term
stringlengths
2
121
overlap
int64
6
281
setsize
int64
7
499
score
float64
1.96
10.6
pval
float64
0
0.05
edge
stringlengths
41
1.97k
type
stringclasses
5 values
subtype
stringclasses
24 values
subtype_key
stringclasses
24 values
edge_idxs
stringlengths
11
1.17k
ann_idxs
stringlengths
19
2.31k
ann_vals
stringlengths
124
9.94k
sig_size
int64
2.2k
3.73k
Purine nucleotide transport
9
11
3.209637
0.001329
P05141,P12235,P12236,Q6NUK1,O00400,Q08722,Q8TDW0,Q8TB61,Q99808
Processes and pathways
GO Biological process
msigdb_gobp
387,172,143,306,51,177,378,251,316
51,414,387,172,143,1148,177,306,251,378,316
2.623760656175141,0.9981735054914589,1.0670881313408322,1.76159249707139,1.9045369603750726,0.0839486679282727,1.7409268040090475,1.302890926914009,1.4771970637826917,1.1012827099190845,1.269704145648055
3,040
Ceramide metabolic process
12
19
3.198882
0.00138
P06280,Q96G23,Q99805,O95470,Q8NCC3,P17900,Q53H12,O15269,P04062,Q05655,Q13510,P06865
Processes and pathways
GO Biological process
msigdb_gobp
292,133,425,168,423,169,422,431,180,243,54,246
924,431,719,628,168,180,292,246,1520,169,843,982,243,54,422,423,133,425,548
0.2925877034989214,0.9634495159911116,0.5444366893129593,0.6425575843066014,1.7821961261129045,1.7305705557513118,1.3468887104804244,1.4879442405996233,-0.18655323709370267,1.7821961261129045,0.39448062923729826,0.2280960394572554,1.4986744858114172,2.532046451483146,0.9866187689477497,0.9866187689477497,1.9448386266327375,0.9866187689477497,0.7751560059742102
3,040
Liposaccharide metabolic process
12
17
3.192393
0.001411
Q92643,Q5H8A4,P06280,P16278,Q99805,P04066,P17900,O60762,Q8NBX0,Q05655,P04062,P06865
Processes and pathways
GO Biological process
msigdb_gobp
608,130,292,294,425,581,169,622,530,243,180,246
852,622,180,581,292,246,1520,294,169,243,130,530,608,1042,625,425,971
0.3818296309293903,0.6547215620472547,1.7305705557513118,0.7152105634749184,1.3468887104804244,1.4879442405996233,-0.18655323709370267,1.3359159947113879,1.7821961261129045,1.4986744858114172,1.9749109921081565,0.7989843584173286,0.678983077713463,0.1760439488988051,0.6547215620472547,0.9866187689477497,0.25396851053519315
3,040
Golgi organization
26
60
3.174666
0.0015
O75122,P49755,O75396,P40616,Q53FT3,Q9BTU6,Q9P2W9,Q9UEU0,Q9Y3B3,Q5T2E6,P48729,O15260,P61019,P56962,Q13190,Q96GC9,Q15363,O15155,Q9H4A6,Q9Y3A6,Q7Z3D4,Q9H9E3,Q12907,Q8NHH9,Q8TBA6,O43752
Processes and pathways
GO Biological process
msigdb_gobp
501,517,527,661,33,546,46,437,570,63,572,448,573,450,319,79,595,334,602,603,93,612,617,235,364,108
1554,1424,863,334,448,2544,108,1538,501,527,1556,2068,2085,661,2392,572,1227,517,1312,450,2473,573,1151,1296,2207,1411,617,319,944,595,33,63,1484,1844,93,1760,2561,2573,235,2657,364,1129,79,2702,1873,546,1077,602,1687,683,612,46,437,1379,1005,1380,1551,603,570,963
-0.21423082748473318,-0.1178697283777986,0.3691543755103429,1.2252005430134607,0.9402000549206043,-0.7942051683058742,2.162388458299299,-0.20037731236087014,0.8345684311908745,0.7989843584173286,-0.21423082748473318,-0.4832296221450455,-0.497702095159616,0.6059317074422123,-0.67395649066749,0.7272427947625875,0.030736330125996712,0.8227280921116075,-0.03639319191522044,0.9402000549206043,-0.7337987947728196,0.7272427947625875,0.0839486679282727,-0.022912048485096835,-0.5559189875116972,-0.10421946745368259,0.6668633638533525,1.2586056494763058,0.2797397641478118,0.7031565908693913,2.883156326889429,2.485734940942485,-0.15899286265091292,-0.35441582638841634,2.2686535200777507,-0.31204139030411787,-0.7942051683058742,-0.8093962635979561,1.5200844134010096,-0.8858981156239302,1.157891088460552,0.11039372225624319,2.354405332523084,-0.9167574127737401,-0.36860244967466754,0.7751560059742102,0.14986255217829011,0.6910807910791582,-0.26994204317439974,0.5936781351799993,0.678983077713463,2.7142915025133245,0.9634495159911116,-0.07700433730373651,0.21512157560145628,-0.07700433730373651,-0.20037731236087014,0.6910807910791582,0.7392533700796472,0.2668667355288736
3,040
Electron transport
16
44
3.170889
0.00152
O43169,Q9P0J0,Q6DKK2,P03886,O75306,O14949,Q86Y39,Q96CU9,O96000,O75438,O43676,Q9UDW1,Q96HE7,Q9H3N1,Q9BW72,Q9H1E5
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
0,290,258,195,481,37,135,102,265,300,82,20,445,346,380,30
964,37,0,1219,82,948,481,300,1104,487,1577,591,265,928,195,1283,2448,1224,2805,565,1201,819,3015,2168,1387,2759,2667,2633,1410,674,1785,1212,2025,258,135,102,445,380,30,346,861,290,20,1165
0.25396851053519315,2.8567608273079417,3.577057121137054,0.030736330125996712,2.335440450294008,0.2668667355288736,0.8817214834855824,1.3249255008810943,0.12357638308743593,0.8699643062088395,-0.22811391955386917,0.7031565908693913,1.444853358337915,0.2925877034989214,1.6576351441981245,-0.009458648363643903,-0.7187857872122325,0.030736330125996712,-1.0417117055833216,0.7392533700796472,0.04407999074490389,0.43228908847773645,-2.14215547799472,-0.5413153919519684,-0.09059771360529514,-0.9945658344832891,-0.9013091013207586,-0.8705242595411103,-0.10421946745368259,0.5936781351799993,-0.326135443565647,0.04407999074490389,-0.4543816604229582,1.466432896979965,1.9347852868226298,2.2205527471728286,0.9518348493105416,1.0899037872341268,2.926930843467107,1.2028384651163935,0.3818296309293903,1.3578437107911476,3.158748918172827,0.0839486679282727
3,040
Glycosylation
20
45
3.165186
0.00155
Q86YN1,O43505,Q96L58,Q86SQ9,O43909,Q9BV10,Q9BT22,Q9H0U3,P04062,P15291,O75503,Q6ZXV5,Q10471,Q9H9E3,P46977,Q9HC07,P04844,Q9BXS4,Q10472,O15118
Processes and pathways
GO Biological process
msigdb_gobp
3,383,390,134,525,149,154,427,180,564,190,320,600,612,348,97,228,363,237,255
2312,255,2494,383,525,1133,1182,2469,622,2192,190,2480,180,968,228,564,1460,348,2737,1702,1586,1411,600,237,2846,881,320,1153,134,3,1095,390,154,149,1063,363,427,1487,612,1177,97,2830,2335,1490,1050
-0.6294380842913514,1.466432896979965,-0.7639307486259913,1.0785056180895356,0.7989843584173286,0.09718452280470133,0.05739652070350504,-0.7337987947728196,0.6547215620472547,-0.5559189875116972,1.6785532275719157,-0.7488470548949705,1.7305705557513118,0.25396851053519315,1.5307642110055628,0.7392533700796472,-0.1452562941458644,1.1916296245752864,-0.9633282872250349,-0.28394483378593255,-0.22811391955386917,-0.10421946745368259,0.6910807910791582,1.509387857490035,-1.0892100749872293,0.3564547613061034,1.2586056494763058,0.0839486679282727,1.9347852868226298,3.577057121137054,0.13673262131565084,1.0670881313408322,1.8538258857549876,1.87415518169426,0.16296629013982664,1.1691560040620224,0.9866187689477497,-0.15899286265091292,0.678983077713463,0.07068604002806808,2.239833036702955,-1.0575050455050043,-0.6294380842913514,-0.15899286265091292,0.1760439488988051
3,040
calmodulin-related
7
13
3.152343
0.00162
O43852,Q8IYU8,Q14257,P80303,P0DP25,Q02818,P41208
Functions
Panther Protein class
panther_protein_class
352,356,165,36,72,282,31
352,72,1311,1147,31,1353,36,282,165,1139,356,680,495
1.180402160098838,2.3921809662769813,-0.03639319191522044,0.0839486679282727,2.9181976011109048,-0.06343920992511146,2.8655702953924993,1.3906030399301132,1.8027380962357773,0.09718452280470133,1.180402160098838,0.5936781351799993,0.8699643062088395
3,040
Carboxylic acid transport
20
31
3.139125
0.001695
P07602,Q9NZJ7,Q9H2D1,P28288,O60831,Q9UBX3,Q8N697,Q9H936,Q9Y619,P08195,Q15041,Q9UJS0,Q02978,O75915,Q8TDW0,Q9NP80,Q7L0J3,P04083,Q15042,P55011
Processes and pathways
GO Biological process
msigdb_gobp
266,138,21,659,184,62,836,717,81,842,601,621,745,742,378,111,369,373,631,630
184,1657,742,1052,373,1145,266,842,1222,2690,659,1148,913,996,630,745,601,631,882,2216,369,836,378,21,717,1116,111,138,62,621,81
1.720198637706239,-0.26994204317439974,0.5196783799645482,0.16296629013982664,1.112642456885775,0.0839486679282727,1.444853358337915,0.39448062923729826,0.030736330125996712,-0.9167574127737401,0.6059317074422123,0.0839486679282727,0.30541065998888134,0.21512157560145628,0.6425575843066014,0.5196783799645482,0.6910807910791582,0.6425575843066014,0.3564547613061034,-0.5559189875116972,1.135304704632808,0.40710747145539755,1.1012827099190845,3.1502967060450944,0.5567813080560997,0.12357638308743593,2.133122344403906,1.9347852868226298,2.495021804682221,0.6668633638533525,2.344929345274909
3,040
Abnormal retinal artery morphology
10
21
3.128967
0.001754
P03886,P07602,P17900,Q9NZJ7,Q9Y4P3,P10619,P00846,Q13510,P21964,P06865
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
195,266,169,138,206,84,22,54,86,246
2983,1850,22,195,246,266,1520,84,2482,294,169,86,1749,2048,2646,54,1912,1419,138,2789,206
-1.5849348762619273,-0.36860244967466754,3.0993713176235196,1.6576351441981245,1.4879442405996233,1.444853358337915,-0.18655323709370267,2.3259386091701724,-0.7488470548949705,1.3359159947113879,1.7821961261129045,2.3164237833166905,-0.31204139030411787,-0.46878952976590854,-0.8858981156239302,2.532046451483146,-0.39706930245536326,-0.10421946745368259,1.9347852868226298,-1.010242310415109,1.6050583254928277
3,040
Secondary active transmembrane transporter activity
18
21
3.128512
0.001757
Q8N697,Q9H936,P05141,Q02978,P12235,O95202,Q9UBX3,P51798,Q96ES6,P12236,P08195,O00400,P51790,O43826,Q15758,Q00325,Q8NE86,P55011
Functions
GO Molecular function
msigdb_gomf
836,717,387,745,172,488,62,844,178,143,842,51,723,405,882,536,801,630
51,405,488,387,842,172,143,1148,723,844,913,996,630,536,745,882,836,801,178,717,62
2.623760656175141,1.0327190479133637,0.8699643062088395,1.0670881313408322,0.39448062923729826,1.76159249707139,1.9045369603750726,0.0839486679282727,0.5444366893129593,0.39448062923729826,0.30541065998888134,0.21512157560145628,0.6425575843066014,0.7870808006365844,0.5196783799645482,0.3564547613061034,0.40710747145539755,0.45737527732568883,1.7409268040090475,0.5567813080560997,2.495021804682221
3,040
Phospholipid metabolism
27
49
3.106638
0.001892
Q8WUK0,Q96N66,P43304,Q9UG56,Q10713,Q8NF37,Q8IV08,Q08AM6,Q9BTU6,Q8NCC3,Q53H12,O14735,Q7L5N7,O95674,P40939,Q96PE3,Q9NUQ2,P61106,Q9NPH0,Q9NTJ5,Q86UL3,Q8NEB9,P48739,Q9NP80,Q9NQZ5,Q9HBU6,Q92604
Processes and pathways
Reactome Pathways
msigdb_reactome
396,269,629,144,279,411,158,161,546,423,422,804,693,551,688,849,205,845,80,471,750,105,744,111,113,513,769
1694,804,2445,551,2341,2042,1961,1426,688,1186,629,952,744,2550,845,1270,2907,161,279,1527,422,937,693,750,158,1234,423,105,411,1290,396,769,269,849,1440,1917,1944,859,546,1216,513,1047,111,80,113,471,205,1652,144
-0.28394483378593255,0.4448440621115383,-0.7187857872122325,0.7632098916182667,-0.6442432998834845,-0.46878952976590854,-0.4256619663333324,-0.1178697283777986,0.581401938827193,0.05739652070350504,0.6425575843066014,0.2668667355288736,0.5196783799645482,-0.7942051683058742,0.39448062923729826,0.003967132673760511,-1.2338789162429935,1.8129860846850323,1.40148779769058,-0.18655323709370267,0.9866187689477497,0.2925877034989214,0.581401938827193,0.5196783799645482,1.8334363171266495,0.030736330125996712,0.9866187689477497,2.1915315517867935,1.0097084148679092,-0.009458648363643903,1.055651255437339,0.49482734776906995,1.4340378681739008,0.39448062923729826,-0.1178697283777986,-0.39706930245536326,-0.4113498322372873,0.3818296309293903,0.7751560059742102,0.04407999074490389,0.8345684311908745,0.1760439488988051,2.133122344403906,2.344929345274909,2.1233394389583222,0.9051741409295114,1.6050583254928277,-0.25596938782450307,1.9045369603750726
3,040
Intrinsic component of golgi membrane
11
12
3.092391
0.001986
O15258,Q9Y5U9,O43505,P98194,Q9Y282,L0R6Q1,O15155,Q6ZRP7,O95070,Q9NRB3,Q8TB61
Localization
GO Cellular component
msigdb_gocc
382,328,383,503,39,263,334,498,117,478,251
263,334,382,383,117,503,600,498,251,478,39,328
1.444853358337915,1.2252005430134607,1.0785056180895356,1.0785056180895356,2.0840690101310213,0.8345684311908745,0.6910807910791582,0.8581864580997747,1.4771970637826917,0.8934580688928646,2.830266254288787,1.247488927312642
3,040
Parkinsons disease
14
50
3.09236
0.001986
P03886,O14949,P24539,O96000,P12235,P45880,Q9Y277,P12236,O43676,P14406,Q9UDW1,P00846,P21796,P13073
Processes and pathways
KEGG Pathways
msigdb_kegg
195,37,42,265,172,45,112,143,82,19,20,22,85,186
964,588,37,628,82,948,481,300,1104,974,487,1577,265,928,22,195,387,709,1283,2196,172,143,186,19,1224,2805,912,85,565,2867,819,42,2631,3015,2168,1387,797,45,2824,2633,1410,756,1639,2210,1785,1212,2981,20,112,1165
0.25396851053519315,0.7031565908693913,2.8567608273079417,0.6425575843066014,2.335440450294008,0.2668667355288736,0.8817214834855824,1.3249255008810943,0.12357638308743593,0.2410449813533824,0.8699643062088395,-0.22811391955386917,1.444853358337915,0.2925877034989214,3.0993713176235196,1.6576351441981245,1.0670881313408322,0.5567813080560997,-0.009458648363643903,-0.5559189875116972,1.76159249707139,1.9045369603750726,1.709810998068712,3.158748918172827,0.030736330125996712,-1.0417117055833216,0.30541065998888134,2.3164237833166905,0.7392533700796472,-1.153099610160616,0.43228908847773645,2.785886251994729,-0.8705242595411103,-2.14215547799472,-0.5413153919519684,-0.09059771360529514,0.45737527732568883,2.7142915025133245,-1.0575050455050043,-0.8705242595411103,-0.10421946745368259,0.5072645015459241,-0.25596938782450307,-0.5559189875116972,-0.326135443565647,0.04407999074490389,-1.5677651074261831,3.158748918172827,2.133122344403906,0.0839486679282727
3,040
Vacuolar membrane
41
127
3.090489
0.001998
P11279,P07602,Q9NZJ7,O60784,Q9Y6I9,Q14108,Q9UIQ6,P10253,Q8NF37,Q8IV08,Q14849,Q08AM6,P11117,Q9H0U3,Q9UEU0,P04062,P27105,Q15382,O75503,O95772,O15400,Q676U5,O15260,Q07065,Q96GC9,P42892,Q93050,Q86WC4,P10619,Q8N511,Q9Y487,Q8TCT8,Q8WTV0,Q9Y2T2,Q92542,Q9HC07,P04844,Q9BXS4,Q8NCG7,Q9HBH5,O15118
Localization
GO Cellular component
msigdb_gocc
261,266,138,268,15,272,276,400,411,158,32,161,288,427,437,180,181,309,190,193,439,66,448,196,79,208,210,83,84,213,91,220,221,222,349,97,228,363,234,377,255
1309,740,780,255,448,439,794,1984,1881,268,2445,2706,190,901,2388,590,193,2315,180,228,2408,266,2083,842,1959,1579,1034,400,84,288,2274,261,564,2664,993,2773,2867,181,1248,1459,773,1989,1460,1148,721,743,208,2587,995,1019,723,844,1124,690,450,1607,573,845,1056,2109,1561,2416,2050,196,161,2974,1909,1527,272,32,309,66,1191,3031,83,158,733,213,836,892,234,411,220,221,1396,1464,349,210,1465,1097,1466,1214,79,1708,696,734,2767,1944,546,363,1918,1308,427,2849,1710,637,1621,2291,377,97,1712,138,1651,1921,480,1549,437,1716,276,1472,1599,940,222,639,91,1342,15
-0.03639319191522044,0.5196783799645482,0.4698828319614009,1.466432896979965,0.9402000549206043,0.9518348493105416,0.45737527732568883,-0.4400058576962713,-0.3828202251674292,1.4340378681739008,-0.7187857872122325,-0.9322432477268474,1.6785532275719157,0.3182087393302986,-0.67395649066749,0.7031565908693913,1.6681021781961047,-0.6294380842913514,1.7305705557513118,1.5307642110055628,-0.6888648126817407,1.444853358337915,-0.497702095159616,0.39448062923729826,-0.4256619663333324,-0.22811391955386917,0.1760439488988051,1.0441949184190364,2.3259386091701724,1.3578437107911476,-0.599929555682314,1.455651681499925,0.7392533700796472,-0.9013091013207586,0.21512157560145628,-1.010242310415109,-1.153099610160616,1.7305705557513118,0.017365417996363004,-0.1452562941458644,0.4823668232401796,-0.4400058576962713,-0.1452562941458644,0.0839486679282727,0.5444366893129593,0.5196783799645482,1.594494252228917,-0.8246235312168924,0.21512157560145628,0.18909564139474644,0.5444366893129593,0.39448062923729826,0.11039372225624319,0.581401938827193,0.9402000549206043,-0.24202672664337113,0.7272427947625875,0.39448062923729826,0.16296629013982664,-0.5122071076002075,-0.21423082748473318,-0.6888648126817407,-0.46878952976590854,1.6471520721581714,1.8129860846850323,-1.516536577941719,-0.39706930245536326,-0.18655323709370267,1.4232051513701809,2.883156326889429,1.291846719852825,2.4671241214659725,0.05739652070350504,-4.288396656099267,2.335440450294008,1.8334363171266495,0.5320690778198703,1.583913814546594,0.40710747145539755,0.3309820465478143,1.5200844134010096,1.0097084148679092,1.5627036240741825,1.5627036240741825,-0.09059771360529514,-0.1452562941458644,1.1916296245752864,1.594494252228917,-0.1452562941458644,0.13673262131565084,-0.1452562941458644,0.04407999074490389,2.354405332523084,-0.28394483378593255,0.581401938827193,0.5320690778198703,-0.9945658344832891,-0.4113498322372873,0.7751560059742102,1.1691560040620224,-0.39706930245536326,-0.022912048485096835,0.9866187689477497,-1.0892100749872293,-0.28394483378593255,0.6425575843066014,-0.24202672664337113,-0.599929555682314,1.112642456885775,2.239833036702955,-0.28394483378593255,1.9347852868226298,-0.25596938782450307,-0.39706930245536326,0.8934580688928646,-0.20037731236087014,0.9634495159911116,-0.28394483378593255,1.4123551479690624,-0.1452562941458644,-0.22811391955386917,0.2925877034989214,1.5627036240741825,0.6425575843066014,2.28780100884114,-0.04990220374204181,3.309198170766442
3,040
Dementia
29
60
3.08534
