term stringlengths 2 121 | overlap int64 6 281 | setsize int64 7 499 | score float64 1.96 10.6 | pval float64 0 0.05 | edge stringlengths 41 1.97k | type stringclasses 5 values | subtype stringclasses 24 values | subtype_key stringclasses 24 values | edge_idxs stringlengths 11 1.17k | ann_idxs stringlengths 19 2.31k | ann_vals stringlengths 124 9.94k | sig_size int64 2.2k 3.73k |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Respiratory distress | 18 | 52 | 2.833207 | 0.004608 | P04062,Q96EY8,Q9UHX1,P53701,Q969X5,P23786,P07602,Q9NX14,P51571,P00846,Q13510,O95831,P53007,Q9NZJ7,P03886,Q9BU61,O75306,Q9Y619 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 444,129,130,195,224,228,202,238,205,174,336,402,435,118,52,507,284,321 | 991,2836,2928,1357,284,1642,691,402,174,52,444,1079,202,1644,2541,2109,2345,1319,1382,2364,228,1890,1917,3116,1862,978,205,698,435,1127,195,1386,2008,545,1868,2301,336,938,2092,877,3054,224,2143,129,1186,507,2102,238,118,130,2804,321 | 0.259957824836224,-0.8896182585745165,-0.9835064404285067,-0.031483536886932104,1.4865618640799807,-0.20514755263543638,0.6022623951675792,1.1473748361451068,1.858530966129929,2.7188747455320152,1.0358797085815543,0.17574537913353644,1.7639424137148398,-0.20514755263543638,-0.6782078857633072,-0.44541992557942717,-0.5611655605911527,-0.006899517566459099,-0.04379635542041085,-0.5741054721547378,1.6579941017796185,-0.34359088686030104,-0.35626616148383433,-1.3541323866194144,-0.3309307005463687,0.2839020389785006,1.7428249612691977,0.5906290668839881,1.0582627271580938,0.12733538946207945,1.8060702271870217,-0.04379635542041085,-0.39438303239004663,0.84388637378121,-0.3309307005463687,-0.5353336998680708,1.3454804162476888,0.3197224773216361,-0.4326375722872019,0.37917010334686796,-1.1602295266575515,1.6686297834868926,-0.45821778805072105,2.045597382439755,0.09088813912649092,0.9346274268282426,-0.4326375722872019,1.6366952363642027,2.138104690682604,2.045597382439755,-0.8496448238344031,1.399936601856205 | 3,220 |
Transport vesicle | 33 | 95 | 2.814151 | 0.004891 | O15260,O14653,O43731,O75396,Q96A57,O95249,Q9NR31,P62820,O43760,Q15907,P20339,Q9GZM5,O43752,Q9BVK6,Q9Y6Y8,P61020,Q9GZY8,P24390,O14656,Q92542,O60499,P10321,Q15363,P50897,P61026,P49755,Q13190,O00461,Q9UI14,Q9H0U4,O76024,Q8TBA6,Q9Y6B6 | Localization | GO Cellular component | msigdb_gocc | 386,131,262,391,16,4,159,419,160,161,417,40,169,428,564,557,574,445,333,588,83,596,607,217,346,220,606,360,240,502,246,121,380 | 2028,360,2850,131,333,1412,386,1078,2385,262,2481,169,160,83,3121,2941,601,391,2865,246,1227,4,1556,3078,1020,1181,1645,2893,596,693,2906,706,417,1440,445,2504,1618,1725,1619,2794,220,217,1006,1444,1384,805,723,3026,2962,2668,778,2113,557,346,848,1073,2133,2424,419,2965,839,606,1784,1896,1249,1924,1521,1419,2755,607,1522,161,1589,1470,121,588,857,16,917,1350,428,40,574,502,159,1570,2553,783,689,240,1555,775,3149,380,564 | -0.4071191788972003,1.2798074901828935,-0.902977718803364,2.035277132374322,1.356391262025119,-0.06846383507404517,1.191682042369302,0.17574537913353644,-0.5870614468875899,1.55112973446276,-0.639047126440325,1.8794538850605678,1.900341982312424,2.381575533734142,-1.3821482581844489,-0.9969905180671534,0.7524335070799955,1.1806206422725458,-0.9163547798620624,1.6046778426947736,0.05431983137085251,3.066914662698067,-0.15524415933209426,-1.2290434712719016,0.2359621060209268,0.09088813912649092,-0.20514755263543638,-0.9431619709637881,0.7639045911562469,0.6022623951675792,-0.9565922352977679,0.5789838970315193,1.102902323480814,-0.08081858685386785,1.0358797085815543,-0.6520842816930595,-0.19265001514761787,-0.2552835853157044,-0.19265001514761787,-0.8496448238344031,1.6792563279160853,1.7110813613569626,0.24796642333084454,-0.08081858685386785,-0.04379635542041085,0.4618732260759608,0.5556578942224641,-1.1191690417470768,-1.0104926710376487,-0.7569773579331421,0.4853920595025518,-0.44541992557942717,0.8324940195283494,1.3126886468759842,0.40286145775279036,0.18781487789493292,-0.45821778805072105,-0.6000335419826404,1.102902323480814,-1.0104926710376487,0.41468849354360804,0.7524335070799955,-0.2804398170297884,-0.34359088686030104,0.0421032942219953,-0.35626616148383433,-0.1303787427814899,-0.06846383507404517,-0.8098274410396861,0.7524335070799955,-0.1303787427814899,1.900341982312424,-0.16769836634567817,-0.09318740744836154,2.1073435057498435,0.7753643327515691,0.3910220068094229,3.066914662698067,0.343539301380007,-0.0191846058451589,1.0917581586074971,2.8067359148045283,0.8096758222536233,0.9459207936104235,1.9107730245237085,-0.15524415933209426,-0.6782078857633072,0.4853920595025518,0.6138839162743134,1.6366952363642027,-0.14280430054455057,0.497133220134497,-1.566251635487822,1.2248050162971191,0.8324940195283494 | 3,220 |
Intrinsic component of mitochondrial outer membrane | 9 | 13 | 2.813664 | 0.004898 | O96008,P57105,Q15388,Q8TB36,Q9UH62,P50416,Q9GZY8,Q9BWH2,Q8IWA4 | Localization | GO Cellular component | msigdb_gocc | 361,42,299,368,538,216,574,410,349 | 961,644,361,216,42,299,349,899,1347,368,410,574,538 | 0.2958549303871962,0.6718156064179176,1.2798074901828935,1.7110813613569626,2.7775132241540947,1.44332627524459,1.3017382276586456,0.3554287884663738,-0.0191846058451589,1.2688271199016639,1.1251593534589284,0.8096758222536233,0.8666377492916466 | 3,220 |
Membrane insertase activity | 8 | 11 | 2.811932 | 0.004924 | Q9NPA0,P62072,Q5J8M3,Q15070,Q9P0I2,Q8N4V1,Q8N766,Q8N8Q8 | Functions | GO Molecular function | msigdb_gomf | 65,99,676,106,369,12,611,93 | 1112,99,1388,106,676,687,12,611,93,65,369 | 0.13945776876674784,2.2299468602177206,-0.04379635542041085,2.1892093590213197,0.6254936644316497,0.6138839162743134,3.066914662698067,0.7524335070799955,2.2705556495105914,2.640284795620414,1.2688271199016639 | 3,220 |
Paroxysmal involuntary eye movements | 12 | 21 | 2.802312 | 0.005074 | P11166,Q8TB37,Q9NX14,O43676,Q9BU61,Q9NPL8,Q9Y6M9,O96000,Q86Y39,P03886,Q96CU9,O75306 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 485,461,238,2,507,149,56,215,9,52,443,284 | 2,544,284,1437,1208,215,52,485,2208,3197,2391,9,796,461,443,507,149,238,853,2927,56 | 3.066914662698067,0.84388637378121,1.4865618640799807,-0.08081858685386785,0.0665227892062105,1.7110813613569626,2.7188747455320152,0.9684750150712558,-0.49670497179853523,-2.5454072221346244,-0.5870614468875899,3.066914662698067,0.47363874018302493,1.0134542381994234,1.0470765099753365,0.9346274268282426,1.9627989908083407,1.6366952363642027,0.40286145775279036,-0.9700403690508205,2.7188747455320152 | 3,220 |
Glycosylation | 30 | 54 | 2.797908 | 0.005143 | Q86YN1,Q8NBI6,Q10472,Q9H3H5,Q9HC07,Q9UHD1,Q13724,P04844,Q9BV10,Q96JB2,P15291,Q16706,Q86SQ9,Q8N4A0,Q9Y673,O75503,P04062,Q2TAA5,O60502,O43909,O95394,Q9BT22,O75340,Q08379,Q9BXS4,O15118,P46977,O43505,O60568,P04843 | Processes and pathways | GO Biological process | msigdb_gobp | 10,157,287,423,163,689,938,680,306,304,821,952,191,192,970,827,444,965,960,455,974,213,601,741,233,498,244,499,635,755 | 498,1798,499,455,960,635,1357,601,827,974,444,755,680,821,1166,244,2280,1867,1150,1283,741,1025,287,938,2014,952,965,2628,1469,1422,1527,191,10,192,157,2993,304,1186,2101,213,306,233,1051,423,987,1961,2078,2803,163,2516,1964,689,1178,970 | 0.9459207936104235,-0.29304016007056427,0.9459207936104235,1.0134542381994234,0.2958549303871962,0.6949068177163424,-0.031483536886932104,0.7524335070799955,0.42650315136380795,0.2839020389785006,1.0358797085815543,0.5088622580027775,0.6138839162743134,0.438305468211881,0.10305061674467389,1.615359550416011,-0.5224416379826028,-0.3309307005463687,0.11519968611914616,0.017629308431583234,0.5322841082709197,0.2359621060209268,1.4757673267851918,0.3197224773216361,-0.39438303239004663,0.30779506353775943,0.2958549303871962,-0.7306539397951504,-0.09318740744836154,-0.06846383507404517,-0.1303787427814899,1.8165799953861819,3.066914662698067,1.8165799953861819,1.9211954232111927,-1.0511082792486242,1.4216507973625903,0.09088813912649092,-0.4326375722872019,1.7216715800440907,1.4216507973625903,1.647349260275544,0.21191456422852023,1.102902323480814,0.2719363502235667,-0.36895657598874093,-0.4198706745119138,-0.8496448238344031,1.900341982312424,-0.6520842816930595,-0.36895657598874093,0.6138839162743134,0.10305061674467389,0.2958549303871962 | 3,220 |
Cytochrome complex | 14 | 17 | 2.791408 | 0.005248 | O14949,P09669,O00483,O14548,P00403,Q9UDW1,Q9Y276,P14927,P22695,P14406,P20674,P08574,Q7KZN9,P13073 | Localization | GO Cellular component | msigdb_gocc | 0,388,919,324,484,138,754,837,681,6,872,820,251,31 | 919,324,0,484,820,388,2006,31,6,837,962,872,681,1460,251,138,754 | 0.33163721043497824,1.3781834901607573,3.066914662698067,0.9684750150712558,0.438305468211881,1.191682042369302,-0.39438303239004663,2.9518998178115905,3.066914662698067,0.41468849354360804,0.2958549303871962,0.37917010334686796,0.6138839162743134,-0.09318740744836154,1.5939868611964458,2.0146114032398925,0.5205792088564563 | 3,220 |
Positive regulation of autophagy | 11 | 35 | 2.790967 | 0.005255 | P21796,P09601,Q9BXS4,P49841,P05141,Q9Y371,Q86UE4,Q8TBX8,O60858,P12235,P49840 | Processes and pathways | GO Biological process | msigdb_gobp | 71,295,233,300,327,111,54,276,51,112,126 | 2236,1495,578,836,844,51,1294,1819,327,1644,1665,295,2601,112,3033,71,1559,847,2037,978,126,300,377,2881,3097,1040,1732,1733,54,276,3041,233,2515,111,2358 | -0.5095654138091176,-0.11796743909710786,0.7868127639005627,0.41468849354360804,0.40286145775279036,2.7188747455320152,0.005371772440517845,-0.30565538800449366,1.367292278230081,-0.20514755263543638,-0.21765962975220943,1.4541495566716278,-0.717517419954883,2.1585710601611257,-1.1328370545357922,2.5513083158200334,-0.15524415933209426,0.40286145775279036,-0.4071191788972003,0.2839020389785006,2.076507908811714,1.4324933636616817,1.2248050162971191,-0.9297495082703119,-1.2844419369124742,0.22394483301766654,-0.2552835853157044,-0.2552835853157044,2.7188747455320152,1.5188883744414763,-1.1328370545357922,1.647349260275544,-0.6520842816930595,2.179004735256838,-0.5611655605911527 | 3,220 |
SLC superfamily of solute carriers | 22 | 48 | 4.152066 | 0.000033 | P11166,Q9BSK2,Q70HW3,Q8TB61,P41440,Q9H2V7,Q96H78,P30825,Q9Y6C9,Q9UJS0,Q9BQT8,P16260,Q9HC07,Q8IXU6,O00400,O43772,P53985,Q9Y619,P12235,Q9H2D1,Q9UBX3,Q9NZJ7 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 504,521,3,142,272,168,42,172,450,448,188,437,209,85,95,96,98,100,363,113,117,385 | 95,950,96,1244,1038,904,1342,1110,923,504,363,702,437,172,272,1020,98,928,994,1023,2326,1171,1829,1949,1149,3,85,2362,142,42,542,188,521,2401,113,1878,762,168,2626,977,209,978,385,117,448,100,450,750 | 2.417894134039116,0.25971817742088116,2.417894134039116,0.05396445492275118,0.19198097023818944,0.2932798585657828,0.0013008185617386194,0.1406289365023446,0.2765242843820892,0.7432963349263024,1.0002438855216862,0.4905340462119068,0.8504766336813527,1.762736125125094,1.2464143567169512,0.2089929449754568,2.3825572878427748,0.2765242843820892,0.24286116834863625,0.2089929449754568,-0.4780054421063545,0.10612684878694781,-0.23299713672055136,-0.2885444250862047,0.1234049013882804,4.120055610780709,2.545835983443117,-0.49733057641843204,2.018019285747357,3.1190583891400703,0.6967457674248935,1.6840592373762224,0.7278212652439908,-0.5167270700046545,2.2392345851924724,-0.2514489150329518,0.4418649480306156,1.8017021818270835,-0.6545554493319645,0.25971817742088116,1.550650874331608,0.25971817742088116,0.9705957683905887,2.202896581642796,0.8504766336813527,2.3470255521669765,0.8504766336813527,0.45813460865092626 | 3,220 |
transporter | 18 | 61 | 3.69841 | 0.000217 | O43772,P54105,P53985,Q9Y619,P62072,O15397,O60830,Q9H2V7,Q9NR77,Q15012,Q8NFH4,Q99805,Q9H2D1,P41440,Q9Y584,Q99595,Q567V2,Q9HD45 | Functions | Panther Protein class | panther_protein_class | 96,224,98,100,164,229,7,168,143,92,241,112,113,272,93,55,28,61 | 1037,869,1665,2568,2973,229,614,2570,96,1222,859,7,1779,1135,1575,2320,959,272,910,2675,685,2546,1321,1020,98,224,1417,1021,1495,164,778,2453,92,284,28,1171,1149,1718,428,497,241,1804,1299,474,875,1001,916,1476,55,112,2337,113,168,1304,61,143,2894,1129,93,2810,100 | 0.19198097023818944,0.3266408648453037,-0.1598176269326193,-0.6346410197289641,-1.0268769036328127,1.414258732065182,0.5866360835393023,-0.6346410197289641,2.417894134039116,0.07140704367232885,0.3432470147157331,3.9815249340090473,-0.21460863651032072,0.1234049013882804,-0.10557775952910853,-0.4780054421063545,0.25971817742088116,1.2464143567169512,0.2932798585657828,-0.6946152420106493,0.50666446493495,-0.6148026217922726,0.018911776033070288,0.2089929449754568,2.3825572878427748,1.469183965403333,-0.03409254115393349,0.2089929449754568,-0.0697175034169823,1.8146366269813823,0.4255482257460382,-0.555736700872356,2.453038650438066,1.2179774753586134,3.357755058591856,0.10612684878694781,0.1234049013882804,-0.17801939264792577,0.8807392193122576,0.7587299785110654,1.3727347700645798,-0.21460863651032072,0.03646617604599439,0.8047850051193207,0.3266408648453037,0.24286116834863625,0.2932798585657828,-0.0518758434297274,2.8825561983101466,2.2392345851924724,-0.4780054421063545,2.2392345851924724,1.8017021818270835,0.03646617604599439,2.772217490447734,2.018019285747357,-0.8788422456292129,0.1406289365023446,2.453038650438066,-0.7961460791063834,2.3470255521669765 | 3,220 |
Mitochondrial transmembrane transport | 21 | 55 | 3.504641 | 0.000457 | Q9BSK2,P00846,O60830,P21796,Q9BPX6,O14925,O75964,Q9H4I9,Q9UJS0,Q99595,O95831,Q9BQT8,Q6P4A7,O43772,Q9Y619,Q8IYU8,Q8WWC4,P12235,Q9H2D1,P23786,O96008 | Processes and pathways | GO Biological process | msigdb_gobp | 521,5,7,13,146,148,31,296,448,55,56,188,336,96,100,105,493,363,113,122,502 | 148,614,96,7,1519,984,1038,955,31,1108,904,1342,56,502,5,1110,956,2984,363,702,13,122,1972,2314,1115,2960,2899,1020,887,2352,994,727,2779,1469,336,105,913,2522,493,710,1584,542,55,146,188,521,113,296,2626,977,2459,448,1129,1813,100 | 1.9677900245544306,0.5866360835393023,2.417894134039116,3.9815249340090473,-0.08761798539547284,0.24286116834863625,0.19198097023818944,0.25971817742088116,3.203038238799985,0.1406289365023446,0.2932798585657828,0.0013008185617386194,2.871604565087976,0.7432963349263024,4.000152058472825,0.1406289365023446,0.25971817742088116,-1.048383343404092,1.0002438855216862,0.4905340462119068,3.637546753670695,2.1172918864293333,-0.3071892340680954,-0.4780054421063545,0.1406289365023446,-1.0054619519349215,-0.8997273591394968,0.2089929449754568,0.3099852650743845,-0.49733057641843204,0.24286116834863625,0.47435753382801293,-0.7756790296554901,-0.0518758434297274,1.0737164085829487,2.299342216911089,0.2932798585657828,-0.5950395587962956,0.7741224625935152,0.4905340462119068,-0.10557775952910853,0.6967457674248935,2.8825561983101466,1.9929548607271643,1.6840592373762224,0.7278212652439908,2.2392345851924724,1.1894042960537312,-0.6545554493319645,0.25971817742088116,-0.555736700872356,0.8504766336813527,0.1406289365023446,-0.21460863651032072,2.3470255521669765 | 3,220 |
Anion transmembrane transporter activity | 18 | 46 | 3.455397 | 0.000549 | P11166,P53985,Q9Y619,Q9NW15,P51798,P30825,Q9Y696,P21796,Q8TB61,P12235,Q9H2D1,P45880,P41440,Q9UBX3,Q9UJS0,Q9BQT8,Q9C0H2,O00400 | Functions | GO Molecular function | msigdb_gomf | 504,98,100,458,390,172,173,13,142,363,113,19,272,117,448,188,317,95 | 2196,95,2718,2570,1244,1038,1342,1110,923,2004,504,363,702,13,172,272,19,631,390,1020,98,928,1023,3163,2326,933,1171,1829,1949,142,542,1869,188,317,113,1878,2626,977,978,458,117,448,816,100,173,750 | -0.42045193619341065,2.417894134039116,-0.734987782876194,-0.6346410197289641,0.05396445492275118,0.19198097023818944,0.0013008185617386194,0.1406289365023446,0.2765242843820892,-0.32589947589414364,0.7432963349263024,1.0002438855216862,0.4905340462119068,3.637546753670695,1.762736125125094,1.2464143567169512,3.5190212542585746,0.570731465647822,0.9557152813913782,0.2089929449754568,2.3825572878427748,0.2765242843820892,0.2089929449754568,-1.892924079315361,-0.4780054421063545,0.2765242843820892,0.10612684878694781,-0.23299713672055136,-0.2885444250862047,2.018019285747357,0.6967457674248935,-0.2514489150329518,1.6840592373762224,1.1173645556010907,2.2392345851924724,-0.2514489150329518,-0.6545554493319645,0.25971817742088116,0.25971817742088116,0.8352860417348812,2.202896581642796,0.8504766336813527,0.39277227311778157,2.3470255521669765,1.762736125125094,0.45813460865092626 | 3,220 |
