term
stringlengths 2
121
| overlap
int64 6
281
| setsize
int64 7
499
| score
float64 1.96
10.6
| pval
float64 0
0.05
| edge
stringlengths 41
1.97k
| type
stringclasses 5
values | subtype
stringclasses 24
values | subtype_key
stringclasses 24
values | edge_idxs
stringlengths 11
1.17k
| ann_idxs
stringlengths 19
2.31k
| ann_vals
stringlengths 124
9.94k
| sig_size
int64 2.2k
3.73k
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Proton transmembrane transporter activity
| 14
| 31
| 2.671959
| 0.007541
|
P13073,Q9UDW1,Q13423,P12235,P47985,O75964,P00403,P05141,P25705,Q9Y487,P06576,O95202,Q93050,P24539
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
167,40,71,447,484,45,145,553,244,215,435,123,92,411
|
1938,45,123,145,553,435,970,1872,447,167,1797,1537,2377,411,244,3038,2318,1539,2976,484,3321,1073,1127,746,1548,71,92,2636,40,585,215
|
-0.25557908848123395,3.286174597616811,2.19713106377011,2.002235460610414,0.5636060512556167,0.7348993205919421,0.1999552233330087,-0.22570012371921228,0.7108269558541094,1.7795540517583925,-0.19602066046695343,-0.07924492702588042,-0.43919996831517205,0.7826588994764823,1.3192668476331657,-0.8997389788237078,-0.40806438662984673,-0.07924492702588042,-0.8309434988946349,0.6622900003005412,-1.5724386516725661,0.14549770029311399,0.11801732694304702,0.3594471701790773,-0.07924492702588042,2.9465065973455364,2.5793442451134623,-0.5659738392609449,3.380645404831543,0.5385907773537494,1.525203768425511
| 3,367
|
Membrane microdomain
| 15
| 67
| 2.660704
| 0.007798
|
P09601,O75955,P35613,O14773,P09104,P41440,P05067,P21796,P27105,P13473,O15118,P25705,P50897,Q8WTV0,P19022
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
0,162,165,70,327,186,90,13,124,210,85,244,26,60,286
|
1275,495,2363,70,85,3115,162,2023,3032,3261,1870,610,90,553,1531,3236,2370,2025,2105,327,0,1176,692,210,1796,973,1346,286,2655,436,773,13,2601,244,124,2763,2431,638,1185,742,2841,165,1288,186,2434,743,2321,26,2325,3178,1890,2613,1078,1304,858,338,598,828,60,3078,3280,678,2800,1579,2833,1159,527
|
0.034544176031171075,0.6378225083090472,-0.43919996831517205,2.9465065973455364,2.7359582136753127,-1.004980242603473,1.8550102756937976,-0.28566029525923553,-0.8997389788237078,-1.298525940794424,-0.22570012371921228,0.488136037900703,2.595251590463738,0.5636060512556167,-0.07924492702588042,-1.1861480785988963,-0.43919996831517205,-0.28566029525923553,-0.31594654169938047,0.9914868411153721,5.77073025593568,0.09036639678564706,0.41136873678446767,1.5452878774447738,-0.19602066046695343,0.1999552233330087,0.0063684354015670136,1.1254866370979533,-0.5982416058990344,0.7348993205919421,0.3332580754721944,4.220028343416946,-0.5659738392609449,1.3192668476331657,2.19713106377011,-0.6634903102109926,-0.4705554931571856,0.46269330605308917,0.09036639678564706,0.3594471701790773,-0.7297139540963061,1.7985369233817154,0.034544176031171075,1.6639450277501382,-0.4705554931571856,0.3594471701790773,-0.40806438662984673,3.6904275097045454,-0.40806438662984673,-1.0765587039609845,-0.22570012371921228,-0.5659738392609449,0.14549770029311399,0.034544176031171075,0.2804141068248859,0.9687588066338071,0.5134346459158582,0.30691434248850596,3.1896999455248927,-0.9345419567612725,-1.3366301135330916,0.4371047742428398,-0.6634903102109926,-0.07924492702588042,-0.6964784202356398,0.11801732694304702,0.6132203653820887
| 3,367
|
Rough endoplasmic reticulum
| 9
| 33
| 2.659954
| 0.007815
|
Q07065,P04843,Q5BJF2,Q8TCT9,Q99442,Q9UQB8,Q9Y5M8,P05067,Q15041
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
131,254,7,202,176,86,120,90,223
|
2093,1526,2101,254,1173,90,2600,2656,556,639,1237,897,3286,3222,2259,1807,852,1295,1738,3322,854,1812,1475,131,223,7,1429,202,274,176,766,86,120
|
-0.31594654169938047,-0.07924492702588042,-0.31594654169938047,1.2555985905367433,0.09036639678564706,2.595251590463738,-0.5659738392609449,-0.5982416058990344,0.5636060512556167,0.46269330605308917,0.06254274771127205,0.2537554699892711,-1.37506621536203,-1.1493154316371736,-0.37714563952921315,-0.19602066046695343,0.2804141068248859,0.034544176031171075,-0.16653801380920247,-1.5724386516725661,0.2804141068248859,-0.19602066046695343,-0.05052375805598644,2.144806762718082,1.4644074828289309,4.552178889851971,-0.02198676428679048,1.5851890116525102,1.1692778855749448,1.722120594018782,0.3594471701790773,2.7050655515155833,2.2316801472635333
| 3,367
|
Sphingolipid metabolism
| 6
| 9
| 2.65604
| 0.007906
|
O15269,P07602,P17900,Q06136,Q13510,P04062
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
220,65,169,77,78,118
|
220,965,250,118,65,169,77,78,685
|
1.4644074828289309,0.1999552233330087,1.276921824455599,2.248856101291637,3.0911332595741183,1.7413465847323417,2.8724277004854066,2.8724277004854066,0.4371047742428398
| 3,367
|
Supranuclear gaze palsy
| 8
| 20
| 2.654158
| 0.007951
|
P07602,Q96RL7,P61916,Q9NZJ7,O15118,P04062,Q99720,P35637
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
65,297,197,276,85,118,28,192
|
2707,1276,85,118,65,2810,2975,192,2818,197,2501,1553,468,1092,297,1094,28,276,1519,369
|
-0.6307459142786708,0.034544176031171075,2.7359582136753127,2.248856101291637,3.0911332595741183,-0.6964784202356398,-0.8309434988946349,1.6247393272059847,-0.6964784202356398,1.605007630123358,-0.5021341373910327,-0.07924492702588042,0.6866243286062695,0.14549770029311399,1.1034296234289172,0.14549770029311399,3.665401627508389,1.1692778855749448,-0.05052375805598644,0.8998745416649946
| 3,367
|
Polyneuropathy
| 10
| 18
| 2.653119
| 0.007975
|
P07602,O95831,Q9HC21,P60891,Q9NZJ7,O60313,P04066,Q8N2K0,O95721,Q15041
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
65,35,324,450,276,279,184,419,247,223
|
279,247,35,184,65,1399,3038,1666,450,518,223,618,1253,419,760,324,276,2801
|
1.1474357022138544,1.2981442560194676,3.512290521765781,1.6639450277501382,3.0911332595741183,-0.02198676428679048,-0.8997389788237078,-0.1372495529245524,0.7108269558541094,0.6132203653820887,1.4644074828289309,0.488136037900703,0.06254274771127205,0.7826588994764823,0.3594471701790773,1.014100175743301,1.1692778855749448,-0.6634903102109926
| 3,367
|
Apical part of cell
| 23
| 51
| 2.649168
| 0.008069
|
Q99808,Q13131,Q86UE4,P19022,O75955,Q8NCM8,P35241,Q9Y4G8,Q15043,P20020,P41440,P11166,Q14254,P30825,P05067,P53985,P08183,Q15154,P26038,Q16625,P05023,Q99538,P35222
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
259,519,153,286,162,537,657,564,293,436,186,692,338,89,90,103,110,362,611,242,610,507,742
|
1855,2363,1391,924,162,2480,2484,610,90,110,807,1723,1065,692,3011,973,286,436,1537,2377,611,89,742,657,1539,2187,2976,186,103,1126,2322,1606,746,819,519,2943,857,338,293,362,1309,242,153,537,507,259,1218,1268,2084,564,2536
|
-0.22570012371921228,-0.43919996831517205,-0.02198676428679048,0.22693649856222178,1.8550102756937976,-0.5021341373910327,-0.5021341373910327,0.488136037900703,2.595251590463738,2.2999956417932186,0.30691434248850596,-0.16653801380920247,0.14549770029311399,0.41136873678446767,-0.8652075817496219,0.1999552233330087,1.1254866370979533,0.7348993205919421,-0.07924492702588042,-0.43919996831517205,0.488136037900703,2.6583280208911844,0.3594471701790773,0.4371047742428398,-0.07924492702588042,-0.34644068419145774,-0.8309434988946349,1.6639450277501382,2.40057096317167,0.11801732694304702,-0.40806438662984673,-0.10815269963874782,0.3594471701790773,0.30691434248850596,0.6132203653820887,-0.7969425638483784,0.2804141068248859,0.9687588066338071,1.1034296234289172,0.8998745416649946,0.034544176031171075,1.3402905479186136,1.9840930614703445,0.588482059091134,0.6378225083090472,1.2555985905367433,0.09036639678564706,0.06254274771127205,-0.28566029525923553,0.5636060512556167,-0.5021341373910327
| 3,367
|
Neuron apoptotic process
| 10
| 50
| 2.646435
| 0.008135
|
P09601,O95831,Q92542,P05067,Q96A26,Q01105,Q9NR28,P04062,P50897,Q99720
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
0,35,227,90,175,181,213,118,26,28
|
3064,1648,1279,609,393,804,35,118,3255,2713,928,90,1532,1795,1065,0,2374,1534,257,742,2434,2891,659,2934,1666,1465,2256,743,2555,26,2037,2556,1606,2770,3306,181,1416,615,718,227,1092,175,3134,3280,507,28,762,213,960,1164
|
-0.9345419567612725,-0.1372495529245524,0.034544176031171075,0.488136037900703,0.8299141117114622,0.30691434248850596,3.512290521765781,2.248856101291637,-1.2607479309781038,-0.6307459142786708,0.22693649856222178,2.595251590463738,-0.07924492702588042,-0.19602066046695343,0.14549770029311399,5.77073025593568,-0.43919996831517205,-0.07924492702588042,1.2555985905367433,0.3594471701790773,-0.4705554931571856,-0.7632007073119792,0.4371047742428398,-0.7969425638483784,-0.1372495529245524,-0.05052375805598644,-0.37714563952921315,0.3594471701790773,-0.5339391468977894,3.6904275097045454,-0.28566029525923553,-0.5339391468977894,-0.10815269963874782,-0.6634903102109926,-1.4924261166507573,1.7028121530513547,-0.02198676428679048,0.488136037900703,0.3854834577363446,1.443957948969997,0.14549770029311399,1.722120594018782,-1.004980242603473,-1.3366301135330916,0.6378225083090472,3.665401627508389,0.3594471701790773,1.525203768425511,0.22693649856222178,0.11801732694304702
| 3,367
|
Inner mitochondrial membrane protein complex
| 24
| 69
| 2.639766
| 0.008296
|
O43676,O60830,Q99595,P00403,Q8IYU8,P24539,P13073,Q9UDW1,O75964,P06576,P12236,Q13505,Q9NX63,Q86Y39,O14925,O75431,Q9P0J0,Q9BUR5,P47985,P22695,Q16891,P25705,Q5XKP0,P14406
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
4,9,11,145,534,411,167,40,45,435,307,58,461,340,464,97,230,367,484,482,363,244,502,252
|
3313,1389,464,4,9,2096,1057,97,2242,1938,45,2243,3233,2969,2024,145,435,970,1066,1872,307,167,252,2376,3192,1797,2430,482,411,244,3173,2604,3038,2031,2318,3220,484,3321,3095,661,1073,1127,58,2506,2336,363,826,698,502,784,340,534,1493,834,705,11,1507,1376,367,2797,878,2156,461,230,40,733,734,565,1110
|
-1.5322507832020744,-0.02198676428679048,0.6866243286062695,4.744465578955981,4.521067264147013,-0.31594654169938047,0.14549770029311399,2.4171181472402936,-0.37714563952921315,-0.25557908848123395,3.286174597616811,-0.37714563952921315,-1.1861480785988963,-0.8309434988946349,-0.28566029525923553,2.002235460610414,0.7348993205919421,0.1999552233330087,0.14549770029311399,-0.22570012371921228,1.058987402257529,1.7795540517583925,1.276921824455599,-0.43919996831517205,-1.112787329154505,-0.19602066046695343,-0.4705554931571856,0.6622900003005412,0.7826588994764823,1.3192668476331657,-1.0765587039609845,-0.5659738392609449,-0.8997389788237078,-0.28566029525923553,-0.40806438662984673,-1.1493154316371736,0.6622900003005412,-1.5724386516725661,-0.969620885690122,0.4371047742428398,0.14549770029311399,0.11801732694304702,3.2036080031326675,-0.5021341373910327,-0.40806438662984673,0.8998745416649946,0.30691434248850596,0.41136873678446767,0.6378225083090472,0.3332580754721944,0.9687588066338071,0.588482059091134,-0.05052375805598644,0.30691434248850596,0.41136873678446767,4.253245556056843,-0.05052375805598644,0.0063684354015670136,0.8998745416649946,-0.6634903102109926,0.2804141068248859,-0.31594654169938047,0.7108269558541094,1.4234149403548129,3.380645404831543,0.3854834577363446,0.3854834577363446,0.5636060512556167,0.14549770029311399
| 3,367
|
Abnormal conjunctiva morphology
| 9
| 29
| 2.632187
| 0.008484
|
P10619,P28070,Q9NZ08,P02786,Q14739,P06280,Q13510,P04066,O00462
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
190,36,168,200,266,139,78,184,126
|
126,1591,302,200,184,3087,139,190,2108,1286,975,2430,2248,36,3150,848,743,2978,1124,1743,3290,78,266,1307,425,1501,1318,1154,168
|
2.1797569087503486,-0.10815269963874782,1.081263578277897,1.5851890116525102,1.6639450277501382,-0.969620885690122,2.074084118777206,1.6247393272059847,-0.31594654169938047,0.034544176031171075,0.1999552233330087,-0.4705554931571856,-0.37714563952921315,3.473195069920084,-1.0406246148817728,0.2804141068248859,0.3594471701790773,-0.8309434988946349,0.11801732694304702,-0.16653801380920247,-1.4138401674883982,2.8724277004854066,1.2126457954814382,0.034544176031171075,0.7588428378146155,-0.05052375805598644,0.034544176031171075,0.11801732694304702,1.7795540517583925
| 3,367
|
Transition metal ion homeostasis
| 8
| 24
| 2.619535
| 0.008805
|
P09601,P30519,Q658P3,P02786,Q15904,Q8N511,Q9Y487,P05067
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
0,1,129,200,173,48,215,90
|
2171,1452,654,593,1015,568,3253,200,3255,90,0,774,1,2491,2976,746,3290,2042,293,173,129,48,1512,215
|
-0.34644068419145774,-0.05052375805598644,0.4371047742428398,0.5134346459158582,0.17280963840827135,0.5385907773537494,-1.2607479309781038,1.5851890116525102,-1.2607479309781038,2.595251590463738,5.77073025593568,0.3332580754721944,5.215090048676801,-0.5021341373910327,-0.8309434988946349,0.3594471701790773,-1.4138401674883982,-0.28566029525923553,1.1034296234289172,1.722120594018782,2.16231565108635,3.286174597616811,-0.05052375805598644,1.525203768425511
| 3,367
|
Abnormal biliary tract morphology
| 10
| 25
| 2.618957
| 0.00882
|
P09601,P07602,O43933,Q14108,Q14739,Q10713,Q9NZJ7,Q9NSD9,P04062,Q5XKP0
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
0,65,132,5,266,398,276,474,118,502
|
738,132,805,118,65,0,893,555,3302,849,1666,1292,398,696,5,266,502,1501,1983,726,474,276,1930,733,2474
|
0.3594471701790773,2.12722970929693,0.30691434248850596,2.248856101291637,3.0911332595741183,5.77073025593568,0.2537554699892711,0.5636060512556167,-1.4924261166507573,0.2804141068248859,-0.1372495529245524,0.034544176031171075,0.8299141117114622,0.41136873678446767,4.744465578955981,1.2126457954814382,0.6378225083090472,-0.05052375805598644,-0.25557908848123395,0.3854834577363446,0.6866243286062695,1.1692778855749448,-0.22570012371921228,0.3854834577363446,-0.4705554931571856
| 3,367
|
Active transmembrane transporter activity
| 21
| 59
| 2.617895
| 0.008847
|
O43676,P51798,P00403,Q9UBX3,P13073,Q15043,Q9UDW1,P16615,P05141,P20020,P06576,P12236,P41440,P12235,Q9P0J0,P53985,P47985,P08183,Q9HD20,P28288,O95202
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
4,516,145,18,167,293,40,290,553,436,435,307,186,447,230,103,484,110,115,372,123
|
3313,1389,1588,4,1015,2096,1057,2242,2243,3233,123,2969,2024,145,610,553,435,110,807,970,1872,447,307,167,290,3192,436,1797,1537,2377,372,3173,3038,1539,2976,186,484,3095,516,661,1071,103,2322,746,1548,980,293,906,2506,2336,1493,2636,115,1710,230,18,40,585,1110
|
-1.5322507832020744,-0.02198676428679048,-0.10815269963874782,4.744465578955981,0.17280963840827135,-0.31594654169938047,0.14549770029311399,-0.37714563952921315,-0.37714563952921315,-1.1861480785988963,2.19713106377011,-0.8309434988946349,-0.28566029525923553,2.002235460610414,0.488136037900703,0.5636060512556167,0.7348993205919421,2.2999956417932186,0.30691434248850596,0.1999552233330087,-0.22570012371921228,0.7108269558541094,1.058987402257529,1.7795540517583925,1.1034296234289172,-1.112787329154505,0.7348993205919421,-0.19602066046695343,-0.07924492702588042,-0.43919996831517205,0.8766756507402944,-1.0765587039609845,-0.8997389788237078,-0.07924492702588042,-0.8309434988946349,1.6639450277501382,0.6622900003005412,-0.969620885690122,0.6132203653820887,0.4371047742428398,0.14549770029311399,2.40057096317167,-0.40806438662984673,0.3594471701790773,-0.07924492702588042,0.1999552233330087,1.1034296234289172,0.2537554699892711,-0.5021341373910327,-0.40806438662984673,-0.05052375805598644,-0.5659738392609449,2.283013353361886,-0.1372495529245524,1.4234149403548129,4.015494309311654,3.380645404831543,0.5385907773537494,0.14549770029311399
| 3,367
|
Secondary active transmembrane transporter activity
| 8
| 17
| 2.617468
| 0.008858
|
P53985,Q15043,P12235,P51798,Q9UBX3,P12236,P41440,O95202
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
103,293,447,516,18,307,186,123
|
123,553,807,447,307,186,516,1071,103,2322,1548,980,293,906,1493,2636,18
|
2.19713106377011,0.5636060512556167,0.30691434248850596,0.7108269558541094,1.058987402257529,1.6639450277501382,0.6132203653820887,0.14549770029311399,2.40057096317167,-0.40806438662984673,-0.07924492702588042,0.1999552233330087,1.1034296234289172,0.2537554699892711,-0.05052375805598644,-0.5659738392609449,4.015494309311654
| 3,367
|
Agitation
| 12
| 33
| 2.609723
| 0.009062
|
P42858,Q14203,P48449,Q15165,P42892,P52732,P04062,P35610,P05067,Q92804,O96008,P35637
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
344,468,98,135,43,304,118,308,90,219,466,192
|
1527,926,466,118,90,2309,1657,1176,2882,308,192,344,43,1186,98,976,2037,304,2818,518,1191,2501,1553,468,1134,135,1487,1753,1976,219,1209,3280,3026
|
-0.07924492702588042,0.22693649856222178,0.6866243286062695,2.248856101291637,2.595251590463738,-0.40806438662984673,-0.1372495529245524,0.09036639678564706,-0.7632007073119792,1.058987402257529,1.6247393272059847,0.9459148854023514,3.34039786005235,0.09036639678564706,2.4171181472402936,0.1999552233330087,-0.28566029525923553,1.081263578277897,-0.6964784202356398,0.6132203653820887,0.09036639678564706,-0.5021341373910327,-0.07924492702588042,0.6866243286062695,0.11801732694304702,2.0918689378538042,-0.05052375805598644,-0.16653801380920247,-0.25557908848123395,1.4847644010892234,0.09036639678564706,-1.3366301135330916,-0.8652075817496219
