term
stringlengths 2
121
| overlap
int64 6
281
| setsize
int64 7
499
| score
float64 1.96
10.6
| pval
float64 0
0.05
| edge
stringlengths 41
1.97k
| type
stringclasses 5
values | subtype
stringclasses 24
values | subtype_key
stringclasses 24
values | edge_idxs
stringlengths 11
1.17k
| ann_idxs
stringlengths 19
2.31k
| ann_vals
stringlengths 124
9.94k
| sig_size
int64 2.2k
3.73k
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Lysosomal lumen
| 25
| 36
| 3.867769
| 0.00011
|
Q14108,P61916,P50897,P10253,P38435,P10619,P06280,P07602,P54802,Q8NHP8,Q8IV08,P16278,Q9UM22,Q13510,O00754,P46976,P11117,P04062,P17900,P15586,P13473,O14773,P06865,P08236,O00584
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
130,256,6,144,145,25,156,36,40,44,175,179,53,313,66,331,79,213,89,218,217,121,99,246,249
|
249,66,121,811,213,1422,156,99,36,918,661,246,144,25,79,1584,217,730,218,179,89,145,3391,331,6,40,256,313,130,175,2134,44,381,804,652,53
|
1.3177131892594451,2.8070566341243905,2.0442894948035293,0.3438753282799643,1.4828295622266432,-0.02351528122041195,1.8066716660719826,2.277678317409277,3.495034957042614,0.25317576686812393,0.4785567416325205,1.338473936006947,1.8863625663085712,4.1354813465701925,2.5638146678084146,-0.09381103021537567,1.4623099427802935,0.4114181815276483,1.4623099427802935,1.6457867663301875,2.431035510324411,1.8863625663085712,-1.9788713010588765,1.0232798624432902,5.121449989369716,3.370732425976295,1.296917258531428,1.0869803140135814,1.9852909461843653,1.6861990067024655,-0.30754673593761184,3.281295714487462,0.937812905361756,0.36643501064183787,0.5008477318133796,3.0643705285634333
| 3,430
|
Sphingolipid metabolic process
| 14
| 28
| 3.383591
| 0.000715
|
P17900,P06865,P07602,Q96G23,P50897,Q8NCC3,P27544,O95470,O60512,P16278,P04062,Q13510,Q06136,P06280
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
89,99,36,68,6,108,82,147,150,179,213,313,59,156
|
548,1633,150,147,213,156,99,36,918,179,89,1649,82,532,6,1824,59,617,313,1305,108,68,381,1278,2972,652,1688,1973
|
0.6116509767559337,-0.11734646334023954,1.8465787199040886,1.866485968870282,1.4828295622266432,1.8066716660719826,2.277678317409277,3.495034957042614,0.25317576686812393,1.6457867663301875,2.431035510324411,-0.11734646334023954,2.54492504446314,0.6336831437767028,5.121449989369716,-0.18826843715602568,2.8625913164326255,0.5230949161824157,1.0869803140135814,0.04632210615831087,2.1809317216381077,2.7884960733515816,0.937812905361756,0.06950099771551356,-0.7237852836123975,0.5008477318133796,-0.11734646334023954,-0.23581657417804916
| 3,430
|
Lysosome
| 26
| 50
| 3.358468
| 0.000784
|
Q14108,P61916,P50897,O75503,P10253,Q9Y487,P10619,P06280,P07602,O15118,P54802,Q93050,P16278,Q13510,O00754,Q99523,P11117,P04062,P17900,P15586,P13473,P06865,Q9Y2T2,Q8NCC3,P08236,O14773
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
130,256,6,138,144,24,25,156,36,164,40,45,179,313,66,78,79,213,89,218,217,99,106,108,246,121
|
809,66,2153,121,164,811,1803,138,213,1422,156,99,36,918,246,2107,2785,144,25,79,611,330,217,730,218,179,89,1237,3391,6,40,2167,256,2389,2066,313,130,522,108,1553,45,381,78,2140,652,2032,1511,3135,106,24
|
0.3438753282799643,2.8070566341243905,-0.33156716576876,2.0442894948035293,1.7465774077703615,0.3438753282799643,-0.18826843715602568,1.9260244005596443,1.4828295622266432,-0.02351528122041195,1.8066716660719826,2.277678317409277,3.495034957042614,0.25317576686812393,1.338473936006947,-0.30754673593761184,-0.6242916466860307,1.8863625663085712,4.1354813465701925,2.5638146678084146,0.5230949161824157,1.0232798624432902,1.4623099427802935,0.4114181815276483,1.4623099427802935,1.6457867663301875,2.431035510324411,0.06950099771551356,-1.9788713010588765,5.121449989369716,3.370732425976295,-0.33156716576876,1.296917258531428,-0.42821167915506675,-0.28358176189719153,1.0869803140135814,1.9852909461843653,0.6556730905320322,2.1809317216381077,-0.07032759590587762,3.2093487244594585,0.937812905361756,2.5826783205648556,-0.30754673593761184,0.5008477318133796,-0.25967184066824295,-0.04689579872958434,-0.849577203134417,2.2197146760906703,4.186254663337337
| 3,430
|
Hydrolase activity acting on glycosyl bonds
| 12
| 30
| 3.242201
| 0.001186
|
Q9BTY2,O00754,O60476,P06865,P54802,O75503,P10253,O60502,P16278,P04062,P17900,P06280
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
128,66,196,99,40,138,144,241,179,213,89,156
|
66,2260,196,241,138,213,1422,156,99,918,246,144,2375,2637,179,89,1934,2531,1389,40,1662,2499,1874,1304,3167,2960,381,128,780,2770
|
2.8070566341243905,-0.3797760297676727,1.5849251978248329,1.359199686384635,1.9260244005596443,1.4828295622266432,-0.02351528122041195,1.8066716660719826,2.277678317409277,0.25317576686812393,1.338473936006947,1.8863625663085712,-0.42821167915506675,-0.5503155785430718,1.6457867663301875,2.431035510324411,-0.23581657417804916,-0.5012978577516536,-0.00018569005958125493,3.370732425976295,-0.11734646334023954,-0.4768775233718424,-0.2120155691768394,0.04632210615831087,-0.900350577456945,-0.7237852836123975,0.937812905361756,2.0049867171526095,0.38894919874105743,-0.5995724062727221
| 3,430
|
Sphingolipid metabolism
| 13
| 26
| 3.182907
| 0.001458
|
P17900,P06865,P07602,Q96G23,P27544,O95470,P16278,P04062,Q13510,P10619,Q06136,P06280,P51648
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
89,99,36,68,82,147,179,213,313,25,59,156,223
|
1632,548,1633,811,1638,147,213,156,99,36,918,25,730,179,89,1649,82,223,59,313,68,381,3003,1278,652,1973
|
-0.11734646334023954,0.6116509767559337,-0.11734646334023954,0.3438753282799643,-0.11734646334023954,1.866485968870282,1.4828295622266432,1.8066716660719826,2.277678317409277,3.495034957042614,0.25317576686812393,4.1354813465701925,0.4114181815276483,1.6457867663301875,2.431035510324411,-0.11734646334023954,2.54492504446314,1.4417564181063023,2.8625913164326255,1.0869803140135814,2.7884960733515816,0.937812905361756,-0.7488153183487716,0.06950099771551356,0.5008477318133796,-0.23581657417804916
| 3,430
|
Membrane lipid metabolic process
| 14
| 37
| 3.161726
| 0.001568
|
P17900,P06865,P07602,Q96G23,P50897,Q8NCC3,P27544,O95470,O60512,P16278,P04062,Q13510,Q06136,P06280
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
89,99,36,68,6,108,82,147,150,179,213,313,59,156
|
548,1633,502,150,1805,147,213,1422,156,99,36,918,179,89,1649,82,532,6,1824,59,617,313,1305,3124,108,1007,1962,68,2965,381,2849,1620,1278,2972,652,1688,1973
|
0.6116509767559337,-0.11734646334023954,0.6776210718932071,1.8465787199040886,-0.18826843715602568,1.866485968870282,1.4828295622266432,-0.02351528122041195,1.8066716660719826,2.277678317409277,3.495034957042614,0.25317576686812393,1.6457867663301875,2.431035510324411,-0.11734646334023954,2.54492504446314,0.6336831437767028,5.121449989369716,-0.18826843715602568,2.8625913164326255,0.5230949161824157,1.0869803140135814,0.04632210615831087,-0.849577203134417,2.1809317216381077,0.20754527371745304,-0.23581657417804916,2.7884960733515816,-0.7237852836123975,0.937812905361756,-0.6490720698046804,-0.09381103021537567,0.06950099771551356,-0.7237852836123975,0.5008477318133796,-0.11734646334023954,-0.23581657417804916
| 3,430
|
Hydrolase activity hydrolyzing o glycosyl compounds
| 11
| 23
| 2.955852
| 0.003118
|
Q9BTY2,O00754,O60476,P06865,P54802,P10253,O60502,P16278,P04062,P17900,P06280
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
128,66,196,99,40,144,241,179,213,89,156
|
66,196,241,213,1422,156,99,918,246,144,179,89,1389,40,1662,2499,1874,1304,2960,381,128,780,2770
|
2.8070566341243905,1.5849251978248329,1.359199686384635,1.4828295622266432,-0.02351528122041195,1.8066716660719826,2.277678317409277,0.25317576686812393,1.338473936006947,1.8863625663085712,1.6457867663301875,2.431035510324411,-0.00018569005958125493,3.370732425976295,-0.11734646334023954,-0.4768775233718424,-0.2120155691768394,0.04632210615831087,-0.7237852836123975,0.937812905361756,2.0049867171526095,0.38894919874105743,-0.5995724062727221
| 3,430
|
Receptor
| 13
| 42
| 2.951017
| 0.003167
|
Q14108,P35613,O15118,Q8WTV0,P11717,P24390,Q99523,Q99720,O00264,Q14739,Q9NS69,O43731,P55899
|
Functions
|
Protein Atlas Molecular function
|
protein_atlas_molecular_function
|
130,254,164,71,330,13,78,47,239,50,23,123,287
|
239,1232,2203,164,344,123,728,856,1643,1807,1701,2479,1702,1023,611,330,1064,2267,1237,1107,13,504,254,287,1998,1435,681,130,50,1121,71,1789,544,78,874,47,906,23,3078,1912,584,833
|
1.359199686384635,0.06950099771551356,-0.35564345936189407,1.7465774077703615,0.9806232501634713,2.0246528531620718,0.4114181815276483,0.2986183093020084,-0.11734646334023954,-0.18826843715602568,-0.1409342612489813,-0.4768775233718424,-0.1409342612489813,0.18465877239643577,0.5230949161824157,1.0232798624432902,0.16172434863187643,-0.3797760297676727,0.06950099771551356,0.1387416835614649,4.7179169525566556,0.6776210718932071,1.296917258531428,1.1924031585962547,-0.25967184066824295,-0.02351528122041195,0.45622167162433763,1.9852909461843653,3.1189087835415297,0.1387416835614649,2.6953211040640213,-0.16457479426822091,0.6336831437767028,2.5826783205648556,0.2986183093020084,3.173240775887535,0.2759203789757193,4.236863344428605,-0.7990668710929513,-0.2120155691768394,0.567458949308088,0.3438753282799643
| 3,430
|
Mitochondrial respiratory chain complex assembly
| 15
| 39
| 2.936603
| 0.003318
|
Q15070,O43676,Q96CU9,Q9BSK2,Q9Y6M9,P51970,P03886,Q9H061,Q9Y2R0,Q9P0J0,O43819,O75306,P47985,Q69YU5,Q6DKK2
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
350,35,103,136,373,425,15,16,81,211,360,309,439,30,31
|
698,35,2775,360,2104,309,1187,1920,752,753,1579,1930,610,15,2736,439,425,1394,350,1950,1537,30,31,1167,474,898,2182,103,136,2891,16,1509,3190,721,211,2197,81,546,373
|
0.4338422448747199,3.512707326927762,-0.6242916466860307,0.9592374039290533,-0.30754673593761184,1.0869803140135814,0.09263033605246422,-0.23581657417804916,0.38894919874105743,0.38894919874105743,-0.09381103021537567,-0.23581657417804916,0.5230949161824157,4.652417670407559,-0.5995724062727221,0.8084416390325024,0.8301027868261046,-0.00018569005958125493,0.9806232501634713,-0.23581657417804916,-0.07032759590587762,3.861838008707718,3.7926560390546924,0.1157104547340278,0.7432157338415764,0.2759203789757193,-0.33156716576876,2.239063866307495,1.965565398534416,-0.6739141572295496,4.5040637689029275,-0.04689579872958434,-0.9258372702304992,0.4338422448747199,1.5033154527373318,-0.33156716576876,2.5638146678084146,0.6336831437767028,0.9592374039290533
| 3,430
|
Mitochondrial protein import
| 12
| 36
| 2.883512
| 0.003933
|
Q9Y584,Q9Y5J9,O60830,P21796,Q5JRX3,O43615,O94826,Q9Y5L4,Q9NS69,O14925,Q99595,Q8N4H5
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
96,225,97,3,126,134,233,183,23,122,157,95
|
122,134,97,3231,1335,1578,699,233,2678,491,1290,3085,631,885,3,3111,2643,2164,1157,596,820,1538,126,95,157,3040,1412,23,298,977,2197,546,96,421,225,183
|
2.0442894948035293,1.965565398534416,2.3161817108012213,-1.0284638912585382,0.02309332399172761,-0.09381103021537567,0.4338422448747199,1.400546940102355,-0.5749138732638202,0.6995273401513898,0.04632210615831087,-0.8242894260138783,0.5008477318133796,0.2759203789757193,5.4060543445312685,-0.849577203134417,-0.5503155785430718,-0.33156716576876,0.1157104547340278,0.5452985658990057,0.3438753282799643,-0.07032759590587762,2.0049867171526095,2.35457505060863,1.8066716660719826,-0.7739090091989397,-0.00018569005958125493,4.236863344428605,1.1503444701717498,0.23038416792428346,-0.33156716576876,0.6336831437767028,2.3353920752424693,0.8517239183017473,1.4417564181063023,1.6457867663301875
| 3,430
|
Exopeptidase activity
| 11
| 32
| 2.879119
| 0.003988
|
Q9H3G5,P42785,Q9NZ08,O75844,Q9UIQ6,Q969V3,O75976,Q9HB40,P55786,O14773,P10619
