term stringlengths 2 121 | overlap int64 6 281 | setsize int64 7 499 | score float64 1.96 10.6 | pval float64 0 0.05 | edge stringlengths 41 1.97k | type stringclasses 5
values | subtype stringclasses 24
values | subtype_key stringclasses 24
values | edge_idxs stringlengths 11 1.17k | ann_idxs stringlengths 19 2.31k | ann_vals stringlengths 124 9.94k | sig_size int64 2.2k 3.73k |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Micromelia | 8 | 24 | 2.064087 | 0.039009 | P48735,Q15392,Q96HY6,Q9UHX1,O43175,Q14739,Q9UBM7,O75874 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 129,34,294,8,232,50,154,286 | 744,3218,232,2725,2044,2630,361,286,516,589,129,1591,537,1777,50,34,2175,2297,294,1909,154,8,1097,3355 | 0.38894919874105743,-1.0027041076562464,1.400546940102355,-0.5995724062727221,-0.28358176189719153,-0.5503155785430718,0.9592374039290533,1.1924031585962547,0.6556730905320322,0.5452985658990057,1.9852909461843653,-0.09381103021537567,0.6336831437767028,-0.16457479426822091,3.1189087835415297,3.583187167896173,-0.33156... | 3,430 |
Organic acid transmembrane transport | 8 | 29 | 2.060106 | 0.039388 | P08183,Q9BQT8,O43772,P23786,Q9H2D1,Q9Y619,Q9UBX3,O14678 | Processes and pathways | GO Biological process | msigdb_gobp | 323,486,109,270,151,57,189,466 | 466,109,2935,699,1985,1520,856,323,1988,1338,270,1192,504,2642,2218,2381,1657,1247,964,1121,773,827,486,151,1903,1326,189,977,57 | 0.7432157338415764,2.1420351304999743,-0.7237852836123975,0.4338422448747199,-0.25967184066824295,-0.07032759590587762,0.2986183093020084,1.0445510616836513,-0.25967184066824295,0.02309332399172761,1.2552190861703458,0.09263033605246422,0.6776210718932071,-0.5503155785430718,-0.35564345936189407,-0.42821167915506675,-0... | 3,430 |
Disproportionate short limb short stature | 11 | 24 | 2.043628 | 0.04099 | Q96MF7,Q15392,P42345,Q7LGA3,Q9UBN7,Q14739,O75718,Q32P28,Q6DKJ4,P10644,Q9UBM7 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 290,34,482,171,500,50,361,247,117,589,154 | 1183,606,3218,2630,361,589,3244,482,1864,1118,1664,1828,50,34,247,117,171,2297,2610,290,1909,154,500,1467 | 0.09263033605246422,0.5230949161824157,-1.0027041076562464,-0.5503155785430718,0.9592374039290533,0.5452985658990057,-1.0542934068429035,0.7213921450541884,-0.2120155691768394,0.1387416835614649,-0.11734646334023954,-0.18826843715602568,3.1189087835415297,3.583187167896173,1.338473936006947,2.083474851760708,1.70635697... | 3,430 |
Slender long bone | 7 | 15 | 2.042707 | 0.041081 | Q96MF7,Q96J02,P37268,Q32P28,Q96L58,Q9Y487,Q9Y619 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 290,295,385,247,215,24,57 | 516,2161,385,2341,247,2958,1962,295,215,290,1323,1047,1620,24,57 | 0.6556730905320322,-0.33156716576876,0.9163495326117879,-0.4039652952055236,1.338473936006947,-0.7237852836123975,-0.23581657417804916,1.171392087430195,1.4828295622266432,1.1924031585962547,0.04632210615831087,0.18465877239643577,-0.09381103021537567,4.186254663337337,2.8994929547828066 | 3,430 |
Intrinsic component of mitochondrial inner membrane | 19 | 30 | 2.042379 | 0.041114 | Q8NE86,Q5XKP0,Q16891,Q9Y512,Q6P4A7,Q99595,Q9NVH1,Q9NX63,Q96NB2,Q13505,Q6UXV4,Q9Y2R0,Q16134,Q15070,O60830,O43819,Q9H9P8,O14925,O75880 | Localization | GO Cellular component | msigdb_gocc | 899,896,405,546,277,157,829,298,827,596,844,81,224,350,97,360,777,122,752 | 122,360,97,1335,752,1520,2643,2908,1350,596,350,224,405,1305,896,277,844,899,827,157,2661,3394,1326,777,829,298,2307,81,948,546 | 2.0442894948035293,0.9592374039290533,2.3161817108012213,0.02309332399172761,0.38894919874105743,-0.07032759590587762,-0.5503155785430718,-0.6988183969795223,0.02309332399172761,0.5452985658990057,0.9806232501634713,1.4417564181063023,0.8733052663722602,0.04632210615831087,0.2759203789757193,1.2343164607296082,0.321269... | 3,430 |
Abnormal arterial physiology | 7 | 30 | 2.040948 | 0.041256 | Q9NWM8,Q9NZ08,O75844,P01889,P05067,Q14739,P06280 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 137,299,139,329,46,50,156 | 1573,434,1576,550,2937,139,329,954,2680,46,156,2161,2904,2482,1705,2828,1653,2165,1530,1660,1533,50,707,2011,2014,137,299,2089,1229,657 | -0.09381103021537567,0.8084416390325024,-0.09381103021537567,0.6116509767559337,-0.7237852836123975,1.9260244005596443,1.0232798624432902,0.23038416792428346,-0.5749138732638202,3.191306028311356,1.8066716660719826,-0.33156716576876,-0.6988183969795223,-0.4768775233718424,-0.1409342612489813,-0.6490720698046804,-0.1173... | 3,430 |
Phagocytic vesicle membrane | 7 | 23 | 2.034641 | 0.041887 | Q15907,Q03518,P01889,Q93050,P04439,Q9Y487,P13473 | Localization | GO Cellular component | msigdb_gocc | 389,74,329,45,335,24,217 | 985,1577,329,335,402,611,632,217,2904,1027,2057,1115,2538,2386,2167,921,74,1073,389,45,1322,2974,24 | 0.20754527371745304,-0.09381103021537567,1.0232798624432902,1.0019706637911983,0.8733052663722602,0.5230949161824157,0.5008477318133796,1.4623099427802935,-0.6988183969795223,0.18465877239643577,-0.28358176189719153,0.1387416835614649,-0.5012978577516536,-0.42821167915506675,-0.33156716576876,0.25317576686812393,2.6203... | 3,430 |
Retinal detachment | 7 | 16 | 2.033645 | 0.041987 | Q96MF7,Q99496,Q8NAT1,O43505,P04439,O75533,Q9H9S5 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 290,559,273,146,335,588,283 | 146,588,335,1705,1653,634,1533,922,1664,273,290,559,283,1626,1465,1693 | 1.866485968870282,0.5452985658990057,1.0019706637911983,-0.1409342612489813,-0.11734646334023954,0.5008477318133796,-0.07032759590587762,0.25317576686812393,-0.11734646334023954,1.2552190861703458,1.1924031585962547,0.6116509767559337,1.213377883648462,-0.09381103021537567,-0.02351528122041195,-0.11734646334023954 | 3,430 |
Hyperlipidemia | 10 | 30 | 2.033368 | 0.042015 | Q96MF7,P49257,Q92734,O43707,P50402,O75844,P23786,P28070,O95470,P06280 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 290,263,523,479,396,139,270,80,147,156 | 1853,479,1335,139,147,954,156,1583,1765,270,80,955,1389,3391,263,396,2218,2874,922,1664,1947,1258,557,523,1962,290,1794,977,1053,2931 | -0.2120155691768394,0.7213921450541884,0.02309332399172761,1.9260244005596443,1.866485968870282,0.23038416792428346,1.8066716660719826,-0.09381103021537567,-0.16457479426822091,1.2552190861703458,2.5638146678084146,0.23038416792428346,-0.00018569005958125493,-1.9788713010588765,1.2760859545124026,0.8948470616767685,-0.... | 3,430 |
Nuclear inner membrane | 7 | 23 | 2.029637 | 0.042393 | O76062,O75844,P50402,Q99720,Q14739,Q8IXM6,Q9H1E5 | Localization | GO Cellular component | msigdb_gocc | 69,139,396,47,50,242,279 | 139,69,628,564,1863,858,396,2387,1071,441,1663,866,50,1884,2124,242,3211,1791,47,1794,279,1416,2254 | 1.9260244005596443,2.714006070492743,0.5008477318133796,0.5895763319810627,-0.2120155691768394,0.2986183093020084,0.8948470616767685,-0.42821167915506675,0.16172434863187643,0.8084416390325024,-0.11734646334023954,0.2986183093020084,3.1189087835415297,-0.2120155691768394,-0.30754673593761184,1.359199686384635,-0.977013... | 3,430 |
Hallucinations | 9 | 48 | 2.027078 | 0.042654 | O00754,P07602,P50897,O75503,P35637,P05067,Q9BQE5,O60313,Q6DKK2 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 66,36,6,138,140,46,19,94,31 | 3343,915,66,811,94,1186,138,812,2678,213,46,36,2820,2323,730,2161,2437,2579,1586,2787,140,1068,412,1428,1026,2908,6,2832,1656,2166,2221,1944,2067,2391,3184,31,1205,2128,367,2460,3127,3393,19,1274,652,977,2197,2368 | -1.3431986759033332,0.25317576686812393,2.8070566341243905,0.3438753282799643,2.35457505060863,0.09263033605246422,1.9260244005596443,0.3438753282799643,-0.5749138732638202,1.4828295622266432,3.191306028311356,3.495034957042614,-0.6490720698046804,-0.4039652952055236,0.4114181815276483,-0.33156716576876,-0.452515610449... | 3,430 |
Signaling | 6 | 20 | 2.02303 | 0.04307 | O15173,P43490,Q8WUJ1,P17931,O00264,Q96PC5 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 344,11,76,301,239,193 | 239,344,2320,301,1391,11,1865,617,1248,2917,705,792,379,1206,76,1895,739,193,1615,2421 | 1.359199686384635,0.9806232501634713,-0.4039652952055236,1.1292601049826305,-0.00018569005958125493,4.864332563034109,-0.2120155691768394,0.5230949161824157,0.06950099771551356,-0.6988183969795223,0.4338422448747199,0.36643501064183787,0.937812905361756,0.09263033605246422,2.601516115344004,-0.2120155691768394,0.411418... | 3,430 |
Regulation of endothelial cell migration | 7 | 30 | 2.015566 | 0.043845 | P57105,P42785,Q8WTV0,P09429,P04083,P09601,Q9H6U6 | Processes and pathways | GO Biological process | msigdb_gobp | 227,38,71,363,83,20,419 | 1573,1232,1753,2523,660,83,1383,491,1758,363,20,632,2051,2160,2270,2824,1587,3111,2904,38,2793,227,2833,2446,1593,2393,71,1791,419,1414 | -0.09381103021537567,0.06950099771551356,-0.16457479426822091,-0.5012978577516536,0.4785567416325205,2.5260093370892096,-0.00018569005958125493,0.6995273401513898,-0.16457479426822091,0.9592374039290533,4.337593478683959,0.5008477318133796,-0.28358176189719153,-0.33156716576876,-0.3797760297676727,-0.6490720698046804,-... | 3,430 |
