term
stringlengths
2
121
overlap
int64
6
281
setsize
int64
7
499
score
float64
1.96
10.6
pval
float64
0
0.05
edge
stringlengths
41
1.97k
type
stringclasses
5 values
subtype
stringclasses
24 values
subtype_key
stringclasses
24 values
edge_idxs
stringlengths
11
1.17k
ann_idxs
stringlengths
19
2.31k
ann_vals
stringlengths
124
9.94k
sig_size
int64
2.2k
3.73k
Anion transmembrane transporter activity
22
42
3.408912
0.000652
Q9Y277,P41440,O43826,Q9UJS0,O43681,O95563,Q6N075,O00400,Q9Y619,Q9H2D1,P45880,Q02978,P21796,P12236,O43808,Q99808,P53985,P51798,Q9UBX3,Q8TDW0,Q9H936,Q14728
Functions
GO Molecular function
msigdb_gomf
394,146,151,557,545,167,548,53,185,66,192,583,211,580,461,90,95,477,232,236,637,245
2519,53,545,461,151,1096,167,1170,1793,2111,912,789,580,211,146,192,1596,477,2268,95,1380,583,245,1883,548,972,2001,2424,629,236,1616,90,1241,66,637,1157,1582,232,557,394,185,1205
-0.7361161262584145,2.725483103215559,0.6032126407743291,0.7261411670729521,1.6978944756633867,0.13372264733385414,1.5896203443681522,0.0894578986082535,-0.2519294648126461,-0.44132700120879625,0.2648627970741298,0.3723187418842105,0.5617747326313666,1.3872343728517897,1.715800083261279,1.4798666078148721,-0.13622316069244658,0.7057948318332095,-0.5381064762809528,2.185089936053244,-0.022456018591835984,0.5617747326313666,1.2746191459726386,-0.2987754614191971,0.6032126407743291,0.22142043515709942,-0.36966757047407667,-0.6363489276465712,0.5200999892947062,1.2935010918758008,-0.13622316069244658,2.269179628829763,0.06721945624007275,2.5975316656659477,0.5200999892947062,0.11162542503352747,-0.11331744141047409,1.3123375484934685,0.6032126407743291,0.867028329570998,1.5166189935414305,0.0894578986082535
3,040
Metallopeptidase activity
14
44
3.261308
0.001109
P36551,O75844,P55786,P09960,P53582,Q5JRX3,P52888,Q9NZ08,P22695,Q99797,Q10713,O95630,Q96E52,O43847
Functions
GO Molecular function
msigdb_gomf
288,69,6,259,107,362,361,119,360,54,215,26,124,159
1367,1293,784,159,1299,69,2948,26,2925,259,2032,1036,1708,360,2673,288,1263,2470,1000,361,107,6,215,362,1847,748,774,376,661,1811,124,2536,2009,54,902,487,1244,1198,862,1726,1482,119,501,1365
-0.022456018591835984,0.022527332531551376,0.3723187418842105,1.6439389719907391,0.022527332531551376,2.5652503504888915,-1.483411892468181,3.294580100112679,-1.3987587837144049,1.2176973554481503,-0.3934676753169731,0.17770858414888777,-0.20540847316623317,0.9266068390226809,-0.8630705208373466,1.1025840074529036,0.04490947737153897,-0.6860379068899511,0.19959848010973788,0.9266068390226809,2.014354642413987,5.13606374568797,1.3685769357877944,0.9266068390226809,-0.2753114513174612,0.41485233449395625,0.39361707513132105,0.9067996292104508,0.4991726460209864,-0.2519294648126461,1.8752060118084188,-0.7361161262584145,-0.36966757047407667,2.725483103215559,0.28648432191911377,0.7057948318332095,0.06721945624007275,0.0894578986082535,0.32953079791525924,-0.20540847316623317,-0.06773581807620718,1.8927280853424016,0.6853923652184316,7.238315672777529e-05
3,040
Anion transport
32
65
3.217599
0.001293
O60831,Q9Y277,Q9NP80,Q15907,P41440,O43826,Q9UJS0,O43681,O95563,Q6N075,Q9UHG3,Q9Y4C2,Q9NZJ7,O00400,Q9Y619,Q9H2D1,P45880,Q86WC4,Q02978,P21796,P12236,O43808,Q99808,P53985,P51798,P54105,Q9UBX3,Q8TDW0,Q9H936,Q8TB61,Q14728,P08183
Processes and pathways
GO Biological process
msigdb_gobp
504,394,134,522,146,151,557,545,167,548,42,577,174,53,185,66,192,337,583,211,580,461,90,95,477,352,232,236,637,629,245,255
2519,53,545,461,151,1297,504,1096,1500,167,787,1170,1826,1341,255,1793,2111,912,789,580,763,2974,211,622,146,192,1596,477,2268,95,352,1380,696,583,1384,245,853,1080,1883,522,548,972,2001,1572,337,2424,629,236,1616,90,1241,2904,66,637,1157,1582,134,174,232,42,557,394,577,185,1205
-0.7361161262584145,2.725483103215559,0.6032126407743291,0.7261411670729521,1.6978944756633867,0.022527332531551376,0.6649333439702259,0.13372264733385414,-0.09048855958396525,1.5896203443681522,0.3723187418842105,0.0894578986082535,-0.2753114513174612,7.238315672777529e-05,1.2367175827335657,-0.2519294648126461,-0.44132700120879625,0.2648627970741298,0.3723187418842105,0.5617747326313666,0.39361707513132105,-1.6273031895761814,1.3872343728517897,0.5200999892947062,1.715800083261279,1.4798666078148721,-0.13622316069244658,0.7057948318332095,-0.5381064762809528,2.185089936053244,0.9463622517624058,-0.022456018591835984,0.4571356471709892,0.5617747326313666,-0.022456018591835984,1.2746191459726386,0.32953079791525924,0.1557501687575436,-0.2987754614191971,0.6444173395953164,0.6032126407743291,0.22142043515709942,-0.36966757047407667,-0.11331744141047409,0.9857191490793755,-0.6363489276465712,0.5200999892947062,1.2935010918758008,-0.13622316069244658,2.269179628829763,0.06721945624007275,-1.2877492256217191,2.5975316656659477,0.5200999892947062,0.11162542503352747,-0.11331744141047409,1.804742035797999,1.571432284289661,1.3123375484934685,2.9914106766594255,0.6032126407743291,0.867028329570998,0.582523062344913,1.5166189935414305,0.0894578986082535
3,040
transporter
27
61
3.167115
0.00154
Q12769,O60830,Q99595,Q8N8Q8,Q9NR77,Q8N1F7,P41440,Q92544,Q9C0E2,O43681,O43772,Q9Y619,Q9Y584,Q96P70,Q9H2D1,Q567V2,Q15070,O00410,P52292,Q99808,P62072,P53985,P54105,O43615,Q8NFH4,Q92973,Q9HD45
Functions
Panther Protein class
panther_protein_class
128,5,7,264,11,399,146,540,418,545,40,185,62,457,66,70,196,445,332,90,91,95,352,471,235,364,127
445,1162,2906,960,841,471,545,40,1498,5,692,870,2438,792,146,1457,2935,332,2527,939,2268,95,352,849,718,850,91,128,1685,196,70,548,1848,1148,399,2424,264,235,750,751,540,364,1192,457,724,7,977,90,2013,418,66,2941,778,127,11,929,865,1815,62,2991,185
0.7464317890494901,0.0894578986082535,-1.3153072796901228,0.22142043515709942,0.32953079791525924,0.7057948318332095,0.6032126407743291,2.9914106766594255,-0.09048855958396525,5.283619928591475,0.4571356471709892,0.30804014209060904,-0.6611452764022983,0.3723187418842105,1.715800083261279,-0.06773581807620718,-1.4268406552009354,0.9857191490793755,-0.7361161262584145,0.24317501987691698,-0.5381064762809528,2.185089936053244,0.9463622517624058,0.32953079791525924,0.43602502551870426,0.32953079791525924,2.235643591481525,1.8576465884962547,-0.18226795279044486,1.4614265634176216,2.5652503504888915,0.6032126407743291,-0.2753114513174612,0.11162542503352747,0.8470634843734169,-0.6363489276465712,1.1986304188795078,1.2935010918758008,0.41485233449395625,0.41485233449395625,0.6238439182752883,0.9266068390226809,0.0894578986082535,0.7464317890494901,0.43602502551870426,4.44501076876835,0.22142043515709942,2.269179628829763,-0.36966757047407667,0.8069734811215312,2.5975316656659477,-1.4268406552009354,0.39361707513132105,1.8752060118084188,3.9148541626840703,0.2648627970741298,0.32953079791525924,-0.2519294648126461,2.661739823625172,-1.7450800407293028,1.5166189935414305
3,040
Inner mitochondrial membrane protein complex
22
75
3.139713
0.001691
Q13505,O60830,Q99595,P14406,O43676,O14925,Q86Y39,P03886,Q8IYU8,Q9BPX6,Q9BUR5,O75306,Q9Y584,O14949,Q9UDW1,Q9H4I9,P00846,O75964,P62072,Q96CU9,Q9Y512,O75438
Localization
GO Cellular component
msigdb_gocc
3,5,7,19,269,282,164,47,48,51,184,57,62,190,71,200,73,79,91,108,248,240
1028,1132,282,190,269,5,1450,57,558,240,785,1666,79,473,2550,311,1033,73,47,694,2257,2919,580,762,19,1640,1709,1174,1551,360,913,2556,2911,2647,647,2302,791,2845,2921,1987,847,741,940,1412,91,3,2657,1354,1044,803,587,466,2448,164,48,2209,108,1193,7,725,51,184,200,704,810,1438,811,906,71,886,1732,1365,248,62,2844
0.17770858414888777,0.11162542503352747,1.1411462025905137,1.4798666078148721,1.179516459667705,5.283619928591475,-0.06773581807620718,2.67771886764343,0.582523062344913,1.2746191459726386,0.3723187418842105,-0.18226795279044486,2.4020229552889067,0.7057948318332095,-0.7613038169053663,1.0248732054561662,0.17770858414888777,2.5328492892945635,2.929545586146746,0.4571356471709892,-0.5381064762809528,-1.3708103994508807,0.5617747326313666,0.39361707513132105,3.5010292750882246,-0.15920642504678456,-0.20540847316623317,0.0894578986082535,-0.11331744141047409,0.9266068390226809,0.2648627970741298,-0.7613038169053663,-1.3429937902950162,-0.8374742177649565,0.4991726460209864,-0.5625275930863287,0.3723187418842105,-1.151830630256655,-1.3708103994508807,-0.36966757047407667,0.32953079791525924,0.41485233449395625,0.24317501987691698,-0.04505853001654639,2.235643591481525,5.7379702431047095,-0.8374742177649565,7.238315672777529e-05,0.17770858414888777,0.3723187418842105,0.5617747326313666,0.7261411670729521,-0.6611452764022983,1.6077673117097622,2.867252154746337,-0.4895375675230639,1.9797856725780703,0.0894578986082535,4.44501076876835,0.43602502551870426,2.8202460802749503,1.5166189935414305,1.4429435920810105,0.4571356471709892,0.3723187418842105,-0.04505853001654639,0.3723187418842105,0.28648432191911377,2.5652503504888915,0.30804014209060904,-0.20540847316623317,7.238315672777529e-05,1.2746191459726386,2.661739823625172,-1.1250106483577362
3,040
Glycerophospholipid metabolic process
26
61
3.125154
0.001777
Q8NF37,Q9NP80,P19174,Q8NCC3,Q9NPH0,Q8WTV0,Q969N2,Q9NUQ2,Q96PE3,Q96S52,Q8N2K0,P35790,Q6P1A2,Q96N66,Q8TBX8,Q08AM6,O14735,Q9BTU6,P40939,Q10713,Q86UL3,Q9HBU6,Q9UG56,Q7L5N7,Q9NXE4,Q92643
Processes and pathways
GO Biological process
msigdb_gobp
659,134,519,17,18,22,406,153,35,438,304,435,61,197,594,451,446,468,212,215,483,96,247,628,378,508
1901,1131,446,1701,1634,1548,1212,1739,1825,1214,519,935,435,212,716,2227,2265,2981,943,2505,451,215,1386,655,1609,61,628,483,1047,304,17,1052,659,594,22,1015,1810,1325,508,406,197,35,438,2011,725,1857,468,1436,2317,2096,96,755,134,18,1285,153,1628,378,907,247,1815
-0.32232228259890044,0.11162542503352747,0.7464317890494901,-0.20540847316623317,-0.15920642504678456,-0.11331744141047409,0.06721945624007275,-0.22862872657474756,-0.2753114513174612,0.06721945624007275,0.6444173395953164,0.24317501987691698,0.7666671108145032,1.3872343728517897,0.43602502551870426,-0.5137767760722269,-0.5381064762809528,-1.6565192297626519,0.24317501987691698,-0.7110278429358069,0.7464317890494901,1.3685769357877944,-0.022456018591835984,0.4991726460209864,-0.13622316069244658,2.661739823625172,0.5200999892947062,0.7057948318332095,0.17770858414888777,1.063827239756187,3.6025751739028236,0.17770858414888777,0.4991726460209864,0.5617747326313666,3.4278200746104854,0.19959848010973788,-0.2519294648126461,0.022527332531551376,0.6649333439702259,0.8270453312183077,1.4614265634176216,3.0834224304076256,0.7666671108145032,-0.36966757047407667,0.43602502551870426,-0.2753114513174612,0.7261411670729521,-0.04505853001654639,-0.5625275930863287,-0.4173538681027949,2.185089936053244,0.41485233449395625,1.804742035797999,3.573673225714372,0.04490947737153897,1.6978944756633867,-0.13622316069244658,0.9067996292104508,0.28648432191911377,1.2746191459726386,-0.2519294648126461
3,040
Anion transmembrane transport
22
38
3.088168
0.002014
O60831,Q9Y277,P41440,O43826,Q9UJS0,O95563,Q9UHG3,Q9Y4C2,Q9Y619,P45880,Q9H2D1,Q02978,P21796,P12236,O43808,P53985,P51798,Q9UBX3,Q8TDW0,Q9H936,Q14728,P08183
Processes and pathways
GO Biological process
msigdb_gobp
504,394,146,151,557,167,42,577,185,192,66,583,211,580,461,95,477,232,236,637,245,255
461,151,504,1096,1500,167,1170,1826,255,1793,789,580,211,146,192,1596,477,2268,95,1380,696,583,245,853,1883,2424,629,236,66,637,1157,1582,232,42,557,394,577,185
0.7261411670729521,1.6978944756633867,0.6649333439702259,0.13372264733385414,-0.09048855958396525,1.5896203443681522,0.0894578986082535,-0.2753114513174612,1.2367175827335657,-0.2519294648126461,0.3723187418842105,0.5617747326313666,1.3872343728517897,1.715800083261279,1.4798666078148721,-0.13622316069244658,0.7057948318332095,-0.5381064762809528,2.185089936053244,-0.022456018591835984,0.4571356471709892,0.5617747326313666,1.2746191459726386,0.32953079791525924,-0.2987754614191971,-0.6363489276465712,0.5200999892947062,1.2935010918758008,2.5975316656659477,0.5200999892947062,0.11162542503352747,-0.11331744141047409,1.3123375484934685,2.9914106766594255,0.6032126407743291,0.867028329570998,0.582523062344913,1.5166189935414305
3,040
Mitochondrial respiratory chain complex assembly
20
40
3.087714
0.002017
Q8N8Q8,O43676,Q86Y39,Q9H061,P03886,O96000,O75306,Q96I36,Q9BSH4,Q15070,Q9BSK2,Q9Y2R0,Q9H845,Q69YU5,Q6DKK2,Q96CU9,Q9Y512,O75438,Q96E52,O95831
Processes and pathways
GO Biological process
msigdb_gobp
264,269,164,41,47,311,57,316,325,196,77,86,488,216,482,108,248,240,124,381
269,1209,1450,57,240,785,559,473,2550,381,311,47,2911,847,2202,196,2657,1354,216,482,164,1049,264,108,124,316,978,325,77,2632,41,488,1438,1483,906,886,86,1732,248,2844
1.179516459667705,0.06721945624007275,-0.06773581807620718,2.67771886764343,1.2746191459726386,0.3723187418842105,0.582523062344913,0.7057948318332095,-0.7613038169053663,0.8869402512163685,1.0248732054561662,2.929545586146746,-1.3429937902950162,0.32953079791525924,-0.4895375675230639,1.4614265634176216,-0.8374742177649565,7.238315672777529e-05,1.3685769357877944,0.7057948318332095,1.6077673117097622,0.17770858414888777,1.1986304188795078,1.9797856725780703,1.8752060118084188,1.0248732054561662,0.22142043515709942,1.005321354697109,2.4676830441944553,-0.8119817547252068,2.9914106766594255,0.7057948318332095,-0.04505853001654639,-0.06773581807620718,0.28648432191911377,0.30804014209060904,2.352447611616457,-0.20540847316623317,1.2746191459726386,-1.1250106483577362
3,040
Protein localization to mitochondrion
25
59
3.073897
0.002113
O60830,P55786,Q99595,Q8TB36,Q8N8Q8,Q9NS69,O14925,Q9Y6C9,O14737,Q99797,O95429,Q9Y584,P0DP25,Q15070,Q8N4H5,Q15388,Q10713,P62072,O43615,O60220,Q9GZY8,Q9Y512,Q5JRX3,O00429,O95831
Processes and pathways
GO Biological process
msigdb_gobp
5,6,7,391,264,14,282,160,180,54,432,62,319,196,199,463,215,91,471,228,368,248,362,489,381
2105,1631,489,180,282,503,471,228,5,1298,1299,1031,1211,432,641,381,786,2066,319,2763,2331,1980,1407,2993,2674,2781,2305,1223,1040,6,91,1182,215,196,463,2822,803,587,362,2389,199,264,391,7,54,368,704,14,2019,906,2542,1486,886,3002,248,62,758,2406,160
-0.44132700120879625,-0.15920642504678456,0.6853923652184316,1.5349318668753111,1.1411462025905137,0.6649333439702259,0.7057948318332095,1.3123375484934685,5.283619928591475,0.022527332531551376,0.022527332531551376,0.17770858414888777,0.06721945624007275,0.7666671108145032,0.4991726460209864,0.8869402512163685,0.3723187418842105,-0.4173538681027949,1.005321354697109,-0.9926509483185962,-0.5870410669585505,-0.36966757047407667,-0.04505853001654639,-1.7749118188298865,-0.8630705208373466,-1.0188953886833905,-0.5625275930863287,0.06721945624007275,0.17770858414888777,5.13606374568797,2.235643591481525,0.0894578986082535,1.3685769357877944,1.4614265634176216,0.7261411670729521,-1.071722841162979,0.3723187418842105,0.5617747326313666,0.9266068390226809,-0.6116478542652064,1.4429435920810105,1.1986304188795078,0.867028329570998,4.44501076876835,2.725483103215559,0.9266068390226809,0.4571356471709892,3.703045056762135,-0.36966757047407667,0.28648432191911377,-0.7361161262584145,-0.06773581807620718,0.30804014209060904,-1.8653737098684169,1.2746191459726386,2.661739823625172,0.41485233449395625,-0.6116478542652064,1.6258734378927253
3,040
Organic anion transport
19
43
3.064932
0.002177
O60831,Q9NP80,P41440,Q9UJS0,O95563,Q9NZJ7,O00400,Q9Y619,Q9H2D1,Q02978,P12236,O43808,Q99808,P53985,Q9UBX3,Q8TDW0,Q9H936,Q8TB61,Q14728
Processes and pathways
GO Biological process
msigdb_gobp
504,134,146,557,167,174,53,185,66,583,580,461,90,95,232,236,637,629,245
53,461,504,1096,1500,167,787,1170,1826,1341,1793,912,789,580,763,2974,622,146,2268,95,1380,583,1384,245,853,1080,1883,972,2001,1572,2424,629,236,90,66,637,1157,1582,134,174,232,557,185
2.725483103215559,0.7261411670729521,0.6649333439702259,0.13372264733385414,-0.09048855958396525,1.5896203443681522,0.3723187418842105,0.0894578986082535,-0.2753114513174612,7.238315672777529e-05,-0.2519294648126461,0.2648627970741298,0.3723187418842105,0.5617747326313666,0.39361707513132105,-1.6273031895761814,0.5200999892947062,1.715800083261279,-0.5381064762809528,2.185089936053244,-0.022456018591835984,0.5617747326313666,-0.022456018591835984,1.2746191459726386,0.32953079791525924,0.1557501687575436,-0.2987754614191971,0.22142043515709942,-0.36966757047407667,-0.11331744141047409,-0.6363489276465712,0.5200999892947062,1.2935010918758008,2.269179628829763,2.5975316656659477,0.5200999892947062,0.11162542503352747,-0.11331744141047409,1.804742035797999,1.571432284289661,1.3123375484934685,0.6032126407743291,1.5166189935414305
3,040
Glycerolipid metabolic process
29
67
3.02652
0.002474
Q8NF37,Q9NP80,P19174,Q8NCC3,Q9NPH0,Q8WTV0,Q969N2,Q9NUQ2,Q96PE3,Q8NCG7,Q96S52,Q8N2K0,P35790,Q6P1A2,Q96N66,Q8TBX8,Q08AM6,O14735,Q9UBV2,Q9BTU6,P40939,Q10713,Q53H12,Q86UL3,Q9HBU6,Q9UG56,Q7L5N7,Q9NXE4,Q92643
Processes and pathways
GO Biological process
msigdb_gobp
659,134,519,17,18,22,406,153,35,298,438,304,435,61,197,594,451,446,209,468,212,215,587,483,96,247,628,378,508