| 3,367
|
Coated vesicle membrane
| 15
| 53
| 2.606637
| 0.009144
|
P24390,Q13190,P11717,Q14108,P02786,Q9Y3B3,P10321,P01889,P49755,Q8N511,P09496,P04439,P20645,Q9Y678,P35606
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
2,355,217,5,200,75,481,302,437,48,554,333,185,391,497
|
2171,1225,3347,801,1653,691,2544,2367,1281,1230,1170,1282,1062,302,200,333,554,1594,481,1940,217,773,185,2,497,1949,572,437,2723,1670,813,2258,2896,1737,1956,817,355,5,2202,1360,1556,1307,48,835,795,2001,2468,2469,2748,1520,75,391,1586
|
-0.34644068419145774,0.06254274771127205,-1.8215870556151397,0.30691434248850596,-0.1372495529245524,0.41136873678446767,-0.5339391468977894,-0.43919996831517205,0.034544176031171075,0.06254274771127205,0.09036639678564706,0.034544176031171075,0.14549770029311399,1.081263578277897,1.5851890116525102,0.9687588066338071,0.5636060512556167,-0.10815269963874782,0.6622900003005412,-0.25557908848123395,1.5050295510613063,0.3332580754721944,1.6639450277501382,5.106453588871854,0.6378225083090472,-0.25557908848123395,0.5385907773537494,0.7348993205919421,-0.6307459142786708,-0.1372495529245524,0.30691434248850596,-0.37714563952921315,-0.7632007073119792,-0.16653801380920247,-0.25557908848123395,0.30691434248850596,0.9229538719151944,4.744465578955981,-0.34644068419145774,0.0063684354015670136,-0.07924492702588042,0.034544176031171075,3.286174597616811,0.30691434248850596,0.3332580754721944,-0.25557908848123395,-0.4705554931571856,-0.4705554931571856,-0.6307459142786708,-0.05052375805598644,2.9317872528718985,0.8533559354124849,-0.07924492702588042
| 3,367
|
Regulation of lipid metabolic process
| 20
| 53
| 2.605906
| 0.009163
|
P31751,Q13131,Q9NZJ7,Q2T9J0,Q8WTV0,P30536,Q9UBM7,P07602,Q96G23,P61916,Q6IAA8,Q13510,P34913,P16435,Q96N66,P50416,Q15120,Q92604,P42345,O75844
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
257,519,276,439,60,191,325,65,66,197,598,78,207,222,101,485,618,245,498,127
|
3318,1788,2543,1790,127,3145,2023,1171,2102,2484,610,65,1067,222,1346,191,257,207,2433,498,1466,485,3304,1606,197,2441,981,2396,519,78,1421,2043,2727,618,1245,439,2822,598,1367,1911,60,245,2143,66,101,1210,1507,276,325,2162,1450,1579,3312
|
-1.5724386516725661,-0.19602066046695343,-0.5339391468977894,-0.19602066046695343,2.16231565108635,-1.0406246148817728,-0.28566029525923553,0.09036639678564706,-0.31594654169938047,-0.5021341373910327,0.488136037900703,3.0911332595741183,0.14549770029311399,1.4644074828289309,0.0063684354015670136,1.6247393272059847,1.2555985905367433,1.5652826911718993,-0.4705554931571856,0.6378225083090472,-0.05052375805598644,0.6622900003005412,-1.4924261166507573,-0.10815269963874782,1.605007630123358,-0.4705554931571856,0.1999552233330087,-0.43919996831517205,0.6132203653820887,2.8724277004854066,-0.02198676428679048,-0.28566029525923553,-0.6307459142786708,0.488136037900703,0.06254274771127205,0.7348993205919421,-0.6964784202356398,0.5134346459158582,0.0063684354015670136,-0.22570012371921228,3.1896999455248927,1.3192668476331657,-0.31594654169938047,3.0911332595741183,2.4171181472402936,0.09036639678564706,-0.05052375805598644,1.1692778855749448,1.014100175743301,-0.31594654169938047,-0.02198676428679048,-0.07924492702588042,-1.4924261166507573
| 3,367
|
Phospholipid binding
| 9
| 96
| 2.596599
| 0.009415
|
P07602,Q14108,P21796,Q9UM22,P45880,P50897,Q8WTV0,Q9Y5X1,Q8NCC3
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
65,5,13,14,19,26,60,30,63
|
589,2425,1225,735,495,70,392,1391,2018,924,279,3282,465,1227,2484,2370,65,2309,1655,1656,2653,1940,1658,929,13,2314,3151,2814,2382,19,2494,779,2435,26,976,979,2437,1547,518,695,1300,1078,820,2042,1242,2446,5,2202,988,3224,361,1360,2678,577,2053,2737,911,1627,63,913,60,1257,1497,2142,3346,3109,2692,1508,2693,1378,491,1327,1213,761,289,1214,1330,877,2912,276,880,2294,2998,1579,547,1847,14,2870,1159,960,511,2966,1932,564,30,567
|
0.5134346459158582,-0.4705554931571856,0.06254274771127205,0.3594471701790773,0.6378225083090472,2.9465065973455364,0.8299141117114622,-0.02198676428679048,-0.28566029525923553,0.22693649856222178,1.1474357022138544,-1.37506621536203,0.6866243286062695,0.06254274771127205,-0.5021341373910327,-0.43919996831517205,3.0911332595741183,-0.40806438662984673,-0.1372495529245524,-0.1372495529245524,-0.5982416058990344,-0.25557908848123395,-0.1372495529245524,0.22693649856222178,4.220028343416946,-0.40806438662984673,-1.0406246148817728,-0.6964784202356398,-0.43919996831517205,3.9215673900004977,-0.5021341373910327,0.3332580754721944,-0.4705554931571856,3.6904275097045454,0.1999552233330087,0.1999552233330087,-0.4705554931571856,-0.07924492702588042,0.6132203653820887,0.41136873678446767,0.034544176031171075,0.14549770029311399,0.30691434248850596,-0.28566029525923553,0.06254274771127205,-0.4705554931571856,4.744465578955981,-0.34644068419145774,0.1999552233330087,-1.1493154316371736,0.8998745416649946,0.0063684354015670136,-0.5982416058990344,0.5385907773537494,-0.28566029525923553,-0.6307459142786708,0.2537554699892711,-0.10815269963874782,3.1336381893089387,0.2537554699892711,3.1896999455248927,0.06254274771127205,-0.05052375805598644,-0.31594654169938047,-1.7790704476183576,-0.969620885690122,-0.5982416058990344,-0.05052375805598644,-0.5982416058990344,0.0063684354015670136,0.6622900003005412,0.034544176031171075,0.09036639678564706,0.3594471701790773,1.1254866370979533,0.09036639678564706,0.034544176031171075,0.2804141068248859,-0.7632007073119792,1.1692778855749448,0.2804141068248859,-0.37714563952921315,-0.8309434988946349,-0.07924492702588042,0.588482059091134,-0.19602066046695343,4.1865682400285555,-0.7297139540963061,0.11801732694304702,0.22693649856222178,0.6378225083090472,-0.7969425638483784,-0.22570012371921228,0.5636060512556167,3.614933961940769,0.5636060512556167
| 3,367
|
Cherry red spot of the macula
| 6
| 9
| 2.591877
| 0.009545
|
P10619,P07602,P16278,P17900,Q13510,P06865
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
190,65,41,169,78,81
|
81,65,1064,190,2758,41,169,78,276
|
2.781905953857426,3.0911332595741183,0.14549770029311399,1.6247393272059847,-0.6634903102109926,3.367269068562799,1.7413465847323417,2.8724277004854066,1.1692778855749448
| 3,367
|
Spectrin repeat [IPR002017]
| 7
| 10
| 2.590994
| 0.00957
|
Q9UPN3,P46939,O43707,P12814,Q13813,Q8WXH0,Q03001
|
Sequence
|
InterPro Repeat
|
interpro_repeat
|
494,413,410,448,292,331,423
|
1391,410,1397,448,413,518,423,292,331,494
|
-0.02198676428679048,0.7826588994764823,-0.02198676428679048,0.7108269558541094,0.7826588994764823,0.6132203653820887,0.7588428378146155,1.1034296234289172,0.9914868411153721,0.6622900003005412
| 3,367
|
Protein localization to mitochondrion
| 21
| 52
| 2.589026
| 0.009625
|
Q9NS69,O60830,O43615,Q99595,Q10713,Q13131,P51572,O14737,O95831,Q9Y512,O00429,Q9Y6C9,P30536,P49840,P55786,O96008,O14925,Q9P0J0,Q15070,Q9NX47,Q5JRX3
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
3,9,513,11,398,519,273,284,35,565,300,306,191,320,84,466,464,230,360,510,375
|
1854,2171,300,284,464,513,9,2595,2649,3254,2305,2369,35,466,969,3034,971,2655,2759,1234,191,2379,2432,572,320,273,1605,84,2846,398,519,360,3045,826,698,375,2344,1090,1506,11,3056,2797,3,510,230,2746,733,3299,1386,565,1853,306
|
-0.22570012371921228,-0.34644068419145774,1.081263578277897,1.1254866370979533,0.6866243286062695,0.6132203653820887,4.521067264147013,-0.5659738392609449,-0.5982416058990344,-1.2607479309781038,-0.40806438662984673,-0.43919996831517205,3.512290521765781,0.6866243286062695,0.1999552233330087,-0.8997389788237078,0.1999552233330087,-0.5982416058990344,-0.6634903102109926,0.06254274771127205,1.6247393272059847,-0.43919996831517205,-0.4705554931571856,0.5385907773537494,1.014100175743301,1.1692778855749448,-0.10815269963874782,2.7513259355917703,-0.7297139540963061,0.8299141117114622,0.6132203653820887,0.8998745416649946,-0.8997389788237078,0.30691434248850596,0.41136873678446767,0.8766756507402944,-0.40806438662984673,0.14549770029311399,-0.05052375805598644,4.253245556056843,-0.8997389788237078,-0.6634903102109926,4.832811783410612,0.6378225083090472,1.4234149403548129,-0.6307459142786708,0.3854834577363446,-1.45295805178107,0.0063684354015670136,0.5636060512556167,-0.19602066046695343,1.081263578277897
| 3,367
|
Monooxygenase activity
| 6
| 9
| 2.587898
| 0.009656
|
P09601,P30519,Q6UW02,Q15800,Q9BU89,Q16850
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
0,1,226,69,157,94
|
2098,0,1,814,339,69,94,226,157
|
-0.31594654169938047,5.77073025593568,5.215090048676801,0.30691434248850596,0.9687588066338071,2.9611783576004687,2.482708122078919,1.443957948969997,1.9475878367392199
| 3,367
|
EF-hand domain pair [IPR011992]
| 16
| 47
| 2.583625
| 0.009777
|
P46939,Q9UPN3,O43707,O43852,O75746,O75071,P12814,Q13813,Q03001,Q02818,P80303,Q9BRK5,Q9Y680,Q9UJS0,Q14257,O95202
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
413,494,410,196,381,68,448,292,423,46,15,148,178,546,151,123
|
410,196,68,2544,381,123,2485,2549,448,2838,972,1346,1181,2601,2491,2887,810,778,413,2897,15,46,423,292,151,2945,1361,1898,599,1314,2573,2056,534,946,1367,2408,916,3078,1376,148,649,1042,881,2469,546,494,178
|
0.7826588994764823,1.605007630123358,2.975802844788199,-0.5339391468977894,0.8533559354124849,2.19713106377011,-0.5021341373910327,-0.5339391468977894,0.7108269558541094,-0.7297139540963061,0.1999552233330087,0.0063684354015670136,0.09036639678564706,-0.5659738392609449,-0.5021341373910327,-0.7632007073119792,0.30691434248850596,0.3332580754721944,0.7826588994764823,-0.7632007073119792,4.164124775027304,3.286174597616811,0.7588428378146155,1.1034296234289172,1.9840930614703445,-0.7969425638483784,0.0063684354015670136,-0.22570012371921228,0.5134346459158582,0.034544176031171075,-0.5339391468977894,-0.28566029525923553,0.588482059091134,0.22693649856222178,0.0063684354015670136,-0.43919996831517205,0.2537554699892711,-0.9345419567612725,0.0063684354015670136,2.002235460610414,0.46269330605308917,0.17280963840827135,0.2804141068248859,-0.4705554931571856,0.588482059091134,0.6622900003005412,1.722120594018782
| 3,367
|
Abnormal epiphyseal ossification
| 9
| 17
| 2.579613
| 0.009891
|
Q9UBM7,O43933,P38435,O75381,Q15125,Q14739,Q96HY6,Q96L58,Q2M1P5
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
325,132,383,319,166,266,342,378,253
|
713,132,2877,319,1176,383,449,266,2333,166,1247,253,871,342,378,325,882
|
0.3854834577363446,2.12722970929693,-0.7632007073119792,1.014100175743301,0.09036639678564706,0.8533559354124849,0.7108269558541094,1.2126457954814382,-0.40806438662984673,1.7985369233817154,0.06254274771127205,1.276921824455599,0.2804141068248859,0.9687588066338071,0.8766756507402944,1.014100175743301,0.2804141068248859
| 3,367
|
Monovalent inorganic cation homeostasis
| 11
| 25
| 2.577384
| 0.009955
|
O75503,Q92544,Q96PU5,Q15904,Q9Y5X3,Q8N511,Q9Y487,P06576,P50897,Q93050,Q9UI12
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
102,489,268,173,567,48,215,435,26,92,585
|
102,891,1870,610,435,2180,2763,2431,26,1019,1126,2322,746,1417,173,48,489,92,1318,268,2162,585,215,567,2536
|
2.40057096317167,0.2537554699892711,-0.22570012371921228,0.488136037900703,0.7348993205919421,-0.34644068419145774,-0.6634903102109926,-0.4705554931571856,3.6904275097045454,0.17280963840827135,0.11801732694304702,-0.40806438662984673,0.3594471701790773,-0.02198676428679048,1.722120594018782,3.286174597616811,0.6622900003005412,2.5793442451134623,0.034544176031171075,1.2126457954814382,-0.31594654169938047,0.5385907773537494,1.525203768425511,0.5636060512556167,-0.5021341373910327
| 3,367
|
Abnormal tissue metabolite concentration
| 7
| 15
| 2.572609
| 0.010094
|
Q658P3,P07602,O43933,P06280,P17900,P06865,Q9NZJ7
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
129,65,132,139,169,81,276
|
738,132,319,139,81,65,1064,555,169,1292,449,129,3316,276,733
|
0.3594471701790773,2.12722970929693,1.014100175743301,2.074084118777206,2.781905953857426,3.0911332595741183,0.14549770029311399,0.5636060512556167,1.7413465847323417,0.034544176031171075,0.7108269558541094,2.16231565108635,-1.5322507832020744,1.1692778855749448,0.3854834577363446
| 3,367
|
Protein transmembrane transport
| 12
| 24
| 2.572393
| 0.0101
|
Q9NS69,O43933,O95831,O75381,O60830,Q15629,Q99595,P49755,Q99442,O96008,O14925,P31751
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
3,132,35,319,9,10,11,437,176,466,464,257
|
464,513,132,9,319,2649,35,466,3034,2599,257,437,3286,3222,2194,852,10,826,2737,176,11,2797,3,766
|
0.6866243286062695,0.6132203653820887,2.12722970929693,4.521067264147013,1.014100175743301,-0.5982416058990344,3.512290521765781,0.6866243286062695,-0.8997389788237078,-0.5659738392609449,1.2555985905367433,0.7348993205919421,-1.37506621536203,-1.1493154316371736,-0.34644068419145774,0.2804141068248859,4.2752571823438945,0.30691434248850596,-0.6307459142786708,1.722120594018782,4.253245556056843,-0.6634903102109926,4.832811783410612,0.3594471701790773
| 3,367
|
EF-hand domain [IPR002048]
| 15
| 42
| 2.563103
| 0.010374
|
Q9UPN3,O43707,O43852,O75746,O75071,P12814,Q13813,Q03001,Q02818,P80303,Q9BRK5,Q9Y680,Q9UJS0,Q14257,O95202
|
Sequence
|
InterPro Domain
|
interpro_domain
|
494,410,196,381,68,448,292,423,46,15,148,178,546,151,123
|
410,196,68,2544,381,123,2485,2549,448,2838,972,1346,1181,2491,2887,810,778,2897,15,46,423,292,151,2945,1361,1898,599,2573,2056,534,1367,2408,916,3078,1376,148,649,881,2469,546,494,178
|
0.7826588994764823,1.605007630123358,2.975802844788199,-0.5339391468977894,0.8533559354124849,2.19713106377011,-0.5021341373910327,-0.5339391468977894,0.7108269558541094,-0.7297139540963061,0.1999552233330087,0.0063684354015670136,0.09036639678564706,-0.5021341373910327,-0.7632007073119792,0.30691434248850596,0.3332580754721944,-0.7632007073119792,4.164124775027304,3.286174597616811,0.7588428378146155,1.1034296234289172,1.9840930614703445,-0.7969425638483784,0.0063684354015670136,-0.22570012371921228,0.5134346459158582,-0.5339391468977894,-0.28566029525923553,0.588482059091134,0.0063684354015670136,-0.43919996831517205,0.2537554699892711,-0.9345419567612725,0.0063684354015670136,2.002235460610414,0.46269330605308917,0.2804141068248859,-0.4705554931571856,0.588482059091134,0.6622900003005412,1.722120594018782
| 3,367
|
Vascular process in circulatory system
| 8
| 32
| 2.559721
| 0.010476
|
Q9HB40,P53985,P02786,P42892,P08183,Q16625,P30825,P41440
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
34,103,200,43,110,242,89,186
|
735,2363,1526,1226,3330,594,200,3255,110,692,2599,436,89,186,43,1666,1465,103,2322,818,819,1476,1963,615,2049,906,242,1822,2142,259,34,877
|
0.3594471701790773,-0.43919996831517205,-0.07924492702588042,0.06254274771127205,-1.6129965081754174,0.5134346459158582,1.5851890116525102,-1.2607479309781038,2.2999956417932186,0.41136873678446767,-0.5659738392609449,0.7348993205919421,2.6583280208911844,1.6639450277501382,3.34039786005235,-0.1372495529245524,-0.05052375805598644,2.40057096317167,-0.40806438662984673,0.30691434248850596,0.30691434248850596,-0.05052375805598644,-0.25557908848123395,0.488136037900703,-0.28566029525923553,0.2537554699892711,1.3402905479186136,-0.19602066046695343,-0.31594654169938047,1.2555985905367433,3.525248122809391,0.2804141068248859
| 3,367
|
Lipid binding
| 27
| 145
| 2.553441
| 0.010666
|
Q14108,Q14849,Q9BQE5,P21796,Q9UM22,P45880,Q9NZJ7,O15254,O60313,P50897,Q9H490,Q9Y5X1,P28070,O00429,A6NIH7,Q8WTV0,Q8NCC3,P30536,P07602,P61916,O14773,O15173,O15118,P11717,Q15067,O00264,P04062
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
5,6,8,13,14,19,276,149,279,26,289,30,36,300,57,60,63,191,65,197,70,74,85,217,232,106,118
|
589,2425,57,106,1225,300,735,495,1113,70,392,1391,85,74,149,2018,924,279,3282,465,1227,2023,1281,118,2484,610,2370,65,2309,1655,1656,2653,3034,1940,1658,2550,217,3117,929,13,2314,2929,3172,36,612,1184,3151,191,2814,308,2382,383,19,2494,779,2435,26,976,2662,3248,979,2437,2608,2818,1805,449,197,3178,1547,1472,518,695,1300,2613,1078,820,2042,1242,2446,5,2202,6,988,3224,232,361,1360,2678,577,1201,2053,2737,911,1627,63,868,913,60,1257,1497,2142,835,1700,3346,1096,791,3109,1507,2692,2955,1508,8,2693,1378,1990,491,1327,1213,761,289,1214,582,1330,650,877,2912,276,880,2294,2998,1579,547,1847,14,2870,1159,960,651,511,3299,2966,1932,564,30,567
|
