term
stringlengths
2
121
overlap
int64
6
281
setsize
int64
7
499
score
float64
1.96
10.6
pval
float64
0
0.05
edge
stringlengths
41
1.97k
type
stringclasses
5 values
subtype
stringclasses
24 values
subtype_key
stringclasses
24 values
edge_idxs
stringlengths
11
1.17k
ann_idxs
stringlengths
19
2.31k
ann_vals
stringlengths
124
9.94k
sig_size
int64
2.2k
3.73k
Regulation of oxidoreductase activity
6
15
2.608464
0.009095
P0DP25,P16435,P00374,Q8TCT9,Q8WTV0,Q15070
Processes and pathways
GO Biological process
msigdb_gobp
72,175,216,124,221,60
964,216,1221,292,1579,72,175,60,124,221,2981,646,1377,1595,2865
0.25396851053519315,1.573316957055108,0.030736330125996712,1.3468887104804244,-0.22811391955386917,2.3921809662769813,1.7512674340218852,2.495021804682221,2.0445744152136456,1.5627036240741825,-1.5677651074261831,0.6303713421013281,-0.07700433730373651,-0.22811391955386917,-1.1370667422921092
3,040
Other glycan degradation
6
8
2.390726
0.016815
P07686,P06865,Q9BTY2,P16278,P04066,O00462
Processes and pathways
KEGG Pathways
msigdb_kegg
98,8,53,55,26,61
61,140,762,26,8,98,55,53
2.3434927365373808,1.3370471534985773,0.3616471354352151,3.6331913800857625,4.522011041983279,1.7017187419643311,2.4219359742936546,2.461207064533273
3,016
Dysostosis multiplex
6
8
2.160199
0.030757
P08236,O00754,P54802,P15586,P16278,P04066
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
164,140,76,49,55,26
140,26,164,254,49,55,76,515
1.3370471534985773,3.6331913800857625,1.1657035019459028,0.8447751205900944,2.539846619734708,2.4219359742936546,2.031088212195708,0.5463450339601905
3,016
Peptidase activity
35
111
2.149455
0.031598
Q4J6C6,P09960,Q9NUQ7,Q92905,P28070,Q9BYT8,P25789,Q10713,P67812,Q9BXS4,Q96E52,P55786,Q9Y5K5,O43847,Q86UV5,Q16740,Q6P2Q9,Q9HBH5,P49721,P49720,P28074,Q96FW1,Q969V3,Q14694,P61009,O94966,Q5JRX3,Q96FZ2,Q9NZ08,Q9UJ14,Q99797,Q0VDG4,P22695,Q9UIQ6,P20618
Functions
GO Molecular function
msigdb_gomf
383,6,411,408,19,281,397,403,158,31,296,45,316,50,450,311,178,68,69,195,330,484,86,475,227,94,98,369,240,372,111,234,361,118,120
602,2439,1692,1549,2207,2371,50,702,666,2746,1555,94,2599,2957,1559,6,2403,2667,1311,979,2168,2056,120,361,397,19,906,330,2704,521,2829,1650,2015,2058,2449,1234,1062,195,69,1410,2175,842,1318,1066,2344,2919,1617,45,768,227,158,1820,234,403,1877,1518,2785,475,773,311,383,950,98,1245,178,2028,678,719,450,2385,1478,685,1480,557,2684,723,408,959,483,86,2361,296,484,369,2195,2754,2881,1333,2616,2428,111,2948,1252,31,281,3029,826,1437,1122,657,68,2472,1336,2364,411,1680,240,118,372,2331,316
0.6202104499779444,-0.6539941020236397,-0.14377165561391486,-0.05597625065569513,-0.4715028974630592,-0.592878082828186,2.3199431271301907,0.5383503282042649,0.5657253485481226,-1.0265298635508193,-0.05597625065569513,1.7622359921018145,-0.8080131796942459,-1.6686393186260444,-0.05597625065569513,4.399838655596055,-0.623400661621177,-0.9012550743025559,0.08878972289063765,0.3162419588863489,-0.4413395452957021,-0.3512880145259206,1.544997744895441,0.8872872953578977,0.8345706454824449,3.4630508760503385,0.37227980553063694,0.9396713728014896,-0.9324723217073413,0.7012672235238908,-1.216445898202047,-0.11442948013265918,-0.32141818105389924,-0.3512880145259206,-0.6539941020236397,0.14614048457140377,0.25987026196309276,1.2474250072171498,2.021519248294384,0.031119757815354213,-0.4413395452957021,0.42797987013247024,0.08878972289063765,0.25987026196309276,-0.5624266885187066,-1.5057145188825194,-0.08516421284467109,2.4549918940111244,0.4833381025022259,1.171494698519176,1.3974017862744008,-0.20268516882665863,1.146039821857207,0.8345706454824449,-0.2322557377329396,-0.026865995657129237,-1.0895702346244323,0.7548533811904994,0.4833381025022259,0.9917310216397119,0.8609710649137305,0.3443028565185778,1.7383335266591304,0.14614048457140377,1.2976912739842386,-0.32141818105389924,0.5657253485481226,0.5383503282042649,0.7815129153563914,-0.592878082828186,0.002166144764581763,0.5657253485481226,0.002166144764581763,0.6743385231662086,-0.9012550743025559,0.5383503282042649,0.8345706454824449,0.3443028565185778,0.7548533811904994,1.8336039789827883,-0.5624266885187066,1.0176416361565288,0.7548533811904994,0.8872872953578977,-0.4413395452957021,-1.0265298635508193,-1.3443672675429474,0.08878972289063765,-0.8080131796942459,-0.623400661621177,1.617948117927611,-1.6032819984989526,0.14614048457140377,2.894090143639614,1.04347404354027,-3.629198296361711,0.4557019732657103,0.031119757815354213,0.23156041728940535,0.5930122423361401,2.0679736357625047,-0.6539941020236397,0.08878972289063765,-0.5624266885187066,0.8345706454824449,-0.11442948013265918,1.146039821857207,1.569375848756772,0.8872872953578977,-0.532046805287746,0.9917310216397119
3,039
Transporter activity
50
165
2.144459
0.031996
P28288,Q9UNF0,Q93050,Q00325,P51991,P61619,Q96SU4,O43772,Q96ES6,Q6N075,Q99808,P41440,P38435,Q9BSK2,O15173,Q9HD20,Q9UBX3,Q9H2D1,Q70HW3,O14925,O75027,Q6P4A7,Q8TDW0,Q96GC9,P03886,Q9HC07,Q7L0J3,O75251,Q14728,O00400,Q9UDW1,Q9Y487,Q9H0U3,Q99567,Q9Y619,Q99595,Q14849,O60830,Q9NS69,P49821,P12235,Q9Y584,Q7KZN9,P51798,O75438,Q99797,Q9Y277,Q03518,O43676,P56134
Functions
GO Molecular function
msigdb_gomf
251,532,139,253,376,379,10,12,13,267,152,23,399,26,29,299,432,39,42,415,49,422,51,182,303,63,449,317,198,75,76,84,353,486,93,96,228,101,102,470,490,109,105,104,358,111,511,121,119,497
601,2048,75,1546,2625,415,2827,29,119,1550,12,1641,516,101,49,317,701,358,2336,977,2482,1900,802,1178,734,1500,2399,1702,1092,2164,1353,303,1952,1502,1180,1953,2570,1181,3012,1955,2864,1184,2970,1452,490,764,2572,1136,1454,1230,1854,2489,1609,1359,571,1855,2339,2797,251,2519,1363,1139,2410,399,1613,23,941,2578,1459,1511,470,1971,104,2580,376,1066,1019,1974,2546,497,2971,2607,379,1759,610,253,2106,2416,817,121,2313,1571,2928,198,2108,228,2972,2772,2421,2188,267,2988,716,2610,422,1158,42,105,449,616,2235,3026,2773,653,918,721,1076,745,1210,51,2356,139,13,182,1251,10,486,96,111,152,2948,26,3016,783,1835,692,353,852,39,2802,2291,1217,2390,63,725,299,2080,102,1999,828,432,76,1304,1943,1305,2330,532,511,84,109,2793,3027,93,1126,2991
0.6202104499779444,-0.3512880145259206,1.9279886550597911,-0.05597625065569513,-0.8390252094805041,0.8080849620418975,-1.216445898202047,2.958588233083501,1.544997744895441,-0.05597625065569513,3.9092343675765657,-0.11442948013265918,0.7012672235238908,1.690355657787928,2.3651402347579222,0.9657412554167276,0.5383503282042649,0.8872872953578977,-0.5624266885187066,0.3162419588863489,-0.6846580848150519,-0.26190167698392064,0.4557019732657103,0.17469507127831135,0.5108877321095047,-0.026865995657129237,-0.623400661621177,-0.14377165561391486,0.23156041728940535,-0.4413395452957021,0.059994425177554336,0.9917310216397119,-0.29162261406547985,-0.026865995657129237,0.17469507127831135,-0.29162261406547985,-0.7770701487504792,0.17469507127831135,-2.5401967106836616,-0.29162261406547985,-1.312289800490795,0.17469507127831135,-1.7671391794902984,0.002166144764581763,0.7281052094893912,0.4833381025022259,-0.7770701487504792,0.20316853354952225,0.002166144764581763,0.14614048457140377,-0.2322557377329396,-0.6846580848150519,-0.08516421284467109,0.059994425177554336,0.6473194028710747,-0.2322557377329396,-0.5624266885187066,-1.1211901915515736,1.0949079181735943,-0.7153922943626307,0.059994425177554336,0.20316853354952225,-0.623400661621177,0.8345706454824449,-0.08516421284467109,3.2132963315742646,0.3443028565185778,-0.7770701487504792,0.002166144764581763,-0.026865995657129237,0.7548533811904994,-0.29162261406547985,1.6421434911614463,-0.7770701487504792,0.8609710649137305,0.25987026196309276,0.28809760044894905,-0.29162261406547985,-0.7461964185571768,0.7281052094893912,-1.7671391794902984,-0.8080131796942459,0.8609710649137305,-0.17319034746204157,0.6202104499779444,1.0949079181735943,-0.3812317554711987,-0.623400661621177,0.4557019732657103,1.544997744895441,-0.532046805287746,-0.05597625065569513,-1.5381742322746308,1.2474250072171498,-0.3812317554711987,1.171494698519176,-1.7671391794902984,-1.0580167005225047,-0.623400661621177,-0.4413395452957021,1.0692291688444036,-1.9657867286587134,0.5383503282042649,-0.8080131796942459,0.8080849620418975,0.20316853354952225,2.4996520829893805,1.6421434911614463,0.7815129153563914,0.6202104499779444,-0.4715028974630592,-3.2722712318105267,-1.0580167005225047,0.5930122423361401,0.37227980553063694,0.5383503282042649,0.25987026196309276,0.5108877321095047,0.17469507127831135,2.3199431271301907,-0.5624266885187066,1.471488083365916,3.8892609623096273,1.2976912739842386,0.14614048457140377,3.968986965823307,0.7548533811904994,1.7622359921018145,1.617948117927611,1.422162398843442,-1.6032819984989526,2.980012792431638,-2.608867981186923,0.4833381025022259,-0.20268516882665863,0.5657253485481226,0.9135203883778802,0.42797987013247024,2.544138810151577,-1.1211901915515736,-0.5017387635204503,0.17469507127831135,-0.592878082828186,2.183231172677363,0.5383503282042649,1.0176416361565288,-0.3512880145259206,1.690355657787928,-0.29162261406547985,0.4557019732657103,0.8080849620418975,1.9279886550597911,0.11750522122821545,-0.26190167698392064,0.11750522122821545,-0.532046805287746,0.7012672235238908,0.7281052094893912,1.8572819168716963,1.6421434911614463,-1.0895702346244323,-3.2722712318105267,1.7860815359443791,0.23156041728940535,-1.9657867286587134
3,039
Threonine type peptidase activity
6
10
2.106789
0.035136
P49721,P49720,Q9UJ14,P28074,P28070,P20618
Functions
GO Molecular function
msigdb_gomf
69,195,372,330,19,120
120,397,19,906,330,195,69,2028,1333,372
1.544997744895441,0.8345706454824449,3.4630508760503385,0.37227980553063694,0.9396713728014896,1.2474250072171498,2.021519248294384,-0.32141818105389924,0.08878972289063765,0.8872872953578977
3,039
Abnormal b cell morphology
6
10
2.034101
0.041941
P42224,Q9BV10,P17812,P00813,O60934,Q05655
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
343,298,360,359,126,159
435,126,1748,359,360,343,1614,1970,159,298
0.7815129153563914,1.4960544987548756,-0.17319034746204157,0.8872872953578977,0.8872872953578977,0.9135203883778802,-0.08516421284467109,-0.29162261406547985,1.3974017862744008,1.0176416361565288
3,039
Intrinsic component of organelle membrane
90
139
5.071545
0
Q15125,O60830,Q99595,Q5T9L3,Q86YN1,Q9H4I9,Q9Y2R0,Q9GZY8,Q53H12,Q13505,Q8TCT9,P57105,Q9HC21,Q9HCU5,O43752,Q9Y282,P10321,Q8N697,Q9Y6N1,Q9NQC3,O75844,Q15629,O75880,O96008,Q9BTV4,Q96S52,Q9BUN8,Q9Y4P3,Q9BUR5,Q15070,Q9NX63,O95070,P42892,O95140,O00767,L0R6Q1,Q8N4V1,Q9BPX6,Q96A33,Q8TB61,Q6ZRP7,Q16891,O43292,O75431,Q9NVH1,Q9P035,O75192,Q8TCT8,O14925,Q5XKP0,Q9UG56,Q9H3K2,O15118,Q86XL3,Q8N8Q8,O95470,Q9BWH2,Q9NPA0,Q9Y5Y5,Q5H8A4,Q14739,Q6P4A7,O15155,O43826,Q99442,P12235,O43505,Q9Y5U9,P98194,Q7L0J3,Q92643,Q12981,O15258,Q15388,O43808,P51572,P57088,Q03518,Q5SNT2,Q9NRB3,Q15041,O43819,Q15006,Q9BUB7,P27824,P17152,O76024,Q86Y82,O94901,Q9Y512
Localization
GO Cellular component
msigdb_gocc
4,5,6,11,12,16,17,530,548,39,40,46,561,570,51,65,575,588,594,71,77,79,595,601,620,619,110,115,116,120,633,118,122,636,634,140,143,659,154,157,160,672,669,169,689,173,174,185,202,212,223,231,238,243,248,261,263,273,289,295,307,311,321,332,342,345,348,356,364,370,371,377,379,394,390,391,403,404,410,417,425,428,439,450,453,460,475,484,489,498
1473,140,634,202,238,763,321,379,669,2059,348,51,390,428,332,704,5,174,169,77,595,475,967,489,118,636,261,1046,601,905,813,575,345,460,935,1845,2485,453,2523,2435,122,2138,862,1153,391,403,46,1389,1020,364,849,404,1175,377,39,1725,307,439,425,120,4,394,79,974,1190,672,548,295,1036,410,11,212,311,1126,160,370,686,243,484,12,1007,841,1024,143,588,1160,248,2333,1358,757,157,185,40,1127,371,888,154,619,342,6,659,1879,620,450,110,116,263,530,231,1145,16,1548,1401,561,570,273,71,417,3017,689,633,1165,173,2449,1234,223,721,914,795,65,17,1714,115,1068,498,356,289,1345,594
-0.1333611726485954,1.964897593179475,0.6213449936127172,1.6372812858760162,1.4990510731461264,0.4702605562765458,1.2241190154546975,1.0414134334695793,0.57140782105902,-0.46771987659621755,1.1220252798248234,2.626663982355961,1.0181828688945016,0.9479503532206887,1.1902781082588905,0.5336786310815371,3.5833547818711566,1.7724755011768645,1.7930143140179442,2.370264417454816,0.6708680977120229,0.864965105135409,0.24942576442222106,0.8410433975918085,2.0932019556415513,0.6213449936127172,1.4124116297329234,0.18287360405382397,0.6585257316553426,0.3021326319906221,0.4190345519703002,0.6954766988270652,1.1448616242246488,0.8887920767692477,0.2758379519036087,-0.3492237281963389,-0.7279101605274243,0.9006702914867534,-0.7593104723132084,-0.6966810077118192,2.0834256614858373,-0.4977273208231059,0.3543739888991153,0.08841928230327178,1.0181828688945016,1.0065340223336994,2.6713750460920487,-0.07712328202431389,0.2095846341582732,1.0760928564449042,0.36736263752585335,1.0065340223336994,0.0748011186548802,1.0529953384136446,2.7598629433409028,-0.2763755385948963,1.2912412532455868,0.9243566825638713,0.9597126649630634,2.0932019556415513,3.6218978537046036,1.0181828688945016,2.360911550267849,0.24942576442222106,0.061151309647997754,0.57140782105902,0.7443925370224047,1.3134519523684933,0.19624424562674062,0.9948626739598494,3.3471659553996225,1.5950791374165418,1.2689492993639755,0.11556131040259485,1.8440649572883736,1.0645551154147626,0.5588579410317828,1.488287926722168,0.8530161446660425,3.3471659553996225,0.22289491850198123,0.3803228835675519,0.2095846341582732,1.954917564819329,0.6831850488258874,0.08841928230327178,1.477505845798672,-0.6193437716665054,-0.04920595720837689,0.48299836247200467,1.8643679316323016,1.7104461511591396,2.7598629433409028,0.11556131040259485,1.0645551154147626,0.3283109386072143,1.904775442700116,0.6461578360344038,1.1562476399214794,3.575618702542787,0.5964286373641703,-0.36390379043786164,0.6461578360344038,0.9125251267176329,2.1612105866232185,2.1127087039343455,1.4124116297329234,0.7687015520901122,1.5312276267961478,0.10200596012172755,3.2175824750230393,-0.1616845798336536,-0.07712328202431389,0.7199845468995671,0.7077431607617762,1.37960291235598,2.435348044661633,0.9831687287835464,-2.412780764474814,0.5588579410317828,0.6337642954290207,0.08841928230327178,1.782753437123811,-0.6966810077118192,0.033756111184921174,1.5632363492107093,0.5210489561099639,0.3021326319906221,0.44470276814533355,2.4814280266167166,3.176547547397983,-0.26191492372509495,2.1224392619869463,0.16947255944840645,0.8290467604251529,1.1105747746411097,1.3466170528239039,-0.03529708956303091,0.6831850488258874
3,040
Ion transmembrane transporter activity
48
96
4.7765
0.000002
Q9UDW1,P06576,Q9H2D1,O43808,Q8N4V1,Q93050,P16615,Q9HD20,P13073,Q8TB61,Q99808,Q8TDW0,P00846,Q9H936,Q9HC21,O95202,Q9Y619,Q70HW3,Q9C0H2,Q6P4A7,P05023,Q6PML9,P36543,P12236,P24539,Q8N697,Q9Y277,P56134,Q13423,Q9UJS0,O43826,Q6NUK1,P51790,P12235,Q14728,O75964,Q7KZN9,P21796,Q9HC07,Q9H0U3,Q9UBX3,O43681,Q9Y487,O00400,Q8NEW0,P98194,P53985,P45880
Functions
GO Molecular function
msigdb_gomf
2,387,8,390,143,146,274,150,398,157,286,550,34,296,561,50,52,53,54,311,563,312,564,314,322,588,199,454,204,464,332,82,596,345,218,90,222,96,97,487,104,612,105,109,492,364,628,123
2757,109,702,612,1504,390,332,880,1032,90,50,1046,731,34,563,653,387,1893,1844,732,1694,871,2034,750,345,314,398,274,935,861,1644,2433,96,322,1979,1225,1187,564,2434,1189,123,1320,596,754,895,628,896,454,1001,1411,1020,364,849,1302,736,204,218,1873,1542,3007,82,2443,311,312,53,222,143,588,1358,492,157,550,146,1053,641,286,1164,54,487,8,296,1548,97,561,150,820,104,2,1712,464,795,199,105,1292,52,1690
-1.0004827835760666,2.170865945299008,0.5336786310815371,0.6461578360344038,-0.14750568765470307,1.0181828688945016,1.1902781082588905,0.3283109386072143,0.19624424562674062,2.276103138392118,2.635631465461991,0.18287360405382397,0.49570894697737444,2.9075240878120137,0.7077431607617762,0.5964286373641703,1.0298093080175974,-0.3786211358393844,-0.3492237281963389,0.49570894697737444,-0.26191492372509495,0.3413568016183609,-0.45277442063761514,0.48299836247200467,1.1448616242246488,1.2577726487807976,1.0065340223336994,1.3686274111665022,0.2758379519036087,0.3543739888991153,-0.2331011456054219,-0.6966810077118192,2.247577005884701,1.2241190154546975,-0.4229989506921864,0.033756111184921174,0.061151309647997754,0.7077431607617762,-0.6966810077118192,0.061151309647997754,2.0834256614858373,-0.021421189614910855,0.6708680977120229,0.48299836247200467,0.31523626177182246,0.6337642954290207,0.31523626177182246,0.9006702914867534,0.22289491850198123,-0.09113208586471662,0.2095846341582732,1.0760928564449042,0.36736263752585335,-0.007578087459911156,0.49570894697737444,1.6372812858760162,1.5844831960754728,-0.36390379043786164,-0.1616845798336536,-1.9267497642243225,2.351544747161577,-0.6966810077118192,1.2689492993639755,1.2689492993639755,2.6086908370116504,1.5632363492107093,1.954917564819329,0.6831850488258874,-0.04920595720837689,0.8410433975918085,1.8643679316323016,0.7443925370224047,1.944921479987834,0.18287360405382397,0.6213449936127172,1.3466170528239039,0.08841928230327178,2.6086908370116504,0.8530161446660425,3.4977473541425774,1.3134519523684933,-0.1616845798336536,2.247577005884701,0.7199845468995671,1.9248809148764459,0.4190345519703002,2.199742892007449,3.7813362177920875,-0.26191492372509495,0.8887920767692477,0.44470276814533355,1.6582743358244223,2.199742892007449,0.006232385460175731,2.617683785993935,-0.24749019058283162
3,040
Mitochondrial transport
43
83
4.584795
0.000005
Q10713,P06576,O60830,Q99595,Q9Y371,Q9Y5J9,Q9NS69,Q15388,Q5JRX3,P51572,Q9GZY8,O95831,O43464,P62072,Q53H12,P00846,O95429,O75431,Q14849,Q8N4H5,Q9Y584,Q3ZCQ8,O14737,Q9P0J0,P23786,P24539,P56134,Q9UJS0,O14925,Q6NUK1,O43615,P12235,O75964,O00165,O96008,Q9UBX3,Q99797,O60220,Q9Y512,Q8N8Q8,Q15070,P55786,P45880
Processes and pathways
GO Biological process
msigdb_gobp
131,387,5,6,389,264,9,394,526,391,530,23,408,29,548,34,421,169,43,49,60,566,317,451,447,322,454,464,202,82,340,345,90,473,601,104,495,233,498,248,120,247,123
473,317,202,408,340,1504,233,5,1237,169,1297,1032,90,967,636,421,1776,23,601,34,1596,653,387,2576,1815,2805,345,1868,447,322,1979,2838,2926,2943,1187,2749,123,1320,817,1273,862,391,1101,247,454,1001,29,1676,131,43,120,394,2753,566,548,526,82,2121,841,1024,49,248,757,618,1686,6,495,530,1260,3017,9,451,2269,104,946,464,1221,1792,389,498,60,264,2909
0.864965105135409,1.2465754397744402,1.6372812858760162,0.9948626739598494,1.1562476399214794,-0.14750568765470307,1.509795357420363,3.5833547818711566,0.020010396372018485,1.7930143140179442,-0.007578087459911156,0.19624424562674062,2.276103138392118,0.24942576442222106,0.6213449936127172,0.9714520911959001,-0.30540519590093435,3.085338247748161,0.6585257316553426,2.9075240878120137,-0.20442935390032577,0.5964286373641703,1.0298093080175974,-0.8067363769252331,-0.33458074379489317,-1.0665598073816422,1.1448616242246488,-0.36390379043786164,0.9125251267176329,1.2241190154546975,-0.4229989506921864,-1.1334162316136511,-1.338869380346214,-1.3738525898967593,0.061151309647997754,-0.984083002121523,2.0834256614858373,-0.021421189614910855,0.4190345519703002,0.006232385460175731,0.3543739888991153,1.0181828688945016,0.1290854902149427,1.477505845798672,0.9006702914867534,0.22289491850198123,3.0266138343517364,-0.24749019058283162,2.0145588418698184,2.706918315651424,2.0932019556415513,1.0181828688945016,-0.984083002121523,0.7077431607617762,0.7443925370224047,0.7687015520901122,2.351544747161577,-0.4827041033346785,0.3803228835675519,0.2095846341582732,2.6445862744892894,1.477505845798672,0.48299836247200467,0.6461578360344038,-0.24749019058283162,3.575618702542787,0.8410433975918085,0.7687015520901122,0.020010396372018485,-2.412780764474814,3.4820604215174513,0.9125251267176329,-0.5734361048340421,2.199742892007449,0.2758379519036087,0.8887920767692477,0.047469694504802575,-0.30540519590093435,1.0298093080175974,0.8290467604251529,2.4997661556800703,1.4124116297329234,-1.269549423261982
