term
stringlengths 2
121
| overlap
int64 6
281
| setsize
int64 7
499
| score
float64 1.96
10.6
| pval
float64 0
0.05
| edge
stringlengths 41
1.97k
| type
stringclasses 5
values | subtype
stringclasses 24
values | subtype_key
stringclasses 24
values | edge_idxs
stringlengths 11
1.17k
| ann_idxs
stringlengths 19
2.31k
| ann_vals
stringlengths 124
9.94k
| sig_size
int64 2.2k
3.73k
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Protease
| 52
| 116
| 3.962764
| 0.000074
|
P42785,Q9H3G5,Q5JRX3,Q14694,Q01804,P55210,Q92945,Q15365,Q96I24,P17655,Q96FW1,Q86TI2,P55786,Q9BYT8,P07858,O43847,Q9Y4P1,Q9NVG8,Q9BXI6,P13798,Q9HB40,P54578,P22695,Q9NZ08,P49915,P12268,Q6GQQ9,P17812,O60343,Q5TDH0,Q13510,Q06210,Q7L266,P31930,P55212,Q99497,Q16555,Q96RU2,Q9Y5K5,Q92820,P20839,O15484,P42575,Q9NY33,O75844,Q7L5N1,Q4KMP7,Q15366,P10619,P48147,Q9NRF8,O14773
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
4,5,131,613,372,604,558,377,443,258,441,697,26,570,154,152,310,184,182,530,47,174,533,51,415,670,199,672,661,429,685,684,621,676,82,790,617,218,359,785,335,329,96,644,101,777,242,239,592,475,395,117
|
1044,1136,2479,963,117,1354,329,152,661,1255,101,1364,1366,1741,1492,154,2197,592,670,3049,530,1375,258,672,335,1163,533,1984,2410,1069,676,2841,2987,2210,96,4,835,475,415,2732,749,2322,2588,839,2589,174,604,82,26,3053,2597,2007,372,1183,684,1524,1407,685,2744,1292,1297,613,377,239,617,242,2616,131,429,1192,199,621,777,697,3038,2143,2257,3079,1683,1006,1203,1914,1434,785,1209,2450,558,1012,935,441,443,1924,1109,218,1327,790,2045,1693,182,570,5,2161,47,395,184,644,51,1937,2912,1470,1832,811,310,2176,359,2874
|
0.2756939090187885,0.21278718307129618,-0.5817669225092277,0.3381272349672459,1.550946556196765,0.08552503374798644,0.9378771015302817,1.3882100669604411,0.5832629155020134,0.1493999725419618,1.657680089871788,0.08552503374798644,0.08552503374798644,-0.10910107725747438,0.021154959123965873,1.3882100669604411,-0.37590010541019514,0.6434302553162722,0.5832629155020134,-1.3833236694797724,0.7031636084840797,0.08552503374798644,1.1096416031090883,0.5832629155020134,0.9378771015302817,0.21278718307129618,0.7031636084840797,-0.24143086817602652,-0.5125776294717194,0.2756939090187885,0.5832629155020134,-0.9365999560555965,-1.2317465192005141,-0.37590010541019514,1.7105328972774696,6.273729161291968,0.4616012571920667,0.7624690661744893,0.8213525930752211,-0.7928498829766004,0.5226553678023891,-0.4439584005973705,-0.6515356333511229,0.4616012571920667,-0.6515356333511229,1.3332432815151989,0.6434302553162722,1.815231903298355,3.111810995117898,-1.3833236694797724,-0.6515356333511229,-0.24143086817602652,0.8798200308586908,0.21278718307129618,0.5832629155020134,0.021154959123965873,0.08552503374798644,0.5832629155020134,-0.7928498829766004,0.1493999725419618,0.1493999725419618,0.6434302553162722,0.8798200308586908,1.1661121430364376,0.6434302553162722,1.1661121430364376,-0.6515356333511229,1.4970570622608441,0.8213525930752211,0.21278718307129618,1.277907963516101,0.6434302553162722,0.5226553678023891,0.5832629155020134,-1.307191595712573,-0.30839382957997863,-0.37590010541019514,-1.460155105498623,-0.04371782774137989,0.3381272349672459,0.21278718307129618,-0.17500271918170665,0.08552503374798644,0.5226553678023891,0.21278718307129618,-0.5125776294717194,0.7031636084840797,0.3381272349672459,0.40009409100938204,0.8213525930752211,0.8213525930752211,-0.17500271918170665,0.2756939090187885,1.222199240405792,0.1493999725419618,0.5226553678023891,-0.24143086817602652,-0.04371782774137989,1.3332432815151989,0.7031636084840797,5.809318295160335,-0.30839382957997863,2.4168980616095,0.8798200308586908,1.3332432815151989,0.6434302553162722,2.3196296243830314,-0.17500271918170665,-1.009414400019985,0.08552503374798644,-0.10910107725747438,0.5226553678023891,1.0527824505275314,-0.30839382957997863,0.9378771015302817,-0.9365999560555965
| 3,216
|
Protease
| 34
| 85
| 3.880528
| 0.000104
|
P42785,Q9H3G5,Q5JRX3,Q14694,Q01804,P55210,P17655,Q96FW1,P55786,Q9BYT8,P07858,O43847,Q9Y4P1,Q9HB40,P54578,Q9NZ08,Q6GQQ9,Q4J6C6,Q5TDH0,P28072,Q7L266,P55212,Q96RU2,Q9Y5K5,O15484,Q9NUQ7,P42575,Q9NY33,O75844,Q86UV5,P48147,P10619,P09960,O14773
|
Functions
|
Protein Atlas Molecular function
|
protein_atlas_molecular_function
|
4,5,131,613,372,604,258,441,26,570,154,152,310,47,174,51,199,61,429,193,621,82,218,359,329,513,96,644,101,384,475,592,591,117
|
1044,2479,117,329,152,1255,101,1609,1364,1366,1492,154,591,592,3049,1375,258,193,898,2410,1069,2841,2987,2210,96,4,835,475,1511,749,2322,2588,839,174,604,82,26,3053,2735,372,2744,1297,613,1090,2349,61,131,429,199,621,697,384,3079,1203,1434,1209,2266,1012,1015,441,1440,1924,1109,218,1327,1813,790,2045,570,5,1223,2161,949,47,1706,1230,513,644,51,2912,1832,1833,310,2176,359
|
0.2756939090187885,-0.5817669225092277,1.550946556196765,0.9378771015302817,1.3882100669604411,0.1493999725419618,1.657680089871788,-0.04371782774137989,0.08552503374798644,0.08552503374798644,0.021154959123965873,1.3882100669604411,0.6434302553162722,0.6434302553162722,-1.3833236694797724,0.08552503374798644,1.1096416031090883,1.277907963516101,0.40009409100938204,-0.5125776294717194,0.2756939090187885,-0.9365999560555965,-1.2317465192005141,-0.37590010541019514,1.7105328972774696,6.273729161291968,0.4616012571920667,0.7624690661744893,0.021154959123965873,0.5226553678023891,-0.4439584005973705,-0.6515356333511229,0.4616012571920667,1.3332432815151989,0.6434302553162722,1.815231903298355,3.111810995117898,-1.3833236694797724,-0.7928498829766004,0.8798200308586908,-0.7928498829766004,0.1493999725419618,0.6434302553162722,0.2756939090187885,-0.4439584005973705,2.1715325399779393,1.4970570622608441,0.8213525930752211,1.277907963516101,0.6434302553162722,0.5832629155020134,0.8798200308586908,-1.460155105498623,0.21278718307129618,0.08552503374798644,0.21278718307129618,-0.37590010541019514,0.3381272349672459,0.3381272349672459,0.8213525930752211,0.08552503374798644,-0.17500271918170665,0.2756939090187885,1.222199240405792,0.1493999725419618,-0.10910107725747438,0.5226553678023891,-0.24143086817602652,0.7031636084840797,5.809318295160335,0.21278718307129618,-0.30839382957997863,0.40009409100938204,2.4168980616095,-0.04371782774137989,0.21278718307129618,0.7624690661744893,0.6434302553162722,2.3196296243830314,-1.009414400019985,-0.10910107725747438,-0.10910107725747438,1.0527824505275314,-0.30839382957997863,0.9378771015302817
| 3,216
|
Exopeptidase activity
| 7
| 32
| 3.731762
| 0.00019
|
P42785,Q9H3G5,Q969V3,O75844,Q9HB40,Q9NZ08,P55786
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
4,5,6,101,47,51,26
|
117,101,1609,1741,591,592,3049,2410,1069,1170,4,1511,2588,839,26,757,913,2744,697,2143,785,6,936,1109,791,5,1223,47,1706,1230,644,51
|
1.550946556196765,1.657680089871788,-0.04371782774137989,-0.10910107725747438,0.6434302553162722,0.6434302553162722,-1.3833236694797724,-0.5125776294717194,0.2756939090187885,0.21278718307129618,6.273729161291968,0.021154959123965873,-0.6515356333511229,0.4616012571920667,3.111810995117898,0.5226553678023891,0.40009409100938204,-0.7928498829766004,0.5832629155020134,-0.30839382957997863,0.5226553678023891,5.075890701055905,0.40009409100938204,0.2756939090187885,0.5226553678023891,5.809318295160335,0.21278718307129618,2.4168980616095,-0.04371782774137989,0.21278718307129618,0.6434302553162722,2.3196296243830314
| 3,216
|
Endopeptidase activity
| 27
| 61
| 3.448688
| 0.000563
|
Q5JRX3,Q14694,P17655,P28070,Q9BYT8,P07858,O43847,Q9Y4P1,P13798,P54578,P22695,Q9NZ08,Q4J6C6,P49720,P60900,P49721,Q5TDH0,P28072,P55212,Q96RU2,O15484,P42575,O75844,Q86UV5,P48147,P25789,O14773
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
131,613,258,136,570,154,152,310,530,174,533,51,61,414,539,64,429,193,82,218,329,96,101,384,475,595,117
|
117,329,152,1255,101,1364,1742,1492,154,530,1375,258,1496,533,595,136,193,898,1069,2311,2841,2987,2210,96,835,475,414,64,749,839,174,604,82,539,1524,2744,1297,613,2349,61,131,429,384,3079,1203,1434,1209,2266,1012,1924,218,1327,1813,2045,791,570,51,2912,1833,310,2176
|
1.550946556196765,0.9378771015302817,1.3882100669604411,0.1493999725419618,1.657680089871788,0.08552503374798644,-0.10910107725747438,0.021154959123965873,1.3882100669604411,0.7031636084840797,0.08552503374798644,1.1096416031090883,0.021154959123965873,0.7031636084840797,0.6434302553162722,1.4428130982976093,1.277907963516101,0.40009409100938204,0.2756939090187885,-0.4439584005973705,-0.9365999560555965,-1.2317465192005141,-0.37590010541019514,1.7105328972774696,0.4616012571920667,0.7624690661744893,0.8213525930752211,2.020717946656322,0.5226553678023891,0.4616012571920667,1.3332432815151989,0.6434302553162722,1.815231903298355,0.7031636084840797,0.021154959123965873,-0.7928498829766004,0.1493999725419618,0.6434302553162722,-0.4439584005973705,2.1715325399779393,1.4970570622608441,0.8213525930752211,0.8798200308586908,-1.460155105498623,0.21278718307129618,0.08552503374798644,0.21278718307129618,-0.37590010541019514,0.3381272349672459,-0.17500271918170665,1.222199240405792,0.1493999725419618,-0.10910107725747438,-0.24143086817602652,0.5226553678023891,0.7031636084840797,2.3196296243830314,-1.009414400019985,-0.10910107725747438,1.0527824505275314,-0.30839382957997863
| 3,216
|
Golgi membrane
| 31
| 112
| 3.374392
| 0.00074
|
Q13464,P24390,Q96JB2,Q10471,P57737,Q15392,P62070,O95197,Q96L58,P13591,Q9UHD1,Q9H4A6,Q86YR5,P11717,O15027,Q92896,O15260,Q8NF37,Q15363,Q92614,P33908,Q8IV08,O43505,Q13190,Q9H0V9,Q9UJU6,Q96S66,Q86SF2,Q9Y371,Q8TB61,Q08378
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
484,3,133,374,370,17,262,25,161,156,454,183,177,286,169,65,186,217,344,498,81,91,93,102,247,518,244,383,520,269,120
|
2917,578,2562,169,1248,1353,186,2396,93,2289,1732,2483,25,1256,1740,1368,3142,890,1853,286,156,1161,3,81,1386,1071,2666,1632,1991,1507,1509,2498,1076,2417,1873,603,2992,1079,2000,3093,370,907,1398,2115,2501,1282,2005,2994,262,1520,120,2607,374,2338,1524,914,915,102,484,2017,2747,2935,1667,344,17,919,2752,1799,383,1904,177,91,779,554,217,269,1318,858,498,65,1322,2368,133,161,244,2044,2537,2049,1116,2373,945,247,1700,183,2060,1459,2379,2380,1825,1712,1827,719,454,518,3103,958,1241,1720,1130,520,2388,1840
|
-1.0828695011676135,0.6434302553162722,-0.6515356333511229,1.3332432815151989,0.1493999725419618,0.08552503374798644,1.277907963516101,-0.5125776294717194,1.7105328972774696,-0.4439584005973705,-0.10910107725747438,-0.5817669225092277,3.111810995117898,0.1493999725419618,-0.10910107725747438,0.08552503374798644,-1.85525960192129,0.40009409100938204,-0.17500271918170665,1.0527824505275314,1.3882100669604411,0.21278718307129618,6.273729161291968,1.815231903298355,0.08552503374798644,0.2756939090187885,-0.7218933461099717,-0.04371782774137989,-0.24143086817602652,0.021154959123965873,0.021154959123965873,-0.5817669225092277,0.2756939090187885,-0.5125776294717194,-0.17500271918170665,0.6434302553162722,-1.2317465192005141,0.2756939090187885,-0.24143086817602652,-1.5376986032329918,0.8798200308586908,0.40009409100938204,0.08552503374798644,-0.30839382957997863,-0.5817669225092277,0.1493999725419618,-0.24143086817602652,-1.2317465192005141,1.1096416031090883,0.021154959123965873,1.550946556196765,-0.6515356333511229,0.8798200308586908,-0.4439584005973705,0.021154959123965873,0.40009409100938204,0.40009409100938204,1.657680089871788,0.7624690661744893,-0.24143086817602652,-0.7928498829766004,-1.0828695011676135,-0.04371782774137989,0.9378771015302817,3.5863493747714164,0.40009409100938204,-0.7928498829766004,-0.10910107725747438,0.8798200308586908,-0.17500271918170665,1.3332432815151989,1.7630487741502214,0.5226553678023891,0.7031636084840797,1.222199240405792,1.1096416031090883,0.1493999725419618,0.4616012571920667,0.7624690661744893,2.020717946656322,0.1493999725419618,-0.4439584005973705,1.4970570622608441,1.3882100669604411,1.1661121430364376,-0.24143086817602652,-0.5817669225092277,-0.24143086817602652,0.2756939090187885,-0.4439584005973705,0.40009409100938204,1.1661121430364376,-0.04371782774137989,1.3332432815151989,-0.24143086817602652,0.08552503374798644,-0.4439584005973705,-0.4439584005973705,-0.10910107725747438,-0.04371782774137989,-0.10910107725747438,0.5832629155020134,0.8213525930752211,0.7624690661744893,-1.5376986032329918,0.40009409100938204,0.21278718307129618,-0.04371782774137989,0.2756939090187885,0.7624690661744893,-0.4439584005973705,-0.10910107725747438
| 3,216
|
Ion transmembrane transporter activity
| 17
| 83
| 3.357545
| 0.000786
|
Q6P4Q7,Q9H2D1,P23634,P45880,Q70HW3,Q9HD20,O75964,Q96S66,Q93050,Q9Y487,P21796,O43772,P48047,Q13423,Q8TB61,Q9UDW1,P30825
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
212,1,36,69,7,42,189,244,12,45,77,15,79,83,269,125,208
|
726,729,1359,15,526,969,734,189,1055,1739,2399,1743,1613,2659,3161,3106,2721,1614,1970,2404,334,1747,1373,2489,832,1380,1621,974,1979,77,36,2093,2793,208,676,3051,3052,1272,69,1506,79,2217,2926,1875,1644,842,2960,1286,609,2230,83,765,2815,1677,1899,1539,212,7,1102,626,269,628,1554,12,303,3209,244,941,797,1,1025,2277,1818,42,515,125,1235,1589,958,1039,45,814,656
|
0.5226553678023891,0.5226553678023891,0.08552503374798644,4.152948119514853,0.7031636084840797,0.3381272349672459,0.5226553678023891,1.277907963516101,0.2756939090187885,-0.10910107725747438,-0.5125776294717194,-0.10910107725747438,-0.04371782774137989,-0.7218933461099717,-2.018669375001116,-1.6159672087429346,-0.7928498829766004,-0.04371782774137989,-0.24143086817602652,-0.5125776294717194,0.9378771015302817,-0.10910107725747438,0.08552503374798644,-0.5817669225092277,0.4616012571920667,0.08552503374798644,-0.04371782774137989,0.3381272349672459,-0.24143086817602652,1.8670863906456077,2.7948357651419897,-0.30839382957997863,-0.8644153121428026,1.222199240405792,0.5832629155020134,-1.3833236694797724,-1.3833236694797724,0.1493999725419618,1.9698254903525632,0.021154959123965873,1.8670863906456077,-0.37590010541019514,-1.0828695011676135,-0.17500271918170665,-0.04371782774137989,0.4616012571920667,-1.1569763978106686,0.1493999725419618,0.6434302553162722,-0.37590010541019514,1.815231903298355,0.5226553678023891,-0.8644153121428026,-0.04371782774137989,-0.17500271918170665,0.021154959123965873,1.222199240405792,4.791807119309899,0.2756939090187885,0.6434302553162722,1.1096416031090883,0.6434302553162722,0.021154959123965873,4.49741358097412,1.0527824505275314,-4.255425597507842,1.1661121430364376,0.40009409100938204,0.5226553678023891,7.395141724241461,0.3381272349672459,-0.37590010541019514,-0.10910107725747438,2.560673166001156,0.7624690661744893,1.550946556196765,0.21278718307129618,0.021154959123965873,0.40009409100938204,0.3381272349672459,2.4651035119965186,0.5226553678023891,0.6434302553162722
| 3,216
|
Dephosphorylation
| 30
| 95
| 3.317112
| 0.00091
|
Q5TFE4,Q13464,O00743,P04062,Q69YH5,Q9H2U2,Q9UHD1,P54098,Q06124,P18433,O60346,P49593,Q13555,Q99504,P12931,P63151,P62140,P62136,A6NDG6,P60510,Q969T7,Q16537,Q13614,Q86XL3,Q99956,Q9ULE6,Q8TF05,Q96JB5,P16333,Q96GX5
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
132,484,252,135,141,571,454,48,289,172,404,62,316,70,191,421,420,419,185,418,85,345,210,90,245,106,243,389,118,273
|
185,252,579,878,404,2186,2187,737,135,1153,1743,2196,2921,1974,191,2304,118,1858,172,2094,2096,1268,833,743,1987,2412,1991,2211,1637,62,2320,1996,1392,2218,48,418,419,420,3094,1774,421,2119,1402,1883,3130,1778,289,756,1524,1885,484,1529,316,210,2516,2437,1670,345,545,771,132,141,1302,90,1314,2895,2690,243,1206,1911,2625,85,936,1108,273,2694,389,1560,789,70,245,2533,1117,1573,571,1118,1701,1119,2162,1460,2379,454,106,1037,873
|
1.277907963516101,1.1096416031090883,0.6434302553162722,0.40009409100938204,0.8213525930752211,-0.37590010541019514,-0.37590010541019514,0.5226553678023891,1.4428130982976093,0.21278718307129618,-0.10910107725747438,-0.37590010541019514,-1.0828695011676135,-0.24143086817602652,1.277907963516101,-0.4439584005973705,1.550946556196765,-0.17500271918170665,1.3332432815151989,-0.30839382957997863,-0.30839382957997863,0.1493999725419618,0.4616012571920667,0.5226553678023891,-0.24143086817602652,-0.5125776294717194,-0.24143086817602652,-0.37590010541019514,-0.04371782774137989,2.1215677563097355,-0.4439584005973705,-0.24143086817602652,0.08552503374798644,-0.37590010541019514,2.3684078704596625,0.8213525930752211,0.8213525930752211,0.8213525930752211,-1.5376986032329918,-0.10910107725747438,0.8213525930752211,-0.30839382957997863,0.08552503374798644,-0.17500271918170665,-1.7747337369891967,-0.10910107725747438,1.0527824505275314,0.5226553678023891,0.021154959123965873,-0.17500271918170665,0.7624690661744893,0.021154959123965873,0.9955294106635983,1.222199240405792,-0.5817669225092277,-0.5125776294717194,-0.04371782774137989,0.9378771015302817,0.7031636084840797,0.5226553678023891,1.4970570622608441,1.4428130982976093,0.1493999725419618,1.7630487741502214,0.1493999725419618,-1.009414400019985,-0.7218933461099717,1.1661121430364376,0.21278718307129618,-0.17500271918170665,-0.6515356333511229,1.815231903298355,0.40009409100938204,0.2756939090187885,1.1096416031090883,-0.7218933461099717,0.8798200308586908,0.021154959123965873,0.5226553678023891,1.9698254903525632,1.1661121430364376,-0.5817669225092277,0.2756939090187885,0.021154959123965873,0.7031636084840797,0.2756939090187885,-0.04371782774137989,0.2756939090187885,-0.30839382957997863,0.08552503374798644,-0.4439584005973705,0.8213525930752211,1.657680089871788,0.3381272349672459,0.4616012571920667