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
98,38,299,139,12,172,142,17,152,121,25
|
121,139,142,728,311,25,2324,3143,2582,1068,38,3322,152,3330,1437,793,845,1889,580,172,2847,1320,3171,98,2303,17,3045,3187,2716,299,12,1628
|
2.0442894948035293,1.9260244005596443,1.906208661011561,0.4114181815276483,1.0869803140135814,4.1354813465701925,-0.4039652952055236,-0.8749307389569164,-0.5257770590663371,0.16172434863187643,3.441890793303961,-1.2371040916101648,1.826640669391119,-1.263513845201833,-0.02351528122041195,0.36643501064183787,0.32126985958171844,-0.2120155691768394,0.567458949308088,1.7063569746264826,-0.6490720698046804,0.04632210615831087,-0.900350577456945,2.3161817108012213,-0.3797760297676727,4.454305506671291,-0.7739090091989397,-0.9258372702304992,-0.5749138732638202,1.1503444701717498,4.766868416503872,-0.09381103021537567
| 3,430
|
Glycosidase
| 11
| 19
| 2.852391
| 0.004339
|
Q9BTY2,O00754,O60476,P06865,P54802,P10253,O60502,P08236,P16278,P04062,P06280
|
Functions
|
Protein Atlas Molecular function
|
protein_atlas_molecular_function
|
128,66,196,99,40,144,241,246,179,213,156
|
66,2260,196,241,213,1422,156,99,918,246,144,179,1389,40,2499,1874,1304,381,128
|
2.8070566341243905,-0.3797760297676727,1.5849251978248329,1.359199686384635,1.4828295622266432,-0.02351528122041195,1.8066716660719826,2.277678317409277,0.25317576686812393,1.338473936006947,1.8863625663085712,1.6457867663301875,-0.00018569005958125493,3.370732425976295,-0.4768775233718424,-0.2120155691768394,0.04632210615831087,0.937812905361756,2.0049867171526095
| 3,430
|
Lytic vacuole organization
| 8
| 24
| 2.808708
| 0.004974
|
Q14108,Q8N511,P50897,P54802,O75503,P10253,P11117,O14773
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
130,67,6,40,138,144,79,121
|
809,121,138,1754,213,918,144,79,482,6,2057,40,2540,1158,130,665,1078,67,1732,2888,3127,2358,1178,1627
|
0.3438753282799643,2.0442894948035293,1.9260244005596443,-0.16457479426822091,1.4828295622266432,0.25317576686812393,1.8863625663085712,2.5638146678084146,0.7213921450541884,5.121449989369716,-0.28358176189719153,3.370732425976295,-0.5012978577516536,0.1157104547340278,1.9852909461843653,0.4785567416325205,0.16172434863187643,2.8070566341243905,-0.1409342612489813,-0.6739141572295496,-0.849577203134417,-0.4039652952055236,0.1157104547340278,-0.09381103021537567
| 3,430
|
Serine hydrolase activity
| 7
| 18
| 2.803145
| 0.005061
|
Q16740,Q9H3G5,P42785,Q9HB40,O14773,P10619,Q5JRX3
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
2,98,38,17,121,25,126
|
121,142,25,2480,2582,814,38,1482,635,704,2,868,1883,126,2505,845,98,17
|
2.0442894948035293,1.906208661011561,4.1354813465701925,-0.4768775233718424,-0.5257770590663371,0.3438753282799643,3.441890793303961,-0.04689579872958434,0.5008477318133796,0.4338422448747199,5.946267218904173,0.2986183093020084,-0.2120155691768394,2.0049867171526095,-0.4768775233718424,0.32126985958171844,2.3161817108012213,4.454305506671291
| 3,430
|
Glycoside hydrolase superfamily [IPR017853]
| 8
| 16
| 2.800781
| 0.005098
|
Q9BTY2,P06865,P54802,P10253,O60502,P04062,P16278,P06280
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
128,99,40,144,241,213,179,156
|
241,213,1422,156,99,918,1988,246,144,179,1389,40,1662,1874,128,804
|
1.359199686384635,1.4828295622266432,-0.02351528122041195,1.8066716660719826,2.277678317409277,0.25317576686812393,-0.25967184066824295,1.338473936006947,1.8863625663085712,1.6457867663301875,-0.00018569005958125493,3.370732425976295,-0.11734646334023954,-0.2120155691768394,2.0049867171526095,0.36643501064183787
| 3,430
|
Glycosaminoglycan metabolism
| 10
| 15
| 2.798418
| 0.005135
|
P06865,P54802,Q7LGA3,O43505,P08236,O60512,P16278,Q96L58,Q8TB61,P15586
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
99,40,171,146,246,150,179,215,92,218
|
261,146,150,787,99,918,246,218,179,40,171,92,215,2421,1465
|
1.2760859545124026,1.866485968870282,1.8465787199040886,0.36643501064183787,2.277678317409277,0.25317576686812393,1.338473936006947,1.4623099427802935,1.6457867663301875,3.370732425976295,1.7063569746264826,2.4119608690616183,1.4828295622266432,-0.42821167915506675,-0.02351528122041195
| 3,430
|
Disproportionate short stature
| 15
| 30
| 2.777757
| 0.005474
|
Q96MF7,Q15392,Q96HY6,P42345,Q9UHX1,Q7LGA3,Q9UBN7,O95613,Q14739,O75718,Q32P28,P16278,Q6DKJ4,P10644,Q9UBM7
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
290,34,294,482,8,171,500,516,50,361,247,179,117,589,154
|
1183,606,3218,952,2630,361,516,589,179,3244,482,1864,1118,1664,1828,50,2957,34,247,117,171,2297,2610,294,290,1909,154,500,8,1467
|
0.09263033605246422,0.5230949161824157,-1.0027041076562464,0.23038416792428346,-0.5503155785430718,0.9592374039290533,0.6556730905320322,0.5452985658990057,1.6457867663301875,-1.0542934068429035,0.7213921450541884,-0.2120155691768394,0.1387416835614649,-0.11734646334023954,-0.18826843715602568,3.1189087835415297,-0.7237852836123975,3.583187167896173,1.338473936006947,2.083474851760708,1.7063569746264826,-0.3797760297676727,-0.5257770590663371,1.171392087430195,1.1924031585962547,-0.2120155691768394,1.826640669391119,0.6995273401513898,5.057543677692156,-0.02351528122041195
| 3,430
|
Predicted secreted proteins
| 22
| 53
| 2.767373
| 0.005651
|
Q9BTY2,Q15165,P61916,P80303,P43490,Q9HB40,Q08431,Q9H9S5,Q9Y287,Q9NZ08,P17931,P05067,Q9UM22,Q8WUJ1,Q9UMX5,P04083,Q08380,P09429,O75718,O00584,Q02818,O94919
|
Functions
|
Protein Atlas Protein class
|
protein_atlas_protein_class
|
128,1,256,9,11,17,404,283,166,299,301,46,53,76,77,83,93,363,361,249,125,374
|
249,1232,550,2477,361,660,374,728,83,46,1758,2105,2864,363,2635,1064,1989,2267,301,3244,2982,1994,11,1865,2058,256,1998,9,125,841,93,404,2282,1252,1,793,3386,1551,76,417,1318,601,2853,128,2661,2303,283,17,299,53,77,166,657
|
1.3177131892594451,0.06950099771551356,0.6116509767559337,-0.4768775233718424,0.9592374039290533,0.4785567416325205,0.937812905361756,0.4114181815276483,2.5260093370892096,3.191306028311356,-0.16457479426822091,-0.30754673593761184,-0.6739141572295496,0.9592374039290533,-0.5503155785430718,0.16172434863187643,-0.25967184066824295,-0.3797760297676727,1.1292601049826305,-1.0542934068429035,-0.7488153183487716,-0.25967184066824295,4.864332563034109,-0.2120155691768394,-0.28358176189719153,1.296917258531428,-0.25967184066824295,4.993390704618005,2.0246528531620718,0.32126985958171844,2.3737307600439475,0.8733052663722602,-0.3797760297676727,0.06950099771551356,6.5440889483340765,0.36643501064183787,-1.8649399009731702,-0.07032759590587762,2.601516115344004,0.8517239183017473,0.04632210615831087,0.5452985658990057,-0.6490720698046804,2.0049867171526095,-0.5503155785430718,-0.3797760297676727,1.213377883648462,4.454305506671291,1.1503444701717498,3.0643705285634333,2.601516115344004,1.7465774077703615,0.5008477318133796
| 3,430
|
Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen
| 10
| 34
| 2.758207
| 0.005812
|
O15460,Q16850,Q8NB78,P13674,P16435,P30519,Q15800,Q6UW02,P09601,Q32P28
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
434,351,135,395,519,14,178,338,20,247
|
2624,1574,434,2976,550,1061,1188,1421,2373,1337,20,395,519,1193,14,1819,1533,2000,734,178,351,247,1723,1667,338,1833,2403,1261,1550,135,1457,1410,1565,2363
|
-0.5503155785430718,-0.09381103021537567,0.8084416390325024,-0.7488153183487716,0.6116509767559337,0.16172434863187643,0.09263033605246422,-0.02351528122041195,-0.42821167915506675,0.02309332399172761,4.337593478683959,0.8948470616767685,0.6556730905320322,0.09263033605246422,4.701566951120029,-0.18826843715602568,-0.07032759590587762,-0.25967184066824295,0.4114181815276483,1.6660089911781828,0.9806232501634713,1.338473936006947,-0.1409342612489813,-0.11734646334023954,1.0019706637911983,-0.18826843715602568,-0.42821167915506675,0.06950099771551356,-0.07032759590587762,1.965565398534416,-0.02351528122041195,-0.00018569005958125493,-0.07032759590587762,-0.4039652952055236
| 3,430
|
Tetrapyrrole binding
| 10
| 18
| 2.749626
| 0.005966
|
Q16850,Q8WUJ1,Q9H7Z7,O00264,P30519,Q6UW02,P09601,O43169,P53701,Q9Y5Z4
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
351,76,143,239,14,338,20,55,276,322
|
239,344,55,1290,20,2212,14,276,351,338,968,76,1213,1456,143,2766,2368,322
|
1.359199686384635,0.9806232501634713,2.9546651894343055,0.04632210615831087,4.337593478683959,-0.35564345936189407,4.701566951120029,1.2343164607296082,0.9806232501634713,1.0019706637911983,0.23038416792428346,2.601516115344004,0.09263033605246422,-0.02351528122041195,1.906208661011561,-0.5995724062727221,-0.4039652952055236,1.0657844750365362
| 3,430
|
Vacuolar lumen
| 30
| 66
| 2.693565
| 0.007069
|
Q9BTY2,Q14108,P61916,P50897,Q9H7Z7,P10253,P38435,P10619,P06280,P07602,P54802,O00560,Q8NHP8,Q8IV08,P16278,Q9UM22,Q13510,Q9Y5Z4,O00754,P46976,P11117,P04062,P17900,Q9BRF8,P15586,P13473,P06865,O00584,P08236,O14773
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
128,130,256,6,143,144,145,25,156,36,40,300,44,175,179,53,313,322,66,331,79,213,89,357,218,217,99,249,246,121
|
300,249,66,121,811,2901,213,1422,156,99,2105,2106,36,918,661,246,144,25,79,1584,2159,217,730,218,179,89,1650,2870,145,3391,331,1940,6,3162,2382,2328,40,2166,2694,256,2589,1434,2915,2448,1824,618,313,130,1776,175,2134,44,580,1500,2022,381,1793,357,128,804,143,3258,652,53,2362,322
|
1.1292601049826305,1.3177131892594451,2.8070566341243905,2.0442894948035293,0.3438753282799643,-0.6988183969795223,1.4828295622266432,-0.02351528122041195,1.8066716660719826,2.277678317409277,-0.30754673593761184,-0.30754673593761184,3.495034957042614,0.25317576686812393,0.4785567416325205,1.338473936006947,1.8863625663085712,4.1354813465701925,2.5638146678084146,-0.09381103021537567,-0.33156716576876,1.4623099427802935,0.4114181815276483,1.4623099427802935,1.6457867663301875,2.431035510324411,-0.11734646334023954,-0.6739141572295496,1.8863625663085712,-1.9788713010588765,1.0232798624432902,-0.23581657417804916,5.121449989369716,-0.900350577456945,-0.42821167915506675,-0.4039652952055236,3.370732425976295,-0.33156716576876,-0.5749138732638202,1.296917258531428,-0.5257770590663371,-0.02351528122041195,-0.6988183969795223,-0.4525156104496164,-0.18826843715602568,0.5230949161824157,1.0869803140135814,1.9852909461843653,-0.16457479426822091,1.6861990067024655,-0.30754673593761184,3.281295714487462,0.567458949308088,-0.04689579872958434,-0.25967184066824295,0.937812905361756,-0.16457479426822091,0.9806232501634713,2.0049867171526095,0.36643501064183787,1.906208661011561,-1.0542934068429035,0.5008477318133796,3.0643705285634333,-0.4039652952055236,1.0657844750365362
| 3,430
|
Respiratory chain
| 13
| 33
| 2.670516
| 0.007573
|
O43676,Q96CU9,Q9Y6M9,O14949,P51970,P00403,P03886,Q9P0J0,O75306,P22695,P47985,Q9UDW1,Q6DKK2
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
35,103,373,243,425,394,15,211,309,274,439,284,31
|
698,2257,243,35,2775,2104,309,1697,1187,1920,753,2780,1579,610,394,15,1290,3204,2578,274,2736,2688,439,3196,425,1950,1537,31,474,103,211,284,373
|
0.4338422448747199,-0.3797760297676727,1.338473936006947,3.512707326927762,-0.6242916466860307,-0.30754673593761184,1.0869803140135814,-0.1409342612489813,0.09263033605246422,-0.23581657417804916,0.38894919874105743,-0.6242916466860307,-0.09381103021537567,0.5230949161824157,0.8948470616767685,4.652417670407559,0.04632210615831087,-0.977013463993979,-0.5257770590663371,1.2343164607296082,-0.5995724062727221,-0.5749138732638202,0.8084416390325024,-0.9513913766449668,0.8301027868261046,-0.23581657417804916,-0.07032759590587762,3.7926560390546924,0.7432157338415764,2.239063866307495,1.5033154527373318,1.213377883648462,0.9592374039290533
| 3,430
|
Ceramide metabolic process