3,040
er
43
95
4.402904
0.000011
Q96N66,Q15125,Q07065,O95470,Q969Q5,P51572,Q8N4V1,Q9NPA0,Q86Y07,Q15363,Q15392,Q96A33,Q9NTJ5,P49755,Q9NR31,Q15041,Q16850,Q96GC9,Q14739,Q7L5N7,Q15006,Q6NUK4,Q9P2W9,Q9NQC3,P27824,O00264,Q00765,Q9Y5M8,Q06136,P61026,O15173,Q13190,O96005,Q99640,Q12981,P46977,Q9Y487,O00400,Q8NHH9,Q9H6H4,O15121,O15269,Q8TBX8
Localization
OpenCell Localization
opencell_localization
129,4,132,261,262,391,143,273,405,19,152,154,541,547,416,425,170,175,307,567,439,324,69,71,453,201,336,80,461,469,81,217,92,354,377,227,105,109,244,256,505,245,126
201,109,634,574,505,81,245,903,2059,704,2181,1170,681,1619,261,951,92,952,933,692,1316,1798,2480,1532,2718,453,1960,227,956,1047,547,2877,1274,391,1753,1696,2109,724,469,2399,1563,336,461,132,2378,377,217,307,439,425,4,19,152,2819,1487,170,1036,922,324,2443,567,2467,740,405,143,1160,2333,805,244,126,742,1162,1659,262,1518,154,175,129,354,1879,1009,256,1129,273,71,416,541,1947,820,69,795,2248,105,80,728
1.6372812858760162,2.170865945299008,0.6213449936127172,0.6954766988270652,0.8049813983798076,2.351544747161577,1.477505845798672,0.3021326319906221,-0.46771987659621755,0.5336786310815371,-0.5278916176011564,0.0748011186548802,0.5588579410317828,-0.21874759683495115,1.4124116297329234,0.2626466181221558,2.266608843369935,0.2626466181221558,0.2758379519036087,0.5462815850690601,-0.021421189614910855,-0.31997463365124035,-0.7279101605274243,-0.1616845798336536,-0.9514247127867999,0.9006702914867534,-0.40816850621130574,1.541915754484597,0.2626466181221558,0.18287360405382397,0.7443925370224047,-1.1840822292813866,0.006232385460175731,1.0181828688945016,-0.29087223037784743,-0.26191492372509495,-0.4827041033346785,0.5083924363167223,0.8768903817981308,-0.6656209926480597,-0.1758980318826104,1.1789557953519179,0.8887920767692477,2.0046582599512432,-0.6501537901627932,1.0529953384136446,1.5844831960754728,1.2912412532455868,0.9243566825638713,0.9597126649630634,3.6218978537046036,3.1269576003524127,1.914836320811382,-1.0832000643272819,-0.1333611726485954,1.7930143140179442,0.19624424562674062,0.2889999091039554,1.2241190154546975,-0.6966810077118192,0.7077431607617762,-0.712274316441883,0.49570894697737444,1.0065340223336994,1.954917564819329,0.08841928230327178,-0.6193437716665054,0.43188252856076326,1.488287926722168,2.054004469715688,0.49570894697737444,0.08841928230327178,-0.2331011456054219,1.4124116297329234,-0.14750568765470307,1.904775442700116,1.7724755011768645,2.034312887492732,1.1105747746411097,-0.36390379043786164,0.22289491850198123,1.4341867150381478,0.11556131040259485,1.37960291235598,2.435348044661633,0.9831687287835464,0.7565593617275889,-0.3933759714785898,0.4190345519703002,2.4445910304154994,0.44470276814533355,-0.5582145656983658,2.199742892007449,2.360911550267849,0.5083924363167223
3,040
Inner mitochondrial membrane protein complex
36
75
4.397475
0.000011
Q9UDW1,Q96IX5,P06576,O60830,Q99595,Q9H4I9,Q86Y39,P13073,P62072,O43676,O75438,O75306,Q53H12,O96000,P00846,Q13505,O75431,P51970,Q8IYU8,Q96CU9,P12236,Q9Y584,P03886,Q9P0J0,P24539,P22695,P56134,P56378,O14925,O95168,O14949,Q5XKP0,O75964,P14406,Q9Y512,Q9BUR5
Localization
GO Cellular component
msigdb_gocc
2,518,387,5,6,16,145,398,29,32,290,413,548,545,34,39,169,556,435,55,314,60,187,451,322,67,454,326,202,459,84,212,90,91,498,116
948,702,202,84,32,5,1030,413,169,290,1171,1032,90,459,1070,545,731,34,187,387,1694,2034,314,398,91,2203,2717,861,1318,67,322,1979,2985,2719,1225,1534,1187,2435,1320,2721,556,454,326,1001,29,39,2694,1279,672,566,548,212,1126,145,435,1358,55,518,6,1111,659,116,16,1260,689,902,633,451,2,1792,1950,1068,498,60,2430
0.2626466181221558,0.5336786310815371,1.6372812858760162,2.3139372650206984,2.9588343365432377,3.5833547818711566,0.19624424562674062,0.9831687287835464,1.7930143140179442,1.3355820397418836,0.0748011186548802,0.19624424562674062,2.276103138392118,0.8887920767692477,0.15604096067010367,0.7443925370224047,0.49570894697737444,2.9075240878120137,1.6896303788651301,1.0298093080175974,-0.26191492372509495,-0.45277442063761514,1.2577726487807976,1.0065340223336994,2.276103138392118,-0.5430331465710542,-0.9514247127867999,0.3543739888991153,-0.021421189614910855,2.453820478435673,1.2241190154546975,-0.4229989506921864,-1.680384786537059,-0.9514247127867999,0.033756111184921174,-0.1616845798336536,0.061151309647997754,-0.6966810077118192,-0.021421189614910855,-0.9514247127867999,0.7199845468995671,0.9006702914867534,1.2128596333356767,0.22289491850198123,3.0266138343517364,2.7598629433409028,-0.9189528352734494,0.006232385460175731,0.57140782105902,0.7077431607617762,0.7443925370224047,1.5950791374165418,0.11556131040259485,1.944921479987834,0.9361650584683445,-0.04920595720837689,2.5996850958566853,0.7808192166024813,3.575618702542787,0.1290854902149427,0.5964286373641703,2.1127087039343455,3.2175824750230393,0.020010396372018485,0.5588579410317828,0.31523626177182246,0.6337642954290207,0.9125251267176329,3.7813362177920875,-0.30540519590093435,-0.3933759714785898,0.16947255944840645,0.8290467604251529,2.4997661556800703,-0.6811299828485751
3,040
Protein localization
41
71
4.110493
0.000039
Q10713,P06576,O75381,O60830,Q99595,Q15388,Q9Y5J9,Q9NS69,O43808,Q15067,Q5JRX3,O15254,Q9Y5Y5,P62072,Q13505,O75431,Q8N4H5,O43765,P50402,P40855,P28288,P09601,P12236,Q3ZCQ8,Q9Y584,P05067,Q9UJS0,O14925,P46379,O14734,O43615,Q13190,P12235,P51648,P21796,Q9NR77,O96008,Q96B49,O43681,O60220,Q9Y512
Processes and pathways
Reactome Pathways
msigdb_reactome
131,387,130,5,6,394,264,9,390,265,526,151,289,29,39,169,49,433,565,181,183,56,314,566,60,73,464,202,335,465,340,217,345,94,96,225,601,102,612,233,498
858,465,202,151,340,612,433,390,233,5,130,2746,169,1297,2475,880,661,967,601,73,387,1694,2925,56,2805,345,314,2103,96,1241,1979,183,2435,181,335,565,823,94,1536,1696,29,131,1456,217,39,265,394,566,526,49,1683,757,1987,102,6,2696,2246,1260,225,9,633,1947,947,464,1792,2338,498,60,264,2909,289
0.3543739888991153,0.8768903817981308,1.6372812858760162,1.914836320811382,1.1562476399214794,0.6461578360344038,0.9361650584683445,1.0181828688945016,1.509795357420363,3.5833547818711566,2.0145588418698184,-0.984083002121523,1.7930143140179442,-0.007578087459911156,-0.7279101605274243,0.3283109386072143,0.5839313463784181,0.24942576442222106,0.6585257316553426,2.4168212862539087,1.0298093080175974,-0.26191492372509495,-1.338869380346214,2.5906665227871963,-1.0665598073816422,1.1448616242246488,1.2577726487807976,-0.4827041033346785,2.247577005884701,0.020010396372018485,-0.4229989506921864,1.7311919224355028,-0.6966810077118192,1.74153871768061,1.1789557953519179,0.7077431607617762,0.4061587071946509,2.2571001484359003,-0.1616845798336536,-0.26191492372509495,3.0266138343517364,2.0145588418698184,-0.11925085360259,1.5844831960754728,2.7598629433409028,1.401494945074417,1.0181828688945016,0.7077431607617762,0.7687015520901122,2.6445862744892894,-0.24749019058283162,0.48299836247200467,-0.4229989506921864,2.218920411804227,3.575618702542787,-0.9189528352734494,-0.5582145656983658,0.020010396372018485,1.5525853052037832,3.4820604215174513,0.6337642954290207,-0.3933759714785898,0.2758379519036087,0.8887920767692477,-0.30540519590093435,-0.6193437716665054,0.8290467604251529,2.4997661556800703,1.4124116297329234,-1.269549423261982,1.3466170528239039
3,040
Transporter activity
85
165
3.968916
0.000072
Q9UDW1,O60830,Q99595,Q9H2D1,Q9NS69,P49755,Q8TDW0,Q9BSK2,O43676,P00846,O96000,Q14849,P51970,Q9HC21,O95202,Q9Y619,Q70HW3,Q9C0H2,P05023,P36543,Q9Y584,P04062,Q9UNF0,Q8N697,Q6NUK1,O15173,P51790,O75964,P21796,Q9HC07,O96008,Q9UBX3,O43681,Q9Y487,O00400,P17900,P53985,P45880,L0R6Q1,Q8N4V1,Q93050,Q9HD20,Q8TB61,Q96GC9,P28288,Q96SU4,P03886,Q9Y277,Q13423,O14925,Q9H2V7,Q14728,Q7KZN9,O15118,P38435,Q8WTV0,Q9Y5J9,P16615,Q99808,O75438,Q9H936,Q6P4A7,Q6PML9,P12236,P24539,O43826,P12235,Q8NE01,P98194,Q7L0J3,Q9H2C2,P06576,Q15388,O43808,Q03518,P13073,O75306,Q99567,Q9P0J0,P56134,Q9UJS0,O95168,Q9H0U3,Q99797,Q8NEW0
Functions
GO Molecular function
msigdb_gomf
2,5,6,8,9,547,550,33,32,34,545,43,556,561,50,52,53,54,563,564,60,63,66,588,82,81,596,90,96,97,601,104,612,105,109,111,628,123,140,143,146,150,157,175,183,184,187,199,204,202,213,218,222,238,239,255,264,274,286,290,296,311,312,314,322,332,345,363,364,370,372,387,394,390,404,398,413,442,451,454,464,459,487,495,492
140,2757,109,948,702,202,238,81,32,612,1504,390,332,5,811,1030,413,290,1171,880,1032,90,967,459,50,1070,1046,545,601,731,34,187,63,563,653,387,1893,1844,749,732,1694,871,2034,750,345,314,398,274,111,2717,935,861,1644,2433,96,2552,322,1979,183,2985,1225,1187,564,239,2434,1189,123,1320,2252,547,2721,596,754,556,716,1368,895,628,896,454,1001,1411,1020,828,364,849,1302,2256,736,404,790,204,2963,218,1873,43,394,1542,2694,1279,3007,1158,82,2443,311,312,53,222,370,3029,1462,143,588,863,1683,363,1358,492,157,550,255,146,1053,175,641,184,442,6,495,286,2568,33,1164,1523,1009,54,487,372,8,213,1287,296,1548,97,561,150,3017,9,451,820,104,2,846,1712,464,795,66,199,105,60,264,1292,52,1690,2430
1.964897593179475,-1.0004827835760666,2.170865945299008,0.2626466181221558,0.5336786310815371,1.6372812858760162,1.4990510731461264,2.351544747161577,2.9588343365432377,0.6461578360344038,-0.14750568765470307,1.0181828688945016,1.1902781082588905,3.5833547818711566,0.4190345519703002,0.19624424562674062,0.9831687287835464,1.3355820397418836,0.0748011186548802,0.3283109386072143,0.19624424562674062,2.276103138392118,0.24942576442222106,0.8887920767692477,2.635631465461991,0.15604096067010367,0.18287360405382397,0.7443925370224047,0.6585257316553426,0.49570894697737444,2.9075240878120137,1.6896303788651301,2.4814280266167166,0.7077431607617762,0.5964286373641703,1.0298093080175974,-0.3786211358393844,-0.3492237281963389,0.48299836247200467,0.49570894697737444,-0.26191492372509495,0.3413568016183609,-0.45277442063761514,0.48299836247200467,1.1448616242246488,1.2577726487807976,1.0065340223336994,1.3686274111665022,2.151540289571206,-0.9514247127867999,0.2758379519036087,0.3543739888991153,-0.2331011456054219,-0.6966810077118192,2.247577005884701,-0.7908840017599092,1.2241190154546975,-0.4229989506921864,1.7311919224355028,-1.680384786537059,0.033756111184921174,0.061151309647997754,0.7077431607617762,1.4990510731461264,-0.6966810077118192,0.061151309647997754,2.0834256614858373,-0.021421189614910855,-0.5734361048340421,0.7443925370224047,-0.9514247127867999,0.6708680977120229,0.48299836247200467,0.7199845468995671,0.5210489561099639,-0.06314796381553464,0.31523626177182246,0.6337642954290207,0.31523626177182246,0.9006702914867534,0.22289491850198123,-0.09113208586471662,0.2095846341582732,0.39325486209580973,1.0760928564449042,0.36736263752585335,-0.007578087459911156,-0.5734361048340421,0.49570894697737444,1.0065340223336994,0.44470276814533355,1.6372812858760162,-1.4801308573975738,1.5844831960754728,-0.36390379043786164,2.706918315651424,1.0181828688945016,-0.1616845798336536,-0.9189528352734494,0.006232385460175731,-1.9267497642243225,0.08841928230327178,2.351544747161577,-0.6966810077118192,1.2689492993639755,1.2689492993639755,2.6086908370116504,1.5632363492107093,1.0645551154147626,-4.121259331308975,-0.11925085360259,1.954917564819329,0.6831850488258874,0.3543739888991153,-0.24749019058283162,1.0876086528881501,-0.04920595720837689,0.8410433975918085,1.8643679316323016,0.7443925370224047,1.4341867150381478,1.944921479987834,0.18287360405382397,1.7724755011768645,0.6213449936127172,1.7208277548364277,0.9243566825638713,3.575618702542787,0.8410433975918085,1.3466170528239039,-0.7908840017599092,2.933230716402563,0.08841928230327178,-0.14750568765470307,0.22289491850198123,2.6086908370116504,0.8530161446660425,1.0645551154147626,3.4977473541425774,1.5950791374165418,0.006232385460175731,1.3134519523684933,-0.1616845798336536,2.247577005884701,0.7199845468995671,1.9248809148764459,-2.412780764474814,3.4820604215174513,0.9125251267176329,0.4190345519703002,2.199742892007449,3.7813362177920875,0.3803228835675519,-0.26191492372509495,0.8887920767692477,0.44470276814533355,2.4630364318801337,1.6582743358244223,2.199742892007449,2.4997661556800703,1.4124116297329234,0.006232385460175731,2.617683785993935,-0.24749019058283162,-0.6811299828485751
3,040
Establishment of protein localization to membrane
34
88
3.895196
0.000098
Q4J6C6,Q9Y5J9,Q9NS69,P43307,Q8N4V1,Q9GZY8,Q9NPA0,Q9HD20,Q96A33,Q9Y5Y5,P62072,Q53H12,Q15041,O43765,P40855,Q15907,Q9Y584,O60725,O00560,O14737,Q15006,Q9P0J0,Q15629,P61026,P46379,Q99442,P27105,O60220,O15118,Q13277,P98194,Q9Y512,Q8N8Q8,Q15070
Processes and pathways
GO Biological process
msigdb_gobp
254,264,9,14,143,530,273,150,154,289,29,548,425,433,181,308,60,61,190,317,439,451,79,469,335,342,221,233,238,365,364,498,248,120
2056,1951,190,317,890,238,2059,612,433,233,61,2132,2368,967,1172,2576,1798,2480,765,221,2926,2397,799,2943,2280,181,2156,14,335,2616,1480,823,1153,1897,1696,2206,2109,469,1020,29,2619,364,1302,1106,365,1630,439,425,1541,120,79,1123,308,254,1157,548,1036,1631,143,1160,248,1683,2262,154,1686,342,530,1767,1663,712,746,569,150,273,9,451,846,1552,1737,1343,1344,1792,1891,498,60,264,2909,289
-0.46771987659621755,-0.40816850621130574,1.6791960809837663,1.2465754397744402,0.31523626177182246,1.4990510731461264,-0.46771987659621755,0.6461578360344038,0.9361650584683445,1.509795357420363,2.4906037531718463,-0.4977273208231059,-0.6501537901627932,0.24942576442222106,0.0748011186548802,-0.8067363769252331,-0.31997463365124035,-0.7279101605274243,0.4702605562765458,1.5632363492107093,-1.338869380346214,-0.6656209926480597,0.43188252856076326,-1.3738525898967593,-0.5886979958768187,1.74153871768061,-0.5127897509611888,3.25835762322235,1.1789557953519179,-0.8385736772120257,-0.1333611726485954,0.4061587071946509,0.08841928230327178,-0.3786211358393844,-0.26191492372509495,-0.5430331465710542,-0.4827041033346785,0.8768903817981308,0.2095846341582732,3.0266138343517364,-0.8385736772120257,1.0760928564449042,-0.007578087459911156,0.1290854902149427,1.0760928564449042,-0.21874759683495115,0.9243566825638713,0.9597126649630634,-0.1616845798336536,2.0932019556415513,2.360911550267849,0.11556131040259485,1.280105473646303,1.4341867150381478,0.08841928230327178,0.7443925370224047,0.19624424562674062,-0.21874759683495115,1.954917564819329,0.08841928230327178,1.477505845798672,-0.24749019058283162,-0.5734361048340421,1.904775442700116,-0.24749019058283162,1.1562476399214794,0.7687015520901122,-0.29087223037784743,-0.2331011456054219,0.5336786310815371,0.49570894697737444,0.7077431607617762,1.9248809148764459,1.37960291235598,3.4820604215174513,0.9125251267176329,0.3803228835675519,-0.1616845798336536,-0.2763755385948963,-0.03529708956303091,-0.03529708956303091,-0.30540519590093435,-0.36390379043786164,0.8290467604251529,2.4997661556800703,1.4124116297329234,-1.269549423261982,1.3466170528239039
3,040
Cation transmembrane transporter activity
31
65
3.866157
0.000111
Q9UDW1,P06576,O43808,Q8N4V1,Q93050,P16615,Q9HD20,P13073,Q99808,P00846,Q9H936,Q9HC21,O95202,Q9Y619,Q70HW3,Q6PML9,P05023,P36543,P24539,P56134,Q8N697,Q13423,P12235,O75964,Q7KZN9,Q9HC07,Q9H0U3,Q9Y487,Q8NEW0,O00400,P98194
Functions
GO Molecular function
msigdb_gomf
2,387,390,143,146,274,150,398,286,34,296,561,50,52,53,312,563,564,322,454,588,204,345,90,222,97,487,105,492,109,364
109,702,1504,390,1032,90,50,731,34,563,653,387,1893,1844,732,1694,2034,345,398,274,935,861,1644,2433,322,1979,1225,1187,564,2434,1320,596,896,454,1001,1411,1020,364,849,1302,204,1542,312,53,222,143,588,1358,492,146,1053,286,487,296,1548,97,561,150,820,2,1712,795,105,1292,52
2.170865945299008,0.5336786310815371,-0.14750568765470307,1.0181828688945016,0.19624424562674062,2.276103138392118,2.635631465461991,0.49570894697737444,2.9075240878120137,0.7077431607617762,0.5964286373641703,1.0298093080175974,-0.3786211358393844,-0.3492237281963389,0.49570894697737444,-0.26191492372509495,-0.45277442063761514,1.1448616242246488,1.0065340223336994,1.3686274111665022,0.2758379519036087,0.3543739888991153,-0.2331011456054219,-0.6966810077118192,1.2241190154546975,-0.4229989506921864,0.033756111184921174,0.061151309647997754,0.7077431607617762,-0.6966810077118192,-0.021421189614910855,0.6708680977120229,0.31523626177182246,0.9006702914867534,0.22289491850198123,-0.09113208586471662,0.2095846341582732,1.0760928564449042,0.36736263752585335,-0.007578087459911156,1.6372812858760162,-0.1616845798336536,1.2689492993639755,2.6086908370116504,1.5632363492107093,1.954917564819329,0.6831850488258874,-0.04920595720837689,0.8410433975918085,1.944921479987834,0.18287360405382397,1.3466170528239039,0.8530161446660425,1.3134519523684933,-0.1616845798336536,2.247577005884701,0.7199845468995671,1.9248809148764459,0.4190345519703002,3.7813362177920875,-0.26191492372509495,0.44470276814533355,2.199742892007449,0.006232385460175731,2.617683785993935
3,040
Inorganic molecular entity transmembrane transporter activity
40
71
3.853361
0.000117
Q9UDW1,P06576,Q8N4V1,P05141,Q93050,P16615,Q9HD20,P13073,Q8TDW0,P00846,Q9H936,O95202,Q9C0H2,P05023,P36543,P24539,P56134,Q8N697,O14548,Q13423,Q9Y277,O43826,P51790,P12235,O75964,Q7KZN9,P21796,Q9HC07,Q02978,Q9H0U3,P08195,Q9UBX3,Q9Y487,O43681,P00403,Q99797,O00400,P98194,P45880,Q96S66
Functions
GO Molecular function
msigdb_gomf
2,387,143,653,146,274,150,398,550,34,296,50,54,563,564,322,454,588,702,204,199,332,596,345,90,222,96,97,736,487,732,104,105,612,731,495,109,364,123,641
2757,109,702,612,332,1032,90,50,731,34,563,653,387,1893,1844,732,1694,871,2034,345,398,274,935,861,1644,2433,96,322,1979,1225,1187,564,2434,123,1320,596,754,896,454,1001,1411,1020,364,849,1302,736,204,3007,222,143,588,1358,550,146,1053,641,495,54,487,296,97,150,820,104,2,1712,795,199,105,1292,1690
-1.0004827835760666,2.170865945299008,0.5336786310815371,0.6461578360344038,1.1902781082588905,0.19624424562674062,2.276103138392118,2.635631465461991,0.49570894697737444,2.9075240878120137,0.7077431607617762,0.5964286373641703,1.0298093080175974,-0.3786211358393844,-0.3492237281963389,0.49570894697737444,-0.26191492372509495,0.3413568016183609,-0.45277442063761514,1.1448616242246488,1.0065340223336994,1.3686274111665022,0.2758379519036087,0.3543739888991153,-0.2331011456054219,-0.6966810077118192,2.247577005884701,1.2241190154546975,-0.4229989506921864,0.033756111184921174,0.061151309647997754,0.7077431607617762,-0.6966810077118192,2.0834256614858373,-0.021421189614910855,0.6708680977120229,0.48299836247200467,0.31523626177182246,0.9006702914867534,0.22289491850198123,-0.09113208586471662,0.2095846341582732,1.0760928564449042,0.36736263752585335,-0.007578087459911156,0.49570894697737444,1.6372812858760162,-1.9267497642243225,1.5632363492107093,1.954917564819329,0.6831850488258874,-0.04920595720837689,0.7443925370224047,1.944921479987834,0.18287360405382397,0.6213449936127172,0.8410433975918085,2.6086908370116504,0.8530161446660425,1.3134519523684933,2.247577005884701,1.9248809148764459,0.4190345519703002,2.199742892007449,3.7813362177920875,-0.26191492372509495,0.44470276814533355,1.6582743358244223,2.199742892007449,0.006232385460175731,-0.24749019058283162
