term
stringlengths
2
121
overlap
int64
6
281
setsize
int64
7
499
score
float64
1.96
10.6
pval
float64
0
0.05
edge
stringlengths
41
1.97k
type
stringclasses
5 values
subtype
stringclasses
24 values
subtype_key
stringclasses
24 values
edge_idxs
stringlengths
11
1.17k
ann_idxs
stringlengths
19
2.31k
ann_vals
stringlengths
124
9.94k
sig_size
int64
2.2k
3.73k
Cytosolic large ribosomal subunit
31
47
2.498216
0.012482
P18124,P61254,P35268,P47914,Q02878,P62750,P39023,P61513,P62899,Q02543,Q9NP64,P83881,P18077,P26373,P61927,Q9Y3U8,P62910,P62424,P42766,P83731,P51116,Q07020,P63173,P46779,P36578,P84098,P62917,P61313,P46776,P46778,P40429
Localization
GO Cellular component
msigdb_gocc
878,755,999,509,630,1005,508,511,785,656,160,533,1035,1037,423,448,180,926,557,681,809,813,727,476,849,602,365,364,362,628,378
1254,2993,1035,878,1722,1037,1307,2678,2679,999,849,508,378,557,362,2071,628,476,509,1172,1826,809,755,364,1044,511,423,926,1005,1542,2123,785,1400,180,1543,365,727,681,533,602,656,630,813,2024,1601,160,448
0.21636733085825482,-1.3786049993712943,0.34579373996602075,0.44544306819693447,-0.0606293056858646,0.34579373996602075,0.18979526604543842,-0.8067497779060742,-0.8067497779060742,0.3710194511388473,0.4698445071041799,0.7480967979523666,0.8991926986389834,0.7034844439548688,0.9201671263885668,-0.2709736160130218,0.6352911062035237,0.7920526088666452,0.7480967979523666,0.26881271098746073,-0.11924966294507812,0.4940482237889104,0.5418751241716249,0.9201671263885668,0.34579373996602075,0.7480967979523666,0.856796727704752,0.42084065117869884,0.3710194511388473,0.053269504024264246,-0.30221572716540523,0.5180573956646057,0.13593136335059053,1.3478507399601813,0.053269504024264246,0.9201671263885668,0.5655044371788908,0.5889482912953588,0.7258739119100094,0.6581956434453833,0.612209574085093,0.6352911062035237,0.4940482237889104,-0.24003068040751657,0.025199324650836994,1.4545942332074184,0.8353709145003145
3,193
Metabolism of steroids
10
45
2.495944
0.012562
O14734,P48449,Q9BWD1,P30536,Q15392,Q9UBM7,Q14739,Q16850,O95487,P04062
Processes and pathways
Reactome Pathways
msigdb_reactome
251,99,4,100,70,141,175,93,213,158
2051,506,251,1564,995,213,507,158,2397,2116,2318,2065,3102,100,1573,1091,99,1577,2167,2511,1870,784,2516,2862,1641,1320,175,294,2836,1879,1834,70,1455,1739,1880,381,93,732,1886,1329,942,4,2767,667,141
-0.2709736160130218,0.7480967979523666,1.102589523776575,0.025199324650836994,0.3710194511388473,1.1993188415722877,0.7480967979523666,1.4545942332074184,-0.5292875863064875,-0.30221572716540523,-0.462913985518726,-0.2709736160130218,-1.8407550802597537,1.8007392900685555,0.025199324650836994,0.3203531886001632,1.8317054739763257,0.025199324650836994,-0.3337570158659335,-0.631091924935383,-0.14899690656748693,0.5180573956646057,-0.631091924935383,-1.065237448909853,-0.0031371136066703498,0.18979526604543842,1.3659083845750073,1.0430115443451933,-1.0274130001280428,-0.14899690656748693,-0.11924966294507812,2.1802255667070183,0.10863077097339395,-0.0606293056858646,-0.14899690656748693,0.8991926986389834,1.9077445032407137,0.5655044371788908,-0.14899690656748693,0.18979526604543842,0.42084065117869884,4.665813426727727,-0.9157349411807121,0.612209574085093,1.5576536448951719
3,193
Glycosylation
12
44
2.49552
0.012577
Q9H488,O43505,Q2TAA5,O60476,Q9BV10,O15294,O60502,O15118,Q8WTW3,O75503,Q9BT22,P04062
Processes and pathways
GO Biological process
msigdb_gobp
230,39,108,419,115,174,300,208,245,184,91,158
2421,208,174,2639,39,419,300,2113,2056,1563,184,2311,158,1819,1440,2276,1171,1448,1922,2242,1971,814,2286,1318,789,108,658,1459,1224,2600,245,1413,828,91,115,2768,230,1192,469,2417,947,1340,1759,2157
-0.5629231723307153,1.2182943630695027,1.3659083845750073,-0.7710198034073763,2.7180994529009332,0.856796727704752,1.0228851550061475,-0.30221572716540523,-0.2709736160130218,0.025199324650836994,1.3296832447901088,-0.462913985518726,1.4545942332074184,-0.11924966294507812,0.10863077097339395,-0.4301759669868179,0.26881271098746073,0.10863077097339395,-0.1790423277350827,-0.3977371338220593,-0.20938691832830006,0.4940482237889104,-0.4301759669868179,0.18979526604543842,0.5180573956646057,1.7536794627358119,0.612209574085093,0.10863077097339395,0.2427051145911597,-0.7004574638193659,1.1221876398575348,0.13593136335059053,0.4940482237889104,1.9227226839549494,1.6735598720423626,-0.9157349411807121,1.1802219848882647,0.26881271098746073,0.813790292416791,-0.5292875863064875,0.42084065117869884,0.18979526604543842,-0.0606293056858646,-0.30221572716540523
3,193
Cross presentation of soluble exogenous antigens endosomes
7
37
2.49492
0.012599
P49721,P28074,P28072,P25787,P28070,P60900,P20618
Processes and pathways
Reactome Pathways
msigdb_reactome
8,105,20,119,55,30,95
525,2356,1907,2050,1993,417,913,1916,95,2467,119,2162,2468,2400,55,20,105,2996,2998,1261,1446,8,352,3068,30,478,1631,2434,2802,729,1545,167,929,795,2143,1523,1295
0.7258739119100094,-0.49595119132772597,-0.1790423277350827,-0.2709736160130218,-0.24003068040751657,0.856796727704752,0.42084065117869884,-0.1790423277350827,1.8775608468012885,-0.5968579512594566,1.6409002994968682,-0.3337570158659335,-0.5968579512594566,-0.5292875863064875,2.301101464563815,3.308198222205599,1.7694486191853893,-1.3786049993712943,-1.3786049993712943,0.21636733085825482,0.10863077097339395,4.132037847844936,0.9409952878769652,-1.6685111568748416,3.0017959971834336,0.7920526088666452,-0.0031371136066703498,-0.5629231723307153,-0.9898877670258749,0.5655044371788908,0.053269504024264246,1.41943529737493,0.42084065117869884,0.5180573956646057,-0.30221572716540523,0.08107837999042887,0.21636733085825482
3,193
Degradation of axin
7
37
2.49492
0.012599
P49721,P28074,P28072,P25787,P28070,P60900,P20618
Processes and pathways
Reactome Pathways
msigdb_reactome
8,105,20,119,55,30,95
525,2356,1907,2050,1993,417,913,1916,95,2467,119,2162,2468,2400,55,20,105,2996,2998,1261,1446,8,352,3068,30,478,1631,2434,2802,729,1545,167,929,795,2143,1523,1295
0.7258739119100094,-0.49595119132772597,-0.1790423277350827,-0.2709736160130218,-0.24003068040751657,0.856796727704752,0.42084065117869884,-0.1790423277350827,1.8775608468012885,-0.5968579512594566,1.6409002994968682,-0.3337570158659335,-0.5968579512594566,-0.5292875863064875,2.301101464563815,3.308198222205599,1.7694486191853893,-1.3786049993712943,-1.3786049993712943,0.21636733085825482,0.10863077097339395,4.132037847844936,0.9409952878769652,-1.6685111568748416,3.0017959971834336,0.7920526088666452,-0.0031371136066703498,-0.5629231723307153,-0.9898877670258749,0.5655044371788908,0.053269504024264246,1.41943529737493,0.42084065117869884,0.5180573956646057,-0.30221572716540523,0.08107837999042887,0.21636733085825482
3,193
Endocytosis
41
118
2.489577
0.01279
Q9NVZ3,O95782,O00429,Q9H4M9,Q8WTV0,O43426,Q08380,O60749,P22681,A0FGR8,Q13432,Q9UL25,P62820,P50897,Q9UKG1,Q9H223,Q9UHD9,Q9UBF8,O60784,P50570,Q14108,Q9UQ16,P57105,O15260,P62993,Q5VW38,Q13464,Q99816,O15118,Q5KU26,Q9Y5X3,Q7Z6M1,O15126,Q15036,Q9NX40,Q9Y2T2,Q9P2D3,Q14457,Q9UNF0,P41440,P02786
Processes and pathways
GO Biological process
msigdb_gobp
524,627,505,546,18,650,535,274,780,772,31,299,532,37,569,567,704,432,420,559,51,838,317,804,440,65,687,739,208,342,872,217,594,367,373,503,250,493,391,243,749
772,1241,1761,505,1122,1480,208,594,804,650,1958,274,420,2540,2309,2059,627,749,1720,1441,1864,1769,1162,845,2830,2063,2995,1570,998,1773,780,2234,2399,1168,1260,243,1170,1394,2431,559,37,1396,1629,1869,1497,1731,317,1356,1871,1921,1398,532,440,2370,2626,1687,1635,1734,1785,1359,3105,535,31,687,2128,2374,51,2942,1833,493,970,1453,367,1322,2712,2714,1882,2288,342,1740,65,1219,2809,217,1593,2091,2092,18,1890,1846,980,2142,1142,739,3058,567,1376,546,524,373,250,1151,1292,432,704,1710,2151,569,299,2390,1472,391,838,503,903,1029,872,2462
0.5180573956646057,0.21636733085825482,-0.08979570423491805,0.7480967979523666,0.29469410743066005,0.08107837999042887,1.2182943630695027,0.6581956434453833,0.4940482237889104,0.612209574085093,-0.20938691832830006,1.063003214209736,0.856796727704752,-0.6656250951850902,-0.462913985518726,-0.2709736160130218,0.6352911062035237,0.5418751241716249,-0.0606293056858646,0.10863077097339395,-0.14899690656748693,-0.08979570423491805,0.26881271098746073,0.4698445071041799,-1.0274130001280428,-0.2709736160130218,-1.3786049993712943,0.025199324650836994,0.3710194511388473,-0.08979570423491805,0.5180573956646057,-0.3977371338220593,-0.5292875863064875,0.26881271098746073,0.21636733085825482,1.1221876398575348,0.26881271098746073,0.13593136335059053,-0.5629231723307153,0.7034844439548688,2.8414299150165303,0.13593136335059053,-0.0031371136066703498,-0.14899690656748693,0.08107837999042887,-0.0606293056858646,1.0026222188239642,0.16298471623624555,-0.14899690656748693,-0.1790423277350827,0.13593136335059053,0.7258739119100094,0.8353709145003145,-0.49595119132772597,-0.7355890326334656,-0.031744908526115174,-0.0031371136066703498,-0.0606293056858646,-0.08979570423491805,0.16298471623624555,-1.8407550802597537,0.7258739119100094,2.9809050828258044,0.5889482912953588,-0.30221572716540523,-0.49595119132772597,2.391845426042903,-1.2195274337089115,-0.11924966294507812,0.7701555617414707,0.39603391908014063,0.10863077097339395,0.9201671263885668,0.18979526604543842,-0.8427789578797747,-0.8427789578797747,-0.14899690656748693,-0.4301759669868179,0.9616792082789943,-0.0606293056858646,2.193900422541388,0.2427051145911597,-0.9898877670258749,1.1993188415722877,0.025199324650836994,-0.2709736160130218,-0.2709736160130218,3.4188452578218076,-0.14899690656748693,-0.11924966294507812,0.39603391908014063,-0.30221572716540523,0.29469410743066005,0.5655044371788908,-1.5841846451243686,0.7034844439548688,0.16298471623624555,0.7258739119100094,0.7480967979523666,0.9201671263885668,1.1221876398575348,0.29469410743066005,0.21636733085825482,0.856796727704752,0.5889482912953588,-0.031744908526115174,-0.30221572716540523,0.7034844439548688,1.0430115443451933,-0.49595119132772597,0.10863077097339395,0.8991926986389834,0.4940482237889104,0.7701555617414707,0.44544306819693447,0.3710194511388473,0.4698445071041799,-0.5629231723307153
3,193
Epithelial cell proliferation
10
42
2.484919
0.012958
P09429,Q86VI3,Q9NQC3,P09601,P26583,Q8WTV0,Q9H2J4,Q12959,P57105,P06400
Processes and pathways
GO Biological process
msigdb_gobp
312,296,195,7,107,18,248,121,317,277
1030,2270,1563,1670,1817,2853,277,312,7,349,2830,1771,2779,107,1168,720,1040,1493,317,963,1356,1006,1634,534,2200,2437,121,2709,2756,1739,2177,2630,296,18,1461,1649,2450,1414,248,195,984,1860
0.34579373996602075,-0.4301759669868179,0.025199324650836994,-0.031744908526115174,-0.11924966294507812,-1.065237448909853,1.063003214209736,1.0026222188239642,4.132037847844936,0.9409952878769652,-1.0274130001280428,-0.08979570423491805,-0.9526617479367557,1.7536794627358119,0.26881271098746073,0.5655044371788908,0.34579373996602075,0.08107837999042887,1.0026222188239642,0.39603391908014063,0.16298471623624555,0.3710194511388473,-0.0031371136066703498,0.7258739119100094,-0.3655974840969154,-0.5629231723307153,1.6409002994968682,-0.8427789578797747,-0.9157349411807121,-0.0606293056858646,-0.3337570158659335,-0.7355890326334656,1.0430115443451933,3.4188452578218076,0.10863077097339395,-0.0031371136066703498,-0.5629231723307153,0.13593136335059053,1.1221876398575348,1.2930133010682965,0.39603391908014063,-0.11924966294507812
3,193
Transcriptional regulation by runx2
16
51
2.482367
0.013051
P51665,Q14997,P49721,P28074,P61289,P06493,O43242,P14635,P28072,P25787,P28070,P11802,O00231,P06400,P60900,P20618
Processes and pathways
Reactome Pathways
msigdb_reactome
352,167,8,105,478,236,417,209,20,119,55,215,525,277,30,95
525,2356,1907,2050,1993,417,913,277,236,2731,215,209,1916,95,2467,119,2162,2468,2234,2400,55,20,105,1168,529,2996,1493,2998,1261,1446,8,352,3068,30,478,1631,2434,2802,1266,729,1545,1639,1584,167,929,2449,795,2143,1523,3089,1295
0.7258739119100094,-0.49595119132772597,-0.1790423277350827,-0.2709736160130218,-0.24003068040751657,0.856796727704752,0.42084065117869884,1.063003214209736,1.1416579910536835,-0.8791073450641793,1.1993188415722877,1.2182943630695027,-0.1790423277350827,1.8775608468012885,-0.5968579512594566,1.6409002994968682,-0.3337570158659335,-0.5968579512594566,-0.3977371338220593,-0.5292875863064875,2.301101464563815,3.308198222205599,1.7694486191853893,0.26881271098746073,0.7258739119100094,-1.3786049993712943,0.08107837999042887,-1.3786049993712943,0.21636733085825482,0.10863077097339395,4.132037847844936,0.9409952878769652,-1.6685111568748416,3.0017959971834336,0.7920526088666452,-0.0031371136066703498,-0.5629231723307153,-0.9898877670258749,0.21636733085825482,0.5655044371788908,0.053269504024264246,-0.0031371136066703498,0.025199324650836994,1.41943529737493,0.42084065117869884,-0.5629231723307153,0.5180573956646057,-0.30221572716540523,0.08107837999042887,-1.7540346313524435,0.21636733085825482
3,193
Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1
15
51
2.478657
0.013188
P51665,Q14997,P49721,P28074,P61289,Q9H1A4,Q16763,Q12834,O43242,P28072,P25787,P28070,P06400,P60900,P20618
Processes and pathways
Reactome Pathways
msigdb_reactome
352,167,8,105,478,522,368,457,417,20,119,55,277,30,95
525,2356,1907,2050,1993,2422,417,913,277,1916,95,2467,119,2162,2468,2400,55,20,105,1865,2996,2998,1261,1446,8,352,723,3068,30,478,1631,2434,2802,729,457,1008,1545,1639,167,929,368,2297,795,2143,522,2109,1807,1522,2537,1523,1295
0.7258739119100094,-0.49595119132772597,-0.1790423277350827,-0.2709736160130218,-0.24003068040751657,-0.5629231723307153,0.856796727704752,0.42084065117869884,1.063003214209736,-0.1790423277350827,1.8775608468012885,-0.5968579512594566,1.6409002994968682,-0.3337570158659335,-0.5968579512594566,-0.5292875863064875,2.301101464563815,3.308198222205599,1.7694486191853893,-0.14899690656748693,-1.3786049993712943,-1.3786049993712943,0.21636733085825482,0.10863077097339395,4.132037847844936,0.9409952878769652,0.5655044371788908,-1.6685111568748416,3.0017959971834336,0.7920526088666452,-0.0031371136066703498,-0.5629231723307153,-0.9898877670258749,0.5655044371788908,0.813790292416791,0.3710194511388473,0.053269504024264246,-0.0031371136066703498,1.41943529737493,0.42084065117869884,0.9201671263885668,-0.4301759669868179,0.5180573956646057,-0.30221572716540523,0.7480967979523666,-0.2709736160130218,-0.08979570423491805,0.08107837999042887,-0.631091924935383,0.08107837999042887,0.21636733085825482
3,193
Endothelial cell migration
8
35
2.476798
0.013257
P09429,P14923,P09601,P42785,Q8WTV0,P57105,P04792,Q4VCS5
Processes and pathways
GO Biological process
msigdb_gobp
312,290,7,9,18,317,185,28
1122,1030,572,2795,1563,625,1567,185,1441,1962,1348,312,7,290,1771,2779,2547,1260,1493,9,922,2737,2780,317,1500,340,3027,635,28,2288,18,942,3071,2148,1947
0.29469410743066005,0.34579373996602075,0.680925878721421,-0.9898877670258749,0.025199324650836994,0.6352911062035237,0.025199324650836994,1.3296832447901088,0.10863077097339395,-0.20938691832830006,0.16298471623624555,1.0026222188239642,4.132037847844936,1.0430115443451933,-0.08979570423491805,-0.9526617479367557,-0.6656250951850902,0.21636733085825482,0.08107837999042887,4.117747886511145,0.42084065117869884,-0.8791073450641793,-0.9526617479367557,1.0026222188239642,0.08107837999042887,0.9616792082789943,-1.459939156603208,0.6352911062035237,3.0328607875428633,-0.4301759669868179,3.4188452578218076,0.42084065117869884,-1.6685111568748416,-0.30221572716540523,-0.1790423277350827
3,193
Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen
10
32
2.471695
0.013447
Q15800,Q32P28,O15460,P30519,P09601,P13674,O75592,Q8NB78,Q6UW02,Q16850
Functions
GO Molecular function
msigdb_gomf
381,132,375,6,7,199,451,279,442,93
2421,506,375,1960,2113,451,1564,1253,1486,7,199,2507,6,807,655,2242,2861,1320,381,93,132,1219,1366,442,856,1183,279,2947,2531,2492,1473,2538
-0.5629231723307153,0.7480967979523666,0.8991926986389834,-0.20938691832830006,-0.30221572716540523,0.813790292416791,0.025199324650836994,0.21636733085825482,0.08107837999042887,4.132037847844936,1.2558874980500507,-0.631091924935383,4.195509236421808,0.4940482237889104,0.612209574085093,-0.3977371338220593,-1.065237448909853,0.18979526604543842,0.8991926986389834,1.9077445032407137,1.574489660490009,0.2427051145911597,0.16298471623624555,0.8353709145003145,0.4698445071041799,0.26881271098746073,1.063003214209736,-1.2195274337089115,-0.631091924935383,-0.5968579512594566,0.10863077097339395,-0.631091924935383
3,193
Abnormality of exocrine pancreas physiology
9
21
2.468552
0.013566
Q9UKG1,P09601,Q9UHX1,Q9UJW0,Q15904,P48506,Q8IWV7,P14174,O00330
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
569,7,135,240,460,578,495,242,486
486,2773,7,242,2366,1574,1040,1209,578,1173,2197,460,636,1841,495,2210,135,240,569,1617,1475