| 3,216
|
Secondary alcohol metabolic process
| 6
| 37
| 3.286631
| 0.001014
|
P35610,Q14739,Q15392,Q15125,P48449,P37268
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
129,16,17,22,23,29
|
2184,3017,885,1608,1961,2192,135,1063,2663,896,1163,129,29,1635,23,1390,1391,1277,2419,2219,2002,1877,2227,1180,845,1410,2511,16,22,764,17,1092,1190,297,2273,2068,1588
|
-0.37590010541019514,-1.307191595712573,0.40009409100938204,-0.04371782774137989,-0.24143086817602652,-0.37590010541019514,1.4428130982976093,0.2756939090187885,-0.7218933461099717,0.40009409100938204,0.21278718307129618,1.4970570622608441,2.9774643320795486,-0.04371782774137989,3.41696171884832,0.08552503374798644,0.08552503374798644,0.1493999725419618,-0.5125776294717194,-0.37590010541019514,-0.24143086817602652,-0.17500271918170665,-0.37590010541019514,0.21278718307129618,0.4616012571920667,0.08552503374798644,-0.5817669225092277,3.711122412271352,3.459639186376742,0.5226553678023891,3.5863493747714164,0.2756939090187885,0.21278718307129618,1.0527824505275314,-0.37590010541019514,-0.24143086817602652,0.021154959123965873
| 3,216
|
Sterol metabolic process
| 6
| 32
| 3.24472
| 0.001176
|
P35610,Q14739,Q15392,Q15125,P48449,P37268
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
129,16,17,22,23,29
|
3017,885,1961,2192,135,1063,2663,896,1163,129,29,1635,23,1391,2219,2002,1877,2227,1180,845,1410,2511,16,22,764,17,1092,1190,297,2068,1588,2913
|
-1.307191595712573,0.40009409100938204,-0.24143086817602652,-0.37590010541019514,1.4428130982976093,0.2756939090187885,-0.7218933461099717,0.40009409100938204,0.21278718307129618,1.4970570622608441,2.9774643320795486,-0.04371782774137989,3.41696171884832,0.08552503374798644,-0.37590010541019514,-0.24143086817602652,-0.17500271918170665,-0.37590010541019514,0.21278718307129618,0.4616012571920667,0.08552503374798644,-0.5817669225092277,3.711122412271352,3.459639186376742,0.5226553678023891,3.5863493747714164,0.2756939090187885,0.21278718307129618,1.0527824505275314,-0.24143086817602652,0.021154959123965873,-1.009414400019985
| 3,216
|
Biological oxidations
| 26
| 49
| 3.221907
| 0.001273
|
Q9UI30,O95861,O43169,P16435,P05091,Q9HBK9,Q9NUJ1,P28161,O60701,P07099,Q8WUX2,O43488,P48506,P21964,P21266,O95340,Q969Z3,P78417,P11766,Q96IU4,Q9NUB1,Q9H2H9,Q99735,Q96DG6,Q8TB61,P48637
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
282,737,14,896,889,164,307,535,284,46,322,659,904,192,674,190,1013,194,829,502,356,1025,505,937,269,368
|
2647,2713,14,966,659,1482,284,1363,190,737,2192,889,46,2196,2088,829,1374,896,674,192,1163,2306,535,1630,1759,904,1508,368,194,1533,1190,1536,1795,269,322,1013,937,502,1109,1330,505,1025,164,356,307,1822,282,2171,1600
|
-0.7218933461099717,-0.7928498829766004,4.191950452921439,0.3381272349672459,0.5832629155020134,0.021154959123965873,1.0527824505275314,0.08552503374798644,1.277907963516101,0.5226553678023891,-0.37590010541019514,0.40009409100938204,2.4168980616095,-0.37590010541019514,-0.30839382957997863,0.4616012571920667,0.08552503374798644,0.40009409100938204,0.5832629155020134,1.277907963516101,0.21278718307129618,-0.4439584005973705,0.7031636084840797,-0.04371782774137989,-0.10910107725747438,0.40009409100938204,0.021154959123965873,0.8798200308586908,1.277907963516101,0.021154959123965873,0.21278718307129618,0.021154959123965873,-0.10910107725747438,1.1096416031090883,0.9955294106635983,0.3381272349672459,0.40009409100938204,0.7624690661744893,0.2756939090187885,0.1493999725419618,0.7624690661744893,0.3381272349672459,1.3882100669604411,0.9378771015302817,1.0527824505275314,-0.10910107725747438,1.1096416031090883,-0.30839382957997863,0.021154959123965873
| 3,216
|
Cholesterol metabolism with bloch and kandutschrussell pathways
| 6
| 22
| 3.156339
| 0.001598
|
P35610,Q14739,Q15392,Q15125,P48449,P37268
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
129,16,17,22,23,29
|
2561,1731,885,1965,824,2663,473,129,29,23,1995,1180,845,2511,16,22,764,17,1092,1190,275,2068
|
-0.6515356333511229,-0.10910107725747438,0.40009409100938204,-0.24143086817602652,0.4616012571920667,-0.7218933461099717,0.7624690661744893,1.4970570622608441,2.9774643320795486,3.41696171884832,-0.24143086817602652,0.21278718307129618,0.4616012571920667,-0.5817669225092277,3.711122412271352,3.459639186376742,0.5226553678023891,3.5863493747714164,0.2756939090187885,0.21278718307129618,1.1096416031090883,-0.24143086817602652
| 3,216
|
Trna modification
| 21
| 42
| 3.143127
| 0.001672
|
Q5VV42,Q9UI30,Q96BT7,O75648,Q96FX7,Q9BV44,Q7Z4G4,Q96EB1,Q2VPK5,Q7Z2T5,Q6P1R4,Q8WWH5,Q9Y2Z2,Q9UBP6,Q9NPF4,Q9H974,Q9UET6,O60294,Q9NX74,Q5T6V5,Q96G46
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
488,282,146,253,442,568,696,299,37,549,620,496,652,647,801,115,807,584,397,122,272
|
584,253,1486,2083,2213,1081,1085,1886,37,1793,122,488,620,1096,2023,549,696,496,1808,146,299,442,272,1690,1927,1021,568,1697,2942,115,798,1120,801,2066,397,1124,647,807,282,652,2173,1244
|
0.6434302553162722,1.1096416031090883,0.021154959123965873,-0.30839382957997863,-0.37590010541019514,0.2756939090187885,0.2756939090187885,-0.17500271918170665,2.7948357651419897,-0.10910107725747438,1.550946556196765,0.7624690661744893,0.6434302553162722,0.2756939090187885,-0.24143086817602652,0.7031636084840797,0.5832629155020134,0.7624690661744893,-0.10910107725747438,1.4428130982976093,1.0527824505275314,0.8213525930752211,1.1096416031090883,-0.04371782774137989,-0.17500271918170665,0.3381272349672459,0.7031636084840797,-0.04371782774137989,-1.0828695011676135,1.6044860903155633,0.5226553678023891,0.2756939090187885,0.5226553678023891,-0.24143086817602652,0.8798200308586908,0.2756939090187885,0.6434302553162722,0.5226553678023891,1.1096416031090883,0.6434302553162722,-0.30839382957997863,0.21278718307129618
| 3,216
|
Hormone metabolic process
| 10
| 28
| 3.136908
| 0.001707
|
P07858,Q6UWP2,O75844,O95340,Q8NBN7,Q9HB40,Q06124,O95470,Q92506,O60678
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
154,214,101,190,296,47,289,171,438,330
|
330,101,190,171,1743,154,1375,2199,896,2884,1767,2111,289,1790,1418,1095,214,296,1313,1549,438,1686,1021,47,450,2068,1036,653
|
0.9378771015302817,1.657680089871788,1.277907963516101,1.3332432815151989,-0.10910107725747438,1.3882100669604411,0.08552503374798644,-0.37590010541019514,0.40009409100938204,-1.009414400019985,-0.10910107725747438,-0.30839382957997863,1.0527824505275314,-0.10910107725747438,0.08552503374798644,0.2756939090187885,1.222199240405792,1.0527824505275314,0.1493999725419618,0.021154959123965873,0.8213525930752211,-0.04371782774137989,0.3381272349672459,2.4168980616095,0.8213525930752211,-0.24143086817602652,0.3381272349672459,0.6434302553162722
| 3,216
|
Protein processing
| 10
| 44
| 3.135216
| 0.001717
|
Q92896,P42575,Q5JRX3,O75844,P12931,Q9BXI6,Q15392,O75503,P55212,O14727
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
65,96,131,101,191,182,17,19,82,52
|
52,403,1481,1255,19,101,1609,589,1967,2661,3106,2302,191,1377,258,2305,1502,2210,96,1511,604,82,3053,1524,2124,1090,17,131,429,1898,2148,1203,65,1812,1686,1327,2045,791,182,1706,2705,1938,1345,2176
|
2.2705599514252803,0.8213525930752211,0.021154959123965873,0.1493999725419618,3.502094791440086,1.657680089871788,-0.04371782774137989,0.6434302553162722,-0.24143086817602652,-0.7218933461099717,-1.6159672087429346,-0.4439584005973705,1.277907963516101,0.08552503374798644,1.1096416031090883,-0.4439584005973705,0.021154959123965873,-0.37590010541019514,1.7105328972774696,0.021154959123965873,0.6434302553162722,1.815231903298355,-1.3833236694797724,0.021154959123965873,-0.30839382957997863,0.2756939090187885,3.5863493747714164,1.4970570622608441,0.8213525930752211,-0.17500271918170665,-0.30839382957997863,0.21278718307129618,2.020717946656322,-0.10910107725747438,-0.04371782774137989,0.1493999725419618,-0.24143086817602652,0.5226553678023891,1.3332432815151989,-0.04371782774137989,-0.7218933461099717,-0.17500271918170665,0.1493999725419618,-0.30839382957997863
| 3,216
|
Steroid metabolism
| 6
| 27
| 3.02145
| 0.002516
|
P35610,P04062,Q14739,Q15392,Q15125,P37268
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
129,135,16,17,22,29
|
3017,885,1961,2192,135,2663,1163,129,29,2002,1877,2227,1180,845,1410,2511,16,22,764,17,1092,1190,214,1021,2068,1588,2913
|
-1.307191595712573,0.40009409100938204,-0.24143086817602652,-0.37590010541019514,1.4428130982976093,-0.7218933461099717,0.21278718307129618,1.4970570622608441,2.9774643320795486,-0.24143086817602652,-0.17500271918170665,-0.37590010541019514,0.21278718307129618,0.4616012571920667,0.08552503374798644,-0.5817669225092277,3.711122412271352,3.459639186376742,0.5226553678023891,3.5863493747714164,0.2756939090187885,0.21278718307129618,1.222199240405792,0.3381272349672459,-0.24143086817602652,0.021154959123965873,-1.009414400019985
| 3,216
|
Phosphoprotein phosphatase activity
| 17
| 42
| 3.001869
| 0.002683
|
Q13555,Q99504,Q99956,P62140,P62136,A6NDG6,P60510,O00743,Q8TF05,P54098,Q9ULE6,Q06124,P18433,O60346,Q13614,Q9H2U2,P49593
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
316,70,245,420,419,185,418,252,243,48,106,289,172,404,210,571,62
|
185,252,878,404,2187,1974,1858,172,2094,833,2412,62,1392,2218,48,418,419,420,1778,289,756,1885,316,210,2516,2437,545,1314,243,1206,1911,1108,2694,70,245,2533,1117,571,1119,106,1037,873
|
1.277907963516101,1.1096416031090883,0.40009409100938204,0.8213525930752211,-0.37590010541019514,-0.24143086817602652,-0.17500271918170665,1.3332432815151989,-0.30839382957997863,0.4616012571920667,-0.5125776294717194,2.1215677563097355,0.08552503374798644,-0.37590010541019514,2.3684078704596625,0.8213525930752211,0.8213525930752211,0.8213525930752211,-0.10910107725747438,1.0527824505275314,0.5226553678023891,-0.17500271918170665,0.9955294106635983,1.222199240405792,-0.5817669225092277,-0.5125776294717194,0.7031636084840797,0.1493999725419618,1.1661121430364376,0.21278718307129618,-0.17500271918170665,0.2756939090187885,-0.7218933461099717,1.9698254903525632,1.1661121430364376,-0.5817669225092277,0.2756939090187885,0.7031636084840797,0.2756939090187885,1.657680089871788,0.3381272349672459,0.4616012571920667
| 3,216
|
Peptidyl tyrosine dephosphorylation
| 7
| 18
| 2.997698
| 0.00272
|
Q99504,Q99956,Q9ULE6,A6NDG6,P54098,P18433,Q13614
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
70,245,106,185,48,172,210
|
185,2187,1974,1858,172,2094,1392,48,289,1885,210,545,1314,1206,70,245,106,873
|
1.277907963516101,-0.37590010541019514,-0.24143086817602652,-0.17500271918170665,1.3332432815151989,-0.30839382957997863,0.08552503374798644,2.3684078704596625,1.0527824505275314,-0.17500271918170665,1.222199240405792,0.7031636084840797,0.1493999725419618,0.21278718307129618,1.9698254903525632,1.1661121430364376,1.657680089871788,0.4616012571920667
| 3,216
|
Protein tyrosine phosphatase activity
| 7
| 18
| 2.997698
| 0.00272
|
Q99504,Q99956,Q9ULE6,A6NDG6,P54098,P18433,Q13614
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
70,245,106,185,48,172,210
|
185,2187,1974,1858,172,2094,1392,48,289,1885,210,545,1314,1206,70,245,106,873
|
1.277907963516101,-0.37590010541019514,-0.24143086817602652,-0.17500271918170665,1.3332432815151989,-0.30839382957997863,0.08552503374798644,2.3684078704596625,1.0527824505275314,-0.17500271918170665,1.222199240405792,0.7031636084840797,0.1493999725419618,0.21278718307129618,1.9698254903525632,1.1661121430364376,1.657680089871788,0.4616012571920667
| 3,216
|
Transporter activity
| 22
| 135
| 2.970529
| 0.002973
|
Q9NS69,Q9H2D1,Q70HW3,Q93050,O43772,P04062,O60830,Q96NB2,P23634,O43674,Q9HD20,Q9Y487,P45880,O75964,P21796,P48047,Q13423,P30825,Q6P4Q7,Q96S66,Q9UDW1,Q8TB61
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
0,1,7,12,15,135,21,303,36,151,42,45,69,189,77,79,83,208,212,244,125,269
|
2917,726,2650,729,2780,151,1954,1359,15,526,21,2293,2953,662,1144,1605,969,734,189,887,2295,2568,1055,1148,1739,2838,1488,2399,135,1743,1613,2659,3161,3106,2721,1614,1970,2404,334,1747,1373,2489,832,2955,897,1380,1621,974,1979,77,1161,36,2093,2793,2097,1498,2884,208,676,3051,3052,1272,69,1506,79,1509,1076,477,1280,2214,2322,2217,2926,1875,1644,842,2960,1877,1286,609,2673,2230,1084,83,2677,765,2244,1415,2815,1677,1899,1539,212,7,1102,1430,1547,626,269,628,297,1554,12,1441,303,3209,244,1444,1214,2045,941,791,796,797,2541,1,1025,2277,1818,42,1820,0,515,125,1469,1235,1589,958,1126,1039,45,2710,814,656,3104
|
-1.0828695011676135,0.5226553678023891,-0.7218933461099717,0.5226553678023891,-0.8644153121428026,1.3882100669604411,-0.24143086817602652,0.08552503374798644,4.152948119514853,0.7031636084840797,3.459639186376742,-0.4439584005973705,-1.1569763978106686,0.5832629155020134,0.21278718307129618,-0.04371782774137989,0.3381272349672459,0.5226553678023891,1.277907963516101,0.40009409100938204,-0.4439584005973705,-0.6515356333511229,0.2756939090187885,0.21278718307129618,-0.10910107725747438,-0.9365999560555965,0.021154959123965873,-0.5125776294717194,1.4428130982976093,-0.10910107725747438,-0.04371782774137989,-0.7218933461099717,-2.018669375001116,-1.6159672087429346,-0.7928498829766004,-0.04371782774137989,-0.24143086817602652,-0.5125776294717194,0.9378771015302817,-0.10910107725747438,0.08552503374798644,-0.5817669225092277,0.4616012571920667,-1.1569763978106686,0.40009409100938204,0.08552503374798644,-0.04371782774137989,0.3381272349672459,-0.24143086817602652,1.8670863906456077,0.21278718307129618,2.7948357651419897,-0.30839382957997863,-0.8644153121428026,-0.30839382957997863,0.021154959123965873,-1.009414400019985,1.222199240405792,0.5832629155020134,-1.3833236694797724,-1.3833236694797724,0.1493999725419618,1.9698254903525632,0.021154959123965873,1.8670863906456077,0.021154959123965873,0.2756939090187885,0.7624690661744893,0.1493999725419618,-0.37590010541019514,-0.4439584005973705,-0.37590010541019514,-1.0828695011676135,-0.17500271918170665,-0.04371782774137989,0.4616012571920667,-1.1569763978106686,-0.17500271918170665,0.1493999725419618,0.6434302553162722,-0.7218933461099717,-0.37590010541019514,0.2756939090187885,1.815231903298355,-0.7218933461099717,0.5226553678023891,-0.37590010541019514,0.08552503374798644,-0.8644153121428026,-0.04371782774137989,-0.17500271918170665,0.021154959123965873,1.222199240405792,4.791807119309899,0.2756939090187885,0.08552503374798644,0.021154959123965873,0.6434302553162722,1.1096416031090883,0.6434302553162722,1.0527824505275314,0.021154959123965873,4.49741358097412,0.08552503374798644,1.0527824505275314,-4.255425597507842,1.1661121430364376,0.08552503374798644,0.21278718307129618,-0.24143086817602652,0.40009409100938204,0.5226553678023891,0.5226553678023891,0.5226553678023891,-0.5817669225092277,7.395141724241461,0.3381272349672459,-0.37590010541019514,-0.10910107725747438,2.560673166001156,-0.10910107725747438,8.262121890752995,0.7624690661744893,1.550946556196765,0.08552503374798644,0.21278718307129618,0.021154959123965873,0.40009409100938204,0.2756939090187885,0.3381272349672459,2.4651035119965186,-0.7218933461099717,0.5226553678023891,0.6434302553162722,-1.5376986032329918
| 3,216
|
Steroid metabolic process
| 10
| 60
| 2.953435
| 0.003143
|
Q6UWP2,P35610,P04062,Q14739,Q15392,O95470,Q15125,P48449,P37268,Q6IAA8
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
214,129,135,16,17,171,22,23,29,211
|
1352,3017,885,1961,171,2192,135,1743,468,1063,2663,2199,896,1161,3023,1163,1756,2097,2884,129,29,1635,23,1391,984,2111,2219,2002,1877,2227,1180,845,2121,1410,685,2511,16,22,764,17,2348,1790,1092,1190,1418,211,214,1313,297,438,1438,1444,1021,1930,1700,2068,1588,573,2913,1036
|
0.08552503374798644,-1.307191595712573,0.40009409100938204,-0.24143086817602652,1.3332432815151989,-0.37590010541019514,1.4428130982976093,-0.10910107725747438,0.7624690661744893,0.2756939090187885,-0.7218933461099717,-0.37590010541019514,0.40009409100938204,0.21278718307129618,-1.307191595712573,0.21278718307129618,-0.10910107725747438,-0.30839382957997863,-1.009414400019985,1.4970570622608441,2.9774643320795486,-0.04371782774137989,3.41696171884832,0.08552503374798644,0.3381272349672459,-0.30839382957997863,-0.37590010541019514,-0.24143086817602652,-0.17500271918170665,-0.37590010541019514,0.21278718307129618,0.4616012571920667,-0.30839382957997863,0.08552503374798644,0.5832629155020134,-0.5817669225092277,3.711122412271352,3.459639186376742,0.5226553678023891,3.5863493747714164,-0.4439584005973705,-0.10910107725747438,0.2756939090187885,0.21278718307129618,0.08552503374798644,1.222199240405792,1.222199240405792,0.1493999725419618,1.0527824505275314,0.8213525930752211,0.08552503374798644,0.08552503374798644,0.3381272349672459,-0.17500271918170665,-0.04371782774137989,-0.24143086817602652,0.021154959123965873,0.7031636084840797,-1.009414400019985,0.3381272349672459
