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A public genome sequencing effort of cotton was initiated in 2007 by a consortium of public researchers. They agreed on a strategy to sequence the genome of cultivated, tetraploid cotton. "Tetraploid" means that cultivated cotton actually has two separate genomes within its nucleus, referred to as the A and D genomes. The sequencing consortium first agreed to sequence the D-genome relative of cultivated cotton (G. raimondii, a wild Central American cotton species) because of its small size and limited number of repetitive elements. It is nearly one-third the number of bases of tetraploid cotton (AD), and each chromosome is only present once.[clarification needed] The A genome of G. arboreum would be sequenced next. Its genome is roughly twice the size of G. raimondii's. Part of the difference in size between the two genomes is the amplification of retrotransposons (GORGE). Once both diploid genomes are assembled, then research could begin sequencing the actual genomes of cultivated cotton varieties. This strategy is out of necessity; if one were to sequence the tetraploid genome without model diploid genomes, the euchromatic DNA sequences of the AD genomes would co-assemble and the repetitive elements of AD genomes would assembly independently into A and D sequences respectively. Then there would be no way to untangle the mess of AD sequences without comparing them to their diploid counterparts.
The public sector effort continues with the goal to create a high-quality, draft genome sequence from reads generated by all sources. The public-sector effort has generated Sanger reads of BACs, fosmids, and plasmids as well as 454 reads. These later types of reads will be instrumental in assembling an initial draft of the D genome. In 2010, two companies (Monsanto and Illumina), completed enough Illumina sequencing to cover the D genome of G. raimondii about 50x. They announced that they would donate their raw reads to the public. This public relations effort gave them some recognition for sequencing the cotton genome. Once the D genome is assembled from all of this raw material, it will undoubtedly assist in the assembly of the AD genomes of cultivated varieties of cotton, but a lot of hard work remains.
In signal processing, data compression, source coding, or bit-rate reduction involves encoding information using fewer bits than the original representation. Compression can be either lossy or lossless. Lossless compression reduces bits by identifying and eliminating statistical redundancy. No information is lost in lossless compression. Lossy compression reduces bits by identifying unnecessary information and removing it. The process of reducing the size of a data file is referred to as data compression. In the context of data transmission, it is called source coding (encoding done at the source of the data before it is stored or transmitted) in opposition to channel coding.
Compression is useful because it helps reduce resource usage, such as data storage space or transmission capacity. Because compressed data must be decompressed to use, this extra processing imposes computational or other costs through decompression; this situation is far from being a free lunch. Data compression is subject to a space–time complexity trade-off. For instance, a compression scheme for video may require expensive hardware for the video to be decompressed fast enough to be viewed as it is being decompressed, and the option to decompress the video in full before watching it may be inconvenient or require additional storage. The design of data compression schemes involves trade-offs among various factors, including the degree of compression, the amount of distortion introduced (when using lossy data compression), and the computational resources required to compress and decompress the data.
Lossless data compression algorithms usually exploit statistical redundancy to represent data without losing any information, so that the process is reversible. Lossless compression is possible because most real-world data exhibits statistical redundancy. For example, an image may have areas of colour that do not change over several pixels; instead of coding "red pixel, red pixel, ..." the data may be encoded as "279 red pixels". This is a basic example of run-length encoding; there are many schemes to reduce file size by eliminating redundancy.
The Lempel–Ziv (LZ) compression methods are among the most popular algorithms for lossless storage. DEFLATE is a variation on LZ optimized for decompression speed and compression ratio, but compression can be slow. DEFLATE is used in PKZIP, Gzip and PNG. LZW (Lempel–Ziv–Welch) is used in GIF images. Also noteworthy is the LZR (Lempel-Ziv–Renau) algorithm, which serves as the basis for the Zip method.[citation needed] LZ methods use a table-based compression model where table entries are substituted for repeated strings of data. For most LZ methods, this table is generated dynamically from earlier data in the input. The table itself is often Huffman encoded (e.g. SHRI, LZX). Current LZ-based coding schemes that perform well are Brotli and LZX. LZX is used in Microsoft's CAB format.
In a further refinement of the direct use of probabilistic modelling, statistical estimates can be coupled to an algorithm called arithmetic coding. Arithmetic coding is a more modern coding technique that uses the mathematical calculations of a finite-state machine to produce a string of encoded bits from a series of input data symbols. It can achieve superior compression to other techniques such as the better-known Huffman algorithm. It uses an internal memory state to avoid the need to perform a one-to-one mapping of individual input symbols to distinct representations that use an integer number of bits, and it clears out the internal memory only after encoding the entire string of data symbols. Arithmetic coding applies especially well to adaptive data compression tasks where the statistics vary and are context-dependent, as it can be easily coupled with an adaptive model of the probability distribution of the input data. An early example of the use of arithmetic coding was its use as an optional (but not widely used) feature of the JPEG image coding standard. It has since been applied in various other designs including H.264/MPEG-4 AVC and HEVC for video coding.
Lossy data compression is the converse of lossless data compression. In these schemes, some loss of information is acceptable. Dropping nonessential detail from the data source can save storage space. Lossy data compression schemes are designed by research on how people perceive the data in question. For example, the human eye is more sensitive to subtle variations in luminance than it is to the variations in color. JPEG image compression works in part by rounding off nonessential bits of information. There is a corresponding trade-off between preserving information and reducing size. A number of popular compression formats exploit these perceptual differences, including those used in music files, images, and video.
In lossy audio compression, methods of psychoacoustics are used to remove non-audible (or less audible) components of the audio signal. Compression of human speech is often performed with even more specialized techniques; speech coding, or voice coding, is sometimes distinguished as a separate discipline from audio compression. Different audio and speech compression standards are listed under audio coding formats. Voice compression is used in internet telephony, for example, audio compression is used for CD ripping and is decoded by the audio players.
There is a close connection between machine learning and compression: a system that predicts the posterior probabilities of a sequence given its entire history can be used for optimal data compression (by using arithmetic coding on the output distribution) while an optimal compressor can be used for prediction (by finding the symbol that compresses best, given the previous history). This equivalence has been used as a justification for using data compression as a benchmark for "general intelligence."
Data compression can be viewed as a special case of data differencing: Data differencing consists of producing a difference given a source and a target, with patching producing a target given a source and a difference, while data compression consists of producing a compressed file given a target, and decompression consists of producing a target given only a compressed file. Thus, one can consider data compression as data differencing with empty source data, the compressed file corresponding to a "difference from nothing." This is the same as considering absolute entropy (corresponding to data compression) as a special case of relative entropy (corresponding to data differencing) with no initial data.
Audio data compression, not to be confused with dynamic range compression, has the potential to reduce the transmission bandwidth and storage requirements of audio data. Audio compression algorithms are implemented in software as audio codecs. Lossy audio compression algorithms provide higher compression at the cost of fidelity and are used in numerous audio applications. These algorithms almost all rely on psychoacoustics to eliminate less audible or meaningful sounds, thereby reducing the space required to store or transmit them.
Lossless audio compression produces a representation of digital data that decompress to an exact digital duplicate of the original audio stream, unlike playback from lossy compression techniques such as Vorbis and MP3. Compression ratios are around 50–60% of original size, which is similar to those for generic lossless data compression. Lossless compression is unable to attain high compression ratios due to the complexity of waveforms and the rapid changes in sound forms. Codecs like FLAC, Shorten and TTA use linear prediction to estimate the spectrum of the signal. Many of these algorithms use convolution with the filter [-1 1] to slightly whiten or flatten the spectrum, thereby allowing traditional lossless compression to work more efficiently. The process is reversed upon decompression.