0.7701555617414707,-0.9526617479367557,4.132037847844936,1.1221876398575348,-0.49595119132772597,0.025199324650836994,0.34579373996602075,0.2427051145911597,0.680925878721421,0.26881271098746073,-0.3655974840969154,0.813790292416791,0.6352911062035237,-0.11924966294507812,0.7701555617414707,-0.3655974840969154,1.574489660490009,1.1416579910536835,0.7034844439548688,0.025199324650836994,0.10863077097339395
3,193
Disproportionate short limb short stature
12
24
2.467214
0.013617
P42345,Q6DKJ4,Q32P28,Q03164,Q8WVQ1,Q15392,Q9UBM7,Q14739,Q9BV10,Q7LGA3,Q8WTW3,O75718
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
530,516,132,68,332,70,141,175,115,637,245,394
1156,1031,2822,394,676,2937,530,1094,68,1736,1977,175,1879,70,132,516,637,1369,245,332,1464,2528,115,141
0.26881271098746073,0.34579373996602075,-1.0274130001280428,0.8780699365084367,0.5889482912953588,-1.2195274337089115,0.7258739119100094,0.3203531886001632,2.1802255667070183,-0.0606293056858646,-0.20938691832830006,1.3659083845750073,-0.14899690656748693,2.1802255667070183,1.574489660490009,0.7480967979523666,0.6352911062035237,0.16298471623624555,1.1221876398575348,0.9822208710006587,0.10863077097339395,-0.631091924935383,1.6735598720423626,1.5576536448951719
3,193
Cation transmembrane transport
18
118
2.465701
0.013675
Q7KZN9,P78417,Q12959,P62942,Q9Y6M7,P13073,Q9Y619,Q9UDW1,Q96ES6,P42858,Q9H936,O95202,Q9HC21,O75964,Q8TAD4,O43772,Q70HW3,P21796
Processes and pathways
GO Biological process
msigdb_gobp
192,1,121,148,102,253,72,59,12,155,78,262,112,81,280,23,88,26
1762,1763,1247,23,1716,673,1344,2674,3084,2613,81,262,1817,959,2991,2644,1720,1161,1441,1962,1864,2231,2969,2061,651,2115,1087,527,253,1821,2063,1771,2647,1166,3009,2649,2545,26,554,2779,577,3034,2957,2508,1866,1723,1208,2959,155,1394,1395,1093,2701,559,1869,2369,1211,1827,1355,2554,2074,1045,148,1,3026,1733,1687,1874,1359,1688,2438,121,458,2656,1268,2865,1504,2712,1835,1589,88,192,2810,1105,2898,2961,2599,280,587,1113,12,2411,2605,1372,2946,1414,465,1894,2575,698,2768,1190,1852,78,1234,469,112,483,2847,1290,59,1340,1710,1558,310,1905,72,102
-0.08979570423491805,-0.08979570423491805,0.21636733085825482,3.222435477932678,-0.0606293056858646,0.5889482912953588,0.16298471623624555,-0.8067497779060742,-1.7540346313524435,-0.7355890326334656,2.025517574520846,1.0828619555333547,-0.11924966294507812,0.39603391908014063,-1.3786049993712943,-0.7710198034073763,-0.0606293056858646,0.26881271098746073,0.10863077097339395,-0.20938691832830006,-0.14899690656748693,-0.3977371338220593,-1.2984677625692256,-0.2709736160130218,0.612209574085093,-0.30221572716540523,0.3203531886001632,0.7258739119100094,1.102589523776575,-0.11924966294507812,-0.2709736160130218,-0.08979570423491805,-0.7710198034073763,0.26881271098746073,-1.419122462160247,-0.7710198034073763,-0.6656250951850902,3.0940370861233606,0.7034844439548688,-0.9526617479367557,0.680925878721421,-1.5010550842325505,-1.258847985434175,-0.631091924935383,-0.14899690656748693,-0.0606293056858646,0.2427051145911597,-1.258847985434175,1.4720196860623391,0.13593136335059053,0.13593136335059053,0.3203531886001632,-0.8427789578797747,0.7034844439548688,-0.14899690656748693,-0.49595119132772597,0.2427051145911597,-0.11924966294507812,0.16298471623624555,-0.6656250951850902,-0.2709736160130218,0.34579373996602075,1.5065684931882488,5.401623940688195,-1.459939156603208,-0.0606293056858646,-0.031744908526115174,-0.14899690656748693,0.16298471623624555,-0.031744908526115174,-0.5629231723307153,1.6409002994968682,0.813790292416791,-0.7710198034073763,0.21636733085825482,-1.065237448909853,0.08107837999042887,-0.8427789578797747,-0.11924966294507812,0.025199324650836994,1.9524555180193348,1.2930133010682965,-0.9898877670258749,0.3203531886001632,-1.103361115024735,-1.258847985434175,-0.7004574638193659,1.063003214209736,0.680925878721421,0.3203531886001632,3.985962658179109,-0.5292875863064875,-0.7004574638193659,0.16298471623624555,-1.2195274337089115,0.13593136335059053,0.813790292416791,-0.14899690656748693,-0.6656250951850902,0.5889482912953588,-0.9157349411807121,0.26881271098746073,-0.11924966294507812,2.068511822464931,0.2427051145911597,0.813790292416791,1.7058661157411827,0.7920526088666452,-1.0274130001280428,0.21636733085825482,2.2746598733113577,0.18979526604543842,-0.031744908526115174,0.053269504024264246,1.0228851550061475,-0.14899690656748693,2.166487793701175,1.8007392900685555
3,193
Synaptic vesicle localization
8
13
2.462194
0.013809
O00203,O95295,Q9Y2T2,P50570,O14617,P78537,O43426,Q96A57
Processes and pathways
GO Biological process
msigdb_gobp
472,347,503,559,415,680,650,319
472,415,650,347,1164,1572,720,559,680,1687,2128,319,503
0.7920526088666452,0.856796727704752,0.612209574085093,0.9409952878769652,0.26881271098746073,0.025199324650836994,0.5655044371788908,0.7034844439548688,0.5889482912953588,-0.031744908526115174,-0.30221572716540523,1.0026222188239642,0.7701555617414707
3,193
Proteasome
12
36
2.461634
0.013831
P51665,Q14997,P49721,P28074,P61289,Q9Y244,O43242,P28072,P25787,P28070,P60900,P20618
Processes and pathways
KEGG Pathways
msigdb_kegg
352,167,8,105,478,502,417,20,119,55,30,95
525,2356,2050,1993,417,1916,95,2467,119,2162,2468,2400,55,20,105,2996,2998,1261,1446,8,352,3068,30,478,1631,2434,2802,729,1545,167,929,795,2143,1523,1295,502
0.7258739119100094,-0.49595119132772597,-0.2709736160130218,-0.24003068040751657,0.856796727704752,-0.1790423277350827,1.8775608468012885,-0.5968579512594566,1.6409002994968682,-0.3337570158659335,-0.5968579512594566,-0.5292875863064875,2.301101464563815,3.308198222205599,1.7694486191853893,-1.3786049993712943,-1.3786049993712943,0.21636733085825482,0.10863077097339395,4.132037847844936,0.9409952878769652,-1.6685111568748416,3.0017959971834336,0.7920526088666452,-0.0031371136066703498,-0.5629231723307153,-0.9898877670258749,0.5655044371788908,0.053269504024264246,1.41943529737493,0.42084065117869884,0.5180573956646057,-0.30221572716540523,0.08107837999042887,0.21636733085825482,0.7701555617414707
3,193
Degradation of dvl
7
38
2.461608
0.013832
P49721,P28074,P28072,P25787,P28070,P60900,P20618
Processes and pathways
Reactome Pathways
msigdb_reactome
8,105,20,119,55,30,95
525,2356,1907,2050,1993,417,913,1916,95,2467,119,2162,2468,2400,55,20,105,2996,2998,1261,1446,8,352,3068,30,478,1631,2434,2802,729,1545,1048,167,929,795,2143,1523,1295
0.7258739119100094,-0.49595119132772597,-0.1790423277350827,-0.2709736160130218,-0.24003068040751657,0.856796727704752,0.42084065117869884,-0.1790423277350827,1.8775608468012885,-0.5968579512594566,1.6409002994968682,-0.3337570158659335,-0.5968579512594566,-0.5292875863064875,2.301101464563815,3.308198222205599,1.7694486191853893,-1.3786049993712943,-1.3786049993712943,0.21636733085825482,0.10863077097339395,4.132037847844936,0.9409952878769652,-1.6685111568748416,3.0017959971834336,0.7920526088666452,-0.0031371136066703498,-0.5629231723307153,-0.9898877670258749,0.5655044371788908,0.053269504024264246,0.34579373996602075,1.41943529737493,0.42084065117869884,0.5180573956646057,-0.30221572716540523,0.08107837999042887,0.21636733085825482
3,193
Regulation of ras by gaps
7
38
2.461608
0.013832
P49721,P28074,P28072,P25787,P28070,P60900,P20618
Processes and pathways
Reactome Pathways
msigdb_reactome
8,105,20,119,55,30,95
525,2356,1907,2050,1993,417,913,1916,95,2467,119,2162,2468,2400,55,20,105,2996,2998,1261,1446,8,352,3068,30,478,1631,2434,2802,729,1545,1048,167,929,795,2143,1523,1295
0.7258739119100094,-0.49595119132772597,-0.1790423277350827,-0.2709736160130218,-0.24003068040751657,0.856796727704752,0.42084065117869884,-0.1790423277350827,1.8775608468012885,-0.5968579512594566,1.6409002994968682,-0.3337570158659335,-0.5968579512594566,-0.5292875863064875,2.301101464563815,3.308198222205599,1.7694486191853893,-1.3786049993712943,-1.3786049993712943,0.21636733085825482,0.10863077097339395,4.132037847844936,0.9409952878769652,-1.6685111568748416,3.0017959971834336,0.7920526088666452,-0.0031371136066703498,-0.5629231723307153,-0.9898877670258749,0.5655044371788908,0.053269504024264246,0.34579373996602075,1.41943529737493,0.42084065117869884,0.5180573956646057,-0.30221572716540523,0.08107837999042887,0.21636733085825482
3,193
Vitamin metabolic process
9
29
2.453053
0.014165
P09455,P78417,Q9H2D1,Q9NRN7,P00374,Q99707,Q9HC21,P41440,P04062
Processes and pathways
GO Biological process
msigdb_gobp
128,1,35,239,14,308,112,243,158
1815,1670,14,158,128,2695,2364,2003,3169,1259,337,2938,1091,243,578,629,1,2340,1647,1226,1282,2976,1284,942,308,35,112,239,3143
-0.11924966294507812,-0.031744908526115174,3.902465612713916,1.4545942332074184,1.6078795867372875,-0.8427789578797747,-0.49595119132772597,-0.24003068040751657,-2.9747685245557376,0.21636733085825482,0.9616792082789943,-1.2195274337089115,0.3203531886001632,1.1221876398575348,0.680925878721421,0.6352911062035237,5.401623940688195,-0.462913985518726,-0.0031371136066703498,0.2427051145911597,0.21636733085825482,-1.2984677625692256,0.21636733085825482,0.42084065117869884,1.0228851550061475,2.863316355216428,1.7058661157411827,1.1416579910536835,-2.2458099647275738
3,193
Sterol biosynthetic process
6
24
2.450625
0.014261
P48449,Q15392,Q9UBM7,Q9UKR5,P42765,Q16850
Processes and pathways
GO Biological process
msigdb_gobp
99,70,141,143,61,93
1564,2729,3092,507,1087,2397,2507,1573,61,99,1782,2511,2516,1641,1320,175,1879,1834,70,1880,381,93,141,143
0.025199324650836994,-0.8791073450641793,-1.7972452332773272,0.7480967979523666,0.3203531886001632,-0.5292875863064875,-0.631091924935383,0.025199324650836994,2.2345531829313767,1.8317054739763257,-0.08979570423491805,-0.631091924935383,-0.631091924935383,-0.0031371136066703498,0.18979526604543842,1.3659083845750073,-0.14899690656748693,-0.11924966294507812,2.1802255667070183,-0.14899690656748693,0.8991926986389834,1.9077445032407137,1.5576536448951719,1.5407221737348815
3,193
Degradation of gli1 by the proteasome
7
40
2.449583
0.014302
P49721,P28074,P28072,P25787,P28070,P60900,P20618
Processes and pathways
Reactome Pathways
msigdb_reactome
8,105,20,119,55,30,95
525,2356,1907,2050,1993,417,913,1916,95,2467,119,2162,2468,2400,55,20,105,2996,2998,1261,1446,8,352,3068,30,478,1631,2434,2802,1266,729,1545,1584,167,929,2298,795,2143,1523,1295
0.7258739119100094,-0.49595119132772597,-0.1790423277350827,-0.2709736160130218,-0.24003068040751657,0.856796727704752,0.42084065117869884,-0.1790423277350827,1.8775608468012885,-0.5968579512594566,1.6409002994968682,-0.3337570158659335,-0.5968579512594566,-0.5292875863064875,2.301101464563815,3.308198222205599,1.7694486191853893,-1.3786049993712943,-1.3786049993712943,0.21636733085825482,0.10863077097339395,4.132037847844936,0.9409952878769652,-1.6685111568748416,3.0017959971834336,0.7920526088666452,-0.0031371136066703498,-0.5629231723307153,-0.9898877670258749,0.21636733085825482,0.5655044371788908,0.053269504024264246,0.025199324650836994,1.41943529737493,0.42084065117869884,-0.4301759669868179,0.5180573956646057,-0.30221572716540523,0.08107837999042887,0.21636733085825482
3,193
Auf1 hnrnp d0 binds and destabilizes mrna
8
42
2.445032
0.014484
Q14997,P49721,P28074,P28072,P25787,P28070,P60900,P20618
Processes and pathways
Reactome Pathways
msigdb_reactome
167,8,105,20,119,55,30,95
525,2356,1907,2050,1993,417,913,185,1255,918,1916,95,2467,119,2162,2468,2400,55,20,105,2996,2998,1261,1446,8,352,3068,30,478,1631,2434,2802,492,729,1545,2172,167,929,795,2143,1523,1295
0.7258739119100094,-0.49595119132772597,-0.1790423277350827,-0.2709736160130218,-0.24003068040751657,0.856796727704752,0.42084065117869884,1.3296832447901088,0.21636733085825482,0.42084065117869884,-0.1790423277350827,1.8775608468012885,-0.5968579512594566,1.6409002994968682,-0.3337570158659335,-0.5968579512594566,-0.5292875863064875,2.301101464563815,3.308198222205599,1.7694486191853893,-1.3786049993712943,-1.3786049993712943,0.21636733085825482,0.10863077097339395,4.132037847844936,0.9409952878769652,-1.6685111568748416,3.0017959971834336,0.7920526088666452,-0.0031371136066703498,-0.5629231723307153,-0.9898877670258749,0.7701555617414707,0.5655044371788908,0.053269504024264246,-0.3337570158659335,1.41943529737493,0.42084065117869884,0.5180573956646057,-0.30221572716540523,0.08107837999042887,0.21636733085825482
3,193
Tnfr2 non canonical nf kb pathway
7
42
2.44268
0.014579
P49721,P28074,P28072,P25787,P28070,P60900,P20618
Processes and pathways
Reactome Pathways
msigdb_reactome
8,105,20,119,55,30,95
525,2356,1907,2050,1993,989,417,913,1916,95,2467,119,2162,2468,2400,55,20,105,2996,2998,1261,1446,8,352,3068,30,1212,478,1631,2434,2802,1266,729,1545,1584,167,929,1889,795,2143,1523,1295
0.7258739119100094,-0.49595119132772597,-0.1790423277350827,-0.2709736160130218,-0.24003068040751657,0.3710194511388473,0.856796727704752,0.42084065117869884,-0.1790423277350827,1.8775608468012885,-0.5968579512594566,1.6409002994968682,-0.3337570158659335,-0.5968579512594566,-0.5292875863064875,2.301101464563815,3.308198222205599,1.7694486191853893,-1.3786049993712943,-1.3786049993712943,0.21636733085825482,0.10863077097339395,4.132037847844936,0.9409952878769652,-1.6685111568748416,3.0017959971834336,0.2427051145911597,0.7920526088666452,-0.0031371136066703498,-0.5629231723307153,-0.9898877670258749,0.21636733085825482,0.5655044371788908,0.053269504024264246,0.025199324650836994,1.41943529737493,0.42084065117869884,-0.14899690656748693,0.5180573956646057,-0.30221572716540523,0.08107837999042887,0.21636733085825482
3,193
Metabolism of polyamines
7
39
2.436991
0.01481
P49721,P28074,P28072,P25787,P28070,P60900,P20618
Processes and pathways
Reactome Pathways
msigdb_reactome
8,105,20,119,55,30,95
525,2356,1907,2050,1993,417,913,1916,1966,95,2467,119,2162,2468,2400,55,20,105,2996,2998,1261,1446,8,352,2281,3068,30,478,1631,2434,2802,729,1545,167,929,795,2143,1523,1295
0.7258739119100094,-0.49595119132772597,-0.1790423277350827,-0.2709736160130218,-0.24003068040751657,0.856796727704752,0.42084065117869884,-0.1790423277350827,-0.20938691832830006,1.8775608468012885,-0.5968579512594566,1.6409002994968682,-0.3337570158659335,-0.5968579512594566,-0.5292875863064875,2.301101464563815,3.308198222205599,1.7694486191853893,-1.3786049993712943,-1.3786049993712943,0.21636733085825482,0.10863077097339395,4.132037847844936,0.9409952878769652,-0.4301759669868179,-1.6685111568748416,3.0017959971834336,0.7920526088666452,-0.0031371136066703498,-0.5629231723307153,-0.9898877670258749,0.5655044371788908,0.053269504024264246,1.41943529737493,0.42084065117869884,0.5180573956646057,-0.30221572716540523,0.08107837999042887,0.21636733085825482
3,193
Cytochrome complex assembly
6
13
2.429045
0.015139
Q7KZN9,Q9BSK2,Q15070,Q69YU5,Q6DKK2,Q9Y2R0
Processes and pathways
GO Biological process
msigdb_gobp
192,255,326,138,172,116
1766,2360,1093,363,326,138,172,192,860,2575,255,1198,116
-0.08979570423491805,-0.49595119132772597,0.3203531886001632,0.9201671263885668,0.9822208710006587,1.5576536448951719,1.383857498630824,1.2930133010682965,0.4698445071041799,-0.6656250951850902,1.102589523776575,0.26881271098746073,1.6735598720423626
3,193
Regulation of runx3 expression and activity
6
37
2.427246
0.015214
P49721,P28074,P28072,P28070,P60900,P20618
Processes and pathways
Reactome Pathways
msigdb_reactome
8,105,20,55,30,95
525,2356,1907,2050,1993,417,913,1916,95,2467,119,2162,2468,2400,55,20,105,2996,1209,2998,1261,1446,8,352,3068,30,478,1631,2434,2802,729,1545,929,795,2143,1523,1295
0.7258739119100094,-0.49595119132772597,-0.1790423277350827,-0.2709736160130218,-0.24003068040751657,0.856796727704752,0.42084065117869884,-0.1790423277350827,1.8775608468012885,-0.5968579512594566,1.6409002994968682,-0.3337570158659335,-0.5968579512594566,-0.5292875863064875,2.301101464563815,3.308198222205599,1.7694486191853893,-1.3786049993712943,0.2427051145911597,-1.3786049993712943,0.21636733085825482,0.10863077097339395,4.132037847844936,0.9409952878769652,-1.6685111568748416,3.0017959971834336,0.7920526088666452,-0.0031371136066703498,-0.5629231723307153,-0.9898877670258749,0.5655044371788908,0.053269504024264246,0.42084065117869884,0.5180573956646057,-0.30221572716540523,0.08107837999042887,0.21636733085825482
3,193
Cytosolic transport
40
66
2.426648
0.015239
O95782,O60499,Q96QK1,P53367,Q9UID3,Q9C0C9,Q4KMP7,O60493,P35241,O60749,Q4J6C6,Q9UL25,O60271,O15498,P42566,P28482,O94832,O75503,Q99570,O15260,Q8IWJ2,P49257,Q7Z3U7,Q9Y5X3,P61106,Q8IUD2,O75436,P15311,Q13190,Q9H3S7,Q96RL7,P40616,Q9P2R3,Q14457,Q9P2D3,Q8N2H4,Q14203,P26038,Q9UNK0,P20339
Processes and pathways
GO Biological process
msigdb_gobp
627,376,1185,137,801,1067,541,774,396,274,1055,299,907,286,1170,1168,675,184,1230,804,462,961,210,872,965,357,843,845,226,1145,497,488,1151,493,250,1136,758,1126,124,998
1714,1480,804,286,1958,907,774,376,274,2540,843,2497,184,675,1386,627,1915,845,998,2545,1126,2234,1168,1572,396,2068,488,1170,961,1629,137,2654,965,2885,1635,2200,1360,226,2374,758,493,1322,1055,541,210,357,462,1136,1699,1892,1185,497,1230,2349,1067,1145,2458,250,1151,1660,801,1856,299,1237,124,872