0.5134346459158582,-0.4705554931571856,3.2036080031326675,2.333769977004763,0.06254274771127205,1.081263578277897,0.3594471701790773,0.6378225083090472,0.11801732694304702,2.9465065973455364,0.8299141117114622,-0.02198676428679048,2.7359582136753127,2.9317872528718985,1.9840930614703445,-0.28566029525923553,0.22693649856222178,1.1474357022138544,-1.37506621536203,0.6866243286062695,0.06254274771127205,-0.28566029525923553,0.034544176031171075,2.248856101291637,-0.5021341373910327,0.488136037900703,-0.43919996831517205,3.0911332595741183,-0.40806438662984673,-0.1372495529245524,-0.1372495529245524,-0.5982416058990344,-0.8997389788237078,-0.25557908848123395,-0.1372495529245524,-0.5339391468977894,1.5050295510613063,-1.004980242603473,0.22693649856222178,4.220028343416946,-0.40806438662984673,-0.7969425638483784,-1.0765587039609845,3.473195069920084,0.488136037900703,0.09036639678564706,-1.0406246148817728,1.6247393272059847,-0.6964784202356398,1.058987402257529,-0.43919996831517205,0.8533559354124849,3.9215673900004977,-0.5021341373910327,0.3332580754721944,-0.4705554931571856,3.6904275097045454,0.1999552233330087,-0.5982416058990344,-1.2232904675772427,0.1999552233330087,-0.4705554931571856,-0.5659738392609449,-0.6964784202356398,-0.19602066046695343,0.7108269558541094,1.605007630123358,-1.0765587039609845,-0.07924492702588042,-0.05052375805598644,0.6132203653820887,0.41136873678446767,0.034544176031171075,-0.5659738392609449,0.14549770029311399,0.30691434248850596,-0.28566029525923553,0.06254274771127205,-0.4705554931571856,4.744465578955981,-0.34644068419145774,4.664482621298005,0.1999552233330087,-1.1493154316371736,1.402777585756001,0.8998745416649946,0.0063684354015670136,-0.5982416058990344,0.5385907773537494,0.09036639678564706,-0.28566029525923553,-0.6307459142786708,0.2537554699892711,-0.10815269963874782,3.1336381893089387,0.2804141068248859,0.2537554699892711,3.1896999455248927,0.06254274771127205,-0.05052375805598644,-0.31594654169938047,0.30691434248850596,-0.1372495529245524,-1.7790704476183576,0.14549770029311399,0.3332580754721944,-0.969620885690122,-0.05052375805598644,-0.5982416058990344,-0.7969425638483784,-0.05052375805598644,4.552178889851971,-0.5982416058990344,0.0063684354015670136,-0.25557908848123395,0.6622900003005412,0.034544176031171075,0.09036639678564706,0.3594471701790773,1.1254866370979533,0.09036639678564706,0.5385907773537494,0.034544176031171075,0.46269330605308917,0.2804141068248859,-0.7632007073119792,1.1692778855749448,0.2804141068248859,-0.37714563952921315,-0.8309434988946349,-0.07924492702588042,0.588482059091134,-0.19602066046695343,4.1865682400285555,-0.7297139540963061,0.11801732694304702,0.22693649856222178,0.46269330605308917,0.6378225083090472,-1.45295805178107,-0.7969425638483784,-0.22570012371921228,0.5636060512556167,3.614933961940769,0.5636060512556167
| 3,367
|
membrane trafficking regulatory protein
| 8
| 21
| 2.551708
| 0.01072
|
P24390,Q14108,P11279,Q15075,P13473,O43760,Q15833,Q8WTV0
|
Functions
|
Panther Protein class
|
panther_protein_class
|
2,5,261,361,210,216,501,60
|
1855,887,495,216,926,261,210,2,5,361,3277,501,60,914,1696,1318,674,1921,2639,1155,2293
|
-0.22570012371921228,0.2537554699892711,0.6378225083090472,1.5050295510613063,0.22693649856222178,1.2341735778065615,1.5452878774447738,5.106453588871854,4.744465578955981,0.8998745416649946,-1.3366301135330916,0.6378225083090472,3.1896999455248927,0.2537554699892711,-0.1372495529245524,0.034544176031171075,0.4371047742428398,-0.22570012371921228,-0.5659738392609449,0.11801732694304702,-0.37714563952921315
| 3,367
|
Glycosyltransferase
| 9
| 31
| 2.549008
| 0.010803
|
O43505,Q8TCJ2,Q10472,P43490,P04062,Q2TAA5,P46977,Q86SF2,Q13126
|
Functions
|
Protein Atlas Molecular function
|
protein_atlas_molecular_function
|
195,341,208,335,118,248,188,317,95
|
2018,195,1526,1654,2103,2927,118,1117,2652,2374,2654,1873,1179,1662,335,188,1416,1357,664,208,95,248,1624,317,2346,341,378,630,1918,1440,1006
|
-0.28566029525923553,1.605007630123358,-0.07924492702588042,-0.1372495529245524,-0.31594654169938047,-0.7969425638483784,2.248856101291637,0.11801732694304702,-0.5982416058990344,-0.43919996831517205,-0.5982416058990344,-0.22570012371921228,0.09036639678564706,-0.1372495529245524,0.9687588066338071,1.6443848730963768,-0.02198676428679048,0.0063684354015670136,0.4371047742428398,1.5652826911718993,2.4663995632740083,1.2981442560194676,-0.10815269963874782,1.0365999791862452,-0.40806438662984673,0.9687588066338071,0.8766756507402944,0.488136037900703,-0.22570012371921228,-0.02198676428679048,0.1999552233330087
| 3,367
|
N glycan biosynthesis
| 6
| 15
| 2.545935
| 0.010899
|
P04843,Q16706,O60476,Q86YN1,Q2TAA5,P46977
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
254,294,235,174,248,188
|
235,1654,2544,254,1173,1601,188,2196,2126,1746,294,248,174,341,630
|
1.3820450016487578,-0.1372495529245524,-0.5339391468977894,1.2555985905367433,0.09036639678564706,-0.10815269963874782,1.6443848730963768,-0.34644068419145774,-0.31594654169938047,-0.16653801380920247,1.1034296234289172,1.2981442560194676,1.722120594018782,0.9687588066338071,0.488136037900703
| 3,367
|
Delusions
| 10
| 22
| 2.545614
| 0.010909
|
P42858,P07602,Q96RL7,Q9BQE5,P21964,O00754,Q9NZJ7,Q9UJS0,Q96DF8,P04062
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
344,65,297,8,396,480,276,546,309,118
|
480,738,118,65,2372,555,396,3071,2187,344,1461,1733,1419,1681,2455,309,297,8,1443,276,2531,546
|
0.6622900003005412,0.3594471701790773,2.248856101291637,3.0911332595741183,-0.43919996831517205,0.5636060512556167,0.8299141117114622,-0.9345419567612725,-0.34644068419145774,0.9459148854023514,-0.05052375805598644,-0.16653801380920247,-0.02198676428679048,-0.1372495529245524,-0.4705554931571856,1.058987402257529,1.1034296234289172,4.552178889851971,-0.02198676428679048,1.1692778855749448,-0.5021341373910327,0.588482059091134
| 3,367
|
Chemical homeostasis
| 41
| 164
| 2.54361
| 0.010971
|
P09601,P30519,Q658P3,Q99808,Q5BJF2,Q6P4Q7,Q96PU5,P51572,Q96A33,P42785,O15254,P50897,Q15043,P16615,Q15904,Q8N511,Q9Y6C9,P35610,Q8WTV0,P30536,P61916,P02786,Q96TC7,P34913,O15118,Q9Y487,P05067,Q8NE01,Q93050,Q9NQC3,Q12846,P42858,O75503,P53985,Q15067,Q16891,Q9HD20,P04062,O15260,O95202,Q9P035
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
0,1,129,259,7,400,268,273,274,21,149,26,293,290,173,48,306,308,60,191,197,200,343,207,85,215,90,351,92,96,345,344,102,103,232,363,115,118,121,123,260
|
1855,2171,1717,1452,2363,85,149,121,654,2303,593,1015,102,568,3253,393,2548,123,926,891,1170,1456,2101,200,118,3255,1870,610,90,435,1117,1795,1064,1655,1723,1656,0,2374,2180,2881,1942,1118,2928,290,694,2026,808,1181,2655,436,774,2314,2763,3070,2764,612,2317,2431,2603,1,191,2491,207,308,2976,777,2032,21,344,1666,1465,26,1019,1238,273,1605,103,1126,2322,3153,746,197,1808,2261,3158,816,2938,934,1959,1417,3276,2499,2776,345,1815,3352,519,3290,2042,1891,1554,1359,293,232,618,2049,3277,173,2570,2677,363,7,129,598,400,1029,2512,1758,534,2211,1692,48,351,1493,868,1367,60,1090,489,92,274,1318,2143,2739,268,1094,837,343,3280,259,1376,1378,1839,762,1512,2741,1442,115,96,2079,2225,260,711,2162,585,1579,2229,1581,2703,215,734,567,2536,306
|
-0.22570012371921228,-0.34644068419145774,-0.16653801380920247,-0.05052375805598644,-0.43919996831517205,2.7359582136753127,1.9840930614703445,2.214438638015626,0.4371047742428398,-0.40806438662984673,0.5134346459158582,0.17280963840827135,2.40057096317167,0.5385907773537494,-1.2607479309781038,0.8299141117114622,-0.5339391468977894,2.19713106377011,0.22693649856222178,0.2537554699892711,0.09036639678564706,-0.05052375805598644,-0.31594654169938047,1.5851890116525102,2.248856101291637,-1.2607479309781038,-0.22570012371921228,0.488136037900703,2.595251590463738,0.7348993205919421,0.11801732694304702,-0.19602066046695343,0.14549770029311399,-0.1372495529245524,-0.16653801380920247,-0.1372495529245524,5.77073025593568,-0.43919996831517205,-0.34644068419145774,-0.7632007073119792,-0.25557908848123395,0.11801732694304702,-0.7969425638483784,1.1034296234289172,0.41136873678446767,-0.28566029525923553,0.30691434248850596,0.09036639678564706,-0.5982416058990344,0.7348993205919421,0.3332580754721944,-0.40806438662984673,-0.6634903102109926,-0.9345419567612725,-0.6634903102109926,0.488136037900703,-0.40806438662984673,-0.4705554931571856,-0.5659738392609449,5.215090048676801,1.6247393272059847,-0.5021341373910327,1.5652826911718993,1.058987402257529,-0.8309434988946349,0.3332580754721944,-0.28566029525923553,3.8498324746709085,0.9459148854023514,-0.1372495529245524,-0.05052375805598644,3.6904275097045454,0.17280963840827135,0.06254274771127205,1.1692778855749448,-0.10815269963874782,2.40057096317167,0.11801732694304702,-0.40806438662984673,-1.0406246148817728,0.3594471701790773,1.605007630123358,-0.19602066046695343,-0.37714563952921315,-1.0406246148817728,0.30691434248850596,-0.7969425638483784,0.22693649856222178,-0.25557908848123395,-0.02198676428679048,-1.3366301135330916,-0.5021341373910327,-0.6634903102109926,0.9459148854023514,-0.19602066046695343,-1.907862431915821,0.6132203653820887,-1.4138401674883982,-0.28566029525923553,-0.22570012371921228,-0.07924492702588042,0.0063684354015670136,1.1034296234289172,1.402777585756001,0.488136037900703,-0.28566029525923553,-1.3366301135330916,1.722120594018782,-0.5339391468977894,-0.5982416058990344,0.8998745416649946,4.552178889851971,2.16231565108635,0.5134346459158582,0.8299141117114622,0.17280963840827135,-0.5021341373910327,-0.16653801380920247,0.588482059091134,-0.34644068419145774,-0.1372495529245524,3.286174597616811,0.9459148854023514,-0.05052375805598644,0.2804141068248859,0.0063684354015670136,3.1896999455248927,0.14549770029311399,0.6622900003005412,2.5793442451134623,1.1692778855749448,0.034544176031171075,-0.31594654169938047,-0.6307459142786708,1.2126457954814382,0.14549770029311399,0.30691434248850596,0.9687588066338071,-1.3366301135330916,1.2555985905367433,0.0063684354015670136,0.0063684354015670136,-0.19602066046695343,0.3594471701790773,-0.05052375805598644,-0.6307459142786708,-0.02198676428679048,2.283013353361886,2.433605013064534,-0.28566029525923553,-0.34644068419145774,1.2555985905367433,0.41136873678446767,-0.31594654169938047,0.5385907773537494,-0.07924492702588042,-0.34644068419145774,-0.07924492702588042,-0.5982416058990344,1.525203768425511,0.3854834577363446,0.5636060512556167,-0.5021341373910327,1.081263578277897
| 3,367
|
Abnormality of the tongue
| 30
| 100
| 2.541861
| 0.011026
|
O43933,Q01082,P83436,Q10713,Q96A33,Q7LGA3,P48651,Q71SY5,O95831,Q8NCM8,P10253,Q96RL7,P16278,P01889,P04066,Q9UBM7,O75381,P42356,Q03252,P56589,Q9Y4P3,Q13510,P98175,Q6NUK1,O60826,O75431,P20700,O00754,Q2M1P5,O75844
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
132,518,517,398,274,152,533,33,35,537,163,297,41,302,184,325,319,571,328,449,205,78,451,599,593,97,359,480,253,127
|
1854,735,2707,480,962,1114,2751,3065,2540,132,593,1789,319,97,1395,127,2023,1794,35,302,805,184,1283,1064,2105,163,2599,41,359,1537,3012,2430,2656,2431,1661,1799,571,1349,3124,533,743,660,1238,2818,449,781,1739,1412,517,451,518,1960,328,1417,2396,398,2611,2776,1194,78,903,1817,1426,1307,2946,253,2136,1137,599,33,152,537,1910,672,274,1318,297,628,1506,1097,952,2220,954,955,2741,1993,956,2464,1515,2000,879,3083,325,2227,958,205,2090,2967,712,1274
|
-0.22570012371921228,0.3594471701790773,-0.6307459142786708,0.6622900003005412,0.1999552233330087,0.11801732694304702,-0.6634903102109926,-0.9345419567612725,-0.5339391468977894,2.12722970929693,0.5134346459158582,-0.19602066046695343,1.014100175743301,2.4171181472402936,-0.02198676428679048,2.16231565108635,-0.28566029525923553,-0.19602066046695343,3.512290521765781,1.081263578277897,0.30691434248850596,1.6639450277501382,0.034544176031171075,0.14549770029311399,-0.31594654169938047,1.8362643641609107,-0.5659738392609449,3.367269068562799,0.8998745416649946,-0.07924492702588042,-0.8652075817496219,-0.4705554931571856,-0.5982416058990344,-0.4705554931571856,-0.1372495529245524,-0.19602066046695343,0.5385907773537494,0.0063684354015670136,-1.004980242603473,0.588482059091134,0.3594471701790773,0.4371047742428398,0.06254274771127205,-0.6964784202356398,0.7108269558541094,0.3332580754721944,-0.16653801380920247,-0.02198676428679048,0.6132203653820887,0.7108269558541094,0.6132203653820887,-0.25557908848123395,0.9914868411153721,-0.02198676428679048,-0.43919996831517205,0.8299141117114622,-0.5659738392609449,-0.6634903102109926,0.09036639678564706,2.8724277004854066,0.2537554699892711,-0.19602066046695343,-0.02198676428679048,0.034544176031171075,-0.7969425638483784,1.276921824455599,-0.31594654169938047,0.11801732694304702,0.5134346459158582,3.525248122809391,1.9840930614703445,0.588482059091134,-0.22570012371921228,0.4371047742428398,1.1692778855749448,0.034544176031171075,1.1034296234289172,0.488136037900703,-0.05052375805598644,0.14549770029311399,0.22693649856222178,-0.34644068419145774,0.22693649856222178,0.22693649856222178,-0.6307459142786708,-0.25557908848123395,0.22693649856222178,-0.4705554931571856,-0.05052375805598644,-0.25557908848123395,0.2804141068248859,-0.9345419567612725,1.014100175743301,-0.34644068419145774,0.22693649856222178,1.5851890116525102,-0.28566029525923553,-0.7969425638483784,0.41136873678446767,0.06254274771127205
| 3,367
|
Calcium ion binding
| 27
| 83
| 2.538529
| 0.011132
|
O75746,Q9UM22,P80303,Q9BRK5,Q96A33,Q9UJS0,Q14257,Q8IYU8,P19022,O43707,Q9Y4G8,Q13813,P16615,Q03001,Q02818,P27824,P15289,Q9Y680,Q8WVQ1,O75071,O43852,P12814,Q6NUK1,O94813,Q9UPN3,O60476,O95202
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
381,14,15,148,274,546,151,534,286,410,564,292,290,423,46,556,555,178,457,68,196,448,599,594,494,235,123
|
589,800,738,410,196,235,68,2544,2098,381,594,123,2484,1283,2485,2370,2549,1655,2653,448,1942,2838,972,1118,555,1875,290,1346,286,1181,929,2601,2764,556,3150,2491,2887,810,778,779,976,2897,850,1296,15,46,423,1476,2499,1744,292,858,1478,151,2945,1361,1898,599,3101,2737,2573,2056,534,1367,2408,457,274,916,3078,1373,2692,1376,148,2693,649,881,2469,2162,546,14,494,564,178
|
0.5134346459158582,0.30691434248850596,0.3594471701790773,0.7826588994764823,1.605007630123358,1.3820450016487578,2.975802844788199,-0.5339391468977894,-0.31594654169938047,0.8533559354124849,0.5134346459158582,2.19713106377011,-0.5021341373910327,0.034544176031171075,-0.5021341373910327,-0.43919996831517205,-0.5339391468977894,-0.1372495529245524,-0.5982416058990344,0.7108269558541094,-0.25557908848123395,-0.7297139540963061,0.1999552233330087,0.11801732694304702,0.5636060512556167,-0.22570012371921228,1.1034296234289172,0.0063684354015670136,1.1254866370979533,0.09036639678564706,0.22693649856222178,-0.5659738392609449,-0.6634903102109926,0.5636060512556167,-1.0406246148817728,-0.5021341373910327,-0.7632007073119792,0.30691434248850596,0.3332580754721944,0.3332580754721944,0.1999552233330087,-0.7632007073119792,0.2804141068248859,0.034544176031171075,4.164124775027304,3.286174597616811,0.7588428378146155,-0.05052375805598644,-0.5021341373910327,-0.16653801380920247,1.1034296234289172,0.2804141068248859,-0.05052375805598644,1.9840930614703445,-0.7969425638483784,0.0063684354015670136,-0.22570012371921228,0.5134346459158582,-0.969620885690122,-0.6307459142786708,-0.5339391468977894,-0.28566029525923553,0.588482059091134,0.0063684354015670136,-0.43919996831517205,0.7108269558541094,1.1692778855749448,0.2537554699892711,-0.9345419567612725,0.0063684354015670136,-0.5982416058990344,0.0063684354015670136,2.002235460610414,-0.5982416058990344,0.46269330605308917,0.2804141068248859,-0.4705554931571856,-0.31594654169938047,0.588482059091134,4.1865682400285555,0.6622900003005412,0.5636060512556167,1.722120594018782
| 3,367
|
Mitochondrial calcium ion transport
| 7
| 16
| 2.537785
| 0.011156
|
Q8IYU8,Q10713,P21796,P45880,Q9Y277,O95202,Q96TA2
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
534,398,13,19,548,123,648
|
2595,123,13,2031,19,398,534,1493,1090,1436,648,1507,1376,1579,548,734
|
-0.5659738392609449,2.19713106377011,4.220028343416946,-0.28566029525923553,3.9215673900004977,0.8299141117114622,0.588482059091134,-0.05052375805598644,0.14549770029311399,-0.02198676428679048,0.46269330605308917,-0.05052375805598644,0.0063684354015670136,-0.07924492702588042,0.588482059091134,0.3854834577363446
| 3,367
|
Osteopenia
| 15
| 69
| 2.536215
| 0.011206
|
O75431,P07602,Q14108,Q32P28,Q9Y4P3,O75844,Q9NZC9,O75718,Q9NZJ7,Q9NSD9,Q9Y487,P04062,Q96L58,Q9H490,Q13126
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
97,65,5,140,205,127,444,206,276,474,215,118,378,289,95
|
2425,1854,2093,480,2363,1276,771,2711,2540,1526,97,1863,206,127,805,118,3087,1117,1345,65,1176,2838,1286,975,2248,2718,1661,1601,777,2032,2321,1292,1470,1953,614,2194,781,3018,1412,3098,854,1192,696,95,5,1426,1556,140,1311,1428,1620,1824,1763,1983,1092,916,871,378,1571,289,474,1154,444,276,958,2233,215,205,3187
|