1901,1131,446,1701,1634,1548,1212,1739,1825,1214,519,935,1075,435,212,716,2227,2265,1039,2981,943,2505,2507,451,215,1386,587,655,1609,61,628,483,1047,304,17,298,1052,659,594,22,1015,1810,1325,508,406,197,35,438,2011,725,1857,468,1436,2317,2096,96,755,134,18,1285,153,1628,378,907,209,247,1815
-0.32232228259890044,0.11162542503352747,0.7464317890494901,-0.20540847316623317,-0.15920642504678456,-0.11331744141047409,0.06721945624007275,-0.22862872657474756,-0.2753114513174612,0.06721945624007275,0.6444173395953164,0.24317501987691698,0.1557501687575436,0.7666671108145032,1.3872343728517897,0.43602502551870426,-0.5137767760722269,-0.5381064762809528,0.17770858414888777,-1.6565192297626519,0.24317501987691698,-0.7110278429358069,-0.7110278429358069,0.7464317890494901,1.3685769357877944,-0.022456018591835984,0.5617747326313666,0.4991726460209864,-0.13622316069244658,2.661739823625172,0.5200999892947062,0.7057948318332095,0.17770858414888777,1.063827239756187,3.6025751739028236,1.0832301121348886,0.17770858414888777,0.4991726460209864,0.5617747326313666,3.4278200746104854,0.19959848010973788,-0.2519294648126461,0.022527332531551376,0.6649333439702259,0.8270453312183077,1.4614265634176216,3.0834224304076256,0.7666671108145032,-0.36966757047407667,0.43602502551870426,-0.2753114513174612,0.7261411670729521,-0.04505853001654639,-0.5625275930863287,-0.4173538681027949,2.185089936053244,0.41485233449395625,1.804742035797999,3.573673225714372,0.04490947737153897,1.6978944756633867,-0.13622316069244658,0.9067996292104508,0.28648432191911377,1.405847774017092,1.2746191459726386,-0.2519294648126461
3,040
Cation transmembrane transporter activity
14
65
3.018781
0.002538
Q9Y487,Q9UDW1,O43772,P00846,Q7KZN9,O75964,Q93050,O00400,P61421,Q9HD20,Q99808,Q9HC07,Q96ES6,Q70HW3
Functions
GO Molecular function
msigdb_gomf
99,71,40,73,178,79,144,53,152,118,90,156,157,63
53,1132,40,461,1666,79,1032,1033,73,1169,1170,694,2328,1743,1793,2257,2919,789,762,764,933,1174,993,2034,913,2556,647,791,1345,1590,2921,1596,1380,741,1412,152,850,800,696,2155,1648,1883,1848,63,178,1050,2424,2209,1886,144,157,90,349,637,1157,156,1582,118,370,71,2176,1585,99,1630,185
2.725483103215559,0.11162542503352747,2.9914106766594255,0.7261411670729521,-0.18226795279044486,2.4020229552889067,0.17770858414888777,0.17770858414888777,2.5328492892945635,0.0894578986082535,0.0894578986082535,0.4571356471709892,-0.5870410669585505,-0.22862872657474756,-0.2519294648126461,-0.5381064762809528,-1.3708103994508807,0.3723187418842105,0.39361707513132105,0.39361707513132105,0.24317501987691698,0.0894578986082535,0.19959848010973788,-0.3934676753169731,0.2648627970741298,-0.7613038169053663,0.4991726460209864,0.3723187418842105,7.238315672777529e-05,-0.13622316069244658,-1.3708103994508807,-0.13622316069244658,-0.022456018591835984,0.41485233449395625,-0.04505853001654639,1.6978944756633867,0.32953079791525924,0.3723187418842105,0.4571356471709892,-0.4653879408758077,-0.15920642504678456,-0.2987754614191971,-0.2753114513174612,2.62969443108639,1.553202877356439,0.17770858414888777,-0.6363489276465712,-0.4895375675230639,-0.2987754614191971,1.733666307759838,1.6619641606074178,2.269179628829763,0.9660662342487973,0.5200999892947062,0.11162542503352747,1.679949247910155,-0.11331744141047409,1.8927280853424016,0.9266068390226809,2.5652503504888915,-0.4653879408758077,-0.11331744141047409,2.1172115046276017,-0.13622316069244658,1.5166189935414305
3,040
Translocation
14
50
2.943892
0.003241
Q12769,Q9BTX1,O60830,Q99595,P62072,O60220,Q8N1F7,Q9NS69,Q8NFH4,Q15629,O75381,Q9BW27,O14925,Q9Y584
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
128,258,5,7,91,228,399,14,235,147,181,407,282,62
2437,282,1496,471,228,5,181,692,2669,2438,792,413,2935,2440,939,718,1509,850,2340,91,1315,128,147,803,1421,1148,399,2450,235,1391,1851,750,1852,1151,1055,1192,1058,724,7,258,2538,407,1200,14,1661,730,2854,62,758,2406
-0.6611452764022983,1.1411462025905137,-0.09048855958396525,0.7057948318332095,1.3123375484934685,5.283619928591475,1.5349318668753111,0.4571356471709892,-0.8630705208373466,-0.6611452764022983,0.3723187418842105,0.8069734811215312,-1.4268406552009354,-0.6611452764022983,0.24317501987691698,0.43602502551870426,-0.09048855958396525,0.32953079791525924,-0.5870410669585505,2.235643591481525,0.022527332531551376,1.8576465884962547,1.715800083261279,0.3723187418842105,-0.04505853001654639,0.11162542503352747,0.8470634843734169,-0.6611452764022983,1.2935010918758008,-0.022456018591835984,-0.2753114513174612,0.41485233449395625,-0.2753114513174612,0.11162542503352747,0.17770858414888777,0.0894578986082535,0.17770858414888777,0.43602502551870426,4.44501076876835,1.2367175827335657,-0.7361161262584145,0.8270453312183077,0.0894578986082535,3.703045056762135,-0.15920642504678456,0.43602502551870426,-1.151830630256655,2.661739823625172,0.41485233449395625,-0.6116478542652064
3,040
Organic acid transport
19
44
2.894072
0.003803
O60831,Q9NP80,P31751,P41440,Q9UJS0,Q6P4A7,O95563,O43772,Q9Y619,Q9H2D1,P09455,Q02978,O43808,P53985,Q9UBX3,P23786,Q8TDW0,Q9H936,P08183
Processes and pathways
GO Biological process
msigdb_gobp
504,134,520,146,557,289,167,40,185,66,195,583,461,95,232,106,236,637,255
40,461,504,1096,1500,167,1548,2551,787,1826,2552,255,1793,195,912,763,2974,106,622,2114,520,1075,146,1039,2268,95,1380,943,583,853,1080,1883,2001,289,1572,2424,236,66,637,1157,134,232,557,185
2.9914106766594255,0.7261411670729521,0.6649333439702259,0.13372264733385414,-0.09048855958396525,1.5896203443681522,-0.11331744141047409,-0.7613038169053663,0.3723187418842105,-0.2753114513174612,-0.7613038169053663,1.2367175827335657,-0.2519294648126461,1.4614265634176216,0.2648627970741298,0.39361707513132105,-1.6273031895761814,2.014354642413987,0.5200999892947062,-0.44132700120879625,0.6444173395953164,0.1557501687575436,1.715800083261279,0.17770858414888777,-0.5381064762809528,2.185089936053244,-0.022456018591835984,0.24317501987691698,0.5617747326313666,0.32953079791525924,0.1557501687575436,-0.2987754614191971,-0.36966757047407667,1.1025840074529036,-0.11331744141047409,-0.6363489276465712,1.2935010918758008,2.5975316656659477,0.5200999892947062,0.11162542503352747,1.804742035797999,1.3123375484934685,0.6032126407743291,1.5166189935414305
3,040
Glycosylation
15
45
2.889057
0.003864
Q9BT22,Q86SQ9,Q9Y5P6,O60502,Q86YN1,Q9BXS4,O15118,Q9H0U3,Q6ZXV5,P46977,Q9BV10,Q9HC07,Q10472,O43505,O00469
Processes and pathways
GO Biological process
msigdb_gobp
293,428,372,387,31,275,176,349,405,279,59,156,345,249,287
287,176,1368,249,710,1664,387,1497,1634,2520,2796,2700,1452,1406,1340,643,1219,279,1758,1317,2618,566,1513,345,1566,824,405,722,428,31,879,613,293,59,1154,275,349,2431,440,2175,156,2135,2434,1485,372
1.1025840074529036,1.553202877356439,-0.022456018591835984,1.2556914107011634,0.43602502551870426,-0.18226795279044486,0.867028329570998,-0.09048855958396525,-0.15920642504678456,-0.7361161262584145,-1.0452522464160021,-0.9145793033142863,-0.06773581807620718,-0.04505853001654639,7.238315672777529e-05,0.4991726460209864,0.06721945624007275,1.160355161006498,-0.22862872657474756,0.022527332531551376,-0.8119817547252068,0.582523062344913,-0.09048855958396525,0.9660662342487973,-0.11331744141047409,0.3509568225038281,0.8270453312183077,0.43602502551870426,0.7868475404440897,3.174513917781018,0.30804014209060904,0.5409671955712879,1.1025840074529036,2.67771886764343,0.11162542503352747,1.179516459667705,0.9660662342487973,-0.6363489276465712,0.7666671108145032,-0.4653879408758077,1.679949247910155,-0.44132700120879625,-0.6363489276465712,-0.06773581807620718,0.9266068390226809
3,040
Protein localization
31
71
2.83266
0.004616
Q13505,O60830,Q99595,Q8TB36,P40855,Q15067,Q9NR77,Q9NS69,Q13190,O14925,Q9UJS0,O43681,O14734,O75381,Q9Y584,O75431,Q8N4H5,Q15388,P21796,O43808,Q10713,P62072,O43615,O60220,Q9BY49,P51648,Q9Y512,Q5JRX3,Q96B49,O15254,P09601
Processes and pathways
Reactome Pathways
msigdb_reactome
3,5,7,391,388,521,11,14,142,282,557,545,299,181,62,558,199,463,211,461,215,91,471,228,498,244,248,362,117,120,121
1366,299,282,120,471,545,1165,461,228,5,181,2364,558,1299,2521,1096,962,1031,786,1373,694,2257,2144,121,2763,789,580,1036,211,1671,2556,622,2845,388,1592,670,2975,244,2195,1509,91,215,3029,142,3,521,463,803,362,199,1278,391,1234,117,7,2573,498,704,11,14,811,2245,1696,557,886,2137,248,62,758,2406,1899
-0.022456018591835984,1.063827239756187,1.1411462025905137,1.8752060118084188,0.7057948318332095,0.6032126407743291,0.0894578986082535,0.7261411670729521,1.3123375484934685,5.283619928591475,1.5349318668753111,-0.6116478542652064,0.582523062344913,0.022527332531551376,-0.7361161262584145,0.13372264733385414,0.22142043515709942,0.17770858414888777,0.3723187418842105,-0.022456018591835984,0.4571356471709892,-0.5381064762809528,-0.4653879408758077,1.8752060118084188,-0.9926509483185962,0.3723187418842105,0.5617747326313666,0.17770858414888777,1.3872343728517897,-0.18226795279044486,-0.7613038169053663,0.5200999892947062,-1.151830630256655,0.867028329570998,-0.13622316069244658,0.4781846919533493,-1.6273031895761814,1.2746191459726386,-0.4895375675230639,-0.09048855958396525,2.235643591481525,1.3685769357877944,-2.4411929362429676,1.7514933839084825,5.7379702431047095,0.6444173395953164,0.7261411670729521,0.3723187418842105,0.9266068390226809,1.4429435920810105,0.04490947737153897,0.867028329570998,0.06721945624007275,1.8927280853424016,4.44501076876835,-0.7613038169053663,0.6853923652184316,0.4571356471709892,3.9148541626840703,3.703045056762135,0.3723187418842105,-0.5137767760722269,-0.18226795279044486,0.6032126407743291,0.30804014209060904,-0.44132700120879625,1.2746191459726386,2.661739823625172,0.41485233449395625,-0.6116478542652064,-0.2987754614191971
3,040
Pigmentary retinopathy
12
45
2.784491
0.005361
Q9BSH4,O75643,Q16836,P00846,Q15555,Q96CU9,Q7KZN9,P03886,Q9UG56,P40939,O75306,Q9BUK6
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
325,162,39,73,204,108,178,47,247,212,57,126
1028,1294,1166,1450,57,785,162,1097,2550,1033,73,47,2553,1709,1551,2911,2147,2647,1456,212,3004,1987,1714,2975,650,2585,521,204,1354,39,178,1047,1049,1427,108,1616,325,126,1196,2175,1438,906,247,372,2357
0.17770858414888777,0.022527332531551376,0.0894578986082535,-0.06773581807620718,2.67771886764343,0.3723187418842105,1.6077673117097622,0.13372264733385414,-0.7613038169053663,0.17770858414888777,2.5328492892945635,2.929545586146746,-0.7613038169053663,-0.20540847316623317,-0.11331744141047409,-1.3429937902950162,-0.4653879408758077,-0.8374742177649565,-0.06773581807620718,1.3872343728517897,-1.8958578566794209,-0.36966757047407667,-0.20540847316623317,-1.6273031895761814,0.4991726460209864,-0.7865919937038053,0.6444173395953164,1.4244174208729259,7.238315672777529e-05,3.006810954254387,1.553202877356439,0.17770858414888777,0.17770858414888777,-0.04505853001654639,1.9797856725780703,-0.13622316069244658,1.005321354697109,1.8752060118084188,0.0894578986082535,-0.4653879408758077,-0.04505853001654639,0.28648432191911377,1.2746191459726386,0.9266068390226809,-0.5870410669585505
3,040
Intrinsic component of mitochondrial inner membrane
12
34
2.773553
0.005545
Q13505,O60830,Q15070,Q99595,Q8N8Q8,O95563,Q9H4I9,Q9Y512,Q9UG56,Q9Y2R0,Q9BUR5,O14925
Localization
GO Cellular component
msigdb_gocc
3,5,196,7,264,167,200,248,247,86,184,282
282,1209,5,558,559,167,1504,2845,1715,696,3,196,1720,1044,587,466,289,2448,264,2209,7,184,572,200,1157,1021,1582,810,811,247,86,1365,248,837
1.1411462025905137,0.06721945624007275,5.283619928591475,0.582523062344913,0.582523062344913,1.5896203443681522,-0.09048855958396525,-1.151830630256655,-0.20540847316623317,0.4571356471709892,5.7379702431047095,1.4614265634176216,-0.20540847316623317,0.17770858414888777,0.5617747326313666,0.7261411670729521,1.1025840074529036,-0.6611452764022983,1.1986304188795078,-0.4895375675230639,4.44501076876835,1.5166189935414305,0.582523062344913,1.4429435920810105,0.11162542503352747,0.19959848010973788,-0.11331744141047409,0.3723187418842105,0.3723187418842105,1.2746191459726386,2.352447611616457,7.238315672777529e-05,1.2746191459726386,0.3509568225038281
3,040
Glycoprotein biosynthetic process
17
53
2.745279
0.006046
Q9BT22,Q9Y5P6,O60502,O14734,Q86YN1,Q9BXS4,Q7LGA3,O15118,Q9H0U3,Q6ZXV5,P46977,Q8NCH0,Q9BV10,Q9HC07,Q10472,O43505,O00469
Processes and pathways
GO Biological process
msigdb_gobp
293,372,387,299,31,275,187,176,349,405,279,280,59,156,345,249,287
287,299,176,1368,249,710,1664,387,1497,1870,1634,2520,2700,1406,1340,643,1752,1985,1219,279,1758,1317,2618,566,1513,345,1566,824,405,187,722,428,31,280,879,1016,2736,613,977,293,59,1154,275,349,2431,1127,2175,156,1159,2717,2434,1485,372
1.1025840074529036,1.063827239756187,1.553202877356439,-0.022456018591835984,1.2556914107011634,0.43602502551870426,-0.18226795279044486,0.867028329570998,-0.09048855958396525,-0.2987754614191971,-0.15920642504678456,-0.7361161262584145,-0.9145793033142863,-0.04505853001654639,7.238315672777529e-05,0.4991726460209864,-0.22862872657474756,-0.36966757047407667,0.06721945624007275,1.160355161006498,-0.22862872657474756,0.022527332531551376,-0.8119817547252068,0.582523062344913,-0.09048855958396525,0.9660662342487973,-0.11331744141047409,0.3509568225038281,0.8270453312183077,1.4982639954012558,0.43602502551870426,0.7868475404440897,3.174513917781018,1.160355161006498,0.30804014209060904,0.19959848010973788,-0.9404941645246845,0.5409671955712879,0.22142043515709942,1.1025840074529036,2.67771886764343,0.11162542503352747,1.179516459667705,0.9660662342487973,-0.6363489276465712,0.13372264733385414,-0.4653879408758077,1.679949247910155,0.11162542503352747,-0.9145793033142863,-0.6363489276465712,-0.06773581807620718,0.9266068390226809
3,040
Mitochondrial membrane organization
12
50
2.699493
0.006945
P45880,Q13505,Q15070,Q8N8Q8,O60220,Q9NS69,Q9Y512,O14737,Q9BUR5,P62072,Q96E52,Q9Y584
Processes and pathways
GO Biological process
msigdb_gobp
192,3,196,264,228,14,248,180,184,91,124,62
1631,180,228,989,558,1031,1211,1032,1168,1170,2066,1706,319,789,1504,2890,2993,2781,2845,2117,192,1410,2975,1040,91,3,196,1044,803,587,466,2448,1771,1611,1084,264,124,184,572,14,810,811,906,1486,886,1365,248,62,758,2406
-0.15920642504678456,1.5349318668753111,1.3123375484934685,0.19959848010973788,0.582523062344913,0.17770858414888777,0.06721945624007275,0.17770858414888777,0.0894578986082535,0.0894578986082535,-0.4173538681027949,-0.20540847316623317,1.005321354697109,0.3723187418842105,-0.09048855958396525,-1.2603180196379737,-1.7749118188298865,-1.0188953886833905,-1.151830630256655,-0.44132700120879625,1.4798666078148721,-0.04505853001654639,-1.6273031895761814,0.17770858414888777,2.235643591481525,5.7379702431047095,1.4614265634176216,0.17770858414888777,0.3723187418842105,0.5617747326313666,0.7261411670729521,-0.6611452764022983,-0.22862872657474756,-0.13622316069244658,0.1557501687575436,1.1986304188795078,1.8752060118084188,1.5166189935414305,0.582523062344913,3.703045056762135,0.3723187418842105,0.3723187418842105,0.28648432191911377,-0.06773581807620718,0.30804014209060904,7.238315672777529e-05,1.2746191459726386,2.661739823625172,0.41485233449395625,-0.6116478542652064
3,040
Regulation of hmox1 expression and activity
10
45
2.695205
0.007035
P49721,P28072,P49720,P20618,Q8TCT9,P28070,P60900,P28074,P09601,Q05655
Processes and pathways
Reactome Pathways
msigdb_reactome
32,260,133,138,347,177,50,242,121,314
839,1663,1293,2721,1094,991,121,2146,1407,138,2068,844,621,1072,1106,177,260,242,2468,1834,794,133,32,1000,1598,50,916,1798,1799,2081,771,1349,314,1267,2156,2420,1921,2477,1270,347,550,367,2010,756,1489
0.32953079791525924,-0.18226795279044486,0.022527332531551376,-0.9404941645246845,0.13372264733385414,0.19959848010973788,1.8752060118084188,-0.4653879408758077,-0.04505853001654639,1.7692815441810628,-0.4173538681027949,0.32953079791525924,0.5200999892947062,0.1557501687575436,0.13372264733385414,1.553202877356439,1.2176973554481503,1.2746191459726386,-0.6860379068899511,-0.2753114513174612,0.3723187418842105,1.804742035797999,3.1290816434117823,0.19959848010973788,-0.13622316069244658,2.8202460802749503,0.2648627970741298,-0.2519294648126461,-0.2519294648126461,-0.4173538681027949,0.39361707513132105,7.238315672777529e-05,1.0248732054561662,0.04490947737153897,-0.4653879408758077,-0.6363489276465712,-0.32232228259890044,-0.6860379068899511,0.04490947737153897,0.9660662342487973,0.6032126407743291,0.9266068390226809,-0.36966757047407667,0.41485233449395625,-0.06773581807620718
3,040
Optic disc pallor
17
51
2.690683
0.007131
P51798,Q86Y39,O75643,Q9H061,P00846,Q86WC4,Q96CU9,Q9GZY8,P03886,Q9UG56,Q9NPL8,O43676,O96000,Q10713,O75306,O95831,Q9BUK6
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
477,164,162,41,73,337,108,368,47,247,441,269,311,215,57,381,126