Mitochondrial membrane organization | 16 | 50 | 2.013402 | 0.044072 | Q9Y584,Q15070,Q9Y5J9,P0DP25,O95202,O14737,Q9NX63,O94826,Q16891,Q9P0J0,Q9Y5L4,Q9NS69,P45880,Q9UII2,Q9Y5Z4,O60313 | Processes and pathways | GO Biological process | msigdb_gobp | 96,350,225,324,383,70,298,233,405,211,183,23,26,222,322,94 | 809,70,94,1334,1335,233,383,2680,2049,661,1932,324,631,2737,2687,2944,2643,2644,26,1113,2792,1817,1297,617,596,350,405,1538,1305,896,844,714,1168,643,1083,2661,3394,23,829,298,211,222,2197,948,546,96,421,225,183,322 | 0.3438753282799643,2.6953211040640213,2.35457505060863,0.02309332399172761,0.02309332399172761,1.400546940102355,0.9163495326117879,-0.5749138732638202,-0.28358176189719153,0.4785567416325205,-0.23581657417804916,1.0445510616836513,0.5008477318133796,-0.5995724062727221,-0.5749138732638202,-0.7237852836123975,-0.550315... | 3,430 |
Mitochondrial fusion | 10 | 14 | 2.012271 | 0.044191 | Q9NQG6,P02786,Q9UJZ1,Q9NX63,Q8N2A8,Q8TB36,Q8NAN2,Q8IWA4,Q07812,O60313 | Processes and pathways | GO Biological process | msigdb_gobp | 259,728,697,298,427,368,51,714,617,94 | 94,728,617,1607,714,427,51,368,1793,259,298,697,948,834 | 2.35457505060863,0.4114181815276483,0.5230949161824157,-0.09381103021537567,0.4338422448747199,0.8301027868261046,3.1189087835415297,0.9592374039290533,-0.16457479426822091,1.296917258531428,1.1503444701717498,0.45622167162433763,0.25317576686812393,0.3438753282799643 | 3,430 |
Lysosomal transport | 9 | 44 | 2.011724 | 0.044249 | Q14108,P07602,O15118,Q9Y2T2,P11717,Q99523,Q96L92,P13473,Q9UNK0 | Processes and pathways | GO Biological process | msigdb_gobp | 130,36,164,106,330,78,188,217,260 | 809,2153,359,2315,164,1803,1285,1754,36,1584,611,330,217,1237,1296,2057,1115,2166,681,130,2174,2882,2701,684,933,2408,1732,188,3127,78,1044,1140,1221,1738,2358,652,1375,1178,1799,1279,1627,979,260,106 | 0.3438753282799643,-0.33156716576876,0.9592374039290533,-0.4039652952055236,1.7465774077703615,-0.18826843715602568,0.04632210615831087,-0.16457479426822091,3.495034957042614,-0.09381103021537567,0.5230949161824157,1.0232798624432902,1.4623099427802935,0.06950099771551356,0.04632210615831087,-0.28358176189719153,0.1387... | 3,430 |
Regulation of blood pressure | 6 | 19 | 2.006216 | 0.044833 | P42785,P09493,Q9UIQ6,Q9HB40,P42892,P09601 | Processes and pathways | GO Biological process | msigdb_gobp | 38,201,12,17,49,20 | 3352,1423,201,20,3160,503,38,49,2792,2793,2833,3237,999,793,1048,17,299,12,574 | -1.369914466388914,-0.02351528122041195,1.5645724906173264,4.337593478683959,-0.900350577456945,0.6776210718932071,3.441890793303961,3.1189087835415297,-0.6242916466860307,-0.6242916466860307,-0.6490720698046804,-1.0284638912585382,0.20754527371745304,0.36643501064183787,0.18465877239643577,4.454305506671291,1.15034447... | 3,430 |
Abnormal thoracic spine morphology | 7 | 31 | 2.000499 | 0.045446 | O00754,Q96J02,Q9UHX1,O75844,P08236,P04062,P51648 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 66,295,8,139,246,213,223 | 1573,982,66,2627,952,2630,587,139,1421,1930,954,213,813,246,758,1760,2580,3235,1817,223,1533,2499,2957,3212,1732,2555,2610,295,873,400,8 | -0.09381103021537567,0.20754527371745304,2.8070566341243905,-0.5503155785430718,0.23038416792428346,-0.5503155785430718,0.5452985658990057,1.9260244005596443,-0.02351528122041195,-0.23581657417804916,0.23038416792428346,1.4828295622266432,0.3438753282799643,1.338473936006947,0.38894919874105743,-0.16457479426822091,-0.... | 3,430 |
Platyspondyly | 13 | 35 | 1.998242 | 0.04569 | P48735,O00754,Q96HY6,Q9UBN7,Q14739,P08236,Q32P28,Q96AY3,P16278,Q96L58,Q6NUK1,Q6NUQ1,O75874 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 129,66,294,500,50,246,247,448,179,215,472,258,286 | 2624,66,3218,952,550,2630,286,2431,1930,1422,246,179,2980,3244,2440,1862,129,1591,995,921,1533,50,2957,247,792,472,258,1494,448,2610,294,215,2715,500,2309 | -0.5503155785430718,2.8070566341243905,-1.0027041076562464,0.23038416792428346,0.6116509767559337,-0.5503155785430718,1.1924031585962547,-0.4525156104496164,-0.23581657417804916,-0.02351528122041195,1.338473936006947,1.6457867663301875,-0.7488153183487716,-1.0542934068429035,-0.4525156104496164,-0.2120155691768394,1.98... | 3,430 |
Ventricular arrhythmia | 11 | 43 | 1.99733 | 0.045789 | P0DP25,P46976,P09493,P50402,O43772,P23786,P03886,P10253,P42892,O75306,P13473 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 324,331,201,396,109,270,15,144,49,309,217 | 109,2572,309,1637,394,954,15,755,1642,2820,201,324,144,631,217,2051,1856,2437,1763,270,1706,1068,2871,49,331,2114,2908,396,1299,2745,1947,894,1719,1038,1450,557,2608,1732,1134,623,1045,1794,3213 | 2.1420351304999743,-0.5257770590663371,1.0869803140135814,-0.11734646334023954,0.8948470616767685,0.23038416792428346,4.652417670407559,0.38894919874105743,-0.11734646334023954,-0.6490720698046804,1.5645724906173264,1.0445510616836513,1.8863625663085712,0.5008477318133796,1.4623099427802935,-0.28358176189719153,-0.2120... | 3,430 |
Abnormal delivery | 7 | 22 | 1.996593 | 0.045869 | O75844,Q6YHK3,O75718,Q9Y487,Q9UBM7,O60313,Q9Y619 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 139,463,361,24,154,94,57 | 1853,94,361,139,3220,954,813,2161,2326,1591,1027,483,1533,463,1833,3211,1501,1458,2087,154,24,57 | -0.2120155691768394,2.35457505060863,0.9592374039290533,1.9260244005596443,-1.0027041076562464,0.23038416792428346,0.3438753282799643,-0.33156716576876,-0.4039652952055236,-0.09381103021537567,0.18465877239643577,0.7213921450541884,-0.07032759590587762,0.7649983512811526,-0.18826843715602568,-0.977013463993979,-0.04689... | 3,430 |
Ascites | 9 | 29 | 1.994534 | 0.046094 | Q14108,P61916,P63241,O15118,Q14739,P08236,P04062,Q13510,Q01844 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 130,256,347,164,50,246,213,313,124 | 164,786,2261,1472,2781,213,246,589,788,2822,2271,3391,2165,1941,256,347,593,1394,124,1662,1713,313,130,50,1829,381,2145,1909,3048 | 1.7465774077703615,0.36643501064183787,-0.3797760297676727,-0.04689579872958434,-0.6242916466860307,1.4828295622266432,1.338473936006947,0.5452985658990057,0.36643501064183787,-0.6490720698046804,-0.3797760297676727,-1.9788713010588765,-0.33156716576876,-0.23581657417804916,1.296917258531428,0.9806232501634713,0.545298... | 3,430 |
Telangiectasia | 8 | 38 | 1.99259 | 0.046306 | Q13535,P03886,Q8IZA0,Q14739,O75306,O95453,P10619,P06280 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 348,15,272,50,309,119,25,156 | 1805,2861,309,953,119,954,15,156,2434,25,2375,2324,758,1760,2824,1763,955,1705,3247,1814,2444,1866,537,1713,1250,1664,348,50,2174,2014,272,739,2559,381,2611,2142,3008,2420 | -0.18826843715602568,-0.6739141572295496,1.0869803140135814,0.23038416792428346,2.063896781548296,0.23038416792428346,4.652417670407559,1.8066716660719826,-0.4525156104496164,4.1354813465701925,-0.42821167915506675,-0.4039652952055236,0.38894919874105743,-0.16457479426822091,-0.6490720698046804,-0.16457479426822091,0.2... | 3,430 |
Severe short stature | 7 | 24 | 1.980543 | 0.047643 | Q96MF7,Q15392,P16278,Q96L58,P53701,Q9Y619,P10619 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 290,34,179,215,276,57,25 | 3218,2897,2630,25,179,1763,2440,2583,1862,2643,994,634,276,840,537,34,2958,3170,1501,294,215,290,1323,57 | -1.0027041076562464,-0.6988183969795223,-0.5503155785430718,4.1354813465701925,1.6457867663301875,-0.16457479426822091,-0.4525156104496164,-0.5257770590663371,-0.2120155691768394,-0.5503155785430718,0.20754527371745304,0.5008477318133796,1.2343164607296082,0.32126985958171844,0.6336831437767028,3.583187167896173,-0.723... | 3,430 |
Azurophil granule membrane | 7 | 22 | 1.976785 | 0.048066 | P07602,P42785,Q07065,P10253,O15260,Q9NQX7,P13473 | Localization | GO Cellular component | msigdb_gocc | 36,38,113,144,149,220,217 | 149,2629,3157,1186,36,144,611,217,2112,38,2163,1115,113,1078,1729,341,3282,3171,1010,220,652,1973 | 1.8465787199040886,-0.5503155785430718,-0.900350577456945,0.09263033605246422,3.495034957042614,1.8863625663085712,0.5230949161824157,1.4623099427802935,-0.30754673593761184,3.441890793303961,-0.33156716576876,0.1387416835614649,2.122543890584666,0.16172434863187643,-0.1409342612489813,1.0019706637911983,-1.10616404523... | 3,430 |
Protein localization to mitochondrion | 21 | 59 | 1.973948 | 0.048388 | O43615,P49257,Q9NS69,P55786,Q9Y5J7,Q99595,Q9Y5L4,P0DP25,O14737,Q99797,Q9P0J0,Q9UII2,Q8N4H5,Q9Y584,Q15070,Q9Y5J9,O60830,O94826,Q8TB36,O14925,Q5JRX3 | Processes and pathways | GO Biological process | msigdb_gobp | 134,263,23,152,421,157,183,324,70,199,211,222,95,96,350,225,97,233,368,122,126 | 2773,809,915,70,122,134,97,1578,233,2631,1289,1700,1930,2678,661,324,3085,435,2376,3142,2687,1194,1810,2944,263,2792,2380,1297,152,2914,617,1157,350,820,2802,1538,1305,126,1607,95,368,1083,559,157,199,649,1412,23,211,3290,222,2197,3284,546,96,421,225,183,834 | -0.6242916466860307,0.3438753282799643,0.25317576686812393,2.6953211040640213,2.0442894948035293,1.965565398534416,2.3161817108012213,-0.09381103021537567,1.400546940102355,-0.5503155785430718,0.04632210615831087,-0.1409342612489813,-0.23581657417804916,-0.5749138732638202,0.4785567416325205,1.0445510616836513,-0.82428... | 3,430 |
