term
stringlengths
2
121
overlap
int64
6
281
setsize
int64
7
499
score
float64
1.96
10.6
pval
float64
0
0.05
edge
stringlengths
41
1.97k
type
stringclasses
5 values
subtype
stringclasses
24 values
subtype_key
stringclasses
24 values
edge_idxs
stringlengths
11
1.17k
ann_idxs
stringlengths
19
2.31k
ann_vals
stringlengths
124
9.94k
sig_size
int64
2.2k
3.73k
Hedgehog on state
8
42
2.287921
0.022142
P60900,P28074,P20618,P49721,Q9Y496,Q2M1P5,P28072,P61289
Processes and pathways
Reactome Pathways
msigdb_reactome
128,35,192,10,318,205,52,283
1319,2436,2437,2567,875,2846,1343,192,2458,2179,2041,1895,1771,647,52,35,2193,2197,1011,653,354,10,1244,2699,128,283,1504,2609,2065,1792,1797,2492,481,1524,205,2879,1174,2824,2258,638,2426,318
0.053860976884978005,-0.3380597911426015,-0.3380597911426015,-0.388392317630512,0.24312104666747653,-0.5412682933157936,0.053860976884978005,1.046822951105993,-0.3380597911426015,-0.23831786606746352,-0.18889877938207092,-0.13977468780074367,-0.09094104587744528,0.38234507015049096,2.431534530000306,3.0039248680970876,-0.23831786606746352,-0.23831786606746352,0.19620224214011292,0.38234507015049096,0.6542105287099975,6.0439644005275905,0.10157608769830284,-0.43903817143719953,1.381940746478781,0.7870267798407822,0.005872513874080369,-0.388392317630512,-0.18889877938207092,-0.09094104587744528,-0.09094104587744528,-0.3380597911426015,0.5193447980380466,0.005872513874080369,1.004045806677848,-0.5412682933157936,0.14902186735214557,-0.4899972174116964,-0.23831786606746352,0.4282542060735226,-0.28803660939734893,0.7429774213920438
3,367
Glycerolipid metabolic process
13
65
2.287344
0.022176
Q96Q15,Q96N66,Q8NCC3,Q9H490,Q9NPH0,Q9UG56,Q96S52,Q86TV6,Q92604,Q8N9F7,Q8WTV0,P42356,P35790
Processes and pathways
GO Biological process
msigdb_gobp
64,337,4,313,38,316,175,335,172,307,25,239,213
1317,873,807,1199,2673,3055,887,385,2311,1470,818,1890,3225,1613,2188,213,1233,239,1909,1911,828,1624,1926,2984,665,835,606,2086,1812,674,335,1945,3258,366,307,4,2246,3136,25,2249,1048,172,1548,623,1413,2254,337,64,175,2889,555,1838,963,2402,1844,2405,1296,2123,313,38,2543,793,316,2283,1312
0.053860976884978005,0.24312104666747653,0.2897820267826493,0.10157608769830284,-0.43903817143719953,-0.7494501896778172,0.24312104666747653,0.6094870655900769,-0.28803660939734893,0.005872513874080369,0.2897820267826493,-0.13977468780074367,-1.1255266262233685,-0.04239342030431858,-0.23831786606746352,0.961063282020524,0.10157608769830284,0.8744716799879915,-0.13977468780074367,-0.13977468780074367,0.2897820267826493,-0.04239342030431858,-0.13977468780074367,-0.6447419635510961,0.38234507015049096,0.2897820267826493,0.4282542060735226,-0.18889877938207092,-0.09094104587744528,0.38234507015049096,0.6987063152944422,-0.13977468780074367,-1.2356850843636273,0.6542105287099975,0.7429774213920438,7.298411945543759,-0.23831786606746352,-0.8553842121388305,3.6115632124813404,-0.23831786606746352,0.19620224214011292,1.1317712009042973,0.005872513874080369,0.4282542060735226,0.053860976884978005,-0.23831786606746352,0.6987063152944422,2.132393733047149,1.1317712009042973,-0.5412682933157936,0.4739196680085796,-0.09094104587744528,0.24312104666747653,-0.28803660939734893,-0.09094104587744528,-0.28803660939734893,0.10157608769830284,-0.18889877938207092,0.7429774213920438,2.969090607110795,-0.3380597911426015,0.3361888423900969,0.7429774213920438,-0.23831786606746352,0.10157608769830284
3,367
Lipid localization
25
76
2.285912
0.022259
O43772,Q6IAA8,P61916,O95674,Q8WTV0,O15260,P11166,Q14108,Q99720,Q96GC9,Q9NZJ7,P28288,P07814,Q9BUR5,Q86Y82,Q9H4L5,P35610,Q9BQE5,P23786,Q9H6V9,Q9UHB6,P35790,P04062,P30536,O15118
Processes and pathways
GO Biological process
msigdb_gobp
2,266,149,385,25,379,388,164,43,174,315,428,425,198,196,341,429,218,82,219,507,213,99,113,125
1868,2439,3096,125,379,2,722,1091,2773,996,887,385,1470,2449,99,1882,2168,468,3327,425,2451,388,521,1889,1110,1607,82,428,1900,113,589,2188,429,213,909,828,149,746,2068,2352,2984,3268,2986,164,2621,1145,1534,266,1271,196,3184,3245,25,2254,174,1175,43,218,1697,198,2532,1296,2270,2535,341,219,3006,315,702,1191,507,705,2283,3342,3289,871
-0.13977468780074367,-0.3380597911426015,-0.8022645150247569,1.381940746478781,0.6094870655900769,8.462226464311355,0.3361888423900969,0.14902186735214557,-0.4899972174116964,0.19620224214011292,0.24312104666747653,0.6094870655900769,0.005872513874080369,-0.3380597911426015,1.6254733747117993,-0.13977468780074367,-0.23831786606746352,0.5193447980380466,-1.9803639244210636,0.5645328647779381,-0.3380597911426015,0.6094870655900769,0.4739196680085796,-0.13977468780074367,0.14902186735214557,-0.04239342030431858,1.7843606013886042,0.5645328647779381,-0.13977468780074367,1.463832977402664,0.4282542060735226,-0.23831786606746352,0.5645328647779381,0.961063282020524,0.24312104666747653,0.2897820267826493,1.257715066848026,0.3361888423900969,-0.18889877938207092,-0.28803660939734893,-0.6447419635510961,-1.2912106707426125,-0.6447419635510961,1.1739472326847418,-0.388392317630512,0.14902186735214557,0.005872513874080369,0.8308572620954069,0.10157608769830284,1.046822951105993,-0.9625354940644615,-1.1804567452748522,3.6115632124813404,-0.23831786606746352,1.1317712009042973,0.14902186735214557,2.8638632384419833,0.961063282020524,-0.04239342030431858,1.046822951105993,-0.3380597911426015,0.10157608769830284,-0.23831786606746352,-0.3380597911426015,0.6987063152944422,0.961063282020524,-0.6447419635510961,0.7429774213920438,0.38234507015049096,0.14902186735214557,0.5193447980380466,0.38234507015049096,-0.23831786606746352,-2.340455914597067,-1.403149751562867,0.2897820267826493
3,367
Phospholipid metabolism
11
52
2.283145
0.022422
Q96N66,Q8NCC3,Q8IV08,Q9NPH0,Q8N2A8,Q9NQZ5,Q9UG56,Q92604,Q8N9F7,P42356,P35790
Processes and pathways
Reactome Pathways
msigdb_reactome
337,4,37,38,101,415,316,172,307,239,213
873,807,1199,2673,2157,385,1470,1003,2321,522,213,1233,239,1359,1911,909,2347,1369,1636,1926,665,2226,835,606,1812,1945,37,3258,101,616,307,1278,4,2246,3136,2249,172,337,2399,2889,555,2117,963,2402,1296,2123,2654,38,415,2543,316,1312
0.24312104666747653,0.2897820267826493,0.10157608769830284,-0.43903817143719953,-0.23831786606746352,0.6094870655900769,0.005872513874080369,0.19620224214011292,-0.28803660939734893,0.4739196680085796,0.961063282020524,0.10157608769830284,0.8744716799879915,0.053860976884978005,-0.13977468780074367,0.24312104666747653,-0.28803660939734893,0.053860976884978005,-0.04239342030431858,-0.13977468780074367,0.38234507015049096,-0.23831786606746352,0.2897820267826493,0.4282542060735226,-0.09094104587744528,-0.13977468780074367,2.969090607110795,-1.2356850843636273,1.6254733747117993,0.4282542060735226,0.7429774213920438,0.10157608769830284,7.298411945543759,-0.23831786606746352,-0.8553842121388305,-0.23831786606746352,1.1317712009042973,0.6987063152944422,-0.28803660939734893,-0.5412682933157936,0.4739196680085796,-0.18889877938207092,0.24312104666747653,-0.28803660939734893,0.10157608769830284,-0.18889877938207092,-0.388392317630512,2.969090607110795,0.6094870655900769,-0.3380597911426015,0.7429774213920438,0.10157608769830284
3,367
Inorganic anion transport
9
20
2.280035
0.022606
P51798,Q9UHG3,Q9Y696,P21796,Q9C0H2,P30536,Q00325,P45880,Q6N075
Processes and pathways
GO Biological process
msigdb_gobp
475,32,237,100,145,113,478,56,363
2295,1201,2451,2849,100,113,56,475,2207,2208,478,533,1033,363,145,1561,1998,32,980,237
-0.28803660939734893,0.10157608769830284,-0.3380597911426015,-0.5412682933157936,1.6254733747117993,1.463832977402664,2.394640025697565,0.5193447980380466,-0.23831786606746352,-0.23831786606746352,0.5193447980380466,0.4739196680085796,0.19620224214011292,0.6542105287099975,1.2993115136492674,0.005872513874080369,-0.13977468780074367,3.073237531524794,0.24312104666747653,0.9178727874245445
3,367
Agitation
6
33
2.264335
0.023554
Q15165,P42858,P04062,P05067,P35637,P42892
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
1,392,99,190,326,63
880,995,727,99,190,1103,1221,1222,2178,429,326,392,63,2336,652,1243,1624,2345,2346,2223,1513,603,1648,1650,2622,1,2090,2379,1399,621,960,2951,1290
0.24312104666747653,0.19620224214011292,0.3361888423900969,1.6254733747117993,1.046822951105993,0.14902186735214557,0.10157608769830284,0.10157608769830284,-0.23831786606746352,0.5645328647779381,0.6987063152944422,0.6094870655900769,2.132393733047149,-0.28803660939734893,0.38234507015049096,0.10157608769830284,-0.04239342030431858,-0.28803660939734893,-0.28803660939734893,-0.23831786606746352,0.005872513874080369,0.4282542060735226,-0.04239342030431858,-0.04239342030431858,-0.388392317630512,9.185425981910969,-0.18889877938207092,-0.28803660939734893,0.053860976884978005,0.4282542060735226,0.24312104666747653,-0.5928502525010018,0.10157608769830284
3,367
Cdt1 association with the cdc6 orc origin complex
9
39
2.255413
0.024107
P60900,P28074,P20618,P49721,Q99741,P49720,P28072,Q9UBD5,P61289
Processes and pathways
Reactome Pathways
msigdb_reactome
128,35,192,10,498,354,52,221,283
1319,2436,2437,2567,875,1586,2846,1343,192,2458,2179,2041,1895,1771,647,52,35,2193,2197,1011,354,10,1244,2699,128,283,1504,2609,2065,1792,1797,481,1524,2824,2258,498,221,638,2426
0.053860976884978005,-0.3380597911426015,-0.3380597911426015,-0.388392317630512,0.24312104666747653,-0.04239342030431858,-0.5412682933157936,0.053860976884978005,1.046822951105993,-0.3380597911426015,-0.23831786606746352,-0.18889877938207092,-0.13977468780074367,-0.09094104587744528,0.38234507015049096,2.431534530000306,3.0039248680970876,-0.23831786606746352,-0.23831786606746352,0.19620224214011292,0.6542105287099975,6.0439644005275905,0.10157608769830284,-0.43903817143719953,1.381940746478781,0.7870267798407822,0.005872513874080369,-0.388392317630512,-0.18889877938207092,-0.09094104587744528,-0.09094104587744528,0.5193447980380466,0.005872513874080369,-0.4899972174116964,-0.23831786606746352,0.5193447980380466,0.961063282020524,0.4282542060735226,-0.28803660939734893
3,367
Azurophil granule membrane
9
22
2.247859
0.024585
P42785,P27105,Q6IAA8,Q9NZJ7,O95721,P07602,P51148,O15260,P13473
Localization
GO Cellular component
msigdb_gocc
3,104,266,315,228,468,298,379,389
458,379,2157,880,228,468,2318,3025,389,104,1620,3,298,1377,266,2246,683,956,2117,2898,315,702
0.5193447980380466,0.6094870655900769,-0.23831786606746352,0.24312104666747653,0.9178727874245445,0.5193447980380466,-0.28803660939734893,-0.6969423099361801,0.6094870655900769,1.5450050959353323,-0.04239342030431858,7.767211111294991,0.7429774213920438,0.053860976884978005,0.8308572620954069,-0.23831786606746352,0.38234507015049096,0.24312104666747653,-0.18889877938207092,-0.5412682933157936,0.7429774213920438,0.38234507015049096
3,367
Proteasome
6
35
2.243189
0.024885
P60900,P28074,P20618,P49721,P28072,P61289
Processes and pathways
KEGG Pathways
msigdb_kegg
128,35,192,10,52,283
1319,2436,2437,2567,875,1343,192,2458,2179,2041,1895,1771,647,52,35,2193,2197,1011,354,10,1244,2699,128,283,1504,2609,2065,1792,1797,481,1524,2824,2258,638,2426
0.053860976884978005,-0.3380597911426015,-0.3380597911426015,-0.388392317630512,0.24312104666747653,0.053860976884978005,1.046822951105993,-0.3380597911426015,-0.23831786606746352,-0.18889877938207092,-0.13977468780074367,-0.09094104587744528,0.38234507015049096,2.431534530000306,3.0039248680970876,-0.23831786606746352,-0.23831786606746352,0.19620224214011292,0.6542105287099975,6.0439644005275905,0.10157608769830284,-0.43903817143719953,1.381940746478781,0.7870267798407822,0.005872513874080369,-0.388392317630512,-0.18889877938207092,-0.09094104587744528,-0.09094104587744528,0.5193447980380466,0.005872513874080369,-0.4899972174116964,-0.23831786606746352,0.4282542060735226,-0.28803660939734893
3,367
Hedgehog ligand biogenesis
7
38
2.240855
0.025035
P60900,P28074,P20618,P49721,P07237,P28072,P61289
Processes and pathways
Reactome Pathways
msigdb_reactome
128,35,192,10,323,52,283
1319,2436,2437,2567,875,2846,323,1343,192,2458,2179,2041,1895,1771,647,52,35,2193,2197,1011,354,10,1244,2699,2346,128,283,1504,2609,2065,1792,1797,481,1524,2824,2258,638,2426
0.053860976884978005,-0.3380597911426015,-0.3380597911426015,-0.388392317630512,0.24312104666747653,-0.5412682933157936,0.6987063152944422,0.053860976884978005,1.046822951105993,-0.3380597911426015,-0.23831786606746352,-0.18889877938207092,-0.13977468780074367,-0.09094104587744528,0.38234507015049096,2.431534530000306,3.0039248680970876,-0.23831786606746352,-0.23831786606746352,0.19620224214011292,0.6542105287099975,6.0439644005275905,0.10157608769830284,-0.43903817143719953,-0.28803660939734893,1.381940746478781,0.7870267798407822,0.005872513874080369,-0.388392317630512,-0.18889877938207092,-0.09094104587744528,-0.09094104587744528,0.5193447980380466,0.005872513874080369,-0.4899972174116964,-0.23831786606746352,0.4282542060735226,-0.28803660939734893
3,367
Intrinsic component of mitochondrial inner membrane
12
28
2.237822
0.025233
Q9NX63,Q9HC21,Q9UG56,Q6UXV4,O60830,O14925,Q99595,Q00325,Q13505,Q5XKP0,Q9Y2R0,Q9BUR5
Localization
GO Cellular component
msigdb_gocc
274,413,316,364,12,420,18,478,26,194,157,198
420,3351,12,3100,884,1880,2595,478,26,483,1809,2370,1812,194,364,1952,18,198,630,1438,1439,413,1993,274,316,157,3012,801
0.5645328647779381,-2.962986316850552,5.531143228715627,-0.8022645150247569,0.24312104666747653,-0.13977468780074367,-0.388392317630512,0.5193447980380466,3.578720683939666,0.5193447980380466,-0.09094104587744528,-0.28803660939734893,-0.09094104587744528,1.046822951105993,0.6542105287099975,-0.13977468780074367,4.731666431481315,1.046822951105993,0.4282542060735226,0.053860976884978005,0.053860976884978005,0.6094870655900769,-0.13977468780074367,0.8308572620954069,0.7429774213920438,1.257715066848026,-0.6447419635510961,0.3361888423900969
3,367
Deubiquitination
19
100
2.233339
0.025527
P60900,P49721,Q9NWV8,Q9UPU5,Q15018,O94966,Q70CQ2,P61289,P28074,Q9NXR7,P28072,P45880,P20618,Q13309,Q99496,P21796,P49720,Q96K76,Q8TAF3
Processes and pathways
Reactome Pathways
msigdb_reactome
128,10,417,16,17,383,287,283,35,452,52,56,192,232,369,100,354,254,251
1319,2436,2437,2567,2440,1088,875,3123,2766,2846,1097,383,888,1594,997,1475,728,1343,192,100,2458,2179,2041,1895,1771,647,52,35,2193,590,2197,56,2599,1011,354,10,2203,1244,740,1782,3253,2785,2699,2346,128,283,1504,2609,2065,599,1792,3229,3194,1797,232,749,1380,1258,2496,750,2228,481,1524,17,2713,2802,1154,1535,1155,287,2382,1405,1162,679,251,2394,952,2252,851,254,1690,2824,2258,369,1840,2406,2539,417,452,2959,638,2426,457,16,2836,980,573,2150,3250,2755
0.053860976884978005,-0.3380597911426015,-0.3380597911426015,-0.388392317630512,-0.3380597911426015,0.14902186735214557,0.24312104666747653,-0.8553842121388305,-0.4899972174116964,-0.5412682933157936,0.14902186735214557,0.6094870655900769,0.24312104666747653,-0.04239342030431858,0.19620224214011292,0.005872513874080369,0.3361888423900969,0.053860976884978005,1.046822951105993,1.6254733747117993,-0.3380597911426015,-0.23831786606746352,-0.18889877938207092,-0.13977468780074367,-0.09094104587744528,0.38234507015049096,2.431534530000306,3.0039248680970876,-0.23831786606746352,0.4282542060735226,-0.23831786606746352,2.394640025697565,-0.388392317630512,0.19620224214011292,0.6542105287099975,6.0439644005275905,-0.23831786606746352,0.10157608769830284,0.3361888423900969,-0.09094104587744528,-1.2356850843636273,-0.4899972174116964,-0.43903817143719953,-0.28803660939734893,1.381940746478781,0.7870267798407822,0.005872513874080369,-0.388392317630512,-0.18889877938207092,0.4282542060735226,-0.09094104587744528,-1.1255266262233685,-1.0165649980725264,-0.09094104587744528,0.9178727874245445,0.3361888423900969,0.053860976884978005,0.10157608769830284,-0.3380597911426015,0.3361888423900969,-0.23831786606746352,0.5193447980380466,0.005872513874080369,4.96585588586802,-0.43903817143719953,-0.4899972174116964,0.14902186735214557,0.005872513874080369,0.14902186735214557,0.7870267798407822,-0.28803660939734893,0.053860976884978005,0.14902186735214557,0.38234507015049096,0.8744716799879915,-0.28803660939734893,0.24312104666747653,-0.23831786606746352,0.2897820267826493,0.8744716799879915,-0.04239342030431858,-0.4899972174116964,-0.23831786606746352,0.6542105287099975,-0.09094104587744528,-0.28803660939734893,-0.3380597911426015,0.6094870655900769,0.5645328647779381,-0.5928502525010018,0.4282542060735226,-0.28803660939734893,0.5645328647779381,5.023653846020728,-0.4899972174116964,0.24312104666747653,0.4739196680085796,-0.18889877938207092,-1.1804567452748522,-0.43903817143719953
3,367
SNARE protein
7
8
2.229035
0.025812
Q86Y82,O15400,Q9UNK0,O95721,Q12846,Q9P2W9,Q13190
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
196,276,177,228,114,505,396
276,516,228,114,396,196,505,177
0.7870267798407822,0.4739196680085796,0.9178727874245445,1.463832977402664,0.6094870655900769,1.046822951105993,0.5193447980380466,1.1317712009042973
3,367
SNARE protein
7
8
2.229035
0.025812
Q86Y82,O15400,Q9UNK0,O95721,Q12846,Q9P2W9,Q13190
Functions
Panther Protein class
panther_protein_class
196,276,177,228,114,505,396
276,516,228,114,396,196,505,177
