term stringlengths 2 121 | overlap int64 6 281 | setsize int64 7 499 | score float64 1.96 10.6 | pval float64 0 0.05 | edge stringlengths 41 1.97k | type stringclasses 5 values | subtype stringclasses 24 values | subtype_key stringclasses 24 values | edge_idxs stringlengths 11 1.17k | ann_idxs stringlengths 19 2.31k | ann_vals stringlengths 124 9.94k | sig_size int64 2.2k 3.73k |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sphingolipid metabolism integrated pathway | 7 | 9 | 2.742393 | 0.006099 | Q06136,Q16739,Q8TCT0,Q13510,Q96G23,O95470,P27544 | Processes and pathways | WikiPathways | msigdb_wp | 102,136,169,40,11,61,159 | 295,1451,61,159,102,40,136,169,11 | 1.0720060894912629,-0.14342697267853247,2.780573201657302,1.7859314470019894,2.3500331786247033,3.162609148347032,1.998844642307609,1.7239281707505134,4.266395697843969 | 3,053 |
Sphingolipid metabolism overview | 7 | 9 | 2.742393 | 0.006099 | Q06136,Q16739,Q8TCT0,Q13510,Q96G23,O95470,P27544 | Processes and pathways | WikiPathways | msigdb_wp | 102,136,169,40,11,61,159 | 295,1451,61,159,102,40,136,169,11 | 1.0720060894912629,-0.14342697267853247,2.780573201657302,1.7859314470019894,2.3500331786247033,3.162609148347032,1.998844642307609,1.7239281707505134,4.266395697843969 | 3,053 |
Endopeptidase activity | 21 | 67 | 2.736692 | 0.006206 | Q99797,Q9NZ08,Q9BXS4,Q8TCT8,Q96RU2,Q92542,Q96K76,Q5JRX3,P60900,Q8TCT9,P20618,P49721,Q16740,P22695,O75844,P28072,P67812,P42892,P07858,Q14674,Q4J6C6 | Functions | GO Molecular function | msigdb_gomf | 392,137,267,143,144,408,418,164,172,179,177,55,190,324,72,76,207,212,223,356,246 | 624,2594,729,872,1879,2128,72,1145,1505,223,1887,2074,2974,177,324,2133,924,76,669,2600,2808,1680,2083,1466,2629,212,2230,1839,755,55,958,1061,1127,1568,172,207,677,1269,2899,356,2759,190,246,164,760,2240,143,179,2998,408,944,567,1645,2105,418,144,568,1396,2107,392,2585,267,429,137,1079,709,1409 | 0.4269371803541035,-0.6807859438462549,0.3321505284860475,0.21654186145358403,-0.31030054118727124,-0.4169396623740783,2.658069675513038,0.019095144049973707,-0.16404228682087726,1.3892463318502195,-0.31030054118727124,-0.3954626277985668,-1.397261622755791,1.661383738534994,0.9687059891173524,-0.4169396623740783,0.17753878759272398,2.6029870534417396,0.3891883162351104,-0.6807859438462549,-0.8866095938314523,-0.2263016271137345,-0.3954626277985668,-0.14342697267853247,-0.7033054530869399,1.4542294549861097,-0.4601221695313692,-0.28919332161258265,0.31302577253021713,2.927699712335164,0.15794771197129795,0.07897567452569614,0.039118345533642226,-0.18472611797839597,1.6770712269532793,1.486497014997707,0.3891883162351104,-0.04135865661767714,-1.0758316877354026,0.881405908837468,-0.8172019719548473,1.6141131009311325,1.2574385968521233,1.7704807226942911,0.31302577253021713,-0.4601221695313692,1.9537430602483536,1.661383738534994,-1.657669459103611,0.7572541827182976,0.17753878759272398,0.5203652040028177,-0.20547903817502652,-0.3954626277985668,0.7393289521585672,1.9537430602483536,0.5203652040028177,-0.10239964490688236,-0.3954626277985668,0.7929611203043013,-0.6583511285219581,1.1905844892407613,0.7213554512800274,1.998844642307609,0.07897567452569614,0.3702313895262678,-0.10239964490688236 | 3,053 |
Lipoprotein metabolic process | 7 | 25 | 2.733549 | 0.006266 | Q16739,Q9H490,Q9NUJ1,P04062,P50897,Q8IUH4,Q9BQE5 | Processes and pathways | GO Biological process | msigdb_gobp | 136,106,111,56,27,184,63 | 729,1775,2700,2069,2501,56,571,1055,850,1895,27,2145,136,518,1347,184,1349,944,2823,2584,63,2159,106,111,224 | 0.3321505284860475,-0.2681581692824456,-0.7713802427604488,-0.3954626277985668,-0.6137324247371202,2.861170882369116,0.5017859632503069,0.07897567452569614,0.23595476382188807,-0.31030054118727124,3.5515088405121995,-0.4169396623740783,1.998844642307609,0.5757898109834075,-0.08198652438815046,1.645661682349741,-0.08198652438815046,0.17753878759272398,-0.9099290428795153,-0.6583511285219581,2.7670579060311247,-0.4169396623740783,2.3213944057139972,2.278229101219084,1.3892463318502195 | 3,053 |
Abnormal circulating lipid concentration | 22 | 71 | 2.727715 | 0.006377 | Q9Y6B6,Q9NVI7,Q9UBM7,Q9NZJ7,Q9UJS0,Q15392,P23786,Q14739,P61916,Q8N511,O95470,Q15904,P34913,P37268,O75844,Q16836,Q15800,Q9Y4P3,P06280,Q9BV10,P07602,O43772 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 397,395,269,275,151,29,284,41,308,58,61,318,325,197,72,352,95,228,231,103,113,241 | 1987,1452,241,488,2909,72,627,61,2501,2771,571,231,1087,113,1781,3023,284,924,1093,402,325,2601,1150,2883,197,2898,543,1951,1095,2358,926,899,2359,2504,1099,2408,2440,2571,308,2537,1130,1905,1016,758,985,41,1428,29,2280,95,318,352,479,2147,58,860,988,2823,2741,915,103,1050,395,275,269,1769,151,1174,228,1720,397 | -0.35273367187282356,-0.14342697267853247,1.2740517609654562,0.612482250975132,-1.099924828090018,2.658069675513038,0.4269371803541035,2.780573201657302,-0.6137324247371202,-0.8402469607675234,0.5017859632503069,1.3401101108679196,0.05907835699925959,2.2493125713395874,-0.2681581692824456,-2.2489695919255768,1.1060951140545585,0.17753878759272398,0.05907835699925959,0.7572541827182976,0.9687059891173524,-0.6807859438462549,0.019095144049973707,-1.0279450311062537,1.5505926056196673,-1.0758316877354026,0.5388920140603658,-0.3314804483105227,0.05907835699925959,-0.5254772864924734,0.17753878759272398,0.1970700191478118,-0.5254772864924734,-0.6137324247371202,0.05907835699925959,-0.5474201594629304,-0.5694431482641074,-0.6583511285219581,1.0205517659257686,-0.6360002154493802,0.039118345533642226,-0.31030054118727124,0.11858418117435018,0.31302577253021713,0.13829633186814977,3.162609148347032,-0.12287961106727112,3.4405377784263176,-0.48182900048661537,2.392786822066208,0.9860318695770233,0.8989563120030468,0.6307523498834328,-0.4169396623740783,2.834398419466517,0.23595476382188807,0.13829633186814977,-0.9099290428795153,-0.7942466885201216,0.1970700191478118,2.3500331786247033,0.09881078799017154,0.7929611203043013,1.1569131412555997,1.1737693798534528,-0.24719447231895844,1.8626921049716938,0.019095144049973707,1.372905949710868,-0.2263016271137345,0.7929611203043013 | 3,053 |
Lytic vacuole organization | 11 | 27 | 2.720834 | 0.006512 | Q9P0T7,P54802,Q9HC07,Q8NHS3,Q14964,P11117,Q14108,P04062,Q8N511,P50897,O75503 | Processes and pathways | GO Biological process | msigdb_gobp | 396,161,196,37,388,240,20,56,58,27,158 | 2345,624,158,446,56,2598,573,240,631,27,1098,161,1901,20,388,1483,58,37,861,994,1285,196,3027,396,1028,1324,2426 | -0.5254772864924734,0.4269371803541035,1.8013490730391473,0.6852623302074585,2.861170882369116,-0.6807859438462549,0.5017859632503069,1.2906252596776078,0.4269371803541035,3.5515088405121995,0.05907835699925959,1.7859314470019894,-0.31030054118727124,3.863819674290911,0.7929611203043013,-0.14342697267853247,2.834398419466517,3.2010864353849686,0.23595476382188807,0.13829633186814977,-0.04135865661767714,1.566526139717696,-2.369543483700357,0.7929611203043013,0.11858418117435018,-0.061639706843019025,-0.5474201594629304 | 3,053 |
Inorganic anion transmembrane transporter activity | 7 | 22 | 2.714214 | 0.006643 | P21796,Q9UBX3,Q9C0H2,Q4KMQ2,P45880,Q9Y277,Q9H813 | Functions | GO Molecular function | msigdb_gomf | 2,36,6,296,15,245,287 | 2023,625,305,572,2,15,927,1152,1010,531,1389,296,2859,2874,767,1244,6,287,814,36,245,487 | -0.37406084951540725,0.4269371803541035,1.0377463366595439,0.5017859632503069,4.914940523522634,4.096236762872413,0.17753878759272398,0.019095144049973707,0.11858418117435018,0.5573667616763491,-0.10239964490688236,1.0720060894912629,-0.9804510545643588,-1.0041494608343033,0.31302577253021713,-0.021142844948492293,4.433189930630274,1.1060951140545585,0.2746055190128614,3.213870662525028,1.2740517609654562,0.6307523498834328 | 3,053 |
Outer membrane | 23 | 80 | 2.711265 | 0.006703 | P21796,Q9NS69,Q9BUR5,Q9UBM7,Q9NZJ7,P45880,Q8IWA4,P09601,Q99720,O43169,O00264,Q13505,Q96TC7,Q9NVH1,Q8N4H5,Q8WY22,Q9UBF8,Q5XKP0,P52789,Q99623,Q9Y277,Q9Y512,Q9NZ45 | Localization | GO Cellular component | msigdb_gocc | 2,3,262,269,275,15,407,22,24,31,288,168,428,443,64,71,208,209,226,358,245,382,125 | 288,843,2997,31,528,749,2350,2909,1778,1454,613,1826,2597,823,22,2532,2,1785,2775,631,1467,15,899,226,2440,959,1378,2365,2366,168,2901,1105,2095,886,549,937,209,448,739,619,987,407,1197,1700,653,64,2992,1313,1804,860,71,1278,1536,428,657,358,24,2798,262,1137,967,2492,2849,1500,685,3,1980,443,2863,552,998,125,275,208,269,2424,245,2121,382,971 | 1.0890718099012444,0.23595476382188807,-1.657669459103611,3.4032042415630985,0.5573667616763491,0.31302577253021713,-0.5254772864924734,-1.099924828090018,-0.2681581692824456,-0.14342697267853247,0.4457299111164649,-0.28919332161258265,-0.6807859438462549,0.255309170150584,3.828386645902461,-0.6360002154493802,4.914940523522634,-0.2681581692824456,-0.8402469607675234,0.4269371803541035,-0.14342697267853247,4.096236762872413,0.1970700191478118,1.372905949710868,-0.5694431482641074,0.15794771197129795,-0.10239964490688236,-0.5254772864924734,-0.5254772864924734,1.7239281707505134,-1.0758316877354026,0.05907835699925959,-0.3954626277985668,0.21654186145358403,0.5388920140603658,0.17753878759272398,1.4703817232301912,0.6852623302074585,0.3321505284860475,0.4457299111164649,0.13829633186814977,0.7572541827182976,-0.0009917498407377972,-0.2263016271137345,0.40809011351908236,2.7535188063677927,-1.5782524526378907,-0.061639706843019025,-0.2681581692824456,0.23595476382188807,2.671778387447355,-0.04135865661767714,-0.16404228682087726,0.7213554512800274,0.40809011351908236,0.881405908837468,3.757058561044739,-0.8633825363003653,1.2073587193318431,0.039118345533642226,0.15794771197129795,-0.5915469880276591,-0.9568488266934512,-0.14342697267853247,0.3891883162351104,4.841737850614046,-0.3314804483105227,0.7033333538782307,-0.9804510545643588,0.5388920140603658,0.13829633186814977,2.1765244342071473,1.1569131412555997,1.486497014997707,1.1737693798534528,-0.5474201594629304,1.2740517609654562,-0.3954626277985668,0.8107434624970358,0.15794771197129795 | 3,053 |
Sterol biosynthetic process | 9 | 21 | 2.705769 | 0.006815 | Q15800,P16435,P37268,Q14739,Q9UBM7,Q9H2C2,Q14534,Q16850,Q15392 | Processes and pathways | GO Biological process | msigdb_gobp | 95,323,197,41,269,192,183,60,29 | 2175,1826,571,1297,1259,323,197,2267,326,1743,2920,2574,183,41,1914,29,2280,95,60,192,269 | -0.4384926181619229,-0.28919332161258265,0.5017859632503069,-0.061639706843019025,-0.04135865661767714,0.9687059891173524,1.5505926056196673,-0.48182900048661537,0.9687059891173524,-0.24719447231895844,-1.1241192412166017,-0.6583511285219581,1.645661682349741,3.162609148347032,-0.31030054118727124,3.4405377784263176,-0.48182900048661537,2.392786822066208,2.794064797575269,1.6141131009311325,1.1737693798534528 | 3,053 |
Abnormal biliary tract morphology | 7 | 24 | 2.697092 | 0.006995 | Q14739,Q92889,Q5XKP0,P07602,Q14108,P09601,P04062 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 41,202,209,113,20,22,56 | 2928,625,2771,56,113,22,598,1461,1680,2359,1099,677,1269,20,41,209,202,1645,591,1075,275,970,2907,1720 | -1.1484159978357622,0.4269371803541035,-0.8402469607675234,2.861170882369116,2.2493125713395874,3.828386645902461,0.464468695655408,-0.14342697267853247,-0.2263016271137345,-0.5254772864924734,0.05907835699925959,0.3891883162351104,-0.04135865661767714,3.863819674290911,3.162609148347032,1.4703817232301912,1.5186175105719402,-0.20547903817502652,0.4831539193642934,0.07897567452569614,1.1569131412555997,0.15794771197129795,-1.0758316877354026,-0.2263016271137345 | 3,053 |
Tclin | 27 | 85 | 2.689239 | 0.007162 | Q9BVA1,O43924,Q16739,P05023,P21964,P04350,O75489,Q99720,Q7L0J3,P03886,P03915,O43676,P20618,Q13885,P49721,O75306,Q9P0J0,P68371,Q86Y39,P00374,P07437,P62942,P06280,P38435,Q14145,P0DP25,O75438 | Drugs and Diseases | Pharos IDG Category | pharos_protein_category | 263,8,136,264,387,268,384,24,166,45,304,47,177,440,55,195,203,332,204,84,348,98,231,107,235,361,126 | 952,47,8,975,1177,195,126,384,434,628,1604,978,595,84,2222,2070,1557,45,304,268,264,2308,1940,231,348,2433,2465,2435,1996,361,573,1560,2354,1944,1003,2132,1259,1828,1831,177,2882,387,2916,2226,2562,1735,669,3014,1093,641,107,631,643,55,2183,756,2793,783,577,1010,98,332,1904,2539,931,1065,1475,440,235,2413,136,650,2510,166,204,1971,24,1023,1442,480,263,2522,203,2982,1053 | 0.15794771197129795,3.072090978975674,4.344641601575348,0.13829633186814977,-0.0009917498407377972,1.566526139717696,2.1618805177312446,0.7929611203043013,0.7033333538782307,0.4269371803541035,-0.20547903817502652,0.13829633186814977,0.464468695655408,2.519607315435531,-0.4601221695313692,-0.3954626277985668,-0.18472611797839597,3.0850861706306985,1.0377463366595439,1.1737693798534528,1.1905844892407613,-0.5036138048570713,-0.3314804483105227,1.3401101108679196,0.8989563120030468,-0.5694431482641074,-0.5915469880276591,-0.5694431482641074,-0.35273367187282356,0.8638097235543348,0.5017859632503069,-0.18472611797839597,-0.5254772864924734,-0.3314804483105227,0.11858418117435018,-0.4169396623740783,-0.04135865661767714,-0.28919332161258265,-0.28919332161258265,1.661383738534994,-1.0279450311062537,0.7929611203043013,-1.1241192412166017,-0.4601221695313692,-0.6583511285219581,-0.24719447231895844,0.3891883162351104,-1.959204894557855,0.05907835699925959,0.40809011351908236,2.307033723210691,0.4269371803541035,0.40809011351908236,2.927699712335164,-0.4384926181619229,0.31302577253021713,-0.8633825363003653,0.29384424374464585,0.5017859632503069,0.11858418117435018,2.378562703431359,0.9513357791761082,-0.31030054118727124,-0.6360002154493802,0.17753878759272398,0.07897567452569614,-0.14342697267853247,0.7033333538782307,1.3236542021070108,-0.5474201594629304,1.998844642307609,0.40809011351908236,-0.6137324247371202,1.7394792650550464,1.502575541135129,-0.3314804483105227,3.757058561044739,0.11858418117435018,-0.12287961106727112,0.6307523498834328,1.2073587193318431,-0.6137324247371202,1.5186175105719402,-1.4483758495299948,0.09881078799017154 | 3,053 |
