term stringlengths 2 121 | overlap int64 6 281 | setsize int64 7 499 | score float64 1.96 10.6 | pval float64 0 0.05 | edge stringlengths 41 1.97k | type stringclasses 5 values | subtype stringclasses 24 values | subtype_key stringclasses 24 values | edge_idxs stringlengths 11 1.17k | ann_idxs stringlengths 19 2.31k | ann_vals stringlengths 124 9.94k | sig_size int64 2.2k 3.73k |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Fatty acid metabolism | 17 | 42 | 1.99085 | 0.046497 | O00767,P11310,Q9UJ83,P09110,P30084,Q13085,Q9BV79,O00763,P45954,P51648,O60488,O00154,O95864,P42765,Q9NZ01,Q14914,P33121 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 153,3,131,191,539,71,101,45,477,273,269,267,425,334,365,94,399 | 2174,267,45,153,269,1522,1930,425,191,3,1038,1321,1231,539,399,2851,1786,1418,334,477,898,273,545,1239,1003,3039,71,94,725,679,2405,1741,2408,2489,1200,101,2992,1449,365,1021,131,1968 | -0.38840907164402044,1.0239895379527157,2.2424648938387963,1.3590061371467457,1.0239895379527157,-0.004489969793840124,-0.22629185139669705,0.7677859154269809,1.2566581818453404,6.730885687037684,0.2826136382253935,0.10898207923474212,0.1663929125036829,0.6432554209821486,0.7992795222044343,-1.295705443571504,-0.14389505534583355,0.0520243002597027,0.8946563157455603,0.705235470611286,0.3710446118356444,1.0239895379527157,0.6432554209821486,0.1663929125036829,0.311967859991844,-7.255540063846335,1.9726151997856707,1.7859572386753468,0.49071115338267796,0.5209516142505475,-0.5471262019754356,-0.11622456163007196,-0.5471262019754356,-0.6252686065305768,0.1952712998201284,1.7127411542268645,-2.326200077911209,0.0520243002597027,0.8627128038292345,0.311967859991844,1.4980975591350763,-0.22629185139669705 | 3,042 |
WD40/YVTN repeat-like-containing domain superfamily [IPR015943] | 37 | 95 | 1.990527 | 0.046533 | Q9Y263,O94979,O75083,Q9HAD4,Q92747,Q9Y4P8,Q13347,Q12834,Q9BR76,Q9HC35,Q9Y5J1,Q9HCU5,Q9GZL7,P57081,P78406,P63244,P53621,Q9NVX2,O75717,Q8TEQ6,Q6UXN9,P61964,Q969X6,P55884,Q9BQA1,Q9Y3F4,Q96DI7,O43172,P54198,O60508,Q9BV38,Q9Y4B6,Q9ULV4,Q9NRG9,Q14137,O43660,Q9BY44 | Sequence | InterPro Superfamily | interpro_homologous_superfamily | 659,370,631,138,410,17,405,404,289,562,695,688,557,30,33,172,547,304,665,321,196,315,733,581,76,216,213,698,580,217,498,241,239,385,647,242,654 | 2627,2248,1970,1267,698,242,1121,2285,2251,1030,217,631,882,665,370,1064,1177,1894,1367,1183,547,580,581,30,1326,1371,315,854,172,33,2991,1334,1287,404,1687,405,1801,1088,1994,647,2371,2485,1855,2037,1092,1011,2786,771,1543,1296,196,2229,2193,1099,1589,2621,1194,1700,321,2085,2536,410,733,213,1592,923,2961,971,76,289,1654,498,654,2636,1396,557,2088,138,562,688,1558,385,304,2090,934,239,1713,2321,659,830,216,241,1060,17,695 | -0.804597676954388,-0.44168301553792116,-0.2535559445516243,0.13763025442627902,0.49071115338267796,1.0896210596823075,0.224266685004557,-0.46818060274790824,-0.44168301553792116,0.2826136382253935,1.1893243998026075,0.5513246708384371,0.3710446118356444,0.5209516142505475,0.8309211854963305,0.25338035951760995,0.1952712998201284,-0.19892767510057235,0.08044716231296069,0.1952712998201284,0.6432554209821486,0.6124749421328806,0.6124749421328806,2.5627549696437755,0.10898207923474212,0.08044716231296069,0.9267537009827378,0.4007699452361339,1.3247070472419966,2.522036392555912,-2.326200077911209,0.10898207923474212,0.13763025442627902,0.7992795222044343,-0.08844988349688336,0.7992795222044343,-0.14389505534583355,0.25338035951760995,-0.2535559445516243,0.5513246708384371,-0.5209013476638797,-0.6252686065305768,-0.1714624153297538,-0.2807209388587076,0.25338035951760995,0.311967859991844,-1.1028434179300095,0.46060173357485173,-0.004489969793840124,0.13763025442627902,1.2566581818453404,-0.41509279897078943,-0.38840907164402044,0.25338035951760995,-0.03258368300213388,-0.7792298249850403,0.1952712998201284,-0.08844988349688336,0.9267537009827378,-0.3077878029256116,-0.6769280959291052,0.7992795222044343,0.49071115338267796,1.2229031754359916,-0.03258368300213388,0.3710446118356444,-1.9595816524913425,0.34144438829038104,1.9348733767796076,0.9914182237351489,-0.06056995269590213,0.705235470611286,0.5513246708384371,-0.804597676954388,0.08044716231296069,0.6432554209821486,-0.3077878029256116,1.428167182252151,0.6432554209821486,0.5209516142505475,-0.004489969793840124,0.8309211854963305,0.9590069816971801,-0.3077878029256116,0.3710446118356444,1.122685726570218,-0.08844988349688336,-0.46818060274790824,0.5513246708384371,0.430621829668562,1.2229031754359916,1.122685726570218,0.2826136382253935,3.28399380554636,0.5209516142505475 | 3,042 |
Epidermal acanthosis | 6 | 13 | 1.98945 | 0.046652 | P20810,Q06136,P50452,P14923,P15924,Q14574 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 225,195,133,111,142,27 | 1408,537,111,142,243,225,3005,133,1374,195,27,2408,783 | 0.0520243002597027,0.6432554209821486,1.6403619289797706,1.3934919236740546,1.0896210596823075,1.155919387412329,-2.678362897278987,1.4630347562163608,0.08044716231296069,1.2566581818453404,2.6036665175292217,-0.5471262019754356,0.46060173357485173 | 3,042 |
Cell junction assembly | 17 | 69 | 1.983258 | 0.047339 | P41440,O14786,O14920,P62330,O75116,Q9Y624,Q9P258,Q9Y2S7,P17612,P51153,Q9ULV4,Q15375,P36404,P14923,P61586,O75122,Q00535 | Processes and pathways | GO Biological process | msigdb_gobp | 0,189,134,41,505,152,78,419,451,457,239,486,234,111,122,421,249 | 602,1773,189,134,2248,2017,2285,2178,631,505,421,1928,2956,2875,2255,111,451,1838,706,2711,2143,1414,234,0,1531,1895,1843,457,511,899,2431,1484,2996,1004,122,41,676,1144,249,1685,2074,1799,1687,1993,2462,1853,1739,486,1691,1638,649,2159,1504,1256,1552,1751,2165,1878,2314,929,78,2319,239,2386,1767,419,1214,3031,152 | 0.5818319081050546,-0.14389505534583355,1.2566581818453404,1.428167182252151,-0.44168301553792116,-0.2807209388587076,-0.46818060274790824,-0.38840907164402044,0.5513246708384371,0.6741750255750224,0.7677859154269809,-0.22629185139669705,-1.91542288944853,-1.3668723575132662,-0.44168301553792116,1.6403619289797706,0.7364385055169148,-0.1714624153297538,0.49071115338267796,-0.930227147207571,-0.3616309383984686,0.0520243002597027,1.122685726570218,9.698212226956453,-0.004489969793840124,-0.19892767510057235,-0.1714624153297538,0.7364385055169148,0.6741750255750224,0.3710446118356444,-0.5732618206856096,0.023712310382377713,-2.4312084389974737,0.311967859991844,1.5333585772385927,2.321360999324158,0.5209516142505475,0.224266685004557,1.0896210596823075,-0.08844988349688336,-0.3077878029256116,-0.14389505534583355,-0.08844988349688336,-0.2535559445516243,-0.5993090206318084,-0.1714624153297538,-0.11622456163007196,0.705235470611286,-0.08844988349688336,-0.06056995269590213,0.5513246708384371,-0.3616309383984686,0.023712310382377713,0.1663929125036829,-0.004489969793840124,-0.11622456163007196,-0.3616309383984686,-0.1714624153297538,-0.46818060274790824,0.3710446118356444,1.9348733767796076,-0.46818060274790824,1.122685726570218,-0.5209013476638797,-0.11622456163007196,0.7992795222044343,0.1952712998201284,-4.334858416461321,1.3934919236740546 | 3,042 |
Leukodystrophy | 24 | 53 | 1.982858 | 0.047383 | O95169,Q9P0J0,O95299,O14802,Q86SX6,P19404,Q16795,P30084,Q4G0N4,O43676,Q15046,O75251,Q7KZN9,Q15067,P49821,P08559,P11498,O75306,Q9BU61,P04350,P07814,Q9BSH4,Q9NPL8,Q6PI48 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 371,531,132,742,275,397,550,539,812,662,809,790,56,725,62,312,205,202,497,606,232,256,784,523 | 1357,742,1519,662,2095,1925,790,202,988,1719,371,132,1169,2924,606,2289,232,312,1412,205,397,2694,1037,1982,539,800,1369,62,1141,1424,2220,1686,1288,809,725,1294,550,812,523,56,275,1193,1017,1393,921,256,497,784,1827,2278,531,2641,2951 | 0.08044716231296069,0.46060173357485173,-0.004489969793840124,0.5209516142505475,-0.334757490018813,-0.22629185139669705,0.430621829668562,1.2229031754359916,0.311967859991844,-0.11622456163007196,0.8309211854963305,1.4630347562163608,0.1952712998201284,-1.6455961576279343,0.5818319081050546,-0.46818060274790824,1.122685726570218,0.9267537009827378,0.0520243002597027,1.2229031754359916,0.7992795222044343,-0.9052602538909462,0.2826136382253935,-0.2535559445516243,0.6432554209821486,0.430621829668562,0.08044716231296069,2.0870588752028905,0.224266685004557,0.0520243002597027,-0.41509279897078943,-0.08844988349688336,0.13763025442627902,0.430621829668562,0.49071115338267796,0.13763025442627902,0.6432554209821486,0.430621829668562,0.6741750255750224,2.1256103094361922,1.0239895379527157,0.1952712998201284,0.311967859991844,0.08044716231296069,0.3710446118356444,1.0896210596823075,0.705235470611286,0.46060173357485173,-0.14389505534583355,-0.44168301553792116,0.6741750255750224,-0.804597676954388,-1.8040272703548432 | 3,042 |
Regulation of endocytosis | 13 | 49 | 1.981922 | 0.047488 | P41440,Q99816,Q15036,Q96PU5,Q8IYB5,P62330,Q06787,P49815,P51148,Q4KMQ2,Q13614,Q08209,Q96CW1 | Processes and pathways | GO Biological process | msigdb_gobp | 0,496,519,264,440,41,340,75,456,147,484,585,29 | 1883,1773,1928,2956,1570,2428,2831,1892,1035,1724,993,2885,0,75,2104,3009,456,1325,1989,1004,582,2749,41,676,1332,2075,340,2684,585,1189,484,1633,519,2037,147,1643,440,1298,2084,29,264,496,1955,1205,1457,1962,1355,1963,2520 | -0.19892767510057235,-0.14389505534583355,-0.22629185139669705,-1.91542288944853,-0.03258368300213388,-0.5732618206856096,-1.2239161561410112,-0.19892767510057235,0.2826136382253935,-0.11622456163007196,0.311967859991844,-1.4139783306185167,9.698212226956453,1.9348733767796076,-0.334757490018813,-2.8195154670502323,0.7364385055169148,0.10898207923474212,-0.2535559445516243,0.311967859991844,0.6124749421328806,-1.0046615449094627,2.321360999324158,0.5209516142505475,0.10898207923474212,-0.3077878029256116,0.8946563157455603,-0.8802145418906248,0.6124749421328806,0.1952712998201284,0.705235470611286,-0.06056995269590213,0.6741750255750224,-0.2807209388587076,1.3934919236740546,-0.06056995269590213,0.7677859154269809,0.13763025442627902,-0.3077878029256116,2.6036665175292217,1.0567230815871713,0.705235470611286,-0.22629185139669705,0.1952712998201284,0.0520243002597027,-0.22629185139669705,0.10898207923474212,-0.22629185139669705,-0.6511413712255735 | 3,042 |
Organic acid catabolic process | 17 | 76 | 1.971253 | 0.048695 | Q8IYS1,Q96RQ3,P11310,Q9UJ83,P09110,Q9NTX5,O75521,O00763,P05165,O43808,Q6YP21,P14550,P35610,Q6NVY1,O15382,P11182,P25325 | Processes and pathways | GO Biological process | msigdb_gobp | 198,97,3,131,191,104,135,45,167,291,210,296,51,286,120,93,157 | 2174,45,120,2936,291,135,1031,474,1122,1835,1223,167,1171,191,2569,1226,93,3,946,296,2099,1528,992,1131,1038,1321,157,1231,1529,539,3005,751,711,1619,1135,51,1574,1076,1416,1786,1418,334,477,1481,2780,433,545,671,1003,1536,1043,3039,587,725,2838,2533,1857,2405,1741,286,2408,210,2739,198,2489,778,97,1200,1202,1597,687,1511,104,1459,2732,131 | -0.38840907164402044,2.2424648938387963,1.5333585772385927,-1.7364888634210678,0.9590069816971801,1.428167182252151,0.2826136382253935,0.705235470611286,0.224266685004557,-0.1714624153297538,0.1663929125036829,1.3247070472419966,0.1952712998201284,1.2566581818453404,-0.72824649345985,0.1663929125036829,1.7859572386753468,6.730885687037684,0.34144438829038104,0.9590069816971801,-0.334757490018813,-0.004489969793840124,0.311967859991844,0.224266685004557,0.2826136382253935,0.10898207923474212,1.3590061371467457,0.1663929125036829,-0.004489969793840124,0.6432554209821486,-2.678362897278987,0.46060173357485173,0.49071115338267796,-0.06056995269590213,0.224266685004557,2.164362275576657,-0.03258368300213388,0.25338035951760995,0.0520243002597027,-0.14389505534583355,0.0520243002597027,0.8946563157455603,0.705235470611286,0.023712310382377713,-1.0784100654685373,0.7677859154269809,0.6432554209821486,0.5209516142505475,0.311967859991844,-0.004489969793840124,0.2826136382253935,-7.255540063846335,0.6124749421328806,0.49071115338267796,-1.2479159821538457,-0.6769280959291052,-0.1714624153297538,-0.5471262019754356,-0.11622456163007196,0.9914182237351489,-0.5471262019754356,1.2229031754359916,-0.9799271388310594,1.2566581818453404,-0.6252686065305768,0.46060173357485173,1.7492450119236242,0.1952712998201284,0.1952712998201284,-0.03258368300213388,0.5209516142505475,0.023712310382377713,1.7127411542268645,0.0520243002597027,-0.9551158893931155,1.4980975591350763 | 3,042 |
Regulation of cell substrate junction organization | 9 | 22 | 1.966086 | 0.049289 | O14786,Q15555,P62330,O75116,Q9P258,Q9ULV4,Q9Y2S7,O75122,P61586 | Processes and pathways | GO Biological process | msigdb_gobp | 189,36,41,505,78,239,419,421,122 | 189,505,421,1838,1843,511,2996,122,41,676,1144,2074,36,2159,1256,1878,929,78,239,2386,2469,419 | 1.2566581818453404,0.6741750255750224,0.7677859154269809,-0.1714624153297538,-0.1714624153297538,0.6741750255750224,-2.4312084389974737,1.5333585772385927,2.321360999324158,0.5209516142505475,0.224266685004557,-0.3077878029256116,2.4815114338388424,-0.3616309383984686,0.1663929125036829,-0.1714624153297538,0.3710446118356444,1.9348733767796076,1.122685726570218,-0.5209013476638797,-0.5993090206318084,0.7992795222044343 | 3,042 |
Electron transfer activity | 22 | 52 | 1.962146 | 0.049746 | O95169,Q9P0J0,O95299,P05091,O75438,P19404,P31930,Q16795,O43488,Q6FI81,P51970,Q7KZN9,P03915,P49821,P08574,P48163,O43837,P15121,O95182,O75306,O15460,P11766 | Functions | GO Molecular function | msigdb_gomf | 371,531,132,635,16,397,143,550,392,680,546,56,311,62,572,193,567,573,328,202,115,117 | 1357,115,744,392,662,567,790,202,16,988,884,371,328,132,1169,1034,1977,2924,311,635,572,2569,2216,117,2139,946,3002,573,2024,397,1318,1037,890,1131,1982,800,143,1416,193,62,546,1377,764,1294,2838,2189,550,680,56,531,933,2951 | 0.08044716231296069,1.568820871956387,0.46060173357485173,0.7992795222044343,0.5209516142505475,0.6124749421328806,0.430621829668562,1.2229031754359916,3.3280933866218882,0.311967859991844,0.3710446118356444,0.8309211854963305,0.8946563157455603,1.4630347562163608,0.1952712998201284,0.2826136382253935,-0.2535559445516243,-1.6455961576279343,0.9267537009827378,0.5513246708384371,0.6124749421328806,-0.72824649345985,-0.41509279897078943,1.568820871956387,-0.3616309383984686,0.34144438829038104,-2.5556249228754946,0.6124749421328806,-0.2807209388587076,0.7992795222044343,0.10898207923474212,0.2826136382253935,0.3710446118356444,0.224266685004557,-0.2535559445516243,0.430621829668562,1.3934919236740546,0.0520243002597027,1.2566581818453404,2.0870588752028905,0.6432554209821486,0.08044716231296069,0.46060173357485173,0.13763025442627902,-1.2479159821538457,-0.38840907164402044,0.6432554209821486,0.5209516142505475,2.1256103094361922,0.6741750255750224,0.3710446118356444,-1.8040272703548432 | 3,042 |
Lysosome | 24 | 55 | 3.973713 | 0.000071 | Q99519,Q9NZJ7,Q14108,P20645,P50897,Q9Y487,O75503,Q15012,P54802,Q8NHS3,Q13510,Q9UMR5,O15118,P61916,P04062,P10619,P17900,P16278,Q8NCC3,P07858,P06280,P11117,P07602,Q93050 | Processes and pathways | KEGG Pathways | msigdb_kegg | 132,275,20,282,27,156,158,32,161,37,40,176,51,308,56,185,186,65,89,223,231,240,113,121 | 553,2345,623,383,1214,624,51,625,1667,158,56,454,231,386,113,2598,223,596,629,1559,573,185,240,559,1508,982,65,186,282,2898,27,1127,161,1470,308,1792,516,40,20,32,318,89,37,1237,121,132,1355,2107,2765,275,2209,728,176,1143,156 | 0.5203652040028177,-0.5254772864924734,0.4269371803541035,0.7929611203043013,-0.021142844948492293,0.4269371803541035,3.0329755799706857,0.4269371803541035,-0.2263016271137345,1.8013490730391473,2.861170882369116,0.6671420469276572,1.3401101108679196,0.7929611203043013,2.2493125713395874,-0.6807859438462549,1.3892463318502195,0.464468695655408,0.4269371803541035,-0.18472611797839597,0.5017859632503069,1.6299048673842986,1.2906252596776078,0.5203652040028177,-0.16404228682087726,0.13829633186814977,2.739955797601633,1.6299048673842986,1.123076264470747,-1.0758316877354026,3.5515088405121995,0.039118345533642226,1.7859314470019894,-0.14342697267853247,1.0205517659257686,-0.2681581692824456,0.5757898109834075,3.162609148347032,3.863819674290911,3.390720955781931,0.9860318695770233,2.477570524290023,3.2010864353849686,-0.021142844948492293,2.1911393985906495,2.0585502205371826,-0.08198652438815046,-0.3954626277985668,-0.8172019719548473,1.1569131412555997,-0.4384926181619229,0.3512189297429039,1.6770712269532793,0.039118345533642226,1.8167337774526302 | 3,053 |
