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8d28ce14-92bb-4576-9223-1a6e709a8dc7 | Tissue f r om rat used for detection of antinuclear antibodies | Kidney | Brain | Stomach | Liver | 3d | single | Serum antinuclear antibodies bind to corresponding antigents present in the rat liver section.the antigen-antibody complexes are detected by means of fluorescent labeled anti human immunoglbulin .and visualised with the aid of a fluorescence microscopy ref Robbins 9/e immunity chapter p131 and internet | Anatomy | General anatomy |
933df2f9-ed46-467e-9844-911b590fbddb | A woman delivers a 91b infant with a midline episiotomy and suffers a third degree tear. Inspection shows which of the following structures is intact : | Anal sphincter | Perineal body | Parineal muscles | Rectal mucosa | 3d | single | Rectal mucosa | Gynaecology & Obstetrics | null |
04e0a0a9-08b6-4c0e-b034-6fb11de975a4 | Most common cause of CTEV DEFORMITY IS ? | Ahrogryposis multiplex congenita | Spina bifida | Idiopathic | Neural tube defect | 2c | single | Aeitiology of CTEV can be - *idiopathic(majority)some of the theories proposed to the aetiology of idiopathic clubfoot : a)Mechanical theory - raised intrauterine pressure forces the foot against the wall of the uterus in position of the deformity b)ischaemic theory - ischemia of the calf muscles during intrauterine li... | Orthopaedics | Pediatric orthopedics |
65bb604d-f85f-4302-b6f4-e180fedb0805 | Which of the following cannot be done by a 3 year old child? | Draw a circle | Draw a rectangle | Telling a story | Riding tricycle | 1b | single | A child can draw a rectangle by the age of 4 years. All other options can be performed by a 3 year old child. Ref: O P Ghai, 7th Edition, Pages 26-29, 6th Edition, Page 44; Nelson, 18th Edition, Page 44. | Pediatrics | null |
a1e3fbde-5d2b-4147-961c-0cfdc5844860 | During autopsy of suspected anaesthetic poisoning,lung excised from hilum is to be preserved in ? | PVC container | Metal container | Nylon bag | Poly ethylene bag | 1b | single | Ans. is 'b' i.e., Metal container In normal toxicological examination one lung is preserved in sealed nylon bag. In case of inhaled anesthetic, intact lung with bronchi ligated should be kept in gas sealed metal/ non plastic containers of appropriate size to avoid empty space and are sealed and refrigerated/ frozen. Al... | Forensic Medicine | null |
b393abb9-be7c-4b50-916c-1dffd4a5023a | Most commonly lesion associated with pathological fracture in hand is - | Enchondroma | Metastases | Osteoid osteoma | Osteochondroma | 0a | single | Ans. is 'a' i.e., Enchondroma Pathological fractures in hand* In hand pathological fractures are most commonly associated with benign bone tumors.* About 23 % of the bone tumors in hand present with pathological fractures.* The average age of presentation is 37 years.* The most common bone affected is the proximal phal... | Orthopaedics | Bone Tumour |
8aa0fca3-0f40-45fa-8ab4-01c77122c0ca | Phassy jaw is caused by | Yellow phosphorus | White phosphorus | Cadmium | Lead | 1b | single | Phossy Jaw is produced by chronic white phosphorus poisoning. | Forensic Medicine | null |
653e1924-a0e6-4c37-8671-d25d8832c02e | Gastrojejernostomy surgery belongs to | Clean surgery | Contaminated surgery | Clean contaminated surgery | Dirty surgery | 2c | single | Clean contaminated surgery :
Wound is exposed to not only skin but also GI tract / Respiratory tract / Urinary tract organism in controlled enviroment.
Hence Gastrojejunostomy surjery belongs to this category. | Surgery | null |
d97fe4ec-e011-42d5-8221-79c1e39b3cc6 | What is malignant hydatid disease - | Malignant changes into hydatid cyst | Infection with E. multilocularis | Hydatid disease in immunocompromised host | Caused by Echino.granulosus | 1b | single | Echinococcus multilocularis Hydatid disease: Liver is the common organ affected (98% of cases). The disease may resemble a slowly growing carcinomaand may cause symptoms of intrahepatic poal hypeension. Hepatomegaly and hypeension. Cyst appears as solid, film mass with irregular outer layer and has an ability to migrat... | Microbiology | Parasitology Pa 2 (Helminthology) |
4cb7b4a2-46c9-415f-b777-90a917f7a636 | Dumping syndrome is associated with- | Reduction of part of stomach | Decreased gastric secretion | Hyperglycemia | Decreased absorption | 0a | single | Ans. is 'a' i.e., Reduction of part of stomach Dumping syndrome -o Symptom complex that occurs following ingestion of a meel wrhen part of stomach has been removed or the pyloric sphincter mechanism has been disrupted.o Dumping syndrome refers to a constellation of post-prandial symptoms occuring due to accelerated emp... | Surgery | Postgastrectomy Complications |
19a6cc6f-bea5-42fd-b4f3-a83e7c200299 | Treatment resistant hypokalemia is caused by: | Administration of granulocyte colony stimulating factor | Clay ingestion | Barium toxicity | Hypomagnesemia | 3d | single | All the given options are known to cause hypokalemia but with different mechanisms. And only hypomagnesemia is described to cause treatment resistant hypokalemia among the following. Must Know: Systemic hypomagnesemia can cause treatment resistant hypokalemia due to 1. Reduced cellular uptake of potassium 2. Exaggerate... | Medicine | null |
cbb5952f-281c-4f17-846f-81f13b047857 | Treatment of Zollinger Ellison syndrome - | Total gastrectomy with removal of tumour | Partial gastrectomy | Excision of tumour alone | H2, receptor antogonist | 2c | single | • GISTs: MC mesenchymal tumor of the GI tract
• MC primary site for GIST: Stomach (60–70%) > small bowel (20–25%) > colorectum and esophagus (5% each).
