term
stringlengths
2
121
overlap
int64
6
281
setsize
int64
7
499
score
float64
1.96
10.6
pval
float64
0
0.05
edge
stringlengths
41
1.97k
type
stringclasses
5 values
subtype
stringclasses
24 values
subtype_key
stringclasses
24 values
edge_idxs
stringlengths
11
1.17k
ann_idxs
stringlengths
19
2.31k
ann_vals
stringlengths
124
9.94k
sig_size
int64
2.2k
3.73k
Atp synthesis coupled proton transport
7
11
2.517252
0.011827
O75964,P06576,P24539,Q9UJZ1,P36542,P25705,P56385
Processes and pathways
GO Biological process
msigdb_gobp
2,40,109,390,281,501,412
793,2,40,109,501,281,1791,521,3294,412,390
0.5620305844376072,5.167196520160504,2.8041124444238252,2.0394981091593998,0.8914804711800896,1.269449542990556,-0.10633468895957496,0.8693977289284917,-1.548678875208257,1.0243308327237213,1.0687484169607406
3,430
Recruitment of numa to mitotic centrosomes
13
43
2.515542
0.011885
P62258,Q14980,Q9BV73,O15078,O94927,O95613,Q14203,P41208,P61981,Q99996,O75935,Q13561,P07900
Processes and pathways
Reactome Pathways
msigdb_reactome
67,456,309,173,175,515,188,19,427,387,443,415,314
173,821,443,175,515,3005,1132,543,988,314,1632,1879,968,19,1079,2485,1141,427,67,2991,2139,1406,415,1581,1526,188,833,456,1484,696,1216,1822,886,1585,2123,387,1499,1220,309,2083,1863,3246,1285
1.6748229295823038,0.5402049440683143,0.9799801607699364,1.6748229295823038,0.8693977289284917,-0.9629504767360699,0.3012772815040069,0.8252830651235218,0.4096172898409424,1.2024003828056788,-0.02106529204966477,-0.17009375816547115,0.43133814681776855,3.204350628748325,0.34456029993080256,-0.5282207546911941,0.3012772815040069,1.0021471184507622,2.431327036159296,-0.942446145812876,-0.31821572844136564,0.12885737883854684,1.0243308327237213,0.02167903874393584,0.06449608277835585,1.6068977874861423,0.5402049440683143,0.9578299883515244,0.0859317852989234,0.6495063733352072,0.2580652147528089,-0.12760615078476442,0.4966058497171867,0.02167903874393584,-0.2971114238181862,1.0687484169607406,0.0859317852989234,0.2580652147528089,1.2247336356763627,-0.2759883981888322,-0.14885918591010985,-1.3687716700453372,0.21492436389411237
3,430
ATP synthase
9
20
2.512929
0.011973
O75964,Q9Y5K8,Q93050,P06576,P24539,P25705,P36542,Q6IN85,P56385
Functions
Panther Protein class
panther_protein_class
2,288,461,40,109,501,281,417,412
793,2,40,3023,3076,109,501,281,1791,521,3294,412,1637,2730,417,461,1763,1622,727,288
0.5620305844376072,5.167196520160504,2.8041124444238252,-0.9834347839005033,-1.0447671183808418,2.0394981091593998,0.8914804711800896,1.269449542990556,-0.10633468895957496,0.8693977289284917,-1.548678875208257,1.0243308327237213,-0.02106529204966477,-0.6948481366740377,1.0243308327237213,0.9578299883515244,-0.08504483643208101,0.0002977667180233936,0.6276115039211269,1.269449542990556
3,430
Positive regulation of translation
16
60
2.491599
0.012717
O15514,P60228,P42345,Q92552,P67809,P08670,Q7L0Y3,O60506,Q9Y2R0,Q9NWS8,P98179,Q07021,Q567V2,Q14103,P78344,P63241
Processes and pathways
GO Biological process
msigdb_gobp
163,262,233,609,235,11,628,479,49,18,536,217,431,566,283,413
1161,1949,1950,163,479,1163,2557,11,618,1516,1631,2167,233,2656,2675,2066,1674,3201,262,1525,744,3222,1963,413,235,283,1374,536,2110,1299,1209,217,2658,1641,1114,1997,2310,566,2781,431,2864,1348,2313,628,1416,1823,1647,609,2786,2321,1698,1357,1730,2460,2222,18,1944,1008,49,1327
0.2796623627116229,-0.21250736851480986,-0.21250736851480986,1.742891610000047,0.9135801145844248,0.2796623627116229,-0.569993271061387,3.824533083456319,0.7372578479891295,0.06449608277835585,-0.02106529204966477,-0.3393012744587857,1.4264710812485106,-0.6325077598761806,-0.6533072855099272,-0.2759883981888322,-0.04241010240522003,-1.2680873203022425,1.3366464985559088,0.06449608277835585,0.6057338953933035,-1.3084235436014806,-0.21250736851480986,1.0243308327237213,1.4264710812485106,1.269449542990556,0.15034720133396523,0.8473319171085857,-0.2971114238181862,0.19338072765197223,0.2580652147528089,1.4940100655111697,-0.6325077598761806,-0.02106529204966477,0.3229099381780773,-0.23368633339360326,-0.4234551139739826,0.8032512025014997,-0.736311113618571,1.0021471184507622,-0.8190021137923701,0.17185499556109507,-0.4234551139739826,0.7372578479891295,0.12885737883854684,-0.12760615078476442,-0.02106529204966477,0.7592385640896675,-0.736311113618571,-0.4234551139739826,-0.04241010240522003,0.17185499556109507,-0.06373662902854216,-0.5073057591164345,-0.36036802408587215,3.251714214631556,-0.191309831206804,0.4096172898409424,2.6638687791403814,0.19338072765197223
3,430
Regulated necrosis
7
16
2.487878
0.012851
O00560,O75955,Q16543,Q8WUX9,Q14254,P09429,P07900
Processes and pathways
Reactome Pathways
msigdb_reactome
154,377,340,537,221,465,314
154,1979,377,2302,314,465,533,1553,995,2175,1176,221,340,2661,537,1734
1.7656129496664057,-0.23368633339360326,1.0687484169607406,-0.4234551139739826,1.2024003828056788,0.9356966299859146,0.8473319171085857,0.04307848903912287,0.4096172898409424,-0.3393012744587857,0.2796623627116229,1.4714808810674698,1.1577834161963467,-0.6325077598761806,0.8473319171085857,-0.06373662902854216
3,430
Aurka activation by tpx2
13
39
2.486615
0.012897
P62258,Q9BV73,O15078,O94927,O95613,Q14203,P41208,P61981,O75330,Q99996,O75935,Q13561,P07900
Processes and pathways
Reactome Pathways
msigdb_reactome
67,309,173,175,515,188,19,427,424,387,443,415,314
1779,173,821,424,443,175,515,3005,1132,543,988,314,1632,1879,968,19,1079,2485,1141,427,67,2991,2139,1406,415,1526,188,833,1484,696,1216,1822,886,2123,387,309,1863,3246,2668
-0.10633468895957496,1.6748229295823038,0.5402049440683143,1.0021471184507622,0.9799801607699364,1.6748229295823038,0.8693977289284917,-0.9629504767360699,0.3012772815040069,0.8252830651235218,0.4096172898409424,1.2024003828056788,-0.02106529204966477,-0.17009375816547115,0.43133814681776855,3.204350628748325,0.34456029993080256,-0.5282207546911941,0.3012772815040069,1.0021471184507622,2.431327036159296,-0.942446145812876,-0.31821572844136564,0.12885737883854684,1.0243308327237213,0.06449608277835585,1.6068977874861423,0.5402049440683143,0.0859317852989234,0.6495063733352072,0.2580652147528089,-0.12760615078476442,0.4966058497171867,-0.2971114238181862,1.0687484169607406,1.2247336356763627,-0.14885918591010985,-1.3687716700453372,-0.6325077598761806
3,430
Regulation of cell shape
10
32
2.482255
0.013055
P09493,Q9UEE9,P35580,O75844,Q7Z406,O75400,P15311,P35241,P46108,P26038
Processes and pathways
GO Biological process
msigdb_gobp
3,36,255,322,117,365,87,25,282,90
1949,846,2987,365,322,3141,583,3349,3,2404,87,90,25,444,255,282,744,2200,2991,2108,1343,774,1754,1349,117,2217,3180,809,2787,36,927,842
-0.21250736851480986,0.518396688704323,-0.942446145812876,1.0909822301776992,1.1800836337709497,-1.1465830158056964,0.7812363588966038,-1.7662056912720292,4.649741438376801,-0.4863716580376144,2.177283285595381,2.131292988821414,3.0861951345931513,0.9799801607699364,1.359078200582899,1.269449542990556,0.6057338953933035,-0.36036802408587215,-0.942446145812876,-0.2971114238181862,0.17185499556109507,0.5838735785783277,-0.08504483643208101,0.17185499556109507,1.993693905134758,-0.36036802408587215,-1.2074277428722162,0.5620305844376072,-0.736311113618571,2.8509790683742646,0.4748324586170831,0.5402049440683143
3,430
Negative regulation of protein containing complex assembly
18
43
2.481103
0.013098
Q13813,Q15691,Q01082,P45880,P04062,O15020,P16949,Q9NUQ9,Q6IBS0,Q9UBN7,Q02790,P52907,Q96QK1,P35241,Q9UBB9,Q9NYL9,P09429,P50542
Processes and pathways
GO Biological process
msigdb_gobp
119,696,256,603,167,634,8,630,143,246,368,301,507,25,612,611,465,691
1161,634,709,1626,1103,167,1132,3210,465,8,1843,2799,25,1670,2272,3077,603,991,1672,691,301,2562,2843,256,368,1598,2204,119,2381,696,143,2312,2572,507,3329,1424,1313,630,611,1835,612,246,1196
0.2796623627116229,0.7152942406319166,0.6276115039211269,-0.02106529204966477,0.3229099381780773,1.7201861433390337,0.3012772815040069,-1.2882658134684348,0.9356966299859146,4.186646783930239,-0.14885918591010985,-0.7570132956764223,3.0861951345931513,-0.04241010240522003,-0.40244498209708657,-1.0447671183808418,0.7592385640896675,0.4096172898409424,-0.04241010240522003,0.6495063733352072,1.2247336356763627,-0.569993271061387,-0.7983588379042941,1.359078200582899,1.0909822301776992,0.0002977667180233936,-0.36036802408587215,1.9708151956500113,-0.4654184907728244,0.6495063733352072,1.8338719570141517,-0.4234551139739826,-0.569993271061387,0.8914804711800896,-1.66765560705382,0.12885737883854684,0.19338072765197223,0.7372578479891295,0.7592385640896675,-0.12760615078476442,0.7592385640896675,1.4039905186201218,0.2796623627116229
3,430
Mitochondrial atp synthesis coupled proton transport
7
10
2.474956
0.013325
O75964,P06576,P24539,Q9UJZ1,P36542,P25705,P56385
Processes and pathways
GO Biological process
msigdb_gobp
2,40,109,390,281,501,412
793,2,40,109,501,281,521,3294,412,390
0.5620305844376072,5.167196520160504,2.8041124444238252,2.0394981091593998,0.8914804711800896,1.269449542990556,0.8693977289284917,-1.548678875208257,1.0243308327237213,1.0687484169607406
3,430
Positive regulation of cellular amide metabolic process
17
66
2.47341
0.013383
P63241,O15514,P60228,P42345,Q92552,P67809,P08670,Q7L0Y3,O60506,Q9Y2R0,Q9NWS8,P98179,Q07021,Q567V2,Q14103,P78344,P42574
Processes and pathways
GO Biological process
msigdb_gobp
413,163,262,233,609,235,11,628,479,49,18,536,217,431,566,283,533
1161,1949,1950,163,479,1102,1163,2557,11,618,1516,1631,2167,233,533,2656,2675,3094,2066,1674,3201,262,1525,744,3222,1963,413,235,283,1374,536,2110,3113,1299,1598,1209,217,2658,1641,1114,1997,1407,2310,566,2781,431,2864,1348,2313,628,1416,1823,1647,609,2786,2321,1698,1357,1730,2460,2222,18,1944,1008,49,1327
0.2796623627116229,-0.21250736851480986,-0.21250736851480986,1.742891610000047,0.9135801145844248,0.3229099381780773,0.2796623627116229,-0.569993271061387,3.824533083456319,0.7372578479891295,0.06449608277835585,-0.02106529204966477,-0.3393012744587857,1.4264710812485106,0.8473319171085857,-0.6325077598761806,-0.6533072855099272,-1.0651708848393058,-0.2759883981888322,-0.04241010240522003,-1.2680873203022425,1.3366464985559088,0.06449608277835585,0.6057338953933035,-1.3084235436014806,-0.21250736851480986,1.0243308327237213,1.4264710812485106,1.269449542990556,0.15034720133396523,0.8473319171085857,-0.2971114238181862,-1.085554403485646,0.19338072765197223,0.0002977667180233936,0.2580652147528089,1.4940100655111697,-0.6325077598761806,-0.02106529204966477,0.3229099381780773,-0.23368633339360326,0.12885737883854684,-0.4234551139739826,0.8032512025014997,-0.736311113618571,1.0021471184507622,-0.8190021137923701,0.17185499556109507,-0.4234551139739826,0.7372578479891295,0.12885737883854684,-0.12760615078476442,-0.02106529204966477,0.7592385640896675,-0.736311113618571,-0.4234551139739826,-0.04241010240522003,0.17185499556109507,-0.06373662902854216,-0.5073057591164345,-0.36036802408587215,3.251714214631556,-0.191309831206804,0.4096172898409424,2.6638687791403814,0.19338072765197223
3,430
Tetratricopeptide-like helical domain superfamily [IPR011990]
47
94
2.471523
0.013454
Q96DB5,O43242,Q9NSK0,Q6DKK2,Q13451,O15460,Q13042,Q12996,Q13535,A0AVF1,P31948,Q96EK5,Q9BXJ9,P54920,Q15020,O14579,O76094,P50542,Q15006,O75153,Q92791,P49321,Q8IYR2,O75127,Q6P2P2,Q9UJX2,Q15008,Q6ZXV5,Q00610,Q92552,P61201,Q9Y6X3,Q96EY7,P42345,O00231,O94826,Q32P28,O00170,Q13325,O75718,Q9Y262,Q9BZJ0,Q02790,P42704,Q14CX7,Q9HCS7,Q6P3X3
Sequence
InterPro Superfamily
interpro_homologous_superfamily
527,375,402,267,398,391,156,909,292,790,290,548,439,302,834,930,557,691,189,66,460,324,973,708,473,871,470,351,745,609,348,1012,1003,233,356,987,370,984,487,732,894,245,368,739,242,389,651
790,984,356,1366,930,1979,391,375,1231,708,66,732,1129,557,987,1070,2198,1105,1958,290,2234,233,739,324,1844,691,2595,302,348,745,368,1341,1599,2709,909,156,1997,487,398,292,3249,1889,242,189,470,834,1051,370,2783,267,473,651,1217,1304,351,2385,1249,1418,973,609,460,3084,3118,527,548,1003,2148,1035,2459,1765,1827,439,245,1120,1155,2663,3310,1317,389,402,2901,1618,1866,871,2264,1158,1734,2619,894,2056,2939,2512,1738,1012
0.5620305844376072,0.4096172898409424,1.1132326864910351,0.15034720133396523,0.45307654705381356,-0.23368633339360326,1.0465312750378557,1.0687484169607406,0.23648587072936555,0.6276115039211269,2.431327036159296,0.6057338953933035,0.3012772815040069,0.8032512025014997,0.4096172898409424,0.34456029993080256,-0.36036802408587215,0.3229099381780773,-0.21250736851480986,1.2470833648713042,-0.38141593935161383,1.4264710812485106,0.6057338953933035,1.1800836337709497,-0.14885918591010985,0.6495063733352072,-0.5908507122210328,1.2247336356763627,1.1354997578192654,0.6057338953933035,1.0909822301776992,0.17185499556109507,0.0002977667180233936,-0.6740874247602239,0.4748324586170831,1.7656129496664057,-0.23368633339360326,0.9135801145844248,1.0465312750378557,1.2470833648713042,-1.3888458608945973,-0.17009375816547115,1.4039905186201218,1.6068977874861423,0.9356966299859146,0.5402049440683143,0.3662283341069291,1.0909822301776992,-0.736311113618571,1.314231136956651,0.9356966299859146,0.7152942406319166,0.2580652147528089,0.19338072765197223,1.1354997578192654,-0.4654184907728244,0.23648587072936555,0.12885737883854684,0.43133814681776855,0.7592385640896675,0.9578299883515244,-1.0447671183808418,-1.085554403485646,0.8693977289284917,0.8252830651235218,0.4096172898409424,-0.31821572844136564,0.387914008197925,-0.5073057591164345,-0.08504483643208101,-0.12760615078476442,1.0021471184507622,1.4039905186201218,0.3229099381780773,0.3012772815040069,-0.6325077598761806,-1.5884240069937268,0.19338072765197223,1.0687484169607406,1.0465312750378557,-0.8396256696385406,0.0002977667180233936,-0.14885918591010985,0.518396688704323,-0.38141593935161383,0.3012772815040069,-0.06373662902854216,-0.5908507122210328,0.4966058497171867,-0.254846688969337,-0.8808134501833325,-0.5282207546911941,-0.06373662902854216,0.4096172898409424
3,430
Negative regulation of actin filament depolymerization
6
18
2.451574
0.014223
Q01082,Q6IBS0,P52907,Q13813,Q9NYL9,P35241
Processes and pathways
GO Biological process
msigdb_gobp
256,143,301,119,611,25
634,1843,25,1670,2272,991,1672,301,2562,256,2204,119,143,2312,1424,611,1196,1620
0.7152942406319166,-0.14885918591010985,3.0861951345931513,-0.04241010240522003,-0.40244498209708657,0.4096172898409424,-0.04241010240522003,1.2247336356763627,-0.569993271061387,1.359078200582899,-0.36036802408587215,1.9708151956500113,1.8338719570141517,-0.4234551139739826,0.12885737883854684,0.7592385640896675,0.2796623627116229,0.0002977667180233936