Sphingolipid metabolic process | 21 | 35 | 3.939076 | 0.000082 | Q99805,Q99519,Q16739,Q96G23,Q9NZJ7,P50897,P27544,Q13510,Q8TCT0,P04062,P17900,Q9H2C2,O95470,P16278,Q9P035,Q8NCC3,Q06136,P06280,P07602,Q9NZ01,Q9NRX5 | Processes and pathways | GO Biological process | msigdb_gobp | 128,132,136,11,275,27,159,40,169,56,186,192,61,65,218,89,102,231,113,115,124 | 295,1451,872,61,56,231,386,113,2598,65,186,1335,1832,159,1032,27,2539,102,2365,40,136,549,89,169,2200,11,132,128,192,124,998,115,275,218,2389 | 1.0720060894912629,-0.14342697267853247,0.21654186145358403,2.780573201657302,2.861170882369116,1.3401101108679196,0.7929611203043013,2.2493125713395874,-0.6807859438462549,2.739955797601633,1.6299048673842986,-0.08198652438815046,-0.28919332161258265,1.7859314470019894,0.09881078799017154,3.5515088405121995,-0.6360002154493802,2.3500331786247033,-0.5254772864924734,3.162609148347032,1.998844642307609,0.5388920140603658,2.477570524290023,1.7239281707505134,-0.4384926181619229,4.266395697843969,2.0585502205371826,2.1177736122329143,1.6141131009311325,2.1765244342071473,0.13829633186814977,2.2348120000348723,1.1569131412555997,1.4380399974777385,-0.5254772864924734 | 3,053 |
Steroid metabolic process | 23 | 65 | 3.917854 | 0.000089 | Q06520,P35610,P05023,Q9UBM7,Q8WTV0,Q53GQ0,Q15392,Q14849,Q13510,Q14739,O15118,P61916,Q14534,P04062,Q16850,Q9H2C2,O95470,Q9BQE5,P16435,P34913,P37268,Q15800,P38435 | Processes and pathways | GO Biological process | msigdb_gobp | 4,258,264,269,26,283,29,30,40,41,51,308,183,56,60,192,61,63,323,325,197,95,107 | 51,2175,61,1826,2501,56,571,264,847,2465,2528,1297,1259,1828,323,1832,2078,2533,2403,694,325,258,197,107,2898,2267,326,2505,1099,1743,308,618,2277,2680,2920,1104,4,40,2574,183,41,30,885,1914,29,2708,1629,2280,95,60,283,1483,590,26,2894,1284,2107,2712,63,2492,192,269,2648,1715,1983 | 3.0329755799706857,-0.4384926181619229,2.780573201657302,-0.28919332161258265,-0.6137324247371202,2.861170882369116,0.5017859632503069,1.1905844892407613,0.23595476382188807,-0.5915469880276591,-0.6360002154493802,-0.061639706843019025,-0.04135865661767714,-0.28919332161258265,0.9687059891173524,-0.28919332161258265,-0.3954626277985668,-0.6360002154493802,-0.5474201594629304,0.3702313895262678,0.9687059891173524,1.2073587193318431,1.5505926056196673,2.307033723210691,-1.0758316877354026,-0.48182900048661537,0.9687059891173524,-0.6137324247371202,0.05907835699925959,-0.24719447231895844,1.0205517659257686,0.4457299111164649,-0.48182900048661537,-0.7486017803237077,-1.1241192412166017,0.05907835699925959,4.564311687934693,3.162609148347032,-0.6583511285219581,1.645661682349741,3.162609148347032,3.428112577652922,0.21654186145358403,-0.31030054118727124,3.4405377784263176,-0.7713802427604488,-0.20547903817502652,-0.48182900048661537,2.392786822066208,2.794064797575269,1.123076264470747,-0.14342697267853247,0.4831539193642934,3.588162517641911,-1.0518387672424332,-0.04135865661767714,-0.3954626277985668,-0.7713802427604488,2.7670579060311247,-0.5915469880276591,1.6141131009311325,1.1737693798534528,-0.7033054530869399,-0.2263016271137345,-0.3314804483105227 | 3,053 |
Active transmembrane transporter activity | 32 | 73 | 3.850209 | 0.000118 | P12235,P05023,O75489,O95202,P53985,O00400,Q9UBX3,Q7KZN9,P03886,P20674,Q03518,P03915,P04920,O43676,P16615,O95168,P12236,Q8NE86,O75306,P36543,Q9P0J0,P20020,P13073,Q9HD20,Q9Y6M7,Q96ES6,Q9UDW1,P08183,P41440,Q15526,P05141,O75438 | Functions | GO Molecular function | msigdb_gomf | 257,264,384,148,403,154,36,43,45,421,424,304,305,47,436,434,188,452,195,456,203,331,330,211,487,91,92,349,362,244,377,126 | 154,952,1250,47,1369,1177,195,126,384,434,628,1604,148,978,595,691,45,304,305,264,377,1731,349,1125,614,1507,257,188,330,436,1831,331,421,1462,2264,694,3014,828,456,2472,362,2183,927,1152,783,1101,403,1010,1470,648,531,424,757,1389,1105,244,1630,2413,650,43,452,1704,91,498,1244,793,211,203,36,92,2209,487,1053 | 1.8167337774526302,0.15794771197129795,-0.04135865661767714,3.072090978975674,-0.10239964490688236,-0.0009917498407377972,1.566526139717696,2.1618805177312446,0.7929611203043013,0.7033333538782307,0.4269371803541035,-0.20547903817502652,1.893169553532986,0.13829633186814977,0.464468695655408,0.3702313895262678,3.0850861706306985,1.0377463366595439,1.0377463366595439,1.1905844892407613,0.8107434624970358,-0.24719447231895844,0.8989563120030468,0.039118345533642226,0.4457299111164649,-0.16404228682087726,1.2073587193318431,1.6141131009311325,0.9513357791761082,0.7033333538782307,-0.28919332161258265,0.9513357791761082,0.7213554512800274,-0.14342697267853247,-0.48182900048661537,0.3702313895262678,-1.959204894557855,0.255309170150584,0.6671420469276572,-0.5915469880276591,0.8638097235543348,-0.4384926181619229,0.17753878759272398,0.019095144049973707,0.29384424374464585,0.05907835699925959,0.7572541827182976,0.11858418117435018,-0.14342697267853247,0.40809011351908236,0.5573667616763491,0.7213554512800274,0.31302577253021713,-0.10239964490688236,0.05907835699925959,1.2740517609654562,-0.20547903817502652,-0.5474201594629304,0.40809011351908236,3.149741568733179,0.6852623302074585,-0.2263016271137345,2.4352981359162196,0.612482250975132,-0.021142844948492293,0.29384424374464585,1.4703817232301912,1.5186175105719402,3.213870662525028,2.4352981359162196,-0.4384926181619229,0.6307523498834328,0.09881078799017154 | 3,053 |
Membrane lipid metabolic process | 22 | 45 | 3.845507 | 0.00012 | Q99805,Q99519,Q16739,Q96G23,Q9NZJ7,P50897,P27544,Q13510,Q8TCT0,P04062,P17900,Q9H2C2,O95470,P16278,Q9P035,Q8NCC3,Q06136,P06280,Q9H490,P07602,Q9NZ01,Q9NRX5 | Processes and pathways | GO Biological process | msigdb_gobp | 128,132,136,11,275,27,159,40,169,56,186,192,61,65,218,89,102,231,106,113,115,124 | 295,1451,729,872,1775,61,56,454,231,386,113,2598,65,186,1335,1832,159,1032,1895,27,2539,102,2365,40,136,549,451,89,169,2200,944,2823,11,2584,132,862,128,192,106,124,998,115,275,218,2389 | 1.0720060894912629,-0.14342697267853247,0.3321505284860475,0.21654186145358403,-0.2681581692824456,2.780573201657302,2.861170882369116,0.6671420469276572,1.3401101108679196,0.7929611203043013,2.2493125713395874,-0.6807859438462549,2.739955797601633,1.6299048673842986,-0.08198652438815046,-0.28919332161258265,1.7859314470019894,0.09881078799017154,-0.31030054118727124,3.5515088405121995,-0.6360002154493802,2.3500331786247033,-0.5254772864924734,3.162609148347032,1.998844642307609,0.5388920140603658,0.6852623302074585,2.477570524290023,1.7239281707505134,-0.4384926181619229,0.17753878759272398,-0.9099290428795153,4.266395697843969,-0.6583511285219581,2.0585502205371826,0.23595476382188807,2.1177736122329143,1.6141131009311325,2.3213944057139972,2.1765244342071473,0.13829633186814977,2.2348120000348723,1.1569131412555997,1.4380399974777385,-0.5254772864924734 | 3,053 |
Cation transmembrane transporter activity | 31 | 72 | 3.822842 | 0.000132 | P12235,P05023,O95202,Q9Y487,O00400,O75964,Q4KMQ2,Q7KZN9,P20674,Q8NEW0,Q8IUH4,P16615,Q8NE86,Q9HC07,P36543,P20020,P13073,Q9HD20,Q9HC21,Q13423,Q9Y6M7,P30825,Q96ES6,Q9UDW1,Q9Y619,P24539,O43772,Q15526,Q93050,Q70HW3,P05141 | Functions | GO Molecular function | msigdb_gomf | 257,264,148,156,154,35,296,43,421,49,184,436,452,196,456,331,330,211,339,88,487,214,91,92,365,238,241,244,121,251,377 | 154,241,690,977,35,148,691,264,377,1731,1055,2895,2353,1125,614,1507,257,330,436,331,421,1462,2264,238,2656,214,828,1222,456,2472,2776,927,1010,830,1063,1470,733,648,588,757,88,1389,244,1630,296,251,43,184,550,452,49,1704,1972,121,91,890,498,1023,1244,769,793,727,196,339,211,814,92,2209,1546,156,365,487 | 1.8167337774526302,1.2740517609654562,0.3702313895262678,0.13829633186814977,3.2266342617272703,1.893169553532986,0.3702313895262678,1.1905844892407613,0.8107434624970358,-0.24719447231895844,0.07897567452569614,-1.0758316877354026,-0.5254772864924734,0.039118345533642226,0.4457299111164649,-0.16404228682087726,1.2073587193318431,0.9513357791761082,0.7033333538782307,0.9513357791761082,0.7213554512800274,-0.14342697267853247,-0.48182900048661537,1.3071593288497105,-0.7259104599277266,1.4380399974777385,0.255309170150584,-0.021142844948492293,0.6671420469276572,-0.5915469880276591,-0.8402469607675234,0.17753878759272398,0.11858418117435018,0.255309170150584,0.07897567452569614,-0.14342697267853247,0.3321505284860475,0.40809011351908236,0.4831539193642934,0.31302577253021713,2.4916088032578028,-0.10239964490688236,1.2740517609654562,-0.20547903817502652,1.0720060894912629,1.240785529211058,3.149741568733179,1.645661682349741,0.5388920140603658,0.6852623302074585,3.072090978975674,-0.2263016271137345,-0.3314804483105227,2.1911393985906495,2.4352981359162196,0.21654186145358403,0.612482250975132,0.11858418117435018,-0.021142844948492293,0.31302577253021713,0.29384424374464585,0.3512189297429039,1.566526139717696,0.9339209551785153,1.4703817232301912,0.2746055190128614,2.4352981359162196,-0.4384926181619229,-0.16404228682087726,1.8167337774526302,0.8638097235543348,0.6307523498834328 | 3,053 |
Inorganic molecular entity transmembrane transporter activity | 33 | 77 | 3.789345 | 0.000151 | P21796,Q99797,Q9C0H2,P12235,P05023,P45880,O95202,Q9Y487,O00400,Q9H813,O75964,Q9UBX3,Q4KMQ2,Q7KZN9,P20674,P04920,Q8IUH4,P16615,Q8NE86,Q9HC07,P36543,P20020,P13073,Q9HD20,Q13423,Q9Y6M7,Q96ES6,Q9UDW1,P24539,Q15526,Q9Y277,Q93050,P05141 | Functions | GO Molecular function | msigdb_gomf | 2,392,6,257,264,15,148,156,154,287,35,36,296,43,421,305,184,436,452,196,456,331,330,211,88,487,91,92,238,244,245,121,377 | 2023,154,625,977,35,148,691,305,264,377,1731,1055,2895,2353,1125,614,572,1507,257,330,436,331,421,1462,2264,2,238,2656,828,1222,456,2472,15,2776,927,1152,1010,830,1063,1470,733,648,588,531,757,88,1389,244,296,2859,2874,43,184,550,452,1704,1972,121,91,498,767,392,1244,6,769,287,793,196,211,814,36,92,2209,1546,245,156,487 | -0.37406084951540725,1.8167337774526302,0.4269371803541035,0.13829633186814977,3.2266342617272703,1.893169553532986,0.3702313895262678,1.0377463366595439,1.1905844892407613,0.8107434624970358,-0.24719447231895844,0.07897567452569614,-1.0758316877354026,-0.5254772864924734,0.039118345533642226,0.4457299111164649,0.5017859632503069,-0.16404228682087726,1.2073587193318431,0.9513357791761082,0.7033333538782307,0.9513357791761082,0.7213554512800274,-0.14342697267853247,-0.48182900048661537,4.914940523522634,1.3071593288497105,-0.7259104599277266,0.255309170150584,-0.021142844948492293,0.6671420469276572,-0.5915469880276591,4.096236762872413,-0.8402469607675234,0.17753878759272398,0.019095144049973707,0.11858418117435018,0.255309170150584,0.07897567452569614,-0.14342697267853247,0.3321505284860475,0.40809011351908236,0.4831539193642934,0.5573667616763491,0.31302577253021713,2.4916088032578028,-0.10239964490688236,1.2740517609654562,1.0720060894912629,-0.9804510545643588,-1.0041494608343033,3.149741568733179,1.645661682349741,0.5388920140603658,0.6852623302074585,-0.2263016271137345,-0.3314804483105227,2.1911393985906495,2.4352981359162196,0.612482250975132,0.31302577253021713,0.7929611203043013,-0.021142844948492293,4.433189930630274,0.31302577253021713,1.1060951140545585,0.29384424374464585,1.566526139717696,1.4703817232301912,0.2746055190128614,3.213870662525028,2.4352981359162196,-0.4384926181619229,-0.16404228682087726,1.2740517609654562,1.8167337774526302,0.6307523498834328 | 3,053 |
Sphingolipid metabolism | 16 | 27 | 3.745809 | 0.00018 | P16278,Q99519,Q06136,P06280,Q16739,Q13510,P51648,Q96G23,Q8TCT0,Q9NZJ7,P07602,P04062,P10619,P17900,O95470,P27544 | Processes and pathways | Reactome Pathways | msigdb_reactome | 65,132,102,231,136,40,138,11,169,275,113,56,185,186,61,159 | 1030,295,1451,625,1993,61,56,231,386,113,2598,185,65,186,1832,159,138,102,40,136,169,11,132,2419,998,275,2389 | 0.09881078799017154,1.0720060894912629,-0.14342697267853247,0.4269371803541035,-0.35273367187282356,2.780573201657302,2.861170882369116,1.3401101108679196,0.7929611203043013,2.2493125713395874,-0.6807859438462549,1.6299048673842986,2.739955797601633,1.6299048673842986,-0.28919332161258265,1.7859314470019894,1.9688079417064501,2.3500331786247033,3.162609148347032,1.998844642307609,1.7239281707505134,4.266395697843969,2.0585502205371826,-0.5474201594629304,0.13829633186814977,1.1569131412555997,-0.5254772864924734 | 3,053 |
Ion transmembrane transporter activity | 45 | 101 | 3.654659 | 0.000258 | P21796,Q9C0H2,P12235,P05023,P45880,O95202,P53985,Q9UJS0,Q9Y487,O00400,Q9H813,O75964,Q9UBX3,Q8TB61,Q4KMQ2,Q7KZN9,P20674,Q8NEW0,P04920,Q6P4A7,Q8IUH4,P16615,P12236,Q8NE86,Q9HC07,P36543,P20020,P13073,Q9HD20,Q9HC21,Q13423,Q9Y6M7,P30825,Q96ES6,Q9UDW1,Q9Y619,Q9H2D1,P41440,P24539,O43772,Q15526,Q9Y277,Q93050,Q70HW3,P05141 | Functions | GO Molecular function | msigdb_gomf | 2,6,257,264,15,148,403,151,156,154,287,35,36,39,296,43,421,49,305,309,184,436,188,452,196,456,331,330,211,339,88,487,214,91,92,365,109,362,238,241,244,245,121,251,377 | 2023,154,625,241,690,819,977,35,148,691,305,264,377,1731,1055,2895,2353,1125,614,572,1507,639,257,188,330,436,331,421,1462,2264,2,238,2656,214,828,1222,456,2472,362,15,2776,927,1152,1101,403,1010,830,1063,1470,733,648,588,531,757,88,1913,1389,244,1630,296,2859,2874,534,2686,309,251,43,184,550,452,49,39,1704,1972,121,91,890,498,767,1023,1137,1244,6,769,109,287,793,727,196,339,211,814,36,92,2209,151,1546,245,156,365,487 | -0.37406084951540725,1.8167337774526302,0.4269371803541035,1.2740517609654562,0.3702313895262678,0.255309170150584,0.13829633186814977,3.2266342617272703,1.893169553532986,0.3702313895262678,1.0377463366595439,1.1905844892407613,0.8107434624970358,-0.24719447231895844,0.07897567452569614,-1.0758316877354026,-0.5254772864924734,0.039118345533642226,0.4457299111164649,0.5017859632503069,-0.16404228682087726,0.40809011351908236,1.2073587193318431,1.6141131009311325,0.9513357791761082,0.7033333538782307,0.9513357791761082,0.7213554512800274,-0.14342697267853247,-0.48182900048661537,4.914940523522634,1.3071593288497105,-0.7259104599277266,1.4380399974777385,0.255309170150584,-0.021142844948492293,0.6671420469276572,-0.5915469880276591,0.8638097235543348,4.096236762872413,-0.8402469607675234,0.17753878759272398,0.019095144049973707,0.05907835699925959,0.7572541827182976,0.11858418117435018,0.255309170150584,0.07897567452569614,-0.14342697267853247,0.3321505284860475,0.40809011351908236,0.4831539193642934,0.5573667616763491,0.31302577253021713,2.4916088032578028,-0.31030054118727124,-0.10239964490688236,1.2740517609654562,-0.20547903817502652,1.0720060894912629,-0.9804510545643588,-1.0041494608343033,0.5573667616763491,-0.7486017803237077,1.0205517659257686,1.240785529211058,3.149741568733179,1.645661682349741,0.5388920140603658,0.6852623302074585,3.072090978975674,3.1882814967797093,-0.2263016271137345,-0.3314804483105227,2.1911393985906495,2.4352981359162196,0.21654186145358403,0.612482250975132,0.31302577253021713,0.11858418117435018,0.039118345533642226,-0.021142844948492293,4.433189930630274,0.31302577253021713,2.2926453330472487,1.1060951140545585,0.29384424374464585,0.3512189297429039,1.566526139717696,0.9339209551785153,1.4703817232301912,0.2746055190128614,3.213870662525028,2.4352981359162196,-0.4384926181619229,1.8626921049716938,-0.16404228682087726,1.2740517609654562,1.8167337774526302,0.8638097235543348,0.6307523498834328 | 3,053 |
Receptor | 20 | 54 | 3.64284 | 0.00027 | P24390,Q9NS69,O43731,Q15375,Q14108,Q99720,P36896,P20645,Q8WTV0,Q8IX05,O00264,Q14739,P15260,O15118,P35613,O15173,Q9Y5M8,Q9UNN8,P30825,Q99623 | Functions | Protein Atlas Molecular function | protein_atlas_molecular_function | 1,3,7,265,20,24,152,282,26,293,288,41,299,51,182,67,70,335,214,358 | 288,2215,513,51,67,7,446,1557,2501,1606,1940,1558,1055,2465,1672,2032,1942,371,559,1508,2074,299,824,282,1,214,182,152,1225,2634,618,2277,2442,1691,20,41,265,1630,836,293,26,2201,1805,1972,1355,358,24,3,444,335,2982,1719,70,2122 | 1.0890718099012444,-0.4601221695313692,0.5757898109834075,3.0329755799706857,2.7127576287713535,4.366865380443215,0.6852623302074585,-0.18472611797839597,-0.6137324247371202,-0.20547903817502652,-0.3314804483105227,-0.18472611797839597,0.07897567452569614,-0.5915469880276591,-0.2263016271137345,-0.37406084951540725,-0.3314804483105227,0.8284788048032764,0.5203652040028177,-0.16404228682087726,-0.3954626277985668,1.0548976876796043,0.255309170150584,1.123076264470747,5.242039873099177,1.4380399974777385,1.645661682349741,1.8474051204959177,-0.021142844948492293,-0.7033054530869399,0.4457299111164649,-0.48182900048661537,-0.5694431482641074,-0.2263016271137345,3.863819674290911,3.162609148347032,1.1905844892407613,-0.20547903817502652,0.255309170150584,1.0890718099012444,3.588162517641911,-0.4384926181619229,-0.2681581692824456,-0.3314804483105227,-0.08198652438815046,0.881405908837468,3.757058561044739,4.841737850614046,0.7033333538782307,0.9513357791761082,-1.4483758495299948,-0.2263016271137345,2.685462544005469,-0.3954626277985668 | 3,053 |