0.7870267798407822,0.4739196680085796,0.9178727874245445,1.463832977402664,0.6094870655900769,1.046822951105993,0.5193447980380466,1.1317712009042973
3,367
Proteasome complex
9
49
2.228854
0.025824
P60900,O43396,P28074,Q9BRP4,P20618,Q5VYK3,P49721,P28072,P61289
Localization
GO Cellular component
msigdb_gocc
128,91,35,370,192,41,10,52,283
1319,2436,2437,2567,875,91,2846,2166,1343,192,2458,2179,2041,1895,1771,647,52,35,2193,2197,1011,354,10,1244,1782,3253,2785,2699,2346,128,283,1504,2609,2065,1928,1792,1797,481,1524,484,2802,41,2634,2824,2258,370,638,2426,2755
0.053860976884978005,-0.3380597911426015,-0.3380597911426015,-0.388392317630512,0.24312104666747653,1.6654484983059537,-0.5412682933157936,-0.23831786606746352,0.053860976884978005,1.046822951105993,-0.3380597911426015,-0.23831786606746352,-0.18889877938207092,-0.13977468780074367,-0.09094104587744528,0.38234507015049096,2.431534530000306,3.0039248680970876,-0.23831786606746352,-0.23831786606746352,0.19620224214011292,0.6542105287099975,6.0439644005275905,0.10157608769830284,-0.09094104587744528,-1.2356850843636273,-0.4899972174116964,-0.43903817143719953,-0.28803660939734893,1.381940746478781,0.7870267798407822,0.005872513874080369,-0.388392317630512,-0.18889877938207092,-0.13977468780074367,-0.09094104587744528,-0.09094104587744528,0.5193447980380466,0.005872513874080369,0.5193447980380466,-0.4899972174116964,2.899060884241353,-0.388392317630512,-0.4899972174116964,-0.23831786606746352,0.6542105287099975,0.4282542060735226,-0.28803660939734893,-0.43903817143719953
3,367
Abc family proteins mediated transport
7
47
2.22668
0.025969
P60900,P28074,P20618,Q9NRK6,P49721,Q9BUN8,P28072
Processes and pathways
Reactome Pathways
msigdb_reactome
128,35,192,207,10,80,52
1319,2436,2437,2567,875,2910,2846,885,2031,2451,1343,2040,192,2458,2179,2041,1895,1771,647,52,35,428,2193,2197,1011,354,10,1244,2699,2346,530,128,283,1504,2609,2065,1792,1797,481,1524,1279,2824,2258,80,207,638,2426
0.053860976884978005,-0.3380597911426015,-0.3380597911426015,-0.388392317630512,0.24312104666747653,-0.5928502525010018,-0.5412682933157936,0.24312104666747653,-0.18889877938207092,-0.3380597911426015,0.053860976884978005,-0.18889877938207092,1.046822951105993,-0.3380597911426015,-0.23831786606746352,-0.18889877938207092,-0.13977468780074367,-0.09094104587744528,0.38234507015049096,2.431534530000306,3.0039248680970876,0.5645328647779381,-0.23831786606746352,-0.23831786606746352,0.19620224214011292,0.6542105287099975,6.0439644005275905,0.10157608769830284,-0.43903817143719953,-0.28803660939734893,0.4739196680085796,1.381940746478781,0.7870267798407822,0.005872513874080369,-0.388392317630512,-0.18889877938207092,-0.09094104587744528,-0.09094104587744528,0.5193447980380466,0.005872513874080369,0.10157608769830284,-0.4899972174116964,-0.23831786606746352,1.8628092769514064,1.004045806677848,0.4282542060735226,-0.28803660939734893
3,367
Dna replication
24
88
2.22561
0.02604
P60900,P49721,Q9NRF9,O60684,P61289,P63208,P28074,P16104,P30260,Q9BRX5,P35250,Q9UJX6,P62805,P35251,P28072,P20618,Q99741,Q9UBD5,Q96DE5,Q9UL46,Q9Y248,Q13309,P49720,Q14997
Processes and pathways
Reactome Pathways
msigdb_reactome
128,10,565,382,283,394,35,158,391,444,524,317,171,296,52,192,498,221,96,638,509,232,354,481
1319,2436,2437,2567,875,1586,382,2846,1755,1479,2174,158,1343,3027,192,1229,2325,2458,2179,2041,1895,1612,1771,647,52,35,2043,391,2190,1618,2046,2859,2332,524,296,2193,2596,591,2597,2978,2197,1011,1240,1495,354,10,1496,1244,3252,2699,1247,128,283,1504,2609,2065,171,394,1792,1516,833,1797,232,3241,1934,2933,2081,481,1524,1810,96,2824,2258,498,2264,444,2742,565,221,868,1308,1999,2661,317,638,2426,509,2964
0.053860976884978005,-0.3380597911426015,-0.3380597911426015,-0.388392317630512,0.24312104666747653,-0.04239342030431858,0.6094870655900769,-0.5412682933157936,-0.09094104587744528,0.005872513874080369,-0.23831786606746352,1.2159277397438069,0.053860976884978005,-0.6969423099361801,1.046822951105993,0.10157608769830284,-0.28803660939734893,-0.3380597911426015,-0.23831786606746352,-0.18889877938207092,-0.13977468780074367,-0.04239342030431858,-0.09094104587744528,0.38234507015049096,2.431534530000306,3.0039248680970876,-0.18889877938207092,0.6094870655900769,-0.23831786606746352,-0.04239342030431858,-0.18889877938207092,-0.5412682933157936,-0.28803660939734893,0.4739196680085796,0.7429774213920438,-0.23831786606746352,-0.388392317630512,0.4282542060735226,-0.388392317630512,-0.6447419635510961,-0.23831786606746352,0.19620224214011292,0.10157608769830284,0.005872513874080369,0.6542105287099975,6.0439644005275905,0.005872513874080369,0.10157608769830284,-1.2356850843636273,-0.43903817143719953,0.10157608769830284,1.381940746478781,0.7870267798407822,0.005872513874080369,-0.388392317630512,-0.18889877938207092,1.1317712009042973,0.6094870655900769,-0.09094104587744528,0.005872513874080369,0.2897820267826493,-0.09094104587744528,0.9178727874245445,-1.1804567452748522,-0.13977468780074367,-0.5928502525010018,-0.18889877938207092,0.5193447980380466,0.005872513874080369,-0.09094104587744528,1.6654484983059537,-0.4899972174116964,-0.23831786606746352,0.5193447980380466,-0.23831786606746352,0.5645328647779381,-0.43903817143719953,0.4739196680085796,0.961063282020524,0.2897820267826493,0.10157608769830284,-0.13977468780074367,-0.388392317630512,0.7429774213920438,0.4282542060735226,-0.28803660939734893,0.5193447980380466,-0.5928502525010018
3,367
Endopeptidase complex
11
56
2.213832
0.02684
P60900,O43396,P28074,Q9BRP4,Q9H490,P20618,Q5VYK3,P49721,Q96S52,P28072,P61289
Localization
GO Cellular component
msigdb_gocc
128,91,35,370,313,192,41,10,175,52,283
1319,2436,2437,2567,875,91,2846,2848,2166,818,1343,192,2458,2179,2041,1895,1771,647,52,35,2193,737,2197,1011,354,10,1244,1782,3253,2785,2699,2346,128,283,1504,2609,2065,1928,1792,1797,481,1524,484,2802,41,2634,1548,623,175,2824,2258,370,313,638,2426,2755
0.053860976884978005,-0.3380597911426015,-0.3380597911426015,-0.388392317630512,0.24312104666747653,1.6654484983059537,-0.5412682933157936,-0.5412682933157936,-0.23831786606746352,0.2897820267826493,0.053860976884978005,1.046822951105993,-0.3380597911426015,-0.23831786606746352,-0.18889877938207092,-0.13977468780074367,-0.09094104587744528,0.38234507015049096,2.431534530000306,3.0039248680970876,-0.23831786606746352,0.3361888423900969,-0.23831786606746352,0.19620224214011292,0.6542105287099975,6.0439644005275905,0.10157608769830284,-0.09094104587744528,-1.2356850843636273,-0.4899972174116964,-0.43903817143719953,-0.28803660939734893,1.381940746478781,0.7870267798407822,0.005872513874080369,-0.388392317630512,-0.18889877938207092,-0.13977468780074367,-0.09094104587744528,-0.09094104587744528,0.5193447980380466,0.005872513874080369,0.5193447980380466,-0.4899972174116964,2.899060884241353,-0.388392317630512,0.005872513874080369,0.4282542060735226,1.1317712009042973,-0.4899972174116964,-0.23831786606746352,0.6542105287099975,0.7429774213920438,0.4282542060735226,-0.28803660939734893,-0.43903817143719953
3,367
Ub specific processing proteases
12
78
2.212487
0.026933
P60900,Q70CQ2,P28074,Q13309,P21796,P20618,P49721,Q9UPU5,Q96K76,P28072,Q8TAF3,P45880
Processes and pathways
Reactome Pathways
msigdb_reactome
128,287,35,232,100,192,10,16,254,52,251,56
1319,2436,2437,2567,2440,875,3123,2766,2846,1097,383,997,728,1343,192,100,2458,2179,2041,1895,1771,647,52,35,2193,2197,56,2599,1011,354,10,1244,740,1782,2699,128,283,1504,2609,2065,1792,3229,3194,1797,232,749,1380,1258,750,2228,481,1524,2713,2802,287,1405,1162,679,251,2394,952,2252,851,254,1690,2824,2258,2539,2959,638,2426,457,16,2836,980,573,2150,3250
0.053860976884978005,-0.3380597911426015,-0.3380597911426015,-0.388392317630512,-0.3380597911426015,0.24312104666747653,-0.8553842121388305,-0.4899972174116964,-0.5412682933157936,0.14902186735214557,0.6094870655900769,0.19620224214011292,0.3361888423900969,0.053860976884978005,1.046822951105993,1.6254733747117993,-0.3380597911426015,-0.23831786606746352,-0.18889877938207092,-0.13977468780074367,-0.09094104587744528,0.38234507015049096,2.431534530000306,3.0039248680970876,-0.23831786606746352,-0.23831786606746352,2.394640025697565,-0.388392317630512,0.19620224214011292,0.6542105287099975,6.0439644005275905,0.10157608769830284,0.3361888423900969,-0.09094104587744528,-0.43903817143719953,1.381940746478781,0.7870267798407822,0.005872513874080369,-0.388392317630512,-0.18889877938207092,-0.09094104587744528,-1.1255266262233685,-1.0165649980725264,-0.09094104587744528,0.9178727874245445,0.3361888423900969,0.053860976884978005,0.10157608769830284,0.3361888423900969,-0.23831786606746352,0.5193447980380466,0.005872513874080369,-0.43903817143719953,-0.4899972174116964,0.7870267798407822,0.053860976884978005,0.14902186735214557,0.38234507015049096,0.8744716799879915,-0.28803660939734893,0.24312104666747653,-0.23831786606746352,0.2897820267826493,0.8744716799879915,-0.04239342030431858,-0.4899972174116964,-0.23831786606746352,-0.3380597911426015,-0.5928502525010018,0.4282542060735226,-0.28803660939734893,0.5645328647779381,5.023653846020728,-0.4899972174116964,0.24312104666747653,0.4739196680085796,-0.18889877938207092,-1.1804567452748522
3,367
Runx1 regulates transcription of genes involved in differentiation of hscs
8
42
2.199906
0.027814
P60900,P28074,P16104,P20618,P49721,P62805,P28072,P61289
Processes and pathways
Reactome Pathways
msigdb_reactome
128,35,158,192,10,171,52,283
1319,2436,2437,2567,875,2846,158,1343,192,2458,2179,2041,1895,1771,647,52,35,2193,2197,1011,354,10,2981,1244,2699,128,283,1504,2609,2065,171,3193,1792,1797,2620,481,1524,1174,2824,2258,638,2426
0.053860976884978005,-0.3380597911426015,-0.3380597911426015,-0.388392317630512,0.24312104666747653,-0.5412682933157936,1.2159277397438069,0.053860976884978005,1.046822951105993,-0.3380597911426015,-0.23831786606746352,-0.18889877938207092,-0.13977468780074367,-0.09094104587744528,0.38234507015049096,2.431534530000306,3.0039248680970876,-0.23831786606746352,-0.23831786606746352,0.19620224214011292,0.6542105287099975,6.0439644005275905,-0.6447419635510961,0.10157608769830284,-0.43903817143719953,1.381940746478781,0.7870267798407822,0.005872513874080369,-0.388392317630512,-0.18889877938207092,1.1317712009042973,-1.0165649980725264,-0.09094104587744528,-0.09094104587744528,-0.388392317630512,0.5193447980380466,0.005872513874080369,0.14902186735214557,-0.4899972174116964,-0.23831786606746352,0.4282542060735226,-0.28803660939734893
3,367
Abnormality of corneal stroma
8
17
2.197302
0.027999
O43933,P04062,O43505,P10619,Q92889,Q6P4I2,P34913,Q16625
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
98,99,70,61,253,123,179,301
70,98,99,61,2919,819,1108,179,353,1122,924,3195,301,123,253,795,706
2.0177872441211355,1.6254733747117993,1.6254733747117993,2.283114015588119,-0.5928502525010018,0.2897820267826493,0.14902186735214557,1.0893972532895093,0.6542105287099975,0.14902186735214557,0.24312104666747653,-1.0165649980725264,0.7429774213920438,1.422977916752635,0.8744716799879915,0.3361888423900969,0.38234507015049096
3,367
Orc1 removal from chromatin
11
49
2.195492
0.028128
P60900,P28074,Q13309,P20618,P49721,Q99741,P49720,P28072,Q9UBD5,P61289,P63208
Processes and pathways
Reactome Pathways
msigdb_reactome
128,35,232,192,10,498,354,52,221,283,394
1319,2436,2437,2567,875,1586,2846,1343,192,1229,2325,2458,2179,2041,1895,1771,647,52,35,2190,1618,2046,2193,2197,1011,354,10,1496,1244,2699,128,283,1504,2609,2065,394,1792,1797,232,3241,1934,481,1524,2824,2258,498,221,638,2426
0.053860976884978005,-0.3380597911426015,-0.3380597911426015,-0.388392317630512,0.24312104666747653,-0.04239342030431858,-0.5412682933157936,0.053860976884978005,1.046822951105993,0.10157608769830284,-0.28803660939734893,-0.3380597911426015,-0.23831786606746352,-0.18889877938207092,-0.13977468780074367,-0.09094104587744528,0.38234507015049096,2.431534530000306,3.0039248680970876,-0.23831786606746352,-0.04239342030431858,-0.18889877938207092,-0.23831786606746352,-0.23831786606746352,0.19620224214011292,0.6542105287099975,6.0439644005275905,0.005872513874080369,0.10157608769830284,-0.43903817143719953,1.381940746478781,0.7870267798407822,0.005872513874080369,-0.388392317630512,-0.18889877938207092,0.6094870655900769,-0.09094104587744528,-0.09094104587744528,0.9178727874245445,-1.1804567452748522,-0.13977468780074367,0.5193447980380466,0.005872513874080369,-0.4899972174116964,-0.23831786606746352,0.5193447980380466,0.961063282020524,0.4282542060735226,-0.28803660939734893
3,367
Asymmetric localization of pcp proteins
6
37
2.175632
0.029583
P60900,P28074,P20618,P49721,P28072,P61289
Processes and pathways
Reactome Pathways
msigdb_reactome
128,35,192,10,52,283
1319,2436,2437,2567,875,2846,1343,192,2458,2179,2041,1895,1771,647,52,35,2193,2197,1011,354,10,1244,2699,128,283,1504,2609,2065,1792,1797,1802,481,1524,2824,2258,638,2426
0.053860976884978005,-0.3380597911426015,-0.3380597911426015,-0.388392317630512,0.24312104666747653,-0.5412682933157936,0.053860976884978005,1.046822951105993,-0.3380597911426015,-0.23831786606746352,-0.18889877938207092,-0.13977468780074367,-0.09094104587744528,0.38234507015049096,2.431534530000306,3.0039248680970876,-0.23831786606746352,-0.23831786606746352,0.19620224214011292,0.6542105287099975,6.0439644005275905,0.10157608769830284,-0.43903817143719953,1.381940746478781,0.7870267798407822,0.005872513874080369,-0.388392317630512,-0.18889877938207092,-0.09094104587744528,-0.09094104587744528,-0.09094104587744528,0.5193447980380466,0.005872513874080369,-0.4899972174116964,-0.23831786606746352,0.4282542060735226,-0.28803660939734893
3,367
Regulation of synapse structure or activity
9
38
2.175446
0.029597
Q9UQB8,Q4V328,P05067,Q9UJX6,Q14118,P50897,Q7L576,Q9UQ16,P19022
Processes and pathways
GO Biological process
msigdb_gobp
0,246,190,317,263,261,305,187,294
1459,190,324,2680,1001,294,2457,1909,908,261,2346,1125,2703,1127,2350,1513,1928,3071,3229,2798,668,263,1650,2079,2624,2085,246,305,2733,960,447,1562,2832,2552,317,187,0,800
0.005872513874080369,1.046822951105993,0.6987063152944422,-0.43903817143719953,0.19620224214011292,0.7429774213920438,-0.3380597911426015,-0.13977468780074367,0.24312104666747653,0.8308572620954069,-0.28803660939734893,0.14902186735214557,-0.43903817143719953,0.14902186735214557,-0.28803660939734893,0.005872513874080369,-0.13977468780074367,-0.7494501896778172,-1.1255266262233685,-0.4899972174116964,0.38234507015049096,0.8308572620954069,-0.04239342030431858,-0.18889877938207092,-0.388392317630512,-0.18889877938207092,0.8744716799879915,0.7429774213920438,-0.43903817143719953,0.24312104666747653,0.5645328647779381,0.005872513874080369,-0.4899972174116964,-0.3380597911426015,0.7429774213920438,1.0893972532895093,9.674117275578304,0.3361888423900969
3,367
Protease
21
120
2.175309
0.029607
P42785,Q9UIQ6,Q70CQ2,Q5BJF2,Q9BYT8,Q9HB40,Q8NHP8,P55786,Q9NZ08,P48147,Q2T9J0,P34913,P10619,P42892,P53634,P17812,O75844,O14773,Q8TCT9,Q96K76,P67812
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
3,19,287,24,154,28,29,159,47,170,49,179,61,63,328,325,87,319,235,254,241
1731,2013,2437,2843,319,874,1202,1736,1206,87,383,888,1472,1476,1217,61,2918,1224,1761,728,818,325,1227,2687,1345,2327,2778,2328,1615,179,733,2335,737,3,63,2599,170,2340,1244,740,594,1365,328,1919,1782,159,596,1632,915,241,3332,2486,2071,665,2616,3195,2619,2873,2228,2083,1655,3076,49,2238,1659,24,402,1664,1154,2940,1535,287,2511,1819,2812,486,2991,366,29,2389,2390,235,948,1548,2393,687,2731,1831,2252,954,851,1054,254,959,1690,961,2951,1177,2262,154,785,786,28,1564,3005,701,47,2136,3145,3312,2141,19,1863,457,2432,3250,514,3012,2755,575
-0.09094104587744528,-0.18889877938207092,-0.3380597911426015,-0.5412682933157936,0.6987063152944422,0.24312104666747653,0.10157608769830284,-0.09094104587744528,0.10157608769830284,1.7052535001830216,0.6094870655900769,0.24312104666747653,0.005872513874080369,0.005872513874080369,0.10157608769830284,2.283114015588119,-0.5928502525010018,0.10157608769830284,-0.09094104587744528,0.3361888423900969,0.2897820267826493,0.6987063152944422,0.10157608769830284,-0.43903817143719953,0.053860976884978005,-0.28803660939734893,-0.4899972174116964,-0.28803660939734893,-0.04239342030431858,1.0893972532895093,0.3361888423900969,-0.28803660939734893,0.3361888423900969,7.767211111294991,2.132393733047149,-0.388392317630512,1.1317712009042973,-0.28803660939734893,0.10157608769830284,0.3361888423900969,0.4282542060735226,0.053860976884978005,0.6987063152944422,-0.13977468780074367,-0.09094104587744528,1.2159277397438069,0.4282542060735226,-0.04239342030431858,0.24312104666747653,0.8744716799879915,-2.0992610771115365,-0.3380597911426015,-0.18889877938207092,0.38234507015049096,-0.388392317630512,-1.0165649980725264,-0.388392317630512,-0.5412682933157936,-0.23831786606746352,-0.18889877938207092,-0.04239342030431858,-0.7494501896778172,2.5413946027810876,-0.23831786606746352,-0.04239342030431858,3.9345059665079796,0.6094870655900769,-0.04239342030431858,0.14902186735214557,-0.5928502525010018,0.005872513874080369,0.7870267798407822,-0.3380597911426015,-0.09094104587744528,-0.4899972174116964,0.5193447980380466,-0.6447419635510961,0.6542105287099975,3.3794741768918657,-0.28803660939734893,-0.28803660939734893,0.9178727874245445,0.24312104666747653,0.005872513874080369,-0.28803660939734893,0.38234507015049096,-0.43903817143719953,-0.09094104587744528,-0.23831786606746352,0.24312104666747653,0.2897820267826493,0.19620224214011292,0.8744716799879915,0.24312104666747653,-0.04239342030431858,0.24312104666747653,-0.5928502525010018,0.14902186735214557,-0.23831786606746352,1.257715066848026,0.3361888423900969,0.3361888423900969,3.4129471399409548,0.005872513874080369,-0.6447419635510961,0.38234507015049096,2.5777445433602932,-0.18889877938207092,-0.8553842121388305,-1.6881333429715428,-0.18889877938207092,4.4014392320994515,-0.09094104587744528,0.5645328647779381,-0.28803660939734893,-1.1804567452748522,0.5193447980380466,-0.6447419635510961,-0.43903817143719953,0.4739196680085796