-0.0606293056858646,0.08107837999042887,0.4940482237889104,1.0430115443451933,-0.20938691832830006,0.42084065117869884,0.5180573956646057,0.8991926986389834,1.063003214209736,-0.6656250951850902,0.4698445071041799,-0.631091924935383,1.3296832447901088,0.5889482912953588,0.13593136335059053,0.6352911062035237,-0.1790423277350827,0.4698445071041799,0.3710194511388473,-0.6656250951850902,0.29469410743066005,-0.3977371338220593,0.26881271098746073,0.025199324650836994,0.8780699365084367,-0.2709736160130218,0.7701555617414707,0.26881271098746073,0.39603391908014063,-0.0031371136066703498,1.5576536448951719,-0.7710198034073763,0.39603391908014063,-1.103361115024735,-0.0031371136066703498,-0.3655974840969154,0.16298471623624555,1.1802219848882647,-0.49595119132772597,0.5418751241716249,0.7701555617414707,0.18979526604543842,0.34579373996602075,0.7258739119100094,1.2182943630695027,0.9409952878769652,0.813790292416791,0.29469410743066005,-0.031744908526115174,-0.14899690656748693,0.26881271098746073,0.7701555617414707,0.2427051145911597,-0.462913985518726,0.34579373996602075,0.29469410743066005,-0.5629231723307153,1.1221876398575348,0.29469410743066005,-0.0031371136066703498,0.5180573956646057,-0.11924966294507812,1.0430115443451933,0.2427051145911597,1.6409002994968682,0.4698445071041799
3,193
Mitochondrion organization
54
189
2.426373
0.015251
Q9BSK2,O00429,O14737,Q69YU5,Q16543,Q96CU9,Q8N4H5,O95202,O60830,Q9NUQ9,Q9NS69,Q7Z3C6,O95429,P21796,O75306,P42858,P04062,Q99595,Q9NVT9,P53365,P45880,Q13505,O14925,P14406,Q16611,Q6DKK2,Q9NQ88,Q96A26,Q9Y6C9,P42765,Q6UXV4,O43676,P17152,Q15070,Q15388,Q04837,Q5JRX3,A6NDU8,Q9UDX5,Q9BWH2,Q5T9A4,P30536,P55786,O00203,Q8IWA4,O75153,Q96RL7,Q9Y2R0,Q8N2A8,Q9P0J0,P30419,Q9GZY8,Q14457,Q9H061
Processes and pathways
GO Biological process
msigdb_gobp
255,505,252,138,266,408,142,262,17,284,24,278,395,26,526,155,158,32,163,164,38,166,169,42,171,172,178,181,182,61,203,73,200,326,205,456,84,449,89,482,354,100,101,472,233,106,497,116,386,249,361,247,493,126
449,1619,1430,472,592,505,252,169,2422,1909,711,73,1766,748,17,106,1483,1344,526,2674,2541,3084,1912,913,2360,2728,2730,1385,262,3055,2642,395,1346,713,1388,914,749,158,2825,2773,1161,915,2363,1390,3041,1204,527,42,200,1165,26,3034,1968,2548,2957,361,100,2618,2426,3035,2010,3118,61,155,38,1093,578,851,961,1129,2591,721,1781,722,2882,164,101,1397,1213,2015,2782,1687,456,855,166,2079,1833,493,326,1324,205,1788,266,171,789,2440,1325,1881,3148,2560,2628,84,354,2023,1838,138,172,203,1458,278,820,1460,233,2915,2563,2443,2444,1106,386,142,2811,2719,3039,2599,2484,1109,2136,587,1936,2032,181,408,2253,1185,497,1373,738,2946,663,32,1414,2764,831,860,2575,255,2977,2870,1467,482,699,247,2454,126,1114,2301,2871,2668,178,1608,24,945,284,1023,1338,163,1339,1900,1291,1150,249,1521,2743,89,1855,984,1558,1198,116,648,2820,1860,1663,1905,1476,2393,802,182,1240
0.813790292416791,-0.0031371136066703498,0.10863077097339395,0.7920526088666452,0.6581956434453833,0.7480967979523666,1.102589523776575,1.383857498630824,-0.5629231723307153,-0.1790423277350827,0.5655044371788908,2.152686522096174,-0.08979570423491805,0.5418751241716249,3.6453743945093926,1.7536794627358119,0.08107837999042887,0.16298471623624555,0.7258739119100094,-0.8067497779060742,-0.6656250951850902,-1.7540346313524435,-0.1790423277350827,0.42084065117869884,-0.49595119132772597,-0.8791073450641793,-0.8791073450641793,0.13593136335059053,1.0828619555333547,-1.5841846451243686,-0.7710198034073763,0.8780699365084367,0.16298471623624555,0.5655044371788908,0.13593136335059053,0.42084065117869884,0.5418751241716249,1.4545942332074184,-1.0274130001280428,-0.9526617479367557,0.26881271098746073,0.42084065117869884,-0.49595119132772597,0.13593136335059053,-1.5424702465695177,0.2427051145911597,0.7258739119100094,2.6013806888194835,1.2558874980500507,0.26881271098746073,3.0940370861233606,-1.5010550842325505,-0.20938691832830006,-0.6656250951850902,-1.258847985434175,0.9201671263885668,1.8007392900685555,-0.7355890326334656,-0.5629231723307153,-1.5010550842325505,-0.24003068040751657,-1.9730801058799055,2.2345531829313767,1.4720196860623391,2.7295242300793277,0.3203531886001632,0.680925878721421,0.4698445071041799,0.39603391908014063,0.29469410743066005,-0.7004574638193659,0.5655044371788908,-0.08979570423491805,0.5655044371788908,-1.103361115024735,1.41943529737493,1.8007392900685555,0.13593136335059053,0.2427051145911597,-0.24003068040751657,-0.9526617479367557,-0.031744908526115174,0.813790292416791,0.4698445071041799,1.41943529737493,-0.2709736160130218,-0.11924966294507812,0.7701555617414707,0.9822208710006587,0.18979526604543842,1.2371500809699392,-0.08979570423491805,1.0828619555333547,1.383857498630824,0.5180573956646057,-0.5629231723307153,0.18979526604543842,-0.14899690656748693,-2.339113975187537,-0.6656250951850902,-0.7355890326334656,2.0110474795908226,0.9409952878769652,-0.24003068040751657,-0.11924966294507812,1.5576536448951719,1.383857498630824,1.2558874980500507,0.10863077097339395,1.063003214209736,0.4940482237889104,0.10863077097339395,1.1610022318711952,-1.1417840001131578,-0.6656250951850902,-0.5629231723307153,-0.5629231723307153,0.3203531886001632,0.8991926986389834,1.5407221737348815,-0.9898877670258749,-0.8427789578797747,-1.5010550842325505,-0.7004574638193659,-0.5968579512594566,0.3203531886001632,-0.30221572716540523,0.680925878721421,-0.1790423277350827,-0.24003068040751657,1.3478507399601813,0.8780699365084367,-0.3977371338220593,0.26881271098746073,0.7701555617414707,0.16298471623624555,0.5655044371788908,-1.2195274337089115,0.612209574085093,2.9598669449402526,0.13593136335059053,-0.9157349411807121,0.4940482237889104,0.4698445071041799,-0.6656250951850902,1.102589523776575,-1.2984677625692256,-1.065237448909853,0.10863077097339395,0.7920526088666452,0.5889482912953588,1.1221876398575348,-0.5629231723307153,1.6244355839494933,0.3203531886001632,-0.4301759669868179,-1.065237448909853,-0.7710198034073763,1.3659083845750073,0.025199324650836994,3.193291468873368,0.42084065117869884,1.063003214209736,0.3710194511388473,0.18979526604543842,1.437066506048789,0.18979526604543842,-0.14899690656748693,0.21636733085825482,0.29469410743066005,1.1221876398575348,0.08107837999042887,-0.8791073450641793,1.9524555180193348,-0.11924966294507812,0.39603391908014063,0.053269504024264246,0.26881271098746073,1.6735598720423626,0.6352911062035237,-0.9898877670258749,-0.11924966294507812,-0.0031371136066703498,-0.14899690656748693,0.10863077097339395,-0.49595119132772597,0.5180573956646057,1.3478507399601813,0.2427051145911597
3,193
Lipid homeostasis
10
24
2.424948
0.015311
P09455,Q9NQC3,P35610,Q86YV9,Q8WTV0,O15118,Q5BJF2,Q9Y6C9,Q9BWH2,P34913
Processes and pathways
GO Biological process
msigdb_gobp
128,195,324,307,18,208,117,182,482,190
2582,208,804,995,128,997,1258,190,324,1131,2862,972,117,1740,1365,307,18,482,546,667,195,1120,2692,182
-0.7004574638193659,1.2182943630695027,0.4940482237889104,0.3710194511388473,1.6078795867372875,0.3710194511388473,0.21636733085825482,1.2930133010682965,0.9822208710006587,0.29469410743066005,-1.065237448909853,0.39603391908014063,1.6572747340816105,-0.0606293056858646,0.16298471623624555,1.0228851550061475,3.4188452578218076,0.7920526088666452,0.7258739119100094,0.612209574085093,1.2930133010682965,0.3203531886001632,-0.8067497779060742,1.3478507399601813
3,193
Mapk6 mapk4 signaling
13
49
2.420749
0.015489
Q9HCE1,P51665,Q14997,P49721,P28074,P06493,O43242,P28072,P25787,P28070,P04792,P60900,P20618
Processes and pathways
Reactome Pathways
msigdb_reactome
298,352,167,8,105,236,417,20,119,55,185,30,95
525,2356,1907,2050,1993,1624,417,913,185,2853,236,1916,95,1167,2467,119,2162,2468,2400,55,20,105,2996,2998,1261,1446,8,352,3068,30,1356,478,1631,2434,2802,729,685,1545,167,929,1363,1409,795,2143,298,1805,1523,1295,707
0.7258739119100094,-0.49595119132772597,-0.1790423277350827,-0.2709736160130218,-0.24003068040751657,-0.0031371136066703498,0.856796727704752,0.42084065117869884,1.3296832447901088,-1.065237448909853,1.1416579910536835,-0.1790423277350827,1.8775608468012885,0.26881271098746073,-0.5968579512594566,1.6409002994968682,-0.3337570158659335,-0.5968579512594566,-0.5292875863064875,2.301101464563815,3.308198222205599,1.7694486191853893,-1.3786049993712943,-1.3786049993712943,0.21636733085825482,0.10863077097339395,4.132037847844936,0.9409952878769652,-1.6685111568748416,3.0017959971834336,0.16298471623624555,0.7920526088666452,-0.0031371136066703498,-0.5629231723307153,-0.9898877670258749,0.5655044371788908,0.5889482912953588,0.053269504024264246,1.41943529737493,0.42084065117869884,0.16298471623624555,0.13593136335059053,0.5180573956646057,-0.30221572716540523,1.0430115443451933,-0.08979570423491805,0.08107837999042887,0.21636733085825482,0.5889482912953588
3,193
Autophagy of mitochondrion
12
34
2.414908
0.015739
O00429,P53365,P30536,Q16543,P42858,Q9NQ88,Q14457,A6NDU8,Q7Z3C6,Q9BWH2,P21796,P04062
Processes and pathways
GO Biological process
msigdb_gobp
505,164,100,266,155,178,493,449,278,482,26,158
449,1619,505,1909,2730,158,2773,1161,527,1165,26,100,155,1129,721,2882,164,1397,1833,493,266,1458,278,1460,2719,2032,2946,1414,482,178,945,1521,984,1663
0.813790292416791,-0.0031371136066703498,0.7480967979523666,-0.1790423277350827,-0.8791073450641793,1.4545942332074184,-0.9526617479367557,0.26881271098746073,0.7258739119100094,0.26881271098746073,3.0940370861233606,1.8007392900685555,1.4720196860623391,0.29469410743066005,0.5655044371788908,-1.103361115024735,1.41943529737493,0.13593136335059053,-0.11924966294507812,0.7701555617414707,1.0828619555333547,0.10863077097339395,1.063003214209736,0.10863077097339395,-0.8427789578797747,-0.24003068040751657,-1.2195274337089115,0.13593136335059053,0.7920526088666452,1.3659083845750073,0.42084065117869884,0.08107837999042887,0.39603391908014063,-0.0031371136066703498
3,193
Runx1 regulates transcription of genes involved in differentiation of hscs
8
42
2.414594
0.015753
Q03164,P49721,P28074,P28072,P25787,P28070,P60900,P20618
Processes and pathways
Reactome Pathways
msigdb_reactome
68,8,105,20,119,55,30,95
525,2356,1907,2050,1993,417,913,3067,1916,95,2467,119,2162,2468,2400,55,20,105,2996,2998,1261,1446,8,352,3068,30,478,1631,2434,2802,2803,1685,68,729,1545,167,929,2298,795,2143,1523,1295
0.7258739119100094,-0.49595119132772597,-0.1790423277350827,-0.2709736160130218,-0.24003068040751657,0.856796727704752,0.42084065117869884,-1.6685111568748416,-0.1790423277350827,1.8775608468012885,-0.5968579512594566,1.6409002994968682,-0.3337570158659335,-0.5968579512594566,-0.5292875863064875,2.301101464563815,3.308198222205599,1.7694486191853893,-1.3786049993712943,-1.3786049993712943,0.21636733085825482,0.10863077097339395,4.132037847844936,0.9409952878769652,-1.6685111568748416,3.0017959971834336,0.7920526088666452,-0.0031371136066703498,-0.5629231723307153,-0.9898877670258749,-0.9898877670258749,-0.031744908526115174,2.1802255667070183,0.5655044371788908,0.053269504024264246,1.41943529737493,0.42084065117869884,-0.4301759669868179,0.5180573956646057,-0.30221572716540523,0.08107837999042887,0.21636733085825482
3,193
Cellular ion homeostasis
22
87
2.414353
0.015763
P78417,P09601,Q8N511,Q92544,O95202,Q9Y487,Q8TAD4,P62942,P42858,P50897,Q16611,Q9UM00,O14617,Q7L0J3,O75503,O76003,P09429,Q9HC07,Q15904,Q9HD20,Q9Y6M7,O95295
Processes and pathways
GO Biological process
msigdb_gobp
1,7,139,407,262,153,280,148,155,37,171,310,415,53,184,187,312,469,460,483,102,347
472,415,1763,1766,1716,672,673,184,2360,187,1767,262,3019,347,749,2991,2644,1720,2114,1962,2645,2969,312,7,2396,2503,1088,2778,1821,2063,1771,2647,576,2234,3034,2547,1168,2508,2959,155,37,1629,1781,1869,2196,2369,1211,2554,1045,148,1,3026,1687,1785,2656,1975,1504,2712,460,171,1881,53,2810,1105,139,2599,280,587,407,793,826,1371,2605,2098,1894,1190,700,469,483,1340,1710,1558,310,153,1905,987,102
0.7920526088666452,0.856796727704752,-0.08979570423491805,-0.08979570423491805,-0.0606293056858646,0.5889482912953588,0.5889482912953588,1.3296832447901088,-0.49595119132772597,1.3114045548408733,-0.08979570423491805,1.0828619555333547,-1.459939156603208,0.9409952878769652,0.5418751241716249,-1.3786049993712943,-0.7710198034073763,-0.0606293056858646,-0.30221572716540523,-0.20938691832830006,-0.7710198034073763,-1.2984677625692256,1.0026222188239642,4.132037847844936,-0.5292875863064875,-0.631091924935383,0.3203531886001632,-0.9526617479367557,-0.11924966294507812,-0.2709736160130218,-0.08979570423491805,-0.7710198034073763,0.680925878721421,-0.3977371338220593,-1.5010550842325505,-0.6656250951850902,0.26881271098746073,-0.631091924935383,-1.258847985434175,1.4720196860623391,2.8414299150165303,-0.0031371136066703498,-0.08979570423491805,-0.14899690656748693,-0.3655974840969154,-0.49595119132772597,0.2427051145911597,-0.6656250951850902,0.34579373996602075,1.5065684931882488,5.401623940688195,-1.459939156603208,-0.031744908526115174,-0.08979570423491805,-0.7710198034073763,-0.20938691832830006,0.08107837999042887,-0.8427789578797747,0.813790292416791,1.383857498630824,-0.14899690656748693,2.3661987741265276,-0.9898877670258749,0.3203531886001632,1.5576536448951719,-0.7004574638193659,1.063003214209736,0.680925878721421,0.8780699365084367,0.5180573956646057,0.4940482237889104,0.16298471623624555,-0.7004574638193659,-0.2709736160130218,-0.14899690656748693,0.26881271098746073,0.5889482912953588,0.813790292416791,0.7920526088666452,0.18979526604543842,-0.031744908526115174,0.053269504024264246,1.0228851550061475,1.5065684931882488,-0.14899690656748693,0.39603391908014063,1.8007392900685555
3,193
Negative regulation of notch4 signaling
6
40
2.411726
0.015877
P49721,P28074,P28072,P28070,P60900,P20618
Processes and pathways
Reactome Pathways
msigdb_reactome
8,105,20,55,30,95
525,2356,1907,2050,1993,417,913,1916,95,2467,119,2162,2468,2400,55,20,105,2996,2998,1261,1446,8,352,3068,30,478,1631,2434,2802,1499,1266,729,1545,1584,929,795,2143,1523,1295,2224
0.7258739119100094,-0.49595119132772597,-0.1790423277350827,-0.2709736160130218,-0.24003068040751657,0.856796727704752,0.42084065117869884,-0.1790423277350827,1.8775608468012885,-0.5968579512594566,1.6409002994968682,-0.3337570158659335,-0.5968579512594566,-0.5292875863064875,2.301101464563815,3.308198222205599,1.7694486191853893,-1.3786049993712943,-1.3786049993712943,0.21636733085825482,0.10863077097339395,4.132037847844936,0.9409952878769652,-1.6685111568748416,3.0017959971834336,0.7920526088666452,-0.0031371136066703498,-0.5629231723307153,-0.9898877670258749,0.08107837999042887,0.21636733085825482,0.5655044371788908,0.053269504024264246,0.025199324650836994,0.42084065117869884,0.5180573956646057,-0.30221572716540523,0.08107837999042887,0.21636733085825482,-0.3655974840969154
3,193
protease
6
41
2.408786
0.016006
P49721,P28074,P28072,P28070,P60900,P20618
Functions
Panther Protein class
panther_protein_class
8,105,20,55,30,95
2356,1907,1993,417,1124,1816,1916,95,2467,119,2162,2468,2400,55,20,105,2996,2012,2998,1261,1446,8,1825,3068,30,1097,1631,2434,2802,1545,1738,1223,795,2143,943,982,944,3081,1295,744,1902
-0.49595119132772597,-0.1790423277350827,-0.24003068040751657,0.856796727704752,0.29469410743066005,-0.11924966294507812,-0.1790423277350827,1.8775608468012885,-0.5968579512594566,1.6409002994968682,-0.3337570158659335,-0.5968579512594566,-0.5292875863064875,2.301101464563815,3.308198222205599,1.7694486191853893,-1.3786049993712943,-0.24003068040751657,-1.3786049993712943,0.21636733085825482,0.10863077097339395,4.132037847844936,-0.11924966294507812,-1.6685111568748416,3.0017959971834336,0.3203531886001632,-0.0031371136066703498,-0.5629231723307153,-0.9898877670258749,0.053269504024264246,-0.0606293056858646,0.2427051145911597,0.5180573956646057,-0.30221572716540523,0.42084065117869884,0.39603391908014063,0.42084065117869884,-1.7111232730375066,0.21636733085825482,0.5655044371788908,-0.14899690656748693
3,193
Entry into host
6
32
2.406951
0.016086
P19474,P06493,O00505,Q8WTV0,Q14108,O15118
Processes and pathways
GO Biological process
msigdb_gobp
43,236,261,18,51,208
261,1030,208,774,749,1441,236,1486,2061,2994,1443,1915,1391,43,780,2426,1000,1170,2432,1829,2015,1689,51,1503,1835,18,1936,2298,1595,320,837,2850
1.0828619555333547,0.34579373996602075,1.2182943630695027,0.5180573956646057,0.5418751241716249,0.10863077097339395,1.1416579910536835,0.08107837999042887,-0.2709736160130218,-1.3786049993712943,0.10863077097339395,-0.1790423277350827,0.13593136335059053,2.6013806888194835,0.5180573956646057,-0.5629231723307153,0.3710194511388473,0.26881271098746073,-0.5629231723307153,-0.11924966294507812,-0.24003068040751657,-0.031744908526115174,2.391845426042903,0.08107837999042887,-0.11924966294507812,3.4188452578218076,-0.1790423277350827,-0.4301759669868179,0.025199324650836994,1.0026222188239642,0.4940482237889104,-1.0274130001280428
3,193
Antigen processing ubiquitination proteasome degradation
22
90
2.40395
0.016219
