term stringlengths 2 121 | overlap int64 6 281 | setsize int64 7 499 | score float64 1.96 10.6 | pval float64 0 0.05 | edge stringlengths 41 1.97k | type stringclasses 5 values | subtype stringclasses 24 values | subtype_key stringclasses 24 values | edge_idxs stringlengths 11 1.17k | ann_idxs stringlengths 19 2.31k | ann_vals stringlengths 124 9.94k | sig_size int64 2.2k 3.73k |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Organic acid transmembrane transport | 10 | 32 | 2.715049 | 0.006627 | Q9UBX3,O43772,Q96NB2,P30825,P08183,Q9Y619,Q9BQT8,Q9H2D1,P23786,P53985 | Processes and pathways | GO Biological process | msigdb_gobp | 229,68,362,231,273,243,253,188,126,159 | 68,2185,1130,1600,2691,2657,273,1005,439,126,875,231,834,1608,1884,1037,2481,1266,159,555,822,1245,362,253,188,1637,770,1710,1050,229,817,243 | 2.653898835377378,-0.42054478130569956,0.14061496438072402,-0.13400802540056259,-0.7014560751754394,-0.6823259973888944,1.2745171327387752,0.2242105156109122,0.874992360533424,2.0446992086793294,0.32321507233725794,1.3890806941306666,0.3559084044891777,-0.13400802540056259,-0.2578126878849311,0.2075721060916025,-0.5687820738676072,0.05598875083654143,1.7913080821408316,0.6592557088759661,0.37219845949424474,0.07299824094238225,1.0253881251741155,1.3320048573799028,1.6272504471321572,-0.13400802540056259,0.4208452065718874,-0.16914305785560818,0.2075721060916025,1.4032863000627067,0.3884511119152299,1.3605937226731146 | 3,219 |
Primary mitochondrial disease | 30 | 99 | 2.70486 | 0.006833 | O75879,O43676,Q9Y584,O95831,P12235,Q96IX5,Q8NI60,Q6DKK2,Q9BW92,Q86Y39,O75208,P03886,Q5XKP0,O75306,Q70HW3,Q9Y606,Q7KZN9,P00846,P13073,P22695,Q13472,Q9UBX3,Q9Y6M9,Q96CU9,Q9NPL8,Q7LG56,O14949,Q9BQT8,Q5T440,Q99757 | Drugs and Diseases | Protein Atlas Disease involvement | protein_atlas_disease_involvement | 514,7,137,392,393,399,289,163,427,311,438,57,445,190,74,462,335,213,465,223,506,229,238,116,378,500,247,253,381,382 | 2653,247,7,3091,1525,1599,438,799,190,2377,1459,514,1076,1155,392,1156,213,57,1319,1915,2629,393,465,2658,1804,1881,223,2599,3174,1212,2192,2818,1652,2272,2635,2764,3123,1471,1352,1112,2237,1731,506,1412,2245,2888,1332,856,381,1016,445,163,733,74,335,2396,500,311,2127,924,2323,289,1666,2211,926,116,399,2442,2614,382,651,2292,1370,253,1746,928,1516,528,427,811,619,2754,378,1454,1309,1255,1792,2590,229,2813,1756,1340,2410,653,1794,2472,137,462,238 | -0.6823259973888944,1.3320048573799028,4.151275569658641,-1.348931336259688,-0.09905875539476565,-0.13400802540056259,0.874992360533424,0.3884511119152299,1.6134312131752497,-0.5127816595838254,-0.06429240403855782,0.7060156085430525,0.17417480799747104,0.12377336021763811,0.950561610502623,0.12377336021763811,1.5020304740736174,2.7272360837614658,0.02184122951698084,-0.2756922953883126,-0.663255694292154,0.950561610502623,0.8139874535706313,-0.6823259973888944,-0.22220031488448316,-0.2578126878849311,1.4316224032315916,-0.6442446228460273,-2.083758514401128,0.08996530109043266,-0.42054478130569956,-0.8175232899524535,-0.15155214072249368,-0.4572777844322593,-0.663255694292154,-0.7592105127205729,-1.479059046842797,-0.06429240403855782,0.004702563072839793,0.15741534907558857,-0.43888463081271056,-0.1867811438681572,0.7370251408289138,-0.0297061989992813,-0.43888463081271056,-0.8961701064156942,0.02184122951698084,0.3395806940145738,0.9805801487420218,0.2242105156109122,0.859787466513618,1.7777592561307913,0.45309265624254375,2.6046804013362,1.1142289703794899,-0.5127816595838254,0.7524813868036361,1.1582704354775262,-0.3840232035503077,0.2903690579322796,-0.4757246978649692,1.2311257458045275,-0.15155214072249368,-0.42054478130569956,0.2903690579322796,2.175119142227216,0.950561610502623,-0.5313926522763559,-0.6442446228460273,0.9805801487420218,0.548974178419281,-0.4572777844322593,0.004702563072839793,1.3320048573799028,-0.1867811438681572,0.2903690579322796,-0.0816528898016005,0.6904619242239327,0.9053105719493667,0.3884511119152299,0.5806538884509506,-0.7398977686794529,0.9955452840839076,-0.046976953777104945,0.038936518919033984,0.07299824094238225,-0.20446677062676033,-0.6252922481428479,1.4032863000627067,-0.7980226823314418,-0.1867811438681572,0.02184122951698084,-0.5127816595838254,0.548974178419281,-0.20446677062676033,-0.5500592938652186,1.952219165715867,0.8292851967373376,1.3748498787678702 | 3,219 |
Electron transport chain oxphos system in mitochondria | 14 | 56 | 2.703979 | 0.006851 | O75306,O75964,P14406,O43676,Q99643,Q9Y6M9,Q7KZN9,P00846,Q9Y6N1,Q9UDW1,P56134,P03886,O14949,P22695 | Processes and pathways | WikiPathways | msigdb_wp | 190,37,386,7,106,238,335,213,246,256,372,57,247,223 | 2653,687,871,247,2654,7,2736,799,190,2377,1459,1076,1530,37,537,1679,895,1945,1155,1759,1156,213,57,1286,1601,1079,1683,393,1209,465,386,2658,1605,1804,1881,1917,223,1008,2599,3174,1212,1081,1982,2987,2635,671,372,918,2748,1412,335,106,256,1491,238,246 | -0.6823259973888944,0.5011930708427338,0.32321507233725794,1.3320048573799028,-0.6823259973888944,4.151275569658641,-0.7398977686794529,0.3884511119152299,1.6134312131752497,-0.5127816595838254,-0.06429240403855782,0.17417480799747104,-0.09905875539476565,2.9794613003008097,0.6748753590501604,-0.16914305785560818,0.30681128083133596,-0.29362137810344713,0.12377336021763811,-0.20446677062676033,0.12377336021763811,1.5020304740736174,2.7272360837614658,0.038936518919033984,-0.13400802540056259,0.17417480799747104,-0.16914305785560818,0.950561610502623,0.08996530109043266,0.8139874535706313,0.9655856472779832,-0.6823259973888944,-0.13400802540056259,-0.22220031488448316,-0.2578126878849311,-0.2756922953883126,1.4316224032315916,0.2242105156109122,-0.6442446228460273,-2.083758514401128,0.08996530109043266,0.17417480799747104,-0.3116003386120246,-1.0566916417769305,-0.663255694292154,0.517155278900476,0.9955452840839076,0.2903690579322796,-0.7398977686794529,-0.0297061989992813,1.1142289703794899,2.2780713578916147,1.3320048573799028,-0.06429240403855782,1.3748498787678702,1.3463120934073578 | 3,219 |
Receptor | 11 | 37 | 2.684965 | 0.007254 | Q9NS69,Q99720,P24390,O15118,P30825,Q14108,Q8WTV0,O43731,Q9Y2I1,Q14739,O15173 | Functions | Protein Atlas Molecular function | protein_atlas_molecular_function | 67,130,35,131,231,142,16,80,184,56,248 | 257,3216,131,248,80,1152,1430,2657,959,1800,2419,1972,719,1602,491,1466,938,35,231,524,2704,2722,142,56,1245,1173,16,2495,2999,377,2098,130,67,184,1125,1493,956 | 1.3176718798343572,-5.1621017291804545,1.9919755786666307,1.3320048573799028,2.505440145625614,0.12377336021763811,-0.046976953777104945,-0.6823259973888944,0.257368256721385,-0.22220031488448316,-0.5313926522763559,-0.3116003386120246,0.46916199239345446,-0.13400802540056259,0.7679055479970575,-0.06429240403855782,0.27388813909007026,3.1089411622598995,1.3890806941306666,0.6904619242239327,-0.7014560751754394,-0.7206464789962234,1.9256117441147356,2.739402554629938,0.07299824094238225,0.12377336021763811,3.7646475146351115,-0.5687820738676072,-1.0770728414740884,0.9955452840839076,-0.3658405952562187,2.0183777919842116,2.666162311535732,1.6685697660706003,0.15741534907558857,-0.06429240403855782,0.27388813909007026 | 3,219 |
Rna stabilization | 9 | 26 | 2.684651 | 0.007261 | Q13151,Q14011,O60506,P35637,Q92804,Q14103,Q16539,Q08J23,P98175 | Processes and pathways | GO Biological process | msigdb_gobp | 288,192,189,96,136,232,302,336,343 | 189,1429,1797,1033,609,758,96,2388,455,343,1847,1244,336,1140,288,192,232,922,302,1821,698,136,2563,1964,1968,1125 | 1.6134312131752497,-0.046976953777104945,-0.22220031488448316,0.2075721060916025,0.5806538884509506,0.4208452065718874,2.3671810512426905,-0.5127816595838254,0.8445518061819609,1.084728683067828,-0.23998215837100623,0.07299824094238225,1.099492860982002,0.14061496438072402,1.2311257458045275,1.6134312131752497,1.3890806941306666,0.2903690579322796,1.1728958117690913,-0.22220031488448316,0.5011930708427338,1.9654918389860268,-0.6063980432373821,-0.29362137810344713,-0.29362137810344713,0.15741534907558857 | 3,219 |
Abdominal pain | 12 | 82 | 2.681057 | 0.007339 | P35637,P14174,P57740,P42892,P04062,Q70HW3,Q99643,Q03426,Q9NZ08,Q14108,Q13423,P23786 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 96,3,70,102,105,74,106,141,46,142,119,126 | 798,774,1002,1105,105,2381,384,2835,2692,2547,3021,3022,1462,1432,1159,3,540,1917,2340,849,126,3156,1212,1884,2477,743,96,1162,1058,690,691,2911,102,1134,1569,1010,2636,2274,70,1572,2555,2314,1012,168,555,141,836,542,1384,119,661,142,1116,2395,763,1191,838,1735,1222,337,2707,764,74,500,615,414,1778,603,1366,2496,106,1488,2809,2370,1790,46,2072,1393,909,2000,910,1675 | 0.3884511119152299,0.4046666118339641,0.2242105156109122,0.15741534907558857,2.290856236991885,-0.5127816595838254,0.9655856472779832,-0.837087716438348,-0.7014560751754394,-0.6063980432373821,-1.1386554079722488,-1.1386554079722488,-0.06429240403855782,-0.046976953777104945,0.12377336021763811,4.524257799898794,0.6748753590501604,-0.2756922953883126,-0.49422583330773395,0.3395806940145738,2.0446992086793294,-1.8425667734679056,0.08996530109043266,-0.2578126878849311,-0.5687820738676072,0.4369871407324282,2.3671810512426905,0.12377336021763811,0.19089363138798773,0.5011930708427338,0.5011930708427338,-0.9358889993899692,2.329100568036832,0.14061496438072402,-0.11651034953388262,0.2242105156109122,-0.663255694292154,-0.4572777844322593,2.6293226533158274,-0.11651034953388262,-0.6063980432373821,-0.4757246978649692,0.2242105156109122,1.7369806906741143,0.6592557088759661,1.9256117441147356,0.3559084044891777,0.6748753590501604,-0.0124798039226905,2.1361981793017475,0.5330822391938458,1.9256117441147356,0.15741534907558857,-0.5127816595838254,0.4208452065718874,0.10689023937979268,0.3559084044891777,-0.1867811438681572,0.08996530109043266,1.099492860982002,-0.7014560751754394,0.4208452065718874,2.6046804013362,0.7524813868036361,0.5806538884509506,0.9204242461273519,-0.20446677062676033,0.5964421007549159,0.004702563072839793,-0.5687820738676072,2.2780713578916147,-0.06429240403855782,-0.7980226823314418,-0.49422583330773395,-0.20446677062676033,2.836165185919543,-0.3477095307450096,-0.0124798039226905,0.30681128083133596,-0.3116003386120246,0.30681128083133596,-0.15155214072249368 | 3,219 |
Electron transport | 13 | 52 | 2.679361 | 0.007376 | Q6DKK2,O75306,O43169,O43676,Q99643,Q9Y6M9,Q96CU9,Q9Y241,O14949,Q9UDW1,P03886,Q9H1E5,P22695 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 163,190,134,7,106,238,116,181,247,256,57,195,223 | 2653,871,247,134,738,2654,7,2736,799,190,2377,1459,537,1679,895,1945,1155,1834,1759,1156,57,1915,2476,2658,1804,1917,2341,223,3174,1212,1081,2478,2745,2635,671,635,2748,1412,2559,163,311,116,2067,106,382,195,560,1309,1792,256,181,238 | -0.6823259973888944,0.32321507233725794,1.3320048573799028,1.9787439456572407,0.4369871407324282,-0.6823259973888944,4.151275569658641,-0.7398977686794529,0.3884511119152299,1.6134312131752497,-0.5127816595838254,-0.06429240403855782,0.6748753590501604,-0.16914305785560818,0.30681128083133596,-0.29362137810344713,0.12377336021763811,-0.23998215837100623,-0.20446677062676033,0.12377336021763811,2.7272360837614658,-0.2756922953883126,-0.5687820738676072,-0.6823259973888944,-0.22220031488448316,-0.2756922953883126,-0.49422583330773395,1.4316224032315916,-2.083758514401128,0.08996530109043266,0.17417480799747104,-0.5687820738676072,-0.7398977686794529,-0.663255694292154,0.517155278900476,0.564831320865879,-0.7398977686794529,-0.0297061989992813,-0.6063980432373821,1.7777592561307913,1.1582704354775262,2.175119142227216,-0.3477095307450096,2.2780713578916147,0.9805801487420218,1.6134312131752497,0.6592557088759661,0.038936518919033984,-0.20446677062676033,1.3320048573799028,1.69600177785008,1.3748498787678702 | 3,219 |
Respiratory chain | 10 | 36 | 2.669311 | 0.007601 | Q6DKK2,O75306,O43676,Q9Y6M9,Q96CU9,Q9Y241,Q9UDW1,P03886,O14949,P22695 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 163,190,7,238,116,181,256,57,247,223 | 2653,871,247,2654,7,2736,799,190,2377,1459,537,1679,895,1945,1155,1759,1156,57,1915,2658,1804,223,3174,1081,2635,671,2748,1412,163,311,116,1309,1792,256,181,238 | -0.6823259973888944,0.32321507233725794,1.3320048573799028,-0.6823259973888944,4.151275569658641,-0.7398977686794529,0.3884511119152299,1.6134312131752497,-0.5127816595838254,-0.06429240403855782,0.6748753590501604,-0.16914305785560818,0.30681128083133596,-0.29362137810344713,0.12377336021763811,-0.20446677062676033,0.12377336021763811,2.7272360837614658,-0.2756922953883126,-0.6823259973888944,-0.22220031488448316,1.4316224032315916,-2.083758514401128,0.17417480799747104,-0.663255694292154,0.517155278900476,-0.7398977686794529,-0.0297061989992813,1.7777592561307913,1.1582704354775262,2.175119142227216,0.038936518919033984,-0.20446677062676033,1.3320048573799028,1.69600177785008,1.3748498787678702 | 3,219 |
Alcohol metabolic process | 24 | 90 | 2.669279 | 0.007601 | Q9UBM7,O15118,Q9BY49,P35270,Q03426,Q8WTV0,P00374,P48735,P54646,Q15800,Q13510,Q6NUM9,Q14739,Q15392,Q16822,Q9H2C2,Q86SQ9,O75874,Q10713,Q16850,Q6P1A2,O15269,P04062,Q9BQE5 | Processes and pathways | GO Biological process | msigdb_gobp | 391,131,389,9,141,16,145,23,278,29,419,303,56,61,65,326,446,69,456,76,204,473,105,125 | 3103,131,473,892,2037,2005,2737,2415,894,69,1564,2041,2380,145,2474,105,936,1004,3012,1159,1106,1836,2882,937,915,2270,2341,759,1133,9,1533,1325,2873,760,642,23,1984,2162,778,2273,2701,475,2085,278,3089,1891,1329,2671,2998,2278,141,456,419,3070,1576,2576,1617,56,2524,515,2464,61,2804,29,65,76,303,204,446,1663,990,2492,16,2586,2999,3018,2500,125,1303,389,326,2983,1965,1638,582,727,391,2298,753,3077 | -1.391961876631989,1.9919755786666307,0.7986583902396478,0.30681128083133596,-0.3477095307450096,-0.3296295849566747,-0.7398977686794529,-0.5313926522763559,0.30681128083133596,2.6416189707121984,-0.11651034953388262,-0.3477095307450096,-0.5127816595838254,1.9122768063716753,-0.5687820738676072,2.290856236991885,0.27388813909007026,0.2242105156109122,-1.1180539551826354,0.12377336021763811,0.15741534907558857,-0.23998215837100623,-0.8961701064156942,0.27388813909007026,0.2903690579322796,-0.4572777844322593,-0.49422583330773395,0.4208452065718874,0.14061496438072402,3.991922687702279,-0.09905875539476565,0.02184122951698084,-0.8764104949654021,0.4208452065718874,0.548974178419281,3.3628016428383716,-0.3116003386120246,-0.4022577865800413,0.4046666118339641,-0.4572777844322593,-0.7014560751754394,0.7986583902396478,-0.3658405952562187,1.2600798177392025,-1.3275421151096782,-0.2578126878849311,0.02184122951698084,-0.6823259973888944,-1.0770728414740884,-0.4572777844322593,1.9256117441147356,0.8445518061819609,0.9053105719493667,-1.285011033296226,-0.11651034953388262,-0.6252922481428479,-0.13400802540056259,2.739402554629938,-0.5875614889822378,0.7060156085430525,-0.5500592938652186,2.6906403531600036,-0.7980226823314418,3.2366995159470866,2.666162311535732,2.579971557206447,1.1728958117690913,1.5579205959049545,0.859787466513618,-0.15155214072249368,0.240809140160788,-0.5687820738676072,3.7646475146351115,-0.6252922481428479,-1.0770728414740884,-1.1180539551826354,-0.5687820738676072,2.0578298433871516,0.038936518919033984,0.9655856472779832,1.1289371667707588,-1.0363823429612895,-0.29362137810344713,-0.13400802540056259,0.627916326361481,0.46916199239345446,0.9655856472779832,-0.4572777844322593,0.4369871407324282,-1.285011033296226 | 3,219 |
Mitochondrial protein import | 14 | 36 | 2.66869 | 0.007615 | O60830,Q8N4H5,Q9NS69,Q5JRX3,Q10713,P21796,Q15388,P12235,Q9Y584,Q9Y5J6,O14925,Q99595,Q9Y5J9,P62072 | Processes and pathways | Reactome Pathways | msigdb_reactome | 32,648,67,577,456,6,420,393,137,173,111,48,585,187 | 111,975,32,2759,1913,1260,1130,848,873,1601,1915,2778,393,1209,6,2599,2698,778,187,456,645,420,1579,577,648,48,2500,2099,67,1123,817,2813,828,137,173,585 | 2.2138676701946065,0.240809140160788,3.1788366810455857,-0.7592105127205729,-0.2756922953883126,0.05598875083654143,0.14061496438072402,0.3395806940145738,0.32321507233725794,-0.13400802540056259,-0.2756922953883126,-0.7785852884708848,0.950561610502623,0.08996530109043266,4.19336581363514,-0.6442446228460273,-0.7014560751754394,0.4046666118339641,1.6272504471321572,0.8445518061819609,0.548974178419281,0.9053105719493667,-0.11651034953388262,0.627916326361481,0.548974178419281,2.7999968682905996,-0.5687820738676072,-0.3658405952562187,2.666162311535732,0.15741534907558857,0.3884511119152299,-0.7980226823314418,0.37219845949424474,1.952219165715867,1.7233434559929421,0.627916326361481 | 3,219 |
Alcohol biosynthetic process | 16 | 41 | 2.668635 | 0.007616 | O15269,Q9UBM7,Q16822,Q9H2C2,Q86SQ9,P35270,P04062,Q13510,Q03426,Q6P1A2,Q16850,P00374,Q15392,P54646,Q14739,Q15800 | Processes and pathways | GO Biological process | msigdb_gobp | 473,391,65,326,446,9,105,419,141,204,76,145,61,278,56,29 | 3103,473,892,2415,894,2041,145,2474,105,3012,1159,1836,915,2270,9,1325,2873,642,2085,278,1891,2998,141,419,2576,56,515,2464,61,2804,29,65,76,204,446,2999,3018,326,1638,582,391 | -1.391961876631989,0.7986583902396478,0.30681128083133596,-0.5313926522763559,0.30681128083133596,-0.3477095307450096,1.9122768063716753,-0.5687820738676072,2.290856236991885,-1.1180539551826354,0.12377336021763811,-0.23998215837100623,0.2903690579322796,-0.4572777844322593,3.991922687702279,0.02184122951698084,-0.8764104949654021,0.548974178419281,-0.3658405952562187,1.2600798177392025,-0.2578126878849311,-1.0770728414740884,1.9256117441147356,0.9053105719493667,-0.6252922481428479,2.739402554629938,0.7060156085430525,-0.5500592938652186,2.6906403531600036,-0.7980226823314418,3.2366995159470866,2.666162311535732,2.579971557206447,1.5579205959049545,0.859787466513618,-1.0770728414740884,-1.1180539551826354,1.1289371667707588,-0.13400802540056259,0.627916326361481,0.9655856472779832 | 3,219 |
Blindness | 18 | 77 | 2.665614 | 0.007685 | O43505,O75306,Q86SQ9,O43676,Q15555,P06865,Q9Y6M9,Q9NZ08,Q9H6K4,P07602,Q86Y39,Q96CU9,P00846,P50897,Q9NPL8,P03886,P51798,Q8NHS3 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 153,190,446,7,457,330,238,46,14,112,311,116,213,22,378,57,380,193 | 890,1943,2715,153,7,2005,1129,799,190,2377,1459,2302,2378,1759,2969,213,57,2597,2741,330,112,2692,1319,2042,1802,705,1804,1917,2341,3174,1212,1650,1884,2477,1435,1887,1009,1569,851,2635,2162,22,380,821,467,2785,1817,1139,2637,2638,457,1479,2397,446,311,2466,924,193,1666,991,1781,1275,116,1368,617,2845,1516,14,3136,378,594,1309,46,795,1255,1969,238 | 0.30681128083133596,-0.29362137810344713,-0.7206464789962234,1.845285994530105,4.151275569658641,-0.3296295849566747,0.14061496438072402,0.3884511119152299,1.6134312131752497,-0.5127816595838254,-0.06429240403855782,-0.4757246978649692,-0.5127816595838254,-0.20446677062676033,-1.0161442081118819,1.5020304740736174,2.7272360837614658,-0.6442446228460273,-0.7398977686794529,1.1142289703794899,2.2138676701946065,-0.7014560751754394,0.02184122951698084,-0.3477095307450096,-0.22220031488448316,0.4851953858805861,-0.22220031488448316,-0.2756922953883126,-0.49422583330773395,-2.083758514401128,0.08996530109043266,-0.15155214072249368,-0.2578126878849311,-0.5687820738676072,-0.046976953777104945,-0.2578126878849311,0.2242105156109122,-0.11651034953388262,0.3395806940145738,-0.663255694292154,-0.4022577865800413,3.5768907333196704,0.9805801487420218,0.37219845949424474,0.8139874535706313,-0.7785852884708848,-0.22220031488448316,0.14061496438072402,-0.663255694292154,-0.663255694292154,0.8445518061819609,-0.06429240403855782,-0.5127816595838254,0.859787466513618,1.1582704354775262,-0.5500592938652186,0.2903690579322796,1.6134312131752497,-0.15155214072249368,0.240809140160788,-0.20446677062676033,0.05598875083654143,2.175119142227216,0.004702563072839793,0.5806538884509506,-0.837087716438348,-0.0816528898016005,3.8734982338727697,-1.567593340775535,0.9955452840839076,0.6121961750555308,0.038936518919033984,2.836165185919543,0.4046666118339641,0.07299824094238225,-0.29362137810344713,1.3748498787678702 | 3,219 |