Muscle abnormality related to mitochondrial dysfunction | 10 | 37 | 1.97344 | 0.048446 | O43676,Q96CU9,Q9Y6M9,P14854,P00403,P03886,Q9Y2R0,O75306,Q9UBX3,O60313 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 35,103,373,424,394,15,81,309,189,94 | 698,2257,35,94,2104,309,1697,1920,1062,3219,610,394,15,631,424,2578,2736,1863,3196,2116,1305,474,898,2182,1893,103,1134,2891,2469,2764,875,721,189,81,2721,1570,373 | 0.4338422448747199,-0.3797760297676727,3.512707326927762,2.35457505060863,-0.30754673593761184,1.0869803140135814,-0.1409342612489813,-0.23581657417804916,0.16172434863187643,-1.0027041076562464,0.5230949161824157,0.8948470616767685,4.652417670407559,0.5008477318133796,0.8301027868261046,-0.5257770590663371,-0.59957240... | 3,430 |
Hexosyltransferase activity | 12 | 36 | 1.968081 | 0.049059 | Q6ZXV5,P06865,Q2TAA5,P46976,Q13126,Q8NAT1,O43505,O60512,P04062,Q96L58,Q8N4A0,Q10472 | Functions | GO Molecular function | msigdb_gomf | 289,99,556,331,205,273,146,150,213,215,281,469 | 2624,1982,146,952,150,550,1805,2523,213,917,1384,1583,99,918,2159,1645,1389,331,1815,1533,1662,732,469,205,556,289,1126,281,273,1263,1673,215,941,1970,3416,782 | -0.5503155785430718,-0.25967184066824295,1.866485968870282,0.23038416792428346,1.8465787199040886,0.6116509767559337,-0.18826843715602568,-0.5012978577516536,1.4828295622266432,0.25317576686812393,-0.00018569005958125493,-0.09381103021537567,2.277678317409277,0.25317576686812393,-0.33156716576876,-0.11734646334023954,-... | 3,430 |
Metatarsus adductus | 6 | 13 | 1.960521 | 0.049935 | O96028,Q15392,O95202,P08236,Q96L58,Q9UBM7 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 191,34,383,246,215,154 | 383,191,246,1650,1817,441,1869,2797,34,215,1047,154,2974 | 0.9163495326117879,1.6052450348577447,1.338473936006947,-0.11734646334023954,-0.18826843715602568,0.8084416390325024,-0.2120155691768394,-0.6242916466860307,3.583187167896173,1.4828295622266432,0.18465877239643577,1.826640669391119,-0.7237852836123975 | 3,430 |
Lumenal side of endoplasmic reticulum membrane | 6 | 8 | 2.484994 | 0.012955 | Q8TCT9,P04439,P01889,P27824,P51572,P10321 | Localization | GO Cellular component | msigdb_gocc | 70,168,269,270,340,158 | 343,269,168,158,1352,270,340,70 | 1.0364629614668819,1.2630600632743048,1.6610108338836194,1.757884300742988,0.06407338100523642,1.2630600632743048,1.057305181951178,2.553352994479783 | 3,430 |
Antigen processing and presentation of endogenous peptide antigen | 7 | 9 | 2.462907 | 0.013782 | Q03519,Q6P179,P04439,P01889,Q03518,Q9NZ08,P10321 | Processes and pathways | GO Biological process | msigdb_gobp | 129,293,168,269,112,24,158 | 343,269,168,158,1677,112,129,293,24 | 1.0364629614668819,1.2630600632743048,1.6610108338836194,1.757884300742988,-0.10213768578822673,2.061430403594576,1.891865759389253,1.1813305049758258,3.553979031490054 | 3,430 |
Antigen processing and presentation of endogenous antigen | 7 | 9 | 2.462907 | 0.013782 | Q03519,Q6P179,P04439,P01889,Q03518,Q9NZ08,P10321 | Processes and pathways | GO Biological process | msigdb_gobp | 129,293,168,269,112,24,158 | 343,269,168,158,1677,112,129,293,24 | 1.0364629614668819,1.2630600632743048,1.6610108338836194,1.757884300742988,-0.10213768578822673,2.061430403594576,1.891865759389253,1.1813305049758258,3.553979031490054 | 3,430 |
Antiporter activity | 6 | 8 | 2.253867 | 0.024205 | P12236,P05141,Q02978,P12235,Q9UBX3,P08195 | Functions | GO Molecular function | msigdb_gomf | 320,357,396,319,92,287 | 392,357,287,319,320,2352,396,92 | 0.9314960696962661,1.015570844477996,1.2018332759105956,1.0988413665209409,1.0988413665209409,-0.3959200417834923,0.9314960696962661,2.283047194513152 | 3,430 |
Porphyrin and chlorophyll metabolism | 7 | 14 | 2.172429 | 0.029823 | P36551,P30519,P09601,P22830,Q5JPH6,P08236,Q96EY8 | Processes and pathways | KEGG Pathways | msigdb_kegg | 99,5,101,11,240,205,310 | 1111,1350,205,2295,101,11,5,99,2188,1357,306,240,1056,310 | 0.20374464368210365,0.06407338100523642,1.503894702163965,-0.3709853125137018,2.172859102163878,4.107772994111282,5.03017478838894,2.2097242428181456,-0.32137042377466907,0.06407338100523642,1.1401822218335855,1.3641854583979733,0.24975397691551138,1.1401822218335855 | 3,430 |
Mhc protein binding | 7 | 11 | 2.131278 | 0.033066 | P06576,Q03519,Q03518,P51572,O15533,Q9NUQ9,P25705 | Functions | GO Molecular function | msigdb_gomf | 225,129,112,340,343,28,254 | 343,225,1479,254,340,624,2249,112,129,377,28 | 1.0364629614668819,1.4043211024190974,-0.006717839319282361,1.3036465389571528,1.057305181951178,0.5866553931117515,-0.34613573151426974,2.061430403594576,1.891865759389253,0.973635461621998,3.407140852160664 | 3,430 |
Mhc class i protein binding | 6 | 10 | 2.05678 | 0.039707 | P06576,Q03519,Q03518,P51572,O15533,P25705 | Functions | GO Molecular function | msigdb_gomf | 225,129,112,340,343,254 | 343,225,1479,254,340,624,2249,112,129,377 | 1.0364629614668819,1.4043211024190974,-0.006717839319282361,1.3036465389571528,1.057305181951178,0.5866553931117515,-0.34613573151426974,2.061430403594576,1.891865759389253,0.973635461621998 | 3,430 |
Tetrapyrrole binding | 11 | 18 | 2.052407 | 0.04013 | P30519,P09601,O43169,Q16850,O15173,Q8WUJ1,P08574,O00264,Q96EY8,P53701,Q6UW02 | Functions | GO Molecular function | msigdb_gomf | 5,101,38,170,141,44,143,146,310,306,97 | 146,141,38,143,101,304,5,306,170,97,1056,44,310,1516,480,855,2473,2064 | 1.8155355874645718,1.8537767842690276,3.208299500767211,1.83467532885005,2.172859102163878,1.1401822218335855,5.03017478838894,1.1401822218335855,1.6610108338836194,2.2464531018578775,0.24975397691551138,2.9030839669015975,1.1401822218335855,-0.006717839319282361,0.7823570787372804,0.3862050876012223,-0.446048521945655... | 3,430 |
Processing of smdt1 | 6 | 10 | 2.0309 | 0.042265 | Q8IYU8,Q8WWC4,Q9Y4W6,Q99623,Q9UJZ1,O75439 | Processes and pathways | Reactome Pathways | msigdb_reactome | 259,49,281,217,224,285 | 285,1636,397,259,635,49,918,217,224,281 | 1.2018332759105956,-0.07817009911541081,0.9314960696962661,1.3036465389571528,0.5866553931117515,2.816737247023802,0.3409796634418964,1.4442806151058643,1.4243227288831315,1.2426977300728366 | 3,430 |
Mitochondrial carrier protein [IPR002067] | 8 | 10 | 2.019997 | 0.043384 | P12236,P12235,P05141,O75746,Q9H936,P53007,Q9UJS0,Q9BQT8 | Sequence | InterPro Family | interpro_family | 320,319,357,484,469,525,446,58 | 591,484,357,319,320,525,973,58,469,446 | 0.6086282374406464,0.7608365031739326,1.015570844477996,1.0988413665209409,1.0988413665209409,0.6959430870585518,0.29549744978102077,2.6770943999274905,0.8038230816292831,0.8465930328531754 | 3,430 |
Acyl-CoA dehydrogenase-like, C-terminal [IPR036250] | 6 | 9 | 2.017607 | 0.043632 | Q709F0,O15254,Q9H845,Q15067,P26440,P11310 | Sequence | InterPro Superfamily | interpro_homologous_superfamily | 491,380,72,107,434,219 | 380,219,434,842,490,107,491,951,72 | 0.9525914548719056,1.4243227288831315,0.8465930328531754,0.3862050876012223,0.7608365031739326,2.098713770993166,0.7608365031739326,0.31827093163679243,2.5355539747519957 | 3,430 |
Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily [IPR009100] | 6 | 9 | 2.017607 | 0.043632 | Q709F0,O15254,Q9H845,Q15067,P26440,P11310 | Sequence | InterPro Superfamily | interpro_homologous_superfamily | 491,380,72,107,434,219 | 380,219,434,842,490,107,491,951,72 | 0.9525914548719056,1.4243227288831315,0.8465930328531754,0.3862050876012223,0.7608365031739326,2.098713770993166,0.7608365031739326,0.31827093163679243,2.5355539747519957 | 3,430 |
Acyl-CoA oxidase/dehydrogenase, central domain [IPR006091] | 6 | 9 | 2.017607 | 0.043632 | Q709F0,O15254,Q9H845,Q15067,P26440,P11310 | Sequence | InterPro Domain | interpro_domain | 491,380,72,107,434,219 | 380,219,434,842,490,107,491,951,72 | 0.9525914548719056,1.4243227288831315,0.8465930328531754,0.3862050876012223,0.7608365031739326,2.098713770993166,0.7608365031739326,0.31827093163679243,2.5355539747519957 | 3,430 |
Abc type transporter activity | 6 | 10 | 2.003767 | 0.045095 | Q9HD20,Q03519,P08183,Q03518,O75027,O15533 | Functions | GO Molecular function | msigdb_gomf | 197,129,410,112,213,343 | 1880,343,213,410,761,112,129,197,1464,501 | -0.1987783830519874,1.0364629614668819,1.4442806151058643,0.8891496313255574,0.4535712115110452,2.061430403594576,1.891865759389253,1.5434239324829382,0.0169517671877368,0.7392609323561437 | 3,430 |
Ketoacidosis | 7 | 10 | 1.985296 | 0.047112 | P35610,P09001,P08574,P53985,Q9HCC0,P22033,Q4G176 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 230,424,143,209,184,304,221 | 143,424,304,1899,434,230,209,2972,221,184 | 1.83467532885005,0.8678977997586717,1.1401822218335855,-0.1987783830519874,0.8465930328531754,1.3842754439377112,1.464195049648795,-0.7808039974572951,1.4243227288831315,1.6024030309091215 | 3,430 |
