term stringlengths 2 121 | overlap int64 6 281 | setsize int64 7 499 | score float64 1.96 10.6 | pval float64 0 0.05 | edge stringlengths 41 1.97k | type stringclasses 5 values | subtype stringclasses 24 values | subtype_key stringclasses 24 values | edge_idxs stringlengths 11 1.17k | ann_idxs stringlengths 19 2.31k | ann_vals stringlengths 124 9.94k | sig_size int64 2.2k 3.73k |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Pore complex | 6 | 9 | 2.613135 | 0.008972 | Q07812,Q9Y277,P21796,O96008,P45880,P12235 | Localization | GO Cellular component | msigdb_gocc | 354,66,70,300,50,158 | 300,403,158,70,1733,50,2049,354,66 | 1.2433090578397443,0.9669038074280564,1.7853014752695062,2.5995589664368004,-0.19444171825613035,2.907101064760008,-0.3430078305713249,1.0779181486196767,2.6382243688422604 | 3,220 |
Maintenance of protein localization in organelle | 8 | 15 | 2.602163 | 0.009264 | P24390,P30536,O43292,P52789,Q13438,O15258,Q9UH99,O43731 | Processes and pathways | GO Biological process | msigdb_gobp | 164,197,137,171,362,110,275,92 | 110,137,92,359,886,164,197,601,1990,171,569,2892,362,2326,275 | 2.0380155210262614,1.8920646818638314,2.2092672490607383,1.06407470918364,0.3161453056172049,1.7451289416289844,1.570171930412102,0.6159377018946759,-0.313194785097642,1.704881209746608,0.6583862932184593,-0.8886275567160946,1.06407470918364,-0.47779711418441184,1.3255071355722057 | 3,220 |
oxidase | 9 | 14 | 2.597515 | 0.00939 | P14406,P15954,O75880,P13073,Q15800,Q8NB78,Q6ZRP7,O14548,P20674 | Functions | Panther Protein class | panther_protein_class | 2,577,298,112,177,723,631,369,349 | 369,1253,1764,1376,298,2043,112,2,577,349,730,177,631,723 | 1.0224874166341895,0.055331969068424594,-0.20924260096857328,-0.01777473199075143,1.2433090578397443,-0.3430078305713249,2.0380155210262614,4.3291217026971225,0.6442470592213966,1.0917521341398324,0.4594902255077705,1.6780073418899184,0.5875869648575647,0.473765489840932 | 3,220 |
Monooxygenase activity | 6 | 10 | 2.581393 | 0.00984 | Q9BU89,Q6UW02,Q15800,Q16850,P30519,P09601 | Functions | GO Molecular function | msigdb_gomf | 163,230,177,215,24,152 | 2873,525,152,24,1706,229,177,215,230,163 | -0.873231681277683,0.7289291660118463,1.8120416545482296,3.4981163078685293,-0.1796530741697238,1.4617845329488237,1.6780073418899184,1.5160479135785023,1.4617845329488237,1.7585281147256453 | 3,220 |
Triglyceride metabolic process | 8 | 11 | 2.579916 | 0.009882 | Q96N66,Q8WTV0,Q96AD5,Q92604,O94830,P50416,Q8NCG7,Q9UBV2 | Processes and pathways | GO Biological process | msigdb_gobp | 594,373,566,340,402,213,350,413 | 402,585,213,1058,1268,350,373,340,566,594,413 | 0.9669038074280564,0.6300975384411448,1.5160479135785023,0.1861959397352981,0.055331969068424594,1.0917521341398324,1.0224874166341895,1.1193918429266982,0.6725152692738572,0.6300975384411448,0.9529838262623884 | 3,220 |
mitochondrial carrier protein | 6 | 8 | 2.577123 | 0.009963 | Q6NUK1,Q9NZJ7,Q70HW3,P16260,Q9BSK2,Q9HC21 | Functions | Panther Protein class | panther_protein_class | 290,140,47,176,210,310 | 176,703,290,47,210,310,140,377 | 1.6780073418899184,0.4880301099656987,1.2844490111299678,2.9706691886854455,1.5295919290991515,1.215836649167216,1.8920646818638314,1.0224874166341895 | 3,220 |
Organophosphate ester transmembrane transporter activity | 10 | 12 | 2.571031 | 0.01014 | Q9H2D1,Q6NUK1,Q8TB61,Q9BSK2,Q9HC21,P05141,P12236,P12235,O43808,O00400 | Functions | GO Molecular function | msigdb_gomf | 99,290,104,210,310,403,185,158,317,62 | 62,317,403,158,185,426,3175,290,104,210,99,310 | 2.6768253453241613,1.1883274006382527,0.9669038074280564,1.7853014752695062,1.6241579565962334,0.9251147879781412,-1.9556055796511111,1.2844490111299678,2.090849287701112,1.5295919290991515,2.143557307496829,1.215836649167216 | 3,220 |
Nucleotide transmembrane transporter activity | 10 | 12 | 2.571031 | 0.01014 | Q9H2D1,Q6NUK1,Q8TB61,Q9BSK2,Q9HC21,P05141,P12236,P12235,O43808,O00400 | Functions | GO Molecular function | msigdb_gomf | 99,290,104,210,310,403,185,158,317,62 | 62,317,403,158,185,426,3175,290,104,210,99,310 | 2.6768253453241613,1.1883274006382527,0.9669038074280564,1.7853014752695062,1.6241579565962334,0.9251147879781412,-1.9556055796511111,1.2844490111299678,2.090849287701112,1.5295919290991515,2.143557307496829,1.215836649167216 | 3,220 |
Mitochondrial protein import | 25 | 36 | 2.563965 | 0.010348 | Q8N4H5,O43615,P08574,Q9NS69,Q9Y584,P51553,P62072,O14925,P12235,O60830,Q13505,Q9NX63,O96008,Q9Y5J9,P12236,Q99595,Q9Y512,O75746,P21796,Q9Y5J6,Q9Y276,O75431,O94826,Q15388,Q10713 | Processes and pathways | Reactome Pathways | msigdb_reactome | 4,520,522,21,23,661,26,29,158,37,41,557,300,181,185,64,323,575,70,346,477,348,598,620,361 | 29,520,37,2464,348,1451,575,598,300,1403,522,1987,158,185,70,1836,1736,661,26,361,41,620,674,1650,4,64,2408,1343,21,557,778,477,323,23,346,181 | 3.361075633693647,0.7430072800978298,3.2106974716483787,-0.5682407864248026,1.0917521341398324,-0.06177987491864927,0.6442470592213966,0.6159377018946759,1.2433090578397443,-0.03243127960906722,0.7430072800978298,-0.313194785097642,1.7853014752695062,1.6241579565962334,2.5995589664368004,-0.23888123943057013,-0.19444171825613035,0.544982758232892,3.448371427949981,1.06407470918364,3.1099250993926355,0.6017675204564823,0.5307604103957996,-0.15011234602282414,4.3291217026971225,2.663965486017274,-0.5229597504510352,0.011503046829603012,3.5973077301556384,0.6866340160886069,0.4166002588713612,0.8412731718875827,1.174558901603863,3.5725469272262074,1.1055766906461557,1.6510996458924831 | 3,220 |
Mitochondrial calcium ion homeostasis | 8 | 12 | 2.516311 | 0.011859 | P51572,Q9H4I9,Q8WWC4,Q8IYU8,Q8NE86,Q9BPX6,Q96AQ8,O95202 | Processes and pathways | GO Biological process | msigdb_gobp | 485,38,172,175,406,342,282,124 | 124,2491,485,1117,602,175,406,172,282,342,38,1281 | 1.9717947009390235,-0.5833609844142108,0.8132470889449575,0.14267746792433023,0.6159377018946759,1.6914484940680552,0.9669038074280564,1.704881209746608,1.3118301474062795,1.1193918429266982,3.2106974716483787,0.055331969068424594 | 3,220 |
Snap receptor activity | 9 | 18 | 2.512286 | 0.011995 | O14653,O95249,O75396,Q9NZ43,O60499,Q12846,P56962,O43752,Q9P2W9 | Functions | GO Molecular function | msigdb_gomf | 225,73,452,314,118,372,214,249,31 | 2593,225,1109,2187,249,118,452,73,1429,772,214,372,562,672,1216,314,31,1497 | -0.6439755827313389,1.4753635194517039,0.14267746792433023,-0.4177623935728443,1.4073803914068117,2.0115511185478705,0.8692596729318535,2.52203320891506,-0.04709964827475354,0.4166002588713612,1.5160479135785023,1.0224874166341895,0.6725152692738572,0.5307604103957996,0.08449317262514162,1.2020866418225167,3.3485794389162113,-0.07647199667296625 | 3,220 |
Snare interactions in vesicular transport | 9 | 18 | 2.512286 | 0.011995 | O14653,O95249,O75396,Q9NZ43,O60499,Q12846,P56962,O43752,Q9P2W9 | Processes and pathways | KEGG Pathways | msigdb_kegg | 225,73,452,314,118,372,214,249,31 | 2593,225,1109,2187,249,118,452,73,1429,772,214,372,562,672,1216,314,31,1497 | -0.6439755827313389,1.4753635194517039,0.14267746792433023,-0.4177623935728443,1.4073803914068117,2.0115511185478705,0.8692596729318535,2.52203320891506,-0.04709964827475354,0.4166002588713612,1.5160479135785023,1.0224874166341895,0.6725152692738572,0.5307604103957996,0.08449317262514162,1.2020866418225167,3.3485794389162113,-0.07647199667296625 | 3,220 |
mitochondria | 9 | 12 | 2.50945 | 0.012092 | O94826,Q9Y277,P21796,Q8IWA4,Q15388,Q9NR31,P45880,Q14318,Q969Q5 | Localization | OpenCell Localization | opencell_localization | 598,66,70,364,620,467,50,536,191 | 598,1201,70,50,536,620,364,191,694,467,809,66 | 0.6159377018946759,0.08449317262514162,2.5995589664368004,2.907101064760008,0.7148409361035052,0.6017675204564823,1.06407470918364,1.6106743124643152,0.5022841164890406,0.8552713566510017,0.38795315862879387,2.6382243688422604 | 3,220 |
Calcium transport | 7 | 10 | 2.481415 | 0.013086 | Q9H4I9,Q8NE86,P16615,Q9BPX6,Q96AQ8,Q9UM00,O95202 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 38,406,179,342,282,316,124 | 124,179,680,429,406,282,342,38,2462,316 | 1.9717947009390235,1.6510996458924831,0.5165275398650023,0.9251147879781412,0.9669038074280564,1.3118301474062795,1.1193918429266982,3.2106974716483787,-0.553133878075549,1.2020866418225167 | 3,220 |
oxygenase | 6 | 9 | 2.478367 | 0.013199 | Q6UW02,Q14534,Q16850,P30519,P09601,Q9BV57 | Functions | Panther Protein class | panther_protein_class | 230,229,215,24,152,351 | 525,152,24,229,215,230,1364,351,2065 | 0.7289291660118463,1.8120416545482296,3.4981163078685293,1.4617845329488237,1.5160479135785023,1.4617845329488237,-0.003129968688779517,1.0917521341398324,-0.3430078305713249 | 3,220 |
Carbohydrate derivative transport | 12 | 16 | 2.473643 | 0.013374 | Q6NUK1,L0R6Q1,Q8TB61,Q9NZJ7,Q8WTV0,Q9HC21,P05141,O00400,P12236,O43808,P12235,Q08722 | Processes and pathways | GO Biological process | msigdb_gobp | 290,102,104,140,373,310,403,62,185,317,158,255 | 102,62,317,403,638,158,185,426,3175,3176,255,290,104,373,310,140 | 2.090849287701112,2.6768253453241613,1.1883274006382527,0.9669038074280564,0.5733960056844266,1.7853014752695062,1.6241579565962334,0.9251147879781412,-1.9556055796511111,-1.9886334261219616,1.3937571960734862,1.2844490111299678,2.090849287701112,1.0224874166341895,1.215836649167216,1.8920646818638314 | 3,220 |