P49721,P28072,Q9UBS8,P60900,Q14997,P19474,Q9UIQ6,O43242,P28070,Q12834,P61088,P61289,P20618,P51665,P49427,P55786,P28074,Q7Z7E8,Q16763,Q8IWV7,P25787,Q9H1A4
Processes and pathways
Reactome Pathways
msigdb_reactome
8,20,21,30,167,43,47,417,55,457,455,478,95,352,477,101,105,237,368,495,119,522
1952,525,2356,1907,2050,1993,417,913,626,1532,2642,1916,43,95,2735,2467,119,2162,2468,2400,55,20,105,2235,1865,2996,2998,1394,1261,477,1446,8,352,2325,3068,101,30,1212,754,455,478,1631,2434,2802,1266,1213,1785,729,457,1008,1545,1639,1584,603,1048,928,2243,167,929,1693,2627,3099,1407,368,3038,932,761,1460,237,495,1889,792,1113,2298,795,2143,1067,522,799,21,47,2109,1807,1522,2537,1523,1076,3089,1295,902
-0.20938691832830006,0.7258739119100094,-0.49595119132772597,-0.1790423277350827,-0.2709736160130218,-0.24003068040751657,0.856796727704752,0.42084065117869884,0.6352911062035237,0.053269504024264246,-0.7710198034073763,-0.1790423277350827,2.6013806888194835,1.8775608468012885,-0.8791073450641793,-0.5968579512594566,1.6409002994968682,-0.3337570158659335,-0.5968579512594566,-0.5292875863064875,2.301101464563815,3.308198222205599,1.7694486191853893,-0.3977371338220593,-0.14899690656748693,-1.3786049993712943,-1.3786049993712943,0.13593136335059053,0.21636733085825482,0.7920526088666452,0.10863077097339395,4.132037847844936,0.9409952878769652,-0.462913985518726,-1.6685111568748416,1.8007392900685555,3.0017959971834336,0.2427051145911597,0.5418751241716249,0.813790292416791,0.7920526088666452,-0.0031371136066703498,-0.5629231723307153,-0.9898877670258749,0.21636733085825482,0.2427051145911597,-0.08979570423491805,0.5655044371788908,0.813790292416791,0.3710194511388473,0.053269504024264246,-0.0031371136066703498,0.025199324650836994,0.6581956434453833,0.34579373996602075,0.42084065117869884,-0.3977371338220593,1.41943529737493,0.42084065117869884,-0.031744908526115174,-0.7355890326334656,-1.7972452332773272,0.13593136335059053,0.9201671263885668,-1.5010550842325505,0.42084065117869884,0.5418751241716249,0.10863077097339395,1.1416579910536835,0.7701555617414707,-0.14899690656748693,0.5180573956646057,0.3203531886001632,-0.4301759669868179,0.5180573956646057,-0.30221572716540523,0.34579373996602075,0.7480967979523666,0.5180573956646057,3.2893516380101935,2.5046047789471104,-0.2709736160130218,-0.08979570423491805,0.08107837999042887,-0.631091924935383,0.08107837999042887,0.34579373996602075,-1.7540346313524435,0.21636733085825482,0.44544306819693447
3,193
Downstream signaling events of b cell receptor bcr
8
46
2.395327
0.016606
P49721,P28074,P28072,P25787,P28070,P62942,P60900,P20618
Processes and pathways
Reactome Pathways
msigdb_reactome
8,105,20,119,55,148,30,95
525,2356,1907,2050,1993,989,417,913,1387,2114,1916,95,2467,119,2162,2468,2400,55,20,105,2996,2998,1261,1446,8,352,3068,30,478,1631,2434,2802,148,1266,756,729,3105,1545,1584,167,929,795,2143,1523,1295,1760
0.7258739119100094,-0.49595119132772597,-0.1790423277350827,-0.2709736160130218,-0.24003068040751657,0.3710194511388473,0.856796727704752,0.42084065117869884,0.13593136335059053,-0.30221572716540523,-0.1790423277350827,1.8775608468012885,-0.5968579512594566,1.6409002994968682,-0.3337570158659335,-0.5968579512594566,-0.5292875863064875,2.301101464563815,3.308198222205599,1.7694486191853893,-1.3786049993712943,-1.3786049993712943,0.21636733085825482,0.10863077097339395,4.132037847844936,0.9409952878769652,-1.6685111568748416,3.0017959971834336,0.7920526088666452,-0.0031371136066703498,-0.5629231723307153,-0.9898877670258749,1.5065684931882488,0.21636733085825482,0.5418751241716249,0.5655044371788908,-1.8407550802597537,0.053269504024264246,0.025199324650836994,1.41943529737493,0.42084065117869884,0.5180573956646057,-0.30221572716540523,0.08107837999042887,0.21636733085825482,-0.0606293056858646
3,193
Intrinsic component of mitochondrial membrane
13
47
2.39317
0.016703
Q99595,Q13505,Q6UXV4,O14925,P17152,Q16611,Q8IWA4,Q15388,Q9HC21,O60830,Q9Y2R0,Q9GZY8,P57105
Localization
GO Cellular component
msigdb_gocc
32,166,203,169,200,171,233,205,112,17,116,247,317
169,1766,17,2541,2360,2728,2730,1388,527,200,3118,2981,2324,317,1733,166,326,205,819,171,1881,2628,1838,2026,203,233,2915,2563,2599,2032,1372,32,1894,1467,482,247,1114,1234,2667,112,2873,1023,1291,1855,116,1905,1476
1.383857498630824,-0.08979570423491805,3.6453743945093926,-0.6656250951850902,-0.49595119132772597,-0.8791073450641793,-0.8791073450641793,0.13593136335059053,0.7258739119100094,1.2558874980500507,-1.9730801058799055,-1.3383867666926692,-0.462913985518726,1.0026222188239642,-0.0606293056858646,1.41943529737493,0.9822208710006587,1.2371500809699392,0.4940482237889104,1.383857498630824,-0.14899690656748693,-0.7355890326334656,-0.11924966294507812,-0.24003068040751657,1.2558874980500507,1.1610022318711952,-1.1417840001131578,-0.6656250951850902,-0.7004574638193659,-0.24003068040751657,0.16298471623624555,2.9598669449402526,-0.14899690656748693,0.10863077097339395,0.7920526088666452,1.1221876398575348,0.3203531886001632,0.2427051145911597,-0.7710198034073763,1.7058661157411827,-1.065237448909853,0.3710194511388473,0.21636733085825482,-0.11924966294507812,1.6735598720423626,-0.14899690656748693,0.10863077097339395
3,193
Sphingolipid metabolism
9
26
2.391274
0.01679
P07602,Q96G23,P16278,Q06136,Q13510,Q9NZJ7,Q16880,P10619,P04062
Processes and pathways
Reactome Pathways
msigdb_reactome
67,41,263,16,50,321,188,60,158
772,1668,1381,624,3019,574,158,996,1389,67,2645,60,2365,263,350,2318,599,16,50,188,3136,41,2722,1235,321,2691
0.5180573956646057,-0.031744908526115174,0.13593136335059053,0.6352911062035237,-1.459939156603208,0.680925878721421,1.4545942332074184,0.3710194511388473,0.13593136335059053,2.1802255667070183,-0.7710198034073763,2.261350745716217,-0.49595119132772597,1.0828619555333547,0.9409952878769652,-0.462913985518726,0.6581956434453833,3.703535835976282,2.4045866103244666,1.3114045548408733,-2.153702990291578,2.671958061458734,-0.8427789578797747,0.2427051145911597,1.0026222188239642,-0.8067497779060742
3,193
G1 to s cell cycle control
14
27
2.391118
0.016797
P49642,P33991,Q07864,Q13416,Q9Y619,P24941,Q9UBD5,P06493,P14635,O75419,P35244,P11802,P06400,Q14566
Processes and pathways
WikiPathways
msigdb_wp
598,719,225,632,72,422,800,236,209,301,397,215,277,293
906,301,2773,277,236,215,2828,209,1163,422,781,1676,719,1627,1038,397,1209,598,1311,1494,1634,225,632,293,2573,800,72
0.42084065117869884,1.0228851550061475,-0.9526617479367557,1.063003214209736,1.1416579910536835,1.1993188415722877,-1.0274130001280428,1.2182943630695027,0.26881271098746073,0.856796727704752,0.5180573956646057,-0.031744908526115174,0.5655044371788908,-0.0031371136066703498,0.34579373996602075,0.8780699365084367,0.2427051145911597,0.6581956434453833,0.18979526604543842,0.08107837999042887,-0.0031371136066703498,1.1802219848882647,0.6352911062035237,1.0430115443451933,-0.6656250951850902,0.5180573956646057,2.166487793701175
3,193
Dectin 1 mediated noncanonical nf kb signaling
7
43
2.390356
0.016832
P49721,P28074,P28072,P25787,P28070,P60900,P20618
Processes and pathways
Reactome Pathways
msigdb_reactome
8,105,20,119,55,30,95
525,2356,1907,2050,1993,989,417,913,1916,95,2467,119,2162,2468,2400,55,20,105,2996,2998,1261,1446,8,352,3068,30,1212,478,1631,2434,2802,1266,756,729,1545,1584,167,929,1889,795,2143,1523,1295
0.7258739119100094,-0.49595119132772597,-0.1790423277350827,-0.2709736160130218,-0.24003068040751657,0.3710194511388473,0.856796727704752,0.42084065117869884,-0.1790423277350827,1.8775608468012885,-0.5968579512594566,1.6409002994968682,-0.3337570158659335,-0.5968579512594566,-0.5292875863064875,2.301101464563815,3.308198222205599,1.7694486191853893,-1.3786049993712943,-1.3786049993712943,0.21636733085825482,0.10863077097339395,4.132037847844936,0.9409952878769652,-1.6685111568748416,3.0017959971834336,0.2427051145911597,0.7920526088666452,-0.0031371136066703498,-0.5629231723307153,-0.9898877670258749,0.21636733085825482,0.5418751241716249,0.5655044371788908,0.053269504024264246,0.025199324650836994,1.41943529737493,0.42084065117869884,-0.14899690656748693,0.5180573956646057,-0.30221572716540523,0.08107837999042887,0.21636733085825482
3,193
Signaling by notch4
6
42
2.387148
0.01698
P49721,P28074,P28072,P28070,P60900,P20618
Processes and pathways
Reactome Pathways
msigdb_reactome
8,105,20,55,30,95
525,2356,1907,2050,1993,417,913,1916,95,2467,119,2162,2468,2400,55,20,105,2996,2998,1261,1446,8,352,3068,30,478,1631,2434,2802,1499,1266,729,1545,1047,1584,929,1461,795,2143,1523,1295,2224
0.7258739119100094,-0.49595119132772597,-0.1790423277350827,-0.2709736160130218,-0.24003068040751657,0.856796727704752,0.42084065117869884,-0.1790423277350827,1.8775608468012885,-0.5968579512594566,1.6409002994968682,-0.3337570158659335,-0.5968579512594566,-0.5292875863064875,2.301101464563815,3.308198222205599,1.7694486191853893,-1.3786049993712943,-1.3786049993712943,0.21636733085825482,0.10863077097339395,4.132037847844936,0.9409952878769652,-1.6685111568748416,3.0017959971834336,0.7920526088666452,-0.0031371136066703498,-0.5629231723307153,-0.9898877670258749,0.08107837999042887,0.21636733085825482,0.5655044371788908,0.053269504024264246,0.34579373996602075,0.025199324650836994,0.42084065117869884,0.10863077097339395,0.5180573956646057,-0.30221572716540523,0.08107837999042887,0.21636733085825482,-0.3655974840969154
3,193
Scf skp2 mediated degradation of p27 p21
12
41
2.385858
0.017039
P51665,P49721,P28074,P61289,P24941,O43242,P28072,P25787,P28070,P11802,P60900,P20618
Processes and pathways
Reactome Pathways
msigdb_reactome
352,8,105,478,422,417,20,119,55,215,30,95
525,2356,1907,2050,1993,417,913,215,1916,95,422,2467,119,2162,2468,2400,55,20,105,2996,2998,1261,1446,8,352,3068,30,478,1631,2434,2802,1266,729,1545,1639,1584,929,795,2143,1523,1295
0.7258739119100094,-0.49595119132772597,-0.1790423277350827,-0.2709736160130218,-0.24003068040751657,0.856796727704752,0.42084065117869884,1.1993188415722877,-0.1790423277350827,1.8775608468012885,0.856796727704752,-0.5968579512594566,1.6409002994968682,-0.3337570158659335,-0.5968579512594566,-0.5292875863064875,2.301101464563815,3.308198222205599,1.7694486191853893,-1.3786049993712943,-1.3786049993712943,0.21636733085825482,0.10863077097339395,4.132037847844936,0.9409952878769652,-1.6685111568748416,3.0017959971834336,0.7920526088666452,-0.0031371136066703498,-0.5629231723307153,-0.9898877670258749,0.21636733085825482,0.5655044371788908,0.053269504024264246,-0.0031371136066703498,0.025199324650836994,0.42084065117869884,0.5180573956646057,-0.30221572716540523,0.08107837999042887,0.21636733085825482
3,193
Protein targeting to mitochondrion
11
48
2.383356
0.017156
Q99595,P30536,P55786,O14925,Q15388,Q8N4H5,O60830,Q9P0J0,Q5JRX3,Q9GZY8,Q9NS69
Processes and pathways
GO Biological process
msigdb_gobp
32,100,101,169,205,142,17,249,84,247,24
1619,1430,252,169,1909,711,17,3084,2728,2730,2642,395,1346,713,1388,915,3041,1165,100,2618,961,1129,1781,101,1213,855,205,1788,2560,2628,84,1460,142,2811,738,32,831,247,2668,24,249,1521,2743,984,2820,1476,2393,802
-0.0031371136066703498,0.10863077097339395,1.102589523776575,1.383857498630824,-0.1790423277350827,0.5655044371788908,3.6453743945093926,-1.7540346313524435,-0.8791073450641793,-0.8791073450641793,-0.7710198034073763,0.8780699365084367,0.16298471623624555,0.5655044371788908,0.13593136335059053,0.42084065117869884,-1.5424702465695177,0.26881271098746073,1.8007392900685555,-0.7355890326334656,0.39603391908014063,0.29469410743066005,-0.08979570423491805,1.8007392900685555,0.2427051145911597,0.4698445071041799,1.2371500809699392,-0.08979570423491805,-0.6656250951850902,-0.7355890326334656,2.0110474795908226,0.10863077097339395,1.5407221737348815,-0.9898877670258749,0.5655044371788908,2.9598669449402526,0.4940482237889104,1.1221876398575348,-0.7710198034073763,3.193291468873368,1.1221876398575348,0.08107837999042887,-0.8791073450641793,0.39603391908014063,-0.9898877670258749,0.10863077097339395,-0.49595119132772597,0.5180573956646057
3,193
Cholesterol binding
6
13
2.377441
0.017433
Q14849,P30536,P45880,Q14108,O15118,P21796
Functions
GO Molecular function
msigdb_gomf
294,100,38,51,208,26
208,2729,2969,26,2065,100,324,38,1131,51,294,1232,2767
1.2182943630695027,-0.8791073450641793,-1.2984677625692256,3.0940370861233606,-0.2709736160130218,1.8007392900685555,0.9822208710006587,2.7295242300793277,0.29469410743066005,2.391845426042903,1.0430115443451933,0.2427051145911597,-0.9157349411807121
3,193
Stabilization of p53
7
40
2.371486
0.017717
P49721,P28074,P28072,P25787,P28070,P60900,P20618
Processes and pathways
Reactome Pathways
msigdb_reactome
8,105,20,119,55,30,95
525,2356,1907,2050,1993,417,913,1533,2773,1916,95,2467,119,2162,2468,2400,55,20,105,2996,1209,2998,1261,1446,8,352,3068,30,478,1631,2434,2802,729,1545,167,929,795,2143,1523,1295
0.7258739119100094,-0.49595119132772597,-0.1790423277350827,-0.2709736160130218,-0.24003068040751657,0.856796727704752,0.42084065117869884,0.053269504024264246,-0.9526617479367557,-0.1790423277350827,1.8775608468012885,-0.5968579512594566,1.6409002994968682,-0.3337570158659335,-0.5968579512594566,-0.5292875863064875,2.301101464563815,3.308198222205599,1.7694486191853893,-1.3786049993712943,0.2427051145911597,-1.3786049993712943,0.21636733085825482,0.10863077097339395,4.132037847844936,0.9409952878769652,-1.6685111568748416,3.0017959971834336,0.7920526088666452,-0.0031371136066703498,-0.5629231723307153,-0.9898877670258749,0.5655044371788908,0.053269504024264246,1.41943529737493,0.42084065117869884,0.5180573956646057,-0.30221572716540523,0.08107837999042887,0.21636733085825482
3,193
membrane traffic protein
22
63
2.364927
0.018034
O95782,O00429,Q12907,A6NIH7,Q9H4M9,Q9HD42,Q13432,P43307,Q9H223,Q96FZ7,P50570,P78537,Q00765,Q8IUD2,Q9Y296,O00203,Q9Y2T2,Q9NX40,Q96RL7,Q8WUX9,Q9H269,Q96A65
Functions
Panther Protein class
panther_protein_class
627,505,631,15,546,283,31,36,567,566,559,680,682,357,485,472,503,373,497,639,642,388
15,472,505,1480,1958,748,1299,843,2059,627,1162,1773,2163,2069,1726,1170,36,2922,961,559,1781,2550,2859,2370,680,682,1875,2405,631,31,2288,357,1136,1227,1983,639,735,388,1846,980,566,2348,1185,497,3079,1144,567,642,1145,546,1192,2106,283,2491,373,1556,1151,1292,1152,1856,838,485,503
3.752502074253957,0.7920526088666452,0.7480967979523666,0.08107837999042887,-0.20938691832830006,0.5418751241716249,0.18979526604543842,0.4698445071041799,-0.2709736160130218,0.6352911062035237,0.26881271098746073,-0.08979570423491805,-0.3337570158659335,-0.2709736160130218,-0.0606293056858646,0.26881271098746073,2.8523931916992176,-1.1805061058028332,0.39603391908014063,0.7034844439548688,-0.08979570423491805,-0.6656250951850902,-1.065237448909853,-0.49595119132772597,0.5889482912953588,0.5889482912953588,-0.14899690656748693,-0.5292875863064875,0.6352911062035237,2.9809050828258044,-0.4301759669868179,0.9409952878769652,0.29469410743066005,0.2427051145911597,-0.20938691832830006,0.6352911062035237,0.5655044371788908,0.8991926986389834,-0.11924966294507812,0.39603391908014063,0.7034844439548688,-0.462913985518726,0.26881271098746073,0.7701555617414707,-1.7111232730375066,0.29469410743066005,0.7034844439548688,0.6352911062035237,0.29469410743066005,0.7258739119100094,0.26881271098746073,-0.2709736160130218,1.063003214209736,-0.5968579512594566,0.9201671263885668,0.053269504024264246,0.29469410743066005,0.21636733085825482,0.29469410743066005,-0.11924966294507812,0.4940482237889104,0.7920526088666452,0.7701555617414707
3,193
Lysosomal transport
17
39
2.360874
0.018232
P07602,O95295,O00203,Q9Y2T2,Q96FZ7,Q8IWJ2,O14964,Q99816,Q9UID3,O14617,Q8WUX9,Q14108,Q9HD42,O15118,Q9H269,Q9NZJ7,Q9UNK0
Processes and pathways
GO Biological process
msigdb_gobp
67,347,472,503,566,462,322,739,801,415,639,51,283,208,642,321,124
472,415,322,1480,208,1958,347,67,1255,1915,1162,1303,1773,1394,1629,1497,2982,51,2786,2809,462,639,1371,566,1185,739,1652,642,283,2458,321,1556,837,1151,801,1856,1294,124,503
0.7920526088666452,0.856796727704752,0.9822208710006587,0.08107837999042887,1.2182943630695027,-0.20938691832830006,0.9409952878769652,2.1802255667070183,0.21636733085825482,-0.1790423277350827,0.26881271098746073,0.18979526604543842,-0.08979570423491805,0.13593136335059053,-0.0031371136066703498,0.08107837999042887,-1.3383867666926692,2.391845426042903,-0.9526617479367557,-0.9898877670258749,0.813790292416791,0.6352911062035237,0.16298471623624555,0.7034844439548688,0.26881271098746073,0.5655044371788908,-0.0031371136066703498,0.6352911062035237,1.063003214209736,-0.5629231723307153,1.0026222188239642,0.053269504024264246,0.4940482237889104,0.29469410743066005,0.5180573956646057,-0.11924966294507812,0.21636733085825482,1.6409002994968682,0.7701555617414707
3,193
Asymmetric localization of pcp proteins
7
38
2.344268
0.019064
P49721,P28074,P28072,P25787,P28070,P60900,P20618
Processes and pathways
Reactome Pathways
msigdb_reactome
8,105,20,119,55,30,95