3,040
Outer membrane
41
88
3.852713
0.000117
O95140,Q9NZ45,Q9Y371,Q15388,Q9BWH2,Q9NS69,Q8WXH0,Q9GZY8,Q8WY22,O43169,Q53H12,O60313,Q16891,Q9NZJ7,Q13505,O75431,Q9NQZ5,P57105,Q8N4H5,P50402,Q9HCL2,P09601,Q9Y6C9,Q9Y277,O00264,Q9NUQ2,Q5XKP0,Q6NUM9,O00165,P21796,O96008,Q96B49,Q9NXE4,Q9Y512,Q9BUR5,Q9NVT9,Q9UKU0,Q9NX63,P45880,Q7Z434,P33121
Localization
GO Cellular component
msigdb_gocc
636,3,389,394,263,9,657,530,20,26,548,292,672,166,39,169,302,46,49,565,445,56,192,199,201,338,212,341,473,96,601,102,496,498,116,503,249,633,123,640,637
473,201,1096,3031,26,292,1617,1976,169,967,636,1172,601,933,2989,1815,56,1978,96,637,2435,800,2036,123,565,862,1101,2074,46,2349,790,909,39,1855,394,2753,672,548,212,341,1126,640,1007,841,1024,1632,49,886,1683,757,1008,657,20,1763,102,1806,962,866,1419,1111,2964,2879,116,1164,263,530,989,445,1526,302,9,338,1329,689,503,760,633,496,3,166,1736,1234,721,249,199,389,498,192
0.864965105135409,1.6372812858760162,0.1290854902149427,-4.300105735849686,3.0434471989282343,1.3245270326423748,-0.21874759683495115,-0.4229989506921864,1.7930143140179442,0.24942576442222106,0.6213449936127172,0.0748011186548802,0.6585257316553426,0.2758379519036087,-1.6989519184329778,-0.33458074379489317,2.5906665227871963,-0.4229989506921864,2.247577005884701,0.6213449936127172,-0.6966810077118192,0.43188252856076326,-0.45277442063761514,2.0834256614858373,0.7077431607617762,0.3543739888991153,0.1290854902149427,-0.46771987659621755,2.6713750460920487,-0.634728130674405,0.44470276814533355,0.3021326319906221,2.7598629433409028,-0.3492237281963389,1.0181828688945016,-0.984083002121523,0.57140782105902,0.7443925370224047,1.5950791374165418,1.1562476399214794,0.11556131040259485,0.6213449936127172,0.22289491850198123,0.3803228835675519,0.2095846341582732,-0.21874759683495115,2.6445862744892894,0.3283109386072143,-0.24749019058283162,0.48299836247200467,0.22289491850198123,0.5964286373641703,3.1269576003524127,-0.29087223037784743,2.218920411804227,-0.31997463365124035,0.2626466181221558,0.3543739888991153,-0.09113208586471662,0.1290854902149427,-1.4801308573975738,-1.1840822292813866,2.1127087039343455,0.08841928230327178,1.4124116297329234,0.7687015520901122,0.23617524638555046,0.9243566825638713,-0.14750568765470307,1.302356719279247,3.4820604215174513,1.1789557953519179,-0.021421189614910855,0.5588579410317828,0.8170261289828668,0.48299836247200467,0.6337642954290207,0.8410433975918085,3.652568931069314,1.813485136764922,-0.2763755385948963,0.033756111184921174,0.5210489561099639,1.477505845798672,1.6582743358244223,1.0298093080175974,0.8290467604251529,1.6791960809837663
3,040
Protein targeting
45
107
3.784705
0.000154
Q10713,O75381,O60830,Q99595,Q9Y371,Q9Y5J9,Q9NS69,Q15388,Q5JRX3,P43307,P51572,Q9GZY8,O95831,O43464,Q9Y5Y5,P62072,Q53H12,O95429,Q15041,P57105,Q8N4H5,O43765,P40855,Q9H9H4,Q9Y584,O60725,Q3ZCQ8,O00560,O14737,Q9P0J0,O14925,Q15629,Q9Y5M8,P46379,Q99442,O43615,O00165,P27105,O96008,O43681,Q99797,O60220,Q9Y512,P55786,Q14108
Processes and pathways
GO Biological process
msigdb_gobp
131,130,5,6,389,264,9,394,526,14,391,530,23,408,289,29,548,421,425,46,49,433,181,569,60,61,566,190,317,451,202,79,80,335,342,340,473,221,601,612,495,233,498,247,124
2056,473,1951,190,2875,317,202,949,408,340,612,433,233,61,5,1237,130,1297,2368,967,636,421,1776,23,601,2576,1798,2480,2805,906,1868,2232,221,2067,2417,2397,799,1508,2943,2280,181,14,335,817,1480,823,1153,391,247,46,1696,882,2109,1020,1820,29,1118,2777,1801,1676,1302,131,124,613,425,394,79,2753,665,566,548,526,803,1080,2121,1631,49,757,2262,962,342,718,2222,6,495,530,1663,569,1260,1467,9,451,2269,846,1552,1737,946,947,836,389,1891,498,60,264,2909,80,289
-0.46771987659621755,0.864965105135409,-0.40816850621130574,1.6791960809837663,-1.1840822292813866,1.2465754397744402,1.6372812858760162,0.2626466181221558,0.9948626739598494,1.1562476399214794,0.6461578360344038,0.9361650584683445,1.509795357420363,2.4906037531718463,3.5833547818711566,0.020010396372018485,2.0145588418698184,-0.007578087459911156,-0.6501537901627932,0.24942576442222106,0.6213449936127172,0.9714520911959001,-0.30540519590093435,3.085338247748161,0.6585257316553426,-0.8067363769252331,-0.31997463365124035,-0.7279101605274243,-1.0665598073816422,0.3021326319906221,-0.36390379043786164,-0.5582145656983658,1.5632363492107093,-0.46771987659621755,-0.6811299828485751,-0.6656209926480597,0.43188252856076326,-0.14750568765470307,-1.3738525898967593,-0.5886979958768187,1.74153871768061,3.25835762322235,1.1789557953519179,0.4190345519703002,-0.1333611726485954,0.4061587071946509,0.08841928230327178,1.0181828688945016,1.477505845798672,2.6713750460920487,-0.26191492372509495,0.3283109386072143,-0.4827041033346785,0.2095846341582732,-0.33458074379489317,3.0266138343517364,0.11556131040259485,-1.0169300525091258,-0.31997463365124035,-0.24749019058283162,-0.007578087459911156,2.0145588418698184,2.0834256614858373,0.6461578360344038,0.9597126649630634,1.0181828688945016,2.360911550267849,-0.984083002121523,0.5839313463784181,0.7077431607617762,0.7443925370224047,0.7687015520901122,0.43188252856076326,0.15604096067010367,-0.4827041033346785,-0.21874759683495115,2.6445862744892894,0.48299836247200467,-0.5734361048340421,0.2626466181221558,1.1562476399214794,0.5210489561099639,-0.5430331465710542,3.575618702542787,0.8410433975918085,0.7687015520901122,-0.2331011456054219,0.7077431607617762,0.020010396372018485,-0.11925085360259,3.4820604215174513,0.9125251267176329,-0.5734361048340421,0.3803228835675519,-0.1616845798336536,-0.2763755385948963,0.2758379519036087,0.2758379519036087,0.39325486209580973,1.0298093080175974,-0.36390379043786164,0.8290467604251529,2.4997661556800703,1.4124116297329234,-1.269549423261982,2.360911550267849,1.3466170528239039
3,040
Anion transport
44
65
3.743973
0.000181
Q9H2D1,O43808,P05141,P07602,Q8TB61,Q99808,Q8TDW0,Q9NZJ7,Q15041,Q9H936,P54105,Q9HC21,O75915,Q9Y619,Q15907,Q9C0H2,P28288,P12236,Q08722,Q8N697,Q9Y277,Q9UJS0,O43826,Q6NUK1,Q9NP80,P51790,P12235,Q14728,Q86WC4,P21796,O60831,Q02978,P08195,Q9UBX3,O43681,P14174,O00400,P51798,Q7L0J3,P11166,Q9UHG3,P53985,P45880,Q96S66
Processes and pathways
GO Biological process
msigdb_gobp
8,390,653,155,157,286,550,166,425,296,299,561,681,52,308,54,183,314,323,588,199,464,332,82,214,596,345,218,95,96,224,736,732,104,612,106,109,754,370,750,121,628,123,641
2757,109,612,390,332,821,224,880,681,1046,2229,653,1269,155,749,732,871,750,345,314,106,2104,96,183,1189,123,596,754,895,628,299,896,849,736,323,218,425,1541,1542,308,3007,82,2443,370,95,588,157,550,641,286,54,2624,8,296,1548,561,214,166,104,121,464,199,1891,52,1690
-1.0004827835760666,2.170865945299008,0.6461578360344038,1.0181828688945016,1.1902781082588905,0.4061587071946509,1.5525853052037832,0.3283109386072143,0.5588579410317828,0.18287360405382397,-0.5582145656983658,0.5964286373641703,0.006232385460175731,1.8946982228718794,0.48299836247200467,0.49570894697737444,0.3413568016183609,0.48299836247200467,1.1448616242246488,1.2577726487807976,2.1901320481563595,-0.4827041033346785,2.247577005884701,1.7311919224355028,0.061151309647997754,2.0834256614858373,0.6708680977120229,0.48299836247200467,0.31523626177182246,0.6337642954290207,1.302356719279247,0.31523626177182246,0.36736263752585335,0.49570894697737444,1.2241190154546975,1.5844831960754728,0.9597126649630634,-0.1616845798336536,-0.1616845798336536,1.280105473646303,-1.9267497642243225,2.351544747161577,-0.6966810077118192,1.0645551154147626,2.2571001484359003,0.6831850488258874,1.8643679316323016,0.7443925370224047,0.6213449936127172,1.3466170528239039,2.6086908370116504,-0.8385736772120257,3.4977473541425774,1.3134519523684933,-0.1616845798336536,0.7199845468995671,1.5950791374165418,1.813485136764922,2.199742892007449,2.0932019556415513,0.8887920767692477,1.6582743358244223,-0.36390379043786164,2.617683785993935,-0.24749019058283162
3,040
Intrinsic component of endoplasmic reticulum membrane
28
54
3.666867
0.000246
Q15125,O95470,Q86YN1,P51572,P57088,Q8N4V1,Q9NPA0,Q03518,Q96A33,Q8TB61,Q15041,Q5H8A4,Q8TCT9,Q9P035,Q8TCT8,Q15006,Q9Y282,P27824,Q9NQC3,O43826,O75844,Q15629,Q99442,Q9BUN8,Q9Y4P3,Q92643,Q86XL3,Q12981
Localization
GO Cellular component
msigdb_gocc
4,261,12,391,403,143,273,404,154,157,425,295,40,173,185,439,65,453,71,332,77,79,342,110,115,371,243,377
1473,634,669,2059,332,77,475,261,905,813,575,2485,453,2523,391,403,1020,404,377,1725,439,425,4,79,1190,295,1036,686,243,12,143,1160,157,185,40,371,888,154,619,342,1879,110,1145,570,273,71,1165,173,2449,1234,795,65,115,1345
-0.1333611726485954,0.6213449936127172,0.57140782105902,-0.46771987659621755,1.1902781082588905,2.370264417454816,0.864965105135409,1.4124116297329234,0.3021326319906221,0.4190345519703002,0.6954766988270652,-0.7279101605274243,0.9006702914867534,-0.7593104723132084,1.0181828688945016,1.0065340223336994,0.2095846341582732,1.0065340223336994,1.0529953384136446,-0.2763755385948963,0.9243566825638713,0.9597126649630634,3.6218978537046036,2.360911550267849,0.061151309647997754,1.3134519523684933,0.19624424562674062,0.5588579410317828,1.488287926722168,3.3471659553996225,1.954917564819329,0.08841928230327178,1.8643679316323016,1.7104461511591396,2.7598629433409028,1.0645551154147626,0.3283109386072143,1.904775442700116,0.6461578360344038,1.1562476399214794,-0.36390379043786164,2.1612105866232185,0.10200596012172755,0.7077431607617762,1.37960291235598,2.435348044661633,0.08841928230327178,1.782753437123811,-0.6966810077118192,0.033756111184921174,0.44470276814533355,2.4814280266167166,2.1224392619869463,-0.03529708956303091
3,040
Mitochondrial transmembrane transport
23
49
3.652493
0.00026
P06576,O60830,Q15388,Q99595,Q9H2D1,Q9H4I9,O95831,Q9BSK2,P00846,Q9H936,O95202,Q8IYU8,Q9Y619,Q6P4A7,P12236,P23786,P24539,P56134,O14925,O43615,P12235,O75964,P21796
Processes and pathways
GO Biological process
msigdb_gobp
387,5,394,6,8,16,23,33,34,296,50,435,52,311,314,447,322,454,202,340,345,90,96
202,340,1504,5,811,1297,880,1032,90,967,50,1046,23,601,34,653,387,2805,345,314,96,447,322,1979,1187,1320,862,895,454,1001,849,394,566,311,435,1358,2310,6,659,33,8,16,296,1548,1260,464,1221,1068,52
1.6372812858760162,1.1562476399214794,-0.14750568765470307,3.5833547818711566,0.4190345519703002,-0.007578087459911156,0.3283109386072143,0.19624424562674062,2.276103138392118,0.24942576442222106,2.635631465461991,0.18287360405382397,3.085338247748161,0.6585257316553426,2.9075240878120137,0.5964286373641703,1.0298093080175974,-1.0665598073816422,1.1448616242246488,1.2577726487807976,2.247577005884701,0.9125251267176329,1.2241190154546975,-0.4229989506921864,0.061151309647997754,-0.021421189614910855,0.3543739888991153,0.31523626177182246,0.9006702914867534,0.22289491850198123,0.36736263752585335,1.0181828688945016,0.7077431607617762,1.2689492993639755,0.9361650584683445,-0.04920595720837689,-0.604000472797998,3.575618702542787,0.5964286373641703,2.933230716402563,3.4977473541425774,3.2175824750230393,1.3134519523684933,-0.1616845798336536,0.020010396372018485,0.8887920767692477,0.047469694504802575,0.16947255944840645,2.617683785993935
3,040
Intrinsic component of plasma membrane
46
73
3.597088
0.000322
Q8WTV0,O43657,P0DP25,Q9H1Z9,Q8N2K0,P51572,P05141,P16615,Q9UIQ6,Q9NR28,P35613,O43464,Q99808,Q8TDW0,O15498,Q99805,Q86UP2,P04439,P05023,O00560,Q08722,P10321,P27824,P05067,Q92542,O00264,Q9UJS0,P19022,Q9BTU6,P17152,P36551,P51790,Q00325,P12235,Q9Y639,O96005,P27105,Q02978,Q9H0U3,O95864,Q99797,O00400,O15118,O15121,P11166,P53985
Localization
GO Cellular component
msigdb_gocc
255,0,765,267,785,391,653,274,531,794,399,408,286,550,796,426,686,813,563,190,323,575,453,73,457,201,464,837,337,460,468,596,849,345,347,92,221,736,487,730,495,109,238,505,750,628
1473,201,109,190,1995,1403,238,505,796,408,0,730,92,905,2182,813,563,73,653,1269,765,575,750,1317,1925,345,274,460,837,935,2232,221,453,1534,399,468,1189,391,596,628,1102,896,849,736,982,323,1004,1457,1655,2165,2650,1542,686,785,863,1088,550,255,457,495,426,286,1830,337,487,267,794,2900,531,464,1791,2916,347
-0.1333611726485954,1.6372812858760162,2.170865945299008,1.6791960809837663,-0.43786751739574514,-0.09113208586471662,1.4990510731461264,0.8049813983798076,0.43188252856076326,0.9948626739598494,3.966214036312402,0.49570894697737444,2.266608843369935,0.3021326319906221,-0.5278916176011564,0.4190345519703002,0.7077431607617762,2.4168212862539087,0.5964286373641703,0.006232385460175731,0.4702605562765458,0.6954766988270652,0.48299836247200467,-0.021421189614910855,-0.3933759714785898,1.1448616242246488,1.3686274111665022,0.8887920767692477,0.3803228835675519,0.2758379519036087,-0.5582145656983658,1.5632363492107093,0.9006702914867534,-0.1616845798336536,1.0065340223336994,0.8768903817981308,0.061151309647997754,1.0181828688945016,0.6708680977120229,0.6337642954290207,0.1290854902149427,0.31523626177182246,0.36736263752585335,0.49570894697737444,0.23617524638555046,1.2241190154546975,0.22289491850198123,-0.11925085360259,-0.2331011456054219,-0.5127897509611888,-0.870589512103763,-0.1616845798336536,0.5588579410317828,0.45749540095397245,0.3543739888991153,0.1425786554172647,0.7443925370224047,1.4341867150381478,0.9006702914867534,0.8410433975918085,0.9597126649630634,1.3466170528239039,-0.33458074379489317,1.1789557953519179,0.8530161446660425,1.401494945074417,0.44470276814533355,-1.235206937204345,0.7687015520901122,0.8887920767692477,-0.30540519590093435,-1.2867995083685047,1.1334542001794992
3,040
Abnormal retinal artery morphology
10
21
3.569931
0.000357
P00846,P16278,Q9NZJ7,Q13510,P21964,P06865,P17900,Q9Y4P3,P10619,P07602
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
34,99,166,38,165,101,111,115,153,155
2572,2249,34,187,101,155,1204,153,2482,99,111,165,1535,1932,2350,38,1983,1517,166,2094,115
-0.8067363769252331,-0.5734361048340421,2.9075240878120137,1.6896303788651301,2.218920411804227,1.8946982228718794,0.047469694504802575,1.904775442700116,-0.7279101605274243,2.228487185887663,2.151540289571206,1.813485136764922,-0.1616845798336536,-0.3933759714785898,-0.634728130674405,2.7774136025275533,-0.4229989506921864,-0.14750568765470307,1.813485136764922,-0.46771987659621755,2.1224392619869463
3,040
Tetrapyrrole binding
11
16
3.484645
0.000493
Q6UW02,Q9NRV9,Q16850,O00264,Q8WUJ1,P53701,O15173,P09601,O43169,P30519,Q7KZN9
Functions
GO Molecular function
msigdb_gomf
358,418,170,201,432,178,81,56,26,27,222
201,81,26,1694,56,1072,27,178,170,358,222,432,927,1546,444,418
1.6372812858760162,2.351544747161577,3.0434471989282343,-0.26191492372509495,2.5906665227871963,0.15604096067010367,3.0350360441668323,1.7621804442172937,1.7930143140179442,1.099102595545742,1.5632363492107093,0.9479503532206887,0.2889999091039554,-0.1616845798336536,0.9243566825638713,0.9831687287835464
3,040
Carbohydrate derivative transport
16
19
3.462154
0.000536
Q8WTV0,Q8TDW0,Q08722,Q9NZJ7,Q8N697,O43808,O43826,L0R6Q1,O00400,Q9HC21,Q6NUK1,P12235,P12236,P07602,Q8TB61,Q99808
Processes and pathways
GO Biological process
msigdb_gobp
255,550,323,166,588,390,332,140,109,561,82,345,314,155,157,286
140,109,390,332,653,155,345,314,1189,828,323,82,588,157,550,255,286,561,166
1.964897593179475,2.170865945299008,1.0181828688945016,1.1902781082588905,0.5964286373641703,1.8946982228718794,1.1448616242246488,1.2577726487807976,0.061151309647997754,0.39325486209580973,1.2241190154546975,2.351544747161577,0.6831850488258874,1.8643679316323016,0.7443925370224047,1.4341867150381478,1.3466170528239039,0.7199845468995671,1.813485136764922
3,040
Sphingolipid metabolic process
19
29
3.453159
0.000554
O95470,P50897,Q96G23,O43464,P07602,Q9NZJ7,Q13510,Q99805,Q9P035,P06280,P04062,Q06136,P16278,P06865,Q9NXE4,P17900,Q9H2C2,O15121,O15269
Processes and pathways
GO Biological process
msigdb_gobp
261,15,147,408,155,166,38,426,173,313,63,461,99,101,496,111,372,505,245
505,245,903,408,261,63,313,101,155,1204,99,111,2552,848,1646,15,1322,461,38,548,772,147,426,372,496,1165,166,173,1947
0.8049813983798076,1.477505845798672,0.3021326319906221,0.9948626739598494,1.4124116297329234,2.4814280266167166,1.2577726487807976,2.218920411804227,1.8946982228718794,0.047469694504802575,2.228487185887663,2.151540289571206,-0.7908840017599092,0.36736263752585335,-0.2331011456054219,3.2339235068205605,-0.021421189614910855,0.8887920767692477,2.7774136025275533,0.7443925370224047,0.4702605562765458,1.944921479987834,0.9597126649630634,1.0645551154147626,0.8410433975918085,0.08841928230327178,1.813485136764922,1.782753437123811,-0.3933759714785898
3,040
Steroid binding
10
22
3.447232
0.000566
P21796,Q14849,O00264,O15118,P38435,O15173,Q96SU4,P45880,Q14108,P04062
Functions
GO Molecular function
msigdb_gomf
96,43,201,238,239,81,184,123,124,63
201,238,81,2131,1531,269,63,563,1844,96,2552,1241,645,239,123,828,124,43,184,1523,1009,1287
1.6372812858760162,1.4990510731461264,2.351544747161577,-0.4977273208231059,-0.1616845798336536,1.3905587313935528,2.4814280266167166,0.7077431607617762,-0.3492237281963389,2.247577005884701,-0.7908840017599092,0.020010396372018485,0.6088998135451131,1.4990510731461264,2.0834256614858373,0.39325486209580973,2.0834256614858373,2.706918315651424,1.7208277548364277,-0.14750568765470307,0.22289491850198123,0.006232385460175731
3,040
Abnormality of head blood vessel
10
24
3.431079
0.000601
P00846,P16278,Q9NZJ7,Q13510,P21964,P06865,P17900,Q9Y4P3,P10619,P07602
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
34,99,166,38,165,101,111,115,153,155
1741,2572,2249,34,187,101,155,1204,153,2482,99,111,2104,165,1535,1047,1932,2350,38,1983,1517,166,2094,115
-0.29087223037784743,-0.8067363769252331,-0.5734361048340421,2.9075240878120137,1.6896303788651301,2.218920411804227,1.8946982228718794,0.047469694504802575,1.904775442700116,-0.7279101605274243,2.228487185887663,2.151540289571206,-0.4827041033346785,1.813485136764922,-0.1616845798336536,0.18287360405382397,-0.3933759714785898,-0.634728130674405,2.7774136025275533,-0.4229989506921864,-0.14750568765470307,1.813485136764922,-0.46771987659621755,2.1224392619869463
3,040
Cellular ion homeostasis
31
82
3.389309
0.000701
P06576,Q96HE7,Q8N511,P51572,P50897,Q9H4I9,Q9BPX6,Q93050,P16615,O75503,Q9HD20,Q96A33,Q16891,O43819,O95202,Q8IYU8,P05023,P09601,Q6PML9,P05067,Q92544,P51790,O75880,Q9Y639,O76024,Q9HC07,Q9Y487,Q8NEW0,P98194,Q7L0J3,Q96PU5
Processes and pathways
GO Biological process
msigdb_gobp
387,649,142,391,15,16,659,146,274,148,150,154,672,428,50,435,563,56,312,73,591,596,595,347,475,97,105,492,364,370,632
1951,2875,428,2100,691,811,148,595,2700,475,50,1619,1572,2182,563,73,387,1204,1844,2134,56,871,765,2716,1573,1071,274,2759,935,2035,1869,2417,2485,1959,1622,2434,2372,15,1153,391,596,1819,1102,896,1411,1118,919,1822,364,1302,1679,2165,1123,672,312,370,911,435,142,1358,492,591,146,154,1606,649,632,866,659,1860,16,97,150,820,1737,1712,1221,795,105,1068,347,1690