Class i peroxisomal membrane protein import | 10 | 13 | 2.465773 | 0.013672 | Q5T8D3,O75381,P56589,Q8TB36,P51648,Q9Y5Y5,P40855,P33897,Q9NR77,O43808 | Processes and pathways | Reactome Pathways | msigdb_reactome | 675,370,331,593,44,174,587,426,443,317 | 317,370,1008,426,587,44,331,675,875,593,748,443,174 | 1.1883274006382527,1.0224874166341895,0.2151517460221033,0.9251147879781412,0.6300975384411448,3.059380306475877,1.1331976156562682,0.5307604103957996,0.330528729857457,0.6300975384411448,0.4452042862052327,0.8972068072481052,1.704881209746608 | 3,220 |
Gated channel activity | 8 | 14 | 2.463908 | 0.013743 | Q9Y277,Q4KMQ2,Q96ER9,P21796,P45880,Q9Y696,Q9NW15,Q9C0H2 | Functions | GO Molecular function | msigdb_gomf | 66,545,325,70,50,218,151,606 | 1427,2491,1113,70,50,2081,2167,545,325,655,606,151,66,218 | -0.04709964827475354,-0.5833609844142108,0.14267746792433023,2.5995589664368004,2.907101064760008,-0.35793329427295245,-0.4027859480941016,0.7007425622241883,1.160781120599868,0.5591946133780552,0.6159377018946759,1.8253993507524382,2.6382243688422604,1.5160479135785023 | 3,220 |
Oxidase | 9 | 21 | 2.46132 | 0.013843 | O43169,O15254,P14406,P15954,O75880,Q15800,O14548,Q15067,P20674 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 0,192,2,577,298,177,369,537,349 | 369,192,1093,0,1253,1376,298,2043,1074,1474,2,577,349,2045,730,1287,537,177,631,804,1196 | 1.0224874166341895,1.5971821074339623,0.15719497235672153,4.3291217026971225,0.055331969068424594,-0.01777473199075143,1.2433090578397443,-0.3430078305713249,0.1717011182043829,-0.07647199667296625,4.3291217026971225,0.6442470592213966,1.0917521341398324,-0.3430078305713249,0.4594902255077705,0.04073397966432928,0.7148409361035052,1.6780073418899184,0.5875869648575647,0.38795315862879387,0.09905645771621088 | 3,220 |
Chloride transport | 8 | 13 | 2.457689 | 0.013983 | Q9UHG3,P54105,P08183,P30536,Q4KMQ2,Q9Y696,Q9NW15,Q9C0H2 | Processes and pathways | GO Biological process | msigdb_gobp | 224,160,484,197,545,218,151,606 | 1427,484,197,2081,2167,160,1208,545,653,606,151,224,218 | -0.04709964827475354,0.8132470889449575,1.570171930412102,-0.35793329427295245,-0.4027859480941016,1.7719189526049448,0.08449317262514162,0.7007425622241883,0.5591946133780552,0.6159377018946759,1.8253993507524382,1.4889337304892023,1.5160479135785023 | 3,220 |
Intrinsic component of peroxisomal membrane | 6 | 9 | 2.444771 | 0.014494 | O75192,P56589,Q96HA9,Q9Y5Y5,P33897,O43808 | Localization | GO Cellular component | msigdb_gocc | 96,331,109,174,426,317 | 460,317,96,426,331,1655,748,109,174 | 0.8552713566510017,1.1883274006382527,2.1567147995211386,0.9251147879781412,1.1331976156562682,-0.15011234602282414,0.4452042862052327,2.0512358149832477,1.704881209746608 | 3,220 |
Very long chain fatty acid metabolic process | 9 | 13 | 2.443488 | 0.014546 | Q6P1M0,P33897,P33121,O14975,Q9NZ01,Q9UKU0,Q15067,Q9P035,Q6Y1H2 | Processes and pathways | GO Biological process | msigdb_gobp | 735,426,585,460,769,25,537,382,641 | 460,1139,1008,585,426,771,1305,537,735,641,769,382,25 | 0.8552713566510017,0.12814857045825676,0.2151517460221033,0.6300975384411448,0.9251147879781412,0.4166002588713612,0.02612435090038817,0.7148409361035052,0.4594902255077705,0.5733960056844266,0.43090764101721113,1.0086059102080356,3.4981163078685293 | 3,220 |
Intrinsic component of mitochondrial membrane | 41 | 55 | 2.438645 | 0.014742 | O95563,Q9P0S2,Q8N8Q8,Q5XKP0,Q9H9P8,Q8NE86,Q9Y6N1,Q96AQ8,Q9BUB7,O14925,P12235,Q9H4I9,O60830,Q13505,Q15070,Q9NX63,O96008,O75880,Q9HC21,Q99595,Q9Y512,Q96ER9,Q96NB2,Q9BUR5,Q9H3K2,Q53H12,Q8TB36,Q9UH62,Q8IXI1,Q9BPX6,P57105,Q9UG56,P50416,O75431,O94826,Q16891,Q8IWA4,Q9BWH2,Q6P4A7,Q9Y2R0,Q6UXV4 | Localization | GO Cellular component | msigdb_gocc | 129,10,139,16,408,406,148,282,412,29,158,38,37,41,42,557,300,298,310,64,323,325,457,71,69,204,593,468,591,342,84,212,213,348,598,602,364,500,378,122,250 | 29,1253,37,348,298,598,1201,129,300,158,1006,1736,213,84,703,41,42,620,1514,602,204,889,16,378,250,364,591,1585,139,406,593,282,325,457,64,342,412,71,500,936,69,38,678,408,310,3160,809,557,10,212,468,122,1281,323,148 | 3.361075633693647,0.055331969068424594,3.2106974716483787,1.0917521341398324,1.2433090578397443,0.6159377018946759,0.08449317262514162,1.9452503290298178,1.2433090578397443,1.7853014752695062,0.2151517460221033,-0.19444171825613035,1.5160479135785023,2.3661898889393695,0.4880301099656987,3.1099250993926355,3.0972988744230174,0.6017675204564823,-0.09117605087284349,0.6159377018946759,1.5566539160615283,0.3161453056172049,3.7822378308851308,1.0086059102080356,1.4073803914068117,1.06407470918364,0.6300975384411448,-0.1206201069740683,1.8920646818638314,0.9669038074280564,0.6300975384411448,1.3118301474062795,1.160781120599868,0.8692596729318535,2.663965486017274,1.1193918429266982,0.9529838262623884,2.5995589664368004,0.7992191364595662,0.28734545070934525,2.62534308033295,3.2106974716483787,0.5307604103957996,0.9669038074280564,1.215836649167216,-1.7752677675371011,0.38795315862879387,0.6866340160886069,4.3291217026971225,1.5295919290991515,0.8552713566510017,1.9850548401175079,0.055331969068424594,1.174558901603863,1.8387488109229877 | 3,220 |
Cardiac muscle contraction | 12 | 21 | 2.437763 | 0.014778 | P14406,P15954,P22695,P08574,O14949,P13073,P05023,P16615,P09669,Q9UDW1,O14548,P20674 | Processes and pathways | KEGG Pathways | msigdb_kegg | 2,577,329,522,13,112,526,179,371,120,369,349 | 369,13,1598,526,944,2334,522,2282,371,2043,112,2,1326,577,179,349,329,785,629,2496,120 | 1.0224874166341895,4.196501680534049,-0.13536018457472698,0.7289291660118463,0.27292895481255514,-0.4928382444842881,0.7430072800978298,-0.46276900728826853,1.0224874166341895,-0.3430078305713249,2.0380155210262614,4.3291217026971225,0.011503046829603012,0.6442470592213966,1.6510996458924831,1.0917521341398324,1.1331976156562682,0.4022821085379622,0.5875869648575647,-0.5833609844142108,2.0115511185478705 | 3,220 |
Mitophagy | 6 | 11 | 2.428668 | 0.015154 | O94826,Q8N4H5,P21796,Q8IWA4,O96008,Q9NS69 | Processes and pathways | Reactome Pathways | msigdb_reactome | 598,4,70,364,300,21 | 598,1201,300,1865,70,1507,620,364,4,911,21 | 0.6159377018946759,0.08449317262514162,1.2433090578397443,-0.2537190743102173,2.5995589664368004,-0.09117605087284349,0.6017675204564823,1.06407470918364,4.3291217026971225,0.3017508900780304,3.5973077301556384 | 3,220 |
Glycerophospholipid metabolism | 14 | 20 | 2.417752 | 0.015617 | Q8NCC3,O15228,P43304,Q9BVG9,Q9HBU6,O14735,O95674,Q96N66,Q8NF37,Q6P1A2,Q9UG56,Q92604,Q99943,O15120 | Processes and pathways | KEGG Pathways | msigdb_kegg | 581,353,578,263,136,265,138,594,396,113,212,340,441,276 | 265,276,353,658,1096,138,865,2422,578,1740,113,2965,581,396,340,594,441,263,136,212 | 1.3528340672655668,1.3118301474062795,1.0779181486196767,0.544982758232892,0.15719497235672153,1.8920646818638314,0.330528729857457,-0.5380402143385864,0.6442470592213966,-0.19444171825613035,2.0380155210262614,-0.9813049356287264,0.6442470592213966,0.9808141312665962,1.1193918429266982,0.6300975384411448,0.8972068072481052,1.3664840566092424,1.9053732541087869,1.5295919290991515 | 3,220 |
Protein import into mitochondrial matrix | 7 | 9 | 2.409877 | 0.015958 | Q99595,O94826,O60830,O43615,Q15388,O96008,O14925 | Processes and pathways | GO Biological process | msigdb_gobp | 64,598,37,520,620,300,29 | 29,520,37,598,300,620,674,64,1343 | 3.361075633693647,0.7430072800978298,3.2106974716483787,0.6159377018946759,1.2433090578397443,0.6017675204564823,0.5307604103957996,2.663965486017274,0.011503046829603012 | 3,220 |
Mitochondrial fission | 8 | 15 | 2.406195 | 0.01612 | Q9NUQ9,O60313,Q8TB36,Q8NE86,O00203,Q9NX47,O94830,Q9UDX5 | Processes and pathways | GO Biological process | msigdb_gobp | 389,521,593,406,433,183,402,127 | 433,1529,521,402,1730,1545,406,593,694,911,1820,936,389,183,127 | 0.9111656785685303,-0.1058920750579502,0.7430072800978298,0.9669038074280564,-0.19444171825613035,-0.1058920750579502,0.9669038074280564,0.6300975384411448,0.5022841164890406,0.3017508900780304,-0.2240557615419202,0.28734545070934525,0.9947148236194842,1.6376330607839327,1.958526536843602 | 3,220 |
Mib complex | 7 | 11 | 2.395702 | 0.016589 | O75431,Q9Y512,Q9BUR5,Q13505,Q9NX63,Q5XKP0,Q6UXV4 | Localization | GO Cellular component | msigdb_gocc | 348,323,71,41,557,16,250 | 348,1736,41,602,889,16,250,71,809,557,323 | 1.0917521341398324,-0.19444171825613035,3.1099250993926355,0.6159377018946759,0.3161453056172049,3.7822378308851308,1.4073803914068117,2.5995589664368004,0.38795315862879387,0.6866340160886069,1.174558901603863 | 3,220 |
Pink1 prkn mediated mitophagy | 6 | 8 | 2.381916 | 0.017223 | O94826,Q8N4H5,P21796,Q8IWA4,O96008,Q9NS69 | Processes and pathways | Reactome Pathways | msigdb_reactome | 598,4,70,364,300,21 | 598,1201,300,70,620,364,4,21 | 0.6159377018946759,0.08449317262514162,1.2433090578397443,2.5995589664368004,0.6017675204564823,1.06407470918364,4.3291217026971225,3.5973077301556384 | 3,220 |
Scotoma | 6 | 15 | 2.376508 | 0.017477 | O75306,Q9H061,Q9H6K4,P03886,P00846,Q9Y287 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 483,6,7,103,115,391 | 1529,1799,521,483,1201,115,103,2440,2161,2882,766,2408,6,7,391 | -0.1058920750579502,-0.2240557615419202,0.7430072800978298,0.8132470889449575,0.08449317262514162,2.0247872950224237,2.090849287701112,-0.553133878075549,-0.4027859480941016,-0.873231681277683,0.43090764101721113,-0.5229597504510352,4.3291217026971225,4.3291217026971225,0.9947148236194842 | 3,220 |
Peripheral demyelination | 8 | 17 | 2.375195 | 0.01754 | O43681,P03886,Q8TB36,Q9NZJ7,P00846,Q9NR77,P50570,P07196 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 261,103,593,140,115,443,410,535 | 261,115,103,535,638,2419,886,1379,1571,410,2168,1541,593,1420,443,140,1131 | 1.3664840566092424,2.0247872950224237,2.090849287701112,0.7148409361035052,0.5733960056844266,-0.5380402143385864,0.3161453056172049,-0.01777473199075143,-0.1206201069740683,0.9529838262623884,-0.4027859480941016,-0.1058920750579502,0.6300975384411448,-0.03243127960906722,0.8972068072481052,1.8920646818638314,0.14267746792433023 | 3,220 |
