term
stringlengths
2
121
overlap
int64
6
281
setsize
int64
7
499
score
float64
1.96
10.6
pval
float64
0
0.05
edge
stringlengths
41
1.97k
type
stringclasses
5 values
subtype
stringclasses
24 values
subtype_key
stringclasses
24 values
edge_idxs
stringlengths
11
1.17k
ann_idxs
stringlengths
19
2.31k
ann_vals
stringlengths
124
9.94k
sig_size
int64
2.2k
3.73k
Sphingolipid metabolism in senescence
6
10
2.679556
0.007372
Q06136,Q13510,P04062,Q96G23,P16278,Q16739
Processes and pathways
WikiPathways
msigdb_wp
65,35,71,45,206,83
260,71,683,206,1770,913,65,35,83,45
1.289267000376432,2.5107215183813394,0.38845375763582707,1.5060072044287904,-0.4053949717396913,0.1471191126541989,2.5750940135788953,2.971565848245718,2.3511047492659554,2.798926517414969
2,719
Organic acid transport
16
38
2.673752
0.007501
O60831,O75915,P08183,Q9UJS0,P09455,Q9UBX3,O75746,Q96H78,Q9H2D1,Q9H9B4,Q6P4A7,Q96QD8,Q9BQT8,P55011,O43772,Q9Y619
Processes and pathways
GO Biological process
msigdb_gobp
95,383,322,262,422,38,449,70,13,334,210,147,311,471,437,125
2040,437,600,95,449,383,1182,1894,2122,1650,2273,322,806,422,1355,478,740,1111,1385,629,781,823,471,2132,677,864,2337,210,70,646,147,311,13,334,38,262,830,125
-0.5703108638932032,0.7626802321711698,0.49819048944279026,2.22575796347679,0.736834876495512,0.8774087768247075,-0.0606169582349026,-0.48717221640031005,-0.620867881511793,-0.3409219722772057,-0.7235499894095512,1.087415425314427,0.2478813025768698,0.8012070229052979,-0.1677772467277911,0.6847519362737263,0.3186519434677123,-0.015378603154741318,-0.18327357472878134,0.457314566306333,0.2763076509973368,0.23360837776605786,0.6978221404482146,-0.620867881511793,0.402300331182603,0.1905477242530135,-0.7932038385838693,1.494820444712504,2.5199648159717087,0.44361639063605623,1.8728793126258834,1.1356182999373312,3.4433864453496845,1.038761445699194,2.911763976530236,1.289267000376432,0.23360837776605786,1.965878763574573
2,719
Peptide binding
26
65
2.667069
0.007652
Q8TEX9,O14773,P24390,O00410,Q99735,Q15392,Q9BYT8,P10321,O60518,P40855,Q03518,O00505,O60684,O00264,Q9NQX7,Q9UHV9,Q92973,Q15388,P52294,Q14974,P10909,P09497,Q8WTV0,Q9UIQ6,P42892,Q9NZ08
Functions
GO Molecular function
msigdb_gomf
133,134,9,402,420,52,180,312,438,317,447,325,455,335,214,344,90,219,220,349,466,353,110,115,239,254
335,402,325,134,2474,1069,2068,1678,438,455,628,1457,1239,955,353,312,466,1931,2612,2299,9,2367,1485,982,1504,1574,317,239,2153,2078,1937,1606,220,1200,491,2156,1715,550,1553,447,1466,1040,1467,1906,349,2658,219,52,133,110,90,949,1397,420,2623,180,2200,719,214,254,648,344,115,2607,1066
1.0265264066984594,0.8394483821163174,1.0631453851685053,1.9247467241533158,-0.9536034576855446,0.014556932935040613,-0.587106244130671,-0.3569626006240997,0.7626802321711698,0.723863433268658,0.457314566306333,-0.2144101059765268,-0.10626425831084813,0.10331578012873843,0.9772957319876318,1.123609385664931,0.6978221404482146,-0.5036894974780469,-1.233112298811929,-0.7582546181179882,3.672408462929854,-0.8284013522129561,-0.23005094416154934,0.08863020155351369,-0.24574059272730153,-0.2931056735100328,1.111572693459288,1.3701657615426401,-0.6378349653375106,-0.587106244130671,-0.5036894974780469,-0.3089938532666943,1.4498335257671533,-0.07578689853775272,0.6585115148857332,-0.6378349653375106,-0.37305474027032975,0.5656005771908399,-0.2772676267666931,0.7497737515679389,-0.2144101059765268,0.04431638803769443,-0.2144101059765268,-0.48717221640031005,0.9896472724402028,-1.4688005294598216,1.4611164567099202,2.74604529197796,1.9350596419712964,2.1471356130946906,2.2646396892872667,0.11795895191442474,-0.18327357472878134,0.8139856344410125,-1.2716124786728344,1.6275159466122078,-0.6548601180580003,0.34668734253092304,1.483609806203434,1.3125089094881686,0.44361639063605623,1.014262462244214,2.097402027546233,-1.213975141317416,0.029458532651360454
2,719
Cherry red spot of the macula
6
9
2.665936
0.007677
Q13510,P17900,P07602,P16278,P06865,P10619
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
35,135,168,206,177,89
177,168,1818,89,1821,206,135,35,265
1.6275159466122078,1.69263057727874,-0.43794554085718024,2.2936167157241867,-0.43794554085718024,1.5060072044287904,1.9247467241533158,2.971565848245718,1.2776071666564428
2,719
Azurophil granule membrane
8
16
2.664501
0.00771
P07602,Q9NZJ7,O15260,Q07065,P42785,Q9NQX7,Q8NF37,P10253
Localization
GO Cellular component
msigdb_gocc
168,265,330,211,117,214,373,380
330,2247,168,380,1292,1199,117,1361,211,915,373,453,1752,214,265,1404
1.0509677239800752,-0.7062882632563935,1.69263057727874,0.8900005618991303,-0.13692690238543065,-0.07578689853775272,2.07737796601851,-0.1677772467277911,1.483609806203434,0.1471191126541989,0.9150925679330987,0.736834876495512,-0.38919874485326694,1.483609806203434,1.2776071666564428,-0.18327357472878134
2,719
Cytochrome complex assembly
8
12
2.661095
0.007789
Q69YU5,P53701,Q15070,Q7KZN9,Q9BRT2,Q6DKK2,Q9BSK2,P47985
Processes and pathways
GO Biological process
msigdb_gobp
131,199,141,364,406,118,221,408
511,651,408,199,141,131,118,364,406,1151,221,1235
0.6188981125431084,0.4298814338746595,0.826732699034428,1.5615865779228295,1.9040605759318283,1.9350596419712964,2.04720003960902,0.9525040135933169,0.8394483821163174,-0.030413098045804464,1.4498335257671533,-0.09100256702323781
2,719
Cellular monovalent inorganic cation homeostasis
10
20
2.659028
0.007837
P51790,P05023,Q9Y487,O75503,Q15904,Q8N511,Q93050,Q96PU5,P50897,P61421
Processes and pathways
GO Biological process
msigdb_gobp
261,295,395,231,240,48,401,474,24,348
231,295,751,1653,1770,24,1297,261,1114,471,348,240,48,401,644,474,1178,973,395,2608
1.404457491582026,1.1714797320050525,0.30457623372576403,-0.3409219722772057,-0.4053949717396913,3.1471316821409943,-0.13692690238543065,1.289267000376432,-0.015378603154741318,0.6978221404482146,0.9896472724402028,1.3701657615426401,2.763729779838205,0.8521328477933847,0.44361639063605623,0.6978221404482146,-0.04549245437206825,0.10331578012873843,0.8647862588625002,-1.213975141317416
2,719
Tetrapyrrole binding
10
17
2.655728
0.007914
P53701,P09601,O15173,Q9Y5Z4,Q7KZN9,O00264,Q8WUJ1,O43169,Q16850,P30519
Functions
GO Molecular function
msigdb_gomf
199,40,107,236,364,335,241,50,154,30
335,107,50,1006,40,2366,30,199,154,364,241,435,1751,719,2671,766,236
1.0265264066984594,2.1767547750820517,2.7548947540582653,0.07390195373379957,2.859976400730297,-0.8284013522129561,3.0475012788562985,1.5615865779228295,1.7888209300317397,0.9525040135933169,1.3701657615426401,0.7755544905767453,-0.38919874485326694,0.34668734253092304,-1.5704713475646683,0.30457623372576403,1.3930518398628324
2,719
Organelle membrane contact site
11
18
2.651632
0.00801
Q96N66,Q96JX3,Q9Y320,P51572,Q96TC7,O95772,P27824,Q9NTJ5,Q14849,Q15388,Q5XKP0
Localization
GO Cellular component
msigdb_gocc
127,289,483,385,488,233,522,574,87,219,155
908,979,980,233,609,522,385,87,219,155,826,289,127,709,488,1954,574,483
0.1471191126541989,0.08863020155351369,0.08863020155351369,1.3930518398628324,0.4846014092491796,0.6056254989038173,0.8774087768247075,2.3128479941750375,1.4611164567099202,1.7782191520986066,0.23360837776605786,1.195250933615223,1.945352566311608,0.3606474828614861,0.671648454750572,-0.5036894974780469,0.5387428051993683,0.6847519362737263
2,719
Alcohol binding
8
14
2.650045
0.008048
Q14108,P09455,O95772,P21796,O15118,Q9BZF1,P45880,Q14849
Functions
GO Molecular function
msigdb_gomf
193,422,233,12,273,281,22,87
273,682,1762,233,2103,422,12,1137,22,446,193,87,2334,281
1.2542091223510612,0.38845375763582707,-0.4053949717396913,1.3930518398628324,-0.6039584463179856,0.8012070229052979,3.451175716066335,-0.030413098045804464,3.253054371219224,0.7497737515679389,1.5836549017230799,2.3128479941750375,-0.7932038385838693,1.2424706616319041
2,719
Outer mitochondrial membrane protein complex
10
15
2.636701
0.008372
Q8N4H5,Q13505,Q9NS69,Q9NX63,O96008,Q9Y512,Q9BUR5,Q16891,Q15388,Q5XKP0
Localization
GO Cellular component
msigdb_gocc
104,105,11,367,609,502,179,404,219,155
1090,628,609,2279,105,219,404,155,1061,104,179,11,721,367,502
-0.00038868636313022414,0.457314566306333,0.4846014092491796,-0.7235499894095512,2.1865914316960353,1.4611164567099202,0.8394483821163174,1.7782191520986066,0.029458532651360454,2.1964100084149285,1.6275159466122078,3.474477642713755,0.34668734253092304,0.9525040135933169,0.6453409341751739
2,719
Endoplasmic reticulum organization
18
39
2.631747
0.008495
Q15629,Q12907,Q15363,Q12981,P57088,P61026,O43681,O95197,Q9NPA0,Q9H6H4,Q00765,Q9NQC3,Q5J8M3,O15027,Q9P2W9,Q96A33,P49257,P46379
Processes and pathways
GO Biological process
msigdb_gobp
96,418,69,228,297,492,389,43,463,333,460,109,337,237,20,213,470,191
908,2296,1180,1677,237,1481,389,1002,2248,43,981,191,470,297,492,1715,460,418,228,839,69,96,337,2482,885,2699,1862,1276,213,2063,541,1122,333,1174,463,109,1014,1404,20
0.1471191126541989,-0.7582546181179882,-0.0606169582349026,-0.3569626006240997,1.3816213018328303,-0.23005094416154934,0.8647862588625002,0.07390195373379957,-0.7062882632563935,2.798926517414969,0.08863020155351369,1.594654460100512,0.6978221404482146,1.1714797320050525,0.6585115148857332,-0.37305474027032975,0.7108592467728196,0.8139856344410125,1.4271945957883734,0.2192953010576298,2.5199648159717087,2.22575796347679,1.0265264066984594,-0.9536034576855446,0.17611273471205496,-2.2773891393535837,-0.4543006169521521,-0.12157226993528147,1.483609806203434,-0.5703108638932032,0.5923184989479339,-0.015378603154741318,1.038761445699194,-0.04549245437206825,0.7108592467728196,2.157026937488641,0.07390195373379957,-0.18327357472878134,3.317234140715181
2,719
Nucleobase containing compound transmembrane transporter activity
7
11
2.626031
0.008639
P05141,Q9H2D1,Q8TB61,P12236,Q6NUK1,P12235,Q9BSK2
Functions
GO Molecular function
msigdb_gomf
327,13,78,143,299,186,221
375,600,327,186,143,1385,810,299,78,221,13
0.9025617730365805,0.49819048944279026,1.0631453851685053,1.605631086088607,1.8832934520415403,-0.18327357472878134,0.2478813025768698,1.1595533384376537,2.379619278698563,1.4498335257671533,3.4433864453496845
2,719
Respirasome
14
39
2.622105
0.008739
Q96CU9,O14949,P14406,Q9P0J0,Q9UDW1,O43676,O96000,P00403,Q7KZN9,O75306,Q6DKK2,P03886,P13073,P47985
Localization
GO Cellular component
msigdb_gocc
39,72,73,204,14,15,426,305,364,244,118,26,286,408
856,72,15,872,244,1924,858,1289,1598,426,305,26,1006,1796,1291,286,73,2317,1602,2225,504,444,638,2693,1714,807,408,2559,769,1304,1057,1307,118,364,39,608,204,14,1235
0.1905477242530135,2.4828960163826035,3.4199522827989974,0.17611273471205496,1.3586851022140123,-0.5036894974780469,0.1905477242530135,-0.13692690238543065,-0.3089938532666943,0.78839669765801,1.147599572470142,3.105839691433299,0.07390195373379957,-0.421643782078971,-0.13692690238543065,1.2189142308211247,2.4828960163826035,-0.7756984250375901,-0.3089938532666943,-0.6890863348428883,0.632136528586786,0.7497737515679389,0.44361639063605623,-2.0224789299810415,-0.37305474027032975,0.2478813025768698,0.826732699034428,-1.1006945383567346,0.29046154644551864,-0.13692690238543065,0.029458532651360454,-0.13692690238543065,2.04720003960902,0.9525040135933169,2.894556239112553,0.49819048944279026,1.5394252878937733,3.427774762153474,-0.09100256702323781
2,719
Nucleotide transport
7
10
2.617064
0.008869
Q9H2D1,Q6NUK1,Q8TB61,P12236,P12235,Q08722,Q9BSK2
Processes and pathways
GO Biological process
msigdb_gobp
13,299,78,143,186,188,221
600,327,186,143,1385,188,299,78,221,13
0.49819048944279026,1.0631453851685053,1.605631086088607,1.8832934520415403,-0.18327357472878134,1.605631086088607,1.1595533384376537,2.379619278698563,1.4498335257671533,3.4433864453496845
2,719
Organophosphate ester transmembrane transporter activity
6
9
2.615199
0.008918
Q9H2D1,Q6NUK1,Q8TB61,P12236,P12235,Q9BSK2
Functions
GO Molecular function
msigdb_gomf
13,299,78,143,186,221
600,327,186,143,1385,299,78,221,13
0.49819048944279026,1.0631453851685053,1.605631086088607,1.8832934520415403,-0.18327357472878134,1.1595533384376537,2.379619278698563,1.4498335257671533,3.4433864453496845
2,719
Nucleotide transmembrane transporter activity
6
9
2.615199
0.008918
Q9H2D1,Q6NUK1,Q8TB61,P12236,P12235,Q9BSK2
Functions
GO Molecular function
msigdb_gomf
13,299,78,143,186,221
600,327,186,143,1385,299,78,221,13