-0.40816850621130574,-1.1840822292813866,0.9479503532206887,-0.4827041033346785,0.5462815850690601,0.4190345519703002,1.9349092822529808,0.6708680977120229,-0.9351656176172263,0.864965105135409,2.635631465461991,-0.21874759683495115,-0.19014622799961578,-0.5278916176011564,0.7077431607617762,2.4168212862539087,1.0298093080175974,0.047469694504802575,-0.3492237281963389,-0.4977273208231059,2.5906665227871963,0.3413568016183609,0.4702605562765458,-0.9514247127867999,-0.19014622799961578,0.15604096067010367,1.3686274111665022,-1.0004827835760666,0.2758379519036087,-0.45277442063761514,-0.36390379043786164,-0.6811299828485751,-0.7279101605274243,-0.40816850621130574,-0.21874759683495115,-0.6966810077118192,-0.6501537901627932,3.2339235068205605,0.08841928230327178,1.0181828688945016,0.6708680977120229,-0.33458074379489317,0.1290854902149427,0.31523626177182246,-0.09113208586471662,0.11556131040259485,0.2889999091039554,-0.33458074379489317,1.0760928564449042,-0.007578087459911156,-0.24749019058283162,-0.5127897509611888,0.11556131040259485,0.57140782105902,1.2689492993639755,1.0645551154147626,0.3021326319906221,0.9361650584683445,1.964897593179475,-0.04920595720837689,0.8410433975918085,0.6831850488258874,1.944921479987834,1.904775442700116,-0.20442935390032577,0.6088998135451131,0.6337642954290207,0.3543739888991153,0.5964286373641703,-0.3492237281963389,3.2175824750230393,2.247577005884701,1.9248809148764459,0.4190345519703002,-0.2763755385948963,-0.26191492372509495,0.047469694504802575,0.44470276814533355,2.199742892007449,0.16947255944840645,1.1334542001794992,-0.24749019058283162
3,040
Ceramide metabolic process
12
19
3.388799
0.000702
O95470,Q13510,P06865,Q99805,Q9NXE4,O15121,P17900,Q96G23,O43464,P06280,O15269,P04062
Processes and pathways
GO Biological process
msigdb_gobp
261,38,101,426,496,505,111,147,408,313,245,63
505,245,903,408,261,63,313,101,1204,111,848,1646,1322,38,548,772,147,426,496
0.8049813983798076,1.477505845798672,0.3021326319906221,0.9948626739598494,1.4124116297329234,2.4814280266167166,1.2577726487807976,2.218920411804227,0.047469694504802575,2.151540289571206,0.36736263752585335,-0.2331011456054219,-0.021421189614910855,2.7774136025275533,0.7443925370224047,0.4702605562765458,1.944921479987834,0.9597126649630634,0.8410433975918085
3,040
Golgi membrane
60
138
3.382408
0.000719
O15260,Q10713,Q9Y371,Q92896,O95197,P24390,Q5T9L3,O00461,P51572,L0R6Q1,Q8N4V1,Q15363,O95249,P35613,Q15392,Q9NTJ5,Q8NCH0,Q8TB61,Q9NRB3,P49755,Q6ZRP7,Q8IZA0,Q5T2E6,Q9BVK6,Q9H9E3,Q8TBA6,O43752,Q9H7Z7,Q7L5N7,Q9BXS4,Q9Y282,O15155,P10321,Q9P2W9,Q8NBN3,Q08AM6,P61026,Q10472,Q9Y3B3,Q7LGA3,Q13190,O43505,O95721,Q99640,Q9Y5U9,Q9HC07,O14653,Q86Y82,Q96L58,Q9NXE4,Q08378,O00400,P98194,Q9BUR5,Q8IV08,Q8TBQ9,O95070,O15258,Q14108,O43731
Localization
GO Cellular component
msigdb_gocc
128,131,389,517,135,10,11,138,391,140,143,19,523,399,152,541,28,157,417,547,160,168,558,559,560,300,51,444,567,579,65,321,575,69,70,587,469,210,87,88,217,348,476,354,356,97,481,484,493,496,500,109,364,116,117,501,118,379,124,127
140,109,138,787,2875,481,890,321,379,128,796,348,1185,127,2148,51,1223,704,1669,1170,118,135,523,1572,476,905,813,1977,871,575,750,1925,624,2552,10,1624,399,2703,1272,800,2001,2252,817,547,893,2877,391,596,894,1848,2420,1575,2254,2507,2206,724,469,1208,2460,1934,364,982,500,1209,587,1175,210,2161,131,1004,217,1458,124,984,2513,2165,19,1247,152,2167,1190,558,11,160,567,88,3029,2121,484,117,168,143,1037,70,28,805,157,300,501,1659,2017,517,2585,493,641,354,116,559,2125,579,1881,832,1113,712,444,746,560,1146,97,417,2247,541,496,1947,69,2932,1736,1737,2318,795,65,2654,2498,2850,389,87,356,1668
1.964897593179475,2.170865945299008,1.9848097046957438,0.44470276814533355,-1.1840822292813866,0.8530161446660425,0.31523626177182246,1.2241190154546975,1.0414134334695793,2.034312887492732,0.43188252856076326,1.1220252798248234,0.061151309647997754,2.0441664596066604,-0.5127897509611888,2.626663982355961,0.033756111184921174,0.5336786310815371,-0.24749019058283162,0.0748011186548802,2.0932019556415513,1.9947418992044237,0.7687015520901122,-0.19014622799961578,0.864965105135409,0.3021326319906221,0.4190345519703002,-0.4229989506921864,0.3413568016183609,0.6954766988270652,0.48299836247200467,-0.3933759714785898,0.6337642954290207,-0.7908840017599092,3.474202711443219,-0.21874759683495115,1.0065340223336994,-0.9351656176172263,0.006232385460175731,0.43188252856076326,-0.43786751739574514,-0.5734361048340421,0.4190345519703002,0.7443925370224047,0.31523626177182246,-1.1840822292813866,1.0181828688945016,0.6708680977120229,0.31523626177182246,-0.3492237281963389,-0.6811299828485751,-0.19014622799961578,-0.5734361048340421,-0.7435887937700587,-0.5430331465710542,0.5083924363167223,0.8768903817981308,0.047469694504802575,-0.712274316441883,-0.3933759714785898,1.0760928564449042,0.23617524638555046,0.8170261289828668,0.047469694504802575,0.6831850488258874,0.0748011186548802,1.6056568490181453,-0.5127897509611888,2.0145588418698184,0.22289491850198123,1.5844831960754728,-0.11925085360259,2.0834256614858373,0.23617524638555046,-0.7435887937700587,-0.5127897509611888,3.1269576003524127,0.020010396372018485,1.914836320811382,-0.5127897509611888,0.061151309647997754,0.7199845468995671,3.3471659553996225,1.8440649572883736,0.7077431607617762,2.2855830809653983,-4.121259331308975,-0.4827041033346785,0.8530161446660425,2.10296295242631,1.803258193474141,1.954917564819329,0.19624424562674062,2.435348044661633,3.0350360441668323,0.43188252856076326,1.8643679316323016,1.302356719279247,0.8170261289828668,-0.2331011456054219,-0.43786751739574514,0.7808192166024813,-0.8067363769252331,0.8410433975918085,0.6213449936127172,1.1105747746411097,2.1127087039343455,0.7199845468995671,-0.4827041033346785,0.6954766988270652,-0.36390379043786164,0.39325486209580973,0.1290854902149427,0.5336786310815371,0.9243566825638713,0.49570894697737444,0.7199845468995671,0.10200596012172755,2.247577005884701,0.9831687287835464,-0.5582145656983658,0.7565593617275889,0.8410433975918085,-0.3933759714785898,2.4445910304154994,-1.338869380346214,-0.2763755385948963,-0.2763755385948963,-0.604000472797998,0.44470276814533355,2.4814280266167166,-0.870589512103763,-0.7279101605274243,-1.1334162316136511,1.0298093080175974,2.2950487183120347,1.1105747746411097,-0.2331011456054219
3,040
Mitochondrial carrier domain superfamily [IPR023395]
12
20
3.338667
0.000842
Q9Y6C9,Q9BSK2,Q9NZJ7,Q9H2D1,Q9H936,O43808,Q9UBX3,Q6NUK1,Q9Y619,Q70HW3,P12235,P12236
Sequence
InterPro Superfamily
interpro_homologous_superfamily
192,33,166,8,296,390,104,82,52,53,345,314
1504,390,880,653,345,314,895,849,736,82,53,33,8,296,561,166,104,464,52,192
-0.14750568765470307,1.0181828688945016,0.3283109386072143,0.5964286373641703,1.1448616242246488,1.2577726487807976,0.31523626177182246,0.36736263752585335,0.49570894697737444,2.351544747161577,2.6086908370116504,2.933230716402563,3.4977473541425774,1.3134519523684933,0.7199845468995671,1.813485136764922,2.199742892007449,0.8887920767692477,2.617683785993935,1.6791960809837663
3,040
Mitochondrial substrate/solute carrier [IPR018108]
12
20
3.338667
0.000842
Q9Y6C9,Q9BSK2,Q9NZJ7,Q9H2D1,Q9H936,O43808,Q9UBX3,Q6NUK1,Q9Y619,Q70HW3,P12235,P12236
Sequence
InterPro Repeat
interpro_repeat
192,33,166,8,296,390,104,82,52,53,345,314
1504,390,880,653,345,314,895,849,736,82,53,33,8,296,561,166,104,464,52,192
-0.14750568765470307,1.0181828688945016,0.3283109386072143,0.5964286373641703,1.1448616242246488,1.2577726487807976,0.31523626177182246,0.36736263752585335,0.49570894697737444,2.351544747161577,2.6086908370116504,2.933230716402563,3.4977473541425774,1.3134519523684933,0.7199845468995671,1.813485136764922,2.199742892007449,0.8887920767692477,2.617683785993935,1.6791960809837663
3,040
SLC25 family of mitochondrial transporters
12
20
3.338667
0.000842
Q9Y6C9,Q9BSK2,Q9NZJ7,Q9H2D1,Q9H936,O43808,Q9UBX3,Q6NUK1,Q9Y619,Q70HW3,P12235,P12236
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
192,33,166,8,296,390,104,82,52,53,345,314
1504,390,880,653,345,314,895,849,736,82,53,33,8,296,561,166,104,464,52,192
-0.14750568765470307,1.0181828688945016,0.3283109386072143,0.5964286373641703,1.1448616242246488,1.2577726487807976,0.31523626177182246,0.36736263752585335,0.49570894697737444,2.351544747161577,2.6086908370116504,2.933230716402563,3.4977473541425774,1.3134519523684933,0.7199845468995671,1.813485136764922,2.199742892007449,0.8887920767692477,2.617683785993935,1.6791960809837663
3,040
Intrinsic component of mitochondrial inner membrane
23
34
3.338279
0.000843
O60830,Q99595,Q9H4I9,Q9Y2R0,Q53H12,Q16891,Q13505,O75431,O43819,Q9HC21,Q6P4A7,Q9Y6N1,O14925,P17152,Q5XKP0,O75880,Q9UG56,Q9H3K2,Q9Y512,Q9BUR5,Q8N8Q8,Q15070,Q9NX63
Localization
GO Cellular component
msigdb_gocc
5,6,16,17,548,672,39,169,428,561,311,594,202,460,212,595,223,231,498,116,248,120,633
202,428,5,169,595,1046,460,2435,2138,849,39,120,974,672,548,212,311,1126,248,1358,6,116,231,16,1548,1401,561,689,633,223,17,1068,498,594
1.6372812858760162,0.9479503532206887,3.5833547818711566,1.7930143140179442,0.6708680977120229,0.18287360405382397,0.8887920767692477,-0.6966810077118192,-0.4977273208231059,0.36736263752585335,2.7598629433409028,2.0932019556415513,0.24942576442222106,0.57140782105902,0.7443925370224047,1.5950791374165418,1.2689492993639755,0.11556131040259485,1.477505845798672,-0.04920595720837689,3.575618702542787,2.1127087039343455,1.5312276267961478,3.2175824750230393,-0.1616845798336536,-0.07712328202431389,0.7199845468995671,0.5588579410317828,0.6337642954290207,1.5632363492107093,3.176547547397983,0.16947255944840645,0.8290467604251529,0.6831850488258874
3,040
Endoplasmic reticulum golgi intermediate compartment membrane
18
29
3.309773
0.000934
O15260,O15155,Q9Y282,O14653,P24390,P53634,Q8N511,P51572,Q96GC9,P56962,Q03518,Q15363,Q10472,Q96RQ1,Q9Y3B3,Q13190,O95070,P49755
Localization
GO Cellular component
msigdb_gocc
128,321,65,481,10,524,142,391,175,305,404,19,210,339,87,217,118,547
481,321,128,796,1170,118,10,2485,817,547,391,524,305,724,404,1209,210,1004,217,19,1123,142,175,339,559,832,65,929,87
0.8530161446660425,1.2241190154546975,2.034312887492732,0.43188252856076326,0.0748011186548802,2.0932019556415513,3.474202711443219,-0.7279101605274243,0.4190345519703002,0.7443925370224047,1.0181828688945016,0.7687015520901122,1.2912412532455868,0.5083924363167223,1.0065340223336994,0.047469694504802575,1.6056568490181453,0.22289491850198123,1.5844831960754728,3.1269576003524127,0.11556131040259485,1.964897593179475,1.7724755011768645,1.1676123346776395,0.7199845468995671,0.39325486209580973,2.4814280266167166,0.2889999091039554,2.2950487183120347
3,040
Sphingolipid metabolism
15
25
3.308863
0.000937
P16278,O95470,Q9NZJ7,Q13510,P06865,Q9NXE4,O15269,Q06136,P17900,Q96G23,P06280,P10619,P07602,P51648,P04062
Processes and pathways
Reactome Pathways
msigdb_reactome
99,261,166,38,101,496,245,461,111,147,313,153,155,94,63
1473,505,245,903,612,1619,261,63,313,101,155,1204,153,99,111,2552,848,94,461,38,147,1879,496,166,1947
-0.1333611726485954,0.8049813983798076,1.477505845798672,0.3021326319906221,0.6461578360344038,-0.21874759683495115,1.4124116297329234,2.4814280266167166,1.2577726487807976,2.218920411804227,1.8946982228718794,0.047469694504802575,1.904775442700116,2.228487185887663,2.151540289571206,-0.7908840017599092,0.36736263752585335,2.2571001484359003,0.8887920767692477,2.7774136025275533,1.944921479987834,-0.36390379043786164,0.8410433975918085,1.813485136764922,-0.3933759714785898
3,040
Intrinsic component of golgi membrane
10
12
3.291161
0.000998
Q9Y5U9,Q9Y282,O15155,Q6ZRP7,L0R6Q1,P98194,O95070,O15258,O43505,Q8TB61
Localization
GO Cellular component
msigdb_gocc
356,65,321,160,140,364,118,379,348,157
140,321,379,348,118,364,1175,160,157,417,65,356
1.964897593179475,1.2241190154546975,1.0414134334695793,1.1220252798248234,2.0932019556415513,1.0760928564449042,0.0748011186548802,1.8440649572883736,1.8643679316323016,0.9831687287835464,2.4814280266167166,1.1105747746411097
3,040
Organic anion transport
30
43
3.283301
0.001026
Q9H2D1,O43808,P05141,P07602,Q8TB61,Q99808,Q8TDW0,Q9NZJ7,Q15041,Q9H936,Q9HC21,O75915,Q9Y619,P28288,P12236,Q08722,Q8N697,Q9UJS0,Q6NUK1,Q9NP80,P12235,Q14728,O60831,Q02978,P08195,Q9UBX3,P14174,O00400,Q7L0J3,P53985
Processes and pathways
GO Biological process
msigdb_gobp
8,390,653,155,157,286,550,166,425,296,561,681,52,183,314,323,588,464,82,214,345,218,224,736,732,104,106,109,370,628
109,390,224,880,681,1046,2229,653,1269,155,732,750,345,314,106,2104,183,1189,895,628,896,736,323,218,425,1541,1542,82,2443,370,588,157,550,286,8,296,1548,561,214,166,104,464,52
2.170865945299008,1.0181828688945016,1.5525853052037832,0.3283109386072143,0.5588579410317828,0.18287360405382397,-0.5582145656983658,0.5964286373641703,0.006232385460175731,1.8946982228718794,0.49570894697737444,0.48299836247200467,1.1448616242246488,1.2577726487807976,2.1901320481563595,-0.4827041033346785,1.7311919224355028,0.061151309647997754,0.31523626177182246,0.6337642954290207,0.31523626177182246,0.49570894697737444,1.2241190154546975,1.5844831960754728,0.9597126649630634,-0.1616845798336536,-0.1616845798336536,2.351544747161577,-0.6966810077118192,1.0645551154147626,0.6831850488258874,1.8643679316323016,0.7443925370224047,1.3466170528239039,3.4977473541425774,1.3134519523684933,-0.1616845798336536,0.7199845468995671,1.5950791374165418,1.813485136764922,2.199742892007449,0.8887920767692477,2.617683785993935
3,040
Lytic vacuole organization
9
21
3.274926
0.001057
Q9HC07,P54802,O14773,Q8N511,P50897,O75503,Q14108,Q9P253,P04062
Processes and pathways
GO Biological process
msigdb_gobp
97,167,330,142,15,148,124,253,63
1951,330,148,1572,63,1204,376,490,800,15,1153,167,1208,124,2081,1730,142,1606,1686,97,253
-0.40816850621130574,1.2015793591735133,1.9349092822529808,-0.19014622799961578,2.4814280266167166,0.047469694504802575,1.0529953384136446,0.8410433975918085,0.43188252856076326,3.2339235068205605,0.08841928230327178,1.803258193474141,0.047469694504802575,2.0834256614858373,-0.46771987659621755,-0.2763755385948963,1.964897593179475,-0.20442935390032577,-0.24749019058283162,2.247577005884701,1.4558845889071608
3,040
Intrinsic component of mitochondrial membrane
32
51
3.270693
0.001073
O95140,O60830,Q15388,Q99595,Q9BWH2,Q9H4I9,Q9GZY8,Q9BPX6,Q9Y2R0,Q53H12,Q16891,Q13505,O75431,O43819,P57105,Q9HC21,Q6P4A7,Q9BUB7,Q9Y6N1,O14925,P17152,Q5XKP0,P12235,O75880,Q9UG56,O96008,Q9H3K2,Q9Y512,Q9BUR5,Q8N8Q8,Q15070,Q9NX63
Localization
GO Cellular component
msigdb_gocc
636,5,394,6,263,16,530,659,17,548,672,39,169,428,46,561,311,450,594,202,460,212,345,595,223,601,231,498,116,248,120,633
202,428,5,169,595,967,636,1046,601,345,460,2435,2138,862,46,849,39,120,394,974,672,548,212,311,1126,1007,841,1024,248,1358,757,6,659,450,116,263,530,231,16,1548,1401,561,3017,689,633,223,721,17,1068,498,594
1.6372812858760162,0.9479503532206887,3.5833547818711566,1.7930143140179442,0.6708680977120229,0.24942576442222106,0.6213449936127172,0.18287360405382397,0.6585257316553426,1.1448616242246488,0.8887920767692477,-0.6966810077118192,-0.4977273208231059,0.3543739888991153,2.6713750460920487,0.36736263752585335,2.7598629433409028,2.0932019556415513,1.0181828688945016,0.24942576442222106,0.57140782105902,0.7443925370224047,1.5950791374165418,1.2689492993639755,0.11556131040259485,0.22289491850198123,0.3803228835675519,0.2095846341582732,1.477505845798672,-0.04920595720837689,0.48299836247200467,3.575618702542787,0.5964286373641703,0.9125251267176329,2.1127087039343455,1.4124116297329234,0.7687015520901122,1.5312276267961478,3.2175824750230393,-0.1616845798336536,-0.07712328202431389,0.7199845468995671,-2.412780764474814,0.5588579410317828,0.6337642954290207,1.5632363492107093,0.5210489561099639,3.176547547397983,0.16947255944840645,0.8290467604251529,0.6831850488258874
3,040
Anion transmembrane transport
27
38
3.266675
0.001088
Q9H2D1,O43808,P05141,Q8TB61,Q8TDW0,Q15041,Q9H936,Q9HC21,O75915,Q9Y619,P12236,Q8N697,Q9Y277,Q9UJS0,O43826,P51790,P12235,Q14728,P21796,O60831,Q02978,P08195,Q9UBX3,P51798,Q9UHG3,P53985,P45880
Processes and pathways
GO Biological process
msigdb_gobp
8,390,653,157,550,425,296,561,681,52,314,588,199,464,332,596,345,218,96,224,736,732,104,754,121,628,123
390,332,224,880,681,1046,653,1269,749,732,345,314,96,1189,123,596,754,895,628,896,849,736,218,425,1542,588,157,550,8,296,1548,561,104,121,464,199,1891,52
1.0181828688945016,1.1902781082588905,1.5525853052037832,0.3283109386072143,0.5588579410317828,0.18287360405382397,0.5964286373641703,0.006232385460175731,0.48299836247200467,0.49570894697737444,1.1448616242246488,1.2577726487807976,2.247577005884701,0.061151309647997754,2.0834256614858373,0.6708680977120229,0.48299836247200467,0.31523626177182246,0.6337642954290207,0.31523626177182246,0.36736263752585335,0.49570894697737444,1.5844831960754728,0.9597126649630634,-0.1616845798336536,0.6831850488258874,1.8643679316323016,0.7443925370224047,3.4977473541425774,1.3134519523684933,-0.1616845798336536,0.7199845468995671,2.199742892007449,2.0932019556415513,0.8887920767692477,1.6582743358244223,-0.36390379043786164,2.617683785993935
3,040
Membrane lipid metabolic process
23
39
3.23226
0.001228
O95470,P50897,Q96G23,O43464,P07602,Q53H12,Q9NZJ7,Q13510,Q5H8A4,Q99805,Q9P035,P06280,P04062,Q06136,Q99735,P16278,P06865,Q9NXE4,P17900,Q92643,Q9H2C2,O15121,O15269
Processes and pathways
GO Biological process
msigdb_gobp
261,15,147,408,155,548,166,38,295,426,173,313,63,461,609,99,101,496,111,371,372,505,245
505,245,903,669,408,1745,261,63,827,313,101,155,1204,99,111,2552,848,1646,15,1322,461,38,548,295,925,772,371,888,147,619,609,426,372,1145,496,1165,166,173,1947
0.8049813983798076,1.477505845798672,0.3021326319906221,0.57140782105902,0.9948626739598494,-0.29087223037784743,1.4124116297329234,2.4814280266167166,0.39325486209580973,1.2577726487807976,2.218920411804227,1.8946982228718794,0.047469694504802575,2.228487185887663,2.151540289571206,-0.7908840017599092,0.36736263752585335,-0.2331011456054219,3.2339235068205605,-0.021421189614910855,0.8887920767692477,2.7774136025275533,0.7443925370224047,1.3134519523684933,0.2889999091039554,0.4702605562765458,1.0645551154147626,0.3283109386072143,1.944921479987834,0.6461578360344038,0.6585257316553426,0.9597126649630634,1.0645551154147626,0.10200596012172755,0.8410433975918085,0.08841928230327178,1.813485136764922,1.782753437123811,-0.3933759714785898
3,040
Glycosaminoglycan metabolism
10
16
3.221118
0.001277
P16278,P15586,P06865,P54802,P08236,O43505,Q7LGA3,Q9NRB3,Q8NCH0,Q8TB61
Processes and pathways
Reactome Pathways
msigdb_reactome
99,196,101,167,211,348,88,417,28,157
1864,348,1083,101,1204,211,624,196,99,167,88,28,157,493,417,1737
-0.36390379043786164,1.1220252798248234,0.1425786554172647,2.218920411804227,0.047469694504802575,1.5950791374165418,0.6337642954290207,1.6582743358244223,2.228487185887663,1.803258193474141,2.2855830809653983,3.0350360441668323,1.8643679316323016,0.8410433975918085,0.9831687287835464,-0.2763755385948963
3,040
Ion transmembrane transport
65
147
3.21691
0.001296
Q9UDW1,Q9HD47,P06576,Q96HE7,Q9H2D1,O43808,Q8N4V1,Q9H4I9,Q9BPX6,P05141,P16615,Q9HD20,P13073,Q8TB61,Q8TDW0,P00846,Q15041,Q9H936,Q96GC9,Q9HC21,O95202,O75915,Q9Y619,Q70HW3,Q9C0H2,Q6P4A7,P05023,Q6PML9,P36543,P12236,Q8IYU8,P24539,Q8N697,Q9Y277,O14548,P05067,Q13423,P56134,Q9UJS0,O75844,O43826,P51790,Q9UHG3,Q14728,O75964,P12235,P27105,Q7KZN9,P21796,Q9HC07,O60831,Q02978,Q9H0U3,P08195,Q9UBX3,P00403,O95747,O00400,P51798,Q8NEW0,P98194,P46939,Q96PU5,P53985,P45880
Processes and pathways
GO Biological process
msigdb_gobp
2,259,387,649,8,390,143,16,659,653,274,150,398,157,550,34,425,296,175,561,50,681,52,53,54,311,563,312,564,314,435,322,588,199,702,73,204,454,464,77,332,596,121,218,90,345,221,222,96,97,224,736,487,732,104,731,234,109,754,492,364,753,632,628,123