• Most GISTs are positive for CD-117 (95%), BCL-2 (80%), CD-34 (70%)
• Types: Spindle cell (70%) and Epitheloid (30%)
Pathology:
• Arise from the muscularis propria and... | Surgery | null |
fab512d1-39cf-4def-8286-bd2676fe1169 | Myositis ossificans is due to: | Ossification | New bone formation | Ossification of subperiosteal haematoma | All of the above | 3d | multi | D i.e. All | Surgery | null |
b7479c46-5457-45fb-90c5-e9b02a9d451a | The following symptoms are common in Anorexia nervosa EXCEPT | Weight loss | Mood changes | Dehydration | Menorrhagia | 3d | multi | (D) Menorrhagia # ANOREXIA NERVOSA:> Eating disorder, commonly in females in adolescence.> Disturbed body image\> Refusal form light calorie food> Weight loss (>25% of body weight)> Amenorrhea (> 3 months)> Absence of other psychiatric disorder> Downy lanugo hair on trunk and limbs> Hypotension, bradycardia, peripheral... | Psychiatry | Miscellaneous |
4743a404-4095-4c48-8ffe-2b567dd527a5 | All of the following lead to increased dissociation of O2 from Hb except | HbF | Increased CO2 | Increase H+ | Increase Temperature | 0a | multi | Fetal hemoglobin or fetal hemoglobin, (also hemoglobin F or HbF) is the main oxygen transpo protein in the human fetus during the last seven months of development in the uterus and in the newborn until roughly 6 months old.Ref: Ganong&;s Review of Medical Physiology; 24th edition; page no:641 | Physiology | Respiratory system |
8443b4e8-d2fa-4841-83fa-d6f438f786a5 | If the same individual participates in both study and experimental group (patient serves as his or her own control), it is called: | Cross over study | Case control study | Cohort study | Experimental study | 0a | multi | Ans. A. Cross over studyExplanationCross over type of study designs are the randomized controlled trials, in which each patient serves as his own control. A better understanding can be taken from the diagram.Here the patient is initially either enrolled into intervention group or control group, after a specified durati... | Social & Preventive Medicine | Epidemiology |
3e753ad3-8e3c-4e41-9a36-bee2ac5f6bdc | Herd immunity provides protection to- | Immunized persons | Non immunized persons | Both | None | 1b | multi | Herd immunity describes a type of immunity that occurs when the vaccination of a poion of the population provides protection to unprotected individuals provides an immunological barrier to the spread of disease in human herd elements-(a) occurence of clinical and sub clinical infection in the herd ( b ) immunization of... | Social & Preventive Medicine | Epidemiology |
82656d9e-881a-4ad2-a868-a0e6438ca1f1 | A number of structural chromosome abnormalities are seen clinically. No loss of genetic material occurs in: | Deletion | Inseion | Substitution | Inversion | 3d | multi | These occur when there are two breaks in the same chromosome, and the intervening genetic material is inveed before the breaks are repaired. Although no genetic material is lost or duplicated, the rearrangement may alter gene function. Ref: Cunningham F.G., Leveno K.J., Bloom S.L., Hauth J.C., Rouse D.J., Spong C.Y. (2... | Biochemistry | null |
bdf0726a-b7be-4f74-a9d8-64e0353c68a9 | Commonest tumour of lumbar region in children is ? | Dermoid cyst | Neuroblastoma | Wilm's tumour | Mesentric cyst | 1b | single | Ans is 'b' ie Neuroblastoma "Neuroblastoma is the most common solid tumor of childhood outside the CNS. It is the most frequently diagnosed neoplasm in infant. The median age at diagnosis is 2 yrs. 90% of cases are diagnosed before the age of 5 yrs. NB may develop at any site of sympathetic nervous system, most NB aris... | Surgery | null |
d2daf97c-ad92-422f-984a-9372b101f30e | Which of the following is not STD | Hepatitis A virus | HPV | HIV | Hepatitis B virus | 0a | single | Hepatitis A virus transmission is by the fecal-oral route. Infection is by ingestion. The virus multiplies in the intestinal epithelium and reaches liver by hematogenous spread. It is shed in the faeces during the late incubation period and prodromal phase of illness. All other options are sexually as well as parentera... | Microbiology | miscellaneous |
7a9e4db6-6173-4fc2-8d5f-daf8061734a3 | A 60 yr old chronic smoker presents with painless gross hematuria of 1 day duration. Which is the investigation of choice to know the cause of hematuria? | USG | X-ray KUB | Urine routine | Urine microscopy for malignant cytology cells | 3d | single | A chronic smoker with painless gross hematuria should be suspected as having bladder cancer. The most common form of bladder cancer is transitional cell carcinoma (TCC). Tobacco use, followed by occupational exposure to various carcinogenic materials such as automobile exhaust or industrial solvents are the most freque... | Surgery | null |
41a09f11-261a-4205-aca3-8a4acb883153 | Which of the following does not cause bradycardia | Propranolol | Hydralazine | Clonidine | Reserpine | 1b | single | Ans. is 'b' i.e., Hydralazine o Hydralazine causes reflex tachycardia. o Propranolol, clonidine and reserpine are sympatholytic drugs cause bradycardia. | Pharmacology | null |
c61ad5a7-549b-4f93-a797-1c33f8a1623c | Half life of Technetium 99 is: | 2 hours | 6 hours | 12 hours | 24 hours | 1b | single | Ans. 6 hours | Radiology | null |
96483df6-39b3-4ade-a3d5-a81bb869ad1f | Which disease is caused by anti-phospholipase 2 antibody: | MPGN | MGN | FSGN | MCD | 1b | single | Ans. b. MGNMEMBRANOPROLIFERATIVE GLOMERULONEPHRITIS (MPGN)Type I--subendothelial immune complex (IC) deposits with granular IF; "tram-track" appearance on PAS stain (See figure A) and HandE stain (See figure B) due to GBM splitting caused by mesangial in growth.Type II--also called dense deposit disease.MPGN is a nephr... | Pathology | Kidney |
f51bf26b-fbdf-4f31-ae98-14eb0edcd411 | Which of the following bacteria act by increasing cAMP | Staphylococcus aureus | E. coli heat stable toxin | Vibrio cholera | Salmonella | 2c | single | Cholera produces a potent enterotoxin known as cholera toxin.