489,2360,688,1787,269,1166,989,1450,57,1299,785,162,1211,381,311,73,47,1453,2067,1980,1709,2911,1987,477,2858,215,969,337,164,2713,1049,2697,2166,1427,2095,108,613,1616,2632,126,368,41,860,615,441,1438,1483,247,1732,1365,2844
0.6853923652184316,-0.6116478542652064,0.4571356471709892,-0.2519294648126461,1.179516459667705,0.0894578986082535,0.19959848010973788,-0.06773581807620718,2.67771886764343,0.022527332531551376,0.3723187418842105,1.6077673117097622,0.06721945624007275,0.8869402512163685,1.0248732054561662,2.5328492892945635,2.929545586146746,-0.06773581807620718,-0.4173538681027949,-0.36966757047407667,-0.20540847316623317,-1.3429937902950162,-0.36966757047407667,0.7057948318332095,-1.1787698895200653,1.3685769357877944,0.22142043515709942,0.9857191490793755,1.6077673117097622,-0.9145793033142863,0.17770858414888777,-0.888771822686556,-0.4653879408758077,-0.04505853001654639,-0.4173538681027949,1.9797856725780703,0.5409671955712879,-0.13622316069244658,-0.8119817547252068,1.8752060118084188,0.9266068390226809,2.9914106766594255,0.32953079791525924,0.5409671955712879,0.7666671108145032,-0.04505853001654639,-0.06773581807620718,1.2746191459726386,-0.20540847316623317,7.238315672777529e-05,-1.1250106483577362
3,040
Oxidative phosphorylation
14
56
2.687398
0.007201
Q86Y39,Q9Y487,Q9UDW1,P00846,Q7KZN9,P03886,Q93050,O75964,P14406,O43676,P61421,O75438,O75306,O14949
Processes and pathways
KEGG Pathways
msigdb_kegg
164,99,71,73,178,47,144,79,19,269,152,240,57,190
1028,1132,190,269,1450,57,240,785,1666,79,473,2550,311,1033,73,47,694,2257,2919,762,19,1640,1709,1174,993,2034,1551,360,913,2556,2911,2647,647,791,1345,1590,2921,1987,847,741,1412,152,2384,1353,2657,1354,178,164,144,1892,71,2176,99,1630,2844,837
0.17770858414888777,0.11162542503352747,1.4798666078148721,1.179516459667705,-0.06773581807620718,2.67771886764343,1.2746191459726386,0.3723187418842105,-0.18226795279044486,2.4020229552889067,0.7057948318332095,-0.7613038169053663,1.0248732054561662,0.17770858414888777,2.5328492892945635,2.929545586146746,0.4571356471709892,-0.5381064762809528,-1.3708103994508807,0.39361707513132105,3.5010292750882246,-0.15920642504678456,-0.20540847316623317,0.0894578986082535,0.19959848010973788,-0.3934676753169731,-0.11331744141047409,0.9266068390226809,0.2648627970741298,-0.7613038169053663,-1.3429937902950162,-0.8374742177649565,0.4991726460209864,0.3723187418842105,7.238315672777529e-05,-0.13622316069244658,-1.3708103994508807,-0.36966757047407667,0.32953079791525924,0.41485233449395625,-0.04505853001654639,1.6978944756633867,-0.6116478542652064,7.238315672777529e-05,-0.8374742177649565,7.238315672777529e-05,1.553202877356439,1.6077673117097622,1.733666307759838,-0.2987754614191971,2.5652503504888915,-0.4653879408758077,2.1172115046276017,-0.13622316069244658,-1.1250106483577362,0.3509568225038281
3,040
Mitochondrial protein import
12
37
2.638088
0.008337
Q13505,O60830,Q99595,Q8N4H5,O60220,Q9NS69,Q9Y512,P21796,Q96B49,Q10713,P62072,Q9Y584
Processes and pathways
Reactome Pathways
msigdb_reactome
3,5,7,199,228,14,248,211,117,215,91,62
282,471,228,5,2364,558,1299,1096,1031,786,694,2257,2763,789,580,211,2556,2845,91,215,3,463,803,362,199,117,7,2573,704,14,811,557,886,248,62,758,2406
1.1411462025905137,0.7057948318332095,1.3123375484934685,5.283619928591475,-0.6116478542652064,0.582523062344913,0.022527332531551376,0.13372264733385414,0.17770858414888777,0.3723187418842105,0.4571356471709892,-0.5381064762809528,-0.9926509483185962,0.3723187418842105,0.5617747326313666,1.3872343728517897,-0.7613038169053663,-1.151830630256655,2.235643591481525,1.3685769357877944,5.7379702431047095,0.7261411670729521,0.3723187418842105,0.9266068390226809,1.4429435920810105,1.8927280853424016,4.44501076876835,-0.7613038169053663,0.4571356471709892,3.703045056762135,0.3723187418842105,0.6032126407743291,0.30804014209060904,1.2746191459726386,2.661739823625172,0.41485233449395625,-0.6116478542652064
3,040
Intrinsic component of endoplasmic reticulum membrane
21
54
2.626057
0.008638
P57088,Q16799,Q15629,Q96A33,Q969N2,O43826,Q9Y282,Q86YN1,Q03518,Q9BUN8,Q15006,Q96S52,Q9Y4P3,Q8TCT8,O75844,Q9P035,Q8TCT9,Q86XL3,Q9NQC3,O95470,Q92643
Localization
GO Cellular component
msigdb_gocc
384,390,147,541,406,151,24,31,425,168,426,438,444,194,69,339,347,94,226,380,508
1130,708,1701,1821,151,69,1097,380,1098,1453,888,1215,1105,2746,1223,384,850,425,3007,1995,426,853,3028,147,390,655,1474,2160,94,31,1050,723,629,194,347,508,406,541,438,1058,1724,168,2096,1245,2487,226,555,339,1661,908,1585,24,444,707
0.11162542503352747,0.43602502551870426,-0.20540847316623317,-0.2753114513174612,1.6978944756633867,2.5652503504888915,0.13372264733385414,0.8869402512163685,0.13372264733385414,-0.06773581807620718,0.28648432191911377,0.06721945624007275,0.13372264733385414,-0.9665176304872712,0.06721945624007275,0.8869402512163685,0.32953079791525924,0.7868475404440897,-1.9265112413148566,-0.36966757047407667,0.7868475404440897,0.32953079791525924,-2.4076910053251255,1.715800083261279,0.867028329570998,0.4991726460209864,-0.06773581807620718,-0.4653879408758077,2.2019746742666584,3.174513917781018,0.17770858414888777,0.43602502551870426,0.5200999892947062,1.4798666078148721,0.9660662342487973,0.6649333439702259,0.8270453312183077,0.6238439182752883,0.7666671108145032,0.17770858414888777,-0.20540847316623317,1.5896203443681522,-0.4173538681027949,0.06721945624007275,-0.6860379068899511,1.3311288127114365,0.6032126407743291,0.9857191490793755,-0.15920642504678456,0.28648432191911377,-0.11331744141047409,3.3688375992261888,0.7666671108145032,0.4571356471709892
3,040
Mitochondrial transport
29
83
2.577387
0.009955
Q14849,O60830,P55786,Q99595,Q8N8Q8,Q8TB36,Q9NS69,O14925,Q96EK5,O43772,O14737,Q99797,O95429,Q9Y584,P45880,Q15070,Q8N4H5,P00846,O75964,Q15388,Q10713,P62072,Q9UBX3,O60220,P23786,Q9GZY8,Q9Y512,Q5JRX3,O95831
Processes and pathways
GO Biological process
msigdb_gobp
131,5,6,7,264,391,14,282,430,40,180,54,432,62,192,196,199,73,79,463,215,91,232,228,106,368,248,362,381
2105,180,282,503,471,40,228,5,1298,558,1299,1666,79,1031,1211,432,641,381,786,73,1168,1170,694,2066,1706,2763,789,1407,106,913,2556,2890,2993,2781,791,2117,192,2921,2305,1410,1039,1223,1040,6,741,1412,91,1182,215,131,196,463,2822,803,587,362,972,2389,1611,1084,199,264,391,430,829,7,54,368,704,2217,14,906,2542,232,1486,557,1815,886,3002,248,62,758,2406
-0.44132700120879625,1.5349318668753111,1.1411462025905137,0.6649333439702259,0.7057948318332095,2.9914106766594255,1.3123375484934685,5.283619928591475,0.022527332531551376,0.582523062344913,0.022527332531551376,-0.18226795279044486,2.4020229552889067,0.17770858414888777,0.06721945624007275,0.7666671108145032,0.4991726460209864,0.8869402512163685,0.3723187418842105,2.5328492892945635,0.0894578986082535,0.0894578986082535,0.4571356471709892,-0.4173538681027949,-0.20540847316623317,-0.9926509483185962,0.3723187418842105,-0.04505853001654639,2.014354642413987,0.2648627970741298,-0.7613038169053663,-1.2603180196379737,-1.7749118188298865,-1.0188953886833905,0.3723187418842105,-0.44132700120879625,1.4798666078148721,-1.3708103994508807,-0.5625275930863287,-0.04505853001654639,0.17770858414888777,0.06721945624007275,0.17770858414888777,5.13606374568797,0.41485233449395625,-0.04505853001654639,2.235643591481525,0.0894578986082535,1.3685769357877944,1.8400495980357443,1.4614265634176216,0.7261411670729521,-1.071722841162979,0.3723187418842105,0.5617747326313666,0.9266068390226809,0.22142043515709942,-0.6116478542652064,-0.13622316069244658,0.1557501687575436,1.4429435920810105,1.1986304188795078,0.867028329570998,0.7868475404440897,0.3509568225038281,4.44501076876835,2.725483103215559,0.9266068390226809,0.4571356471709892,-0.4895375675230639,3.703045056762135,0.28648432191911377,-0.7361161262584145,1.3123375484934685,-0.06773581807620718,0.6032126407743291,-0.2519294648126461,0.30804014209060904,-1.8653737098684169,1.2746191459726386,2.661739823625172,0.41485233449395625,-0.6116478542652064
3,040
Signaling by the b cell receptor bcr
9
45
2.551882
0.010714
P49721,P62942,P28072,P49720,Q99436,P20618,P28070,P60900,P28074
Processes and pathways
Reactome Pathways
msigdb_reactome
32,130,260,133,367,138,177,50,242
1734,839,1663,1293,2721,1068,373,1094,1297,991,2146,138,2068,844,621,1072,1106,177,260,242,2468,1834,794,133,32,1000,1598,50,916,1798,1799,2081,130,720,771,1267,917,2156,1921,1270,550,367,2010,756,1489
-0.22862872657474756,0.32953079791525924,-0.18226795279044486,0.022527332531551376,-0.9404941645246845,0.1557501687575436,0.9067996292104508,0.13372264733385414,0.022527332531551376,0.19959848010973788,-0.4653879408758077,1.7692815441810628,-0.4173538681027949,0.32953079791525924,0.5200999892947062,0.1557501687575436,0.13372264733385414,1.553202877356439,1.2176973554481503,1.2746191459726386,-0.6860379068899511,-0.2753114513174612,0.3723187418842105,1.804742035797999,3.1290816434117823,0.19959848010973788,-0.13622316069244658,2.8202460802749503,0.2648627970741298,-0.2519294648126461,-0.2519294648126461,-0.4173538681027949,1.8400495980357443,0.43602502551870426,0.39361707513132105,0.04490947737153897,0.2648627970741298,-0.4653879408758077,-0.32232228259890044,0.04490947737153897,0.6032126407743291,0.9266068390226809,-0.36966757047407667,0.41485233449395625,-0.06773581807620718
3,040
Phospholipid biosynthetic process
25
60
2.54321
0.010984
Q8NF37,Q5H8A4,Q9NPH0,Q969N2,Q9NUQ2,Q86YN1,Q96PE3,O15269,Q86SQ9,Q96S52,P35790,O15270,Q6P1A2,Q96N66,Q8TBX8,Q08AM6,O14735,Q9BTU6,Q10713,P42356,Q86UL3,Q9HBU6,Q9UG56,Q7L5N7,Q92643
Processes and pathways
GO Biological process
msigdb_gobp
659,655,18,406,153,31,35,666,428,438,435,689,61,197,594,451,446,468,215,716,483,96,247,628,508
1131,446,666,689,1701,1634,962,1548,1212,1739,1825,3026,1667,1214,1828,435,716,2265,943,1801,2505,451,215,1386,1567,2589,655,1609,61,628,428,483,31,1052,659,594,1015,1810,1325,508,406,197,35,438,2011,1857,468,1436,2096,96,755,18,1399,1285,153,1628,2245,907,247,1485
0.11162542503352747,0.7464317890494901,0.4781846919533493,0.4571356471709892,-0.20540847316623317,-0.15920642504678456,0.22142043515709942,-0.11331744141047409,0.06721945624007275,-0.22862872657474756,-0.2753114513174612,-2.374364065437545,-0.18226795279044486,0.06721945624007275,-0.2753114513174612,0.7666671108145032,0.43602502551870426,-0.5381064762809528,0.24317501987691698,-0.2519294648126461,-0.7110278429358069,0.7464317890494901,1.3685769357877944,-0.022456018591835984,-0.11331744141047409,-0.7865919937038053,0.4991726460209864,-0.13622316069244658,2.661739823625172,0.5200999892947062,0.7868475404440897,0.7057948318332095,3.174513917781018,0.17770858414888777,0.4991726460209864,0.5617747326313666,0.19959848010973788,-0.2519294648126461,0.022527332531551376,0.6649333439702259,0.8270453312183077,1.4614265634176216,3.0834224304076256,0.7666671108145032,-0.36966757047407667,-0.2753114513174612,0.7261411670729521,-0.04505853001654639,-0.4173538681027949,2.185089936053244,0.41485233449395625,3.573673225714372,-0.022456018591835984,0.04490947737153897,1.6978944756633867,-0.13622316069244658,-0.5137767760722269,0.28648432191911377,1.2746191459726386,-0.06773581807620718
3,040
Secondary alcohol metabolic process
14
43
2.530583
0.011387
Q06520,Q14849,Q15800,P54646,Q14739,Q16850,Q15392,P16435,Q9H2C2,O15118,Q8WTV0,Q9BQE5,Q6P1A2,P48735
Processes and pathways
GO Biological process
msigdb_gobp
98,131,101,478,335,76,143,423,369,176,22,25,61,193
176,1166,2325,962,1636,911,1452,1373,1035,1667,423,581,1985,1218,2117,1308,193,2581,1714,1755,478,2339,2830,1801,98,1567,495,335,131,1650,3028,2589,143,2385,101,76,61,22,2573,25,369,908,2402
1.553202877356439,0.0894578986082535,-0.5870410669585505,0.22142043515709942,-0.15920642504678456,0.2648627970741298,-0.06773581807620718,-0.022456018591835984,0.17770858414888777,-0.18226795279044486,0.7868475404440897,0.5617747326313666,-0.36966757047407667,0.06721945624007275,-0.44132700120879625,0.022527332531551376,1.4798666078148721,-0.7865919937038053,-0.20540847316623317,-0.22862872657474756,0.7057948318332095,-0.5870410669585505,-1.0983085180476655,-0.2519294648126461,2.134232406148761,-0.11331744141047409,0.6853923652184316,0.9857191490793755,1.8400495980357443,-0.15920642504678456,-2.4076910053251255,-0.7865919937038053,1.7514933839084825,-0.6116478542652064,2.100156093249775,2.484020507983507,2.661739823625172,3.4278200746104854,-0.7613038169053663,3.324354402709241,0.9266068390226809,0.28648432191911377,-0.6116478542652064
3,040
Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1
10
46
2.523741
0.011611
P49721,P28072,P49720,Q9UJX2,P20618,P28070,P60900,P28074,Q96DE5,Q9UJX3
Processes and pathways
Reactome Pathways
msigdb_reactome
32,260,133,233,138,177,50,242,281,328
839,1663,1293,2721,734,1094,991,2146,138,2068,844,621,1072,1106,177,260,242,1217,2468,1834,794,133,32,1000,2377,1598,50,916,1798,1799,2081,1267,2156,2420,1270,625,550,281,367,2010,1967,233,328,1290,756,1489
0.32953079791525924,-0.18226795279044486,0.022527332531551376,-0.9404941645246845,0.41485233449395625,0.13372264733385414,0.19959848010973788,-0.4653879408758077,1.7692815441810628,-0.4173538681027949,0.32953079791525924,0.5200999892947062,0.1557501687575436,0.13372264733385414,1.553202877356439,1.2176973554481503,1.2746191459726386,0.06721945624007275,-0.6860379068899511,-0.2753114513174612,0.3723187418842105,1.804742035797999,3.1290816434117823,0.19959848010973788,-0.6116478542652064,-0.13622316069244658,2.8202460802749503,0.2648627970741298,-0.2519294648126461,-0.2519294648126461,-0.4173538681027949,0.04490947737153897,-0.4653879408758077,-0.6363489276465712,0.04490947737153897,0.5200999892947062,0.6032126407743291,1.160355161006498,0.9266068390226809,-0.36966757047407667,-0.3459527147544944,1.3123375484934685,1.005321354697109,0.04490947737153897,0.41485233449395625,-0.06773581807620718
3,040
Cellular modified amino acid metabolic process
16
54
2.518895
0.011772
Q9H7Z7,Q9H2D1,Q06520,Q9UJ14,Q8TB36,Q9UHG3,P23786,Q9NVH6,P49419,Q8NCC3,P41440,Q8N2K0,O60725,P78417,Q6P1A2,O00469
Processes and pathways
GO Biological process
msigdb_gobp
386,66,98,393,391,42,106,111,16,17,146,304,52,122,61,287
2519,287,1633,1497,52,962,1500,505,1740,2551,2365,1872,818,1035,2524,2689,2959,2188,423,1376,1829,106,2069,2414,475,740,146,1136,3004,2265,1713,16,1039,122,1350,98,2423,61,2087,1477,304,17,391,2314,2894,2281,2317,66,386,678,111,42,393,2137
-0.7361161262584145,1.1025840074529036,-0.15920642504678456,-0.09048855958396525,2.741347351975947,0.22142043515709942,-0.09048855958396525,0.6649333439702259,-0.22862872657474756,-0.7613038169053663,-0.6116478542652064,-0.2987754614191971,0.3509568225038281,0.17770858414888777,-0.7361161262584145,-0.888771822686556,-1.511904869971841,-0.4895375675230639,0.7868475404440897,-0.022456018591835984,-0.2753114513174612,2.014354642413987,-0.4173538681027949,-0.6363489276465712,0.7057948318332095,0.41485233449395625,1.715800083261279,0.11162542503352747,-1.8958578566794209,-0.5381064762809528,-0.20540847316623317,3.631389293268725,0.17770858414888777,1.8752060118084188,7.238315672777529e-05,2.134232406148761,-0.6363489276465712,2.661739823625172,-0.4173538681027949,-0.06773581807620718,1.063827239756187,3.6025751739028236,0.867028329570998,-0.5625275930863287,-1.2603180196379737,-0.5381064762809528,-0.5625275930863287,2.5975316656659477,0.8869402512163685,0.4781846919533493,1.962447158057928,2.9914106766594255,0.867028329570998,-0.44132700120879625
3,040
Inorganic molecular entity transmembrane transporter activity
19
71
2.512801
0.011978
Q93050,P61421,O43826,Q9HC07,Q96ES6,Q7KZN9,O00400,Q99797,P45880,Q9UDW1,P00846,O75964,P21796,Q9H0U3,Q9Y487,Q9UBX3,Q9P246,Q8TDW0,Q9HD20
Functions
GO Molecular function
msigdb_gomf
144,152,151,156,157,178,53,54,192,71,73,79,211,349,99,232,370,236,118
2519,53,1132,545,151,1666,79,1032,1033,73,1169,1170,694,2328,1743,1793,2257,2111,2919,789,762,764,933,1174,993,2034,211,913,2556,647,791,1345,1590,192,2921,1596,477,1380,741,1412,152,850,800,696,2155,583,1648,548,178,1050,2424,2209,236,144,157,1616,54,1241,349,637,156,118,370,232,71,2176,1585,394,99,1630,1205
-0.7361161262584145,2.725483103215559,0.11162542503352747,0.6032126407743291,1.6978944756633867,-0.18226795279044486,2.4020229552889067,0.17770858414888777,0.17770858414888777,2.5328492892945635,0.0894578986082535,0.0894578986082535,0.4571356471709892,-0.5870410669585505,-0.22862872657474756,-0.2519294648126461,-0.5381064762809528,-0.44132700120879625,-1.3708103994508807,0.3723187418842105,0.39361707513132105,0.39361707513132105,0.24317501987691698,0.0894578986082535,0.19959848010973788,-0.3934676753169731,1.3872343728517897,0.2648627970741298,-0.7613038169053663,0.4991726460209864,0.3723187418842105,7.238315672777529e-05,-0.13622316069244658,1.4798666078148721,-1.3708103994508807,-0.13622316069244658,0.7057948318332095,-0.022456018591835984,0.41485233449395625,-0.04505853001654639,1.6978944756633867,0.32953079791525924,0.3723187418842105,0.4571356471709892,-0.4653879408758077,0.5617747326313666,-0.15920642504678456,0.6032126407743291,1.553202877356439,0.17770858414888777,-0.6363489276465712,-0.4895375675230639,1.2935010918758008,1.733666307759838,1.6619641606074178,-0.13622316069244658,2.725483103215559,0.06721945624007275,0.9660662342487973,0.5200999892947062,1.679949247910155,1.8927280853424016,0.9266068390226809,1.3123375484934685,2.5652503504888915,-0.4653879408758077,-0.11331744141047409,0.867028329570998,2.1172115046276017,-0.13622316069244658,0.0894578986082535
