term
stringlengths 2
121
| overlap
int64 6
281
| setsize
int64 7
499
| score
float64 1.96
10.6
| pval
float64 0
0.05
| edge
stringlengths 41
1.97k
| type
stringclasses 5
values | subtype
stringclasses 24
values | subtype_key
stringclasses 24
values | edge_idxs
stringlengths 11
1.17k
| ann_idxs
stringlengths 19
2.31k
| ann_vals
stringlengths 124
9.94k
| sig_size
int64 2.2k
3.73k
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Micromelia
| 8
| 24
| 2.064087
| 0.039009
|
P48735,Q15392,Q96HY6,Q9UHX1,O43175,Q14739,Q9UBM7,O75874
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
129,34,294,8,232,50,154,286
|
744,3218,232,2725,2044,2630,361,286,516,589,129,1591,537,1777,50,34,2175,2297,294,1909,154,8,1097,3355
|
0.38894919874105743,-1.0027041076562464,1.400546940102355,-0.5995724062727221,-0.28358176189719153,-0.5503155785430718,0.9592374039290533,1.1924031585962547,0.6556730905320322,0.5452985658990057,1.9852909461843653,-0.09381103021537567,0.6336831437767028,-0.16457479426822091,3.1189087835415297,3.583187167896173,-0.33156716576876,-0.3797760297676727,1.171392087430195,-0.2120155691768394,1.826640669391119,5.057543677692156,0.16172434863187643,-1.369914466388914
| 3,430
|
Organic acid transmembrane transport
| 8
| 29
| 2.060106
| 0.039388
|
P08183,Q9BQT8,O43772,P23786,Q9H2D1,Q9Y619,Q9UBX3,O14678
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
323,486,109,270,151,57,189,466
|
466,109,2935,699,1985,1520,856,323,1988,1338,270,1192,504,2642,2218,2381,1657,1247,964,1121,773,827,486,151,1903,1326,189,977,57
|
0.7432157338415764,2.1420351304999743,-0.7237852836123975,0.4338422448747199,-0.25967184066824295,-0.07032759590587762,0.2986183093020084,1.0445510616836513,-0.25967184066824295,0.02309332399172761,1.2552190861703458,0.09263033605246422,0.6776210718932071,-0.5503155785430718,-0.35564345936189407,-0.42821167915506675,-0.11734646334023954,0.06950099771551356,0.23038416792428346,0.1387416835614649,0.38894919874105743,0.3438753282799643,0.7213921450541884,1.8465787199040886,-0.2120155691768394,0.04632210615831087,1.6255321690560474,0.23038416792428346,2.8994929547828066
| 3,430
|
Disproportionate short limb short stature
| 11
| 24
| 2.043628
| 0.04099
|
Q96MF7,Q15392,P42345,Q7LGA3,Q9UBN7,Q14739,O75718,Q32P28,Q6DKJ4,P10644,Q9UBM7
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
290,34,482,171,500,50,361,247,117,589,154
|
1183,606,3218,2630,361,589,3244,482,1864,1118,1664,1828,50,34,247,117,171,2297,2610,290,1909,154,500,1467
|
0.09263033605246422,0.5230949161824157,-1.0027041076562464,-0.5503155785430718,0.9592374039290533,0.5452985658990057,-1.0542934068429035,0.7213921450541884,-0.2120155691768394,0.1387416835614649,-0.11734646334023954,-0.18826843715602568,3.1189087835415297,3.583187167896173,1.338473936006947,2.083474851760708,1.7063569746264826,-0.3797760297676727,-0.5257770590663371,1.1924031585962547,-0.2120155691768394,1.826640669391119,0.6995273401513898,-0.02351528122041195
| 3,430
|
Slender long bone
| 7
| 15
| 2.042707
| 0.041081
|
Q96MF7,Q96J02,P37268,Q32P28,Q96L58,Q9Y487,Q9Y619
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
290,295,385,247,215,24,57
|
516,2161,385,2341,247,2958,1962,295,215,290,1323,1047,1620,24,57
|
0.6556730905320322,-0.33156716576876,0.9163495326117879,-0.4039652952055236,1.338473936006947,-0.7237852836123975,-0.23581657417804916,1.171392087430195,1.4828295622266432,1.1924031585962547,0.04632210615831087,0.18465877239643577,-0.09381103021537567,4.186254663337337,2.8994929547828066
| 3,430
|
Intrinsic component of mitochondrial inner membrane
| 19
| 30
| 2.042379
| 0.041114
|
Q8NE86,Q5XKP0,Q16891,Q9Y512,Q6P4A7,Q99595,Q9NVH1,Q9NX63,Q96NB2,Q13505,Q6UXV4,Q9Y2R0,Q16134,Q15070,O60830,O43819,Q9H9P8,O14925,O75880
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
899,896,405,546,277,157,829,298,827,596,844,81,224,350,97,360,777,122,752
|
122,360,97,1335,752,1520,2643,2908,1350,596,350,224,405,1305,896,277,844,899,827,157,2661,3394,1326,777,829,298,2307,81,948,546
|
2.0442894948035293,0.9592374039290533,2.3161817108012213,0.02309332399172761,0.38894919874105743,-0.07032759590587762,-0.5503155785430718,-0.6988183969795223,0.02309332399172761,0.5452985658990057,0.9806232501634713,1.4417564181063023,0.8733052663722602,0.04632210615831087,0.2759203789757193,1.2343164607296082,0.32126985958171844,0.2759203789757193,0.3438753282799643,1.8066716660719826,-0.5503155785430718,-1.9788713010588765,0.04632210615831087,0.38894919874105743,0.3438753282799643,1.1503444701717498,-0.3797760297676727,2.5638146678084146,0.25317576686812393,0.6336831437767028
| 3,430
|
Abnormal arterial physiology
| 7
| 30
| 2.040948
| 0.041256
|
Q9NWM8,Q9NZ08,O75844,P01889,P05067,Q14739,P06280
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
137,299,139,329,46,50,156
|
1573,434,1576,550,2937,139,329,954,2680,46,156,2161,2904,2482,1705,2828,1653,2165,1530,1660,1533,50,707,2011,2014,137,299,2089,1229,657
|
-0.09381103021537567,0.8084416390325024,-0.09381103021537567,0.6116509767559337,-0.7237852836123975,1.9260244005596443,1.0232798624432902,0.23038416792428346,-0.5749138732638202,3.191306028311356,1.8066716660719826,-0.33156716576876,-0.6988183969795223,-0.4768775233718424,-0.1409342612489813,-0.6490720698046804,-0.11734646334023954,-0.33156716576876,-0.07032759590587762,-0.11734646334023954,-0.07032759590587762,3.1189087835415297,0.4338422448747199,-0.25967184066824295,-0.25967184066824295,1.9458099313348363,1.1503444701717498,-0.28358176189719153,0.09263033605246422,0.5008477318133796
| 3,430
|
Phagocytic vesicle membrane
| 7
| 23
| 2.034641
| 0.041887
|
Q15907,Q03518,P01889,Q93050,P04439,Q9Y487,P13473
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
389,74,329,45,335,24,217
|
985,1577,329,335,402,611,632,217,2904,1027,2057,1115,2538,2386,2167,921,74,1073,389,45,1322,2974,24
|
0.20754527371745304,-0.09381103021537567,1.0232798624432902,1.0019706637911983,0.8733052663722602,0.5230949161824157,0.5008477318133796,1.4623099427802935,-0.6988183969795223,0.18465877239643577,-0.28358176189719153,0.1387416835614649,-0.5012978577516536,-0.42821167915506675,-0.33156716576876,0.25317576686812393,2.620328163937606,0.16172434863187643,0.9163495326117879,3.2093487244594585,0.04632210615831087,-0.7237852836123975,4.186254663337337
| 3,430
|
Retinal detachment
| 7
| 16
| 2.033645
| 0.041987
|
Q96MF7,Q99496,Q8NAT1,O43505,P04439,O75533,Q9H9S5
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
290,559,273,146,335,588,283
|
146,588,335,1705,1653,634,1533,922,1664,273,290,559,283,1626,1465,1693
|
1.866485968870282,0.5452985658990057,1.0019706637911983,-0.1409342612489813,-0.11734646334023954,0.5008477318133796,-0.07032759590587762,0.25317576686812393,-0.11734646334023954,1.2552190861703458,1.1924031585962547,0.6116509767559337,1.213377883648462,-0.09381103021537567,-0.02351528122041195,-0.11734646334023954
| 3,430
|
Hyperlipidemia
| 10
| 30
| 2.033368
| 0.042015
|
Q96MF7,P49257,Q92734,O43707,P50402,O75844,P23786,P28070,O95470,P06280
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
290,263,523,479,396,139,270,80,147,156
|
1853,479,1335,139,147,954,156,1583,1765,270,80,955,1389,3391,263,396,2218,2874,922,1664,1947,1258,557,523,1962,290,1794,977,1053,2931
|
-0.2120155691768394,0.7213921450541884,0.02309332399172761,1.9260244005596443,1.866485968870282,0.23038416792428346,1.8066716660719826,-0.09381103021537567,-0.16457479426822091,1.2552190861703458,2.5638146678084146,0.23038416792428346,-0.00018569005958125493,-1.9788713010588765,1.2760859545124026,0.8948470616767685,-0.35564345936189407,-0.6739141572295496,0.25317576686812393,-0.11734646334023954,-0.23581657417804916,0.06950099771551356,0.6116509767559337,0.6556730905320322,-0.23581657417804916,1.1924031585962547,-0.16457479426822091,0.23038416792428346,0.18465877239643577,-0.6988183969795223
| 3,430
|
Nuclear inner membrane
| 7
| 23
| 2.029637
| 0.042393
|
O76062,O75844,P50402,Q99720,Q14739,Q8IXM6,Q9H1E5
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
69,139,396,47,50,242,279
|
139,69,628,564,1863,858,396,2387,1071,441,1663,866,50,1884,2124,242,3211,1791,47,1794,279,1416,2254
|
1.9260244005596443,2.714006070492743,0.5008477318133796,0.5895763319810627,-0.2120155691768394,0.2986183093020084,0.8948470616767685,-0.42821167915506675,0.16172434863187643,0.8084416390325024,-0.11734646334023954,0.2986183093020084,3.1189087835415297,-0.2120155691768394,-0.30754673593761184,1.359199686384635,-0.977013463993979,-0.16457479426822091,3.173240775887535,-0.16457479426822091,1.2343164607296082,-0.00018569005958125493,-0.35564345936189407
| 3,430
|
Hallucinations
| 9
| 48
| 2.027078
| 0.042654
|
O00754,P07602,P50897,O75503,P35637,P05067,Q9BQE5,O60313,Q6DKK2
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
66,36,6,138,140,46,19,94,31
|
3343,915,66,811,94,1186,138,812,2678,213,46,36,2820,2323,730,2161,2437,2579,1586,2787,140,1068,412,1428,1026,2908,6,2832,1656,2166,2221,1944,2067,2391,3184,31,1205,2128,367,2460,3127,3393,19,1274,652,977,2197,2368
|
-1.3431986759033332,0.25317576686812393,2.8070566341243905,0.3438753282799643,2.35457505060863,0.09263033605246422,1.9260244005596443,0.3438753282799643,-0.5749138732638202,1.4828295622266432,3.191306028311356,3.495034957042614,-0.6490720698046804,-0.4039652952055236,0.4114181815276483,-0.33156716576876,-0.4525156104496164,-0.5257770590663371,-0.09381103021537567,-0.6242916466860307,1.9260244005596443,0.16172434863187643,0.8517239183017473,-0.02351528122041195,0.18465877239643577,-0.6988183969795223,5.121449989369716,-0.6490720698046804,-0.11734646334023954,-0.33156716576876,-0.35564345936189407,-0.23581657417804916,-0.28358176189719153,-0.42821167915506675,-0.9258372702304992,3.7926560390546924,0.09263033605246422,-0.30754673593761184,0.9592374039290533,-0.4525156104496164,-0.849577203134417,-1.9788713010588765,4.3877182006716735,0.06950099771551356,0.5008477318133796,0.23038416792428346,-0.33156716576876,-0.4039652952055236
| 3,430
|
Signaling
| 6
| 20
| 2.02303
| 0.04307
|
O15173,P43490,Q8WUJ1,P17931,O00264,Q96PC5
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
344,11,76,301,239,193
|
239,344,2320,301,1391,11,1865,617,1248,2917,705,792,379,1206,76,1895,739,193,1615,2421
|
1.359199686384635,0.9806232501634713,-0.4039652952055236,1.1292601049826305,-0.00018569005958125493,4.864332563034109,-0.2120155691768394,0.5230949161824157,0.06950099771551356,-0.6988183969795223,0.4338422448747199,0.36643501064183787,0.937812905361756,0.09263033605246422,2.601516115344004,-0.2120155691768394,0.4114181815276483,1.6052450348577447,-0.09381103021537567,-0.42821167915506675
| 3,430
|
Regulation of endothelial cell migration
| 7
| 30
| 2.015566
| 0.043845
|
P57105,P42785,Q8WTV0,P09429,P04083,P09601,Q9H6U6
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
227,38,71,363,83,20,419
|
1573,1232,1753,2523,660,83,1383,491,1758,363,20,632,2051,2160,2270,2824,1587,3111,2904,38,2793,227,2833,2446,1593,2393,71,1791,419,1414
|
-0.09381103021537567,0.06950099771551356,-0.16457479426822091,-0.5012978577516536,0.4785567416325205,2.5260093370892096,-0.00018569005958125493,0.6995273401513898,-0.16457479426822091,0.9592374039290533,4.337593478683959,0.5008477318133796,-0.28358176189719153,-0.33156716576876,-0.3797760297676727,-0.6490720698046804,-0.09381103021537567,-0.849577203134417,-0.6988183969795223,3.441890793303961,-0.6242916466860307,1.4211688103555455,-0.6490720698046804,-0.4525156104496164,-0.09381103021537567,-0.42821167915506675,2.6953211040640213,-0.16457479426822091,0.8517239183017473,-0.00018569005958125493
| 3,430
|
Mitochondrial membrane organization
| 16
| 50
| 2.013402
| 0.044072
|
Q9Y584,Q15070,Q9Y5J9,P0DP25,O95202,O14737,Q9NX63,O94826,Q16891,Q9P0J0,Q9Y5L4,Q9NS69,P45880,Q9UII2,Q9Y5Z4,O60313
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
96,350,225,324,383,70,298,233,405,211,183,23,26,222,322,94
|
809,70,94,1334,1335,233,383,2680,2049,661,1932,324,631,2737,2687,2944,2643,2644,26,1113,2792,1817,1297,617,596,350,405,1538,1305,896,844,714,1168,643,1083,2661,3394,23,829,298,211,222,2197,948,546,96,421,225,183,322
|
0.3438753282799643,2.6953211040640213,2.35457505060863,0.02309332399172761,0.02309332399172761,1.400546940102355,0.9163495326117879,-0.5749138732638202,-0.28358176189719153,0.4785567416325205,-0.23581657417804916,1.0445510616836513,0.5008477318133796,-0.5995724062727221,-0.5749138732638202,-0.7237852836123975,-0.5503155785430718,-0.5503155785430718,4.1354813465701925,0.1387416835614649,-0.6242916466860307,-0.18826843715602568,0.04632210615831087,0.5230949161824157,0.5452985658990057,0.9806232501634713,0.8733052663722602,-0.07032759590587762,0.04632210615831087,0.2759203789757193,0.32126985958171844,0.4338422448747199,0.1157104547340278,0.5008477318133796,0.16172434863187643,-0.5503155785430718,-1.9788713010588765,4.236863344428605,0.3438753282799643,1.1503444701717498,1.5033154527373318,1.4623099427802935,-0.33156716576876,0.25317576686812393,0.6336831437767028,2.3353920752424693,0.8517239183017473,1.4417564181063023,1.6457867663301875,1.0657844750365362
| 3,430
|
Mitochondrial fusion
| 10
| 14
| 2.012271
| 0.044191
|
Q9NQG6,P02786,Q9UJZ1,Q9NX63,Q8N2A8,Q8TB36,Q8NAN2,Q8IWA4,Q07812,O60313
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
259,728,697,298,427,368,51,714,617,94
|
94,728,617,1607,714,427,51,368,1793,259,298,697,948,834
|
2.35457505060863,0.4114181815276483,0.5230949161824157,-0.09381103021537567,0.4338422448747199,0.8301027868261046,3.1189087835415297,0.9592374039290533,-0.16457479426822091,1.296917258531428,1.1503444701717498,0.45622167162433763,0.25317576686812393,0.3438753282799643
