term stringlengths 2 121 | overlap int64 6 281 | setsize int64 7 499 | score float64 1.96 10.6 | pval float64 0 0.05 | edge stringlengths 41 1.97k | type stringclasses 5 values | subtype stringclasses 24 values | subtype_key stringclasses 24 values | edge_idxs stringlengths 11 1.17k | ann_idxs stringlengths 19 2.31k | ann_vals stringlengths 124 9.94k | sig_size int64 2.2k 3.73k |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Abnormal chorioretinal morphology | 14 | 30 | 2.407749 | 0.016051 | Q01082,P04439,P40855,O60826,Q9Y5Y5,Q9H9S5,O75381,P31749,Q5XKP0,P50542,P53701,P49815,Q8IY17,Q8NAT1 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 540,192,256,600,301,75,486,269,697,524,316,663,411,390 | 897,709,2596,600,486,2014,3191,192,269,1185,256,1545,1259,663,524,1965,316,1442,540,2085,1001,697,2814,411,390,1424,75,1173,301,2349 | 0.40352030450058385,0.5865431038553878,-0.6292368396202702,0.7342899684920763,0.8964216526892619,-0.3043485498283727,-1.173329637849102,1.6623656284021715,1.3707265386892524,0.18360351475980163,1.3862392263267762,-0.04043100103272851,0.13227671324131024,0.66884230281273,0.8480022389189762,-0.2688116827850815,1.23026980961867,0.028954594033709185,0.8318208221873443,-0.3399951175936339,0.3194104967216977,0.6195286455637697,-0.7766800572431602,1.0405739895843595,1.0723863455217324,0.04623753210788857,2.4581284970631354,0.20066360371072753,1.2772585855164569,-0.4656361884453895 | 3,381 |
transporter | 22 | 58 | 2.392596 | 0.01673 | O60830,Q99595,Q9HD45,Q92973,P54105,Q8N1F7,Q9C0E2,O00410,Q96P70,Q9UJZ1,O43681,O60684,O43772,Q7Z3B4,Q92544,Q8NFH4,Q9H2V7,Q8N8Q8,Q99805,Q9H2D1,P53985,Q567V2 | Functions | Panther Protein class | panther_protein_class | 0,1,273,667,280,548,284,658,418,683,536,550,296,186,705,327,473,341,492,103,236,119 | 658,1277,1357,2667,2668,2009,1255,536,296,3178,550,0,2013,1638,1963,1493,2159,2078,3125,998,2047,1842,2286,236,280,1240,1241,3146,886,1650,980,119,3371,186,548,341,327,2059,730,705,667,2179,418,1428,1,492,1509,816,284,103,473,2895,273,875,2718,683,1983,2349 | 0.66884230281273,0.11511859996624757,0.06349529754497407,-0.6843010420962635,-0.6843010420962635,-0.3043485498283727,0.13227671324131024,0.8318208221873443,1.2772585855164569,-1.154111245668569,0.8156184711857695,5.073603072328636,-0.3043485498283727,-0.09273974181183568,-0.2688116827850815,-0.0056872218402178,-0.37575235994719464,-0.3399951175936339,-1.0585271123335283,0.3194104967216977,-0.3221580605870234,-0.19806322542449376,-0.44760283593211736,1.463526586756026,1.3396454442052559,0.14941016954971006,0.14941016954971006,-1.0966598820951519,0.4202725426034364,-0.09273974181183568,0.33627924845100304,2.036582146267626,-4.02669760283721,1.7229490341498392,0.8318208221873443,1.1673498693322624,1.1988483827647884,-0.3221580605870234,0.5700171494918655,0.6030469076527168,0.66884230281273,-0.37575235994719464,1.0246378972585815,0.04623753210788857,4.964986919891834,0.8964216526892619,-0.0056872218402178,0.4870521174821247,1.3396454442052559,2.2271528467595973,0.9285979925872347,-0.8324770201433779,1.3707265386892524,0.4370017529662837,-0.7027159312432755,0.6524262597868276,-0.2688116827850815,-0.4656361884453895 | 3,381 |
Macromolecule transmembrane transporter activity | 8 | 12 | 2.389097 | 0.01689 | O60830,Q99595,Q9UGP8,P49755,P51991,Q9NS69,O14925,Q15388 | Functions | GO Molecular function | msigdb_gomf | 0,1,226,538,477,5,264,465 | 264,0,1336,568,538,477,3146,675,465,1,5,226 | 1.3707265386892524,5.073603072328636,0.08072799489487778,0.7831506553954769,0.8318208221873443,0.9125200992112816,-1.0966598820951519,0.6524262597868276,0.9285979925872347,4.964986919891834,4.32249087085326,1.5250288963471914 | 3,381 |
Negative regulation of rna catabolic process | 13 | 31 | 2.379552 | 0.017334 | Q9H074,Q9H814,P67809,P35637,O60506,Q99729,Q14103,P98175,Q08J23,Q14011,Q13151,Q06787,Q92804 | Processes and pathways | GO Biological process | msigdb_gobp | 194,460,73,77,176,244,500,439,408,89,448,634,63 | 2930,176,2801,1732,2705,647,826,77,1932,73,439,2574,634,885,408,2636,448,89,500,1019,791,1420,1507,63,244,3166,194,1633,460,894,1123 | -0.8698314423424568,1.7531374146957515,-0.7766800572431602,-0.14528280773655003,-0.7027159312432755,0.6852366133893191,0.47039145099938634,2.4294663659270506,-0.25108408655359427,2.4724374570925978,0.9767091001145846,-0.610941794333371,0.7016092735780922,0.4202725426034364,1.0405739895843595,-0.6475616366576715,0.9606924188585974,2.314221925162671,0.8803025777169821,0.30251816305270063,0.5036901138602248,0.04623753210788857,-0.0056872218402178,2.628876532164271,1.4326666084227007,-1.1157765393410726,1.6623656284021715,-0.07527760638334166,0.944655407668733,0.4202725426034364,0.2347111094017979 | 3,381 |
Abnormal choroid morphology | 14 | 31 | 2.374039 | 0.017595 | Q01082,P04439,P40855,O60826,Q9Y5Y5,Q9H9S5,O75381,P31749,Q5XKP0,P50542,P53701,P49815,Q8IY17,Q8NAT1 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 540,192,256,600,301,75,486,269,697,524,316,663,411,390 | 897,709,2596,600,486,2014,3191,192,1129,269,1185,256,1545,1259,663,524,1965,316,1442,540,2085,1001,697,2814,411,390,1424,75,1173,301,2349 | 0.40352030450058385,0.5865431038553878,-0.6292368396202702,0.7342899684920763,0.8964216526892619,-0.3043485498283727,-1.173329637849102,1.6623656284021715,0.21769943580617096,1.3707265386892524,0.18360351475980163,1.3862392263267762,-0.04043100103272851,0.13227671324131024,0.66884230281273,0.8480022389189762,-0.2688116827850815,1.23026980961867,0.028954594033709185,0.8318208221873443,-0.3399951175936339,0.3194104967216977,0.6195286455637697,-0.7766800572431602,1.0405739895843595,1.0723863455217324,0.04623753210788857,2.4581284970631354,0.20066360371072753,1.2772585855164569,-0.4656361884453895 | 3,381 |
Central scotoma | 6 | 11 | 2.368521 | 0.017859 | Q9Y287,P00846,P03886,O60220,Q9H061,Q8WWV3 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 245,54,247,121,30,351 | 924,121,767,1760,54,247,2882,351,30,375,245 | 0.3699463810201887,2.0070251955300082,0.5203055281119934,-0.16284975656285822,2.727529421964283,1.417209198502823,-0.8324770201433779,1.151571535639279,3.156391655179004,1.1041194035027075,1.4326666084227007 | 3,381 |
Generalized hirsutism | 7 | 28 | 2.366962 | 0.017935 | O95155,P02545,Q03252,P31749,Q96JJ3,Q03164,O00170 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 319,4,145,269,146,174,279 | 279,2725,2353,319,4,1901,3198,1467,269,1843,174,145,2166,1996,1551,374,2134,1687,2000,146,2921,1659,1566,2246,1432,2928,821,2662 | 1.3396454442052559,-0.7211611336557268,-0.48369809024111093,1.2145686983078836,4.32249087085326,-0.233383556658795,-1.1925822871771383,0.011646378050987276,1.3707265386892524,-0.19806322542449376,1.7682059696602237,1.8732124396128473,-0.37575235994719464,-0.2865664640305207,-0.04043100103272851,1.1041194035027075,-0.3578598430231122,-0.1102279128477972,-0.2865664640305207,1.8732124396128473,-0.8511384861420023,-0.09273974181183568,-0.04043100103272851,-0.41162126510560293,0.04623753210788857,-0.8511384861420023,0.4870521174821247,-0.6659163242058336 | 3,381 |
Ensheathment of neurons | 15 | 30 | 2.366902 | 0.017938 | Q13614,Q96PU8,P31751,P10909,Q16880,P31749,Q8IXJ6,Q92542,Q8N3R9,Q7L576,P49770,Q9Y4W6,O75312,Q15058,Q9NR77 | Processes and pathways | GO Biological process | msigdb_gobp | 161,815,136,167,235,269,175,692,365,594,496,382,846,635,875 | 949,846,898,2115,167,1338,269,136,1185,1439,496,1843,1056,1287,3028,161,635,1445,235,594,175,365,692,1692,815,875,2436,2109,2411,382 | 0.3531245121268438,0.45370802586662823,0.40352030450058385,-0.3578598430231122,1.7832575080155384,0.08072799489487778,1.3707265386892524,1.9179645577932507,0.18360351475980163,0.028954594033709185,0.8803025777169821,-0.19806322542449376,0.26866237124034603,0.11511859996624757,-0.9449212358676787,1.8133097539294933,0.7016092735780922,0.028954594033709185,1.4789292784634316,0.7505981648073553,1.7682059696602237,1.1199563718210412,0.6359884017355526,-0.1102279128477972,0.4870521174821247,0.4370017529662837,-0.5199080611106346,-0.3399951175936339,-0.5017886709334725,1.088262751441023 | 3,381 |
Focal segmental glomerulosclerosis | 9 | 24 | 2.356431 | 0.018451 | Q8NFH4,Q9BW27,O95470,Q14108,O43707,P03886,O75431,Q8N1F7,P00403 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 327,459,520,554,332,247,88,548,380 | 332,88,520,380,247,1409,1241,3146,886,1414,554,690,1588,2365,548,327,1447,2267,1424,1691,459,2215,1329,1793 | 1.1831087956745996,2.314221925162671,0.8480022389189762,1.088262751441023,1.417209198502823,0.04623753210788857,0.14941016954971006,-1.0966598820951519,0.4202725426034364,0.04623753210788857,0.8156184711857695,0.6359884017355526,-0.057841396040278596,-0.48369809024111093,0.8318208221873443,1.1988483827647884,0.028954594033709185,-0.4295979040509883,0.04623753210788857,-0.1102279128477972,0.944655407668733,-0.39367279234365044,0.09793572799284321,-0.16284975656285822 | 3,381 |
Abnormality of the phalanges of the toes | 6 | 22 | 2.353154 | 0.018615 | Q7LGA3,P02545,Q6DKJ4,Q8WVQ1,O75431,O75844 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 193,4,421,532,88,159 | 897,88,159,4,1865,1078,3023,1496,1808,575,421,3173,193,532,1535,1269,1953,1271,2620,1397,2151,1570 | 0.40352030450058385,2.314221925162671,1.8133097539294933,4.32249087085326,-0.21570997527597668,0.2516987221968761,-0.9449212358676787,-0.0056872218402178,-0.18044319095933925,0.7831506553954769,1.0086817664528895,-1.1349269369210717,1.6623656284021715,0.8480022389189762,-0.02304631237539939,0.13227671324131024,-0.25108408655359427,0.13227671324131024,-0.6292368396202702,0.06349529754497407,-0.3578598430231122,-0.04043100103272851 | 3,381 |
Selective autophagy | 8 | 31 | 2.338086 | 0.019383 | Q8N4H5,Q9NS69,P21796,Q13501,P50542,Q15388,P08670,Q8IWA4 | Processes and pathways | Reactome Pathways | msigdb_reactome | 33,5,199,429,524,465,23,450 | 1605,1095,1336,568,1466,23,1211,2227,199,524,1342,1313,1314,1937,2083,1318,902,429,1871,1811,2811,465,450,33,3165,2239,3272,1725,2407,5,1461 | -0.07527760638334166,0.2347111094017979,0.08072799489487778,0.7831506553954769,0.011646378050987276,3.278550011009387,0.16651906993514767,-0.41162126510560293,1.6319696996489776,0.8480022389189762,0.08072799489487778,0.09793572799284321,0.09793572799284321,-0.25108408655359427,-0.3399951175936339,0.09793572799284321,0.40352030450058385,0.9927055249531092,-0.21570997527597668,-0.18044319095933925,-0.7766800572431602,0.9285979925872347,0.9606924188585974,3.046937180331755,-1.1157765393410726,-0.41162126510560293,-1.3870322116472107,-0.12774223079298147,-0.5017886709334725,4.32249087085326,0.028954594033709185 | 3,381 |
Serositis | 8 | 22 | 2.337963 | 0.019389 | Q9NZ08,Q8NFH4,P01889,Q9BW27,O15460,O43707,P14174,Q8N1F7 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 289,327,442,459,104,332,239,548 | 104,332,442,239,3023,2326,1409,1241,886,1414,690,1588,548,327,1447,2267,1691,459,2215,289,1329,1793 | 2.1834104512228016,1.1831087956745996,0.9606924188585974,1.4481057172341323,-0.9449212358676787,-0.4656361884453895,0.04623753210788857,0.14941016954971006,0.4202725426034364,0.04623753210788857,0.6359884017355526,-0.057841396040278596,0.8318208221873443,1.1988483827647884,0.028954594033709185,-0.4295979040509883,-0.1102279128477972,0.944655407668733,-0.39367279234365044,1.3084896317780137,0.09793572799284321,-0.16284975656285822 | 3,381 |
Dental crowding | 7 | 26 | 2.336837 | 0.019448 | P02545,P36543,Q96A33,O75431,Q01105,P06753,O75844 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 4,324,458,88,58,218,159 | 88,2624,159,4,218,1734,1544,2503,324,1259,2163,58,2085,2021,1996,478,1164,1084,2814,2002,2767,458,2921,1270,2524,2151 | 2.314221925162671,-0.6475616366576715,1.8133097539294933,4.32249087085326,1.5403594847627644,-0.14528280773655003,-0.04043100103272851,-0.5744404092580189,1.1988483827647884,0.13227671324131024,-0.37575235994719464,2.6712408389899127,-0.3399951175936339,-0.3043485498283727,-0.2865664640305207,0.9125200992112816,0.20066360371072753,0.2516987221968761,-0.7766800572431602,-0.2865664640305207,-0.7396367924488996,0.944655407668733,-0.8511384861420023,0.13227671324131024,-0.5744404092580189,-0.3578598430231122 | 3,381 |
Photophobia | 15 | 40 | 2.33553 | 0.019516 | Q9NZ08,P04439,Q86YV9,Q6P4Q7,O43172,P51648,P07602,Q15555,Q9Y287,Q8IY17,Q9NZJ7,O60220,Q9BV73,Q9Y4W6,Q8WWV3 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 289,192,326,354,383,333,81,374,245,411,377,121,283,382,351 | 2932,383,2442,1795,121,2318,2014,3123,442,1577,192,81,2599,2498,1338,2226,1581,2630,2729,1545,3237,2326,2568,333,2054,2261,374,3149,354,326,411,351,855,1879,549,283,289,377,245,382 | -0.8698314423424568,1.0723863455217324,-0.5380563923449663,-0.18044319095933925,2.0070251955300082,-0.4656361884453895,-0.3043485498283727,-1.0585271123335283,0.9606924188585974,-0.057841396040278596,1.6623656284021715,2.4007449963234015,-0.6292368396202702,-0.5744404092580189,0.08072799489487778,-0.41162126510560293,-0.057841396040278596,-0.6475616366576715,-0.7211611336557268,-0.04043100103272851,-1.3088274981671097,-0.4656361884453895,-0.610941794333371,1.1831087956745996,-0.3221580605870234,-0.4295979040509883,1.1041194035027075,-1.0966598820951519,1.1357737261005323,1.1988483827647884,1.0405739895843595,1.151571535639279,0.45370802586662823,-0.21570997527597668,0.8318208221873443,1.3396454442052559,1.3084896317780137,1.1041194035027075,1.4326666084227007,1.088262751441023 | 3,381 |
Intermediate filament | 8 | 21 | 2.330325 | 0.019789 | P02545,P48681,P07196,P07197,P20700,Q03252,P08670,Q16352 | Localization | GO Cellular component | msigdb_gocc | 4,196,69,42,297,145,23,251 | 1512,555,4,69,42,23,2536,3020,297,196,1743,3330,955,3358,145,1445,251,1297,3012,414,1155 | -0.02304631237539939,0.7993951082889633,4.32249087085326,2.5152764326345016,2.9089402317249307,3.278550011009387,-0.5926763630965615,-0.9449212358676787,1.2772585855164569,1.647176397021248,-0.14528280773655003,-1.8894744667105232,0.3531245121268438,-2.6376670739602184,1.8732124396128473,0.028954594033709185,1.4017334253090765,0.11511859996624757,-0.9261007824267626,1.0405739895843595,0.21769943580617096 | 3,381 |
Muscle abnormality related to mitochondrial dysfunction | 11 | 38 | 2.327402 | 0.019944 | Q9Y6M9,Q96CU9,Q8N183,Q9Y2R0,O43676,Q9UBX3,P00846,P03886,P00403,P56556,Q86Y39 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 436,14,468,48,17,178,54,247,380,125,350 | 1893,17,767,2562,1760,1863,825,847,1256,380,54,247,1309,3206,3305,1932,3285,1214,125,834,350,468,1476,2175,14,1426,944,1949,472,2768,624,1173,1891,178,48,3167,2665,436 | -0.233383556658795,3.5198547952428183,0.5203055281119934,-0.610941794333371,-0.16284975656285822,-0.21570997527597668,0.47039145099938634,0.45370802586662823,0.13227671324131024,1.088262751441023,2.727529421964283,1.417209198502823,0.09793572799284321,-1.211869368833104,-1.5451951225647298,-0.25108408655359427,-1.4460659147478525,0.16651906993514767,1.9922224857685245,0.47039145099938634,1.151571535639279,0.9285979925872347,0.011646378050987276,-0.37575235994719464,3.665405898737808,0.04623753210788857,0.3699463810201887,-0.25108408655359427,0.9285979925872347,-0.7396367924488996,0.7179603649304444,0.20066360371072753,-0.21570997527597668,1.7531374146957515,2.7975768714129026,-1.1157765393410726,-0.6659163242058336,0.9927055249531092 | 3,381 |