3,430
Regulation of macroautophagy
19
61
2.450806
0.014254
O15118,P54646,P42574,Q9Y5K8,P12235,P04062,Q96A65,Q9UNH7,Q93050,P09601,O15269,Q9Y5X3,P42345,Q14457,Q9UPT5,Q9UBN7,Q96QK1,Q15382,P21796
Processes and pathways
GO Biological process
msigdb_gobp
265,151,533,288,406,167,307,186,461,71,450,478,233,358,113,246,507,506,249
2298,265,450,1162,3138,1128,1547,1164,1235,167,2402,1987,2302,2331,1955,1549,71,406,1632,1879,3023,3076,249,1169,3331,1137,1791,233,533,690,561,151,1637,1719,1639,358,1345,506,1348,1855,780,1252,921,461,307,3085,507,1826,2322,1861,2815,3191,246,1622,186,113,1010,2986,727,288,478
-0.4234551139739826,1.314231136956651,0.9578299883515244,0.2796623627116229,-1.1465830158056964,0.3012772815040069,0.04307848903912287,0.2796623627116229,0.23648587072936555,1.7201861433390337,-0.4863716580376144,-0.23368633339360326,-0.4234551139739826,-0.44444629644309747,-0.21250736851480986,0.04307848903912287,2.40815588672373,1.0243308327237213,-0.02106529204966477,-0.17009375816547115,-0.9834347839005033,-1.0447671183808418,1.3815262161857498,0.2796623627116229,-1.6874093080839918,0.3012772815040069,-0.10633468895957496,1.4264710812485106,0.8473319171085857,0.6495063733352072,0.8032512025014997,1.7883501373217856,-0.02106529204966477,-0.06373662902854216,-0.02106529204966477,1.1132326864910351,0.17185499556109507,0.8914804711800896,0.17185499556109507,-0.14885918591010985,0.5838735785783277,0.23648587072936555,0.4748324586170831,0.9578299883515244,1.2247336356763627,-1.0447671183808418,0.8914804711800896,-0.12760615078476442,-0.4234551139739826,-0.14885918591010985,-0.7570132956764223,-1.227668237248389,1.4039905186201218,0.0002977667180233936,1.65216523300499,2.0165882176348306,0.4096172898409424,-0.9219218352181526,0.6276115039211269,1.269449542990556,0.9356966299859146
3,430
Spectrin repeat [IPR002017]
7
11
2.446678
0.014418
Q01082,O43707,O75962,P46939,Q9UPN3,Q13813,P12814
Sequence
InterPro Repeat
interpro_repeat
256,289,106,425,321,119,466
634,289,106,466,2437,425,256,2240,119,1149,321
0.7152942406319166,1.2470833648713042,2.0394981091593998,0.9356966299859146,-0.5073057591164345,1.0021471184507622,1.359078200582899,-0.38141593935161383,1.9708151956500113,0.3012772815040069,1.2024003828056788
3,430
Cytochrome complex
8
18
2.441338
0.014633
P14406,P00403,P08574,P22695,P13073,P14854,P14927,Q9UDW1
Localization
GO Cellular component
msigdb_gocc
560,558,223,232,108,484,14,579
2858,1367,558,223,1663,1664,108,560,484,14,3211,659,232,1473,1713,2635,579,1590
-0.8190021137923701,0.15034720133396523,0.8032512025014997,1.448967877539575,-0.04241010240522003,-0.04241010240522003,2.0394981091593998,0.8032512025014997,0.9135801145844248,3.537101859755954,-1.2882658134684348,0.6933477721843095,1.4264710812485106,0.0859317852989234,-0.06373662902854216,-0.6116888886017858,0.8032512025014997,0.02167903874393584
3,430
Nucleoside triphosphate biosynthetic process
11
34
2.440346
0.014673
O75964,P48047,P06576,P55263,P24539,Q05682,Q9UJZ1,P36542,P25705,P04818,P56385
Processes and pathways
GO Biological process
msigdb_gobp
2,521,40,10,109,204,390,281,501,60,412
1985,793,2,558,3153,3141,60,40,3055,1262,2826,3313,1468,1134,109,501,1203,1666,1399,281,1791,521,882,10,3294,412,204,1801,2866,1830,1225,2546,390,1285
-0.23368633339360326,0.5620305844376072,5.167196520160504,0.8032512025014997,-1.1668850851929853,-1.1465830158056964,2.500931367431874,2.8041124444238252,-1.024343149410197,0.21492436389411237,-0.7776958844485033,-1.6082643193752386,0.0859317852989234,0.3012772815040069,2.0394981091593998,0.8914804711800896,0.2580652147528089,-0.04241010240522003,0.12885737883854684,1.269449542990556,-0.10633468895957496,0.8693977289284917,0.4966058497171867,3.993132131516715,-1.548678875208257,1.0243308327237213,1.5391168723820783,-0.10633468895957496,-0.8190021137923701,-0.12760615078476442,0.2580652147528089,-0.5491166052451673,1.0687484169607406,0.21492436389411237
3,430
Metalloendopeptidase activity
9
14
2.439244
0.014718
Q9BYT8,Q92905,Q99797,P22695,P14735,O75844,P42892,Q10713,Q96TA2
Functions
GO Molecular function
msigdb_gomf
759,490,438,232,796,322,208,414,187
2159,2300,322,796,232,208,1816,414,1684,490,187,438,759,895
-0.3393012744587857,-0.4234551139739826,1.1800836337709497,0.5620305844376072,1.4264710812485106,1.5165554046538223,-0.12760615078476442,1.0243308327237213,-0.04241010240522003,0.9135801145844248,1.6295235104710366,1.0021471184507622,0.6057338953933035,0.4966058497171867
3,430
Respiratory electron transport
23
54
2.434722
0.014903
O43676,P51970,P14927,O75306,Q16718,P20674,O00217,Q9BQ95,Q9P0J0,Q9UDW1,Q12931,P00403,Q9Y6M9,Q8N183,O75489,Q9NPL8,Q86Y39,P08574,P22695,P13073,P14854,P42704,P03886
Processes and pathways
Reactome Pathways
msigdb_reactome
4,397,14,514,146,659,656,687,45,579,694,558,449,68,710,476,352,223,232,108,484,739,500
656,2858,1367,4,3021,2025,2587,514,2369,1435,710,1234,1514,3175,2060,1515,558,500,223,1663,1664,108,2884,484,14,3211,3142,659,2332,232,2886,2483,1473,2946,739,1713,3124,397,694,1601,146,1180,1821,352,68,1058,687,3101,1191,476,813,45,579,449
0.6933477721843095,-0.8190021137923701,0.15034720133396523,4.551842722059264,-0.9834347839005033,-0.254846688969337,-0.5908507122210328,0.8693977289284917,-0.4654184907728244,0.10738556209941592,0.6276115039211269,0.23648587072936555,0.06449608277835585,-1.2074277428722162,-0.2759883981888322,0.06449608277835585,0.8032512025014997,0.8914804711800896,1.448967877539575,-0.04241010240522003,-0.04241010240522003,2.0394981091593998,-0.8396256696385406,0.9135801145844248,3.537101859755954,-1.2882658134684348,-1.1465830158056964,0.6933477721843095,-0.44444629644309747,1.4264710812485106,-0.8396256696385406,-0.5282207546911941,0.0859317852989234,-0.9013775888027895,0.6057338953933035,-0.06373662902854216,-1.1059176287710073,1.0465312750378557,0.6495063733352072,0.0002977667180233936,1.8111031480459492,0.2796623627116229,-0.12760615078476442,1.1354997578192654,2.431327036159296,0.3662283341069291,0.6714184729428473,-1.0651708848393058,0.2796623627116229,0.9356966299859146,0.5620305844376072,2.7105571292304815,0.8032512025014997,0.9799801607699364
3,430
Positive regulation of chromosome organization
14
49
2.425466
0.015289
P78371,Q13535,Q04837,Q92878,Q14980,P12270,Q9NTJ3,Q15554,O95347,Q14103,Q13315,P23246,Q96HR8,Q96MF7
Processes and pathways
GO Biological process
msigdb_gobp
446,292,168,268,456,107,440,209,366,566,661,27,386,28
2671,1434,2196,2769,366,2370,2480,107,850,1551,1597,27,824,1633,1169,1439,2829,738,938,1521,679,1673,1845,1815,446,168,1681,661,292,566,456,2342,1483,1925,209,268,1150,386,28,2576,1610,1093,1356,1424,2324,2222,440,2397,1806
-0.6533072855099272,0.10738556209941592,-0.36036802408587215,-0.736311113618571,1.0909822301776992,-0.4654184907728244,-0.5282207546911941,2.0394981091593998,0.518396688704323,0.04307848903912287,0.0002977667180233936,2.9919327835623593,0.5402049440683143,-0.02106529204966477,0.2796623627116229,0.10738556209941592,-0.7776958844485033,0.6057338953933035,0.45307654705381356,0.06449608277835585,0.6714184729428473,-0.04241010240522003,-0.14885918591010985,-0.12760615078476442,0.9799801607699364,1.7201861433390337,-0.04241010240522003,0.6933477721843095,1.2470833648713042,0.8032512025014997,0.9578299883515244,-0.44444629644309747,0.0859317852989234,-0.191309831206804,1.5165554046538223,1.314231136956651,0.3012772815040069,1.0687484169607406,2.9919327835623593,-0.569993271061387,0.0002977667180233936,0.34456029993080256,0.17185499556109507,0.12885737883854684,-0.4234551139739826,-0.36036802408587215,1.0021471184507622,-0.4654184907728244,-0.10633468895957496
3,430
Insulin processing
6
9
2.41742
0.015631
Q96KP1,Q96A65,P33176,Q9UPT5,O60645,Q8IYI6
Processes and pathways
Reactome Pathways
msigdb_reactome
492,307,110,113,423,780
844,423,110,780,307,1606,492,113,1737
0.518396688704323,1.0021471184507622,2.0165882176348306,0.5838735785783277,1.2247336356763627,0.0002977667180233936,0.9135801145844248,2.0165882176348306,-0.06373662902854216
3,430
Proton transporting atp synthase complex
6
10
2.406943
0.016087
O75964,P06576,P24539,P36542,P25705,P56385
Localization
GO Cellular component
msigdb_gocc
2,40,109,281,501,412
793,2,40,109,501,281,521,3294,412,1763
0.5620305844376072,5.167196520160504,2.8041124444238252,2.0394981091593998,0.8914804711800896,1.269449542990556,0.8693977289284917,-1.548678875208257,1.0243308327237213,-0.08504483643208101
3,430
Proton transporting atp synthase activity rotational mechanism
6
10
2.400967
0.016352
O75964,P06576,P24539,P36542,P25705,P56385
Functions
GO Molecular function
msigdb_gomf
2,40,109,281,501,412
793,2,40,109,501,281,1791,521,3294,412
0.5620305844376072,5.167196520160504,2.8041124444238252,2.0394981091593998,0.8914804711800896,1.269449542990556,-0.10633468895957496,0.8693977289284917,-1.548678875208257,1.0243308327237213
3,430
Proton channel activity
6
10
2.400967
0.016352
O75964,P06576,P24539,P36542,P25705,P56385
Functions
GO Molecular function
msigdb_gomf
2,40,109,281,501,412
793,2,40,109,501,281,1791,521,3294,412
0.5620305844376072,5.167196520160504,2.8041124444238252,2.0394981091593998,0.8914804711800896,1.269449542990556,-0.10633468895957496,0.8693977289284917,-1.548678875208257,1.0243308327237213
3,430
Active transmembrane transporter activity
21
74
2.390788
0.016812
O43676,O95202,P51970,O75306,Q16718,P20674,Q9Y5K8,P12235,P06576,Q9P0J0,P08183,Q9UDW1,Q9UBX3,P00403,Q9Y6M9,Q9HD20,P16615,P08574,P13073,P14854,P03886
Functions
GO Molecular function
msigdb_gomf
4,638,397,514,146,659,288,406,40,45,177,579,320,558,449,227,602,223,108,484,500
656,2858,763,1595,4,3021,1575,2587,514,2369,1435,710,1514,3175,638,2060,1515,558,500,1261,2331,40,177,1916,223,1664,406,1811,108,484,602,3142,852,659,3023,3076,1919,1745,2886,1473,1137,1791,1713,3124,2274,397,2594,2067,829,1637,2488,1242,2173,1112,2413,2754,2143,146,1180,2635,1419,3160,2014,2814,227,2390,1653,45,320,579,1622,288,896,449
0.6933477721843095,-0.8190021137923701,0.5838735785783277,0.0002977667180233936,4.551842722059264,-0.9834347839005033,0.02167903874393584,-0.5908507122210328,0.8693977289284917,-0.4654184907728244,0.10738556209941592,0.6276115039211269,0.06449608277835585,-1.2074277428722162,0.7152942406319166,-0.2759883981888322,0.06449608277835585,0.8032512025014997,0.8914804711800896,0.21492436389411237,-0.44444629644309747,2.8041124444238252,1.6748229295823038,-0.191309831206804,1.448967877539575,-0.04241010240522003,1.0243308327237213,-0.12760615078476442,2.0394981091593998,0.9135801145844248,0.7592385640896675,-1.1465830158056964,0.518396688704323,0.6933477721843095,-0.9834347839005033,-1.0447671183808418,-0.191309831206804,-0.08504483643208101,-0.8396256696385406,0.0859317852989234,0.3012772815040069,-0.10633468895957496,-0.06373662902854216,-1.1059176287710073,-0.40244498209708657,1.0465312750378557,-0.5908507122210328,-0.2759883981888322,0.5402049440683143,-0.02106529204966477,-0.5282207546911941,0.23648587072936555,-0.3393012744587857,0.3229099381780773,-0.4863716580376144,-0.7155893800863863,-0.31821572844136564,1.8111031480459492,0.2796623627116229,-0.6116888886017858,0.12885737883854684,-1.1668850851929853,-0.23368633339360326,-0.7570132956764223,1.448967877539575,-0.4654184907728244,-0.02106529204966477,2.7105571292304815,1.2024003828056788,0.8032512025014997,0.0002977667180233936,1.269449542990556,0.4966058497171867,0.9799801607699364
3,430
Tetrapyrrole binding
11
18
2.374839
0.017557
Q16850,P08574,P09601,P30519,O15173,Q9H7Z7,P53701,O43169,P22033,Q9Y5Z4,O00264
Functions
GO Molecular function
msigdb_gomf
226,223,71,43,672,373,586,115,736,94,95
95,672,115,223,71,736,43,586,226,776,2635,3147,2870,1187,373,2544,2511,94
2.108321019317115,0.6714184729428473,1.993693905134758,1.448967877539575,2.40815588672373,0.6057338953933035,2.7105571292304815,0.7812363588966038,1.448967877539575,0.5838735785783277,-0.6116888886017858,-1.1465830158056964,-0.8190021137923701,0.2796623627116229,1.0909822301776992,-0.5491166052451673,-0.5282207546911941,2.131292988821414
3,430
Oxidoreduction driven active transmembrane transporter activity
14
32
2.372342
0.017676
P00403,Q9Y6M9,O43676,P08574,P51970,P13073,P14854,Q9P0J0,O75306,Q9UDW1,Q16718,P03886,P20674,O00217
Functions
GO Molecular function
msigdb_gomf
558,449,4,223,397,108,484,45,514,579,146,500,659,656
656,2858,4,3021,2587,514,2369,1435,710,1514,3175,2060,1515,558,500,223,1664,108,484,3142,659,2886,1473,1713,3124,397,146,1180,2635,45,579,449
0.6933477721843095,-0.8190021137923701,4.551842722059264,-0.9834347839005033,-0.5908507122210328,0.8693977289284917,-0.4654184907728244,0.10738556209941592,0.6276115039211269,0.06449608277835585,-1.2074277428722162,-0.2759883981888322,0.06449608277835585,0.8032512025014997,0.8914804711800896,1.448967877539575,-0.04241010240522003,2.0394981091593998,0.9135801145844248,-1.1465830158056964,0.6933477721843095,-0.8396256696385406,0.0859317852989234,-0.06373662902854216,-1.1059176287710073,1.0465312750378557,1.8111031480459492,0.2796623627116229,-0.6116888886017858,2.7105571292304815,0.8032512025014997,0.9799801607699364
3,430
chaperone
16
69
2.370284
0.017774
Q99426,Q15006,Q8N183,P30533,O75937,P49321,Q13451,Q96BP3,Q9Y2R0,Q02790,Q8WXX5,Q16543,Q9NWM8,P78318,Q9Y2G8,Q14203
Functions
Panther Protein class
panther_protein_class
160,189,68,99,37,324,398,341,49,368,181,340,421,216,122,188
984,3166,2366,2095,3052,1625,792,37,675,1809,935,2557,1017,1331,3006,1168,3293,1812,826,3059,2674,99,1440,1669,2920,879,324,2069,216,800,368,1599,2341,398,188,3249,189,1028,943,2681,340,1686,2635,1090,1561,68,1724,974,181,3068,341,2424,949,160,436,629,1765,2790,1313,2852,1319,421,597,598,2964,1572,122,49,789
0.4096172898409424,-1.1871666764907194,-0.4654184907728244,-0.2971114238181862,-1.024343149410197,-0.02106529204966477,0.5620305844376072,2.8275383601959625,0.6714184729428473,-0.12760615078476442,0.45307654705381356,-0.569993271061387,0.387914008197925,0.17185499556109507,-0.9629504767360699,0.2796623627116229,-1.548678875208257,-0.12760615078476442,0.5402049440683143,-1.024343149410197,-0.6533072855099272,2.0853645337676863,0.10738556209941592,-0.04241010240522003,-0.8808134501833325,0.4966058497171867,1.1800836337709497,-0.2759883981888322,1.4940100655111697,0.5620305844376072,1.0909822301776992,0.0002977667180233936,-0.44444629644309747,1.0465312750378557,1.6068977874861423,-1.3888458608945973,1.6068977874861423,0.387914008197925,0.45307654705381356,-0.6533072855099272,1.1577834161963467,-0.04241010240522003,-0.6116888886017858,0.34456029993080256,0.04307848903912287,2.431327036159296,-0.06373662902854216,0.43133814681776855,1.6748229295823038,-1.024343149410197,1.1577834161963467,-0.4863716580376144,0.45307654705381356,1.7656129496664057,1.0021471184507622,0.7372578479891295,-0.08504483643208101,-0.736311113618571,0.19338072765197223,-0.7983588379042941,0.19338072765197223,1.0243308327237213,0.7812363588966038,0.7812363588966038,-0.9013775888027895,0.04307848903912287,1.9708151956500113,2.6638687791403814,0.5838735785783277