3,367
Cation transmembrane transporter activity
15
53
2.173253
0.029761
P30825,O75964,O43772,P21283,Q9UI12,Q9HC21,O95202,Q70HW3,P56385,Q9HD20,Q9UDW1,Q00325,P36542,P21281,P61421
Functions
GO Molecular function
msigdb_gomf
212,33,2,588,372,413,519,45,529,51,118,478,297,121,532
2,722,584,33,519,1471,1597,1102,1334,2168,2450,890,1336,2319,2585,1000,1226,2588,2322,121,588,1347,2777,212,1615,297,1905,1492,3191,2338,2208,742,529,532,1249,478,3156,1033,755,1397,45,1952,953,3163,1693,2898,3281,1438,413,51,118,372,2006
8.462226464311355,0.3361888423900969,0.4282542060735226,3.0386401585275027,0.4739196680085796,0.005872513874080369,-0.04239342030431858,0.14902186735214557,0.053860976884978005,-0.23831786606746352,-0.3380597911426015,0.24312104666747653,0.053860976884978005,-0.28803660939734893,-0.388392317630512,0.19620224214011292,0.10157608769830284,-0.388392317630512,-0.28803660939734893,1.422977916752635,0.4282542060735226,0.053860976884978005,-0.4899972174116964,0.961063282020524,-0.04239342030431858,0.7429774213920438,-0.13977468780074367,0.005872513874080369,-1.0165649980725264,-0.28803660939734893,-0.23831786606746352,0.3361888423900969,0.4739196680085796,0.4739196680085796,0.10157608769830284,0.5193447980380466,-0.908808220790615,0.19620224214011292,0.3361888423900969,0.053860976884978005,2.7575257190991964,-0.13977468780074367,0.24312104666747653,-0.908808220790615,-0.04239342030431858,-0.5412682933157936,-1.3470325431471153,0.053860976884978005,0.6094870655900769,2.5049104893301823,1.463832977402664,0.6542105287099975,-0.13977468780074367
3,367
Alcohol binding
7
17
2.172116
0.029847
Q14108,P21796,P30536,P61916,P45880,O15118,Q9H4L5
Functions
GO Molecular function
msigdb_gomf
164,100,113,149,56,125,341
807,125,3055,885,2450,100,1607,1900,113,429,56,149,164,1145,1296,2535,341
0.2897820267826493,1.381940746478781,-0.7494501896778172,0.24312104666747653,-0.3380597911426015,1.6254733747117993,-0.04239342030431858,-0.13977468780074367,1.463832977402664,0.5645328647779381,2.394640025697565,1.257715066848026,1.1739472326847418,0.14902186735214557,0.10157608769830284,-0.3380597911426015,0.6987063152944422
3,367
Target SNARE coiled-coil homology domain [IPR000727]
6
7
2.166387
0.030282
Q86Y82,O15400,Q9UNK0,O95721,Q12846,Q13190
Sequence
InterPro Domain
interpro_domain
196,276,177,228,114,396
276,516,228,114,396,196,177
0.7870267798407822,0.4739196680085796,0.9178727874245445,1.463832977402664,0.6094870655900769,1.046822951105993,1.1317712009042973
3,367
Cross presentation of soluble exogenous antigens endosomes
6
36
2.16145
0.030661
P60900,P28074,P20618,P49721,P28072,P61289
Processes and pathways
Reactome Pathways
msigdb_reactome
128,35,192,10,52,283
1319,2436,2437,2567,875,2846,1343,192,2458,2179,2041,1895,1771,647,52,35,2193,2197,1011,354,10,1244,2699,128,283,1504,2609,2065,1792,1797,481,1524,2824,2258,638,2426
0.053860976884978005,-0.3380597911426015,-0.3380597911426015,-0.388392317630512,0.24312104666747653,-0.5412682933157936,0.053860976884978005,1.046822951105993,-0.3380597911426015,-0.23831786606746352,-0.18889877938207092,-0.13977468780074367,-0.09094104587744528,0.38234507015049096,2.431534530000306,3.0039248680970876,-0.23831786606746352,-0.23831786606746352,0.19620224214011292,0.6542105287099975,6.0439644005275905,0.10157608769830284,-0.43903817143719953,1.381940746478781,0.7870267798407822,0.005872513874080369,-0.388392317630512,-0.18889877938207092,-0.09094104587744528,-0.09094104587744528,0.5193447980380466,0.005872513874080369,-0.4899972174116964,-0.23831786606746352,0.4282542060735226,-0.28803660939734893
3,367
Degradation of axin
6
36
2.16145
0.030661
P60900,P28074,P20618,P49721,P28072,P61289
Processes and pathways
Reactome Pathways
msigdb_reactome
128,35,192,10,52,283
1319,2436,2437,2567,875,2846,1343,192,2458,2179,2041,1895,1771,647,52,35,2193,2197,1011,354,10,1244,2699,128,283,1504,2609,2065,1792,1797,481,1524,2824,2258,638,2426
0.053860976884978005,-0.3380597911426015,-0.3380597911426015,-0.388392317630512,0.24312104666747653,-0.5412682933157936,0.053860976884978005,1.046822951105993,-0.3380597911426015,-0.23831786606746352,-0.18889877938207092,-0.13977468780074367,-0.09094104587744528,0.38234507015049096,2.431534530000306,3.0039248680970876,-0.23831786606746352,-0.23831786606746352,0.19620224214011292,0.6542105287099975,6.0439644005275905,0.10157608769830284,-0.43903817143719953,1.381940746478781,0.7870267798407822,0.005872513874080369,-0.388392317630512,-0.18889877938207092,-0.09094104587744528,-0.09094104587744528,0.5193447980380466,0.005872513874080369,-0.4899972174116964,-0.23831786606746352,0.4282542060735226,-0.28803660939734893
3,367
SLC25 family of mitochondrial transporters
8
19
2.152168
0.031384
O43772,Q9HC21,P12236,Q9H2D1,Q9NZJ7,Q70HW3,Q9BSK2,Q00325
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
2,413,470,105,315,45,500,478
2,722,1095,1102,2585,470,1917,478,533,938,45,500,105,3281,413,315,1998,867,2012
8.462226464311355,0.3361888423900969,0.14902186735214557,0.14902186735214557,-0.388392317630512,0.5193447980380466,-0.13977468780074367,0.5193447980380466,0.4739196680085796,0.24312104666747653,2.7575257190991964,0.5193447980380466,1.5450050959353323,-1.3470325431471153,0.6094870655900769,0.7429774213920438,-0.13977468780074367,0.2897820267826493,-0.13977468780074367
3,367
Mitochondrial carrier domain superfamily [IPR023395]
8
19
2.152168
0.031384
O43772,Q9HC21,P12236,Q9H2D1,Q9NZJ7,Q70HW3,Q9BSK2,Q00325
Sequence
InterPro Superfamily
interpro_homologous_superfamily
2,413,470,105,315,45,500,478
2,722,1095,1102,2585,470,1917,478,533,938,45,500,105,3281,413,315,1998,867,2012
8.462226464311355,0.3361888423900969,0.14902186735214557,0.14902186735214557,-0.388392317630512,0.5193447980380466,-0.13977468780074367,0.5193447980380466,0.4739196680085796,0.24312104666747653,2.7575257190991964,0.5193447980380466,1.5450050959353323,-1.3470325431471153,0.6094870655900769,0.7429774213920438,-0.13977468780074367,0.2897820267826493,-0.13977468780074367
3,367
Mitochondrial substrate/solute carrier [IPR018108]
8
19
2.152168
0.031384
O43772,Q9HC21,P12236,Q9H2D1,Q9NZJ7,Q70HW3,Q9BSK2,Q00325
Sequence
InterPro Repeat
interpro_repeat
2,413,470,105,315,45,500,478
2,722,1095,1102,2585,470,1917,478,533,938,45,500,105,3281,413,315,1998,867,2012
8.462226464311355,0.3361888423900969,0.14902186735214557,0.14902186735214557,-0.388392317630512,0.5193447980380466,-0.13977468780074367,0.5193447980380466,0.4739196680085796,0.24312104666747653,2.7575257190991964,0.5193447980380466,1.5450050959353323,-1.3470325431471153,0.6094870655900769,0.7429774213920438,-0.13977468780074367,0.2897820267826493,-0.13977468780074367
3,367
Hormone metabolic process
7
26
2.148679
0.03166
O95470,Q53GQ0,P30536,Q9UBM7,O75844,Q9HB40,P42892
Processes and pathways
GO Biological process
msigdb_gobp
34,264,113,54,87,28,63
2571,87,34,1597,728,2037,1340,113,63,2695,2603,3240,2984,1145,1147,264,1041,308,2726,680,2396,1290,28,54,3211,2562
-0.388392317630512,1.7052535001830216,3.0039248680970876,-0.04239342030431858,0.3361888423900969,-0.18889877938207092,0.053860976884978005,1.463832977402664,2.132393733047149,-0.43903817143719953,-0.388392317630512,-1.1804567452748522,-0.6447419635510961,0.14902186735214557,0.14902186735214557,0.8308572620954069,0.19620224214011292,0.7429774213920438,-0.43903817143719953,0.38234507015049096,-0.28803660939734893,0.10157608769830284,3.4129471399409548,2.431534530000306,-1.0165649980725264,-0.3380597911426015
3,367
Ventricular tachycardia
6
14
2.144426
0.031999
O43772,P49748,Q99996,P23786,P19022,P04899
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
2,230,83,82,294,322
2,322,3224,3291,294,82,1907,1361,230,1142,616,83,412,1567
8.462226464311355,0.6987063152944422,-1.1255266262233685,-1.4595613570006674,0.7429774213920438,1.7843606013886042,-0.13977468780074367,0.053860976884978005,0.9178727874245445,0.14902186735214557,0.4282542060735226,1.7843606013886042,0.6094870655900769,0.005872513874080369
3,367
Vacuolar membrane
29
116
2.14423
0.032015
P42785,Q6IAA8,Q9P2R3,O75503,Q9UIQ6,P20645,Q8WTV0,O15260,P13473,O15400,Q14108,Q8IV08,Q9UNK0,Q96GC9,Q9NZJ7,Q9NXC5,P51148,P10619,Q16625,P42892,Q8N511,Q96RL7,P04062,Q9UI12,Q9Y2Q5,P27105,O95721,P21281,O15118
Localization
GO Cellular component
msigdb_gocc
3,266,418,134,19,23,25,379,389,276,164,37,177,174,315,451,298,61,301,63,95,216,99,372,374,104,228,121,125
1458,458,714,125,379,3265,276,2443,876,2301,2157,880,134,585,886,228,1213,99,815,2168,468,2450,890,1753,1477,1219,2318,61,426,2680,3025,389,23,121,588,1486,104,2462,2592,1905,1492,1620,2978,826,3,63,2337,298,1014,475,657,3128,1784,2787,1369,532,2213,1023,3192,920,2793,1377,3268,923,2796,606,164,1145,1033,301,266,37,1826,95,2246,1046,25,548,1547,683,3163,2525,956,1415,690,1834,174,960,216,2260,2117,2402,1182,1297,2409,2898,2736,2899,3091,2741,3006,451,315,702,2834,418,372,19,2662,3342,177,374,2560,3347,2006,1083
0.005872513874080369,0.5193447980380466,0.3361888423900969,1.381940746478781,0.6094870655900769,-1.2912106707426125,0.7870267798407822,-0.3380597911426015,0.24312104666747653,-0.28803660939734893,-0.23831786606746352,0.24312104666747653,1.3407193358749927,0.4282542060735226,0.24312104666747653,0.9178727874245445,0.10157608769830284,1.6254733747117993,0.2897820267826493,-0.23831786606746352,0.5193447980380466,-0.3380597911426015,0.24312104666747653,-0.09094104587744528,0.005872513874080369,0.10157608769830284,-0.28803660939734893,2.283114015588119,0.5645328647779381,-0.43903817143719953,-0.6969423099361801,0.6094870655900769,4.123694916854529,1.422977916752635,0.4282542060735226,0.005872513874080369,1.5450050959353323,-0.3380597911426015,-0.388392317630512,-0.13977468780074367,0.005872513874080369,-0.04239342030431858,-0.6447419635510961,0.2897820267826493,7.767211111294991,2.132393733047149,-0.28803660939734893,0.7429774213920438,0.19620224214011292,0.5193447980380466,0.38234507015049096,-0.8553842121388305,-0.09094104587744528,-0.4899972174116964,0.053860976884978005,0.4739196680085796,-0.23831786606746352,0.19620224214011292,-1.0165649980725264,0.24312104666747653,-0.4899972174116964,0.053860976884978005,-1.2912106707426125,0.24312104666747653,-0.4899972174116964,0.4282542060735226,1.1739472326847418,0.14902186735214557,0.19620224214011292,0.7429774213920438,0.8308572620954069,2.969090607110795,-0.09094104587744528,1.6654484983059537,-0.23831786606746352,0.19620224214011292,3.6115632124813404,0.4739196680085796,0.005872513874080369,0.38234507015049096,-0.908808220790615,-0.3380597911426015,0.24312104666747653,0.053860976884978005,0.38234507015049096,-0.09094104587744528,1.1317712009042973,0.24312104666747653,0.961063282020524,-0.23831786606746352,-0.18889877938207092,-0.28803660939734893,0.14902186735214557,0.10157608769830284,-0.28803660939734893,-0.5412682933157936,-0.43903817143719953,-0.5412682933157936,-0.7494501896778172,-0.43903817143719953,-0.6447419635510961,0.5645328647779381,0.7429774213920438,0.38234507015049096,-0.4899972174116964,0.6094870655900769,0.6542105287099975,4.4014392320994515,-0.388392317630512,-2.340455914597067,1.1317712009042973,0.6542105287099975,-0.3380597911426015,-2.710654339272441,-0.13977468780074367,0.19620224214011292
3,367
Central nervous system cyst
13
63
2.134762
0.03278
Q6P4I2,O43933,P80404,O43505,Q15125,Q14118,Q2M1P5,Q12768,P23786,Q9UBM7,P07437,Q15031,P21281
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
123,98,36,70,74,263,205,144,82,54,324,286,121
1322,986,2020,70,3212,1872,98,3019,2769,519,387,324,3024,817,121,82,898,1905,733,1357,1492,2056,1245,1784,1125,1370,36,1926,144,1134,3073,263,286,74,1808,205,2240,123,2880,543,2389,1048,2524,952,1285,1687,1053,2397,1421,1692,2262,1557,1423,1845,2270,2131,54,2659,705,2963,2006,803,2565
0.053860976884978005,0.19620224214011292,-0.18889877938207092,2.0177872441211355,-1.070895711677453,-0.13977468780074367,1.6254733747117993,-0.6969423099361801,-0.4899972174116964,0.4739196680085796,0.6094870655900769,0.6987063152944422,-0.6969423099361801,0.2897820267826493,1.422977916752635,1.7843606013886042,0.24312104666747653,-0.13977468780074367,0.3361888423900969,0.053860976884978005,0.005872513874080369,-0.18889877938207092,0.10157608769830284,-0.09094104587744528,0.14902186735214557,0.053860976884978005,2.969090607110795,-0.13977468780074367,1.2993115136492674,0.14902186735214557,-0.7494501896778172,0.8308572620954069,0.7870267798407822,1.9792784396533925,-0.09094104587744528,1.004045806677848,-0.23831786606746352,1.422977916752635,-0.5412682933157936,0.4739196680085796,-0.28803660939734893,0.19620224214011292,-0.3380597911426015,0.24312104666747653,0.10157608769830284,-0.04239342030431858,0.19620224214011292,-0.28803660939734893,0.053860976884978005,-0.04239342030431858,-0.23831786606746352,0.005872513874080369,0.053860976884978005,-0.09094104587744528,-0.23831786606746352,-0.18889877938207092,2.431534530000306,-0.388392317630512,0.38234507015049096,-0.5928502525010018,-0.13977468780074367,0.3361888423900969,-0.3380597911426015
3,367
Heart block
8
23
2.133495
0.032884
O43772,Q9H490,P49748,Q99996,P23786,P19022,P04899,P50402
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
2,313,230,83,82,294,322,214
2,1094,3190,322,998,3224,294,82,1905,1492,1361,230,214,1370,2984,3268,1932,2230,616,1168,83,412,313
8.462226464311355,0.14902186735214557,-1.0165649980725264,0.6987063152944422,0.19620224214011292,-1.1255266262233685,0.7429774213920438,1.7843606013886042,-0.13977468780074367,0.005872513874080369,0.053860976884978005,0.9178727874245445,0.961063282020524,0.053860976884978005,-0.6447419635510961,-1.2912106707426125,-0.13977468780074367,-0.23831786606746352,0.4282542060735226,0.14902186735214557,1.7843606013886042,0.6094870655900769,0.7429774213920438
3,367
Pcp ce pathway
6
47
2.132171
0.032993
P60900,P28074,P20618,P49721,P28072,P61289
Processes and pathways
Reactome Pathways
msigdb_reactome
128,35,192,10,52,283
1319,2436,2437,2567,875,2846,886,1213,1103,1219,1220,1343,192,2458,2179,2041,1895,1771,647,52,35,2193,2197,1011,354,10,1244,657,2699,128,283,1504,2609,2065,1787,1023,920,1792,1797,1802,481,1524,1415,2824,2258,638,2426
0.053860976884978005,-0.3380597911426015,-0.3380597911426015,-0.388392317630512,0.24312104666747653,-0.5412682933157936,0.24312104666747653,0.10157608769830284,0.14902186735214557,0.10157608769830284,0.10157608769830284,0.053860976884978005,1.046822951105993,-0.3380597911426015,-0.23831786606746352,-0.18889877938207092,-0.13977468780074367,-0.09094104587744528,0.38234507015049096,2.431534530000306,3.0039248680970876,-0.23831786606746352,-0.23831786606746352,0.19620224214011292,0.6542105287099975,6.0439644005275905,0.10157608769830284,0.38234507015049096,-0.43903817143719953,1.381940746478781,0.7870267798407822,0.005872513874080369,-0.388392317630512,-0.18889877938207092,-0.09094104587744528,0.19620224214011292,0.24312104666747653,-0.09094104587744528,-0.09094104587744528,-0.09094104587744528,0.5193447980380466,0.005872513874080369,0.053860976884978005,-0.4899972174116964,-0.23831786606746352,0.4282542060735226,-0.28803660939734893
3,367
Abnormal enchondral ossification
12
30
2.131229
0.03307
Q9NUQ7,O43933,Q8NCM8,O95202,Q9UG56,Q15125,Q2M1P5,O96028,Q9UBM7,Q14739,Q5F1R6,Q96L58
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
130,98,543,519,316,74,205,387,54,151,247,215
2669,2673,98,1739,882,519,387,1222,2176,733,1358,530,2059,3073,151,2711,74,1938,205,247,543,773,958,1172,215,1295,130,54,316,2563
-0.43903817143719953,-0.43903817143719953,1.6254733747117993,-0.09094104587744528,0.24312104666747653,0.4739196680085796,0.6094870655900769,0.10157608769830284,-0.23831786606746352,0.3361888423900969,0.053860976884978005,0.4739196680085796,-0.18889877938207092,-0.7494501896778172,1.257715066848026,-0.43903817143719953,1.9792784396533925,-0.13977468780074367,1.004045806677848,0.8744716799879915,0.4739196680085796,0.3361888423900969,0.24312104666747653,0.14902186735214557,0.961063282020524,0.10157608769830284,1.381940746478781,2.431534530000306,0.7429774213920438,-0.3380597911426015
3,367
Membrane lipid metabolic process
10
35
2.130173
0.033157
O95470,Q8NCC3,Q9H490,P04062,Q96S52,Q06136,P50897,Q96G23,Q8NBX0,Q99735
Processes and pathways
GO Biological process
msigdb_gobp
34,4,313,99,175,262,261,20,57,217
578,2019,3055,34,99,2314,998,3275,468,3327,2919,1889,1110,821,822,261,2352,262,2986,3195,1812,57,4,1548,623,20,175,217,3309,313,793,794,315,1302,702