3,040
Proteasome core complex beta subunit complex
6
7
2.467674
0.013599
P49721,P28072,P49720,P20618,P28070,P28074
Localization
GO Cellular component
msigdb_gocc
32,260,133,138,177,242
138,177,260,242,133,32,367
1.7692815441810628,1.553202877356439,1.2176973554481503,1.2746191459726386,1.804742035797999,3.1290816434117823,0.9266068390226809
3,040
Proteasome B-type subunit [IPR023333]
6
7
2.467674
0.013599
P49721,P28072,P49720,P20618,P28070,P28074
Sequence
InterPro Family
interpro_family
32,260,133,138,177,242
138,177,260,242,133,32,367
1.7692815441810628,1.553202877356439,1.2176973554481503,1.2746191459726386,1.804742035797999,3.1290816434117823,0.9266068390226809
3,040
Abc family proteins mediated transport
11
49
2.460029
0.013893
P49721,P28072,P49720,Q9BUN8,Q99436,P20618,Q9UBV2,P28070,P60900,P28074,P08183
Processes and pathways
Reactome Pathways
msigdb_reactome
32,260,133,168,367,138,209,177,50,242,255
839,1663,1293,2721,1094,1499,2325,991,1636,1099,255,2146,2224,138,2068,844,621,1072,1106,177,260,242,622,2468,388,1834,794,133,32,1000,1598,2197,50,916,1798,1799,2081,1267,2156,1270,898,550,367,2010,168,2217,209,756,1489
0.32953079791525924,-0.18226795279044486,0.022527332531551376,-0.9404941645246845,0.13372264733385414,-0.09048855958396525,-0.5870410669585505,0.19959848010973788,-0.15920642504678456,0.13372264733385414,1.2367175827335657,-0.4653879408758077,-0.5137767760722269,1.7692815441810628,-0.4173538681027949,0.32953079791525924,0.5200999892947062,0.1557501687575436,0.13372264733385414,1.553202877356439,1.2176973554481503,1.2746191459726386,0.5200999892947062,-0.6860379068899511,0.867028329570998,-0.2753114513174612,0.3723187418842105,1.804742035797999,3.1290816434117823,0.19959848010973788,-0.13622316069244658,-0.4895375675230639,2.8202460802749503,0.2648627970741298,-0.2519294648126461,-0.2519294648126461,-0.4173538681027949,0.04490947737153897,-0.4653879408758077,0.04490947737153897,0.28648432191911377,0.6032126407743291,0.9266068390226809,-0.36966757047407667,1.5896203443681522,-0.4895375675230639,1.405847774017092,0.41485233449395625,-0.06773581807620718
3,040
Ion transmembrane transporter activity
28
96
2.457899
0.013975
Q93050,P41440,P61421,O43826,Q9HC07,Q96ES6,Q6P4A7,O95563,O43772,Q7KZN9,O00400,Q9Y619,Q70HW3,Q9H2D1,P45880,Q9UDW1,P00846,O75964,P21796,Q99808,Q9H0U3,P53985,Q9Y487,Q9UBX3,Q9P246,Q8TDW0,Q14728,Q9HD20
Functions
GO Molecular function
msigdb_gomf
144,146,152,151,156,157,289,167,40,178,53,185,63,66,192,71,73,79,211,90,349,95,99,232,370,236,245,118
2519,53,1132,545,40,461,151,1096,1666,79,1032,167,1033,73,1169,1170,694,2328,1743,1793,2257,2111,2919,912,789,580,762,764,933,1174,993,2034,211,913,2556,647,791,1345,1590,146,192,2921,1596,477,2268,95,1380,741,1412,152,850,800,696,2155,583,1648,245,2276,1883,548,972,2001,289,1848,63,178,1050,2424,2209,1886,629,236,144,157,1616,90,2537,1241,349,66,637,1157,156,1582,118,370,232,71,2176,557,1585,394,99,1630,185,1205
-0.7361161262584145,2.725483103215559,0.11162542503352747,0.6032126407743291,2.9914106766594255,0.7261411670729521,1.6978944756633867,0.13372264733385414,-0.18226795279044486,2.4020229552889067,0.17770858414888777,1.5896203443681522,0.17770858414888777,2.5328492892945635,0.0894578986082535,0.0894578986082535,0.4571356471709892,-0.5870410669585505,-0.22862872657474756,-0.2519294648126461,-0.5381064762809528,-0.44132700120879625,-1.3708103994508807,0.2648627970741298,0.3723187418842105,0.5617747326313666,0.39361707513132105,0.39361707513132105,0.24317501987691698,0.0894578986082535,0.19959848010973788,-0.3934676753169731,1.3872343728517897,0.2648627970741298,-0.7613038169053663,0.4991726460209864,0.3723187418842105,7.238315672777529e-05,-0.13622316069244658,1.715800083261279,1.4798666078148721,-1.3708103994508807,-0.13622316069244658,0.7057948318332095,-0.5381064762809528,2.185089936053244,-0.022456018591835984,0.41485233449395625,-0.04505853001654639,1.6978944756633867,0.32953079791525924,0.3723187418842105,0.4571356471709892,-0.4653879408758077,0.5617747326313666,-0.15920642504678456,1.2746191459726386,-0.5381064762809528,-0.2987754614191971,0.6032126407743291,0.22142043515709942,-0.36966757047407667,1.1025840074529036,-0.2753114513174612,2.62969443108639,1.553202877356439,0.17770858414888777,-0.6363489276465712,-0.4895375675230639,-0.2987754614191971,0.5200999892947062,1.2935010918758008,1.733666307759838,1.6619641606074178,-0.13622316069244658,2.269179628829763,-0.7361161262584145,0.06721945624007275,0.9660662342487973,2.5975316656659477,0.5200999892947062,0.11162542503352747,1.679949247910155,-0.11331744141047409,1.8927280853424016,0.9266068390226809,1.3123375484934685,2.5652503504888915,-0.4653879408758077,0.6032126407743291,-0.11331744141047409,0.867028329570998,2.1172115046276017,-0.13622316069244658,1.5166189935414305,0.0894578986082535
3,040
Proteasome beta-type subunit, conserved site [IPR016050]
6
8
2.430258
0.015088
P49721,P28072,P49720,P20618,P28070,P28074
Sequence
InterPro Conserved site
interpro_conserved_site
32,260,133,138,177,242
138,1072,177,260,242,133,32,367
1.7692815441810628,0.1557501687575436,1.553202877356439,1.2176973554481503,1.2746191459726386,1.804742035797999,3.1290816434117823,0.9266068390226809
3,040
Threonine type endopeptidase activity
6
8
2.430258
0.015088
P49721,P28072,P49720,P20618,P28070,P28074
Functions
GO Molecular function
msigdb_gomf
32,260,133,138,177,242
138,1072,177,260,242,133,32,367
1.7692815441810628,0.1557501687575436,1.553202877356439,1.2176973554481503,1.2746191459726386,1.804742035797999,3.1290816434117823,0.9266068390226809
3,040
Glycerophospholipid biosynthesis
17
32
2.423887
0.015355
Q9HBU6,Q9NQZ5,Q8IV08,Q96N66,Q9NP80,O14735,Q8NCC3,Q9NPH0,Q9UG56,P40939,Q7L5N7,Q9NUQ2,P35790,Q53H12,P43304,Q86UL3,Q6P1A2
Processes and pathways
Reactome Pathways
msigdb_reactome
96,65,291,197,134,446,17,18,247,212,628,153,435,587,532,483,61
446,2108,1212,1825,1407,435,212,532,2265,1457,2585,1349,587,61,628,483,291,17,659,1015,1325,197,902,1857,2317,96,755,134,18,65,153,247
0.7464317890494901,-0.44132700120879625,0.06721945624007275,-0.2753114513174612,-0.04505853001654639,0.7666671108145032,1.3872343728517897,0.6238439182752883,-0.5381064762809528,-0.06773581807620718,-0.7865919937038053,7.238315672777529e-05,0.5617747326313666,2.661739823625172,0.5200999892947062,0.7057948318332095,1.1025840074529036,3.6025751739028236,0.4991726460209864,0.19959848010973788,0.022527332531551376,1.4614265634176216,0.28648432191911377,-0.2753114513174612,-0.5625275930863287,2.185089936053244,0.41485233449395625,1.804742035797999,3.573673225714372,2.6136277930918457,1.6978944756633867,1.2746191459726386
3,040
Electron transport
12
44
2.419949
0.015523
Q86Y39,Q9UDW1,Q9H1E5,Q96CU9,P03886,O43676,O43396,O96000,O75438,O75306,O43169,O14949
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
164,71,140,108,47,269,277,311,240,57,29,190
1028,190,29,277,269,1450,57,240,785,473,2550,619,311,1033,47,2257,2222,1640,1709,1551,581,360,2911,2647,647,2303,2767,1987,847,1720,2657,1354,2233,482,164,108,611,927,140,954,1438,906,71,2844
0.17770858414888777,1.4798666078148721,3.2046775288036393,1.160355161006498,1.179516459667705,-0.06773581807620718,2.67771886764343,1.2746191459726386,0.3723187418842105,0.7057948318332095,-0.7613038169053663,0.5200999892947062,1.0248732054561662,0.17770858414888777,2.929545586146746,-0.5381064762809528,-0.5137767760722269,-0.15920642504678456,-0.20540847316623317,-0.11331744141047409,0.5617747326313666,0.9266068390226809,-1.3429937902950162,-0.8374742177649565,0.4991726460209864,-0.5625275930863287,-0.9926509483185962,-0.36966757047407667,0.32953079791525924,-0.20540847316623317,-0.8374742177649565,7.238315672777529e-05,-0.5137767760722269,0.7057948318332095,1.6077673117097622,1.9797856725780703,0.5409671955712879,0.2648627970741298,1.7692815441810628,0.24317501987691698,-0.04505853001654639,0.28648432191911377,2.5652503504888915,-1.1250106483577362
3,040
Muscle abnormality related to mitochondrial dysfunction
13
37
2.381863
0.017225
Q9BSH4,Q86Y39,Q9NP80,Q9UBX3,P00846,Q96CU9,P03886,Q9NPL8,O43676,Q9Y2R0,O96000,O75306,Q9BUK6
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
325,164,134,232,73,108,47,441,269,86,311,57,126
1028,269,989,1450,57,785,1370,311,1033,73,47,789,1709,2911,1555,1987,449,2584,587,164,1049,1808,108,596,325,2632,126,1623,134,441,1438,1483,232,86,1401,1732,2844
0.17770858414888777,1.179516459667705,0.19959848010973788,-0.06773581807620718,2.67771886764343,0.3723187418842105,-0.022456018591835984,1.0248732054561662,0.17770858414888777,2.5328492892945635,2.929545586146746,0.3723187418842105,-0.20540847316623317,-1.3429937902950162,-0.11331744141047409,-0.36966757047407667,0.7464317890494901,-0.7865919937038053,0.5617747326313666,1.6077673117097622,0.17770858414888777,-0.2519294648126461,1.9797856725780703,0.5617747326313666,1.005321354697109,-0.8119817547252068,1.8752060118084188,-0.13622316069244658,1.804742035797999,0.7666671108145032,-0.04505853001654639,-0.06773581807620718,1.3123375484934685,2.352447611616457,-0.022456018591835984,-0.20540847316623317,-1.1250106483577362
3,040
Electron transport chain oxphos system in mitochondria
11
47
2.362541
0.01815
Q9UDW1,P00846,P03886,Q7KZN9,O75964,P14406,O43676,O96000,O75438,O75306,O14949
Processes and pathways
WikiPathways
msigdb_wp
71,73,47,178,79,19,269,311,240,57,190
1028,1132,190,269,1450,57,240,785,559,1666,79,473,2550,311,1033,73,47,1170,694,2919,789,580,762,19,1640,1709,1174,1551,360,913,2556,2911,2647,647,791,2921,1987,847,741,1412,2657,1354,178,71,1486,2844,837
0.17770858414888777,0.11162542503352747,1.4798666078148721,1.179516459667705,-0.06773581807620718,2.67771886764343,1.2746191459726386,0.3723187418842105,0.582523062344913,-0.18226795279044486,2.4020229552889067,0.7057948318332095,-0.7613038169053663,1.0248732054561662,0.17770858414888777,2.5328492892945635,2.929545586146746,0.0894578986082535,0.4571356471709892,-1.3708103994508807,0.3723187418842105,0.5617747326313666,0.39361707513132105,3.5010292750882246,-0.15920642504678456,-0.20540847316623317,0.0894578986082535,-0.11331744141047409,0.9266068390226809,0.2648627970741298,-0.7613038169053663,-1.3429937902950162,-0.8374742177649565,0.4991726460209864,0.3723187418842105,-1.3708103994508807,-0.36966757047407667,0.32953079791525924,0.41485233449395625,-0.04505853001654639,-0.8374742177649565,7.238315672777529e-05,1.553202877356439,2.5652503504888915,-0.06773581807620718,-1.1250106483577362,0.3509568225038281
3,040
Downstream signaling events of b cell receptor bcr
9
43
2.35748
0.018399
P49721,P62942,P28072,P49720,Q99436,P20618,P28070,P60900,P28074
Processes and pathways
Reactome Pathways
msigdb_reactome
32,130,260,133,367,138,177,50,242
1734,839,1663,1293,2721,1068,373,1094,991,2146,138,2068,844,621,1072,1106,177,260,242,2468,1834,794,133,32,1000,1598,50,916,1798,1799,2081,130,771,1267,917,2156,1921,1270,550,367,2010,756,1489
-0.22862872657474756,0.32953079791525924,-0.18226795279044486,0.022527332531551376,-0.9404941645246845,0.1557501687575436,0.9067996292104508,0.13372264733385414,0.19959848010973788,-0.4653879408758077,1.7692815441810628,-0.4173538681027949,0.32953079791525924,0.5200999892947062,0.1557501687575436,0.13372264733385414,1.553202877356439,1.2176973554481503,1.2746191459726386,-0.6860379068899511,-0.2753114513174612,0.3723187418842105,1.804742035797999,3.1290816434117823,0.19959848010973788,-0.13622316069244658,2.8202460802749503,0.2648627970741298,-0.2519294648126461,-0.2519294648126461,-0.4173538681027949,1.8400495980357443,0.39361707513132105,0.04490947737153897,0.2648627970741298,-0.4653879408758077,-0.32232228259890044,0.04490947737153897,0.6032126407743291,0.9266068390226809,-0.36966757047407667,0.41485233449395625,-0.06773581807620718
3,040
Proton transmembrane transporter activity
8
38
2.3459
0.018981
Q9Y487,Q9UDW1,P00846,O75964,Q93050,O00400,P61421,Q96ES6
Functions
GO Molecular function
msigdb_gomf
99,71,73,79,144,53,152,157
53,1132,1666,79,1032,1033,73,1170,694,2257,2919,789,762,1174,993,2034,913,2556,647,791,1345,1590,2921,1596,741,1412,152,696,1648,178,2424,144,157,637,71,2176,99,1630
2.725483103215559,0.11162542503352747,-0.18226795279044486,2.4020229552889067,0.17770858414888777,0.17770858414888777,2.5328492892945635,0.0894578986082535,0.4571356471709892,-0.5381064762809528,-1.3708103994508807,0.3723187418842105,0.39361707513132105,0.0894578986082535,0.19959848010973788,-0.3934676753169731,0.2648627970741298,-0.7613038169053663,0.4991726460209864,0.3723187418842105,7.238315672777529e-05,-0.13622316069244658,-1.3708103994508807,-0.13622316069244658,0.41485233449395625,-0.04505853001654639,1.6978944756633867,0.4571356471709892,-0.15920642504678456,1.553202877356439,-0.6363489276465712,1.733666307759838,1.6619641606074178,0.5200999892947062,2.5652503504888915,-0.4653879408758077,2.1172115046276017,-0.13622316069244658
3,040
Proteasome degradation
8
41
2.333964
0.019598
P49721,P28072,P49720,P20618,P28070,P60900,P28074,P16104
Processes and pathways
WikiPathways
msigdb_wp
32,260,133,138,177,50,242,28
839,1663,2721,1094,991,1098,1453,1406,1340,888,28,2146,138,2645,2068,844,621,1072,1106,177,260,242,2468,1834,794,133,32,1000,1598,50,916,1798,1799,2081,1267,2156,1270,367,2010,756,1489
0.32953079791525924,-0.18226795279044486,-0.9404941645246845,0.13372264733385414,0.19959848010973788,0.13372264733385414,-0.06773581807620718,-0.04505853001654639,7.238315672777529e-05,0.28648432191911377,3.249738300187642,-0.4653879408758077,1.7692815441810628,-0.8374742177649565,-0.4173538681027949,0.32953079791525924,0.5200999892947062,0.1557501687575436,0.13372264733385414,1.553202877356439,1.2176973554481503,1.2746191459726386,-0.6860379068899511,-0.2753114513174612,0.3723187418842105,1.804742035797999,3.1290816434117823,0.19959848010973788,-0.13622316069244658,2.8202460802749503,0.2648627970741298,-0.2519294648126461,-0.2519294648126461,-0.4173538681027949,0.04490947737153897,-0.4653879408758077,0.04490947737153897,0.9266068390226809,-0.36966757047407667,0.41485233449395625,-0.06773581807620718
3,040
Protease
29
77
2.325813
0.020029
O43464,P28072,P55786,P09960,Q16740,Q9NUQ7,O95630,O43847,P67812,Q96K76,Q99797,Q8TCT8,Q4J6C6,O75844,Q9BYT8,Q8TCT9,P48147,Q9HB40,Q99436,P53582,Q9UIQ6,Q96FW1,Q5JRX3,P52888,Q9NZ08,P28074,Q92905,Q96E52,Q92643
Functions
Protein Atlas Molecular function
protein_atlas_molecular_function
503,260,6,259,523,408,26,159,163,37,54,194,322,69,487,347,220,103,367,107,501,366,362,361,119,242,376,124,508
1367,1293,2107,503,159,1299,69,2948,560,26,2065,259,1101,2032,1036,1708,1214,260,242,2673,889,1589,2469,1263,1645,220,2470,1797,361,939,107,2944,2614,6,795,163,3034,2861,1472,1042,523,322,362,1114,2088,774,1390,194,347,508,376,1234,923,124,366,1121,37,2536,2009,367,2894,1394,54,487,2242,1244,2397,542,103,862,1726,408,1482,119,501,1365,1446
-0.022456018591835984,0.022527332531551376,-0.44132700120879625,0.6649333439702259,1.6439389719907391,0.022527332531551376,2.5652503504888915,-1.483411892468181,0.582523062344913,3.294580100112679,-0.4173538681027949,1.2176973554481503,0.13372264733385414,-0.3934676753169731,0.17770858414888777,-0.20540847316623317,0.06721945624007275,1.2176973554481503,1.2746191459726386,-0.8630705208373466,0.28648432191911377,-0.13622316069244658,-0.6860379068899511,0.04490947737153897,-0.15920642504678456,1.3498751782655338,-0.6860379068899511,-0.2519294648126461,0.9266068390226809,0.24317501987691698,2.014354642413987,-1.4550577626394943,-0.8119817547252068,5.13606374568797,0.3723187418842105,1.6077673117097622,-3.9180307769305425,-1.1787698895200653,-0.06773581807620718,0.17770858414888777,0.6444173395953164,1.005321354697109,0.9266068390226809,0.13372264733385414,-0.4173538681027949,0.39361707513132105,-0.022456018591835984,1.4798666078148721,0.9660662342487973,0.6649333439702259,0.9067996292104508,0.06721945624007275,0.2648627970741298,1.8752060118084188,0.9266068390226809,0.13372264733385414,3.0528553449126603,-0.7361161262584145,-0.36966757047407667,0.9266068390226809,-1.2603180196379737,-0.022456018591835984,2.725483103215559,0.7057948318332095,-0.5137767760722269,0.06721945624007275,-0.6116478542652064,0.6238439182752883,2.100156093249775,0.32953079791525924,-0.20540847316623317,0.8270453312183077,-0.06773581807620718,1.8927280853424016,0.6853923652184316,7.238315672777529e-05,-0.04505853001654639
3,040
Microbody
18
51
2.317834
0.020458