Lossy audio compression is used in a wide range of applications. In addition to the direct applications (mp3 players or computers), digitally compressed audio streams are used in most video DVDs, digital television, streaming media on the internet, satellite and cable radio, and increasingly in terrestrial radio broadcasts. Lossy compression typically achieves far greater compression than lossless compression (data of 5 percent to 20 percent of the original stream, rather than 50 percent to 60 percent), by discarding less-critical data.
To determine what information in an audio signal is perceptually irrelevant, most lossy compression algorithms use transforms such as the modified discrete cosine transform (MDCT) to convert time domain sampled waveforms into a transform domain. Once transformed, typically into the frequency domain, component frequencies can be allocated bits according to how audible they are. Audibility of spectral components calculated using the absolute threshold of hearing and the principles of simultaneous masking—the phenomenon wherein a signal is masked by another signal separated by frequency—and, in some cases, temporal masking—where a signal is masked by another signal separated by time. Equal-loudness contours may also be used to weight the perceptual importance of components. Models of the human ear-brain combination incorporating such effects are often called psychoacoustic models.
Other types of lossy compressors, such as the linear predictive coding (LPC) used with speech, are source-based coders. These coders use a model of the sound's generator (such as the human vocal tract with LPC) to whiten the audio signal (i.e., flatten its spectrum) before quantization. LPC may be thought of as a basic perceptual coding technique: reconstruction of an audio signal using a linear predictor shapes the coder's quantization noise into the spectrum of the target signal, partially masking it.
Latency results from the methods used to encode and decode the data. Some codecs will analyze a longer segment of the data to optimize efficiency, and then code it in a manner that requires a larger segment of data at one time to decode. (Often codecs create segments called a "frame" to create discrete data segments for encoding and decoding.) The inherent latency of the coding algorithm can be critical; for example, when there is a two-way transmission of data, such as with a telephone conversation, significant delays may seriously degrade the perceived quality.
In contrast to the speed of compression, which is proportional to the number of operations required by the algorithm, here latency refers to the number of samples that must be analysed before a block of audio is processed. In the minimum case, latency is zero samples (e.g., if the coder/decoder simply reduces the number of bits used to quantize the signal). Time domain algorithms such as LPC also often have low latencies, hence their popularity in speech coding for telephony. In algorithms such as MP3, however, a large number of samples have to be analyzed to implement a psychoacoustic model in the frequency domain, and latency is on the order of 23 ms (46 ms for two-way communication)).
If the data to be compressed is analog (such as a voltage that varies with time), quantization is employed to digitize it into numbers (normally integers). This is referred to as analog-to-digital (A/D) conversion. If the integers generated by quantization are 8 bits each, then the entire range of the analog signal is divided into 256 intervals and all the signal values within an interval are quantized to the same number. If 16-bit integers are generated, then the range of the analog signal is divided into 65,536 intervals.
A literature compendium for a large variety of audio coding systems was published in the IEEE Journal on Selected Areas in Communications (JSAC), February 1988. While there were some papers from before that time, this collection documented an entire variety of finished, working audio coders, nearly all of them using perceptual (i.e. masking) techniques and some kind of frequency analysis and back-end noiseless coding. Several of these papers remarked on the difficulty of obtaining good, clean digital audio for research purposes. Most, if not all, of the authors in the JSAC edition were also active in the MPEG-1 Audio committee.
The world's first commercial broadcast automation audio compression system was developed by Oscar Bonello, an engineering professor at the University of Buenos Aires. In 1983, using the psychoacoustic principle of the masking of critical bands first published in 1967, he started developing a practical application based on the recently developed IBM PC computer, and the broadcast automation system was launched in 1987 under the name Audicom. Twenty years later, almost all the radio stations in the world were using similar technology manufactured by a number of companies.
The majority of video compression algorithms use lossy compression. Uncompressed video requires a very high data rate. Although lossless video compression codecs perform at a compression factor of 5-12, a typical MPEG-4 lossy compression video has a compression factor between 20 and 200. As in all lossy compression, there is a trade-off between video quality, cost of processing the compression and decompression, and system requirements. Highly compressed video may present visible or distracting artifacts.
Some video compression schemes typically operate on square-shaped groups of neighboring pixels, often called macroblocks. These pixel groups or blocks of pixels are compared from one frame to the next, and the video compression codec sends only the differences within those blocks. In areas of video with more motion, the compression must encode more data to keep up with the larger number of pixels that are changing. Commonly during explosions, flames, flocks of animals, and in some panning shots, the high-frequency detail leads to quality decreases or to increases in the variable bitrate.
Video data may be represented as a series of still image frames. The sequence of frames contains spatial and temporal redundancy that video compression algorithms attempt to eliminate or code in a smaller size. Similarities can be encoded by only storing differences between frames, or by using perceptual features of human vision. For example, small differences in color are more difficult to perceive than are changes in brightness. Compression algorithms can average a color across these similar areas to reduce space, in a manner similar to those used in JPEG image compression. Some of these methods are inherently lossy while others may preserve all relevant information from the original, uncompressed video.
The most powerful used method works by comparing each frame in the video with the previous one. If the frame contains areas where nothing has moved, the system simply issues a short command that copies that part of the previous frame, bit-for-bit, into the next one. If sections of the frame move in a simple manner, the compressor emits a (slightly longer) command that tells the decompressor to shift, rotate, lighten, or darken the copy. This longer command still remains much shorter than intraframe compression. Interframe compression works well for programs that will simply be played back by the viewer, but can cause problems if the video sequence needs to be edited.
Because interframe compression copies data from one frame to another, if the original frame is simply cut out (or lost in transmission), the following frames cannot be reconstructed properly. Some video formats, such as DV, compress each frame independently using intraframe compression. Making 'cuts' in intraframe-compressed video is almost as easy as editing uncompressed video: one finds the beginning and ending of each frame, and simply copies bit-for-bit each frame that one wants to keep, and discards the frames one doesn't want. Another difference between intraframe and interframe compression is that, with intraframe systems, each frame uses a similar amount of data. In most interframe systems, certain frames (such as "I frames" in MPEG-2) aren't allowed to copy data from other frames, so they require much more data than other frames nearby.
Today, nearly all commonly used video compression methods (e.g., those in standards approved by the ITU-T or ISO) apply a discrete cosine transform (DCT) for spatial redundancy reduction. The DCT that is widely used in this regard was introduced by N. Ahmed, T. Natarajan and K. R. Rao in 1974. Other methods, such as fractal compression, matching pursuit and the use of a discrete wavelet transform (DWT) have been the subject of some research, but are typically not used in practical products (except for the use of wavelet coding as still-image coders without motion compensation). Interest in fractal compression seems to be waning, due to recent theoretical analysis showing a comparative lack of effectiveness of such methods.
Genetics compression algorithms are the latest generation of lossless algorithms that compress data (typically sequences of nucleotides) using both conventional compression algorithms and genetic algorithms adapted to the specific datatype. In 2012, a team of scientists from Johns Hopkins University published a genetic compression algorithm that does not use a reference genome for compression. HAPZIPPER was tailored for HapMap data and achieves over 20-fold compression (95% reduction in file size), providing 2- to 4-fold better compression and in much faster time than the leading general-purpose compression utilities. For this, Chanda, Elhaik, and Bader introduced MAF based encoding (MAFE), which reduces the heterogeneity of the dataset by sorting SNPs by their minor allele frequency, thus homogenizing the dataset. Other algorithms in 2009 and 2013 (DNAZip and GenomeZip) have compression ratios of up to 1200-fold—allowing 6 billion basepair diploid human genomes to be stored in 2.5 megabytes (relative to a reference genome or averaged over many genomes).