0.49819048944279026,1.0631453851685053,1.605631086088607,1.8832934520415403,-0.18327357472878134,1.1595533384376537,2.379619278698563,1.4498335257671533,3.4433864453496845
2,719
Oxidative phosphorylation
19
54
2.614706
0.00893
Q9Y487,Q9UDW1,O43676,Q93050,P03886,P13073,P47985,O75964,O96000,P00403,O14949,P14406,P56385,Q9Y5K8,P61421,P24539,Q7KZN9,Q15904,O75306
Processes and pathways
KEGG Pathways
msigdb_kegg
395,14,15,401,26,286,408,34,426,305,72,73,336,341,348,98,364,240,244
856,72,15,872,244,1924,804,34,858,1289,1598,426,305,26,751,1006,1796,1291,286,73,2317,1602,2225,504,877,2404,444,638,98,2476,2693,1714,807,794,515,2182,408,2520,2559,769,852,336,348,2602,240,1057,1307,364,401,2572,14,973,395,341
0.1905477242530135,2.4828960163826035,3.4199522827989974,0.17611273471205496,1.3586851022140123,-0.5036894974780469,0.2478813025768698,2.971565848245718,0.1905477242530135,-0.13692690238543065,-0.3089938532666943,0.78839669765801,1.147599572470142,3.105839691433299,0.30457623372576403,0.07390195373379957,-0.421643782078971,-0.13692690238543065,1.2189142308211247,2.4828960163826035,-0.7756984250375901,-0.3089938532666943,-0.6890863348428883,0.632136528586786,0.17611273471205496,-0.8638509468356808,0.7497737515679389,0.44361639063605623,2.215993204297903,-0.9536034576855446,-2.0224789299810415,-0.37305474027032975,0.2478813025768698,0.26211431465637414,0.6188981125431084,-0.6548601180580003,0.826732699034428,-1.0265997707300218,-1.1006945383567346,0.29046154644551864,0.20494183108481331,1.0265264066984594,0.9896472724402028,-1.213975141317416,1.3701657615426401,0.029458532651360454,-0.13692690238543065,0.9525040135933169,0.8521328477933847,-1.119394022350341,3.427774762153474,0.10331578012873843,0.8647862588625002,1.0265264066984594
2,719
Abnormal biliary tract morphology
12
21
2.605025
0.009187
Q14108,Q9Y5L0,P04062,P09601,Q9NZJ7,P07602,O43681,Q96J02,Q14739,Q13043,Q10713,Q5XKP0
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
193,546,71,40,265,168,389,301,207,372,540,155
389,1354,71,168,40,1355,2612,1268,851,540,372,193,207,155,2061,301,1701,265,597,1235,546
0.8647862588625002,-0.1677772467277911,2.5107215183813394,1.69263057727874,2.859976400730297,-0.1677772467277911,-1.233112298811929,-0.12157226993528147,0.20494183108481331,0.5923184989479339,0.9275931030431922,1.5836549017230799,1.5060072044287904,1.7782191520986066,-0.5703108638932032,1.1595533384376537,-0.3569626006240997,1.2776071666564428,0.5117436144293259,-0.09100256702323781,0.5789769223558233
2,719
Overlap between signal transduction pathways contributing to lmna laminopathies
6
12
2.602584
0.009252
P48729,P42166,O60725,P55209,O75844,P42167
Processes and pathways
WikiPathways
msigdb_wp
227,390,77,144,82,346
77,82,1354,683,1198,390,346,227,403,144,1368,737
2.379619278698563,2.3511047492659554,-0.1677772467277911,0.38845375763582707,-0.07578689853775272,0.8647862588625002,1.0019694664850602,1.4271945957883734,0.8394483821163174,1.8832934520415403,-0.1677772467277911,0.332688904231155
2,719
Endoplasmic reticulum golgi intermediate compartment
17
44
2.589991
0.009598
Q10472,Q9Y282,Q12907,P80303,P51572,Q969X5,Q15363,P24390,Q9Y3B3,O15260,Q9H0U4,Q02818,Q15904,Q8N511,O15258,P49257,Q03518
Localization
GO Cellular component
msigdb_gocc
224,2,418,4,385,392,69,9,202,330,366,140,240,48,371,470,447
371,330,1622,1004,728,896,9,2367,982,470,495,1938,385,2386,1244,1420,4,140,447,224,418,592,2614,69,240,966,841,48,1279,2009,392,2633,932,2528,366,1591,2036,1178,2377,2,562,202,1157,1158
0.9275931030431922,1.0509677239800752,-0.32493250526949763,0.07390195373379957,0.332688904231155,0.16163661432793977,3.672408462929854,-0.8284013522129561,0.08863020155351369,0.6978221404482146,0.6453409341751739,-0.5036894974780469,0.8774087768247075,-0.8460943992105768,-0.10626425831084813,-0.19881775585569805,3.8779358569118827,1.9040605759318283,0.7497737515679389,1.4385262761005175,0.8139856344410125,0.5117436144293259,-1.233112298811929,2.5199648159717087,1.3701657615426401,0.10331578012873843,0.2192953010576298,2.763729779838205,-0.12157226993528147,-0.5368889474821656,0.8647862588625002,-1.31041805381167,0.13255997690276794,-1.0265997707300218,0.9525040135933169,-0.2931056735100328,-0.5535718990503548,-0.04549245437206825,-0.8284013522129561,4.013195205240466,0.552189269880853,1.5505176058047423,-0.030413098045804464,-0.030413098045804464
2,719
secondary carrier transporter
9
12
2.589763
0.009604
Q15043,Q9UJS0,O75746,O95202,Q96H78,Q9UBX3,Q96ES6,Q8TB61,Q9BQT8
Functions
Panther Protein class
panther_protein_class
386,262,449,326,70,38,300,78,311
449,326,471,677,386,2337,78,300,70,311,38,262
0.736834876495512,1.0631453851685053,0.6978221404482146,0.402300331182603,0.8774087768247075,-0.7932038385838693,2.379619278698563,1.1595533384376537,2.5199648159717087,1.1356182999373312,2.911763976530236,1.289267000376432
2,719
Cholesterol binding
6
11
2.577188
0.009961
Q14108,O95772,P21796,O15118,P45880,Q14849
Functions
GO Molecular function
msigdb_gomf
193,233,12,273,22,87
273,1762,233,2103,12,1137,22,446,193,87,281
1.2542091223510612,-0.4053949717396913,1.3930518398628324,-0.6039584463179856,3.451175716066335,-0.030413098045804464,3.253054371219224,0.7497737515679389,1.5836549017230799,2.3128479941750375,1.2424706616319041
2,719
Phospholipid metabolism
10
13
2.574631
0.010035
Q96N66,Q96JX3,Q9NPH0,Q9UG56,Q99943,P48651,Q8NF37,P35790,O95674,Q9NUQ2
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
127,289,234,235,666,277,373,60,601,519
601,60,277,885,373,690,289,127,666,234,1700,519,235
0.49819048944279026,2.6024486449078035,1.2424706616319041,0.17611273471205496,0.9150925679330987,0.38845375763582707,1.195250933615223,1.945352566311608,0.41610948501277006,1.3930518398628324,-0.3569626006240997,0.6188981125431084,1.3930518398628324
2,719
Dicarboxylic acid transport
7
12
2.572745
0.01009
O60831,O75915,Q9UJS0,O75746,Q9UBX3,Q9H2D1,Q9BQT8
Processes and pathways
GO Biological process
msigdb_gobp
95,383,262,449,38,13,311
95,449,383,1650,1385,471,677,864,311,13,38,262
2.22575796347679,0.736834876495512,0.8774087768247075,-0.3409219722772057,-0.18327357472878134,0.6978221404482146,0.402300331182603,0.1905477242530135,1.1356182999373312,3.4433864453496845,2.911763976530236,1.289267000376432
2,719
Amyloid precursor protein catabolic process
8
16
2.565981
0.010288
Q92542,O95197,Q9NQC3,O75298,P49840,Q15392,P62942,P10909
Processes and pathways
GO Biological process
msigdb_gobp
453,43,109,303,432,52,187,466
832,303,43,466,2075,495,432,187,1906,1526,1203,52,453,1280,1562,109
0.2192953010576298,1.147599572470142,2.798926517414969,0.6978221404482146,-0.587106244130671,0.6453409341751739,0.7755544905767453,1.605631086088607,-0.48717221640031005,-0.2614793772811411,-0.07578689853775272,2.74604529197796,0.736834876495512,-0.12157226993528147,-0.2772676267666931,2.157026937488641
2,719
Disproportionate short stature
10
19
2.558274
0.010519
Q96HY6,O75718,Q32P28,Q6DKJ4,P16278,Q14739,Q15392,O00116,Q9UHX1,P10644
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
356,294,360,123,206,207,52,218,130,31
218,2557,294,31,206,2299,913,1631,1880,207,2435,52,360,123,496,382,356,1672,130
1.4611164567099202,-1.1006945383567346,1.1714797320050525,3.0391160654016716,1.5060072044287904,-0.7582546181179882,0.1471191126541989,-0.32493250526949763,-0.47070938318962924,1.5060072044287904,-0.8995564994467704,2.74604529197796,0.9649146958521644,1.965878763574573,0.6453409341751739,0.8900005618991303,0.9772957319876318,-0.3409219722772057,1.945352566311608
2,719
Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen
9
23
2.547278
0.010857
P09601,Q32P28,O75845,P16435,Q8NB78,Q9BU89,Q15800,Q16850,P30519
Functions
GO Molecular function
msigdb_gomf
40,360,203,238,112,374,23,154,30
1032,2121,2400,203,490,728,40,384,238,30,861,1943,1273,23,154,360,2649,1395,1335,112,374,2239,854
0.04431638803769443,-0.620867881511793,-0.8638509468356808,1.5394252878937733,0.6585115148857332,0.332688904231155,2.859976400730297,0.8774087768247075,1.3816213018328303,3.0475012788562985,0.1905477242530135,-0.5036894974780469,-0.12157226993528147,3.2287919262177374,1.7888209300317397,0.9649146958521644,-1.428719909350296,-0.18327357472878134,-0.15232845914399104,2.1272977913157143,0.9150925679330987,-0.6890863348428883,0.20494183108481331
2,719
Abnormal tissue metabolite concentration
7
11
2.546916
0.010868
P06280,P17900,P07602,Q9NZJ7,O43681,P06865,P40855
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
226,135,168,265,389,177,317
389,417,226,177,168,1818,135,317,851,265,1235
0.8647862588625002,0.8139856344410125,1.4271945957883734,1.6275159466122078,1.69263057727874,-0.43794554085718024,1.9247467241533158,1.111572693459288,0.20494183108481331,1.2776071666564428,-0.09100256702323781
2,719
Intracellular protein transmembrane transport
9
20
2.542597
0.011003
Q15629,O75381,Q99595,O75298,Q9UGP8,O60830,O14925,Q15388,O43615
Processes and pathways
GO Biological process
msigdb_gobp
96,417,6,303,79,19,54,219,379
54,379,19,303,417,628,465,609,2430,1462,2156,1715,219,96,714,2114,1282,6,1401,79
2.6657421041309006,0.8900005618991303,3.317234140715181,1.147599572470142,0.8139856344410125,0.457314566306333,0.6978221404482146,0.4846014092491796,-0.8995564994467704,-0.2144101059765268,-0.6378349653375106,-0.37305474027032975,1.4611164567099202,2.22575796347679,0.34668734253092304,-0.6039584463179856,-0.12157226993528147,3.7466882849921066,-0.18327357472878134,2.379619278698563
2,719
Outer membrane
30
81
2.537815
0.011155
Q9Y371,Q9Y6C9,O75323,Q9NZJ7,Q9NS69,P21796,Q9Y277,P52789,Q16891,P45880,P50402,Q5XKP0,Q99720,Q8N0X7,P09601,Q8WY22,O43169,Q9BUR5,P57105,O00264,O60313,Q15388,Q8N4H5,Q13505,Q96TC7,Q9NX63,Q9Y512,Q9BWH2,Q07820,Q9NUQ2
Localization
GO Cellular component
msigdb_gocc
520,257,513,265,11,12,146,278,404,22,403,155,36,553,40,46,50,179,445,335,209,219,104,105,488,367,502,246,377,519
335,1180,2707,50,209,980,513,1090,628,941,1182,609,1625,2499,712,40,1019,12,1111,2279,913,1852,22,403,629,278,2303,445,551,1391,377,2331,105,1972,219,2232,1780,404,1393,1530,155,1061,817,865,1494,553,104,1012,866,948,931,46,1496,888,488,699,593,36,2670,179,1256,246,1699,2012,2671,1402,11,519,1347,721,1284,367,1014,265,1672,1126,146,520,830,502,257
1.0265264066984594,-0.0606169582349026,-3.0796995145193136,2.7548947540582653,1.494820444712504,0.08863020155351369,0.6188981125431084,-0.00038868636313022414,0.457314566306333,0.11795895191442474,-0.0606169582349026,0.4846014092491796,-0.32493250526949763,-0.9899664782882975,0.34668734253092304,2.859976400730297,0.05913077172037472,3.451175716066335,-0.015378603154741318,-0.7235499894095512,0.1471191126541989,-0.4543006169521521,3.253054371219224,0.8394483821163174,0.457314566306333,1.2424706616319041,-0.7582546181179882,0.7497737515679389,0.5656005771908399,-0.18327357472878134,0.9025617730365805,-0.7932038385838693,2.1865914316960353,-0.5202616114390414,1.4611164567099202,-0.6890863348428883,-0.4053949717396913,0.8394483821163174,-0.18327357472878134,-0.2614793772811411,1.7782191520986066,0.029458532651360454,0.2478813025768698,0.1905477242530135,-0.23005094416154934,0.5656005771908399,2.1964100084149285,0.07390195373379957,0.1905477242530135,0.11795895191442474,0.13255997690276794,2.7901487387656845,-0.23005094416154934,0.17611273471205496,0.671648454750572,0.37456954772114676,0.5117436144293259,2.946016924906694,-1.5704713475646683,1.6275159466122078,-0.10626425831084813,1.3586851022140123,-0.3569626006240997,-0.5368889474821656,-1.5704713475646683,-0.18327357472878134,3.474477642713755,0.6188981125431084,-0.15232845914399104,0.34668734253092304,-0.12157226993528147,0.9525040135933169,0.07390195373379957,1.2776071666564428,-0.3409219722772057,-0.015378603154741318,1.8832934520415403,0.6188981125431084,0.23360837776605786,0.6453409341751739,1.3125089094881686
2,719
Inner mitochondrial membrane organization
9
19
2.531783
0.011348
O95202,Q13505,P62072,Q9P0J0,Q9NX63,O60313,Q9BUR5,Q9H3K2,Q5XKP0
Processes and pathways
GO Biological process
msigdb_gobp
326,105,10,204,367,209,179,247,155
209,1090,628,326,2279,10,105,404,1393,155,1061,179,247,721,367,204,1316,502,2672
1.494820444712504,-0.00038868636313022414,0.457314566306333,1.0631453851685053,-0.7235499894095512,3.4899576845407503,2.1865914316960353,0.8394483821163174,-0.18327357472878134,1.7782191520986066,0.029458532651360454,1.6275159466122078,1.3586851022140123,0.34668734253092304,0.9525040135933169,1.5394252878937733,-0.13692690238543065,0.6453409341751739,-1.5704713475646683