Abnormal brainstem mri signal intensity | 7 | 22 | 2.654668 | 0.007939 | O75306,O43676,Q9Y6M9,Q86Y39,Q9NPL8,Q96CU9,P03886 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 190,7,238,311,378,116,57 | 7,799,190,2377,1459,392,1759,57,1804,3174,1164,2635,311,924,1666,926,116,1516,378,1309,1255,238 | 4.151275569658641,0.3884511119152299,1.6134312131752497,-0.5127816595838254,-0.06429240403855782,0.950561610502623,-0.20446677062676033,2.7272360837614658,-0.22220031488448316,-2.083758514401128,0.12377336021763811,-0.663255694292154,1.1582704354775262,0.2903690579322796,-0.15155214072249368,0.2903690579322796,2.175119142227216,-0.0816528898016005,0.9955452840839076,0.038936518919033984,0.07299824094238225,1.3748498787678702 | 3,219 |
Dysphagia | 29 | 136 | 2.652539 | 0.007989 | Q9UHX1,Q99720,O15118,P07737,P12235,O76024,Q14108,P48735,O94830,Q8N0X7,Q13510,Q06787,Q9NR77,Q14739,P03886,Q6Y7W6,O75306,O75874,Q9Y5Y5,Q15233,P00846,Q15067,Q8IZA0,P35637,P04062,Q99643,P07602,Q01105,Q7LG56 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 1,130,131,385,393,264,142,23,410,295,419,434,49,56,57,310,190,69,197,469,213,216,90,96,105,106,112,375,500 | 1029,2733,1562,131,2144,1525,1599,190,1459,1678,69,1564,264,410,2041,777,757,2379,2880,2337,213,57,105,897,936,1879,112,385,1799,3022,3012,2042,1603,393,801,1263,2513,2079,1323,1917,2113,3174,833,3156,1212,1884,96,2572,2515,805,2818,2160,670,23,2701,1266,1571,2115,1380,1728,1654,1241,2785,1329,2013,919,2605,3033,1951,375,633,2799,2428,1114,1893,434,2239,964,1140,506,419,142,1189,2430,3117,2724,56,216,1700,469,1412,2707,310,500,1508,90,295,924,647,2323,677,2494,1299,2023,2095,1707,2614,2966,106,2845,130,652,1370,1708,1516,1824,907,2752,2253,1710,1451,49,886,795,1312,2448,1427,717,1,1938,2259,1756,653,2182,999,197 | 0.2075721060916025,-0.7398977686794529,-0.11651034953388262,1.9919755786666307,-0.4022577865800413,-0.09905875539476565,-0.13400802540056259,1.6134312131752497,-0.06429240403855782,-0.16914305785560818,2.6416189707121984,-0.11651034953388262,1.3033130248343696,0.9204242461273519,-0.3477095307450096,0.4046666118339641,0.4208452065718874,-0.5127816595838254,-0.8961701064156942,-0.49422583330773395,1.5020304740736174,2.7272360837614658,2.290856236991885,0.30681128083133596,0.27388813909007026,-0.2578126878849311,2.2138676701946065,0.9655856472779832,-0.22220031488448316,-1.1386554079722488,-1.1180539551826354,-0.3477095307450096,-0.13400802540056259,0.950561610502623,0.3884511119152299,0.05598875083654143,-0.5875614889822378,-0.3658405952562187,0.02184122951698084,-0.2756922953883126,-0.3840232035503077,-2.083758514401128,0.3559084044891777,-1.8425667734679056,0.08996530109043266,-0.2578126878849311,2.3671810512426905,-0.6252922481428479,-0.5875614889822378,0.3884511119152299,-0.8175232899524535,-0.4022577865800413,0.517155278900476,3.3628016428383716,-0.7014560751754394,0.05598875083654143,-0.11651034953388262,-0.3840232035503077,-0.0124798039226905,-0.1867811438681572,-0.15155214072249368,0.07299824094238225,-0.7785852884708848,0.02184122951698084,-0.3296295849566747,0.2903690579322796,-0.6442446228460273,-1.159331839849001,-0.29362137810344713,0.9955452840839076,0.564831320865879,-0.7980226823314418,-0.5313926522763559,0.15741534907558857,-0.2578126878849311,0.8901666692591385,-0.43888463081271056,0.257368256721385,0.14061496438072402,0.7370251408289138,0.9053105719493667,1.9256117441147356,0.10689023937979268,-0.5313926522763559,-1.4571526976673133,-0.7206464789962234,2.739402554629938,1.4598592164393882,-0.16914305785560818,0.8139874535706313,-0.0297061989992813,-0.7014560751754394,1.1582704354775262,0.7524813868036361,-0.0816528898016005,2.417703668148951,1.2166087034830142,0.2903690579322796,0.548974178419281,-0.4757246978649692,0.517155278900476,-0.5687820738676072,0.038936518919033984,-0.3296295849566747,-0.3658405952562187,-0.16914305785560818,-0.6442446228460273,-0.9959765127527764,2.2780713578916147,-0.837087716438348,2.0183777919842116,0.548974178419281,0.004702563072839793,-0.16914305785560818,-0.0816528898016005,-0.22220031488448316,0.30681128083133596,-0.7398977686794529,-0.43888463081271056,-0.16914305785560818,-0.046976953777104945,2.7879095428710334,0.32321507233725794,0.4046666118339641,0.038936518919033984,-0.5313926522763559,-0.0297061989992813,0.4851953858805861,5.876223836886106,-0.2756922953883126,-0.43888463081271056,-0.1867811438681572,0.548974178419281,-0.4022577865800413,0.240809140160788,1.5995887263604394 | 3,219 |
FDA approved drug targets | 24 | 119 | 2.650313 | 0.008042 | Q99720,P62942,P12235,P00374,P54646,P48735,P49354,P49721,P49356,Q13509,Q9Y2I1,P03886,P28074,O75874,P36404,Q9NRF9,P20618,Q16850,P38435,P00813,P98194,Q16836,Q13423,P23786 | Functions | Protein Atlas Protein class | protein_atlas_protein_class | 130,387,393,145,278,23,24,28,39,292,184,57,317,69,198,201,75,76,332,341,374,113,119,126 | 2335,2957,69,1399,1834,1206,145,667,2894,2337,341,1430,57,1722,2740,571,1078,936,1004,1286,2657,2078,2870,831,2853,2630,2338,1682,2631,2693,1496,393,1209,1287,2779,2854,874,2111,1836,1466,937,1107,1007,75,938,1976,3049,3129,2340,2112,1210,126,1211,1978,2043,2008,317,1686,2836,2796,2157,2662,1212,1185,1650,1533,198,2572,332,1888,2911,1725,2979,23,1569,24,39,28,2162,2481,2085,1165,278,1380,3079,387,1011,374,1987,2575,1816,2788,1217,119,2802,292,2317,468,1617,1989,2059,1245,635,403,2432,113,76,2559,500,747,2093,1932,617,2845,130,1637,3001,201,184 | -0.49422583330773395,-0.9959765127527764,2.6416189707121984,-0.0297061989992813,-0.23998215837100623,0.08996530109043266,1.9122768063716753,0.517155278900476,-0.9159960560023168,-0.49422583330773395,1.084728683067828,-0.046976953777104945,2.7272360837614658,-0.1867811438681572,-0.7398977686794529,0.627916326361481,0.17417480799747104,0.27388813909007026,0.2242105156109122,0.038936518919033984,-0.6823259973888944,-0.3658405952562187,-0.8764104949654021,0.3559084044891777,-0.856716576558732,-0.663255694292154,-0.49422583330773395,-0.16914305785560818,-0.663255694292154,-0.7014560751754394,-0.0816528898016005,0.950561610502623,0.08996530109043266,0.038936518919033984,-0.7785852884708848,-0.856716576558732,0.32321507233725794,-0.3840232035503077,-0.23998215837100623,-0.06429240403855782,0.27388813909007026,0.15741534907558857,0.2242105156109122,2.592334336196873,0.27388813909007026,-0.3116003386120246,-1.200912870498824,-1.5231422110485722,-0.49422583330773395,-0.3840232035503077,0.08996530109043266,2.0446992086793294,0.08996530109043266,-0.3116003386120246,-0.3477095307450096,-0.3296295849566747,1.143617604242851,-0.16914305785560818,-0.837087716438348,-0.7980226823314418,-0.4022577865800413,-0.6823259973888944,0.08996530109043266,0.10689023937979268,-0.15155214072249368,-0.09905875539476565,1.5857228718739784,-0.6252922481428479,1.1142289703794899,-0.2578126878849311,-0.9358889993899692,-0.1867811438681572,-1.0363823429612895,3.3628016428383716,-0.11651034953388262,3.3628016428383716,2.943840788438515,3.2597485190360773,-0.4022577865800413,-0.5687820738676072,-0.3658405952562187,0.12377336021763811,1.2600798177392025,-0.0124798039226905,-1.306235657380079,0.9655856472779832,0.2242105156109122,0.9955452840839076,-0.3116003386120246,-0.6252922481428479,-0.22220031488448316,-0.7785852884708848,0.08996530109043266,2.1361981793017475,-0.7980226823314418,1.2166087034830142,-0.4757246978649692,0.8139874535706313,-0.13400802540056259,-0.3116003386120246,-0.3477095307450096,0.07299824094238225,0.564831320865879,0.9355078676043538,-0.5313926522763559,2.2138676701946065,2.579971557206447,-0.6063980432373821,0.7524813868036361,0.4369871407324282,-0.3658405952562187,-0.2756922953883126,0.5806538884509506,-0.837087716438348,2.0183777919842116,-0.13400802540056259,-1.0770728414740884,1.571833533959058,1.6685697660706003 | 3,219 |
FDA approved drug targets | 24 | 119 | 2.650313 | 0.008042 | Q99720,P62942,P12235,P00374,P54646,P48735,P49354,P49721,P49356,Q13509,Q9Y2I1,P03886,P28074,O75874,P36404,Q9NRF9,P20618,Q16850,P38435,P00813,P98194,Q16836,Q13423,P23786 | Drugs and Diseases | Protein Atlas Disease involvement | protein_atlas_disease_involvement | 130,387,393,145,278,23,24,28,39,292,184,57,317,69,198,201,75,76,332,341,374,113,119,126 | 2335,2957,69,1399,1834,1206,145,667,2894,2337,341,1430,57,1722,2740,571,1078,936,1004,1286,2657,2078,2870,831,2853,2630,2338,1682,2631,2693,1496,393,1209,1287,2779,2854,874,2111,1836,1466,937,1107,1007,75,938,1976,3049,3129,2340,2112,1210,126,1211,1978,2043,2008,317,1686,2836,2796,2157,2662,1212,1185,1650,1533,198,2572,332,1888,2911,1725,2979,23,1569,24,39,28,2162,2481,2085,1165,278,1380,3079,387,1011,374,1987,2575,1816,2788,1217,119,2802,292,2317,468,1617,1989,2059,1245,635,403,2432,113,76,2559,500,747,2093,1932,617,2845,130,1637,3001,201,184 | -0.49422583330773395,-0.9959765127527764,2.6416189707121984,-0.0297061989992813,-0.23998215837100623,0.08996530109043266,1.9122768063716753,0.517155278900476,-0.9159960560023168,-0.49422583330773395,1.084728683067828,-0.046976953777104945,2.7272360837614658,-0.1867811438681572,-0.7398977686794529,0.627916326361481,0.17417480799747104,0.27388813909007026,0.2242105156109122,0.038936518919033984,-0.6823259973888944,-0.3658405952562187,-0.8764104949654021,0.3559084044891777,-0.856716576558732,-0.663255694292154,-0.49422583330773395,-0.16914305785560818,-0.663255694292154,-0.7014560751754394,-0.0816528898016005,0.950561610502623,0.08996530109043266,0.038936518919033984,-0.7785852884708848,-0.856716576558732,0.32321507233725794,-0.3840232035503077,-0.23998215837100623,-0.06429240403855782,0.27388813909007026,0.15741534907558857,0.2242105156109122,2.592334336196873,0.27388813909007026,-0.3116003386120246,-1.200912870498824,-1.5231422110485722,-0.49422583330773395,-0.3840232035503077,0.08996530109043266,2.0446992086793294,0.08996530109043266,-0.3116003386120246,-0.3477095307450096,-0.3296295849566747,1.143617604242851,-0.16914305785560818,-0.837087716438348,-0.7980226823314418,-0.4022577865800413,-0.6823259973888944,0.08996530109043266,0.10689023937979268,-0.15155214072249368,-0.09905875539476565,1.5857228718739784,-0.6252922481428479,1.1142289703794899,-0.2578126878849311,-0.9358889993899692,-0.1867811438681572,-1.0363823429612895,3.3628016428383716,-0.11651034953388262,3.3628016428383716,2.943840788438515,3.2597485190360773,-0.4022577865800413,-0.5687820738676072,-0.3658405952562187,0.12377336021763811,1.2600798177392025,-0.0124798039226905,-1.306235657380079,0.9655856472779832,0.2242105156109122,0.9955452840839076,-0.3116003386120246,-0.6252922481428479,-0.22220031488448316,-0.7785852884708848,0.08996530109043266,2.1361981793017475,-0.7980226823314418,1.2166087034830142,-0.4757246978649692,0.8139874535706313,-0.13400802540056259,-0.3116003386120246,-0.3477095307450096,0.07299824094238225,0.564831320865879,0.9355078676043538,-0.5313926522763559,2.2138676701946065,2.579971557206447,-0.6063980432373821,0.7524813868036361,0.4369871407324282,-0.3658405952562187,-0.2756922953883126,0.5806538884509506,-0.837087716438348,2.0183777919842116,-0.13400802540056259,-1.0770728414740884,1.571833533959058,1.6685697660706003 | 3,219 |
Mitochondrial protein containing complex | 35 | 164 | 2.649994 | 0.008049 | Q9Y291,Q9H4I9,P14406,P21796,O43676,Q9NQ50,Q9Y584,P12235,Q96IX5,Q7Z7F7,O60830,O75964,Q15388,Q9Y5J6,Q99595,Q86Y39,O00411,Q567V2,P40939,P03886,P62072,Q9NS69,O75306,Q9BRJ2,P00846,Q9BYD1,P22695,P56134,Q99643,Q9Y6M9,O14925,Q96CU9,Q9UDW1,Q9NVS2,O14949 | Localization | GO Cellular component | msigdb_gocc | 0,390,386,6,7,263,137,393,399,157,32,37,420,173,48,311,305,180,432,57,187,67,190,339,213,86,223,372,106,238,111,116,256,255,247 | 1376,305,2653,687,871,111,247,1317,2654,7,2005,2736,32,799,190,2377,1913,1459,1530,37,2417,848,537,1679,895,1945,1155,1759,873,1156,213,57,1286,1601,1319,1915,2629,1801,1079,2188,1683,1760,393,1209,465,386,2658,1605,1804,1881,6,1917,223,1008,2599,3174,2662,1212,1081,1609,1982,2698,432,2987,1689,2635,2162,806,778,671,3123,1471,2945,372,2765,918,187,1352,1892,3033,1846,2349,1112,1501,1353,1115,3177,645,2558,2059,420,2641,2748,1412,1478,1579,2245,180,1331,445,1174,785,2396,1930,157,2020,311,1069,2288,600,648,2971,724,2211,2130,904,116,3006,2066,2534,399,3175,48,2098,106,2845,1421,339,593,1590,86,1963,3043,684,390,2754,2099,843,813,606,263,2876,67,815,255,1593,1309,1123,1310,1102,1792,256,2813,0,1756,2410,3045,1794,999,828,137,173,585,238 | -0.0124798039226905,1.1582704354775262,-0.6823259973888944,0.5011930708427338,0.32321507233725794,2.2138676701946065,1.3320048573799028,0.02184122951698084,-0.6823259973888944,4.151275569658641,-0.3296295849566747,-0.7398977686794529,3.1788366810455857,0.3884511119152299,1.6134312131752497,-0.5127816595838254,-0.2756922953883126,-0.06429240403855782,-0.09905875539476565,2.9794613003008097,-0.5313926522763559,0.3395806940145738,0.6748753590501604,-0.16914305785560818,0.30681128083133596,-0.29362137810344713,0.12377336021763811,-0.20446677062676033,0.32321507233725794,0.12377336021763811,1.5020304740736174,2.7272360837614658,0.038936518919033984,-0.13400802540056259,0.02184122951698084,-0.2756922953883126,-0.663255694292154,-0.22220031488448316,0.17417480799747104,-0.42054478130569956,-0.16914305785560818,-0.20446677062676033,0.950561610502623,0.08996530109043266,0.8139874535706313,0.9655856472779832,-0.6823259973888944,-0.13400802540056259,-0.22220031488448316,-0.2578126878849311,4.19336581363514,-0.2756922953883126,1.4316224032315916,0.2242105156109122,-0.6442446228460273,-2.083758514401128,-0.6823259973888944,0.08996530109043266,0.17417480799747104,-0.13400802540056259,-0.3116003386120246,-0.7014560751754394,0.8901666692591385,-1.0566916417769305,-0.16914305785560818,-0.663255694292154,-0.4022577865800413,0.3884511119152299,0.4046666118339641,0.517155278900476,-1.479059046842797,-0.06429240403855782,-0.9758785445560134,0.9955452840839076,-0.7592105127205729,0.2903690579322796,1.6272504471321572,0.004702563072839793,-0.2578126878849311,-1.159331839849001,-0.23998215837100623,-0.49422583330773395,0.15741534907558857,-0.0816528898016005,0.004702563072839793,0.15741534907558857,-2.1085474406996823,0.548974178419281,-0.6063980432373821,-0.3477095307450096,0.9053105719493667,-0.663255694292154,-0.7398977686794529,-0.0297061989992813,-0.06429240403855782,-0.11651034953388262,-0.43888463081271056,1.69600177785008,0.02184122951698084,0.859787466513618,0.12377336021763811,0.4046666118339641,-0.5127816595838254,-0.2756922953883126,1.8318239214365153,-0.3296295849566747,1.1582704354775262,0.19089363138798773,-0.4572777844322593,0.5964421007549159,0.548974178419281,-1.0161442081118819,0.46916199239345446,-0.42054478130569956,-0.3840232035503077,0.30681128083133596,2.175119142227216,-1.0975266917077975,-0.3477095307450096,-0.5875614889822378,0.950561610502623,-2.083758514401128,2.7999968682905996,-0.3658405952562187,2.2780713578916147,-0.837087716438348,-0.0297061989992813,1.099492860982002,0.6121961750555308,-0.11651034953388262,2.455409687353435,-0.29362137810344713,-1.1800840546241298,0.517155278900476,0.9655856472779832,-0.7398977686794529,-0.3658405952562187,0.3559084044891777,0.3884511119152299,0.5964421007549159,1.3176718798343572,-0.8764104949654021,2.666162311535732,0.3884511119152299,1.3320048573799028,-0.11651034953388262,0.038936518919033984,0.15741534907558857,0.038936518919033984,0.17417480799747104,-0.20446677062676033,1.3320048573799028,-0.7980226823314418,6.011333335192922,-0.1867811438681572,-0.5127816595838254,-1.1800840546241298,-0.20446677062676033,0.240809140160788,0.37219845949424474,1.952219165715867,1.7233434559929421,0.627916326361481,1.3748498787678702 | 3,219 |
Organic anion transmembrane transporter activity | 11 | 31 | 2.642489 | 0.00823 | Q9UBX3,Q96NB2,P30825,P12235,Q9BQT8,Q9Y619,O00400,Q9Y6M7,Q9H2D1,Q8TB61,P53985 | Functions | GO Molecular function | msigdb_gomf | 229,362,231,393,253,243,54,417,188,158,159 | 54,2906,2625,1130,2691,1286,1005,439,393,1209,231,1037,1266,159,555,3173,1245,1295,1548,158,362,253,188,1637,1710,1050,1120,229,817,243,417 | 2.7515530751583857,-0.9358889993899692,-0.663255694292154,0.14061496438072402,-0.7014560751754394,0.038936518919033984,0.2242105156109122,0.874992360533424,0.950561610502623,0.08996530109043266,1.3890806941306666,0.2075721060916025,0.05598875083654143,1.7913080821408316,0.6592557088759661,-2.059096766572429,0.07299824094238225,0.038936518919033984,-0.09905875539476565,1.8183403125254671,1.0253881251741155,1.3320048573799028,1.6272504471321572,-0.13400802540056259,-0.16914305785560818,0.2075721060916025,0.15741534907558857,1.4032863000627067,0.3884511119152299,1.3605937226731146,0.9204242461273519 | 3,219 |
Peptide binding | 18 | 71 | 2.637326 | 0.008356 | Q9Y287,P24390,Q6P179,P42892,O00264,Q15388,Q9Y584,Q9NQX7,P10321,P55786,Q9NZ08,Q8WTV0,O43731,Q03518,P50542,O43813,Q15392,Q9UIQ6 | Functions | GO Molecular function | msigdb_gomf | 161,35,262,102,257,420,137,488,459,138,46,16,80,240,498,463,61,95 | 2732,257,1104,1316,570,2734,80,463,1128,933,2006,848,1184,1880,1320,459,1466,1467,2420,35,2156,1161,2662,804,2855,1534,2573,1083,102,2979,2346,1164,498,692,1890,673,138,2555,2519,693,2197,240,1772,2239,2720,1851,1856,3081,420,61,262,1955,16,699,2497,1145,2648,1862,3000,1277,2253,866,488,2257,46,512,1714,95,161,1643,137 | -0.7398977686794529,1.3176718798343572,0.15741534907558857,0.02184122951698084,0.627916326361481,-0.7398977686794529,2.505440145625614,0.8139874535706313,0.14061496438072402,0.27388813909007026,-0.3296295849566747,0.3395806940145738,0.10689023937979268,-0.2578126878849311,0.02184122951698084,0.8292851967373376,-0.06429240403855782,-0.06429240403855782,-0.5313926522763559,3.1089411622598995,-0.4022577865800413,0.12377336021763811,-0.6823259973888944,0.3884511119152299,-0.856716576558732,-0.09905875539476565,-0.6252922481428479,0.17417480799747104,2.329100568036832,-1.0363823429612895,-0.49422583330773395,0.12377336021763811,0.7524813868036361,0.5011930708427338,-0.2578126878849311,0.517155278900476,1.938925832208026,-0.6063980432373821,-0.5875614889822378,0.5011930708427338,-0.42054478130569956,1.3605937226731146,-0.20446677062676033,-0.43888463081271056,-0.7206464789962234,-0.23998215837100623,-0.23998215837100623,-1.306235657380079,0.9053105719493667,2.6906403531600036,1.3176718798343572,-0.29362137810344713,3.7646475146351115,0.5011930708427338,-0.5687820738676072,0.14061496438072402,-0.663255694292154,-0.23998215837100623,-1.0770728414740884,0.05598875083654143,-0.43888463081271056,0.3395806940145738,0.7832978184435848,-0.43888463081271056,2.836165185919543,0.7215366140730911,-0.16914305785560818,2.3924780208335688,1.7913080821408316,-0.13400802540056259,1.952219165715867 | 3,219 |
secondary carrier transporter | 6 | 15 | 2.633965 | 0.008439 | Q9UBX3,Q96H78,Q9Y6M7,O00400,Q9BQT8,Q8TB61 | Functions | Panther Protein class | panther_protein_class | 229,11,417,54,253,158 | 54,1030,1130,1131,1380,555,1548,158,726,11,253,1710,229,817,417 | 2.7515530751583857,0.2075721060916025,0.14061496438072402,0.14061496438072402,-0.0124798039226905,0.6592557088759661,-0.09905875539476565,1.8183403125254671,0.46916199239345446,3.959758868615795,1.3320048573799028,-0.16914305785560818,1.4032863000627067,0.3884511119152299,0.9204242461273519 | 3,219 |