Nucleotide transmembrane transporter activity | 8 | 12 | 2.685873 | 0.007234 | P12235,Q8TB61,P41440,Q9H2D1,Q9HC21,Q9BSK2,O00400,P12236 | Functions | GO Molecular function | msigdb_gomf | 257,39,362,109,339,86,154,188 | 154,690,377,257,188,362,534,39,1023,86,109,339 | 1.8167337774526302,0.3702313895262678,0.8107434624970358,1.2073587193318431,1.6141131009311325,0.8638097235543348,0.5573667616763491,3.1882814967797093,0.11858418117435018,2.5056210267947026,2.2926453330472487,0.9339209551785153 | 3,053 |
Organophosphate ester transmembrane transporter activity | 8 | 12 | 2.685873 | 0.007234 | P12235,Q8TB61,P41440,Q9H2D1,Q9HC21,Q9BSK2,O00400,P12236 | Functions | GO Molecular function | msigdb_gomf | 257,39,362,109,339,86,154,188 | 154,690,377,257,188,362,534,39,1023,86,109,339 | 1.8167337774526302,0.3702313895262678,0.8107434624970358,1.2073587193318431,1.6141131009311325,0.8638097235543348,0.5573667616763491,3.1882814967797093,0.11858418117435018,2.5056210267947026,2.2926453330472487,0.9339209551785153 | 3,053 |
Steroid biosynthetic process | 13 | 39 | 2.677032 | 0.007428 | Q15800,P16435,P37268,P05023,Q13510,Q14739,Q9UBM7,Q9H2C2,Q14534,Q53GQ0,Q16850,Q15392,Q14849 | Processes and pathways | GO Biological process | msigdb_gobp | 95,323,197,264,40,41,269,192,183,283,60,29,30 | 2175,1826,571,264,2465,1297,1259,1828,323,1832,2078,2533,694,197,2267,326,1743,2920,40,2574,183,41,30,1914,29,2708,1629,2280,95,60,283,590,2894,1284,2712,2492,192,269,1715 | -0.4384926181619229,-0.28919332161258265,0.5017859632503069,1.1905844892407613,-0.5915469880276591,-0.061639706843019025,-0.04135865661767714,-0.28919332161258265,0.9687059891173524,-0.28919332161258265,-0.3954626277985668,-0.6360002154493802,0.3702313895262678,1.5505926056196673,-0.48182900048661537,0.9687059891173524,-0.24719447231895844,-1.1241192412166017,3.162609148347032,-0.6583511285219581,1.645661682349741,3.162609148347032,3.428112577652922,-0.31030054118727124,3.4405377784263176,-0.7713802427604488,-0.20547903817502652,-0.48182900048661537,2.392786822066208,2.794064797575269,1.123076264470747,0.4831539193642934,-1.0518387672424332,-0.04135865661767714,-0.7713802427604488,-0.5915469880276591,1.6141131009311325,1.1737693798534528,-0.2263016271137345 | 3,053 |
Alcohol metabolic process | 22 | 83 | 2.671881 | 0.007543 | Q06520,P35610,P51648,Q9UBM7,Q8WTV0,Q15392,Q14849,O15269,Q13510,Q14739,O15118,P61916,Q14534,P04062,Q16850,Q9H2C2,Q9BQE5,P16435,P37268,P34913,P00374,Q15800 | Processes and pathways | GO Biological process | msigdb_gobp | 4,258,138,269,26,29,30,295,40,41,51,308,183,56,60,192,63,323,197,325,84,95 | 2852,51,295,1451,1723,1002,1775,663,2175,2770,84,1826,2501,56,571,847,2308,2752,1297,2436,1259,2178,1828,323,2261,2533,3005,325,1567,258,197,2267,599,326,643,2855,1126,2504,2505,138,1743,2477,696,308,618,2680,2409,2920,1130,4,677,40,2662,3012,2574,183,41,30,885,1914,29,2280,95,447,60,448,1488,582,2487,26,2847,2783,63,916,2862,192,1765,1319,1076,269,2648,869,815 | -0.9804510545643588,3.0329755799706857,1.0720060894912629,-0.14342697267853247,-0.24719447231895844,0.11858418117435018,-0.2681581692824456,0.3891883162351104,-0.4384926181619229,-0.8402469607675234,2.519607315435531,-0.28919332161258265,-0.6137324247371202,2.861170882369116,0.5017859632503069,0.23595476382188807,-0.5036138048570713,-0.8172019719548473,-0.061639706843019025,-0.5694431482641074,-0.04135865661767714,-0.4384926181619229,-0.28919332161258265,0.9687059891173524,-0.48182900048661537,-0.6360002154493802,-1.7653839394083957,0.9687059891173524,-0.18472611797839597,1.2073587193318431,1.5505926056196673,-0.48182900048661537,0.464468695655408,0.9687059891173524,0.40809011351908236,-0.9804510545643588,0.039118345533642226,-0.6137324247371202,-0.6137324247371202,1.9688079417064501,-0.24719447231895844,-0.5915469880276591,0.3702313895262678,1.0205517659257686,0.4457299111164649,-0.7486017803237077,-0.5474201594629304,-1.1241192412166017,0.039118345533642226,4.564311687934693,0.3891883162351104,3.162609148347032,-0.7259104599277266,-1.9310836841037424,-0.6583511285219581,1.645661682349741,3.162609148347032,3.428112577652922,0.21654186145358403,-0.31030054118727124,3.4405377784263176,-0.48182900048661537,2.392786822066208,0.6852623302074585,2.794064797575269,0.6852623302074585,-0.14342697267853247,0.5017859632503069,-0.5915469880276591,3.588162517641911,-0.9568488266934512,-0.8402469607675234,2.7670579060311247,0.1970700191478118,-0.9804510545643588,1.6141131009311325,-0.24719447231895844,-0.061639706843019025,0.07897567452569614,1.1737693798534528,-0.7033054530869399,0.23595476382188807,0.2746055190128614 | 3,053 |
Lipid localization | 25 | 77 | 2.663113 | 0.007742 | Q9H6V9,Q9Y6B6,Q9BUR5,P35610,Q16739,Q9NZJ7,Q14108,Q99720,Q8WTV0,P31751,Q14849,P23786,Q4KMQ2,O15118,P61916,Q14534,P04062,P17900,Q9H2C2,Q9BQE5,P08183,O15260,P07602,O43772,P35790 | Processes and pathways | GO Biological process | msigdb_gobp | 0,397,262,258,136,275,20,24,26,402,30,284,296,51,308,183,56,186,192,63,349,110,113,241,255 | 1030,2997,1250,51,110,241,690,2699,1725,923,1454,846,1556,2701,2501,56,2772,571,1055,2895,113,2598,1332,349,639,598,186,1832,2078,284,694,3017,402,1785,258,255,529,308,618,415,2680,2857,2539,2844,2442,20,183,30,136,296,1483,2686,1043,2981,26,2894,1284,24,63,2419,262,2059,705,1286,192,463,0,541,3027,275,2389,2648,840,796,2166,1364,397 | 0.09881078799017154,-1.657669459103611,-0.04135865661767714,3.0329755799706857,2.278229101219084,1.2740517609654562,0.3702313895262678,-0.7713802427604488,-0.24719447231895844,0.17753878759272398,-0.14342697267853247,0.23595476382188807,-0.18472611797839597,-0.7713802427604488,-0.6137324247371202,2.861170882369116,-0.8402469607675234,0.5017859632503069,0.07897567452569614,-1.0758316877354026,2.2493125713395874,-0.6807859438462549,-0.08198652438815046,0.8989563120030468,0.40809011351908236,0.464468695655408,1.6299048673842986,-0.28919332161258265,-0.3954626277985668,1.1060951140545585,0.3702313895262678,-2.13113769044908,0.7572541827182976,-0.2681581692824456,1.2073587193318431,1.2240923176202834,0.5573667616763491,1.0205517659257686,0.4457299111164649,0.7393289521585672,-0.7486017803237077,-0.9804510545643588,-0.6360002154493802,-0.9568488266934512,-0.5694431482641074,3.863819674290911,1.645661682349741,3.428112577652922,1.998844642307609,1.0720060894912629,-0.14342697267853247,-0.7486017803237077,0.09881078799017154,-1.4227603628550716,3.588162517641911,-1.0518387672424332,-0.04135865661767714,3.757058561044739,2.7670579060311247,-0.5474201594629304,1.2073587193318431,-0.37406084951540725,0.3702313895262678,-0.04135865661767714,1.6141131009311325,0.6671420469276572,5.909244161018679,0.5573667616763491,-2.369543483700357,1.1569131412555997,-0.5254772864924734,-0.7033054530869399,0.255309170150584,0.29384424374464585,-0.4169396623740783,-0.08198652438815046,0.7929611203043013 | 3,053 |
Bulbar signs | 7 | 13 | 2.657477 | 0.007873 | P03886,Q9NZJ7,P03915,P07602,P04062,Q99720,Q9Y263 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 45,275,304,113,56,24,355 | 625,45,304,56,2223,113,366,2268,1389,988,24,275,355 | 0.4269371803541035,3.0850861706306985,1.0377463366595439,2.861170882369116,-0.4601221695313692,2.2493125713395874,0.846167456483267,-0.48182900048661537,-0.10239964490688236,0.13829633186814977,3.757058561044739,1.1569131412555997,0.8989563120030468 | 3,053 |
Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins | 17 | 60 | 2.652417 | 0.007992 | Q16134,O75964,O75306,P22695,Q9P0J0,O75489,P03886,P20674,Q86Y39,O14949,P03915,O43676,P13073,P24539,Q15526,Q9UDW1,O75438 | Processes and pathways | Reactome Pathways | msigdb_reactome | 189,35,195,324,203,384,45,421,204,142,304,47,330,238,244,92,126 | 952,142,47,556,1177,195,126,384,627,977,35,434,628,1604,978,595,691,45,304,1731,614,1458,1507,330,2311,1298,1889,1831,421,782,324,238,2656,3014,2134,828,1222,2817,1467,2776,2183,783,830,1063,1907,244,189,2413,650,1637,204,1441,1650,1442,1050,771,2522,203,92,1053 | 0.15794771197129795,1.9537430602483536,3.072090978975674,0.5203652040028177,-0.0009917498407377972,1.566526139717696,2.1618805177312446,0.7929611203043013,0.4269371803541035,0.13829633186814977,3.2266342617272703,0.7033333538782307,0.4269371803541035,-0.20547903817502652,0.13829633186814977,0.464468695655408,0.3702313895262678,3.0850861706306985,1.0377463366595439,-0.24719447231895844,0.4457299111164649,-0.14342697267853247,-0.16404228682087726,0.9513357791761082,-0.5036138048570713,-0.061639706843019025,-0.31030054118727124,-0.28919332161258265,0.7213554512800274,0.29384424374464585,0.9687059891173524,1.3071593288497105,-0.7259104599277266,-1.959204894557855,-0.4169396623740783,0.255309170150584,-0.021142844948492293,-0.9099290428795153,-0.14342697267853247,-0.8402469607675234,-0.4384926181619229,0.29384424374464585,0.255309170150584,0.07897567452569614,-0.31030054118727124,1.2740517609654562,1.6141131009311325,-0.5474201594629304,0.40809011351908236,-0.20547903817502652,1.502575541135129,-0.12287961106727112,-0.20547903817502652,-0.12287961106727112,0.09881078799017154,0.31302577253021713,-0.6137324247371202,1.5186175105719402,2.4352981359162196,0.09881078799017154 | 3,053 |
serine protease | 6 | 16 | 2.649383 | 0.008064 | Q9H3G5,P42785,P67812,Q9HB40,P10619,Q16740 | Functions | Panther Protein class | panther_protein_class | 66,46,207,53,185,190 | 624,872,185,1943,1887,2600,1680,46,1839,207,190,246,1349,66,53,2495 | 0.4269371803541035,0.21654186145358403,1.6299048673842986,-0.3314804483105227,-0.31030054118727124,-0.6807859438462549,-0.2263016271137345,3.0850861706306985,-0.28919332161258265,1.486497014997707,1.6141131009311325,1.2574385968521233,-0.08198652438815046,2.7263687739230678,3.006789555372895,-0.5915469880276591 | 3,053 |
Oxidoreduction driven active transmembrane transporter activity | 12 | 30 | 2.643007 | 0.008217 | O75306,Q7KZN9,O75489,P03886,P20674,Q9P0J0,P03915,P13073,O43676,Q15526,Q9UDW1,O75438 | Functions | GO Molecular function | msigdb_gomf | 195,43,384,45,421,203,304,330,47,244,92,126 | 952,47,1177,195,126,384,434,628,1604,978,595,691,45,304,614,1507,330,1831,421,3014,828,2183,783,244,2413,650,43,203,92,1053 | 0.15794771197129795,3.072090978975674,-0.0009917498407377972,1.566526139717696,2.1618805177312446,0.7929611203043013,0.7033333538782307,0.4269371803541035,-0.20547903817502652,0.13829633186814977,0.464468695655408,0.3702313895262678,3.0850861706306985,1.0377463366595439,0.4457299111164649,-0.16404228682087726,0.9513357791761082,-0.28919332161258265,0.7213554512800274,-1.959204894557855,0.255309170150584,-0.4384926181619229,0.29384424374464585,1.2740517609654562,-0.5474201594629304,0.40809011351908236,3.149741568733179,1.5186175105719402,2.4352981359162196,0.09881078799017154 | 3,053 |
Hydrolase activity hydrolyzing o glycosyl compounds | 11 | 24 | 2.642932 | 0.008219 | P54802,P16278,Q99519,P04066,P06280,O60502,P06865,O00754,Q9NUJ1,P04062,P17900 | Functions | GO Molecular function | msigdb_gomf | 161,65,132,454,231,104,386,383,111,56,186 | 623,383,104,56,454,231,386,2598,596,573,65,186,1058,1150,161,1910,2371,1854,2416,132,462,111,2556,1718 | 0.4269371803541035,0.7929611203043013,2.3357275135328175,2.861170882369116,0.6671420469276572,1.3401101108679196,0.7929611203043013,-0.6807859438462549,0.464468695655408,0.5017859632503069,2.739955797601633,1.6299048673842986,0.07897567452569614,0.019095144049973707,1.7859314470019894,-0.31030054118727124,-0.5254772864924734,-0.28919332161258265,-0.5474201594629304,2.0585502205371826,0.6671420469276572,2.278229101219084,-0.6360002154493802,-0.2263016271137345 | 3,053 |
secondary carrier transporter | 6 | 16 | 2.631668 | 0.008497 | Q9UBX3,Q8TB61,O95202,Q9UJS0,Q96ES6,O00400 | Functions | Panther Protein class | panther_protein_class | 36,39,148,151,91,154 | 154,819,148,305,1010,531,1389,2686,39,1704,91,1244,793,36,151,487 | 1.8167337774526302,0.255309170150584,1.893169553532986,1.0377463366595439,0.11858418117435018,0.5573667616763491,-0.10239964490688236,-0.7486017803237077,3.1882814967797093,-0.2263016271137345,2.4352981359162196,-0.021142844948492293,0.29384424374464585,3.213870662525028,1.8626921049716938,0.6307523498834328 | 3,053 |
Hormone metabolic process | 10 | 30 | 2.625152 | 0.008661 | Q06520,P05023,O75844,Q9UBM7,P42892,Q9HB40,O95470,Q53GQ0,Q14849,P07858 | Processes and pathways | GO Biological process | msigdb_gobp | 4,264,72,269,212,53,61,283,30,223 | 1669,446,72,61,264,223,2465,2074,1828,323,1608,212,2937,1099,2844,4,30,1629,283,448,582,590,2487,1437,2712,53,1765,269,1983,815 | -0.2263016271137345,0.6852623302074585,2.658069675513038,2.780573201657302,1.1905844892407613,1.3892463318502195,-0.5915469880276591,-0.3954626277985668,-0.28919332161258265,0.9687059891173524,-0.20547903817502652,1.4542294549861097,-1.1728161868952576,0.05907835699925959,-0.9568488266934512,4.564311687934693,3.428112577652922,-0.20547903817502652,1.123076264470747,0.6852623302074585,0.5017859632503069,0.4831539193642934,-0.5915469880276591,-0.12287961106727112,-0.7713802427604488,3.006789555372895,-0.24719447231895844,1.1737693798534528,-0.3314804483105227,0.2746055190128614 | 3,053 |