This toxin consists of | Microbiology | null |
a125ec2b-de90-4623-a1ef-999292b6c35a | In strychnos nux vomica poisoning - | Pt becomes unconscious immediately | Pt remains conscious throughout | Pt becomes unconscious at end stage | Pt becomes unconscious in 1 hr or so | 1b | single | consciousness is not lost and the mind remains clear till death.the duration of convulsions varies for half to two minutes REF;THE SYNOPSIS OF FORENSIC MEDICINE:KS NARAYANA REDDY;28th EDITION;PAGE NO 353 | Forensic Medicine | Poisoning |
793539d2-5e54-40ad-9804-5b494078afd6 | Formation of primary ovary in female foetus takes place by | 6th week | 8th week | 10th week | 12th week | 2c | single | C i.e. 10 weeks | Anatomy | null |
dc0a73e6-fc1f-4223-be5b-fefb9ead44e9 | Which of the following malignant tumours is radioresistant? | Ewing's sarcoma | Retinoblastoma | Osteosarcoma | Osteosarcoma | 2c | single | Ans. Osteosarcoma | Radiology | null |
cd5243de-0a5c-4b48-842c-8fb5afcfb99f | Surgical treatment for asymptomatic uterine myoma is indicated if : | The myoma is pedunculated | Tumour is larger than the size of 3 months pregnancy | Diagnosis is unceain | All of the above | 3d | multi | All of the above | Gynaecology & Obstetrics | null |
4c919056-b63b-4e05-8bed-26338adf12b4 | Lateral medullary syndrome is due to the occlusion of which of the following vessels? | Posterior superior cerebellar aery | Anterior inferior cerebellar aery | Basilar aery | Veebral aery | 3d | single | Lateral medullary syndrome is otherwise known as Wallenberg's syndrome or PICA syndrome or veebral aery syndrome. Occlusive disease of the intracranial segment of the veebral aery is a much more frequent cause of the lateral medullary syndrome. Signs and symptoms include: Ipsilateral side Horner's syndrome Decrease in ... | Medicine | All India exam |
e4cd8b2c-7da9-4285-aca5-fb6238a7980b | Which of the following drug causes pain on injection:- | Rocuronium | Vacuronium | Rapocuronium | Atracurium | 0a | single | Rocuronium causes pain on injection, like propofol. Unlike propofol however it is given after patient is induced. Pain associated with injection of rocuronium is commonand can be very distressing. Tracheal intubation with rocuronium using the 'timing principle'. the described pain is a 'burning' in nature and occurred ... | Anaesthesia | Neuromuscular Blocker |
a4e5be8a-f416-42b8-ac74-71cc020398ce | All are stages of anaesthesia except | Analgesia | Allodynia | Delirium | Surgical anesthesia | 1b | multi | Guedel's classification is a means of assessing of depth of general anesthesia introduced by Ahur Ernest Guedel for Ether in1937. Stage I (stage of analgesia or disorientation) Stage II (stage of excitement or delirium) Stage III (stage of surgical anesthesia) plane I to IV Stage IV: from stoppage of respiration till d... | Anaesthesia | General anaesthesia |
0757d89a-114e-4bfc-b937-fe2ec71101c2 | All the following are at-risk groups meriting Hepatitis B vaccination in low endemic areas EXCEPT- | Patients on chronic hemodialysis | Diabetics on insulin | Medical/nursing personnel | Patients with chronic liver disease | 1b | multi | high prevalence of hepatitis B in ceain locality and dialysis units, together with the recent discovery of occult hepatitis B infection, vaccination of non-immune clinical staff and renal patients preferably before the development of advanced renal failure appears paicularly impoant in the control of HBV Ref Davidson e... | Medicine | G.I.T |
38b0c1a2-56dd-46b2-bc5a-5d2746e79005 | A 12-year-old boy develops fever, accompanied by occasional headaches, malaise, fatigue, and nausea a month after being bitten by a dog. One day later, he experiences episodes of rigidity, hallucinations, breath-holding, and difficulty swallowing because of uncontrollable oral secretions. Dr. Louis Pasteur is consulted... | Multinucleate giant cells | Negri bodies | Perivascular lymphocytes | Pseudocysts with bradyzoites | 1b | multi | The child had rabies, an infectious disease in which the virus travels from the site of an infected animal bite up nerves to the CNS. Pathognomonic Negri bodies are cytoplasmic inclusions found in the hippocampal pyramidal cells and cerebellar Purkinje cells. Worldwide, unvaccinated dogs remain the most common vector f... | Pathology | Central Nervous System |
b9f5ee4c-188b-4993-85b5-55e48d9f020a | A patient is being evaluated for jaundice and liver fibrosis. His AST=87 IU/mL and ALT=81 IU/mL. His serological tests are given below. Which of the following is the next step in the diagnosis? IgM Anti- HbcAg Non- reactive IgG Anti- HbcAg Reactive HbsAg Non-Reactive HBeAg Non-Reactive Anti-HCV Reactive | HBV DNA | Anti- HbsAg | HCV-RNA-PCR | Liver biopsy | 2c | multi | The serological status of this patient shows HCV infection since anti-HCV antibody is reactive. Hepatitis B surface antigen is negative and IgG Anti- HBcAg is reactive indicating remote infection with hepatitis B. Recovery is the rule in hepatitis B. In contrast hepatitis C results in development of cirrhosis. Even if ... | Medicine | Hepatitis |
7823935d-437e-4df7-a9e1-9324856c43d8 | Which one of the tissues putrefies late: | Brain | Prostate | Liver | Stomach | 1b | single | Ans. is 'b' i.e. prostateRef. Parik 6th/e p3.26 (5th/e p164)Prostate & testis in male and non gravid uterus and ovaries in female are the last organs to putrefy:As a general rule organs show putrefaction in following order:Larynx and TracheaStomach intestine and spleenLiver, LungsBrainHeartKidney, bladder, uterus, pros... | Forensic Medicine | Misc. |
02e6af69-4ef7-4241-99e7-5bc9d7b9d7a6 | In the stage of Grey hepatization - | WBC's fill the alveoli | RBC's fill the alveoli | Organisms fill the alveoli | Accumulation of fibrin | 3d | single | Pathological changes of bacterial pneumonia
A. Lobar pneumonia
Large confluent area of the lung or entire lobes is consolidated.
The lower lobes are affected most commonly.
