term
stringlengths
2
121
overlap
int64
6
281
setsize
int64
7
499
score
float64
1.96
10.6
pval
float64
0
0.05
edge
stringlengths
41
1.97k
type
stringclasses
5 values
subtype
stringclasses
24 values
subtype_key
stringclasses
24 values
edge_idxs
stringlengths
11
1.17k
ann_idxs
stringlengths
19
2.31k
ann_vals
stringlengths
124
9.94k
sig_size
int64
2.2k
3.73k
Mitochondrial substrate/solute carrier [IPR018108]
9
20
2.189495
0.028561
Q9BSK2,P53007,Q6NUK1,Q9NZJ7,Q70HW3,Q9BQT8,Q9H2D1,Q9Y6C9,Q02978
Sequence
InterPro Repeat
interpro_repeat
66,295,37,71,137,369,14,21,185
1258,526,565,890,1907,725,295,446,185,37,137,1612,369,66,14,71,1127,1317,1769,21
-0.029987264639899754,0.5841404732245637,0.5403731266974255,0.23358287308646228,-0.42646435805357247,0.3651554125597333,0.9992186605301409,0.7153554339994393,1.3260434997596127,2.7343969054517516,1.5869821820283412,-0.22805202646620554,0.8464421866784074,2.2590680343749576,3.531016759860818,2.1941483713807117,0.0799038179901403,-0.051977749225718066,-0.31619148521920093,3.1438931605447333
2,719
Mitochondrial carrier domain superfamily [IPR023395]
9
20
2.189495
0.028561
Q9BSK2,P53007,Q6NUK1,Q9NZJ7,Q70HW3,Q9BQT8,Q9H2D1,Q9Y6C9,Q02978
Sequence
InterPro Superfamily
interpro_homologous_superfamily
66,295,37,71,137,369,14,21,185
1258,526,565,890,1907,725,295,446,185,37,137,1612,369,66,14,71,1127,1317,1769,21
-0.029987264639899754,0.5841404732245637,0.5403731266974255,0.23358287308646228,-0.42646435805357247,0.3651554125597333,0.9992186605301409,0.7153554339994393,1.3260434997596127,2.7343969054517516,1.5869821820283412,-0.22805202646620554,0.8464421866784074,2.2590680343749576,3.531016759860818,2.1941483713807117,0.0799038179901403,-0.051977749225718066,-0.31619148521920093,3.1438931605447333
2,719
SLC25 family of mitochondrial transporters
9
20
2.189495
0.028561
Q9BSK2,P53007,Q6NUK1,Q9NZJ7,Q70HW3,Q9BQT8,Q9H2D1,Q9Y6C9,Q02978
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
66,295,37,71,137,369,14,21,185
1258,526,565,890,1907,725,295,446,185,37,137,1612,369,66,14,71,1127,1317,1769,21
-0.029987264639899754,0.5841404732245637,0.5403731266974255,0.23358287308646228,-0.42646435805357247,0.3651554125597333,0.9992186605301409,0.7153554339994393,1.3260434997596127,2.7343969054517516,1.5869821820283412,-0.22805202646620554,0.8464421866784074,2.2590680343749576,3.531016759860818,2.1941483713807117,0.0799038179901403,-0.051977749225718066,-0.31619148521920093,3.1438931605447333
2,719
Anal atresia
6
23
2.180721
0.029204
Q9NX14,P29372,P38398,P53701,Q00653,P21964
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
130,36,105,12,207,57
1626,954,205,2573,57,36,2042,105,1949,1641,12,570,207,1298,878,2121,1204,1307,1033,1348,1698,1587,130
-0.2500804052539133,0.18969433213159956,1.2607374870290988,-1.2239214825682365,2.410450505653213,2.7343969054517516,-0.5147631826654937,1.782394803802914,-0.44853228723201155,-0.2500804052539133,3.724291610215974,0.5403731266974255,1.2607374870290988,-0.051977749225718066,0.25552128409484265,-0.5589399303571009,0.013981381008183963,-0.051977749225718066,0.1457900521946708,-0.07397236668917684,-0.2721130941958622,-0.20602793740355746,1.6304284474013295
2,719
Tetrapyrrole binding
6
17
2.147911
0.031721
Q9H7Z7,P09601,Q16850,P53701,O43169,Q8WUJ1
Functions
GO Molecular function
msigdb_gomf
1,167,43,12,16,55
609,309,16,825,167,1451,174,12,43,1120,55,2247,1997,1,2497,787,2422
0.4965910696538245,0.9555853653924521,3.359057736861852,0.27745581124842733,1.4130733735204561,-0.13998120709098644,1.3913206719265434,3.724291610215974,2.6048899332594044,0.0799038179901403,2.432065641519759,-0.6694630241912155,-0.4706047193760963,6.43359839037501,-1.0017559338441608,0.3213132805171725,-0.868705244209669
2,719
Metapathway biotransformation phase i and ii
7
20
2.126006
0.033503
P78417,Q16850,P34913,O14880,P21964,P07099,Q9Y2Q3
Processes and pathways
WikiPathways
msigdb_wp
6,43,143,81,57,91,132
81,2006,2164,91,2322,1326,1102,57,143,2299,247,6,597,43,1055,471,759,1738,1548,132
2.0858927796510986,-0.49268167695671844,-0.6031351485231468,1.9125353278195374,-0.7579666427366097,-0.07397236668917684,0.0799038179901403,2.410450505653213,1.5217897156162445,-0.7358335434650333,1.1300376796341332,4.709334136817392,0.5184839445253441,2.6048899332594044,0.12383196690835102,0.6716315103115192,0.3432362555482313,-0.2941501139126941,-0.1840081178256045,1.6304284474013295
2,719
Anion transport
16
54
2.124846
0.033599
P53007,Q9Y4C2,Q9Y277,Q6NUK1,O43681,Q9NZJ7,Q9H2D1,Q14728,O00299,Q02978,P45880,P41440,P28288,Q9H0H5,P08195,O60831
Processes and pathways
GO Biological process
msigdb_gobp
295,328,5,37,166,71,14,79,330,185,19,23,302,152,28,29
330,950,166,526,645,29,565,1070,2560,890,1494,2556,891,28,1907,725,1849,545,302,23,19,2243,295,458,727,1857,446,185,2261,553,79,675,938,2688,37,659,1893,695,1086,2095,369,2633,152,14,1062,1388,71,1127,1037,1317,5,328,1769,2214
0.9119384219201073,0.18969433213159956,1.4130733735204561,0.5841404732245637,0.4527941807995276,2.928482575443698,0.5403731266974255,0.10186989473820139,-1.1794458137458657,0.23358287308646228,-0.16199254767822432,-1.1572160679618237,0.23358287308646228,2.9715847052063475,-0.42646435805357247,0.3651554125597333,-0.3823419197946197,0.562258631270515,0.9774037125219504,3.036219049650812,3.22998813104968,-0.6694630241912155,0.9992186605301409,0.6934952597511163,0.3651554125597333,-0.3823419197946197,0.7153554339994393,1.3260434997596127,-0.6915817594107686,0.562258631270515,2.107549554916751,0.4308901360002521,0.21164056141562612,-2.569748375210555,2.7343969054517516,0.4527941807995276,-0.40440090958742253,0.408982336865523,0.10186989473820139,-0.5368492594180034,0.8464421866784074,-1.5805339508292682,1.4783125678161648,3.531016759860818,0.12383196690835102,-0.09597113601877233,2.1941483713807117,0.0799038179901403,0.1457900521946708,-0.051977749225718066,4.944228757073745,0.933763606203496,-0.31619148521920093,-0.6252397432028755
2,719
Microbody membrane
13
24
2.095754
0.036104
Q99614,O00116,Q15067,Q9NR77,O95573,P28288,Q8NBU5,Q7Z434,O43808,P33121,Q96HA9,P12268,P51648
Localization
GO Cellular component
msigdb_gocc
562,475,41,607,429,302,117,52,526,469,25,489,445
475,526,594,2076,429,489,302,469,1601,898,445,1164,41,676,52,117,1143,1509,25,562,1123,2291,607,1519
0.6497641713944446,0.5841404732245637,0.5184839445253441,-0.5368492594180034,0.7372120472317265,0.6278932286014364,0.9774037125219504,0.6716315103115192,-0.22805202646620554,0.23358287308646228,0.7153554339994393,0.035959579209486815,2.6264809912845464,0.4308901360002521,2.4536780695920877,1.6955749871765524,0.05793371881559444,-0.16199254767822432,3.0146767720374004,0.562258631270515,0.0799038179901403,-0.7137052574725953,0.5184839445253441,-0.16199254767822432
2,719
Biological oxidations
8
40
2.090656
0.036559
P78417,Q16850,O43169,O14880,P21964,P07099,O00170,Q9Y2Q3
Processes and pathways
Reactome Pathways
msigdb_reactome
6,43,16,81,57,91,220,132
220,81,2006,16,1705,1156,2136,1669,957,1528,91,2251,1405,1633,2322,1363,1102,57,1193,1852,2710,1714,1532,2299,247,6,597,1079,43,2458,967,1893,623,1085,1997,759,423,629,2447,132
1.1954023203593558,2.0858927796510986,-0.49268167695671844,3.359057736861852,-0.2941501139126941,0.035959579209486815,-0.5810352188562848,-0.2721130941958622,0.18969433213159956,-0.1840081178256045,1.9125353278195374,-0.6915817594107686,-0.1179740763746623,-0.2500804052539133,-0.7579666427366097,-0.09597113601877233,0.0799038179901403,2.410450505653213,0.013981381008183963,-0.3823419197946197,-3.3679484066871597,-0.2941501139126941,-0.1840081178256045,-0.7358335434650333,1.1300376796341332,4.709334136817392,0.5184839445253441,0.10186989473820139,2.6048899332594044,-0.9352078459238161,0.18969433213159956,-0.40440090958742253,0.4965910696538245,0.10186989473820139,-0.4706047193760963,0.3432362555482313,0.7590651135135403,0.4965910696538245,-0.9130352952761474,1.6304284474013295
2,719
Organic anion transmembrane transporter activity
12
24
2.088464
0.036756
P53007,O43808,Q6NUK1,O75746,Q6P1M0,P53985,Q9BQT8,Q9H2D1,Q14728,Q02978,P41440,P08195
Functions
GO Molecular function
msigdb_gomf
295,526,37,565,659,458,369,14,79,185,23,28
950,526,565,890,28,1907,725,23,295,458,185,79,938,37,659,1893,695,1086,369,14,1062,1127,1317,1769
0.18969433213159956,0.5841404732245637,0.5403731266974255,0.23358287308646228,2.9715847052063475,-0.42646435805357247,0.3651554125597333,3.036219049650812,0.9992186605301409,0.6934952597511163,1.3260434997596127,2.107549554916751,0.21164056141562612,2.7343969054517516,0.4527941807995276,-0.40440090958742253,0.408982336865523,0.10186989473820139,0.8464421866784074,3.531016759860818,0.12383196690835102,0.0799038179901403,-0.051977749225718066,-0.31619148521920093
2,719
Positive regulation of transmembrane transport
6
28
2.085929
0.036985
P35754,P78417,Q16539,Q12955,O00483,O75323
Processes and pathways
GO Biological process
msigdb_gobp
0,6,72,199,243,122
243,950,2400,122,1494,891,2648,1016,1564,2240,2356,469,0,1022,2357,798,6,573,935,532,199,72,602,2096,1010,852,923,328
1.1300376796341332,0.18969433213159956,-0.868705244209669,1.652146998033007,-0.16199254767822432,0.23358287308646228,-1.6922841464422418,0.1457900521946708,-0.20602793740355746,-0.6694630241912155,-0.8022473838365787,0.6716315103115192,10.854939911254261,0.1457900521946708,-0.8022473838365787,0.29938647121358847,4.709334136817392,0.5403731266974255,0.21164056141562612,0.5841404732245637,1.2825093816538606,2.1725028920245055,0.5184839445253441,-0.5368492594180034,0.16774416813874526,0.27745581124842733,0.23358287308646228,0.933763606203496
2,719
Carboxylic acid transport
8
26
2.084659
0.0371
P53007,Q9NZJ7,Q9H2D1,Q02978,P28288,P41440,P08195,O60831
Processes and pathways
GO Biological process
msigdb_gobp
295,71,14,185,302,23,28,29
950,29,565,1070,2560,1494,2556,28,1849,302,23,295,458,1857,185,938,659,695,1086,369,14,1062,71,1127,1317,1769
0.18969433213159956,2.928482575443698,0.5403731266974255,0.10186989473820139,-1.1794458137458657,-0.16199254767822432,-1.1572160679618237,2.9715847052063475,-0.3823419197946197,0.9774037125219504,3.036219049650812,0.9992186605301409,0.6934952597511163,-0.3823419197946197,1.3260434997596127,0.21164056141562612,0.4527941807995276,0.408982336865523,0.10186989473820139,0.8464421866784074,3.531016759860818,0.12383196690835102,2.1941483713807117,0.0799038179901403,-0.051977749225718066,-0.31619148521920093
2,719
Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen
11
23
2.075676
0.037924
Q7LBC6,P07237,P09601,O75845,Q16850,Q15800,Q32P28,O95864,P13674,P30519,Q9H6W3
Functions
GO Molecular function
msigdb_gomf
195,133,167,291,43,234,336,46,363,174,450
1559,1809,684,291,46,133,167,363,1363,174,1417,1421,1027,234,43,336,2329,494,195,1343,2383,1148,450
-0.20602793740355746,-0.36028736684757634,0.408982336865523,0.9992186605301409,2.540100867852491,1.6087068455556761,1.4130733735204561,0.8464421866784074,-0.09597113601877233,1.3913206719265434,-0.1179740763746623,-0.1179740763746623,0.1457900521946708,1.1518291881484382,2.6048899332594044,0.9119384219201073,-0.7579666427366097,0.6278932286014364,1.304278048695484,-0.07397236668917684,-0.8243950776997679,0.05793371881559444,0.7153554339994393
2,719
Broad forehead
9
33
2.053101
0.040063
O14936,Q6NUK1,Q9UIG0,P27635,Q8NCH0,P48651,Q96L73,O00170,Q15022
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
164,37,338,293,471,400,89,220,186
220,1282,164,979,1396,954,1564,293,1020,1195,400,1856,1025,1267,715,2340,1752,1298,1338,186,2058,1466,37,1270,878,471,1379,517,89,338,2421,2528,1095
1.1954023203593558,-0.051977749225718066,1.4130733735204561,0.16774416813874526,-0.1179740763746623,0.18969433213159956,-0.20602793740355746,0.9992186605301409,0.1457900521946708,0.013981381008183963,0.7809146468020176,-0.3823419197946197,0.1457900521946708,-0.029987264639899754,0.3870707676702346,-0.7801045809000866,-0.31619148521920093,-0.051977749225718066,-0.07397236668917684,1.3260434997596127,-0.5147631826654937,-0.13998120709098644,2.7343969054517516,-0.029987264639899754,0.25552128409484265,0.6716315103115192,-0.09597113601877233,0.6060186674204603,1.9342151343550622,0.9119384219201073,-0.868705244209669,-1.0683502775229152,0.10186989473820139
2,719
Transferase activity transferring one carbon groups
13
50
2.0514
0.040228
Q96L73,Q9BV44,Q86X55,Q13395,Q6FI81,Q5T280,O60725,P51580,Q8IZ69,P21964,Q15047,Q9HBK9,Q15022
Functions
GO Molecular function
msigdb_gomf
89,228,344,13,77,368,109,247,30,57,343,423,186
1973,979,981,612,109,1527,861,57,774,1674,1497,1018,987,2170,797,444,2278,247,1373,531,1053,904,13,964,186,343,839,368,77,1172,1580,1341,718,344,969,30,970,1994,581,1473,1206,1251,89,1997,1276,228,1480,2642,1481,423
-0.4706047193760963,0.16774416813874526,0.16774416813874526,0.4965910696538245,1.7389908953427926,-0.1840081178256045,0.25552128409484265,2.410450505653213,0.3213132805171725,-0.2721130941958622,-0.16199254767822432,0.1457900521946708,0.16774416813874526,-0.6031351485231468,0.29938647121358847,0.7153554339994393,-0.7137052574725953,1.1300376796341332,-0.09597113601877233,0.5841404732245637,0.12383196690835102,0.23358287308646228,3.552501030946546,0.18969433213159956,1.3260434997596127,0.8901097994094088,0.27745581124842733,0.8464421866784074,2.1292034927296304,0.035959579209486815,-0.20602793740355746,-0.07397236668917684,0.3870707676702346,0.8901097994094088,0.18969433213159956,2.906927719016569,0.18969433213159956,-0.4706047193760963,0.5403731266974255,-0.13998120709098644,0.013981381008183963,-0.008000894112593934,1.9342151343550622,-0.4706047193760963,-0.029987264639899754,1.17361739768586,-0.13998120709098644,-1.6475656902381024,-0.13998120709098644,0.7590651135135403
2,719
Factors involved in megakaryocyte development and platelet production
16
38
2.049932
0.040371
P04637,Q99661,Q9NSK0,P47756,P45973,O95140,Q92769,Q9BW19,Q00535,Q02241,Q07866,Q92667,Q9H0H5,P47755,Q9H0B6,O00139
Processes and pathways
Reactome Pathways
msigdb_reactome
442,518,34,478,323,352,662,436,573,616,18,146,152,652,384,592
592,1809,352,1358,1072,442,1404,985,1448,1409,1981,323,652,478,2200,1458,2300,800,1418,573,616,18,905,1199,837,146,662,2123,1348,518,1253,1869,436,384,152,2435,34,701
0.5184839445253441,-0.36028736684757634,0.868277725439512,-0.09597113601877233,0.10186989473820139,0.7153554339994393,-0.1179740763746623,0.16774416813874526,-0.13998120709098644,-0.1179740763746623,-0.4706047193760963,0.933763606203496,0.4527941807995276,0.6497641713944446,-0.6252397432028755,-0.13998120709098644,-0.7358335434650333,0.29938647121358847,-0.1179740763746623,0.5403731266974255,0.4965910696538245,3.273020993047377,0.23358287308646228,0.013981381008183963,0.27745581124842733,1.5217897156162445,0.4527941807995276,-0.5589399303571009,-0.07397236668917684,0.6060186674204603,-0.008000894112593934,-0.3823419197946197,0.7372120472317265,0.824603169692831,1.4783125678161648,-0.8908677705657063,2.777545039528239,0.408982336865523