Dementia | 17 | 60 | 2.620129 | 0.00879 | O76024,Q13510,Q92889,P04350,P03886,P35637,Q9NZJ7,P03915,Q9Y287,P07602,O15118,Q14108,P61916,P04062,P17900,Q9Y487,P27544 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 256,40,202,268,45,366,275,304,239,113,51,20,308,56,186,156,159 | 843,2397,51,872,625,528,1370,256,613,691,45,304,56,2130,268,847,386,113,1257,2773,186,1733,782,640,1735,159,2134,1677,366,456,2472,1095,2268,2505,2141,2569,308,2144,1620,698,833,40,20,1847,2375,1633,2992,1045,2201,202,1860,994,2847,685,275,892,3009,1324,239,156 | 0.23595476382188807,-0.5474201594629304,3.0329755799706857,0.21654186145358403,0.4269371803541035,0.5573667616763491,-0.10239964490688236,1.2073587193318431,0.4457299111164649,0.3702313895262678,3.0850861706306985,1.0377463366595439,2.861170882369116,-0.4169396623740783,1.1737693798534528,0.23595476382188807,0.7929611203043013,2.2493125713395874,-0.04135865661767714,-0.8402469607675234,1.6299048673842986,-0.24719447231895844,0.29384424374464585,0.40809011351908236,-0.24719447231895844,1.7859314470019894,-0.4169396623740783,-0.2263016271137345,0.846167456483267,0.6671420469276572,-0.5915469880276591,0.05907835699925959,-0.48182900048661537,-0.6137324247371202,-0.4169396623740783,-0.6583511285219581,1.0205517659257686,-0.4169396623740783,-0.20547903817502652,0.3702313895262678,0.255309170150584,3.162609148347032,3.863819674290911,-0.28919332161258265,-0.5254772864924734,-0.20547903817502652,-1.5782524526378907,0.09881078799017154,-0.4384926181619229,1.5186175105719402,-0.28919332161258265,0.13829633186814977,-0.9568488266934512,0.3891883162351104,1.1569131412555997,0.21654186145358403,-1.820052821881393,-0.061639706843019025,1.3071593288497105,1.8167337774526302 | 3,053 |
Mitochondrial protein import | 10 | 34 | 2.618511 | 0.008831 | Q8N4H5,P21796,Q9NS69,Q5JRX3,Q13505,O60830,O14925,Q99595,Q9UJS0,P12236 | Processes and pathways | Reactome Pathways | msigdb_reactome | 64,2,3,164,168,12,146,23,151,188 | 146,527,12,2787,2909,2128,819,1778,628,613,1731,614,2829,257,188,2,2656,2775,1126,677,168,1105,986,164,64,23,2783,2949,3,552,151,2907,382,2255 | 1.893169553532986,0.5573667616763491,4.210058257772574,-0.8633825363003653,-1.099924828090018,-0.4169396623740783,0.255309170150584,-0.2681581692824456,0.4269371803541035,0.4457299111164649,-0.24719447231895844,0.4457299111164649,-0.9333418075172426,1.2073587193318431,1.6141131009311325,4.914940523522634,-0.7259104599277266,-0.8402469607675234,0.039118345533642226,0.3891883162351104,1.7239281707505134,0.05907835699925959,0.13829633186814977,1.7704807226942911,2.7535188063677927,3.8165416179463243,-0.8402469607675234,-1.2219313118513195,4.841737850614046,0.5388920140603658,1.8626921049716938,-1.0758316877354026,0.8107434624970358,-0.4601221695313692 | 3,053 |
Nucleotide transport | 9 | 14 | 2.617458 | 0.008859 | P12235,Q8TB61,P41440,Q9H2D1,Q08722,Q9HC21,Q9BSK2,O00400,P12236 | Processes and pathways | GO Biological process | msigdb_gobp | 257,39,362,109,367,339,86,154,188 | 154,690,377,257,188,362,367,2874,534,39,1023,86,109,339 | 1.8167337774526302,0.3702313895262678,0.8107434624970358,1.2073587193318431,1.6141131009311325,0.8638097235543348,0.846167456483267,-1.0041494608343033,0.5573667616763491,3.1882814967797093,0.11858418117435018,2.5056210267947026,2.2926453330472487,0.9339209551785153 | 3,053 |
Regulation of blood pressure | 9 | 16 | 2.612547 | 0.008987 | Q9Y5X3,P05023,Q9NZ08,P20020,P42785,P42892,Q9HB40,P09601,Q9UIQ6 | Processes and pathways | GO Biological process | msigdb_gobp | 131,264,137,331,46,212,53,22,419 | 446,1938,264,22,2436,331,46,212,756,2505,960,564,53,137,419,131 | 0.6852623302074585,-0.3314804483105227,1.1905844892407613,3.828386645902461,-0.5694431482641074,0.9513357791761082,3.0850861706306985,1.4542294549861097,0.31302577253021713,-0.6137324247371202,0.15794771197129795,0.5203652040028177,3.006789555372895,1.998844642307609,0.7393289521585672,2.0882215813866165 | 3,053 |
Proton transmembrane transport | 15 | 45 | 2.601571 | 0.00928 | O75964,P12235,Q99623,P05023,Q7KZN9,P20674,P13073,P03915,Q9UDW1,P24539,Q15526,Q13423,Q96ES6,O00400,P05141 | Processes and pathways | GO Biological process | msigdb_gobp | 35,257,358,264,43,421,330,304,92,238,244,88,91,154,377 | 154,952,1452,1177,977,35,691,304,264,377,1731,614,1507,257,330,421,1462,2264,238,2656,2438,828,1222,456,2472,2776,927,830,1063,1470,648,757,88,244,43,1704,91,2847,358,1650,793,92,708,2209,796 | 1.8167337774526302,0.15794771197129795,-0.14342697267853247,-0.0009917498407377972,0.13829633186814977,3.2266342617272703,0.3702313895262678,1.0377463366595439,1.1905844892407613,0.8107434624970358,-0.24719447231895844,0.4457299111164649,-0.16404228682087726,1.2073587193318431,0.9513357791761082,0.7213554512800274,-0.14342697267853247,-0.48182900048661537,1.3071593288497105,-0.7259104599277266,-0.5694431482641074,0.255309170150584,-0.021142844948492293,0.6671420469276572,-0.5915469880276591,-0.8402469607675234,0.17753878759272398,0.255309170150584,0.07897567452569614,-0.14342697267853247,0.40809011351908236,0.31302577253021713,2.4916088032578028,1.2740517609654562,3.149741568733179,-0.2263016271137345,2.4352981359162196,-0.9568488266934512,0.881405908837468,-0.20547903817502652,0.29384424374464585,2.4352981359162196,0.3702313895262678,-0.4384926181619229,0.29384424374464585 | 3,053 |
Rhizomelia | 6 | 12 | 2.593816 | 0.009492 | Q9BV10,Q14739,Q9UBM7,O75718,O00116,Q15392 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 103,41,269,180,119,29 | 119,1822,2431,180,631,1373,1522,41,29,354,103,269 | 2.1911393985906495,-0.28919332161258265,-0.5694431482641074,1.645661682349741,0.4269371803541035,-0.10239964490688236,-0.16404228682087726,3.162609148347032,3.4405377784263176,0.8989563120030468,2.3500331786247033,1.1737693798534528 | 3,053 |
Organic anion transport | 23 | 44 | 2.591553 | 0.009554 | P12235,Q9NZJ7,O75915,P53985,Q6NUK1,Q9UJS0,O00400,Q9UBX3,Q8TB61,Q7L0J3,O60831,P04920,P12236,Q9HC21,Q9Y6M7,P30825,Q9Y619,Q96QD8,P41440,Q9H2D1,Q08722,P07602,P05141 | Processes and pathways | GO Biological process | msigdb_gobp | 257,275,271,403,534,151,154,36,39,166,420,305,188,339,487,214,365,498,362,109,367,113,377 | 154,690,420,819,271,2772,305,377,1940,113,1125,639,257,188,598,3042,694,214,362,1101,403,1010,2277,531,367,2145,1630,2874,534,2686,166,39,890,498,1023,109,793,727,339,275,36,151,365,487 | 1.8167337774526302,0.3702313895262678,0.7213554512800274,0.255309170150584,1.1569131412555997,-0.8402469607675234,1.0377463366595439,0.8107434624970358,-0.3314804483105227,2.2493125713395874,0.039118345533642226,0.40809011351908236,1.2073587193318431,1.6141131009311325,0.464468695655408,-3.2311544845550535,0.3702313895262678,1.4380399974777385,0.8638097235543348,0.05907835699925959,0.7572541827182976,0.11858418117435018,-0.48182900048661537,0.5573667616763491,0.846167456483267,-0.4169396623740783,-0.20547903817502652,-1.0041494608343033,0.5573667616763491,-0.7486017803237077,1.7394792650550464,3.1882814967797093,0.21654186145358403,0.612482250975132,0.11858418117435018,2.2926453330472487,0.29384424374464585,0.3512189297429039,0.9339209551785153,1.1569131412555997,3.213870662525028,1.8626921049716938,0.8638097235543348,0.6307523498834328 | 3,053 |
Nadh dehydrogenase complex assembly | 11 | 26 | 2.591552 | 0.009554 | O75306,Q15070,Q9P0J0,O75489,P03886,Q86Y39,P03915,Q9H061,O43676,Q96CU9,O75438 | Processes and pathways | GO Biological process | msigdb_gobp | 195,134,203,384,45,204,304,50,47,281,126 | 47,1177,195,126,384,434,628,978,595,45,304,3014,783,134,2413,650,1637,204,281,1442,50,1050,2522,203,2907,1053 | 3.072090978975674,-0.0009917498407377972,1.566526139717696,2.1618805177312446,0.7929611203043013,0.7033333538782307,0.4269371803541035,0.13829633186814977,0.464468695655408,3.0850861706306985,1.0377463366595439,-1.959204894557855,0.29384424374464585,2.0138167795559077,-0.5474201594629304,0.40809011351908236,-0.20547903817502652,1.502575541135129,1.1400155210794878,-0.12287961106727112,3.072090978975674,0.09881078799017154,-0.6137324247371202,1.5186175105719402,-1.0758316877354026,0.09881078799017154 | 3,053 |
Receptor | 9 | 30 | 2.591484 | 0.009556 | P39210,Q9BUN8,P20645,Q567V2,A6NIH7,Q14108,Q8WTV0,Q9NRX5,Q9UQB8 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 105,170,282,48,18,20,26,124,97 | 18,1663,1667,488,446,1729,2983,1940,1508,299,282,105,2564,959,1383,1909,20,2820,48,2284,26,1532,1705,170,523,2972,124,2864,1362,97 | 4.004049716178841,-0.2263016271137345,-0.2263016271137345,0.612482250975132,0.6852623302074585,-0.24719447231895844,-1.4741094280213356,-0.3314804483105227,-0.16404228682087726,1.0548976876796043,1.123076264470747,2.3213944057139972,-0.6583511285219581,0.15794771197129795,-0.10239964490688236,-0.31030054118727124,3.863819674290911,-0.9099290428795153,3.072090978975674,-0.48182900048661537,3.588162517641911,-0.16404228682087726,-0.2263016271137345,1.7239281707505134,0.5757898109834075,-1.37187830834249,2.1765244342071473,-0.9804510545643588,-0.08198652438815046,2.392786822066208 | 3,053 |
Antiporter activity | 6 | 12 | 2.57093 | 0.010143 | Q9UBX3,P12235,P41440,P04920,O95202,P12236 | Functions | GO Molecular function | msigdb_gomf | 36,257,362,305,148,188 | 148,305,377,1125,257,188,362,927,1152,531,1704,36 | 1.893169553532986,1.0377463366595439,0.8107434624970358,0.039118345533642226,1.2073587193318431,1.6141131009311325,0.8638097235543348,0.17753878759272398,0.019095144049973707,0.5573667616763491,-0.2263016271137345,3.213870662525028 | 3,053 |
Membrane lipid catabolic process | 6 | 14 | 2.567889 | 0.010232 | Q99519,Q13510,P04062,P17900,P50897,O95470 | Processes and pathways | GO Biological process | msigdb_gobp | 132,40,56,186,27,61 | 61,56,454,231,386,2598,186,27,2539,40,2200,132,862,998 | 2.780573201657302,2.861170882369116,0.6671420469276572,1.3401101108679196,0.7929611203043013,-0.6807859438462549,1.6299048673842986,3.5515088405121995,-0.6360002154493802,3.162609148347032,-0.4384926181619229,2.0585502205371826,0.23595476382188807,0.13829633186814977 | 3,053 |
Glycosphingolipid metabolic process | 7 | 12 | 2.566804 | 0.010264 | Q99805,P16278,Q99519,Q16739,Q8TCT0,P04062,P17900 | Processes and pathways | GO Biological process | msigdb_gobp | 128,65,132,136,169,56,186 | 56,231,386,2598,65,186,2539,2365,136,169,132,128 | 2.861170882369116,1.3401101108679196,0.7929611203043013,-0.6807859438462549,2.739955797601633,1.6299048673842986,-0.6360002154493802,-0.5254772864924734,1.998844642307609,1.7239281707505134,2.0585502205371826,2.1177736122329143 | 3,053 |
Ph reduction | 7 | 13 | 2.556642 | 0.010569 | Q9P0T7,Q14964,Q9Y487,Q93050,Q8N511,P50897,O75503 | Processes and pathways | GO Biological process | msigdb_gobp | 396,388,156,121,58,27,158 | 158,446,572,27,1098,927,1470,388,58,121,396,2209,156 | 1.8013490730391473,0.6852623302074585,0.5017859632503069,3.5515088405121995,0.05907835699925959,0.17753878759272398,-0.14342697267853247,0.7929611203043013,2.834398419466517,2.1911393985906495,0.7929611203043013,-0.4384926181619229,1.8167337774526302 | 3,053 |
Mitochondrial membrane organization | 19 | 43 | 2.545687 | 0.010906 | Q9NS69,Q9BUR5,Q15070,P12235,P45880,Q8IWA4,O95202,O60313,Q9NX63,Q13505,Q9NVH1,Q9P0J0,Q5XKP0,P52789,P0DP25,Q9Y512,O14737,P05141,Q9H3K2 | Processes and pathways | GO Biological process | msigdb_gobp | 3,262,134,257,15,407,148,528,552,168,443,203,209,226,361,382,252,377,127 | 2345,252,528,2909,1778,148,2352,377,981,823,361,257,2438,850,2265,2775,2267,15,756,2359,226,2365,168,134,886,986,549,209,739,407,1197,1700,262,127,3,443,552,203,747,2907,1409,382,2255 | -0.5254772864924734,1.2240923176202834,0.5573667616763491,-1.099924828090018,-0.2681581692824456,1.893169553532986,-0.5254772864924734,0.8107434624970358,0.13829633186814977,0.255309170150584,0.8638097235543348,1.2073587193318431,-0.5694431482641074,0.23595476382188807,-0.48182900048661537,-0.8402469607675234,-0.48182900048661537,4.096236762872413,0.31302577253021713,-0.5254772864924734,1.372905949710868,-0.5254772864924734,1.7239281707505134,2.0138167795559077,0.21654186145358403,0.13829633186814977,0.5388920140603658,1.4703817232301912,0.3321505284860475,0.7572541827182976,-0.0009917498407377972,-0.2263016271137345,1.2073587193318431,2.1325052522465455,4.841737850614046,0.7033333538782307,0.5388920140603658,1.5186175105719402,0.3321505284860475,-1.0758316877354026,-0.10239964490688236,0.8107434624970358,-0.4601221695313692 | 3,053 |
Liposaccharide metabolic process | 11 | 21 | 2.53997 | 0.011086 | Q99805,Q8NBX0,P16278,Q99519,P06280,Q16739,Q8TCT0,P06865,Q9H490,P04062,P17900 | Processes and pathways | GO Biological process | msigdb_gobp | 128,451,65,132,231,136,169,386,106,56,186 | 729,1775,56,454,231,386,2598,65,186,1895,2539,2365,136,451,169,944,2823,2584,132,128,106 | 0.3321505284860475,-0.2681581692824456,2.861170882369116,0.6671420469276572,1.3401101108679196,0.7929611203043013,-0.6807859438462549,2.739955797601633,1.6299048673842986,-0.31030054118727124,-0.6360002154493802,-0.5254772864924734,1.998844642307609,0.6852623302074585,1.7239281707505134,0.17753878759272398,-0.9099290428795153,-0.6583511285219581,2.0585502205371826,2.1177736122329143,2.3213944057139972 | 3,053 |