0.002033
O43464,O60220,P07602,Q9NZJ7,Q14108,P00846,P61916,P35637,Q9UHD9,P17900,Q96RR1,P04350,Q96RL7,P04062,Q13510,P21912,P03886,O76024,O60313,O00429,Q9Y487,P22626,O96008,P04080,Q9NQZ5,P06865,Q9UBB4,P05067,O15118
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
628,264,266,138,272,22,410,289,558,169,556,672,696,180,54,565,195,323,455,468,91,473,489,613,113,246,638,126,255
468,255,628,700,264,455,2706,323,489,928,22,195,180,613,672,126,246,266,903,2611,169,1225,565,473,2665,843,2168,931,289,773,1989,2392,1203,2859,1637,1583,410,2208,2209,757,1391,54,272,1703,1332,1169,1234,985,986,2636,1708,696,556,2981,2125,113,138,638,558,91
0.9051741409295114,1.466432896979965,0.6425575843066014,0.5691030270776883,1.444853358337915,0.9285450565881448,-0.9322432477268474,1.247488927312642,0.8699643062088395,0.2925877034989214,3.0993713176235196,1.6576351441981245,1.7305705557513118,0.6668633638533525,0.5936781351799993,2.0048528443378144,1.4879442405996233,1.444853358337915,0.3182087393302986,-0.8551873385144706,1.7821961261129045,0.030736330125996712,0.7392533700796472,0.8934580688928646,-0.9013091013207586,0.39448062923729826,-0.5413153919519684,0.2925877034989214,1.3578437107911476,0.4823668232401796,-0.4400058576962713,-0.67395649066749,0.04407999074490389,-1.1370667422921092,-0.25596938782450307,-0.22811391955386917,1.0097084148679092,-0.5559189875116972,-0.5559189875116972,0.5072645015459241,-0.09059771360529514,2.532046451483146,1.4232051513701809,-0.28394483378593255,-0.04990220374204181,0.07068604002806808,0.030736330125996712,0.2280960394572554,0.2280960394572554,-0.8705242595411103,-0.28394483378593255,0.581401938827193,0.7632098916182667,-1.5677651074261831,-0.5122071076002075,2.1233394389583222,1.9347852868226298,0.6425575843066014,0.7632098916182667,2.28780100884114
3,040
Abnormality of head blood vessel
10
24
3.07834
0.002082
P03886,P07602,P17900,Q9NZJ7,Q9Y4P3,P10619,P00846,Q13510,P21964,P06865
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
195,266,169,138,206,84,22,54,86,246
1455,2983,1850,22,195,246,266,1520,84,2482,294,169,2690,86,1749,952,2048,2646,54,1912,1419,138,2789,206
-0.1452562941458644,-1.5849348762619273,-0.36860244967466754,3.0993713176235196,1.6576351441981245,1.4879442405996233,1.444853358337915,-0.18655323709370267,2.3259386091701724,-0.7488470548949705,1.3359159947113879,1.7821961261129045,-0.9167574127737401,2.3164237833166905,-0.31204139030411787,0.2668667355288736,-0.46878952976590854,-0.8858981156239302,2.532046451483146,-0.39706930245536326,-0.10421946745368259,1.9347852868226298,-1.010242310415109,1.6050583254928277
3,040
Azurophil granule
37
73
3.076971
0.002091
P11279,P07602,O00584,Q9NZJ7,O60784,P10253,Q9BTY2,P61916,Q8NF37,P08236,Q92820,P06280,Q9H0U3,P16278,P17900,P27105,Q13217,O00560,P15291,P53634,P15586,O15400,O15260,O43681,Q07065,P04066,O00754,Q9BRF8,P00387,P10619,O95721,Q9H7Z7,Q92542,P42785,Q13277,Q05655,P06865
Localization
GO Cellular component
msigdb_gocc
261,266,521,138,268,400,539,410,411,286,418,292,427,294,169,181,691,185,564,689,191,439,448,700,196,581,579,598,207,84,590,735,349,743,368,243,246
2443,740,185,521,579,448,439,700,268,2445,2706,590,207,581,292,246,2408,1033,266,1520,286,400,84,2725,261,564,191,294,169,181,2085,2368,1460,743,2019,2507,1504,995,1124,2203,689,1725,1583,1327,410,1152,1208,2845,2174,243,196,691,368,2713,1191,2308,411,349,418,1097,884,2593,1790,1944,598,539,2975,427,735,1714,138,1921,2467
-0.7187857872122325,0.5196783799645482,1.709810998068712,0.8108667616335737,0.7152105634749184,0.9402000549206043,0.9518348493105416,0.5691030270776883,1.4340378681739008,-0.7187857872122325,-0.9322432477268474,0.7031565908693913,1.594494252228917,0.7152105634749184,1.3468887104804244,1.4879442405996233,-0.6888648126817407,0.1760439488988051,1.444853358337915,-0.18655323709370267,1.368781057907327,1.0441949184190364,2.3259386091701724,-0.9477668055435992,1.455651681499925,0.7392533700796472,1.6785532275719157,1.3359159947113879,1.7821961261129045,1.7305705557513118,-0.497702095159616,-0.6590827110965932,-0.1452562941458644,0.5196783799645482,-0.4543816604229582,-0.7639307486259913,-0.172758465571682,0.21512157560145628,0.11039372225624319,-0.5559189875116972,0.581401938827193,-0.2979779017776956,-0.22811391955386917,-0.04990220374204181,1.0097084148679092,0.0839486679282727,0.04407999074490389,-1.0892100749872293,-0.5413153919519684,1.4986744858114172,1.6471520721581714,0.581401938827193,1.135304704632808,-0.9322432477268474,0.05739652070350504,-0.6146668929180736,1.0097084148679092,1.1916296245752864,0.9981735054914589,0.13673262131565084,0.3564547613061034,-0.8246235312168924,-0.326135443565647,-0.4113498322372873,0.7031565908693913,0.7870808006365844,-1.516536577941719,0.9866187689477497,0.5320690778198703,-0.28394483378593255,1.9347852868226298,-0.39706930245536326,-0.7187857872122325
3,040
Respiratory chain
12
30
3.073494
0.002116
Q9P0J0,O75306,Q6DKK2,P03886,O14949,Q86Y39,Q96CU9,O96000,O75438,O43676,Q9UDW1,Q9BW72
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
290,481,258,195,37,135,102,265,300,82,20,380
964,37,82,948,481,300,1104,487,1577,265,928,195,1283,1224,2805,819,3015,1387,2633,1410,1785,1212,258,135,102,380,861,290,20,1165
0.25396851053519315,2.8567608273079417,2.335440450294008,0.2668667355288736,0.8817214834855824,1.3249255008810943,0.12357638308743593,0.8699643062088395,-0.22811391955386917,1.444853358337915,0.2925877034989214,1.6576351441981245,-0.009458648363643903,0.030736330125996712,-1.0417117055833216,0.43228908847773645,-2.14215547799472,-0.09059771360529514,-0.8705242595411103,-0.10421946745368259,-0.326135443565647,0.04407999074490389,1.466432896979965,1.9347852868226298,2.2205527471728286,1.0899037872341268,0.3818296309293903,1.3578437107911476,3.158748918172827,0.0839486679282727
3,040
Membrane lipid catabolic process
10
12
3.061181
0.002205
Q9NXE4,P06280,Q99735,O95470,P17900,Q05655,P04062,P06865,Q13510,P50897
Processes and pathways
GO Biological process
msigdb_gobp
548,292,518,168,169,243,180,246,54,27
168,180,581,292,246,1520,169,27,243,54,518,548
1.7821961261129045,1.7305705557513118,0.7152105634749184,1.3468887104804244,1.4879442405996233,-0.18655323709370267,1.7821961261129045,2.979105090473296,1.4986744858114172,2.532046451483146,0.8227280921116075,0.7751560059742102
3,040
Golgi cisterna membrane
14
19
3.056599
0.002239
O00461,P98194,Q96L58,Q8NBN3,Q9Y6B6,P51572,Q15363,Q9Y3A3,Q99523,Q10472,Q10713,Q9H4A6,Q10471,P15291
Localization
GO Cellular component
msigdb_gocc
98,503,390,70,657,552,595,727,734,237,279,602,600,564
98,911,564,552,503,998,1411,600,237,279,595,70,1678,775,390,734,602,727,657
2.2301995822122382,0.30541065998888134,0.7392533700796472,0.7632098916182667,0.8345684311908745,0.21512157560145628,-0.10421946745368259,0.6910807910791582,1.509387857490035,1.40148779769058,0.7031565908693913,2.4297531039738196,-0.26994204317439974,0.4823668232401796,1.0670881313408322,0.5320690778198703,0.6910807910791582,0.5444366893129593,0.6181627463554006
3,040
SNARE protein
11
16
3.032608
0.002425
Q86Y82,P56962,O15400,O14653,O43752,Q9P2W9,Q13277,Q9UEU0,O15155,O95249,Q13190
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
506,450,439,454,108,46,368,437,334,343,319
2443,454,334,439,108,926,343,590,1124,450,319,368,506,46,437,1599
-0.7187857872122325,0.9285450565881448,1.2252005430134607,0.9518348493105416,2.162388458299299,0.2925877034989214,1.2028384651163935,0.7031565908693913,0.11039372225624319,0.9402000549206043,1.2586056494763058,1.135304704632808,0.8345684311908745,2.7142915025133245,0.9634495159911116,-0.22811391955386917
3,040
Sphingolipid biosynthetic process
10
16
3.03153
0.002433
Q9P035,Q96G23,Q99805,O95470,Q53H12,Q05655,P04062,O15269,Q13510,Q06136
Processes and pathways
GO Biological process
msigdb_gobp
224,133,425,168,422,243,180,431,54,278
924,431,719,168,180,1068,843,243,278,54,422,133,425,548,224,1921
0.2925877034989214,0.9634495159911116,0.5444366893129593,1.7821961261129045,1.7305705557513118,0.14986255217829011,0.39448062923729826,1.4986744858114172,1.40148779769058,2.532046451483146,0.9866187689477497,1.9448386266327375,0.9866187689477497,0.7751560059742102,1.5520737596319365,-0.39706930245536326
3,040
Snare complex
13
21
3.030785
0.002439
Q86Y82,P56962,O15400,O14653,O43752,Q9P2W9,Q13277,O75396,Q9UEU0,Q12981,O15155,O95249,Q13190
Localization
GO Cellular component
msigdb_gocc
506,450,439,454,108,46,368,527,437,209,334,343,319
2443,454,334,439,899,108,926,527,343,590,1124,1374,450,209,319,368,506,2767,46,437,1599
-0.7187857872122325,0.9285450565881448,1.2252005430134607,0.9518348493105416,0.3182087393302986,2.162388458299299,0.2925877034989214,0.7989843584173286,1.2028384651163935,0.7031565908693913,0.11039372225624319,-0.07700433730373651,0.9402000549206043,1.594494252228917,1.2586056494763058,1.135304704632808,0.8345684311908745,-0.9945658344832891,2.7142915025133245,0.9634495159911116,-0.22811391955386917
3,040
Slc mediated transmembrane transport
8
20
3.025961
0.002478
P05141,P12235,P12236,O00400,Q99808,Q8TB61,Q9UBX3,Q70HW3
Processes and pathways
Reactome Pathways
msigdb_reactome
387,172,143,51,316,251,62,61
51,387,842,878,172,143,1311,403,1090,996,630,882,2216,61,836,1072,251,316,717,62
2.623760656175141,1.0670881313408322,0.39448062923729826,0.3564547613061034,1.76159249707139,1.9045369603750726,-0.03639319191522044,1.0441949184190364,0.13673262131565084,0.21512157560145628,0.6425575843066014,0.3564547613061034,-0.5559189875116972,2.495021804682221,0.40710747145539755,0.14986255217829011,1.4771970637826917,1.269704145648055,0.5567813080560997,2.495021804682221
3,040
Sterol binding
9
17
3.003183
0.002672
Q14849,O95772,P35610,P45880,Q14108,Q96SU4,P21796,P61916,O15118
Functions
GO Molecular function
msigdb_gomf
32,193,582,45,272,245,85,410,255
255,875,589,193,2083,85,1068,1664,582,45,410,272,32,245,1683,1216,1596
1.466432896979965,0.3564547613061034,0.7031565908693913,1.6681021781961047,-0.497702095159616,2.3164237833166905,0.14986255217829011,-0.26994204317439974,0.7152105634749184,2.7142915025133245,1.0097084148679092,1.4232051513701809,2.883156326889429,1.4986744858114172,-0.26994204317439974,0.04407999074490389,-0.22811391955386917
3,040
Ion transport
87
197
3.000985
0.002691
P98194,Q9H4I9,Q9UDW1,Q9H2D1,P00846,Q00325,Q9C0H2,P24539,P45880,O00400,Q96PU5,O75844,Q9UBX3,Q70HW3,Q9HD47,P0DP25,O75964,Q96GC9,Q9Y619,Q86WC4,O14548,P21796,Q15041,Q9HC07,P56134,Q9UJS0,P78417,Q9NP80,Q9Y277,Q96S66,O15173,Q15042,P55011,P05067,Q15907,Q99623,Q9BVC6,P20020,Q9NZJ7,Q9UHG3,P12236,Q9UJZ1,P62942,P28288,Q9BPX6,P12235,Q96ES6,Q9HD20,Q08722,P27105,O60831,P13073,Q9UM00,O43681,Q9H936,P54709,P06576,Q8NE01,Q8N4V1,Q8TB61,Q13423,Q14728,Q9HC21,P07602,Q7KZN9,Q6NUK1,Q99808,O76024,P16615,P56385,Q8IYU8,Q7L0J3,P04083,Q8TDW0,P05141,Q6P4A7,O43826,O43808,Q9H0U3,Q96HE7,Q9P246,P54105,O00429,O96008,O95202,O75027,P05023
Processes and pathways
GO Biological process
msigdb_gobp
503,7,20,21,22,536,41,42,45,51,568,59,62,61,71,72,77,79,81,83,588,85,601,97,606,621,106,111,112,626,114,631,630,126,129,646,647,642,138,142,143,671,157,659,680,172,178,179,177,181,184,186,706,700,717,710,709,223,247,251,249,256,260,266,280,306,316,323,336,344,356,369,373,378,387,395,405,414,427,445,446,442,468,489,488,486,496
2443,2543,51,468,964,588,815,114,700,1367,925,414,405,1345,2597,184,486,2687,948,1265,1851,1497,1657,59,742,974,77,323,488,1052,2522,489,928,22,865,373,1221,496,126,387,1145,709,2408,2409,266,2083,818,842,1283,911,72,2196,878,1960,1009,172,143,186,1184,1222,336,2524,2411,642,912,993,2773,3010,2690,85,42,1323,2631,181,2471,659,2916,1311,1387,1459,1108,2759,797,773,1989,1148,2392,45,2587,1700,2824,1312,723,844,1124,913,996,442,710,630,606,344,1269,1056,2205,976,915,157,106,503,536,1908,2416,1812,745,933,757,2372,2738,177,2974,249,2456,2811,1752,256,1704,601,631,2073,882,129,1212,3012,306,2216,395,1375,61,280,369,83,1565,356,247,836,892,223,801,1072,251,378,178,79,445,568,626,2981,646,316,1873,680,1595,647,41,1378,427,1893,21,2538,7,717,1116,97,260,179,71,111,138,446,62,20,1490,142,1716,621,671,2033,706,2359,1261,112,1120,1770,1575,81,1829
-0.7187857872122325,-0.7942051683058742,2.623760656175141,0.9051741409295114,0.25396851053519315,0.7031565908693913,0.43228908847773645,2.103732071785902,0.5691030270776883,-0.07700433730373651,0.2925877034989214,0.9981735054914589,1.0327190479133637,-0.06343920992511146,-0.8398871595532866,1.720198637706239,0.8699643062088395,-0.9167574127737401,0.2668667355288736,0.003967132673760511,-0.36860244967466754,-0.172758465571682,-0.26994204317439974,2.5042963521150807,0.5196783799645482,0.2410449813533824,2.354405332523084,1.247488927312642,0.8699643062088395,0.16296629013982664,-0.7790500584504968,0.8699643062088395,0.2925877034989214,3.0993713176235196,0.3691543755103429,1.112642456885775,0.030736330125996712,0.8581864580997747,2.0048528443378144,1.0670881313408322,0.0839486679282727,0.5567813080560997,-0.6888648126817407,-0.6888648126817407,1.444853358337915,-0.497702095159616,0.43228908847773645,0.39448062923729826,-0.009458648363643903,0.30541065998888134,2.3921809662769813,-0.5559189875116972,0.3564547613061034,-0.4256619663333324,0.2021214798149985,1.76159249707139,1.9045369603750726,1.709810998068712,0.05739652070350504,0.030736330125996712,1.2252005430134607,-0.7790500584504968,-0.6888648126817407,0.6303713421013281,0.30541065998888134,0.21512157560145628,-1.010242310415109,-1.9751564924160614,-0.9167574127737401,2.3164237833166905,2.785886251994729,-0.04990220374204181,-0.8705242595411103,1.7305705557513118,-0.7337987947728196,0.6059317074422123,-1.2664819236308702,-0.03639319191522044,-0.09059771360529514,-0.1452562941458644,0.12357638308743593,-0.9945658344832891,0.45737527732568883,0.4823668232401796,-0.4400058576962713,0.0839486679282727,-0.67395649066749,2.7142915025133245,-0.8246235312168924,-0.28394483378593255,-1.0575050455050043,-0.03639319191522044,0.5444366893129593,0.39448062923729826,0.11039372225624319,0.30541065998888134,0.21512157560145628,0.9518348493105416,0.5567813080560997,0.6425575843066014,0.678983077713463,1.2028384651163935,0.003967132673760511,0.16296629013982664,-0.5559189875116972,0.2410449813533824,0.30541065998888134,1.8334363171266495,2.181830786620961,0.8345684311908745,0.7870808006365844,-0.39706930245536326,-0.6888648126817407,-0.34026020681916364,0.5196783799645482,0.2925877034989214,0.5072645015459241,-0.6590827110965932,-0.9633282872250349,1.7409268040090475,-1.516536577941719,1.4771970637826917,-0.7187857872122325,-1.0417117055833216,-0.31204139030411787,1.466432896979965,-0.28394483378593255,0.6910807910791582,0.6425575843066014,-0.4832296221450455,0.3564547613061034,1.9749109921081565,0.04407999074490389,-2.0673749691364636,1.302890926914009,-0.5559189875116972,1.055651255437339,-0.07700433730373651,2.495021804682221,1.40148779769058,1.135304704632808,2.335440450294008,-0.21423082748473318,1.180402160098838,1.4879442405996233,0.40710747145539755,0.3309820465478143,1.5520737596319365,0.45737527732568883,0.14986255217829011,1.4771970637826917,1.1012827099190845,1.7409268040090475,2.354405332523084,0.9518348493105416,0.7392533700796472,0.6547215620472547,-1.5677651074261831,0.6303713421013281,1.269704145648055,-0.36860244967466754,0.5936781351799993,-0.22811391955386917,0.6303713421013281,2.803671793152203,-0.07700433730373651,0.9866187689477497,-0.3828202251674292,3.1502967060450944,-0.7790500584504968,3.513034705457238,0.5567813080560997,0.12357638308743593,2.239833036702955,1.466432896979965,1.7409268040090475,2.4297531039738196,2.133122344403906,1.9347852868226298,0.9518348493105416,2.495021804682221,3.158748918172827,-0.15899286265091292,1.9146345006853838,-0.28394483378593255,0.6668633638533525,0.6059317074422123,-0.4543816604229582,0.5691030270776883,-0.6442432998834845,0.017365417996363004,2.133122344403906,0.12357638308743593,-0.31204139030411787,-0.21423082748473318,2.344929345274909,-0.34026020681916364
3,040
SNARE protein
11
17
3.000483
0.002696
Q86Y82,P56962,O15400,O14653,O43752,Q9P2W9,Q13277,Q9UEU0,O15155,O95249,Q13190
Functions
Panther Protein class
panther_protein_class
506,450,439,454,108,46,368,437,334,343,319
2443,454,334,439,108,926,343,590,1124,450,319,368,506,1820,46,437,1599
-0.7187857872122325,0.9285450565881448,1.2252005430134607,0.9518348493105416,2.162388458299299,0.2925877034989214,1.2028384651163935,0.7031565908693913,0.11039372225624319,0.9402000549206043,1.2586056494763058,1.135304704632808,0.8345684311908745,-0.34026020681916364,2.7142915025133245,0.9634495159911116,-0.22811391955386917
3,040
Oxidative phosphorylation
16
56
3.000062
0.002699
P03886,O14949,Q86Y39,P24539,O96000,O75438,O75964,Q93050,P14406,Q9UDW1,O43676,Q7KZN9,P00846,P56385,P13073,Q9Y487
Processes and pathways
KEGG Pathways
msigdb_kegg
195,37,135,42,265,300,77,210,19,20,82,280,22,344,186,91