2757,109,948,702,1169,1504,390,332,821,2100,224,811,2630,1030,1976,1297,880,77,681,1032,90,50,1046,234,731,34,563,73,653,1269,387,1893,2823,1844,749,732,1694,871,765,2034,1348,345,314,398,274,2759,935,861,1644,2433,3006,96,322,1979,221,2417,2838,1622,1225,2839,1187,564,2434,1189,2372,123,753,1320,893,596,754,895,628,1102,896,454,1001,1411,1020,1118,919,1822,364,849,1302,736,1077,1337,2957,204,1679,1901,218,1873,425,2165,1542,311,312,53,222,911,435,143,588,863,1358,492,157,550,1053,175,649,632,2975,1111,1830,659,1230,1164,54,487,1860,8,1466,16,296,1548,97,561,150,259,820,104,2,1737,121,1712,464,1221,795,199,1167,1891,1068,52,1690
-1.0004827835760666,2.170865945299008,0.2626466181221558,0.5336786310815371,0.0748011186548802,-0.14750568765470307,1.0181828688945016,1.1902781082588905,0.4061587071946509,-0.4827041033346785,1.5525853052037832,0.4190345519703002,-0.854559141460524,0.19624424562674062,-0.4229989506921864,-0.007578087459911156,0.3283109386072143,2.370264417454816,0.5588579410317828,0.19624424562674062,2.276103138392118,2.635631465461991,0.18287360405382397,1.509795357420363,0.49570894697737444,2.9075240878120137,0.7077431607617762,2.4168212862539087,0.5964286373641703,0.006232385460175731,1.0298093080175974,-0.3786211358393844,-1.0998893428363394,-0.3492237281963389,0.48299836247200467,0.49570894697737444,-0.26191492372509495,0.3413568016183609,0.4702605562765458,-0.45277442063761514,-0.04920595720837689,1.1448616242246488,1.2577726487807976,1.0065340223336994,1.3686274111665022,-1.0004827835760666,0.2758379519036087,0.3543739888991153,-0.2331011456054219,-0.6966810077118192,-1.9267497642243225,2.247577005884701,1.2241190154546975,-0.4229989506921864,1.5632363492107093,-0.6811299828485751,-1.1334162316136511,-0.21874759683495115,0.033756111184921174,-1.1334162316136511,0.061151309647997754,0.7077431607617762,-0.6966810077118192,0.061151309647997754,-0.6501537901627932,2.0834256614858373,0.48299836247200467,-0.021421189614910855,0.31523626177182246,0.6708680977120229,0.48299836247200467,0.31523626177182246,0.6337642954290207,0.1290854902149427,0.31523626177182246,0.9006702914867534,0.22289491850198123,-0.09113208586471662,0.2095846341582732,0.11556131040259485,0.2889999091039554,-0.33458074379489317,1.0760928564449042,0.36736263752585335,-0.007578087459911156,0.49570894697737444,0.15604096067010367,-0.03529708956303091,-1.4267397471439798,1.6372812858760162,-0.24749019058283162,-0.3786211358393844,1.5844831960754728,-0.36390379043786164,0.9597126649630634,-0.5127897509611888,-0.1616845798336536,1.2689492993639755,1.2689492993639755,2.6086908370116504,1.5632363492107093,0.3021326319906221,0.9361650584683445,1.954917564819329,0.6831850488258874,0.3543739888991153,-0.04920595720837689,0.8410433975918085,1.8643679316323016,0.7443925370224047,0.18287360405382397,1.7724755011768645,0.6088998135451131,0.6337642954290207,-1.5521212839747416,0.1290854902149427,-0.33458074379489317,0.5964286373641703,0.033756111184921174,0.08841928230327178,2.6086908370116504,0.8530161446660425,-0.3492237281963389,3.4977473541425774,-0.11925085360259,3.2175824750230393,1.3134519523684933,-0.1616845798336536,2.247577005884701,0.7199845468995671,1.9248809148764459,1.4233088612462526,0.4190345519703002,2.199742892007449,3.7813362177920875,-0.2763755385948963,2.0932019556415513,-0.26191492372509495,0.8887920767692477,0.047469694504802575,0.44470276814533355,1.6582743358244223,0.08841928230327178,-0.36390379043786164,0.16947255944840645,2.617683785993935,-0.24749019058283162
3,040
SLC superfamily of solute carriers
23
44
3.201741
0.001366
Q9H2D1,O43808,Q8TB61,Q99808,Q9BSK2,Q9NZJ7,Q9H936,O95202,Q9Y619,Q70HW3,Q6PML9,P12236,Q9Y6C9,Q9UJS0,O43826,Q6NUK1,Q9H2V7,P12235,Q9HC07,Q9H0U3,Q9UBX3,O00400,Q7L0J3
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
8,390,157,286,33,166,296,50,52,53,312,314,192,464,332,82,213,345,97,487,104,109,370
109,1504,390,332,880,50,1046,653,732,750,345,314,1189,895,628,896,849,736,1542,3007,1158,82,2443,312,53,370,1462,588,492,157,286,33,487,8,213,296,1548,97,561,166,104,464,52,192
2.170865945299008,-0.14750568765470307,1.0181828688945016,1.1902781082588905,0.3283109386072143,2.635631465461991,0.18287360405382397,0.5964286373641703,0.49570894697737444,0.48299836247200467,1.1448616242246488,1.2577726487807976,0.061151309647997754,0.31523626177182246,0.6337642954290207,0.31523626177182246,0.36736263752585335,0.49570894697737444,-0.1616845798336536,-1.9267497642243225,0.08841928230327178,2.351544747161577,-0.6966810077118192,1.2689492993639755,2.6086908370116504,1.0645551154147626,-0.11925085360259,0.6831850488258874,0.8410433975918085,1.8643679316323016,1.3466170528239039,2.933230716402563,0.8530161446660425,3.4977473541425774,1.5950791374165418,1.3134519523684933,-0.1616845798336536,2.247577005884701,0.7199845468995671,1.813485136764922,2.199742892007449,0.8887920767692477,2.617683785993935,1.6791960809837663
3,040
Organelle inner membrane
101
241
3.192171
0.001412
Q96IX5,Q9UDW1,O60830,Q99595,Q9H2D1,Q7Z7H8,Q9H4I9,Q9Y2R0,Q9UDX5,O95831,Q9NPL8,P20700,P62072,O43676,Q9BSK2,Q53H12,P00846,O96000,Q13505,Q9H061,P51970,Q9HC21,O95202,P50402,Q70HW3,Q9Y619,Q96CU9,Q9H1E5,Q9Y584,Q3ZCQ8,Q69YU5,P22695,Q9Y6N1,Q8NI60,O75844,Q6NUK1,O14949,Q5T9A4,Q7Z7F7,O75880,O75964,P14406,O96008,Q9H2W6,Q9UBX3,Q9BUR5,Q15070,Q10713,Q86Y39,Q567V2,Q8IXM6,O75431,P53701,Q96E52,P03886,Q9Y6C9,Q13423,P22830,O14925,Q9H2V7,Q5XKP0,Q14728,Q9UG56,Q7KZN9,Q9H3K2,Q6DKK2,O60220,Q8N8Q8,Q9Y5J9,O75438,O60313,Q9H936,Q14739,Q6P4A7,P12236,P24539,P56378,O43615,P12235,Q8NBN7,Q9NVI7,P06576,P13073,Q5SNT2,O75306,O43819,Q8IYU8,Q9BUB7,Q9P0J0,P23786,P56134,Q5HYK3,Q9UJS0,O95168,P17152,P36551,O94901,Q03252,Q9Y512,P82933,P18031
Localization
GO Cellular component
msigdb_gocc
518,2,5,6,8,528,16,17,22,23,540,534,29,32,33,548,34,545,39,42,556,561,50,565,53,52,55,57,60,566,62,67,594,589,77,82,84,599,86,595,90,91,601,621,104,116,120,131,145,159,161,169,178,179,187,192,204,203,202,213,212,218,223,222,231,232,233,248,264,290,292,296,307,311,314,322,326,340,345,352,367,387,398,410,413,428,435,450,451,447,454,455,464,459,460,468,489,491,498,497,499
948,702,202,84,340,32,1504,428,233,292,1842,5,811,1030,413,169,290,1297,1171,1203,1775,880,77,595,1032,90,1955,489,459,50,1070,1046,951,23,545,601,731,34,187,2344,653,387,2901,1694,1747,1815,2034,2805,345,314,2806,398,91,2203,460,2456,499,2717,861,534,1318,1351,67,203,1672,447,322,1979,2985,2719,1225,1319,1534,1187,468,2435,1226,2036,1135,1334,1320,2459,2158,2721,2138,565,1800,556,2283,895,178,1752,2074,454,326,1001,2349,29,824,1899,1275,1061,2948,1105,2113,883,2304,497,849,736,491,131,1455,1852,1564,204,39,2239,218,307,120,974,791,2694,1279,672,566,548,159,455,1728,410,599,212,62,232,82,1326,311,2790,1126,2170,53,222,1395,86,528,145,161,435,842,248,2833,352,2333,1358,589,758,1416,1376,1519,55,179,1360,2407,518,776,6,1111,2964,659,1634,1144,1256,33,620,1788,450,116,777,676,1217,1989,2223,1420,42,57,8,213,621,231,16,1440,296,1548,1664,1401,1260,561,1441,1525,540,3017,2176,689,367,1550,902,1330,633,1769,1290,1232,451,104,2,22,223,914,464,1221,1792,2641,1739,17,1499,1714,1950,1379,1992,977,1890,1068,498,60,264,2909,52,192,2430,594
0.2626466181221558,0.5336786310815371,1.6372812858760162,2.3139372650206984,1.1562476399214794,2.9588343365432377,-0.14750568765470307,0.9479503532206887,1.509795357420363,1.3245270326423748,-0.3492237281963389,3.5833547818711566,0.4190345519703002,0.19624424562674062,0.9831687287835464,1.7930143140179442,1.3355820397418836,-0.007578087459911156,0.0748011186548802,0.047469694504802575,-0.30540519590093435,0.3283109386072143,2.370264417454816,0.6708680977120229,0.19624424562674062,2.276103138392118,-0.40816850621130574,0.8410433975918085,0.8887920767692477,2.635631465461991,0.15604096067010367,0.18287360405382397,0.2626466181221558,3.085338247748161,0.7443925370224047,0.6585257316553426,0.49570894697737444,2.9075240878120137,1.6896303788651301,-0.634728130674405,0.5964286373641703,1.0298093080175974,-1.2523520160372588,-0.26191492372509495,-0.29087223037784743,-0.33458074379489317,-0.45277442063761514,-1.0665598073816422,1.1448616242246488,1.2577726487807976,-1.0665598073816422,1.0065340223336994,2.276103138392118,-0.5430331465710542,0.8887920767692477,-0.712274316441883,0.8170261289828668,-0.9514247127867999,0.3543739888991153,0.7565593617275889,-0.021421189614910855,-0.04920595720837689,2.453820478435673,1.6372812858760162,-0.24749019058283162,0.9125251267176329,1.2241190154546975,-0.4229989506921864,-1.680384786537059,-0.9514247127867999,0.033756111184921174,-0.021421189614910855,-0.1616845798336536,0.061151309647997754,0.8768903817981308,-0.6966810077118192,0.033756111184921174,-0.45277442063761514,0.10200596012172755,-0.03529708956303091,-0.021421189614910855,-0.712274316441883,-0.5127897509611888,-0.9514247127867999,-0.4977273208231059,0.7077431607617762,-0.31997463365124035,0.7199845468995671,-0.5886979958768187,0.31523626177182246,1.7621804442172937,-0.29087223037784743,-0.46771987659621755,0.9006702914867534,1.2128596333356767,0.22289491850198123,-0.634728130674405,3.0266138343517364,0.4061587071946509,-0.3786211358393844,0.006232385460175731,0.16947255944840645,-1.3914262873845131,0.1290854902149427,-0.4827041033346785,0.3283109386072143,-0.604000472797998,0.8290467604251529,0.36736263752585335,0.49570894697737444,0.8410433975918085,2.0145588418698184,-0.11925085360259,-0.3492237281963389,-0.1758980318826104,1.6372812858760162,2.7598629433409028,-0.5582145656983658,1.5844831960754728,1.2912412532455868,2.0932019556415513,0.24942576442222106,0.44470276814533355,-0.9189528352734494,0.006232385460175731,0.57140782105902,0.7077431607617762,0.7443925370224047,1.8440649572883736,0.9006702914867534,-0.2763755385948963,0.9948626739598494,0.6708680977120229,1.5950791374165418,2.4906037531718463,1.5205208514694646,2.351544747161577,-0.021421189614910855,1.2689492993639755,-1.0334251097631109,0.11556131040259485,-0.5127897509611888,2.6086908370116504,1.5632363492107093,-0.07712328202431389,2.2950487183120347,0.7687015520901122,1.944921479987834,1.833888458243914,0.9361650584683445,0.3803228835675519,1.477505845798672,-1.1166279588884744,1.1105747746411097,-0.6193437716665054,-0.04920595720837689,0.6831850488258874,0.48299836247200467,-0.09113208586471662,-0.06314796381553464,-0.14750568765470307,2.5996850958566853,1.751868203937735,-0.04920595720837689,-0.6656209926480597,0.7808192166024813,0.4702605562765458,3.575618702542787,0.1290854902149427,-1.4801308573975738,0.5964286373641703,-0.21874759683495115,0.10200596012172755,0.020010396372018485,2.933230716402563,0.6461578360344038,-0.30540519590093435,0.9125251267176329,2.1127087039343455,0.4702605562765458,0.57140782105902,0.047469694504802575,-0.4229989506921864,-0.5430331465710542,-0.09113208586471662,2.73344577811532,2.5635334118063744,3.4977473541425774,1.5950791374165418,0.6461578360344038,1.5312276267961478,3.2175824750230393,-0.10517455077210873,1.3134519523684933,-0.1616845798336536,-0.2331011456054219,-0.07712328202431389,0.020010396372018485,0.7199845468995671,-0.10517455077210873,-0.14750568765470307,0.7565593617275889,-2.412780764474814,-0.5127897509611888,0.5588579410317828,1.0760928564449042,-0.1616845798336536,0.31523626177182246,-0.021421189614910855,0.6337642954290207,-0.29087223037784743,0.006232385460175731,0.033756111184921174,0.9125251267176329,2.199742892007449,3.7813362177920875,3.118655281310429,1.5632363492107093,0.3021326319906221,0.8887920767692477,0.047469694504802575,-0.30540519590093435,-0.854559141460524,-0.2763755385948963,3.176547547397983,-0.1333611726485954,-0.26191492372509495,-0.3933759714785898,-0.06314796381553464,-0.4229989506921864,0.24942576442222106,-0.36390379043786164,0.16947255944840645,0.8290467604251529,2.4997661556800703,1.4124116297329234,-1.269549423261982,2.617683785993935,1.6791960809837663,-0.6811299828485751,0.6831850488258874
3,040
Alcohol binding
6
18
3.185201
0.001447
P21796,P09455,Q14849,O15118,P45880,Q14108
Functions
GO Molecular function
msigdb_gomf
96,98,43,238,123,124
574,238,1745,2131,1531,269,1844,98,96,1241,1386,645,123,828,124,43,1009,1287
0.6954766988270652,1.4990510731461264,-0.29087223037784743,-0.4977273208231059,-0.1616845798336536,1.3905587313935528,-0.3492237281963389,2.228487185887663,2.247577005884701,0.020010396372018485,-0.07712328202431389,0.6088998135451131,2.0834256614858373,0.39325486209580973,2.0834256614858373,2.706918315651424,0.22289491850198123,0.006232385460175731
3,040
Lysosomal lumen
20
36
3.18244
0.00146
P50897,P10619,P07602,Q9NZJ7,Q13510,P54802,P06280,P04062,P15586,O14773,Q9UMR5,P08236,Q9UM22,Q8NHP8,P16278,P06865,P17900,P38435,Q8IV08,Q14108
Localization
GO Cellular component
msigdb_gocc
15,153,155,166,38,167,313,63,196,330,85,211,219,350,99,101,111,239,117,124
573,778,762,330,612,63,827,313,101,155,1204,2576,211,376,153,490,906,196,99,111,239,3009,546,15,167,828,38,124,117,2194,350,578,831,166,219,85
0.6954766988270652,0.45749540095397245,0.4702605562765458,1.2015793591735133,0.6461578360344038,2.4814280266167166,0.39325486209580973,1.2577726487807976,2.218920411804227,1.8946982228718794,0.047469694504802575,-0.8067363769252331,1.5950791374165418,1.0529953384136446,1.904775442700116,0.8410433975918085,0.3021326319906221,1.6582743358244223,2.228487185887663,2.151540289571206,1.4990510731461264,-2.004819626017603,0.7443925370224047,3.2339235068205605,1.803258193474141,0.39325486209580973,2.7774136025275533,2.0834256614858373,2.10296295242631,-0.5278916176011564,1.1220252798248234,0.6954766988270652,0.39325486209580973,1.813485136764922,1.5844831960754728,2.3139372650206984
3,040
Primary mitochondrial disease
32
93
3.176908
0.001489
Q9NWS8,Q96IX5,Q9Y2R0,Q86Y39,Q9NPL8,O95831,P13073,O43676,Q53H12,P00846,O60313,O75306,O43819,Q70HW3,Q96CU9,Q6P4A7,Q9Y584,P03886,Q9BUB7,Q9P0J0,P22695,Q8NI60,O14949,Q5XKP0,O75880,P12235,Q96RR1,Q7KZN9,Q9UBX3,Q6DKK2,Q99797,P51530
Drugs and Diseases
Protein Atlas Disease involvement
protein_atlas_disease_involvement
522,518,17,145,540,23,398,32,548,34,292,413,428,53,55,311,60,187,450,451,67,589,84,212,595,345,608,222,104,232,495,627
948,84,32,2629,428,292,1842,1030,413,1171,1238,595,1070,23,731,34,187,2479,1694,1747,345,398,2203,2717,861,67,1979,2985,2719,2036,2157,2617,2721,627,2283,2374,1899,2304,1076,767,1279,548,2464,1392,1177,1371,1907,212,232,311,53,222,1461,145,842,1396,674,589,2310,55,650,518,1940,608,495,2365,2174,1256,1230,1788,450,1081,1196,1440,1664,540,522,902,1232,451,2640,104,1792,1739,17,1499,1555,1950,1379,977,1890,60,2430
0.2626466181221558,2.3139372650206984,2.9588343365432377,-0.854559141460524,0.9479503532206887,1.3245270326423748,-0.3492237281963389,0.19624424562674062,0.9831687287835464,0.0748011186548802,0.020010396372018485,0.6708680977120229,0.15604096067010367,3.085338247748161,0.49570894697737444,2.9075240878120137,1.6896303788651301,-0.7279101605274243,-0.26191492372509495,-0.29087223037784743,1.1448616242246488,1.0065340223336994,-0.5430331465710542,-0.9514247127867999,0.3543739888991153,2.453820478435673,-0.4229989506921864,-1.680384786537059,-0.9514247127867999,-0.45277442063761514,-0.5127897509611888,-0.8385736772120257,-0.9514247127867999,0.6337642954290207,-0.5886979958768187,-0.6501537901627932,-0.3786211358393844,-0.604000472797998,0.15604096067010367,0.4702605562765458,0.006232385460175731,0.7443925370224047,-0.712274316441883,-0.07712328202431389,0.0748011186548802,-0.06314796381553464,-0.3786211358393844,1.5950791374165418,1.5205208514694646,1.2689492993639755,2.6086908370116504,1.5632363492107093,-0.11925085360259,1.944921479987834,0.3803228835675519,-0.07712328202431389,0.57140782105902,0.6831850488258874,-0.604000472797998,2.5996850958566853,0.6088998135451131,0.7808192166024813,-0.3933759714785898,0.6585257316553426,0.8410433975918085,-0.634728130674405,-0.5127897509611888,0.020010396372018485,0.033756111184921174,-0.30540519590093435,0.9125251267176329,0.15604096067010367,0.061151309647997754,-0.10517455077210873,-0.2331011456054219,0.7565593617275889,0.7808192166024813,0.31523626177182246,0.033756111184921174,0.9125251267176329,-0.854559141460524,2.199742892007449,-0.30540519590093435,-0.2763755385948963,3.176547547397983,-0.1333611726485954,-0.1616845798336536,-0.3933759714785898,-0.06314796381553464,0.24942576442222106,-0.36390379043786164,2.4997661556800703,-0.6811299828485751
3,040
Glycosphingolipid metabolism
8
14
3.162734
0.001563
P16278,P06865,Q9NZJ7,Q13510,P17900,P10619,P07602,P04062
Processes and pathways
Reactome Pathways
msigdb_reactome
99,101,166,38,111,153,155,63
1473,612,63,313,101,155,1204,153,99,111,38,1879,496,166
-0.1333611726485954,0.6461578360344038,2.4814280266167166,1.2577726487807976,2.218920411804227,1.8946982228718794,0.047469694504802575,1.904775442700116,2.228487185887663,2.151540289571206,2.7774136025275533,-0.36390379043786164,0.8410433975918085,1.813485136764922
3,040
Transmembrane transport
72
202
3.149062
0.001638
Q8WTV0,Q9UDW1,O75381,Q9HD47,O60830,Q99595,P06576,Q9H2D1,Q9NS69,Q15388,O43808,L0R6Q1,Q8N4V1,Q9H4I9,P16615,Q03518,Q9HD20,O95831,P13073,Q9Y5Y5,Q8TB61,Q99808,Q9BSK2,P00846,Q15041,Q9H936,Q96GC9,O95202,Q8IYU8,Q9Y619,Q70HW3,Q9C0H2,P28288,Q6P4A7,Q6PML9,P12236,Q9Y584,P04062,P23786,P24539,P56134,Q9Y277,P05067,Q13423,Q9UJS0,O75844,O14925,Q15629,O43826,Q6NUK1,Q9H2V7,Q99442,O43615,P12235,Q14728,O75964,P27105,Q7KZN9,P21796,Q9HC07,O60831,Q9H0U3,Q9UBX3,Q99797,O95747,Q8NE01,O00400,P98194,P38435,Q7L0J3,Q9UHG3,P45880
Processes and pathways
GO Biological process
msigdb_gobp
255,2,130,259,5,6,387,8,9,394,390,140,143,16,274,404,150,23,398,289,157,286,33,34,425,296,175,50,435,52,53,54,183,311,312,314,60,63,447,322,454,199,73,204,464,77,202,79,332,82,213,342,340,345,218,90,221,222,96,97,224,487,104,495,234,363,109,364,239,370,121,123
140,993,2757,109,948,702,202,340,1169,1504,390,332,821,2100,5,224,811,2630,1030,1976,130,1297,880,77,681,1032,90,967,50,1046,234,23,601,731,34,63,563,73,653,1269,387,1893,2823,1116,1844,749,732,1694,871,765,2034,2805,750,1348,345,314,398,274,2759,935,861,1644,2433,3006,96,447,322,1979,221,2417,183,2838,1622,799,1225,637,2839,1187,564,239,2434,1189,2372,123,753,1320,547,862,823,893,596,754,1101,895,628,1102,896,454,1001,1696,2109,1411,1020,1118,919,1822,364,849,1302,2256,736,404,1077,2377,1337,790,2957,204,1679,1901,218,1873,425,2165,394,79,1542,566,1158,82,2443,311,312,803,53,222,370,911,1462,435,143,588,863,363,1358,492,157,2310,550,255,1053,175,649,632,342,2975,718,6,1111,495,286,1830,659,1230,33,1164,1009,54,487,1860,8,213,1466,16,296,1548,1260,97,561,150,259,3017,9,820,104,2,846,1737,121,1712,464,1221,3018,795,199,1167,1891,1068,60,289,52,1690