| 3,216
|
Phosphatase activity
| 19
| 60
| 2.949122
| 0.003187
|
Q5TFE4,O00743,Q9H2U2,P54098,Q06124,P18433,O60346,P49593,Q13555,Q99504,P62140,P62136,A6NDG6,P60510,Q969T7,Q13614,Q99956,Q8TF05,Q9ULE6
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
132,252,571,48,289,172,404,62,316,70,420,419,185,418,85,210,245,243,106
|
185,252,878,404,2187,737,1743,1974,1858,172,2094,1268,833,2412,62,1996,1392,2218,48,418,419,420,1883,1778,289,756,1524,1885,316,210,2516,2437,1670,545,132,1314,2690,243,1206,1911,85,936,1108,2694,789,70,245,2533,708,1117,1573,571,1118,1701,1119,2162,2379,106,1037,873
|
1.277907963516101,1.1096416031090883,0.40009409100938204,0.8213525930752211,-0.37590010541019514,0.5226553678023891,-0.10910107725747438,-0.24143086817602652,-0.17500271918170665,1.3332432815151989,-0.30839382957997863,0.1493999725419618,0.4616012571920667,-0.5125776294717194,2.1215677563097355,-0.24143086817602652,0.08552503374798644,-0.37590010541019514,2.3684078704596625,0.8213525930752211,0.8213525930752211,0.8213525930752211,-0.17500271918170665,-0.10910107725747438,1.0527824505275314,0.5226553678023891,0.021154959123965873,-0.17500271918170665,0.9955294106635983,1.222199240405792,-0.5817669225092277,-0.5125776294717194,-0.04371782774137989,0.7031636084840797,1.4970570622608441,0.1493999725419618,-0.7218933461099717,1.1661121430364376,0.21278718307129618,-0.17500271918170665,1.815231903298355,0.40009409100938204,0.2756939090187885,-0.7218933461099717,0.5226553678023891,1.9698254903525632,1.1661121430364376,-0.5817669225092277,0.5832629155020134,0.2756939090187885,0.021154959123965873,0.7031636084840797,0.2756939090187885,-0.04371782774137989,0.2756939090187885,-0.30839382957997863,-0.4439584005973705,1.657680089871788,0.3381272349672459,0.4616012571920667
| 3,216
|
Lytic vacuole organization
| 8
| 24
| 2.93846
| 0.003298
|
Q9BZG1,Q9P253,P50897,Q9UJC3,P04062,O75503,O14773,Q6IAA8
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
134,33,130,76,135,19,117,211
|
1602,117,19,1256,135,2488,2662,744,1991,130,2321,235,2005,2807,2747,211,1918,2040,1561,134,2466,33,76,2871
|
-0.04371782774137989,1.550946556196765,3.502094791440086,0.1493999725419618,1.4428130982976093,-0.5817669225092277,-0.7218933461099717,0.5226553678023891,-0.24143086817602652,1.4970570622608441,-0.4439584005973705,1.1661121430364376,-0.24143086817602652,-0.8644153121428026,-0.7928498829766004,1.222199240405792,-0.17500271918170665,-0.24143086817602652,0.021154959123965873,1.4970570622608441,-0.5125776294717194,2.886659085145426,1.9186162670977254,-0.9365999560555965
| 3,216
|
Protein phosphatase
| 10
| 25
| 2.879613
| 0.003982
|
Q99504,Q99956,P62140,P62136,A6NDG6,O00743,Q06124,P18433,O60346,P49593
|
Functions
|
Protein Atlas Molecular function
|
protein_atlas_molecular_function
|
70,245,420,419,185,252,289,172,404,62
|
185,252,878,404,2187,1974,1858,172,2094,2412,62,1392,2218,418,419,420,1778,289,756,1885,1206,1911,70,245,1117
|
1.277907963516101,1.1096416031090883,0.40009409100938204,0.8213525930752211,-0.37590010541019514,-0.24143086817602652,-0.17500271918170665,1.3332432815151989,-0.30839382957997863,-0.5125776294717194,2.1215677563097355,0.08552503374798644,-0.37590010541019514,0.8213525930752211,0.8213525930752211,0.8213525930752211,-0.10910107725747438,1.0527824505275314,0.5226553678023891,-0.17500271918170665,0.21278718307129618,-0.17500271918170665,1.9698254903525632,1.1661121430364376,0.2756939090187885
| 3,216
|
transporter
| 6
| 53
| 2.878327
| 0.003998
|
Q9H2D1,Q9HD45,O43772,O60830,Q567V2,Q99805
|
Functions
|
Panther Protein class
|
panther_protein_class
|
1,116,15,21,30,63
|
727,462,1137,2562,2563,1604,581,1358,1359,15,405,21,2079,1848,2495,834,1509,2415,603,159,2322,2217,2926,1394,1396,906,1771,2960,2961,1412,30,2818,2446,1102,1431,1316,1007,271,1320,1439,1689,1214,63,941,2370,3115,1,800,116,2552,1236,1938,1944
|
0.5226553678023891,0.7624690661744893,0.21278718307129618,-0.6515356333511229,-0.6515356333511229,-0.04371782774137989,0.6434302553162722,0.08552503374798644,0.08552503374798644,4.152948119514853,0.8213525930752211,3.459639186376742,-0.30839382957997863,-0.17500271918170665,-0.5817669225092277,0.4616012571920667,0.021154959123965873,-0.5125776294717194,0.6434302553162722,1.3882100669604411,-0.4439584005973705,-0.37590010541019514,-1.0828695011676135,0.08552503374798644,0.08552503374798644,0.40009409100938204,-0.10910107725747438,-1.1569763978106686,-1.1569763978106686,0.08552503374798644,2.9774643320795486,-0.8644153121428026,-0.5125776294717194,0.2756939090187885,0.08552503374798644,0.1493999725419618,0.3381272349672459,1.1096416031090883,0.1493999725419618,0.08552503374798644,-0.04371782774137989,0.21278718307129618,2.0712974525073755,0.40009409100938204,-0.4439584005973705,-1.6159672087429346,7.395141724241461,0.5226553678023891,1.6044860903155633,-0.5817669225092277,0.21278718307129618,-0.17500271918170665,-0.17500271918170665
| 3,216
|
er
| 12
| 84
| 2.867494
| 0.004137
|
O96005,Q969V3,Q13190,Q9Y487,Q8NC56,Q8NHH9,Q14739,Q15392,Q8NF37,O95470,Q15125,P48449
|
Localization
|
OpenCell Localization
|
opencell_localization
|
35,6,102,45,145,178,16,17,217,171,22,23
|
1478,2561,2393,876,877,1356,1844,2483,885,3086,1610,171,1611,35,2192,2299,1490,1852,364,2201,1627,2202,1868,1638,23,3150,1076,1998,1873,538,2596,841,2501,1282,3108,1650,2120,2226,2429,542,1654,2850,102,16,3058,1530,22,344,17,1092,616,1190,2937,2442,1899,550,2140,2258,145,217,178,2897,2623,2759,1318,1807,6,559,2627,1441,1442,2044,2371,2541,2465,224,2774,2379,1825,1712,958,1837,45,1476
|
0.021154959123965873,-0.6515356333511229,-0.5125776294717194,0.40009409100938204,0.40009409100938204,0.08552503374798644,-0.17500271918170665,-0.5817669225092277,0.40009409100938204,-1.5376986032329918,-0.04371782774137989,1.3332432815151989,-0.04371782774137989,2.7948357651419897,-0.37590010541019514,-0.4439584005973705,0.021154959123965873,-0.17500271918170665,0.8798200308586908,-0.37590010541019514,-0.04371782774137989,-0.37590010541019514,-0.17500271918170665,-0.04371782774137989,3.41696171884832,-1.9365664874383406,0.2756939090187885,-0.24143086817602652,-0.17500271918170665,0.7031636084840797,-0.6515356333511229,0.4616012571920667,-0.5817669225092277,0.1493999725419618,-1.6159672087429346,-0.04371782774137989,-0.30839382957997863,-0.37590010541019514,-0.5125776294717194,0.7031636084840797,-0.04371782774137989,-0.9365999560555965,1.657680089871788,3.711122412271352,-1.3833236694797724,0.021154959123965873,3.459639186376742,0.9378771015302817,3.5863493747714164,0.2756939090187885,0.6434302553162722,0.21278718307129618,-1.0828695011676135,-0.5125776294717194,-0.17500271918170665,0.7031636084840797,-0.30839382957997863,-0.37590010541019514,1.4428130982976093,1.222199240405792,1.3332432815151989,-1.009414400019985,-0.6515356333511229,-0.7928498829766004,0.1493999725419618,-0.10910107725747438,5.075890701055905,0.7031636084840797,-0.6515356333511229,0.08552503374798644,0.08552503374798644,-0.24143086817602652,-0.4439584005973705,-0.5817669225092277,-0.5125776294717194,1.222199240405792,-0.7928498829766004,-0.4439584005973705,-0.10910107725747438,-0.04371782774137989,0.40009409100938204,-0.10910107725747438,2.4651035119965186,0.08552503374798644
| 3,216
|
Deubiquitination
| 30
| 93
| 2.840707
| 0.004501
|
Q06323,P55036,P25789,P25787,Q14694,Q96FW1,P28070,P54578,O15294,Q6GQQ9,P49720,Q9NWV8,P49721,P55072,Q9NXR7,P60900,P28072,P45880,P38398,Q13309,P21796,Q8NB78,Q9Y5K5,Q96RU2,Q9UL46,Q86UV5,O43242,Q9Y265,P43686,P85037
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
612,480,595,366,613,441,136,174,403,199,414,203,64,538,204,539,193,69,68,314,77,352,359,218,248,384,463,398,474,119
|
962,816,1726,2479,3015,403,463,1361,1607,887,1366,1367,1612,1370,1375,1064,1496,77,2095,366,1068,595,1861,136,193,898,2795,1169,68,2987,474,69,835,1639,414,64,1641,2732,174,2801,480,538,539,988,1648,2423,606,908,119,612,2234,1659,314,1528,2235,2962,918,1295,613,3075,2130,1091,1670,1299,199,930,384,1002,352,1005,783,2692,2266,1012,441,1924,218,1813,1328,1446,203,204,1822,248,2643,1346,1832,1833,398,1039,2075,2389,359
|
0.3381272349672459,0.4616012571920667,-0.10910107725747438,-0.5817669225092277,-1.307191595712573,0.8213525930752211,0.7624690661744893,0.08552503374798644,-0.04371782774137989,0.40009409100938204,0.08552503374798644,0.08552503374798644,-0.04371782774137989,0.08552503374798644,0.08552503374798644,0.2756939090187885,0.021154959123965873,1.8670863906456077,-0.30839382957997863,0.8798200308586908,0.2756939090187885,0.6434302553162722,-0.17500271918170665,1.4428130982976093,1.277907963516101,0.40009409100938204,-0.8644153121428026,0.21278718307129618,1.9698254903525632,-1.2317465192005141,0.7624690661744893,1.9698254903525632,0.4616012571920667,-0.04371782774137989,0.8213525930752211,2.020717946656322,-0.04371782774137989,-0.7928498829766004,1.3332432815151989,-0.8644153121428026,0.7624690661744893,0.7031636084840797,0.7031636084840797,0.3381272349672459,-0.04371782774137989,-0.5125776294717194,0.6434302553162722,0.40009409100938204,1.550946556196765,0.6434302553162722,-0.37590010541019514,-0.04371782774137989,0.9955294106635983,0.021154959123965873,-0.37590010541019514,-1.1569763978106686,0.40009409100938204,0.1493999725419618,0.6434302553162722,-1.460155105498623,-0.30839382957997863,0.2756939090187885,-0.04371782774137989,0.1493999725419618,1.277907963516101,0.40009409100938204,0.8798200308586908,0.3381272349672459,0.9378771015302817,0.3381272349672459,0.5226553678023891,-0.7218933461099717,-0.37590010541019514,0.3381272349672459,0.8213525930752211,-0.17500271918170665,1.222199240405792,-0.10910107725747438,0.1493999725419618,0.08552503374798644,1.277907963516101,1.277907963516101,-0.10910107725747438,1.1661121430364376,-0.6515356333511229,0.1493999725419618,-0.10910107725747438,-0.10910107725747438,0.8798200308586908,0.3381272349672459,-0.24143086817602652,-0.4439584005973705,0.9378771015302817
| 3,216
|
Cysteine protease
| 25
| 49
| 2.838171
| 0.004537
|
Q14694,Q01804,P55210,P17655,Q96FW1,P07858,Q9Y4P1,Q9NVG8,Q9BXI6,P49915,P54578,Q6GQQ9,P17812,O60343,Q13510,Q06210,P55212,Q96RU2,Q9Y5K5,Q99497,Q92820,O15484,P42575,Q4KMP7,Q9NRF8
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
613,372,604,258,441,154,310,184,182,415,174,199,672,661,685,684,82,218,359,790,785,329,96,242,395
|
329,661,1364,1366,1492,154,2197,258,672,1163,1984,2987,2210,96,835,415,839,174,604,82,2597,372,1183,684,685,2744,1297,613,242,2616,1192,199,3079,1006,1434,785,1012,441,1924,218,790,182,395,184,2912,1832,811,310,359
|
0.9378771015302817,0.5832629155020134,0.08552503374798644,0.08552503374798644,0.021154959123965873,1.3882100669604411,-0.37590010541019514,1.1096416031090883,0.5832629155020134,0.21278718307129618,-0.24143086817602652,-1.2317465192005141,-0.37590010541019514,1.7105328972774696,0.4616012571920667,0.8213525930752211,0.4616012571920667,1.3332432815151989,0.6434302553162722,1.815231903298355,-0.6515356333511229,0.8798200308586908,0.21278718307129618,0.5832629155020134,0.5832629155020134,-0.7928498829766004,0.1493999725419618,0.6434302553162722,1.1661121430364376,-0.6515356333511229,0.21278718307129618,1.277907963516101,-1.460155105498623,0.3381272349672459,0.08552503374798644,0.5226553678023891,0.3381272349672459,0.8213525930752211,-0.17500271918170665,1.222199240405792,0.5226553678023891,1.3332432815151989,0.8798200308586908,1.3332432815151989,-1.009414400019985,-0.10910107725747438,0.5226553678023891,1.0527824505275314,0.9378771015302817
| 3,216
|
Phosphoric ester hydrolase activity
| 22
| 72
| 2.826801
| 0.004702
|
Q5TFE4,O00743,Q9H2U2,Q9Y3Z3,P54098,Q06124,P27695,O60346,P18433,P49593,Q13555,Q99504,P62140,P62136,A6NDG6,P60510,Q969T7,Q13614,Q8IV08,Q99956,Q8TF05,Q9ULE6
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
132,252,571,577,48,289,534,404,172,62,316,70,420,419,185,418,85,210,91,245,243,106
|
185,252,878,404,2187,1149,737,1743,2086,740,1974,1858,172,1066,2094,534,1268,2311,833,2412,62,1996,1392,2218,48,418,419,420,1883,1181,1778,289,756,1524,1885,316,210,2516,2437,1670,1535,545,132,91,2894,1314,2690,243,1206,1911,85,936,1108,2694,789,70,245,2533,708,1117,1573,571,1118,1701,1119,2162,2379,2380,106,1037,873,577
|
1.277907963516101,1.1096416031090883,0.40009409100938204,0.8213525930752211,-0.37590010541019514,0.21278718307129618,0.5226553678023891,-0.10910107725747438,-0.30839382957997863,0.5226553678023891,-0.24143086817602652,-0.17500271918170665,1.3332432815151989,0.2756939090187885,-0.30839382957997863,0.7031636084840797,0.1493999725419618,-0.4439584005973705,0.4616012571920667,-0.5125776294717194,2.1215677563097355,-0.24143086817602652,0.08552503374798644,-0.37590010541019514,2.3684078704596625,0.8213525930752211,0.8213525930752211,0.8213525930752211,-0.17500271918170665,0.21278718307129618,-0.10910107725747438,1.0527824505275314,0.5226553678023891,0.021154959123965873,-0.17500271918170665,0.9955294106635983,1.222199240405792,-0.5817669225092277,-0.5125776294717194,-0.04371782774137989,0.021154959123965873,0.7031636084840797,1.4970570622608441,1.7630487741502214,-1.009414400019985,0.1493999725419618,-0.7218933461099717,1.1661121430364376,0.21278718307129618,-0.17500271918170665,1.815231903298355,0.40009409100938204,0.2756939090187885,-0.7218933461099717,0.5226553678023891,1.9698254903525632,1.1661121430364376,-0.5817669225092277,0.5832629155020134,0.2756939090187885,0.021154959123965873,0.7031636084840797,0.2756939090187885,-0.04371782774137989,0.2756939090187885,-0.30839382957997863,-0.4439584005973705,-0.4439584005973705,1.657680089871788,0.3381272349672459,0.4616012571920667,0.7031636084840797
| 3,216
|
SH3-like domain superfamily [IPR036028]
| 12
| 26
| 2.823646
| 0.004748
|
Q9UJU6,P12931,Q9UDY2,Q9Y5K6,P46109,Q9Y5X1,P07948,P07947,Q15642,Q92796,P16333,Q9UQB8
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
518,191,43,459,78,80,256,406,27,323,118,31
|
1140,406,256,191,118,1066,1273,78,2427,2738,2743,3074,1088,27,1673,323,942,2945,43,518,1239,1126,31,520,459,80
|
0.21278718307129618,0.8213525930752211,1.1096416031090883,1.277907963516101,1.550946556196765,0.2756939090187885,0.1493999725419618,1.8670863906456077,-0.5125776294717194,-0.7928498829766004,-0.7928498829766004,-1.460155105498623,0.2756939090187885,3.022492044155325,-0.04371782774137989,0.9955294106635983,0.40009409100938204,-1.0828695011676135,2.5130274793029668,0.7624690661744893,0.21278718307129618,0.2756939090187885,2.932187583429893,0.7624690661744893,0.8213525930752211,1.8670863906456077
| 3,216
|
protein phosphatase
| 10
| 22
| 2.823345
| 0.004753
|
Q99956,P63151,P62140,P62136,Q9ULE6,O00743,Q06124,P18433,Q16537,P49593
|
Functions
|
Panther Protein class
|
panther_protein_class
|
245,421,420,419,106,252,289,172,345,62
|
252,878,1974,1858,172,2094,2412,62,2218,418,419,420,421,289,756,1885,2516,1670,345,245,1117,106
|
1.1096416031090883,0.40009409100938204,-0.24143086817602652,-0.17500271918170665,1.3332432815151989,-0.30839382957997863,-0.5125776294717194,2.1215677563097355,-0.37590010541019514,0.8213525930752211,0.8213525930752211,0.8213525930752211,0.8213525930752211,1.0527824505275314,0.5226553678023891,-0.17500271918170665,-0.5817669225092277,-0.04371782774137989,0.9378771015302817,1.1661121430364376,0.2756939090187885,1.657680089871788
| 3,216
|
Protein o linked glycosylation
| 7
| 13
| 2.813843
| 0.004895
|
O60502,O43505,Q86SF2,Q10471,Q9H488,O15294,Q6ZXV5
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
34,93,383,374,50,403,292
|
1351,403,93,34,1048,1843,466,1287,374,292,1902,383,50
|
0.08552503374798644,0.8213525930752211,1.7105328972774696,2.8408760799008674,0.2756939090187885,-0.17500271918170665,0.7624690661744893,0.1493999725419618,0.8798200308586908,1.0527824505275314,-0.17500271918170665,0.8798200308586908,2.3196296243830314
| 3,216
|
Alcohol biosynthetic process
| 7
| 37
| 2.795863
| 0.005176
|
P04062,Q14739,Q15392,Q92551,Q15125,P48449,P37268
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
135,16,17,123,22,23,29
|
185,876,877,3017,885,1961,2192,135,3090,1063,2663,896,2883,1268,1384,29,1635,23,2219,2002,2847,1180,845,1410,685,2511,16,22,764,17,1092,769,1190,123,790,1228,2068
|
1.277907963516101,0.40009409100938204,0.40009409100938204,-1.307191595712573,0.40009409100938204,-0.24143086817602652,-0.37590010541019514,1.4428130982976093,-1.5376986032329918,0.2756939090187885,-0.7218933461099717,0.40009409100938204,-1.009414400019985,0.1493999725419618,0.08552503374798644,2.9774643320795486,-0.04371782774137989,3.41696171884832,-0.37590010541019514,-0.24143086817602652,-0.9365999560555965,0.21278718307129618,0.4616012571920667,0.08552503374798644,0.5832629155020134,-0.5817669225092277,3.711122412271352,3.459639186376742,0.5226553678023891,3.5863493747714164,0.2756939090187885,0.5226553678023891,0.21278718307129618,1.550946556196765,0.5226553678023891,0.21278718307129618,-0.24143086817602652