Protein targeting to mitochondrion | 10 | 48 | 3.212409 | 0.001316 | P62072,O60830,P55786,O14925,P30536,Q10713,Q99595,O95831,Q9NS69,Q9Y584 | Processes and pathways | GO Biological process | msigdb_gobp | 164,7,44,148,52,118,55,56,90,93 | 261,797,148,2197,614,7,984,1108,1573,700,2813,56,502,1524,2984,1226,52,2207,1164,844,44,164,1324,118,727,2999,1469,1209,1009,2901,169,1236,55,2028,2969,713,795,2459,90,587,2342,1594,2736,1735,1034,93,361,535 | 1.2747164985345982,0.39277227311778157,1.9677900245544306,-0.42045193619341065,0.5866360835393023,3.9815249340090473,0.24286116834863625,0.1406289365023446,-0.10557775952910853,0.4905340462119068,-0.816695122060931,2.871604565087976,0.7432963349263024,-0.08761798539547284,-1.048383343404092,0.07140704367232885,2.9370456548784425,-0.42045193619341065,0.10612684878694781,0.35980406748615534,3.0872947676760356,1.8146366269813823,0.018911776033070288,2.1785555702551855,0.47435753382801293,-1.069982220146501,-0.0518758434297274,0.08879436807865256,0.22595288353329337,-0.8997273591394968,1.7887407077830382,0.07140704367232885,2.8825561983101466,-0.32589947589414364,-1.0054619519349215,0.4905340462119068,0.4091841119508032,-0.555736700872356,2.476362718198995,0.6340856185045755,-0.4780054421063545,-0.10557775952910853,-0.734987782876194,-0.17801939264792577,0.2089929449754568,2.453038650438066,1.0150119726592919,0.7123045001205056 | 3,220 |
Anion transmembrane transport | 15 | 41 | 3.134204 | 0.001723 | P53985,Q9Y619,P51798,Q9UHG3,P30825,P21796,Q8TB61,P12235,Q9H2D1,P45880,P41440,Q9UBX3,P08183,Q9UJS0,Q9BQT8 | Processes and pathways | GO Biological process | msigdb_gobp | 98,100,390,9,172,13,142,363,113,19,272,117,149,448,188 | 1244,1223,1038,838,1342,1110,2635,149,923,363,702,13,172,272,19,631,390,1020,98,928,994,1023,439,3163,873,2326,933,142,542,188,113,2626,977,978,117,9,448,816,1131,100,750 | 0.05396445492275118,0.07140704367232885,0.19198097023818944,0.35980406748615534,0.0013008185617386194,0.1406289365023446,-0.6745466175994318,1.9551696478034846,0.2765242843820892,1.0002438855216862,0.4905340462119068,3.637546753670695,1.762736125125094,1.2464143567169512,3.5190212542585746,0.570731465647822,0.9557152813913782,0.2089929449754568,2.3825572878427748,0.2765242843820892,0.24286116834863625,0.2089929449754568,0.8504766336813527,-1.892924079315361,0.3266408648453037,-0.4780054421063545,0.2765242843820892,2.018019285747357,0.6967457674248935,1.6840592373762224,2.2392345851924724,-0.6545554493319645,0.25971817742088116,0.25971817742088116,2.202896581642796,3.8876483838268006,0.8504766336813527,0.39277227311778157,0.1406289365023446,2.3470255521669765,0.45813460865092626 | 3,220 |
Steroid biosynthetic process | 16 | 47 | 2.968069 | 0.002997 | P48449,Q9H3P7,Q14739,P16435,Q9H2C2,Q6P1A2,Q15392,Q03426,Q16850,P54646,Q53GQ0,O14734,P11413,P30536,Q15800,Q15125 | Processes and pathways | GO Biological process | msigdb_gobp | 89,419,195,479,166,135,8,321,139,299,461,400,307,52,57,186 | 400,950,3102,2811,1039,1929,1890,1109,307,924,1413,479,1606,2504,2671,1380,52,2119,1787,89,1532,299,2753,321,568,2290,507,195,186,2730,8,2293,2847,2554,57,139,461,135,1258,2594,2560,1368,166,419,944,855,1692 | 0.925840291261168,0.25971817742088116,-1.40575437454355,-0.816695122060931,0.19198097023818944,-0.2885444250862047,-0.26996449947284556,0.1406289365023446,1.1462854884410842,0.2765242843820892,-0.03409254115393349,0.7894740510587488,-0.12359730196853358,-0.5950395587962956,-0.6946152420106493,-0.016367138093596967,2.9370456548784425,-0.38242840524926425,-0.21460863651032072,2.476362718198995,-0.08761798539547284,1.1750660998212703,-0.7552931886481278,1.1028509503603623,0.6498149999479569,-0.45875103683278273,0.7432963349263024,1.6310438815235109,1.6972419576576543,-0.734987782876194,3.8970922624249527,-0.45875103683278273,-0.8373269556814524,-0.6148026217922726,2.849646985468308,2.0429842610179008,0.8200555833521682,2.0678507334274334,0.05396445492275118,-0.6346410197289641,-0.6148026217922726,0.0013008185617386194,1.8146366269813823,0.8958117073182634,0.2765242843820892,0.35980406748615534,-0.1598176269326193 | 3,220 |
Phospholipid metabolism | 18 | 54 | 2.960763 | 0.003069 | P43304,Q8IV08,Q6P1A2,Q96N66,Q8N2A8,O96017,P35790,Q8WUK0,Q9NUQ2,Q9HBU6,O95674,Q9NPH0,Q10713,Q9NQZ5,Q9BVG9,O94830,Q9C0D9,Q8NCC3 | Processes and pathways | Reactome Pathways | msigdb_reactome | 33,294,135,295,41,478,311,462,464,17,371,21,118,120,543,466,351,64 | 2148,752,696,1193,1698,466,371,478,1226,2077,908,311,775,704,33,1789,910,2612,2012,618,2422,118,2288,1209,135,3195,294,2430,41,2095,1075,64,1175,1360,462,1151,1651,295,1807,1870,1098,1724,2302,543,2030,351,1181,17,1267,21,120,783,464,562 | -0.4014060235952034,0.4418649480306156,0.4905340462119068,0.08879436807865256,-0.17801939264792577,0.8047850051193207,0.985438559898124,0.7894740510587488,0.07140704367232885,-0.3635184931943372,0.2932798585657828,1.131842665374428,0.4255482257460382,0.4905340462119068,3.1925975641036697,-0.21460863651032072,0.2932798585657828,-0.6545554493319645,-0.32589947589414364,0.5866360835393023,-0.5361955620517158,2.1785555702551855,-0.45875103683278273,0.08879436807865256,2.0678507334274334,-2.351040992278266,1.1894042960537312,-0.5361955620517158,3.1190583891400703,-0.3635184931943372,0.17491657237536232,2.749927184602673,0.10612684878694781,0.0013008185617386194,0.8200555833521682,0.1234049013882804,-0.1416770949560075,1.1894042960537312,-0.21460863651032072,-0.2514489150329518,0.1577993598585383,-0.17801939264792577,-0.45875103683278273,0.6967457674248935,-0.32589947589414364,1.0444373301938752,0.10612684878694781,3.578537157606604,0.05396445492275118,3.5190212542585746,2.166350040724043,0.4255482257460382,0.8200555833521682,0.6655012966181437 | 3,220 |
Anion transport | 26 | 71 | 2.849652 | 0.004377 | P11166,P51798,Q9UHG3,P21796,Q8TB61,P45880,P41440,P08183,P07602,P30825,Q9Y696,P30536,Q9UJS0,Q13546,Q9BQT8,Q9C0H2,Q9NW15,P14174,O00400,P54105,P53985,Q9Y619,P12235,Q9H2D1,Q9UBX3,Q9NZJ7 | Processes and pathways | GO Biological process | msigdb_gobp | 504,390,9,13,142,19,272,149,288,172,173,52,448,439,188,317,458,467,95,224,98,100,363,113,117,385 | 2196,95,2718,2570,1244,870,1223,1038,838,1342,3153,1110,2635,288,149,923,2004,3096,504,363,702,467,13,1380,52,172,272,19,631,390,1020,98,224,928,994,1023,1680,439,3163,873,708,2326,659,933,1171,1829,1949,142,542,1869,188,317,1509,113,1878,762,2626,977,978,1267,458,385,117,9,1692,448,816,1131,100,173,750 | -0.42045193619341065,2.417894134039116,-0.734987782876194,-0.6346410197289641,0.05396445492275118,0.3266408648453037,0.07140704367232885,0.19198097023818944,0.35980406748615534,0.0013008185617386194,-1.7914173827511248,0.1406289365023446,-0.6745466175994318,1.2037080214654023,1.9551696478034846,0.2765242843820892,-0.32589947589414364,-1.3826434778969552,0.7432963349263024,1.0002438855216862,0.4905340462119068,0.8047850051193207,3.637546753670695,-0.016367138093596967,2.9370456548784425,1.762736125125094,1.2464143567169512,3.5190212542585746,0.570731465647822,0.9557152813913782,0.2089929449754568,2.3825572878427748,1.469183965403333,0.2765242843820892,0.24286116834863625,0.2089929449754568,-0.1598176269326193,0.8504766336813527,-1.892924079315361,0.3266408648453037,0.4905340462119068,-0.4780054421063545,0.5387882806522121,0.2765242843820892,0.10612684878694781,-0.23299713672055136,-0.2885444250862047,2.018019285747357,0.6967457674248935,-0.2514489150329518,1.6840592373762224,1.1173645556010907,-0.0697175034169823,2.2392345851924724,-0.2514489150329518,0.4418649480306156,-0.6545554493319645,0.25971817742088116,0.25971817742088116,0.05396445492275118,0.8352860417348812,0.9705957683905887,2.202896581642796,3.8876483838268006,-0.1598176269326193,0.8504766336813527,0.39277227311778157,0.1406289365023446,2.3470255521669765,1.762736125125094,0.45813460865092626 | 3,220 |
Optic disc pallor | 13 | 54 | 2.83903 | 0.004525 | Q86Y39,P03886,O43676,P00846,O75306,Q9H6K4,Q96CU9,Q9NPL8,Q10713,O95831,Q9Y287,Q9Y6M9,Q9H061 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 323,35,4,5,185,11,110,308,118,56,153,219,24 | 1133,1969,2071,1737,4,1886,767,953,185,2149,984,1602,2745,1573,56,2152,5,35,1136,2415,1782,1845,3178,2727,390,3052,2286,321,118,2130,323,2521,483,676,1330,1055,2365,110,2967,1869,1919,485,2969,24,3012,1266,11,308,1059,1440,562,153,1813,219 | 0.1234049013882804,-0.3071892340680954,-0.3635184931943372,-0.19628289327204587,4.000152058472825,-0.26996449947284556,0.4255482257460382,0.25971817742088116,1.6972419576576543,-0.4014060235952034,0.24286116834863625,-0.12359730196853358,-0.7552931886481278,-0.10557775952910853,2.871604565087976,-0.4014060235952034,4.000152058472825,3.182140780093308,0.1234049013882804,-0.5361955620517158,-0.21460863651032072,-0.2514489150329518,-2.0760553162811117,-0.734987782876194,0.9557152813913782,-1.2015718195219365,-0.45875103683278273,1.1028509503603623,2.1785555702551855,-0.38242840524926425,1.1028509503603623,-0.5950395587962956,0.7894740510587488,0.52274910566409,0.018911776033070288,0.19198097023818944,-0.49733057641843204,2.2633454759922618,-1.0054619519349215,-0.2514489150329518,-0.26996449947284556,0.7894740510587488,-1.0054619519349215,3.4489319406648873,-1.0916744984583173,0.05396445492275118,3.696060312872202,1.1462854884410842,0.19198097023818944,-0.03409254115393349,0.6655012966181437,1.9425238010056298,-0.21460863651032072,1.4964610648684789 | 3,220 |
Secondary alcohol metabolic process | 14 | 46 | 2.830391 | 0.004649 | P48449,Q14739,O15118,Q9H2C2,Q6P1A2,Q15392,Q16850,P54646,Q9BQE5,P11413,Q15800,Q15125,P04062,Q8WTV0 | Processes and pathways | GO Biological process | msigdb_gobp | 89,195,132,166,135,8,139,299,111,307,57,186,252,94 | 132,1886,3102,2811,1134,1039,1929,1890,252,1042,307,924,479,2671,3192,823,2119,1787,89,630,1610,2923,926,1532,299,3066,2482,2753,321,2290,507,195,2820,186,2730,8,2554,57,139,135,94,2623,111,166,944,1812 | 2.0678507334274334,-0.26996449947284556,-1.40575437454355,-0.816695122060931,0.1234049013882804,0.19198097023818944,-0.2885444250862047,-0.26996449947284556,1.3028854311521958,0.19198097023818944,1.1462854884410842,0.2765242843820892,0.7894740510587488,-0.6946152420106493,-2.322778804089259,0.37631237198261697,-0.38242840524926425,-0.21460863651032072,2.476362718198995,0.570731465647822,-0.12359730196853358,-0.9629027935936514,0.2765242843820892,-0.08761798539547284,1.1750660998212703,-1.2462201842490934,-0.5753511440847348,-0.7552931886481278,1.1028509503603623,-0.45875103683278273,0.7432963349263024,1.6310438815235109,-0.816695122060931,1.6972419576576543,-0.734987782876194,3.8970922624249527,-0.6148026217922726,2.849646985468308,2.0429842610179008,2.0678507334274334,2.429630217950549,-0.6545554493319645,2.2513014055146834,1.8146366269813823,0.2765242843820892,-0.21460863651032072 | 3,220 |
Membrane lipid metabolic process | 17 | 42 | 2.778838 | 0.005455 | P07602,O15270,Q96G23,O95470,Q9NZ01,Q9H2C2,O43292,Q9NZJ7,Q9H490,Q99805,P27544,P04062,Q9Y2B2,Q8NBX0,O15269,P50897,Q8NCC3 | Processes and pathways | GO Biological process | msigdb_gobp | 288,536,65,226,260,166,230,385,530,112,403,252,575,26,316,190,64 | 316,536,230,2197,2001,226,252,1041,1931,1137,288,3149,1488,3028,2043,1606,403,1018,190,963,1354,568,1391,1209,2516,26,64,1178,2828,65,3004,1585,112,166,530,2034,1632,260,385,878,1080,575 | 1.1173645556010907,0.6967457674248935,1.414258732065182,-0.42045193619341065,-0.32589947589414364,1.455499289321254,1.3028854311521958,0.19198097023818944,-0.2885444250862047,0.1234049013882804,1.2037080214654023,-1.7414725706171341,-0.0697175034169823,-1.1353431988438676,-0.34467570745505544,-0.12359730196853358,0.925840291261168,0.2089929449754568,1.6708482172787353,0.25971817742088116,0.0013008185617386194,0.6498149999479569,-0.016367138093596967,0.08879436807865256,-0.5950395587962956,3.438860734962392,2.749927184602673,0.10612684878694781,-0.816695122060931,2.749927184602673,-1.069982220146501,-0.10557775952910853,2.2392345851924724,1.8146366269813823,0.7123045001205056,-0.32589947589414364,-0.12359730196853358,1.2888175214244626,0.9705957683905887,0.3266408648453037,0.17491657237536232,0.6498149999479569 | 3,220 |
Glycerophospholipid biosynthesis | 17 | 38 | 2.776573 | 0.005494 | P43304,Q8IV08,Q6P1A2,Q96N66,Q8N2A8,O96017,P35790,Q8WUK0,Q9NUQ2,Q9HBU6,O95674,Q9NPH0,Q9NQZ5,Q9BVG9,O94830,Q9C0D9,Q8NCC3 | Processes and pathways | Reactome Pathways | msigdb_reactome | 33,294,135,295,41,478,311,462,464,17,371,21,120,543,466,351,64 | 752,696,1193,1698,466,371,478,1226,311,775,33,1789,910,2612,618,1209,135,3195,294,41,1075,64,1175,462,1151,1651,295,1098,1724,543,2030,351,17,1267,21,120,464,562 | 0.4418649480306156,0.4905340462119068,0.08879436807865256,-0.17801939264792577,0.8047850051193207,0.985438559898124,0.7894740510587488,0.07140704367232885,1.131842665374428,0.4255482257460382,3.1925975641036697,-0.21460863651032072,0.2932798585657828,-0.6545554493319645,0.5866360835393023,0.08879436807865256,2.0678507334274334,-2.351040992278266,1.1894042960537312,3.1190583891400703,0.17491657237536232,2.749927184602673,0.10612684878694781,0.8200555833521682,0.1234049013882804,-0.1416770949560075,1.1894042960537312,0.1577993598585383,-0.17801939264792577,0.6967457674248935,-0.32589947589414364,1.0444373301938752,3.578537157606604,0.05396445492275118,3.5190212542585746,2.166350040724043,0.8200555833521682,0.6655012966181437 | 3,220 |
Organic acid transport | 17 | 48 | 2.708464 | 0.00676 | P11166,O43772,P53985,Q9Y619,Q96H78,P30825,Q6P4A7,P31751,Q9H2D1,P41440,Q9UBX3,P08183,Q9UJS0,P23786,P14174,Q9BQT8,P09455 | Processes and pathways | GO Biological process | msigdb_gobp | 504,96,98,100,42,172,336,432,113,272,117,149,448,122,467,188,159 | 2718,950,96,1244,1223,1038,838,1342,2201,2839,3153,2635,2153,149,923,159,504,467,122,1380,172,432,1846,1416,272,2899,1020,98,928,3201,1023,873,708,2326,1949,336,42,542,188,113,1878,762,2626,977,1267,117,448,100 | -0.734987782876194,0.25971817742088116,2.417894134039116,0.05396445492275118,0.07140704367232885,0.19198097023818944,0.35980406748615534,0.0013008185617386194,-0.42045193619341065,-0.8373269556814524,-1.7914173827511248,-0.6745466175994318,-0.4014060235952034,1.9551696478034846,0.2765242843820892,1.8661068148906315,0.7432963349263024,0.8047850051193207,2.1172918864293333,-0.016367138093596967,1.762736125125094,0.8656276100768129,-0.2514489150329518,-0.03409254115393349,1.2464143567169512,-0.8997273591394968,0.2089929449754568,2.3825572878427748,0.2765242843820892,-2.7981344517611846,0.2089929449754568,0.3266408648453037,0.4905340462119068,-0.4780054421063545,-0.2885444250862047,1.0737164085829487,3.1190583891400703,0.6967457674248935,1.6840592373762224,2.2392345851924724,-0.2514489150329518,0.4418649480306156,-0.6545554493319645,0.25971817742088116,0.05396445492275118,2.202896581642796,0.8504766336813527,2.3470255521669765 | 3,220 |
Intrinsic component of mitochondrial inner membrane | 14 | 38 | 2.68924 | 0.007161 | Q13505,O60830,Q9H4I9,O75431,Q5XKP0,Q9H3K2,Q6P4A7,Q8N8Q8,O14925,Q99595,Q9P0S2,Q96NB2,Q15070,Q9Y6N1 | Localization | GO Cellular component | msigdb_gocc | 38,7,296,513,328,171,336,497,148,55,58,542,284,319 | 148,1082,7,513,1668,1342,1844,2726,994,38,284,891,1051,1209,647,328,336,893,497,913,710,1584,542,55,1099,171,296,977,814,978,854,918,58,562,980,1813,1034,319 | 1.9677900245544306,0.1577993598585383,3.9815249340090473,0.7278212652439908,-0.1598176269326193,0.0013008185617386194,-0.2514489150329518,-0.734987782876194,0.24286116834863625,3.129613103930368,1.2179774753586134,0.3099852650743845,0.19198097023818944,0.08879436807865256,0.5547822987884946,1.0883016389264322,1.0737164085829487,0.3099852650743845,0.7587299785110654,0.2932798585657828,0.4905340462119068,-0.10557775952910853,0.6967457674248935,2.8825561983101466,0.1577993598585383,1.7757520681489645,1.1894042960537312,0.25971817742088116,0.39277227311778157,0.25971817742088116,0.35980406748615534,0.2932798585657828,2.8386408942169115,0.6655012966181437,0.25971817742088116,-0.21460863651032072,0.2089929449754568,1.1173645556010907 | 3,220 |
Respirasome | 14 | 49 | 2.672165 | 0.007536 | Q86Y39,P14406,Q9Y241,P03886,O43676,Q99643,O14949,Q7KZN9,Q9UDW1,Q96CU9,Q6DKK2,Q13423,O75306,Q9Y6M9 | Localization | GO Cellular component | msigdb_gocc | 323,161,162,35,4,355,104,365,302,110,335,49,185,219 | 2691,820,903,104,2720,4,3068,953,185,2149,1602,821,2072,2467,2244,1450,2152,1523,35,2042,986,2205,459,161,3117,1344,1845,1044,557,740,3178,1381,377,2727,2545,49,1761,1795,335,365,323,110,355,1059,587,302,162,1514,219 | -0.7147620507399399,0.37631237198261697,0.2932798585657828,2.299342216911089,-0.734987782876194,4.000152058472825,-1.2686964078222256,0.25971817742088116,1.6972419576576543,-0.4014060235952034,-0.12359730196853358,0.37631237198261697,-0.3635184931943372,-0.5753511440847348,-0.4395667391423701,-0.0518758434297274,-0.4014060235952034,-0.08761798539547284,3.182140780093308,-0.34467570745505544,0.24286116834863625,-0.42045193619341065,0.8200555833521682,1.8532791398665918,-1.4757523300082407,0.0013008185617386194,-0.2514489150329518,0.19198097023818944,0.6655012966181437,0.45813460865092626,-2.0760553162811117,-0.016367138093596967,0.9705957683905887,-0.734987782876194,-0.6148026217922726,2.958717351944498,-0.19628289327204587,-0.21460863651032072,1.0737164085829487,1.0002438855216862,1.1028509503603623,2.2633454759922618,1.0297430465282826,0.19198097023818944,0.6340856185045755,1.1750660998212703,1.8404249719960983,-0.0697175034169823,1.4964610648684789 | 3,220 |