Sensorimotor neuropathy | 7 | 33 | 2.32738 | 0.019945 | P07196,Q9Y2R0,P07602,P00846,P03886,Q9NZJ7,P00403 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 69,48,81,54,247,377,380 | 924,2351,767,1209,927,380,54,247,911,69,81,1835,2783,3049,1079,1545,2159,2121,1374,1313,2939,1808,724,1474,1083,1386,890,1535,875,1046,377,48,382 | 0.3699463810201887,-0.48369809024111093,0.5203055281119934,0.16651906993514767,0.3699463810201887,1.088262751441023,2.727529421964283,1.417209198502823,0.3867449477923637,2.5152764326345016,2.4007449963234015,-0.19806322542449376,-0.7581430518565561,-0.9637739539367629,0.2516987221968761,-0.04043100103272851,-0.37575235994719464,-0.3578598430231122,0.06349529754497407,0.09793572799284321,-0.8698314423424568,-0.18044319095933925,0.5700171494918655,0.011646378050987276,0.2516987221968761,0.06349529754497407,0.4202725426034364,-0.02304631237539939,0.4370017529662837,0.285602152936856,1.1041194035027075,2.7975768714129026,1.088262751441023 | 3,381 |
Hydrogen ion transport | 8 | 20 | 2.32683 | 0.019974 | Q9Y487,Q93050,P36543,O75964,P56134,P61421,P00846,P06576 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 64,71,324,46,304,591,54,371 | 1576,46,54,371,1865,3068,914,756,1103,324,1673,3199,304,865,591,1038,71,1330,64,614 | -0.057841396040278596,2.7975768714129026,2.727529421964283,1.1041194035027075,-0.21570997527597668,-0.9826590952942919,0.3867449477923637,0.5368984476537072,0.2347111094017979,1.1988483827647884,-0.1102279128477972,-1.1925822871771383,1.2616146868698537,0.4370017529662837,0.7505981648073553,0.285602152936856,2.5010113820047586,0.09793572799284321,2.628876532164271,0.7342899684920763 | 3,381 |
Neuron apoptotic process | 8 | 51 | 2.321811 | 0.020243 | P50897,P07196,P05067,P31751,Q9NR28,P09601,Q96A26,Q01105 | Processes and pathways | GO Biological process | msigdb_gobp | 100,69,132,136,76,13,56,58 | 1512,846,848,1362,927,687,3273,2904,1540,132,2495,69,1708,13,3111,1797,136,1185,1130,2045,196,2326,1035,2884,100,2710,1934,1845,2940,2605,1905,1413,58,915,675,1217,2262,635,478,636,692,2431,56,2745,3272,2747,3308,2925,76,820,1459 | -0.02304631237539939,0.45370802586662823,0.45370802586662823,0.06349529754497407,0.3699463810201887,0.6359884017355526,-1.4066735867376003,-0.8511384861420023,-0.04043100103272851,1.9328488984240189,-0.5744404092580189,2.5152764326345016,-0.12774223079298147,3.783448138156203,-1.0395106651639698,-0.18044319095933925,1.9179645577932507,0.18360351475980163,0.21769943580617096,-0.3221580605870234,1.647176397021248,-0.4656361884453895,0.285602152936856,-0.8324770201433779,2.2271528467595973,-0.7027159312432755,-0.25108408655359427,-0.19806322542449376,-0.8698314423424568,-0.6292368396202702,-0.233383556658795,0.04623753210788857,2.6712408389899127,0.3867449477923637,0.6524262597868276,0.16651906993514767,-0.4295979040509883,0.7016092735780922,0.9125200992112816,0.7016092735780922,0.6359884017355526,-0.5199080611106346,2.727529421964283,-0.7211611336557268,-1.3870322116472107,-0.7211611336557268,-1.585110386151516,-0.8511384861420023,2.443804814473239,0.4870521174821247,0.028954594033709185 | 3,381 |
Endopeptidase activity | 28 | 68 | 2.320472 | 0.020315 | P20618,P28074,P22695,Q99797,Q92905,P67812,Q9Y4E8,P42892,P49721,O75844,Q9NZ08,O43464,Q6P179,Q92542,O14773,Q5JRX3,Q96RU2,Q4J6C6,Q96K76,P78536,Q99436,P28070,Q9BYT8,P13798,P28072,Q8TCT9,Q16740,Q9Y4W6 | Functions | GO Molecular function | msigdb_gomf | 130,513,512,7,777,137,274,140,399,159,289,162,163,692,318,197,718,715,342,722,610,232,368,615,362,504,248,382 | 318,1180,162,879,1181,159,1929,1899,3048,950,615,2194,3275,130,512,2566,232,362,513,2282,1238,2019,140,1841,2859,1744,399,1341,2329,1843,3183,1770,137,722,1001,1139,2261,2547,3112,1141,248,715,197,903,163,2171,1167,1224,504,692,2002,777,2654,2485,342,718,798,610,2747,7,2748,1246,368,289,274,1069,382,843 | 1.2145686983078836,0.18360351475980163,1.7982920845921333,0.4202725426034364,0.18360351475980163,1.8133097539294933,-0.25108408655359427,-0.233383556658795,-0.9637739539367629,0.3531245121268438,0.7179603649304444,-0.39367279234365044,-1.4066735867376003,1.9477168099260758,0.8641627985338416,-0.610941794333371,1.4943138534902085,1.1199563718210412,0.8641627985338416,-0.44760283593211736,0.14941016954971006,-0.3043485498283727,1.9030637360185523,-0.19806322542449376,-0.8138468931391319,-0.14528280773655003,1.0564901152174682,0.08072799489487778,-0.4656361884453895,-0.19806322542449376,-1.154111245668569,-0.16284975656285822,1.9179645577932507,0.5700171494918655,0.3194104967216977,0.21769943580617096,-0.4295979040509883,-0.5926763630965615,-1.0395106651639698,0.21769943580617096,1.417209198502823,0.5865431038553878,1.647176397021248,0.40352030450058385,1.7982920845921333,-0.37575235994719464,0.20066360371072753,0.16651906993514767,0.8803025777169821,0.6359884017355526,-0.2865664640305207,0.5203055281119934,-0.6659163242058336,-0.5562337972034157,1.1673498693322624,0.5865431038553878,0.5036901138602248,0.7342899684920763,-0.7211611336557268,4.144909340259825,-0.7211611336557268,0.14941016954971006,1.1199563718210412,1.3084896317780137,1.3707265386892524,0.26866237124034603,1.088262751441023,0.47039145099938634 | 3,381 |
Abnormal pleura morphology | 9 | 23 | 2.320184 | 0.020331 | Q9NZ08,P01889,Q9UID3,P36543,O15460,Q8NCH0,P14174,Q14739,P49815 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 289,442,626,324,104,80,239,592,663 | 104,2380,442,661,239,1369,2540,324,2326,663,1965,1807,3101,1139,1586,592,1687,80,1350,1199,289,626,2109 | 2.1834104512228016,-0.5017886709334725,0.9606924188585974,0.66884230281273,1.4481057172341323,0.06349529754497407,-0.5926763630965615,1.1988483827647884,-0.4656361884453895,0.66884230281273,-0.2688116827850815,-0.18044319095933925,-1.0205272889889005,0.21769943580617096,-0.057841396040278596,0.7505981648073553,-0.1102279128477972,2.4151131078172017,0.08072799489487778,0.18360351475980163,1.3084896317780137,0.7179603649304444,-0.3399951175936339 | 3,381 |
metalloprotease | 9 | 28 | 2.319972 | 0.020342 | Q9NZ08,Q6P179,Q5JRX3,Q99797,Q9BYT8,P42892,Q9UIQ6,P55786,O75844 | Functions | Panther Protein class | panther_protein_class | 289,163,197,7,368,140,111,113,159 | 879,1181,159,1362,991,3198,2194,512,3210,1491,140,2329,3361,113,1001,2261,197,163,2023,1296,798,7,368,1887,2064,289,111,382 | 0.4202725426034364,0.18360351475980163,1.8133097539294933,0.06349529754497407,0.3194104967216977,-1.1925822871771383,-0.39367279234365044,0.8641627985338416,-1.2311910594807025,-0.0056872218402178,1.9030637360185523,-0.4656361884453895,-2.7494110373977514,2.1248688461959304,0.3194104967216977,-0.4295979040509883,1.647176397021248,1.7982920845921333,-0.3043485498283727,0.11511859996624757,0.5036901138602248,4.144909340259825,1.1199563718210412,-0.21570997527597668,-0.3221580605870234,1.3084896317780137,2.154171009391761,1.088262751441023 | 3,381 |
Ire1alpha activates chaperones | 12 | 26 | 2.310791 | 0.020844 | Q9NWM8,P02545,Q9Y5M8,Q14554,O43731,P61421,Q13217,P35611,Q14203,O95070,P43307,O14773 | Processes and pathways | Reactome Pathways | msigdb_reactome | 66,4,822,743,92,591,724,495,409,566,29,318 | 318,92,848,2156,566,4,1278,2256,495,29,2199,1934,591,2942,724,409,743,2263,2234,1195,2268,2305,66,2313,1459,822 | 1.2145686983078836,2.299748594818239,0.45370802586662823,-0.37575235994719464,0.7831506553954769,4.32249087085326,0.11511859996624757,-0.4295979040509883,0.8803025777169821,3.156391655179004,-0.39367279234365044,-0.25108408655359427,0.7505981648073553,-0.8698314423424568,0.5700171494918655,1.0405739895843595,0.5534689593446168,-0.4295979040509883,-0.41162126510560293,0.18360351475980163,-0.4295979040509883,-0.44760283593211736,2.60056263958199,-0.44760283593211736,0.028954594033709185,0.4870521174821247 | 3,381 |
Organelle membrane fusion | 10 | 33 | 2.302753 | 0.021293 | P04083,O43752,O95721,P31751,O15400,Q13277,O95249,Q13190,Q9BZG1,O60499 | Processes and pathways | GO Biological process | msigdb_gobp | 415,98,254,136,331,306,147,373,220,311 | 2931,331,98,1894,311,925,1761,147,254,415,2042,1734,136,2200,2452,1239,2422,714,373,306,773,983,1063,450,2516,889,2743,220,2489,1329,2067,1703,1457 | -0.8698314423424568,1.1831087956745996,2.2417026963732325,-0.233383556658795,1.23026980961867,0.3699463810201887,-0.16284975656285822,1.8582618595817693,1.3862392263267762,1.0246378972585815,-0.3221580605870234,-0.14528280773655003,1.9179645577932507,-0.39367279234365044,-0.5380563923449663,0.14941016954971006,-0.5199080611106346,0.5865431038553878,1.1041194035027075,1.2459517836247969,0.5203055281119934,0.33627924845100304,0.26866237124034603,0.9606924188585974,-0.5744404092580189,0.4202725426034364,-0.7211611336557268,1.5403594847627644,-0.5562337972034157,0.09793572799284321,-0.3221580605870234,-0.1102279128477972,0.028954594033709185 | 3,381 |
Peripheral axonal neuropathy | 15 | 52 | 2.30108 | 0.021387 | Q8IV08,P07196,Q9NVI7,Q96BR5,P22626,P07602,Q9BPX6,P00403,P00846,Q9H0B6,P03886,Q9NZJ7,Q8IY17,Q9Y4W6,Q15067 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 258,69,461,231,298,81,471,380,54,158,247,377,411,382,449 | 802,2351,2596,767,2251,848,927,380,54,247,2672,69,3048,81,2074,849,1309,2226,298,2978,2567,1519,2884,514,1935,1313,1617,1082,2021,1808,1871,2811,2576,449,2812,3158,1555,2790,258,411,231,2139,1351,1426,471,2369,158,2699,461,377,382,2414 | 0.4870521174821247,-0.48369809024111093,-0.6292368396202702,0.5203055281119934,-0.4295979040509883,0.45370802586662823,0.3699463810201887,1.088262751441023,2.727529421964283,1.417209198502823,-0.6843010420962635,2.5152764326345016,-0.9637739539367629,2.4007449963234015,-0.3399951175936339,0.45370802586662823,0.09793572799284321,-0.41162126510560293,1.2772585855164569,-0.9073124362309171,-0.610941794333371,-0.02304631237539939,-0.8324770201433779,0.8641627985338416,-0.25108408655359427,0.09793572799284321,-0.07527760638334166,0.2516987221968761,-0.3043485498283727,-0.18044319095933925,-0.21570997527597668,-0.7766800572431602,-0.610941794333371,0.9606924188585974,-0.7766800572431602,-1.1157765393410726,-0.04043100103272851,-0.7581430518565561,1.3862392263267762,1.0405739895843595,1.509680372631674,-0.3578598430231122,0.08072799489487778,0.04623753210788857,0.9285979925872347,-0.48369809024111093,1.8283105702783014,-0.6843010420962635,0.944655407668733,1.1041194035027075,1.088262751441023,-0.5017886709334725 | 3,381 |
Metallopeptidase activity | 15 | 43 | 2.295614 | 0.021698 | Q9NZ08,Q6P179,Q5JRX3,Q99797,Q969V3,Q9BYT8,P42892,Q9UIQ6,P55786,P09960,O15372,P36551,Q9Y4W6,O75976,O75844 | Functions | GO Molecular function | msigdb_gomf | 289,163,197,7,457,368,140,111,113,337,378,381,382,288,159 | 1092,910,378,879,1181,159,288,1362,991,337,3198,2194,512,3210,381,140,1641,2329,3361,113,722,1001,2261,197,163,3149,1876,2023,777,457,1296,798,7,2748,368,2992,1172,1887,2795,2064,289,111,382 | 0.2347111094017979,0.3867449477923637,1.088262751441023,0.4202725426034364,0.18360351475980163,1.8133097539294933,1.3240769098404388,0.06349529754497407,0.3194104967216977,1.1673498693322624,-1.1925822871771383,-0.39367279234365044,0.8641627985338416,-1.2311910594807025,1.088262751441023,1.9030637360185523,-0.09273974181183568,-0.4656361884453895,-2.7494110373977514,2.1248688461959304,0.5700171494918655,0.3194104967216977,-0.4295979040509883,1.647176397021248,1.7982920845921333,-1.0966598820951519,-0.21570997527597668,-0.3043485498283727,0.5203055281119934,0.944655407668733,0.11511859996624757,0.5036901138602248,4.144909340259825,-0.7211611336557268,1.1199563718210412,-0.9073124362309171,0.20066360371072753,-0.21570997527597668,-0.7581430518565561,-0.3221580605870234,1.3084896317780137,2.154171009391761,1.088262751441023 | 3,381 |
Membrane fusion | 12 | 47 | 2.294928 | 0.021737 | P04083,O43752,O95721,P31751,O15400,Q9P2W9,Q13277,O95249,Q15276,Q9BZG1,O60499,Q13190 | Processes and pathways | GO Biological process | msigdb_gobp | 415,98,254,136,331,177,306,147,338,220,311,373 | 2931,924,331,1306,98,1894,311,925,1761,147,254,415,2042,1734,136,2883,2200,2452,1239,1261,2422,714,373,306,773,338,2094,983,1063,450,2516,889,2296,2743,2030,892,220,2489,2373,2275,1329,177,2898,2067,1703,1511,1457 | -0.8698314423424568,0.3699463810201887,1.1831087956745996,0.09793572799284321,2.2417026963732325,-0.233383556658795,1.23026980961867,0.3699463810201887,-0.16284975656285822,1.8582618595817693,1.3862392263267762,1.0246378972585815,-0.3221580605870234,-0.14528280773655003,1.9179645577932507,-0.8324770201433779,-0.39367279234365044,-0.5380563923449663,0.14941016954971006,0.13227671324131024,-0.5199080611106346,0.5865431038553878,1.1041194035027075,1.2459517836247969,0.5203055281119934,1.1673498693322624,-0.3399951175936339,0.33627924845100304,0.26866237124034603,0.9606924188585974,-0.5744404092580189,0.4202725426034364,-0.44760283593211736,-0.7211611336557268,-0.3043485498283727,0.4202725426034364,1.5403594847627644,-0.5562337972034157,-0.48369809024111093,-0.4295979040509883,0.09793572799284321,1.7531374146957515,-0.8324770201433779,-0.3221580605870234,-0.1102279128477972,-0.0056872218402178,0.028954594033709185 | 3,381 |
Protein transmembrane transporter activity | 7 | 11 | 2.293846 | 0.021799 | O60830,Q99595,Q9UGP8,P49755,Q9NS69,O14925,Q15388 | Functions | GO Molecular function | msigdb_gomf | 0,1,226,538,5,264,465 | 264,0,1336,568,538,3146,675,465,1,5,226 | 1.3707265386892524,5.073603072328636,0.08072799489487778,0.7831506553954769,0.8318208221873443,-1.0966598820951519,0.6524262597868276,0.9285979925872347,4.964986919891834,4.32249087085326,1.5250288963471914 | 3,381 |
Schizophrenia | 7 | 22 | 2.293607 | 0.021813 | P54198,P21964,Q9BUK6,P07602,O00192,Q9NZJ7,Q9BQE5 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 539,12,472,81,370,377,24 | 370,2350,536,2828,848,687,81,994,12,2677,539,1647,1719,2742,1880,2767,1198,24,472,1270,1273,377 | 1.1041194035027075,-0.48369809024111093,0.8318208221873443,-0.7952479551162744,0.45370802586662823,0.6359884017355526,2.4007449963234015,0.3194104967216977,3.8486291662636134,-0.6843010420962635,0.8318208221873443,-0.09273974181183568,-0.12774223079298147,-0.7211611336557268,-0.21570997527597668,-0.7396367924488996,0.18360351475980163,3.278550011009387,0.9285979925872347,0.13227671324131024,0.13227671324131024,1.1041194035027075 | 3,381 |
Horizontal nystagmus | 6 | 24 | 2.291649 | 0.021926 | P20700,Q969F9,P07602,P00846,Q9H061,O14773 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 297,211,81,54,30,318 | 2932,924,318,823,767,1017,927,54,687,81,297,1493,524,2080,1935,2231,2131,2135,211,30,1046,2468,377,1456 | -0.8698314423424568,0.3699463810201887,1.2145686983078836,0.47039145099938634,0.5203055281119934,0.30251816305270063,0.3699463810201887,2.727529421964283,0.6359884017355526,2.4007449963234015,1.2772585855164569,-0.0056872218402178,0.8480022389189762,-0.3399951175936339,-0.25108408655359427,-0.41162126510560293,-0.3578598430231122,-0.3578598430231122,1.570967094546599,3.156391655179004,0.285602152936856,-0.5380563923449663,1.1041194035027075,0.028954594033709185 | 3,381 |
Golgi stack | 13 | 36 | 2.290565 | 0.021989 | Q8TBA6,Q99523,P04439,Q8NBZ7,O00461,Q9H4A5,Q8WVQ1,Q10472,Q9H4A6,Q08379,O95249,Q14789,Q9BZG1 | Localization | GO Cellular component | msigdb_gocc | 322,225,192,68,37,198,532,334,206,617,147,593,220 | 37,925,147,192,951,2883,1107,1315,1110,2085,1500,617,978,334,1001,593,2510,3170,2292,68,322,940,532,1598,225,3304,668,1246,220,198,206,1665,1511,1537,3078,1275 | 2.9642982028262903,0.3699463810201887,1.8582618595817693,1.6623656284021715,0.3531245121268438,-0.8324770201433779,0.2347111094017979,0.09793572799284321,0.2347111094017979,-0.3399951175936339,-0.0056872218402178,0.7179603649304444,0.33627924845100304,1.1831087956745996,0.3194104967216977,0.7505981648073553,-0.5744404092580189,-1.1349269369210717,-0.44760283593211736,2.5579844473774735,1.2145686983078836,0.3699463810201887,0.8480022389189762,-0.057841396040278596,1.5250288963471914,-1.5252943800979837,0.66884230281273,0.14941016954971006,1.5403594847627644,1.647176397021248,1.5862442345229415,-0.09273974181183568,-0.0056872218402178,-0.02304631237539939,-0.9826590952942919,0.13227671324131024 | 3,381 |