2,719
Serine hydrolase activity
6
18
2.5297
0.011416
P10619,O14773,Q9HB40,P42785,Q5JRX3,P67812
Functions
GO Molecular function
msigdb_gomf
89,134,113,117,53,152
134,563,514,89,1766,1458,1268,117,960,1200,1244,152,2683,1491,53,1861,259,113
1.9247467241533158,0.5387428051993683,0.6188981125431084,2.2936167157241867,-0.4053949717396913,-0.2144101059765268,-0.12157226993528147,2.07737796601851,0.10331578012873843,-0.07578689853775272,-0.10626425831084813,1.8310169016228028,-1.7590293673389303,-0.23005094416154934,2.701579665755794,-0.4543006169521521,1.3009008737170185,2.1173511478930376
2,719
Cataract
6
22
2.522621
0.011648
Q9H6K4,O76024,Q9H078,Q9UG56,Q15800,O00116
Drugs and Diseases
Protein Atlas Disease involvement
protein_atlas_disease_involvement
225,167,172,235,23,218
218,167,1109,293,1196,2125,1268,1359,1777,1039,23,1393,2569,529,887,1439,1170,172,1122,225,2220,235
1.4611164567099202,1.69263057727874,-0.015378603154741318,1.1833788863385122,-0.07578689853775272,-0.620867881511793,-0.12157226993528147,-0.1677772467277911,-0.4053949717396913,0.04431638803769443,3.2287919262177374,-0.18327357472878134,-1.119394022350341,0.6056254989038173,0.17611273471205496,-0.19881775585569805,-0.04549245437206825,1.6710149037139495,-0.015378603154741318,1.4385262761005175,-0.6719437646434965,1.3930518398628324
2,719
Postural tremor
7
16
2.513573
0.011951
Q14108,Q9H6K4,O14773,O75306,P35637,P03886,Q9NR77
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
193,225,134,244,276,26,253
134,1705,244,941,981,26,610,1007,276,548,409,193,2470,225,253,1049
1.9247467241533158,-0.37305474027032975,1.3586851022140123,0.11795895191442474,0.08863020155351369,3.105839691433299,0.4846014092491796,0.07390195373379957,1.2424706616319041,0.5656005771908399,0.826732699034428,1.5836549017230799,-0.9355219790549657,1.4385262761005175,1.3125089094881686,0.04431638803769443
2,719
Inorganic anion transport
13
19
2.513267
0.011962
Q15043,P08183,P51790,Q9UBX3,O43681,P21796,Q9H0H5,Q9C0H2,Q9Y277,P45880,P55011,Q9UHG3,Q00325
Processes and pathways
GO Biological process
msigdb_gobp
386,322,261,38,389,12,594,49,146,22,471,28,566
2067,389,322,12,22,261,604,471,566,677,386,2542,709,49,594,38,28,146,2608
-0.587106244130671,0.8647862588625002,1.087415425314427,3.451175716066335,3.253054371219224,1.289267000376432,0.49819048944279026,0.6978221404482146,0.5387428051993683,0.402300331182603,0.8774087768247075,-1.0635076502293486,0.3606474828614861,2.763729779838205,0.5117436144293259,2.911763976530236,3.0892351012046553,1.8832934520415403,-1.213975141317416
2,719
Abnormal circulating cholesterol concentration
13
31
2.502998
0.012315
P50402,Q9UJS0,P07602,Q9NZJ7,O75845,Q14739,Q8N511,P57740,Q15904,Q9NVI7,Q15392,Q15800,P61916
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
403,262,168,265,203,207,48,472,240,339,52,23,446
1090,203,1354,2043,168,1020,2597,2636,1459,1360,403,1777,472,446,1039,1328,473,1202,207,52,2643,23,240,48,931,716,339,265,1672,262,974
-0.00038868636313022414,1.5394252878937733,-0.1677772467277911,-0.5703108638932032,1.69263057727874,0.05913077172037472,-1.213975141317416,-1.3299369864356707,-0.2144101059765268,-0.1677772467277911,0.8394483821163174,-0.4053949717396913,0.6978221404482146,0.7497737515679389,0.04431638803769443,-0.15232845914399104,0.6978221404482146,-0.07578689853775272,1.5060072044287904,2.74604529197796,-1.3495342310278062,3.2287919262177374,1.3701657615426401,2.763729779838205,0.13255997690276794,0.34668734253092304,1.0265264066984594,1.2776071666564428,-0.3409219722772057,1.289267000376432,0.10331578012873843
2,719
Hydrolase activity acting on glycosyl bonds
9
26
2.502395
0.012336
Q9BTY2,P06280,P04062,P17900,O75503,P16278,O60476,P06865,Q9NUJ1
Functions
GO Molecular function
msigdb_gomf
194,226,71,135,231,206,80,177,190
635,80,521,231,71,1034,226,177,1818,380,1135,847,206,135,1413,2075,849,752,264,1635,2305,1946,655,194,190,2651
0.44361639063605623,2.370131263440487,0.6056254989038173,1.404457491582026,2.5107215183813394,0.04431638803769443,1.4271945957883734,1.6275159466122078,-0.43794554085718024,0.8900005618991303,-0.030413098045804464,0.20494183108481331,1.5060072044287904,1.9247467241533158,-0.19881775585569805,-0.587106244130671,0.20494183108481331,0.30457623372576403,1.2776071666564428,-0.32493250526949763,-0.7582546181179882,-0.5036894974780469,0.4298814338746595,1.5836549017230799,1.605631086088607,-1.428719909350296
2,719
Abnormal retinal vascular morphology
11
45
2.499594
0.012434
Q13510,P17900,P07602,P38435,P21964,P16278,P06865,O75306,P10619,P03886,Q15555
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
35,135,168,139,171,206,177,244,89,26,157
2175,1868,1017,1108,1708,244,2102,1925,26,1457,177,168,1818,2365,89,1135,1821,206,135,693,444,171,1714,1198,1161,1738,2300,139,2538,2462,2185,2215,677,35,1639,1804,157,1746,1277,1063,1064,709,265,1520,803
-0.6548601180580003,-0.47070938318962924,0.05913077172037472,-0.015378603154741318,-0.37305474027032975,1.3586851022140123,-0.6039584463179856,-0.5036894974780469,3.105839691433299,-0.2144101059765268,1.6275159466122078,1.69263057727874,-0.43794554085718024,-0.8284013522129561,2.2936167157241867,-0.030413098045804464,-0.43794554085718024,1.5060072044287904,1.9247467241533158,0.37456954772114676,0.7497737515679389,1.6710149037139495,-0.37305474027032975,-0.07578689853775272,-0.04549245437206825,-0.38919874485326694,-0.7582546181179882,1.9040605759318283,-1.0635076502293486,-0.9355219790549657,-0.6548601180580003,-0.6719437646434965,0.402300331182603,2.971565848245718,-0.32493250526949763,-0.421643782078971,1.7675960795947097,-0.38919874485326694,-0.12157226993528147,0.029458532651360454,0.029458532651360454,0.3606474828614861,1.2776071666564428,-0.24574059272730153,0.26211431465637414
2,719
Hormone metabolic process
9
25
2.496579
0.01254
Q06520,P05023,P16435,Q9HB40,O75844,P42892,Q14849,Q53GQ0,O95470
Processes and pathways
GO Biological process
msigdb_gobp
5,295,238,113,82,239,87,251,93
910,82,93,295,422,1931,2151,238,239,2576,851,1717,5,87,251,323,773,1439,2235,2604,1588,113,1672,1049,634
0.1471191126541989,2.3511047492659554,2.245234151230295,1.1714797320050525,0.8012070229052979,-0.5036894974780469,-0.6378349653375106,1.3816213018328303,1.3701657615426401,-1.138164966594554,0.20494183108481331,-0.37305474027032975,3.7466882849921066,2.3128479941750375,1.335647955135846,1.087415425314427,0.29046154644551864,-0.19881775585569805,-0.6890863348428883,-1.213975141317416,-0.2931056735100328,2.1173511478930376,-0.3409219722772057,0.04431638803769443,0.457314566306333
2,719
Intrinsic component of plasma membrane
34
61
2.491129
0.012734
Q15043,P51572,Q9UJS0,P51790,P35613,Q8N2K0,O43657,O15118,P27824,Q96QD8,O96005,Q12907,P05023,O60637,P16615,P20020,Q9H1Z9,P10321,P12235,Q00325,Q08722,Q92542,P02786,P05141,Q99797,O00264,P55011,P20645,Q9BTU6,O95864,Q8WTV0,Q9NR28,Q9UIQ6,O15031
Localization
GO Cellular component
msigdb_gocc
386,385,262,261,263,529,17,273,522,147,151,418,295,41,547,170,307,312,186,566,188,453,450,327,201,335,471,467,482,490,110,111,115,376
908,335,376,273,1622,563,17,1678,41,490,151,450,1457,295,327,1650,1036,312,1682,1292,956,186,547,170,467,522,793,263,1549,1385,385,261,823,1114,471,566,677,1466,188,418,1274,386,2390,864,798,529,826,110,453,147,201,679,482,2718,307,111,1756,115,262,1839,2680
0.1471191126541989,1.0265264066984594,0.9025617730365805,1.2542091223510612,-0.32493250526949763,0.5387428051993683,3.3727823469299025,-0.3569626006240997,2.833896232595042,0.6585115148857332,1.8310169016228028,0.736834876495512,-0.2144101059765268,1.1714797320050525,1.0631453851685053,-0.3409219722772057,0.04431638803769443,1.123609385664931,-0.3569626006240997,-0.13692690238543065,0.10331578012873843,1.605631086088607,0.5656005771908399,1.6710149037139495,0.6978221404482146,0.6056254989038173,0.26211431465637414,1.2776071666564428,-0.2772676267666931,-0.18327357472878134,0.8774087768247075,1.289267000376432,0.23360837776605786,-0.015378603154741318,0.6978221404482146,0.5387428051993683,0.402300331182603,-0.2144101059765268,1.605631086088607,0.8139856344410125,-0.12157226993528147,0.8774087768247075,-0.8460943992105768,0.1905477242530135,0.26211431465637414,0.6056254989038173,0.23360837776605786,2.1471356130946906,0.736834876495512,1.8728793126258834,1.5615865779228295,0.402300331182603,0.6847519362737263,-11.68517858014328,1.147599572470142,2.1372259219695624,-0.38919874485326694,2.097402027546233,1.289267000376432,-0.43794554085718024,-1.6953569306213772
2,719
Endoplasmic reticulum to golgi vesicle mediated transport
18
55
2.490473
0.012757
Q96PC5,Q9Y282,Q12907,P51572,Q969X5,Q15363,P24390,Q9Y3B3,Q9NR31,Q9H0U4,Q7Z392,O15027,Q6NUQ1,Q9HCU5,Q9P2W9,Q9HD26,P49257,P49755
Processes and pathways
GO Biological process
msigdb_gobp
128,2,418,385,392,69,9,202,531,366,398,237,145,476,20,308,470,495
976,1263,237,1622,1546,1051,1052,1004,2248,981,1132,1323,9,900,1631,470,495,385,2386,2212,2185,2228,771,418,1611,69,1056,2553,2482,145,398,841,2340,1279,969,392,128,932,366,476,308,531,1404,20,2036,2624,1539,2,1982,562,202,2506,1157,974,1158
0.08863020155351369,-0.12157226993528147,1.3816213018328303,-0.32493250526949763,-0.2772676267666931,0.029458532651360454,0.029458532651360454,0.07390195373379957,-0.7062882632563935,0.08863020155351369,-0.030413098045804464,-0.15232845914399104,3.672408462929854,0.16163661432793977,-0.32493250526949763,0.6978221404482146,0.6453409341751739,0.8774087768247075,-0.8460943992105768,-0.6719437646434965,-0.6548601180580003,-0.6890863348428883,0.29046154644551864,0.8139856344410125,-0.3089938532666943,2.5199648159717087,0.029458532651360454,-1.082065937615682,-0.9536034576855446,1.8832934520415403,0.8521328477933847,0.2192953010576298,-0.7932038385838693,-0.12157226993528147,0.10331578012873843,0.8647862588625002,1.945352566311608,0.13255997690276794,0.9525040135933169,0.6978221404482146,1.147599572470142,0.6056254989038173,-0.18327357472878134,3.317234140715181,-0.5535718990503548,-1.2716124786728344,-0.2614793772811411,4.013195205240466,-0.5202616114390414,0.552189269880853,1.5505176058047423,-0.9899664782882975,-0.030413098045804464,0.10331578012873843,-0.030413098045804464
2,719
Receptor
11
22
2.467829
0.013594
Q14108,O75381,Q9UQB8,A6NIH7,P20645,Q9NWX5,Q8WTV0,Q9BUN8,Q9NR77,Q13432,P57105
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
193,417,163,63,467,8,110,116,253,410,445
63,1793,2544,417,2042,1650,956,467,445,410,193,1436,2649,110,1338,116,499,253,8,1647,1540,163
2.5750940135788953,-0.421643782078971,-1.082065937615682,0.8139856344410125,-0.5703108638932032,-0.3409219722772057,0.10331578012873843,0.6978221404482146,0.7497737515679389,0.826732699034428,1.5836549017230799,-0.19881775585569805,-1.428719909350296,2.1471356130946906,-0.15232845914399104,2.087399401896311,0.6453409341751739,1.3125089094881686,3.679881432866782,-0.32493250526949763,-0.2614793772811411,1.7355981785016048
2,719
Glycoside hydrolase superfamily [IPR017853]
6
15
2.464719
0.013712
Q9BTY2,P06280,P04062,P54802,P16278,P06865
Sequence
InterPro Superfamily
interpro_homologous_superfamily
194,226,71,264,206,177
521,71,1034,226,177,1818,806,380,206,752,264,1635,1946,194,1104
0.6056254989038173,2.5107215183813394,0.04431638803769443,1.4271945957883734,1.6275159466122078,-0.43794554085718024,0.2478813025768698,0.8900005618991303,1.5060072044287904,0.30457623372576403,1.2776071666564428,-0.32493250526949763,-0.5036894974780469,1.5836549017230799,-0.00038868636313022414
2,719
Primary active transmembrane transporter activity
20
44
2.452096
0.014203
P36543,Q9UDW1,O43676,P03886,P13073,P47985,P05023,P20020,O96000,P00403,Q03518,P08183,Q9P0J0,Q9Y5K8,Q15388,Q9HD20,P61421,Q7KZN9,O75306,P20674
Functions
GO Molecular function
msigdb_gomf
515,14,15,26,286,408,295,170,426,305,447,322,204,341,219,120,348,364,244,504
856,15,727,872,244,1924,858,1289,1598,426,305,26,295,751,322,1006,1291,286,547,2225,170,504,877,2404,740,2693,807,515,2182,408,2559,769,348,447,219,1057,1307,364,120,2671,204,14,973,341