| 3,430
|
Lysosomal transport
| 9
| 44
| 2.011724
| 0.044249
|
Q14108,P07602,O15118,Q9Y2T2,P11717,Q99523,Q96L92,P13473,Q9UNK0
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
130,36,164,106,330,78,188,217,260
|
809,2153,359,2315,164,1803,1285,1754,36,1584,611,330,217,1237,1296,2057,1115,2166,681,130,2174,2882,2701,684,933,2408,1732,188,3127,78,1044,1140,1221,1738,2358,652,1375,1178,1799,1279,1627,979,260,106
|
0.3438753282799643,-0.33156716576876,0.9592374039290533,-0.4039652952055236,1.7465774077703615,-0.18826843715602568,0.04632210615831087,-0.16457479426822091,3.495034957042614,-0.09381103021537567,0.5230949161824157,1.0232798624432902,1.4623099427802935,0.06950099771551356,0.04632210615831087,-0.28358176189719153,0.1387416835614649,-0.33156716576876,0.45622167162433763,1.9852909461843653,-0.33156716576876,-0.6739141572295496,-0.5749138732638202,0.45622167162433763,0.25317576686812393,-0.42821167915506675,-0.1409342612489813,1.6255321690560474,-0.849577203134417,2.5826783205648556,0.18465877239643577,0.1387416835614649,0.09263033605246422,-0.1409342612489813,-0.4039652952055236,0.5008477318133796,0.02309332399172761,0.1157104547340278,-0.16457479426822091,0.06950099771551356,-0.09381103021537567,0.23038416792428346,1.296917258531428,2.2197146760906703
| 3,430
|
Regulation of blood pressure
| 6
| 19
| 2.006216
| 0.044833
|
P42785,P09493,Q9UIQ6,Q9HB40,P42892,P09601
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
38,201,12,17,49,20
|
3352,1423,201,20,3160,503,38,49,2792,2793,2833,3237,999,793,1048,17,299,12,574
|
-1.369914466388914,-0.02351528122041195,1.5645724906173264,4.337593478683959,-0.900350577456945,0.6776210718932071,3.441890793303961,3.1189087835415297,-0.6242916466860307,-0.6242916466860307,-0.6490720698046804,-1.0284638912585382,0.20754527371745304,0.36643501064183787,0.18465877239643577,4.454305506671291,1.1503444701717498,4.766868416503872,0.5895763319810627
| 3,430
|
Abnormal thoracic spine morphology
| 7
| 31
| 2.000499
| 0.045446
|
O00754,Q96J02,Q9UHX1,O75844,P08236,P04062,P51648
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
66,295,8,139,246,213,223
|
1573,982,66,2627,952,2630,587,139,1421,1930,954,213,813,246,758,1760,2580,3235,1817,223,1533,2499,2957,3212,1732,2555,2610,295,873,400,8
|
-0.09381103021537567,0.20754527371745304,2.8070566341243905,-0.5503155785430718,0.23038416792428346,-0.5503155785430718,0.5452985658990057,1.9260244005596443,-0.02351528122041195,-0.23581657417804916,0.23038416792428346,1.4828295622266432,0.3438753282799643,1.338473936006947,0.38894919874105743,-0.16457479426822091,-0.5257770590663371,-1.0284638912585382,-0.18826843715602568,1.4417564181063023,-0.07032759590587762,-0.4768775233718424,-0.7237852836123975,-0.977013463993979,-0.1409342612489813,-0.5012978577516536,-0.5257770590663371,1.171392087430195,0.2986183093020084,0.8948470616767685,5.057543677692156
| 3,430
|
Platyspondyly
| 13
| 35
| 1.998242
| 0.04569
|
P48735,O00754,Q96HY6,Q9UBN7,Q14739,P08236,Q32P28,Q96AY3,P16278,Q96L58,Q6NUK1,Q6NUQ1,O75874
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
129,66,294,500,50,246,247,448,179,215,472,258,286
|
2624,66,3218,952,550,2630,286,2431,1930,1422,246,179,2980,3244,2440,1862,129,1591,995,921,1533,50,2957,247,792,472,258,1494,448,2610,294,215,2715,500,2309
|
-0.5503155785430718,2.8070566341243905,-1.0027041076562464,0.23038416792428346,0.6116509767559337,-0.5503155785430718,1.1924031585962547,-0.4525156104496164,-0.23581657417804916,-0.02351528122041195,1.338473936006947,1.6457867663301875,-0.7488153183487716,-1.0542934068429035,-0.4525156104496164,-0.2120155691768394,1.9852909461843653,-0.09381103021537567,0.20754527371745304,0.25317576686812393,-0.07032759590587762,3.1189087835415297,-0.7237852836123975,1.338473936006947,0.36643501064183787,0.7432157338415764,1.296917258531428,-0.04689579872958434,0.8084416390325024,-0.5257770590663371,1.171392087430195,1.4828295622266432,-0.5749138732638202,0.6995273401513898,-0.3797760297676727
| 3,430
|
Ventricular arrhythmia
| 11
| 43
| 1.99733
| 0.045789
|
P0DP25,P46976,P09493,P50402,O43772,P23786,P03886,P10253,P42892,O75306,P13473
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
324,331,201,396,109,270,15,144,49,309,217
|
109,2572,309,1637,394,954,15,755,1642,2820,201,324,144,631,217,2051,1856,2437,1763,270,1706,1068,2871,49,331,2114,2908,396,1299,2745,1947,894,1719,1038,1450,557,2608,1732,1134,623,1045,1794,3213
|
2.1420351304999743,-0.5257770590663371,1.0869803140135814,-0.11734646334023954,0.8948470616767685,0.23038416792428346,4.652417670407559,0.38894919874105743,-0.11734646334023954,-0.6490720698046804,1.5645724906173264,1.0445510616836513,1.8863625663085712,0.5008477318133796,1.4623099427802935,-0.28358176189719153,-0.2120155691768394,-0.4525156104496164,-0.16457479426822091,1.2552190861703458,-0.1409342612489813,0.16172434863187643,-0.6739141572295496,3.1189087835415297,1.0232798624432902,-0.30754673593761184,-0.6988183969795223,0.8948470616767685,0.04632210615831087,-0.5995724062727221,-0.23581657417804916,0.2759203789757193,-0.1409342612489813,0.18465877239643577,-0.02351528122041195,0.6116509767559337,-0.5257770590663371,-0.1409342612489813,0.1387416835614649,0.5230949161824157,0.18465877239643577,-0.16457479426822091,-0.977013463993979
| 3,430
|
Abnormal delivery
| 7
| 22
| 1.996593
| 0.045869
|
O75844,Q6YHK3,O75718,Q9Y487,Q9UBM7,O60313,Q9Y619
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
139,463,361,24,154,94,57
|
1853,94,361,139,3220,954,813,2161,2326,1591,1027,483,1533,463,1833,3211,1501,1458,2087,154,24,57
|
-0.2120155691768394,2.35457505060863,0.9592374039290533,1.9260244005596443,-1.0027041076562464,0.23038416792428346,0.3438753282799643,-0.33156716576876,-0.4039652952055236,-0.09381103021537567,0.18465877239643577,0.7213921450541884,-0.07032759590587762,0.7649983512811526,-0.18826843715602568,-0.977013463993979,-0.04689579872958434,-0.02351528122041195,-0.28358176189719153,1.826640669391119,4.186254663337337,2.8994929547828066
| 3,430
|
Ascites
| 9
| 29
| 1.994534
| 0.046094
|
Q14108,P61916,P63241,O15118,Q14739,P08236,P04062,Q13510,Q01844
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
130,256,347,164,50,246,213,313,124
|
164,786,2261,1472,2781,213,246,589,788,2822,2271,3391,2165,1941,256,347,593,1394,124,1662,1713,313,130,50,1829,381,2145,1909,3048
|
1.7465774077703615,0.36643501064183787,-0.3797760297676727,-0.04689579872958434,-0.6242916466860307,1.4828295622266432,1.338473936006947,0.5452985658990057,0.36643501064183787,-0.6490720698046804,-0.3797760297676727,-1.9788713010588765,-0.33156716576876,-0.23581657417804916,1.296917258531428,0.9806232501634713,0.5452985658990057,-0.00018569005958125493,2.0246528531620718,-0.11734646334023954,-0.1409342612489813,1.0869803140135814,1.9852909461843653,3.1189087835415297,-0.18826843715602568,0.937812905361756,-0.30754673593761184,-0.2120155691768394,-0.7739090091989397
| 3,430
|
Telangiectasia
| 8
| 38
| 1.99259
| 0.046306
|
Q13535,P03886,Q8IZA0,Q14739,O75306,O95453,P10619,P06280
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
348,15,272,50,309,119,25,156
|
1805,2861,309,953,119,954,15,156,2434,25,2375,2324,758,1760,2824,1763,955,1705,3247,1814,2444,1866,537,1713,1250,1664,348,50,2174,2014,272,739,2559,381,2611,2142,3008,2420
|
-0.18826843715602568,-0.6739141572295496,1.0869803140135814,0.23038416792428346,2.063896781548296,0.23038416792428346,4.652417670407559,1.8066716660719826,-0.4525156104496164,4.1354813465701925,-0.42821167915506675,-0.4039652952055236,0.38894919874105743,-0.16457479426822091,-0.6490720698046804,-0.16457479426822091,0.23038416792428346,-0.1409342612489813,-1.0542934068429035,-0.18826843715602568,-0.4525156104496164,-0.2120155691768394,0.6336831437767028,-0.1409342612489813,0.06950099771551356,-0.11734646334023954,0.9806232501634713,3.1189087835415297,-0.33156716576876,-0.25967184066824295,1.2552190861703458,0.4114181815276483,-0.5012978577516536,0.937812905361756,-0.5257770590663371,-0.30754673593761184,-0.7488153183487716,-0.42821167915506675
| 3,430
|
Severe short stature
| 7
| 24
| 1.980543
| 0.047643
|
Q96MF7,Q15392,P16278,Q96L58,P53701,Q9Y619,P10619
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
290,34,179,215,276,57,25
|
3218,2897,2630,25,179,1763,2440,2583,1862,2643,994,634,276,840,537,34,2958,3170,1501,294,215,290,1323,57
|
-1.0027041076562464,-0.6988183969795223,-0.5503155785430718,4.1354813465701925,1.6457867663301875,-0.16457479426822091,-0.4525156104496164,-0.5257770590663371,-0.2120155691768394,-0.5503155785430718,0.20754527371745304,0.5008477318133796,1.2343164607296082,0.32126985958171844,0.6336831437767028,3.583187167896173,-0.7237852836123975,-0.900350577456945,-0.04689579872958434,1.171392087430195,1.4828295622266432,1.1924031585962547,0.04632210615831087,2.8994929547828066
| 3,430
|
Azurophil granule membrane
| 7
| 22
| 1.976785
| 0.048066
|
P07602,P42785,Q07065,P10253,O15260,Q9NQX7,P13473
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
36,38,113,144,149,220,217
|
149,2629,3157,1186,36,144,611,217,2112,38,2163,1115,113,1078,1729,341,3282,3171,1010,220,652,1973
|
1.8465787199040886,-0.5503155785430718,-0.900350577456945,0.09263033605246422,3.495034957042614,1.8863625663085712,0.5230949161824157,1.4623099427802935,-0.30754673593761184,3.441890793303961,-0.33156716576876,0.1387416835614649,2.122543890584666,0.16172434863187643,-0.1409342612489813,1.0019706637911983,-1.1061640452367623,-0.900350577456945,0.20754527371745304,1.4623099427802935,0.5008477318133796,-0.23581657417804916
| 3,430
|
Protein localization to mitochondrion
| 21
| 59
| 1.973948
| 0.048388
|
O43615,P49257,Q9NS69,P55786,Q9Y5J7,Q99595,Q9Y5L4,P0DP25,O14737,Q99797,Q9P0J0,Q9UII2,Q8N4H5,Q9Y584,Q15070,Q9Y5J9,O60830,O94826,Q8TB36,O14925,Q5JRX3
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
134,263,23,152,421,157,183,324,70,199,211,222,95,96,350,225,97,233,368,122,126
|
2773,809,915,70,122,134,97,1578,233,2631,1289,1700,1930,2678,661,324,3085,435,2376,3142,2687,1194,1810,2944,263,2792,2380,1297,152,2914,617,1157,350,820,2802,1538,1305,126,1607,95,368,1083,559,157,199,649,1412,23,211,3290,222,2197,3284,546,96,421,225,183,834
|
-0.6242916466860307,0.3438753282799643,0.25317576686812393,2.6953211040640213,2.0442894948035293,1.965565398534416,2.3161817108012213,-0.09381103021537567,1.400546940102355,-0.5503155785430718,0.04632210615831087,-0.1409342612489813,-0.23581657417804916,-0.5749138732638202,0.4785567416325205,1.0445510616836513,-0.8242894260138783,0.8084416390325024,-0.42821167915506675,-0.8749307389569164,-0.5749138732638202,0.09263033605246422,-0.18826843715602568,-0.7237852836123975,1.2760859545124026,-0.6242916466860307,-0.42821167915506675,0.04632210615831087,1.826640669391119,-0.6988183969795223,0.5230949161824157,0.1157104547340278,0.9806232501634713,0.3438753282799643,-0.6242916466860307,-0.07032759590587762,0.04632210615831087,2.0049867171526095,-0.09381103021537567,2.35457505060863,0.9592374039290533,0.16172434863187643,0.6116509767559337,1.8066716660719826,1.5849251978248329,0.5008477318133796,-0.00018569005958125493,4.236863344428605,1.5033154527373318,-1.1322063957742325,1.4623099427802935,-0.33156716576876,-1.1061640452367623,0.6336831437767028,2.3353920752424693,0.8517239183017473,1.4417564181063023,1.6457867663301875,0.3438753282799643
| 3,430
|
Muscle abnormality related to mitochondrial dysfunction
| 10
| 37
| 1.97344
| 0.048446
|
O43676,Q96CU9,Q9Y6M9,P14854,P00403,P03886,Q9Y2R0,O75306,Q9UBX3,O60313
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
35,103,373,424,394,15,81,309,189,94
|
698,2257,35,94,2104,309,1697,1920,1062,3219,610,394,15,631,424,2578,2736,1863,3196,2116,1305,474,898,2182,1893,103,1134,2891,2469,2764,875,721,189,81,2721,1570,373
|
0.4338422448747199,-0.3797760297676727,3.512707326927762,2.35457505060863,-0.30754673593761184,1.0869803140135814,-0.1409342612489813,-0.23581657417804916,0.16172434863187643,-1.0027041076562464,0.5230949161824157,0.8948470616767685,4.652417670407559,0.5008477318133796,0.8301027868261046,-0.5257770590663371,-0.5995724062727221,-0.2120155691768394,-0.9513913766449668,-0.30754673593761184,0.04632210615831087,0.7432157338415764,0.2759203789757193,-0.33156716576876,-0.2120155691768394,2.239063866307495,0.1387416835614649,-0.6739141572295496,-0.4525156104496164,-0.5995724062727221,0.2986183093020084,0.4338422448747199,1.6255321690560474,2.5638146678084146,-0.5749138732638202,-0.07032759590587762,0.9592374039290533
| 3,430
|
Hexosyltransferase activity
| 12
| 36
| 1.968081
| 0.049059
|
Q6ZXV5,P06865,Q2TAA5,P46976,Q13126,Q8NAT1,O43505,O60512,P04062,Q96L58,Q8N4A0,Q10472
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
289,99,556,331,205,273,146,150,213,215,281,469
|
2624,1982,146,952,150,550,1805,2523,213,917,1384,1583,99,918,2159,1645,1389,331,1815,1533,1662,732,469,205,556,289,1126,281,273,1263,1673,215,941,1970,3416,782
|
-0.5503155785430718,-0.25967184066824295,1.866485968870282,0.23038416792428346,1.8465787199040886,0.6116509767559337,-0.18826843715602568,-0.5012978577516536,1.4828295622266432,0.25317576686812393,-0.00018569005958125493,-0.09381103021537567,2.277678317409277,0.25317576686812393,-0.33156716576876,-0.11734646334023954,-0.00018569005958125493,1.0232798624432902,-0.18826843715602568,-0.07032759590587762,-0.11734646334023954,0.4114181815276483,0.7432157338415764,1.5441867444483162,0.6116509767559337,1.1924031585962547,0.1387416835614649,1.213377883648462,1.2552190861703458,0.06950099771551356,-0.11734646334023954,1.4828295622266432,0.25317576686812393,-0.23581657417804916,-2.697856726640414,0.38894919874105743