964,588,37,82,948,481,300,1104,974,77,487,1577,265,928,22,195,709,1283,2196,186,19,1224,2805,912,993,2773,565,819,42,2631,3015,2168,1387,797,773,1989,2824,2633,1410,606,344,1056,2956,643,1785,1212,280,135,210,1620,20,1716,91,1342,1165,392
0.25396851053519315,0.7031565908693913,2.8567608273079417,2.335440450294008,0.2668667355288736,0.8817214834855824,1.3249255008810943,0.12357638308743593,0.2410449813533824,2.354405332523084,0.8699643062088395,-0.22811391955386917,1.444853358337915,0.2925877034989214,3.0993713176235196,1.6576351441981245,0.5567813080560997,-0.009458648363643903,-0.5559189875116972,1.709810998068712,3.158748918172827,0.030736330125996712,-1.0417117055833216,0.30541065998888134,0.21512157560145628,-1.010242310415109,0.7392533700796472,0.43228908847773645,2.785886251994729,-0.8705242595411103,-2.14215547799472,-0.5413153919519684,-0.09059771360529514,0.45737527732568883,0.4823668232401796,-0.4400058576962713,-1.0575050455050043,-0.8705242595411103,-0.10421946745368259,0.678983077713463,1.2028384651163935,0.16296629013982664,-1.3986061455300502,0.6303713421013281,-0.326135443565647,0.04407999074490389,1.40148779769058,1.9347852868226298,1.594494252228917,-0.24202672664337113,3.158748918172827,-0.28394483378593255,2.28780100884114,-0.04990220374204181,0.0839486679282727,1.0670881313408322
3,040
Mitochondrion organization
85
188
2.995534
0.00274
Q9NS69,Q8N4H5,Q99595,Q9Y2R0,O60830,P14406,Q9BSK2,P62072,P51572,P45880,Q5T9A4,O43615,Q9BUR5,O14925,Q9NVT9,Q9NVI7,Q99797,Q15070,Q9H061,Q9Y584,Q3ZCQ8,P0DP25,Q96A26,O43676,O14548,P21796,Q9H4A6,Q13505,O14965,Q96CU9,Q69YU5,Q9Y371,Q9NUQ9,Q5XKP0,O43464,Q99623,Q86Y39,Q9UG56,Q9UJZ1,Q8N8Q8,Q9Y6C9,O00165,Q9HAV7,Q9H3K2,P12235,Q96RL7,O14737,P04062,Q8IWA4,Q15388,Q96I36,O95429,P03886,Q9BWH2,Q5JRX3,Q9Y5J9,Q6DKK2,O60220,O96000,Q96E52,Q10713,Q9P0J0,O75153,P52789,O75438,Q9UDX5,Q16891,P55786,Q9BW72,P05141,Q9BUB7,O75880,P51530,Q9GZY8,Q53H12,P17152,Q9Y512,Q9UH62,O60313,O00429,O75306,O96008,O95202,O95168,Q9NX63
Processes and pathways
GO Biological process
msigdb_gobp
5,6,8,10,13,19,34,43,552,45,554,561,49,56,578,577,576,60,64,69,584,72,78,82,588,85,602,96,604,102,107,639,120,122,628,646,135,144,671,148,156,658,684,163,172,696,176,180,694,692,183,686,195,215,219,241,258,264,265,274,279,290,287,296,300,351,361,374,380,387,397,407,408,426,422,428,447,453,455,468,481,489,488,487,515
658,1309,468,588,176,56,604,628,561,82,795,264,455,13,910,287,3005,948,481,1265,707,300,1497,1104,1457,407,1500,796,487,488,1577,877,686,2082,754,265,489,2144,865,195,180,2643,929,387,1458,992,2770,72,2582,1107,172,19,428,2042,85,843,2471,3015,1779,2916,2318,2844,1185,1833,2727,2837,2392,45,1502,1227,1635,2413,755,2693,408,552,1410,296,1167,374,1607,43,1639,1231,1908,799,279,96,1614,60,1885,692,2654,1038,1785,1212,361,2878,584,422,219,1287,554,1059,122,107,258,916,3031,2182,2561,135,694,1155,1172,2218,2921,789,6,985,1817,148,801,838,1761,78,102,274,2461,183,1708,696,1316,2981,1790,8,646,2989,576,2058,1275,1595,34,2093,397,2893,49,850,380,215,1517,426,64,163,602,1024,684,751,5,120,718,577,578,861,1026,515,1241,290,1821,351,144,453,873,671,1654,10,1895,639,2097,1692,1382,1575,447,69,241,2641,156,1165
0.6059317074422123,-0.03639319191522044,0.9051741409295114,0.7031565908693913,1.7409268040090475,2.5228086401821996,0.678983077713463,0.6425575843066014,0.7512423742579706,2.335440450294008,0.45737527732568883,1.444853358337915,0.9285450565881448,3.3339674069724357,0.30541065998888134,1.3578437107911476,-1.9023594433529125,0.2668667355288736,0.8817214834855824,0.003967132673760511,0.5567813080560997,1.3249255008810943,-0.172758465571682,0.12357638308743593,-0.1452562941458644,1.0212235711320679,-0.172758465571682,0.45737527732568883,0.8699643062088395,0.8699643062088395,-0.22811391955386917,0.3564547613061034,0.581401938827193,-0.497702095159616,0.5072645015459241,1.444853358337915,0.8699643062088395,-0.5267448194609747,0.3691543755103429,1.6576351441981245,1.7305705557513118,-0.8858981156239302,0.2925877034989214,1.0670881313408322,-0.1452562941458644,0.21512157560145628,-1.010242310415109,2.3921809662769813,-0.8246235312168924,0.12357638308743593,1.76159249707139,3.158748918172827,0.97504413075297,-0.46878952976590854,2.3164237833166905,0.39448062923729826,-0.7337987947728196,-2.14215547799472,-0.326135443565647,-1.2664819236308702,-0.6294380842913514,-1.0892100749872293,0.05739652070350504,-0.35441582638841634,-0.9477668055435992,-1.073337763713145,-0.67395649066749,2.7142915025133245,-0.172758465571682,0.030736330125996712,-0.25596938782450307,-0.6888648126817407,0.5072645015459241,-0.9167574127737401,1.0212235711320679,0.7632098916182667,-0.10421946745368259,1.3359159947113879,0.07068604002806808,1.112642456885775,-0.24202672664337113,2.785886251994729,-0.25596938782450307,0.030736330125996712,-0.39706930245536326,0.45737527732568883,1.40148779769058,2.249453151058262,-0.24202672664337113,2.495021804682221,-0.3828202251674292,0.581401938827193,-0.8858981156239302,0.1760439488988051,-0.326135443565647,0.04407999074490389,1.1691560040620224,-1.169173172578633,0.7152105634749184,0.9866187689477497,1.5627036240741825,-0.009458648363643903,0.7632098916182667,0.16296629013982664,2.0445744152136456,2.181830786620961,1.466432896979965,0.30541065998888134,-4.288396656099267,-0.5413153919519684,-0.7942051683058742,1.9347852868226298,0.581401938827193,0.0839486679282727,0.07068604002806808,-0.5559189875116972,-1.2664819236308702,0.4698828319614009,3.513034705457238,0.2280960394572554,-0.34026020681916364,1.87415518169426,0.45737527732568883,0.40710747145539755,-0.31204139030411787,2.354405332523084,2.2205527471728286,1.4123551479690624,-0.7187857872122325,1.7305705557513118,-0.28394483378593255,0.581401938827193,-0.03639319191522044,-1.5677651074261831,-0.326135443565647,3.4808081262608535,0.6303713421013281,-1.6367289091365962,0.7272427947625875,-0.46878952976590854,0.003967132673760511,-0.22811391955386917,2.883156326889429,-0.497702095159616,1.055651255437339,-1.201443286855556,2.6510426426330733,0.39448062923729826,1.0899037872341268,1.583913814546594,-0.172758465571682,0.9866187689477497,2.4764357251667803,1.8129860846850323,0.6910807910791582,0.18909564139474644,0.5936781351799993,0.5196783799645482,3.553115528153787,2.0742164858122125,0.5567813080560997,0.7272427947625875,0.7272427947625875,0.3818296309293903,0.18909564139474644,0.8345684311908745,0.030736330125996712,1.3578437107911476,-0.34026020681916364,1.1916296245752864,1.9045369603750726,0.9402000549206043,0.3691543755103429,0.6059317074422123,-0.25596938782450307,3.432195062095224,-0.3828202251674292,0.6425575843066014,-0.497702095159616,-0.26994204317439974,-0.07700433730373651,-0.21423082748473318,0.9518348493105416,2.4391146215009063,1.509387857490035,-0.8705242595411103,1.843638659880809,0.0839486679282727
3,040
Transport vesicle membrane
20
46
2.98166
0.002867
Q86Y82,Q15907,P20020,P49755,O75396,Q9NR31,Q9UEU0,P04439,Q9Y3B3,Q13190,P56962,O76024,P0DP25,O14653,Q15363,O00429,O43760,P10321,O43752,Q7L0J3
Localization
GO Cellular component
msigdb_gocc
506,129,642,517,527,285,437,562,570,319,450,323,72,454,595,468,88,605,108,369
468,454,863,753,1984,108,88,926,1538,2192,527,323,1658,1745,1807,2315,1958,562,1034,1776,72,605,809,642,1961,1227,517,1019,1124,2048,450,1428,1151,2416,319,595,2114,129,369,506,285,1536,437,570,657,963
0.9051741409295114,0.9285450565881448,0.3691543755103429,0.5072645015459241,-0.4400058576962713,2.162388458299299,2.306895933969297,0.2925877034989214,-0.20037731236087014,-0.5559189875116972,0.7989843584173286,1.247488927312642,-0.26994204317439974,-0.31204139030411787,-0.34026020681916364,-0.6294380842913514,-0.4256619663333324,0.7512423742579706,0.1760439488988051,-0.326135443565647,2.3921809662769813,0.678983077713463,0.4448440621115383,0.6303713421013281,-0.4256619663333324,0.030736330125996712,0.8227280921116075,0.18909564139474644,0.11039372225624319,-0.46878952976590854,0.9402000549206043,-0.1178697283777986,0.0839486679282727,-0.6888648126817407,1.2586056494763058,0.7031565908693913,-0.5122071076002075,1.9749109921081565,1.135304704632808,0.8345684311908745,1.37970081375604,-0.18655323709370267,0.9634495159911116,0.7392533700796472,0.6181627463554006,0.2668667355288736
3,040
Macromolecule transmembrane transporter activity
8
14
2.977623
0.002905
Q9NS69,Q9UGP8,Q9Y584,Q99595,Q07820,O96008,O60830,O14925
Functions
GO Molecular function
msigdb_gomf
5,520,69,8,456,489,13,56
56,13,1500,489,517,784,976,456,692,836,8,5,520,69
2.5228086401821996,3.3339674069724357,-0.172758465571682,0.8699643062088395,0.8227280921116075,0.4698828319614009,0.2410449813533824,0.9285450565881448,0.581401938827193,0.40710747145539755,3.4808081262608535,3.553115528153787,0.8227280921116075,2.4391146215009063
3,040
Abnormal biliary tract morphology
8
22
2.977381
0.002907
P07602,P09601,Q9NZJ7,Q14108,P04062,Q10713,Q14739,Q5XKP0
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
266,9,138,272,180,279,116,122
700,2144,180,266,9,1222,2150,1833,755,1427,279,1092,272,116,122,1940,938,2267,138,370,1654,2227
0.5691030270776883,-0.5267448194609747,1.7305705557513118,1.444853358337915,3.464640376876938,0.030736330125996712,-0.5267448194609747,-0.35441582638841634,0.5072645015459241,-0.1178697283777986,1.40148779769058,0.13673262131565084,1.4232051513701809,2.0939075243292486,2.0445744152136456,-0.4113498322372873,0.2925877034989214,-0.5852259038097922,1.9347852868226298,1.135304704632808,-0.25596938782450307,-0.5559189875116972
3,040
Corneal opacity
23
51
2.972763
0.002951
O43505,Q5H8A4,O60566,Q06136,Q15645,P08236,Q08AM6,P06280,P16278,P53701,Q6NUK1,P04062,Q13510,P51648,O75844,Q9NVI7,O75381,P04066,Q9Y4P3,P10619,P40855,O95202,Q9Y5Y5
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
383,130,526,278,537,286,161,292,294,421,306,180,54,57,59,577,318,581,206,84,229,488,516
579,1455,1264,383,1537,2683,1850,526,2875,318,729,59,1924,488,708,2144,180,581,292,286,2317,84,294,1135,1749,229,755,57,2202,421,1637,2646,2907,2890,278,161,1358,54,1912,537,2489,130,306,1177,577,861,1653,2789,1847,206,516
0.7152105634749184,-0.1452562941458644,0.003967132673760511,1.0785056180895356,-0.20037731236087014,-0.9167574127737401,-0.36860244967466754,0.7989843584173286,-1.169173172578633,1.2586056494763058,0.5320690778198703,2.5042963521150807,-0.4113498322372873,0.8699643062088395,0.5567813080560997,-0.5267448194609747,1.7305705557513118,0.7152105634749184,1.3468887104804244,1.368781057907327,-0.6294380842913514,2.3259386091701724,1.3359159947113879,0.09718452280470133,-0.31204139030411787,1.5307642110055628,0.5072645015459241,2.513558618811099,-0.5559189875116972,0.9866187689477497,-0.25596938782450307,-0.8858981156239302,-1.2338789162429935,-1.201443286855556,1.40148779769058,1.8129860846850323,-0.06343920992511146,2.532046451483146,-0.39706930245536326,0.7870808006365844,-0.7488470548949705,1.9749109921081565,1.302890926914009,0.07068604002806808,0.7272427947625875,0.3818296309293903,-0.25596938782450307,-1.010242310415109,-0.35441582638841634,1.6050583254928277,0.8345684311908745
3,040
Lipoprotein metabolic process
10
22
2.965002
0.003027
Q92643,Q5H8A4,Q676U5,Q8NEB9,Q9BQE5,O60762,Q9NUJ1,Q96S52,P04062,P50897
Processes and pathways
GO Biological process
msigdb_gobp
608,130,66,105,11,622,305,625,180,27
852,622,910,1804,877,180,2318,27,631,130,1287,66,978,105,608,1042,625,11,1741,971,305,1382
0.3818296309293903,0.6547215620472547,0.30541065998888134,-0.34026020681916364,0.3564547613061034,1.7305705557513118,-0.6294380842913514,2.979105090473296,0.6425575843066014,1.9749109921081565,-0.009458648363643903,2.4671241214659725,0.2410449813533824,2.1915315517867935,0.678983077713463,0.1760439488988051,0.6547215620472547,3.3914306381259736,-0.2979779017776956,0.25396851053519315,1.313917166044911,-0.07700433730373651
3,040
Protein transmembrane transporter activity
8
12
2.960948
0.003067
Q9NS69,Q9UGP8,Q9Y584,Q99595,Q07820,O96008,O60830,O14925
Functions
GO Molecular function
msigdb_gomf
5,520,69,8,456,489,13,56
56,13,1500,489,517,976,456,692,8,5,520,69
2.5228086401821996,3.3339674069724357,-0.172758465571682,0.8699643062088395,0.8227280921116075,0.2410449813533824,0.9285450565881448,0.581401938827193,3.4808081262608535,3.553115528153787,0.8227280921116075,2.4391146215009063
3,040
Mitochondrial calcium ion transport
9
16
2.95108
0.003167
Q99623,Q8IYU8,Q9H4I9,O95202,P45880,Q9Y277,Q9UJZ1,Q10713,P21796
Processes and pathways
Reactome Pathways
msigdb_reactome
646,356,7,488,45,112,671,279,85
1497,488,85,1185,45,279,356,801,1680,1316,646,680,7,671,112,1575
-0.172758465571682,0.8699643062088395,2.3164237833166905,0.05739652070350504,2.7142915025133245,1.40148779769058,1.180402160098838,0.45737527732568883,-0.26994204317439974,-0.03639319191522044,0.6303713421013281,0.5936781351799993,3.513034705457238,0.6059317074422123,2.133122344403906,-0.21423082748473318
3,040
primary active transporter
15
22
2.943932
0.003241
Q9BUN8,Q9HAV7,P98194,O60888,Q9NS69,Q8N4H5,P20020,Q6P4A7,O96008,P16615,P05023,O43826,Q15388,Q96B49,O75381
Functions
Panther Protein class
panther_protein_class
128,684,503,164,5,6,642,395,489,336,496,405,692,28,318
405,164,318,1500,489,496,2958,2498,336,642,710,503,692,882,395,6,892,28,128,1116,684,5
1.0327190479133637,1.8027380962357773,1.2586056494763058,-0.172758465571682,0.8699643062088395,0.8581864580997747,-1.4153183707260697,-0.7639307486259913,1.2252005430134607,0.6303713421013281,0.5567813080560997,0.8345684311908745,0.581401938827193,0.3564547613061034,1.055651255437339,3.513034705457238,0.3309820465478143,2.970436049511284,1.994886652159444,0.12357638308743593,0.5936781351799993,3.553115528153787
3,040
Mitochondrial complex iv assembly
6
13
2.941477
0.003267
Q9Y2R0,P14406,Q8N8Q8,Q7KZN9,Q96I36,P13073
Processes and pathways
WikiPathways
msigdb_wp
10,19,148,280,183,186
964,795,928,2196,186,19,912,280,148,183,1595,10,392
0.25396851053519315,0.45737527732568883,0.2925877034989214,-0.5559189875116972,1.709810998068712,3.158748918172827,0.30541065998888134,1.40148779769058,1.87415518169426,1.7305705557513118,-0.22811391955386917,3.432195062095224,1.0670881313408322
3,040
Intracellular protein transmembrane transport
15
21
2.940162
0.00328
Q9HAV7,Q9UGP8,Q3ZCQ8,Q99595,O96008,O60830,O43615,Q99442,Q15388,Q9Y5Y5,O14925,P50542,O95831,Q15629,O75381
Processes and pathways
GO Biological process
msigdb_gobp
684,520,584,8,489,13,561,509,692,516,56,755,754,125,318
56,561,13,318,1500,754,489,2582,772,755,1461,2279,976,692,125,584,509,8,684,520,516
2.5228086401821996,0.7512423742579706,3.3339674069724357,1.2586056494763058,-0.172758465571682,0.5072645015459241,0.8699643062088395,-0.8246235312168924,0.4823668232401796,0.5072645015459241,-0.1452562941458644,-0.599929555682314,0.2410449813533824,0.581401938827193,2.024742179505935,0.7152105634749184,0.8345684311908745,3.4808081262608535,0.5936781351799993,0.8227280921116075,0.8345684311908745
3,040
Nadh dehydrogenase complex assembly
10
26
2.93851
0.003298
Q9P0J0,Q9H061,O75306,P03886,Q96CU9,Q86Y39,O96000,O75438,O43676,Q15070
Processes and pathways
GO Biological process
msigdb_gobp
290,64,481,195,102,135,265,300,82,60
82,948,481,300,1104,487,1577,265,195,3015,1410,60,1785,1212,135,789,102,2093,64,1024,861,1241,290,1654,2097,1165
2.335440450294008,0.2668667355288736,0.8817214834855824,1.3249255008810943,0.12357638308743593,0.8699643062088395,-0.22811391955386917,1.444853358337915,1.6576351441981245,-2.14215547799472,-0.10421946745368259,2.495021804682221,-0.326135443565647,0.04407999074490389,1.9347852868226298,0.4698828319614009,2.2205527471728286,-0.497702095159616,2.4764357251667803,0.18909564139474644,0.3818296309293903,0.030736330125996712,1.3578437107911476,-0.25596938782450307,-0.497702095159616,0.0839486679282727
3,040
Oxidative phosphorylation
14
60
2.929024
0.0034
Q9BSK2,Q9H3K2,P03886,O14949,P24539,O96000,O75438,O75964,O43676,P14406,Q9UDW1,Q7KZN9,P00846,P13073
Processes and pathways
GO Biological process
msigdb_gobp
34,163,195,37,42,265,300,77,82,19,20,280,22,186
964,588,37,82,948,481,1265,300,1104,974,77,487,1577,265,928,22,195,1556,709,1283,1106,2196,186,19,1223,1224,2805,912,819,42,2631,950,3015,2916,2168,1387,1284,797,1325,2824,2633,1410,1583,606,344,2205,1785,1212,2262,280,2330,2981,1275,34,1893,163,20,671,2097,1165
0.25396851053519315,0.7031565908693913,2.8567608273079417,2.335440450294008,0.2668667355288736,0.8817214834855824,0.003967132673760511,1.3249255008810943,0.12357638308743593,0.2410449813533824,2.354405332523084,0.8699643062088395,-0.22811391955386917,1.444853358337915,0.2925877034989214,3.0993713176235196,1.6576351441981245,-0.21423082748473318,0.5567813080560997,-0.009458648363643903,0.12357638308743593,-0.5559189875116972,1.709810998068712,3.158748918172827,0.030736330125996712,0.030736330125996712,-1.0417117055833216,0.30541065998888134,0.43228908847773645,2.785886251994729,-0.8705242595411103,0.2668667355288736,-2.14215547799472,-1.2664819236308702,-0.5413153919519684,-0.09059771360529514,-0.009458648363643903,0.45737527732568883,-0.04990220374204181,-1.0575050455050043,-0.8705242595411103,-0.10421946745368259,-0.22811391955386917,0.678983077713463,1.2028384651163935,-0.5559189875116972,-0.326135443565647,0.04407999074490389,-0.5852259038097922,1.40148779769058,-0.6294380842913514,-1.5677651074261831,0.003967132673760511,2.883156326889429,-0.3828202251674292,1.8129860846850323,3.158748918172827,0.6059317074422123,-0.497702095159616,0.0839486679282727