| 10
| 18
| 2.661715
| 0.007774
|
P17900,P06865,Q96G23,Q8NCC3,P27544,O95470,P04062,O60512,Q13510,P06280
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
89,99,68,108,82,147,213,150,313,156
|
548,1633,150,147,213,156,99,918,89,82,532,1824,313,1305,108,68,381,1278
|
0.6116509767559337,-0.11734646334023954,1.8465787199040886,1.866485968870282,1.4828295622266432,1.8066716660719826,2.277678317409277,0.25317576686812393,2.431035510324411,2.54492504446314,0.6336831437767028,-0.18826843715602568,1.0869803140135814,0.04632210615831087,2.1809317216381077,2.7884960733515816,0.937812905361756,0.06950099771551356
| 3,430
|
Metalloprotease
| 9
| 27
| 2.616393
| 0.008886
|
Q99797,Q9NZ08,O75844,Q9UIQ6,O75976,P42892,O95630,P55786,Q5JRX3
|
Functions
|
Protein Atlas Molecular function
|
protein_atlas_molecular_function
|
199,299,139,12,142,49,245,152,126
|
2625,951,1578,139,142,245,311,2324,2267,49,2220,152,126,793,543,1320,1008,199,1175,2303,3045,3187,2716,299,12,1628,948
|
-0.5503155785430718,0.23038416792428346,-0.09381103021537567,1.9260244005596443,1.906208661011561,1.338473936006947,1.0869803140135814,-0.4039652952055236,-0.3797760297676727,3.1189087835415297,-0.35564345936189407,1.826640669391119,2.0049867171526095,0.36643501064183787,0.6336831437767028,0.04632210615831087,0.20754527371745304,1.5849251978248329,0.1157104547340278,-0.3797760297676727,-0.7739090091989397,-0.9258372702304992,-0.5749138732638202,1.1503444701717498,4.766868416503872,-0.09381103021537567,0.25317576686812393
| 3,430
|
Aminoglycan metabolic process
| 7
| 15
| 2.604693
| 0.009196
|
P06865,P54802,Q7LGA3,O43505,P16278,Q96L58,P15586
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
99,40,171,146,179,215,218
|
146,1983,1581,1422,99,918,246,218,179,40,2389,2595,171,215,1465
|
1.866485968870282,-0.25967184066824295,-0.09381103021537567,-0.02351528122041195,2.277678317409277,0.25317576686812393,1.338473936006947,1.4623099427802935,1.6457867663301875,3.370732425976295,-0.42821167915506675,-0.5257770590663371,1.7063569746264826,1.4828295622266432,-0.02351528122041195
| 3,430
|
metalloprotease
| 8
| 27
| 2.590592
| 0.009581
|
Q99797,O75844,Q9UIQ6,P42892,O95630,P22695,P55786,Q5JRX3
|
Functions
|
Panther Protein class
|
panther_protein_class
|
199,139,12,49,245,274,152,126
|
951,1578,139,245,728,2324,2267,274,3143,2688,49,2220,152,1157,126,793,1889,1320,1008,199,1175,3045,2716,299,12,1628,948
|
0.23038416792428346,-0.09381103021537567,1.9260244005596443,1.338473936006947,0.4114181815276483,-0.4039652952055236,-0.3797760297676727,1.2343164607296082,-0.8749307389569164,-0.5749138732638202,3.1189087835415297,-0.35564345936189407,1.826640669391119,0.1157104547340278,2.0049867171526095,0.36643501064183787,-0.2120155691768394,0.04632210615831087,0.20754527371745304,1.5849251978248329,0.1157104547340278,-0.7739090091989397,-0.5749138732638202,1.1503444701717498,4.766868416503872,-0.09381103021537567,0.25317576686812393
| 3,430
|
Biliary tract abnormality
| 9
| 29
| 2.590274
| 0.00959
|
O96028,Q14108,P07602,Q96J02,Q14739,O15078,P09601,P04062,Q9UJW0
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
191,130,36,295,50,304,20,213,321
|
304,811,383,191,954,213,36,20,1989,730,3295,814,1113,1817,1941,1157,1713,2797,130,50,896,1554,295,2145,652,1909,321,2197,3048
|
1.1081387881403877,0.3438753282799643,0.9163495326117879,1.6052450348577447,0.23038416792428346,1.4828295622266432,3.495034957042614,4.337593478683959,-0.25967184066824295,0.4114181815276483,-1.15832093411627,0.3438753282799643,0.1387416835614649,-0.18826843715602568,-0.23581657417804916,0.1157104547340278,-0.1409342612489813,-0.6242916466860307,1.9852909461843653,3.1189087835415297,0.2759203789757193,-0.07032759590587762,1.171392087430195,-0.30754673593761184,0.5008477318133796,-0.2120155691768394,1.0657844750365362,-0.33156716576876,-0.7739090091989397
| 3,430
|
Anion transmembrane transport
| 23
| 40
| 2.565156
| 0.010313
|
P21796,P12235,P51798,Q9H2D1,P45880,Q9UHG3,Q96NB2,Q9Y6M7,Q9Y619,Q4KMQ2,Q9UBX3,P08183,O75746,Q13546,Q8TB61,Q9BQT8,Q14728,P05556,Q8IWT6,P55011,Q9BXP2,Q9Y277,P30825
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
3,631,520,151,26,27,827,835,57,821,189,323,699,706,92,486,866,856,773,495,903,911,504
|
1855,2935,699,1985,1520,2049,856,323,1988,631,885,3,504,26,520,2381,1657,495,1350,1247,706,866,964,1121,821,773,92,827,486,903,151,1903,1326,189,27,977,911,2722,57,835
|
-0.2120155691768394,-0.7237852836123975,0.4338422448747199,-0.25967184066824295,-0.07032759590587762,-0.28358176189719153,0.2986183093020084,1.0445510616836513,-0.25967184066824295,0.5008477318133796,0.2759203789757193,5.4060543445312685,0.6776210718932071,4.1354813465701925,0.6556730905320322,-0.42821167915506675,-0.11734646334023954,0.6995273401513898,0.02309332399172761,0.06950099771551356,0.4338422448747199,0.2986183093020084,0.23038416792428346,0.1387416835614649,0.3438753282799643,0.38894919874105743,2.4119608690616183,0.3438753282799643,0.7213921450541884,0.2759203789757193,1.8465787199040886,-0.2120155691768394,0.04632210615831087,1.6255321690560474,4.118520027903667,0.23038416792428346,0.2759203789757193,-0.5749138732638202,2.8994929547828066,0.3438753282799643
| 3,430
|
Nadh dehydrogenase complex assembly
| 9
| 28
| 2.533858
| 0.011281
|
Q15070,O43676,Q96CU9,Q9Y6M9,P51970,P03886,Q9H061,Q9P0J0,O75306
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
350,35,103,373,425,15,16,211,309
|
698,35,2775,2104,309,1187,1920,753,1579,610,15,2736,425,350,1950,1537,1167,474,898,2182,103,2891,16,1509,721,211,2197,373
|
0.4338422448747199,3.512707326927762,-0.6242916466860307,-0.30754673593761184,1.0869803140135814,0.09263033605246422,-0.23581657417804916,0.38894919874105743,-0.09381103021537567,0.5230949161824157,4.652417670407559,-0.5995724062727221,0.8301027868261046,0.9806232501634713,-0.23581657417804916,-0.07032759590587762,0.1157104547340278,0.7432157338415764,0.2759203789757193,-0.33156716576876,2.239063866307495,-0.6739141572295496,4.5040637689029275,-0.04689579872958434,0.4338422448747199,1.5033154527373318,-0.33156716576876,0.9592374039290533
| 3,430
|
Signal sequence binding
| 9
| 29
| 2.525728
| 0.011546
|
Q9Y584,P52294,O00505,O00629,O94826,P24390,O60684,Q92973,O43731
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
96,255,226,195,233,13,110,182,123
|
1019,226,195,586,123,110,233,13,1427,2690,577,2443,1817,305,255,635,3116,2834,2223,1778,3097,820,1005,182,1676,2413,945,696,96
|
0.18465877239643577,1.4211688103555455,1.5849251978248329,0.5452985658990057,2.0246528531620718,2.122543890584666,1.400546940102355,4.7179169525566556,-0.02351528122041195,-0.5749138732638202,0.567458949308088,-0.4525156104496164,-0.18826843715602568,1.1081387881403877,1.296917258531428,0.5008477318133796,-0.849577203134417,-0.6490720698046804,-0.35564345936189407,-0.16457479426822091,-0.8242894260138783,0.3438753282799643,0.20754527371745304,1.6457867663301875,-0.11734646334023954,-0.42821167915506675,0.25317576686812393,0.45622167162433763,2.3353920752424693
| 3,430
|
Protein insertion into membrane
| 15
| 29
| 2.521574
| 0.011683
|
Q15629,P46379,Q9Y584,Q15070,Q9Y5J9,O43765,O14737,O94826,Q9Y512,Q9Y5L4,Q9P0J0,Q9NS69,Q9Y5J7,P07900,Q07812
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
64,161,96,350,225,627,70,233,546,183,211,23,421,661,617
|
70,811,627,233,661,2687,2944,161,2834,617,1488,350,64,1305,2804,1311,1959,1083,717,1327,23,3259,211,2197,546,96,421,225,183
|
2.6953211040640213,0.3438753282799643,0.5008477318133796,1.400546940102355,0.4785567416325205,-0.5749138732638202,-0.7237852836123975,1.7666401896879766,-0.6490720698046804,0.5230949161824157,-0.04689579872958434,0.9806232501634713,2.825592626630927,0.04632210615831087,-0.6242916466860307,0.04632210615831087,-0.23581657417804916,0.16172434863187643,0.4338422448747199,0.04632210615831087,4.236863344428605,-1.0542934068429035,1.5033154527373318,-0.33156716576876,0.6336831437767028,2.3353920752424693,0.8517239183017473,1.4417564181063023,1.6457867663301875
| 3,430
|
Sensorimotor neuropathy
| 11
| 30
| 2.514858
| 0.011908
|
Q15120,P07602,P40939,Q13217,Q9NSE4,Q92734,P00403,P03886,Q9Y2R0,Q9NR77,O60313
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
415,36,386,618,400,523,394,15,81,60,94
|
915,1633,94,1930,394,15,1423,1106,36,837,2981,1425,386,2444,1941,2166,2646,1870,618,415,932,523,2754,802,60,400,2030,652,81,948
|
0.25317576686812393,-0.11734646334023954,2.35457505060863,-0.23581657417804916,0.8948470616767685,4.652417670407559,-0.02351528122041195,0.1387416835614649,3.495034957042614,0.32126985958171844,-0.7488153183487716,-0.02351528122041195,0.9163495326117879,-0.4525156104496164,-0.23581657417804916,-0.33156716576876,-0.5503155785430718,-0.2120155691768394,0.5230949161824157,0.8517239183017473,0.25317576686812393,0.6556730905320322,-0.5995724062727221,0.36643501064183787,2.8625913164326255,0.8948470616767685,-0.25967184066824295,0.5008477318133796,2.5638146678084146,0.25317576686812393
| 3,430
|
Sphingolipid biosynthetic process
| 6
| 15
| 2.514582
| 0.011917
|
Q96G23,P27544,O95470,P04062,O60512,Q06136
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
68,82,147,213,150,59
|
548,1633,150,147,213,1649,82,1824,59,313,1305,68,1278,1688,1973
|
0.6116509767559337,-0.11734646334023954,1.8465787199040886,1.866485968870282,1.4828295622266432,-0.11734646334023954,2.54492504446314,-0.18826843715602568,2.8625913164326255,1.0869803140135814,0.04632210615831087,2.7884960733515816,0.06950099771551356,-0.11734646334023954,-0.23581657417804916
| 3,430
|
Protein targeting to mitochondrion
| 16
| 46
| 2.505275
| 0.012236
|
Q9Y584,Q9Y5J9,O60830,Q5JRX3,O43615,Q99797,O14737,O14925,O94826,Q9P0J0,Q9Y5L4,Q9NS69,P55786,Q9UII2,Q99595,Q8N4H5
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
96,225,97,126,134,199,70,122,233,211,183,23,152,222,157,95
|
2773,70,122,134,97,1578,233,2631,1289,1700,1930,2678,661,3085,3142,1194,2944,263,2792,2380,152,2914,1157,820,2802,1538,1305,126,1607,95,368,559,157,199,649,1412,23,211,3290,222,3284,546,96,421,225,183
|
-0.6242916466860307,2.6953211040640213,2.0442894948035293,1.965565398534416,2.3161817108012213,-0.09381103021537567,1.400546940102355,-0.5503155785430718,0.04632210615831087,-0.1409342612489813,-0.23581657417804916,-0.5749138732638202,0.4785567416325205,-0.8242894260138783,-0.8749307389569164,0.09263033605246422,-0.7237852836123975,1.2760859545124026,-0.6242916466860307,-0.42821167915506675,1.826640669391119,-0.6988183969795223,0.1157104547340278,0.3438753282799643,-0.6242916466860307,-0.07032759590587762,0.04632210615831087,2.0049867171526095,-0.09381103021537567,2.35457505060863,0.9592374039290533,0.6116509767559337,1.8066716660719826,1.5849251978248329,0.5008477318133796,-0.00018569005958125493,4.236863344428605,1.5033154527373318,-1.1322063957742325,1.4623099427802935,-1.1061640452367623,0.6336831437767028,2.3353920752424693,0.8517239183017473,1.4417564181063023,1.6457867663301875
| 3,430
|
Molecular transducer activity
| 7
| 34
| 2.492483
| 0.012685
|
Q15629,Q14108,O15118,Q8WTV0,P11717,Q99523,Q99720
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
64,130,164,71,330,78,47
|
1232,2203,164,344,856,1807,1023,330,1237,1194,2113,3207,1653,1245,1435,681,130,64,1121,1122,1723,71,1789,544,1216,78,47,3201,1414,3078,1052,653,1280,1571
|
0.06950099771551356,-0.35564345936189407,1.7465774077703615,0.9806232501634713,0.2986183093020084,-0.18826843715602568,0.18465877239643577,1.0232798624432902,0.06950099771551356,0.09263033605246422,-0.30754673593761184,-0.977013463993979,-0.11734646334023954,0.06950099771551356,-0.02351528122041195,0.45622167162433763,1.9852909461843653,2.825592626630927,0.1387416835614649,0.1387416835614649,-0.1409342612489813,2.6953211040640213,-0.16457479426822091,0.6336831437767028,0.09263033605246422,2.5826783205648556,3.173240775887535,-0.9513913766449668,-0.00018569005958125493,-0.7990668710929513,0.18465877239643577,0.5008477318133796,0.06950099771551356,-0.07032759590587762