Cns demyelination | 7 | 13 | 2.287286 | 0.022179 | Q9H9P8,P40855,Q9NR50,P51648,P07602,Q9NZJ7,Q15067 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 65,256,435,333,81,377,449 | 81,256,1932,496,333,1287,1528,449,2947,65,435,377,2436 | 2.4007449963234015,1.3862392263267762,-0.25108408655359427,0.8803025777169821,1.1831087956745996,0.11511859996624757,-0.02304631237539939,0.9606924188585974,-0.8698314423424568,2.6147267152556526,0.9927055249531092,1.1041194035027075,-0.5199080611106346 | 3,381 |
ATP synthase | 7 | 21 | 2.285854 | 0.022263 | Q9Y487,Q93050,O75964,P56134,P61421,P00846,P06576 | Functions | Panther Protein class | panther_protein_class | 64,71,46,304,591,54,371 | 1576,46,54,371,1865,3068,914,756,1103,1673,3199,304,865,591,1038,1293,71,1197,1330,64,614 | -0.057841396040278596,2.7975768714129026,2.727529421964283,1.1041194035027075,-0.21570997527597668,-0.9826590952942919,0.3867449477923637,0.5368984476537072,0.2347111094017979,-0.1102279128477972,-1.1925822871771383,1.2616146868698537,0.4370017529662837,0.7505981648073553,0.285602152936856,0.11511859996624757,2.5010113820047586,0.18360351475980163,0.09793572799284321,2.628876532164271,0.7342899684920763 | 3,381 |
Respiratory electron transport | 20 | 58 | 2.284155 | 0.022362 | P22695,O95298,O43676,O75880,Q16718,Q9UDW1,O14548,Q9BQ95,O43674,Q9Y6M9,P13073,Q8N183,Q7L592,Q8N8Q8,Q86Y39,Q9NPL8,P03886,P00403,P56556,O14949 | Processes and pathways | Reactome Pathways | msigdb_reactome | 512,646,17,275,154,28,659,679,287,436,201,468,595,341,350,624,247,380,125,127 | 1893,659,127,287,17,1575,2562,1760,1863,1539,825,275,1210,2381,646,1360,1256,380,247,1050,1517,1367,201,2976,808,880,3206,711,755,512,3305,2196,1491,3051,1932,1470,3285,1677,125,1909,1378,154,2458,595,350,468,341,1476,679,944,1949,1728,624,1173,1891,3336,28,436 | -0.233383556658795,0.66884230281273,1.9625683440442812,1.3240769098404388,3.5198547952428183,-0.057841396040278596,-0.610941794333371,-0.16284975656285822,-0.21570997527597668,-0.04043100103272851,0.47039145099938634,1.355195299175073,0.16651906993514767,-0.5017886709334725,0.6852366133893191,0.06349529754497407,0.13227671324131024,1.088262751441023,1.417209198502823,0.26866237124034603,-0.02304631237539939,0.06349529754497407,1.6015036764204846,-0.9073124362309171,0.4870521174821247,0.4202725426034364,-1.211869368833104,0.5865431038553878,0.5368984476537072,0.8641627985338416,-1.5451951225647298,-0.39367279234365044,-0.0056872218402178,-0.9637739539367629,-0.25108408655359427,0.011646378050987276,-1.4460659147478525,-0.1102279128477972,1.9922224857685245,-0.233383556658795,0.06349529754497407,1.8283105702783014,-0.5380563923449663,0.7505981648073553,1.151571535639279,0.9285979925872347,1.1673498693322624,0.011646378050987276,0.6524262597868276,0.3699463810201887,-0.25108408655359427,-0.12774223079298147,0.7179603649304444,0.20066360371072753,-0.21570997527597668,-1.910089858268988,3.210810725503896,0.9927055249531092 | 3,381 |
Ventricular hypertrophy | 11 | 42 | 2.283105 | 0.022424 | P02545,P36543,Q9H9S5,O43772,O75880,O00170,O75431,P03886,O75208,P00403,O75844 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 4,324,75,296,275,279,88,247,246,380,159 | 279,3140,296,246,88,159,275,1362,380,1124,4,247,2041,1051,2497,1309,1735,755,1129,929,2196,1031,809,324,2785,1545,2709,882,2939,722,1472,1748,852,478,1687,389,3089,2988,653,3284,1426,75 | 1.3396454442052559,-1.0966598820951519,1.2772585855164569,1.417209198502823,2.314221925162671,1.8133097539294933,1.355195299175073,0.06349529754497407,1.088262751441023,0.21769943580617096,4.32249087085326,1.417209198502823,-0.3221580605870234,0.26866237124034603,-0.5744404092580189,0.09793572799284321,-0.14528280773655003,0.5368984476537072,0.21769943580617096,0.3699463810201887,-0.39367279234365044,0.285602152936856,0.4870521174821247,1.1988483827647884,-0.7581430518565561,-0.04043100103272851,-0.7027159312432755,0.4202725426034364,-0.8698314423424568,0.5700171494918655,0.011646378050987276,-0.14528280773655003,0.45370802586662823,0.9125200992112816,-0.1102279128477972,1.0723863455217324,-1.0015768198922248,-0.9073124362309171,0.6852366133893191,-1.4263514230376444,0.04623753210788857,2.4581284970631354 | 3,381 |
oxidase | 8 | 17 | 2.282284 | 0.022473 | Q9NVS9,P13073,P14406,Q15800,O75880,Q6ZRP7,P36551,O14548 | Functions | Panther Protein class | panther_protein_class | 35,201,9,621,275,410,381,659 | 659,1575,2039,1028,275,1367,201,9,880,711,381,1768,621,3032,410,1531,35 | 0.66884230281273,-0.057841396040278596,-0.3221580605870234,0.285602152936856,1.355195299175073,0.06349529754497407,1.6015036764204846,3.978155059571171,0.4202725426034364,0.5865431038553878,1.088262751441023,-0.16284975656285822,0.7179603649304444,-0.9449212358676787,1.0405739895843595,-0.02304631237539939,2.991897301369138 | 3,381 |
Receptor mediated endocytosis | 16 | 56 | 2.281945 | 0.022493 | Q13614,P01130,O75955,P61978,P05067,P50897,Q07954,P10909,P46934,Q13596,Q96D71,P98164,P62993,P30533,Q5VW38,P50570 | Processes and pathways | GO Biological process | msigdb_gobp | 161,537,292,214,132,100,489,167,45,527,49,428,438,463,57,514 | 2376,1830,2352,2828,292,2625,3047,537,991,132,1900,2042,992,167,1052,768,953,1369,1903,463,2159,1469,45,514,100,1520,214,3267,438,2165,2232,428,2127,2455,634,489,1939,527,161,554,2613,1219,1940,2510,761,57,1625,797,2892,49,2145,3092,3224,1665,1793,1829 | -0.5017886709334725,-0.19806322542449376,-0.48369809024111093,-0.7952479551162744,1.292883545349269,-0.6475616366576715,-0.9637739539367629,0.8318208221873443,0.3194104967216977,1.9328488984240189,-0.233383556658795,-0.3221580605870234,0.3194104967216977,1.7832575080155384,0.26866237124034603,0.5203055281119934,0.3531245121268438,0.06349529754497407,-0.233383556658795,0.9285979925872347,-0.37575235994719464,0.011646378050987276,2.853367256267709,0.8641627985338416,2.2271528467595973,-0.02304631237539939,1.5556721976735917,-1.3870322116472107,0.9767091001145846,-0.37575235994719464,-0.41162126510560293,0.9927055249531092,-0.3578598430231122,-0.5380563923449663,0.7016092735780922,0.8964216526892619,-0.25108408655359427,0.8480022389189762,1.8133097539294933,0.8156184711857695,-0.6292368396202702,0.16651906993514767,-0.25108408655359427,-0.5744404092580189,0.5368984476537072,2.685334028564175,-0.07527760638334166,0.5036901138602248,-0.8324770201433779,2.783595018898293,-0.3578598430231122,-1.0015768198922248,-1.2505475372844703,-0.09273974181183568,-0.16284975656285822,-0.18044319095933925 | 3,381 |
Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen | 8 | 35 | 2.277034 | 0.022784 | O15460,P30519,P09601,Q16850,Q6UW02,Q32P28,P61457,P13674 | Functions | GO Molecular function | msigdb_gomf | 104,74,13,241,86,155,348,31 | 2878,1304,104,2039,1895,3046,1028,1074,1126,13,31,662,1866,74,348,2021,1809,830,621,241,155,3030,1322,503,86,2686,2581,870,1531,395,3091,1481,1484,2471,2412 | -0.8324770201433779,0.09793572799284321,2.1834104512228016,-0.3221580605870234,-0.233383556658795,-0.9637739539367629,0.285602152936856,0.2516987221968761,0.21769943580617096,3.783448138156203,3.115443134937958,0.66884230281273,-0.21570997527597668,2.4581284970631354,1.151571535639279,-0.3043485498283727,-0.18044319095933925,0.47039145099938634,0.7179603649304444,1.4481057172341323,1.8283105702783014,-0.9449212358676787,0.09793572799284321,0.8803025777169821,2.34312313256838,-0.6843010420962635,-0.610941794333371,0.4370017529662837,-0.02304631237539939,1.0723863455217324,-1.0015768198922248,0.011646378050987276,0.011646378050987276,-0.5380563923449663,-0.5017886709334725 | 3,381 |
Severe muscular hypotonia | 12 | 33 | 2.273564 | 0.022992 | Q9GZY8,Q9NWM8,P02545,P40855,Q05639,Q9Y5Y5,Q9H9S5,O75381,Q00577,Q01105,Q8TD16,P06753 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 396,66,4,256,387,301,75,486,526,58,188,218 | 709,1863,486,898,927,4,218,3084,256,524,2286,1442,2083,2051,526,2127,58,387,901,1808,2763,2811,3158,2175,188,3107,3074,3136,396,75,1354,66,301 | 0.5865431038553878,-0.21570997527597668,0.8964216526892619,0.40352030450058385,0.3699463810201887,4.32249087085326,1.5403594847627644,-1.0015768198922248,1.3862392263267762,0.8480022389189762,-0.44760283593211736,0.028954594033709185,-0.3399951175936339,-0.3221580605870234,0.8480022389189762,-0.3578598430231122,2.6712408389899127,1.0723863455217324,0.40352030450058385,-0.18044319095933925,-0.7396367924488996,-0.7766800572431602,-1.1157765393410726,-0.37575235994719464,1.707829097433171,-1.0205272889889005,-0.9826590952942919,-1.0775767957654838,1.0723863455217324,2.4581284970631354,0.08072799489487778,2.60056263958199,1.2772585855164569 | 3,381 |
Mitophagy | 6 | 11 | 2.267941 | 0.023333 | Q8N4H5,Q9NS69,P21796,Q13501,Q15388,Q8IWA4 | Processes and pathways | Reactome Pathways | msigdb_reactome | 33,5,199,429,465,450 | 1336,568,2227,199,2083,429,465,450,33,2239,5 | 0.08072799489487778,0.7831506553954769,-0.41162126510560293,1.6319696996489776,-0.3399951175936339,0.9927055249531092,0.9285979925872347,0.9606924188585974,3.046937180331755,-0.41162126510560293,4.32249087085326 | 3,381 |
Rimmed vacuoles | 10 | 16 | 2.263284 | 0.023618 | P31483,P02545,P22626,P50402,P35609,Q13501,Q86U42,P43243,Q8WXH0,O14979 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 416,4,298,303,809,429,558,616,731,187 | 187,4,849,298,416,809,616,303,1313,429,1748,558,731,1352,2662,1983 | 1.707829097433171,4.32249087085326,0.45370802586662823,1.2772585855164569,1.0246378972585815,0.4870521174821247,0.7179603649304444,1.2616146868698537,0.09793572799284321,0.9927055249531092,-0.14528280773655003,0.7993951082889633,0.5700171494918655,0.08072799489487778,-0.6659163242058336,-0.2688116827850815 | 3,381 |
Primary active transmembrane transporter activity | 21 | 57 | 2.260284 | 0.023804 | O95298,O43676,Q16718,Q9UDW1,O14548,O43674,Q9Y6M9,Q9HD20,P05026,P13073,P36543,P20674,P61421,Q15388,Q9Y5K8,P08183,P06576,P03886,P51798,P00403,P56556 | Functions | GO Molecular function | msigdb_gomf | 646,17,154,28,659,287,436,47,688,201,324,711,591,465,614,219,371,247,497,380,125 | 1893,659,3234,287,17,1235,2562,1760,1863,1539,825,1210,2381,646,1360,1256,380,247,911,688,371,219,1050,1367,201,994,3206,740,711,1865,3068,1837,3305,1491,2158,324,1673,1470,3285,497,1677,125,591,1110,1037,2361,465,154,2458,47,1433,2769,3336,28,1330,614,436 | -0.233383556658795,0.66884230281273,-1.3088274981671097,1.3240769098404388,3.5198547952428183,0.14941016954971006,-0.610941794333371,-0.16284975656285822,-0.21570997527597668,-0.04043100103272851,0.47039145099938634,0.16651906993514767,-0.5017886709334725,0.6852366133893191,0.06349529754497407,0.13227671324131024,1.088262751441023,1.417209198502823,0.3867449477923637,0.6359884017355526,1.1041194035027075,1.5403594847627644,0.26866237124034603,0.06349529754497407,1.6015036764204846,0.3194104967216977,-1.211869368833104,0.5534689593446168,0.5865431038553878,-0.21570997527597668,-0.9826590952942919,-0.19806322542449376,-1.5451951225647298,-0.0056872218402178,-0.37575235994719464,1.1988483827647884,-0.1102279128477972,0.011646378050987276,-1.4460659147478525,0.8803025777169821,-0.1102279128477972,1.9922224857685245,0.7505981648073553,0.2347111094017979,0.285602152936856,-0.48369809024111093,0.9285979925872347,1.8283105702783014,-0.5380563923449663,2.7975768714129026,0.04623753210788857,-0.7396367924488996,-1.910089858268988,3.210810725503896,0.09793572799284321,0.7342899684920763,0.9927055249531092 | 3,381 |
Abnormal visual electrophysiology | 14 | 48 | 2.258537 | 0.023912 | Q9GZY8,O60220,P50897,Q04837,O43172,P51798,P07602,Q15555,P00846,Q9NZJ7,Q96S66,Q8IY17,O14773,Q15067 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 396,121,100,386,383,497,81,374,54,377,549,411,318,449 | 318,383,2442,536,1795,3017,121,767,1096,2318,2014,3123,54,81,1309,2729,1493,1545,2568,100,1374,497,2231,386,852,1551,449,374,834,3149,2293,1720,411,2336,2868,855,1879,1423,549,1659,396,1566,1271,2246,1432,2699,377,2928 | 1.2145686983078836,1.0723863455217324,-0.5380563923449663,0.8318208221873443,-0.18044319095933925,-0.9449212358676787,2.0070251955300082,0.5203055281119934,0.2347111094017979,-0.4656361884453895,-0.3043485498283727,-1.0585271123335283,2.727529421964283,2.4007449963234015,0.09793572799284321,-0.7211611336557268,-0.0056872218402178,-0.04043100103272851,-0.610941794333371,2.2271528467595973,0.06349529754497407,0.8803025777169821,-0.41162126510560293,1.0723863455217324,0.45370802586662823,-0.04043100103272851,0.9606924188585974,1.1041194035027075,0.47039145099938634,-1.0966598820951519,-0.44760283593211736,-0.12774223079298147,1.0405739895843595,-0.4656361884453895,-0.8138468931391319,0.45370802586662823,-0.21570997527597668,0.04623753210788857,0.8318208221873443,-0.09273974181183568,1.0723863455217324,-0.04043100103272851,0.13227671324131024,-0.41162126510560293,0.04623753210788857,-0.6843010420962635,1.1041194035027075,-0.8511384861420023 | 3,381 |
Abnormal atrioventricular valve morphology | 15 | 36 | 2.257199 | 0.023996 | P54198,P02545,Q6DKJ4,O60826,P55795,P36543,Q15233,Q06787,P21964,Q15056,O00192,P53701,O75431,P06753,O75844 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 539,4,421,600,233,324,478,634,12,542,370,316,88,218,159 | 1860,370,2220,600,88,159,4,687,218,3264,12,1129,1467,1766,324,2709,2163,316,2677,539,233,2545,2021,3101,634,1849,542,478,421,2814,2742,1880,2767,1173,2490,842 | -0.21570997527597668,1.1041194035027075,-0.41162126510560293,0.7342899684920763,2.314221925162671,1.8133097539294933,4.32249087085326,0.6359884017355526,1.5403594847627644,-1.3870322116472107,3.8486291662636134,0.21769943580617096,0.011646378050987276,-0.16284975656285822,1.1988483827647884,-0.7027159312432755,-0.37575235994719464,1.23026980961867,-0.6843010420962635,0.8318208221873443,1.4943138534902085,-0.5926763630965615,-0.3043485498283727,-1.0205272889889005,0.7016092735780922,-0.19806322542449376,0.8318208221873443,0.9125200992112816,1.0086817664528895,-0.7766800572431602,-0.7211611336557268,-0.21570997527597668,-0.7396367924488996,0.20066360371072753,-0.5562337972034157,0.47039145099938634 | 3,381 |
Gpcr ligand binding | 6 | 10 | 2.256183 | 0.024059 | P04083,P05067,Q9BYT8,P42892,P07602,Q9NZJ7 | Processes and pathways | Reactome Pathways | msigdb_reactome | 415,132,368,140,81,377 | 415,132,81,140,1284,368,587,377,1664,2594 | 1.0246378972585815,1.9328488984240189,2.4007449963234015,1.9030637360185523,0.11511859996624757,1.1199563718210412,0.7668850339236268,1.1041194035027075,-0.09273974181183568,-0.610941794333371 | 3,381 |
Scotoma | 7 | 14 | 2.253313 | 0.024239 | P04439,Q9Y287,P00846,P03886,O60220,Q9H061,Q8WWV3 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 192,245,54,247,121,30,351 | 924,2442,121,767,1760,54,247,192,2882,351,3175,30,375,245 | 0.3699463810201887,-0.5380563923449663,2.0070251955300082,0.5203055281119934,-0.16284975656285822,2.727529421964283,1.417209198502823,1.6623656284021715,-0.8324770201433779,1.151571535639279,-1.1349269369210717,3.156391655179004,1.1041194035027075,1.4326666084227007 | 3,381 |
Mitochondrial calcium ion transport | 12 | 16 | 2.249927 | 0.024454 | Q9UJZ1,O95202,Q99623,Q9Y277,P21796,Q10713,Q9BPX6,Q96TA2,P45880,Q9NWR8,Q9Y4W6,Q8IYU8 | Processes and pathways | Reactome Pathways | msigdb_reactome | 683,131,1044,1012,199,1001,471,798,184,484,382,451 | 1181,131,199,1468,184,1001,451,1085,1596,798,1044,471,484,683,1012,382 | 0.18360351475980163,1.9328488984240189,1.6319696996489776,0.011646378050987276,1.7229490341498392,0.3194104967216977,0.9606924188585974,0.2516987221968761,-0.057841396040278596,0.5036901138602248,0.285602152936856,0.9285979925872347,0.9125200992112816,0.6524262597868276,0.3194104967216977,1.088262751441023 | 3,381 |