525,2356,1907,2050,1993,417,913,1916,95,2467,119,2162,2468,2400,55,20,105,2996,2998,1261,1446,8,352,3068,30,478,1631,2434,2802,729,1545,2942,167,929,795,2143,1523,1295
0.7258739119100094,-0.49595119132772597,-0.1790423277350827,-0.2709736160130218,-0.24003068040751657,0.856796727704752,0.42084065117869884,-0.1790423277350827,1.8775608468012885,-0.5968579512594566,1.6409002994968682,-0.3337570158659335,-0.5968579512594566,-0.5292875863064875,2.301101464563815,3.308198222205599,1.7694486191853893,-1.3786049993712943,-1.3786049993712943,0.21636733085825482,0.10863077097339395,4.132037847844936,0.9409952878769652,-1.6685111568748416,3.0017959971834336,0.7920526088666452,-0.0031371136066703498,-0.5629231723307153,-0.9898877670258749,0.5655044371788908,0.053269504024264246,-1.2195274337089115,1.41943529737493,0.42084065117869884,0.5180573956646057,-0.30221572716540523,0.08107837999042887,0.21636733085825482
3,193
Sterol binding
6
14
2.337625
0.019407
Q14849,P30536,P45880,Q14108,O15118,P21796
Functions
GO Molecular function
msigdb_gomf
294,100,38,51,208,26
208,2729,2969,26,2318,2065,100,324,38,1131,51,294,1232,2767
1.2182943630695027,-0.8791073450641793,-1.2984677625692256,3.0940370861233606,-0.462913985518726,-0.2709736160130218,1.8007392900685555,0.9822208710006587,2.7295242300793277,0.29469410743066005,2.391845426042903,1.0430115443451933,0.2427051145911597,-0.9157349411807121
3,193
Cellular transition metal ion homeostasis
12
21
2.330384
0.019786
O00203,P09601,Q8N511,Q9H3K6,P21399,Q15904,O14617,Q9Y487,O60826,O75027,Q8TAD4,O76003
Processes and pathways
GO Biological process
msigdb_gobp
472,7,139,700,576,460,415,153,672,673,280,187
472,415,1766,672,673,2360,187,749,1720,7,576,2508,2959,2554,1504,460,139,280,1190,700,153
0.7920526088666452,0.856796727704752,-0.08979570423491805,0.5889482912953588,0.5889482912953588,-0.49595119132772597,1.3114045548408733,0.5418751241716249,-0.0606293056858646,4.132037847844936,0.680925878721421,-0.631091924935383,-1.258847985434175,-0.6656250951850902,0.08107837999042887,0.813790292416791,1.5576536448951719,1.063003214209736,0.26881271098746073,0.5889482912953588,1.5065684931882488
3,193
E2f mediated regulation of dna replication
8
12
2.329274
0.019845
P49642,Q13416,Q9Y619,P06493,Q9UBD5,P14635,P09884,P06400
Processes and pathways
Reactome Pathways
msigdb_reactome
598,632,72,236,800,209,777,277
906,277,236,777,209,1536,1537,598,1311,632,800,72
0.42084065117869884,1.063003214209736,1.1416579910536835,0.5180573956646057,1.2182943630695027,0.053269504024264246,0.053269504024264246,0.6581956434453833,0.18979526604543842,0.6352911062035237,0.5180573956646057,2.166487793701175
3,193
Antigen processing cross presentation
15
52
2.323443
0.020155
P09429,P04439,P51665,P10321,Q14997,P49721,P28074,Q9UIQ6,O43242,P28072,P25787,Q03518,P28070,P60900,P20618
Processes and pathways
Reactome Pathways
msigdb_reactome
312,311,352,377,167,8,105,47,417,20,119,87,55,30,95
2463,525,2356,1907,2050,1993,989,417,2823,913,3020,311,312,377,1916,95,2467,119,2162,2468,2547,2400,55,20,105,2697,2996,2998,1261,1446,8,352,3068,2859,30,478,2074,1631,2434,2802,87,729,2707,1545,167,929,795,2143,47,1523,1295,1760
-0.5968579512594566,0.7258739119100094,-0.49595119132772597,-0.1790423277350827,-0.2709736160130218,-0.24003068040751657,0.3710194511388473,0.856796727704752,-1.0274130001280428,0.42084065117869884,-1.459939156603208,1.0026222188239642,1.0026222188239642,0.8991926986389834,-0.1790423277350827,1.8775608468012885,-0.5968579512594566,1.6409002994968682,-0.3337570158659335,-0.5968579512594566,-0.6656250951850902,-0.5292875863064875,2.301101464563815,3.308198222205599,1.7694486191853893,-0.8427789578797747,-1.3786049993712943,-1.3786049993712943,0.21636733085825482,0.10863077097339395,4.132037847844936,0.9409952878769652,-1.6685111568748416,-1.065237448909853,3.0017959971834336,0.7920526088666452,-0.2709736160130218,-0.0031371136066703498,-0.5629231723307153,-0.9898877670258749,1.9818952092384208,0.5655044371788908,-0.8427789578797747,0.053269504024264246,1.41943529737493,0.42084065117869884,0.5180573956646057,-0.30221572716540523,2.5046047789471104,0.08107837999042887,0.21636733085825482,-0.0606293056858646
3,193
Steroid metabolic process
18
67
2.322489
0.020207
O14734,P48449,Q14849,P30536,Q15392,Q15036,Q9UBM7,P35610,Q9UKR5,Q14739,Q8WTV0,Q13510,O15118,Q16850,Q9BQE5,P34913,P42765,P04062
Processes and pathways
GO Biological process
msigdb_gobp
251,99,294,100,70,367,141,324,143,175,18,50,208,93,27,190,61,158
251,208,1564,2729,574,3092,507,158,2991,1720,3166,1087,2397,2116,2507,2318,2065,3102,3164,752,100,190,324,1573,1091,3113,61,99,2165,2780,2167,1782,2511,1131,1686,2516,1874,50,1641,1320,175,294,367,1879,1834,70,1408,1739,1880,381,93,732,1740,1365,1329,18,3132,942,2764,27,2767,2350,141,1120,1425,143,3089
1.102589523776575,1.2182943630695027,0.025199324650836994,-0.8791073450641793,0.680925878721421,-1.7972452332773272,0.7480967979523666,1.4545942332074184,-1.3786049993712943,-0.0606293056858646,-2.823589938644955,0.3203531886001632,-0.5292875863064875,-0.30221572716540523,-0.631091924935383,-0.462913985518726,-0.2709736160130218,-1.8407550802597537,-2.7243005898102766,0.5418751241716249,1.8007392900685555,1.2930133010682965,0.9822208710006587,0.025199324650836994,0.3203531886001632,-1.928672515138034,2.2345531829313767,1.8317054739763257,-0.3337570158659335,-0.9526617479367557,-0.3337570158659335,-0.08979570423491805,-0.631091924935383,0.29469410743066005,-0.031744908526115174,-0.631091924935383,-0.14899690656748693,2.4045866103244666,-0.0031371136066703498,0.18979526604543842,1.3659083845750073,1.0430115443451933,0.9201671263885668,-0.14899690656748693,-0.11924966294507812,2.1802255667070183,0.13593136335059053,-0.0606293056858646,-0.14899690656748693,0.8991926986389834,1.9077445032407137,0.5655044371788908,-0.0606293056858646,0.16298471623624555,0.18979526604543842,3.4188452578218076,-2.1080983881921154,0.42084065117869884,-0.9157349411807121,3.0940370861233606,-0.9157349411807121,-0.462913985518726,1.5576536448951719,0.3203531886001632,0.13593136335059053,1.5407221737348815,-1.7540346313524435
3,193
Signaling by the b cell receptor bcr
8
49
2.318436
0.020426
P49721,P28074,P28072,P25787,P28070,P62942,P60900,P20618
Processes and pathways
Reactome Pathways
msigdb_reactome
8,105,20,119,55,148,30,95
525,2356,1907,2050,1993,989,417,1159,913,1387,2114,2063,1916,95,2467,119,2162,2468,2400,55,20,105,2996,2998,1261,1446,8,352,3068,30,478,1631,2434,2802,148,440,1266,756,729,3105,1545,1584,167,929,795,2143,1523,1295,1760
0.7258739119100094,-0.49595119132772597,-0.1790423277350827,-0.2709736160130218,-0.24003068040751657,0.3710194511388473,0.856796727704752,0.26881271098746073,0.42084065117869884,0.13593136335059053,-0.30221572716540523,-0.2709736160130218,-0.1790423277350827,1.8775608468012885,-0.5968579512594566,1.6409002994968682,-0.3337570158659335,-0.5968579512594566,-0.5292875863064875,2.301101464563815,3.308198222205599,1.7694486191853893,-1.3786049993712943,-1.3786049993712943,0.21636733085825482,0.10863077097339395,4.132037847844936,0.9409952878769652,-1.6685111568748416,3.0017959971834336,0.7920526088666452,-0.0031371136066703498,-0.5629231723307153,-0.9898877670258749,1.5065684931882488,0.8353709145003145,0.21636733085825482,0.5418751241716249,0.5655044371788908,-1.8407550802597537,0.053269504024264246,0.025199324650836994,1.41943529737493,0.42084065117869884,0.5180573956646057,-0.30221572716540523,0.08107837999042887,0.21636733085825482,-0.0606293056858646
3,193
Thin eyebrow
7
14
2.311092
0.020828
P48449,P14923,P41227,Q9UM00,O75419,P15924,Q96EK5
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
99,290,223,310,301,86,186
1157,301,3091,290,86,223,628,99,353,1828,1879,186,2305,310
0.26881271098746073,1.0228851550061475,-1.7972452332773272,1.0430115443451933,1.9818952092384208,1.1802219848882647,0.6352911062035237,1.8317054739763257,0.9409952878769652,-0.11924966294507812,-0.14899690656748693,1.3296832447901088,-0.4301759669868179,1.0228851550061475
3,193
Abc transporter disorders
8
41
2.30552
0.021137
P49721,P28074,Q9UBV2,P28072,P25787,P28070,P60900,P20618
Processes and pathways
Reactome Pathways
msigdb_reactome
8,105,152,20,119,55,30,95
525,2356,1907,2050,1993,417,913,2729,1916,95,2467,119,2162,2468,2400,55,20,105,2996,2998,1261,1446,8,352,3068,2982,30,478,1631,2434,2802,729,1545,167,929,795,2143,297,152,1523,1295
0.7258739119100094,-0.49595119132772597,-0.1790423277350827,-0.2709736160130218,-0.24003068040751657,0.856796727704752,0.42084065117869884,-0.8791073450641793,-0.1790423277350827,1.8775608468012885,-0.5968579512594566,1.6409002994968682,-0.3337570158659335,-0.5968579512594566,-0.5292875863064875,2.301101464563815,3.308198222205599,1.7694486191853893,-1.3786049993712943,-1.3786049993712943,0.21636733085825482,0.10863077097339395,4.132037847844936,0.9409952878769652,-1.6685111568748416,-1.3383867666926692,3.0017959971834336,0.7920526088666452,-0.0031371136066703498,-0.5629231723307153,-0.9898877670258749,0.5655044371788908,0.053269504024264246,1.41943529737493,0.42084065117869884,0.5180573956646057,-0.30221572716540523,1.0430115443451933,1.5065684931882488,0.08107837999042887,0.21636733085825482
3,193
Defective cftr causes cystic fibrosis
8
41
2.30552
0.021137
P49721,P28074,Q9UBV2,P28072,P25787,P28070,P60900,P20618
Processes and pathways
Reactome Pathways
msigdb_reactome
8,105,152,20,119,55,30,95
525,2356,1907,2050,1993,417,913,2729,1916,95,2467,119,2162,2468,2400,55,20,105,2996,2998,1261,1446,8,352,3068,2982,30,478,1631,2434,2802,729,1545,167,929,795,2143,297,152,1523,1295
0.7258739119100094,-0.49595119132772597,-0.1790423277350827,-0.2709736160130218,-0.24003068040751657,0.856796727704752,0.42084065117869884,-0.8791073450641793,-0.1790423277350827,1.8775608468012885,-0.5968579512594566,1.6409002994968682,-0.3337570158659335,-0.5968579512594566,-0.5292875863064875,2.301101464563815,3.308198222205599,1.7694486191853893,-1.3786049993712943,-1.3786049993712943,0.21636733085825482,0.10863077097339395,4.132037847844936,0.9409952878769652,-1.6685111568748416,-1.3383867666926692,3.0017959971834336,0.7920526088666452,-0.0031371136066703498,-0.5629231723307153,-0.9898877670258749,0.5655044371788908,0.053269504024264246,1.41943529737493,0.42084065117869884,0.5180573956646057,-0.30221572716540523,1.0430115443451933,1.5065684931882488,0.08107837999042887,0.21636733085825482
3,193
Protein insertion into membrane
11
26
2.300413
0.021425
Q15629,O14737,Q15070,P46379,Q7L5D6,Q9P0J0,P30419,Q9NPA0,Q9P0I2,Q9NS69,Q8WWC4
Processes and pathways
GO Biological process
msigdb_gobp
130,252,326,75,343,249,361,644,646,24,587
252,624,1482,2728,915,361,2618,75,2074,2202,326,130,2628,1883,343,1696,587,826,644,24,646,249,1198,1476,2393,802
1.102589523776575,0.6352911062035237,0.08107837999042887,-0.8791073450641793,0.42084065117869884,0.9201671263885668,-0.7355890326334656,2.0968345345583104,-0.2709736160130218,-0.3655974840969154,0.9822208710006587,1.5912312904288737,-0.7355890326334656,-0.14899690656748693,0.9616792082789943,-0.031744908526115174,0.680925878721421,0.4940482237889104,0.6352911062035237,3.193291468873368,0.6352911062035237,1.1221876398575348,0.26881271098746073,0.10863077097339395,-0.49595119132772597,0.5180573956646057
3,193
Vacuole organization
22
54
2.300055
0.021445
Q16706,Q8N511,Q7Z3C6,P04062,P42345,P62820,P53365,P50897,Q9UHD9,Q9P253,P10253,Q14108,O75503,Q9HC07,P54802,O95295,O00203,P50851,Q9H2M9,Q14457,Q9H269,P11117
Processes and pathways
GO Biological process
msigdb_gobp
789,139,278,158,530,532,164,37,704,837,303,51,184,469,339,347,472,721,768,493,642,125
472,1666,2823,184,2730,347,1346,158,1864,2645,303,125,1821,998,530,721,37,1629,164,339,1397,965,532,2405,51,493,818,1179,789,1365,278,935,139,1698,1935,1371,2411,2741,1185,1802,642,768,469,945,2458,837,704,1856,2391,1294,1808,1238,2820,1663
0.7920526088666452,-0.031744908526115174,-1.0274130001280428,1.3296832447901088,-0.8791073450641793,0.9409952878769652,0.16298471623624555,1.4545942332074184,-0.14899690656748693,-0.7710198034073763,1.0228851550061475,1.6244355839494933,-0.11924966294507812,0.3710194511388473,0.7258739119100094,0.5655044371788908,2.8414299150165303,-0.0031371136066703498,1.41943529737493,0.9616792082789943,0.13593136335059053,0.39603391908014063,0.7258739119100094,-0.5292875863064875,2.391845426042903,0.7701555617414707,0.4940482237889104,0.26881271098746073,0.5180573956646057,0.16298471623624555,1.063003214209736,0.42084065117869884,1.5576536448951719,-0.031744908526115174,-0.1790423277350827,0.16298471623624555,-0.5292875863064875,-0.8791073450641793,0.26881271098746073,-0.08979570423491805,0.6352911062035237,0.5418751241716249,0.813790292416791,0.42084065117869884,-0.5629231723307153,0.4940482237889104,0.5889482912953588,-0.11924966294507812,-0.49595119132772597,0.21636733085825482,-0.08979570423491805,0.2427051145911597,-0.9898877670258749,-0.0031371136066703498
3,193
Regulation of runx2 expression and activity
7
42
2.298398
0.021539
P49721,P28074,P28072,P25787,P28070,P60900,P20618
Processes and pathways
Reactome Pathways
msigdb_reactome
8,105,20,119,55,30,95
525,2356,1907,2050,1993,417,913,1916,95,2467,119,2162,2468,2400,55,20,105,2996,1493,2998,1261,1446,8,352,3068,30,478,1631,2434,2802,1266,729,1545,1639,1584,167,929,795,2143,1523,3089,1295
0.7258739119100094,-0.49595119132772597,-0.1790423277350827,-0.2709736160130218,-0.24003068040751657,0.856796727704752,0.42084065117869884,-0.1790423277350827,1.8775608468012885,-0.5968579512594566,1.6409002994968682,-0.3337570158659335,-0.5968579512594566,-0.5292875863064875,2.301101464563815,3.308198222205599,1.7694486191853893,-1.3786049993712943,0.08107837999042887,-1.3786049993712943,0.21636733085825482,0.10863077097339395,4.132037847844936,0.9409952878769652,-1.6685111568748416,3.0017959971834336,0.7920526088666452,-0.0031371136066703498,-0.5629231723307153,-0.9898877670258749,0.21636733085825482,0.5655044371788908,0.053269504024264246,-0.0031371136066703498,0.025199324650836994,1.41943529737493,0.42084065117869884,0.5180573956646057,-0.30221572716540523,0.08107837999042887,-1.7540346313524435,0.21636733085825482
3,193
Retinoblastoma gene in cancer
22
48
2.296836
0.021628
P09455,P00374,P35244,P33981,P09884,P06400,Q14566,P24941,O75419,P09429,Q9Y619,O14757,P14635,Q15054,P11802,P49642,Q14527,P33991,Q07864,P31350,P26583,P06493
Processes and pathways
WikiPathways
msigdb_wp
128,14,397,654,777,277,293,422,301,312,72,571,209,459,215,598,605,719,225,718,107,236
571,301,1252,877,14,2773,277,236,312,128,777,2733,215,2828,209,1163,1490,2005,422,781,847,107,1676,718,654,719,1038,397,2958,1678,2236,598,1130,1006,1634,225,1639,3120,605,293,2129,459,1588,2215,2456,1859,1903,72
0.680925878721421,1.0228851550061475,0.21636733085825482,0.44544306819693447,3.902465612713916,-0.9526617479367557,1.063003214209736,1.1416579910536835,1.0026222188239642,1.6078795867372875,0.5180573956646057,-0.8791073450641793,1.1993188415722877,-1.0274130001280428,1.2182943630695027,0.26881271098746073,0.08107837999042887,-0.24003068040751657,0.856796727704752,0.5180573956646057,0.4698445071041799,1.7536794627358119,-0.031744908526115174,0.5655044371788908,0.612209574085093,0.5655044371788908,0.34579373996602075,0.8780699365084367,-1.258847985434175,-0.031744908526115174,-0.3977371338220593,0.6581956434453833,0.29469410743066005,0.3710194511388473,-0.0031371136066703498,1.1802219848882647,-0.0031371136066703498,-1.9730801058799055,0.6581956434453833,1.0430115443451933,-0.30221572716540523,0.813790292416791,0.025199324650836994,-0.3655974840969154,-0.5629231723307153,-0.11924966294507812,-0.14899690656748693,2.166487793701175
3,193
Hedgehog on state
13
43
2.296521
0.021646
P51665,Q14997,P49721,Q9Y496,P61289,P28074,O43242,P28072,P48729,P25787,P28070,P60900,P20618
Processes and pathways
Reactome Pathways
msigdb_reactome
352,167,8,504,478,105,417,20,338,119,55,30,95
525,2356,1907,2050,1993,417,913,1916,95,2467,119,2162,2468,2400,55,20,105,2996,2998,1261,338,2431,1446,8,352,3068,30,478,1631,2434,2802,729,1545,1048,167,929,2177,2298,795,2143,1523,1295,504
0.7258739119100094,-0.49595119132772597,-0.1790423277350827,-0.2709736160130218,-0.24003068040751657,0.856796727704752,0.42084065117869884,-0.1790423277350827,1.8775608468012885,-0.5968579512594566,1.6409002994968682,-0.3337570158659335,-0.5968579512594566,-0.5292875863064875,2.301101464563815,3.308198222205599,1.7694486191853893,-1.3786049993712943,-1.3786049993712943,0.21636733085825482,0.9616792082789943,-0.5629231723307153,0.10863077097339395,4.132037847844936,0.9409952878769652,-1.6685111568748416,3.0017959971834336,0.7920526088666452,-0.0031371136066703498,-0.5629231723307153,-0.9898877670258749,0.5655044371788908,0.053269504024264246,0.34579373996602075,1.41943529737493,0.42084065117869884,-0.3337570158659335,-0.4301759669868179,0.5180573956646057,-0.30221572716540523,0.08107837999042887,0.21636733085825482,0.7701555617414707
3,193
Carboxylic acid binding
9
30
2.295243
0.021719