Mental deterioration | 26 | 103 | 2.534804 | 0.011251 | O76024,P04350,Q9NZJ7,Q14108,Q9Y487,P50897,O75503,P27544,P54802,Q8NHS3,Q13510,P03886,P03915,O15118,P04062,P17900,Q9H2C2,O95470,Q9BQE5,P16278,O75306,Q92889,Q5XKP0,Q9Y287,P07602,Q15526 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 256,268,275,20,156,27,158,159,161,37,40,45,304,51,56,186,192,61,63,65,195,202,209,239,113,244 | 843,2397,51,872,625,556,528,2218,1370,195,158,256,628,2596,61,613,691,45,304,56,2130,268,847,386,113,2598,2936,2752,1257,2773,752,65,1417,186,825,1733,782,387,640,1735,159,2134,1677,366,456,2472,1467,1095,2268,2036,27,2504,2505,161,2141,2569,308,1688,1792,1522,2144,1575,1620,1958,677,698,833,40,20,1847,1755,244,2375,209,1856,807,1633,2992,2199,37,1045,2201,202,1860,2056,994,2847,2712,63,1442,2642,192,771,685,1656,275,892,1210,3009,1983,1324,239,156 | 0.23595476382188807,-0.5474201594629304,3.0329755799706857,0.21654186145358403,0.4269371803541035,0.5203652040028177,0.5573667616763491,-0.4601221695313692,-0.10239964490688236,1.566526139717696,1.8013490730391473,1.2073587193318431,0.4269371803541035,-0.6807859438462549,2.780573201657302,0.4457299111164649,0.3702313895262678,3.0850861706306985,1.0377463366595439,2.861170882369116,-0.4169396623740783,1.1737693798534528,0.23595476382188807,0.7929611203043013,2.2493125713395874,-0.6807859438462549,-1.1728161868952576,-0.8172019719548473,-0.04135865661767714,-0.8402469607675234,0.31302577253021713,2.739955797601633,-0.12287961106727112,1.6299048673842986,0.255309170150584,-0.24719447231895844,0.29384424374464585,0.7929611203043013,0.40809011351908236,-0.24719447231895844,1.7859314470019894,-0.4169396623740783,-0.2263016271137345,0.846167456483267,0.6671420469276572,-0.5915469880276591,-0.14342697267853247,0.05907835699925959,-0.48182900048661537,-0.37406084951540725,3.5515088405121995,-0.6137324247371202,-0.6137324247371202,1.7859314470019894,-0.4169396623740783,-0.6583511285219581,1.0205517659257686,-0.2263016271137345,-0.2681581692824456,-0.16404228682087726,-0.4169396623740783,-0.18472611797839597,-0.20547903817502652,-0.3314804483105227,0.3891883162351104,0.3702313895262678,0.255309170150584,3.162609148347032,3.863819674290911,-0.28919332161258265,-0.24719447231895844,1.2740517609654562,-0.5254772864924734,1.4703817232301912,-0.28919332161258265,0.2746055190128614,-0.20547903817502652,-1.5782524526378907,-0.4384926181619229,3.2010864353849686,0.09881078799017154,-0.4384926181619229,1.5186175105719402,-0.28919332161258265,-0.37406084951540725,0.13829633186814977,-0.9568488266934512,-0.7713802427604488,2.7670579060311247,-0.12287961106727112,-0.7033054530869399,1.6141131009311325,0.31302577253021713,0.3891883162351104,-0.20547903817502652,1.1569131412555997,0.21654186145358403,-0.0009917498407377972,-1.820052821881393,-0.3314804483105227,-0.061639706843019025,1.3071593288497105,1.8167337774526302 | 3,053 |
Cytochrome complex assembly | 6 | 11 | 2.527381 | 0.011492 | P53701,Q15070,Q7KZN9,Q6DKK2,Q9BSK2,Q9Y2R0 | Processes and pathways | GO Biological process | msigdb_gobp | 160,134,43,140,86,57 | 556,627,160,134,244,140,43,1650,86,2907,57 | 0.5203652040028177,0.4269371803541035,1.7859314470019894,2.0138167795559077,1.2740517609654562,1.9688079417064501,3.149741568733179,-0.20547903817502652,2.5056210267947026,-1.0758316877354026,2.861170882369116 | 3,053 |
Disproportionate short limb short stature | 7 | 20 | 2.519323 | 0.011758 | Q9BV10,Q14739,Q9UBM7,O75718,Q7LGA3,O00116,Q15392 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 103,41,269,180,279,119,29 | 119,1822,2431,180,752,1892,631,1373,1522,1796,41,29,736,678,279,354,1533,2741,103,269 | 2.1911393985906495,-0.28919332161258265,-0.5694431482641074,1.645661682349741,0.31302577253021713,-0.31030054118727124,0.4269371803541035,-0.10239964490688236,-0.16404228682087726,-0.2681581692824456,3.162609148347032,3.4405377784263176,0.3321505284860475,0.3891883162351104,1.1400155210794878,0.8989563120030468,-0.16404228682087726,-0.7942466885201216,2.3500331786247033,1.1737693798534528 | 3,053 |
Protein targeting | 29 | 102 | 2.517585 | 0.011816 | Q9NS69,Q99797,O60830,O14925,Q14108,Q99442,Q99595,P20645,P31751,O43615,Q15005,P61009,Q53H12,Q5JRX3,Q15629,Q9UNL2,P46379,O95831,P43307,Q8N4H5,Q9Y5M8,Q9P0J0,Q16543,Q9UHB9,Q9H9H4,O60725,O75381,Q9Y512,O14737 | Processes and pathways | GO Biological process | msigdb_gobp | 3,392,12,146,20,409,23,282,402,527,416,291,549,164,38,430,52,435,59,64,70,203,336,82,469,112,488,382,252 | 1820,2345,1365,1214,252,146,872,527,625,1295,112,12,488,2128,1085,1778,665,1086,1555,435,613,981,1672,2829,1217,1891,282,1835,826,2180,402,1221,1058,2265,2082,543,59,52,926,1060,756,2359,1098,674,1687,959,2818,291,2187,733,1688,1344,2188,1902,1520,588,677,1157,20,416,1105,38,2095,336,986,549,164,1635,2543,809,1801,2608,1434,1485,64,1804,2201,409,1397,1355,23,392,811,469,2949,3,2295,203,1247,867,82,708,747,841,2166,430,1143,2121,2618,382,2255,70 | -0.28919332161258265,-0.5254772864924734,-0.10239964490688236,-0.021142844948492293,1.2240923176202834,1.893169553532986,0.21654186145358403,0.5573667616763491,0.4269371803541035,-0.061639706843019025,2.2637848926817083,4.210058257772574,0.612482250975132,-0.4169396623740783,0.05907835699925959,-0.2681581692824456,0.3891883162351104,0.05907835699925959,-0.18472611797839597,0.7033333538782307,0.4457299111164649,0.13829633186814977,-0.2263016271137345,-0.9333418075172426,-0.021142844948492293,-0.31030054118727124,1.123076264470747,-0.28919332161258265,0.255309170150584,-0.4384926181619229,0.7572541827182976,-0.021142844948492293,0.07897567452569614,-0.48182900048661537,-0.3954626277985668,0.5388920140603658,2.8075327973843183,3.006789555372895,0.17753878759272398,0.07897567452569614,0.31302577253021713,-0.5254772864924734,0.05907835699925959,0.3891883162351104,-0.2263016271137345,0.15794771197129795,-0.9099290428795153,1.0890718099012444,-0.4384926181619229,0.3321505284860475,-0.2263016271137345,-0.08198652438815046,-0.4384926181619229,-0.31030054118727124,-0.16404228682087726,0.4831539193642934,0.3891883162351104,0.019095144049973707,3.863819674290911,0.7393289521585672,0.05907835699925959,3.1882814967797093,-0.3954626277985668,0.9339209551785153,0.13829633186814977,0.5388920140603658,1.7704807226942911,-0.20547903817502652,-0.6360002154493802,0.2746055190128614,-0.2681581692824456,-0.6807859438462549,-0.12287961106727112,-0.14342697267853247,2.7535188063677927,-0.2681581692824456,-0.4384926181619229,0.7572541827182976,-0.10239964490688236,-0.08198652438815046,3.8165416179463243,0.7929611203043013,0.2746055190128614,0.6489721670503341,-1.2219313118513195,4.841737850614046,-0.48182900048661537,1.5186175105719402,-0.021142844948492293,0.23595476382188807,2.547502565728995,0.3702313895262678,0.3321505284860475,0.255309170150584,-0.4169396623740783,0.7213554512800274,0.039118345533642226,-0.3954626277985668,-0.6807859438462549,0.8107434624970358,-0.4601221695313692,2.685462544005469 | 3,053 |
Maintenance of location | 13 | 69 | 2.514 | 0.011937 | Q9H6V9,P24390,P62942,P52789,P35610,O43731,P17900,Q14145,Q8NEW0,O95202,Q14534,P04062,Q8WTV0 | Processes and pathways | GO Biological process | msigdb_gobp | 0,1,98,226,258,7,186,235,49,148,183,56,26 | 2997,1214,294,729,7,2749,2699,558,820,474,148,846,1556,56,571,1055,2598,2433,2353,361,573,1459,2312,186,2532,2815,1,826,2702,1999,3017,1221,258,574,1095,1897,2889,226,98,600,1129,588,882,2365,1746,1157,235,183,1799,2835,2543,1435,49,26,2201,2894,1437,2847,2059,705,1286,463,0,635,1404,1657,1872,2210,1364 | -1.657669459103611,-0.021142844948492293,1.0720060894912629,0.3321505284860475,4.366865380443215,-0.8172019719548473,-0.7713802427604488,0.5203652040028177,0.255309170150584,0.6307523498834328,1.893169553532986,0.23595476382188807,-0.18472611797839597,2.861170882369116,0.5017859632503069,0.07897567452569614,-0.6807859438462549,-0.5694431482641074,-0.5254772864924734,0.8638097235543348,0.5017859632503069,-0.14342697267853247,-0.5036138048570713,1.6299048673842986,-0.6360002154493802,-0.9099290428795153,5.242039873099177,0.255309170150584,-0.7713802427604488,-0.35273367187282356,-2.13113769044908,-0.021142844948492293,1.2073587193318431,0.5017859632503069,0.05907835699925959,-0.31030054118727124,-1.0518387672424332,1.372905949710868,2.378562703431359,0.464468695655408,0.039118345533642226,0.4831539193642934,0.21654186145358403,-0.5254772864924734,-0.24719447231895844,0.019095144049973707,1.3236542021070108,1.645661682349741,-0.2681581692824456,-0.9333418075172426,-0.6360002154493802,-0.12287961106727112,3.072090978975674,3.588162517641911,-0.4384926181619229,-1.0518387672424332,-0.12287961106727112,-0.9568488266934512,-0.37406084951540725,0.3702313895262678,-0.04135865661767714,0.6671420469276572,5.909244161018679,0.4269371803541035,-0.10239964490688236,-0.20547903817502652,-0.28919332161258265,-0.4384926181619229,-0.08198652438815046 | 3,053 |
Calcium signaling pathway | 8 | 16 | 2.506267 | 0.012201 | P21796,P12235,P0DP25,P20020,P45880,Q9Y277,P05141,P12236 | Processes and pathways | KEGG Pathways | msigdb_kegg | 2,257,361,331,15,245,377,188 | 1557,377,361,257,188,436,2312,331,2,15,561,1958,2323,834,708,245 | -0.18472611797839597,0.8107434624970358,0.8638097235543348,1.2073587193318431,1.6141131009311325,0.7033333538782307,-0.5036138048570713,0.9513357791761082,4.914940523522634,4.096236762872413,0.5203652040028177,-0.3314804483105227,-0.5036138048570713,0.255309170150584,0.3702313895262678,1.2740517609654562 | 3,053 |
Central scotoma | 6 | 10 | 2.497276 | 0.012515 | O75306,Q8NHS3,P03886,Q9H6K4,Q9Y287,Q9H061 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 195,37,45,145,239,50 | 843,528,195,45,304,2533,37,50,145,239 | 0.23595476382188807,0.5573667616763491,1.566526139717696,3.0850861706306985,1.0377463366595439,-0.6360002154493802,3.2010864353849686,3.072090978975674,1.9537430602483536,1.3071593288497105 | 3,053 |
Hydrolase activity acting on glycosyl bonds | 12 | 32 | 2.492495 | 0.012685 | P54802,P16278,Q99519,P04066,P06280,O60502,P06865,O00754,Q9NUJ1,P04062,P17900,O75503 | Functions | GO Molecular function | msigdb_gomf | 161,65,132,454,231,104,386,383,111,56,186,158 | 623,383,2498,104,158,56,454,231,386,2598,596,573,2310,2072,65,186,1182,826,2355,1058,1150,161,1521,1910,2371,1854,2416,132,462,111,2556,1718 | 0.4269371803541035,0.7929611203043013,-0.6137324247371202,2.3357275135328175,1.8013490730391473,2.861170882369116,0.6671420469276572,1.3401101108679196,0.7929611203043013,-0.6807859438462549,0.464468695655408,0.5017859632503069,-0.5036138048570713,-0.3954626277985668,2.739955797601633,1.6299048673842986,-0.0009917498407377972,0.255309170150584,-0.5254772864924734,0.07897567452569614,0.019095144049973707,1.7859314470019894,-0.16404228682087726,-0.31030054118727124,-0.5254772864924734,-0.28919332161258265,-0.5474201594629304,2.0585502205371826,0.6671420469276572,2.278229101219084,-0.6360002154493802,-0.2263016271137345 | 3,053 |
Retrograde vesicle mediated transport golgi to endoplasmic reticulum | 6 | 23 | 2.486253 | 0.01291 | P24390,Q6NUQ1,O43731,Q9Y282,P18085,Q9P2W9 | Processes and pathways | GO Biological process | msigdb_gobp | 1,227,7,141,243,118 | 871,294,7,1671,243,1,829,1095,1373,529,544,1898,1377,2856,426,227,2288,1920,723,707,118,2338,141 | 0.21654186145358403,1.0720060894912629,4.366865380443215,-0.2263016271137345,1.2740517609654562,5.242039873099177,0.255309170150584,0.05907835699925959,-0.10239964490688236,0.5573667616763491,0.5388920140603658,-0.31030054118727124,-0.10239964490688236,-0.9804510545643588,0.7213554512800274,1.372905949710868,-0.48182900048661537,-0.31030054118727124,0.3512189297429039,0.3702313895262678,2.2057255535259004,-0.5036138048570713,1.9688079417064501 | 3,053 |
Arteriosclerosis | 8 | 18 | 2.481678 | 0.013077 | P16278,Q99519,Q13510,O75844,Q92889,P38435,O15118,P61916 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 65,132,40,72,202,107,51,308 | 51,2724,72,2501,2771,571,65,825,1090,1737,325,107,2898,308,40,606,202,132 | 3.0329755799706857,-0.7942466885201216,2.658069675513038,-0.6137324247371202,-0.8402469607675234,0.5017859632503069,2.739955797601633,0.255309170150584,0.05907835699925959,-0.24719447231895844,0.9687059891173524,2.307033723210691,-1.0758316877354026,1.0205517659257686,3.162609148347032,0.464468695655408,1.5186175105719402,2.0585502205371826 | 3,053 |
Hypocholesterolemia | 7 | 9 | 2.466403 | 0.013648 | Q9Y6B6,Q15800,P37268,Q9BV10,Q9UBM7,Q9NZJ7,P07602 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 397,95,197,103,269,275,113 | 113,197,2358,95,103,395,275,269,397 | 2.2493125713395874,1.5505926056196673,-0.5254772864924734,2.392786822066208,2.3500331786247033,0.7929611203043013,1.1569131412555997,1.1737693798534528,0.7929611203043013 | 3,053 |
Organelle membrane contact site | 11 | 15 | 2.461004 | 0.013855 | P51572,O95772,Q9Y320,Q96TC7,O96008,Q96N66,Q96S66,Q5XKP0,Q9NTJ5,Q14849,P27824 | Localization | GO Cellular component | msigdb_gocc | 674,68,431,428,613,175,767,209,744,30,502 | 1030,1880,749,68,613,502,674,30,1105,209,175,767,428,744,431 | 0.09881078799017154,-0.31030054118727124,0.31302577253021713,2.685462544005469,0.4457299111164649,0.5941615220565629,0.3891883162351104,3.428112577652922,0.05907835699925959,1.4703817232301912,1.6770712269532793,0.31302577253021713,0.7213554512800274,0.3321505284860475,0.7213554512800274 | 3,053 |