Maintenance of protein location in cell | 9 | 20 | 2.372165 | 0.017684 | P24390,P30536,O43292,P52789,Q13438,Q9H4A6,O15258,Q9UH99,O43731 | Processes and pathways | GO Biological process | msigdb_gobp | 164,197,137,171,362,173,110,275,92 | 110,137,92,359,886,164,197,601,1990,171,569,2892,2680,907,362,1389,1271,2326,173,275 | 2.0380155210262614,1.8920646818638314,2.2092672490607383,1.06407470918364,0.3161453056172049,1.7451289416289844,1.570171930412102,0.6159377018946759,-0.313194785097642,1.704881209746608,0.6583862932184593,-0.8886275567160946,-0.6895783192988665,0.3017508900780304,1.06407470918364,-0.01777473199075143,0.055331969068424594,-0.47779711418441184,1.704881209746608,1.3255071355722057 | 3,220 |
Central scotoma | 6 | 12 | 2.37208 | 0.017688 | O75306,Q9H061,Q9H6K4,P03886,P00846,Q9Y287 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 483,6,7,103,115,391 | 1529,521,483,1201,115,103,2161,2882,766,6,7,391 | -0.1058920750579502,0.7430072800978298,0.8132470889449575,0.08449317262514162,2.0247872950224237,2.090849287701112,-0.4027859480941016,-0.873231681277683,0.43090764101721113,4.3291217026971225,4.3291217026971225,0.9947148236194842 | 3,220 |
Protein transmembrane transport | 17 | 28 | 2.367975 | 0.017886 | Q99442,Q99595,O94826,O60830,O43615,O95831,Q15629,O75298,O96008,Q9Y5Y5,P31751,Q9NS69,Q9Y584,O75381,O14925,Q07820,P49755 | Processes and pathways | GO Biological process | msigdb_gobp | 513,64,598,37,520,416,75,108,300,174,527,21,23,370,29,222,511 | 29,520,37,108,370,598,416,300,1987,527,511,771,1435,1144,1209,222,620,75,674,3173,748,513,64,1343,21,1022,23,174 | 3.361075633693647,0.7430072800978298,3.2106974716483787,2.0512358149832477,1.0224874166341895,0.6159377018946759,0.9390541618071563,1.2433090578397443,-0.313194785097642,0.7289291660118463,0.7711332727194923,0.4166002588713612,-0.04709964827475354,0.12814857045825676,0.08449317262514162,1.4889337304892023,0.6017675204564823,2.4831720044145342,0.5307604103957996,-1.9226522752457913,0.4452042862052327,0.7711332727194923,2.663965486017274,0.011503046829603012,3.5973077301556384,0.2151517460221033,3.5725469272262074,1.704881209746608 | 3,220 |
Underdeveloped supraorbital ridges | 9 | 14 | 2.353205 | 0.018612 | Q6NUK1,P56589,Q6PGP7,P16435,Q92968,Q9Y5Y5,P40855,Q08J23,O75381 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 290,331,523,269,748,174,587,404,370 | 370,269,1408,587,771,1705,331,987,2023,404,290,523,748,174 | 1.0224874166341895,1.3391751012056732,-0.03243127960906722,0.6300975384411448,0.4166002588713612,-0.1796530741697238,1.1331976156562682,0.24406266179274372,-0.3280950079380358,0.9669038074280564,1.2844490111299678,0.7430072800978298,0.4452042862052327,1.704881209746608 | 3,220 |
Proton transporting two sector atpase complex proton transporting domain | 6 | 11 | 2.34191 | 0.019185 | O75947,P24539,Q93050,P56385,O75964,P00846 | Localization | GO Cellular component | msigdb_gocc | 288,330,565,306,17,115 | 760,288,17,115,330,1808,1675,306,1480,565,596 | 0.43090764101721113,1.2844490111299678,3.7453603850636794,2.0247872950224237,1.1331976156562682,-0.2240557615419202,-0.164876629692285,1.2295774465746885,-0.07647199667296625,0.6725152692738572,0.6300975384411448 | 3,220 |
Mitochondria associated endoplasmic reticulum membrane | 7 | 10 | 2.33727 | 0.019425 | P51572,Q96N66,Q15388,O96008,P27824,Q9Y320,P56962 | Localization | GO Cellular component | msigdb_gocc | 485,594,620,300,236,216,214 | 1727,1094,300,236,485,214,620,594,653,216 | -0.19444171825613035,0.15719497235672153,1.2433090578397443,1.4346001455642394,0.8132470889449575,1.5160479135785023,0.6017675204564823,0.6300975384411448,0.5591946133780552,1.5160479135785023 | 3,220 |
Cristae formation | 6 | 9 | 2.333623 | 0.019615 | Q9Y512,Q9BUR5,Q9NX63,Q5XKP0,O95202,Q6UXV4 | Processes and pathways | GO Biological process | msigdb_gobp | 323,71,557,16,124,250 | 124,602,16,250,71,809,557,1281,323 | 1.9717947009390235,0.6159377018946759,3.7822378308851308,1.4073803914068117,2.5995589664368004,0.38795315862879387,0.6866340160886069,0.055331969068424594,1.174558901603863 | 3,220 |
Synaptic vesicle membrane | 9 | 14 | 2.327273 | 0.019951 | P0DP25,P61020,O76024,P20020,Q15907,O60499,O43760,O43752,P20339 | Localization | GO Cellular component | msigdb_gocc | 727,800,262,680,149,118,184,249,728 | 1529,249,184,118,262,885,727,680,728,1838,800,1441,149,1216 | -0.1058920750579502,1.4073803914068117,1.6241579565962334,2.0115511185478705,1.3664840566092424,0.3161453056172049,0.4594902255077705,0.5165275398650023,0.4594902255077705,-0.23888123943057013,0.38795315862879387,-0.04709964827475354,1.8253993507524382,0.08449317262514162 | 3,220 |
Signaling | 10 | 17 | 2.326529 | 0.01999 | Q7Z4V5,Q96PC5,Q07812,Q99627,O15173,Q5JRA6,P42166,Q9UHD1,O00264,Q07820 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 707,97,354,297,11,684,491,667,88,222 | 88,11,1767,491,701,1410,354,222,2261,684,707,955,2839,1916,97,297,667 | 2.2747847087222794,4.293019093243848,-0.20924260096857328,0.7992191364595662,0.4880301099656987,-0.03243127960906722,1.0779181486196767,1.4889337304892023,-0.447753880325114,0.5165275398650023,0.4880301099656987,0.27292895481255514,-0.8271293488640873,-0.2685693060796182,2.143557307496829,1.2570315066503508,0.544982758232892 | 3,220 |
Mitochondrial transmembrane transport | 31 | 55 | 2.325633 | 0.020038 | O95563,O75964,Q8NE86,Q96AQ8,P05141,O14925,P12235,O75947,Q9UJZ1,Q9H4I9,O60830,O95831,Q8WWC4,O96008,Q8IYU8,P56385,P23786,P12236,Q9BQT8,Q9Y619,Q99595,Q96ER9,P21796,P24539,Q9BSK2,Q9BPX6,P50416,Q9H2D1,P00846,Q6P4A7,O95202 | Processes and pathways | GO Biological process | msigdb_gobp | 129,17,406,282,403,29,158,288,422,38,37,416,172,300,175,306,182,185,313,188,64,325,70,330,210,342,213,99,115,378,124 | 29,520,2641,37,1351,1451,575,288,17,598,124,129,416,300,115,403,1403,1987,158,185,70,182,330,1836,985,1808,213,617,1675,306,703,620,1909,674,378,175,406,1882,172,282,325,457,64,342,313,210,99,38,752,678,1343,778,422,1281,188 | 3.361075633693647,0.7430072800978298,-0.674363810312437,3.2106974716483787,-0.003129968688779517,-0.06177987491864927,0.6442470592213966,1.2844490111299678,3.7453603850636794,0.6159377018946759,1.9717947009390235,1.9452503290298178,0.9390541618071563,1.2433090578397443,2.0247872950224237,0.9669038074280564,-0.03243127960906722,-0.313194785097642,1.7853014752695062,1.6241579565962334,2.5995589664368004,1.6376330607839327,1.1331976156562682,-0.23888123943057013,0.24406266179274372,-0.2240557615419202,1.5160479135785023,0.6017675204564823,-0.164876629692285,1.2295774465746885,0.4880301099656987,0.6017675204564823,-0.2685693060796182,0.5307604103957996,1.0086059102080356,1.6914484940680552,0.9669038074280564,-0.2537190743102173,1.704881209746608,1.3118301474062795,1.160781120599868,0.8692596729318535,2.663965486017274,1.1193918429266982,1.2020866418225167,1.5295919290991515,2.143557307496829,3.2106974716483787,0.4452042862052327,0.5307604103957996,0.011503046829603012,0.4166002588713612,0.9390541618071563,0.055331969068424594,1.6241579565962334 | 3,220 |
Very long chain fatty acid accumulation | 8 | 10 | 2.317379 | 0.020483 | Q5T8D3,P56589,Q9Y5Y5,Q92968,P40855,P33897,Q96AD5,O75381 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 675,331,174,748,587,426,566,370 | 370,426,587,771,1305,331,675,748,566,174 | 1.0224874166341895,0.9251147879781412,0.6300975384411448,0.4166002588713612,0.02612435090038817,1.1331976156562682,0.5307604103957996,0.4452042862052327,0.6725152692738572,1.704881209746608 | 3,220 |
Mitochondrial immune response to sarscov2 | 6 | 9 | 2.311863 | 0.020785 | O94826,Q99623,P35232,Q86UT6,Q7Z434,Q9Y276 | Processes and pathways | WikiPathways | msigdb_wp | 598,260,543,296,431,477 | 598,543,431,296,260,1104,1196,477,625 | 0.6159377018946759,0.7007425622241883,0.9251147879781412,1.270744816588314,1.3801250919931503,0.15719497235672153,0.09905645771621088,0.8412731718875827,0.6017675204564823 | 3,220 |
Ion channel | 7 | 11 | 2.309541 | 0.020914 | Q4KMQ2,Q96ER9,Q96S66,Q8NE86,Q9Y696,Q9UM00,Q9C0H2 | Functions | Protein Atlas Molecular function | protein_atlas_molecular_function | 545,325,653,406,218,316,606 | 1427,1113,545,406,325,653,655,606,916,316,218 | -0.04709964827475354,0.14267746792433023,0.7007425622241883,0.9669038074280564,1.160781120599868,0.5591946133780552,0.5591946133780552,0.6159377018946759,0.3017508900780304,1.2020866418225167,1.5160479135785023 | 3,220 |
Cns demyelination | 6 | 15 | 2.302418 | 0.021312 | Q9NZJ7,P51648,P40855,P33897,Q9H9P8,Q15067 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 140,44,587,426,408,537 | 638,426,587,1571,1433,44,2168,1212,833,537,1486,408,1225,140,2069 | 0.5733960056844266,0.9251147879781412,0.6300975384411448,-0.1206201069740683,-0.04709964827475354,3.059380306475877,-0.4027859480941016,0.08449317262514162,0.35926273373079604,0.7148409361035052,-0.07647199667296625,0.9669038074280564,0.08449317262514162,1.8920646818638314,-0.3430078305713249 | 3,220 |