3,040
Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins
22
61
2.91174
0.003594
Q86Y39,Q9Y6N1,O96000,Q8N8Q8,Q9UDW1,P00846,O75880,Q9P0J0,O14949,P24539,O75438,P21912,Q96I36,P13073,P03886,O75964,O43676,O14548,P56385,O75306,Q9NPL8,O95168
Processes and pathways
Reactome Pathways
msigdb_reactome
135,392,265,148,20,22,407,290,37,42,300,565,183,186,195,77,82,588,344,481,484,487
964,588,37,82,795,948,481,300,1104,407,974,77,487,1577,265,928,22,195,709,1283,2196,186,2448,1224,2805,912,565,819,42,2631,3015,2168,1387,797,2667,1780,2824,2633,1410,606,344,1671,674,1785,1212,135,789,148,183,1377,1595,2093,1024,484,861,1241,290,20,2097,1165,392
0.25396851053519315,0.7031565908693913,2.8567608273079417,2.335440450294008,0.45737527732568883,0.2668667355288736,0.8817214834855824,1.3249255008810943,0.12357638308743593,1.0212235711320679,0.2410449813533824,2.354405332523084,0.8699643062088395,-0.22811391955386917,1.444853358337915,0.2925877034989214,3.0993713176235196,1.6576351441981245,0.5567813080560997,-0.009458648363643903,-0.5559189875116972,1.709810998068712,-0.7187857872122325,0.030736330125996712,-1.0417117055833216,0.30541065998888134,0.7392533700796472,0.43228908847773645,2.785886251994729,-0.8705242595411103,-2.14215547799472,-0.5413153919519684,-0.09059771360529514,0.45737527732568883,-0.9013091013207586,-0.326135443565647,-1.0575050455050043,-0.8705242595411103,-0.10421946745368259,0.678983077713463,1.2028384651163935,-0.26994204317439974,0.5936781351799993,-0.326135443565647,0.04407999074490389,1.9347852868226298,0.4698828319614009,1.87415518169426,1.7305705557513118,-0.07700433730373651,-0.22811391955386917,-0.497702095159616,0.18909564139474644,0.8817214834855824,0.3818296309293903,0.030736330125996712,1.3578437107911476,3.158748918172827,-0.497702095159616,0.0839486679282727,1.0670881313408322
3,040
Transport of small molecules
64
147
2.909641
0.003618
Q9BUN8,Q99623,P98194,O15118,Q9H4I9,Q15904,P09601,P20020,Q9Y6B6,P05141,P12236,Q9UJZ1,P35613,Q10713,Q9UBV2,P61916,P28288,P63218,Q9BPX6,P30519,Q9H0U3,Q92530,P49721,Q9C0H2,P12235,P45880,O00231,Q9HD20,O00400,Q96PU5,P27105,P07237,P61289,P53680,Q9UBX3,Q70HW3,Q99797,Q99808,P25787,Q9UNS2,Q9H936,P35610,P28070,P54709,P16615,P10644,Q86WC4,Q93050,O94905,P21796,Q9Y487,Q8WTV0,P28072,Q8IYU8,P40855,O95202,O75027,Q9Y277,P05023,Q8N4V1,Q8TDW0,Q8TB61,P55011,Q9BU23
Processes and pathways
Reactome Pathways
msigdb_reactome
128,646,503,255,7,643,9,642,657,387,143,671,403,279,413,410,659,415,680,35,427,679,295,41,172,45,560,179,51,568,181,307,433,690,62,61,576,316,701,587,717,582,203,710,336,592,83,210,589,85,91,221,474,356,229,488,486,112,496,247,378,251,630,127
560,2607,51,1218,2820,255,1405,486,1497,875,1457,2895,589,2388,488,2315,865,496,387,1032,307,818,842,1034,9,592,878,172,143,1663,336,1925,642,2343,810,993,2773,1540,85,2808,701,1372,2298,181,2430,203,474,1557,659,35,1311,1185,582,2104,403,2868,1090,773,2988,1989,229,1522,45,1666,1010,295,1478,723,844,690,996,710,630,1727,1583,1352,433,1056,410,1230,1523,1836,2109,812,415,503,2861,2416,1357,279,1640,1525,2456,2811,2178,2179,882,643,2216,61,2355,83,356,247,836,892,2309,801,1072,251,378,221,679,1680,210,1466,568,1316,1943,2593,646,576,316,680,127,128,41,427,2538,7,717,179,3020,1119,413,62,1195,1716,671,822,1827,587,112,91,1575,1342,657
0.7512423742579706,-0.8551873385144706,2.623760656175141,0.030736330125996712,-1.0575050455050043,1.466432896979965,-0.10421946745368259,0.8699643062088395,-0.172758465571682,0.3564547613061034,-0.1452562941458644,-1.217640296483119,0.7031565908693913,-0.67395649066749,0.8699643062088395,-0.6294380842913514,0.3691543755103429,0.8581864580997747,1.0670881313408322,0.1760439488988051,1.291846719852825,0.43228908847773645,0.39448062923729826,0.1760439488988051,3.464640376876938,0.7031565908693913,0.3564547613061034,1.76159249707139,1.9045369603750726,-0.26994204317439974,1.2252005430134607,-0.4113498322372873,0.6303713421013281,-0.6442432998834845,0.4448440621115383,0.21512157560145628,-1.010242310415109,-0.20037731236087014,2.3164237833166905,-1.0417117055833216,0.5691030270776883,-0.07700433730373651,-0.6146668929180736,1.7305705557513118,-0.7038078525879563,1.615606089441541,0.8934580688928646,-0.21423082748473318,0.6059317074422123,2.874368785321353,-0.03639319191522044,0.05739652070350504,0.7152105634749184,-0.5122071076002075,1.0441949184190364,-1.153099610160616,0.13673262131565084,0.4823668232401796,-1.6367289091365962,-0.4400058576962713,1.5307642110055628,-0.18655323709370267,2.7142915025133245,-0.26994204317439974,0.2021214798149985,1.3359159947113879,-0.15899286265091292,0.5444366893129593,0.39448062923729826,0.581401938827193,0.21512157560145628,0.5567813080560997,0.6425575843066014,-0.2979779017776956,-0.22811391955386917,-0.06343920992511146,0.9634495159911116,0.16296629013982664,1.0097084148679092,0.030736330125996712,-0.18655323709370267,-0.35441582638841634,-0.5122071076002075,0.4448440621115383,0.9981735054914589,0.8345684311908745,-1.1370667422921092,-0.6888648126817407,-0.06343920992511146,1.40148779769058,-0.25596938782450307,-0.18655323709370267,-0.7187857872122325,-1.0417117055833216,-0.5413153919519684,-0.5413153919519684,0.3564547613061034,0.6303713421013281,-0.5559189875116972,2.495021804682221,-0.6442432998834845,2.335440450294008,1.180402160098838,1.4879442405996233,0.40710747145539755,0.3309820465478143,-0.6146668929180736,0.45737527732568883,0.14986255217829011,1.4771970637826917,1.1012827099190845,1.5627036240741825,0.5936781351799993,-0.26994204317439974,1.594494252228917,-0.1452562941458644,0.7392533700796472,-0.03639319191522044,-0.4113498322372873,-0.8246235312168924,0.6303713421013281,0.7272427947625875,1.269704145648055,0.5936781351799993,1.994886652159444,1.994886652159444,2.803671793152203,0.9866187689477497,-0.7790500584504968,3.513034705457238,0.5567813080560997,1.7409268040090475,-2.2560589488483793,0.12357638308743593,1.0097084148679092,2.495021804682221,0.05739652070350504,-0.28394483378593255,0.6059317074422123,0.43228908847773645,-0.34026020681916364,0.7152105634749184,2.133122344403906,2.28780100884114,-0.21423082748473318,-0.04990220374204181,0.6181627463554006
3,040
Endoplasmic reticulum tubular network
8
13
2.905105
0.003671
Q6NUK4,Q9NQC3,Q00765,Q8NHH9,Q9H2C2,P61026,P50402,Q9H6H4
Localization
GO Cellular component
msigdb_gocc
131,68,330,235,398,308,534,119
534,308,330,1640,1297,631,1484,131,235,398,119,921,68
0.7870808006365844,1.291846719852825,1.2363539137486759,-0.25596938782450307,-0.022912048485096835,0.6425575843066014,-0.15899286265091292,1.9749109921081565,1.5200844134010096,1.055651255437339,2.0742164858122125,0.30541065998888134,2.4391146215009063
3,040
Microbody membrane
15
25
2.902519
0.003702
Q8TB36,O43808,Q7Z434,P40855,O00116,Q9UKU0,Q9NP80,Q15067,O75192,Q9Y5Y5,P50542,Q8NBU5,P51648,P28288,O75381
Localization
GO Cellular component
msigdb_gocc
838,414,835,229,739,333,111,462,335,516,755,856,57,659,318
739,414,1066,335,318,941,1986,659,1018,229,755,57,1427,462,870,835,856,838,986,1533,1078,111,1193,333,516
0.5196783799645482,0.9981735054914589,0.14986255217829011,1.2252005430134607,1.2586056494763058,0.2797397641478118,-0.4400058576962713,0.6059317074422123,0.18909564139474644,1.5307642110055628,0.5072645015459241,2.513558618811099,-0.1178697283777986,0.9168697776340057,0.3691543755103429,0.40710747145539755,0.3818296309293903,0.40710747145539755,0.2280960394572554,-0.18655323709370267,0.14986255217829011,2.133122344403906,0.05739652070350504,1.2363539137486759,0.8345684311908745
3,040
Membrane protein complex
120
283
2.896446
0.003774
Q86Y82,Q9NS69,Q9UGP8,Q9H4I9,P49755,Q8N4H5,Q99595,O60830,O75396,P14406,Q9UDW1,P00846,Q9NPA0,O14949,Q9C0H2,P24539,P62072,P45880,Q9P2W9,Q9BUR5,P04439,Q9Y3B3,P21912,O14925,Q15005,Q9Y584,Q3ZCQ8,P0DP25,O75964,O43676,Q86WC4,O95721,O14548,P21796,Q15041,Q9Y487,Q13505,P10321,Q92643,P56134,Q96CU9,Q8NEB9,O43752,Q9Y277,Q96S52,Q96S66,Q5XKP0,Q8TCT9,O43464,Q9BUN8,Q99623,Q86Y39,Q15904,Q9Y6B6,P12236,P62942,Q9BPX6,Q08AM6,Q9HAV7,P12235,Q8IWA4,P67812,Q15388,P53680,O00560,P13073,O14579,Q9NVH1,P03886,P54709,P06576,O75431,Q07666,Q12981,Q93050,Q9UBU6,P49458,Q8N511,Q9Y2T2,Q9Y5M8,P04844,Q8N4V1,O96000,Q9NR31,Q9P0J0,O75438,Q9NR28,Q03518,P56378,Q13190,Q53GQ0,P51571,O15155,O95249,P56385,Q92542,P46977,Q8IYU8,Q16891,Q13277,Q8TDW0,P05141,Q9UBV2,P63218,Q9H0U3,Q53H12,Q9UEU0,O15269,Q15006,O94901,Q9Y512,O15400,P56962,O14653,Q9P253,O75306,O96008,O95168,P05023,Q9NX63
Localization
GO Cellular component
msigdb_gocc
506,5,520,7,517,6,8,13,527,19,20,22,541,37,41,42,43,45,46,49,562,570,565,56,574,69,584,72,77,82,83,590,588,85,601,91,96,605,608,606,102,105,108,112,625,626,122,124,628,128,646,135,643,657,143,157,680,161,684,172,694,182,692,690,185,186,187,718,195,710,709,707,711,209,210,211,722,213,222,227,228,247,265,285,290,300,311,312,315,319,324,329,334,343,344,349,348,356,361,368,378,387,413,415,427,422,437,431,434,432,447,439,450,454,480,481,489,487,496,515
2443,1309,2543,1694,964,185,588,187,780,454,991,56,37,1264,334,431,719,439,899,852,1954,628,794,82,1984,108,2684,926,1197,967,13,948,481,2192,527,707,2496,300,1104,974,901,77,1500,432,2388,1658,487,343,1577,1807,590,2315,265,489,928,22,1958,865,195,562,968,228,1221,496,387,1145,709,2408,842,1283,1579,2148,1034,1776,72,605,2196,2582,1425,172,143,186,19,2758,1224,1086,2805,912,993,2773,85,565,819,42,2631,2429,3015,2746,2916,2168,1387,1988,1108,1185,1123,797,773,1989,2727,1460,1148,2836,45,1700,348,2824,1541,820,722,517,2633,329,844,1124,1410,2601,2278,690,2048,710,1374,1583,1991,606,315,344,450,1461,1353,1055,1056,976,2737,2370,43,157,932,2109,1561,415,182,2416,312,1863,711,161,2974,209,2810,319,368,1782,96,2259,881,1432,1330,574,434,601,1254,2073,692,2114,643,1785,1212,361,584,324,422,788,1040,122,1191,916,83,135,506,694,356,978,6,247,213,837,2891,801,105,2657,1095,124,378,1396,1192,349,2244,608,1419,210,1042,1465,884,102,1466,871,1708,625,626,1917,8,646,2767,1515,1873,680,1236,128,49,41,427,2849,1710,1621,971,7,762,684,1712,541,311,285,5,718,2719,861,515,290,480,46,2940,1119,1550,211,413,1536,20,437,520,1048,1716,2594,1261,1599,2424,1654,112,940,222,2097,570,91,1575,447,69,1342,227,2963,1979,1217,1829,657,1165
-0.7187857872122325,-0.03639319191522044,-0.7942051683058742,-0.28394483378593255,0.25396851053519315,1.709810998068712,0.7031565908693913,1.6994075847691243,0.4698828319614009,0.9285450565881448,0.21512157560145628,2.5228086401821996,2.8567608273079417,0.003967132673760511,1.2252005430134607,0.9634495159911116,0.5444366893129593,0.9518348493105416,0.3182087393302986,0.3818296309293903,-0.4256619663333324,0.6425575843066014,0.45737527732568883,2.335440450294008,-0.4400058576962713,2.162388458299299,-0.9167574127737401,0.2925877034989214,0.04407999074490389,0.25396851053519315,3.3339674069724357,0.2668667355288736,0.8817214834855824,-0.5559189875116972,0.7989843584173286,0.5567813080560997,-0.7639307486259913,1.3249255008810943,0.12357638308743593,0.2410449813533824,0.3182087393302986,2.354405332523084,-0.172758465571682,0.9634495159911116,-0.67395649066749,-0.26994204317439974,0.8699643062088395,1.2028384651163935,-0.22811391955386917,-0.34026020681916364,0.7031565908693913,-0.6294380842913514,1.444853358337915,0.8699643062088395,0.2925877034989214,3.0993713176235196,-0.4256619663333324,0.3691543755103429,1.6576351441981245,0.7512423742579706,0.25396851053519315,1.5307642110055628,0.030736330125996712,0.8581864580997747,1.0670881313408322,0.0839486679282727,0.5567813080560997,-0.6888648126817407,0.39448062923729826,-0.009458648363643903,-0.22811391955386917,-0.5267448194609747,0.1760439488988051,-0.326135443565647,2.3921809662769813,0.678983077713463,-0.5559189875116972,-0.8246235312168924,-0.1178697283777986,1.76159249707139,1.9045369603750726,1.709810998068712,3.158748918172827,-0.9945658344832891,0.030736330125996712,0.13673262131565084,-1.0417117055833216,0.30541065998888134,0.21512157560145628,-1.010242310415109,2.3164237833166905,0.7392533700796472,0.43228908847773645,2.785886251994729,-0.8705242595411103,-0.7038078525879563,-2.14215547799472,-0.9789278954279232,-1.2664819236308702,-0.5413153919519684,-0.09059771360529514,-0.4400058576962713,0.12357638308743593,0.05739652070350504,0.11039372225624319,0.45737527732568883,0.4823668232401796,-0.4400058576962713,-0.9477668055435992,-0.1452562941458644,0.0839486679282727,-1.073337763713145,2.7142915025133245,-0.28394483378593255,1.1916296245752864,-1.0575050455050043,-0.20037731236087014,0.43228908847773645,0.5444366893129593,0.8227280921116075,-0.8705242595411103,1.2363539137486759,0.39448062923729826,0.11039372225624319,-0.10421946745368259,-0.8398871595532866,-0.599929555682314,0.581401938827193,-0.46878952976590854,0.5567813080560997,-0.07700433730373651,-0.22811391955386917,-0.4400058576962713,0.678983077713463,1.269704145648055,1.2028384651163935,0.9402000549206043,-0.1452562941458644,-0.06343920992511146,0.16296629013982664,0.16296629013982664,0.2410449813533824,-0.9633282872250349,-0.6590827110965932,2.785886251994729,1.8334363171266495,0.2925877034989214,-0.5122071076002075,-0.21423082748473318,0.9981735054914589,1.7305705557513118,-0.6888648126817407,1.2807844808764448,-0.36860244967466754,0.5567813080560997,1.8129860846850323,-1.516536577941719,1.594494252228917,-1.0417117055833216,1.2586056494763058,1.135304704632808,-0.326135443565647,2.249453151058262,-0.5852259038097922,0.3564547613061034,-0.1178697283777986,-0.04990220374204181,0.7272427947625875,0.9634495159911116,0.6910807910791582,0.017365417996363004,-0.4832296221450455,0.581401938827193,-0.5122071076002075,0.6303713421013281,-0.326135443565647,0.04407999074490389,1.1691560040620224,0.7152105634749184,1.247488927312642,0.9866187689477497,0.4698828319614009,0.1760439488988051,2.0445744152136456,0.05739652070350504,0.30541065998888134,2.335440450294008,1.9347852868226298,0.8345684311908745,0.581401938827193,1.180402160098838,0.2410449813533824,3.513034705457238,1.4879442405996233,1.583913814546594,0.40710747145539755,-1.201443286855556,0.45737527732568883,2.1915315517867935,-0.8858981156239302,0.13673262131565084,2.0445744152136456,1.1012827099190845,-0.09059771360529514,0.05739652070350504,1.1916296245752864,-0.5705557698197767,0.678983077713463,-0.10421946745368259,1.594494252228917,0.1760439488988051,-0.1452562941458644,0.3564547613061034,2.2205527471728286,-0.1452562941458644,0.3691543755103429,-0.28394483378593255,0.6547215620472547,0.6547215620472547,-0.39706930245536326,3.4808081262608535,0.6303713421013281,-0.9945658344832891,-0.172758465571682,-0.36860244967466754,0.5936781351799993,0.030736330125996712,1.994886652159444,2.6510426426330733,2.803671793152203,0.9866187689477497,-1.0892100749872293,-0.28394483378593255,-0.24202672664337113,0.25396851053519315,3.513034705457238,0.5072645015459241,0.5936781351799993,-0.28394483378593255,0.7870808006365844,1.291846719852825,1.37970081375604,3.553115528153787,0.5567813080560997,-0.9322432477268474,0.3818296309293903,0.8345684311908745,1.3578437107911476,0.8934580688928646,2.7142915025133245,-1.3321976873356531,0.12357638308743593,-0.20037731236087014,1.594494252228917,1.0097084148679092,-0.18655323709370267,3.158748918172827,0.9634495159911116,0.8227280921116075,0.1760439488988051,-0.28394483378593255,-0.8246235312168924,0.017365417996363004,-0.22811391955386917,-0.6888648126817407,-0.25596938782450307,2.133122344403906,0.2925877034989214,1.5627036240741825,-0.497702095159616,0.7392533700796472,2.28780100884114,-0.21423082748473318,0.9518348493105416,2.4391146215009063,-0.04990220374204181,1.541427307462825,-1.4488767491086494,-0.4256619663333324,0.04407999074490389,-0.34026020681916364,0.6181627463554006,0.0839486679282727
3,040
Monooxygenase activity
6
8
2.896107
0.003778
Q14534,P30519,P09601,Q15800,Q9BU89,Q6UW02
Functions
GO Molecular function
msigdb_gomf
194,35,9,109,47,53
9,35,1150,194,109,257,53,47
3.464640376876938,2.874368785321353,0.0839486679282727,1.6681021781961047,2.162388458299299,1.466432896979965,2.550485584113471,2.687254522059928
3,040
Outer mitochondrial membrane protein complex
12
16
2.892789
0.003818
Q13505,Q9NVH1,Q9NS69,Q8N4H5,O96008,Q16891,Q9BUR5,Q8IWA4,Q15388,Q9NX63,Q9Y512,Q5XKP0
Localization
GO Cellular component
msigdb_gocc
96,718,5,6,489,361,49,694,692,515,447,122
707,1500,489,2727,96,692,361,122,916,694,6,49,5,718,515,447