3,430
Primary active transmembrane transporter activity
19
56
2.369978
0.017789
O43676,P51970,O75306,Q16718,P20674,O00217,Q9Y5K8,P06576,Q9P0J0,P08183,Q9UDW1,P00403,Q9Y6M9,Q9HD20,P16615,P08574,P13073,P14854,P03886
Functions
GO Molecular function
msigdb_gomf
4,397,514,146,659,656,288,40,45,177,579,558,449,227,602,223,108,484,500
656,2858,763,1595,4,3021,1575,2587,514,2369,1435,710,1514,3175,2060,1515,558,500,1261,40,177,223,1664,108,484,602,3142,852,659,3023,3076,1919,1745,2886,1473,1137,1791,1713,3124,2274,397,1637,2173,1112,2754,146,1180,2635,227,2390,1653,45,579,1622,288,449
0.6933477721843095,-0.8190021137923701,0.5838735785783277,0.0002977667180233936,4.551842722059264,-0.9834347839005033,0.02167903874393584,-0.5908507122210328,0.8693977289284917,-0.4654184907728244,0.10738556209941592,0.6276115039211269,0.06449608277835585,-1.2074277428722162,-0.2759883981888322,0.06449608277835585,0.8032512025014997,0.8914804711800896,0.21492436389411237,2.8041124444238252,1.6748229295823038,1.448967877539575,-0.04241010240522003,2.0394981091593998,0.9135801145844248,0.7592385640896675,-1.1465830158056964,0.518396688704323,0.6933477721843095,-0.9834347839005033,-1.0447671183808418,-0.191309831206804,-0.08504483643208101,-0.8396256696385406,0.0859317852989234,0.3012772815040069,-0.10633468895957496,-0.06373662902854216,-1.1059176287710073,-0.40244498209708657,1.0465312750378557,-0.02106529204966477,-0.3393012744587857,0.3229099381780773,-0.7155893800863863,1.8111031480459492,0.2796623627116229,-0.6116888886017858,1.448967877539575,-0.4654184907728244,-0.02106529204966477,2.7105571292304815,0.8032512025014997,0.0002977667180233936,1.269449542990556,0.9799801607699364
3,430
Recruitment of mitotic centrosome proteins and complexes
12
40
2.359605
0.018294
P62258,Q9BV73,O15078,O94927,O95613,Q14203,P41208,P61981,Q99996,O75935,Q13561,P07900
Processes and pathways
Reactome Pathways
msigdb_reactome
67,309,173,175,515,188,19,427,387,443,415,314
173,821,443,175,515,3005,1132,543,988,314,1632,1879,2517,968,19,1079,2485,1141,427,67,2991,2139,1406,415,1526,188,833,1484,696,1216,1822,886,1585,2123,387,1499,309,1863,3246,1285
1.6748229295823038,0.5402049440683143,0.9799801607699364,1.6748229295823038,0.8693977289284917,-0.9629504767360699,0.3012772815040069,0.8252830651235218,0.4096172898409424,1.2024003828056788,-0.02106529204966477,-0.17009375816547115,-0.5491166052451673,0.43133814681776855,3.204350628748325,0.34456029993080256,-0.5282207546911941,0.3012772815040069,1.0021471184507622,2.431327036159296,-0.942446145812876,-0.31821572844136564,0.12885737883854684,1.0243308327237213,0.06449608277835585,1.6068977874861423,0.5402049440683143,0.0859317852989234,0.6495063733352072,0.2580652147528089,-0.12760615078476442,0.4966058497171867,0.02167903874393584,-0.2971114238181862,1.0687484169607406,0.0859317852989234,1.2247336356763627,-0.14885918591010985,-1.3687716700453372,0.21492436389411237
3,430
Chronic constipation
9
28
2.352765
0.018634
Q03252,P04062,P20700,O75962,Q7LGA3,Q96QK1,P78318,P63241,Q16851
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
34,167,77,106,144,507,216,413,350
556,792,106,167,1629,77,3079,829,1025,3042,413,216,34,1299,1851,350,2601,144,2738,975,1897,3018,1649,2049,507,1313,1357,1862
0.8032512025014997,0.5620305844376072,2.0394981091593998,1.7201861433390337,-0.02106529204966477,2.3156233598343645,-1.0447671183808418,0.5402049440683143,0.387914008197925,-1.0038990229805613,1.0243308327237213,1.4940100655111697,2.8979047777720357,0.19338072765197223,-0.14885918591010985,1.1354997578192654,-0.5908507122210328,1.8338719570141517,-0.6948481366740377,0.43133814681776855,-0.17009375816547115,-0.9629504767360699,-0.02106529204966477,-0.254846688969337,0.8914804711800896,0.19338072765197223,0.17185499556109507,-0.14885918591010985
3,430
Hydrogen ion transport
8
19
2.343701
0.019093
O75964,Q93050,P06576,P56385,P24539,P36542,P25705,Q9Y5K8
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
2,461,40,412,109,281,501,288
793,2,40,3023,3076,109,501,281,1137,1791,521,3294,412,1637,2730,461,1622,727,288
0.5620305844376072,5.167196520160504,2.8041124444238252,-0.9834347839005033,-1.0447671183808418,2.0394981091593998,0.8914804711800896,1.269449542990556,0.3012772815040069,-0.10633468895957496,0.8693977289284917,-1.548678875208257,1.0243308327237213,-0.02106529204966477,-0.6948481366740377,0.9578299883515244,0.0002977667180233936,0.6276115039211269,1.269449542990556
3,430
Negative regulation of protein containing complex disassembly
6
29
2.32978
0.019818
Q13813,Q01082,Q6IBS0,Q9UBN7,P35241,Q92974
Processes and pathways
GO Biological process
msigdb_gobp
119,256,143,246,25,92
634,1574,1983,1843,25,1670,2272,2438,991,1672,301,2562,256,2204,119,143,2312,755,1822,2955,92,1424,2323,3191,611,246,1196,1620,2668
0.7152942406319166,0.02167903874393584,-0.23368633339360326,-0.14885918591010985,3.0861951345931513,-0.04241010240522003,-0.40244498209708657,-0.5073057591164345,0.4096172898409424,-0.04241010240522003,1.2247336356763627,-0.569993271061387,1.359078200582899,-0.36036802408587215,1.9708151956500113,1.8338719570141517,-0.4234551139739826,0.6057338953933035,-0.12760615078476442,-0.9013775888027895,2.131292988821414,0.12885737883854684,-0.4234551139739826,-1.227668237248389,0.7592385640896675,1.4039905186201218,0.2796623627116229,0.0002977667180233936,-0.6325077598761806
3,430
Formation of atp by chemiosmotic coupling
6
9
2.322769
0.020192
O75964,P06576,P24539,P36542,P25705,P56385
Processes and pathways
Reactome Pathways
msigdb_reactome
2,40,109,281,501,412
793,2,40,109,501,281,521,3294,412
0.5620305844376072,5.167196520160504,2.8041124444238252,2.0394981091593998,0.8914804711800896,1.269449542990556,0.8693977289284917,-1.548678875208257,1.0243308327237213
3,430
Nuclear periphery
14
62
2.31793
0.020453
Q15233,P08670,Q05682,P20700,P49454,P02545,P12270,O14929,Q8WXF1,Q9UQE7,O75400,Q99623,Q8N3U4,P23246
Localization
GO Cellular component
msigdb_gocc
128,11,204,77,396,46,107,105,123,182,365,89,383,27
105,1126,2860,3022,2671,2916,365,2701,46,2302,11,1917,1630,107,77,1597,27,2704,1666,1517,396,3248,3388,906,2376,1443,3201,716,1635,2277,2110,1598,204,1085,1802,662,456,128,1486,3158,668,383,920,123,2810,1568,2120,1497,2427,89,1533,3246,2156,2938,2092,182,1869,2965,841,1457,2857,1806
2.0394981091593998,0.3012772815040069,-0.8190021137923701,-0.9834347839005033,-0.6533072855099272,-0.8808134501833325,1.0909822301776992,-0.6740874247602239,2.6872054940154664,-0.4234551139739826,3.824533083456319,-0.191309831206804,-0.02106529204966477,2.0394981091593998,2.3156233598343645,0.0002977667180233936,2.9919327835623593,-0.6740874247602239,-0.04241010240522003,0.06449608277835585,1.0465312750378557,-1.3888458608945973,-2.269633127041858,0.4748324586170831,-0.4654184907728244,0.10738556209941592,-1.2680873203022425,0.6276115039211269,-0.02106529204966477,-0.40244498209708657,-0.2971114238181862,0.0002977667180233936,1.5391168723820783,0.34456029993080256,-0.10633468895957496,0.6933477721843095,0.9578299883515244,1.9022729265558864,0.0859317852989234,-1.1668850851929853,0.6933477721843095,1.0687484169607406,0.4748324586170831,1.9479521132618594,-0.7570132956764223,0.04307848903912287,-0.2971114238181862,0.0859317852989234,-0.4863716580376144,2.177283285595381,0.06449608277835585,-1.3687716700453372,-0.31821572844136564,-0.8808134501833325,-0.2759883981888322,1.6748229295823038,-0.14885918591010985,-0.9013775888027895,0.5402049440683143,0.10738556209941592,-0.7983588379042941,-0.10633468895957496
3,430
Proton transmembrane transport
15
40
2.317252
0.02049
Q99623,O75964,P48047,P12235,P08574,P06576,P13073,O43707,P24539,P14854,Q9UDW1,Q9UJZ1,P36542,P25705,P56385
Processes and pathways
GO Biological process
msigdb_gobp
89,2,521,406,223,40,108,289,109,484,579,390,281,501,412
2858,289,2587,793,2,558,1261,2331,40,223,1664,406,108,484,659,3023,3076,109,501,3059,1473,281,1137,1791,1713,521,3294,412,1637,2488,884,2635,3160,3329,89,2814,579,1621,1622,390
-0.8190021137923701,1.2470833648713042,-0.5908507122210328,0.5620305844376072,5.167196520160504,0.8032512025014997,0.21492436389411237,-0.44444629644309747,2.8041124444238252,1.448967877539575,-0.04241010240522003,1.0243308327237213,2.0394981091593998,0.9135801145844248,0.6933477721843095,-0.9834347839005033,-1.0447671183808418,2.0394981091593998,0.8914804711800896,-1.024343149410197,0.0859317852989234,1.269449542990556,0.3012772815040069,-0.10633468895957496,-0.06373662902854216,0.8693977289284917,-1.548678875208257,1.0243308327237213,-0.02106529204966477,-0.5282207546911941,0.4966058497171867,-0.6116888886017858,-1.1668850851929853,-1.66765560705382,2.177283285595381,-0.7570132956764223,0.8032512025014997,0.0002977667180233936,0.0002977667180233936,1.0687484169607406
3,430
Porphyrin containing compound metabolic process
7
17
2.304006
0.021222
Q9UII2,P09601,Q9BUT1,P30519,P53004,P36551,O00264
Processes and pathways
GO Biological process
msigdb_gobp
363,71,595,43,15,300,95
95,1575,601,1291,71,2134,43,2592,300,2752,15,2712,2635,595,2390,2876,363
2.108321019317115,0.02167903874393584,0.7592385640896675,0.19338072765197223,2.40815588672373,-0.31821572844136564,2.7105571292304815,-0.5908507122210328,1.2247336356763627,-0.7155893800863863,3.4655620728064624,-0.6740874247602239,-0.6116888886017858,0.7812363588966038,-0.4654184907728244,-0.8190021137923701,1.1132326864910351
3,430
Thin ribs
6
14
2.293377
0.021826
P50570,Q32P28,O75844,P02545,Q9UBN7,O75431
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
194,370,322,46,246,219
931,219,322,2161,2770,46,409,194,831,2681,370,246,1870,962
0.45307654705381356,1.4714808810674698,1.1800836337709497,-0.3393012744587857,-0.736311113618571,2.6872054940154664,1.0243308327237213,1.5842880896557086,0.5402049440683143,-0.6533072855099272,1.0909822301776992,1.4039905186201218,-0.14885918591010985,0.45307654705381356
3,430
Signaling by alk in cancer
10
37
2.287111
0.022189
P49589,Q8IWJ2,P12270,P33176,P06753,P67936,P18206,Q14203,P35579,P26038
Processes and pathways
Reactome Pathways
msigdb_reactome
503,263,107,110,176,16,393,188,444,90
531,2024,2839,2557,176,1236,107,393,2061,90,1265,1169,1439,1813,110,444,2168,503,1844,3079,1797,1082,3097,16,745,1341,1409,188,1054,2808,2315,263,1310,2053,2258,2224,840
0.8473319171085857,-0.254846688969337,-0.7983588379042941,-0.569993271061387,1.6748229295823038,0.23648587072936555,2.0394981091593998,1.0465312750378557,-0.2759883981888322,2.131292988821414,0.21492436389411237,0.2796623627116229,0.10738556209941592,-0.12760615078476442,2.0165882176348306,0.9799801607699364,-0.3393012744587857,0.8914804711800896,-0.14885918591010985,-1.0447671183808418,-0.10633468895957496,0.34456029993080256,-1.0651708848393058,3.4417439480452012,0.6057338953933035,0.17185499556109507,0.12885737883854684,1.6068977874861423,0.3662283341069291,-0.7570132956764223,-0.4234551139739826,1.3366464985559088,0.19338072765197223,-0.254846688969337,-0.38141593935161383,-0.36036802408587215,0.5402049440683143
3,430
Cargo trafficking to the periciliary membrane
10
20
2.284766
0.022327
Q96KP1,P49368,O00471,Q96A65,Q9UPT5,Q10713,O60645,Q8IYI6,P78371,A6NIH7
Processes and pathways
Reactome Pathways
msigdb_reactome
492,679,844,307,113,414,423,780,446,127
127,844,423,1912,1551,2591,2273,1521,679,1845,1815,2103,446,414,780,2002,307,492,956,113
1.9251046821425566,0.518396688704323,1.0021471184507622,-0.191309831206804,0.04307848903912287,-0.5908507122210328,-0.40244498209708657,0.06449608277835585,0.6714184729428473,-0.14885918591010985,-0.12760615078476442,-0.2971114238181862,0.9799801607699364,1.0243308327237213,0.5838735785783277,-0.23368633339360326,1.2247336356763627,0.9135801145844248,0.45307654705381356,2.0165882176348306
3,430
Ciliary basal body
7
24
2.283509
0.0224
Q8IUD2,P28070,Q9BV73,O15078,Q9UPT5,P41208,P15311
Localization
GO Cellular component
msigdb_gocc
134,41,309,173,113,19,87
790,173,821,1912,87,41,19,1714,396,2103,1484,696,777,134,3180,309,2873,1937,2225,815,3246,113,1456,2793
0.5620305844376072,1.6748229295823038,0.5402049440683143,-0.191309831206804,2.177283285595381,2.8041124444238252,3.204350628748325,-0.06373662902854216,1.0465312750378557,-0.2971114238181862,0.0859317852989234,0.6495063733352072,0.5838735785783277,1.8794568708577217,-1.2074277428722162,1.2247336356763627,-0.8190021137923701,-0.191309831206804,-0.36036802408587215,0.5620305844376072,-1.3687716700453372,2.0165882176348306,0.10738556209941592,-0.736311113618571
3,430
Cation transmembrane transporter activity
29
65
2.281506
0.022519
Q13423,O75964,P48047,O95202,Q6P4Q7,P36542,P20674,P56385,Q9Y5K8,P12235,P06576,O75947,Q9UDW1,Q93034,P00403,Q93050,P07355,Q9Y487,P55011,Q70HW3,Q9HD20,P20020,P08574,P16615,P13073,P24539,P14854,Q9Y6M7,P25705
Functions
GO Molecular function
msigdb_gomf
884,2,521,638,399,281,659,412,288,406,40,793,579,58,558,461,822,727,829,754,227,852,223,602,108,109,484,896,501
3375,1100,793,2,638,558,1261,2331,40,3176,822,1465,1916,223,1664,406,108,484,602,852,659,3023,3076,1919,109,501,1709,1473,281,1137,1791,1713,521,829,3294,412,1637,3302,2488,1639,884,2413,2143,913,399,754,2635,1419,58,461,3160,2121,3305,2014,1936,2814,2578,227,579,1622,1324,727,288,962,896
-2.0198432297961233,0.3229099381780773,0.5620305844376072,5.167196520160504,0.7152942406319166,0.8032512025014997,0.21492436389411237,-0.44444629644309747,2.8041124444238252,-1.2074277428722162,0.5402049440683143,0.0859317852989234,-0.191309831206804,1.448967877539575,-0.04241010240522003,1.0243308327237213,2.0394981091593998,0.9135801145844248,0.7592385640896675,0.518396688704323,0.6933477721843095,-0.9834347839005033,-1.0447671183808418,-0.191309831206804,2.0394981091593998,0.8914804711800896,-0.06373662902854216,0.0859317852989234,1.269449542990556,0.3012772815040069,-0.10633468895957496,-0.06373662902854216,0.8693977289284917,0.5402049440683143,-1.548678875208257,1.0243308327237213,-0.02106529204966477,-1.5685621747527327,-0.5282207546911941,-0.02106529204966477,0.4966058497171867,-0.4863716580376144,-0.31821572844136564,0.4748324586170831,1.0465312750378557,0.6057338953933035,-0.6116888886017858,0.12885737883854684,2.547409768053795,0.9578299883515244,-1.1668850851929853,-0.2971114238181862,-1.5685621747527327,-0.23368633339360326,-0.191309831206804,-0.7570132956764223,-0.569993271061387,1.448967877539575,0.8032512025014997,0.0002977667180233936,0.19338072765197223,0.6276115039211269,1.269449542990556,0.45307654705381356,0.4966058497171867