Action tremor | 20 | 55 | 2.248918 | 0.024518 | Q8TAB3,P31749,Q8IY17,Q01082,O43681,Q14108,P20700,P00846,O14773,Q5JRX3,Q5T8D3,P35637,P07602,Q15233,Q9Y287,Q9H6K4,P03886,Q9NZJ7,Q9UBB4,Q9Y4W6 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 392,269,411,540,536,554,297,54,318,197,580,77,81,478,245,375,247,377,641,382 | 3217,318,2530,823,536,1235,1760,1832,2597,54,247,1577,81,2727,1338,1581,769,297,1128,2630,269,3049,77,2159,758,2121,2453,1935,540,634,554,478,3157,197,580,2131,2969,411,1386,1816,392,1351,3272,3308,693,375,1354,1887,875,2468,377,641,1456,245,382 | -1.2505475372844703,1.2145686983078836,-0.5926763630965615,0.47039145099938634,0.8318208221873443,0.14941016954971006,-0.16284975656285822,-0.19806322542449376,-0.6292368396202702,2.727529421964283,1.417209198502823,-0.057841396040278596,2.4007449963234015,-0.7211611336557268,0.08072799489487778,-0.057841396040278596,0.5203055281119934,1.2772585855164569,0.21769943580617096,-0.6475616366576715,1.3707265386892524,-0.9637739539367629,2.4294663659270506,-0.37575235994719464,0.5368984476537072,-0.3578598430231122,-0.5380563923449663,-0.25108408655359427,0.8318208221873443,0.7016092735780922,0.8156184711857695,0.9125200992112816,-1.1157765393410726,1.647176397021248,0.7668850339236268,-0.3578598430231122,-0.8885560411599439,1.0405739895843595,0.06349529754497407,-0.18044319095933925,1.0723863455217324,0.08072799489487778,-1.3870322116472107,-1.585110386151516,0.6359884017355526,1.1041194035027075,0.08072799489487778,-0.21570997527597668,0.4370017529662837,-0.5380563923449663,1.1041194035027075,0.7016092735780922,0.028954594033709185,1.4326666084227007,1.088262751441023 | 3,381 |
Apical plasma membrane | 18 | 50 | 2.244449 | 0.024804 | P04083,O75955,Q99797,P36543,O43865,P20020,P53985,O00165,P30825,Q13277,P05026,P98164,P61421,Q16625,P36551,P78536,Q9Y6M7,P08183 | Localization | GO Cellular component | msigdb_gocc | 415,292,7,324,485,740,236,738,240,306,688,428,591,501,381,722,252,219 | 738,2849,2315,823,485,292,1961,415,911,688,950,219,1578,2852,1708,3181,768,1902,740,1865,1836,240,2158,1406,324,381,1673,2159,1036,236,1616,1643,591,722,428,1056,1415,306,1684,2168,501,1040,2026,7,1509,2246,1150,3015,3225,252 | 0.5534689593446168,-0.8138468931391319,-0.4656361884453895,0.47039145099938634,0.8964216526892619,1.292883545349269,-0.2688116827850815,1.0246378972585815,0.3867449477923637,0.6359884017355526,0.3531245121268438,1.5403594847627644,-0.057841396040278596,-0.8138468931391319,-0.12774223079298147,-1.154111245668569,0.5203055281119934,-0.233383556658795,0.5534689593446168,-0.21570997527597668,-0.19806322542449376,1.4481057172341323,-0.37575235994719464,0.04623753210788857,1.1988483827647884,1.088262751441023,-0.1102279128477972,-0.37575235994719464,0.285602152936856,1.463526586756026,-0.07527760638334166,-0.09273974181183568,0.7505981648073553,0.5700171494918655,0.9927055249531092,0.26866237124034603,0.04623753210788857,1.2459517836247969,-0.1102279128477972,-0.37575235994719464,0.8803025777169821,0.285602152936856,-0.3043485498283727,4.144909340259825,-0.0056872218402178,-0.41162126510560293,0.21769943580617096,-0.9261007824267626,-1.2505475372844703,1.4017334253090765 | 3,381 |
Slc mediated transmembrane transport | 7 | 23 | 2.242238 | 0.024946 | P53985,Q8NEW0,P30825,Q9UBX3,Q70HW3,Q9Y6M7,Q8TB61 | Processes and pathways | Reactome Pathways | msigdb_reactome | 236,433,240,178,51,252,412 | 2646,1578,1309,1542,1077,240,1018,757,236,1643,1446,981,2945,51,433,412,559,1509,2272,1271,178,3015,252 | -0.6659163242058336,-0.057841396040278596,0.09793572799284321,-0.04043100103272851,0.2516987221968761,1.4481057172341323,0.30251816305270063,0.5368984476537072,1.463526586756026,-0.09273974181183568,0.028954594033709185,0.33627924845100304,-0.8698314423424568,2.755589935882612,0.9927055249531092,1.0405739895843595,0.7993951082889633,-0.0056872218402178,-0.4295979040509883,0.13227671324131024,1.7531374146957515,-0.9261007824267626,1.4017334253090765 | 3,381 |
Midbrain development | 11 | 21 | 2.234464 | 0.025453 | P0DP25,O75489,Q5T9L3,O15027,Q8IXJ6,P62258,Q04917,P12277,Q16352,P00367,O14949 | Processes and pathways | GO Biological process | msigdb_gobp | 294,825,169,671,175,810,633,689,251,569,127 | 127,671,825,569,2535,294,1797,689,914,1543,1185,1845,2605,810,1937,1547,633,251,169,175,2038 | 1.9625683440442812,0.6524262597868276,0.47039145099938634,0.7831506553954769,-0.5926763630965615,1.292883545349269,-0.18044319095933925,0.6359884017355526,0.3867449477923637,-0.04043100103272851,0.18360351475980163,-0.19806322542449376,-0.6292368396202702,0.4870521174821247,-0.25108408655359427,-0.04043100103272851,0.7016092735780922,1.4017334253090765,1.7832575080155384,1.7682059696602237,-0.3043485498283727 | 3,381 |
Regulation of blood pressure | 6 | 18 | 2.224393 | 0.026122 | Q6P179,P42892,P09601,Q9Y5X3,Q9UIQ6,P09493 | Processes and pathways | GO Biological process | msigdb_gobp | 163,140,13,238,111,79 | 3273,911,79,13,3235,740,881,140,2710,2605,2051,1685,163,1953,1393,289,111,238 | -1.4066735867376003,0.3867449477923637,2.4151131078172017,3.783448138156203,-1.3088274981671097,0.5534689593446168,0.4202725426034364,1.9030637360185523,-0.7027159312432755,-0.6292368396202702,-0.3221580605870234,-0.1102279128477972,1.7982920845921333,-0.25108408655359427,0.06349529754497407,1.3084896317780137,2.154171009391761,1.463526586756026 | 3,381 |
Peptide catabolic process | 6 | 11 | 2.22268 | 0.026237 | Q9NZ08,Q6P179,P42892,Q9UIQ6,P55786,O14773 | Processes and pathways | GO Biological process | msigdb_gobp | 289,163,140,111,113,318 | 318,337,2194,140,113,163,888,2748,2795,289,111 | 1.2145686983078836,1.1673498693322624,-0.39367279234365044,1.9030637360185523,2.1248688461959304,1.7982920845921333,0.4202725426034364,-0.7211611336557268,-0.7581430518565561,1.3084896317780137,2.154171009391761 | 3,381 |
Nephrotic syndrome | 7 | 30 | 2.220813 | 0.026364 | O95721,P00813,Q9BW27,O95470,Q03252,Q8NCH0,Q8N1F7 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 254,6,459,520,145,80,548 | 520,254,6,2041,2497,1239,1409,1617,1241,145,3055,1472,886,1414,554,2365,1720,3114,548,80,1447,2267,1424,1691,873,459,1659,1601,1432,2215 | 0.8480022389189762,1.3862392263267762,4.246634283440154,-0.3221580605870234,-0.5744404092580189,0.14941016954971006,0.04623753210788857,-0.07527760638334166,0.14941016954971006,1.8732124396128473,-0.9637739539367629,0.011646378050987276,0.4202725426034364,0.04623753210788857,0.8156184711857695,-0.48369809024111093,-0.12774223079298147,-1.0395106651639698,0.8318208221873443,2.4151131078172017,0.028954594033709185,-0.4295979040509883,0.04623753210788857,-0.1102279128477972,0.4370017529662837,0.944655407668733,-0.09273974181183568,-0.057841396040278596,0.04623753210788857,-0.39367279234365044 | 3,381 |
Regulation of macroautophagy | 18 | 57 | 2.216599 | 0.026651 | Q9Y487,Q8TBX8,Q93050,Q15382,Q9UNH7,P21796,P36543,P09601,P31749,P46934,Q9Y5K8,Q9Y5X3,P04062,P61421,O15269,Q9NQ88,P49815,Q9UMX0 | Processes and pathways | GO Biological process | msigdb_gobp | 64,776,71,774,820,199,324,13,269,45,614,238,687,591,802,800,663,222 | 1706,1513,802,2351,1761,1928,687,2904,1899,1540,2646,3048,1734,13,1309,2782,1865,3068,199,1490,1030,269,324,1673,1439,1615,45,663,591,1846,1413,2763,1551,774,1420,1688,776,940,71,836,2298,2716,1198,2869,1566,2949,800,1149,1330,222,820,1486,1122,1731,64,614,238 | -0.12774223079298147,-0.02304631237539939,0.4870521174821247,-0.48369809024111093,-0.16284975656285822,-0.25108408655359427,0.6359884017355526,-0.8511384861420023,-0.233383556658795,-0.04043100103272851,-0.6659163242058336,-0.9637739539367629,-0.14528280773655003,3.783448138156203,0.09793572799284321,-0.7581430518565561,-0.21570997527597668,-0.9826590952942919,1.6319696996489776,-0.0056872218402178,0.285602152936856,1.3707265386892524,1.1988483827647884,-0.1102279128477972,0.028954594033709185,-0.07527760638334166,2.853367256267709,0.66884230281273,0.7505981648073553,-0.19806322542449376,0.04623753210788857,-0.7396367924488996,-0.04043100103272851,0.5203055281119934,0.04623753210788857,-0.1102279128477972,0.5203055281119934,0.3699463810201887,2.5010113820047586,0.47039145099938634,-0.44760283593211736,-0.7027159312432755,0.18360351475980163,-0.8138468931391319,-0.04043100103272851,-0.8698314423424568,0.5036901138602248,0.21769943580617096,0.09793572799284321,1.5403594847627644,0.4870521174821247,0.011646378050987276,0.2347111094017979,-0.12774223079298147,2.628876532164271,0.7342899684920763,1.463526586756026 | 3,381 |
EF-Hand 1, calcium-binding site [IPR018247] | 14 | 40 | 2.215539 | 0.026723 | Q9NWM8,O95202,P0DP25,P80303,P12814,Q9UBV8,Q9Y680,O43707,Q96D71,Q9BPX6,O95302,O43852,P41208,Q14257 | Sequence | InterPro Binding site | interpro_binding_site | 66,131,294,38,488,300,43,332,49,471,208,85,116,55 | 332,85,2378,898,131,208,1899,3048,294,488,3347,1368,3275,2018,1077,3346,116,1469,975,38,2983,3358,528,55,1848,650,1687,984,1780,1196,49,471,597,746,1300,66,1011,300,1155,43 | 1.1831087956745996,2.34312313256838,-0.5017886709334725,0.40352030450058385,1.9328488984240189,1.570967094546599,-0.233383556658795,-0.9637739539367629,1.292883545349269,0.8964216526892619,-2.2032175307634096,0.06349529754497407,-1.4066735867376003,-0.3043485498283727,0.2516987221968761,-2.1608130336419897,2.080797152869033,0.011646378050987276,0.33627924845100304,2.9504787368329666,-0.9073124362309171,-2.6376670739602184,0.8480022389189762,2.727529421964283,-0.19806322542449376,0.6852366133893191,-0.1102279128477972,0.33627924845100304,-0.16284975656285822,0.18360351475980163,2.783595018898293,0.9285979925872347,0.7505981648073553,0.5534689593446168,0.11511859996624757,2.60056263958199,0.3194104967216977,1.2772585855164569,0.21769943580617096,2.881180768821156 | 3,381 |
Peripheral axonal degeneration | 19 | 68 | 2.215349 | 0.026736 | Q9BQT8,P02545,Q9H0B6,Q8IY17,P22626,P00846,Q15067,P07196,Q9NVI7,P07602,Q9BPX6,Q96BR5,Q6DKK2,P03886,Q9NZJ7,P00403,Q9Y4W6,P50570,Q8IV08 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 262,4,158,411,298,54,449,69,461,81,471,231,105,247,377,380,382,514,258 | 802,2351,2596,767,511,2251,848,927,380,54,4,247,2672,69,3048,81,2074,849,1309,3096,2226,298,2978,2567,3049,1079,2159,1519,2884,514,2200,2387,1935,1313,1617,1082,2021,1808,1871,2811,2576,449,2812,1588,3158,105,1555,1688,2790,258,411,1268,890,231,2139,1351,1426,471,262,2369,158,2699,461,2147,377,2558,382,2414 | 0.4870521174821247,-0.48369809024111093,-0.6292368396202702,0.5203055281119934,0.8641627985338416,-0.4295979040509883,0.45370802586662823,0.3699463810201887,1.088262751441023,2.727529421964283,4.32249087085326,1.417209198502823,-0.6843010420962635,2.5152764326345016,-0.9637739539367629,2.4007449963234015,-0.3399951175936339,0.45370802586662823,0.09793572799284321,-1.0205272889889005,-0.41162126510560293,1.2772585855164569,-0.9073124362309171,-0.610941794333371,-0.9637739539367629,0.2516987221968761,-0.37575235994719464,-0.02304631237539939,-0.8324770201433779,0.8641627985338416,-0.39367279234365044,-0.5017886709334725,-0.25108408655359427,0.09793572799284321,-0.07527760638334166,0.2516987221968761,-0.3043485498283727,-0.18044319095933925,-0.21570997527597668,-0.7766800572431602,-0.610941794333371,0.9606924188585974,-0.7766800572431602,-0.057841396040278596,-1.1157765393410726,2.1834104512228016,-0.04043100103272851,-0.1102279128477972,-0.7581430518565561,1.3862392263267762,1.0405739895843595,0.13227671324131024,0.4202725426034364,1.509680372631674,-0.3578598430231122,0.08072799489487778,0.04623753210788857,0.9285979925872347,1.3862392263267762,-0.48369809024111093,1.8283105702783014,-0.6843010420962635,0.944655407668733,-0.3578598430231122,1.1041194035027075,-0.5926763630965615,1.088262751441023,-0.5017886709334725 | 3,381 |
oxidoreductase | 13 | 48 | 2.215116 | 0.026752 | O43674,O15254,Q6DKJ4,O95825,Q9Y6M9,O43676,O43169,P00403,Q8N4Q0,Q16718,P56556,Q86Y39,O14949 | Functions | Panther Protein class | panther_protein_class | 287,129,421,255,436,17,83,380,90,154,125,350,127 | 1893,127,129,83,1208,287,17,1760,1863,1210,2381,646,255,927,1256,380,3273,1257,2976,662,2882,787,3182,3051,632,3285,1677,125,1473,1683,449,1378,1941,154,2458,3148,421,350,1626,90,1148,3256,2657,2408,1173,2247,2527,436 | -0.233383556658795,1.9625683440442812,1.9477168099260758,2.3719640368293593,0.16651906993514767,1.3240769098404388,3.5198547952428183,-0.16284975656285822,-0.21570997527597668,0.16651906993514767,-0.5017886709334725,0.6852366133893191,1.3862392263267762,0.3699463810201887,0.13227671324131024,1.088262751441023,-1.4066735867376003,0.13227671324131024,-0.9073124362309171,0.66884230281273,-0.8324770201433779,0.5036901138602248,-1.154111245668569,-0.9637739539367629,0.7016092735780922,-1.4460659147478525,-0.1102279128477972,1.9922224857685245,0.011646378050987276,-0.1102279128477972,0.9606924188585974,0.06349529754497407,-0.25108408655359427,1.8283105702783014,-0.5380563923449663,-1.0966598820951519,1.0086817664528895,1.151571535639279,-0.07527760638334166,2.314221925162671,0.21769943580617096,-1.347858076733306,-0.6659163242058336,-0.5017886709334725,0.20066360371072753,-0.41162126510560293,-0.5744404092580189,0.9927055249531092 | 3,381 |
Abnormal mitochondria in muscle tissue | 8 | 23 | 2.214619 | 0.026786 | Q9Y6M9,Q96CU9,O43676,P56556,P03886,P00403,Q9Y4W6,Q86Y39 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 436,14,17,125,247,380,382,350 | 17,2562,1760,1863,825,1256,380,247,3206,3305,2196,3285,125,350,468,1476,14,1949,624,1173,1891,382,436 | 3.5198547952428183,-0.610941794333371,-0.16284975656285822,-0.21570997527597668,0.47039145099938634,0.13227671324131024,1.088262751441023,1.417209198502823,-1.211869368833104,-1.5451951225647298,-0.39367279234365044,-1.4460659147478525,1.9922224857685245,1.151571535639279,0.9285979925872347,0.011646378050987276,3.665405898737808,-0.25108408655359427,0.7179603649304444,0.20066360371072753,-0.21570997527597668,1.088262751441023,0.9927055249531092 | 3,381 |
Protein localization to endoplasmic reticulum | 12 | 38 | 2.213527 | 0.026861 | P46379,Q9UGP8,O43681,Q13438,Q15629,O43731,Q9NQC3,Q96HY6,P24390,Q5JRA6,P33908,O43765 | Processes and pathways | GO Biological process | msigdb_gobp | 476,226,536,490,72,92,203,205,19,467,59,191 | 671,1305,1180,536,92,191,2222,1278,603,1054,19,59,2448,476,1713,1107,3325,2259,2388,2571,1805,3146,490,1686,1551,72,467,2740,1781,205,1427,1566,2949,203,2275,226,1955,822 | 0.6524262597868276,0.09793572799284321,0.18360351475980163,0.8318208221873443,2.299748594818239,1.6775374510295888,-0.41162126510560293,0.11511859996624757,0.7342899684920763,0.26866237124034603,3.4264829524837057,2.6571335533557483,-0.5380563923449663,0.9125200992112816,-0.12774223079298147,0.2347111094017979,-1.7870173720445042,-0.4295979040509883,-0.5017886709334725,-0.610941794333371,-0.18044319095933925,-1.0966598820951519,0.8964216526892619,-0.1102279128477972,-0.04043100103272851,2.4867317377474243,0.9285979925872347,-0.7211611336557268,-0.16284975656285822,1.5862442345229415,0.04623753210788857,-0.04043100103272851,-0.8698314423424568,1.6015036764204846,-0.4295979040509883,1.5250288963471914,-0.25108408655359427,0.4870521174821247 | 3,381 |