| 3,216
|
Trna modification in the nucleus and cytosol
| 12
| 22
| 2.778711
| 0.005458
|
Q9UBP6,Q5VV42,Q2VPK5,Q9UI30,Q96BT7,Q9H974,O75648,Q96FX7,Q9UET6,O60294,Q9NX74,Q7Z4G4
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
647,488,37,282,146,115,253,442,807,584,397,696
|
584,253,2085,1081,1085,37,488,1096,696,146,442,1690,1326,115,801,2066,397,647,807,282,2173,1244
|
0.6434302553162722,1.1096416031090883,-0.30839382957997863,0.2756939090187885,0.2756939090187885,2.7948357651419897,0.7624690661744893,0.2756939090187885,0.5832629155020134,1.4428130982976093,0.8213525930752211,-0.04371782774137989,0.1493999725419618,1.6044860903155633,0.5226553678023891,-0.24143086817602652,0.8798200308586908,0.6434302553162722,0.5226553678023891,1.1096416031090883,-0.30839382957997863,0.21278718307129618
| 3,216
|
Phase ii conjugation of compounds
| 12
| 32
| 2.770001
| 0.005606
|
P48637,Q9NUJ1,P21964,Q9UI30,O95340,O60701,P78417,Q96IU4,Q99735,Q8TB61,Q8WUX2,Q9HBK9
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
368,307,192,282,190,284,194,502,505,269,322,164
|
2713,966,1482,284,1363,190,737,2088,1374,674,192,2306,535,1759,904,1508,368,194,1536,269,322,502,1109,1330,505,1025,164,307,1822,282,2171,1600
|
-0.7928498829766004,0.3381272349672459,0.021154959123965873,1.0527824505275314,0.08552503374798644,1.277907963516101,0.5226553678023891,-0.30839382957997863,0.08552503374798644,0.5832629155020134,1.277907963516101,-0.4439584005973705,0.7031636084840797,-0.10910107725747438,0.40009409100938204,0.021154959123965873,0.8798200308586908,1.277907963516101,0.021154959123965873,1.1096416031090883,0.9955294106635983,0.7624690661744893,0.2756939090187885,0.1493999725419618,0.7624690661744893,0.3381272349672459,1.3882100669604411,1.0527824505275314,-0.10910107725747438,1.1096416031090883,-0.30839382957997863,0.021154959123965873
| 3,216
|
SH3 domain [IPR001452]
| 12
| 29
| 2.76158
| 0.005752
|
Q9UJU6,P12931,Q9UDY2,Q9Y5K6,P46109,Q9Y5X1,P07948,P07947,Q15642,Q92796,P16333,Q9UQB8
|
Sequence
|
InterPro Domain
|
interpro_domain
|
518,191,43,459,78,80,256,406,27,323,118,31
|
1140,406,256,191,1376,118,1066,1273,78,2427,2738,2743,3074,1088,1532,27,1673,323,942,2945,43,518,1239,1126,3047,31,520,459,80
|
0.21278718307129618,0.8213525930752211,1.1096416031090883,1.277907963516101,0.08552503374798644,1.550946556196765,0.2756939090187885,0.1493999725419618,1.8670863906456077,-0.5125776294717194,-0.7928498829766004,-0.7928498829766004,-1.460155105498623,0.2756939090187885,0.021154959123965873,3.022492044155325,-0.04371782774137989,0.9955294106635983,0.40009409100938204,-1.0828695011676135,2.5130274793029668,0.7624690661744893,0.21278718307129618,0.2756939090187885,-1.307191595712573,2.932187583429893,0.7624690661744893,0.8213525930752211,1.8670863906456077
| 3,216
|
Protein maturation
| 18
| 69
| 2.736252
| 0.006214
|
Q92896,P42575,Q5JRX3,O75844,P12931,Q9BXI6,Q10471,O76071,Q15392,O75503,P17655,O15294,P55212,O76003,O14727,Q9BU89,Q86UY6,Q5TDH0
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
65,96,131,101,191,182,374,254,17,19,258,403,82,230,52,325,200,429
|
2647,52,403,1481,1255,19,101,1609,230,254,1256,589,1967,2661,3106,2302,668,191,1377,258,2305,2984,1502,1387,2210,96,2798,1997,1511,604,82,3053,1774,374,1524,2124,2676,992,1090,17,131,429,1898,623,931,200,2148,1203,65,1812,1686,1928,1327,2045,791,506,325,182,709,2460,2276,1706,2063,2705,1938,1345,1036,2474,2176
|
-0.7218933461099717,2.2705599514252803,0.8213525930752211,0.021154959123965873,0.1493999725419618,3.502094791440086,1.657680089871788,-0.04371782774137989,1.1661121430364376,1.1096416031090883,0.1493999725419618,0.6434302553162722,-0.24143086817602652,-0.7218933461099717,-1.6159672087429346,-0.4439584005973705,0.5832629155020134,1.277907963516101,0.08552503374798644,1.1096416031090883,-0.4439584005973705,-1.2317465192005141,0.021154959123965873,0.08552503374798644,-0.37590010541019514,1.7105328972774696,-0.8644153121428026,-0.24143086817602652,0.021154959123965873,0.6434302553162722,1.815231903298355,-1.3833236694797724,-0.10910107725747438,0.8798200308586908,0.021154959123965873,-0.30839382957997863,-0.7218933461099717,0.3381272349672459,0.2756939090187885,3.5863493747714164,1.4970570622608441,0.8213525930752211,-0.17500271918170665,0.6434302553162722,0.40009409100938204,1.277907963516101,-0.30839382957997863,0.21278718307129618,2.020717946656322,-0.10910107725747438,-0.04371782774137989,-0.17500271918170665,0.1493999725419618,-0.24143086817602652,0.5226553678023891,0.7624690661744893,0.9955294106635983,1.3332432815151989,0.5832629155020134,-0.5125776294717194,-0.37590010541019514,-0.04371782774137989,-0.24143086817602652,-0.7218933461099717,-0.17500271918170665,0.1493999725419618,0.3381272349672459,-0.5125776294717194,-0.30839382957997863
| 3,216
|
Hydrolase activity acting on glycosyl bonds
| 12
| 31
| 2.721126
| 0.006506
|
O60502,Q9NUJ1,P29372,Q86W56,P04062,Q9BQ69,O75503,Q6SZW1,P33908,P16278,P54802,Q9BTY2
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
34,307,312,385,135,220,19,291,81,88,235,162
|
1730,34,19,135,1369,363,2488,2662,830,2407,88,2955,1623,534,312,81,1385,235,1881,2806,2013,2611,291,385,220,162,3153,307,1032,1038,874
|
-0.10910107725747438,2.8408760799008674,3.502094791440086,1.4428130982976093,0.08552503374798644,0.8798200308586908,-0.5817669225092277,-0.7218933461099717,0.4616012571920667,-0.5125776294717194,1.7630487741502214,-1.1569763978106686,-0.04371782774137989,0.7031636084840797,0.9955294106635983,1.815231903298355,0.08552503374798644,1.1661121430364376,-0.17500271918170665,-0.8644153121428026,-0.24143086817602652,-0.6515356333511229,1.0527824505275314,0.8798200308586908,1.222199240405792,1.3882100669604411,-1.9365664874383406,1.0527824505275314,0.3381272349672459,0.3381272349672459,0.4616012571920667
| 3,216
|
Receptor
| 8
| 33
| 2.715608
| 0.006615
|
Q9NS69,P13591,P24390,Q8WTV0,Q92692,Q14739,P11474,P30825
|
Functions
|
Protein Atlas Molecular function
|
protein_atlas_molecular_function
|
0,156,3,297,180,16,57,208
|
1478,1246,1741,2660,1370,3142,1852,1746,2572,1974,828,57,286,156,1375,3,976,208,1071,3029,759,16,2243,765,297,180,1554,3170,0,2470,3203,1476,2076
|
0.021154959123965873,0.1493999725419618,-0.10910107725747438,-0.7218933461099717,0.08552503374798644,-1.85525960192129,-0.17500271918170665,-0.10910107725747438,-0.6515356333511229,-0.24143086817602652,0.4616012571920667,2.2211954204950515,1.0527824505275314,1.3882100669604411,0.08552503374798644,6.273729161291968,0.3381272349672459,1.222199240405792,0.2756939090187885,-1.307191595712573,0.5226553678023891,3.711122412271352,-0.37590010541019514,0.5226553678023891,1.0527824505275314,1.3332432815151989,0.021154959123965873,-2.101583678206865,8.262121890752995,-0.5125776294717194,-3.355013459755706,0.08552503374798644,-0.24143086817602652
| 3,216
|
Glycosaminoglycan metabolism
| 7
| 11
| 2.693181
| 0.007077
|
P06865,O43505,O95340,Q8TB61,P16278,P54802,Q96L58
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
363,93,190,269,88,235,161
|
966,93,190,363,2488,1495,88,235,269,161,454
|
0.3381272349672459,1.7105328972774696,1.277907963516101,0.8798200308586908,-0.5817669225092277,0.021154959123965873,1.7630487741502214,1.1661121430364376,1.1096416031090883,1.3882100669604411,0.8213525930752211
| 3,216
|
Organic hydroxy compound biosynthetic process
| 8
| 53
| 2.689091
| 0.007165
|
P04062,Q14739,Q15392,Q92551,Q15125,P48449,Q9UKG1,P37268
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
135,16,17,123,22,23,166,29
|
185,2560,1352,964,876,877,3017,885,1961,2192,135,889,3090,1063,2663,896,2883,1161,3023,2097,1268,2203,1384,29,1635,23,2219,2002,2847,1180,845,1410,685,2511,16,22,764,17,1092,769,1190,123,1438,1561,1444,790,1021,1228,2068,2913,166,358,654
|
1.277907963516101,-0.6515356333511229,0.08552503374798644,0.3381272349672459,0.40009409100938204,0.40009409100938204,-1.307191595712573,0.40009409100938204,-0.24143086817602652,-0.37590010541019514,1.4428130982976093,0.40009409100938204,-1.5376986032329918,0.2756939090187885,-0.7218933461099717,0.40009409100938204,-1.009414400019985,0.21278718307129618,-1.307191595712573,-0.30839382957997863,0.1493999725419618,-0.37590010541019514,0.08552503374798644,2.9774643320795486,-0.04371782774137989,3.41696171884832,-0.37590010541019514,-0.24143086817602652,-0.9365999560555965,0.21278718307129618,0.4616012571920667,0.08552503374798644,0.5832629155020134,-0.5817669225092277,3.711122412271352,3.459639186376742,0.5226553678023891,3.5863493747714164,0.2756939090187885,0.5226553678023891,0.21278718307129618,1.550946556196765,0.08552503374798644,0.021154959123965873,0.08552503374798644,0.5226553678023891,0.3381272349672459,0.21278718307129618,-0.24143086817602652,-1.009414400019985,1.3882100669604411,0.9378771015302817,0.6434302553162722
| 3,216
|
Disproportionate short stature
| 10
| 22
| 2.673915
| 0.007497
|
O15228,Q9UHX1,Q32P28,Q96HY6,Q14739,Q15392,Q15125,P10644,P16278,O75718
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
658,516,618,181,16,17,22,469,88,207
|
1134,658,1845,207,469,88,2092,1991,1507,2852,16,688,22,17,618,1419,2148,181,2271,2778,2068,516
|
0.21278718307129618,0.5832629155020134,-0.17500271918170665,1.222199240405792,0.7624690661744893,1.7630487741502214,-0.30839382957997863,-0.24143086817602652,0.021154959123965873,-0.9365999560555965,3.711122412271352,0.5832629155020134,3.459639186376742,3.5863493747714164,0.6434302553162722,0.08552503374798644,-0.30839382957997863,1.3332432815151989,-0.37590010541019514,-0.7928498829766004,-0.24143086817602652,0.7624690661744893
| 3,216
|
Protein dephosphorylation
| 25
| 75
| 2.659449
| 0.007827
|
Q13464,O00743,P04062,Q69YH5,Q9H2U2,P54098,Q06124,P18433,O60346,P49593,Q13555,Q99504,P63151,P62140,P62136,A6NDG6,P60510,Q16537,Q13614,Q86XL3,Q99956,Q8TF05,Q9ULE6,P16333,Q96GX5
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
484,252,135,141,571,48,289,172,404,62,316,70,421,420,419,185,418,345,210,90,245,243,106,118,273
|
185,252,579,878,404,2186,2187,135,1153,2196,2921,1974,2304,118,1858,172,2094,2096,833,743,1987,2412,1991,2211,62,2320,1392,2218,48,418,419,420,3094,1774,421,2119,1402,3130,1778,289,756,1885,484,1529,316,210,2516,2437,1670,345,545,771,141,1302,90,1314,2895,243,1206,1911,2625,1108,273,2694,1560,70,245,2533,1117,571,1119,1460,106,1037,873
|
1.277907963516101,1.1096416031090883,0.6434302553162722,0.40009409100938204,0.8213525930752211,-0.37590010541019514,-0.37590010541019514,1.4428130982976093,0.21278718307129618,-0.37590010541019514,-1.0828695011676135,-0.24143086817602652,-0.4439584005973705,1.550946556196765,-0.17500271918170665,1.3332432815151989,-0.30839382957997863,-0.30839382957997863,0.4616012571920667,0.5226553678023891,-0.24143086817602652,-0.5125776294717194,-0.24143086817602652,-0.37590010541019514,2.1215677563097355,-0.4439584005973705,0.08552503374798644,-0.37590010541019514,2.3684078704596625,0.8213525930752211,0.8213525930752211,0.8213525930752211,-1.5376986032329918,-0.10910107725747438,0.8213525930752211,-0.30839382957997863,0.08552503374798644,-1.7747337369891967,-0.10910107725747438,1.0527824505275314,0.5226553678023891,-0.17500271918170665,0.7624690661744893,0.021154959123965873,0.9955294106635983,1.222199240405792,-0.5817669225092277,-0.5125776294717194,-0.04371782774137989,0.9378771015302817,0.7031636084840797,0.5226553678023891,1.4428130982976093,0.1493999725419618,1.7630487741502214,0.1493999725419618,-1.009414400019985,1.1661121430364376,0.21278718307129618,-0.17500271918170665,-0.6515356333511229,0.2756939090187885,1.1096416031090883,-0.7218933461099717,0.021154959123965873,1.9698254903525632,1.1661121430364376,-0.5817669225092277,0.2756939090187885,0.7031636084840797,0.2756939090187885,0.08552503374798644,1.657680089871788,0.3381272349672459,0.4616012571920667
| 3,216
|
Alzheimers disease and mirna effects
| 28
| 86
| 2.632963
| 0.008464
|
Q07866,P55036,Q00535,P25787,P62195,P55210,O00213,P17655,P28070,O95197,Q9BUF5,Q9H0B6,P19784,O14727,P49720,P60900,P49721,P28072,P45880,Q13885,Q8NE86,P21796,Q9NQC3,P12235,O43242,P43686,P25789,O15111
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
482,480,609,366,606,604,250,258,136,25,445,305,532,52,414,539,64,193,69,687,626,77,224,334,463,474,595,580
|
250,816,1726,2479,1947,52,3015,580,463,25,1740,739,3019,2659,1154,1492,1155,2921,892,334,1747,1375,832,258,1064,1753,532,1496,77,2095,366,1068,595,1861,136,193,898,1629,1985,1990,1864,1169,2411,1991,2210,474,69,1639,1995,414,64,2320,2732,480,604,539,2423,606,908,1402,1178,609,1181,683,482,756,1184,2234,1659,2126,687,2130,1299,626,1441,1559,1813,1328,1692,1021,445,305,224,1238,1346,1039
|
1.1096416031090883,0.4616012571920667,-0.10910107725747438,-0.5817669225092277,-0.24143086817602652,2.2705599514252803,-1.307191595712573,0.6434302553162722,0.7624690661744893,3.111810995117898,-0.10910107725747438,0.5226553678023891,-1.307191595712573,-0.7218933461099717,0.21278718307129618,0.021154959123965873,0.21278718307129618,-1.0828695011676135,0.40009409100938204,0.9378771015302817,-0.10910107725747438,0.08552503374798644,0.4616012571920667,1.1096416031090883,0.2756939090187885,-0.10910107725747438,0.7031636084840797,0.021154959123965873,1.8670863906456077,-0.30839382957997863,0.8798200308586908,0.2756939090187885,0.6434302553162722,-0.17500271918170665,1.4428130982976093,1.277907963516101,0.40009409100938204,-0.04371782774137989,-0.24143086817602652,-0.24143086817602652,-0.17500271918170665,0.21278718307129618,-0.5125776294717194,-0.24143086817602652,-0.37590010541019514,0.7624690661744893,1.9698254903525632,-0.04371782774137989,-0.24143086817602652,0.8213525930752211,2.020717946656322,-0.4439584005973705,-0.7928498829766004,0.7624690661744893,0.6434302553162722,0.7031636084840797,-0.5125776294717194,0.6434302553162722,0.40009409100938204,0.08552503374798644,0.21278718307129618,0.6434302553162722,0.21278718307129618,0.5832629155020134,0.7624690661744893,0.5226553678023891,0.21278718307129618,-0.37590010541019514,-0.04371782774137989,-0.30839382957997863,0.5832629155020134,-0.30839382957997863,0.1493999725419618,0.6434302553162722,0.08552503374798644,0.021154959123965873,-0.10910107725747438,0.1493999725419618,-0.04371782774137989,0.3381272349672459,0.8213525930752211,1.0527824505275314,1.222199240405792,0.21278718307129618,0.1493999725419618,0.3381272349672459
| 3,216
|
Golgi apparatus
| 27
| 142
| 2.626857
| 0.008618
|
Q96JB2,P24390,P50897,Q93050,P07948,P50542,Q9H4A6,O14976,O95456,Q9HB40,Q86YR5,O15027,O14727,Q92896,O15260,Q9UJY4,Q9P000,P33908,P16278,Q6IAA8,Q6UWP2,Q13190,Q9HD45,P18858,Q9BQA1,Q5T6V5,Q08378
|
Localization
|
Protein Atlas Subcellular
|
protein_atlas_subcellular_location_all
|
133,3,130,12,256,137,183,283,285,47,177,169,52,65,186,87,226,81,88,211,214,102,116,232,124,122,120
|
725,1725,1602,962,578,52,283,169,1353,186,818,1249,731,1356,659,1731,1732,1484,528,1845,587,1738,3105,1256,285,1368,3126,256,740,1974,2088,286,3198,88,232,1161,3,2307,1627,2581,81,597,1386,2314,1632,2987,1993,1505,1507,1076,137,2417,1872,130,1078,985,2992,1079,2000,2002,3093,1650,2335,1181,3130,120,2607,374,2338,914,102,1087,1088,1663,2017,992,3035,122,1896,1193,211,1898,999,926,2022,214,2355,1541,383,2253,1425,1904,177,2755,2142,933,1428,779,554,2860,628,858,65,1554,12,1210,704,1919,133,1560,1444,2905,2044,124,796,639,945,1221,1700,1223,183,948,2060,1458,799,47,1459,116,952,1707,2379,226,719,2705,1715,1035,87,2644,1241,1720,2389,1840
|