Steroid metabolism | 9 | 29 | 2.632011 | 0.008488 | O15118,Q9H2C2,P04062,Q16850,Q03426,Q15392,P54646,Q14739,Q15800 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 131,326,105,76,141,61,278,56,29 | 131,2415,894,1564,2041,2474,105,1836,2341,1533,1325,278,1329,2671,2998,141,2576,56,515,2464,61,2804,29,76,2845,326,391,2298,1936 | 1.9919755786666307,-0.5313926522763559,0.30681128083133596,-0.11651034953388262,-0.3477095307450096,-0.5687820738676072,2.290856236991885,-0.23998215837100623,-0.49422583330773395,-0.09905875539476565,0.02184122951698084,1.2600798177392025,0.02184122951698084,-0.6823259973888944,-1.0770728414740884,1.9256117441147356,-0.6252922481428479,2.739402554629938,0.7060156085430525,-0.5500592938652186,2.6906403531600036,-0.7980226823314418,3.2366995159470866,2.579971557206447,-0.837087716438348,1.1289371667707588,0.9655856472779832,-0.4572777844322593,-0.2756922953883126 | 3,219 |
Arthralgia | 8 | 30 | 2.627498 | 0.008602 | Q96HY6,P28070,P14174,P06280,Q13510,Q03426,Q9NZ08,Q15800 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 424,260,3,384,419,141,46,29 | 774,1105,1719,2268,384,3,1566,2152,1840,849,260,2477,743,1569,2194,1728,2314,1730,141,419,1191,29,2496,424,494,46,1557,2000,1970,910 | 0.4046666118339641,0.15741534907558857,-0.1867811438681572,-0.4572777844322593,0.9655856472779832,4.524257799898794,-0.11651034953388262,-0.4022577865800413,-0.23998215837100623,0.3395806940145738,1.3176718798343572,-0.5687820738676072,0.4369871407324282,-0.11651034953388262,-0.42054478130569956,-0.1867811438681572,-0.4757246978649692,-0.1867811438681572,1.9256117441147356,0.9053105719493667,0.10689023937979268,3.2366995159470866,-0.5687820738676072,0.9053105719493667,0.7679055479970575,2.836165185919543,-0.09905875539476565,-0.3116003386120246,-0.29362137810344713,0.30681128083133596 | 3,219 |
Motor neuron atrophy | 12 | 22 | 2.619587 | 0.008804 | P35637,Q99720,P22626,P07737,Q92804,P43243,Q15165,Q13510,P31483,P09651,Q16637,Q92734 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 96,130,191,385,136,670,154,419,431,586,403,677 | 2379,385,586,1840,191,431,96,670,876,1728,1140,419,1189,154,403,879,677,136,130,2953,1907,717 | -0.5127816595838254,0.9655856472779832,0.6121961750555308,-0.23998215837100623,1.6134312131752497,0.8901666692591385,2.3671810512426905,0.517155278900476,0.32321507233725794,-0.1867811438681572,0.14061496438072402,0.9053105719493667,0.10689023937979268,1.845285994530105,0.9355078676043538,0.32321507233725794,0.517155278900476,1.9654918389860268,2.0183777919842116,-0.9758785445560134,-0.2578126878849311,0.4851953858805861 | 3,219 |
Progressive cerebellar ataxia | 9 | 36 | 2.618811 | 0.008824 | P35637,Q8NI60,O75306,O76024,Q03426,Q9Y487,Q9Y619,Q9NW15,Q96CU9 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 96,289,190,264,141,18,243,315,116 | 2653,570,799,190,1459,264,1798,1155,1319,2111,1804,3174,2157,1212,2385,96,1037,2160,2635,1728,141,1140,1412,2529,335,924,289,116,928,810,1424,315,1792,1312,18,243 | -0.6823259973888944,0.627916326361481,0.3884511119152299,1.6134312131752497,-0.06429240403855782,1.3033130248343696,-0.22220031488448316,0.12377336021763811,0.02184122951698084,-0.3840232035503077,-0.22220031488448316,-2.083758514401128,-0.4022577865800413,0.08996530109043266,-0.5127816595838254,2.3671810512426905,0.2075721060916025,-0.4022577865800413,-0.663255694292154,-0.1867811438681572,1.9256117441147356,0.14061496438072402,-0.0297061989992813,-0.5875614889822378,1.1142289703794899,0.2903690579322796,1.2311257458045275,2.175119142227216,0.2903690579322796,0.3884511119152299,-0.0297061989992813,1.1582704354775262,-0.20446677062676033,0.038936518919033984,3.687756694083232,1.3605937226731146 | 3,219 |
Paraparesis | 11 | 30 | 2.609014 | 0.00908 | Q5XKP0,P35637,Q6DKK2,Q8N0X7,Q9Y5Y5,P04062,Q13510,Q9H6K4,Q9Y619,Q15813,Q9C0D9 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 445,96,163,295,197,105,419,14,243,376,480 | 1152,2455,2894,2895,105,1917,1212,1884,96,805,1728,1654,2785,1951,1818,543,1140,419,376,445,163,295,2362,480,14,1424,754,999,197,243 | 0.12377336021763811,-0.5500592938652186,-0.9159960560023168,-0.9159960560023168,2.290856236991885,-0.2756922953883126,0.08996530109043266,-0.2578126878849311,2.3671810512426905,0.3884511119152299,-0.1867811438681572,-0.15155214072249368,-0.7785852884708848,-0.29362137810344713,-0.22220031488448316,0.6748753590501604,0.14061496438072402,0.9053105719493667,0.9955452840839076,0.859787466513618,1.7777592561307913,1.2166087034830142,-0.49422583330773395,0.7986583902396478,3.8734982338727697,-0.0297061989992813,0.4369871407324282,0.240809140160788,1.5995887263604394,1.3605937226731146 | 3,219 |
Endopeptidase activity | 20 | 63 | 2.605887 | 0.009164 | P28070,Q6P179,Q9BXS4,P60900,P28072,P49721,Q4J6C6,Q99436,Q16740,Q9NZ08,Q2T9J0,P28074,Q96K76,O75844,P20618,O43847,O43292,P22695,P42892,P04632 | Functions | GO Molecular function | msigdb_gomf | 260,262,266,147,151,28,294,425,40,46,440,317,319,200,75,82,340,223,102,368 | 570,340,775,82,1260,200,368,2881,1463,1466,802,75,223,1568,260,151,317,2633,2872,3212,1887,691,102,1135,962,1289,28,1378,3186,1612,2784,147,3080,456,542,3099,1190,1895,40,440,294,577,1270,262,881,3128,3142,1196,1094,950,2440,1070,319,2097,425,651,968,266,1277,1278,46,889,999 | 0.627916326361481,1.084728683067828,0.4046666118339641,2.480459571042451,0.05598875083654143,1.571833533959058,1.010481220891836,-0.8961701064156942,-0.06429240403855782,-0.06429240403855782,0.3884511119152299,2.592334336196873,1.4316224032315916,-0.11651034953388262,1.3176718798343572,1.8587266321059235,1.143617604242851,-0.663255694292154,-0.8764104949654021,-3.750414824103546,-0.2578126878849311,0.5011930708427338,2.329100568036832,0.14061496438072402,0.257368256721385,0.038936518919033984,3.2597485190360773,-0.0124798039226905,-2.31145284936535,-0.13400802540056259,-0.7785852884708848,1.8855439980503246,-1.306235657380079,0.8445518061819609,0.6748753590501604,-1.3704042682529525,0.10689023937979268,-0.2578126878849311,2.931937430662331,0.874992360533424,1.2166087034830142,0.627916326361481,0.05598875083654143,1.3176718798343572,0.32321507233725794,-1.5010551895947977,-1.6349800480459569,0.10689023937979268,0.17417480799747104,0.27388813909007026,-0.5313926522763559,0.19089363138798773,1.143617604242851,-0.3658405952562187,0.9053105719493667,0.548974178419281,0.257368256721385,1.3033130248343696,0.05598875083654143,0.05598875083654143,2.836165185919543,0.32321507233725794,0.240809140160788 | 3,219 |
Increased bone mineral density | 7 | 25 | 2.600634 | 0.009305 | P04062,Q14108,Q13126,Q15813,Q14739,Q15392,P54802 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 105,142,51,376,56,61,250 | 2300,1105,2268,105,1566,2152,1838,2155,743,2838,380,250,1728,2314,1816,51,142,56,1191,515,61,376,2000,1970,910 | -0.4757246978649692,0.15741534907558857,-0.4572777844322593,2.290856236991885,-0.11651034953388262,-0.4022577865800413,-0.23998215837100623,-0.4022577865800413,0.4369871407324282,-0.837087716438348,0.9805801487420218,1.3320048573799028,-0.1867811438681572,-0.4757246978649692,-0.22220031488448316,2.7758065088467867,1.9256117441147356,2.739402554629938,0.10689023937979268,0.7060156085430525,2.6906403531600036,0.9955452840839076,-0.3116003386120246,-0.29362137810344713,0.30681128083133596 | 3,219 |
Abnormal mitochondria in muscle tissue | 6 | 22 | 2.599449 | 0.009337 | O75306,O43676,Q9Y6M9,Q86Y39,Q96CU9,P03886 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 190,7,238,311,116,57 | 7,799,190,2377,1459,1759,1156,57,1804,3174,1212,2635,311,924,1666,116,1516,378,1309,1255,999,238 | 4.151275569658641,0.3884511119152299,1.6134312131752497,-0.5127816595838254,-0.06429240403855782,-0.20446677062676033,0.12377336021763811,2.7272360837614658,-0.22220031488448316,-2.083758514401128,0.08996530109043266,-0.663255694292154,1.1582704354775262,0.2903690579322796,-0.15155214072249368,2.175119142227216,-0.0816528898016005,0.9955452840839076,0.038936518919033984,0.07299824094238225,0.240809140160788,1.3748498787678702 | 3,219 |
Steroid biosynthesis | 7 | 23 | 2.597521 | 0.00939 | Q16850,Q03426,Q15392,P54646,Q14739,Q9H3P7,Q15800 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 76,141,61,278,56,254,29 | 894,1564,2474,1836,1325,642,278,2998,141,2576,56,515,2464,61,2804,29,76,1171,1664,1517,254,391,1936 | 0.30681128083133596,-0.11651034953388262,-0.5687820738676072,-0.23998215837100623,0.02184122951698084,0.548974178419281,1.2600798177392025,-1.0770728414740884,1.9256117441147356,-0.6252922481428479,2.739402554629938,0.7060156085430525,-0.5500592938652186,2.6906403531600036,-0.7980226823314418,3.2366995159470866,2.579971557206447,0.12377336021763811,-0.15155214072249368,-0.0816528898016005,1.3320048573799028,0.9655856472779832,-0.2756922953883126 | 3,219 |
Ion transmembrane transport | 36 | 158 | 2.596902 | 0.009407 | Q9H4I9,P62942,P21796,P12235,P08183,Q9HC07,Q9Y6M7,Q8TB61,P53985,P45880,O75964,Q06787,Q9NW15,O00400,Q9H2D1,Q8N4V1,O43772,Q70HW3,O75844,Q7KZN9,P00846,Q9UDW1,Q9Y696,P98194,Q9C0H2,Q9UHG3,Q9UBX3,Q96NB2,P30825,Q9BQT8,P78417,Q9Y619,Q13423,P56134,Q9HD20,P51798 | Processes and pathways | GO Biological process | msigdb_gobp | 390,387,6,393,273,407,417,158,159,33,37,434,315,54,188,318,68,74,200,335,213,256,222,374,226,98,229,362,231,253,236,243,119,372,122,380 | 2453,54,2653,687,2906,1002,68,2625,932,2039,2185,2264,2758,799,1183,1260,1130,200,1600,1530,37,1131,2691,2457,1156,213,1078,2149,936,1286,2657,1601,2870,2881,1158,2961,273,1005,1915,1461,2962,1683,1159,393,1209,465,1107,2760,1007,1881,1976,3049,1838,6,1008,2599,1400,2600,1161,2662,572,231,1081,1186,2478,1982,1809,1843,1037,2160,33,1436,2987,2236,1110,380,1266,159,2164,1380,372,918,1845,2519,2604,387,236,374,984,555,2858,434,1353,2988,596,119,661,1014,3173,612,822,2525,1245,676,733,1703,74,335,746,600,318,724,3192,158,1177,2495,825,1932,726,2067,362,3018,2098,1421,253,928,790,226,2727,1905,188,770,1147,390,1710,1050,407,1120,122,582,793,315,816,229,256,437,98,1827,817,1339,2543,1396,931,1283,999,243,222,417 | -0.5500592938652186,2.7515530751583857,-0.6823259973888944,0.5011930708427338,-0.9358889993899692,0.2242105156109122,2.653898835377378,-0.663255694292154,0.27388813909007026,-0.3477095307450096,-0.42054478130569956,-0.4572777844322593,-0.7592105127205729,0.3884511119152299,0.10689023937979268,0.05598875083654143,0.14061496438072402,1.571833533959058,-0.13400802540056259,-0.09905875539476565,2.9794613003008097,0.14061496438072402,-0.7014560751754394,-0.5500592938652186,0.12377336021763811,1.5020304740736174,0.17417480799747104,-0.4022577865800413,0.27388813909007026,0.038936518919033984,-0.6823259973888944,-0.13400802540056259,-0.8764104949654021,-0.8961701064156942,0.12377336021763811,-0.9959765127527764,1.2745171327387752,0.2242105156109122,-0.2756922953883126,-0.06429240403855782,-0.9959765127527764,-0.16914305785560818,0.12377336021763811,0.950561610502623,0.08996530109043266,0.8139874535706313,0.15741534907558857,-0.7592105127205729,0.2242105156109122,-0.2578126878849311,-0.3116003386120246,-1.200912870498824,-0.23998215837100623,4.19336581363514,0.2242105156109122,-0.6442446228460273,-0.0297061989992813,-0.6442446228460273,0.12377336021763811,-0.6823259973888944,0.627916326361481,1.3890806941306666,0.17417480799747104,0.10689023937979268,-0.5687820738676072,-0.3116003386120246,-0.22220031488448316,-0.23998215837100623,0.2075721060916025,-0.4022577865800413,3.1788366810455857,-0.046976953777104945,-1.0566916417769305,-0.43888463081271056,0.15741534907558857,0.9805801487420218,0.05598875083654143,1.7913080821408316,-0.4022577865800413,-0.0124798039226905,0.9955452840839076,0.2903690579322796,-0.23998215837100623,-0.5875614889822378,-0.6442446228460273,0.9655856472779832,1.3748498787678702,0.9955452840839076,0.240809140160788,0.6592557088759661,-0.856716576558732,0.8901666692591385,0.004702563072839793,-1.0566916417769305,0.5964421007549159,2.1361981793017475,0.5330822391938458,0.2242105156109122,-2.059096766572429,0.5806538884509506,0.37219845949424474,-0.5875614889822378,0.07299824094238225,0.517155278900476,0.45309265624254375,-0.16914305785560818,2.6046804013362,1.1142289703794899,0.4369871407324282,0.5964421007549159,1.143617604242851,0.46916199239345446,-2.4688746459004234,1.8183403125254671,0.12377336021763811,-0.5687820738676072,0.37219845949424474,-0.2756922953883126,0.46916199239345446,-0.3477095307450096,1.0253881251741155,-1.1180539551826354,-0.3658405952562187,-0.0297061989992813,1.3320048573799028,0.2903690579322796,0.4046666118339641,1.417466826740965,-0.7206464789962234,-0.2578126878849311,1.6272504471321572,0.4208452065718874,0.14061496438072402,0.9655856472779832,-0.16914305785560818,0.2075721060916025,0.9355078676043538,0.15741534907558857,2.084031409919309,0.627916326361481,0.4046666118339641,1.1582704354775262,0.3884511119152299,1.4032863000627067,1.3320048573799028,0.8901666692591385,2.3671810512426905,-0.22220031488448316,0.3884511119152299,0.02184122951698084,-0.5875614889822378,-0.0124798039226905,0.2903690579322796,0.05598875083654143,0.240809140160788,1.3605937226731146,1.4457531575031033,0.9204242461273519 | 3,219 |
Glycerophospholipid biosynthesis | 17 | 38 | 2.584852 | 0.009742 | O94830,Q9NQZ5,Q9BVG9,Q8IV08,Q9NPH0,Q6P1A2,Q8WUK0,O15228,Q8NCC3,Q96N66,P40939,Q8NF37,Q8NAN2,Q8N2A8,Q9HBU6,O95674,Q9C0D9 | Processes and pathways | Reactome Pathways | msigdb_reactome | 410,458,166,234,268,204,589,550,83,212,432,601,637,88,58,219,480 | 624,913,550,1527,410,219,977,1947,1886,432,760,2838,1437,2945,919,2245,204,2247,234,88,637,83,601,589,2171,2586,212,968,2846,166,1903,480,58,1022,268,458,714,867 | 0.564831320865879,0.2903690579322796,0.6592557088759661,-0.09905875539476565,0.9204242461273519,1.4457531575031033,0.240809140160788,-0.29362137810344713,-0.2578126878849311,0.8901666692591385,0.4208452065718874,-0.837087716438348,-0.046976953777104945,-0.9758785445560134,0.2903690579322796,-0.43888463081271056,1.5579205959049545,-0.43888463081271056,1.3890806941306666,2.4302899290735995,0.564831320865879,2.480459571042451,0.5964421007549159,0.6121961750555308,-0.4022577865800413,-0.6252922481428479,1.5160389992590655,0.257368256721385,-0.837087716438348,1.7505956650985413,-0.2578126878849311,0.7986583902396478,2.7272360837614658,0.2242105156109122,1.2889281552491543,0.8445518061819609,0.4851953858805861,0.3395806940145738 | 3,219 |
Leukodystrophy | 12 | 59 | 2.57367 | 0.010063 | O75306,Q9Y5Y5,O43676,Q53FT3,Q9Y6M9,Q7KZN9,P07602,Q86Y39,Q9NPL8,Q96CU9,Q15067,P03886 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 190,197,7,12,238,335,112,311,378,116,216,57 | 2653,1562,756,7,1944,1525,799,190,2377,1459,2455,1155,1759,57,897,112,1799,1319,2778,3183,1804,1323,1917,3174,2157,1212,2272,2635,1571,1654,1012,1818,2201,2355,216,1412,1268,12,381,2529,335,2826,311,924,1666,2211,926,2022,116,928,1516,378,1309,795,1255,1792,754,197,238 | -0.6823259973888944,-0.11651034953388262,0.4208452065718874,4.151275569658641,-0.29362137810344713,-0.09905875539476565,0.3884511119152299,1.6134312131752497,-0.5127816595838254,-0.06429240403855782,-0.5500592938652186,0.12377336021763811,-0.20446677062676033,2.7272360837614658,0.30681128083133596,2.2138676701946065,-0.22220031488448316,0.02184122951698084,-0.7785852884708848,-2.2599685470928406,-0.22220031488448316,0.02184122951698084,-0.2756922953883126,-2.083758514401128,-0.4022577865800413,0.08996530109043266,-0.4572777844322593,-0.663255694292154,-0.11651034953388262,-0.15155214072249368,0.2242105156109122,-0.22220031488448316,-0.42054478130569956,-0.49422583330773395,1.4598592164393882,-0.0297061989992813,0.05598875083654143,3.905930249962819,0.9805801487420218,-0.5875614889822378,1.1142289703794899,-0.8175232899524535,1.1582704354775262,0.2903690579322796,-0.15155214072249368,-0.42054478130569956,0.2903690579322796,-0.3296295849566747,2.175119142227216,0.2903690579322796,-0.0816528898016005,0.9955452840839076,0.038936518919033984,0.4046666118339641,0.07299824094238225,-0.20446677062676033,0.4369871407324282,1.5995887263604394,1.3748498787678702 | 3,219 |
Abnormal muscle fiber morphology | 20 | 72 | 2.573444 | 0.010069 | Q99720,O43676,O95831,P12235,Q8NI60,P13807,P31483,P03886,Q9H2D1,P22626,Q70HW3,P07196,P00846,P51114,P61978,O75340,P35637,P50402,O14979,P23786 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 130,7,392,393,289,298,431,57,188,191,74,331,213,346,477,351,96,354,118,126 | 2653,118,7,2336,1599,351,1649,392,873,1156,213,2268,57,2959,936,1879,331,2598,586,2042,393,298,1840,191,126,1212,431,1186,96,2479,670,657,354,2236,346,1266,1471,1728,477,1817,1114,1014,2430,2803,1414,2888,2706,74,500,2644,1508,289,2211,2467,2586,1707,2614,130,1421,1370,1995,810,1905,188,2983,2974,3136,1934,2813,2566,999,972 | -0.6823259973888944,2.1361981793017475,4.151275569658641,-0.49422583330773395,-0.13400802540056259,1.0551154924195283,-0.15155214072249368,0.950561610502623,0.32321507233725794,0.12377336021763811,1.5020304740736174,-0.4572777844322593,2.7272360837614658,-0.9959765127527764,0.27388813909007026,-0.2578126878849311,1.1142289703794899,-0.6442446228460273,0.6121961750555308,-0.3477095307450096,0.950561610502623,1.2020647978678858,-0.23998215837100623,1.6134312131752497,2.0446992086793294,0.08996530109043266,0.8901666692591385,0.10689023937979268,2.3671810512426905,-0.5687820738676072,0.517155278900476,0.5330822391938458,1.040266161379893,-0.43888463081271056,1.0699362796846454,0.05598875083654143,-0.06429240403855782,-0.1867811438681572,0.7986583902396478,-0.22220031488448316,0.15741534907558857,0.2242105156109122,-0.5313926522763559,-0.7980226823314418,-0.0297061989992813,-0.8961701064156942,-0.7014560751754394,2.6046804013362,0.7524813868036361,-0.663255694292154,-0.0816528898016005,1.2311257458045275,-0.42054478130569956,-0.5500592938652186,-0.6252922481428479,-0.16914305785560818,-0.6442446228460273,2.0183777919842116,-0.0297061989992813,0.004702563072839793,-0.3116003386120246,0.3884511119152299,-0.2578126878849311,1.6272504471321572,-1.0363823429612895,-1.0161442081118819,-1.567593340775535,-0.2756922953883126,-0.7980226823314418,-0.6063980432373821,0.240809140160788,0.257368256721385 | 3,219 |
Muscle stiffness | 7 | 22 | 2.557955 | 0.010529 | P07602,P46020,Q9NW15,P00846,Q15392,P23786,P53985 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 112,433,315,213,61,126,159 | 2455,1206,213,1879,112,439,126,1884,433,1984,821,159,1654,964,61,2529,1625,841,2029,315,795,754 | -0.5500592938652186,0.08996530109043266,1.5020304740736174,-0.2578126878849311,2.2138676701946065,0.874992360533424,2.0446992086793294,-0.2578126878849311,0.8901666692591385,-0.3116003386120246,0.37219845949424474,1.7913080821408316,-0.15155214072249368,0.257368256721385,2.6906403531600036,-0.5875614889822378,-0.13400802540056259,0.3559084044891777,-0.3296295849566747,1.1582704354775262,0.4046666118339641,0.4369871407324282 | 3,219 |
Steroid biosynthetic process | 12 | 47 | 2.554736 | 0.010627 | Q9UBM7,Q9H2C2,O14734,Q6P1A2,Q03426,Q16850,Q15392,P54646,Q14739,Q9H3P7,P30536,Q15800 | Processes and pathways | GO Biological process | msigdb_gobp | 391,326,328,204,141,76,61,278,56,254,92,29 | 328,1030,2415,894,1564,2041,2474,1078,1159,1836,937,915,832,1839,2341,875,92,1325,2873,642,2085,278,2998,141,419,2576,1617,56,515,2464,61,2608,2319,2804,29,76,1171,204,1664,1276,2845,1517,326,254,391,930,1936 | 1.1142289703794899,0.2075721060916025,-0.5313926522763559,0.30681128083133596,-0.11651034953388262,-0.3477095307450096,-0.5687820738676072,0.17417480799747104,0.12377336021763811,-0.23998215837100623,0.27388813909007026,0.2903690579322796,0.3559084044891777,-0.23998215837100623,-0.49422583330773395,0.32321507233725794,2.405099723026584,0.02184122951698084,-0.8764104949654021,0.548974178419281,-0.3658405952562187,1.2600798177392025,-1.0770728414740884,1.9256117441147356,0.9053105719493667,-0.6252922481428479,-0.13400802540056259,2.739402554629938,0.7060156085430525,-0.5500592938652186,2.6906403531600036,-0.6442446228460273,-0.4757246978649692,-0.7980226823314418,3.2366995159470866,2.579971557206447,0.12377336021763811,1.5579205959049545,-0.15155214072249368,0.05598875083654143,-0.837087716438348,-0.0816528898016005,1.1289371667707588,1.3320048573799028,0.9655856472779832,0.2903690579322796,-0.2756922953883126 | 3,219 |