Oxidase | 8 | 22 | 2.209098 | 0.027168 | O15254,Q9NVS9,P14406,O43169,O15260,O75880,Q6ZRP7,P36551 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 129,35,9,83,213,275,410,381 | 659,129,213,83,1575,1028,275,1367,3360,2976,9,880,711,3021,381,2199,449,621,410,814,1728,35 | 0.66884230281273,1.9477168099260758,1.5556721976735917,2.3719640368293593,-0.057841396040278596,0.285602152936856,1.355195299175073,0.06349529754497407,-2.7494110373977514,-0.9073124362309171,3.978155059571171,0.4202725426034364,0.5865431038553878,-0.9449212358676787,1.088262751441023,-0.39367279234365044,0.9606924188585974,0.7179603649304444,1.0405739895843595,0.4870521174821247,-0.12774223079298147,2.991897301369138 | 3,381 |
Progressive gait ataxia | 6 | 12 | 2.20511 | 0.027446 | Q8TAB3,P07602,P00846,Q9NZJ7,O14773,Q05086 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 392,81,54,377,318,417 | 318,823,536,54,81,2075,1935,417,392,1426,2063,377 | 1.2145686983078836,0.47039145099938634,0.8318208221873443,2.727529421964283,2.4007449963234015,-0.3399951175936339,-0.25108408655359427,1.0246378972585815,1.0723863455217324,0.04623753210788857,-0.3221580605870234,1.1041194035027075 | 3,381 |
Steroid binding | 9 | 23 | 2.204211 | 0.027509 | P21796,P38435,Q14108,O00264,Q14849,O15173,O95772,P45880,P30536 | Functions | GO Molecular function | msigdb_gomf | 199,674,554,141,619,50,437,184,315 | 141,1513,50,1016,1017,437,687,911,1987,199,2601,1128,315,1840,674,184,1584,554,619,2061,2104,1951,3204 | 1.8881463808123733,-0.02304631237539939,2.769599386688778,0.30251816305270063,0.30251816305270063,0.9767091001145846,0.6359884017355526,0.3867449477923637,-0.2865664640305207,1.6319696996489776,-0.6292368396202702,0.21769943580617096,1.23026980961867,-0.19806322542449376,0.6524262597868276,1.7229490341498392,-0.057841396040278596,0.8156184711857695,0.7179603649304444,-0.3221580605870234,-0.3399951175936339,-0.25108408655359427,-1.1925822871771383 | 3,381 |
Regulation of pten stability and activity | 13 | 43 | 2.204038 | 0.027522 | P20618,P28074,Q9UL46,P31751,P25787,P28070,P46934,P31749,P28072,P49721,O00231,Q99436,P61289 | Processes and pathways | Reactome Pathways | msigdb_reactome | 130,513,166,136,384,232,45,269,362,399,179,610,320 | 179,3139,910,2880,628,2669,995,2227,130,2728,384,2502,2566,1280,232,362,513,269,136,3050,1674,45,1494,1744,399,1641,1844,1770,320,1215,1714,2330,2083,1134,1548,760,1873,1422,610,2241,166,1456,1826 | 1.7380517879985764,-1.0966598820951519,0.3867449477923637,-0.8324770201433779,0.7016092735780922,-0.6843010420962635,0.3194104967216977,-0.41162126510560293,1.9477168099260758,-0.7211611336557268,1.0723863455217324,-0.5744404092580189,-0.610941794333371,0.11511859996624757,1.4943138534902085,1.1199563718210412,0.8641627985338416,1.3707265386892524,1.9179645577932507,-0.9637739539367629,-0.1102279128477972,2.853367256267709,-0.0056872218402178,-0.14528280773655003,1.0564901152174682,-0.09273974181183568,-0.19806322542449376,-0.16284975656285822,1.2145686983078836,0.16651906993514767,-0.12774223079298147,-0.4656361884453895,-0.3399951175936339,0.21769943580617096,-0.04043100103272851,0.5368984476537072,-0.21570997527597668,0.04623753210788857,0.7342899684920763,-0.41162126510560293,1.7982920845921333,0.028954594033709185,-0.18044319095933925 | 3,381 |
Diffuse mesangial sclerosis | 6 | 21 | 2.201796 | 0.02768 | Q8NFH4,P00813,Q9BW27,O95470,O43707,Q8N1F7 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 327,6,459,520,332,548 | 332,520,6,2497,1409,1241,886,1414,690,1588,2365,548,327,1447,2267,1691,459,1601,2215,1329,1793 | 1.1831087956745996,0.8480022389189762,4.246634283440154,-0.5744404092580189,0.04623753210788857,0.14941016954971006,0.4202725426034364,0.04623753210788857,0.6359884017355526,-0.057841396040278596,-0.48369809024111093,0.8318208221873443,1.1988483827647884,0.028954594033709185,-0.4295979040509883,-0.1102279128477972,0.944655407668733,-0.057841396040278596,-0.39367279234365044,0.09793572799284321,-0.16284975656285822 | 3,381 |
Abnormality of the shoulder girdle musculature | 10 | 36 | 2.199107 | 0.02787 | Q9Y487,P02545,P07196,Q9H9S5,P50402,P07602,Q9NZJ7,O14979,Q8TD16,P06753 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 64,4,69,75,303,81,377,187,188,218 | 3137,924,187,767,2378,3209,4,218,69,81,2497,1309,3264,616,882,303,1313,3101,2942,429,1748,2263,188,731,1426,1352,1353,3240,75,377,2558,2662,64,1983,1091,1571 | -1.0966598820951519,0.3699463810201887,1.707829097433171,0.5203055281119934,-0.5017886709334725,-1.2311910594807025,4.32249087085326,1.5403594847627644,2.5152764326345016,2.4007449963234015,-0.5744404092580189,0.09793572799284321,-1.3870322116472107,0.7179603649304444,0.4202725426034364,1.2616146868698537,0.09793572799284321,-1.0205272889889005,-0.8698314423424568,0.9927055249531092,-0.14528280773655003,-0.4295979040509883,1.707829097433171,0.5700171494918655,0.04623753210788857,0.08072799489487778,0.08072799489487778,-1.3088274981671097,2.4581284970631354,1.1041194035027075,-0.5926763630965615,-0.6659163242058336,2.628876532164271,-0.2688116827850815,0.2516987221968761,-0.04043100103272851 | 3,381 |
Abnormality of the musculature of the lower limbs | 6 | 27 | 2.194495 | 0.0282 | P02545,P07196,Q9H9S5,P50402,P00846,O14979 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 4,69,75,303,54,187 | 187,2596,54,4,69,616,303,514,2286,1313,1808,1748,2811,3169,1445,1555,2790,390,731,2139,1351,1352,75,875,2699,2662,1091 | 1.707829097433171,-0.6292368396202702,2.727529421964283,4.32249087085326,2.5152764326345016,0.7179603649304444,1.2616146868698537,0.8641627985338416,-0.44760283593211736,0.09793572799284321,-0.18044319095933925,-0.14528280773655003,-0.7766800572431602,-1.1349269369210717,0.028954594033709185,-0.04043100103272851,-0.7581430518565561,1.0723863455217324,0.5700171494918655,-0.3578598430231122,0.08072799489487778,0.08072799489487778,2.4581284970631354,0.4370017529662837,-0.6843010420962635,-0.6659163242058336,0.2516987221968761 | 3,381 |
Aurka activation by tpx2 | 13 | 34 | 2.190317 | 0.028501 | P06493,O95684,Q66GS9,O43805,Q9H6D7,Q15154,Q13561,O75935,O75330,P41208,Q14203,Q9BV73,O94927 | Processes and pathways | Reactome Pathways | msigdb_reactome | 474,293,339,41,108,620,574,52,397,116,409,283,151 | 41,397,52,151,293,474,1901,1466,2782,1838,116,3168,2569,1678,1316,810,1937,1318,902,574,2838,409,2811,620,1417,339,3271,1624,1559,668,283,108,2186,2995 | 2.9227997881780685,1.0564901152174682,2.7415666273964714,1.8283105702783014,1.292883545349269,0.9125200992112816,-0.233383556658795,0.011646378050987276,-0.7581430518565561,-0.19806322542449376,2.080797152869033,-1.1349269369210717,-0.610941794333371,-0.1102279128477972,0.09793572799284321,0.4870521174821247,-0.25108408655359427,0.09793572799284321,0.40352030450058385,0.7831506553954769,-0.7952479551162744,1.0405739895843595,-0.7766800572431602,0.7179603649304444,0.04623753210788857,1.1673498693322624,-1.3870322116472107,-0.07527760638334166,-0.04043100103272851,0.66884230281273,1.3396454442052559,2.1687985464903594,-0.37575235994719464,-0.9073124362309171 | 3,381 |
Selective autophagy | 12 | 29 | 2.189552 | 0.028557 | O43464,P53365,P21796,Q5T8D3,Q9Y6I9,Q96HY6,Q13501,O15269,A6NDU8,Q9NQ88,P49815,Q9UMX0 | Processes and pathways | GO Biological process | msigdb_gobp | 162,464,199,580,109,205,429,802,695,800,663,222 | 695,802,2351,162,1337,1540,2646,1309,199,1490,1030,1615,663,1373,2200,464,429,832,580,1688,2094,205,1044,2991,800,222,1069,1759,109 | 0.6195286455637697,0.4870521174821247,-0.48369809024111093,1.7982920845921333,0.08072799489487778,-0.04043100103272851,-0.6659163242058336,0.09793572799284321,1.6319696996489776,-0.0056872218402178,0.285602152936856,-0.07527760638334166,0.66884230281273,0.06349529754497407,-0.39367279234365044,0.9285979925872347,0.9927055249531092,0.47039145099938634,0.7668850339236268,-0.1102279128477972,-0.3399951175936339,1.5862442345229415,0.285602152936856,-0.9073124362309171,0.5036901138602248,1.5403594847627644,0.26866237124034603,-0.14528280773655003,2.1687985464903594 | 3,381 |
Distal amyotrophy | 18 | 63 | 2.176713 | 0.029502 | P31483,Q9BQT8,Q13614,P02545,P07196,Q9NVI7,Q96BR5,Q7Z406,P35637,Q9BUK6,Q13501,Q9Y4W6,Q9H0B6,Q14203,Q8IY17,Q8TD16,P06753,P50570 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 416,262,161,4,69,461,231,456,77,472,429,382,158,409,411,188,218,514 | 802,2351,511,2251,1895,4,2672,218,69,2226,755,2196,416,1031,809,77,1079,2909,616,1519,2121,514,2200,2286,2387,1313,1808,429,1344,161,2546,409,3169,1474,2812,2458,1588,3158,1688,3173,456,411,691,1386,1268,188,890,231,1351,1535,2030,3308,262,472,158,875,461,2898,1456,2662,2594,382,2414 | 0.4870521174821247,-0.48369809024111093,0.8641627985338416,-0.4295979040509883,-0.233383556658795,4.32249087085326,-0.6843010420962635,1.5403594847627644,2.5152764326345016,-0.41162126510560293,0.5368984476537072,-0.39367279234365044,1.0246378972585815,0.285602152936856,0.4870521174821247,2.4294663659270506,0.2516987221968761,-0.8511384861420023,0.7179603649304444,-0.02304631237539939,-0.3578598430231122,0.8641627985338416,-0.39367279234365044,-0.44760283593211736,-0.5017886709334725,0.09793572799284321,-0.18044319095933925,0.9927055249531092,0.08072799489487778,1.8133097539294933,-0.5926763630965615,1.0405739895843595,-1.1349269369210717,0.011646378050987276,-0.7766800572431602,-0.5380563923449663,-0.057841396040278596,-1.1157765393410726,-0.1102279128477972,-1.1349269369210717,0.944655407668733,1.0405739895843595,0.6359884017355526,0.06349529754497407,0.13227671324131024,1.707829097433171,0.4202725426034364,1.509680372631674,0.08072799489487778,-0.02304631237539939,-0.3043485498283727,-1.585110386151516,1.3862392263267762,0.9285979925872347,1.8283105702783014,0.4370017529662837,0.944655407668733,-0.8324770201433779,0.028954594033709185,-0.6659163242058336,-0.610941794333371,1.088262751441023,-0.5017886709334725 | 3,381 |
Abnormality of retinal pigmentation | 24 | 76 | 2.174772 | 0.029647 | P02545,P40855,O43172,P31749,Q96JJ3,Q96CU9,P50542,Q8IY17,Q9UG56,Q9Y5Y5,P25054,P00846,P53701,Q15067,Q9H9S5,P51648,Q8N183,Q9BUK6,Q6P4Q7,Q7Z4L5,O75381,Q15555,P03886,P00403 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 4,256,383,269,146,14,524,411,290,301,44,54,316,449,75,333,468,472,354,123,486,374,247,380 | 1893,2530,383,2442,1795,2596,2562,1760,3209,486,825,2318,2014,848,3123,1360,380,54,4,247,1579,3198,1338,3206,1581,755,44,3305,3252,2196,269,1185,2729,256,1545,758,3285,2568,524,333,2163,1965,316,2939,1442,2261,1551,449,374,2458,1020,3149,354,123,411,468,762,855,1879,1424,14,146,549,944,472,1659,1566,75,2246,1432,1173,3336,290,1091,301,2414 | -0.233383556658795,-0.5926763630965615,1.0723863455217324,-0.5380563923449663,-0.18044319095933925,-0.6292368396202702,-0.610941794333371,-0.16284975656285822,-1.2311910594807025,0.8964216526892619,0.47039145099938634,-0.4656361884453895,-0.3043485498283727,0.45370802586662823,-1.0585271123335283,0.06349529754497407,1.088262751441023,2.727529421964283,4.32249087085326,1.417209198502823,-0.057841396040278596,-1.1925822871771383,0.08072799489487778,-1.211869368833104,-0.057841396040278596,0.5368984476537072,2.853367256267709,-1.5451951225647298,-1.347858076733306,-0.39367279234365044,1.3707265386892524,0.18360351475980163,-0.7211611336557268,1.3862392263267762,-0.04043100103272851,0.5368984476537072,-1.4460659147478525,-0.610941794333371,0.8480022389189762,1.1831087956745996,-0.37575235994719464,-0.2688116827850815,1.23026980961867,-0.8698314423424568,0.028954594033709185,-0.4295979040509883,-0.04043100103272851,0.9606924188585974,1.1041194035027075,-0.5380563923449663,0.30251816305270063,-1.0966598820951519,1.1357737261005323,2.0070251955300082,1.0405739895843595,0.9285979925872347,0.5368984476537072,0.45370802586662823,-0.21570997527597668,0.04623753210788857,3.665405898737808,1.8732124396128473,0.8318208221873443,0.3699463810201887,0.9285979925872347,-0.09273974181183568,-0.04043100103272851,2.4581284970631354,-0.41162126510560293,0.04623753210788857,0.20066360371072753,-1.910089858268988,1.3084896317780137,0.2516987221968761,1.2772585855164569,-0.5017886709334725 | 3,381 |
Fatigable weakness of bulbar muscles | 6 | 16 | 2.17474 | 0.02965 | Q68CQ7,Q15165,P35637,Q14203,P06753,Q92804 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 185,353,77,409,218,63 | 2597,218,2189,849,77,616,1640,1313,2636,429,409,353,185,63,1457,1091 | -0.6292368396202702,1.5403594847627644,-0.39367279234365044,0.45370802586662823,2.4294663659270506,0.7179603649304444,-0.09273974181183568,0.09793572799284321,-0.6475616366576715,0.9927055249531092,1.0405739895843595,1.1357737261005323,1.7229490341498392,2.628876532164271,0.028954594033709185,0.2516987221968761 | 3,381 |
Mitochondrial calcium ion transmembrane transport | 6 | 9 | 2.166809 | 0.030249 | O95202,P21796,Q9BPX6,Q9NWR8,Q9Y4W6,Q8IYU8 | Processes and pathways | GO Biological process | msigdb_gobp | 131,199,471,484,382,451 | 1181,131,199,451,1085,471,484,683,382 | 0.18360351475980163,1.9328488984240189,1.6319696996489776,0.9606924188585974,0.2516987221968761,0.9285979925872347,0.9125200992112816,0.6524262597868276,1.088262751441023 | 3,381 |
Recruitment of mitotic centrosome proteins and complexes | 13 | 36 | 2.166461 | 0.030276 | P06493,O95684,Q66GS9,O43805,Q9H6D7,Q15154,Q13561,Q99996,O75935,P41208,Q14203,Q9BV73,O94927 | Processes and pathways | Reactome Pathways | msigdb_reactome | 474,293,339,41,108,620,574,668,52,116,409,283,151 | 41,52,151,293,474,1901,1466,2782,1765,1838,116,3168,2569,1678,1316,810,1937,1318,902,574,2838,409,2811,620,1417,339,3271,1624,1559,1754,668,699,283,108,2186,2153 | 2.9227997881780685,2.7415666273964714,1.8283105702783014,1.292883545349269,0.9125200992112816,-0.233383556658795,0.011646378050987276,-0.7581430518565561,-0.16284975656285822,-0.19806322542449376,2.080797152869033,-1.1349269369210717,-0.610941794333371,-0.1102279128477972,0.09793572799284321,0.4870521174821247,-0.25108408655359427,0.09793572799284321,0.40352030450058385,0.7831506553954769,-0.7952479551162744,1.0405739895843595,-0.7766800572431602,0.7179603649304444,0.04623753210788857,1.1673498693322624,-1.3870322116472107,-0.07527760638334166,-0.04043100103272851,-0.14528280773655003,0.66884230281273,0.6195286455637697,1.3396454442052559,2.1687985464903594,-0.37575235994719464,-0.3578598430231122 | 3,381 |