0.4282542060735226,-0.18889877938207092,-0.7494501896778172,3.0039248680970876,1.6254733747117993,-0.28803660939734893,0.19620224214011292,-1.3470325431471153,0.5193447980380466,-1.9803639244210636,-0.5928502525010018,-0.13977468780074367,0.14902186735214557,0.2897820267826493,0.2897820267826493,0.8308572620954069,-0.28803660939734893,0.8308572620954069,-0.6447419635510961,-1.0165649980725264,-0.09094104587744528,2.3576060307697295,7.298411945543759,0.005872513874080369,0.4282542060735226,4.309639278406814,1.1317712009042973,0.961063282020524,-1.6305533263740417,0.7429774213920438,0.3361888423900969,0.3361888423900969,0.7429774213920438,0.10157608769830284,0.38234507015049096
3,367
Auf1 hnrnp d0 binds and destabilizes mrna
6
41
2.127216
0.033402
P60900,P28074,P20618,P49721,P28072,P61289
Processes and pathways
Reactome Pathways
msigdb_reactome
128,35,192,10,52,283
1319,2436,2437,2567,875,2846,2166,2680,1760,1343,192,2458,2179,2041,1895,1771,647,52,35,2193,2197,1011,354,10,1244,2699,128,283,1504,2609,2065,1513,1792,1797,2363,481,1524,2824,2258,638,2426
0.053860976884978005,-0.3380597911426015,-0.3380597911426015,-0.388392317630512,0.24312104666747653,-0.5412682933157936,-0.23831786606746352,-0.43903817143719953,-0.09094104587744528,0.053860976884978005,1.046822951105993,-0.3380597911426015,-0.23831786606746352,-0.18889877938207092,-0.13977468780074367,-0.09094104587744528,0.38234507015049096,2.431534530000306,3.0039248680970876,-0.23831786606746352,-0.23831786606746352,0.19620224214011292,0.6542105287099975,6.0439644005275905,0.10157608769830284,-0.43903817143719953,1.381940746478781,0.7870267798407822,0.005872513874080369,-0.388392317630512,-0.18889877938207092,0.005872513874080369,-0.09094104587744528,-0.09094104587744528,-0.28803660939734893,0.5193447980380466,0.005872513874080369,-0.4899972174116964,-0.23831786606746352,0.4282542060735226,-0.28803660939734893
3,367
Degradation of dvl
6
37
2.124799
0.033603
P60900,P28074,P20618,P49721,P28072,P61289
Processes and pathways
Reactome Pathways
msigdb_reactome
128,35,192,10,52,283
1319,2436,2437,2567,875,2846,1343,192,2458,2179,2041,1895,1771,647,52,35,2193,2197,1011,354,10,1244,2699,128,283,1504,2609,2065,1792,1797,2492,481,1524,2824,2258,638,2426
0.053860976884978005,-0.3380597911426015,-0.3380597911426015,-0.388392317630512,0.24312104666747653,-0.5412682933157936,0.053860976884978005,1.046822951105993,-0.3380597911426015,-0.23831786606746352,-0.18889877938207092,-0.13977468780074367,-0.09094104587744528,0.38234507015049096,2.431534530000306,3.0039248680970876,-0.23831786606746352,-0.23831786606746352,0.19620224214011292,0.6542105287099975,6.0439644005275905,0.10157608769830284,-0.43903817143719953,1.381940746478781,0.7870267798407822,0.005872513874080369,-0.388392317630512,-0.18889877938207092,-0.09094104587744528,-0.09094104587744528,-0.3380597911426015,0.5193447980380466,0.005872513874080369,-0.4899972174116964,-0.23831786606746352,0.4282542060735226,-0.28803660939734893
3,367
Regulation of ras by gaps
6
37
2.124799
0.033603
P60900,P28074,P20618,P49721,P28072,P61289
Processes and pathways
Reactome Pathways
msigdb_reactome
128,35,192,10,52,283
1319,2436,2437,2567,875,2846,1343,192,2458,2179,2041,1895,1771,647,52,35,2193,2197,1011,354,10,1244,2699,128,283,1504,2609,2065,1792,1797,2492,481,1524,2824,2258,638,2426
0.053860976884978005,-0.3380597911426015,-0.3380597911426015,-0.388392317630512,0.24312104666747653,-0.5412682933157936,0.053860976884978005,1.046822951105993,-0.3380597911426015,-0.23831786606746352,-0.18889877938207092,-0.13977468780074367,-0.09094104587744528,0.38234507015049096,2.431534530000306,3.0039248680970876,-0.23831786606746352,-0.23831786606746352,0.19620224214011292,0.6542105287099975,6.0439644005275905,0.10157608769830284,-0.43903817143719953,1.381940746478781,0.7870267798407822,0.005872513874080369,-0.388392317630512,-0.18889877938207092,-0.09094104587744528,-0.09094104587744528,-0.3380597911426015,0.5193447980380466,0.005872513874080369,-0.4899972174116964,-0.23831786606746352,0.4282542060735226,-0.28803660939734893
3,367
Endoplasmic reticulum golgi intermediate compartment membrane
12
22
2.122232
0.033818
O95070,Q9BVK6,Q08379,Q96GC9,O15498,P53634,Q12907,O15260,P51572,Q8N511,Q13190,Q9Y282
Localization
GO Cellular component
msigdb_gocc
423,558,75,174,579,328,150,379,393,95,396,31
379,579,2969,1466,423,3176,1349,1777,1012,393,328,75,601,150,396,1263,95,174,558,1062,31,3008
0.6094870655900769,0.4282542060735226,-0.6447419635510961,0.005872513874080369,0.5645328647779381,-0.9625354940644615,0.053860976884978005,-0.09094104587744528,0.19620224214011292,0.6094870655900769,0.6987063152944422,1.9017911284204507,0.4282542060735226,1.257715066848026,0.6094870655900769,0.10157608769830284,1.6654484983059537,1.1317712009042973,0.4739196680085796,0.19620224214011292,3.2104683932450104,-0.6447419635510961
3,367
Histone methylation
7
63
2.122032
0.033835
P16403,P10412,P16402,Q9Y3Y2,Q9H7B4,Q9BV86,Q9Y5B6
Processes and pathways
GO Biological process
msigdb_gobp
191,39,109,44,14,15,90
2297,1323,1088,1089,1587,463,1876,387,3190,39,109,191,3126,1606,1348,898,590,905,1775,1624,2203,2062,3193,1134,749,2361,2618,2495,2500,2365,1936,1663,1533,1940,1156,2378,2880,1400,2813,676,1164,252,2641,2254,1419,853,1694,15,1295,2269,3280,2408,2953,14,1710,2279,456,1451,2143,44,2293,1455,90
-0.28803660939734893,0.053860976884978005,0.14902186735214557,0.14902186735214557,-0.04239342030431858,0.5193447980380466,-0.13977468780074367,0.6094870655900769,-1.0165649980725264,2.9341363071598647,1.5045080195895706,1.046822951105993,-0.8553842121388305,-0.04239342030431858,0.053860976884978005,0.24312104666747653,0.4282542060735226,0.24312104666747653,-0.09094104587744528,-0.04239342030431858,-0.23831786606746352,-0.18889877938207092,-1.0165649980725264,0.14902186735214557,0.3361888423900969,-0.28803660939734893,-0.388392317630512,-0.3380597911426015,-0.3380597911426015,-0.28803660939734893,-0.13977468780074367,-0.04239342030431858,0.005872513874080369,-0.13977468780074367,0.14902186735214557,-0.28803660939734893,-0.5412682933157936,0.053860976884978005,-0.4899972174116964,0.38234507015049096,0.14902186735214557,0.8744716799879915,-0.388392317630512,-0.23831786606746352,0.053860976884978005,0.2897820267826493,-0.04239342030431858,5.081159956656381,0.10157608769830284,-0.23831786606746352,-1.3470325431471153,-0.28803660939734893,-0.5928502525010018,5.364443360547954,-0.04239342030431858,-0.23831786606746352,0.5645328647779381,0.053860976884978005,-0.18889877938207092,2.7930967970410885,-0.23831786606746352,0.053860976884978005,1.7052535001830216
3,367
Secondary alcohol metabolic process
12
43
2.120128
0.033995
Q15800,P04062,P05067,Q15125,Q16850,Q9BQE5,P61916,Q9UBM7,Q14739,Q8WTV0,P34913,O15118
Processes and pathways
GO Biological process
msigdb_gobp
193,99,190,74,76,218,149,54,151,25,179,125
125,2570,1877,885,1595,99,190,2171,2587,1340,2687,179,429,2333,2979,652,738,230,1913,1630,2867,3240,149,2068,3331,431,2986,1141,2621,151,1145,3231,74,3035,3232,1938,193,76,25,2116,218,54,507
1.381940746478781,-0.388392317630512,-0.13977468780074367,0.24312104666747653,-0.04239342030431858,1.6254733747117993,1.046822951105993,-0.23831786606746352,-0.388392317630512,0.053860976884978005,-0.43903817143719953,1.0893972532895093,0.5645328647779381,-0.28803660939734893,-0.6447419635510961,0.38234507015049096,0.3361888423900969,0.9178727874245445,-0.13977468780074367,-0.04239342030431858,-0.5412682933157936,-1.1804567452748522,1.257715066848026,-0.18889877938207092,-2.0992610771115365,0.5645328647779381,-0.6447419635510961,0.14902186735214557,-0.388392317630512,1.257715066848026,0.14902186735214557,-1.1255266262233685,1.9792784396533925,-0.6969423099361801,-1.1255266262233685,-0.13977468780074367,1.046822951105993,1.9017911284204507,3.6115632124813404,-0.18889877938207092,0.961063282020524,2.431534530000306,0.5193447980380466
3,367
Inner mitochondrial membrane protein complex
12
69
2.119176
0.034076
O75964,P14406,Q96CU9,O60830,P09669,Q99595,Q9UDW1,O43676,Q9P0J0,Q13505,Q5XKP0,Q9BUR5
Localization
GO Cellular component
msigdb_gocc
33,58,7,12,112,18,118,55,220,26,194,198
3338,1460,420,55,12,1874,1465,3100,2025,584,33,3290,2027,3102,3349,1471,1334,1336,112,2319,470,1000,58,3060,1605,2322,2323,1345,1347,2777,2590,2330,1615,1489,297,2595,3191,2338,2864,527,742,529,26,839,1530,2370,609,1812,194,364,1948,3288,1952,7,1173,18,1838,3353,198,2538,1993,1567,274,220,118,510,3012,801,1457
-2.2192938988489903,0.005872513874080369,0.5645328647779381,2.394640025697565,5.531143228715627,-0.13977468780074367,0.005872513874080369,-0.8022645150247569,-0.18889877938207092,0.4282542060735226,3.0386401585275027,-1.4595613570006674,-0.18889877938207092,-0.8022645150247569,-2.8994916636965624,0.005872513874080369,0.053860976884978005,0.053860976884978005,1.463832977402664,-0.28803660939734893,0.5193447980380466,0.19620224214011292,2.320431162427097,-0.7494501896778172,-0.04239342030431858,-0.28803660939734893,-0.28803660939734893,0.053860976884978005,0.053860976884978005,-0.4899972174116964,-0.388392317630512,-0.28803660939734893,-0.04239342030431858,0.005872513874080369,0.7429774213920438,-0.388392317630512,-1.0165649980725264,-0.28803660939734893,-0.5412682933157936,0.4739196680085796,0.3361888423900969,0.4739196680085796,3.578720683939666,0.2897820267826493,0.005872513874080369,-0.28803660939734893,0.4282542060735226,-0.09094104587744528,1.046822951105993,0.6542105287099975,-0.13977468780074367,-1.403149751562867,-0.13977468780074367,6.510373398556831,0.14902186735214557,4.731666431481315,-0.09094104587744528,-3.5466505530698798,1.046822951105993,-0.3380597911426015,-0.13977468780074367,0.005872513874080369,0.8308572620954069,0.961063282020524,1.463832977402664,0.5193447980380466,-0.6447419635510961,0.3361888423900969,0.053860976884978005
3,367
Scf skp2 mediated degradation of p27 p21
8
40
2.095052
0.036166
P60900,P28074,Q13309,P20618,P49721,P49720,P28072,P61289
Processes and pathways
Reactome Pathways
msigdb_reactome
128,35,232,192,10,354,52,283
1319,2436,2437,2567,875,2846,469,1343,192,1229,2458,2179,2041,1895,1771,647,52,35,2193,2197,1011,354,10,1244,2699,128,283,1504,2609,2065,394,1792,1797,232,3241,1524,2824,2258,638,2426
0.053860976884978005,-0.3380597911426015,-0.3380597911426015,-0.388392317630512,0.24312104666747653,-0.5412682933157936,0.5193447980380466,0.053860976884978005,1.046822951105993,0.10157608769830284,-0.3380597911426015,-0.23831786606746352,-0.18889877938207092,-0.13977468780074367,-0.09094104587744528,0.38234507015049096,2.431534530000306,3.0039248680970876,-0.23831786606746352,-0.23831786606746352,0.19620224214011292,0.6542105287099975,6.0439644005275905,0.10157608769830284,-0.43903817143719953,1.381940746478781,0.7870267798407822,0.005872513874080369,-0.388392317630512,-0.18889877938207092,0.6094870655900769,-0.09094104587744528,-0.09094104587744528,0.9178727874245445,-1.1804567452748522,0.005872513874080369,-0.4899972174116964,-0.23831786606746352,0.4282542060735226,-0.28803660939734893
3,367
Dna replication pre initiation
13
61
2.089701
0.036645
P60900,P28074,P16104,P20618,P49721,Q99741,P49720,P62805,P28072,O60684,Q9UBD5,Q14997,P61289
Processes and pathways
Reactome Pathways
msigdb_reactome
128,35,158,192,10,498,354,171,52,382,221,481,283
1319,2436,2437,2567,875,1586,382,2846,1755,2174,158,1343,192,1229,2325,2458,2179,2041,1895,1612,1771,647,52,35,2190,1618,2046,2859,2193,2197,1011,1240,1495,354,10,1496,1244,3252,2699,1247,128,283,1504,2609,2065,171,1792,1516,1797,1934,2081,481,1524,2824,2258,498,2742,565,221,638,2426
0.053860976884978005,-0.3380597911426015,-0.3380597911426015,-0.388392317630512,0.24312104666747653,-0.04239342030431858,0.6094870655900769,-0.5412682933157936,-0.09094104587744528,-0.23831786606746352,1.2159277397438069,0.053860976884978005,1.046822951105993,0.10157608769830284,-0.28803660939734893,-0.3380597911426015,-0.23831786606746352,-0.18889877938207092,-0.13977468780074367,-0.04239342030431858,-0.09094104587744528,0.38234507015049096,2.431534530000306,3.0039248680970876,-0.23831786606746352,-0.04239342030431858,-0.18889877938207092,-0.5412682933157936,-0.23831786606746352,-0.23831786606746352,0.19620224214011292,0.10157608769830284,0.005872513874080369,0.6542105287099975,6.0439644005275905,0.005872513874080369,0.10157608769830284,-1.2356850843636273,-0.43903817143719953,0.10157608769830284,1.381940746478781,0.7870267798407822,0.005872513874080369,-0.388392317630512,-0.18889877938207092,1.1317712009042973,-0.09094104587744528,0.005872513874080369,-0.09094104587744528,-0.13977468780074367,-0.18889877938207092,0.5193447980380466,0.005872513874080369,-0.4899972174116964,-0.23831786606746352,0.5193447980380466,-0.43903817143719953,0.4739196680085796,0.961063282020524,0.4282542060735226,-0.28803660939734893
3,367
Protein methylation
8
74
2.086648
0.03692
P16403,P10412,P16402,Q9Y3Y2,Q9H7B4,Q9BV86,O60725,Q9Y5B6
Processes and pathways
GO Biological process
msigdb_gobp
191,39,109,44,14,15,86,90
2297,1323,1088,1089,1587,2571,86,463,1876,387,3190,39,2850,109,191,3126,2177,1606,1348,898,590,905,1775,1624,2203,2062,3068,1507,3193,1134,749,2361,2618,2495,2500,2365,1936,2936,1663,1533,1940,2506,1156,2378,2880,1400,1941,2813,676,1164,1165,252,2641,2254,1419,853,1694,15,1295,2269,3280,2408,2953,14,2273,1710,2279,456,1451,2143,44,2293,1455,90
-0.28803660939734893,0.053860976884978005,0.14902186735214557,0.14902186735214557,-0.04239342030431858,-0.388392317630512,1.744890254278231,0.5193447980380466,-0.13977468780074367,0.6094870655900769,-1.0165649980725264,2.9341363071598647,-0.5412682933157936,1.5045080195895706,1.046822951105993,-0.8553842121388305,-0.23831786606746352,-0.04239342030431858,0.053860976884978005,0.24312104666747653,0.4282542060735226,0.24312104666747653,-0.09094104587744528,-0.04239342030431858,-0.23831786606746352,-0.18889877938207092,-0.7494501896778172,0.005872513874080369,-1.0165649980725264,0.14902186735214557,0.3361888423900969,-0.28803660939734893,-0.388392317630512,-0.3380597911426015,-0.3380597911426015,-0.28803660939734893,-0.13977468780074367,-0.5928502525010018,-0.04239342030431858,0.005872513874080369,-0.13977468780074367,-0.3380597911426015,0.14902186735214557,-0.28803660939734893,-0.5412682933157936,0.053860976884978005,-0.13977468780074367,-0.4899972174116964,0.38234507015049096,0.14902186735214557,0.14902186735214557,0.8744716799879915,-0.388392317630512,-0.23831786606746352,0.053860976884978005,0.2897820267826493,-0.04239342030431858,5.081159956656381,0.10157608769830284,-0.23831786606746352,-1.3470325431471153,-0.28803660939734893,-0.5928502525010018,5.364443360547954,-0.23831786606746352,-0.04239342030431858,-0.23831786606746352,0.5645328647779381,0.053860976884978005,-0.18889877938207092,2.7930967970410885,-0.23831786606746352,0.053860976884978005,1.7052535001830216
3,367
Passive transmembrane transporter activity
6
25
2.083786
0.03718
O75964,Q9BVC6,Q9Y696,P21796,Q9C0H2,P45880
Functions
GO Molecular function
msigdb_gomf
33,65,237,100,145,56
2295,584,33,727,1334,2168,2450,2849,100,1347,2777,297,1492,56,2338,475,742,529,1249,1952,953,65,145,980,237
-0.28803660939734893,0.4282542060735226,3.0386401585275027,0.3361888423900969,0.053860976884978005,-0.23831786606746352,-0.3380597911426015,-0.5412682933157936,1.6254733747117993,0.053860976884978005,-0.4899972174116964,0.7429774213920438,0.005872513874080369,2.394640025697565,-0.28803660939734893,0.5193447980380466,0.3361888423900969,0.4739196680085796,0.10157608769830284,-0.13977468780074367,0.24312104666747653,2.0943433015075343,1.2993115136492674,0.24312104666747653,0.9178727874245445
3,367
G1 s dna damage checkpoints
6
41
2.077456
0.037759
P60900,P28074,P20618,P49721,P28072,P61289
Processes and pathways
Reactome Pathways
msigdb_reactome
128,35,192,10,52,283
1319,2436,2437,1579,2567,875,2846,1470,997,1343,192,1229,2458,2179,2041,1895,1771,647,52,35,2193,3177,2197,1011,354,10,1244,2699,128,283,1504,2609,2065,1792,1797,481,1524,2824,2258,638,2426
0.053860976884978005,-0.3380597911426015,-0.3380597911426015,-0.04239342030431858,-0.388392317630512,0.24312104666747653,-0.5412682933157936,0.005872513874080369,0.19620224214011292,0.053860976884978005,1.046822951105993,0.10157608769830284,-0.3380597911426015,-0.23831786606746352,-0.18889877938207092,-0.13977468780074367,-0.09094104587744528,0.38234507015049096,2.431534530000306,3.0039248680970876,-0.23831786606746352,-0.9625354940644615,-0.23831786606746352,0.19620224214011292,0.6542105287099975,6.0439644005275905,0.10157608769830284,-0.43903817143719953,1.381940746478781,0.7870267798407822,0.005872513874080369,-0.388392317630512,-0.18889877938207092,-0.09094104587744528,-0.09094104587744528,0.5193447980380466,0.005872513874080369,-0.4899972174116964,-0.23831786606746352,0.4282542060735226,-0.28803660939734893
3,367
Rac1 gtpase cycle
11
48
2.060408
0.03936
Q9UQB8,Q9Y2I1,Q96F07,Q6IAA8,O75962,Q13459,Q7L576,Q14739,Q9NRY4,P50402,Q14185
Processes and pathways
Reactome Pathways
msigdb_reactome
0,132,269,266,352,330,305,151,156,214,300
3015,2566,579,352,1472,1751,2582,1116,736,3251,1118,214,1014,2784,1125,1787,2482,358,2617,1796,330,3075,300,2497,151,755,3242,1034,1268,266,305,1404,487,2395,269,1053,2995,1976,1697,1561,2740,156,2277,0,869,132,2429,800