0.5226553678023891,-0.10910107725747438,-0.04371782774137989,0.3381272349672459,0.6434302553162722,2.2705599514252803,1.0527824505275314,1.3332432815151989,0.08552503374798644,1.277907963516101,0.4616012571920667,0.1493999725419618,0.5226553678023891,0.08552503374798644,0.5832629155020134,-0.10910107725747438,-0.10910107725747438,0.021154959123965873,0.7031636084840797,-0.17500271918170665,0.6434302553162722,-0.10910107725747438,-1.6159672087429346,0.1493999725419618,1.0527824505275314,0.08552503374798644,-1.7747337369891967,1.1096416031090883,0.5226553678023891,-0.24143086817602652,-0.30839382957997863,1.0527824505275314,-2.7060722887314697,1.7630487741502214,1.1661121430364376,0.21278718307129618,6.273729161291968,-0.4439584005973705,-0.04371782774137989,-0.6515356333511229,1.815231903298355,0.6434302553162722,0.08552503374798644,-0.4439584005973705,-0.04371782774137989,-1.2317465192005141,-0.24143086817602652,0.021154959123965873,0.021154959123965873,0.2756939090187885,1.4428130982976093,-0.5125776294717194,-0.17500271918170665,1.4970570622608441,0.2756939090187885,0.3381272349672459,-1.2317465192005141,0.2756939090187885,-0.24143086817602652,-0.24143086817602652,-1.5376986032329918,-0.04371782774137989,-0.4439584005973705,0.21278718307129618,-1.7747337369891967,1.550946556196765,-0.6515356333511229,0.8798200308586908,-0.4439584005973705,0.40009409100938204,1.657680089871788,0.2756939090187885,0.2756939090187885,-0.04371782774137989,-0.24143086817602652,0.3381272349672459,-1.307191595712573,1.550946556196765,-0.17500271918170665,0.21278718307129618,1.222199240405792,-0.17500271918170665,0.3381272349672459,0.40009409100938204,-0.24143086817602652,1.222199240405792,-0.4439584005973705,0.021154959123965873,0.8798200308586908,-0.37590010541019514,0.08552503374798644,-0.17500271918170665,1.3332432815151989,-0.7928498829766004,-0.30839382957997863,0.40009409100938204,0.08552503374798644,0.5226553678023891,0.7031636084840797,-0.9365999560555965,0.6434302553162722,0.4616012571920667,2.020717946656322,0.021154959123965873,4.49741358097412,0.21278718307129618,0.5832629155020134,-0.17500271918170665,1.4970570622608441,0.021154959123965873,0.08552503374798644,-1.009414400019985,-0.24143086817602652,1.550946556196765,0.5226553678023891,0.6434302553162722,0.40009409100938204,0.21278718307129618,-0.04371782774137989,0.21278718307129618,1.3332432815151989,0.40009409100938204,-0.24143086817602652,0.08552503374798644,0.5226553678023891,2.4168980616095,0.08552503374798644,1.6044860903155633,0.40009409100938204,-0.04371782774137989,-0.4439584005973705,1.222199240405792,0.5832629155020134,-0.7218933461099717,-0.04371782774137989,0.3381272349672459,1.815231903298355,-0.6515356333511229,0.21278718307129618,-0.04371782774137989,-0.4439584005973705,-0.10910107725747438
| 3,216
|
Alzheimers disease
| 28
| 84
| 2.591791
| 0.009548
|
Q07866,P55036,Q00535,P25787,P62195,P55210,O00213,P17655,P28070,O95197,Q9BUF5,Q9H0B6,P19784,O14727,P49720,P60900,P49721,P28072,P45880,Q13885,Q8NE86,P21796,Q9NQC3,P12235,O43242,P43686,P25789,O15111
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
482,480,609,366,606,604,250,258,136,25,445,305,532,52,414,539,64,193,69,687,626,77,224,334,463,474,595,580
|
250,816,1726,2479,1947,52,3015,580,463,25,1740,739,3019,2659,1154,1492,1155,2921,892,334,1747,1375,832,258,1064,1753,532,1496,77,2095,366,1068,595,1861,136,193,898,1629,1985,1990,1864,1169,2411,1991,2210,474,69,1639,1995,414,64,2320,2732,480,604,539,2423,606,908,1402,1178,609,1181,683,482,756,1184,2234,1659,2126,687,2130,1299,626,1813,1328,1692,1021,445,305,224,1238,1346,1039
|
1.1096416031090883,0.4616012571920667,-0.10910107725747438,-0.5817669225092277,-0.24143086817602652,2.2705599514252803,-1.307191595712573,0.6434302553162722,0.7624690661744893,3.111810995117898,-0.10910107725747438,0.5226553678023891,-1.307191595712573,-0.7218933461099717,0.21278718307129618,0.021154959123965873,0.21278718307129618,-1.0828695011676135,0.40009409100938204,0.9378771015302817,-0.10910107725747438,0.08552503374798644,0.4616012571920667,1.1096416031090883,0.2756939090187885,-0.10910107725747438,0.7031636084840797,0.021154959123965873,1.8670863906456077,-0.30839382957997863,0.8798200308586908,0.2756939090187885,0.6434302553162722,-0.17500271918170665,1.4428130982976093,1.277907963516101,0.40009409100938204,-0.04371782774137989,-0.24143086817602652,-0.24143086817602652,-0.17500271918170665,0.21278718307129618,-0.5125776294717194,-0.24143086817602652,-0.37590010541019514,0.7624690661744893,1.9698254903525632,-0.04371782774137989,-0.24143086817602652,0.8213525930752211,2.020717946656322,-0.4439584005973705,-0.7928498829766004,0.7624690661744893,0.6434302553162722,0.7031636084840797,-0.5125776294717194,0.6434302553162722,0.40009409100938204,0.08552503374798644,0.21278718307129618,0.6434302553162722,0.21278718307129618,0.5832629155020134,0.7624690661744893,0.5226553678023891,0.21278718307129618,-0.37590010541019514,-0.04371782774137989,-0.30839382957997863,0.5832629155020134,-0.30839382957997863,0.1493999725419618,0.6434302553162722,-0.10910107725747438,0.1493999725419618,-0.04371782774137989,0.3381272349672459,0.8213525930752211,1.0527824505275314,1.222199240405792,0.21278718307129618,0.1493999725419618,0.3381272349672459
| 3,216
|
Hexosyltransferase activity
| 11
| 31
| 2.584756
| 0.009745
|
P06865,O43505,Q13126,Q86SF2,Q10471,P04062,Q9H488,O15294,Q6ZXV5,Q2TAA5,Q96L58
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
363,93,8,383,374,135,50,403,292,89,161
|
1351,403,93,1048,1843,1844,135,2299,1490,1744,363,2488,669,407,1385,1638,1287,2806,374,8,89,292,1902,383,2526,2623,161,3139,50,2911,2950
|
0.08552503374798644,0.8213525930752211,1.7105328972774696,0.2756939090187885,-0.17500271918170665,-0.17500271918170665,1.4428130982976093,-0.4439584005973705,0.021154959123965873,-0.10910107725747438,0.8798200308586908,-0.5817669225092277,0.5832629155020134,0.8213525930752211,0.08552503374798644,-0.04371782774137989,0.1493999725419618,-0.8644153121428026,0.8798200308586908,4.755586566332446,1.7630487741502214,1.0527824505275314,-0.17500271918170665,0.8798200308586908,-0.5817669225092277,-0.6515356333511229,1.3882100669604411,-1.7747337369891967,2.3196296243830314,-1.009414400019985,-1.0828695011676135
| 3,216
|
Serine protease
| 11
| 26
| 2.57871
| 0.009917
|
P42785,Q9H3G5,P48147,Q15365,Q92945,P13798,Q9HB40,P10619,Q96I24,Q15366,O14773
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
4,5,475,377,558,530,47,592,443,239,117
|
1136,117,592,530,1069,2841,4,475,2322,2589,2007,1407,377,239,697,3038,2257,1914,558,935,443,5,47,1937,1470,2874
|
0.21278718307129618,1.550946556196765,0.6434302553162722,0.7031636084840797,0.2756939090187885,-0.9365999560555965,6.273729161291968,0.7624690661744893,-0.4439584005973705,-0.6515356333511229,-0.24143086817602652,0.08552503374798644,0.8798200308586908,1.1661121430364376,0.5832629155020134,-1.307191595712573,-0.37590010541019514,-0.17500271918170665,0.7031636084840797,0.40009409100938204,0.8213525930752211,5.809318295160335,2.4168980616095,-0.17500271918170665,0.08552503374798644,-0.9365999560555965
| 3,216
|
Glycoprotein biosynthetic process
| 16
| 42
| 2.568929
| 0.010201
|
Q96JB2,O60502,O43505,P35610,Q9UHD1,Q9H4A6,Q86SF2,Q10471,O60701,Q96L58,Q9H488,Q6ZXV5,P33908,Q2TAA5,Q86YN1,Q99805
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
133,34,93,129,454,183,383,374,284,161,50,292,81,89,433,63
|
1351,1352,403,93,34,1048,284,1843,1844,2980,466,2299,1490,81,1864,129,1868,1638,3108,1287,684,2607,374,2013,2679,89,292,1902,383,433,2623,133,161,63,3139,2769,50,183,2869,2911,454,2950
|
0.08552503374798644,0.08552503374798644,0.8213525930752211,1.7105328972774696,2.8408760799008674,0.2756939090187885,1.0527824505275314,-0.17500271918170665,-0.17500271918170665,-1.2317465192005141,0.7624690661744893,-0.4439584005973705,0.021154959123965873,1.815231903298355,-0.17500271918170665,1.4970570622608441,-0.17500271918170665,-0.04371782774137989,-1.6159672087429346,0.1493999725419618,0.5832629155020134,-0.6515356333511229,0.8798200308586908,-0.24143086817602652,-0.7218933461099717,1.7630487741502214,1.0527824505275314,-0.17500271918170665,0.8798200308586908,0.8213525930752211,-0.6515356333511229,1.4970570622608441,1.3882100669604411,2.0712974525073755,-1.7747337369891967,-0.7928498829766004,2.3196296243830314,1.3332432815151989,-0.9365999560555965,-1.009414400019985,0.8213525930752211,-1.0828695011676135
| 3,216
|
Glycosyltransferase activity
| 14
| 45
| 2.566077
| 0.010286
|
P06865,O43505,Q13126,Q86SF2,Q10471,Q9H974,P04062,P43490,Q9H488,O15294,Q6ZXV5,P13807,Q2TAA5,Q96L58
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
363,93,8,383,374,115,135,287,50,403,292,407,89,161
|
1351,403,93,1048,1843,1844,2193,2194,135,2299,1490,1744,363,2488,1493,2302,973,669,407,1385,287,1638,1287,2806,1183,374,8,2682,89,292,1541,1902,383,2526,2623,1438,161,3139,2769,50,115,2911,1034,519,2950
|
0.08552503374798644,0.8213525930752211,1.7105328972774696,0.2756939090187885,-0.17500271918170665,-0.17500271918170665,-0.37590010541019514,-0.37590010541019514,1.4428130982976093,-0.4439584005973705,0.021154959123965873,-0.10910107725747438,0.8798200308586908,-0.5817669225092277,0.021154959123965873,-0.4439584005973705,0.3381272349672459,0.5832629155020134,0.8213525930752211,0.08552503374798644,1.0527824505275314,-0.04371782774137989,0.1493999725419618,-0.8644153121428026,0.21278718307129618,0.8798200308586908,4.755586566332446,-0.7218933461099717,1.7630487741502214,1.0527824505275314,0.021154959123965873,-0.17500271918170665,0.8798200308586908,-0.5817669225092277,-0.6515356333511229,0.08552503374798644,1.3882100669604411,-1.7747337369891967,-0.7928498829766004,2.3196296243830314,1.6044860903155633,-1.009414400019985,0.3381272349672459,0.7624690661744893,-1.0828695011676135
| 3,216
|
Vacuolar membrane
| 20
| 104
| 2.544196
| 0.010953
|
Q9BTU6,P42785,Q05639,Q93050,P04062,Q8TDB6,O75503,P07948,Q9P253,Q9H0B6,Q9BZH6,Q8WTV0,Q9Y487,O15260,Q8NF37,Q13614,Q8IV08,Q6IAA8,P63096,Q9H269
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
274,4,373,12,135,18,19,256,33,305,448,297,45,186,217,210,91,211,236,393
|
1602,2562,186,2077,2289,1360,2717,2653,19,1738,2081,2297,135,1490,3106,827,256,2721,1614,2196,890,3020,2662,592,2405,828,974,1979,1754,1987,1990,3052,1272,1868,1991,4,1993,2418,2321,1279,1642,906,3093,907,2501,2005,842,1650,909,2118,236,3095,2506,373,542,2337,2338,210,3185,211,91,553,2622,2363,217,2030,18,297,2759,3008,12,1918,1811,1439,2627,1441,2040,1561,1815,791,274,2373,448,305,2374,393,1453,1458,450,1459,2466,646,1825,33,1466,1235,2468,1125,809,2871,2915,959,520,45
|
-0.04371782774137989,-0.6515356333511229,1.277907963516101,-0.30839382957997863,-0.4439584005973705,0.08552503374798644,-0.7928498829766004,-0.7218933461099717,3.502094791440086,-0.10910107725747438,-0.30839382957997863,-0.4439584005973705,1.4428130982976093,0.021154959123965873,-1.6159672087429346,0.4616012571920667,1.1096416031090883,-0.7928498829766004,-0.04371782774137989,-0.37590010541019514,0.40009409100938204,-1.307191595712573,-0.7218933461099717,0.6434302553162722,-0.5125776294717194,0.4616012571920667,0.3381272349672459,-0.24143086817602652,-0.10910107725747438,-0.24143086817602652,-0.24143086817602652,-1.3833236694797724,0.1493999725419618,-0.17500271918170665,-0.24143086817602652,6.273729161291968,-0.24143086817602652,-0.5125776294717194,-0.4439584005973705,0.1493999725419618,-0.04371782774137989,0.40009409100938204,-1.5376986032329918,0.40009409100938204,-0.5817669225092277,-0.24143086817602652,0.4616012571920667,-0.04371782774137989,0.40009409100938204,-0.30839382957997863,1.1661121430364376,-1.5376986032329918,-0.5817669225092277,0.8798200308586908,0.7031636084840797,-0.4439584005973705,-0.4439584005973705,1.222199240405792,-2.441679403735763,1.222199240405792,1.7630487741502214,0.7031636084840797,-0.6515356333511229,-0.4439584005973705,1.222199240405792,-0.24143086817602652,3.5863493747714164,1.0527824505275314,-0.7928498829766004,-1.2317465192005141,4.49741358097412,-0.17500271918170665,-0.10910107725747438,0.08552503374798644,-0.6515356333511229,0.08552503374798644,-0.24143086817602652,0.021154959123965873,-0.10910107725747438,0.5226553678023891,1.1096416031090883,-0.4439584005973705,0.8213525930752211,1.0527824505275314,-0.4439584005973705,0.8798200308586908,0.08552503374798644,0.08552503374798644,0.8213525930752211,0.08552503374798644,-0.5125776294717194,0.6434302553162722,-0.10910107725747438,2.886659085145426,0.08552503374798644,0.21278718307129618,-0.5125776294717194,0.2756939090187885,0.5226553678023891,-0.9365999560555965,-1.009414400019985,0.40009409100938204,0.7624690661744893,2.4651035119965186
| 3,216
|
Trna methylation
| 15
| 20
| 2.537578
| 0.011162
|
Q9UBP6,Q6YHU6,Q99714,Q7Z2T5,Q9UI30,Q96BT7,O75648,Q96FX7,Q9UET6,O60294,Q9NNW5,Q9BV44,Q7Z4G4,Q08J23,Q9Y2Z2
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
647,1096,1021,549,282,146,253,442,807,584,1120,568,696,1085,652
|
584,253,1081,1085,1886,1096,2023,549,696,1808,146,442,1021,568,1697,1120,647,807,282,652
|
0.6434302553162722,1.1096416031090883,0.2756939090187885,0.2756939090187885,-0.17500271918170665,0.2756939090187885,-0.24143086817602652,0.7031636084840797,0.5832629155020134,-0.10910107725747438,1.4428130982976093,0.8213525930752211,0.3381272349672459,0.7031636084840797,-0.04371782774137989,0.2756939090187885,0.6434302553162722,0.5226553678023891,1.1096416031090883,0.6434302553162722
| 3,216
|
Bone development
| 10
| 28
| 2.525322
| 0.011559
|
Q92896,P13797,Q9Y6W5,Q12948,O75844,P12931,O95340,Q06124,Q15125,Q15904
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
65,95,249,339,101,191,190,289,22,379
|
883,101,190,2658,1612,3106,2721,191,95,896,2092,1266,1765,1997,1648,289,339,22,1790,379,2518,618,3040,857,65,455,1597,249
|
0.40009409100938204,1.657680089871788,1.277907963516101,-0.7218933461099717,-0.04371782774137989,-1.6159672087429346,-0.7928498829766004,1.277907963516101,1.7105328972774696,0.40009409100938204,-0.30839382957997863,0.1493999725419618,-0.10910107725747438,-0.24143086817602652,-0.04371782774137989,1.0527824505275314,0.9378771015302817,3.459639186376742,-0.10910107725747438,0.8798200308586908,-0.5817669225092277,0.6434302553162722,-1.307191595712573,0.4616012571920667,2.020717946656322,0.8213525930752211,0.021154959123965873,1.1661121430364376
| 3,216
|
Coxa vara
| 6
| 13
| 2.504687
| 0.012256
|
Q96HY6,Q9Y487,P50542,Q9NUQ7,Q5F1R6,O75718
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
181,45,137,513,381,207
|
1845,207,1850,1266,137,841,381,560,181,2043,513,1597,45
|
-0.17500271918170665,1.222199240405792,-0.17500271918170665,0.1493999725419618,1.4428130982976093,0.4616012571920667,0.8798200308586908,0.7031636084840797,1.3332432815151989,-0.24143086817602652,0.7624690661744893,0.021154959123965873,2.4651035119965186
| 3,216
|
Terpenoid metabolic process
| 7
| 15
| 2.481549
| 0.013081
|
Q9HBH5,Q8NBN7,Q9HB40,P48449,P29375,O60678,P37268
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
450,296,47,23,472,330,29
|
330,829,2663,2199,472,29,23,1514,1180,1095,296,1549,47,450,653
|
0.9378771015302817,0.4616012571920667,-0.7218933461099717,-0.37590010541019514,0.7624690661744893,2.9774643320795486,3.41696171884832,0.021154959123965873,0.21278718307129618,0.2756939090187885,1.0527824505275314,0.021154959123965873,2.4168980616095,0.8213525930752211,0.6434302553162722
| 3,216
|
Cation transmembrane transporter activity
| 11
| 61
| 2.469388
| 0.013534
|
P23634,Q70HW3,Q9HD20,O75964,Q93050,Q9Y487,O43772,P48047,Q13423,Q9UDW1,P30825
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
36,7,42,189,12,45,15,79,83,125,208
|
15,526,734,189,1055,2399,1743,1613,2659,3161,3106,2721,1614,1970,2404,334,1373,2489,832,1380,1621,974,1979,36,2093,2793,208,676,3051,3052,1272,1506,79,1875,1644,842,2960,1286,609,83,765,2815,212,7,1102,626,1554,12,303,3209,941,797,1025,2277,1818,42,125,1235,958,45,656
|
4.152948119514853,0.7031636084840797,0.5226553678023891,1.277907963516101,0.2756939090187885,-0.5125776294717194,-0.10910107725747438,-0.04371782774137989,-0.7218933461099717,-2.018669375001116,-1.6159672087429346,-0.7928498829766004,-0.04371782774137989,-0.24143086817602652,-0.5125776294717194,0.9378771015302817,0.08552503374798644,-0.5817669225092277,0.4616012571920667,0.08552503374798644,-0.04371782774137989,0.3381272349672459,-0.24143086817602652,2.7948357651419897,-0.30839382957997863,-0.8644153121428026,1.222199240405792,0.5832629155020134,-1.3833236694797724,-1.3833236694797724,0.1493999725419618,0.021154959123965873,1.8670863906456077,-0.17500271918170665,-0.04371782774137989,0.4616012571920667,-1.1569763978106686,0.1493999725419618,0.6434302553162722,1.815231903298355,0.5226553678023891,-0.8644153121428026,1.222199240405792,4.791807119309899,0.2756939090187885,0.6434302553162722,0.021154959123965873,4.49741358097412,1.0527824505275314,-4.255425597507842,0.40009409100938204,0.5226553678023891,0.3381272349672459,-0.37590010541019514,-0.10910107725747438,2.560673166001156,1.550946556196765,0.21278718307129618,0.40009409100938204,2.4651035119965186,0.6434302553162722
| 3,216
|
Glycosylation
| 15
| 39
| 2.427759
| 0.015192
|
Q96JB2,O60502,O43505,Q9UHD1,Q86SF2,Q10471,P04062,Q96L58,Q9H488,O75503,O15294,Q6ZXV5,P33908,Q2TAA5,Q86YN1
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
133,34,93,454,383,374,135,161,50,19,403,292,81,89,433
|
1351,403,93,34,1048,1843,1844,2980,19,466,135,2299,1490,81,1868,1638,3108,1287,684,2607,374,2013,2679,89,292,1902,383,433,2623,133,161,3139,2769,50,803,2911,454,1241,2950
|
0.08552503374798644,0.8213525930752211,1.7105328972774696,2.8408760799008674,0.2756939090187885,-0.17500271918170665,-0.17500271918170665,-1.2317465192005141,3.502094791440086,0.7624690661744893,1.4428130982976093,-0.4439584005973705,0.021154959123965873,1.815231903298355,-0.17500271918170665,-0.04371782774137989,-1.6159672087429346,0.1493999725419618,0.5832629155020134,-0.6515356333511229,0.8798200308586908,-0.24143086817602652,-0.7218933461099717,1.7630487741502214,1.0527824505275314,-0.17500271918170665,0.8798200308586908,0.8213525930752211,-0.6515356333511229,1.4970570622608441,1.3882100669604411,-1.7747337369891967,-0.7928498829766004,2.3196296243830314,0.5226553678023891,-1.009414400019985,0.8213525930752211,0.21278718307129618,-1.0828695011676135