3,430
Cullin repeat-like-containing domain superfamily [IPR016159]
7
10
2.280762
0.022563
Q96MW5,Q13617,Q9UPT5,Q93034,Q13618,Q8IYI6,Q13619
Sequence
InterPro Superfamily
interpro_homologous_superfamily
447,717,113,58,749,780,832
1409,717,749,832,911,780,58,447,1257,113
0.12885737883854684,0.6276115039211269,0.6057338953933035,0.5402049440683143,0.4748324586170831,0.5838735785783277,2.547409768053795,0.9799801607699364,0.23648587072936555,2.0165882176348306
3,430
Copi mediated anterograde transport
26
57
2.280441
0.022582
Q01082,O15020,P24390,Q15363,Q13561,Q08379,Q13190,P48444,P54920,P52907,O14579,Q9UP83,Q8N6H7,P83436,O75935,Q14203,P46459,Q14204,Q96MW5,O60763,O43237,O43731,Q14789,P47755,O15498,Q13813
Processes and pathways
Reactome Pathways
msigdb_reactome
256,634,13,773,415,155,165,678,302,301,930,581,835,428,443,188,939,833,447,312,311,845,225,991,876,119
930,634,876,311,845,312,443,1130,1132,2591,13,1959,939,991,1672,678,992,301,2237,2038,302,1141,2444,1718,2991,2139,428,3357,256,155,2491,165,1406,415,119,1581,188,833,225,773,835,2604,2002,447,1827,1220,2083,2012,1358,2742,2360,1255,2091,581,1508,1703,1067
0.45307654705381356,0.7152942406319166,0.4966058497171867,1.2024003828056788,0.518396688704323,1.2024003828056788,0.9799801607699364,0.3012772815040069,0.3012772815040069,-0.5908507122210328,3.5848660368475693,-0.21250736851480986,0.45307654705381356,0.4096172898409424,-0.04241010240522003,0.6714184729428473,0.4096172898409424,1.2247336356763627,-0.38141593935161383,-0.254846688969337,1.2247336356763627,0.3012772815040069,-0.5073057591164345,-0.06373662902854216,-0.942446145812876,-0.31821572844136564,1.0021471184507622,-1.825072091951856,1.359078200582899,1.7656129496664057,-0.5282207546911941,1.742891610000047,0.12885737883854684,1.0243308327237213,1.9708151956500113,0.02167903874393584,1.6068977874861423,0.5402049440683143,1.448967877539575,0.5838735785783277,0.5402049440683143,-0.5908507122210328,-0.23368633339360326,0.9799801607699364,-0.12760615078476442,0.2580652147528089,-0.2759883981888322,-0.23368633339360326,0.17185499556109507,-0.6948481366740377,-0.44444629644309747,0.23648587072936555,-0.2759883981888322,0.8032512025014997,0.0859317852989234,-0.04241010240522003,0.3662283341069291
3,430
Transport to the golgi and subsequent modification
32
82
2.263194
0.023624
Q5JRA6,Q01082,O15020,Q8WVM8,O60512,P24390,Q15363,Q96PC5,Q13561,Q08379,Q8IUR0,Q13190,P48444,P54920,P52907,O60476,Q9UP83,Q8N6H7,O14579,P83436,O75935,Q14203,Q14204,Q96MW5,O60763,O43237,P49257,O43731,Q14789,O15498,Q13813,Q15436
Processes and pathways
Reactome Pathways
msigdb_reactome
525,256,634,921,140,13,773,29,415,155,805,165,678,302,301,51,581,835,930,428,443,188,833,447,312,311,562,845,225,876,119,649
2128,930,634,2821,876,311,845,51,140,312,1128,443,2161,2839,1130,1914,1202,3107,1132,2591,13,1959,939,991,1672,678,562,992,301,2237,2038,2596,302,1141,2444,1718,2991,2139,428,3357,256,155,2174,2491,165,1406,415,119,1581,188,833,225,773,649,1086,2345,525,805,835,2604,921,2002,1310,447,29,1827,1220,2083,2012,1358,2188,2742,2360,1255,2091,581,2055,1508,1703,3291,1067,1591
-0.31821572844136564,0.45307654705381356,0.7152942406319166,-0.7776958844485033,0.4966058497171867,1.2024003828056788,0.518396688704323,2.6172401968299104,1.8338719570141517,1.2024003828056788,0.3012772815040069,0.9799801607699364,-0.3393012744587857,-0.7983588379042941,0.3012772815040069,-0.191309831206804,0.2580652147528089,-1.085554403485646,0.3012772815040069,-0.5908507122210328,3.5848660368475693,-0.21250736851480986,0.45307654705381356,0.4096172898409424,-0.04241010240522003,0.6714184729428473,0.8032512025014997,0.4096172898409424,1.2247336356763627,-0.38141593935161383,-0.254846688969337,-0.5908507122210328,1.2247336356763627,0.3012772815040069,-0.5073057591164345,-0.06373662902854216,-0.942446145812876,-0.31821572844136564,1.0021471184507622,-1.825072091951856,1.359078200582899,1.7656129496664057,-0.3393012744587857,-0.5282207546911941,1.742891610000047,0.12885737883854684,1.0243308327237213,1.9708151956500113,0.02167903874393584,1.6068977874861423,0.5402049440683143,1.448967877539575,0.5838735785783277,0.7152942406319166,0.34456029993080256,-0.44444629644309747,0.8693977289284917,0.5620305844376072,0.5402049440683143,-0.5908507122210328,0.4748324586170831,-0.23368633339360326,0.19338072765197223,0.9799801607699364,2.9919327835623593,-0.12760615078476442,0.2580652147528089,-0.2759883981888322,-0.23368633339360326,0.17185499556109507,-0.3393012744587857,-0.6948481366740377,-0.44444629644309747,0.23648587072936555,-0.2759883981888322,0.8032512025014997,-0.254846688969337,0.0859317852989234,-0.04241010240522003,-1.5287741606038916,0.3662283341069291,0.02167903874393584
3,430
Atrophy degeneration affecting the brainstem
7
13
2.255543
0.024099
O00429,P20700,Q9UP83,O60313,Q13813,Q5T160,Q96MW5
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
600,77,581,616,119,697,447
600,616,77,1633,1799,1997,119,697,447,2389,1313,581,872
0.7592385640896675,0.7372578479891295,2.3156233598343645,-0.02106529204966477,-0.10633468895957496,-0.23368633339360326,1.9708151956500113,0.6495063733352072,0.9799801607699364,-0.4654184907728244,0.19338072765197223,0.8032512025014997,0.518396688704323
3,430
Protein localization
30
77
2.250211
0.024436
P51659,Q9NS69,O43681,Q10713,O15254,Q9Y512,Q13190,O15228,P12235,P06576,Q8N4H5,P14735,Q99595,Q9NX63,O60830,Q8TB36,P50542,P09601,Q15067,Q13505,Q9Y5J9,P40855,O75431,P08574,Q9HAV7,A8MXV4,Q9Y5L4,O75381,P25705,P21796
Processes and pathways
Reactome Pathways
msigdb_reactome
645,7,766,414,279,819,165,166,406,40,546,796,703,578,56,191,691,71,718,588,84,714,219,223,760,728,114,240,501,249
728,1704,2094,2585,1432,166,279,1546,766,1231,1100,56,240,2431,219,2300,2795,1985,2881,987,3130,2099,40,223,3366,71,901,406,1811,796,249,1107,501,1745,3229,3342,1814,714,879,1442,691,1524,1205,645,3417,1270,414,3382,165,588,718,2754,2711,1967,1684,1249,546,1492,191,1649,703,2981,760,1731,7,578,2466,3089,2546,1122,1590,1543,819,843,1774,84,114
0.6057338953933035,-0.06373662902854216,-0.2971114238181862,-0.5908507122210328,0.10738556209941592,1.7201861433390337,1.269449542990556,0.04307848903912287,0.5838735785783277,0.23648587072936555,0.3229099381780773,2.547409768053795,1.4039905186201218,-0.5073057591164345,1.4714808810674698,-0.4234551139739826,-0.7570132956764223,-0.23368633339360326,-0.8396256696385406,0.4096172898409424,-1.1262605148954412,-0.2971114238181862,2.8041124444238252,1.448967877539575,-1.9616481810876696,2.40815588672373,0.4748324586170831,1.0243308327237213,-0.12760615078476442,0.5620305844376072,1.3815262161857498,0.3229099381780773,0.8914804711800896,-0.08504483643208101,-1.328560462264458,-1.7465394682740971,-0.12760615078476442,0.6276115039211269,0.4966058497171867,0.10738556209941592,0.6495063733352072,0.06449608277835585,0.2580652147528089,0.7152942406319166,-3.455511531066017,0.21492436389411237,1.0243308327237213,-2.097117677858449,1.742891610000047,0.7812363588966038,0.6276115039211269,-0.7155893800863863,-0.6740874247602239,-0.21250736851480986,-0.04241010240522003,0.23648587072936555,0.8252830651235218,0.0859317852989234,1.6068977874861423,-0.02106529204966477,0.6495063733352072,-0.9219218352181526,0.6057338953933035,-0.06373662902854216,4.283733422464173,0.8032512025014997,-0.5073057591164345,-1.0447671183808418,-0.5491166052451673,0.3229099381780773,0.02167903874393584,0.06449608277835585,0.5620305844376072,0.5402049440683143,-0.08504483643208101,2.2233352367607586,2.0165882176348306
3,430
Cation channel activity
7
19
2.248864
0.024521
O75964,P06576,P24539,P25705,P36542,Q93034,P56385
Functions
GO Molecular function
msigdb_gomf
2,40,109,501,281,58,412
793,2,40,3176,822,1465,109,501,281,1791,521,3294,412,3302,1639,913,1419,58,1324
0.5620305844376072,5.167196520160504,2.8041124444238252,-1.2074277428722162,0.5402049440683143,0.0859317852989234,2.0394981091593998,0.8914804711800896,1.269449542990556,-0.10633468895957496,0.8693977289284917,-1.548678875208257,1.0243308327237213,-1.5685621747527327,-0.02106529204966477,0.4748324586170831,0.12885737883854684,2.547409768053795,0.19338072765197223
3,430
Premature birth
17
41
2.244322
0.024812
P54577,Q9NVS9,O43676,P04062,P27635,Q15427,P36507,P02545,P06753,P57740,O75844,P39019,Q9UQE7,O75381,P40855,Q14683,P50542
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
411,69,4,167,825,44,502,46,176,716,322,797,182,240,714,662,691
1775,4,2671,849,3306,240,322,1513,46,167,176,1047,1334,825,1439,502,797,714,3404,691,1847,2274,411,2039,716,2890,1210,662,44,1820,2569,1564,1896,1902,1939,69,1700,1865,2582,182,1702
-0.10633468895957496,4.551842722059264,-0.6533072855099272,0.518396688704323,-1.5884240069937268,1.4039905186201218,1.1800836337709497,0.06449608277835585,2.6872054940154664,1.7201861433390337,1.6748229295823038,0.3662283341069291,0.17185499556109507,0.5402049440683143,0.10738556209941592,0.8914804711800896,0.5620305844376072,0.6276115039211269,-2.867198385893133,0.6495063733352072,-0.14885918591010985,-0.40244498209708657,1.0243308327237213,-0.254846688969337,0.6276115039211269,-0.8396256696385406,0.2580652147528089,0.6933477721843095,2.7105571292304815,-0.12760615078476442,-0.569993271061387,0.04307848903912287,-0.17009375816547115,-0.17009375816547115,-0.191309831206804,2.431327036159296,-0.04241010240522003,-0.14885918591010985,-0.569993271061387,1.6748229295823038,-0.04241010240522003
3,430
Calcium regulation in cardiac cells
11
30
2.222226
0.026268
Q04917,P16615,P62258,P27348,Q9Y3B8,P31946,P61981,P05771,O43665,P0DP25,P63104
Processes and pathways
WikiPathways
msigdb_wp
284,602,67,677,278,178,427,584,54,338,316
54,734,584,1465,1549,338,1236,1074,602,1632,1879,852,1919,677,3293,178,2828,2275,427,67,2307,1373,316,1444,284,1598,2071,2280,2992,278
2.5706715559059043,0.6057338953933035,0.7812363588966038,0.0859317852989234,0.04307848903912287,1.1577834161963467,0.23648587072936555,0.34456029993080256,0.7592385640896675,-0.02106529204966477,-0.17009375816547115,0.518396688704323,-0.191309831206804,0.6714184729428473,-1.548678875208257,1.6748229295823038,-0.7776958844485033,-0.40244498209708657,1.0021471184507622,2.431327036159296,-0.4234551139739826,0.15034720133396523,1.2024003828056788,0.10738556209941592,1.269449542990556,0.0002977667180233936,-0.2759883981888322,-0.40244498209708657,-0.942446145812876,1.291832142745204
3,430
Proteasome accessory complex
8
21
2.217483
0.02659
O43242,O00231,P17980,Q9UNM6,P62191,P61289,P62195,P48556
Localization
GO Cellular component
msigdb_gocc
375,356,454,269,184,213,214,445
356,2699,1777,375,454,1790,798,445,940,2377,213,184,214,2239,1026,772,470,2731,1934,1159,269
1.1132326864910351,-0.6740874247602239,-0.10633468895957496,1.0687484169607406,0.9578299883515244,-0.10633468895957496,0.5620305844376072,0.9799801607699364,0.45307654705381356,-0.4654184907728244,1.4940100655111697,1.65216523300499,1.4940100655111697,-0.38141593935161383,0.387914008197925,0.5838735785783277,0.9356966299859146,-0.6948481366740377,-0.191309831206804,0.3012772815040069,1.314231136956651
3,430
Tube feeding
28
72
2.212915
0.026904
Q15233,P36776,Q14683,P61978,Q9UDR5,Q9UHX1,P54577,P37268,Q9Y448,P06753,Q9UP83,Q14204,P17480,P55011,Q96N66,Q2M389,Q8TD30,P15311,P07602,Q00610,Q14139,Q7L7X3,O00429,O75962,Q01105,P49591,P42704,Q8N3U4
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
128,395,662,535,816,554,411,32,172,176,581,833,453,829,863,471,474,87,212,745,606,755,600,106,624,622,739,383
600,3166,1877,848,2553,1808,106,176,212,1841,87,453,2774,968,1440,1474,395,32,739,622,1443,411,829,535,1339,745,624,3080,1145,1799,1210,1851,606,833,662,128,471,2076,1088,2079,3369,755,2536,383,2001,2287,474,1310,3018,2291,2183,1003,2642,2008,3197,863,2151,1831,1862,1937,2461,1318,2647,1771,2580,816,554,1836,581,2092,172,3121
0.7592385640896675,-1.1871666764907194,-0.17009375816547115,0.518396688704323,-0.569993271061387,-0.12760615078476442,2.0394981091593998,1.6748229295823038,1.4940100655111697,-0.14885918591010985,2.177283285595381,0.9578299883515244,-0.736311113618571,0.43133814681776855,0.10738556209941592,0.0859317852989234,1.0465312750378557,2.9213897370852018,0.6057338953933035,0.7372578479891295,0.10738556209941592,1.0243308327237213,0.5402049440683143,0.8473319171085857,0.17185499556109507,0.6057338953933035,0.7372578479891295,-1.0447671183808418,0.3012772815040069,-0.10633468895957496,0.2580652147528089,-0.14885918591010985,0.7592385640896675,0.5402049440683143,0.6933477721843095,1.9022729265558864,0.9356966299859146,-0.2759883981888322,0.34456029993080256,-0.2759883981888322,-1.9616481810876696,0.6057338953933035,-0.5491166052451673,1.0687484169607406,-0.23368633339360326,-0.40244498209708657,0.9356966299859146,0.19338072765197223,-0.9629504767360699,-0.40244498209708657,-0.3393012744587857,0.4096172898409424,-0.6116888886017858,-0.23368633339360326,-1.24788811226539,0.518396688704323,-0.31821572844136564,-0.12760615078476442,-0.14885918591010985,-0.191309831206804,-0.5073057591164345,0.19338072765197223,-0.6116888886017858,-0.08504483643208101,-0.569993271061387,0.5620305844376072,0.8252830651235218,-0.12760615078476442,0.8032512025014997,-0.2759883981888322,1.6974965747963648,-1.085554403485646
3,430
Intrinsic pathway for apoptosis
9
19
2.211191
0.027023
Q04917,Q9NR28,P62258,Q9Y3B8,P31946,P61981,Q07021,P63104,P42574
Processes and pathways
Reactome Pathways
msigdb_reactome
284,552,67,278,178,427,217,316,533
2302,677,1169,1439,1667,178,2168,533,1882,427,67,316,2991,284,217,995,3190,552,278
-0.4234551139739826,0.6714184729428473,0.2796623627116229,0.10738556209941592,-0.04241010240522003,1.6748229295823038,-0.3393012744587857,0.8473319171085857,-0.17009375816547115,1.0021471184507622,2.431327036159296,1.2024003828056788,-0.942446145812876,1.269449542990556,1.4940100655111697,0.4096172898409424,-1.227668237248389,0.8252830651235218,1.291832142745204
3,430
Steroid binding
10
23
2.208601
0.027202
Q14849,P45880,P04062,P38435,O75477,O15118,Q96SU4,O94905,P21796,O00264
Functions
GO Molecular function
msigdb_gomf
1,603,167,643,357,265,273,582,249,95
95,265,672,357,582,167,1261,1465,249,1918,1107,2592,1747,643,603,3356,2142,1,273,2644,1613,1096,3274