0.5567813080560997,-0.172758465571682,0.8699643062088395,-0.9477668055435992,2.249453151058262,0.581401938827193,1.1691560040620224,2.0445744152136456,0.30541065998888134,0.581401938827193,3.513034705457238,2.6510426426330733,3.553115528153787,0.5567813080560997,0.8345684311908745,0.9518348493105416
3,040
Glycerophospholipid biosynthesis
20
32
2.890997
0.00384
Q8WUK0,Q96N66,P43304,Q9UG56,Q8NF37,Q8IV08,Q8NCC3,Q53H12,O14735,Q7L5N7,O95674,P40939,Q9NUQ2,Q9NPH0,Q86UL3,P48739,Q9NP80,Q9NQZ5,Q9HBU6,Q92604
Processes and pathways
Reactome Pathways
msigdb_reactome
396,269,629,144,411,158,423,422,804,693,551,688,205,80,750,744,111,113,513,769
804,2445,551,2341,2042,1426,688,629,952,744,2550,1270,422,937,693,750,158,423,411,396,769,269,1944,859,1216,513,1047,111,80,113,205,144
0.4448440621115383,-0.7187857872122325,0.7632098916182667,-0.6442432998834845,-0.46878952976590854,-0.1178697283777986,0.581401938827193,0.6425575843066014,0.2668667355288736,0.5196783799645482,-0.7942051683058742,0.003967132673760511,0.9866187689477497,0.2925877034989214,0.581401938827193,0.5196783799645482,1.8334363171266495,0.9866187689477497,1.0097084148679092,1.055651255437339,0.49482734776906995,1.4340378681739008,-0.4113498322372873,0.3818296309293903,0.04407999074490389,0.8345684311908745,0.1760439488988051,2.133122344403906,2.344929345274909,2.1233394389583222,1.6050583254928277,1.9045369603750726
3,040
Cellular monovalent inorganic cation homeostasis
13
24
2.889797
0.003855
Q9HC07,Q15904,P54709,P06576,Q9Y487,P05023,Q93050,Q96PU5,Q8N511,P50897,Q92544,P55011,O75503
Processes and pathways
GO Biological process
msigdb_gobp
97,643,710,709,91,496,210,568,213,27,705,630,190
190,1745,496,709,911,2068,2085,27,1019,723,710,630,1056,643,213,705,210,1465,568,97,1490,1716,91,1829
1.6785532275719157,-0.31204139030411787,0.8581864580997747,0.5567813080560997,0.30541065998888134,-0.4832296221450455,-0.497702095159616,2.979105090473296,0.18909564139474644,0.5444366893129593,0.5567813080560997,0.6425575843066014,0.16296629013982664,0.6303713421013281,1.583913814546594,0.5691030270776883,1.594494252228917,-0.1452562941458644,0.7392533700796472,2.239833036702955,-0.15899286265091292,-0.28394483378593255,2.28780100884114,-0.34026020681916364
3,040
Endoplasmic reticulum tubular network organization
6
12
2.885162
0.003912
Q6NUK4,Q9NQC3,P57088,Q8NHH9,Q9H6H4,O95197
Processes and pathways
GO Biological process
msigdb_gobp
131,68,302,235,119,29
29,302,308,601,631,1484,131,235,1741,119,921,68
2.9356533136426415,1.3249255008810943,1.291846719852825,0.6910807910791582,0.6425575843066014,-0.15899286265091292,1.9749109921081565,1.5200844134010096,-0.2979779017776956,2.0742164858122125,0.30541065998888134,2.4391146215009063
3,040
Aminoglycan metabolic process
11
17
2.875659
0.004032
O43505,Q96L58,P16278,P54802,Q9NX62,P06865,Q8NCH0,Q9NRB3,P15586,P08236,Q7LGA3
Processes and pathways
GO Biological process
msigdb_gobp
383,390,294,384,467,246,55,478,191,286,95
383,2520,2315,581,246,1520,286,191,294,384,2416,1358,95,55,390,478,467
1.0785056180895356,-0.7790500584504968,-0.6294380842913514,0.7152105634749184,1.4879442405996233,-0.18655323709370267,1.368781057907327,1.6785532275719157,1.3359159947113879,1.0785056180895356,-0.6888648126817407,-0.06343920992511146,2.259059965503611,2.532046451483146,1.0670881313408322,0.8934580688928646,0.9168697776340057
3,040
Mitochondrial nucleotide transporter subfamily
8
9
2.874994
0.00404
Q9BSK2,Q9HC21,P05141,P12235,P12236,Q6NUK1,Q9H2D1,Q70HW3
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
34,260,387,172,143,306,21,61
414,387,172,143,306,61,34,21,260
0.9981735054914589,1.0670881313408322,1.76159249707139,1.9045369603750726,1.302890926914009,2.495021804682221,2.883156326889429,3.1502967060450944,1.466432896979965
3,040
Nuclear inner membrane
8
21
2.870747
0.004095
Q14728,Q99720,Q5SNT2,Q14739,O94901,Q8IXM6,O75844,Q9H1E5
Localization
GO Cellular component
msigdb_gocc
256,136,500,116,432,212,59,30
59,432,1225,1780,1203,534,1125,821,1209,1751,256,116,1672,500,212,2399,136,655,30,1048,1655
2.5042963521150807,0.9634495159911116,0.030736330125996712,-0.326135443565647,0.04407999074490389,0.7870808006365844,0.11039372225624319,0.43228908847773645,0.04407999074490389,-0.31204139030411787,1.466432896979965,2.0939075243292486,-0.26994204317439974,0.8463878597278127,1.583913814546594,-0.67395649066749,1.9347852868226298,0.6181627463554006,2.926930843467107,0.1760439488988051,-0.25596938782450307
3,040
Muscle abnormality related to mitochondrial dysfunction
14
37
2.862194
0.004207
O75306,P03886,Q96CU9,Q86Y39,O60313,Q9Y2R0,O96000,Q53H12,P12235,Q9NP80,O43676,P00846,P51530,Q9UBX3
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
481,195,102,135,455,10,265,422,172,111,82,22,408,62
964,82,455,948,481,1104,806,265,928,22,195,172,2805,3015,1780,2633,408,2257,422,135,789,1761,102,556,1595,2093,2893,1893,111,484,861,1241,62,10,1600,2097,1165
0.25396851053519315,2.335440450294008,0.9285450565881448,0.2668667355288736,0.8817214834855824,0.12357638308743593,0.4448440621115383,1.444853358337915,0.2925877034989214,3.0993713176235196,1.6576351441981245,1.76159249707139,-1.0417117055833216,-2.14215547799472,-0.326135443565647,-0.8705242595411103,1.0212235711320679,-0.5852259038097922,0.9866187689477497,1.9347852868226298,0.4698828319614009,-0.31204139030411787,2.2205527471728286,0.7632098916182667,-0.22811391955386917,-0.497702095159616,-1.201443286855556,-0.3828202251674292,2.133122344403906,0.8817214834855824,0.3818296309293903,0.030736330125996712,2.495021804682221,3.432195062095224,-0.22811391955386917,-0.497702095159616,0.0839486679282727
3,040
Cholesterol binding
8
14
2.860461
0.00423
Q14849,O95772,P35610,P45880,Q14108,P21796,P61916,O15118
Functions
GO Molecular function
msigdb_gomf
32,193,582,45,272,85,410,255
255,875,589,193,2083,85,1664,582,45,410,272,32,1216,1596
1.466432896979965,0.3564547613061034,0.7031565908693913,1.6681021781961047,-0.497702095159616,2.3164237833166905,-0.26994204317439974,0.7152105634749184,2.7142915025133245,1.0097084148679092,1.4232051513701809,2.883156326889429,0.04407999074490389,-0.22811391955386917
3,040
Nucleotide transmembrane transport
7
9
2.846326
0.004423
Q9BSK2,P05141,P12235,P12236,Q9H2D1,Q8TDW0,Q8TB61
Processes and pathways
GO Biological process
msigdb_gobp
34,387,172,143,21,378,251
414,387,172,143,1148,251,378,34,21
0.9981735054914589,1.0670881313408322,1.76159249707139,1.9045369603750726,0.0839486679282727,1.4771970637826917,1.1012827099190845,2.883156326889429,3.1502967060450944
3,040
Purine nucleotide transmembrane transporter activity
7
9
2.842106
0.004482
P05141,P12235,P12236,Q6NUK1,O00400,Q8TB61,Q99808
Functions
GO Molecular function
msigdb_gomf
387,172,143,306,51,251,316
51,414,387,172,143,1148,306,251,316
2.623760656175141,0.9981735054914589,1.0670881313408322,1.76159249707139,1.9045369603750726,0.0839486679282727,1.302890926914009,1.4771970637826917,1.269704145648055
3,040
Mitochondrial protein containing complex
47
154
2.810182
0.004951
Q9NS69,Q8N4H5,Q9H4I9,Q99595,Q86Y39,O60220,O96000,P05141,O60830,P12236,P14406,Q9UDW1,P00846,Q9P0J0,O14949,P24539,P62072,P12235,O75438,Q53H12,O60783,Q9BUR5,O14925,Q9Y512,P13073,P56378,Q567V2,P03886,Q9Y584,Q7Z7H8,O75964,O43676,P21796,O15091,P56385,Q13505,O75306,Q7Z7F7,Q8IYU8,Q96CU9,Q16891,O96008,O95168,Q9Y5J9,P82933,Q9NX63,Q5XKP0
Localization
GO Cellular component
msigdb_gocc
5,6,7,8,135,264,265,387,13,143,19,20,22,290,37,42,43,172,300,422,48,49,56,447,186,315,188,195,69,75,77,82,85,342,344,96,481,355,356,102,361,489,487,241,371,515,122
2386,1030,964,588,56,37,342,82,1406,264,48,13,948,481,707,300,1104,974,77,1499,1500,487,1577,265,489,928,22,195,387,709,2014,1283,2065,1106,2611,2196,1722,866,172,143,186,19,1224,2805,912,85,565,819,42,2631,3015,2916,2168,1387,1185,797,2727,688,2824,2200,2633,2548,1606,1410,1966,2257,2550,606,315,344,43,2350,1189,2487,954,2322,1069,1934,371,2258,96,2395,747,692,1058,1785,1212,361,584,422,188,122,800,916,1759,1256,355,75,135,694,2218,356,6,2848,801,1761,1074,1398,102,2184,2329,871,3037,8,646,2989,680,1001,49,1278,2185,1080,519,7,1422,684,1279,1238,1548,2186,5,718,1401,861,2249,515,1470,1688,290,20,1654,685,1691,1492,2097,1443,1953,1281,1575,447,69,241,2641,1165
-0.67395649066749,0.1760439488988051,0.25396851053519315,0.7031565908693913,2.5228086401821996,2.8567608273079417,1.2028384651163935,2.335440450294008,-0.10421946745368259,1.444853358337915,2.6691719156596547,3.3339674069724357,0.2668667355288736,0.8817214834855824,0.5567813080560997,1.3249255008810943,0.12357638308743593,0.2410449813533824,2.354405332523084,-0.172758465571682,-0.172758465571682,0.8699643062088395,-0.22811391955386917,1.444853358337915,0.8699643062088395,0.2925877034989214,3.0993713176235196,1.6576351441981245,1.0670881313408322,0.5567813080560997,-0.4543816604229582,-0.009458648363643903,-0.4832296221450455,0.12357638308743593,-0.8551873385144706,-0.5559189875116972,-0.2979779017776956,0.3691543755103429,1.76159249707139,1.9045369603750726,1.709810998068712,3.158748918172827,0.030736330125996712,-1.0417117055833216,0.30541065998888134,2.3164237833166905,0.7392533700796472,0.43228908847773645,2.785886251994729,-0.8705242595411103,-2.14215547799472,-1.2664819236308702,-0.5413153919519684,-0.09059771360529514,0.05739652070350504,0.45737527732568883,-0.9477668055435992,0.581401938827193,-1.0575050455050043,-0.5559189875116972,-0.8705242595411103,-0.7942051683058742,-0.24202672664337113,-0.10421946745368259,-0.4256619663333324,-0.5852259038097922,-0.7942051683058742,0.678983077713463,1.269704145648055,1.2028384651163935,2.785886251994729,-0.6442432998834845,0.05739652070350504,-0.7488470548949705,0.2668667355288736,-0.6294380842913514,0.14986255217829011,-0.4113498322372873,1.1239830984755548,-0.5852259038097922,2.249453151058262,-0.67395649066749,0.5196783799645482,0.581401938827193,0.16296629013982664,-0.326135443565647,0.04407999074490389,1.1691560040620224,0.7152105634749184,0.9866187689477497,1.6994075847691243,2.0445744152136456,0.45737527732568883,0.30541065998888134,-0.31204139030411787,0.017365417996363004,1.180402160098838,2.3733187365862856,1.9347852868226298,0.581401938827193,-0.5559189875116972,1.180402160098838,3.513034705457238,-1.0892100749872293,0.45737527732568883,-0.31204139030411787,0.14986255217829011,-0.09059771360529514,2.2205527471728286,-0.5413153919519684,-0.6294380842913514,0.3691543755103429,-7.192036564238519,3.4808081262608535,0.6303713421013281,-1.6367289091365962,0.5936781351799993,0.21512157560145628,2.6510426426330733,0.003967132673760511,-0.5413153919519684,0.14986255217829011,0.8227280921116075,3.513034705457238,-0.10421946745368259,0.5936781351799993,0.003967132673760511,0.030736330125996712,-0.20037731236087014,-0.5413153919519684,3.553115528153787,0.5567813080560997,-0.09059771360529514,0.3818296309293903,-0.5705557698197767,0.8345684311908745,-0.1452562941458644,-0.26994204317439974,1.3578437107911476,3.158748918172827,-0.25596938782450307,0.5936781351799993,-0.26994204317439974,-0.15899286265091292,-0.497702095159616,-0.1178697283777986,-0.4113498322372873,0.003967132673760511,-0.21423082748473318,0.9518348493105416,2.4391146215009063,1.509387857490035,-0.8705242595411103,0.0839486679282727
3,040
Central scotoma
7
11
2.809114
0.004968
Q9H061,P03886,O60220,Q9H6K4,O60313,O00429,P00846
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
64,195,264,167,455,468,22
468,264,455,481,796,22,195,1201,1870,64,167
0.9051741409295114,1.444853358337915,0.9285450565881448,0.8817214834855824,0.45737527732568883,3.0993713176235196,1.6576351441981245,0.04407999074490389,-0.36860244967466754,2.4764357251667803,1.79247479337959
3,040
Organic acid transport
28
44
2.797775
0.005146
P31751,P23786,Q6P4A7,Q9H2D1,P53007,P28288,O43808,O43772,P08183,O60831,Q9UBX3,Q8N697,P50416,Q9H936,Q9Y619,P08195,Q15041,Q9UJS0,Q02978,O75915,Q15758,Q9NP80,Q7L0J3,P11166,Q15042,P04083,Q8TDW0,P55011
Processes and pathways
GO Biological process
msigdb_gobp
772,140,395,21,913,659,414,925,818,184,62,836,583,717,81,842,601,621,745,742,882,111,369,878,631,373,378,630
925,414,184,1657,742,1052,941,2567,373,1145,2610,818,842,1853,878,1222,2690,140,659,1809,772,1018,1148,583,913,996,630,2845,745,601,631,882,2216,395,369,836,378,21,717,1116,111,62,621,81
0.2925877034989214,0.9981735054914589,1.720198637706239,-0.26994204317439974,0.5196783799645482,0.16296629013982664,0.2797397641478118,-0.8093962635979561,1.112642456885775,0.0839486679282727,-0.8551873385144706,0.43228908847773645,0.39448062923729826,-0.36860244967466754,0.3564547613061034,0.030736330125996712,-0.9167574127737401,1.9146345006853838,0.6059317074422123,-0.34026020681916364,0.4823668232401796,0.18909564139474644,0.0839486679282727,0.7152105634749184,0.30541065998888134,0.21512157560145628,0.6425575843066014,-1.0892100749872293,0.5196783799645482,0.6910807910791582,0.6425575843066014,0.3564547613061034,-0.5559189875116972,1.055651255437339,1.135304704632808,0.40710747145539755,1.1012827099190845,3.1502967060450944,0.5567813080560997,0.12357638308743593,2.133122344403906,2.495021804682221,0.6668633638533525,2.344929345274909
3,040
Golgi apparatus
69
178
2.795951
0.005175
Q86Y82,O75122,O15258,P98194,Q8IZA0,P49755,P09601,Q96RQ1,Q6NUQ1,Q9UG56,O95302,Q9NUJ3,Q02818,P50897,P40616,A1L0T0,P80303,P24390,P16278,Q9HD45,Q9NPR9,Q6ZU35,O00231,Q9UEU0,P04439,Q8NC54,P67812,Q8NCH0,P15291,O14579,Q9NWM8,Q13190,O15260,Q9UH62,Q8NBN3,Q92520,Q9HB40,O75071,O14653,O15127,Q9NX62,Q93050,Q9UBU6,Q6NUQ4,Q9NTJ5,Q10471,O43760,Q9H4A6,Q99640,Q92896,Q9NRB3,Q9HC07,O00461,Q5VW38,Q8IYS2,Q9NW68,Q9BRK5,Q8TBA6,O43752,Q8N4Q0,Q9NP80,Q6ZRP7,Q05655,O95070,Q96SU4,Q9H2V7,Q8TDW0,Q9H0U4,P05067
Localization
Protein Atlas Subcellular
protein_atlas_subcellular_location_all
506,501,382,503,132,517,9,267,652,144,277,670,282,27,661,159,36,38,294,170,557,44,560,437,562,52,182,55,564,187,317,319,448,453,70,199,73,322,454,76,467,210,211,341,471,600,88,602,217,609,478,97,98,101,618,514,495,364,108,365,111,498,243,117,245,637,378,510,126
159,728,1656,1309,560,98,187,454,1424,863,76,1103,382,448,2252,2337,1954,2138,781,108,88,1133,1066,926,1538,1384,322,501,2875,1539,901,1852,117,1745,277,1519,2341,562,126,2822,9,2866,1425,564,294,879,1068,38,2166,2584,2585,1749,1123,1090,661,2587,2069,1541,517,755,1312,2693,27,2549,2588,1167,2256,2601,2278,983,826,182,36,503,1430,282,243,998,1411,600,1909,319,1614,1286,944,3006,787,885,1287,1641,1674,101,2397,1191,984,652,341,1888,2117,498,1529,44,1843,1113,2355,2437,506,2573,2962,1593,2053,618,132,1736,365,1128,70,52,55,1072,704,364,1213,2157,378,199,1129,609,210,2892,1235,2574,2592,2438,267,245,734,1044,217,1873,2927,495,1260,1683,510,1919,637,1142,1846,602,683,1177,2291,1791,73,97,170,111,557,1623,478,2266,471,670,514,317,467,973,1652,211,437,144,453,1379,1825,1318,1402,1979
1.8129860846850323,0.5320690778198703,-0.26994204317439974,-0.03639319191522044,0.7512423742579706,2.2301995822122382,1.6994075847691243,0.9285450565881448,-0.1178697283777986,0.3691543755103429,2.354405332523084,0.12357638308743593,1.0785056180895356,0.9402000549206043,-0.5852259038097922,-0.6442432998834845,-0.4256619663333324,-0.5267448194609747,0.4698828319614009,2.162388458299299,2.306895933969297,0.09718452280470133,0.14986255217829011,0.2925877034989214,-0.20037731236087014,-0.09059771360529514,1.247488927312642,0.8345684311908745,-1.169173172578633,-0.20037731236087014,0.3182087393302986,-0.36860244967466754,2.0840690101310213,-0.31204139030411787,1.40148779769058,-0.18655323709370267,-0.6442432998834845,0.7512423742579706,2.0048528443378144,-1.0575050455050043,3.464640376876938,-1.153099610160616,-0.1178697283777986,0.7392533700796472,1.3359159947113879,0.3564547613061034,0.14986255217829011,2.8567608273079417,-0.5413153919519684,-0.8246235312168924,-0.8246235312168924,-0.31204139030411787,0.11039372225624319,0.13673262131565084,0.6059317074422123,-0.8246235312168924,-0.4832296221450455,-0.20037731236087014,0.8227280921116075,0.5072645015459241,-0.03639319191522044,-0.9167574127737401,2.979105090473296,-0.7942051683058742,-0.8246235312168924,0.07068604002806808,-0.5852259038097922,-0.8398871595532866,-0.599929555682314,0.2280960394572554,0.41971025795795724,1.7305705557513118,2.8655702953924993,0.8345684311908745,-0.1178697283777986,1.3906030399301132,1.4986744858114172,0.21512157560145628,-0.10421946745368259,0.6910807910791582,-0.39706930245536326,1.2586056494763058,-0.24202672664337113,-0.009458648363643903,0.2797397641478118,-1.9023594433529125,0.4698828319614009,0.3437306859841643,-0.009458648363643903,-0.25596938782450307,-0.26994204317439974,2.2205527471728286,-0.67395649066749,0.05739652070350504,0.2280960394572554,0.6181627463554006,1.2140287489707773,-0.3828202251674292,-0.5122071076002075,0.8581864580997747,-0.18655323709370267,2.7322585802245523,-0.35441582638841634,0.12357638308743593,-0.6442432998834845,-0.7038078525879563,0.8345684311908745,-0.8093962635979561,-1.4488767491086494,-0.22811391955386917,-0.46878952976590854,0.6668633638533525,1.954877326542401,-0.2979779017776956,1.1466073449079757,0.11039372225624319,2.4297531039738196,2.614643040475254,2.532046451483146,0.14986255217829011,0.5691030270776883,1.157891088460552,0.04407999074490389,-0.5267448194609747,1.1012827099190845,1.6261375988927858,0.11039372225624319,0.678983077713463,1.594494252228917,-1.201443286855556,0.030736330125996712,-0.8093962635979561,-0.8246235312168924,-0.7038078525879563,1.444853358337915,1.4986744858114172,0.5320690778198703,0.1760439488988051,1.573316957055108,-0.36860244967466754,-1.2828467850991063,0.8699643062088395,0.017365417996363004,-0.26994204317439974,0.8345684311908745,-0.39706930245536326,0.6425575843066014,0.09718452280470133,-0.35441582638841634,0.6910807910791582,0.5936781351799993,0.07068604002806808,-0.599929555682314,-0.326135443565647,2.3921809662769813,2.239833036702955,1.7821961261129045,2.133122344403906,0.7632098916182667,-0.24202672664337113,0.8934580688928646,-0.5852259038097922,0.9051741409295114,0.6059317074422123,0.8345684311908745,1.269704145648055,0.9168697776340057,0.25396851053519315,-0.25596938782450307,1.594494252228917,0.9634495159911116,1.9045369603750726,0.9402000549206043,-0.07700433730373651,-0.34026020681916364,-0.03639319191522044,-0.09059771360529514,-0.4256619663333324