-0.6969423099361801,-0.388392317630512,0.4282542060735226,0.6542105287099975,0.005872513874080369,-0.09094104587744528,-0.388392317630512,0.14902186735214557,0.3361888423900969,-1.2356850843636273,0.14902186735214557,0.961063282020524,0.19620224214011292,-0.4899972174116964,0.14902186735214557,-0.09094104587744528,-0.3380597911426015,0.6542105287099975,-0.388392317630512,-0.09094104587744528,0.6987063152944422,-0.7494501896778172,0.7429774213920438,-0.3380597911426015,1.257715066848026,0.3361888423900969,-1.1804567452748522,0.19620224214011292,0.10157608769830284,0.8308572620954069,0.7429774213920438,0.053860976884978005,0.5193447980380466,-0.28803660939734893,0.8308572620954069,0.19620224214011292,-0.6447419635510961,-0.13977468780074367,-0.04239342030431858,0.005872513874080369,-0.43903817143719953,1.257715066848026,-0.23831786606746352,9.674117275578304,0.2897820267826493,1.381940746478781,-0.28803660939734893,0.3361888423900969
3,367
Cerebellar cyst
9
47
2.05475
0.039903
O43505,Q15125,Q14118,Q2M1P5,Q12768,P23786,Q9UBM7,Q6P4I2,P21281
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
70,74,263,205,144,82,54,123,121
1322,986,2020,70,3212,1872,3019,2769,324,3024,121,82,1905,733,1492,2056,1784,1125,1370,144,1134,263,74,1808,205,2240,123,2880,543,2389,1048,2524,952,1285,1687,1053,1692,2262,1423,1845,2270,2131,54,705,2006,803,2565
0.053860976884978005,0.19620224214011292,-0.18889877938207092,2.0177872441211355,-1.070895711677453,-0.13977468780074367,-0.6969423099361801,-0.4899972174116964,0.6987063152944422,-0.6969423099361801,1.422977916752635,1.7843606013886042,-0.13977468780074367,0.3361888423900969,0.005872513874080369,-0.18889877938207092,-0.09094104587744528,0.14902186735214557,0.053860976884978005,1.2993115136492674,0.14902186735214557,0.8308572620954069,1.9792784396533925,-0.09094104587744528,1.004045806677848,-0.23831786606746352,1.422977916752635,-0.5412682933157936,0.4739196680085796,-0.28803660939734893,0.19620224214011292,-0.3380597911426015,0.24312104666747653,0.10157608769830284,-0.04239342030431858,0.19620224214011292,-0.04239342030431858,-0.23831786606746352,0.053860976884978005,-0.09094104587744528,-0.23831786606746352,-0.18889877938207092,2.431534530000306,0.38234507015049096,-0.13977468780074367,0.3361888423900969,-0.3380597911426015
3,367
Abnormality of the skull base
17
68
2.045115
0.040844
P80404,Q9H490,O43505,P49748,Q15125,P21281,Q9UJX6,Q14118,Q2M1P5,Q12768,P23786,Q9UBM7,Q14739,P19022,Q6P4I2,Q9NPL8,Q96L58
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
36,313,70,230,74,121,317,263,205,144,82,54,151,294,123,155,215
983,3016,1322,986,2020,3123,70,3212,1872,3019,2769,2158,1739,1210,324,294,121,2176,82,1112,1905,1492,1911,3358,230,2472,2056,1122,1784,1125,1370,1787,36,665,144,1134,924,263,151,74,1808,205,2240,123,2880,1668,543,2389,1048,2524,952,1285,1687,215,853,1692,2262,1295,1845,2270,313,155,54,2659,705,317,2006,2565
0.19620224214011292,-0.6969423099361801,0.053860976884978005,0.19620224214011292,-0.18889877938207092,-0.8553842121388305,2.0177872441211355,-1.070895711677453,-0.13977468780074367,-0.6969423099361801,-0.4899972174116964,-0.23831786606746352,-0.09094104587744528,0.10157608769830284,0.6987063152944422,0.7429774213920438,1.422977916752635,-0.23831786606746352,1.7843606013886042,0.14902186735214557,-0.13977468780074367,0.005872513874080369,-0.13977468780074367,-5.28006847826639,0.9178727874245445,-0.3380597911426015,-0.18889877938207092,0.14902186735214557,-0.09094104587744528,0.14902186735214557,0.053860976884978005,-0.09094104587744528,2.969090607110795,0.38234507015049096,1.2993115136492674,0.14902186735214557,0.24312104666747653,0.8308572620954069,1.257715066848026,1.9792784396533925,-0.09094104587744528,1.004045806677848,-0.23831786606746352,1.422977916752635,-0.5412682933157936,-0.04239342030431858,0.4739196680085796,-0.28803660939734893,0.19620224214011292,-0.3380597911426015,0.24312104666747653,0.10157608769830284,-0.04239342030431858,0.961063282020524,0.2897820267826493,-0.04239342030431858,-0.23831786606746352,0.10157608769830284,-0.09094104587744528,-0.23831786606746352,0.7429774213920438,1.257715066848026,2.431534530000306,-0.388392317630512,0.38234507015049096,0.7429774213920438,-0.13977468780074367,-0.3380597911426015
3,367
Organic acid transport
9
40
2.040706
0.04128
P30825,O43772,P80404,Q9H2D1,O75915,P23786,P28288,O60831,P11166
Processes and pathways
GO Biological process
msigdb_gobp
212,2,36,105,226,82,428,320,388
2016,3096,2,722,320,1095,226,1880,887,2449,1882,1751,425,2451,890,388,521,82,428,1900,212,589,2188,2978,828,1917,911,2208,36,533,2986,753,1654,755,1271,105,3281,1438,1998,867
-0.18889877938207092,-0.8022645150247569,8.462226464311355,0.3361888423900969,0.6987063152944422,0.14902186735214557,0.9178727874245445,-0.13977468780074367,0.24312104666747653,-0.3380597911426015,-0.13977468780074367,-0.09094104587744528,0.5645328647779381,-0.3380597911426015,0.24312104666747653,0.6094870655900769,0.4739196680085796,1.7843606013886042,0.5645328647779381,-0.13977468780074367,0.961063282020524,0.4282542060735226,-0.23831786606746352,-0.6447419635510961,0.2897820267826493,-0.13977468780074367,0.24312104666747653,-0.23831786606746352,2.969090607110795,0.4739196680085796,-0.6447419635510961,0.3361888423900969,-0.04239342030431858,0.3361888423900969,0.10157608769830284,1.5450050959353323,-1.3470325431471153,0.053860976884978005,-0.13977468780074367,0.2897820267826493
3,367
Long chain fatty acid transport
6
13
2.037336
0.041616
O43772,P14174,P23786,P28288,P11166,P07814
Processes and pathways
GO Biological process
msigdb_gobp
2,521,82,428,388,425
3096,2,887,1882,425,388,521,82,428,589,2188,828,1271
-0.8022645150247569,8.462226464311355,0.24312104666747653,-0.13977468780074367,0.5645328647779381,0.6094870655900769,0.4739196680085796,1.7843606013886042,0.5645328647779381,0.4282542060735226,-0.23831786606746352,0.2897820267826493,0.10157608769830284
3,367
Peptidase complex
12
65
2.037145
0.041635
P60900,O43396,P28074,Q9BRP4,Q9H490,P20618,Q5VYK3,P49721,Q96S52,P28072,P61289,P67812
Localization
GO Cellular component
msigdb_gocc
128,91,35,370,313,192,41,10,175,52,283,241
1319,2436,2437,2567,875,91,2846,2848,2166,818,1343,192,2458,2179,2041,1895,1771,647,52,35,2193,737,2197,1011,354,10,827,1244,1782,3253,2785,2699,2346,128,596,283,1504,2609,2065,241,1928,1792,1797,481,1387,1524,484,2802,41,2634,1548,623,1969,175,2824,2258,370,313,638,2426,457,2150,3012,2755,711
0.053860976884978005,-0.3380597911426015,-0.3380597911426015,-0.388392317630512,0.24312104666747653,1.6654484983059537,-0.5412682933157936,-0.5412682933157936,-0.23831786606746352,0.2897820267826493,0.053860976884978005,1.046822951105993,-0.3380597911426015,-0.23831786606746352,-0.18889877938207092,-0.13977468780074367,-0.09094104587744528,0.38234507015049096,2.431534530000306,3.0039248680970876,-0.23831786606746352,0.3361888423900969,-0.23831786606746352,0.19620224214011292,0.6542105287099975,6.0439644005275905,0.2897820267826493,0.10157608769830284,-0.09094104587744528,-1.2356850843636273,-0.4899972174116964,-0.43903817143719953,-0.28803660939734893,1.381940746478781,0.4282542060735226,0.7870267798407822,0.005872513874080369,-0.388392317630512,-0.18889877938207092,0.8744716799879915,-0.13977468780074367,-0.09094104587744528,-0.09094104587744528,0.5193447980380466,0.053860976884978005,0.005872513874080369,0.5193447980380466,-0.4899972174116964,2.899060884241353,-0.388392317630512,0.005872513874080369,0.4282542060735226,-0.13977468780074367,1.1317712009042973,-0.4899972174116964,-0.23831786606746352,0.6542105287099975,0.7429774213920438,0.4282542060735226,-0.28803660939734893,0.5645328647779381,-0.18889877938207092,-0.6447419635510961,-0.43903817143719953,0.38234507015049096
3,367
Stabilization of p53
6
39
2.028675
0.042491
P60900,P28074,P20618,P49721,P28072,P61289
Processes and pathways
Reactome Pathways
msigdb_reactome
128,35,192,10,52,283
1319,2436,2437,2567,875,2846,1470,997,1343,192,2458,2179,2041,1895,1771,647,52,35,2193,3177,2197,1011,354,10,1244,2699,128,283,1504,2609,2065,1792,1797,481,1524,2824,2258,638,2426
0.053860976884978005,-0.3380597911426015,-0.3380597911426015,-0.388392317630512,0.24312104666747653,-0.5412682933157936,0.005872513874080369,0.19620224214011292,0.053860976884978005,1.046822951105993,-0.3380597911426015,-0.23831786606746352,-0.18889877938207092,-0.13977468780074367,-0.09094104587744528,0.38234507015049096,2.431534530000306,3.0039248680970876,-0.23831786606746352,-0.9625354940644615,-0.23831786606746352,0.19620224214011292,0.6542105287099975,6.0439644005275905,0.10157608769830284,-0.43903817143719953,1.381940746478781,0.7870267798407822,0.005872513874080369,-0.388392317630512,-0.18889877938207092,-0.09094104587744528,-0.09094104587744528,0.5193447980380466,0.005872513874080369,-0.4899972174116964,-0.23831786606746352,0.4282542060735226,-0.28803660939734893
3,367
Abnormality of the mitochondrion
11
88
2.028222
0.042538
O43772,Q4G0N4,Q96CU9,P49748,Q70HW3,O75648,P23786,O43676,Q9P0J0,Q9NPL8,Q9Y2R0
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
2,166,7,230,45,147,82,55,220,155,157
3338,1320,1460,55,3222,2,1874,1465,2025,147,884,3102,3349,1471,3024,2916,1756,817,3313,2585,1000,2173,1605,2322,2323,2687,82,1348,2590,1772,2330,326,2048,2692,1233,1005,1360,1361,230,2864,527,1628,2206,1366,2346,2928,478,603,1648,2799,1809,1530,840,609,166,245,1266,1662,1396,45,3318,2884,1948,488,2391,7,849,1421,553,1290,556,1425,2897,2412,2537,155,1567,1190,220,2657,1998,2905,2428,157,513,3012,2434,1457
-2.2192938988489903,0.053860976884978005,0.005872513874080369,2.394640025697565,-1.1255266262233685,8.462226464311355,-0.13977468780074367,0.005872513874080369,-0.18889877938207092,1.257715066848026,0.24312104666747653,-0.8022645150247569,-2.8994916636965624,0.005872513874080369,-0.6969423099361801,-0.5928502525010018,-0.09094104587744528,0.2897820267826493,-1.7460032195660424,-0.388392317630512,0.19620224214011292,-0.23831786606746352,-0.04239342030431858,-0.28803660939734893,-0.28803660939734893,-0.43903817143719953,1.7843606013886042,0.053860976884978005,-0.388392317630512,-0.09094104587744528,-0.28803660939734893,0.6987063152944422,-0.18889877938207092,-0.43903817143719953,0.10157608769830284,0.19620224214011292,0.053860976884978005,0.053860976884978005,0.9178727874245445,-0.5412682933157936,0.4739196680085796,-0.04239342030431858,-0.23831786606746352,0.053860976884978005,-0.28803660939734893,-0.5928502525010018,0.5193447980380466,0.4282542060735226,-0.04239342030431858,-0.4899972174116964,-0.09094104587744528,0.005872513874080369,0.2897820267826493,0.4282542060735226,1.1739472326847418,0.8744716799879915,0.10157608769830284,-0.04239342030431858,0.053860976884978005,2.7575257190991964,-1.8041620789267372,-0.5412682933157936,-0.13977468780074367,0.5193447980380466,-0.28803660939734893,6.510373398556831,0.2897820267826493,0.053860976884978005,0.4739196680085796,0.10157608769830284,0.4739196680085796,0.053860976884978005,-0.5412682933157936,-0.28803660939734893,-0.3380597911426015,1.257715066848026,0.005872513874080369,0.14902186735214557,0.961063282020524,-0.388392317630512,-0.13977468780074367,-0.5412682933157936,-0.28803660939734893,1.257715066848026,0.5193447980380466,-0.6447419635510961,-0.28803660939734893,0.053860976884978005
3,367
Synthesis of dna
21
83
2.02738
0.042624
P60900,P49721,Q9NRF9,P61289,P63208,P28074,P30260,Q9BRX5,P35250,Q9UJX6,P35251,P28072,P20618,Q99741,Q9UBD5,Q96DE5,Q9UL46,Q9Y248,Q13309,P49720,Q14997
Processes and pathways
Reactome Pathways
msigdb_reactome
128,10,565,283,394,35,391,444,524,317,296,52,192,498,221,96,638,509,232,354,481
1319,2436,2437,2567,875,1586,2846,1755,1479,2174,1343,3027,192,1229,2325,2458,2179,2041,1895,1612,1771,647,52,35,2043,391,2190,1618,2046,2859,2332,524,296,2193,2596,591,2597,2978,2197,1011,1240,1495,354,10,1496,1244,2699,1247,128,283,1504,2609,2065,394,1792,1516,833,1797,232,3241,1934,2933,481,1524,1810,96,2824,2258,498,2264,444,2742,565,221,868,1308,1999,2661,317,638,2426,509,2964
0.053860976884978005,-0.3380597911426015,-0.3380597911426015,-0.388392317630512,0.24312104666747653,-0.04239342030431858,-0.5412682933157936,-0.09094104587744528,0.005872513874080369,-0.23831786606746352,0.053860976884978005,-0.6969423099361801,1.046822951105993,0.10157608769830284,-0.28803660939734893,-0.3380597911426015,-0.23831786606746352,-0.18889877938207092,-0.13977468780074367,-0.04239342030431858,-0.09094104587744528,0.38234507015049096,2.431534530000306,3.0039248680970876,-0.18889877938207092,0.6094870655900769,-0.23831786606746352,-0.04239342030431858,-0.18889877938207092,-0.5412682933157936,-0.28803660939734893,0.4739196680085796,0.7429774213920438,-0.23831786606746352,-0.388392317630512,0.4282542060735226,-0.388392317630512,-0.6447419635510961,-0.23831786606746352,0.19620224214011292,0.10157608769830284,0.005872513874080369,0.6542105287099975,6.0439644005275905,0.005872513874080369,0.10157608769830284,-0.43903817143719953,0.10157608769830284,1.381940746478781,0.7870267798407822,0.005872513874080369,-0.388392317630512,-0.18889877938207092,0.6094870655900769,-0.09094104587744528,0.005872513874080369,0.2897820267826493,-0.09094104587744528,0.9178727874245445,-1.1804567452748522,-0.13977468780074367,-0.5928502525010018,0.5193447980380466,0.005872513874080369,-0.09094104587744528,1.6654484983059537,-0.4899972174116964,-0.23831786606746352,0.5193447980380466,-0.23831786606746352,0.5645328647779381,-0.43903817143719953,0.4739196680085796,0.961063282020524,0.2897820267826493,0.10157608769830284,-0.13977468780074367,-0.388392317630512,0.7429774213920438,0.4282542060735226,-0.28803660939734893,0.5193447980380466,-0.5928502525010018
3,367
Regulation of runx3 expression and activity
6
37
2.025738
0.042792
P60900,P28074,P20618,P49721,P28072,P61289
Processes and pathways
Reactome Pathways
msigdb_reactome
128,35,192,10,52,283
1319,2436,2437,2567,875,2846,1343,192,2458,2179,2041,1895,1771,647,52,35,2193,3177,2197,1011,354,10,1244,2699,128,283,1504,2609,2065,1792,1797,2620,1524,2824,2258,638,2426
0.053860976884978005,-0.3380597911426015,-0.3380597911426015,-0.388392317630512,0.24312104666747653,-0.5412682933157936,0.053860976884978005,1.046822951105993,-0.3380597911426015,-0.23831786606746352,-0.18889877938207092,-0.13977468780074367,-0.09094104587744528,0.38234507015049096,2.431534530000306,3.0039248680970876,-0.23831786606746352,-0.9625354940644615,-0.23831786606746352,0.19620224214011292,0.6542105287099975,6.0439644005275905,0.10157608769830284,-0.43903817143719953,1.381940746478781,0.7870267798407822,0.005872513874080369,-0.388392317630512,-0.18889877938207092,-0.09094104587744528,-0.09094104587744528,-0.388392317630512,0.005872513874080369,-0.4899972174116964,-0.23831786606746352,0.4282542060735226,-0.28803660939734893
3,367
Organic acid transmembrane transport
7
26
2.025406
0.042826
P30825,O43772,Q9H2D1,O75915,P23786,O60831,P11166
Processes and pathways
GO Biological process
msigdb_gobp
212,2,105,226,82,320,388
2,320,1095,226,1880,1751,2451,890,388,82,428,212,589,2188,2978,828,1917,911,533,753,755,105,3281,1438,1998,867
8.462226464311355,0.6987063152944422,0.14902186735214557,0.9178727874245445,-0.13977468780074367,-0.09094104587744528,-0.3380597911426015,0.24312104666747653,0.6094870655900769,1.7843606013886042,0.5645328647779381,0.961063282020524,0.4282542060735226,-0.23831786606746352,-0.6447419635510961,0.2897820267826493,-0.13977468780074367,0.24312104666747653,0.4739196680085796,0.3361888423900969,0.3361888423900969,1.5450050959353323,-1.3470325431471153,0.053860976884978005,-0.13977468780074367,0.2897820267826493
3,367
Adult behavior
6
18
1.998187
0.045696
P80404,P05067,P28289,P50897,O75844,O15118
Processes and pathways
GO Biological process
msigdb_gobp
36,190,102,261,87,125
1086,125,87,2678,190,1599,102,1909,2053,261,1624,36,2379,366,683,3246,1419,2951
0.14902186735214557,1.381940746478781,1.7052535001830216,-0.43903817143719953,1.046822951105993,-0.04239342030431858,1.5853262214974166,-0.13977468780074367,-0.18889877938207092,0.8308572620954069,-0.04239342030431858,2.969090607110795,-0.28803660939734893,0.6542105287099975,0.38234507015049096,-1.1804567452748522,0.053860976884978005,-0.5928502525010018
3,367
Mapk6 mapk4 signaling
6
47
1.985502
0.047089
P60900,P28074,P20618,P49721,P28072,P61289
Processes and pathways
Reactome Pathways
msigdb_reactome
128,35,192,10,52,283
1319,2436,2437,2567,1582,875,2846,2166,1475,1343,192,2689,2458,2179,2041,1895,1771,647,52,35,2193,2197,1011,354,10,1244,2699,128,1125,283,1504,2609,2065,1787,1792,1796,1797,481,1524,1529,3242,2824,2258,1441,2136,638,2426
0.053860976884978005,-0.3380597911426015,-0.3380597911426015,-0.388392317630512,-0.04239342030431858,0.24312104666747653,-0.5412682933157936,-0.23831786606746352,0.005872513874080369,0.053860976884978005,1.046822951105993,-0.43903817143719953,-0.3380597911426015,-0.23831786606746352,-0.18889877938207092,-0.13977468780074367,-0.09094104587744528,0.38234507015049096,2.431534530000306,3.0039248680970876,-0.23831786606746352,-0.23831786606746352,0.19620224214011292,0.6542105287099975,6.0439644005275905,0.10157608769830284,-0.43903817143719953,1.381940746478781,0.14902186735214557,0.7870267798407822,0.005872513874080369,-0.388392317630512,-0.18889877938207092,-0.09094104587744528,-0.09094104587744528,-0.09094104587744528,-0.09094104587744528,0.5193447980380466,0.005872513874080369,0.005872513874080369,-1.1804567452748522,-0.4899972174116964,-0.23831786606746352,0.053860976884978005,-0.18889877938207092,0.4282542060735226,-0.28803660939734893