Endoplasmic reticulum golgi intermediate compartment | 11 | 54 | 2.653838 | 0.007958 | Q8N511,Q96RQ1,P80303,Q9Y282,P24390,Q15363,Q02818,Q03518,Q5BJH7,Q9Y3B3,O15260 | Localization | GO Cellular component | msigdb_gocc | 69,137,10,106,46,174,84,151,124,157,223 | 406,798,223,2378,2693,466,769,556,1197,46,2898,2475,671,1849,844,2511,2881,1350,1418,1092,10,84,151,2729,1853,263,594,1984,1944,2325,174,829,1763,124,1094,2260,1543,69,1805,2759,734,2802,137,1264,457,1182,1961,1774,879,106,1966,157,2194,948 | 0.9108453175982513,0.39277227311778157,1.469183965403333,-0.5167270700046545,-0.7147620507399399,0.8047850051193207,0.4255482257460382,0.6655012966181437,0.08879436807865256,3.0660354910464336,-0.8997273591394968,-0.5753511440847348,0.52274910566409,-0.2514489150329518,0.35980406748615534,-0.5950395587962956,-0.8788422456292129,0.0013008185617386194,-0.03409254115393349,0.1577993598585383,3.8211849551732278,2.545835983443117,1.9425238010056298,-0.734987782876194,-0.2514489150329518,1.2747164985345982,0.6183128656109925,-0.3071892340680954,-0.2885444250862047,-0.4780054421063545,1.749692739800018,0.37631237198261697,-0.19628289327204587,2.1049677855835593,0.1577993598585383,-0.4395667391423701,-0.08761798539547284,2.705119145147112,-0.21460863651032072,-0.7552931886481278,0.47435753382801293,-0.7961460791063834,2.0554297514585023,0.05396445492275118,0.8352860417348812,0.10612684878694781,-0.2885444250862047,-0.19628289327204587,0.3266408648453037,2.287365779572856,-0.2885444250862047,1.89168321088619,-0.4014060235952034,0.2765242843820892 | 3,220 |
Mitochondrial respiratory chain complex assembly | 10 | 43 | 2.607565 | 0.009119 | Q86Y39,P03886,O43676,O75306,Q96CU9,O95831,Q9H061,Q9P0S2,Q9Y6M9,Q15070 | Processes and pathways | GO Biological process | msigdb_gobp | 323,35,4,185,110,56,24,58,219,284 | 903,2720,4,1082,3068,953,185,1602,1668,821,2072,2467,1450,56,2152,35,3178,2545,1850,284,1761,1795,2130,335,323,2521,497,676,110,2732,813,521,1919,24,1726,1059,1440,587,58,1514,980,1034,219 | 0.2932798585657828,-0.734987782876194,4.000152058472825,0.1577993598585383,-1.2686964078222256,0.25971817742088116,1.6972419576576543,-0.12359730196853358,-0.1598176269326193,0.37631237198261697,-0.3635184931943372,-0.5753511440847348,-0.0518758434297274,2.871604565087976,-0.4014060235952034,3.182140780093308,-2.0760553162811117,-0.6148026217922726,-0.2514489150329518,1.2179774753586134,-0.19628289327204587,-0.21460863651032072,-0.38242840524926425,1.0737164085829487,1.1028509503603623,-0.5950395587962956,0.7587299785110654,0.52274910566409,2.2633454759922618,-0.734987782876194,0.39277227311778157,0.7278212652439908,-0.26996449947284556,3.4489319406648873,-0.17801939264792577,0.19198097023818944,-0.03409254115393349,0.6340856185045755,2.8386408942169115,-0.0697175034169823,0.25971817742088116,0.2089929449754568,1.4964610648684789 | 3,220 |
Intrinsic component of mitochondrial membrane | 19 | 55 | 2.588677 | 0.009635 | O60830,O75431,Q9BPX6,O14925,Q96NB2,Q15070,Q13505,Q9H4I9,Q9H3K2,Q99595,Q9P0S2,Q9Y6N1,Q5XKP0,Q6P4A7,Q9BUB7,P12235,P57105,Q8N8Q8,O96008 | Localization | GO Cellular component | msigdb_gocc | 7,513,146,148,542,284,38,296,171,55,58,319,328,336,476,363,239,497,502 | 148,1082,7,513,1668,1108,1573,1342,502,363,1844,2726,2899,239,994,38,284,727,891,1051,1209,647,328,336,893,1256,1174,1831,497,913,1236,710,1584,542,55,146,476,1099,2784,2969,171,296,977,814,978,3214,854,918,58,562,1217,980,1813,1034,319 | 1.9677900245544306,0.1577993598585383,3.9815249340090473,0.7278212652439908,-0.1598176269326193,0.1406289365023446,-0.10557775952910853,0.0013008185617386194,0.7432963349263024,1.0002438855216862,-0.2514489150329518,-0.734987782876194,-0.8997273591394968,1.3727347700645798,0.24286116834863625,3.129613103930368,1.2179774753586134,0.47435753382801293,0.3099852650743845,0.19198097023818944,0.08879436807865256,0.5547822987884946,1.0883016389264322,1.0737164085829487,0.3099852650743845,0.05396445492275118,0.10612684878694781,-0.23299713672055136,0.7587299785110654,0.2932798585657828,0.07140704367232885,0.4905340462119068,-0.10557775952910853,0.6967457674248935,2.8825561983101466,1.9929548607271643,0.8047850051193207,0.1577993598585383,-0.7756790296554901,-1.0054619519349215,1.7757520681489645,1.1894042960537312,0.25971817742088116,0.39277227311778157,0.25971817742088116,-3.9092083084585703,0.35980406748615534,0.2932798585657828,2.8386408942169115,0.6655012966181437,0.08879436807865256,0.25971817742088116,-0.21460863651032072,0.2089929449754568,1.1173645556010907 | 3,220 |
Inner mitochondrial membrane protein complex | 24 | 85 | 2.568732 | 0.010207 | O43676,P00846,O60830,Q9BPX6,O14925,O75964,P14406,P03886,P62072,Q13505,Q9H4I9,Q9UDW1,Q99595,O75306,Q86Y39,Q5XKP0,Q96IX5,Q9Y6M9,Q9Y584,Q99643,O14949,Q8IYU8,Q9Y5J6,Q96CU9 | Localization | GO Cellular component | msigdb_gocc | 4,5,7,146,148,31,161,35,164,38,296,302,55,185,323,328,345,219,93,355,104,105,361,110 | 2691,820,903,148,104,2720,4,3068,7,953,185,2149,513,1602,955,31,821,2072,2467,2244,1450,2152,1523,5,35,956,2042,986,2205,702,459,161,3117,1344,1845,1044,557,740,1972,2314,3178,1381,377,1526,1115,2726,2960,2727,2545,887,3064,2352,164,38,1761,1795,1051,1469,1209,647,328,893,323,105,913,110,345,55,1872,355,146,1099,296,2459,854,1059,918,587,302,1514,1813,1034,93,361,219 | -0.7147620507399399,0.37631237198261697,0.2932798585657828,1.9677900245544306,2.299342216911089,-0.734987782876194,4.000152058472825,-1.2686964078222256,3.9815249340090473,0.25971817742088116,1.6972419576576543,-0.4014060235952034,0.7278212652439908,-0.12359730196853358,0.25971817742088116,3.203038238799985,0.37631237198261697,-0.3635184931943372,-0.5753511440847348,-0.4395667391423701,-0.0518758434297274,-0.4014060235952034,-0.08761798539547284,4.000152058472825,3.182140780093308,0.25971817742088116,-0.34467570745505544,0.24286116834863625,-0.42045193619341065,0.4905340462119068,0.8200555833521682,1.8532791398665918,-1.4757523300082407,0.0013008185617386194,-0.2514489150329518,0.19198097023818944,0.6655012966181437,0.45813460865092626,-0.3071892340680954,-0.4780054421063545,-2.0760553162811117,-0.016367138093596967,0.9705957683905887,-0.08761798539547284,0.1406289365023446,-0.734987782876194,-1.0054619519349215,-0.734987782876194,-0.6148026217922726,0.3099852650743845,-1.2462201842490934,-0.49733057641843204,1.8146366269813823,3.129613103930368,-0.19628289327204587,-0.21460863651032072,0.19198097023818944,-0.0518758434297274,0.08879436807865256,0.5547822987884946,1.0883016389264322,0.3099852650743845,1.1028509503603623,2.299342216911089,0.2932798585657828,2.2633454759922618,1.0590950445972114,2.8825561983101466,-0.2514489150329518,1.0297430465282826,1.9929548607271643,0.1577993598585383,1.1894042960537312,-0.555736700872356,0.35980406748615534,0.19198097023818944,0.2932798585657828,0.6340856185045755,1.1750660998212703,-0.0697175034169823,-0.21460863651032072,0.2089929449754568,2.453038650438066,1.0150119726592919,1.4964610648684789 | 3,220 |
Cation transmembrane transporter activity | 21 | 73 | 2.553062 | 0.010678 | P31930,Q70HW3,Q8N4V1,P00846,P98194,Q96ES6,Q9Y487,Q9HD20,O75964,Q9UDW1,P30825,Q13423,Q9NW15,P13073,Q9HC07,O00400,O43772,Q9Y619,Q7KZN9,Q93050,P12235 | Functions | GO Molecular function | msigdb_gomf | 377,3,519,5,525,285,154,30,31,302,172,49,458,459,209,95,96,100,365,109,363 | 95,820,96,1244,955,31,904,1523,5,1109,1819,1110,956,2637,2112,923,2042,2205,363,459,640,1043,1044,883,3103,1972,2314,172,377,1115,1672,958,2960,631,928,887,2352,1204,1495,525,994,49,2326,933,1149,3,365,519,913,2362,2455,109,1584,285,542,2401,1878,762,2626,977,209,978,30,1188,458,1441,302,2533,1733,154,2376,100,750 | 2.417894134039116,0.37631237198261697,2.417894134039116,0.05396445492275118,0.25971817742088116,3.203038238799985,0.2932798585657828,-0.08761798539547284,4.000152058472825,0.1406289365023446,-0.23299713672055136,0.1406289365023446,0.25971817742088116,-0.6745466175994318,-0.38242840524926425,0.2765242843820892,-0.34467570745505544,-0.42045193619341065,1.0002438855216862,0.8200555833521682,0.5547822987884946,0.19198097023818944,0.19198097023818944,0.3099852650743845,-1.40575437454355,-0.3071892340680954,-0.4780054421063545,1.762736125125094,0.9705957683905887,0.1406289365023446,-0.1598176269326193,0.25971817742088116,-1.0054619519349215,0.570731465647822,0.2765242843820892,0.3099852650743845,-0.49733057641843204,0.08879436807865256,-0.0697175034169823,0.7123045001205056,0.24286116834863625,2.958717351944498,-0.4780054421063545,0.2765242843820892,0.1234049013882804,4.120055610780709,1.0002438855216862,0.7278212652439908,0.2932798585657828,-0.49733057641843204,-0.555736700872356,2.2633454759922618,-0.10557775952910853,1.2179774753586134,0.6967457674248935,-0.5167270700046545,-0.2514489150329518,0.4418649480306156,-0.6545554493319645,0.25971817742088116,1.550650874331608,0.25971817742088116,3.306571948600339,0.10612684878694781,0.8352860417348812,-0.03409254115393349,1.1750660998212703,-0.5950395587962956,-0.17801939264792577,1.9425238010056298,-0.49733057641843204,2.3470255521669765,0.45813460865092626 | 3,220 |
Protein localization to mitochondrion | 26 | 63 | 2.54968 | 0.010782 | O60830,O00165,Q9Y5J9,O14925,Q15070,P62072,P52789,Q9NX47,Q8N4H5,P55786,Q9Y6C9,P30536,P11233,Q99595,Q9H270,O95831,Q9P0J0,O95429,Q9NS69,Q9Y584,Q9Y5J6,Q8WWC4,O43615,Q8N8Q8,Q10713,O96008 | Processes and pathways | GO Biological process | msigdb_gobp | 7,261,535,148,284,164,548,431,169,44,450,52,681,55,713,56,587,700,90,93,361,493,614,497,118,502 | 261,2769,1133,797,148,2197,614,7,984,1108,1573,700,2813,56,502,1524,3155,2984,681,1782,1226,1282,52,1525,2207,1164,844,548,44,164,1324,1354,118,284,727,2999,1469,1209,1009,2901,169,497,1236,493,55,2028,2969,713,795,2459,90,431,587,2342,1594,1514,2736,1735,1034,93,361,535,450 | 1.2747164985345982,-0.7756790296554901,0.1234049013882804,0.39277227311778157,1.9677900245544306,-0.42045193619341065,0.5866360835393023,3.9815249340090473,0.24286116834863625,0.1406289365023446,-0.10557775952910853,0.4905340462119068,-0.816695122060931,2.871604565087976,0.7432963349263024,-0.08761798539547284,-1.8165893098484398,-1.048383343404092,0.50666446493495,-0.21460863651032072,0.07140704367232885,0.03646617604599439,2.9370456548784425,-0.08761798539547284,-0.42045193619341065,0.10612684878694781,0.35980406748615534,0.6811447921992041,3.0872947676760356,1.8146366269813823,0.018911776033070288,0.0013008185617386194,2.1785555702551855,1.2179774753586134,0.47435753382801293,-1.069982220146501,-0.0518758434297274,0.08879436807865256,0.22595288353329337,-0.8997273591394968,1.7887407077830382,0.7587299785110654,0.07140704367232885,0.7741224625935152,2.8825561983101466,-0.32589947589414364,-1.0054619519349215,0.4905340462119068,0.4091841119508032,-0.555736700872356,2.476362718198995,0.8807392193122576,0.6340856185045755,-0.4780054421063545,-0.10557775952910853,-0.0697175034169823,-0.734987782876194,-0.17801939264792577,0.2089929449754568,2.453038650438066,1.0150119726592919,0.7123045001205056,0.8504766336813527 | 3,220 |
Visual loss | 13 | 49 | 2.543272 | 0.010982 | P07602,P48449,P03886,P00846,P51798,O75503,P53701,Q10713,Q96JJ3,O75306,Q9NZJ7,P50897,Q13509 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 288,89,35,5,390,205,277,118,279,185,385,190,191 | 1568,1445,1133,1666,393,767,185,984,205,1520,1573,1523,2974,5,35,2790,1136,288,2153,2204,2575,1416,2542,2449,1246,775,89,190,1493,390,872,277,2286,1421,118,1681,2964,191,2088,2430,483,1863,1722,3208,2298,279,2560,1059,385 | -0.10557775952910853,-0.0518758434297274,0.1234049013882804,-0.1598176269326193,0.9407968670536033,0.4255482257460382,1.6972419576576543,0.24286116834863625,1.550650874331608,-0.08761798539547284,-0.10557775952910853,-0.08761798539547284,-1.0268769036328127,4.000152058472825,3.182140780093308,-0.7961460791063834,0.1234049013882804,1.2037080214654023,-0.4014060235952034,-0.42045193619341065,-0.6346410197289641,-0.03409254115393349,-0.6148026217922726,-0.555736700872356,0.05396445492275118,0.4255482257460382,2.476362718198995,1.6708482172787353,-0.0697175034169823,0.9557152813913782,0.3266408648453037,1.2322128552147502,-0.45875103683278273,-0.03409254115393349,2.1785555702551855,-0.1598176269326193,-1.0054619519349215,1.6708482172787353,-0.3635184931943372,-0.5361955620517158,0.7894740510587488,-0.2514489150329518,-0.17801939264792577,-3.1560901024967625,-0.45875103683278273,1.2322128552147502,-0.6148026217922726,0.19198097023818944,0.9705957683905887 | 3,220 |
Sterol metabolic process | 14 | 42 | 2.537437 | 0.011167 | P48449,Q14739,O15118,Q9H2C2,Q6P1A2,Q15392,Q16850,P54646,Q9BQE5,P11413,Q15800,Q15125,P04062,Q8WTV0 | Processes and pathways | GO Biological process | msigdb_gobp | 89,195,132,166,135,8,139,299,111,307,57,186,252,94 | 132,3102,2811,1039,1929,1890,252,1042,307,924,479,2671,3192,823,2119,3109,1787,89,1610,1532,299,3066,2482,2753,321,2290,507,195,2820,186,2730,8,2554,57,139,135,94,111,166,944,1812,1692 | 2.0678507334274334,-1.40575437454355,-0.816695122060931,0.19198097023818944,-0.2885444250862047,-0.26996449947284556,1.3028854311521958,0.19198097023818944,1.1462854884410842,0.2765242843820892,0.7894740510587488,-0.6946152420106493,-2.322778804089259,0.37631237198261697,-0.38242840524926425,-1.4289752964885551,-0.21460863651032072,2.476362718198995,-0.12359730196853358,-0.08761798539547284,1.1750660998212703,-1.2462201842490934,-0.5753511440847348,-0.7552931886481278,1.1028509503603623,-0.45875103683278273,0.7432963349263024,1.6310438815235109,-0.816695122060931,1.6972419576576543,-0.734987782876194,3.8970922624249527,-0.6148026217922726,2.849646985468308,2.0429842610179008,2.0678507334274334,2.429630217950549,2.2513014055146834,1.8146366269813823,0.2765242843820892,-0.21460863651032072,-0.1598176269326193 | 3,220 |
Ion transmembrane transporter activity | 36 | 104 | 2.532543 | 0.011324 | P11166,P31930,Q70HW3,Q8N4V1,P00846,P51798,P21796,Q8TB61,P98194,P45880,P41440,Q9Y487,Q96ES6,Q9HD20,O75964,Q9UDW1,P30825,Q9Y696,Q13423,Q9UJS0,Q9BQT8,Q9C0H2,Q9NW15,P13073,Q6P4A7,Q9HC07,O00400,O43772,P53985,Q9Y619,Q7KZN9,Q9BVC6,Q93050,P12235,Q9H2D1,Q9UBX3 | Functions | GO Molecular function | msigdb_gomf | 504,377,3,519,5,390,13,142,525,19,272,154,285,30,31,302,172,173,49,448,188,317,458,459,336,209,95,96,98,100,365,495,109,363,113,117 | 2196,95,820,2718,2570,96,1244,1038,955,31,904,1342,1523,5,1109,1819,1110,956,2637,2112,923,2042,2004,2205,504,363,702,459,640,1043,1044,883,3103,13,1972,2314,172,377,1115,1672,958,272,19,2960,631,390,1020,98,928,887,2352,1204,1495,525,994,1023,49,3163,827,2326,933,1171,1829,1949,336,1149,3,365,519,913,2362,142,2455,109,1584,285,542,1869,188,495,317,2401,113,1878,762,2626,977,209,978,30,1188,458,1441,117,302,2533,448,1733,816,154,2376,100,173,750 | -0.42045193619341065,2.417894134039116,0.37631237198261697,-0.734987782876194,-0.6346410197289641,2.417894134039116,0.05396445492275118,0.19198097023818944,0.25971817742088116,3.203038238799985,0.2932798585657828,0.0013008185617386194,-0.08761798539547284,4.000152058472825,0.1406289365023446,-0.23299713672055136,0.1406289365023446,0.25971817742088116,-0.6745466175994318,-0.38242840524926425,0.2765242843820892,-0.34467570745505544,-0.32589947589414364,-0.42045193619341065,0.7432963349263024,1.0002438855216862,0.4905340462119068,0.8200555833521682,0.5547822987884946,0.19198097023818944,0.19198097023818944,0.3099852650743845,-1.40575437454355,3.637546753670695,-0.3071892340680954,-0.4780054421063545,1.762736125125094,0.9705957683905887,0.1406289365023446,-0.1598176269326193,0.25971817742088116,1.2464143567169512,3.5190212542585746,-1.0054619519349215,0.570731465647822,0.9557152813913782,0.2089929449754568,2.3825572878427748,0.2765242843820892,0.3099852650743845,-0.49733057641843204,0.08879436807865256,-0.0697175034169823,0.7123045001205056,0.24286116834863625,0.2089929449754568,2.958717351944498,-1.892924079315361,0.37631237198261697,-0.4780054421063545,0.2765242843820892,0.10612684878694781,-0.23299713672055136,-0.2885444250862047,1.0737164085829487,0.1234049013882804,4.120055610780709,1.0002438855216862,0.7278212652439908,0.2932798585657828,-0.49733057641843204,2.018019285747357,-0.555736700872356,2.2633454759922618,-0.10557775952910853,1.2179774753586134,0.6967457674248935,-0.2514489150329518,1.6840592373762224,0.7741224625935152,1.1173645556010907,-0.5167270700046545,2.2392345851924724,-0.2514489150329518,0.4418649480306156,-0.6545554493319645,0.25971817742088116,1.550650874331608,0.25971817742088116,3.306571948600339,0.10612684878694781,0.8352860417348812,-0.03409254115393349,2.202896581642796,1.1750660998212703,-0.5950395587962956,0.8504766336813527,-0.17801939264792577,0.39277227311778157,1.9425238010056298,-0.49733057641843204,2.3470255521669765,1.762736125125094,0.45813460865092626 | 3,220 |