3,040
Sterol metabolic process
15
39
2.792154
0.005236
Q14849,Q16850,Q14534,Q9BQE5,Q15800,Q9H2C2,P16435,P00387,P14324,P04062,Q14739,Q15392,Q8WTV0,P05067,O15118
Processes and pathways
GO Biological process
msigdb_gobp
32,257,194,11,109,398,175,207,401,180,116,150,221,126,255
255,875,589,207,180,126,1009,401,175,1201,582,475,2988,2837,1634,2302,2203,983,410,2861,2324,624,2649,194,116,32,2306,712,2620,150,2814,109,257,937,221,11,398,1653,2162
1.466432896979965,0.3564547613061034,0.7031565908693913,1.594494252228917,1.7305705557513118,2.0048528443378144,0.2021214798149985,1.0441949184190364,1.7512674340218852,0.04407999074490389,0.7152105634749184,0.8934580688928646,-1.6367289091365962,-1.073337763713145,-0.25596938782450307,-0.6146668929180736,-0.5559189875116972,0.2280960394572554,1.0097084148679092,-1.1370667422921092,-0.6294380842913514,0.6547215620472547,-0.8858981156239302,1.6681021781961047,2.0939075243292486,2.883156326889429,-0.6146668929180736,0.5567813080560997,-0.8551873385144706,1.8639980435174222,-1.0417117055833216,2.162388458299299,1.466432896979965,0.2925877034989214,1.5627036240741825,3.3914306381259736,1.055651255437339,-0.25596938782450307,-0.5267448194609747
3,040
Regulated exocytosis
14
33
2.78935
0.005281
Q15907,Q4J6C6,P11279,P49755,P09601,P0DP25,Q9BRK5,P16615,Q13277,Q7L0J3,P61026,O95721,O43760,Q9P253
Processes and pathways
GO Biological process
msigdb_gobp
129,451,261,517,9,72,495,336,368,369,308,590,88,480
2443,1243,815,1984,88,1745,590,1221,9,72,261,336,1961,1446,2616,517,1635,1124,1374,2345,308,1908,757,368,1563,631,129,451,2675,369,495,480,1261
-0.7187857872122325,0.017365417996363004,0.43228908847773645,-0.4400058576962713,2.306895933969297,-0.31204139030411787,0.7031565908693913,0.030736330125996712,3.464640376876938,2.3921809662769813,1.455651681499925,1.2252005430134607,-0.4256619663333324,-0.13154862682021135,-0.8551873385144706,0.8227280921116075,-0.25596938782450307,0.11039372225624319,-0.07700433730373651,-0.6442432998834845,1.291846719852825,-0.39706930245536326,0.5072645015459241,1.135304704632808,-0.21423082748473318,0.6425575843066014,1.9749109921081565,0.9402000549206043,-0.9013091013207586,1.135304704632808,0.8699643062088395,0.8934580688928646,0.017365417996363004
3,040
Alcohol binding
9
18
2.776996
0.005486
O95772,Q14849,P35610,P45880,Q14108,O94905,P21796,P61916,O15118
Functions
GO Molecular function
msigdb_gomf
193,32,582,45,272,589,85,410,255
804,255,622,875,589,193,2083,1853,85,1664,1809,582,45,410,272,32,1216,1596
0.4448440621115383,1.466432896979965,0.6547215620472547,0.3564547613061034,0.7031565908693913,1.6681021781961047,-0.497702095159616,-0.36860244967466754,2.3164237833166905,-0.26994204317439974,-0.34026020681916364,0.7152105634749184,2.7142915025133245,1.0097084148679092,1.4232051513701809,2.883156326889429,0.04407999074490389,-0.22811391955386917
3,040
Retrograde vesicle mediated transport golgi to endoplasmic reticulum
15
26
2.774529
0.005528
O15258,P24390,O43731,Q9Y282,P49755,Q96RQ1,Q12907,Q9P2W9,Q6NUQ1,P48739,O75396,Q12981,Q9H4A6,O14579,Q9H9E3
Processes and pathways
GO Biological process
msigdb_gobp
382,38,197,39,517,267,617,46,652,744,527,209,602,187,612
187,382,197,527,1321,38,1123,2392,1541,744,517,2278,2370,1562,617,209,652,1213,775,1129,267,602,612,46,2940,39
1.6994075847691243,1.0785056180895356,1.636652908380764,0.7989843584173286,-0.04990220374204181,2.8567608273079417,0.11039372225624319,-0.67395649066749,-0.20037731236087014,0.5196783799645482,0.8227280921116075,-0.599929555682314,-0.6590827110965932,-0.21423082748473318,0.6668633638533525,1.594494252228917,0.6181627463554006,0.04407999074490389,0.4823668232401796,0.11039372225624319,1.444853358337915,0.6910807910791582,0.678983077713463,2.7142915025133245,-1.3321976873356531,2.830266254288787
3,040
Biliary tract abnormality
8
24
2.767379
0.005651
P07602,P09601,Q9NZJ7,Q14108,P04062,Q10713,Q14739,Q5XKP0
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
266,9,138,272,180,279,116,122
700,488,708,2144,180,266,9,1222,2150,1833,755,1427,279,1092,272,116,122,1940,938,2267,138,370,1654,2227
0.5691030270776883,0.8699643062088395,0.5567813080560997,-0.5267448194609747,1.7305705557513118,1.444853358337915,3.464640376876938,0.030736330125996712,-0.5267448194609747,-0.35441582638841634,0.5072645015459241,-0.1178697283777986,1.40148779769058,0.13673262131565084,1.4232051513701809,2.0939075243292486,2.0445744152136456,-0.4113498322372873,0.2925877034989214,-0.5852259038097922,1.9347852868226298,1.135304704632808,-0.25596938782450307,-0.5559189875116972
3,040
Bulbar signs
6
12
2.756578
0.005841
P03886,P07602,Q99720,Q9NZJ7,P04062,P00846
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
195,266,136,138,180,22
700,22,195,180,1370,266,289,1203,2491,136,138,2873
0.5691030270776883,3.0993713176235196,1.6576351441981245,1.7305705557513118,-0.07700433730373651,1.444853358337915,1.3578437107911476,0.04407999074490389,-0.7488470548949705,1.9347852868226298,1.9347852868226298,-1.153099610160616
3,040
Azurophil granule membrane
14
24
2.747175
0.006011
O15260,Q07065,P11279,Q9H0U3,P07602,Q9NZJ7,P42785,O60784,P10253,P27105,O95721,P15291,Q92542,Q8NF37
Localization
GO Cellular component
msigdb_gocc
448,196,261,427,266,138,743,268,400,181,590,564,349,411
740,448,268,2445,2706,590,266,400,261,564,181,1460,743,995,1124,196,1191,411,349,1097,1944,427,138,1921
0.5196783799645482,0.9402000549206043,1.4340378681739008,-0.7187857872122325,-0.9322432477268474,0.7031565908693913,1.444853358337915,1.0441949184190364,1.455651681499925,0.7392533700796472,1.7305705557513118,-0.1452562941458644,0.5196783799645482,0.21512157560145628,0.11039372225624319,1.6471520721581714,0.05739652070350504,1.0097084148679092,1.1916296245752864,0.13673262131565084,-0.4113498322372873,0.9866187689477497,1.9347852868226298,-0.39706930245536326
3,040
Cherry red spot of the macula
6
9
2.739077
0.006161
P07602,P17900,Q9NZJ7,P10619,P06865,Q13510
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
266,169,138,84,246,54
246,266,1520,84,2482,294,169,54,138
1.4879442405996233,1.444853358337915,-0.18655323709370267,2.3259386091701724,-0.7488470548949705,1.3359159947113879,1.7821961261129045,2.532046451483146,1.9347852868226298
3,040
Phospholipid metabolic process
34
79
2.729221
0.006348
Q86YN1,Q99623,Q5H8A4,Q86SQ9,Q96N66,Q8WUK0,Q9UG56,Q9UJZ1,P14324,Q10713,Q8NF37,Q9NXE4,Q08AM6,Q9BTU6,Q8NCC3,O95674,Q7L5N7,O15269,P40939,Q9NX62,Q9NUQ2,Q9NPH0,O15270,Q9NTJ5,Q8WTV0,P37268,Q92643,Q8NEB9,Q8NHP8,O60762,Q9NP80,Q96S52,Q05655,Q9HBU6
Processes and pathways
GO Biological process
msigdb_gobp
3,646,130,134,269,396,144,671,401,279,411,548,161,546,423,551,693,431,688,467,205,80,719,471,221,475,608,105,239,622,111,625,243,513
2982,1694,804,431,719,852,622,2580,941,551,2902,2341,1520,401,2852,2411,1068,2368,1426,475,688,1186,1962,952,2859,2845,2324,2907,243,161,279,1527,2649,2620,130,870,937,693,134,750,3,1234,978,423,105,411,239,1290,221,396,986,769,608,1042,269,849,625,1917,646,859,546,1115,1216,971,513,1047,111,80,1713,471,205,467,548,1921,1652,144,1490,671,2873
-1.5849348762619273,-0.28394483378593255,0.4448440621115383,0.9634495159911116,0.5444366893129593,0.3818296309293903,0.6547215620472547,-0.8246235312168924,0.2797397641478118,0.7632098916182667,-1.2338789162429935,-0.6442432998834845,-0.18655323709370267,1.0441949184190364,-1.105122195917912,-0.6888648126817407,0.14986255217829011,-0.6590827110965932,-0.1178697283777986,0.8934580688928646,0.581401938827193,0.05739652070350504,-0.4256619663333324,0.2668667355288736,-1.1370667422921092,-1.0892100749872293,-0.6294380842913514,-1.2338789162429935,1.4986744858114172,1.8129860846850323,1.40148779769058,-0.18655323709370267,-0.8858981156239302,-0.8551873385144706,1.9749109921081565,0.3691543755103429,0.2925877034989214,0.581401938827193,1.9347852868226298,0.5196783799645482,3.577057121137054,0.030736330125996712,0.2410449813533824,0.9866187689477497,2.1915315517867935,1.0097084148679092,1.509387857490035,-0.009458648363643903,1.5627036240741825,1.055651255437339,0.2280960394572554,0.49482734776906995,0.678983077713463,0.1760439488988051,1.4340378681739008,0.39448062923729826,0.6547215620472547,-0.39706930245536326,0.6303713421013281,0.3818296309293903,0.7751560059742102,0.12357638308743593,0.04407999074490389,0.25396851053519315,0.8345684311908745,0.1760439488988051,2.133122344403906,2.344929345274909,-0.28394483378593255,0.9051741409295114,1.6050583254928277,0.9168697776340057,0.7751560059742102,-0.39706930245536326,-0.25596938782450307,1.9045369603750726,-0.15899286265091292,0.6059317074422123,-1.153099610160616
3,040
Phospholipid metabolism
14
18
2.722279
0.006483
Q6P1A2,Q86UL3,Q96N66,O14735,Q7L5N7,O95674,Q9NUQ2,Q9NPH0,Q9UG56,Q8WUK0,Q99943,Q9HBU6,Q8NF37,Q92604
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
937,750,269,804,693,551,205,80,144,396,859,513,411,769
804,551,1426,952,937,693,750,411,396,769,269,859,513,1047,80,1713,205,144
0.4448440621115383,0.7632098916182667,-0.1178697283777986,0.2668667355288736,0.2925877034989214,0.581401938827193,0.5196783799645482,1.0097084148679092,1.055651255437339,0.49482734776906995,1.4340378681739008,0.3818296309293903,0.8345684311908745,0.1760439488988051,2.344929345274909,-0.28394483378593255,1.6050583254928277,1.9045369603750726
3,040
Nephrotic syndrome
11
25
2.720604
0.006516
P06280,O95470,P56192,Q07021,Q14108,Q8N1F7,Q05655,O95721,Q9BW27,Q8NCH0,Q9BT22
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
292,168,593,404,272,444,243,590,569,55,154
168,590,1031,292,1407,1124,2020,593,786,1209,243,404,616,272,855,444,55,1762,987,1465,154,569,1739,1876,2705
1.7821961261129045,0.7031565908693913,0.1760439488988051,1.3468887104804244,-0.10421946745368259,0.11039372225624319,-0.4543816604229582,0.7031565908693913,0.4698828319614009,0.04407999074490389,1.4986744858114172,1.0441949184190364,0.6668633638533525,1.4232051513701809,0.3818296309293903,0.9518348493105416,2.532046451483146,-0.31204139030411787,0.2280960394572554,-0.1452562941458644,1.8538258857549876,0.7392533700796472,-0.2979779017776956,-0.36860244967466754,-0.9167574127737401
3,040
Passive transmembrane transporter activity
19
32
2.71963
0.006536
Q9BVC6,P00846,Q8NE86,Q9C0H2,P24539,P45880,Q9P246,Q9UM00,Q99797,P06576,O75964,P51790,P21796,P56385,P56134,O96008,Q9Y277,Q96S66,Q8TDW0
Functions
GO Molecular function
msigdb_gomf
647,22,801,41,42,45,446,706,576,709,77,723,85,344,606,489,112,626,378
2543,974,77,489,22,709,2408,2083,911,85,42,2631,797,1989,45,2824,723,844,606,344,976,1908,801,378,626,576,647,41,446,706,112,1829
-0.7942051683058742,0.2410449813533824,2.354405332523084,0.8699643062088395,3.0993713176235196,0.5567813080560997,-0.6888648126817407,-0.497702095159616,0.30541065998888134,2.3164237833166905,2.785886251994729,-0.8705242595411103,0.45737527732568883,-0.4400058576962713,2.7142915025133245,-1.0575050455050043,0.5444366893129593,0.39448062923729826,0.678983077713463,1.2028384651163935,0.2410449813533824,-0.39706930245536326,0.45737527732568883,1.1012827099190845,0.6547215620472547,0.7272427947625875,0.6303713421013281,2.803671793152203,0.9518348493105416,0.5691030270776883,2.133122344403906,-0.34026020681916364
3,040
Protein transmembrane import into intracellular organelle
11
14
2.706933
0.006791
Q9HAV7,Q3ZCQ8,Q99595,O96008,O60830,O43615,P50542,Q15388,Q9Y5Y5,O14925,O75381
Processes and pathways
GO Biological process
msigdb_gobp
684,584,8,489,13,561,755,692,516,56,318
56,561,13,318,1500,754,489,2582,755,692,584,8,684,516
2.5228086401821996,0.7512423742579706,3.3339674069724357,1.2586056494763058,-0.172758465571682,0.5072645015459241,0.8699643062088395,-0.8246235312168924,0.5072645015459241,0.581401938827193,0.7152105634749184,3.4808081262608535,0.5936781351799993,0.8345684311908745
3,040
ER-Golgi transport
21
53
2.705625
0.006818
P49755,Q96RQ1,Q9Y6B6,O75396,Q5JRA6,Q9HCU5,Q9NR31,O95197,P24390,Q9Y282,P51572,Q9P2W9,O14579,P61019,P56962,O43731,Q15363,Q12981,O15155,O95249,O95070
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
517,267,657,527,538,540,285,29,38,39,552,46,187,573,450,197,595,209,334,343,117
187,863,334,899,2544,781,197,1538,527,1658,117,29,343,1807,1321,38,1123,1541,1227,517,552,2601,2278,2048,1374,450,573,2370,1151,1562,209,2751,595,2114,538,652,1844,999,1128,775,2491,267,2767,540,285,46,2940,1179,39,2251,1551,1979,657
1.6994075847691243,0.3691543755103429,1.2252005430134607,0.3182087393302986,-0.7942051683058742,0.4698828319614009,1.636652908380764,-0.20037731236087014,0.7989843584173286,-0.26994204317439974,2.0840690101310213,2.9356533136426415,1.2028384651163935,-0.34026020681916364,-0.04990220374204181,2.8567608273079417,0.11039372225624319,-0.20037731236087014,0.030736330125996712,0.8227280921116075,0.7632098916182667,-0.8398871595532866,-0.599929555682314,-0.46878952976590854,-0.07700433730373651,0.9402000549206043,0.7272427947625875,-0.6590827110965932,0.0839486679282727,-0.21423082748473318,1.594494252228917,-0.9789278954279232,0.7031565908693913,-0.5122071076002075,0.7870808006365844,0.6181627463554006,-0.35441582638841634,0.21512157560145628,0.11039372225624319,0.4823668232401796,-0.7488470548949705,1.444853358337915,-0.9945658344832891,0.7870808006365844,1.37970081375604,2.7142915025133245,-1.3321976873356531,0.07068604002806808,2.830266254288787,-0.5705557698197767,-0.20037731236087014,-0.4256619663333324,0.6181627463554006
3,040
Cns demyelination
7
14
2.702866
0.006874
Q5H8A4,P40855,Q9NR50,P07602,Q9NZJ7,Q15067,P51648
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
130,229,359,266,138,462,57
266,229,1780,490,57,1329,1784,462,130,1973,2125,736,359,138
1.444853358337915,1.5307642110055628,-0.326135443565647,0.8699643062088395,2.513558618811099,-0.04990220374204181,-0.326135443565647,0.9168697776340057,1.9749109921081565,-0.4256619663333324,-0.5122071076002075,0.5320690778198703,1.180402160098838,1.9347852868226298
3,040
Proton transmembrane transport
20
44
2.702769
0.006876
Q99623,P05141,Q9UJZ1,Q9UDW1,Q7KZN9,P00846,Q00325,P24539,P12235,Q96ES6,O00400,P13073,Q9H936,P06576,O75964,O14548,P56385,P56134,P05023,Q13423
Processes and pathways
GO Biological process
msigdb_gobp
646,387,671,20,280,22,536,42,172,178,51,186,717,709,77,588,344,606,496,249
51,964,588,1367,948,974,77,928,22,496,387,709,1283,2196,172,186,912,993,2773,42,2631,2916,1387,797,773,1989,2824,723,606,344,1056,536,249,280,836,178,2981,646,1595,717,20,1490,1716,671
2.623760656175141,0.25396851053519315,0.7031565908693913,-0.07700433730373651,0.2668667355288736,0.2410449813533824,2.354405332523084,0.2925877034989214,3.0993713176235196,0.8581864580997747,1.0670881313408322,0.5567813080560997,-0.009458648363643903,-0.5559189875116972,1.76159249707139,1.709810998068712,0.30541065998888134,0.21512157560145628,-1.010242310415109,2.785886251994729,-0.8705242595411103,-1.2664819236308702,-0.09059771360529514,0.45737527732568883,0.4823668232401796,-0.4400058576962713,-1.0575050455050043,0.5444366893129593,0.678983077713463,1.2028384651163935,0.16296629013982664,0.7870808006365844,1.4771970637826917,1.40148779769058,0.40710747145539755,1.7409268040090475,-1.5677651074261831,0.6303713421013281,-0.22811391955386917,0.5567813080560997,3.158748918172827,-0.15899286265091292,-0.28394483378593255,0.6059317074422123
3,040
Endoplasmic reticulum protein containing complex
28
60
2.699407
0.006946
Q9BUN8,Q9UGP8,Q6NUQ1,Q9UBV2,Q9NPA0,P62942,Q9H0U3,P04439,P07237,Q15006,O15269,P67812,Q03518,P13674,Q15005,O43681,Q53GQ0,P51571,Q9UBU6,P49458,Q15041,P46977,Q9Y5M8,Q92643,P04844,Q96S52,Q8N4V1,Q8TCT9
Localization
GO Cellular component
msigdb_gocc
128,520,652,413,541,157,427,562,307,434,431,182,312,440,574,700,324,329,211,722,601,348,227,608,228,625,247,124