1.964897593179475,0.22289491850198123,-1.0004827835760666,2.170865945299008,0.2626466181221558,0.5336786310815371,1.6372812858760162,1.1562476399214794,0.0748011186548802,-0.14750568765470307,1.0181828688945016,1.1902781082588905,0.4061587071946509,-0.4827041033346785,3.5833547818711566,1.5525853052037832,0.4190345519703002,-0.854559141460524,0.19624424562674062,-0.4229989506921864,2.0145588418698184,-0.007578087459911156,0.3283109386072143,2.370264417454816,0.5588579410317828,0.19624424562674062,2.276103138392118,0.24942576442222106,2.635631465461991,0.18287360405382397,1.509795357420363,3.085338247748161,0.6585257316553426,0.49570894697737444,2.9075240878120137,2.4814280266167166,0.7077431607617762,2.4168212862539087,0.5964286373641703,0.006232385460175731,1.0298093080175974,-0.3786211358393844,-1.0998893428363394,0.11556131040259485,-0.3492237281963389,0.48299836247200467,0.49570894697737444,-0.26191492372509495,0.3413568016183609,0.4702605562765458,-0.45277442063761514,-1.0665598073816422,0.48299836247200467,-0.04920595720837689,1.1448616242246488,1.2577726487807976,1.0065340223336994,1.3686274111665022,-1.0004827835760666,0.2758379519036087,0.3543739888991153,-0.2331011456054219,-0.6966810077118192,-1.9267497642243225,2.247577005884701,0.9125251267176329,1.2241190154546975,-0.4229989506921864,1.5632363492107093,-0.6811299828485751,1.7311919224355028,-1.1334162316136511,-0.21874759683495115,0.43188252856076326,0.033756111184921174,0.6213449936127172,-1.1334162316136511,0.061151309647997754,0.7077431607617762,1.4990510731461264,-0.6966810077118192,0.061151309647997754,-0.6501537901627932,2.0834256614858373,0.48299836247200467,-0.021421189614910855,0.7443925370224047,0.3543739888991153,0.4061587071946509,0.31523626177182246,0.6708680977120229,0.48299836247200467,0.1290854902149427,0.31523626177182246,0.6337642954290207,0.1290854902149427,0.31523626177182246,0.9006702914867534,0.22289491850198123,-0.26191492372509495,-0.4827041033346785,-0.09113208586471662,0.2095846341582732,0.11556131040259485,0.2889999091039554,-0.33458074379489317,1.0760928564449042,0.36736263752585335,-0.007578087459911156,-0.5734361048340421,0.49570894697737444,1.0065340223336994,0.15604096067010367,-0.6501537901627932,-0.03529708956303091,0.44470276814533355,-1.4267397471439798,1.6372812858760162,-0.24749019058283162,-0.3786211358393844,1.5844831960754728,-0.36390379043786164,0.9597126649630634,-0.5127897509611888,1.0181828688945016,2.360911550267849,-0.1616845798336536,0.7077431607617762,0.08841928230327178,2.351544747161577,-0.6966810077118192,1.2689492993639755,1.2689492993639755,0.43188252856076326,2.6086908370116504,1.5632363492107093,1.0645551154147626,0.3021326319906221,-0.11925085360259,0.9361650584683445,1.954917564819329,0.6831850488258874,0.3543739888991153,1.0876086528881501,-0.04920595720837689,0.8410433975918085,1.8643679316323016,-0.604000472797998,0.7443925370224047,1.4341867150381478,0.18287360405382397,1.7724755011768645,0.6088998135451131,0.6337642954290207,1.1562476399214794,-1.5521212839747416,0.5210489561099639,3.575618702542787,0.1290854902149427,0.8410433975918085,1.3466170528239039,-0.33458074379489317,0.5964286373641703,0.033756111184921174,2.933230716402563,0.08841928230327178,0.22289491850198123,2.6086908370116504,0.8530161446660425,-0.3492237281963389,3.4977473541425774,1.5950791374165418,-0.11925085360259,3.2175824750230393,1.3134519523684933,-0.1616845798336536,0.020010396372018485,2.247577005884701,0.7199845468995671,1.9248809148764459,1.4233088612462526,-2.412780764474814,3.4820604215174513,0.4190345519703002,2.199742892007449,3.7813362177920875,0.3803228835675519,-0.2763755385948963,2.0932019556415513,-0.26191492372509495,0.8887920767692477,0.047469694504802575,-2.412780764474814,0.44470276814533355,1.6582743358244223,0.08841928230327178,-0.36390379043786164,0.16947255944840645,2.4997661556800703,1.3466170528239039,2.617683785993935,-0.24749019058283162
3,040
Transporter
78
192
3.131925
0.001737
Q9C0E2,Q9H2D1,Q8NFH4,P24390,Q9BQE5,Q15363,O95249,P49755,Q9BSK2,P00846,O43760,Q9BVK6,Q9HC21,O95202,O43752,Q9Y619,Q70HW3,P05023,Q9Y584,Q9P2W9,Q8N697,Q6NUK1,Q9Y3B3,Q9HC07,Q8TEX9,Q9UBX3,Q9Y487,O00400,P17900,Q15070,O43731,Q9HD45,Q93050,Q8TB61,Q9NZJ7,P28288,O00560,Q9Y6C9,Q9H2V7,Q13190,Q9P253,Q9H6H4,P16615,Q99808,Q9H936,Q9UEU0,P54105,P56962,Q6PML9,P12236,O15155,P24539,Q6NUK4,O43826,Q00765,P12235,O60749,Q8N1F7,Q13277,P98194,Q7L0J3,P06576,Q15388,O43808,P51572,Q03518,Q92973,Q99805,Q99567,P56134,Q9UJS0,O15400,P53680,O95721,O14653,Q86Y82,Q9H0U3,Q8NEW0
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
520,8,516,10,13,19,523,547,33,34,45,559,561,50,51,52,53,563,60,69,588,82,87,97,100,104,105,109,111,120,127,137,146,157,166,183,190,192,213,217,253,256,274,286,296,297,299,305,312,314,321,322,324,332,336,345,344,346,365,364,370,387,394,390,391,404,411,426,442,454,464,466,478,476,481,484,487,492
2571,993,1951,109,1774,1863,190,787,2875,481,321,466,127,51,45,1504,390,332,704,2596,1149,344,1669,811,2631,880,1032,2227,50,523,1619,1843,1046,476,601,34,563,653,387,749,732,953,1621,750,1317,345,314,274,111,935,1644,2433,10,322,1979,183,1645,1624,1187,1017,2434,1189,2001,2252,817,547,823,391,1018,894,1511,895,2420,1575,478,628,1932,299,1102,1454,896,454,1001,305,937,1411,1020,2460,2110,364,849,2604,336,736,404,1209,2161,782,1004,217,365,1629,1756,2163,1854,120,2307,2165,19,394,1542,3007,1158,82,324,2443,312,53,370,1080,484,1462,346,588,863,492,516,2834,157,818,100,1162,1659,591,607,411,146,1052,1606,1829,1053,1686,2653,718,442,426,286,13,2930,33,559,520,487,2447,8,213,1663,256,296,1548,97,561,137,3017,2247,1442,166,1810,1947,253,69,2932,1688,104,297,1469,1712,976,464,1791,1055,1528,2654,929,87,105,60,1292,2966,52,1668,192
-0.8067363769252331,0.22289491850198123,-0.40816850621130574,2.170865945299008,-0.30540519590093435,-0.36390379043786164,1.6791960809837663,0.44470276814533355,-1.1840822292813866,0.8530161446660425,1.2241190154546975,0.8768903817981308,2.0441664596066604,2.626663982355961,2.6891715667114098,-0.14750568765470307,1.0181828688945016,1.1902781082588905,0.5336786310815371,-0.8226328459755452,0.08841928230327178,1.1448616242246488,-0.24749019058283162,0.4190345519703002,-0.854559141460524,0.3283109386072143,0.19624424562674062,-0.5582145656983658,2.635631465461991,0.7687015520901122,-0.21874759683495115,-0.3492237281963389,0.18287360405382397,0.864965105135409,0.6585257316553426,2.9075240878120137,0.7077431607617762,0.5964286373641703,1.0298093080175974,0.48299836247200467,0.49570894697737444,0.2626466181221558,-0.21874759683495115,0.48299836247200467,-0.021421189614910855,1.1448616242246488,1.2577726487807976,1.3686274111665022,2.151540289571206,0.2758379519036087,-0.2331011456054219,-0.6966810077118192,3.474202711443219,1.2241190154546975,-0.4229989506921864,1.7311919224355028,-0.2331011456054219,-0.21874759683495115,0.061151309647997754,0.2095846341582732,-0.6966810077118192,0.061151309647997754,-0.43786751739574514,-0.5734361048340421,0.4190345519703002,0.7443925370224047,0.4061587071946509,1.0181828688945016,0.2095846341582732,0.31523626177182246,-0.14750568765470307,0.31523626177182246,-0.6811299828485751,-0.19014622799961578,0.864965105135409,0.6337642954290207,-0.3933759714785898,1.302356719279247,0.1290854902149427,-0.11925085360259,0.31523626177182246,0.9006702914867534,0.22289491850198123,1.2912412532455868,0.2758379519036087,-0.09113208586471662,0.2095846341582732,-0.712274316441883,-0.4827041033346785,1.0760928564449042,0.36736263752585335,-0.8226328459755452,1.1789557953519179,0.49570894697737444,1.0065340223336994,0.047469694504802575,-0.5127897509611888,0.45749540095397245,0.22289491850198123,1.5844831960754728,1.0760928564449042,-0.21874759683495115,-0.29087223037784743,-0.5127897509611888,-0.3492237281963389,2.0932019556415513,-0.604000472797998,-0.5127897509611888,3.1269576003524127,1.0181828688945016,-0.1616845798336536,-1.9267497642243225,0.08841928230327178,2.351544747161577,1.2241190154546975,-0.6966810077118192,1.2689492993639755,2.6086908370116504,1.0645551154147626,0.15604096067010367,0.8530161446660425,-0.11925085360259,1.1334542001794992,0.6831850488258874,0.3543739888991153,0.8410433975918085,0.7808192166024813,-1.1166279588884744,1.8643679316323016,0.4190345519703002,2.228487185887663,0.08841928230327178,-0.2331011456054219,0.6831850488258874,0.6585257316553426,0.9948626739598494,1.944921479987834,0.18287360405382397,-0.20442935390032577,-0.33458074379489317,0.18287360405382397,-0.24749019058283162,-0.870589512103763,0.5210489561099639,0.9243566825638713,0.9597126649630634,1.3466170528239039,3.3069498983425705,-1.338869380346214,2.933230716402563,0.7199845468995671,0.7808192166024813,0.8530161446660425,-0.6966810077118192,3.4977473541425774,1.5950791374165418,-0.2331011456054219,1.4341867150381478,1.3134519523684933,-0.1616845798336536,2.247577005884701,0.7199845468995671,1.9947418992044237,-2.412780764474814,-0.5582145656983658,-0.10517455077210873,1.813485136764922,-0.31997463365124035,-0.3933759714785898,1.4558845889071608,2.4445910304154994,-1.338869380346214,-0.24749019058283162,2.199742892007449,1.3134519523684933,-0.11925085360259,-0.26191492372509495,0.24942576442222106,0.8887920767692477,-0.30540519590093435,0.18287360405382397,-0.14750568765470307,-0.870589512103763,0.2889999091039554,2.2950487183120347,2.199742892007449,2.4997661556800703,0.006232385460175731,-1.4980417041570135,2.617683785993935,-0.2331011456054219,1.6791960809837663
3,040
primary active transporter
10
22
3.109591
0.001873
O75381,Q15388,Q96B49,Q9NS69,O43826,Q9BUN8,P98194,Q8N4H5,P16615,Q6P4A7
Functions
Panther Protein class
panther_protein_class
130,394,102,9,332,110,364,49,274,311
332,422,130,967,601,563,2480,1134,274,935,1102,364,394,1542,311,49,863,102,110,1548,1260,9
1.1902781082588905,0.9597126649630634,2.0145588418698184,0.24942576442222106,0.6585257316553426,0.7077431607617762,-0.7279101605274243,0.10200596012172755,1.3686274111665022,0.2758379519036087,0.1290854902149427,1.0760928564449042,1.0181828688945016,-0.1616845798336536,1.2689492993639755,2.6445862744892894,0.3543739888991153,2.218920411804227,2.1612105866232185,-0.1616845798336536,0.020010396372018485,3.4820604215174513
3,040
Cytochrome complex assembly
7
14
3.098509
0.001945
Q9BSK2,Q6DKK2,P53701,Q9Y2R0,Q15070,Q69YU5,Q7KZN9
Processes and pathways
GO Biological process
msigdb_gobp
33,232,178,17,120,62,222
428,595,178,120,62,232,222,248,650,1256,1230,33,1792,17
0.9479503532206887,0.6708680977120229,1.7621804442172937,2.0932019556415513,2.4906037531718463,1.5205208514694646,1.5632363492107093,1.477505845798672,0.6088998135451131,0.020010396372018485,0.033756111184921174,2.933230716402563,-0.30540519590093435,3.176547547397983
3,040
Inorganic ion transmembrane transport
46
106
3.087911
0.002016
Q9UDW1,Q9HD47,P06576,Q96HE7,P0DP25,Q8N4V1,Q9H4I9,Q9BPX6,P05141,P16615,Q9UM00,Q9HD20,P13073,P00846,Q9H936,Q9P246,Q96GC9,O95202,Q8IYU8,P05023,P36543,P24539,Q8N697,O14548,P56134,Q13423,O43826,Q9UHG3,P51790,P12235,O75964,P27105,Q7KZN9,P21796,Q9HC07,Q02978,Q9H0U3,P08195,Q9UBX3,P00403,O95747,O00400,P51798,P98194,P46939,Q96PU5
Processes and pathways
GO Biological process
msigdb_gobp
2,259,387,649,765,143,16,659,653,274,795,150,398,34,296,820,175,50,435,563,564,322,588,702,454,204,332,121,596,345,90,221,222,96,97,736,487,732,104,731,234,109,754,364,753,632
109,948,702,1169,332,2100,811,1030,1976,1297,1032,90,50,234,731,34,563,653,1269,387,1893,1844,732,1694,765,2034,1348,345,398,274,2759,935,861,1644,2433,3006,96,322,1979,221,2417,2838,1622,1225,2839,1187,564,2434,2372,753,1320,893,596,754,1102,896,454,1001,1411,1020,1118,919,1822,364,849,1302,736,1077,1337,2957,204,1679,1901,222,911,435,143,588,1358,1053,175,649,632,2975,1111,1830,659,1230,487,1860,1466,16,296,97,150,259,820,104,2,1737,121,1712,1221,795,1167,1068
2.170865945299008,0.2626466181221558,0.5336786310815371,0.0748011186548802,1.1902781082588905,-0.4827041033346785,0.4190345519703002,0.19624424562674062,-0.4229989506921864,-0.007578087459911156,0.19624424562674062,2.276103138392118,2.635631465461991,1.509795357420363,0.49570894697737444,2.9075240878120137,0.7077431607617762,0.5964286373641703,0.006232385460175731,1.0298093080175974,-0.3786211358393844,-0.3492237281963389,0.49570894697737444,-0.26191492372509495,0.4702605562765458,-0.45277442063761514,-0.04920595720837689,1.1448616242246488,1.0065340223336994,1.3686274111665022,-1.0004827835760666,0.2758379519036087,0.3543739888991153,-0.2331011456054219,-0.6966810077118192,-1.9267497642243225,2.247577005884701,1.2241190154546975,-0.4229989506921864,1.5632363492107093,-0.6811299828485751,-1.1334162316136511,-0.21874759683495115,0.033756111184921174,-1.1334162316136511,0.061151309647997754,0.7077431607617762,-0.6966810077118192,-0.6501537901627932,0.48299836247200467,-0.021421189614910855,0.31523626177182246,0.6708680977120229,0.48299836247200467,0.1290854902149427,0.31523626177182246,0.9006702914867534,0.22289491850198123,-0.09113208586471662,0.2095846341582732,0.11556131040259485,0.2889999091039554,-0.33458074379489317,1.0760928564449042,0.36736263752585335,-0.007578087459911156,0.49570894697737444,0.15604096067010367,-0.03529708956303091,-1.4267397471439798,1.6372812858760162,-0.24749019058283162,-0.3786211358393844,1.5632363492107093,0.3021326319906221,0.9361650584683445,1.954917564819329,0.6831850488258874,-0.04920595720837689,0.18287360405382397,1.7724755011768645,0.6088998135451131,0.6337642954290207,-1.5521212839747416,0.1290854902149427,-0.33458074379489317,0.5964286373641703,0.033756111184921174,0.8530161446660425,-0.3492237281963389,-0.11925085360259,3.2175824750230393,1.3134519523684933,2.247577005884701,1.9248809148764459,1.4233088612462526,0.4190345519703002,2.199742892007449,3.7813362177920875,-0.2763755385948963,2.0932019556415513,-0.26191492372509495,0.047469694504802575,0.44470276814533355,0.08841928230327178,0.16947255944840645
3,040
Inner mitochondrial membrane organization
18
24
3.087133
0.002021
Q9P0J0,Q53H12,O60313,Q16891,Q13505,Q9Y5J9,O75431,Q9H3K2,O60220,P17152,Q9Y512,O95202,Q96E52,Q9BUR5,Q5XKP0,Q9NX63,Q9Y584,P62072
Processes and pathways
GO Biological process
msigdb_gobp
451,548,292,672,39,264,169,231,233,460,498,50,179,116,212,633,60,29
233,292,169,967,50,460,2435,29,39,672,548,212,1126,179,116,231,689,633,451,1068,498,60,264,2909
1.509795357420363,1.3245270326423748,1.7930143140179442,0.24942576442222106,2.635631465461991,0.8887920767692477,-0.6966810077118192,3.0266138343517364,2.7598629433409028,0.57140782105902,0.7443925370224047,1.5950791374165418,0.11556131040259485,1.751868203937735,2.1127087039343455,1.5312276267961478,0.5588579410317828,0.6337642954290207,0.9125251267176329,0.16947255944840645,0.8290467604251529,2.4997661556800703,1.4124116297329234,-1.269549423261982
3,040
Nucleotide transport
11
14
3.084648
0.002038
Q8TDW0,Q9BSK2,Q08722,Q9H2D1,O43808,O00400,Q6NUK1,P12235,P12236,Q8TB61,Q99808
Processes and pathways
GO Biological process
msigdb_gobp
550,33,323,8,390,109,82,345,314,157,286
109,390,653,345,314,1189,323,82,157,550,286,33,8,561
2.170865945299008,1.0181828688945016,0.5964286373641703,1.1448616242246488,1.2577726487807976,0.061151309647997754,1.2241190154546975,2.351544747161577,1.8643679316323016,0.7443925370224047,1.3466170528239039,2.933230716402563,3.4977473541425774,0.7199845468995671
3,040
Organophosphate ester transmembrane transporter activity
9
13
3.083389
0.002047
Q9BSK2,Q9H2D1,O00400,O43826,Q6NUK1,P12235,P12236,Q8TB61,Q99808
Functions
GO Molecular function
msigdb_gomf
33,8,109,332,82,345,314,157,286
109,390,332,653,345,314,1189,82,157,286,33,8,561
2.170865945299008,1.0181828688945016,1.1902781082588905,0.5964286373641703,1.1448616242246488,1.2577726487807976,0.061151309647997754,2.351544747161577,1.8643679316323016,1.3466170528239039,2.933230716402563,3.4977473541425774,0.7199845468995671
3,040
Mitochondrial respiratory chain complex assembly
21
40
3.082627
0.002052
Q86Y39,Q9Y2R0,O95831,O43676,Q9BSK2,O75438,O75306,O96000,Q9H061,O43819,P51970,Q96E52,Q96CU9,P03886,Q69YU5,Q9P0J0,O95168,Q6DKK2,Q9Y512,Q8N8Q8,Q15070
Processes and pathways
GO Biological process
msigdb_gobp
145,17,23,32,33,290,413,545,42,428,556,179,55,187,62,451,459,232,498,248,120
32,428,1030,413,290,1171,595,459,1070,23,545,187,2985,556,1076,120,2694,1279,62,232,145,842,248,55,179,650,1256,1230,33,1788,42,1440,902,1232,451,1792,17,1950,498,2430
2.9588343365432377,0.9479503532206887,0.19624424562674062,0.9831687287835464,1.3355820397418836,0.0748011186548802,0.6708680977120229,0.8887920767692477,0.15604096067010367,3.085338247748161,0.7443925370224047,1.6896303788651301,-1.680384786537059,0.7199845468995671,0.15604096067010367,2.0932019556415513,-0.9189528352734494,0.006232385460175731,2.4906037531718463,1.5205208514694646,1.944921479987834,0.3803228835675519,1.477505845798672,2.5996850958566853,1.751868203937735,0.6088998135451131,0.020010396372018485,0.033756111184921174,2.933230716402563,-0.30540519590093435,2.73344577811532,-0.10517455077210873,0.31523626177182246,0.033756111184921174,0.9125251267176329,-0.30540519590093435,3.176547547397983,-0.3933759714785898,0.8290467604251529,-0.6811299828485751
3,040
Snap receptor activity
12
19
3.075798
0.002099
O15155,O14653,Q86Y82,Q9P2W9,Q9UEU0,Q13277,P56962,O43752,O15400,Q13190,O95721,Q12981
Functions
GO Molecular function
msigdb_gomf
321,481,484,69,297,365,305,51,466,217,476,377
2571,481,321,466,796,51,704,1170,523,476,1018,305,377,217,365,484,69,297,1791
-0.8067363769252331,0.8530161446660425,1.2241190154546975,0.8768903817981308,0.43188252856076326,2.626663982355961,0.5336786310815371,0.0748011186548802,0.7687015520901122,0.864965105135409,0.2095846341582732,1.2912412532455868,1.0529953384136446,1.5844831960754728,1.0760928564449042,0.8530161446660425,2.4445910304154994,1.3134519523684933,-0.30540519590093435
3,040
Snare interactions in vesicular transport
12
19
3.075798
0.002099
O15155,O14653,Q86Y82,Q9P2W9,Q9UEU0,Q13277,P56962,O43752,O15400,Q13190,O95721,Q12981
Processes and pathways
KEGG Pathways
msigdb_kegg
321,481,484,69,297,365,305,51,466,217,476,377
2571,481,321,466,796,51,704,1170,523,476,1018,305,377,217,365,484,69,297,1791
-0.8067363769252331,0.8530161446660425,1.2241190154546975,0.8768903817981308,0.43188252856076326,2.626663982355961,0.5336786310815371,0.0748011186548802,0.7687015520901122,0.864965105135409,0.2095846341582732,1.2912412532455868,1.0529953384136446,1.5844831960754728,1.0760928564449042,0.8530161446660425,2.4445910304154994,1.3134519523684933,-0.30540519590093435
3,040
Cation transmembrane transport
39
112
3.075034
0.002105
Q9UDW1,Q9HD47,P06576,Q96HE7,Q8N4V1,Q9H4I9,Q9BPX6,P16615,Q9HD20,P13073,P00846,Q9H936,Q96GC9,Q9HC21,O95202,Q8IYU8,Q9Y619,Q70HW3,P05023,Q6PML9,P36543,P24539,Q8N697,P56134,P05067,Q13423,P51790,P12235,O75964,P27105,Q7KZN9,P21796,Q9HC07,Q9H0U3,O95747,O00400,Q8NEW0,P98194,Q96PU5
Processes and pathways
GO Biological process
msigdb_gobp
2,259,387,649,143,16,659,274,150,398,34,296,175,561,50,435,52,53,563,312,564,322,588,454,73,204,596,345,90,221,222,96,97,487,234,109,492,364,632
109,948,702,1169,1504,2100,811,1030,1976,1297,1032,90,50,234,731,34,563,73,653,1269,387,1893,2823,1844,732,1694,765,2034,1348,345,398,274,2759,935,861,1644,2433,3006,96,322,1979,221,2417,2838,1622,1225,2839,1187,564,2434,2372,753,1320,893,596,1102,896,454,1001,1411,1020,1118,919,1822,364,849,1302,1077,1337,2957,204,1679,1901,2165,1542,312,53,222,911,435,143,588,1358,492,1053,175,649,632,2975,1111,1830,659,1230,487,1860,1466,16,296,1548,97,561,150,259,820,2,1737,1712,1221,795,1167,1068,52