Mitochondrial protein import | 15 | 36 | 2.522297 | 0.011659 | P62072,Q13505,O60830,O75431,Q8N4H5,Q9Y5J6,P21796,P12235,O14925,Q9UJS0,Q99595,Q10713,Q9NS69,Q9Y584,O96008 | Processes and pathways | Reactome Pathways | msigdb_reactome | 164,38,7,513,169,361,13,363,148,448,55,118,90,93,502 | 148,614,7,2744,513,984,1038,1108,502,956,2042,2984,363,702,13,2314,2726,926,164,118,38,727,1469,1009,169,55,2623,2459,90,918,448,1514,1034,93,361,535 | 1.9677900245544306,0.5866360835393023,3.9815249340090473,-0.7552931886481278,0.7278212652439908,0.24286116834863625,0.19198097023818944,0.1406289365023446,0.7432963349263024,0.25971817742088116,-0.34467570745505544,-1.048383343404092,1.0002438855216862,0.4905340462119068,3.637546753670695,-0.4780054421063545,-0.734987782876194,0.2765242843820892,1.8146366269813823,2.1785555702551855,3.129613103930368,0.47435753382801293,-0.0518758434297274,0.22595288353329337,1.7887407077830382,2.8825561983101466,-0.6545554493319645,-0.555736700872356,2.476362718198995,0.2932798585657828,0.8504766336813527,-0.0697175034169823,0.2089929449754568,2.453038650438066,1.0150119726592919,0.7123045001205056 | 3,220 |
Inorganic molecular entity transmembrane transporter activity | 22 | 76 | 2.519433 | 0.011754 | P31930,Q8N4V1,P00846,P51798,P21796,P45880,Q96ES6,Q9Y487,Q9HD20,O75964,Q9UDW1,Q9Y696,Q13423,Q9C0H2,Q9NW15,P13073,Q9HC07,O00400,Q7KZN9,Q93050,P12235,Q9UBX3 | Functions | GO Molecular function | msigdb_gomf | 377,519,5,390,13,19,285,154,30,31,302,173,49,317,458,459,209,95,365,109,363,117 | 2196,95,820,2570,955,31,904,1523,5,1109,1819,1110,956,2637,2112,923,2042,2004,2205,363,459,640,1043,1044,883,3103,13,1972,2314,377,1115,1672,958,19,2960,631,390,928,887,2352,1204,1495,525,994,1023,49,933,1171,365,519,913,2455,109,1584,285,1869,2028,317,2401,1878,762,2626,209,30,1188,458,1441,117,302,2533,1733,816,154,2376,173,750 | -0.42045193619341065,2.417894134039116,0.37631237198261697,-0.6346410197289641,0.25971817742088116,3.203038238799985,0.2932798585657828,-0.08761798539547284,4.000152058472825,0.1406289365023446,-0.23299713672055136,0.1406289365023446,0.25971817742088116,-0.6745466175994318,-0.38242840524926425,0.2765242843820892,-0.34467570745505544,-0.32589947589414364,-0.42045193619341065,1.0002438855216862,0.8200555833521682,0.5547822987884946,0.19198097023818944,0.19198097023818944,0.3099852650743845,-1.40575437454355,3.637546753670695,-0.3071892340680954,-0.4780054421063545,0.9705957683905887,0.1406289365023446,-0.1598176269326193,0.25971817742088116,3.5190212542585746,-1.0054619519349215,0.570731465647822,0.9557152813913782,0.2765242843820892,0.3099852650743845,-0.49733057641843204,0.08879436807865256,-0.0697175034169823,0.7123045001205056,0.24286116834863625,0.2089929449754568,2.958717351944498,0.2765242843820892,0.10612684878694781,1.0002438855216862,0.7278212652439908,0.2932798585657828,-0.555736700872356,2.2633454759922618,-0.10557775952910853,1.2179774753586134,-0.2514489150329518,-0.32589947589414364,1.1173645556010907,-0.5167270700046545,-0.2514489150329518,0.4418649480306156,-0.6545554493319645,1.550650874331608,3.306571948600339,0.10612684878694781,0.8352860417348812,-0.03409254115393349,2.202896581642796,1.1750660998212703,-0.5950395587962956,-0.17801939264792577,0.39277227311778157,1.9425238010056298,-0.49733057641843204,1.762736125125094,0.45813460865092626 | 3,220 |
Translocation | 12 | 51 | 2.496388 | 0.012547 | Q9BTX1,P62072,O60830,Q8N1F7,Q15629,Q9Y5J6,Q8NFH4,O14925,Q8NFH5,Q99595,Q9NS69,Q9Y584 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 130,164,7,428,40,361,241,148,278,55,90,93 | 1037,2195,148,2719,614,7,753,1779,2573,1575,2320,1848,2675,1200,1321,1021,2548,1495,1496,164,1823,778,40,1469,892,2220,1718,428,811,241,278,1804,1399,1547,1548,1001,446,1476,55,130,3006,1180,900,2063,90,3212,1593,2036,93,361,535 | 0.19198097023818944,-0.42045193619341065,1.9677900245544306,-0.734987782876194,0.5866360835393023,3.9815249340090473,0.4418649480306156,-0.21460863651032072,-0.6346410197289641,-0.10557775952910853,-0.4780054421063545,-0.2514489150329518,-0.6946152420106493,0.08879436807865256,0.018911776033070288,0.2089929449754568,-0.6148026217922726,-0.0697175034169823,-0.0697175034169823,1.8146366269813823,-0.23299713672055136,0.4255482257460382,3.1190583891400703,-0.0518758434297274,0.3099852650743845,-0.42045193619341065,-0.17801939264792577,0.8807392193122576,0.39277227311778157,1.3727347700645798,1.2322128552147502,-0.21460863651032072,-0.016367138093596967,-0.08761798539547284,-0.08761798539547284,0.24286116834863625,0.8504766336813527,-0.0518758434297274,2.8825561983101466,2.08024732306687,-1.069982220146501,0.10612684878694781,0.3099852650743845,-0.34467570745505544,2.476362718198995,-3.397108747586746,-0.10557775952910853,-0.32589947589414364,2.453038650438066,1.0150119726592919,0.7123045001205056 | 3,220 |
Metabolism of steroids | 13 | 47 | 2.49417 | 0.012625 | P48449,Q14739,O95772,Q9H2C2,Q15392,Q16850,Q9BWD1,Q86X55,P38435,P30536,Q15800,Q15125,P04062 | Processes and pathways | Reactome Pathways | msigdb_reactome | 89,195,133,166,8,139,50,274,210,52,57,186,252 | 3211,637,400,950,2811,1039,1888,2041,2468,133,252,924,1413,1606,2504,2671,52,2119,210,89,1577,1493,1707,1287,2753,321,3209,2290,507,195,2453,186,2730,8,780,2847,2554,57,139,461,274,1258,2594,50,166,944,1036 | -3.362056655018683,0.5547822987884946,0.925840291261168,0.25971817742088116,-0.816695122060931,0.19198097023818944,-0.26996449947284556,-0.34467570745505544,-0.5753511440847348,2.0678507334274334,1.3028854311521958,0.2765242843820892,-0.03409254115393349,-0.12359730196853358,-0.5950395587962956,-0.6946152420106493,2.9370456548784425,-0.38242840524926425,1.5371485632979602,2.476362718198995,-0.10557775952910853,-0.0697175034169823,-0.17801939264792577,0.03646617604599439,-0.7552931886481278,1.1028509503603623,-3.2581390132182744,-0.45875103683278273,0.7432963349263024,1.6310438815235109,-0.555736700872356,1.6972419576576543,-0.734987782876194,3.8970922624249527,0.4255482257460382,-0.8373269556814524,-0.6148026217922726,2.849646985468308,2.0429842610179008,0.8200555833521682,1.2464143567169512,0.05396445492275118,-0.6346410197289641,2.958717351944498,1.8146366269813823,0.2765242843820892,0.2089929449754568 | 3,220 |
Action tremor | 16 | 57 | 2.452219 | 0.014198 | P07602,Q99720,P03886,Q6PJG6,P00846,O75306,Q9NW15,Q9H6K4,Q14108,P35637,Q9NR77,Q9BUB7,P41440,Q9BRK0,Q9Y287,Q9NZJ7 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 288,2,35,415,5,185,458,11,204,206,143,476,272,447,153,385 | 2567,1666,2108,2570,1519,185,2861,1341,1573,2003,5,35,1195,739,288,2153,1935,2076,2444,2156,2504,2316,2908,206,272,2922,2818,1977,1229,1421,645,204,508,1009,1235,1799,2221,415,2430,2329,3001,2760,2829,2,447,476,11,1690,143,458,385,1103,1964,153,1515,1735,1813 | -0.6346410197289641,-0.1598176269326193,-0.38242840524926425,-0.6346410197289641,-0.08761798539547284,1.6972419576576543,-0.8580423894893902,0.0013008185617386194,-0.10557775952910853,-0.32589947589414364,4.000152058472825,3.182140780093308,0.08879436807865256,0.45813460865092626,1.2037080214654023,-0.4014060235952034,-0.2885444250862047,-0.3635184931943372,-0.555736700872356,-0.4014060235952034,-0.5950395587962956,-0.4780054421063545,-0.9206985782314582,1.550650874331608,1.2464143567169512,-0.9629027935936514,-0.816695122060931,-0.3071892340680954,0.07140704367232885,-0.03409254115393349,0.5547822987884946,1.564123358690429,0.7432963349263024,0.22595288353329337,0.07140704367232885,-0.21460863651032072,-0.42045193619341065,0.8958117073182634,-0.5361955620517158,-0.4780054421063545,-1.069982220146501,-0.7552931886481278,-0.816695122060931,4.1747248666380585,0.8504766336813527,0.8047850051193207,3.696060312872202,-0.1598176269326193,2.018019285747357,0.8352860417348812,0.9705957683905887,0.1577993598585383,-0.2885444250862047,1.9425238010056298,-0.0697175034169823,-0.17801939264792577,-0.21460863651032072 | 3,220 |
Ion transport | 31 | 58 | 2.426533 | 0.015244 | P21281,P00846,P56134,P51798,P16615,P21796,Q8NE86,Q9BPX6,P98194,P45880,O95202,Q8NE01,Q9Y487,O75964,Q9Y277,Q9H4I9,Q4KMQ2,Q9Y696,P55011,Q96AQ8,Q15904,Q14847,Q9C0H2,O75947,P06576,Q9Y6M7,Q9BVC6,Q93050,P51790,Q9H2J7,O96008 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 883,5,887,390,640,13,913,146,525,19,904,411,154,31,816,296,933,173,928,710,829,827,317,955,956,750,495,109,631,762,502 | 2196,955,31,904,502,5,1109,1819,956,2004,640,1043,883,3103,13,1972,2314,1115,1672,958,19,2960,631,390,2080,928,887,2352,1204,525,827,829,933,1171,1149,411,913,2362,109,710,1584,1869,146,495,317,1509,1878,762,296,1188,1441,2533,1733,816,154,2376,173,750 | -0.42045193619341065,0.25971817742088116,3.203038238799985,0.2932798585657828,0.7432963349263024,4.000152058472825,0.1406289365023446,-0.23299713672055136,0.25971817742088116,-0.32589947589414364,0.5547822987884946,0.19198097023818944,0.3099852650743845,-1.40575437454355,3.637546753670695,-0.3071892340680954,-0.4780054421063545,0.1406289365023446,-0.1598176269326193,0.25971817742088116,3.5190212542585746,-1.0054619519349215,0.570731465647822,0.9557152813913782,-0.3635184931943372,0.2765242843820892,0.3099852650743845,-0.49733057641843204,0.08879436807865256,0.7123045001205056,0.37631237198261697,0.37631237198261697,0.2765242843820892,0.10612684878694781,0.1234049013882804,0.9108453175982513,0.2932798585657828,-0.49733057641843204,2.2633454759922618,0.4905340462119068,-0.10557775952910853,-0.2514489150329518,1.9929548607271643,0.7741224625935152,1.1173645556010907,-0.0697175034169823,-0.2514489150329518,0.4418649480306156,1.1894042960537312,0.10612684878694781,-0.03409254115393349,-0.5950395587962956,-0.17801939264792577,0.39277227311778157,1.9425238010056298,-0.49733057641843204,1.762736125125094,0.45813460865092626 | 3,220 |
Organic anion transport | 15 | 47 | 2.379464 | 0.017338 | P11166,P07602,P53985,Q9Y619,P30825,Q8TB61,P12235,Q9H2D1,P41440,Q9UBX3,Q9UJS0,Q9NZJ7,P14174,Q9BQT8,O00400 | Processes and pathways | GO Biological process | msigdb_gobp | 504,288,98,100,172,142,363,113,272,117,448,385,467,188,95 | 95,2718,1244,1223,1038,838,1342,3153,1110,2635,288,923,3096,504,363,702,467,1380,172,272,1020,98,928,1023,1680,3163,873,708,2326,1829,1949,142,542,188,113,1878,762,2626,977,978,1267,385,117,1692,448,100,750 | 2.417894134039116,-0.734987782876194,0.05396445492275118,0.07140704367232885,0.19198097023818944,0.35980406748615534,0.0013008185617386194,-1.7914173827511248,0.1406289365023446,-0.6745466175994318,1.2037080214654023,0.2765242843820892,-1.3826434778969552,0.7432963349263024,1.0002438855216862,0.4905340462119068,0.8047850051193207,-0.016367138093596967,1.762736125125094,1.2464143567169512,0.2089929449754568,2.3825572878427748,0.2765242843820892,0.2089929449754568,-0.1598176269326193,-1.892924079315361,0.3266408648453037,0.4905340462119068,-0.4780054421063545,-0.23299713672055136,-0.2885444250862047,2.018019285747357,0.6967457674248935,1.6840592373762224,2.2392345851924724,-0.2514489150329518,0.4418649480306156,-0.6545554493319645,0.25971817742088116,0.25971817742088116,0.05396445492275118,0.9705957683905887,2.202896581642796,-0.1598176269326193,0.8504766336813527,2.3470255521669765,0.45813460865092626 | 3,220 |
Peptide binding | 12 | 71 | 2.356774 | 0.018434 | O43731,Q9NZ08,Q9BYT8,Q15392,P55786,Q9UIQ6,P24390,P42892,Q03518,Q9Y287,Q9Y584,Q8WTV0 | Functions | GO Molecular function | msigdb_gomf | 63,131,199,8,44,77,46,116,151,153,93,94 | 1037,222,869,1665,1666,2110,63,2438,1222,859,1016,1108,1136,1932,1245,670,1743,2577,2281,46,2898,2158,2605,2418,2475,1575,2161,1067,116,2922,2675,1200,805,685,2546,1321,44,2249,1495,1323,2386,151,2729,1497,2910,2256,2453,3126,727,8,808,1299,94,875,974,1332,1475,1585,3006,199,2596,692,545,1923,131,679,1309,77,153,1734,93 | 0.19198097023818944,1.469183965403333,0.3266408648453037,-0.1598176269326193,-0.1598176269326193,-0.38242840524926425,2.749927184602673,-0.555736700872356,0.07140704367232885,0.3432470147157331,0.2089929449754568,0.1406289365023446,0.1234049013882804,-0.2885444250862047,0.05396445492275118,0.52274910566409,-0.19628289327204587,-0.6346410197289641,-0.45875103683278273,3.0660354910464336,-0.8997273591394968,-0.4014060235952034,-0.6545554493319645,-0.5361955620517158,-0.5753511440847348,-0.10557775952910853,-0.4014060235952034,0.17491657237536232,2.202896581642796,-0.9629027935936514,-0.6946152420106493,0.08879436807865256,0.39277227311778157,0.50666446493495,-0.6148026217922726,0.018911776033070288,3.0872947676760356,-0.4395667391423701,-0.0697175034169823,0.018911776033070288,-0.5167270700046545,1.9425238010056298,-0.734987782876194,-0.0697175034169823,-0.9206985782314582,-0.4395667391423701,-0.555736700872356,-1.5467756603571647,0.47435753382801293,3.8970922624249527,0.39277227311778157,0.03646617604599439,2.429630217950549,0.3266408648453037,0.25971817742088116,0.018911776033070288,-0.0518758434297274,-0.10557775952910853,-1.069982220146501,1.590979480045295,-0.6346410197289641,0.50666446493495,0.6967457674248935,-0.26996449947284556,2.08024732306687,0.52274910566409,0.03646617604599439,2.6031691985779295,1.9425238010056298,-0.17801939264792577,2.453038650438066 | 3,220 |
Endopeptidase activity | 19 | 63 | 2.343798 | 0.019088 | P60900,Q9NZ08,P49721,P28070,P28074,Q99436,Q96K76,Q93009,O75844,Q4J6C6,Q9BYT8,P49720,P20618,Q9BXS4,O43292,P42892,Q16740,Q10713,Q2T9J0 | Functions | GO Molecular function | msigdb_gomf | 257,131,20,289,290,417,37,445,60,67,199,451,332,216,230,116,245,118,247 | 1666,230,2197,546,984,60,1084,1700,1453,1743,2641,332,740,2315,289,755,290,1006,2773,3133,2208,1246,116,988,1319,451,20,2123,1675,2881,2865,257,496,118,1499,2950,1500,2292,245,247,67,1009,1124,808,634,2227,3164,1177,1178,1152,2869,445,37,1955,417,2028,1098,216,199,795,131,749,1813 | -0.1598176269326193,1.414258732065182,-0.42045193619341065,0.6811447921992041,0.24286116834863625,2.772217490447734,0.1577993598585383,-0.17801939264792577,-0.0518758434297274,-0.19628289327204587,-0.6745466175994318,1.0737164085829487,0.45813460865092626,-0.4780054421063545,1.2037080214654023,0.4418649480306156,1.2037080214654023,0.22595288353329337,-0.7756790296554901,-1.5706843015800522,-0.42045193619341065,0.05396445492275118,2.202896581642796,0.24286116834863625,0.018911776033070288,0.8352860417348812,3.5190212542585746,-0.38242840524926425,-0.1598176269326193,-0.8788422456292129,-0.8580423894893902,1.2888175214244626,0.7587299785110654,2.1785555702551855,-0.0697175034169823,-0.9841375547653614,-0.0697175034169823,-0.45875103683278273,1.3448923432382656,1.3309226575327,2.7163497780943877,0.22595288353329337,0.1406289365023446,0.39277227311778157,0.570731465647822,-0.42045193619341065,-1.892924079315361,0.10612684878694781,0.10612684878694781,0.1234049013882804,-0.8580423894893902,0.8504766336813527,3.1506731692887855,-0.2885444250862047,0.8958117073182634,-0.32589947589414364,0.1577993598585383,1.510053820463283,1.590979480045295,0.4091841119508032,2.08024732306687,0.45813460865092626,-0.21460863651032072 | 3,220 |
Signaling | 8 | 17 | 2.332908 | 0.019653 | P43490,Q7Z4V5,O75475,O15173,P51858,Q96JJ3,Q8WUJ1,O00264 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 0,39,200,107,141,279,187,222 | 222,107,200,349,0,141,1354,777,1826,1356,39,1257,187,279,499,1058,879 | 1.469183965403333,2.2753668998502135,1.577566174872682,1.0444373301938752,4.817180922379399,2.03051414508415,0.0013008185617386194,0.4255482257460382,-0.23299713672055136,0.0013008185617386194,3.129613103930368,0.05396445492275118,1.6840592373762224,1.2322128552147502,0.7587299785110654,0.19198097023818944,0.3266408648453037 | 3,220 |
Mitochondrial membrane organization | 15 | 53 | 2.331947 | 0.019703 | P62072,Q13505,P52789,Q5XKP0,O75431,Q9Y5J6,Q9Y5J9,Q9H3K2,Q8WWC4,P12235,Q8N8Q8,P45880,Q9Y584,Q9NS69,Q15070 | Processes and pathways | GO Biological process | msigdb_gobp | 164,38,548,328,513,361,535,171,493,363,497,19,93,90,284 | 2769,797,767,513,1108,1573,904,2073,1110,1524,2538,3155,363,1844,2605,1282,2207,2726,1787,19,2322,1164,705,805,548,164,1354,38,284,1051,1469,1209,647,328,893,1256,1174,1831,497,493,1099,171,90,854,918,587,1594,1514,1813,1034,93,361,535 | -0.7756790296554901,0.39277227311778157,0.4255482257460382,0.7278212652439908,0.1406289365023446,-0.10557775952910853,0.2932798585657828,-0.3635184931943372,0.1406289365023446,-0.08761798539547284,-0.6148026217922726,-1.8165893098484398,1.0002438855216862,-0.2514489150329518,-0.6545554493319645,0.03646617604599439,-0.42045193619341065,-0.734987782876194,-0.21460863651032072,3.5190212542585746,-0.4780054421063545,0.10612684878694781,0.4905340462119068,0.39277227311778157,0.6811447921992041,1.8146366269813823,0.0013008185617386194,3.129613103930368,1.2179774753586134,0.19198097023818944,-0.0518758434297274,0.08879436807865256,0.5547822987884946,1.0883016389264322,0.3099852650743845,0.05396445492275118,0.10612684878694781,-0.23299713672055136,0.7587299785110654,0.7741224625935152,0.1577993598585383,1.7757520681489645,2.476362718198995,0.35980406748615534,0.2932798585657828,0.6340856185045755,-0.10557775952910853,-0.0697175034169823,-0.21460863651032072,0.2089929449754568,2.453038650438066,1.0150119726592919,0.7123045001205056 | 3,220 |