P08670,Q8N4Q0,Q9NP80,P40855,Q8TB36,Q9NR77,O14734,Q9GZY8,Q9BY49,P51648,Q6YN16,O00429,O43808,O75381,Q96CN7,O15254,Q9UKU0,P48735
Localization
GO Cellular component
msigdb_gocc
256,1,134,388,391,11,299,368,498,244,507,489,461,181,219,120,409,193
1366,489,299,120,461,1586,737,181,2521,962,1548,256,2144,1502,1036,1671,622,2872,2466,1075,388,193,2975,244,2195,2500,3029,1567,521,2589,1609,507,2695,1849,1,1278,1052,391,1810,219,1280,2282,498,368,134,11,2516,1696,409,2137,1899
-0.022456018591835984,0.6853923652184316,1.063827239756187,1.8752060118084188,0.7261411670729521,-0.13622316069244658,0.41485233449395625,1.5349318668753111,-0.7361161262584145,0.22142043515709942,-0.11331744141047409,1.2367175827335657,-0.4653879408758077,-0.09048855958396525,0.17770858414888777,-0.18226795279044486,0.5200999892947062,-1.2058298802981928,-0.6860379068899511,0.1557501687575436,0.867028329570998,1.4798666078148721,-1.6273031895761814,1.2746191459726386,-0.4895375675230639,-0.7110278429358069,-2.4411929362429676,-0.11331744141047409,0.6444173395953164,-0.7865919937038053,-0.13622316069244658,0.6649333439702259,-0.888771822686556,-0.2753114513174612,5.981212405325915,0.04490947737153897,0.17770858414888777,0.867028329570998,-0.2519294648126461,1.3685769357877944,0.04490947737153897,-0.5381064762809528,0.6853923652184316,0.9266068390226809,1.804742035797999,3.9148541626840703,-0.7110278429358069,-0.18226795279044486,0.8270453312183077,-0.44132700120879625,-0.2987754614191971
3,040
Metalloendopeptidase activity
9
15
2.317625
0.02047
O75844,Q5JRX3,P52888,P22695,Q99797,Q10713,Q92905,Q96E52,O43847
Functions
GO Molecular function
msigdb_gomf
69,362,361,360,54,215,376,124,159
159,1299,69,1036,360,1263,361,215,362,376,124,2009,54,487,1365
1.6439389719907391,0.022527332531551376,2.5652503504888915,0.17770858414888777,0.9266068390226809,0.04490947737153897,0.9266068390226809,1.3685769357877944,0.9266068390226809,0.9067996292104508,1.8752060118084188,-0.36966757047407667,2.725483103215559,0.7057948318332095,7.238315672777529e-05
3,040
Threonine type peptidase activity
7
10
2.294704
0.02175
P49721,P28072,P49720,Q99436,P20618,P28070,P28074
Functions
GO Molecular function
msigdb_gomf
32,260,133,367,138,177,242
138,1072,177,260,242,133,32,2088,367,393
1.7692815441810628,0.1557501687575436,1.553202877356439,1.2176973554481503,1.2746191459726386,1.804742035797999,3.1290816434117823,-0.4173538681027949,0.9266068390226809,0.867028329570998
3,040
Metalloprotease
12
39
2.289912
0.022026
O75844,P55786,P53582,Q5JRX3,P52888,Q9NZ08,P22695,Q99797,Q10713,O95630,Q96E52,O43847
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
69,6,107,362,361,119,360,54,215,26,124,159
1367,1293,784,159,1299,69,26,2925,1502,2032,1036,360,2673,647,1263,1000,361,107,6,215,1922,2445,362,748,774,1477,2210,376,3024,124,2536,2009,54,2813,487,1482,119,501,1365
-0.022456018591835984,0.022527332531551376,0.3723187418842105,1.6439389719907391,0.022527332531551376,2.5652503504888915,3.294580100112679,-1.3987587837144049,-0.09048855958396525,-0.3934676753169731,0.17770858414888777,0.9266068390226809,-0.8630705208373466,0.4991726460209864,0.04490947737153897,0.19959848010973788,0.9266068390226809,2.014354642413987,5.13606374568797,1.3685769357877944,-0.32232228259890044,-0.6611452764022983,0.9266068390226809,0.41485233449395625,0.39361707513132105,-0.06773581807620718,-0.4895375675230639,0.9067996292104508,-2.2754398786534136,1.8752060118084188,-0.7361161262584145,-0.36966757047407667,2.725483103215559,-1.0452522464160021,0.7057948318332095,-0.06773581807620718,1.8927280853424016,0.6853923652184316,7.238315672777529e-05
3,040
Phospholipid metabolic process
34
79
2.289854
0.02203
Q8NF37,Q5H8A4,Q9NP80,P19174,Q8NCC3,Q9NPH0,Q8WTV0,Q9NUQ2,Q969N2,Q86YN1,Q96PE3,O15269,Q86SQ9,Q96S52,Q8N2K0,P35790,Q05655,O15270,Q6P1A2,Q96N66,Q8TBX8,Q08AM6,O14735,Q99623,Q9BTU6,P40939,Q10713,P42356,Q86UL3,Q9HBU6,Q9UG56,Q7L5N7,Q9NXE4,Q92643
Processes and pathways
GO Biological process
msigdb_gobp
659,655,134,519,17,18,22,153,406,31,35,666,428,438,304,435,314,689,61,197,594,451,446,725,468,212,215,716,483,96,247,628,378,508
1901,1131,446,666,689,1701,1634,962,1548,1212,1739,1825,3026,1667,1214,519,1828,935,435,1218,212,716,2227,2265,2981,943,1801,2505,314,451,215,1386,1567,2589,655,1609,61,628,428,483,31,1047,304,17,1052,659,1613,594,22,1015,1810,1325,508,406,197,35,438,2011,725,1857,468,1436,2317,2096,96,755,134,18,1399,1285,153,1628,378,2245,907,247,1485,1815,2718
-0.32232228259890044,0.11162542503352747,0.7464317890494901,0.4781846919533493,0.4571356471709892,-0.20540847316623317,-0.15920642504678456,0.22142043515709942,-0.11331744141047409,0.06721945624007275,-0.22862872657474756,-0.2753114513174612,-2.374364065437545,-0.18226795279044486,0.06721945624007275,0.6444173395953164,-0.2753114513174612,0.24317501987691698,0.7666671108145032,0.06721945624007275,1.3872343728517897,0.43602502551870426,-0.5137767760722269,-0.5381064762809528,-1.6565192297626519,0.24317501987691698,-0.2519294648126461,-0.7110278429358069,1.0248732054561662,0.7464317890494901,1.3685769357877944,-0.022456018591835984,-0.11331744141047409,-0.7865919937038053,0.4991726460209864,-0.13622316069244658,2.661739823625172,0.5200999892947062,0.7868475404440897,0.7057948318332095,3.174513917781018,0.17770858414888777,1.063827239756187,3.6025751739028236,0.17770858414888777,0.4991726460209864,-0.13622316069244658,0.5617747326313666,3.4278200746104854,0.19959848010973788,-0.2519294648126461,0.022527332531551376,0.6649333439702259,0.8270453312183077,1.4614265634176216,3.0834224304076256,0.7666671108145032,-0.36966757047407667,0.43602502551870426,-0.2753114513174612,0.7261411670729521,-0.04505853001654639,-0.5625275930863287,-0.4173538681027949,2.185089936053244,0.41485233449395625,1.804742035797999,3.573673225714372,-0.022456018591835984,0.04490947737153897,1.6978944756633867,-0.13622316069244658,0.9067996292104508,-0.5137767760722269,0.28648432191911377,1.2746191459726386,-0.06773581807620718,-0.2519294648126461,-0.9145793033142863
3,040
Tetrapyrrole binding
11
16
2.267247
0.023375
Q9H7Z7,Q6UW02,Q96EY8,P30519,Q9NRV9,Q16850,Q7KZN9,P09601,Q8WUJ1,O43169,O15173
Functions
GO Molecular function
msigdb_gomf
386,102,188,10,267,76,178,121,58,29,158
410,158,29,2257,121,2113,10,650,76,102,178,58,188,675,386,267
0.8069734811215312,1.6439389719907391,3.2046775288036393,-0.5381064762809528,1.8752060118084188,-0.44132700120879625,3.9982964007313817,0.4991726460209864,2.484020507983507,2.100156093249775,1.553202877356439,2.67771886764343,1.4982639954012558,0.4781846919533493,0.8869402512163685,1.1986304188795078
3,040
Endoplasmic reticulum golgi intermediate compartment
10
51
2.254941
0.024137
O15260,P80303,O95070,P56962,P24390,O15155,Q13190,Q8N511,Q9Y282,Q96RQ1
Localization
GO Cellular component
msigdb_gocc
166,136,295,320,43,141,142,148,24,89
1819,141,1207,166,868,1822,295,530,2145,43,1215,1983,2305,1222,2582,1223,848,2944,1379,320,892,136,1078,425,566,345,944,142,2275,1843,2962,1353,1082,1116,148,1528,900,1689,808,89,703,1621,904,2434,2285,1485,24,782,1335,1494,1785
-0.2753114513174612,1.7514933839084825,0.06721945624007275,1.5896203443681522,0.30804014209060904,-0.2753114513174612,1.0832301121348886,0.6238439182752883,-0.4653879408758077,2.975984123826262,0.06721945624007275,-0.36966757047407667,-0.5625275930863287,0.06721945624007275,-0.7865919937038053,0.06721945624007275,0.32953079791525924,-1.4550577626394943,-0.022456018591835984,1.005321354697109,0.28648432191911377,1.7870310188063467,0.1557501687575436,0.7868475404440897,0.582523062344913,0.9660662342487973,0.24317501987691698,1.7514933839084825,-0.5381064762809528,-0.2753114513174612,-1.511904869971841,7.238315672777529e-05,0.1557501687575436,0.13372264733385414,1.715800083261279,-0.09048855958396525,0.28648432191911377,-0.18226795279044486,0.3723187418842105,2.285898261326629,0.4571356471709892,-0.13622316069244658,0.28648432191911377,-0.6363489276465712,-0.5381064762809528,-0.06773581807620718,3.3688375992261888,0.39361707513132105,0.022527332531551376,-0.06773581807620718,-0.22862872657474756
3,040
Metalloprotease
12
28
2.254382
0.024172
O75844,P55786,P09960,Q5JRX3,P52888,Q9NZ08,Q99797,Q9BYT8,Q92905,O95630,Q96E52,O43847
Functions
Protein Atlas Molecular function
protein_atlas_molecular_function
69,6,259,362,361,119,54,487,376,26,124,159
1293,159,1299,69,2948,26,259,2032,1036,1708,1263,361,6,362,774,376,124,2536,2009,54,487,1244,862,1726,1482,119,501,1365
0.022527332531551376,1.6439389719907391,0.022527332531551376,2.5652503504888915,-1.483411892468181,3.294580100112679,1.2176973554481503,-0.3934676753169731,0.17770858414888777,-0.20540847316623317,0.04490947737153897,0.9266068390226809,5.13606374568797,0.9266068390226809,0.39361707513132105,0.9067996292104508,1.8752060118084188,-0.7361161262584145,-0.36966757047407667,2.725483103215559,0.7057948318332095,0.06721945624007275,0.32953079791525924,-0.20540847316623317,-0.06773581807620718,1.8927280853424016,0.6853923652184316,7.238315672777529e-05
3,040
Apical part of cell
10
52
2.243229
0.024882
P36551,P41208,P08183,O15020,P41440,P61421,Q99797,Q99808,Q86UE4,P53985
Localization
GO Cellular component
msigdb_gocc
288,413,255,317,146,152,54,90,355,95
2105,930,1818,317,1940,1297,1300,787,1169,1373,255,1793,2255,2256,912,2298,1909,1104,933,993,2034,1306,1752,1553,1345,288,1590,413,146,1596,95,1179,1380,1917,152,2042,969,1229,1230,2620,1651,427,355,2591,1394,54,90,1583,2284,1288,2518,1205
-0.44132700120879625,0.24317501987691698,-0.2753114513174612,1.005321354697109,-0.3459527147544944,0.022527332531551376,0.022527332531551376,0.3723187418842105,0.0894578986082535,-0.022456018591835984,1.2367175827335657,-0.2519294648126461,-0.5381064762809528,-0.5381064762809528,0.2648627970741298,-0.5625275930863287,-0.32232228259890044,0.13372264733385414,0.24317501987691698,0.19959848010973788,-0.3934676753169731,0.022527332531551376,-0.22862872657474756,-0.11331744141047409,7.238315672777529e-05,1.1025840074529036,-0.13622316069244658,0.8069734811215312,1.715800083261279,-0.13622316069244658,2.185089936053244,0.0894578986082535,-0.022456018591835984,-0.32232228259890044,1.6978944756633867,-0.3934676753169731,0.22142043515709942,0.06721945624007275,0.06721945624007275,-0.8119817547252068,-0.15920642504678456,0.7868475404440897,0.9463622517624058,-0.7865919937038053,-0.022456018591835984,2.725483103215559,2.269179628829763,-0.11331744141047409,-0.5381064762809528,0.04490947737153897,-0.7110278429358069,0.0894578986082535
3,040
Switching of origins to a post replicative state
11
55
2.228428
0.025852
P49721,Q9Y619,P28072,P49720,Q9UJX2,P20618,P28070,P60900,P28074,Q96DE5,Q9UJX3
Processes and pathways
Reactome Pathways
msigdb_reactome
32,185,260,133,233,138,177,50,242,281,328
839,1663,1293,2721,1094,991,2146,138,994,1710,2068,844,621,1072,1106,177,260,242,1217,2301,1642,2035,2468,1834,794,133,32,2149,1000,1598,50,916,1798,1799,2081,771,1267,2156,2420,1921,1387,1270,625,550,281,367,2010,1967,955,233,328,1290,756,1489,185
0.32953079791525924,-0.18226795279044486,0.022527332531551376,-0.9404941645246845,0.13372264733385414,0.19959848010973788,-0.4653879408758077,1.7692815441810628,0.19959848010973788,-0.20540847316623317,-0.4173538681027949,0.32953079791525924,0.5200999892947062,0.1557501687575436,0.13372264733385414,1.553202877356439,1.2176973554481503,1.2746191459726386,0.06721945624007275,-0.5625275930863287,-0.15920642504678456,-0.3934676753169731,-0.6860379068899511,-0.2753114513174612,0.3723187418842105,1.804742035797999,3.1290816434117823,-0.4653879408758077,0.19959848010973788,-0.13622316069244658,2.8202460802749503,0.2648627970741298,-0.2519294648126461,-0.2519294648126461,-0.4173538681027949,0.39361707513132105,0.04490947737153897,-0.4653879408758077,-0.6363489276465712,-0.32232228259890044,-0.022456018591835984,0.04490947737153897,0.5200999892947062,0.6032126407743291,1.160355161006498,0.9266068390226809,-0.36966757047407667,-0.3459527147544944,0.24317501987691698,1.3123375484934685,1.005321354697109,0.04490947737153897,0.41485233449395625,-0.06773581807620718,1.5166189935414305
3,040
Respirasome
13
42
2.224743
0.026098
Q86Y39,Q9UDW1,Q96CU9,P03886,Q7KZN9,P14406,O43676,P22695,O96000,O75438,O75306,Q6DKK2,O14949
Localization
GO Cellular component
msigdb_gocc
164,71,108,47,178,19,269,360,311,240,57,482,190
1028,1132,190,269,1450,57,240,785,473,2550,311,1033,47,2257,2919,762,19,1640,1709,1174,1551,360,2911,2647,647,1987,847,1648,2657,1354,482,178,164,108,2754,927,1438,906,71,886,1732,2844
0.17770858414888777,0.11162542503352747,1.4798666078148721,1.179516459667705,-0.06773581807620718,2.67771886764343,1.2746191459726386,0.3723187418842105,0.7057948318332095,-0.7613038169053663,1.0248732054561662,0.17770858414888777,2.929545586146746,-0.5381064762809528,-1.3708103994508807,0.39361707513132105,3.5010292750882246,-0.15920642504678456,-0.20540847316623317,0.0894578986082535,-0.11331744141047409,0.9266068390226809,-1.3429937902950162,-0.8374742177649565,0.4991726460209864,-0.36966757047407667,0.32953079791525924,-0.15920642504678456,-0.8374742177649565,7.238315672777529e-05,0.7057948318332095,1.553202877356439,1.6077673117097622,1.9797856725780703,-0.9665176304872712,0.2648627970741298,-0.04505853001654639,0.28648432191911377,2.5652503504888915,0.30804014209060904,-0.20540847316623317,-1.1250106483577362
3,040
Ion transport
13
51
2.224098
0.026142
P51798,P45880,Q9Y487,Q9Y277,Q9H4I9,P00846,Q9P246,Q8TDW0,O75964,Q93050,Q9BPX6,P21796,P61421
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
477,192,99,394,200,73,370,236,79,144,51,211,152
2519,1666,79,1032,786,73,1169,694,2111,764,933,993,2034,211,913,2556,791,1345,1590,192,2921,1596,477,1179,1380,741,1412,152,800,2276,1353,548,1848,496,2209,1886,236,144,1616,51,2537,1241,2904,200,370,2176,1585,394,99,1630,1205
-0.7361161262584145,-0.18226795279044486,2.4020229552889067,0.17770858414888777,0.3723187418842105,2.5328492892945635,0.0894578986082535,0.4571356471709892,-0.44132700120879625,0.39361707513132105,0.24317501987691698,0.19959848010973788,-0.3934676753169731,1.3872343728517897,0.2648627970741298,-0.7613038169053663,0.3723187418842105,7.238315672777529e-05,-0.13622316069244658,1.4798666078148721,-1.3708103994508807,-0.13622316069244658,0.7057948318332095,0.0894578986082535,-0.022456018591835984,0.41485233449395625,-0.04505853001654639,1.6978944756633867,0.3723187418842105,-0.5381064762809528,7.238315672777529e-05,0.6032126407743291,-0.2753114513174612,0.6853923652184316,-0.4895375675230639,-0.2987754614191971,1.2935010918758008,1.733666307759838,-0.13622316069244658,2.8202460802749503,-0.7361161262584145,0.06721945624007275,-1.2877492256217191,1.4429435920810105,0.9266068390226809,-0.4653879408758077,-0.11331744141047409,0.867028329570998,2.1172115046276017,-0.13622316069244658,0.0894578986082535
3,040
Hedgehog off state
19
48
2.222658
0.026239
P63208,P28072,P49720,P20618,Q9BUF5,P49721,Q92530,P48556,P28070,P60900,P04350,P25787,P10644,Q9UL46,Q99436,Q96J02,P28074,P25788,P48729
Processes and pathways
Reactome Pathways
msigdb_reactome
771,260,133,138,676,32,550,794,177,50,561,844,343,756,367,633,242,621,383
839,1663,1293,2721,1094,991,561,343,1873,2146,138,2068,844,621,1072,1106,177,260,242,2468,1834,794,383,133,32,1410,1000,1598,50,916,1798,1799,2081,771,1111,1267,2156,1921,1270,550,633,367,2010,676,1533,756,1489,1444
0.32953079791525924,-0.18226795279044486,0.022527332531551376,-0.9404941645246845,0.13372264733385414,0.19959848010973788,0.582523062344913,0.9660662342487973,-0.2987754614191971,-0.4653879408758077,1.7692815441810628,-0.4173538681027949,0.32953079791525924,0.5200999892947062,0.1557501687575436,0.13372264733385414,1.553202877356439,1.2176973554481503,1.2746191459726386,-0.6860379068899511,-0.2753114513174612,0.3723187418842105,0.8869402512163685,1.804742035797999,3.1290816434117823,-0.04505853001654639,0.19959848010973788,-0.13622316069244658,2.8202460802749503,0.2648627970741298,-0.2519294648126461,-0.2519294648126461,-0.4173538681027949,0.39361707513132105,0.13372264733385414,0.04490947737153897,-0.4653879408758077,-0.32232228259890044,0.04490947737153897,0.6032126407743291,0.5200999892947062,0.9266068390226809,-0.36966757047407667,0.4781846919533493,-0.09048855958396525,0.41485233449395625,-0.06773581807620718,-0.04505853001654639
3,040
Intrinsic component of organelle membrane
60
139
2.22185
0.026293
P57088,Q5H8A4,Q13505,O43752,O60830,Q99595,Q8N8Q8,Q8TB36,Q16799,O15155,Q96A33,Q15629,Q969N2,Q9Y282,O43826,O14925,L0R6Q1,Q86YN1,Q6P4A7,Q5T9L3,Q9NZ01,Q03518,P57105,O95563,Q9BUN8,O95070,Q15006,O94901,Q96S52,Q9Y4P3,Q9BPX6,O15118,Q9H3K2,Q9BUR5,O75880,O75431,Q8TCT8,O75844,Q15070,Q9BWH2,Q9H4I9,Q14739,Q9P035,Q5XKP0,Q15388,O43808,Q9Y2R0,Q53H12,Q8TCT9,Q86XL3,Q9NQC3,Q9BTV4,Q9GZY8,Q9Y512,Q8TB61,Q9UG56,O60499,O95470,Q92643,O43505
Localization
GO Cellular component
msigdb_gocc
384,655,3,132,5,7,264,391,390,141,541,147,406,24,151,282,528,31,289,34,555,425,38,167,168,295,426,422,438,444,51,176,572,184,559,558,194,69,196,598,200,335,339,466,463,461,86,587,347,94,226,635,368,248,629,247,239,380,508,249