The Sun had the largest circulation of any daily newspaper in the United Kingdom, but in late 2013 slipped to second largest Saturday newspaper behind the Daily Mail. It had an average daily circulation of 2.2 million copies in March 2014. Between July and December 2013 the paper had an average daily readership of approximately 5.5 million, with approximately 31% of those falling into the ABC1 demographic and 68% in the C2DE demographic. Approximately 41% of readers are women. The Sun has been involved in many controversies in its history, including its coverage of the 1989 Hillsborough football stadium disaster. Regional editions of the newspaper for Scotland, Northern Ireland and the Republic of Ireland are published in Glasgow (The Scottish Sun), Belfast (The Sun) and Dublin (The Irish Sun) respectively.
On 26 February 2012, The Sun on Sunday was launched to replace the closed News of the World, employing some of its former journalists. In late 2013, it was given a new look, with a new typeface. The average circulation for The Sun on Sunday in March 2014 was 1,686,840; but in May 2015 The Mail on Sunday sold more copies for the first time, an average of 28,650 over those of its rival: 1,497,855 to 1,469,195. Roy Greenslade issued some caveats over the May 2015 figures, but believes the weekday Daily Mail will overtake The Sun in circulation during 2016.
Research commissioned by Cecil King from Mark Abrams of Sussex University, The Newspaper Reading Public of Tomorrow, identified demographic changes which suggested reasons why the Herald might be in decline. The new paper was intended to add a readership of 'social radicals' to the Herald's 'political radicals'. Launched with an advertising budget of £400,000 the brash new paper "burst forth with tremendous energy", according to The Times. Its initial print run of 3.5 million was attributed to 'curiosity' and the 'advantage of novelty', and had declined to the previous circulation of the Daily Herald (1.2 million) within a few weeks.
Seizing the opportunity to increase his presence on Fleet Street, he made an agreement with the print unions, promising fewer redundancies if he acquired the newspaper. He assured IPC that he would publish a "straightforward, honest newspaper" which would continue to support Labour. IPC, under pressure from the unions, rejected Maxwell's offer, and Murdoch bought the paper for £800,000, to be paid in instalments. He would later remark: "I am constantly amazed at the ease with which I entered British newspapers."
Murdoch found he had such a rapport with Larry Lamb over lunch that other potential recruits as editor were not interviewed and Lamb was appointed as the first editor of the new Sun. He was scathing in his opinion of the Mirror, where he had recently been employed as a senior sub-editor, and shared Murdoch's view that a paper's quality was best measured by its sales, and he regarded the Mirror as overstaffed, and primarily aimed at an ageing readership. Lamb hastily recruited a staff of about 125 reporters, who were mostly selected for their availability rather than their ability.
Sex was used as an important element in the content and marketing the paper from the start, which Lamb believed was the most important part of his readers' lives. The first topless Page 3 model appeared on 17 November 1970, German-born Stephanie Rahn; she was tagged as a "Birthday Suit Girl" to mark the first anniversary of the relaunched Sun. A topless Page 3 model gradually became a regular fixture, and with increasingly risqué poses. Both feminists and many cultural conservatives saw the pictures as pornographic and misogynistic. Lamb expressed some regret at introducing the feature, although denied it was sexist. A Conservative council in Sowerby Bridge, Yorkshire, was the first to ban the paper from its public library, shortly after Page 3 began, because of its excessive sexual content. This decision was reversed after a sustained campaign by the newspaper itself lasting 16 months, and the election of a Labour-led council in 1971.
Politically, The Sun in the early Murdoch years, remained nominally Labour. It supported the Labour Party led by Harold Wilson in the 1970 General Election, with the headline "Why It Must Be Labour" but by February 1974 it was calling for a vote for the Conservative Party led by Edward Heath while suggesting that it might support a Labour Party led by James Callaghan or Roy Jenkins. In the October election an editorial asserted: "ALL our instincts are left rather than right and we would vote for any able politician who would describe himself as a Social Democrat."
The editor, Larry Lamb, was originally from a Labour background, with a socialist upbringing while his temporary replacement Bernard Shrimsley (1972–75) was a middle-class uncommitted Conservative. An extensive advertising campaign on the ITV network in this period, voiced by actor Christopher Timothy, may have helped The Sun to overtake the Daily Mirror's circulation in 1978. Despite the industrial relations of the 1970s – the so-called "Spanish practices" of the print unions – The Sun was very profitable, enabling Murdoch to expand his operations to the United States from 1973.
The Daily Star had been launched in 1978 by Express Newspaper, and by 1981 had begun to affect sales of The Sun. Bingo was introduced as a marketing tool and a 2p drop in cover price removed the Daily Star's competitive advantage opening a new circulation battle which resulted in The Sun neutralising the threat of the new paper. The new editor of The Sun, Kelvin MacKenzie, took up his post in 1981 just after these developments, and "changed the British tabloid concept more profoundly than [Larry] Lamb did", according to Bruce Page, MacKenzie The paper became "more outrageous, opinionated and irreverent than anything ever produced in Britain".
On 1 May, The Sun claimed to have 'sponsored' a British missile. Under the headline "Stick This Up Your Junta: A Sun missile for Galtieri’s gauchos", the newspaper published a photograph of a missile, (actually a Polaris missile stock shot from the Ministry of Defence) which had a large Sun logo printed on its side with the caption "Here It Comes, Senors..." underneath. The paper explained that it was 'sponsoring' the missile by contributing to the eventual victory party on HMS Invincible when the war ended. In copy written by Wendy Henry, the paper said that the missile would shortly be used against Argentinian forces. Despite this, it was not well received by the troops and copies of The Sun were soon burnt. Tony Snow, The Sun journalist on HMS Invincible who had 'signed' the missile, reported a few days later that it had hit an Argentinian target.
One of the paper's best known front pages, published on 4 May 1982, commemorated the torpedoing of the Argentine ship the General Belgrano by running the story under the headline "GOTCHA". At MacKenzie's insistence, and against the wishes of Murdoch (the mogul was present because almost all the journalists were on strike), the headline was changed for later editions after the extent of Argentinian casualties became known. John Shirley, a reporter for The Sunday Times, witnessed copies of this edition of The Sun being thrown overboard by sailors and marines on HMS Fearless.
After HMS Sheffield was wrecked by an Argentinian attack, The Sun was heavily criticised and even mocked for its coverage of the war in The Daily Mirror and The Guardian, and the wider media queried the veracity of official information and worried about the number of casualties, The Sun gave its response. "There are traitors in our midst", wrote leader writer Ronald Spark on 7 May, accusing commentators on Daily Mirror and The Guardian, plus the BBC's defence correspondent Peter Snow, of "treason" for aspects of their coverage.
These years included what was called "spectacularly malicious coverage" of the Labour Party by The Sun and other newspapers. During the general election of 1983 The Sun ran a front page featuring an unflattering photograph of Michael Foot, then aged almost 70, claiming he was unfit to be Prime Minister on grounds of his age, appearance and policies, alongside the headline "Do You Really Want This Old Fool To Run Britain?" A year later, in 1984, The Sun made clear its enthusiastic support for the re-election of Ronald Reagan as president in the USA. Reagan was two weeks off his 74th birthday when he started his second term, in January 1985.