Electron transport | 15 | 52 | 2.32851 | 0.019885 | Q86Y39,Q9Y241,P03886,O43676,Q99643,O43396,O14949,Q9UDW1,O43169,Q9Y6M9,Q96CU9,Q9H1E5,Q6DKK2,O75306,Q9H3N1 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 323,162,35,4,355,225,104,302,45,219,110,144,335,185,287 | 2691,903,104,45,225,2720,4,3068,953,185,2149,1602,821,2072,2467,2244,1450,522,2152,1523,35,2042,2247,3117,1845,557,2671,740,3178,1381,377,2877,2698,2727,2545,891,1761,1795,2617,335,323,110,2397,355,475,144,287,1059,587,302,162,219 | -0.7147620507399399,0.2932798585657828,2.299342216911089,3.0660354910464336,1.455499289321254,-0.734987782876194,4.000152058472825,-1.2686964078222256,0.25971817742088116,1.6972419576576543,-0.4014060235952034,-0.12359730196853358,0.37631237198261697,-0.3635184931943372,-0.5753511440847348,-0.4395667391423701,-0.0518758434297274,0.7123045001205056,-0.4014060235952034,-0.08761798539547284,3.182140780093308,-0.34467570745505544,-0.4395667391423701,-1.4757523300082407,-0.2514489150329518,0.6655012966181437,-0.6946152420106493,0.45813460865092626,-2.0760553162811117,-0.016367138093596967,0.9705957683905887,-0.8788422456292129,-0.7147620507399399,-0.734987782876194,-0.6148026217922726,0.3099852650743845,-0.19628289327204587,-0.21460863651032072,-0.6545554493319645,1.0737164085829487,1.1028509503603623,2.2633454759922618,-0.5167270700046545,1.0297430465282826,0.8047850051193207,2.0054995641999183,1.2179774753586134,0.19198097023818944,0.6340856185045755,1.1750660998212703,1.8404249719960983,1.4964610648684789 | 3,220 |
Abnormal circulating carbohydrate concentration | 10 | 41 | 2.26754 | 0.023357 | P03886,Q70HW3,O43676,Q96CU9,Q9BWD1,Q9NPL8,O95831,O75306,Q9P0S2,Q9Y6M9 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 35,3,4,110,50,308,56,185,58,219 | 2147,4,953,185,2149,1602,56,2152,2245,35,1139,3198,1845,557,740,3178,3029,2208,2727,2728,1706,2088,1009,3,1095,323,2521,676,2456,110,3032,1919,50,1267,308,1059,1440,58,448,1514,219 | -0.4014060235952034,4.000152058472825,0.25971817742088116,1.6972419576576543,-0.4014060235952034,-0.12359730196853358,2.871604565087976,-0.4014060235952034,-0.4395667391423701,3.182140780093308,0.1234049013882804,-2.5244752845196254,-0.2514489150329518,0.6655012966181437,0.45813460865092626,-2.0760553162811117,-1.1353431988438676,-0.42045193619341065,-0.734987782876194,-0.734987782876194,-0.17801939264792577,-0.3635184931943372,0.22595288353329337,4.120055610780709,0.1577993598585383,1.1028509503603623,-0.5950395587962956,0.52274910566409,-0.555736700872356,2.2633454759922618,-1.1353431988438676,-0.26996449947284556,2.958717351944498,0.05396445492275118,1.1462854884410842,0.19198097023818944,-0.03409254115393349,2.8386408942169115,0.8504766336813527,-0.0697175034169823,1.4964610648684789 | 3,220 |
SLC25 family of mitochondrial transporters | 12 | 23 | 2.262838 | 0.023646 | P16260,O43772,Q70HW3,Q9Y619,Q96H78,P12235,Q9H2D1,Q9Y6C9,Q9UBX3,Q9UJS0,Q9NZJ7,Q9BQT8 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 437,96,3,100,42,363,113,450,117,448,385,188 | 96,1244,1038,1110,363,702,437,1020,994,1023,1829,3,42,188,521,113,2626,978,385,117,448,100,450 | 2.417894134039116,0.05396445492275118,0.19198097023818944,0.1406289365023446,1.0002438855216862,0.4905340462119068,0.8504766336813527,0.2089929449754568,0.24286116834863625,0.2089929449754568,-0.23299713672055136,4.120055610780709,3.1190583891400703,1.6840592373762224,0.7278212652439908,2.2392345851924724,-0.6545554493319645,0.25971817742088116,0.9705957683905887,2.202896581642796,0.8504766336813527,2.3470255521669765,0.8504766336813527 | 3,220 |
Mitochondrial carrier domain superfamily [IPR023395] | 12 | 23 | 2.262838 | 0.023646 | P16260,O43772,Q70HW3,Q9Y619,Q96H78,P12235,Q9H2D1,Q9Y6C9,Q9UBX3,Q9UJS0,Q9NZJ7,Q9BQT8 | Sequence | InterPro Superfamily | interpro_homologous_superfamily | 437,96,3,100,42,363,113,450,117,448,385,188 | 96,1244,1038,1110,363,702,437,1020,994,1023,1829,3,42,188,521,113,2626,978,385,117,448,100,450 | 2.417894134039116,0.05396445492275118,0.19198097023818944,0.1406289365023446,1.0002438855216862,0.4905340462119068,0.8504766336813527,0.2089929449754568,0.24286116834863625,0.2089929449754568,-0.23299713672055136,4.120055610780709,3.1190583891400703,1.6840592373762224,0.7278212652439908,2.2392345851924724,-0.6545554493319645,0.25971817742088116,0.9705957683905887,2.202896581642796,0.8504766336813527,2.3470255521669765,0.8504766336813527 | 3,220 |
Mitochondrial substrate/solute carrier [IPR018108] | 12 | 23 | 2.262838 | 0.023646 | P16260,O43772,Q70HW3,Q9Y619,Q96H78,P12235,Q9H2D1,Q9Y6C9,Q9UBX3,Q9UJS0,Q9NZJ7,Q9BQT8 | Sequence | InterPro Repeat | interpro_repeat | 437,96,3,100,42,363,113,450,117,448,385,188 | 96,1244,1038,1110,363,702,437,1020,994,1023,1829,3,42,188,521,113,2626,978,385,117,448,100,450 | 2.417894134039116,0.05396445492275118,0.19198097023818944,0.1406289365023446,1.0002438855216862,0.4905340462119068,0.8504766336813527,0.2089929449754568,0.24286116834863625,0.2089929449754568,-0.23299713672055136,4.120055610780709,3.1190583891400703,1.6840592373762224,0.7278212652439908,2.2392345851924724,-0.6545554493319645,0.25971817742088116,0.9705957683905887,2.202896581642796,0.8504766336813527,2.3470255521669765,0.8504766336813527 | 3,220 |
Respiratory distress | 12 | 52 | 2.256991 | 0.024009 | P07602,P49419,P03886,Q9Y619,P00846,P23786,P53701,Q9UHX1,O95831,O75306,Q9NZJ7,P04062 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 288,160,35,100,5,122,277,246,56,185,385,252 | 1082,1483,2571,2001,185,2439,538,56,5,35,252,739,288,2155,2840,2602,2247,883,2578,2670,122,1575,2698,160,1610,886,1143,2545,1020,927,277,2249,992,994,1068,1983,568,1146,2217,891,2869,734,2492,398,2967,1919,2596,1059,385,246,2276,100 | 0.1577993598585383,-0.0697175034169823,-0.6346410197289641,-0.32589947589414364,1.6972419576576543,-0.555736700872356,0.6967457674248935,2.871604565087976,4.000152058472825,3.182140780093308,1.3028854311521958,0.45813460865092626,1.2037080214654023,-0.4014060235952034,-0.8373269556814524,-0.6545554493319645,-0.4395667391423701,0.3099852650743845,-0.6346410197289641,-0.6946152420106493,2.1172918864293333,-0.10557775952910853,-0.7147620507399399,1.8661068148906315,-0.12359730196853358,0.3099852650743845,0.1234049013882804,-0.6148026217922726,0.2089929449754568,0.2765242843820892,1.2322128552147502,-0.4395667391423701,0.24286116834863625,0.24286116834863625,0.17491657237536232,-0.3071892340680954,0.6498149999479569,0.1234049013882804,-0.42045193619341065,0.3099852650743845,-0.8580423894893902,0.47435753382801293,-0.5753511440847348,0.9407968670536033,-1.0054619519349215,-0.26996449947284556,-0.6346410197289641,0.19198097023818944,0.9705957683905887,1.3448923432382656,-0.4395667391423701,2.3470255521669765 | 3,220 |
Generalized myoclonic seizure | 16 | 45 | 2.251717 | 0.02434 | P11166,P07602,P49419,P03886,Q6PJG6,P00846,Q9Y619,Q96N66,Q8NHS3,P67870,P51649,P21912,Q14353,Q9NZJ7,P04062,Q13510 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 504,288,160,35,415,5,100,295,483,618,506,557,253,385,252,568 | 2147,1133,738,627,2001,5,35,252,288,504,1488,557,1381,842,2120,160,1706,506,3171,618,2047,1290,2797,1497,1681,568,2778,253,2679,415,2026,1398,483,2828,1332,3175,1652,295,1100,1266,2626,385,1444,1813,100 | -0.4014060235952034,0.1234049013882804,0.45813460865092626,0.570731465647822,-0.32589947589414364,4.000152058472825,3.182140780093308,1.3028854311521958,1.2037080214654023,0.7432963349263024,-0.0697175034169823,0.6655012966181437,-0.016367138093596967,0.35980406748615534,-0.38242840524926425,1.8661068148906315,-0.17801939264792577,0.7432963349263024,-2.0229893472828064,0.5866360835393023,-0.34467570745505544,0.03646617604599439,-0.7961460791063834,-0.0697175034169823,-0.1598176269326193,0.6498149999479569,-0.7756790296554901,1.3028854311521958,-0.6946152420106493,0.8958117073182634,-0.32589947589414364,-0.016367138093596967,0.7894740510587488,-0.816695122060931,0.018911776033070288,-2.0494460040865254,-0.1416770949560075,1.1894042960537312,0.1577993598585383,0.05396445492275118,-0.6545554493319645,0.9705957683905887,-0.03409254115393349,-0.21460863651032072,2.3470255521669765 | 3,220 |
Organic acid transmembrane transport | 13 | 32 | 2.2193 | 0.026466 | P11166,O43772,P53985,Q9Y619,P30825,P31751,Q9H2D1,P41440,Q9UBX3,P08183,Q9UJS0,P23786,Q9BQT8 | Processes and pathways | GO Biological process | msigdb_gobp | 504,96,98,100,172,432,113,272,117,149,448,122,188 | 96,1223,1038,838,1342,2635,149,923,504,122,1380,172,432,1846,1416,272,2899,1020,98,1023,873,2326,542,188,113,1878,762,2626,977,117,448,100 | 2.417894134039116,0.07140704367232885,0.19198097023818944,0.35980406748615534,0.0013008185617386194,-0.6745466175994318,1.9551696478034846,0.2765242843820892,0.7432963349263024,2.1172918864293333,-0.016367138093596967,1.762736125125094,0.8656276100768129,-0.2514489150329518,-0.03409254115393349,1.2464143567169512,-0.8997273591394968,0.2089929449754568,2.3825572878427748,0.2089929449754568,0.3266408648453037,-0.4780054421063545,0.6967457674248935,1.6840592373762224,2.2392345851924724,-0.2514489150329518,0.4418649480306156,-0.6545554493319645,0.25971817742088116,2.202896581642796,0.8504766336813527,2.3470255521669765 | 3,220 |
Electron transport chain oxphos system in mitochondria | 13 | 56 | 2.200606 | 0.027764 | P14406,P03886,O43676,P00846,Q9Y6N1,Q99643,O14949,Q7KZN9,Q9UDW1,P12235,O75306,Q9Y6M9,O75964 | Processes and pathways | WikiPathways | msigdb_wp | 161,35,4,5,319,355,104,365,302,363,185,219,31 | 2691,820,903,104,2720,4,3068,953,185,2149,1602,1668,955,31,821,2072,2467,2244,1450,2152,1523,5,35,1110,956,986,2205,363,702,459,161,3117,1344,1845,1044,557,740,1972,2314,3178,1381,377,1115,2960,2727,2545,887,2352,1761,1795,365,355,302,1594,219,319 | -0.7147620507399399,0.37631237198261697,0.2932798585657828,2.299342216911089,-0.734987782876194,4.000152058472825,-1.2686964078222256,0.25971817742088116,1.6972419576576543,-0.4014060235952034,-0.12359730196853358,-0.1598176269326193,0.25971817742088116,3.203038238799985,0.37631237198261697,-0.3635184931943372,-0.5753511440847348,-0.4395667391423701,-0.0518758434297274,-0.4014060235952034,-0.08761798539547284,4.000152058472825,3.182140780093308,0.1406289365023446,0.25971817742088116,0.24286116834863625,-0.42045193619341065,1.0002438855216862,0.4905340462119068,0.8200555833521682,1.8532791398665918,-1.4757523300082407,0.0013008185617386194,-0.2514489150329518,0.19198097023818944,0.6655012966181437,0.45813460865092626,-0.3071892340680954,-0.4780054421063545,-2.0760553162811117,-0.016367138093596967,0.9705957683905887,0.1406289365023446,-1.0054619519349215,-0.734987782876194,-0.6148026217922726,0.3099852650743845,-0.49733057641843204,-0.19628289327204587,-0.21460863651032072,1.0002438855216862,1.0297430465282826,1.1750660998212703,-0.10557775952910853,1.4964610648684789,1.1173645556010907 | 3,220 |
Metallopeptidase activity | 16 | 43 | 2.178756 | 0.02935 | Q9NZ08,P02786,O75976,O43847,O15372,Q9BYT8,P55786,O95630,Q9UIQ6,Q9H4A4,P42892,Q10713,Q7Z2K6,O75844,O00303,P36551 | Functions | GO Molecular function | msigdb_gomf | 131,515,514,546,697,199,44,701,77,597,116,118,729,60,719,566 | 719,1243,697,546,984,60,514,701,515,1378,3167,1743,740,2792,566,116,1046,1898,1675,1611,44,118,1009,808,1860,2557,729,1152,2266,1954,1916,1955,2028,1098,199,597,1510,1690,2102,2234,131,77,1813 | 0.47435753382801293,0.05396445492275118,0.4905340462119068,0.6811447921992041,0.24286116834863625,2.772217490447734,0.7278212652439908,0.4905340462119068,0.7278212652439908,-0.016367138093596967,-1.9445145708326446,-0.19628289327204587,0.45813460865092626,-0.7961460791063834,0.6498149999479569,2.202896581642796,0.19198097023818944,-0.26996449947284556,-0.1598176269326193,-0.12359730196853358,3.0872947676760356,2.1785555702551855,0.22595288353329337,0.39277227311778157,-0.2514489150329518,-0.6148026217922726,0.47435753382801293,0.1234049013882804,-0.4395667391423701,-0.2885444250862047,-0.26996449947284556,-0.2885444250862047,-0.32589947589414364,0.1577993598585383,1.590979480045295,0.6183128656109925,-0.0697175034169823,-0.1598176269326193,-0.3635184931943372,-0.42045193619341065,2.08024732306687,2.6031691985779295,-0.21460863651032072 | 3,220 |
Inorganic anion transport | 10 | 24 | 2.159217 | 0.030833 | P54105,P51798,Q9UHG3,Q9Y696,P21796,P45880,P30536,Q9UBX3,P08183,Q9C0H2 | Processes and pathways | GO Biological process | msigdb_gobp | 224,390,9,173,13,19,52,117,149,317 | 2196,2570,149,2004,13,52,19,631,390,224,928,994,1023,933,1171,1869,317,1509,458,117,9,816,173,750 | -0.42045193619341065,-0.6346410197289641,1.9551696478034846,-0.32589947589414364,3.637546753670695,2.9370456548784425,3.5190212542585746,0.570731465647822,0.9557152813913782,1.469183965403333,0.2765242843820892,0.24286116834863625,0.2089929449754568,0.2765242843820892,0.10612684878694781,-0.2514489150329518,1.1173645556010907,-0.0697175034169823,0.8352860417348812,2.202896581642796,3.8876483838268006,0.39277227311778157,1.762736125125094,0.45813460865092626 | 3,220 |
Mitochondrial transport | 27 | 88 | 2.1569 | 0.031013 | P00846,O60830,O75431,O00165,P45880,O14925,Q15070,O75964,P62072,Q8N4H5,P55786,P30536,Q9UJS0,Q99595,O95831,P16260,Q9NS69,Q9Y584,O43772,Q9Y5J6,Q8WWC4,P12235,Q8N8Q8,Q9UBX3,Q10713,P23786,O96008 | Processes and pathways | GO Biological process | msigdb_gobp | 5,7,513,261,19,148,284,31,164,169,44,52,448,55,56,437,90,93,96,361,493,363,497,117,118,122,502 | 261,797,148,2197,614,96,7,513,984,955,31,1108,1573,700,2813,56,502,5,2073,1110,956,1524,2538,2984,363,437,1226,122,1972,2314,2605,1282,52,2207,1115,1787,19,2960,2322,1164,705,2899,844,548,44,887,2352,164,1324,1354,118,284,727,2999,1469,1209,1009,1829,2901,1174,1831,169,497,1236,493,688,2731,55,2028,2969,713,795,2459,3214,90,587,2342,117,1594,448,1129,1514,2736,1735,1034,93,361,535 | 1.2747164985345982,0.39277227311778157,1.9677900245544306,-0.42045193619341065,0.5866360835393023,2.417894134039116,3.9815249340090473,0.7278212652439908,0.24286116834863625,0.25971817742088116,3.203038238799985,0.1406289365023446,-0.10557775952910853,0.4905340462119068,-0.816695122060931,2.871604565087976,0.7432963349263024,4.000152058472825,-0.3635184931943372,0.1406289365023446,0.25971817742088116,-0.08761798539547284,-0.6148026217922726,-1.048383343404092,1.0002438855216862,0.8504766336813527,0.07140704367232885,2.1172918864293333,-0.3071892340680954,-0.4780054421063545,-0.6545554493319645,0.03646617604599439,2.9370456548784425,-0.42045193619341065,0.1406289365023446,-0.21460863651032072,3.5190212542585746,-1.0054619519349215,-0.4780054421063545,0.10612684878694781,0.4905340462119068,-0.8997273591394968,0.35980406748615534,0.6811447921992041,3.0872947676760356,0.3099852650743845,-0.49733057641843204,1.8146366269813823,0.018911776033070288,0.0013008185617386194,2.1785555702551855,1.2179774753586134,0.47435753382801293,-1.069982220146501,-0.0518758434297274,0.08879436807865256,0.22595288353329337,-0.23299713672055136,-0.8997273591394968,0.10612684878694781,-0.23299713672055136,1.7887407077830382,0.7587299785110654,0.07140704367232885,0.7741224625935152,0.50666446493495,-0.734987782876194,2.8825561983101466,-0.32589947589414364,-1.0054619519349215,0.4905340462119068,0.4091841119508032,-0.555736700872356,-3.9092083084585703,2.476362718198995,0.6340856185045755,-0.4780054421063545,2.202896581642796,-0.10557775952910853,0.8504766336813527,0.1406289365023446,-0.0697175034169823,-0.734987782876194,-0.17801939264792577,0.2089929449754568,2.453038650438066,1.0150119726592919,0.7123045001205056 | 3,220 |
Tetrapyrrole binding | 11 | 19 | 2.154785 | 0.031179 | Q99643,Q7KZN9,Q16850,O15173,O43169,Q96EY8,P53701,Q9NRV9,P30519,Q8WUJ1,O00264 | Functions | GO Molecular function | msigdb_gomf | 355,365,139,107,45,398,277,213,86,187,222 | 222,107,45,1039,2042,802,2578,86,277,139,433,365,187,1260,398,355,712,692,213 | 1.469183965403333,2.2753668998502135,3.0660354910464336,0.19198097023818944,-0.34467570745505544,0.39277227311778157,-0.6346410197289641,2.4996031512294077,1.2322128552147502,2.0429842610179008,0.8656276100768129,1.0002438855216862,1.6840592373762224,0.05396445492275118,0.9407968670536033,1.0297430465282826,0.4905340462119068,0.50666446493495,1.523616265744399 | 3,220 |
Increased serum pyruvate | 10 | 36 | 2.149579 | 0.031589 | P03886,Q70HW3,O43676,Q96CU9,Q9BWD1,Q9NPL8,O95831,O75306,Q9P0S2,Q9Y6M9 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 35,3,4,110,50,308,56,185,58,219 | 2147,4,953,185,2149,1602,56,2152,2245,35,1139,3198,1845,557,740,3178,2208,2727,1706,2088,1009,3,323,2521,676,110,3032,1919,50,1267,308,1059,1440,58,1514,219 | -0.4014060235952034,4.000152058472825,0.25971817742088116,1.6972419576576543,-0.4014060235952034,-0.12359730196853358,2.871604565087976,-0.4014060235952034,-0.4395667391423701,3.182140780093308,0.1234049013882804,-2.5244752845196254,-0.2514489150329518,0.6655012966181437,0.45813460865092626,-2.0760553162811117,-0.42045193619341065,-0.734987782876194,-0.17801939264792577,-0.3635184931943372,0.22595288353329337,4.120055610780709,1.1028509503603623,-0.5950395587962956,0.52274910566409,2.2633454759922618,-1.1353431988438676,-0.26996449947284556,2.958717351944498,0.05396445492275118,1.1462854884410842,0.19198097023818944,-0.03409254115393349,2.8386408942169115,-0.0697175034169823,1.4964610648684789 | 3,220 |