There are four stages of the inflammatory response (Laennec's stages) -
1. Stage of congestion (initial phase)
The affected lobe is enlarged, h... | Pathology | null |
de42732e-8945-45b0-ace5-45dc3d0ea099 | Carboxylases require | Vitamin B1 | Vitamin B2 | Vitamin B12 | Vitamin B7 | 3d | single | Biotin, vitamin B7, or vitamin H, is a water-soluble vitamin. The vitamin plays a role in the transferring of carbon dioxide in the metabolism of fat, carbohydrate and protein by functioning as an enzyme cofactor. It is involved in multiple biochemical reactions including niacin metabolism, amino acid degradation, and ... | Biochemistry | Enzymes |
a32f8471-900f-4f90-a851-de5129392196 | All are principles of primary health care except – | Intersectoral coordination | Community participation | Appropriate technology | Decentralised approach | 3d | multi | There are 4 main principles of primary health care :
Equitable distribution
Community participation
Intersectorial coordination
Appropriate technology | Social & Preventive Medicine | null |
24bee4da-88a7-4d3d-87bc-385338682cd3 | IPC for death after aboion is ? | 312 | 314 | 313 | 304 | 1b | single | Ans. is 'b' i.e., 314 314 IPC : Death of patient caused by miscarriage (10 years of imprisonment +- fine). | Forensic Medicine | null |
928dc5d4-5a5b-4512-ae6b-7a6a4ec751fc | If the maxillary canine is denoted as 23, which of the following tooth numbering systems was used? | Palmer system | Zsigmondy system | Universal system | FDI system | 3d | single | The FDI two-digit system was introduced in 1970 by the Federation Dentaire Internationale (now known as the FDI World Dental Federation). It is a wholly digital system of tooth notation that makes visual sense, cognitive sense, and computer sense. This notation is also known as ISO-3950 notation.
FDI World Dental Feder... | Dental | null |
e60bf1ed-5477-47eb-a070-95624035577b | True about cryptosporidium parum - | Affect only in immunocompromised patient | It is one of the common oppounistic infection in AIDS | Cyst size 12-15 mm | AFB (+)ve cyst | 1b | multi | Cryptosporidium has assumed great impoance as a frequent cause of intractable diarrhoea in AIDS patients. It can lead to acute self-limited diarrhoea in previously healthy persons and chronic life-threatening diarrhoea in immunocompromised subjects.Infection is acquired by ingesting the oocyst in contaminated food or d... | Microbiology | parasitology |
e2dd2590-9501-48df-91d1-441af3086a8d | Passavant's ridge is formed by | Superior constrictor and palatopharyngeus | Inferior constrictor and palatopharyngeus | Superior constrictor and palatoglossus | Inferior constrictor and palatoglossus | 0a | single | It is a mucosal ridge raised by fibres of palatopharyngeus. It encircles the posterior and lateral walls of the nasopharyngeal isthmus.
Soft palate, during its contraction, makes firm contact with this ridge to cut off nasopharynx from the oropharynx during the deglutition or speech. | ENT | null |
6b504a83-bb3f-4387-b65a-8552255e353f | Design of the major connector must be determined at the time of: | Primary impression making. | Treatment planning. | At the time of the final impression making. | Any of the above. | 1b | multi | Design of the major connector must be determined during diagnostic and treatment planning phase, because mouth preparation procedures depend in part on the contemplated design of major connectors. | Dental | null |
d10bac4e-edba-425e-8ecd-5a611bfa789a | Na &/or K+ is/are involved in mechanism of action of which of the following receptor(s)? | Dopamine | Nm receptor | Nn receptor | All of the above | 3d | multi | The sodium-potassium pump is found in many cell (plasma) membranes. Powered by ATP, the pump moves sodium and potassium ions in opposite directions, each against its concentration gradient. In a single cycle of the pump, three sodium ions are extruded from and two potassium ions are impoed into the cell Ref: guyton and... | Physiology | Nervous system |
eb623974-70ff-4615-bd69-43b7ecdc47cb | Oedipus complex (given by Sigmund Freud) is seen in: | Boys of 1-3 years of age | Girls of 1-3 years of age | Boys of 3-5 years of age | Girls of 3-5 years of age | 2c | single | Sigmund Freud described Oedipus complex for both sexes, however that term in mostly associated with male sex now a days. Sl No Phase Age Organ of Gratification 1 Oral Phase Bih - 1 1/2 years Oral Region 2 Anal Phase 1 1/2 - 3 years Anal and perianal area 3 Phallic phase 3 to 5 years Genital area Males: Sexual gratifica... | Psychiatry | Psychoanalysis |
28e2b34e-ec44-4dcf-8b24-077528e19bf0 | Alpha fetoprotein is genetically and structurally- | Albumin | Transferrin | Fibrinogen | Growth hormone related | 0a | multi | Produced by immature liver cells in fetus. Seen in amniotic fluid and maternal blood stream. Helps to detect congenital disorders. Source-robbins | Pathology | General pathology |
900a3b09-3309-4053-b992-8d79b2057f99 | A diabetic patient develops cellulitis due to staphy-lococcus aureus that was found to be methicillin resistant on the antibiotic sensitivity testing.All of the following antibiotics will be appropriate EXCEPT: | Vancomycin | Imipenem | Teicoplanin | Linezolid | 1b | multi | lmipenem: It is an extremely potent and broad-spectrum Beta-lactam antibiotic whose range of activity includes grampositive cocci, Enterobacteriaceae, Ps. aeruginosa, Listeria as well as anaerobes like Bact. fragilis and Cl. difficile. It is resistant to most Beta-lactamases; inhibits penicillinase producing staphyloco... | Pharmacology | Chemotherapy |
6c5c3484-0891-4729-86ba-841f7014b1eb | A case of Bell's palsy on steroids, shows no improvement after two weeks. Next step in manangement is - | Vasodilators and ACTH | Physiotherapy | Steroids dose | Electrophysiological nerve testings | 3d | multi | In a patient who has had no improvement in steroids after 2 weeks of use will not benefit from an increase in dose of steroid
Also vasodilators and ACTH have no role in management of Bells palsy
Hence they are also ruled out.
So now we are left with 2 options vizi.
Electrophysiological nerve testing
ii. Surgical decomp... | ENT | null |
16a52407-9ecc-40f7-a319-3d8c8d9079f4 | Fetal growth is maximally affected by – | Insulin | Growth hormone | Cortisol | Thyroxine | 0a | multi | Insulin and insulin like growth factor stimulate fetal growth.
Thyroxine has no effect on linear growth but it has effect on skeletal maturation.