2.108321019317115,1.314231136956651,0.6714184729428473,1.1132326864910351,0.7812363588966038,1.7201861433390337,0.21492436389411237,0.0859317852989234,1.3815262161857498,-0.191309831206804,0.3229099381780773,-0.5908507122210328,-0.08504483643208101,0.7152942406319166,0.7592385640896675,-1.825072091951856,-0.31821572844136564,5.2664158196818995,1.291832142745204,-0.6116888886017858,0.0002977667180233936,0.34456029993080256,-1.4489421856887923
3,430
Electron transport
17
46
2.20731
0.027292
P00403,Q9Y6M9,O43676,P08574,P51970,P22695,Q6DKK2,Q9P0J0,P14927,O75306,Q9UDW1,O43169,Q16718,P03886,O95864,Q86Y39,O00217
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
558,449,4,223,397,232,267,45,14,514,579,115,146,500,688,352,656
656,2858,1367,115,2195,4,3021,2587,514,2369,1435,710,1514,3175,2060,688,1515,558,500,223,2884,14,3142,2332,1334,232,2886,2483,1473,2946,1713,3124,397,1601,146,1180,3030,267,352,1092,1606,953,1903,45,579,449
0.6933477721843095,-0.8190021137923701,0.15034720133396523,1.993693905134758,-0.36036802408587215,4.551842722059264,-0.9834347839005033,-0.5908507122210328,0.8693977289284917,-0.4654184907728244,0.10738556209941592,0.6276115039211269,0.06449608277835585,-1.2074277428722162,-0.2759883981888322,0.6495063733352072,0.06449608277835585,0.8032512025014997,0.8914804711800896,1.448967877539575,-0.8396256696385406,3.537101859755954,-1.1465830158056964,-0.44444629644309747,0.17185499556109507,1.4264710812485106,-0.8396256696385406,-0.5282207546911941,0.0859317852989234,-0.9013775888027895,-0.06373662902854216,-1.1059176287710073,1.0465312750378557,0.0002977667180233936,1.8111031480459492,0.2796623627116229,-0.9834347839005033,1.314231136956651,1.1354997578192654,0.34456029993080256,0.0002977667180233936,0.45307654705381356,-0.17009375816547115,2.7105571292304815,0.8032512025014997,0.9799801607699364
3,430
Anchoring of the basal body to the plasma membrane
13
39
2.200665
0.02776
P06493,P62258,Q9BV73,O15078,O94927,O95613,Q14203,P41208,P61981,Q99996,O75935,Q13561,P07900
Processes and pathways
Reactome Pathways
msigdb_reactome
543,67,309,173,175,515,188,19,427,387,443,415,314
173,821,443,175,515,3005,1132,543,988,314,1632,1879,968,19,1079,2485,2103,1141,427,67,2991,2139,1406,415,1526,188,833,569,1484,696,1216,1822,886,3272,2123,387,309,1863,3246
1.6748229295823038,0.5402049440683143,0.9799801607699364,1.6748229295823038,0.8693977289284917,-0.9629504767360699,0.3012772815040069,0.8252830651235218,0.4096172898409424,1.2024003828056788,-0.02106529204966477,-0.17009375816547115,0.43133814681776855,3.204350628748325,0.34456029993080256,-0.5282207546911941,-0.2971114238181862,0.3012772815040069,1.0021471184507622,2.431327036159296,-0.942446145812876,-0.31821572844136564,0.12885737883854684,1.0243308327237213,0.06449608277835585,1.6068977874861423,0.5402049440683143,0.8032512025014997,0.0859317852989234,0.6495063733352072,0.2580652147528089,-0.12760615078476442,0.4966058497171867,-1.4489421856887923,-0.2971114238181862,1.0687484169607406,1.2247336356763627,-0.14885918591010985,-1.3687716700453372
3,430
AAA+ ATPase domain [IPR003593]
24
57
2.199604
0.027835
O14678,P36776,Q8NCM8,P06576,P43686,P08183,P62191,Q96TA2,Q5T9A4,P46459,Q14204,Q9NUQ8,Q9H078,Q9UN37,P17980,P62195,Q9NVI7,O76031,Q8WVB6,Q9Y4W6,Q8N3C0,P40937,P55072,Q15645
Sequence
InterPro Domain
interpro_domain
763,395,1057,40,798,177,184,187,317,939,833,334,333,980,454,214,354,986,237,895,1000,241,882,650
763,1594,1575,1984,986,40,177,1988,454,1167,1745,1135,2436,2800,1294,1790,395,241,1267,798,939,882,2104,1636,184,214,2239,2173,1112,833,650,317,1054,2756,1000,2001,1492,1057,1251,237,1971,187,2185,2812,1973,333,2390,1732,334,1653,354,1454,980,1869,2965,1590,895
0.5838735785783277,0.0002977667180233936,0.02167903874393584,-0.23368633339360326,0.4096172898409424,2.8041124444238252,1.6748229295823038,-0.23368633339360326,0.9578299883515244,0.2796623627116229,-0.08504483643208101,0.3012772815040069,-0.5073057591164345,-0.7570132956764223,0.19338072765197223,-0.10633468895957496,1.0465312750378557,1.4039905186201218,0.21492436389411237,0.5620305844376072,0.45307654705381356,0.4966058497171867,-0.2971114238181862,-0.02106529204966477,1.65216523300499,1.4940100655111697,-0.38141593935161383,-0.3393012744587857,0.3229099381780773,0.5402049440683143,0.7152942406319166,1.2024003828056788,0.3662283341069291,-0.7155893800863863,0.4096172898409424,-0.23368633339360326,0.0859317852989234,0.3662283341069291,0.23648587072936555,1.4264710812485106,-0.21250736851480986,1.6295235104710366,-0.3393012744587857,-0.7570132956764223,-0.21250736851480986,1.1800836337709497,-0.4654184907728244,-0.06373662902854216,1.1800836337709497,-0.02106529204966477,1.1354997578192654,0.10738556209941592,0.43133814681776855,-0.14885918591010985,-0.9013775888027895,0.02167903874393584,0.4966058497171867
3,430
Abnormal biliary tract morphology
10
26
2.185818
0.028829
P51659,P04062,P09601,O15078,P02545,P36776,Q10713,P07602,P14174,P50542
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
645,167,71,173,46,395,414,212,467,691
173,766,46,167,212,71,467,1369,3220,395,1295,691,645,414,1555,2142,1481,2755,1649,2008,2507,1771,2225,2091,1590,2940
1.6748229295823038,0.5838735785783277,2.6872054940154664,1.7201861433390337,1.4940100655111697,2.40815588672373,0.9356966299859146,0.15034720133396523,-1.3084235436014806,1.0465312750378557,0.19338072765197223,0.6495063733352072,0.7152942406319166,1.0243308327237213,0.04307848903912287,-0.31821572844136564,0.0859317852989234,-0.7155893800863863,-0.02106529204966477,-0.23368633339360326,-0.5282207546911941,-0.08504483643208101,-0.36036802408587215,-0.2759883981888322,0.02167903874393584,-0.8808134501833325
3,430
Intermediate filament based process
6
16
2.184698
0.028911
P58107,P08670,Q16352,P07197,Q15149,Q9UPN3
Processes and pathways
GO Biological process
msigdb_gobp
485,11,82,55,416,321
3166,1289,1103,900,55,11,1957,545,1714,485,2240,416,82,3002,950,321
-1.1871666764907194,0.19338072765197223,0.3229099381780773,0.4748324586170831,2.5706715559059043,3.824533083456319,-0.21250736851480986,0.8252830651235218,-0.06373662902854216,0.9135801145844248,-0.38141593935161383,1.0243308327237213,2.2233352367607586,-0.942446145812876,0.45307654705381356,1.2024003828056788
3,430
Mitochondrial biogenesis
14
35
2.181676
0.029133
O75964,P48047,Q04837,P06576,Q16891,P24539,P00367,Q00059,Q9NX63,P54646,P36542,P25705,O75431,P56385
Processes and pathways
Reactome Pathways
msigdb_reactome
2,521,168,40,360,109,516,50,578,151,281,501,219,412
1366,2625,219,793,2,516,3362,40,109,501,281,1814,521,3168,3320,1748,151,3294,412,50,168,588,2680,360,2755,1999,2637,2289,3018,2389,3129,1316,1319,578,819
0.15034720133396523,-0.6116888886017858,1.4714808810674698,0.5620305844376072,5.167196520160504,0.8693977289284917,-1.8837389062755159,2.8041124444238252,2.0394981091593998,0.8914804711800896,1.269449542990556,-0.12760615078476442,0.8693977289284917,-1.1871666764907194,-1.6478801727558299,-0.08504483643208101,1.7883501373217856,-1.548678875208257,1.0243308327237213,2.64054700619109,1.7201861433390337,0.7812363588966038,-0.6533072855099272,1.1132326864910351,-0.7155893800863863,-0.23368633339360326,-0.6116888886017858,-0.40244498209708657,-0.9629504767360699,-0.4654184907728244,-1.1059176287710073,0.19338072765197223,0.19338072765197223,0.8032512025014997,0.5620305844376072
3,430
Proteasome component (PCI) domain [IPR000717]
11
21
2.179305
0.029309
Q9BT78,P61201,Q14152,O43242,P60228,O00231,Q9UNM6,Q9UBW8,Q7L2H7,Q15008,P48556
Sequence
InterPro Domain
interpro_domain
652,348,257,375,262,356,269,509,243,470,445
356,2699,375,2400,445,262,348,1800,257,470,1685,243,1281,758,652,2017,3311,509,269,1428,894
1.1132326864910351,-0.6740874247602239,1.0687484169607406,-0.4863716580376144,0.9799801607699364,1.3366464985559088,1.1354997578192654,-0.10633468895957496,1.359078200582899,0.9356966299859146,-0.04241010240522003,1.4039905186201218,0.21492436389411237,0.6057338953933035,0.7152942406319166,-0.23368633339360326,-1.5884240069937268,0.8914804711800896,1.314231136956651,0.12885737883854684,0.4966058497171867
3,430
Er to golgi anterograde transport
32
78
2.173738
0.029725
Q5JRA6,Q01082,O15020,Q8WVM8,P24390,Q15363,Q96PC5,Q13561,Q08379,Q8IUR0,Q13190,P48444,P54920,P52907,O14579,Q9UP83,Q8N6H7,P83436,O75935,Q14203,P46459,Q14204,Q96MW5,O60763,O43237,P49257,O43731,Q14789,P47755,O15498,Q13813,Q15436
Processes and pathways
Reactome Pathways
msigdb_reactome
525,256,634,921,13,773,29,415,155,805,165,678,302,301,930,581,835,428,443,188,939,833,447,312,311,562,845,225,991,876,119,649
2128,930,634,2821,876,311,845,312,1128,443,2161,2839,1130,1914,1202,1132,2591,13,1959,939,991,1672,678,562,992,301,2237,2038,2596,302,1141,2444,1718,2991,2139,428,3357,256,155,2174,2491,165,1406,415,119,1581,188,833,225,773,649,2345,525,805,835,2604,921,2002,1310,447,29,1827,1220,2083,2012,1358,2188,2742,2360,1255,2091,581,2055,1508,1703,3291,1067,1591
-0.31821572844136564,0.45307654705381356,0.7152942406319166,-0.7776958844485033,0.4966058497171867,1.2024003828056788,0.518396688704323,1.2024003828056788,0.3012772815040069,0.9799801607699364,-0.3393012744587857,-0.7983588379042941,0.3012772815040069,-0.191309831206804,0.2580652147528089,0.3012772815040069,-0.5908507122210328,3.5848660368475693,-0.21250736851480986,0.45307654705381356,0.4096172898409424,-0.04241010240522003,0.6714184729428473,0.8032512025014997,0.4096172898409424,1.2247336356763627,-0.38141593935161383,-0.254846688969337,-0.5908507122210328,1.2247336356763627,0.3012772815040069,-0.5073057591164345,-0.06373662902854216,-0.942446145812876,-0.31821572844136564,1.0021471184507622,-1.825072091951856,1.359078200582899,1.7656129496664057,-0.3393012744587857,-0.5282207546911941,1.742891610000047,0.12885737883854684,1.0243308327237213,1.9708151956500113,0.02167903874393584,1.6068977874861423,0.5402049440683143,1.448967877539575,0.5838735785783277,0.7152942406319166,-0.44444629644309747,0.8693977289284917,0.5620305844376072,0.5402049440683143,-0.5908507122210328,0.4748324586170831,-0.23368633339360326,0.19338072765197223,0.9799801607699364,2.9919327835623593,-0.12760615078476442,0.2580652147528089,-0.2759883981888322,-0.23368633339360326,0.17185499556109507,-0.3393012744587857,-0.6948481366740377,-0.44444629644309747,0.23648587072936555,-0.2759883981888322,0.8032512025014997,-0.254846688969337,0.0859317852989234,-0.04241010240522003,-1.5287741606038916,0.3662283341069291,0.02167903874393584
3,430
Pigment granule
13
59
2.16995
0.030011
O00560,O75955,P62258,P08238,Q13277,O43852,P31946,P63104,P55209,P35613,P61020,P07900,P04843
Localization
GO Cellular component
msigdb_gocc
154,377,67,404,111,48,178,316,183,26,220,314,378
154,1875,48,1128,377,3314,378,1261,3183,1017,822,314,1465,1916,404,1629,1165,1550,3327,1331,1264,3023,3006,2232,1812,1881,826,178,26,1553,992,1815,3133,1716,2409,2275,183,1961,908,220,67,1718,2445,2200,316,745,111,1343,1177,1028,2243,2143,1248,2661,2048,2956,461,1424,1737
1.7656129496664057,-0.17009375816547115,2.6638687791403814,0.3012772815040069,1.0687484169607406,-1.6280830590258748,1.0687484169607406,0.21492436389411237,-1.227668237248389,0.387914008197925,0.5402049440683143,1.2024003828056788,0.0859317852989234,-0.191309831206804,1.0243308327237213,-0.02106529204966477,0.2796623627116229,0.04307848903912287,-1.66765560705382,0.17185499556109507,0.21492436389411237,-0.9834347839005033,-0.9629504767360699,-0.38141593935161383,-0.12760615078476442,-0.17009375816547115,0.5402049440683143,1.6748229295823038,3.0154764528966274,0.04307848903912287,0.4096172898409424,-0.12760615078476442,-1.1262605148954412,-0.06373662902854216,-0.4863716580376144,-0.40244498209708657,1.65216523300499,-0.21250736851480986,0.4748324586170831,1.4714808810674698,2.431327036159296,-0.06373662902854216,-0.5073057591164345,-0.36036802408587215,1.2024003828056788,0.6057338953933035,2.0165882176348306,0.17185499556109507,0.2796623627116229,0.387914008197925,-0.38141593935161383,-0.31821572844136564,0.23648587072936555,-0.6325077598761806,-0.254846688969337,-0.9013775888027895,0.9578299883515244,0.12885737883854684,-0.06373662902854216
3,430
Mitochondrial membrane organization
20
50
2.158998
0.03085
O95202,Q9NS69,P12235,Q9P0J0,Q9NX63,P07900,P50542,O14737,Q13505,Q9Y5J9,P0DP25,Q15070,O75431,Q9Y5Z4,P45880,Q9UII2,Q8IWA4,Q16891,Q9Y5L4,O60313
Processes and pathways
GO Biological process
msigdb_gobp
638,7,406,45,578,314,691,206,588,84,338,589,219,94,603,363,488,360,114,616
1874,206,616,709,219,987,638,2302,2331,314,1629,338,406,3059,1667,1746,1814,2560,603,1295,3094,691,2948,995,588,589,360,1967,2634,2755,1999,488,2453,2116,2118,3129,3414,7,1319,578,45,363,1590,895,819,843,1774,84,114,94
-0.17009375816547115,1.5165554046538223,0.7372578479891295,0.6276115039211269,1.4714808810674698,0.4096172898409424,0.7152942406319166,-0.4234551139739826,-0.44444629644309747,1.2024003828056788,-0.02106529204966477,1.1577834161963467,1.0243308327237213,-1.024343149410197,-0.04241010240522003,-0.08504483643208101,-0.12760615078476442,-0.569993271061387,0.7592385640896675,0.19338072765197223,-1.0651708848393058,0.6495063733352072,-0.9013775888027895,0.4096172898409424,0.7812363588966038,0.7812363588966038,1.1132326864910351,-0.21250736851480986,-0.6116888886017858,-0.7155893800863863,-0.23368633339360326,0.9135801145844248,-0.5073057591164345,-0.2971114238181862,-0.2971114238181862,-1.1059176287710073,-3.298052234067302,4.283733422464173,0.19338072765197223,0.8032512025014997,2.7105571292304815,1.1132326864910351,0.02167903874393584,0.4966058497171867,0.5620305844376072,0.5402049440683143,-0.08504483643208101,2.2233352367607586,2.0165882176348306,2.131292988821414
3,430
Selective autophagy
11
35
2.157223
0.030988
O43237,Q9NS69,P61088,Q8IWA4,P08670,O95613,Q9UBN7,P68400,P54646,P21796,P07900
Processes and pathways
Reactome Pathways
msigdb_reactome
311,7,455,488,11,515,246,215,151,249,314
311,847,987,515,3130,1132,314,11,1165,936,249,691,1748,151,882,455,2991,1339,2139,215,661,1406,1581,833,2754,488,546,3032,2219,3329,1220,2083,7,246,1067
1.2024003828056788,0.518396688704323,0.4096172898409424,0.8693977289284917,-1.1262605148954412,0.3012772815040069,1.2024003828056788,3.824533083456319,0.2796623627116229,0.45307654705381356,1.3815262161857498,0.6495063733352072,-0.08504483643208101,1.7883501373217856,0.4966058497171867,0.9578299883515244,-0.942446145812876,0.17185499556109507,-0.31821572844136564,1.4940100655111697,0.6933477721843095,0.12885737883854684,0.02167903874393584,0.5402049440683143,-0.7155893800863863,0.9135801145844248,0.8252830651235218,-0.9834347839005033,-0.36036802408587215,-1.66765560705382,0.2580652147528089,-0.2759883981888322,4.283733422464173,1.4039905186201218,0.3662283341069291