Nausea and vomiting | 30 | 138 | 2.551837 | 0.010716 | Q9UBM7,P07737,O43676,Q92804,Q9Y584,Q03426,Q15165,Q96EY8,Q01844,Q9NZ08,Q86Y39,P03886,O75306,Q9NSD9,Q5HYI8,P00846,Q8IZA0,P11117,P22695,P35637,P42892,Q99643,Q9Y6M9,P07602,Q16836,Q9Y619,Q96CU9,Q9NPL8,Q13423,P23786 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 391,385,7,136,137,141,154,284,168,46,311,57,190,202,337,213,90,352,223,96,102,106,238,112,113,243,116,378,119,126 | 2372,1182,775,7,1105,799,190,2377,1459,1649,2147,2379,1759,1156,2337,213,57,2381,3164,1878,384,112,385,3021,3022,1801,586,352,3097,2228,2476,1804,1838,1917,2340,223,126,2553,1762,3174,1212,1884,2925,2477,743,1533,96,2634,1162,1058,2745,3050,2192,2911,432,102,670,1134,1569,1984,1164,2635,876,1109,2274,1471,1571,2927,2115,1728,3198,1572,477,2314,1012,168,555,141,1818,1140,119,1189,2724,2355,1191,1700,154,635,1735,113,3141,3035,879,337,2864,2707,500,311,2127,90,924,647,1666,603,136,1275,2022,116,284,3175,3018,106,1370,1516,884,2253,2809,843,1022,378,202,1790,1309,46,795,1255,391,2448,1393,717,2000,817,2410,910,137,243,1971,238 | -0.5127816595838254,0.10689023937979268,0.4046666118339641,4.151275569658641,0.15741534907558857,0.3884511119152299,1.6134312131752497,-0.5127816595838254,-0.06429240403855782,-0.15155214072249368,-0.4022577865800413,-0.5127816595838254,-0.20446677062676033,0.12377336021763811,-0.49422583330773395,1.5020304740736174,2.7272360837614658,-0.5127816595838254,-1.8898724029456426,-0.2578126878849311,0.9655856472779832,2.2138676701946065,0.9655856472779832,-1.1386554079722488,-1.1386554079722488,-0.22220031488448316,0.6121961750555308,1.0551154924195283,-1.3704042682529525,-0.43888463081271056,-0.5687820738676072,-0.22220031488448316,-0.23998215837100623,-0.2756922953883126,-0.49422583330773395,1.4316224032315916,2.0446992086793294,-0.6063980432373821,-0.20446677062676033,-2.083758514401128,0.08996530109043266,-0.2578126878849311,-0.9558496030589478,-0.5687820738676072,0.4369871407324282,-0.09905875539476565,2.3671810512426905,-0.663255694292154,0.12377336021763811,0.19089363138798773,-0.7398977686794529,-1.200912870498824,-0.42054478130569956,-0.9358889993899692,0.8901666692591385,2.329100568036832,0.517155278900476,0.14061496438072402,-0.11651034953388262,-0.3116003386120246,0.12377336021763811,-0.663255694292154,0.32321507233725794,0.15741534907558857,-0.4572777844322593,-0.06429240403855782,-0.11651034953388262,-0.9558496030589478,-0.3840232035503077,-0.1867811438681572,-2.6033985640845696,-0.11651034953388262,0.7986583902396478,-0.4757246978649692,0.2242105156109122,1.7369806906741143,0.6592557088759661,1.9256117441147356,-0.22220031488448316,0.14061496438072402,2.1361981793017475,0.10689023937979268,-0.7206464789962234,-0.49422583330773395,0.10689023937979268,-0.16914305785560818,1.845285994530105,0.564831320865879,-0.1867811438681572,2.2138676701946065,-1.6349800480459569,-1.159331839849001,0.32321507233725794,1.099492860982002,-0.856716576558732,-0.7014560751754394,0.7524813868036361,1.1582704354775262,-0.3840232035503077,2.417703668148951,0.2903690579322796,0.548974178419281,-0.15155214072249368,0.5964421007549159,1.9654918389860268,0.05598875083654143,-0.3296295849566747,2.175119142227216,1.2456160694471252,-2.083758514401128,-1.1180539551826354,2.2780713578916147,0.004702563072839793,-0.0816528898016005,0.32321507233725794,-0.43888463081271056,-0.7980226823314418,0.3559084044891777,0.2242105156109122,0.9955452840839076,1.571833533959058,-0.20446677062676033,0.038936518919033984,2.836165185919543,0.4046666118339641,0.07299824094238225,0.9655856472779832,-0.5313926522763559,-0.0124798039226905,0.4851953858805861,-0.3116003386120246,0.3884511119152299,-0.5127816595838254,0.30681128083133596,1.952219165715867,1.3605937226731146,-0.29362137810344713,1.3748498787678702 | 3,219 |
Protein targeting to mitochondrion | 18 | 48 | 2.544662 | 0.010938 | O60830,Q8N4H5,Q9NS69,Q5JRX3,O95429,Q10713,O95831,Q9Y584,Q15388,P55786,Q9Y5J6,O14925,Q99595,Q9Y5J9,O00165,O14737,P62072,P30536 | Processes and pathways | GO Biological process | msigdb_gobp | 32,648,67,577,628,456,392,137,420,138,173,111,48,585,244,26,187,92 | 244,26,111,775,975,32,1260,848,1719,628,2893,392,873,1835,2778,1947,92,2664,744,1350,138,187,1438,456,420,2947,1579,2245,577,2208,648,3199,48,651,907,1019,1278,2099,67,1792,2684,1491,2621,2182,828,137,173,585 | 1.3463120934073578,3.2942202098706117,2.2138676701946065,0.4046666118339641,0.240809140160788,3.1788366810455857,0.05598875083654143,0.3395806940145738,-0.1867811438681572,0.564831320865879,-0.9159960560023168,0.950561610502623,0.32321507233725794,-0.23998215837100623,-0.7785852884708848,-0.29362137810344713,2.405099723026584,-0.6823259973888944,0.4369871407324282,0.004702563072839793,1.938925832208026,1.6272504471321572,-0.046976953777104945,0.8445518061819609,0.9053105719493667,-0.9758785445560134,-0.11651034953388262,-0.43888463081271056,0.627916326361481,-0.42054478130569956,0.548974178419281,-2.6033985640845696,2.7999968682905996,0.548974178419281,0.30681128083133596,0.2242105156109122,0.05598875083654143,-0.3658405952562187,2.666162311535732,-0.20446677062676033,-0.6823259973888944,-0.06429240403855782,-0.6442446228460273,-0.4022577865800413,0.37219845949424474,1.952219165715867,1.7233434559929421,0.627916326361481 | 3,219 |
Ascites | 9 | 24 | 2.528789 | 0.011446 | O15118,Q01844,Q9NSD9,P04062,Q13510,Q14108,O60566,Q14739,Q13043 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 131,168,202,105,419,142,464,56,542 | 131,1054,464,1152,105,1462,540,849,3050,1010,1403,1329,2013,1352,2237,168,3034,542,419,142,56,838,202,972 | 1.9919755786666307,0.19089363138798773,0.8139874535706313,0.12377336021763811,2.290856236991885,-0.06429240403855782,0.6748753590501604,0.3395806940145738,-1.200912870498824,0.2242105156109122,-0.0297061989992813,0.02184122951698084,-0.3296295849566747,0.004702563072839793,-0.43888463081271056,1.7369806906741143,-1.159331839849001,0.6748753590501604,0.9053105719493667,1.9256117441147356,2.739402554629938,0.3559084044891777,1.571833533959058,0.257368256721385 | 3,219 |
Spastic paraparesis | 9 | 23 | 2.523946 | 0.011605 | Q5XKP0,Q6DKK2,Q8N0X7,Q9Y5Y5,P04062,Q9H6K4,Q9Y619,Q15813,Q9C0D9 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 445,163,295,197,105,14,243,376,480 | 1152,2455,2894,2895,105,1917,1212,1884,1654,1818,543,376,445,163,295,2362,480,14,1424,754,999,197,243 | 0.12377336021763811,-0.5500592938652186,-0.9159960560023168,-0.9159960560023168,2.290856236991885,-0.2756922953883126,0.08996530109043266,-0.2578126878849311,-0.15155214072249368,-0.22220031488448316,0.6748753590501604,0.9955452840839076,0.859787466513618,1.7777592561307913,1.2166087034830142,-0.49422583330773395,0.7986583902396478,3.8734982338727697,-0.0297061989992813,0.4369871407324282,0.240809140160788,1.5995887263604394,1.3605937226731146 | 3,219 |
Abnormality of blood circulation | 10 | 64 | 2.521407 | 0.011689 | Q9UHX1,P04062,O76024,O75844,Q99643,Q03426,Q9NZ08,Q9Y487,Q14739,P23786 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 1,105,264,200,106,141,46,18,56,126 | 1181,1376,893,200,1564,264,2268,105,936,3164,1878,2835,3021,1462,540,1917,3129,2340,849,126,1762,1212,1842,2925,2477,1809,1058,332,1843,690,2911,1134,1569,1164,1010,2236,2274,2194,1213,1572,1474,1817,555,141,56,2395,1735,764,2580,1661,1480,2584,2494,1275,106,2983,619,46,1393,909,1,817,2567,18 | 0.10689023937979268,-0.0124798039226905,0.30681128083133596,1.571833533959058,-0.11651034953388262,1.3033130248343696,-0.4572777844322593,2.290856236991885,0.27388813909007026,-1.8898724029456426,-0.2578126878849311,-0.837087716438348,-1.1386554079722488,-0.06429240403855782,0.6748753590501604,-0.2756922953883126,-1.5231422110485722,-0.49422583330773395,0.3395806940145738,2.0446992086793294,-0.20446677062676033,0.08996530109043266,-0.23998215837100623,-0.9558496030589478,-0.5687820738676072,-0.22220031488448316,0.19089363138798773,1.1142289703794899,-0.23998215837100623,0.5011930708427338,-0.9358889993899692,0.14061496438072402,-0.11651034953388262,0.12377336021763811,0.2242105156109122,-0.43888463081271056,-0.4572777844322593,-0.42054478130569956,0.08996530109043266,-0.11651034953388262,-0.06429240403855782,-0.22220031488448316,0.6592557088759661,1.9256117441147356,2.739402554629938,-0.5127816595838254,-0.1867811438681572,0.4208452065718874,-0.6252922481428479,-0.15155214072249368,-0.06429240403855782,-0.6252922481428479,-0.5687820738676072,0.05598875083654143,2.2780713578916147,-1.0363823429612895,0.5806538884509506,2.836165185919543,-0.0124798039226905,0.30681128083133596,5.876223836886106,0.3884511119152299,-0.6063980432373821,3.687756694083232 | 3,219 |
Oxidative phosphorylation | 18 | 68 | 2.514051 | 0.011935 | O95139,O75306,P56134,O75964,P14406,O43676,Q99643,Q9Y6M9,Q7KZN9,P00846,O75208,Q9BSK2,P13073,P03886,Q9UDW1,Q9H3K2,O14949,P22695 | Processes and pathways | GO Biological process | msigdb_gobp | 537,190,372,37,386,7,106,238,335,213,438,215,465,57,256,124,247,223 | 2653,687,871,247,2654,7,2736,438,799,190,1183,2377,1459,1530,37,537,1679,895,1945,1155,1759,1156,213,57,959,1601,1915,1801,1683,465,386,1433,2658,1605,1804,1881,223,1008,2599,3174,2662,1212,1081,1884,551,1982,1134,2987,2635,671,1728,372,918,1381,2748,1412,2561,335,861,3018,106,1746,215,1905,124,256,1339,238 | -0.6823259973888944,0.5011930708427338,0.32321507233725794,1.3320048573799028,-0.6823259973888944,4.151275569658641,-0.7398977686794529,0.874992360533424,0.3884511119152299,1.6134312131752497,0.10689023937979268,-0.5127816595838254,-0.06429240403855782,-0.09905875539476565,2.9794613003008097,0.6748753590501604,-0.16914305785560818,0.30681128083133596,-0.29362137810344713,0.12377336021763811,-0.20446677062676033,0.12377336021763811,1.5020304740736174,2.7272360837614658,0.257368256721385,-0.13400802540056259,-0.2756922953883126,-0.22220031488448316,-0.16914305785560818,0.8139874535706313,0.9655856472779832,-0.046976953777104945,-0.6823259973888944,-0.13400802540056259,-0.22220031488448316,-0.2578126878849311,1.4316224032315916,0.2242105156109122,-0.6442446228460273,-2.083758514401128,-0.6823259973888944,0.08996530109043266,0.17417480799747104,-0.2578126878849311,0.6592557088759661,-0.3116003386120246,0.14061496438072402,-1.0566916417769305,-0.663255694292154,0.517155278900476,-0.1867811438681572,0.9955452840839076,0.2903690579322796,-0.0124798039226905,-0.7398977686794529,-0.0297061989992813,-0.6063980432373821,1.1142289703794899,0.3395806940145738,-1.1180539551826354,2.2780713578916147,-0.1867811438681572,1.4739407058524918,-0.2578126878849311,2.0709405477253173,1.3320048573799028,0.02184122951698084,1.3748498787678702 | 3,219 |
Abnormality of the vasculature of the eye | 21 | 71 | 2.510358 | 0.012061 | P28070,P06280,Q03426,Q13510,Q02978,Q9NZ08,Q10567,Q9NW15,Q14739,P10619,P03886,O75306,Q86SQ9,Q15555,P06865,P38435,P00846,Q9C0D9,Q99643,P07602,P04066 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 260,384,141,419,555,46,435,315,56,185,57,190,446,457,330,332,213,480,106,112,508 | 890,1181,1943,2715,1105,2005,1429,190,2302,2378,213,1430,57,508,1184,2741,384,330,112,2692,3021,185,1603,2694,1802,705,1566,2152,1917,3129,2155,260,2942,1212,551,2477,743,1435,1058,332,2911,1569,2162,1326,1213,2314,555,141,435,419,3117,56,1191,457,1479,446,991,1585,1781,2584,2647,2065,1336,106,480,1452,315,46,795,2000,910 | 0.30681128083133596,0.10689023937979268,-0.29362137810344713,-0.7206464789962234,0.15741534907558857,-0.3296295849566747,-0.046976953777104945,1.6134312131752497,-0.4757246978649692,-0.5127816595838254,1.5020304740736174,-0.046976953777104945,2.7272360837614658,0.7215366140730911,0.10689023937979268,-0.7398977686794529,0.9655856472779832,1.1142289703794899,2.2138676701946065,-0.7014560751754394,-1.1386554079722488,1.6548196110759805,-0.13400802540056259,-0.7014560751754394,-0.22220031488448316,0.4851953858805861,-0.11651034953388262,-0.4022577865800413,-0.2756922953883126,-1.5231422110485722,-0.4022577865800413,1.3176718798343572,-0.9758785445560134,0.08996530109043266,0.6592557088759661,-0.5687820738676072,0.4369871407324282,-0.046976953777104945,0.19089363138798773,1.1142289703794899,-0.9358889993899692,-0.11651034953388262,-0.4022577865800413,0.02184122951698084,0.08996530109043266,-0.4757246978649692,0.6592557088759661,1.9256117441147356,0.8901666692591385,0.9053105719493667,-1.4571526976673133,2.739402554629938,0.10689023937979268,0.8445518061819609,-0.06429240403855782,0.859787466513618,0.240809140160788,-0.11651034953388262,-0.20446677062676033,-0.6252922481428479,-0.663255694292154,-0.3477095307450096,0.02184122951698084,2.2780713578916147,0.7986583902396478,-0.046976953777104945,1.1582704354775262,2.836165185919543,0.4046666118339641,-0.3116003386120246,0.30681128083133596 | 3,219 |
Cellular respiration | 17 | 110 | 2.508987 | 0.012108 | Q9NZ45,O75306,O75874,O75964,O43676,P36404,P04062,Q99643,Q9Y6M9,Q13423,P00846,P48735,P03886,Q9BSK2,Q9UDW1,Q9H3K2,P22695 | Processes and pathways | GO Biological process | msigdb_gobp | 99,190,69,37,7,198,105,106,238,119,213,23,57,215,256,124,223 | 2653,687,871,247,2654,7,1525,2005,2736,438,799,190,1183,2377,2759,1459,1130,69,1530,37,537,1679,895,1945,1155,1759,1156,213,57,105,2628,959,1601,3021,1319,1915,1801,2188,1683,1760,465,2476,386,1433,1466,2658,1605,1804,1881,979,1917,223,1008,2599,3174,2662,2080,1212,1081,1884,551,198,1982,1058,2745,2782,2911,1134,760,2987,23,2635,2162,778,671,1471,1728,372,918,1381,2575,1988,119,1356,1700,635,2748,1412,1016,2561,335,2211,2534,861,3018,106,2500,2587,1746,215,1905,124,1710,99,2590,256,817,1339,2544,238 | -0.6823259973888944,0.5011930708427338,0.32321507233725794,1.3320048573799028,-0.6823259973888944,4.151275569658641,-0.09905875539476565,-0.3296295849566747,-0.7398977686794529,0.874992360533424,0.3884511119152299,1.6134312131752497,0.10689023937979268,-0.5127816595838254,-0.7592105127205729,-0.06429240403855782,0.14061496438072402,2.6416189707121984,-0.09905875539476565,2.9794613003008097,0.6748753590501604,-0.16914305785560818,0.30681128083133596,-0.29362137810344713,0.12377336021763811,-0.20446677062676033,0.12377336021763811,1.5020304740736174,2.7272360837614658,2.290856236991885,-0.663255694292154,0.257368256721385,-0.13400802540056259,-1.1386554079722488,0.02184122951698084,-0.2756922953883126,-0.22220031488448316,-0.42054478130569956,-0.16914305785560818,-0.20446677062676033,0.8139874535706313,-0.5687820738676072,0.9655856472779832,-0.046976953777104945,-0.06429240403855782,-0.6823259973888944,-0.13400802540056259,-0.22220031488448316,-0.2578126878849311,0.240809140160788,-0.2756922953883126,1.4316224032315916,0.2242105156109122,-0.6442446228460273,-2.083758514401128,-0.6823259973888944,-0.3658405952562187,0.08996530109043266,0.17417480799747104,-0.2578126878849311,0.6592557088759661,1.5857228718739784,-0.3116003386120246,0.19089363138798773,-0.7398977686794529,-0.7785852884708848,-0.9358889993899692,0.14061496438072402,0.4208452065718874,-1.0566916417769305,3.3628016428383716,-0.663255694292154,-0.4022577865800413,0.4046666118339641,0.517155278900476,-0.06429240403855782,-0.1867811438681572,0.9955452840839076,0.2903690579322796,-0.0124798039226905,-0.6252922481428479,-0.3116003386120246,2.1361981793017475,0.004702563072839793,-0.16914305785560818,0.564831320865879,-0.7398977686794529,-0.0297061989992813,0.2242105156109122,-0.6063980432373821,1.1142289703794899,-0.42054478130569956,-0.5875614889822378,0.3395806940145738,-1.1180539551826354,2.2780713578916147,-0.5687820738676072,-0.6252922481428479,-0.1867811438681572,1.4739407058524918,-0.2578126878849311,2.0709405477253173,-0.16914305785560818,2.354505635583359,-0.6252922481428479,1.3320048573799028,0.3884511119152299,0.02184122951698084,-0.5875614889822378,1.3748498787678702 | 3,219 |
Protein targeting | 36 | 118 | 2.508596 | 0.012121 | Q9UHB9,Q8N4H5,O75381,Q9Y584,O95831,P55786,Q14108,Q5BJH7,O60725,O14737,O14964,O60830,Q15388,P46379,Q9Y5J6,P61009,Q9UHD1,Q99595,Q9Y5J9,P62072,Q9NS69,Q5JRX3,Q9Y5Y5,Q10713,P30536,Q13438,Q12955,Q9Y2T2,Q15629,P57105,P43307,O14925,P50542,O00165,Q99523,O95429 | Processes and pathways | GO Biological process | msigdb_gobp | 512,648,513,137,392,138,142,143,271,26,285,32,420,42,173,418,437,48,585,187,67,577,197,456,92,597,596,221,97,355,109,111,498,244,377,628 | 2568,244,2996,1237,2413,26,111,285,775,975,1944,1717,271,32,513,1260,2456,848,1719,628,2893,392,873,1835,1800,2778,2110,978,1947,938,1400,2795,2600,92,1980,834,1981,2664,2573,1083,109,42,980,744,498,2601,1350,138,779,355,2667,418,2555,2519,2312,187,2604,2276,2670,1438,456,596,597,142,1292,822,420,97,2947,709,1579,2245,143,577,2725,3191,1445,1822,2208,3015,902,648,3199,2439,1707,751,377,1420,48,651,907,1019,1278,2444,952,2099,67,2100,1792,2684,909,512,437,1491,1492,2102,2877,2104,221,2621,2182,1283,828,137,173,585,1493,197 | -0.6252922481428479,1.3463120934073578,-1.0770728414740884,0.07299824094238225,-0.5313926522763559,3.2942202098706117,2.2138676701946065,1.2311257458045275,0.4046666118339641,0.240809140160788,-0.29362137810344713,-0.1867811438681572,1.2745171327387752,3.1788366810455857,0.7060156085430525,0.05598875083654143,-0.5500592938652186,0.3395806940145738,-0.1867811438681572,0.564831320865879,-0.9159960560023168,0.950561610502623,0.32321507233725794,-0.23998215837100623,-0.22220031488448316,-0.7785852884708848,-0.3840232035503077,0.240809140160788,-0.29362137810344713,0.27388813909007026,-0.0297061989992813,-0.7980226823314418,-0.6442446228460273,2.405099723026584,-0.3116003386120246,0.3559084044891777,-0.3116003386120246,-0.6823259973888944,-0.6252922481428479,0.17417480799747104,2.239605321056987,2.896137022744003,0.240809140160788,0.4369871407324282,0.7524813868036361,-0.6442446228460273,0.004702563072839793,1.938925832208026,0.4046666118339641,1.040266161379893,-0.6823259973888944,0.9053105719493667,-0.6063980432373821,-0.5875614889822378,-0.4757246978649692,1.6272504471321572,-0.6442446228460273,-0.4572777844322593,-0.6823259973888944,-0.046976953777104945,0.8445518061819609,0.5964421007549159,0.5964421007549159,1.9256117441147356,0.038936518919033984,0.37219845949424474,0.9053105719493667,2.3671810512426905,-0.9758785445560134,0.4851953858805861,-0.11651034953388262,-0.43888463081271056,1.9256117441147356,0.627916326361481,-0.7206464789962234,-2.4423315536275503,-0.046976953777104945,-0.22220031488448316,-0.42054478130569956,-1.1180539551826354,0.30681128083133596,0.548974178419281,-2.6033985640845696,-0.5313926522763559,-0.16914305785560818,0.4369871407324282,0.9955452840839076,-0.0297061989992813,2.7999968682905996,0.548974178419281,0.30681128083133596,0.2242105156109122,0.05598875083654143,-0.5313926522763559,0.27388813909007026,-0.3658405952562187,2.666162311535732,-0.3658405952562187,-0.20446677062676033,-0.6823259973888944,0.30681128083133596,0.7215366140730911,0.8901666692591385,-0.06429240403855782,-0.06429240403855782,-0.3658405952562187,-0.8764104949654021,-0.3658405952562187,1.4457531575031033,-0.6442446228460273,-0.4022577865800413,0.05598875083654143,0.37219845949424474,1.952219165715867,1.7233434559929421,0.627916326361481,-0.06429240403855782,1.5995887263604394 | 3,219 |