431,719,2544,852,1954,700,562,968,228,307,440,1746,1580,2614,2429,2746,1460,348,722,329,1583,1461,1055,976,2737,157,182,312,1863,881,2112,574,434,601,2155,324,788,652,1257,247,837,2657,1095,124,608,1419,1042,884,625,128,427,971,541,211,413,520,2424,2640,227,1217
0.9634495159911116,0.5444366893129593,-0.7942051683058742,0.3818296309293903,-0.4256619663333324,0.5691030270776883,0.7512423742579706,0.25396851053519315,1.5307642110055628,1.291846719852825,0.9518348493105416,-0.31204139030411787,-0.22811391955386917,-0.8551873385144706,-0.7038078525879563,-0.9789278954279232,-0.1452562941458644,1.1916296245752864,0.5444366893129593,1.2363539137486759,-0.22811391955386917,-0.1452562941458644,0.16296629013982664,0.2410449813533824,-0.9633282872250349,1.8334363171266495,1.7305705557513118,1.2807844808764448,-0.36860244967466754,0.3564547613061034,-0.5122071076002075,0.7272427947625875,0.9634495159911116,0.6910807910791582,-0.5267448194609747,1.247488927312642,0.4698828319614009,0.6181627463554006,0.017365417996363004,1.4879442405996233,0.40710747145539755,-0.8858981156239302,0.13673262131565084,2.0445744152136456,0.678983077713463,-0.10421946745368259,0.1760439488988051,0.3564547613061034,0.6547215620472547,1.994886652159444,0.9866187689477497,0.25396851053519315,0.7870808006365844,1.594494252228917,1.0097084148679092,0.8227280921116075,-0.6888648126817407,-0.8705242595411103,1.541427307462825,0.04407999074490389
3,040
Molecular carrier activity
19
35
2.697852
0.006979
Q5J8M3,Q9C0E2,Q8N8Q8,P55060,O75880,Q9NPA0,O43819,Q53FT3,Q8TEX9,Q92973,P62072,O00410,Q15006,P52292,Q15070,Q9HAV4,P40855,Q8N4V1,Q96P70
Functions
GO Molecular function
msigdb_gomf
788,275,148,785,407,541,795,33,677,424,43,803,434,441,60,737,229,247,636
803,1015,1773,1065,1954,795,1196,407,2082,2274,1750,229,441,1636,785,43,1585,1297,434,60,33,788,247,837,148,677,424,636,2981,275,737,541,1242,1573,2227
0.4448440621115383,0.18909564139474644,-0.326135443565647,0.14986255217829011,-0.4256619663333324,0.45737527732568883,0.04407999074490389,1.0212235711320679,-0.497702095159616,-0.599929555682314,-0.31204139030411787,1.5307642110055628,0.9518348493105416,-0.25596938782450307,0.4698828319614009,2.785886251994729,-0.22811391955386917,-0.022912048485096835,0.9634495159911116,2.495021804682221,2.883156326889429,0.4698828319614009,1.4879442405996233,0.40710747145539755,1.87415518169426,0.5936781351799993,0.9866187689477497,0.6425575843066014,-1.5677651074261831,1.4123551479690624,0.5320690778198703,0.7870808006365844,0.030736330125996712,-0.21423082748473318,-0.5559189875116972
3,040
Cristae formation
14
21
2.696767
0.007002
Q13505,Q9NVH1,P56385,P56134,P24539,P06576,P17152,O75964,Q16891,Q9BUR5,P00846,Q9NX63,Q9Y512,Q5XKP0
Processes and pathways
Reactome Pathways
msigdb_reactome
96,718,344,606,42,709,428,77,361,49,22,515,447,122
707,974,77,22,709,428,42,2631,797,2727,2824,606,344,96,361,122,916,49,718,515,447
0.5567813080560997,0.2410449813533824,2.354405332523084,3.0993713176235196,0.5567813080560997,0.97504413075297,2.785886251994729,-0.8705242595411103,0.45737527732568883,-0.9477668055435992,-1.0575050455050043,0.678983077713463,1.2028384651163935,2.249453151058262,1.1691560040620224,2.0445744152136456,0.30541065998888134,2.6510426426330733,0.5567813080560997,0.8345684311908745,0.9518348493105416
3,040
Abnormal activity of mitochondrial respiratory chain
12
55
2.691211
0.007119
P03886,Q9Y584,Q96CU9,Q86Y39,Q9Y2R0,O96000,O60783,O43676,Q7KZN9,P13073,Q9UBX3,Q70HW3
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
195,69,102,135,10,265,48,82,280,186,62,61
964,82,2755,48,948,481,1104,806,1577,265,195,2014,186,2805,912,565,3015,2876,2168,1780,1963,2633,1410,1966,2257,1036,2557,1212,584,1815,1394,61,280,135,789,102,1467,1789,1595,2093,988,1893,1024,484,861,1241,290,2660,62,10,2097,1366,69,1628,1165
0.25396851053519315,2.335440450294008,-0.9945658344832891,2.6691719156596547,0.2668667355288736,0.8817214834855824,0.12357638308743593,0.4448440621115383,-0.22811391955386917,1.444853358337915,1.6576351441981245,-0.4543816604229582,1.709810998068712,-1.0417117055833216,0.30541065998888134,0.7392533700796472,-2.14215547799472,-1.169173172578633,-0.5413153919519684,-0.326135443565647,-0.4256619663333324,-0.8705242595411103,-0.10421946745368259,-0.4256619663333324,-0.5852259038097922,0.1760439488988051,-0.7942051683058742,0.04407999074490389,0.7152105634749184,-0.34026020681916364,-0.09059771360529514,2.495021804682221,1.40148779769058,1.9347852868226298,0.4698828319614009,2.2205527471728286,-0.1452562941458644,-0.326135443565647,-0.22811391955386917,-0.497702095159616,0.2280960394572554,-0.3828202251674292,0.18909564139474644,0.8817214834855824,0.3818296309293903,0.030736330125996712,1.3578437107911476,-0.8858981156239302,2.495021804682221,3.432195062095224,-0.497702095159616,-0.06343920992511146,2.4391146215009063,-0.24202672664337113,0.0839486679282727
3,040
Calcium-binding protein
7
19
2.686201
0.007227
O43852,P43307,Q14257,P80303,P0DP25,Q02818,P41208
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
352,2,165,36,72,282,31
352,72,2429,1147,31,2,914,1353,36,282,165,1139,1544,2962,356,2921,680,495,1120
1.180402160098838,2.3921809662769813,-0.7038078525879563,0.0839486679282727,2.9181976011109048,3.577057121137054,0.30541065998888134,-0.06343920992511146,2.8655702953924993,1.3906030399301132,1.8027380962357773,0.09718452280470133,-0.20037731236087014,-1.4488767491086494,1.180402160098838,-1.2664819236308702,0.5936781351799993,0.8699643062088395,0.12357638308743593
3,040
Ion channel complex
6
17
2.68292
0.007298
Q8IYU8,Q9H4I9,P0DP25,Q9C0H2,Q86WC4,P62942
Localization
GO Cellular component
msigdb_gocc
356,7,72,41,83,157
2543,72,844,157,1254,2073,83,356,978,801,378,626,1873,680,41,7,1829
-0.7942051683058742,2.3921809662769813,0.39448062923729826,1.8334363171266495,0.017365417996363004,-0.4832296221450455,2.335440450294008,1.180402160098838,0.2410449813533824,0.45737527732568883,1.1012827099190845,0.6547215620472547,-0.36860244967466754,0.5936781351799993,2.803671793152203,3.513034705457238,-0.34026020681916364
3,040
Protein localization to endoplasmic reticulum
17
36
2.664921
0.007701
O15258,Q9Y5M8,O43681,Q9NQC3,P24390,Q9UGP8,O43731,Q9UHB9,Q96HY6,P46379,P51572,P61026,Q99442,Q15042,Q5JRA6,Q15629,Q15005
Processes and pathways
GO Biological process
msigdb_gobp
382,227,700,68,38,520,197,90,357,673,552,308,509,631,538,125,574
863,382,852,700,197,1051,2194,2013,2958,2149,38,2199,673,722,552,1461,1607,1055,2279,308,976,574,631,125,538,1129,357,509,1741,1621,68,1921,520,90,1179,227
0.3691543755103429,1.0785056180895356,0.3818296309293903,0.5691030270776883,1.636652908380764,0.16296629013982664,-0.5559189875116972,-0.4543816604229582,-1.4153183707260697,-0.5267448194609747,2.8567608273079417,-0.5559189875116972,0.5936781351799993,0.5444366893129593,0.7632098916182667,-0.1452562941458644,-0.24202672664337113,0.16296629013982664,-0.599929555682314,1.291846719852825,0.2410449813533824,0.7272427947625875,0.6425575843066014,2.024742179505935,0.7870808006365844,0.11039372225624319,1.180402160098838,0.8345684311908745,-0.2979779017776956,-0.24202672664337113,2.4391146215009063,-0.39706930245536326,0.8227280921116075,2.297355022185028,0.07068604002806808,1.541427307462825
3,040
Inorganic anion transport
15
23
2.662621
0.007753
O43681,Q9C0H2,P45880,Q9UHG3,Q8TDW0,Q9Y277,Q96S66,Q86WC4,P51790,O43826,P21796,Q00325,P54105,Q9UBX3,P55011
Processes and pathways
GO Biological process
msigdb_gobp
700,41,45,142,378,112,626,83,723,405,85,536,442,62,630
2543,700,405,818,911,85,45,723,844,442,630,536,745,3012,83,378,626,41,1378,62,142,112,1829
-0.7942051683058742,0.5691030270776883,1.0327190479133637,0.43228908847773645,0.30541065998888134,2.3164237833166905,2.7142915025133245,0.5444366893129593,0.39448062923729826,0.9518348493105416,0.6425575843066014,0.7870808006365844,0.5196783799645482,-2.0673749691364636,2.335440450294008,1.1012827099190845,0.6547215620472547,2.803671793152203,-0.07700433730373651,2.495021804682221,1.9146345006853838,2.133122344403906,-0.34026020681916364
3,040
Intrinsic component of mitochondrial outer membrane
9
13
2.661119
0.007788
O95140,P50416,Q9UH62,Q9GZY8,O96008,Q8IWA4,Q9BWH2,Q15388,P57105
Localization
GO Cellular component
msigdb_gocc
796,583,453,426,489,694,215,692,24
1500,796,489,583,24,692,694,1155,1172,838,215,426,453
-0.172758465571682,0.45737527732568883,0.8699643062088395,0.7152105634749184,3.090848153872596,0.581401938827193,0.581401938827193,0.0839486679282727,0.07068604002806808,0.40710747145539755,1.583913814546594,0.9866187689477497,0.9402000549206043
3,040
Gpcr ligand binding
6
10
2.650869
0.008028
P07602,Q9NZJ7,P42892,P04083,P05067,P63218
Processes and pathways
Reactome Pathways
msigdb_reactome
266,138,208,373,126,415
373,126,266,208,415,1079,479,138,1119,830
1.112642456885775,2.0048528443378144,1.444853358337915,1.594494252228917,0.9981735054914589,0.14986255217829011,0.8934580688928646,1.9347852868226298,0.12357638308743593,0.41971025795795724
3,040
Endoplasmic reticulum
81
205
2.65064
0.008034
O43169,P43307,Q9UGP8,Q99735,Q92575,P18031,P50402,P84157,Q9HCU5,O95197,Q9NZ01,Q14849,P51572,Q9P2W9,O95674,Q9Y680,P51648,Q5T9L3,Q9NQC3,P35610,Q96GC9,O94905,P21964,Q15041,P67809,Q96PC5,Q99956,Q15800,Q96KA5,Q9H6H4,O96005,Q8N0U8,Q8TCT9,Q9BUN8,Q96G23,Q86UE4,Q70UQ0,Q9BV10,Q96A57,Q9BT22,Q8IV08,Q96A33,Q14257,O95470,O60831,O43731,P00387,Q12981,Q9P035,P04844,Q8NHH9,Q16799,Q05655,Q16850,Q9NR31,O00264,P07237,Q92791,Q03518,Q9Y5U9,P51571,Q00765,Q96AG4,Q6NUQ4,Q86XL3,Q9H3N1,O43852,Q96HY6,Q96KC8,Q6UW68,Q13409,P27824,Q8NF37,O15269,P13674,O15260,P37268,Q96CN7,Q99442,Q9H3G5,Q9H0U4
Localization
Protein Atlas Subcellular
protein_atlas_subcellular_location_all
0,2,520,518,523,528,534,535,540,29,549,32,552,46,551,50,57,65,68,582,79,589,86,601,607,99,620,109,118,119,121,123,124,128,133,141,147,149,152,154,158,162,165,168,184,197,207,209,224,228,235,238,243,257,285,299,307,313,312,328,329,330,337,341,345,346,352,357,362,375,388,402,411,431,440,448,475,494,509,511,510
2038,299,851,1477,863,448,431,720,0,2544,852,1954,197,352,927,184,875,742,876,589,29,1721,168,551,121,207,968,228,1445,2545,1145,307,2949,2147,911,1407,2851,440,1746,1580,1723,528,1747,1926,2343,2806,86,2614,1247,2692,843,1088,2429,402,2644,2746,2044,2792,1123,582,1426,1604,475,1460,2917,2,1902,2869,1582,1903,2504,2547,952,1931,1227,534,2277,2973,329,552,57,1461,2509,2552,2748,1328,976,2737,2809,1668,1524,2281,1638,1355,1584,2435,2712,2695,1151,2453,1968,2235,1993,2572,1295,2794,2153,2022,1608,607,2454,1969,535,330,312,243,1937,1640,209,846,691,388,2846,165,1588,1997,2112,32,601,2155,712,1139,828,2814,109,238,257,2878,1094,65,1484,341,2026,375,147,693,141,1644,345,1127,158,1234,123,985,2308,411,235,667,1095,124,1336,760,523,313,162,152,337,494,884,133,79,357,118,362,99,626,509,518,859,620,1516,154,128,149,510,511,346,119,540,68,285,2719,549,224,1921,2768,46,1653,1143,520,706,1180,328,50,657
-0.46878952976590854,1.3249255008810943,0.3818296309293903,-0.15899286265091292,0.3691543755103429,0.9402000549206043,0.9634495159911116,0.5444366893129593,3.577057121137054,-0.7942051683058742,0.3818296309293903,-0.4256619663333324,1.636652908380764,1.180402160098838,0.2925877034989214,1.720198637706239,0.3564547613061034,0.5196783799645482,0.3564547613061034,0.7031565908693913,2.9356533136426415,-0.2979779017776956,1.7821961261129045,0.7632098916182667,2.0643499077857936,1.594494252228917,0.25396851053519315,1.5307642110055628,-0.13154862682021135,-0.7942051683058742,0.0839486679282727,1.291846719852825,-1.3819382187689992,-0.5267448194609747,0.30541065998888134,-0.10421946745368259,-1.105122195917912,0.9518348493105416,-0.31204139030411787,-0.22811391955386917,-0.2979779017776956,0.7989843584173286,-0.31204139030411787,-0.4113498322372873,-0.6442432998834845,-1.0417117055833216,2.3164237833166905,-0.8551873385144706,0.017365417996363004,-0.9167574127737401,0.39448062923729826,0.13673262131565084,-0.7038078525879563,1.0441949184190364,-0.8858981156239302,-0.9789278954279232,-0.46878952976590854,-1.025957530959372,0.11039372225624319,0.7152105634749184,-0.1178697283777986,-0.24202672664337113,0.8934580688928646,-0.1452562941458644,-1.2664819236308702,3.577057121137054,-0.39706930245536326,-1.153099610160616,-0.22811391955386917,-0.39706930245536326,-0.7639307486259913,-0.7942051683058742,0.2668667355288736,-0.4113498322372873,0.030736330125996712,0.7870808006365844,-0.599929555682314,-1.516536577941719,1.2363539137486759,0.7632098916182667,2.513558618811099,-0.1452562941458644,-0.7639307486259913,-0.7942051683058742,-0.9789278954279232,-0.04990220374204181,0.2410449813533824,-0.9633282872250349,-1.0417117055833216,-0.26994204317439974,-0.18655323709370267,-0.599929555682314,-0.25596938782450307,-0.06343920992511146,-0.22811391955386917,-0.7038078525879563,-0.9322432477268474,-0.9167574127737401,0.0839486679282727,-0.7187857872122325,-0.4256619663333324,-0.5705557698197767,-0.4400058576962713,-0.8093962635979561,-0.022912048485096835,-1.025957530959372,-0.5267448194609747,-0.4543816604229582,-0.24202672664337113,0.678983077713463,-0.7187857872122325,-0.4256619663333324,0.7870808006365844,1.2363539137486759,1.2807844808764448,1.4986744858114172,-0.4113498322372873,-0.25596938782450307,1.594494252228917,0.39448062923729826,0.581401938827193,1.0670881313408322,-1.0892100749872293,1.8027380962357773,-0.22811391955386917,-0.4400058576962713,-0.5122071076002075,2.883156326889429,0.6910807910791582,-0.5267448194609747,0.5567813080560997,0.09718452280470133,0.41971025795795724,-1.0417117055833216,2.162388458299299,1.509387857490035,1.466432896979965,-1.169173172578633,0.13673262131565084,2.4671241214659725,-0.15899286265091292,1.2140287489707773,-0.4543816604229582,1.112642456885775,1.87415518169426,0.581401938827193,1.9146345006853838,-0.25596938782450307,1.2028384651163935,0.11039372225624319,1.8334363171266495,0.030736330125996712,2.0445744152136456,0.2280960394572554,-0.6146668929180736,1.0097084148679092,1.5200844134010096,0.6059317074422123,0.13673262131565084,2.0445744152136456,-0.04990220374204181,0.5072645015459241,0.8108667616335737,1.2807844808764448,1.8129860846850323,1.8639980435174222,1.2252005430134607,0.8699643062088395,0.3564547613061034,1.9448386266327375,2.354405332523084,1.180402160098838,2.0742164858122125,1.1691560040620224,2.2301995822122382,0.6547215620472547,0.8345684311908745,0.8227280921116075,0.3818296309293903,0.6668633638533525,-0.172758465571682,1.8538258857549876,1.994886652159444,1.87415518169426,0.8345684311908745,0.8345684311908745,1.2028384651163935,2.0742164858122125,0.7870808006365844,2.4391146215009063,1.37970081375604,-0.9322432477268474,0.7751560059742102,1.5520737596319365,-0.39706930245536326,-0.9945658344832891,2.7142915025133245,-0.25596938782450307,0.09718452280470133,0.8227280921116075,0.5691030270776883,0.07068604002806808,1.247488927312642,2.6510426426330733,0.6181627463554006
3,040
Purine containing compound transmembrane transport
6
8
2.648181
0.008093
P05141,P12235,P12236,Q8TDW0,Q8TB61,Q99808
Processes and pathways
GO Biological process
msigdb_gobp
387,172,143,378,251,316
414,387,172,143,1148,251,378,316
0.9981735054914589,1.0670881313408322,1.76159249707139,1.9045369603750726,0.0839486679282727,1.4771970637826917,1.1012827099190845,1.269704145648055
3,040
Cation transport
56
144
2.644562
0.00818
Q15907,Q99623,P98194,Q9HC21,Q9H4I9,P20020,P05141,P55011,Q9UJZ1,Q9UDW1,P00846,Q7KZN9,Q00325,P62942,O43808,Q9BPX6,Q9H0U3,P24539,P12235,Q96ES6,Q9HD20,O00400,Q96PU5,P27105,Q96HE7,P13073,O75844,Q9UM00,Q70HW3,Q99808,Q9P246,Q9H936,O76024,Q9HD47,P0DP25,P54709,P06576,O75964,Q96GC9,P16615,Q9Y619,O14548,O00429,P21796,P56385,Q9HC07,P56134,Q8IYU8,P78417,O95202,O75027,P05023,O15173,Q8N4V1,Q13423,P05067
Processes and pathways
GO Biological process
msigdb_gobp
129,646,503,260,7,642,387,630,671,20,22,280,536,157,414,680,427,42,172,178,179,51,568,181,445,186,59,706,61,316,446,717,323,71,72,710,709,77,79,336,81,588,468,85,344,97,606,356,106,488,486,496,114,247,249,126
2443,51,468,964,588,815,114,1367,925,414,1345,2597,486,948,1265,1851,1497,59,974,77,323,488,2522,928,22,865,1221,496,126,387,1145,709,2408,2409,2083,842,1283,72,2196,1960,1009,172,186,1184,336,2524,2411,642,912,993,2773,3010,85,42,1323,2631,181,2471,2916,1311,1387,1459,1108,2759,797,773,1989,2392,2587,1700,2824,1312,723,1124,710,630,606,344,1269,1056,2205,976,915,157,106,503,536,1908,2416,1812,933,757,2372,2738,2974,249,2456,2811,1752,2073,882,129,1212,1375,61,280,1565,356,247,836,801,1072,178,79,445,568,2981,646,316,1873,680,1595,427,1893,2538,7,717,1116,97,260,179,71,446,20,1490,1716,671,2033,706,2359,1261,1120,1575,81