3,430
Transporter complex
17
58
2.153408
0.031287
Q9Y6M9,O43676,P08574,P51970,P22695,Q9P0J0,P14927,O75306,Q9Y5L4,Q9C0H2,Q16718,Q9Y5J9,P0DP25,O75381,Q99996,P03886,Q86Y39
Localization
GO Cellular component
msigdb_gocc
449,4,223,397,232,45,14,514,114,150,146,84,338,240,387,500,352
656,2622,2858,763,1367,4,3021,2587,514,2369,240,1435,710,1514,3175,2060,1515,500,1261,223,338,14,1632,1879,3142,232,2886,1473,1713,3124,2274,397,680,2275,1819,3029,146,1180,913,352,1056,1529,3283,1419,1092,1004,387,3419,150,1653,45,579,1590,1774,84,114,2857,449
0.6933477721843095,-0.6116888886017858,-0.8190021137923701,0.5838735785783277,0.15034720133396523,4.551842722059264,-0.9834347839005033,-0.5908507122210328,0.8693977289284917,-0.4654184907728244,1.4039905186201218,0.10738556209941592,0.6276115039211269,0.06449608277835585,-1.2074277428722162,-0.2759883981888322,0.06449608277835585,0.8914804711800896,0.21492436389411237,1.448967877539575,1.1577834161963467,3.537101859755954,-0.02106529204966477,-0.17009375816547115,-1.1465830158056964,1.4264710812485106,-0.8396256696385406,0.0859317852989234,-0.06373662902854216,-1.1059176287710073,-0.40244498209708657,1.0465312750378557,0.6714184729428473,-0.40244498209708657,-0.12760615078476442,-0.9834347839005033,1.8111031480459492,0.2796623627116229,0.4748324586170831,1.1354997578192654,0.3662283341069291,0.06449608277835585,-1.5088480828737614,0.12885737883854684,0.34456029993080256,0.4096172898409424,1.0687484169607406,-3.9956637327190903,1.8111031480459492,-0.02106529204966477,2.7105571292304815,0.8032512025014997,0.02167903874393584,-0.08504483643208101,2.2233352367607586,2.0165882176348306,-0.7983588379042941,0.9799801607699364
3,430
Positive regulation of protein catabolic process
21
74
2.149334
0.031608
O60826,P35241,P51572,Q13190,P04062,Q9P0J0,Q9UK41,P62191,P46934,P07900,P17980,P68400,O75150,P15311,P62195,Q6ZXV5,P26038,Q9UII2,Q96HY6,Q96JB5,Q96QK1
Processes and pathways
GO Biological process
msigdb_gobp
376,25,410,165,167,45,580,184,561,314,454,215,337,87,214,351,90,363,104,372,507
2744,1779,1231,2159,376,337,1128,2401,966,2098,935,167,314,1073,796,87,454,90,25,1790,798,2136,879,939,561,1295,1714,3094,2409,410,2485,623,882,2657,184,214,2239,1884,215,1209,2923,165,565,911,3322,2496,351,3380,1250,2572,2757,2455,104,2008,372,702,507,3280,1095,2934,3216,1835,45,363,3217,580,1361,2697,1734,1009,1505,2230,2512,1363
-0.7155893800863863,-0.10633468895957496,0.23648587072936555,-0.3393012744587857,1.0687484169607406,1.1577834161963467,0.3012772815040069,-0.4863716580376144,0.43133814681776855,-0.2971114238181862,0.45307654705381356,1.7201861433390337,1.2024003828056788,0.34456029993080256,0.5620305844376072,2.177283285595381,0.9578299883515244,2.131292988821414,3.0861951345931513,-0.10633468895957496,0.5620305844376072,-0.31821572844136564,0.4966058497171867,0.45307654705381356,0.8032512025014997,0.19338072765197223,-0.06373662902854216,-1.0651708848393058,-0.4863716580376144,1.0243308327237213,-0.5282207546911941,0.7372578479891295,0.4966058497171867,-0.6325077598761806,1.65216523300499,1.4940100655111697,-0.38141593935161383,-0.17009375816547115,1.4940100655111697,0.2580652147528089,-0.8808134501833325,1.742891610000047,0.8032512025014997,0.4748324586170831,-1.6478801727558299,-0.5282207546911941,1.1354997578192654,-2.077833421634854,0.23648587072936555,-0.569993271061387,-0.7155893800863863,-0.5073057591164345,2.0624235558075372,-0.23368633339360326,1.0909822301776992,0.6495063733352072,0.8914804711800896,-1.4889006936454316,0.34456029993080256,-0.8808134501833325,-1.2882658134684348,-0.12760615078476442,2.7105571292304815,1.1132326864910351,-1.2882658134684348,0.8032512025014997,0.17185499556109507,-0.6533072855099272,-0.06373662902854216,0.4096172898409424,0.0859317852989234,-0.36036802408587215,-0.5282207546911941,0.17185499556109507
3,430
Protein targeting to mitochondrion
11
46
2.140048
0.032351
P51572,Q9UII2,Q9NS69,Q9P0J0,O14737,Q9Y5L4,Q9Y5J9,Q10713,O60830,Q8TB36,P07900
Processes and pathways
GO Biological process
msigdb_gobp
410,363,7,45,206,114,84,414,56,191,314
984,206,2585,1546,56,2300,987,2098,2477,1235,2770,3130,314,901,936,2592,1746,562,3094,410,1111,1405,414,2754,1051,1967,2634,1684,1250,546,191,2577,703,438,1188,760,7,45,2191,363,2986,819,843,1774,84,114
0.4096172898409424,1.5165554046538223,-0.5908507122210328,0.04307848903912287,2.547409768053795,-0.4234551139739826,0.4096172898409424,-0.2971114238181862,-0.5282207546911941,0.23648587072936555,-0.736311113618571,-1.1262605148954412,1.2024003828056788,0.4748324586170831,0.45307654705381356,-0.5908507122210328,-0.08504483643208101,0.8032512025014997,-1.0651708848393058,1.0243308327237213,0.3229099381780773,0.12885737883854684,1.0243308327237213,-0.7155893800863863,0.3662283341069291,-0.21250736851480986,-0.6116888886017858,-0.04241010240522003,0.23648587072936555,0.8252830651235218,1.6068977874861423,-0.569993271061387,0.6495063733352072,1.0021471184507622,0.2796623627116229,0.6057338953933035,4.283733422464173,2.7105571292304815,-0.3393012744587857,1.1132326864910351,-0.9219218352181526,0.5620305844376072,0.5402049440683143,-0.08504483643208101,2.2233352367607586,2.0165882176348306
3,430
Microtubule binding
25
85
2.136803
0.032614
Q9UH99,Q96DB5,P49454,P41208,Q08379,Q9UBK9,Q9Y448,O15078,P07197,Q14203,Q9UPN3,P50570,Q15691,Q14980,P49354,Q9Y496,P15311,Q92974,Q8NBT2,O00429,P33176,Q9Y295,Q9UBN7,O75381,O60313
Functions
GO Molecular function
msigdb_gomf
654,527,396,19,155,553,172,173,55,188,321,194,696,456,203,205,87,92,353,600,110,374,246,240,616
1365,600,173,1574,1230,1659,616,1287,1983,240,2231,2701,2433,1463,2402,55,87,2035,3335,1440,110,2273,19,739,1079,2438,203,396,194,1081,2485,2171,2487,3353,1639,3027,2240,1209,155,1799,1526,188,3065,456,1244,719,696,3203,2713,1822,886,353,3350,92,1585,527,2761,2609,2123,1035,2504,1059,1499,1094,2323,866,2187,2016,2543,1863,2258,2818,2466,1906,553,246,654,1621,1867,2668,321,374,1507,172,205
0.15034720133396523,0.7592385640896675,1.6748229295823038,0.02167903874393584,0.23648587072936555,-0.04241010240522003,0.7372578479891295,0.19338072765197223,-0.23368633339360326,1.4039905186201218,-0.38141593935161383,-0.6740874247602239,-0.5073057591164345,0.0859317852989234,-0.4863716580376144,2.5706715559059043,2.177283285595381,-0.254846688969337,-1.70714122168277,0.10738556209941592,2.0165882176348306,-0.40244498209708657,3.204350628748325,0.6057338953933035,0.34456029993080256,-0.5073057591164345,1.5391168723820783,1.0465312750378557,1.5842880896557086,0.34456029993080256,-0.5282207546911941,-0.3393012744587857,-0.5282207546911941,-1.8054720591354487,-0.02106529204966477,-0.9834347839005033,-0.38141593935161383,0.2580652147528089,1.7656129496664057,-0.10633468895957496,0.06449608277835585,1.6068977874861423,-1.024343149410197,0.9578299883515244,0.23648587072936555,0.6276115039211269,0.6495063733352072,-1.2680873203022425,-0.6740874247602239,-0.12760615078476442,0.4966058497171867,1.1354997578192654,-1.7662056912720292,2.131292988821414,0.02167903874393584,0.8693977289284917,-0.7155893800863863,-0.5908507122210328,-0.2971114238181862,0.387914008197925,-0.5282207546911941,0.3662283341069291,0.0859317852989234,0.34456029993080256,-0.4234551139739826,0.518396688704323,-0.3393012744587857,-0.23368633339360326,-0.5491166052451673,-0.14885918591010985,-0.38141593935161383,-0.7570132956764223,-0.5073057591164345,-0.17009375816547115,0.8252830651235218,1.4039905186201218,0.7152942406319166,0.0002977667180233936,-0.14885918591010985,-0.6325077598761806,1.2024003828056788,1.0909822301776992,0.0859317852989234,1.6974965747963648,1.5391168723820783
3,430
Biliary tract abnormality
11
29
2.133712
0.032866
P51659,O95202,P04062,P09601,O15078,P02545,P36776,Q10713,P07602,P14174,P50542
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
645,638,167,71,173,46,395,414,212,467,691
173,766,638,2919,46,167,212,71,467,1369,3220,395,1295,691,645,414,1555,2241,2142,1481,2755,1649,2008,2507,1771,2225,2091,1590,2940
1.6748229295823038,0.5838735785783277,0.7152942406319166,-0.8808134501833325,2.6872054940154664,1.7201861433390337,1.4940100655111697,2.40815588672373,0.9356966299859146,0.15034720133396523,-1.3084235436014806,1.0465312750378557,0.19338072765197223,0.6495063733352072,0.7152942406319166,1.0243308327237213,0.04307848903912287,-0.38141593935161383,-0.31821572844136564,0.0859317852989234,-0.7155893800863863,-0.02106529204966477,-0.23368633339360326,-0.5282207546911941,-0.08504483643208101,-0.36036802408587215,-0.2759883981888322,0.02167903874393584,-0.8808134501833325
3,430
Translation factors
9
37
2.131429
0.033054
P23588,Q14152,Q15056,O75153,P60228,P29692,O75822,P49770,P24534
Processes and pathways
WikiPathways
msigdb_wp
96,257,329,66,262,75,270,367,299
1458,1950,1392,2551,1043,66,3261,270,1707,1016,618,1516,1470,1133,96,299,1265,75,367,1239,2708,3201,262,2522,1142,413,1299,3080,1114,2112,257,1212,1480,329,1730,2506,2226
0.0859317852989234,-0.21250736851480986,0.12885737883854684,-0.569993271061387,0.3662283341069291,2.431327036159296,-1.4289311687084396,1.291832142745204,-0.06373662902854216,0.387914008197925,0.7372578479891295,0.06449608277835585,0.0859317852989234,0.3012772815040069,2.108321019317115,1.2247336356763627,0.21492436389411237,2.361859163920826,1.0909822301776992,0.23648587072936555,-0.6740874247602239,-1.2680873203022425,1.3366464985559088,-0.5491166052451673,0.3012772815040069,1.0243308327237213,0.19338072765197223,-1.0447671183808418,0.3229099381780773,-0.2971114238181862,1.359078200582899,0.2580652147528089,0.0859317852989234,1.1800836337709497,-0.06373662902854216,-0.5282207546911941,-0.36036802408587215
3,430
Regulation of actin filament bundle assembly
7
29
2.119107
0.034081
P09493,P49593,Q13177,P16949,P42345,Q13136,P35241
Processes and pathways
GO Biological process
msigdb_gobp
3,408,195,8,233,52,25
2623,1102,1983,2477,3210,3,8,3328,2799,25,233,408,2411,2843,744,2200,2991,2201,52,195,430,2177,1822,2418,809,2787,2465,1839,2915
-0.6116888886017858,0.3229099381780773,-0.23368633339360326,-0.5282207546911941,-1.2882658134684348,4.649741438376801,4.186646783930239,-1.66765560705382,-0.7570132956764223,3.0861951345931513,1.4264710812485106,1.0243308327237213,-0.4863716580376144,-0.7983588379042941,0.6057338953933035,-0.36036802408587215,-0.942446145812876,-0.36036802408587215,2.6172401968299104,1.5842880896557086,1.0021471184507622,-0.3393012744587857,-0.12760615078476442,-0.4863716580376144,0.5620305844376072,-0.736311113618571,-0.5073057591164345,-0.12760615078476442,-0.8602294627439812
3,430
Translocation of slc2a4 glut4 to the plasma membrane
12
37
2.112959
0.034604
Q04917,P62258,Q9Y496,Q96A65,Q9Y3B8,P31946,Q9UPT5,P61981,P54646,O60645,P35579,P63104
Processes and pathways
Reactome Pathways
msigdb_reactome
284,67,205,307,278,178,113,427,151,423,444,316
1948,791,844,1911,423,1132,3367,676,677,178,444,3319,1748,151,2103,1579,2105,427,67,2200,316,2139,284,1342,1581,3117,780,307,492,1220,2083,3228,1772,113,278,205,1737
-0.21250736851480986,0.5620305844376072,0.518396688704323,-0.191309831206804,1.0021471184507622,0.3012772815040069,-1.9616481810876696,0.6714184729428473,0.6714184729428473,1.6748229295823038,0.9799801607699364,-1.6478801727558299,-0.08504483643208101,1.7883501373217856,-0.2971114238181862,0.02167903874393584,-0.2971114238181862,1.0021471184507622,2.431327036159296,-0.36036802408587215,1.2024003828056788,-0.31821572844136564,1.269449542990556,0.17185499556109507,0.02167903874393584,-1.085554403485646,0.5838735785783277,1.2247336356763627,0.9135801145844248,0.2580652147528089,-0.2759883981888322,-1.3084235436014806,-0.08504483643208101,2.0165882176348306,1.291832142745204,1.5391168723820783,-0.06373662902854216
3,430
Proteasome regulatory particle
7
18
2.111746
0.034708
O43242,O00231,P17980,Q9UNM6,P62191,P62195,P48556
Localization
GO Cellular component
msigdb_gocc
375,356,454,269,184,214,445
356,2699,1777,375,454,1790,798,445,940,2377,184,214,2239,772,470,2731,1934,269
1.1132326864910351,-0.6740874247602239,-0.10633468895957496,1.0687484169607406,0.9578299883515244,-0.10633468895957496,0.5620305844376072,0.9799801607699364,0.45307654705381356,-0.4654184907728244,1.65216523300499,1.4940100655111697,-0.38141593935161383,0.5838735785783277,0.9356966299859146,-0.6948481366740377,-0.191309831206804,1.314231136956651
3,430
Mitotic prometaphase
34
102
2.111623
0.034719
P30154,P49454,O95613,P41208,Q14683,Q13561,P14635,P06493,O14777,Q9BV73,O15078,O94927,O43683,Q96EA4,Q9NTJ3,P61981,Q9UQE7,O75935,Q14203,P07900,O43237,Q15691,P62258,Q9BZD4,Q14980,P57740,P68400,Q16537,Q8NBT2,Q9Y266,O95347,Q8N3U4,Q99996,O95067
Processes and pathways
Reactome Pathways
msigdb_reactome
517,396,515,19,662,415,658,543,162,309,173,175,673,574,440,427,182,443,188,314,311,696,67,596,456,716,215,339,353,633,366,383,387,499
1365,162,1228,173,311,1980,673,2794,821,2671,2026,1983,443,175,499,366,515,3005,1132,543,988,314,658,1632,1879,936,968,517,1440,3230,19,1079,2170,396,1844,2376,2485,716,1141,427,67,2991,1339,2139,215,1677,1406,415,1581,1526,188,833,662,1344,456,2342,1643,1483,1484,696,339,1346,1448,3098,1216,1893,1491,755,1822,886,3373,383,353,3244,3046,1896,920,2810,1585,574,1150,2123,2504,387,1424,1499,1220,309,2083,1383,596,1863,2258,2463,2391,440,1906,3246,182,633,1285,1067
0.15034720133396523,1.742891610000047,0.23648587072936555,1.6748229295823038,1.2024003828056788,-0.23368633339360326,0.6714184729428473,-0.7570132956764223,0.5402049440683143,-0.6533072855099272,-0.254846688969337,-0.23368633339360326,0.9799801607699364,1.6748229295823038,0.8914804711800896,1.0909822301776992,0.8693977289284917,-0.9629504767360699,0.3012772815040069,0.8252830651235218,0.4096172898409424,1.2024003828056788,0.6933477721843095,-0.02106529204966477,-0.17009375816547115,0.45307654705381356,0.43133814681776855,0.8693977289284917,0.10738556209941592,-1.328560462264458,3.204350628748325,0.34456029993080256,-0.3393012744587857,1.0465312750378557,-0.14885918591010985,-0.4654184907728244,-0.5282207546911941,0.6276115039211269,0.3012772815040069,1.0021471184507622,2.431327036159296,-0.942446145812876,0.17185499556109507,-0.31821572844136564,1.4940100655111697,-0.04241010240522003,0.12885737883854684,1.0243308327237213,0.02167903874393584,0.06449608277835585,1.6068977874861423,0.5402049440683143,0.6933477721843095,0.17185499556109507,0.9578299883515244,-0.44444629644309747,-0.02106529204966477,0.0859317852989234,0.0859317852989234,0.6495063733352072,1.1577834161963467,0.17185499556109507,0.10738556209941592,-1.0651708848393058,0.2580652147528089,-0.17009375816547115,0.0859317852989234,0.6057338953933035,-0.12760615078476442,0.4966058497171867,-1.9810691920969703,1.0687484169607406,1.1354997578192654,-1.3687716700453372,-1.0038990229805613,-0.17009375816547115,0.4748324586170831,-0.7570132956764223,0.02167903874393584,0.8032512025014997,0.3012772815040069,-0.2971114238181862,-0.5282207546911941,1.0687484169607406,0.12885737883854684,0.0859317852989234,0.2580652147528089,1.2247336356763627,-0.2759883981888322,0.15034720133396523,0.7812363588966038,-0.14885918591010985,-0.38141593935161383,-0.5073057591164345,-0.4654184907728244,1.0021471184507622,-0.17009375816547115,-1.3687716700453372,1.6748229295823038,0.7372578479891295,0.21492436389411237,0.3662283341069291