Inner mitochondrial membrane protein complex | 33 | 76 | 4.050584 | 0.000051 | O75964,P48047,O43676,P51970,P14927,O75306,Q16718,P36542,P20674,O00217,P56385,P06576,Q9P0J0,Q99595,Q9UDW1,Q9NX63,O60830,P14406,P00403,Q9Y6M9,O75489,Q13505,Q99623,O75431,Q86Y39,P08574,P22695,P13073,Q16891,P24539,P14854,P25705,P03886 | Localization | GO Cellular component | msigdb_gocc | 2,521,4,397,14,514,146,281,659,656,412,40,45,703,579,578,56,560,558,449,710,588,89,219,352,223,232,108,360,109,484,501,500 | 656,2858,2585,1367,4,3021,56,2587,514,2369,219,1435,710,793,2,1514,3175,2060,1515,558,500,40,223,1663,1664,1811,108,560,484,14,3211,3142,659,2332,232,109,501,2886,2483,1473,1400,281,1814,1713,521,3124,397,3294,412,588,146,1180,360,1967,2634,2755,1999,352,1529,1419,1092,1763,703,89,3129,760,1319,578,45,579,1590,895,819,... | 0.6933477721843095,-0.8190021137923701,-0.5908507122210328,0.15034720133396523,4.551842722059264,-0.9834347839005033,2.547409768053795,-0.5908507122210328,0.8693977289284917,-0.4654184907728244,1.4714808810674698,0.10738556209941592,0.6276115039211269,0.5620305844376072,5.167196520160504,0.06449608277835585,-1.20742774... | 3,430 |
Mitochondrial transport | 30 | 85 | 3.615441 | 0.0003 | Q14849,O75964,P48047,Q9NS69,Q10713,P36542,P56385,P51572,P12235,Q99797,P06576,Q8N4H5,Q96EK5,Q9P0J0,O60830,Q9UBX3,Q8TB36,P07900,P49257,O14737,Q9Y5J9,Q15070,O75431,Q9Y5Z4,Q9UII2,P24539,Q9Y5L4,Q96QK1,Q9UJZ1,P25705 | Processes and pathways | GO Biological process | msigdb_gobp | 1,2,521,7,414,281,412,410,406,438,40,546,548,45,56,320,191,314,562,206,84,589,219,94,363,109,114,507,390,501 | 984,206,2585,1546,3375,56,709,219,2300,793,2,987,2098,2477,1235,2770,3130,2302,2331,40,314,1629,901,406,936,713,109,501,3059,1667,2592,1746,281,2560,603,521,1295,562,3094,2236,410,2948,1111,3294,412,1405,995,414,1,589,2754,1051,1967,2634,1684,1722,1250,2453,2116,546,191,2118,548,507,2577,703,438,1188,760,2390,7,45,2191... | 0.4096172898409424,1.5165554046538223,-0.5908507122210328,0.04307848903912287,-2.0198432297961233,2.547409768053795,0.6276115039211269,1.4714808810674698,-0.4234551139739826,0.5620305844376072,5.167196520160504,0.4096172898409424,-0.2971114238181862,-0.5282207546911941,0.23648587072936555,-0.736311113618571,-1.12626051... | 3,430 |
Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins | 31 | 63 | 3.470842 | 0.000519 | O75964,P48047,O43676,P51970,P14927,O75306,Q16718,P36542,P20674,Q9P032,O00217,Q9BQ95,P56385,P06576,Q9P0J0,Q9UDW1,Q12931,P00403,Q9Y6M9,Q8N183,O75489,Q9NPL8,Q86Y39,P08574,P22695,P13073,P24539,P14854,P42704,P25705,P03886 | Processes and pathways | Reactome Pathways | msigdb_reactome | 2,521,4,397,14,514,146,281,659,813,656,687,412,40,45,579,694,558,449,68,710,476,352,223,232,108,109,484,739,501,500 | 656,2858,1367,4,3021,2025,2587,514,2369,1435,710,1234,793,2,1514,3175,2060,1515,558,500,40,223,1663,1664,108,2884,484,14,3211,3142,659,2332,232,109,501,2886,2483,1473,281,2946,739,1713,521,3124,397,3294,412,694,1601,146,1180,1821,352,68,1058,687,3101,1191,476,813,45,579,449 | 0.6933477721843095,-0.8190021137923701,0.15034720133396523,4.551842722059264,-0.9834347839005033,-0.254846688969337,-0.5908507122210328,0.8693977289284917,-0.4654184907728244,0.10738556209941592,0.6276115039211269,0.23648587072936555,0.5620305844376072,5.167196520160504,0.06449608277835585,-1.2074277428722162,-0.275988... | 3,430 |
Cilium assembly | 22 | 69 | 3.400179 | 0.000673 | O95613,P41208,Q10713,Q13561,P06493,Q9BV73,O15078,O94927,Q96A65,P61981,O60645,O75935,Q14203,P78371,P07900,P62258,Q9Y496,Q96KP1,Q9UPT5,Q9UBN7,Q99996,A6NIH7 | Processes and pathways | Reactome Pathways | msigdb_reactome | 515,19,414,415,543,309,173,175,307,427,423,443,188,446,314,67,205,492,113,246,387,127 | 790,127,844,173,821,423,1912,443,175,515,3005,1132,543,988,314,1632,1879,1551,2591,968,2273,19,1079,1521,679,1845,1815,2485,2103,1141,427,67,2991,2139,446,414,1406,415,1581,1526,188,833,569,1484,696,1216,1822,886,3272,780,1057,2002,1185,307,492,2123,387,1220,309,2083,3086,1863,956,2225,246,3246,113,1456,205 | 0.5620305844376072,1.9251046821425566,0.518396688704323,1.6748229295823038,0.5402049440683143,1.0021471184507622,-0.191309831206804,0.9799801607699364,1.6748229295823038,0.8693977289284917,-0.9629504767360699,0.3012772815040069,0.8252830651235218,0.4096172898409424,1.2024003828056788,-0.02106529204966477,-0.17009375816... | 3,430 |
Chaperone | 20 | 40 | 3.319791 | 0.000901 | Q04917,Q99426,P08238,P49368,P27348,Q99471,P31946,P61981,O60476,P63104,Q14203,Q12931,P07900,P78371,O75347,Q58FF6,P62258,Q9UHV9,Q14BN4,P61604 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 284,160,404,679,677,436,178,427,51,316,188,694,314,446,313,196,67,598,85,118 | 984,3166,2366,51,313,986,2557,314,404,1264,1551,677,1812,178,938,1521,679,1845,1815,118,2069,427,67,316,446,284,694,188,85,943,2681,196,2384,1686,160,436,1356,760,2263,598 | 0.4096172898409424,-1.1871666764907194,-0.4654184907728244,2.6172401968299104,1.2024003828056788,0.4096172898409424,-0.569993271061387,1.2024003828056788,1.0243308327237213,0.21492436389411237,0.04307848903912287,0.6714184729428473,-0.12760615078476442,1.6748229295823038,0.45307654705381356,0.06449608277835585,0.671418... | 3,430 |
Cardiac muscle contraction | 12 | 21 | 3.295296 | 0.000983 | P14406,P00403,P09493,P16615,P08574,P22695,P13073,P14854,P14927,P06753,P67936,Q9UDW1 | Processes and pathways | KEGG Pathways | msigdb_kegg | 560,558,3,602,223,232,108,484,14,176,16,579 | 1367,558,1261,176,223,3,1663,1664,108,560,484,14,3211,602,659,232,1473,1713,2275,16,579 | 0.15034720133396523,0.8032512025014997,0.21492436389411237,1.6748229295823038,1.448967877539575,4.649741438376801,-0.04241010240522003,-0.04241010240522003,2.0394981091593998,0.8032512025014997,0.9135801145844248,3.537101859755954,-1.2882658134684348,0.7592385640896675,0.6933477721843095,1.4264710812485106,0.0859317852... | 3,430 |
Mitochondrial respiratory chain complex assembly | 14 | 39 | 3.208843 | 0.001333 | Q9Y6M9,Q8N183,Q69YU5,O43676,Q86Y39,Q9H061,P51970,Q6DKK2,Q9P0J0,Q9Y2R0,Q00059,Q16718,P03886,Q9BSK2 | Processes and pathways | GO Biological process | msigdb_gobp | 449,68,35,4,352,39,397,267,45,49,50,146,500,287 | 656,4,3021,2025,2587,514,1435,710,1234,1514,2060,2770,1515,500,2886,1713,397,50,589,146,1180,35,267,1821,352,68,1058,1092,287,3101,39,1191,2852,813,45,1590,49,819,449 | 0.6933477721843095,4.551842722059264,-0.9834347839005033,-0.254846688969337,-0.5908507122210328,0.8693977289284917,0.10738556209941592,0.6276115039211269,0.23648587072936555,0.06449608277835585,-0.2759883981888322,-0.736311113618571,0.06449608277835585,0.8914804711800896,-0.8396256696385406,-0.06373662902854216,1.04653... | 3,430 |
Huntingtons disease | 32 | 81 | 3.151867 | 0.001622 | P48047,O43676,P51970,P14927,P27695,O75306,Q16718,P36542,P20674,O00291,P42574,O00217,Q13561,O15514,P12235,P06576,Q9UDW1,Q00059,Q14203,P14406,P00403,P42858,Q9Y6M9,O75489,P45880,P08574,P22695,P13073,P24539,P14854,P25705,P21796 | Processes and pathways | KEGG Pathways | msigdb_kegg | 521,4,397,14,641,514,146,281,659,531,533,656,415,163,406,40,579,50,188,560,558,690,449,710,603,223,232,108,109,484,501,249 | 656,531,2858,1367,163,4,3021,2587,514,2369,1435,710,793,1290,1514,3175,2060,1915,1515,558,3362,2302,2331,40,223,1019,2130,1663,1664,406,1811,108,560,484,14,3211,2133,1784,3142,659,249,2332,232,109,2270,501,641,2886,1048,2483,1473,281,533,690,603,1713,521,3124,397,770,3222,1207,50,745,995,1599,1408,415,188,3029,146,1180... | 0.6933477721843095,0.8473319171085857,-0.8190021137923701,0.15034720133396523,1.742891610000047,4.551842722059264,-0.9834347839005033,-0.5908507122210328,0.8693977289284917,-0.4654184907728244,0.10738556209941592,0.6276115039211269,0.5620305844376072,0.19338072765197223,0.06449608277835585,-1.2074277428722162,-0.275988... | 3,430 |
Organelle biogenesis and maintenance | 37 | 104 | 3.111571 | 0.001861 | O75964,P48047,P00367,O95613,P41208,Q10713,P54646,P36542,Q13561,P56385,P06493,P06576,Q04837,Q9BV73,O15078,O94927,Q96A65,Q00059,P61981,Q9NX63,Q15019,O60645,O75935,Q14203,P07900,P78371,P62258,Q9Y496,O75431,Q96KP1,Q16891,P24539,Q9UPT5,Q9UBN7,P25705,Q99996,A6NIH7 | Processes and pathways | Reactome Pathways | msigdb_reactome | 2,521,516,515,19,414,151,281,415,412,543,40,168,309,173,175,307,50,427,578,569,423,443,188,314,446,67,205,219,492,360,109,113,246,501,387,127 | 790,127,1366,844,173,821,423,2625,219,1912,443,793,2,175,515,3005,516,3362,1132,543,40,988,314,1632,1879,1551,2591,109,501,968,2273,281,1814,19,1079,521,1521,3168,679,1845,1815,3320,2485,1748,151,3294,412,2103,1141,427,67,2991,2139,446,50,168,414,1406,588,415,1581,1526,188,833,569,1484,2680,696,360,2755,1216,1999,1822,... | 0.5620305844376072,1.9251046821425566,0.15034720133396523,0.518396688704323,1.6748229295823038,0.5402049440683143,1.0021471184507622,-0.6116888886017858,1.4714808810674698,-0.191309831206804,0.9799801607699364,0.5620305844376072,5.167196520160504,1.6748229295823038,0.8693977289284917,-0.9629504767360699,0.8693977289284... | 3,430 |