Alcohol biosynthetic process | 13 | 41 | 2.111344 | 0.034743 | P00374,P48449,Q14739,Q9H2C2,Q6P1A2,Q15392,Q16850,P54646,P11413,P04062,Q15800,Q15125,O15269 | Processes and pathways | GO Biological process | msigdb_gobp | 128,89,195,166,135,8,139,299,307,252,57,186,316 | 3101,316,536,3102,2811,1929,128,1890,252,2896,307,924,479,2574,2543,2119,1787,89,1532,299,2013,2753,321,568,2290,195,186,2730,8,2554,57,2555,139,135,2026,3175,2829,166,1268,2034,944 | -1.40575437454355,1.1173645556010907,0.6967457674248935,-1.40575437454355,-0.816695122060931,-0.2885444250862047,2.08024732306687,-0.26996449947284556,1.3028854311521958,-0.8997273591394968,1.1462854884410842,0.2765242843820892,0.7894740510587488,-0.6346410197289641,-0.6148026217922726,-0.38242840524926425,-0.21460863651032072,2.476362718198995,-0.08761798539547284,1.1750660998212703,-0.32589947589414364,-0.7552931886481278,1.1028509503603623,0.6498149999479569,-0.45875103683278273,1.6310438815235109,1.6972419576576543,-0.734987782876194,3.8970922624249527,-0.6148026217922726,2.849646985468308,-0.6148026217922726,2.0429842610179008,2.0678507334274334,-0.32589947589414364,-2.0494460040865254,-0.816695122060931,1.8146366269813823,0.05396445492275118,-0.32589947589414364,0.2765242843820892 | 3,220 |
Regulation of mitochondrion organization | 14 | 51 | 2.102167 | 0.035539 | Q96A26,P02786,Q9NX47,Q8N2A8,O00165,Q9H3K2,Q9UG56,P21796,P12235,P27544,Q9Y6C9,P30536,O94830,Q9NUQ9 | Processes and pathways | GO Biological process | msigdb_gobp | 228,515,431,41,261,171,562,13,363,403,450,52,466,255 | 261,1133,797,2197,767,1314,466,2470,515,2073,1110,681,363,1226,13,403,2605,1282,52,1787,1284,2322,886,1164,705,1354,1426,2488,2901,1174,1831,41,913,228,1401,876,2731,2829,1917,2969,795,171,598,2764,255,431,562,1594,1443,1735,450 | 1.2747164985345982,0.1234049013882804,0.39277227311778157,-0.42045193619341065,0.4255482257460382,0.018911776033070288,0.8047850051193207,-0.5753511440847348,0.7278212652439908,-0.3635184931943372,0.1406289365023446,0.50666446493495,1.0002438855216862,0.07140704367232885,3.637546753670695,0.925840291261168,-0.6545554493319645,0.03646617604599439,2.9370456548784425,-0.21460863651032072,0.03646617604599439,-0.4780054421063545,0.3099852650743845,0.10612684878694781,0.4905340462119068,0.0013008185617386194,-0.03409254115393349,-0.5753511440847348,-0.8997273591394968,0.10612684878694781,-0.23299713672055136,3.1190583891400703,0.2932798585657828,1.4417836384684,-0.016367138093596967,0.3266408648453037,-0.734987782876194,-0.816695122060931,-0.26996449947284556,-1.0054619519349215,0.4091841119508032,1.7757520681489645,0.6183128656109925,-0.7552931886481278,1.3028854311521958,0.8807392193122576,0.6655012966181437,-0.10557775952910853,-0.03409254115393349,-0.17801939264792577,0.8504766336813527 | 3,220 |
Muscle abnormality related to mitochondrial dysfunction | 13 | 40 | 2.098465 | 0.035864 | Q86Y39,Q9BUK6,P03886,O43676,P00846,Q7LG56,Q96CU9,P12235,Q9Y2Z4,Q9NPL8,Q9UBX3,O75306,Q9Y6M9 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 323,485,35,4,5,354,110,363,533,308,117,185,219 | 2691,4,767,953,185,2149,1602,538,2152,1523,5,35,363,1845,3178,1896,2727,1459,927,1209,354,323,2521,676,2522,110,3032,813,1919,485,2433,1267,308,1059,1440,117,980,533,680,219 | -0.7147620507399399,4.000152058472825,0.4255482257460382,0.25971817742088116,1.6972419576576543,-0.4014060235952034,-0.12359730196853358,0.6967457674248935,-0.4014060235952034,-0.08761798539547284,4.000152058472825,3.182140780093308,1.0002438855216862,-0.2514489150329518,-2.0760553162811117,-0.26996449947284556,-0.734987782876194,-0.0518758434297274,0.2765242843820892,0.08879436807865256,1.0297430465282826,1.1028509503603623,-0.5950395587962956,0.52274910566409,-0.5950395587962956,2.2633454759922618,-1.1353431988438676,0.39277227311778157,-0.26996449947284556,0.7894740510587488,-0.5361955620517158,0.05396445492275118,1.1462854884410842,0.19198097023818944,-0.03409254115393349,2.202896581642796,0.25971817742088116,0.7123045001205056,0.52274910566409,1.4964610648684789 | 3,220 |
Steroid binding | 9 | 21 | 2.06738 | 0.038698 | O15118,O95772,O15173,Q14108,P21796,P38435,P45880,P30536,O00264 | Functions | GO Molecular function | msigdb_gomf | 132,133,107,204,13,210,19,52,222 | 222,132,107,3102,1929,133,252,1109,2112,13,1606,2504,52,823,210,19,3066,204,2594,1809,2030 | 1.469183965403333,2.0678507334274334,2.2753668998502135,-1.40575437454355,-0.2885444250862047,2.0678507334274334,1.3028854311521958,0.1406289365023446,-0.38242840524926425,3.637546753670695,-0.12359730196853358,-0.5950395587962956,2.9370456548784425,0.37631237198261697,1.5371485632979602,3.5190212542585746,-1.2462201842490934,1.564123358690429,-0.6346410197289641,-0.21460863651032072,-0.32589947589414364 | 3,220 |
Dementia | 23 | 61 | 2.060001 | 0.039398 | O15118,P00846,P43243,P27544,Q5JTZ9,Q9Y287,Q9Y487,P07602,P03886,Q6Y7W6,P21912,Q13510,Q14108,P35637,Q9UHD9,Q7LG56,P22626,Q9NQZ5,Q9NZJ7,P04062,Q06787,O96008,O76024 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 132,5,516,403,541,153,154,288,35,551,557,568,204,206,600,354,242,120,385,252,645,502,501 | 1133,132,2197,2570,767,501,502,1523,5,35,252,1195,739,1042,1137,288,639,2638,3028,2156,557,242,2445,403,1381,786,1416,206,1672,958,1284,516,1706,1229,2547,3066,3067,2926,645,931,568,204,1071,541,551,354,2430,1544,2055,1363,2731,2760,3032,2829,120,385,1103,600,153,1735,154 | 0.1234049013882804,2.0678507334274334,-0.42045193619341065,-0.6346410197289641,0.4255482257460382,0.7432963349263024,0.7432963349263024,-0.08761798539547284,4.000152058472825,3.182140780093308,1.3028854311521958,0.08879436807865256,0.45813460865092626,0.19198097023818944,0.1234049013882804,1.2037080214654023,0.5547822987884946,-0.6745466175994318,-1.1353431988438676,-0.4014060235952034,0.6655012966181437,1.358829653927647,-0.555736700872356,0.925840291261168,-0.016367138093596967,0.4091841119508032,-0.03409254115393349,1.550650874331608,-0.1598176269326193,0.25971817742088116,0.03646617604599439,0.7278212652439908,-0.17801939264792577,0.07140704367232885,-0.6148026217922726,-1.2462201842490934,-1.2462201842490934,-0.9629027935936514,0.5547822987884946,0.2765242843820892,0.6498149999479569,1.564123358690429,0.17491657237536232,0.6967457674248935,0.6811447921992041,1.0297430465282826,-0.5361955620517158,-0.08761798539547284,-0.34467570745505544,0.0013008185617386194,-0.734987782876194,-0.7552931886481278,-1.1353431988438676,-0.816695122060931,2.166350040724043,0.9705957683905887,0.1577993598585383,0.6183128656109925,1.9425238010056298,-0.17801939264792577,1.9425238010056298 | 3,220 |
Abnormal activity of mitochondrial respiratory chain | 17 | 58 | 2.051308 | 0.040237 | Q86Y39,P03886,Q70HW3,O43676,P43897,Q7KZN9,P13073,Q96CU9,P21912,Q9NPL8,Q99757,Q9UBX3,O75306,Q9P0S2,Q9Y6M9,Q9Y584,O75648 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 323,35,3,4,547,365,459,110,557,308,475,117,185,58,219,93,538 | 2691,4,2940,953,185,2149,1602,538,1450,2152,35,1139,459,1845,1044,557,3178,1346,1381,1896,547,2727,2545,3063,927,1756,2088,1795,1469,3072,846,3,365,323,2521,676,1865,110,2622,2761,475,813,1919,1877,2433,1726,308,1059,1440,587,58,2807,117,980,1566,93,2600,219 | -0.7147620507399399,4.000152058472825,-0.9841375547653614,0.25971817742088116,1.6972419576576543,-0.4014060235952034,-0.12359730196853358,0.6967457674248935,-0.0518758434297274,-0.4014060235952034,3.182140780093308,0.1234049013882804,0.8200555833521682,-0.2514489150329518,0.19198097023818944,0.6655012966181437,-2.0760553162811117,0.0013008185617386194,-0.016367138093596967,-0.26996449947284556,0.6811447921992041,-0.734987782876194,-0.6148026217922726,-1.2462201842490934,0.2765242843820892,-0.19628289327204587,-0.3635184931943372,-0.21460863651032072,-0.0518758434297274,-1.2686964078222256,0.35980406748615534,4.120055610780709,1.0002438855216862,1.1028509503603623,-0.5950395587962956,0.52274910566409,-0.2514489150329518,2.2633454759922618,-0.6545554493319645,-0.7552931886481278,0.8047850051193207,0.39277227311778157,-0.26996449947284556,-0.2514489150329518,-0.5361955620517158,-0.17801939264792577,1.1462854884410842,0.19198097023818944,-0.03409254115393349,0.6340856185045755,2.8386408942169115,-0.7961460791063834,2.202896581642796,0.25971817742088116,-0.08761798539547284,2.453038650438066,-0.6346410197289641,1.4964610648684789 | 3,220 |
Rigidity | 15 | 59 | 2.047512 | 0.040608 | P07602,P31930,Q7LG56,Q6PJG6,P00846,Q9H2C2,Q15392,Q9Y3Z3,Q9H6K4,Q96CU9,P12235,Q9BPX6,Q9Y287,Q9NZJ7,P04062 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 288,377,354,415,5,166,8,234,11,110,363,146,153,385,252 | 2071,2197,2570,1341,2770,2412,2245,5,252,739,288,363,1488,2005,2444,377,2543,2320,958,1284,2878,1200,1706,872,1230,1938,2047,2926,2797,645,1497,779,1071,8,415,551,354,2026,1624,2902,1363,110,3175,2622,2731,3032,2829,146,447,1100,166,11,1305,385,1964,153,1735,234,1813 | -0.3635184931943372,-0.42045193619341065,-0.6346410197289641,0.0013008185617386194,-0.7756790296554901,-0.5361955620517158,-0.4395667391423701,4.000152058472825,1.3028854311521958,0.45813460865092626,1.2037080214654023,1.0002438855216862,-0.0697175034169823,-0.32589947589414364,-0.555736700872356,0.9705957683905887,-0.6148026217922726,-0.4780054421063545,0.25971817742088116,0.03646617604599439,-0.8788422456292129,0.08879436807865256,-0.17801939264792577,0.3266408648453037,0.07140704367232885,-0.2885444250862047,-0.34467570745505544,-0.9629027935936514,-0.7961460791063834,0.5547822987884946,-0.0697175034169823,0.4255482257460382,0.17491657237536232,3.8970922624249527,0.8958117073182634,0.6811447921992041,1.0297430465282826,-0.32589947589414364,-0.12359730196853358,-0.8997273591394968,0.0013008185617386194,2.2633454759922618,-2.0494460040865254,-0.6545554493319645,-0.734987782876194,-1.1353431988438676,-0.816695122060931,1.9929548607271643,0.8504766336813527,0.1577993598585383,1.8146366269813823,3.696060312872202,0.03646617604599439,0.9705957683905887,-0.2885444250862047,1.9425238010056298,-0.17801939264792577,1.400449132606071,-0.21460863651032072 | 3,220 |
Proton transmembrane transporter activity | 11 | 37 | 2.045945 | 0.040762 | P31930,P00846,Q9Y487,Q7KZN9,Q9UDW1,Q93050,P12235,Q13423,Q96ES6,O00400,O75964 | Functions | GO Molecular function | msigdb_gomf | 377,5,154,365,302,109,363,49,285,95,31 | 95,820,955,31,904,1523,5,1110,956,2042,2205,363,459,1044,883,3103,1972,2314,377,1115,1672,958,2960,631,887,2352,1204,994,49,365,109,285,2626,302,2533,154,2376 | 2.417894134039116,0.37631237198261697,0.25971817742088116,3.203038238799985,0.2932798585657828,-0.08761798539547284,4.000152058472825,0.1406289365023446,0.25971817742088116,-0.34467570745505544,-0.42045193619341065,1.0002438855216862,0.8200555833521682,0.19198097023818944,0.3099852650743845,-1.40575437454355,-0.3071892340680954,-0.4780054421063545,0.9705957683905887,0.1406289365023446,-0.1598176269326193,0.25971817742088116,-1.0054619519349215,0.570731465647822,0.3099852650743845,-0.49733057641843204,0.08879436807865256,0.24286116834863625,2.958717351944498,1.0002438855216862,2.2633454759922618,1.2179774753586134,-0.6545554493319645,1.1750660998212703,-0.5950395587962956,1.9425238010056298,-0.49733057641843204 | 3,220 |
Receptor | 8 | 28 | 2.035821 | 0.041768 | Q9BUN8,Q13641,Q14108,Q9NR77,A6NIH7,Q9UQB8,Q567V2,Q8WTV0 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 165,203,204,143,22,27,28,94 | 22,2973,2241,753,1341,2665,2635,772,565,959,239,203,204,1251,28,94,1546,2027,165,1304,1335,143,1773,3039,1776,27,2971,1132 | 3.509051972736228,-1.0268769036328127,-0.4395667391423701,0.4418649480306156,0.0013008185617386194,-0.6946152420106493,-0.6745466175994318,0.4255482257460382,0.6498149999479569,0.25971817742088116,1.3727347700645798,1.564123358690429,1.564123358690429,0.05396445492275118,3.357755058591856,2.429630217950549,-0.08761798539547284,-0.32589947589414364,1.8146366269813823,0.03646617604599439,0.018911776033070288,2.018019285747357,-0.19628289327204587,-1.1573216318905468,-0.19628289327204587,3.428774762717381,-1.0054619519349215,0.1406289365023446 | 3,220 |
Lipid biosynthesis | 24 | 63 | 2.033233 | 0.042029 | Q9NZ01,Q6P1A2,Q15392,O00116,Q16850,Q9HBU6,P27544,O95864,Q9BVG9,Q9H3P7,Q96N66,P54646,Q15800,Q15125,P35790,Q96G23,Q14739,Q03426,Q53GQ0,Q8WUK0,Q9NUQ2,P48449,Q9C0D9,O95674 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 260,135,8,267,139,17,403,522,543,419,295,299,57,186,311,65,195,321,461,462,464,89,351,371 | 267,3211,637,903,752,696,2811,1039,371,522,1890,3198,924,403,311,2119,89,1789,1577,1532,1047,299,2753,321,3209,2290,195,186,2730,1467,8,2554,57,1391,139,461,135,2516,3195,1471,1258,1175,462,2055,1151,1832,65,295,1724,543,1368,896,351,419,692,17,1268,464,260,878,944,562,1692 | 1.260582173772455,-3.362056655018683,0.5547822987884946,0.2932798585657828,0.4418649480306156,0.4905340462119068,-0.816695122060931,0.19198097023818944,0.985438559898124,0.7123045001205056,-0.26996449947284556,-2.5244752845196254,0.2765242843820892,0.925840291261168,1.131842665374428,-0.38242840524926425,2.476362718198995,-0.21460863651032072,-0.10557775952910853,-0.08761798539547284,0.19198097023818944,1.1750660998212703,-0.7552931886481278,1.1028509503603623,-3.2581390132182744,-0.45875103683278273,1.6310438815235109,1.6972419576576543,-0.734987782876194,-0.0518758434297274,3.8970922624249527,-0.6148026217922726,2.849646985468308,-0.016367138093596967,2.0429842610179008,0.8200555833521682,2.0678507334274334,-0.5950395587962956,-2.351040992278266,-0.0518758434297274,0.05396445492275118,0.10612684878694781,0.8200555833521682,-0.34467570745505544,0.1234049013882804,-0.23299713672055136,2.749927184602673,1.1894042960537312,-0.17801939264792577,0.6967457674248935,0.0013008185617386194,0.3099852650743845,1.0444373301938752,0.8958117073182634,0.50666446493495,3.578537157606604,0.05396445492275118,0.8200555833521682,1.2888175214244626,0.3266408648453037,0.2765242843820892,0.6655012966181437,-0.1598176269326193 | 3,220 |
Bulbar signs | 6 | 11 | 2.017473 | 0.043646 | P07602,Q99720,P03886,P00846,P35637,P04062 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 288,2,35,5,206,252 | 2570,5,35,252,2636,288,206,516,1722,2,385 | -0.6346410197289641,4.000152058472825,3.182140780093308,1.3028854311521958,-0.6745466175994318,1.2037080214654023,1.550650874331608,0.7278212652439908,-0.17801939264792577,4.1747248666380585,0.9705957683905887 | 3,220 |
oxidoreductase | 11 | 42 | 2.012671 | 0.044149 | Q86Y39,O43396,O43676,O14949,O15254,O43169,Q8N4Q0,Q15067,O95831,O75306,Q9Y6M9 | Functions | Panther Protein class | panther_protein_class | 323,225,4,104,268,45,78,79,56,185,219 | 2691,104,268,45,225,2720,4,185,2149,2467,2244,56,2152,1523,3116,1140,2247,479,2671,2248,2581,2877,2698,2727,2545,79,891,1761,1795,2710,969,323,344,78,2397,2560,475,2139,1059,1105,219,3191 | -0.7147620507399399,2.299342216911089,1.260582173772455,3.0660354910464336,1.455499289321254,-0.734987782876194,4.000152058472825,1.6972419576576543,-0.4014060235952034,-0.5753511440847348,-0.4395667391423701,2.871604565087976,-0.4014060235952034,-0.08761798539547284,-1.452307516291366,0.1234049013882804,-0.4395667391423701,0.7894740510587488,-0.6946152420106493,-0.4395667391423701,-0.6346410197289641,-0.8788422456292129,-0.7147620507399399,-0.734987782876194,-0.6148026217922726,2.580296351023548,0.3099852650743845,-0.19628289327204587,-0.21460863651032072,-0.7147620507399399,0.25971817742088116,1.1028509503603623,1.0590950445972114,2.5917427910527433,-0.5167270700046545,-0.6148026217922726,0.8047850051193207,-0.38242840524926425,0.19198097023818944,0.1577993598585383,1.4964610648684789,-2.2946930577862656 | 3,220 |
Steroid metabolic process | 22 | 69 | 2.006264 | 0.044828 | O15118,Q6P1A2,Q15392,Q16850,O14734,Q9H3P7,Q9H2C2,P54646,P11413,P30536,Q15800,Q15125,Q14739,Q03426,Q53GQ0,P38435,P48449,Q8WTV0,O95470,P16435,Q9BQE5,P04062 | Processes and pathways | GO Biological process | msigdb_gobp | 132,135,8,139,400,419,166,299,307,52,57,186,195,321,461,210,89,94,226,479,111,252 | 400,950,132,3102,2811,1039,1929,226,1890,252,1109,1042,2983,307,924,1413,479,1606,2504,2671,2672,1380,52,3192,823,2119,210,3109,1787,89,1610,1706,1493,1532,299,3066,2482,2753,321,2882,568,2290,507,195,2820,186,2730,8,2293,2847,2554,57,139,461,2781,135,1258,94,2594,2560,111,1368,166,419,944,1812,855,1692,1964 | 0.925840291261168,0.25971817742088116,2.0678507334274334,-1.40575437454355,-0.816695122060931,0.19198097023818944,-0.2885444250862047,1.455499289321254,-0.26996449947284556,1.3028854311521958,0.1406289365023446,0.19198097023818944,-1.048383343404092,1.1462854884410842,0.2765242843820892,-0.03409254115393349,0.7894740510587488,-0.12359730196853358,-0.5950395587962956,-0.6946152420106493,-0.6946152420106493,-0.016367138093596967,2.9370456548784425,-2.322778804089259,0.37631237198261697,-0.38242840524926425,1.5371485632979602,-1.4289752964885551,-0.21460863651032072,2.476362718198995,-0.12359730196853358,-0.17801939264792577,-0.0697175034169823,-0.08761798539547284,1.1750660998212703,-1.2462201842490934,-0.5753511440847348,-0.7552931886481278,1.1028509503603623,-0.8788422456292129,0.6498149999479569,-0.45875103683278273,0.7432963349263024,1.6310438815235109,-0.816695122060931,1.6972419576576543,-0.734987782876194,3.8970922624249527,-0.45875103683278273,-0.8373269556814524,-0.6148026217922726,2.849646985468308,2.0429842610179008,0.8200555833521682,-0.7756790296554901,2.0678507334274334,0.05396445492275118,2.429630217950549,-0.6346410197289641,-0.6148026217922726,2.2513014055146834,0.0013008185617386194,1.8146366269813823,0.8958117073182634,0.2765242843820892,-0.21460863651032072,0.35980406748615534,-0.1598176269326193,-0.2885444250862047 | 3,220 |