| 3,430
|
Metatarsus adductus
| 6
| 13
| 1.960521
| 0.049935
|
O96028,Q15392,O95202,P08236,Q96L58,Q9UBM7
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
191,34,383,246,215,154
|
383,191,246,1650,1817,441,1869,2797,34,215,1047,154,2974
|
0.9163495326117879,1.6052450348577447,1.338473936006947,-0.11734646334023954,-0.18826843715602568,0.8084416390325024,-0.2120155691768394,-0.6242916466860307,3.583187167896173,1.4828295622266432,0.18465877239643577,1.826640669391119,-0.7237852836123975
| 3,430
|
Lumenal side of endoplasmic reticulum membrane
| 6
| 8
| 2.484994
| 0.012955
|
Q8TCT9,P04439,P01889,P27824,P51572,P10321
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
70,168,269,270,340,158
|
343,269,168,158,1352,270,340,70
|
1.0364629614668819,1.2630600632743048,1.6610108338836194,1.757884300742988,0.06407338100523642,1.2630600632743048,1.057305181951178,2.553352994479783
| 3,430
|
Antigen processing and presentation of endogenous peptide antigen
| 7
| 9
| 2.462907
| 0.013782
|
Q03519,Q6P179,P04439,P01889,Q03518,Q9NZ08,P10321
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
129,293,168,269,112,24,158
|
343,269,168,158,1677,112,129,293,24
|
1.0364629614668819,1.2630600632743048,1.6610108338836194,1.757884300742988,-0.10213768578822673,2.061430403594576,1.891865759389253,1.1813305049758258,3.553979031490054
| 3,430
|
Antigen processing and presentation of endogenous antigen
| 7
| 9
| 2.462907
| 0.013782
|
Q03519,Q6P179,P04439,P01889,Q03518,Q9NZ08,P10321
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
129,293,168,269,112,24,158
|
343,269,168,158,1677,112,129,293,24
|
1.0364629614668819,1.2630600632743048,1.6610108338836194,1.757884300742988,-0.10213768578822673,2.061430403594576,1.891865759389253,1.1813305049758258,3.553979031490054
| 3,430
|
Antiporter activity
| 6
| 8
| 2.253867
| 0.024205
|
P12236,P05141,Q02978,P12235,Q9UBX3,P08195
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
320,357,396,319,92,287
|
392,357,287,319,320,2352,396,92
|
0.9314960696962661,1.015570844477996,1.2018332759105956,1.0988413665209409,1.0988413665209409,-0.3959200417834923,0.9314960696962661,2.283047194513152
| 3,430
|
Porphyrin and chlorophyll metabolism
| 7
| 14
| 2.172429
| 0.029823
|
P36551,P30519,P09601,P22830,Q5JPH6,P08236,Q96EY8
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
99,5,101,11,240,205,310
|
1111,1350,205,2295,101,11,5,99,2188,1357,306,240,1056,310
|
0.20374464368210365,0.06407338100523642,1.503894702163965,-0.3709853125137018,2.172859102163878,4.107772994111282,5.03017478838894,2.2097242428181456,-0.32137042377466907,0.06407338100523642,1.1401822218335855,1.3641854583979733,0.24975397691551138,1.1401822218335855
| 3,430
|
Mhc protein binding
| 7
| 11
| 2.131278
| 0.033066
|
P06576,Q03519,Q03518,P51572,O15533,Q9NUQ9,P25705
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
225,129,112,340,343,28,254
|
343,225,1479,254,340,624,2249,112,129,377,28
|
1.0364629614668819,1.4043211024190974,-0.006717839319282361,1.3036465389571528,1.057305181951178,0.5866553931117515,-0.34613573151426974,2.061430403594576,1.891865759389253,0.973635461621998,3.407140852160664
| 3,430
|
Mhc class i protein binding
| 6
| 10
| 2.05678
| 0.039707
|
P06576,Q03519,Q03518,P51572,O15533,P25705
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
225,129,112,340,343,254
|
343,225,1479,254,340,624,2249,112,129,377
|
1.0364629614668819,1.4043211024190974,-0.006717839319282361,1.3036465389571528,1.057305181951178,0.5866553931117515,-0.34613573151426974,2.061430403594576,1.891865759389253,0.973635461621998
| 3,430
|
Tetrapyrrole binding
| 11
| 18
| 2.052407
| 0.04013
|
P30519,P09601,O43169,Q16850,O15173,Q8WUJ1,P08574,O00264,Q96EY8,P53701,Q6UW02
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
5,101,38,170,141,44,143,146,310,306,97
|
146,141,38,143,101,304,5,306,170,97,1056,44,310,1516,480,855,2473,2064
|
1.8155355874645718,1.8537767842690276,3.208299500767211,1.83467532885005,2.172859102163878,1.1401822218335855,5.03017478838894,1.1401822218335855,1.6610108338836194,2.2464531018578775,0.24975397691551138,2.9030839669015975,1.1401822218335855,-0.006717839319282361,0.7823570787372804,0.3862050876012223,-0.4460485219456556,-0.2475716116033651
| 3,430
|
Processing of smdt1
| 6
| 10
| 2.0309
| 0.042265
|
Q8IYU8,Q8WWC4,Q9Y4W6,Q99623,Q9UJZ1,O75439
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
259,49,281,217,224,285
|
285,1636,397,259,635,49,918,217,224,281
|
1.2018332759105956,-0.07817009911541081,0.9314960696962661,1.3036465389571528,0.5866553931117515,2.816737247023802,0.3409796634418964,1.4442806151058643,1.4243227288831315,1.2426977300728366
| 3,430
|
Mitochondrial carrier protein [IPR002067]
| 8
| 10
| 2.019997
| 0.043384
|
P12236,P12235,P05141,O75746,Q9H936,P53007,Q9UJS0,Q9BQT8
|
Sequence
|
InterPro Family
|
interpro_family
|
320,319,357,484,469,525,446,58
|
591,484,357,319,320,525,973,58,469,446
|
0.6086282374406464,0.7608365031739326,1.015570844477996,1.0988413665209409,1.0988413665209409,0.6959430870585518,0.29549744978102077,2.6770943999274905,0.8038230816292831,0.8465930328531754
| 3,430
|
Acyl-CoA dehydrogenase-like, C-terminal [IPR036250]
| 6
| 9
| 2.017607
| 0.043632
|
Q709F0,O15254,Q9H845,Q15067,P26440,P11310
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
491,380,72,107,434,219
|
380,219,434,842,490,107,491,951,72
|
0.9525914548719056,1.4243227288831315,0.8465930328531754,0.3862050876012223,0.7608365031739326,2.098713770993166,0.7608365031739326,0.31827093163679243,2.5355539747519957
| 3,430
|
Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily [IPR009100]
| 6
| 9
| 2.017607
| 0.043632
|
Q709F0,O15254,Q9H845,Q15067,P26440,P11310
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
491,380,72,107,434,219
|
380,219,434,842,490,107,491,951,72
|
0.9525914548719056,1.4243227288831315,0.8465930328531754,0.3862050876012223,0.7608365031739326,2.098713770993166,0.7608365031739326,0.31827093163679243,2.5355539747519957
| 3,430
|
Acyl-CoA oxidase/dehydrogenase, central domain [IPR006091]
| 6
| 9
| 2.017607
| 0.043632
|
Q709F0,O15254,Q9H845,Q15067,P26440,P11310
|
Sequence
|
InterPro Domain
|
interpro_domain
|
491,380,72,107,434,219
|
380,219,434,842,490,107,491,951,72
|
0.9525914548719056,1.4243227288831315,0.8465930328531754,0.3862050876012223,0.7608365031739326,2.098713770993166,0.7608365031739326,0.31827093163679243,2.5355539747519957
| 3,430
|
Abc type transporter activity
| 6
| 10
| 2.003767
| 0.045095
|
Q9HD20,Q03519,P08183,Q03518,O75027,O15533
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
197,129,410,112,213,343
|
1880,343,213,410,761,112,129,197,1464,501
|
-0.1987783830519874,1.0364629614668819,1.4442806151058643,0.8891496313255574,0.4535712115110452,2.061430403594576,1.891865759389253,1.5434239324829382,0.0169517671877368,0.7392609323561437
| 3,430
|
Ketoacidosis
| 7
| 10
| 1.985296
| 0.047112
|
P35610,P09001,P08574,P53985,Q9HCC0,P22033,Q4G176
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
230,424,143,209,184,304,221
|
143,424,304,1899,434,230,209,2972,221,184
|
1.83467532885005,0.8678977997586717,1.1401822218335855,-0.1987783830519874,0.8465930328531754,1.3842754439377112,1.464195049648795,-0.7808039974572951,1.4243227288831315,1.6024030309091215
| 3,430
|
Inner mitochondrial membrane protein complex
| 33
| 76
| 4.050584
| 0.000051
|
O75964,P48047,O43676,P51970,P14927,O75306,Q16718,P36542,P20674,O00217,P56385,P06576,Q9P0J0,Q99595,Q9UDW1,Q9NX63,O60830,P14406,P00403,Q9Y6M9,O75489,Q13505,Q99623,O75431,Q86Y39,P08574,P22695,P13073,Q16891,P24539,P14854,P25705,P03886
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
2,521,4,397,14,514,146,281,659,656,412,40,45,703,579,578,56,560,558,449,710,588,89,219,352,223,232,108,360,109,484,501,500
|
656,2858,2585,1367,4,3021,56,2587,514,2369,219,1435,710,793,2,1514,3175,2060,1515,558,500,40,223,1663,1664,1811,108,560,484,14,3211,3142,659,2332,232,109,501,2886,2483,1473,1400,281,1814,1713,521,3124,397,3294,412,588,146,1180,360,1967,2634,2755,1999,352,1529,1419,1092,1763,703,89,3129,760,1319,578,45,579,1590,895,819,843,1774,449
|
0.6933477721843095,-0.8190021137923701,-0.5908507122210328,0.15034720133396523,4.551842722059264,-0.9834347839005033,2.547409768053795,-0.5908507122210328,0.8693977289284917,-0.4654184907728244,1.4714808810674698,0.10738556209941592,0.6276115039211269,0.5620305844376072,5.167196520160504,0.06449608277835585,-1.2074277428722162,-0.2759883981888322,0.06449608277835585,0.8032512025014997,0.8914804711800896,2.8041124444238252,1.448967877539575,-0.04241010240522003,-0.04241010240522003,-0.12760615078476442,2.0394981091593998,0.8032512025014997,0.9135801145844248,3.537101859755954,-1.2882658134684348,-1.1465830158056964,0.6933477721843095,-0.44444629644309747,1.4264710812485106,2.0394981091593998,0.8914804711800896,-0.8396256696385406,-0.5282207546911941,0.0859317852989234,0.12885737883854684,1.269449542990556,-0.12760615078476442,-0.06373662902854216,0.8693977289284917,-1.1059176287710073,1.0465312750378557,-1.548678875208257,1.0243308327237213,0.7812363588966038,1.8111031480459492,0.2796623627116229,1.1132326864910351,-0.21250736851480986,-0.6116888886017858,-0.7155893800863863,-0.23368633339360326,1.1354997578192654,0.06449608277835585,0.12885737883854684,0.34456029993080256,-0.08504483643208101,0.6495063733352072,2.177283285595381,-1.1059176287710073,0.6057338953933035,0.19338072765197223,0.8032512025014997,2.7105571292304815,0.8032512025014997,0.02167903874393584,0.4966058497171867,0.5620305844376072,0.5402049440683143,-0.08504483643208101,0.9799801607699364
| 3,430
|
Mitochondrial transport
| 30
| 85
| 3.615441
| 0.0003
|
Q14849,O75964,P48047,Q9NS69,Q10713,P36542,P56385,P51572,P12235,Q99797,P06576,Q8N4H5,Q96EK5,Q9P0J0,O60830,Q9UBX3,Q8TB36,P07900,P49257,O14737,Q9Y5J9,Q15070,O75431,Q9Y5Z4,Q9UII2,P24539,Q9Y5L4,Q96QK1,Q9UJZ1,P25705
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
1,2,521,7,414,281,412,410,406,438,40,546,548,45,56,320,191,314,562,206,84,589,219,94,363,109,114,507,390,501
|
984,206,2585,1546,3375,56,709,219,2300,793,2,987,2098,2477,1235,2770,3130,2302,2331,40,314,1629,901,406,936,713,109,501,3059,1667,2592,1746,281,2560,603,521,1295,562,3094,2236,410,2948,1111,3294,412,1405,995,414,1,589,2754,1051,1967,2634,1684,1722,1250,2453,2116,546,191,2118,548,507,2577,703,438,1188,760,2390,7,45,2191,320,363,2546,390,1590,2986,819,843,1774,84,114,94
|
0.4096172898409424,1.5165554046538223,-0.5908507122210328,0.04307848903912287,-2.0198432297961233,2.547409768053795,0.6276115039211269,1.4714808810674698,-0.4234551139739826,0.5620305844376072,5.167196520160504,0.4096172898409424,-0.2971114238181862,-0.5282207546911941,0.23648587072936555,-0.736311113618571,-1.1262605148954412,-0.4234551139739826,-0.44444629644309747,2.8041124444238252,1.2024003828056788,-0.02106529204966477,0.4748324586170831,1.0243308327237213,0.45307654705381356,0.6276115039211269,2.0394981091593998,0.8914804711800896,-1.024343149410197,-0.04241010240522003,-0.5908507122210328,-0.08504483643208101,1.269449542990556,-0.569993271061387,0.7592385640896675,0.8693977289284917,0.19338072765197223,0.8032512025014997,-1.0651708848393058,-0.38141593935161383,1.0243308327237213,-0.9013775888027895,0.3229099381780773,-1.548678875208257,1.0243308327237213,0.12885737883854684,0.4096172898409424,1.0243308327237213,5.2664158196818995,0.7812363588966038,-0.7155893800863863,0.3662283341069291,-0.21250736851480986,-0.6116888886017858,-0.04241010240522003,-0.06373662902854216,0.23648587072936555,-0.5073057591164345,-0.2971114238181862,0.8252830651235218,1.6068977874861423,-0.2971114238181862,0.8252830651235218,0.8914804711800896,-0.569993271061387,0.6495063733352072,1.0021471184507622,0.2796623627116229,0.6057338953933035,-0.4654184907728244,4.283733422464173,2.7105571292304815,-0.3393012744587857,1.2024003828056788,1.1132326864910351,-0.5491166052451673,1.0687484169607406,0.02167903874393584,-0.9219218352181526,0.5620305844376072,0.5402049440683143,-0.08504483643208101,2.2233352367607586,2.0165882176348306,2.131292988821414
| 3,430
|
Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins
| 31
| 63
| 3.470842
| 0.000519
|
O75964,P48047,O43676,P51970,P14927,O75306,Q16718,P36542,P20674,Q9P032,O00217,Q9BQ95,P56385,P06576,Q9P0J0,Q9UDW1,Q12931,P00403,Q9Y6M9,Q8N183,O75489,Q9NPL8,Q86Y39,P08574,P22695,P13073,P24539,P14854,P42704,P25705,P03886
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
2,521,4,397,14,514,146,281,659,813,656,687,412,40,45,579,694,558,449,68,710,476,352,223,232,108,109,484,739,501,500
|
656,2858,1367,4,3021,2025,2587,514,2369,1435,710,1234,793,2,1514,3175,2060,1515,558,500,40,223,1663,1664,108,2884,484,14,3211,3142,659,2332,232,109,501,2886,2483,1473,281,2946,739,1713,521,3124,397,3294,412,694,1601,146,1180,1821,352,68,1058,687,3101,1191,476,813,45,579,449
|