P09455,P07602,Q32P28,O15460,P13674,P00374,P34896,Q9NZJ7,P41440
Functions
GO Molecular function
msigdb_gomf
128,67,132,375,199,14,337,321,243
2421,2051,375,2113,451,14,1033,1085,67,128,960,1162,2777,199,2065,2319,1491,337,2938,243,578,629,2475,2242,1581,972,132,1284,2492,321
-0.5629231723307153,-0.2709736160130218,0.8991926986389834,-0.30221572716540523,0.813790292416791,3.902465612713916,0.34579373996602075,0.3203531886001632,2.1802255667070183,1.6078795867372875,0.39603391908014063,0.26881271098746073,-0.9526617479367557,1.2558874980500507,-0.2709736160130218,-0.462913985518726,0.08107837999042887,0.9616792082789943,-1.2195274337089115,1.1221876398575348,0.680925878721421,0.6352911062035237,-0.5968579512594566,-0.3977371338220593,0.025199324650836994,0.39603391908014063,1.574489660490009,0.21636733085825482,-0.5968579512594566,1.0026222188239642
3,193
Metabolism of vitamins and cofactors
12
44
2.293697
0.021808
P09455,P78417,P43490,P35270,Q9H2D1,O75874,P00374,Q99707,Q9NRN7,Q9HC21,P41440,Q13057
Processes and pathways
Reactome Pathways
msigdb_reactome
128,1,96,131,35,136,14,308,239,112,243,156
2051,549,136,2967,14,3092,1033,1671,915,128,2695,960,2734,2364,1967,1259,337,2938,131,243,96,1577,629,1,156,2862,1327,611,2913,1647,3124,1226,1933,1282,1284,308,35,112,2105,2872,239,568,2921,2580
-0.2709736160130218,0.7034844439548688,1.5576536448951719,-1.2984677625692256,3.902465612713916,-1.7972452332773272,0.34579373996602075,-0.031744908526115174,0.42084065117869884,1.6078795867372875,-0.8427789578797747,0.39603391908014063,-0.8791073450641793,-0.49595119132772597,-0.20938691832830006,0.21636733085825482,0.9616792082789943,-1.2195274337089115,1.574489660490009,1.1221876398575348,1.8775608468012885,0.025199324650836994,0.6352911062035237,5.401623940688195,1.4720196860623391,-1.065237448909853,0.18979526604543842,0.6581956434453833,-1.1417840001131578,-0.0031371136066703498,-2.0177869473716163,0.2427051145911597,-0.1790423277350827,0.21636733085825482,0.21636733085825482,1.0228851550061475,2.863316355216428,1.7058661157411827,-0.2709736160130218,-1.065237448909853,1.1416579910536835,0.7034844439548688,-1.1417840001131578,-0.6656250951850902
3,193
Rhizomelia
7
14
2.284665
0.022333
Q03164,Q15392,Q9UBM7,Q14739,Q9BV10,Q8WTW3,O75718
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
68,70,141,175,115,245,394
1156,1031,2822,394,530,1094,68,175,1879,70,245,2528,115,141
0.26881271098746073,0.34579373996602075,-1.0274130001280428,0.8780699365084367,0.7258739119100094,0.3203531886001632,2.1802255667070183,1.3659083845750073,-0.14899690656748693,2.1802255667070183,1.1221876398575348,-0.631091924935383,1.6735598720423626,1.5576536448951719
3,193
Water soluble vitamin metabolic process
7
21
2.264734
0.023529
P78417,Q9H2D1,Q9NRN7,P00374,Q99707,Q9HC21,P41440
Processes and pathways
GO Biological process
msigdb_gobp
1,35,239,14,308,112,243
14,2695,2364,2003,1259,337,2938,243,578,629,1,2340,1226,1282,2976,1284,308,35,112,239,3143
3.902465612713916,-0.8427789578797747,-0.49595119132772597,-0.24003068040751657,0.21636733085825482,0.9616792082789943,-1.2195274337089115,1.1221876398575348,0.680925878721421,0.6352911062035237,5.401623940688195,-0.462913985518726,0.2427051145911597,0.21636733085825482,-1.2984677625692256,0.21636733085825482,1.0228851550061475,2.863316355216428,1.7058661157411827,1.1416579910536835,-2.2458099647275738
3,193
Heterogeneous
16
40
2.26468
0.023532
O75844,Q16836,P35222,Q14126,P51798,Q9Y619,P53634,P00367,P50570,P07196,Q9NR77,P54098,P15924,P04792,Q9BQE5,P12235
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
129,295,720,427,291,72,724,575,559,551,52,85,86,185,27,527
991,129,1533,575,3020,914,2773,185,1720,2230,551,1162,527,86,1774,1675,848,720,2426,1574,2855,559,2780,291,724,85,1173,1131,427,758,1011,1880,295,1284,27,2105,52,1947,1811,72
0.3710194511388473,1.5912312904288737,0.053269504024264246,0.680925878721421,-1.459939156603208,0.42084065117869884,-0.9526617479367557,1.3296832447901088,-0.0606293056858646,-0.3977371338220593,0.7034844439548688,0.26881271098746073,0.7258739119100094,1.9818952092384208,-0.08979570423491805,-0.031744908526115174,0.4698445071041799,0.5655044371788908,-0.5629231723307153,0.025199324650836994,-1.065237448909853,0.7034844439548688,-0.9526617479367557,1.0430115443451933,0.5655044371788908,1.9965069209559112,0.26881271098746073,0.29469410743066005,0.856796727704752,0.5418751241716249,0.3710194511388473,-0.14899690656748693,1.0430115443451933,0.21636733085825482,3.0940370861233606,-0.2709736160130218,2.391845426042903,-0.1790423277350827,-0.08979570423491805,2.166487793701175
3,193
Abc family proteins mediated transport
9
51
2.240104
0.025084
P49721,P28074,Q9UBV2,P28072,P28070,P25787,P08183,P60900,P20618
Processes and pathways
Reactome Pathways
msigdb_reactome
8,105,152,20,55,119,147,30,95
525,2356,1907,2050,1993,417,673,913,2729,2000,147,1916,1089,95,2467,119,2162,2468,2400,55,20,105,752,1259,2996,1726,2998,1261,1446,8,352,3068,2982,2624,30,478,1631,2434,2802,729,1545,167,929,613,795,2143,297,2873,152,1523,1295
0.7258739119100094,-0.49595119132772597,-0.1790423277350827,-0.2709736160130218,-0.24003068040751657,0.856796727704752,0.5889482912953588,0.42084065117869884,-0.8791073450641793,-0.24003068040751657,1.5065684931882488,-0.1790423277350827,0.3203531886001632,1.8775608468012885,-0.5968579512594566,1.6409002994968682,-0.3337570158659335,-0.5968579512594566,-0.5292875863064875,2.301101464563815,3.308198222205599,1.7694486191853893,0.5418751241716249,0.21636733085825482,-1.3786049993712943,-0.0606293056858646,-1.3786049993712943,0.21636733085825482,0.10863077097339395,4.132037847844936,0.9409952878769652,-1.6685111568748416,-1.3383867666926692,-0.7355890326334656,3.0017959971834336,0.7920526088666452,-0.0031371136066703498,-0.5629231723307153,-0.9898877670258749,0.5655044371788908,0.053269504024264246,1.41943529737493,0.42084065117869884,0.6581956434453833,0.5180573956646057,-0.30221572716540523,1.0430115443451933,-1.065237448909853,1.5065684931882488,0.08107837999042887,0.21636733085825482
3,193
Necrotic cell death
8
17
2.238933
0.02516
O00429,P30536,Q13546,Q13510,O15294,O60443,Q7Z3C6,P16989
Processes and pathways
GO Biological process
msigdb_gobp
505,100,265,50,174,54,278,313
505,174,54,959,2773,1085,527,313,2957,100,1577,50,265,278,1112,2253,1805
0.7480967979523666,1.3659083845750073,2.3403299146257823,0.39603391908014063,-0.9526617479367557,0.3203531886001632,0.7258739119100094,1.0026222188239642,-1.258847985434175,1.8007392900685555,0.025199324650836994,2.4045866103244666,1.0828619555333547,1.063003214209736,0.3203531886001632,-0.3977371338220593,-0.08979570423491805
3,193
Pcp ce pathway
7
47
2.236856
0.025296
P49721,P28074,P28072,P25787,P28070,P60900,P20618
Processes and pathways
Reactome Pathways
msigdb_reactome
8,105,20,119,55,30,95
525,2356,1907,2050,1993,417,913,2059,627,2114,1086,1769,1916,95,2467,119,2162,2468,2400,55,20,105,2996,2998,1261,1446,8,352,1731,3068,30,478,1631,2434,2802,2370,1635,729,1545,2942,167,929,1846,795,2143,1523,1295
0.7258739119100094,-0.49595119132772597,-0.1790423277350827,-0.2709736160130218,-0.24003068040751657,0.856796727704752,0.42084065117869884,-0.2709736160130218,0.6352911062035237,-0.30221572716540523,0.3203531886001632,-0.08979570423491805,-0.1790423277350827,1.8775608468012885,-0.5968579512594566,1.6409002994968682,-0.3337570158659335,-0.5968579512594566,-0.5292875863064875,2.301101464563815,3.308198222205599,1.7694486191853893,-1.3786049993712943,-1.3786049993712943,0.21636733085825482,0.10863077097339395,4.132037847844936,0.9409952878769652,-0.0606293056858646,-1.6685111568748416,3.0017959971834336,0.7920526088666452,-0.0031371136066703498,-0.5629231723307153,-0.9898877670258749,-0.49595119132772597,-0.0031371136066703498,0.5655044371788908,0.053269504024264246,-1.2195274337089115,1.41943529737493,0.42084065117869884,-0.11924966294507812,0.5180573956646057,-0.30221572716540523,0.08107837999042887,0.21636733085825482
3,193
Steroid binding
8
19
2.229432
0.025785
Q14849,P30536,P45880,P35610,Q14108,O15118,P21796,P04062
Functions
GO Molecular function
msigdb_gomf
294,100,38,324,51,208,26,158
1526,208,435,2729,158,2991,2969,26,2318,2065,100,324,1091,38,1131,51,294,1232,2767
0.053269504024264246,1.2182943630695027,0.8353709145003145,-0.8791073450641793,1.4545942332074184,-1.3786049993712943,-1.2984677625692256,3.0940370861233606,-0.462913985518726,-0.2709736160130218,1.8007392900685555,0.9822208710006587,0.3203531886001632,2.7295242300793277,0.29469410743066005,2.391845426042903,1.0430115443451933,0.2427051145911597,-0.9157349411807121
3,193
Hypomimic face
7
13
2.224161
0.026138
P35270,Q6P1N0,Q04637,P54098,Q96RR1,P12235,P04062
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
131,543,492,85,445,527,158
650,2540,158,527,131,85,492,1504,543,1794,1185,445,2306
0.612209574085093,-0.6656250951850902,1.4545942332074184,0.7258739119100094,1.574489660490009,1.9965069209559112,0.7701555617414707,0.08107837999042887,0.7258739119100094,-0.08979570423491805,0.26881271098746073,0.8353709145003145,-0.4301759669868179
3,193
Alcohol metabolic process
20
86
2.223768
0.026164
P35270,Q9UBM7,O75874,P00374,Q8WTV0,Q9BQE5,P04062,Q14849,Q14739,Q13510,P42765,P34913,Q15392,P35610,Q9BY49,O15118,P48735,Q16850,P48449,Q15036
Processes and pathways
GO Biological process
msigdb_gobp
131,141,136,14,18,27,158,294,175,50,61,190,70,324,345,208,90,93,99,367
2612,208,1668,1381,650,3008,2054,2056,1564,136,1670,2729,3117,14,3092,507,158,1720,3040,2543,1087,2777,2397,2003,2116,2507,2063,997,3102,2119,1823,190,131,324,1573,61,1727,99,90,2165,3025,2621,3086,2780,599,1782,2511,3147,655,1131,1686,1923,2516,2126,855,50,1641,1320,175,294,367,1879,1834,70,1880,381,3131,93,1836,1740,611,2249,2762,1933,18,2946,2985,27,1599,345,2188,1606,141,1120,2392,1990
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3,193
Corneal opacity
11
52
2.222992
0.026216
O75844,O43505,Q9UBM7,P34913,P16278,O95202,Q06136,Q13510,P53701,P10619,P04062
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
129,39,141,190,263,262,16,50,363,60,158
1243,1157,989,39,473,2933,1669,2822,1083,129,1564,1251,262,1818,914,158,2501,996,777,60,263,2677,360,1772,190,2698,1726,2473,599,962,363,1682,2624,2330,2126,16,1132,2478,50,1052,2021,1505,759,2290,3006,1338,1900,141,2459,2391,2048,1760
0.21636733085825482,0.26881271098746073,0.3710194511388473,2.7180994529009332,0.7920526088666452,-1.2195274337089115,-0.031744908526115174,-1.0274130001280428,0.3203531886001632,1.5912312904288737,0.025199324650836994,0.21636733085825482,1.0828619555333547,-0.11924966294507812,0.42084065117869884,1.4545942332074184,-0.631091924935383,0.3710194511388473,0.5180573956646057,2.261350745716217,1.0828619555333547,-0.8067497779060742,0.9201671263885668,-0.08979570423491805,1.2930133010682965,-0.8427789578797747,-0.0606293056858646,-0.5968579512594566,0.6581956434453833,0.39603391908014063,0.9201671263885668,-0.031744908526115174,-0.7355890326334656,-0.462913985518726,-0.30221572716540523,3.703535835976282,0.29469410743066005,-0.5968579512594566,2.4045866103244666,0.34579373996602075,-0.24003068040751657,0.08107837999042887,0.5418751241716249,-0.4301759669868179,-1.3786049993712943,0.18979526604543842,-0.14899690656748693,1.5576536448951719,-0.5629231723307153,-0.49595119132772597,-0.24003068040751657,-0.0606293056858646
3,193
Endoplasmic reticulum
137
464
2.221964
0.026286
Q9NR31,O00429,Q15437,P07099,P30519,P09601,O00767,P04035,P24390,Q9NX74,Q06136,Q9BQE5,Q9UMX5,P42345,Q9UQB8,P62820,P83881,P43307,Q9Y282,Q9H223,Q96G23,P80303,O43731,Q13510,Q14108,O95674,Q7L0J3,Q99720,P10619,Q02818,Q86UE4,Q15392,O95197,O95470,P00367,P21399,P27105,Q9H6V9,Q6NUM9,Q9BU23,Q03518,Q9BT22,Q16850,O60506,P48449,P30536,O00213,P51648,Q2TAA5,Q8TB61,Q96HY6,Q9BV10,Q9P0I2,Q5BJF2,Q9NPA0,Q12959,Q9UNK0,P46778,O43681,O75844,Q15629,Q32P28,Q02878,Q8N511,Q9UBM7,Q9BRR6,Q9UKR5,Q9Y680,Q9UBV2,Q9BRK5,P62942,P42858,O60725,P04062,Q16611,Q14739,O75503,Q16880,Q9NQC3,Q5VUD6,Q6NUQ1,P13674,Q9H3N1,O15118,O95487,Q9H488,Q13190,P06493,Q9H2J4,Q8IV08,Q9NZ08,Q96AY3,Q7Z3C6,Q9UL25,Q9BUN8,Q14849,P67812,O43852,O15498,Q9UM00,Q86YV9,P62847,P55327,Q9BTY2,Q96A57,P04439,Q8WVQ1,Q13641,P35610,P11047,P46776,Q15800,P10321,O15460,Q5VYK3,Q9P2W9,O75718,Q07065,Q14257,Q01105,Q9UBF8,O60476,P62266,O15173,Q9UBR2,Q15904,P48723,Q9HD20,Q9Y296,Q9Y244,Q96RL7,Q86XL3,Q14457,P50402,P48651,Q8TCT9,Q99735
Localization
GO Cellular component
msigdb_gocc
523,505,514,5,6,7,506,507,13,548,16,27,29,530,33,532,533,36,570,567,41,46,49,50,51,550,53,57,60,63,585,70,71,574,575,576,577,80,611,619,87,91,93,596,99,100,591,599,108,638,640,115,646,117,644,121,124,628,624,129,130,132,630,139,141,140,143,144,152,151,148,155,157,158,171,175,184,188,195,201,202,199,212,208,213,230,226,236,248,267,272,269,278,299,297,294,292,288,286,310,307,305,316,320,319,311,332,325,324,349,362,381,377,375,382,414,394,399,400,425,432,419,439,435,470,460,454,483,485,502,497,494,493,490,489,520,521
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3,193
Negative regulation of autophagy
9
21
2.220536
0.026382
P42345,P30536,P09601,Q9NNW5,Q9NQ88,Q14457,Q04637,O15118,P10619
Processes and pathways
GO Biological process
msigdb_gobp
530,100,7,547,178,493,492,208,60
208,1382,2823,2773,2002,7,60,100,1040,530,786,1314,492,493,1935,2741,547,178,1947,1521,648
1.2182943630695027,0.13593136335059053,-1.0274130001280428,-0.9526617479367557,-0.24003068040751657,4.132037847844936,2.261350745716217,1.8007392900685555,0.34579373996602075,0.7258739119100094,0.5180573956646057,0.18979526604543842,0.7701555617414707,0.7701555617414707,-0.1790423277350827,-0.8791073450641793,0.7258739119100094,1.3659083845750073,-0.1790423277350827,0.08107837999042887,0.6352911062035237
3,193
Positive regulation of epithelial cell proliferation
6
20
2.219287
0.026467
P09429,Q86VI3,Q9NQC3,P09601,P26583,Q9H2J4
Processes and pathways
GO Biological process
msigdb_gobp
312,296,195,7,107,248
1030,1563,1817,2853,312,7,349,2830,1771,107,720,1040,1356,2709,1739,2630,296,1649,248,195
0.34579373996602075,0.025199324650836994,-0.11924966294507812,-1.065237448909853,1.0026222188239642,4.132037847844936,0.9409952878769652,-1.0274130001280428,-0.08979570423491805,1.7536794627358119,0.5655044371788908,0.34579373996602075,0.16298471623624555,-0.8427789578797747,-0.0606293056858646,-0.7355890326334656,1.0430115443451933,-0.0031371136066703498,1.1221876398575348,1.2930133010682965
3,193
Cellular monovalent inorganic cation homeostasis
8
26
2.218823
0.026499
Q9Y6M7,P50897,O95295,Q8N511,Q9HC07,Q92544,Q9Y487,O75503
Processes and pathways
GO Biological process
msigdb_gobp
102,37,347,139,469,407,153,184
184,347,2991,2644,1962,2396,2234,1168,37,1629,1869,2369,1211,2554,1785,460,139,407,793,1371,469,1340,1710,153,987,102
1.3296832447901088,0.9409952878769652,-1.3786049993712943,-0.7710198034073763,-0.20938691832830006,-0.5292875863064875,-0.3977371338220593,0.26881271098746073,2.8414299150165303,-0.0031371136066703498,-0.14899690656748693,-0.49595119132772597,0.2427051145911597,-0.6656250951850902,-0.08979570423491805,0.813790292416791,1.5576536448951719,0.8780699365084367,0.5180573956646057,0.16298471623624555,0.813790292416791,0.18979526604543842,-0.031744908526115174,1.5065684931882488,0.39603391908014063,1.8007392900685555
3,193
Vacuolar transport
20
46
2.214578
0.026789
Q9UID3,Q9HD42,Q96FZ7,O14617,Q9P253,Q14108,Q9NZJ7,P07602,Q8IWJ2,O14964,Q99816,O15118,O95295,O00203,Q9Y2T2,Q96RL7,Q8WUX9,Q14457,Q9H269,Q9UNK0
Processes and pathways
GO Biological process
msigdb_gobp
801,283,566,415,837,51,321,67,462,322,739,208,347,472,503,497,639,493,642,124
472,415,322,1480,208,1958,347,67,1255,1915,1162,1303,1773,1394,1629,1497,2982,2554,51,493,2786,2809,462,639,2345,1371,566,1185,497,1230,739,1652,642,1145,864,283,2458,321,1556,837,1151,801,1856,1294,124,503
0.7920526088666452,0.856796727704752,0.9822208710006587,0.08107837999042887,1.2182943630695027,-0.20938691832830006,0.9409952878769652,2.1802255667070183,0.21636733085825482,-0.1790423277350827,0.26881271098746073,0.18979526604543842,-0.08979570423491805,0.13593136335059053,-0.0031371136066703498,0.08107837999042887,-1.3383867666926692,-0.6656250951850902,2.391845426042903,0.7701555617414707,-0.9526617479367557,-0.9898877670258749,0.813790292416791,0.6352911062035237,-0.462913985518726,0.16298471623624555,0.7034844439548688,0.26881271098746073,0.7701555617414707,0.2427051145911597,0.5655044371788908,-0.0031371136066703498,0.6352911062035237,0.29469410743066005,0.4698445071041799,1.063003214209736,-0.5629231723307153,1.0026222188239642,0.053269504024264246,0.4940482237889104,0.29469410743066005,0.5180573956646057,-0.11924966294507812,0.21636733085825482,1.6409002994968682,0.7701555617414707
3,193
Reticulocytopenia
12
21
2.213322
0.026875
P62273,P61254,P08708,Q07020,P18077,P62081,Q9BXW9,P61313,P62847,P62899,P42766,P62244
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
1004,755,916,813,1035,601,412,364,305,785,557,438