2,719
Phosphatase activity
11
46
2.014449
0.043962
Q9NQ88,Q9H0C8,P34913,A6NDG6,Q9NPH0,Q9BRJ7,Q96HS1,P10586,Q5TFE4,P18031,Q9NTJ5
Functions
GO Molecular function
msigdb_gomf
102,204,143,230,50,54,53,246,282,61,129
230,743,1594,1669,1042,246,2680,61,1261,1530,143,2279,1604,2148,2339,377,286,1267,1239,801,935,618,2553,1828,555,1506,658,282,1344,1273,1929,53,1693,625,54,204,1895,1434,1481,762,50,102,129,1620,816,1352
1.1518291881484382,0.3432362555482313,-0.22805202646620554,-0.2721130941958622,0.12383196690835102,1.1300376796341332,-2.2985707787397356,2.3023339178029567,-0.029987264639899754,-0.1840081178256045,1.5217897156162445,-0.7137052574725953,-0.22805202646620554,-0.5810352188562848,-0.7801045809000866,0.824603169692831,1.021030222259417,-0.029987264639899754,-0.008000894112593934,0.29938647121358847,0.21164056141562612,0.4965910696538245,-1.1349916724382347,-0.36028736684757634,0.562258631270515,-0.16199254767822432,0.4527941807995276,1.042838410457467,-0.07397236668917684,-0.029987264639899754,-0.42646435805357247,2.4536780695920877,-0.2721130941958622,0.4965910696538245,2.4536780695920877,1.2825093816538606,-0.40440090958742253,-0.1179740763746623,-0.13998120709098644,0.3432362555482313,2.4968948352339932,1.8257867927639582,1.6304284474013295,-0.22805202646620554,0.29938647121358847,-0.07397236668917684
2,719
Slc transporter disorders
11
30
1.987396
0.046879
P49790,P37198,Q9NRG9,P53985,Q99567,Q8TEM1,Q9BTX1,Q8NFH5,P08195,P52948,Q9UKX7
Processes and pathways
Reactome Pathways
msigdb_reactome
124,354,269,458,156,250,347,123,28,312,131
771,28,2296,1408,1139,775,354,124,490,312,458,777,728,803,2527,659,1427,1271,2205,123,250,1381,1474,1475,156,347,1034,2446,269,131
0.3213132805171725,2.9715847052063475,-0.7358335434650333,-0.1179740763746623,0.05793371881559444,0.3213132805171725,0.868277725439512,1.6304284474013295,0.6278932286014364,0.9555853653924521,0.6934952597511163,0.3213132805171725,0.3651554125597333,0.29938647121358847,-1.0683502775229152,0.4527941807995276,-0.1179740763746623,-0.029987264639899754,-0.6252397432028755,1.652146998033007,1.1300376796341332,-0.09597113601877233,-0.13998120709098644,-0.13998120709098644,1.4565693103741955,0.8901097994094088,0.1457900521946708,-0.9130352952761474,1.0864447167833198,1.6304284474013295
2,719
Cargo receptor activity
6
8
2.059069
0.039488
Q8WTV0,Q07954,O15260,P02786,Q14108,Q5KU26
Functions
GO Molecular function
msigdb_gomf
40,105,103,77,302,116
103,77,105,394,302,753,116,40
1.7410751440437462,2.083788017834852,1.7410751440437462,0.612754461305487,0.7830549684950545,0.2364824390371457,1.634316902127457,2.8273344230678177
2,719
Anion transport
27
54
4.097076
0.000042
Q15043,O75915,Q9UJS0,P51790,Q9NZJ7,P21796,Q9H2D1,P12236,Q9Y277,Q96QD8,P45880,Q9UHG3,Q9UBX3,P07602,Q6NUK1,Q9Y4C2,Q9C0H2,Q9HD26,Q9BQT8,P12235,Q08722,P08183,P05141,Q8TB61,Q9H9B4,O60831,Q9Y619
Processes and pathways
GO Biological process
msigdb_gobp
386,383,262,261,265,12,13,143,146,147,22,28,38,168,299,47,49,308,311,186,188,322,327,78,334,95,125
2067,2040,389,600,979,95,449,383,2122,327,1650,168,322,806,186,143,1355,12,740,1385,22,261,781,823,604,471,566,677,188,1743,759,386,864,2542,299,2337,78,646,147,709,311,49,594,13,334,308,265,38,28,262,146,47,125,2608
-0.587106244130671,-0.5703108638932032,0.8647862588625002,0.49819048944279026,0.08863020155351369,2.22575796347679,0.736834876495512,0.8774087768247075,-0.620867881511793,1.0631453851685053,-0.3409219722772057,1.69263057727874,1.087415425314427,0.2478813025768698,1.605631086088607,1.8832934520415403,-0.1677772467277911,3.451175716066335,0.3186519434677123,-0.18327357472878134,3.253054371219224,1.289267000376432,0.2763076509973368,0.23360837776605786,0.49819048944279026,0.6978221404482146,0.5387428051993683,0.402300331182603,1.605631086088607,-0.38919874485326694,0.30457623372576403,0.8774087768247075,0.1905477242530135,-1.0635076502293486,1.1595533384376537,-0.7932038385838693,2.379619278698563,0.44361639063605623,1.8728793126258834,0.3606474828614861,1.1356182999373312,2.763729779838205,0.5117436144293259,3.4433864453496845,1.038761445699194,1.147599572470142,1.2776071666564428,2.911763976530236,3.0892351012046553,1.289267000376432,1.8832934520415403,2.7725504193892325,1.965878763574573,-1.213975141317416
2,719
Sphingolipid metabolism
14
25
3.765996
0.000166
Q06136,Q13510,O15269,P06280,P17900,P07602,P04062,Q96G23,P16278,P06865,Q16739,P10619,O95470,P51648
Processes and pathways
Reactome Pathways
msigdb_reactome
65,35,260,226,135,168,71,45,206,177,83,89,93,64
908,260,1070,389,981,93,71,226,177,168,1818,89,206,135,2251,672,64,65,35,83,45,2063,1014,265,1404
0.1471191126541989,1.289267000376432,0.014556932935040613,0.8647862588625002,0.08863020155351369,2.245234151230295,2.5107215183813394,1.4271945957883734,1.6275159466122078,1.69263057727874,-0.43794554085718024,2.2936167157241867,1.5060072044287904,1.9247467241533158,-0.7062882632563935,0.402300331182603,2.5750940135788953,2.5750940135788953,2.971565848245718,2.3511047492659554,2.798926517414969,-0.5703108638932032,0.07390195373379957,1.2776071666564428,-0.18327357472878134
2,719
Inorganic molecular entity transmembrane transporter activity
29
62
3.751943
0.000175
Q15043,P51790,Q9Y487,O43681,P21796,Q9UDW1,Q93050,Q9Y277,Q96QD8,P45880,P13073,O75964,Q9UBX3,P05023,P20020,Q96ES6,Q9C0H2,P00403,P12235,O95202,P05141,Q99797,P56385,Q9Y5K8,P61421,P24539,Q7KZN9,Q9HD20,Q6P4Q7
Functions
GO Molecular function
msigdb_gomf
386,261,395,389,12,14,401,146,147,22,286,34,38,295,170,300,49,305,186,326,327,201,336,341,348,98,364,120,122
2067,389,804,34,326,305,295,327,751,2071,2103,806,1006,1291,186,286,547,170,504,877,2404,12,98,2476,807,794,515,2182,22,408,2520,261,471,852,336,348,1715,566,1366,677,1304,386,2542,122,364,989,2454,401,844,300,147,709,201,49,120,38,14,973,146,395,341,2608
-0.587106244130671,0.8647862588625002,0.2478813025768698,2.971565848245718,1.0631453851685053,1.147599572470142,1.1714797320050525,1.0631453851685053,0.30457623372576403,-0.587106244130671,-0.6039584463179856,0.2478813025768698,0.07390195373379957,-0.13692690238543065,1.605631086088607,1.2189142308211247,0.5656005771908399,1.6710149037139495,0.632136528586786,0.17611273471205496,-0.8638509468356808,3.451175716066335,2.215993204297903,-0.9536034576855446,0.2478813025768698,0.26211431465637414,0.6188981125431084,-0.6548601180580003,3.253054371219224,0.826732699034428,-1.0265997707300218,1.289267000376432,0.6978221404482146,0.20494183108481331,1.0265264066984594,0.9896472724402028,-0.37305474027032975,0.5387428051993683,-0.1677772467277911,0.402300331182603,-0.13692690238543065,0.8774087768247075,-1.0635076502293486,1.98632596881489,0.9525040135933169,0.08863020155351369,-0.9175064966386184,0.8521328477933847,0.2192953010576298,1.1595533384376537,1.8728793126258834,0.3606474828614861,1.5615865779228295,2.763729779838205,2.0066948267496136,2.911763976530236,3.427774762153474,0.10331578012873843,1.8832934520415403,0.8647862588625002,1.0265264066984594,-1.213975141317416
2,719
Sphingolipid metabolic process
15
28
3.750981
0.000176
Q06136,Q13510,Q9NZ01,O15269,P06280,P17900,P07602,Q9NZJ7,P04062,Q96G23,P16278,P06865,Q16739,P50897,O95470
Processes and pathways
GO Biological process
msigdb_gobp
65,35,230,260,226,135,168,265,71,45,206,177,83,24,93
260,1070,563,93,71,226,177,168,1818,206,135,2251,672,589,24,65,1391,35,83,1393,1148,45,679,1014,230,265,302,1404
1.289267000376432,0.014556932935040613,0.5387428051993683,2.245234151230295,2.5107215183813394,1.4271945957883734,1.6275159466122078,1.69263057727874,-0.43794554085718024,1.5060072044287904,1.9247467241533158,-0.7062882632563935,0.402300331182603,0.5117436144293259,3.1471316821409943,2.5750940135788953,-0.18327357472878134,2.971565848245718,2.3511047492659554,-0.18327357472878134,-0.030413098045804464,2.798926517414969,0.402300331182603,0.07390195373379957,1.4271945957883734,1.2776071666564428,1.1595533384376537,-0.18327357472878134
2,719
Intrinsic component of endoplasmic reticulum membrane
27
47
3.746708
0.000179
Q9Y282,P51572,Q969X5,P27824,O76024,P57088,Q9P035,O75298,P10321,Q86XL3,Q03518,Q86YN1,Q9NPA0,Q8TB61,Q5J8M3,Q9HCU5,O75844,Q8TCT8,Q96A33,O95470,Q15629,Q9NZ01,Q12981,Q9NQC3,Q8TCT9,Q9BUN8,O43292
Localization
GO Cellular component
msigdb_gocc
2,385,392,522,167,297,302,303,312,58,447,75,463,78,337,476,82,212,213,93,96,230,228,109,498,116,248
908,248,1481,303,82,167,93,1457,312,2367,522,2349,385,297,1715,447,228,1528,839,96,337,798,58,75,1862,78,212,498,688,1698,392,213,1281,1282,2063,116,541,476,463,109,230,302,1177,1672,2,803,831
0.1471191126541989,1.3471792062317862,-0.23005094416154934,1.147599572470142,2.3511047492659554,1.69263057727874,2.245234151230295,-0.2144101059765268,1.123609385664931,-0.8284013522129561,0.6056254989038173,-0.8107713240707701,0.8774087768247075,1.1714797320050525,-0.37305474027032975,0.7497737515679389,1.4271945957883734,-0.2614793772811411,0.2192953010576298,2.22575796347679,1.0265264066984594,0.26211431465637414,2.611536121609732,2.4455700591414438,-0.4543006169521521,2.379619278698563,1.483609806203434,0.6453409341751739,0.38845375763582707,-0.3569626006240997,0.8647862588625002,1.483609806203434,-0.12157226993528147,-0.12157226993528147,-0.5703108638932032,2.087399401896311,0.5923184989479339,0.6978221404482146,0.7108592467728196,2.157026937488641,1.4271945957883734,1.1595533384376537,-0.04549245437206825,-0.3409219722772057,4.013195205240466,0.26211431465637414,0.23360837776605786
2,719
transporter
24
55
3.736962
0.000186
Q8TEX9,Q99595,Q9HD45,Q15070,O43681,P62072,Q9H2D1,O15397,O60830,O00410,Q8N1F7,O75694,O60518,O43772,O00505,O60684,P57740,Q92973,P52294,Q14974,Q8NFH4,Q9Y619,O43615,Q9NR77
Functions
Panther Protein class
panther_protein_class
133,6,137,141,389,10,13,266,19,402,287,161,438,437,325,455,472,90,220,349,350,125,379,253
402,325,1760,2474,1793,266,379,389,437,438,455,19,161,779,1504,2126,1385,753,2078,1606,220,1200,781,823,604,835,472,1715,10,1145,349,141,1436,2542,1010,287,350,1192,133,90,1026,1280,1563,6,679,2426,585,13,499,137,253,1031,1087,546,125
0.8394483821163174,1.0631453851685053,-0.4053949717396913,-0.9536034576855446,-0.421643782078971,1.2659212488513751,0.8900005618991303,0.8647862588625002,0.7626802321711698,0.7626802321711698,0.723863433268658,3.317234140715181,1.7355981785016048,0.2763076509973368,-0.24574059272730153,-0.620867881511793,-0.18327357472878134,0.30457623372576403,-0.587106244130671,-0.3089938532666943,1.4498335257671533,-0.07578689853775272,0.2763076509973368,0.23360837776605786,0.49819048944279026,0.2192953010576298,0.6978221404482146,-0.37305474027032975,3.4899576845407503,-0.030413098045804464,0.9896472724402028,1.9040605759318283,-0.19881775585569805,-1.0635076502293486,0.07390195373379957,1.2189142308211247,0.9896472724402028,-0.0606169582349026,1.9350596419712964,2.2646396892872667,0.05913077172037472,-0.12157226993528147,-0.2772676267666931,3.7466882849921066,0.402300331182603,-0.8816714825203786,0.5252609862464442,3.4433864453496845,0.6453409341751739,1.9247467241533158,1.3125089094881686,0.05913077172037472,0.014556932935040613,0.5789769223558233,1.965878763574573
2,719
Cation transmembrane transporter activity
31
57
3.724043
0.000196
Q15043,P36543,P51790,Q9Y487,Q9UDW1,Q93050,Q96QD8,P13073,P47985,O75964,P05023,P16615,P20020,Q96ES6,P00403,O43772,P12235,O95202,P05141,Q70HW3,Q9H9B4,P56385,Q9Y5K8,P55011,P61421,P24539,P20674,Q7KZN9,Q9HD20,Q6P4Q7,Q9Y619
Functions
GO Molecular function
msigdb_gomf
386,515,261,395,14,401,147,286,408,34,295,547,170,300,305,437,186,326,327,76,334,336,341,471,348,98,504,364,120,122,125
437,600,804,34,326,305,295,327,751,2071,2103,806,1006,1291,186,286,547,170,504,877,2404,98,2476,807,794,515,2182,408,2520,261,471,852,336,348,1715,566,1366,1304,386,864,122,76,364,989,2454,401,844,300,646,147,334,120,14,973,395,341,125
0.7626802321711698,0.49819048944279026,0.2478813025768698,2.971565848245718,1.0631453851685053,1.147599572470142,1.1714797320050525,1.0631453851685053,0.30457623372576403,-0.587106244130671,-0.6039584463179856,0.2478813025768698,0.07390195373379957,-0.13692690238543065,1.605631086088607,1.2189142308211247,0.5656005771908399,1.6710149037139495,0.632136528586786,0.17611273471205496,-0.8638509468356808,2.215993204297903,-0.9536034576855446,0.2478813025768698,0.26211431465637414,0.6188981125431084,-0.6548601180580003,0.826732699034428,-1.0265997707300218,1.289267000376432,0.6978221404482146,0.20494183108481331,1.0265264066984594,0.9896472724402028,-0.37305474027032975,0.5387428051993683,-0.1677772467277911,-0.13692690238543065,0.8774087768247075,0.1905477242530135,1.98632596881489,2.436197942025277,0.9525040135933169,0.08863020155351369,-0.9175064966386184,0.8521328477933847,0.2192953010576298,1.1595533384376537,0.44361639063605623,1.8728793126258834,1.038761445699194,2.0066948267496136,3.427774762153474,0.10331578012873843,0.8647862588625002,1.0265264066984594,1.965878763574573
2,719
Lysosome
27
46
3.694843
0.00022
O14773,P17900,Q9Y487,P54802,Q8NHS3,O43681,Q9NZJ7,Q93050,O15118,P11117,P50897,Q13510,P07602,P06865,P61916,Q14108,P04062,P16278,P10619,P61421,P09497,P06280,O75503,Q99523,Q15904,Q9UMR5,P10253
Processes and pathways
KEGG Pathways
msigdb_kegg
134,135,395,264,270,389,265,401,273,275,24,35,168,177,446,193,71,206,89,348,353,226,231,365,240,121,380
2147,1760,134,273,389,2544,231,71,1034,226,177,168,1818,955,353,380,89,275,1292,956,822,206,135,467,2636,24,1244,264,348,446,2355,1742,35,193,240,1148,270,401,365,1232,265,973,2361,121,668,395
-0.6378349653375106,-0.4053949717396913,1.9247467241533158,1.2542091223510612,0.8647862588625002,-1.082065937615682,1.404457491582026,2.5107215183813394,0.04431638803769443,1.4271945957883734,1.6275159466122078,1.69263057727874,-0.43794554085718024,0.10331578012873843,0.9772957319876318,0.8900005618991303,2.2936167157241867,1.2424706616319041,-0.13692690238543065,0.10331578012873843,0.23360837776605786,1.5060072044287904,1.9247467241533158,0.6978221404482146,-1.3299369864356707,3.1471316821409943,-0.10626425831084813,1.2776071666564428,0.9896472724402028,0.7497737515679389,-0.8107713240707701,-0.38919874485326694,2.971565848245718,1.5836549017230799,1.3701657615426401,-0.030413098045804464,1.2659212488513751,0.8521328477933847,0.9525040135933169,-0.09100256702323781,1.2776071666564428,0.10331578012873843,-0.8107713240707701,2.0066948267496136,0.41610948501277006,0.8647862588625002