0.6933477721843095,-0.8190021137923701,0.15034720133396523,4.551842722059264,-0.9834347839005033,-0.254846688969337,-0.5908507122210328,0.8693977289284917,-0.4654184907728244,0.10738556209941592,0.6276115039211269,0.23648587072936555,0.5620305844376072,5.167196520160504,0.06449608277835585,-1.2074277428722162,-0.2759883981888322,0.06449608277835585,0.8032512025014997,0.8914804711800896,2.8041124444238252,1.448967877539575,-0.04241010240522003,-0.04241010240522003,2.0394981091593998,-0.8396256696385406,0.9135801145844248,3.537101859755954,-1.2882658134684348,-1.1465830158056964,0.6933477721843095,-0.44444629644309747,1.4264710812485106,2.0394981091593998,0.8914804711800896,-0.8396256696385406,-0.5282207546911941,0.0859317852989234,1.269449542990556,-0.9013775888027895,0.6057338953933035,-0.06373662902854216,0.8693977289284917,-1.1059176287710073,1.0465312750378557,-1.548678875208257,1.0243308327237213,0.6495063733352072,0.0002977667180233936,1.8111031480459492,0.2796623627116229,-0.12760615078476442,1.1354997578192654,2.431327036159296,0.3662283341069291,0.6714184729428473,-1.0651708848393058,0.2796623627116229,0.9356966299859146,0.5620305844376072,2.7105571292304815,0.8032512025014997,0.9799801607699364
| 3,430
|
Cilium assembly
| 22
| 69
| 3.400179
| 0.000673
|
O95613,P41208,Q10713,Q13561,P06493,Q9BV73,O15078,O94927,Q96A65,P61981,O60645,O75935,Q14203,P78371,P07900,P62258,Q9Y496,Q96KP1,Q9UPT5,Q9UBN7,Q99996,A6NIH7
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
515,19,414,415,543,309,173,175,307,427,423,443,188,446,314,67,205,492,113,246,387,127
|
790,127,844,173,821,423,1912,443,175,515,3005,1132,543,988,314,1632,1879,1551,2591,968,2273,19,1079,1521,679,1845,1815,2485,2103,1141,427,67,2991,2139,446,414,1406,415,1581,1526,188,833,569,1484,696,1216,1822,886,3272,780,1057,2002,1185,307,492,2123,387,1220,309,2083,3086,1863,956,2225,246,3246,113,1456,205
|
0.5620305844376072,1.9251046821425566,0.518396688704323,1.6748229295823038,0.5402049440683143,1.0021471184507622,-0.191309831206804,0.9799801607699364,1.6748229295823038,0.8693977289284917,-0.9629504767360699,0.3012772815040069,0.8252830651235218,0.4096172898409424,1.2024003828056788,-0.02106529204966477,-0.17009375816547115,0.04307848903912287,-0.5908507122210328,0.43133814681776855,-0.40244498209708657,3.204350628748325,0.34456029993080256,0.06449608277835585,0.6714184729428473,-0.14885918591010985,-0.12760615078476442,-0.5282207546911941,-0.2971114238181862,0.3012772815040069,1.0021471184507622,2.431327036159296,-0.942446145812876,-0.31821572844136564,0.9799801607699364,1.0243308327237213,0.12885737883854684,1.0243308327237213,0.02167903874393584,0.06449608277835585,1.6068977874861423,0.5402049440683143,0.8032512025014997,0.0859317852989234,0.6495063733352072,0.2580652147528089,-0.12760615078476442,0.4966058497171867,-1.4489421856887923,0.5838735785783277,0.3662283341069291,-0.23368633339360326,0.2796623627116229,1.2247336356763627,0.9135801145844248,-0.2971114238181862,1.0687484169607406,0.2580652147528089,1.2247336356763627,-0.2759883981888322,-1.0447671183808418,-0.14885918591010985,0.45307654705381356,-0.36036802408587215,1.4039905186201218,-1.3687716700453372,2.0165882176348306,0.10738556209941592,1.5391168723820783
| 3,430
|
Chaperone
| 20
| 40
| 3.319791
| 0.000901
|
Q04917,Q99426,P08238,P49368,P27348,Q99471,P31946,P61981,O60476,P63104,Q14203,Q12931,P07900,P78371,O75347,Q58FF6,P62258,Q9UHV9,Q14BN4,P61604
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
284,160,404,679,677,436,178,427,51,316,188,694,314,446,313,196,67,598,85,118
|
984,3166,2366,51,313,986,2557,314,404,1264,1551,677,1812,178,938,1521,679,1845,1815,118,2069,427,67,316,446,284,694,188,85,943,2681,196,2384,1686,160,436,1356,760,2263,598
|
0.4096172898409424,-1.1871666764907194,-0.4654184907728244,2.6172401968299104,1.2024003828056788,0.4096172898409424,-0.569993271061387,1.2024003828056788,1.0243308327237213,0.21492436389411237,0.04307848903912287,0.6714184729428473,-0.12760615078476442,1.6748229295823038,0.45307654705381356,0.06449608277835585,0.6714184729428473,-0.14885918591010985,-0.12760615078476442,1.9708151956500113,-0.2759883981888322,1.0021471184507622,2.431327036159296,1.2024003828056788,0.9799801607699364,1.269449542990556,0.6495063733352072,1.6068977874861423,2.200301566033099,0.45307654705381356,-0.6533072855099272,1.5842880896557086,-0.4654184907728244,-0.04241010240522003,1.7656129496664057,1.0021471184507622,0.17185499556109507,0.6057338953933035,-0.38141593935161383,0.7812363588966038
| 3,430
|
Cardiac muscle contraction
| 12
| 21
| 3.295296
| 0.000983
|
P14406,P00403,P09493,P16615,P08574,P22695,P13073,P14854,P14927,P06753,P67936,Q9UDW1
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
560,558,3,602,223,232,108,484,14,176,16,579
|
1367,558,1261,176,223,3,1663,1664,108,560,484,14,3211,602,659,232,1473,1713,2275,16,579
|
0.15034720133396523,0.8032512025014997,0.21492436389411237,1.6748229295823038,1.448967877539575,4.649741438376801,-0.04241010240522003,-0.04241010240522003,2.0394981091593998,0.8032512025014997,0.9135801145844248,3.537101859755954,-1.2882658134684348,0.7592385640896675,0.6933477721843095,1.4264710812485106,0.0859317852989234,-0.06373662902854216,-0.40244498209708657,3.4417439480452012,0.8032512025014997
| 3,430
|
Mitochondrial respiratory chain complex assembly
| 14
| 39
| 3.208843
| 0.001333
|
Q9Y6M9,Q8N183,Q69YU5,O43676,Q86Y39,Q9H061,P51970,Q6DKK2,Q9P0J0,Q9Y2R0,Q00059,Q16718,P03886,Q9BSK2
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
449,68,35,4,352,39,397,267,45,49,50,146,500,287
|
656,4,3021,2025,2587,514,1435,710,1234,1514,2060,2770,1515,500,2886,1713,397,50,589,146,1180,35,267,1821,352,68,1058,1092,287,3101,39,1191,2852,813,45,1590,49,819,449
|
0.6933477721843095,4.551842722059264,-0.9834347839005033,-0.254846688969337,-0.5908507122210328,0.8693977289284917,0.10738556209941592,0.6276115039211269,0.23648587072936555,0.06449608277835585,-0.2759883981888322,-0.736311113618571,0.06449608277835585,0.8914804711800896,-0.8396256696385406,-0.06373662902854216,1.0465312750378557,2.64054700619109,0.7812363588966038,1.8111031480459492,0.2796623627116229,2.8509790683742646,1.314231136956651,-0.12760615078476442,1.1354997578192654,2.431327036159296,0.3662283341069291,0.34456029993080256,1.269449542990556,-1.0651708848393058,2.8275383601959625,0.2796623627116229,-0.7983588379042941,0.5620305844376072,2.7105571292304815,0.02167903874393584,2.6638687791403814,0.5620305844376072,0.9799801607699364
| 3,430
|
Huntingtons disease
| 32
| 81
| 3.151867
| 0.001622
|
P48047,O43676,P51970,P14927,P27695,O75306,Q16718,P36542,P20674,O00291,P42574,O00217,Q13561,O15514,P12235,P06576,Q9UDW1,Q00059,Q14203,P14406,P00403,P42858,Q9Y6M9,O75489,P45880,P08574,P22695,P13073,P24539,P14854,P25705,P21796
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
521,4,397,14,641,514,146,281,659,531,533,656,415,163,406,40,579,50,188,560,558,690,449,710,603,223,232,108,109,484,501,249
|
656,531,2858,1367,163,4,3021,2587,514,2369,1435,710,793,1290,1514,3175,2060,1915,1515,558,3362,2302,2331,40,223,1019,2130,1663,1664,406,1811,108,560,484,14,3211,2133,1784,3142,659,249,2332,232,109,2270,501,641,2886,1048,2483,1473,281,533,690,603,1713,521,3124,397,770,3222,1207,50,745,995,1599,1408,415,188,3029,146,1180,2458,3018,1421,1610,579,2091,2296,2549,449
|
0.6933477721843095,0.8473319171085857,-0.8190021137923701,0.15034720133396523,1.742891610000047,4.551842722059264,-0.9834347839005033,-0.5908507122210328,0.8693977289284917,-0.4654184907728244,0.10738556209941592,0.6276115039211269,0.5620305844376072,0.19338072765197223,0.06449608277835585,-1.2074277428722162,-0.2759883981888322,-0.191309831206804,0.06449608277835585,0.8032512025014997,-1.8837389062755159,-0.4234551139739826,-0.44444629644309747,2.8041124444238252,1.448967877539575,0.387914008197925,-0.31821572844136564,-0.04241010240522003,-0.04241010240522003,1.0243308327237213,-0.12760615078476442,2.0394981091593998,0.8032512025014997,0.9135801145844248,3.537101859755954,-1.2882658134684348,-0.31821572844136564,-0.10633468895957496,-1.1465830158056964,0.6933477721843095,1.3815262161857498,-0.44444629644309747,1.4264710812485106,2.0394981091593998,-0.40244498209708657,0.8914804711800896,0.7152942406319166,-0.8396256696385406,0.3662283341069291,-0.5282207546911941,0.0859317852989234,1.269449542990556,0.8473319171085857,0.6495063733352072,0.7592385640896675,-0.06373662902854216,0.8693977289284917,-1.1059176287710073,1.0465312750378557,0.5838735785783277,-1.3084235436014806,0.2580652147528089,2.64054700619109,0.6057338953933035,0.4096172898409424,0.0002977667180233936,0.12885737883854684,1.0243308327237213,1.6068977874861423,-0.9834347839005033,1.8111031480459492,0.2796623627116229,-0.5073057591164345,-0.9629504767360699,0.12885737883854684,0.0002977667180233936,0.8032512025014997,-0.2759883981888322,-0.40244498209708657,-0.5491166052451673,0.9799801607699364
| 3,430
|
Organelle biogenesis and maintenance
| 37
| 104
| 3.111571
| 0.001861
|
O75964,P48047,P00367,O95613,P41208,Q10713,P54646,P36542,Q13561,P56385,P06493,P06576,Q04837,Q9BV73,O15078,O94927,Q96A65,Q00059,P61981,Q9NX63,Q15019,O60645,O75935,Q14203,P07900,P78371,P62258,Q9Y496,O75431,Q96KP1,Q16891,P24539,Q9UPT5,Q9UBN7,P25705,Q99996,A6NIH7
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
2,521,516,515,19,414,151,281,415,412,543,40,168,309,173,175,307,50,427,578,569,423,443,188,314,446,67,205,219,492,360,109,113,246,501,387,127
|
790,127,1366,844,173,821,423,2625,219,1912,443,793,2,175,515,3005,516,3362,1132,543,40,988,314,1632,1879,1551,2591,109,501,968,2273,281,1814,19,1079,521,1521,3168,679,1845,1815,3320,2485,1748,151,3294,412,2103,1141,427,67,2991,2139,446,50,168,414,1406,588,415,1581,1526,188,833,569,1484,2680,696,360,2755,1216,1999,1822,886,2637,3272,780,1057,2289,2002,3018,1185,307,492,2389,2123,387,1220,3129,309,2083,3086,1316,1863,956,1319,578,2225,246,3246,113,1456,205,819
|
0.5620305844376072,1.9251046821425566,0.15034720133396523,0.518396688704323,1.6748229295823038,0.5402049440683143,1.0021471184507622,-0.6116888886017858,1.4714808810674698,-0.191309831206804,0.9799801607699364,0.5620305844376072,5.167196520160504,1.6748229295823038,0.8693977289284917,-0.9629504767360699,0.8693977289284917,-1.8837389062755159,0.3012772815040069,0.8252830651235218,2.8041124444238252,0.4096172898409424,1.2024003828056788,-0.02106529204966477,-0.17009375816547115,0.04307848903912287,-0.5908507122210328,2.0394981091593998,0.8914804711800896,0.43133814681776855,-0.40244498209708657,1.269449542990556,-0.12760615078476442,3.204350628748325,0.34456029993080256,0.8693977289284917,0.06449608277835585,-1.1871666764907194,0.6714184729428473,-0.14885918591010985,-0.12760615078476442,-1.6478801727558299,-0.5282207546911941,-0.08504483643208101,1.7883501373217856,-1.548678875208257,1.0243308327237213,-0.2971114238181862,0.3012772815040069,1.0021471184507622,2.431327036159296,-0.942446145812876,-0.31821572844136564,0.9799801607699364,2.64054700619109,1.7201861433390337,1.0243308327237213,0.12885737883854684,0.7812363588966038,1.0243308327237213,0.02167903874393584,0.06449608277835585,1.6068977874861423,0.5402049440683143,0.8032512025014997,0.0859317852989234,-0.6533072855099272,0.6495063733352072,1.1132326864910351,-0.7155893800863863,0.2580652147528089,-0.23368633339360326,-0.12760615078476442,0.4966058497171867,-0.6116888886017858,-1.4489421856887923,0.5838735785783277,0.3662283341069291,-0.40244498209708657,-0.23368633339360326,-0.9629504767360699,0.2796623627116229,1.2247336356763627,0.9135801145844248,-0.4654184907728244,-0.2971114238181862,1.0687484169607406,0.2580652147528089,-1.1059176287710073,1.2247336356763627,-0.2759883981888322,-1.0447671183808418,0.19338072765197223,-0.14885918591010985,0.45307654705381356,0.19338072765197223,0.8032512025014997,-0.36036802408587215,1.4039905186201218,-1.3687716700453372,2.0165882176348306,0.10738556209941592,1.5391168723820783,0.5620305844376072
| 3,430
|
Cis golgi network
| 7
| 16
| 3.086715
| 0.002024
|
P30533,Q9NPR9,Q14789,P24390,Q8TBA6,O00461,Q08379
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
99,297,225,13,63,153,155
|
153,845,1130,13,99,992,155,225,1086,63,921,2002,2184,387,297,1946
|
1.7656129496664057,0.518396688704323,0.3012772815040069,3.5848660368475693,2.0853645337676863,0.4096172898409424,1.7656129496664057,1.448967877539575,0.34456029993080256,2.4545133476558236,0.4748324586170831,-0.23368633339360326,-0.3393012744587857,1.0687484169607406,1.2470833648713042,-0.191309831206804
| 3,430
|
Electron transport chain oxphos system in mitochondria
| 21
| 52
| 3.063176
| 0.00219
|
O75964,P48047,O43676,P51970,P14927,O75306,Q16718,P36542,P56385,P12235,P06576,Q9UDW1,P14406,Q9Y6M9,Q9UII2,P22695,P13073,P24539,P14854,P25705,P03886
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
2,521,4,397,14,514,146,281,412,406,40,579,560,449,363,232,108,109,484,501,500
|
656,2858,1367,4,3021,2587,514,2369,1435,710,1234,793,2,1514,3175,2060,1515,558,500,2331,40,1663,1664,406,1811,108,560,484,14,3211,3142,659,2332,232,109,501,2886,2483,1473,281,1713,521,3124,397,3294,412,146,1180,2635,579,363,449
|
0.6933477721843095,-0.8190021137923701,0.15034720133396523,4.551842722059264,-0.9834347839005033,-0.5908507122210328,0.8693977289284917,-0.4654184907728244,0.10738556209941592,0.6276115039211269,0.23648587072936555,0.5620305844376072,5.167196520160504,0.06449608277835585,-1.2074277428722162,-0.2759883981888322,0.06449608277835585,0.8032512025014997,0.8914804711800896,-0.44444629644309747,2.8041124444238252,-0.04241010240522003,-0.04241010240522003,1.0243308327237213,-0.12760615078476442,2.0394981091593998,0.8032512025014997,0.9135801145844248,3.537101859755954,-1.2882658134684348,-1.1465830158056964,0.6933477721843095,-0.44444629644309747,1.4264710812485106,2.0394981091593998,0.8914804711800896,-0.8396256696385406,-0.5282207546911941,0.0859317852989234,1.269449542990556,-0.06373662902854216,0.8693977289284917,-1.1059176287710073,1.0465312750378557,-1.548678875208257,1.0243308327237213,1.8111031480459492,0.2796623627116229,-0.6116888886017858,0.8032512025014997,1.1132326864910351,0.9799801607699364