Abnormal circulating fatty acid concentration | 8 | 23 | 2.299365 | 0.021484 | O75431,Q9P0S2,P56589,P40939,Q9Y5Y5,O75880,P23786,O75381 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 348,10,331,427,174,298,182,370 | 2641,370,348,1112,298,1404,1074,182,426,2136,587,427,1287,771,1305,1778,331,1515,1360,748,1196,10,174 | -0.674363810312437,1.0224874166341895,1.0917521341398324,0.14267746792433023,1.2433090578397443,-0.03243127960906722,0.1717011182043829,1.6376330607839327,0.9251147879781412,-0.387822311164995,0.6300975384411448,0.9251147879781412,0.04073397966432928,0.4166002588713612,0.02612435090038817,-0.20924260096857328,1.1331976156562682,-0.09117605087284349,-0.003129968688779517,0.4452042862052327,0.09905645771621088,4.3291217026971225,1.704881209746608 | 3,220 |
Glycerophospholipid biosynthesis | 24 | 38 | 2.288898 | 0.022085 | Q9NPH0,Q9BVG9,Q9HBU6,O14735,O95674,Q8NF37,O94830,O15120,Q9NQZ5,P40939,Q96AD5,Q99943,Q8NCC3,Q8N2A8,P43304,Q53H12,Q9UG56,Q92604,O15228,Q8WUK0,Q8IV08,Q6P1A2,Q9C0D9,Q9NUQ2 | Processes and pathways | Reactome Pathways | msigdb_reactome | 131,263,136,265,138,396,402,276,170,427,566,441,581,67,578,204,212,340,353,226,488,113,375,125 | 265,276,353,2359,402,138,865,1865,2422,427,578,1740,1261,1778,1507,204,113,2965,488,67,1365,581,396,226,340,566,594,892,441,263,677,375,136,712,131,170,125,212 | 1.3528340672655668,1.3118301474062795,1.0779181486196767,-0.5078924419127835,0.9669038074280564,1.8920646818638314,0.330528729857457,-0.2537190743102173,-0.5380402143385864,0.9251147879781412,0.6442470592213966,-0.19444171825613035,0.055331969068424594,-0.20924260096857328,-0.09117605087284349,1.5566539160615283,2.0380155210262614,-0.9813049356287264,0.8132470889449575,2.62534308033295,-0.003129968688779517,0.6442470592213966,0.9808141312665962,1.4753635194517039,1.1193918429266982,0.6725152692738572,0.6300975384411448,0.3161453056172049,0.8972068072481052,1.3664840566092424,0.5307604103957996,1.0224874166341895,1.9053732541087869,0.4880301099656987,1.9452503290298178,1.7183055093529294,1.9717947009390235,1.5295919290991515 | 3,220 |
Carbohydrate derivative transmembrane transporter activity | 8 | 10 | 2.287641 | 0.022158 | L0R6Q1,Q6NUK1,Q8TB61,P05141,P12236,P12235,O43808,O00400 | Functions | GO Molecular function | msigdb_gomf | 102,290,104,403,185,158,317,62 | 102,62,317,403,158,185,426,3175,290,104 | 2.090849287701112,2.6768253453241613,1.1883274006382527,0.9669038074280564,1.7853014752695062,1.6241579565962334,0.9251147879781412,-1.9556055796511111,1.2844490111299678,2.090849287701112 | 3,220 |
Peroxisome organization | 11 | 16 | 2.281366 | 0.022527 | O75192,P56589,O14734,Q7Z434,P50542,Q92968,Q96HA9,P40855,P33897,Q9Y5Y5,O75381 | Processes and pathways | GO Biological process | msigdb_gobp | 96,331,796,431,771,748,109,587,426,174,370 | 1529,796,96,370,827,1008,426,587,771,331,431,748,109,936,2516,174 | -0.1058920750579502,0.38795315862879387,2.1567147995211386,1.0224874166341895,0.35926273373079604,0.2151517460221033,0.9251147879781412,0.6300975384411448,0.4166002588713612,1.1331976156562682,0.9251147879781412,0.4452042862052327,2.0512358149832477,0.28734545070934525,-0.5833609844142108,1.704881209746608 | 3,220 |
Purine nucleotide transport | 8 | 10 | 2.26192 | 0.023702 | Q6NUK1,Q8TB61,P05141,P12236,P12235,O43808,O00400,Q08722 | Processes and pathways | GO Biological process | msigdb_gobp | 290,104,403,185,158,317,62,255 | 62,317,403,158,185,426,3175,255,290,104 | 2.6768253453241613,1.1883274006382527,0.9669038074280564,1.7853014752695062,1.6241579565962334,0.9251147879781412,-1.9556055796511111,1.3937571960734862,1.2844490111299678,2.090849287701112 | 3,220 |
Protein insertion into membrane | 15 | 33 | 2.239993 | 0.025091 | Q8N4V1,Q9Y512,O43681,Q15070,Q8N8Q8,Q8WWC4,Q9NPA0,Q53H12,Q15629,Q9Y5J6,Q9Y5J9,Q9NS69,Q96A33,Q9Y584,P62072 | Processes and pathways | GO Biological process | msigdb_gobp | 161,323,261,42,139,172,142,204,75,346,181,21,53,23,26 | 670,1800,261,1163,598,1325,2935,2135,579,1209,26,354,2322,42,75,204,1013,998,3196,161,1062,139,172,53,142,21,740,1252,477,323,23,346,181 | 0.5307604103957996,-0.2240557615419202,1.3664840566092424,0.11360824532721736,0.6159377018946759,0.011503046829603012,-0.9503545811838279,-0.387822311164995,0.6442470592213966,0.08449317262514162,3.448371427949981,1.0779181486196767,-0.47779711418441184,3.0972988744230174,2.4831720044145342,1.5566539160615283,0.2151517460221033,0.22961279842123378,-2.9289291132688615,1.7719189526049448,0.1861959397352981,1.8920646818638314,1.704881209746608,2.7922458252893323,1.8654231014435778,3.5973077301556384,0.4594902255077705,0.06991835486739327,0.8412731718875827,1.174558901603863,3.5725469272262074,1.1055766906461557,1.6510996458924831 | 3,220 |
Decreased activity of mitochondrial complex iv | 6 | 18 | 2.229067 | 0.025809 | Q9P0S2,Q70HW3,P13073,Q9Y584,Q9Y2R0,P20674 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 10,47,112,23,122,349 | 994,2850,112,349,1571,948,2758,1458,1608,3063,47,858,2567,877,10,122,414,23 | 0.22961279842123378,-0.842482628027553,2.0380155210262614,1.0917521341398324,-0.1206201069740683,0.27292895481255514,-0.7505734286242784,-0.06177987491864927,-0.13536018457472698,-1.1682498880917347,2.9706691886854455,0.344901195162577,-0.6136414307633394,0.330528729857457,4.3291217026971225,1.9850548401175079,0.9529838262623884,3.5725469272262074 | 3,220 |
Inorganic anion transmembrane transporter activity | 6 | 18 | 2.225141 | 0.026072 | Q9Y277,P21796,P45880,Q9Y696,Q9NW15,Q9UBX3 | Functions | GO Molecular function | msigdb_gomf | 66,70,50,218,151,61 | 1427,261,1113,70,50,2081,2167,1208,869,545,3186,653,606,151,61,66,218,977 | -0.04709964827475354,1.3664840566092424,0.14267746792433023,2.5995589664368004,2.907101064760008,-0.35793329427295245,-0.4027859480941016,0.08449317262514162,0.330528729857457,0.7007425622241883,-2.272475202383778,0.5591946133780552,0.6159377018946759,1.8253993507524382,2.689678092109702,2.6382243688422604,1.5160479135785023,0.25850136951980746 | 3,220 |
Regulation of amyloid precursor protein catabolic process | 6 | 15 | 2.223358 | 0.026192 | O75298,O95197,Q9NQC3,P62942,Q16799,P49755 | Processes and pathways | GO Biological process | msigdb_gobp | 108,15,117,503,94,511 | 108,15,1300,2077,511,1478,503,3131,1965,909,1213,94,547,913,117 | 2.0512358149832477,3.868076986161342,0.02612435090038817,-0.35793329427295245,0.7711332727194923,-0.07647199667296625,0.7851812068774792,-1.468787945000136,-0.29830712100880136,0.3017508900780304,0.08449317262514162,2.2092672490607383,0.7007425622241883,0.3017508900780304,2.0247872950224237 | 3,220 |
acyltransferase | 12 | 21 | 2.223124 | 0.026207 | Q8NCC3,O15228,Q8NF37,Q86SQ9,P35610,Q92604,Q99943,O15120,P23786,P50416,P14324,Q9NUQ2 | Functions | Panther Protein class | panther_protein_class | 581,353,396,367,271,340,441,276,182,213,278,125 | 276,353,278,182,1699,271,2716,1409,639,213,1538,1778,2965,367,581,396,340,2176,441,1294,125 | 1.3118301474062795,1.0779181486196767,1.3118301474062795,1.6376330607839327,-0.1796530741697238,1.3255071355722057,-0.7200483638187551,-0.03243127960906722,0.5733960056844266,1.5160479135785023,-0.1058920750579502,-0.20924260096857328,-0.9813049356287264,1.0502217908149432,0.6442470592213966,0.9808141312665962,1.1193918429266982,-0.4027859480941016,0.8972068072481052,0.04073397966432928,1.9717947009390235 | 3,220 |
Acylglycerol o acyltransferase activity | 8 | 10 | 2.201117 | 0.027728 | Q8NCC3,Q8NF37,Q6P1A2,Q96AD5,Q92604,Q99943,O15120,Q9NUQ2 | Functions | GO Molecular function | msigdb_gomf | 581,396,113,566,340,441,276,125 | 276,113,2965,581,396,340,566,594,441,125 | 1.3118301474062795,2.0380155210262614,-0.9813049356287264,0.6442470592213966,0.9808141312665962,1.1193918429266982,0.6725152692738572,0.6300975384411448,0.8972068072481052,1.9717947009390235 | 3,220 |
Intracellular protein transmembrane transport | 14 | 24 | 2.193871 | 0.028245 | Q99442,Q99595,O94826,O60830,O43615,O95831,Q15388,Q15629,O75298,O96008,Q9Y5Y5,P31751,O75381,O14925 | Processes and pathways | GO Biological process | msigdb_gobp | 513,64,598,37,520,416,620,75,108,300,174,527,370,29 | 29,520,37,108,370,598,416,300,1987,527,771,1435,1144,1209,620,75,674,3173,748,513,64,1343,1022,174 | 3.361075633693647,0.7430072800978298,3.2106974716483787,2.0512358149832477,1.0224874166341895,0.6159377018946759,0.9390541618071563,1.2433090578397443,-0.313194785097642,0.7289291660118463,0.4166002588713612,-0.04709964827475354,0.12814857045825676,0.08449317262514162,0.6017675204564823,2.4831720044145342,0.5307604103957996,-1.9226522752457913,0.4452042862052327,0.7711332727194923,2.663965486017274,0.011503046829603012,0.2151517460221033,1.704881209746608 | 3,220 |
Fatty acid betaoxidation | 7 | 21 | 2.18452 | 0.028924 | P43304,P40939,Q96AD5,P35610,P23786,Q9UKU0,P50416 | Processes and pathways | WikiPathways | msigdb_wp | 578,427,566,271,182,25,213 | 2641,1094,1697,1404,1074,182,1699,1503,585,271,427,1141,578,1287,213,1778,1054,1515,1420,566,25 | -0.674363810312437,0.15719497235672153,-0.1796530741697238,-0.03243127960906722,0.1717011182043829,1.6376330607839327,-0.1796530741697238,-0.09117605087284349,0.6300975384411448,1.3255071355722057,0.9251147879781412,0.12814857045825676,0.6442470592213966,0.04073397966432928,1.5160479135785023,-0.20924260096857328,0.1861959397352981,-0.09117605087284349,-0.03243127960906722,0.6725152692738572,3.4981163078685293 | 3,220 |
Peroxisomes | 9 | 17 | 2.182872 | 0.029045 | O15254,Q5T8D3,O00116,P56589,Q92968,P40855,O75381,Q15067,O43808 | Localization | Protein Atlas Subcellular | protein_atlas_subcellular_location_all | 192,675,697,331,748,587,370,537,317 | 697,192,317,370,1564,1139,827,1008,587,1305,331,537,675,1655,748,1067,1197 | 0.4880301099656987,1.5971821074339623,1.1883274006382527,1.0224874166341895,-0.1206201069740683,0.12814857045825676,0.35926273373079604,0.2151517460221033,0.6300975384411448,0.02612435090038817,1.1331976156562682,0.7148409361035052,0.5307604103957996,-0.15011234602282414,0.4452042862052327,0.1861959397352981,0.09905645771621088 | 3,220 |