SLC superfamily of solute carriers | 26 | 47 | 3.596266 | 0.000323 | Q8IXU6,P12235,Q9NZJ7,O95202,P53985,Q6NUK1,Q9UJS0,O00400,Q9UBX3,Q8TB61,Q7L0J3,Q8NEW0,P04920,P12236,Q9HC07,Q9HC21,Q9BSK2,Q9Y6M7,P30825,Q9Y619,Q96QD8,P41440,Q9H2D1,O43772,Q70HW3,P05141 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 129,257,275,148,403,534,151,154,36,39,166,49,305,188,196,339,86,487,214,365,498,362,109,241,251,377 | 154,241,690,819,148,305,377,1125,639,257,188,875,214,362,1101,403,1010,648,531,1389,1630,2859,534,2686,251,166,129,49,39,1704,890,498,1023,86,1244,769,109,793,727,196,339,275,36,151,365,971,487 | 1.8167337774526302,1.2740517609654562,0.3702313895262678,0.255309170150584,1.893169553532986,1.0377463366595439,0.8107434624970358,0.039118345533642226,0.40809011351908236,1.2073587193318431,1.6141131009311325,0.21654186145358403,1.4380399974777385,0.8638097235543348,0.05907835699925959,0.7572541827182976,0.11858418117435018,0.40809011351908236,0.5573667616763491,-0.10239964490688236,-0.20547903817502652,-0.9804510545643588,0.5573667616763491,-0.7486017803237077,1.240785529211058,1.7394792650550464,2.10301243809186,3.072090978975674,3.1882814967797093,-0.2263016271137345,0.21654186145358403,0.612482250975132,0.11858418117435018,2.5056210267947026,-0.021142844948492293,0.31302577253021713,2.2926453330472487,0.29384424374464585,0.3512189297429039,1.566526139717696,0.9339209551785153,1.1569131412555997,3.213870662525028,1.8626921049716938,0.8638097235543348,0.15794771197129795,0.6307523498834328 | 3,053 |
Anion transport | 40 | 70 | 3.589431 | 0.000331 | P21796,Q9C0H2,P12235,Q00325,Q9NZJ7,P45880,O75915,P53985,Q6NUK1,Q9UJS0,Q02978,Q9H813,O00400,Q9UBX3,Q8TB61,Q4KMQ2,Q7L0J3,O60831,P04920,Q9UHG3,P12236,P0CG08,Q9H0H5,Q9HC21,Q9Y6M7,P30825,P08183,P14174,Q9Y619,Q96QD8,P41440,Q9H2D1,Q08722,P54105,P07602,Q9HD26,Q9Y277,Q13546,O43681,P05141 | Processes and pathways | GO Biological process | msigdb_gobp | 2,6,257,648,275,15,271,403,534,151,531,287,154,36,39,296,166,420,305,54,188,572,592,339,487,214,349,598,365,498,362,109,367,493,113,635,245,250,625,377 | 2023,154,625,690,1880,420,819,271,2772,305,377,1940,113,349,1125,572,639,257,188,598,3042,2,694,214,362,15,927,1152,1101,403,493,1010,2277,648,531,367,250,2145,1389,1630,296,2859,2874,534,2686,166,39,1704,890,498,767,1023,1244,6,592,109,287,793,727,339,635,814,275,36,54,151,245,2618,365,487 | -0.37406084951540725,1.8167337774526302,0.4269371803541035,0.3702313895262678,-0.31030054118727124,0.7213554512800274,0.255309170150584,1.1569131412555997,-0.8402469607675234,1.0377463366595439,0.8107434624970358,-0.3314804483105227,2.2493125713395874,0.8989563120030468,0.039118345533642226,0.5017859632503069,0.40809011351908236,1.2073587193318431,1.6141131009311325,0.464468695655408,-3.2311544845550535,4.914940523522634,0.3702313895262678,1.4380399974777385,0.8638097235543348,4.096236762872413,0.17753878759272398,0.019095144049973707,0.05907835699925959,0.7572541827182976,0.612482250975132,0.11858418117435018,-0.48182900048661537,0.40809011351908236,0.5573667616763491,0.846167456483267,1.240785529211058,-0.4169396623740783,-0.10239964490688236,-0.20547903817502652,1.0720060894912629,-0.9804510545643588,-1.0041494608343033,0.5573667616763491,-0.7486017803237077,1.7394792650550464,3.1882814967797093,-0.2263016271137345,0.21654186145358403,0.612482250975132,0.31302577253021713,0.11858418117435018,-0.021142844948492293,4.433189930630274,0.4831539193642934,2.2926453330472487,1.1060951140545585,0.29384424374464585,0.3512189297429039,0.9339209551785153,0.4269371803541035,0.2746055190128614,1.1569131412555997,3.213870662525028,2.980515400984891,1.8626921049716938,1.2740517609654562,-0.6807859438462549,0.8638097235543348,0.6307523498834328 | 3,053 |
Lysosomal lumen | 21 | 39 | 3.527415 | 0.00042 | Q99519,P06865,Q9NZJ7,Q14108,P50897,P54802,Q13510,Q9UMR5,Q8NHP8,P61916,P04062,P10619,P17900,P16278,Q9UM22,P07858,P06280,P38435,P11117,P07602,Q8IV08 | Localization | GO Cellular component | msigdb_gocc | 132,386,275,20,27,161,40,176,178,308,56,185,186,65,206,223,231,107,240,113,122 | 623,798,383,624,625,56,454,571,231,386,113,2598,223,981,596,573,185,240,1217,982,65,186,107,2898,27,161,308,40,20,122,2452,178,132,2107,1074,275,206,176,1718 | 0.4269371803541035,0.2746055190128614,0.7929611203043013,0.4269371803541035,0.4269371803541035,2.861170882369116,0.6671420469276572,0.5017859632503069,1.3401101108679196,0.7929611203043013,2.2493125713395874,-0.6807859438462549,1.3892463318502195,0.13829633186814977,0.464468695655408,0.5017859632503069,1.6299048673842986,1.2906252596776078,-0.021142844948492293,0.13829633186814977,2.739955797601633,1.6299048673842986,2.307033723210691,-1.0758316877354026,3.5515088405121995,1.7859314470019894,1.0205517659257686,3.162609148347032,3.863819674290911,2.1765244342071473,-0.5694431482641074,1.661383738534994,2.0585502205371826,-0.3954626277985668,0.07897567452569614,1.1569131412555997,1.502575541135129,1.6770712269532793,-0.2263016271137345 | 3,053 |
Inner mitochondrial membrane protein complex | 28 | 73 | 3.508515 | 0.000451 | Q9BUR5,O75489,O60830,O14949,O14925,Q99595,Q96CU9,O75964,Q13505,P03886,P20674,P03915,O43676,Q9NVH1,O95168,P12236,O75306,P22695,Q9P0J0,Q86Y39,P13073,Q5XKP0,P14406,Q9UDW1,Q99623,P24539,Q9Y512,O75438 | Localization | GO Cellular component | msigdb_gocc | 262,384,12,142,146,23,281,35,168,45,421,304,47,443,434,188,195,324,203,204,330,209,85,92,358,238,382,126 | 952,146,142,47,12,1177,195,2909,126,384,977,35,434,628,1604,978,595,691,45,304,1731,614,1458,1507,188,330,85,1298,1889,1831,421,782,324,238,2656,3014,2134,828,1059,1222,2775,2776,2183,783,830,900,1063,168,2413,650,886,986,549,209,739,204,1110,452,281,965,23,358,1494,262,2949,443,552,203,92,2907,1409,382,1053 | 0.15794771197129795,1.893169553532986,1.9537430602483536,3.072090978975674,4.210058257772574,-0.0009917498407377972,1.566526139717696,-1.099924828090018,2.1618805177312446,0.7929611203043013,0.13829633186814977,3.2266342617272703,0.7033333538782307,0.4269371803541035,-0.20547903817502652,0.13829633186814977,0.464468695655408,0.3702313895262678,3.0850861706306985,1.0377463366595439,-0.24719447231895844,0.4457299111164649,-0.14342697267853247,-0.16404228682087726,1.6141131009311325,0.9513357791761082,2.5056210267947026,-0.061639706843019025,-0.31030054118727124,-0.28919332161258265,0.7213554512800274,0.29384424374464585,0.9687059891173524,1.3071593288497105,-0.7259104599277266,-1.959204894557855,-0.4169396623740783,0.255309170150584,0.07897567452569614,-0.021142844948492293,-0.8402469607675234,-0.8402469607675234,-0.4384926181619229,0.29384424374464585,0.255309170150584,0.1970700191478118,0.07897567452569614,1.7239281707505134,-0.5474201594629304,0.40809011351908236,0.21654186145358403,0.13829633186814977,0.5388920140603658,1.4703817232301912,0.3321505284860475,1.502575541135129,0.05907835699925959,0.6852623302074585,1.1400155210794878,0.15794771197129795,3.8165416179463243,0.881405908837468,-0.14342697267853247,1.2073587193318431,-1.2219313118513195,0.7033333538782307,0.5388920140603658,1.5186175105719402,2.4352981359162196,-1.0758316877354026,-0.10239964490688236,0.8107434624970358,0.09881078799017154 | 3,053 |
Anion transmembrane transport | 21 | 43 | 3.497239 | 0.00047 | P21796,P12235,P45880,O75915,P53985,Q9UJS0,Q9UBX3,Q8TB61,Q4KMQ2,P04920,Q9UHG3,P12236,Q9HC21,P30825,P08183,Q9Y619,P41440,Q9H2D1,Q9Y277,Q13546,P05141 | Processes and pathways | GO Biological process | msigdb_gobp | 2,257,15,271,403,151,36,39,296,305,54,188,339,214,349,365,362,109,245,250,377 | 690,420,819,271,305,377,1940,349,1125,257,188,2,214,362,15,927,1152,1101,403,1010,2277,648,531,250,1630,296,2874,39,1704,890,1244,109,793,727,339,635,36,54,151,245,2618,365,487 | 0.3702313895262678,0.7213554512800274,0.255309170150584,1.1569131412555997,1.0377463366595439,0.8107434624970358,-0.3314804483105227,0.8989563120030468,0.039118345533642226,1.2073587193318431,1.6141131009311325,4.914940523522634,1.4380399974777385,0.8638097235543348,4.096236762872413,0.17753878759272398,0.019095144049973707,0.05907835699925959,0.7572541827182976,0.11858418117435018,-0.48182900048661537,0.40809011351908236,0.5573667616763491,1.240785529211058,-0.20547903817502652,1.0720060894912629,-1.0041494608343033,3.1882814967797093,-0.2263016271137345,0.21654186145358403,-0.021142844948492293,2.2926453330472487,0.29384424374464585,0.3512189297429039,0.9339209551785153,0.4269371803541035,3.213870662525028,2.980515400984891,1.8626921049716938,1.2740517609654562,-0.6807859438462549,0.8638097235543348,0.6307523498834328 | 3,053 |
Intrinsic component of organelle membrane | 57 | 116 | 3.423473 | 0.000618 | O15126,Q9BUR5,Q15070,P12235,O76024,P27824,O60830,Q9Y282,Q9UBM7,Q8TCT8,Q8IWA4,O14925,Q99442,Q99595,O60499,Q9NX63,P57088,Q8N4V1,Q86XL3,L0R6Q1,Q15629,Q8TB61,Q7L0J3,Q14739,Q13505,Q9BUN8,O15258,Q03518,Q8TCT9,Q96A33,O15118,Q9NVH1,Q6P4A7,Q9Y2R0,O95470,Q16134,Q8NE86,Q9UG56,O75844,Q5SNT2,P20020,Q5XKP0,Q9HC21,P42892,Q9P035,Q9Y4P3,O43505,O94901,Q9H490,Q9HCU5,Q9Y287,O95070,Q9NZ01,Q9Y512,Q9NQC3,P61020,Q9H3K2 | Localization | GO Cellular component | msigdb_gocc | 501,262,134,257,256,502,12,141,269,143,407,146,409,23,157,552,285,550,33,412,38,39,166,41,168,170,294,424,179,306,51,443,309,57,61,189,452,200,72,457,331,209,339,212,218,228,345,474,106,499,239,370,115,382,123,503,127 | 1030,412,999,146,51,501,294,729,1294,345,690,556,157,12,2909,72,627,256,1778,474,370,61,613,2653,692,597,257,331,1945,2702,502,2808,2775,212,1955,1098,674,285,959,503,733,648,424,1016,168,2370,41,2010,134,934,1105,38,189,886,549,457,209,2874,309,739,1588,166,2513,33,1043,407,1197,1700,550,1044,1166,452,1804,39,143,179,1045,944,2823,723,306,890,2584,409,23,1494,2419,915,170,262,967,127,106,727,339,499,2591,123,443,552,115,218,2851,269,200,2424,1404,1546,141,239,57,2019,228,1409,382,1364 | 0.09881078799017154,0.7393289521585672,0.11858418117435018,1.893169553532986,3.0329755799706857,0.5941615220565629,1.0720060894912629,0.3321505284860475,-0.061639706843019025,0.8989563120030468,0.3702313895262678,0.5203652040028177,1.8013490730391473,4.210058257772574,-1.099924828090018,2.658069675513038,0.4269371803541035,1.2073587193318431,-0.2681581692824456,0.6307523498834328,0.8284788048032764,2.780573201657302,0.4457299111164649,-0.7259104599277266,0.3702313895262678,0.464468695655408,1.2073587193318431,0.9513357791761082,-0.3314804483105227,-0.7713802427604488,0.5941615220565629,-0.8866095938314523,-0.8402469607675234,1.4542294549861097,-0.3314804483105227,0.05907835699925959,0.3891883162351104,1.1060951140545585,0.15794771197129795,0.5941615220565629,0.3321505284860475,0.40809011351908236,0.7213554512800274,0.11858418117435018,1.7239281707505134,-0.5254772864924734,3.162609148347032,-0.35273367187282356,2.0138167795559077,0.17753878759272398,0.05907835699925959,3.1882814967797093,1.6141131009311325,0.21654186145358403,0.5388920140603658,0.6671420469276572,1.4703817232301912,-1.0041494608343033,1.0205517659257686,0.3321505284860475,-0.18472611797839597,1.7394792650550464,-0.6137324247371202,3.3405919169416305,0.09881078799017154,0.7572541827182976,-0.0009917498407377972,-0.2263016271137345,0.5388920140603658,0.09881078799017154,0.019095144049973707,0.6852623302074585,-0.2681581692824456,3.1882814967797093,1.9537430602483536,1.661383738534994,0.09881078799017154,0.17753878759272398,-0.9099290428795153,0.3512189297429039,1.0377463366595439,0.21654186145358403,-0.6583511285219581,0.7572541827182976,3.8165416179463243,-0.14342697267853247,-0.5474201594629304,0.1970700191478118,1.7239281707505134,1.2073587193318431,0.15794771197129795,2.1325052522465455,2.3213944057139972,0.3512189297429039,0.9339209551785153,0.612482250975132,-0.6583511285219581,2.1765244342071473,0.7033333538782307,0.5388920140603658,2.2348120000348723,1.4380399974777385,-0.9568488266934512,1.1737693798534528,1.5346231303445235,-0.5474201594629304,-0.10239964490688236,-0.16404228682087726,1.9688079417064501,1.3071593288497105,2.861170882369116,-0.35273367187282356,1.372905949710868,-0.10239964490688236,0.8107434624970358,-0.08198652438815046 | 3,053 |
Sterol metabolic process | 18 | 38 | 3.411437 | 0.000646 | Q15800,P16435,Q06520,P35610,P34913,P37268,Q14739,Q9UBM7,O15118,Q9H2C2,P61916,Q14534,P04062,Q8WTV0,Q16850,Q15392,Q14849,Q9BQE5 | Processes and pathways | GO Biological process | msigdb_gobp | 95,323,4,258,325,197,41,269,51,192,308,183,56,26,60,29,30,63 | 51,2175,1826,2501,56,571,847,1297,1259,323,2533,325,258,197,2898,2267,326,1743,308,618,2680,2920,4,2574,183,41,30,885,1914,29,2280,95,60,26,63,192,269,2648 | 3.0329755799706857,-0.4384926181619229,-0.28919332161258265,-0.6137324247371202,2.861170882369116,0.5017859632503069,0.23595476382188807,-0.061639706843019025,-0.04135865661767714,0.9687059891173524,-0.6360002154493802,0.9687059891173524,1.2073587193318431,1.5505926056196673,-1.0758316877354026,-0.48182900048661537,0.9687059891173524,-0.24719447231895844,1.0205517659257686,0.4457299111164649,-0.7486017803237077,-1.1241192412166017,4.564311687934693,-0.6583511285219581,1.645661682349741,3.162609148347032,3.428112577652922,0.21654186145358403,-0.31030054118727124,3.4405377784263176,-0.48182900048661537,2.392786822066208,2.794064797575269,3.588162517641911,2.7670579060311247,1.6141131009311325,1.1737693798534528,-0.7033054530869399 | 3,053 |
Anion transmembrane transporter activity | 23 | 48 | 3.36851 | 0.000756 | P21796,Q9C0H2,P12235,P45880,P53985,Q6NUK1,Q9UJS0,Q9H813,O00400,Q9UBX3,Q8TB61,Q4KMQ2,P04920,P12236,Q9HC21,Q9Y6M7,P30825,Q9Y619,Q96QD8,P41440,Q9H2D1,Q9Y277,P05141 | Functions | GO Molecular function | msigdb_gomf | 2,6,257,15,403,534,151,287,154,36,39,296,305,188,339,487,214,365,498,362,109,245,377 | 2023,154,625,690,819,305,377,1125,572,639,257,188,2,214,362,15,927,1152,1101,403,1010,531,1389,1630,296,2859,2874,534,2686,39,1704,890,498,767,1023,1244,6,109,287,793,727,339,814,36,151,245,365,487 | -0.37406084951540725,1.8167337774526302,0.4269371803541035,0.3702313895262678,0.255309170150584,1.0377463366595439,0.8107434624970358,0.039118345533642226,0.5017859632503069,0.40809011351908236,1.2073587193318431,1.6141131009311325,4.914940523522634,1.4380399974777385,0.8638097235543348,4.096236762872413,0.17753878759272398,0.019095144049973707,0.05907835699925959,0.7572541827182976,0.11858418117435018,0.5573667616763491,-0.10239964490688236,-0.20547903817502652,1.0720060894912629,-0.9804510545643588,-1.0041494608343033,0.5573667616763491,-0.7486017803237077,3.1882814967797093,-0.2263016271137345,0.21654186145358403,0.612482250975132,0.31302577253021713,0.11858418117435018,-0.021142844948492293,4.433189930630274,2.2926453330472487,1.1060951140545585,0.29384424374464585,0.3512189297429039,0.9339209551785153,0.2746055190128614,3.213870662525028,1.8626921049716938,1.2740517609654562,0.8638097235543348,0.6307523498834328 | 3,053 |
Secondary alcohol metabolic process | 18 | 43 | 3.366789 | 0.00076 | Q15800,P16435,Q06520,P35610,P34913,P37268,Q14739,Q9UBM7,O15118,Q9H2C2,P61916,Q14534,P04062,Q8WTV0,Q16850,Q15392,Q14849,Q9BQE5 | Processes and pathways | GO Biological process | msigdb_gobp | 95,323,4,258,325,197,41,269,51,192,308,183,56,26,60,29,30,63 | 51,1002,663,2175,1826,2501,56,571,847,1297,1259,323,2533,325,258,197,2267,326,643,2855,1126,1743,308,618,2680,2920,4,2574,183,41,30,885,1914,29,2280,95,60,26,2783,63,192,269,2648 | 3.0329755799706857,0.11858418117435018,0.3891883162351104,-0.4384926181619229,-0.28919332161258265,-0.6137324247371202,2.861170882369116,0.5017859632503069,0.23595476382188807,-0.061639706843019025,-0.04135865661767714,0.9687059891173524,-0.6360002154493802,0.9687059891173524,1.2073587193318431,1.5505926056196673,-0.48182900048661537,0.9687059891173524,0.40809011351908236,-0.9804510545643588,0.039118345533642226,-0.24719447231895844,1.0205517659257686,0.4457299111164649,-0.7486017803237077,-1.1241192412166017,4.564311687934693,-0.6583511285219581,1.645661682349741,3.162609148347032,3.428112577652922,0.21654186145358403,-0.31030054118727124,3.4405377784263176,-0.48182900048661537,2.392786822066208,2.794064797575269,3.588162517641911,-0.8402469607675234,2.7670579060311247,1.6141131009311325,1.1737693798534528,-0.7033054530869399 | 3,053 |