Ion transmembrane transport | 51 | 151 | 2.454351 | 0.014114 | P21796,Q9C0H2,P12235,P05023,P45880,O95202,O75915,P53985,Q9UJS0,O00400,Q96PU5,O75964,Q9UBX3,Q8TB61,Q4KMQ2,Q7KZN9,O60831,P20674,P03915,Q8NEW0,P04920,Q9UHG3,Q6P4A7,Q8IUH4,P16615,P12236,Q8NE86,Q9HC07,O75844,P20020,P13073,Q9HD20,Q9HC21,Q13423,P30825,Q96ES6,Q9UDW1,P08183,P62942,Q99623,Q9Y619,Q9H2D1,P41440,P0DP25,P24539,O43772,Q15526,Q9Y277,Q13546,Q70HW3,P05141 | Processes and pathways | GO Biological process | msigdb_gobp | 2,6,257,264,15,148,271,403,151,154,286,35,36,39,296,43,420,421,304,49,305,54,309,184,436,188,452,196,72,331,330,211,339,88,214,91,92,349,98,358,365,109,362,361,238,241,244,245,250,251,377 | 2023,154,952,1452,241,690,1880,2749,420,1369,2174,1177,2350,2128,819,72,271,977,35,148,691,304,305,264,847,377,1940,1731,1055,2895,1505,2433,2353,349,1125,614,572,361,1507,1297,257,188,330,436,2312,331,421,1462,2264,2815,2,238,2656,826,2438,1999,214,828,3035,1222,456,2472,362,1095,15,1953,2776,673,927,1152,1101,403,1340,577,1010,830,1063,1470,733,1344,98,1129,2277,648,588,531,757,1104,1620,2365,2682,1157,88,250,985,1913,1389,1695,244,1630,296,2874,309,2284,251,43,184,1435,1110,1702,550,452,49,39,1704,1972,91,1437,890,286,2847,358,1494,1650,1137,1244,6,769,2671,109,793,727,196,339,211,635,814,36,92,708,54,2209,151,796,1546,245,526,2618,1409,365,487 | -0.37406084951540725,1.8167337774526302,0.15794771197129795,-0.14342697267853247,1.2740517609654562,0.3702313895262678,-0.31030054118727124,-0.8172019719548473,0.7213554512800274,-0.10239964490688236,-0.4384926181619229,-0.0009917498407377972,-0.5254772864924734,-0.4169396623740783,0.255309170150584,2.658069675513038,1.1569131412555997,0.13829633186814977,3.2266342617272703,1.893169553532986,0.3702313895262678,1.0377463366595439,1.0377463366595439,1.1905844892407613,0.23595476382188807,0.8107434624970358,-0.3314804483105227,-0.24719447231895844,0.07897567452569614,-1.0758316877354026,-0.16404228682087726,-0.5694431482641074,-0.5254772864924734,0.8989563120030468,0.039118345533642226,0.4457299111164649,0.5017859632503069,0.8638097235543348,-0.16404228682087726,-0.061639706843019025,1.2073587193318431,1.6141131009311325,0.9513357791761082,0.7033333538782307,-0.5036138048570713,0.9513357791761082,0.7213554512800274,-0.14342697267853247,-0.48182900048661537,-0.9099290428795153,4.914940523522634,1.3071593288497105,-0.7259104599277266,0.255309170150584,-0.5694431482641074,-0.35273367187282356,1.4380399974777385,0.255309170150584,-2.7824586809976295,-0.021142844948492293,0.6671420469276572,-0.5915469880276591,0.8638097235543348,0.05907835699925959,4.096236762872413,-0.3314804483105227,-0.8402469607675234,0.3891883162351104,0.17753878759272398,0.019095144049973707,0.05907835699925959,0.7572541827182976,-0.08198652438815046,0.5017859632503069,0.11858418117435018,0.255309170150584,0.07897567452569614,-0.14342697267853247,0.3321505284860475,-0.08198652438815046,2.378562703431359,0.039118345533642226,-0.48182900048661537,0.40809011351908236,0.4831539193642934,0.5573667616763491,0.31302577253021713,0.05907835699925959,-0.20547903817502652,-0.5254772864924734,-0.7486017803237077,0.019095144049973707,2.4916088032578028,1.240785529211058,0.13829633186814977,-0.31030054118727124,-0.10239964490688236,-0.2263016271137345,1.2740517609654562,-0.20547903817502652,1.0720060894912629,-1.0041494608343033,1.0205517659257686,-0.48182900048661537,1.240785529211058,3.149741568733179,1.645661682349741,-0.12287961106727112,0.05907835699925959,-0.2263016271137345,0.5388920140603658,0.6852623302074585,3.072090978975674,3.1882814967797093,-0.2263016271137345,-0.3314804483105227,2.4352981359162196,-0.12287961106727112,0.21654186145358403,1.1060951140545585,-0.9568488266934512,0.881405908837468,-0.14342697267853247,-0.20547903817502652,0.039118345533642226,-0.021142844948492293,4.433189930630274,0.31302577253021713,-0.7259104599277266,2.2926453330472487,0.29384424374464585,0.3512189297429039,1.566526139717696,0.9339209551785153,1.4703817232301912,0.4269371803541035,0.2746055190128614,3.213870662525028,2.4352981359162196,0.3702313895262678,2.980515400984891,-0.4384926181619229,1.8626921049716938,0.29384424374464585,-0.16404228682087726,1.2740517609654562,0.5757898109834075,-0.6807859438462549,-0.10239964490688236,0.8638097235543348,0.6307523498834328 | 3,053 |
Copi dependent golgi to er retrograde traffic | 11 | 46 | 2.444678 | 0.014498 | Q9BVA1,P24390,Q6NUQ1,Q9Y3B3,O43731,Q86Y91,Q15363,P04350,O15260,P18085,Q9P2W9 | Processes and pathways | Reactome Pathways | msigdb_reactome | 263,1,227,69,7,201,139,268,110,243,118 | 2720,871,110,2525,7,2126,1671,2943,268,243,1,1464,829,1681,1373,544,1185,2476,1898,2089,1377,881,332,1103,1845,2368,440,1754,139,227,201,1487,1920,2517,2861,2153,480,263,2058,1116,592,1170,118,2338,69,1933 | -0.7942466885201216,0.21654186145358403,2.278229101219084,-0.6360002154493802,4.366865380443215,-0.4169396623740783,-0.2263016271137345,-1.2219313118513195,1.1737693798534528,1.2740517609654562,5.242039873099177,-0.14342697267853247,0.255309170150584,-0.2263016271137345,-0.10239964490688236,0.5388920140603658,-0.0009917498407377972,-0.5915469880276591,-0.31030054118727124,-0.3954626277985668,-0.10239964490688236,0.21654186145358403,0.9513357791761082,0.05907835699925959,-0.28919332161258265,-0.5254772864924734,0.7033333538782307,-0.24719447231895844,1.9688079417064501,1.372905949710868,1.5186175105719402,-0.14342697267853247,-0.31030054118727124,-0.6137324247371202,-0.9804510545643588,-0.4169396623740783,0.6307523498834328,1.2073587193318431,-0.37406084951540725,0.05907835699925959,0.4831539193642934,0.019095144049973707,2.2057255535259004,-0.5036138048570713,2.685462544005469,-0.31030054118727124 | 3,053 |
Glycosidase | 12 | 21 | 2.440901 | 0.014651 | P54802,P16278,P08236,Q99519,P04066,P10253,P06280,O60502,P06865,O00754,Q9BTY2,P04062 | Functions | Protein Atlas Molecular function | protein_atlas_molecular_function | 161,65,596,132,454,573,231,104,386,383,462,56 | 623,383,2498,104,56,454,231,386,2598,596,573,65,1058,1150,161,1521,1910,2371,1854,132,462 | 0.4269371803541035,0.7929611203043013,-0.6137324247371202,2.3357275135328175,2.861170882369116,0.6671420469276572,1.3401101108679196,0.7929611203043013,-0.6807859438462549,0.464468695655408,0.5017859632503069,2.739955797601633,0.07897567452569614,0.019095144049973707,1.7859314470019894,-0.16404228682087726,-0.31030054118727124,-0.5254772864924734,-0.28919332161258265,2.0585502205371826,0.6671420469276572 | 3,053 |
Passive transmembrane transporter activity | 8 | 36 | 2.437161 | 0.014803 | P21796,O75964,Q9C0H2,P39210,P24539,P45880,Q9Y277,Q9H813 | Functions | GO Molecular function | msigdb_gomf | 2,35,6,105,238,15,245,287 | 2023,977,35,613,1731,1055,2895,2353,572,2,238,2656,1222,2472,105,15,2776,927,1152,830,1063,733,588,2365,296,2874,452,1972,767,392,1137,6,287,814,1546,245 | -0.37406084951540725,0.13829633186814977,3.2266342617272703,0.4457299111164649,-0.24719447231895844,0.07897567452569614,-1.0758316877354026,-0.5254772864924734,0.5017859632503069,4.914940523522634,1.3071593288497105,-0.7259104599277266,-0.021142844948492293,-0.5915469880276591,2.3213944057139972,4.096236762872413,-0.8402469607675234,0.17753878759272398,0.019095144049973707,0.255309170150584,0.07897567452569614,0.3321505284860475,0.4831539193642934,-0.5254772864924734,1.0720060894912629,-1.0041494608343033,0.6852623302074585,-0.3314804483105227,0.31302577253021713,0.7929611203043013,0.039118345533642226,4.433189930630274,1.1060951140545585,0.2746055190128614,-0.16404228682087726,1.2740517609654562 | 3,053 |
Cherry red spot of the macula | 7 | 10 | 2.434718 | 0.014903 | P16278,Q99519,Q13510,Q9NZJ7,P07602,P10619,P17900 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 65,132,40,275,113,185,186 | 386,113,2598,185,2260,65,186,40,132,275 | 0.7929611203043013,2.2493125713395874,-0.6807859438462549,1.6299048673842986,-0.48182900048661537,2.739955797601633,1.6299048673842986,3.162609148347032,2.0585502205371826,1.1569131412555997 | 3,053 |
Glycoside hydrolase superfamily [IPR017853] | 10 | 17 | 2.434313 | 0.01492 | P16278,P54802,P08236,P04066,P06280,P10253,O60502,P06865,Q9BTY2,P04062 | Sequence | InterPro Superfamily | interpro_homologous_superfamily | 65,161,596,454,231,573,104,386,462,56 | 623,104,56,454,231,386,2598,1125,596,573,65,1150,161,2371,462,1074,1718 | 0.4269371803541035,2.3357275135328175,2.861170882369116,0.6671420469276572,1.3401101108679196,0.7929611203043013,-0.6807859438462549,0.039118345533642226,0.464468695655408,0.5017859632503069,2.739955797601633,0.019095144049973707,1.7859314470019894,-0.5254772864924734,0.6671420469276572,0.07897567452569614,-0.2263016271137345 | 3,053 |
Steroid biosynthesis | 7 | 10 | 2.431731 | 0.015027 | Q15800,P35610,P37268,Q9UBM7,Q14534,Q16850,Q15392 | Processes and pathways | KEGG Pathways | msigdb_kegg | 95,258,197,269,183,60,29 | 258,197,2898,326,183,29,2280,95,60,269 | 1.2073587193318431,1.5505926056196673,-1.0758316877354026,0.9687059891173524,1.645661682349741,3.4405377784263176,-0.48182900048661537,2.392786822066208,2.794064797575269,1.1737693798534528 | 3,053 |
Abnormal enchondral ossification | 13 | 29 | 2.430607 | 0.015074 | Q9NUQ7,O00116,Q99519,Q9UG56,Q14739,Q9Y619,P38435,Q9UBM7,Q96HY6,O95202,O75381,O96028,Q7RTS9 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 524,119,132,200,41,365,107,269,400,148,488,181,354 | 119,2431,488,148,181,596,752,2815,1680,107,543,2359,2187,1383,1193,41,1754,2280,1069,354,1533,400,2689,132,524,269,200,2343,365 | 2.1911393985906495,-0.5694431482641074,0.612482250975132,1.893169553532986,1.645661682349741,0.464468695655408,0.31302577253021713,-0.9099290428795153,-0.2263016271137345,2.307033723210691,0.5388920140603658,-0.5254772864924734,-0.4384926181619229,-0.10239964490688236,-0.0009917498407377972,3.162609148347032,-0.24719447231895844,-0.48182900048661537,0.07897567452569614,0.8989563120030468,-0.16404228682087726,0.7751314656744809,-0.7486017803237077,2.0585502205371826,0.5757898109834075,1.1737693798534528,1.5346231303445235,-0.5036138048570713,0.8638097235543348 | 3,053 |
transfer/carrier protein | 9 | 12 | 2.429638 | 0.015114 | O15126,Q9Y5M8,P12235,O15127,O14828,P17900,Q969E2,P05141,P12236 | Functions | Panther Protein class | panther_protein_class | 501,70,257,80,270,186,220,377,188 | 270,501,80,2499,377,257,188,186,2078,533,220,70 | 1.1569131412555997,0.5941615220565629,2.5614117640389127,-0.6137324247371202,0.8107434624970358,1.2073587193318431,1.6141131009311325,1.6299048673842986,-0.3954626277985668,0.5573667616763491,1.405548653662622,2.685462544005469 | 3,053 |
Endoplasmic reticulum to golgi vesicle mediated transport | 18 | 65 | 2.424937 | 0.015311 | Q9Y6B6,P24390,Q6NUQ1,Q12907,Q9Y3B3,O00743,O43731,Q13190,Q15436,Q15363,Q6DD88,Q9Y282,Q9HCU5,Q8NHH9,O95070,P18085,Q9P2W9,Q9NR31 | Processes and pathways | GO Biological process | msigdb_gobp | 397,1,227,426,69,344,7,495,517,139,301,141,499,337,370,243,118,483 | 344,871,1772,612,2525,7,1935,896,1671,1330,370,780,1993,923,2881,243,1,829,1373,926,544,674,851,2476,1898,1841,2569,1307,881,426,495,1962,139,517,1270,301,227,2101,908,1070,337,2288,1920,2201,988,723,2058,1170,1541,499,635,483,2389,118,2338,2614,2696,141,1249,1771,69,2619,1933,397,1662 | 0.8989563120030468,0.21654186145358403,-0.2681581692824456,0.4457299111164649,-0.6360002154493802,4.366865380443215,-0.3314804483105227,0.1970700191478118,-0.2263016271137345,-0.08198652438815046,0.8284788048032764,0.29384424374464585,-0.35273367187282356,0.17753878759272398,-1.0279450311062537,1.2740517609654562,5.242039873099177,0.255309170150584,-0.10239964490688236,0.17753878759272398,0.5388920140603658,0.3891883162351104,0.23595476382188807,-0.5915469880276591,-0.31030054118727124,-0.28919332161258265,-0.6583511285219581,-0.061639706843019025,0.21654186145358403,0.7213554512800274,0.612482250975132,-0.3314804483105227,1.9688079417064501,0.5757898109834075,-0.04135865661767714,1.0548976876796043,1.372905949710868,-0.3954626277985668,0.1970700191478118,0.07897567452569614,0.9339209551785153,-0.48182900048661537,-0.31030054118727124,-0.4384926181619229,0.13829633186814977,0.3512189297429039,-0.37406084951540725,0.019095144049973707,-0.16404228682087726,0.612482250975132,0.4269371803541035,0.6307523498834328,-0.5254772864924734,2.2057255535259004,-0.5036138048570713,-0.6807859438462549,-0.7486017803237077,1.9688079417064501,-0.021142844948492293,-0.24719447231895844,2.685462544005469,-0.6807859438462549,-0.31030054118727124,0.7929611203043013,-0.20547903817502652 | 3,053 |
Scotoma | 6 | 13 | 2.424901 | 0.015313 | O75306,Q8NHS3,P03886,Q9H6K4,Q9Y287,Q9H061 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 195,37,45,145,239,50 | 843,1666,528,195,45,304,692,2533,37,2783,50,145,239 | 0.23595476382188807,-0.2263016271137345,0.5573667616763491,1.566526139717696,3.0850861706306985,1.0377463366595439,0.3702313895262678,-0.6360002154493802,3.2010864353849686,-0.8402469607675234,3.072090978975674,1.9537430602483536,1.3071593288497105 | 3,053 |
Organic acid transmembrane transporter activity | 9 | 18 | 2.424818 | 0.015316 | Q9UBX3,Q9Y619,Q96QD8,Q9H2D1,P41440,P53985,Q9UJS0,P30825,P08183 | Functions | GO Molecular function | msigdb_gomf | 36,365,498,109,362,403,151,214,349 | 819,349,1125,214,362,1101,403,531,1630,2686,890,498,109,793,727,36,151,365 | 0.255309170150584,0.8989563120030468,0.039118345533642226,1.4380399974777385,0.8638097235543348,0.05907835699925959,0.7572541827182976,0.5573667616763491,-0.20547903817502652,-0.7486017803237077,0.21654186145358403,0.612482250975132,2.2926453330472487,0.29384424374464585,0.3512189297429039,3.213870662525028,1.8626921049716938,0.8638097235543348 | 3,053 |
Steroid biosynthesis | 7 | 16 | 2.418587 | 0.015581 | Q15800,P37268,Q14739,Q9UBM7,Q53GQ0,Q16850,Q15392 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 95,197,41,269,283,60,29 | 1826,1259,197,326,2920,2574,41,1914,29,2280,95,60,283,590,2492,269 | -0.28919332161258265,-0.04135865661767714,1.5505926056196673,0.9687059891173524,-1.1241192412166017,-0.6583511285219581,3.162609148347032,-0.31030054118727124,3.4405377784263176,-0.48182900048661537,2.392786822066208,2.794064797575269,1.123076264470747,0.4831539193642934,-0.5915469880276591,1.1737693798534528 | 3,053 |
Postural tremor | 7 | 16 | 2.387986 | 0.016941 | O75569,O75306,P04350,P03886,Q9H6K4,P03915,Q14108 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 347,195,268,45,145,304,20 | 624,1987,195,347,1993,45,304,268,1733,366,2141,1620,20,2847,145,1983 | 0.4269371803541035,-0.35273367187282356,1.566526139717696,0.8989563120030468,-0.35273367187282356,3.0850861706306985,1.0377463366595439,1.1737693798534528,-0.24719447231895844,0.846167456483267,-0.4169396623740783,-0.20547903817502652,3.863819674290911,-0.9568488266934512,1.9537430602483536,-0.3314804483105227 | 3,053 |