protein modifying enzyme | 7 | 24 | 2.507259 | 0.012167 | O75718,Q86YN1,O60725,Q92791,Q9UMR5,P50897,P13674 | Functions | Panther Protein class | panther_protein_class | 259,300,271,338,84,22,307 | 818,1874,774,976,872,271,259,307,22,1690,2798,1817,1574,2577,1221,359,557,300,1480,338,1484,1099,84,2879 | 0.37219845949424474,-0.2578126878849311,0.4046666118339641,0.240809140160788,0.32321507233725794,1.2745171327387752,1.3176718798343572,1.1582704354775262,3.5768907333196704,-0.16914305785560818,-0.7980226823314418,-0.22220031488448316,-0.11651034953388262,-0.6252922481428479,0.08996530109043266,1.0253881251741155,0.6592557088759661,1.2020647978678858,-0.06429240403855782,1.099492860982002,-0.06429240403855782,0.17417480799747104,2.4679433280004157,-0.8764104949654021 | 3,219 |
Ceramide metabolic process | 10 | 20 | 2.497003 | 0.012525 | O15269,P06280,P04062,P27544,P06865,Q13510,Q99805,Q8NCC3,Q96G23,O95470 | Processes and pathways | GO Biological process | msigdb_gobp | 473,384,105,394,330,419,210,83,252,306 | 473,892,775,306,105,384,330,2692,705,2339,394,1324,419,2432,2245,83,252,210,582,1425 | 0.7986583902396478,0.30681128083133596,0.4046666118339641,1.1582704354775262,2.290856236991885,0.9655856472779832,1.1142289703794899,-0.7014560751754394,0.4851953858805861,-0.49422583330773395,0.950561610502623,0.02184122951698084,0.9053105719493667,-0.5313926522763559,-0.43888463081271056,2.480459571042451,1.3320048573799028,1.53002344770046,0.627916326361481,-0.0297061989992813 | 3,219 |
Mitochondrial complex iv assembly | 6 | 16 | 2.496174 | 0.012554 | Q8N8Q8,P14406,Q7KZN9,Q9Y241,Q9Y6N1,Q9P0S2 | Processes and pathways | WikiPathways | msigdb_wp | 447,386,335,181,246,87 | 2653,1525,1156,1079,1683,465,386,1605,1881,335,447,928,87,181,1340,246 | -0.6823259973888944,-0.09905875539476565,0.12377336021763811,0.17417480799747104,-0.16914305785560818,0.8139874535706313,0.9655856472779832,-0.13400802540056259,-0.2578126878849311,1.1142289703794899,0.859787466513618,0.2903690579322796,2.455409687353435,1.69600177785008,0.02184122951698084,1.3463120934073578 | 3,219 |
Regulation of autophagy | 20 | 99 | 2.489143 | 0.012805 | O15118,P21796,Q8IXJ6,Q9BXS4,P12235,Q93050,Q9Y487,P54646,P09601,Q9UBQ0,P10619,Q8NHS3,O75844,P30536,Q9NZ45,P19474,P04062,P07602,P04632,O00165 | Processes and pathways | GO Biological process | msigdb_gobp | 131,6,8,266,393,13,18,278,156,316,185,193,200,92,99,103,105,112,368,244 | 244,1204,1029,1151,131,473,892,2300,2107,775,1677,2454,2007,200,1565,2880,2893,105,2740,368,2381,3193,1286,1680,2881,112,961,2304,2187,156,185,1132,393,2760,103,1947,1976,3049,6,2043,394,92,1809,1843,690,1725,2160,1010,744,644,278,2390,1845,2798,2767,2799,2428,2462,1219,2802,807,1895,1504,3073,1821,1193,1741,8,1661,193,859,3142,2991,13,2095,3018,1420,266,1867,1278,2444,792,1021,1869,2683,1790,99,795,316,717,1827,2222,1374,845,2621,2182,18,2713,1235 | 1.3463120934073578,0.08996530109043266,0.2075721060916025,0.12377336021763811,1.9919755786666307,0.7986583902396478,0.30681128083133596,-0.4757246978649692,-0.3840232035503077,0.4046666118339641,-0.16914305785560818,-0.5500592938652186,-0.3296295849566747,1.571833533959058,-0.11651034953388262,-0.8961701064156942,-0.9159960560023168,2.290856236991885,-0.7398977686794529,1.010481220891836,-0.5127816595838254,-2.5492293041362384,0.038936518919033984,-0.16914305785560818,-0.8961701064156942,2.2138676701946065,0.257368256721385,-0.4757246978649692,-0.42054478130569956,1.8318239214365153,1.6548196110759805,0.14061496438072402,0.950561610502623,-0.7592105127205729,2.316370764790158,-0.29362137810344713,-0.3116003386120246,-1.200912870498824,4.19336581363514,-0.3477095307450096,0.950561610502623,2.405099723026584,-0.22220031488448316,-0.23998215837100623,0.5011930708427338,-0.1867811438681572,-0.4022577865800413,0.2242105156109122,0.4369871407324282,0.548974178419281,1.2600798177392025,-0.5127816595838254,-0.23998215837100623,-0.7980226823314418,-0.7592105127205729,-0.7980226823314418,-0.5313926522763559,-0.5500592938652186,0.08996530109043266,-0.7980226823314418,0.3884511119152299,-0.2578126878849311,-0.0816528898016005,-1.285011033296226,-0.22220031488448316,0.10689023937979268,-0.1867811438681572,4.130167490643299,-0.15155214072249368,1.6134312131752497,0.3395806940145738,-1.6349800480459569,-1.0566916417769305,3.905930249962819,-0.3658405952562187,-1.1180539551826354,-0.0297061989992813,1.3033130248343696,-0.23998215837100623,0.05598875083654143,-0.5313926522763559,0.4046666118339641,0.2242105156109122,-0.23998215837100623,-0.6823259973888944,-0.20446677062676033,2.354505635583359,0.4046666118339641,1.1582704354775262,0.4851953858805861,-0.22220031488448316,-0.42054478130569956,0.004702563072839793,0.3559084044891777,-0.6442446228460273,-0.4022577865800413,3.687756694083232,-0.7014560751754394,0.08996530109043266 | 3,219 |
Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins | 16 | 70 | 2.48224 | 0.013056 | Q8N8Q8,O75306,O75964,O43676,Q99643,Q9Y6M9,Q86Y39,Q9NPL8,P00846,Q9Y6N1,Q9P0S2,P56134,P03886,Q9UDW1,O14949,P22695 | Processes and pathways | Reactome Pathways | msigdb_reactome | 447,190,37,7,106,238,311,378,213,246,87,372,57,256,247,223 | 2653,687,871,247,2654,7,1525,2736,799,190,2377,1459,1076,1530,37,537,1679,895,1945,1155,1759,1156,213,57,1601,1915,1079,1683,465,2476,2658,1605,1804,1881,1917,223,1008,2599,3174,1212,1081,1982,2745,2818,2987,2635,671,372,918,1988,635,2748,1412,311,924,447,1666,106,1551,928,1516,619,378,1309,1255,1792,87,256,238,246 | -0.6823259973888944,0.5011930708427338,0.32321507233725794,1.3320048573799028,-0.6823259973888944,4.151275569658641,-0.09905875539476565,-0.7398977686794529,0.3884511119152299,1.6134312131752497,-0.5127816595838254,-0.06429240403855782,0.17417480799747104,-0.09905875539476565,2.9794613003008097,0.6748753590501604,-0.16914305785560818,0.30681128083133596,-0.29362137810344713,0.12377336021763811,-0.20446677062676033,0.12377336021763811,1.5020304740736174,2.7272360837614658,-0.13400802540056259,-0.2756922953883126,0.17417480799747104,-0.16914305785560818,0.8139874535706313,-0.5687820738676072,-0.6823259973888944,-0.13400802540056259,-0.22220031488448316,-0.2578126878849311,-0.2756922953883126,1.4316224032315916,0.2242105156109122,-0.6442446228460273,-2.083758514401128,0.08996530109043266,0.17417480799747104,-0.3116003386120246,-0.7398977686794529,-0.8175232899524535,-1.0566916417769305,-0.663255694292154,0.517155278900476,0.9955452840839076,0.2903690579322796,-0.3116003386120246,0.564831320865879,-0.7398977686794529,-0.0297061989992813,1.1582704354775262,0.2903690579322796,0.859787466513618,-0.15155214072249368,2.2780713578916147,-0.09905875539476565,0.2903690579322796,-0.0816528898016005,0.5806538884509506,0.9955452840839076,0.038936518919033984,0.07299824094238225,-0.20446677062676033,2.455409687353435,1.3320048573799028,1.3748498787678702,1.3463120934073578 | 3,219 |
Mitochondrial calcium ion transport | 6 | 18 | 2.481708 | 0.013075 | Q92667,Q9H4I9,P45880,Q10713,P21796,Q8IYU8 | Processes and pathways | Reactome Pathways | msigdb_reactome | 517,390,33,456,6,600 | 1260,1131,6,1609,33,456,600,724,1177,517,2097,2098,1421,1278,390,1339,1396,999 | 0.05598875083654143,0.14061496438072402,4.19336581363514,-0.13400802540056259,3.1788366810455857,0.8445518061819609,0.5964421007549159,0.46916199239345446,0.12377336021763811,0.7060156085430525,-0.3658405952562187,-0.3658405952562187,-0.0297061989992813,0.05598875083654143,0.9655856472779832,0.02184122951698084,-0.0124798039226905,0.240809140160788 | 3,219 |
Negative regulation of secretion | 6 | 17 | 2.479232 | 0.013167 | Q16850,Q06787,Q16836,P17858,P00813,P09601 | Processes and pathways | GO Biological process | msigdb_gobp | 76,434,113,430,341,156 | 2184,1647,341,1722,156,430,1434,432,2601,1113,434,2239,113,76,924,1582,1147 | -0.42054478130569956,-0.15155214072249368,1.084728683067828,-0.1867811438681572,1.8318239214365153,0.8901666692591385,-0.046976953777104945,0.8901666692591385,-0.6442446228460273,0.15741534907558857,0.8901666692591385,-0.43888463081271056,2.2138676701946065,2.579971557206447,0.2903690579322796,-0.11651034953388262,0.14061496438072402 | 3,219 |
Translocation | 9 | 51 | 2.469624 | 0.013526 | O60830,Q9NS69,Q15629,P57740,Q9Y584,Q9Y5J6,Q9BTX1,Q99595,O14925 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 32,67,97,70,137,173,178,48,111 | 2732,2568,111,3143,975,32,513,1239,2229,1534,2515,2159,2346,1164,673,70,2667,2519,2165,187,2013,836,97,1579,879,1505,1445,615,578,414,405,579,1778,839,1366,1300,751,1514,48,178,3000,1488,1669,1233,67,3166,1313,2180,137,173,585 | -0.7398977686794529,-0.6252922481428479,2.2138676701946065,-1.6576364016996559,0.240809140160788,3.1788366810455857,0.7060156085430525,0.07299824094238225,-0.43888463081271056,-0.09905875539476565,-0.5875614889822378,-0.4022577865800413,-0.49422583330773395,0.12377336021763811,0.517155278900476,2.6293226533158274,-0.6823259973888944,-0.5875614889822378,-0.4022577865800413,1.6272504471321572,-0.3296295849566747,0.3559084044891777,2.3671810512426905,-0.11651034953388262,0.32321507233725794,-0.0816528898016005,-0.046976953777104945,0.5806538884509506,0.627916326361481,0.9204242461273519,0.9355078676043538,0.627916326361481,-0.20446677062676033,0.3559084044891777,0.004702563072839793,0.038936518919033984,0.4369871407324282,-0.0816528898016005,2.7999968682905996,1.7096838542654915,-1.0770728414740884,-0.06429240403855782,-0.15155214072249368,0.08996530109043266,2.666162311535732,-1.9136943396683315,0.038936518919033984,-0.4022577865800413,1.952219165715867,1.7233434559929421,0.627916326361481 | 3,219 |
Amyotrophic lateral sclerosis | 9 | 16 | 2.468656 | 0.013562 | P35637,P22626,Q99720,P07737,Q92804,P43243,P09651,P31483,Q15165 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 96,191,130,385,136,670,586,431,154 | 2379,385,586,191,431,96,670,876,1728,1140,1189,154,879,136,130,717 | -0.5127816595838254,0.9655856472779832,0.6121961750555308,1.6134312131752497,0.8901666692591385,2.3671810512426905,0.517155278900476,0.32321507233725794,-0.1867811438681572,0.14061496438072402,0.10689023937979268,1.845285994530105,0.32321507233725794,1.9654918389860268,2.0183777919842116,0.4851953858805861 | 3,219 |
Transport of small molecules | 36 | 154 | 2.468384 | 0.013572 | Q9H4I9,O15118,P28070,P21796,P12235,Q93050,Q8WTV0,P08183,Q9Y487,P60900,P28072,Q9Y6M7,P09601,P49721,Q8TB61,P53985,P45880,Q99436,Q9NW15,Q9BUN8,O00400,P11166,P30519,P28074,Q8N4V1,P36404,Q9BU23,Q70HW3,P20618,Q9C0H2,Q9UBX3,P30825,P98194,P48556,Q9HD20,P51798 | Processes and pathways | Reactome Pathways | msigdb_reactome | 390,131,260,6,393,13,16,273,18,147,151,417,156,28,158,159,33,425,315,313,54,439,60,317,318,198,199,74,75,226,229,231,374,371,122,380 | 1523,3008,54,1676,3010,131,1645,2264,1260,2415,2303,2869,2041,2510,1131,1430,1078,2149,1286,1157,2777,273,1005,1320,156,1462,439,393,1209,1973,1107,2760,2382,1007,2696,75,1976,3049,979,6,2781,2632,1808,1568,1400,2978,260,151,317,875,60,572,231,1884,1609,1533,1885,524,2817,198,1809,3050,1843,1083,2081,33,371,1289,28,2602,1110,380,1379,159,2164,1380,1728,779,147,2425,1845,1329,505,2118,2787,2197,1815,374,2671,1951,2556,456,1574,2351,597,661,2486,1441,2863,1410,1245,1065,676,1548,3131,74,2806,600,318,2710,724,3192,158,16,1177,517,13,1145,2097,425,2327,2535,2098,651,1421,199,313,226,2727,1637,770,1278,1147,390,1710,122,3159,3217,315,716,229,1427,1936,1827,1339,1829,2686,2408,1396,18,999,2713,1971,417 | -0.09905875539476565,-1.1180539551826354,2.7515530751583857,-0.16914305785560818,-1.1180539551826354,1.9919755786666307,-0.15155214072249368,-0.4572777844322593,0.05598875083654143,-0.5313926522763559,-0.4757246978649692,-0.8764104949654021,-0.3477095307450096,-0.5875614889822378,0.14061496438072402,-0.046976953777104945,0.17417480799747104,-0.4022577865800413,0.038936518919033984,0.12377336021763811,-0.7785852884708848,1.2745171327387752,0.2242105156109122,0.02184122951698084,1.8318239214365153,-0.06429240403855782,0.874992360533424,0.950561610502623,0.08996530109043266,-0.3116003386120246,0.15741534907558857,-0.7592105127205729,-0.5127816595838254,0.2242105156109122,-0.7014560751754394,2.592334336196873,-0.3116003386120246,-1.200912870498824,0.240809140160788,4.19336581363514,-0.7785852884708848,-0.663255694292154,-0.22220031488448316,-0.11651034953388262,-0.0297061989992813,-1.0363823429612895,1.3176718798343572,1.8587266321059235,1.143617604242851,0.32321507233725794,2.7028550450163786,0.627916326361481,1.3890806941306666,-0.2578126878849311,-0.13400802540056259,-0.09905875539476565,-0.2578126878849311,0.6904619242239327,-0.8175232899524535,1.5857228718739784,-0.22220031488448316,-1.200912870498824,-0.23998215837100623,0.17417480799747104,-0.3658405952562187,3.1788366810455857,0.9955452840839076,0.038936518919033984,3.2597485190360773,-0.6442446228460273,0.15741534907558857,0.9805801487420218,-0.0124798039226905,1.7913080821408316,-0.4022577865800413,-0.0124798039226905,-0.1867811438681572,0.4046666118339641,1.8855439980503246,-0.5313926522763559,-0.23998215837100623,0.02184122951698084,0.7370251408289138,-0.3840232035503077,-0.7785852884708848,-0.42054478130569956,-0.22220031488448316,0.9955452840839076,-0.6823259973888944,-0.29362137810344713,-0.6063980432373821,0.8445518061819609,-0.11651034953388262,-0.49422583330773395,0.5964421007549159,0.5330822391938458,-0.5687820738676072,-0.046976953777104945,-0.856716576558732,-0.0297061989992813,0.07299824094238225,0.19089363138798773,0.517155278900476,-0.09905875539476565,-1.5231422110485722,2.6046804013362,-0.7980226823314418,0.5964421007549159,1.143617604242851,-0.7014560751754394,0.46916199239345446,-2.4688746459004234,1.8183403125254671,3.7646475146351115,0.12377336021763811,0.7060156085430525,3.905930249962819,0.14061496438072402,-0.3658405952562187,0.9053105719493667,-0.4757246978649692,-0.5875614889822378,-0.3658405952562187,0.548974178419281,-0.0297061989992813,1.5857228718739784,1.1582704354775262,1.417466826740965,-0.7206464789962234,-0.13400802540056259,0.4208452065718874,0.05598875083654143,0.14061496438072402,0.9655856472779832,-0.16914305785560818,2.084031409919309,-1.8425667734679056,-10.508976746897172,1.1582704354775262,0.4851953858805861,1.4032863000627067,-0.0297061989992813,-0.2756922953883126,-0.22220031488448316,0.02184122951698084,-0.22220031488448316,-0.6823259973888944,-0.5127816595838254,-0.0124798039226905,3.687756694083232,0.240809140160788,-0.7014560751754394,-0.29362137810344713,0.9204242461273519 | 3,219 |
Cis golgi network | 6 | 17 | 2.46155 | 0.013834 | Q9NPR9,P24390,O43731,O00461,Q8TBA6,Q96JB2 | Localization | GO Cellular component | msigdb_gocc | 34,35,80,174,149,218 | 174,2956,80,830,35,2855,981,374,1219,1541,1736,149,2991,1743,218,34,1674 | 1.7096838542654915,-0.9959765127527764,2.505440145625614,0.3559084044891777,3.1089411622598995,-0.856716576558732,0.240809140160788,0.9955452840839076,0.08996530109043266,-0.09905875539476565,-0.1867811438681572,1.8721459336914674,-1.0566916417769305,-0.1867811438681572,1.4598592164393882,3.120625683590032,-0.15155214072249368 | 3,219 |
Rigidity | 14 | 59 | 2.461246 | 0.013846 | Q9Y287,Q9H2C2,Q86SQ9,P12235,P35270,P04062,Q06787,Q9H6K4,P07602,Q7LG56,P00846,Q96CU9,Q6Y7W6,Q15392 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 161,326,446,393,9,105,434,14,112,500,213,116,310,61 | 798,775,1944,1152,2455,2108,1206,213,105,897,112,393,1802,1263,1805,1081,9,2515,1843,2160,1653,1164,2701,821,1654,2312,1951,2799,2428,434,2239,543,1189,61,880,310,500,446,1625,1226,2494,116,2999,1630,2095,2614,3018,1421,841,1636,326,14,2029,795,1938,161,2182,754,999 | 0.3884511119152299,0.4046666118339641,-0.29362137810344713,0.12377336021763811,-0.5500592938652186,-0.3840232035503077,0.08996530109043266,1.5020304740736174,2.290856236991885,0.30681128083133596,2.2138676701946065,0.950561610502623,-0.22220031488448316,0.05598875083654143,-0.22220031488448316,0.17417480799747104,3.991922687702279,-0.5875614889822378,-0.23998215837100623,-0.4022577865800413,-0.15155214072249368,0.12377336021763811,-0.7014560751754394,0.37219845949424474,-0.15155214072249368,-0.4757246978649692,-0.29362137810344713,-0.7980226823314418,-0.5313926522763559,0.8901666692591385,-0.43888463081271056,0.6748753590501604,0.10689023937979268,2.6906403531600036,0.32321507233725794,1.1582704354775262,0.7524813868036361,0.859787466513618,-0.13400802540056259,0.08996530109043266,-0.5687820738676072,2.175119142227216,-1.0770728414740884,-0.13400802540056259,-0.3658405952562187,-0.6442446228460273,-1.1180539551826354,-0.0297061989992813,0.3559084044891777,-0.13400802540056259,1.1289371667707588,3.8734982338727697,-0.3296295849566747,0.4046666118339641,-0.2756922953883126,1.7913080821408316,-0.4022577865800413,0.4369871407324282,0.240809140160788 | 3,219 |
Negative regulation of rna catabolic process | 11 | 32 | 2.459766 | 0.013903 | Q13151,O60506,Q14011,P35637,Q92804,Q14103,Q06787,Q16539,Q99729,Q08J23,P98175 | Processes and pathways | GO Biological process | msigdb_gobp | 288,189,192,96,136,232,434,302,241,336,343 | 2372,189,1429,1797,1033,609,758,96,2818,2388,455,343,1847,434,1244,336,1140,288,192,232,922,302,1821,698,136,241,568,2563,2728,1964,1968,1125 | -0.5127816595838254,1.6134312131752497,-0.046976953777104945,-0.22220031488448316,0.2075721060916025,0.5806538884509506,0.4208452065718874,2.3671810512426905,-0.8175232899524535,-0.5127816595838254,0.8445518061819609,1.084728683067828,-0.23998215837100623,0.8901666692591385,0.07299824094238225,1.099492860982002,0.14061496438072402,1.2311257458045275,1.6134312131752497,1.3890806941306666,0.2903690579322796,1.1728958117690913,-0.22220031488448316,0.5011930708427338,1.9654918389860268,1.3605937226731146,0.6436027674453496,-0.6063980432373821,-0.7206464789962234,-0.29362137810344713,-0.29362137810344713,0.15741534907558857 | 3,219 |
Decreased activity of mitochondrial complex i | 11 | 38 | 2.454207 | 0.01412 | O75306,Q9UBX3,O43676,Q9Y584,Q70HW3,Q9Y6M9,Q86Y39,Q9NPL8,Q96CU9,P03886,Q5T440 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 190,229,7,137,74,238,311,378,116,57,381 | 7,3091,799,190,2377,1459,1649,1759,57,1804,3174,1652,2635,671,3123,1471,2888,381,74,311,924,1666,926,116,1630,2442,382,1516,811,1905,619,378,1309,1255,229,2472,137,238 | 4.151275569658641,-1.348931336259688,0.3884511119152299,1.6134312131752497,-0.5127816595838254,-0.06429240403855782,-0.15155214072249368,-0.20446677062676033,2.7272360837614658,-0.22220031488448316,-2.083758514401128,-0.15155214072249368,-0.663255694292154,0.517155278900476,-1.479059046842797,-0.06429240403855782,-0.8961701064156942,0.9805801487420218,2.6046804013362,1.1582704354775262,0.2903690579322796,-0.15155214072249368,0.2903690579322796,2.175119142227216,-0.13400802540056259,-0.5313926522763559,0.9805801487420218,-0.0816528898016005,0.3884511119152299,-0.2578126878849311,0.5806538884509506,0.9955452840839076,0.038936518919033984,0.07299824094238225,1.4032863000627067,-0.5500592938652186,1.952219165715867,1.3748498787678702 | 3,219 |