| 3,430
|
Progeriaassociated lipodystrophy
| 7
| 10
| 3.050848
| 0.002282
|
Q03252,P28340,P49354,P20700,P02545,O75844,O60725
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
34,254,203,77,46,322,86
|
86,2197,322,46,1262,77,254,407,203,34
|
2.177283285595381,-0.36036802408587215,1.1800836337709497,2.6872054940154664,0.21492436389411237,2.3156233598343645,1.359078200582899,1.0243308327237213,1.5391168723820783,2.8979047777720357
| 3,430
|
Intracellular calcium-sensing protein
| 7
| 16
| 3.029964
| 0.002446
|
Q99584,Q14257,O43852,P41208,P0DP25,Q9BRK5,P80303
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
42,236,48,19,338,23,62
|
48,338,1371,19,743,2411,62,2832,236,457,2714,1350,1529,1563,42,23
|
2.6638687791403814,1.1577834161963467,0.15034720133396523,3.204350628748325,0.6057338953933035,-0.4863716580376144,2.4545133476558236,-0.7776958844485033,1.4264710812485106,0.9578299883515244,-0.6740874247602239,0.17185499556109507,0.06449608277835585,0.04307848903912287,2.8041124444238252,3.109797184993122
| 3,430
|
Calmodulin
| 7
| 16
| 3.029964
| 0.002446
|
Q99584,Q14257,O43852,P41208,P0DP25,Q9BRK5,P80303
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
42,236,48,19,338,23,62
|
48,338,1371,19,743,2411,62,2832,236,457,2714,1350,1529,1563,42,23
|
2.6638687791403814,1.1577834161963467,0.15034720133396523,3.204350628748325,0.6057338953933035,-0.4863716580376144,2.4545133476558236,-0.7776958844485033,1.4264710812485106,0.9578299883515244,-0.6740874247602239,0.17185499556109507,0.06449608277835585,0.04307848903912287,2.8041124444238252,3.109797184993122
| 3,430
|
Establishment of protein localization to mitochondrial membrane
| 6
| 19
| 3.027739
| 0.002464
|
Q9NS69,Q9P0J0,O14737,Q9Y5L4,Q9Y5J9,P07900
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
7,45,206,114,84,314
|
1874,206,987,314,338,1667,1746,995,589,2634,2118,7,45,1590,819,843,1774,84,114
|
-0.17009375816547115,1.5165554046538223,0.4096172898409424,1.2024003828056788,1.1577834161963467,-0.04241010240522003,-0.08504483643208101,0.4096172898409424,0.7812363588966038,-0.6116888886017858,-0.2971114238181862,4.283733422464173,2.7105571292304815,0.02167903874393584,0.5620305844376072,0.5402049440683143,-0.08504483643208101,2.2233352367607586,2.0165882176348306
| 3,430
|
Oxidative phosphorylation
| 27
| 61
| 3.000293
| 0.002697
|
O75964,P48047,O43676,P51970,P14927,O75306,Q16718,P36542,P20674,P56385,O00217,Q9Y5K8,P06576,Q9UDW1,P14406,P00403,Q9Y6M9,Q93050,Q9Y487,Q86Y39,P08574,P22695,P13073,P24539,P14854,P25705,P03886
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
2,521,4,397,14,514,146,281,659,412,656,288,40,579,560,558,449,461,727,352,223,232,108,109,484,501,500
|
656,2858,1367,4,3021,2587,514,2369,1435,710,793,2,1514,3175,2060,1515,558,500,40,223,1663,1664,108,560,484,14,3211,3142,659,3023,3076,2332,232,109,501,2886,2483,1473,281,1137,1791,1713,521,3124,397,3294,412,1637,3321,2730,146,1180,2635,352,461,2931,579,1622,727,288,449
|
0.6933477721843095,-0.8190021137923701,0.15034720133396523,4.551842722059264,-0.9834347839005033,-0.5908507122210328,0.8693977289284917,-0.4654184907728244,0.10738556209941592,0.6276115039211269,0.5620305844376072,5.167196520160504,0.06449608277835585,-1.2074277428722162,-0.2759883981888322,0.06449608277835585,0.8032512025014997,0.8914804711800896,2.8041124444238252,1.448967877539575,-0.04241010240522003,-0.04241010240522003,2.0394981091593998,0.8032512025014997,0.9135801145844248,3.537101859755954,-1.2882658134684348,-1.1465830158056964,0.6933477721843095,-0.9834347839005033,-1.0447671183808418,-0.44444629644309747,1.4264710812485106,2.0394981091593998,0.8914804711800896,-0.8396256696385406,-0.5282207546911941,0.0859317852989234,1.269449542990556,0.3012772815040069,-0.10633468895957496,-0.06373662902854216,0.8693977289284917,-1.1059176287710073,1.0465312750378557,-1.548678875208257,1.0243308327237213,-0.02106529204966477,-1.6478801727558299,-0.6948481366740377,1.8111031480459492,0.2796623627116229,-0.6116888886017858,1.1354997578192654,0.9578299883515244,-0.8808134501833325,0.8032512025014997,0.0002977667180233936,0.6276115039211269,1.269449542990556,0.9799801607699364
| 3,430
|
Parkinsons disease
| 24
| 55
| 2.998876
| 0.00271
|
P48047,O43676,P51970,P14927,O75306,Q16718,P36542,P20674,P42574,P12235,P06576,Q9UDW1,P14406,P00403,Q9Y6M9,P45880,P08574,P22695,P13073,P24539,P14854,P25705,P03886,P21796
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
521,4,397,14,514,146,281,659,533,406,40,579,560,558,449,603,223,232,108,109,484,501,500,249
|
656,2858,1367,4,3021,2587,514,2369,1435,710,793,1514,3175,2060,1515,558,500,2331,40,223,1663,1664,406,1811,108,560,484,14,3211,3142,659,249,2332,1333,232,109,501,2886,2483,1473,281,533,603,1713,521,3124,397,1405,1599,146,1180,3329,579,2549,449
|
0.6933477721843095,-0.8190021137923701,0.15034720133396523,4.551842722059264,-0.9834347839005033,-0.5908507122210328,0.8693977289284917,-0.4654184907728244,0.10738556209941592,0.6276115039211269,0.5620305844376072,0.06449608277835585,-1.2074277428722162,-0.2759883981888322,0.06449608277835585,0.8032512025014997,0.8914804711800896,-0.44444629644309747,2.8041124444238252,1.448967877539575,-0.04241010240522003,-0.04241010240522003,1.0243308327237213,-0.12760615078476442,2.0394981091593998,0.8032512025014997,0.9135801145844248,3.537101859755954,-1.2882658134684348,-1.1465830158056964,0.6933477721843095,1.3815262161857498,-0.44444629644309747,0.17185499556109507,1.4264710812485106,2.0394981091593998,0.8914804711800896,-0.8396256696385406,-0.5282207546911941,0.0859317852989234,1.269449542990556,0.8473319171085857,0.7592385640896675,-0.06373662902854216,0.8693977289284917,-1.1059176287710073,1.0465312750378557,0.12885737883854684,0.0002977667180233936,1.8111031480459492,0.2796623627116229,-1.66765560705382,0.8032512025014997,-0.5491166052451673,0.9799801607699364
| 3,430
|
centrosome
| 16
| 36
| 2.977871
| 0.002903
|
P06493,Q04917,O43237,P62258,Q9NSK0,P27348,Q9BZD4,Q9BV73,P33176,P31946,P41208,Q10713,P61981,P0DP25,P63104,Q13561
|
Localization
|
OpenCell Localization
|
opencell_localization
|
543,284,311,67,402,677,596,309,110,178,19,414,427,338,316,415
|
311,1287,1045,3039,543,338,1632,1879,677,178,110,2234,19,1714,2485,427,67,316,284,1341,414,1406,910,415,1526,833,696,2384,1822,2955,2504,309,596,1120,402,1067
|
1.2024003828056788,0.19338072765197223,0.3662283341069291,-1.0038990229805613,0.8252830651235218,1.1577834161963467,-0.02106529204966477,-0.17009375816547115,0.6714184729428473,1.6748229295823038,2.0165882176348306,-0.38141593935161383,3.204350628748325,-0.06373662902854216,-0.5282207546911941,1.0021471184507622,2.431327036159296,1.2024003828056788,1.269449542990556,0.17185499556109507,1.0243308327237213,0.12885737883854684,0.4748324586170831,1.0243308327237213,0.06449608277835585,0.5402049440683143,0.6495063733352072,-0.4654184907728244,-0.12760615078476442,-0.9013775888027895,-0.5282207546911941,1.2247336356763627,0.7812363588966038,0.3229099381780773,1.0465312750378557,0.3662283341069291
| 3,430
|
Cellular response to heat
| 10
| 33
| 2.95515
| 0.003125
|
O15514,Q58FF6,P62258,Q9H078,P09601,Q13535,O95391,P42345,P12270,P07900
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
163,196,67,333,71,292,70,233,107,314
|
163,1289,1462,70,1235,1707,314,404,71,1073,107,1632,1879,2973,1168,233,2138,882,67,661,292,1410,196,2458,3018,3085,629,1765,333,2222,2913,1621,1734
|
1.742891610000047,0.19338072765197223,0.0859317852989234,2.40815588672373,0.23648587072936555,-0.06373662902854216,1.2024003828056788,1.0243308327237213,2.40815588672373,0.34456029993080256,2.0394981091593998,-0.02106529204966477,-0.17009375816547115,-0.9219218352181526,0.2796623627116229,1.4264710812485106,-0.31821572844136564,0.4966058497171867,2.431327036159296,0.6933477721843095,1.2470833648713042,0.12885737883854684,1.5842880896557086,-0.5073057591164345,-0.9629504767360699,-1.0447671183808418,0.7372578479891295,-0.08504483643208101,1.1800836337709497,-0.36036802408587215,-0.8602294627439812,0.0002977667180233936,-0.06373662902854216
| 3,430
|
Muscle contraction
| 10
| 30
| 2.952398
| 0.003153
|
P09493,Q13177,P08670,Q05682,P06753,P67936,P18206,P04083,Q99996,Q9NYL9
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
3,195,11,204,176,16,393,583,387,611
|
1660,583,1261,176,822,1465,11,3,602,1632,1879,393,852,1919,1843,3301,2437,2275,743,16,204,2709,195,2071,2280,2177,387,2325,611,1362
|
-0.04241010240522003,0.7812363588966038,0.21492436389411237,1.6748229295823038,0.5402049440683143,0.0859317852989234,3.824533083456319,4.649741438376801,0.7592385640896675,-0.02106529204966477,-0.17009375816547115,1.0465312750378557,0.518396688704323,-0.191309831206804,-0.14885918591010985,-1.5685621747527327,-0.5073057591164345,-0.40244498209708657,0.6057338953933035,3.4417439480452012,1.5391168723820783,-0.6740874247602239,1.5842880896557086,-0.2759883981888322,-0.40244498209708657,-0.3393012744587857,1.0687484169607406,-0.4234551139739826,0.7592385640896675,0.17185499556109507
| 3,430
|
Sensory processing of sound by outer hair cells of the cochlea
| 6
| 14
| 2.952383
| 0.003153
|
Q01082,Q6IBS0,P26038,P15311,Q13813,P35241
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
256,143,90,87,119,25
|
1948,1126,87,1919,90,25,444,2109,256,1342,119,1445,143,842
|
-0.21250736851480986,0.3012772815040069,2.177283285595381,-0.191309831206804,2.131292988821414,3.0861951345931513,0.9799801607699364,-0.2971114238181862,1.359078200582899,0.17185499556109507,1.9708151956500113,0.10738556209941592,1.8338719570141517,0.5402049440683143
| 3,430
|
membrane traffic protein
| 27
| 66
| 2.949869
| 0.003179
|
Q5JRA6,Q9BRG1,P43307,Q8IUD2,O43747,Q9NX40,Q8WUX9,Q96PC5,Q08379,P51572,Q96A65,P54920,Q9UK41,O60645,O60763,P50570,P49257,Q5VIR6,Q9H223,Q9H4M9,Q96RL7,O00429,Q9UBC2,Q9UPT5,Q96QK1,O60313,A6NIH7
|
Functions
|
Panther Protein class
|
panther_protein_class
|
525,529,132,134,636,422,537,29,155,410,307,302,580,423,312,194,562,722,73,344,610,600,632,113,507,616,127
|
127,1874,600,2023,636,616,423,312,1547,1290,1915,3374,2747,1881,1266,714,2630,132,939,562,194,410,302,3417,1207,1580,2678,155,859,1084,2174,996,525,722,1855,134,2661,537,1310,307,1421,1311,29,507,610,2911,1827,1729,529,836,73,867,1937,344,1063,422,1121,3049,1323,632,1867,580,113,2055,1870,2720
|
1.9251046821425566,-0.17009375816547115,0.7592385640896675,-0.254846688969337,0.7152942406319166,0.7372578479891295,1.0021471184507622,1.2024003828056788,0.04307848903912287,0.19338072765197223,-0.191309831206804,-2.0004675616234437,-0.7155893800863863,-0.17009375816547115,0.21492436389411237,0.6276115039211269,-0.6116888886017858,1.8794568708577217,0.45307654705381356,0.8032512025014997,1.5842880896557086,1.0243308327237213,1.2247336356763627,-3.455511531066017,0.2580652147528089,0.02167903874393584,-0.6533072855099272,1.7656129496664057,0.518396688704323,0.34456029993080256,-0.3393012744587857,0.4096172898409424,0.8693977289284917,0.6276115039211269,-0.14885918591010985,1.8794568708577217,-0.6325077598761806,0.8473319171085857,0.19338072765197223,1.2247336356763627,0.12885737883854684,0.19338072765197223,2.9919327835623593,0.8914804711800896,0.7592385640896675,-0.8602294627439812,-0.12760615078476442,-0.06373662902854216,0.8693977289284917,0.5402049440683143,2.40815588672373,0.518396688704323,-0.191309831206804,1.1577834161963467,0.3662283341069291,1.0243308327237213,0.3229099381780773,-1.0038990229805613,0.19338072765197223,0.7372578479891295,-0.14885918591010985,0.8032512025014997,2.0165882176348306,-0.254846688969337,-0.14885918591010985,-0.6740874247602239
| 3,430
|
Protein insertion into membrane
| 8
| 29
| 2.928455
| 0.003407
|
Q15006,Q9NS69,Q9P0J0,O14737,Q96A33,Q9Y5L4,Q9Y5J9,P07900
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
189,7,45,206,238,114,84,314
|
206,766,1231,987,314,1667,1746,879,3302,995,189,589,1558,2634,2415,1249,1604,2118,238,705,7,403,45,1590,819,843,1774,84,114
|
1.5165554046538223,0.5838735785783277,0.23648587072936555,0.4096172898409424,1.2024003828056788,-0.04241010240522003,-0.08504483643208101,0.4966058497171867,-1.5685621747527327,0.4096172898409424,1.6068977874861423,0.7812363588966038,0.04307848903912287,-0.6116888886017858,-0.4863716580376144,0.23648587072936555,0.0002977667180233936,-0.2971114238181862,1.4264710812485106,0.6495063733352072,4.283733422464173,1.0465312750378557,2.7105571292304815,0.02167903874393584,0.5620305844376072,0.5402049440683143,-0.08504483643208101,2.2233352367607586,2.0165882176348306
| 3,430
|
Intermediate filament
| 9
| 21
| 2.913795
| 0.003571
|
Q03252,P58107,P08670,P20700,P02545,Q16352,P07197,Q15149,Q9UPN3
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
34,485,11,77,46,82,55,416,321
|
2623,46,900,55,11,2885,1957,77,1440,545,1714,3201,485,2240,34,416,82,950,1832,1571,321
|
-0.6116888886017858,2.6872054940154664,0.4748324586170831,2.5706715559059043,3.824533083456319,-0.8396256696385406,-0.21250736851480986,2.3156233598343645,0.10738556209941592,0.8252830651235218,-0.06373662902854216,-1.2680873203022425,0.9135801145844248,-0.38141593935161383,2.8979047777720357,1.0243308327237213,2.2233352367607586,0.45307654705381356,-0.12760615078476442,0.04307848903912287,1.2024003828056788
| 3,430
|
Mitochondrial protein import
| 17
| 36
| 2.911949
| 0.003592
|
Q9Y512,P12235,P08574,Q9NS69,Q8N4H5,P06576,Q9HAV7,Q99595,Q13505,Q9Y5L4,Q9Y5J9,Q10713,Q9NX63,O60830,P25705,O75431,P21796