3,367
Ventricular arrhythmia
9
35
1.98443
0.047208
O43772,Q9BTV4,P49748,Q99996,P23786,P19022,P04899,P50402,P42892
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
2,412,230,83,82,294,322,214,63
2,1328,1465,1744,1471,3190,322,3057,2318,2585,389,3224,3291,294,2323,82,901,2194,1907,63,1361,230,2199,214,3217,1932,1142,616,1409,1168,2525,553,83,412,1567
8.462226464311355,0.053860976884978005,0.005872513874080369,-0.09094104587744528,0.005872513874080369,-1.0165649980725264,0.6987063152944422,-0.7494501896778172,-0.28803660939734893,-0.388392317630512,0.6094870655900769,-1.1255266262233685,-1.4595613570006674,0.7429774213920438,-0.28803660939734893,1.7843606013886042,0.24312104666747653,-0.23831786606746352,-0.13977468780074367,2.132393733047149,0.053860976884978005,0.9178727874245445,-0.23831786606746352,0.961063282020524,-1.070895711677453,-0.13977468780074367,0.14902186735214557,0.4282542060735226,0.053860976884978005,0.14902186735214557,-0.3380597911426015,0.4739196680085796,1.7843606013886042,0.6094870655900769,0.005872513874080369
3,367
Cellular response to hypoxia
6
39
1.983043
0.047363
P60900,P28074,P20618,P49721,P28072,P61289
Processes and pathways
Reactome Pathways
msigdb_reactome
128,35,192,10,52,283
1319,2436,2437,2567,875,2846,1343,192,2458,2179,2041,1895,1771,647,52,35,2193,2197,1011,354,10,1244,2699,128,283,1504,2609,2065,1792,1797,836,481,1524,1805,3196,2824,2258,638,2426
0.053860976884978005,-0.3380597911426015,-0.3380597911426015,-0.388392317630512,0.24312104666747653,-0.5412682933157936,0.053860976884978005,1.046822951105993,-0.3380597911426015,-0.23831786606746352,-0.18889877938207092,-0.13977468780074367,-0.09094104587744528,0.38234507015049096,2.431534530000306,3.0039248680970876,-0.23831786606746352,-0.23831786606746352,0.19620224214011292,0.6542105287099975,6.0439644005275905,0.10157608769830284,-0.43903817143719953,1.381940746478781,0.7870267798407822,0.005872513874080369,-0.388392317630512,-0.18889877938207092,-0.09094104587744528,-0.09094104587744528,0.2897820267826493,0.5193447980380466,0.005872513874080369,-0.09094104587744528,-1.0165649980725264,-0.4899972174116964,-0.23831786606746352,0.4282542060735226,-0.28803660939734893
3,367
Hedgehog off state
16
52
1.980355
0.047664
P60900,P28074,Q8NCM8,P20618,P49721,P48729,Q9UL46,Q9Y496,Q2M1P5,P49720,P68371,P28072,P04350,Q14997,P61289,P63208
Processes and pathways
Reactome Pathways
msigdb_reactome
128,35,543,192,10,653,638,318,205,354,597,52,293,481,283,394
1319,2436,2437,2567,875,2846,293,1222,1338,1343,192,2458,2179,2041,1895,1771,647,52,35,2193,2197,1011,653,354,10,1120,1244,2699,128,283,1504,2609,2065,394,597,1792,1797,1139,3241,1382,481,1524,205,543,1174,2824,2258,2122,3187,638,2426,318
0.053860976884978005,-0.3380597911426015,-0.3380597911426015,-0.388392317630512,0.24312104666747653,-0.5412682933157936,0.7429774213920438,0.10157608769830284,0.053860976884978005,0.053860976884978005,1.046822951105993,-0.3380597911426015,-0.23831786606746352,-0.18889877938207092,-0.13977468780074367,-0.09094104587744528,0.38234507015049096,2.431534530000306,3.0039248680970876,-0.23831786606746352,-0.23831786606746352,0.19620224214011292,0.38234507015049096,0.6542105287099975,6.0439644005275905,0.14902186735214557,0.10157608769830284,-0.43903817143719953,1.381940746478781,0.7870267798407822,0.005872513874080369,-0.388392317630512,-0.18889877938207092,0.6094870655900769,0.4282542060735226,-0.09094104587744528,-0.09094104587744528,0.14902186735214557,-1.1804567452748522,0.053860976884978005,0.5193447980380466,0.005872513874080369,1.004045806677848,0.4739196680085796,0.14902186735214557,-0.4899972174116964,-0.23831786606746352,-0.18889877938207092,-0.9625354940644615,0.4282542060735226,-0.28803660939734893,0.7429774213920438
3,367
Nucleosome assembly
6
34
1.979144
0.0478
P16104,P16403,P10412,P16402,Q9H7B4,P62805
Processes and pathways
GO Biological process
msigdb_gobp
158,191,39,109,14,171
2023,463,3022,889,39,158,109,191,1768,895,2046,1775,2863,1496,658,171,1789,3034,2617,233,3130,1813,1962,1169,1049,1837,1979,1059,629,14,565,3143,2417,703
-0.18889877938207092,0.5193447980380466,-0.6969423099361801,0.24312104666747653,2.9341363071598647,1.2159277397438069,1.5045080195895706,1.046822951105993,-0.09094104587744528,0.24312104666747653,-0.18889877938207092,-0.09094104587744528,-0.5412682933157936,0.005872513874080369,0.38234507015049096,1.1317712009042973,-0.09094104587744528,-0.6969423099361801,-0.388392317630512,0.9178727874245445,-0.8553842121388305,-0.09094104587744528,-0.13977468780074367,0.14902186735214557,0.19620224214011292,-0.09094104587744528,-0.13977468780074367,0.19620224214011292,0.4282542060735226,5.364443360547954,0.4739196680085796,-0.8553842121388305,-0.28803660939734893,0.38234507015049096
3,367
Coated vesicle
20
83
1.979069
0.047808
Q9BVK6,Q12907,P20645,P51572,Q13190,Q9Y282,O15027,Q14108,O43752,Q5VYK3,P04439,P42892,O95070,P05067,Q08379,P53634,Q8N511,Q5VW38,O95487,P01889
Localization
GO Cellular component
msigdb_gocc
558,150,23,393,396,31,275,164,516,41,424,63,423,190,75,328,95,248,466,126
1458,2758,873,2670,275,876,516,2766,1205,2302,1466,886,994,423,996,466,1213,126,1472,424,190,1219,1220,1601,1337,2680,1759,522,23,3176,2192,63,2053,1777,1012,1914,2865,393,2475,1780,328,657,1498,3128,2058,1369,661,1023,920,1926,75,150,1645,396,1138,164,2080,1262,1388,1807,248,41,95,2525,1415,558,1182,2736,2899,2741,972,2278,2834,2548,3168,2552,2553,2662,31,3008,3343,870,1315
0.005872513874080369,-0.4899972174116964,0.24312104666747653,-0.43903817143719953,0.7870267798407822,0.24312104666747653,0.4739196680085796,-0.4899972174116964,0.10157608769830284,-0.28803660939734893,0.005872513874080369,0.24312104666747653,0.19620224214011292,0.5645328647779381,0.19620224214011292,0.5193447980380466,0.10157608769830284,1.381940746478781,0.005872513874080369,0.5645328647779381,1.046822951105993,0.10157608769830284,0.10157608769830284,-0.04239342030431858,0.053860976884978005,-0.43903817143719953,-0.09094104587744528,0.4739196680085796,4.123694916854529,-0.9625354940644615,-0.23831786606746352,2.132393733047149,-0.18889877938207092,-0.09094104587744528,0.19620224214011292,-0.13977468780074367,-0.5412682933157936,0.6094870655900769,-0.3380597911426015,-0.09094104587744528,0.6987063152944422,0.38234507015049096,0.005872513874080369,-0.8553842121388305,-0.18889877938207092,0.053860976884978005,0.38234507015049096,0.19620224214011292,0.24312104666747653,-0.13977468780074367,1.9017911284204507,1.257715066848026,-0.04239342030431858,0.6094870655900769,0.14902186735214557,1.1739472326847418,-0.18889877938207092,0.10157608769830284,0.053860976884978005,-0.09094104587744528,0.8744716799879915,2.899060884241353,1.6654484983059537,-0.3380597911426015,0.053860976884978005,0.4739196680085796,0.14902186735214557,-0.43903817143719953,-0.5412682933157936,-0.43903817143719953,0.24312104666747653,-0.23831786606746352,-0.4899972174116964,-0.3380597911426015,-0.908808220790615,-0.3380597911426015,-0.3380597911426015,-0.388392317630512,3.2104683932450104,-0.6447419635510961,-2.340455914597067,0.2897820267826493,0.10157608769830284
3,367
Metabolism of polyamines
6
38
1.962974
0.049649
P60900,P28074,P20618,P49721,P28072,P61289
Processes and pathways
Reactome Pathways
msigdb_reactome
128,35,192,10,52,283
1319,2436,2437,2567,875,2846,1343,1002,192,2458,2179,2041,1895,1771,647,52,35,2193,2197,1011,354,10,1244,3227,2699,128,283,1504,2609,2065,1792,1797,481,1524,2824,2258,638,2426
0.053860976884978005,-0.3380597911426015,-0.3380597911426015,-0.388392317630512,0.24312104666747653,-0.5412682933157936,0.053860976884978005,0.19620224214011292,1.046822951105993,-0.3380597911426015,-0.23831786606746352,-0.18889877938207092,-0.13977468780074367,-0.09094104587744528,0.38234507015049096,2.431534530000306,3.0039248680970876,-0.23831786606746352,-0.23831786606746352,0.19620224214011292,0.6542105287099975,6.0439644005275905,0.10157608769830284,-1.1255266262233685,-0.43903817143719953,1.381940746478781,0.7870267798407822,0.005872513874080369,-0.388392317630512,-0.18889877938207092,-0.09094104587744528,-0.09094104587744528,0.5193447980380466,0.005872513874080369,-0.4899972174116964,-0.23831786606746352,0.4282542060735226,-0.28803660939734893
3,367
Cortical dysplasia
9
34
1.961087
0.049869
Q6P1N0,Q96N66,Q9NUQ7,Q14139,Q2M389,O43505,Q71SY5,O95721,P07437
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
162,337,130,432,40,70,137,228,324
1869,1577,70,1589,228,324,1217,1764,826,2471,2199,2603,2208,2795,2616,1139,2077,1382,432,40,162,2091,137,1281,2253,1970,337,496,1977,3187,130,794,2139,1194
-0.13977468780074367,-0.04239342030431858,2.0177872441211355,-0.04239342030431858,0.9178727874245445,0.6987063152944422,0.10157608769830284,-0.09094104587744528,0.2897820267826493,-0.3380597911426015,-0.23831786606746352,-0.388392317630512,-0.23831786606746352,-0.4899972174116964,-0.388392317630512,0.14902186735214557,-0.18889877938207092,0.053860976884978005,0.5645328647779381,2.899060884241353,1.2159277397438069,-0.18889877938207092,1.3407193358749927,0.10157608769830284,-0.23831786606746352,-0.13977468780074367,0.6987063152944422,0.5193447980380466,-0.13977468780074367,-0.9625354940644615,1.381940746478781,0.3361888423900969,-0.18889877938207092,0.14902186735214557
3,367
Lysosome
25
51
4.6979
0.000003
P06280,P16278,Q14108,Q93050,Q8NCC3,P10253,P13473,P50897,P10619,O00462,Q15904,P04062,O75503,P11117,P04066,P15586,Q9UI12,Q9Y487,P17900,O15118,Q13510,O14773,P54802,P07602,P20645
Processes and pathways
KEGG Pathways
msigdb_kegg
255,5,6,265,10,269,161,38,40,180,182,56,57,69,319,198,341,358,221,96,101,108,109,113,251
473,180,543,1515,108,96,1454,1318,57,56,319,255,347,113,2649,1214,2617,269,40,69,1039,816,161,1634,198,5,221,251,3228,38,2501,109,1183,2502,2008,1535,1894,101,6,182,10,2602,265,877,1557,641,341,1566,3177,918,358
0.7656032541864601,1.5137692083085525,0.6671297810793578,0.006307474011367515,2.1474158808446684,2.2759315653971224,0.03437193328851483,0.11769676093724667,2.8563508480242543,2.888427682882454,1.0272097103903832,1.2095131214680288,0.9806125526787869,2.110076974296961,-0.6193116841420223,0.17253621044918402,-0.5878385067985065,1.164537106940616,3.227809668601115,2.64250124049558,0.2805565672472788,0.4385882859122563,1.679809873082842,-0.050263952997597124,1.450078310745009,4.4292036485047825,1.3639014130956277,1.231854696356683,-1.4336660463047972,3.2574988008466623,-0.49448594888254555,2.1474158808446684,0.19974671831673846,-0.49448594888254555,-0.2236212584096826,0.006307474011367515,-0.16521660034488708,2.2395519580884713,4.383005400114565,1.5137692083085525,4.301006972369739,-0.5565443734227432,1.187074181061587,0.41257400595833643,0.006307474011367515,0.5920441322650274,1.0039634351651625,0.006307474011367515,-1.2539690378581203,0.38643153062342506,0.9806125526787869
3,367
Anion transport
18
59
4.267695
0.00002
Q9Y277,P21796,P41440,Q15043,P51798,P80404,Q9HC21,P14174,Q9UHG3,Q9C0H2,P08183,P07602,P30825,Q9H2D1,Q9UBX3,P30536,P45880,Q8TB61
Processes and pathways
GO Biological process
msigdb_gobp
166,34,167,263,71,234,107,237,48,80,146,113,85,86,91,124,29,125
2756,961,1454,645,1517,508,1873,545,753,995,1877,113,146,1091,3263,1215,1040,361,237,34,855,124,85,167,29,71,1590,553,2067,2236,234,1186,1223,1226,764,295,2188,263,1433,3206,660,2192,125,470,80,1791,86,1972,1561,107,2207,641,91,48,2483,677,166,1452,3137
-0.7148241860051961,0.3337574021162552,0.03437193328851483,0.5667757956444454,0.006307474011367515,0.7165975954483155,-0.16521660034488708,0.6671297810793578,0.490236763907363,0.30722341578558393,-0.16521660034488708,2.110076974296961,1.7808852976154201,0.25375565145434276,-1.5816442855181783,0.17253621044918402,0.2805565672472788,0.9571562106244959,1.2762487791777117,3.2722740469256966,0.41257400595833643,1.9771403969263128,2.3834885282361222,1.6181799067894833,3.403217513344748,2.6256544201008225,-0.02190402285820215,0.6671297810793578,-0.2530609609086133,-0.34234834725948426,1.2983027806935246,0.19974671831673846,0.17253621044918402,0.17253621044918402,0.490236763907363,1.0963292676298746,-0.31242291199836886,1.187074181061587,0.062290731757696595,-1.3611000187999303,0.5667757956444454,-0.31242291199836886,1.9578570786990497,0.7899351985641869,2.4539090139419626,-0.1074347923116181,2.3657246319376566,-0.19434031752410985,0.006307474011367515,2.165980585241542,-0.31242291199836886,0.5920441322650274,2.312045215706412,3.107165693020846,-0.4637180795900233,0.5667757956444454,1.6388066898289295,0.062290731757696595,-1.1836636419604167
3,367
Vacuolar lumen
21
65
4.224396
0.000024
P06280,P16278,Q14108,Q9UM22,P10253,O00584,P13473,P50897,P10619,Q8NHP8,O00462,P04062,Q9H7Z7,P11117,P04066,P15586,P17900,Q13510,O14773,P54802,P07602
Localization
GO Cellular component
msigdb_gocc
255,5,6,13,269,153,161,38,40,49,180,56,65,69,319,198,221,101,108,109,113
180,625,153,543,108,1454,3182,56,319,255,347,1697,2170,113,2649,648,269,40,69,1757,1812,161,1634,198,5,221,2123,2581,1759,1366,3228,3229,2500,38,2868,1763,2501,1591,109,3013,3042,2008,2353,1333,1706,1224,481,101,6,2809,441,1965,49,1117,2471,2034,1442,877,1730,1503,65,3031,641,13,2823
1.5137692083085525,0.5920441322650274,1.7406977485275759,0.6671297810793578,2.1474158808446684,0.03437193328851483,-1.2894537744189682,2.888427682882454,1.0272097103903832,1.2095131214680288,0.9806125526787869,-0.07877373131780484,-0.31242291199836886,2.110076974296961,-0.6193116841420223,0.5667757956444454,1.164537106940616,3.227809668601115,2.64250124049558,-0.1074347923116181,-0.1362485904097433,1.679809873082842,-0.050263952997597124,1.450078310745009,4.4292036485047825,1.3639014130956277,-0.2826609847711293,-0.5565443734227432,-0.1074347923116181,0.09006522764362623,-1.4336660463047972,-1.4336660463047972,-0.49448594888254555,3.2574988008466623,-0.8120166279085533,-0.1074347923116181,-0.49448594888254555,-0.02190402285820215,2.1474158808446684,-0.977885243317303,-1.011660171259644,-0.2236212584096826,-0.40269627647094874,0.11769676093724667,-0.07877373131780484,0.17253621044918402,0.7656032541864601,2.2395519580884713,4.383005400114565,-0.7470323872777213,0.8382620619356581,-0.19434031752410985,3.045680587864037,0.25375565145434276,-0.4637180795900233,-0.2236212584096826,0.062290731757696595,0.41257400595833643,-0.07877373131780484,0.03437193328851483,2.742374563169135,-0.977885243317303,0.5920441322650274,4.144687074033624,-0.7470323872777213
3,367
Intrinsic component of plasma membrane
32
72
3.895213
0.000098
Q15043,Q8WTV0,Q86UP2,Q9UJS0,P04439,O60637,P02786,P27105,P35613,P05067,P41440,O43657,O00264,Q8N2K0,Q99996,P53985,P16615,Q9Y4G8,Q9NR28,Q99808,Q92542,P30825,Q9H0U3,O96005,Q13641,Q9UIQ6,P10321,O15118,P01889,P51572,P20645,O00560
Localization
GO Cellular component
msigdb_gocc
263,9,397,677,389,24,529,157,286,160,167,53,304,442,184,553,305,59,196,470,218,85,622,220,607,228,229,96,598,238,251,625
680,304,625,2530,1685,782,96,1037,53,2220,24,2576,220,598,529,389,1213,160,995,1877,229,1215,1039,816,1040,305,1042,927,251,157,1217,85,2707,286,2291,167,238,553,792,2236,1186,1223,3046,975,1833,1378,607,263,2411,1433,2021,397,442,2957,1293,9,218,804,1069,470,184,987,1556,622,1308,196,2321,228,677,1623,678,59
0.5413858311413456,1.0503522207387042,0.5920441322650274,-0.525427454868466,-0.07877373131780484,0.46447550012638145,2.2759315653971224,0.2805565672472788,2.9519476787527323,-0.34234834725948426,3.5306255572552185,-0.5565443734227432,1.3639014130956277,0.6171918880980484,0.6919219483408452,0.9099236880488443,0.17253621044918402,1.7001874873242686,0.30722341578558393,-0.16521660034488708,1.3202624041063196,0.17253621044918402,0.2805565672472788,0.4385882859122563,0.2805565672472788,1.0503522207387042,0.2805565672472788,0.3601597156898264,1.231854696356683,1.7204832487252557,0.17253621044918402,2.3834885282361222,-0.6509657620201212,1.1191654406700127,-0.3724389183184647,1.6181799067894833,1.2762487791777117,0.6671297810793578,0.46447550012638145,-0.34234834725948426,0.19974671831673846,0.17253621044918402,-1.011660171259644,0.3337574021162552,-0.1362485904097433,0.09006522764362623,0.6171918880980484,1.187074181061587,-0.4331220969912666,0.062290731757696595,-0.2236212584096826,0.9099236880488443,0.8382620619356581,-0.9109430815275097,0.1451866537146581,4.324586732934785,1.3855822269020739,0.46447550012638145,0.2805565672472788,0.7899351985641869,1.5137692083085525,0.3337574021162552,0.006307474011367515,0.6171918880980484,0.1451866537146581,1.471397176367932,-0.3724389183184647,1.3421283755465698,0.5667757956444454,-0.02190402285820215,0.5667757956444454,2.840232108692598
3,367
Lysosomal lumen
20
36
3.884404
0.000103
P06280,P16278,Q14108,Q9UM22,P10253,O00584,P13473,P50897,P10619,Q8NHP8,O00462,P04062,P11117,P04066,P15586,P17900,Q13510,O14773,P54802,P07602
Localization