| 3,216
|
Establishment of protein localization to membrane
| 15
| 76
| 2.417976
| 0.015607
|
Q9NS69,Q9BZG1,P09132,O60725,Q9UHB9,P43307,Q9HD20,Q9H4A6,Q15904,Q9UJY4,P46379,P50542,O15027,Q4J6C6,Q9Y276
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
0,134,364,187,453,157,42,183,379,87,109,137,169,61,456
|
1724,1602,169,1356,1359,1252,2834,187,823,1958,887,1965,1613,2400,1852,364,2921,2100,2102,1270,1503,899,1273,157,109,1993,2799,137,2321,750,2596,2115,841,1282,2960,1285,609,2335,847,2812,3058,1530,1787,379,61,995,2442,2138,2752,1542,2258,1430,2261,1807,559,1561,1929,134,865,1026,183,2060,42,1459,0,1461,1469,453,454,87,3047,456,1722,1042,2710,3014
|
-0.10910107725747438,-0.04371782774137989,1.3332432815151989,0.08552503374798644,0.08552503374798644,0.1493999725419618,-0.9365999560555965,1.277907963516101,0.4616012571920667,-0.24143086817602652,0.40009409100938204,-0.24143086817602652,-0.04371782774137989,-0.5125776294717194,-0.17500271918170665,0.8798200308586908,-1.0828695011676135,-0.30839382957997863,-0.30839382957997863,0.1493999725419618,0.021154959123965873,0.40009409100938204,0.1493999725419618,1.3882100669604411,1.6044860903155633,-0.24143086817602652,-0.8644153121428026,1.4428130982976093,-0.4439584005973705,0.5226553678023891,-0.6515356333511229,-0.30839382957997863,0.4616012571920667,0.1493999725419618,-1.1569763978106686,0.1493999725419618,0.6434302553162722,-0.4439584005973705,0.4616012571920667,-0.8644153121428026,-1.3833236694797724,0.021154959123965873,-0.10910107725747438,0.8798200308586908,2.1715325399779393,0.3381272349672459,-0.5125776294717194,-0.30839382957997863,-0.7928498829766004,0.021154959123965873,-0.37590010541019514,0.08552503374798644,-0.37590010541019514,-0.10910107725747438,0.7031636084840797,0.021154959123965873,-0.17500271918170665,1.4970570622608441,0.4616012571920667,0.3381272349672459,1.3332432815151989,-0.24143086817602652,2.560673166001156,0.08552503374798644,8.262121890752995,0.08552503374798644,0.08552503374798644,0.8213525930752211,0.8213525930752211,1.815231903298355,-1.307191595712573,0.8213525930752211,-0.04371782774137989,0.3381272349672459,-0.7218933461099717,-1.2317465192005141
| 3,216
|
Glycoprotein metabolic process
| 16
| 48
| 2.404694
| 0.016186
|
Q96JB2,O60502,O43505,P35610,Q9UHD1,Q9H4A6,Q86SF2,Q10471,O60701,Q96L58,Q9H488,Q6ZXV5,P33908,Q2TAA5,Q86YN1,Q99805
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
133,34,93,129,454,183,383,374,284,161,50,292,81,89,433,63
|
1351,1352,403,93,34,1048,284,1843,1844,2980,466,2299,1490,2789,81,1864,129,1868,1638,3108,1520,1287,684,2607,374,2013,2679,2611,89,292,1902,383,433,2623,133,161,790,63,2766,3139,945,2769,50,183,2869,2911,454,2950
|
0.08552503374798644,0.08552503374798644,0.8213525930752211,1.7105328972774696,2.8408760799008674,0.2756939090187885,1.0527824505275314,-0.17500271918170665,-0.17500271918170665,-1.2317465192005141,0.7624690661744893,-0.4439584005973705,0.021154959123965873,-0.8644153121428026,1.815231903298355,-0.17500271918170665,1.4970570622608441,-0.17500271918170665,-0.04371782774137989,-1.6159672087429346,0.021154959123965873,0.1493999725419618,0.5832629155020134,-0.6515356333511229,0.8798200308586908,-0.24143086817602652,-0.7218933461099717,-0.6515356333511229,1.7630487741502214,1.0527824505275314,-0.17500271918170665,0.8798200308586908,0.8213525930752211,-0.6515356333511229,1.4970570622608441,1.3882100669604411,0.5226553678023891,2.0712974525073755,-0.7928498829766004,-1.7747337369891967,0.40009409100938204,-0.7928498829766004,2.3196296243830314,1.3332432815151989,-0.9365999560555965,-1.009414400019985,0.8213525930752211,-1.0828695011676135
| 3,216
|
S-adenosyl-L-methionine-dependent methyltransferase [IPR029063]
| 20
| 47
| 2.401962
| 0.016307
|
Q9BV86,Q96BT7,Q96FX7,Q9BV44,Q8IZ69,Q7Z4G4,Q9HBK9,Q7Z2T5,O43709,P52788,Q7L2J0,Q86W50,P21964,Q96P11,Q14353,O60678,Q9UBP6,P19623,O43148,O60294
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
10,146,442,568,698,696,164,549,525,288,432,294,192,633,342,330,647,594,229,584
|
2394,229,2181,525,584,330,594,192,1981,2922,1860,2731,1995,288,1085,342,997,1420,927,432,1099,549,696,294,855,2938,698,2028,2029,1103,2032,146,2969,442,633,707,568,10,1697,164,2639,647,807,1342,2975,1592,1600
|
-0.5125776294717194,1.1661121430364376,-0.37590010541019514,0.7031636084840797,0.6434302553162722,0.9378771015302817,0.6434302553162722,1.277907963516101,-0.24143086817602652,-1.0828695011676135,-0.17500271918170665,-0.7928498829766004,-0.24143086817602652,1.0527824505275314,0.2756939090187885,0.9378771015302817,0.3381272349672459,0.08552503374798644,0.40009409100938204,0.8213525930752211,0.2756939090187885,0.7031636084840797,0.5832629155020134,1.0527824505275314,0.4616012571920667,-1.0828695011676135,0.5832629155020134,-0.24143086817602652,-0.24143086817602652,0.2756939090187885,-0.24143086817602652,1.4428130982976093,-1.1569763978106686,0.8213525930752211,0.6434302553162722,0.5832629155020134,0.7031636084840797,4.719203601847822,-0.04371782774137989,1.3882100669604411,-0.6515356333511229,0.6434302553162722,0.5226553678023891,0.1493999725419618,-1.1569763978106686,0.021154959123965873,0.021154959123965873
| 3,216
|
Aminoglycan metabolic process
| 6
| 11
| 2.400708
| 0.016363
|
O43505,Q12948,O60701,P16278,P54802,Q96L58
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
93,339,284,88,235,161
|
93,284,2297,363,2488,1495,88,235,2506,339,161
|
1.7105328972774696,1.0527824505275314,-0.4439584005973705,0.8798200308586908,-0.5817669225092277,0.021154959123965873,1.7630487741502214,1.1661121430364376,-0.5817669225092277,0.9378771015302817,1.3882100669604411
| 3,216
|
Anion transmembrane transport
| 11
| 37
| 2.396828
| 0.016538
|
Q96NB2,Q9H2D1,P12235,Q9UBX3,P45880,Q9UHG3,Q8TDW0,P21796,O43808,Q8TB61,P30825
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
303,1,334,515,69,11,628,77,526,269,208
|
526,2784,969,3086,1739,2659,2660,1614,334,1747,77,208,69,2217,2926,1875,1286,2230,2235,1530,765,2815,1102,269,628,303,797,1,2277,1818,1459,515,11,1589,1039,1722,656
|
0.7031636084840797,-0.8644153121428026,0.3381272349672459,-1.5376986032329918,-0.10910107725747438,-0.7218933461099717,-0.7218933461099717,-0.04371782774137989,0.9378771015302817,-0.10910107725747438,1.8670863906456077,1.222199240405792,1.9698254903525632,-0.37590010541019514,-1.0828695011676135,-0.17500271918170665,0.1493999725419618,-0.37590010541019514,-0.37590010541019514,0.021154959123965873,0.5226553678023891,-0.8644153121428026,0.2756939090187885,1.1096416031090883,0.6434302553162722,1.0527824505275314,0.5226553678023891,7.395141724241461,-0.37590010541019514,-0.10910107725747438,0.08552503374798644,0.7624690661744893,4.60906581420569,0.021154959123965873,0.3381272349672459,-0.04371782774137989,0.6434302553162722
| 3,216
|
Negative regulation of establishment of protein localization
| 13
| 26
| 2.383906
| 0.01713
|
Q16836,P17858,Q00535,Q9UHD1,Q9ULC3,Q08209,P40939,O95817,Q06124,Q99497,O75608,P21359,P49593
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
428,673,609,454,455,756,680,590,289,790,823,233,62
|
1726,1361,823,590,673,233,2309,2102,1269,680,1273,1275,2498,62,840,609,289,756,428,1190,790,1446,1459,454,455,1345
|
-0.10910107725747438,0.08552503374798644,0.4616012571920667,0.6434302553162722,0.5832629155020134,1.1661121430364376,-0.4439584005973705,-0.30839382957997863,0.1493999725419618,0.5832629155020134,0.1493999725419618,0.1493999725419618,-0.5817669225092277,2.1215677563097355,0.4616012571920667,0.6434302553162722,1.0527824505275314,0.5226553678023891,0.8213525930752211,0.21278718307129618,0.5226553678023891,0.08552503374798644,0.08552503374798644,0.8213525930752211,0.8213525930752211,0.1493999725419618
| 3,216
|
Amyloid precursor protein catabolic process
| 6
| 15
| 2.369116
| 0.017831
|
Q13464,Q15392,P07948,P27695,Q9NQC3,O95197
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
484,17,256,534,224,25
|
2186,25,256,534,2210,1076,1774,484,848,1529,1294,17,1689,705,224
|
-0.37590010541019514,3.111810995117898,1.1096416031090883,0.7031636084840797,-0.37590010541019514,0.2756939090187885,-0.10910107725747438,0.7624690661744893,0.4616012571920667,0.021154959123965873,0.1493999725419618,3.5863493747714164,-0.04371782774137989,0.5832629155020134,1.222199240405792
| 3,216
|
Amyloid precursor protein metabolic process
| 7
| 17
| 2.31541
| 0.02059
|
Q13464,P35610,Q15392,P07948,P27695,Q9NQC3,O95197
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
484,129,17,256,534,224,25
|
2186,25,256,534,129,2210,1076,1774,484,848,1529,1294,17,1689,705,224,2869
|
-0.37590010541019514,3.111810995117898,1.1096416031090883,0.7031636084840797,1.4970570622608441,-0.37590010541019514,0.2756939090187885,-0.10910107725747438,0.7624690661744893,0.4616012571920667,0.021154959123965873,0.1493999725419618,3.5863493747714164,-0.04371782774137989,0.5832629155020134,1.222199240405792,-0.9365999560555965
| 3,216
|
Sulfur compound biosynthetic process
| 16
| 42
| 2.301028
| 0.02139
|
Q15120,P50897,P35610,O43505,Q13126,O95340,O60701,Q9NUB1,Q8TB61,Q86W50,P25325,Q99735,Q8WUX2,Q96L58,Q9BV20,P48637
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
195,130,129,93,8,190,284,356,269,294,471,505,322,161,446,368
|
3085,966,93,1731,284,190,1739,1965,3088,2839,972,1372,1158,1374,1756,471,1759,2312,473,129,904,1508,368,130,2217,2219,3200,8,195,3096,1418,294,269,322,1105,161,1330,505,446,356,2829,1822
|
-1.5376986032329918,0.3381272349672459,1.7105328972774696,-0.10910107725747438,1.0527824505275314,1.277907963516101,-0.10910107725747438,-0.24143086817602652,-1.5376986032329918,-0.9365999560555965,0.3381272349672459,0.08552503374798644,0.21278718307129618,0.08552503374798644,-0.10910107725747438,0.7624690661744893,-0.10910107725747438,-0.4439584005973705,0.7624690661744893,1.4970570622608441,0.40009409100938204,0.021154959123965873,0.8798200308586908,1.4970570622608441,-0.37590010541019514,-0.37590010541019514,-2.8869049974604595,4.755586566332446,1.277907963516101,-1.5376986032329918,0.08552503374798644,1.0527824505275314,1.1096416031090883,0.9955294106635983,0.2756939090187885,1.3882100669604411,0.1493999725419618,0.7624690661744893,0.8213525930752211,0.9378771015302817,-0.8644153121428026,-0.10910107725747438
| 3,216
|
SLC superfamily of solute carriers
| 11
| 34
| 2.289979
| 0.022023
|
Q96NB2,Q9H2D1,P12235,Q9UBX3,Q70HW3,O43772,O43808,Q8TB61,Q9Y6M7,Q9Y6C9,P30825
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
303,1,334,515,7,15,526,269,656,655,208
|
15,526,969,1055,1739,2659,1614,334,1747,208,2217,2926,1875,1286,2230,765,1677,1899,7,1102,269,303,3209,941,797,1,1025,2277,1818,646,515,1589,655,656
|
4.152948119514853,0.7031636084840797,0.3381272349672459,0.2756939090187885,-0.10910107725747438,-0.7218933461099717,-0.04371782774137989,0.9378771015302817,-0.10910107725747438,1.222199240405792,-0.37590010541019514,-1.0828695011676135,-0.17500271918170665,0.1493999725419618,-0.37590010541019514,0.5226553678023891,-0.04371782774137989,-0.17500271918170665,4.791807119309899,0.2756939090187885,1.1096416031090883,1.0527824505275314,-4.255425597507842,0.40009409100938204,0.5226553678023891,7.395141724241461,0.3381272349672459,-0.37590010541019514,-0.10910107725747438,0.6434302553162722,0.7624690661744893,0.021154959123965873,0.6434302553162722,0.6434302553162722
| 3,216
|
AH/BAR domain superfamily [IPR027267]
| 6
| 14
| 2.283812
| 0.022383
|
Q9Y371,Q9Y5X1,Q9UKG1,Q68EM7,Q15642,Q9UQB8
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
520,80,166,198,27,31
|
1362,2992,485,27,198,942,166,1239,1126,1240,31,520,80,1131
|
0.08552503374798644,-1.2317465192005141,0.7624690661744893,3.022492044155325,1.277907963516101,0.40009409100938204,1.3882100669604411,0.21278718307129618,0.2756939090187885,0.21278718307129618,2.932187583429893,0.7624690661744893,1.8670863906456077,0.2756939090187885
| 3,216
|
Organic hydroxy compound metabolic process
| 16
| 108
| 2.282418
| 0.022465
|
P07858,P35610,P21964,Q8WTV0,Q8NBN7,A6NDG6,P04062,Q14739,Q15392,Q9NUB1,Q92551,Q15125,P48449,Q9UKG1,Q13614,P37268
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
154,129,192,297,296,185,135,16,17,356,123,22,23,166,210,29
|
185,2560,1352,964,876,877,659,2184,1843,3017,969,885,1608,1961,737,1851,2192,2194,135,1612,889,2084,154,468,3090,1063,829,2663,1374,2199,896,2576,2883,192,1161,3023,1163,2097,1268,2203,1630,1384,129,29,1635,901,23,1390,1391,1277,2419,1078,984,1514,2219,2002,2422,751,2847,1877,1522,2227,1882,1180,1883,845,1524,1410,685,2236,210,2511,16,22,764,17,1790,1092,769,1190,1095,3182,2894,296,1549,297,123,1438,1108,1561,1444,790,1021,2273,2050,2769,450,1228,2162,356,2068,1588,2913,166,1037,653,358,654
|
1.277907963516101,-0.6515356333511229,0.08552503374798644,0.3381272349672459,0.40009409100938204,0.40009409100938204,0.5832629155020134,-0.37590010541019514,-0.17500271918170665,-1.307191595712573,0.3381272349672459,0.40009409100938204,-0.04371782774137989,-0.24143086817602652,0.5226553678023891,-0.17500271918170665,-0.37590010541019514,-0.37590010541019514,1.4428130982976093,-0.04371782774137989,0.40009409100938204,-0.30839382957997863,1.3882100669604411,0.7624690661744893,-1.5376986032329918,0.2756939090187885,0.4616012571920667,-0.7218933461099717,0.08552503374798644,-0.37590010541019514,0.40009409100938204,-0.6515356333511229,-1.009414400019985,1.277907963516101,0.21278718307129618,-1.307191595712573,0.21278718307129618,-0.30839382957997863,0.1493999725419618,-0.37590010541019514,-0.04371782774137989,0.08552503374798644,1.4970570622608441,2.9774643320795486,-0.04371782774137989,0.40009409100938204,3.41696171884832,0.08552503374798644,0.08552503374798644,0.1493999725419618,-0.5125776294717194,0.2756939090187885,0.3381272349672459,0.021154959123965873,-0.37590010541019514,-0.24143086817602652,-0.5125776294717194,0.5226553678023891,-0.9365999560555965,-0.17500271918170665,0.021154959123965873,-0.37590010541019514,-0.17500271918170665,0.21278718307129618,-0.17500271918170665,0.4616012571920667,0.021154959123965873,0.08552503374798644,0.5832629155020134,-0.37590010541019514,1.222199240405792,-0.5817669225092277,3.711122412271352,3.459639186376742,0.5226553678023891,3.5863493747714164,-0.10910107725747438,0.2756939090187885,0.5226553678023891,0.21278718307129618,0.2756939090187885,-2.355356056585581,-1.009414400019985,1.0527824505275314,0.021154959123965873,1.0527824505275314,1.550946556196765,0.08552503374798644,0.2756939090187885,0.021154959123965873,0.08552503374798644,0.5226553678023891,0.3381272349672459,-0.37590010541019514,-0.24143086817602652,-0.7928498829766004,0.8213525930752211,0.21278718307129618,-0.30839382957997863,0.9378771015302817,-0.24143086817602652,0.021154959123965873,-1.009414400019985,1.3882100669604411,0.3381272349672459,0.6434302553162722,0.9378771015302817,0.6434302553162722
| 3,216
|
Regulation of hormone levels
| 26
| 67
| 2.281199
| 0.022537
|
Q16822,Q00536,P00367,P55809,P07948,Q92506,P07858,Q9HBH5,Q8NBN7,Q9HB40,Q06124,O95470,O00161,Q13555,Q16836,P17858,Q7Z7E8,O95340,Q8NE86,P40939,Q9BRT2,Q99497,Q9Y394,O60678,Q6UWP2,O75844
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
769,610,738,605,256,438,154,450,296,47,289,171,167,316,428,673,318,190,626,680,221,790,653,330,214,101
|
167,1601,1726,1480,1731,330,101,190,171,1739,738,2788,1743,154,256,1157,1375,1159,2199,896,673,1161,2884,1986,680,1767,3194,2111,1279,2926,605,1520,1522,610,289,756,1657,1407,1528,316,1790,769,428,1537,1418,1095,214,318,296,1313,626,1549,438,1807,1686,2764,2904,790,1021,221,47,450,2467,2068,1036,1240,653
|
1.3332432815151989,-0.04371782774137989,-0.10910107725747438,0.021154959123965873,-0.10910107725747438,0.9378771015302817,1.657680089871788,1.277907963516101,1.3332432815151989,-0.10910107725747438,0.5226553678023891,-0.8644153121428026,-0.10910107725747438,1.3882100669604411,1.1096416031090883,0.21278718307129618,0.08552503374798644,0.21278718307129618,-0.37590010541019514,0.40009409100938204,0.5832629155020134,0.21278718307129618,-1.009414400019985,-0.24143086817602652,0.5832629155020134,-0.10910107725747438,-2.6170281567832685,-0.30839382957997863,0.1493999725419618,-1.0828695011676135,0.6434302553162722,0.021154959123965873,0.021154959123965873,0.6434302553162722,1.0527824505275314,0.5226553678023891,-0.04371782774137989,0.08552503374798644,0.021154959123965873,0.9955294106635983,-0.10910107725747438,0.5226553678023891,0.8213525930752211,0.021154959123965873,0.08552503374798644,0.2756939090187885,1.222199240405792,0.9955294106635983,1.0527824505275314,0.1493999725419618,0.6434302553162722,0.021154959123965873,0.8213525930752211,-0.10910107725747438,-0.04371782774137989,-0.7928498829766004,-1.009414400019985,0.5226553678023891,0.3381272349672459,1.222199240405792,2.4168980616095,0.8213525930752211,-0.5125776294717194,-0.24143086817602652,0.3381272349672459,0.21278718307129618,0.6434302553162722
| 3,216