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
819,406,223,7,546,40,760,703,588,114,84,414,578,56,501,219,249
|
2585,1546,56,2431,219,2300,1985,987,3130,40,223,901,406,1811,249,501,1814,1524,414,588,2754,1967,1684,546,703,2981,760,7,578,2546,1590,819,843,1774,84,114
|
-0.5908507122210328,0.04307848903912287,2.547409768053795,-0.5073057591164345,1.4714808810674698,-0.4234551139739826,-0.23368633339360326,0.4096172898409424,-1.1262605148954412,2.8041124444238252,1.448967877539575,0.4748324586170831,1.0243308327237213,-0.12760615078476442,1.3815262161857498,0.8914804711800896,-0.12760615078476442,0.06449608277835585,1.0243308327237213,0.7812363588966038,-0.7155893800863863,-0.21250736851480986,-0.04241010240522003,0.8252830651235218,0.6495063733352072,-0.9219218352181526,0.6057338953933035,4.283733422464173,0.8032512025014997,-0.5491166052451673,0.02167903874393584,0.5620305844376072,0.5402049440683143,-0.08504483643208101,2.2233352367607586,2.0165882176348306
| 3,430
|
Primary mitochondrial disease
| 37
| 97
| 2.889384
| 0.00386
|
O43676,Q6DKK2,P14927,O75306,Q9NWS8,P20674,O00217,P12235,Q99797,Q9P0J0,Q5T2R2,Q9Y2R0,Q00059,Q9UBX3,P00403,Q8N183,Q9Y6M9,O75489,Q9NPL8,P03886,Q07021,Q70HW3,Q9BQT8,P52815,Q86Y39,P82650,P08574,P22695,Q9BW92,P13073,P14854,P09001,Q7L0Y3,P82930,O60313,P25705,Q8NI60
|
Drugs and Diseases
|
Protein Atlas Disease involvement
|
protein_atlas_disease_involvement
|
4,267,14,514,18,659,656,406,438,45,305,49,50,320,558,68,449,710,476,500,217,754,93,91,352,349,223,232,362,108,484,735,628,505,616,501,252
|
656,2858,1367,4,3021,2025,616,2587,514,2369,710,1513,1234,2060,2770,558,500,1841,223,735,406,108,484,14,3142,659,232,501,2886,2483,1138,739,2889,1713,2375,3124,91,2521,349,505,50,217,1180,2634,1052,998,2951,305,2712,2755,267,1490,754,2635,628,3336,352,2536,68,1758,252,1058,2287,1280,1092,2007,1763,923,2389,438,2982,1498,93,3101,362,1902,1191,1193,1318,476,18,1944,813,45,2876,320,1590,49,1123,1011,2158,2855,2721,1736,843,1227,449
|
0.6933477721843095,-0.8190021137923701,0.15034720133396523,4.551842722059264,-0.9834347839005033,-0.254846688969337,0.7372578479891295,-0.5908507122210328,0.8693977289284917,-0.4654184907728244,0.6276115039211269,0.06449608277835585,0.23648587072936555,-0.2759883981888322,-0.736311113618571,0.8032512025014997,0.8914804711800896,-0.14885918591010985,1.448967877539575,0.6057338953933035,1.0243308327237213,2.0394981091593998,0.9135801145844248,3.537101859755954,-1.1465830158056964,0.6933477721843095,1.4264710812485106,0.8914804711800896,-0.8396256696385406,-0.5282207546911941,0.3012772815040069,0.6057338953933035,-0.8396256696385406,-0.06373662902854216,-0.4654184907728244,-1.1059176287710073,2.131292988821414,-0.5491166052451673,1.1354997578192654,0.8914804711800896,2.64054700619109,1.4940100655111697,0.2796623627116229,-0.6116888886017858,0.3662283341069291,0.4096172898409424,-0.9013775888027895,1.2247336356763627,-0.6740874247602239,-0.7155893800863863,1.314231136956651,0.0859317852989234,0.6057338953933035,-0.6116888886017858,0.7372578479891295,-1.70714122168277,1.1354997578192654,-0.5491166052451673,2.431327036159296,-0.08504483643208101,1.3815262161857498,0.3662283341069291,-0.40244498209708657,0.21492436389411237,0.34456029993080256,-0.23368633339360326,-0.08504483643208101,0.4748324586170831,-0.4654184907728244,1.0021471184507622,-0.9219218352181526,0.0859317852989234,2.131292988821414,-1.0651708848393058,1.1132326864910351,-0.17009375816547115,0.2796623627116229,0.2796623627116229,0.19338072765197223,0.9356966299859146,3.251714214631556,-0.191309831206804,0.5620305844376072,2.7105571292304815,-0.8190021137923701,1.2024003828056788,0.02167903874393584,2.6638687791403814,0.3229099381780773,0.4096172898409424,-0.31821572844136564,-0.7983588379042941,-0.6740874247602239,-0.06373662902854216,0.5402049440683143,0.2580652147528089,0.9799801607699364
| 3,430
|
Sensory processing of sound
| 7
| 19
| 2.886997
| 0.003889
|
Q13813,Q01082,Q6IBS0,P52907,P15311,P35241,P26038
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
119,256,143,301,87,25,90
|
1948,1126,87,852,1919,90,25,444,991,1672,301,3009,2109,256,1342,119,1445,143,842
|
-0.21250736851480986,0.3012772815040069,2.177283285595381,0.518396688704323,-0.191309831206804,2.131292988821414,3.0861951345931513,0.9799801607699364,0.4096172898409424,-0.04241010240522003,1.2247336356763627,-0.9629504767360699,-0.2971114238181862,1.359078200582899,0.17185499556109507,1.9708151956500113,0.10738556209941592,1.8338719570141517,0.5402049440683143
| 3,430
|
Negative regulation of protein polymerization
| 12
| 30
| 2.871532
| 0.004085
|
Q13813,Q15691,Q01082,P45880,O15020,P16949,Q9NUQ9,Q6IBS0,Q02790,P52907,P35241,Q9NYL9
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
119,696,256,603,634,8,630,143,368,301,25,611
|
634,709,1626,1132,3210,8,1843,2799,25,1670,2272,603,991,1672,301,2562,256,368,1598,2204,119,2381,696,143,2312,1424,1313,630,611,1196
|
0.7152942406319166,0.6276115039211269,-0.02106529204966477,0.3012772815040069,-1.2882658134684348,4.186646783930239,-0.14885918591010985,-0.7570132956764223,3.0861951345931513,-0.04241010240522003,-0.40244498209708657,0.7592385640896675,0.4096172898409424,-0.04241010240522003,1.2247336356763627,-0.569993271061387,1.359078200582899,1.0909822301776992,0.0002977667180233936,-0.36036802408587215,1.9708151956500113,-0.4654184907728244,0.6495063733352072,1.8338719570141517,-0.4234551139739826,0.12885737883854684,0.19338072765197223,0.7372578479891295,0.7592385640896675,0.2796623627116229
| 3,430
|
Structural constituent of cytoskeleton
| 7
| 35
| 2.855188
| 0.004301
|
P09493,P08670,Q9Y5K6,Q16352,P07197,Q13813,P26038
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
3,11,247,82,55,119,90
|
531,634,1511,2367,3255,1132,900,55,988,11,3,2404,1957,90,2272,972,3010,1848,2139,256,2491,119,1581,1445,416,1179,82,1585,3002,1220,2083,1196,842,1362,247
|
0.8473319171085857,0.7152942406319166,0.06449608277835585,-0.4654184907728244,-1.4088990437313549,0.3012772815040069,0.4748324586170831,2.5706715559059043,0.4096172898409424,3.824533083456319,4.649741438376801,-0.4863716580376144,-0.21250736851480986,2.131292988821414,-0.40244498209708657,0.43133814681776855,-0.9629504767360699,-0.14885918591010985,-0.31821572844136564,1.359078200582899,-0.5282207546911941,1.9708151956500113,0.02167903874393584,0.10738556209941592,1.0243308327237213,0.2796623627116229,2.2233352367607586,0.02167903874393584,-0.942446145812876,0.2580652147528089,-0.2759883981888322,0.2796623627116229,0.5402049440683143,0.17185499556109507,1.4039905186201218
| 3,430
|
Programmed cell death
| 39
| 99
| 2.844747
| 0.004445
|
O75955,O43242,Q9UNM6,P08670,Q9Y3B8,Q92530,Q8WUX9,Q15149,P42574,Q04917,O00560,P51572,Q9NR28,P28070,P02545,P31946,P61981,P62191,P63104,Q13464,P48556,P07900,Q13177,P62258,Q9Y5V3,P17980,P49354,P20700,Q16543,Q07021,Q15008,P61289,P62195,Q14254,P09429,O00429,O00231,P26583,Q13813
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
377,375,269,11,278,538,537,416,533,284,154,410,552,41,46,178,427,184,316,430,445,314,195,67,599,454,203,77,340,217,470,213,214,221,465,600,356,621,119
|
356,2699,1573,600,1777,154,897,1979,375,616,2401,377,46,2302,3341,314,11,465,3400,1957,3372,3368,454,1990,77,1992,902,2233,2434,621,677,1169,737,41,2199,3025,1439,1667,178,2829,1670,1790,2168,533,798,445,1553,203,2304,2065,410,940,3241,2377,1882,1635,213,427,184,214,67,2239,316,2991,284,1598,1026,217,2201,995,2175,195,772,430,1176,119,2993,221,1890,3383,470,416,340,721,2661,537,538,3190,2836,1934,552,2877,2468,2192,1159,1734,269,278,599
|
1.1132326864910351,-0.6740874247602239,0.02167903874393584,0.7592385640896675,-0.10633468895957496,1.7656129496664057,0.4748324586170831,-0.23368633339360326,1.0687484169607406,0.7372578479891295,-0.4863716580376144,1.0687484169607406,2.6872054940154664,-0.4234551139739826,-1.7465394682740971,1.2024003828056788,3.824533083456319,0.9356966299859146,-2.6088832120872674,-0.21250736851480986,-1.9810691920969703,-1.9616481810876696,0.9578299883515244,-0.23368633339360326,2.3156233598343645,-0.23368633339360326,0.4748324586170831,-0.38141593935161383,-0.5073057591164345,0.7372578479891295,0.6714184729428473,0.2796623627116229,0.6057338953933035,2.8041124444238252,-0.36036802408587215,-0.9834347839005033,0.10738556209941592,-0.04241010240522003,1.6748229295823038,-0.7776958844485033,-0.04241010240522003,-0.10633468895957496,-0.3393012744587857,0.8473319171085857,0.5620305844376072,0.9799801607699364,0.04307848903912287,1.5391168723820783,-0.4234551139739826,-0.2759883981888322,1.0243308327237213,0.45307654705381356,-1.3687716700453372,-0.4654184907728244,-0.17009375816547115,-0.02106529204966477,1.4940100655111697,1.0021471184507622,1.65216523300499,1.4940100655111697,2.431327036159296,-0.38141593935161383,1.2024003828056788,-0.942446145812876,1.269449542990556,0.0002977667180233936,0.387914008197925,1.4940100655111697,-0.36036802408587215,0.4096172898409424,-0.3393012744587857,1.5842880896557086,0.5838735785783277,1.0021471184507622,0.2796623627116229,1.9708151956500113,-0.942446145812876,1.4714808810674698,-0.17009375816547115,-2.1740240119418117,0.9356966299859146,1.0243308327237213,1.1577834161963467,0.6276115039211269,-0.6325077598761806,0.8473319171085857,0.8473319171085857,-1.227668237248389,-0.7776958844485033,-0.191309831206804,0.8252830651235218,-0.8190021137923701,-0.5073057591164345,-0.3393012744587857,0.3012772815040069,-0.06373662902854216,1.314231136956651,1.291832142745204,0.7812363588966038
| 3,430
|
Translation factor
| 10
| 27
| 2.826396
| 0.004708
|
P23588,Q14152,Q15056,O75153,P60228,P29692,O75822,P24534,Q86TB9,P78344
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
96,257,329,66,262,75,270,299,251,283
|
1950,2551,2059,66,270,1707,1016,1133,96,299,75,2889,1239,2708,3201,262,1142,413,283,1299,2112,257,568,329,1347,251,894
|
-0.21250736851480986,-0.569993271061387,-0.2759883981888322,2.431327036159296,1.291832142745204,-0.06373662902854216,0.387914008197925,0.3012772815040069,2.108321019317115,1.2247336356763627,2.361859163920826,-0.8396256696385406,0.23648587072936555,-0.6740874247602239,-1.2680873203022425,1.3366464985559088,0.3012772815040069,1.0243308327237213,1.269449542990556,0.19338072765197223,-0.2971114238181862,1.359078200582899,0.8032512025014997,1.1800836337709497,0.17185499556109507,1.3815262161857498,0.4966058497171867
| 3,430
|
Nadh dehydrogenase complex assembly
| 12
| 28
| 2.814947
| 0.004879
|
Q9Y6M9,Q8N183,O43676,Q9H061,P51970,Q9P0J0,O75306,Q16718,Q15070,P03886,Q86Y39,O00217
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
449,68,4,39,397,45,514,146,589,500,352,656
|
656,4,3021,2587,514,1435,710,1514,2060,1515,500,2886,397,589,146,1180,1821,352,68,1058,1092,3101,39,1191,813,45,1590,449
|
0.6933477721843095,4.551842722059264,-0.9834347839005033,-0.5908507122210328,0.8693977289284917,0.10738556209941592,0.6276115039211269,0.06449608277835585,-0.2759883981888322,0.06449608277835585,0.8914804711800896,-0.8396256696385406,1.0465312750378557,0.7812363588966038,1.8111031480459492,0.2796623627116229,-0.12760615078476442,1.1354997578192654,2.431327036159296,0.3662283341069291,0.34456029993080256,-1.0651708848393058,2.8275383601959625,0.2796623627116229,0.5620305844376072,2.7105571292304815,0.02167903874393584,0.9799801607699364
| 3,430
|
Centriolar satellite
| 11
| 35
| 2.81313
| 0.004906
|
Q9Y448,P33176,O95613,Q8WXW3,O43809,Q9Y5K6,P41208,O43169,Q86UY6,Q9P260,Q15907
|
Localization
|
Protein Atlas Subcellular
|
protein_atlas_subcellular_location_all
|
172,110,515,371,513,247,19,115,22,319,159
|
1574,115,2969,513,1101,1013,515,3178,110,19,2109,994,2173,1799,2204,2450,1484,696,159,1602,1491,886,22,3117,2000,371,1971,319,553,172,1362,1737,2093,247,2022
|
0.02167903874393584,1.993693905134758,-0.9219218352181526,0.8693977289284917,0.3229099381780773,0.387914008197925,0.8693977289284917,-1.2074277428722162,2.0165882176348306,3.204350628748325,-0.2971114238181862,0.4096172898409424,-0.3393012744587857,-0.10633468895957496,-0.36036802408587215,-0.5073057591164345,0.0859317852989234,0.6495063733352072,1.7656129496664057,0.0002977667180233936,0.0859317852989234,0.4966058497171867,3.1334137797857156,-1.085554403485646,-0.23368633339360326,1.0909822301776992,-0.21250736851480986,1.2024003828056788,0.8252830651235218,1.6974965747963648,0.17185499556109507,-0.06373662902854216,-0.2759883981888322,1.4039905186201218,-0.23368633339360326
| 3,430
|
Oxidative phosphorylation
| 27
| 61
| 2.758422
| 0.005808
|
O75964,P48047,O43676,P51970,P14927,O75306,Q16718,P36542,P20674,Q96QE5,P14635,Q9BSK2,P06493,P56385,P06576,Q9UDW1,P14406,P00403,Q9Y6M9,O75323,P08574,P22695,P13073,P24539,Q9UJZ1,P25705,P03886
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
2,521,4,397,14,514,146,281,659,286,658,287,543,412,40,579,560,558,449,464,223,232,108,109,390,501,500
|
656,2858,1367,4,3021,2587,514,464,2369,1435,710,793,2,1514,3175,2060,1515,558,500,543,40,223,2268,1664,108,560,658,14,3211,3142,659,232,109,501,1203,2886,3059,2483,1473,1136,281,768,1713,521,3124,397,882,3294,412,744,146,1180,2417,2635,286,3329,287,3414,579,390,449
|