The Sun, during the Miners' strike of 1984–85, supported the police and the Thatcher government against the striking NUM miners, and in particular the union's president, Arthur Scargill. On 23 May 1984, The Sun prepared a front page with the headline "Mine Führer" and a photograph of Scargill with his arm in the air, a pose which made him look as though he was giving a Nazi salute. The print workers at The Sun refused to print it. The Sun strongly supported the April 1986 bombing of Libya by the US, which was launched from British bases. Several civilians were killed during the bombing. Their leader was "Right Ron, Right Maggie". That year, Labour MP Clare Short attempted in vain to persuade Parliament to outlaw the pictures on Page Three and gained opprobrium from the newspaper for her stand.
Murdoch has responded to some of the arguments against the newspaper by saying that critics are "snobs" who want to "impose their tastes on everyone else", while MacKenzie claims the same critics are people who, if they ever had a "popular idea", would have to "go and lie down in a dark room for half an hour". Both have pointed to the huge commercial success of the Sun in this period and its establishment as Britain's top-selling newspaper, claiming that they are "giving the public what they want". This conclusion is disputed by critics. John Pilger has said that a late-1970s edition of the Daily Mirror, which replaced the usual celebrity and domestic political news items with an entire issue devoted to his own front-line reporting of the genocide in Pol Pot's Cambodia, not only outsold The Sun on the day it was issued but became the only edition of the Daily Mirror to ever sell every single copy issued throughout the country, something never achieved by The Sun.
According to Max Clifford: Read All About It, written by Clifford and Angela Levin, La Salle invented the story out of frustration with Starr who had been working on a book with McCaffrey. She contacted an acquaintance who worked for The Sun in Manchester. The story reportedly delighted MacKenzie, who was keen to run it, and Max Clifford, who had been Starr's public relations agent. Starr had to be persuaded that the apparent revelation would not damage him; the attention helped to revive his career. In his 2001 autobiography Unwrapped, Starr wrote that the incident was a complete fabrication: "I have never eaten or even nibbled a live hamster, gerbil, guinea pig, mouse, shrew, vole or any other small mammal."
Eventually resulting in 17 libel writs in total, The Sun ran a series of false stories about the pop musician Elton John from 25 February 1987. They began with an invented account of the singer having sexual relationships with rent boys. The singer-songwriter was abroad on the day indicated in the story, as former Sun journalist John Blake, recently poached by the Daily Mirror, soon discovered. After further stories, in September 1987, The Sun accused John of having his Rottweiler guard dogs voice boxes surgically removed. In November, the Daily Mirror found their rival's only source for the rent boy story and he admitted it was a totally fictitious concoction created for money. The inaccurate story about his dogs, actually Alsatians, put pressure on The Sun, and John received £1 million in an out of court settlement, then the largest damages payment in British history. The Sun ran a front-page apology on 12 December 1988, under the banner headline "SORRY, ELTON". In May 1987 gay men were offered free one-way airline tickets to Norway to leave Britain for good: "Fly Away Gays - And We Will Pay" was the paper's headline. Gay Church of England clergymen were described in one headline in November 1987 as "Pulpit poofs".
Television personality Piers Morgan, a former editor of the Daily Mirror and of The Sun's Bizarre pop column, has said that during the late 1980s, at Kelvin MacKenzie's behest, he was ordered to speculate on the sexuality of male pop stars for a feature headlined "The Poofs of Pop". He also recalls MacKenzie headlining a January 1989 story about the first same-sex kiss on the BBC television soap opera EastEnders "EastBenders", describing the kiss between Colin Russell and Guido Smith as "a homosexual love scene between yuppie poofs ... when millions of children were watching".
On 17 November 1989, The Sun headlined a page 2 news story titled "STRAIGHT SEX CANNOT GIVE YOU AIDS – OFFICIAL." The Sun favourably cited the opinions of Lord Kilbracken, a member of the All Parliamentary Group on AIDS. Lord Kilbracken said that only one person out of the 2,372 individuals with HIV/AIDS mentioned in a specific Department of Health report was not a member of a "high risk group", such as homosexuals and recreational drug users. The Sun also ran an editorial further arguing that "At last the truth can be told... the risk of catching AIDS if you are heterosexual is "statistically invisible". In other words, impossible. So now we know – everything else is homosexual propaganda." Although many other British press services covered Lord Kilbracken's public comments, none of them made the argument that the Sun did in its editorial and none of them presented Lord Kilbracken's ideas without context or criticism.
Critics stated that both The Sun and Lord Kilbracken cherry-picked the results from one specific study while ignoring other data reports on HIV infection and not just AIDS infection, which the critics viewed as unethical politicisation of a medical issue. Lord Kilbracken himself criticised The Sun's editorial and the headline of its news story; he stated that while he thought that gay people were more at risk of developing AIDS it was still wrong to imply that no one else could catch the disease. The Press Council condemned The Sun for committing what it called a "gross distortion". The Sun later ran an apology, which they ran on Page 28. Journalist David Randall argued in the textbook The Universal Journalist that The Sun's story was one of the worst cases of journalistic malpractice in recent history, putting its own readers in harm's way.
Under a front page headline "The Truth", the paper printed allegations provided to them that some fans picked the pockets of crushed victims, that others urinated on members of the emergency services as they tried to help and that some even assaulted a police constable "whilst he was administering the kiss of life to a patient." Despite the headline, written by Kelvin MacKenzie, the story was based on allegations either by unnamed and unattributable sources, or hearsay accounts of what named individuals had said – a fact made clear to MacKenzie by Harry Arnold, the reporter who wrote the story.
The front page caused outrage in Liverpool, where the paper lost more than three-quarters of its estimated 55,000 daily sales and still sells poorly in the city more than 25 years later (around 12,000). It is unavailable in many parts of the city, as many newsagents refuse to stock it. It was revealed in a documentary called Alexei Sayle's Liverpool, aired in September 2008, that many Liverpudlians will not even take the newspaper for free, and those who do may simply burn or tear it up. Liverpudlians refer to the paper as 'The Scum' with campaigners believing it handicapped their fight for justice.
On 7 July 2004, in response to verbal attacks in Liverpool on Wayne Rooney, just before his transfer from Everton to Manchester United, who had sold his life story to The Sun, the paper devoted a full-page editorial to an apology for the "awful error" of its Hillsborough coverage and argued that Rooney (who was still only three years old at the time of Hillsborough) should not be punished for its "past sins". In January 2005, The Sun's managing editor Graham Dudman admitting the Hillsborough coverage was "the worst mistake in our history", added: "What we did was a terrible mistake. It was a terrible, insensitive, horrible article, with a dreadful headline; but what we'd also say is: we have apologised for it, and the entire senior team here now is completely different from the team that put the paper out in 1989."
The Sun remained loyal to Thatcher right up to her resignation in November 1990, despite the party's fall in popularity over the previous year following the introduction of the Poll tax (officially known as the Community Charge). This change to the way local government is funded was vociferously supported by the newspaper, despite widespread opposition, (some from Conservative MPs), which is seen as having contributed to Thatcher's own downfall. The tax was quickly repealed by her successor John Major, whom The Sun initially supported enthusiastically, believing he was a radical Thatcherite – despite the economy having entered recession at this time.
Despite its initial opposition to the closures, until 1997, the newspaper repeatedly called for the implementation of further Thatcherite policies, such as Royal Mail privatisation,[verification needed] and social security cutbacks, with leaders such as "Peter Lilley is right, we can't carry on like this",[verification needed] The paper showed hostility to the EU and approval of public spending cuts, tax cuts, and promotion of right-wing ministers to the cabinet, with leaders such as "More of the Redwood, not Deadwood".