1130,528,708,282,176,1543,141,1207,1701,1821,249,132,461,1209,151,239,5,737,558,69,559,1097,1031,422,295,1211,380,167,786,1098,1453,888,789,1504,933,2745,1215,1105,2746,2845,1263,1715,1039,1559,1223,384,38,1919,850,800,696,425,1513,3007,3,1995,335,426,853,196,3028,463,147,1720,390,1044,587,655,1474,1570,34,466,289,2448,1010,1572,2160,94,1012,31,1771,1611,1084,1050,2424,723,264,2004,2209,391,629,194,347,1810,508,406,541,438,1058,7,51,1724,635,662,168,184,598,368,572,2096,200,1157,1021,1582,1245,2487,226,1159,2217,810,811,555,339,1661,908,247,682,1161,1585,24,86,1493,444,1365,248,1093,1899,707,837
0.11162542503352747,0.6238439182752883,0.43602502551870426,1.1411462025905137,1.553202877356439,-0.11331744141047409,1.7514933839084825,0.06721945624007275,-0.20540847316623317,-0.2753114513174612,1.2556914107011634,1.804742035797999,0.7261411670729521,0.06721945624007275,1.6978944756633867,1.2746191459726386,5.283619928591475,0.41485233449395625,0.582523062344913,2.5652503504888915,0.582523062344913,0.13372264733385414,0.17770858414888777,0.7868475404440897,1.0832301121348886,0.06721945624007275,0.8869402512163685,1.5896203443681522,0.3723187418842105,0.13372264733385414,-0.06773581807620718,0.28648432191911377,0.3723187418842105,-0.09048855958396525,0.24317501987691698,-0.9665176304872712,0.06721945624007275,0.13372264733385414,-0.9665176304872712,-1.151830630256655,0.04490947737153897,-0.20540847316623317,0.17770858414888777,-0.11331744141047409,0.06721945624007275,0.8869402512163685,3.037533168359685,-0.32232228259890044,0.32953079791525924,0.3723187418842105,0.4571356471709892,0.7868475404440897,-0.09048855958396525,-1.9265112413148566,5.7379702431047095,-0.36966757047407667,0.9857191490793755,0.7868475404440897,0.32953079791525924,1.4614265634176216,-2.4076910053251255,0.7261411670729521,1.715800083261279,-0.20540847316623317,0.867028329570998,0.17770858414888777,0.5617747326313666,0.4991726460209864,-0.06773581807620718,-0.11331744141047409,3.113887273327359,0.7261411670729521,1.1025840074529036,-0.6611452764022983,0.19959848010973788,-0.11331744141047409,-0.4653879408758077,2.2019746742666584,0.19959848010973788,3.174513917781018,-0.22862872657474756,-0.13622316069244658,0.1557501687575436,0.17770858414888777,-0.6363489276465712,0.43602502551870426,1.1986304188795078,-0.36966757047407667,-0.4895375675230639,0.867028329570998,0.5200999892947062,1.4798666078148721,0.9660662342487973,-0.2519294648126461,0.6649333439702259,0.8270453312183077,0.6238439182752883,0.7666671108145032,0.17770858414888777,4.44501076876835,2.8202460802749503,-0.20540847316623317,0.5200999892947062,0.4991726460209864,1.5896203443681522,1.5166189935414305,0.5617747326313666,0.9266068390226809,0.582523062344913,-0.4173538681027949,1.4429435920810105,0.11162542503352747,0.19959848010973788,-0.11331744141047409,0.06721945624007275,-0.6860379068899511,1.3311288127114365,0.11162542503352747,-0.4895375675230639,0.3723187418842105,0.3723187418842105,0.6032126407743291,0.9857191490793755,-0.15920642504678456,0.28648432191911377,1.2746191459726386,0.4781846919533493,0.11162542503352747,-0.11331744141047409,3.3688375992261888,2.352447611616457,-0.06773581807620718,0.7666671108145032,7.238315672777529e-05,1.2746191459726386,0.1557501687575436,-0.2987754614191971,0.4571356471709892,0.3509568225038281
3,040
Abc transporter disorders
9
41
2.211298
0.027015
P49721,P28072,P49720,Q9BUN8,P20618,Q9UBV2,P28070,P60900,P28074
Processes and pathways
Reactome Pathways
msigdb_reactome
32,260,133,168,138,209,177,50,242
839,1663,1293,2721,1094,2325,991,1636,2146,138,2068,844,621,1072,1106,177,260,242,2468,1834,794,133,32,1000,1598,2197,50,916,1798,1799,2081,1267,2156,1270,550,367,2010,168,209,756,1489
0.32953079791525924,-0.18226795279044486,0.022527332531551376,-0.9404941645246845,0.13372264733385414,-0.5870410669585505,0.19959848010973788,-0.15920642504678456,-0.4653879408758077,1.7692815441810628,-0.4173538681027949,0.32953079791525924,0.5200999892947062,0.1557501687575436,0.13372264733385414,1.553202877356439,1.2176973554481503,1.2746191459726386,-0.6860379068899511,-0.2753114513174612,0.3723187418842105,1.804742035797999,3.1290816434117823,0.19959848010973788,-0.13622316069244658,-0.4895375675230639,2.8202460802749503,0.2648627970741298,-0.2519294648126461,-0.2519294648126461,-0.4173538681027949,0.04490947737153897,-0.4653879408758077,0.04490947737153897,0.6032126407743291,0.9266068390226809,-0.36966757047407667,1.5896203443681522,1.405847774017092,0.41485233449395625,-0.06773581807620718
3,040
Defective cftr causes cystic fibrosis
9
41
2.211298
0.027015
P49721,P28072,P49720,Q9BUN8,P20618,Q9UBV2,P28070,P60900,P28074
Processes and pathways
Reactome Pathways
msigdb_reactome
32,260,133,168,138,209,177,50,242
839,1663,1293,2721,1094,2325,991,1636,2146,138,2068,844,621,1072,1106,177,260,242,2468,1834,794,133,32,1000,1598,2197,50,916,1798,1799,2081,1267,2156,1270,550,367,2010,168,209,756,1489
0.32953079791525924,-0.18226795279044486,0.022527332531551376,-0.9404941645246845,0.13372264733385414,-0.5870410669585505,0.19959848010973788,-0.15920642504678456,-0.4653879408758077,1.7692815441810628,-0.4173538681027949,0.32953079791525924,0.5200999892947062,0.1557501687575436,0.13372264733385414,1.553202877356439,1.2176973554481503,1.2746191459726386,-0.6860379068899511,-0.2753114513174612,0.3723187418842105,1.804742035797999,3.1290816434117823,0.19959848010973788,-0.13622316069244658,-0.4895375675230639,2.8202460802749503,0.2648627970741298,-0.2519294648126461,-0.2519294648126461,-0.4173538681027949,0.04490947737153897,-0.4653879408758077,0.04490947737153897,0.6032126407743291,0.9266068390226809,-0.36966757047407667,1.5896203443681522,1.405847774017092,0.41485233449395625,-0.06773581807620718
3,040
Runx1 regulates transcription of genes involved in differentiation of hscs
8
40
2.208311
0.027223
P49721,Q03164,P49720,P20618,P28070,P60900,P28074,P16104
Processes and pathways
Reactome Pathways
msigdb_reactome
32,223,133,138,177,50,242,28
839,1663,1293,2721,1094,991,28,2146,138,2068,844,621,1072,1106,177,260,242,2468,1834,794,133,32,1000,1598,50,916,1798,1799,2081,2805,223,1267,2156,1270,550,633,367,2010,756,1489
0.32953079791525924,-0.18226795279044486,0.022527332531551376,-0.9404941645246845,0.13372264733385414,0.19959848010973788,3.249738300187642,-0.4653879408758077,1.7692815441810628,-0.4173538681027949,0.32953079791525924,0.5200999892947062,0.1557501687575436,0.13372264733385414,1.553202877356439,1.2176973554481503,1.2746191459726386,-0.6860379068899511,-0.2753114513174612,0.3723187418842105,1.804742035797999,3.1290816434117823,0.19959848010973788,-0.13622316069244658,2.8202460802749503,0.2648627970741298,-0.2519294648126461,-0.2519294648126461,-0.4173538681027949,-1.0452522464160021,1.3311288127114365,0.04490947737153897,-0.4653879408758077,0.04490947737153897,0.6032126407743291,0.5200999892947062,0.9266068390226809,-0.36966757047407667,0.41485233449395625,-0.06773581807620718
3,040
Abnormal activity of mitochondrial respiratory chain
11
55
2.199708
0.027828
Q86Y39,Q9UBX3,Q96CU9,P03886,Q7KZN9,O43676,Q9Y2R0,O96000,O75306,Q9Y584,Q70HW3
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
164,232,108,47,178,269,86,311,57,62,63
1028,269,2220,518,1450,57,785,1370,2550,311,47,2553,762,1709,1174,1551,2911,2147,2647,1555,2373,1987,847,1915,2584,1415,2344,1354,803,1925,1272,63,178,164,1049,108,1235,2280,325,2632,1125,1623,488,441,1438,1483,906,2541,232,86,1732,1128,62,1495,2844
0.17770858414888777,1.179516459667705,-0.5137767760722269,0.6444173395953164,-0.06773581807620718,2.67771886764343,0.3723187418842105,-0.022456018591835984,-0.7613038169053663,1.0248732054561662,2.929545586146746,-0.7613038169053663,0.39361707513132105,-0.20540847316623317,0.0894578986082535,-0.11331744141047409,-1.3429937902950162,-0.4653879408758077,-0.8374742177649565,-0.11331744141047409,-0.6116478542652064,-0.36966757047407667,0.32953079791525924,-0.32232228259890044,-0.7865919937038053,-0.04505853001654639,-0.5870410669585505,7.238315672777529e-05,0.3723187418842105,-0.32232228259890044,0.04490947737153897,2.62969443108639,1.553202877356439,1.6077673117097622,0.17770858414888777,1.9797856725780703,0.06721945624007275,-0.5381064762809528,1.005321354697109,-0.8119817547252068,0.13372264733385414,-0.13622316069244658,0.7057948318332095,0.7666671108145032,-0.04505853001654639,-0.06773581807620718,0.28648432191911377,-0.7361161262584145,1.3123375484934685,2.352447611616457,-0.20540847316623317,0.13372264733385414,2.661739823625172,-0.06773581807620718,-1.1250106483577362
3,040
Cytoprotection by hmox1
14
65
2.189788
0.02854
P49721,Q9BSH4,P28072,P49720,Q8N8Q8,P20618,P30519,Q8TCT9,P28070,P60900,P28074,P09601,Q05655,Q96I36
Processes and pathways
Reactome Pathways
msigdb_reactome
32,325,260,133,264,138,10,347,177,50,242,121,314,316
839,1663,1028,1293,1132,2721,1094,1209,1133,991,559,1033,121,2919,762,2146,1407,138,1174,2068,844,621,1072,1106,177,260,242,10,2468,2304,1555,1834,794,133,32,1000,1310,1598,50,916,1798,1799,2081,771,1349,314,1267,2156,2420,1921,2477,1270,2423,539,264,347,550,316,2426,367,2010,325,756,1489,837
0.32953079791525924,-0.18226795279044486,0.17770858414888777,0.022527332531551376,0.11162542503352747,-0.9404941645246845,0.13372264733385414,0.06721945624007275,0.11162542503352747,0.19959848010973788,0.582523062344913,0.17770858414888777,1.8752060118084188,-1.3708103994508807,0.39361707513132105,-0.4653879408758077,-0.04505853001654639,1.7692815441810628,0.0894578986082535,-0.4173538681027949,0.32953079791525924,0.5200999892947062,0.1557501687575436,0.13372264733385414,1.553202877356439,1.2176973554481503,1.2746191459726386,3.9982964007313817,-0.6860379068899511,-0.5625275930863287,-0.11331744141047409,-0.2753114513174612,0.3723187418842105,1.804742035797999,3.1290816434117823,0.19959848010973788,0.022527332531551376,-0.13622316069244658,2.8202460802749503,0.2648627970741298,-0.2519294648126461,-0.2519294648126461,-0.4173538681027949,0.39361707513132105,7.238315672777529e-05,1.0248732054561662,0.04490947737153897,-0.4653879408758077,-0.6363489276465712,-0.32232228259890044,-0.6860379068899511,0.04490947737153897,-0.6363489276465712,0.6238439182752883,1.1986304188795078,0.9660662342487973,0.6032126407743291,1.0248732054561662,-0.6363489276465712,0.9266068390226809,-0.36966757047407667,1.005321354697109,0.41485233449395625,-0.06773581807620718,0.3509568225038281
3,040
metalloprotease
13
28
2.185799
0.02883
O75844,P55786,Q9BYT8,P53582,Q5JRX3,P52888,Q9NZ08,P22695,Q99797,Q10713,O95630,Q96E52,O43847
Functions
Panther Protein class
panther_protein_class
69,6,487,107,362,361,119,360,54,215,26,124,159
159,1299,69,26,2925,2032,1036,360,2673,647,1263,361,107,6,215,362,774,1477,124,2536,2009,54,487,862,1482,119,501,1365
1.6439389719907391,0.022527332531551376,2.5652503504888915,3.294580100112679,-1.3987587837144049,-0.3934676753169731,0.17770858414888777,0.9266068390226809,-0.8630705208373466,0.4991726460209864,0.04490947737153897,0.9266068390226809,2.014354642413987,5.13606374568797,1.3685769357877944,0.9266068390226809,0.39361707513132105,-0.06773581807620718,1.8752060118084188,-0.7361161262584145,-0.36966757047407667,2.725483103215559,0.7057948318332095,0.32953079791525924,-0.06773581807620718,1.8927280853424016,0.6853923652184316,7.238315672777529e-05
3,040
Clec7a dectin 1 signaling
9
48
2.181325
0.029159
P49721,P28072,P49720,Q99436,P20618,P28070,P60900,P28074,Q05655
Processes and pathways
Reactome Pathways
msigdb_reactome
32,260,133,367,138,177,50,242,314
839,1663,1293,2721,1068,373,1094,1297,991,2146,138,2068,844,621,1072,1106,177,260,242,2468,1834,794,965,133,32,1000,1598,50,2039,2076,916,1798,1799,2081,771,314,1267,917,2156,1921,1270,2126,948,550,367,2010,756,1489
0.32953079791525924,-0.18226795279044486,0.022527332531551376,-0.9404941645246845,0.1557501687575436,0.9067996292104508,0.13372264733385414,0.022527332531551376,0.19959848010973788,-0.4653879408758077,1.7692815441810628,-0.4173538681027949,0.32953079791525924,0.5200999892947062,0.1557501687575436,0.13372264733385414,1.553202877356439,1.2176973554481503,1.2746191459726386,-0.6860379068899511,-0.2753114513174612,0.3723187418842105,0.22142043515709942,1.804742035797999,3.1290816434117823,0.19959848010973788,-0.13622316069244658,2.8202460802749503,-0.3934676753169731,-0.4173538681027949,0.2648627970741298,-0.2519294648126461,-0.2519294648126461,-0.4173538681027949,0.39361707513132105,1.0248732054561662,0.04490947737153897,0.2648627970741298,-0.4653879408758077,-0.32232228259890044,0.04490947737153897,-0.44132700120879625,0.24317501987691698,0.6032126407743291,0.9266068390226809,-0.36966757047407667,0.41485233449395625,-0.06773581807620718
3,040
Ubiquitin ligase complex
11
48
2.178349
0.02938
Q9UBU6,Q92564,Q96K76,Q92990,Q9BUN8,Q9UJX2,Q9UBV2,Q9UBS8,O60566,Q96DE5,Q9UJX3
Localization
GO Cellular component
msigdb_gocc
67,4,37,429,168,233,209,110,342,281,328
342,2779,2520,711,842,1217,2076,1600,771,1182,2420,1921,1142,2477,1993,823,1007,1420,625,2346,1768,4,429,281,2056,37,457,1237,881,168,1859,1967,600,1286,2876,2433,110,67,209,556,233,328,1290,1816,2489,836,958,707
0.9660662342487973,-1.0188953886833905,-0.7361161262584145,0.43602502551870426,0.32953079791525924,0.06721945624007275,-0.4173538681027949,-0.13622316069244658,0.39361707513132105,0.0894578986082535,-0.6363489276465712,-0.32232228259890044,0.11162542503352747,-0.6860379068899511,-0.36966757047407667,0.3509568225038281,0.19959848010973788,-0.04505853001654639,0.5200999892947062,-0.5870410669585505,-0.22862872657474756,5.429167474705789,0.7868475404440897,1.160355161006498,-0.3934676753169731,3.0528553449126603,0.7464317890494901,0.06721945624007275,0.30804014209060904,1.5896203443681522,-0.2753114513174612,-0.3459527147544944,0.5617747326313666,0.04490947737153897,-1.2058298802981928,-0.6363489276465712,1.9797856725780703,2.5975316656659477,1.405847774017092,0.6032126407743291,1.3123375484934685,1.005321354697109,0.04490947737153897,-0.2519294648126461,-0.6860379068899511,0.3509568225038281,0.24317501987691698,0.4571356471709892
3,040
Endoplasmic reticulum protein containing complex
30
60
2.171841
0.029868
P62942,Q9Y5M8,Q92890,Q969N2,P46977,P07237,Q9UGP8,P67812,Q03518,O43681,Q9BUN8,Q15006,O15269,P61009,Q96S52,Q9Y679,Q8IXB1,O15270,Q9UBU6,Q14165,P13674,Q9UBV2,Q8N766,Q15041,P61619,Q8TCT9,Q9H0U3,Q6NUQ1,Q53GQ0,Q92643
Localization
GO Cellular component
msigdb_gocc
130,276,807,406,279,530,681,163,425,545,168,426,666,795,438,707,569,689,67,824,202,209,723,853,850,347,349,225,354,508
666,689,1544,1701,1821,545,1453,1406,1340,530,202,2260,1707,2370,1215,2746,1219,279,1594,999,2197,1509,795,850,1758,130,163,425,1564,824,1996,1042,426,853,1843,354,1474,225,569,1050,723,2165,879,347,508,807,406,1615,438,168,349,2096,2487,67,209,681,2103,2739,276,707
0.4781846919533493,0.4571356471709892,-0.11331744141047409,-0.20540847316623317,-0.2753114513174612,0.6032126407743291,-0.06773581807620718,-0.04505853001654639,7.238315672777529e-05,0.6238439182752883,1.4244174208729259,-0.5381064762809528,-0.20540847316623317,-0.6116478542652064,0.06721945624007275,-0.9665176304872712,0.06721945624007275,1.160355161006498,-0.13622316069244658,0.19959848010973788,-0.4895375675230639,-0.09048855958396525,0.3723187418842105,0.32953079791525924,-0.22862872657474756,1.8400495980357443,1.6077673117097622,0.7868475404440897,-0.11331744141047409,0.3509568225038281,-0.36966757047407667,0.17770858414888777,0.7868475404440897,0.32953079791525924,-0.2753114513174612,0.9463622517624058,-0.06773581807620718,1.3311288127114365,0.582523062344913,0.17770858414888777,0.43602502551870426,-0.4653879408758077,0.30804014209060904,0.9660662342487973,0.6649333439702259,0.3723187418842105,0.8270453312183077,-0.13622316069244658,0.7666671108145032,1.5896203443681522,0.9660662342487973,-0.4173538681027949,-0.6860379068899511,2.5975316656659477,1.405847774017092,0.4781846919533493,-0.4173538681027949,-0.9404941645246845,1.179516459667705,0.4571356471709892
3,040
Apc c mediated degradation of cell cycle proteins
11
53
2.169184
0.030069
P49721,P28072,P49720,Q9UJX2,P20618,P28070,P60900,O60566,P28074,Q96DE5,Q9UJX3
Processes and pathways
Reactome Pathways
msigdb_reactome
32,260,133,233,138,177,50,342,242,281,328
839,1663,1293,2721,734,1094,1736,342,991,2064,2189,2146,138,994,2068,844,621,1072,1106,177,260,242,1217,2468,1834,794,133,32,1000,2377,1598,50,916,1798,1799,2081,771,1267,2156,2420,1921,1270,625,550,281,367,2010,1967,233,328,1290,756,1489