Steroid binding | 12 | 20 | 3.364886 | 0.000766 | P21796,O00264,O15173,P35610,O95772,P05023,P38435,P45880,O15118,Q14108,P04062,Q14849 | Functions | GO Molecular function | msigdb_gomf | 2,288,67,258,68,264,107,15,51,20,56,30 | 288,51,67,2175,68,56,264,2353,2,1832,2078,258,107,15,308,20,30,1284,2059,705 | 1.0890718099012444,3.0329755799706857,2.7127576287713535,-0.4384926181619229,2.685462544005469,2.861170882369116,1.1905844892407613,-0.5254772864924734,4.914940523522634,-0.28919332161258265,-0.3954626277985668,1.2073587193318431,2.307033723210691,4.096236762872413,1.0205517659257686,3.863819674290911,3.428112577652922,-0.04135865661767714,-0.37406084951540725,0.3702313895262678 | 3,053 |
Ceramide metabolic process | 12 | 22 | 3.343528 | 0.000827 | Q99805,Q99519,P06280,Q16739,Q13510,Q8TCT0,Q96G23,P04062,Q8NCC3,P17900,O95470,P27544 | Processes and pathways | GO Biological process | msigdb_gobp | 128,132,231,136,40,169,11,56,89,186,61,159 | 295,1451,872,61,56,231,386,2598,186,1335,159,1032,2539,40,136,549,89,169,11,132,128,998 | 1.0720060894912629,-0.14342697267853247,0.21654186145358403,2.780573201657302,2.861170882369116,1.3401101108679196,0.7929611203043013,-0.6807859438462549,1.6299048673842986,-0.08198652438815046,1.7859314470019894,0.09881078799017154,-0.6360002154493802,3.162609148347032,1.998844642307609,0.5388920140603658,2.477570524290023,1.7239281707505134,4.266395697843969,2.0585502205371826,2.1177736122329143,0.13829633186814977 | 3,053 |
Mitochondrial transport | 21 | 75 | 3.308321 | 0.000939 | Q9NS69,Q15070,P12235,O60830,P45880,O14925,Q99595,Q9UJS0,Q14849,P23786,O75964,Q5JRX3,Q9UBX3,Q8N4H5,Q9P0J0,P52789,P24539,O43772,Q9Y512,O14737,P05141 | Processes and pathways | GO Biological process | msigdb_gobp | 3,134,257,12,15,146,23,151,30,284,35,164,36,64,203,226,238,241,382,252,377 | 252,146,872,527,241,12,2909,2128,977,35,1778,665,1086,1555,435,613,2352,377,1731,981,823,2829,257,1891,284,238,2656,2438,850,2265,1222,2267,15,2776,926,756,674,226,1687,830,1063,1520,2365,677,30,134,1105,2095,986,549,164,534,2608,1197,1700,64,1804,1281,994,1397,23,392,811,2949,3,203,1247,36,747,151,796,2907,2121,382,2255 | 1.2240923176202834,1.893169553532986,0.21654186145358403,0.5573667616763491,1.2740517609654562,4.210058257772574,-1.099924828090018,-0.4169396623740783,0.13829633186814977,3.2266342617272703,-0.2681581692824456,0.3891883162351104,0.05907835699925959,-0.18472611797839597,0.7033333538782307,0.4457299111164649,-0.5254772864924734,0.8107434624970358,-0.24719447231895844,0.13829633186814977,0.255309170150584,-0.9333418075172426,1.2073587193318431,-0.31030054118727124,1.1060951140545585,1.3071593288497105,-0.7259104599277266,-0.5694431482641074,0.23595476382188807,-0.48182900048661537,-0.021142844948492293,-0.48182900048661537,4.096236762872413,-0.8402469607675234,0.17753878759272398,0.31302577253021713,0.3891883162351104,1.372905949710868,-0.2263016271137345,0.255309170150584,0.07897567452569614,-0.16404228682087726,-0.5254772864924734,0.3891883162351104,3.428112577652922,2.0138167795559077,0.05907835699925959,-0.3954626277985668,0.13829633186814977,0.5388920140603658,1.7704807226942911,0.5573667616763491,-0.6807859438462549,-0.0009917498407377972,-0.2263016271137345,2.7535188063677927,-0.2681581692824456,-0.04135865661767714,0.13829633186814977,-0.10239964490688236,3.8165416179463243,0.7929611203043013,0.2746055190128614,-1.2219313118513195,4.841737850614046,1.5186175105719402,-0.021142844948492293,3.213870662525028,0.3321505284860475,1.8626921049716938,0.29384424374464585,-1.0758316877354026,-0.3954626277985668,0.8107434624970358,-0.4601221695313692 | 3,053 |
Secondary active transmembrane transporter activity | 13 | 25 | 3.232955 | 0.001225 | Q8NE86,Q9UBX3,P12235,Q96QD8,P41440,P04920,O95202,P53985,Q9Y6M7,Q96ES6,O00400,P05141,P12236 | Functions | GO Molecular function | msigdb_gomf | 452,36,257,498,362,305,148,403,487,91,154,377,188 | 154,148,305,377,1125,257,188,362,927,1152,1101,403,1010,648,531,1389,1630,452,1704,91,498,1244,793,36,487 | 1.8167337774526302,1.893169553532986,1.0377463366595439,0.8107434624970358,0.039118345533642226,1.2073587193318431,1.6141131009311325,0.8638097235543348,0.17753878759272398,0.019095144049973707,0.05907835699925959,0.7572541827182976,0.11858418117435018,0.40809011351908236,0.5573667616763491,-0.10239964490688236,-0.20547903817502652,0.6852623302074585,-0.2263016271137345,2.4352981359162196,0.612482250975132,-0.021142844948492293,0.29384424374464585,3.213870662525028,0.6307523498834328 | 3,053 |
Mitochondrial transmembrane transport | 18 | 47 | 3.224842 | 0.00126 | P12236,P21796,O75964,P12235,Q9Y619,O60830,Q9H2D1,P24539,O43772,O95202,O14925,P05141,Q9BSK2,Q99595,Q9UJS0,O95831,Q6P4A7,P23786 | Processes and pathways | GO Biological process | msigdb_gobp | 188,2,35,257,365,12,109,238,241,148,146,377,86,23,151,435,309,284 | 146,527,241,12,1369,2128,819,977,35,1778,148,435,613,377,1731,2829,257,188,2,284,238,2656,1222,2776,1101,830,1063,648,1105,2194,986,309,1110,452,1592,890,23,1494,86,109,793,727,2949,151,796,1409,365 | 1.893169553532986,0.5573667616763491,1.2740517609654562,4.210058257772574,-0.10239964490688236,-0.4169396623740783,0.255309170150584,0.13829633186814977,3.2266342617272703,-0.2681581692824456,1.893169553532986,0.7033333538782307,0.4457299111164649,0.8107434624970358,-0.24719447231895844,-0.9333418075172426,1.2073587193318431,1.6141131009311325,4.914940523522634,1.1060951140545585,1.3071593288497105,-0.7259104599277266,-0.021142844948492293,-0.8402469607675234,0.05907835699925959,0.255309170150584,0.07897567452569614,0.40809011351908236,0.05907835699925959,-0.4384926181619229,0.13829633186814977,1.0205517659257686,0.05907835699925959,0.6852623302074585,-0.18472611797839597,0.21654186145358403,3.8165416179463243,-0.14342697267853247,2.5056210267947026,2.2926453330472487,0.29384424374464585,0.3512189297429039,-1.2219313118513195,1.8626921049716938,0.29384424374464585,-0.10239964490688236,0.8638097235543348 | 3,053 |
Retinopathy | 12 | 29 | 3.205498 | 0.001348 | O75306,Q99519,Q8NHS3,P49327,Q9NZ08,P51648,Q92889,O95202,Q15526,O96028,Q15555,P07437 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 195,132,37,229,137,138,202,148,244,181,219,348 | 556,1775,195,628,148,2069,181,2653,348,1003,825,1090,925,1951,229,138,1185,1193,244,219,1270,37,202,1397,132,1442,2494,137,397 | 0.5203652040028177,-0.2681581692824456,1.566526139717696,0.4269371803541035,1.893169553532986,-0.3954626277985668,1.645661682349741,-0.7259104599277266,0.8989563120030468,0.11858418117435018,0.255309170150584,0.05907835699925959,0.17753878759272398,-0.3314804483105227,1.3565272843725606,1.9688079417064501,-0.0009917498407377972,-0.0009917498407377972,1.2740517609654562,1.405548653662622,-0.04135865661767714,3.2010864353849686,1.5186175105719402,-0.10239964490688236,2.0585502205371826,-0.12287961106727112,-0.5915469880276591,1.998844642307609,0.7929611203043013 | 3,053 |
Ion transport | 21 | 52 | 3.204565 | 0.001353 | P21796,Q9C0H2,P05023,P45880,O95202,Q9Y487,Q9H813,O75964,Q4KMQ2,Q8NEW0,P04920,P16615,Q8NE86,Q15904,P36543,Q8NE01,P20020,Q9Y6M7,P24539,Q9Y277,Q93050 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 2,6,264,15,148,156,287,35,296,49,305,436,452,318,456,458,331,487,238,245,121 | 2023,977,35,148,613,305,264,1731,572,436,331,1462,2264,2,238,2656,1222,456,2472,15,2776,927,1152,577,1010,830,1063,1470,757,1913,1389,318,296,2859,2874,458,452,49,1704,121,498,767,1494,1137,6,592,287,2209,1546,245,156,487 | -0.37406084951540725,0.13829633186814977,3.2266342617272703,1.893169553532986,0.4457299111164649,1.0377463366595439,1.1905844892407613,-0.24719447231895844,0.5017859632503069,0.7033333538782307,0.9513357791761082,-0.14342697267853247,-0.48182900048661537,4.914940523522634,1.3071593288497105,-0.7259104599277266,-0.021142844948492293,0.6671420469276572,-0.5915469880276591,4.096236762872413,-0.8402469607675234,0.17753878759272398,0.019095144049973707,0.5017859632503069,0.11858418117435018,0.255309170150584,0.07897567452569614,-0.14342697267853247,0.31302577253021713,-0.31030054118727124,-0.10239964490688236,0.9860318695770233,1.0720060894912629,-0.9804510545643588,-1.0041494608343033,0.6671420469276572,0.6852623302074585,3.072090978975674,-0.2263016271137345,2.1911393985906495,0.612482250975132,0.31302577253021713,-0.14342697267853247,0.039118345533642226,4.433189930630274,0.4831539193642934,1.1060951140545585,-0.4384926181619229,-0.16404228682087726,1.2740517609654562,1.8167337774526302,0.6307523498834328 | 3,053 |
Monovalent inorganic cation homeostasis | 17 | 31 | 3.196095 | 0.001393 | Q15904,Q9P0T7,Q9Y5X3,Q8N511,Q9HC07,O75787,P54709,P05023,Q14964,P50897,P04920,Q92544,Q93050,Q9Y6M7,Q96PU5,Q9Y487,O75503 | Processes and pathways | GO Biological process | msigdb_gobp | 318,396,131,58,196,446,577,264,388,27,305,538,121,487,286,156,158 | 158,446,1455,305,264,1731,572,2079,1736,27,1098,927,577,1010,1470,388,318,58,538,1704,121,861,286,1244,196,396,708,2209,156,131,487 | 1.8013490730391473,0.6852623302074585,-0.14342697267853247,1.0377463366595439,1.1905844892407613,-0.24719447231895844,0.5017859632503069,-0.3954626277985668,-0.24719447231895844,3.5515088405121995,0.05907835699925959,0.17753878759272398,0.5017859632503069,0.11858418117435018,-0.14342697267853247,0.7929611203043013,0.9860318695770233,2.834398419466517,0.5573667616763491,-0.2263016271137345,2.1911393985906495,0.23595476382188807,1.1060951140545585,-0.021142844948492293,1.566526139717696,0.7929611203043013,0.3702313895262678,-0.4384926181619229,1.8167337774526302,2.0882215813866165,0.6307523498834328 | 3,053 |
Active ion transmembrane transporter activity | 20 | 42 | 3.167426 | 0.001538 | P12235,P05023,O95202,O00400,Q7KZN9,P20674,P04920,P16615,P12236,P36543,P20020,P13073,Q9HD20,Q9Y6M7,Q96ES6,Q9UDW1,Q96QD8,P41440,Q15526,P05141 | Functions | GO Molecular function | msigdb_gomf | 257,264,148,154,43,421,305,436,188,456,331,330,211,487,91,92,498,362,244,377 | 154,148,691,305,264,377,1731,1125,614,1507,257,188,330,436,331,421,1462,2264,828,456,2472,362,927,1152,1101,1010,1470,648,531,757,1389,244,43,1704,91,498,1244,793,211,92,2209,487 | 1.8167337774526302,1.893169553532986,0.3702313895262678,1.0377463366595439,1.1905844892407613,0.8107434624970358,-0.24719447231895844,0.039118345533642226,0.4457299111164649,-0.16404228682087726,1.2073587193318431,1.6141131009311325,0.9513357791761082,0.7033333538782307,0.9513357791761082,0.7213554512800274,-0.14342697267853247,-0.48182900048661537,0.255309170150584,0.6671420469276572,-0.5915469880276591,0.8638097235543348,0.17753878759272398,0.019095144049973707,0.05907835699925959,0.11858418117435018,-0.14342697267853247,0.40809011351908236,0.5573667616763491,0.31302577253021713,-0.10239964490688236,1.2740517609654562,3.149741568733179,-0.2263016271137345,2.4352981359162196,0.612482250975132,-0.021142844948492293,0.29384424374464585,1.4703817232301912,2.4352981359162196,-0.4384926181619229,0.6307523498834328 | 3,053 |
Organic anion transmembrane transporter activity | 16 | 28 | 3.157258 | 0.001593 | Q6NUK1,Q9UBX3,P12235,Q8TB61,Q9Y619,Q96QD8,P41440,Q9H2D1,Q9HC21,P53985,Q9UJS0,Q9Y6M7,P30825,O00400,P05141,P12236 | Functions | GO Molecular function | msigdb_gomf | 534,36,257,39,365,498,362,109,339,403,151,487,214,154,377,188 | 154,690,819,377,1125,639,257,188,214,362,1101,403,531,1630,534,2686,39,890,498,1023,109,793,727,339,36,151,365,487 | 1.8167337774526302,0.3702313895262678,0.255309170150584,0.8107434624970358,0.039118345533642226,0.40809011351908236,1.2073587193318431,1.6141131009311325,1.4380399974777385,0.8638097235543348,0.05907835699925959,0.7572541827182976,0.5573667616763491,-0.20547903817502652,0.5573667616763491,-0.7486017803237077,3.1882814967797093,0.21654186145358403,0.612482250975132,0.11858418117435018,2.2926453330472487,0.29384424374464585,0.3512189297429039,0.9339209551785153,3.213870662525028,1.8626921049716938,0.8638097235543348,0.6307523498834328 | 3,053 |
Vacuolar lumen | 27 | 72 | 3.149794 | 0.001634 | Q99519,P06865,O00754,Q9NZJ7,O75629,Q14108,P50897,P54802,Q13510,Q9UMR5,Q8NHP8,P61916,P04062,P10619,P17900,P16278,P04066,Q9UM22,P68371,Q9BTY2,P07437,P07858,P06280,P38435,P11117,P07602,Q8IV08 | Localization | GO Cellular component | msigdb_gocc | 132,386,383,275,147,20,27,161,40,176,178,308,56,185,186,65,454,206,332,462,348,223,231,107,240,113,122 | 623,1365,798,383,624,625,147,1826,56,454,571,231,386,2895,348,113,2598,223,981,596,573,185,240,1217,1562,982,65,186,2882,1736,1220,107,2898,1008,27,2231,1743,1127,2320,161,2569,1422,308,332,2004,2857,1381,2539,2369,40,20,1478,122,2452,178,764,914,1973,132,657,2107,3002,462,1074,2713,481,2801,275,206,176,2253,1718 | 0.4269371803541035,-0.10239964490688236,0.2746055190128614,0.7929611203043013,0.4269371803541035,0.4269371803541035,1.893169553532986,-0.28919332161258265,2.861170882369116,0.6671420469276572,0.5017859632503069,1.3401101108679196,0.7929611203043013,-1.0758316877354026,0.8989563120030468,2.2493125713395874,-0.6807859438462549,1.3892463318502195,0.13829633186814977,0.464468695655408,0.5017859632503069,1.6299048673842986,1.2906252596776078,-0.021142844948492293,-0.18472611797839597,0.13829633186814977,2.739955797601633,1.6299048673842986,-1.0279450311062537,-0.24719447231895844,-0.021142844948492293,2.307033723210691,-1.0758316877354026,0.11858418117435018,3.5515088405121995,-0.4601221695313692,-0.24719447231895844,0.039118345533642226,-0.5036138048570713,1.7859314470019894,-0.6583511285219581,-0.12287961106727112,1.0205517659257686,0.9513357791761082,-0.35273367187282356,-0.9804510545643588,-0.10239964490688236,-0.6360002154493802,-0.5254772864924734,3.162609148347032,3.863819674290911,-0.14342697267853247,2.1765244342071473,-0.5694431482641074,1.661383738534994,0.31302577253021713,0.1970700191478118,-0.3314804483105227,2.0585502205371826,0.40809011351908236,-0.3954626277985668,-1.6843993378217588,0.6671420469276572,0.07897567452569614,-0.7713802427604488,0.6307523498834328,-0.8633825363003653,1.1569131412555997,1.502575541135129,1.6770712269532793,-0.4601221695313692,-0.2263016271137345 | 3,053 |
Membrane lipid biosynthetic process | 10 | 25 | 3.140639 | 0.001686 | Q99805,Q06136,Q13510,Q16739,Q9H490,Q96G23,Q9P035,P04062,O95470,P27544 | Processes and pathways | GO Biological process | msigdb_gobp | 128,102,40,136,106,11,218,56,61,159 | 295,1451,729,1775,61,56,1335,1832,159,1895,2539,102,40,136,549,451,944,2823,11,2584,128,106,998,218,2389 | 1.0720060894912629,-0.14342697267853247,0.3321505284860475,-0.2681581692824456,2.780573201657302,2.861170882369116,-0.08198652438815046,-0.28919332161258265,1.7859314470019894,-0.31030054118727124,-0.6360002154493802,2.3500331786247033,3.162609148347032,1.998844642307609,0.5388920140603658,0.6852623302074585,0.17753878759272398,-0.9099290428795153,4.266395697843969,-0.6583511285219581,2.1177736122329143,2.3213944057139972,0.13829633186814977,1.4380399974777385,-0.5254772864924734 | 3,053 |
Slc mediated transmembrane transport | 13 | 26 | 3.137906 | 0.001702 | Q9UBX3,P12235,Q8TB61,Q8NEW0,P04920,P53985,P35613,Q9Y6M7,P30825,Q70HW3,O00400,P05141,P12236 | Processes and pathways | Reactome Pathways | msigdb_reactome | 36,257,39,49,305,403,182,487,214,251,154,377,188 | 154,305,377,1125,639,257,188,875,1999,214,182,574,403,1010,1389,1630,2686,251,49,39,1704,498,1023,793,36,487 | 1.8167337774526302,1.0377463366595439,0.8107434624970358,0.039118345533642226,0.40809011351908236,1.2073587193318431,1.6141131009311325,0.21654186145358403,-0.35273367187282356,1.4380399974777385,1.645661682349741,0.5017859632503069,0.7572541827182976,0.11858418117435018,-0.10239964490688236,-0.20547903817502652,-0.7486017803237077,1.240785529211058,3.072090978975674,3.1882814967797093,-0.2263016271137345,0.612482250975132,0.11858418117435018,0.29384424374464585,3.213870662525028,0.6307523498834328 | 3,053 |
Cellular monovalent inorganic cation homeostasis | 16 | 28 | 3.131288 | 0.00174 | Q15904,Q9P0T7,Q8N511,Q9HC07,O75787,P54709,P05023,Q14964,P50897,P04920,Q92544,Q93050,Q9Y6M7,Q96PU5,Q9Y487,O75503 | Processes and pathways | GO Biological process | msigdb_gobp | 318,396,58,196,446,577,264,388,27,305,538,121,487,286,156,158 | 158,446,305,264,1731,572,2079,1736,27,1098,927,577,1010,1470,388,318,58,538,1704,121,861,286,196,396,708,2209,156,487 | 1.8013490730391473,0.6852623302074585,1.0377463366595439,1.1905844892407613,-0.24719447231895844,0.5017859632503069,-0.3954626277985668,-0.24719447231895844,3.5515088405121995,0.05907835699925959,0.17753878759272398,0.5017859632503069,0.11858418117435018,-0.14342697267853247,0.7929611203043013,0.9860318695770233,2.834398419466517,0.5573667616763491,-0.2263016271137345,2.1911393985906495,0.23595476382188807,1.1060951140545585,1.566526139717696,0.7929611203043013,0.3702313895262678,-0.4384926181619229,1.8167337774526302,0.6307523498834328 | 3,053 |