The Sun switched support to the Labour party on 18 March 1997, six weeks before the General Election victory which saw the New Labour leader Tony Blair become Prime Minister with a large parliamentary majority, despite the paper having attacked Blair and New Labour up to a month earlier. Its front page headline read THE SUN BACKS BLAIR and its front page editorial made clear that while it still opposed some New Labour policies, such as the Minimum Wage and Devolution, it believed Blair to be "the breath of fresh air this great country needs". John Major's Conservatives, it said, were "tired, divided and rudderless". Blair, who had radically altered his party's image and policies, noting the influence the paper could have over its readers' political thinking, had courted it (and Murdoch) for some time by granting exclusive interviews and writing columns.
In exchange for Rupert Murdoch's support, Blair agreed not to join the European Exchange Rate Mechanism – which John Major had withdrawn the country from in September 1992 after barely two years. Cabinet Minister Peter Mandelson was "outed" by Matthew Parris (a former Sun columnist) on BBC TV's Newsnight in November 1998. Misjudging public response, The Sun's editor David Yelland demanded to know in a front page editorial whether Britain was governed by a "gay mafia" of a "closed world of men with a mutual self-interest". Three days later the paper apologised in another editorial which said The Sun would never again reveal a person's sexuality unless it could be defended on the grounds of "overwhelming public interest".
In 2003 the paper was accused of racism by the Government over its criticisms of what it perceived as the "open door" policy on immigration. The attacks came from the Prime Minister's press spokesman Alastair Campbell and the Home Secretary David Blunkett (later a Sun columnist). The paper rebutted the claim, believing that it was not racist to suggest that a "tide" of unchecked illegal immigrants was increasing the risk of terrorist attacks and infectious diseases. It did not help its argument by publishing a front page story on 4 July 2003, under the headline "Swan Bake", which claimed that asylum seekers were slaughtering and eating swans. It later proved to have no basis in fact. Subsequently The Sun published a follow-up headlined "Now they're after our fish!". Following a Press Complaints Commission adjudication a "clarification" was eventually printed, on page 41. In 2005 The Sun published photographs of Prince Harry sporting a Nazi costume to a fancy dress party. The photographs caused outrage across the world and Clarence House was forced to issue a statement in response apologising for any offence or embarrassment caused.
Despite being a persistent critic of some of the government's policies, the paper supported Labour in both subsequent elections the party won. For the 2005 general election, The Sun backed Blair and Labour for a third consecutive election win and vowed to give him "one last chance" to fulfil his promises, despite berating him for several weaknesses including a failure to control immigration. However, it did speak of its hope that the Conservatives (led by Michael Howard) would one day be fit for a return to government. This election (Blair had declared it would be his last as prime minister) resulted in Labour's third successive win but with a much reduced majority.
On 22 September 2003 the newspaper appeared to misjudge the public mood surrounding mental health, as well as its affection for former world heavyweight champion boxer Frank Bruno, who had been admitted to hospital, when the headline "Bonkers Bruno Locked Up" appeared on the front page of early editions. The adverse reaction, once the paper had hit the streets on the evening of 21 September, led to the headline being changed for the paper's second edition to the more sympathetic "Sad Bruno In Mental Home".
The Sun has been openly antagonistic towards other European nations, particularly the French and Germans. During the 1980s and 1990s, the nationalities were routinely described in copy and headlines as "frogs", "krauts" or "hun". As the paper is opposed to the EU it has referred to foreign leaders who it deemed hostile to the UK in unflattering terms. Former President Jacques Chirac of France, for instance, was branded "le Worm". An unflattering picture of German chancellor Angela Merkel, taken from the rear, bore the headline "I'm Big in the Bumdestag" (17 April 2006).
On 7 January 2009, The Sun ran an exclusive front page story claiming that participants in a discussion on Ummah.com, a British Muslim internet forum, had made a "hate hit list" of British Jews to be targeted by extremists over the Gaza War. It was claimed that "Those listed [on the forum] should treat it very seriously. Expect a hate campaign and intimidation by 20 or 30 thugs." The UK magazine Private Eye claimed that Glen Jenvey, a man quoted by The Sun as a terrorism expert, who had been posting to the forum under the pseudonym "Abuislam", was the only forum member promoting a hate campaign while other members promoted peaceful advocacy, such as writing 'polite letters'. The story has since been removed from The Sun's website following complaints to the UK's Press Complaints Commission.
On 9 December 2010, The Sun published a front-page story claiming that terrorist group Al-Qaeda had threatened a terrorist attack on Granada Television in Manchester to disrupt the episode of the soap opera Coronation Street to be transmitted live that evening. The paper cited unnamed sources, claiming "cops are throwing a ring of steel around tonight's live episode of Coronation Street over fears it has been targeted by Al-Qaeda." Later that morning, however, Greater Manchester Police categorically denied having "been made aware of any threat from Al-Qaeda or any other proscribed organisation." The Sun published a small correction on 28 December, admitting "that while cast and crew were subject to full body searches, there was no specific threat from Al-Qaeda as we reported." The apology had been negotiated by the Press Complaints Commission. For the day following the 2011 Norway attacks The Sun produced an early edition blaming the massacre on al-Qaeda. Later the perpetrator was revealed to be Anders Behring Breivik, a Norwegian nationalist.
In January 2008 the Wapping presses printed The Sun for the last time and London printing was transferred to Waltham Cross in the Borough of Broxbourne in Hertfordshire, where News International had built what is claimed to be the largest printing centre in Europe with 12 presses. The site also produces The Times and Sunday Times, Daily Telegraph and Sunday Telegraph, Wall Street Journal Europe (also now a Murdoch newspaper), London's Evening Standard and local papers. Northern printing had earlier been switched to a new plant at Knowsley on Merseyside and the Scottish Sun to another new plant at Motherwell near Glasgow. The three print centres represent a £600 million investment by NI and allowed all the titles to be produced with every page in full colour from 2008. The Waltham Cross plant is capable of producing one million copies an hour of a 120-page tabloid newspaper.
Politically, the paper's stance was less clear under Prime Minister Gordon Brown who succeeded Blair in June 2007. Its editorials were critical of many of Brown's policies and often more supportive of those of Conservative leader David Cameron. Rupert Murdoch, head of The Sun's parent company News Corporation, speaking at a 2007 meeting with the House of Lords Select Committee on Communications, which was investigating media ownership and the news, said that he acts as a "traditional proprietor". This means he exercises editorial control on major issues such as which political party to back in a general election or which policy to adopt on Europe.
During the campaign for the United Kingdom general election, 2010, The Independent ran ads declaring that "Rupert Murdoch won't decide this election – you will." In response James Murdoch and Rebekah Wade "appeared unannounced and uninvited on the editorial floor" of the Independent, and had an energetic conversation with its editor Simon Kelner. Several days later the Independent reported The Sun's failure to report its own YouGov poll result which said that "if people thought Mr Clegg's party had a significant chance of winning the election" the Liberal Democrats would win 49% of the vote, and with it a landslide majority.
On election day (6 May 2010), The Sun urged its readers to vote for David Cameron's "modern and positive" Conservatives in order to save Britain from "disaster" which the paper thought the country would face if the Labour government was re-elected. The election ended in the first hung parliament after an election for 36 years, with the Tories gaining the most seats and votes but being 20 seats short of an overall majority. They finally came to power on 11 May when Gordon Brown stepped down as prime minister, paving the way for David Cameron to become prime minister by forming a coalition with the Liberal Democrats.