2.170865945299008,0.2626466181221558,0.5336786310815371,0.0748011186548802,-0.14750568765470307,-0.4827041033346785,0.4190345519703002,0.19624424562674062,-0.4229989506921864,-0.007578087459911156,0.19624424562674062,2.276103138392118,2.635631465461991,1.509795357420363,0.49570894697737444,2.9075240878120137,0.7077431607617762,2.4168212862539087,0.5964286373641703,0.006232385460175731,1.0298093080175974,-0.3786211358393844,-1.0998893428363394,-0.3492237281963389,0.49570894697737444,-0.26191492372509495,0.4702605562765458,-0.45277442063761514,-0.04920595720837689,1.1448616242246488,1.0065340223336994,1.3686274111665022,-1.0004827835760666,0.2758379519036087,0.3543739888991153,-0.2331011456054219,-0.6966810077118192,-1.9267497642243225,2.247577005884701,1.2241190154546975,-0.4229989506921864,1.5632363492107093,-0.6811299828485751,-1.1334162316136511,-0.21874759683495115,0.033756111184921174,-1.1334162316136511,0.061151309647997754,0.7077431607617762,-0.6966810077118192,-0.6501537901627932,0.48299836247200467,-0.021421189614910855,0.31523626177182246,0.6708680977120229,0.1290854902149427,0.31523626177182246,0.9006702914867534,0.22289491850198123,-0.09113208586471662,0.2095846341582732,0.11556131040259485,0.2889999091039554,-0.33458074379489317,1.0760928564449042,0.36736263752585335,-0.007578087459911156,0.15604096067010367,-0.03529708956303091,-1.4267397471439798,1.6372812858760162,-0.24749019058283162,-0.3786211358393844,-0.5127897509611888,-0.1616845798336536,1.2689492993639755,2.6086908370116504,1.5632363492107093,0.3021326319906221,0.9361650584683445,1.954917564819329,0.6831850488258874,-0.04920595720837689,0.8410433975918085,0.18287360405382397,1.7724755011768645,0.6088998135451131,0.6337642954290207,-1.5521212839747416,0.1290854902149427,-0.33458074379489317,0.5964286373641703,0.033756111184921174,0.8530161446660425,-0.3492237281963389,-0.11925085360259,3.2175824750230393,1.3134519523684933,-0.1616845798336536,2.247577005884701,0.7199845468995671,1.9248809148764459,1.4233088612462526,0.4190345519703002,3.7813362177920875,-0.2763755385948963,-0.26191492372509495,0.047469694504802575,0.44470276814533355,0.08841928230327178,0.16947255944840645,2.617683785993935
3,040
Nucleobase containing compound transmembrane transporter activity
9
14
3.070707
0.002136
Q9BSK2,Q9H2D1,O00400,L0R6Q1,Q6NUK1,P12235,P12236,Q8TB61,Q99808
Functions
GO Molecular function
msigdb_gomf
33,8,109,140,82,345,314,157,286
140,109,390,653,345,314,1189,716,82,157,286,33,8,561
1.964897593179475,2.170865945299008,1.0181828688945016,0.5964286373641703,1.1448616242246488,1.2577726487807976,0.061151309647997754,0.5210489561099639,2.351544747161577,1.8643679316323016,1.3466170528239039,2.933230716402563,3.4977473541425774,0.7199845468995671
3,040
Endoplasmic reticulum organization
21
45
3.070154
0.002139
O95197,P57088,Q8N4V1,Q9NPA0,Q15363,Q96A33,Q8N5M9,O14657,Q15041,O43765,Q15006,Q6NUK4,Q9P2W9,Q9NQC3,Q15629,Q00765,P61026,P46379,Q8NHH9,Q12981,Q9H6H4
Processes and pathways
GO Biological process
msigdb_gobp
135,403,143,273,19,154,285,412,425,433,439,324,69,71,79,336,469,335,244,377,256
1473,2745,1096,412,679,890,2059,612,433,2227,135,1619,335,817,823,403,469,1020,336,1004,377,439,425,1541,19,79,1036,639,922,324,923,143,285,1160,244,154,1879,1767,256,1129,273,71,496,1947,69
-0.1333611726485954,-0.984083002121523,0.1290854902149427,0.9831687287835464,0.5588579410317828,0.31523626177182246,-0.46771987659621755,0.6461578360344038,0.9361650584683445,-0.5582145656983658,1.9947418992044237,-0.21874759683495115,1.1789557953519179,0.4190345519703002,0.4061587071946509,1.0065340223336994,0.8768903817981308,0.2095846341582732,1.1789557953519179,0.22289491850198123,1.0529953384136446,0.9243566825638713,0.9597126649630634,-0.1616845798336536,3.1269576003524127,2.360911550267849,0.19624424562674062,0.6213449936127172,0.2889999091039554,1.2241190154546975,0.2889999091039554,1.954917564819329,1.3466170528239039,0.08841928230327178,1.488287926722168,1.904775442700116,-0.36390379043786164,-0.29087223037784743,1.4341867150381478,0.11556131040259485,1.37960291235598,2.435348044661633,0.8410433975918085,-0.3933759714785898,2.4445910304154994
3,040
Sterol binding
6
17
3.058474
0.002225
P21796,Q14849,O15118,Q96SU4,P45880,Q14108
Functions
GO Molecular function
msigdb_gomf
96,43,238,184,123,124
238,2131,1531,269,1844,96,2552,1241,645,123,828,124,43,184,1523,1009,1287
1.4990510731461264,-0.4977273208231059,-0.1616845798336536,1.3905587313935528,-0.3492237281963389,2.247577005884701,-0.7908840017599092,0.020010396372018485,0.6088998135451131,2.0834256614858373,0.39325486209580973,2.0834256614858373,2.706918315651424,1.7208277548364277,-0.14750568765470307,0.22289491850198123,0.006232385460175731
3,040
Protein localization to mitochondrion
29
59
3.055869
0.002244
Q10713,O60830,Q99595,Q9Y371,Q9Y5J9,Q9NS69,Q15388,Q5JRX3,P51572,Q9GZY8,O95831,O43464,P62072,Q53H12,O95429,Q8N4H5,Q9Y584,O14737,Q9P0J0,Q9Y6C9,O14925,O43615,O00165,Q99797,O60220,Q9Y512,Q8N8Q8,Q15070,P55786
Processes and pathways
GO Biological process
msigdb_gobp
131,5,6,389,264,9,394,526,391,530,23,408,29,548,421,49,60,317,451,192,202,340,473,495,233,498,248,120,247
473,1951,1096,317,202,408,340,233,5,1237,1297,967,636,421,1776,23,601,2576,765,2805,1240,1978,1868,2926,2418,2943,817,391,1101,247,29,1676,131,120,394,2753,566,548,526,2121,49,248,757,6,495,530,1260,9,760,451,2269,946,1792,389,498,60,264,2909,192
0.864965105135409,-0.40816850621130574,0.1290854902149427,1.2465754397744402,1.6372812858760162,0.9948626739598494,1.1562476399214794,1.509795357420363,3.5833547818711566,0.020010396372018485,-0.007578087459911156,0.24942576442222106,0.6213449936127172,0.9714520911959001,-0.30540519590093435,3.085338247748161,0.6585257316553426,-0.8067363769252331,0.4702605562765458,-1.0665598073816422,0.020010396372018485,-0.4229989506921864,-0.36390379043786164,-1.338869380346214,-0.6811299828485751,-1.3738525898967593,0.4190345519703002,1.0181828688945016,0.1290854902149427,1.477505845798672,3.0266138343517364,-0.24749019058283162,2.0145588418698184,2.0932019556415513,1.0181828688945016,-0.984083002121523,0.7077431607617762,0.7443925370224047,0.7687015520901122,-0.4827041033346785,2.6445862744892894,1.477505845798672,0.48299836247200467,3.575618702542787,0.8410433975918085,0.7687015520901122,0.020010396372018485,3.4820604215174513,0.48299836247200467,0.9125251267176329,-0.5734361048340421,0.2758379519036087,-0.30540519590093435,1.0298093080175974,0.8290467604251529,2.4997661556800703,1.4124116297329234,-1.269549423261982,1.6791960809837663
3,040
Mitochondrial protein import
24
37
3.054852
0.002252
Q10713,P06576,O60830,Q15388,Q99595,Q9Y5J9,Q9NS69,Q5JRX3,P62072,Q13505,O75431,Q8N4H5,P12236,Q9Y584,Q3ZCQ8,Q9UJS0,O14925,O43615,P12235,P21796,O96008,Q96B49,O60220,Q9Y512
Processes and pathways
Reactome Pathways
msigdb_reactome
131,387,5,394,6,264,9,526,29,39,169,49,314,60,566,464,202,340,345,96,601,102,233,498
202,340,233,5,2746,169,1297,880,967,601,387,1694,2805,345,314,96,1979,2435,29,131,39,394,566,526,49,102,6,2696,1260,9,633,464,1792,498,60,264,2909
1.6372812858760162,1.1562476399214794,1.509795357420363,3.5833547818711566,-0.984083002121523,1.7930143140179442,-0.007578087459911156,0.3283109386072143,0.24942576442222106,0.6585257316553426,1.0298093080175974,-0.26191492372509495,-1.0665598073816422,1.1448616242246488,1.2577726487807976,2.247577005884701,-0.4229989506921864,-0.6966810077118192,3.0266138343517364,2.0145588418698184,2.7598629433409028,1.0181828688945016,0.7077431607617762,0.7687015520901122,2.6445862744892894,2.218920411804227,3.575618702542787,-0.9189528352734494,0.020010396372018485,3.4820604215174513,0.6337642954290207,0.8887920767692477,-0.30540519590093435,0.8290467604251529,2.4997661556800703,1.4124116297329234,-1.269549423261982
3,040
Cristae formation
13
21
3.050784
0.002282
P00846,P06576,Q16891,P24539,P56134,Q13505,O75431,P17152,Q9Y512,Q9BUR5,Q5XKP0,Q9NX63,O75964
Processes and pathways
Reactome Pathways
msigdb_reactome
34,387,672,322,454,39,169,460,498,116,212,633,90
169,1032,90,34,387,460,322,1979,1187,2435,1320,454,1001,39,672,212,1126,116,689,633,498
1.7930143140179442,0.19624424562674062,2.276103138392118,2.9075240878120137,1.0298093080175974,0.8887920767692477,1.2241190154546975,-0.4229989506921864,0.061151309647997754,-0.6966810077118192,-0.021421189614910855,0.9006702914867534,0.22289491850198123,2.7598629433409028,0.57140782105902,1.5950791374165418,0.11556131040259485,2.1127087039343455,0.5588579410317828,0.6337642954290207,0.8290467604251529
3,040
Organic anion transmembrane transporter activity
19
27
3.045231
0.002325
Q9H2D1,O43808,P05141,Q8TB61,Q99808,Q9H936,Q9HC21,Q9Y619,P12236,Q8N697,Q9UJS0,Q6NUK1,P12235,Q14728,Q02978,P08195,Q9UBX3,O00400,P53985
Functions
GO Molecular function
msigdb_gomf
8,390,653,157,286,296,561,52,314,588,464,82,345,218,736,732,104,109,628
109,390,880,1046,653,732,750,345,314,1189,895,628,736,218,1542,82,2443,588,157,286,8,296,1548,561,104,464,52
2.170865945299008,1.0181828688945016,0.3283109386072143,0.18287360405382397,0.5964286373641703,0.49570894697737444,0.48299836247200467,1.1448616242246488,1.2577726487807976,0.061151309647997754,0.31523626177182246,0.6337642954290207,0.49570894697737444,1.5844831960754728,-0.1616845798336536,2.351544747161577,-0.6966810077118192,0.6831850488258874,1.8643679316323016,1.3466170528239039,3.4977473541425774,1.3134519523684933,-0.1616845798336536,0.7199845468995671,2.199742892007449,0.8887920767692477,2.617683785993935
3,040
Cherry red spot of the macula
6
9
3.031602
0.002433
P16278,P06865,Q13510,P17900,P10619,P07602
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
99,101,38,111,153,155
101,155,1204,153,2482,99,111,38,166
2.218920411804227,1.8946982228718794,0.047469694504802575,1.904775442700116,-0.7279101605274243,2.228487185887663,2.151540289571206,2.7774136025275533,1.813485136764922
3,040
Protein transmembrane transport
11
25
3.028054
0.002461
O75381,O60830,Q99595,Q9NS69,O14925,Q9Y584,Q15629,Q99442,O95831,Q9Y5Y5,O43615
Processes and pathways
GO Biological process
msigdb_gobp
130,5,6,9,202,60,79,342,23,289,340
202,340,5,130,967,23,601,2805,799,547,823,1696,2109,1020,790,394,79,566,342,6,1260,9,846,60,289
1.6372812858760162,1.1562476399214794,3.5833547818711566,2.0145588418698184,0.24942576442222106,3.085338247748161,0.6585257316553426,-1.0665598073816422,0.43188252856076326,0.7443925370224047,0.4061587071946509,-0.26191492372509495,-0.4827041033346785,0.2095846341582732,0.44470276814533355,1.0181828688945016,2.360911550267849,0.7077431607617762,1.1562476399214794,3.575618702542787,0.020010396372018485,3.4820604215174513,0.3803228835675519,2.4997661556800703,1.3466170528239039
3,040
Vacuolar lumen
29
67
3.026953
0.00247
P78371,P53634,P50897,P10619,P07602,Q9BTY2,P46976,Q9NZJ7,Q13510,P54802,Q9H7Z7,P06280,O00560,P04062,Q99538,P15586,O14773,Q9UMR5,P08236,Q9UM22,Q8NHP8,P16278,P06865,P11117,P17900,P38435,Q8IV08,P10253,Q14108
Localization
GO Cellular component
msigdb_gocc
515,524,15,153,155,415,546,166,38,167,444,313,190,63,578,196,330,85,211,219,350,99,101,490,111,239,117,376,124
573,190,778,762,330,612,933,63,827,313,101,1893,1084,155,1204,2576,211,376,153,490,906,2837,196,99,111,1959,2645,239,3009,546,2038,15,2618,2235,524,1321,167,1753,1335,828,1512,515,2256,2186,1322,1324,38,124,2812,117,2194,350,774,1436,1807,1419,578,1913,415,831,2859,444,1770,166,219,85,2521
0.6954766988270652,1.6791960809837663,0.45749540095397245,0.4702605562765458,1.2015793591735133,0.6461578360344038,0.2758379519036087,2.4814280266167166,0.39325486209580973,1.2577726487807976,2.218920411804227,-0.3786211358393844,0.1425786554172647,1.8946982228718794,0.047469694504802575,-0.8067363769252331,1.5950791374165418,1.0529953384136446,1.904775442700116,0.8410433975918085,0.3021326319906221,-1.1334162316136511,1.6582743358244223,2.228487185887663,2.151540289571206,-0.40816850621130574,-0.870589512103763,1.4990510731461264,-2.004819626017603,0.7443925370224047,-0.45277442063761514,3.2339235068205605,-0.8385736772120257,-0.5582145656983658,0.7687015520901122,-0.021421189614910855,1.803258193474141,-0.29087223037784743,-0.03529708956303091,0.39325486209580973,-0.14750568765470307,0.7808192166024813,-0.5734361048340421,-0.5278916176011564,-0.021421189614910855,-0.021421189614910855,2.7774136025275533,2.0834256614858373,-1.0665598073816422,2.10296295242631,-0.5278916176011564,1.1220252798248234,0.4702605562765458,-0.10517455077210873,-0.31997463365124035,-0.09113208586471662,0.6954766988270652,-0.3786211358393844,0.9831687287835464,0.39325486209580973,-1.1502544833347488,0.9243566825638713,-0.29087223037784743,1.813485136764922,1.5844831960754728,2.3139372650206984,-0.7435887937700587
3,040
Abnormal tissue metabolite concentration
7
14
3.02679
0.002472
O75381,P06865,Q9NZJ7,P17900,P40855,P07602,Q9Y5Y5
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
130,101,166,111,181,155,289
612,130,313,101,155,1204,111,181,823,1536,2050,166,1792,289
0.6461578360344038,2.0145588418698184,1.2577726487807976,2.218920411804227,1.8946982228718794,0.047469694504802575,2.151540289571206,1.74153871768061,0.4061587071946509,-0.1616845798336536,-0.45277442063761514,1.813485136764922,-0.30540519590093435,1.3466170528239039
3,040
SNARE protein
11
17
3.018603
0.002539
O15155,O14653,Q86Y82,Q9P2W9,Q9UEU0,Q13277,P56962,O43752,O15400,Q13190,O95721
Functions
Panther Protein class
panther_protein_class
321,481,484,69,297,365,305,51,466,217,476
2571,481,321,466,51,704,523,476,1018,305,217,365,484,1442,69,297,1791
-0.8067363769252331,0.8530161446660425,1.2241190154546975,0.8768903817981308,2.626663982355961,0.5336786310815371,0.7687015520901122,0.864965105135409,0.2095846341582732,1.2912412532455868,1.5844831960754728,1.0760928564449042,0.8530161446660425,-0.10517455077210873,2.4445910304154994,1.3134519523684933,-0.30540519590093435
3,040
Transport vesicle
34
98
3.005094
0.002655
O15260,P24390,O00461,P50897,Q96A57,Q9GZY8,O95249,Q15363,P49755,Q9NR31,Q9UEU0,O43760,Q8TBA6,Q9BVK6,P56962,O43752,Q15907,O15155,P10321,P05067,Q7Z6M1,Q92542,P16870,P61026,Q9Y3B3,P51790,Q13190,O15400,O76024,O14653,Q86Y82,Q13277,Q7L0J3,O43731
Localization
GO Cellular component
msigdb_gocc
128,10,138,15,271,530,523,19,547,416,297,45,300,559,305,51,308,321,575,73,331,457,583,469,87,596,217,466,475,481,484,365,370,127
1096,138,787,481,890,763,321,128,466,796,127,2148,51,45,704,2596,1669,2181,1170,475,2227,523,1572,1843,2298,905,813,73,953,1621,765,575,1317,1925,583,935,1845,2232,10,2417,1645,1624,2434,2001,817,547,15,1153,2877,1274,596,1018,2420,1575,1932,305,2206,1389,469,1208,1411,2460,1934,2604,217,365,1629,1459,2352,1566,2165,19,2167,308,370,331,484,300,457,607,825,271,718,719,559,530,832,416,2247,2932,2317,297,1737,2654,87,1668,728,1716
0.1290854902149427,1.9848097046957438,0.44470276814533355,0.8530161446660425,0.31523626177182246,0.4702605562765458,1.2241190154546975,2.034312887492732,0.8768903817981308,0.43188252856076326,2.0441664596066604,-0.5127897509611888,2.626663982355961,2.6891715667114098,0.5336786310815371,-0.8226328459755452,-0.24749019058283162,-0.5278916176011564,0.0748011186548802,0.864965105135409,-0.5582145656983658,0.7687015520901122,-0.19014622799961578,-0.3492237281963389,-0.604000472797998,0.3021326319906221,0.4190345519703002,2.4168212862539087,0.2626466181221558,-0.21874759683495115,0.4702605562765458,0.6954766988270652,-0.021421189614910855,-0.3933759714785898,0.6831850488258874,0.2758379519036087,-0.3492237281963389,-0.5582145656983658,3.474202711443219,-0.6811299828485751,-0.2331011456054219,-0.21874759683495115,-0.6966810077118192,-0.43786751739574514,0.4190345519703002,0.7443925370224047,3.2339235068205605,0.08841928230327178,-1.1840822292813866,0.006232385460175731,0.6708680977120229,0.2095846341582732,-0.6811299828485751,-0.19014622799961578,-0.3933759714785898,1.2912412532455868,-0.5430331465710542,-0.07712328202431389,0.8768903817981308,0.047469694504802575,-0.09113208586471662,-0.712274316441883,-0.3933759714785898,-0.8226328459755452,1.5844831960754728,1.0760928564449042,-0.21874759683495115,-0.11925085360259,-0.634728130674405,-0.1758980318826104,-0.5127897509611888,3.1269576003524127,-0.5127897509611888,1.280105473646303,1.0645551154147626,1.2015793591735133,0.8530161446660425,1.302356719279247,0.9006702914867534,0.6585257316553426,0.4061587071946509,1.3905587313935528,0.5210489561099639,0.5210489561099639,0.7199845468995671,0.7687015520901122,0.39325486209580973,0.9831687287835464,-0.5582145656983658,-1.338869380346214,-0.604000472797998,1.3134519523684933,-0.2763755385948963,-0.870589512103763,2.2950487183120347,-0.2331011456054219,0.5083924363167223,-0.26191492372509495
3,040
membrane trafficking regulatory protein
6
19
2.97898
0.002892
P24390,O43760,Q14108,Q9P253,O00560,O43731
Functions
Panther Protein class
panther_protein_class
10,45,124,253,190,127
993,1774,190,127,45,1619,1317,10,823,124,2307,2165,255,1659,1606,2447,2247,1947,253
0.22289491850198123,-0.30540519590093435,1.6791960809837663,2.0441664596066604,2.6891715667114098,-0.21874759683495115,-0.021421189614910855,3.474202711443219,0.4061587071946509,2.0834256614858373,-0.604000472797998,-0.5127897509611888,1.4341867150381478,-0.2331011456054219,-0.20442935390032577,-0.6966810077118192,-0.5582145656983658,-0.3933759714785898,1.4558845889071608
3,040
Lysosome
20
50
2.976177
0.002919
P50897,Q93050,O75503,P10619,P07602,Q9NZJ7,Q13510,P54802,P06280,P04062,P15586,O14773,Q9UMR5,P08236,P16278,P06865,Q9Y487,O15118,P17900,Q14108
Processes and pathways
KEGG Pathways
msigdb_kegg
15,146,148,153,155,166,38,167,313,63,196,330,85,211,99,101,105,238,111,124
1951,573,762,2875,330,238,612,2148,148,63,827,313,101,155,1204,211,953,1621,376,153,490,1317,1925,196,99,111,2232,3009,15,524,167,1411,828,2604,2161,38,124,1123,772,607,146,718,578,1881,166,1712,1343,85,836,105
-0.40816850621130574,0.6954766988270652,0.4702605562765458,-1.1840822292813866,1.2015793591735133,1.4990510731461264,0.6461578360344038,-0.5127897509611888,1.9349092822529808,2.4814280266167166,0.39325486209580973,1.2577726487807976,2.218920411804227,1.8946982228718794,0.047469694504802575,1.5950791374165418,0.2626466181221558,-0.21874759683495115,1.0529953384136446,1.904775442700116,0.8410433975918085,-0.021421189614910855,-0.3933759714785898,1.6582743358244223,2.228487185887663,2.151540289571206,-0.5582145656983658,-2.004819626017603,3.2339235068205605,0.7687015520901122,1.803258193474141,-0.09113208586471662,0.39325486209580973,-0.8226328459755452,-0.5127897509611888,2.7774136025275533,2.0834256614858373,0.11556131040259485,0.4702605562765458,0.6585257316553426,1.944921479987834,0.5210489561099639,0.6954766988270652,-0.36390379043786164,1.813485136764922,-0.26191492372509495,-0.03529708956303091,2.3139372650206984,0.39325486209580973,2.199742892007449
3,040
Nucleotide transmembrane transporter activity
8
12
2.972287
0.002956
Q9BSK2,Q9H2D1,O00400,Q6NUK1,P12235,P12236,Q8TB61,Q99808
Functions
GO Molecular function
msigdb_gomf
33,8,109,82,345,314,157,286
109,390,653,345,314,1189,82,157,286,33,8,561
2.170865945299008,1.0181828688945016,0.5964286373641703,1.1448616242246488,1.2577726487807976,0.061151309647997754,2.351544747161577,1.8643679316323016,1.3466170528239039,2.933230716402563,3.4977473541425774,0.7199845468995671
3,040
Snare complex
12
21
2.967429
0.003003
O15155,O14653,Q86Y82,Q9P2W9,Q9UEU0,Q13277,P56962,O43752,O15400,Q13190,O95721,Q12981
Localization
GO Cellular component
msigdb_gocc
321,481,484,69,297,365,305,51,466,217,476,377
2571,481,321,466,796,51,704,1170,523,476,1018,1454,305,377,217,365,484,1787,69,297,1791
-0.8067363769252331,0.8530161446660425,1.2241190154546975,0.8768903817981308,0.43188252856076326,2.626663982355961,0.5336786310815371,0.0748011186548802,0.7687015520901122,0.864965105135409,0.2095846341582732,-0.11925085360259,1.2912412532455868,1.0529953384136446,1.5844831960754728,1.0760928564449042,0.8530161446660425,-0.30540519590093435,2.4445910304154994,1.3134519523684933,-0.30540519590093435
3,040
Organic acid transmembrane transport
21
28
2.965505
0.003022
Q9H2D1,Q8TDW0,Q15041,P31751,Q9H936,O75915,Q9Y619,P28288,P23786,Q8N697,Q9UJS0,P50416,O60831,Q02978,P08195,Q9UBX3,P11166,P08183,O75746,P53985,P33121