2,719
Lysosomal lumen
20
31
3.635023
0.000278
O14773,P17900,P54802,Q9NZJ7,P38435,P11117,P50897,Q13510,P07602,P06865,Q14108,P04062,Q9UM22,P16278,Q8NHP8,P10619,P06280,Q8IV08,Q9UMR5,P10253
Localization
GO Cellular component
msigdb_gocc
134,135,264,265,139,275,24,35,168,177,193,71,205,206,216,89,226,232,121,380
658,134,389,71,1034,226,177,168,1818,1133,380,89,275,1240,822,206,135,139,2636,24,264,446,35,193,232,2293,216,1104,265,205,121
0.41610948501277006,1.9247467241533158,0.8647862588625002,2.5107215183813394,0.04431638803769443,1.4271945957883734,1.6275159466122078,1.69263057727874,-0.43794554085718024,-0.030413098045804464,0.8900005618991303,2.2936167157241867,1.2424706616319041,-0.10626425831084813,0.23360837776605786,1.5060072044287904,1.9247467241533158,1.9040605759318283,-1.3299369864356707,3.1471316821409943,1.2776071666564428,0.7497737515679389,2.971565848245718,1.5836549017230799,1.404457491582026,-0.7408719578287188,1.4723751800675877,-0.00038868636313022414,1.2776071666564428,1.5394252878937733,2.0066948267496136
2,719
Anion transmembrane transport
21
34
3.615882
0.000299
O75915,Q9UJS0,P51790,P21796,Q9H2D1,P12236,Q9Y277,P45880,Q9UHG3,Q9UBX3,Q9Y4C2,Q9HD26,Q9BQT8,P12235,P08183,O75746,P05141,Q8TB61,Q9H9B4,O60831,Q9Y619
Processes and pathways
GO Biological process
msigdb_gobp
383,262,261,12,13,143,146,22,28,38,47,308,311,186,322,449,327,78,334,95,125
600,95,449,383,327,1650,322,806,186,143,12,1385,22,261,781,823,471,566,677,1743,759,864,78,646,311,13,334,308,38,28,262,146,47,125
0.49819048944279026,2.22575796347679,0.736834876495512,0.8774087768247075,1.0631453851685053,-0.3409219722772057,1.087415425314427,0.2478813025768698,1.605631086088607,1.8832934520415403,3.451175716066335,-0.18327357472878134,3.253054371219224,1.289267000376432,0.2763076509973368,0.23360837776605786,0.6978221404482146,0.5387428051993683,0.402300331182603,-0.38919874485326694,0.30457623372576403,0.1905477242530135,2.379619278698563,0.44361639063605623,1.1356182999373312,3.4433864453496845,1.038761445699194,1.147599572470142,2.911763976530236,3.0892351012046553,1.289267000376432,1.8832934520415403,2.7725504193892325,1.965878763574573
2,719
Membrane lipid metabolic process
16
36
3.597217
0.000322
Q06136,Q13510,Q9NZ01,O15269,P06280,P17900,P07602,Q9NZJ7,P04062,Q96G23,P16278,P06865,Q16739,P50897,O43292,O95470
Processes and pathways
GO Biological process
msigdb_gobp
65,35,230,260,226,135,168,265,71,45,206,177,83,24,248,93
260,1070,248,563,682,93,71,1034,226,177,168,1818,206,135,2251,672,589,24,65,1391,35,83,1393,429,1148,688,1698,45,1281,420,679,1014,230,265,302,1404
1.289267000376432,0.014556932935040613,1.3471792062317862,0.5387428051993683,0.38845375763582707,2.245234151230295,2.5107215183813394,0.04431638803769443,1.4271945957883734,1.6275159466122078,1.69263057727874,-0.43794554085718024,1.5060072044287904,1.9247467241533158,-0.7062882632563935,0.402300331182603,0.5117436144293259,3.1471316821409943,2.5750940135788953,-0.18327357472878134,2.971565848245718,2.3511047492659554,-0.18327357472878134,0.78839669765801,-0.030413098045804464,0.38845375763582707,-0.3569626006240997,2.798926517414969,-0.12157226993528147,0.8139856344410125,0.402300331182603,0.07390195373379957,1.4271945957883734,1.2776071666564428,1.1595533384376537,-0.18327357472878134
2,719
Mitochondrial transmembrane transport
23
48
3.568636
0.000359
Q9UJS0,Q99595,P21796,Q9H2D1,P12236,O60830,O75964,Q9BQT8,O14925,O43772,P12235,O75746,O95202,P05141,Q9H9B4,P56385,Q6P4A7,O95831,Q15388,Q9BSK2,P24539,O43615,Q9Y619
Processes and pathways
GO Biological process
msigdb_gobp
262,6,12,13,143,19,34,311,54,437,186,449,326,327,334,336,210,465,219,221,98,379,125
54,379,437,19,727,1265,449,804,34,628,326,465,609,327,751,2430,186,143,12,478,98,2476,794,2520,629,781,852,336,566,219,714,210,799,989,2264,844,646,6,1230,311,221,13,334,1401,262,1087,1316,125
2.6657421041309006,0.8900005618991303,0.7626802321711698,3.317234140715181,0.332688904231155,-0.12157226993528147,0.736834876495512,0.2478813025768698,2.971565848245718,0.457314566306333,1.0631453851685053,0.6978221404482146,0.4846014092491796,1.0631453851685053,0.30457623372576403,-0.8995564994467704,1.605631086088607,1.8832934520415403,3.451175716066335,0.6847519362737263,2.215993204297903,-0.9536034576855446,0.26211431465637414,-1.0265997707300218,0.457314566306333,0.2763076509973368,0.20494183108481331,1.0265264066984594,0.5387428051993683,1.4611164567099202,0.34668734253092304,1.494820444712504,0.26211431465637414,0.08863020155351369,-0.7062882632563935,0.2192953010576298,0.44361639063605623,3.7466882849921066,-0.09100256702323781,1.1356182999373312,1.4498335257671533,3.4433864453496845,1.038761445699194,-0.18327357472878134,1.289267000376432,0.014556932935040613,-0.13692690238543065,1.965878763574573
2,719
Inner mitochondrial membrane protein complex
26
70
3.567096
0.000361
Q99595,P62072,Q9UDW1,P12236,O43676,O60830,Q16891,P03886,Q5XKP0,P13073,P47985,O75964,Q96CU9,O96000,P00403,Q9BUR5,Q96IX5,O14925,O14949,P14406,Q9P0J0,P56385,P24539,Q13505,Q9NX63,O75306
Localization
GO Cellular component
msigdb_gocc
6,10,14,143,15,19,404,26,155,286,408,34,39,426,305,179,441,54,72,73,204,336,98,105,367,244
856,54,72,15,19,872,244,1090,1924,804,34,858,1289,1598,426,305,26,751,1006,1796,1291,143,286,73,2317,1602,2225,504,444,638,98,2476,2693,1714,807,793,794,2279,408,2520,2559,769,852,336,10,105,1057,1307,404,714,1393,155,1061,799,989,39,441,6,593,1230,179,1401,721,608,367,204,14,1235,1316,502
0.1905477242530135,2.6657421041309006,2.4828960163826035,3.4199522827989974,3.317234140715181,0.17611273471205496,1.3586851022140123,-0.00038868636313022414,-0.5036894974780469,0.2478813025768698,2.971565848245718,0.1905477242530135,-0.13692690238543065,-0.3089938532666943,0.78839669765801,1.147599572470142,3.105839691433299,0.30457623372576403,0.07390195373379957,-0.421643782078971,-0.13692690238543065,1.8832934520415403,1.2189142308211247,2.4828960163826035,-0.7756984250375901,-0.3089938532666943,-0.6890863348428883,0.632136528586786,0.7497737515679389,0.44361639063605623,2.215993204297903,-0.9536034576855446,-2.0224789299810415,-0.37305474027032975,0.2478813025768698,0.26211431465637414,0.26211431465637414,-0.7235499894095512,0.826732699034428,-1.0265997707300218,-1.1006945383567346,0.29046154644551864,0.20494183108481331,1.0265264066984594,3.4899576845407503,2.1865914316960353,0.029458532651360454,-0.13692690238543065,0.8394483821163174,0.34668734253092304,-0.18327357472878134,1.7782191520986066,0.029458532651360454,0.26211431465637414,0.08863020155351369,2.894556239112553,0.7626802321711698,3.7466882849921066,0.5117436144293259,-0.09100256702323781,1.6275159466122078,-0.18327357472878134,0.34668734253092304,0.49819048944279026,0.9525040135933169,1.5394252878937733,3.427774762153474,-0.09100256702323781,-0.13692690238543065,0.6453409341751739
2,719
Ion transmembrane transporter activity
41
84
3.553409
0.00038
Q15043,Q9UJS0,P51790,Q9Y487,O43681,P21796,Q9H2D1,Q9UDW1,P12236,Q93050,Q9Y277,Q96QD8,P45880,P13073,P47985,O75964,Q9UBX3,P05023,P20020,Q96ES6,Q6NUK1,Q9C0H2,P00403,Q9BQT8,P12235,O43772,O75746,O95202,P05141,Q70HW3,Q8TB61,Q9H9B4,P56385,Q6P4A7,Q9Y5K8,P61421,P24539,Q7KZN9,Q9HD20,Q6P4Q7,Q9Y619
Functions
GO Molecular function
msigdb_gomf
386,262,261,395,389,12,13,14,143,401,146,147,22,286,408,34,38,295,170,300,299,49,305,311,186,437,449,326,327,76,78,334,336,210,341,348,98,364,120,122,125
2067,2040,389,437,600,449,804,34,326,305,295,327,751,2071,2103,806,1006,1291,186,143,286,547,170,504,877,2404,12,98,2476,807,794,515,2182,1385,22,408,2520,261,781,823,471,852,336,348,1715,566,1366,677,1304,759,883,386,864,2542,299,2337,210,122,76,364,989,78,2454,401,844,300,646,147,709,311,1256,49,13,334,120,38,14,973,262,146,395,341,125,2608
-0.587106244130671,-0.5703108638932032,0.8647862588625002,0.7626802321711698,0.49819048944279026,0.736834876495512,0.2478813025768698,2.971565848245718,1.0631453851685053,1.147599572470142,1.1714797320050525,1.0631453851685053,0.30457623372576403,-0.587106244130671,-0.6039584463179856,0.2478813025768698,0.07390195373379957,-0.13692690238543065,1.605631086088607,1.8832934520415403,1.2189142308211247,0.5656005771908399,1.6710149037139495,0.632136528586786,0.17611273471205496,-0.8638509468356808,3.451175716066335,2.215993204297903,-0.9536034576855446,0.2478813025768698,0.26211431465637414,0.6188981125431084,-0.6548601180580003,-0.18327357472878134,3.253054371219224,0.826732699034428,-1.0265997707300218,1.289267000376432,0.2763076509973368,0.23360837776605786,0.6978221404482146,0.20494183108481331,1.0265264066984594,0.9896472724402028,-0.37305474027032975,0.5387428051993683,-0.1677772467277911,0.402300331182603,-0.13692690238543065,0.30457623372576403,0.17611273471205496,0.8774087768247075,0.1905477242530135,-1.0635076502293486,1.1595533384376537,-0.7932038385838693,1.494820444712504,1.98632596881489,2.436197942025277,0.9525040135933169,0.08863020155351369,2.379619278698563,-0.9175064966386184,0.8521328477933847,0.2192953010576298,1.1595533384376537,0.44361639063605623,1.8728793126258834,0.3606474828614861,1.1356182999373312,-0.10626425831084813,2.763729779838205,3.4433864453496845,1.038761445699194,2.0066948267496136,2.911763976530236,3.427774762153474,0.10331578012873843,1.289267000376432,1.8832934520415403,0.8647862588625002,1.0265264066984594,1.965878763574573,-1.213975141317416
2,719
Intrinsic component of organelle membrane
56
113
3.531703
0.000413
Q9Y282,P51572,Q969X5,Q99595,O43819,Q15070,O15118,O60830,P27824,Q16891,Q5XKP0,O76024,P57088,Q16134,Q9P035,P20020,O75298,Q9BUR5,O14925,P10321,Q86XL3,P12235,P57105,Q03518,O43505,Q86YN1,Q9NPA0,Q8TB61,Q14739,Q9H9B4,Q5J8M3,O75844,Q6P4A7,Q8TCT8,Q96A33,Q9HCU5,Q15388,Q96HA9,O95470,Q15629,Q9NZ01,Q12981,Q5SNT2,Q13505,L0R6Q1,Q9UG56,Q9NX63,Q9NQC3,Q9Y512,P42892,Q9BUN8,O15258,Q9BWH2,Q9H3K2,Q8TCT9,O43292
Localization
GO Cellular component
msigdb_gocc
2,385,392,6,511,141,273,19,522,404,155,167,297,42,302,170,303,179,54,312,58,186,445,447,195,75,463,78,207,334,337,82,210,212,213,476,219,91,93,96,230,228,485,105,375,235,367,109,502,239,116,371,246,247,498,248
908,375,54,273,371,248,1481,195,600,511,19,303,1090,82,651,167,628,941,93,609,1457,312,186,170,911,1684,2367,522,2349,2279,239,629,1297,385,297,445,1270,1715,566,447,1328,228,105,1528,207,839,141,1392,219,96,42,1780,404,1393,337,485,155,210,1061,798,58,632,75,865,1494,1862,887,989,948,78,212,498,1170,688,1698,392,213,844,91,646,1281,1282,6,1230,2063,716,116,179,541,246,247,334,869,476,2671,463,109,721,367,230,302,1177,1672,235,1126,1015,2,737,830,803,1316,502,831
0.1471191126541989,0.9025617730365805,2.6657421041309006,1.2542091223510612,0.9275931030431922,1.3471792062317862,-0.23005094416154934,1.5726323086619758,0.49819048944279026,0.6188981125431084,3.317234140715181,1.147599572470142,-0.00038868636313022414,2.3511047492659554,0.4298814338746595,1.69263057727874,0.457314566306333,0.11795895191442474,2.245234151230295,0.4846014092491796,-0.2144101059765268,1.123609385664931,1.605631086088607,1.6710149037139495,0.1471191126541989,-0.3569626006240997,-0.8284013522129561,0.6056254989038173,-0.8107713240707701,-0.7235499894095512,1.3701657615426401,0.457314566306333,-0.13692690238543065,0.8774087768247075,1.1714797320050525,0.7497737515679389,-0.12157226993528147,-0.37305474027032975,0.5387428051993683,0.7497737515679389,-0.15232845914399104,1.4271945957883734,2.1865914316960353,-0.2614793772811411,1.5060072044287904,0.2192953010576298,1.9040605759318283,-0.18327357472878134,1.4611164567099202,2.22575796347679,2.807690107486791,-0.4053949717396913,0.8394483821163174,-0.18327357472878134,1.0265264066984594,0.671648454750572,1.7782191520986066,1.494820444712504,0.029458532651360454,0.26211431465637414,2.611536121609732,0.457314566306333,2.4455700591414438,0.1905477242530135,-0.23005094416154934,-0.4543006169521521,0.17611273471205496,0.08863020155351369,0.11795895191442474,2.379619278698563,1.483609806203434,0.6453409341751739,-0.04549245437206825,0.38845375763582707,-0.3569626006240997,0.8647862588625002,1.483609806203434,0.2192953010576298,2.2549457173407865,0.44361639063605623,-0.12157226993528147,-0.12157226993528147,3.7466882849921066,-0.09100256702323781,-0.5703108638932032,0.34668734253092304,2.087399401896311,1.6275159466122078,0.5923184989479339,1.3586851022140123,1.3586851022140123,1.038761445699194,0.1905477242530135,0.6978221404482146,-1.5704713475646683,0.7108592467728196,2.157026937488641,0.34668734253092304,0.9525040135933169,1.4271945957883734,1.1595533384376537,-0.04549245437206825,-0.3409219722772057,1.3930518398628324,-0.015378603154741318,0.07390195373379957,4.013195205240466,0.332688904231155,0.23360837776605786,0.26211431465637414,-0.13692690238543065,0.6453409341751739,0.23360837776605786
2,719
SLC superfamily of solute carriers
23
35
3.478922
0.000503
Q15043,Q9Y6C9,Q9UJS0,Q9NZJ7,Q9H2D1,P12236,Q96QD8,Q9UBX3,Q5T1Q4,Q6NUK1,Q9BQT8,P12235,O43772,O75746,Q96H78,O95202,P05141,Q70HW3,Q8IXU6,Q8TB61,Q9H9B4,Q9BSK2,Q9Y619
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
386,257,262,265,13,143,147,38,169,299,311,186,437,449,70,326,327,76,461,78,334,221,125
437,600,449,326,327,806,186,143,1385,781,823,471,566,677,386,864,169,2542,299,2337,76,461,78,70,646,147,311,221,13,334,265,38,262,125,257
0.7626802321711698,0.49819048944279026,0.736834876495512,1.0631453851685053,1.0631453851685053,0.2478813025768698,1.605631086088607,1.8832934520415403,-0.18327357472878134,0.2763076509973368,0.23360837776605786,0.6978221404482146,0.5387428051993683,0.402300331182603,0.8774087768247075,0.1905477242530135,1.6818338097384962,-1.0635076502293486,1.1595533384376537,-0.7932038385838693,2.436197942025277,0.7108592467728196,2.379619278698563,2.5199648159717087,0.44361639063605623,1.8728793126258834,1.1356182999373312,1.4498335257671533,3.4433864453496845,1.038761445699194,1.2776071666564428,2.911763976530236,1.289267000376432,1.965878763574573,1.3125089094881686
2,719
Vacuolar lumen
21
62
3.431908
0.000599
Q92820,O14773,P17900,P54802,Q9NZJ7,P38435,P50897,Q13510,P07602,P06865,Q14108,Q9BTY2,P04062,Q9UM22,P16278,Q8NHP8,P10619,P06280,Q8IV08,Q9Y5Z4,Q9UMR5
Localization
GO Cellular component
msigdb_gocc
258,134,135,264,265,139,24,35,168,177,193,194,71,205,206,216,89,226,232,236,121
658,134,389,1625,71,1034,226,177,2071,1320,168,1818,1133,380,89,275,1240,2073,822,206,135,693,1770,2181,139,2636,1775,24,1875,2227,1244,1420,264,2228,1577,446,987,1508,2132,1857,928,35,193,2433,232,2293,216,258,691,2092,699,1084,194,1104,2199,719,2536,265,205,121,2065,236