On 28 January 2012, police arrested four current and former staff members of The Sun, as part of a probe in which journalists paid police officers for information; a police officer was also arrested in the probe. The Sun staffers arrested were crime editor Mike Sullivan, head of news Chris Pharo, former deputy editor Fergus Shanahan, and former managing editor Graham Dudman, who since became a columnist and media writer. All five arrested were held on suspicion of corruption. Police also searched the offices of News International, the publishers of The Sun, as part of a continuing investigation into the News of the World scandal.
The main party leaders, David Cameron, Nick Clegg and Ed Miliband, were all depicted holding a copy of the special issue in publicity material. Miliband's decision to pose with a copy of The Sun received a strong response. Organisations representing the relatives of Hillsborough victims described Miliband's action as an "absolute disgrace" and he faced criticism too from Liverpool Labour MPs and the city's Labour Mayor, Joe Anderson. A statement was issued on 13 June explaining that Miliband "was promoting England's bid to win the World Cup", although "he understands the anger that is felt towards the Sun over Hillsborough by many people in Merseyside and he is sorry to those who feel offended."
On 2 June 2013, The Sun on Sunday ran a front page story on singer-songwriter Tulisa Contostavlos. The front page read: "Tulisa's cocaine deal shame"; this story was written by The Sun On Sunday's undercover reporter Mahzer Mahmood, who had previously worked for the News of the World. It was claimed that Tulisa introduced three film producers (actually Mahmood and two other Sun journalists) to a drug dealer and set up a £800 deal. The subterfuge involved conning the singer into believing that she was being considered for a role in an £8 million Bollywood film.
At her subsequent trial, the case against Tulisa collapsed at Southwark Crown Court in July 2014, with the judge commenting that there were "strong grounds" to believe that Mahmood had lied at a pre-trial hearing and tried to manipulate evidence against the co-defendant Tulisa. Tulisa was cleared of supplying Class A drugs. After these events, The Sun released a statement saying that the newspaper "takes the Judge's remarks very seriously. Mahmood has been suspended pending an immediate internal investigation."
In October 2014, the trial of six senior staff and journalists at The Sun newspaper began. All six were charged with conspiring to commit misconduct in a public office. They included The Sun's head of news Chris Pharo, who faced six charges, while ex-managing editor Graham Dudman and ex-Sun deputy news editor Ben O'Driscoll were accused of four charges each. Thames Valley district reporter Jamie Pyatt and picture editor John Edwards were charged with three counts each, while ex-reporter John Troup was accused of two counts. The trial related to illegal payments allegedly made to public officials, with prosecutors saying the men conspired to pay officials from 2002–11, including police, prison officers and soldiers. They were accused of buying confidential information about the Royal Family, public figures and prison inmates. They all denied the charges. On 16 January 2015, Troup and Edwards were cleared by the jury of all charges against them. The jury also partially cleared O'Driscoll and Dudman but continued deliberating over other counts faced by them, as well as the charges against Pharo and Pyatt. On 21 January 2015, the jury told the court that it was unable to reach unanimous verdicts on any of the outstanding charges and was told by the judge, Richard Marks, that he would accept majority verdicts. Shortly afterwards, one of the jurors sent a note to the judge and was discharged. The judge told the remaining 11 jurors that their colleague had been "feeling unwell and feeling under a great deal of pressure and stress from the situation you are in", and that under the circumstances he was prepared to accept majority verdicts of "11 to zero or 10 to 1". On 22 January 2015, the jury was discharged after failing to reach verdicts on the outstanding charges. The Crown Prosecution Service (CPS) announced that it would seek a retrial.
On 6 February 2015, it was announced that Judge Richard Marks is to be replaced by Judge Charles Wide at the retrial. Two days earlier, Marks had emailed counsel for the defendants telling them: "It has been decided (not by me but by my elders and betters) that I am not going to be doing the retrial". Reporting the decision in UK newspaper The Guardian, Lisa O’Carroll wrote: "Wide is the only judge so far to have presided in a case which has seen a conviction of a journalist in relation to allegations of unlawful payments to public officials for stories. The journalist, who cannot be named for legal reasons, is appealing the verdict". Defence counsel for the four journalists threatened to take the decision to judicial review, with the barrister representing Pharo, Nigel Rumfitt QC, saying: "The way this has come about gives rise to the impression that something has been going on behind the scenes which should not have been going on behind the scenes and which should have been dealt with transparently". He added that the defendants were "extremely concerned" and "entitled" to know why Marks was being replaced by Wide.
On 22 May 2015, Sun reporter Anthony France was found guilty of aiding and abetting misconduct in a public office between 2008 and 2011. France’s trial followed the London Metropolitan Police's Operation Elveden, an ongoing investigation into alleged payments to police and officials in exchange for information. He had paid a total of more than £22,000 to PC Timothy Edwards, an anti-terrorism police officer based at Heathrow Airport. The police officer had already pleaded guilty to misconduct in a public office and given a two-year gaol sentence in 2014, but the jury in France’s trial was not informed of this. Following the passing of the guilty verdict, the officer leading Operation Elveden, Detective Chief Superintendent Gordon Briggs said France and Edwards had been in a "long-term, corrupt relationship".
The BBC reported that France was the first journalist to face trial and be convicted under Operation Elveden since the Crown Prosecution Service (CPS) had revised its guidance in April 2015 so that prosecutions would only be brought against journalists who had made payments to police officers over a period of time. As a result of the change in the CPS’ policy, charges against several journalists who had made payments to other types of public officials – including civil servants, health workers and prison staff - had been dropped. In July 2015, Private Eye magazine reported that at a costs hearing at the Old Bailey The Sun's parent company had refused to pay for the prosecution costs relating to France’s trial, leading the presiding judge to express his "considerable disappointment" at this state of affairs. Judge Timothy Pontius said in court that France’s illegal actions had been part of a "clearly recognised procedure at The Sun", adding that, "There can be no doubt that News International bears some measure of moral responsibility if not legal culpability for the acts of the defendant". The Private Eye report noted that despite this The Sun's parent organisation was "considering disciplinary actions" against France whilst at the same time it was also preparing to bring a case to the Investigatory Powers Tribunal against the London Metropolitan Police Service for its actions relating to him and two other journalists.
In August 2013, The Irish Sun ended the practice of featuring topless models on Page 3. The main newspaper was reported to have followed in 2015 with the edition of 16 January supposedly the last to carry such photographs after a report in The Times made such an assertion. After substantial coverage in the media about an alleged change in editorial policy, Page 3 returned to its usual format on 22 January 2015. A few hours before the issue was published, the Head of PR at the newspaper said the reputed end of Page 3 had been "speculation" only.
On 17 April 2015, The Sun's columnist Katie Hopkins called migrants to Britain "cockroaches" and "feral humans" and said they were "spreading like the norovirus". Her remarks were condemned by the United Nations High Commission for Human Rights. In a statement released on 24 April 2015, High Commissioner Zeid Ra'ad Al Hussein stated that Hopkins' used "language very similar to that employed by Rwanda's Kangura newspaper and Radio Mille Collines during the run up to the 1994 genocide", and noted that both media organizations were subsequently convicted by an international tribunal of public incitement to commit genocide.