1435,916,1035,1539,557,2071,1353,1312,755,364,1044,601,438,1004,305,1828,785,1543,813,412,1617
0.10863077097339395,0.42084065117869884,0.34579373996602075,0.053269504024264246,0.7034844439548688,-0.2709736160130218,0.16298471623624555,0.18979526604543842,0.5418751241716249,0.9201671263885668,0.34579373996602075,0.6581956434453833,0.8353709145003145,0.3710194511388473,1.0228851550061475,-0.11924966294507812,0.5180573956646057,0.053269504024264246,0.4940482237889104,0.8780699365084367,0.025199324650836994
3,193
Dna replication
17
32
2.212811
0.026911
P49642,P33991,Q07864,Q13416,Q9Y619,P24941,Q9UBD5,Q99741,O75419,P35244,Q15054,P35251,P41440,P09884,Q9Y2S7,Q7L590,Q14566
Processes and pathways
WikiPathways
msigdb_wp
598,719,225,632,72,422,800,697,301,397,459,555,243,777,648,216,293
906,301,777,2828,1163,422,781,1676,1258,719,1627,1038,397,2958,2698,555,1678,2236,243,2702,598,1311,1494,225,632,293,459,216,697,800,648,72
0.42084065117869884,1.0228851550061475,0.5180573956646057,-1.0274130001280428,0.26881271098746073,0.856796727704752,0.5180573956646057,-0.031744908526115174,0.21636733085825482,0.5655044371788908,-0.0031371136066703498,0.34579373996602075,0.8780699365084367,-1.258847985434175,-0.8427789578797747,0.7034844439548688,-0.031744908526115174,-0.3977371338220593,1.1221876398575348,-0.8427789578797747,0.6581956434453833,0.18979526604543842,0.08107837999042887,1.1802219848882647,0.6352911062035237,1.0430115443451933,0.813790292416791,1.1993188415722877,0.5889482912953588,0.5180573956646057,0.6352911062035237,2.166487793701175
3,193
G1 s dna damage checkpoints
7
42
2.207257
0.027296
P49721,P28074,P28072,P25787,P28070,P60900,P20618
Processes and pathways
Reactome Pathways
msigdb_reactome
8,105,20,119,55,30,95
525,2356,1907,2050,571,1993,417,913,1533,2773,1916,95,422,2467,119,2162,2468,2400,55,20,105,2996,1209,2998,1261,1446,8,352,3068,30,478,1631,2434,2802,729,1545,167,929,795,2143,1523,1295
0.7258739119100094,-0.49595119132772597,-0.1790423277350827,-0.2709736160130218,0.680925878721421,-0.24003068040751657,0.856796727704752,0.42084065117869884,0.053269504024264246,-0.9526617479367557,-0.1790423277350827,1.8775608468012885,0.856796727704752,-0.5968579512594566,1.6409002994968682,-0.3337570158659335,-0.5968579512594566,-0.5292875863064875,2.301101464563815,3.308198222205599,1.7694486191853893,-1.3786049993712943,0.2427051145911597,-1.3786049993712943,0.21636733085825482,0.10863077097339395,4.132037847844936,0.9409952878769652,-1.6685111568748416,3.0017959971834336,0.7920526088666452,-0.0031371136066703498,-0.5629231723307153,-0.9898877670258749,0.5655044371788908,0.053269504024264246,1.41943529737493,0.42084065117869884,0.5180573956646057,-0.30221572716540523,0.08107837999042887,0.21636733085825482
3,193
Transition metal ion homeostasis
12
25
2.204234
0.027508
O00203,P30519,P09601,Q8N511,Q9H3K6,P21399,Q15904,O14617,Q9Y487,O60826,Q8TAD4,O76003
Processes and pathways
GO Biological process
msigdb_gobp
472,6,7,139,700,576,460,415,153,672,280,187
472,415,1766,672,673,2360,187,749,2825,1720,7,576,6,2508,2959,2554,2128,1504,460,139,2961,280,1190,700,153
0.7920526088666452,0.856796727704752,-0.08979570423491805,0.5889482912953588,0.5889482912953588,-0.49595119132772597,1.3114045548408733,0.5418751241716249,-1.0274130001280428,-0.0606293056858646,4.132037847844936,0.680925878721421,4.195509236421808,-0.631091924935383,-1.258847985434175,-0.6656250951850902,-0.30221572716540523,0.08107837999042887,0.813790292416791,1.5576536448951719,-1.258847985434175,1.063003214209736,0.26881271098746073,0.5889482912953588,1.5065684931882488
3,193
Slc mediated transmembrane transport
9
21
2.201028
0.027734
Q9Y6M7,Q9H936,Q8TB61,Q99808,P53985,Q8TAD4,Q70HW3,Q9UBX3,P12235
Processes and pathways
Reactome Pathways
msigdb_reactome
102,78,638,664,82,280,88,259,527
1161,2061,2695,527,751,2508,1000,1039,82,1211,1504,1835,1643,88,280,638,664,1852,78,259,102
0.26881271098746073,-0.2709736160130218,-0.8427789578797747,0.7258739119100094,0.5418751241716249,-0.631091924935383,0.3710194511388473,0.34579373996602075,2.025517574520846,0.2427051145911597,0.08107837999042887,-0.11924966294507812,-0.0031371136066703498,1.9524555180193348,1.063003214209736,0.6352911062035237,0.612209574085093,-0.11924966294507812,2.068511822464931,1.102589523776575,1.8007392900685555
3,193
Sparse and thin eyebrow
6
12
2.199185
0.027865
P48449,P14923,P41227,Q9UM00,P15924,Q96EK5
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
99,290,223,310,86,186
1157,3091,290,86,223,628,99,353,1828,1879,186,310
0.26881271098746073,-1.7972452332773272,1.0430115443451933,1.9818952092384208,1.1802219848882647,0.6352911062035237,1.8317054739763257,0.9409952878769652,-0.11924966294507812,-0.14899690656748693,1.3296832447901088,1.0228851550061475
3,193
Proteasome complex
15
49
2.198002
0.027949
P51665,O43396,Q14997,P49721,Q5VYK3,P61289,P28074,Q8IWV7,O43242,P28072,P25787,P28070,P04792,P60900,P20618
Localization
GO Cellular component
msigdb_gocc
352,196,167,8,382,478,105,495,417,20,119,55,185,30,95
525,2356,1907,2050,1993,417,196,913,185,1916,95,2467,119,2162,2468,2400,55,20,105,2996,2998,1261,1446,8,352,2653,1042,3068,2982,30,478,1631,2434,2802,1785,729,1545,167,929,1407,2082,382,495,795,2143,2900,1523,1295,2821
0.7258739119100094,-0.49595119132772597,-0.1790423277350827,-0.2709736160130218,-0.24003068040751657,0.856796727704752,1.2745080889897082,0.42084065117869884,1.3296832447901088,-0.1790423277350827,1.8775608468012885,-0.5968579512594566,1.6409002994968682,-0.3337570158659335,-0.5968579512594566,-0.5292875863064875,2.301101464563815,3.308198222205599,1.7694486191853893,-1.3786049993712943,-1.3786049993712943,0.21636733085825482,0.10863077097339395,4.132037847844936,0.9409952878769652,-0.7710198034073763,0.34579373996602075,-1.6685111568748416,-1.3383867666926692,3.0017959971834336,0.7920526088666452,-0.0031371136066703498,-0.5629231723307153,-0.9898877670258749,-0.08979570423491805,0.5655044371788908,0.053269504024264246,1.41943529737493,0.42084065117869884,0.13593136335059053,-0.2709736160130218,0.8991926986389834,0.7701555617414707,0.5180573956646057,-0.30221572716540523,-1.103361115024735,0.08107837999042887,0.21636733085825482,-0.9898877670258749
3,193
Regulation of autophagy
24
89
2.196632
0.028047
O75844,O00429,P09601,Q13137,Q9NNW5,Q9Y487,P42858,P21796,P12235,P04062,P19474,Q9NQ88,Q9NZJ7,P04792,P10619,P09429,P07602,Q9NZ45,Q96DM3,O15118,P30536,Q14457,Q04637,Q96A65
Processes and pathways
GO Biological process
msigdb_gobp
129,505,7,512,547,153,155,26,527,158,43,178,321,185,60,312,67,333,211,208,100,493,492,388
1619,1432,505,1122,2904,208,1668,1381,1382,1909,2823,843,129,1532,1346,158,1768,2773,185,1161,2231,67,2002,3033,312,7,60,527,43,1165,3009,2649,26,2234,100,1208,2959,1040,530,2012,155,1394,1129,2625,2554,3077,786,1314,1687,492,2783,512,687,1833,493,2806,818,1053,1222,585,2208,2719,2484,1698,1935,793,388,211,2741,1185,2946,1230,768,2187,547,178,1947,333,321,1521,1660,704,1710,1237,648,2820,153,872,1760
-0.0031371136066703498,0.10863077097339395,0.7480967979523666,0.29469410743066005,-1.1417840001131578,1.2182943630695027,-0.031744908526115174,0.13593136335059053,0.13593136335059053,-0.1790423277350827,-1.0274130001280428,0.4698445071041799,1.5912312904288737,0.053269504024264246,0.16298471623624555,1.4545942332074184,-0.08979570423491805,-0.9526617479367557,1.3296832447901088,0.26881271098746073,-0.3977371338220593,2.1802255667070183,-0.24003068040751657,-1.5010550842325505,1.0026222188239642,4.132037847844936,2.261350745716217,0.7258739119100094,2.6013806888194835,0.26881271098746073,-1.419122462160247,-0.7710198034073763,3.0940370861233606,-0.3977371338220593,1.8007392900685555,0.2427051145911597,-1.258847985434175,0.34579373996602075,0.7258739119100094,-0.24003068040751657,1.4720196860623391,0.13593136335059053,0.29469410743066005,-0.7355890326334656,-0.6656250951850902,-1.7111232730375066,0.5180573956646057,0.18979526604543842,-0.031744908526115174,0.7701555617414707,-0.9526617479367557,0.7480967979523666,0.5889482912953588,-0.11924966294507812,0.7701555617414707,-0.9898877670258749,0.4940482237889104,0.34579373996602075,0.2427051145911597,0.680925878721421,-0.3655974840969154,-0.8427789578797747,-0.5968579512594566,-0.031744908526115174,-0.1790423277350827,0.5180573956646057,0.8991926986389834,1.2182943630695027,-0.8791073450641793,0.26881271098746073,-1.2195274337089115,0.2427051145911597,0.5418751241716249,-0.3337570158659335,0.7258739119100094,1.3659083845750073,-0.1790423277350827,0.9822208710006587,1.0026222188239642,0.08107837999042887,-0.0031371136066703498,0.5889482912953588,-0.031744908526115174,0.2427051145911597,0.6352911062035237,-0.9898877670258749,1.5065684931882488,0.4698445071041799,-0.0606293056858646
3,193
Abnormality of the shoulder girdle musculature
12
32
2.19559
0.028121
O00429,P46976,P07602,P11047,Q14331,Q9Y487,P54098,Q96RR1,Q9Y5L0,Q9NZJ7,P50402,P12235
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
505,254,67,349,306,153,85,445,222,321,490,527
1992,505,1481,748,1563,2822,914,2230,551,67,349,527,2545,2237,254,490,85,2982,2739,1971,1268,306,1059,2295,445,1514,321,1424,153,222,1759,871
-0.24003068040751657,0.7480967979523666,0.08107837999042887,0.5418751241716249,0.025199324650836994,-1.0274130001280428,0.42084065117869884,-0.3977371338220593,0.7034844439548688,2.1802255667070183,0.9409952878769652,0.7258739119100094,-0.6656250951850902,-0.3977371338220593,1.102589523776575,0.7701555617414707,1.9965069209559112,-1.3383867666926692,-0.8791073450641793,-0.20938691832830006,0.21636733085825482,1.0228851550061475,0.34579373996602075,-0.4301759669868179,0.8353709145003145,0.08107837999042887,1.0026222188239642,0.13593136335059053,1.5065684931882488,1.1993188415722877,-0.0606293056858646,0.4698445071041799
3,193
Regulation of mrna stability by proteins that bind au rich elements
15
63
2.195176
0.028151
P51665,Q14997,P49721,P28074,P61289,Q92973,O43242,Q04637,P28072,P20618,P25787,P28070,P04792,P60900,Q01105
Processes and pathways
Reactome Pathways
msigdb_reactome
352,167,8,105,478,370,417,492,20,95,119,55,185,30,425
525,2356,1907,2050,1993,1624,417,913,2312,185,1255,918,1916,95,2467,119,2162,2468,2400,55,20,105,1492,2401,2996,1777,2998,1261,1446,8,352,3068,30,478,1631,2434,2802,1499,425,492,2655,729,1545,1217,2172,167,929,2518,2520,635,2289,691,2212,370,3052,795,2143,2262,1420,1523,1295,953,1080
0.7258739119100094,-0.49595119132772597,-0.1790423277350827,-0.2709736160130218,-0.24003068040751657,-0.0031371136066703498,0.856796727704752,0.42084065117869884,-0.462913985518726,1.3296832447901088,0.21636733085825482,0.42084065117869884,-0.1790423277350827,1.8775608468012885,-0.5968579512594566,1.6409002994968682,-0.3337570158659335,-0.5968579512594566,-0.5292875863064875,2.301101464563815,3.308198222205599,1.7694486191853893,0.08107837999042887,-0.5292875863064875,-1.3786049993712943,-0.08979570423491805,-1.3786049993712943,0.21636733085825482,0.10863077097339395,4.132037847844936,0.9409952878769652,-1.6685111568748416,3.0017959971834336,0.7920526088666452,-0.0031371136066703498,-0.5629231723307153,-0.9898877670258749,0.08107837999042887,0.856796727704752,0.7701555617414707,-0.7710198034073763,0.5655044371788908,0.053269504024264246,0.2427051145911597,-0.3337570158659335,1.41943529737493,0.42084065117869884,-0.631091924935383,-0.631091924935383,0.6352911062035237,-0.4301759669868179,0.5889482912953588,-0.3655974840969154,0.9201671263885668,-1.5424702465695177,0.5180573956646057,-0.30221572716540523,-0.3977371338220593,0.13593136335059053,0.08107837999042887,0.21636733085825482,0.42084065117869884,0.34579373996602075
3,193
Golgi apparatus
63
166
2.193023
0.028306
Q16706,O60499,P09601,Q9H2V7,Q96K12,Q93050,P53367,P24390,P16278,Q9BV57,Q9UID3,Q14CX7,Q9BRK5,Q9HB40,Q8TAD4,O00231,Q8NC54,P53365,P50897,P67812,Q8TDW0,Q9UBF8,Q96MW5,P80303,O60476,P50570,Q8IXU6,Q9NWM8,Q9UQ16,P55327,O95456,O60637,Q12893,P40818,Q02818,Q8N3C0,Q8IYS2,Q5VW38,O15260,P04439,Q8WVQ1,Q99996,Q6NUQ1,Q9HC07,Q8IWJ2,Q9NRZ9,Q5KU26,Q96A49,P18858,O00461,P50851,Q13190,O95295,O00203,Q8NCH0,Q969E2,P40616,Q9NUJ3,Q08378,Q8NE00,O15258,Q9HD45,Q8IZA0
Localization
Protein Atlas Subcellular
protein_atlas_subcellular_location_all
789,376,7,271,270,793,137,13,263,411,801,788,151,22,280,525,692,164,37,292,824,432,828,46,419,559,48,836,838,316,805,58,581,314,63,586,193,65,804,311,332,465,202,469,462,743,342,616,716,98,721,226,347,472,234,110,488,645,757,387,746,258,385
1813,1906,1431,472,525,98,2747,2158,1480,1244,990,746,804,991,1957,3008,1765,1296,419,2727,376,58,1299,2879,2359,2822,1862,2309,347,805,1533,311,1720,2826,7,2193,1162,2365,263,716,2318,13,1675,1822,1205,2678,2698,920,1039,488,314,2922,1576,1094,1495,559,721,37,3086,1130,164,137,2368,1783,316,1043,292,46,1922,3026,1450,63,757,814,1875,581,226,2687,1833,3045,1405,788,1504,789,2629,342,2022,2337,65,2658,1365,202,1884,1366,1181,2983,1840,2338,974,935,462,1981,48,1593,2339,193,385,586,892,2091,692,234,387,280,1982,1059,2601,824,332,1699,1278,1113,793,110,616,270,828,895,1286,2573,465,3175,151,2790,411,1802,271,2350,2742,2301,1946,1020,2187,2104,2769,22,469,2106,258,2490,743,2219,645,2610,836,2149,432,2817,1855,801,1293,3060,838,2903,1618,904
-0.11924966294507812,-0.1790423277350827,0.10863077097339395,0.7920526088666452,0.7258739119100094,1.8623538295308035,-0.9157349411807121,-0.3337570158659335,0.08107837999042887,0.21636733085825482,0.3710194511388473,0.5418751241716249,0.4940482237889104,0.3710194511388473,-0.20938691832830006,-1.419122462160247,-0.08979570423491805,0.18979526604543842,0.856796727704752,-0.8791073450641793,0.8991926986389834,2.2746598733113577,0.18979526604543842,-1.103361115024735,-0.49595119132772597,-1.0274130001280428,-0.14899690656748693,-0.462913985518726,0.9409952878769652,0.4940482237889104,0.053269504024264246,1.0026222188239642,-0.0606293056858646,-1.0274130001280428,4.132037847844936,-0.3655974840969154,0.26881271098746073,-0.49595119132772597,1.0828619555333547,0.5655044371788908,-0.462913985518726,3.9784678086896657,-0.031744908526115174,-0.11924966294507812,0.2427051145911597,-0.8067497779060742,-0.8427789578797747,0.42084065117869884,0.34579373996602075,0.7701555617414707,1.0026222188239642,-1.1805061058028332,0.025199324650836994,0.3203531886001632,0.08107837999042887,0.7034844439548688,0.5655044371788908,2.8414299150165303,-1.7540346313524435,0.29469410743066005,1.41943529737493,1.5576536448951719,-0.49595119132772597,-0.08979570423491805,1.0026222188239642,0.34579373996602075,1.0430115443451933,2.516874712130047,-0.1790423277350827,-1.459939156603208,0.10863077097339395,2.22106366880997,0.5418751241716249,0.4940482237889104,-0.14899690656748693,0.680925878721421,1.1802219848882647,-0.8067497779060742,-0.11924966294507812,-1.5424702465695177,0.13593136335059053,0.5180573956646057,0.08107837999042887,0.5180573956646057,-0.7355890326334656,0.9616792082789943,-0.24003068040751657,-0.462913985518726,2.193900422541388,-0.7710198034073763,0.16298471623624555,1.2558874980500507,-0.14899690656748693,0.16298471623624555,0.26881271098746073,-1.3383867666926692,-0.11924966294507812,-0.462913985518726,0.39603391908014063,0.42084065117869884,0.813790292416791,-0.20938691832830006,2.492284212516803,0.025199324650836994,-0.462913985518726,1.2930133010682965,0.8991926986389834,0.680925878721421,0.44544306819693447,-0.2709736160130218,0.5889482912953588,1.1610022318711952,0.8991926986389834,1.063003214209736,-0.20938691832830006,0.34579373996602075,-0.7004574638193659,0.4940482237889104,0.9822208710006587,-0.031744908526115174,0.21636733085825482,0.3203531886001632,0.5180573956646057,1.7378265912614526,0.6581956434453833,1.0828619555333547,0.4940482237889104,0.44544306819693447,0.21636733085825482,-0.6656250951850902,0.813790292416791,-3.1286406154115016,1.5065684931882488,-0.9526617479367557,0.8780699365084367,-0.08979570423491805,1.0828619555333547,-0.462913985518726,-0.8791073450641793,-0.4301759669868179,-0.1790423277350827,0.3710194511388473,-0.3337570158659335,-0.2709736160130218,-0.9157349411807121,3.24170793389333,0.813790292416791,-0.2709736160130218,1.102589523776575,-0.5968579512594566,0.5655044371788908,-0.3655974840969154,0.6352911062035237,-0.7004574638193659,0.4940482237889104,-0.30221572716540523,0.856796727704752,-0.9898877670258749,-0.11924966294507812,0.5180573956646057,0.21636733085825482,-1.5841846451243686,0.4940482237889104,-1.103361115024735,0.025199324650836994,0.44544306819693447
3,193
Apoptosis
18
119
2.192657
0.028332
O14737,Q03164,O95197,P09601,Q9UHX1,P46379,P42858,Q16611,Q13546,P06493,Q9NQ88,O15294,Q9P0J0,Q96A26,Q9H2J4,P52756,Q9UDX5,P21796
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
252,68,71,7,135,75,155,171,265,236,178,174,249,181,248,304,89,26