Variable expressivity | 15 | 70 | 2.386793 | 0.016996 | Q9BVA1,Q13510,P04350,P03886,Q9NZJ7,P03915,Q9H061,P07602,P00374,Q15526,Q6P4A7,P17900,Q70HW3,Q9Y5P6,O95470 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 263,40,268,45,275,304,50,113,84,244,309,186,251,316,61 | 843,1452,1775,2750,1254,61,84,691,2771,45,304,268,2223,1147,113,1181,2752,1781,639,186,1514,1567,1895,2472,1223,2318,1897,2268,2036,1741,2140,1185,1128,2569,1227,2571,1690,1792,2681,2368,716,40,1579,1693,440,2371,1963,244,549,2760,309,807,251,1533,480,1539,263,50,1542,1171,1141,275,2391,1173,355,2907,1770,2827,1409,316 | 0.23595476382188807,-0.14342697267853247,-0.2681581692824456,-0.8172019719548473,-0.04135865661767714,2.780573201657302,2.519607315435531,0.3702313895262678,-0.8402469607675234,3.0850861706306985,1.0377463366595439,1.1737693798534528,-0.4601221695313692,0.019095144049973707,2.2493125713395874,-0.0009917498407377972,-0.8172019719548473,-0.2681581692824456,0.40809011351908236,1.6299048673842986,-0.16404228682087726,-0.18472611797839597,-0.31030054118727124,-0.5915469880276591,-0.021142844948492293,-0.5036138048570713,-0.31030054118727124,-0.48182900048661537,-0.37406084951540725,-0.24719447231895844,-0.4169396623740783,-0.0009917498407377972,0.039118345533642226,-0.6583511285219581,-0.021142844948492293,-0.6583511285219581,-0.2263016271137345,-0.2681581692824456,-0.7486017803237077,-0.5254772864924734,0.3512189297429039,3.162609148347032,-0.18472611797839597,-0.2263016271137345,0.7033333538782307,-0.5254772864924734,-0.3314804483105227,1.2740517609654562,0.5388920140603658,-0.8172019719548473,1.0205517659257686,0.2746055190128614,1.240785529211058,-0.16404228682087726,0.6307523498834328,-0.16404228682087726,1.2073587193318431,3.072090978975674,-0.16404228682087726,0.019095144049973707,0.039118345533642226,1.1569131412555997,-0.5254772864924734,0.019095144049973707,0.8989563120030468,-1.0758316877354026,-0.24719447231895844,-0.9099290428795153,-0.10239964490688236,1.0033137022368463 | 3,053 |
Electron transport | 14 | 45 | 2.383083 | 0.017168 | Q16134,O75306,Q9H1E5,Q9P0J0,Q6DKK2,P03886,Q86Y39,O14949,P03915,O43676,Q96CU9,Q9UDW1,O75438,O43169 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 189,195,165,203,140,45,204,142,304,47,281,92,126,31 | 952,142,31,1251,47,1177,195,126,384,434,628,1604,978,979,595,691,45,304,614,2311,1298,1831,782,2533,324,3014,2134,828,3035,2817,2183,783,189,2413,650,2510,140,204,281,1437,165,522,203,92,1053 | 0.15794771197129795,1.9537430602483536,3.4032042415630985,-0.04135865661767714,3.072090978975674,-0.0009917498407377972,1.566526139717696,2.1618805177312446,0.7929611203043013,0.7033333538782307,0.4269371803541035,-0.20547903817502652,0.13829633186814977,0.13829633186814977,0.464468695655408,0.3702313895262678,3.0850861706306985,1.0377463366595439,0.4457299111164649,-0.5036138048570713,-0.061639706843019025,-0.28919332161258265,0.29384424374464585,-0.6360002154493802,0.9687059891173524,-1.959204894557855,-0.4169396623740783,0.255309170150584,-2.7824586809976295,-0.9099290428795153,-0.4384926181619229,0.29384424374464585,1.6141131009311325,-0.5474201594629304,0.40809011351908236,-0.6137324247371202,1.9688079417064501,1.502575541135129,1.1400155210794878,-0.12287961106727112,1.7549967219478475,0.5757898109834075,1.5186175105719402,2.4352981359162196,0.09881078799017154 | 3,053 |
Lipid homeostasis | 12 | 27 | 2.381328 | 0.01725 | Q9Y6B6,Q96CP7,Q15067,P35610,P34913,O15260,O15118,Q5BJF2,P61916,Q8WTV0,Q9NQC3,Q86YV9 | Processes and pathways | GO Biological process | msigdb_gobp | 397,193,259,258,325,110,51,116,308,26,123,450 | 1366,51,110,923,2501,571,2261,1093,325,258,308,3031,259,116,1483,2284,450,26,193,2894,967,463,123,2648,1716,397,971 | -0.10239964490688236,3.0329755799706857,2.278229101219084,0.17753878759272398,-0.6137324247371202,0.5017859632503069,-0.48182900048661537,0.05907835699925959,0.9687059891173524,1.2073587193318431,1.0205517659257686,-2.493024635127748,1.2073587193318431,2.2057255535259004,-0.14342697267853247,-0.48182900048661537,0.6852623302074585,3.588162517641911,1.598286188567672,-1.0518387672424332,0.15794771197129795,0.6671420469276572,2.1765244342071473,-0.7033054530869399,-0.2263016271137345,0.7929611203043013,0.15794771197129795 | 3,053 |
Abnormality of corneal stroma | 7 | 17 | 2.379966 | 0.017314 | P16278,O43505,P34913,Q13510,Q92889,P04062,P10619 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 65,345,325,40,202,56,185 | 345,2501,56,571,185,65,825,1090,325,2359,2141,1574,602,40,406,1631,202 | 0.8989563120030468,-0.6137324247371202,2.861170882369116,0.5017859632503069,1.6299048673842986,2.739955797601633,0.255309170150584,0.05907835699925959,0.9687059891173524,-0.5254772864924734,-0.4169396623740783,-0.18472611797839597,0.464468695655408,3.162609148347032,0.7572541827182976,-0.20547903817502652,1.5186175105719402 | 3,053 |
Respiratory electron transport | 21 | 51 | 2.369591 | 0.017808 | O75489,O14949,P03886,P20674,P03915,O43676,O43819,O95168,Q16134,O75306,P22695,Q9P0J0,Q86Y39,P13073,Q9UDW1,O96000,P08574,Q15526,O95169,O75880,O75438 | Processes and pathways | Reactome Pathways | msigdb_reactome | 384,142,45,421,304,47,556,434,189,195,324,203,204,330,92,595,614,244,628,627,126 | 952,142,47,556,1177,195,126,384,627,434,628,1604,978,595,691,45,304,614,1458,1507,330,2311,1298,1889,1831,421,782,324,3014,2134,828,2817,1467,2183,783,1907,244,189,2413,650,1637,204,1441,1650,1442,1050,771,2522,203,92,1053 | 0.15794771197129795,1.9537430602483536,3.072090978975674,0.5203652040028177,-0.0009917498407377972,1.566526139717696,2.1618805177312446,0.7929611203043013,0.4269371803541035,0.7033333538782307,0.4269371803541035,-0.20547903817502652,0.13829633186814977,0.464468695655408,0.3702313895262678,3.0850861706306985,1.0377463366595439,0.4457299111164649,-0.14342697267853247,-0.16404228682087726,0.9513357791761082,-0.5036138048570713,-0.061639706843019025,-0.31030054118727124,-0.28919332161258265,0.7213554512800274,0.29384424374464585,0.9687059891173524,-1.959204894557855,-0.4169396623740783,0.255309170150584,-0.9099290428795153,-0.14342697267853247,-0.4384926181619229,0.29384424374464585,-0.31030054118727124,1.2740517609654562,1.6141131009311325,-0.5474201594629304,0.40809011351908236,-0.20547903817502652,1.502575541135129,-0.12287961106727112,-0.20547903817502652,-0.12287961106727112,0.09881078799017154,0.31302577253021713,-0.6137324247371202,1.5186175105719402,2.4352981359162196,0.09881078799017154 | 3,053 |
Huntingtons disease | 19 | 76 | 2.365035 | 0.018028 | P21796,P12235,O75489,O14949,Q96CW1,P45880,P20674,P30876,O43676,P12236,O75306,P22695,P13073,P14406,Q9UDW1,P24539,Q9Y277,P05141,O75438 | Processes and pathways | KEGG Pathways | msigdb_kegg | 2,257,384,142,274,15,421,300,47,188,195,324,330,85,92,238,245,377,126 | 2301,952,142,47,1177,195,126,384,977,1729,434,628,1604,978,2983,595,691,1938,2352,377,1731,614,629,1559,1458,1507,257,188,330,85,1298,1889,2946,1419,1831,421,2,782,324,238,2626,2656,826,3014,300,2134,828,1222,1466,1095,15,2776,2183,783,1615,2232,1471,1617,832,1792,2365,2323,1475,905,1847,1695,2413,650,1971,274,2382,92,970,1601,245,1053 | -0.5036138048570713,0.15794771197129795,1.9537430602483536,3.072090978975674,-0.0009917498407377972,1.566526139717696,2.1618805177312446,0.7929611203043013,0.13829633186814977,-0.24719447231895844,0.7033333538782307,0.4269371803541035,-0.20547903817502652,0.13829633186814977,-1.4741094280213356,0.464468695655408,0.3702313895262678,-0.3314804483105227,-0.5254772864924734,0.8107434624970358,-0.24719447231895844,0.4457299111164649,0.4269371803541035,-0.18472611797839597,-0.14342697267853247,-0.16404228682087726,1.2073587193318431,1.6141131009311325,0.9513357791761082,2.5056210267947026,-0.061639706843019025,-0.31030054118727124,-1.2219313118513195,-0.12287961106727112,-0.28919332161258265,0.7213554512800274,4.914940523522634,0.29384424374464585,0.9687059891173524,1.3071593288497105,-0.7033054530869399,-0.7259104599277266,0.255309170150584,-1.959204894557855,1.0548976876796043,-0.4169396623740783,0.255309170150584,-0.021142844948492293,-0.14342697267853247,0.05907835699925959,4.096236762872413,-0.8402469607675234,-0.4384926181619229,0.29384424374464585,-0.20547903817502652,-0.4601221695313692,-0.14342697267853247,-0.20547903817502652,0.255309170150584,-0.2681581692824456,-0.5254772864924734,-0.5036138048570713,-0.14342697267853247,0.1970700191478118,-0.28919332161258265,-0.2263016271137345,-0.5474201594629304,0.40809011351908236,-0.3314804483105227,1.1569131412555997,-0.5254772864924734,2.4352981359162196,0.15794771197129795,-0.18472611797839597,1.2740517609654562,0.09881078799017154 | 3,053 |
Vacuolar acidification | 6 | 9 | 2.364486 | 0.018055 | Q9P0T7,Q9Y487,Q93050,Q8N511,P50897,O75503 | Processes and pathways | GO Biological process | msigdb_gobp | 396,156,121,58,27,158 | 158,446,27,1470,58,121,396,2209,156 | 1.8013490730391473,0.6852623302074585,3.5515088405121995,-0.14342697267853247,2.834398419466517,2.1911393985906495,0.7929611203043013,-0.4384926181619229,1.8167337774526302 | 3,053 |
Alzheimers disease | 25 | 81 | 2.350432 | 0.018752 | Q9BVA1,P21796,P12235,P04350,P45880,Q92542,P31751,P60900,P20618,Q13885,P49721,P16615,P12236,Q8NE86,P28072,P68371,O95197,P07437,Q9Y4P8,P49327,P48729,P0DP25,Q9Y277,Q9NQC3,P05141 | Processes and pathways | WikiPathways | msigdb_wp | 263,2,257,268,15,408,402,172,177,440,55,436,188,452,76,332,78,348,224,229,234,361,245,123,377 | 2721,2674,776,2652,844,1665,1176,78,268,1939,847,377,801,1505,348,361,257,188,2074,436,2974,1218,1563,1891,177,2,1946,2562,2227,2228,2133,2079,2727,924,76,669,1736,2438,3017,402,1464,1678,2470,631,1466,2660,15,1614,234,229,755,55,1009,2794,172,1229,1843,2044,1423,332,588,1904,1845,2442,1958,2323,1623,548,440,1159,452,408,1396,1973,2712,480,263,123,1984,245,224 | -0.7942466885201216,-0.7486017803237077,0.29384424374464585,-0.7259104599277266,0.23595476382188807,-0.2263016271137345,-0.0009917498407377972,2.575295500784994,1.1737693798534528,-0.3314804483105227,0.23595476382188807,0.8107434624970358,0.2746055190128614,-0.16404228682087726,0.8989563120030468,0.8638097235543348,1.2073587193318431,1.6141131009311325,-0.3954626277985668,0.7033333538782307,-1.397261622755791,-0.021142844948492293,-0.18472611797839597,-0.31030054118727124,1.661383738534994,4.914940523522634,-0.3314804483105227,-0.6583511285219581,-0.4601221695313692,-0.4601221695313692,-0.4169396623740783,-0.3954626277985668,-0.7942466885201216,0.17753878759272398,2.6029870534417396,0.3891883162351104,-0.24719447231895844,-0.5694431482641074,-2.13113769044908,0.7572541827182976,-0.14342697267853247,-0.2263016271137345,-0.5915469880276591,0.4269371803541035,-0.14342697267853247,-0.7259104599277266,4.096236762872413,-0.20547903817502652,1.3236542021070108,1.3565272843725606,0.31302577253021713,2.927699712335164,0.11858418117435018,-0.8633825363003653,1.6770712269532793,-0.021142844948492293,-0.28919332161258265,-0.37406084951540725,-0.12287961106727112,0.9513357791761082,0.4831539193642934,-0.31030054118727124,-0.28919332161258265,-0.5694431482641074,-0.3314804483105227,-0.5036138048570713,-0.20547903817502652,0.5388920140603658,0.7033333538782307,0.019095144049973707,0.6852623302074585,0.7572541827182976,-0.10239964490688236,-0.3314804483105227,-0.7713802427604488,0.6307523498834328,1.2073587193318431,2.1765244342071473,-0.3314804483105227,1.2740517609654562,1.3892463318502195 | 3,053 |
Regulation of hormone levels | 17 | 58 | 2.34855 | 0.018847 | Q8NE86,Q16822,P16435,Q06520,Q6NUM9,P05023,O75844,Q9UBM7,Q16836,P42892,O15382,P53985,Q9HB40,O95470,Q53GQ0,Q14849,P07858 | Processes and pathways | GO Biological process | msigdb_gobp | 452,447,323,4,448,264,72,269,352,212,277,403,53,61,283,30,223 | 2427,972,277,2400,749,1669,446,72,61,1605,2772,264,223,2433,2465,1181,2074,1828,323,1608,615,1832,1999,1951,212,2937,1099,851,403,881,2844,4,1958,2233,834,30,1389,1629,447,352,283,448,1635,1858,582,590,452,2487,1437,2382,2847,2712,53,1765,269,1983,1548,815 | -0.5694431482641074,0.13829633186814977,1.1400155210794878,-0.5474201594629304,0.31302577253021713,-0.2263016271137345,0.6852623302074585,2.658069675513038,2.780573201657302,-0.20547903817502652,-0.8402469607675234,1.1905844892407613,1.3892463318502195,-0.5694431482641074,-0.5915469880276591,-0.0009917498407377972,-0.3954626277985668,-0.28919332161258265,0.9687059891173524,-0.20547903817502652,0.4457299111164649,-0.28919332161258265,-0.35273367187282356,-0.3314804483105227,1.4542294549861097,-1.1728161868952576,0.05907835699925959,0.23595476382188807,0.7572541827182976,0.21654186145358403,-0.9568488266934512,4.564311687934693,-0.3314804483105227,-0.4601221695313692,0.255309170150584,3.428112577652922,-0.10239964490688236,-0.20547903817502652,0.6852623302074585,0.8989563120030468,1.123076264470747,0.6852623302074585,-0.20547903817502652,-0.28919332161258265,0.5017859632503069,0.4831539193642934,0.6852623302074585,-0.5915469880276591,-0.12287961106727112,-0.5254772864924734,-0.9568488266934512,-0.7713802427604488,3.006789555372895,-0.24719447231895844,1.1737693798534528,-0.3314804483105227,-0.16404228682087726,0.2746055190128614 | 3,053 |
Protein insertion into membrane | 7 | 26 | 2.347039 | 0.018923 | Q9NS69,Q15629,Q15070,Q9P0J0,Q96A33,P46379,O14737 | Processes and pathways | GO Biological process | msigdb_gobp | 3,38,134,203,306,52,252 | 252,1294,625,1295,1778,1557,981,850,2265,52,733,2365,2010,134,38,549,2543,550,1044,306,2591,3,203,2907,382,2255 | 1.2240923176202834,-0.061639706843019025,0.4269371803541035,-0.061639706843019025,-0.2681581692824456,-0.18472611797839597,0.13829633186814977,0.23595476382188807,-0.48182900048661537,3.006789555372895,0.3321505284860475,-0.5254772864924734,-0.35273367187282356,2.0138167795559077,3.1882814967797093,0.5388920140603658,-0.6360002154493802,0.5388920140603658,0.09881078799017154,1.0377463366595439,-0.6583511285219581,4.841737850614046,1.5186175105719402,-1.0758316877354026,0.8107434624970358,-0.4601221695313692 | 3,053 |