|
Lysosome
| 12
| 39
| 2.279495
| 0.022638
|
P07858,P50897,Q93050,Q9Y487,P04062,P11717,Q9UJY4,O75503,P16278,P54802,O14773,Q15904
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
154,130,12,45,135,286,87,19,88,235,117,379
|
1602,2562,117,1359,2289,19,135,1369,363,827,2488,154,3020,2198,2662,592,828,286,3198,1495,88,2955,130,839,235,3093,842,1877,2506,2338,685,379,12,2373,646,1235,87,959,45
|
-0.04371782774137989,-0.6515356333511229,1.550946556196765,0.08552503374798644,-0.4439584005973705,3.502094791440086,1.4428130982976093,0.08552503374798644,0.8798200308586908,0.4616012571920667,-0.5817669225092277,1.3882100669604411,-1.307191595712573,-0.37590010541019514,-0.7218933461099717,0.6434302553162722,0.4616012571920667,1.0527824505275314,-2.7060722887314697,0.021154959123965873,1.7630487741502214,-1.1569763978106686,1.4970570622608441,0.4616012571920667,1.1661121430364376,-1.5376986032329918,0.4616012571920667,-0.17500271918170665,-0.5817669225092277,-0.4439584005973705,0.5832629155020134,0.8798200308586908,4.49741358097412,-0.4439584005973705,0.6434302553162722,0.21278718307129618,1.815231903298355,0.40009409100938204,2.4651035119965186
| 3,216
|
Lipid biosynthesis
| 9
| 55
| 2.279029
| 0.022665
|
Q96G23,P38398,Q14739,Q15392,Q8NF37,Q15125,P48449,Q9NWU1,P37268
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
32,68,16,17,217,22,23,165,29
|
1134,3085,2561,2393,885,1611,824,2192,3192,2663,29,68,23,3150,1995,2219,2323,2002,1180,845,3200,1410,2511,16,22,764,1533,17,1092,1190,922,1418,2445,2140,215,3182,1313,217,1206,1319,438,2624,2367,32,1442,2697,1930,1700,1228,165,2829,1823,2068,2705,2913
|
0.21278718307129618,-1.5376986032329918,-0.6515356333511229,-0.5125776294717194,0.40009409100938204,-0.04371782774137989,0.4616012571920667,-0.37590010541019514,-2.6170281567832685,-0.7218933461099717,2.9774643320795486,1.9698254903525632,3.41696171884832,-1.9365664874383406,-0.24143086817602652,-0.37590010541019514,-0.4439584005973705,-0.24143086817602652,0.21278718307129618,0.4616012571920667,-2.8869049974604595,0.08552503374798644,-0.5817669225092277,3.711122412271352,3.459639186376742,0.5226553678023891,0.021154959123965873,3.5863493747714164,0.2756939090187885,0.21278718307129618,0.40009409100938204,0.08552503374798644,-0.5125776294717194,-0.30839382957997863,1.222199240405792,-2.355356056585581,0.1493999725419618,1.222199240405792,0.21278718307129618,0.1493999725419618,0.8213525930752211,-0.6515356333511229,-0.4439584005973705,2.886659085145426,0.08552503374798644,-0.7218933461099717,-0.17500271918170665,-0.04371782774137989,0.21278718307129618,1.3882100669604411,-0.8644153121428026,-0.10910107725747438,-0.24143086817602652,-0.7218933461099717,-1.009414400019985
| 3,216
|
Protein localization to endoplasmic reticulum
| 7
| 33
| 2.278821
| 0.022678
|
P24390,P09132,Q96HY6,P46379,Q9NQC3,O15027,P33908
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
3,364,181,109,224,169,81
|
169,1353,1359,1252,1958,1852,364,2792,3,81,1503,109,2799,1873,2596,907,3053,841,1282,2960,1090,1787,1673,2138,858,181,1929,1026,224,1825,1469,453,1476
|
1.3332432815151989,0.08552503374798644,0.08552503374798644,0.1493999725419618,-0.24143086817602652,-0.17500271918170665,0.8798200308586908,-0.8644153121428026,6.273729161291968,1.815231903298355,0.021154959123965873,1.6044860903155633,-0.8644153121428026,-0.17500271918170665,-0.6515356333511229,0.40009409100938204,-1.3833236694797724,0.4616012571920667,0.1493999725419618,-1.1569763978106686,0.2756939090187885,-0.10910107725747438,-0.04371782774137989,-0.30839382957997863,0.4616012571920667,1.3332432815151989,-0.17500271918170665,0.3381272349672459,1.222199240405792,-0.10910107725747438,0.08552503374798644,0.8213525930752211,0.08552503374798644
| 3,216
|
Vacuole organization
| 12
| 50
| 2.276804
| 0.022798
|
Q9BZG1,Q9P253,P50897,Q9Y4P1,Q9ULC3,Q9UJC3,P04062,O75503,Q9H269,P54802,O14773,Q6IAA8
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
134,33,130,310,455,76,135,19,393,235,117,211
|
1602,117,2483,19,1485,1256,888,590,135,3106,2488,2662,832,2491,744,1991,1872,130,2321,235,907,2005,1520,2807,2747,1787,2347,211,1904,2897,1318,1918,1441,2040,1561,134,945,393,1453,1026,1461,2466,33,76,455,1125,2871,1595,520,310
|
-0.04371782774137989,1.550946556196765,-0.5817669225092277,3.502094791440086,0.021154959123965873,0.1493999725419618,0.40009409100938204,0.6434302553162722,1.4428130982976093,-1.6159672087429346,-0.5817669225092277,-0.7218933461099717,0.4616012571920667,-0.5817669225092277,0.5226553678023891,-0.24143086817602652,-0.17500271918170665,1.4970570622608441,-0.4439584005973705,1.1661121430364376,0.40009409100938204,-0.24143086817602652,0.021154959123965873,-0.8644153121428026,-0.7928498829766004,-0.10910107725747438,-0.4439584005973705,1.222199240405792,-0.17500271918170665,-1.009414400019985,0.1493999725419618,-0.17500271918170665,0.08552503374798644,-0.24143086817602652,0.021154959123965873,1.4970570622608441,0.40009409100938204,0.8798200308586908,0.08552503374798644,0.3381272349672459,0.08552503374798644,-0.5125776294717194,2.886659085145426,1.9186162670977254,0.8213525930752211,0.2756939090187885,-0.9365999560555965,0.021154959123965873,0.7624690661744893,1.0527824505275314
| 3,216
|
Isoprenoid metabolic process
| 8
| 23
| 2.270739
| 0.023163
|
Q9HBH5,Q8NBN7,Q86YH6,Q9HB40,P48449,P29375,O60678,P37268
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
450,296,144,47,23,472,330,29
|
330,1843,829,2663,2199,472,29,23,1514,1877,1180,845,2511,764,1094,1095,144,296,1549,2769,47,450,653
|
0.9378771015302817,-0.17500271918170665,0.4616012571920667,-0.7218933461099717,-0.37590010541019514,0.7624690661744893,2.9774643320795486,3.41696171884832,0.021154959123965873,-0.17500271918170665,0.21278718307129618,0.4616012571920667,-0.5817669225092277,0.5226553678023891,0.2756939090187885,0.2756939090187885,1.4428130982976093,1.0527824505275314,0.021154959123965873,-0.7928498829766004,2.4168980616095,0.8213525930752211,0.6434302553162722
| 3,216
|
Inorganic anion transport
| 10
| 19
| 2.241812
| 0.024974
|
Q9H0H5,Q9UBX3,P45880,Q96S66,Q9UHG3,Q8TDW0,P21796,Q9Y696,Q9Y6M7,Q9BXP2
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
449,515,69,244,11,628,77,814,656,797
|
726,1359,77,2884,69,1394,1875,1286,2230,2815,628,244,797,449,515,11,1039,814,656
|
0.5226553678023891,0.08552503374798644,1.8670863906456077,-1.009414400019985,1.9698254903525632,0.08552503374798644,-0.17500271918170665,0.1493999725419618,-0.37590010541019514,-0.8644153121428026,0.6434302553162722,1.1661121430364376,0.5226553678023891,0.8213525930752211,0.7624690661744893,4.60906581420569,0.3381272349672459,0.5226553678023891,0.6434302553162722
| 3,216
|
Regulation of proteasomal ubiquitin dependent protein catabolic process
| 27
| 52
| 2.24105
| 0.025023
|
P78559,Q9NZL4,P04062,Q92990,Q8NEZ5,P10398,O75925,Q96HY6,P54578,O15294,Q9BW61,P55072,P48506,Q96KB5,O14965,Q9UL15,Q93009,Q9C0D3,Q9Y5K5,Q86UE8,Q99497,Q9UNE7,Q9NRR5,P45974,Q9Y4X5,O95816,P46379
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
481,149,135,703,435,892,886,181,174,403,863,538,904,324,311,71,1012,639,359,494,790,1036,643,835,812,589,109
|
964,311,1604,403,1354,1252,1607,886,2655,1257,589,135,2196,2572,892,1067,835,109,904,2320,1873,1393,174,2801,538,2004,1401,2601,1285,481,2674,2962,1668,494,1908,435,2450,703,1012,181,324,790,863,639,643,149,71,1831,1036,812,1599,359
|
0.3381272349672459,0.9955294106635983,-0.04371782774137989,0.8213525930752211,0.08552503374798644,0.1493999725419618,-0.04371782774137989,0.40009409100938204,-0.7218933461099717,0.1493999725419618,0.6434302553162722,1.4428130982976093,-0.37590010541019514,-0.6515356333511229,0.40009409100938204,0.2756939090187885,0.4616012571920667,1.6044860903155633,0.40009409100938204,-0.4439584005973705,-0.17500271918170665,0.08552503374798644,1.3332432815151989,-0.8644153121428026,0.7031636084840797,-0.24143086817602652,0.08552503374798644,-0.6515356333511229,0.1493999725419618,0.7624690661744893,-0.7218933461099717,-1.1569763978106686,-0.04371782774137989,0.7624690661744893,-0.17500271918170665,0.8213525930752211,-0.5125776294717194,0.5832629155020134,0.3381272349672459,1.3332432815151989,0.9955294106635983,0.5226553678023891,0.4616012571920667,0.6434302553162722,0.6434302553162722,1.4428130982976093,1.9698254903525632,-0.10910107725747438,0.3381272349672459,0.5226553678023891,0.021154959123965873,0.9378771015302817
| 3,216
|
Cellular monovalent inorganic cation homeostasis
| 6
| 22
| 2.239954
| 0.025094
|
P50897,Q93050,Q9Y487,O75503,Q92544,Q15904
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
130,12,45,19,271,379
|
19,1256,1743,1613,3161,1629,130,2321,2590,1875,842,911,2747,379,271,12,1918,454,1235,45,814,656
|
3.502094791440086,0.1493999725419618,-0.10910107725747438,-0.04371782774137989,-2.018669375001116,-0.04371782774137989,1.4970570622608441,-0.4439584005973705,-0.6515356333511229,-0.17500271918170665,0.4616012571920667,0.40009409100938204,-0.7928498829766004,0.8798200308586908,1.1096416031090883,4.49741358097412,-0.17500271918170665,0.8213525930752211,0.21278718307129618,2.4651035119965186,0.5226553678023891,0.6434302553162722
| 3,216
|
Positive regulation of protein catabolic process
| 29
| 66
| 2.224307
| 0.026128
|
Q13596,Q9NZJ0,Q9NZL4,P62195,P04062,Q96J02,Q8NEZ5,O95352,O75925,O43847,Q96HY6,P62333,Q06787,Q6ZXV5,Q9BW61,P55072,O14965,Q9Y5X1,Q8NF37,Q9C0D3,P53634,Q13190,P45974,Q96JB5,Q9Y4X5,O95816,Q9UNN5,P46379,P43686
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
485,281,149,606,135,564,435,888,886,152,181,908,912,292,863,538,311,80,217,639,839,102,835,389,812,589,810,109,474
|
311,1252,152,1733,1051,2483,1607,886,888,1257,589,135,2400,2572,1375,1977,1064,1983,2104,1169,474,835,109,1993,904,2320,2321,1873,1393,839,538,2423,606,908,1401,1285,3057,912,102,485,2340,2962,1668,1093,292,1799,435,217,181,564,389,1561,1446,863,639,1453,281,149,1238,1239,1831,1036,810,812,1599,80
|
0.9955294106635983,0.1493999725419618,1.3882100669604411,-0.10910107725747438,0.2756939090187885,-0.5817669225092277,-0.04371782774137989,0.40009409100938204,0.40009409100938204,0.1493999725419618,0.6434302553162722,1.4428130982976093,-0.5125776294717194,-0.6515356333511229,0.08552503374798644,-0.24143086817602652,0.2756939090187885,-0.24143086817602652,-0.30839382957997863,0.21278718307129618,0.7624690661744893,0.4616012571920667,1.6044860903155633,-0.24143086817602652,0.40009409100938204,-0.4439584005973705,-0.4439584005973705,-0.17500271918170665,0.08552503374798644,0.4616012571920667,0.7031636084840797,-0.5125776294717194,0.6434302553162722,0.40009409100938204,0.08552503374798644,0.1493999725419618,-1.3833236694797724,0.40009409100938204,1.657680089871788,0.7624690661744893,-0.4439584005973705,-1.1569763978106686,-0.04371782774137989,0.2756939090187885,1.0527824505275314,-0.10910107725747438,0.8213525930752211,1.222199240405792,1.3332432815151989,0.7031636084840797,0.8798200308586908,0.021154959123965873,0.08552503374798644,0.4616012571920667,0.6434302553162722,0.08552503374798644,1.1096416031090883,1.4428130982976093,0.21278718307129618,0.21278718307129618,-0.10910107725747438,0.3381272349672459,0.5226553678023891,0.5226553678023891,0.021154959123965873,1.8670863906456077
| 3,216
|
Xenobiotic metabolic process
| 6
| 15
| 2.215725
| 0.02671
|
P78417,P07099,O43169,P09110,P33121,Q9HBK9
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
194,46,14,468,473,164
|
2647,14,46,468,1856,896,674,535,473,194,2011,937,1025,164,1600
|
-0.7218933461099717,4.191950452921439,2.4168980616095,0.7624690661744893,-0.17500271918170665,0.40009409100938204,0.5832629155020134,0.7031636084840797,0.7624690661744893,1.277907963516101,-0.24143086817602652,0.40009409100938204,0.3381272349672459,1.3882100669604411,0.021154959123965873
| 3,216
|
Golgi cisterna
| 6
| 17
| 2.21225
| 0.026949
|
Q9BZG1,Q96JB2,Q9H4A6,Q08378,Q15363,Q96L58
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
134,133,183,120,344,161
|
1248,1368,1873,120,2607,374,1524,914,1667,344,1318,133,161,1110,134,183,3103
|
0.1493999725419618,0.08552503374798644,-0.17500271918170665,1.550946556196765,-0.6515356333511229,0.8798200308586908,0.021154959123965873,0.40009409100938204,-0.04371782774137989,0.9378771015302817,0.1493999725419618,1.4970570622608441,1.3882100669604411,0.2756939090187885,1.4970570622608441,1.3332432815151989,-1.5376986032329918
| 3,216
|
Phosphatase
| 10
| 33
| 2.208388
| 0.027217
|
Q5TFE4,P63151,P62140,Q8TF05,A6NDG6,P18433,Q16537,Q13614,Q86YN1,P49593
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
132,421,420,243,185,172,345,210,433,62
|
185,878,1359,1485,737,1974,172,1268,833,743,2957,2412,62,2414,1996,419,420,421,1883,210,2516,345,132,433,1201,243,1108,1930,1451,1117,1573,1118,873
|
1.277907963516101,0.40009409100938204,0.08552503374798644,0.021154959123965873,0.5226553678023891,-0.24143086817602652,1.3332432815151989,0.1493999725419618,0.4616012571920667,0.5226553678023891,-1.1569763978106686,-0.5125776294717194,2.1215677563097355,-0.5125776294717194,-0.24143086817602652,0.8213525930752211,0.8213525930752211,0.8213525930752211,-0.17500271918170665,1.222199240405792,-0.5817669225092277,0.9378771015302817,1.4970570622608441,0.8213525930752211,0.21278718307129618,1.1661121430364376,0.2756939090187885,-0.17500271918170665,0.08552503374798644,0.2756939090187885,0.021154959123965873,0.2756939090187885,0.4616012571920667
| 3,216
|
Negative regulation of proteasomal ubiquitin dependent protein catabolic process
| 8
| 19
| 2.205047
| 0.027451
|
Q9UL15,Q96HY6,P54578,O15294,P46379,Q9Y5K5,Q86UE8,Q96KB5
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
71,181,174,403,109,359,494,324
|
964,403,1354,1252,2196,109,174,2601,481,2674,494,1908,2450,1012,181,324,790,71,359
|
0.3381272349672459,0.8213525930752211,0.08552503374798644,0.1493999725419618,-0.37590010541019514,1.6044860903155633,1.3332432815151989,-0.6515356333511229,0.7624690661744893,-0.7218933461099717,0.7624690661744893,-0.17500271918170665,-0.5125776294717194,0.3381272349672459,1.3332432815151989,0.9955294106635983,0.5226553678023891,1.9698254903525632,0.9378771015302817
| 3,216
|
Regulation of ph
| 6
| 18
| 2.204703
| 0.027475
|
P50897,Q93050,Q9Y487,O75503,Q92544,Q15904
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
130,12,45,19,271,379
|
19,1256,3161,1629,130,2321,842,911,2747,379,271,12,1918,454,1235,45,814,656
|
3.502094791440086,0.1493999725419618,-2.018669375001116,-0.04371782774137989,1.4970570622608441,-0.4439584005973705,0.4616012571920667,0.40009409100938204,-0.7928498829766004,0.8798200308586908,1.1096416031090883,4.49741358097412,-0.17500271918170665,0.8213525930752211,0.21278718307129618,2.4651035119965186,0.5226553678023891,0.6434302553162722
| 3,216
|
Regulation of cellular ph
| 6
| 18
| 2.204703
| 0.027475
|
P50897,Q93050,Q9Y487,O75503,Q92544,Q15904
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
130,12,45,19,271,379
|
19,1256,3161,1629,130,2321,842,911,2747,379,271,12,1918,454,1235,45,814,656
|
3.502094791440086,0.1493999725419618,-2.018669375001116,-0.04371782774137989,1.4970570622608441,-0.4439584005973705,0.4616012571920667,0.40009409100938204,-0.7928498829766004,0.8798200308586908,1.1096416031090883,4.49741358097412,-0.17500271918170665,0.8213525930752211,0.21278718307129618,2.4651035119965186,0.5226553678023891,0.6434302553162722
| 3,216
|
Trna methyltransferase activity
| 8
| 14
| 2.195122
| 0.028155
|
Q9UBP6,Q7Z2T5,Q96BT7,O75648,Q96FX7,O60294,Q9BV44,Q7Z4G4
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
647,549,146,253,442,584,568,696
|
584,253,1081,1085,1886,2023,549,696,146,442,568,1697,647,807
|
0.6434302553162722,1.1096416031090883,0.2756939090187885,0.2756939090187885,-0.17500271918170665,-0.24143086817602652,0.7031636084840797,0.5832629155020134,1.4428130982976093,0.8213525930752211,0.7031636084840797,-0.04371782774137989,0.6434302553162722,0.5226553678023891
| 3,216
|
protease
| 15
| 44
| 2.19139
| 0.028424
|
P49721,P42575,P55036,P25787,P28072,P62195,Q9BT78,O43242,Q7L266,P28070,P55212,P43686,P25789,P49720,P60900
|
Functions
|
Panther Protein class
|
panther_protein_class
|
64,96,480,366,193,606,638,463,621,136,82,474,595,414,539
|
816,1726,3015,463,1609,1847,1064,1496,2095,366,1068,595,1861,136,193,898,1169,2210,96,474,1639,414,64,1511,480,604,82,539,3053,2423,606,908,1659,1090,621,1813,1328,638,2056,2161,1230,1346,1594,2469
|
0.4616012571920667,-0.10910107725747438,-1.307191595712573,0.7624690661744893,-0.04371782774137989,-0.17500271918170665,0.2756939090187885,0.021154959123965873,-0.30839382957997863,0.8798200308586908,0.2756939090187885,0.6434302553162722,-0.17500271918170665,1.4428130982976093,1.277907963516101,0.40009409100938204,0.21278718307129618,-0.37590010541019514,1.7105328972774696,0.7624690661744893,-0.04371782774137989,0.8213525930752211,2.020717946656322,0.021154959123965873,0.7624690661744893,0.6434302553162722,1.815231903298355,0.7031636084840797,-1.3833236694797724,-0.5125776294717194,0.6434302553162722,0.40009409100938204,-0.04371782774137989,0.2756939090187885,0.6434302553162722,-0.10910107725747438,0.1493999725419618,0.6434302553162722,-0.24143086817602652,-0.30839382957997863,0.21278718307129618,0.1493999725419618,0.021154959123965873,-0.5125776294717194