Cis golgi network | 7 | 16 | 3.086715 | 0.002024 | P30533,Q9NPR9,Q14789,P24390,Q8TBA6,O00461,Q08379 | Localization | GO Cellular component | msigdb_gocc | 99,297,225,13,63,153,155 | 153,845,1130,13,99,992,155,225,1086,63,921,2002,2184,387,297,1946 | 1.7656129496664057,0.518396688704323,0.3012772815040069,3.5848660368475693,2.0853645337676863,0.4096172898409424,1.7656129496664057,1.448967877539575,0.34456029993080256,2.4545133476558236,0.4748324586170831,-0.23368633339360326,-0.3393012744587857,1.0687484169607406,1.2470833648713042,-0.191309831206804 | 3,430 |
Electron transport chain oxphos system in mitochondria | 21 | 52 | 3.063176 | 0.00219 | O75964,P48047,O43676,P51970,P14927,O75306,Q16718,P36542,P56385,P12235,P06576,Q9UDW1,P14406,Q9Y6M9,Q9UII2,P22695,P13073,P24539,P14854,P25705,P03886 | Processes and pathways | WikiPathways | msigdb_wp | 2,521,4,397,14,514,146,281,412,406,40,579,560,449,363,232,108,109,484,501,500 | 656,2858,1367,4,3021,2587,514,2369,1435,710,1234,793,2,1514,3175,2060,1515,558,500,2331,40,1663,1664,406,1811,108,560,484,14,3211,3142,659,2332,232,109,501,2886,2483,1473,281,1713,521,3124,397,3294,412,146,1180,2635,579,363,449 | 0.6933477721843095,-0.8190021137923701,0.15034720133396523,4.551842722059264,-0.9834347839005033,-0.5908507122210328,0.8693977289284917,-0.4654184907728244,0.10738556209941592,0.6276115039211269,0.23648587072936555,0.5620305844376072,5.167196520160504,0.06449608277835585,-1.2074277428722162,-0.2759883981888322,0.064496... | 3,430 |
Progeriaassociated lipodystrophy | 7 | 10 | 3.050848 | 0.002282 | Q03252,P28340,P49354,P20700,P02545,O75844,O60725 | Processes and pathways | WikiPathways | msigdb_wp | 34,254,203,77,46,322,86 | 86,2197,322,46,1262,77,254,407,203,34 | 2.177283285595381,-0.36036802408587215,1.1800836337709497,2.6872054940154664,0.21492436389411237,2.3156233598343645,1.359078200582899,1.0243308327237213,1.5391168723820783,2.8979047777720357 | 3,430 |
Intracellular calcium-sensing protein | 7 | 16 | 3.029964 | 0.002446 | Q99584,Q14257,O43852,P41208,P0DP25,Q9BRK5,P80303 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 42,236,48,19,338,23,62 | 48,338,1371,19,743,2411,62,2832,236,457,2714,1350,1529,1563,42,23 | 2.6638687791403814,1.1577834161963467,0.15034720133396523,3.204350628748325,0.6057338953933035,-0.4863716580376144,2.4545133476558236,-0.7776958844485033,1.4264710812485106,0.9578299883515244,-0.6740874247602239,0.17185499556109507,0.06449608277835585,0.04307848903912287,2.8041124444238252,3.109797184993122 | 3,430 |
Calmodulin | 7 | 16 | 3.029964 | 0.002446 | Q99584,Q14257,O43852,P41208,P0DP25,Q9BRK5,P80303 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 42,236,48,19,338,23,62 | 48,338,1371,19,743,2411,62,2832,236,457,2714,1350,1529,1563,42,23 | 2.6638687791403814,1.1577834161963467,0.15034720133396523,3.204350628748325,0.6057338953933035,-0.4863716580376144,2.4545133476558236,-0.7776958844485033,1.4264710812485106,0.9578299883515244,-0.6740874247602239,0.17185499556109507,0.06449608277835585,0.04307848903912287,2.8041124444238252,3.109797184993122 | 3,430 |
Establishment of protein localization to mitochondrial membrane | 6 | 19 | 3.027739 | 0.002464 | Q9NS69,Q9P0J0,O14737,Q9Y5L4,Q9Y5J9,P07900 | Processes and pathways | GO Biological process | msigdb_gobp | 7,45,206,114,84,314 | 1874,206,987,314,338,1667,1746,995,589,2634,2118,7,45,1590,819,843,1774,84,114 | -0.17009375816547115,1.5165554046538223,0.4096172898409424,1.2024003828056788,1.1577834161963467,-0.04241010240522003,-0.08504483643208101,0.4096172898409424,0.7812363588966038,-0.6116888886017858,-0.2971114238181862,4.283733422464173,2.7105571292304815,0.02167903874393584,0.5620305844376072,0.5402049440683143,-0.08504... | 3,430 |
Oxidative phosphorylation | 27 | 61 | 3.000293 | 0.002697 | O75964,P48047,O43676,P51970,P14927,O75306,Q16718,P36542,P20674,P56385,O00217,Q9Y5K8,P06576,Q9UDW1,P14406,P00403,Q9Y6M9,Q93050,Q9Y487,Q86Y39,P08574,P22695,P13073,P24539,P14854,P25705,P03886 | Processes and pathways | KEGG Pathways | msigdb_kegg | 2,521,4,397,14,514,146,281,659,412,656,288,40,579,560,558,449,461,727,352,223,232,108,109,484,501,500 | 656,2858,1367,4,3021,2587,514,2369,1435,710,793,2,1514,3175,2060,1515,558,500,40,223,1663,1664,108,560,484,14,3211,3142,659,3023,3076,2332,232,109,501,2886,2483,1473,281,1137,1791,1713,521,3124,397,3294,412,1637,3321,2730,146,1180,2635,352,461,2931,579,1622,727,288,449 | 0.6933477721843095,-0.8190021137923701,0.15034720133396523,4.551842722059264,-0.9834347839005033,-0.5908507122210328,0.8693977289284917,-0.4654184907728244,0.10738556209941592,0.6276115039211269,0.5620305844376072,5.167196520160504,0.06449608277835585,-1.2074277428722162,-0.2759883981888322,0.06449608277835585,0.803251... | 3,430 |
Parkinsons disease | 24 | 55 | 2.998876 | 0.00271 | P48047,O43676,P51970,P14927,O75306,Q16718,P36542,P20674,P42574,P12235,P06576,Q9UDW1,P14406,P00403,Q9Y6M9,P45880,P08574,P22695,P13073,P24539,P14854,P25705,P03886,P21796 | Processes and pathways | KEGG Pathways | msigdb_kegg | 521,4,397,14,514,146,281,659,533,406,40,579,560,558,449,603,223,232,108,109,484,501,500,249 | 656,2858,1367,4,3021,2587,514,2369,1435,710,793,1514,3175,2060,1515,558,500,2331,40,223,1663,1664,406,1811,108,560,484,14,3211,3142,659,249,2332,1333,232,109,501,2886,2483,1473,281,533,603,1713,521,3124,397,1405,1599,146,1180,3329,579,2549,449 | 0.6933477721843095,-0.8190021137923701,0.15034720133396523,4.551842722059264,-0.9834347839005033,-0.5908507122210328,0.8693977289284917,-0.4654184907728244,0.10738556209941592,0.6276115039211269,0.5620305844376072,0.06449608277835585,-1.2074277428722162,-0.2759883981888322,0.06449608277835585,0.8032512025014997,0.89148... | 3,430 |
centrosome | 16 | 36 | 2.977871 | 0.002903 | P06493,Q04917,O43237,P62258,Q9NSK0,P27348,Q9BZD4,Q9BV73,P33176,P31946,P41208,Q10713,P61981,P0DP25,P63104,Q13561 | Localization | OpenCell Localization | opencell_localization | 543,284,311,67,402,677,596,309,110,178,19,414,427,338,316,415 | 311,1287,1045,3039,543,338,1632,1879,677,178,110,2234,19,1714,2485,427,67,316,284,1341,414,1406,910,415,1526,833,696,2384,1822,2955,2504,309,596,1120,402,1067 | 1.2024003828056788,0.19338072765197223,0.3662283341069291,-1.0038990229805613,0.8252830651235218,1.1577834161963467,-0.02106529204966477,-0.17009375816547115,0.6714184729428473,1.6748229295823038,2.0165882176348306,-0.38141593935161383,3.204350628748325,-0.06373662902854216,-0.5282207546911941,1.0021471184507622,2.4313... | 3,430 |
Cellular response to heat | 10 | 33 | 2.95515 | 0.003125 | O15514,Q58FF6,P62258,Q9H078,P09601,Q13535,O95391,P42345,P12270,P07900 | Processes and pathways | GO Biological process | msigdb_gobp | 163,196,67,333,71,292,70,233,107,314 | 163,1289,1462,70,1235,1707,314,404,71,1073,107,1632,1879,2973,1168,233,2138,882,67,661,292,1410,196,2458,3018,3085,629,1765,333,2222,2913,1621,1734 | 1.742891610000047,0.19338072765197223,0.0859317852989234,2.40815588672373,0.23648587072936555,-0.06373662902854216,1.2024003828056788,1.0243308327237213,2.40815588672373,0.34456029993080256,2.0394981091593998,-0.02106529204966477,-0.17009375816547115,-0.9219218352181526,0.2796623627116229,1.4264710812485106,-0.31821572... | 3,430 |
Muscle contraction | 10 | 30 | 2.952398 | 0.003153 | P09493,Q13177,P08670,Q05682,P06753,P67936,P18206,P04083,Q99996,Q9NYL9 | Processes and pathways | Reactome Pathways | msigdb_reactome | 3,195,11,204,176,16,393,583,387,611 | 1660,583,1261,176,822,1465,11,3,602,1632,1879,393,852,1919,1843,3301,2437,2275,743,16,204,2709,195,2071,2280,2177,387,2325,611,1362 | -0.04241010240522003,0.7812363588966038,0.21492436389411237,1.6748229295823038,0.5402049440683143,0.0859317852989234,3.824533083456319,4.649741438376801,0.7592385640896675,-0.02106529204966477,-0.17009375816547115,1.0465312750378557,0.518396688704323,-0.191309831206804,-0.14885918591010985,-1.5685621747527327,-0.507305... | 3,430 |
Sensory processing of sound by outer hair cells of the cochlea | 6 | 14 | 2.952383 | 0.003153 | Q01082,Q6IBS0,P26038,P15311,Q13813,P35241 | Processes and pathways | Reactome Pathways | msigdb_reactome | 256,143,90,87,119,25 | 1948,1126,87,1919,90,25,444,2109,256,1342,119,1445,143,842 | -0.21250736851480986,0.3012772815040069,2.177283285595381,-0.191309831206804,2.131292988821414,3.0861951345931513,0.9799801607699364,-0.2971114238181862,1.359078200582899,0.17185499556109507,1.9708151956500113,0.10738556209941592,1.8338719570141517,0.5402049440683143 | 3,430 |
membrane traffic protein | 27 | 66 | 2.949869 | 0.003179 | Q5JRA6,Q9BRG1,P43307,Q8IUD2,O43747,Q9NX40,Q8WUX9,Q96PC5,Q08379,P51572,Q96A65,P54920,Q9UK41,O60645,O60763,P50570,P49257,Q5VIR6,Q9H223,Q9H4M9,Q96RL7,O00429,Q9UBC2,Q9UPT5,Q96QK1,O60313,A6NIH7 | Functions | Panther Protein class | panther_protein_class | 525,529,132,134,636,422,537,29,155,410,307,302,580,423,312,194,562,722,73,344,610,600,632,113,507,616,127 | 127,1874,600,2023,636,616,423,312,1547,1290,1915,3374,2747,1881,1266,714,2630,132,939,562,194,410,302,3417,1207,1580,2678,155,859,1084,2174,996,525,722,1855,134,2661,537,1310,307,1421,1311,29,507,610,2911,1827,1729,529,836,73,867,1937,344,1063,422,1121,3049,1323,632,1867,580,113,2055,1870,2720 | 1.9251046821425566,-0.17009375816547115,0.7592385640896675,-0.254846688969337,0.7152942406319166,0.7372578479891295,1.0021471184507622,1.2024003828056788,0.04307848903912287,0.19338072765197223,-0.191309831206804,-2.0004675616234437,-0.7155893800863863,-0.17009375816547115,0.21492436389411237,0.6276115039211269,-0.6116... | 3,430 |