Hopkins' column also drew criticism on Twitter, including from Russell Brand, to whom Hopkins responded by accusing Brand's "champagne socialist humanity" of neglecting taxpayers. Simon Usborne, writing in The Independent, compared her use of the word "cockroach" to previous uses by the Nazis and just before the Rwandan Genocide by its perpetrators. He suspected that if any other contributor had written the piece it would not have been published and questioned her continued employment by the newspaper. Zoe Williams commented in The Guardian: "It is no joke when people start talking like this. We are not 'giving her what she wants' when we make manifest our disgust. It is not a free speech issue. I’m not saying gag her: I’m saying fight her".
On 9 March 2016, The Sun's front page proclaimed that Queen Elizabeth II was backing "Brexit", a common term for a British withdrawal from the European Union. It claimed that in 2011 at Windsor Castle, while having lunch with Deputy Prime Minister Nick Clegg, the monarch criticised the union. Clegg denied that the Queen made such a statement, and a Buckingham Palace spokesperson confirmed that a complaint had been made to the Independent Press Standards Organisation over a breach of guidelines relating to accuracy.
Pesticides are substances meant for attracting, seducing, and then destroying any pest. They are a class of biocide. The most common use of pesticides is as plant protection products (also known as crop protection products), which in general protect plants from damaging influences such as weeds, fungi, or insects. This use of pesticides is so common that the term pesticide is often treated as synonymous with plant protection product, although it is in fact a broader term, as pesticides are also used for non-agricultural purposes. The term pesticide includes all of the following: herbicide, insecticide, insect growth regulator, nematicide, termiticide, molluscicide, piscicide, avicide, rodenticide, predacide, bactericide, insect repellent, animal repellent, antimicrobial, fungicide, disinfectant (antimicrobial), and sanitizer.
In general, a pesticide is a chemical or biological agent (such as a virus, bacterium, antimicrobial, or disinfectant) that deters, incapacitates, kills, or otherwise discourages pests. Target pests can include insects, plant pathogens, weeds, mollusks, birds, mammals, fish, nematodes (roundworms), and microbes that destroy property, cause nuisance, or spread disease, or are disease vectors. Although pesticides have benefits, some also have drawbacks, such as potential toxicity to humans and other species. According to the Stockholm Convention on Persistent Organic Pollutants, 9 of the 12 most dangerous and persistent organic chemicals are organochlorine pesticides.
Pesticides can be classified by target organism (e.g., herbicides, insecticides, fungicides, rodenticides, and pediculicides - see table), chemical structure (e.g., organic, inorganic, synthetic, or biological (biopesticide), although the distinction can sometimes blur), and physical state (e.g. gaseous (fumigant)). Biopesticides include microbial pesticides and biochemical pesticides. Plant-derived pesticides, or "botanicals", have been developing quickly. These include the pyrethroids, rotenoids, nicotinoids, and a fourth group that includes strychnine and scilliroside.:15
Many pesticides can be grouped into chemical families. Prominent insecticide families include organochlorines, organophosphates, and carbamates. Organochlorine hydrocarbons (e.g., DDT) could be separated into dichlorodiphenylethanes, cyclodiene compounds, and other related compounds. They operate by disrupting the sodium/potassium balance of the nerve fiber, forcing the nerve to transmit continuously. Their toxicities vary greatly, but they have been phased out because of their persistence and potential to bioaccumulate.:239–240 Organophosphate and carbamates largely replaced organochlorines. Both operate through inhibiting the enzyme acetylcholinesterase, allowing acetylcholine to transfer nerve impulses indefinitely and causing a variety of symptoms such as weakness or paralysis. Organophosphates are quite toxic to vertebrates, and have in some cases been replaced by less toxic carbamates.:136–137 Thiocarbamate and dithiocarbamates are subclasses of carbamates. Prominent families of herbicides include phenoxy and benzoic acid herbicides (e.g. 2,4-D), triazines (e.g., atrazine), ureas (e.g., diuron), and Chloroacetanilides (e.g., alachlor). Phenoxy compounds tend to selectively kill broad-leaf weeds rather than grasses. The phenoxy and benzoic acid herbicides function similar to plant growth hormones, and grow cells without normal cell division, crushing the plant's nutrient transport system.:300 Triazines interfere with photosynthesis.:335 Many commonly used pesticides are not included in these families, including glyphosate.
Pesticides can be classified based upon their biological mechanism function or application method. Most pesticides work by poisoning pests. A systemic pesticide moves inside a plant following absorption by the plant. With insecticides and most fungicides, this movement is usually upward (through the xylem) and outward. Increased efficiency may be a result. Systemic insecticides, which poison pollen and nectar in the flowers[citation needed], may kill bees and other needed pollinators[citation needed].
Pesticides are used to control organisms that are considered to be harmful. For example, they are used to kill mosquitoes that can transmit potentially deadly diseases like West Nile virus, yellow fever, and malaria. They can also kill bees, wasps or ants that can cause allergic reactions. Insecticides can protect animals from illnesses that can be caused by parasites such as fleas. Pesticides can prevent sickness in humans that could be caused by moldy food or diseased produce. Herbicides can be used to clear roadside weeds, trees and brush. They can also kill invasive weeds that may cause environmental damage. Herbicides are commonly applied in ponds and lakes to control algae and plants such as water grasses that can interfere with activities like swimming and fishing and cause the water to look or smell unpleasant. Uncontrolled pests such as termites and mold can damage structures such as houses. Pesticides are used in grocery stores and food storage facilities to manage rodents and insects that infest food such as grain. Each use of a pesticide carries some associated risk. Proper pesticide use decreases these associated risks to a level deemed acceptable by pesticide regulatory agencies such as the United States Environmental Protection Agency (EPA) and the Pest Management Regulatory Agency (PMRA) of Canada.
DDT, sprayed on the walls of houses, is an organochlorine that has been used to fight malaria since the 1950s. Recent policy statements by the World Health Organization have given stronger support to this approach. However, DDT and other organochlorine pesticides have been banned in most countries worldwide because of their persistence in the environment and human toxicity. DDT use is not always effective, as resistance to DDT was identified in Africa as early as 1955, and by 1972 nineteen species of mosquito worldwide were resistant to DDT.
In 2006 and 2007, the world used approximately 2.4 megatonnes (5.3×109 lb) of pesticides, with herbicides constituting the biggest part of the world pesticide use at 40%, followed by insecticides (17%) and fungicides (10%). In 2006 and 2007 the U.S. used approximately 0.5 megatonnes (1.1×109 lb) of pesticides, accounting for 22% of the world total, including 857 million pounds (389 kt) of conventional pesticides, which are used in the agricultural sector (80% of conventional pesticide use) as well as the industrial, commercial, governmental and home & garden sectors.Pesticides are also found in majority of U.S. households with 78 million out of the 105.5 million households indicating that they use some form of pesticide. As of 2007, there were more than 1,055 active ingredients registered as pesticides, which yield over 20,000 pesticide products that are marketed in the United States.
Every dollar ($1) that is spent on pesticides for crops yields four dollars ($4) in crops saved. This means based that, on the amount of money spent per year on pesticides, $10 billion, there is an additional $40 billion savings in crop that would be lost due to damage by insects and weeds. In general, farmers benefit from having an increase in crop yield and from being able to grow a variety of crops throughout the year. Consumers of agricultural products also benefit from being able to afford the vast quantities of produce available year-round. The general public also benefits from the use of pesticides for the control of insect-borne diseases and illnesses, such as malaria. The use of pesticides creates a large job market within the agrichemical sector.