Abnormal circulating long chain fatty acid concentration | 7 | 8 | 2.175478 | 0.029594 | P56589,Q9Y5Y5,Q92968,P40855,P33897,P23786,O75381 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 331,174,748,587,426,182,370 | 370,182,426,587,771,331,748,174 | 1.0224874166341895,1.6376330607839327,0.9251147879781412,0.6300975384411448,0.4166002588713612,1.1331976156562682,0.4452042862052327,1.704881209746608 | 3,220 |
Diabetes mellitus | 7 | 13 | 2.169891 | 0.030015 | O76024,P03886,P40763,P31751,Q8N5K1,O15120,Q5VV42 | Drugs and Diseases | Protein Atlas Disease involvement | protein_atlas_disease_involvement | 262,103,553,527,564,276,91 | 276,2157,262,103,648,527,553,1478,850,2112,91,564,1069 | 1.3118301474062795,-0.4027859480941016,1.3664840566092424,2.090849287701112,0.5591946133780552,0.7289291660118463,0.6866340160886069,-0.07647199667296625,0.344901195162577,-0.37287144055437577,2.248600683439519,0.6725152692738572,0.1861959397352981 | 3,220 |
Snare complex | 9 | 20 | 2.168211 | 0.030143 | O14653,O95249,O75396,O60499,Q9NZ43,Q12846,P56962,O43752,Q9P2W9 | Localization | GO Cellular component | msigdb_gocc | 225,73,452,118,314,372,214,249,31 | 2593,225,1109,2187,249,118,452,73,1429,772,1236,214,372,562,672,1216,3037,314,31,1497 | -0.6439755827313389,1.4753635194517039,0.14267746792433023,-0.4177623935728443,1.4073803914068117,2.0115511185478705,0.8692596729318535,2.52203320891506,-0.04709964827475354,0.4166002588713612,0.06991835486739327,1.5160479135785023,1.0224874166341895,0.6725152692738572,0.5307604103957996,0.08449317262514162,-1.1213111905822806,1.2020866418225167,3.3485794389162113,-0.07647199667296625 | 3,220 |
Inorganic anion transport | 9 | 24 | 2.158964 | 0.030853 | P54105,Q9UHG3,Q9Y277,P30536,P21796,P45880,Q9Y696,Q9NW15,Q9UBX3 | Processes and pathways | GO Biological process | msigdb_gobp | 160,224,66,197,70,50,218,151,61 | 1427,261,484,1113,70,197,50,2081,2167,160,1208,703,869,545,3186,653,606,807,151,61,224,66,218,977 | -0.04709964827475354,1.3664840566092424,0.8132470889449575,0.14267746792433023,2.5995589664368004,1.570171930412102,2.907101064760008,-0.35793329427295245,-0.4027859480941016,1.7719189526049448,0.08449317262514162,0.4880301099656987,0.330528729857457,0.7007425622241883,-2.272475202383778,0.5591946133780552,0.6159377018946759,0.38795315862879387,1.8253993507524382,2.689678092109702,1.4889337304892023,2.6382243688422604,1.5160479135785023,0.25850136951980746 | 3,220 |
Fad binding | 8 | 11 | 2.152303 | 0.031374 | O15254,O95831,Q14534,O00116,Q15392,Q8NB78,Q15067,P00387 | Functions | GO Molecular function | msigdb_gomf | 192,416,229,697,495,723,537,284 | 697,192,416,284,229,537,495,723,1040,1023,811 | 0.4880301099656987,1.5971821074339623,0.9390541618071563,1.298144113646831,1.4617845329488237,0.7148409361035052,0.7992191364595662,0.473765489840932,0.20067947103783892,0.2151517460221033,0.38795315862879387 | 3,220 |
Endoplasmic reticulum golgi intermediate compartment membrane | 17 | 30 | 2.147366 | 0.031764 | O14653,P24390,P51572,Q03518,O75396,Q5BJH7,Q10472,Q8N511,Q969X5,Q9Y3A6,P61019,Q9Y282,P56962,Q96RQ1,Q9H0U4,O95070,P49755 | Localization | GO Cellular component | msigdb_gocc | 225,164,485,228,452,76,238,80,341,344,494,56,214,187,442,189,511 | 225,1093,2187,452,189,164,2980,511,485,2733,214,494,228,1904,928,238,690,672,1239,1707,2881,76,80,341,187,749,442,56,344,532 | 1.4753635194517039,0.15719497235672153,-0.4177623935728443,0.8692596729318535,1.6106743124643152,1.7451289416289844,-1.0123137479236077,0.7711332727194923,0.8132470889449575,-0.7353039946740639,1.5160479135785023,0.7992191364595662,1.4617845329488237,-0.2685693060796182,0.28734545070934525,1.4346001455642394,0.5022841164890406,0.5307604103957996,0.06991835486739327,-0.1796530741697238,-0.873231681277683,2.431254128827567,2.4052507839119524,1.1193918429266982,1.6241579565962334,0.4452042862052327,0.8972068072481052,2.753835667498494,1.1193918429266982,0.7289291660118463 | 3,220 |
Amyloid precursor protein catabolic process | 7 | 17 | 2.146991 | 0.031794 | Q15392,O75298,O95197,Q9NQC3,P62942,Q16799,P49755 | Processes and pathways | GO Biological process | msigdb_gobp | 495,108,15,117,503,94,511 | 108,15,1300,2077,511,1478,503,3131,1965,909,1213,495,94,856,547,913,117 | 2.0512358149832477,3.868076986161342,0.02612435090038817,-0.35793329427295245,0.7711332727194923,-0.07647199667296625,0.7851812068774792,-1.468787945000136,-0.29830712100880136,0.3017508900780304,0.08449317262514162,0.7992191364595662,2.2092672490607383,0.344901195162577,0.7007425622241883,0.3017508900780304,2.0247872950224237 | 3,220 |
Cation channel activity | 8 | 22 | 2.141747 | 0.032214 | O75947,Q96ER9,P24539,O75964,P56385,P00846,Q9NW15,Q9UM00 | Functions | GO Molecular function | msigdb_gomf | 288,325,330,17,306,115,151,316 | 288,17,115,1403,2159,2491,330,1836,985,1080,1808,1675,306,1209,545,406,2684,325,916,151,2462,316 | 1.2844490111299678,3.7453603850636794,2.0247872950224237,-0.03243127960906722,-0.4027859480941016,-0.5833609844142108,1.1331976156562682,-0.23888123943057013,0.24406266179274372,0.1717011182043829,-0.2240557615419202,-0.164876629692285,1.2295774465746885,0.08449317262514162,0.7007425622241883,0.9669038074280564,-0.6895783192988665,1.160781120599868,0.3017508900780304,1.8253993507524382,-0.553133878075549,1.2020866418225167 | 3,220 |
Amino acid transmembrane transport | 9 | 15 | 2.139314 | 0.03241 | Q9H9B4,O75746,Q96NB2,P30825,O75915,Q9H936,O60831,Q15041,Q9Y619 | Processes and pathways | GO Biological process | msigdb_gobp | 678,575,457,383,393,752,200,244,188 | 200,575,393,2361,1631,383,244,2202,457,1754,1043,752,678,778,188 | 1.5566539160615283,0.6442470592213966,0.9808141312665962,-0.5078924419127835,-0.15011234602282414,0.9947148236194842,1.420994700450676,-0.4177623935728443,0.8692596729318535,-0.19444171825613035,0.20067947103783892,0.4452042862052327,0.5307604103957996,0.4166002588713612,1.6241579565962334 | 3,220 |
Spastic paraparesis | 6 | 23 | 2.13537 | 0.032731 | Q9H6K4,P21912,Q9Y5Y5,Q5XKP0,Q9C0D9,Q9Y619 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 7,266,174,16,375,188 | 760,1164,2693,1804,1233,266,1700,426,2472,1542,871,2054,16,854,1654,1655,375,7,2153,1349,1281,174,188 | 0.43090764101721113,0.11360824532721736,-0.7048064879620904,-0.2240557615419202,0.06991835486739327,1.3528340672655668,-0.1796530741697238,0.9251147879781412,-0.5682407864248026,-0.1058920750579502,0.330528729857457,-0.3430078305713249,3.7822378308851308,0.344901195162577,-0.15011234602282414,-0.15011234602282414,1.0224874166341895,4.3291217026971225,-0.387822311164995,0.011503046829603012,0.055331969068424594,1.704881209746608,1.6241579565962334 | 3,220 |
Protein targeting to mitochondrion | 26 | 48 | 2.133936 | 0.032848 | Q8N4H5,O43615,Q9NS69,Q9Y584,Q99797,P62072,O14925,Q3ZCQ8,O60830,O95831,P55786,O96008,O00165,Q9Y5J9,Q99595,Q9Y512,P30536,Q53H12,Q8TB36,Q9H300,Q9Y371,Q9Y5J6,O94826,P51572,Q15388,Q10713 | Processes and pathways | GO Biological process | msigdb_gobp | 4,520,21,23,540,26,29,674,37,416,428,300,552,181,64,323,197,204,593,333,217,346,598,485,620,361 | 552,670,29,918,520,37,1451,598,1201,2767,1803,416,300,1325,1987,1865,197,2135,1478,485,428,26,831,361,620,1648,674,204,1650,2741,4,593,64,540,936,937,333,1343,21,1252,1371,1424,217,1922,323,23,346,181 | 0.6866340160886069,0.5307604103957996,3.361075633693647,0.28734545070934525,0.7430072800978298,3.2106974716483787,-0.06177987491864927,0.6159377018946759,0.08449317262514162,-0.7658567140592568,-0.2240557615419202,0.9390541618071563,1.2433090578397443,0.011503046829603012,-0.313194785097642,-0.2537190743102173,1.570171930412102,-0.387822311164995,-0.07647199667296625,0.8132470889449575,0.9251147879781412,3.448371427949981,0.35926273373079604,1.06407470918364,0.6017675204564823,-0.15011234602282414,0.5307604103957996,1.5566539160615283,-0.15011234602282414,-0.7353039946740639,4.3291217026971225,0.6300975384411448,2.663965486017274,0.7148409361035052,0.28734545070934525,0.28734545070934525,1.1331976156562682,0.011503046829603012,3.5973077301556384,0.06991835486739327,-0.003129968688779517,-0.03243127960906722,1.5160479135785023,-0.2685693060796182,1.174558901603863,3.5725469272262074,1.1055766906461557,1.6510996458924831 | 3,220 |
Phosphatidylglycerol metabolic process | 8 | 11 | 2.12765 | 0.033366 | Q8NCC3,Q8WUK0,Q9UJZ1,Q99623,O95674,Q8NF37,P40939,Q92604 | Processes and pathways | GO Biological process | msigdb_gobp | 581,226,422,260,138,396,427,340 | 138,427,2732,581,396,226,340,1103,260,712,422 | 1.8920646818638314,0.9251147879781412,-0.7353039946740639,0.6442470592213966,0.9808141312665962,1.4753635194517039,1.1193918429266982,0.15719497235672153,1.3801250919931503,0.4880301099656987,0.9390541618071563 | 3,220 |
Ragged red muscle fibers | 8 | 20 | 2.124498 | 0.033628 | Q9H2D1,O95831,P03886,Q70HW3,P00846,Q9Y276,P12235,O75340 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 99,416,103,47,115,477,158,347 | 347,1112,416,1598,115,103,158,1700,1458,1509,3063,47,496,2265,2455,1549,99,975,2796,477 | 1.0917521341398324,0.14267746792433023,0.9390541618071563,-0.13536018457472698,2.0247872950224237,2.090849287701112,1.7853014752695062,-0.1796530741697238,-0.06177987491864927,-0.09117605087284349,-1.1682498880917347,2.9706691886854455,0.7992191364595662,-0.447753880325114,-0.553133878075549,-0.1058920750579502,2.143557307496829,0.25850136951980746,-0.7811538996650151,0.8412731718875827 | 3,220 |