Organelle subcompartment | 168 | 399 | 7.719998 | 0 | P24390,Q14108,P49069,Q00765,Q8N0U8,Q15125,P30519,P48651,O43731,Q9BT22,O14828,Q13445,Q6NUK4,P43307,P16615,O00264,O15260,P09601,P04439,P53365,Q9Y282,Q8IV08,Q8TBA6,Q9BQE5,O95772,Q14849,P49257,P51809,Q9BXS4,O43752,Q9Y5Y5,Q15629,Q5BJF2,Q8N511,Q8N2F6,Q9BRR6,P04062,P67812,Q6NUQ4,Q5J8M3,Q8TCT9,Q15363,Q07812,Q9Y2G5,Q9H0U3,O75844,O00461,Q8NBZ7,Q9P2W9,O95470,Q9H3N1,Q86YN1,Q9Y5M8,Q9HD20,Q9HC07,O95249,O15127,Q96AG4,P51648,O60762,Q8TCJ2,O60725,Q9Y394,Q8TB61,P57088,Q9Y2B2,Q16850,Q8IY17,P40616,P06493,Q86XL3,O15027,Q92604,Q96AA3,O95864,Q5T9L3,Q96KC8,P27544,Q15041,P35613,Q15382,O95197,P51151,P05067,Q9BUN8,Q13438,Q15800,Q9UKU0,Q70UQ0,O75298,P38435,Q96G23,Q9NQC3,P07099,O43464,Q96A33,Q9BZG1,Q8N2K0,Q8TCT8,Q07065,O60499,Q10713,O43292,O95070,Q9UBV2,Q9GZP9,O43852,O15269,Q96HY6,Q96JJ7,Q9P035,Q6P179,Q9NPA0,Q9NPR9,Q8N5M9,P50402,P09496,Q14534,Q10472,Q9BVK6,Q9BVG9,Q99735,Q15392,P46977,P49755,Q96N66,O75845,O14681,P20073,Q96S66,Q9H6H4,Q9Y3A6,Q9NX62,Q9BQT9,Q13190,P01889,Q86Y07,P51572,Q99720,P61019,Q9H4A5,P16435,Q14739,Q8WVQ1,Q9H4A6,Q969X5,Q99442,Q86UL3,O95674,Q4J6C6,Q8NHH9,Q96PC5,Q9Y6I9,Q86UE4,Q9NZ08,O15126,A1L0T0,P51571,P10321,P98194,Q9BU23,Q9Y4P3,P0CG08,Q53GQ0,Q6NUM9,O75915,P04843,Q12981 | Localization | GO Cellular component | msigdb_gocc | 4,5,6,509,8,9,14,520,17,534,529,540,541,30,538,38,39,40,546,547,46,47,561,53,54,55,565,566,577,60,64,65,66,67,586,70,71,74,585,584,77,81,601,607,606,86,93,94,97,98,614,100,103,109,113,114,125,638,130,633,647,132,651,135,644,662,145,657,654,653,154,652,674,675,670,165,166,164,169,170,680,173,678,175,177,692,182,188,194,199,200,210,213,216,218,221,224,222,223,229,237,242,243,248,262,261,263,271,280,298,300,296,303,308,311,310,309,318,324,336,335,334,346,342,355,364,361,367,369,372,385,394,392,390,388,396,404,411,414,418,419,422,424,430,433,431,432,429,435,437,438,439,441,446,447,442,449,450,454,460,461,469,463,480,490,493,500,502 | 1253,449,3153,38,1727,2764,93,2658,1041,766,2441,2738,2739,3189,367,529,1128,1406,1168,652,442,125,39,271,1656,1800,243,218,17,2659,60,2872,263,844,1932,237,1511,132,633,1583,1898,199,828,1094,1107,2922,86,361,493,716,1130,1238,1215,1934,1586,248,173,114,1839,98,1588,1763,2000,435,54,670,1935,1255,894,396,71,546,500,1289,175,653,216,2368,1412,309,40,463,454,2232,2328,1218,422,538,690,369,914,3281,2062,3050,4,1733,164,1902,856,3100,3009,1973,14,1156,1974,1045,1595,783,170,1064,200,1807,654,1321,30,2414,342,1047,2183,520,1879,6,565,1220,355,310,1346,678,1491,450,411,130,566,1135,547,2852,3119,2093,2338,2185,644,1845,2445,2094,1387,2009,720,418,990,991,2577,2037,2187,3336,1264,1493,1633,1634,899,1883,1736,74,1668,2688,460,1225,509,1635,2015,3368,859,1459,1324,1669,229,601,2189,1267,879,324,2580,242,1671,732,2133,502,388,692,956,540,1034,2481,5,1069,2134,318,1325,424,1422,55,2422,934,935,169,2451,1776,9,1673,81,680,346,1528,1082,65,1952,182,1036,1850,1142,145,795,437,480,66,584,758,165,3158,823,813,994,541,490,2103,585,296,2041,1919,194,1160,796,446,429,997,154,404,100,47,1427,2020,657,8,3188,586,222,67,900,311,1498,1822,1309,94,835,939,438,1163,2454,135,561,1272,647,2588,223,77,1747,836,1985,430,3217,1020,1640,2625,674,2548,1184,1784,1230,2431,431,221,675,638,1959,800,210,1377,280,1089,298,166,364,439,1249,1534,372,432,1891,1856,414,334,2862,904,53,390,70,785,1857,534,869,1470,461,177,942,335,336,924,577,1433,1278,3109,224,1681,261,3110,606,762,1828,614,419,433,1474,385,1988,2113,113,1335,109,1435,303,308,213,3252,1152,738,1279,2026,392,1280,1123,447,1793,300,778,1867,1312,2395,97,2435,3061,1477,968,262,803,1189,1166,188,1127,1211,1284,2055,1690,46,1929,662,607,854,651,1545,394,2870,469,103,872,64,1442,3138,1695,873,441 | 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| 3,381 |
Intrinsic component of organelle membrane | 68 | 140 | 6.950076 | 0 | O60830,O14925,Q9GZP9,P49069,Q99595,Q8TB61,Q15125,Q9BPX6,P42892,P01889,Q9Y2R0,Q9BWH2,Q9H9P8,Q86XL3,Q5XKP0,Q6ZRP7,Q9H3K2,P51572,Q9NX63,O15118,Q5T9L3,O75880,Q13505,Q15041,Q9P035,Q14739,P20339,Q9GZY8,Q9Y282,Q9NPA0,Q969X5,Q9BUN8,O43505,L0R6Q1,Q99442,O43752,Q9Y287,Q6UXV4,O15126,Q9Y5Y5,Q15629,Q9UG56,O75298,Q9NWR8,P17152,P10321,P98194,Q8TCT9,Q9Y4P3,Q6P4A7,Q7L0J3,Q9NQC3,O75844,Q5HYI7,Q8IWA4,Q96A33,Q8TCT8,O95470,Q86YN1,P61020,Q8N8Q8,O60499,P57105,O43808,O43292,O95070,Q15388,O15258 | Localization | GO Cellular component | msigdb_gocc | 0,131,261,6,7,135,9,268,140,396,15,401,19,154,281,283,284,411,291,286,165,421,168,169,300,424,295,426,46,303,431,177,305,179,432,60,189,445,442,64,65,322,199,459,455,454,460,77,469,83,340,213,86,91,348,221,223,98,100,228,231,237,110,360,243,248,250,383 | 1253,179,766,131,1168,286,442,383,243,305,60,360,1028,237,0,199,1061,86,421,716,1761,595,248,98,829,642,396,546,454,728,596,455,989,1732,295,1902,856,1973,2666,140,6,2070,571,876,411,1223,644,110,228,2187,460,1066,859,1459,879,502,168,2134,424,935,169,834,9,1424,250,65,1227,1142,1158,861,1100,91,584,1916,165,281,83,445,283,340,997,154,784,100,348,1037,1203,1498,231,1639,748,1746,135,223,77,1273,1184,1230,431,221,715,1534,432,7,268,1857,750,474,177,401,261,426,284,736,19,1335,303,213,2703,888,459,291,1123,300,778,2395,1477,322,1313,984,1211,46,189,15,1076,469,765,591,64,1695 | 0.0675175531380731,1.8034993850372483,0.49814935110308256,1.995686459291915,0.128824213397895,1.3500839456990343,0.9923523595397633,1.1226055097209044,1.5091181530837137,1.3002814037400503,2.717957874901268,1.1611295689133987,0.24955044852133723,1.5452220568165775,4.174427463103442,1.7108706217957421,0.21960063359485635,2.393772583906324,1.031729958547143,0.5551489958059633,-0.18432557342032058,0.736682872551653,1.4970346589149368,2.235562824872222,0.4116024166954531,0.667521468415162,1.0838294064395717,0.8050436732526357,0.9659543529438528,0.5409506773670444,0.736682872551653,0.9659543529438528,0.27934845246757406,-0.1682642630641737,1.325234886963656,-0.24901515263246263,0.38246844551024856,-0.281630105291349,-0.6355492145278823,1.9398001945208163,3.8479234632840806,-0.33089608510881563,0.7641221963157447,0.367847206626791,1.057836964111845,0.09825091479754514,0.667521468415162,2.160276723233794,1.5811082112453032,-0.39723658082010016,0.9527110641842556,0.21960063359485635,0.38246844551024856,-0.04133497065359173,0.367847206626791,0.8726226873579839,1.8378675573382266,-0.3639722106197193,1.031729958547143,0.3237642470959609,1.8378675573382266,0.4116024166954531,3.790384154242022,-0.0256603710645763,1.472793767169314,2.658490686895177,0.09825091479754514,0.15923915280621745,0.14405137258271195,0.38246844551024856,0.18949740958903347,2.3414986895471337,0.7504184690468082,-0.24901515263246263,1.8492797575498616,1.3748294740816678,2.424919578143314,0.9923523595397633,1.3624695957539459,1.2121086826797591,0.27934845246757406,1.8720388877331144,0.4838128792612018,2.235562824872222,1.1994049280050039,0.24955044852133723,0.11355746484162065,-0.05705159094963218,1.5811082112453032,-0.12034295190828731,0.5267180776783301,-0.1682642630641737,1.9845509548727378,1.6049126688329458,2.527590393054582,0.0675175531380731,0.128824213397895,0.09825091479754514,1.0186331693037094,1.6167792983058513,0.5693132022609276,-0.07281046412115222,1.0186331693037094,3.839736848219882,1.4240134588486117,-0.21658099121495536,0.5267180776783301,0.9261352342099904,1.8149774576557305,1.0838294064395717,1.4484536466130733,1.031729958547143,1.3624695957539459,0.5409506773670444,3.5201705266631,0.036622396653028605,1.3127712547525017,1.640441843029371,-0.6529499285349974,0.367847206626791,0.9659543529438528,1.3500839456990343,0.17438776279080853,1.325234886963656,0.49814935110308256,-0.4812357112409115,-0.04133497065359173,1.2500575283842046,0.052090308590681936,0.29419101786197954,0.11355746484162065,2.9690677810146133,1.7689320262511543,3.605912530010354,0.21960063359485635,0.9394380703588899,0.512451026199518,0.7504184690468082,2.6783785011395778,-0.1362731975345778 | 3,381 |
Nuclear outer membrane endoplasmic reticulum membrane network | 143 | 331 | 6.937516 | 0 | 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| Localization | GO Cellular component | msigdb_gocc | 4,5,6,8,9,14,520,17,534,540,541,30,538,38,39,40,546,46,47,53,54,55,565,566,64,65,66,67,586,70,74,585,584,77,81,601,607,606,86,97,98,614,100,103,109,638,130,633,647,132,651,648,135,644,662,145,657,653,154,652,674,675,670,165,166,164,169,170,680,173,678,177,692,182,188,194,199,200,210,213,216,218,221,222,223,229,243,248,262,261,263,271,280,298,300,296,303,311,310,318,324,336,335,334,346,342,355,364,361,367,369,372,385,394,390,388,396,404,411,414,418,422,424,430,431,432,429,435,438,439,441,446,447,449,450,454,461,469,480,490,493,500,502 | 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| 3,381 |
Transporters | 160 | 389 | 6.930745 | 0 | 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| Functions | Protein Atlas Protein class | protein_atlas_protein_class | 511,4,5,6,507,524,12,522,518,533,20,528,529,540,542,31,538,34,35,36,37,39,546,42,43,44,560,561,49,555,554,52,565,55,568,577,60,64,65,66,67,68,571,591,584,76,580,79,81,601,83,606,86,597,92,596,595,599,614,613,104,620,105,623,109,110,618,617,113,628,119,625,125,638,647,135,644,643,139,642,653,155,664,158,675,165,167,671,170,682,175,697,177,692,189,195,699,193,712,217,221,223,229,231,235,233,251,262,261,268,277,276,286,294,298,299,303,306,309,323,326,338,349,348,342,355,359,365,364,360,367,371,372,379,376,374,383,384,388,397,411,414,417,432,438,439,442,443,457,459,460,465,474,483,498,492,493,500,513,516 | 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Organelle inner membrane | 119 | 258 | 6.011869 | 0 | O60830,Q99595,Q9UDW1,P20674,Q9Y2R0,Q9UDX5,P00846,Q9H9P8,O43676,Q69YU5,P06576,O75964,P00403,Q70HW3,P62995,Q9H2D1,P22830,Q16540,Q9UBX3,O43615,Q7Z7F7,O95298,Q9Y5L4,Q9Y512,Q9NPL8,Q6P4A7,O95831,O75844,Q5HYI7,O14949,O94901,Q9Y619,O95202,P03886,P22695,P15954,P10606,Q13423,Q5T9A4,Q567V2,P56385,O14925,P14406,O96008,Q9BSK2,Q6DKK2,P56378,Q9H1E5,O43772,Q9H061,P12236,Q9H2V7,Q9Y2C4,Q9NX14,Q13505,Q8N183,Q6NUK1,P18031,O95168,Q86Y39,Q9BRJ2,Q9Y5J9,P13073,Q02978,Q96NB2,P14927,Q8NI60,P24539,Q9P015,Q8NBN7,Q9H9B4,O60220,Q9BRT2,P12235,Q8N8Q8,Q9BTV4,Q8NE86,Q03252,Q9Y4W6,Q10713,P23786,P20700,O14548,Q96CU9,Q9BPX6,P82933,Q5XKP0,Q9H3K2,Q9NX63,Q9Y6C9,Q9BQT8,P50402,O75208,Q9UG56,P10909,Q3ZCQ8,P36542,Q9NQ50,Q9NVI7,Q8IYU8,O75438,O75306,P09669,Q99720,O75880,P36551,Q14739,O95674,Q9Y5J7,Q6UXV4,O60313,Q9NWR8,P17152,Q9BUB7,O75489,Q9H936,P53701,P56134,Q96IX5 | Localization | GO Cellular component | msigdb_gocc | 0,7,11,518,15,16,18,19,22,23,530,27,31,34,549,35,41,558,42,553,56,569,592,591,590,83,84,86,91,89,595,104,105,106,107,618,617,117,637,121,634,131,138,642,139,142,143,148,664,158,671,167,687,686,168,683,682,690,689,186,705,190,193,712,715,708,202,204,725,723,736,219,735,728,231,750,748,745,765,242,756,755,752,267,268,270,281,284,291,294,299,310,317,322,328,339,353,366,382,379,402,408,409,414,421,423,424,435,440,445,443,459,455,474,487,498,494,501,505 | 911,752,131,89,553,767,22,664,1028,219,443,0,1317,317,1449,408,1079,1061,402,1968,487,2327,1622,845,86,421,912,27,2227,595,689,1624,105,569,1899,829,435,84,1029,642,31,18,106,1411,986,530,3193,2031,949,3006,2293,409,617,2803,328,728,671,2369,193,138,708,618,455,1367,690,3037,518,755,820,2475,107,41,2233,756,204,1700,3294,1939,2610,1451,1046,353,423,2666,2333,2477,953,791,1111,2926,2416,1770,3273,2070,310,1906,877,2071,1295,494,1943,2501,501,143,634,858,2532,549,2014,1494,2503,3075,1417,1458,1773,270,1066,712,745,242,1524,932,1014,2307,117,168,1246,1461,424,834,1227,558,2243,1425,1158,339,861,1100,121,91,2969,1916,2102,637,281,23,142,682,1050,83,445,1305,34,2912,56,1306,186,379,683,1229,1530,231,1499,723,1639,807,748,202,921,3347,1183,1185,1607,2045,267,1375,3284,2814,1608,1376,1053,505,715,883,7,776,414,268,1055,299,705,735,139,750,1431,474,2516,1723,925,1962,1472,2084,158,148,35,167,1025,284,2112,498,736,2433,19,1233,1829,2593,590,366,2703,817,2733,1685,888,382,1403,459,686,291,3163,725,2053,2734,42,11,16,322,984,970,1104,1544,687,1105,15,2523,2657,1076,2494,1756,1167,1285,765,591,440,190,592,104,294,841 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| 3,381 |
Mitochondrial envelope | 151 | 338 | 5.929421 | 0 | 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| Localization | GO Cellular component | msigdb_gocc | 0,2,7,11,13,518,15,16,18,19,22,23,530,27,29,31,34,35,36,38,40,41,42,558,44,553,56,569,571,592,591,590,588,73,587,601,83,84,91,89,104,102,105,106,107,110,618,617,632,115,117,121,637,634,131,650,138,139,642,142,143,664,665,668,158,167,671,683,163,168,687,686,682,178,690,689,186,188,705,190,193,712,715,708,202,204,208,725,723,736,218,219,735,728,226,227,231,748,765,242,756,250,752,773,267,268,270,278,281,284,291,294,299,317,322,328,339,348,353,359,366,382,381,379,401,404,402,408,409,421,423,426,433,435,440,445,444,443,453,459,455,474,483,484,487,488,498,494,501,502,505 | 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Transmembrane transport | 109 | 232 | 5.631839 | 0 | O60830,Q9NS69,P05023,Q99595,Q96PU5,Q9UDW1,P20674,P21796,P00846,P06576,O75964,Q8NE01,P00403,P16615,Q70HW3,Q9H2D1,P45880,Q9UBX3,Q9C0H2,Q6P4Q7,P51798,O43615,Q9Y5Y5,P50416,Q15629,P04062,Q9UHG3,Q6P4A7,O95831,Q9H0U3,O75844,Q07812,P28288,Q8WTV0,P61421,Q99808,Q9Y619,O95202,Q9HD20,P10606,Q9HC07,Q13423,O60831,P56385,O14925,Q8TB61,P05026,O96008,Q9BSK2,O43772,P52789,P12236,Q9H2V7,Q15041,Q6NUK1,P05067,Q9Y289,Q9Y277,L0R6Q1,P13073,Q02978,Q96NB2,O75298,P38435,P62258,P24539,Q9Y251,Q9H9B4,Q96QD8,Q15758,P12235,Q9Y6M7,Q8NE86,P30825,Q9Y4W6,P23786,Q15388,Q8NEW0,O14548,Q9BPX6,P27105,Q9BQT8,P53985,P31751,Q3ZCQ8,Q7L0J3,P36542,P49755,O43808,P22413,Q8IYU8,P08183,O75381,P51790,Q9UMX0,P46934,P31749,Q99442,P0DP25,Q8IXU6,Q9NWR8,P98194,Q16625,P0CG08,Q07820,Q9H936,O75915,O95747,P56134 | Processes and pathways | GO Biological process | msigdb_gobp | 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| 3,381 |
Ion transmembrane transporter activity | 59 | 102 | 5.576561 | 0 | P56385,P05023,Q8TB61,P05026,Q9UDW1,P21796,P20674,P00846,P06576,O43772,O75964,P00403,P16615,Q70HW3,Q9H2D1,P45880,P12236,Q9BQT8,Q9UBX3,Q9C0H2,Q6P4Q7,Q6NUK1,Q9Y289,P51798,Q9Y277,Q9Y487,P13073,Q02978,Q96NB2,P53985,Q9NWR8,P24539,P98194,Q93050,Q6P4A7,Q9H0U3,P0CG08,Q9H9B4,Q96QD8,Q15758,P61421,P12235,P36542,Q99808,Q9Y619,O95202,Q9Y6M7,P30825,Q9HD20,O43808,P10606,Q9H936,Q9HC07,O43681,Q96S66,Q13423,P56134,Q8NEW0,P51790 | Functions | GO Molecular function | msigdb_gomf | 634,507,135,643,11,13,518,18,530,664,27,31,538,34,35,36,671,299,42,43,560,682,697,555,178,63,193,712,715,323,459,204,460,79,83,606,463,736,217,734,599,728,353,613,104,105,235,233,109,360,617,498,113,492,372,117,501,251,377 | 2146,752,492,664,360,845,912,27,105,829,31,18,507,643,986,530,2403,1042,913,949,463,617,728,671,193,538,989,518,1594,3008,13,204,1700,233,2610,1843,353,1109,2374,2746,36,1111,2926,377,555,1295,323,878,501,634,599,2187,460,1066,993,712,117,1461,1562,734,849,3353,682,2041,83,560,34,748,251,135,1747,2841,79,2210,715,217,372,613,299,942,43,606,35,1232,498,736,113,109,1279,459,42,11,1542,970,1211,178,697,63,1153,104,3029,235 | -0.380580727609994,0.512451026199518,0.886046284757872,0.6396283914658812,1.1611295689133987,0.3970534541929916,0.3384952950336184,3.3360620594700903,2.192658207659924,0.4116024166954531,3.228285933657418,3.5287995182001897,0.8591685467310516,0.667521468415162,0.27934845246757406,0.8321680621038776,-0.4981815098100403,0.23459461671822154,0.3384952950336184,0.3089962184714941,0.9394380703588899,0.7091154600079058,0.5409506773670444,0.6256322496638714,1.7341630938766759,0.81862142870259,0.27934845246757406,0.8456837197085607,-0.10445590752084172,-0.8840205662190869,3.665218562873702,1.6874867509018345,-0.1522468865249289,1.5691701875504565,-0.6009028178865126,-0.21658099121495536,1.1866739046641297,0.17438776279080853,-0.4812357112409115,-0.6879079811712451,3.173668490790479,0.17438776279080853,-0.8119401366404397,1.1354747011565787,0.7914346484543726,0.052090308590681936,1.2374348642931197,0.367847206626791,0.8726226873579839,0.6814187237709133,0.736682872551653,-0.39723658082010016,0.9527110641842556,0.21960063359485635,0.27934845246757406,0.5693132022609276,2.1059150941587093,-0.04133497065359173,-0.088611824283511,0.5409506773670444,0.3970534541929916,-2.2704910421618587,0.6116028235314318,-0.3144279325201492,2.424919578143314,0.7914346484543726,3.191929224701824,0.5267180776783301,1.472793767169314,1.9845509548727378,-0.1682642630641737,-0.7407414914126782,2.4969731427236144,-0.39723658082010016,0.5693132022609276,1.6286223242764093,1.1483160129394345,0.7229152541390564,1.325234886963656,0.3237642470959609,3.0255595862775544,0.736682872551653,3.191929224701824,0.09825091479754514,0.886046284757872,0.5409506773670444,2.138591310737635,2.1710900300592053,0.0675175531380731,0.9659543529438528,3.034923654113158,3.7072278486138166,-0.07281046412115222,0.3089962184714941,0.11355746484162065,1.8149774576557305,0.5975399499868604,2.6783785011395778,0.15923915280621745,2.203413222336374,-0.8840205662190869,1.5691701875504565 | 3,381 |