0.6933477721843095,-0.8190021137923701,0.15034720133396523,4.551842722059264,-0.9834347839005033,-0.5908507122210328,0.8693977289284917,0.9356966299859146,-0.4654184907728244,0.10738556209941592,0.6276115039211269,0.5620305844376072,5.167196520160504,0.06449608277835585,-1.2074277428722162,-0.2759883981888322,0.06449608277835585,0.8032512025014997,0.8914804711800896,0.8252830651235218,2.8041124444238252,1.448967877539575,-0.40244498209708657,-0.04241010240522003,2.0394981091593998,0.8032512025014997,0.6933477721843095,3.537101859755954,-1.2882658134684348,-1.1465830158056964,0.6933477721843095,1.4264710812485106,2.0394981091593998,0.8914804711800896,0.2580652147528089,-0.8396256696385406,-1.024343149410197,-0.5282207546911941,0.0859317852989234,0.3012772815040069,1.269449542990556,0.5838735785783277,-0.06373662902854216,0.8693977289284917,-1.1059176287710073,1.0465312750378557,0.4966058497171867,-1.548678875208257,1.0243308327237213,0.6057338953933035,1.8111031480459492,0.2796623627116229,-0.4863716580376144,-0.6116888886017858,1.269449542990556,-1.66765560705382,1.269449542990556,-3.298052234067302,0.8032512025014997,1.0687484169607406,0.9799801607699364
| 3,430
|
Proton transmembrane transporter activity
| 17
| 35
| 2.75472
| 0.005874
|
P00403,O75964,P48047,Q93050,P12235,O95202,P08574,P56385,P06576,P13073,P24539,P14854,Q9UDW1,P36542,P25705,P20674,Q9Y5K8
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
558,2,521,461,406,638,223,412,40,108,109,484,579,281,501,659,288
|
793,2,638,558,2331,40,223,1664,406,108,484,659,3023,3076,109,501,1473,281,1137,1791,1713,521,3294,412,1637,2488,884,2635,461,3160,2814,579,1622,727,288
|
0.5620305844376072,5.167196520160504,0.7152942406319166,0.8032512025014997,-0.44444629644309747,2.8041124444238252,1.448967877539575,-0.04241010240522003,1.0243308327237213,2.0394981091593998,0.9135801145844248,0.6933477721843095,-0.9834347839005033,-1.0447671183808418,2.0394981091593998,0.8914804711800896,0.0859317852989234,1.269449542990556,0.3012772815040069,-0.10633468895957496,-0.06373662902854216,0.8693977289284917,-1.548678875208257,1.0243308327237213,-0.02106529204966477,-0.5282207546911941,0.4966058497171867,-0.6116888886017858,0.9578299883515244,-1.1668850851929853,-0.7570132956764223,0.8032512025014997,0.0002977667180233936,0.6276115039211269,1.269449542990556
| 3,430
|
Calcium-binding protein
| 8
| 21
| 2.752096
| 0.005922
|
P43307,Q99584,Q14257,O43852,P41208,P0DP25,Q9BRK5,P80303
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
132,42,236,48,19,338,23,62
|
48,338,3293,1371,19,132,743,2411,62,2832,236,457,2714,1350,1529,1563,3019,42,1729,23,818
|
2.6638687791403814,1.1577834161963467,-1.548678875208257,0.15034720133396523,3.204350628748325,1.8794568708577217,0.6057338953933035,-0.4863716580376144,2.4545133476558236,-0.7776958844485033,1.4264710812485106,0.9578299883515244,-0.6740874247602239,0.17185499556109507,0.06449608277835585,0.04307848903912287,-0.9629504767360699,2.8041124444238252,-0.06373662902854216,3.109797184993122,0.5620305844376072
| 3,430
|
Intermediate filament cytoskeleton
| 11
| 37
| 2.739188
| 0.006159
|
Q03252,Q99471,P58107,P08670,P20700,P02545,Q9UNZ2,Q16352,P07197,Q15149,Q9UPN3
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
34,436,485,11,77,46,441,82,55,416,321
|
2623,2401,46,900,55,11,2885,1957,77,1440,545,1714,1403,1845,3201,485,2240,34,2950,416,82,1447,1147,3083,2418,1930,1149,436,950,1832,2223,1732,1942,1571,761,441,321
|
-0.6116888886017858,-0.4863716580376144,2.6872054940154664,0.4748324586170831,2.5706715559059043,3.824533083456319,-0.8396256696385406,-0.21250736851480986,2.3156233598343645,0.10738556209941592,0.8252830651235218,-0.06373662902854216,0.12885737883854684,-0.14885918591010985,-1.2680873203022425,0.9135801145844248,-0.38141593935161383,2.8979047777720357,-0.9013775888027895,1.0243308327237213,2.2233352367607586,0.10738556209941592,0.3012772815040069,-1.0447671183808418,-0.4863716580376144,-0.191309831206804,0.3012772815040069,1.0021471184507622,0.45307654705381356,-0.12760615078476442,-0.36036802408587215,-0.06373662902854216,-0.191309831206804,0.04307848903912287,0.6057338953933035,1.0021471184507622,1.2024003828056788
| 3,430
|
Inorganic molecular entity transmembrane transporter activity
| 34
| 71
| 2.733631
| 0.006264
|
Q13423,O75964,P48047,O95202,Q6P4Q7,O43681,Q9C0H2,P36542,P20674,P56385,Q9Y5K8,P12235,Q99797,P06576,O75947,Q9UDW1,Q9UBX3,Q93034,P00403,Q93050,P07355,Q9Y487,P55011,Q9HD20,P45880,P20020,P08574,P16615,P13073,P24539,P14854,Q9Y6M7,P25705,P21796
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
884,2,521,638,399,766,150,281,659,412,288,406,438,40,793,579,320,58,558,461,822,727,829,227,603,852,223,602,108,109,484,896,501,249
|
2622,766,793,2,638,558,1261,2331,40,3176,822,1465,1916,223,1395,1664,406,108,484,602,852,659,3023,3076,249,1919,109,501,1473,281,1137,1791,603,1713,521,2274,829,3294,412,1637,3302,2488,1639,1242,884,2413,913,3421,399,2635,1056,1419,58,461,3160,1004,438,2014,150,1936,2814,227,320,579,1622,1324,2549,727,288,2857,896
|
-0.6116888886017858,0.5838735785783277,0.5620305844376072,5.167196520160504,0.7152942406319166,0.8032512025014997,0.21492436389411237,-0.44444629644309747,2.8041124444238252,-1.2074277428722162,0.5402049440683143,0.0859317852989234,-0.191309831206804,1.448967877539575,0.12885737883854684,-0.04241010240522003,1.0243308327237213,2.0394981091593998,0.9135801145844248,0.7592385640896675,0.518396688704323,0.6933477721843095,-0.9834347839005033,-1.0447671183808418,1.3815262161857498,-0.191309831206804,2.0394981091593998,0.8914804711800896,0.0859317852989234,1.269449542990556,0.3012772815040069,-0.10633468895957496,0.7592385640896675,-0.06373662902854216,0.8693977289284917,-0.40244498209708657,0.5402049440683143,-1.548678875208257,1.0243308327237213,-0.02106529204966477,-1.5685621747527327,-0.5282207546911941,-0.02106529204966477,0.23648587072936555,0.4966058497171867,-0.4863716580376144,0.4748324586170831,-4.547079791194694,1.0465312750378557,-0.6116888886017858,0.3662283341069291,0.12885737883854684,2.547409768053795,0.9578299883515244,-1.1668850851929853,0.4096172898409424,1.0021471184507622,-0.23368633339360326,1.8111031480459492,-0.191309831206804,-0.7570132956764223,1.448967877539575,1.2024003828056788,0.8032512025014997,0.0002977667180233936,0.19338072765197223,-0.5491166052451673,0.6276115039211269,1.269449542990556,-0.7983588379042941,0.4966058497171867
| 3,430
|
Respiratory chain
| 13
| 33
| 2.712881
| 0.00667
|
Q9Y6M9,O43676,P08574,P51970,P22695,Q6DKK2,Q9P0J0,P14927,O75306,Q9UDW1,Q16718,P03886,Q86Y39
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
449,4,223,397,232,267,45,14,514,579,146,500,352
|
656,2858,1367,4,3021,2587,514,2369,1435,710,1514,3175,2060,1515,558,500,223,14,3142,232,2886,1473,1713,3124,397,146,1180,267,352,1092,45,579,449
|
0.6933477721843095,-0.8190021137923701,0.15034720133396523,4.551842722059264,-0.9834347839005033,-0.5908507122210328,0.8693977289284917,-0.4654184907728244,0.10738556209941592,0.6276115039211269,0.06449608277835585,-1.2074277428722162,-0.2759883981888322,0.06449608277835585,0.8032512025014997,0.8914804711800896,1.448967877539575,3.537101859755954,-1.1465830158056964,1.4264710812485106,-0.8396256696385406,0.0859317852989234,-0.06373662902854216,-1.1059176287710073,1.0465312750378557,1.8111031480459492,0.2796623627116229,1.314231136956651,1.1354997578192654,0.34456029993080256,2.7105571292304815,0.8032512025014997,0.9799801607699364
| 3,430
|
Sensory perception
| 8
| 29
| 2.71165
| 0.006695
|
Q13813,Q01082,P49354,Q6IBS0,P52907,P15311,P35241,P26038
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
119,256,203,143,301,87,25,90
|
1948,1126,87,1632,852,1919,90,1786,1667,25,444,991,1672,203,740,3078,301,3009,2307,2109,256,2923,1342,119,1445,143,2283,2420,842
|
-0.21250736851480986,0.3012772815040069,2.177283285595381,-0.02106529204966477,0.518396688704323,-0.191309831206804,2.131292988821414,-0.10633468895957496,-0.04241010240522003,3.0861951345931513,0.9799801607699364,0.4096172898409424,-0.04241010240522003,1.5391168723820783,0.6057338953933035,-1.0447671183808418,1.2247336356763627,-0.9629504767360699,-0.4234551139739826,-0.2971114238181862,1.359078200582899,-0.8808134501833325,0.17185499556109507,1.9708151956500113,0.10738556209941592,1.8338719570141517,-0.40244498209708657,-0.4863716580376144,0.5402049440683143
| 3,430
|
ATPase, AAA-type, core [IPR003959]
| 16
| 30
| 2.652859
| 0.007981
|
Q9H078,Q9UN37,P40937,P17980,Q8WVB6,P43686,P36776,Q5T9A4,Q9Y4W6,Q15645,P62191,P55072,P62195,Q96TA2,Q9NVI7,P46459
|
Sequence
|
InterPro Domain
|
interpro_domain
|
333,980,241,454,237,798,395,317,895,650,184,882,214,187,354,939
|
1594,1984,986,454,2436,2800,1294,1790,395,241,798,939,882,184,214,2239,650,317,2756,2001,1492,237,1971,187,1973,333,354,980,1590,895
|
0.0002977667180233936,-0.23368633339360326,0.4096172898409424,0.9578299883515244,-0.5073057591164345,-0.7570132956764223,0.19338072765197223,-0.10633468895957496,1.0465312750378557,1.4039905186201218,0.5620305844376072,0.45307654705381356,0.4966058497171867,1.65216523300499,1.4940100655111697,-0.38141593935161383,0.7152942406319166,1.2024003828056788,-0.7155893800863863,-0.23368633339360326,0.0859317852989234,1.4264710812485106,-0.21250736851480986,1.6295235104710366,-0.21250736851480986,1.1800836337709497,1.1354997578192654,0.43133814681776855,0.02167903874393584,0.4966058497171867
| 3,430
|
Translation initiation factor
| 8
| 21
| 2.594312
| 0.009478
|
P23588,Q14152,Q15056,O75153,P60228,O75822,Q86TB9,P78344
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
96,257,329,66,262,270,251,283
|
1950,2551,2059,66,270,1707,1016,1133,96,1239,2708,3201,262,413,283,1299,2112,257,329,251,894
|
-0.21250736851480986,-0.569993271061387,-0.2759883981888322,2.431327036159296,1.291832142745204,-0.06373662902854216,0.387914008197925,0.3012772815040069,2.108321019317115,0.23648587072936555,-0.6740874247602239,-1.2680873203022425,1.3366464985559088,1.0243308327237213,1.269449542990556,0.19338072765197223,-0.2971114238181862,1.359078200582899,1.1800836337709497,1.3815262161857498,0.4966058497171867
| 3,430
|
Alzheimers disease
| 22
| 62
| 2.593419
| 0.009503
|
P48047,O43676,P51970,P14927,O75306,Q16718,P36542,P20674,P42574,P06576,Q9UDW1,P14406,P00403,Q9Y6M9,P0DP25,P16615,P08574,P22695,P13073,P24539,P14854,P25705
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
521,4,397,14,514,146,281,659,533,40,579,560,558,449,338,602,223,232,108,109,484,501
|
3360,656,2858,1367,4,3021,2587,514,2369,1435,710,793,1514,3175,2060,1515,558,2402,2099,40,1955,223,1663,338,1664,108,560,796,484,14,3211,602,2655,3142,659,2332,232,109,501,1169,2886,1439,2483,1473,281,533,1713,521,1553,3124,397,1882,1639,2923,942,146,1180,2048,2961,579,1621,449
|
-1.844649948742758,0.6933477721843095,-0.8190021137923701,0.15034720133396523,4.551842722059264,-0.9834347839005033,-0.5908507122210328,0.8693977289284917,-0.4654184907728244,0.10738556209941592,0.6276115039211269,0.5620305844376072,0.06449608277835585,-1.2074277428722162,-0.2759883981888322,0.06449608277835585,0.8032512025014997,-0.4863716580376144,-0.2971114238181862,2.8041124444238252,-0.21250736851480986,1.448967877539575,-0.04241010240522003,1.1577834161963467,-0.04241010240522003,2.0394981091593998,0.8032512025014997,0.5620305844376072,0.9135801145844248,3.537101859755954,-1.2882658134684348,0.7592385640896675,-0.6325077598761806,-1.1465830158056964,0.6933477721843095,-0.44444629644309747,1.4264710812485106,2.0394981091593998,0.8914804711800896,0.2796623627116229,-0.8396256696385406,0.10738556209941592,-0.5282207546911941,0.0859317852989234,1.269449542990556,0.8473319171085857,-0.06373662902854216,0.8693977289284917,0.04307848903912287,-1.1059176287710073,1.0465312750378557,-0.17009375816547115,-0.02106529204966477,-0.8808134501833325,0.45307654705381356,1.8111031480459492,0.2796623627116229,-0.254846688969337,-0.9013775888027895,0.8032512025014997,0.0002977667180233936,0.9799801607699364
| 3,430
|
Proton transporting two sector atpase complex
| 9
| 22
| 2.591461
| 0.009557
|
O75964,Q93050,P06576,P56385,P24539,P36542,P25705,Q8N511,Q9Y5K8
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
2,461,40,412,109,281,501,57,288
|
793,2,40,3023,3076,109,501,281,1137,1791,521,3294,412,1637,2730,57,461,1763,2122,1622,727,288
|
0.5620305844376072,5.167196520160504,2.8041124444238252,-0.9834347839005033,-1.0447671183808418,2.0394981091593998,0.8914804711800896,1.269449542990556,0.3012772815040069,-0.10633468895957496,0.8693977289284917,-1.548678875208257,1.0243308327237213,-0.02106529204966477,-0.6948481366740377,2.547409768053795,0.9578299883515244,-0.08504483643208101,-0.2971114238181862,0.0002977667180233936,0.6276115039211269,1.269449542990556
| 3,430
|
Apoptotic cleavage of cellular proteins
| 8
| 20
| 2.582875
| 0.009798
|
P51572,Q13813,P08670,P49354,P20700,P02545,Q13464,Q15149
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
410,119,11,203,77,46,430,416
|
46,11,1957,77,2829,1670,533,203,410,1882,1598,2201,430,119,2993,416,721,2877,2468,2192
|
2.6872054940154664,3.824533083456319,-0.21250736851480986,2.3156233598343645,-0.7776958844485033,-0.04241010240522003,0.8473319171085857,1.5391168723820783,1.0243308327237213,-0.17009375816547115,0.0002977667180233936,-0.36036802408587215,1.0021471184507622,1.9708151956500113,-0.942446145812876,1.0243308327237213,0.6276115039211269,-0.8190021137923701,-0.5073057591164345,-0.3393012744587857
| 3,430
|
Spectrin/alpha-actinin [IPR018159]
| 8
| 13
| 2.578027
| 0.009937
|
Q01082,O43707,O75962,P46939,Q9UPN3,Q13813,Q15149,P12814
|
Sequence
|
InterPro Repeat
|
interpro_repeat
|
256,289,106,425,321,119,416,466
|
634,289,106,466,1957,2437,425,256,2240,119,416,1149,321
|
0.7152942406319166,1.2470833648713042,2.0394981091593998,0.9356966299859146,-0.21250736851480986,-0.5073057591164345,1.0021471184507622,1.359078200582899,-0.38141593935161383,1.9708151956500113,1.0243308327237213,0.3012772815040069,1.2024003828056788