Purine nucleotide transmembrane transporter activity | 7 | 9 | 2.120915 | 0.033929 | Q6NUK1,Q8TB61,P05141,P12236,P12235,O43808,O00400 | Functions | GO Molecular function | msigdb_gomf | 290,104,403,185,158,317,62 | 62,317,403,158,185,426,3175,290,104 | 2.6768253453241613,1.1883274006382527,0.9669038074280564,1.7853014752695062,1.6241579565962334,0.9251147879781412,-1.9556055796511111,1.2844490111299678,2.090849287701112 | 3,220 |
Mitochondrial fusion | 8 | 16 | 2.119248 | 0.034069 | Q07812,Q8N2A8,Q9UJZ1,O60313,Q8IWA4,Q9NX63,Q9H300,Q9Y6C9 | Processes and pathways | GO Biological process | msigdb_gobp | 354,67,422,521,364,557,333,377 | 521,1201,3040,354,2741,364,67,1365,593,1245,936,333,557,422,1281,377 | 0.7430072800978298,0.08449317262514162,-1.1369422393917046,1.0779181486196767,-0.7353039946740639,1.06407470918364,2.62534308033295,-0.003129968688779517,0.6300975384411448,0.06991835486739327,0.28734545070934525,1.1331976156562682,0.6866340160886069,0.9390541618071563,0.055331969068424594,1.0224874166341895 | 3,220 |
Impaired vibration sensation in the lower limbs | 6 | 18 | 2.118352 | 0.034145 | O75298,P33897,Q9BRK0,P00846,Q9NR77,O00400 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 108,426,145,115,443,62 | 62,2304,1253,108,525,979,115,1987,426,731,1605,2195,802,1547,1655,145,1591,443 | 2.6768253453241613,-0.47779711418441184,0.055331969068424594,2.0512358149832477,0.7289291660118463,0.24406266179274372,2.0247872950224237,-0.313194785097642,0.9251147879781412,0.4594902255077705,-0.13536018457472698,-0.4177623935728443,0.38795315862879387,-0.1058920750579502,-0.15011234602282414,1.8520900546502441,-0.1206201069740683,0.8972068072481052 | 3,220 |
Peroxisomal lipid metabolism | 8 | 14 | 2.118032 | 0.034172 | Q5T8D3,O15254,O14734,P51648,P33897,O14975,Q15067,O43808 | Processes and pathways | Reactome Pathways | msigdb_reactome | 675,192,796,44,426,460,537,317 | 796,460,192,317,1564,1139,827,426,44,1305,537,675,1067,2516 | 0.38795315862879387,0.8552713566510017,1.5971821074339623,1.1883274006382527,-0.1206201069740683,0.12814857045825676,0.35926273373079604,0.9251147879781412,3.059380306475877,0.02612435090038817,0.7148409361035052,0.5307604103957996,0.1861959397352981,-0.5833609844142108 | 3,220 |
Positive regulation of response to endoplasmic reticulum stress | 6 | 8 | 2.117434 | 0.034223 | Q07812,P51572,P57088,Q4ZIN3,Q9UHD9,P46379 | Processes and pathways | GO Biological process | msigdb_gobp | 354,485,105,267,715,579 | 1163,761,579,485,105,354,267,715 | 0.11360824532721736,0.43090764101721113,0.6442470592213966,0.8132470889449575,2.0644481952430347,1.0779181486196767,1.3528340672655668,0.4880301099656987 | 3,220 |
Transport of vitamins nucleosides and related molecules | 6 | 7 | 2.107814 | 0.035047 | Q8TB61,P36404,P05141,O00400,P12236,P12235 | Processes and pathways | Reactome Pathways | msigdb_reactome | 104,601,403,62,185,158 | 62,403,158,185,601,735,104 | 2.6768253453241613,0.9669038074280564,1.7853014752695062,1.6241579565962334,0.6159377018946759,0.4594902255077705,2.090849287701112 | 3,220 |
Microbody membrane | 21 | 35 | 2.102514 | 0.035508 | Q9UKU0,Q15067,Q5T8D3,Q7Z434,P51648,Q9Y5Y5,P33897,Q9NR77,Q9NP80,O43808,P56589,O00116,Q8TB36,P40855,P33121,O14975,O75192,O15228,Q96HA9,Q92968,O75381 | Localization | GO Cellular component | msigdb_gocc | 25,537,675,431,44,174,426,443,712,317,331,697,593,587,585,460,96,353,109,748,370 | 697,460,353,317,1094,96,370,1697,922,1892,1008,585,426,1408,947,587,771,44,1305,331,537,675,954,431,875,593,1655,748,109,1946,1067,712,443,25,174 | 0.4880301099656987,0.8552713566510017,1.0779181486196767,1.1883274006382527,0.15719497235672153,2.1567147995211386,1.0224874166341895,-0.1796530741697238,0.28734545070934525,-0.2685693060796182,0.2151517460221033,0.6300975384411448,0.9251147879781412,-0.03243127960906722,0.27292895481255514,0.6300975384411448,0.4166002588713612,3.059380306475877,0.02612435090038817,1.1331976156562682,0.7148409361035052,0.5307604103957996,0.27292895481255514,0.9251147879781412,0.330528729857457,0.6300975384411448,-0.15011234602282414,0.4452042862052327,2.0512358149832477,-0.28343197486238475,0.1861959397352981,0.4880301099656987,0.8972068072481052,3.4981163078685293,1.704881209746608 | 3,220 |
Steroid binding | 7 | 21 | 2.102305 | 0.035527 | P30536,P21796,O15173,P38435,P45880,O95772,O00264 | Functions | GO Molecular function | msigdb_gomf | 197,70,11,270,50,85,88 | 88,1003,11,3133,979,85,1233,526,2491,70,1634,827,197,271,270,50,3176,1875,1821,2237,677 | 2.2747847087222794,0.2151517460221033,4.293019093243848,-1.4847663908172626,0.24406266179274372,2.3531546237426215,0.06991835486739327,0.7289291660118463,-0.5833609844142108,2.5995589664368004,-0.15011234602282414,0.35926273373079604,1.570171930412102,1.3255071355722057,1.3391751012056732,2.907101064760008,-1.9886334261219616,-0.2537190743102173,-0.2240557615419202,-0.4327516900762261,0.5307604103957996 | 3,220 |
Proton transporting two sector atpase complex | 7 | 24 | 2.101901 | 0.035562 | O75947,Q8N511,O75964,P56385,P56378,P00846,Q96IX5 | Localization | GO Cellular component | msigdb_gocc | 288,80,17,306,237,115,223 | 760,288,17,115,1403,903,2851,330,1836,985,904,1080,1808,1675,237,306,1480,1707,80,565,223,2212,596,1526 | 0.43090764101721113,1.2844490111299678,3.7453603850636794,2.0247872950224237,-0.03243127960906722,0.3017508900780304,-0.842482628027553,1.1331976156562682,-0.23888123943057013,0.24406266179274372,0.3017508900780304,0.1717011182043829,-0.2240557615419202,-0.164876629692285,1.4346001455642394,1.2295774465746885,-0.07647199667296625,-0.1796530741697238,2.4052507839119524,0.6725152692738572,1.4889337304892023,-0.4177623935728443,0.6300975384411448,-0.09117605087284349 | 3,220 |
Positive regulation of mitochondrion organization | 8 | 26 | 2.099759 | 0.03575 | Q07812,Q8N2A8,P21796,Q8NE86,Q96A26,Q9NX47,P05141,P12235 | Processes and pathways | GO Biological process | msigdb_gobp | 354,67,70,406,20,183,403,158 | 1529,670,918,402,1402,403,1730,158,70,946,1733,2935,1739,1478,850,354,67,406,20,911,1820,2326,936,183,1424,1922 | -0.1058920750579502,0.5307604103957996,0.28734545070934525,0.9669038074280564,-0.03243127960906722,0.9669038074280564,-0.19444171825613035,1.7853014752695062,2.5995589664368004,0.27292895481255514,-0.19444171825613035,-0.9503545811838279,-0.19444171825613035,-0.07647199667296625,0.344901195162577,1.0779181486196767,2.62534308033295,0.9669038074280564,3.5973077301556384,0.3017508900780304,-0.2240557615419202,-0.47779711418441184,0.28734545070934525,1.6376330607839327,-0.03243127960906722,-0.2685693060796182 | 3,220 |
Mitochondrial membrane organization | 29 | 53 | 2.095197 | 0.036153 | O60313,Q8N8Q8,Q5XKP0,Q9NS69,Q9Y584,P05141,P62072,P12235,Q13505,Q15070,Q9NX63,P52789,Q8WWC4,P45880,Q9Y5J9,O00203,Q9Y512,Q9H3K2,Q9BUR5,Q53H12,Q8IXI1,Q9Y5J6,Q9Y276,O75431,O94826,Q07812,Q8IWA4,O95202,Q6UXV4 | Processes and pathways | GO Biological process | msigdb_gobp | 521,139,16,21,23,403,26,158,41,42,557,171,172,50,181,433,323,69,71,204,591,346,477,348,598,354,364,124,250 | 433,670,521,348,598,1201,124,1402,403,1325,2753,727,158,1006,1733,2935,2135,1736,2716,50,2138,1478,850,771,171,26,354,41,42,602,674,204,889,16,250,364,591,1585,139,172,71,69,21,809,557,1252,1424,477,1281,323,23,346,181 | 0.9111656785685303,0.5307604103957996,0.7430072800978298,1.0917521341398324,0.6159377018946759,0.08449317262514162,1.9717947009390235,-0.03243127960906722,0.9669038074280564,0.011503046829603012,-0.7505734286242784,0.4594902255077705,1.7853014752695062,0.2151517460221033,-0.19444171825613035,-0.9503545811838279,-0.387822311164995,-0.19444171825613035,-0.7200483638187551,2.907101064760008,-0.387822311164995,-0.07647199667296625,0.344901195162577,0.4166002588713612,1.704881209746608,3.448371427949981,1.0779181486196767,3.1099250993926355,3.0972988744230174,0.6159377018946759,0.5307604103957996,1.5566539160615283,0.3161453056172049,3.7822378308851308,1.4073803914068117,1.06407470918364,0.6300975384411448,-0.1206201069740683,1.8920646818638314,1.704881209746608,2.5995589664368004,2.62534308033295,3.5973077301556384,0.38795315862879387,0.6866340160886069,0.06991835486739327,-0.03243127960906722,0.8412731718875827,0.055331969068424594,1.174558901603863,3.5725469272262074,1.1055766906461557,1.6510996458924831 | 3,220 |
Amino acid transport | 11 | 20 | 2.07986 | 0.037538 | Q9H9B4,O75746,Q96NB2,P30825,O75915,Q9H936,O60831,Q15041,Q96H78,Q6P4A7,Q9Y619 | Processes and pathways | GO Biological process | msigdb_gobp | 678,575,457,383,393,752,200,244,87,378,188 | 1161,200,575,393,2361,1631,383,1208,244,950,2202,378,87,457,1754,1043,752,678,778,188 | 0.11360824532721736,1.5566539160615283,0.6442470592213966,0.9808141312665962,-0.5078924419127835,-0.15011234602282414,0.9947148236194842,0.08449317262514162,1.420994700450676,0.27292895481255514,-0.4177623935728443,1.0086059102080356,2.3140036938827615,0.8692596729318535,-0.19444171825613035,0.20067947103783892,0.4452042862052327,0.5307604103957996,0.4166002588713612,1.6241579565962334 | 3,220 |
Intracellular calcium-sensing protein | 7 | 17 | 2.077123 | 0.03779 | Q14257,P41208,P80303,Q8IYU8,Q02818,Q9BPX6,P14649 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 165,202,12,175,79,342,119 | 699,727,119,3052,202,445,2082,12,79,165,2500,1680,2607,175,2453,342,2484 | 0.4880301099656987,0.4594902255077705,2.0115511185478705,-1.1525884528897288,1.5566539160615283,0.8832381475623974,-0.35793329427295245,4.2327374623763125,2.4052507839119524,1.7317214132284093,-0.5833609844142108,-0.164876629692285,-0.6439755827313389,1.6914484940680552,-0.553133878075549,1.1193918429266982,-0.5682407864248026 | 3,220 |