0.32953079791525924,-0.18226795279044486,0.022527332531551376,-0.9404941645246845,0.41485233449395625,0.13372264733385414,-0.22862872657474756,0.9660662342487973,0.19959848010973788,-0.4173538681027949,-0.4895375675230639,-0.4653879408758077,1.7692815441810628,0.19959848010973788,-0.4173538681027949,0.32953079791525924,0.5200999892947062,0.1557501687575436,0.13372264733385414,1.553202877356439,1.2176973554481503,1.2746191459726386,0.06721945624007275,-0.6860379068899511,-0.2753114513174612,0.3723187418842105,1.804742035797999,3.1290816434117823,0.19959848010973788,-0.6116478542652064,-0.13622316069244658,2.8202460802749503,0.2648627970741298,-0.2519294648126461,-0.2519294648126461,-0.4173538681027949,0.39361707513132105,0.04490947737153897,-0.4653879408758077,-0.6363489276465712,-0.32232228259890044,0.04490947737153897,0.5200999892947062,0.6032126407743291,1.160355161006498,0.9266068390226809,-0.36966757047407667,-0.3459527147544944,1.3123375484934685,1.005321354697109,0.04490947737153897,0.41485233449395625,-0.06773581807620718
3,040
Degradation of beta catenin by the destruction complex
8
46
2.168612
0.030112
P49721,P28072,P49720,Q99436,P20618,P28070,P60900,P28074
Processes and pathways
Reactome Pathways
msigdb_reactome
32,260,133,367,138,177,50,242
839,1663,1293,2721,1094,991,2146,138,2068,844,621,1072,1106,177,260,242,936,565,1752,2468,1834,794,383,133,32,1410,1000,1598,1460,50,916,1798,1799,2081,771,1267,2156,1471,1921,894,1270,550,367,2010,756,1489
0.32953079791525924,-0.18226795279044486,0.022527332531551376,-0.9404941645246845,0.13372264733385414,0.19959848010973788,-0.4653879408758077,1.7692815441810628,-0.4173538681027949,0.32953079791525924,0.5200999892947062,0.1557501687575436,0.13372264733385414,1.553202877356439,1.2176973554481503,1.2746191459726386,0.24317501987691698,0.582523062344913,-0.22862872657474756,-0.6860379068899511,-0.2753114513174612,0.3723187418842105,0.8869402512163685,1.804742035797999,3.1290816434117823,-0.04505853001654639,0.19959848010973788,-0.13622316069244658,-0.06773581807620718,2.8202460802749503,0.2648627970741298,-0.2519294648126461,-0.2519294648126461,-0.4173538681027949,0.39361707513132105,0.04490947737153897,-0.4653879408758077,-0.06773581807620718,-0.32232228259890044,0.28648432191911377,0.04490947737153897,0.6032126407743291,0.9266068390226809,-0.36966757047407667,0.41485233449395625,-0.06773581807620718
3,040
Active transmembrane transporter activity
31
67
2.167414
0.030203
P13073,P16615,P98194,P41440,O43676,P31930,P61421,O43826,Q96ES6,P12235,Q03518,Q7KZN9,P03886,O00400,O96000,O75306,Q00325,P06576,Q9UDW1,Q02978,Q15388,P12236,P53985,P51798,O95168,Q9UBX3,Q9H936,Q9HD20,O75438,P28288,P08183
Functions
GO Molecular function
msigdb_gomf
762,764,800,146,269,647,152,151,157,789,425,178,47,53,311,57,696,694,71,583,463,580,95,477,473,232,637,118,240,622,255
53,1028,1132,269,151,1499,1450,57,240,785,473,1032,2550,311,1033,47,1169,1170,694,255,1793,2257,2919,789,580,762,764,1709,933,1174,993,2034,622,2911,647,1345,1590,146,1987,1596,477,847,2268,95,1380,152,800,696,583,425,463,1883,2657,1354,178,2424,2209,157,637,118,2217,906,232,71,2176,1630,2844
2.725483103215559,0.17770858414888777,0.11162542503352747,1.179516459667705,1.6978944756633867,-0.09048855958396525,-0.06773581807620718,2.67771886764343,1.2746191459726386,0.3723187418842105,0.7057948318332095,0.17770858414888777,-0.7613038169053663,1.0248732054561662,0.17770858414888777,2.929545586146746,0.0894578986082535,0.0894578986082535,0.4571356471709892,1.2367175827335657,-0.2519294648126461,-0.5381064762809528,-1.3708103994508807,0.3723187418842105,0.5617747326313666,0.39361707513132105,0.39361707513132105,-0.20540847316623317,0.24317501987691698,0.0894578986082535,0.19959848010973788,-0.3934676753169731,0.5200999892947062,-1.3429937902950162,0.4991726460209864,7.238315672777529e-05,-0.13622316069244658,1.715800083261279,-0.36966757047407667,-0.13622316069244658,0.7057948318332095,0.32953079791525924,-0.5381064762809528,2.185089936053244,-0.022456018591835984,1.6978944756633867,0.3723187418842105,0.4571356471709892,0.5617747326313666,0.7868475404440897,0.7261411670729521,-0.2987754614191971,-0.8374742177649565,7.238315672777529e-05,1.553202877356439,-0.6363489276465712,-0.4895375675230639,1.6619641606074178,0.5200999892947062,1.8927280853424016,-0.4895375675230639,0.28648432191911377,1.3123375484934685,2.5652503504888915,-0.4653879408758077,-0.13622316069244658,-1.1250106483577362
3,040
calmodulin-related
8
13
2.153307
0.031295
P41208,P0DP25,P80303,Q14257,Q8IYU8,Q9BPX6,Q15293,O43852
Functions
Panther Protein class
panther_protein_class
413,319,136,203,48,51,87,213
213,319,1307,738,413,941,136,1078,203,87,48,51,510
1.3685769357877944,1.005321354697109,0.022527332531551376,0.41485233449395625,0.8069734811215312,0.24317501987691698,1.7870310188063467,0.1557501687575436,1.4244174208729259,2.3358587073774046,2.867252154746337,2.8202460802749503,0.6649333439702259
3,040
Oxidoreductase complex
12
54
2.149716
0.031578
Q86Y39,Q9UDW1,P11177,P13674,Q96CU9,P03886,P31350,O43676,O75438,O75306,O43169,O14949
Localization
GO Cellular component
msigdb_gocc
164,71,9,202,108,47,272,269,240,57,29,190
2324,1028,190,29,269,1166,1450,57,240,785,473,2550,311,1134,911,47,1256,530,2553,2257,2724,2668,9,2579,202,2222,1640,1709,1551,360,2704,1304,2911,2647,272,647,2706,2767,532,1987,1714,847,1877,1997,2657,1354,164,108,1438,906,71,886,1732,2844
-0.5870410669585505,0.17770858414888777,1.4798666078148721,3.2046775288036393,1.179516459667705,0.0894578986082535,-0.06773581807620718,2.67771886764343,1.2746191459726386,0.3723187418842105,0.7057948318332095,-0.7613038169053663,1.0248732054561662,0.11162542503352747,0.2648627970741298,2.929545586146746,0.04490947737153897,0.6238439182752883,-0.7613038169053663,-0.5381064762809528,-0.9404941645246845,-0.8630705208373466,4.0121342775707145,-0.7865919937038053,1.4244174208729259,-0.5137767760722269,-0.15920642504678456,-0.20540847316623317,-0.11331744141047409,0.9266068390226809,-0.9145793033142863,0.022527332531551376,-1.3429937902950162,-0.8374742177649565,1.179516459667705,0.4991726460209864,-0.9145793033142863,-0.9926509483185962,0.6238439182752883,-0.36966757047407667,-0.20540847316623317,0.32953079791525924,-0.2987754614191971,-0.36966757047407667,-0.8374742177649565,7.238315672777529e-05,1.6077673117097622,1.9797856725780703,-0.04505853001654639,0.28648432191911377,2.5652503504888915,0.30804014209060904,-0.20540847316623317,-1.1250106483577362
3,040
Primary active transmembrane transporter activity
13
47
2.149102
0.031626
P51798,Q03518,Q9UDW1,P03886,Q7KZN9,Q15388,O43676,Q9HD20,P61421,O96000,O75438,O75306,P08183
Functions
GO Molecular function
msigdb_gomf
477,425,71,47,178,463,269,118,152,311,240,57,255
1028,1132,269,1499,1450,57,240,785,473,2550,311,1033,47,1169,694,255,2257,2919,762,764,1709,933,1174,993,2034,622,2911,647,1345,1590,1987,477,847,152,800,425,463,2657,1354,178,118,2217,906,71,2176,1630,2844
0.17770858414888777,0.11162542503352747,1.179516459667705,-0.09048855958396525,-0.06773581807620718,2.67771886764343,1.2746191459726386,0.3723187418842105,0.7057948318332095,-0.7613038169053663,1.0248732054561662,0.17770858414888777,2.929545586146746,0.0894578986082535,0.4571356471709892,1.2367175827335657,-0.5381064762809528,-1.3708103994508807,0.39361707513132105,0.39361707513132105,-0.20540847316623317,0.24317501987691698,0.0894578986082535,0.19959848010973788,-0.3934676753169731,0.5200999892947062,-1.3429937902950162,0.4991726460209864,7.238315672777529e-05,-0.13622316069244658,-0.36966757047407667,0.7057948318332095,0.32953079791525924,1.6978944756633867,0.3723187418842105,0.7868475404440897,0.7261411670729521,-0.8374742177649565,7.238315672777529e-05,1.553202877356439,1.8927280853424016,-0.4895375675230639,0.28648432191911377,2.5652503504888915,-0.4653879408758077,-0.13622316069244658,-1.1250106483577362
3,040
Organic acid transmembrane transport
15
28
2.131951
0.033011
Q9UJS0,O60831,Q9H2D1,P08183,O95563,O43772,Q9UBX3,P23786,Q8TDW0,P31751,Q02978,Q9H936,P41440,Q9Y619,P53985
Processes and pathways
GO Biological process
msigdb_gobp
557,504,66,255,167,40,232,106,236,520,583,637,146,185,95
40,504,1096,1500,167,1826,255,1793,912,106,622,520,1075,146,1039,2268,95,583,853,1883,2424,236,66,637,1157,232,557,185
2.9914106766594255,0.6649333439702259,0.13372264733385414,-0.09048855958396525,1.5896203443681522,-0.2753114513174612,1.2367175827335657,-0.2519294648126461,0.2648627970741298,2.014354642413987,0.5200999892947062,0.6444173395953164,0.1557501687575436,1.715800083261279,0.17770858414888777,-0.5381064762809528,2.185089936053244,0.5617747326313666,0.32953079791525924,-0.2987754614191971,-0.6363489276465712,1.2935010918758008,2.5975316656659477,0.5200999892947062,0.11162542503352747,1.3123375484934685,0.6032126407743291,1.5166189935414305
3,040
Organophosphate ester transport
10
28
2.116672
0.034288
Q9H2D1,Q14108,Q9BSK2,Q8TDW0,P41440,O00400,Q8WTV0,O43826,Q99808,P08183
Processes and pathways
GO Biological process
msigdb_gobp
66,301,77,236,146,53,22,151,90,255
53,461,151,1170,255,789,580,1828,1671,146,1457,2339,314,1384,301,972,2787,702,629,236,22,808,90,77,2317,66,1582,2245
2.725483103215559,0.7261411670729521,1.6978944756633867,0.0894578986082535,1.2367175827335657,0.3723187418842105,0.5617747326313666,-0.2753114513174612,-0.18226795279044486,1.715800083261279,-0.06773581807620718,-0.5870410669585505,1.0248732054561662,-0.022456018591835984,1.063827239756187,0.22142043515709942,-1.0188953886833905,0.4571356471709892,0.5200999892947062,1.2935010918758008,3.4278200746104854,0.3723187418842105,2.269179628829763,2.4676830441944553,-0.5625275930863287,2.5975316656659477,-0.11331744141047409,-0.5137767760722269
3,040
Regulation of hormone levels
20
61
2.106626
0.03515
Q14849,Q9HBH5,Q6NUM9,O43768,Q16836,O95563,P16435,O60678,P09455,O75844,P40939,O94788,Q8N5M9,P53985,Q06520,Q53GQ0,Q9HB40,Q9Y394,Q7Z7E8,O95470
Processes and pathways
GO Biological process
msigdb_gobp
131,285,414,411,39,167,423,431,195,69,212,214,221,95,98,354,103,371,363,380
838,930,2324,411,1586,431,69,214,380,167,1501,787,1169,2255,195,1036,1668,423,1708,2190,1828,1307,212,1263,1713,1039,2195,2228,95,2982,2708,2507,98,917,2530,1515,131,2423,522,39,354,414,627,363,1049,221,454,827,2209,1575,611,2426,2894,3031,978,103,285,908,1816,1730,371
0.32953079791525924,0.24317501987691698,-0.5870410669585505,0.8069734811215312,-0.13622316069244658,0.7666671108145032,2.5652503504888915,1.3685769357877944,0.8869402512163685,1.5896203443681522,-0.09048855958396525,0.3723187418842105,0.0894578986082535,-0.5381064762809528,1.4614265634176216,0.17770858414888777,-0.18226795279044486,0.7868475404440897,-0.20540847316623317,-0.4895375675230639,-0.2753114513174612,0.022527332531551376,1.3872343728517897,0.04490947737153897,-0.20540847316623317,0.17770858414888777,-0.4895375675230639,-0.5137767760722269,2.185089936053244,-1.6565192297626519,-0.9145793033142863,-0.7110278429358069,2.134232406148761,0.2648627970741298,-0.7361161262584145,-0.09048855958396525,1.8400495980357443,-0.6363489276465712,0.6444173395953164,3.006810954254387,0.9463622517624058,0.8069734811215312,0.5200999892947062,0.9266068390226809,0.17770858414888777,1.3498751782655338,0.7464317890494901,0.3509568225038281,-0.4895375675230639,-0.11331744141047409,0.5409671955712879,-0.6363489276465712,-1.2603180196379737,-2.508719155821819,0.22142043515709942,2.100156093249775,1.1218892605613975,0.28648432191911377,-0.2519294648126461,-0.20540847316623317,0.9266068390226809
3,040
Dehydrogenase
11
56
2.0989
0.035826
Q8N4Q0,Q8NCN5,Q8N8N7,Q96CU9,P03886,P49419,Q14914,P05091,O75438,O75306,O94788
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
1,257,105,108,47,16,246,270,240,57,214
1208,1166,1450,57,240,214,381,1134,1501,1740,47,2602,270,1256,2496,2724,1035,2259,2188,1551,2704,2911,2872,646,2647,1711,2525,2526,532,1713,16,1714,1595,847,2471,1310,1180,436,1953,1648,246,1354,2233,1143,1,105,257,1575,108,3031,498,1021,285,555,906,2516
0.06721945624007275,0.0894578986082535,-0.06773581807620718,2.67771886764343,1.2746191459726386,1.3685769357877944,0.8869402512163685,0.11162542503352747,-0.09048855958396525,-0.22862872657474756,2.929545586146746,-0.8119817547252068,1.179516459667705,0.04490947737153897,-0.7110278429358069,-0.9404941645246845,0.17770858414888777,-0.5381064762809528,-0.4895375675230639,-0.11331744141047409,-0.9145793033142863,-1.3429937902950162,-1.2058298802981928,0.4991726460209864,-0.8374742177649565,-0.20540847316623317,-0.7361161262584145,-0.7361161262584145,0.6238439182752883,-0.20540847316623317,3.631389293268725,-0.20540847316623317,-0.13622316069244658,0.32953079791525924,-0.6860379068899511,0.022527332531551376,0.0894578986082535,0.7666671108145032,-0.3459527147544944,-0.15920642504678456,1.2746191459726386,7.238315672777529e-05,-0.5137767760722269,0.11162542503352747,5.981212405325915,2.0487808812886414,1.2367175827335657,-0.11331744141047409,1.9797856725780703,-2.508719155821819,0.6853923652184316,0.19959848010973788,1.1218892605613975,0.6032126407743291,0.28648432191911377,-0.7110278429358069
3,040
Peptidase activity
42
111
2.084338
0.037129
O43464,P49720,P55786,P28072,Q16740,P09960,P20618,Q9UJ14,Q9BXS4,Q9NUQ7,O95630,Q0VDG4,Q9HBH5,O43847,P49721,P67812,P36551,Q96K76,P28070,P60900,Q99797,Q8TCT8,Q4J6C6,O75844,Q10713,Q9BYT8,Q8TCT9,P48147,Q9HB40,Q99436,P53582,Q9UIQ6,Q96FW1,Q5JRX3,P52888,Q9NZ08,P22695,P28074,Q9BT78,Q92905,Q96E52,Q92643
Functions
GO Molecular function
msigdb_gomf
503,133,6,260,523,259,138,393,275,408,26,27,285,159,32,163,288,37,177,50,54,194,322,69,215,487,347,220,103,367,107,501,366,362,361,119,360,242,377,376,124,508
1367,1293,2107,784,1701,503,159,1299,69,2948,1906,560,26,2925,2065,259,1101,2032,2367,1036,1708,1214,138,360,1072,177,260,242,2673,889,2746,288,1589,2469,1263,1645,220,133,32,2470,1000,1797,361,939,107,2944,2614,6,50,795,163,3034,27,215,2381,1318,2861,1472,1042,523,322,1924,362,1114,1847,2088,748,774,1390,1477,194,347,1016,508,2314,807,376,1234,923,661,1811,124,366,1121,37,2536,2009,367,2894,1394,54,902,377,275,487,2242,1244,2397,542,103,285,1198,862,1726,408,1482,119,501,393,1365,1446
-0.022456018591835984,0.022527332531551376,-0.44132700120879625,0.3723187418842105,-0.20540847316623317,0.6649333439702259,1.6439389719907391,0.022527332531551376,2.5652503504888915,-1.483411892468181,-0.32232228259890044,0.582523062344913,3.294580100112679,-1.3987587837144049,-0.4173538681027949,1.2176973554481503,0.13372264733385414,-0.3934676753169731,-0.6116478542652064,0.17770858414888777,-0.20540847316623317,0.06721945624007275,1.7692815441810628,0.9266068390226809,0.1557501687575436,1.553202877356439,1.2176973554481503,1.2746191459726386,-0.8630705208373466,0.28648432191911377,-0.9665176304872712,1.1025840074529036,-0.13622316069244658,-0.6860379068899511,0.04490947737153897,-0.15920642504678456,1.3498751782655338,1.804742035797999,3.1290816434117823,-0.6860379068899511,0.19959848010973788,-0.2519294648126461,0.9266068390226809,0.24317501987691698,2.014354642413987,-1.4550577626394943,-0.8119817547252068,5.13606374568797,2.8202460802749503,0.3723187418842105,1.6077673117097622,-3.9180307769305425,3.2796569851624366,1.3685769357877944,-0.6116478542652064,0.022527332531551376,-1.1787698895200653,-0.06773581807620718,0.17770858414888777,0.6444173395953164,1.005321354697109,-0.32232228259890044,0.9266068390226809,0.13372264733385414,-0.2753114513174612,-0.4173538681027949,0.41485233449395625,0.39361707513132105,-0.022456018591835984,-0.06773581807620718,1.4798666078148721,0.9660662342487973,0.19959848010973788,0.6649333439702259,-0.5625275930863287,0.3723187418842105,0.9067996292104508,0.06721945624007275,0.2648627970741298,0.4991726460209864,-0.2519294648126461,1.8752060118084188,0.9266068390226809,0.13372264733385414,3.0528553449126603,-0.7361161262584145,-0.36966757047407667,0.9266068390226809,-1.2603180196379737,-0.022456018591835984,2.725483103215559,0.28648432191911377,0.9067996292104508,1.179516459667705,0.7057948318332095,-0.5137767760722269,0.06721945624007275,-0.6116478542652064,0.6238439182752883,2.100156093249775,1.1218892605613975,0.0894578986082535,0.32953079791525924,-0.20540847316623317,0.8270453312183077,-0.06773581807620718,1.8927280853424016,0.6853923652184316,0.867028329570998,7.238315672777529e-05,-0.04505853001654639
3,040
Neutral lipid metabolic process
6
13
2.059225
0.039473
Q96N66,Q8NCG7,Q9UBV2,Q8NCC3,Q8WTV0,Q9NUQ2
Processes and pathways
GO Biological process
msigdb_gobp
197,298,209,17,22,153
1075,1039,2507,483,304,17,298,22,1325,197,755,153,209
0.1557501687575436,0.17770858414888777,-0.7110278429358069,0.7057948318332095,1.063827239756187,3.6025751739028236,1.0832301121348886,3.4278200746104854,0.022527332531551376,1.4614265634176216,0.41485233449395625,1.6978944756633867,1.405847774017092
3,040
Heterogeneous
9
44
2.051508
0.040217
O75844,Q16836,P00846,Q9NR77,Q15555,P03886,P21964,Q9Y619,Q9BQE5
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
69,39,73,11,204,47,112,185,25
1336,1788,69,1825,1501,73,1098,2495,47,1168,2296,1373,761,447,2997,789,3001,112,2334,1752,2302,212,649,2981,477,2944,2152,2339,1840,1386,698,2046,204,2385,39,1045,391,3020,25,754,11,3021,1092,185