| 3,430
|
Intra golgi traffic
| 8
| 15
| 2.576127
| 0.009991
|
Q13190,P83436,Q96MW5,P54920,O60476,Q9NRW7,O00461,Q8TBA6
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
165,428,447,302,51,419,153,63
|
153,876,51,1130,3054,939,302,428,165,1086,63,447,1827,419,581
|
1.7656129496664057,0.4966058497171867,2.6172401968299104,0.3012772815040069,-1.024343149410197,0.45307654705381356,1.2247336356763627,1.0021471184507622,1.742891610000047,0.34456029993080256,2.4545133476558236,0.9799801607699364,-0.12760615078476442,1.0243308327237213,0.8032512025014997
| 3,430
|
calmodulin-related
| 7
| 14
| 2.575834
| 0.01
|
Q99584,Q14257,O43852,P41208,P0DP25,Q9BRK5,P80303
|
Functions
|
Panther Protein class
|
panther_protein_class
|
42,236,48,19,338,23,62
|
48,338,3301,1371,19,2411,62,2832,236,457,1529,3019,42,23
|
2.6638687791403814,1.1577834161963467,-1.5685621747527327,0.15034720133396523,3.204350628748325,-0.4863716580376144,2.4545133476558236,-0.7776958844485033,1.4264710812485106,0.9578299883515244,0.06449608277835585,-0.9629504767360699,2.8041124444238252,3.109797184993122
| 3,430
|
Negative regulation of supramolecular fiber organization
| 19
| 54
| 2.559316
| 0.010488
|
Q01082,O15020,P16949,O15212,Q6IBS0,P35241,Q99471,Q13136,P52907,Q15691,Q13177,Q9UHV9,O75146,Q92974,Q9NYL9,Q9NUQ9,Q9UBN7,Q02790,Q13813
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
256,634,8,12,143,25,436,52,301,696,195,598,709,92,611,630,246,368,119
|
634,12,1574,1983,709,1626,1132,3210,1165,8,1843,2799,25,1670,2272,2438,991,1672,301,2562,2069,2991,256,368,1598,2201,2204,52,195,119,2381,696,143,2312,755,1822,2418,2955,92,2787,436,1424,3281,1313,2323,630,2465,611,246,1196,1620,598,2668,2915
|
0.7152942406319166,3.6087693640312484,0.02167903874393584,-0.23368633339360326,0.6276115039211269,-0.02106529204966477,0.3012772815040069,-1.2882658134684348,0.2796623627116229,4.186646783930239,-0.14885918591010985,-0.7570132956764223,3.0861951345931513,-0.04241010240522003,-0.40244498209708657,-0.5073057591164345,0.4096172898409424,-0.04241010240522003,1.2247336356763627,-0.569993271061387,-0.2759883981888322,-0.942446145812876,1.359078200582899,1.0909822301776992,0.0002977667180233936,-0.36036802408587215,-0.36036802408587215,2.6172401968299104,1.5842880896557086,1.9708151956500113,-0.4654184907728244,0.6495063733352072,1.8338719570141517,-0.4234551139739826,0.6057338953933035,-0.12760615078476442,-0.4863716580376144,-0.9013775888027895,2.131292988821414,-0.736311113618571,1.0021471184507622,0.12885737883854684,-1.4889006936454316,0.19338072765197223,-0.4234551139739826,0.7372578479891295,-0.5073057591164345,0.7592385640896675,1.4039905186201218,0.2796623627116229,0.0002977667180233936,0.7812363588966038,-0.6325077598761806,-0.8602294627439812
| 3,430
|
Respirasome
| 19
| 45
| 2.556625
| 0.010569
|
O43676,P51970,Q6DKK2,P14927,O75306,Q16718,P20674,O00217,Q9P0J0,Q9UDW1,P14406,P00403,Q9Y6M9,Q86Y39,P08574,P22695,P13073,P14854,P03886
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
4,397,267,14,514,146,659,656,45,579,560,558,449,352,223,232,108,484,500
|
656,2858,1367,4,3021,2587,514,2369,1435,710,1514,3175,2060,1515,558,500,223,1663,1664,108,560,484,14,3211,3142,659,2332,232,2886,2483,1473,1713,3124,397,884,146,1180,267,2635,352,1092,45,579,1590,449
|
0.6933477721843095,-0.8190021137923701,0.15034720133396523,4.551842722059264,-0.9834347839005033,-0.5908507122210328,0.8693977289284917,-0.4654184907728244,0.10738556209941592,0.6276115039211269,0.06449608277835585,-1.2074277428722162,-0.2759883981888322,0.06449608277835585,0.8032512025014997,0.8914804711800896,1.448967877539575,-0.04241010240522003,-0.04241010240522003,2.0394981091593998,0.8032512025014997,0.9135801145844248,3.537101859755954,-1.2882658134684348,-1.1465830158056964,0.6933477721843095,-0.44444629644309747,1.4264710812485106,-0.8396256696385406,-0.5282207546911941,0.0859317852989234,-0.06373662902854216,-1.1059176287710073,1.0465312750378557,0.4966058497171867,1.8111031480459492,0.2796623627116229,1.314231136956651,-0.6116888886017858,1.1354997578192654,0.34456029993080256,2.7105571292304815,0.8032512025014997,0.02167903874393584,0.9799801607699364
| 3,430
|
Establishment of protein localization to membrane
| 20
| 89
| 2.555055
| 0.010617
|
Q01082,Q9NS69,P43307,Q8IWJ2,Q15041,O15118,Q15907,O00560,Q9P0J0,Q9UPN3,P07900,Q15006,O14737,Q9Y5J9,O60725,P0DP25,Q9HD20,Q96A33,Q13277,Q9Y5L4
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
256,7,132,263,266,265,159,154,45,321,314,189,206,84,86,338,227,238,111,114
|
1948,1874,154,206,2821,265,766,1231,86,2096,557,987,1436,314,1988,338,2166,1667,2519,1746,2593,714,1711,132,879,939,2776,691,2409,1796,3417,2103,2104,1579,3302,1884,1639,256,995,2491,1342,111,2679,189,266,1345,589,1558,2730,159,2344,2634,2415,1249,3117,263,2000,1604,1492,3000,2118,238,507,2124,1861,551,2932,2693,227,705,1615,7,2259,403,45,2263,870,1621,2618,3217,3298,321,1590,1655,819,843,1774,84,114
|
-0.21250736851480986,-0.17009375816547115,1.7656129496664057,1.5165554046538223,-0.7776958844485033,1.314231136956651,0.5838735785783277,0.23648587072936555,2.177283285595381,-0.2971114238181862,0.8032512025014997,0.4096172898409424,0.10738556209941592,1.2024003828056788,-0.23368633339360326,1.1577834161963467,-0.3393012744587857,-0.04241010240522003,-0.5491166052451673,-0.08504483643208101,-0.5908507122210328,0.6276115039211269,-0.06373662902854216,1.8794568708577217,0.4966058497171867,0.45307654705381356,-0.736311113618571,0.6495063733352072,-0.4863716580376144,-0.10633468895957496,-3.455511531066017,-0.2971114238181862,-0.2971114238181862,0.02167903874393584,-1.5685621747527327,-0.17009375816547115,-0.02106529204966477,1.359078200582899,0.4096172898409424,-0.5282207546911941,0.17185499556109507,2.0165882176348306,-0.6533072855099272,1.6068977874861423,1.314231136956651,0.17185499556109507,0.7812363588966038,0.04307848903912287,-0.6948481366740377,1.7656129496664057,-0.44444629644309747,-0.6116888886017858,-0.4863716580376144,0.23648587072936555,-1.085554403485646,1.3366464985559088,-0.23368633339360326,0.0002977667180233936,0.0859317852989234,-0.942446145812876,-0.2971114238181862,1.4264710812485106,0.8914804711800896,-0.2971114238181862,-0.14885918591010985,0.8252830651235218,-0.8808134501833325,-0.6533072855099272,1.448967877539575,0.6495063733352072,0.0002977667180233936,4.283733422464173,-0.38141593935161383,1.0465312750378557,2.7105571292304815,-0.38141593935161383,0.518396688704323,0.0002977667180233936,-0.5908507122210328,-1.2882658134684348,-1.548678875208257,1.2024003828056788,0.02167903874393584,-0.02106529204966477,0.5620305844376072,0.5402049440683143,-0.08504483643208101,2.2233352367607586,2.0165882176348306
| 3,430
|
Apoptosis
| 33
| 90
| 2.554916
| 0.010621
|
O43242,Q9UNM6,P08670,Q9Y3B8,Q92530,Q15149,P42574,Q04917,P51572,Q9NR28,P28070,P02545,P31946,P61981,P62191,P63104,Q13464,P48556,Q13177,P62258,Q9Y5V3,P17980,P49354,P20700,Q07021,Q15008,P61289,P62195,P09429,O00429,O00231,P26583,Q13813
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
375,269,11,278,538,416,533,284,410,552,41,46,178,427,184,316,430,445,195,67,599,454,203,77,217,470,213,214,465,600,356,621,119
|
356,2699,1573,600,1777,897,375,616,2401,46,2302,3341,11,465,3400,1957,3372,3368,454,1990,77,1992,902,2233,2434,621,677,1169,737,41,2199,3025,1439,1667,178,2829,1670,1790,2168,533,798,445,1553,203,2304,2065,410,940,3241,2377,1882,1635,213,427,184,214,67,2239,316,2991,284,1598,1026,217,2201,995,2175,195,772,430,1176,119,2993,1890,3383,470,416,721,538,3190,2836,1934,552,2877,2468,2192,1159,269,278,599
|
1.1132326864910351,-0.6740874247602239,0.02167903874393584,0.7592385640896675,-0.10633468895957496,0.4748324586170831,1.0687484169607406,0.7372578479891295,-0.4863716580376144,2.6872054940154664,-0.4234551139739826,-1.7465394682740971,3.824533083456319,0.9356966299859146,-2.6088832120872674,-0.21250736851480986,-1.9810691920969703,-1.9616481810876696,0.9578299883515244,-0.23368633339360326,2.3156233598343645,-0.23368633339360326,0.4748324586170831,-0.38141593935161383,-0.5073057591164345,0.7372578479891295,0.6714184729428473,0.2796623627116229,0.6057338953933035,2.8041124444238252,-0.36036802408587215,-0.9834347839005033,0.10738556209941592,-0.04241010240522003,1.6748229295823038,-0.7776958844485033,-0.04241010240522003,-0.10633468895957496,-0.3393012744587857,0.8473319171085857,0.5620305844376072,0.9799801607699364,0.04307848903912287,1.5391168723820783,-0.4234551139739826,-0.2759883981888322,1.0243308327237213,0.45307654705381356,-1.3687716700453372,-0.4654184907728244,-0.17009375816547115,-0.02106529204966477,1.4940100655111697,1.0021471184507622,1.65216523300499,1.4940100655111697,2.431327036159296,-0.38141593935161383,1.2024003828056788,-0.942446145812876,1.269449542990556,0.0002977667180233936,0.387914008197925,1.4940100655111697,-0.36036802408587215,0.4096172898409424,-0.3393012744587857,1.5842880896557086,0.5838735785783277,1.0021471184507622,0.2796623627116229,1.9708151956500113,-0.942446145812876,-0.17009375816547115,-2.1740240119418117,0.9356966299859146,1.0243308327237213,0.6276115039211269,0.8473319171085857,-1.227668237248389,-0.7776958844485033,-0.191309831206804,0.8252830651235218,-0.8190021137923701,-0.5073057591164345,-0.3393012744587857,0.3012772815040069,1.314231136956651,1.291832142745204,0.7812363588966038
| 3,430
|
Response to heat
| 11
| 44
| 2.551294
| 0.010732
|
O15514,Q58FF6,P62258,Q9H078,P09601,Q13535,O95391,P42345,P12270,P49770,P07900
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
163,196,67,333,71,292,70,233,107,367,314
|
163,1625,1289,1462,2432,70,1235,1707,314,404,71,1073,107,1632,1879,2973,1168,1669,233,1295,367,2138,680,882,67,1114,661,292,1212,1410,196,2458,3018,3085,2424,629,1765,333,2222,2506,2913,1621,2226,1734
|
1.742891610000047,-0.02106529204966477,0.19338072765197223,0.0859317852989234,-0.5073057591164345,2.40815588672373,0.23648587072936555,-0.06373662902854216,1.2024003828056788,1.0243308327237213,2.40815588672373,0.34456029993080256,2.0394981091593998,-0.02106529204966477,-0.17009375816547115,-0.9219218352181526,0.2796623627116229,-0.04241010240522003,1.4264710812485106,0.19338072765197223,1.0909822301776992,-0.31821572844136564,0.6714184729428473,0.4966058497171867,2.431327036159296,0.3229099381780773,0.6933477721843095,1.2470833648713042,0.2580652147528089,0.12885737883854684,1.5842880896557086,-0.5073057591164345,-0.9629504767360699,-1.0447671183808418,-0.4863716580376144,0.7372578479891295,-0.08504483643208101,1.1800836337709497,-0.36036802408587215,-0.5282207546911941,-0.8602294627439812,0.0002977667180233936,-0.36036802408587215,-0.06373662902854216
| 3,430
|
Myometrial relaxation and contraction pathways
| 11
| 26
| 2.527157
| 0.011499
|
Q04917,P16615,P62258,Q05682,Q9Y3B8,P31946,P61981,P05771,P0DP25,O43665,P63104
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
284,602,67,204,278,178,427,584,338,54,316
|
54,584,338,1236,1074,602,877,1632,1879,2061,677,178,2828,427,67,2307,316,1444,1269,284,1598,204,2071,2280,3304,278
|
2.5706715559059043,0.7812363588966038,1.1577834161963467,0.23648587072936555,0.34456029993080256,0.7592385640896675,0.4966058497171867,-0.02106529204966477,-0.17009375816547115,-0.2759883981888322,0.6714184729428473,1.6748229295823038,-0.7776958844485033,1.0021471184507622,2.431327036159296,-0.4234551139739826,1.2024003828056788,0.10738556209941592,0.21492436389411237,1.269449542990556,0.0002977667180233936,1.5391168723820783,-0.2759883981888322,-0.40244498209708657,-1.5685621747527327,1.291832142745204
| 3,430
|
Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand
| 20
| 31
| 2.521609
| 0.011682
|
P61163,Q13451,Q9Y6G9,Q13561,P11142,P25685,P08238,P54652,P31948,Q15185,P52907,O75935,Q14203,P07900,Q14204,O43237,P0DMV9,P04350,P47755,Q02790
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
1141,398,1067,415,1165,1168,404,680,290,943,301,443,188,314,833,311,1073,1132,991,368
|
311,1625,443,1132,314,404,1073,1165,1168,1669,290,991,1672,301,680,1141,2991,2139,368,1406,398,415,1581,188,833,943,1220,2083,2360,2091,1067
|
1.2024003828056788,-0.02106529204966477,0.9799801607699364,0.3012772815040069,1.2024003828056788,1.0243308327237213,0.34456029993080256,0.2796623627116229,0.2796623627116229,-0.04241010240522003,1.2470833648713042,0.4096172898409424,-0.04241010240522003,1.2247336356763627,0.6714184729428473,0.3012772815040069,-0.942446145812876,-0.31821572844136564,1.0909822301776992,0.12885737883854684,1.0465312750378557,1.0243308327237213,0.02167903874393584,1.6068977874861423,0.5402049440683143,0.45307654705381356,0.2580652147528089,-0.2759883981888322,-0.44444629644309747,-0.2759883981888322,0.3662283341069291
| 3,430
|
Cristae formation
| 10
| 19
| 2.521508
| 0.011685
|
O75964,P48047,P06576,Q16891,P24539,Q9NX63,P36542,P25705,O75431,P56385
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
2,521,40,360,109,578,281,501,219,412
|
219,793,2,40,109,501,281,1814,521,3294,412,588,360,2755,1999,3129,1319,578,819
|
1.4714808810674698,0.5620305844376072,5.167196520160504,2.8041124444238252,2.0394981091593998,0.8914804711800896,1.269449542990556,-0.12760615078476442,0.8693977289284917,-1.548678875208257,1.0243308327237213,0.7812363588966038,1.1132326864910351,-0.7155893800863863,-0.23368633339360326,-1.1059176287710073,0.19338072765197223,0.8032512025014997,0.5620305844376072
| 3,430
|
Subsets and Splits
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