0.1905477242530135,3.4199522827989974,0.332688904231155,0.17611273471205496,1.3586851022140123,-0.5036894974780469,0.1905477242530135,-0.13692690238543065,-0.3089938532666943,0.78839669765801,1.147599572470142,3.105839691433299,1.1714797320050525,0.30457623372576403,1.087415425314427,0.07390195373379957,-0.13692690238543065,1.2189142308211247,0.5656005771908399,-0.6890863348428883,1.6710149037139495,0.632136528586786,0.17611273471205496,-0.8638509468356808,0.3186519434677123,-2.0224789299810415,0.2478813025768698,0.6188981125431084,-0.6548601180580003,0.826732699034428,-1.1006945383567346,0.29046154644551864,0.9896472724402028,0.7497737515679389,1.4611164567099202,0.029458532651360454,-0.13692690238543065,0.9525040135933169,2.0066948267496136,-1.5704713475646683,1.5394252878937733,3.427774762153474,0.10331578012873843,1.0265264066984594
2,719
Cilium assembly
23
56
2.450415
0.014269
P62258,Q96KP1,O43924,Q10713,O94927,Q15691,Q15051,O43805,Q14203,A6NIH7,Q13561,Q96CS2,Q9H6D7,Q9Y496,P41208,P30153,Q92973,O75935,O00471,P63167,A0AVF1,P04350,Q8NCM8
Processes and pathways
Reactome Pathways
msigdb_reactome
640,645,21,540,165,306,440,310,568,63,705,200,329,723,457,589,90,464,598,479,223,610,382
223,63,598,310,21,1214,464,165,805,610,1072,1320,1133,1627,1798,1323,589,1738,457,1243,1360,2154,1875,1903,1461,1607,1421,1327,640,479,987,1508,540,1303,705,1054,2503,568,2433,1024,440,306,1582,382,2195,1279,90,200,1561,645,1103,1065,1977,329,722,723
1.4385262761005175,2.5750940135788953,0.49819048944279026,1.1356182999373312,3.293254641370149,-0.09100256702323781,0.6978221404482146,1.7141580813590667,0.2478813025768698,0.4846014092491796,0.014556932935040613,-0.15232845914399104,-0.030413098045804464,-0.32493250526949763,-0.421643782078971,-0.15232845914399104,0.5117436144293259,-0.38919874485326694,0.723863433268658,-0.10626425831084813,-0.1677772467277911,-0.6378349653375106,-0.47070938318962924,-0.48717221640031005,-0.2144101059765268,-0.3089938532666943,-0.19881775585569805,-0.15232845914399104,0.44361639063605623,0.6847519362737263,0.08863020155351369,-0.24574059272730153,0.5923184989479339,-0.13692690238543065,0.3606474828614861,0.029458532651360454,-0.9899664782882975,0.5387428051993683,-0.8995564994467704,0.05913077172037472,0.7626802321711698,1.147599572470142,-0.2931056735100328,0.8900005618991303,-0.6548601180580003,-0.12157226993528147,2.2646396892872667,1.5615865779228295,-0.2772676267666931,0.44361639063605623,-0.00038868636313022414,0.029458532651360454,-0.5202616114390414,1.0631453851685053,0.34668734253092304,0.34668734253092304
2,719
Steroid metabolic process
17
63
2.448354
0.014351
Q13510,Q06520,P04062,P38435,O75845,P16435,Q14739,Q8WTV0,O15118,O76054,Q15392,Q14849,Q15800,O95470,Q16850,Q53GQ0,Q9BQE5
Processes and pathways
GO Biological process
msigdb_gobp
35,5,71,139,203,238,207,110,273,148,52,87,23,93,154,251,29
778,273,203,148,1762,93,1625,71,295,2580,1601,1092,2151,238,2251,1137,1933,2532,740,1020,2597,139,2636,2501,1359,2209,2130,851,2227,2302,446,2323,2631,882,5,35,2577,207,87,1555,2436,52,2660,2643,23,154,251,915,885,773,110,2645,1396,2604,29,1588,1699,1233,1672,2473,935,345,1049
0.2763076509973368,1.2542091223510612,1.5394252878937733,1.8624446742934746,-0.4053949717396913,2.245234151230295,-0.32493250526949763,2.5107215183813394,1.1714797320050525,-1.1570079553072803,-0.3089938532666943,-0.00038868636313022414,-0.6378349653375106,1.3816213018328303,-0.7062882632563935,-0.030413098045804464,-0.5036894974780469,-1.0450191132829518,0.3186519434677123,0.05913077172037472,-1.213975141317416,1.9040605759318283,-1.3299369864356707,-0.9899664782882975,-0.1677772467277911,-0.6719437646434965,-0.620867881511793,0.20494183108481331,-0.6890863348428883,-0.7582546181179882,0.7497737515679389,-0.7756984250375901,-1.31041805381167,0.17611273471205496,3.7466882849921066,2.971565848245718,-1.138164966594554,1.5060072044287904,2.3128479941750375,-0.2772676267666931,-0.8995564994467704,2.74604529197796,-1.4688005294598216,-1.3495342310278062,3.2287919262177374,1.7888209300317397,1.335647955135846,0.1471191126541989,0.17611273471205496,0.29046154644551864,2.1471356130946906,-1.3495342310278062,-0.18327357472878134,-1.213975141317416,3.055873620168304,-0.2931056735100328,-0.3569626006240997,-0.09100256702323781,-0.3409219722772057,-0.9355219790549657,0.13255997690276794,1.014262462244214,0.04431638803769443
2,719
Hydrolase activity hydrolyzing o glycosyl compounds
8
19
2.448118
0.01436
Q9BTY2,P06280,P04062,P17900,P16278,O60476,P06865,Q9NUJ1
Functions
GO Molecular function
msigdb_gomf
194,226,71,135,206,80,177,190
80,521,71,1034,226,177,1818,380,206,135,752,264,1635,2305,1946,655,194,190,2651
2.370131263440487,0.6056254989038173,2.5107215183813394,0.04431638803769443,1.4271945957883734,1.6275159466122078,-0.43794554085718024,0.8900005618991303,1.5060072044287904,1.9247467241533158,0.30457623372576403,1.2776071666564428,-0.32493250526949763,-0.7582546181179882,-0.5036894974780469,0.4298814338746595,1.5836549017230799,1.605631086088607,-1.428719909350296
2,719
Glycosidase
7
15
2.44118
0.014639
Q9BTY2,P06280,P04062,P54802,P16278,O60476,P06865
Functions
Protein Atlas Molecular function
protein_atlas_molecular_function
194,226,71,264,206,80,177
635,80,521,71,1034,226,177,1818,380,206,752,264,2305,1946,194
0.44361639063605623,2.370131263440487,0.6056254989038173,2.5107215183813394,0.04431638803769443,1.4271945957883734,1.6275159466122078,-0.43794554085718024,0.8900005618991303,1.5060072044287904,0.30457623372576403,1.2776071666564428,-0.7582546181179882,-0.5036894974780469,1.5836549017230799
2,719
Regulation of cellular ph
7
16
2.437556
0.014787
P51790,O75503,Q9Y487,Q15904,Q8N511,P50897,P61421
Processes and pathways
GO Biological process
msigdb_gobp
261,231,395,240,48,24,348
231,751,1653,1770,24,1297,261,348,240,48,401,644,1178,973,395,2608
1.404457491582026,0.30457623372576403,-0.3409219722772057,-0.4053949717396913,3.1471316821409943,-0.13692690238543065,1.289267000376432,0.9896472724402028,1.3701657615426401,2.763729779838205,0.8521328477933847,0.44361639063605623,-0.04549245437206825,0.10331578012873843,0.8647862588625002,-1.213975141317416
2,719
Regulation of ph
7
16
2.437556
0.014787
P51790,O75503,Q9Y487,Q15904,Q8N511,P50897,P61421
Processes and pathways
GO Biological process
msigdb_gobp
261,231,395,240,48,24,348
231,751,1653,1770,24,1297,261,348,240,48,401,644,1178,973,395,2608
1.404457491582026,0.30457623372576403,-0.3409219722772057,-0.4053949717396913,3.1471316821409943,-0.13692690238543065,1.289267000376432,0.9896472724402028,1.3701657615426401,2.763729779838205,0.8521328477933847,0.44361639063605623,-0.04549245437206825,0.10331578012873843,0.8647862588625002,-1.213975141317416
2,719
Respiratory chain
10
28
2.432268
0.015005
Q96CU9,O14949,Q9P0J0,Q9UDW1,O43676,P00403,O75306,Q6DKK2,P03886,P47985
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
39,72,204,14,15,305,244,118,26,408
856,72,15,872,244,1924,858,1289,1598,426,305,26,1006,2317,2225,638,2693,807,408,2559,769,1057,1307,118,39,608,204,14
0.1905477242530135,2.4828960163826035,3.4199522827989974,0.17611273471205496,1.3586851022140123,-0.5036894974780469,0.1905477242530135,-0.13692690238543065,-0.3089938532666943,0.78839669765801,1.147599572470142,3.105839691433299,0.07390195373379957,-0.7756984250375901,-0.6890863348428883,0.44361639063605623,-2.0224789299810415,0.2478813025768698,0.826732699034428,-1.1006945383567346,0.29046154644551864,0.029458532651360454,-0.13692690238543065,2.04720003960902,2.894556239112553,0.49819048944279026,1.5394252878937733,3.427774762153474
2,719
Microbody membrane
9
24
2.431538
0.015035
O75381,Q6IAN0,Q9BY49,O00116,Q15067,Q9NR77,Q96HA9,P40855,P51648
Localization
GO Cellular component
msigdb_gocc
417,387,561,218,558,253,91,317,64
218,600,980,417,1182,1712,740,1111,1773,317,64,851,558,387,817,866,948,1170,91,1028,1588,561,253,830
1.4611164567099202,0.49819048944279026,0.08863020155351369,0.8139856344410125,-0.0606169582349026,-0.37305474027032975,0.3186519434677123,-0.015378603154741318,-0.4053949717396913,1.111572693459288,2.5750940135788953,0.20494183108481331,0.552189269880853,0.8774087768247075,0.2478813025768698,0.1905477242530135,0.11795895191442474,-0.04549245437206825,2.2549457173407865,0.05913077172037472,-0.2931056735100328,0.552189269880853,1.3125089094881686,0.23360837776605786
2,719
Airway obstruction
6
12
2.42231
0.015422
P06280,P09601,P21964,P16435,O75844,Q86Y56
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
226,40,171,238,82,153
82,1354,226,40,238,171,2185,2435,153,1064,644,356
2.3511047492659554,-0.1677772467277911,1.4271945957883734,2.859976400730297,1.3816213018328303,1.6710149037139495,-0.6548601180580003,-0.8995564994467704,1.8310169016228028,0.029458532651360454,0.44361639063605623,0.9772957319876318
2,719
transfer/carrier protein
6
9
2.419864
0.015526
P17900,P05141,P12236,Q9Y5M8,P12235,O15127
Functions
Panther Protein class
panther_protein_class
135,327,143,119,186,59
454,59,1963,327,186,143,135,1137,119
0.723863433268658,2.6024486449078035,-0.5202616114390414,1.0631453851685053,1.605631086088607,1.8832934520415403,1.9247467241533158,-0.030413098045804464,2.037102603070871
2,719
Transmembrane transport
82
184
2.417712
0.015618
P36543,Q99595,Q9NS69,P21796,Q9H2D1,Q9UDW1,O60830,P45880,Q9UHG3,O75964,Q9UBX3,Q9Y4C2,Q9C0H2,O14925,Q96H78,P04062,Q70HW3,Q8TB61,Q9UGP8,O75844,Q15629,O60831,P24539,Q8WTV0,Q9HD20,Q6P4Q7,Q9Y619,P38435,P12236,Q9Y277,Q96QD8,P78417,Q5T1Q4,P20020,P12235,P62942,Q99797,Q6P4A7,Q15388,Q9BSK2,P07384,Q9UJS0,P51790,Q8NHS3,P52789,Q9BZF1,P13073,P05023,Q96ES6,Q6NUK1,O75298,P00403,Q9HD26,Q9BQT8,P08183,O95202,P05141,Q9H9B4,P56385,P61421,Q99523,Q7KZN9,Q07820,L0R6Q1,O43615,Q15043,O75915,Q06787,P47985,O75381,P49840,O43772,Q03518,O75746,Q8IXU6,Q96PU5,P55011,O95831,P23786,Q6ZWJ1,P49755,P20674
Processes and pathways
GO Biological process
msigdb_gobp
515,6,11,12,13,14,19,22,28,34,38,47,49,54,70,71,76,78,79,82,96,95,98,110,120,122,125,139,143,146,147,162,169,170,186,187,201,210,219,221,249,262,261,270,278,281,286,295,300,299,303,305,308,311,322,326,327,334,336,348,365,364,377,375,379,386,383,409,408,417,432,437,447,449,461,474,471,465,478,486,495,504
375,1452,2067,856,2040,54,379,726,437,600,979,2041,19,95,727,2246,872,303,513,417,1265,449,82,383,804,34,628,326,465,609,305,71,295,327,1650,751,2071,249,2103,322,806,1006,1036,1291,2430,1601,186,143,286,547,1627,170,504,877,2404,2575,12,478,98,2476,2075,740,1485,1604,807,1111,2368,794,515,139,2182,1385,1459,22,878,408,2520,495,432,629,1185,261,278,781,823,1114,471,852,336,1462,2156,348,1715,640,187,162,566,1366,2132,677,447,882,1717,409,1391,377,2422,695,1304,1743,1202,759,883,386,2390,219,96,864,732,1780,714,169,299,2337,210,122,486,76,364,2114,2138,461,799,2395,989,270,78,2264,110,2454,844,300,70,2235,646,474,147,1282,2470,365,6,593,201,1230,311,1151,221,1256,2528,281,49,13,1400,334,1401,120,308,2671,11,38,14,79,1178,28,973,262,1087,937,146,1380,47,1316,125,2608