Protein insertion into membrane | 8 | 29 | 2.928455 | 0.003407 | Q15006,Q9NS69,Q9P0J0,O14737,Q96A33,Q9Y5L4,Q9Y5J9,P07900 | Processes and pathways | GO Biological process | msigdb_gobp | 189,7,45,206,238,114,84,314 | 206,766,1231,987,314,1667,1746,879,3302,995,189,589,1558,2634,2415,1249,1604,2118,238,705,7,403,45,1590,819,843,1774,84,114 | 1.5165554046538223,0.5838735785783277,0.23648587072936555,0.4096172898409424,1.2024003828056788,-0.04241010240522003,-0.08504483643208101,0.4966058497171867,-1.5685621747527327,0.4096172898409424,1.6068977874861423,0.7812363588966038,0.04307848903912287,-0.6116888886017858,-0.4863716580376144,0.23648587072936555,0.0002... | 3,430 |
Intermediate filament | 9 | 21 | 2.913795 | 0.003571 | Q03252,P58107,P08670,P20700,P02545,Q16352,P07197,Q15149,Q9UPN3 | Localization | GO Cellular component | msigdb_gocc | 34,485,11,77,46,82,55,416,321 | 2623,46,900,55,11,2885,1957,77,1440,545,1714,3201,485,2240,34,416,82,950,1832,1571,321 | -0.6116888886017858,2.6872054940154664,0.4748324586170831,2.5706715559059043,3.824533083456319,-0.8396256696385406,-0.21250736851480986,2.3156233598343645,0.10738556209941592,0.8252830651235218,-0.06373662902854216,-1.2680873203022425,0.9135801145844248,-0.38141593935161383,2.8979047777720357,1.0243308327237213,2.22333... | 3,430 |
Mitochondrial protein import | 17 | 36 | 2.911949 | 0.003592 | Q9Y512,P12235,P08574,Q9NS69,Q8N4H5,P06576,Q9HAV7,Q99595,Q13505,Q9Y5L4,Q9Y5J9,Q10713,Q9NX63,O60830,P25705,O75431,P21796 | Processes and pathways | Reactome Pathways | msigdb_reactome | 819,406,223,7,546,40,760,703,588,114,84,414,578,56,501,219,249 | 2585,1546,56,2431,219,2300,1985,987,3130,40,223,901,406,1811,249,501,1814,1524,414,588,2754,1967,1684,546,703,2981,760,7,578,2546,1590,819,843,1774,84,114 | -0.5908507122210328,0.04307848903912287,2.547409768053795,-0.5073057591164345,1.4714808810674698,-0.4234551139739826,-0.23368633339360326,0.4096172898409424,-1.1262605148954412,2.8041124444238252,1.448967877539575,0.4748324586170831,1.0243308327237213,-0.12760615078476442,1.3815262161857498,0.8914804711800896,-0.127606... | 3,430 |
Primary mitochondrial disease | 37 | 97 | 2.889384 | 0.00386 | O43676,Q6DKK2,P14927,O75306,Q9NWS8,P20674,O00217,P12235,Q99797,Q9P0J0,Q5T2R2,Q9Y2R0,Q00059,Q9UBX3,P00403,Q8N183,Q9Y6M9,O75489,Q9NPL8,P03886,Q07021,Q70HW3,Q9BQT8,P52815,Q86Y39,P82650,P08574,P22695,Q9BW92,P13073,P14854,P09001,Q7L0Y3,P82930,O60313,P25705,Q8NI60 | Drugs and Diseases | Protein Atlas Disease involvement | protein_atlas_disease_involvement | 4,267,14,514,18,659,656,406,438,45,305,49,50,320,558,68,449,710,476,500,217,754,93,91,352,349,223,232,362,108,484,735,628,505,616,501,252 | 656,2858,1367,4,3021,2025,616,2587,514,2369,710,1513,1234,2060,2770,558,500,1841,223,735,406,108,484,14,3142,659,232,501,2886,2483,1138,739,2889,1713,2375,3124,91,2521,349,505,50,217,1180,2634,1052,998,2951,305,2712,2755,267,1490,754,2635,628,3336,352,2536,68,1758,252,1058,2287,1280,1092,2007,1763,923,2389,438,2982,149... | 0.6933477721843095,-0.8190021137923701,0.15034720133396523,4.551842722059264,-0.9834347839005033,-0.254846688969337,0.7372578479891295,-0.5908507122210328,0.8693977289284917,-0.4654184907728244,0.6276115039211269,0.06449608277835585,0.23648587072936555,-0.2759883981888322,-0.736311113618571,0.8032512025014997,0.8914804... | 3,430 |
Sensory processing of sound | 7 | 19 | 2.886997 | 0.003889 | Q13813,Q01082,Q6IBS0,P52907,P15311,P35241,P26038 | Processes and pathways | Reactome Pathways | msigdb_reactome | 119,256,143,301,87,25,90 | 1948,1126,87,852,1919,90,25,444,991,1672,301,3009,2109,256,1342,119,1445,143,842 | -0.21250736851480986,0.3012772815040069,2.177283285595381,0.518396688704323,-0.191309831206804,2.131292988821414,3.0861951345931513,0.9799801607699364,0.4096172898409424,-0.04241010240522003,1.2247336356763627,-0.9629504767360699,-0.2971114238181862,1.359078200582899,0.17185499556109507,1.9708151956500113,0.10738556209... | 3,430 |
Negative regulation of protein polymerization | 12 | 30 | 2.871532 | 0.004085 | Q13813,Q15691,Q01082,P45880,O15020,P16949,Q9NUQ9,Q6IBS0,Q02790,P52907,P35241,Q9NYL9 | Processes and pathways | GO Biological process | msigdb_gobp | 119,696,256,603,634,8,630,143,368,301,25,611 | 634,709,1626,1132,3210,8,1843,2799,25,1670,2272,603,991,1672,301,2562,256,368,1598,2204,119,2381,696,143,2312,1424,1313,630,611,1196 | 0.7152942406319166,0.6276115039211269,-0.02106529204966477,0.3012772815040069,-1.2882658134684348,4.186646783930239,-0.14885918591010985,-0.7570132956764223,3.0861951345931513,-0.04241010240522003,-0.40244498209708657,0.7592385640896675,0.4096172898409424,-0.04241010240522003,1.2247336356763627,-0.569993271061387,1.359... | 3,430 |
Structural constituent of cytoskeleton | 7 | 35 | 2.855188 | 0.004301 | P09493,P08670,Q9Y5K6,Q16352,P07197,Q13813,P26038 | Functions | GO Molecular function | msigdb_gomf | 3,11,247,82,55,119,90 | 531,634,1511,2367,3255,1132,900,55,988,11,3,2404,1957,90,2272,972,3010,1848,2139,256,2491,119,1581,1445,416,1179,82,1585,3002,1220,2083,1196,842,1362,247 | 0.8473319171085857,0.7152942406319166,0.06449608277835585,-0.4654184907728244,-1.4088990437313549,0.3012772815040069,0.4748324586170831,2.5706715559059043,0.4096172898409424,3.824533083456319,4.649741438376801,-0.4863716580376144,-0.21250736851480986,2.131292988821414,-0.40244498209708657,0.43133814681776855,-0.9629504... | 3,430 |
Programmed cell death | 39 | 99 | 2.844747 | 0.004445 | O75955,O43242,Q9UNM6,P08670,Q9Y3B8,Q92530,Q8WUX9,Q15149,P42574,Q04917,O00560,P51572,Q9NR28,P28070,P02545,P31946,P61981,P62191,P63104,Q13464,P48556,P07900,Q13177,P62258,Q9Y5V3,P17980,P49354,P20700,Q16543,Q07021,Q15008,P61289,P62195,Q14254,P09429,O00429,O00231,P26583,Q13813 | Processes and pathways | Reactome Pathways | msigdb_reactome | 377,375,269,11,278,538,537,416,533,284,154,410,552,41,46,178,427,184,316,430,445,314,195,67,599,454,203,77,340,217,470,213,214,221,465,600,356,621,119 | 356,2699,1573,600,1777,154,897,1979,375,616,2401,377,46,2302,3341,314,11,465,3400,1957,3372,3368,454,1990,77,1992,902,2233,2434,621,677,1169,737,41,2199,3025,1439,1667,178,2829,1670,1790,2168,533,798,445,1553,203,2304,2065,410,940,3241,2377,1882,1635,213,427,184,214,67,2239,316,2991,284,1598,1026,217,2201,995,2175,195,... | 1.1132326864910351,-0.6740874247602239,0.02167903874393584,0.7592385640896675,-0.10633468895957496,1.7656129496664057,0.4748324586170831,-0.23368633339360326,1.0687484169607406,0.7372578479891295,-0.4863716580376144,1.0687484169607406,2.6872054940154664,-0.4234551139739826,-1.7465394682740971,1.2024003828056788,3.82453... | 3,430 |
Translation factor | 10 | 27 | 2.826396 | 0.004708 | P23588,Q14152,Q15056,O75153,P60228,P29692,O75822,P24534,Q86TB9,P78344 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 96,257,329,66,262,75,270,299,251,283 | 1950,2551,2059,66,270,1707,1016,1133,96,299,75,2889,1239,2708,3201,262,1142,413,283,1299,2112,257,568,329,1347,251,894 | -0.21250736851480986,-0.569993271061387,-0.2759883981888322,2.431327036159296,1.291832142745204,-0.06373662902854216,0.387914008197925,0.3012772815040069,2.108321019317115,1.2247336356763627,2.361859163920826,-0.8396256696385406,0.23648587072936555,-0.6740874247602239,-1.2680873203022425,1.3366464985559088,0.3012772815... | 3,430 |
Nadh dehydrogenase complex assembly | 12 | 28 | 2.814947 | 0.004879 | Q9Y6M9,Q8N183,O43676,Q9H061,P51970,Q9P0J0,O75306,Q16718,Q15070,P03886,Q86Y39,O00217 | Processes and pathways | GO Biological process | msigdb_gobp | 449,68,4,39,397,45,514,146,589,500,352,656 | 656,4,3021,2587,514,1435,710,1514,2060,1515,500,2886,397,589,146,1180,1821,352,68,1058,1092,3101,39,1191,813,45,1590,449 | 0.6933477721843095,4.551842722059264,-0.9834347839005033,-0.5908507122210328,0.8693977289284917,0.10738556209941592,0.6276115039211269,0.06449608277835585,-0.2759883981888322,0.06449608277835585,0.8914804711800896,-0.8396256696385406,1.0465312750378557,0.7812363588966038,1.8111031480459492,0.2796623627116229,-0.1276061... | 3,430 |
Centriolar satellite | 11 | 35 | 2.81313 | 0.004906 | Q9Y448,P33176,O95613,Q8WXW3,O43809,Q9Y5K6,P41208,O43169,Q86UY6,Q9P260,Q15907 | Localization | Protein Atlas Subcellular | protein_atlas_subcellular_location_all | 172,110,515,371,513,247,19,115,22,319,159 | 1574,115,2969,513,1101,1013,515,3178,110,19,2109,994,2173,1799,2204,2450,1484,696,159,1602,1491,886,22,3117,2000,371,1971,319,553,172,1362,1737,2093,247,2022 | 0.02167903874393584,1.993693905134758,-0.9219218352181526,0.8693977289284917,0.3229099381780773,0.387914008197925,0.8693977289284917,-1.2074277428722162,2.0165882176348306,3.204350628748325,-0.2971114238181862,0.4096172898409424,-0.3393012744587857,-0.10633468895957496,-0.36036802408587215,-0.5073057591164345,0.0859317... | 3,430 |