3,430
Chromosome organization involved in meiotic cell cycle
10
18
2.111519
0.034728
Q92791,Q92878,O43683,Q9NTJ3,P42695,O95347,Q13315,O94901,Q15645,P46379
Processes and pathways
GO Biological process
msigdb_gobp
460,268,673,440,585,366,661,933,650,879
673,2671,2026,933,366,968,585,879,1673,661,2342,1483,650,460,268,1651,1829,440
0.6714184729428473,-0.6533072855099272,-0.254846688969337,0.45307654705381356,1.0909822301776992,0.43133814681776855,0.7812363588966038,0.4966058497171867,-0.04241010240522003,0.6933477721843095,-0.44444629644309747,0.0859317852989234,0.7152942406319166,0.9578299883515244,1.314231136956651,-0.02106529204966477,-0.12760615078476442,1.0021471184507622
3,430
Mitochondrial calcium ion transport
6
15
2.095067
0.036165
P45880,Q10713,Q9UJZ1,Q99623,Q96TA2,P21796
Processes and pathways
Reactome Pathways
msigdb_reactome
603,414,390,89,187,249
2300,638,249,1400,603,414,1529,1419,2118,2318,187,89,390,2549,895
-0.4234551139739826,0.7152942406319166,1.3815262161857498,0.12885737883854684,0.7592385640896675,1.0243308327237213,0.06449608277835585,0.12885737883854684,-0.2971114238181862,-0.4234551139739826,1.6295235104710366,2.177283285595381,1.0687484169607406,-0.5491166052451673,0.4966058497171867
3,430
Cytokine receptor binding
11
24
2.094716
0.036196
P54577,O00560,Q8WUH2,P48681,Q8WXW3,Q9Y5K6,Q9Y4E8,Q9UNH7,P14174,Q12931,P42574
Functions
GO Molecular function
msigdb_gomf
411,154,683,545,371,247,671,186,467,694,533
154,1623,467,2061,903,2063,533,545,411,1082,694,2175,1176,1967,683,371,809,2008,3088,1284,1065,186,671,247
1.7656129496664057,-0.02106529204966477,0.9356966299859146,-0.2759883981888322,0.4748324586170831,-0.2759883981888322,0.8473319171085857,0.8252830651235218,1.0243308327237213,0.34456029993080256,0.6495063733352072,-0.3393012744587857,0.2796623627116229,-0.21250736851480986,0.6714184729428473,1.0909822301776992,0.5620305844376072,-0.23368633339360326,-1.0447671183808418,0.21492436389411237,0.3662283341069291,1.65216523300499,0.6933477721843095,1.4039905186201218
3,430
protein modifying enzyme
12
26
2.093176
0.036333
Q6NYC1,O14744,Q92791,Q8NBJ5,P50897,O60568,O75718,O15460,O60476,Q6P2P2,O60725,Q9Y570
Functions
Panther Protein class
panther_protein_class
723,346,460,400,139,141,732,391,51,473,86,614
1741,346,1979,391,51,141,1512,86,732,1105,139,3062,1719,831,2709,1178,3296,723,473,2637,2350,400,460,1586,1314,614
-0.08504483643208101,1.1354997578192654,-0.23368633339360326,1.0465312750378557,2.6172401968299104,1.8338719570141517,0.06449608277835585,2.177283285595381,0.6057338953933035,0.3229099381780773,1.8566565394965713,-1.024343149410197,-0.06373662902854216,0.5402049440683143,-0.6740874247602239,0.2796623627116229,-1.548678875208257,0.6276115039211269,0.9356966299859146,-0.6116888886017858,-0.44444629644309747,1.0465312750378557,0.9578299883515244,0.02167903874393584,0.19338072765197223,0.7592385640896675
3,430
Oxidative phosphorylation
11
30
2.092898
0.036358
Q9Y6M9,O75964,P48047,P51970,P06576,P24539,Q16718,P25705,P03886,Q86Y39,P56385
Processes and pathways
WikiPathways
msigdb_wp
449,2,521,397,40,109,146,501,500,352,412
656,2858,3021,2587,514,2369,1435,710,793,2,1514,3175,2060,1515,500,40,3142,109,501,2886,521,3124,397,3294,412,2730,146,1180,352,449
0.6933477721843095,-0.8190021137923701,-0.9834347839005033,-0.5908507122210328,0.8693977289284917,-0.4654184907728244,0.10738556209941592,0.6276115039211269,0.5620305844376072,5.167196520160504,0.06449608277835585,-1.2074277428722162,-0.2759883981888322,0.06449608277835585,0.8914804711800896,2.8041124444238252,-1.1465830158056964,2.0394981091593998,0.8914804711800896,-0.8396256696385406,0.8693977289284917,-1.1059176287710073,1.0465312750378557,-1.548678875208257,1.0243308327237213,-0.6948481366740377,1.8111031480459492,0.2796623627116229,1.1354997578192654,0.9799801607699364
3,430
Autophagy
17
53
2.089583
0.036655
O43237,Q8WUX9,P08238,Q9NS69,Q8N4H5,P61088,Q8IWA4,P08670,P42345,Q14457,O95613,Q9UBN7,P68400,Q15382,P54646,P21796,P07900
Processes and pathways
Reactome Pathways
msigdb_reactome
311,537,404,7,546,455,488,11,233,358,515,246,215,506,151,249,314
311,847,987,966,515,3130,1132,314,404,11,1165,3240,936,249,233,691,1748,151,882,2171,455,2991,1339,2139,215,661,1406,1581,833,358,506,2754,1489,2501,488,546,537,3032,2219,3329,1826,2643,1220,2083,2693,7,2259,246,580,2057,2229,2968,1067
1.2024003828056788,0.518396688704323,0.4096172898409424,0.43133814681776855,0.8693977289284917,-1.1262605148954412,0.3012772815040069,1.2024003828056788,1.0243308327237213,3.824533083456319,0.2796623627116229,-1.3687716700453372,0.45307654705381356,1.3815262161857498,1.4264710812485106,0.6495063733352072,-0.08504483643208101,1.7883501373217856,0.4966058497171867,-0.3393012744587857,0.9578299883515244,-0.942446145812876,0.17185499556109507,-0.31821572844136564,1.4940100655111697,0.6933477721843095,0.12885737883854684,0.02167903874393584,0.5402049440683143,1.1132326864910351,0.8914804711800896,-0.7155893800863863,0.0859317852989234,-0.5282207546911941,0.9135801145844248,0.8252830651235218,0.8473319171085857,-0.9834347839005033,-0.36036802408587215,-1.66765560705382,-0.12760615078476442,-0.6116888886017858,0.2580652147528089,-0.2759883981888322,-0.6533072855099272,4.283733422464173,-0.38141593935161383,1.4039905186201218,0.8032512025014997,-0.254846688969337,-0.36036802408587215,-0.9013775888027895,0.3662283341069291
3,430
High mobility group box domain [IPR009071]
6
11
2.088921
0.036715
P17480,Q00059,Q9NP66,Q969G3,O15347,P09429
Sequence
InterPro Domain
interpro_domain
453,50,83,120,497,465
497,2823,2919,465,453,621,50,2202,1856,120,83
0.8914804711800896,-0.7776958844485033,-0.8808134501833325,0.9356966299859146,0.9578299883515244,0.7372578479891295,2.64054700619109,-0.36036802408587215,-0.14885918591010985,1.9708151956500113,2.2233352367607586
3,430
High mobility group box domain superfamily [IPR036910]
6
11
2.088921
0.036715
P17480,Q00059,Q9NP66,Q969G3,O15347,P09429
Sequence
InterPro Superfamily
interpro_homologous_superfamily
453,50,83,120,497,465
497,2823,2919,465,453,621,50,2202,1856,120,83
0.8914804711800896,-0.7776958844485033,-0.8808134501833325,0.9356966299859146,0.9578299883515244,0.7372578479891295,2.64054700619109,-0.36036802408587215,-0.14885918591010985,1.9708151956500113,2.2233352367607586
3,430
Substantia nigra development
10
17
2.085463
0.037027
Q04917,P62258,P27348,P12277,P14854,P24539,P00367,O75489,Q16352,P0DP25
Processes and pathways
GO Biological process
msigdb_gobp
284,67,677,138,484,109,516,710,82,338
2821,710,516,1629,338,3178,138,484,109,677,2843,744,67,2991,284,82,2572
-0.7776958844485033,0.6276115039211269,0.8693977289284917,-0.02106529204966477,1.1577834161963467,-1.2074277428722162,1.8566565394965713,0.9135801145844248,2.0394981091593998,0.6714184729428473,-0.7983588379042941,0.6057338953933035,2.431327036159296,-0.942446145812876,1.269449542990556,2.2233352367607586,-0.569993271061387
3,430
Retrognathia
28
82
2.082763
0.037273
Q5JRA6,P51659,O95613,Q5SRE5,Q7LGA3,Q14683,Q96MF7,P37268,Q9UHX1,P54577,Q96PZ0,P04062,Q15427,P02545,P48444,Q9Y2W2,Q9UP83,P83436,Q16625,O75844,P53701,P78318,Q9UL01,Q15392,P82650,Q2TAA5,Q9UPT5,Q96DF8
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
525,645,515,664,144,662,28,32,554,411,549,167,44,46,678,442,581,428,721,322,586,216,613,750,349,751,113,385
2699,1390,1125,931,932,2194,1623,2196,322,2161,966,2371,515,46,167,1917,1438,1370,990,825,2406,2705,32,1791,2167,797,2656,678,645,2594,586,1443,411,216,3064,349,428,2709,2241,3338,2727,1851,662,1853,1272,750,44,3082,2496,721,751,2344,1602,525,664,2712,3346,1722,144,3196,781,1604,2001,3018,385,28,549,1610,2762,1728,2185,1189,1652,2225,554,613,581,113,442,1457,3121,962
-0.6740874247602239,0.12885737883854684,0.3012772815040069,0.45307654705381356,0.45307654705381356,-0.36036802408587215,-0.02106529204966477,-0.36036802408587215,1.1800836337709497,-0.3393012744587857,0.43133814681776855,-0.4654184907728244,0.8693977289284917,2.6872054940154664,1.7201861433390337,-0.191309831206804,0.10738556209941592,0.15034720133396523,0.4096172898409424,0.5402049440683143,-0.4863716580376144,-0.6740874247602239,2.9213897370852018,-0.10633468895957496,-0.3393012744587857,0.5620305844376072,-0.6325077598761806,0.6714184729428473,0.7152942406319166,-0.5908507122210328,0.7812363588966038,0.10738556209941592,1.0243308327237213,1.4940100655111697,-1.024343149410197,1.1354997578192654,1.0021471184507622,-0.6740874247602239,-0.38141593935161383,-1.7268512933556746,-0.6948481366740377,-0.14885918591010985,0.6933477721843095,-0.14885918591010985,0.21492436389411237,0.6057338953933035,2.7105571292304815,-1.0447671183808418,-0.5282207546911941,0.6276115039211269,0.6057338953933035,-0.44444629644309747,0.0002977667180233936,0.8693977289284917,0.6933477721843095,-0.6740874247602239,-1.7465394682740971,-0.06373662902854216,1.8338719570141517,-1.24788811226539,0.5838735785783277,0.0002977667180233936,-0.23368633339360326,-0.9629504767360699,1.0687484169607406,2.9919327835623593,0.8252830651235218,0.0002977667180233936,-0.7155893800863863,-0.06373662902854216,-0.3393012744587857,0.2796623627116229,-0.02106529204966477,-0.36036802408587215,0.8252830651235218,0.7592385640896675,0.8032512025014997,2.0165882176348306,1.0021471184507622,0.10738556209941592,-1.085554403485646,0.45307654705381356
3,430
Sodium ion transmembrane transport
10
21
2.081924
0.037349
Q04917,P50570,O43707,P55011,Q6P4Q7,Q9Y6M7,Q96PU5,P46939,Q14BN4,P46934
Processes and pathways
GO Biological process
msigdb_gobp
284,194,289,829,399,896,702,425,85,561
289,1261,1916,1919,561,425,194,2275,829,284,2491,2280,85,913,399,1219,702,1222,2325,1621,896
1.2470833648713042,0.21492436389411237,-0.191309831206804,-0.191309831206804,0.8032512025014997,1.0021471184507622,1.5842880896557086,-0.40244498209708657,0.5402049440683143,1.269449542990556,-0.5282207546911941,-0.40244498209708657,2.200301566033099,0.4748324586170831,1.0465312750378557,0.2580652147528089,0.6495063733352072,0.2580652147528089,-0.4234551139739826,0.0002977667180233936,0.4966058497171867
3,430
Rho gtpases activate pkns
11
22
2.077853
0.037723
Q04917,P35580,P62258,P27348,P61586,Q9Y3B8,P31946,P61981,Q7Z406,P63104,P35579
Processes and pathways
Reactome Pathways
msigdb_reactome
284,255,67,677,744,278,178,427,117,316,444
1069,1910,1989,677,3213,178,444,255,743,744,427,3042,67,2677,2200,316,2631,284,2177,1447,117,278
0.34456029993080256,-0.191309831206804,-0.23368633339360326,0.6714184729428473,-1.2882658134684348,1.6748229295823038,0.9799801607699364,1.359078200582899,0.6057338953933035,0.6057338953933035,1.0021471184507622,-1.0038990229805613,2.431327036159296,-0.6533072855099272,-0.36036802408587215,1.2024003828056788,-0.6116888886017858,1.269449542990556,-0.3393012744587857,0.10738556209941592,1.993693905134758,1.291832142745204
3,430
Horizontal nystagmus
9
25
2.07127
0.038334
Q9H061,P04062,O15020,O00429,P20700,O94905,O60313,P07602,P52815
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
39,167,634,600,77,582,616,212,91
1874,600,1875,634,616,582,2770,167,212,77,3247,691,91,941,2442,1892,975,2007,39,2464,2508,1617,1771,1734,1198
-0.17009375816547115,0.7592385640896675,-0.17009375816547115,0.7152942406319166,0.7372578479891295,0.7812363588966038,-0.736311113618571,1.7201861433390337,1.4940100655111697,2.3156233598343645,-1.3888458608945973,0.6495063733352072,2.131292988821414,0.45307654705381356,-0.5073057591164345,-0.17009375816547115,0.43133814681776855,-0.23368633339360326,2.8275383601959625,-0.5073057591164345,-0.5282207546911941,0.0002977667180233936,-0.08504483643208101,-0.06373662902854216,0.2796623627116229
3,430
Bruising susceptibility
11
32
2.06579
0.038848
P49257,P04062,P38435,Q14980,O60568,Q13126,Q96L58,Q9NWM8,Q9UL01,Q15149,P35579
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
562,167,643,456,141,327,244,421,613,416,444
984,635,141,167,2557,1236,1632,1879,3328,1439,2705,444,643,2168,1920,562,1553,2274,2890,831,1598,1676,327,2142,456,416,1688,244,1829,421,613,1198
0.4096172898409424,0.7152942406319166,1.8338719570141517,1.7201861433390337,-0.569993271061387,0.23648587072936555,-0.02106529204966477,-0.17009375816547115,-1.66765560705382,0.10738556209941592,-0.6740874247602239,0.9799801607699364,0.7152942406319166,-0.3393012744587857,-0.191309831206804,0.8032512025014997,0.04307848903912287,-0.40244498209708657,-0.8396256696385406,0.5402049440683143,0.0002977667180233936,-0.04241010240522003,1.1800836337709497,-0.31821572844136564,0.9578299883515244,1.0243308327237213,-0.04241010240522003,1.4039905186201218,-0.12760615078476442,1.0243308327237213,0.7592385640896675,0.2796623627116229
3,430
Abnormality of the 1st metacarpal
6
11
2.063704
0.039046
Q15233,O75962,O95613,Q9NVI1,Q9UQE7,Q14683
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
128,106,515,869,182,662
2671,1461,849,106,515,662,128,1820,1829,869,182
-0.6533072855099272,0.0859317852989234,0.518396688704323,2.0394981091593998,0.8693977289284917,0.6933477721843095,1.9022729265558864,-0.12760615078476442,-0.12760615078476442,0.518396688704323,1.6748229295823038
3,430
Regulated exocytosis
12
34
2.061586
0.039247
P16615,Q15907,P09601,Q68EM7,Q99584,Q13277,P54920,P05771,P0DP25,Q9BRK5,Q9UNH7,P35579
Processes and pathways
GO Biological process
msigdb_gobp
602,159,71,330,42,111,302,584,338,23,186,444
791,1126,636,1164,3092,734,584,71,338,1047,3327,1020,602,2945,2799,444,992,1922,302,3009,1579,1639,1209,111,2679,1345,159,2344,330,42,23,2393,2615,186
