Shenoy for enlightening discussions. This work was supported at Northeastern by the ONR and NSF, and at MIT by NSF-DMR-9808941.
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