Fetal or maternal GH is not essential for fetal growth in utero. | Pediatrics | null |
64e9c5f4-407f-4905-b4e8-4df3f05b0fdf | Which of the following is the mechanism of action of allopurinol? | Inhibits the synthesis of uric acid | Inhibits tubular reabsorption of uric acid | Anti-inflammatory action | Increases phagocytosis of urate crystals | 0a | multi | Allopurinol (hypoxanthine analog) and recently approved drug, febuxostat (a non-purine drug) decrease the production of uric acid by inhibiting the enzyme xanthine oxidase. Allopurinol is metabolized by the same enzyme to alloxanthine which is a long acting inhibitor of xanthine oxidase. These are indicated as drug of ... | Pharmacology | NSAIDs, Gout and Rheumatoid Ahritis |
e56a157b-d74d-4d66-b3a9-d2073400ab2e | Sodium content in mmol/L in WHO oral rehydration solution is- | 20 | 80 | 90 | 111 | 1b | single | Reduced osmolarity ORS grams/litre Reduced osmolarity ORS mmol/litre Sodium chloride 2.6 Sodium 75 Glucose, anhydrous 13.5 Chloride 65 Potassium chloride 1.5 Glucose, anhydrous 75 Trisodium citrate, dihydrate 2.9 Potassium 20 Citrate 10 Total Osmolarity 245 | Pediatrics | Fluid and Electrolyte Treatment of Specific Disorders |
78057260-857c-478a-9027-bc6c60bf6163 | A 30 years old male presented with silvery scales on elbow and knee, that bleed on removal. The probable diagnosis is – | Pityriasis | Seborrhoeic dermatitis | Psoriasis | Secondary syphilis | 2c | single | Morphology of papules/plaques in various papulosquamotas disorders
Psoriasis - Erythematous papules and plaques on extensors (elbow & knee
Lichen planus - Violaceous papules with Wickham's striae an flexural surface
Pityriasis rosea - Annular plaques on Trunk
Seborrheic dermatitis - Yellowish, follicular papules on sc... | Dental | null |
087bc458-396b-4d79-b73d-78fe6c781174 | Which of the following vitamin is NOT required from diet? | Nicotinic acid | Ascorbic acid | Vitamin-A | Vitamin-D | 3d | single | Vitamin D is synthesized in the skin. 7-Dehydrocholesterol (an intermediate in the synthesis of cholesterol that accumulates in the skin) undergoes a nonenzymic reaction on exposure to ultraviolet light, yielding previtamin D. This undergoes a fuher reaction over a period of hours to form cholecalciferol, which is abso... | Biochemistry | null |
c5661082-ccb9-4d66-b898-0603de45d174 | The most frequent cause of scalded skin syndrome is: | Staphylococci | Pneumococci | Enterococci | Meningococci | 0a | single | Ans. is 'a' i.e., Straphylococci(Ref: Harrison, 18th/e, p. 1164-1167; Ananthanarayan, 9th/e, p. 199)* Staphylococcal scalded skin syndrome (SSSS) is caused by an exfoliative toxin produced by roughly 5% of Staphylococcus aureus. As the syndrome evolves, an initial infection occurs, commonly at a site such as the oral o... | Microbiology | Bacteria |
2ca02bfd-76c0-47ea-8bc1-48c2bf323128 | True about Ebstein anomaly is ? | Right ventricular dilatation | Right atrial dilatation | Left ventricular dilatation | Left atrial dilatation | 1b | multi | In ebstein anomaly there will be right Atrial dilation to accommodate excess blood Ghai essential of pediatrics ,eighth edition, p.no: 423 | Pediatrics | C.V.S |
da2d5536-3985-4766-96d0-0d42371cff61 | Regarding adenocarcinoma in situ, all are true, except: | Invasive cancer cannot be ruled out without diagnostic excisional procedures | Hysterectomy is preferred for women who have completed childbearing | Frequently extends into the endocervical canal | Negative margins on excised specimen ensures complete resection of the disease. | 3d | multi | Ans. D. Negative margins on excised specimen ensures complete resection of the disease.a. Adenocarcinoma in situ of the uterine cervix is a premalignant glandular condition. Adenocarcinoma in situ is the only known precursor to cervical adenocarcinoma, and appropriate management can prevent the occurrence of invasive d... | Gynaecology & Obstetrics | Miscellaneous (Obs) |
c8b63608-1954-4ae1-8ab6-5ebedbb95f3c | Bronze baby syndrome is caused by: | Phototherapy | Phenobarbitone | Hemosiderosis | Chloramphenicol | 0a | single | Bronze baby syndrome: is a dark, grayish brown skin discoloration mainly seen in infants with elevated conjugated bilirubin, as an adverse effect of phototherapy | Pediatrics | Neonatal Jaundice |
bd8a3465-50cd-4beb-8010-a1aa1ddeb5d8 | Cyanide odor is of: NEET 13 | Rotten egg | Fishy | Fruity | Bitter almond | 3d | single | Ans. Bitter almond | Forensic Medicine | null |
587ef917-abf4-4b32-985c-e2020bd397cb | Anaerobic glycolysis of which of these produces 3 ATPs per unit glucose consumed? | Amino acid | Fructose | Galactose | Glycogen | 3d | single | Answer- D. GlycogenAnaerobic glycolysis of glycogen produces 3 ATPs per unit glucose consumed.Consumption of ATP at the level of hexokinase is not required when we sta from glycogen as a substrate. As there is no glucose-6- phosphatase in muscle, glucose-6-phosphate directly enters into glycolysis. Hence, net ATPs are ... | Biochemistry | null |
b0bac4e4-70ba-4e7c-85fc-a05469744bab | A young man with blurring of vision in right eye, followed by left eye after 3 months, showing disc hyperemia, edema, circumpapillary telangiectasia with normal pupillary response with centrocecal scotoma on perimetry, the cause is - | Typical optic neuritis | Acute Papilledema | Toxic optic neuropathy | Leber's hereditary optic neuropathy | 3d | single | It is a type of hereditary optic neuritis which primarily affects males around the age of 20 years. It is transmitted by the female carriers. The condition is characterised by progressive visual failure. The fundus is initially normal or in the acute stage disc may be mildly hyperaemic with telangiectatic microangiopat... | Ophthalmology | Neuro-ophthalmology |
b24fa456-4068-4f81-9429-465d27d1b9be | If both parents are sickle cell anemia patients then the likelyhood of offsprings having the disease is-( | 1 0 % | 25% | 50% | 100% | 3d | multi | Ans. is 'd' i.e., 100% | Pathology | null |
f0cefc9d-0812-4239-ad3e-df12e6400af7 | Foster Kennedy syndrome is associated with all(o\\fBtLh)e following, except: | Ipsilateral Anosmia | Contralateral Optic Atrophy | Olfactory groove meningioma | Contralateral Papilloedema | 1b | multi | Answer is B (Contralateral optic Atrophy): Foster Kennedy Syndrome is associated with ipsilateral optic atrophy and not contralateral optic atrophy The Foster Kennedy syndrome consists of ipsilateral anosmia, ipsilateral optic atrophy and contralateral papilledema | Medicine | null |