Golgi membrane | 56 | 143 | 5.533939 | 0 | P24390,Q14108,Q8TB61,Q9BQT9,O15498,Q13190,P01889,O43731,Q9H9S5,Q16739,Q6ZRP7,P51572,P61019,Q9H4A5,Q5T9L3,O95721,P04439,O15260,P35613,Q9H4A6,O95197,Q9Y282,Q8IV08,Q8TBA6,O43505,Q969X5,L0R6Q1,O60476,P49257,Q8IZA0,O43752,Q9Y287,Q10472,Q9BVK6,P33908,P10321,P98194,Q8NCH0,Q92896,Q15363,Q7LGA3,P0CG08,Q15392,O00461,Q9P2W9,P49755,O60499,Q9HC07,Q10713,O95249,Q96S66,Q8NDZ4,O95070,Q9Y3E0,P51790,O15258 | Localization | GO Cellular component | msigdb_gocc | 4,5,135,390,386,388,396,17,273,20,283,411,418,419,165,415,546,39,170,433,173,46,47,561,305,431,179,434,565,57,60,189,324,336,75,454,460,78,468,81,209,463,346,93,97,355,237,113,242,114,372,504,248,517,377,383 | 179,93,2738,2678,652,383,39,386,305,17,2659,60,434,237,1583,1094,248,173,114,415,894,396,546,1412,463,454,2328,2150,914,2062,4,75,1595,170,2902,654,1321,1047,1879,565,355,1346,678,411,377,1135,2852,3119,2093,1845,2094,1387,2009,418,990,991,1264,1179,628,1388,1668,460,2189,1267,879,324,2580,242,732,388,956,1911,5,1422,2933,1673,81,680,346,1528,1850,20,1142,165,283,209,796,2835,938,784,1180,47,57,2837,865,78,504,835,135,561,901,1985,1640,2548,468,431,1089,372,1856,1206,390,336,1610,577,1433,762,659,419,433,884,1988,273,113,964,1862,738,1280,1867,97,2435,3061,2116,3302,1127,1211,46,189,1929,2918,3223,1191,517,3138 | 1.8034993850372483,2.3204608262891933,-0.6879079811712451,-0.6529499285349974,0.6535914108187438,1.1226055097209044,3.081527209308513,1.109708313950368,1.3002814037400503,3.546020725355962,-0.6355492145278823,2.717957874901268,1.0055073471610068,1.5452220568165775,-0.10445590752084172,0.18949740958903347,1.4970346589149368,1.8149774576557305,2.116827011264163,1.0447978465606236,0.35318955209666003,1.0838294064395717,0.8050436732526357,-0.0256603710645763,0.9394380703588899,0.9659543529438528,-0.46433895531968433,-0.380580727609994,0.3384952950336184,-0.33089608510881563,3.929188844143836,2.537761544739181,-0.10445590752084172,1.8264334861453515,-0.794058677274936,0.6535914108187438,0.036622396653028605,0.23459461671822154,-0.2327756018219659,0.7777942059504881,1.1866739046641297,0.021113596394116325,0.6116028235314318,1.057836964111845,1.1354747011565787,0.15923915280621745,-0.7584596965728567,-0.9938445474628532,-0.34741075419628276,-0.21658099121495536,-0.34741075419628276,-0.01002756193935577,-0.2980060279588005,1.0447978465606236,0.27934845246757406,0.27934845246757406,0.0675175531380731,0.128824213397895,0.6952833352363743,-0.01002756193935577,-0.1362731975345778,0.9527110641842556,-0.39723658082010016,0.0675175531380731,0.367847206626791,1.2374348642931197,-0.5836565067512672,1.521177149662278,0.5409506773670444,1.109708313950368,0.3089962184714941,-0.24901515263246263,3.8560990647949103,-0.0256603710645763,-0.8119401366404397,-0.1362731975345778,2.445594751613174,0.6116028235314318,1.1994049280050039,-0.07281046412115222,-0.21658099121495536,3.511529228585786,0.15923915280621745,1.8492797575498616,1.3624695957539459,1.6640107410606462,0.4694414362325219,-0.7407414914126782,0.3237642470959609,0.4838128792612018,0.128824213397895,2.9596008068193096,2.8060706855393898,-0.7407414914126782,0.38246844551024856,2.4969731427236144,0.8726226873579839,0.4116024166954531,1.9845509548727378,0.7914346484543726,0.35318955209666003,-0.281630105291349,-0.12034295190828731,-0.5664610395431358,0.9394380703588899,1.0186331693037094,0.2045682986016007,1.1483160129394345,-0.21658099121495536,0.11355746484162065,1.109708313950368,1.2247852884525057,-0.10445590752084172,0.7641221963157447,-0.0256603710645763,0.512451026199518,0.6535914108187438,1.0447978465606236,1.0186331693037094,0.367847206626791,-0.281630105291349,1.3994723547109182,2.138591310737635,0.3089962184714941,-0.21658099121495536,0.5409506773670444,0.0675175531380731,-0.21658099121495536,2.2781622213637456,-0.4981815098100403,-0.9203985222019436,-0.34741075419628276,-1.5357759674833416,0.17438776279080853,0.11355746484162065,2.9690677810146133,1.7689320262511543,-0.24901515263246263,-0.794058677274936,-1.1816287398654612,0.128824213397895,0.8591685467310516,-1.0123520190468205 | 3,381 |
Mitochondrion organization | 93 | 202 | 5.306546 | 0 | O60830,Q9NS69,Q99595,Q16543,P21796,Q9Y2R0,Q9UDX5,O43676,Q69YU5,Q8N4H5,P45880,P53365,Q04837,O43615,P49257,O95298,Q9Y5L4,Q9Y512,P04062,Q96A26,Q07812,O95831,Q5HYI7,Q9Y3B8,O95202,P03886,Q9NQ88,P30536,Q5T9A4,O75153,O14925,Q9NVT9,O14737,P14406,O96008,Q9BSK2,Q9Y2S7,Q6DKK2,P55786,P52789,Q9H061,Q8N183,P27544,Q9NX14,Q13505,Q9BZL1,Q5JRX3,O95168,Q86Y39,Q9Y5J9,O43464,O60220,Q9UII2,Q9BRT2,P12235,Q8N8Q8,Q8NE86,P49841,Q9Y4W6,Q10713,Q15388,O14548,Q99623,O95429,Q96CU9,Q8N2A8,Q5XKP0,Q9H3K2,Q9NX63,Q9Y6C9,Q9NUQ9,Q9UG56,P10909,Q3ZCQ8,Q8IWA4,Q9NVI7,Q9BWH2,O75438,O75306,P51572,P31749,O75880,Q9GZY8,Q9H4A6,Q9Y5J7,Q6UXV4,P0DP25,O60313,P17152,Q9BUB7,Q8N5M1,O75489,Q13501 | Processes and pathways | GO Biological process | msigdb_gobp | 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Transporter | 85 | 196 | 5.245286 | 0 | Q13277,Q00765,P05023,P24390,O43731,P00846,P06576,Q13445,Q6NUK4,P16615,Q70HW3,Q9H2D1,Q9UBX3,P11279,Q9BQE5,P49257,P51809,O43752,Q9Y487,Q93050,Q15363,Q9H0U3,P28288,P13473,P61421,Q9P2W9,Q99808,Q9Y619,P54105,O95202,Q9C0E2,Q9HC07,O95249,P56385,Q8TB61,P05026,O96008,Q9BSK2,O43772,P17900,Q9HD45,P12236,Q9H2V7,Q6NUK1,Q9Y289,O60749,Q02978,O43760,Q96NB2,P24539,Q9H9B4,Q96QD8,Q15758,P12235,Q9Y6M7,P30825,O60499,Q15388,Q8NEW0,Q9Y6C9,Q9BQT8,P09496,P53985,Q92973,Q9BVK6,Q7L0J3,Q8NFH4,P36542,P49755,Q9NZJ7,Q99805,O43808,Q8N1F7,P08183,Q92544,Q9H6H4,Q9Y3A6,Q13190,P51572,O95721,Q8IXU6,P98194,O15400,Q9H936,P56134 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 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Endoplasmic reticulum | 81 | 205 | 5.121847 | 0 | Q00765,Q8N0U8,Q15125,P48651,O43731,Q9BT22,P43307,P13674,O00264,O15260,Q8IV08,P49257,Q14849,Q5BJF2,Q6NUQ4,Q8TCT9,Q14696,Q9P2W9,Q9H3N1,Q14257,P35790,O95470,O60831,O96005,Q96AG4,P51648,Q8TCJ2,Q92791,Q16850,Q8IY17,O15027,Q86XL3,Q5T9L3,Q96KC8,P27544,O43169,Q15041,Q15293,O95197,Q9BUN8,Q96CN7,Q9Y680,Q13438,Q15800,Q70UQ0,Q96G23,Q9NQC3,Q96A33,P67809,O43292,Q9H3G5,Q9GZP9,Q96KA5,O43852,O15269,Q96HY6,Q9P035,P50402,Q99735,P84157,Q9NR31,Q8WUJ1,O75845,O14681,Q96S66,Q9H0P0,Q9H6H4,Q86Y07,P51572,Q99442,O95674,Q8NHH9,Q96PC5,Q86UE4,P51571,P0CG08,O15460,O75915,P04843,Q12981,Q6UW68 | Localization | Protein Atlas Subcellular | protein_atlas_subcellular_location_all | 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| 3,381 |
Golgi apparatus | 104 | 335 | 5.115505 | 0 | P50897,P24390,Q14108,P05023,Q96PU5,O43731,Q16739,P80303,O14828,Q13445,P53634,O15260,P04439,P53365,Q9Y282,Q8IV08,Q8TBA6,P49257,P51809,Q8IY95,Q8IZA0,O43752,P04062,P33908,Q5VW38,Q8NCH0,Q93050,Q15363,O75503,O14773,O00461,Q8NBZ7,Q9P2W9,Q9HC07,O95249,O15127,Q7RTS9,Q8TB61,Q68CQ7,Q9NQX7,Q5T9L3,P35613,O95197,P05067,L0R6Q1,Q9Y287,Q8NEY8,Q7LGA3,Q9BZG1,O60499,Q10713,O95070,Q8NEW0,P06280,O95456,O43852,Q9H9S5,Q8N2A8,Q6ZRP7,Q9NX40,O15118,O43505,Q9NPR9,P09496,Q10472,Q9BVK6,Q8N3R9,P10909,Q9NR31,Q15392,P49755,Q92542,Q99805,O14681,Q96S66,P51790,O15258,Q92544,Q9Y3A6,Q9NX62,Q9BQT9,O15498,Q13190,P01889,P46934,P16278,P51572,P61019,Q9H4A5,O95721,Q92520,Q8WVQ1,Q9H4A6,Q969X5,O60476,Q4J6C6,O15126,P10321,P98194,Q92896,P0CG08,Q9UQB8,Q8NDZ4,Q9Y3E0 | Localization | GO Cellular component | msigdb_gocc | 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| 3,381 |
Ion transport | 95 | 219 | 5.047068 | 0 | Q15907,P05023,Q96PU5,O15173,Q9UDW1,P20674,P21796,P00846,P06576,O75964,Q8NE01,P00403,P16615,Q70HW3,Q9H2D1,P45880,Q9UBX3,Q9C0H2,Q6P4Q7,P07602,P51798,P51809,P14174,Q9UHG3,Q6P4A7,Q9H0U3,Q07812,O75844,P28288,P61421,Q99808,Q9Y619,P54105,O95202,Q9HD20,P10606,Q9HC07,P30536,Q13423,O60831,P56385,Q8TB61,P05026,O96008,O43772,P12236,Q15041,Q6NUK1,P05067,Q9Y289,Q9Y277,P13073,Q02978,Q96NB2,P62258,P24539,O76024,Q9H9B4,Q96QD8,Q15758,P12235,Q9Y6M7,Q8NE86,P30825,Q9Y4W6,Q9H0H5,Q8NEW0,O14548,Q9BPX6,P27105,Q9BQT8,P53985,P24941,Q08722,Q7L0J3,P36542,Q9NZJ7,O43808,P22413,Q96S66,Q8IYU8,P08183,P51790,Q9UMX0,P46934,P31749,P0DP25,Q9NWR8,P98194,P0CG08,Q9H936,O43681,O75915,O95747,P56134 | Processes and pathways | GO Biological process | msigdb_gobp | 512,507,525,10,11,518,13,18,530,27,542,31,538,34,35,36,42,43,560,49,555,566,61,82,83,606,601,86,597,599,613,104,620,105,109,617,113,115,117,625,634,135,643,642,664,671,169,682,175,697,178,193,712,715,710,204,716,736,217,734,728,235,748,233,765,761,251,752,268,276,299,323,329,338,340,353,359,360,370,372,379,376,377,393,397,417,444,459,460,463,498,492,493,499,501 | 2557,2146,1727,911,752,2739,1193,10,492,1547,664,360,844,2850,625,1317,3004,1449,3031,1968,845,86,493,912,27,716,105,829,499,642,31,18,1803,2030,2632,507,643,175,986,1661,530,2403,3034,49,2031,1042,376,913,949,463,444,617,2232,2743,1970,728,671,193,1731,61,538,2002,1367,2828,989,1732,518,1594,3008,3281,13,370,204,329,1700,276,3202,2330,597,3115,115,1156,233,417,2610,789,1843,952,1519,353,1109,2374,2746,2035,36,2414,397,2181,1111,2926,1346,377,555,566,1295,323,620,931,822,878,501,634,1224,599,2037,2187,710,899,2267,1013,992,460,1066,993,1225,1522,712,2131,1067,601,1137,338,3076,1299,2133,1525,117,1034,880,1461,1562,1462,169,2451,1673,919,734,512,1425,849,3353,682,2041,83,560,1919,34,340,2020,379,1309,542,748,251,135,1747,2841,2210,1377,715,525,217,372,3219,776,1206,613,1535,904,268,299,1000,942,3343,43,761,606,2675,35,1232,2217,498,736,113,109,964,2733,1279,459,359,42,11,2116,82,1542,970,1104,1211,393,2960,818,178,697,1692,2284,765,104,3029,235 | 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| 3,381 |
Cation transmembrane transporter activity | 42 | 70 | 4.885958 | 0.000001 | P56385,P05023,P05026,Q9UDW1,P20674,P00846,P06576,O43772,O75964,P00403,P16615,Q70HW3,Q6P4Q7,Q9Y289,Q9Y487,P13073,Q96NB2,P24539,P98194,Q93050,Q9H0U3,Q9H9B4,Q96QD8,Q15758,P61421,P12235,P36542,Q99808,Q9Y619,O95202,Q8NE86,P30825,Q9Y6M7,O43808,Q9HD20,P10606,Q9H936,Q9HC07,P56134,Q13423,Q8NEW0,P51790 | Functions | GO Molecular function | msigdb_gomf | 634,507,643,11,518,18,530,664,27,31,538,34,560,697,63,193,715,204,460,79,606,736,217,734,599,728,353,613,104,105,748,233,235,360,109,617,498,113,501,117,251,377 | 752,664,360,912,27,105,31,18,507,643,986,530,2403,1042,913,949,617,728,193,538,989,518,1594,3008,204,1700,233,2610,353,1109,2374,1111,2926,377,878,501,634,599,2187,460,1066,993,117,734,849,560,34,748,251,2841,79,2210,715,217,613,606,1232,498,736,113,109,1279,11,1542,1211,697,63,1153,104,235 | 0.512451026199518,0.6396283914658812,1.1611295689133987,0.3384952950336184,3.3360620594700903,2.192658207659924,3.228285933657418,3.5287995182001897,0.8591685467310516,0.667521468415162,0.27934845246757406,0.8321680621038776,-0.4981815098100403,0.23459461671822154,0.3384952950336184,0.3089962184714941,0.7091154600079058,0.5409506773670444,1.7341630938766759,0.81862142870259,0.27934845246757406,0.8456837197085607,-0.10445590752084172,-0.8840205662190869,1.6874867509018345,-0.1522468865249289,1.5691701875504565,-0.6009028178865126,1.1866739046641297,0.17438776279080853,-0.4812357112409115,0.17438776279080853,-0.8119401366404397,1.1354747011565787,0.367847206626791,0.8726226873579839,0.6814187237709133,0.736682872551653,-0.39723658082010016,0.9527110641842556,0.21960063359485635,0.27934845246757406,2.1059150941587093,0.5409506773670444,0.3970534541929916,0.7914346484543726,3.191929224701824,0.5267180776783301,1.472793767169314,-0.7407414914126782,2.4969731427236144,-0.39723658082010016,0.5693132022609276,1.6286223242764093,0.7229152541390564,0.736682872551653,0.09825091479754514,0.886046284757872,0.5409506773670444,2.138591310737635,2.1710900300592053,0.0675175531380731,3.7072278486138166,-0.07281046412115222,0.11355746484162065,0.5975399499868604,2.6783785011395778,0.15923915280621745,2.203413222336374,1.5691701875504565 | 3,381 |
Anion transport | 44 | 73 | 4.832775 | 0.000001 | Q15907,Q8TB61,P21796,Q9H2D1,P12236,P45880,Q9BQT8,Q15041,Q6NUK1,Q9C0H2,Q9UBX3,Q9Y289,P07602,P51798,Q9Y277,P14174,P53985,Q02978,Q96NB2,Q9UHG3,Q08722,Q7L0J3,P0CG08,Q9H9B4,P28288,Q15758,Q96QD8,P12235,Q99808,Q9Y619,Q9NZJ7,P54105,Q9Y6M7,P30825,Q9H936,O43808,O43681,P22413,P30536,Q96S66,O75915,O60831,P08183,P51790 | Processes and pathways | GO Biological process | msigdb_gobp | 512,135,13,35,671,36,299,169,682,43,42,697,49,555,178,61,323,712,715,82,338,340,463,736,597,734,217,728,613,104,359,620,235,233,498,360,492,370,115,372,493,625,376,377 | 2146,492,360,844,625,845,493,829,2030,986,1661,49,376,913,463,2232,728,671,61,13,370,597,115,233,1843,2746,36,377,555,1295,323,620,878,1013,992,1066,712,338,1525,1461,169,2451,734,512,849,3353,682,2041,340,135,1747,715,217,372,613,299,43,761,35,1232,498,736,964,359,42,82,970,178,697,2284,104,3029,235 | -0.380580727609994,0.886046284757872,1.1611295689133987,0.3970534541929916,0.6952833352363743,0.3970534541929916,0.886046284757872,0.4116024166954531,-0.3144279325201492,0.27934845246757406,-0.1362731975345778,2.92158351686393,1.1354747011565787,0.3384952950336184,0.9394380703588899,-0.4139400483539833,0.5409506773670444,0.6256322496638714,2.688297793309567,3.665218562873702,1.1483160129394345,0.736682872551653,2.116827011264163,1.5691701875504565,-0.21658099121495536,-0.6879079811712451,3.173668490790479,1.1354747011565787,0.7914346484543726,0.052090308590681936,1.2374348642931197,0.7091154600079058,0.367847206626791,0.2644683279709449,0.27934845246757406,0.21960063359485635,0.5693132022609276,1.2121086826797591,-0.07281046412115222,-0.04133497065359173,1.8378675573382266,-0.5151766444670957,0.5409506773670444,0.8591685467310516,0.3970534541929916,-2.2704910421618587,0.6116028235314318,-0.3144279325201492,1.2121086826797591,1.9845509548727378,-0.1682642630641737,0.5693132022609276,1.6286223242764093,1.1483160129394345,0.7229152541390564,1.325234886963656,3.0255595862775544,0.512451026199518,3.191929224701824,0.09825091479754514,0.886046284757872,0.5409506773670444,0.3089962184714941,1.1739154920916346,3.034923654113158,2.445594751613174,0.3089962184714941,1.8149774576557305,0.5975399499868604,-0.43069141079578177,2.203413222336374,-0.8840205662190869,1.5691701875504565 | 3,381 |