GO Cellular component
msigdb_gocc
255,5,6,13,269,153,161,38,40,49,180,56,69,319,198,221,101,108,109,113
180,153,543,108,1454,56,319,255,347,113,2649,648,269,40,69,1757,161,1634,198,5,221,1366,3228,3229,38,109,2008,101,6,441,1965,49,877,1503,641,13
1.5137692083085525,1.7406977485275759,0.6671297810793578,2.1474158808446684,0.03437193328851483,2.888427682882454,1.0272097103903832,1.2095131214680288,0.9806125526787869,2.110076974296961,-0.6193116841420223,0.5667757956444454,1.164537106940616,3.227809668601115,2.64250124049558,-0.1074347923116181,1.679809873082842,-0.050263952997597124,1.450078310745009,4.4292036485047825,1.3639014130956277,0.09006522764362623,-1.4336660463047972,-1.4336660463047972,3.2574988008466623,2.1474158808446684,-0.2236212584096826,2.2395519580884713,4.383005400114565,0.8382620619356581,-0.19434031752410985,3.045680587864037,0.41257400595833643,0.03437193328851483,0.5920441322650274,4.144687074033624
3,367
Corneal opacity
23
58
3.877414
0.000106
P51648,P06280,Q92889,P16278,Q06136,P56589,P10619,P52732,Q9NZC9,P34913,P04062,Q9UBM7,Q16625,O75844,P04066,Q9Y4P3,O43505,O95202,O43933,Q13510,O96028,Q9NVI7,P53701
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
128,255,520,5,142,533,40,421,447,181,56,185,188,68,319,344,87,330,92,101,236,503,363
543,1170,782,87,1084,3094,2573,92,1458,3004,713,2648,68,1875,330,236,1522,56,319,255,1461,40,5,898,650,181,2539,900,2347,128,421,363,2178,533,1472,1707,973,142,2072,2953,101,1103,1652,1901,2775,188,660,3218,1847,520,3026,503,1129,447,185,1743,2042,344
0.6671297810793578,0.19974671831673846,0.46447550012638145,2.3478963961729225,0.25375565145434276,-1.1142272342228774,-0.5565443734227432,2.294021415669942,0.03437193328851483,-0.977885243317303,0.5158731784643796,-0.6193116841420223,2.6926945390869426,-0.16521660034488708,1.0039634351651625,1.2762487791777117,0.006307474011367515,2.888427682882454,1.0272097103903832,1.2095131214680288,0.03437193328851483,3.227809668601115,4.4292036485047825,0.38643153062342506,0.5667757956444454,1.5137692083085525,-0.525427454868466,0.38643153062342506,-0.40269627647094874,1.9384991366690936,0.862258844628111,0.9571562106244959,-0.31242291199836886,0.6919219483408452,0.03437193328851483,-0.07877373131780484,0.3337574021162552,1.820754742930303,-0.2530609609086133,-0.9109430815275097,2.2395519580884713,0.25375565145434276,-0.050263952997597124,-0.16521660034488708,-0.7148241860051961,1.4926272539284748,0.5667757956444454,-1.3972667312364715,-0.1362485904097433,0.7165975954483155,-0.977885243317303,0.7411577066416265,0.25375565145434276,0.8382620619356581,1.5137692083085525,-0.07877373131780484,-0.2236212584096826,1.0039634351651625
3,367
Inorganic molecular entity transmembrane transporter activity
20
57
3.847003
0.00012
Q15043,Q93050,O75964,Q13423,P45880,Q9Y277,P21796,Q9HD20,P16615,P51798,P13073,Q9UI12,Q9C0H2,P56385,O95202,Q9Y487,Q9UBX3,Q6P4Q7,Q9UDW1,P06576
Functions
GO Molecular function
msigdb_gomf
263,265,17,278,29,166,34,165,305,71,73,341,80,214,330,358,91,369,112,250
2756,1454,851,17,330,718,1213,995,250,1697,1810,1091,1756,3263,2060,1040,73,305,927,819,548,2897,34,378,1580,3193,759,970,2498,29,1889,2928,71,2236,2296,214,2502,2237,1186,1223,278,263,3206,369,1604,698,265,80,622,1972,165,91,112,341,166,358,3137
-0.7148241860051961,0.03437193328851483,0.41257400595833643,3.867353512797234,1.0039634351651625,0.5158731784643796,0.17253621044918402,0.30722341578558393,1.231854696356683,-0.07877373131780484,-0.1362485904097433,0.25375565145434276,-0.1074347923116181,-1.5816442855181783,-0.2530609609086133,0.2805565672472788,2.5747617035953736,1.0503522207387042,0.3601597156898264,0.4385882859122563,0.6671297810793578,-0.8447967022235733,3.2722740469256966,0.9335935466195544,-0.02190402285820215,-1.3251632411413339,0.490236763907363,0.3337574021162552,-0.49448594888254555,3.403217513344748,-0.16521660034488708,-0.8777714879158465,2.6256544201008225,-0.34234834725948426,-0.3724389183184647,1.3855822269020739,-0.49448594888254555,-0.34234834725948426,0.19974671831673846,0.17253621044918402,1.1419011221151822,1.187074181061587,-1.3611000187999303,0.9571562106244959,-0.02190402285820215,0.5413858311413456,1.187074181061587,2.4539090139419626,0.6171918880980484,-0.19434031752410985,1.6388066898289295,2.312045215706412,2.1287815015903986,1.0039634351651625,1.6388066898289295,0.9806125526787869,-1.1836636419604167
3,367
Ion transmembrane transporter activity
39
80
3.739587
0.000184
P24539,Q15043,Q93050,O75746,Q9UJS0,O75964,Q13423,P45880,Q6NUK1,P21796,Q9Y277,Q9HD20,P41440,O43808,O43772,O95563,P21281,P53985,P16615,Q9BVC6,P51798,P13073,Q70HW3,Q9UI12,Q9C0H2,P56385,Q99808,P30825,Q9H2D1,O95202,Q9H0U3,Q9Y487,Q9UBX3,Q9HC21,Q6P4Q7,Q9UDW1,P12236,P06576,Q8TB61
Functions
GO Molecular function
msigdb_gomf
378,263,265,508,677,17,278,29,660,34,166,165,167,645,169,545,548,553,305,591,71,73,77,341,80,214,470,85,86,330,622,358,91,107,369,112,361,250,125
2756,961,1454,169,645,508,851,17,330,545,718,1213,995,250,1697,1810,1091,1756,3263,2060,1215,1040,361,73,305,927,819,548,2897,34,378,1580,85,3193,759,970,2498,167,29,1889,2928,71,1590,553,2236,2296,214,2502,2237,1186,1223,278,1839,263,1433,3206,660,2192,369,77,1604,125,698,265,470,591,80,622,86,1972,1561,107,165,91,112,341,677,166,358,3137
-0.7148241860051961,0.3337574021162552,0.03437193328851483,1.5974688426783576,0.5667757956444454,0.7165975954483155,0.41257400595833643,3.867353512797234,1.0039634351651625,0.6671297810793578,0.5158731784643796,0.17253621044918402,0.30722341578558393,1.231854696356683,-0.07877373131780484,-0.1362485904097433,0.25375565145434276,-0.1074347923116181,-1.5816442855181783,-0.2530609609086133,0.17253621044918402,0.2805565672472788,0.9571562106244959,2.5747617035953736,1.0503522207387042,0.3601597156898264,0.4385882859122563,0.6671297810793578,-0.8447967022235733,3.2722740469256966,0.9335935466195544,-0.02190402285820215,2.3834885282361222,-1.3251632411413339,0.490236763907363,0.3337574021162552,-0.49448594888254555,1.6181799067894833,3.403217513344748,-0.16521660034488708,-0.8777714879158465,2.6256544201008225,-0.02190402285820215,0.6671297810793578,-0.34234834725948426,-0.3724389183184647,1.3855822269020739,-0.49448594888254555,-0.34234834725948426,0.19974671831673846,0.17253621044918402,1.1419011221151822,-0.1362485904097433,1.187074181061587,0.062290731757696595,-1.3611000187999303,0.5667757956444454,-0.31242291199836886,0.9571562106244959,2.5060688955133497,-0.02190402285820215,1.9578570786990497,0.5413858311413456,1.187074181061587,0.7899351985641869,0.6422200972561323,2.4539090139419626,0.6171918880980484,2.3657246319376566,-0.19434031752410985,0.006307474011367515,2.165980585241542,1.6388066898289295,2.312045215706412,2.1287815015903986,1.0039634351651625,0.5667757956444454,1.6388066898289295,0.9806125526787869,-1.1836636419604167
3,367
Membrane lipid metabolic process
17
35
3.689853
0.000224
Q9H490,Q99735,P06280,P06865,P16278,P50897,P04066,Q13510,Q8NCC3,Q96G23,Q06136,P07602,Q8NBX0,P04062,Q53H12,O95470,P17900
Processes and pathways
GO Biological process
msigdb_gobp
261,260,255,347,5,38,319,101,10,43,142,113,116,56,440,123,221
448,1317,1572,123,56,319,255,347,113,2649,5,221,2002,756,1218,38,1224,142,1226,101,440,116,10,2312,1969,43,667,260,1069,261,1204,1406,641,704,1979
0.8141544886580385,0.11769676093724667,-0.02190402285820215,1.9771403969263128,2.888427682882454,1.0272097103903832,1.2095131214680288,0.9806125526787869,2.110076974296961,-0.6193116841420223,4.4292036485047825,1.3639014130956277,-0.2236212584096826,0.490236763907363,0.17253621044918402,3.2574988008466623,0.17253621044918402,1.820754742930303,0.17253621044918402,2.2395519580884713,0.8382620619356581,2.072455559506005,4.301006972369739,-0.3724389183184647,-0.19434031752410985,3.1829254312869844,0.5667757956444454,1.2095131214680288,0.2805565672472788,1.2095131214680288,0.19974671831673846,0.09006522764362623,0.5920441322650274,0.5413858311413456,-0.19434031752410985
3,367
Mitochondrial transmembrane transport
17
45
3.602997
0.000315
P24539,Q99595,O95202,P21796,O14925,O43772,P23786,Q9UJZ1,O60830,O75964,P56385,Q9BSK2,P12236,Q9H2D1,Q8IYU8,O75027,P06576
Processes and pathways
GO Biological process
msigdb_gobp
378,37,330,34,262,169,207,317,47,17,214,314,361,86,150,211,250
262,376,169,47,211,2647,508,851,17,2761,330,545,716,1361,995,250,1999,1040,361,34,207,378,1580,759,2928,1181,1590,2296,214,1186,2018,150,1604,2310,1196,37,948,314,86,1972,1561,1307,677,317,1133
1.187074181061587,0.9335935466195544,1.5974688426783576,3.107165693020846,1.3855822269020739,-0.6193116841420223,0.7165975954483155,0.41257400595833643,3.867353512797234,-0.7148241860051961,1.0039634351651625,0.6671297810793578,0.5158731784643796,0.09006522764362623,0.30722341578558393,1.231854696356683,-0.2236212584096826,0.2805565672472788,0.9571562106244959,3.2722740469256966,1.4286699849010147,0.9335935466195544,-0.02190402285820215,0.490236763907363,-0.8777714879158465,0.19974671831673846,-0.02190402285820215,-0.3724389183184647,1.3855822269020739,0.19974671831673846,-0.2236212584096826,1.7608315718187155,-0.02190402285820215,-0.3724389183184647,0.19974671831673846,3.2722740469256966,0.3601597156898264,1.0503522207387042,2.3657246319376566,-0.19434031752410985,0.006307474011367515,0.1451866537146581,0.5667757956444454,1.0503522207387042,0.25375565145434276
3,367
Steroid binding
7
22
3.594627
0.000325
O15118,P21796,Q14108,O15173,P04062,P45880,Q14849
Functions
GO Molecular function
msigdb_gomf
96,34,6,118,56,29,31
304,96,118,1808,56,1213,1810,34,2002,2579,124,1046,1366,29,2008,6,31,1241,2479,400,880,1245
1.0503522207387042,2.2759315653971224,2.0535377021037875,-0.1362485904097433,2.888427682882454,0.17253621044918402,-0.1362485904097433,3.2722740469256966,-0.2236212584096826,-0.5565443734227432,1.9771403969263128,0.2805565672472788,0.09006522764362623,3.403217513344748,-0.2236212584096826,4.383005400114565,3.3454673481684774,0.17253621044918402,-0.4637180795900233,0.9099236880488443,0.41257400595833643,0.17253621044918402
3,367
Intrinsic component of endoplasmic reticulum membrane
20
48
3.566929
0.000361
Q9H490,Q86UP2,Q15629,P57088,P04439,Q15041,Q9BUN8,Q15125,Q9UBM7,O75844,Q8TCT9,Q9Y4P3,Q9Y282,P10321,Q9NQC3,P51572,Q86XL3,O95470,Q99442,Q8TB61
Localization
GO Cellular component
msigdb_gocc
261,397,11,393,389,295,301,177,185,68,201,344,84,229,106,238,111,123,383,125
680,1083,2328,963,68,628,123,598,389,229,2538,1217,1044,238,393,2237,795,1838,1480,295,177,11,2307,905,397,111,484,1547,125,201,2312,1969,431,667,383,3256,301,261,1674,106,2427,1406,704,2521,185,84,344,2113
0.5413858311413456,0.25375565145434276,-0.40269627647094874,0.3337574021162552,2.6926945390869426,0.5920441322650274,1.9771403969263128,0.6171918880980484,0.9099236880488443,1.3202624041063196,-0.525427454868466,0.17253621044918402,0.2805565672472788,1.2762487791777117,0.9099236880488443,-0.34234834725948426,0.46447550012638145,-0.1362485904097433,0.03437193328851483,1.0963292676298746,1.5348236972160396,4.156903668614397,-0.3724389183184647,0.38643153062342506,0.9099236880488443,2.1287815015903986,0.7656032541864601,0.006307474011367515,1.9578570786990497,1.450078310745009,-0.3724389183184647,-0.19434031752410985,0.862258844628111,0.5667757956444454,0.9335935466195544,-1.507173381664675,1.07339179882247,1.2095131214680288,-0.050263952997597124,2.1844760833621826,-0.4331220969912666,0.09006522764362623,0.5413858311413456,-0.49448594888254555,1.5137692083085525,2.401188502744234,1.0039634351651625,-0.2530609609086133
3,367
Anion transmembrane transport
11
35
3.56633
0.000362
Q9Y277,P21796,P51798,Q9HC21,Q9UHG3,P08183,P30825,Q9H2D1,Q9UBX3,P45880,Q8TB61
Processes and pathways
GO Biological process
msigdb_gobp
166,34,71,107,48,146,85,86,91,29,125
645,1517,508,1873,545,995,1877,146,1091,1040,361,34,85,167,29,71,1590,553,2236,1186,1223,764,295,1433,125,86,1972,1561,107,2207,91,48,677,166,1452
0.5667757956444454,0.006307474011367515,0.7165975954483155,-0.16521660034488708,0.6671297810793578,0.30722341578558393,-0.16521660034488708,1.7808852976154201,0.25375565145434276,0.2805565672472788,0.9571562106244959,3.2722740469256966,2.3834885282361222,1.6181799067894833,3.403217513344748,2.6256544201008225,-0.02190402285820215,0.6671297810793578,-0.34234834725948426,0.19974671831673846,0.17253621044918402,0.490236763907363,1.0963292676298746,0.062290731757696595,1.9578570786990497,2.3657246319376566,-0.19434031752410985,0.006307474011367515,2.165980585241542,-0.31242291199836886,2.312045215706412,3.107165693020846,0.5667757956444454,1.6388066898289295,0.062290731757696595
3,367
Intrinsic component of organelle membrane
57
111
3.565737
0.000363
Q9H490,Q16891,O95070,Q9H3K2,O14925,Q96S52,Q86UP2,Q15629,P57088,P04439,Q9BUR5,P56589,Q9Y2R0,Q10471,P13473,Q14739,Q99595,P42892,Q96A33,O43808,Q15041,Q9P035,Q9BUN8,O60830,O95563,Q15125,Q9NX63,Q9UBM7,Q53H12,O75844,Q8TCT9,Q86Y82,Q5XKP0,Q6ZRP7,Q9Y4P3,O43752,Q9Y282,O43505,Q13505,Q86YN1,O15118,P10321,O75880,P01889,O15258,Q9NQC3,Q9HC21,Q86XL3,P51572,Q9Y512,Q15070,Q5SNT2,Q6UXV4,O95470,Q99442,Q8TB61,O76024
Localization
GO Cellular component
msigdb_gocc
261,381,377,672,262,667,397,11,393,389,412,533,26,654,161,289,37,35,431,645,295,704,301,47,545,177,316,185,440,68,201,459,581,457,344,206,84,87,99,484,96,229,597,598,475,106,107,111,238,644,366,382,121,123,383,125,628
680,3092,1083,262,2328,96,475,963,87,206,645,1455,47,2331,68,597,628,2761,752,377,123,545,1361,598,389,229,1040,161,927,1758,2538,1217,1044,3143,35,1181,2235,238,533,393,2237,1186,654,795,99,1838,289,1480,295,366,177,2247,11,767,381,440,2307,382,581,905,121,457,397,111,459,484,1289,2811,2632,1547,1604,125,201,1392,2312,1969,431,667,383,37,948,3256,808,301,412,1555,672,261,1561,2480,107,1674,106,1509,1310,316,2427,1406,704,2521,185,742,1251,1622,84,26,3053,344,1133,644,2113
0.5413858311413456,-1.1142272342228774,0.25375565145434276,1.187074181061587,-0.40269627647094874,2.2759315653971224,0.7656032541864601,0.3337574021162552,2.3478963961729225,1.4286699849010147,0.5667757956444454,0.03437193328851483,3.107165693020846,-0.40269627647094874,2.6926945390869426,0.6171918880980484,0.5920441322650274,-0.7148241860051961,0.490236763907363,0.9335935466195544,1.9771403969263128,0.6671297810793578,0.09006522764362623,0.6171918880980484,0.9099236880488443,1.3202624041063196,0.2805565672472788,1.679809873082842,0.3601597156898264,-0.1074347923116181,-0.525427454868466,0.17253621044918402,0.2805565672472788,-1.2187064928309388,3.2722740469256966,0.19974671831673846,-0.34234834725948426,1.2762487791777117,0.6919219483408452,0.9099236880488443,-0.34234834725948426,0.19974671831673846,0.5667757956444454,0.46447550012638145,2.2759315653971224,-0.1362485904097433,1.1191654406700127,0.03437193328851483,1.0963292676298746,0.9571562106244959,1.5348236972160396,-0.34234834725948426,4.156903668614397,0.490236763907363,0.9335935466195544,0.8382620619356581,-0.3724389183184647,0.9335935466195544,0.6422200972561323,0.38643153062342506,2.0154852262905982,0.8141544886580385,0.9099236880488443,2.1287815015903986,0.8141544886580385,0.7656032541864601,0.1451866537146581,-0.7470323872777213,-0.5878385067985065,0.006307474011367515,-0.02190402285820215,1.9578570786990497,1.450078310745009,0.09006522764362623,-0.3724389183184647,-0.19434031752410985,0.862258844628111,0.5667757956444454,0.9335935466195544,3.2722740469256966,0.3601597156898264,-1.507173381664675,0.46447550012638145,1.07339179882247,0.8861457519054411,0.006307474011367515,0.5667757956444454,1.2095131214680288,0.006307474011367515,-0.4637180795900233,2.165980585241542,-0.050263952997597124,2.1844760833621826,0.03437193328851483,0.1451866537146581,1.0503522207387042,-0.4331220969912666,0.09006522764362623,0.5413858311413456,-0.49448594888254555,1.5137692083085525,0.5158731784643796,0.17253621044918402,-0.02190402285820215,2.401188502744234,3.5306255572552185,-1.011660171259644,1.0039634351651625,0.25375565145434276,0.5920441322650274,-0.2530609609086133
3,367
Cation transmembrane transporter activity
18
53
3.544457
0.000393
Q9HD20,Q15043,Q9Y487,Q93050,O43772,P13073,Q9HC21,Q70HW3,Q9UI12,Q6P4Q7,Q9UDW1,O75964,P56385,P30825,O95202,Q13423,P06576,P16615
Functions
GO Molecular function
msigdb_gomf
165,263,358,265,169,73,107,77,341,369,112,17,214,85,330,278,250,305
169,645,851,17,330,718,1213,995,250,1697,1810,1091,1756,2060,1040,73,305,927,819,548,2897,378,1580,85,3193,759,970,2498,1889,2928,2236,2296,214,2502,2237,1186,278,263,1433,369,77,1604,698,265,470,622,1972,1561,107,165,112,341,358
1.5974688426783576,0.5667757956444454,0.41257400595833643,3.867353512797234,1.0039634351651625,0.5158731784643796,0.17253621044918402,0.30722341578558393,1.231854696356683,-0.07877373131780484,-0.1362485904097433,0.25375565145434276,-0.1074347923116181,-0.2530609609086133,0.2805565672472788,2.5747617035953736,1.0503522207387042,0.3601597156898264,0.4385882859122563,0.6671297810793578,-0.8447967022235733,0.9335935466195544,-0.02190402285820215,2.3834885282361222,-1.3251632411413339,0.490236763907363,0.3337574021162552,-0.49448594888254555,-0.16521660034488708,-0.8777714879158465,-0.34234834725948426,-0.3724389183184647,1.3855822269020739,-0.49448594888254555,-0.34234834725948426,0.19974671831673846,1.1419011221151822,1.187074181061587,0.062290731757696595,0.9571562106244959,2.5060688955133497,-0.02190402285820215,0.5413858311413456,1.187074181061587,0.7899351985641869,0.6171918880980484,-0.19434031752410985,0.006307474011367515,2.165980585241542,1.6388066898289295,2.1287815015903986,1.0039634351651625,0.9806125526787869