0.9025617730365805,-0.2144101059765268,-0.587106244130671,0.1905477242530135,-0.5703108638932032,2.6657421041309006,0.8900005618991303,0.332688904231155,0.7626802321711698,0.49819048944279026,0.08863020155351369,-0.5703108638932032,3.317234140715181,2.22575796347679,0.332688904231155,-0.7062882632563935,0.17611273471205496,1.147599572470142,0.6188981125431084,0.8139856344410125,-0.12157226993528147,0.736834876495512,2.3511047492659554,0.8774087768247075,0.2478813025768698,2.971565848245718,0.457314566306333,1.0631453851685053,0.6978221404482146,0.4846014092491796,1.147599572470142,2.5107215183813394,1.1714797320050525,1.0631453851685053,-0.3409219722772057,0.30457623372576403,-0.587106244130671,1.3471792062317862,-0.6039584463179856,1.087415425314427,0.2478813025768698,0.07390195373379957,0.04431638803769443,-0.13692690238543065,-0.8995564994467704,-0.3089938532666943,1.605631086088607,1.8832934520415403,1.2189142308211247,0.5656005771908399,-0.32493250526949763,1.6710149037139495,0.632136528586786,0.17611273471205496,-0.8638509468356808,-1.138164966594554,3.451175716066335,0.6847519362737263,2.215993204297903,-0.9536034576855446,-0.587106244130671,0.3186519434677123,-0.23005094416154934,-0.3089938532666943,0.2478813025768698,-0.015378603154741318,-0.8284013522129561,0.26211431465637414,0.6188981125431084,1.9040605759318283,-0.6548601180580003,-0.18327357472878134,-0.2144101059765268,3.253054371219224,0.17611273471205496,0.826732699034428,-1.0265997707300218,0.6453409341751739,0.7755544905767453,0.457314566306333,-0.0606169582349026,1.289267000376432,1.2424706616319041,0.2763076509973368,0.23360837776605786,-0.015378603154741318,0.6978221404482146,0.20494183108481331,1.0265264066984594,-0.2144101059765268,-0.6378349653375106,0.9896472724402028,-0.37305474027032975,0.44361639063605623,1.605631086088607,1.7355981785016048,0.5387428051993683,-0.1677772467277911,-0.620867881511793,0.402300331182603,0.7497737515679389,0.17611273471205496,-0.37305474027032975,0.826732699034428,-0.18327357472878134,0.9025617730365805,-0.8816714825203786,0.37456954772114676,-0.13692690238543065,-0.38919874485326694,-0.07578689853775272,0.30457623372576403,0.17611273471205496,0.8774087768247075,-0.8460943992105768,1.4611164567099202,2.22575796347679,0.1905477242530135,0.332688904231155,-0.4053949717396913,0.34668734253092304,1.6818338097384962,1.1595533384376537,-0.7932038385838693,1.494820444712504,1.98632596881489,0.671648454750572,2.436197942025277,0.9525040135933169,-0.6039584463179856,-0.620867881511793,0.7108592467728196,0.26211431465637414,-0.8460943992105768,0.08863020155351369,1.2659212488513751,2.379619278698563,-0.7062882632563935,2.1471356130946906,-0.9175064966386184,0.2192953010576298,1.1595533384376537,2.5199648159717087,-0.6890863348428883,0.44361639063605623,0.6978221404482146,1.8728793126258834,-0.12157226993528147,-0.9355219790549657,0.9525040135933169,3.7466882849921066,0.5117436144293259,1.5615865779228295,-0.09100256702323781,1.1356182999373312,-0.030413098045804464,1.4498335257671533,-0.10626425831084813,-1.0265997707300218,1.2424706616319041,2.763729779838205,3.4433864453496845,-0.18327357472878134,1.038761445699194,-0.18327357472878134,2.0066948267496136,1.147599572470142,-1.5704713475646683,3.474477642713755,2.911763976530236,3.427774762153474,2.379619278698563,-0.04549245437206825,3.0892351012046553,0.10331578012873843,1.289267000376432,0.014556932935040613,0.13255997690276794,1.8832934520415403,-0.1677772467277911,2.7725504193892325,-0.13692690238543065,1.965878763574573,-1.213975141317416
2,719
Amyloid precursor protein metabolic process
9
18
2.414818
0.015743
Q92542,O95197,Q9NQC3,O75298,P49840,Q15392,Q9NQX7,P62942,P10909
Processes and pathways
GO Biological process
msigdb_gobp
453,43,109,303,432,52,214,187,466
832,303,43,466,2075,495,432,187,1906,1526,1203,52,453,1280,1562,109,214,2565
0.2192953010576298,1.147599572470142,2.798926517414969,0.6978221404482146,-0.587106244130671,0.6453409341751739,0.7755544905767453,1.605631086088607,-0.48717221640031005,-0.2614793772811411,-0.07578689853775272,2.74604529197796,0.736834876495512,-0.12157226993528147,-0.2772676267666931,2.157026937488641,1.483609806203434,-1.1006945383567346
2,719
Hand polydactyly
13
24
2.410925
0.015912
O60826,Q8NCM8,Q9BXW9,O96028,O95202,P21964,O75845,Q14739,Q15067,O43924,Q13045,Q10713,Q9UHX1
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
416,382,584,166,326,171,203,207,558,21,473,540,130
21,416,203,326,166,2575,171,1738,2185,579,540,927,473,1578,207,2083,558,382,1064,1977,584,1672,130,1048
3.293254641370149,0.8139856344410125,1.5394252878937733,1.0631453851685053,1.7034053026076874,-1.138164966594554,1.6710149037139495,-0.38919874485326694,-0.6548601180580003,0.5252609862464442,0.5923184989479339,0.13255997690276794,0.6978221404482146,-0.2931056735100328,1.5060072044287904,-0.587106244130671,0.552189269880853,0.8900005618991303,0.029458532651360454,-0.5202616114390414,0.5252609862464442,-0.3409219722772057,1.945352566311608,0.04431638803769443
2,719
Molecular transducer activity
10
30
2.406423
0.01611
Q14108,Q15629,Q99720,O15173,Q99523,Q8WTV0,Q9UGP8,O15118,Q9BUN8,Q08722
Functions
GO Molecular function
msigdb_gomf
193,96,36,107,365,110,79,273,116,188
376,273,107,1678,1650,1682,956,467,1487,603,591,1466,188,1274,193,96,864,642,2084,2649,110,707,2454,1282,365,36,116,1756,1177,79
0.9025617730365805,1.2542091223510612,2.1767547750820517,-0.3569626006240997,-0.3409219722772057,-0.3569626006240997,0.10331578012873843,0.6978221404482146,-0.23005094416154934,0.49819048944279026,0.5117436144293259,-0.2144101059765268,1.605631086088607,-0.12157226993528147,1.5836549017230799,2.22575796347679,0.1905477242530135,0.44361639063605623,-0.587106244130671,-1.428719909350296,2.1471356130946906,0.3606474828614861,-0.9175064966386184,-0.12157226993528147,0.9525040135933169,2.946016924906694,2.087399401896311,-0.38919874485326694,-0.04549245437206825,2.379619278698563
2,719
Secretory granule membrane
21
58
2.399624
0.016412
P35613,Q9NZJ7,Q93050,Q5T9A4,P30519,P07602,P10321,Q08722,Q92542,Q15363,O15260,O00264,Q07065,Q9Y5K8,Q9NQX7,P63167,P61026,P42785,Q8NF37,Q969Q5,P10253
Localization
GO Cellular component
msigdb_gocc
263,265,401,284,30,168,312,188,453,69,330,335,211,341,214,479,492,117,373,378,380
2222,335,330,2041,1214,2247,2400,2042,168,380,312,1292,956,2678,1160,1094,1548,30,1604,1629,263,1199,117,1853,495,1361,1297,2386,1270,492,1364,1740,986,479,2132,211,2701,188,1658,1329,1203,69,2632,284,915,373,826,453,401,378,1752,1232,1174,214,265,1404,341,1480
-0.6890863348428883,1.0265264066984594,1.0509677239800752,-0.5703108638932032,-0.09100256702323781,-0.7062882632563935,-0.8638509468356808,-0.5703108638932032,1.69263057727874,0.8900005618991303,1.123609385664931,-0.13692690238543065,0.10331578012873843,-1.6743177601757857,-0.04549245437206825,-0.00038868636313022414,-0.2772676267666931,3.0475012788562985,-0.3089938532666943,-0.32493250526949763,1.2776071666564428,-0.07578689853775272,2.07737796601851,-0.4543006169521521,0.6453409341751739,-0.1677772467277911,-0.13692690238543065,-0.8460943992105768,-0.12157226993528147,0.6585115148857332,-0.1677772467277911,-0.38919874485326694,0.08863020155351369,0.6847519362737263,-0.620867881511793,1.483609806203434,-2.3979222331766588,1.605631086088607,-0.3409219722772057,-0.15232845914399104,-0.07578689853775272,2.5199648159717087,-1.31041805381167,1.2307057402478268,0.1471191126541989,0.9150925679330987,0.23360837776605786,0.736834876495512,0.8521328477933847,0.9025617730365805,-0.38919874485326694,-0.09100256702323781,-0.04549245437206825,1.483609806203434,1.2776071666564428,-0.18327357472878134,1.0265264066984594,-0.2144101059765268
2,719
Cytochrome complex
7
17
2.385738
0.017045
O14949,P14406,Q9UDW1,Q7KZN9,P00403,P13073,P47985
Localization
GO Cellular component
msigdb_gocc
72,73,14,364,305,286,408
856,72,305,1006,1796,1291,286,73,2317,1602,504,638,807,408,364,14,1235
0.1905477242530135,2.4828960163826035,1.147599572470142,0.07390195373379957,-0.421643782078971,-0.13692690238543065,1.2189142308211247,2.4828960163826035,-0.7756984250375901,-0.3089938532666943,0.632136528586786,0.44361639063605623,0.2478813025768698,0.826732699034428,0.9525040135933169,3.427774762153474,-0.09100256702323781
2,719
Endoplasmic reticulum protein containing complex
22
57
2.378552
0.017381
P13674,O15269,O43681,Q6NUQ1,Q9BV81,P67812,Q15005,Q9UBV2,P62942,P14625,Q03518,Q9NPA0,Q9UGP8,Q5J8M3,Q8TCT9,Q9BUN8,P46977,Q9Y5M8,O43292,P51571,Q53GQ0,Q9UBU6
Localization
GO Cellular component
msigdb_gocc
384,260,389,145,541,152,283,173,187,443,447,463,79,337,498,116,245,119,248,506,251,255
2690,260,1070,1546,248,1481,389,1457,873,1711,728,384,1651,443,2299,2367,2349,1199,245,539,506,2228,1462,1551,1715,1997,187,152,447,1426,1329,1946,283,839,2614,251,337,145,1694,1862,867,498,688,1064,1698,691,1281,116,541,463,255,173,79,1840,2506,119,831
-1.9330494440790569,1.289267000376432,0.014556932935040613,-0.2772676267666931,1.3471792062317862,-0.23005094416154934,0.8647862588625002,-0.2144101059765268,0.17611273471205496,-0.37305474027032975,0.332688904231155,0.8774087768247075,-0.3409219722772057,0.7497737515679389,-0.7582546181179882,-0.8284013522129561,-0.8107713240707701,-0.07578689853775272,1.3586851022140123,0.5923184989479339,0.632136528586786,-0.6890863348428883,-0.2144101059765268,-0.2772676267666931,-0.37305474027032975,-0.5368889474821656,1.605631086088607,1.8310169016228028,0.7497737515679389,-0.19881775585569805,-0.15232845914399104,-0.5036894974780469,1.2307057402478268,0.2192953010576298,-1.233112298811929,1.335647955135846,1.0265264066984594,1.8832934520415403,-0.3569626006240997,-0.4543006169521521,0.1905477242530135,0.6453409341751739,0.38845375763582707,0.029458532651360454,-0.3569626006240997,0.38845375763582707,-0.12157226993528147,2.087399401896311,0.5923184989479339,0.7108592467728196,1.3125089094881686,1.6710149037139495,2.379619278698563,-0.43794554085718024,-0.9899664782882975,2.037102603070871,0.23360837776605786
2,719
Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins
15
55
2.366003
0.017981
Q9NPL8,P24539,O75964,O14949,Q16134,Q9P0J0,Q9UDW1,O43676,O96000,P00403,P56385,O75306,P03886,P13073,P47985
Processes and pathways
Reactome Pathways
msigdb_reactome
352,98,34,72,42,204,14,15,426,305,336,244,26,286,408
856,72,15,511,872,244,1924,651,804,34,858,1289,1598,426,305,26,751,1006,1796,1291,286,2518,2317,1602,2225,504,444,638,98,2476,2693,1714,807,794,2301,1852,408,2520,2559,769,852,336,1803,42,1057,1307,774,1151,890,1956,352,608,1175,204,14
0.1905477242530135,2.4828960163826035,3.4199522827989974,0.6188981125431084,0.17611273471205496,1.3586851022140123,-0.5036894974780469,0.4298814338746595,0.2478813025768698,2.971565848245718,0.1905477242530135,-0.13692690238543065,-0.3089938532666943,0.78839669765801,1.147599572470142,3.105839691433299,0.30457623372576403,0.07390195373379957,-0.421643782078971,-0.13692690238543065,1.2189142308211247,-1.0265997707300218,-0.7756984250375901,-0.3089938532666943,-0.6890863348428883,0.632136528586786,0.7497737515679389,0.44361639063605623,2.215993204297903,-0.9536034576855446,-2.0224789299810415,-0.37305474027032975,0.2478813025768698,0.26211431465637414,-0.7582546181179882,-0.4543006169521521,0.826732699034428,-1.0265997707300218,-1.1006945383567346,0.29046154644551864,0.20494183108481331,1.0265264066984594,-0.421643782078971,2.807690107486791,0.029458532651360454,-0.13692690238543065,0.29046154644551864,-0.030413098045804464,0.17611273471205496,-0.5036894974780469,0.9896472724402028,0.49819048944279026,-0.04549245437206825,1.5394252878937733,3.427774762153474
2,719
Translocation
14
46
2.354384
0.018553
Q15629,O75381,O75694,Q8NFH5,Q99595,P41208,P62072,Q9NS69,O60830,O14925,O43615,Q9BTX1,Q8NFH4,Q8N1F7
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
96,417,161,132,6,457,10,11,19,54,379,92,350,287
2244,54,379,19,417,161,1765,1504,2126,457,2078,1937,1200,472,1462,1715,551,10,1143,1145,96,714,2334,2391,2569,1010,287,350,132,1192,2116,2089,905,1026,1282,1563,6,92,2623,2310,1375,11,1177,2037,1088,2672
-0.7062882632563935,2.6657421041309006,0.8900005618991303,3.317234140715181,0.8139856344410125,1.7355981785016048,-0.4053949717396913,-0.24574059272730153,-0.620867881511793,0.723863433268658,-0.587106244130671,-0.5036894974780469,-0.07578689853775272,0.6978221404482146,-0.2144101059765268,-0.37305474027032975,0.5656005771908399,3.4899576845407503,-0.030413098045804464,-0.030413098045804464,2.22575796347679,0.34668734253092304,-0.7932038385838693,-0.8460943992105768,-1.119394022350341,0.07390195373379957,1.2189142308211247,0.9896472724402028,1.9350596419712964,-0.0606169582349026,-0.6039584463179856,-0.587106244130671,0.16163661432793977,0.05913077172037472,-0.12157226993528147,-0.2772676267666931,3.7466882849921066,2.2549457173407865,-1.2716124786728344,-0.7582546181179882,-0.1677772467277911,3.474477642713755,-0.04549245437206825,-0.5535718990503548,0.014556932935040613,-1.5704713475646683
2,719
Duplication involving bones of the feet
6
17
2.348646
0.018842
O96028,O95202,P21964,O75845,Q14739,O43924
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
166,326,171,203,207,21
21,203,750,326,166,171,1738,2185,540,1578,207,1062,382,1064,2141,1672,1048
3.293254641370149,1.5394252878937733,0.30457623372576403,1.0631453851685053,1.7034053026076874,1.6710149037139495,-0.38919874485326694,-0.6548601180580003,0.5923184989479339,-0.2931056735100328,1.5060072044287904,0.029458532651360454,0.8900005618991303,0.029458532651360454,-0.620867881511793,-0.3409219722772057,0.04431638803769443
2,719
Electron transport
15
42
2.343053
0.019127
Q96CU9,P47985,O14949,Q16134,Q9P0J0,Q9UDW1,O43676,O96000,P00403,O43169,O75306,Q6DKK2,Q9H3N1,P03886,Q9H1E5
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
39,408,72,42,204,14,15,426,305,50,244,118,414,26,159