Carbohydrate derivative transmembrane transporter activity | 7 | 10 | 2.343501 | 0.019104 | L0R6Q1,P12235,Q8TB61,P41440,O00400,P05141,P12236 | Functions | GO Molecular function | msigdb_gomf | 412,257,39,362,154,377,188 | 412,154,690,377,257,188,362,534,39,1023 | 0.7393289521585672,1.8167337774526302,0.3702313895262678,0.8107434624970358,1.2073587193318431,1.6141131009311325,0.8638097235543348,0.5573667616763491,3.1882814967797093,0.11858418117435018 | 3,053 |
transferase | 9 | 31 | 2.340861 | 0.019239 | O14735,O43505,Q06520,P37268,O15217,P43490,O14880,Q7LGA3,Q9Y5P6 | Functions | Panther Protein class | panther_protein_class | 322,345,4,197,100,74,368,279,316 | 322,368,100,345,2787,846,1780,1560,2075,1461,898,850,2316,197,74,672,1840,1743,931,4,2194,374,279,2845,1203,862,1138,1025,470,2254,316 | 0.9687059891173524,0.8284788048032764,2.3500331786247033,0.8989563120030468,-0.8633825363003653,0.23595476382188807,-0.2681581692824456,-0.18472611797839597,-0.3954626277985668,-0.14342697267853247,0.1970700191478118,0.23595476382188807,-0.5036138048570713,1.5505926056196673,2.63057814300429,0.3891883162351104,-0.28919332161258265,-0.24719447231895844,0.17753878759272398,4.564311687934693,-0.4384926181619229,0.8284788048032764,1.1400155210794878,-0.9568488266934512,-0.0009917498407377972,0.23595476382188807,0.039118345533642226,0.11858418117435018,0.6489721670503341,-0.4601221695313692,1.0033137022368463 | 3,053 |
Endoplasmic reticulum golgi intermediate compartment | 13 | 48 | 2.329421 | 0.019837 | Q15904,P24390,Q12907,Q9Y3B3,O15258,Q15363,P80303,Q9Y282,O15260,O95070,Q10472,Q8N511,Q02818 | Localization | GO Cellular component | msigdb_gocc | 318,1,426,69,294,139,13,141,110,370,373,58,351 | 294,110,612,1671,370,693,1506,1,1610,2702,2774,1058,926,544,2918,674,2476,1127,2320,1307,13,351,424,373,426,495,581,2706,139,318,888,908,1070,58,1920,913,723,2058,1170,2460,2338,708,2341,141,1771,69,1933,1662 | 1.0720060894912629,2.278229101219084,0.4457299111164649,-0.2263016271137345,0.8284788048032764,0.3702313895262678,-0.16404228682087726,5.242039873099177,-0.20547903817502652,-0.7713802427604488,-0.8402469607675234,0.07897567452569614,0.17753878759272398,0.5388920140603658,-1.1241192412166017,0.3891883162351104,-0.5915469880276591,0.039118345533642226,-0.5036138048570713,-0.061639706843019025,4.18741722715009,0.8989563120030468,0.7213554512800274,0.8284788048032764,0.7213554512800274,0.612482250975132,0.5017859632503069,-0.7713802427604488,1.9688079417064501,0.9860318695770233,0.21654186145358403,0.1970700191478118,0.07897567452569614,2.834398419466517,-0.31030054118727124,0.1970700191478118,0.3512189297429039,-0.37406084951540725,0.019095144049973707,-0.5694431482641074,-0.5036138048570713,0.3702313895262678,-0.5036138048570713,1.9688079417064501,-0.24719447231895844,2.685462544005469,-0.31030054118727124,-0.20547903817502652 | 3,053 |
Lower limb spasticity | 20 | 72 | 2.328675 | 0.019876 | Q99519,Q6DKK2,O00754,Q9H6K4,O75489,Q9NZJ7,Q99720,Q96CU9,O00400,Q7KZN9,P04062,O95831,O75306,Q92889,Q9P0J0,Q5XKP0,Q9Y619,P35637,P07602,Q15526 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 132,140,383,145,384,275,24,281,154,43,56,435,195,202,203,209,365,366,113,244 | 154,843,952,383,528,1177,195,384,446,1726,2175,978,435,2070,2701,56,1505,113,848,1607,2829,639,2260,1831,782,3014,2853,2134,366,1895,2083,2358,2183,2568,2140,2505,1128,2141,2569,1569,1227,2368,2233,244,1585,650,2760,209,140,1632,43,653,1045,988,202,281,2332,1204,132,24,1650,1358,2159,145,2388,275,203,892,1983,2827,1409,365 | 1.8167337774526302,0.23595476382188807,0.15794771197129795,0.7929611203043013,0.5573667616763491,-0.0009917498407377972,1.566526139717696,0.7929611203043013,0.6852623302074585,-0.24719447231895844,-0.4384926181619229,0.13829633186814977,0.7033333538782307,-0.3954626277985668,-0.7713802427604488,2.861170882369116,-0.16404228682087726,2.2493125713395874,0.23595476382188807,-0.20547903817502652,-0.9333418075172426,0.40809011351908236,-0.48182900048661537,-0.28919332161258265,0.29384424374464585,-1.959204894557855,-0.9804510545643588,-0.4169396623740783,0.846167456483267,-0.31030054118727124,-0.3954626277985668,-0.5254772864924734,-0.4384926181619229,-0.6583511285219581,-0.4169396623740783,-0.6137324247371202,0.039118345533642226,-0.4169396623740783,-0.6583511285219581,-0.18472611797839597,-0.021142844948492293,-0.5254772864924734,-0.4601221695313692,1.2740517609654562,-0.18472611797839597,0.40809011351908236,-0.8172019719548473,1.4703817232301912,1.9688079417064501,-0.20547903817502652,3.149741568733179,0.40809011351908236,0.09881078799017154,0.13829633186814977,1.5186175105719402,1.1400155210794878,-0.5036138048570713,-0.0009917498407377972,2.0585502205371826,3.757058561044739,-0.20547903817502652,-0.08198652438815046,-0.4169396623740783,1.9537430602483536,-0.5254772864924734,1.1569131412555997,1.5186175105719402,0.21654186145358403,-0.3314804483105227,-0.9099290428795153,-0.10239964490688236,0.8638097235543348 | 3,053 |
Respiratory electron transport chain | 15 | 50 | 2.327632 | 0.019932 | Q16134,O75306,Q7KZN9,O75489,P03886,P20674,P13073,O14949,P03915,O43676,Q9UJS0,P04062,Q9UDW1,O75438,Q9H3K2 | Processes and pathways | GO Biological process | msigdb_gobp | 189,195,43,384,45,421,330,142,304,47,151,56,92,126,127 | 952,142,47,556,1177,195,126,384,819,434,628,1604,978,595,691,45,304,56,1938,1558,614,1781,1507,330,2311,2224,1298,1889,1831,421,782,3014,2134,2817,599,2183,783,2901,189,2413,650,43,2847,1243,2671,127,793,92,151,1053 | 0.15794771197129795,1.9537430602483536,3.072090978975674,0.5203652040028177,-0.0009917498407377972,1.566526139717696,2.1618805177312446,0.7929611203043013,0.255309170150584,0.7033333538782307,0.4269371803541035,-0.20547903817502652,0.13829633186814977,0.464468695655408,0.3702313895262678,3.0850861706306985,1.0377463366595439,2.861170882369116,-0.3314804483105227,-0.18472611797839597,0.4457299111164649,-0.2681581692824456,-0.16404228682087726,0.9513357791761082,-0.5036138048570713,-0.4601221695313692,-0.061639706843019025,-0.31030054118727124,-0.28919332161258265,0.7213554512800274,0.29384424374464585,-1.959204894557855,-0.4169396623740783,-0.9099290428795153,0.464468695655408,-0.4384926181619229,0.29384424374464585,-1.0758316877354026,1.6141131009311325,-0.5474201594629304,0.40809011351908236,3.149741568733179,-0.9568488266934512,-0.021142844948492293,-0.7259104599277266,2.1325052522465455,0.29384424374464585,2.4352981359162196,1.8626921049716938,0.09881078799017154 | 3,053 |
Alzheimers disease and mirna effects | 25 | 82 | 2.321527 | 0.020258 | Q9BVA1,P21796,P12235,P04350,P45880,Q92542,P31751,P60900,P20618,Q13885,P49721,P16615,P12236,Q8NE86,P28072,P68371,O95197,P07437,Q9Y4P8,P49327,P48729,P0DP25,Q9Y277,Q9NQC3,P05141 | Processes and pathways | WikiPathways | msigdb_wp | 263,2,257,268,15,408,402,172,177,440,55,436,188,452,76,332,78,348,224,229,234,361,245,123,377 | 2721,2674,776,2652,844,1665,1176,78,268,1939,847,377,801,1505,348,361,257,188,2074,436,2974,1218,1563,1891,177,2,1946,2562,2227,2228,2133,2079,2727,924,76,669,1736,2438,3017,402,1464,1678,2470,631,1466,2660,15,1614,234,229,755,55,1009,2794,172,1229,1843,2044,1423,332,588,1904,1845,2442,1958,2323,1623,548,440,1159,452,408,965,1396,1973,2712,480,263,123,1984,245,224 | -0.7942466885201216,-0.7486017803237077,0.29384424374464585,-0.7259104599277266,0.23595476382188807,-0.2263016271137345,-0.0009917498407377972,2.575295500784994,1.1737693798534528,-0.3314804483105227,0.23595476382188807,0.8107434624970358,0.2746055190128614,-0.16404228682087726,0.8989563120030468,0.8638097235543348,1.2073587193318431,1.6141131009311325,-0.3954626277985668,0.7033333538782307,-1.397261622755791,-0.021142844948492293,-0.18472611797839597,-0.31030054118727124,1.661383738534994,4.914940523522634,-0.3314804483105227,-0.6583511285219581,-0.4601221695313692,-0.4601221695313692,-0.4169396623740783,-0.3954626277985668,-0.7942466885201216,0.17753878759272398,2.6029870534417396,0.3891883162351104,-0.24719447231895844,-0.5694431482641074,-2.13113769044908,0.7572541827182976,-0.14342697267853247,-0.2263016271137345,-0.5915469880276591,0.4269371803541035,-0.14342697267853247,-0.7259104599277266,4.096236762872413,-0.20547903817502652,1.3236542021070108,1.3565272843725606,0.31302577253021713,2.927699712335164,0.11858418117435018,-0.8633825363003653,1.6770712269532793,-0.021142844948492293,-0.28919332161258265,-0.37406084951540725,-0.12287961106727112,0.9513357791761082,0.4831539193642934,-0.31030054118727124,-0.28919332161258265,-0.5694431482641074,-0.3314804483105227,-0.5036138048570713,-0.20547903817502652,0.5388920140603658,0.7033333538782307,0.019095144049973707,0.6852623302074585,0.7572541827182976,0.15794771197129795,-0.10239964490688236,-0.3314804483105227,-0.7713802427604488,0.6307523498834328,1.2073587193318431,2.1765244342071473,-0.3314804483105227,1.2740517609654562,1.3892463318502195 | 3,053 |
Reductase | 7 | 17 | 2.303257 | 0.021264 | Q14739,Q9UBM7,Q15392,P00374,O95168,Q9UDW1,O95881 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 41,269,29,84,434,92,253 | 1723,2623,434,253,84,2178,1298,1828,2226,1676,641,41,29,1966,481,269,92 | -0.24719447231895844,-0.7033054530869399,0.7033333538782307,1.2240923176202834,2.519607315435531,-0.4384926181619229,-0.061639706843019025,-0.28919332161258265,-0.4601221695313692,-0.2263016271137345,0.40809011351908236,3.162609148347032,3.4405377784263176,-0.3314804483105227,0.6307523498834328,1.1737693798534528,2.4352981359162196 | 3,053 |
Rigidity | 11 | 55 | 2.302371 | 0.021314 | P16278,P12235,P04350,Q9H6K4,Q9NZJ7,Q9Y287,P07602,Q9H2C2,P04062,Q96CU9,Q15392 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 65,257,268,145,275,239,113,192,56,281,29 | 2397,872,625,1370,446,1726,2596,1256,56,268,113,257,65,1417,1563,828,1567,1261,2472,1095,2036,2038,2505,1185,1569,1688,1792,2144,1575,1620,1958,1847,29,1432,1633,1313,2199,1860,281,1807,2056,994,2847,1494,2642,192,145,1445,275,1983,1324,355,239,2827,1409 | -0.5474201594629304,0.21654186145358403,0.4269371803541035,-0.10239964490688236,0.6852623302074585,-0.24719447231895844,-0.6807859438462549,-0.04135865661767714,2.861170882369116,1.1737693798534528,2.2493125713395874,1.2073587193318431,2.739955797601633,-0.12287961106727112,-0.18472611797839597,0.255309170150584,-0.18472611797839597,-0.04135865661767714,-0.5915469880276591,0.05907835699925959,-0.37406084951540725,-0.37406084951540725,-0.6137324247371202,-0.0009917498407377972,-0.18472611797839597,-0.2263016271137345,-0.2681581692824456,-0.4169396623740783,-0.18472611797839597,-0.20547903817502652,-0.3314804483105227,-0.28919332161258265,3.4405377784263176,-0.12287961106727112,-0.20547903817502652,-0.061639706843019025,-0.4384926181619229,-0.28919332161258265,1.1400155210794878,-0.2681581692824456,-0.37406084951540725,0.13829633186814977,-0.9568488266934512,-0.14342697267853247,-0.7033054530869399,1.6141131009311325,1.9537430602483536,-0.12287961106727112,1.1569131412555997,-0.3314804483105227,-0.061639706843019025,0.8989563120030468,1.3071593288497105,-0.9099290428795153,-0.10239964490688236 | 3,053 |
Protein transmembrane transport | 10 | 25 | 2.294369 | 0.021769 | Q9NS69,Q15629,O60830,O14925,Q99442,O75381,Q99595,O95831,P31751,O43615 | Processes and pathways | GO Biological process | msigdb_gobp | 3,38,12,146,409,488,23,435,402,527 | 146,527,12,488,1778,435,613,2829,402,544,2359,2818,2187,733,2366,1105,38,986,1434,409,23,2949,3,867,1718 | 1.893169553532986,0.5573667616763491,4.210058257772574,0.612482250975132,-0.2681581692824456,0.7033333538782307,0.4457299111164649,-0.9333418075172426,0.7572541827182976,0.5388920140603658,-0.5254772864924734,-0.9099290428795153,-0.4384926181619229,0.3321505284860475,-0.5254772864924734,0.05907835699925959,3.1882814967797093,0.13829633186814977,-0.12287961106727112,0.7572541827182976,3.8165416179463243,-1.2219313118513195,4.841737850614046,0.23595476382188807,-0.2263016271137345 | 3,053 |
ER-Golgi transport | 13 | 47 | 2.293483 | 0.02182 | Q9Y6B6,P24390,Q6NUQ1,O43731,Q15436,Q15363,Q9HCU5,Q9Y282,O95197,O95070,P18085,Q9P2W9,Q9NR31 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 397,1,227,7,517,139,499,141,78,370,243,118,483 | 871,1772,612,2525,7,1935,1671,1330,370,78,780,923,2881,243,1,829,1373,926,544,674,2476,1898,1841,2089,1307,1377,881,1962,139,517,1270,227,2101,1070,1487,2288,988,723,2153,499,483,118,2338,141,1249,1933,397 | 0.21654186145358403,-0.2681581692824456,0.4457299111164649,-0.6360002154493802,4.366865380443215,-0.3314804483105227,-0.2263016271137345,-0.08198652438815046,0.8284788048032764,2.575295500784994,0.29384424374464585,0.17753878759272398,-1.0279450311062537,1.2740517609654562,5.242039873099177,0.255309170150584,-0.10239964490688236,0.17753878759272398,0.5388920140603658,0.3891883162351104,-0.5915469880276591,-0.31030054118727124,-0.28919332161258265,-0.3954626277985668,-0.061639706843019025,-0.10239964490688236,0.21654186145358403,-0.3314804483105227,1.9688079417064501,0.5757898109834075,-0.04135865661767714,1.372905949710868,-0.3954626277985668,0.07897567452569614,-0.14342697267853247,-0.48182900048661537,0.13829633186814977,0.3512189297429039,-0.4169396623740783,0.612482250975132,0.6307523498834328,2.2057255535259004,-0.5036138048570713,1.9688079417064501,-0.021142844948492293,-0.31030054118727124,0.7929611203043013 | 3,053 |
Mitochondrial nucleotide transporter subfamily | 6 | 9 | 2.292042 | 0.021903 | P12235,Q9H2D1,Q9HC21,Q9BSK2,Q70HW3,P12236 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 257,109,339,86,251,188 | 690,377,257,188,534,251,86,109,339 | 0.3702313895262678,0.8107434624970358,1.2073587193318431,1.6141131009311325,0.5573667616763491,1.240785529211058,2.5056210267947026,2.2926453330472487,0.9339209551785153 | 3,053 |