| 3,430
|
Steroid metabolism
| 11
| 28
| 2.48737
| 0.012869
|
Q16850,Q15392,P61916,O15118,O76062,Q06520,Q15800,Q14739,P54646,P04062,Q9UBM7
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
351,34,256,164,69,7,178,50,336,213,154
|
164,587,1421,69,1519,2901,213,1990,2213,857,385,3412,336,256,1868,2591,7,3347,50,3099,34,1880,178,351,2560,154,1800,1376
|
1.7465774077703615,0.5452985658990057,-0.02351528122041195,2.714006070492743,-0.07032759590587762,-0.6988183969795223,1.4828295622266432,-0.25967184066824295,-0.35564345936189407,0.2986183093020084,0.9163495326117879,-2.360290770874015,1.0019706637911983,1.296917258531428,-0.2120155691768394,-0.5257770590663371,5.105496372209571,-1.3431986759033332,3.1189087835415297,-0.8242894260138783,3.583187167896173,-0.2120155691768394,1.6660089911781828,0.9806232501634713,-0.5012978577516536,1.826640669391119,-0.16457479426822091,0.02309332399172761
| 3,430
|
Membrane lipid catabolic process
| 7
| 13
| 2.462728
| 0.013788
|
P17900,P06865,P50897,O95470,P04062,Q13510,P06280
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
89,99,6,147,213,313,156
|
147,213,1422,156,99,918,89,6,1824,313,381,2849,1278
|
1.866485968870282,1.4828295622266432,-0.02351528122041195,1.8066716660719826,2.277678317409277,0.25317576686812393,2.431035510324411,5.121449989369716,-0.18826843715602568,1.0869803140135814,0.937812905361756,-0.6490720698046804,0.06950099771551356
| 3,430
|
Entry into host
| 8
| 34
| 2.450888
| 0.01425
|
Q9BTY2,Q14108,O00505,P35613,Q96J02,O15118,Q8WTV0,P14373
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
128,130,226,254,295,164,71,251
|
2097,226,1232,164,3015,728,856,1643,1807,1337,1988,2479,1702,611,1064,251,2267,2271,1424,254,2053,2443,1998,1301,130,1718,1121,71,1789,295,740,128,1178,332
|
-0.30754673593761184,1.4211688103555455,0.06950099771551356,1.7465774077703615,-0.7739090091989397,0.4114181815276483,0.2986183093020084,-0.11734646334023954,-0.18826843715602568,0.02309332399172761,-0.25967184066824295,-0.4768775233718424,-0.1409342612489813,0.5230949161824157,0.16172434863187643,1.3177131892594451,-0.3797760297676727,-0.3797760297676727,-0.02351528122041195,1.296917258531428,-0.28358176189719153,-0.4525156104496164,-0.25967184066824295,0.04632210615831087,1.9852909461843653,-0.1409342612489813,0.1387416835614649,2.6953211040640213,-0.16457479426822091,1.171392087430195,0.4114181815276483,2.0049867171526095,0.1157104547340278,1.0232798624432902
| 3,430
|
Hormone metabolic process
| 7
| 29
| 2.438184
| 0.014761
|
Q06520,O75844,Q9HB40,P42892,O95470,Q9UBM7,Q14849
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
7,139,17,49,147,154,62
|
1060,139,3417,147,1423,2267,2683,519,1194,234,49,3179,1941,2537,2281,7,62,2453,822,771,1728,2885,2076,2557,2560,17,154,1911,1914
|
0.16172434863187643,1.9260244005596443,-2.729289471050285,1.866485968870282,-0.02351528122041195,-0.3797760297676727,-0.5749138732638202,0.6556730905320322,0.09263033605246422,1.400546940102355,3.1189087835415297,-0.9258372702304992,-0.23581657417804916,-0.5012978577516536,-0.3797760297676727,5.105496372209571,2.8441041534478297,-0.4525156104496164,0.3438753282799643,0.38894919874105743,-0.1409342612489813,-0.6739141572295496,-0.28358176189719153,-0.5012978577516536,-0.5012978577516536,4.454305506671291,1.826640669391119,-0.2120155691768394,-0.2120155691768394
| 3,430
|
Steroid binding
| 9
| 23
| 2.437053
| 0.014808
|
Q14108,P21796,P61916,O15118,O00264,P38435,P04062,P45880,Q14849
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
130,3,256,164,239,145,213,26,62
|
239,164,344,587,1519,213,1423,3018,3,1649,1704,1194,857,145,26,256,130,62,687,2355,2141,514,3377
|
1.359199686384635,1.7465774077703615,0.9806232501634713,0.5452985658990057,-0.07032759590587762,1.4828295622266432,-0.02351528122041195,-0.7739090091989397,5.4060543445312685,-0.11734646334023954,-0.1409342612489813,0.09263033605246422,0.2986183093020084,1.8863625663085712,4.1354813465701925,1.296917258531428,1.9852909461843653,2.8441041534478297,0.45622167162433763,-0.4039652952055236,-0.30754673593761184,0.6776210718932071,-1.6968271446485936
| 3,430
|
Protein transporter activity
| 7
| 15
| 2.435565
| 0.014869
|
Q9Y584,Q9Y5J9,O60830,Q9HD20,Q9NS69,O14925,Q99595
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
96,225,97,105,23,122,157
|
122,97,233,2678,762,2834,1248,820,1890,157,105,23,653,96,225
|
2.0442894948035293,2.3161817108012213,1.400546940102355,-0.5749138732638202,0.38894919874105743,-0.6490720698046804,0.06950099771551356,0.3438753282799643,-0.2120155691768394,1.8066716660719826,2.2197146760906703,4.236863344428605,0.5008477318133796,2.3353920752424693,1.4417564181063023
| 3,430
|
Negative regulation of rna catabolic process
| 14
| 32
| 2.410488
| 0.015931
|
Q9Y2W1,O60506,P98175,Q9H2U1,Q99729,Q14011,P35637,P11940,P07910,O95453,Q14103,Q06787,Q92804,P67809
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
584,292,397,431,430,426,140,518,517,119,443,153,187,252
|
744,292,2861,1518,119,517,518,140,1863,252,397,2063,153,1825,1869,2917,2391,637,426,443,1440,1668,1961,187,1041,430,2759,1220,431,904,1687,584
|
0.38894919874105743,1.171392087430195,-0.6739141572295496,-0.07032759590587762,2.063896781548296,0.6556730905320322,0.6556730905320322,1.9260244005596443,-0.2120155691768394,1.3177131892594451,0.8948470616767685,-0.28358176189719153,1.826640669391119,-0.18826843715602568,-0.2120155691768394,-0.6988183969795223,-0.42821167915506675,0.5008477318133796,0.8301027868261046,0.8084416390325024,-0.02351528122041195,-0.11734646334023954,-0.23581657417804916,1.6255321690560474,0.18465877239643577,0.8301027868261046,-0.5995724062727221,0.09263033605246422,0.8301027868261046,0.2759203789757193,-0.11734646334023954,0.567458949308088
| 3,430
|
Dysostosis multiplex
| 6
| 10
| 2.409669
| 0.015967
|
O00754,P54802,P08236,P16278,P10619,P15586
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
66,40,246,179,25,218
|
66,1422,246,25,218,179,40,1732,381,2770
|
2.8070566341243905,-0.02351528122041195,1.338473936006947,4.1354813465701925,1.4623099427802935,1.6457867663301875,3.370732425976295,-0.1409342612489813,0.937812905361756,-0.5995724062727221
| 3,430
|
Secondary alcohol metabolic process
| 18
| 46
| 2.396055
| 0.016573
|
Q16850,P48735,Q15392,P61916,O15118,O76062,Q06520,Q8WTV0,P05067,Q15800,Q9BQE5,Q14739,P54646,P04062,P48449,Q14849,Q9UBM7,O75874
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
351,129,34,256,164,69,7,71,46,178,19,50,336,213,112,62,154,286
|
164,1284,587,1421,286,69,1519,2901,213,46,3361,1990,519,2213,3384,857,385,2644,112,129,2114,3222,2164,2382,3412,336,2537,256,1868,2591,7,3347,734,50,62,3099,34,1880,178,351,71,3040,19,2141,154,1800
|
1.7465774077703615,0.04632210615831087,0.5452985658990057,-0.02351528122041195,1.1924031585962547,2.714006070492743,-0.07032759590587762,-0.6988183969795223,1.4828295622266432,3.191306028311356,-1.4505344444969863,-0.25967184066824295,0.6556730905320322,-0.35564345936189407,-1.8366930943997668,0.2986183093020084,0.9163495326117879,-0.5503155785430718,2.122543890584666,1.9852909461843653,-0.30754673593761184,-1.0027041076562464,-0.33156716576876,-0.42821167915506675,-2.360290770874015,1.0019706637911983,-0.5012978577516536,1.296917258531428,-0.2120155691768394,-0.5257770590663371,5.105496372209571,-1.3431986759033332,0.4114181815276483,3.1189087835415297,2.8441041534478297,-0.8242894260138783,3.583187167896173,-0.2120155691768394,1.6660089911781828,0.9806232501634713,2.6953211040640213,-0.7739090091989397,4.3877182006716735,-0.30754673593761184,1.826640669391119,-0.16457479426822091
| 3,430
|
Abnormal biliary tract morphology
| 7
| 26
| 2.395608
| 0.016593
|
Q14108,P07602,Q96J02,Q14739,O15078,P09601,P04062
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
130,36,295,50,304,20,213
|
304,811,954,213,36,20,1989,730,3295,814,1113,1817,1941,1157,1713,130,50,896,1554,295,2145,652,1909,321,2197,3048
|
1.1081387881403877,0.3438753282799643,0.23038416792428346,1.4828295622266432,3.495034957042614,4.337593478683959,-0.25967184066824295,0.4114181815276483,-1.15832093411627,0.3438753282799643,0.1387416835614649,-0.18826843715602568,-0.23581657417804916,0.1157104547340278,-0.1409342612489813,1.9852909461843653,3.1189087835415297,0.2759203789757193,-0.07032759590587762,1.171392087430195,-0.30754673593761184,0.5008477318133796,-0.2120155691768394,1.0657844750365362,-0.33156716576876,-0.7739090091989397
| 3,430
|
Proportionate short stature
| 11
| 35
| 2.395358
| 0.016604
|
Q96MF7,Q15392,Q96HY6,Q13535,Q16836,Q14739,P16278,Q96L58,P53701,Q9Y619,P10619
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
290,34,294,348,42,50,179,215,276,57,25
|
3218,2897,2630,25,589,179,2161,1763,2440,3245,2583,1862,1705,2643,386,994,634,276,840,537,348,2498,50,34,2341,42,2958,792,3170,1501,294,215,290,1323,57
|
-1.0027041076562464,-0.6988183969795223,-0.5503155785430718,4.1354813465701925,0.5452985658990057,1.6457867663301875,-0.33156716576876,-0.16457479426822091,-0.4525156104496164,-1.0542934068429035,-0.5257770590663371,-0.2120155691768394,-0.1409342612489813,-0.5503155785430718,0.9163495326117879,0.20754527371745304,0.5008477318133796,1.2343164607296082,0.32126985958171844,0.6336831437767028,0.9806232501634713,-0.4768775233718424,3.1189087835415297,3.583187167896173,-0.4039652952055236,3.3350234117032413,-0.7237852836123975,0.36643501064183787,-0.900350577456945,-0.04689579872958434,1.171392087430195,1.4828295622266432,1.1924031585962547,0.04632210615831087,2.8994929547828066
| 3,430
|
Glycosphingolipid metabolism
| 8
| 16
| 2.392925
| 0.016715
|
P17900,P06865,P07602,P04062,P16278,Q13510,P10619,P06280
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
89,99,36,213,179,313,25,156
|
1632,811,213,156,99,36,918,25,730,179,89,313,381,3003,1278,652
|
-0.11734646334023954,0.3438753282799643,1.4828295622266432,1.8066716660719826,2.277678317409277,3.495034957042614,0.25317576686812393,4.1354813465701925,0.4114181815276483,1.6457867663301875,2.431035510324411,1.0869803140135814,0.937812905361756,-0.7488153183487716,0.06950099771551356,0.5008477318133796
| 3,430
|
Cupped ear
| 6
| 13
| 2.391613
| 0.016775
|
Q15392,P63241,Q01082,P78318,P42892,Q9P2D1
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
34,347,483,462,49,221
|
1473,1759,49,1431,347,462,483,1535,34,498,1607,1734,221
|
-0.04689579872958434,-0.16457479426822091,3.1189087835415297,-0.02351528122041195,0.9806232501634713,0.7649983512811526,0.7213921450541884,-0.07032759590587762,3.583187167896173,0.6995273401513898,-0.09381103021537567,-0.1409342612489813,1.4623099427802935
| 3,430
|
Abnormal chorioretinal morphology
| 13
| 28
| 2.384205
| 0.017116
|
O14936,Q9P2D1,P40939,P40855,Q01082,O60826,Q8NAT1,O43505,O15078,P04439,P53701,Q9Y619,Q9H9S5
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
530,221,386,577,483,107,273,146,304,335,276,57,283
|
530,304,146,2101,107,2726,1921,1931,335,1340,1705,577,386,1817,634,276,483,921,1157,1158,896,3170,273,2607,1732,283,221,57
|
0.6336831437767028,1.1081387881403877,1.866485968870282,-0.30754673593761184,2.1809317216381077,-0.5995724062727221,-0.23581657417804916,-0.23581657417804916,1.0019706637911983,0.02309332399172761,-0.1409342612489813,0.567458949308088,0.9163495326117879,-0.18826843715602568,0.5008477318133796,1.2343164607296082,0.7213921450541884,0.25317576686812393,0.1157104547340278,0.1157104547340278,0.2759203789757193,-0.900350577456945,1.2552190861703458,-0.5257770590663371,-0.1409342612489813,1.213377883648462,1.4623099427802935,2.8994929547828066