0.41610948501277006,1.9247467241533158,0.8647862588625002,-0.32493250526949763,2.5107215183813394,0.04431638803769443,1.4271945957883734,1.6275159466122078,-0.587106244130671,-0.15232845914399104,1.69263057727874,-0.43794554085718024,-0.030413098045804464,0.8900005618991303,2.2936167157241867,1.2424706616319041,-0.10626425831084813,-0.587106244130671,0.23360837776605786,1.5060072044287904,1.9247467241533158,0.37456954772114676,-0.4053949717396913,-0.6548601180580003,1.9040605759318283,-1.3299369864356707,-0.4053949717396913,3.1471316821409943,-0.47070938318962924,-0.6890863348428883,-0.10626425831084813,-0.19881775585569805,1.2776071666564428,-0.6890863348428883,-0.2931056735100328,0.7497737515679389,0.08863020155351369,-0.24574059272730153,-0.620867881511793,-0.4543006169521521,0.13255997690276794,2.971565848245718,1.5836549017230799,-0.8995564994467704,1.404457491582026,-0.7408719578287188,1.4723751800675877,1.3009008737170185,0.38845375763582707,-0.587106244130671,0.37456954772114676,0.014556932935040613,1.5836549017230799,-0.00038868636313022414,-0.6548601180580003,0.34668734253092304,-1.0450191132829518,1.2776071666564428,1.5394252878937733,2.0066948267496136,-0.5703108638932032,1.3930518398628324
2,719
Active transmembrane transporter activity
29
62
3.418733
0.000629
Q15043,P51790,Q9UDW1,P12236,O43676,Q96QD8,P03886,P13073,P47985,Q9UBX3,P05023,P20020,O96000,Q96ES6,P00403,P12235,Q03518,P08183,O95202,P05141,Q9P0J0,Q9Y5K8,P55011,Q15388,P61421,Q9HD20,Q7KZN9,O75306,P20674
Functions
GO Molecular function
msigdb_gomf
386,261,14,143,15,147,26,286,408,38,295,170,426,300,305,186,447,322,326,327,204,341,471,219,348,120,364,244,504
856,15,727,872,244,1924,858,1289,326,1598,426,305,26,295,327,751,322,806,1006,1291,186,143,286,547,2225,170,504,877,2404,740,2693,807,515,2182,1385,408,2559,261,769,781,823,471,348,566,677,447,386,219,864,1057,1307,364,989,300,147,120,2671,204,38,14,973,341
0.1905477242530135,3.4199522827989974,0.332688904231155,0.17611273471205496,1.3586851022140123,-0.5036894974780469,0.1905477242530135,-0.13692690238543065,1.0631453851685053,-0.3089938532666943,0.78839669765801,1.147599572470142,3.105839691433299,1.1714797320050525,1.0631453851685053,0.30457623372576403,1.087415425314427,0.2478813025768698,0.07390195373379957,-0.13692690238543065,1.605631086088607,1.8832934520415403,1.2189142308211247,0.5656005771908399,-0.6890863348428883,1.6710149037139495,0.632136528586786,0.17611273471205496,-0.8638509468356808,0.3186519434677123,-2.0224789299810415,0.2478813025768698,0.6188981125431084,-0.6548601180580003,-0.18327357472878134,0.826732699034428,-1.1006945383567346,1.289267000376432,0.29046154644551864,0.2763076509973368,0.23360837776605786,0.6978221404482146,0.9896472724402028,0.5387428051993683,0.402300331182603,0.7497737515679389,0.8774087768247075,1.4611164567099202,0.1905477242530135,0.029458532651360454,-0.13692690238543065,0.9525040135933169,0.08863020155351369,1.1595533384376537,1.8728793126258834,2.0066948267496136,-1.5704713475646683,1.5394252878937733,2.911763976530236,3.427774762153474,0.10331578012873843,1.0265264066984594
2,719
Predicted membrane proteins
224
461
3.404715
0.000662
Q96CP7,Q9Y282,Q9NX00,Q99595,Q8N0U8,P24390,Q9NS69,Q9UDW1,O43676,O43657,O60830,Q9P2W9,Q15800,P03886,Q9H061,Q9BQE5,P30519,Q9Y262,O75964,Q99720,P43307,Q9UBX3,P09601,O60637,Q16134,Q96G23,O95197,Q3SXM5,Q8WY22,Q8N511,Q9C0H2,O43169,Q15392,Q8NCH0,O14925,Q86XL3,O15127,Q96A26,P51648,Q06136,Q4ZIN3,Q15363,Q96H78,O00461,Q86YN1,Q70HW3,O60725,Q8TB61,Q9UGP8,O60476,O75844,Q16739,Q9NPR9,Q14849,Q96HA9,Q9BTX1,O95470,Q15629,O60831,P24539,Q86UE4,Q13505,Q9H4I3,O15173,O43760,Q9NQC3,Q8WTV0,Q9NR28,Q5VW38,Q9UIQ6,Q9BUN8,Q9Y5M8,Q9HD20,Q6P4Q7,Q9Y619,Q9H6V9,Q96PC5,Q96N66,O94919,Q9HD45,Q15070,P38435,P12236,Q96QD8,P31350,O96005,P67812,Q16850,Q8WVC6,Q9H1E5,O76024,Q5T1Q4,Q9UBV2,P20020,Q9BUR5,Q8N8L6,P12235,P62942,Q08722,Q14108,Q9Y3B3,Q9P0J0,O75845,Q14739,Q6P4A7,Q07065,Q8TCT8,Q96A33,Q9NQX7,Q15388,Q9BSK2,Q9UDX5,Q10472,Q9H6K4,Q9NZ01,Q12981,Q8IV08,O95772,Q9UG56,P16435,Q15904,P42892,O75306,P46977,Q9H3K2,O43292,Q53GQ0,Q9NR77,Q9UBU6,Q9Y2W6,Q9Y6C9,O15269,P51790,P35613,Q9NZJ7,Q8NHS3,O15118,Q9BZF1,Q6NUQ4,Q96KA5,P48651,P11117,Q15005,P13073,Q8N1F7,Q9NX40,Q96JX3,P05023,P57088,Q9H2U1,Q9P035,Q96ES6,O75298,P00403,P10321,P08183,O95202,P05141,O15260,Q96SK2,Q9H6H4,Q9H9B4,O00264,Q5J8M3,Q8IZA0,Q9UKR5,Q70UQ0,Q6UW68,Q92804,Q9NPL8,Q16513,Q99523,Q7KZN9,Q8WVI0,O15258,Q8NF37,Q07820,O15031,Q6IAN0,Q15043,O75915,P51572,Q969X5,Q9Y487,Q93050,P50402,Q9BT22,Q9H3N1,Q9BXK5,Q9Y3E0,O75381,Q12907,Q8TBA6,Q99735,Q8NBX0,Q96IX5,Q9UII4,O43772,P57105,Q03518,Q92542,P02786,O14828,Q6ZXV5,Q8NC54,Q9NPA0,Q8IXU6,Q00765,Q9HCU5,P49257,P55011,O95831,P20645,Q96AG4,Q9Y320,Q5SNT2,Q96TC7,O95864,Q8TCT9,Q7RTS9,P49755,P51571,Q96FV9,Q9H1A4
Functions
Protein Atlas Protein class
protein_atlas_protein_class
0,2,3,6,7,9,11,14,15,17,19,20,23,26,27,29,30,32,34,36,37,38,40,41,42,45,43,44,46,48,49,50,52,56,54,58,59,62,64,65,68,69,70,74,75,76,77,78,79,80,82,83,84,87,91,92,93,96,95,98,103,105,106,107,108,109,110,111,114,115,116,119,120,122,125,129,128,127,126,137,141,139,143,147,150,151,152,154,158,159,167,169,173,170,179,183,186,187,188,193,202,204,203,207,210,211,212,213,214,219,221,222,224,225,230,228,232,233,235,238,240,239,244,245,247,248,251,253,255,256,257,260,261,263,265,270,273,281,279,280,277,275,283,286,287,291,289,295,297,298,302,300,303,305,312,322,326,327,330,332,333,334,335,337,338,345,343,342,351,352,355,365,364,369,371,373,377,376,387,386,383,385,392,395,401,403,412,414,413,415,417,418,419,420,429,441,442,437,445,447,453,450,454,458,462,463,461,460,476,470,471,465,467,481,483,485,488,490,498,496,495,506,508,509
908,533,2690,975,2222,335,74,856,2653,1068,454,978,54,724,2556,376,273,59,107,371,330,260,1070,738,50,248,563,1922,17,15,108,437,600,511,1454,1264,80,980,41,77,19,95,727,303,244,417,2545,1004,650,2401,1596,82,203,651,383,34,514,167,1709,628,126,941,858,43,326,981,93,1182,601,233,465,490,151,2489,1625,305,450,26,1457,873,1711,295,327,1650,2290,322,806,1006,1819,40,1796,312,1682,275,1895,1292,956,186,143,286,1602,238,547,652,170,467,1412,2475,9,98,672,522,740,849,30,150,1851,1111,924,752,263,1549,2597,139,1199,1385,1358,1459,239,37,1575,245,1901,277,470,495,403,629,673,2694,506,385,64,261,2599,2302,1244,823,1114,471,852,1855,297,445,674,1462,1164,1715,1997,1115,187,152,566,460,1465,677,447,65,1741,211,377,1466,2701,188,224,2551,1273,631,418,228,1222,2081,1688,1274,1304,105,2305,193,1430,1329,1528,641,759,207,592,87,2627,283,386,783,141,2614,69,219,52,96,988,2643,864,23,240,42,355,1780,83,1307,154,570,696,44,714,1744,68,251,1436,1077,337,2482,1557,784,2084,485,1829,1308,169,2632,760,114,387,2542,279,885,2337,210,122,2393,2191,342,1724,458,76,343,364,496,619,746,817,2292,103,798,58,632,75,232,1694,865,1494,461,338,7,287,1727,529,48,1012,1862,183,1438,866,429,462,887,1148,56,989,373,826,270,948,78,419,1440,212,498,1192,110,158,369,1170,931,46,453,2163,1309,905,688,1496,707,969,351,643,401,1698,689,392,62,213,481,0,691,2140,844,300,508,45,70,91,1475,1101,441,289,280,560,918,127,646,128,734,147,1281,709,332,763,889,488,1282,2092,365,1563,6,1750,36,420,679,666,2308,29,993,2063,221,412,716,1446,92,116,179,2718,541,1256,932,413,281,49,2554,2098,27,509,159,2200,298,247,414,2327,106,333,225,1836,129,334,476,120,137,2471,2671,1174,463,352,84,109,214,111,253,11,574,519,1347,721,2328,3,608,291,1014,1917,230,265,302,204,1404,1918,1177,20,1672,2203,255,173,38,14,222,235,79,1126,1015,1030,1031,442,115,345,1839,1541,32,1704,1235,2,871,737,256,483,562,202,830,415,1156,1352,395,1212,1316,119,1262,125,831,257
0.1471191126541989,0.5923184989479339,-1.9330494440790569,0.08863020155351369,-0.6890863348428883,1.0265264066984594,2.4549258649549612,0.1905477242530135,-1.4487189783210372,0.014556932935040613,0.723863433268658,0.08863020155351369,2.6657421041309006,0.332688904231155,-1.1006945383567346,0.9025617730365805,1.2542091223510612,2.6024486449078035,2.1767547750820517,0.9275931030431922,1.0509677239800752,1.289267000376432,0.014556932935040613,0.3186519434677123,2.7548947540582653,1.3471792062317862,0.5387428051993683,-0.5036894974780469,3.3727823469299025,3.4199522827989974,2.157026937488641,0.7626802321711698,0.49819048944279026,0.6188981125431084,-0.2144101059765268,-0.12157226993528147,2.370131263440487,0.08863020155351369,2.833896232595042,2.379619278698563,3.317234140715181,2.22575796347679,0.332688904231155,1.147599572470142,1.3586851022140123,0.8139856344410125,-1.082065937615682,0.07390195373379957,0.4298814338746595,-0.8638509468356808,-0.3089938532666943,2.3511047492659554,1.5394252878937733,0.4298814338746595,0.8774087768247075,2.971565848245718,0.6188981125431084,1.69263057727874,-0.37305474027032975,0.457314566306333,1.945352566311608,0.11795895191442474,0.1905477242530135,2.798926517414969,1.0631453851685053,0.08863020155351369,2.245234151230295,-0.0606169582349026,0.49819048944279026,1.3930518398628324,0.6978221404482146,0.6585115148857332,1.8310169016228028,-0.9717514496482177,-0.32493250526949763,1.147599572470142,0.736834876495512,3.105839691433299,-0.2144101059765268,0.17611273471205496,-0.37305474027032975,1.1714797320050525,1.0631453851685053,-0.3409219722772057,-0.7408719578287188,1.087415425314427,0.2478813025768698,0.07390195373379957,-0.43794554085718024,2.859976400730297,-0.421643782078971,1.123609385664931,-0.3569626006240997,1.2424706616319041,-0.48717221640031005,-0.13692690238543065,0.10331578012873843,1.605631086088607,1.8832934520415403,1.2189142308211247,-0.3089938532666943,1.3816213018328303,0.5656005771908399,0.4298814338746595,1.6710149037139495,0.6978221404482146,-0.19881775585569805,-0.9536034576855446,3.672408462929854,2.215993204297903,0.402300331182603,0.6056254989038173,0.3186519434677123,0.20494183108481331,3.0475012788562985,1.851989450905129,-0.4543006169521521,-0.015378603154741318,0.13255997690276794,0.30457623372576403,1.2776071666564428,-0.2772676267666931,-1.213975141317416,1.9040605759318283,-0.07578689853775272,-0.18327357472878134,-0.1677772467277911,-0.2144101059765268,1.3701657615426401,2.9203474611613784,-0.2931056735100328,1.3586851022140123,-0.48717221640031005,1.2424706616319041,0.6978221404482146,0.6453409341751739,0.8394483821163174,0.457314566306333,0.402300331182603,-2.067826833333904,0.632136528586786,0.8774087768247075,2.5750940135788953,1.289267000376432,-1.213975141317416,-0.7582546181179882,-0.10626425831084813,0.23360837776605786,-0.015378603154741318,0.6978221404482146,0.20494183108481331,-0.4543006169521521,1.1714797320050525,0.7497737515679389,0.402300331182603,-0.2144101059765268,-0.04549245437206825,-0.37305474027032975,-0.5368889474821656,-0.015378603154741318,1.605631086088607,1.8310169016228028,0.5387428051993683,0.7108592467728196,-0.2144101059765268,0.402300331182603,0.7497737515679389,2.5750940135788953,-0.38919874485326694,1.483609806203434,0.9025617730365805,-0.2144101059765268,-2.3979222331766588,1.605631086088607,1.4385262761005175,-1.082065937615682,-0.12157226993528147,0.457314566306333,0.8139856344410125,1.4271945957883734,-0.09100256702323781,-0.587106244130671,-0.3569626006240997,-0.12157226993528147,-0.13692690238543065,2.1865914316960353,-0.7582546181179882,1.5836549017230799,-0.19881775585569805,-0.15232845914399104,-0.2614793772811411,0.44361639063605623,0.30457623372576403,1.5060072044287904,0.5117436144293259,2.3128479941750375,-1.2909767695650514,1.2307057402478268,0.8774087768247075,0.2763076509973368,1.9040605759318283,-1.233112298811929,2.5199648159717087,1.4611164567099202,2.74604529197796,2.22575796347679,0.08863020155351369,-1.3495342310278062,0.1905477242530135,3.2287919262177374,1.3701657615426401,2.807690107486791,0.9772957319876318,-0.4053949717396913,2.3511047492659554,-0.13692690238543065,1.7888209300317397,0.5387428051993683,0.37456954772114676,2.798926517414969,0.34668734253092304,-0.38919874485326694,2.5475999117636636,1.335647955135846,-0.19881775585569805,0.014556932935040613,1.0265264066984594,-0.9536034576855446,-0.2772676267666931,0.2763076509973368,-0.587106244130671,0.671648454750572,-0.43794554085718024,-0.13692690238543065,1.6818338097384962,-1.31041805381167,0.30457623372576403,2.097402027546233,0.8774087768247075,-1.0635076502293486,1.2424706616319041,0.17611273471205496,-0.7932038385838693,1.494820444712504,1.98632596881489,-0.8460943992105768,-0.6548601180580003,1.014262462244214,-0.37305474027032975,0.723863433268658,2.436197942025277,1.014262462244214,0.9525040135933169,0.6453409341751739,0.4846014092491796,0.3186519434677123,0.2478813025768698,-0.7408719578287188,2.1964100084149285,0.2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2,719
Protein localization to mitochondrion
23
53
3.386457
0.000708
Q9Y371,Q9Y6C9,P51572,Q99595,Q15070,P62072,Q9NS69,P52789,O60830,P49840,Q5JRX3,O14925,Q99797,Q9P0J0,Q9UBE0,P49257,O95831,Q15388,Q8N4H5,P55786,Q9Y512,O14737,O43615
Processes and pathways
GO Biological process
msigdb_gobp
520,257,385,6,141,10,11,278,19,432,53,54,201,204,340,470,465,219,104,491,502,368,379
1621,2147,1180,368,54,563,379,19,1265,628,941,465,609,1133,1036,2430,660,1019,1896,1356,1242,2076,470,432,385,278,491,10,2111,1391,540,141,219,2232,714,1393,53,2292,104,948,6,201,1401,11,204,340,998,1235,520,830,502,2672,257
-0.32493250526949763,-0.6378349653375106,-0.0606169582349026,0.9400635335930252,2.6657421041309006,0.5387428051993683,0.8900005618991303,3.317234140715181,-0.12157226993528147,0.457314566306333,0.11795895191442474,0.6978221404482146,0.4846014092491796,-0.030413098045804464,0.04431638803769443,-0.8995564994467704,0.41610948501277006,0.05913077172037472,-0.48717221640031005,-0.1677772467277911,-0.10626425831084813,-0.587106244130671,0.6978221404482146,0.7755544905767453,0.8774087768247075,1.2424706616319041,0.6585115148857332,3.4899576845407503,-0.6039584463179856,-0.18327357472878134,0.5923184989479339,1.9040605759318283,1.4611164567099202,-0.6890863348428883,0.34668734253092304,-0.18327357472878134,2.701579665755794,-0.7408719578287188,2.1964100084149285,0.11795895191442474,3.7466882849921066,1.5615865779228295,-0.18327357472878134,3.474477642713755,1.5394252878937733,1.0265264066984594,0.08863020155351369,-0.09100256702323781,0.6188981125431084,0.23360837776605786,0.6453409341751739,-1.5704713475646683,1.3125089094881686
2,719
er
39
75
3.383661
0.000715