Calmodulin | 7 | 17 | 2.077123 | 0.03779 | Q14257,P41208,P80303,Q8IYU8,Q02818,Q9BPX6,P14649 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 165,202,12,175,79,342,119 | 699,727,119,3052,202,445,2082,12,79,165,2500,1680,2607,175,2453,342,2484 | 0.4880301099656987,0.4594902255077705,2.0115511185478705,-1.1525884528897288,1.5566539160615283,0.8832381475623974,-0.35793329427295245,4.2327374623763125,2.4052507839119524,1.7317214132284093,-0.5833609844142108,-0.164876629692285,-0.6439755827313389,1.6914484940680552,-0.553133878075549,1.1193918429266982,-0.5682407864248026 | 3,220 |
Membrane organization | 100 | 241 | 2.072239 | 0.038243 | O60313,Q5XKP0,P31751,Q9NS69,Q9BTV4,Q9Y584,P62072,Q9P2W9,Q4KMQ2,Q13505,Q15070,Q9NX63,P45880,Q96A33,Q12981,O75844,Q00765,P46379,Q9H3K2,Q9BUR5,O95249,Q15629,Q8IXI1,O94826,Q9H2C2,Q16891,P57088,Q13636,O15258,Q6P1A2,Q9NQC3,O60499,O95202,Q9Y255,Q8N8Q8,Q9NZJ7,Q9NPA0,O14656,Q9BRK0,Q9UHD1,Q8NHH9,Q3ZCQ8,Q9BZF1,P12235,Q8N4V1,O14737,Q13190,O00743,P46109,P52789,Q8WWC4,Q9UQB8,Q8NFQ8,Q5JRA6,Q9H4A6,Q9Y5J9,P16615,O43760,Q86XL3,P30536,Q53H12,Q9Y371,P56962,O14653,Q15041,O43752,Q6UXV4,O43681,Q9UH99,Q6NUK4,Q9NZ43,O14657,Q9Y512,Q14696,Q9H6H4,Q9UBV8,Q9Y5J6,O75340,O75431,O15228,Q07812,Q9HCU5,Q8IWA4,O94901,Q12846,Q8IXJ6,P05141,P50570,P98194,P33897,O00203,P62820,O75396,Q9NR31,P50402,Q96CP7,Q9Y276,P08183,Q15392,P49755 | Processes and pathways | GO Biological process | msigdb_gobp | 521,16,527,21,541,23,26,31,545,41,42,557,50,53,562,57,59,579,69,71,73,75,591,598,98,602,105,618,110,113,117,118,124,126,139,140,142,645,145,667,154,674,677,158,161,670,672,679,682,171,172,685,692,684,173,181,179,184,193,197,204,217,214,225,244,249,250,261,275,281,314,311,323,328,334,336,346,347,348,353,354,358,364,359,372,379,403,410,429,426,433,446,452,467,470,474,477,484,495,511 | 2593,433,1529,2414,679,2278,225,645,311,670,1161,942,2489,1694,1003,353,110,1109,2187,1800,261,249,184,1163,521,2157,1981,118,2714,347,1861,452,348,1375,1955,57,1072,598,359,980,1201,124,73,1004,1984,3134,1429,2073,2752,1402,944,403,2159,1325,2491,484,1256,2753,727,1929,158,179,1006,1698,3074,1379,1634,1733,2935,197,527,426,2135,3000,1736,3175,866,2716,1602,50,682,579,1505,2138,1261,1409,511,1478,850,470,771,410,689,1838,949,2081,772,171,2445,2341,1236,214,105,2082,1868,2258,1460,1209,3176,26,446,2083,429,59,1541,2193,354,372,907,562,908,672,1965,41,1995,618,1876,1213,328,2322,244,42,2964,2837,2582,1239,495,1941,75,1085,602,674,545,1011,204,889,1013,684,2908,998,16,281,113,250,3196,2965,3149,2741,193,1216,3173,364,591,1585,379,837,1291,161,1062,139,1217,2818,692,154,1848,2704,172,1883,2177,53,474,1126,2034,3037,2297,145,1524,541,71,749,677,1156,937,98,69,3112,173,334,358,726,142,117,2036,467,3090,21,809,557,314,140,992,740,1252,840,2098,31,336,275,667,1424,976,1794,1620,2387,1047,1497,822,685,126,477,2932,1228,217,780,1281,323,23,346,181,2277,781 | 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| 3,220 |
Mitochondrial respiratory chain complex assembly | 18 | 43 | 2.066527 | 0.038779 | Q9Y276,O43676,Q9Y512,Q9H061,Q8N183,O95831,P03886,Q9P0S2,O95167,Q8N8Q8,Q15070,Q86Y39,O75880,Q96CU9,Q9BSK2,O95139,Q9Y2R0,Q9NX14 | Processes and pathways | GO Biological process | msigdb_gobp | 477,1,323,6,419,416,103,10,394,139,42,77,298,465,210,338,122,286 | 1625,1695,1,1253,1322,700,483,1136,298,338,394,1956,671,416,2439,103,3187,867,1169,42,2426,1390,1419,854,77,419,139,792,465,1752,1396,210,1718,6,1196,286,1131,1252,10,477,122,323,625 | -0.15011234602282414,-0.1796530741697238,4.3291217026971225,0.055331969068424594,0.011503046829603012,0.4880301099656987,0.8132470889449575,0.12814857045825676,1.2433090578397443,1.1193918429266982,0.9808141312665962,-0.29830712100880136,0.5307604103957996,0.9390541618071563,-0.553133878075549,2.090849287701112,-2.3231611916154886,0.330528729857457,0.11360824532721736,3.0972988744230174,-0.5380402143385864,-0.01777473199075143,-0.03243127960906722,0.344901195162577,2.431254128827567,0.9390541618071563,1.8920646818638314,0.4022821085379622,0.8552713566510017,-0.19444171825613035,-0.01777473199075143,1.5295919290991515,-0.1796530741697238,4.3291217026971225,0.09905645771621088,1.298144113646831,0.14267746792433023,0.06991835486739327,4.3291217026971225,0.8412731718875827,1.9850548401175079,1.174558901603863,0.6017675204564823 | 3,220 |
Abnormal epiphyseal ossification | 12 | 19 | 2.060241 | 0.039376 | Q14739,O00116,P56589,Q9Y5Y5,P38435,P40855,Q92968,Q7RTS9,Q9UG56,O75381,P10644,Q96HY6 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 454,697,331,174,270,587,748,147,212,370,502,380 | 697,2979,370,502,270,587,771,331,454,2263,1308,1907,147,748,380,1127,1722,212,174 | 0.4880301099656987,-1.0123137479236077,1.0224874166341895,0.7851812068774792,1.3391751012056732,0.6300975384411448,0.4166002588713612,1.1331976156562682,0.8692596729318535,-0.447753880325114,0.02612435090038817,-0.2685693060796182,1.8387488109229877,0.4452042862052327,1.0086059102080356,0.14267746792433023,-0.1796530741697238,1.5295919290991515,1.704881209746608 | 3,220 |
Alcohol binding | 6 | 17 | 2.047499 | 0.040609 | P30536,P21796,O14735,P09455,P45880,O95772 | Functions | GO Molecular function | msigdb_gomf | 197,70,265,111,50,85 | 265,1003,883,3133,979,85,2491,111,70,827,197,271,50,3176,1875,1269,677 | 1.3528340672655668,0.2151517460221033,0.3161453056172049,-1.4847663908172626,0.24406266179274372,2.3531546237426215,-0.5833609844142108,2.0380155210262614,2.5995589664368004,0.35926273373079604,1.570171930412102,1.3255071355722057,2.907101064760008,-1.9886334261219616,-0.2537190743102173,0.055331969068424594,0.5307604103957996 | 3,220 |
Intrinsic component of organelle membrane | 106 | 155 | 2.047137 | 0.040645 | Q99442,Q9P0S2,Q5XKP0,Q86YN1,Q9BTV4,Q14318,O14925,Q9BUN8,Q9H4I9,O60830,Q13505,Q15070,Q9NX63,Q96A33,Q8N2H4,Q12981,Q9Y282,O75844,Q8NBI6,Q99595,Q9H3K2,Q9BUR5,Q8TB36,Q15629,Q8IXI1,Q5BJH7,P57105,Q16799,O75192,O94826,Q16891,L0R6Q1,Q8TB61,P57088,Q15388,O75298,Q96HA9,O15258,Q6ZRP7,Q9NQC3,O60499,Q9Y2R0,Q6Y1H2,O95563,O95470,O43292,Q8N8Q8,Q9NPA0,O00767,P10321,Q9Y6N1,A0FGR8,P12235,Q8N4V1,Q9H9B4,Q9Y5Y5,O95070,Q86XL3,Q5SNT2,Q53H12,Q9UG56,P50416,Q03518,Q9Y4P3,P27824,Q15041,O43752,Q6UXV4,O76024,Q9UH99,Q96AQ8,Q9H490,O96008,O75880,Q9HC21,Q9UM00,O43808,Q9NRB3,Q9Y512,Q96ER9,P56589,Q969X5,Q9BPX6,O75431,Q9HCU5,Q8IWA4,O94901,Q6P4A7,Q9P035,Q9Y287,Q9H9P8,Q8NE86,Q9BUB7,Q9Y5Z9,Q9Y679,P98194,P33897,O43505,Q5T9L3,Q92643,Q96NB2,Q14739,Q9UH62,O14975,P51572,Q9BWH2 | Localization | GO Cellular component | msigdb_gocc | 513,10,16,19,541,536,29,32,38,37,41,42,557,53,563,562,56,57,58,64,69,71,593,75,591,76,84,94,96,598,602,102,104,105,620,108,109,110,631,117,118,122,641,129,133,137,139,142,644,646,148,657,158,161,678,174,189,193,195,204,212,213,228,242,236,244,249,250,262,275,282,292,300,298,310,316,317,322,323,325,331,341,342,348,358,364,359,378,382,391,408,406,412,415,423,429,426,437,447,448,457,454,468,460,485,500 | 657,102,644,29,460,1003,110,137,1800,437,249,317,1253,118,37,96,108,348,57,298,262,598,359,189,1201,133,129,300,2440,646,158,3124,1006,680,728,2980,236,2674,426,1736,787,213,1838,485,331,105,84,800,1209,429,703,228,1904,2474,562,41,536,454,2322,244,42,1308,1441,620,75,1514,94,602,204,76,889,1013,195,447,998,16,378,250,641,631,2119,193,1216,19,364,591,1585,563,161,1062,139,58,1217,406,593,104,693,1655,448,748,2901,341,53,282,325,109,457,710,513,64,342,1041,541,412,32,71,500,768,936,975,69,292,38,678,408,310,358,142,117,322,3160,809,557,1756,769,382,740,10,3197,1722,212,468,275,316,56,391,122,1228,242,1281,323,174,415,423,148 | 0.544982758232892,2.090849287701112,0.5591946133780552,3.361075633693647,0.8552713566510017,0.2151517460221033,2.0380155210262614,1.8920646818638314,-0.2240557615419202,0.8972068072481052,1.4073803914068117,1.1883274006382527,0.055331969068424594,2.0115511185478705,3.2106974716483787,2.1567147995211386,2.0512358149832477,1.0917521341398324,2.7410182567646277,1.2433090578397443,1.3664840566092424,0.6159377018946759,1.06407470918364,1.6106743124643152,0.08449317262514162,1.9186737066568227,1.9452503290298178,1.2433090578397443,-0.553133878075549,0.5591946133780552,1.7853014752695062,-1.4209510204632576,0.2151517460221033,0.5165275398650023,0.4594902255077705,-1.0123137479236077,1.4346001455642394,-0.6895783192988665,0.9251147879781412,-0.19444171825613035,0.4022821085379622,1.5160479135785023,-0.23888123943057013,0.8132470889449575,1.1331976156562682,2.0644481952430347,2.3661898889393695,0.38795315862879387,0.08449317262514162,0.9251147879781412,0.4880301099656987,1.4617845329488237,-0.2685693060796182,-0.5682407864248026,0.6725152692738572,3.1099250993926355,0.7148409361035052,0.8692596729318535,-0.47779711418441184,1.420994700450676,3.0972988744230174,0.02612435090038817,-0.04709964827475354,0.6017675204564823,2.4831720044145342,-0.09117605087284349,2.2092672490607383,0.6159377018946759,1.5566539160615283,2.431254128827567,0.3161453056172049,0.2151517460221033,1.5836813204612712,0.8832381475623974,0.22961279842123378,3.7822378308851308,1.0086059102080356,1.4073803914068117,0.5733960056844266,0.5875869648575647,-0.37287144055437577,1.5971821074339623,0.08449317262514162,3.5973077301556384,1.06407470918364,0.6300975384411448,-0.1206201069740683,0.6725152692738572,1.7719189526049448,0.1861959397352981,1.8920646818638314,2.7410182567646277,0.08449317262514162,0.9669038074280564,0.6300975384411448,2.090849287701112,0.5022841164890406,-0.15011234602282414,0.8832381475623974,0.4452042862052327,-0.8886275567160946,1.1193918429266982,2.7922458252893323,1.3118301474062795,1.160781120599868,2.0512358149832477,0.8692596729318535,0.4880301099656987,0.7711332727194923,2.663965486017274,1.1193918429266982,0.20067947103783892,0.7148409361035052,0.9529838262623884,3.3235678990202806,2.5995589664368004,0.7992191364595662,0.43090764101721113,0.28734545070934525,0.25850136951980746,2.62534308033295,1.2844490111299678,3.2106974716483787,0.5307604103957996,0.9669038074280564,1.215836649167216,1.0779181486196767,1.8654231014435778,2.0247872950224237,1.174558901603863,-1.7752677675371011,0.38795315862879387,0.6866340160886069,-0.19444171825613035,0.43090764101721113,1.0086059102080356,0.4594902255077705,4.3291217026971225,-3.035648908546245,-0.1796530741697238,1.5295919290991515,0.8552713566510017,1.3255071355722057,1.2020866418225167,2.753835667498494,0.9947148236194842,1.9850548401175079,0.08449317262514162,1.4346001455642394,0.055331969068424594,1.174558901603863,1.704881209746608,0.9529838262623884,0.9390541618071563,1.8387488109229877 | 3,220 |