3,367
Sphingolipid metabolic process
13
27
3.490856
0.000481
P06280,P06865,P16278,P50897,Q13510,Q8NCC3,Q96G23,Q06136,P07602,P04062,Q53H12,O95470,P17900
Processes and pathways
GO Biological process
msigdb_gobp
255,347,5,38,101,10,43,142,113,56,440,123,221
448,1317,123,56,255,347,113,2649,5,221,2002,756,1218,38,1224,142,1226,101,440,10,43,1069,1204,1406,641,704,1979
0.8141544886580385,0.11769676093724667,1.9771403969263128,2.888427682882454,1.2095131214680288,0.9806125526787869,2.110076974296961,-0.6193116841420223,4.4292036485047825,1.3639014130956277,-0.2236212584096826,0.490236763907363,0.17253621044918402,3.2574988008466623,0.17253621044918402,1.820754742930303,0.17253621044918402,2.2395519580884713,0.8382620619356581,4.301006972369739,3.1829254312869844,0.2805565672472788,0.19974671831673846,0.09006522764362623,0.5920441322650274,0.5413858311413456,-0.19434031752410985
3,367
Azurophil granule
19
68
3.47193
0.000517
P06280,P16278,P10253,P42785,O00584,P27105,P13473,P10619,O00462,O15260,Q9H7Z7,P04066,P15586,Q92542,P17900,P06865,P07602,Q07065,O95721
Localization
GO Cellular component
msigdb_gocc
255,5,269,18,153,157,161,40,180,60,65,319,198,218,221,347,113,120,122
180,625,153,543,60,626,1454,2489,2052,122,3182,319,255,347,1697,2170,113,2649,269,40,1812,1039,161,1634,198,5,221,2123,157,2581,1759,2228,18,2500,2868,1822,1182,1763,2501,1591,3013,3042,2008,2353,1333,1706,1224,120,481,2809,380,769,1965,1342,218,1117,2554,2471,2034,1442,3117,1730,622,65,3031,641,1979,2823
1.5137692083085525,0.5920441322650274,1.7406977485275759,0.6671297810793578,2.775214074894696,0.5920441322650274,0.03437193328851483,-0.49448594888254555,-0.2530609609086133,1.9963496087227715,-1.2894537744189682,1.0272097103903832,1.2095131214680288,0.9806125526787869,-0.07877373131780484,-0.31242291199836886,2.110076974296961,-0.6193116841420223,1.164537106940616,3.227809668601115,-0.1362485904097433,0.2805565672472788,1.679809873082842,-0.050263952997597124,1.450078310745009,4.4292036485047825,1.3639014130956277,-0.2826609847711293,1.7204832487252557,-0.5565443734227432,-0.1074347923116181,-0.34234834725948426,3.8282095648532786,-0.49448594888254555,-0.8120166279085533,-0.1362485904097433,0.19974671831673846,-0.1074347923116181,-0.49448594888254555,-0.02190402285820215,-0.977885243317303,-1.011660171259644,-0.2236212584096826,-0.40269627647094874,0.11769676093724667,-0.07877373131780484,0.17253621044918402,2.0154852262905982,0.7656032541864601,-0.7470323872777213,0.9335935466195544,0.490236763907363,-0.19434031752410985,0.11769676093724667,1.3855822269020739,0.25375565145434276,-0.525427454868466,-0.4637180795900233,-0.2236212584096826,0.062290731757696595,-1.1488380282478365,-0.07877373131780484,0.6171918880980484,2.742374563169135,-0.977885243317303,0.5920441322650274,-0.19434031752410985,-0.7470323872777213
3,367
Mitochondrial transport
34
77
3.440811
0.00058
Q9NS69,P24539,O43615,O14925,P49840,Q9UJS0,O75964,O00170,P07900,P45880,Q14849,P48506,Q5JRX3,Q10713,Q99595,O43772,O60830,Q9UJZ1,Q96EK5,Q53H12,Q9Y276,P23786,O14737,P56385,Q9UBX3,P55786,P04637,P51572,Q9P0J0,Q9Y512,Q15070,P49257,P06576,P30536
Processes and pathways
GO Biological process
msigdb_gobp
0,378,376,262,512,677,17,268,648,29,31,287,658,655,37,169,47,317,444,440,342,207,205,214,91,93,479,238,386,644,366,496,250,124
268,205,262,376,169,47,2331,2647,851,17,2761,2860,2732,2056,716,1361,479,995,250,648,2337,1999,1040,2226,207,378,1580,3240,2290,124,1934,759,2769,29,2928,287,496,512,2234,1181,238,2446,93,2296,214,2739,655,1226,31,366,1189,2018,440,658,660,1488,2811,2632,1196,444,1344,1123,37,2102,1307,1509,0,386,2566,91,677,317,342,2887,1624,644,2755
1.164537106940616,1.4286699849010147,1.187074181061587,0.9335935466195544,1.5974688426783576,3.107165693020846,-0.40269627647094874,-0.6193116841420223,0.41257400595833643,3.867353512797234,-0.7148241860051961,-0.8120166279085533,-0.682802624960496,-0.2530609609086133,0.5158731784643796,0.09006522764362623,0.7656032541864601,0.30722341578558393,1.231854696356683,0.5667757956444454,-0.40269627647094874,-0.2236212584096826,0.2805565672472788,-0.34234834725948426,1.4286699849010147,0.9335935466195544,-0.02190402285820215,-1.4703006768417601,-0.3724389183184647,1.9771403969263128,-0.19434031752410985,0.490236763907363,-0.7148241860051961,3.403217513344748,-0.8777714879158465,1.1191654406700127,0.7411577066416265,0.7165975954483155,-0.34234834725948426,0.19974671831673846,1.2762487791777117,-0.4637180795900233,2.294021415669942,-0.3724389183184647,1.3855822269020739,-0.682802624960496,0.5667757956444454,0.17253621044918402,3.3454673481684774,0.9571562106244959,0.19974671831673846,-0.2236212584096826,0.8382620619356581,0.5667757956444454,0.5667757956444454,0.03437193328851483,-0.7470323872777213,-0.5878385067985065,0.19974671831673846,0.8382620619356581,0.11769676093724667,0.25375565145434276,3.2722740469256966,-0.2530609609086133,0.1451866537146581,0.03437193328851483,4.803828948758111,0.9335935466195544,-0.525427454868466,2.312045215706412,0.5667757956444454,1.0503522207387042,1.0039634351651625,-0.8120166279085533,-0.02190402285820215,0.5920441322650274,-0.682802624960496
3,367
Metal ion homeostasis
26
71
3.424086
0.000617
Q96PU5,Q15043,P30519,P09601,Q8IYU8,P05067,Q96A33,Q9HD20,P09429,Q9UJZ1,Q96TC7,Q15904,Q658P3,P16615,P78417,Q8NE01,O60826,O95202,Q9Y487,O75027,Q8N511,P62942,O00203,Q6P4Q7,P51572,Q16891
Processes and pathways
GO Biological process
msigdb_gobp
521,263,16,21,150,160,431,165,417,317,313,182,189,305,72,335,329,330,358,211,90,97,473,369,238,381
473,1515,1455,2118,329,211,597,1359,628,330,1753,529,2922,1212,1213,160,2649,1810,417,21,817,1418,305,818,927,1141,3140,2538,969,16,3125,2498,999,238,792,2236,2502,1098,97,72,1947,3101,2013,2981,1227,263,2411,182,381,189,369,1011,1490,150,90,335,1604,1292,1196,431,2603,521,313,948,1126,165,317,1623,358,1133,844
0.7656032541864601,0.006307474011367515,0.03437193328851483,-0.2826609847711293,1.0039634351651625,1.3855822269020739,0.6171918880980484,0.09006522764362623,0.5920441322650274,1.0039634351651625,-0.1074347923116181,0.6919219483408452,-0.8777714879158465,0.17253621044918402,0.17253621044918402,1.7001874873242686,-0.6193116841420223,-0.1362485904097433,0.862258844628111,3.613683844728898,0.4385882859122563,0.062290731757696595,1.0503522207387042,0.4385882859122563,0.3601597156898264,0.22681944749468783,-1.2187064928309388,-0.525427454868466,0.3337574021162552,3.9318663108151224,-1.1836636419604167,-0.49448594888254555,0.30722341578558393,1.2762487791777117,0.46447550012638145,-0.34234834725948426,-0.49448594888254555,0.25375565145434276,2.2759315653971224,2.59178502036956,-0.19434031752410985,-1.1142272342228774,-0.2236212584096826,-0.9443136123937819,0.17253621044918402,1.187074181061587,-0.4331220969912666,1.5137692083085525,0.9335935466195544,1.4926272539284748,0.9571562106244959,0.30722341578558393,0.03437193328851483,1.7608315718187155,2.33000339930892,1.0039634351651625,-0.02190402285820215,0.1451866537146581,0.19974671831673846,0.862258844628111,-0.5565443734227432,0.7165975954483155,1.0503522207387042,0.3601597156898264,0.25375565145434276,1.6388066898289295,1.0503522207387042,-0.02190402285820215,0.9806125526787869,0.25375565145434276,0.4385882859122563
3,367
Receptor
13
35
3.368615
0.000755
Q9NS69,Q14739,P24390,Q5KU26,O15118,Q14108,Q8WTV0,Q99720,Q99623,P30825,O15173,P20645,P35613
Functions
Protein Atlas Molecular function
protein_atlas_molecular_function
0,289,2,193,96,6,9,20,282,85,118,251,286
304,2530,1685,96,118,529,1877,720,1929,2828,1880,1039,816,1930,251,2,85,286,422,3046,1378,6,1103,289,1433,193,9,698,282,20,0,705,490,891,2968
1.0503522207387042,-0.525427454868466,-0.07877373131780484,2.2759315653971224,2.0535377021037875,0.6919219483408452,-0.16521660034488708,0.5158731784643796,-0.19434031752410985,-0.7794292005641262,-0.16521660034488708,0.2805565672472788,0.4385882859122563,-0.19434031752410985,1.231854696356683,4.631429349052777,2.3834885282361222,1.1191654406700127,0.862258844628111,-1.011660171259644,0.09006522764362623,4.383005400114565,0.25375565145434276,1.1191654406700127,0.062290731757696595,1.471397176367932,4.324586732934785,0.5413858311413456,1.1419011221151822,3.641045663369028,4.803828948758111,0.5413858311413456,0.7656032541864601,0.41257400595833643,-0.9109430815275097
3,367
SLC superfamily of solute carriers
22
38
3.317568
0.000908
Q15043,O75746,Q9UJS0,Q6NUK1,P41440,O43772,O95563,Q6NT16,Q9BSK2,P53985,Q8IXU6,Q70HW3,Q99808,P30825,Q9H2D1,O95202,Q9H0U3,Q9UBX3,Q9HC21,P12236,Q9NZJ7,Q8TB61
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
263,508,677,660,167,169,545,178,314,553,70,77,470,85,86,330,622,91,107,361,641,125
2328,169,645,508,330,545,995,1091,1215,1040,361,85,167,1590,553,2236,1186,1223,263,1433,3206,178,660,2192,77,70,125,470,314,622,86,1972,1561,107,641,91,677,919
-0.40269627647094874,1.5974688426783576,0.5667757956444454,0.7165975954483155,1.0039634351651625,0.6671297810793578,0.30722341578558393,0.25375565145434276,0.17253621044918402,0.2805565672472788,0.9571562106244959,2.3834885282361222,1.6181799067894833,-0.02190402285820215,0.6671297810793578,-0.34234834725948426,0.19974671831673846,0.17253621044918402,1.187074181061587,0.062290731757696595,-1.3611000187999303,1.5348236972160396,0.5667757956444454,-0.31242291199836886,2.5060688955133497,2.64250124049558,1.9578570786990497,0.7899351985641869,1.0503522207387042,0.6171918880980484,2.3657246319376566,-0.19434031752410985,0.006307474011367515,2.165980585241542,0.5920441322650274,2.312045215706412,0.5667757956444454,0.38643153062342506
3,367
Endoplasmic reticulum golgi intermediate compartment
22
45
3.283164
0.001026
P80303,P24390,O95070,P49755,Q8IUR0,P09429,Q02818,Q15904,Q10472,O15260,Q9Y3B3,Q9Y282,Q15084,Q8N511,P30533,O15258,P07237,P51572,Q13190,Q9BVK6,Q08379,P49257
Localization
GO Cellular component
msigdb_gocc
1,2,377,511,159,417,54,182,308,60,219,84,483,90,225,475,599,238,365,640,497,496
475,60,1037,963,1807,377,599,417,2,2538,225,496,511,1096,238,2835,2501,1591,1,54,497,308,975,365,1479,483,182,1107,159,90,1722,3105,3255,875,1023,640,669,1739,2641,1680,1079,84,219,1082,1684
0.7656032541864601,2.775214074894696,0.2805565672472788,0.3337574021162552,-0.1362485904097433,0.9335935466195544,0.6171918880980484,0.862258844628111,4.631429349052777,-0.525427454868466,1.3421283755465698,0.7411577066416265,0.7165975954483155,0.25375565145434276,1.2762487791777117,-0.7794292005641262,-0.49448594888254555,-0.02190402285820215,4.739957488800412,2.9519476787527323,0.7411577066416265,1.0503522207387042,0.3337574021162552,0.9571562106244959,0.03437193328851483,0.7656032541864601,1.5137692083085525,0.25375565145434276,1.7204832487252557,2.33000339930892,-0.07877373131780484,-1.1142272342228774,-1.507173381664675,0.41257400595833643,0.30722341578558393,0.5920441322650274,0.5667757956444454,-0.07877373131780484,-0.5878385067985065,-0.050263952997597124,0.2805565672472788,2.401188502744234,1.3855822269020739,0.2805565672472788,-0.050263952997597124
3,367
Sphingolipid metabolism
11
25
3.276928
0.001049
P51648,P06280,P16278,Q13510,P10619,Q96G23,Q06136,P07602,P04062,O95470,P17900
Processes and pathways
Reactome Pathways
msigdb_reactome
128,255,5,101,40,43,142,113,56,123,221
680,448,1317,1454,1753,123,56,255,347,113,2649,40,1634,5,221,2002,756,128,142,101,43,3256,1204,641,1979
0.5413858311413456,0.8141544886580385,0.11769676093724667,0.03437193328851483,-0.1074347923116181,1.9771403969263128,2.888427682882454,1.2095131214680288,0.9806125526787869,2.110076974296961,-0.6193116841420223,3.227809668601115,-0.050263952997597124,4.4292036485047825,1.3639014130956277,-0.2236212584096826,0.490236763907363,1.9384991366690936,1.820754742930303,2.2395519580884713,3.1829254312869844,-1.507173381664675,0.19974671831673846,0.5920441322650274,-0.19434031752410985
3,367
Inner mitochondrial membrane protein complex
24
69
3.253827
0.001139
P24539,O14925,P09669,O75964,O43676,Q9BUR5,Q99623,Q8IYU8,P14406,Q99595,O60830,Q9NX63,Q86Y39,P13073,Q9Y276,P56385,Q13505,Q9P0J0,Q9UDW1,P12236,Q6UXV4,P06576,Q16891,Q96CU9
Localization
GO Cellular component
msigdb_gocc
378,262,391,17,19,412,282,150,27,37,47,316,324,73,342,214,99,386,112,361,121,250,381,126
2645,1746,262,19,47,2758,2730,2331,1261,851,17,1876,3202,3054,2827,718,250,1756,391,2060,361,73,27,2701,2896,819,2001,2580,378,1580,3141,3142,3193,2707,759,3143,1889,2928,3265,762,2296,214,99,1840,1539,381,2018,440,581,121,324,150,1604,126,947,37,282,948,412,1307,1310,1129,316,386,112,342,1133,644,920
-0.6193116841420223,-0.1074347923116181,1.187074181061587,3.735568419211056,3.107165693020846,-0.7148241860051961,-0.682802624960496,-0.40269627647094874,0.1451866537146581,0.41257400595833643,3.867353512797234,-0.16521660034488708,-1.3611000187999303,-1.0456406280505959,-0.7794292005641262,0.5158731784643796,1.231854696356683,-0.1074347923116181,0.9099236880488443,-0.2530609609086133,0.9571562106244959,2.5747617035953736,3.4175453651007617,-0.6509657620201212,-0.8447967022235733,0.4385882859122563,-0.2236212584096826,-0.5565443734227432,0.9335935466195544,-0.02190402285820215,-1.2187064928309388,-1.2187064928309388,-1.3251632411413339,-0.6509657620201212,0.490236763907363,-1.2187064928309388,-0.16521660034488708,-0.8777714879158465,-1.5816442855181783,0.490236763907363,-0.3724389183184647,1.3855822269020739,2.2759315653971224,-0.1362485904097433,0.006307474011367515,0.9335935466195544,-0.2236212584096826,0.8382620619356581,0.6422200972561323,2.0154852262905982,1.0272097103903832,1.7608315718187155,-0.02190402285820215,1.9578570786990497,0.3601597156898264,3.2722740469256966,1.1419011221151822,0.3601597156898264,0.8861457519054411,0.1451866537146581,0.1451866537146581,0.25375565145434276,1.0503522207387042,0.9335935466195544,2.1287815015903986,1.0039634351651625,0.25375565145434276,0.5920441322650274,0.38643153062342506
3,367
Arthritis
15
45
3.216623
0.001297
Q14739,P06280,O75844,Q13510,Q14108,P51798,Q8WVQ1,P10321,P14174,O00170,Q96HY6,P04062,P51617,Q9NZ08,P21964
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
289,255,68,101,6,71,103,229,237,268,281,56,307,156,285
268,3181,2759,68,2169,598,1522,56,255,1265,229,2652,237,285,2702,306,1938,1530,307,71,2406,2708,1330,2711,2237,1707,1050,1224,101,6,289,821,1717,1236,103,733,2552,281,700,2157,564,156,1075,3053,1983
1.164537106940616,-1.2894537744189682,-0.7148241860051961,2.6926945390869426,-0.31242291199836886,0.6171918880980484,0.006307474011367515,2.888427682882454,1.2095131214680288,0.1451866537146581,1.3202624041063196,-0.6193116841420223,1.2762487791777117,1.1191654406700127,-0.6509657620201212,1.0503522207387042,-0.19434031752410985,0.006307474011367515,1.0503522207387042,2.6256544201008225,-0.4331220969912666,-0.6509657620201212,0.11769676093724667,-0.6509657620201212,-0.34234834725948426,-0.07877373131780484,0.2805565672472788,0.17253621044918402,2.2395519580884713,4.383005400114565,1.1191654406700127,0.4385882859122563,-0.07877373131780484,0.17253621044918402,2.2029028392455228,0.5158731784643796,-0.525427454868466,1.1419011221151822,0.5413858311413456,-0.2826609847711293,0.6671297810793578,1.7406977485275759,0.2805565672472788,-1.011660171259644,-0.19434031752410985
3,367
Organophosphate ester transport
11
25
3.183484
0.001455
Q9Y255,Q14108,P41440,Q9BZF1,Q8WTV0,Q9HC21,P08183,Q9BSK2,P12236,Q9H2D1,Q8TB61
Processes and pathways
GO Biological process
msigdb_gobp
100,6,167,400,9,107,146,314,361,86,125
645,995,146,1040,361,2002,2579,167,1528,2008,934,1224,6,660,125,9,875,470,314,400,880,86,107,1979,100
0.5667757956444454,0.30722341578558393,1.7808852976154201,0.2805565672472788,0.9571562106244959,-0.2236212584096826,-0.5565443734227432,1.6181799067894833,0.006307474011367515,-0.2236212584096826,0.3601597156898264,0.17253621044918402,4.383005400114565,0.5667757956444454,1.9578570786990497,4.324586732934785,0.41257400595833643,0.7899351985641869,1.0503522207387042,0.9099236880488443,0.41257400595833643,2.3657246319376566,2.165980585241542,-0.19434031752410985,2.2759315653971224
3,367
Abnormal biliary tract morphology
14
25
3.167012
0.00154
Q14739,Q92889,Q10713,Q14108,Q5XKP0,Q9UJW0,Q9Y276,P14174,P07602,P09601,Q9NZJ7,P04062,O43933,P48506
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
289,520,655,6,581,104,342,237,113,21,641,56,92,287
1454,92,1522,56,113,21,237,1634,2925,1094,287,1586,655,690,6,289,581,520,2313,2316,1563,641,104,342,1988
0.03437193328851483,2.294021415669942,0.006307474011367515,2.888427682882454,2.110076974296961,3.613683844728898,1.2762487791777117,-0.050263952997597124,-0.8777714879158465,0.25375565145434276,1.1191654406700127,-0.02190402285820215,0.5667757956444454,0.5413858311413456,4.383005400114565,1.1191654406700127,0.6422200972561323,0.7165975954483155,-0.3724389183184647,-0.3724389183184647,0.006307474011367515,0.5920441322650274,2.2029028392455228,1.0039634351651625,-0.19434031752410985
3,367