7.238315672777529e-05,-0.2519294648126461,2.5652503504888915,-0.2753114513174612,-0.09048855958396525,2.5328492892945635,0.13372264733385414,-0.7110278429358069,2.929545586146746,0.0894578986082535,-0.5625275930863287,-0.022456018591835984,0.39361707513132105,0.7464317890494901,-1.8049031189212927,0.3723187418842105,-1.8653737098684169,1.9450723504514158,-0.5870410669585505,-0.22862872657474756,-0.5625275930863287,1.3872343728517897,0.4991726460209864,-1.6565192297626519,0.7057948318332095,-1.4550577626394943,-0.4653879408758077,-0.5870410669585505,-0.2753114513174612,-0.022456018591835984,0.4571356471709892,-0.3934676753169731,1.4244174208729259,-0.6116478542652064,3.006810954254387,0.17770858414888777,0.867028329570998,-2.242819633481233,3.324354402709241,0.41485233449395625,3.9148541626840703,-2.242819633481233,0.1557501687575436,1.5166189935414305
3,040
C type lectin receptors clrs
9
49
2.049378
0.040425
P49721,P28072,P49720,Q99436,P20618,P28070,P60900,P28074,Q05655
Processes and pathways
Reactome Pathways
msigdb_reactome
32,260,133,367,138,177,50,242,314
839,1663,1293,2721,1068,373,1094,1297,991,2146,138,2068,844,621,1072,1106,177,260,242,2468,1834,794,965,133,32,1000,1598,50,2039,2076,916,1798,1799,2081,771,314,1267,917,2342,2156,1921,1270,2126,948,550,367,2010,756,1489
0.32953079791525924,-0.18226795279044486,0.022527332531551376,-0.9404941645246845,0.1557501687575436,0.9067996292104508,0.13372264733385414,0.022527332531551376,0.19959848010973788,-0.4653879408758077,1.7692815441810628,-0.4173538681027949,0.32953079791525924,0.5200999892947062,0.1557501687575436,0.13372264733385414,1.553202877356439,1.2176973554481503,1.2746191459726386,-0.6860379068899511,-0.2753114513174612,0.3723187418842105,0.22142043515709942,1.804742035797999,3.1290816434117823,0.19959848010973788,-0.13622316069244658,2.8202460802749503,-0.3934676753169731,-0.4173538681027949,0.2648627970741298,-0.2519294648126461,-0.2519294648126461,-0.4173538681027949,0.39361707513132105,1.0248732054561662,0.04490947737153897,0.2648627970741298,-0.5870410669585505,-0.4653879408758077,-0.32232228259890044,0.04490947737153897,-0.44132700120879625,0.24317501987691698,0.6032126407743291,0.9266068390226809,-0.36966757047407667,0.41485233449395625,-0.06773581807620718
3,040
Target SNARE coiled-coil homology domain [IPR000727]
6
12
2.046575
0.0407
O43752,P56962,Q9UEU0,O15155,Q13190,O60499
Sequence
InterPro Domain
interpro_domain
132,320,201,141,142,239
838,141,1164,132,239,462,320,142,969,1012,201,1334
0.32953079791525924,1.7514933839084825,0.0894578986082535,1.804742035797999,1.2746191459726386,0.7261411670729521,1.005321354697109,1.7514933839084825,0.22142043515709942,0.19959848010973788,1.4429435920810105,0.022527332531551376
3,040
Phospholipid catabolic process
6
11
2.043814
0.040972
Q9NP80,Q8N2K0,Q8NCC3,Q8WTV0,Q9NXE4,Q05655
Processes and pathways
GO Biological process
msigdb_gobp
134,304,17,22,378,314
962,519,935,314,1047,304,17,1613,22,134,378
0.22142043515709942,0.6444173395953164,0.24317501987691698,1.0248732054561662,0.17770858414888777,1.063827239756187,3.6025751739028236,-0.13622316069244658,3.4278200746104854,1.804742035797999,0.9067996292104508
3,040
Active ion transmembrane transporter activity
7
39
2.039847
0.041366
Q9UDW1,P41440,O00400,P61421,Q9HD20,O43826,Q96ES6
Functions
GO Molecular function
msigdb_gomf
71,146,53,152,118,151,157
53,1132,151,1032,1033,1169,1170,694,1793,2257,2919,789,580,762,764,933,1174,993,2034,647,1345,1590,146,1596,477,2268,1380,152,800,696,583,178,2424,157,637,118,71,2176,1630
2.725483103215559,0.11162542503352747,1.6978944756633867,0.17770858414888777,0.17770858414888777,0.0894578986082535,0.0894578986082535,0.4571356471709892,-0.2519294648126461,-0.5381064762809528,-1.3708103994508807,0.3723187418842105,0.5617747326313666,0.39361707513132105,0.39361707513132105,0.24317501987691698,0.0894578986082535,0.19959848010973788,-0.3934676753169731,0.4991726460209864,7.238315672777529e-05,-0.13622316069244658,1.715800083261279,-0.13622316069244658,0.7057948318332095,-0.5381064762809528,-0.022456018591835984,1.6978944756633867,0.3723187418842105,0.4571356471709892,0.5617747326313666,1.553202877356439,-0.6363489276465712,1.6619641606074178,0.5200999892947062,1.8927280853424016,2.5652503504888915,-0.4653879408758077,-0.13622316069244658
3,040
Orc1 removal from chromatin
7
48
2.029997
0.042357
P49721,P49720,P20618,P28070,P60900,P28074,Q9Y619
Processes and pathways
Reactome Pathways
msigdb_reactome
32,133,138,177,50,242,185
839,1663,1293,2721,1094,991,2146,138,994,1710,2068,844,621,1072,1106,177,260,242,2301,1642,2035,2468,1834,794,133,32,2149,1000,1598,50,916,1798,1799,2081,771,1267,2156,2420,1921,1387,1270,550,367,2010,955,756,1489,185
0.32953079791525924,-0.18226795279044486,0.022527332531551376,-0.9404941645246845,0.13372264733385414,0.19959848010973788,-0.4653879408758077,1.7692815441810628,0.19959848010973788,-0.20540847316623317,-0.4173538681027949,0.32953079791525924,0.5200999892947062,0.1557501687575436,0.13372264733385414,1.553202877356439,1.2176973554481503,1.2746191459726386,-0.5625275930863287,-0.15920642504678456,-0.3934676753169731,-0.6860379068899511,-0.2753114513174612,0.3723187418842105,1.804742035797999,3.1290816434117823,-0.4653879408758077,0.19959848010973788,-0.13622316069244658,2.8202460802749503,0.2648627970741298,-0.2519294648126461,-0.2519294648126461,-0.4173538681027949,0.39361707513132105,0.04490947737153897,-0.4653879408758077,-0.6363489276465712,-0.32232228259890044,-0.022456018591835984,0.04490947737153897,0.6032126407743291,0.9266068390226809,-0.36966757047407667,0.24317501987691698,0.41485233449395625,-0.06773581807620718,1.5166189935414305
3,040
Congenital disorder of glycosylation
6
17
2.025158
0.042851
Q9BT22,Q8N511,P34949,P46977,Q9BV10,Q9HC07
Drugs and Diseases
Protein Atlas Disease involvement
protein_atlas_disease_involvement
293,148,115,279,59,156
1634,643,1672,115,2037,1219,279,999,1513,1353,148,879,293,59,1154,349,156
-0.15920642504678456,0.4991726460209864,-0.18226795279044486,1.8927280853424016,-0.3934676753169731,0.06721945624007275,1.160355161006498,0.19959848010973788,-0.09048855958396525,7.238315672777529e-05,1.715800083261279,0.30804014209060904,1.1025840074529036,2.67771886764343,0.11162542503352747,0.9660662342487973,1.679949247910155
3,040
Apical plasma membrane
9
39
2.018349
0.043555
P36551,P08183,O15020,P41440,Q99797,P61421,Q99808,Q86UE4,P53985
Localization
GO Cellular component
msigdb_gocc
288,255,317,146,54,152,90,355,95
2105,930,317,1297,1300,787,1169,255,1793,2255,2256,912,2298,1909,1104,933,993,1306,1553,1345,288,1590,146,1596,95,1179,1380,152,969,2620,427,355,2591,54,90,1583,2284,1288,2518
-0.44132700120879625,0.24317501987691698,1.005321354697109,0.022527332531551376,0.022527332531551376,0.3723187418842105,0.0894578986082535,1.2367175827335657,-0.2519294648126461,-0.5381064762809528,-0.5381064762809528,0.2648627970741298,-0.5625275930863287,-0.32232228259890044,0.13372264733385414,0.24317501987691698,0.19959848010973788,0.022527332531551376,-0.11331744141047409,7.238315672777529e-05,1.1025840074529036,-0.13622316069244658,1.715800083261279,-0.13622316069244658,2.185089936053244,0.0894578986082535,-0.022456018591835984,1.6978944756633867,0.22142043515709942,-0.8119817547252068,0.7868475404440897,0.9463622517624058,-0.7865919937038053,2.725483103215559,2.269179628829763,-0.11331744141047409,-0.5381064762809528,0.04490947737153897,-0.7110278429358069
3,040
Organic anion transmembrane transporter activity
14
27
2.017936
0.043598
Q9UJS0,Q9H2D1,O95563,Q9UBX3,Q02978,Q9H936,P41440,P12236,O43808,O00400,Q14728,Q9Y619,Q99808,P53985
Functions
GO Molecular function
msigdb_gomf
557,66,167,232,583,637,146,580,461,53,245,185,90,95
53,461,1096,167,1170,1793,912,789,580,146,2268,95,583,245,1883,972,2001,2424,629,90,66,637,1157,1582,232,557,185
2.725483103215559,0.7261411670729521,0.13372264733385414,1.5896203443681522,0.0894578986082535,-0.2519294648126461,0.2648627970741298,0.3723187418842105,0.5617747326313666,1.715800083261279,-0.5381064762809528,2.185089936053244,0.5617747326313666,1.2746191459726386,-0.2987754614191971,0.22142043515709942,-0.36966757047407667,-0.6363489276465712,0.5200999892947062,2.269179628829763,2.5975316656659477,0.5200999892947062,0.11162542503352747,-0.11331744141047409,1.3123375484934685,0.6032126407743291,1.5166189935414305
3,040
Calcium ion transport
9
51
2.016715
0.043725
P62942,P0DP25,O75844,Q9H4I9,Q8IYU8,Q9BPX6,P21796,P78417,Q9HC07
Processes and pathways
GO Biological process
msigdb_gobp
130,319,69,200,48,51,211,122,156
489,688,2362,2026,1299,69,1097,1032,1742,2328,1743,1793,319,1746,1035,1213,764,2223,519,933,211,2263,1307,1752,1948,820,1413,850,798,130,122,800,2155,547,917,2961,1515,1385,1276,48,2209,808,611,51,200,156,370,1815,2248,1585,1365
0.6853923652184316,0.4571356471709892,-0.6116478542652064,-0.3934676753169731,0.022527332531551376,2.5652503504888915,0.13372264733385414,0.17770858414888777,-0.22862872657474756,-0.5870410669585505,-0.22862872657474756,-0.2519294648126461,1.005321354697109,-0.22862872657474756,0.17770858414888777,0.06721945624007275,0.39361707513132105,-0.5137767760722269,0.6444173395953164,0.24317501987691698,1.3872343728517897,-0.5381064762809528,0.022527332531551376,-0.22862872657474756,-0.3459527147544944,0.3509568225038281,-0.04505853001654639,0.32953079791525924,0.3723187418842105,1.8400495980357443,1.8752060118084188,0.3723187418842105,-0.4653879408758077,0.6032126407743291,0.2648627970741298,-1.511904869971841,-0.09048855958396525,-0.022456018591835984,0.04490947737153897,2.867252154746337,-0.4895375675230639,0.3723187418842105,0.5409671955712879,2.8202460802749503,1.4429435920810105,1.679949247910155,0.9266068390226809,-0.2519294648126461,-0.5137767760722269,-0.11331744141047409,7.238315672777529e-05
3,040
Cytochrome complex assembly
10
14
1.992414
0.046326
Q9BSH4,Q15070,Q8N8Q8,Q9BSK2,Q7KZN9,Q9Y2R0,Q69YU5,Q96I36,Q6DKK2,O75880
Processes and pathways
GO Biological process
msigdb_gobp
325,196,264,77,178,86,216,316,482,559
1209,559,650,196,216,482,178,264,316,978,325,77,886,86
0.06721945624007275,0.582523062344913,0.4991726460209864,1.4614265634176216,1.3685769357877944,0.7057948318332095,1.553202877356439,1.1986304188795078,1.0248732054561662,0.22142043515709942,1.005321354697109,2.4676830441944553,0.30804014209060904,2.352447611616457
3,040
Mitochondrial substrate/solute carrier [IPR018108]
12
20
1.991775
0.046396
Q9Y6C9,Q9UJS0,Q9H2D1,Q9UBX3,O43772,Q9BSK2,Q9NZJ7,Q02978,P12236,O43808,Q9Y619,Q70HW3
Sequence
InterPro Repeat
interpro_repeat
160,557,66,232,40,77,174,583,580,461,185,63
40,461,1096,1170,789,580,2268,696,583,972,63,77,66,637,1582,174,232,557,185,160
2.9914106766594255,0.7261411670729521,0.13372264733385414,0.0894578986082535,0.3723187418842105,0.5617747326313666,-0.5381064762809528,0.4571356471709892,0.5617747326313666,0.22142043515709942,2.62969443108639,2.4676830441944553,2.5975316656659477,0.5200999892947062,-0.11331744141047409,1.571432284289661,1.3123375484934685,0.6032126407743291,1.5166189935414305,1.6258734378927253
3,040
SLC25 family of mitochondrial transporters
12
20
1.991775
0.046396
Q9Y6C9,Q9UJS0,Q9H2D1,Q9UBX3,O43772,Q9BSK2,Q9NZJ7,Q02978,P12236,O43808,Q9Y619,Q70HW3
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
160,557,66,232,40,77,174,583,580,461,185,63
40,461,1096,1170,789,580,2268,696,583,972,63,77,66,637,1582,174,232,557,185,160
2.9914106766594255,0.7261411670729521,0.13372264733385414,0.0894578986082535,0.3723187418842105,0.5617747326313666,-0.5381064762809528,0.4571356471709892,0.5617747326313666,0.22142043515709942,2.62969443108639,2.4676830441944553,2.5975316656659477,0.5200999892947062,-0.11331744141047409,1.571432284289661,1.3123375484934685,0.6032126407743291,1.5166189935414305,1.6258734378927253
3,040
Mitochondrial carrier domain superfamily [IPR023395]
12
20
1.991775
0.046396
Q9Y6C9,Q9UJS0,Q9H2D1,Q9UBX3,O43772,Q9BSK2,Q9NZJ7,Q02978,P12236,O43808,Q9Y619,Q70HW3
Sequence
InterPro Superfamily
interpro_homologous_superfamily
160,557,66,232,40,77,174,583,580,461,185,63
40,461,1096,1170,789,580,2268,696,583,972,63,77,66,637,1582,174,232,557,185,160
2.9914106766594255,0.7261411670729521,0.13372264733385414,0.0894578986082535,0.3723187418842105,0.5617747326313666,-0.5381064762809528,0.4571356471709892,0.5617747326313666,0.22142043515709942,2.62969443108639,2.4676830441944553,2.5975316656659477,0.5200999892947062,-0.11331744141047409,1.571432284289661,1.3123375484934685,0.6032126407743291,1.5166189935414305,1.6258734378927253
3,040
Fceri mediated nf kb activation
8
43
1.988834
0.04672
P49721,P28072,P49720,Q99436,P20618,P28070,P60900,P28074
Processes and pathways
Reactome Pathways
msigdb_reactome
32,260,133,367,138,177,50,242
839,1663,1293,2721,1068,373,1094,991,2146,138,2068,844,621,1072,1106,177,260,242,2468,1834,794,965,133,32,1000,1598,50,2076,916,1798,1799,2081,771,1267,2156,1921,1270,2126,550,367,2010,756,1489
0.32953079791525924,-0.18226795279044486,0.022527332531551376,-0.9404941645246845,0.1557501687575436,0.9067996292104508,0.13372264733385414,0.19959848010973788,-0.4653879408758077,1.7692815441810628,-0.4173538681027949,0.32953079791525924,0.5200999892947062,0.1557501687575436,0.13372264733385414,1.553202877356439,1.2176973554481503,1.2746191459726386,-0.6860379068899511,-0.2753114513174612,0.3723187418842105,0.22142043515709942,1.804742035797999,3.1290816434117823,0.19959848010973788,-0.13622316069244658,2.8202460802749503,-0.4173538681027949,0.2648627970741298,-0.2519294648126461,-0.2519294648126461,-0.4173538681027949,0.39361707513132105,0.04490947737153897,-0.4653879408758077,-0.32232228259890044,0.04490947737153897,-0.44132700120879625,0.6032126407743291,0.9266068390226809,-0.36966757047407667,0.41485233449395625,-0.06773581807620718
3,040
Proteasome complex
8
44
1.988786
0.046725
P49721,P28072,P49720,P20618,P28070,P60900,O43396,P28074
Localization
GO Cellular component
msigdb_gocc
32,260,133,138,177,50,277,242
839,1663,1293,2721,1094,277,991,2296,2146,138,2068,844,621,1072,1106,177,260,242,2468,1834,794,133,32,1000,2614,1876,1598,2197,50,916,1798,1799,2081,1267,2156,1270,2479,1082,550,367,2010,756,1489,1446
0.32953079791525924,-0.18226795279044486,0.022527332531551376,-0.9404941645246845,0.13372264733385414,1.160355161006498,0.19959848010973788,-0.5625275930863287,-0.4653879408758077,1.7692815441810628,-0.4173538681027949,0.32953079791525924,0.5200999892947062,0.1557501687575436,0.13372264733385414,1.553202877356439,1.2176973554481503,1.2746191459726386,-0.6860379068899511,-0.2753114513174612,0.3723187418842105,1.804742035797999,3.1290816434117823,0.19959848010973788,-0.8119817547252068,-0.2987754614191971,-0.13622316069244658,-0.4895375675230639,2.8202460802749503,0.2648627970741298,-0.2519294648126461,-0.2519294648126461,-0.4173538681027949,0.04490947737153897,-0.4653879408758077,0.04490947737153897,-0.6860379068899511,0.1557501687575436,0.6032126407743291,0.9266068390226809,-0.36966757047407667,0.41485233449395625,-0.06773581807620718,-0.04505853001654639
3,040
Fad binding
6
9
1.985047
0.047139
Q8NB78,Q15067,Q15392,Q14534,O15254,O95831
Functions
GO Molecular function
msigdb_gomf
292,521,143,495,120,381
1366,120,381,911,495,521,143,292,611
-0.022456018591835984,1.8752060118084188,0.8869402512163685,0.2648627970741298,0.6853923652184316,0.6444173395953164,1.7514933839084825,1.1025840074529036,0.5409671955712879
3,040
Acylglycerol o acyltransferase activity
6
9
1.979213
0.047792
Q96N66,Q8NCC3,Q7L5N7,Q9NUQ2,Q86UL3,Q6P1A2
Functions
GO Molecular function
msigdb_gomf
197,17,628,153,483,61
61,628,483,17,659,1325,197,1857,153
2.661739823625172,0.5200999892947062,0.7057948318332095,3.6025751739028236,0.4991726460209864,0.022527332531551376,1.4614265634176216,-0.2753114513174612,1.6978944756633867
3,040
Uch proteinases
8
42
1.972409
0.048563
P49721,Q8NB78,P28072,P49720,P20618,P28070,P60900,P28074
Processes and pathways
Reactome Pathways
msigdb_reactome
32,292,260,133,138,177,50,242
839,1663,1293,2721,1368,1094,991,1907,2146,138,2068,844,621,1072,1106,177,260,242,2468,1834,794,133,32,2891,1000,1598,50,916,1798,1799,2081,1267,2156,1270,292,550,367,2010,756,1489,1698,1446
0.32953079791525924,-0.18226795279044486,0.022527332531551376,-0.9404941645246845,-0.022456018591835984,0.13372264733385414,0.19959848010973788,-0.32232228259890044,-0.4653879408758077,1.7692815441810628,-0.4173538681027949,0.32953079791525924,0.5200999892947062,0.1557501687575436,0.13372264733385414,1.553202877356439,1.2176973554481503,1.2746191459726386,-0.6860379068899511,-0.2753114513174612,0.3723187418842105,1.804742035797999,3.1290816434117823,-1.2603180196379737,0.19959848010973788,-0.13622316069244658,2.8202460802749503,0.2648627970741298,-0.2519294648126461,-0.2519294648126461,-0.4173538681027949,0.04490947737153897,-0.4653879408758077,0.04490947737153897,1.1025840074529036,0.6032126407743291,0.9266068390226809,-0.36966757047407667,0.41485233449395625,-0.06773581807620718,-0.18226795279044486,-0.04505853001654639
3,040