9ec14d8a-8f21-407c-a6d3-eccc75ae3a96 | Which of the following anti-cancer drug comes under monoclonal antibodies: March 2013 | Di-ethyl-stilbestrol | Tamoxifen | Ritumixab | Boezomib | 2c | single | Ans. C i.e. Ritumixab Rituximab It is a chimeric monoclonal antibody against the protein CD20, which is primarily found on the surface of B cells. Rituximab destroys B cells, and is therefore used to treat diseases which are characterized by excessive numbers of B cells, overactive B cells, or dysfunctional B cells. Th... | Pharmacology | null |
8bddacd4-978d-48c3-8cc1-2bd668f77620 | Which one of the following statements concerning Loose Connective Tissue is true? | It is less abundant than Dense Connective Tissue. | It has a lower propoion of cells to fibers than does Dense Connective Tissue. | It acts as a medium for exchange of nutrients and wastes between the blood and tissues. | It provides structural suppo for organs. | 2c | multi | Both Loose and Dense connective tissues are composed of three elements: an amorphous ground substance, fibers, and various types of cells. The Amorphous ground substance of Loose Connective Tissue is the medium of exchange between the connective tissue cells and the bloodstream. Lower propoion of cells to fibers is a f... | Anatomy | Glands & Connective tissue |
59359832-dffc-423d-9110-8674a1b05501 | The term applied when it is doubtful whether there will be space for all the teeth in mixed dentition analysis is: | Space maintenance | Space regaining | Space supervision | None of the above | 2c | multi | Space supervision
It is a term applied when it is doubtful, according to the mixed dentition analysis, whether there will be room for all the teeth.
Prognosis for supervision is always questionable, where as prognosis is always good for regaining space and for space maintenance.
Space supervision cases are those that... | Dental | null |
379e2054-89df-4de5-bec3-805a77568e13 | Diagnostic accuracy of a test is determined by its | Sensitivity | Specificity | Predictive value | Odds ratio | 2c | single | (Refer: K. Park's Textbook of Preventive and Social medicine, 24thedition, pg no: 149) | Anatomy | All India exam |
7f6b2c4f-894b-4215-ad2d-806f2949b11b | Floating water–Lily sign is feature of – | Lung hydatid | Bronchial adenoma | Lung abscess | Aspergilloma | 0a | single | Water - Lily sign, also refered as camalote sign, is seen in ruptured hydatid cyst (echinococcosis) of lung. | Radiology | null |
da529e73-61fe-4b52-81b1-8686b6a62ffd | A patient is taking drugs for rheumatoid ahritis and has a history of cataract surgery 1 year back, the patient presented with sudden painless loss of vision, probable diagnosis is? | CME | Macularhole | Chloroquine toxicity | Chronic choroiditis | 2c | single | Patient of rheumatoid ahritis are given hydroxychloroquine which cause painless loss of vision due to bull's eye maculopathy characterized by a foveolar island of pigment surrounded by a depigmented zone of RPE atrophy, which is itself encircled by a hyperpigmented ring (A). There is moderate to severe reduction in VA ... | Ophthalmology | AIIMS 2018 |
07027106-89d0-4ceb-ac05-16a91fcecb2f | The posterior iliac horn is characteristic of: | Nail-patella syndrome | Marfan's syndrome | Hurler syndrome | Acromegaly | 0a | single | Ans. Nail-patella syndrome | Radiology | null |
3c859fe3-16ba-413f-9ba9-6bb852498eb1 | Which of the following is a known effect of dengue to fetuses, if mother is affected | Aboion | Teratogenicity | GR | None of the above | 3d | multi | Answer is option 4 None of the above Fetal risks in Dengue fever in pregnancy includes : No evidence of teratogenicity, aboion or IUGR following Dengue in pregnancy Veical transmission is present Newborn presents with fever hepatomegaly and thrombocytopenia. In grave infection Newborn may show coagulopathy | Gynaecology & Obstetrics | Medical, surgical and gynaecological illness complicating pregnancy |
4936a1ce-daa0-4368-abbf-6ab85ac99809 | True regarding respiratory center is | Directly stimulated by fall in PaO2 | Inhibited during swallowing | Connected with cardiac center | Situated in midbrain | 1b | multi | B i.e. Inhibited during swallowing | Physiology | null |
56601e96-ed43-4630-b087-4e9c071ac494 | The infectivity, of chicken pox lasts for - | Till the last scab falls off | 6 days after onset of rash | 3 days after onset of rash | Till the fever subsides | 1b | multi | Ans. is 'b' i.e., 6 days after onset of rash | Social & Preventive Medicine | null |
e1feef9b-b067-41e2-8f93-f468c6954759 | Which Couinaud segment of liver has independent supply? | I | II | III | IV | 0a | single | Ans. is 'a' i.e., I * Caudate lobe (Couinaud Segment I) (anatomical part of right lobe) belongs physiologically to both right and left lobes because it receives blood from right and left hepatic arteries; right and left branches of portal vein; and drains bile into both right and left hepatic duct. Thus it is considere... | Anatomy | Abdomen & Pelvis |
ae7cc188-d8c3-476f-99d1-33e64a5aa1e0 | Tom Smith septic ahritis affects | Hip of infants | Joint of children | Shoulder in children | Neck of infants | 0a | single | Septic ahritis of hip seen in infants. At this age, the head of the femur is cailaginous and is rapidly and completely destroyed by the pyogenic process. Onset is acute with rapid abscess formation, which may burst out or be incised and heals rapidly. Usually it is mistaken as a superficial infection and the child pres... | Surgery | Trauma |
a2198ccd-d0c0-47da-8b40-667c9df0658f | Residual chlorine in chlorination of water should be: | 1 mg/L after 1 hr | 0.5 mg/L after 1 hr | 1 mg/L after 30 mins | 0.5 mg/L after 30 mins | 1b | single | The minimum recommended concentration of free chlorine is 0.5 mg/L for one hour. The sum of the chlorine demand of the specific water plus the free residual chlorine of 0.5 mg/L constitutes the correct dose of chlorine to be applied. The chlorine has no effect on spores, protozoal cysts and helminthic ova, except in hi... | Social & Preventive Medicine | null |
9ed679cf-84d1-4050-b4f7-9100a433698e | In Ramsay Hunt syndrome, most commonly involved nerve is | V | VII | VIII | IX | 1b | single | Ramsay Hunt syndrome affects V, VII and VIII cranial nerves and among them, VII is most commonly affected. Ref: Dhingra 6th edition pg. 96 | ENT | Ear |