Oxidative phosphorylation | 27 | 61 | 2.758422 | 0.005808 | O75964,P48047,O43676,P51970,P14927,O75306,Q16718,P36542,P20674,Q96QE5,P14635,Q9BSK2,P06493,P56385,P06576,Q9UDW1,P14406,P00403,Q9Y6M9,O75323,P08574,P22695,P13073,P24539,Q9UJZ1,P25705,P03886 | Processes and pathways | GO Biological process | msigdb_gobp | 2,521,4,397,14,514,146,281,659,286,658,287,543,412,40,579,560,558,449,464,223,232,108,109,390,501,500 | 656,2858,1367,4,3021,2587,514,464,2369,1435,710,793,2,1514,3175,2060,1515,558,500,543,40,223,2268,1664,108,560,658,14,3211,3142,659,232,109,501,1203,2886,3059,2483,1473,1136,281,768,1713,521,3124,397,882,3294,412,744,146,1180,2417,2635,286,3329,287,3414,579,390,449 | 0.6933477721843095,-0.8190021137923701,0.15034720133396523,4.551842722059264,-0.9834347839005033,-0.5908507122210328,0.8693977289284917,0.9356966299859146,-0.4654184907728244,0.10738556209941592,0.6276115039211269,0.5620305844376072,5.167196520160504,0.06449608277835585,-1.2074277428722162,-0.2759883981888322,0.0644960... | 3,430 |
Proton transmembrane transporter activity | 17 | 35 | 2.75472 | 0.005874 | P00403,O75964,P48047,Q93050,P12235,O95202,P08574,P56385,P06576,P13073,P24539,P14854,Q9UDW1,P36542,P25705,P20674,Q9Y5K8 | Functions | GO Molecular function | msigdb_gomf | 558,2,521,461,406,638,223,412,40,108,109,484,579,281,501,659,288 | 793,2,638,558,2331,40,223,1664,406,108,484,659,3023,3076,109,501,1473,281,1137,1791,1713,521,3294,412,1637,2488,884,2635,461,3160,2814,579,1622,727,288 | 0.5620305844376072,5.167196520160504,0.7152942406319166,0.8032512025014997,-0.44444629644309747,2.8041124444238252,1.448967877539575,-0.04241010240522003,1.0243308327237213,2.0394981091593998,0.9135801145844248,0.6933477721843095,-0.9834347839005033,-1.0447671183808418,2.0394981091593998,0.8914804711800896,0.0859317852... | 3,430 |
Calcium-binding protein | 8 | 21 | 2.752096 | 0.005922 | P43307,Q99584,Q14257,O43852,P41208,P0DP25,Q9BRK5,P80303 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 132,42,236,48,19,338,23,62 | 48,338,3293,1371,19,132,743,2411,62,2832,236,457,2714,1350,1529,1563,3019,42,1729,23,818 | 2.6638687791403814,1.1577834161963467,-1.548678875208257,0.15034720133396523,3.204350628748325,1.8794568708577217,0.6057338953933035,-0.4863716580376144,2.4545133476558236,-0.7776958844485033,1.4264710812485106,0.9578299883515244,-0.6740874247602239,0.17185499556109507,0.06449608277835585,0.04307848903912287,-0.9629504... | 3,430 |
Intermediate filament cytoskeleton | 11 | 37 | 2.739188 | 0.006159 | Q03252,Q99471,P58107,P08670,P20700,P02545,Q9UNZ2,Q16352,P07197,Q15149,Q9UPN3 | Localization | GO Cellular component | msigdb_gocc | 34,436,485,11,77,46,441,82,55,416,321 | 2623,2401,46,900,55,11,2885,1957,77,1440,545,1714,1403,1845,3201,485,2240,34,2950,416,82,1447,1147,3083,2418,1930,1149,436,950,1832,2223,1732,1942,1571,761,441,321 | -0.6116888886017858,-0.4863716580376144,2.6872054940154664,0.4748324586170831,2.5706715559059043,3.824533083456319,-0.8396256696385406,-0.21250736851480986,2.3156233598343645,0.10738556209941592,0.8252830651235218,-0.06373662902854216,0.12885737883854684,-0.14885918591010985,-1.2680873203022425,0.9135801145844248,-0.38... | 3,430 |
Inorganic molecular entity transmembrane transporter activity | 34 | 71 | 2.733631 | 0.006264 | Q13423,O75964,P48047,O95202,Q6P4Q7,O43681,Q9C0H2,P36542,P20674,P56385,Q9Y5K8,P12235,Q99797,P06576,O75947,Q9UDW1,Q9UBX3,Q93034,P00403,Q93050,P07355,Q9Y487,P55011,Q9HD20,P45880,P20020,P08574,P16615,P13073,P24539,P14854,Q9Y6M7,P25705,P21796 | Functions | GO Molecular function | msigdb_gomf | 884,2,521,638,399,766,150,281,659,412,288,406,438,40,793,579,320,58,558,461,822,727,829,227,603,852,223,602,108,109,484,896,501,249 | 2622,766,793,2,638,558,1261,2331,40,3176,822,1465,1916,223,1395,1664,406,108,484,602,852,659,3023,3076,249,1919,109,501,1473,281,1137,1791,603,1713,521,2274,829,3294,412,1637,3302,2488,1639,1242,884,2413,913,3421,399,2635,1056,1419,58,461,3160,1004,438,2014,150,1936,2814,227,320,579,1622,1324,2549,727,288,2857,896 | -0.6116888886017858,0.5838735785783277,0.5620305844376072,5.167196520160504,0.7152942406319166,0.8032512025014997,0.21492436389411237,-0.44444629644309747,2.8041124444238252,-1.2074277428722162,0.5402049440683143,0.0859317852989234,-0.191309831206804,1.448967877539575,0.12885737883854684,-0.04241010240522003,1.02433083... | 3,430 |
Respiratory chain | 13 | 33 | 2.712881 | 0.00667 | Q9Y6M9,O43676,P08574,P51970,P22695,Q6DKK2,Q9P0J0,P14927,O75306,Q9UDW1,Q16718,P03886,Q86Y39 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 449,4,223,397,232,267,45,14,514,579,146,500,352 | 656,2858,1367,4,3021,2587,514,2369,1435,710,1514,3175,2060,1515,558,500,223,14,3142,232,2886,1473,1713,3124,397,146,1180,267,352,1092,45,579,449 | 0.6933477721843095,-0.8190021137923701,0.15034720133396523,4.551842722059264,-0.9834347839005033,-0.5908507122210328,0.8693977289284917,-0.4654184907728244,0.10738556209941592,0.6276115039211269,0.06449608277835585,-1.2074277428722162,-0.2759883981888322,0.06449608277835585,0.8032512025014997,0.8914804711800896,1.44896... | 3,430 |
Sensory perception | 8 | 29 | 2.71165 | 0.006695 | Q13813,Q01082,P49354,Q6IBS0,P52907,P15311,P35241,P26038 | Processes and pathways | Reactome Pathways | msigdb_reactome | 119,256,203,143,301,87,25,90 | 1948,1126,87,1632,852,1919,90,1786,1667,25,444,991,1672,203,740,3078,301,3009,2307,2109,256,2923,1342,119,1445,143,2283,2420,842 | -0.21250736851480986,0.3012772815040069,2.177283285595381,-0.02106529204966477,0.518396688704323,-0.191309831206804,2.131292988821414,-0.10633468895957496,-0.04241010240522003,3.0861951345931513,0.9799801607699364,0.4096172898409424,-0.04241010240522003,1.5391168723820783,0.6057338953933035,-1.0447671183808418,1.224733... | 3,430 |
ATPase, AAA-type, core [IPR003959] | 16 | 30 | 2.652859 | 0.007981 | Q9H078,Q9UN37,P40937,P17980,Q8WVB6,P43686,P36776,Q5T9A4,Q9Y4W6,Q15645,P62191,P55072,P62195,Q96TA2,Q9NVI7,P46459 | Sequence | InterPro Domain | interpro_domain | 333,980,241,454,237,798,395,317,895,650,184,882,214,187,354,939 | 1594,1984,986,454,2436,2800,1294,1790,395,241,798,939,882,184,214,2239,650,317,2756,2001,1492,237,1971,187,1973,333,354,980,1590,895 | 0.0002977667180233936,-0.23368633339360326,0.4096172898409424,0.9578299883515244,-0.5073057591164345,-0.7570132956764223,0.19338072765197223,-0.10633468895957496,1.0465312750378557,1.4039905186201218,0.5620305844376072,0.45307654705381356,0.4966058497171867,1.65216523300499,1.4940100655111697,-0.38141593935161383,0.715... | 3,430 |
Translation initiation factor | 8 | 21 | 2.594312 | 0.009478 | P23588,Q14152,Q15056,O75153,P60228,O75822,Q86TB9,P78344 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 96,257,329,66,262,270,251,283 | 1950,2551,2059,66,270,1707,1016,1133,96,1239,2708,3201,262,413,283,1299,2112,257,329,251,894 | -0.21250736851480986,-0.569993271061387,-0.2759883981888322,2.431327036159296,1.291832142745204,-0.06373662902854216,0.387914008197925,0.3012772815040069,2.108321019317115,0.23648587072936555,-0.6740874247602239,-1.2680873203022425,1.3366464985559088,1.0243308327237213,1.269449542990556,0.19338072765197223,-0.297111423... | 3,430 |
Alzheimers disease | 22 | 62 | 2.593419 | 0.009503 | P48047,O43676,P51970,P14927,O75306,Q16718,P36542,P20674,P42574,P06576,Q9UDW1,P14406,P00403,Q9Y6M9,P0DP25,P16615,P08574,P22695,P13073,P24539,P14854,P25705 | Processes and pathways | KEGG Pathways | msigdb_kegg | 521,4,397,14,514,146,281,659,533,40,579,560,558,449,338,602,223,232,108,109,484,501 | 3360,656,2858,1367,4,3021,2587,514,2369,1435,710,793,1514,3175,2060,1515,558,2402,2099,40,1955,223,1663,338,1664,108,560,796,484,14,3211,602,2655,3142,659,2332,232,109,501,1169,2886,1439,2483,1473,281,533,1713,521,1553,3124,397,1882,1639,2923,942,146,1180,2048,2961,579,1621,449 | -1.844649948742758,0.6933477721843095,-0.8190021137923701,0.15034720133396523,4.551842722059264,-0.9834347839005033,-0.5908507122210328,0.8693977289284917,-0.4654184907728244,0.10738556209941592,0.6276115039211269,0.5620305844376072,0.06449608277835585,-1.2074277428722162,-0.2759883981888322,0.06449608277835585,0.80325... | 3,430 |
Proton transporting two sector atpase complex | 9 | 22 | 2.591461 | 0.009557 | O75964,Q93050,P06576,P56385,P24539,P36542,P25705,Q8N511,Q9Y5K8 | Localization | GO Cellular component | msigdb_gocc | 2,461,40,412,109,281,501,57,288 | 793,2,40,3023,3076,109,501,281,1137,1791,521,3294,412,1637,2730,57,461,1763,2122,1622,727,288 | 0.5620305844376072,5.167196520160504,2.8041124444238252,-0.9834347839005033,-1.0447671183808418,2.0394981091593998,0.8914804711800896,1.269449542990556,0.3012772815040069,-0.10633468895957496,0.8693977289284917,-1.548678875208257,1.0243308327237213,-0.02106529204966477,-0.6948481366740377,2.547409768053795,0.9578299883... | 3,430 |