transporter | 25 | 58 | 3.130066 | 0.001748 | Q99805,Q9HAV4,Q15070,O60830,Q8N1F7,Q92544,Q8NFH4,P53985,Q99595,P48739,O43615,Q15012,Q00169,O15397,Q92973,O95373,Q567V2,P52292,Q9HD45,P39210,Q9Y619,P41440,Q9H2D1,P54105,O43772 | Functions | Panther Protein class | panther_protein_class | 128,523,134,12,399,538,537,403,23,529,527,32,415,289,167,298,48,94,96,105,365,362,109,493,241 | 951,1449,2934,1214,1663,289,527,625,241,626,12,2027,298,1949,1261,105,362,529,2085,94,645,2087,1101,403,493,563,2571,733,415,903,2372,32,134,48,2859,809,399,537,1072,763,538,167,1046,790,1205,23,128,1023,3007,725,109,523,96,2164,2615,796,1720,365 | 0.15794771197129795,-0.14342697267853247,-1.1728161868952576,-0.021142844948492293,-0.2263016271137345,1.0890718099012444,0.5573667616763491,0.4269371803541035,1.2740517609654562,0.4269371803541035,4.210058257772574,-0.37406084951540725,1.0548976876796043,-0.3314804483105227,-0.04135865661767714,2.3213944057139972,0.8638097235543348,0.5573667616763491,-0.3954626277985668,2.4069840158349467,0.40809011351908236,-0.3954626277985668,0.05907835699925959,0.7572541827182976,0.612482250975132,0.5203652040028177,-0.6583511285219581,0.3321505284860475,0.7393289521585672,0.1970700191478118,-0.5254772864924734,3.390720955781931,2.0138167795559077,3.072090978975674,-0.9804510545643588,0.2746055190128614,0.7751314656744809,0.5573667616763491,0.07897567452569614,0.31302577253021713,0.5573667616763491,1.7394792650550464,0.09881078799017154,0.29384424374464585,-0.0009917498407377972,3.8165416179463243,2.1177736122329143,0.11858418117435018,-1.7926493260910925,0.3512189297429039,2.2926453330472487,0.5757898109834075,2.392786822066208,-0.4169396623740783,-0.6807859438462549,0.29384424374464585,-0.2263016271137345,0.8638097235543348 | 3,053 |
Corneal opacity | 27 | 56 | 3.090404 | 0.001999 | Q9NVI7,Q99519,P51648,Q9UBM7,O00754,O95202,Q16625,Q6NUK1,P53701,P40855,Q13510,O96028,P04062,P10619,P16278,P34913,P04066,P04114,Q92889,O75844,Q12948,O75569,Q9Y4P3,O43505,Q06136,P06280,O75381 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 395,132,138,269,383,148,406,534,160,543,40,181,56,185,65,325,454,571,202,72,602,347,228,345,102,231,488 | 383,1987,2928,1665,345,2304,1329,2431,488,347,72,2129,148,181,2501,2771,56,454,571,231,596,1996,185,65,825,1090,325,2601,543,2359,138,1185,160,2141,2537,1574,1130,102,1383,602,1193,40,1428,1584,1585,406,534,1631,202,132,1171,395,2957,269,1769,228 | 0.7929611203043013,-0.35273367187282356,-1.1484159978357622,-0.2263016271137345,0.8989563120030468,-0.5036138048570713,-0.08198652438815046,-0.5694431482641074,0.612482250975132,0.8989563120030468,2.658069675513038,-0.4169396623740783,1.893169553532986,1.645661682349741,-0.6137324247371202,-0.8402469607675234,2.861170882369116,0.6671420469276572,0.5017859632503069,1.3401101108679196,0.464468695655408,-0.35273367187282356,1.6299048673842986,2.739955797601633,0.255309170150584,0.05907835699925959,0.9687059891173524,-0.6807859438462549,0.5388920140603658,-0.5254772864924734,1.9688079417064501,-0.0009917498407377972,1.7859314470019894,-0.4169396623740783,-0.6360002154493802,-0.18472611797839597,0.039118345533642226,2.3500331786247033,-0.10239964490688236,0.464468695655408,-0.0009917498407377972,3.162609148347032,-0.12287961106727112,-0.18472611797839597,-0.18472611797839597,0.7572541827182976,0.5573667616763491,-0.20547903817502652,1.5186175105719402,2.0585502205371826,0.019095144049973707,0.7929611203043013,-1.2714737088540449,1.1737693798534528,-0.24719447231895844,1.372905949710868 | 3,053 |
Parkinsons disease | 19 | 53 | 3.090211 | 0.002 | P21796,P12235,O75489,O14949,P45880,P03886,P20674,P03915,O43676,P12236,O75306,P22695,P13073,P14406,Q9UDW1,P24539,Q9Y277,P05141,O75438 | Processes and pathways | KEGG Pathways | msigdb_kegg | 2,257,384,142,15,45,421,304,47,188,195,324,330,85,92,238,245,377,126 | 952,142,872,47,1177,195,126,384,977,434,628,1604,978,595,691,45,304,377,1731,614,1458,1507,257,188,330,85,1298,1889,1831,421,2,782,1782,324,238,2656,3014,2134,828,1222,1466,15,2776,2183,783,1520,2323,2413,650,2847,92,245,1053 | 0.15794771197129795,1.9537430602483536,0.21654186145358403,3.072090978975674,-0.0009917498407377972,1.566526139717696,2.1618805177312446,0.7929611203043013,0.13829633186814977,0.7033333538782307,0.4269371803541035,-0.20547903817502652,0.13829633186814977,0.464468695655408,0.3702313895262678,3.0850861706306985,1.0377463366595439,0.8107434624970358,-0.24719447231895844,0.4457299111164649,-0.14342697267853247,-0.16404228682087726,1.2073587193318431,1.6141131009311325,0.9513357791761082,2.5056210267947026,-0.061639706843019025,-0.31030054118727124,-0.28919332161258265,0.7213554512800274,4.914940523522634,0.29384424374464585,-0.2681581692824456,0.9687059891173524,1.3071593288497105,-0.7259104599277266,-1.959204894557855,-0.4169396623740783,0.255309170150584,-0.021142844948492293,-0.14342697267853247,4.096236762872413,-0.8402469607675234,-0.4384926181619229,0.29384424374464585,-0.16404228682087726,-0.5036138048570713,-0.5474201594629304,0.40809011351908236,-0.9568488266934512,2.4352981359162196,1.2740517609654562,0.09881078799017154 | 3,053 |
Respirasome | 19 | 43 | 3.087194 | 0.002021 | O75489,Q6DKK2,O14949,Q96CU9,Q7KZN9,P03886,P20674,P03915,O43676,O75306,P22695,Q9P0J0,Q86Y39,P13073,P14406,Q13423,Q9UDW1,Q15526,O75438 | Localization | GO Cellular component | msigdb_gocc | 384,140,142,281,43,45,421,304,47,195,324,203,204,330,85,88,92,244,126 | 952,142,47,1177,195,126,384,434,628,1604,978,595,691,45,304,614,1458,1507,330,85,1298,1889,1831,421,782,324,3014,2134,828,2183,783,88,244,2413,650,140,43,204,281,203,92,2907,1053 | 0.15794771197129795,1.9537430602483536,3.072090978975674,-0.0009917498407377972,1.566526139717696,2.1618805177312446,0.7929611203043013,0.7033333538782307,0.4269371803541035,-0.20547903817502652,0.13829633186814977,0.464468695655408,0.3702313895262678,3.0850861706306985,1.0377463366595439,0.4457299111164649,-0.14342697267853247,-0.16404228682087726,0.9513357791761082,2.5056210267947026,-0.061639706843019025,-0.31030054118727124,-0.28919332161258265,0.7213554512800274,0.29384424374464585,0.9687059891173524,-1.959204894557855,-0.4169396623740783,0.255309170150584,-0.4384926181619229,0.29384424374464585,2.4916088032578028,1.2740517609654562,-0.5474201594629304,0.40809011351908236,1.9688079417064501,3.149741568733179,1.502575541135129,1.1400155210794878,1.5186175105719402,2.4352981359162196,-1.0758316877354026,0.09881078799017154 | 3,053 |
Transporter activity | 75 | 175 | 3.081178 | 0.002062 | Q8IXU6,P21796,Q9NS69,Q99797,Q9C0H2,P12235,P05023,O60830,O75489,P45880,O95202,O14925,P53985,Q99595,Q9UJS0,Q8WTV0,Q9Y487,O00400,Q9H813,Q14849,Q00169,O75964,Q9UBX3,Q8NHS3,L0R6Q1,Q8TB61,Q7L0J3,Q4KMQ2,Q7KZN9,P03886,P20674,Q03518,P03915,Q8NEW0,O43676,O15118,P04920,P61916,Q6P4A7,P04062,Q8IUH4,P17900,P16615,O95168,Q9H2C2,P12236,Q8NE86,O15173,O75306,Q9HC07,P36543,Q9P0J0,P20020,P13073,Q9HD20,Q9HC21,Q9BSK2,Q13423,P30825,Q96ES6,Q9UDW1,P08183,P39210,Q9Y619,P38435,Q9H2D1,P41440,P24539,O43772,Q15526,Q9Y277,Q93050,Q70HW3,P05141,O75438 | Functions | GO Molecular function | msigdb_gomf | 129,2,3,392,6,257,264,12,384,15,148,146,403,23,151,26,156,154,287,30,415,35,36,37,412,39,166,296,43,45,421,424,304,49,47,51,305,308,309,56,184,186,436,434,192,188,452,67,195,196,456,203,331,330,211,339,86,88,214,91,92,349,105,365,107,109,362,238,241,244,245,121,251,377,126 | 412,2023,154,952,1250,146,51,67,47,625,241,690,12,1369,1177,195,126,384,819,977,35,1778,434,628,1604,148,978,595,613,691,45,304,56,571,305,264,377,1731,1055,2895,2465,2353,349,1125,614,572,1507,639,257,188,330,875,436,186,1831,331,421,1462,2264,2,1832,238,2656,694,3014,214,828,1222,456,107,2472,105,362,15,2776,529,544,2183,927,1152,783,545,2087,1101,403,1010,830,1063,1470,733,308,2277,415,648,588,2857,531,424,757,2365,2366,88,2948,1913,30,1389,1105,244,1630,2413,650,296,2859,2874,534,2686,309,251,43,166,184,129,550,1313,458,452,49,37,39,26,1704,1972,121,91,890,498,767,1284,1205,23,392,1023,2585,86,1137,2059,1244,705,6,769,192,109,287,793,727,196,339,211,3,541,814,203,36,92,867,2209,151,1546,1289,245,156,2255,365,487,1053 | 0.7393289521585672,-0.37406084951540725,1.8167337774526302,0.15794771197129795,-0.04135865661767714,1.893169553532986,3.0329755799706857,2.7127576287713535,3.072090978975674,0.4269371803541035,1.2740517609654562,0.3702313895262678,4.210058257772574,-0.10239964490688236,-0.0009917498407377972,1.566526139717696,2.1618805177312446,0.7929611203043013,0.255309170150584,0.13829633186814977,3.2266342617272703,-0.2681581692824456,0.7033333538782307,0.4269371803541035,-0.20547903817502652,1.893169553532986,0.13829633186814977,0.464468695655408,0.4457299111164649,0.3702313895262678,3.0850861706306985,1.0377463366595439,2.861170882369116,0.5017859632503069,1.0377463366595439,1.1905844892407613,0.8107434624970358,-0.24719447231895844,0.07897567452569614,-1.0758316877354026,-0.5915469880276591,-0.5254772864924734,0.8989563120030468,0.039118345533642226,0.4457299111164649,0.5017859632503069,-0.16404228682087726,0.40809011351908236,1.2073587193318431,1.6141131009311325,0.9513357791761082,0.21654186145358403,0.7033333538782307,1.6299048673842986,-0.28919332161258265,0.9513357791761082,0.7213554512800274,-0.14342697267853247,-0.48182900048661537,4.914940523522634,-0.28919332161258265,1.3071593288497105,-0.7259104599277266,0.3702313895262678,-1.959204894557855,1.4380399974777385,0.255309170150584,-0.021142844948492293,0.6671420469276572,2.307033723210691,-0.5915469880276591,2.3213944057139972,0.8638097235543348,4.096236762872413,-0.8402469607675234,0.5573667616763491,0.5388920140603658,-0.4384926181619229,0.17753878759272398,0.019095144049973707,0.29384424374464585,0.5388920140603658,-0.3954626277985668,0.05907835699925959,0.7572541827182976,0.11858418117435018,0.255309170150584,0.07897567452569614,-0.14342697267853247,0.3321505284860475,1.0205517659257686,-0.48182900048661537,0.7393289521585672,0.40809011351908236,0.4831539193642934,-0.9804510545643588,0.5573667616763491,0.7213554512800274,0.31302577253021713,-0.5254772864924734,-0.5254772864924734,2.4916088032578028,-1.2219313118513195,-0.31030054118727124,3.428112577652922,-0.10239964490688236,0.05907835699925959,1.2740517609654562,-0.20547903817502652,-0.5474201594629304,0.40809011351908236,1.0720060894912629,-0.9804510545643588,-1.0041494608343033,0.5573667616763491,-0.7486017803237077,1.0205517659257686,1.240785529211058,3.149741568733179,1.7394792650550464,1.645661682349741,2.10301243809186,0.5388920140603658,-0.061639706843019025,0.6671420469276572,0.6852623302074585,3.072090978975674,3.2010864353849686,3.1882814967797093,3.588162517641911,-0.2263016271137345,-0.3314804483105227,2.1911393985906495,2.4352981359162196,0.21654186145358403,0.612482250975132,0.31302577253021713,-0.04135865661767714,-0.0009917498407377972,3.8165416179463243,0.7929611203043013,0.11858418117435018,-0.6583511285219581,2.5056210267947026,0.039118345533642226,-0.37406084951540725,-0.021142844948492293,0.3702313895262678,4.433189930630274,0.31302577253021713,1.6141131009311325,2.2926453330472487,1.1060951140545585,0.29384424374464585,0.3512189297429039,1.566526139717696,0.9339209551785153,1.4703817232301912,4.841737850614046,0.5573667616763491,0.2746055190128614,1.5186175105719402,3.213870662525028,2.4352981359162196,0.23595476382188807,-0.4384926181619229,1.8626921049716938,-0.16404228682087726,-0.04135865661767714,1.2740517609654562,1.8167337774526302,-0.4601221695313692,0.8638097235543348,0.6307523498834328,0.09881078799017154 | 3,053 |
Electron transport chain oxphos system in mitochondria | 19 | 50 | 3.080427 | 0.002067 | P12235,O75489,O14949,O75964,Q7KZN9,P03886,P20674,P03915,O43676,P12236,O75306,P22695,P13073,P14406,Q9UDW1,P24539,Q15526,P05141,O75438 | Processes and pathways | WikiPathways | msigdb_wp | 257,384,142,35,43,45,421,304,47,188,195,324,330,85,92,238,244,377,126 | 952,142,47,1177,195,126,384,627,977,35,434,628,1604,978,595,691,45,304,377,1731,1458,1507,257,188,330,85,1298,1889,1831,421,782,324,238,2656,3014,2134,828,1222,2776,2183,783,830,1063,244,2413,650,43,92,747,1053 | 0.15794771197129795,1.9537430602483536,3.072090978975674,-0.0009917498407377972,1.566526139717696,2.1618805177312446,0.7929611203043013,0.4269371803541035,0.13829633186814977,3.2266342617272703,0.7033333538782307,0.4269371803541035,-0.20547903817502652,0.13829633186814977,0.464468695655408,0.3702313895262678,3.0850861706306985,1.0377463366595439,0.8107434624970358,-0.24719447231895844,-0.14342697267853247,-0.16404228682087726,1.2073587193318431,1.6141131009311325,0.9513357791761082,2.5056210267947026,-0.061639706843019025,-0.31030054118727124,-0.28919332161258265,0.7213554512800274,0.29384424374464585,0.9687059891173524,1.3071593288497105,-0.7259104599277266,-1.959204894557855,-0.4169396623740783,0.255309170150584,-0.021142844948492293,-0.8402469607675234,-0.4384926181619229,0.29384424374464585,0.255309170150584,0.07897567452569614,1.2740517609654562,-0.5474201594629304,0.40809011351908236,3.149741568733179,2.4352981359162196,0.3321505284860475,0.09881078799017154 | 3,053 |
Sphingolipid biosynthetic process | 9 | 17 | 3.075221 | 0.002103 | Q99805,Q06136,Q13510,Q16739,Q96G23,Q9P035,P04062,O95470,P27544 | Processes and pathways | GO Biological process | msigdb_gobp | 128,102,40,136,11,218,56,61,159 | 295,1451,61,56,1335,1832,159,2539,102,40,136,549,11,128,998,218,2389 | 1.0720060894912629,-0.14342697267853247,2.780573201657302,2.861170882369116,-0.08198652438815046,-0.28919332161258265,1.7859314470019894,-0.6360002154493802,2.3500331786247033,3.162609148347032,1.998844642307609,0.5388920140603658,4.266395697843969,2.1177736122329143,0.13829633186814977,1.4380399974777385,-0.5254772864924734 | 3,053 |
Organophosphate ester transport | 18 | 28 | 3.072067 | 0.002126 | Q00169,P12235,Q8TB61,Q4KMQ2,P41440,Q9H2D1,Q08722,Q9HC21,Q14108,Q9NV96,Q6NUK1,P61916,Q9BSK2,Q8WTV0,O00400,P05141,P08183,P12236 | Processes and pathways | GO Biological process | msigdb_gobp | 415,257,39,296,362,109,367,339,20,541,534,308,86,26,154,377,349,188 | 154,690,2501,377,349,257,188,1832,2078,362,529,308,415,2539,367,20,296,2874,534,39,26,1023,86,705,109,339,541,2389 | 1.8167337774526302,0.3702313895262678,-0.6137324247371202,0.8107434624970358,0.8989563120030468,1.2073587193318431,1.6141131009311325,-0.28919332161258265,-0.3954626277985668,0.8638097235543348,0.5573667616763491,1.0205517659257686,0.7393289521585672,-0.6360002154493802,0.846167456483267,3.863819674290911,1.0720060894912629,-1.0041494608343033,0.5573667616763491,3.1882814967797093,3.588162517641911,0.11858418117435018,2.5056210267947026,0.3702313895262678,2.2926453330472487,0.9339209551785153,0.5573667616763491,-0.5254772864924734 | 3,053 |
Molecular transducer activity | 19 | 47 | 3.066217 | 0.002168 | Q15375,Q99442,Q14108,Q99720,P36896,P20645,Q8WTV0,Q8IX05,Q15629,Q9BUN8,P15260,Q9UBG0,O15118,O15173,O75787,Q9UNN8,P49327,Q08722,P10586 | Functions | GO Molecular function | msigdb_gomf | 265,409,20,24,152,282,26,293,38,170,299,444,51,67,446,335,229,367,371 | 2215,513,51,67,955,446,1557,1940,1055,2465,371,1508,299,824,282,152,925,2564,1225,229,618,477,2442,367,1383,1691,20,265,38,1630,2542,836,293,26,2201,1805,1972,409,1355,24,170,2423,2851,444,867,335,797 | -0.4601221695313692,0.5757898109834075,3.0329755799706857,2.7127576287713535,0.15794771197129795,0.6852623302074585,-0.18472611797839597,-0.3314804483105227,0.07897567452569614,-0.5915469880276591,0.8284788048032764,-0.16404228682087726,1.0548976876796043,0.255309170150584,1.123076264470747,1.8474051204959177,0.17753878759272398,-0.6583511285219581,-0.021142844948492293,1.3565272843725606,0.4457299111164649,0.6307523498834328,-0.5694431482641074,0.846167456483267,-0.10239964490688236,-0.2263016271137345,3.863819674290911,1.1905844892407613,3.1882814967797093,-0.20547903817502652,-0.6360002154493802,0.255309170150584,1.0890718099012444,3.588162517641911,-0.4384926181619229,-0.2681581692824456,-0.3314804483105227,0.7572541827182976,-0.08198652438815046,3.757058561044739,1.7239281707505134,-0.5474201594629304,-0.9568488266934512,0.7033333538782307,0.23595476382188807,0.9513357791761082,0.29384424374464585 | 3,053 |