0.5620305844376072,0.3012772815040069,0.7152942406319166,0.2796623627116229,-1.0651708848393058,0.6057338953933035,0.7812363588966038,2.40815588672373,1.1577834161963467,0.3662283341069291,-1.66765560705382,0.387914008197925,0.7592385640896675,-0.9013775888027895,-0.7570132956764223,0.9799801607699364,0.4096172898409424,-0.191309831206804,1.2247336356763627,-0.9629504767360699,0.02167903874393584,-0.02106529204966477,0.2580652147528089,2.0165882176348306,-0.6533072855099272,0.17185499556109507,1.7656129496664057,-0.44444629644309747,1.1800836337709497,2.8041124444238252,3.109797184993122,-0.4654184907728244,-0.5908507122210328,1.65216523300499
3,430
Nonalcoholic fatty liver disease
18
55
2.061449
0.03926
P14406,P00403,Q9Y6M9,Q86Y39,O43676,P08574,P51970,P22695,P13073,P14854,Q9P0J0,P14927,O75306,Q9UDW1,Q16718,P54646,P20674,P42574
Processes and pathways
WikiPathways
msigdb_wp
560,558,449,352,4,223,397,232,108,484,45,14,514,579,146,151,659,533
656,2193,2858,2942,1367,4,3021,2587,514,2369,1435,710,1514,3175,2060,1515,558,1707,223,1663,1664,108,560,484,14,3211,3142,659,2332,232,2886,2483,1473,533,1713,1553,3124,3094,397,1748,151,1882,2843,2200,3113,995,2175,146,1180,352,2740,2008,45,579,449
0.6933477721843095,-0.36036802408587215,-0.8190021137923701,-0.9013775888027895,0.15034720133396523,4.551842722059264,-0.9834347839005033,-0.5908507122210328,0.8693977289284917,-0.4654184907728244,0.10738556209941592,0.6276115039211269,0.06449608277835585,-1.2074277428722162,-0.2759883981888322,0.06449608277835585,0.8032512025014997,-0.06373662902854216,1.448967877539575,-0.04241010240522003,-0.04241010240522003,2.0394981091593998,0.8032512025014997,0.9135801145844248,3.537101859755954,-1.2882658134684348,-1.1465830158056964,0.6933477721843095,-0.44444629644309747,1.4264710812485106,-0.8396256696385406,-0.5282207546911941,0.0859317852989234,0.8473319171085857,-0.06373662902854216,0.04307848903912287,-1.1059176287710073,-1.0651708848393058,1.0465312750378557,-0.08504483643208101,1.7883501373217856,-0.17009375816547115,-0.7983588379042941,-0.36036802408587215,-1.085554403485646,0.4096172898409424,-0.3393012744587857,1.8111031480459492,0.2796623627116229,1.1354997578192654,-0.6948481366740377,-0.23368633339360326,2.7105571292304815,0.8032512025014997,0.9799801607699364
3,430
Complex i biogenesis
12
30
2.059249
0.03947
Q9BQ95,Q9Y6M9,Q8N183,O43676,P51970,Q9P0J0,O75306,Q9NPL8,Q16718,P03886,Q86Y39,O00217
Processes and pathways
Reactome Pathways
msigdb_reactome
687,449,68,4,397,45,514,476,146,500,352,656
656,4,3021,2587,514,2369,1435,710,1514,3175,2060,1515,500,3142,2886,3124,397,146,1180,1821,352,68,1058,687,3101,1191,476,813,45,449
0.6933477721843095,4.551842722059264,-0.9834347839005033,-0.5908507122210328,0.8693977289284917,-0.4654184907728244,0.10738556209941592,0.6276115039211269,0.06449608277835585,-1.2074277428722162,-0.2759883981888322,0.06449608277835585,0.8914804711800896,-1.1465830158056964,-0.8396256696385406,-1.1059176287710073,1.0465312750378557,1.8111031480459492,0.2796623627116229,-0.12760615078476442,1.1354997578192654,2.431327036159296,0.3662283341069291,0.6714184729428473,-1.0651708848393058,0.2796623627116229,0.9356966299859146,0.5620305844376072,2.7105571292304815,0.9799801607699364
3,430
Regulation of cellular protein catabolic process
25
90
2.05881
0.039512
O60826,P35241,O00560,P51572,P08238,P04062,P62191,P07900,O94874,P17980,P68400,O75150,P15311,P61289,Q6ZXV5,P62195,P26038,P54727,Q04323,Q9UII2,Q96HY6,P62081,Q96JB5,Q96QK1,Q92922
Processes and pathways
GO Biological process
msigdb_gobp
376,25,154,410,404,167,184,314,200,454,215,337,87,213,351,214,90,347,224,363,104,486,372,507,124
2621,1777,154,1779,1228,1979,1392,1231,376,337,2401,200,2330,2098,935,167,822,314,404,1073,87,1632,1879,454,936,824,90,25,1790,798,2136,879,2656,1295,1714,3094,410,2485,2333,623,347,882,2171,1206,213,2657,486,184,214,2239,2106,2802,1884,215,3353,224,1243,1026,1209,2923,3322,351,3380,2572,1563,2757,538,124,808,2049,104,372,2958,507,3329,1095,3088,3191,3216,1835,363,762,1159,2697,1734,1009,1505,2230,2512,1838
-0.6116888886017858,-0.10633468895957496,1.7656129496664057,-0.10633468895957496,0.23648587072936555,-0.23368633339360326,0.12885737883854684,0.23648587072936555,1.0687484169607406,1.1577834161963467,-0.4863716580376144,1.5616944426854624,-0.44444629644309747,-0.2971114238181862,0.45307654705381356,1.7201861433390337,0.5402049440683143,1.2024003828056788,1.0243308327237213,0.34456029993080256,2.177283285595381,-0.02106529204966477,-0.17009375816547115,0.9578299883515244,0.45307654705381356,0.5402049440683143,2.131292988821414,3.0861951345931513,-0.10633468895957496,0.5620305844376072,-0.31821572844136564,0.4966058497171867,-0.6325077598761806,0.19338072765197223,-0.06373662902854216,-1.0651708848393058,1.0243308327237213,-0.5282207546911941,-0.44444629644309747,0.7372578479891295,1.1354997578192654,0.4966058497171867,-0.3393012744587857,0.2580652147528089,1.4940100655111697,-0.6325077598761806,0.9135801145844248,1.65216523300499,1.4940100655111697,-0.38141593935161383,-0.2971114238181862,-0.7570132956764223,-0.17009375816547115,1.4940100655111697,-1.8054720591354487,1.448967877539575,0.23648587072936555,0.387914008197925,0.2580652147528089,-0.8808134501833325,-1.6478801727558299,1.1354997578192654,-2.077833421634854,-0.569993271061387,0.04307848903912287,-0.7155893800863863,0.8473319171085857,1.9479521132618594,0.5620305844376072,-0.254846688969337,2.0624235558075372,1.0909822301776992,-0.9013775888027895,0.8914804711800896,-1.66765560705382,0.34456029993080256,-1.0447671183808418,-1.227668237248389,-1.2882658134684348,-0.12760615078476442,1.1132326864910351,0.6057338953933035,0.3012772815040069,-0.6533072855099272,-0.06373662902854216,0.4096172898409424,0.0859317852989234,-0.36036802408587215,-0.5282207546911941,-0.12760615078476442
3,430
EF-Hand 1, calcium-binding site [IPR018247]
14
41
2.047858
0.040574
Q15293,P14314,Q9H223,O43707,Q14257,O43852,Q9H4M9,P41208,Q9NWM8,Q9BRK5,P0DP25,Q13813,Q9UPN3,P80303
Sequence
InterPro Binding site
interpro_binding_site
457,164,73,289,236,48,344,19,421,23,338,119,321,62
289,48,1462,1985,638,3398,1987,1955,338,466,3399,164,2655,2061,3301,1371,19,2630,2841,62,2832,2240,119,236,1445,457,1722,2453,2116,1930,2688,1311,23,73,344,421,1121,632,3406,321,789
1.2470833648713042,2.6638687791403814,0.0859317852989234,-0.23368633339360326,0.7152942406319166,-2.534175143153114,-0.23368633339360326,-0.21250736851480986,1.1577834161963467,0.9356966299859146,-2.5528891708295545,1.742891610000047,-0.6325077598761806,-0.2759883981888322,-1.5685621747527327,0.15034720133396523,3.204350628748325,-0.6116888886017858,-0.7983588379042941,2.4545133476558236,-0.7776958844485033,-0.38141593935161383,1.9708151956500113,1.4264710812485106,0.10738556209941592,0.9578299883515244,-0.06373662902854216,-0.5073057591164345,-0.2971114238181862,-0.191309831206804,-0.6533072855099272,0.19338072765197223,3.109797184993122,2.40815588672373,1.1577834161963467,1.0243308327237213,0.3229099381780773,0.7372578479891295,-3.012537226216726,1.2024003828056788,0.5838735785783277
3,430
Anticodon-binding domain superfamily [IPR036621]
6
8
2.045888
0.040767
P07814,Q9BW92,Q9HCD5,A2RTX5,P41250,P49590
Sequence
InterPro Superfamily
interpro_homologous_superfamily
823,362,925,707,969,534
707,823,990,969,534,1450,362,925
0.6276115039211269,0.5402049440683143,0.4096172898409424,0.43133814681776855,0.8473319171085857,0.10738556209941592,1.1132326864910351,0.4748324586170831
3,430
Nucleoside triphosphate metabolic process
13
47
2.045566
0.040799
O75964,Q8IWA4,P06576,P55263,Q9H773,Q05682,Q96DE0,P24539,Q9UJZ1,P36542,P25705,P04818,P56385
Processes and pathways
GO Biological process
msigdb_gobp
2,488,40,10,74,204,308,109,390,281,501,60,412
2266,616,1985,793,2,558,3153,3141,60,40,3055,1549,1262,2826,3313,1468,1134,109,501,1203,1666,1399,3235,281,1791,521,882,10,3294,412,744,2445,204,1801,2500,488,2866,308,3278,1830,74,1225,2546,390,2650,1326,1285
-0.40244498209708657,0.7372578479891295,-0.23368633339360326,0.5620305844376072,5.167196520160504,0.8032512025014997,-1.1668850851929853,-1.1465830158056964,2.500931367431874,2.8041124444238252,-1.024343149410197,0.04307848903912287,0.21492436389411237,-0.7776958844485033,-1.6082643193752386,0.0859317852989234,0.3012772815040069,2.0394981091593998,0.8914804711800896,0.2580652147528089,-0.04241010240522003,0.12885737883854684,-1.3486765207435136,1.269449542990556,-0.10633468895957496,0.8693977289284917,0.4966058497171867,3.993132131516715,-1.548678875208257,1.0243308327237213,0.6057338953933035,-0.5073057591164345,1.5391168723820783,-0.10633468895957496,-0.5282207546911941,0.9135801145844248,-0.8190021137923701,1.2247336356763627,-1.4689320442427707,-0.12760615078476442,2.40815588672373,0.2580652147528089,-0.5491166052451673,1.0687484169607406,-0.6116888886017858,0.19338072765197223,0.21492436389411237
3,430
Selective autophagy
9
30
2.045425
0.040813
P12235,Q96HY6,O94874,Q14457,Q9Y3C8,Q9UBN7,Q16543,Q99623,P21796
Processes and pathways
GO Biological process
msigdb_gobp
406,104,200,358,171,246,340,89,249
1740,450,1162,200,1235,2302,2331,406,249,1169,3331,690,1337,2409,358,340,1054,1855,1250,2349,104,89,2153,2815,246,171,2229,2968,3267,2058
-0.08504483643208101,0.9578299883515244,0.2796623627116229,1.5616944426854624,0.23648587072936555,-0.4234551139739826,-0.44444629644309747,1.0243308327237213,1.3815262161857498,0.2796623627116229,-1.6874093080839918,0.6495063733352072,0.17185499556109507,-0.4863716580376144,1.1132326864910351,1.1577834161963467,0.3662283341069291,-0.14885918591010985,0.23648587072936555,-0.44444629644309747,2.0624235558075372,2.177283285595381,-0.31821572844136564,-0.7570132956764223,1.4039905186201218,1.7201861433390337,-0.36036802408587215,-0.9013775888027895,-1.4289311687084396,-0.254846688969337
3,430
The citric acid tca cycle and respiratory electron transport
27
98
2.042873
0.041065
O75964,P48047,O43676,P51970,P14927,O75306,Q16718,P36542,P35613,P56385,P06576,Q9P0J0,Q9UDW1,Q15120,Q9Y6M9,Q8N183,Q9NPL8,O43837,Q86Y39,P08574,P22695,P13073,P24539,P14854,P25705,P03886,P21796
Processes and pathways
Reactome Pathways
msigdb_reactome
2,521,4,397,14,514,146,281,26,412,40,45,579,570,449,68,476,336,352,223,232,108,109,484,501,500,249
656,1592,2858,1367,4,3021,2902,2025,336,2587,514,2369,2431,1435,710,1234,793,2,1514,3175,2060,2478,1515,3039,558,500,40,3131,2772,1841,223,2268,1663,3057,1664,2773,108,2884,484,14,3211,3142,659,249,2332,232,1991,109,501,2886,2483,1473,26,281,905,2946,2908,739,1713,521,1794,3168,3124,2440,1524,397,2521,2067,3294,412,1083,3303,694,884,1966,570,1601,146,2529,1180,2736,1821,352,68,919,1058,2540,2981,687,3101,1191,2428,476,813,45,2876,579,449
0.6933477721843095,0.0002977667180233936,-0.8190021137923701,0.15034720133396523,4.551842722059264,-0.9834347839005033,-0.8602294627439812,-0.254846688969337,1.1577834161963467,-0.5908507122210328,0.8693977289284917,-0.4654184907728244,-0.5073057591164345,0.10738556209941592,0.6276115039211269,0.23648587072936555,0.5620305844376072,5.167196520160504,0.06449608277835585,-1.2074277428722162,-0.2759883981888322,-0.5282207546911941,0.06449608277835585,-1.0038990229805613,0.8032512025014997,0.8914804711800896,2.8041124444238252,-1.1262605148954412,-0.736311113618571,-0.14885918591010985,1.448967877539575,-0.40244498209708657,-0.04241010240522003,-1.024343149410197,-0.04241010240522003,-0.736311113618571,2.0394981091593998,-0.8396256696385406,0.9135801145844248,3.537101859755954,-1.2882658134684348,-1.1465830158056964,0.6933477721843095,1.3815262161857498,-0.44444629644309747,1.4264710812485106,-0.23368633339360326,2.0394981091593998,0.8914804711800896,-0.8396256696385406,-0.5282207546911941,0.0859317852989234,3.0154764528966274,1.269449542990556,0.4748324586170831,-0.9013775888027895,-0.8602294627439812,0.6057338953933035,-0.06373662902854216,0.8693977289284917,-0.10633468895957496,-1.1871666764907194,-1.1059176287710073,-0.5073057591164345,0.06449608277835585,1.0465312750378557,-0.5491166052451673,-0.2759883981888322,-1.548678875208257,1.0243308327237213,0.34456029993080256,-1.5685621747527327,0.6495063733352072,0.4966058497171867,-0.21250736851480986,0.8032512025014997,0.0002977667180233936,1.8111031480459492,-0.5491166052451673,0.2796623627116229,-0.6948481366740377,-0.12760615078476442,1.1354997578192654,2.431327036159296,0.4748324586170831,0.3662283341069291,-0.5491166052451673,-0.9219218352181526,0.6714184729428473,-1.0651708848393058,0.2796623627116229,-0.4863716580376144,0.9356966299859146,0.5620305844376072,2.7105571292304815,-0.8190021137923701,0.8032512025014997,0.9799801607699364
3,430
Epistaxis
6
14
2.04075
0.041276
P49257,P04062,Q14980,O15460,P35579,P12814
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
562,167,456,391,444,466
391,2301,167,2557,1236,466,444,643,2168,562,456,1688,1198,1507
1.0465312750378557,-0.4234551139739826,1.7201861433390337,-0.569993271061387,0.23648587072936555,0.9356966299859146,0.9799801607699364,0.7152942406319166,-0.3393012744587857,0.8032512025014997,0.9578299883515244,-0.04241010240522003,0.2796623627116229,0.0859317852989234
3,430
EF-hand domain pair [IPR011992]
16
57
2.036502
0.0417
Q15293,P14314,Q9H223,Q99584,O43707,Q14257,O43852,Q9H4M9,P41208,P46939,Q9NWM8,Q9BRK5,P0DP25,Q13813,Q9UPN3,P80303
Sequence
InterPro Superfamily
interpro_homologous_superfamily
457,164,73,42,289,236,48,344,19,425,421,23,338,119,321,62
289,48,1288,1462,1985,638,3398,1987,1955,338,466,3399,164,877,2655,2061,2945,3301,1371,2437,19,2630,2841,425,743,2411,62,2832,2240,119,236,1445,457,2114,1722,1350,2453,2116,1529,1563,2455,1930,2688,3019,1311,42,23,73,344,954,421,1121,632,3406,2546,321,789
1.2470833648713042,2.6638687791403814,0.19338072765197223,0.0859317852989234,-0.23368633339360326,0.7152942406319166,-2.534175143153114,-0.23368633339360326,-0.21250736851480986,1.1577834161963467,0.9356966299859146,-2.5528891708295545,1.742891610000047,0.4966058497171867,-0.6325077598761806,-0.2759883981888322,-0.9013775888027895,-1.5685621747527327,0.15034720133396523,-0.5073057591164345,3.204350628748325,-0.6116888886017858,-0.7983588379042941,1.0021471184507622,0.6057338953933035,-0.4863716580376144,2.4545133476558236,-0.7776958844485033,-0.38141593935161383,1.9708151956500113,1.4264710812485106,0.10738556209941592,0.9578299883515244,-0.2971114238181862,-0.06373662902854216,0.17185499556109507,-0.5073057591164345,-0.2971114238181862,0.06449608277835585,0.04307848903912287,-0.5073057591164345,-0.191309831206804,-0.6533072855099272,-0.9629504767360699,0.19338072765197223,2.8041124444238252,3.109797184993122,2.40815588672373,1.1577834161963467,0.45307654705381356,1.0243308327237213,0.3229099381780773,0.7372578479891295,-3.012537226216726,-0.5491166052451673,1.2024003828056788,0.5838735785783277
3,430