-0.4705554931571856,-0.22570012371921228,-0.31594654169938047,0.6622900003005412,-0.43919996831517205,0.034544176031171075,0.3332580754721944,-0.6307459142786708,-0.5339391468977894,-0.07924492702588042,2.4171181472402936,-0.22570012371921228,1.5652826911718993,2.16231565108635,0.30691434248850596,2.248856101291637,-0.969620885690122,0.11801732694304702,0.0063684354015670136,3.0911332595741183,0.09036639678564706,-0.7297139540963061,0.034544176031171075,0.1999552233330087,-0.37714563952921315,-0.6307459142786708,-0.1372495529245524,-0.10815269963874782,0.3332580754721944,-0.28566029525923553,-0.40806438662984673,0.034544176031171075,-0.05052375805598644,-0.25557908848123395,0.488136037900703,-0.34644068419145774,0.3332580754721944,-0.8652075817496219,-0.02198676428679048,-0.969620885690122,0.2804141068248859,0.09036639678564706,0.41136873678446767,2.4663995632740083,4.744465578955981,-0.02198676428679048,-0.07924492702588042,2.0383028111640002,0.034544176031171075,-0.02198676428679048,-0.10815269963874782,-0.19602066046695343,-0.16653801380920247,-0.25557908848123395,0.14549770029311399,0.2537554699892711,0.2804141068248859,0.8766756507402944,-0.07924492702588042,1.1254866370979533,0.6866243286062695,0.11801732694304702,0.7348993205919421,1.1692778855749448,0.22693649856222178,-0.34644068419145774,1.525203768425511,1.5851890116525102,-1.0765587039609845
| 3,367
|
Iron ion homeostasis
| 7
| 18
| 2.534874
| 0.011249
|
P09601,Q658P3,P30519,P02786,Q15904,Q8N511,Q9Y487
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
0,129,1,200,173,48,215
|
1015,3253,200,3255,0,774,1,2491,2976,746,3290,2042,293,173,129,48,1512,215
|
0.17280963840827135,-1.2607479309781038,1.5851890116525102,-1.2607479309781038,5.77073025593568,0.3332580754721944,5.215090048676801,-0.5021341373910327,-0.8309434988946349,0.3594471701790773,-1.4138401674883982,-0.28566029525923553,1.1034296234289172,1.722120594018782,2.16231565108635,3.286174597616811,-0.05052375805598644,1.525203768425511
| 3,367
|
Exopeptidase activity
| 10
| 31
| 2.532315
| 0.011331
|
P10619,Q9HB40,O14773,Q9NZ08,Q9UIQ6,P55786,P42785,O75976,Q9H3G5,O75844
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
190,34,70,168,105,84,21,183,27,127
|
70,127,183,200,655,190,3214,2765,2603,2187,21,3315,1125,84,3351,452,3130,2825,322,1566,3106,1437,2692,27,2150,34,2864,3111,2080,168,105
|
2.9465065973455364,2.16231565108635,1.6639450277501382,1.5851890116525102,0.4371047742428398,1.6247393272059847,-1.1493154316371736,-0.6634903102109926,-0.5659738392609449,-0.34644068419145774,3.8498324746709085,-1.5322507832020744,0.11801732694304702,2.7513259355917703,-1.907862431915821,0.7108269558541094,-1.004980242603473,-0.6964784202356398,1.014100175743301,-0.07924492702588042,-0.969620885690122,-0.02198676428679048,-0.5982416058990344,3.6904275097045454,-0.31594654169938047,3.525248122809391,-0.7297139540963061,-0.969620885690122,-0.28566029525923553,1.7795540517583925,2.36729383704207
| 3,367
|
Basolateral plasma membrane
| 13
| 38
| 2.517771
| 0.01181
|
Q12846,Q99808,O75955,P35613,P53985,Q15043,Q6P4Q7,P02786,Q14254,O14936,P30825,P41440,P19022
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
345,259,162,165,103,293,400,200,338,277,89,186,286
|
1855,277,162,1229,200,2484,610,2370,807,1065,692,1658,2109,973,3355,286,436,611,89,742,165,186,103,1126,2322,1735,819,1476,345,1815,858,1965,338,293,400,1037,2690,259
|
-0.22570012371921228,1.1474357022138544,1.8550102756937976,0.06254274771127205,1.5851890116525102,-0.5021341373910327,0.488136037900703,-0.43919996831517205,0.30691434248850596,0.14549770029311399,0.41136873678446767,-0.1372495529245524,-0.31594654169938047,0.1999552233330087,-1.9957969029261853,1.1254866370979533,0.7348993205919421,0.488136037900703,2.6583280208911844,0.3594471701790773,1.7985369233817154,1.6639450277501382,2.40057096317167,0.11801732694304702,-0.40806438662984673,-0.16653801380920247,0.30691434248850596,-0.05052375805598644,0.9459148854023514,-0.19602066046695343,0.2804141068248859,-0.25557908848123395,0.9687588066338071,1.1034296234289172,0.8299141117114622,0.17280963840827135,-0.5982416058990344,1.2555985905367433
| 3,367
|
Protease
| 14
| 87
| 2.515187
| 0.011897
|
P10619,Q9HB40,O14773,Q9UIQ6,Q9NZ08,P42892,P28072,P55786,P42785,O75976,P28074,Q9H3G5,P67812,O75844
|
Functions
|
Protein Atlas Molecular function
|
protein_atlas_molecular_function
|
190,34,70,105,168,43,170,84,21,183,119,27,93,127
|
2092,2094,70,550,2595,127,183,967,804,2549,655,190,3214,2109,1346,170,119,2765,2603,849,2434,2891,21,43,2721,3221,3315,2607,1188,1070,1125,2935,84,899,93,1958,2441,2198,452,2849,1025,2335,439,347,375,1689,2135,1136,1031,3104,3130,1625,2408,202,1497,724,1983,1984,3297,365,458,1437,1322,648,1772,3280,507,708,27,2150,681,1042,34,2864,3111,493,2080,168,1642,1334,105,607,732,1339,2089,734,2917
|
-0.31594654169938047,-0.31594654169938047,2.9465065973455364,0.5636060512556167,-0.5659738392609449,2.16231565108635,1.6639450277501382,0.1999552233330087,0.30691434248850596,-0.5339391468977894,0.4371047742428398,1.6247393272059847,-1.1493154316371736,-0.31594654169938047,0.0063684354015670136,1.7413465847323417,2.2316801472635333,-0.6634903102109926,-0.5659738392609449,0.2804141068248859,-0.4705554931571856,-0.7632007073119792,3.8498324746709085,3.34039786005235,-0.6307459142786708,-1.1493154316371736,-1.5322507832020744,-0.5659738392609449,0.09036639678564706,0.14549770029311399,0.11801732694304702,-0.7969425638483784,2.7513259355917703,0.2537554699892711,2.5151499572076714,-0.25557908848123395,-0.4705554931571856,-0.34644068419145774,0.7108269558541094,-0.7297139540963061,0.17280963840827135,-0.40806438662984673,0.7348993205919421,0.9459148854023514,0.8766756507402944,-0.1372495529245524,-0.31594654169938047,0.11801732694304702,0.17280963840827135,-0.969620885690122,-1.004980242603473,-0.10815269963874782,-0.43919996831517205,1.5851890116525102,-0.05052375805598644,0.3854834577363446,-0.25557908848123395,-0.25557908848123395,-1.45295805178107,0.8998745416649946,0.7108269558541094,-0.02198676428679048,0.034544176031171075,0.46269330605308917,-0.16653801380920247,-1.3366301135330916,0.6378225083090472,0.41136873678446767,3.6904275097045454,-0.31594654169938047,0.4371047742428398,0.17280963840827135,3.525248122809391,-0.7297139540963061,-0.969620885690122,0.6622900003005412,-0.28566029525923553,1.7795540517583925,-0.10815269963874782,0.034544176031171075,2.36729383704207,0.5134346459158582,0.3854834577363446,0.034544176031171075,-0.28566029525923553,0.3854834577363446,-0.7632007073119792
| 3,367
|
Cellular monovalent inorganic cation homeostasis
| 10
| 23
| 2.513098
| 0.011968
|
O75503,Q92544,Q96PU5,Q15904,Q8N511,Q9Y487,P06576,P50897,Q93050,Q9UI12
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
102,489,268,173,48,215,435,26,92,585
|
102,891,610,435,2180,2763,2431,26,1019,1126,2322,746,1417,173,48,489,92,1318,268,2162,585,215,2536
|
2.40057096317167,0.2537554699892711,0.488136037900703,0.7348993205919421,-0.34644068419145774,-0.6634903102109926,-0.4705554931571856,3.6904275097045454,0.17280963840827135,0.11801732694304702,-0.40806438662984673,0.3594471701790773,-0.02198676428679048,1.722120594018782,3.286174597616811,0.6622900003005412,2.5793442451134623,0.034544176031171075,1.2126457954814382,-0.31594654169938047,0.5385907773537494,1.525203768425511,-0.5021341373910327
| 3,367
|
Apical plasma membrane
| 17
| 39
| 2.510555
| 0.012054
|
P30825,Q99808,O75955,P35241,Q9Y4G8,P53985,Q15043,Q14254,P08183,Q13131,P05023,P26038,Q16625,P20020,Q86UE4,P41440,P19022
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
89,259,162,657,564,103,293,338,110,519,610,611,242,436,153,186,286
|
1855,2363,1391,162,2480,2484,610,110,807,1723,1065,692,3011,973,286,436,1537,611,89,657,1539,2187,2976,186,103,1126,2322,746,519,2943,338,293,1309,242,153,259,1218,1268,564
|
-0.22570012371921228,-0.43919996831517205,-0.02198676428679048,1.8550102756937976,-0.5021341373910327,-0.5021341373910327,0.488136037900703,2.2999956417932186,0.30691434248850596,-0.16653801380920247,0.14549770029311399,0.41136873678446767,-0.8652075817496219,0.1999552233330087,1.1254866370979533,0.7348993205919421,-0.07924492702588042,0.488136037900703,2.6583280208911844,0.4371047742428398,-0.07924492702588042,-0.34644068419145774,-0.8309434988946349,1.6639450277501382,2.40057096317167,0.11801732694304702,-0.40806438662984673,0.3594471701790773,0.6132203653820887,-0.7969425638483784,0.9687588066338071,1.1034296234289172,0.034544176031171075,1.3402905479186136,1.9840930614703445,1.2555985905367433,0.09036639678564706,0.06254274771127205,0.5636060512556167
| 3,367
|
Amide binding
| 17
| 104
| 2.507936
| 0.012144
|
P24390,P07602,Q9H7Z7,O14773,Q9UIQ6,Q9NZ08,P42892,Q15392,P21796,Q9UM22,O00264,Q99735,Q9Y680,P45880,P55786,P55899,Q8WTV0
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
2,65,67,70,105,168,43,76,13,14,106,147,178,19,84,180,60
|
2537,1340,106,370,888,3318,70,1588,3271,1279,1936,3314,2649,2971,302,333,806,3341,65,1065,554,1594,481,3335,2109,3302,13,2929,3036,2,2029,2764,612,3091,1598,639,308,716,2931,2116,186,43,3246,19,1883,743,1466,2190,812,2978,1020,2557,1070,84,180,2194,852,2195,3158,1956,1547,1741,2264,1355,3099,1476,2499,2670,3200,1081,2199,2042,2046,1424,76,2343,469,60,2411,405,916,2065,835,3350,1263,1507,147,2415,708,762,917,67,763,631,168,276,1106,2228,105,14,2964,2012,2967,178
|
-0.5339391468977894,0.0063684354015670136,2.333769977004763,0.8766756507402944,0.2537554699892711,-1.5724386516725661,2.9465065973455364,-0.10815269963874782,-1.3366301135330916,0.034544176031171075,-0.25557908848123395,-1.5322507832020744,-0.5982416058990344,-0.8309434988946349,1.081263578277897,0.9687588066338071,0.30691434248850596,-1.736960805865547,3.0911332595741183,0.14549770029311399,0.5636060512556167,-0.10815269963874782,0.6622900003005412,-1.6539313317624937,-0.31594654169938047,-1.4924261166507573,4.220028343416946,-0.7969425638483784,-0.8997389788237078,5.106453588871854,-0.28566029525923553,-0.6634903102109926,0.488136037900703,-0.969620885690122,-0.10815269963874782,0.46269330605308917,1.058987402257529,0.3854834577363446,-0.7969425638483784,-0.31594654169938047,1.6639450277501382,3.34039786005235,-1.2232904675772427,3.9215673900004977,-0.22570012371921228,0.3594471701790773,-0.05052375805598644,-0.34644068419145774,0.30691434248850596,-0.8309434988946349,0.17280963840827135,-0.5339391468977894,0.14549770029311399,2.7513259355917703,1.7028121530513547,-0.34644068419145774,0.2804141068248859,-0.34644068419145774,-1.0406246148817728,-0.25557908848123395,-0.07924492702588042,-0.16653801380920247,-0.37714563952921315,0.0063684354015670136,-0.969620885690122,-0.05052375805598644,-0.5021341373910327,-0.5982416058990344,-1.112787329154505,0.14549770029311399,-0.34644068419145774,-0.28566029525923553,-0.28566029525923553,-0.02198676428679048,2.8873405559171093,-0.40806438662984673,0.6866243286062695,3.1896999455248927,-0.43919996831517205,0.8063488749900722,0.2537554699892711,-0.28566029525923553,0.30691434248850596,-1.8645172986247718,0.06254274771127205,-0.05052375805598644,2.002235460610414,-0.43919996831517205,0.41136873678446767,0.3594471701790773,0.2537554699892711,3.062574077848557,0.3594471701790773,0.488136037900703,1.7795540517583925,1.1692778855749448,0.14549770029311399,-0.34644068419145774,2.36729383704207,4.1865682400285555,-0.7969425638483784,-0.25557908848123395,-0.7969425638483784,1.722120594018782
| 3,367
|
Behavior
| 24
| 76
| 2.505383
| 0.012232
|
O76024,Q8N2K0,P50897,P10253,Q96RL7,P17900,P30536,P54802,O15118,Q14203,P80404,P05067,Q13641,P42858,Q92542,P53985,P50416,O00264,Q15154,Q99538,P04062,Q7Z406,P42345,O75844
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
393,419,26,163,297,169,191,83,85,468,211,90,346,344,227,103,485,106,362,507,118,503,498,127
|
2299,106,1391,85,2173,3006,127,1168,393,2548,2927,118,3283,3255,928,90,1531,2714,1795,1064,2652,2245,163,1346,169,2811,2249,2431,191,2252,3177,777,498,2434,344,1879,1949,485,26,2037,103,83,2391,2263,211,1191,1417,519,1241,2042,346,468,362,3277,1753,2735,503,1489,419,1694,227,2458,2526,1209,297,1833,3280,507,762,2291,1995,730,2352,2355,2084,2091
|
-0.40806438662984673,2.333769977004763,-0.02198676428679048,2.7359582136753127,-0.34644068419145774,-0.8652075817496219,2.16231565108635,0.09036639678564706,0.8299141117114622,-0.5339391468977894,-0.7969425638483784,2.248856101291637,-1.37506621536203,-1.2607479309781038,0.22693649856222178,2.595251590463738,-0.07924492702588042,-0.6307459142786708,-0.19602066046695343,0.14549770029311399,-0.5982416058990344,-0.37714563952921315,1.8362643641609107,0.0063684354015670136,1.7413465847323417,-0.6964784202356398,-0.37714563952921315,-0.4705554931571856,1.6247393272059847,-0.37714563952921315,-1.0765587039609845,0.3332580754721944,0.6378225083090472,-0.4705554931571856,0.9459148854023514,-0.22570012371921228,-0.25557908848123395,0.6622900003005412,3.6904275097045454,-0.28566029525923553,2.40057096317167,2.7513259355917703,-0.43919996831517205,-0.37714563952921315,1.525203768425511,0.09036639678564706,-0.02198676428679048,0.6132203653820887,0.06254274771127205,-0.28566029525923553,0.9459148854023514,0.6866243286062695,0.8998745416649946,-1.3366301135330916,-0.16653801380920247,-0.6307459142786708,0.6378225083090472,-0.05052375805598644,0.7826588994764823,-0.1372495529245524,1.443957948969997,-0.4705554931571856,-0.5021341373910327,0.09036639678564706,1.1034296234289172,-0.19602066046695343,-1.3366301135330916,0.6378225083090472,0.3594471701790773,-0.37714563952921315,-0.25557908848123395,0.3854834577363446,-0.40806438662984673,-0.40806438662984673,-0.28566029525923553,-0.28566029525923553
| 3,367
|
Ichthyosis
| 11
| 36
| 2.503323
| 0.012303
|
P48449,O43933,Q15800,O75381,Q15125,Q14691,P04062,O95721,P51648,O95470,P50402
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
98,132,69,319,166,111,118,247,88,250,193
|
2711,132,319,250,247,805,118,3355,1286,975,2248,2889,98,193,88,449,2194,3223,1743,1554,111,166,1247,69,1311,1822,1824,2785,1763,331,581,1571,1921,2585,2233,3187
|
-0.6307459142786708,2.12722970929693,1.014100175743301,1.276921824455599,1.2981442560194676,0.30691434248850596,2.248856101291637,-1.9957969029261853,0.034544176031171075,0.1999552233330087,-0.37714563952921315,-0.7632007073119792,2.4171181472402936,1.6247393272059847,2.6739608306410108,0.7108269558541094,-0.34644068419145774,-1.1493154316371736,-0.16653801380920247,-0.07924492702588042,2.2999956417932186,1.7985369233817154,0.06254274771127205,2.9611783576004687,0.034544176031171075,-0.19602066046695343,-0.19602066046695343,-0.6634903102109926,-0.16653801380920247,0.9914868411153721,0.5385907773537494,-0.07924492702588042,-0.22570012371921228,-0.5339391468977894,-0.34644068419145774,-1.0765587039609845
| 3,367
|
Protease
| 21
| 87
| 3.591001
| 0.000329
|
Q4J6C6,Q9NUQ7,P42785,Q9UPU5,Q9UIQ6,Q9BYT8,Q9HB40,P55786,P28074,Q9NZ08,P48147,Q2T9J0,P28072,P10619,Q16740,P42892,O75844,Q8TCT9,Q96K76,P67812,P83111
|
Functions
|
Protein Atlas Molecular function
|
protein_atlas_molecular_function
|
245,130,3,16,19,154,28,159,35,47,170,49,52,61,62,63,87,235,254,241,243
|
1731,2437,319,1202,1206,87,644,383,888,1476,2917,61,1224,728,818,52,35,2778,2328,733,2335,737,3,63,2599,170,3226,740,594,1365,328,1782,159,596,241,2927,243,3332,2619,2228,1387,62,49,245,402,1664,1154,1535,287,2511,2812,1405,679,235,1548,687,952,2252,851,2993,254,959,1690,961,2824,2951,1177,154,785,2411,786,1299,28,1186,2414,130,701,47,3145,3312,19,457,16,3250,514,3012,2755
|
-0.09094104587744528,-0.3380597911426015,0.6987063152944422,0.10157608769830284,0.10157608769830284,1.7052535001830216,0.38234507015049096,0.6094870655900769,0.24312104666747653,0.005872513874080369,-0.5928502525010018,2.283114015588119,0.10157608769830284,0.3361888423900969,0.2897820267826493,2.431534530000306,3.0039248680970876,-0.4899972174116964,-0.28803660939734893,0.3361888423900969,-0.28803660939734893,0.3361888423900969,7.767211111294991,2.132393733047149,-0.388392317630512,1.1317712009042973,-1.1255266262233685,0.3361888423900969,0.4282542060735226,0.053860976884978005,0.6987063152944422,-0.09094104587744528,1.2159277397438069,0.4282542060735226,0.8744716799879915,-0.5928502525010018,0.8744716799879915,-2.0992610771115365,-0.388392317630512,-0.23831786606746352,0.053860976884978005,2.245653162379946,2.5413946027810876,0.8744716799879915,0.6094870655900769,-0.04239342030431858,0.14902186735214557,0.005872513874080369,0.7870267798407822,-0.3380597911426015,-0.4899972174116964,0.053860976884978005,0.38234507015049096,0.9178727874245445,0.005872513874080369,0.38234507015049096,0.24312104666747653,-0.23831786606746352,0.2897820267826493,-0.6447419635510961,0.8744716799879915,0.24312104666747653,-0.04239342030431858,0.24312104666747653,-0.4899972174116964,-0.5928502525010018,0.14902186735214557,1.257715066848026,0.3361888423900969,-0.28803660939734893,0.3361888423900969,0.10157608769830284,3.4129471399409548,0.14902186735214557,-0.28803660939734893,1.381940746478781,0.38234507015049096,2.5777445433602932,-0.8553842121388305,-1.6881333429715428,4.4014392320994515,0.5645328647779381,5.023653846020728,-1.1804567452748522,0.5193447980380466,-0.6447419635510961,-0.43903817143719953
| 3,367
|
Endopeptidase activity
| 22
| 64
| 3.300723
| 0.000964
|