Nuclear inner membrane | 8 | 21 | 2.039157 | 0.041434 | Q8IXM6,Q5SNT2,Q14739,O94901,Q9UH99,P50402,O75844,Q9H1E5 | Localization | GO Cellular component | msigdb_gocc | 130,195,454,359,275,470,57,30 | 57,359,1379,1571,1455,470,851,1238,1264,1575,3140,454,2908,195,130,1217,2207,541,30,275,1228 | 2.7410182567646277,1.06407470918364,-0.01777473199075143,-0.1206201069740683,-0.06177987491864927,0.8412731718875827,0.344901195162577,0.06991835486739327,0.055331969068424594,-0.1206201069740683,-1.5488459500617,0.8692596729318535,-0.9040377327922564,1.5836813204612712,1.9452503290298178,0.08449317262514162,-0.4177623935728443,0.7148409361035052,3.361075633693647,1.3255071355722057,0.08449317262514162 | 3,220 |
Passive transmembrane transporter activity | 19 | 37 | 2.03359 | 0.041993 | Q96S66,O75964,Q8NE86,Q9NW15,Q99797,O75947,Q4KMQ2,O96008,P56385,P45880,Q9UM00,Q9Y277,Q96ER9,P21796,P24539,Q9Y696,Q9C0H2,Q07812,P00846 | Functions | GO Molecular function | msigdb_gomf | 653,17,406,151,540,288,545,300,306,50,316,66,325,70,330,218,606,354,115 | 1427,288,17,300,115,1403,2159,2491,1113,70,330,1836,985,1080,947,50,1808,2081,2167,1675,306,1209,354,545,406,2684,325,653,540,655,606,916,151,2462,316,66,218 | -0.04709964827475354,1.2844490111299678,3.7453603850636794,1.2433090578397443,2.0247872950224237,-0.03243127960906722,-0.4027859480941016,-0.5833609844142108,0.14267746792433023,2.5995589664368004,1.1331976156562682,-0.23888123943057013,0.24406266179274372,0.1717011182043829,0.27292895481255514,2.907101064760008,-0.2240557615419202,-0.35793329427295245,-0.4027859480941016,-0.164876629692285,1.2295774465746885,0.08449317262514162,1.0779181486196767,0.7007425622241883,0.9669038074280564,-0.6895783192988665,1.160781120599868,0.5591946133780552,0.7148409361035052,0.5591946133780552,0.6159377018946759,0.3017508900780304,1.8253993507524382,-0.553133878075549,1.2020866418225167,2.6382243688422604,1.5160479135785023 | 3,220 |
Inner mitochondrial membrane protein complex | 41 | 85 | 2.032702 | 0.042083 | O43676,P14406,Q99623,P21912,O95167,O14949,Q5XKP0,O75964,Q9Y584,P62072,O14925,Q9NX14,O75947,Q9H4I9,O60830,Q13505,Q99643,Q8IYU8,P56385,P12236,Q99595,Q9Y512,Q9BUR5,P22695,Q53H12,Q86Y39,P24539,Q9BPX6,O95139,Q9Y5J6,P20674,Q96IX5,O75431,P03886,P13073,P56378,P00846,P09669,Q9UDW1,O14548,Q6UXV4 | Localization | GO Cellular component | msigdb_gocc | 1,2,260,266,394,13,16,17,23,26,29,286,288,38,37,41,302,175,306,185,64,323,71,329,204,77,330,342,338,346,349,223,348,103,112,237,115,371,120,369,250 | 994,369,1625,29,13,1695,1,1322,37,700,483,1597,348,1136,288,17,338,394,1956,1182,671,2439,1598,115,103,1403,522,371,2043,185,112,2,1326,577,1502,349,266,329,330,1836,3187,1700,785,543,985,1736,1808,2495,867,1675,237,306,26,41,2426,1390,602,674,204,889,16,250,77,175,406,465,223,64,260,302,342,71,38,1343,809,286,557,1252,120,477,1281,323,23,346,625 | 0.22961279842123378,1.0224874166341895,-0.15011234602282414,3.361075633693647,4.196501680534049,-0.1796530741697238,4.3291217026971225,0.011503046829603012,3.2106974716483787,0.4880301099656987,0.8132470889449575,-0.13536018457472698,1.0917521341398324,0.12814857045825676,1.2844490111299678,3.7453603850636794,1.1193918429266982,0.9808141312665962,-0.29830712100880136,0.09905645771621088,0.5307604103957996,-0.553133878075549,-0.13536018457472698,2.0247872950224237,2.090849287701112,-0.03243127960906722,0.7430072800978298,1.0224874166341895,-0.3430078305713249,1.6241579565962334,2.0380155210262614,4.3291217026971225,0.011503046829603012,0.6442470592213966,-0.09117605087284349,1.0917521341398324,1.3528340672655668,1.1331976156562682,1.1331976156562682,-0.23888123943057013,-2.3231611916154886,-0.1796530741697238,0.4022821085379622,0.7007425622241883,0.24406266179274372,-0.19444171825613035,-0.2240557615419202,-0.5833609844142108,0.330528729857457,-0.164876629692285,1.4346001455642394,1.2295774465746885,3.448371427949981,3.1099250993926355,-0.5380402143385864,-0.01777473199075143,0.6159377018946759,0.5307604103957996,1.5566539160615283,0.3161453056172049,3.7822378308851308,1.4073803914068117,2.431254128827567,1.6914484940680552,0.9669038074280564,0.8552713566510017,1.4889337304892023,2.663965486017274,1.3801250919931503,1.2433090578397443,1.1193918429266982,2.5995589664368004,3.2106974716483787,0.011503046829603012,0.38795315862879387,1.298144113646831,0.6866340160886069,0.06991835486739327,2.0115511185478705,0.8412731718875827,0.055331969068424594,1.174558901603863,3.5725469272262074,1.1055766906461557,0.6017675204564823 | 3,220 |
Calcium-binding protein | 8 | 20 | 2.025673 | 0.042798 | P43307,Q14257,P41208,P80303,Q8IYU8,Q02818,Q9BPX6,P14649 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 3,165,202,12,175,79,342,119 | 699,727,119,2980,3052,202,3,445,2082,12,79,165,2500,1680,2607,175,2453,342,2484,2185 | 0.4880301099656987,0.4594902255077705,2.0115511185478705,-1.0123137479236077,-1.1525884528897288,1.5566539160615283,4.3291217026971225,0.8832381475623974,-0.35793329427295245,4.2327374623763125,2.4052507839119524,1.7317214132284093,-0.5833609844142108,-0.164876629692285,-0.6439755827313389,1.6914484940680552,-0.553133878075549,1.1193918429266982,-0.5682407864248026,-0.4027859480941016 | 3,220 |
Nucleotide transmembrane transport | 6 | 8 | 2.025505 | 0.042815 | Q9H2D1,Q8TB61,Q9BSK2,P12236,O43808,P12235 | Processes and pathways | GO Biological process | msigdb_gobp | 99,104,210,185,317,158 | 317,403,158,185,3175,104,210,99 | 1.1883274006382527,0.9669038074280564,1.7853014752695062,1.6241579565962334,-1.9556055796511111,2.090849287701112,1.5295919290991515,2.143557307496829 | 3,220 |
Decreased absent ankle reflexes | 8 | 15 | 2.02511 | 0.042856 | P54886,Q9H6K4,O60313,Q7LG56,Q15041,P07196,P12235,O75787 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 731,7,521,496,244,535,158,760 | 521,760,1201,1729,535,158,2805,731,1605,244,802,496,1271,2455,7 | 0.7430072800978298,0.43090764101721113,0.08449317262514162,-0.19444171825613035,0.7148409361035052,1.7853014752695062,-0.796465034426316,0.4594902255077705,-0.13536018457472698,1.420994700450676,0.38795315862879387,0.7992191364595662,0.055331969068424594,-0.553133878075549,4.3291217026971225 | 3,220 |
Electron transport chain oxphos system in mitochondria | 24 | 56 | 2.022841 | 0.043089 | O43676,P14406,P21912,O95167,O14949,O75964,Q9Y6N1,P12235,O75947,Q99643,O75880,P56385,P12236,P22695,P24539,O95139,Q9UDW1,P20674,P03886,P13073,P00846,P09669,Q7KZN9,O14548 | Processes and pathways | WikiPathways | msigdb_wp | 1,2,266,394,13,17,148,158,288,302,298,306,185,329,330,338,120,349,103,112,115,371,251,369 | 994,369,1625,13,1695,1,1322,700,483,1597,1136,298,288,17,338,394,1956,1182,671,2439,1598,115,103,403,1403,371,2043,158,185,112,2,1326,577,1502,349,266,329,330,1836,3187,1700,785,985,1808,2495,867,1675,306,2426,1390,251,302,120,1424,625,148 | 0.22961279842123378,1.0224874166341895,-0.15011234602282414,4.196501680534049,-0.1796530741697238,4.3291217026971225,0.011503046829603012,0.4880301099656987,0.8132470889449575,-0.13536018457472698,0.12814857045825676,1.2433090578397443,1.2844490111299678,3.7453603850636794,1.1193918429266982,0.9808141312665962,-0.29830712100880136,0.09905645771621088,0.5307604103957996,-0.553133878075549,-0.13536018457472698,2.0247872950224237,2.090849287701112,0.9669038074280564,-0.03243127960906722,1.0224874166341895,-0.3430078305713249,1.7853014752695062,1.6241579565962334,2.0380155210262614,4.3291217026971225,0.011503046829603012,0.6442470592213966,-0.09117605087284349,1.0917521341398324,1.3528340672655668,1.1331976156562682,1.1331976156562682,-0.23888123943057013,-2.3231611916154886,-0.1796530741697238,0.4022821085379622,0.24406266179274372,-0.2240557615419202,-0.5833609844142108,0.330528729857457,-0.164876629692285,1.2295774465746885,-0.5380402143385864,-0.01777473199075143,1.4073803914068117,1.2433090578397443,2.0115511185478705,-0.03243127960906722,0.6017675204564823,1.8387488109229877 | 3,220 |
Amyloid precursor protein metabolic process | 9 | 22 | 2.016953 | 0.0437 | Q9Y287,Q15392,O75298,O95197,P35610,Q9NQC3,P62942,Q16799,P49755 | Processes and pathways | GO Biological process | msigdb_gobp | 391,495,108,15,271,117,503,94,511 | 108,15,1300,2077,271,511,1478,503,3131,1965,909,1213,495,94,856,1684,547,913,117,1159,2384,391 | 2.0512358149832477,3.868076986161342,0.02612435090038817,-0.35793329427295245,1.3255071355722057,0.7711332727194923,-0.07647199667296625,0.7851812068774792,-1.468787945000136,-0.29830712100880136,0.3017508900780304,0.08449317262514162,0.7992191364595662,2.2092672490607383,0.344901195162577,-0.164876629692285,0.7007425622241883,0.3017508900780304,2.0247872950224237,0.12814857045825676,-0.5078924419127835,0.9947148236194842 | 3,220 |
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