Processes and pathways
GO Biological process
msigdb_gobp
8,550,425,799,296,681,52,183,447,588,464,862,224,736,732,104,750,749,880,628,637
1504,224,880,681,1046,1269,749,732,750,447,183,799,637,1189,862,895,628,736,425,1542,588,550,8,296,1548,104,464,52
-0.14750568765470307,1.5525853052037832,0.3283109386072143,0.5588579410317828,0.18287360405382397,0.006232385460175731,0.48299836247200467,0.49570894697737444,0.48299836247200467,0.9125251267176329,1.7311919224355028,0.43188252856076326,0.6213449936127172,0.061151309647997754,0.3543739888991153,0.31523626177182246,0.6337642954290207,0.49570894697737444,0.9597126649630634,-0.1616845798336536,0.6831850488258874,0.7443925370224047,3.4977473541425774,1.3134519523684933,-0.1616845798336536,2.199742892007449,0.8887920767692477,2.617683785993935
3,040
Protein targeting to mitochondrion
28
46
2.965056
0.003026
Q10713,O60830,Q99595,Q9Y371,Q9Y5J9,Q9NS69,Q15388,Q5JRX3,P51572,Q9GZY8,O95831,O43464,P62072,Q53H12,O95429,Q8N4H5,Q9Y584,O14737,Q3ZCQ8,Q9P0J0,O14925,O43615,O00165,O96008,Q99797,O60220,Q9Y512,P55786
Processes and pathways
GO Biological process
msigdb_gobp
131,5,6,389,264,9,394,526,391,530,23,408,29,548,421,49,60,317,566,451,202,340,473,601,495,233,498,247
473,317,202,408,340,233,5,1237,1297,967,636,421,1776,23,601,2576,2805,1868,2943,817,391,247,29,1676,131,394,2753,566,548,526,2121,49,757,6,495,530,1260,9,451,2269,946,389,498,60,264,2909
0.864965105135409,1.2465754397744402,1.6372812858760162,0.9948626739598494,1.1562476399214794,1.509795357420363,3.5833547818711566,0.020010396372018485,-0.007578087459911156,0.24942576442222106,0.6213449936127172,0.9714520911959001,-0.30540519590093435,3.085338247748161,0.6585257316553426,-0.8067363769252331,-1.0665598073816422,-0.36390379043786164,-1.3738525898967593,0.4190345519703002,1.0181828688945016,1.477505845798672,3.0266138343517364,-0.24749019058283162,2.0145588418698184,1.0181828688945016,-0.984083002121523,0.7077431607617762,0.7443925370224047,0.7687015520901122,-0.4827041033346785,2.6445862744892894,0.48299836247200467,3.575618702542787,0.8410433975918085,0.7687015520901122,0.020010396372018485,3.4820604215174513,0.9125251267176329,-0.5734361048340421,0.2758379519036087,1.0298093080175974,0.8290467604251529,2.4997661556800703,1.4124116297329234,-1.269549423261982
3,040
Intracellular protein transmembrane transport
9
21
2.960315
0.003073
O75381,O60830,Q99595,O14925,Q15629,Q99442,O95831,Q9Y5Y5,O43615
Processes and pathways
GO Biological process
msigdb_gobp
130,5,6,202,79,342,23,289,340
202,340,5,130,967,23,601,2805,799,823,1696,2109,1020,394,79,566,342,6,1260,846,289
1.6372812858760162,1.1562476399214794,3.5833547818711566,2.0145588418698184,0.24942576442222106,3.085338247748161,0.6585257316553426,-1.0665598073816422,0.43188252856076326,0.4061587071946509,-0.26191492372509495,-0.4827041033346785,0.2095846341582732,1.0181828688945016,2.360911550267849,0.7077431607617762,1.1562476399214794,3.575618702542787,0.020010396372018485,0.3803228835675519,1.3466170528239039
3,040
Splenomegaly
23
85
2.951114
0.003166
Q10713,Q9NZ08,P00813,Q96A33,Q15392,P07602,Q9NZJ7,Q13510,P21964,P54802,Q14739,P28288,O95453,P04062,P15586,Q96HY6,P08236,Q86WC4,P16278,Q6NUQ1,P14174,O15118,Q14108
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
131,281,24,154,152,155,166,38,165,167,307,183,318,63,196,328,211,95,99,230,106,238,124
1951,1773,762,2875,562,238,1745,1642,2630,932,2714,318,2548,24,905,532,63,827,2993,1596,2613,2452,2540,155,211,376,750,1997,2550,1348,2936,106,196,99,1350,1978,1644,165,1072,2485,798,183,1999,1151,468,2937,3009,2137,2039,1536,754,1932,2375,167,2992,828,982,1322,131,1107,38,124,307,152,2079,1123,230,430,2050,95,1517,2940,154,1606,328,961,962,329,2801,487,560,2247,1710,281,166
-0.40816850621130574,-0.30540519590093435,0.4702605562765458,-1.1840822292813866,0.7077431607617762,1.4990510731461264,-0.29087223037784743,-0.2331011456054219,-0.854559141460524,0.2758379519036087,-0.9514247127867999,1.2465754397744402,-0.7908840017599092,3.068614648100329,0.3021326319906221,0.7565593617275889,2.4814280266167166,0.39325486209580973,-1.7550288147251754,-0.20442935390032577,-0.8385736772120257,-0.712274316441883,-0.7750754546713702,1.8946982228718794,1.5950791374165418,1.0529953384136446,0.48299836247200467,-0.43786751739574514,-0.7908840017599092,-0.04920595720837689,-1.35633374486142,2.1901320481563595,1.6582743358244223,2.228487185887663,-0.04920595720837689,-0.4229989506921864,-0.2331011456054219,1.813485136764922,0.15604096067010367,-0.7279101605274243,0.43188252856076326,1.7311919224355028,-0.43786751739574514,0.08841928230327178,0.8768903817981308,-1.35633374486142,-2.004819626017603,-0.4977273208231059,-0.45277442063761514,-0.1616845798336536,0.48299836247200467,-0.3933759714785898,-0.6501537901627932,1.803258193474141,-1.7362734726560765,0.39325486209580973,0.23617524638555046,-0.021421189614910855,2.0145588418698184,0.1290854902149427,2.7774136025275533,2.0834256614858373,1.2912412532455868,1.914836320811382,-0.46771987659621755,0.11556131040259485,1.5312276267961478,0.9479503532206887,-0.45277442063761514,2.2571001484359003,-0.14750568765470307,-1.35633374486142,1.904775442700116,-0.20442935390032577,1.2128596333356767,0.2626466181221558,0.2626466181221558,1.2128596333356767,-1.049968259128234,0.8530161446660425,0.7199845468995671,-0.5582145656983658,-0.26191492372509495,1.3576321505652418,1.813485136764922
3,040
Golgi cisterna membrane
12
19
2.941459
0.003267
Q10713,Q8NBN3,Q96L58,O00461,Q99523,P51572,P15291,P98194,Q10472,Q15363,Q08378,Q9H4A6
Localization
GO Cellular component
msigdb_gocc
131,70,493,138,718,391,624,364,210,19,500,712
138,871,624,391,364,500,1209,1175,210,131,19,70,804,1659,493,718,712,1889,728
1.9848097046957438,0.3413568016183609,0.6337642954290207,1.0181828688945016,1.0760928564449042,0.8170261289828668,0.047469694504802575,0.0748011186548802,1.6056568490181453,2.0145588418698184,3.1269576003524127,2.435348044661633,0.43188252856076326,-0.2331011456054219,0.8410433975918085,0.5210489561099639,0.5336786310815371,-0.36390379043786164,0.5083924363167223
3,040
Biliary tract abnormality
9
24
2.938554
0.003297
Q10713,Q9NZJ7,P14174,O95202,Q5XKP0,P09601,P07602,Q14108,P04062
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
131,166,106,50,212,56,155,124,63
612,50,552,532,63,155,56,106,954,1479,823,1536,131,1107,124,307,212,1987,961,1568,166,1262,1792,2966
0.6461578360344038,2.635631465461991,0.7322009687405336,0.7565593617275889,2.4814280266167166,1.8946982228718794,2.5906665227871963,2.1901320481563595,0.2626466181221558,-0.1333611726485954,0.4061587071946509,-0.1616845798336536,2.0145588418698184,0.1290854902149427,2.0834256614858373,1.2912412532455868,1.5950791374165418,-0.4229989506921864,0.2626466181221558,-0.1758980318826104,1.813485136764922,0.020010396372018485,-0.30540519590093435,-1.4980417041570135
3,040
SNARE protein
11
16
2.933847
0.003348
O15155,O14653,Q86Y82,Q9P2W9,Q9UEU0,Q13277,P56962,O43752,O15400,Q13190,O95721
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
321,481,484,69,297,365,305,51,466,217,476
2571,481,321,466,51,704,523,476,1018,305,217,365,484,69,297,1791
-0.8067363769252331,0.8530161446660425,1.2241190154546975,0.8768903817981308,2.626663982355961,0.5336786310815371,0.7687015520901122,0.864965105135409,0.2095846341582732,1.2912412532455868,1.5844831960754728,1.0760928564449042,0.8530161446660425,2.4445910304154994,1.3134519523684933,-0.30540519590093435
3,040
transporter
27
61
2.933664
0.00335
Q9C0E2,O60830,Q99595,Q9H2D1,Q8NFH4,Q9HD45,Q92973,P62072,Q99808,Q567V2,O00410,Q99805,P54105,Q9Y619,Q99567,Q6PML9,Q9Y584,Q8N697,Q92544,Q9H2V7,O43615,Q8N1F7,Q9NR77,Q8TEX9,O43681,Q8N8Q8,Q15070
Functions
Panther Protein class
panther_protein_class
520,5,6,8,516,137,411,29,286,159,543,426,299,52,442,312,60,588,591,213,340,346,225,100,612,248,120
543,1863,2875,1148,1201,340,612,1504,1149,5,950,1558,2000,1017,1189,2252,2737,894,1511,1368,895,628,299,1136,937,1020,29,782,1854,120,159,3007,312,1080,346,588,248,516,818,100,591,411,1829,889,442,6,426,286,2930,520,8,213,1010,137,225,1920,976,1221,60,2966,52
0.7443925370224047,-0.36390379043786164,-1.1840822292813866,0.08841928230327178,0.047469694504802575,1.1562476399214794,0.6461578360344038,-0.14750568765470307,0.08841928230327178,3.5833547818711566,0.2626466181221558,-0.1758980318826104,-0.43786751739574514,0.2095846341582732,0.061151309647997754,-0.5734361048340421,-0.9677304102123561,0.31523626177182246,-0.14750568765470307,-0.06314796381553464,0.31523626177182246,0.6337642954290207,1.302356719279247,0.10200596012172755,0.2758379519036087,0.2095846341582732,3.0266138343517364,0.45749540095397245,-0.3492237281963389,2.0932019556415513,1.8440649572883736,-1.9267497642243225,1.2689492993639755,0.15604096067010367,1.1334542001794992,0.6831850488258874,1.477505845798672,0.7808192166024813,0.4190345519703002,2.228487185887663,0.6831850488258874,0.9948626739598494,-0.33458074379489317,0.3283109386072143,0.9243566825638713,3.575618702542787,0.9597126649630634,1.3466170528239039,-1.338869380346214,0.7808192166024813,3.4977473541425774,1.5950791374165418,0.22289491850198123,1.9947418992044237,1.5525853052037832,-0.3786211358393844,0.24942576442222106,0.047469694504802575,2.4997661556800703,-1.4980417041570135,2.617683785993935
3,040
Secondary active transmembrane transporter activity
16
21
2.931431
0.003374
P55011,Q02978,Q8N697,P08195,Q9H936,Q9UBX3,O43826,O00400,P51798,P05141,O95202,Q00325,P51790,P12235,P53985,P12236
Functions
GO Molecular function
msigdb_gomf
896,736,588,732,296,104,332,109,754,653,50,849,596,345,628,314
109,332,50,653,732,345,314,1189,596,754,895,628,896,849,736,1542,588,1358,1053,296,104
2.170865945299008,1.1902781082588905,2.635631465461991,0.5964286373641703,0.49570894697737444,1.1448616242246488,1.2577726487807976,0.061151309647997754,0.6708680977120229,0.48299836247200467,0.31523626177182246,0.6337642954290207,0.31523626177182246,0.36736263752585335,0.49570894697737444,-0.1616845798336536,0.6831850488258874,-0.04920595720837689,0.18287360405382397,1.3134519523684933,2.199742892007449
3,040
Protein transporter activity
7
15
2.928254
0.003409
O60830,Q99595,Q9Y5J9,Q9NS69,O14925,Q9HD20,Q9Y584
Functions
GO Molecular function
msigdb_gomf
5,6,264,9,202,150,60
202,5,967,601,547,1020,790,394,1683,6,150,9,846,60,264
1.6372812858760162,3.5833547818711566,0.24942576442222106,0.6585257316553426,0.7443925370224047,0.2095846341582732,0.44470276814533355,1.0181828688945016,-0.24749019058283162,3.575618702542787,1.9248809148764459,3.4820604215174513,0.3803228835675519,2.4997661556800703,1.4124116297329234
3,040
Abnormal biliary tract morphology
8
22
2.916051
0.003545
Q10713,Q9NZJ7,P14174,Q5XKP0,P09601,P07602,Q14108,P04062
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
131,166,106,212,56,155,124,63
612,532,63,155,56,106,954,1479,823,1536,131,1107,124,307,212,1987,961,1568,166,1262,1792,2966
0.6461578360344038,0.7565593617275889,2.4814280266167166,1.8946982228718794,2.5906665227871963,2.1901320481563595,0.2626466181221558,-0.1333611726485954,0.4061587071946509,-0.1616845798336536,2.0145588418698184,0.1290854902149427,2.0834256614858373,1.2912412532455868,1.5950791374165418,-0.4229989506921864,0.2626466181221558,-0.1758980318826104,1.813485136764922,0.020010396372018485,-0.30540519590093435,-1.4980417041570135
3,040
Mental deterioration
33
102
2.909812
0.003616
Q10713,O95470,Q86SQ9,Q9BQE5,P50897,Q9UHD9,O75503,O43464,P07602,P00846,O60313,O75306,Q9NZJ7,Q13510,P21964,P54802,Q9NQZ5,O43819,P35637,P03886,P04062,P05067,Q9UBB4,Q5XKP0,P22626,P16278,P06865,Q9Y487,O60220,O15118,P17900,Q9H2C2,Q14108
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
131,261,7,13,15,407,148,408,155,34,292,413,166,38,165,167,302,428,304,187,63,73,462,212,477,99,101,105,233,238,111,372,124
1096,238,408,612,428,233,292,1643,2770,413,148,475,636,2102,261,601,731,34,187,63,2549,812,73,101,155,1204,3022,2454,859,2865,916,99,3024,111,934,534,1318,165,477,2483,848,2719,1271,304,564,2434,2036,2372,1135,2831,15,2646,2841,167,1752,1753,828,1820,2604,897,2046,2789,1754,1337,1483,131,909,1700,38,124,1176,2215,1392,212,2119,987,1582,7,1250,886,2814,1127,2678,1686,962,608,2975,1966,3012,13,1788,1916,372,540,302,2093,166,462,1039,407,1667,105
0.1290854902149427,1.4990510731461264,0.9948626739598494,0.6461578360344038,0.9479503532206887,1.509795357420363,1.3245270326423748,-0.2331011456054219,-1.0169300525091258,0.9831687287835464,1.9349092822529808,0.864965105135409,0.6213449936127172,-0.4827041033346785,1.4124116297329234,0.6585257316553426,0.49570894697737444,2.9075240878120137,1.6896303788651301,2.4814280266167166,-0.7908840017599092,0.4190345519703002,2.4168212862539087,2.218920411804227,1.8946982228718794,0.047469694504802575,-2.7627674830747737,-0.712274316441883,0.3543739888991153,-1.1671430396108629,0.2889999091039554,2.228487185887663,-2.9466997962511,2.151540289571206,0.2758379519036087,0.7565593617275889,-0.021421189614910855,1.813485136764922,0.864965105135409,-0.7279101605274243,0.36736263752585335,-0.9514247127867999,0.006232385460175731,1.2912412532455868,0.7077431607617762,-0.6966810077118192,-0.45277442063761514,-0.6501537901627932,0.10200596012172755,-1.1166279588884744,3.2339235068205605,-0.870589512103763,-1.1334162316136511,1.803258193474141,-0.29087223037784743,-0.29087223037784743,0.39325486209580973,-0.33458074379489317,-0.8226328459755452,0.31523626177182246,-0.45277442063761514,-1.0334251097631109,-0.29087223037784743,-0.03529708956303091,-0.1333611726485954,2.0145588418698184,0.3021326319906221,-0.26191492372509495,2.7774136025275533,2.0834256614858373,0.0748011186548802,-0.5430331465710542,-0.07712328202431389,1.5950791374165418,-0.4827041033346785,0.23617524638555046,-0.19014622799961578,3.5445820412147606,0.020010396372018485,0.3283109386072143,-1.0665598073816422,0.11556131040259485,-0.9027860790866954,-0.24749019058283162,0.2626466181221558,0.6585257316553426,-1.5521212839747416,-0.40816850621130574,-2.124043784992949,3.3069498983425705,-0.30540519590093435,-0.3786211358393844,1.0645551154147626,0.7565593617275889,1.302356719279247,-0.46771987659621755,1.813485136764922,0.8887920767692477,0.19624424562674062,1.0065340223336994,-0.2331011456054219,2.199742892007449
3,040
Sphingolipid biosynthetic process
10
16
2.908549
0.003631
O95470,Q13510,Q99805,Q9NXE4,Q9P035,Q06136,Q96G23,O15121,O15269,P04062
Processes and pathways
GO Biological process
msigdb_gobp
261,38,426,496,173,461,147,505,245,63
505,245,903,261,63,2552,848,1322,461,38,548,147,426,496,173,1947
0.8049813983798076,1.477505845798672,0.3021326319906221,1.4124116297329234,2.4814280266167166,-0.7908840017599092,0.36736263752585335,-0.021421189614910855,0.8887920767692477,2.7774136025275533,0.7443925370224047,1.944921479987834,0.9597126649630634,0.8410433975918085,1.782753437123811,-0.3933759714785898
3,040
Carbohydrate derivative transmembrane transporter activity
8
12
2.904677
0.003676
O00400,O43826,L0R6Q1,Q6NUK1,P12235,P12236,Q8TB61,Q99808
Functions
GO Molecular function
msigdb_gomf
109,332,140,82,345,314,157,286
140,109,390,332,653,345,314,1189,82,588,157,286
1.964897593179475,2.170865945299008,1.0181828688945016,1.1902781082588905,0.5964286373641703,1.1448616242246488,1.2577726487807976,0.061151309647997754,2.351544747161577,0.6831850488258874,1.8643679316323016,1.3466170528239039
3,040
Membrane lipid catabolic process
6
12
2.902756
0.003699
O95470,P06865,Q13510,P17900,P50897,P04062
Processes and pathways
GO Biological process
msigdb_gobp
261,101,38,111,15,63
261,63,827,313,101,1204,111,15,1322,38,609,496
1.4124116297329234,2.4814280266167166,0.39325486209580973,1.2577726487807976,2.218920411804227,0.047469694504802575,2.151540289571206,3.2339235068205605,-0.021421189614910855,2.7774136025275533,0.6585257316553426,0.8410433975918085
3,040
Liposaccharide metabolic process
7
17
2.898692
0.003747
P16278,P06865,Q5H8A4,P17900,Q92643,P06280,P04062
Processes and pathways
GO Biological process
msigdb_gobp
99,101,295,111,371,313,63
669,1745,63,827,313,101,1204,99,111,1322,295,925,371,888,619,426,1145
0.57140782105902,-0.29087223037784743,2.4814280266167166,0.39325486209580973,1.2577726487807976,2.218920411804227,0.047469694504802575,2.228487185887663,2.151540289571206,-0.021421189614910855,1.3134519523684933,0.2889999091039554,1.0645551154147626,0.3283109386072143,0.6461578360344038,0.9597126649630634,0.10200596012172755
3,040
Anion transmembrane transporter activity
29
42
2.887823
0.003879
Q9H2D1,O43808,P05141,Q8TB61,Q99808,Q8TDW0,Q9H936,Q9HC21,Q9Y619,Q9C0H2,P12236,Q8N697,Q9Y277,Q9UJS0,O43826,Q6NUK1,P51790,P12235,Q14728,P21796,Q02978,P08195,Q9UBX3,O43681,O00400,P51798,P53985,P45880,Q96S66
Functions
GO Molecular function
msigdb_gomf
8,390,653,157,286,550,296,561,52,54,314,588,199,464,332,82,596,345,218,96,736,732,104,612,109,754,628,123,641
2757,109,612,390,332,880,1046,653,732,871,750,345,314,96,1189,123,596,754,895,628,896,736,218,1542,3007,82,2443,588,157,550,641,286,54,8,296,1548,561,104,464,199,52,1690
-1.0004827835760666,2.170865945299008,0.6461578360344038,1.0181828688945016,1.1902781082588905,0.3283109386072143,0.18287360405382397,0.5964286373641703,0.49570894697737444,0.3413568016183609,0.48299836247200467,1.1448616242246488,1.2577726487807976,2.247577005884701,0.061151309647997754,2.0834256614858373,0.6708680977120229,0.48299836247200467,0.31523626177182246,0.6337642954290207,0.31523626177182246,0.49570894697737444,1.5844831960754728,-0.1616845798336536,-1.9267497642243225,2.351544747161577,-0.6966810077118192,0.6831850488258874,1.8643679316323016,0.7443925370224047,0.6213449936127172,1.3466170528239039,2.6086908370116504,3.4977473541425774,1.3134519523684933,-0.1616845798336536,0.7199845468995671,2.199742892007449,0.8887920767692477,1.6582743358244223,2.617683785993935,-0.24749019058283162
3,040
Golgi cisterna
18
25
2.88599
0.003902
Q9BXS4,O15155,Q10713,Q8NBZ7,Q8NBN3,Q96L58,O00461,Q99523,P51572,Q8TBA6,P15291,P98194,Q10472,Q15363,O95249,Q9Y6B6,Q08378,Q9H4A6
Localization
GO Cellular component
msigdb_gocc
579,321,131,804,70,493,138,718,391,300,624,364,210,19,523,728,500,712
138,321,523,813,871,624,391,364,500,1209,1175,210,131,2165,19,70,804,300,1659,493,718,579,712,1889,728
1.9848097046957438,1.2241190154546975,0.7687015520901122,0.4190345519703002,0.3413568016183609,0.6337642954290207,1.0181828688945016,1.0760928564449042,0.8170261289828668,0.047469694504802575,0.0748011186548802,1.6056568490181453,2.0145588418698184,-0.5127897509611888,3.1269576003524127,2.435348044661633,0.43188252856076326,1.302356719279247,-0.2331011456054219,0.8410433975918085,0.5210489561099639,0.6954766988270652,0.5336786310815371,-0.36390379043786164,0.5083924363167223
3,040
Hydrolase activity hydrolyzing o glycosyl compounds
9
21
2.883932
0.003927
P16278,P06865,P54802,P10253,P17900,P08236,P06280,Q9NUJ1,P04062
Functions
GO Molecular function
msigdb_gomf
99,101,167,376,111,211,313,186,63
573,762,1223,644,63,827,313,101,1204,211,376,99,111,2106,167,2046,2011,2117,1338,415,186
0.6954766988270652,0.4702605562765458,0.033756111184921174,0.6088998135451131,2.4814280266167166,0.39325486209580973,1.2577726487807976,2.218920411804227,0.047469694504802575,1.5950791374165418,1.0529953384136446,2.228487185887663,2.151540289571206,-0.4827041033346785,1.803258193474141,-0.45277442063761514,-0.43786751739574514,-0.4827041033346785,-0.03529708956303091,0.9831687287835464,1.7104461511591396
3,040