P60900,Q4J6C6,P49721,Q9UPU5,Q70CQ2,Q9BYT8,P28074,P48147,Q9NZ08,Q2T9J0,P28072,Q6NTF9,Q16740,P42892,P20618,P53634,O75844,O14773,Q8TCT9,P49720,Q96K76,P67812
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
128,245,10,16,287,154,35,170,47,49,52,302,62,63,192,328,87,319,235,354,254,241
|
319,1202,1206,87,2848,1476,1761,728,818,192,1345,1895,647,52,35,2328,2329,733,2335,737,63,2599,170,354,10,740,594,328,1782,128,241,665,1518,2619,2228,62,49,245,402,1664,302,287,1405,679,235,683,1548,687,952,2252,254,1690,961,2824,1177,2117,154,47,3145,3312,16,3250,514,3012
|
0.6987063152944422,0.10157608769830284,0.10157608769830284,1.7052535001830216,-0.5412682933157936,0.005872513874080369,-0.09094104587744528,0.3361888423900969,0.2897820267826493,1.046822951105993,0.053860976884978005,-0.13977468780074367,0.38234507015049096,2.431534530000306,3.0039248680970876,-0.28803660939734893,-0.28803660939734893,0.3361888423900969,-0.28803660939734893,0.3361888423900969,2.132393733047149,-0.388392317630512,1.1317712009042973,0.6542105287099975,6.0439644005275905,0.3361888423900969,0.4282542060735226,0.6987063152944422,-0.09094104587744528,1.381940746478781,0.8744716799879915,0.38234507015049096,0.005872513874080369,-0.388392317630512,-0.23831786606746352,2.245653162379946,2.5413946027810876,0.8744716799879915,0.6094870655900769,-0.04239342030431858,0.7429774213920438,0.7870267798407822,0.053860976884978005,0.38234507015049096,0.9178727874245445,0.38234507015049096,0.005872513874080369,0.38234507015049096,0.24312104666747653,-0.23831786606746352,0.8744716799879915,-0.04239342030431858,0.24312104666747653,-0.4899972174116964,0.14902186735214557,-0.18889877938207092,1.257715066848026,2.5777445433602932,-0.8553842121388305,-1.6881333429715428,5.023653846020728,-1.1804567452748522,0.5193447980380466,-0.6447419635510961
| 3,367
|
Intrinsic component of organelle membrane
| 47
| 111
| 3.261981
| 0.001106
|
Q9NQC3,Q9UH99,Q9BWH2,Q9NX63,Q9BTV4,Q9HC21,O60830,Q99595,Q14739,Q13505,P51572,Q9Y2R0,P13473,Q9Y282,O95470,Q9H490,O43752,Q9UG56,P20339,Q96S52,P56589,Q9UBM7,O14925,Q5XKP0,Q6NTF9,Q9BUR5,P42892,Q86Y82,P04439,O95070,Q969N2,O43505,Q9NRK6,Q15125,Q15629,Q9BUN8,O75844,Q8TB61,Q6ZRP7,Q8TCT9,Q10471,Q6UXV4,Q00325,Q15070,Q5J8M3,O15118,P01889
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
129,131,559,274,412,413,12,18,151,26,393,157,389,31,34,313,516,316,522,175,530,54,420,194,302,198,63,196,424,423,623,70,207,74,333,80,87,367,365,235,231,364,478,483,401,125,126
|
1868,2842,2296,420,3096,125,1324,2969,70,516,722,3351,12,3100,87,884,813,1097,1743,423,34,1880,727,126,424,1601,2585,389,2588,522,1349,1350,2329,2595,63,828,1014,393,530,913,1249,478,231,925,26,750,151,1261,753,483,74,1262,333,1809,2370,1812,401,2717,194,302,364,365,1404,1947,196,2814,2815,942,1162,2518,1952,367,235,1048,1548,623,1411,175,1058,18,3353,1697,412,80,198,559,630,313,1438,1439,413,1068,129,207,1993,274,1300,794,1302,1997,54,316,975,131,31,157,2429,2666,3012,801,871
|
-0.13977468780074367,-0.5412682933157936,-0.28803660939734893,0.5645328647779381,-0.8022645150247569,1.381940746478781,0.053860976884978005,-0.6447419635510961,2.0177872441211355,0.4739196680085796,0.3361888423900969,-2.962986316850552,5.531143228715627,-0.8022645150247569,1.7052535001830216,0.24312104666747653,0.2897820267826493,0.14902186735214557,-0.09094104587744528,0.5645328647779381,3.0039248680970876,-0.13977468780074367,0.3361888423900969,1.381940746478781,0.5645328647779381,-0.04239342030431858,-0.388392317630512,0.6094870655900769,-0.388392317630512,0.4739196680085796,0.053860976884978005,0.053860976884978005,-0.28803660939734893,-0.388392317630512,2.132393733047149,0.2897820267826493,0.19620224214011292,0.6094870655900769,0.4739196680085796,0.24312104666747653,0.10157608769830284,0.5193447980380466,0.9178727874245445,0.24312104666747653,3.578720683939666,0.3361888423900969,1.257715066848026,0.10157608769830284,0.3361888423900969,0.5193447980380466,1.9792784396533925,0.10157608769830284,0.6987063152944422,-0.09094104587744528,-0.28803660939734893,-0.09094104587744528,0.6094870655900769,-0.43903817143719953,1.046822951105993,0.7429774213920438,0.6542105287099975,0.6542105287099975,0.053860976884978005,-0.13977468780074367,1.046822951105993,-0.4899972174116964,-0.4899972174116964,0.24312104666747653,0.14902186735214557,-0.3380597911426015,-0.13977468780074367,0.6542105287099975,0.9178727874245445,0.19620224214011292,0.005872513874080369,0.4282542060735226,0.053860976884978005,1.1317712009042973,0.19620224214011292,4.731666431481315,-3.5466505530698798,-0.04239342030431858,0.6094870655900769,1.8628092769514064,1.046822951105993,0.4739196680085796,0.4282542060735226,0.7429774213920438,0.053860976884978005,0.053860976884978005,0.6094870655900769,0.19620224214011292,1.381940746478781,1.004045806677848,-0.13977468780074367,0.8308572620954069,0.10157608769830284,0.3361888423900969,0.10157608769830284,-0.13977468780074367,2.431534530000306,0.7429774213920438,0.24312104666747653,1.381940746478781,3.2104683932450104,1.257715066848026,-0.28803660939734893,-0.388392317630512,-0.6447419635510961,0.3361888423900969,0.2897820267826493
| 3,367
|
Receptor
| 8
| 28
| 3.213501
| 0.001311
|
Q9UQB8,Q9NR77,Q14108,A6NIH7,Q14118,Q9BUN8,P20645,Q8WTV0
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
0,67,164,9,263,80,23,25
|
9,1582,2969,876,882,886,1213,1751,1759,23,2334,2798,164,263,1806,2626,302,2243,1666,25,1957,80,970,1989,67,2835,2144,0
|
6.382598192426078,-0.04239342030431858,-0.6447419635510961,0.24312104666747653,0.24312104666747653,0.24312104666747653,0.10157608769830284,-0.09094104587744528,-0.09094104587744528,4.123694916854529,-0.28803660939734893,-0.4899972174116964,1.1739472326847418,0.8308572620954069,-0.09094104587744528,-0.388392317630512,0.7429774213920438,-0.23831786606746352,-0.04239342030431858,3.6115632124813404,-0.13977468780074367,1.8628092769514064,0.24312104666747653,-0.13977468780074367,2.0561416638490693,-0.4899972174116964,-0.18889877938207092,9.674117275578304
| 3,367
|
Outer membrane
| 30
| 83
| 3.211533
| 0.00132
|
Q9BWH2,Q9NX63,Q9NQZ5,Q5VT66,Q13505,Q9NVH0,Q99720,Q9NZJ7,Q9NVT9,Q9NS69,O43169,Q9UBM7,P45880,Q6SZW1,Q5XKP0,P09601,Q9BUR5,Q9BVC6,Q9NX47,O75323,Q96TC7,Q9BXR0,P50402,Q96RL7,P21796,Q8N2A8,Q86UT6,Q6UXV4,P30536,Q9NWX6
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
559,274,415,152,26,449,43,315,450,46,292,54,56,437,194,60,198,65,345,321,89,501,214,216,100,101,486,364,113,116
|
1459,1320,2439,292,989,1588,321,3100,1097,887,727,1595,2578,1599,60,2853,100,113,2188,2595,826,1005,56,214,828,1627,2347,3179,1646,26,2230,1390,2370,1812,152,194,1041,437,364,1399,2382,486,2815,942,1162,541,101,1277,1278,1827,1168,774,950,1418,216,89,962,1838,43,2895,198,65,559,560,501,3221,3118,415,46,449,1993,450,116,345,274,793,315,54,975,980,3347,801,2012
|
0.005872513874080369,0.053860976884978005,-0.3380597911426015,0.7429774213920438,0.19620224214011292,-0.04239342030431858,0.6987063152944422,-0.8022645150247569,0.14902186735214557,0.24312104666747653,0.3361888423900969,-0.04239342030431858,-0.388392317630512,-0.04239342030431858,2.283114015588119,-0.5412682933157936,1.6254733747117993,1.463832977402664,-0.23831786606746352,-0.388392317630512,0.2897820267826493,0.19620224214011292,2.394640025697565,0.961063282020524,0.2897820267826493,-0.04239342030431858,-0.28803660939734893,-0.9625354940644615,-0.04239342030431858,3.578720683939666,-0.23831786606746352,0.053860976884978005,-0.28803660939734893,-0.09094104587744528,1.257715066848026,1.046822951105993,0.19620224214011292,0.5645328647779381,0.6542105287099975,0.053860976884978005,-0.28803660939734893,0.5193447980380466,-0.4899972174116964,0.24312104666747653,0.14902186735214557,0.4739196680085796,1.6254733747117993,0.10157608769830284,0.10157608769830284,-0.09094104587744528,0.14902186735214557,0.3361888423900969,0.24312104666747653,0.053860976884978005,0.961063282020524,1.7052535001830216,0.24312104666747653,-0.09094104587744528,2.8638632384419833,-0.5412682933157936,1.046822951105993,2.0943433015075343,0.4739196680085796,0.4739196680085796,0.5193447980380466,-1.070895711677453,-0.8022645150247569,0.6094870655900769,2.7575257190991964,0.5645328647779381,-0.13977468780074367,0.5645328647779381,1.463832977402664,0.6987063152944422,0.8308572620954069,0.3361888423900969,0.7429774213920438,2.431534530000306,0.24312104666747653,0.24312104666747653,-2.710654339272441,0.3361888423900969,-0.13977468780074367
| 3,367
|
Receptor
| 13
| 35
| 3.083
| 0.002049
|
P30825,P55899,Q9Y2I1,Q14108,O15173,O15031,Q99720,Q14118,Q9NS69,P20645,Q14739,Q8WTV0,O15118
|
Functions
|
Protein Atlas Molecular function
|
protein_atlas_molecular_function
|
212,180,132,164,189,103,43,263,46,23,151,25,125
|
1459,1580,103,125,189,1472,1751,1475,1754,2580,2035,3025,1759,728,23,3176,212,825,180,3268,834,164,263,151,755,1532,25,953,1838,43,46,132,1078,1729,347
|
0.005872513874080369,-0.04239342030431858,1.5450050959353323,1.381940746478781,1.046822951105993,0.005872513874080369,-0.09094104587744528,0.005872513874080369,-0.09094104587744528,-0.388392317630512,-0.18889877938207092,-0.6969423099361801,-0.09094104587744528,0.3361888423900969,4.123694916854529,-0.9625354940644615,0.961063282020524,0.2897820267826493,1.0893972532895093,-1.2912106707426125,0.2897820267826493,1.1739472326847418,0.8308572620954069,1.257715066848026,0.3361888423900969,0.005872513874080369,3.6115632124813404,0.24312104666747653,-0.09094104587744528,2.8638632384419833,2.7575257190991964,1.381940746478781,0.19620224214011292,-0.04239342030431858,0.6987063152944422
| 3,367
|
Peptidase activity
| 30
| 118
| 3.077972
| 0.002084
|
P60900,Q4J6C6,Q9NUQ7,P42785,P49721,Q9UPU5,Q9UIQ6,Q70CQ2,Q9BYT8,Q9HB40,P55786,P28074,Q9NZ08,P48147,Q2T9J0,P28072,P10619,Q6NTF9,Q16740,P42892,P20618,P53634,O75844,O14773,Q99496,Q8TCT9,P49720,Q96K76,P67812,P83111
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
128,245,130,3,10,16,19,287,154,28,159,35,47,170,49,52,61,302,62,63,192,328,87,319,369,235,354,254,241,243
|
1731,2437,319,874,1202,1206,87,644,2307,383,888,1472,2848,1476,2917,61,1224,1761,728,818,192,1345,1895,647,52,35,2778,2328,2329,901,733,2335,737,3,63,2599,170,354,10,3226,1244,740,594,1365,328,1782,159,128,596,241,2927,243,3332,665,2707,1518,2619,2228,1387,62,49,245,1659,402,1664,1154,1535,302,1272,287,2511,1819,2812,1405,2991,679,235,683,1548,2393,2394,687,952,2252,624,3202,851,2993,254,959,1690,961,2824,369,2951,1177,2117,695,154,785,2411,786,1299,28,1186,2414,130,701,47,3145,3312,19,457,16,3250,514,3012,2755
|
-0.09094104587744528,-0.3380597911426015,0.6987063152944422,0.24312104666747653,0.10157608769830284,0.10157608769830284,1.7052535001830216,0.38234507015049096,-0.28803660939734893,0.6094870655900769,0.24312104666747653,0.005872513874080369,-0.5412682933157936,0.005872513874080369,-0.5928502525010018,2.283114015588119,0.10157608769830284,-0.09094104587744528,0.3361888423900969,0.2897820267826493,1.046822951105993,0.053860976884978005,-0.13977468780074367,0.38234507015049096,2.431534530000306,3.0039248680970876,-0.4899972174116964,-0.28803660939734893,-0.28803660939734893,0.24312104666747653,0.3361888423900969,-0.28803660939734893,0.3361888423900969,7.767211111294991,2.132393733047149,-0.388392317630512,1.1317712009042973,0.6542105287099975,6.0439644005275905,-1.1255266262233685,0.10157608769830284,0.3361888423900969,0.4282542060735226,0.053860976884978005,0.6987063152944422,-0.09094104587744528,1.2159277397438069,1.381940746478781,0.4282542060735226,0.8744716799879915,-0.5928502525010018,0.8744716799879915,-2.0992610771115365,0.38234507015049096,-0.43903817143719953,0.005872513874080369,-0.388392317630512,-0.23831786606746352,0.053860976884978005,2.245653162379946,2.5413946027810876,0.8744716799879915,-0.04239342030431858,0.6094870655900769,-0.04239342030431858,0.14902186735214557,0.005872513874080369,0.7429774213920438,0.10157608769830284,0.7870267798407822,-0.3380597911426015,-0.09094104587744528,-0.4899972174116964,0.053860976884978005,-0.6447419635510961,0.38234507015049096,0.9178727874245445,0.38234507015049096,0.005872513874080369,-0.28803660939734893,-0.28803660939734893,0.38234507015049096,0.24312104666747653,-0.23831786606746352,0.4282542060735226,-1.0165649980725264,0.2897820267826493,-0.6447419635510961,0.8744716799879915,0.24312104666747653,-0.04239342030431858,0.24312104666747653,-0.4899972174116964,0.6542105287099975,-0.5928502525010018,0.14902186735214557,-0.18889877938207092,0.38234507015049096,1.257715066848026,0.3361888423900969,-0.28803660939734893,0.3361888423900969,0.10157608769830284,3.4129471399409548,0.14902186735214557,-0.28803660939734893,1.381940746478781,0.38234507015049096,2.5777445433602932,-0.8553842121388305,-1.6881333429715428,4.4014392320994515,0.5645328647779381,5.023653846020728,-1.1804567452748522,0.5193447980380466,-0.6447419635510961,-0.43903817143719953
| 3,367
|
Regulation of blood pressure
| 6
| 17
| 3.023149
| 0.002502
|
P42785,P80404,Q9NZ08,Q9UIQ6,Q9HB40,P09601
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
3,36,47,19,28,60
|
2447,1101,1597,60,2452,2588,3,63,3033,1624,36,2497,2650,28,47,19,3172
|
-0.3380597911426015,0.14902186735214557,-0.04239342030431858,2.283114015588119,-0.3380597911426015,-0.388392317630512,7.767211111294991,2.132393733047149,-0.6969423099361801,-0.04239342030431858,2.969090607110795,-0.3380597911426015,-0.388392317630512,3.4129471399409548,2.5777445433602932,4.4014392320994515,-0.908808220790615
| 3,367
|
Intrinsic component of endoplasmic reticulum membrane
| 16
| 48
| 3.009624
| 0.002616
|
Q9NQC3,O95470,Q9H490,Q8TCT9,Q15125,Q96S52,Q15629,Q9BUN8,Q8TB61,Q9UBM7,Q6NTF9,O75844,Q5J8M3,P51572,P01889,Q9Y282
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
129,34,313,235,74,175,333,80,367,54,302,87,401,393,126,31
|
1868,2296,3096,2969,87,813,34,126,424,1601,1349,1350,2329,393,913,1249,925,750,1261,753,74,333,401,302,1404,1947,2814,2518,367,235,1548,623,1411,175,1058,1697,80,313,1068,129,1300,794,1302,1997,54,31,2666,871
|
-0.13977468780074367,-0.28803660939734893,-0.8022645150247569,-0.6447419635510961,1.7052535001830216,0.2897820267826493,3.0039248680970876,1.381940746478781,0.5645328647779381,-0.04239342030431858,0.053860976884978005,0.053860976884978005,-0.28803660939734893,0.6094870655900769,0.24312104666747653,0.10157608769830284,0.24312104666747653,0.3361888423900969,0.10157608769830284,0.3361888423900969,1.9792784396533925,0.6987063152944422,0.6094870655900769,0.7429774213920438,0.053860976884978005,-0.13977468780074367,-0.4899972174116964,-0.3380597911426015,0.6542105287099975,0.9178727874245445,0.005872513874080369,0.4282542060735226,0.053860976884978005,1.1317712009042973,0.19620224214011292,-0.04239342030431858,1.8628092769514064,0.7429774213920438,0.19620224214011292,1.381940746478781,0.10157608769830284,0.3361888423900969,0.10157608769830284,-0.13977468780074367,2.431534530000306,3.2104683932450104,-0.388392317630512,0.2897820267826493
| 3,367
|
Ion transmembrane transporter activity
| 27
| 80
| 3.005802
| 0.002649
|
P51798,O43772,Q9HC21,Q9C0H2,P11166,O75964,O95202,Q70HW3,P56385,Q9HD20,P45880,P36542,Q02978,P61421,Q9BVC6,Q8TB61,Q6N075,P30825,Q9Y696,P21796,P21283,Q9UI12,P12236,Q9H2D1,Q9UDW1,Q00325,P21281
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
475,2,413,145,388,33,519,45,529,51,56,297,533,532,65,367,363,212,237,100,588,372,470,105,118,478,121
|
2295,2016,1201,2,722,1095,584,33,519,1880,1471,1597,1102,1334,2168,2450,890,1336,2849,2319,388,2585,470,1000,1226,2588,2322,121,588,100,1347,2777,212,1615,297,1905,1492,2978,56,3191,2338,475,1917,911,2208,742,529,532,1249,478,533,3156,2229,1033,755,363,938,1271,1397,45,1952,367,953,3163,1693,65,145,2898,105,3281,1438,413,51,1998,118,372,867,980,2006,237
|
-0.28803660939734893,-0.18889877938207092,0.10157608769830284,8.462226464311355,0.3361888423900969,0.14902186735214557,0.4282542060735226,3.0386401585275027,0.4739196680085796,-0.13977468780074367,0.005872513874080369,-0.04239342030431858,0.14902186735214557,0.053860976884978005,-0.23831786606746352,-0.3380597911426015,0.24312104666747653,0.053860976884978005,-0.5412682933157936,-0.28803660939734893,0.6094870655900769,-0.388392317630512,0.5193447980380466,0.19620224214011292,0.10157608769830284,-0.388392317630512,-0.28803660939734893,1.422977916752635,0.4282542060735226,1.6254733747117993,0.053860976884978005,-0.4899972174116964,0.961063282020524,-0.04239342030431858,0.7429774213920438,-0.13977468780074367,0.005872513874080369,-0.6447419635510961,2.394640025697565,-1.0165649980725264,-0.28803660939734893,0.5193447980380466,-0.13977468780074367,0.24312104666747653,-0.23831786606746352,0.3361888423900969,0.4739196680085796,0.4739196680085796,0.10157608769830284,0.5193447980380466,0.4739196680085796,-0.908808220790615,-0.23831786606746352,0.19620224214011292,0.3361888423900969,0.6542105287099975,0.24312104666747653,0.10157608769830284,0.053860976884978005,2.7575257190991964,-0.13977468780074367,0.6542105287099975,0.24312104666747653,-0.908808220790615,-0.04239342030431858,2.0943433015075343,1.2993115136492674,-0.5412682933157936,1.5450050959353323,-1.3470325431471153,0.053860976884978005,0.6094870655900769,2.5049104893301823,-0.13977468780074367,1.463832977402664,0.6542105287099975,0.2897820267826493,0.24312104666747653,-0.13977468780074367,0.9178727874245445