Q96N66,O75915,P51572,O15269,Q9Y487,Q9NR31,P27824,Q9BZF1,Q9P2W9,P48651,O96005,Q16850,Q9Y3E0,P51151,Q15392,Q9NTJ5,Q06136,Q15363,Q9NPA0,O75845,Q00765,Q14739,Q9H6H4,Q5J8M3,O00264,Q07065,Q96A33,Q9UKR5,O95470,Q16513,Q12981,Q969Q5,P61026,O15173,Q9NQC3,P46977,P49755,Q9Y5M8,Q8NF37
Localization
OpenCell Localization
opencell_localization
127,383,385,260,395,531,522,281,20,277,151,154,415,427,52,574,65,69,463,203,460,207,333,337,335,211,213,345,93,355,228,378,492,107,109,245,495,119,373
335,107,260,1070,1481,1052,1004,203,383,981,93,601,151,2489,1625,873,1711,1989,1323,1713,522,1199,245,1359,277,495,427,1776,385,2228,1462,2156,492,1997,1271,460,65,211,228,207,839,69,52,2643,355,154,337,2337,2493,1862,887,373,572,2294,2340,378,689,213,127,1750,2063,281,333,1174,463,109,531,574,1404,20,345,415,395,119,974
1.0265264066984594,2.1767547750820517,1.289267000376432,0.014556932935040613,-0.23005094416154934,0.029458532651360454,0.07390195373379957,1.5394252878937733,0.8774087768247075,0.08863020155351369,2.245234151230295,0.49819048944279026,1.8310169016228028,-0.9717514496482177,-0.32493250526949763,0.17611273471205496,-0.37305474027032975,-0.5368889474821656,-0.15232845914399104,-0.37305474027032975,0.6056254989038173,-0.07578689853775272,1.3586851022140123,-0.1677772467277911,1.2424706616319041,0.6453409341751739,0.78839669765801,-0.4053949717396913,0.8774087768247075,-0.6890863348428883,-0.2144101059765268,-0.6378349653375106,0.6585115148857332,-0.5368889474821656,-0.12157226993528147,0.7108592467728196,2.5750940135788953,1.483609806203434,1.4271945957883734,1.5060072044287904,0.2192953010576298,2.5199648159717087,2.74604529197796,-1.3495342310278062,0.9772957319876318,1.7888209300317397,1.0265264066984594,-0.7932038385838693,-0.9717514496482177,-0.4543006169521521,0.17611273471205496,0.9150925679330987,0.5387428051993683,-0.7408719578287188,-0.7932038385838693,0.9025617730365805,0.38845375763582707,1.483609806203434,1.945352566311608,-0.38919874485326694,-0.5703108638932032,1.2424706616319041,1.038761445699194,-0.04549245437206825,0.7108592467728196,2.157026937488641,0.6056254989038173,0.5387428051993683,-0.18327357472878134,3.317234140715181,1.014262462244214,0.826732699034428,0.8647862588625002,2.037102603070871,0.10331578012873843
2,719
Mitochondrial transport
34
77
3.367756
0.000758
P51572,Q9UJS0,Q99595,P62072,Q9NS69,Q15070,P52789,O60830,P45880,O75964,Q9UBX3,Q6NUK1,P49840,Q5JRX3,O14925,P12235,O43772,P05141,Q99797,Q9P0J0,P56385,Q9UBE0,P49257,Q14849,O95831,Q15388,P23786,P24539,Q8N4H5,Q9Y5Z4,P55786,Q9Y512,O14737,O43615
Processes and pathways
GO Biological process
msigdb_gobp
385,262,6,10,11,141,278,19,22,34,38,299,432,53,54,186,437,327,201,204,336,340,470,87,465,219,478,98,104,236,491,502,368,379
1621,368,54,563,379,437,19,1090,1265,804,34,628,941,465,609,1795,327,751,1133,712,2430,186,1896,478,98,2476,1485,1356,2076,794,2501,22,2520,470,432,629,385,278,491,852,336,10,2111,1391,540,87,141,219,2232,1780,714,1393,53,299,2292,865,1494,104,948,786,2165,6,201,1401,11,204,340,38,998,262,1087,1235,520,830,502,2672,236
-0.32493250526949763,0.9400635335930252,2.6657421041309006,0.5387428051993683,0.8900005618991303,0.7626802321711698,3.317234140715181,-0.00038868636313022414,-0.12157226993528147,0.2478813025768698,2.971565848245718,0.457314566306333,0.11795895191442474,0.6978221404482146,0.4846014092491796,-0.421643782078971,1.0631453851685053,0.30457623372576403,-0.030413098045804464,0.34668734253092304,-0.8995564994467704,1.605631086088607,-0.48717221640031005,0.6847519362737263,2.215993204297903,-0.9536034576855446,-0.23005094416154934,-0.1677772467277911,-0.587106244130671,0.26211431465637414,-0.9899664782882975,3.253054371219224,-1.0265997707300218,0.6978221404482146,0.7755544905767453,0.457314566306333,0.8774087768247075,1.2424706616319041,0.6585115148857332,0.20494183108481331,1.0265264066984594,3.4899576845407503,-0.6039584463179856,-0.18327357472878134,0.5923184989479339,2.3128479941750375,1.9040605759318283,1.4611164567099202,-0.6890863348428883,-0.4053949717396913,0.34668734253092304,-0.18327357472878134,2.701579665755794,1.1595533384376537,-0.7408719578287188,0.1905477242530135,-0.23005094416154934,2.1964100084149285,0.11795895191442474,0.2763076509973368,-0.6378349653375106,3.7466882849921066,1.5615865779228295,-0.18327357472878134,3.474477642713755,1.5394252878937733,1.0265264066984594,2.911763976530236,0.08863020155351369,1.289267000376432,0.014556932935040613,-0.09100256702323781,0.6188981125431084,0.23360837776605786,0.6453409341751739,-1.5704713475646683,1.3930518398628324
2,719
SLC25 family of mitochondrial transporters
15
20
3.34049
0.000836
Q9Y6C9,Q9UJS0,Q9UBX3,Q96H78,P12235,Q9NZJ7,P05141,Q70HW3,Q9H2D1,Q6NUK1,P12236,Q9BQT8,Q9Y619,O43772,Q9BSK2
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
257,262,38,70,186,265,327,76,13,299,143,311,125,437,221
437,600,449,327,186,143,781,566,677,299,76,70,311,221,13,265,38,262,125,257
0.7626802321711698,0.49819048944279026,0.736834876495512,1.0631453851685053,1.605631086088607,1.8832934520415403,0.2763076509973368,0.5387428051993683,0.402300331182603,1.1595533384376537,2.436197942025277,2.5199648159717087,1.1356182999373312,1.4498335257671533,3.4433864453496845,1.2776071666564428,2.911763976530236,1.289267000376432,1.965878763574573,1.3125089094881686
2,719
Mitochondrial carrier domain superfamily [IPR023395]
15
20
3.34049
0.000836
Q9Y6C9,Q9UJS0,Q9UBX3,Q96H78,P12235,Q9NZJ7,P05141,Q70HW3,Q9H2D1,Q6NUK1,P12236,Q9BQT8,Q9Y619,O43772,Q9BSK2
Sequence
InterPro Superfamily
interpro_homologous_superfamily
257,262,38,70,186,265,327,76,13,299,143,311,125,437,221
437,600,449,327,186,143,781,566,677,299,76,70,311,221,13,265,38,262,125,257
0.7626802321711698,0.49819048944279026,0.736834876495512,1.0631453851685053,1.605631086088607,1.8832934520415403,0.2763076509973368,0.5387428051993683,0.402300331182603,1.1595533384376537,2.436197942025277,2.5199648159717087,1.1356182999373312,1.4498335257671533,3.4433864453496845,1.2776071666564428,2.911763976530236,1.289267000376432,1.965878763574573,1.3125089094881686
2,719
Mitochondrial substrate/solute carrier [IPR018108]
15
20
3.34049
0.000836
Q9Y6C9,Q9UJS0,Q9UBX3,Q96H78,P12235,Q9NZJ7,P05141,Q70HW3,Q9H2D1,Q6NUK1,P12236,Q9BQT8,Q9Y619,O43772,Q9BSK2
Sequence
InterPro Repeat
interpro_repeat
257,262,38,70,186,265,327,76,13,299,143,311,125,437,221
437,600,449,327,186,143,781,566,677,299,76,70,311,221,13,265,38,262,125,257
0.7626802321711698,0.49819048944279026,0.736834876495512,1.0631453851685053,1.605631086088607,1.8832934520415403,0.2763076509973368,0.5387428051993683,0.402300331182603,1.1595533384376537,2.436197942025277,2.5199648159717087,1.1356182999373312,1.4498335257671533,3.4433864453496845,1.2776071666564428,2.911763976530236,1.289267000376432,1.965878763574573,1.3125089094881686
2,719
Intrinsic component of mitochondrial membrane
25
44
3.319982
0.0009
Q99595,O43819,Q15070,O60830,Q16891,Q5XKP0,Q16134,Q9BUR5,O14925,P12235,Q00325,P57105,Q9H9B4,Q6P4A7,Q15388,P50416,Q13505,Q9NX63,Q9UG56,O96008,Q9Y512,Q9BWH2,Q9H3K2,O94826,Q96NB2
Localization
GO Cellular component
msigdb_gocc
6,511,141,19,404,155,42,179,54,186,566,445,334,210,219,629,105,367,235,609,502,246,247,628,646
54,511,19,1090,651,628,941,609,186,2279,629,445,566,105,141,219,42,1780,404,1393,155,210,1061,865,1494,989,948,844,646,6,1230,179,246,247,334,869,2671,721,367,235,1126,830,1316,502
2.6657421041309006,0.6188981125431084,3.317234140715181,-0.00038868636313022414,0.4298814338746595,0.457314566306333,0.11795895191442474,0.4846014092491796,1.605631086088607,-0.7235499894095512,0.457314566306333,0.7497737515679389,0.5387428051993683,2.1865914316960353,1.9040605759318283,1.4611164567099202,2.807690107486791,-0.4053949717396913,0.8394483821163174,-0.18327357472878134,1.7782191520986066,1.494820444712504,0.029458532651360454,0.1905477242530135,-0.23005094416154934,0.08863020155351369,0.11795895191442474,0.2192953010576298,0.44361639063605623,3.7466882849921066,-0.09100256702323781,1.6275159466122078,1.3586851022140123,1.3586851022140123,1.038761445699194,0.1905477242530135,-1.5704713475646683,0.34668734253092304,0.9525040135933169,1.3930518398628324,-0.015378603154741318,0.23360837776605786,-0.13692690238543065,0.6453409341751739
2,719
Abnormality of head blood vessel
9
22
3.264643
0.001096
Q13510,P17900,P07602,Q9NZJ7,P21964,P16278,P06865,P10619,P03886
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
35,135,168,265,171,206,177,89,26
1705,1017,1108,26,177,168,1818,89,1821,206,135,171,1161,277,2185,2215,35,1804,1064,265,1520,803
-0.37305474027032975,0.05913077172037472,-0.015378603154741318,3.105839691433299,1.6275159466122078,1.69263057727874,-0.43794554085718024,2.2936167157241867,-0.43794554085718024,1.5060072044287904,1.9247467241533158,1.6710149037139495,-0.04549245437206825,1.2424706616319041,-0.6548601180580003,-0.6719437646434965,2.971565848245718,-0.421643782078971,0.029458532651360454,1.2776071666564428,-0.24574059272730153,0.26211431465637414
2,719
Ceramide metabolic process
8
18
3.264149
0.001098
Q13510,P06280,P17900,P04062,Q96G23,P06865,Q16739,O95470
Processes and pathways
GO Biological process
msigdb_gobp
35,226,135,71,45,177,83,93
260,1070,563,93,71,226,177,1818,135,672,589,35,83,1393,1148,45,679,1014
1.289267000376432,0.014556932935040613,0.5387428051993683,2.245234151230295,2.5107215183813394,1.4271945957883734,1.6275159466122078,-0.43794554085718024,1.9247467241533158,0.402300331182603,0.5117436144293259,2.971565848245718,2.3511047492659554,-0.18327357472878134,-0.030413098045804464,2.798926517414969,0.402300331182603,0.07390195373379957
2,719
Steroid binding
11
19
3.238316
0.001202
Q14108,P05023,P04062,O95772,O15173,P38435,P21796,O15118,Q9BZF1,P45880,Q14849
Functions
GO Molecular function
msigdb_gomf
193,295,71,233,107,139,12,273,281,22,87
335,273,107,1762,233,71,295,2103,12,2251,1137,139,22,446,193,87,1396,1343,281
1.0265264066984594,1.2542091223510612,2.1767547750820517,-0.4053949717396913,1.3930518398628324,2.5107215183813394,1.1714797320050525,-0.6039584463179856,3.451175716066335,-0.7062882632563935,-0.030413098045804464,1.9040605759318283,3.253054371219224,0.7497737515679389,1.5836549017230799,2.3128479941750375,-0.18327357472878134,-0.15232845914399104,1.2424706616319041
2,719
Intrinsic component of mitochondrial inner membrane
13
28
3.237033
0.001208
Q99595,Q13505,Q15070,Q16134,Q9NX63,Q9UG56,Q9H9B4,Q6P4A7,O60830,Q9BUR5,Q9H3K2,O14925,Q5XKP0
Localization
GO Cellular component
msigdb_gocc
6,105,141,42,367,235,334,210,19,179,247,54,155
54,511,19,1090,651,2279,566,105,141,42,404,1393,155,210,1061,989,844,646,6,179,247,334,869,721,367,235,1316,502
2.6657421041309006,0.6188981125431084,3.317234140715181,-0.00038868636313022414,0.4298814338746595,-0.7235499894095512,0.5387428051993683,2.1865914316960353,1.9040605759318283,2.807690107486791,0.8394483821163174,-0.18327357472878134,1.7782191520986066,1.494820444712504,0.029458532651360454,0.08863020155351369,0.2192953010576298,0.44361639063605623,3.7466882849921066,1.6275159466122078,1.3586851022140123,1.038761445699194,0.1905477242530135,0.34668734253092304,0.9525040135933169,1.3930518398628324,-0.13692690238543065,0.6453409341751739
2,719
Active ion transmembrane transporter activity
22
35
3.226458
0.001253
Q15043,P36543,P51790,Q9UDW1,P12236,Q96QD8,P13073,P47985,P05023,P16615,P20020,Q96ES6,P00403,P12235,O95202,P05141,Q9Y5K8,P55011,P61421,P20674,Q7KZN9,Q9HD20
Functions
GO Molecular function
msigdb_gomf
386,515,261,14,143,147,286,408,295,547,170,300,305,186,326,327,341,471,348,504,364,120
326,305,295,327,751,806,1006,1291,186,143,286,547,170,504,877,2404,807,515,2182,1385,408,261,781,471,348,566,677,386,364,300,147,120,14,973,341
1.0631453851685053,1.147599572470142,1.1714797320050525,1.0631453851685053,0.30457623372576403,0.2478813025768698,0.07390195373379957,-0.13692690238543065,1.605631086088607,1.8832934520415403,1.2189142308211247,0.5656005771908399,1.6710149037139495,0.632136528586786,0.17611273471205496,-0.8638509468356808,0.2478813025768698,0.6188981125431084,-0.6548601180580003,-0.18327357472878134,0.826732699034428,1.289267000376432,0.2763076509973368,0.6978221404482146,0.9896472724402028,0.5387428051993683,0.402300331182603,0.8774087768247075,0.9525040135933169,1.1595533384376537,1.8728793126258834,2.0066948267496136,3.427774762153474,0.10331578012873843,1.0265264066984594
2,719
Organophosphate ester transport
11
20
3.219861
0.001283
Q14108,P08183,Q9H2D1,Q6NUK1,P12236,Q8TB61,Q8WTV0,Q9BZF1,P12235,Q08722,Q9BSK2
Processes and pathways
GO Biological process
msigdb_gobp
193,322,13,299,143,78,110,281,186,188,221
600,327,322,186,143,2251,1137,1385,753,446,188,193,299,746,78,110,221,281,13,1404
0.49819048944279026,1.0631453851685053,1.087415425314427,1.605631086088607,1.8832934520415403,-0.7062882632563935,-0.030413098045804464,-0.18327357472878134,0.30457623372576403,0.7497737515679389,1.605631086088607,1.5836549017230799,1.1595533384376537,0.3186519434677123,2.379619278698563,2.1471356130946906,1.4498335257671533,1.2424706616319041,3.4433864453496845,-0.18327357472878134
2,719
Glycosphingolipid metabolism
9
15
3.205847
0.001347
Q13510,P06280,P17900,P07602,P04062,P16278,P06865,Q16739,P10619
Processes and pathways
Reactome Pathways
msigdb_reactome
35,226,135,168,71,206,177,83,89
908,389,71,226,177,168,1818,89,206,135,35,83,2063,1014,265
0.1471191126541989,0.8647862588625002,2.5107215183813394,1.4271945957883734,1.6275159466122078,1.69263057727874,-0.43794554085718024,2.2936167157241867,1.5060072044287904,1.9247467241533158,2.971565848245718,2.3511047492659554,-0.5703108638932032,0.07390195373379957,1.2776071666564428
2,719
Abnormal retinal artery morphology
8
20
3.185237
0.001446
Q13510,P17900,P07602,P21964,P16278,P06865,P10619,P03886
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
35,135,168,171,206,177,89,26
1017,1108,26,177,168,1818,89,1821,206,135,171,1161,2185,2215,35,1804,1064,265,1520,803
0.05913077172037472,-0.015378603154741318,3.105839691433299,1.6275159466122078,1.69263057727874,-0.43794554085718024,2.2936167157241867,-0.43794554085718024,1.5060072044287904,1.9247467241533158,1.6710149037139495,-0.04549245437206825,-0.6548601180580003,-0.6719437646434965,2.971565848245718,-0.421643782078971,0.029458532651360454,1.2776071666564428,-0.24574059272730153,0.26211431465637414
2,719
Organic anion transport
18
34
3.177215
0.001487
O60831,O75915,Q9UJS0,Q9UBX3,O75746,P07602,Q9NZJ7,P05141,Q9H2D1,Q6NUK1,P12236,Q8TB61,Q9H9B4,Q96QD8,Q9BQT8,P12235,Q08722,Q9Y619
Processes and pathways
GO Biological process
msigdb_gobp
95,383,262,38,449,168,265,327,13,299,143,78,334,147,311,186,188,125
2040,600,95,449,383,2122,327,1650,168,806,186,143,1355,740,1385,781,823,471,677,188,759,864,299,2337,78,646,147,311,13,334,265,38,262,125