Endoplasmic reticulum organization | 18 | 51 | 2.002343 | 0.045248 | Q8N4V1,P57088,O95197,Q6P1A2,Q15629,Q8NFQ8,Q9NQC3,P46379,Q6NUK4,Q15363,Q8N5M9,Q12907,Q9P2W9,Q9BRK0,Q8NHH9,Q96A33,Q15042,Q9NPA0 | Processes and pathways | GO Biological process | msigdb_gobp | 519,672,70,135,40,583,218,74,359,174,571,594,214,447,473,510,708,383 | 837,1310,1133,1221,1884,1373,2277,2570,952,1315,70,2003,74,805,672,706,1495,1980,594,3098,3070,873,708,174,40,1296,1356,1538,2489,359,135,3205,519,571,1913,583,473,510,447,1686,1100,1689,877,1728,383,218,1188,1632,1271,1080,214 | 0.35980406748615534,0.018911776033070288,0.1234049013882804,0.07140704367232885,-0.26996449947284556,-0.016367138093596967,-0.45875103683278273,-0.6346410197289641,0.25971817742088116,0.018911776033070288,2.671311648044078,-0.32589947589414364,2.6486761830833725,0.39277227311778157,0.52274910566409,0.4905340462119068,-0.0697175034169823,-0.3071892340680954,0.6183128656109925,-1.3826434778969552,-1.2686964078222256,0.3266408648453037,0.4905340462119068,1.749692739800018,3.1190583891400703,0.03646617604599439,0.0013008185617386194,-0.08761798539547284,-0.5753511440847348,1.0150119726592919,2.0678507334274334,-3.022956497282696,0.7278212652439908,0.6498149999479569,-0.26996449947284556,0.6340856185045755,0.8047850051193207,0.7432963349263024,0.8504766336813527,-0.1598176269326193,0.1577993598585383,-0.1598176269326193,0.3266408648453037,-0.17801939264792577,0.9705957683905887,1.4964610648684789,0.10612684878694781,-0.12359730196853358,0.05396445492275118,0.17491657237536232,1.523616265744399 | 3,220 |
Chloride transport | 7 | 13 | 2.000951 | 0.045398 | P54105,P51798,Q9UHG3,Q9Y696,P30536,P08183,Q9C0H2 | Processes and pathways | GO Biological process | msigdb_gobp | 224,390,9,173,52,149,317 | 2196,149,52,631,390,224,928,933,1869,317,458,9,173 | -0.42045193619341065,1.9551696478034846,2.9370456548784425,0.570731465647822,0.9557152813913782,1.469183965403333,0.2765242843820892,0.2765242843820892,-0.2514489150329518,1.1173645556010907,0.8352860417348812,3.8876483838268006,1.762736125125094 | 3,220 |
Increased csf lactate | 12 | 54 | 1.990882 | 0.046494 | Q86Y39,P03886,O43676,P00846,O75306,Q7KZN9,P13073,Q96CU9,Q9NPL8,O95831,Q8NI60,Q9Y6M9 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 323,35,4,5,185,365,459,110,308,56,312,219 | 2147,2691,2197,4,1082,953,185,2149,1602,1450,56,2152,1523,5,35,1139,459,1845,3178,3132,1346,1381,2208,959,2673,1896,2727,1706,2545,927,1901,1795,1646,365,2358,323,2521,2392,312,676,2522,110,2761,2560,475,813,1919,978,308,1157,1059,1440,587,219 | -0.4014060235952034,-0.7147620507399399,-0.42045193619341065,4.000152058472825,0.1577993598585383,0.25971817742088116,1.6972419576576543,-0.4014060235952034,-0.12359730196853358,-0.0518758434297274,2.871604565087976,-0.4014060235952034,-0.08761798539547284,4.000152058472825,3.182140780093308,0.1234049013882804,0.8200555833521682,-0.2514489150329518,-2.0760553162811117,-1.5706843015800522,0.0013008185617386194,-0.016367138093596967,-0.42045193619341065,0.25971817742088116,-0.6946152420106493,-0.26996449947284556,-0.734987782876194,-0.17801939264792577,-0.6148026217922726,0.2765242843820892,-0.26996449947284556,-0.21460863651032072,-0.1416770949560075,1.0002438855216862,-0.49733057641843204,1.1028509503603623,-0.5950395587962956,-0.5167270700046545,1.131842665374428,0.52274910566409,-0.5950395587962956,2.2633454759922618,-0.7552931886481278,-0.6148026217922726,0.8047850051193207,0.39277227311778157,-0.26996449947284556,0.25971817742088116,1.1462854884410842,0.1234049013882804,0.19198097023818944,-0.03409254115393349,0.6340856185045755,1.4964610648684789 | 3,220 |
Organic acid transmembrane transporter activity | 8 | 24 | 1.979899 | 0.047715 | P53985,Q9Y619,Q96H78,P30825,Q9H2D1,Q9UBX3,P08183,Q9BQT8 | Functions | GO Molecular function | msigdb_gomf | 98,100,42,172,113,117,149,188 | 2718,950,1038,1342,149,923,172,272,1020,98,1023,2326,1949,42,542,188,113,1878,762,2626,977,117,448,100 | -0.734987782876194,0.25971817742088116,0.19198097023818944,0.0013008185617386194,1.9551696478034846,0.2765242843820892,1.762736125125094,1.2464143567169512,0.2089929449754568,2.3825572878427748,0.2089929449754568,-0.4780054421063545,-0.2885444250862047,3.1190583891400703,0.6967457674248935,1.6840592373762224,2.2392345851924724,-0.2514489150329518,0.4418649480306156,-0.6545554493319645,0.25971817742088116,2.202896581642796,0.8504766336813527,2.3470255521669765 | 3,220 |
Glycoprotein biosynthetic process | 17 | 64 | 1.973751 | 0.04841 | Q86YN1,Q8NCH0,O15118,Q9NRB3,Q10472,Q7LGA3,Q8NBI6,Q96JB2,Q8N4A0,Q8WVQ1,Q9HC07,O14734,Q99805,O60502,Q9BXS4,Q9Y287,O43505 | Processes and pathways | GO Biological process | msigdb_gobp | 121,66,132,249,263,329,397,339,16,275,209,400,112,53,216,153,125 | 400,132,578,125,601,53,982,1375,2001,589,1160,1064,1818,1455,2542,823,1847,656,1384,2987,2125,825,1853,1069,263,1146,2257,830,2175,2556,2824,329,2054,1358,2026,121,16,397,66,275,1177,3175,2431,339,2967,112,761,418,216,2401,1266,1771,598,3049,3013,209,545,249,2495,1961,879,153,2912,2739 | 0.925840291261168,2.0678507334274334,0.6340856185045755,2.0926196356487297,0.6024964515538668,2.9261833560805797,0.24286116834863625,-0.016367138093596967,-0.32589947589414364,0.6183128656109925,0.10612684878694781,0.17491657237536232,-0.23299713672055136,-0.0518758434297274,-0.6148026217922726,0.37631237198261697,-0.2514489150329518,0.5387882806522121,-0.016367138093596967,-1.048383343404092,-0.38242840524926425,0.37631237198261697,-0.2514489150329518,0.17491657237536232,1.2747164985345982,0.1234049013882804,-0.4395667391423701,0.37631237198261697,-0.4014060235952034,-0.6148026217922726,-0.816695122060931,1.0883016389264322,-0.34467570745505544,0.0013008185617386194,-0.32589947589414364,2.154121017404892,3.578537157606604,0.9407968670536033,2.7275612767517217,1.2464143567169512,0.10612684878694781,-2.0494460040865254,-0.5361955620517158,1.0737164085829487,-1.0054619519349215,2.2392345851924724,0.4418649480306156,0.8958117073182634,1.510053820463283,-0.5167270700046545,0.05396445492275118,-0.19628289327204587,0.6183128656109925,-1.1793974892219743,-1.0916744984583173,1.550650874331608,0.6967457674248935,1.3309226575327,-0.5753511440847348,-0.2885444250862047,0.3266408648453037,1.9425238010056298,-0.9206985782314582,-0.734987782876194 | 3,220 |
Organic hydroxy compound biosynthetic process | 20 | 57 | 1.969372 | 0.04891 | P00374,Q6P1A2,Q15392,Q16850,O14734,O15270,Q9H2C2,P54646,P11413,Q15800,Q15125,O15269,Q14739,Q03426,Q9Y4G8,P48449,P16435,Q14534,P05091,P04062 | Processes and pathways | GO Biological process | msigdb_gobp | 128,135,8,139,400,536,166,299,307,57,186,316,195,321,215,89,479,507,503,252 | 3101,400,950,316,536,3102,2811,1039,1929,128,1890,252,503,2896,307,924,479,2574,1606,2504,1380,1490,2543,2119,1787,89,1532,299,2013,2753,321,568,2290,507,195,186,2730,8,2554,57,2555,139,135,2026,3175,2731,2594,2829,2560,166,1268,2034,944,1692,1561,215,2872 | -1.40575437454355,0.925840291261168,0.25971817742088116,1.1173645556010907,0.6967457674248935,-1.40575437454355,-0.816695122060931,0.19198097023818944,-0.2885444250862047,2.08024732306687,-0.26996449947284556,1.3028854311521958,0.7432963349263024,-0.8997273591394968,1.1462854884410842,0.2765242843820892,0.7894740510587488,-0.6346410197289641,-0.12359730196853358,-0.5950395587962956,-0.016367138093596967,-0.0697175034169823,-0.6148026217922726,-0.38242840524926425,-0.21460863651032072,2.476362718198995,-0.08761798539547284,1.1750660998212703,-0.32589947589414364,-0.7552931886481278,1.1028509503603623,0.6498149999479569,-0.45875103683278273,0.7432963349263024,1.6310438815235109,1.6972419576576543,-0.734987782876194,3.8970922624249527,-0.6148026217922726,2.849646985468308,-0.6148026217922726,2.0429842610179008,2.0678507334274334,-0.32589947589414364,-2.0494460040865254,-0.734987782876194,-0.6346410197289641,-0.816695122060931,-0.6148026217922726,1.8146366269813823,0.05396445492275118,-0.32589947589414364,0.2765242843820892,-0.1598176269326193,-0.08761798539547284,1.523616265744399,-0.8580423894893902 | 3,220 |
Joint contracture of the hand | 12 | 47 | 1.968283 | 0.049035 | P16435,Q9Y619,Q15392,P07196,Q9NR77,Q8WVQ1,Q8IZA0,Q9BUB7,P42892,Q9Y2B2,O75844,Q13509 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 479,100,8,490,143,275,145,476,116,575,60,191 | 2108,738,2993,2572,2439,60,1522,2470,2636,490,479,1935,2604,2670,1638,1227,1116,116,1019,805,1322,1021,2422,191,2424,1616,2679,1536,708,8,969,1430,145,1399,275,610,2056,2954,1476,476,2889,898,1880,143,575,1444,100 | -0.38242840524926425,0.45813460865092626,-1.069982220146501,-0.6346410197289641,-0.555736700872356,2.772217490447734,-0.08761798539547284,-0.5753511440847348,-0.6745466175994318,0.7741224625935152,0.7894740510587488,-0.2885444250862047,-0.6545554493319645,-0.6946152420106493,-0.1416770949560075,0.07140704367232885,0.1406289365023446,2.202896581642796,0.2089929449754568,0.39277227311778157,0.018911776033070288,0.2089929449754568,-0.5361955620517158,1.6708482172787353,-0.5361955620517158,-0.12359730196853358,-0.6946152420106493,-0.08761798539547284,0.4905340462119068,3.8970922624249527,0.25971817742088116,-0.03409254115393349,1.9929548607271643,-0.016367138093596967,1.2464143567169512,0.6024964515538668,-0.34467570745505544,-0.9841375547653614,-0.0518758434297274,0.8047850051193207,-0.8788422456292129,0.3099852650743845,-0.2514489150329518,2.018019285747357,0.6498149999479569,-0.03409254115393349,2.3470255521669765 | 3,220 |
Disproportionate short stature | 12 | 28 | 1.966327 | 0.049261 | Q14739,Q15392,Q03164,Q7LGA3,O00116,Q8WVQ1,O75718,Q9UHX1,Q7RTS9,Q14696,Q15125,Q9BV10 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 195,8,136,329,267,275,370,246,23,410,186,418 | 267,1193,601,2860,370,1280,1488,2281,2163,2914,136,410,195,2087,186,8,442,969,329,23,2226,275,2267,812,794,418,944,246 | 1.260582173772455,0.08879436807865256,0.6024964515538668,-0.8580423894893902,0.985438559898124,0.03646617604599439,-0.0697175034169823,-0.45875103683278273,-0.4014060235952034,-0.9417567645751581,2.0554297514585023,0.9108453175982513,1.6310438815235109,-0.3635184931943372,1.6972419576576543,3.8970922624249527,0.8504766336813527,0.25971817742088116,1.0883016389264322,3.489070134940879,-0.42045193619341065,1.2464143567169512,-0.4395667391423701,0.39277227311778157,0.4091841119508032,0.8958117073182634,0.2765242843820892,1.3448923432382656 | 3,220 |
Receptor | 12 | 37 | 1.964196 | 0.049507 | O43731,Q99720,Q14739,O15118,O15173,P30825,Q14108,P24390,Q99523,Q9NS69,O00264,Q8WTV0 | Functions | Protein Atlas Molecular function | protein_atlas_molecular_function | 63,2,195,132,107,172,204,46,276,90,222,94 | 222,3199,132,107,63,1341,515,2635,669,1604,2667,2472,803,2907,772,1743,565,46,172,1142,2986,2616,204,195,2326,2327,94,2455,3175,276,1872,2,90,325,1337,652,2409 | 1.469183965403333,-2.7668742866178606,2.0678507334274334,2.2753668998502135,2.749927184602673,0.0013008185617386194,0.7278212652439908,-0.6745466175994318,0.52274910566409,-0.12359730196853358,-0.6946152420106493,-0.5753511440847348,0.39277227311778157,-0.9206985782314582,0.4255482257460382,-0.19628289327204587,0.6498149999479569,3.0660354910464336,1.762736125125094,0.1234049013882804,-1.048383343404092,-0.6545554493319645,1.564123358690429,1.6310438815235109,-0.4780054421063545,-0.4780054421063545,2.429630217950549,-0.555736700872356,-2.0494460040865254,1.2464143567169512,-0.2514489150329518,4.1747248666380585,2.476362718198995,1.1028509503603623,0.018911776033070288,0.5547822987884946,-0.5167270700046545 | 3,220 |
Cellular response to alcohol | 7 | 12 | 2.687471 | 0.0072 | Q9H4A6,Q13085,O95831,P11802,P14923,P54646,O43823 | Processes and pathways | GO Biological process | msigdb_gobp | 339,106,43,150,217,58,276 | 276,43,730,150,217,1491,2180,457,58,106,1728,339 | 1.0387290260730422,2.2711052333509576,0.4756736149025885,1.5160046188311507,1.235411666593502,0.0524073958753585,-0.3150334241341764,0.7292423977918085,2.075696970411644,1.7121335159523754,-0.06059324339671646,0.926245366678696 | 3,148 |
Cellular response to ketone | 6 | 17 | 2.582234 | 0.009816 | Q9H7B4,Q13085,O95831,P11802,P54646,O43823 | Processes and pathways | GO Biological process | msigdb_gobp | 2,106,43,150,58,276 | 276,43,1760,150,1491,1086,2710,1617,58,106,2691,2611,1728,1014,1993,339,2 | 1.0387290260730422,2.2711052333509576,-0.08885159371397018,1.5160046188311507,0.0524073958753585,0.25002932703480435,-0.7679830080483045,-0.0040863327693441845,2.075696970411644,1.7121335159523754,-0.7396516984460482,-0.6263551796478279,-0.06059324339671646,0.3064617290977878,-0.20191718987144255,0.926245366678696,6.582322118363262 | 3,148 |
ENTH/VHS [IPR008942] | 6 | 12 | 2.334277 | 0.019581 | O14964,Q9Y6I3,Q96P16,O95104,Q9UJY5,Q92783 | Sequence | InterPro Superfamily | interpro_homologous_superfamily | 342,499,606,326,251,219 | 342,1603,326,1921,1627,719,1292,219,606,1794,251,499 | 0.8981141364397107,-0.0040863327693441845,0.926245366678696,-0.1736459985280203,-0.0040863327693441845,0.5038629106327192,0.16535467283387026,1.235411666593502,0.5884085708801937,-0.08885159371397018,1.1511451556179018,0.701083314356878 | 3,148 |
Embryonic stem cell pluripotency pathways | 9 | 11 | 2.249705 | 0.024468 | P61160,P31751,P40763,P35222,Q06124,Q02750,P49841,P28482,P62993 | Processes and pathways | WikiPathways | msigdb_wp | 598,507,198,457,744,630,708,456,315 | 456,507,457,772,198,2078,708,598,315,630,744 | 0.7292423977918085,0.6729203634217007,0.7292423977918085,0.44748065541321097,1.2915671122614276,-0.25846904859620284,0.5038629106327192,0.5884085708801937,0.9543725014166323,0.5602304133899906,0.4756736149025885 | 3,148 |
Regulation of protein modification process | 70 | 284 | 2.240277 | 0.025073 | Q9H7B4,O00165,P67870,P62841,P37198,Q96DY7,Q69YH5,Q15020,P31751,Q9C0C2,P53350,P61927,Q96KB5,Q9BRG1,P19474,Q15149,Q92564,Q32P28,Q9Y376,O43823,Q03164,Q99640,P26358,Q9UHD1,Q13418,Q8WUA2,O96017,Q5HYI8,Q9GZS3,Q9H2P0,Q9NVN8,Q7Z434,P49840,P54646,O95067,Q13610,P31689,P51610,Q53EL6,Q96JM3,P49736,P35222,Q06787,Q96JB5,Q96FW1,Q96SZ6,O95429,P11413,Q9ULX6,P60866,Q6NXT1,Q9H4A3,O00560,Q8N7H5,P14635,P28482,Q12792,O95684,Q8IXJ6,Q96GG9,O14964,Q13546,O43684,O60566,Q14166,Q6PJG6,P04792,Q13526,P51452,Q13043 | Processes and pathways | GO Biological process | msigdb_gobp | 2,500,260,375,372,266,10,12,507,401,508,138,275,154,270,281,550,282,423,276,28,157,277,420,163,37,39,172,444,445,446,437,426,58,308,462,562,568,466,202,566,457,331,605,213,214,84,453,611,460,87,353,590,249,455,456,489,100,228,229,342,238,475,477,115,517,119,379,121,377 | 500,1256,590,1257,1899,342,696,2757,1650,891,3029,475,2890,276,2320,892,477,1428,2398,1082,3087,802,660,2594,1030,1130,701,951,1702,2271,1131,1032,617,308,2595,2965,1316,84,100,2401,39,663,2801,2274,2598,119,2449,1658,1854,664,2072,1762,2912,1433,2833,453,2600,1264,2279,2979,1206,455,2126,1207,1705,1706,270,1376,2177,594,1377,277,2280,1766,1323,456,1497,1379,3101,562,507,623,1442,1091,1768,457,2379,772,372,2335,2574,2078,2454,1618,1272,1144,997,2724,1383,2648,738,566,2789,426,708,1916,1276,2457,121,2981,568,508,1147,58,1445,712,460,2382,2487,1566,3063,138,1622,2140,2515,1447,375,2409,2184,2605,2237,674,260,1050,742,2654,1219,630,28,1220,1776,744,331,2462,489,377,778,1054,2414,2188,1449,2085,1450,917,1003,163,1452,379,238,2039,462,1333,115,1397,920,1106,12,2609,3114,281,2492,1336,3011,2242,1060,2847,2090,2727,282,2344,466,1722,172,1577,10,783,1927,87,638,517,1824,437,2049,1166,1826,1878,1236,1981,228,1342,249,2840,37,1832,550,2467,1063,1297,2388,2657,881,1463,1240,1933,1789,2746,266,213,229,3084,2357,605,202,275,1637,1883,2731,2358,1349,214,1586,1993,2672,1587,157,1299,154,2991,1303,2205,1519,3076,1304,2748,401,444,935,886,1521,1071,445,353,2,1685,446,1645,2437,2855,2888,2501,1022,2058,3015,1356,3018,420,1748,846,2163,1421,1750,1187,611,1691,1895,1253,978,423,2831,2212,1751,981,2063,3089 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| 3,148 |