Atp synthesis coupled electron transport | 12 | 37 | 2.290364 | 0.022 | O75306,Q7KZN9,O75489,P03886,P20674,P13073,O14949,P03915,O43676,Q9UDW1,O75438,Q9H3K2 | Processes and pathways | GO Biological process | msigdb_gobp | 195,43,384,45,421,330,142,304,47,92,126,127 | 952,142,47,1177,195,126,384,434,628,1604,978,595,691,45,304,1558,614,1781,1507,330,2224,1298,1889,1831,421,3014,2134,2183,783,2413,650,43,2847,2671,127,92,1053 | 0.15794771197129795,1.9537430602483536,3.072090978975674,-0.0009917498407377972,1.566526139717696,2.1618805177312446,0.7929611203043013,0.7033333538782307,0.4269371803541035,-0.20547903817502652,0.13829633186814977,0.464468695655408,0.3702313895262678,3.0850861706306985,1.0377463366595439,-0.18472611797839597,0.4457299111164649,-0.2681581692824456,-0.16404228682087726,0.9513357791761082,-0.4601221695313692,-0.061639706843019025,-0.31030054118727124,-0.28919332161258265,0.7213554512800274,-1.959204894557855,-0.4169396623740783,-0.4384926181619229,0.29384424374464585,-0.5474201594629304,0.40809011351908236,3.149741568733179,-0.9568488266934512,-0.7259104599277266,2.1325052522465455,2.4352981359162196,0.09881078799017154 | 3,053 |
Abnormality of head blood vessel | 12 | 28 | 2.286437 | 0.022229 | P16278,Q9Y4P3,Q99519,P54198,Q13510,P21964,P03886,Q9NZJ7,P03915,P07602,P10619,P17900 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 65,228,132,133,40,387,45,275,304,113,185,186 | 1987,1666,2501,45,304,571,386,113,2598,185,2260,65,186,3042,387,2601,672,1841,133,2537,40,1428,2967,1315,132,275,1769,228 | -0.35273367187282356,-0.2263016271137345,-0.6137324247371202,3.0850861706306985,1.0377463366595439,0.5017859632503069,0.7929611203043013,2.2493125713395874,-0.6807859438462549,1.6299048673842986,-0.48182900048661537,2.739955797601633,1.6299048673842986,-3.2311544845550535,0.7929611203043013,-0.6807859438462549,0.3891883162351104,-0.28919332161258265,2.0138167795559077,-0.6360002154493802,3.162609148347032,-0.12287961106727112,-1.3214527911775553,-0.061639706843019025,2.0585502205371826,1.1569131412555997,-0.24719447231895844,1.372905949710868 | 3,053 |
Hand polydactyly | 10 | 26 | 2.285068 | 0.022309 | Q15067,P54198,O43924,Q14739,Q9BXW9,Q9UBM7,Q9UHX1,O95202,O96028,Q9Y263 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 259,133,8,41,364,269,81,148,181,355 | 2928,8,558,148,181,2815,387,2137,1841,133,647,677,758,1193,41,1850,259,2967,1315,2764,364,2973,269,81,1546,355 | -1.1484159978357622,4.344641601575348,0.5203652040028177,1.893169553532986,1.645661682349741,-0.9099290428795153,0.7929611203043013,-0.4169396623740783,-0.28919332161258265,2.0138167795559077,0.40809011351908236,0.3891883162351104,0.31302577253021713,-0.0009917498407377972,3.162609148347032,-0.28919332161258265,1.2073587193318431,-1.3214527911775553,-0.061639706843019025,-0.8172019719548473,0.8638097235543348,-1.37187830834249,1.1737693798534528,2.5614117640389127,-0.16404228682087726,0.8989563120030468 | 3,053 |
Metal ion homeostasis | 26 | 78 | 2.283252 | 0.022416 | Q9Y5X3,O76024,P05023,O95202,P09601,P30519,Q9Y487,Q96PU5,Q7L0J3,Q96TC7,Q14344,Q8NEW0,Q96A33,O60826,O43819,P16615,Q8N511,Q15904,Q8NE86,P54709,Q9HC07,Q8NE01,P20020,Q9HD20,P62942,P0DP25 | Processes and pathways | GO Biological process | msigdb_gobp | 131,256,264,148,22,25,156,286,166,428,564,49,306,558,556,436,58,318,452,577,196,458,331,211,98,361 | 2345,1214,556,2749,558,1369,627,2623,256,148,1993,1606,1938,1455,264,847,1055,2598,2433,2353,1506,22,361,1997,1459,436,2312,331,2076,826,2702,25,1999,2472,1095,674,1375,577,1010,1470,1344,98,1129,588,757,2365,1157,1385,564,1389,1695,318,886,2284,166,1435,1110,58,458,452,49,306,1437,286,428,1494,2154,1244,2671,1118,196,211,3050,796,1546,156,1409,131 | -0.5254772864924734,-0.021142844948492293,0.5203652040028177,-0.8172019719548473,0.5203652040028177,-0.10239964490688236,0.4269371803541035,-0.7033054530869399,1.2073587193318431,1.893169553532986,-0.35273367187282356,-0.20547903817502652,-0.3314804483105227,-0.14342697267853247,1.1905844892407613,0.23595476382188807,0.07897567452569614,-0.6807859438462549,-0.5694431482641074,-0.5254772864924734,-0.16404228682087726,3.828386645902461,0.8638097235543348,-0.35273367187282356,-0.14342697267853247,0.7033333538782307,-0.5036138048570713,0.9513357791761082,-0.3954626277985668,0.255309170150584,-0.7713802427604488,3.673048611757954,-0.35273367187282356,-0.5915469880276591,0.05907835699925959,0.3891883162351104,-0.10239964490688236,0.5017859632503069,0.11858418117435018,-0.14342697267853247,-0.08198652438815046,2.378562703431359,0.039118345533642226,0.4831539193642934,0.31302577253021713,-0.5254772864924734,0.019095144049973707,-0.10239964490688236,0.5203652040028177,-0.10239964490688236,-0.2263016271137345,0.9860318695770233,0.21654186145358403,-0.48182900048661537,1.7394792650550464,-0.12287961106727112,0.05907835699925959,2.834398419466517,0.6671420469276572,0.6852623302074585,3.072090978975674,1.0377463366595439,-0.12287961106727112,1.1060951140545585,0.7213554512800274,-0.14342697267853247,-0.4169396623740783,-0.021142844948492293,-0.7259104599277266,0.05907835699925959,1.566526139717696,1.4703817232301912,-4.569411343591455,0.29384424374464585,-0.16404228682087726,1.8167337774526302,-0.10239964490688236,2.0882215813866165 | 3,053 |
Synaptic vesicle membrane | 8 | 15 | 2.27962 | 0.02263 | O15126,Q7L0J3,O76024,P0DP25,P20020,O43760,O60499,P61020 | Localization | GO Cellular component | msigdb_gocc | 501,166,256,361,331,555,157,503 | 843,501,555,157,256,629,1559,361,331,1945,1098,503,934,166,1043 | 0.23595476382188807,0.5941615220565629,0.5203652040028177,1.8013490730391473,1.2073587193318431,0.4269371803541035,-0.18472611797839597,0.8638097235543348,0.9513357791761082,-0.3314804483105227,0.05907835699925959,0.5941615220565629,0.17753878759272398,1.7394792650550464,0.09881078799017154 | 3,053 |
Cardiac muscle contraction | 9 | 18 | 2.277662 | 0.022747 | P54709,P22695,P05023,P20674,P13073,O14949,P14406,P16615,Q9UDW1 | Processes and pathways | KEGG Pathways | msigdb_kegg | 577,324,264,421,330,142,85,436,92 | 142,691,264,2223,614,1458,1507,330,85,1298,1889,436,421,324,828,577,1704,92 | 1.9537430602483536,0.3702313895262678,1.1905844892407613,-0.4601221695313692,0.4457299111164649,-0.14342697267853247,-0.16404228682087726,0.9513357791761082,2.5056210267947026,-0.061639706843019025,-0.31030054118727124,0.7033333538782307,0.7213554512800274,0.9687059891173524,0.255309170150584,0.5017859632503069,-0.2263016271137345,2.4352981359162196 | 3,053 |
mitochondria | 6 | 10 | 2.263763 | 0.023589 | P21796,P45880,Q8IWA4,Q9NVH1,Q9Y277,Q9NR31 | Localization | OpenCell Localization | opencell_localization | 2,15,407,443,245,483 | 1778,2,15,2370,1105,407,540,483,443,245 | -0.2681581692824456,4.914940523522634,4.096236762872413,-0.5254772864924734,0.05907835699925959,0.7572541827182976,0.5573667616763491,0.6307523498834328,0.7033333538782307,1.2740517609654562 | 3,053 |
Aplasia hypoplasia involving the vertebral column | 7 | 15 | 2.253099 | 0.024253 | P16278,Q6NUQ1,Q14739,Q8TAA9,Q96HY6,Q7RTS9,O95831 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 65,227,41,108,400,354,435 | 1987,2431,435,454,596,752,65,1680,1738,41,2280,227,354,108,400 | -0.35273367187282356,-0.5694431482641074,0.7033333538782307,0.6671420469276572,0.464468695655408,0.31302577253021713,2.739955797601633,-0.2263016271137345,-0.24719447231895844,3.162609148347032,-0.48182900048661537,1.372905949710868,0.8989563120030468,2.2926453330472487,0.7751314656744809 | 3,053 |
Nadh dehydrogenase complex | 9 | 23 | 2.251085 | 0.02438 | O75306,Q9P0J0,O75489,P03886,Q86Y39,P03915,O43676,Q96CU9,O75438 | Localization | GO Cellular component | msigdb_gocc | 195,203,384,45,204,304,47,281,126 | 952,47,1177,195,126,384,434,628,1604,978,595,45,304,1831,3014,2183,783,2413,650,204,281,203,1053 | 0.15794771197129795,3.072090978975674,-0.0009917498407377972,1.566526139717696,2.1618805177312446,0.7929611203043013,0.7033333538782307,0.4269371803541035,-0.20547903817502652,0.13829633186814977,0.464468695655408,3.0850861706306985,1.0377463366595439,-0.28919332161258265,-1.959204894557855,-0.4384926181619229,0.29384424374464585,-0.5474201594629304,0.40809011351908236,1.502575541135129,1.1400155210794878,1.5186175105719402,0.09881078799017154 | 3,053 |
Lipid transporter activity | 13 | 20 | 2.250743 | 0.024402 | Q00169,P08183,Q4KMQ2,P04114,P11166,O15118,Q9BZF1,Q9NV96,P61916,P17900,P48739,Q9H2C2,Q14849 | Functions | GO Molecular function | msigdb_gomf | 415,349,296,571,639,51,705,541,308,186,529,192,30 | 1250,51,571,349,639,186,1832,694,529,308,415,2857,30,296,2686,1284,2059,705,192,541 | -0.04135865661767714,3.0329755799706857,0.5017859632503069,0.8989563120030468,0.40809011351908236,1.6299048673842986,-0.28919332161258265,0.3702313895262678,0.5573667616763491,1.0205517659257686,0.7393289521585672,-0.9804510545643588,3.428112577652922,1.0720060894912629,-0.7486017803237077,-0.04135865661767714,-0.37406084951540725,0.3702313895262678,1.6141131009311325,0.5573667616763491 | 3,053 |
MFS transporter superfamily [IPR036259] | 6 | 11 | 2.246569 | 0.024668 | Q8NHS3,Q7L0J3,P41440,P53985,Q96ES6,O00400 | Sequence | InterPro Superfamily | interpro_homologous_superfamily | 37,166,362,403,91,154 | 154,639,875,362,403,406,2859,166,37,91,1023 | 1.8167337774526302,0.40809011351908236,0.21654186145358403,0.8638097235543348,0.7572541827182976,0.7572541827182976,-0.9804510545643588,1.7394792650550464,3.2010864353849686,2.4352981359162196,0.11858418117435018 | 3,053 |
Cytochrome complex | 6 | 16 | 2.24282 | 0.024908 | P22695,Q7KZN9,P13073,O14949,P14406,Q9UDW1 | Localization | GO Cellular component | msigdb_gocc | 324,43,330,142,85,92 | 952,142,691,614,1458,1507,330,85,1298,1889,421,324,828,43,92,2907 | 0.15794771197129795,1.9537430602483536,0.3702313895262678,0.4457299111164649,-0.14342697267853247,-0.16404228682087726,0.9513357791761082,2.5056210267947026,-0.061639706843019025,-0.31030054118727124,0.7213554512800274,0.9687059891173524,0.255309170150584,3.149741568733179,2.4352981359162196,-1.0758316877354026 | 3,053 |
EF-hand domain [IPR002048] | 11 | 41 | 2.2425 | 0.024929 | O43852,Q9Y680,P41208,P80303,O95202,Q96AY3,Q02818,O75071,Q9UJS0,O95302,Q9NWM8 | Sequence | InterPro Domain | interpro_domain | 346,9,233,13,148,338,351,278,151,28,321 | 1452,346,278,896,819,148,28,1145,1505,361,1415,2830,1004,2974,1999,2930,233,599,1341,13,351,1579,603,1797,2195,534,1197,1700,1110,741,338,2824,1494,1865,1117,463,321,2614,151,2617,9 | -0.14342697267853247,0.8989563120030468,1.1400155210794878,0.1970700191478118,0.255309170150584,1.893169553532986,3.4529437672196814,0.019095144049973707,-0.16404228682087726,0.8638097235543348,-0.12287961106727112,-0.9333418075172426,0.11858418117435018,-1.397261622755791,-0.35273367187282356,-1.1484159978357622,1.3236542021070108,0.464468695655408,-0.08198652438815046,4.18741722715009,0.8989563120030468,-0.18472611797839597,0.464468695655408,-0.2681581692824456,-0.4384926181619229,0.5573667616763491,-0.0009917498407377972,-0.2263016271137345,0.05907835699925959,0.3321505284860475,0.9339209551785153,-0.9099290428795153,-0.14342697267853247,-0.28919332161258265,0.05907835699925959,0.6671420469276572,0.9860318695770233,-0.6807859438462549,1.8626921049716938,-0.6807859438462549,4.322359392501917 | 3,053 |
Muscle abnormality related to mitochondrial dysfunction | 9 | 33 | 2.238577 | 0.025183 | O75306,Q9UBX3,P12235,P03886,Q86Y39,O43676,Q15526,Q96CU9,Q9Y2R0 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 195,36,257,45,204,47,244,281,57 | 952,47,528,1177,195,384,595,691,45,304,257,1831,3014,1467,2183,1306,2270,244,549,204,1592,281,1650,1442,2798,2671,771,2522,36,57,895,2344,1053 | 0.15794771197129795,3.072090978975674,0.5573667616763491,-0.0009917498407377972,1.566526139717696,0.7929611203043013,0.464468695655408,0.3702313895262678,3.0850861706306985,1.0377463366595439,1.2073587193318431,-0.28919332161258265,-1.959204894557855,-0.14342697267853247,-0.4384926181619229,-0.061639706843019025,-0.48182900048661537,1.2740517609654562,0.5388920140603658,1.502575541135129,-0.18472611797839597,1.1400155210794878,-0.20547903817502652,-0.12287961106727112,-0.8633825363003653,-0.7259104599277266,0.31302577253021713,-0.6137324247371202,3.213870662525028,2.861170882369116,0.21654186145358403,-0.5036138048570713,0.09881078799017154 | 3,053 |
Protein targeting to mitochondrion | 10 | 42 | 2.236469 | 0.025321 | Q8N4H5,Q9NS69,Q99797,Q5JRX3,Q9P0J0,O60830,O14925,Q99595,Q9Y512,O14737 | Processes and pathways | GO Biological process | msigdb_gobp | 64,3,392,164,203,12,146,23,382,252 | 252,146,872,527,12,2128,1778,665,1086,1555,435,613,981,2829,1891,2265,926,756,674,1687,1520,677,1105,2095,986,549,164,2608,64,1804,1397,23,392,811,2949,3,203,1247,747,2121,382,2255 | 1.2240923176202834,1.893169553532986,0.21654186145358403,0.5573667616763491,4.210058257772574,-0.4169396623740783,-0.2681581692824456,0.3891883162351104,0.05907835699925959,-0.18472611797839597,0.7033333538782307,0.4457299111164649,0.13829633186814977,-0.9333418075172426,-0.31030054118727124,-0.48182900048661537,0.17753878759272398,0.31302577253021713,0.3891883162351104,-0.2263016271137345,-0.16404228682087726,0.3891883162351104,0.05907835699925959,-0.3954626277985668,0.13829633186814977,0.5388920140603658,1.7704807226942911,-0.6807859438462549,2.7535188063677927,-0.2681581692824456,-0.10239964490688236,3.8165416179463243,0.7929611203043013,0.2746055190128614,-1.2219313118513195,4.841737850614046,1.5186175105719402,-0.021142844948492293,0.3321505284860475,-0.3954626277985668,0.8107434624970358,-0.4601221695313692 | 3,053 |
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