856,72,50,1706,15,872,244,1924,858,1289,1598,490,426,305,26,1006,2518,2317,2225,444,1933,638,2693,1714,807,2368,2301,408,2559,769,42,1057,1307,2525,118,39,2235,159,414,608,204,14
0.1905477242530135,2.4828960163826035,2.7548947540582653,-0.37305474027032975,3.4199522827989974,0.17611273471205496,1.3586851022140123,-0.5036894974780469,0.1905477242530135,-0.13692690238543065,-0.3089938532666943,0.6585115148857332,0.78839669765801,1.147599572470142,3.105839691433299,0.07390195373379957,-1.0265997707300218,-0.7756984250375901,-0.6890863348428883,0.7497737515679389,-0.5036894974780469,0.44361639063605623,-2.0224789299810415,-0.37305474027032975,0.2478813025768698,-0.8284013522129561,-0.7582546181179882,0.826732699034428,-1.1006945383567346,0.29046154644551864,2.807690107486791,0.029458532651360454,-0.13692690238543065,-1.0265997707300218,2.04720003960902,2.894556239112553,-0.6890863348428883,1.7569516212052485,0.826732699034428,0.49819048944279026,1.5394252878937733,3.427774762153474
2,719
Carbohydrate derivative catabolic process
10
31
2.334232
0.019584
Q9BTY2,Q9H773,P06280,P17900,P04062,P16278,P06865,Q13126,Q9BW91,Q9NUJ1
Processes and pathways
GO Biological process
msigdb_gobp
194,164,226,135,71,206,177,18,184,190
1593,521,2347,1847,71,1034,226,177,1818,847,822,206,135,2532,1899,1994,1525,432,2210,264,18,2395,1665,1888,194,184,2455,164,190,1980,1451
-0.3089938532666943,0.6056254989038173,-0.8107713240707701,-0.4543006169521521,2.5107215183813394,0.04431638803769443,1.4271945957883734,1.6275159466122078,-0.43794554085718024,0.20494183108481331,0.23360837776605786,1.5060072044287904,1.9247467241533158,-1.0450191132829518,-0.48717221640031005,-0.5368889474821656,-0.2614793772811411,0.7755544905767453,-0.6719437646434965,1.2776071666564428,3.325204081162159,-0.8460943992105768,-0.3409219722772057,-0.47070938318962924,1.5836549017230799,1.6165848812880583,-0.9175064966386184,1.7248890085329789,1.605631086088607,-0.5202616114390414,-0.19881775585569805
2,719
Phospholipid biosynthesis
9
12
2.334176
0.019587
Q96N66,Q96JX3,Q9UG56,Q99943,P48651,Q8NF37,P35790,O95674,Q9NUQ2
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
127,289,235,666,277,373,60,601,519
601,60,277,885,373,690,289,127,666,1700,519,235
0.49819048944279026,2.6024486449078035,1.2424706616319041,0.17611273471205496,0.9150925679330987,0.38845375763582707,1.195250933615223,1.945352566311608,0.41610948501277006,-0.3569626006240997,0.6188981125431084,1.3930518398628324
2,719
Inorganic anion transmembrane transporter activity
8
14
2.330631
0.019773
Q15043,Q9UBX3,P51790,O43681,P21796,Q9C0H2,Q9Y277,P45880
Functions
GO Molecular function
msigdb_gomf
386,38,261,389,12,49,146,22
2067,389,12,22,261,471,677,386,2542,709,49,38,146,2608
-0.587106244130671,0.8647862588625002,3.451175716066335,3.253054371219224,1.289267000376432,0.6978221404482146,0.402300331182603,0.8774087768247075,-1.0635076502293486,0.3606474828614861,2.763729779838205,2.911763976530236,1.8832934520415403,-1.213975141317416
2,719
Protein targeting
39
100
2.329587
0.019828
Q9Y371,P51572,Q99595,P62072,Q9NS69,O43681,O60830,Q10713,Q15005,O75381,P43307,Q9Y4C2,P49840,Q5JRX3,O14925,P40855,P57105,P46379,Q14108,Q99797,Q9P0J0,O60725,Q9UGP8,Q9UBE0,P49257,O95831,Q15388,P10909,P20645,Q16543,Q15629,Q6ZWJ1,Q8N4H5,Q99523,P55786,Q9Y512,O14737,Q9Y5M8,O43615
Processes and pathways
GO Biological process
msigdb_gobp
520,385,6,10,11,389,19,540,283,417,37,47,432,53,54,317,445,191,193,201,204,77,79,340,470,465,219,466,467,97,96,486,104,365,491,502,368,119,379
2244,1621,2147,1760,368,54,953,563,379,389,1002,77,19,417,1265,2428,628,941,465,609,1133,1989,2430,466,1240,1896,467,1184,2075,2025,684,2076,1574,317,37,191,470,539,432,1297,385,491,445,1462,1551,2156,1715,1327,10,640,1942,925,2111,1366,540,695,193,283,219,96,2232,97,714,1393,53,486,2699,1010,1911,2292,2114,1809,104,948,1282,365,1954,6,201,2168,2312,1401,1045,11,2144,204,340,79,648,1178,998,2457,667,668,520,830,47,502,2672,119
-0.7062882632563935,-0.32493250526949763,-0.6378349653375106,-0.4053949717396913,0.9400635335930252,2.6657421041309006,0.10331578012873843,0.5387428051993683,0.8900005618991303,0.8647862588625002,0.07390195373379957,2.379619278698563,3.317234140715181,0.8139856344410125,-0.12157226993528147,-0.8995564994467704,0.457314566306333,0.11795895191442474,0.6978221404482146,0.4846014092491796,-0.030413098045804464,-0.5368889474821656,-0.8995564994467704,0.6978221404482146,-0.10626425831084813,-0.48717221640031005,0.6978221404482146,-0.0606169582349026,-0.587106244130671,-0.5535718990503548,0.38845375763582707,-0.587106244130671,-0.2931056735100328,1.111572693459288,2.9203474611613784,1.594654460100512,0.6978221404482146,0.5923184989479339,0.7755544905767453,-0.13692690238543065,0.8774087768247075,0.6585115148857332,0.7497737515679389,-0.2144101059765268,-0.2772676267666931,-0.6378349653375106,-0.37305474027032975,-0.15232845914399104,3.4899576845407503,0.44361639063605623,-0.5036894974780469,0.13255997690276794,-0.6039584463179856,-0.1677772467277911,0.5923184989479339,0.37456954772114676,1.5836549017230799,1.2307057402478268,1.4611164567099202,2.22575796347679,-0.6890863348428883,2.22575796347679,0.34668734253092304,-0.18327357472878134,2.701579665755794,0.671648454750572,-2.2773891393535837,0.07390195373379957,-0.48717221640031005,-0.7408719578287188,-0.6039584463179856,-0.421643782078971,2.1964100084149285,0.11795895191442474,-0.12157226993528147,0.9525040135933169,-0.5036894974780469,3.7466882849921066,1.5615865779228295,-0.6378349653375106,-0.7582546181179882,-0.18327357472878134,0.04431638803769443,3.474477642713755,-0.620867881511793,1.5394252878937733,1.0265264066984594,2.379619278698563,0.44361639063605623,-0.04549245437206825,0.08863020155351369,-0.9175064966386184,0.41610948501277006,0.41610948501277006,0.6188981125431084,0.23360837776605786,2.7725504193892325,0.6453409341751739,-1.5704713475646683,2.037102603070871
2,719
Nucleocytoplasmic carrier activity
10
19
2.327935
0.019916
Q9Y5L0,O00505,Q8TEX9,O60684,Q9HAV4,O00410,O60518,Q92973,P52294,Q14974
Functions
GO Molecular function
msigdb_gomf
546,325,133,455,499,402,438,90,220,349
402,325,2474,1793,438,455,1504,1606,220,835,1188,349,133,90,1280,585,499,1031,546
0.8394483821163174,1.0631453851685053,-0.9536034576855446,-0.421643782078971,0.7626802321711698,0.723863433268658,-0.24574059272730153,-0.3089938532666943,1.4498335257671533,0.2192953010576298,-0.0606169582349026,0.9896472724402028,1.9350596419712964,2.2646396892872667,-0.12157226993528147,0.5252609862464442,0.6453409341751739,0.05913077172037472,0.5789769223558233
2,719
Tclin
16
75
2.321421
0.020264
P49721,Q99720,P06280,Q9P0J0,P38435,P21964,O43676,P00374,Q16739,O75306,O43924,P31350,P20618,P03886,P62942,Q06203
Drugs and Diseases
Pharos IDG Category
pharos_protein_category
67,36,226,204,139,171,15,16,83,244,21,150,149,26,187,252
856,15,21,832,872,244,1924,858,1289,1598,426,16,2567,2347,26,610,576,295,1817,1650,226,1320,2072,2045,1036,380,2046,2417,2634,683,1712,1092,2151,2225,149,693,171,2318,2319,739,1037,523,2693,1138,150,1773,139,913,796,67,2559,432,2321,769,1114,471,187,987,881,252,1511,1368,1054,1057,83,1307,2525,1100,36,890,1103,1065,608,1175,204
0.1905477242530135,3.4199522827989974,3.293254641370149,0.2192953010576298,0.17611273471205496,1.3586851022140123,-0.5036894974780469,0.1905477242530135,-0.13692690238543065,-0.3089938532666943,0.78839669765801,3.380672156928985,-1.119394022350341,-0.8107713240707701,3.105839691433299,0.4846014092491796,0.5252609862464442,1.1714797320050525,-0.43794554085718024,-0.3409219722772057,1.4271945957883734,-0.15232845914399104,-0.587106244130671,-0.5703108638932032,0.04431638803769443,0.8900005618991303,-0.5703108638932032,-0.8816714825203786,-1.3299369864356707,0.38845375763582707,-0.37305474027032975,-0.00038868636313022414,-0.6378349653375106,-0.6890863348428883,1.8624446742934746,0.37456954772114676,1.6710149037139495,-0.7756984250375901,-0.7756984250375901,0.3186519434677123,0.04431638803769443,0.6056254989038173,-2.0224789299810415,-0.030413098045804464,1.851989450905129,-0.4053949717396913,1.9040605759318283,0.1471191126541989,0.26211431465637414,2.5475999117636636,-1.1006945383567346,0.7755544905767453,-0.7756984250375901,0.29046154644551864,-0.015378603154741318,0.6978221404482146,1.605631086088607,0.08863020155351369,0.17611273471205496,1.3240912296129024,-0.24574059272730153,-0.1677772467277911,0.029458532651360454,0.029458532651360454,2.3511047492659554,-0.13692690238543065,-1.0265997707300218,-0.00038868636313022414,2.946016924906694,0.17611273471205496,-0.00038868636313022414,0.029458532651360454,0.49819048944279026,-0.04549245437206825,1.5394252878937733
2,719
Negative regulation of ion transmembrane transport
6
14
2.313698
0.020684
O75915,P78417,P21796,Q9HD26,P62942,Q06787
Processes and pathways
GO Biological process
msigdb_gobp
383,162,12,308,187,409
2040,383,1036,12,1485,1604,640,187,162,409,695,474,308,1380
-0.5703108638932032,0.8774087768247075,0.04431638803769443,3.451175716066335,-0.23005094416154934,-0.3089938532666943,0.44361639063605623,1.605631086088607,1.7355981785016048,0.826732699034428,0.37456954772114676,0.6978221404482146,1.147599572470142,-0.1677772467277911
2,719
Monovalent inorganic cation homeostasis
10
22
2.312904
0.020728
P51790,P05023,Q9Y487,O75503,Q15904,Q8N511,Q93050,Q96PU5,P50897,P61421
Processes and pathways
GO Biological process
msigdb_gobp
261,295,395,231,240,48,401,474,24,348
231,1599,295,751,1653,1770,24,1297,261,1114,471,348,240,48,401,644,474,1178,973,395,2647,2608
1.404457491582026,-0.3089938532666943,1.1714797320050525,0.30457623372576403,-0.3409219722772057,-0.4053949717396913,3.1471316821409943,-0.13692690238543065,1.289267000376432,-0.015378603154741318,0.6978221404482146,0.9896472724402028,1.3701657615426401,2.763729779838205,0.8521328477933847,0.44361639063605623,0.6978221404482146,-0.04549245437206825,0.10331578012873843,0.8647862588625002,-1.4088026042446877,-1.213975141317416
2,719
Proton transmembrane transport
17
41
2.305569
0.021135
P24539,O75964,P36543,P51790,P05023,P05141,Q96ES6,Q9UDW1,Q7KZN9,P56385,P00403,P61421,P20674,P12235,Q00325,P13073,P47985
Processes and pathways
GO Biological process
msigdb_gobp
98,34,515,261,295,327,300,14,364,336,305,348,504,186,566,286,408
856,2040,726,872,804,34,305,295,327,751,1006,1291,186,286,504,877,2404,98,2476,1485,807,794,515,2182,408,2520,261,852,336,348,566,1304,364,300,2470,593,1151,14,1178,973,1087
0.1905477242530135,-0.5703108638932032,0.332688904231155,0.17611273471205496,0.2478813025768698,2.971565848245718,1.147599572470142,1.1714797320050525,1.0631453851685053,0.30457623372576403,0.07390195373379957,-0.13692690238543065,1.605631086088607,1.2189142308211247,0.632136528586786,0.17611273471205496,-0.8638509468356808,2.215993204297903,-0.9536034576855446,-0.23005094416154934,0.2478813025768698,0.26211431465637414,0.6188981125431084,-0.6548601180580003,0.826732699034428,-1.0265997707300218,1.289267000376432,0.20494183108481331,1.0265264066984594,0.9896472724402028,0.5387428051993683,-0.13692690238543065,0.9525040135933169,1.1595533384376537,-0.9355219790549657,0.5117436144293259,-0.030413098045804464,3.427774762153474,-0.04549245437206825,0.10331578012873843,0.014556932935040613
2,719
Mitochondrial carrier protein [IPR002067]
7
10
2.305484
0.021139
Q9UJS0,Q96H78,P05141,Q6NUK1,P12236,Q9BQT8,P12235
Sequence
InterPro Family
interpro_family
262,70,327,299,143,311,186
600,449,327,186,143,781,299,70,311,262
0.49819048944279026,0.736834876495512,1.0631453851685053,1.605631086088607,1.8832934520415403,0.2763076509973368,1.1595533384376537,2.5199648159717087,1.1356182999373312,1.289267000376432
2,719
Ion transmembrane transport
47
132
2.303597
0.021245
Q15043,O75915,Q9UJS0,P51790,P21796,Q9H2D1,Q9UDW1,P12236,Q9Y277,P45880,Q9UHG3,P13073,Q06787,P47985,O75964,P78417,Q9UBX3,P05023,P20020,Q96ES6,Q9Y4C2,Q9C0H2,P00403,Q9HD26,Q9BQT8,P12235,P62942,O43772,P08183,O75746,O95202,P05141,Q70HW3,Q8TB61,Q9H9B4,P56385,O75844,Q6P4A7,Q96PU5,P61421,O60831,P24539,P07384,Q7KZN9,Q9HD20,Q6P4Q7,Q9Y619
Processes and pathways
GO Biological process
msigdb_gobp
386,383,262,261,12,13,14,143,146,22,28,286,409,408,34,162,38,295,170,300,47,49,305,308,311,186,187,437,322,449,326,327,76,78,334,336,82,210,474,348,95,98,249,364,120,122,125