Sphingolipid metabolism | 9 | 13 | 3.065874 | 0.00217 | P16278,Q99519,Q06136,P06280,Q16739,Q8TCT0,Q13510,P04062,O95470 | Processes and pathways | KEGG Pathways | msigdb_kegg | 65,132,102,231,136,169,40,56,61 | 295,1451,625,61,56,231,65,102,40,136,169,132,998 | 1.0720060894912629,-0.14342697267853247,0.4269371803541035,2.780573201657302,2.861170882369116,1.3401101108679196,2.739955797601633,2.3500331786247033,3.162609148347032,1.998844642307609,1.7239281707505134,2.0585502205371826,0.13829633186814977 | 3,053 |
Biliary tract abnormality | 9 | 27 | 3.062091 | 0.002198 | Q14739,Q92889,Q5XKP0,O95202,P07602,Q14108,O96028,P09601,P04062 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 41,202,209,148,113,20,181,22,56 | 2928,625,148,181,2771,56,113,22,598,1461,1680,2359,1099,677,1269,1193,20,41,209,202,1645,591,1075,275,970,2907,1720 | -1.1484159978357622,0.4269371803541035,1.893169553532986,1.645661682349741,-0.8402469607675234,2.861170882369116,2.2493125713395874,3.828386645902461,0.464468695655408,-0.14342697267853247,-0.2263016271137345,-0.5254772864924734,0.05907835699925959,0.3891883162351104,-0.04135865661767714,-0.0009917498407377972,3.863819674290911,3.162609148347032,1.4703817232301912,1.5186175105719402,-0.20547903817502652,0.4831539193642934,0.07897567452569614,1.1569131412555997,0.15794771197129795,-1.0758316877354026,-0.2263016271137345 | 3,053 |
Intrinsic component of mitochondrial inner membrane | 18 | 29 | 3.06155 | 0.002202 | Q16134,Q8NE86,Q53H12,Q9BUR5,Q15070,Q13505,Q9UG56,O60830,Q5XKP0,O14925,Q9NVH1,Q9HC21,Q99595,Q9Y512,Q9Y2R0,Q9H3K2,Q6P4A7,Q9NX63 | Localization | GO Cellular component | msigdb_gocc | 189,452,549,262,134,168,200,12,209,146,443,339,23,382,57,127,309,552 | 146,556,12,2909,627,2775,1955,648,168,134,189,886,549,209,309,739,452,890,23,262,127,727,339,443,552,200,57,1409,382 | 1.893169553532986,0.5203652040028177,4.210058257772574,-1.099924828090018,0.4269371803541035,-0.8402469607675234,-0.3314804483105227,0.40809011351908236,1.7239281707505134,2.0138167795559077,1.6141131009311325,0.21654186145358403,0.5388920140603658,1.4703817232301912,1.0205517659257686,0.3321505284860475,0.6852623302074585,0.21654186145358403,3.8165416179463243,1.2073587193318431,2.1325052522465455,0.3512189297429039,0.9339209551785153,0.7033333538782307,0.5388920140603658,1.5346231303445235,2.861170882369116,-0.10239964490688236,0.8107434624970358 | 3,053 |
Cholesterol metabolism with bloch and kandutschrussell pathways | 10 | 21 | 3.056203 | 0.002242 | Q15800,P35610,Q9BWD1,P37268,P49327,Q14739,Q9UBM7,Q14534,Q16850,Q15392 | Processes and pathways | WikiPathways | msigdb_wp | 95,258,5,197,229,41,269,183,60,29 | 999,749,1454,979,1259,1785,258,197,326,229,2920,2574,183,41,1914,29,2280,95,60,5,269 | 0.11858418117435018,0.31302577253021713,-0.14342697267853247,0.13829633186814977,-0.04135865661767714,-0.2681581692824456,1.2073587193318431,1.5505926056196673,0.9687059891173524,1.3565272843725606,-1.1241192412166017,-0.6583511285219581,1.645661682349741,3.162609148347032,-0.31030054118727124,3.4405377784263176,-0.48182900048661537,2.392786822066208,2.794064797575269,4.466159447011184,1.1737693798534528 | 3,053 |
Glycosphingolipid metabolism | 10 | 17 | 3.032382 | 0.002426 | P16278,Q99519,P06280,Q16739,Q8TCT0,Q13510,P07602,P04062,P10619,P17900 | Processes and pathways | Reactome Pathways | msigdb_reactome | 65,132,231,136,169,40,113,56,185,186 | 1030,625,56,231,386,113,2598,185,65,186,40,136,169,132,2419,998,275 | 0.09881078799017154,0.4269371803541035,2.861170882369116,1.3401101108679196,0.7929611203043013,2.2493125713395874,-0.6807859438462549,1.6299048673842986,2.739955797601633,1.6299048673842986,3.162609148347032,1.998844642307609,1.7239281707505134,2.0585502205371826,-0.5474201594629304,0.13829633186814977,1.1569131412555997 | 3,053 |
Oxidative phosphorylation | 20 | 57 | 3.030046 | 0.002445 | O75489,O14949,Q9Y487,O75964,Q7KZN9,P03886,P20674,P03915,O43676,O95168,Q15904,O75306,P22695,Q86Y39,P13073,P14406,Q9UDW1,P24539,Q93050,O75438 | Processes and pathways | KEGG Pathways | msigdb_kegg | 384,142,156,35,43,45,421,304,47,434,318,195,324,204,330,85,92,238,121,126 | 952,142,47,1177,195,126,384,977,35,434,628,1604,978,595,691,45,304,1731,614,1458,1507,330,85,1298,1889,1831,421,1462,2264,782,324,238,2656,3014,2134,828,1222,456,2472,2776,2183,783,830,1063,1470,2575,318,2413,650,43,204,121,2800,92,2209,156,1053 | 0.15794771197129795,1.9537430602483536,3.072090978975674,-0.0009917498407377972,1.566526139717696,2.1618805177312446,0.7929611203043013,0.13829633186814977,3.2266342617272703,0.7033333538782307,0.4269371803541035,-0.20547903817502652,0.13829633186814977,0.464468695655408,0.3702313895262678,3.0850861706306985,1.0377463366595439,-0.24719447231895844,0.4457299111164649,-0.14342697267853247,-0.16404228682087726,0.9513357791761082,2.5056210267947026,-0.061639706843019025,-0.31030054118727124,-0.28919332161258265,0.7213554512800274,-0.14342697267853247,-0.48182900048661537,0.29384424374464585,0.9687059891173524,1.3071593288497105,-0.7259104599277266,-1.959204894557855,-0.4169396623740783,0.255309170150584,-0.021142844948492293,0.6671420469276572,-0.5915469880276591,-0.8402469607675234,-0.4384926181619229,0.29384424374464585,0.255309170150584,0.07897567452569614,-0.14342697267853247,-0.6583511285219581,0.9860318695770233,-0.5474201594629304,0.40809011351908236,3.149741568733179,1.502575541135129,2.1911393985906495,-0.8633825363003653,2.4352981359162196,-0.4384926181619229,1.8167337774526302,0.09881078799017154 | 3,053 |
Intrinsic component of mitochondrial membrane | 23 | 41 | 3.026654 | 0.002473 | Q9BUR5,Q15070,P12235,O60830,Q8IWA4,O14925,Q99595,Q9NX63,Q53H12,Q13505,Q9NVH1,O43819,Q6P4A7,Q9Y2R0,Q16134,Q8NE86,Q9UG56,Q5XKP0,Q9HC21,O96008,Q9Y512,O75880,Q9H3K2 | Localization | GO Cellular component | msigdb_gocc | 262,134,257,12,407,146,23,552,549,168,443,556,309,57,189,452,200,209,339,613,382,627,127 | 146,556,12,2909,627,1778,613,257,2775,1955,959,648,168,134,1105,189,886,549,209,309,739,407,1197,1700,452,1804,890,23,1494,262,967,127,727,339,443,552,200,2424,57,1409,382 | 1.893169553532986,0.5203652040028177,4.210058257772574,-1.099924828090018,0.4269371803541035,-0.2681581692824456,0.4457299111164649,1.2073587193318431,-0.8402469607675234,-0.3314804483105227,0.15794771197129795,0.40809011351908236,1.7239281707505134,2.0138167795559077,0.05907835699925959,1.6141131009311325,0.21654186145358403,0.5388920140603658,1.4703817232301912,1.0205517659257686,0.3321505284860475,0.7572541827182976,-0.0009917498407377972,-0.2263016271137345,0.6852623302074585,-0.2681581692824456,0.21654186145358403,3.8165416179463243,-0.14342697267853247,1.2073587193318431,0.15794771197129795,2.1325052522465455,0.3512189297429039,0.9339209551785153,0.7033333538782307,0.5388920140603658,1.5346231303445235,-0.5474201594629304,2.861170882369116,-0.10239964490688236,0.8107434624970358 | 3,053 |
Proton transmembrane transporter activity | 15 | 36 | 3.017656 | 0.002547 | O75964,P12235,Q96ES6,Q7KZN9,P20674,P13073,Q9UDW1,P24539,O95202,Q15526,Q93050,Q13423,Q9Y487,O00400,P05141 | Functions | GO Molecular function | msigdb_gomf | 35,257,91,43,421,330,92,238,148,244,121,88,156,154,377 | 154,977,35,148,691,377,1731,614,1507,257,330,421,1462,2264,238,2656,828,1222,456,2472,2776,927,830,1063,1470,648,88,244,43,1704,121,91,793,92,2209,156 | 1.8167337774526302,0.13829633186814977,3.2266342617272703,1.893169553532986,0.3702313895262678,0.8107434624970358,-0.24719447231895844,0.4457299111164649,-0.16404228682087726,1.2073587193318431,0.9513357791761082,0.7213554512800274,-0.14342697267853247,-0.48182900048661537,1.3071593288497105,-0.7259104599277266,0.255309170150584,-0.021142844948492293,0.6671420469276572,-0.5915469880276591,-0.8402469607675234,0.17753878759272398,0.255309170150584,0.07897567452569614,-0.14342697267853247,0.40809011351908236,2.4916088032578028,1.2740517609654562,3.149741568733179,-0.2263016271137345,2.1911393985906495,2.4352981359162196,0.29384424374464585,2.4352981359162196,-0.4384926181619229,1.8167337774526302 | 3,053 |
Steroid metabolism | 11 | 26 | 2.992004 | 0.002772 | Q15800,Q06520,P35610,P37268,Q14739,Q9UBM7,O15118,Q9H2C2,P04062,Q16850,Q15392 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 95,4,258,197,41,269,51,192,56,60,29 | 51,2175,1826,2501,56,571,1259,2533,258,197,308,618,2680,2920,4,2574,41,1914,29,2280,95,60,2712,192,269,2648 | 3.0329755799706857,-0.4384926181619229,-0.28919332161258265,-0.6137324247371202,2.861170882369116,0.5017859632503069,-0.04135865661767714,-0.6360002154493802,1.2073587193318431,1.5505926056196673,1.0205517659257686,0.4457299111164649,-0.7486017803237077,-1.1241192412166017,4.564311687934693,-0.6583511285219581,3.162609148347032,-0.31030054118727124,3.4405377784263176,-0.48182900048661537,2.392786822066208,2.794064797575269,-0.7713802427604488,1.6141131009311325,1.1737693798534528,-0.7033054530869399 | 3,053 |
Inorganic anion transport | 16 | 27 | 2.973328 | 0.002946 | P21796,Q9UBX3,Q9C0H2,Q4KMQ2,P0CG08,Q9H0H5,P54105,P45880,P04920,Q9Y277,Q9UHG3,Q9Y6M7,Q02978,O43681,Q9H813,P08183 | Processes and pathways | GO Biological process | msigdb_gobp | 2,36,6,296,572,592,493,15,305,245,54,487,531,625,287,349 | 2023,625,305,349,572,2,15,927,1152,493,1010,648,531,1389,296,2859,2874,767,1244,6,592,287,814,36,54,245,487 | -0.37406084951540725,0.4269371803541035,1.0377463366595439,0.8989563120030468,0.5017859632503069,4.914940523522634,4.096236762872413,0.17753878759272398,0.019095144049973707,0.612482250975132,0.11858418117435018,0.40809011351908236,0.5573667616763491,-0.10239964490688236,1.0720060894912629,-0.9804510545643588,-1.0041494608343033,0.31302577253021713,-0.021142844948492293,4.433189930630274,0.4831539193642934,1.1060951140545585,0.2746055190128614,3.213870662525028,2.980515400984891,1.2740517609654562,0.6307523498834328 | 3,053 |
Mitochondrial respiratory chain complex assembly | 17 | 36 | 2.96049 | 0.003071 | O75306,Q15070,Q9P0J0,O75489,Q6DKK2,P03886,Q86Y39,P03915,Q9H061,O43676,Q15526,Q9BSK2,Q9Y512,Q96CU9,O95831,O75438,Q9Y2R0 | Processes and pathways | GO Biological process | msigdb_gobp | 195,134,203,384,140,45,204,304,50,47,244,86,382,281,435,126,57 | 47,556,1177,195,126,384,627,434,628,978,435,595,45,304,3014,783,832,134,244,2413,650,140,1637,204,281,1650,86,1442,50,1050,2522,203,2907,57,382,1053 | 3.072090978975674,0.5203652040028177,-0.0009917498407377972,1.566526139717696,2.1618805177312446,0.7929611203043013,0.4269371803541035,0.7033333538782307,0.4269371803541035,0.13829633186814977,0.7033333538782307,0.464468695655408,3.0850861706306985,1.0377463366595439,-1.959204894557855,0.29384424374464585,0.255309170150584,2.0138167795559077,1.2740517609654562,-0.5474201594629304,0.40809011351908236,1.9688079417064501,-0.20547903817502652,1.502575541135129,1.1400155210794878,-0.20547903817502652,2.5056210267947026,-0.12287961106727112,3.072090978975674,0.09881078799017154,-0.6137324247371202,1.5186175105719402,-1.0758316877354026,2.861170882369116,0.8107434624970358,0.09881078799017154 | 3,053 |
Protein localization | 16 | 70 | 2.948409 | 0.003194 | Q8N4H5,P21796,Q9NS69,Q15067,Q5JRX3,Q13505,P39210,P51648,O60830,O14925,Q99595,P46379,P09601,Q9UJS0,O00116,P12236 | Processes and pathways | Reactome Pathways | msigdb_reactome | 64,2,3,259,164,168,105,138,12,146,23,52,22,151,119,188 | 119,146,1822,527,625,1295,690,12,488,2787,2909,2128,2499,819,663,1778,628,613,847,1731,614,2528,22,2829,257,188,2074,2,2078,2656,694,325,2883,2775,105,543,52,899,2359,1126,138,1099,2818,677,2636,495,168,259,1105,986,164,533,2543,64,1313,1804,1645,23,2783,2862,2949,3,552,2389,841,151,2907,2254,382,2255 | 2.1911393985906495,1.893169553532986,-0.28919332161258265,0.5573667616763491,0.4269371803541035,-0.061639706843019025,0.3702313895262678,4.210058257772574,0.612482250975132,-0.8633825363003653,-1.099924828090018,-0.4169396623740783,-0.6137324247371202,0.255309170150584,0.3891883162351104,-0.2681581692824456,0.4269371803541035,0.4457299111164649,0.23595476382188807,-0.24719447231895844,0.4457299111164649,-0.6360002154493802,3.828386645902461,-0.9333418075172426,1.2073587193318431,1.6141131009311325,-0.3954626277985668,4.914940523522634,-0.3954626277985668,-0.7259104599277266,0.3702313895262678,0.9687059891173524,-1.0279450311062537,-0.8402469607675234,2.3213944057139972,0.5388920140603658,3.006789555372895,0.1970700191478118,-0.5254772864924734,0.039118345533642226,1.9688079417064501,0.05907835699925959,-0.9099290428795153,0.3891883162351104,-0.7033054530869399,0.612482250975132,1.7239281707505134,1.2073587193318431,0.05907835699925959,0.13829633186814977,1.7704807226942911,0.5573667616763491,-0.6360002154493802,2.7535188063677927,-0.061639706843019025,-0.2681581692824456,-0.20547903817502652,3.8165416179463243,-0.8402469607675234,-0.9804510545643588,-1.2219313118513195,4.841737850614046,0.5388920140603658,-0.5254772864924734,0.255309170150584,1.8626921049716938,-1.0758316877354026,-0.4601221695313692,0.8107434624970358,-0.4601221695313692 | 3,053 |
Abnormality of femur morphology | 27 | 68 | 2.940606 | 0.003276 | O00754,Q9NZJ7,Q96HY6,Q7LGA3,Q9Y487,Q14739,P15260,Q96A33,O75718,P04062,O95831,P16278,P16435,P04066,O75844,Q92889,Q9UHX1,Q96AY3,Q7RTS9,Q6NUQ1,P06280,Q9BV10,Q9Y619,Q9BXW9,P07602,Q99575,O00116 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 383,275,400,279,156,41,299,306,180,56,435,65,323,454,72,202,81,338,354,227,231,103,365,364,113,507,119 | 119,2428,2804,383,1987,2952,2431,2909,1777,180,72,1882,435,1556,2771,56,454,2352,231,113,299,65,323,2815,1006,1736,2728,2775,2791,1373,2359,1152,1153,2270,1010,2187,757,41,1754,1194,736,1069,227,2782,279,354,2687,1166,2051,1533,202,306,338,400,2689,507,103,364,1654,2493,524,1811,275,81,2343,156,1363,365 | 2.1911393985906495,-0.5694431482641074,-0.8866095938314523,0.7929611203043013,-0.35273367187282356,-1.2466485207088316,-0.5694431482641074,-1.099924828090018,-0.2681581692824456,1.645661682349741,2.658069675513038,-0.31030054118727124,0.7033333538782307,-0.18472611797839597,-0.8402469607675234,2.861170882369116,0.6671420469276572,-0.5254772864924734,1.3401101108679196,2.2493125713395874,1.0548976876796043,2.739955797601633,0.9687059891173524,-0.9099290428795153,0.11858418117435018,-0.24719447231895844,-0.7942466885201216,-0.8402469607675234,-0.8633825363003653,-0.10239964490688236,-0.5254772864924734,0.019095144049973707,0.019095144049973707,-0.48182900048661537,0.11858418117435018,-0.4384926181619229,0.31302577253021713,3.162609148347032,-0.24719447231895844,-0.0009917498407377972,0.3321505284860475,0.07897567452569614,1.372905949710868,-0.8402469607675234,1.1400155210794878,0.8989563120030468,-0.7486017803237077,0.019095144049973707,-0.37406084951540725,-0.16404228682087726,1.5186175105719402,1.0377463366595439,0.9339209551785153,0.7751314656744809,-0.7486017803237077,0.5941615220565629,2.3500331786247033,0.8638097235543348,-0.20547903817502652,-0.5915469880276591,0.5757898109834075,-0.2681581692824456,1.1569131412555997,2.5614117640389127,-0.5036138048570713,1.8167337774526302,-0.08198652438815046,0.8638097235543348 | 3,053 |
Sterol binding | 7 | 15 | 2.937788 | 0.003306 | P21796,O95772,P35610,P45880,O15118,Q14108,Q14849 | Functions | GO Molecular function | msigdb_gomf | 2,68,258,15,51,20,30 | 51,2175,68,2353,2,1832,2078,258,15,308,20,30,1284,2059,705 | 3.0329755799706857,-0.4384926181619229,2.685462544005469,-0.5254772864924734,4.914940523522634,-0.28919332161258265,-0.3954626277985668,1.2073587193318431,4.096236762872413,1.0205517659257686,3.863819674290911,3.428112577652922,-0.04135865661767714,-0.37406084951540725,0.3702313895262678 | 3,053 |
Mitochondrial carrier domain superfamily [IPR023395] | 13 | 20 | 2.930057 | 0.003389 | Q6NUK1,Q9UBX3,P12235,Q9Y619,Q9H2D1,Q9NZJ7,O43772,Q9HC21,Q9BSK2,Q9UJS0,Q70HW3,P05141,P12236 | Sequence | InterPro Superfamily | interpro_homologous_superfamily | 534,36,257,365,109,275,241,339,86,151,251,377,188 | 241,690,819,377,257,188,1101,648,531,534,251,86,109,793,339,275,36,151,365,971 | 1.2740517609654562,0.3702313895262678,0.255309170150584,0.8107434624970358,1.2073587193318431,1.6141131009311325,0.05907835699925959,0.40809011351908236,0.5573667616763491,0.5573667616763491,1.240785529211058,2.5056210267947026,2.2926453330472487,0.29384424374464585,0.9339209551785153,1.1569131412555997,3.213870662525028,1.8626921049716938,0.8638097235543348,0.15794771197129795 | 3,053 |