Peroxisome organization | 7 | 15 | 2.067736 | 0.038665 | P50542,Q9Y5Y5,P33897,Q9GZY8,Q96HA9,Q7Z434,O75381 | Processes and pathways | GO Biological process | msigdb_gobp | 312,341,409,338,8,437,293 | 1366,2756,1607,293,2547,1441,409,538,312,2725,437,8,338,1357,341 | 0.10888778490524506,-0.852993935702393,-0.0040863327693441845,0.9824955102294501,-0.5697243611728654,0.08064926784307387,0.785548853420339,0.644753571697058,0.9543725014166323,-0.7963171603475706,0.7573975866378374,4.490632229896861,0.926245366678696,0.1371229267545559,0.926245366678696 | 3,148 |
Narrow palpebral fissure | 7 | 15 | 2.063361 | 0.039078 | O75648,P26196,O95394,Q9H2P0,Q96DF8,Q9NXH9,Q03164 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 479,505,269,445,321,187,28 | 479,269,505,1662,2026,28,920,576,2293,1295,880,321,2531,445,187 | 0.701083314356878,1.066839469913308,0.6729203634217007,-0.03233815004043155,-0.230191545839671,2.6890788369457934,0.3628800323645735,0.6165829655237384,-0.37161017777005423,0.16535467283387026,0.3910838406584684,0.9543725014166323,-0.541413365564062,0.7573975866378374,1.347704436686564 | 3,148 |
Microtubule anchoring | 7 | 9 | 2.061273 | 0.039277 | O95684,O75122,Q14203,Q7Z460,O75381,Q8IWJ2,Q15154 | Processes and pathways | GO Biological process | msigdb_gobp | 100,591,600,111,293,227,433 | 591,293,100,708,600,433,111,227,2501 | 0.5884085708801937,0.9824955102294501,1.740131647521142,0.5038629106327192,0.5884085708801937,0.7573975866378374,1.6841302204122999,1.2073272397217831,-0.5131053331507195 | 3,148 |
Fetal ultrasound soft marker | 10 | 16 | 2.057916 | 0.039598 | P50542,P40855,Q9Y5Y5,Q12768,Q9Y2B2,Q15125,P26196,P61978,O75381,P21281 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 312,538,341,599,761,38,505,511,293,593 | 293,1704,593,505,538,312,1445,2725,511,744,599,38,1015,761,341,1364 | 0.9824955102294501,-0.06059324339671646,0.5884085708801937,0.6729203634217007,0.644753571697058,0.9543725014166323,0.08064926784307387,-0.7963171603475706,0.6729203634217007,0.4756736149025885,0.5884085708801937,2.3826627818452883,0.3064617290977878,0.4756736149025885,0.926245366678696,0.1371229267545559 | 3,148 |
Regulation of jnk cascade | 6 | 12 | 2.048784 | 0.040483 | P31689,Q53EL6,Q13546,Q969S3,P51452,O00560 | Processes and pathways | GO Biological process | msigdb_gobp | 562,466,238,200,121,590 | 590,899,562,597,121,1502,238,466,2054,200,2357,1421 | 0.5884085708801937,0.3628800323645735,0.6165829655237384,0.5884085708801937,1.6281083276502526,0.0524073958753585,1.1792383910724251,0.7292423977918085,-0.230191545839671,1.2915671122614276,-0.3999031538685047,0.10888778490524506 | 3,148 |
Armadillo [IPR000225] | 8 | 15 | 2.027172 | 0.042645 | O60684,Q9UH62,O00192,O60716,Q10567,P52306,P35222,P14923 | Sequence | InterPro Repeat | interpro_repeat | 533,759,96,659,745,358,457,217 | 96,1027,533,659,1699,217,457,1814,816,358,1671,745,1975,1290,759 | 1.740131647521142,0.27824727930122994,0.644753571697058,0.5320485183290543,-0.06059324339671646,1.235411666593502,0.7292423977918085,-0.11711318209211659,0.4192840561185819,0.8699788406740077,-0.03233815004043155,0.4756736149025885,-0.20191718987144255,0.16535467283387026,0.4756736149025885 | 3,148 |
Endopeptidase activity | 28 | 57 | 3.870669 | 0.000109 | O43464,P28072,P49720,P20618,Q9BXS4,O43847,P49721,P67812,Q96K76,P28070,P60900,Q99797,Q8TCT8,Q4J6C6,O75844,Q9BYT8,Q10713,Q8TCT9,P48147,Q99436,Q5JRX3,P52888,Q9NZ08,P22695,P28074,Q92905,Q96E52,Q92643 | Functions | GO Molecular function | msigdb_gomf | 503,260,133,138,275,159,32,163,37,177,50,54,194,322,69,487,215,347,220,367,362,361,119,360,242,376,124,508 | 2107,1701,503,159,1299,69,2065,2367,1036,1214,138,360,1072,177,260,242,889,2746,1589,1263,1645,220,133,32,1797,361,2944,2614,50,163,215,1318,2861,1472,523,322,362,1114,1390,194,347,1016,508,376,1234,923,124,37,2009,367,1394,54,902,275,487,119,1365 | -0.44132700120879625,-0.20540847316623317,0.6649333439702259,1.6439389719907391,0.022527332531551376,2.5652503504888915,-0.4173538681027949,-0.6116478542652064,0.17770858414888777,0.06721945624007275,1.7692815441810628,0.9266068390226809,0.1557501687575436,1.553202877356439,1.2176973554481503,1.2746191459726386,0.28648432191911377,-0.9665176304872712,-0.13622316069244658,0.04490947737153897,-0.15920642504678456,1.3498751782655338,1.804742035797999,3.1290816434117823,-0.2519294648126461,0.9266068390226809,-1.4550577626394943,-0.8119817547252068,2.8202460802749503,1.6077673117097622,1.3685769357877944,0.022527332531551376,-1.1787698895200653,-0.06773581807620718,0.6444173395953164,1.005321354697109,0.9266068390226809,0.13372264733385414,-0.022456018591835984,1.4798666078148721,0.9660662342487973,0.19959848010973788,0.6649333439702259,0.9067996292104508,0.06721945624007275,0.2648627970741298,1.8752060118084188,3.0528553449126603,-0.36966757047407667,0.9266068390226809,-0.022456018591835984,2.725483103215559,0.28648432191911377,1.179516459667705,0.7057948318332095,1.8927280853424016,7.238315672777529e-05 | 3,040 |
Mitochondrial transmembrane transport | 15 | 49 | 3.838477 | 0.000124 | Q9H2D1,O60830,O95563,O43772,Q99595,Q9H4I9,P00846,P23786,Q9BSK2,O75964,Q8IYU8,Q9BPX6,P21796,Q9Y619,O14925 | Processes and pathways | GO Biological process | msigdb_gobp | 66,5,167,40,7,200,73,106,77,79,48,51,211,185,282 | 282,471,40,5,1499,1299,1096,1666,79,1031,1032,167,381,786,73,1170,694,2763,789,580,211,106,913,2556,791,2921,1039,2268,741,1412,696,463,803,289,48,2209,1808,7,51,77,66,200,637,1157,704,557,1815,1365,185 | 1.1411462025905137,0.7057948318332095,2.9914106766594255,5.283619928591475,-0.09048855958396525,0.022527332531551376,0.13372264733385414,-0.18226795279044486,2.4020229552889067,0.17770858414888777,0.17770858414888777,1.5896203443681522,0.8869402512163685,0.3723187418842105,2.5328492892945635,0.0894578986082535,0.4571356471709892,-0.9926509483185962,0.3723187418842105,0.5617747326313666,1.3872343728517897,2.014354642413987,0.2648627970741298,-0.7613038169053663,0.3723187418842105,-1.3708103994508807,0.17770858414888777,-0.5381064762809528,0.41485233449395625,-0.04505853001654639,0.4571356471709892,0.7261411670729521,0.3723187418842105,1.1025840074529036,2.867252154746337,-0.4895375675230639,-0.2519294648126461,4.44501076876835,2.8202460802749503,2.4676830441944553,2.5975316656659477,1.4429435920810105,0.5200999892947062,0.11162542503352747,0.4571356471709892,0.6032126407743291,-0.2519294648126461,7.238315672777529e-05,1.5166189935414305 | 3,040 |
SLC superfamily of solute carriers | 24 | 44 | 3.772949 | 0.000161 | Q6NT16,P41440,O43826,Q9HC07,Q9Y6C9,Q9UJS0,O95563,O43772,Q6N075,Q9NZJ7,O00400,Q9Y619,Q70HW3,Q9H2D1,Q8IXU6,Q9BSK2,Q02978,P12236,O43808,Q99808,Q9H0U3,P53985,Q9UBX3,Q9H936 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 273,146,151,156,160,557,167,40,548,174,53,185,63,66,453,77,583,580,461,90,349,95,232,637 | 53,40,461,151,1096,1032,167,1170,1793,912,789,580,146,2268,95,1380,696,583,1883,548,273,972,2001,1848,63,1572,453,2424,1886,629,90,77,349,66,2941,637,1157,156,1582,174,232,557,185,160 | 2.725483103215559,2.9914106766594255,0.7261411670729521,1.6978944756633867,0.13372264733385414,0.17770858414888777,1.5896203443681522,0.0894578986082535,-0.2519294648126461,0.2648627970741298,0.3723187418842105,0.5617747326313666,1.715800083261279,-0.5381064762809528,2.185089936053244,-0.022456018591835984,0.4571356471709892,0.5617747326313666,-0.2987754614191971,0.6032126407743291,1.179516459667705,0.22142043515709942,-0.36966757047407667,-0.2753114513174612,2.62969443108639,-0.11331744141047409,0.7464317890494901,-0.6363489276465712,-0.2987754614191971,0.5200999892947062,2.269179628829763,2.4676830441944553,0.9660662342487973,2.5975316656659477,-1.4268406552009354,0.5200999892947062,0.11162542503352747,1.679949247910155,-0.11331744141047409,1.571432284289661,1.3123375484934685,0.6032126407743291,1.5166189935414305,1.6258734378927253 | 3,040 |
Intrinsic component of mitochondrial membrane | 23 | 51 | 3.751228 | 0.000176 | Q13505,O60830,Q99595,Q8TB36,Q8N8Q8,O14925,Q6P4A7,P57105,O95563,Q9BPX6,Q9H3K2,Q9BUR5,O75880,O75431,Q15070,Q9H4I9,Q9BWH2,Q5XKP0,Q15388,Q9Y2R0,Q9GZY8,Q9Y512,Q9UG56 | Localization | GO Cellular component | msigdb_gocc | 3,5,7,391,264,282,289,38,167,51,572,184,559,558,196,200,598,466,463,86,368,248,247 | 282,1209,5,558,559,1031,1211,167,786,789,1504,2845,1715,1039,38,696,3,196,463,1720,1044,587,466,289,2448,1771,1611,1084,264,2209,391,7,51,662,184,598,368,572,200,1157,1021,1582,2217,810,811,247,682,86,1365,248,837 | 1.1411462025905137,0.06721945624007275,5.283619928591475,0.582523062344913,0.582523062344913,0.17770858414888777,0.06721945624007275,1.5896203443681522,0.3723187418842105,0.3723187418842105,-0.09048855958396525,-1.151830630256655,-0.20540847316623317,0.17770858414888777,3.037533168359685,0.4571356471709892,5.7379702431047095,1.4614265634176216,0.7261411670729521,-0.20540847316623317,0.17770858414888777,0.5617747326313666,0.7261411670729521,1.1025840074529036,-0.6611452764022983,-0.22862872657474756,-0.13622316069244658,0.1557501687575436,1.1986304188795078,-0.4895375675230639,0.867028329570998,4.44501076876835,2.8202460802749503,0.4991726460209864,1.5166189935414305,0.5617747326313666,0.9266068390226809,0.582523062344913,1.4429435920810105,0.11162542503352747,0.19959848010973788,-0.11331744141047409,-0.4895375675230639,0.3723187418842105,0.3723187418842105,1.2746191459726386,0.4781846919533493,2.352447611616457,7.238315672777529e-05,1.2746191459726386,0.3509568225038281 | 3,040 |
Glycerolipid biosynthetic process | 21 | 49 | 3.697965 | 0.000217 | Q8NF37,Q8NCC3,Q9NPH0,Q969N2,Q8WTV0,Q9NUQ2,Q96PE3,Q96S52,P35790,Q6P1A2,Q96N66,Q8TBX8,Q08AM6,O14735,Q9BTU6,Q10713,Q86UL3,Q9HBU6,Q9UG56,Q7L5N7,Q92643 | Processes and pathways | GO Biological process | msigdb_gobp | 659,17,18,406,22,153,35,438,435,61,197,594,451,446,468,215,483,96,247,628,508 | 1131,446,1701,1634,1548,1212,1739,1825,1214,1075,435,716,2265,943,2505,451,215,1386,655,1609,61,628,483,17,1052,659,594,22,1015,1810,1325,508,406,197,35,438,2011,1857,468,1436,2096,96,755,18,1285,153,1628,907,247 | 0.11162542503352747,0.7464317890494901,-0.20540847316623317,-0.15920642504678456,-0.11331744141047409,0.06721945624007275,-0.22862872657474756,-0.2753114513174612,0.06721945624007275,0.1557501687575436,0.7666671108145032,0.43602502551870426,-0.5381064762809528,0.24317501987691698,-0.7110278429358069,0.7464317890494901,1.3685769357877944,-0.022456018591835984,0.4991726460209864,-0.13622316069244658,2.661739823625172,0.5200999892947062,0.7057948318332095,3.6025751739028236,0.17770858414888777,0.4991726460209864,0.5617747326313666,3.4278200746104854,0.19959848010973788,-0.2519294648126461,0.022527332531551376,0.6649333439702259,0.8270453312183077,1.4614265634176216,3.0834224304076256,0.7666671108145032,-0.36966757047407667,-0.2753114513174612,0.7261411670729521,-0.04505853001654639,-0.4173538681027949,2.185089936053244,0.41485233449395625,3.573673225714372,0.04490947737153897,1.6978944756633867,-0.13622316069244658,0.28648432191911377,1.2746191459726386 | 3,040 |
Protein targeting to mitochondrion | 20 | 46 | 3.53221 | 0.000412 | O60830,P55786,Q99595,Q8TB36,Q9NS69,O14925,O14737,Q99797,O95429,Q9Y584,Q8N4H5,Q15388,Q10713,P62072,O43615,O60220,Q9GZY8,Q9Y512,Q5JRX3,O95831 | Processes and pathways | GO Biological process | msigdb_gobp | 5,6,7,391,14,282,180,54,432,62,199,463,215,91,471,228,368,248,362,381 | 2105,180,282,503,471,228,5,1298,1299,1031,1211,432,641,381,786,2066,2763,1407,2781,2305,1223,6,91,1182,215,463,2822,803,587,362,2389,199,391,7,54,368,704,14,906,2542,1486,3002,248,62,758,2406 | -0.44132700120879625,1.5349318668753111,1.1411462025905137,0.6649333439702259,0.7057948318332095,1.3123375484934685,5.283619928591475,0.022527332531551376,0.022527332531551376,0.17770858414888777,0.06721945624007275,0.7666671108145032,0.4991726460209864,0.8869402512163685,0.3723187418842105,-0.4173538681027949,-0.9926509483185962,-0.04505853001654639,-1.0188953886833905,-0.5625275930863287,0.06721945624007275,5.13606374568797,2.235643591481525,0.0894578986082535,1.3685769357877944,0.7261411670729521,-1.071722841162979,0.3723187418842105,0.5617747326313666,0.9266068390226809,-0.6116478542652064,1.4429435920810105,0.867028329570998,4.44501076876835,2.725483103215559,0.9266068390226809,0.4571356471709892,3.703045056762135,0.28648432191911377,-0.7361161262584145,-0.06773581807620718,-1.8653737098684169,1.2746191459726386,2.661739823625172,0.41485233449395625,-0.6116478542652064 | 3,040 |
Transporter complex | 20 | 54 | 3.502752 | 0.00046 | P62942,O43676,Q86Y39,P03886,Q8N2K0,Q8IYU8,Q9BPX6,O75381,O96000,O75306,O14949,P0DP25,Q9UDW1,Q9H4I9,Q86WC4,P62072,O60220,Q96CU9,Q8TDW0,O75438 | Localization | GO Cellular component | msigdb_gocc | 130,269,164,47,304,48,51,181,311,57,190,319,71,200,337,91,228,108,236,240 | 2519,1028,190,269,228,1450,57,181,240,785,473,2550,311,47,1169,2257,319,1640,1709,360,2911,647,1987,477,847,1179,91,130,584,1419,2657,1354,337,164,48,304,702,2209,236,108,1616,1618,51,1241,200,1438,906,71,886,1732,758,2406,1205,2844 | -0.7361161262584145,0.17770858414888777,1.4798666078148721,1.179516459667705,1.3123375484934685,-0.06773581807620718,2.67771886764343,1.5349318668753111,1.2746191459726386,0.3723187418842105,0.7057948318332095,-0.7613038169053663,1.0248732054561662,2.929545586146746,0.0894578986082535,-0.5381064762809528,1.005321354697109,-0.15920642504678456,-0.20540847316623317,0.9266068390226809,-1.3429937902950162,0.4991726460209864,-0.36966757047407667,0.7057948318332095,0.32953079791525924,0.0894578986082535,2.235643591481525,1.8400495980357443,0.5617747326313666,-0.04505853001654639,-0.8374742177649565,7.238315672777529e-05,0.9857191490793755,1.6077673117097622,2.867252154746337,1.063827239756187,0.4571356471709892,-0.4895375675230639,1.2935010918758008,1.9797856725780703,-0.13622316069244658,-0.13622316069244658,2.8202460802749503,0.06721945624007275,1.4429435920810105,-0.04505853001654639,0.28648432191911377,2.5652503504888915,0.30804014209060904,-0.20540847316623317,0.41485233449395625,-0.6116478542652064,0.0894578986082535,-1.1250106483577362 | 3,040 |
Phospholipid metabolism | 22 | 49 | 3.499543 | 0.000466 | Q9NP80,Q8NCC3,Q9NPH0,Q9NUQ2,P43304,Q8IV08,Q96PE3,P35790,Q6P1A2,Q9NQZ5,Q96N66,Q8TBX8,Q08AM6,O14735,Q9BTU6,P40939,Q10713,Q53H12,Q86UL3,Q9HBU6,Q9UG56,Q7L5N7 | Processes and pathways | Reactome Pathways | msigdb_reactome | 134,17,18,153,532,291,35,435,61,65,197,594,451,446,468,212,215,587,483,96,247,628 | 1131,446,2108,1212,1825,1407,2745,435,212,716,532,2265,1457,2585,768,1349,2505,451,215,1386,587,61,628,483,291,1047,17,1052,659,594,1015,1325,197,35,1331,2011,902,1857,468,2317,96,755,134,18,65,1285,153,907,247 | 0.11162542503352747,0.7464317890494901,-0.44132700120879625,0.06721945624007275,-0.2753114513174612,-0.04505853001654639,-0.9665176304872712,0.7666671108145032,1.3872343728517897,0.43602502551870426,0.6238439182752883,-0.5381064762809528,-0.06773581807620718,-0.7865919937038053,0.39361707513132105,7.238315672777529e-05,-0.7110278429358069,0.7464317890494901,1.3685769357877944,-0.022456018591835984,0.5617747326313666,2.661739823625172,0.5200999892947062,0.7057948318332095,1.1025840074529036,0.17770858414888777,3.6025751739028236,0.17770858414888777,0.4991726460209864,0.5617747326313666,0.19959848010973788,0.022527332531551376,1.4614265634176216,3.0834224304076256,0.022527332531551376,-0.36966757047407667,0.28648432191911377,-0.2753114513174612,0.7261411670729521,-0.5625275930863287,2.185089936053244,0.41485233449395625,1.804742035797999,3.573673225714372,2.6136277930918457,0.04490947737153897,1.6978944756633867,0.28648432191911377,1.2746191459726386 | 3,040 |
Glycerophospholipid biosynthetic process | 19 | 45 | 3.485 | 0.000492 | Q8NF37,Q9NPH0,Q969N2,Q9NUQ2,Q96PE3,Q96S52,P35790,Q6P1A2,Q96N66,Q8TBX8,Q08AM6,O14735,Q9BTU6,Q10713,Q86UL3,Q9HBU6,Q9UG56,Q7L5N7,Q92643 | Processes and pathways | GO Biological process | msigdb_gobp | 659,18,406,153,35,438,435,61,197,594,451,446,468,215,483,96,247,628,508 | 1131,446,1701,1634,1548,1212,1739,1825,1214,435,716,2265,943,2505,451,215,1386,655,1609,61,628,483,1052,659,594,1015,1810,508,406,197,35,438,2011,1857,468,1436,2096,96,755,18,1285,153,1628,907,247 | 0.11162542503352747,0.7464317890494901,-0.20540847316623317,-0.15920642504678456,-0.11331744141047409,0.06721945624007275,-0.22862872657474756,-0.2753114513174612,0.06721945624007275,0.7666671108145032,0.43602502551870426,-0.5381064762809528,0.24317501987691698,-0.7110278429358069,0.7464317890494901,1.3685769357877944,-0.022456018591835984,0.4991726460209864,-0.13622316069244658,2.661739823625172,0.5200999892947062,0.7057948318332095,0.17770858414888777,0.4991726460209864,0.5617747326313666,0.19959848010973788,-0.2519294648126461,0.6649333439702259,0.8270453312183077,1.4614265634176216,3.0834224304076256,0.7666671108145032,-0.36966757047407667,-0.2753114513174612,0.7261411670729521,-0.04505853001654639,-0.4173538681027949,2.185089936053244,0.41485233449395625,3.573673225714372,0.04490947737153897,1.6978944756633867,-0.13622316069244658,0.28648432191911377,1.2746191459726386 | 3,040 |
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