| 3,216
|
Regulation of proteasomal protein catabolic process
| 37
| 70
| 2.18985
| 0.028535
|
Q06323,P78559,Q9NZL4,P62195,P04062,Q92990,Q8NEZ5,P10398,O75925,Q96HY6,P62333,P54578,O15294,Q06787,Q6ZXV5,P60520,Q96KB5,P55072,Q9BW61,P48506,O14965,Q9UL15,Q93009,Q9C0D3,Q9Y5K5,Q86UE8,Q99497,Q92530,Q9UNE7,Q9UL46,Q9NRR5,P45974,Q9Y4X5,O95816,P43686,P46379,O14908
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
612,481,149,606,135,703,435,892,886,181,908,174,403,912,292,907,324,538,863,904,311,71,1012,639,359,494,790,783,1036,248,643,835,812,589,474,109,964
|
2479,964,311,1604,403,1354,1252,1051,1607,886,2655,1366,1257,589,135,2196,2572,892,1377,1064,1067,1169,474,835,109,904,2320,1873,1393,174,2801,538,907,2004,988,2423,606,908,1401,2601,1285,481,2674,612,912,2962,1668,292,494,1908,435,783,2450,703,1012,181,324,790,863,639,2768,643,149,71,248,1831,1036,812,1599,359
|
-0.5817669225092277,0.3381272349672459,0.9955294106635983,-0.04371782774137989,0.8213525930752211,0.08552503374798644,0.1493999725419618,0.2756939090187885,-0.04371782774137989,0.40009409100938204,-0.7218933461099717,0.08552503374798644,0.1493999725419618,0.6434302553162722,1.4428130982976093,-0.37590010541019514,-0.6515356333511229,0.40009409100938204,0.08552503374798644,0.2756939090187885,0.2756939090187885,0.21278718307129618,0.7624690661744893,0.4616012571920667,1.6044860903155633,0.40009409100938204,-0.4439584005973705,-0.17500271918170665,0.08552503374798644,1.3332432815151989,-0.8644153121428026,0.7031636084840797,0.40009409100938204,-0.24143086817602652,0.3381272349672459,-0.5125776294717194,0.6434302553162722,0.40009409100938204,0.08552503374798644,-0.6515356333511229,0.1493999725419618,0.7624690661744893,-0.7218933461099717,0.6434302553162722,0.40009409100938204,-1.1569763978106686,-0.04371782774137989,1.0527824505275314,0.7624690661744893,-0.17500271918170665,0.8213525930752211,0.5226553678023891,-0.5125776294717194,0.5832629155020134,0.3381272349672459,1.3332432815151989,0.9955294106635983,0.5226553678023891,0.4616012571920667,0.6434302553162722,-0.7928498829766004,0.6434302553162722,1.4428130982976093,1.9698254903525632,1.1661121430364376,-0.10910107725747438,0.3381272349672459,0.5226553678023891,0.021154959123965873,0.9378771015302817
| 3,216
|
Increased intracranial pressure
| 9
| 17
| 2.186667
| 0.028767
|
Q12824,Q9NZJ7,P54277,Q96JJ3,Q9NZ08,Q15437,P43246,P10644,Q969G3
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
758,646,479,630,51,264,747,469,860
|
827,469,1859,1864,747,1995,1078,985,479,1397,758,264,1535,860,630,51,646
|
0.4616012571920667,0.7624690661744893,-0.17500271918170665,-0.17500271918170665,0.5226553678023891,-0.24143086817602652,0.2756939090187885,0.3381272349672459,0.7624690661744893,0.08552503374798644,0.5226553678023891,1.1096416031090883,0.021154959123965873,0.4616012571920667,0.6434302553162722,2.3196296243830314,0.6434302553162722
| 3,216
|
Abnormal enchondral ossification
| 7
| 24
| 2.185902
| 0.028823
|
Q96HY6,Q14739,P50542,Q15125,Q5F1R6,Q9NUQ7,Q96L58
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
181,16,137,22,381,513,161
|
1134,1845,1052,1055,2658,469,2091,2841,899,137,841,1781,16,688,22,1092,381,2148,181,161,513,2068,2705,1597
|
0.21278718307129618,-0.17500271918170665,0.2756939090187885,0.2756939090187885,-0.7218933461099717,0.7624690661744893,-0.30839382957997863,-0.9365999560555965,0.40009409100938204,1.4428130982976093,0.4616012571920667,-0.10910107725747438,3.711122412271352,0.5832629155020134,3.459639186376742,0.2756939090187885,0.8798200308586908,-0.30839382957997863,1.3332432815151989,1.3882100669604411,0.7624690661744893,-0.24143086817602652,-0.7218933461099717,0.021154959123965873
| 3,216
|
Hormone mediated signaling pathway
| 11
| 48
| 2.181396
| 0.029154
|
Q9P253,P42785,P12931,P38398,Q96HY6,Q06124,Q969T9,Q9NS86,Q9UKG1,P11474,Q9GZZ9
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
33,4,191,68,181,289,54,56,166,57,304
|
2392,2180,2783,3148,2954,2655,2294,2302,57,191,2577,2984,473,2207,68,4,2800,1648,1402,1777,2121,911,289,314,686,2811,1533,2854,1790,2131,3145,855,2860,1011,2035,54,1438,181,790,3170,304,1453,56,513,871,33,1586,166
|
-0.5125776294717194,-0.37590010541019514,-0.8644153121428026,-1.9365664874383406,-1.1569763978106686,-0.7218933461099717,-0.4439584005973705,-0.4439584005973705,2.2211954204950515,1.277907963516101,-0.6515356333511229,-1.2317465192005141,0.7624690661744893,-0.37590010541019514,1.9698254903525632,6.273729161291968,-0.8644153121428026,-0.04371782774137989,0.08552503374798644,-0.10910107725747438,-0.30839382957997863,0.40009409100938204,1.0527824505275314,0.9955294106635983,0.5832629155020134,-0.8644153121428026,0.021154959123965873,-0.9365999560555965,-0.10910107725747438,-0.30839382957997863,-1.85525960192129,0.4616012571920667,-0.9365999560555965,0.3381272349672459,-0.24143086817602652,2.2705599514252803,0.08552503374798644,1.3332432815151989,0.5226553678023891,-2.101583678206865,1.0527824505275314,0.08552503374798644,2.2705599514252803,0.7624690661744893,0.4616012571920667,2.886659085145426,0.021154959123965873,1.3882100669604411
| 3,216
|
Other group
| 7
| 15
| 2.178652
| 0.029358
|
O14965,Q9UHY1,O14976,Q8TD19,Q86UE8,O15111,Q96KB5
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
311,517,283,495,494,580,324
|
311,283,580,2481,1483,1753,677,1393,494,495,324,1692,2044,1830,517
|
0.9955294106635983,1.0527824505275314,0.6434302553162722,-0.5817669225092277,0.021154959123965873,-0.10910107725747438,0.5832629155020134,0.08552503374798644,0.7624690661744893,0.7624690661744893,0.9955294106635983,-0.04371782774137989,-0.24143086817602652,-0.10910107725747438,0.7624690661744893
| 3,216
|
Brittle hair
| 6
| 16
| 2.177706
| 0.029428
|
O75844,Q15477,O60828,Q9Y487,P49589,Q9Y276
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
101,426,188,45,600,456
|
188,101,1379,1752,1626,2411,600,2008,683,919,426,1677,1421,1935,456,45
|
1.277907963516101,1.657680089871788,0.08552503374798644,-0.10910107725747438,-0.04371782774137989,-0.5125776294717194,0.6434302553162722,-0.24143086817602652,0.5832629155020134,0.40009409100938204,0.8213525930752211,-0.04371782774137989,0.08552503374798644,-0.17500271918170665,0.8213525930752211,2.4651035119965186
| 3,216
|
Regulation of dendritic spine development
| 9
| 14
| 2.172906
| 0.029787
|
Q14444,Q9NUL3,Q9UJU6,P61160,Q16643,Q06787,Q05086,Q92769,Q9UQB8
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
763,308,518,752,265,912,911,702,31
|
1765,752,1082,1651,911,912,1656,763,265,702,1027,308,518,31
|
-0.10910107725747438,0.5226553678023891,0.2756939090187885,-0.04371782774137989,0.40009409100938204,0.40009409100938204,-0.04371782774137989,0.5226553678023891,1.1096416031090883,0.5832629155020134,0.3381272349672459,1.0527824505275314,0.7624690661744893,2.932187583429893
| 3,216
|
Cellular hormone metabolic process
| 6
| 17
| 2.162967
| 0.030544
|
Q6UWP2,Q8NBN7,Q9HB40,O95470,Q92506,O60678
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
214,296,47,171,438,330
|
330,171,2199,2884,2111,1790,1418,1095,214,296,1313,1549,438,1021,47,450,653
|
0.9378771015302817,1.3332432815151989,-0.37590010541019514,-1.009414400019985,-0.30839382957997863,-0.10910107725747438,0.08552503374798644,0.2756939090187885,1.222199240405792,1.0527824505275314,0.1493999725419618,0.021154959123965873,0.8213525930752211,0.3381272349672459,2.4168980616095,0.8213525930752211,0.6434302553162722
| 3,216
|
Alcohol metabolic process
| 12
| 79
| 2.160082
| 0.030766
|
P35610,Q8WTV0,Q8NBN7,A6NDG6,P04062,Q14739,Q15392,Q92551,Q15125,P48449,Q13614,P37268
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
129,297,296,185,135,16,17,123,22,23,210,29
|
185,876,877,659,2184,1843,3017,885,1608,1961,737,2192,135,889,3090,1063,829,2663,1374,2199,896,2883,1163,1268,1630,1384,129,29,1635,901,23,1390,1391,1277,2419,1078,984,1514,2219,2002,751,2847,1877,2227,1882,1180,1883,845,1524,1410,685,2236,210,2511,16,22,764,17,1092,769,1190,1095,3182,2894,296,1549,297,123,790,2273,2050,2769,450,1228,356,2068,1588,1037,653
|
1.277907963516101,0.40009409100938204,0.40009409100938204,0.5832629155020134,-0.37590010541019514,-0.17500271918170665,-1.307191595712573,0.40009409100938204,-0.04371782774137989,-0.24143086817602652,0.5226553678023891,-0.37590010541019514,1.4428130982976093,0.40009409100938204,-1.5376986032329918,0.2756939090187885,0.4616012571920667,-0.7218933461099717,0.08552503374798644,-0.37590010541019514,0.40009409100938204,-1.009414400019985,0.21278718307129618,0.1493999725419618,-0.04371782774137989,0.08552503374798644,1.4970570622608441,2.9774643320795486,-0.04371782774137989,0.40009409100938204,3.41696171884832,0.08552503374798644,0.08552503374798644,0.1493999725419618,-0.5125776294717194,0.2756939090187885,0.3381272349672459,0.021154959123965873,-0.37590010541019514,-0.24143086817602652,0.5226553678023891,-0.9365999560555965,-0.17500271918170665,-0.37590010541019514,-0.17500271918170665,0.21278718307129618,-0.17500271918170665,0.4616012571920667,0.021154959123965873,0.08552503374798644,0.5832629155020134,-0.37590010541019514,1.222199240405792,-0.5817669225092277,3.711122412271352,3.459639186376742,0.5226553678023891,3.5863493747714164,0.2756939090187885,0.5226553678023891,0.21278718307129618,0.2756939090187885,-2.355356056585581,-1.009414400019985,1.0527824505275314,0.021154959123965873,1.0527824505275314,1.550946556196765,0.5226553678023891,-0.37590010541019514,-0.24143086817602652,-0.7928498829766004,0.8213525930752211,0.21278718307129618,0.9378771015302817,-0.24143086817602652,0.021154959123965873,0.3381272349672459,0.6434302553162722
| 3,216
|
Uch proteinases
| 17
| 48
| 2.159957
| 0.030776
|
P49721,Q06323,P55036,P25787,P28072,Q9UL46,P25789,Q8NB78,O43242,Q9Y265,O15294,P28070,Q9Y5K5,P43686,P85037,P49720,P60900
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
64,612,480,366,193,248,595,352,463,398,403,136,359,474,119,414,539
|
962,816,1726,2479,3015,403,463,1607,1367,1064,1496,2095,366,1068,595,1861,136,193,898,1169,474,1639,414,64,1641,2732,480,539,988,2423,606,908,119,612,1659,3075,2130,1299,352,783,1813,1328,1446,248,2643,1346,398,359
|
0.3381272349672459,0.4616012571920667,-0.10910107725747438,-0.5817669225092277,-1.307191595712573,0.8213525930752211,0.7624690661744893,-0.04371782774137989,0.08552503374798644,0.2756939090187885,0.021154959123965873,-0.30839382957997863,0.8798200308586908,0.2756939090187885,0.6434302553162722,-0.17500271918170665,1.4428130982976093,1.277907963516101,0.40009409100938204,0.21278718307129618,0.7624690661744893,-0.04371782774137989,0.8213525930752211,2.020717946656322,-0.04371782774137989,-0.7928498829766004,0.7624690661744893,0.7031636084840797,0.3381272349672459,-0.5125776294717194,0.6434302553162722,0.40009409100938204,1.550946556196765,0.6434302553162722,-0.04371782774137989,-1.460155105498623,-0.30839382957997863,0.1493999725419618,0.9378771015302817,0.5226553678023891,-0.10910107725747438,0.1493999725419618,0.08552503374798644,1.1661121430364376,-0.6515356333511229,0.1493999725419618,0.8798200308586908,0.9378771015302817
| 3,216
|
Slender long bone
| 7
| 14
| 2.154921
| 0.031168
|
Q15813,Q53GS7,Q9Y487,Q96J02,Q96L58,P37268,O43929
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
427,347,45,564,161,29,206
|
206,2724,29,2612,427,618,1671,347,1321,564,161,2271,1026,45
|
1.222199240405792,-0.7928498829766004,2.9774643320795486,-0.6515356333511229,0.8213525930752211,0.6434302553162722,-0.04371782774137989,0.9378771015302817,0.1493999725419618,0.7031636084840797,1.3882100669604411,-0.37590010541019514,0.3381272349672459,2.4651035119965186
| 3,216
|
Neuromuscular process
| 9
| 28
| 2.141243
| 0.032254
|
O75844,P78559,P78417,P04062,O75592,P50542,Q8N0X7,Q9GZZ9,O14773
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
101,481,194,135,465,137,350,304,117
|
117,1484,465,101,135,2488,2662,1259,2955,1065,535,1991,1765,2213,137,984,194,481,1783,1667,2136,2688,2144,350,1561,1329,304,2062
|
1.550946556196765,0.021154959123965873,0.7624690661744893,1.657680089871788,1.4428130982976093,-0.5817669225092277,-0.7218933461099717,0.1493999725419618,-1.1569763978106686,0.2756939090187885,0.7031636084840797,-0.24143086817602652,-0.10910107725747438,-0.37590010541019514,1.4428130982976093,0.3381272349672459,1.277907963516101,0.7624690661744893,-0.10910107725747438,-0.04371782774137989,-0.30839382957997863,-0.7218933461099717,-0.30839382957997863,0.9378771015302817,0.021154959123965873,0.1493999725419618,1.0527824505275314,-0.24143086817602652
| 3,216
|
Rhoa gtpase cycle
| 11
| 47
| 2.132133
| 0.032996
|
Q9H0H5,Q13190,P30519,Q96HY6,P14923,Q9UDY2,Q14739,Q92974,O00161,Q92888,Q15904
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
449,102,9,181,257,43,16,439,167,201,379
|
167,402,2396,820,2186,1738,2785,1610,1741,1259,257,2097,9,982,2583,1274,1637,2498,1873,2991,1648,2119,3143,1654,102,484,1294,16,379,3145,616,2856,1801,1318,201,439,1437,181,1110,634,449,1454,2377,715,2064,43,2709
|
1.3332432815151989,0.8213525930752211,-0.5125776294717194,0.4616012571920667,-0.37590010541019514,-0.10910107725747438,-0.8644153121428026,-0.04371782774137989,-0.10910107725747438,0.1493999725419618,1.1096416031090883,-0.30839382957997863,4.719203601847822,0.3381272349672459,-0.6515356333511229,0.1493999725419618,-0.04371782774137989,-0.5817669225092277,-0.17500271918170665,-1.2317465192005141,-0.04371782774137989,-0.30839382957997863,-1.85525960192129,-0.04371782774137989,1.657680089871788,0.7624690661744893,0.1493999725419618,3.711122412271352,0.8798200308586908,-1.85525960192129,0.6434302553162722,-0.9365999560555965,-0.10910107725747438,0.1493999725419618,1.277907963516101,0.8213525930752211,0.08552503374798644,1.3332432815151989,0.2756939090187885,0.6434302553162722,0.8213525930752211,0.08552503374798644,-0.4439584005973705,0.5832629155020134,-0.24143086817602652,2.5130274793029668,-0.7218933461099717
| 3,216
|
Ion homeostasis
| 13
| 102
| 2.131228
| 0.03307
|
Q6P4Q7,P23634,P50897,P12931,Q9HD20,P30519,Q93050,Q9Y487,P78417,O75503,P52306,O76003,Q92544
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
212,36,130,191,42,9,12,45,194,19,139,230,271
|
1602,2562,729,732,820,1733,2293,19,1737,230,2836,1055,1610,1256,1741,3160,1153,1743,1613,826,3161,2488,256,2721,3142,1973,740,2302,2921,1615,191,2573,2304,832,1377,1066,1380,1980,36,534,2984,535,1629,9,2884,1986,744,1272,2211,904,1508,130,2321,1873,139,2590,1875,842,3094,1774,1285,194,609,911,847,1528,848,1291,2934,1296,2747,1667,379,1416,212,1096,1543,1547,626,2261,271,12,559,1918,1686,1112,2159,797,2862,2276,42,2467,454,1235,1938,958,45,2176,1131,814,656,2476
|
-0.04371782774137989,-0.6515356333511229,0.5226553678023891,0.5226553678023891,0.4616012571920667,-0.10910107725747438,-0.4439584005973705,3.502094791440086,-0.10910107725747438,1.1661121430364376,-0.9365999560555965,0.2756939090187885,-0.04371782774137989,0.1493999725419618,-0.10910107725747438,-2.018669375001116,0.21278718307129618,-0.10910107725747438,-0.04371782774137989,0.4616012571920667,-2.018669375001116,-0.5817669225092277,1.1096416031090883,-0.7928498829766004,-1.85525960192129,-0.24143086817602652,0.5226553678023891,-0.4439584005973705,-1.0828695011676135,-0.04371782774137989,1.277907963516101,-0.6515356333511229,-0.4439584005973705,0.4616012571920667,0.08552503374798644,0.2756939090187885,0.08552503374798644,-0.24143086817602652,2.7948357651419897,0.7031636084840797,-1.2317465192005141,0.7031636084840797,-0.04371782774137989,4.719203601847822,-1.009414400019985,-0.24143086817602652,0.5226553678023891,0.1493999725419618,-0.37590010541019514,0.40009409100938204,0.021154959123965873,1.4970570622608441,-0.4439584005973705,-0.17500271918170665,1.4428130982976093,-0.6515356333511229,-0.17500271918170665,0.4616012571920667,-1.5376986032329918,-0.10910107725747438,0.1493999725419618,1.277907963516101,0.6434302553162722,0.40009409100938204,0.4616012571920667,0.021154959123965873,0.4616012571920667,0.1493999725419618,-1.0828695011676135,0.1493999725419618,-0.7928498829766004,-0.04371782774137989,0.8798200308586908,0.08552503374798644,1.222199240405792,0.2756939090187885,0.021154959123965873,0.021154959123965873,0.6434302553162722,-0.37590010541019514,1.1096416031090883,4.49741358097412,0.7031636084840797,-0.17500271918170665,-0.04371782774137989,0.2756939090187885,-0.30839382957997863,0.5226553678023891,-0.9365999560555965,-0.37590010541019514,2.560673166001156,-0.5125776294717194,0.8213525930752211,0.21278718307129618,-0.17500271918170665,0.40009409100938204,2.4651035119965186,-0.30839382957997863,0.2756939090187885,0.5226553678023891,0.6434302553162722,-0.5125776294717194
| 3,216
|
Subsets and Splits
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