SLC25 family of mitochondrial transporters | 13 | 20 | 2.930057 | 0.003389 | Q6NUK1,Q9UBX3,P12235,Q9Y619,Q9H2D1,Q9NZJ7,O43772,Q9HC21,Q9BSK2,Q9UJS0,Q70HW3,P05141,P12236 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 534,36,257,365,109,275,241,339,86,151,251,377,188 | 241,690,819,377,257,188,1101,648,531,534,251,86,109,793,339,275,36,151,365,971 | 1.2740517609654562,0.3702313895262678,0.255309170150584,0.8107434624970358,1.2073587193318431,1.6141131009311325,0.05907835699925959,0.40809011351908236,0.5573667616763491,0.5573667616763491,1.240785529211058,2.5056210267947026,2.2926453330472487,0.29384424374464585,0.9339209551785153,1.1569131412555997,3.213870662525028,1.8626921049716938,0.8638097235543348,0.15794771197129795 | 3,053 |
Mitochondrial substrate/solute carrier [IPR018108] | 13 | 20 | 2.930057 | 0.003389 | Q6NUK1,Q9UBX3,P12235,Q9Y619,Q9H2D1,Q9NZJ7,O43772,Q9HC21,Q9BSK2,Q9UJS0,Q70HW3,P05141,P12236 | Sequence | InterPro Repeat | interpro_repeat | 534,36,257,365,109,275,241,339,86,151,251,377,188 | 241,690,819,377,257,188,1101,648,531,534,251,86,109,793,339,275,36,151,365,971 | 1.2740517609654562,0.3702313895262678,0.255309170150584,0.8107434624970358,1.2073587193318431,1.6141131009311325,0.05907835699925959,0.40809011351908236,0.5573667616763491,0.5573667616763491,1.240785529211058,2.5056210267947026,2.2926453330472487,0.29384424374464585,0.9339209551785153,1.1569131412555997,3.213870662525028,1.8626921049716938,0.8638097235543348,0.15794771197129795 | 3,053 |
Intrinsic component of endoplasmic reticulum membrane | 17 | 48 | 2.928132 | 0.00341 | Q86XL3,Q9Y4P3,Q15629,O76024,Q8TB61,O75844,Q9BUN8,Q9H490,Q9UBM7,Q9Y282,Q8TCT8,Q8TCT9,Q9NZ01,Q9P035,O95470,Q9NQC3,P57088 | Localization | GO Cellular component | msigdb_gocc | 33,228,38,256,39,72,170,106,269,141,143,179,115,218,61,123,285 | 1030,999,729,1294,72,256,61,2653,692,597,2702,502,2808,674,285,733,424,2370,2010,38,2874,2513,33,550,1044,39,143,179,944,2823,723,306,2584,409,2419,170,106,499,2591,123,115,218,2851,269,1546,141,228,1364 | 0.09881078799017154,0.11858418117435018,0.3321505284860475,-0.061639706843019025,2.658069675513038,1.2073587193318431,2.780573201657302,-0.7259104599277266,0.3702313895262678,0.464468695655408,-0.7713802427604488,0.5941615220565629,-0.8866095938314523,0.3891883162351104,1.1060951140545585,0.3321505284860475,0.7213554512800274,-0.5254772864924734,-0.35273367187282356,3.1882814967797093,-1.0041494608343033,-0.6137324247371202,3.3405919169416305,0.5388920140603658,0.09881078799017154,3.1882814967797093,1.9537430602483536,1.661383738534994,0.17753878759272398,-0.9099290428795153,0.3512189297429039,1.0377463366595439,-0.6583511285219581,0.7572541827182976,-0.5474201594629304,1.7239281707505134,2.3213944057139972,0.612482250975132,-0.6583511285219581,2.1765244342071473,2.2348120000348723,1.4380399974777385,-0.9568488266934512,1.1737693798534528,-0.16404228682087726,1.9688079417064501,1.372905949710868,-0.08198652438815046 | 3,053 |
Disproportionate short stature | 10 | 24 | 2.927897 | 0.003413 | P16278,O00116,Q9BV10,Q14739,Q9UBM7,Q9UHX1,O75718,Q7LGA3,Q7RTS9,Q15392 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 65,119,103,41,269,81,180,279,354,29 | 119,1822,2431,180,752,65,1892,631,1373,1522,1796,41,1754,29,736,678,279,354,1533,400,2741,103,269,81 | 2.1911393985906495,-0.28919332161258265,-0.5694431482641074,1.645661682349741,0.31302577253021713,2.739955797601633,-0.31030054118727124,0.4269371803541035,-0.10239964490688236,-0.16404228682087726,-0.2681581692824456,3.162609148347032,-0.24719447231895844,3.4405377784263176,0.3321505284860475,0.3891883162351104,1.1400155210794878,0.8989563120030468,-0.16404228682087726,0.7751314656744809,-0.7942466885201216,2.3500331786247033,1.1737693798534528,2.5614117640389127 | 3,053 |
Endoplasmic reticulum golgi intermediate compartment membrane | 12 | 25 | 2.925971 | 0.003434 | Q15904,P24390,Q12907,Q9Y3B3,Q13190,Q15363,Q9Y282,O15260,Q03518,O95070,Q10472,Q8N511 | Localization | GO Cellular component | msigdb_gocc | 318,1,426,69,495,139,141,110,424,370,373,58 | 110,612,1671,370,1,1610,2702,926,544,674,1127,1307,424,373,426,495,139,318,58,723,2058,1170,141,1771,69 | 2.278229101219084,0.4457299111164649,-0.2263016271137345,0.8284788048032764,5.242039873099177,-0.20547903817502652,-0.7713802427604488,0.17753878759272398,0.5388920140603658,0.3891883162351104,0.039118345533642226,-0.061639706843019025,0.7213554512800274,0.8284788048032764,0.7213554512800274,0.612482250975132,1.9688079417064501,0.9860318695770233,2.834398419466517,0.3512189297429039,-0.37406084951540725,0.019095144049973707,1.9688079417064501,-0.24719447231895844,2.685462544005469 | 3,053 |
Alcohol binding | 8 | 14 | 2.911793 | 0.003594 | P21796,O95772,P35610,P45880,O15118,Q14108,P61916,Q14849 | Functions | GO Molecular function | msigdb_gomf | 2,68,258,15,51,20,308,30 | 322,51,1775,2175,68,2353,2,2078,258,15,308,20,30,705 | 0.9687059891173524,3.0329755799706857,-0.2681581692824456,-0.4384926181619229,2.685462544005469,-0.5254772864924734,4.914940523522634,-0.3954626277985668,1.2073587193318431,4.096236762872413,1.0205517659257686,3.863819674290911,3.428112577652922,0.3702313895262678 | 3,053 |
Golgi associated vesicle membrane | 7 | 22 | 2.90071 | 0.003723 | P24390,Q9Y3B3,O43731,Q15363,Q8TCT8,Q8IUH4,Q8N511 | Localization | GO Cellular component | msigdb_gocc | 1,69,7,139,143,184,58 | 871,7,1667,2983,629,1559,1,829,1373,2476,1898,1377,1792,139,184,58,143,635,2338,239,69,1933 | 0.21654186145358403,4.366865380443215,-0.2263016271137345,-1.4741094280213356,0.4269371803541035,-0.18472611797839597,5.242039873099177,0.255309170150584,-0.10239964490688236,-0.5915469880276591,-0.31030054118727124,-0.10239964490688236,-0.2681581692824456,1.9688079417064501,1.645661682349741,2.834398419466517,1.9537430602483536,0.4269371803541035,-0.5036138048570713,1.3071593288497105,2.685462544005469,-0.31030054118727124 | 3,053 |
Protein localization to endoplasmic reticulum | 12 | 36 | 2.894952 | 0.003792 | P61009,P24390,O15258,O43731,Q15629,Q9Y5M8,Q96HY6,Q9UHB9,Q99442,P46379,Q9NQC3,Q15005 | Processes and pathways | GO Biological process | msigdb_gobp | 291,1,294,7,38,70,400,82,409,52,123,416 | 1772,294,729,625,7,1295,1085,1672,1219,1,1058,2082,52,1060,674,2818,2631,291,2187,2041,733,416,2145,38,1270,2543,1920,400,409,2159,123,2389,867,82,430,70 | -0.2681581692824456,1.0720060894912629,0.3321505284860475,0.4269371803541035,4.366865380443215,-0.061639706843019025,0.05907835699925959,-0.2263016271137345,-0.021142844948492293,5.242039873099177,0.07897567452569614,-0.3954626277985668,3.006789555372895,0.07897567452569614,0.3891883162351104,-0.9099290428795153,-0.7033054530869399,1.0890718099012444,-0.4384926181619229,-0.37406084951540725,0.3321505284860475,0.7393289521585672,-0.4169396623740783,3.1882814967797093,-0.04135865661767714,-0.6360002154493802,-0.31030054118727124,0.7751314656744809,0.7572541827182976,-0.4169396623740783,2.1765244342071473,-0.5254772864924734,0.23595476382188807,2.547502565728995,0.7213554512800274,2.685462544005469 | 3,053 |
Primary active transmembrane transporter activity | 19 | 49 | 2.893845 | 0.003806 | P05023,O75489,Q7KZN9,P03886,P20674,Q03518,P03915,O43676,P16615,O95168,O75306,Q9P0J0,P20020,P13073,Q9HD20,Q9UDW1,P08183,Q15526,O75438 | Functions | GO Molecular function | msigdb_gomf | 264,384,43,45,421,424,304,47,436,434,195,203,331,330,211,92,349,244,126 | 952,1250,47,1369,1177,195,126,384,434,628,1604,978,595,691,45,304,264,1731,349,614,1507,330,436,1831,331,421,1462,2264,694,3014,828,456,2472,2183,1152,783,1470,424,757,1105,244,2413,650,43,211,203,92,2209,1053 | 0.15794771197129795,-0.04135865661767714,3.072090978975674,-0.10239964490688236,-0.0009917498407377972,1.566526139717696,2.1618805177312446,0.7929611203043013,0.7033333538782307,0.4269371803541035,-0.20547903817502652,0.13829633186814977,0.464468695655408,0.3702313895262678,3.0850861706306985,1.0377463366595439,1.1905844892407613,-0.24719447231895844,0.8989563120030468,0.4457299111164649,-0.16404228682087726,0.9513357791761082,0.7033333538782307,-0.28919332161258265,0.9513357791761082,0.7213554512800274,-0.14342697267853247,-0.48182900048661537,0.3702313895262678,-1.959204894557855,0.255309170150584,0.6671420469276572,-0.5915469880276591,-0.4384926181619229,0.019095144049973707,0.29384424374464585,-0.14342697267853247,0.7213554512800274,0.31302577253021713,0.05907835699925959,1.2740517609654562,-0.5474201594629304,0.40809011351908236,3.149741568733179,1.4703817232301912,1.5186175105719402,2.4352981359162196,-0.4384926181619229,0.09881078799017154 | 3,053 |
Lipid biosynthesis | 19 | 47 | 2.889294 | 0.003861 | Q16739,Q96G23,Q9UBM7,Q53GQ0,Q15392,P27544,Q14739,Q96N66,Q16850,O14735,P37268,Q9UG56,Q9P035,Q15800,P49327,Q9NZ01,O00116,Q9NRX5,P35790 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 136,11,269,283,29,159,41,175,60,322,197,200,218,95,229,115,119,124,255 | 119,2997,999,322,846,979,1826,3039,1259,159,255,197,2728,326,672,229,1743,1062,2920,3031,2574,41,1914,858,29,2280,95,136,60,283,590,741,1045,11,175,1115,1539,1138,2492,2862,481,1319,124,115,218,269,200 | 2.1911393985906495,-1.657669459103611,0.11858418117435018,0.9687059891173524,0.23595476382188807,0.13829633186814977,-0.28919332161258265,-2.950743519269414,-0.04135865661767714,1.7859314470019894,1.2240923176202834,1.5505926056196673,-0.7942466885201216,0.9687059891173524,0.3891883162351104,1.3565272843725606,-0.24719447231895844,0.07897567452569614,-1.1241192412166017,-2.493024635127748,-0.6583511285219581,3.162609148347032,-0.31030054118727124,0.23595476382188807,3.4405377784263176,-0.48182900048661537,2.392786822066208,1.998844642307609,2.794064797575269,1.123076264470747,0.4831539193642934,0.3321505284860475,0.09881078799017154,4.266395697843969,1.6770712269532793,0.05907835699925959,-0.16404228682087726,0.039118345533642226,-0.5915469880276591,-0.9804510545643588,0.6307523498834328,-0.061639706843019025,2.1765244342071473,2.2348120000348723,1.4380399974777385,1.1737693798534528,1.5346231303445235 | 3,053 |
er | 34 | 83 | 2.882868 | 0.003941 | Q9Y6B6,Q15363,Q5HYI8,Q969Q5,O75915,O96005,Q9Y487,O00400,Q15392,O60499,Q8N4V1,O00264,O15269,Q14739,P46977,Q6DD88,Q96N66,Q96A33,Q16850,O95470,Q07065,O14735,O15173,Q9Y5M8,P48449,Q8NHH9,Q8TCJ2,Q9NR31,Q06136,Q13190,P18085,Q9P2W9,Q9NQC3,P27824 | Localization | OpenCell Localization | opencell_localization | 397,139,518,540,271,150,156,154,29,157,550,288,295,41,423,301,175,306,60,61,317,322,67,70,326,337,467,483,102,495,243,118,123,502 | 288,154,999,322,67,295,1451,1294,157,896,1671,271,1993,61,846,150,1556,1826,821,751,1672,243,1834,502,2034,423,326,672,544,1305,1374,674,2569,2818,2187,1307,2041,3029,1380,102,317,2777,495,41,2010,139,29,2280,717,60,518,301,2686,550,1044,1166,741,337,467,2846,2288,540,1022,306,175,2419,1138,705,1025,3032,1400,2591,123,483,744,2389,118,1546,2065,1081,156,70,397 | 1.0890718099012444,1.8167337774526302,0.11858418117435018,0.9687059891173524,2.7127576287713535,1.0720060894912629,-0.14342697267853247,-0.061639706843019025,1.8013490730391473,0.1970700191478118,-0.2263016271137345,1.1569131412555997,-0.35273367187282356,2.780573201657302,0.23595476382188807,1.8779468595500388,-0.18472611797839597,-0.28919332161258265,0.255309170150584,0.31302577253021713,-0.2263016271137345,1.2740517609654562,-0.28919332161258265,0.5941615220565629,-0.37406084951540725,0.7213554512800274,0.9687059891173524,0.3891883162351104,0.5388920140603658,-0.061639706843019025,-0.10239964490688236,0.3891883162351104,-0.6583511285219581,-0.9099290428795153,-0.4384926181619229,-0.061639706843019025,-0.37406084951540725,-2.461872152530897,-0.10239964490688236,2.3500331786247033,0.9860318695770233,-0.8402469607675234,0.612482250975132,3.162609148347032,-0.35273367187282356,1.9688079417064501,3.4405377784263176,-0.48182900048661537,0.3512189297429039,2.794064797575269,0.5757898109834075,1.0548976876796043,-0.7486017803237077,0.5388920140603658,0.09881078799017154,0.019095144049973707,0.3321505284860475,0.9339209551785153,0.6489721670503341,-0.9568488266934512,-0.48182900048661537,0.5573667616763491,0.11858418117435018,1.0377463366595439,1.6770712269532793,-0.5474201594629304,0.039118345533642226,0.3702313895262678,0.11858418117435018,-2.5559115400855172,-0.10239964490688236,-0.6583511285219581,2.1765244342071473,0.6307523498834328,0.3321505284860475,-0.5254772864924734,2.2057255535259004,-0.16404228682087726,-0.37406084951540725,0.07897567452569614,1.8167337774526302,2.685462544005469,0.7929611203043013 | 3,053 |
Regulation of cellular ph | 13 | 24 | 2.875583 | 0.004033 | Q15904,Q9P0T7,Q9HC07,O75787,Q14964,P50897,P04920,Q92544,Q93050,Q9Y6M7,Q8N511,Q9Y487,O75503 | Processes and pathways | GO Biological process | msigdb_gobp | 318,396,196,446,388,27,305,538,121,487,58,156,158 | 158,446,305,1731,572,2079,1736,27,1098,927,1470,388,318,58,538,1704,121,861,196,396,708,2209,156,487 | 1.8013490730391473,0.6852623302074585,1.0377463366595439,-0.24719447231895844,0.5017859632503069,-0.3954626277985668,-0.24719447231895844,3.5515088405121995,0.05907835699925959,0.17753878759272398,-0.14342697267853247,0.7929611203043013,0.9860318695770233,2.834398419466517,0.5573667616763491,-0.2263016271137345,2.1911393985906495,0.23595476382188807,1.566526139717696,0.7929611203043013,0.3702313895262678,-0.4384926181619229,1.8167337774526302,0.6307523498834328 | 3,053 |
Regulation of ph | 13 | 24 | 2.875583 | 0.004033 | Q15904,Q9P0T7,Q9HC07,O75787,Q14964,P50897,P04920,Q92544,Q93050,Q9Y6M7,Q8N511,Q9Y487,O75503 | Processes and pathways | GO Biological process | msigdb_gobp | 318,396,196,446,388,27,305,538,121,487,58,156,158 | 158,446,305,1731,572,2079,1736,27,1098,927,1470,388,318,58,538,1704,121,861,196,396,708,2209,156,487 | 1.8013490730391473,0.6852623302074585,1.0377463366595439,-0.24719447231895844,0.5017859632503069,-0.3954626277985668,-0.24719447231895844,3.5515088405121995,0.05907835699925959,0.17753878759272398,-0.14342697267853247,0.7929611203043013,0.9860318695770233,2.834398419466517,0.5573667616763491,-0.2263016271137345,2.1911393985906495,0.23595476382188807,1.566526139717696,0.7929611203043013,0.3702313895262678,-0.4384926181619229,1.8167337774526302,0.6307523498834328 | 3,053 |
Sphingolipid metabolism | 8 | 10 | 2.868219 | 0.004128 | Q06136,Q16739,Q13510,P07602,Q9NZ01,P04062,P17900,O95470 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 102,136,40,113,115,56,186,61 | 295,1451,61,56,113,186,102,40,136,115 | 1.0720060894912629,-0.14342697267853247,2.780573201657302,2.861170882369116,2.2493125713395874,1.6299048673842986,2.3500331786247033,3.162609148347032,1.998844642307609,2.2348120000348723 | 3,053 |
Sphingolipid pathway | 8 | 11 | 2.866393 | 0.004152 | Q06136,Q16739,Q8TCT0,Q13510,Q96G23,P04062,Q9NRX5,O95470 | Processes and pathways | WikiPathways | msigdb_wp | 102,136,169,40,11,56,124,61 | 295,1451,61,56,2632,102,40,136,169,11,124 | 1.0720060894912629,-0.14342697267853247,2.780573201657302,2.861170882369116,-0.7033054530869399,2.3500331786247033,3.162609148347032,1.998844642307609,1.7239281707505134,4.266395697843969,2.1765244342071473 | 3,053 |
Cholesterol biosynthesis | 9 | 15 | 2.863442 | 0.004191 | Q15800,P37268,Q9BWD1,Q14739,Q9UBM7,Q15392,Q14534,Q16850,Q9H2C2 | Processes and pathways | Reactome Pathways | msigdb_reactome | 95,197,5,41,269,29,183,60,192 | 1259,197,326,2920,2574,183,41,1914,29,2280,95,60,5,192,269 | -0.04135865661767714,1.5505926056196673,0.9687059891173524,-1.1241192412166017,-0.6583511285219581,1.645661682349741,3.162609148347032,-0.31030054118727124,3.4405377784263176,-0.48182900048661537,2.392786822066208,2.794064797575269,4.466159447011184,1.6141131009311325,1.1737693798534528 | 3,053 |
Tetrapyrrole binding | 8 | 16 | 2.860578 | 0.004229 | P53701,O15173,O00264,Q7KZN9,P09601,P30519,Q16850,O43169 | Functions | GO Molecular function | msigdb_gomf | 160,67,288,43,22,25,60,31 | 288,67,31,614,22,2077,25,160,60,43,2488,307,742,481,1867,636 | 1.0890718099012444,2.7127576287713535,3.4032042415630985,0.4457299111164649,3.828386645902461,-0.3954626277985668,3.673048611757954,1.7859314470019894,2.794064797575269,3.149741568733179,-0.5915469880276591,1.0377463366595439,0.3321505284860475,0.6307523498834328,-0.28919332161258265,0.4269371803541035 | 3,053 |