| 3,430
|
Calcium-binding protein
| 9
| 21
| 2.379136
| 0.017353
|
Q8IYU8,P80303,P43307,Q9Y376,Q14257,P41208,O43852,Q9BRK5,Q02818
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
296,9,48,148,85,116,184,90,125
|
184,324,2904,2827,116,48,2950,2385,9,125,85,1201,2959,1546,296,2549,3106,601,1217,90,148
|
1.6255321690560474,1.0445510616836513,-0.6988183969795223,-0.6490720698046804,2.083474851760708,3.155152877745957,-0.7237852836123975,-0.42821167915506675,4.993390704618005,2.0246528531620718,2.4880992123030645,0.09263033605246422,-0.7237852836123975,-0.07032759590587762,1.1503444701717498,-0.5012978577516536,-0.8242894260138783,0.5452985658990057,0.09263033605246422,2.431035510324411,1.866485968870282
| 3,430
|
Abnormality of head blood vessel
| 7
| 25
| 2.366707
| 0.017947
|
P17900,P06865,P07602,P03886,P16278,Q13510,P10619
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
89,99,36,15,179,313,25
|
3012,1853,1750,1576,15,99,36,918,25,2682,179,89,2824,1586,2828,994,2275,1660,313,707,1894,381,652,2089,657
|
-0.7739090091989397,-0.2120155691768394,-0.16457479426822091,-0.09381103021537567,4.652417670407559,2.277678317409277,3.495034957042614,0.25317576686812393,4.1354813465701925,-0.5749138732638202,1.6457867663301875,2.431035510324411,-0.6490720698046804,-0.09381103021537567,-0.6490720698046804,0.20754527371745304,-0.3797760297676727,-0.11734646334023954,1.0869803140135814,0.4338422448747199,-0.2120155691768394,0.937812905361756,0.5008477318133796,-0.28358176189719153,0.5008477318133796
| 3,430
|
Sterol metabolic process
| 16
| 42
| 2.364618
| 0.018049
|
Q16850,Q15392,P61916,O15118,O76062,Q06520,Q8WTV0,P05067,Q15800,Q9BQE5,Q14739,P54646,P04062,P48449,Q9UBM7,Q14849
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
351,34,256,164,69,7,71,46,178,19,50,336,213,112,154,62
|
164,587,1421,69,1519,2901,213,46,3361,1990,519,2213,3384,857,385,3391,2644,112,2114,2382,3412,336,2537,256,1868,2591,7,3347,734,50,62,3099,34,1880,178,351,71,19,2141,154,1800,1376
|
1.7465774077703615,0.5452985658990057,-0.02351528122041195,2.714006070492743,-0.07032759590587762,-0.6988183969795223,1.4828295622266432,3.191306028311356,-1.4505344444969863,-0.25967184066824295,0.6556730905320322,-0.35564345936189407,-1.8366930943997668,0.2986183093020084,0.9163495326117879,-1.9788713010588765,-0.5503155785430718,2.122543890584666,-0.30754673593761184,-0.42821167915506675,-2.360290770874015,1.0019706637911983,-0.5012978577516536,1.296917258531428,-0.2120155691768394,-0.5257770590663371,5.105496372209571,-1.3431986759033332,0.4114181815276483,3.1189087835415297,2.8441041534478297,-0.8242894260138783,3.583187167896173,-0.2120155691768394,1.6660089911781828,0.9806232501634713,2.6953211040640213,4.3877182006716735,-0.30754673593761184,1.826640669391119,-0.16457479426822091,0.02309332399172761
| 3,430
|
Endocytic vesicle membrane
| 11
| 40
| 2.360826
| 0.018234
|
Q15907,Q14108,Q5T9L3,Q8WTV0,Q03518,P11717,P01889,Q93050,P04439,Q9Y487,P13473
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
389,130,230,71,74,330,329,45,335,24,217
|
985,1577,1925,1581,329,728,335,402,611,330,632,217,1237,2904,1027,2057,1115,1344,2538,2386,2167,2223,2389,921,74,1073,681,2498,2989,130,1598,2287,389,230,71,45,1676,1322,2974,24
|
0.20754527371745304,-0.09381103021537567,-0.23581657417804916,-0.09381103021537567,1.0232798624432902,0.4114181815276483,1.0019706637911983,0.8733052663722602,0.5230949161824157,1.0232798624432902,0.5008477318133796,1.4623099427802935,0.06950099771551356,-0.6988183969795223,0.18465877239643577,-0.28358176189719153,0.1387416835614649,0.02309332399172761,-0.5012978577516536,-0.42821167915506675,-0.33156716576876,-0.35564345936189407,-0.42821167915506675,0.25317576686812393,2.620328163937606,0.16172434863187643,0.45622167162433763,-0.4768775233718424,-0.7488153183487716,1.9852909461843653,-0.09381103021537567,-0.3797760297676727,0.9163495326117879,1.4211688103555455,2.6953211040640213,3.2093487244594585,-0.11734646334023954,0.04632210615831087,-0.7237852836123975,4.186254663337337
| 3,430
|
Mitochondrial transmembrane transport
| 18
| 51
| 2.336094
| 0.019486
|
O60830,P56385,P21796,Q9BQT8,O43615,O95202,Q9BSK2,Q8IYU8,O94826,O43772,P23786,P24539,O75964,Q6P4A7,Q9H2D1,Q9Y619,O14925,Q99595
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
97,440,3,486,134,383,136,296,233,109,270,494,52,277,151,57,122,157
|
122,134,109,97,2317,1578,699,2262,52,233,383,1520,1930,2678,2049,491,3085,631,885,3,270,494,3111,1152,2831,2218,2381,3266,440,1350,820,2227,1538,277,296,899,1893,1083,827,157,486,136,151,1903,1326,1412,1092,977,697,948,57
|
2.0442894948035293,1.965565398534416,2.1420351304999743,2.3161817108012213,-0.4039652952055236,-0.09381103021537567,0.4338422448747199,-0.3797760297676727,3.1007524055777593,1.400546940102355,0.9163495326117879,-0.07032759590587762,-0.23581657417804916,-0.5749138732638202,-0.28358176189719153,0.6995273401513898,-0.8242894260138783,0.5008477318133796,0.2759203789757193,5.4060543445312685,1.2552190861703458,0.6995273401513898,-0.849577203134417,0.1157104547340278,-0.6490720698046804,-0.35564345936189407,-0.42821167915506675,-1.0801932550383022,0.8084416390325024,0.02309332399172761,0.3438753282799643,-0.35564345936189407,-0.07032759590587762,1.2343164607296082,1.1503444701717498,0.2759203789757193,-0.2120155691768394,0.16172434863187643,0.3438753282799643,1.8066716660719826,0.7213921450541884,1.965565398534416,1.8465787199040886,-0.2120155691768394,0.04632210615831087,-0.00018569005958125493,0.16172434863187643,0.23038416792428346,0.45622167162433763,0.25317576686812393,2.8994929547828066
| 3,430
|
Vertebral segmentation defect
| 9
| 31
| 2.334921
| 0.019548
|
O96028,P61978,P63241,Q9P2D1,Q9UHX1,O60826,Q6DKJ4,Q9Y619,Q9H9S5
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
191,318,347,221,8,107,117,57,283
|
2897,1576,2725,107,2630,383,191,519,2161,3205,2980,2828,318,347,1660,1158,2797,707,117,825,870,283,2088,221,8,2089,1512,655,657,1230,57
|
-0.6988183969795223,-0.09381103021537567,-0.5995724062727221,2.1809317216381077,-0.5503155785430718,0.9163495326117879,1.6052450348577447,0.6556730905320322,-0.33156716576876,-0.977013463993979,-0.7488153183487716,-0.6490720698046804,1.0657844750365362,0.9806232501634713,-0.11734646334023954,0.1157104547340278,-0.6242916466860307,0.4338422448747199,2.083474851760708,0.3438753282799643,0.2986183093020084,1.213377883648462,-0.28358176189719153,1.4623099427802935,5.057543677692156,-0.28358176189719153,-0.04689579872958434,0.5008477318133796,0.5008477318133796,0.09263033605246422,2.8994929547828066
| 3,430
|
Abnormal choroid morphology
| 13
| 30
| 2.329241
| 0.019846
|
O14936,Q9P2D1,P40939,P40855,Q01082,O60826,Q8NAT1,O43505,O15078,P04439,P53701,Q9Y619,Q9H9S5
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
530,221,386,577,483,107,273,146,304,335,276,57,283
|
530,304,146,2101,107,2726,1921,1931,335,2824,1340,1705,577,386,1817,634,276,483,921,1157,1158,768,896,3170,273,2607,1732,283,221,57
|
0.6336831437767028,1.1081387881403877,1.866485968870282,-0.30754673593761184,2.1809317216381077,-0.5995724062727221,-0.23581657417804916,-0.23581657417804916,1.0019706637911983,-0.6490720698046804,0.02309332399172761,-0.1409342612489813,0.567458949308088,0.9163495326117879,-0.18826843715602568,0.5008477318133796,1.2343164607296082,0.7213921450541884,0.25317576686812393,0.1157104547340278,0.1157104547340278,0.38894919874105743,0.2759203789757193,-0.900350577456945,1.2552190861703458,-0.5257770590663371,-0.1409342612489813,1.213377883648462,1.4623099427802935,2.8994929547828066
| 3,430
|
Abnormal retinal artery morphology
| 7
| 22
| 2.325819
| 0.020028
|
P17900,P06865,P07602,P03886,P16278,Q13510,P10619
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
89,99,36,15,179,313,25
|
3012,1750,1576,15,99,36,918,25,2682,179,89,1586,2828,2275,1660,313,707,1894,381,652,2089,657
|
-0.7739090091989397,-0.16457479426822091,-0.09381103021537567,4.652417670407559,2.277678317409277,3.495034957042614,0.25317576686812393,4.1354813465701925,-0.5749138732638202,1.6457867663301875,2.431035510324411,-0.09381103021537567,-0.6490720698046804,-0.3797760297676727,-0.11734646334023954,1.0869803140135814,0.4338422448747199,-0.2120155691768394,0.937812905361756,0.5008477318133796,-0.28358176189719153,0.5008477318133796
| 3,430
|
Oxidoreduction driven active transmembrane transporter activity
| 10
| 32
| 2.316957
| 0.020506
|
O43676,P13073,Q9Y6M9,P51970,P00403,P03886,P14854,Q9P0J0,O75306,Q9UDW1
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
35,409,373,425,394,15,424,211,309,284
|
698,2257,35,2775,2104,309,1697,1187,1920,753,2780,1579,610,394,15,1290,1522,409,424,2578,1025,2736,2688,439,3196,425,1950,1537,968,211,284,373
|
0.4338422448747199,-0.3797760297676727,3.512707326927762,-0.6242916466860307,-0.30754673593761184,1.0869803140135814,-0.1409342612489813,0.09263033605246422,-0.23581657417804916,0.38894919874105743,-0.6242916466860307,-0.09381103021537567,0.5230949161824157,0.8948470616767685,4.652417670407559,0.04632210615831087,-0.07032759590587762,0.8517239183017473,0.8301027868261046,-0.5257770590663371,0.18465877239643577,-0.5995724062727221,-0.5749138732638202,0.8084416390325024,-0.9513913766449668,0.8301027868261046,-0.23581657417804916,-0.07032759590587762,0.23038416792428346,1.5033154527373318,1.213377883648462,0.9592374039290533
| 3,430
|
Cis golgi network
| 6
| 16
| 2.316852
| 0.020512
|
O00461,Q08379,Q8TBA6,Q9NPR9,P24390,O43731
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
33,387,198,41,13,123
|
33,123,855,13,920,762,387,398,1304,198,1674,1210,2754,1045,41,2365
|
3.7405615380913355,2.0246528531620718,0.2986183093020084,4.7179169525566556,0.25317576686812393,0.38894919874105743,0.9163495326117879,0.8948470616767685,0.04632210615831087,1.5849251978248329,-0.11734646334023954,0.09263033605246422,-0.5995724062727221,0.18465877239643577,3.35288880751217,-0.4039652952055236
| 3,430
|
Submucous cleft of soft and hard palate
| 7
| 24
| 2.309609
| 0.02091
|
Q15392,O43175,Q7LGA3,O75844,Q8NAT1,O43505,Q9Y619
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
34,232,171,139,273,146,57
|
2201,232,146,139,954,2161,1342,994,1939,1485,2280,1869,1595,2285,34,171,825,273,581,1323,283,655,3355,57
|
-0.35564345936189407,1.400546940102355,1.866485968870282,1.9260244005596443,0.23038416792428346,-0.33156716576876,0.02309332399172761,0.20754527371745304,-0.23581657417804916,-0.04689579872958434,-0.3797760297676727,-0.2120155691768394,-0.09381103021537567,-0.3797760297676727,3.583187167896173,1.7063569746264826,0.3438753282799643,1.2552190861703458,0.567458949308088,0.04632210615831087,1.213377883648462,0.5008477318133796,-1.369914466388914,2.8994929547828066
| 3,430
|
Respirasome
| 16
| 45
| 2.298127
| 0.021555
|
O43676,P13073,Q96CU9,Q9Y6M9,O14949,P51970,P00403,P03886,P14854,Q9P0J0,O75306,P22695,P14406,P47985,Q9UDW1,Q6DKK2
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
35,409,103,373,243,425,394,15,424,211,309,274,56,439,284,31
|
698,2257,243,35,2775,2104,309,1697,1187,1920,753,2780,1579,610,394,15,1290,1477,1522,409,56,424,3204,3086,2578,1025,1763,274,2736,2583,2688,439,3196,425,764,1950,1537,31,968,474,103,211,284,2197,373
|