c2eb6d09-8523-43b0-8fd0-f1cf1525d017 | Anthracosis is caused by; | Silica | Asbestos | Coal dust | Sugar cane waste | 2c | single | Anthracosis is caused by Coal dust. There are two general phases in Anthracosis The first phase is simple pneumoconiosis which is associated with little ventilatory impairment. The second phase is characterised by progressive massive fibrosis (PMF); this causes severe respiratory disability and frequently results in pr... | Social & Preventive Medicine | FMGE 2019 |
30e098ff-d0bf-427f-8f1f-cb94441d2df0 | All of the following are indication for adjuvant radiotherapy in head neck cancers except:- | Multiple lymph node disease | Extranodal involvement | Lymphovascular invasion | Lymph node >3cm | 3d | multi | Lymph node >3cm is not an indication for adjuvant radiotherapy in head neck cancers. Indications for postoperative include:- -positive margins -invasion of the soft tissues of the neck -extranodal involvement - perineural invasion, and -more than 5 mm of subglottic invasion. | Surgery | Facial Injuries and Abnormalities |
fae4b193-54f6-4ccd-9f35-db6ec510ff8d | The most sensitive imaging modality to detect early renal tuberculosis is ? | Intravenous urography | Computed tomography | Ultrasound | Magnetic Resonance Imaging | 0a | single | Ans. is 'a' i.e. Intravenous urography In early renal tuberculosis, the only radiological abnormality may be irregularity or destruction of one or more papillae and the most sensitive modality to detect it is IUV as it can show detailed calyceal anatomy. Advanced changes are :? a) Calcification - this may occur in any ... | Surgery | null |
89270706-e043-4cfe-913d-22234def7c68 | Feature of fetal R.B.C. - | Alkali denaturation resistant | Small in size | Has more 2,3 DPG level | More iron than adult RBC | 0a | multi | <p>Fetal hemoglobin in contrast to Hb A shows the following -increased solubility of deoxy HbF, slower electrophoretic mobility for HbF, increased resistance of HbF to alkali denaturation, HbF has decreased interaction with 2,3-BPG.</p><p>DM Vasudevan textbook of biochemistry sixth edition pg no 259</p> | Medicine | Haematology |
ee3ac036-6513-4b0a-a7f3-6b158504e9bd | Minimum number of lobes required to form a permanent tooth | 1 | 2 | 3 | 4 | 3d | single | For permanent dentition | Dental | null |
dfcd3099-923b-4165-9f8b-efb19ce11dd7 | A five day old, full term male infant was severely cyanotic at bih. Prostaglandin E was administered initially and later ballooned atrial septosomy was done which showed improvement in oxygenation. The most likely diagnosis of this infant is - | Tetralogy Fallot | Transposition of great vessels | Truncus Aeriosus | Tricuspid Atresia | 1b | multi | Ans. is 'b' i.e., Transposition of great vessels Transposition of Great vessels is a condition characterized by aoa arising from the right ventricle and pulmonary aery from the left ventricle. This results in complete separation of systemic and pulmonary circulation. Since systemic and pulmonary circulations are separa... | Pediatrics | null |
a5f9fa8a-b146-4ab1-aee3-c262704e3e95 | Which of the following antibiotic is the drug of choice in the treatment of lymphedema? | Penicillin | Amikacin | Metronidazole | Ceftazidime | 0a | single | Penicillin 500mg given three to four times daily is the drug of choice in the treatment of lymphedema. Most common organisms causing soft tissue infection in patients with lymphedema are Staphylococcus and beta hemolytic Streptococcus. Lymphedema is a chronic condition caused by ineffective lymphatic transpo which resu... | Surgery | null |
06fe91ba-d1b1-47b9-b54a-6bfafbafc800 | Best skin disinfectant for central line insertion is: | Povione iodine | Alcohol | Cetrimide | Chlorhexidine | 3d | single | "Chlorhexidine is now the disinfectant recommended for all catheter placement procedures and for routine site cleansing during dressing changes."- Comprehensive Hospital Medicine: An Evidence-Based And Systems Approach By Mark V. Williams, Scott A. Flanders, p320
"Use of antiseptic solution for skin disinfection at the... | Surgery | null |
2b7ccc36-2d82-404b-807c-04be6cd0a022 | MalloryY hyaline is seen in | Alcoholic liver disease | Hepatocellular carcinoma | Wilson's disease | All of the above | 3d | multi | Mallory bodies or alcoholic hyalin: These are eosinophilic, intracytoplasmic inclusions seen in perinuclear location within swollen and ballooned hepatocytes. They represent aggregates of cytoskeletal intermediate filaments (prekeratin). They can be best visualised with connective tissue stains like Masson's trichrome ... | Pathology | G.I.T |
799f5cf7-2804-4395-9540-922089158b80 | Kallu a 22 years old male suffers from decreased sleep, increased sexual activity, excitement and spending excessive money for last 8 days. The diagnosis is: | Confusion | Disorientation | Hyperactivity | Loss of memory | 2c | multi | C i.e. Hyperactivity | Psychiatry | null |
c779e460-3d57-4683-b7a8-abc37446ee34 | Size of uterus in inches is : | 5x4x2 | 4x3x1 | 3x2x1 | 4x2x1 | 2c | single | 3x2x1 | Gynaecology & Obstetrics | null |
34b9ad41-1bb4-45b2-b95b-cb1bbf1d602a | Infectious mononucleosis is confirmed by | Blood smear | Monospot test | Frei’s test | Hess test | 1b | single | Monospot test is also known as Paul Bunnel test. | Microbiology | null |
3e531943-eafa-47f8-9281-246e546816c9 | The distance between the gingiva and the margin of the free end of the stainless steel crown should be: | 0.5 mm below | 0.5-1.0 mm below | 0.5 mm above | 0.5- 1.0 mm above | 1b | multi | The stainless steel crown should be approximately 0.5 to 1 mm beneath the free margin of the gingival tissue. | Dental | null |
f043a8cf-a59a-424b-a33b-5348302c80b8 | A 7 years old girl with falling grades and complaints by teacher that she is inattentive in class to her parents and has bad school performance. On hyperventilation her symptoms increased and showed the following EEG findings. Diagnosis is (graph is given): | Myoclonic epilepsy | Myoclonus | Absence seizure | Juvenile myoclonic epilepsy | 2c | multi | Ans. c. Absence seizures | Pediatrics | null |
7cdb5553-095d-4f85-bc02-13ff25041ad5 | Origin of sympathetic fibers ? | Cranial | Sacral | Dorsolumbar | None | 2c | multi | Ans. is 'c' i.e., Dorsolumbar | Anatomy | null |
d2cb68ff-0fb2-48fe-9cdb-f0fed627ad92 | Which of the following is not a constituent of Glycosphingolipid | Sphingosine | Fatty acid | Glycerol | Carbohydrate | 2c | single | Glycosphingo lipid are made up of
Sphingosine + Fatty acid + Carbohydrate group.