2067,856,2040,726,437,600,979,2041,95,727,2246,872,513,1265,449,82,383,804,34,326,305,295,327,1650,751,2071,249,2103,322,806,1006,1036,1291,1601,186,143,286,547,1627,170,504,877,2404,2575,12,98,2476,2075,1485,1604,807,2368,794,515,2182,1385,1459,22,878,408,2520,1185,261,781,823,1114,471,852,336,348,1715,640,187,162,566,1366,677,882,409,1391,2422,695,1304,1743,1202,759,883,386,2390,864,1780,210,122,76,364,2138,799,2395,989,78,2454,844,300,2235,646,474,2470,593,1230,311,1151,1256,49,13,1400,334,120,308,2671,38,14,1178,28,973,262,1087,146,1380,47,1316,125,2608
-0.587106244130671,0.1905477242530135,-0.5703108638932032,0.332688904231155,0.7626802321711698,0.49819048944279026,0.08863020155351369,-0.5703108638932032,2.22575796347679,0.332688904231155,-0.7062882632563935,0.17611273471205496,0.6188981125431084,-0.12157226993528147,0.736834876495512,2.3511047492659554,0.8774087768247075,0.2478813025768698,2.971565848245718,1.0631453851685053,1.147599572470142,1.1714797320050525,1.0631453851685053,-0.3409219722772057,0.30457623372576403,-0.587106244130671,1.3471792062317862,-0.6039584463179856,1.087415425314427,0.2478813025768698,0.07390195373379957,0.04431638803769443,-0.13692690238543065,-0.3089938532666943,1.605631086088607,1.8832934520415403,1.2189142308211247,0.5656005771908399,-0.32493250526949763,1.6710149037139495,0.632136528586786,0.17611273471205496,-0.8638509468356808,-1.138164966594554,3.451175716066335,2.215993204297903,-0.9536034576855446,-0.587106244130671,-0.23005094416154934,-0.3089938532666943,0.2478813025768698,-0.8284013522129561,0.26211431465637414,0.6188981125431084,-0.6548601180580003,-0.18327357472878134,-0.2144101059765268,3.253054371219224,0.17611273471205496,0.826732699034428,-1.0265997707300218,-0.0606169582349026,1.289267000376432,0.2763076509973368,0.23360837776605786,-0.015378603154741318,0.6978221404482146,0.20494183108481331,1.0265264066984594,0.9896472724402028,-0.37305474027032975,0.44361639063605623,1.605631086088607,1.7355981785016048,0.5387428051993683,-0.1677772467277911,0.402300331182603,0.17611273471205496,0.826732699034428,-0.18327357472878134,-0.8816714825203786,0.37456954772114676,-0.13692690238543065,-0.38919874485326694,-0.07578689853775272,0.30457623372576403,0.17611273471205496,0.8774087768247075,-0.8460943992105768,0.1905477242530135,-0.4053949717396913,1.494820444712504,1.98632596881489,2.436197942025277,0.9525040135933169,-0.620867881511793,0.26211431465637414,-0.8460943992105768,0.08863020155351369,2.379619278698563,-0.9175064966386184,0.2192953010576298,1.1595533384376537,-0.6890863348428883,0.44361639063605623,0.6978221404482146,-0.9355219790549657,0.5117436144293259,-0.09100256702323781,1.1356182999373312,-0.030413098045804464,-0.10626425831084813,2.763729779838205,3.4433864453496845,-0.18327357472878134,1.038761445699194,2.0066948267496136,1.147599572470142,-1.5704713475646683,2.911763976530236,3.427774762153474,-0.04549245437206825,3.0892351012046553,0.10331578012873843,1.289267000376432,0.014556932935040613,1.8832934520415403,-0.1677772467277911,2.7725504193892325,-0.13692690238543065,1.965878763574573,-1.213975141317416
2,719
Protein exit from endoplasmic reticulum
9
20
2.298379
0.02154
P51572,Q9UBV2,O15260,O15027,Q9HCU5,Q8TCT9,Q9BUN8,P49257,P14625
Processes and pathways
GO Biological process
msigdb_gobp
385,173,330,237,476,498,116,470,443
237,330,443,470,385,2228,1462,811,1809,867,498,1064,691,116,932,476,531,173,831,974
1.3816213018328303,1.0509677239800752,0.7497737515679389,0.6978221404482146,0.8774087768247075,-0.6890863348428883,-0.2144101059765268,0.2478813025768698,-0.421643782078971,0.1905477242530135,0.6453409341751739,0.029458532651360454,0.38845375763582707,2.087399401896311,0.13255997690276794,0.6978221404482146,0.6056254989038173,1.6710149037139495,0.23360837776605786,0.10331578012873843
2,719
Secondary alcohol metabolic process
12
40
2.291352
0.021943
Q06520,P04062,O75845,P16435,Q14739,Q8WTV0,O76054,Q15392,Q14849,Q15800,Q16850,Q9BQE5
Processes and pathways
GO Biological process
msigdb_gobp
5,71,203,238,207,110,148,52,87,23,154,29
273,1708,203,1215,148,1762,1625,71,1601,1092,238,1933,1020,2597,2501,1359,796,2209,2462,2227,2302,446,2323,2631,5,2577,207,87,1555,2436,52,2643,23,154,885,110,2578,29,1672,2473
1.2542091223510612,-0.37305474027032975,1.5394252878937733,-0.09100256702323781,1.8624446742934746,-0.4053949717396913,-0.32493250526949763,2.5107215183813394,-0.3089938532666943,-0.00038868636313022414,1.3816213018328303,-0.5036894974780469,0.05913077172037472,-1.213975141317416,-0.9899664782882975,-0.1677772467277911,0.26211431465637414,-0.6719437646434965,-0.9355219790549657,-0.6890863348428883,-0.7582546181179882,0.7497737515679389,-0.7756984250375901,-1.31041805381167,3.7466882849921066,-1.138164966594554,1.5060072044287904,2.3128479941750375,-0.2772676267666931,-0.8995564994467704,2.74604529197796,-1.3495342310278062,3.2287919262177374,1.7888209300317397,0.17611273471205496,2.1471356130946906,-1.138164966594554,3.055873620168304,-0.3409219722772057,-0.9355219790549657
2,719
Disproportionate short limb short stature
7
15
2.283694
0.02239
O75718,Q32P28,O00116,Q14739,Q15392,Q6DKJ4,P10644
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
294,360,218,207,52,123,31
218,2557,294,31,2299,913,1631,1880,207,52,360,123,496,382,1672
1.4611164567099202,-1.1006945383567346,1.1714797320050525,3.0391160654016716,-0.7582546181179882,0.1471191126541989,-0.32493250526949763,-0.47070938318962924,1.5060072044287904,2.74604529197796,0.9649146958521644,1.965878763574573,0.6453409341751739,0.8900005618991303,-0.3409219722772057
2,719
ER-Golgi transport
14
45
2.279413
0.022643
Q9Y282,P51572,Q969X5,Q15363,Q12981,P24390,O95197,Q7Z392,O15027,Q6NUQ1,Q9HCU5,Q9P2W9,P49257,P49755
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
2,385,392,69,228,9,43,398,237,145,476,20,470,495
1263,237,1622,1546,1051,1004,2248,43,1132,1323,1548,9,900,1631,470,495,385,2386,2212,2185,1778,2186,771,1271,228,1611,69,1056,2553,2482,145,398,841,2340,969,392,1443,476,531,20,2036,2,1982,1157,974
-0.12157226993528147,1.3816213018328303,-0.32493250526949763,-0.2772676267666931,0.029458532651360454,0.07390195373379957,-0.7062882632563935,2.798926517414969,-0.030413098045804464,-0.15232845914399104,-0.2772676267666931,3.672408462929854,0.16163661432793977,-0.32493250526949763,0.6978221404482146,0.6453409341751739,0.8774087768247075,-0.8460943992105768,-0.6719437646434965,-0.6548601180580003,-0.4053949717396913,-0.6548601180580003,0.29046154644551864,-0.12157226993528147,1.4271945957883734,-0.3089938532666943,2.5199648159717087,0.029458532651360454,-1.082065937615682,-0.9536034576855446,1.8832934520415403,0.8521328477933847,0.2192953010576298,-0.7932038385838693,0.10331578012873843,0.8647862588625002,-0.19881775585569805,0.6978221404482146,0.6056254989038173,3.317234140715181,-0.5535718990503548,4.013195205240466,-0.5202616114390414,-0.030413098045804464,0.10331578012873843
2,719
Rac2 gtpase cycle
11
28
2.276854
0.022795
P02786,Q7L576,P42166,Q13505,O15173,P42167,Q14739,Q13177,P49257,P50402,Q86XL3
Processes and pathways
Reactome Pathways
msigdb_reactome
450,391,390,105,107,346,207,178,470,403,58
107,981,450,1650,390,346,1853,470,403,1297,1163,1633,1858,178,105,1430,207,1973,915,391,58,2063,594,2485,1126,871,737,502
2.1767547750820517,0.08863020155351369,0.736834876495512,-0.3409219722772057,0.8647862588625002,1.0019694664850602,-0.4543006169521521,0.6978221404482146,0.8394483821163174,-0.13692690238543065,-0.04549245437206825,-0.32493250526949763,-0.4543006169521521,1.6275159466122078,2.1865914316960353,-0.19881775585569805,1.5060072044287904,-0.5202616114390414,0.1471191126541989,0.8647862588625002,2.611536121609732,-0.5703108638932032,0.5117436144293259,-0.9536034576855446,-0.015378603154741318,0.1905477242530135,0.332688904231155,0.6453409341751739
2,719
Abnormality of extrapyramidal motor function
19
66
2.270686
0.023166
Q15043,P17900,Q9NZJ7,P35637,Q06787,Q96JX3,Q9H0B6,Q99720,P07602,Q9H078,P06865,O75792,P12235,P35270,P04062,O14949,P16278,Q9H6K4,Q6DKK2
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
386,135,265,276,409,289,290,36,168,172,177,182,186,319,71,72,206,225,118
72,563,1108,872,182,609,1847,71,1734,177,168,1818,1600,683,186,206,2558,135,1196,2250,2532,807,1161,319,276,1459,1739,2130,484,2228,1904,861,2215,579,1510,1635,2409,409,2331,1223,568,386,1804,2356,118,1334,441,289,2165,2470,36,1230,1151,172,290,225,869,1671,265,736,870,1520,1049,1451,803,1316
2.4828960163826035,0.5387428051993683,-0.015378603154741318,0.17611273471205496,1.6165848812880583,0.4846014092491796,-0.4543006169521521,2.5107215183813394,-0.38919874485326694,1.6275159466122078,1.69263057727874,-0.43794554085718024,-0.3089938532666943,0.38845375763582707,1.605631086088607,1.5060072044287904,-1.1006945383567346,1.9247467241533158,-0.07578689853775272,-0.7062882632563935,-1.0450191132829518,0.2478813025768698,-0.04549245437206825,1.0995080860970046,1.2424706616319041,-0.2144101059765268,-0.38919874485326694,-0.620867881511793,0.671648454750572,-0.6890863348428883,-0.48717221640031005,0.1905477242530135,-0.6719437646434965,0.5252609862464442,-0.24574059272730153,-0.32493250526949763,-0.8638509468356808,0.826732699034428,-0.7932038385838693,-0.09100256702323781,0.5387428051993683,0.8774087768247075,-0.421643782078971,-0.8107713240707701,2.04720003960902,-0.15232845914399104,0.7626802321711698,1.195250933615223,-0.6378349653375106,-0.9355219790549657,2.946016924906694,-0.09100256702323781,-0.030413098045804464,1.6710149037139495,1.195250933615223,1.4385262761005175,0.1905477242530135,-0.3409219722772057,1.2776071666564428,0.332688904231155,0.1905477242530135,-0.24574059272730153,0.04431638803769443,-0.19881775585569805,0.26211431465637414,-0.13692690238543065
2,719
Metapathway biotransformation phase i and ii
6
20
2.263143
0.023627
P78417,Q06520,P21964,O15217,Q8NCH0,Q16850
Processes and pathways
WikiPathways
msigdb_wp
162,5,171,51,56,154
978,51,2567,192,2648,2151,2612,171,1020,2153,2129,162,5,154,1079,56,420,891,1753,2066
0.08863020155351369,2.74604529197796,-1.119394022350341,1.5836549017230799,-1.428719909350296,-0.6378349653375106,-1.233112298811929,1.6710149037139495,0.05913077172037472,-0.6378349653375106,-0.620867881511793,1.7355981785016048,3.7466882849921066,1.7888209300317397,0.014556932935040613,2.6657421041309006,0.8139856344410125,0.17611273471205496,-0.38919874485326694,-0.5703108638932032
2,719
L amino acid transport
6
10
2.261894
0.023704
O60831,O75915,Q9UJS0,Q9H9B4,Q96QD8,Q9Y619
Processes and pathways
GO Biological process
msigdb_gobp
95,383,262,334,147,125
95,449,383,1650,806,864,147,334,262,125
2.22575796347679,0.736834876495512,0.8774087768247075,-0.3409219722772057,0.2478813025768698,0.1905477242530135,1.8728793126258834,1.038761445699194,1.289267000376432,1.965878763574573
2,719
Sterol metabolic process
12
37
2.258157
0.023936
Q06520,P04062,O75845,P16435,Q14739,Q8WTV0,O76054,Q15392,Q14849,Q15800,Q16850,Q9BQE5
Processes and pathways
GO Biological process
msigdb_gobp
5,71,203,238,207,110,148,52,87,23,154,29
273,203,148,1762,1625,71,1601,1092,238,1933,1020,2597,2636,2501,1359,2209,2227,2302,446,2323,2631,5,2577,207,87,1555,2436,52,2643,23,154,885,110,29,1672,2473,345
1.2542091223510612,1.5394252878937733,1.8624446742934746,-0.4053949717396913,-0.32493250526949763,2.5107215183813394,-0.3089938532666943,-0.00038868636313022414,1.3816213018328303,-0.5036894974780469,0.05913077172037472,-1.213975141317416,-1.3299369864356707,-0.9899664782882975,-0.1677772467277911,-0.6719437646434965,-0.6890863348428883,-0.7582546181179882,0.7497737515679389,-0.7756984250375901,-1.31041805381167,3.7466882849921066,-1.138164966594554,1.5060072044287904,2.3128479941750375,-0.2772676267666931,-0.8995564994467704,2.74604529197796,-1.3495342310278062,3.2287919262177374,1.7888209300317397,0.17611273471205496,2.1471356130946906,3.055873620168304,-0.3409219722772057,-0.9355219790549657,1.014262462244214
2,719
Cardiac muscle contraction
8
19
2.253041
0.024257
P05023,O14949,P14406,Q9UDW1,P00403,P20674,P13073,P47985
Processes and pathways
KEGG Pathways
msigdb_kegg
295,72,73,14,305,504,286,408
72,305,295,1734,1006,1819,1796,1291,286,73,2317,1602,547,504,638,807,408,1114,14