Apoptotic cleavage of cellular proteins | 8 | 20 | 2.582875 | 0.009798 | P51572,Q13813,P08670,P49354,P20700,P02545,Q13464,Q15149 | Processes and pathways | Reactome Pathways | msigdb_reactome | 410,119,11,203,77,46,430,416 | 46,11,1957,77,2829,1670,533,203,410,1882,1598,2201,430,119,2993,416,721,2877,2468,2192 | 2.6872054940154664,3.824533083456319,-0.21250736851480986,2.3156233598343645,-0.7776958844485033,-0.04241010240522003,0.8473319171085857,1.5391168723820783,1.0243308327237213,-0.17009375816547115,0.0002977667180233936,-0.36036802408587215,1.0021471184507622,1.9708151956500113,-0.942446145812876,1.0243308327237213,0.627... | 3,430 |
Spectrin/alpha-actinin [IPR018159] | 8 | 13 | 2.578027 | 0.009937 | Q01082,O43707,O75962,P46939,Q9UPN3,Q13813,Q15149,P12814 | Sequence | InterPro Repeat | interpro_repeat | 256,289,106,425,321,119,416,466 | 634,289,106,466,1957,2437,425,256,2240,119,416,1149,321 | 0.7152942406319166,1.2470833648713042,2.0394981091593998,0.9356966299859146,-0.21250736851480986,-0.5073057591164345,1.0021471184507622,1.359078200582899,-0.38141593935161383,1.9708151956500113,1.0243308327237213,0.3012772815040069,1.2024003828056788 | 3,430 |
Intra golgi traffic | 8 | 15 | 2.576127 | 0.009991 | Q13190,P83436,Q96MW5,P54920,O60476,Q9NRW7,O00461,Q8TBA6 | Processes and pathways | Reactome Pathways | msigdb_reactome | 165,428,447,302,51,419,153,63 | 153,876,51,1130,3054,939,302,428,165,1086,63,447,1827,419,581 | 1.7656129496664057,0.4966058497171867,2.6172401968299104,0.3012772815040069,-1.024343149410197,0.45307654705381356,1.2247336356763627,1.0021471184507622,1.742891610000047,0.34456029993080256,2.4545133476558236,0.9799801607699364,-0.12760615078476442,1.0243308327237213,0.8032512025014997 | 3,430 |
calmodulin-related | 7 | 14 | 2.575834 | 0.01 | Q99584,Q14257,O43852,P41208,P0DP25,Q9BRK5,P80303 | Functions | Panther Protein class | panther_protein_class | 42,236,48,19,338,23,62 | 48,338,3301,1371,19,2411,62,2832,236,457,1529,3019,42,23 | 2.6638687791403814,1.1577834161963467,-1.5685621747527327,0.15034720133396523,3.204350628748325,-0.4863716580376144,2.4545133476558236,-0.7776958844485033,1.4264710812485106,0.9578299883515244,0.06449608277835585,-0.9629504767360699,2.8041124444238252,3.109797184993122 | 3,430 |
Negative regulation of supramolecular fiber organization | 19 | 54 | 2.559316 | 0.010488 | Q01082,O15020,P16949,O15212,Q6IBS0,P35241,Q99471,Q13136,P52907,Q15691,Q13177,Q9UHV9,O75146,Q92974,Q9NYL9,Q9NUQ9,Q9UBN7,Q02790,Q13813 | Processes and pathways | GO Biological process | msigdb_gobp | 256,634,8,12,143,25,436,52,301,696,195,598,709,92,611,630,246,368,119 | 634,12,1574,1983,709,1626,1132,3210,1165,8,1843,2799,25,1670,2272,2438,991,1672,301,2562,2069,2991,256,368,1598,2201,2204,52,195,119,2381,696,143,2312,755,1822,2418,2955,92,2787,436,1424,3281,1313,2323,630,2465,611,246,1196,1620,598,2668,2915 | 0.7152942406319166,3.6087693640312484,0.02167903874393584,-0.23368633339360326,0.6276115039211269,-0.02106529204966477,0.3012772815040069,-1.2882658134684348,0.2796623627116229,4.186646783930239,-0.14885918591010985,-0.7570132956764223,3.0861951345931513,-0.04241010240522003,-0.40244498209708657,-0.5073057591164345,0.4... | 3,430 |
Respirasome | 19 | 45 | 2.556625 | 0.010569 | O43676,P51970,Q6DKK2,P14927,O75306,Q16718,P20674,O00217,Q9P0J0,Q9UDW1,P14406,P00403,Q9Y6M9,Q86Y39,P08574,P22695,P13073,P14854,P03886 | Localization | GO Cellular component | msigdb_gocc | 4,397,267,14,514,146,659,656,45,579,560,558,449,352,223,232,108,484,500 | 656,2858,1367,4,3021,2587,514,2369,1435,710,1514,3175,2060,1515,558,500,223,1663,1664,108,560,484,14,3211,3142,659,2332,232,2886,2483,1473,1713,3124,397,884,146,1180,267,2635,352,1092,45,579,1590,449 | 0.6933477721843095,-0.8190021137923701,0.15034720133396523,4.551842722059264,-0.9834347839005033,-0.5908507122210328,0.8693977289284917,-0.4654184907728244,0.10738556209941592,0.6276115039211269,0.06449608277835585,-1.2074277428722162,-0.2759883981888322,0.06449608277835585,0.8032512025014997,0.8914804711800896,1.44896... | 3,430 |
Establishment of protein localization to membrane | 20 | 89 | 2.555055 | 0.010617 | Q01082,Q9NS69,P43307,Q8IWJ2,Q15041,O15118,Q15907,O00560,Q9P0J0,Q9UPN3,P07900,Q15006,O14737,Q9Y5J9,O60725,P0DP25,Q9HD20,Q96A33,Q13277,Q9Y5L4 | Processes and pathways | GO Biological process | msigdb_gobp | 256,7,132,263,266,265,159,154,45,321,314,189,206,84,86,338,227,238,111,114 | 1948,1874,154,206,2821,265,766,1231,86,2096,557,987,1436,314,1988,338,2166,1667,2519,1746,2593,714,1711,132,879,939,2776,691,2409,1796,3417,2103,2104,1579,3302,1884,1639,256,995,2491,1342,111,2679,189,266,1345,589,1558,2730,159,2344,2634,2415,1249,3117,263,2000,1604,1492,3000,2118,238,507,2124,1861,551,2932,2693,227,70... | -0.21250736851480986,-0.17009375816547115,1.7656129496664057,1.5165554046538223,-0.7776958844485033,1.314231136956651,0.5838735785783277,0.23648587072936555,2.177283285595381,-0.2971114238181862,0.8032512025014997,0.4096172898409424,0.10738556209941592,1.2024003828056788,-0.23368633339360326,1.1577834161963467,-0.33930... | 3,430 |
Apoptosis | 33 | 90 | 2.554916 | 0.010621 | O43242,Q9UNM6,P08670,Q9Y3B8,Q92530,Q15149,P42574,Q04917,P51572,Q9NR28,P28070,P02545,P31946,P61981,P62191,P63104,Q13464,P48556,Q13177,P62258,Q9Y5V3,P17980,P49354,P20700,Q07021,Q15008,P61289,P62195,P09429,O00429,O00231,P26583,Q13813 | Processes and pathways | Reactome Pathways | msigdb_reactome | 375,269,11,278,538,416,533,284,410,552,41,46,178,427,184,316,430,445,195,67,599,454,203,77,217,470,213,214,465,600,356,621,119 | 356,2699,1573,600,1777,897,375,616,2401,46,2302,3341,11,465,3400,1957,3372,3368,454,1990,77,1992,902,2233,2434,621,677,1169,737,41,2199,3025,1439,1667,178,2829,1670,1790,2168,533,798,445,1553,203,2304,2065,410,940,3241,2377,1882,1635,213,427,184,214,67,2239,316,2991,284,1598,1026,217,2201,995,2175,195,772,430,1176,119,... | 1.1132326864910351,-0.6740874247602239,0.02167903874393584,0.7592385640896675,-0.10633468895957496,0.4748324586170831,1.0687484169607406,0.7372578479891295,-0.4863716580376144,2.6872054940154664,-0.4234551139739826,-1.7465394682740971,3.824533083456319,0.9356966299859146,-2.6088832120872674,-0.21250736851480986,-1.9810... | 3,430 |
Response to heat | 11 | 44 | 2.551294 | 0.010732 | O15514,Q58FF6,P62258,Q9H078,P09601,Q13535,O95391,P42345,P12270,P49770,P07900 | Processes and pathways | GO Biological process | msigdb_gobp | 163,196,67,333,71,292,70,233,107,367,314 | 163,1625,1289,1462,2432,70,1235,1707,314,404,71,1073,107,1632,1879,2973,1168,1669,233,1295,367,2138,680,882,67,1114,661,292,1212,1410,196,2458,3018,3085,2424,629,1765,333,2222,2506,2913,1621,2226,1734 | 1.742891610000047,-0.02106529204966477,0.19338072765197223,0.0859317852989234,-0.5073057591164345,2.40815588672373,0.23648587072936555,-0.06373662902854216,1.2024003828056788,1.0243308327237213,2.40815588672373,0.34456029993080256,2.0394981091593998,-0.02106529204966477,-0.17009375816547115,-0.9219218352181526,0.279662... | 3,430 |
Myometrial relaxation and contraction pathways | 11 | 26 | 2.527157 | 0.011499 | Q04917,P16615,P62258,Q05682,Q9Y3B8,P31946,P61981,P05771,P0DP25,O43665,P63104 | Processes and pathways | WikiPathways | msigdb_wp | 284,602,67,204,278,178,427,584,338,54,316 | 54,584,338,1236,1074,602,877,1632,1879,2061,677,178,2828,427,67,2307,316,1444,1269,284,1598,204,2071,2280,3304,278 | 2.5706715559059043,0.7812363588966038,1.1577834161963467,0.23648587072936555,0.34456029993080256,0.7592385640896675,0.4966058497171867,-0.02106529204966477,-0.17009375816547115,-0.2759883981888322,0.6714184729428473,1.6748229295823038,-0.7776958844485033,1.0021471184507622,2.431327036159296,-0.4234551139739826,1.202400... | 3,430 |
Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand | 20 | 31 | 2.521609 | 0.011682 | P61163,Q13451,Q9Y6G9,Q13561,P11142,P25685,P08238,P54652,P31948,Q15185,P52907,O75935,Q14203,P07900,Q14204,O43237,P0DMV9,P04350,P47755,Q02790 | Processes and pathways | Reactome Pathways | msigdb_reactome | 1141,398,1067,415,1165,1168,404,680,290,943,301,443,188,314,833,311,1073,1132,991,368 | 311,1625,443,1132,314,404,1073,1165,1168,1669,290,991,1672,301,680,1141,2991,2139,368,1406,398,415,1581,188,833,943,1220,2083,2360,2091,1067 | 1.2024003828056788,-0.02106529204966477,0.9799801607699364,0.3012772815040069,1.2024003828056788,1.0243308327237213,0.34456029993080256,0.2796623627116229,0.2796623627116229,-0.04241010240522003,1.2470833648713042,0.4096172898409424,-0.04241010240522003,1.2247336356763627,0.6714184729428473,0.3012772815040069,-0.942446... | 3,430 |
Cristae formation | 10 | 19 | 2.521508 | 0.011685 | O75964,P48047,P06576,Q16891,P24539,Q9NX63,P36542,P25705,O75431,P56385 | Processes and pathways | Reactome Pathways | msigdb_reactome | 2,521,40,360,109,578,281,501,219,412 | 219,793,2,40,109,501,281,1814,521,3294,412,588,360,2755,1999,3129,1319,578,819 | 1.4714808810674698,0.5620305844376072,5.167196520160504,2.8041124444238252,2.0394981091593998,0.8914804711800896,1.269449542990556,-0.12760615078476442,0.8693977289284917,-1.548678875208257,1.0243308327237213,0.7812363588966038,1.1132326864910351,-0.7155893800863863,-0.23368633339360326,-1.1059176287710073,0.1933807276... | 3,430 |
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