-0.5703108638932032,0.49819048944279026,2.22575796347679,0.736834876495512,0.8774087768247075,-0.620867881511793,1.0631453851685053,-0.3409219722772057,1.69263057727874,0.2478813025768698,1.605631086088607,1.8832934520415403,-0.1677772467277911,0.3186519434677123,-0.18327357472878134,0.2763076509973368,0.23360837776605786,0.6978221404482146,0.402300331182603,1.605631086088607,0.30457623372576403,0.1905477242530135,1.1595533384376537,-0.7932038385838693,2.379619278698563,0.44361639063605623,1.8728793126258834,1.1356182999373312,3.4433864453496845,1.038761445699194,1.2776071666564428,2.911763976530236,1.289267000376432,1.965878763574573
2,719
Mitochondrial membrane organization
18
45
3.174619
0.0015
O95202,P05141,Q13505,Q15070,Q9NS69,P62072,Q9P0J0,Q9NX63,Q9Y5Z4,O14737,O60313,P52789,Q9BUR5,Q16891,P45880,Q9H3K2,P12235,Q5XKP0
Processes and pathways
GO Biological process
msigdb_gobp
326,327,105,141,11,10,204,367,236,368,209,278,179,404,22,247,186,155
2147,368,209,1090,628,941,326,1795,327,1133,712,1036,186,1485,1356,2076,2279,2501,22,432,278,10,1391,105,141,1780,404,714,1393,155,1061,865,1494,179,247,11,721,367,204,998,1235,1316,502,2672,236
-0.6378349653375106,0.9400635335930252,1.494820444712504,-0.00038868636313022414,0.457314566306333,0.11795895191442474,1.0631453851685053,-0.421643782078971,1.0631453851685053,-0.030413098045804464,0.34668734253092304,0.04431638803769443,1.605631086088607,-0.23005094416154934,-0.1677772467277911,-0.587106244130671,-0.7235499894095512,-0.9899664782882975,3.253054371219224,0.7755544905767453,1.2424706616319041,3.4899576845407503,-0.18327357472878134,2.1865914316960353,1.9040605759318283,-0.4053949717396913,0.8394483821163174,0.34668734253092304,-0.18327357472878134,1.7782191520986066,0.029458532651360454,0.1905477242530135,-0.23005094416154934,1.6275159466122078,1.3586851022140123,3.474477642713755,0.34668734253092304,0.9525040135933169,1.5394252878937733,0.08863020155351369,-0.09100256702323781,-0.13692690238543065,0.6453409341751739,-1.5704713475646683,1.3930518398628324
2,719
Anion transmembrane transporter activity
20
36
3.168566
0.001532
Q15043,Q9UJS0,P51790,O43681,P21796,Q9H2D1,P12236,Q9Y277,Q96QD8,P45880,Q9UBX3,Q6NUK1,Q9C0H2,Q9BQT8,P12235,O75746,P05141,Q8TB61,Q9H9B4,Q9Y619
Functions
GO Molecular function
msigdb_gomf
386,262,261,389,12,13,143,146,147,22,38,299,49,311,186,449,327,78,334,125
2067,2040,389,600,449,327,806,186,143,12,1385,22,261,781,823,471,677,759,386,864,2542,299,2337,78,646,147,709,311,49,13,334,38,262,146,125,2608
-0.587106244130671,-0.5703108638932032,0.8647862588625002,0.49819048944279026,0.736834876495512,1.0631453851685053,0.2478813025768698,1.605631086088607,1.8832934520415403,3.451175716066335,-0.18327357472878134,3.253054371219224,1.289267000376432,0.2763076509973368,0.23360837776605786,0.6978221404482146,0.402300331182603,0.30457623372576403,0.8774087768247075,0.1905477242530135,-1.0635076502293486,1.1595533384376537,-0.7932038385838693,2.379619278698563,0.44361639063605623,1.8728793126258834,0.3606474828614861,1.1356182999373312,2.763729779838205,3.4433864453496845,1.038761445699194,2.911763976530236,1.289267000376432,1.8832934520415403,1.965878763574573,-1.213975141317416
2,719
Calcium signaling pathway
7
13
3.1681
0.001534
P46020,P21796,P20020,P12236,Q9Y277,P45880,P12235
Processes and pathways
KEGG Pathways
msigdb_kegg
296,12,170,143,146,22,186
327,1036,186,143,547,1627,170,12,22,296,1040,1178,146
1.0631453851685053,0.04431638803769443,1.605631086088607,1.8832934520415403,0.5656005771908399,-0.32493250526949763,1.6710149037139495,3.451175716066335,3.253054371219224,1.1714797320050525,0.04431638803769443,-0.04549245437206825,1.8832934520415403
2,719
Sphingolipid biosynthetic process
7
15
3.121913
0.001797
Q06136,Q13510,O15269,P04062,Q96G23,Q16739,O95470
Processes and pathways
GO Biological process
msigdb_gobp
65,35,260,71,45,83,93
260,1070,93,71,2251,672,65,35,83,1393,45,679,1014,302,1404
1.289267000376432,0.014556932935040613,2.245234151230295,2.5107215183813394,-0.7062882632563935,0.402300331182603,2.5750940135788953,2.971565848245718,2.3511047492659554,-0.18327357472878134,2.798926517414969,0.402300331182603,0.07390195373379957,1.1595533384376537,-0.18327357472878134
2,719
Organic anion transmembrane transporter activity
11
24
3.080236
0.002068
Q9UJS0,Q9UBX3,P05141,Q9H2D1,Q6NUK1,P12236,Q8TB61,Q96QD8,Q9BQT8,P12235,Q9Y619
Functions
GO Molecular function
msigdb_gomf
262,38,327,13,299,143,78,147,311,186,125
2040,600,449,327,806,186,143,1385,781,823,677,759,864,299,2337,78,646,147,311,13,334,38,262,125
-0.5703108638932032,0.49819048944279026,0.736834876495512,1.0631453851685053,0.2478813025768698,1.605631086088607,1.8832934520415403,-0.18327357472878134,0.2763076509973368,0.23360837776605786,0.402300331182603,0.30457623372576403,0.1905477242530135,1.1595533384376537,-0.7932038385838693,2.379619278698563,0.44361639063605623,1.8728793126258834,1.1356182999373312,3.4433864453496845,1.038761445699194,2.911763976530236,1.289267000376432,1.965878763574573
2,719
Transporter activity
71
146
3.072424
0.002123
Q15043,Q9UJS0,Q99595,P17900,P51790,Q9Y487,Q8NHS3,Q9NS69,P21796,Q9H2D1,Q9UDW1,O43676,P38435,P12236,Q9Y277,O60830,Q96QD8,O15118,P45880,Q9BZF1,Q93050,P03886,P13073,P47985,O75964,Q9UBX3,P05023,Q5T1Q4,P20020,Q96ES6,Q6NUK1,O96000,Q9C0H2,P00403,Q9BQT8,O14925,P12235,O43772,P61916,Q03518,P08183,O43681,O75746,Q96H78,P04062,O95202,Q99797,P05141,Q9P0J0,Q70HW3,Q8IXU6,Q8TB61,Q9UGP8,Q9H9B4,P56385,Q6P4A7,Q9Y5K8,Q14849,Q15388,P61421,Q9BSK2,P24539,O15173,Q8WTV0,Q7KZN9,O75306,Q07820,Q9HD20,L0R6Q1,Q6P4Q7,Q9Y619
Functions
GO Molecular function
msigdb_gomf
386,262,6,135,261,395,270,11,12,13,14,15,139,143,146,19,147,273,22,281,401,26,286,408,34,38,295,169,170,300,299,426,49,305,311,54,186,437,446,447,322,389,449,70,71,326,201,327,204,76,461,78,79,334,336,210,341,87,219,348,221,98,107,110,364,244,377,120,375,122,125
375,2067,856,2040,54,273,107,15,389,437,600,19,727,872,244,1924,449,804,34,628,858,1289,326,1598,426,609,305,26,71,295,327,751,2071,2103,322,806,1006,1291,186,143,286,547,135,2225,170,504,877,2404,12,2251,98,2476,740,2693,807,794,515,139,2182,1385,22,408,2520,753,495,2559,261,769,810,1200,781,823,471,852,336,348,1715,446,566,1366,2132,677,447,1391,377,1304,2601,759,883,87,386,219,864,1057,1307,169,2542,299,2337,210,122,76,364,746,461,866,989,270,78,110,2454,401,844,300,70,646,147,709,1396,1563,6,201,1752,311,221,1256,1343,281,49,13,334,120,2671,11,204,38,14,79,973,262,777,146,395,341,125,2608
0.9025617730365805,-0.587106244130671,0.1905477242530135,-0.5703108638932032,2.6657421041309006,1.2542091223510612,2.1767547750820517,3.4199522827989974,0.8647862588625002,0.7626802321711698,0.49819048944279026,3.317234140715181,0.332688904231155,0.17611273471205496,1.3586851022140123,-0.5036894974780469,0.736834876495512,0.2478813025768698,2.971565848245718,0.457314566306333,0.1905477242530135,-0.13692690238543065,1.0631453851685053,-0.3089938532666943,0.78839669765801,0.4846014092491796,1.147599572470142,3.105839691433299,2.5107215183813394,1.1714797320050525,1.0631453851685053,0.30457623372576403,-0.587106244130671,-0.6039584463179856,1.087415425314427,0.2478813025768698,0.07390195373379957,-0.13692690238543065,1.605631086088607,1.8832934520415403,1.2189142308211247,0.5656005771908399,1.9247467241533158,-0.6890863348428883,1.6710149037139495,0.632136528586786,0.17611273471205496,-0.8638509468356808,3.451175716066335,-0.7062882632563935,2.215993204297903,-0.9536034576855446,0.3186519434677123,-2.0224789299810415,0.2478813025768698,0.26211431465637414,0.6188981125431084,1.9040605759318283,-0.6548601180580003,-0.18327357472878134,3.253054371219224,0.826732699034428,-1.0265997707300218,0.30457623372576403,0.6453409341751739,-1.1006945383567346,1.289267000376432,0.29046154644551864,0.2478813025768698,-0.07578689853775272,0.2763076509973368,0.23360837776605786,0.6978221404482146,0.20494183108481331,1.0265264066984594,0.9896472724402028,-0.37305474027032975,0.7497737515679389,0.5387428051993683,-0.1677772467277911,-0.620867881511793,0.402300331182603,0.7497737515679389,-0.18327357472878134,0.9025617730365805,-0.13692690238543065,-1.213975141317416,0.30457623372576403,0.17611273471205496,2.3128479941750375,0.8774087768247075,1.4611164567099202,0.1905477242530135,0.029458532651360454,-0.13692690238543065,1.6818338097384962,-1.0635076502293486,1.1595533384376537,-0.7932038385838693,1.494820444712504,1.98632596881489,2.436197942025277,0.9525040135933169,0.3186519434677123,0.7108592467728196,0.1905477242530135,0.08863020155351369,1.2659212488513751,2.379619278698563,2.1471356130946906,-0.9175064966386184,0.8521328477933847,0.2192953010576298,1.1595533384376537,2.5199648159717087,0.44361639063605623,1.8728793126258834,0.3606474828614861,-0.18327357472878134,-0.2772676267666931,3.7466882849921066,1.5615865779228295,-0.38919874485326694,1.1356182999373312,1.4498335257671533,-0.10626425831084813,-0.15232845914399104,1.2424706616319041,2.763729779838205,3.4433864453496845,1.038761445699194,2.0066948267496136,-1.5704713475646683,3.474477642713755,1.5394252878937733,2.911763976530236,3.427774762153474,2.379619278698563,0.10331578012873843,1.289267000376432,0.29046154644551864,1.8832934520415403,0.8647862588625002,1.0265264066984594,1.965878763574573,-1.213975141317416
2,719
Membrane lipid biosynthetic process
8
21
3.065505
0.002173
Q06136,Q13510,O15269,P04062,Q96G23,Q16739,O43292,O95470
Processes and pathways
GO Biological process
msigdb_gobp
65,35,260,71,45,83,248,93
260,1070,248,682,93,71,2251,672,65,35,83,1393,429,688,1698,45,1281,679,1014,302,1404
1.289267000376432,0.014556932935040613,1.3471792062317862,0.38845375763582707,2.245234151230295,2.5107215183813394,-0.7062882632563935,0.402300331182603,2.5750940135788953,2.971565848245718,2.3511047492659554,-0.18327357472878134,0.78839669765801,0.38845375763582707,-0.3569626006240997,2.798926517414969,-0.12157226993528147,0.402300331182603,0.07390195373379957,1.1595533384376537,-0.18327357472878134
2,719
Endoplasmic reticulum golgi intermediate compartment membrane
15
22
3.057351
0.002233
Q10472,Q12907,Q9Y282,P51572,Q969X5,Q15363,P24390,Q9Y3B3,O15260,Q9H0U4,Q15904,Q8N511,P49257,P49755,Q03518
Localization
GO Cellular component
msigdb_gocc
224,418,2,385,392,69,9,202,330,366,240,48,470,495,447
330,1622,1004,9,2367,470,495,385,1244,447,224,418,69,240,48,392,932,2528,366,2,562,202
1.0509677239800752,-0.32493250526949763,0.07390195373379957,3.672408462929854,-0.8284013522129561,0.6978221404482146,0.6453409341751739,0.8774087768247075,-0.10626425831084813,0.7497737515679389,1.4385262761005175,0.8139856344410125,2.5199648159717087,1.3701657615426401,2.763729779838205,0.8647862588625002,0.13255997690276794,-1.0265997707300218,0.9525040135933169,4.013195205240466,0.552189269880853,1.5505176058047423
2,719
Organic acid transmembrane transport
12
24
3.053798
0.00226
O60831,O75915,P08183,Q9UJS0,Q9UBX3,O75746,Q9H2D1,Q9H9B4,Q96QD8,Q9BQT8,O43772,Q9Y619
Processes and pathways
GO Biological process
msigdb_gobp
95,383,322,262,38,449,13,334,147,311,437,125
437,95,449,383,1650,322,806,478,740,1111,1385,629,781,823,677,864,646,147,311,13,334,38,262,125
0.7626802321711698,2.22575796347679,0.736834876495512,0.8774087768247075,-0.3409219722772057,1.087415425314427,0.2478813025768698,0.6847519362737263,0.3186519434677123,-0.015378603154741318,-0.18327357472878134,0.457314566306333,0.2763076509973368,0.23360837776605786,0.402300331182603,0.1905477242530135,0.44361639063605623,1.8728793126258834,1.1356182999373312,3.4433864453496845,1.038761445699194,2.911763976530236,1.289267000376432,1.965878763574573
2,719
Carbohydrate derivative transport
10
13
3.051399
0.002278
P05141,P07602,Q9NZJ7,Q8TB61,Q6NUK1,P12236,Q8WTV0,L0R6Q1,P12235,Q08722
Processes and pathways
GO Biological process
msigdb_gobp
327,168,265,78,299,143,110,375,186,188
375,600,327,168,186,143,1385,446,188,299,78,110,265
0.9025617730365805,0.49819048944279026,1.0631453851685053,1.69263057727874,1.605631086088607,1.8832934520415403,-0.18327357472878134,0.7497737515679389,1.605631086088607,1.1595533384376537,2.379619278698563,2.1471356130946906,1.2776071666564428
2,719
Protein localization
30
68
2.991478
0.002776
Q9UJS0,Q99595,O15254,P62072,O43681,P21796,Q9NS69,P12236,Q13011,O60830,P50402,Q10713,O75381,P09601,Q9BY49,Q5JRX3,O14925,P12235,P40855,P46379,P51648,O75746,Q15388,O00116,Q8N4H5,Q13505,Q9NX63,Q9Y512,O43615,Q9NR77
Processes and pathways
Reactome Pathways
msigdb_reactome
262,6,510,10,389,12,11,143,526,19,403,540,417,40,561,53,54,186,317,191,64,449,219,218,104,105,367,502,379,253
218,778,54,510,379,389,1002,600,19,417,2545,1090,1265,1963,449,1215,628,609,751,1006,2580,40,2430,186,143,1931,12,1137,2476,740,1020,2279,317,191,403,64,851,1462,10,1802,540,526,105,558,219,714,53,2699,104,866,948,2061,6,2578,1588,561,1401,253,11,367,1404,2457,262,1235,2066,830,502,2672
1.4611164567099202,0.2763076509973368,2.6657421041309006,0.6188981125431084,0.8900005618991303,0.8647862588625002,0.07390195373379957,0.49819048944279026,3.317234140715181,0.8139856344410125,-1.082065937615682,-0.00038868636313022414,-0.12157226993528147,-0.5202616114390414,0.736834876495512,-0.09100256702323781,0.457314566306333,0.4846014092491796,0.30457623372576403,0.07390195373379957,-1.1570079553072803,2.859976400730297,-0.8995564994467704,1.605631086088607,1.8832934520415403,-0.5036894974780469,3.451175716066335,-0.030413098045804464,-0.9536034576855446,0.3186519434677123,0.05913077172037472,-0.7235499894095512,1.111572693459288,1.594654460100512,0.8394483821163174,2.5750940135788953,0.20494183108481331,-0.2144101059765268,3.4899576845407503,-0.421643782078971,0.5923184989479339,0.6056254989038173,2.1865914316960353,0.552189269880853,1.4611164567099202,0.34668734253092304,2.701579665755794,-2.2773891393535837,2.1964100084149285,0.1905477242530135,0.11795895191442474,-0.5703108638932032,3.7466882849921066,-1.138164966594554,-0.2931056735100328,0.552189269880853,-0.18327357472878134,1.3125089094881686,3.474477642713755,0.9525040135933169,-0.18327357472878134,-0.9175064966386184,1.289267000376432,-0.09100256702323781,-0.5703108638932032,0.23360837776605786,0.6453409341751739,-1.5704713475646683
2,719
Sensory perception of light stimulus
7
14
2.976376
0.002917
O76024,Q99797,O60313,O43924,P50897,Q6P4Q7,Q15555
Processes and pathways
GO Biological process
msigdb_gobp
167,201,209,21,24,122,157
21,209,167,1929,1321,24,1610,410,157,122,2307,201,225,1449