| 3,367
|
Serine hydrolase activity
| 11
| 19
| 2.927868
| 0.003413
|
Q4J6C6,P42785,P48147,Q2T9J0,P53634,O14773,Q6NTF9,P10619,Q9HB40,P67812,Q16740
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
245,3,170,49,328,319,302,61,28,241,62
|
319,644,61,1761,2328,733,3,170,1365,328,241,62,49,245,402,302,2812,785,28
|
0.6987063152944422,0.38234507015049096,2.283114015588119,-0.09094104587744528,-0.28803660939734893,0.3361888423900969,7.767211111294991,1.1317712009042973,0.053860976884978005,0.6987063152944422,0.8744716799879915,2.245653162379946,2.5413946027810876,0.8744716799879915,0.6094870655900769,0.7429774213920438,-0.4899972174116964,0.3361888423900969,3.4129471399409548
| 3,367
|
Glycerophospholipid biosynthesis
| 9
| 31
| 2.900801
| 0.003722
|
Q96N66,Q8NCC3,Q8IV08,Q9NPH0,Q8N2A8,Q9NQZ5,Q9UG56,Q92604,P35790
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
337,4,37,38,101,415,316,172,213
|
807,1199,2157,385,1470,1003,213,1233,1359,1911,909,2347,1636,1812,1945,37,101,616,1278,4,2246,2249,172,337,2889,2117,963,1296,38,415,316
|
0.2897820267826493,0.10157608769830284,-0.23831786606746352,0.6094870655900769,0.005872513874080369,0.19620224214011292,0.961063282020524,0.10157608769830284,0.053860976884978005,-0.13977468780074367,0.24312104666747653,-0.28803660939734893,-0.04239342030431858,-0.09094104587744528,-0.13977468780074367,2.969090607110795,1.6254733747117993,0.4282542060735226,0.10157608769830284,7.298411945543759,-0.23831786606746352,-0.23831786606746352,1.1317712009042973,0.6987063152944422,-0.5412682933157936,-0.18889877938207092,0.24312104666747653,0.10157608769830284,2.969090607110795,0.6094870655900769,0.7429774213920438
| 3,367
|
Predicted secreted proteins
| 13
| 48
| 2.89766
| 0.00376
|
Q15165,Q9UM22,P05067,P80303,Q9BUR5,Q9NZ08,P43490,Q9UMX5,O75718,P61916,P30740,Q9HB40,Q02818
|
Functions
|
Protein Atlas Protein class
|
protein_atlas_protein_class
|
1,68,190,8,198,47,203,84,201,149,238,28,30
|
2014,1580,517,3272,201,2774,1472,1882,190,1752,2168,2317,2973,521,728,1342,1608,895,238,203,2697,1780,1631,149,8,2927,30,600,664,284,2616,834,1,3184,3323,2643,3206,1293,198,784,2411,2651,28,47,3324,68,84,2666
|
-0.18889877938207092,-0.04239342030431858,0.4739196680085796,-1.3470325431471153,1.004045806677848,-0.4899972174116964,0.005872513874080369,-0.13977468780074367,1.046822951105993,-0.09094104587744528,-0.23831786606746352,-0.28803660939734893,-0.6447419635510961,0.4739196680085796,0.3361888423900969,0.053860976884978005,-0.04239342030431858,0.24312104666747653,0.8744716799879915,1.004045806677848,-0.43903817143719953,-0.09094104587744528,-0.04239342030431858,1.257715066848026,6.4338683401100525,-0.5928502525010018,3.2104683932450104,0.4282542060735226,0.38234507015049096,0.7870267798407822,-0.388392317630512,0.2897820267826493,9.185425981910969,-0.9625354940644615,-1.8626090534362079,-0.388392317630512,-1.0165649980725264,0.10157608769830284,1.046822951105993,0.3361888423900969,-0.28803660939734893,-0.388392317630512,3.4129471399409548,2.5777445433602932,-1.8626090534362079,2.0561416638490693,1.7843606013886042,-0.388392317630512
| 3,367
|
serine protease
| 9
| 18
| 2.885641
| 0.003906
|
Q4J6C6,P42785,P10619,P48147,Q2T9J0,O14773,Q9HB40,P67812,Q16740
|
Functions
|
Panther Protein class
|
panther_protein_class
|
245,3,61,170,49,319,28,241,62
|
319,61,1478,1761,2328,733,3,170,241,62,49,245,2812,366,948,785,28,2141
|
0.6987063152944422,2.283114015588119,0.005872513874080369,-0.09094104587744528,-0.28803660939734893,0.3361888423900969,7.767211111294991,1.1317712009042973,0.8744716799879915,2.245653162379946,2.5413946027810876,0.8744716799879915,-0.4899972174116964,0.6542105287099975,0.24312104666747653,0.3361888423900969,3.4129471399409548,-0.18889877938207092
| 3,367
|
Tetratricopeptide-like helical domain superfamily [IPR011990]
| 14
| 91
| 2.820377
| 0.004797
|
Q6ZXV5,O75153,A0AVF1,Q32P28,Q9Y262,Q5R3I4,Q9H7B4,P13674,Q86US8,O75718,Q96TC7,O00411,Q6DKK2,Q6PGP7
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
267,5,133,11,111,13,14,108,306,201,89,119,94,303
|
133,1730,1319,119,2670,1198,1088,3122,875,2764,5,201,813,1878,1097,2574,1746,108,391,2187,1617,826,1005,2863,1241,2698,1499,2479,920,1791,2487,1642,1254,1136,833,1799,1519,750,1385,2988,1261,1524,3130,1390,11,13,935,94,2506,436,1156,303,267,1042,335,2096,306,3315,615,685,1549,2948,689,409,849,958,89,2529,2400,2260,3348,1983,1846,2409,2272,2739,14,1563,1565,3210,1193,868,1308,1999,3211,111,2291,1572,1456,804,1576
|
1.3407193358749927,-0.09094104587744528,0.053860976884978005,1.422977916752635,-0.43903817143719953,0.10157608769830284,0.14902186735214557,-0.8553842121388305,0.24312104666747653,-0.4899972174116964,6.861258766582419,1.004045806677848,0.2897820267826493,-0.13977468780074367,0.14902186735214557,-0.388392317630512,-0.09094104587744528,1.5045080195895706,0.6094870655900769,-0.23831786606746352,-0.04239342030431858,0.2897820267826493,0.19620224214011292,-0.5412682933157936,0.10157608769830284,-0.43903817143719953,0.005872513874080369,-0.3380597911426015,0.24312104666747653,-0.09094104587744528,-0.3380597911426015,-0.04239342030431858,0.10157608769830284,0.14902186735214557,0.2897820267826493,-0.09094104587744528,0.005872513874080369,0.3361888423900969,0.053860976884978005,-0.6447419635510961,0.10157608769830284,0.005872513874080369,-0.8553842121388305,0.053860976884978005,6.0175178435563295,5.47584118755579,0.24312104666747653,1.6654484983059537,-0.3380597911426015,0.5645328647779381,0.14902186735214557,0.7429774213920438,0.8308572620954069,0.19620224214011292,0.6987063152944422,-0.18889877938207092,0.7429774213920438,-1.7460032195660424,0.4282542060735226,0.38234507015049096,0.005872513874080369,-0.5928502525010018,0.38234507015049096,0.6094870655900769,0.2897820267826493,0.24312104666747653,1.7052535001830216,-0.3380597911426015,-0.28803660939734893,-0.23831786606746352,-2.836270967644657,-0.13977468780074367,-0.09094104587744528,-0.28803660939734893,-0.23831786606746352,-0.43903817143719953,5.364443360547954,0.005872513874080369,0.005872513874080369,-1.0165649980725264,0.14902186735214557,0.2897820267826493,0.10157608769830284,-0.13977468780074367,-1.0165649980725264,1.5045080195895706,-0.23831786606746352,0.005872513874080369,0.053860976884978005,0.3361888423900969,0.005872513874080369
| 3,367
|
Serine protease
| 8
| 30
| 2.809535
| 0.004961
|
P42785,P48147,Q2T9J0,O14773,P34913,P10619,Q9HB40,P67812
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
3,170,49,319,179,61,28,241
|
2013,319,61,1761,2328,179,733,3,170,1365,1919,915,241,2616,2083,1655,49,2812,486,366,948,1831,954,1054,785,28,2136,2141,1863,575
|
-0.18889877938207092,0.6987063152944422,2.283114015588119,-0.09094104587744528,-0.28803660939734893,1.0893972532895093,0.3361888423900969,7.767211111294991,1.1317712009042973,0.053860976884978005,-0.13977468780074367,0.24312104666747653,0.8744716799879915,-0.388392317630512,-0.18889877938207092,-0.04239342030431858,2.5413946027810876,-0.4899972174116964,0.5193447980380466,0.6542105287099975,0.24312104666747653,-0.09094104587744528,0.24312104666747653,0.19620224214011292,0.3361888423900969,3.4129471399409548,-0.18889877938207092,-0.18889877938207092,-0.09094104587744528,0.4739196680085796
| 3,367
|
Endoplasmic reticulum golgi intermediate compartment
| 13
| 45
| 2.791496
| 0.005247
|
Q13190,P80303,Q5VYK3,Q08379,Q96GC9,P07237,P53634,Q12907,O15260,P51572,Q8N511,Q02818,Q9Y282
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
396,8,41,75,174,323,328,150,379,393,95,30,31
|
1324,379,579,2969,1466,423,323,2317,3176,1349,2977,1777,1012,2200,393,2475,328,1781,8,30,75,601,150,396,752,2082,1263,41,1540,95,2820,2643,1416,174,1422,558,1062,636,2548,2424,1312,31,3008,870,1315
|
0.053860976884978005,0.6094870655900769,0.4282542060735226,-0.6447419635510961,0.005872513874080369,0.5645328647779381,0.6987063152944422,-0.28803660939734893,-0.9625354940644615,0.053860976884978005,-0.6447419635510961,-0.09094104587744528,0.19620224214011292,-0.23831786606746352,0.6094870655900769,-0.3380597911426015,0.6987063152944422,-0.09094104587744528,6.4338683401100525,3.2104683932450104,1.9017911284204507,0.4282542060735226,1.257715066848026,0.6094870655900769,0.3361888423900969,-0.18889877938207092,0.10157608769830284,2.899060884241353,0.005872513874080369,1.6654484983059537,-0.4899972174116964,-0.388392317630512,0.053860976884978005,1.1317712009042973,0.053860976884978005,0.4739196680085796,0.19620224214011292,0.4282542060735226,-0.3380597911426015,-0.28803660939734893,0.10157608769830284,3.2104683932450104,-0.6447419635510961,0.2897820267826493,0.10157608769830284
| 3,367
|
Molecular transducer activity
| 8
| 30
| 2.786485
| 0.005328
|
Q14108,O15031,Q99720,Q9BUN8,P30536,P20645,Q8WTV0,O15118
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
164,103,43,80,113,23,25,125
|
1580,103,125,189,2765,1751,1759,23,113,904,2334,1239,832,3268,834,164,333,755,2625,1532,2243,25,953,1058,43,80,2546,1997,1305,2555
|
-0.04239342030431858,1.5450050959353323,1.381940746478781,1.046822951105993,-0.4899972174116964,-0.09094104587744528,-0.09094104587744528,4.123694916854529,1.463832977402664,0.24312104666747653,-0.28803660939734893,0.10157608769830284,0.2897820267826493,-1.2912106707426125,0.2897820267826493,1.1739472326847418,0.6987063152944422,0.3361888423900969,-0.388392317630512,0.005872513874080369,-0.23831786606746352,3.6115632124813404,0.24312104666747653,0.19620224214011292,2.8638632384419833,1.8628092769514064,-0.3380597911426015,-0.13977468780074367,0.10157608769830284,-0.3380597911426015
| 3,367
|
Steroid binding
| 8
| 22
| 2.683626
| 0.007283
|
P04062,Q14108,P21796,O15173,P30536,P61916,P45880,O15118
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
99,164,100,189,113,149,56,125
|
1459,125,189,885,99,1597,2450,100,1110,1607,113,429,1358,56,149,164,1145,1175,2532,1296,2535,341
|
0.005872513874080369,1.381940746478781,1.046822951105993,0.24312104666747653,1.6254733747117993,-0.04239342030431858,-0.3380597911426015,1.6254733747117993,0.14902186735214557,-0.04239342030431858,1.463832977402664,0.5645328647779381,0.053860976884978005,2.394640025697565,1.257715066848026,1.1739472326847418,0.14902186735214557,0.14902186735214557,-0.3380597911426015,0.10157608769830284,-0.3380597911426015,0.6987063152944422
| 3,367
|
Mitochondrial transport
| 18
| 77
| 2.675496
| 0.007462
|
Q9Y276,O75964,O43772,P55786,P36542,Q99496,Q9NRK6,O60830,Q9NS69,O14925,P30536,Q99595,P23786,P45880,P51572,Q96EK5,Q5JRX3,Q9P0J0
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
510,33,2,159,297,369,207,12,46,420,113,18,82,56,393,409,402,220
|
1730,808,420,719,2,12,3100,1206,584,33,1097,3103,1212,2310,1214,727,997,1102,1334,2032,1599,1337,2585,1003,82,1347,2777,2591,3063,113,2331,297,2979,56,2338,1010,1777,3033,1120,828,393,1627,159,742,529,1924,665,2986,1145,483,1390,609,1812,402,938,1670,942,1162,2250,409,960,369,18,2999,2538,207,46,220,2140,1998,867,2283,510,3347,799,801,1575
|
-0.09094104587744528,0.2897820267826493,0.5645328647779381,0.3361888423900969,8.462226464311355,5.531143228715627,-0.8022645150247569,0.10157608769830284,0.4282542060735226,3.0386401585275027,0.14902186735214557,-0.8022645150247569,0.10157608769830284,-0.28803660939734893,0.10157608769830284,0.3361888423900969,0.19620224214011292,0.14902186735214557,0.053860976884978005,-0.18889877938207092,-0.04239342030431858,0.053860976884978005,-0.388392317630512,0.19620224214011292,1.7843606013886042,0.053860976884978005,-0.4899972174116964,-0.388392317630512,-0.7494501896778172,1.463832977402664,-0.28803660939734893,0.7429774213920438,-0.6447419635510961,2.394640025697565,-0.28803660939734893,0.19620224214011292,-0.09094104587744528,-0.6969423099361801,0.14902186735214557,0.2897820267826493,0.6094870655900769,-0.04239342030431858,1.2159277397438069,0.3361888423900969,0.4739196680085796,-0.13977468780074367,0.38234507015049096,-0.6447419635510961,0.14902186735214557,0.5193447980380466,0.053860976884978005,0.4282542060735226,-0.09094104587744528,0.6094870655900769,0.24312104666747653,-0.04239342030431858,0.24312104666747653,0.14902186735214557,-0.23831786606746352,0.6094870655900769,0.24312104666747653,0.6542105287099975,4.731666431481315,-0.6447419635510961,-0.3380597911426015,1.004045806677848,2.7575257190991964,0.961063282020524,-0.18889877938207092,-0.13977468780074367,0.2897820267826493,-0.23831786606746352,0.5193447980380466,-2.710654339272441,0.3361888423900969,0.3361888423900969,0.005872513874080369
| 3,367
|
Circulatory system process
| 15
| 70
| 2.594891
| 0.009462
|
P30825,Q6PI78,P42785,P80404,Q9HB40,Q9NZ08,P46734,Q9UIQ6,Q99996,O75844,P78417,Q16625,Q9NRY4,P09601,P42892
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
212,195,3,36,28,47,260,19,83,87,242,301,156,60,63
|
1320,873,2016,517,3153,1468,87,1742,2447,2774,1595,1472,1101,322,1597,2451,60,2318,388,2582,2452,3224,3291,1226,2588,2176,2857,2185,212,2978,3066,826,3,63,260,1010,592,3033,1624,911,2208,1125,2064,242,36,3109,1253,3268,2708,924,667,2076,1142,2497,2230,755,301,1271,195,616,2395,496,1693,83,2650,28,156,47,19,3172
|
0.053860976884978005,0.24312104666747653,-0.18889877938207092,0.4739196680085796,-0.908808220790615,0.005872513874080369,1.7052535001830216,-0.09094104587744528,-0.3380597911426015,-0.4899972174116964,-0.04239342030431858,0.005872513874080369,0.14902186735214557,0.6987063152944422,-0.04239342030431858,-0.3380597911426015,2.283114015588119,-0.28803660939734893,0.6094870655900769,-0.388392317630512,-0.3380597911426015,-1.1255266262233685,-1.4595613570006674,0.10157608769830284,-0.388392317630512,-0.23831786606746352,-0.5412682933157936,-0.23831786606746352,0.961063282020524,-0.6447419635510961,-0.7494501896778172,0.2897820267826493,7.767211111294991,2.132393733047149,0.8308572620954069,0.19620224214011292,0.4282542060735226,-0.6969423099361801,-0.04239342030431858,0.24312104666747653,-0.23831786606746352,0.14902186735214557,-0.18889877938207092,0.8744716799879915,2.969090607110795,-0.8022645150247569,0.10157608769830284,-1.2912106707426125,-0.43903817143719953,0.24312104666747653,0.38234507015049096,-0.18889877938207092,0.14902186735214557,-0.3380597911426015,-0.23831786606746352,0.3361888423900969,0.7429774213920438,0.10157608769830284,1.046822951105993,0.4282542060735226,-0.28803660939734893,0.5193447980380466,-0.04239342030431858,1.7843606013886042,-0.388392317630512,3.4129471399409548,1.257715066848026,2.5777445433602932,4.4014392320994515,-0.908808220790615
| 3,367
|
Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen
| 6
| 31
| 2.587892
| 0.009657
|
Q32P28,Q16850,P13674,P30519,Q9NVH6,P09601
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
11,76,108,53,200,60
|
1321,2296,3122,1587,517,1467,2312,323,60,108,1340,1900,53,2465,659,1927,1254,2621,193,76,11,2243,675,1157,613,1820,626,2270,200,1077,1455
|
0.053860976884978005,-0.28803660939734893,-0.8553842121388305,-0.04239342030431858,0.4739196680085796,0.005872513874080369,-0.28803660939734893,0.6987063152944422,2.283114015588119,1.5045080195895706,0.053860976884978005,-0.13977468780074367,2.431534530000306,-0.3380597911426015,0.38234507015049096,-0.13977468780074367,0.10157608769830284,-0.388392317630512,1.046822951105993,1.9017911284204507,6.0175178435563295,-0.23831786606746352,0.38234507015049096,0.14902186735214557,0.4282542060735226,-0.09094104587744528,0.4282542060735226,-0.23831786606746352,1.046822951105993,0.19620224214011292,0.053860976884978005
| 3,367
|
Glycerolipid biosynthetic process
| 11
| 47
| 2.571815
| 0.010117
|
Q96Q15,Q96N66,Q8NCC3,Q9H490,Q9NPH0,Q9UG56,Q96S52,Q92604,Q8WTV0,P42356,P35790
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
64,337,4,313,38,316,175,172,25,239,213
|
873,807,1199,2673,3055,887,385,2311,1470,818,3225,2188,213,239,1911,1926,665,835,606,2086,674,335,1945,4,2246,3136,25,2249,1048,172,1548,623,1413,337,64,175,2889,555,963,2402,1844,2405,313,38,2543,316,1312
|
0.24312104666747653,0.2897820267826493,0.10157608769830284,-0.43903817143719953,-0.7494501896778172,0.24312104666747653,0.6094870655900769,-0.28803660939734893,0.005872513874080369,0.2897820267826493,-1.1255266262233685,-0.23831786606746352,0.961063282020524,0.8744716799879915,-0.13977468780074367,-0.13977468780074367,0.38234507015049096,0.2897820267826493,0.4282542060735226,-0.18889877938207092,0.38234507015049096,0.6987063152944422,-0.13977468780074367,7.298411945543759,-0.23831786606746352,-0.8553842121388305,3.6115632124813404,-0.23831786606746352,0.19620224214011292,1.1317712009042973,0.005872513874080369,0.4282542060735226,0.053860976884978005,0.6987063152944422,2.132393733047149,1.1317712009042973,-0.5412682933157936,0.4739196680085796,0.24312104666747653,-0.28803660939734893,-0.09094104587744528,-0.28803660939734893,0.7429774213920438,2.969090607110795,-0.3380597911426015,0.7429774213920438,0.10157608769830284