eg:- Cerebrosides, Gangliosides, Glubosides. | Biochemistry | null |
d7356a09-d2d2-4a60-9aa0-4fc56b563190 | Which of the following organism causes a life-threatening gastroenteritis as a result of use of a broad spectrum antimicrobial agents | Bacillus cereus | Bacillus anthracis | Clostridium botulinum | Clostridium difficile | 3d | single | The use of broad spectrum antibiotics such as ampicillin and clindamycin has been associated with pseudomembranous colitis. Antibiotic administration results in the proliferation of drug resistant C. difficile that produces Toxin A (a potent enterotoxin with cytotoxic activity) and Toxin B (a potent cytotoxin). This di... | Microbiology | Bacteriology |
64500408-3e92-4373-9748-6ff150d03ec6 | Anti-parietal cell antibodies are found in patients with? | Good-pasture syndrome. | Primary biliary cirrhosis | Wegener granulomatosis. | Pernicious anemia | 3d | single | Ans. (d) Pernicious anemiaRef: Robbin's pathology 9th ed. /764* Anti-parietal cell antibodies are found in patients with the autoimmune disease known as pernicious anemia.* The anti-neutrophilic cytoplasmic antibodies are found in patients with Wegener granulomatosis.* Wegener granulomatosis may also present with pulmo... | Pathology | Stomach |
cb60946d-4ff7-4f07-a182-01385e941dfa | Direct standardisation is also known as | Changing base method | Fixed base method | Hanging base method | None of the above | 1b | multi | DIRECT STANDARDIZATION Two examples of direct standardization are given. In the first, a "standard population" is selected. A standard population is defined as one for which the numbers in each age and sex group are known. A frequently used standard age-composition is shown in Table 3. The standard population may also ... | Social & Preventive Medicine | Biostatistics |
0bcb65a7-5d10-423d-9d69-b419b8e0ae2d | Drug used to control secretions in GA: | Hyoscine | Glycopyrrolate | Pethidine | Lorazepam | 1b | single | Ans. (b) GlycopyrrolateRef: Ajay yadav's anesthesia 4th ed./48* To control secretions, anti-cholinergics are used: Glycopyrrolate, Atropine and Scopolamine.* Glycopyrrolate is preferred over atropine and scopolamine because it doesn't cross blood brain barrier. Therefore it is devoid of central side effects.Drugs Used ... | Anaesthesia | Miscellaneous General Anesthesia |
119e1434-41fd-4e11-b7cb-dfa837b80ad4 | All are true about whiplash injury except : | Neck stiffness is a presenting symptom | X-ray shows veebral fracture in most cases | There is hyperextension followed by flexion | It is a ligamentous injury of the cervical spine | 1b | multi | Whiplash injury: Collision causing the occupant's body to be forced against the car seat, while the head flips backwards causing hyperextension and then recoil into flexion. C/F: Neck pain and stiffness, headache, dizziness, blurring of vision, paraesthesia in the arms, Temporomandibular discomfo and tinnitus. Tenderne... | Orthopaedics | Spinal Injury |
e9ad66fe-0c0c-46c3-98d8-2032a5e0d0dd | A young child presented with history of passage of dark colored with urine with reduced urine output. He has a past history of abdominal pain, fever, and bloody diarrhea for 4 days which resolved on its own. There is absence of peripheral edema or rashes. Investigations show anemia, thrombocytopenia, and elevated blood... | Elevated haptoglobin level | Elevated serum indirect bilirubin | Elevated thrombin and prothrombin time | Low fibrinogen and elevated D-dimer level | 1b | single | - Child given is presenting with classical history of hemolytic uremic syndrome In HUS, there is initial history of diarrhea caused d/t E-coli which causes damage to endothelial cells resulting in thrombotic microangiopathy affecting kidney. Typical Causative agent: Escherichia coli strain O157:H7 infection; Endothelia... | Pathology | Hemolytic Anemias: Basic concepts and classification |
f6af5dd4-d33d-46b2-8558-3ebcf8931da3 | A pregnant lady in her first trimester presents with vaginal bleeding. On examination the os is closed and uterine size corresponds to the period of amenorrhoea. The condition could be: | Septic aboion | Complete aboion | Inevitable aboion | Threatened aboion | 3d | single | Aboion Classification Characteristics Cervical Os Passage of Fetal Tissue Threatened Abdominal pain or bleeding in the first 20 weeks of gestation Closed None Inevitable Abdominal pain or bleeding in the first 20 weeks of gestation Open None Incomplete Abdominal pain or bleeding in the first 20 weeks of gestation Open ... | Gynaecology & Obstetrics | Aboions, Spontaneous & Induced Emergency Contraception (Hey,whats the hurry !) |
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