3.293254641370149,1.494820444712504,1.69263057727874,-0.5036894974780469,-0.15232845914399104,3.1471316821409943,-0.3089938532666943,0.826732699034428,1.7675960795947097,1.98632596881489,-0.7582546181179882,1.5615865779228295,1.4385262761005175,-0.19881775585569805
2,719
Protein transporter activity
6
13
2.968881
0.002989
Q99595,Q9NS69,Q9UGP8,O60830,O14925,Q9HD20
Functions
GO Molecular function
msigdb_gomf
6,11,79,19,54,120
54,19,628,609,495,1715,377,219,866,6,120,11,79
2.6657421041309006,3.317234140715181,0.457314566306333,0.4846014092491796,0.6453409341751739,-0.37305474027032975,0.9025617730365805,1.4611164567099202,0.1905477242530135,3.7466882849921066,2.0066948267496136,3.474477642713755,2.379619278698563
2,719
Lytic vacuole organization
9
19
2.964598
0.003031
Q14108,O14773,P04062,P54802,O75503,Q8NHS3,Q8N511,P11117,P50897
Processes and pathways
GO Biological process
msigdb_gobp
193,134,71,264,231,270,48,275,24
2147,134,231,71,1818,380,275,913,24,1297,264,1364,927,193,915,48,270,644,2165
-0.6378349653375106,1.9247467241533158,1.404457491582026,2.5107215183813394,-0.43794554085718024,0.8900005618991303,1.2424706616319041,0.1471191126541989,3.1471316821409943,-0.13692690238543065,1.2776071666564428,-0.1677772467277911,0.13255997690276794,1.5836549017230799,0.1471191126541989,2.763729779838205,1.2659212488513751,0.44361639063605623,-0.6378349653375106
2,719
Sphingolipid metabolism
8
10
2.932379
0.003364
Q06136,Q13510,Q9NZ01,P04062,P07602,P17900,Q16739,O95470
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
65,35,230,71,168,135,83,93
260,1070,93,71,168,135,65,35,83,230
1.289267000376432,0.014556932935040613,2.245234151230295,2.5107215183813394,1.69263057727874,1.9247467241533158,2.5750940135788953,2.971565848245718,2.3511047492659554,1.4271945957883734
2,719
Endopeptidase activity
24
56
2.930103
0.003388
O14773,P28072,P28074,P20618,P67812,P49720,Q9BYT8,Q5JRX3,Q92542,P49721,Q99797,Q9UPU5,O75844,Q8TCT8,P28070,P52888,Q96K76,Q8TCT9,P42892,Q13043,O43292,P07384,P51784,Q9NZ08
Functions
GO Molecular function
msigdb_gomf
134,138,523,149,152,282,180,53,453,67,201,81,82,212,469,100,487,498,239,372,248,249,381,254
134,248,563,894,1265,82,249,1766,1931,2402,149,638,2226,469,138,523,1458,2349,1268,239,2255,960,282,67,381,100,1244,2352,630,152,540,372,2541,641,2002,2683,1491,53,697,2087,212,498,453,688,801,2061,1951,487,889,1340,201,1752,180,254,81,1316
1.9247467241533158,1.3471792062317862,0.5387428051993683,0.16163661432793977,-0.12157226993528147,2.3511047492659554,1.3471792062317862,-0.4053949717396913,-0.5036894974780469,-0.8638509468356808,1.8624446742934746,0.44361639063605623,-0.6890863348428883,0.6978221404482146,1.9040605759318283,0.6056254989038173,-0.2144101059765268,-0.8107713240707701,-0.12157226993528147,1.3701657615426401,-0.7062882632563935,0.10331578012873843,1.2307057402478268,2.5475999117636636,0.8900005618991303,2.2062105758767268,-0.10626425831084813,-0.8107713240707701,0.457314566306333,1.8310169016228028,0.5923184989479339,0.9275931030431922,-1.0635076502293486,0.44361639063605623,-0.5368889474821656,-1.7590293673389303,-0.23005094416154934,2.701579665755794,0.37456954772114676,-0.587106244130671,1.483609806203434,0.6453409341751739,0.736834876495512,0.38845375763582707,0.26211431465637414,-0.5703108638932032,-0.5036894974780469,0.671648454750572,0.17611273471205496,-0.15232845914399104,1.5615865779228295,-0.38919874485326694,1.6275159466122078,1.3125089094881686,2.3606264414766716,-0.13692690238543065
2,719
primary active transporter
13
18
2.925384
0.00344
O75381,O60888,P05023,Q8N4H5,P16615,Q9NS69,O96008,Q9H9B4,P20020,Q6P4A7,Q9BUN8,O94826,Q15388
Functions
Panther Protein class
panther_protein_class
417,292,295,104,547,11,609,334,170,210,116,628,219
292,417,628,609,295,1765,547,170,1114,219,864,210,104,646,116,334,1401,11
1.1833788863385122,0.8139856344410125,0.457314566306333,0.4846014092491796,1.1714797320050525,-0.4053949717396913,0.5656005771908399,1.6710149037139495,-0.015378603154741318,1.4611164567099202,0.1905477242530135,1.494820444712504,2.1964100084149285,0.44361639063605623,2.087399401896311,1.038761445699194,-0.18327357472878134,3.474477642713755
2,719
Ion transport
18
44
2.912769
0.003582
Q15043,P24539,O75964,P51790,P05023,Q9Y487,O95202,P21796,P20020,Q15904,P56385,Q9C0H2,Q9Y277,Q96QD8,Q9Y5K8,P45880,Q6P4Q7,P61421
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
386,98,34,261,295,395,326,12,170,240,336,49,146,147,341,22,122,348
2067,804,34,326,609,295,751,547,170,877,2404,12,98,2476,794,515,2182,22,2520,261,1114,471,852,336,348,883,386,240,2542,122,989,401,844,147,709,1230,1256,49,594,973,146,395,341,2608
-0.587106244130671,0.2478813025768698,2.971565848245718,1.0631453851685053,0.4846014092491796,1.1714797320050525,0.30457623372576403,0.5656005771908399,1.6710149037139495,0.17611273471205496,-0.8638509468356808,3.451175716066335,2.215993204297903,-0.9536034576855446,0.26211431465637414,0.6188981125431084,-0.6548601180580003,3.253054371219224,-1.0265997707300218,1.289267000376432,-0.015378603154741318,0.6978221404482146,0.20494183108481331,1.0265264066984594,0.9896472724402028,0.17611273471205496,0.8774087768247075,1.3701657615426401,-1.0635076502293486,1.98632596881489,0.08863020155351369,0.8521328477933847,0.2192953010576298,1.8728793126258834,0.3606474828614861,-0.09100256702323781,-0.10626425831084813,2.763729779838205,0.5117436144293259,0.10331578012873843,1.8832934520415403,0.8647862588625002,1.0265264066984594,-1.213975141317416
2,719
Receptor
14
32
2.898667
0.003748
Q14108,P02786,Q99720,P35613,P24390,Q9NS69,O15173,Q99523,Q8WTV0,Q14739,O00264,O15118,Q9Y5M8,O15031
Functions
Protein Atlas Molecular function
protein_atlas_molecular_function
193,450,36,263,9,11,107,365,110,207,335,273,119,376
335,376,273,107,450,1650,1072,1989,1848,1681,1682,1292,956,1931,467,9,263,1466,1274,193,207,864,2084,110,707,2454,365,593,36,11,1406,119
1.0265264066984594,0.9025617730365805,1.2542091223510612,2.1767547750820517,0.736834876495512,-0.3409219722772057,0.014556932935040613,-0.5368889474821656,-0.4543006169521521,-0.3569626006240997,-0.3569626006240997,-0.13692690238543065,0.10331578012873843,-0.5036894974780469,0.6978221404482146,3.672408462929854,1.2776071666564428,-0.2144101059765268,-0.12157226993528147,1.5836549017230799,1.5060072044287904,0.1905477242530135,-0.587106244130671,2.1471356130946906,0.3606474828614861,-0.9175064966386184,0.9525040135933169,0.5117436144293259,2.946016924906694,3.474477642713755,-0.18327357472878134,2.037102603070871
2,719
Mitochondrial protein import
12
33
2.882948
0.00394
Q99595,Q8N4H5,Q15388,P62072,Q9NS69,P21796,Q13505,P12236,O60830,Q5JRX3,O14925,P12235
Processes and pathways
Reactome Pathways
msigdb_reactome
6,104,219,10,11,12,105,143,19,53,54,186
54,379,19,2545,1090,1265,449,628,609,751,1006,2430,186,143,12,2476,2279,10,540,105,219,714,53,104,6,2578,1401,11,367,262,1235,502,2672
2.6657421041309006,0.8900005618991303,3.317234140715181,-1.082065937615682,-0.00038868636313022414,-0.12157226993528147,0.736834876495512,0.457314566306333,0.4846014092491796,0.30457623372576403,0.07390195373379957,-0.8995564994467704,1.605631086088607,1.8832934520415403,3.451175716066335,-0.9536034576855446,-0.7235499894095512,3.4899576845407503,0.5923184989479339,2.1865914316960353,1.4611164567099202,0.34668734253092304,2.701579665755794,2.1964100084149285,3.7466882849921066,-1.138164966594554,-0.18327357472878134,3.474477642713755,0.9525040135933169,1.289267000376432,-0.09100256702323781,0.6453409341751739,-1.5704713475646683
2,719
Sphingolipid metabolism
7
11
2.879989
0.003977
Q06136,Q13510,P06280,P04062,P16278,Q16739,O95470
Processes and pathways
KEGG Pathways
msigdb_kegg
65,35,226,71,206,83,93
260,1070,389,93,71,226,206,65,35,83,1014
1.289267000376432,0.014556932935040613,0.8647862588625002,2.245234151230295,2.5107215183813394,1.4271945957883734,1.5060072044287904,2.5750940135788953,2.971565848245718,2.3511047492659554,0.07390195373379957
2,719
Protein transmembrane transport
12
23
2.877863
0.004004
Q15629,O75381,Q99595,Q9NS69,O75298,Q9UGP8,O60830,Q07820,O14925,O95831,Q15388,O43615
Processes and pathways
GO Biological process
msigdb_gobp
96,417,6,11,303,79,19,377,54,465,219,379
54,379,19,303,417,628,465,609,2430,495,1462,2156,1715,377,219,96,714,2114,1282,6,1401,11,79
2.6657421041309006,0.8900005618991303,3.317234140715181,1.147599572470142,0.8139856344410125,0.457314566306333,0.6978221404482146,0.4846014092491796,-0.8995564994467704,0.6453409341751739,-0.2144101059765268,-0.6378349653375106,-0.37305474027032975,0.9025617730365805,1.4611164567099202,2.22575796347679,0.34668734253092304,-0.6039584463179856,-0.12157226993528147,3.7466882849921066,-0.18327357472878134,3.474477642713755,2.379619278698563
2,719
Protein targeting to mitochondrion
20
41
2.872101
0.004078
Q9Y371,P51572,Q99595,P62072,Q9NS69,O60830,P49840,Q5JRX3,O14925,Q99797,Q9P0J0,Q9UBE0,P49257,O95831,Q15388,Q8N4H5,P55786,Q9Y512,O14737,O43615
Processes and pathways
GO Biological process
msigdb_gobp
520,385,6,10,11,19,432,53,54,201,204,340,470,465,219,104,491,502,368,379
1621,368,54,563,379,19,1265,628,941,465,609,1133,2430,1896,2076,470,432,385,491,10,2111,540,219,2232,714,1393,53,2292,104,948,6,201,1401,11,204,340,998,520,830,502,2672
-0.32493250526949763,0.9400635335930252,2.6657421041309006,0.5387428051993683,0.8900005618991303,3.317234140715181,-0.12157226993528147,0.457314566306333,0.11795895191442474,0.6978221404482146,0.4846014092491796,-0.030413098045804464,-0.8995564994467704,-0.48717221640031005,-0.587106244130671,0.6978221404482146,0.7755544905767453,0.8774087768247075,0.6585115148857332,3.4899576845407503,-0.6039584463179856,0.5923184989479339,1.4611164567099202,-0.6890863348428883,0.34668734253092304,-0.18327357472878134,2.701579665755794,-0.7408719578287188,2.1964100084149285,0.11795895191442474,3.7466882849921066,1.5615865779228295,-0.18327357472878134,3.474477642713755,1.5394252878937733,1.0265264066984594,0.08863020155351369,0.6188981125431084,0.23360837776605786,0.6453409341751739,-1.5704713475646683
2,719
Corneal opacity
15
42
2.833168
0.004609
Q06136,Q13510,O43505,O96028,O95202,P53701,P04062,P06280,O75845,Q6NUK1,P16278,O75844,P10619,P40855,P51648
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
65,35,195,166,326,199,71,226,203,299,206,82,89,317,64
1705,195,2101,1108,2557,417,82,203,1597,326,166,1354,71,1034,226,2045,89,206,1196,1020,1161,317,64,2109,199,548,2215,1039,2700,65,1578,35,1804,1556,2306,299,339,608,1672,1520,1048,803
-0.37305474027032975,1.5726323086619758,-0.6039584463179856,-0.015378603154741318,-1.1006945383567346,0.8139856344410125,2.3511047492659554,1.5394252878937733,-0.3089938532666943,1.0631453851685053,1.7034053026076874,-0.1677772467277911,2.5107215183813394,0.04431638803769443,1.4271945957883734,-0.5703108638932032,2.2936167157241867,1.5060072044287904,-0.07578689853775272,0.05913077172037472,-0.04549245437206825,1.111572693459288,2.5750940135788953,-0.6039584463179856,1.5615865779228295,0.5656005771908399,-0.6719437646434965,0.04431638803769443,-2.301252570488206,2.5750940135788953,-0.2931056735100328,2.971565848245718,-0.421643782078971,-0.2772676267666931,-0.7582546181179882,1.1595533384376537,1.0265264066984594,0.49819048944279026,-0.3409219722772057,-0.24574059272730153,0.04431638803769443,0.26211431465637414
2,719
Mitochondrial respiratory chain complex assembly
15
32
2.831022
0.00464
Q69YU5,Q96CU9,Q15070,Q9P0J0,O96000,O43676,Q9Y512,Q9BRT2,O75306,Q6DKK2,O95831,P03886,Q9H061,Q9BSK2,P47985
Processes and pathways
GO Biological process
msigdb_gobp
131,39,141,204,426,15,502,406,244,118,465,26,27,221,408
15,511,872,244,1924,651,858,1598,465,426,26,2693,408,769,676,141,1057,1307,131,118,39,406,1151,221,890,27,1956,608,1175,204,1235,502
3.4199522827989974,0.6188981125431084,0.17611273471205496,1.3586851022140123,-0.5036894974780469,0.4298814338746595,0.1905477242530135,-0.3089938532666943,0.6978221404482146,0.78839669765801,3.105839691433299,-2.0224789299810415,0.826732699034428,0.29046154644551864,0.402300331182603,1.9040605759318283,0.029458532651360454,-0.13692690238543065,1.9350596419712964,2.04720003960902,2.894556239112553,0.8394483821163174,-0.030413098045804464,1.4498335257671533,0.17611273471205496,3.0892351012046553,-0.5036894974780469,0.49819048944279026,-0.04549245437206825,1.5394252878937733,-0.09100256702323781,0.6453409341751739
2,719
Dementia
24
50
2.816897
0.004849
P36543,P17900,Q9Y487,Q9NZJ7,O43681,O15118,P35637,P03886,Q06787,Q13510,O76024,P07602,P54886,P06865,P00403,Q14203,P21912,P61916,O43464,Q14108,P04062,O60313,P22626,O96008
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
515,135,395,265,389,273,276,26,409,35,167,168,548,177,305,568,444,446,563,193,71,209,468,609
1180,273,563,389,209,167,609,305,26,71,954,610,177,168,942,2510,135,1007,444,468,1037,672,1714,276,515,2182,1459,1074,2130,548,2228,446,1635,2409,409,1223,35,193,568,1721,1334,1012,1170,2341,2165,2470,265,736,870,395
-0.0606169582349026,1.2542091223510612,0.5387428051993683,0.8647862588625002,1.494820444712504,1.69263057727874,0.4846014092491796,1.147599572470142,3.105839691433299,2.5107215183813394,0.10331578012873843,0.4846014092491796,1.6275159466122078,1.69263057727874,0.11795895191442474,-1.008249073280028,1.9247467241533158,0.07390195373379957,0.7497737515679389,0.6978221404482146,0.04431638803769443,0.402300331182603,-0.37305474027032975,1.2424706616319041,0.6188981125431084,-0.6548601180580003,-0.2144101059765268,0.014556932935040613,-0.620867881511793,0.5656005771908399,-0.6890863348428883,0.7497737515679389,-0.32493250526949763,-0.8638509468356808,0.826732699034428,-0.09100256702323781,2.971565848245718,1.5836549017230799,0.5387428051993683,-0.37305474027032975,-0.15232845914399104,0.07390195373379957,-0.04549245437206825,-0.7932038385838693,-0.6378349653375106,-0.9355219790549657,1.2776071666564428,0.332688904231155,0.1905477242530135,0.8647862588625002
2,719
Ion channel transport
13
23
2.808821
0.004972
P36543,Q99576,P51790,P05023,Q9Y487,P20020,Q15904,Q93050,Q9C0H2,Q96PU5,Q9Y5K8,Q9HD20,P61421
Processes and pathways
Reactome Pathways
msigdb_reactome
515,324,261,295,395,170,240,401,49,474,341,120,348
295,547,170,877,2404,1604,515,2182,261,1114,348,1273,1743,240,401,474,324,49,1400,120,973,395,341
1.1714797320050525,0.5656005771908399,1.6710149037139495,0.17611273471205496,-0.8638509468356808,-0.3089938532666943,0.6188981125431084,-0.6548601180580003,1.289267000376432,-0.015378603154741318,0.9896472724402028,-0.12157226993528147,-0.38919874485326694,1.3701657615426401,0.8521328477933847,0.6978221404482146,1.0752945717970073,2.763729779838205,-0.18327357472878134,2.0066948267496136,0.10331578012873843,0.8647862588625002,1.0265264066984594