Ascites | 9 | 27 | 2.857927 | 0.004264 | Q99519,Q13510,Q14739,Q92889,O15118,Q14108,P61916,P04062,Q01844 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 132,40,41,202,51,20,308,56,378 | 51,2304,1329,446,56,596,752,1004,630,1673,2898,731,1099,308,1618,2321,832,378,1269,40,20,41,1584,202,132,1075,1720 | 3.0329755799706857,-0.5036138048570713,-0.08198652438815046,0.6852623302074585,2.861170882369116,0.464468695655408,0.31302577253021713,0.11858418117435018,0.4269371803541035,-0.2263016271137345,-1.0758316877354026,0.3321505284860475,0.05907835699925959,1.0205517659257686,-0.20547903817502652,-0.5036138048570713,0.255309170150584,0.8107434624970358,-0.04135865661767714,3.162609148347032,3.863819674290911,3.162609148347032,-0.18472611797839597,1.5186175105719402,2.0585502205371826,0.07897567452569614,-0.2263016271137345 | 3,053 |
Abnormal retinal artery morphology | 12 | 23 | 2.857413 | 0.004271 | P16278,Q9Y4P3,Q99519,P54198,Q13510,P21964,P03886,Q9NZJ7,P03915,P07602,P10619,P17900 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 65,228,132,133,40,387,45,275,304,113,185,186 | 1666,45,304,386,113,2598,185,2260,65,186,387,2601,1841,133,2537,40,1428,2967,1315,132,275,1769,228 | -0.2263016271137345,3.0850861706306985,1.0377463366595439,0.7929611203043013,2.2493125713395874,-0.6807859438462549,1.6299048673842986,-0.48182900048661537,2.739955797601633,1.6299048673842986,0.7929611203043013,-0.6807859438462549,-0.28919332161258265,2.0138167795559077,-0.6360002154493802,3.162609148347032,-0.12287961106727112,-1.3214527911775553,-0.061639706843019025,2.0585502205371826,1.1569131412555997,-0.24719447231895844,1.372905949710868 | 3,053 |
Abnormal circulating cholesterol concentration | 14 | 33 | 2.844966 | 0.004442 | Q9Y6B6,Q15904,Q15800,P34913,P37268,Q9BV10,Q14739,Q9UBM7,Q9NZJ7,P07602,P61916,Q9UJS0,Q8N511,Q15392 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 397,318,95,325,197,103,41,269,275,113,308,151,58,29 | 2909,2501,2771,571,1087,113,325,197,2898,1095,2358,899,2504,2571,308,1130,1016,758,985,41,29,2280,95,318,58,860,915,103,395,275,269,151,397 | -1.099924828090018,-0.6137324247371202,-0.8402469607675234,0.5017859632503069,0.05907835699925959,2.2493125713395874,0.9687059891173524,1.5505926056196673,-1.0758316877354026,0.05907835699925959,-0.5254772864924734,0.1970700191478118,-0.6137324247371202,-0.6583511285219581,1.0205517659257686,0.039118345533642226,0.11858418117435018,0.31302577253021713,0.13829633186814977,3.162609148347032,3.4405377784263176,-0.48182900048661537,2.392786822066208,0.9860318695770233,2.834398419466517,0.23595476382188807,0.1970700191478118,2.3500331786247033,0.7929611203043013,1.1569131412555997,1.1737693798534528,1.8626921049716938,0.7929611203043013 | 3,053 |
Metabolism of steroids | 15 | 43 | 2.835073 | 0.004582 | Q15800,O95772,Q9BWD1,P37268,P49327,Q14739,P38435,Q9UBM7,Q9H2C2,Q14534,P04062,Q53GQ0,Q16850,Q15392,Q14849 | Processes and pathways | Reactome Pathways | msigdb_reactome | 95,68,5,197,229,41,107,269,192,183,56,283,60,29,30 | 2997,999,923,2881,68,56,1259,1828,1832,2078,2533,197,107,326,229,1099,1841,852,2277,2920,3031,2574,183,41,30,2372,1914,29,517,1629,2280,95,60,283,1348,590,1284,2107,5,1652,192,269,397 | -1.657669459103611,0.11858418117435018,0.17753878759272398,-1.0279450311062537,2.685462544005469,2.861170882369116,-0.04135865661767714,-0.28919332161258265,-0.28919332161258265,-0.3954626277985668,-0.6360002154493802,1.5505926056196673,2.307033723210691,0.9687059891173524,1.3565272843725606,0.05907835699925959,-0.28919332161258265,0.23595476382188807,-0.48182900048661537,-1.1241192412166017,-2.493024635127748,-0.6583511285219581,1.645661682349741,3.162609148347032,3.428112577652922,-0.5254772864924734,-0.31030054118727124,3.4405377784263176,0.5757898109834075,-0.20547903817502652,-0.48182900048661537,2.392786822066208,2.794064797575269,1.123076264470747,-0.08198652438815046,0.4831539193642934,-0.04135865661767714,-0.3954626277985668,4.466159447011184,-0.20547903817502652,1.6141131009311325,1.1737693798534528,0.7929611203043013 | 3,053 |
Golgi associated vesicle | 7 | 35 | 2.810947 | 0.00494 | P24390,Q9Y3B3,O43731,Q15363,Q8TCT8,Q8IUH4,Q8N511 | Localization | GO Cellular component | msigdb_gocc | 1,69,7,139,143,184,58 | 871,778,7,1667,2983,847,629,1559,1508,875,1,829,1373,544,1374,2476,1898,1901,1377,1792,1130,757,139,184,58,143,2288,1355,2058,635,1077,2338,239,69,1933 | 0.21654186145358403,0.29384424374464585,4.366865380443215,-0.2263016271137345,-1.4741094280213356,0.23595476382188807,0.4269371803541035,-0.18472611797839597,-0.16404228682087726,0.21654186145358403,5.242039873099177,0.255309170150584,-0.10239964490688236,0.5388920140603658,-0.10239964490688236,-0.5915469880276591,-0.31030054118727124,-0.31030054118727124,-0.10239964490688236,-0.2681581692824456,0.039118345533642226,0.31302577253021713,1.9688079417064501,1.645661682349741,2.834398419466517,1.9537430602483536,-0.48182900048661537,-0.08198652438815046,-0.37406084951540725,0.4269371803541035,0.07897567452569614,-0.5036138048570713,1.3071593288497105,2.685462544005469,-0.31030054118727124 | 3,053 |
Serine hydrolase activity | 7 | 17 | 2.80929 | 0.004965 | Q9H3G5,Q5JRX3,P42785,P67812,Q9HB40,P10619,Q16740 | Functions | GO Molecular function | msigdb_gomf | 66,164,46,207,53,185,190 | 624,872,2220,185,1887,2600,1680,46,1839,2087,1127,207,190,246,164,66,53 | 0.4269371803541035,0.21654186145358403,-0.4601221695313692,1.6299048673842986,-0.31030054118727124,-0.6807859438462549,-0.2263016271137345,3.0850861706306985,-0.28919332161258265,-0.3954626277985668,0.039118345533642226,1.486497014997707,1.6141131009311325,1.2574385968521233,1.7704807226942911,2.7263687739230678,3.006789555372895 | 3,053 |
Carbohydrate derivative transport | 12 | 18 | 2.809028 | 0.004969 | P12235,Q8TB61,P41440,Q08722,Q9NZJ7,P07602,Q9HC21,P61916,Q8WTV0,O00400,P05141,P12236 | Processes and pathways | GO Biological process | msigdb_gobp | 257,39,362,367,275,113,339,308,26,154,377,188 | 412,154,690,377,113,257,188,362,308,618,367,2874,534,39,26,1023,339,275 | 0.7393289521585672,1.8167337774526302,0.3702313895262678,0.8107434624970358,2.2493125713395874,1.2073587193318431,1.6141131009311325,0.8638097235543348,1.0205517659257686,0.4457299111164649,0.846167456483267,-1.0041494608343033,0.5573667616763491,3.1882814967797093,3.588162517641911,0.11858418117435018,0.9339209551785153,1.1569131412555997 | 3,053 |
Oxidative phosphorylation | 17 | 60 | 2.803722 | 0.005052 | O75964,O75306,P22695,Q7KZN9,O75489,P03886,P20674,P13073,O14949,P03915,O43676,P24539,P14406,Q9BSK2,Q9UDW1,O75438,Q9H3K2 | Processes and pathways | GO Biological process | msigdb_gobp | 35,195,324,43,384,45,421,330,142,304,47,238,85,86,92,126,127 | 952,142,47,1177,195,2350,126,384,977,35,434,628,1604,978,595,691,45,304,1558,1731,614,1781,1507,330,85,2224,1298,1889,1831,421,324,238,2656,1260,3014,2438,2134,828,670,1222,1303,2776,2183,783,2569,830,1063,960,757,2413,650,1760,43,2847,86,2671,127,92,796,1053 | 0.15794771197129795,1.9537430602483536,3.072090978975674,-0.0009917498407377972,1.566526139717696,-0.5254772864924734,2.1618805177312446,0.7929611203043013,0.13829633186814977,3.2266342617272703,0.7033333538782307,0.4269371803541035,-0.20547903817502652,0.13829633186814977,0.464468695655408,0.3702313895262678,3.0850861706306985,1.0377463366595439,-0.18472611797839597,-0.24719447231895844,0.4457299111164649,-0.2681581692824456,-0.16404228682087726,0.9513357791761082,2.5056210267947026,-0.4601221695313692,-0.061639706843019025,-0.31030054118727124,-0.28919332161258265,0.7213554512800274,0.9687059891173524,1.3071593288497105,-0.7259104599277266,-0.04135865661767714,-1.959204894557855,-0.5694431482641074,-0.4169396623740783,0.255309170150584,0.3891883162351104,-0.021142844948492293,-0.061639706843019025,-0.8402469607675234,-0.4384926181619229,0.29384424374464585,-0.6583511285219581,0.255309170150584,0.07897567452569614,0.15794771197129795,0.31302577253021713,-0.5474201594629304,0.40809011351908236,-0.24719447231895844,3.149741568733179,-0.9568488266934512,2.5056210267947026,-0.7259104599277266,2.1325052522465455,2.4352981359162196,0.29384424374464585,0.09881078799017154 | 3,053 |
Sphingolipid metabolism in senescence | 6 | 11 | 2.795174 | 0.005187 | P16278,Q06136,Q16739,Q13510,Q96G23,P04062 | Processes and pathways | WikiPathways | msigdb_wp | 65,102,136,40,11,56 | 295,56,1003,65,1609,1736,631,102,40,136,11 | 1.0720060894912629,2.861170882369116,0.11858418117435018,2.739955797601633,-0.20547903817502652,-0.24719447231895844,0.4269371803541035,2.3500331786247033,3.162609148347032,1.998844642307609,4.266395697843969 | 3,053 |
Alcohol biosynthetic process | 12 | 33 | 2.793548 | 0.005213 | Q15800,P16435,P37268,O15269,Q13510,Q14739,Q9UBM7,P00374,Q9H2C2,P04062,Q16850,Q15392 | Processes and pathways | GO Biological process | msigdb_gobp | 95,323,197,295,40,41,269,84,192,56,60,29 | 2852,295,1451,2175,84,1826,56,571,2752,1297,1259,323,2261,1567,197,2267,326,1743,696,2920,40,2574,41,1914,29,2280,95,447,60,2847,192,1319,269 | -0.9804510545643588,1.0720060894912629,-0.14342697267853247,-0.4384926181619229,2.519607315435531,-0.28919332161258265,2.861170882369116,0.5017859632503069,-0.8172019719548473,-0.061639706843019025,-0.04135865661767714,0.9687059891173524,-0.48182900048661537,-0.18472611797839597,1.5505926056196673,-0.48182900048661537,0.9687059891173524,-0.24719447231895844,0.3702313895262678,-1.1241192412166017,3.162609148347032,-0.6583511285219581,3.162609148347032,-0.31030054118727124,3.4405377784263176,-0.48182900048661537,2.392786822066208,0.6852623302074585,2.794064797575269,-0.9568488266934512,1.6141131009311325,-0.061639706843019025,1.1737693798534528 | 3,053 |
Cholesterol binding | 7 | 12 | 2.784429 | 0.005362 | P21796,O95772,P35610,P45880,O15118,Q14108,Q14849 | Functions | GO Molecular function | msigdb_gomf | 2,68,258,15,51,20,30 | 51,2175,68,2353,2,2078,258,15,308,20,30,705 | 3.0329755799706857,-0.4384926181619229,2.685462544005469,-0.5254772864924734,4.914940523522634,-0.3954626277985668,1.2073587193318431,4.096236762872413,1.0205517659257686,3.863819674290911,3.428112577652922,0.3702313895262678 | 3,053 |
Cellular ion homeostasis | 33 | 88 | 2.776919 | 0.005488 | Q9P0T7,O76024,P05023,Q14964,O95202,Q92544,P09601,Q9Y487,P50897,O75503,Q96PU5,Q7L0J3,Q96TC7,Q14344,Q8NEW0,P04920,Q96A33,O60826,O43819,P16615,Q8N511,Q15904,Q8NE86,P54709,Q9HC07,O75787,P0CG08,P20020,Q9HD20,Q9Y6M7,P62942,P0DP25,Q93050 | Processes and pathways | GO Biological process | msigdb_gobp | 396,256,264,388,148,538,22,156,27,158,286,166,428,564,49,305,306,558,556,436,58,318,452,577,196,446,572,331,211,487,98,361,121 | 2345,1214,556,2749,558,1369,158,446,627,2623,256,148,1993,1606,305,264,847,1731,1055,2598,2433,2353,1506,22,572,361,2529,1997,1459,436,2312,331,2076,2079,826,2702,1736,1999,2472,1095,27,1098,674,927,1375,577,1010,1470,1344,98,1129,588,757,2365,564,388,1389,1695,318,886,2284,166,1435,1110,58,452,49,538,1704,121,306,861,1437,286,428,1494,2671,1118,196,211,396,708,2209,796,1546,156,1409,487 | -0.5254772864924734,-0.021142844948492293,0.5203652040028177,-0.8172019719548473,0.5203652040028177,-0.10239964490688236,1.8013490730391473,0.6852623302074585,0.4269371803541035,-0.7033054530869399,1.2073587193318431,1.893169553532986,-0.35273367187282356,-0.20547903817502652,1.0377463366595439,1.1905844892407613,0.23595476382188807,-0.24719447231895844,0.07897567452569614,-0.6807859438462549,-0.5694431482641074,-0.5254772864924734,-0.16404228682087726,3.828386645902461,0.5017859632503069,0.8638097235543348,-0.6360002154493802,-0.35273367187282356,-0.14342697267853247,0.7033333538782307,-0.5036138048570713,0.9513357791761082,-0.3954626277985668,-0.3954626277985668,0.255309170150584,-0.7713802427604488,-0.24719447231895844,-0.35273367187282356,-0.5915469880276591,0.05907835699925959,3.5515088405121995,0.05907835699925959,0.3891883162351104,0.17753878759272398,-0.10239964490688236,0.5017859632503069,0.11858418117435018,-0.14342697267853247,-0.08198652438815046,2.378562703431359,0.039118345533642226,0.4831539193642934,0.31302577253021713,-0.5254772864924734,0.5203652040028177,0.7929611203043013,-0.10239964490688236,-0.2263016271137345,0.9860318695770233,0.21654186145358403,-0.48182900048661537,1.7394792650550464,-0.12287961106727112,0.05907835699925959,2.834398419466517,0.6852623302074585,3.072090978975674,0.5573667616763491,-0.2263016271137345,2.1911393985906495,1.0377463366595439,0.23595476382188807,-0.12287961106727112,1.1060951140545585,0.7213554512800274,-0.14342697267853247,-0.7259104599277266,0.05907835699925959,1.566526139717696,1.4703817232301912,0.7929611203043013,0.3702313895262678,-0.4384926181619229,0.29384424374464585,-0.16404228682087726,1.8167337774526302,-0.10239964490688236,0.6307523498834328 | 3,053 |
Nucleobase containing compound transmembrane transporter activity | 11 | 14 | 2.770582 | 0.005596 | L0R6Q1,P12235,Q8TB61,Q9H2D1,P41440,Q9HC21,Q9BSK2,Q6NUK1,O00400,P05141,P12236 | Functions | GO Molecular function | msigdb_gomf | 412,257,39,109,362,339,86,534,154,377,188 | 412,154,690,377,257,188,362,545,534,39,1023,86,109,339 | 0.7393289521585672,1.8167337774526302,0.3702313895262678,0.8107434624970358,1.2073587193318431,1.6141131009311325,0.8638097235543348,0.5388920140603658,0.5573667616763491,3.1882814967797093,0.11858418117435018,2.5056210267947026,2.2926453330472487,0.9339209551785153 | 3,053 |
Increased bone mineral density | 6 | 24 | 2.770127 | 0.005603 | P54802,Q14739,Q13126,Q14108,P04062,Q15392 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 161,41,79,20,56,29 | 2771,56,825,1090,2815,1675,2601,672,1152,161,2569,2537,1904,79,833,20,41,1389,1428,29,1585,1769,2019,228 | -0.8402469607675234,2.861170882369116,0.255309170150584,0.05907835699925959,-0.9099290428795153,-0.2263016271137345,-0.6807859438462549,0.3891883162351104,0.019095144049973707,1.7859314470019894,-0.6583511285219581,-0.6360002154493802,-0.31030054118727124,2.575295500784994,0.255309170150584,3.863819674290911,3.162609148347032,-0.10239964490688236,-0.12287961106727112,3.4405377784263176,-0.18472611797839597,-0.24719447231895844,-0.35273367187282356,1.372905949710868 | 3,053 |
Respiratory chain | 13 | 31 | 2.750161 | 0.005957 | O75306,P22695,Q9P0J0,O75489,Q6DKK2,P03886,Q86Y39,O14949,P03915,O43676,Q96CU9,Q9UDW1,O75438 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 195,324,203,384,140,45,204,142,304,47,281,92,126 | 952,142,47,1177,195,126,384,434,628,1604,978,595,691,45,304,614,1298,1831,324,3014,828,2183,783,2413,650,140,204,281,203,92,1053 | 0.15794771197129795,1.9537430602483536,3.072090978975674,-0.0009917498407377972,1.566526139717696,2.1618805177312446,0.7929611203043013,0.7033333538782307,0.4269371803541035,-0.20547903817502652,0.13829633186814977,0.464468695655408,0.3702313895262678,3.0850861706306985,1.0377463366595439,0.4457299111164649,-0.061639706843019025,-0.28919332161258265,0.9687059891173524,-1.959204894557855,0.255309170150584,-0.4384926181619229,0.29384424374464585,-0.5474201594629304,0.40809011351908236,1.9688079417064501,1.502575541135129,1.1400155210794878,1.5186175105719402,2.4352981359162196,0.09881078799017154 | 3,053 |
Cholesterol metabolism | 10 | 24 | 2.749416 | 0.00597 | Q15800,P35610,P37268,Q14739,Q9UBM7,O15118,Q9H2C2,P04062,Q16850,Q15392 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 95,258,197,41,269,51,192,56,60,29 | 51,2175,1826,2501,56,571,1259,2533,258,197,308,618,2680,2920,2574,41,1914,29,2280,95,60,192,269,2648 | 3.0329755799706857,-0.4384926181619229,-0.28919332161258265,-0.6137324247371202,2.861170882369116,0.5017859632503069,-0.04135865661767714,-0.6360002154493802,1.2073587193318431,1.5505926056196673,1.0205517659257686,0.4457299111164649,-0.7486017803237077,-1.1241192412166017,-0.6583511285219581,3.162609148347032,-0.31030054118727124,3.4405377784263176,-0.48182900048661537,2.392786822066208,2.794064797575269,1.6141131009311325,1.1737693798534528,-0.7033054530869399 | 3,053 |
Sterol metabolism | 10 | 24 | 2.749416 | 0.00597 | Q15800,P35610,P37268,Q14739,Q9UBM7,O15118,Q9H2C2,P04062,Q16850,Q15392 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 95,258,197,41,269,51,192,56,60,29 | 51,2175,1826,2501,56,571,1259,2533,258,197,308,618,2680,2920,2574,41,1914,29,2280,95,60,192,269,2648 | 3.0329755799706857,-0.4384926181619229,-0.28919332161258265,-0.6137324247371202,2.861170882369116,0.5017859632503069,-0.04135865661767714,-0.6360002154493802,1.2073587193318431,1.5505926056196673,1.0205517659257686,0.4457299111164649,-0.7486017803237077,-1.1241192412166017,-0.6583511285219581,3.162609148347032,-0.31030054118727124,3.4405377784263176,-0.48182900048661537,2.392786822066208,2.794064797575269,1.6141131009311325,1.1737693798534528,-0.7033054530869399 | 3,053 |
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