| 3,367
|
Proteasome degradation
| 8
| 42
| 2.556273
| 0.01058
|
P60900,P28074,P16104,P20618,P49721,P28072,P61289,P01889
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
128,35,158,192,10,52,283,126
|
1319,2436,2567,875,2846,126,424,1883,815,1601,158,1343,192,1486,2458,2179,2041,1895,1771,647,52,35,2193,2197,908,1011,354,10,1244,2699,128,283,1504,2609,2065,1792,1797,1524,2824,2258,638,2426
|
0.053860976884978005,-0.3380597911426015,-0.388392317630512,0.24312104666747653,-0.5412682933157936,1.381940746478781,0.5645328647779381,-0.13977468780074367,0.2897820267826493,-0.04239342030431858,1.2159277397438069,0.053860976884978005,1.046822951105993,0.005872513874080369,-0.3380597911426015,-0.23831786606746352,-0.18889877938207092,-0.13977468780074367,-0.09094104587744528,0.38234507015049096,2.431534530000306,3.0039248680970876,-0.23831786606746352,-0.23831786606746352,0.24312104666747653,0.19620224214011292,0.6542105287099975,6.0439644005275905,0.10157608769830284,-0.43903817143719953,1.381940746478781,0.7870267798407822,0.005872513874080369,-0.388392317630512,-0.18889877938207092,-0.09094104587744528,-0.09094104587744528,0.005872513874080369,-0.4899972174116964,-0.23831786606746352,0.4282542060735226,-0.28803660939734893
| 3,367
|
Mitochondrial transmembrane transport
| 6
| 45
| 2.549779
| 0.010779
|
O75964,O43772,P21796,O60830,Q99595,P23786
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
33,2,100,12,18,82
|
420,719,2,12,2910,1206,1095,584,33,1097,519,1880,1214,727,1102,1334,1337,2585,470,100,82,1347,2777,297,2338,828,1917,742,529,478,609,3288,1952,2391,2250,18,3353,500,105,3281,1438,2538,867,2283,3012
|
0.5645328647779381,0.3361888423900969,8.462226464311355,5.531143228715627,-0.5928502525010018,0.10157608769830284,0.14902186735214557,0.4282542060735226,3.0386401585275027,0.14902186735214557,0.4739196680085796,-0.13977468780074367,0.10157608769830284,0.3361888423900969,0.14902186735214557,0.053860976884978005,0.053860976884978005,-0.388392317630512,0.5193447980380466,1.6254733747117993,1.7843606013886042,0.053860976884978005,-0.4899972174116964,0.7429774213920438,-0.28803660939734893,0.2897820267826493,-0.13977468780074367,0.3361888423900969,0.4739196680085796,0.5193447980380466,0.4282542060735226,-1.403149751562867,-0.13977468780074367,-0.28803660939734893,-0.23831786606746352,4.731666431481315,-3.5466505530698798,0.5193447980380466,1.5450050959353323,-1.3470325431471153,0.053860976884978005,-0.3380597911426015,0.2897820267826493,-0.23831786606746352,-0.6447419635510961
| 3,367
|
Regulation of nervous system process
| 6
| 14
| 2.534646
| 0.011256
|
Q9UQB8,P04062,P80404,P05067,Q14118,Q99996
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
0,99,36,190,263,83
|
3153,1095,99,190,2779,328,36,1793,606,263,1937,83,979,0
|
-0.908808220790615,0.14902186735214557,1.6254733747117993,1.046822951105993,-0.4899972174116964,0.6987063152944422,2.969090607110795,-0.09094104587744528,0.4282542060735226,0.8308572620954069,-0.13977468780074367,1.7843606013886042,0.24312104666747653,9.674117275578304
| 3,367
|
Exopeptidase activity
| 6
| 31
| 2.53159
| 0.011355
|
P42785,Q9NZ08,Q9UIQ6,O75844,P10619,Q9HB40
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
3,47,19,87,61,28
|
319,87,644,1472,2917,61,1224,2778,2328,901,3,3226,328,159,2707,2619,2812,2991,2393,624,3202,959,2117,785,2411,28,1186,2414,701,47,19
|
0.6987063152944422,1.7052535001830216,0.38234507015049096,0.005872513874080369,-0.5928502525010018,2.283114015588119,0.10157608769830284,-0.4899972174116964,-0.28803660939734893,0.24312104666747653,7.767211111294991,-1.1255266262233685,0.6987063152944422,1.2159277397438069,-0.43903817143719953,-0.388392317630512,-0.4899972174116964,-0.6447419635510961,-0.28803660939734893,0.4282542060735226,-1.0165649980725264,0.24312104666747653,-0.18889877938207092,0.3361888423900969,-0.28803660939734893,3.4129471399409548,0.14902186735214557,-0.28803660939734893,0.38234507015049096,2.5777445433602932,4.4014392320994515
| 3,367
|
Synaptic membrane
| 6
| 43
| 2.505261
| 0.012236
|
Q9UQB8,Q99720,Q14118,Q12846,Q99996,Q9UQ16
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
0,43,263,114,83,187
|
2758,1580,2018,2845,580,1874,1751,1886,1219,1220,2680,294,2588,1350,898,1117,525,1914,1364,1793,114,3072,1138,606,263,1802,1937,2085,1827,683,1412,1682,443,43,83,2263,2402,2541,2552,187,0,708,800
|
-0.4899972174116964,-0.04239342030431858,-0.18889877938207092,-0.5412682933157936,0.4282542060735226,-0.13977468780074367,-0.09094104587744528,-0.13977468780074367,0.10157608769830284,0.10157608769830284,-0.43903817143719953,0.7429774213920438,-0.388392317630512,0.053860976884978005,0.24312104666747653,0.14902186735214557,0.4739196680085796,-0.13977468780074367,0.053860976884978005,-0.09094104587744528,1.463832977402664,-0.7494501896778172,0.14902186735214557,0.4282542060735226,0.8308572620954069,-0.09094104587744528,-0.13977468780074367,-0.18889877938207092,-0.09094104587744528,0.38234507015049096,0.053860976884978005,-0.04239342030431858,0.5645328647779381,2.8638632384419833,1.7843606013886042,-0.23831786606746352,-0.28803660939734893,-0.3380597911426015,-0.3380597911426015,1.0893972532895093,9.674117275578304,0.38234507015049096,0.3361888423900969
| 3,367
|
Copii coated er to golgi transport vesicle
| 12
| 29
| 2.465106
| 0.013697
|
O95070,O15027,P05067,Q5VYK3,Q08379,O95487,P53634,Q12907,P01889,P04439,Q13190,Q9Y282
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
423,275,190,41,75,466,328,150,126,424,396,31
|
275,1205,2302,1466,994,423,996,466,126,424,190,1601,1777,1012,328,1498,3128,75,150,396,1388,1807,41,558,972,3168,31,3008,1315
|
0.7870267798407822,0.10157608769830284,-0.28803660939734893,0.005872513874080369,0.19620224214011292,0.5645328647779381,0.19620224214011292,0.5193447980380466,1.381940746478781,0.5645328647779381,1.046822951105993,-0.04239342030431858,-0.09094104587744528,0.19620224214011292,0.6987063152944422,0.005872513874080369,-0.8553842121388305,1.9017911284204507,1.257715066848026,0.6094870655900769,0.053860976884978005,-0.09094104587744528,2.899060884241353,0.4739196680085796,0.24312104666747653,-0.908808220790615,3.2104683932450104,-0.6447419635510961,0.10157608769830284
| 3,367
|
Antigen processing cross presentation
| 7
| 50
| 2.463651
| 0.013753
|
P60900,P28074,P49721,Q12846,Q9UIQ6,P28072,P01889
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
128,35,10,114,19,52,126
|
1319,2436,2437,2567,987,2969,875,1466,2846,126,424,2317,1601,1343,192,2458,2179,2041,1895,1349,1771,647,52,35,2329,2193,2197,1011,354,10,1244,2699,3298,2924,128,283,1249,1504,2609,2065,1792,114,1797,481,1524,2824,2258,19,638,2426
|
0.053860976884978005,-0.3380597911426015,-0.3380597911426015,-0.388392317630512,0.19620224214011292,-0.6447419635510961,0.24312104666747653,0.005872513874080369,-0.5412682933157936,1.381940746478781,0.5645328647779381,-0.28803660939734893,-0.04239342030431858,0.053860976884978005,1.046822951105993,-0.3380597911426015,-0.23831786606746352,-0.18889877938207092,-0.13977468780074367,0.053860976884978005,-0.09094104587744528,0.38234507015049096,2.431534530000306,3.0039248680970876,-0.28803660939734893,-0.23831786606746352,-0.23831786606746352,0.19620224214011292,0.6542105287099975,6.0439644005275905,0.10157608769830284,-0.43903817143719953,-1.516266431277383,-0.5928502525010018,1.381940746478781,0.7870267798407822,0.10157608769830284,0.005872513874080369,-0.388392317630512,-0.18889877938207092,-0.09094104587744528,1.463832977402664,-0.09094104587744528,0.5193447980380466,0.005872513874080369,-0.4899972174116964,-0.23831786606746352,4.4014392320994515,0.4282542060735226,-0.28803660939734893
| 3,367
|
Anion transport
| 22
| 59
| 2.45489
| 0.014093
|
P51798,Q9HC21,Q9C0H2,P11166,Q9UHG3,P80404,Q9NZJ7,P14174,P28288,P45880,O60831,Q8TB61,Q6N075,P30825,Q9Y696,P21796,P12236,Q9H2D1,O75915,P30536,P07602,Q00325
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
475,413,145,388,32,36,315,521,428,56,320,367,363,212,237,100,470,105,226,113,468,478
|
2295,2016,1201,722,320,1095,226,1880,1882,1102,1751,468,2451,890,2849,388,2585,470,521,100,428,113,212,2978,56,475,1917,911,2207,2208,36,478,533,2986,1380,753,1654,1033,755,363,938,1271,367,1693,145,1561,105,3281,1438,413,2741,315,1998,32,2550,867,980,2841,237
|
-0.28803660939734893,-0.18889877938207092,0.10157608769830284,0.3361888423900969,0.6987063152944422,0.14902186735214557,0.9178727874245445,-0.13977468780074367,-0.13977468780074367,0.14902186735214557,-0.09094104587744528,0.5193447980380466,-0.3380597911426015,0.24312104666747653,-0.5412682933157936,0.6094870655900769,-0.388392317630512,0.5193447980380466,0.4739196680085796,1.6254733747117993,0.5645328647779381,1.463832977402664,0.961063282020524,-0.6447419635510961,2.394640025697565,0.5193447980380466,-0.13977468780074367,0.24312104666747653,-0.23831786606746352,-0.23831786606746352,2.969090607110795,0.5193447980380466,0.4739196680085796,-0.6447419635510961,0.053860976884978005,0.3361888423900969,-0.04239342030431858,0.19620224214011292,0.3361888423900969,0.6542105287099975,0.24312104666747653,0.10157608769830284,0.6542105287099975,-0.04239342030431858,1.2993115136492674,0.005872513874080369,1.5450050959353323,-1.3470325431471153,0.053860976884978005,0.6094870655900769,-0.43903817143719953,0.7429774213920438,-0.13977468780074367,3.073237531524794,-0.3380597911426015,0.2897820267826493,0.24312104666747653,-0.4899972174116964,0.9178727874245445
| 3,367
|
Cholesterol binding
| 7
| 14
| 2.442321
| 0.014593
|
Q14108,P21796,P30536,P61916,P45880,O15118,Q9H4L5
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
164,100,113,149,56,125,341
|
125,885,2450,100,1607,113,429,56,149,164,1145,1296,2535,341
|
1.381940746478781,0.24312104666747653,-0.3380597911426015,1.6254733747117993,-0.04239342030431858,1.463832977402664,0.5645328647779381,2.394640025697565,1.257715066848026,1.1739472326847418,0.14902186735214557,0.10157608769830284,-0.3380597911426015,0.6987063152944422
| 3,367
|
Transporter activity
| 26
| 144
| 2.438682
| 0.014741
|
O43772,O60830,Q9C0H2,Q99595,P61916,Q8IXU6,Q8WTV0,O75964,Q96GC9,Q70HW3,Q9NS69,Q9HD20,O43676,P45880,Q9BVC6,O15173,Q9NRK6,Q9P0J0,P30825,P04062,P21796,Q9H2D1,P30536,Q9UDW1,P21281,O15118
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
2,12,145,18,149,22,25,33,174,45,46,51,55,56,65,189,207,220,212,99,100,105,113,118,121,125
|
2842,3338,2295,1460,2016,420,3096,125,189,2969,55,1201,2,722,12,2910,1874,1465,2025,1095,584,33,1097,3290,2027,519,3102,1880,3349,727,1471,99,1597,1102,1334,2168,2450,2451,890,1336,2849,2319,388,2585,470,1000,1226,1889,1605,2588,2322,121,588,100,1110,1347,2777,428,2590,113,212,1615,297,1905,1358,1492,2978,56,3191,2338,909,1012,2864,475,527,1625,1365,1917,911,2208,742,529,3298,532,1249,149,746,478,533,3156,926,2229,1145,1033,755,839,1530,363,2376,938,1271,1397,45,22,1827,768,1952,367,25,953,3163,174,1175,1692,18,1693,2117,500,65,2532,1296,145,2898,2535,105,341,3281,1438,413,51,207,46,220,1998,118,1305,372,867,3007,3289,980,2006,237,1457
|
-0.5412682933157936,-2.2192938988489903,-0.28803660939734893,0.005872513874080369,-0.18889877938207092,0.5645328647779381,-0.8022645150247569,1.381940746478781,1.046822951105993,-0.6447419635510961,2.394640025697565,0.10157608769830284,8.462226464311355,0.3361888423900969,5.531143228715627,-0.5928502525010018,-0.13977468780074367,0.005872513874080369,-0.18889877938207092,0.14902186735214557,0.4282542060735226,3.0386401585275027,0.14902186735214557,-1.4595613570006674,-0.18889877938207092,0.4739196680085796,-0.8022645150247569,-0.13977468780074367,-2.8994916636965624,0.3361888423900969,0.005872513874080369,1.6254733747117993,-0.04239342030431858,0.14902186735214557,0.053860976884978005,-0.23831786606746352,-0.3380597911426015,-0.3380597911426015,0.24312104666747653,0.053860976884978005,-0.5412682933157936,-0.28803660939734893,0.6094870655900769,-0.388392317630512,0.5193447980380466,0.19620224214011292,0.10157608769830284,-0.13977468780074367,-0.04239342030431858,-0.388392317630512,-0.28803660939734893,1.422977916752635,0.4282542060735226,1.6254733747117993,0.14902186735214557,0.053860976884978005,-0.4899972174116964,0.5645328647779381,-0.388392317630512,1.463832977402664,0.961063282020524,-0.04239342030431858,0.7429774213920438,-0.13977468780074367,0.053860976884978005,0.005872513874080369,-0.6447419635510961,2.394640025697565,-1.0165649980725264,-0.28803660939734893,0.24312104666747653,0.19620224214011292,-0.5412682933157936,0.5193447980380466,0.4739196680085796,-0.04239342030431858,0.053860976884978005,-0.13977468780074367,0.24312104666747653,-0.23831786606746352,0.3361888423900969,0.4739196680085796,-1.516266431277383,0.4739196680085796,0.10157608769830284,1.257715066848026,0.3361888423900969,0.5193447980380466,0.4739196680085796,-0.908808220790615,0.24312104666747653,-0.23831786606746352,0.14902186735214557,0.19620224214011292,0.3361888423900969,0.2897820267826493,0.005872513874080369,0.6542105287099975,-0.28803660939734893,0.24312104666747653,0.10157608769830284,0.053860976884978005,2.7575257190991964,4.1860297014667704,-0.09094104587744528,0.3361888423900969,-0.13977468780074367,0.6542105287099975,3.6115632124813404,0.24312104666747653,-0.908808220790615,1.1317712009042973,0.14902186735214557,-0.04239342030431858,4.731666431481315,-0.04239342030431858,-0.18889877938207092,0.5193447980380466,2.0943433015075343,-0.3380597911426015,0.10157608769830284,1.2993115136492674,-0.5412682933157936,-0.3380597911426015,1.5450050959353323,0.6987063152944422,-1.3470325431471153,0.053860976884978005,0.6094870655900769,2.5049104893301823,1.004045806677848,2.7575257190991964,0.961063282020524,-0.13977468780074367,1.463832977402664,0.10157608769830284,0.6542105287099975,0.2897820267826493,-0.6447419635510961,-1.403149751562867,0.24312104666747653,-0.13977468780074367,0.9178727874245445,0.053860976884978005
| 3,367
|
Lipid homeostasis
| 11
| 23
| 2.433737
| 0.014944
|
Q9NQC3,P35610,P34913,O15254,Q6IAA8,P61916,O15118,Q5BJF2,Q8WTV0,O15260,Q9UHB6
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
129,429,179,73,266,149,125,24,25,379,507
|
1577,125,73,379,996,2920,2043,179,429,149,2870,2986,2501,24,266,1666,25,2254,559,129,507,2748,2012
|
-0.04239342030431858,1.381940746478781,1.9792784396533925,0.6094870655900769,0.19620224214011292,-0.5928502525010018,-0.18889877938207092,1.0893972532895093,0.5645328647779381,1.257715066848026,-0.5412682933157936,-0.6447419635510961,-0.3380597911426015,3.9345059665079796,0.8308572620954069,-0.04239342030431858,3.6115632124813404,-0.23831786606746352,0.4739196680085796,1.381940746478781,0.5193447980380466,-0.43903817143719953,-0.13977468780074367
| 3,367
|
SLC superfamily of solute carriers
| 14
| 38
| 2.432634
| 0.014989
|
P30825,O43772,Q9HC21,P12236,O95202,Q9H2D1,Q9NZJ7,Q70HW3,Q9BSK2,Q8IXU6,Q00325,P11166,Q8TB61,Q6N075
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
212,2,413,470,519,105,315,45,500,22,478,388,367,363
|
3096,2,722,1095,519,1880,1102,890,388,2585,470,212,2978,1917,911,2208,478,533,1033,755,363,2376,938,1271,45,22,367,1693,500,2898,105,3281,1438,413,315,1998,867,2012
|
-0.8022645150247569,8.462226464311355,0.3361888423900969,0.14902186735214557,0.4739196680085796,-0.13977468780074367,0.14902186735214557,0.24312104666747653,0.6094870655900769,-0.388392317630512,0.5193447980380466,0.961063282020524,-0.6447419635510961,-0.13977468780074367,0.24312104666747653,-0.23831786606746352,0.5193447980380466,0.4739196680085796,0.19620224214011292,0.3361888423900969,0.6542105287099975,-0.28803660939734893,0.24312104666747653,0.10157608769830284,2.7575257190991964,4.1860297014667704,0.6542105287099975,-0.04239342030431858,0.5193447980380466,-0.5412682933157936,1.5450050959353323,-1.3470325431471153,0.053860976884978005,0.6094870655900769,0.7429774213920438,-0.13977468780074367,0.2897820267826493,-0.13977468780074367
| 3,367
|
Glycerophospholipid metabolic process
| 13
| 59
| 2.426814
| 0.015232
|
Q96Q15,Q96N66,Q8NCC3,Q9H490,Q9NPH0,Q9UG56,Q96S52,Q86TV6,Q92604,Q8N9F7,Q8WTV0,P42356,P35790
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
64,337,4,313,38,316,175,335,172,307,25,239,213
|
1317,873,807,1199,2673,3055,887,385,2311,1470,818,1890,3225,1613,213,1233,239,1909,1911,1624,1926,665,835,606,674,335,1945,3258,366,307,4,2246,3136,25,2249,1048,172,1548,623,1413,337,64,175,2889,555,1838,963,2402,1844,2405,1296,2123,313,38,2543,793,316,2283,1312
|