2,719
Membrane lipid catabolic process
6
11
2.806402
0.00501
Q13510,P17900,P04062,P06865,P50897,O95470
Processes and pathways
GO Biological process
msigdb_gobp
35,135,71,177,24,93
93,71,1034,226,177,1818,135,24,35,420,1014
2.245234151230295,2.5107215183813394,0.04431638803769443,1.4271945957883734,1.6275159466122078,-0.43794554085718024,1.9247467241533158,3.1471316821409943,2.971565848245718,0.8139856344410125,0.07390195373379957
2,719
Glycosaminoglycan metabolism
6
11
2.805306
0.005027
O43505,P54802,P16278,Q8TB61,P06865,Q8NCH0
Processes and pathways
Reactome Pathways
msigdb_reactome
195,264,206,78,177,56
922,195,267,177,1818,822,206,264,56,78,1178
0.13255997690276794,1.5726323086619758,1.2659212488513751,1.6275159466122078,-0.43794554085718024,0.23360837776605786,1.5060072044287904,1.2776071666564428,2.6657421041309006,2.379619278698563,-0.04549245437206825
2,719
Biliary tract abnormality
11
24
2.791842
0.005241
Q14108,O96028,O95202,P09601,Q9NZJ7,P07602,P04062,Q96J02,Q14739,Q13043,Q5XKP0
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
193,166,326,40,265,168,71,301,207,372,155
389,326,166,1354,71,168,40,1355,2612,1268,851,540,372,1578,193,207,155,2061,301,1701,265,597,1235,546
0.8647862588625002,1.0631453851685053,1.7034053026076874,-0.1677772467277911,2.5107215183813394,1.69263057727874,2.859976400730297,-0.1677772467277911,-1.233112298811929,-0.12157226993528147,0.20494183108481331,0.5923184989479339,0.9275931030431922,-0.2931056735100328,1.5836549017230799,1.5060072044287904,1.7782191520986066,-0.5703108638932032,1.1595533384376537,-0.3569626006240997,1.2776071666564428,0.5117436144293259,-0.09100256702323781,0.5789769223558233
2,719
Proton transmembrane transporter activity
18
34
2.787653
0.005309
P24539,O75964,P51790,O95202,Q9Y487,P05141,Q96ES6,Q9UDW1,Q7KZN9,P56385,Q93050,P00403,Q9Y5K8,P20674,P12235,P61421,P13073,P47985
Functions
GO Molecular function
msigdb_gomf
98,34,261,326,395,327,300,14,364,336,401,305,341,504,186,348,286,408
804,34,326,305,327,751,1006,1291,186,286,504,877,2404,98,2476,807,794,515,2182,408,2520,261,852,336,348,566,1304,364,401,300,14,973,395,341
0.2478813025768698,2.971565848245718,1.0631453851685053,1.147599572470142,1.0631453851685053,0.30457623372576403,0.07390195373379957,-0.13692690238543065,1.605631086088607,1.2189142308211247,0.632136528586786,0.17611273471205496,-0.8638509468356808,2.215993204297903,-0.9536034576855446,0.2478813025768698,0.26211431465637414,0.6188981125431084,-0.6548601180580003,0.826732699034428,-1.0265997707300218,1.289267000376432,0.20494183108481331,1.0265264066984594,0.9896472724402028,0.5387428051993683,-0.13692690238543065,0.9525040135933169,0.8521328477933847,1.1595533384376537,3.427774762153474,0.10331578012873843,0.8647862588625002,1.0265264066984594
2,719
Carboxylic acid transport
12
26
2.772546
0.005562
O60831,O75915,Q9UJS0,Q9UBX3,O75746,P07602,Q9NZJ7,Q9H2D1,Q9H9B4,Q96QD8,Q9BQT8,Q9Y619
Processes and pathways
GO Biological process
msigdb_gobp
95,383,262,38,449,168,265,13,334,147,311,125
2040,95,449,383,2122,1650,168,806,1355,740,1385,781,823,471,677,864,2337,646,147,311,13,334,265,38,262,125
-0.5703108638932032,2.22575796347679,0.736834876495512,0.8774087768247075,-0.620867881511793,-0.3409219722772057,1.69263057727874,0.2478813025768698,-0.1677772467277911,0.3186519434677123,-0.18327357472878134,0.2763076509973368,0.23360837776605786,0.6978221404482146,0.402300331182603,0.1905477242530135,-0.7932038385838693,0.44361639063605623,1.8728793126258834,1.1356182999373312,3.4433864453496845,1.038761445699194,1.2776071666564428,2.911763976530236,1.289267000376432,1.965878763574573
2,719
Parkinsons disease
17
50
2.767223
0.005654
P24539,P05141,P12235,O14949,P14406,P21796,Q9UDW1,P12236,O43676,O96000,Q9Y277,P00403,O75306,P45880,P03886,P13073,P47985
Processes and pathways
KEGG Pathways
msigdb_kegg
98,327,186,72,73,12,14,143,15,426,146,305,244,22,26,286,408
856,72,563,15,872,244,1924,804,858,1289,1598,426,305,26,327,751,1006,1796,1291,186,143,286,73,2317,1602,2225,504,12,444,2475,638,98,2476,2693,1714,807,794,22,408,2520,2559,769,811,2111,1040,1057,1307,2470,14,146
0.1905477242530135,2.4828960163826035,0.5387428051993683,3.4199522827989974,0.17611273471205496,1.3586851022140123,-0.5036894974780469,0.2478813025768698,0.1905477242530135,-0.13692690238543065,-0.3089938532666943,0.78839669765801,1.147599572470142,3.105839691433299,1.0631453851685053,0.30457623372576403,0.07390195373379957,-0.421643782078971,-0.13692690238543065,1.605631086088607,1.8832934520415403,1.2189142308211247,2.4828960163826035,-0.7756984250375901,-0.3089938532666943,-0.6890863348428883,0.632136528586786,3.451175716066335,0.7497737515679389,-0.9536034576855446,0.44361639063605623,2.215993204297903,-0.9536034576855446,-2.0224789299810415,-0.37305474027032975,0.2478813025768698,0.26211431465637414,3.253054371219224,0.826732699034428,-1.0265997707300218,-1.1006945383567346,0.29046154644551864,0.2478813025768698,-0.6039584463179856,0.04431638803769443,0.029458532651360454,-0.13692690238543065,-0.9355219790549657,3.427774762153474,1.8832934520415403
2,719
Sterol binding
6
14
2.765243
0.005688
Q14108,O95772,P21796,O15118,P45880,Q14849
Functions
GO Molecular function
msigdb_gomf
193,233,12,273,22,87
273,1762,233,2103,12,2251,1137,22,446,193,87,1396,1343,281
1.2542091223510612,-0.4053949717396913,1.3930518398628324,-0.6039584463179856,3.451175716066335,-0.7062882632563935,-0.030413098045804464,3.253054371219224,0.7497737515679389,1.5836549017230799,2.3128479941750375,-0.18327357472878134,-0.15232845914399104,1.2424706616319041
2,719
Secondary active transmembrane transporter activity
9
18
2.751182
0.005938
Q15043,Q9UBX3,P51790,O95202,P05141,Q96ES6,P12236,Q96QD8,P12235
Functions
GO Molecular function
msigdb_gomf
386,38,261,326,327,300,143,147,186
326,327,806,186,143,1385,261,781,823,471,566,677,386,864,989,300,147,38
1.0631453851685053,1.0631453851685053,0.2478813025768698,1.605631086088607,1.8832934520415403,-0.18327357472878134,1.289267000376432,0.2763076509973368,0.23360837776605786,0.6978221404482146,0.5387428051993683,0.402300331182603,0.8774087768247075,0.1905477242530135,0.08863020155351369,1.1595533384376537,1.8728793126258834,2.911763976530236
2,719
Organic acid transmembrane transporter activity
8
19
2.748356
0.005989
P08183,Q9UJS0,Q9UBX3,Q96H78,Q9H2D1,Q96QD8,Q9BQT8,Q9Y619
Functions
GO Molecular function
msigdb_gomf
322,262,38,70,13,147,311,125
2040,449,322,806,1385,781,823,677,864,2337,70,646,147,311,13,334,38,262,125
-0.5703108638932032,0.736834876495512,1.087415425314427,0.2478813025768698,-0.18327357472878134,0.2763076509973368,0.23360837776605786,0.402300331182603,0.1905477242530135,-0.7932038385838693,2.5199648159717087,0.44361639063605623,1.8728793126258834,1.1356182999373312,3.4433864453496845,1.038761445699194,2.911763976530236,1.289267000376432,1.965878763574573
2,719
Oxidative phosphorylation
17
55
2.744923
0.006053
P24539,O75964,O14949,P14406,P34897,Q9UDW1,O43676,P56385,P00403,Q7KZN9,Q9BRT2,O75306,Q9H3K2,P03886,Q9BSK2,P13073,P47985
Processes and pathways
GO Biological process
msigdb_gobp
98,34,72,73,363,14,15,336,305,364,406,244,247,26,221,286,408
856,72,15,872,244,513,1924,804,34,858,1289,1598,426,305,26,1072,751,1006,1484,1291,286,73,1930,2317,1602,2225,504,638,98,2476,2693,1485,1714,807,363,794,983,408,2520,2559,769,2228,852,336,1740,1057,1307,2136,364,2470,406,221,247,14,1087
0.1905477242530135,2.4828960163826035,3.4199522827989974,0.17611273471205496,1.3586851022140123,0.6188981125431084,-0.5036894974780469,0.2478813025768698,2.971565848245718,0.1905477242530135,-0.13692690238543065,-0.3089938532666943,0.78839669765801,1.147599572470142,3.105839691433299,0.014556932935040613,0.30457623372576403,0.07390195373379957,-0.23005094416154934,-0.13692690238543065,1.2189142308211247,2.4828960163826035,-0.5036894974780469,-0.7756984250375901,-0.3089938532666943,-0.6890863348428883,0.632136528586786,0.44361639063605623,2.215993204297903,-0.9536034576855446,-2.0224789299810415,-0.23005094416154934,-0.37305474027032975,0.2478813025768698,0.9525040135933169,0.26211431465637414,0.08863020155351369,0.826732699034428,-1.0265997707300218,-1.1006945383567346,0.29046154644551864,-0.6890863348428883,0.20494183108481331,1.0265264066984594,-0.38919874485326694,0.029458532651360454,-0.13692690238543065,-0.620867881511793,0.9525040135933169,-0.9355219790549657,0.8394483821163174,1.4498335257671533,1.3586851022140123,3.427774762153474,0.014556932935040613
2,719
Slc mediated transmembrane transport
9
16
2.741168
0.006122
Q15043,Q9UBX3,P05141,P35613,Q70HW3,Q8TB61,P12236,Q96QD8,P12235
Processes and pathways
Reactome Pathways
msigdb_reactome
386,38,327,263,76,78,143,147,186
327,806,186,143,1604,263,1772,823,471,386,864,2337,76,78,147,38
1.0631453851685053,0.2478813025768698,1.605631086088607,1.8832934520415403,-0.3089938532666943,1.2776071666564428,-0.4053949717396913,0.23360837776605786,0.6978221404482146,0.8774087768247075,0.1905477242530135,-0.7932038385838693,2.436197942025277,2.379619278698563,1.8728793126258834,2.911763976530236
2,719
Bulbar signs
7
11
2.735095
0.006236
Q15043,Q99720,P04062,P07602,Q9NZJ7,P35637,P03886
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
386,36,71,168,265,276,26
389,26,71,1734,168,276,1074,386,969,36,265
0.8647862588625002,3.105839691433299,2.5107215183813394,-0.38919874485326694,1.69263057727874,1.2424706616319041,0.014556932935040613,0.8774087768247075,0.10331578012873843,2.946016924906694,1.2776071666564428
2,719
Sphingolipid pathway
6
9
2.733978
0.006257
Q06136,Q13510,P04062,Q96G23,Q16739,O95470
Processes and pathways
WikiPathways
msigdb_wp
65,35,71,45,83,93
260,1070,93,71,2387,65,35,83,45
1.289267000376432,0.014556932935040613,2.245234151230295,2.5107215183813394,-0.8460943992105768,2.5750940135788953,2.971565848245718,2.3511047492659554,2.798926517414969
2,719
Electron transport chain oxphos system in mitochondria
17
46
2.730552
0.006323
P24539,O75964,P05141,P12235,O14949,P14406,Q9UDW1,P12236,O43676,O96000,P00403,P56385,Q7KZN9,O75306,P03886,P13073,P47985
Processes and pathways
WikiPathways
msigdb_wp
98,34,327,186,72,73,14,143,15,426,305,336,364,244,26,286,408
856,72,15,872,244,1924,651,804,34,858,1289,1598,426,305,26,327,751,1796,1291,186,143,286,73,2317,1602,2225,504,444,638,98,2476,2693,1714,807,794,408,2520,2559,769,852,336,1057,1307,364,14,998
0.1905477242530135,2.4828960163826035,3.4199522827989974,0.17611273471205496,1.3586851022140123,-0.5036894974780469,0.4298814338746595,0.2478813025768698,2.971565848245718,0.1905477242530135,-0.13692690238543065,-0.3089938532666943,0.78839669765801,1.147599572470142,3.105839691433299,1.0631453851685053,0.30457623372576403,-0.421643782078971,-0.13692690238543065,1.605631086088607,1.8832934520415403,1.2189142308211247,2.4828960163826035,-0.7756984250375901,-0.3089938532666943,-0.6890863348428883,0.632136528586786,0.7497737515679389,0.44361639063605623,2.215993204297903,-0.9536034576855446,-2.0224789299810415,-0.37305474027032975,0.2478813025768698,0.26211431465637414,0.826732699034428,-1.0265997707300218,-1.1006945383567346,0.29046154644551864,0.20494183108481331,1.0265264066984594,0.029458532651360454,-0.13692690238543065,0.9525040135933169,3.427774762153474,0.08863020155351369
2,719
Liposaccharide metabolic process
6
16
2.73046
0.006325
P06280,P17900,P04062,P16278,P06865,Q16739
Processes and pathways
GO Biological process
msigdb_gobp
226,135,71,206,177,83
248,682,71,1034,226,177,1818,206,135,1391,83,429,688,1698,1281,679
1.3471792062317862,0.38845375763582707,2.5107215183813394,0.04431638803769443,1.4271945957883734,1.6275159466122078,-0.43794554085718024,1.5060072044287904,1.9247467241533158,-0.18327357472878134,2.3511047492659554,0.78839669765801,0.38845375763582707,-0.3569626006240997,-0.12157226993528147,0.402300331182603
2,719
Amino acid transport
9
15
2.719331
0.006541
O60831,O75915,Q9UJS0,O75746,Q96H78,Q9H9B4,Q6P4A7,Q96QD8,Q9Y619
Processes and pathways
GO Biological process
msigdb_gobp
95,383,262,449,70,334,210,147,125
2040,95,449,383,1650,806,471,864,210,70,646,147,334,262,125
-0.5703108638932032,2.22575796347679,0.736834876495512,0.8774087768247075,-0.3409219722772057,0.2478813025768698,0.6978221404482146,0.1905477242530135,1.494820444712504,2.5199648159717087,0.44361639063605623,1.8728793126258834,1.038761445699194,1.289267000376432,1.965878763574573
2,719
Nadh dehydrogenase complex assembly
6
21
2.708758
0.006754
Q96CU9,Q15070,Q9P0J0,O43676,P03886,Q9H061
Processes and pathways
GO Biological process
msigdb_gobp
39,141,204,15,26,27
15,872,244,1924,858,1598,426,26,2693,769,141,1057,1307,39,890,27,1956,608,1175,204,1235
3.4199522827989974,0.17611273471205496,1.3586851022140123,-0.5036894974780469,0.1905477242530135,-0.3089938532666943,0.78839669765801,3.105839691433299,-2.0224789299810415,0.29046154644551864,1.9040605759318283,0.029458532651360454,-0.13692690238543065,2.894556239112553,0.17611273471205496,3.0892351012046553,-0.5036894974780469,0.49819048944279026,-0.04549245437206825,1.5394252878937733,-0.09100256702323781
2,719
Mitochondrial nucleotide transporter subfamily
6
8
2.700442
0.006925
Q70HW3,Q9H2D1,Q6NUK1,P12236,P12235,Q9BSK2
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
76,13,299,143,186,221
600,327,186,143,299,76,221,13
0.49819048944279026,1.0631453851685053,1.605631086088607,1.8832934520415403,1.1595533384376537,2.436197942025277,1.4498335257671533,3.4433864453496845
2,719
Molecular carrier activity
18
33
2.69112
0.007121
Q9Y5L0,Q8TEX9,O00505,O43819,O60684,Q15070,P62072,Q9NPA0,Q14974,Q9HAV4,Q5J8M3,O00410,Q9BV81,O60518,Q92973,P10909,P52294,P40855
Functions
GO Molecular function
msigdb_gomf
546,133,325,511,455,141,10,463,349,499,337,402,541,438,90,466,220,317
402,325,2474,1793,1481,511,438,455,651,466,1240,1504,317,1606,220,835,10,1188,349,839,141,337,1862,133,90,1280,2470,541,585,499,463,1031,546
0.8394483821163174,1.0631453851685053,-0.9536034576855446,-0.421643782078971,-0.23005094416154934,0.6188981125431084,0.7626802321711698,0.723863433268658,0.4298814338746595,0.6978221404482146,-0.10626425831084813,-0.24574059272730153,1.111572693459288,-0.3089938532666943,1.4498335257671533,0.2192953010576298,3.4899576845407503,-0.0606169582349026,0.9896472724402028,0.2192953010576298,1.9040605759318283,1.0265264066984594,-0.4543006169521521,1.9350596419712964,2.2646396892872667,-0.12157226993528147,-0.9355219790549657,0.5923184989479339,0.5252609862464442,0.6453409341751739,0.7108592467728196,0.05913077172037472,0.5789769223558233
2,719