-0.7187857872122325,2.623760656175141,0.9051741409295114,0.25396851053519315,0.7031565908693913,0.43228908847773645,2.103732071785902,-0.07700433730373651,0.2925877034989214,0.9981735054914589,-0.06343920992511146,-0.8398871595532866,0.8699643062088395,0.2668667355288736,0.003967132673760511,-0.36860244967466754,-0.172758465571682,2.5042963521150807,0.2410449813533824,2.354405332523084,1.247488927312642,0.8699643062088395,-0.7790500584504968,0.2925877034989214,3.0993713176235196,0.3691543755103429,0.030736330125996712,0.8581864580997747,2.0048528443378144,1.0670881313408322,0.0839486679282727,0.5567813080560997,-0.6888648126817407,-0.6888648126817407,-0.497702095159616,0.39448062923729826,-0.009458648363643903,2.3921809662769813,-0.5559189875116972,-0.4256619663333324,0.2021214798149985,1.76159249707139,1.709810998068712,0.05739652070350504,1.2252005430134607,-0.7790500584504968,-0.6888648126817407,0.6303713421013281,0.30541065998888134,0.21512157560145628,-1.010242310415109,-1.9751564924160614,2.3164237833166905,2.785886251994729,-0.04990220374204181,-0.8705242595411103,1.7305705557513118,-0.7337987947728196,-1.2664819236308702,-0.03639319191522044,-0.09059771360529514,-0.1452562941458644,0.12357638308743593,-0.9945658344832891,0.45737527732568883,0.4823668232401796,-0.4400058576962713,-0.67395649066749,-0.8246235312168924,-0.28394483378593255,-1.0575050455050043,-0.03639319191522044,0.5444366893129593,0.11039372225624319,0.5567813080560997,0.6425575843066014,0.678983077713463,1.2028384651163935,0.003967132673760511,0.16296629013982664,-0.5559189875116972,0.2410449813533824,0.30541065998888134,1.8334363171266495,2.181830786620961,0.8345684311908745,0.7870808006365844,-0.39706930245536326,-0.6888648126817407,-0.34026020681916364,0.2925877034989214,0.5072645015459241,-0.6590827110965932,-0.9633282872250349,-1.516536577941719,1.4771970637826917,-0.7187857872122325,-1.0417117055833216,-0.31204139030411787,-0.4832296221450455,0.3564547613061034,1.9749109921081565,0.04407999074490389,-0.07700433730373651,2.495021804682221,1.40148779769058,-0.21423082748473318,1.180402160098838,1.4879442405996233,0.40710747145539755,0.45737527732568883,0.14986255217829011,1.7409268040090475,2.354405332523084,0.9518348493105416,0.7392533700796472,-1.5677651074261831,0.6303713421013281,1.269704145648055,-0.36860244967466754,0.5936781351799993,-0.22811391955386917,0.9866187689477497,-0.3828202251674292,-0.7790500584504968,3.513034705457238,0.5567813080560997,0.12357638308743593,2.239833036702955,1.466432896979965,1.7409268040090475,2.4297531039738196,0.9518348493105416,3.158748918172827,-0.15899286265091292,-0.28394483378593255,0.6059317074422123,-0.4543816604229582,0.5691030270776883,-0.6442432998834845,0.017365417996363004,0.12357638308743593,-0.21423082748473318,2.344929345274909
3,040
Steroid metabolic process
29
65
2.638108
0.008337
Q16850,O14734,Q9BQE5,Q9H2C2,Q99538,P14324,Q15392,P61916,Q14849,O95470,P16435,P04062,Q13510,Q8NBQ5,Q14534,Q53GQ0,P35610,P00387,O94905,Q8WTV0,P37268,P38435,Q15800,Q06520,P05023,Q14739,Q96SU4,P05067,O15118
Processes and pathways
GO Biological process
msigdb_gobp
257,641,11,398,532,401,150,410,32,168,175,180,54,566,194,324,582,207,589,221,475,225,109,624,496,116,245,126,255
641,255,875,589,168,207,180,496,126,2950,1009,401,2523,175,1068,1664,1201,2823,659,582,475,225,2988,2837,1634,2302,2859,1427,2203,983,410,2861,2324,933,624,54,2649,194,116,32,2306,712,2620,150,2653,2512,2814,109,257,324,1191,937,566,221,245,532,2989,11,398,1142,1596,1653,2162,1441,980
0.6303713421013281,1.466432896979965,0.3564547613061034,0.7031565908693913,1.7821961261129045,1.594494252228917,1.7305705557513118,0.8581864580997747,2.0048528443378144,-1.3819382187689992,0.2021214798149985,1.0441949184190364,-0.7790500584504968,1.7512674340218852,0.14986255217829011,-0.26994204317439974,0.04407999074490389,-1.0575050455050043,0.6059317074422123,0.7152105634749184,0.8934580688928646,1.541427307462825,-1.6367289091365962,-1.073337763713145,-0.25596938782450307,-0.6146668929180736,-1.1370667422921092,-0.1178697283777986,-0.5559189875116972,0.2280960394572554,1.0097084148679092,-1.1370667422921092,-0.6294380842913514,0.2925877034989214,0.6547215620472547,2.532046451483146,-0.8858981156239302,1.6681021781961047,2.0939075243292486,2.883156326889429,-0.6146668929180736,0.5567813080560997,-0.8551873385144706,1.8639980435174222,-0.8858981156239302,-0.7639307486259913,-1.0417117055833216,2.162388458299299,1.466432896979965,1.247488927312642,0.05739652070350504,0.2925877034989214,0.7392533700796472,1.5627036240741825,1.4986744858114172,0.7989843584173286,-1.6367289091365962,3.3914306381259736,1.055651255437339,0.09718452280470133,-0.22811391955386917,-0.25596938782450307,-0.5267448194609747,-0.1178697283777986,0.2410449813533824
3,040
Glycerolipid biosynthetic process
27
49
2.633069
0.008462
Q5H8A4,Q8WUK0,Q96N66,Q9UG56,Q10713,Q8NF37,Q08AM6,Q9BTU6,Q8NCC3,O14735,Q7L5N7,O95674,Q96PE3,Q9NX62,Q9NUQ2,Q9NPH0,Q99943,Q9NTJ5,O43292,Q8WTV0,Q92643,Q86UL3,Q8NEB9,O60762,Q96S52,Q9HBU6,Q92604
Processes and pathways
GO Biological process
msigdb_gobp
130,396,269,144,279,411,161,546,423,804,693,551,849,467,205,80,859,471,852,221,608,750,105,622,625,513,769
1694,804,852,622,941,551,2902,2341,2852,1018,1426,1186,952,2845,2907,161,279,1527,130,870,937,693,750,423,105,411,1290,221,396,986,769,608,1042,269,849,625,1917,859,546,1115,971,513,1047,80,471,205,467,1652,144
-0.28394483378593255,0.4448440621115383,0.3818296309293903,0.6547215620472547,0.2797397641478118,0.7632098916182667,-1.2338789162429935,-0.6442432998834845,-1.105122195917912,0.18909564139474644,-0.1178697283777986,0.05739652070350504,0.2668667355288736,-1.0892100749872293,-1.2338789162429935,1.8129860846850323,1.40148779769058,-0.18655323709370267,1.9749109921081565,0.3691543755103429,0.2925877034989214,0.581401938827193,0.5196783799645482,0.9866187689477497,2.1915315517867935,1.0097084148679092,-0.009458648363643903,1.5627036240741825,1.055651255437339,0.2280960394572554,0.49482734776906995,0.678983077713463,0.1760439488988051,1.4340378681739008,0.39448062923729826,0.6547215620472547,-0.39706930245536326,0.3818296309293903,0.7751560059742102,0.12357638308743593,0.25396851053519315,0.8345684311908745,0.1760439488988051,2.344929345274909,0.9051741409295114,1.6050583254928277,0.9168697776340057,-0.25596938782450307,1.9045369603750726
3,040
Synaptic vesicle membrane
7
17
2.63187
0.008492
Q15907,O76024,P0DP25,O43752,Q7L0J3,O00429,O43760
Localization
GO Cellular component
msigdb_gocc
129,323,72,108,369,468,88
468,753,108,88,926,323,1745,1034,1776,72,642,1961,1019,1428,129,369,506
0.9051741409295114,0.5072645015459241,2.162388458299299,2.306895933969297,0.2925877034989214,1.247488927312642,-0.31204139030411787,0.1760439488988051,-0.326135443565647,2.3921809662769813,0.6303713421013281,-0.4256619663333324,0.18909564139474644,-0.1178697283777986,1.9749109921081565,1.135304704632808,0.8345684311908745
3,040
Nonalcoholic fatty liver disease
9
44
2.629074
0.008562
Q9P0J0,O14949,Q86Y39,O96000,Q96GC9,O43676,P14406,Q9UDW1,P13073
Processes and pathways
WikiPathways
msigdb_wp
290,37,135,265,79,82,19,20,186
964,588,991,37,82,948,481,300,1104,487,1577,265,928,1032,1283,2196,186,19,1224,2805,912,565,819,3015,2168,772,1387,820,2633,1635,1410,997,983,2473,1994,1785,1212,135,79,938,861,290,20,1165
0.25396851053519315,0.7031565908693913,0.21512157560145628,2.8567608273079417,2.335440450294008,0.2668667355288736,0.8817214834855824,1.3249255008810943,0.12357638308743593,0.8699643062088395,-0.22811391955386917,1.444853358337915,0.2925877034989214,0.1760439488988051,-0.009458648363643903,-0.5559189875116972,1.709810998068712,3.158748918172827,0.030736330125996712,-1.0417117055833216,0.30541065998888134,0.7392533700796472,0.43228908847773645,-2.14215547799472,-0.5413153919519684,0.4823668232401796,-0.09059771360529514,0.43228908847773645,-0.8705242595411103,-0.25596938782450307,-0.10421946745368259,0.21512157560145628,0.2280960394572554,-0.7337987947728196,-0.4400058576962713,-0.326135443565647,0.04407999074490389,1.9347852868226298,2.354405332523084,0.2925877034989214,0.3818296309293903,1.3578437107911476,3.158748918172827,0.0839486679282727
3,040
Secondary alcohol metabolic process
15
43
2.626629
0.008624
Q14849,Q16850,Q14534,Q9BQE5,Q15800,Q9H2C2,P16435,P00387,P14324,P04062,Q14739,Q15392,Q8WTV0,P05067,O15118
Processes and pathways
GO Biological process
msigdb_gobp
32,257,194,11,109,398,175,207,401,180,116,150,221,126,255
255,1406,875,2580,589,207,180,126,1009,401,175,1201,582,475,2837,1634,2838,2302,2548,2203,983,410,2861,2324,624,2649,194,116,32,2306,712,2620,150,2814,109,257,937,221,2785,11,398,1653,2162
1.466432896979965,-0.10421946745368259,0.3564547613061034,-0.8246235312168924,0.7031565908693913,1.594494252228917,1.7305705557513118,2.0048528443378144,0.2021214798149985,1.0441949184190364,1.7512674340218852,0.04407999074490389,0.7152105634749184,0.8934580688928646,-1.073337763713145,-0.25596938782450307,-1.073337763713145,-0.6146668929180736,-0.7942051683058742,-0.5559189875116972,0.2280960394572554,1.0097084148679092,-1.1370667422921092,-0.6294380842913514,0.6547215620472547,-0.8858981156239302,1.6681021781961047,2.0939075243292486,2.883156326889429,-0.6146668929180736,0.5567813080560997,-0.8551873385144706,1.8639980435174222,-1.0417117055833216,2.162388458299299,1.466432896979965,0.2925877034989214,1.5627036240741825,-1.010242310415109,3.3914306381259736,1.055651255437339,-0.25596938782450307,-0.5267448194609747
3,040
Specific granule membrane
6
18
2.625195
0.00866
P30519,Q07065,P61225,O60784,Q08722,P27105
Localization
GO Cellular component
msigdb_gocc
35,196,204,268,177,181
2443,299,924,753,268,181,35,204,196,177,881,2635,1191,836,667,1918,940,1342
-0.7187857872122325,1.3249255008810943,0.2925877034989214,0.5072645015459241,1.4340378681739008,1.7305705557513118,2.874368785321353,1.615606089441541,1.6471520721581714,1.7409268040090475,0.3564547613061034,-0.8705242595411103,0.05739652070350504,0.40710747145539755,0.6059317074422123,-0.39706930245536326,0.2925877034989214,-0.04990220374204181
3,040
Mental deterioration
50
102
2.625052
0.008664
O43464,Q13057,Q86SQ9,O60220,P07602,P54802,Q9NZJ7,Q9BQE5,P36543,Q9H2C2,Q14108,Q10713,P00846,P50897,P61916,P35637,O95140,P16278,Q9UHD9,O95470,Q96RR1,P17900,P04350,Q96RL7,P04062,Q13510,P21912,O75503,O43681,P03886,O76024,O60313,P10644,O00429,P21964,Q9Y487,P22626,O75306,Q03164,Q9NPL8,Q6PI48,Q06787,O96008,P04080,Q9NQZ5,P06865,Q9UBB4,Q5XKP0,P05067,O15118
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
628,765,134,264,266,384,138,11,773,398,272,279,22,27,410,289,796,294,558,168,556,169,672,696,180,54,565,190,700,195,323,455,592,468,86,91,473,481,746,484,749,757,489,613,113,246,638,122,126,255
468,255,628,700,795,264,455,1384,2706,481,190,323,796,2389,168,489,928,22,195,180,613,672,126,246,266,1520,3024,2724,903,2611,592,294,2803,169,1135,1225,565,86,473,2665,843,2168,931,289,773,1989,1780,2392,1203,2919,27,2549,2859,384,1637,1583,410,1811,2416,746,2208,2209,2050,757,2738,279,765,1391,54,272,1703,2557,1332,122,2239,749,1169,134,1234,985,2891,986,2636,1708,696,556,2981,2125,2989,11,2093,2224,398,484,113,2678,138,638,2268,558,980,91
0.9051741409295114,1.466432896979965,0.6425575843066014,0.5691030270776883,0.45737527732568883,1.444853358337915,0.9285450565881448,-0.09059771360529514,-0.9322432477268474,0.8817214834855824,1.6785532275719157,1.247488927312642,0.45737527732568883,-0.67395649066749,1.7821961261129045,0.8699643062088395,0.2925877034989214,3.0993713176235196,1.6576351441981245,1.7305705557513118,0.6668633638533525,0.5936781351799993,2.0048528443378144,1.4879442405996233,1.444853358337915,-0.18655323709370267,-2.611073039938298,-0.9477668055435992,0.3182087393302986,-0.8551873385144706,0.7031565908693913,1.3359159947113879,-1.0417117055833216,1.7821961261129045,0.09718452280470133,0.030736330125996712,0.7392533700796472,2.3164237833166905,0.8934580688928646,-0.9013091013207586,0.39448062923729826,-0.5413153919519684,0.2925877034989214,1.3578437107911476,0.4823668232401796,-0.4400058576962713,-0.326135443565647,-0.67395649066749,0.04407999074490389,-1.2664819236308702,2.979105090473296,-0.7942051683058742,-1.1370667422921092,1.0785056180895356,-0.25596938782450307,-0.22811391955386917,1.0097084148679092,-0.34026020681916364,-0.6888648126817407,0.5196783799645482,-0.5559189875116972,-0.5559189875116972,-0.46878952976590854,0.5072645015459241,-0.9633282872250349,1.40148779769058,0.49482734776906995,-0.09059771360529514,2.532046451483146,1.4232051513701809,-0.28394483378593255,-0.7942051683058742,-0.04990220374204181,2.0445744152136456,-0.5705557698197767,0.5196783799645482,0.07068604002806808,1.9347852868226298,0.030736330125996712,0.2280960394572554,-1.201443286855556,0.2280960394572554,-0.8705242595411103,-0.28394483378593255,0.581401938827193,0.7632098916182667,-1.5677651074261831,-0.5122071076002075,-1.6367289091365962,3.3914306381259736,-0.497702095159616,-0.5559189875116972,1.055651255437339,0.8817214834855824,2.1233394389583222,-0.9013091013207586,1.9347852868226298,0.6425575843066014,-0.5852259038097922,0.7632098916182667,0.2410449813533824,2.28780100884114
3,040
Vacuole organization
21
55
2.616
0.008897
Q86Y82,Q14108,O75396,P10253,P50897,O14773,P11117,Q9UHD9,P04062,O75503,Q676U5,P56962,Q96GC9,P16615,Q8N511,Q9P253,Q9HC07,Q8NEB9,Q9Y371,Q9H0U4,P54802
Processes and pathways
GO Biological process
msigdb_gobp
506,272,527,400,27,283,288,558,180,190,66,450,79,336,213,480,97,105,639,510,384
1309,283,910,527,190,796,1745,877,2082,180,2408,1520,400,288,336,1961,721,2693,27,1019,1167,384,450,1607,845,1151,272,631,1287,66,1191,675,3031,2437,506,213,105,1290,775,1465,79,2076,1708,510,1710,1741,1621,97,480,558,1847,1380,1551,639,1382
-0.03639319191522044,1.37970081375604,0.30541065998888134,0.7989843584173286,1.6785532275719157,0.45737527732568883,-0.31204139030411787,0.3564547613061034,-0.497702095159616,1.7305705557513118,-0.6888648126817407,-0.18655323709370267,1.0441949184190364,1.3578437107911476,1.2252005430134607,-0.4256619663333324,0.5444366893129593,-0.9167574127737401,2.979105090473296,0.18909564139474644,0.07068604002806808,1.0785056180895356,0.9402000549206043,-0.24202672664337113,0.39448062923729826,0.0839486679282727,1.4232051513701809,0.6425575843066014,-0.009458648363643903,2.4671241214659725,0.05739652070350504,0.5936781351799993,-4.288396656099267,-0.7038078525879563,0.8345684311908745,1.583913814546594,2.1915315517867935,-0.009458648363643903,0.4823668232401796,-0.1452562941458644,2.354405332523084,-0.4832296221450455,-0.28394483378593255,0.8345684311908745,-0.28394483378593255,-0.2979779017776956,-0.24202672664337113,2.239833036702955,0.8934580688928646,0.7632098916182667,-0.35441582638841634,-0.07700433730373651,-0.20037731236087014,0.6425575843066014,-0.07700433730373651
3,040
Abnormal circulating lipid concentration
36
74
2.61528
0.008915
Q15904,P07602,Q9NZJ7,P31751,P23786,Q9Y6B6,Q9BTV4,O43826,P50402,O75880,Q9BV10,Q15392,P61916,P06280,O95470,P40939,O75844,Q9NVI7,O75381,P50416,P28070,Q15125,O75431,Q9Y4P3,Q8N511,Q10471,P37268,Q9H9E3,P40855,Q9UJS0,Q15800,Q13045,Q14739,Q9Y5Y5,P50542,Q16836
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
643,266,138,772,140,657,655,405,534,407,149,150,410,292,168,688,59,577,318,583,203,712,707,206,213,600,475,612,229,621,109,758,116,516,755,250
1455,1367,1850,925,405,318,707,806,59,407,168,2144,292,1630,266,1106,3018,1408,140,203,1631,772,1749,2320,475,2988,229,688,2392,969,1227,2302,534,583,755,2549,1427,2777,2550,786,410,2646,2907,1209,600,758,1752,116,1912,712,150,2814,109,643,250,213,1192,2491,1042,919,655,149,1024,612,577,138,1653,2789,621,1006,206,2227,516,657
-0.1452562941458644,-0.07700433730373651,-0.36860244967466754,0.2925877034989214,1.0327190479133637,1.2586056494763058,0.5567813080560997,0.4448440621115383,2.5042963521150807,1.0212235711320679,1.7821961261129045,-0.5267448194609747,1.3468887104804244,-0.25596938782450307,1.444853358337915,0.12357638308743593,-2.1988432298536535,-0.10421946745368259,1.9146345006853838,1.615606089441541,-0.25596938782450307,0.4823668232401796,-0.31204139030411787,-0.6294380842913514,0.8934580688928646,-1.6367289091365962,1.5307642110055628,0.581401938827193,-0.67395649066749,0.25396851053519315,0.030736330125996712,-0.6146668929180736,0.7870808006365844,0.7152105634749184,0.5072645015459241,-0.7942051683058742,-0.1178697283777986,-1.010242310415109,-0.7942051683058742,0.4698828319614009,1.0097084148679092,-0.8858981156239302,-1.2338789162429935,0.04407999074490389,0.6910807910791582,0.5072645015459241,-0.31204139030411787,2.0939075243292486,-0.39706930245536326,0.5567813080560997,1.8639980435174222,-1.0417117055833216,2.162388458299299,0.6303713421013281,1.4771970637826917,1.583913814546594,0.05739652070350504,-0.7488470548949705,0.1760439488988051,0.30541065998888134,0.6181627463554006,1.87415518169426,0.18909564139474644,0.678983077713463,0.7272427947625875,1.9347852868226298,-0.25596938782450307,-1.010242310415109,0.6668633638533525,0.21512157560145628,1.6050583254928277,-0.5559189875116972,0.8345684311908745,0.6181627463554006
3,040