0.053860976884978005,0.24312104666747653,0.2897820267826493,0.10157608769830284,-0.43903817143719953,-0.7494501896778172,0.24312104666747653,0.6094870655900769,-0.28803660939734893,0.005872513874080369,0.2897820267826493,-0.13977468780074367,-1.1255266262233685,-0.04239342030431858,0.961063282020524,0.10157608769830284,0.8744716799879915,-0.13977468780074367,-0.13977468780074367,-0.04239342030431858,-0.13977468780074367,0.38234507015049096,0.2897820267826493,0.4282542060735226,0.38234507015049096,0.6987063152944422,-0.13977468780074367,-1.2356850843636273,0.6542105287099975,0.7429774213920438,7.298411945543759,-0.23831786606746352,-0.8553842121388305,3.6115632124813404,-0.23831786606746352,0.19620224214011292,1.1317712009042973,0.005872513874080369,0.4282542060735226,0.053860976884978005,0.6987063152944422,2.132393733047149,1.1317712009042973,-0.5412682933157936,0.4739196680085796,-0.09094104587744528,0.24312104666747653,-0.28803660939734893,-0.09094104587744528,-0.28803660939734893,0.10157608769830284,-0.18889877938207092,0.7429774213920438,2.969090607110795,-0.3380597911426015,0.3361888423900969,0.7429774213920438,-0.23831786606746352,0.10157608769830284
| 3,367
|
Abnormal epiphyseal ossification
| 6
| 17
| 2.363779
| 0.01809
|
O43933,Q15125,Q2M1P5,Q9UBM7,Q14739,Q96L58
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
98,74,205,54,151,215
|
2669,98,1739,882,1222,1358,530,151,2711,74,1938,205,958,1172,215,54,316
|
-0.43903817143719953,1.6254733747117993,-0.09094104587744528,0.24312104666747653,0.10157608769830284,0.053860976884978005,0.4739196680085796,1.257715066848026,-0.43903817143719953,1.9792784396533925,-0.13977468780074367,1.004045806677848,0.24312104666747653,0.14902186735214557,0.961063282020524,2.431534530000306,0.7429774213920438
| 3,367
|
Supranuclear gaze palsy
| 10
| 20
| 2.362013
| 0.018176
|
Q96RL7,Q969N2,P04062,Q96RR1,Q99720,Q9NZJ7,P07602,P35637,P61916,O15118
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
216,623,99,553,43,315,468,326,149,125
|
2438,986,125,99,468,1756,1901,326,2346,149,603,1648,1650,623,216,553,43,315,1451,797
|
-0.3380597911426015,0.19620224214011292,1.381940746478781,1.6254733747117993,0.5193447980380466,-0.09094104587744528,-0.13977468780074367,0.6987063152944422,-0.28803660939734893,1.257715066848026,0.4282542060735226,-0.04239342030431858,-0.04239342030431858,0.4282542060735226,0.961063282020524,0.4739196680085796,2.8638632384419833,0.7429774213920438,0.053860976884978005,0.3361888423900969
| 3,367
|
Sterol homeostasis
| 7
| 11
| 2.358284
| 0.01836
|
P35610,Q6IAA8,P61916,Q5BJF2,Q8WTV0,P34913,O15118
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
429,266,149,24,25,179,125
|
125,996,179,429,149,24,266,25,2254,507,2748
|
1.381940746478781,0.19620224214011292,1.0893972532895093,0.5645328647779381,1.257715066848026,3.9345059665079796,0.8308572620954069,3.6115632124813404,-0.23831786606746352,0.5193447980380466,-0.43903817143719953
| 3,367
|
Sterol binding
| 7
| 17
| 2.352571
| 0.018644
|
Q14108,P21796,P30536,P61916,P45880,O15118,Q9H4L5
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
164,100,113,149,56,125,341
|
125,885,2450,100,1110,1607,113,429,56,149,164,1145,1175,2532,1296,2535,341
|
1.381940746478781,0.24312104666747653,-0.3380597911426015,1.6254733747117993,0.14902186735214557,-0.04239342030431858,1.463832977402664,0.5645328647779381,2.394640025697565,1.257715066848026,1.1739472326847418,0.14902186735214557,0.14902186735214557,-0.3380597911426015,0.10157608769830284,-0.3380597911426015,0.6987063152944422
| 3,367
|
Defective cftr causes cystic fibrosis
| 7
| 39
| 2.337669
| 0.019404
|
P60900,P28074,P20618,P49721,Q9BUN8,P28072,P61289
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
128,35,192,10,80,52,283
|
1319,2436,2437,2567,875,2846,885,1343,192,2458,2179,2041,1895,1771,647,52,35,2193,2197,1011,354,10,1244,2699,2346,128,283,1504,2609,2065,1792,1797,481,1524,2824,2258,80,638,2426
|
0.053860976884978005,-0.3380597911426015,-0.3380597911426015,-0.388392317630512,0.24312104666747653,-0.5412682933157936,0.24312104666747653,0.053860976884978005,1.046822951105993,-0.3380597911426015,-0.23831786606746352,-0.18889877938207092,-0.13977468780074367,-0.09094104587744528,0.38234507015049096,2.431534530000306,3.0039248680970876,-0.23831786606746352,-0.23831786606746352,0.19620224214011292,0.6542105287099975,6.0439644005275905,0.10157608769830284,-0.43903817143719953,-0.28803660939734893,1.381940746478781,0.7870267798407822,0.005872513874080369,-0.388392317630512,-0.18889877938207092,-0.09094104587744528,-0.09094104587744528,0.5193447980380466,0.005872513874080369,-0.4899972174116964,-0.23831786606746352,1.8628092769514064,0.4282542060735226,-0.28803660939734893
| 3,367
|
Abc transporter disorders
| 7
| 39
| 2.337669
| 0.019404
|
P60900,P28074,P20618,P49721,Q9BUN8,P28072,P61289
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
128,35,192,10,80,52,283
|
1319,2436,2437,2567,875,2846,885,1343,192,2458,2179,2041,1895,1771,647,52,35,2193,2197,1011,354,10,1244,2699,2346,128,283,1504,2609,2065,1792,1797,481,1524,2824,2258,80,638,2426
|
0.053860976884978005,-0.3380597911426015,-0.3380597911426015,-0.388392317630512,0.24312104666747653,-0.5412682933157936,0.24312104666747653,0.053860976884978005,1.046822951105993,-0.3380597911426015,-0.23831786606746352,-0.18889877938207092,-0.13977468780074367,-0.09094104587744528,0.38234507015049096,2.431534530000306,3.0039248680970876,-0.23831786606746352,-0.23831786606746352,0.19620224214011292,0.6542105287099975,6.0439644005275905,0.10157608769830284,-0.43903817143719953,-0.28803660939734893,1.381940746478781,0.7870267798407822,0.005872513874080369,-0.388392317630512,-0.18889877938207092,-0.09094104587744528,-0.09094104587744528,0.5193447980380466,0.005872513874080369,-0.4899972174116964,-0.23831786606746352,1.8628092769514064,0.4282542060735226,-0.28803660939734893
| 3,367
|
Amide binding
| 27
| 104
| 2.329853
| 0.019814
|
Q02252,Q9UIQ6,O60684,Q8WTV0,Q9BYT8,P55786,Q9H2P0,Q9NZJ7,Q9NZ08,Q9NXR7,P45880,P55899,P00374,P04439,P42892,P35610,Q9UM22,Q9Y680,Q92947,Q13427,Q14978,Q99735,O14773,P21796,P49748,P07602,P01889
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
136,19,382,25,154,159,447,315,47,452,56,180,59,424,63,429,68,69,494,88,332,217,319,100,230,468,126
|
2435,577,1459,1197,806,2439,319,2969,2154,2765,382,2304,1097,59,126,424,3021,1749,468,1753,1219,1220,1601,2320,728,2854,100,1607,1608,3176,1770,1349,2857,2591,2184,2977,429,900,1356,1233,2978,63,906,56,2339,1239,230,1013,1241,2473,1364,3252,1365,159,180,2059,1249,2349,1511,1023,746,832,136,1791,3228,3268,3218,1642,1257,88,1519,1138,2081,332,3232,2632,2106,25,494,775,777,1833,1415,2823,554,1838,217,2267,154,447,3117,2128,2412,452,47,315,1306,2746,19,68,2002,1080,3011,69
|
-0.3380597911426015,0.4282542060735226,0.005872513874080369,0.10157608769830284,0.2897820267826493,-0.3380597911426015,0.6987063152944422,-0.6447419635510961,-0.23831786606746352,-0.4899972174116964,0.6094870655900769,-0.28803660939734893,0.14902186735214557,2.283114015588119,1.381940746478781,0.5645328647779381,-0.6969423099361801,-0.09094104587744528,0.5193447980380466,-0.09094104587744528,0.10157608769830284,0.10157608769830284,-0.04239342030431858,-0.28803660939734893,0.3361888423900969,-0.5412682933157936,1.6254733747117993,-0.04239342030431858,-0.04239342030431858,-0.9625354940644615,-0.09094104587744528,0.053860976884978005,-0.5412682933157936,-0.388392317630512,-0.23831786606746352,-0.6447419635510961,0.5645328647779381,0.24312104666747653,0.053860976884978005,0.10157608769830284,-0.6447419635510961,2.132393733047149,0.24312104666747653,2.394640025697565,-0.28803660939734893,0.10157608769830284,0.9178727874245445,0.19620224214011292,0.10157608769830284,-0.3380597911426015,0.053860976884978005,-1.2356850843636273,0.053860976884978005,1.2159277397438069,1.0893972532895093,-0.18889877938207092,0.10157608769830284,-0.28803660939734893,0.005872513874080369,0.19620224214011292,0.3361888423900969,0.2897820267826493,1.3407193358749927,-0.09094104587744528,-1.1255266262233685,-1.2912106707426125,-1.070895711677453,-0.04239342030431858,0.10157608769830284,1.7052535001830216,0.005872513874080369,0.14902186735214557,-0.18889877938207092,0.6987063152944422,-1.1255266262233685,-0.388392317630512,-0.18889877938207092,3.6115632124813404,0.5193447980380466,0.3361888423900969,0.3361888423900969,-0.09094104587744528,0.053860976884978005,-0.4899972174116964,0.4739196680085796,-0.09094104587744528,0.961063282020524,-0.23831786606746352,1.257715066848026,0.5645328647779381,-0.8022645150247569,-0.18889877938207092,-0.28803660939734893,0.5645328647779381,2.5777445433602932,0.7429774213920438,0.10157608769830284,-0.43903817143719953,4.4014392320994515,2.0561416638490693,-0.13977468780074367,0.19620224214011292,-0.6447419635510961,2.0561416638490693
| 3,367
|
Glycolipid binding
| 6
| 9
| 2.323368
| 0.020159
|
Q9UM22,Q9H490,Q9NZJ7,P50897,P54652,O14773
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
68,313,315,261,329,319
|
319,468,261,329,1631,1548,313,315,68
|
0.6987063152944422,0.5193447980380466,0.8308572620954069,0.6987063152944422,-0.04239342030431858,0.005872513874080369,0.7429774213920438,0.7429774213920438,2.0561416638490693
| 3,367
|
Rac3 gtpase cycle
| 8
| 33
| 2.313678
| 0.020685
|
Q9UQB8,O15173,Q6IAA8,O75962,Q7L576,Q14739,Q9NRY4,P50402
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
0,189,266,352,305,151,156,214
|
189,579,352,1472,1751,2582,1116,736,3251,1777,214,1014,1125,1926,358,2617,1796,1142,151,755,3242,1268,266,305,2395,1976,1697,1561,156,2277,0,869,2429
|
1.046822951105993,0.4282542060735226,0.6542105287099975,0.005872513874080369,-0.09094104587744528,-0.388392317630512,0.14902186735214557,0.3361888423900969,-1.2356850843636273,-0.09094104587744528,0.961063282020524,0.19620224214011292,0.14902186735214557,-0.13977468780074367,0.6542105287099975,-0.388392317630512,-0.09094104587744528,0.14902186735214557,1.257715066848026,0.3361888423900969,-1.1804567452748522,0.10157608769830284,0.8308572620954069,0.7429774213920438,-0.28803660939734893,-0.13977468780074367,-0.04239342030431858,0.005872513874080369,1.257715066848026,-0.23831786606746352,9.674117275578304,0.2897820267826493,-0.28803660939734893
| 3,367
|
Snare complex
| 8
| 13
| 2.311876
| 0.020785
|
Q86Y82,O15400,O43752,Q9UNK0,O95721,Q12846,Q9P2W9,Q13190
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
196,276,516,177,228,114,505,396
|
276,579,516,1466,228,1499,114,925,396,196,2260,505,177
|
0.7870267798407822,0.4282542060735226,0.4739196680085796,0.005872513874080369,0.9178727874245445,0.005872513874080369,1.463832977402664,0.24312104666747653,0.6094870655900769,1.046822951105993,-0.23831786606746352,0.5193447980380466,1.1317712009042973
| 3,367
|
Regulation of hmox1 expression and activity
| 10
| 47
| 2.310287
| 0.020872
|
P60900,P28074,Q13309,Q8TCT9,P20618,P49721,P49720,P28072,P61289,P09601
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
128,35,232,235,192,10,354,52,283,60
|
1319,2436,2437,2567,2968,875,2846,60,1343,1003,192,2458,2179,2041,1895,1771,647,52,35,2193,2197,1011,354,10,1244,2699,128,283,1504,2609,2065,394,1636,2352,1792,1797,232,3241,2492,1258,481,1524,235,2824,2258,638,2426
|
0.053860976884978005,-0.3380597911426015,-0.3380597911426015,-0.388392317630512,-0.6447419635510961,0.24312104666747653,-0.5412682933157936,2.283114015588119,0.053860976884978005,0.19620224214011292,1.046822951105993,-0.3380597911426015,-0.23831786606746352,-0.18889877938207092,-0.13977468780074367,-0.09094104587744528,0.38234507015049096,2.431534530000306,3.0039248680970876,-0.23831786606746352,-0.23831786606746352,0.19620224214011292,0.6542105287099975,6.0439644005275905,0.10157608769830284,-0.43903817143719953,1.381940746478781,0.7870267798407822,0.005872513874080369,-0.388392317630512,-0.18889877938207092,0.6094870655900769,-0.04239342030431858,-0.28803660939734893,-0.09094104587744528,-0.09094104587744528,0.9178727874245445,-1.1804567452748522,-0.3380597911426015,0.10157608769830284,0.5193447980380466,0.005872513874080369,0.9178727874245445,-0.4899972174116964,-0.23831786606746352,0.4282542060735226,-0.28803660939734893
| 3,367
|
Switching of origins to a post replicative state
| 14
| 58
| 2.309868
| 0.020895
|
P60900,P28074,P30260,Q13309,P20618,P49721,Q99741,Q9UJX6,P49720,Q96DE5,P28072,Q9UBD5,P61289,P63208
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
128,35,391,232,192,10,498,317,354,96,52,221,283,394
|
1319,2436,2437,2567,875,1586,2846,1343,192,1229,2325,2458,2179,2041,1895,1771,647,52,35,391,2190,1618,2046,2193,2197,1011,354,10,1496,1244,2699,128,283,1504,2609,2065,394,1792,833,1797,232,3241,1934,481,1524,1810,96,2824,2258,498,221,868,1308,1999,2661,317,638,2426
|
0.053860976884978005,-0.3380597911426015,-0.3380597911426015,-0.388392317630512,0.24312104666747653,-0.04239342030431858,-0.5412682933157936,0.053860976884978005,1.046822951105993,0.10157608769830284,-0.28803660939734893,-0.3380597911426015,-0.23831786606746352,-0.18889877938207092,-0.13977468780074367,-0.09094104587744528,0.38234507015049096,2.431534530000306,3.0039248680970876,0.6094870655900769,-0.23831786606746352,-0.04239342030431858,-0.18889877938207092,-0.23831786606746352,-0.23831786606746352,0.19620224214011292,0.6542105287099975,6.0439644005275905,0.005872513874080369,0.10157608769830284,-0.43903817143719953,1.381940746478781,0.7870267798407822,0.005872513874080369,-0.388392317630512,-0.18889877938207092,0.6094870655900769,-0.09094104587744528,0.2897820267826493,-0.09094104587744528,0.9178727874245445,-1.1804567452748522,-0.13977468780074367,0.5193447980380466,0.005872513874080369,-0.09094104587744528,1.6654484983059537,-0.4899972174116964,-0.23831786606746352,0.5193447980380466,0.961063282020524,0.2897820267826493,0.10157608769830284,-0.13977468780074367,-0.388392317630512,0.7429774213920438,0.4282542060735226,-0.28803660939734893
| 3,367
|
Snap receptor activity
| 8
| 11
| 2.299442
| 0.02148
|
Q86Y82,O15400,O43752,Q9UNK0,O95721,Q12846,Q9P2W9,Q13190
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
196,276,516,177,228,114,505,396
|
276,579,516,1466,228,114,925,396,196,505,177
|
0.7870267798407822,0.4282542060735226,0.4739196680085796,0.005872513874080369,0.9178727874245445,1.463832977402664,0.24312104666747653,0.6094870655900769,1.046822951105993,0.5193447980380466,1.1317712009042973
| 3,367
|
Snare interactions in vesicular transport
| 8
| 11
| 2.299442
| 0.02148
|
Q86Y82,O15400,O43752,Q9UNK0,O95721,Q12846,Q9P2W9,Q13190
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
196,276,516,177,228,114,505,396
|
276,579,516,1466,228,114,925,396,196,505,177
|
0.7870267798407822,0.4282542060735226,0.4739196680085796,0.005872513874080369,0.9178727874245445,1.463832977402664,0.24312104666747653,0.6094870655900769,1.046822951105993,0.5193447980380466,1.1317712009042973
| 3,367
|
Regulation of lipid metabolic process
| 14
| 53
| 2.295897
| 0.021682
|
P49748,Q6IAA8,Q9NZJ7,Q92604,P30536,Q2T9J0,Q96G23,P61916,Q9UBM7,O75844,Q8WTV0,P34913,O95822,P83111
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
230,266,315,172,113,49,20,149,54,87,25,179,280,243
|
2439,2571,3286,463,87,1877,885,887,280,1882,1597,468,469,1340,818,113,589,179,590,826,230,828,1124,1125,149,243,2793,2352,2986,3195,835,606,837,754,932,49,1534,266,2246,3136,25,172,2254,20,337,555,1838,315,54,2424,2549,2283,3211
|
-0.3380597911426015,-0.388392317630512,-1.403149751562867,0.5193447980380466,1.7052535001830216,-0.13977468780074367,0.24312104666747653,0.24312104666747653,0.7870267798407822,-0.13977468780074367,-0.04239342030431858,0.5193447980380466,0.5193447980380466,0.053860976884978005,0.2897820267826493,1.463832977402664,0.4282542060735226,1.0893972532895093,0.4282542060735226,0.2897820267826493,0.9178727874245445,0.2897820267826493,0.14902186735214557,0.14902186735214557,1.257715066848026,0.8744716799879915,-0.4899972174116964,-0.28803660939734893,-0.6447419635510961,-1.0165649980725264,0.2897820267826493,0.4282542060735226,0.2897820267826493,0.3361888423900969,0.24312104666747653,2.5413946027810876,0.005872513874080369,0.8308572620954069,-0.23831786606746352,-0.8553842121388305,3.6115632124813404,1.1317712009042973,-0.23831786606746352,4.309639278406814,0.6987063152944422,0.4739196680085796,-0.09094104587744528,0.7429774213920438,2.431534530000306,-0.28803660939734893,-0.3380597911426015,-0.23831786606746352,-1.0165649980725264
| 3,367
|
Cell recognition
| 7
| 26
| 2.290455
| 0.021995
|
Q9NQC3,P05067,Q08431,O14967,P45880,Q8WTV0,Q9NRY4
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
129,190,284,211,56,25,156
|
1580,211,720,2165,190,1342,2175,1004,825,2335,56,2781,2470,2201,2202,2350,2218,284,331,1532,2243,25,2522,2261,129,156
|
-0.04239342030431858,0.961063282020524,0.3361888423900969,-0.23831786606746352,1.046822951105993,0.053860976884978005,-0.23831786606746352,0.19620224214011292,0.2897820267826493,-0.28803660939734893,2.394640025697565,-0.4899972174116964,-0.3380597911426015,-0.23831786606746352,-0.23831786606746352,-0.28803660939734893,-0.23831786606746352,0.7870267798407822,0.6987063152944422,0.005872513874080369,-0.23831786606746352,3.6115632124813404,-0.3380597911426015,-0.23831786606746352,1.381940746478781,1.257715066848026
| 3,367
|
Subsets and Splits
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