0.4338422448747199,-0.3797760297676727,1.338473936006947,3.512707326927762,-0.6242916466860307,-0.30754673593761184,1.0869803140135814,-0.1409342612489813,0.09263033605246422,-0.23581657417804916,0.38894919874105743,-0.6242916466860307,-0.09381103021537567,0.5230949161824157,0.8948470616767685,4.652417670407559,0.04632210615831087,-0.04689579872958434,-0.07032759590587762,0.8517239183017473,2.9362983424259714,0.8301027868261046,-0.977013463993979,-0.8242894260138783,-0.5257770590663371,0.18465877239643577,-0.16457479426822091,1.2343164607296082,-0.5995724062727221,-0.5257770590663371,-0.5749138732638202,0.8084416390325024,-0.9513913766449668,0.8301027868261046,0.38894919874105743,-0.23581657417804916,-0.07032759590587762,3.7926560390546924,0.23038416792428346,0.7432157338415764,2.239063866307495,1.5033154527373318,1.213377883648462,-0.33156716576876,0.9592374039290533
| 3,430
|
Glycosphingolipid metabolic process
| 6
| 10
| 2.295577
| 0.0217
|
P06865,P04062,O60512,P16278,P17900,P06280
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
99,213,150,179,89,156
|
150,213,156,99,918,179,89,1824,617,381
|
1.8465787199040886,1.4828295622266432,1.8066716660719826,2.277678317409277,0.25317576686812393,1.6457867663301875,2.431035510324411,-0.18826843715602568,0.5230949161824157,0.937812905361756
| 3,430
|
Cherry red spot of the macula
| 6
| 10
| 2.274796
| 0.022918
|
P06865,P07602,Q13510,P16278,P17900,P10619
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
99,36,313,179,89,25
|
99,36,918,25,2682,179,89,313,381,652
|
2.277678317409277,3.495034957042614,0.25317576686812393,4.1354813465701925,-0.5749138732638202,1.6457867663301875,2.431035510324411,1.0869803140135814,0.937812905361756,0.5008477318133796
| 3,430
|
Decreased activity of mitochondrial complex i
| 10
| 36
| 2.229827
| 0.025759
|
Q9Y584,O43676,Q70HW3,Q96CU9,Q9Y6M9,P51970,P03886,O75306,Q86Y39,Q9UBX3
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
96,35,102,103,373,425,15,309,474,189
|
698,35,2104,309,1697,1920,1062,610,15,2578,2736,1937,3196,425,1592,2116,471,2454,102,474,898,2182,2608,103,1501,1455,2891,2760,1509,1142,875,721,189,2199,96,373
|
0.4338422448747199,3.512707326927762,-0.30754673593761184,1.0869803140135814,-0.1409342612489813,-0.23581657417804916,0.16172434863187643,0.5230949161824157,4.652417670407559,-0.5257770590663371,-0.5995724062727221,-0.23581657417804916,-0.9513913766449668,0.8301027868261046,-0.09381103021537567,-0.30754673593761184,0.7432157338415764,-0.4525156104496164,2.239063866307495,0.7432157338415764,0.2759203789757193,-0.33156716576876,-0.5257770590663371,2.239063866307495,-0.04689579872958434,-0.02351528122041195,-0.6739141572295496,-0.5995724062727221,-0.04689579872958434,0.1387416835614649,0.2986183093020084,0.4338422448747199,1.6255321690560474,-0.33156716576876,2.3353920752424693,0.9592374039290533
| 3,430
|
Azurophil granule lumen
| 13
| 44
| 2.202417
| 0.027636
|
Q9BTY2,P61916,O00754,O00584,O00560,Q9H7Z7,P08236,P16278,P17900,P10619,P06280,P15586,Q9Y5Z4
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
128,256,66,249,300,143,246,179,89,25,156,218,322
|
300,249,66,811,2901,1422,156,2105,2106,918,246,25,2159,730,218,179,89,1650,2870,1940,3162,2382,2328,2166,2694,256,2589,1434,2915,2448,1824,618,1776,2134,580,1500,2022,1793,357,128,143,3258,2362,322
|
1.1292601049826305,1.3177131892594451,2.8070566341243905,0.3438753282799643,-0.6988183969795223,-0.02351528122041195,1.8066716660719826,-0.30754673593761184,-0.30754673593761184,0.25317576686812393,1.338473936006947,4.1354813465701925,-0.33156716576876,0.4114181815276483,1.4623099427802935,1.6457867663301875,2.431035510324411,-0.11734646334023954,-0.6739141572295496,-0.23581657417804916,-0.900350577456945,-0.42821167915506675,-0.4039652952055236,-0.33156716576876,-0.5749138732638202,1.296917258531428,-0.5257770590663371,-0.02351528122041195,-0.6988183969795223,-0.4525156104496164,-0.18826843715602568,0.5230949161824157,-0.16457479426822091,-0.30754673593761184,0.567458949308088,-0.04689579872958434,-0.25967184066824295,-0.16457479426822091,0.9806232501634713,2.0049867171526095,1.906208661011561,-1.0542934068429035,-0.4039652952055236,1.0657844750365362
| 3,430
|
Endoplasmic reticulum golgi intermediate compartment membrane
| 10
| 26
| 2.201197
| 0.027722
|
Q12907,Q8N511,Q08379,P49257,Q03518,P24390,Q13190,O15260,Q10472,Q9Y282
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
413,67,387,263,74,13,496,149,469,61
|
149,950,985,1577,13,2904,263,762,2380,2329,74,1073,387,469,413,496,2601,522,67,1895,775,3301,2190,61,2365,2036
|
1.8465787199040886,0.23038416792428346,0.20754527371745304,-0.09381103021537567,4.7179169525566556,-0.6988183969795223,1.2760859545124026,0.38894919874105743,-0.42821167915506675,-0.4039652952055236,2.620328163937606,0.16172434863187643,0.9163495326117879,0.7432157338415764,0.8517239183017473,0.6995273401513898,-0.5257770590663371,0.6556730905320322,2.8070566341243905,-0.2120155691768394,0.38894919874105743,-1.15832093411627,-0.33156716576876,2.8625913164326255,-0.4039652952055236,-0.25967184066824295
| 3,430
|
Membrane lipid biosynthetic process
| 6
| 22
| 2.198399
| 0.027921
|
Q96G23,P27544,O95470,O60512,P04062,Q06136
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
68,82,147,150,213,59
|
548,1633,502,150,1805,147,213,1649,82,1824,59,313,1305,3124,1007,1962,68,2965,1620,1278,1688,1973
|
0.6116509767559337,-0.11734646334023954,0.6776210718932071,1.8465787199040886,-0.18826843715602568,1.866485968870282,1.4828295622266432,-0.11734646334023954,2.54492504446314,-0.18826843715602568,2.8625913164326255,1.0869803140135814,0.04632210615831087,-0.849577203134417,0.20754527371745304,-0.23581657417804916,2.7884960733515816,-0.7237852836123975,-0.09381103021537567,0.06950099771551356,-0.11734646334023954,-0.23581657417804916
| 3,430
|
Establishment of protein localization to mitochondrial membrane
| 9
| 19
| 2.197041
| 0.028018
|
Q9Y584,Q15070,Q9Y5J9,P0DP25,O14737,O94826,Q9P0J0,Q9Y5L4,Q9NS69
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
96,350,225,324,70,233,211,183,23
|
809,70,233,661,324,2687,2944,617,350,1305,1083,23,211,2197,546,96,421,225,183
|
0.3438753282799643,2.6953211040640213,1.400546940102355,0.4785567416325205,1.0445510616836513,-0.5749138732638202,-0.7237852836123975,0.5230949161824157,0.9806232501634713,0.04632210615831087,0.16172434863187643,4.236863344428605,1.5033154527373318,-0.33156716576876,0.6336831437767028,2.3353920752424693,0.8517239183017473,1.4417564181063023,1.6457867663301875
| 3,430
|
Negative regulation of mrna catabolic process
| 12
| 24
| 2.195504
| 0.028127
|
Q9Y2W1,O60506,P98175,Q99729,Q14011,P35637,P11940,P07910,Q14103,Q06787,Q92804,P67809
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
584,292,397,430,426,140,518,517,443,153,187,252
|
744,292,1518,517,518,140,252,397,2063,153,1825,2917,2391,637,426,443,1440,1668,1961,187,430,1220,1687,584
|
0.38894919874105743,1.171392087430195,-0.07032759590587762,0.6556730905320322,0.6556730905320322,1.9260244005596443,1.3177131892594451,0.8948470616767685,-0.28358176189719153,1.826640669391119,-0.18826843715602568,-0.6988183969795223,-0.42821167915506675,0.5008477318133796,0.8301027868261046,0.8084416390325024,-0.02351528122041195,-0.11734646334023954,-0.23581657417804916,1.6255321690560474,0.8301027868261046,0.09263033605246422,-0.11734646334023954,0.567458949308088
| 3,430
|
SLC superfamily of solute carriers
| 14
| 41
| 2.192781
| 0.028323
|
Q9BQT8,O95202,Q70HW3,Q9BSK2,Q9H2V7,O43772,P55011,Q15043,Q9H2D1,Q6NUK1,Q9Y619,Q8TB61,Q9UBX3,Q8IXU6
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
486,383,102,136,104,109,495,365,151,472,57,92,189,127
|
1469,109,1855,699,383,1520,2049,1988,1338,631,885,504,2381,1657,495,1350,1247,365,1121,3392,472,3103,102,127,92,827,3227,486,136,903,1010,151,104,1903,1326,652,189,977,57,834,835
|
-0.04689579872958434,2.1420351304999743,-0.2120155691768394,0.4338422448747199,0.9163495326117879,-0.07032759590587762,-0.28358176189719153,-0.25967184066824295,0.02309332399172761,0.5008477318133796,0.2759203789757193,0.6776210718932071,-0.42821167915506675,-0.11734646334023954,0.6995273401513898,0.02309332399172761,0.06950099771551356,0.9592374039290533,0.1387416835614649,-1.9788713010588765,0.7432157338415764,-0.8242894260138783,2.239063866307495,2.0049867171526095,2.4119608690616183,0.3438753282799643,-1.0027041076562464,0.7213921450541884,1.965565398534416,0.2759203789757193,0.20754527371745304,1.8465787199040886,2.2197146760906703,-0.2120155691768394,0.04632210615831087,0.5008477318133796,1.6255321690560474,0.23038416792428346,2.8994929547828066,0.3438753282799643,0.3438753282799643
| 3,430
|
Regulation of alternative mrna splicing via spliceosome
| 9
| 33
| 2.18557
| 0.028847
|
P51116,P98175,Q9UHX1,P38159,P31483,P51114,Q07666,Q06787,P52756
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
197,397,8,262,364,87,403,153,507
|
3260,2321,1933,2268,1646,2640,364,262,1528,87,197,507,1071,397,2063,153,403,2497,1876,1878,2070,795,2181,1169,1498,1503,1406,719,1138,8,584,1182,1230
|
-1.0801932550383022,-0.4039652952055236,-0.23581657417804916,-0.3797760297676727,-0.11734646334023954,-0.5503155785430718,0.9592374039290533,1.2760859545124026,-0.07032759590587762,2.4691045637919236,1.5849251978248329,0.6776210718932071,0.16172434863187643,0.8948470616767685,-0.28358176189719153,1.826640669391119,0.8733052663722602,-0.4768775233718424,-0.2120155691768394,-0.2120155691768394,-0.28358176189719153,0.36643501064183787,-0.33156716576876,0.1157104547340278,-0.04689579872958434,-0.04689579872958434,-0.00018569005958125493,0.4338422448747199,0.1387416835614649,5.057543677692156,0.567458949308088,0.1157104547340278,0.09263033605246422
| 3,430
|
Protein transmembrane transport
| 7
| 25
| 2.185085
| 0.028883
|
Q15629,Q9Y584,O60830,O43615,Q9NS69,O14925,Q99595
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
64,96,97,134,23,122,157
|
122,134,97,2726,233,1930,2678,3085,729,762,1817,3382,3116,2834,1248,820,64,1538,2459,1216,157,1412,23,653,96
|
2.0442894948035293,1.965565398534416,2.3161817108012213,-0.5995724062727221,1.400546940102355,-0.23581657417804916,-0.5749138732638202,-0.8242894260138783,0.4114181815276483,0.38894919874105743,-0.18826843715602568,-1.8085387445922683,-0.849577203134417,-0.6490720698046804,0.06950099771551356,0.3438753282799643,2.825592626630927,-0.07032759590587762,-0.4525156104496164,0.09263033605246422,1.8066716660719826,-0.00018569005958125493,4.236863344428605,0.5008477318133796,2.3353920752424693
| 3,430
|
Proton transmembrane transporter activity
| 12
| 35
| 2.18332
| 0.029012
|
P56385,P13073,O95202,Q93050,P00403,P14854,P24539,Q96ES6,O75964,Q9Y487,P47985,Q9UDW1
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
440,409,383,45,394,424,494,18,52,24,439,284
|
2262,52,383,394,2049,491,1290,1522,631,409,424,1025,3205,3321,494,3111,2688,1152,663,992,439,2831,3266,440,2167,1350,764,968,45,18,1903,284,2032,24,808
|
-0.3797760297676727,3.1007524055777593,0.9163495326117879,0.8948470616767685,-0.28358176189719153,0.6995273401513898,0.04632210615831087,-0.07032759590587762,0.5008477318133796,0.8517239183017473,0.8301027868261046,0.18465877239643577,-0.977013463993979,-1.2371040916101648,0.6995273401513898,-0.849577203134417,-0.5749138732638202,0.1157104547340278,0.4785567416325205,0.20754527371745304,0.8084416390325024,-0.6490720698046804,-1.0801932550383022,0.8084416390325024,-0.33156716576876,0.02309332399172761,0.38894919874105743,0.23038416792428346,3.2093487244594585,4.404391230829396,-0.2120155691768394,1.213377883648462,-0.25967184066824295,4.186254663337337,0.36643501064183787
| 3,430
|
Antigen binding
| 6
| 10
| 2.181095
| 0.029176
|
Q15392,Q03518,P01889,P10321,P04439,P55899
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
34,74,329,402,335,287
|
985,329,335,402,532,287,74,1073,34,1839
|
0.20754527371745304,1.0232798624432902,1.0019706637911983,0.8733052663722602,0.6336831437767028,1.1924031585962547,2.620328163937606,0.16172434863187643,3.583187167896173,-0.18826843715602568
| 3,430
|
Agitation
| 6
| 33
| 2.176346
| 0.029529
|
Q15165,P35637,P05067,P42892,P48449,Q92804