2.4828960163826035,1.147599572470142,1.1714797320050525,-0.38919874485326694,0.07390195373379957,-0.43794554085718024,-0.421643782078971,-0.13692690238543065,1.2189142308211247,2.4828960163826035,-0.7756984250375901,-0.3089938532666943,0.5656005771908399,0.632136528586786,0.44361639063605623,0.2478813025768698,0.826732699034428,-0.015378603154741318,3.427774762153474
2,719
Amino acid transmembrane transport
6
11
2.25056
0.024413
O60831,O75915,Q9UJS0,Q9H9B4,Q96QD8,Q9Y619
Processes and pathways
GO Biological process
msigdb_gobp
95,383,262,334,147,125
95,449,383,1650,806,864,646,147,334,262,125
2.22575796347679,0.736834876495512,0.8774087768247075,-0.3409219722772057,0.2478813025768698,0.1905477242530135,0.44361639063605623,1.8728793126258834,1.038761445699194,1.289267000376432,1.965878763574573
2,719
Delusions
7
14
2.248447
0.024548
Q9UJS0,P04062,P07602,Q9NZJ7,O43681,P21964,Q9BQE5
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
262,71,168,265,389,171,29
389,71,168,2458,171,1549,1459,505,1554,2001,29,1789,265,262
0.8647862588625002,2.5107215183813394,1.69263057727874,-0.9355219790549657,1.6710149037139495,-0.2772676267666931,-0.2144101059765268,0.632136528586786,-0.2772676267666931,-0.5368889474821656,3.055873620168304,-0.4053949717396913,1.2776071666564428,1.289267000376432
2,719
Lipid localization
22
66
2.245439
0.02474
P17900,Q9NZJ7,O15118,Q9BZF1,Q9BQE5,Q96JX3,Q99720,P09455,P07602,Q9BUR5,O43772,P35790,P61916,Q14108,P08183,P04062,O15260,Q16739,Q14849,P10909,Q8WTV0,Q9H6V9
Processes and pathways
GO Biological process
msigdb_gobp
135,265,273,281,29,289,36,422,168,179,437,60,446,193,322,71,330,83,87,466,110,129
908,2707,273,330,437,600,1033,857,1132,1182,601,2489,1894,71,2122,2071,168,1818,2273,322,422,466,1355,135,2251,1137,478,740,1111,60,753,629,446,2323,2132,1717,1466,193,87,83,915,885,2337,746,632,2689,110,2645,289,1396,36,29,2063,179,1343,281,2239,129,265,1404,2473,1087,667,830,831,974
0.1471191126541989,-3.0796995145193136,1.2542091223510612,1.0509677239800752,0.7626802321711698,0.49819048944279026,0.04431638803769443,0.1905477242530135,-0.030413098045804464,-0.0606169582349026,0.49819048944279026,-0.9717514496482177,-0.48717221640031005,2.5107215183813394,-0.620867881511793,-0.587106244130671,1.69263057727874,-0.43794554085718024,-0.7235499894095512,1.087415425314427,0.8012070229052979,0.6978221404482146,-0.1677772467277911,1.9247467241533158,-0.7062882632563935,-0.030413098045804464,0.6847519362737263,0.3186519434677123,-0.015378603154741318,2.6024486449078035,0.30457623372576403,0.457314566306333,0.7497737515679389,-0.7756984250375901,-0.620867881511793,-0.37305474027032975,-0.2144101059765268,1.5836549017230799,2.3128479941750375,2.3511047492659554,0.1471191126541989,0.17611273471205496,-0.7932038385838693,0.3186519434677123,0.457314566306333,-1.8670529333472237,2.1471356130946906,-1.3495342310278062,1.195250933615223,-0.18327357472878134,2.946016924906694,3.055873620168304,-0.5703108638932032,1.6275159466122078,-0.15232845914399104,1.2424706616319041,-0.6890863348428883,1.945352566311608,1.2776071666564428,-0.18327357472878134,-0.9355219790549657,0.014556932935040613,0.41610948501277006,0.23360837776605786,0.23360837776605786,0.10331578012873843
2,719
Regulation of amyloid precursor protein catabolic process
6
14
2.241302
0.025007
O95197,Q9NQC3,O75298,P49840,P62942,P10909
Processes and pathways
GO Biological process
msigdb_gobp
43,109,303,432,187,466
832,303,43,466,2075,495,432,187,1906,1526,1203,1280,1562,109
0.2192953010576298,1.147599572470142,2.798926517414969,0.6978221404482146,-0.587106244130671,0.6453409341751739,0.7755544905767453,1.605631086088607,-0.48717221640031005,-0.2614793772811411,-0.07578689853775272,-0.12157226993528147,-0.2772676267666931,2.157026937488641
2,719
Elevated pulmonary artery pressure
9
19
2.23402
0.025482
Q14108,P04062,O96000,Q6NUK1,P00403,Q8IZA0,O75844,Q71SY5,P03886
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
193,71,426,299,305,338,82,57,26
2487,82,426,305,1354,26,71,1321,504,2575,2476,686,769,193,299,57,338,644,1085
-0.9717514496482177,2.3511047492659554,0.78839669765801,1.147599572470142,-0.1677772467277911,3.105839691433299,2.5107215183813394,-0.15232845914399104,0.632136528586786,-1.138164966594554,-0.9536034576855446,0.38845375763582707,0.29046154644551864,1.5836549017230799,1.1595533384376537,2.6206083231740736,1.0265264066984594,0.44361639063605623,0.014556932935040613
2,719
Vacuole organization
20
43
2.233034
0.025547
Q96AX1,Q9Y371,O14773,P54802,Q8NHS3,Q9UN37,Q9BV81,P11117,P50897,P16615,Q8N511,Q8TBX8,Q14108,P04062,Q9H269,O75503,Q9H0U4,P53365,Q86Y82,P10253
Processes and pathways
GO Biological process
msigdb_gobp
644,520,134,264,270,667,541,275,24,547,48,572,193,71,624,231,366,614,632,380
2147,134,1004,231,941,71,2071,1818,380,275,547,1684,913,673,24,1297,614,264,1826,1364,771,927,193,1392,915,746,632,48,270,572,2340,644,2265,2165,541,366,624,1122,2144,1048,667,1865,520
-0.6378349653375106,1.9247467241533158,0.07390195373379957,1.404457491582026,0.11795895191442474,2.5107215183813394,-0.587106244130671,-0.43794554085718024,0.8900005618991303,1.2424706616319041,0.5656005771908399,-0.3569626006240997,0.1471191126541989,0.402300331182603,3.1471316821409943,-0.13692690238543065,0.4846014092491796,1.2776071666564428,-0.43794554085718024,-0.1677772467277911,0.29046154644551864,0.13255997690276794,1.5836549017230799,-0.18327357472878134,0.1471191126541989,0.3186519434677123,0.457314566306333,2.763729779838205,1.2659212488513751,0.5387428051993683,-0.7932038385838693,0.44361639063605623,-0.7062882632563935,-0.6378349653375106,0.5923184989479339,0.9525040135933169,0.4846014092491796,-0.015378603154741318,-0.620867881511793,0.04431638803769443,0.41610948501277006,-0.4543006169521521,0.6188981125431084
2,719
Protein import
26
78
2.231709
0.025634
Q8NFH5,Q8TEX9,Q99595,Q9NS69,O15397,Q7Z4Q2,O60830,O00410,Q8N1F7,O75381,O75694,O14925,O60518,P40855,O00505,O60684,P57740,O95831,Q15388,Q92973,P52294,Q14974,P10909,O14737,Q13043,O43615
Processes and pathways
GO Biological process
msigdb_gobp
132,133,6,11,266,405,19,402,287,417,161,54,438,317,325,455,472,465,219,90,220,349,466,368,372,379
402,325,368,2474,54,266,379,438,455,19,1962,417,161,628,779,465,609,1354,1795,1072,1133,1239,2430,466,1240,1765,1822,2575,2076,1504,2126,1487,317,2078,1937,1606,220,1200,835,472,551,1188,1218,372,1223,1945,349,2658,219,1250,732,714,2569,1010,817,405,287,132,133,2116,90,1280,2091,1563,6,593,2623,2310,1401,971,11,1568,1178,937,1088,1048,502,546
0.8394483821163174,1.0631453851685053,0.9400635335930252,-0.9536034576855446,2.6657421041309006,1.2659212488513751,0.8900005618991303,0.7626802321711698,0.723863433268658,3.317234140715181,-0.5202616114390414,0.8139856344410125,1.7355981785016048,0.457314566306333,0.2763076509973368,0.6978221404482146,0.4846014092491796,-0.1677772467277911,-0.421643782078971,0.014556932935040613,-0.030413098045804464,-0.10626425831084813,-0.8995564994467704,0.6978221404482146,-0.10626425831084813,-0.4053949717396913,-0.43794554085718024,-1.138164966594554,-0.587106244130671,-0.24574059272730153,-0.620867881511793,-0.23005094416154934,1.111572693459288,-0.587106244130671,-0.5036894974780469,-0.3089938532666943,1.4498335257671533,-0.07578689853775272,0.2192953010576298,0.6978221404482146,0.5656005771908399,-0.0606169582349026,-0.09100256702323781,0.9275931030431922,-0.09100256702323781,-0.5036894974780469,0.9896472724402028,-1.4688005294598216,1.4611164567099202,-0.10626425831084813,0.332688904231155,0.34668734253092304,-1.119394022350341,0.07390195373379957,0.2478813025768698,0.8394483821163174,1.2189142308211247,1.9350596419712964,1.9350596419712964,-0.6039584463179856,2.2646396892872667,-0.12157226993528147,-0.587106244130671,-0.2772676267666931,3.7466882849921066,0.5117436144293259,-1.2716124786728344,-0.7582546181179882,-0.18327357472878134,0.10331578012873843,3.474477642713755,-0.2772676267666931,-0.04549245437206825,0.13255997690276794,0.014556932935040613,0.04431638803769443,0.6453409341751739,0.5789769223558233
2,719
Negative regulation of ion transport
6
16
2.225891
0.026021
O75915,P78417,P21796,Q9HD26,P62942,Q06787
Processes and pathways
GO Biological process
msigdb_gobp
383,162,12,308,187,409
2040,383,1036,12,1485,1604,640,187,162,409,695,474,1400,308,1569,1380
-0.5703108638932032,0.8774087768247075,0.04431638803769443,3.451175716066335,-0.23005094416154934,-0.3089938532666943,0.44361639063605623,1.605631086088607,1.7355981785016048,0.826732699034428,0.37456954772114676,0.6978221404482146,-0.18327357472878134,1.147599572470142,-0.2772676267666931,-0.1677772467277911
2,719
Nuclear import signal receptor activity
8
12
2.224468
0.026117
O00505,Q8TEX9,O60684,O00410,O60518,Q92973,P52294,Q14974
Functions
GO Molecular function
msigdb_gomf
325,133,455,402,438,90,220,349
402,325,2474,438,455,1606,220,349,133,90,1280,546
0.8394483821163174,1.0631453851685053,-0.9536034576855446,0.7626802321711698,0.723863433268658,-0.3089938532666943,1.4498335257671533,0.9896472724402028,1.9350596419712964,2.2646396892872667,-0.12157226993528147,0.5789769223558233
2,719
Protein localization to endoplasmic reticulum
12
32
2.222881
0.026224
Q15629,Q96HY6,P51572,P24390,Q9NQC3,O15027,Q9UGP8,O15258,Q9Y5M8,O43292,Q15005,P46379
Processes and pathways
GO Biological process
msigdb_gobp
96,356,385,9,109,237,79,371,119,248,283,191
237,371,248,389,1002,2428,1989,1768,9,1574,191,539,385,1462,1826,1551,2156,492,1715,283,96,2482,2699,1279,356,1282,1122,109,1404,79,648,119
1.3816213018328303,0.9275931030431922,1.3471792062317862,0.8647862588625002,0.07390195373379957,-0.8995564994467704,-0.5368889474821656,-0.4053949717396913,3.672408462929854,-0.2931056735100328,1.594654460100512,0.5923184989479339,0.8774087768247075,-0.2144101059765268,-0.43794554085718024,-0.2772676267666931,-0.6378349653375106,0.6585115148857332,-0.37305474027032975,1.2307057402478268,2.22575796347679,-0.9536034576855446,-2.2773891393535837,-0.12157226993528147,0.9772957319876318,-0.12157226993528147,-0.015378603154741318,2.157026937488641,-0.18327357472878134,2.379619278698563,0.44361639063605623,2.037102603070871
2,719
Passive transmembrane transporter activity
8
29
2.222734
0.026234
P24539,O75964,P51790,Q99797,P21796,Q9C0H2,Q9Y277,P45880
Functions
GO Molecular function
msigdb_gomf
98,34,261,201,12,49,146,22
2067,804,34,609,751,2071,2103,12,98,2476,794,2182,22,2520,261,852,336,1715,1366,1391,989,2454,844,709,201,1256,49,146,2608
-0.587106244130671,0.2478813025768698,2.971565848245718,0.4846014092491796,0.30457623372576403,-0.587106244130671,-0.6039584463179856,3.451175716066335,2.215993204297903,-0.9536034576855446,0.26211431465637414,-0.6548601180580003,3.253054371219224,-1.0265997707300218,1.289267000376432,0.20494183108481331,1.0265264066984594,-0.37305474027032975,-0.1677772467277911,-0.18327357472878134,0.08863020155351369,-0.9175064966386184,0.2192953010576298,0.3606474828614861,1.5615865779228295,-0.10626425831084813,2.763729779838205,1.8832934520415403,-1.213975141317416
2,719
Oxidoreduction driven active transmembrane transporter activity
9
26
2.221515
0.026316
Q9P0J0,Q9UDW1,O43676,Q7KZN9,P00403,O75306,P03886,P13073,P47985
Functions
GO Molecular function
msigdb_gomf
204,14,15,364,305,244,26,286,408
856,15,872,244,1924,858,1289,1598,426,305,26,1006,1291,286,2225,504,2693,807,408,2559,769,1057,1307,364,204,14
0.1905477242530135,3.4199522827989974,0.17611273471205496,1.3586851022140123,-0.5036894974780469,0.1905477242530135,-0.13692690238543065,-0.3089938532666943,0.78839669765801,1.147599572470142,3.105839691433299,0.07390195373379957,-0.13692690238543065,1.2189142308211247,-0.6890863348428883,0.632136528586786,-2.0224789299810415,0.2478813025768698,0.826732699034428,-1.1006945383567346,0.29046154644551864,0.029458532651360454,-0.13692690238543065,0.9525040135933169,1.5394252878937733,3.427774762153474
2,719
Negative regulation of transmembrane transport
7
17
2.211956
0.02697
O75915,P78417,P21796,P49840,Q9HD26,P62942,Q06787
Processes and pathways
GO Biological process
msigdb_gobp
383,162,12,432,308,187,409
1452,2040,383,1036,12,1485,1604,432,640,187,162,2132,409,695,474,308,1380
-0.2144101059765268,-0.5703108638932032,0.8774087768247075,0.04431638803769443,3.451175716066335,-0.23005094416154934,-0.3089938532666943,0.7755544905767453,0.44361639063605623,1.605631086088607,1.7355981785016048,-0.620867881511793,0.826732699034428,0.37456954772114676,0.6978221404482146,1.147599572470142,-0.1677772467277911
2,719