591,3115,1241,2582,252,174,1909,473,2358,748,1669,1563,913,2394,2730,71,574,1346,713,1387,1533,1768,2773,1720,2114,236,7,751,1165,1352,26,1304,2234,1168,2957,879,529,2012,155,75,852,1041,2682,1781,304,478,1448,2513,2910,1687,561,68,1831,2127,2437,1502,2078,685,687,265,2479,2864,493,1321,1102,2081,1103,635,171,1456,1883,2087,1743,1884,1411,1981,2444,2294,1983,2094,2211,2603,1649,2032,181,1283,2604,2605,2298,2486,2034,2098,2144,1895,834,1801,1803,248,1114,1377,1602,178,2490,1117,1947,2043,321,249,89,2669,770,135,3054,2153,1859,985,2820,1475,2461
0.6581956434453833,-1.9730801058799055,0.21636733085825482,-0.7004574638193659,1.102589523776575,1.3659083845750073,-0.1790423277350827,0.7920526088666452,-0.49595119132772597,0.5418751241716249,-0.031744908526115174,0.025199324650836994,0.42084065117869884,-0.5292875863064875,-0.8791073450641793,2.166487793701175,0.680925878721421,0.16298471623624555,0.5655044371788908,0.13593136335059053,0.053269504024264246,-0.08979570423491805,-0.9526617479367557,-0.0606293056858646,-0.30221572716540523,1.1416579910536835,4.132037847844936,0.5418751241716249,0.26881271098746073,0.16298471623624555,3.0940370861233606,0.18979526604543842,-0.3977371338220593,0.26881271098746073,-1.258847985434175,0.44544306819693447,0.7258739119100094,-0.24003068040751657,1.4720196860623391,2.0968345345583104,0.4698445071041799,0.34579373996602075,-0.8067497779060742,-0.08979570423491805,1.0228851550061475,0.7920526088666452,0.10863077097339395,-0.631091924935383,-1.1417840001131578,-0.031744908526115174,0.7034844439548688,2.1802255667070183,-0.11924966294507812,-0.30221572716540523,-0.5629231723307153,0.08107837999042887,-0.2709736160130218,0.5889482912953588,0.5889482912953588,1.0828619555333547,-0.5968579512594566,-1.065237448909853,0.7701555617414707,0.18979526604543842,0.3203531886001632,-0.2709736160130218,0.3203531886001632,0.6352911062035237,1.383857498630824,0.10863077097339395,-0.14899690656748693,-0.2709736160130218,-0.0606293056858646,-0.14899690656748693,0.13593136335059053,-0.20938691832830006,-0.5629231723307153,-0.4301759669868179,-0.20938691832830006,-0.2709736160130218,-0.3655974840969154,-0.7004574638193659,-0.0031371136066703498,-0.24003068040751657,1.3478507399601813,0.21636733085825482,-0.7004574638193659,-0.7004574638193659,-0.4301759669868179,-0.5968579512594566,-0.24003068040751657,-0.2709736160130218,-0.30221572716540523,-0.14899690656748693,0.4940482237889104,-0.08979570423491805,-0.08979570423491805,1.1221876398575348,0.3203531886001632,0.16298471623624555,0.025199324650836994,1.3659083845750073,-0.5968579512594566,0.3203531886001632,-0.1790423277350827,-0.24003068040751657,1.0026222188239642,1.1221876398575348,1.9524555180193348,-0.7710198034073763,0.5418751241716249,1.574489660490009,-1.5424702465695177,-0.30221572716540523,-0.11924966294507812,0.39603391908014063,-0.9898877670258749,0.10863077097339395,-0.5629231723307153
3,193
Protein targeting
26
114
2.188565
0.028628
Q15629,O14737,Q16543,Q8N4H5,O60830,Q9NS69,O95429,O60725,Q99595,P43307,O14925,O14617,Q14108,P57105,P46379,Q8IWJ2,Q15388,O14964,Q7L5D6,Q5JRX3,P30536,P55786,O00203,Q9Y2T2,Q9P0J0,Q9GZY8
Processes and pathways
GO Biological process
msigdb_gobp
130,252,266,142,17,24,395,157,32,36,169,415,51,317,75,462,205,322,343,84,100,101,472,503,249,247
2581,1619,1430,472,415,252,572,169,322,1909,711,624,1482,157,17,1083,3084,1300,2728,2730,2642,395,1346,713,1388,915,2001,2675,3041,1255,1303,1165,1773,577,2321,3034,100,2880,529,1492,2618,2402,1726,36,75,1394,961,1210,1129,1629,1781,101,2624,317,2859,1097,2197,2074,2198,1045,1543,1499,1213,1687,855,2438,51,1738,205,130,1788,266,2560,2628,84,2630,343,2206,2809,1460,3049,462,142,2811,497,3106,1650,738,1230,32,831,247,864,2668,1608,24,945,249,1521,2743,867,1613,1340,984,3126,868,1294,503,2820,2355,1476,2393,802,1812
-0.7004574638193659,-0.0031371136066703498,0.10863077097339395,0.7920526088666452,0.856796727704752,1.102589523776575,0.680925878721421,1.383857498630824,0.9822208710006587,-0.1790423277350827,0.5655044371788908,0.6352911062035237,0.08107837999042887,1.4545942332074184,3.6453743945093926,0.3203531886001632,-1.7540346313524435,0.18979526604543842,-0.8791073450641793,-0.8791073450641793,-0.7710198034073763,0.8780699365084367,0.16298471623624555,0.5655044371788908,0.13593136335059053,0.42084065117869884,-0.24003068040751657,-0.8067497779060742,-1.5424702465695177,0.21636733085825482,0.18979526604543842,0.26881271098746073,-0.08979570423491805,0.680925878721421,-0.462913985518726,-1.5010550842325505,1.8007392900685555,-1.103361115024735,0.7258739119100094,0.08107837999042887,-0.7355890326334656,-0.5292875863064875,-0.0606293056858646,2.8523931916992176,2.0968345345583104,0.13593136335059053,0.39603391908014063,0.2427051145911597,0.29469410743066005,-0.0031371136066703498,-0.08979570423491805,1.8007392900685555,-0.7355890326334656,1.0026222188239642,-1.065237448909853,0.3203531886001632,-0.3655974840969154,-0.2709736160130218,-0.3655974840969154,0.34579373996602075,0.053269504024264246,0.08107837999042887,0.2427051145911597,-0.031744908526115174,0.4698445071041799,-0.5629231723307153,2.391845426042903,-0.0606293056858646,1.2371500809699392,1.5912312904288737,-0.08979570423491805,1.0828619555333547,-0.6656250951850902,-0.7355890326334656,2.0110474795908226,-0.7355890326334656,0.9616792082789943,-0.3655974840969154,-0.9898877670258749,0.10863077097339395,-1.5424702465695177,0.813790292416791,1.5407221737348815,-0.9898877670258749,0.7701555617414707,-1.8407550802597537,-0.0031371136066703498,0.5655044371788908,0.2427051145911597,2.9598669449402526,0.4940482237889104,1.1221876398575348,0.4698445071041799,-0.7710198034073763,0.025199324650836994,3.193291468873368,0.42084065117869884,1.1221876398575348,0.08107837999042887,-0.8791073450641793,0.4698445071041799,0.025199324650836994,0.18979526604543842,0.39603391908014063,-2.0177869473716163,0.4698445071041799,0.21636733085825482,0.7701555617414707,-0.9898877670258749,-0.462913985518726,0.10863077097339395,-0.49595119132772597,0.5180573956646057,-0.08979570423491805
3,193
Arthritis
12
40
2.186127
0.028806
O75844,Q9H488,P10321,Q8WVQ1,P51798,Q9NZ08,Q14739,Q13510,Q14108,P14174,P28070,P04062
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
129,230,377,332,291,272,175,50,51,242,55,158
1430,375,911,129,1534,3020,914,158,996,2315,377,2734,242,2677,1774,2735,55,1577,721,291,1783,1870,2801,2738,2074,2126,50,51,175,2376,820,332,2185,640,497,230,1751,272,2949,1525
0.10863077097339395,0.8991926986389834,0.42084065117869884,1.5912312904288737,0.053269504024264246,-1.459939156603208,0.42084065117869884,1.4545942332074184,0.3710194511388473,-0.462913985518726,0.8991926986389834,-0.8791073450641793,1.1221876398575348,-0.8067497779060742,-0.08979570423491805,-0.8791073450641793,2.301101464563815,0.025199324650836994,0.5655044371788908,1.0430115443451933,-0.08979570423491805,-0.14899690656748693,-0.9898877670258749,-0.8791073450641793,-0.2709736160130218,-0.30221572716540523,2.4045866103244666,2.391845426042903,1.3659083845750073,-0.49595119132772597,0.4940482237889104,0.9822208710006587,-0.3337570158659335,0.6352911062035237,0.7701555617414707,1.1802219848882647,-0.0606293056858646,1.0828619555333547,-1.2195274337089115,0.08107837999042887
3,193
Regulation of pten stability and activity
7
42
2.184564
0.028921
P49721,P28074,P28072,P25787,P28070,P60900,P20618
Processes and pathways
Reactome Pathways
msigdb_reactome
8,105,20,119,55,30,95
525,2356,1907,2050,1993,417,913,1916,1165,95,2467,119,2162,2468,2400,55,20,105,529,2996,2998,1394,1261,1446,8,352,3068,30,478,1631,2434,2802,1500,729,1545,167,929,795,2143,1523,3089,1295
0.7258739119100094,-0.49595119132772597,-0.1790423277350827,-0.2709736160130218,-0.24003068040751657,0.856796727704752,0.42084065117869884,-0.1790423277350827,0.26881271098746073,1.8775608468012885,-0.5968579512594566,1.6409002994968682,-0.3337570158659335,-0.5968579512594566,-0.5292875863064875,2.301101464563815,3.308198222205599,1.7694486191853893,0.7258739119100094,-1.3786049993712943,-1.3786049993712943,0.13593136335059053,0.21636733085825482,0.10863077097339395,4.132037847844936,0.9409952878769652,-1.6685111568748416,3.0017959971834336,0.7920526088666452,-0.0031371136066703498,-0.5629231723307153,-0.9898877670258749,0.08107837999042887,0.5655044371788908,0.053269504024264246,1.41943529737493,0.42084065117869884,0.5180573956646057,-0.30221572716540523,0.08107837999042887,-1.7540346313524435,0.21636733085825482
3,193
Secretory granule membrane
13
62
2.182655
0.029061
P07602,P10321,P30519,Q5T9A4,P42785,O60784,O95721,P10253,Q8TAD4,P15924,Q9NZJ7,Q07065,Q9NQX7
Localization
GO Cellular component
msigdb_gocc
67,377,6,354,9,420,302,303,280,86,321,399,220
2463,1526,594,804,1716,420,2308,2540,451,2059,302,3020,67,303,377,1915,1162,1303,86,1351,577,6,2508,1392,1000,2276,9,923,1495,1396,1629,1497,2368,1871,1784,965,2513,2626,399,2706,1360,1216,1318,2711,2019,932,354,1365,2524,2093,280,1461,793,1280,2919,1144,2768,1605,220,321,2691,839
-0.5968579512594566,0.053269504024264246,0.6581956434453833,0.4940482237889104,-0.0606293056858646,0.856796727704752,-0.462913985518726,-0.6656250951850902,0.813790292416791,-0.2709736160130218,1.0228851550061475,-1.459939156603208,2.1802255667070183,1.0228851550061475,0.8991926986389834,-0.1790423277350827,0.26881271098746073,0.18979526604543842,1.9818952092384208,0.16298471623624555,0.680925878721421,4.195509236421808,-0.631091924935383,0.13593136335059053,0.3710194511388473,-0.4301759669868179,4.117747886511145,0.42084065117869884,0.08107837999042887,0.13593136335059053,-0.0031371136066703498,0.08107837999042887,-0.49595119132772597,-0.14899690656748693,-0.08979570423491805,0.39603391908014063,-0.631091924935383,-0.7355890326334656,0.8780699365084367,-0.8427789578797747,0.16298471623624555,0.2427051145911597,0.18979526604543842,-0.8427789578797747,-0.24003068040751657,0.42084065117869884,0.9409952878769652,0.16298471623624555,-0.631091924935383,-0.2709736160130218,1.063003214209736,0.10863077097339395,0.5180573956646057,0.21636733085825482,-1.1417840001131578,0.29469410743066005,-0.9157349411807121,0.025199324650836994,1.1993188415722877,1.0026222188239642,-0.8067497779060742,0.4940482237889104
3,193
Endosomal transport
40
71
2.181183
0.02917
Q15057,O60499,P53367,Q9UID3,Q9C0C9,Q9H4M9,Q9HD42,Q4KMP7,O60493,O60749,Q4J6C6,O60271,Q9H223,Q96FZ7,O15498,O60784,O14617,P78537,O60826,O75503,Q96D71,O15260,Q4V328,Q8IWJ2,Q15904,O14964,P49257,Q9Y5X3,P61106,Q8IUD2,O75436,O00203,Q13190,Q15036,Q9Y5X1,P40616,Q8WUX9,Q9P2D3,Q9H269,Q14203
Processes and pathways
GO Biological process
msigdb_gobp
380,376,137,801,1067,546,283,541,774,274,1055,907,567,566,286,420,415,680,672,184,980,804,688,462,460,322,961,872,965,357,843,472,226,367,1029,488,639,250,642,758
472,415,322,804,286,907,774,376,274,420,672,843,184,1386,488,1170,961,1629,2737,137,2982,2625,1784,965,1398,680,1635,226,2128,2374,2942,758,367,380,1322,1179,460,1054,1055,541,688,1365,2809,357,462,639,1699,2345,1892,980,566,1185,2349,1067,567,642,1145,546,283,2458,1556,250,1151,1292,1660,801,3074,1294,1237,1029,872
0.7920526088666452,0.856796727704752,0.9822208710006587,0.4940482237889104,1.0430115443451933,0.42084065117869884,0.5180573956646057,0.8991926986389834,1.063003214209736,0.856796727704752,0.5889482912953588,0.4698445071041799,1.3296832447901088,0.13593136335059053,0.7701555617414707,0.26881271098746073,0.39603391908014063,-0.0031371136066703498,-0.8791073450641793,1.5576536448951719,-1.3383867666926692,-0.7355890326334656,-0.08979570423491805,0.39603391908014063,0.13593136335059053,0.5889482912953588,-0.0031371136066703498,1.1802219848882647,-0.30221572716540523,-0.49595119132772597,-1.2195274337089115,0.5418751241716249,0.9201671263885668,0.8991926986389834,0.18979526604543842,0.26881271098746073,0.813790292416791,0.34579373996602075,0.34579373996602075,0.7258739119100094,0.5889482912953588,0.16298471623624555,-0.9898877670258749,0.9409952878769652,0.813790292416791,0.6352911062035237,-0.031744908526115174,-0.462913985518726,-0.14899690656748693,0.39603391908014063,0.7034844439548688,0.26881271098746073,-0.462913985518726,0.34579373996602075,0.7034844439548688,0.6352911062035237,0.29469410743066005,0.7258739119100094,1.063003214209736,-0.5629231723307153,0.053269504024264246,1.1221876398575348,0.29469410743066005,0.21636733085825482,-0.0031371136066703498,0.5180573956646057,-1.6685111568748416,0.21636733085825482,0.2427051145911597,0.3710194511388473,0.4698445071041799
3,193
Interleukin 1 signaling
13
47
2.181049
0.02918
P09429,P51665,Q14997,P49721,P28074,P61289,O43242,P61088,P28072,P25787,P28070,P60900,P20618
Processes and pathways
Reactome Pathways
msigdb_reactome
312,352,167,8,105,478,417,455,20,119,55,30,95
525,2356,1907,2050,1993,989,417,913,1720,312,1916,95,2467,119,2162,2468,2400,55,20,105,2996,2998,1261,1446,8,352,3068,30,455,478,1631,2434,2802,1266,2200,756,729,1545,1584,167,929,3037,795,2143,1523,1295,1760
0.7258739119100094,-0.49595119132772597,-0.1790423277350827,-0.2709736160130218,-0.24003068040751657,0.3710194511388473,0.856796727704752,0.42084065117869884,-0.0606293056858646,1.0026222188239642,-0.1790423277350827,1.8775608468012885,-0.5968579512594566,1.6409002994968682,-0.3337570158659335,-0.5968579512594566,-0.5292875863064875,2.301101464563815,3.308198222205599,1.7694486191853893,-1.3786049993712943,-1.3786049993712943,0.21636733085825482,0.10863077097339395,4.132037847844936,0.9409952878769652,-1.6685111568748416,3.0017959971834336,0.813790292416791,0.7920526088666452,-0.0031371136066703498,-0.5629231723307153,-0.9898877670258749,0.21636733085825482,-0.3655974840969154,0.5418751241716249,0.5655044371788908,0.053269504024264246,0.025199324650836994,1.41943529737493,0.42084065117869884,-1.5010550842325505,0.5180573956646057,-0.30221572716540523,0.08107837999042887,0.21636733085825482,-0.0606293056858646
3,193
Peptidase activity
44
115
4.155568
0.000032
P42785,Q9H3G5,Q969V3,Q5JRX3,Q14694,Q01804,P55210,P17655,Q96FW1,P28070,P55786,Q9BYT8,P07858,Q9HBH5,O43847,Q9Y4P1,P13798,Q9HB40,P54578,P22695,Q9NZ08,Q6GQQ9,Q4J6C6,P49720,P60900,P49721,Q5TDH0,P28072,Q7L266,P55212,Q96RU2,Q9Y5K5,O15484,Q9NUQ7,P42575,Q9NY33,O75844,Q9BT78,Q86UV5,P48147,P10619,P09960,P25789,O14773
Functions
GO Molecular function
msigdb_gomf
4,5,6,131,613,372,604,258,441,136,26,570,154,450,152,310,530,47,174,533,51,199,61,414,539,64,429,193,621,82,218,359,329,513,96,644,101,638,384,475,592,591,595,117
1044,2479,117,1354,329,152,1255,101,1609,1847,1364,1366,1741,1742,1492,154,591,592,3049,530,1375,258,1496,533,595,136,193,898,2410,1069,2311,1170,2841,2987,2210,96,4,835,475,414,64,2414,1511,2732,749,2322,2588,839,174,604,82,26,539,3053,2735,372,757,1524,913,2744,1297,613,1090,2349,61,2616,131,429,199,2817,621,777,697,384,2143,3079,1203,1434,785,2692,1209,2266,1012,6,1015,936,441,1440,1924,1109,218,1327,1813,790,2045,791,638,570,5,1223,2161,949,47,450,1706,1230,513,644,51,2912,1832,1833,310,2176,359
0.2756939090187885,-0.5817669225092277,1.550946556196765,0.08552503374798644,0.9378771015302817,1.3882100669604411,0.1493999725419618,1.657680089871788,-0.04371782774137989,-0.17500271918170665,0.08552503374798644,0.08552503374798644,-0.10910107725747438,-0.10910107725747438,0.021154959123965873,1.3882100669604411,0.6434302553162722,0.6434302553162722,-1.3833236694797724,0.7031636084840797,0.08552503374798644,1.1096416031090883,0.021154959123965873,0.7031636084840797,0.6434302553162722,1.4428130982976093,1.277907963516101,0.40009409100938204,-0.5125776294717194,0.2756939090187885,-0.4439584005973705,0.21278718307129618,-0.9365999560555965,-1.2317465192005141,-0.37590010541019514,1.7105328972774696,6.273729161291968,0.4616012571920667,0.7624690661744893,0.8213525930752211,2.020717946656322,-0.5125776294717194,0.021154959123965873,-0.7928498829766004,0.5226553678023891,-0.4439584005973705,-0.6515356333511229,0.4616012571920667,1.3332432815151989,0.6434302553162722,1.815231903298355,3.111810995117898,0.7031636084840797,-1.3833236694797724,-0.7928498829766004,0.8798200308586908,0.5226553678023891,0.021154959123965873,0.40009409100938204,-0.7928498829766004,0.1493999725419618,0.6434302553162722,0.2756939090187885,-0.4439584005973705,2.1715325399779393,-0.6515356333511229,1.4970570622608441,0.8213525930752211,1.277907963516101,-0.8644153121428026,0.6434302553162722,0.5226553678023891,0.5832629155020134,0.8798200308586908,-0.30839382957997863,-1.460155105498623,0.21278718307129618,0.08552503374798644,0.5226553678023891,-0.7218933461099717,0.21278718307129618,-0.37590010541019514,0.3381272349672459,5.075890701055905,0.3381272349672459,0.40009409100938204,0.8213525930752211,0.08552503374798644,-0.17500271918170665,0.2756939090187885,1.222199240405792,0.1493999725419618,-0.10910107725747438,0.5226553678023891,-0.24143086817602652,0.5226553678023891,0.6434302553162722,0.7031636084840797,5.809318295160335,0.21278718307129618,-0.30839382957997863,0.40009409100938204,2.4168980616095,0.8213525930752211,-0.04371782774137989,0.21278718307129618,0.7624690661744893,0.6434302553162722,2.3196296243830314,-1.009414400019985,-0.10910107725747438,-0.10910107725747438,1.0527824505275314,-0.30839382957997863,0.9378771015302817
3,216