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
1,140,46,49,112,187
|
1186,1638,2678,213,46,1475,1933,589,2941,857,140,412,49,858,112,614,2793,634,2166,483,1944,2391,766,1777,1,3150,1164,1205,2128,187,3127,3393,2560
|
0.09263033605246422,-0.11734646334023954,-0.5749138732638202,1.4828295622266432,3.191306028311356,-0.04689579872958434,-0.23581657417804916,0.5452985658990057,-0.7237852836123975,0.2986183093020084,1.9260244005596443,0.8517239183017473,3.1189087835415297,0.2986183093020084,2.122543890584666,0.5230949161824157,-0.6242916466860307,0.5008477318133796,-0.33156716576876,0.7213921450541884,-0.23581657417804916,-0.42821167915506675,0.38894919874105743,-0.16457479426822091,6.5440889483340765,-0.8749307389569164,0.1157104547340278,0.09263033605246422,-0.30754673593761184,1.6255321690560474,-0.849577203134417,-1.9788713010588765,-0.5012978577516536
| 3,430
|
Sphingolipid metabolism
| 6
| 12
| 2.170928
| 0.029937
|
O95470,P04062,P16278,Q13510,Q06136,P06280
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
147,213,179,313,59,156
|
548,1633,811,147,213,156,730,179,59,313,381,1278
|
0.6116509767559337,-0.11734646334023954,0.3438753282799643,1.866485968870282,1.4828295622266432,1.8066716660719826,0.4114181815276483,1.6457867663301875,2.8625913164326255,1.0869803140135814,0.937812905361756,0.06950099771551356
| 3,430
|
Metallopeptidase activity
| 11
| 41
| 2.16464
| 0.030415
|
Q99797,Q9NZ08,O75844,Q9UIQ6,Q969V3,O75976,P42892,O95630,P22695,P55786,Q5JRX3
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
199,299,139,12,172,142,49,245,274,152,126
|
2314,2625,748,951,1578,139,142,245,728,311,2324,2267,274,3143,1068,49,3322,1654,2220,152,1157,126,793,1309,2346,543,172,2847,1320,1008,199,3171,1175,2303,3045,3187,2716,299,12,1628,948
|
-0.4039652952055236,-0.5503155785430718,0.38894919874105743,0.23038416792428346,-0.09381103021537567,1.9260244005596443,1.906208661011561,1.338473936006947,0.4114181815276483,1.0869803140135814,-0.4039652952055236,-0.3797760297676727,1.2343164607296082,-0.8749307389569164,0.16172434863187643,3.1189087835415297,-1.2371040916101648,-0.11734646334023954,-0.35564345936189407,1.826640669391119,0.1157104547340278,2.0049867171526095,0.36643501064183787,0.04632210615831087,-0.4039652952055236,0.6336831437767028,1.7063569746264826,-0.6490720698046804,0.04632210615831087,0.20754527371745304,1.5849251978248329,-0.900350577456945,0.1157104547340278,-0.3797760297676727,-0.7739090091989397,-0.9258372702304992,-0.5749138732638202,1.1503444701717498,4.766868416503872,-0.09381103021537567,0.25317576686812393
| 3,430
|
Calmodulin
| 7
| 16
| 2.163589
| 0.030496
|
Q8IYU8,P80303,P41208,Q14257,O43852,Q9BRK5,Q02818
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
296,9,116,85,184,90,125
|
184,324,2827,116,2950,2385,9,125,85,1201,2959,1546,296,2549,601,90
|
1.6255321690560474,1.0445510616836513,-0.6490720698046804,2.083474851760708,-0.7237852836123975,-0.42821167915506675,4.993390704618005,2.0246528531620718,2.4880992123030645,0.09263033605246422,-0.7237852836123975,-0.07032759590587762,1.1503444701717498,-0.5012978577516536,0.5452985658990057,2.431035510324411
| 3,430
|
Intracellular calcium-sensing protein
| 7
| 16
| 2.163589
| 0.030496
|
Q8IYU8,P80303,P41208,Q14257,O43852,Q9BRK5,Q02818
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
296,9,116,85,184,90,125
|
184,324,2827,116,2950,2385,9,125,85,1201,2959,1546,296,2549,601,90
|
1.6255321690560474,1.0445510616836513,-0.6490720698046804,2.083474851760708,-0.7237852836123975,-0.42821167915506675,4.993390704618005,2.0246528531620718,2.4880992123030645,0.09263033605246422,-0.7237852836123975,-0.07032759590587762,1.1503444701717498,-0.5012978577516536,0.5452985658990057,2.431035510324411
| 3,430
|
Rna stabilization
| 12
| 27
| 2.163045
| 0.030538
|
Q9Y2W1,O60506,P98175,Q9H2U1,Q14011,P35637,P11940,P07910,O95453,Q14103,Q92804,P67809
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
584,292,397,431,426,140,518,517,119,443,187,252
|
292,2861,1518,119,517,518,140,252,397,2063,1825,1869,2917,2391,637,426,443,1440,1668,1961,187,1041,1220,431,904,1687,584
|
1.171392087430195,-0.6739141572295496,-0.07032759590587762,2.063896781548296,0.6556730905320322,0.6556730905320322,1.9260244005596443,1.3177131892594451,0.8948470616767685,-0.28358176189719153,-0.18826843715602568,-0.2120155691768394,-0.6988183969795223,-0.42821167915506675,0.5008477318133796,0.8301027868261046,0.8084416390325024,-0.02351528122041195,-0.11734646334023954,-0.23581657417804916,1.6255321690560474,0.18465877239643577,0.09263033605246422,0.8301027868261046,0.2759203789757193,-0.11734646334023954,0.567458949308088
| 3,430
|
Vacuole organization
| 9
| 53
| 2.157663
| 0.030954
|
Q14108,Q8N511,P50897,P54802,O75503,P10253,Q8TBX8,P11117,O14773
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
130,67,6,40,138,144,176,79,121
|
809,121,1577,138,1926,1754,1699,1700,213,2105,918,144,79,886,482,1114,6,2057,40,1768,2540,2168,1158,130,665,2500,1598,1304,1078,1163,1834,642,67,176,1674,1732,1895,2888,3127,2190,1221,1047,1741,2358,1178,1627,2974,979,2034,1913,3284,2367,2038
|
0.3438753282799643,2.0442894948035293,-0.09381103021537567,1.9260244005596443,-0.23581657417804916,-0.16457479426822091,-0.1409342612489813,-0.1409342612489813,1.4828295622266432,-0.30754673593761184,0.25317576686812393,1.8863625663085712,2.5638146678084146,0.2759203789757193,0.7213921450541884,0.1387416835614649,5.121449989369716,-0.28358176189719153,3.370732425976295,-0.16457479426822091,-0.5012978577516536,-0.33156716576876,0.1157104547340278,1.9852909461843653,0.4785567416325205,-0.4768775233718424,-0.09381103021537567,0.04632210615831087,0.16172434863187643,0.1157104547340278,-0.18826843715602568,0.5008477318133796,2.8070566341243905,1.6861990067024655,-0.11734646334023954,-0.1409342612489813,-0.2120155691768394,-0.6739141572295496,-0.849577203134417,-0.33156716576876,0.09263033605246422,0.18465877239643577,-0.1409342612489813,-0.4039652952055236,0.1157104547340278,-0.09381103021537567,-0.7237852836123975,0.23038416792428346,-0.25967184066824295,-0.2120155691768394,-1.1061640452367623,-0.4039652952055236,-0.25967184066824295
| 3,430
|
calmodulin-related
| 7
| 14
| 2.156531
| 0.031042
|
Q8IYU8,P80303,P41208,Q14257,O43852,Q9BRK5,Q02818
|
Functions
|
Panther Protein class
|
panther_protein_class
|
296,9,116,85,184,90,125
|
184,324,2943,2827,116,2385,9,125,85,1201,296,3106,601,90
|
1.6255321690560474,1.0445510616836513,-0.7237852836123975,-0.6490720698046804,2.083474851760708,-0.42821167915506675,4.993390704618005,2.0246528531620718,2.4880992123030645,0.09263033605246422,1.1503444701717498,-0.8242894260138783,0.5452985658990057,2.431035510324411
| 3,430
|
Bruising susceptibility
| 13
| 32
| 2.153019
| 0.031317
|
Q14108,Q15149,Q9NWM8,P49257,P10644,P51798,Q13126,P38435,O60568,P04062,Q96L58,Q6UN15,O15360
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
130,454,137,263,589,520,205,145,550,213,215,540,433
|
2773,433,550,213,2434,589,2160,3233,2980,1650,2482,1110,145,2113,1814,263,1653,520,2280,1533,1824,2281,205,130,1875,454,540,215,648,137,1465,1180
|
-0.6242916466860307,0.8084416390325024,0.6116509767559337,1.4828295622266432,-0.4525156104496164,0.5452985658990057,-0.33156716576876,-1.0284638912585382,-0.7488153183487716,-0.11734646334023954,-0.4768775233718424,0.1387416835614649,1.8863625663085712,-0.30754673593761184,-0.18826843715602568,1.2760859545124026,-0.11734646334023954,0.6556730905320322,-0.3797760297676727,-0.07032759590587762,-0.18826843715602568,-0.3797760297676727,1.5441867444483162,1.9852909461843653,-0.2120155691768394,0.7867402397027633,0.6336831437767028,1.4828295622266432,0.5008477318133796,1.9458099313348363,-0.02351528122041195,0.1157104547340278
| 3,430
|
Ventricular hypertrophy
| 13
| 40
| 2.149258
| 0.031614
|
Q96MF7,P40939,P46976,O75844,O43772,P00403,P03886,P10253,P23786,P14854,O95630,Q9H9S5,P06280
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
290,386,331,139,109,394,15,144,270,424,245,283,156
|
2773,109,1335,139,752,245,394,954,15,156,144,2635,631,1645,424,1763,270,2583,1389,1706,663,3247,386,2948,331,2646,841,1947,2499,709,472,1605,2294,2608,290,1134,1140,1738,283,1909
|
-0.6242916466860307,2.1420351304999743,0.02309332399172761,1.9260244005596443,0.38894919874105743,1.338473936006947,0.8948470616767685,0.23038416792428346,4.652417670407559,1.8066716660719826,1.8863625663085712,-0.5503155785430718,0.5008477318133796,-0.11734646334023954,0.8301027868261046,-0.16457479426822091,1.2552190861703458,-0.5257770590663371,-0.00018569005958125493,-0.1409342612489813,0.4785567416325205,-1.0542934068429035,0.9163495326117879,-0.7237852836123975,1.0232798624432902,-0.5503155785430718,0.32126985958171844,-0.23581657417804916,-0.4768775233718424,0.4338422448747199,0.7432157338415764,-0.09381103021537567,-0.3797760297676727,-0.5257770590663371,1.1924031585962547,0.1387416835614649,0.1387416835614649,-0.1409342612489813,1.213377883648462,-0.2120155691768394
| 3,430
|
Clumsiness
| 14
| 21
| 2.143836
| 0.032046
|
P42858,O14773,P15289,O00754,P07602,Q9NZJ7,O75503,P31483,Q05086,O43819,Q13510,O43681,Q9NR77,Q15067
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
412,121,730,66,36,652,138,364,595,360,313,811,60,666
|
66,121,1853,811,360,138,813,36,730,2583,364,412,595,313,666,2805,967,1134,60,652,1225
|
2.8070566341243905,2.0442894948035293,-0.2120155691768394,0.3438753282799643,0.9592374039290533,1.9260244005596443,0.3438753282799643,3.495034957042614,0.4114181815276483,-0.5257770590663371,0.9592374039290533,0.8517239183017473,0.5452985658990057,1.0869803140135814,0.4785567416325205,-0.6242916466860307,0.23038416792428346,0.1387416835614649,2.8625913164326255,0.5008477318133796,0.09263033605246422
| 3,430
|
Cytochrome complex assembly
| 7
| 12
| 2.142642
| 0.032142
|
Q15070,Q9BSK2,Q9Y2R0,O43819,P53701,Q69YU5,Q6DKK2
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
350,136,81,360,276,30,31
|
360,752,439,276,350,30,31,968,136,3190,2197,81
|
0.9592374039290533,0.38894919874105743,0.8084416390325024,1.2343164607296082,0.9806232501634713,3.861838008707718,3.7926560390546924,0.23038416792428346,1.965565398534416,-0.9258372702304992,-0.33156716576876,2.5638146678084146
| 3,430
|
Monovalent inorganic cation homeostasis
| 10
| 28
| 2.124541
| 0.033625
|
Q8N511,Q15904,P50897,O75503,Q93050,P55011,P06576,Q9Y5X3,Q9Y487,Q92544
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
67,522,6,138,45,495,491,574,24,511
|
138,1754,1642,1423,491,2158,2581,1650,6,2057,2384,495,2167,595,522,67,511,45,1732,2888,1215,903,2421,2032,24,574,3403,835
|
1.9260244005596443,-0.16457479426822091,-0.11734646334023954,-0.02351528122041195,0.6995273401513898,-0.33156716576876,-0.5257770590663371,-0.11734646334023954,5.121449989369716,-0.28358176189719153,-0.42821167915506675,0.6995273401513898,-0.33156716576876,0.5452985658990057,0.6556730905320322,2.8070566341243905,0.6776210718932071,3.2093487244594585,-0.1409342612489813,-0.6739141572295496,0.09263033605246422,0.2759203789757193,-0.42821167915506675,-0.25967184066824295,4.186254663337337,0.5895763319810627,-2.211483395059946,0.3438753282799643
| 3,430
|
Electron transport
| 17
| 46
| 2.122642
| 0.033784
|
Q16134,Q86Y39,O43676,Q96CU9,Q9Y6M9,O14949,P51970,P00403,P03886,Q9P0J0,Q9H1E5,O75306,O43169,P22695,P47985,Q9UDW1,Q6DKK2
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
224,474,35,103,373,243,425,394,15,211,279,309,55,274,439,284,31
|
698,2257,243,55,467,35,2775,2104,309,1697,1187,1920,753,2780,1579,2373,610,394,15,1290,3175,3204,2578,1763,2213,274,2736,2583,2688,3248,439,3196,425,224,1950,1537,2603,31,474,103,2557,279,1736,211,284,373
|