Action tremor | 9 | 57 | 2.450174 | 0.014279 | P35637,Q9Y287,Q99720,O75306,Q14108,Q9H6K4,P07602,Q9NR77,P03886 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 96,161,130,190,142,14,112,49,57 | 2733,570,1562,1944,2264,190,1678,1152,1719,2379,213,57,739,897,112,1799,1566,2152,1805,1323,1839,2155,2385,96,1037,2979,2839,1571,2115,1012,434,142,469,577,636,1361,2864,880,2358,1194,2322,1707,3018,130,841,528,14,1826,49,315,795,1312,1938,161,2451,2182,999 | -0.7398977686794529,0.627916326361481,-0.11651034953388262,-0.29362137810344713,-0.4572777844322593,1.6134312131752497,-0.16914305785560818,0.12377336021763811,-0.1867811438681572,-0.5127816595838254,1.5020304740736174,2.7272360837614658,0.4369871407324282,0.30681128083133596,2.2138676701946065,-0.22220031488448316,-0.11651034953388262,-0.4022577865800413,-0.22220031488448316,0.02184122951698084,-0.23998215837100623,-0.4022577865800413,-0.5127816595838254,2.3671810512426905,0.2075721060916025,-1.0363823429612895,-0.837087716438348,-0.11651034953388262,-0.3840232035503077,0.2242105156109122,0.8901666692591385,1.9256117441147356,0.8139874535706313,0.627916326361481,0.564831320865879,0.004702563072839793,-0.856716576558732,0.32321507233725794,-0.49422583330773395,0.10689023937979268,-0.4757246978649692,-0.16914305785560818,-1.1180539551826354,2.0183777919842116,0.3559084044891777,0.6904619242239327,3.8734982338727697,-0.22220031488448316,2.7879095428710334,1.1582704354775262,0.4046666118339641,0.038936518919033984,-0.2756922953883126,1.7913080821408316,-0.5313926522763559,-0.4022577865800413,0.240809140160788 | 3,219 |
Predicted secreted proteins | 14 | 53 | 2.446316 | 0.014432 | Q9Y287,O75718,P14174,Q6P179,Q8WUJ1,P80303,P43490,Q9NZ08,Q08380,O60888,Q9HB40,Q9UMX5,Q02818,Q15165 | Functions | Protein Atlas Protein class | protein_atlas_protein_class | 161,259,3,262,133,41,10,46,179,52,21,150,282,154 | 912,976,52,259,935,329,1430,1722,936,2742,2870,2187,2042,3,1466,2420,2232,3212,10,2783,2194,1329,2704,41,3211,460,282,1731,179,1818,2722,154,2642,262,1742,1225,3016,1899,133,2361,748,2250,3083,426,593,1148,1906,3136,21,46,150,161,910 | 0.2903690579322796,0.240809140160788,2.7636877063561913,1.3176718798343572,0.27388813909007026,1.1142289703794899,-0.046976953777104945,-0.1867811438681572,0.27388813909007026,-0.7398977686794529,-0.8764104949654021,-0.42054478130569956,-0.3477095307450096,4.524257799898794,-0.06429240403855782,-0.5313926522763559,-0.43888463081271056,-3.750414824103546,3.9704911872306314,-0.7785852884708848,-0.42054478130569956,0.02184122951698084,-0.7014560751754394,2.908085603546299,-3.6875828771630283,0.8292851967373376,1.2456160694471252,-0.1867811438681572,1.69600177785008,-0.22220031488448316,-0.7206464789962234,1.845285994530105,-0.663255694292154,1.3176718798343572,-0.1867811438681572,0.08996530109043266,-1.1180539551826354,-0.2578126878849311,1.9919755786666307,-0.49422583330773395,0.4369871407324282,-0.43888463081271056,-1.306235657380079,0.9053105719493667,0.6121961750555308,0.14061496438072402,-0.2578126878849311,-1.567593340775535,3.6546244885008625,2.836165185919543,1.8721459336914674,1.7913080821408316,0.30681128083133596 | 3,219 |
Nucleophile aminohydrolases, N-terminal [IPR029055] | 7 | 17 | 2.440832 | 0.014653 | Q06203,P28070,P20618,P60900,P28072,P49721,P28074 | Sequence | InterPro Superfamily | interpro_homologous_superfamily | 63,260,75,147,151,28,317 | 3010,1431,75,2781,2632,1808,1568,2978,260,151,317,1289,28,147,63,1114,425 | -1.1180539551826354,-0.046976953777104945,2.592334336196873,-0.7785852884708848,-0.663255694292154,-0.22220031488448316,-0.11651034953388262,-1.0363823429612895,1.3176718798343572,1.8587266321059235,1.143617604242851,0.038936518919033984,3.2597485190360773,1.8855439980503246,2.666162311535732,0.15741534907558857,0.9053105719493667 | 3,219 |
Focal t2 hyperintense brainstem lesion | 6 | 19 | 2.438806 | 0.014736 | O75306,O43676,Q9Y6M9,Q86Y39,Q96CU9,P03886 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 190,7,238,311,116,57 | 7,799,190,2377,1459,1759,57,1804,3174,2635,311,924,1666,116,1516,378,1309,1255,238 | 4.151275569658641,0.3884511119152299,1.6134312131752497,-0.5127816595838254,-0.06429240403855782,-0.20446677062676033,2.7272360837614658,-0.22220031488448316,-2.083758514401128,-0.663255694292154,1.1582704354775262,0.2903690579322796,-0.15155214072249368,2.175119142227216,-0.0816528898016005,0.9955452840839076,0.038936518919033984,0.07299824094238225,1.3748498787678702 | 3,219 |
Aerobic respiration | 18 | 93 | 2.438377 | 0.014753 | O75306,O75874,O75964,O43676,P36404,Q99643,Q9Y6M9,Q7KZN9,Q13423,P00846,P48735,P56134,P03886,Q9BSK2,Q9UDW1,Q9H3K2,O14949,P22695 | Processes and pathways | GO Biological process | msigdb_gobp | 190,69,37,7,198,106,238,335,119,213,23,372,57,215,256,124,247,223 | 2653,687,871,247,2654,7,2005,2736,438,799,190,1183,2377,2759,1459,69,1530,37,537,1679,895,1945,1155,1759,1156,213,57,959,1601,3021,1319,1915,1801,2188,1683,1760,465,386,1433,1466,2658,1605,1804,1881,979,1917,223,1008,2599,3174,2662,2080,1212,1081,1884,551,198,1982,1058,2782,2911,1134,2987,23,2635,2162,778,671,1471,1728,372,918,1381,2575,119,1356,2748,1412,2561,335,2534,861,3018,106,2500,1746,215,1905,124,2590,256,1339,238 | -0.6823259973888944,0.5011930708427338,0.32321507233725794,1.3320048573799028,-0.6823259973888944,4.151275569658641,-0.3296295849566747,-0.7398977686794529,0.874992360533424,0.3884511119152299,1.6134312131752497,0.10689023937979268,-0.5127816595838254,-0.7592105127205729,-0.06429240403855782,2.6416189707121984,-0.09905875539476565,2.9794613003008097,0.6748753590501604,-0.16914305785560818,0.30681128083133596,-0.29362137810344713,0.12377336021763811,-0.20446677062676033,0.12377336021763811,1.5020304740736174,2.7272360837614658,0.257368256721385,-0.13400802540056259,-1.1386554079722488,0.02184122951698084,-0.2756922953883126,-0.22220031488448316,-0.42054478130569956,-0.16914305785560818,-0.20446677062676033,0.8139874535706313,0.9655856472779832,-0.046976953777104945,-0.06429240403855782,-0.6823259973888944,-0.13400802540056259,-0.22220031488448316,-0.2578126878849311,0.240809140160788,-0.2756922953883126,1.4316224032315916,0.2242105156109122,-0.6442446228460273,-2.083758514401128,-0.6823259973888944,-0.3658405952562187,0.08996530109043266,0.17417480799747104,-0.2578126878849311,0.6592557088759661,1.5857228718739784,-0.3116003386120246,0.19089363138798773,-0.7785852884708848,-0.9358889993899692,0.14061496438072402,-1.0566916417769305,3.3628016428383716,-0.663255694292154,-0.4022577865800413,0.4046666118339641,0.517155278900476,-0.06429240403855782,-0.1867811438681572,0.9955452840839076,0.2903690579322796,-0.0124798039226905,-0.6252922481428479,2.1361981793017475,0.004702563072839793,-0.7398977686794529,-0.0297061989992813,-0.6063980432373821,1.1142289703794899,-0.5875614889822378,0.3395806940145738,-1.1180539551826354,2.2780713578916147,-0.5687820738676072,-0.1867811438681572,1.4739407058524918,-0.2578126878849311,2.0709405477253173,-0.6252922481428479,1.3320048573799028,0.02184122951698084,1.3748498787678702 | 3,219 |
Increased serum pyruvate | 10 | 36 | 2.432705 | 0.014987 | O75306,O43676,Q70HW3,Q9Y6M9,Q86Y39,Q9NPL8,Q96CU9,Q9P0S2,P03886,P22695 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 190,7,74,238,311,378,116,87,57,223 | 1376,7,799,190,2377,1459,392,1759,1206,57,1319,3183,1804,1917,223,3174,1887,2635,2701,2355,577,74,311,924,1666,116,2614,1516,951,1022,378,1309,1255,87,2813,238 | -0.0124798039226905,4.151275569658641,0.3884511119152299,1.6134312131752497,-0.5127816595838254,-0.06429240403855782,0.950561610502623,-0.20446677062676033,0.08996530109043266,2.7272360837614658,0.02184122951698084,-2.2599685470928406,-0.22220031488448316,-0.2756922953883126,1.4316224032315916,-2.083758514401128,-0.2578126878849311,-0.663255694292154,-0.7014560751754394,-0.49422583330773395,0.627916326361481,2.6046804013362,1.1582704354775262,0.2903690579322796,-0.15155214072249368,2.175119142227216,-0.6442446228460273,-0.0816528898016005,0.27388813909007026,0.2242105156109122,0.9955452840839076,0.038936518919033984,0.07299824094238225,2.455409687353435,-0.7980226823314418,1.3748498787678702 | 3,219 |
Lipid homeostasis | 7 | 30 | 2.429238 | 0.015131 | O15118,Q5BJF2,Q96CP7,O15254,Q8WTV0,P09455,Q15067 | Processes and pathways | GO Biological process | msigdb_gobp | 131,164,72,171,16,115,216 | 797,131,171,625,1564,1345,115,2270,2191,1884,1133,1533,278,1329,3179,216,164,2126,16,2586,72,2999,2176,2329,1022,1997,2298,1051,1971,829 | 0.3884511119152299,1.9919755786666307,1.7233434559929421,0.564831320865879,-0.11651034953388262,0.004702563072839793,2.175119142227216,-0.4572777844322593,-0.42054478130569956,-0.2578126878849311,0.14061496438072402,-0.09905875539476565,1.2600798177392025,0.02184122951698084,-2.158511158077036,1.4598592164393882,1.7641884852130048,-0.3840232035503077,3.7646475146351115,-0.6252922481428479,2.6170098185454913,-1.0770728414740884,-0.4022577865800413,-0.4757246978649692,0.2242105156109122,-0.3116003386120246,-0.4572777844322593,0.2075721060916025,-0.29362137810344713,0.37219845949424474 | 3,219 |
Phospholipid metabolism | 19 | 54 | 2.427197 | 0.015216 | Q9C0I1,Q9NPH0,O94830,Q9BVG9,O15228,P40939,Q9HBU6,Q10713,Q9NQZ5,Q6P1A2,Q8WUK0,Q8NCC3,Q96N66,Q8NF37,Q8N2A8,O95674,Q9C0D9,Q8IV08,Q8NAN2 | Processes and pathways | Reactome Pathways | msigdb_reactome | 520,268,410,166,550,432,58,456,458,204,589,83,212,601,88,219,480,234,637 | 1151,624,913,550,1527,410,219,977,1947,2306,741,1886,432,805,760,2838,1437,2945,2116,919,2278,456,1576,2245,204,2247,234,2358,88,1663,637,83,601,859,589,2171,2586,212,1745,1420,968,2846,1515,166,1903,480,520,58,1022,268,458,1254,714,867 | 0.12377336021763811,0.564831320865879,0.2903690579322796,0.6592557088759661,-0.09905875539476565,0.9204242461273519,1.4457531575031033,0.240809140160788,-0.29362137810344713,-0.4757246978649692,0.4369871407324282,-0.2578126878849311,0.8901666692591385,0.3884511119152299,0.4208452065718874,-0.837087716438348,-0.046976953777104945,-0.9758785445560134,-0.3840232035503077,0.2903690579322796,-0.4572777844322593,0.8445518061819609,-0.11651034953388262,-0.43888463081271056,1.5579205959049545,-0.43888463081271056,1.3890806941306666,-0.49422583330773395,2.4302899290735995,-0.15155214072249368,0.564831320865879,2.480459571042451,0.5964421007549159,0.3395806940145738,0.6121961750555308,-0.4022577865800413,-0.6252922481428479,1.5160389992590655,-0.1867811438681572,-0.0297061989992813,0.257368256721385,-0.837087716438348,-0.0816528898016005,1.7505956650985413,-0.2578126878849311,0.7986583902396478,0.7060156085430525,2.7272360837614658,0.2242105156109122,1.2889281552491543,0.8445518061819609,0.07299824094238225,0.4851953858805861,0.3395806940145738 | 3,219 |
Contractures of the joints of the upper limbs | 13 | 71 | 2.426878 | 0.015229 | P35637,Q99720,P57740,Q13509,P42892,Q7LGA3,O75844,P07196,Q9NR77,Q9Y619,Q8IZA0,Q15392,P23786 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 96,130,70,292,102,233,200,331,49,243,90,61,126 | 1151,1911,1562,1182,2300,535,2336,976,1129,1563,200,2041,757,2268,1879,331,915,1566,1838,1840,126,1763,1686,2342,96,1325,1009,102,1059,2838,354,498,2701,2115,1692,70,2278,1817,292,2463,1014,2724,2790,852,1504,61,1045,1388,2320,233,90,1778,1584,2467,725,2585,766,750,3144,2966,1514,130,1995,528,1337,618,2403,49,1027,2687,243 | 0.12377336021763811,-0.2756922953883126,-0.11651034953388262,0.10689023937979268,-0.4757246978649692,0.6748753590501604,-0.49422583330773395,0.240809140160788,0.14061496438072402,-0.11651034953388262,1.571833533959058,-0.3477095307450096,0.4208452065718874,-0.4572777844322593,-0.2578126878849311,1.1142289703794899,0.2903690579322796,-0.11651034953388262,-0.23998215837100623,-0.23998215837100623,2.0446992086793294,-0.20446677062676033,-0.16914305785560818,-0.49422583330773395,2.3671810512426905,0.02184122951698084,0.2242105156109122,2.329100568036832,0.19089363138798773,-0.837087716438348,1.040266161379893,0.7524813868036361,-0.7014560751754394,-0.3840232035503077,-0.16914305785560818,2.6293226533158274,-0.4572777844322593,-0.22220031488448316,1.2166087034830142,-0.5500592938652186,0.2242105156109122,-0.7206464789962234,-0.7785852884708848,0.3395806940145738,-0.0816528898016005,2.6906403531600036,0.2075721060916025,-0.0124798039226905,-0.4757246978649692,1.3890806941306666,2.417703668148951,-0.20446677062676033,-0.11651034953388262,-0.5500592938652186,0.46916199239345446,-0.6252922481428479,0.4208452065718874,0.4369871407324282,-1.6576364016996559,-0.9959765127527764,-0.0816528898016005,2.0183777919842116,-0.3116003386120246,0.6904619242239327,0.02184122951698084,0.5806538884509506,-0.5127816595838254,2.7879095428710334,0.2242105156109122,-0.6823259973888944,1.3605937226731146 | 3,219 |
Organic hydroxy compound metabolic process | 27 | 116 | 2.425312 | 0.015295 | Q9UBM7,O15118,Q9BY49,P35270,Q03426,Q8WTV0,P00374,Q14914,P48735,P54646,Q15800,Q13510,Q6NUM9,Q14739,Q15392,Q16822,Q9H2C2,Q86SQ9,O75874,Q10713,O14734,Q16850,Q6P1A2,P38435,O15269,P04062,Q9BQE5 | Processes and pathways | GO Biological process | msigdb_gobp | 391,131,389,9,141,16,145,20,23,278,29,419,303,56,61,65,326,446,69,456,328,76,204,332,473,105,125 | 3103,328,1030,131,473,892,2037,2005,2737,2415,1130,894,69,1564,2041,2380,1206,145,2474,2337,105,2381,936,1004,2078,2853,3012,1159,1106,1836,2882,937,915,2270,3129,832,1839,2341,875,1979,759,1133,9,1533,1325,332,3050,2873,760,642,23,1984,2162,778,2273,2701,475,2085,278,1770,3089,1891,1329,2671,2998,2278,141,456,419,3070,1576,2576,1617,56,20,2524,515,2464,61,2319,2804,29,65,76,303,204,446,1663,990,2492,16,2586,2999,2095,1276,3018,2845,2500,125,1303,389,326,2983,1965,1638,1869,582,727,391,2298,1936,1372,753,3077,3187,2594 | -1.391961876631989,1.1142289703794899,0.2075721060916025,1.9919755786666307,0.7986583902396478,0.30681128083133596,-0.3477095307450096,-0.3296295849566747,-0.7398977686794529,-0.5313926522763559,0.14061496438072402,0.30681128083133596,2.6416189707121984,-0.11651034953388262,-0.3477095307450096,-0.5127816595838254,0.08996530109043266,1.9122768063716753,-0.5687820738676072,-0.49422583330773395,2.290856236991885,-0.5127816595838254,0.27388813909007026,0.2242105156109122,-0.3658405952562187,-0.856716576558732,-1.1180539551826354,0.12377336021763811,0.15741534907558857,-0.23998215837100623,-0.8961701064156942,0.27388813909007026,0.2903690579322796,-0.4572777844322593,-1.5231422110485722,0.3559084044891777,-0.23998215837100623,-0.49422583330773395,0.32321507233725794,-0.3116003386120246,0.4208452065718874,0.14061496438072402,3.991922687702279,-0.09905875539476565,0.02184122951698084,1.1142289703794899,-1.200912870498824,-0.8764104949654021,0.4208452065718874,0.548974178419281,3.3628016428383716,-0.3116003386120246,-0.4022577865800413,0.4046666118339641,-0.4572777844322593,-0.7014560751754394,0.7986583902396478,-0.3658405952562187,1.2600798177392025,-0.20446677062676033,-1.3275421151096782,-0.2578126878849311,0.02184122951698084,-0.6823259973888944,-1.0770728414740884,-0.4572777844322593,1.9256117441147356,0.8445518061819609,0.9053105719493667,-1.285011033296226,-0.11651034953388262,-0.6252922481428479,-0.13400802540056259,2.739402554629938,3.6656806041326533,-0.5875614889822378,0.7060156085430525,-0.5500592938652186,2.6906403531600036,-0.4757246978649692,-0.7980226823314418,3.2366995159470866,2.666162311535732,2.579971557206447,1.1728958117690913,1.5579205959049545,0.859787466513618,-0.15155214072249368,0.240809140160788,-0.5687820738676072,3.7646475146351115,-0.6252922481428479,-1.0770728414740884,-0.3658405952562187,0.05598875083654143,-1.1180539551826354,-0.837087716438348,-0.5687820738676072,2.0578298433871516,0.038936518919033984,0.9655856472779832,1.1289371667707588,-1.0363823429612895,-0.29362137810344713,-0.13400802540056259,-0.23998215837100623,0.627916326361481,0.46916199239345446,0.9655856472779832,-0.4572777844322593,-0.2756922953883126,0.004702563072839793,0.4369871407324282,-1.285011033296226,-2.31145284936535,-0.6252922481428479 | 3,219 |
Transporter | 46 | 201 | 2.419986 | 0.015521 | P54105,Q9Y584,P12235,Q96H78,Q93050,O43752,P08183,Q9Y487,Q9HC07,Q9Y6M7,Q9P2W9,Q8NFH4,Q8TB61,P53985,O60499,P24390,Q15388,Q9Y5J6,Q10567,Q9UBQ0,O00400,Q9H2D1,O43772,P57740,Q9H2V7,Q70HW3,Q9HD45,O43731,Q99805,P00846,Q9BSK2,Q8N2H4,O14653,Q9UBX3,P56134,Q96NB2,P30825,Q96S59,Q15012,Q03518,Q9Y619,Q99523,P98194,Q8IXU6,Q9BQT8,Q9BQE5 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 135,137,393,11,13,270,273,18,407,417,416,414,158,159,286,35,420,173,435,316,54,188,68,70,73,74,78,80,210,213,215,348,350,229,372,362,231,363,110,240,243,377,374,120,253,125 | 2412,2184,2996,54,1316,1237,871,1238,2413,350,1030,3150,80,270,503,68,2625,286,2263,2957,933,1428,2414,2264,2007,1130,1530,777,1131,830,2379,1345,3002,2691,1055,873,213,1078,2149,1286,1601,273,1005,1320,439,1602,393,1209,978,453,1107,705,1007,1976,3049,35,1008,2599,875,1434,231,1884,573,1982,2515,1843,1037,2943,1437,981,498,1350,2926,692,1890,1266,2423,2194,1379,159,1213,135,2164,3013,1380,372,918,1535,70,1845,2519,2842,2702,2197,374,984,1951,3189,555,240,1772,1219,435,695,836,2484,878,3108,1851,2354,2167,1856,110,1356,2525,2902,420,1245,879,564,1295,745,1548,1703,74,1445,1991,120,615,348,3192,414,2248,158,579,1955,1046,2919,2991,1274,699,13,2647,1300,726,11,362,2095,363,377,1514,210,125,253,2793,841,215,1302,2727,1019,188,1637,770,73,2444,996,1710,1050,407,1120,78,3159,1101,1639,795,1791,1149,3168,416,2406,316,229,1827,686,2179,817,2955,737,1374,827,1674,584,18,137,173,2713,972,243,2850,829,417 | 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| 3,219 |
Intrinsic component of golgi membrane | 7 | 14 | 2.417192 | 0.015641 | Q9Y282,Q5BJH7,P98194,O43505,Q8N2H4,Q9NRB3,Q8TB61 | Localization | GO Cellular component | msigdb_gocc | 269,143,374,153,348,415,158 | 1150,2035,153,1833,374,2279,143,599,348,158,766,415,269,452 | 0.12377336021763811,-0.3477095307450096,1.845285994530105,-0.23998215837100623,0.9955452840839076,-0.4572777844322593,1.9256117441147356,0.5964421007549159,1.0699362796846454,1.8183403125254671,0.4208452065718874,0.9204242461273519,1.2889281552491543,0.859787466513618 | 3,219 |
Proton transporting two sector atpase complex | 6 | 24 | 2.408122 | 0.016035 | O75964,Q93050,Q8N511,Q9Y487,P00846,P56134 | Localization | GO Cellular component | msigdb_gocc | 37,13,81,18,213,372 | 1152,1530,37,213,1601,1976,3049,1008,2599,1982,1809,1843,2987,372,2765,918,1845,1065,81,13,399,1827,18,2713 | 0.12377336021763811,-0.09905875539476565,2.9794613003008097,1.5020304740736174,-0.13400802540056259,-0.3116003386120246,-1.200912870498824,0.2242105156109122,-0.6442446228460273,-0.3116003386120246,-0.22220031488448316,-0.23998215837100623,-1.0566916417769305,0.9955452840839076,-0.7592105127205729,0.2903690579322796,-0.23998215837100623,0.19089363138798773,2.505440145625614,3.905930249962819,0.950561610502623,-0.22220031488448316,3.687756694083232,-0.7014560751754394 | 3,219 |