Pesticides may cause acute and delayed health effects in people who are exposed. Pesticide exposure can cause a variety of adverse health effects, ranging from simple irritation of the skin and eyes to more severe effects such as affecting the nervous system, mimicking hormones causing reproductive problems, and also causing cancer. A 2007 systematic review found that "most studies on non-Hodgkin lymphoma and leukemia showed positive associations with pesticide exposure" and thus concluded that cosmetic use of pesticides should be decreased. There is substantial evidence of associations between organophosphate insecticide exposures and neurobehavioral alterations. Limited evidence also exists for other negative outcomes from pesticide exposure including neurological, birth defects, fetal death,
The World Health Organization and the UN Environment Programme estimate that each year, 3 million workers in agriculture in the developing world experience severe poisoning from pesticides, about 18,000 of whom die. Owing to inadequate regulation and safety precautions, 99% of pesticide related deaths occur in developing countries that account for only 25% of pesticide usage. According to one study, as many as 25 million workers in developing countries may suffer mild pesticide poisoning yearly. There are several careers aside from agriculture that may also put individuals at risk of health effects from pesticide exposure including pet groomers, groundskeepers, and fumigators.
Pesticide use raises a number of environmental concerns. Over 98% of sprayed insecticides and 95% of herbicides reach a destination other than their target species, including non-target species, air, water and soil. Pesticide drift occurs when pesticides suspended in the air as particles are carried by wind to other areas, potentially contaminating them. Pesticides are one of the causes of water pollution, and some pesticides are persistent organic pollutants and contribute to soil contamination.
Since chlorinated hydrocarbon pesticides dissolve in fats and are not excreted, organisms tend to retain them almost indefinitely. Biological magnification is the process whereby these chlorinated hydrocarbons (pesticides) are more concentrated at each level of the food chain. Among marine animals, pesticide concentrations are higher in carnivorous fishes, and even more so in the fish-eating birds and mammals at the top of the ecological pyramid. Global distillation is the process whereby pesticides are transported from warmer to colder regions of the Earth, in particular the Poles and mountain tops. Pesticides that evaporate into the atmosphere at relatively high temperature can be carried considerable distances (thousands of kilometers) by the wind to an area of lower temperature, where they condense and are carried back to the ground in rain or snow.
In order to reduce negative impacts, it is desirable that pesticides be degradable or at least quickly deactivated in the environment. Such loss of activity or toxicity of pesticides is due to both innate chemical properties of the compounds and environmental processes or conditions. For example, the presence of halogens within a chemical structure often slows down degradation in an aerobic environment. Adsorption to soil may retard pesticide movement, but also may reduce bioavailability to microbial degraders.
Alternatives to pesticides are available and include methods of cultivation, use of biological pest controls (such as pheromones and microbial pesticides), genetic engineering, and methods of interfering with insect breeding. Application of composted yard waste has also been used as a way of controlling pests. These methods are becoming increasingly popular and often are safer than traditional chemical pesticides. In addition, EPA is registering reduced-risk conventional pesticides in increasing numbers.
The term "push-pull" was established in 1987 as an approach for integrated pest management (IPM). This strategy uses a mixture of behavior-modifying stimuli to manipulate the distribution and abundance of insects. "Push" means the insects are repelled or deterred away from whatever resource that is being protected. "Pull" means that certain stimuli (semiochemical stimuli, pheromones, food additives, visual stimuli, genetically altered plants, etc.) are used to attract pests to trap crops where they will be killed. There are numerous different components involved in order to implement a Push-Pull Strategy in IPM.
Some evidence shows that alternatives to pesticides can be equally effective as the use of chemicals. For example, Sweden has halved its use of pesticides with hardly any reduction in crops.[unreliable source?] In Indonesia, farmers have reduced pesticide use on rice fields by 65% and experienced a 15% crop increase.[unreliable source?] A study of Maize fields in northern Florida found that the application of composted yard waste with high carbon to nitrogen ratio to agricultural fields was highly effective at reducing the population of plant-parasitic nematodes and increasing crop yield, with yield increases ranging from 10% to 212%; the observed effects were long-term, often not appearing until the third season of the study.
Pesticides are often referred to according to the type of pest they control. Pesticides can also be considered as either biodegradable pesticides, which will be broken down by microbes and other living beings into harmless compounds, or persistent pesticides, which may take months or years before they are broken down: it was the persistence of DDT, for example, which led to its accumulation in the food chain and its killing of birds of prey at the top of the food chain. Another way to think about pesticides is to consider those that are chemical pesticides or are derived from a common source or production method.
The following sulfonylureas have been commercialized for weed control: amidosulfuron, azimsulfuron, bensulfuron-methyl, chlorimuron-ethyl, ethoxysulfuron, flazasulfuron, flupyrsulfuron-methyl-sodium, halosulfuron-methyl, imazosulfuron, nicosulfuron, oxasulfuron, primisulfuron-methyl, pyrazosulfuron-ethyl, rimsulfuron, sulfometuron-methyl Sulfosulfuron, terbacil, bispyribac-sodium, cyclosulfamuron, and pyrithiobac-sodium. Nicosulfuron, triflusulfuron methyl, and chlorsulfuron are broad-spectrum herbicides that kill plants by inhibiting the enzyme acetolactate synthase. In the 1960s, more than 1 kg/ha (0.89 lb/acre) crop protection chemical was typically applied, while sulfonylureates allow as little as 1% as much material to achieve the same effect.
Though pesticide regulations differ from country to country, pesticides, and products on which they were used are traded across international borders. To deal with inconsistencies in regulations among countries, delegates to a conference of the United Nations Food and Agriculture Organization adopted an International Code of Conduct on the Distribution and Use of Pesticides in 1985 to create voluntary standards of pesticide regulation for different countries. The Code was updated in 1998 and 2002. The FAO claims that the code has raised awareness about pesticide hazards and decreased the number of countries without restrictions on pesticide use.
Three other efforts to improve regulation of international pesticide trade are the United Nations London Guidelines for the Exchange of Information on Chemicals in International Trade and the United Nations Codex Alimentarius Commission.[citation needed] The former seeks to implement procedures for ensuring that prior informed consent exists between countries buying and selling pesticides, while the latter seeks to create uniform standards for maximum levels of pesticide residues among participating countries. Both initiatives operate on a voluntary basis.
Pesticides safety education and pesticide applicator regulation are designed to protect the public from pesticide misuse, but do not eliminate all misuse. Reducing the use of pesticides and choosing less toxic pesticides may reduce risks placed on society and the environment from pesticide use. Integrated pest management, the use of multiple approaches to control pests, is becoming widespread and has been used with success in countries such as Indonesia, China, Bangladesh, the U.S., Australia, and Mexico. IPM attempts to recognize the more widespread impacts of an action on an ecosystem, so that natural balances are not upset. New pesticides are being developed, including biological and botanical derivatives and alternatives that are thought to reduce health and environmental risks. In addition, applicators are being encouraged to consider alternative controls and adopt methods that reduce the use of chemical pesticides.
In the United States, the Environmental Protection Agency (EPA) is responsible for regulating pesticides under the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) and the Food Quality Protection Act (FQPA). Studies must be conducted to establish the conditions in which the material is safe to use and the effectiveness against the intended pest(s). The EPA regulates pesticides to ensure that these products do not pose adverse effects to humans or the environment. Pesticides produced before November 1984 continue to be reassessed in order to meet the current scientific and regulatory standards. All registered pesticides are reviewed every 15 years to ensure they meet the proper standards. During the registration process, a label is created. The label contains directions for proper use of the material in addition to safety restrictions. Based on acute toxicity, pesticides are assigned to a Toxicity Class.

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