0.4338422448747199,-0.3797760297676727,1.338473936006947,2.9546651894343055,0.7432157338415764,3.512707326927762,-0.6242916466860307,-0.30754673593761184,1.0869803140135814,-0.1409342612489813,0.09263033605246422,-0.23581657417804916,0.38894919874105743,-0.6242916466860307,-0.09381103021537567,-0.42821167915506675,0.5230949161824157,0.8948470616767685,4.652417670407559,0.04632210615831087,-0.9258372702304992,-0.977013463993979,-0.5257770590663371,-0.16457479426822091,-0.35564345936189407,1.2343164607296082,-0.5995724062727221,-0.5257770590663371,-0.5749138732638202,-1.0542934068429035,0.8084416390325024,-0.9513913766449668,0.8301027868261046,1.4417564181063023,-0.23581657417804916,-0.07032759590587762,-0.5257770590663371,3.7926560390546924,0.7432157338415764,2.239063866307495,-0.5012978577516536,1.2343164607296082,-0.1409342612489813,1.5033154527373318,1.213377883648462,0.9592374039290533
| 3,430
|
Sterol metabolism
| 10
| 26
| 2.103386
| 0.035432
|
Q16850,Q15392,P61916,O15118,O76062,Q15800,Q14739,P54646,P04062,Q9UBM7
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
351,34,256,164,69,178,50,336,213,154
|
164,587,1421,69,1519,2901,213,1990,2213,857,385,3412,336,256,1868,2591,3347,50,3099,34,1880,178,351,154,1800,1376
|
1.7465774077703615,0.5452985658990057,-0.02351528122041195,2.714006070492743,-0.07032759590587762,-0.6988183969795223,1.4828295622266432,-0.25967184066824295,-0.35564345936189407,0.2986183093020084,0.9163495326117879,-2.360290770874015,1.0019706637911983,1.296917258531428,-0.2120155691768394,-0.5257770590663371,-1.3431986759033332,3.1189087835415297,-0.8242894260138783,3.583187167896173,-0.2120155691768394,1.6660089911781828,0.9806232501634713,1.826640669391119,-0.16457479426822091,0.02309332399172761
| 3,430
|
Retrograde vesicle mediated transport golgi to endoplasmic reticulum
| 7
| 27
| 2.101042
| 0.035637
|
P42858,P24390,Q9P2W9,O43731,Q8TD16,Q9Y282,Q6NUQ1
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
412,13,177,123,314,61,258
|
744,1057,1854,985,123,1577,531,13,760,412,1864,1938,762,2058,2951,1943,2118,413,258,314,1674,1210,2754,776,177,2419,61
|
0.38894919874105743,0.16172434863187643,-0.2120155691768394,0.20754527371745304,2.0246528531620718,-0.09381103021537567,0.6336831437767028,4.7179169525566556,0.38894919874105743,0.8517239183017473,-0.2120155691768394,-0.23581657417804916,0.38894919874105743,-0.28358176189719153,-0.7237852836123975,-0.23581657417804916,-0.30754673593761184,0.8517239183017473,1.296917258531428,1.0869803140135814,-0.11734646334023954,0.09263033605246422,-0.5995724062727221,0.38894919874105743,1.6861990067024655,-0.42821167915506675,2.8625913164326255
| 3,430
|
Heterogeneous
| 13
| 47
| 2.099379
| 0.035784
|
P61916,Q15555,P40939,Q16836,P11717,O75844,P01889,P05067,P03886,Q8TB36,Q9BQE5,Q9Y619,Q9NR77
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
256,265,386,42,330,139,329,46,15,368,19,57,60
|
1918,2572,787,139,2728,423,329,954,15,2680,1383,46,813,1106,330,631,1856,1586,1705,1424,1813,386,1428,1027,2793,520,2874,256,2595,1250,2545,894,766,265,1880,42,2883,368,2607,3420,1735,19,1844,60,1414,2037,57
|
-0.23581657417804916,-0.5257770590663371,0.36643501064183787,1.9260244005596443,-0.5995724062727221,0.8301027868261046,1.0232798624432902,0.23038416792428346,4.652417670407559,-0.5749138732638202,-0.00018569005958125493,3.191306028311356,0.3438753282799643,0.1387416835614649,1.0232798624432902,0.5008477318133796,-0.2120155691768394,-0.09381103021537567,-0.1409342612489813,-0.02351528122041195,-0.18826843715602568,0.9163495326117879,-0.02351528122041195,0.18465877239643577,-0.6242916466860307,0.6556730905320322,-0.6739141572295496,1.296917258531428,-0.5257770590663371,0.06950099771551356,-0.5012978577516536,0.2759203789757193,0.38894919874105743,1.2760859545124026,-0.2120155691768394,3.3350234117032413,-0.6739141572295496,0.9592374039290533,-0.5257770590663371,-2.9207032885706705,-0.1409342612489813,4.3877182006716735,-0.18826843715602568,2.8625913164326255,-0.00018569005958125493,-0.25967184066824295,2.8994929547828066
| 3,430
|
Abnormality of pulmonary circulation
| 12
| 31
| 2.099026
| 0.035815
|
Q14108,Q9NZ08,O75844,P51970,P00403,P03886,Q8IZA0,P14854,P01889,P04062,Q6NUK1,O14678
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
130,299,139,425,394,15,272,424,329,213,472,466
|
466,3334,139,2781,610,394,329,954,15,213,2635,424,1025,2980,2824,3111,1652,1428,1653,520,425,130,2748,2993,1722,472,272,1732,1740,299,2368
|
0.7432157338415764,-1.31656044562432,1.9260244005596443,-0.6242916466860307,0.5230949161824157,0.8948470616767685,1.0232798624432902,0.23038416792428346,4.652417670407559,1.4828295622266432,-0.5503155785430718,0.8301027868261046,0.18465877239643577,-0.7488153183487716,-0.6490720698046804,-0.849577203134417,-0.11734646334023954,-0.02351528122041195,-0.11734646334023954,0.6556730905320322,0.8301027868261046,1.9852909461843653,-0.5995724062727221,-0.7488153183487716,-0.1409342612489813,0.7432157338415764,1.2552190861703458,-0.1409342612489813,-0.1409342612489813,1.1503444701717498,-0.4039652952055236
| 3,430
|
Bulbar signs
| 7
| 13
| 2.092422
| 0.036401
|
P07602,Q9Y263,P35637,Q99720,P03886,P04062,Q15043
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
36,527,140,47,15,213,365
|
811,15,213,813,36,730,140,858,365,523,47,652,527
|
0.3438753282799643,4.652417670407559,1.4828295622266432,0.3438753282799643,3.495034957042614,0.4114181815276483,1.9260244005596443,0.2986183093020084,0.9592374039290533,0.6556730905320322,3.173240775887535,0.5008477318133796,0.6556730905320322
| 3,430
|
Dementia
| 18
| 58
| 2.085815
| 0.036995
|
P17900,Q14108,P61916,P07602,Q9Y287,O15118,P06865,P35637,P00403,P03886,P05067,P31483,P27544,P04062,Q9Y487,Q13510,Q06787,O60313
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
89,130,256,36,166,164,99,140,394,15,46,364,82,213,24,313,153,94
|
915,164,811,94,1186,812,2678,394,15,213,2322,1641,46,99,36,1933,2732,730,89,564,1763,576,2111,82,2583,364,140,663,992,412,858,2793,840,2166,256,1662,1944,153,2391,313,130,766,1399,1205,2128,3170,2460,1082,1790,3127,499,1134,3393,652,722,166,24,2368
|
0.25317576686812393,1.7465774077703615,0.3438753282799643,2.35457505060863,0.09263033605246422,0.3438753282799643,-0.5749138732638202,0.8948470616767685,4.652417670407559,1.4828295622266432,-0.4039652952055236,-0.11734646334023954,3.191306028311356,2.277678317409277,3.495034957042614,-0.23581657417804916,-0.5995724062727221,0.4114181815276483,2.431035510324411,0.5895763319810627,-0.16457479426822091,0.567458949308088,-0.30754673593761184,2.54492504446314,-0.5257770590663371,0.9592374039290533,1.9260244005596443,0.4785567416325205,0.20754527371745304,0.8517239183017473,0.2986183093020084,-0.6242916466860307,0.32126985958171844,-0.33156716576876,1.296917258531428,-0.11734646334023954,-0.23581657417804916,1.826640669391119,-0.42821167915506675,1.0869803140135814,1.9852909461843653,0.38894919874105743,-0.00018569005958125493,0.09263033605246422,-0.30754673593761184,-0.900350577456945,-0.4525156104496164,0.16172434863187643,-0.16457479426822091,-0.849577203134417,0.6995273401513898,0.1387416835614649,-1.9788713010588765,0.5008477318133796,0.4338422448747199,1.7465774077703615,4.186254663337337,-0.4039652952055236
| 3,430
|
Mitochondrial substrate/solute carrier [IPR018108]
| 10
| 20
| 2.078414
| 0.037671
|
Q9BQT8,Q70HW3,Q9BSK2,P12235,O43772,Q9H2D1,Q6NUK1,Q9Y619,Q9NZJ7,Q9UBX3
|
Sequence
|
InterPro Repeat
|
interpro_repeat
|
486,102,136,631,109,151,472,57,652,189
|
109,1855,699,2049,631,885,2381,1350,1247,472,102,486,136,151,1903,652,189,977,57,834
|
2.1420351304999743,-0.2120155691768394,0.4338422448747199,-0.28358176189719153,0.5008477318133796,0.2759203789757193,-0.42821167915506675,0.02309332399172761,0.06950099771551356,0.7432157338415764,2.239063866307495,0.7213921450541884,1.965565398534416,1.8465787199040886,-0.2120155691768394,0.5008477318133796,1.6255321690560474,0.23038416792428346,2.8994929547828066,0.3438753282799643
| 3,430
|
Mitochondrial carrier domain superfamily [IPR023395]
| 10
| 20
| 2.078414
| 0.037671
|
Q9BQT8,Q70HW3,Q9BSK2,P12235,O43772,Q9H2D1,Q6NUK1,Q9Y619,Q9NZJ7,Q9UBX3
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
486,102,136,631,109,151,472,57,652,189
|
109,1855,699,2049,631,885,2381,1350,1247,472,102,486,136,151,1903,652,189,977,57,834
|
2.1420351304999743,-0.2120155691768394,0.4338422448747199,-0.28358176189719153,0.5008477318133796,0.2759203789757193,-0.42821167915506675,0.02309332399172761,0.06950099771551356,0.7432157338415764,2.239063866307495,0.7213921450541884,1.965565398534416,1.8465787199040886,-0.2120155691768394,0.5008477318133796,1.6255321690560474,0.23038416792428346,2.8994929547828066,0.3438753282799643
| 3,430
|
SLC25 family of mitochondrial transporters
| 10
| 20
| 2.078414
| 0.037671
|
Q9BQT8,Q70HW3,Q9BSK2,P12235,O43772,Q9H2D1,Q6NUK1,Q9Y619,Q9NZJ7,Q9UBX3
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
486,102,136,631,109,151,472,57,652,189
|
109,1855,699,2049,631,885,2381,1350,1247,472,102,486,136,151,1903,652,189,977,57,834
|
2.1420351304999743,-0.2120155691768394,0.4338422448747199,-0.28358176189719153,0.5008477318133796,0.2759203789757193,-0.42821167915506675,0.02309332399172761,0.06950099771551356,0.7432157338415764,2.239063866307495,0.7213921450541884,1.965565398534416,1.8465787199040886,-0.2120155691768394,0.5008477318133796,1.6255321690560474,0.23038416792428346,2.8994929547828066,0.3438753282799643
| 3,430
|
Confusion
| 6
| 19
| 2.076282
| 0.037868
|
O00754,Q16836,Q9NZ08,P01889,P05067,Q9Y619
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
66,42,299,329,46,57
|
66,1853,2678,329,46,2820,1338,758,1760,2111,2787,1068,386,1653,42,299,977,2368,57
|
2.8070566341243905,-0.2120155691768394,-0.5749138732638202,1.0232798624432902,3.191306028311356,-0.6490720698046804,0.02309332399172761,0.38894919874105743,-0.16457479426822091,-0.30754673593761184,-0.6242916466860307,0.16172434863187643,0.9163495326117879,-0.11734646334023954,3.3350234117032413,1.1503444701717498,0.23038416792428346,-0.4039652952055236,2.8994929547828066
| 3,430
|
Udp glycosyltransferase activity
| 8
| 17
| 2.072713
| 0.038199
|
P06865,P46976,Q8NAT1,O43505,O60512,Q96L58,Q8N4A0,Q10472
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
99,331,273,146,150,215,281,469
|
1982,146,952,150,550,99,918,1645,331,732,469,1126,281,273,1263,215,782
|
-0.25967184066824295,1.866485968870282,0.23038416792428346,1.8465787199040886,0.6116509767559337,2.277678317409277,0.25317576686812393,-0.11734646334023954,1.0232798624432902,0.4114181815276483,0.7432157338415764,0.1387416835614649,1.213377883648462,1.2552190861703458,0.06950099771551356,1.4828295622266432,0.38894919874105743
| 3,430
|
Gingival overgrowth
| 10
| 30
| 2.07068
| 0.038389
|
O00754,Q99519,P10644,Q14739,P08236,P16278,Q6DKJ4,Q6UN15,Q9UBM7,P20700
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
66,381,589,50,246,179,117,540,154,564
|
66,1576,952,1421,1699,2434,246,589,179,564,3205,2828,2113,1709,1660,1870,2333,50,1875,707,117,540,1959,1554,2965,381,154,2089,1512,657
|
2.8070566341243905,-0.09381103021537567,0.23038416792428346,-0.02351528122041195,-0.1409342612489813,-0.4525156104496164,1.338473936006947,0.5452985658990057,1.6457867663301875,0.5895763319810627,-0.977013463993979,-0.6490720698046804,-0.30754673593761184,-0.1409342612489813,-0.11734646334023954,-0.2120155691768394,-0.4039652952055236,3.1189087835415297,-0.2120155691768394,0.4338422448747199,2.083474851760708,0.6336831437767028,-0.23581657417804916,-0.07032759590587762,-0.7237852836123975,0.937812905361756,1.826640669391119,-0.28358176189719153,-0.04689579872958434,0.5008477318133796
| 3,430
|
Subsets and Splits
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