Abnormality of temperature regulation | 21 | 99 | 2.407771 | 0.01605 | P14174,P28070,P06280,P35270,Q03426,Q9HC07,Q8NFH4,Q13510,Q9NZ08,Q9NR77,Q14739,P03886,Q5XKP0,O43772,P57740,P00846,P00813,P07602,P51798,Q5T440,P23786 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 3,260,384,9,141,407,414,419,46,49,56,57,445,68,70,213,341,112,380,381,126 | 1562,798,774,1002,68,2758,2455,2147,977,1206,1156,341,213,57,2959,2381,384,2835,112,3022,3012,1682,1462,1432,1159,3,1566,2152,1323,1840,126,2553,2156,260,9,1533,2634,1435,2572,2744,3050,690,2837,1569,1984,851,1164,1010,2236,1350,380,2636,1471,2389,1654,70,2555,477,1012,1816,141,836,542,1139,1384,419,661,2637,2724,56,2395,763,838,1222,3141,381,445,764,615,647,414,1778,1366,3118,1488,1019,1099,407,1120,2370,594,49,46,795,2072,1969,569,754,1675 | -0.11651034953388262,0.3884511119152299,0.4046666118339641,0.2242105156109122,2.653898835377378,-0.7592105127205729,-0.5500592938652186,-0.4022577865800413,0.240809140160788,0.08996530109043266,0.12377336021763811,1.084728683067828,1.5020304740736174,2.7272360837614658,-0.9959765127527764,-0.5127816595838254,0.9655856472779832,-0.837087716438348,2.2138676701946065,-1.1386554079722488,-1.1180539551826354,-0.16914305785560818,-0.06429240403855782,-0.046976953777104945,0.12377336021763811,4.524257799898794,-0.11651034953388262,-0.4022577865800413,0.02184122951698084,-0.23998215837100623,2.0446992086793294,-0.6063980432373821,-0.4022577865800413,1.3176718798343572,3.991922687702279,-0.09905875539476565,-0.663255694292154,-0.046976953777104945,-0.6252922481428479,-0.7398977686794529,-1.200912870498824,0.5011930708427338,-0.837087716438348,-0.11651034953388262,-0.3116003386120246,0.3395806940145738,0.12377336021763811,0.2242105156109122,-0.43888463081271056,0.004702563072839793,0.9805801487420218,-0.663255694292154,-0.06429240403855782,-0.5127816595838254,-0.15155214072249368,2.6293226533158274,-0.6063980432373821,0.7986583902396478,0.2242105156109122,-0.22220031488448316,1.9256117441147356,0.3559084044891777,0.6748753590501604,0.14061496438072402,-0.0124798039226905,0.9053105719493667,0.5330822391938458,-0.663255694292154,-0.7206464789962234,2.739402554629938,-0.5127816595838254,0.4208452065718874,0.3559084044891777,0.08996530109043266,-1.6349800480459569,0.9805801487420218,0.859787466513618,0.4208452065718874,0.5806538884509506,0.548974178419281,0.9204242461273519,-0.20446677062676033,0.004702563072839793,-1.4571526976673133,-0.06429240403855782,0.2242105156109122,0.17417480799747104,0.9355078676043538,0.15741534907558857,-0.49422583330773395,0.6121961750555308,2.7879095428710334,2.836165185919543,0.4046666118339641,-0.3477095307450096,-0.29362137810344713,0.6436027674453496,0.4369871407324282,-0.15155214072249368 | 3,219 |
Disproportionate short limb short stature | 12 | 23 | 2.400964 | 0.016352 | Q9UBM7,O75718,Q15125,Q7RTS9,Q32P28,Q7LGA3,Q14696,O15228,Q9BV10,Q03164,Q14739,Q15392 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 391,259,515,710,556,233,396,550,436,633,56,61 | 728,550,2186,259,1462,2420,1725,2943,633,396,56,515,61,556,1045,233,710,925,1584,2533,1368,436,391 | 0.45309265624254375,0.6592557088759661,-0.42054478130569956,1.3176718798343572,-0.06429240403855782,-0.5313926522763559,-0.1867811438681572,-0.9758785445560134,0.564831320865879,0.950561610502623,2.739402554629938,0.7060156085430525,2.6906403531600036,0.6592557088759661,0.2075721060916025,1.3890806941306666,0.4851953858805861,0.2903690579322796,-0.11651034953388262,-0.5875614889822378,0.004702563072839793,0.8901666692591385,0.9655856472779832 | 3,219 |
Paroxysmal involuntary eye movements | 7 | 21 | 2.397873 | 0.016491 | O75306,O43676,Q9Y6M9,Q86Y39,Q9NPL8,Q96CU9,P03886 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 190,7,238,311,378,116,57 | 7,799,190,2377,1459,1759,57,439,1804,3174,2635,311,924,1666,116,1516,378,1309,1255,2594,238 | 4.151275569658641,0.3884511119152299,1.6134312131752497,-0.5127816595838254,-0.06429240403855782,-0.20446677062676033,2.7272360837614658,0.874992360533424,-0.22220031488448316,-2.083758514401128,-0.663255694292154,1.1582704354775262,0.2903690579322796,-0.15155214072249368,2.175119142227216,-0.0816528898016005,0.9955452840839076,0.038936518919033984,0.07299824094238225,-0.6252922481428479,1.3748498787678702 | 3,219 |
Sphingolipid biosynthetic process | 8 | 18 | 2.397662 | 0.0165 | O15269,Q06136,P04062,P27544,Q13510,Q99805,Q96G23,O95470 | Processes and pathways | GO Biological process | msigdb_gobp | 473,132,105,394,419,210,252,306 | 473,892,306,105,2339,832,394,132,419,2432,2245,1506,252,210,582,1425,1024,1149 | 0.7986583902396478,0.30681128083133596,1.1582704354775262,2.290856236991885,-0.49422583330773395,0.3559084044891777,0.950561610502623,1.9919755786666307,0.9053105719493667,-0.5313926522763559,-0.43888463081271056,-0.0816528898016005,1.3320048573799028,1.53002344770046,0.627916326361481,-0.0297061989992813,0.2242105156109122,0.14061496438072402 | 3,219 |
Sterol biosynthetic process | 8 | 27 | 2.397549 | 0.016505 | Q9H2C2,Q6P1A2,Q03426,Q16850,Q15392,P54646,Q14739,Q15800 | Processes and pathways | GO Biological process | msigdb_gobp | 326,204,141,76,61,278,56,29 | 2415,894,2041,2474,1159,1836,915,1325,2873,642,2085,278,2998,141,2576,1617,56,515,2464,61,2804,29,76,204,326,391,1936 | -0.5313926522763559,0.30681128083133596,-0.3477095307450096,-0.5687820738676072,0.12377336021763811,-0.23998215837100623,0.2903690579322796,0.02184122951698084,-0.8764104949654021,0.548974178419281,-0.3658405952562187,1.2600798177392025,-1.0770728414740884,1.9256117441147356,-0.6252922481428479,-0.13400802540056259,2.739402554629938,0.7060156085430525,-0.5500592938652186,2.6906403531600036,-0.7980226823314418,3.2366995159470866,2.579971557206447,1.5579205959049545,1.1289371667707588,0.9655856472779832,-0.2756922953883126 | 3,219 |
Tclin | 18 | 90 | 2.372035 | 0.01769 | O43924,Q99720,Q06203,O75306,P62942,O43676,Q13509,P20618,Q9Y6M9,P38435,P00374,Q86Y39,P00813,P48735,Q9Y2I1,P03886,P49721,P28074 | Drugs and Diseases | Pharos IDG Category | pharos_protein_category | 258,130,63,190,387,7,292,75,238,332,145,311,341,23,184,57,28,317 | 2653,871,2654,7,2736,258,799,190,2377,1459,537,1679,895,1945,1155,1759,145,667,2894,341,57,897,571,1078,2149,1004,2657,384,831,1158,2630,2338,2962,1682,2189,2631,2693,1496,1287,1836,937,1804,75,3129,2112,1211,2781,1978,317,3174,2191,1185,2572,332,1725,23,28,2635,744,644,1060,671,2164,1380,387,1011,1987,1816,63,1217,2802,292,2317,1063,2748,2432,1412,2559,311,924,2093,130,1516,1824,472,1309,1255,1792,184,238 | -0.6823259973888944,0.32321507233725794,-0.6823259973888944,4.151275569658641,-0.7398977686794529,1.3176718798343572,0.3884511119152299,1.6134312131752497,-0.5127816595838254,-0.06429240403855782,0.6748753590501604,-0.16914305785560818,0.30681128083133596,-0.29362137810344713,0.12377336021763811,-0.20446677062676033,1.9122768063716753,0.517155278900476,-0.9159960560023168,1.084728683067828,2.7272360837614658,0.30681128083133596,0.627916326361481,0.17417480799747104,-0.4022577865800413,0.2242105156109122,-0.6823259973888944,0.9655856472779832,0.3559084044891777,0.12377336021763811,-0.663255694292154,-0.49422583330773395,-0.9959765127527764,-0.16914305785560818,-0.42054478130569956,-0.663255694292154,-0.7014560751754394,-0.0816528898016005,0.038936518919033984,-0.23998215837100623,0.27388813909007026,-0.22220031488448316,2.592334336196873,-1.5231422110485722,-0.3840232035503077,0.08996530109043266,-0.7785852884708848,-0.3116003386120246,1.143617604242851,-2.083758514401128,-0.42054478130569956,0.10689023937979268,-0.6252922481428479,1.1142289703794899,-0.1867811438681572,3.3628016428383716,3.2597485190360773,-0.663255694292154,0.4369871407324282,0.548974178419281,0.19089363138798773,0.517155278900476,-0.4022577865800413,-0.0124798039226905,0.9655856472779832,0.2242105156109122,-0.3116003386120246,-0.22220031488448316,2.666162311535732,0.08996530109043266,-0.7980226823314418,1.2166087034830142,-0.4757246978649692,0.19089363138798773,-0.7398977686794529,-0.5313926522763559,-0.0297061989992813,-0.6063980432373821,1.1582704354775262,0.2903690579322796,-0.3658405952562187,2.0183777919842116,-0.0816528898016005,-0.22220031488448316,0.8139874535706313,0.038936518919033984,0.07299824094238225,-0.20446677062676033,1.6685697660706003,1.3748498787678702 | 3,219 |
Organic hydroxy compound biosynthetic process | 17 | 57 | 2.371522 | 0.017715 | O15269,Q9UBM7,Q16822,Q9H2C2,Q86SQ9,O14734,P35270,P04062,Q13510,Q03426,Q6P1A2,Q16850,P00374,Q15392,P54646,Q14739,Q15800 | Processes and pathways | GO Biological process | msigdb_gobp | 473,391,65,326,446,328,9,105,419,141,204,76,145,61,278,56,29 | 3103,328,1030,473,892,2415,894,1564,2041,145,2474,105,1004,3012,1159,1836,915,2270,832,1839,875,1979,9,1325,2873,642,2085,278,1891,2998,141,419,2576,1617,56,515,2464,61,2804,29,65,76,204,446,2999,2095,1276,3018,2845,326,1638,582,391,1936,1372,3187,2594 | -1.391961876631989,1.1142289703794899,0.2075721060916025,0.7986583902396478,0.30681128083133596,-0.5313926522763559,0.30681128083133596,-0.11651034953388262,-0.3477095307450096,1.9122768063716753,-0.5687820738676072,2.290856236991885,0.2242105156109122,-1.1180539551826354,0.12377336021763811,-0.23998215837100623,0.2903690579322796,-0.4572777844322593,0.3559084044891777,-0.23998215837100623,0.32321507233725794,-0.3116003386120246,3.991922687702279,0.02184122951698084,-0.8764104949654021,0.548974178419281,-0.3658405952562187,1.2600798177392025,-0.2578126878849311,-1.0770728414740884,1.9256117441147356,0.9053105719493667,-0.6252922481428479,-0.13400802540056259,2.739402554629938,0.7060156085430525,-0.5500592938652186,2.6906403531600036,-0.7980226823314418,3.2366995159470866,2.666162311535732,2.579971557206447,1.5579205959049545,0.859787466513618,-1.0770728414740884,-0.3658405952562187,0.05598875083654143,-1.1180539551826354,-0.837087716438348,1.1289371667707588,-0.13400802540056259,0.627916326361481,0.9655856472779832,-0.2756922953883126,0.004702563072839793,-2.31145284936535,-0.6252922481428479 | 3,219 |
Cholesterol biosynthesis | 6 | 19 | 2.371495 | 0.017716 | Q9H2C2,Q16850,Q03426,Q15392,Q14739,Q15800 | Processes and pathways | Reactome Pathways | msigdb_reactome | 326,76,141,61,56,29 | 894,1399,1836,1325,642,2998,141,2576,1617,56,515,2464,61,2804,29,76,951,326,391 | 0.30681128083133596,-0.0297061989992813,-0.23998215837100623,0.02184122951698084,0.548974178419281,-1.0770728414740884,1.9256117441147356,-0.6252922481428479,-0.13400802540056259,2.739402554629938,0.7060156085430525,-0.5500592938652186,2.6906403531600036,-0.7980226823314418,3.2366995159470866,2.579971557206447,0.27388813909007026,1.1289371667707588,0.9655856472779832 | 3,219 |
Peroxisome organization | 6 | 16 | 2.369394 | 0.017817 | Q7Z434,Q9Y5Y5,Q96HA9,O14734,O75192,P50542 | Processes and pathways | GO Biological process | msigdb_gobp | 356,197,4,328,144,498 | 1029,328,144,513,1839,875,1884,1083,498,779,356,2439,4,907,1492,197 | 0.2075721060916025,1.1142289703794899,1.9122768063716753,0.7060156085430525,-0.23998215837100623,0.32321507233725794,-0.2578126878849311,0.17417480799747104,0.7524813868036361,0.4046666118339641,1.040266161379893,-0.5313926522763559,4.256190021258573,0.30681128083133596,-0.06429240403855782,1.5995887263604394 | 3,219 |
Protein transmembrane import into intracellular organelle | 7 | 15 | 2.366442 | 0.01796 | O60830,Q9Y5Y5,O95831,Q15388,O14925,Q99595,P50542 | Processes and pathways | GO Biological process | msigdb_gobp | 32,197,392,420,111,48,498 | 111,975,32,513,848,392,873,2778,498,420,1579,2439,48,2099,197 | 2.2138676701946065,0.240809140160788,3.1788366810455857,0.7060156085430525,0.3395806940145738,0.950561610502623,0.32321507233725794,-0.7785852884708848,0.7524813868036361,0.9053105719493667,-0.11651034953388262,-0.5313926522763559,2.7999968682905996,-0.3658405952562187,1.5995887263604394 | 3,219 |
The citric acid tca cycle and respiratory electron transport | 18 | 103 | 2.365053 | 0.018027 | P22695,O75306,O75964,P21796,O43676,Q99643,Q9Y6M9,Q86Y39,Q13423,P00846,Q9P0S2,P48735,Q9Y6N1,P03886,Q9NPL8,Q9UDW1,O14949,P53985 | Processes and pathways | Reactome Pathways | msigdb_reactome | 223,190,37,6,7,106,238,311,119,213,87,23,246,57,378,256,247,159 | 1376,2653,687,871,247,2654,7,2735,1525,2005,2736,799,190,2377,2759,1459,1076,1530,37,537,1679,895,1945,1155,2691,1759,1206,1156,213,57,1601,2078,3021,1319,1915,1801,1079,2188,1683,1760,465,2476,2658,1605,1804,1881,6,1917,223,1918,1008,2599,3174,1212,1081,524,1982,1058,2745,2911,2818,2987,23,2635,2162,778,671,1471,159,372,918,2575,2885,1988,119,2059,1293,635,2748,1412,1859,311,924,447,1992,1666,2534,106,2500,1551,928,1516,619,548,378,1309,1255,1792,87,2590,256,238,246 | -0.0124798039226905,-0.6823259973888944,0.5011930708427338,0.32321507233725794,1.3320048573799028,-0.6823259973888944,4.151275569658641,-0.7398977686794529,-0.09905875539476565,-0.3296295849566747,-0.7398977686794529,0.3884511119152299,1.6134312131752497,-0.5127816595838254,-0.7592105127205729,-0.06429240403855782,0.17417480799747104,-0.09905875539476565,2.9794613003008097,0.6748753590501604,-0.16914305785560818,0.30681128083133596,-0.29362137810344713,0.12377336021763811,-0.7014560751754394,-0.20446677062676033,0.08996530109043266,0.12377336021763811,1.5020304740736174,2.7272360837614658,-0.13400802540056259,-0.3658405952562187,-1.1386554079722488,0.02184122951698084,-0.2756922953883126,-0.22220031488448316,0.17417480799747104,-0.42054478130569956,-0.16914305785560818,-0.20446677062676033,0.8139874535706313,-0.5687820738676072,-0.6823259973888944,-0.13400802540056259,-0.22220031488448316,-0.2578126878849311,4.19336581363514,-0.2756922953883126,1.4316224032315916,-0.2756922953883126,0.2242105156109122,-0.6442446228460273,-2.083758514401128,0.08996530109043266,0.17417480799747104,0.6904619242239327,-0.3116003386120246,0.19089363138798773,-0.7398977686794529,-0.9358889993899692,-0.8175232899524535,-1.0566916417769305,3.3628016428383716,-0.663255694292154,-0.4022577865800413,0.4046666118339641,0.517155278900476,-0.06429240403855782,1.7913080821408316,0.9955452840839076,0.2903690579322796,-0.6252922481428479,-0.8961701064156942,-0.3116003386120246,2.1361981793017475,-0.3477095307450096,0.038936518919033984,0.564831320865879,-0.7398977686794529,-0.0297061989992813,-0.23998215837100623,1.1582704354775262,0.2903690579322796,0.859787466513618,-0.3116003386120246,-0.15155214072249368,-0.5875614889822378,2.2780713578916147,-0.5687820738676072,-0.09905875539476565,0.2903690579322796,-0.0816528898016005,0.5806538884509506,0.6748753590501604,0.9955452840839076,0.038936518919033984,0.07299824094238225,-0.20446677062676033,2.455409687353435,-0.6252922481428479,1.3320048573799028,1.3748498787678702,1.3463120934073578 | 3,219 |
Abnormal activity of mitochondrial respiratory chain | 13 | 58 | 2.358985 | 0.018325 | O75306,Q9UBX3,O43676,Q9Y584,Q70HW3,Q9Y6M9,Q7KZN9,Q86Y39,Q9NPL8,Q96CU9,Q9P0S2,P03886,Q5T440 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 190,229,7,137,74,238,335,311,378,116,87,57,381 | 2653,7,3091,799,190,2377,1459,1649,1155,1759,57,1319,465,1804,1881,1917,3174,2157,1212,2818,1652,2635,671,3123,1471,2605,2355,1412,1579,2888,381,74,335,311,924,1666,926,116,1630,2442,382,928,1516,811,1905,619,378,1309,1255,1792,87,2590,229,1340,2472,137,2815,238 | -0.6823259973888944,4.151275569658641,-1.348931336259688,0.3884511119152299,1.6134312131752497,-0.5127816595838254,-0.06429240403855782,-0.15155214072249368,0.12377336021763811,-0.20446677062676033,2.7272360837614658,0.02184122951698084,0.8139874535706313,-0.22220031488448316,-0.2578126878849311,-0.2756922953883126,-2.083758514401128,-0.4022577865800413,0.08996530109043266,-0.8175232899524535,-0.15155214072249368,-0.663255694292154,0.517155278900476,-1.479059046842797,-0.06429240403855782,-0.6442446228460273,-0.49422583330773395,-0.0297061989992813,-0.11651034953388262,-0.8961701064156942,0.9805801487420218,2.6046804013362,1.1142289703794899,1.1582704354775262,0.2903690579322796,-0.15155214072249368,0.2903690579322796,2.175119142227216,-0.13400802540056259,-0.5313926522763559,0.9805801487420218,0.2903690579322796,-0.0816528898016005,0.3884511119152299,-0.2578126878849311,0.5806538884509506,0.9955452840839076,0.038936518919033984,0.07299824094238225,-0.20446677062676033,2.455409687353435,-0.6252922481428479,1.4032863000627067,0.02184122951698084,-0.5500592938652186,1.952219165715867,-0.7980226823314418,1.3748498787678702 | 3,219 |
Abnormality of the mitochondrion | 25 | 99 | 2.356292 | 0.018458 | Q99757,O43676,Q9Y584,P12235,Q4J6C6,Q86Y39,P40939,P03886,O75306,O43772,Q70HW3,Q7KZN9,P00846,Q9P0S2,P13073,P35637,Q9UBX3,Q9Y6M9,Q16836,P50542,Q96CU9,Q9NPL8,Q7LG56,Q5T440,P23786 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 382,7,137,393,294,311,432,57,190,68,74,335,213,87,465,96,229,238,113,498,116,378,500,381,126 | 1376,1029,2653,7,3091,68,799,190,2377,1459,1649,1076,1155,1759,1156,213,57,1319,1801,2188,1760,3097,393,465,2476,1804,1881,1917,2341,126,1978,3174,2157,1212,96,2634,2745,432,2818,1652,657,1984,2635,498,2764,671,3123,1471,2389,1728,2605,984,1140,2355,635,1412,113,1579,1268,294,2888,381,2864,74,335,500,2826,311,924,1666,2211,926,116,1630,2442,2614,2845,382,1370,928,1516,528,907,811,1905,619,378,1309,1255,1792,87,2590,229,1340,2472,999,137,2815,238 | -0.0124798039226905,0.2075721060916025,-0.6823259973888944,4.151275569658641,-1.348931336259688,2.653898835377378,0.3884511119152299,1.6134312131752497,-0.5127816595838254,-0.06429240403855782,-0.15155214072249368,0.17417480799747104,0.12377336021763811,-0.20446677062676033,0.12377336021763811,1.5020304740736174,2.7272360837614658,0.02184122951698084,-0.22220031488448316,-0.42054478130569956,-0.20446677062676033,-1.3704042682529525,0.950561610502623,0.8139874535706313,-0.5687820738676072,-0.22220031488448316,-0.2578126878849311,-0.2756922953883126,-0.49422583330773395,2.0446992086793294,-0.3116003386120246,-2.083758514401128,-0.4022577865800413,0.08996530109043266,2.3671810512426905,-0.663255694292154,-0.7398977686794529,0.8901666692591385,-0.8175232899524535,-0.15155214072249368,0.5330822391938458,-0.3116003386120246,-0.663255694292154,0.7524813868036361,-0.7592105127205729,0.517155278900476,-1.479059046842797,-0.06429240403855782,-0.5127816595838254,-0.1867811438681572,-0.6442446228460273,0.240809140160788,0.14061496438072402,-0.49422583330773395,0.564831320865879,-0.0297061989992813,2.2138676701946065,-0.11651034953388262,0.05598875083654143,1.2166087034830142,-0.8961701064156942,0.9805801487420218,-0.856716576558732,2.6046804013362,1.1142289703794899,0.7524813868036361,-0.8175232899524535,1.1582704354775262,0.2903690579322796,-0.15155214072249368,-0.42054478130569956,0.2903690579322796,2.175119142227216,-0.13400802540056259,-0.5313926522763559,-0.6442446228460273,-0.837087716438348,0.9805801487420218,0.004702563072839793,0.2903690579322796,-0.0816528898016005,0.6904619242239327,0.30681128083133596,0.3884511119152299,-0.2578126878849311,0.5806538884509506,0.9955452840839076,0.038936518919033984,0.07299824094238225,-0.20446677062676033,2.455409687353435,-0.6252922481428479,1.4032863000627067,0.02184122951698084,-0.5500592938652186,0.240809140160788,1.952219165715867,-0.7980226823314418,1.3748498787678702 | 3,219 |
Negative regulation of defense response | 10 | 31 | 2.351659 | 0.01869 | P28070,P19474,Q8IXJ6,P04062,Q6P1A2,Q03426,Q16539,P46108,O43657,Q86UT6 | Processes and pathways | GO Biological process | msigdb_gobp | 260,103,8,105,204,141,302,277,182,220 | 182,3109,341,105,1184,1158,103,2781,260,3126,277,1654,3203,141,1731,1385,944,302,204,2645,1296,220,8,2360,2584,768,906,2095,2256,1200,754 | 1.6822971182433502,-1.4353350782595564,1.084728683067828,2.290856236991885,0.10689023937979268,0.12377336021763811,2.316370764790158,-0.7785852884708848,1.3176718798343572,-1.5010551895947977,1.2600798177392025,-0.15155214072249368,-2.7687415376013513,1.9256117441147356,-0.1867811438681572,-0.0124798039226905,0.27388813909007026,1.1728958117690913,1.5579205959049545,-0.663255694292154,0.038936518919033984,1.4457531575031033,4.130167490643299,-0.49422583330773395,-0.6252922481428479,0.4208452065718874,0.30681128083133596,-0.3658405952562187,-0.43888463081271056,0.10689023937979268,0.4369871407324282 | 3,219 |
Protein transmembrane transport | 10 | 28 | 2.350857 | 0.01873 | O60830,Q9NS69,Q15629,Q9Y5Y5,O95831,Q9Y584,Q15388,O14925,Q99595,P50542 | Processes and pathways | GO Biological process | msigdb_gobp | 32,67,97,197,392,137,420,111,48,498 | 111,975,32,2301,513,848,392,873,2778,834,981,498,2667,2555,2519,2462,420,97,1579,3015,2439,751,48,2099,67,909,137,197 | 2.2138676701946065,0.240809140160788,3.1788366810455857,-0.4757246978649692,0.7060156085430525,0.3395806940145738,0.950561610502623,0.32321507233725794,-0.7785852884708848,0.3559084044891777,0.240809140160788,0.7524813868036361,-0.6823259973888944,-0.6063980432373821,-0.5875614889822378,-0.5500592938652186,0.9053105719493667,2.3671810512426905,-0.11651034953388262,-1.1180539551826354,-0.5313926522763559,0.4369871407324282,2.7999968682905996,-0.3658405952562187,2.666162311535732,0.30681128083133596,1.952219165715867,1.5995887263604394 | 3,219 |
Translocase | 6 | 22 | 2.34506 | 0.019024 | O75306,Q03518,P08183,Q13423,P03886,Q9HD20 | Functions | Protein Atlas Molecular function | protein_atlas_molecular_function | 190,240,273,119,57,122 | 799,190,1459,1156,57,1078,1601,273,1915,1107,1804,1007,3174,1884,1843,2635,374,240,1772,119,1625,122 | 0.3884511119152299,1.6134312131752497,-0.06429240403855782,0.12377336021763811,2.7272360837614658,0.17417480799747104,-0.13400802540056259,1.2745171327387752,-0.2756922953883126,0.15741534907558857,-0.22220031488448316,0.2242105156109122,-2.083758514401128,-0.2578126878849311,-0.23998215837100623,-0.663255694292154,0.9955452840839076,1.3605937226731146,-0.20446677062676033,2.1361981793017475,-0.13400802540056259,2.084031409919309 | 3,219 |
Parkinsons disease | 10 | 59 | 2.344537 | 0.019051 | P45880,O75306,P21796,O43676,Q99643,Q9Y6M9,P00846,Q9UDW1,P03886,P22695 | Processes and pathways | KEGG Pathways | msigdb_kegg | 33,190,6,7,106,238,213,256,57,223 | 2653,687,871,247,775,2654,7,2736,799,190,2377,1459,1530,537,1679,895,1945,1155,1759,1156,213,57,1286,1601,1915,1079,1683,393,1209,465,386,2658,1605,1804,1881,6,1917,1840,223,1008,2599,3174,1212,1081,1982,33,2987,2635,671,1438,2720,2748,1412,3018,106,256,1396,3163,238 | -0.6823259973888944,0.5011930708427338,0.32321507233725794,1.3320048573799028,0.4046666118339641,-0.6823259973888944,4.151275569658641,-0.7398977686794529,0.3884511119152299,1.6134312131752497,-0.5127816595838254,-0.06429240403855782,-0.09905875539476565,0.6748753590501604,-0.16914305785560818,0.30681128083133596,-0.29362137810344713,0.12377336021763811,-0.20446677062676033,0.12377336021763811,1.5020304740736174,2.7272360837614658,0.038936518919033984,-0.13400802540056259,-0.2756922953883126,0.17417480799747104,-0.16914305785560818,0.950561610502623,0.08996530109043266,0.8139874535706313,0.9655856472779832,-0.6823259973888944,-0.13400802540056259,-0.22220031488448316,-0.2578126878849311,4.19336581363514,-0.2756922953883126,-0.23998215837100623,1.4316224032315916,0.2242105156109122,-0.6442446228460273,-2.083758514401128,0.08996530109043266,0.17417480799747104,-0.3116003386120246,3.1788366810455857,-1.0566916417769305,-0.663255694292154,0.517155278900476,-0.046976953777104945,-0.7206464789962234,-0.7398977686794529,-0.0297061989992813,-1.1180539551826354,2.2780713578916147,1.3320048573799028,-0.0124798039226905,-1.8661637345457203,1.3748498787678702 | 3,219 |
Poor eye contact | 9 | 40 | 2.343971 | 0.01908 | Q9UHX1,O75306,O43676,Q9Y6M9,Q06787,Q86Y39,Q9NPL8,Q96CU9,P03886 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 1,190,7,238,434,311,378,116,57 | 7,799,190,2377,1459,1130,1759,57,1804,3174,2080,2635,2701,1266,1571,1012,434,2279,2724,1357,1896,1173,445,311,924,2289,1666,116,2792,2442,2614,2966,1516,378,2029,1309,1255,1792,1,238 | 4.151275569658641,0.3884511119152299,1.6134312131752497,-0.5127816595838254,-0.06429240403855782,0.14061496438072402,-0.20446677062676033,2.7272360837614658,-0.22220031488448316,-2.083758514401128,-0.3658405952562187,-0.663255694292154,-0.7014560751754394,0.05598875083654143,-0.11651034953388262,0.2242105156109122,0.8901666692591385,-0.4572777844322593,-0.7206464789962234,0.004702563072839793,-0.2578126878849311,0.12377336021763811,0.859787466513618,1.1582704354775262,0.2903690579322796,-0.4572777844322593,-0.15155214072249368,2.175119142227216,-0.7785852884708848,-0.5313926522763559,-0.6442446228460273,-0.9959765127527764,-0.0816528898016005,0.9955452840839076,-0.3296295849566747,0.038936518919033984,0.07299824094238225,-0.20446677062676033,5.876223836886106,1.3748498787678702 | 3,219 |
Oxidoreductase | 45 | 158 | 2.341606 | 0.019201 | Q96LJ7,Q9UBM7,Q9BY49,Q06136,O95831,P35270,O95881,Q5VT66,P00374,Q9NZ01,Q14914,Q9H9P8,Q8NBX0,P48735,Q99536,Q8N4Q0,Q8NB78,P09601,Q15800,Q32P28,O15254,Q6UW02,Q6NUM9,Q6YN16,P40939,Q14739,Q709F0,P13674,P30519,Q15392,O75306,O75874,Q16850,Q15067,Q8IWF2,P13073,P51648,Q9UHG3,O00625,Q9BU89,P78417,P00367,Q16836,Q96CU9,Q7LG56 | Functions | Protein Atlas Molecular function | protein_atlas_molecular_function | 388,391,389,132,392,9,267,398,145,408,20,548,148,23,546,25,413,156,29,556,171,299,303,565,432,56,441,307,60,61,190,69,76,216,217,465,475,98,230,237,236,496,113,116,500 | 230,973,729,171,774,1182,2037,1458,976,2977,799,190,1459,894,69,1564,392,1834,267,1206,496,145,2474,667,2628,2740,1004,2078,1319,3012,156,1801,1760,3097,1159,1106,1287,465,307,1974,2882,937,3202,915,1804,1917,2341,1918,2659,1211,1762,3174,3156,1035,2836,2796,2233,60,759,1212,1185,3066,1883,2342,9,1162,2782,2911,432,760,2837,23,2944,1569,2050,1984,2635,2162,475,1060,1403,2084,942,2115,1691,236,2575,2606,1817,132,1574,985,2723,1617,56,20,216,61,2804,29,635,113,76,2559,556,2244,1171,398,1045,2205,303,1737,299,565,599,441,2168,500,1897,217,566,747,25,3215,413,1225,990,1664,148,2492,3059,2362,2494,2022,116,2067,388,546,2845,1862,237,683,389,1252,619,548,1965,3188,408,391,2447,2448,98,1936,1373,2141,3077,2595 | 1.3890806941306666,0.240809140160788,0.45309265624254375,1.7233434559929421,0.4046666118339641,0.10689023937979268,-0.3477095307450096,-0.06429240403855782,0.240809140160788,-1.0363823429612895,0.3884511119152299,1.6134312131752497,-0.06429240403855782,0.30681128083133596,2.6416189707121984,-0.11651034953388262,0.950561610502623,-0.23998215837100623,1.2889281552491543,0.08996530109043266,0.7524813868036361,1.9122768063716753,-0.5687820738676072,0.517155278900476,-0.663255694292154,-0.7398977686794529,0.2242105156109122,-0.3658405952562187,0.02184122951698084,-1.1180539551826354,1.8318239214365153,-0.22220031488448316,-0.20446677062676033,-1.3704042682529525,0.12377336021763811,0.15741534907558857,0.038936518919033984,0.8139874535706313,1.1582704354775262,-0.3116003386120246,-0.8961701064156942,0.27388813909007026,-2.6580428673516363,0.2903690579322796,-0.22220031488448316,-0.2756922953883126,-0.49422583330773395,-0.2756922953883126,-0.6823259973888944,0.08996530109043266,-0.20446677062676033,-2.083758514401128,-1.8425667734679056,0.2075721060916025,-0.837087716438348,-0.7980226823314418,-0.43888463081271056,2.7028550450163786,0.4208452065718874,0.08996530109043266,0.10689023937979268,-1.2638673302757721,-0.2578126878849311,-0.49422583330773395,3.991922687702279,0.12377336021763811,-0.7785852884708848,-0.9358889993899692,0.8901666692591385,0.4208452065718874,-0.837087716438348,3.3628016428383716,-0.9758785445560134,-0.11651034953388262,-0.3477095307450096,-0.3116003386120246,-0.663255694292154,-0.4022577865800413,0.7986583902396478,0.19089363138798773,-0.0297061989992813,-0.3658405952562187,0.27388813909007026,-0.3840232035503077,-0.16914305785560818,1.3748498787678702,-0.6252922481428479,-0.6442446228460273,-0.22220031488448316,1.9919755786666307,-0.11651034953388262,0.240809140160788,-0.7206464789962234,-0.13400802540056259,2.739402554629938,3.6656806041326533,1.4598592164393882,2.6906403531600036,-0.7980226823314418,3.2366995159470866,0.564831320865879,2.2138676701946065,2.579971557206447,-0.6063980432373821,0.6592557088759661,-0.43888463081271056,0.12377336021763811,0.950561610502623,0.2075721060916025,-0.42054478130569956,1.1728958117690913,-0.1867811438681572,1.2020647978678858,0.6436027674453496,0.5964421007549159,0.874992360533424,-0.4022577865800413,0.7524813868036361,-0.2578126878849311,1.4598592164393882,0.6436027674453496,0.4369871407324282,3.351404613648987,-4.50217549538397,0.9204242461273519,0.08996530109043266,0.240809140160788,-0.15155214072249368,1.8721459336914674,-0.5687820738676072,-1.2218191204266629,-0.49422583330773395,-0.5687820738676072,-0.3296295849566747,2.175119142227216,-0.3477095307450096,0.9655856472779832,0.6748753590501604,-0.837087716438348,-0.23998215837100623,1.3748498787678702,0.517155278900476,0.9655856472779832,0.07299824094238225,0.5806538884509506,0.6748753590501604,-0.29362137810344713,-2.3896111361236,0.9355078676043538,0.9655856472779832,-0.5313926522763559,-0.5313926522763559,2.3671810512426905,-0.2756922953883126,0.004702563072839793,-0.3840232035503077,-1.285011033296226,-0.6252922481428479 | 3,219 |
Cataract | 8 | 29 | 2.340509 | 0.019257 | Q15125,O76024,Q03426,Q9H6K4,O00400,P11166,P08670,Q15800 | Drugs and Diseases | Protein Atlas Disease involvement | protein_atlas_disease_involvement | 515,264,141,14,54,439,342,29 | 728,54,1151,550,264,1798,342,439,1566,2044,1887,642,2273,2278,141,515,29,2245,1505,1194,2322,2492,2362,1489,1867,2444,14,1452,867 | 0.45309265624254375,2.7515530751583857,0.12377336021763811,0.6592557088759661,1.3033130248343696,-0.22220031488448316,1.084728683067828,0.874992360533424,-0.11651034953388262,-0.3477095307450096,-0.2578126878849311,0.548974178419281,-0.4572777844322593,-0.4572777844322593,1.9256117441147356,0.7060156085430525,3.2366995159470866,-0.43888463081271056,-0.0816528898016005,0.10689023937979268,-0.4757246978649692,-0.5687820738676072,-0.49422583330773395,-0.06429240403855782,-0.23998215837100623,-0.5313926522763559,3.8734982338727697,-0.046976953777104945,0.3395806940145738 | 3,219 |
Abnormal pulmonary interstitial morphology | 6 | 29 | 2.339569 | 0.019306 | P14174,P57740,P04062,Q14108,Q8IZA0,P09601 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 3,70,105,142,90,156 | 2996,2413,1429,1033,105,156,3,3178,1467,690,2235,1569,2194,2195,70,1352,419,142,1700,1363,2398,90,2324,3145,2330,202,2332,1025,1073 | -1.0770728414740884,-0.5313926522763559,-0.046976953777104945,0.2075721060916025,2.290856236991885,1.8318239214365153,4.524257799898794,-2.1334650509701083,-0.06429240403855782,0.5011930708427338,-0.43888463081271056,-0.11651034953388262,-0.42054478130569956,-0.42054478130569956,2.6293226533158274,0.004702563072839793,0.9053105719493667,1.9256117441147356,-0.16914305785560818,0.004702563072839793,-0.5127816595838254,2.417703668148951,-0.4757246978649692,-1.6576364016996559,-0.4757246978649692,1.571833533959058,-0.4757246978649692,0.2242105156109122,0.19089363138798773 | 3,219 |
Membrane lipid biosynthetic process | 11 | 26 | 2.337653 | 0.019405 | O15269,Q06136,Q9H490,P04062,P27544,Q13510,Q99805,Q8NBX0,O43292,Q96G23,O95470 | Processes and pathways | GO Biological process | msigdb_gobp | 473,132,487,105,394,419,210,148,340,252,306 | 473,892,340,2737,306,105,2339,832,394,132,419,2432,2245,1506,148,1094,2496,252,3025,210,487,582,1425,1024,1149,1027 | 0.7986583902396478,0.30681128083133596,1.084728683067828,-0.7398977686794529,1.1582704354775262,2.290856236991885,-0.49422583330773395,0.3559084044891777,0.950561610502623,1.9919755786666307,0.9053105719493667,-0.5313926522763559,-0.43888463081271056,-0.0816528898016005,1.8721459336914674,0.17417480799747104,-0.5687820738676072,1.3320048573799028,-1.1386554079722488,1.53002344770046,0.7832978184435848,0.627916326361481,-0.0297061989992813,0.2242105156109122,0.14061496438072402,0.2242105156109122 | 3,219 |
Mitochondrial myopathy | 10 | 32 | 2.332605 | 0.019669 | O75306,O43676,P12235,Q9Y6M9,Q9Y606,Q86Y39,Q9NPL8,P00846,Q96CU9,P03886 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 190,7,393,238,462,311,378,213,116,57 | 7,1599,799,190,2377,1459,1759,1156,213,57,393,1804,3174,2635,2764,2245,500,311,924,1666,116,2614,1516,810,1905,1022,378,1309,1255,653,462,238 | 4.151275569658641,-0.13400802540056259,0.3884511119152299,1.6134312131752497,-0.5127816595838254,-0.06429240403855782,-0.20446677062676033,0.12377336021763811,1.5020304740736174,2.7272360837614658,0.950561610502623,-0.22220031488448316,-2.083758514401128,-0.663255694292154,-0.7592105127205729,-0.43888463081271056,0.7524813868036361,1.1582704354775262,0.2903690579322796,-0.15155214072249368,2.175119142227216,-0.6442446228460273,-0.0816528898016005,0.3884511119152299,-0.2578126878849311,0.2242105156109122,0.9955452840839076,0.038936518919033984,0.07299824094238225,0.548974178419281,0.8292851967373376,1.3748498787678702 | 3,219 |
Impaired proprioception | 9 | 43 | 2.332437 | 0.019678 | Q8N0X7,Q8IV08,Q9H6K4,Q9NR77,Q9Y619,O00165,P00846,O00400,P54802 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 295,234,14,49,243,244,213,54,250 | 244,54,570,1562,1525,2301,1564,2041,1719,213,2742,331,2778,2079,2383,1323,1884,2385,2479,1037,250,2115,1728,1817,434,695,1773,1293,3042,2529,1193,234,295,2362,1707,2614,841,1554,14,49,1938,243,1971 | 1.3463120934073578,2.7515530751583857,0.627916326361481,-0.11651034953388262,-0.09905875539476565,-0.4757246978649692,-0.11651034953388262,-0.3477095307450096,-0.1867811438681572,1.5020304740736174,-0.7398977686794529,1.1142289703794899,-0.7785852884708848,-0.3658405952562187,-0.5127816595838254,0.02184122951698084,-0.2578126878849311,-0.5127816595838254,-0.5687820738676072,0.2075721060916025,1.3320048573799028,-0.3840232035503077,-0.1867811438681572,-0.22220031488448316,0.8901666692591385,0.5011930708427338,-0.20446677062676033,0.038936518919033984,-1.1800840546241298,-0.5875614889822378,0.10689023937979268,1.3890806941306666,1.2166087034830142,-0.49422583330773395,-0.16914305785560818,-0.6442446228460273,0.3559084044891777,-0.09905875539476565,3.8734982338727697,2.7879095428710334,-0.2756922953883126,1.3605937226731146,-0.29362137810344713 | 3,219 |
Hormone metabolic process | 7 | 28 | 2.324294 | 0.02011 | P42892,O75844,Q6NUM9,P09455,Q9HB40,O95470,P30536 | Processes and pathways | GO Biological process | msigdb_gobp | 102,200,303,115,21,306,92 | 872,1152,200,306,1078,115,1466,937,915,92,102,2944,1403,1113,2319,1171,303,990,1664,2492,2586,2067,2845,21,1965,391,1938,3077 | 0.32321507233725794,0.12377336021763811,1.571833533959058,1.1582704354775262,0.17417480799747104,2.175119142227216,-0.06429240403855782,0.27388813909007026,0.2903690579322796,2.405099723026584,2.329100568036832,-0.9758785445560134,-0.0297061989992813,0.15741534907558857,-0.4757246978649692,0.12377336021763811,1.1728958117690913,0.240809140160788,-0.15155214072249368,-0.5687820738676072,-0.6252922481428479,-0.3477095307450096,-0.837087716438348,3.6546244885008625,-0.29362137810344713,0.9655856472779832,-0.2756922953883126,-1.285011033296226 | 3,219 |
Membrane lipid catabolic process | 6 | 11 | 2.31869 | 0.020412 | P06280,P04062,P06865,Q13510,P50897,O95470 | Processes and pathways | GO Biological process | msigdb_gobp | 384,105,330,419,22,306 | 306,105,508,384,330,2692,705,22,419,1862,1425 | 1.1582704354775262,2.290856236991885,0.7215366140730911,0.9655856472779832,1.1142289703794899,-0.7014560751754394,0.4851953858805861,3.5768907333196704,0.9053105719493667,-0.23998215837100623,-0.0297061989992813 | 3,219 |
Active transmembrane transporter activity | 20 | 77 | 2.312144 | 0.02077 | O43676,P12235,P08183,Q9Y6M7,P53985,O95139,Q15388,O00400,P03886,O75306,P16260,Q7KZN9,P13073,P98194,Q9UBX3,Q9Y6M9,Q03518,Q9UDW1,Q9HD20,P51798 | Functions | GO Molecular function | msigdb_gomf | 7,393,273,417,159,537,420,54,57,190,453,335,465,374,229,238,240,256,122,380 | 54,2653,687,2654,7,2736,2264,799,190,2377,1459,537,1679,895,1945,1131,1155,1759,1156,57,1078,2149,1286,1601,273,1005,1915,1683,393,1209,465,453,1107,1804,1007,1881,1976,3049,875,3174,1081,1884,1809,1843,1037,2635,1110,380,671,1266,159,1380,1845,374,984,555,240,1772,420,1245,2748,1412,335,724,726,1637,770,1710,122,3159,1792,229,256,1827,2713,417,238 | 2.7515530751583857,-0.6823259973888944,0.5011930708427338,-0.6823259973888944,4.151275569658641,-0.7398977686794529,-0.4572777844322593,0.3884511119152299,1.6134312131752497,-0.5127816595838254,-0.06429240403855782,0.6748753590501604,-0.16914305785560818,0.30681128083133596,-0.29362137810344713,0.14061496438072402,0.12377336021763811,-0.20446677062676033,0.12377336021763811,2.7272360837614658,0.17417480799747104,-0.4022577865800413,0.038936518919033984,-0.13400802540056259,1.2745171327387752,0.2242105156109122,-0.2756922953883126,-0.16914305785560818,0.950561610502623,0.08996530109043266,0.8139874535706313,0.8445518061819609,0.15741534907558857,-0.22220031488448316,0.2242105156109122,-0.2578126878849311,-0.3116003386120246,-1.200912870498824,0.32321507233725794,-2.083758514401128,0.17417480799747104,-0.2578126878849311,-0.22220031488448316,-0.23998215837100623,0.2075721060916025,-0.663255694292154,0.15741534907558857,0.9805801487420218,0.517155278900476,0.05598875083654143,1.7913080821408316,-0.0124798039226905,-0.23998215837100623,0.9955452840839076,0.240809140160788,0.6592557088759661,1.3605937226731146,-0.20446677062676033,0.9053105719493667,0.07299824094238225,-0.7398977686794529,-0.0297061989992813,1.1142289703794899,0.46916199239345446,0.46916199239345446,-0.13400802540056259,0.4208452065718874,-0.16914305785560818,2.084031409919309,-1.8425667734679056,-0.20446677062676033,1.4032863000627067,1.3320048573799028,-0.22220031488448316,-0.7014560751754394,0.9204242461273519,1.3748498787678702 | 3,219 |
Xerostomia | 7 | 15 | 2.309696 | 0.020905 | P35637,P07737,Q92804,P43243,P09651,Q14739,Q15165 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 96,385,136,670,586,56,154 | 2379,385,586,96,670,876,1380,1728,1140,1189,56,154,879,136,717 | -0.5127816595838254,0.9655856472779832,0.6121961750555308,2.3671810512426905,0.517155278900476,0.32321507233725794,-0.0124798039226905,-0.1867811438681572,0.14061496438072402,0.10689023937979268,2.739402554629938,1.845285994530105,0.32321507233725794,1.9654918389860268,0.4851953858805861 | 3,219 |
Abnormality of extrapyramidal motor function | 19 | 78 | 2.309299 | 0.020927 | Q99720,P35270,P12235,Q9H6K4,Q96IX5,Q9H9P8,Q6DKK2,Q06787,P11166,Q6Y7W6,Q86SQ9,P06865,Q14353,P98175,P35637,P04062,P07602,Q7LG56,O14949 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 130,9,393,14,399,548,163,434,439,310,446,330,468,343,96,105,112,500,247 | 247,775,1105,799,1678,1152,2455,873,2337,105,936,1879,330,112,2692,1431,439,1496,393,1802,2780,1263,705,1566,2152,1805,2553,1081,743,9,1533,96,2160,1921,2701,1571,1728,1654,1891,2314,343,1188,3034,2799,434,543,1140,1189,468,1191,2888,163,2320,310,500,446,399,2095,1707,2614,3018,130,1421,928,1489,1554,14,548,2029,3102,795,1312,2000,1938,2182,754,910,999 | 1.3320048573799028,0.4046666118339641,0.15741534907558857,0.3884511119152299,-0.16914305785560818,0.12377336021763811,-0.5500592938652186,0.32321507233725794,-0.49422583330773395,2.290856236991885,0.27388813909007026,-0.2578126878849311,1.1142289703794899,2.2138676701946065,-0.7014560751754394,-0.046976953777104945,0.874992360533424,-0.0816528898016005,0.950561610502623,-0.22220031488448316,-0.7785852884708848,0.05598875083654143,0.4851953858805861,-0.11651034953388262,-0.4022577865800413,-0.22220031488448316,-0.6063980432373821,0.17417480799747104,0.4369871407324282,3.991922687702279,-0.09905875539476565,2.3671810512426905,-0.4022577865800413,-0.2756922953883126,-0.7014560751754394,-0.11651034953388262,-0.1867811438681572,-0.15155214072249368,-0.2578126878849311,-0.4757246978649692,1.084728683067828,0.10689023937979268,-1.159331839849001,-0.7980226823314418,0.8901666692591385,0.6748753590501604,0.14061496438072402,0.10689023937979268,0.8139874535706313,0.10689023937979268,-0.8961701064156942,1.7777592561307913,-0.4757246978649692,1.1582704354775262,0.7524813868036361,0.859787466513618,0.950561610502623,-0.3658405952562187,-0.16914305785560818,-0.6442446228460273,-1.1180539551826354,2.0183777919842116,-0.0297061989992813,0.2903690579322796,-0.06429240403855782,-0.09905875539476565,3.8734982338727697,0.6748753590501604,-0.3296295849566747,-1.3704042682529525,0.4046666118339641,0.038936518919033984,-0.3116003386120246,-0.2756922953883126,-0.4022577865800413,0.4369871407324282,0.30681128083133596,0.240809140160788 | 3,219 |
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