Ion transmembrane transport | 72 | 165 | 4.825242 | 0.000001 | P56385,Q9UMX0,P05023,Q96PU5,Q8TB61,P05026,Q9UDW1,Q9BPX6,P21796,P20674,P46934,P00846,P06576,O43772,P27105,O75964,P00403,P16615,Q70HW3,Q9H2D1,P45880,P12236,Q9BQT8,Q15041,Q9UBX3,Q9C0H2,Q6P4Q7,P05067,Q9Y289,P51798,Q9Y277,P0DP25,P13073,Q02978,Q96NB2,P53985,Q9NWR8,P62258,P24539,P98194,Q9UHG3,Q6P4A7,Q9H0U3,Q07812,O75844,P0CG08,Q9H9B4,Q15758,P61421,P12235,P36542,Q9Y619,O95202,Q9Y6M7,Q8NE86,P30825,Q9HD20,O43808,P10606,Q9H936,Q9HC07,Q9Y4W6,P08183,O75915,Q13423,O95747,O60831,P56134,Q8IYU8,Q8NEW0,O14548,P51790 | Processes and pathways | GO Biological process | msigdb_gobp | 634,393,507,525,135,643,11,268,13,518,397,18,530,664,276,27,31,538,34,35,36,671,299,169,42,43,560,175,697,555,178,444,193,712,715,323,459,710,204,460,82,83,606,601,86,463,736,734,599,728,353,104,105,235,748,233,109,360,617,498,113,765,376,493,117,499,625,501,379,251,752,377 | 2146,911,752,1547,664,360,844,2850,625,1317,3004,1449,3031,1968,845,86,493,912,27,105,829,499,31,18,507,643,175,986,1661,530,2403,3034,2031,1042,376,913,949,463,444,617,1970,728,671,193,538,2002,2828,989,518,1594,3008,3281,13,204,1700,276,3202,2330,3115,1156,233,2610,1843,1519,353,1109,2374,2746,2035,36,397,2181,1111,2926,1346,377,555,1295,323,931,822,878,501,634,599,2187,710,899,2267,992,460,1066,993,712,2131,1067,601,3076,1299,2133,117,880,1461,1562,1462,169,1673,734,849,83,560,1919,34,2020,379,1309,748,251,135,1747,2841,2210,1377,715,525,3219,776,1206,904,268,299,1000,942,3343,43,606,2675,35,1232,2217,498,736,113,109,964,2733,1279,459,42,11,2116,82,1542,970,1104,1211,393,178,697,1692,2284,765,104,3029,235 | -0.380580727609994,0.3384952950336184,0.512451026199518,-0.088611824283511,0.6396283914658812,1.1611295689133987,0.3970534541929916,-0.7584596965728567,0.6952833352363743,0.036622396653028605,-0.8840205662190869,-0.04133497065359173,-0.9021810980072403,-0.281630105291349,0.3970534541929916,2.393772583906324,0.886046284757872,0.3384952950336184,3.3360620594700903,2.192658207659924,0.4116024166954531,0.8726226873579839,3.228285933657418,3.5287995182001897,0.8591685467310516,0.667521468415162,1.8149774576557305,0.27934845246757406,-0.1362731975345778,0.8321680621038776,-0.4981815098100403,-0.9021810980072403,-0.3144279325201492,0.23459461671822154,1.1354747011565787,0.3384952950336184,0.3089962184714941,0.9394380703588899,0.9923523595397633,0.7091154600079058,-0.281630105291349,0.5409506773670444,0.6256322496638714,1.7341630938766759,0.81862142870259,-0.2980060279588005,-0.7407414914126782,0.27934845246757406,0.8456837197085607,-0.10445590752084172,-0.8840205662190869,-1.3954664513686503,3.665218562873702,1.6874867509018345,-0.1522468865249289,1.3871636906481628,-1.1435826971822214,-0.46433895531968433,-0.9938445474628532,0.14405137258271195,1.5691701875504565,-0.6009028178865126,-0.21658099121495536,-0.07281046412115222,1.1866739046641297,0.17438776279080853,-0.4812357112409115,-0.6879079811712451,-0.3144279325201492,3.173668490790479,1.0838294064395717,-0.39723658082010016,0.17438776279080853,-0.8119401366404397,0.021113596394116325,1.1354747011565787,0.7914346484543726,0.052090308590681936,1.2374348642931197,0.3237642470959609,0.426115515627173,0.367847206626791,0.8726226873579839,0.6814187237709133,0.736682872551653,-0.39723658082010016,0.5693132022609276,0.35318955209666003,-0.43069141079578177,0.27934845246757406,0.9527110641842556,0.21960063359485635,0.27934845246757406,0.5693132022609276,-0.3639722106197193,0.21960063359485635,0.736682872551653,-0.9386732063062241,0.052090308590681936,-0.3639722106197193,2.1059150941587093,0.367847206626791,-0.04133497065359173,-0.088611824283511,-0.04133497065359173,1.8378675573382266,-0.1362731975345778,0.5409506773670444,0.3970534541929916,2.424919578143314,0.7914346484543726,-0.24901515263246263,3.191929224701824,-0.2980060279588005,1.1354747011565787,0.052090308590681936,0.5267180776783301,1.472793767169314,1.9845509548727378,-0.1682642630641737,-0.7407414914126782,-0.39723658082010016,0.005563685061401132,0.5693132022609276,0.8456837197085607,-1.1625745267284813,0.49814935110308256,0.11355746484162065,0.35318955209666003,1.4240134588486117,1.325234886963656,0.27934845246757406,0.3237642470959609,-1.9347483786498059,3.0255595862775544,0.736682872551653,-0.6355492145278823,3.191929224701824,0.09825091479754514,-0.39723658082010016,0.886046284757872,0.5409506773670444,2.138591310737635,2.1710900300592053,0.3089962184714941,-0.6704027435429782,0.0675175531380731,0.9659543529438528,3.034923654113158,3.7072278486138166,-0.34741075419628276,2.445594751613174,-0.07281046412115222,0.3089962184714941,0.18949740958903347,0.11355746484162065,1.109708313950368,1.8149774576557305,0.5975399499868604,-0.1362731975345778,-0.43069141079578177,0.512451026199518,2.203413222336374,-0.8840205662190869,1.5691701875504565 | 3,381 |
Inner mitochondrial membrane protein complex | 49 | 81 | 4.814744 | 0.000001 | O60830,P56385,Q99623,O14925,Q99595,P14406,Q9UDW1,Q96CU9,P20674,Q9BPX6,P56378,P00846,O75438,O43676,P06576,O75306,Q5XKP0,P09669,O75964,P00403,Q9NX63,P12236,Q9NX14,Q13505,O95168,Q9Y5J7,Q86Y39,Q6UXV4,O95298,P13073,Q9Y512,Q9NWR8,P14927,P24539,Q3ZCQ8,Q5HYI7,O14949,P36542,O75489,P03886,P22695,Q8NE86,Q96IX5,P15954,P10606,Q9Y4W6,P56134,Q8IYU8,O14548 | Localization | GO Cellular component | msigdb_gocc | 0,634,776,131,7,138,11,267,518,268,143,18,402,22,530,408,281,409,27,31,291,671,686,168,689,440,186,445,569,193,591,459,708,204,339,91,89,353,487,106,107,748,505,618,617,765,501,379,752 | 911,752,131,89,767,22,0,1449,408,1079,1061,402,487,912,27,689,1624,569,1899,1029,31,18,106,530,949,409,617,671,193,138,708,618,3037,518,820,107,204,1700,3294,1939,2610,1046,353,2666,1111,2926,3273,877,501,143,634,858,168,2243,1425,1158,339,861,91,281,445,186,379,748,267,505,7,776,268,1233,888,459,686,291,2734,11,1544,765,591,440,841 | 0.3384952950336184,0.512451026199518,1.995686459291915,2.3414986895471337,0.49814935110308256,3.4419514395165693,4.174427463103442,-0.04133497065359173,1.057836964111845,0.2045682986016007,0.21960063359485635,1.0708474410751416,0.8994394810907228,0.3384952950336184,3.3360620594700903,0.5975399499868604,-0.12034295190828731,0.7641221963157447,-0.24901515263246263,0.24955044852133723,3.228285933657418,3.5287995182001897,2.192658207659924,0.8321680621038776,0.3089962184714941,1.057836964111845,0.7091154600079058,0.6256322496638714,1.7341630938766759,1.9733946563787192,0.5693132022609276,0.7091154600079058,-0.9021810980072403,0.8456837197085607,0.426115515627173,2.1818838341505353,1.6874867509018345,-0.1522468865249289,-1.4752260653101277,-0.2652999006953658,-0.6009028178865126,0.23459461671822154,1.1866739046641297,-0.6355492145278823,0.17438776279080853,-0.8119401366404397,-1.3559951108874018,0.367847206626791,0.8726226873579839,1.8947115570425241,0.6814187237709133,0.38246844551024856,1.8378675573382266,-0.4139400483539833,-0.0256603710645763,0.14405137258271195,1.2121086826797591,0.38246844551024856,2.3414986895471337,1.3748294740816678,0.9923523595397633,1.7689320262511543,1.1354747011565787,0.5267180776783301,1.4240134588486117,0.8726226873579839,3.839736848219882,0.49814935110308256,1.4240134588486117,0.09825091479754514,0.367847206626791,0.9659543529438528,0.6116028235314318,1.3500839456990343,-0.6704027435429782,3.7072278486138166,-0.07281046412115222,0.512451026199518,0.7504184690468082,1.0055073471610068,0.4116024166954531 | 3,381 |
Membrane protein complex | 146 | 307 | 4.811731 | 0.000001 | O60830,Q9NS69,Q13277,P05023,Q99595,Q9UDW1,P21796,P20674,P00846,O43676,P06576,O75964,Q8N4H5,P00403,P45880,P04439,Q9C0H2,P51798,P51809,O43752,Q9Y487,O95298,Q8N511,Q9Y512,P67812,Q5J8M3,Q8TCT9,Q93050,Q07812,Q9H0U3,Q5HYI7,O14949,O94901,P61421,Q9P2W9,Q9Y5M8,P03886,P22695,P15954,P10606,O95249,P56385,Q8TCJ2,O14925,P14406,P05026,O96008,P56378,Q5VZ89,P12236,Q9NX14,Q13505,Q15041,Q9BUN8,Q9Y277,Q13438,O60749,O95168,Q86Y39,P13073,P14927,P63218,P24539,P61009,O43464,Q8N2K0,P12235,Q9NR28,Q8NE86,O60499,Q9Y4W6,O43292,Q9P253,Q15388,O14548,Q9P0I2,Q9UBV2,Q9GZP9,Q99623,O43674,Q96CU9,Q9BPX6,Q86Y82,O15269,Q9UGP8,Q5XKP0,Q07666,Q9NX63,P25054,Q9UNH7,Q9NPA0,P21912,P54709,P09496,Q9UHA4,Q9Y6M9,O75340,Q6IAA8,Q4KMQ2,Q3ZCQ8,Q9Y5X3,Q9NR31,Q9Y6B6,Q8IWA4,P46977,P36542,Q03518,P49755,Q92542,P56556,Q53H12,Q9NVH1,Q96S66,P51970,Q8IYU8,Q14254,Q9H9H4,Q9BRG1,Q99996,P62942,O15498,Q13190,P01889,P00533,Q92572,O75438,O75306,P09669,P08195,O75947,O95721,O43633,Q9Y5J7,Q6UXV4,P0DP25,P51571,Q9NWR8,P10321,Q53GQ0,O15400,O75489,P04843,P56134,Q12981,Q8NDZ4,Q96IX5 | Localization | GO Cellular component | msigdb_gocc | 0,2,511,507,7,11,13,518,18,22,530,27,29,31,36,546,43,555,566,60,63,569,67,591,74,584,77,79,601,606,91,89,595,599,97,103,106,107,618,617,114,634,647,131,138,643,642,143,655,671,686,168,169,177,178,692,184,689,186,193,708,711,204,720,218,222,728,226,748,237,765,243,763,250,752,778,262,261,776,767,267,268,784,271,803,281,794,291,788,818,303,820,822,309,838,841,828,850,849,339,341,351,873,348,342,353,859,355,356,858,861,888,372,877,379,881,908,391,904,899,386,388,396,894,922,402,408,409,913,912,415,420,440,445,444,450,459,454,480,476,487,500,501,502,504,505 | 2557,2945,2146,2764,911,1041,752,2738,2678,3189,131,89,2765,271,1656,476,386,243,218,420,767,22,2659,60,1316,237,1129,184,0,1449,408,828,1079,1094,1061,1409,402,487,912,1194,27,1761,1238,595,2897,1586,689,1624,114,569,1899,1588,1763,415,3191,1029,642,31,894,18,396,1803,106,546,500,1289,2632,507,643,986,1661,530,2403,2031,913,949,1412,1195,309,409,444,454,617,2803,2328,728,671,193,138,2404,708,618,2002,1901,3037,518,1594,3008,13,820,2372,107,204,788,1700,1902,3294,2949,1973,3115,1939,2610,2034,952,1046,1595,353,1109,2374,2666,1807,2746,2413,36,2181,342,1111,2926,1047,2415,1220,355,3273,450,555,566,877,3119,2093,1597,2338,931,822,1704,2185,2156,501,143,634,858,2445,1049,720,599,2187,3336,1264,899,1416,2159,711,74,1225,859,1459,1324,794,601,1602,3076,2133,502,2504,388,511,692,2308,168,2342,1069,881,1816,1980,934,935,169,975,1673,250,1528,1082,1036,2243,1425,1158,339,849,480,861,1269,91,584,1739,655,281,850,445,186,784,348,379,222,29,67,1498,1888,504,748,2454,647,77,1747,3056,1020,356,922,1184,1784,79,1230,1356,1959,267,2047,2974,505,1248,1534,372,3125,7,776,1187,1023,904,268,391,177,3380,43,261,606,2955,908,1233,1830,303,226,351,2,2733,888,1538,459,686,291,1793,778,2734,763,97,1616,2435,944,2253,968,262,1687,11,803,984,838,1542,2398,2492,1283,818,1284,2055,1619,1544,178,1252,1508,63,765,591,440,1153,103,341,3138,1695,3029,873,3201,841 | 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er | 40 | 91 | 4.784985 | 0.000002 | Q9H6H4,Q00765,Q15125,O15173,Q13190,P48651,O15269,Q16850,Q86Y07,Q969Q5,P51572,P61019,O00264,Q14739,Q15041,Q9NPA0,Q86UL3,O95674,Q8NHH9,Q9Y487,Q9BVG9,Q15363,Q9NQC3,Q9NR31,Q15392,Q96A33,P46977,Q9P2W9,O95470,P49755,Q07065,Q9Y5M8,Q96N66,O60499,O75845,O75915,P04843,Q12981,O96005,Q9Y3E0 | Localization | OpenCell Localization | opencell_localization | 385,509,9,10,388,520,271,145,404,279,411,418,38,424,169,303,429,435,438,63,335,81,213,351,346,221,342,97,98,355,229,103,364,237,361,493,500,502,119,517 | 38,766,10,271,1656,237,828,1094,361,493,1839,98,435,119,1935,1255,500,1289,2368,1591,988,2948,856,1807,342,2183,520,355,678,1491,411,2185,2445,2748,418,990,3336,2688,509,1669,229,502,388,424,935,169,9,81,346,1952,1605,145,584,541,2041,3146,429,404,1498,1639,835,438,684,647,3056,1985,2486,279,2431,221,2974,364,1856,1857,335,1278,1474,385,1435,303,213,351,738,778,1867,97,1211,517,63,103,873 | 3.081527209308513,0.49814935110308256,3.7239504780013903,1.3994723547109182,-0.1362731975345778,1.5452220568165775,0.4116024166954531,0.18949740958903347,1.1611295689133987,0.886046284757872,-0.21658099121495536,2.235562824872222,1.0055073471610068,2.0620672301078167,-0.2652999006953658,0.0675175531380731,0.8726226873579839,0.052090308590681936,-0.4812357112409115,-0.10445590752084172,0.27934845246757406,-0.8298767033583657,0.38246844551024856,-0.20043106596845775,1.1994049280050039,-0.39723658082010016,0.8456837197085607,1.1866739046641297,0.6116028235314318,-0.05705159094963218,1.057836964111845,-0.39723658082010016,-0.5151766444670957,-0.6879079811712451,1.0447978465606236,0.27934845246757406,-1.8057507188165074,-0.6529499285349974,0.8591685467310516,-0.1362731975345778,1.5811082112453032,0.8726226873579839,1.109708313950368,1.031729958547143,0.3237642470959609,1.8378675573382266,3.790384154242022,2.445594751613174,1.1994049280050039,-0.2652999006953658,-0.10445590752084172,1.8833859877895984,0.7504184690468082,0.81862142870259,-0.3144279325201492,-1.030918643087974,1.0186331693037094,1.0708474410751416,-0.05705159094963218,-0.12034295190828731,0.4116024166954531,1.0055073471610068,0.6116028235314318,0.667521468415162,-0.9203985222019436,-0.281630105291349,-0.5322214113175786,1.3871636906481628,-0.4981815098100403,1.6167792983058513,-0.8478687275943366,1.1611295689133987,-0.21658099121495536,-0.21658099121495536,1.2247852884525057,0.0675175531380731,-0.04133497065359173,1.1226055097209044,-0.0256603710645763,1.3127712547525017,1.640441843029371,1.1994049280050039,0.5409506773670444,0.49814935110308256,-0.21658099121495536,2.2781622213637456,0.11355746484162065,0.8591685467310516,2.6783785011395778,2.203413222336374,0.38246844551024856 | 3,381 |
Intrinsic component of endoplasmic reticulum membrane | 28 | 56 | 4.754767 | 0.000002 | Q9GZP9,P49069,Q8TB61,Q15125,P01889,Q86XL3,P51572,P04439,Q15041,Q9P035,Q969X5,Q9Y282,Q99442,Q9NPA0,Q9BUN8,Q15629,O75298,P10321,Q8TCT9,Q9Y4P3,Q9NQC3,O75844,Q96A33,Q8TCT8,O95470,Q86YN1,O43292,Q12981 | Localization | GO Cellular component | msigdb_gocc | 261,6,135,9,396,154,411,546,169,300,431,46,432,303,177,65,199,454,77,469,213,86,221,223,98,100,243,502 | 1253,766,1168,243,199,86,716,98,396,546,454,1902,856,1973,6,411,644,2187,859,1459,502,2134,935,169,9,65,1142,584,997,154,100,1498,135,223,77,1184,1230,431,221,1534,432,1857,177,261,1335,303,213,1123,300,778,2395,1477,1211,46,469,1695 | 0.0675175531380731,0.49814935110308256,0.128824213397895,1.5091181530837137,1.7108706217957421,2.393772583906324,0.5551489958059633,2.235562824872222,1.0838294064395717,0.8050436732526357,0.9659543529438528,-0.24901515263246263,0.38246844551024856,-0.281630105291349,3.8479234632840806,1.057836964111845,0.667521468415162,-0.39723658082010016,0.38246844551024856,-0.04133497065359173,0.8726226873579839,-0.3639722106197193,0.3237642470959609,1.8378675573382266,3.790384154242022,2.658490686895177,0.15923915280621745,0.7504184690468082,0.27934845246757406,1.8720388877331144,2.235562824872222,-0.05705159094963218,1.9845509548727378,1.6049126688329458,2.527590393054582,0.128824213397895,0.09825091479754514,1.0186331693037094,1.6167792983058513,-0.07281046412115222,1.0186331693037094,-0.21658099121495536,1.8149774576557305,1.4484536466130733,0.036622396653028605,1.3127712547525017,1.640441843029371,0.17438776279080853,1.325234886963656,0.49814935110308256,-0.4812357112409115,-0.04133497065359173,0.11355746484162065,2.9690677810146133,0.9394380703588899,-0.1362731975345778 | 3,381 |
Vacuole | 84 | 236 | 4.723592 | 0.000002 | P00813,Q13277,P50897,Q14108,Q13510,P53634,O15260,Q99538,O75629,Q8IV08,P07602,P51798,P11279,O95772,Q14849,P51809,Q8IY95,Q9UMR5,Q9BXS4,P54802,Q9Y487,O95298,Q5BJF2,Q8N511,P04062,Q8NHP8,P50995,Q93050,Q9UHG3,Q9H0U3,O75503,O14773,Q8WTV0,Q01085,P13473,P61421,Q9HC07,P06865,P42785,P10619,P07858,P42892,P15586,Q9BTY2,Q9NQX7,P17900,Q9H2V7,O60749,P38435,Q9UIQ6,Q8TCT8,O00584,Q07065,Q9H0B6,P04066,Q05639,P06280,Q969Q5,P27105,Q9NX40,O15118,P11117,P61916,P09496,Q9UM22,Q15165,Q92542,Q9NZJ7,P10253,P22413,Q8IW92,P51790,Q9UMX0,P16278,P61019,O95721,O43633,Q9Y6I9,Q86YV9,Q16625,P08236,O15400,Q13501,O43681 | Localization | GO Cellular component | msigdb_gocc | 1,511,3,5,26,548,39,562,45,47,49,555,554,54,55,566,568,58,577,62,63,569,66,67,71,72,580,79,82,606,87,88,92,600,596,599,113,116,120,128,137,140,144,147,149,150,167,184,200,214,223,227,229,232,238,249,255,279,276,285,286,301,306,309,321,345,356,359,368,370,378,377,393,410,418,415,420,441,466,465,470,476,489,492 | 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| 3,381 |
Membrane organization | 84 | 248 | 4.653086 | 0.000003 | Q13277,P50897,Q9NS69,Q00765,P49069,Q16739,Q6NUK4,P16615,P45880,P51809,Q14849,O43752,Q15629,Q9Y5L4,Q9Y512,Q5J8M3,Q14696,Q15363,Q07812,O75844,Q5HYI7,O94901,Q9P2W9,O95202,Q8IXJ6,O95249,P30536,O14737,P57088,P05026,O15027,Q86XL3,P52789,Q13505,Q15041,Q9Y5J9,O43760,Q9NQC3,O60220,Q96A33,Q9BZG1,Q8N8Q8,O60499,Q5XKP0,Q9H3K2,Q9NX63,O15118,Q9NPA0,P61916,P50402,Q9BVK6,Q8N3R9,P31751,P10909,Q3ZCQ8,Q9NR31,Q8IWA4,Q15392,P49755,Q9NZJ7,Q8N1F7,P08183,P51790,O15258,Q9H6H4,O15498,Q13190,Q9H4A5,P31749,O95721,O43633,Q9H4A6,Q8NHH9,Q9Y5J7,Q6UXV4,P0DP25,O60313,P17152,P98194,Q9UQB8,P46379,O15400,O43681,Q12981 | Processes and pathways | GO Biological process | msigdb_gobp | 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| 3,381 |
Inorganic molecular entity transmembrane transporter activity | 43 | 77 | 4.652025 | 0.000003 | P56385,P05023,P05026,Q9UDW1,P21796,P20674,P00846,P06576,O75964,P00403,P16615,P45880,Q9UBX3,Q9C0H2,Q6P4Q7,Q9Y289,P51798,Q9Y277,Q9Y487,P13073,Q02978,Q9NWR8,P24539,P98194,Q93050,Q9H0U3,P0CG08,Q96QD8,P61421,P12235,P36542,O95202,Q9Y6M7,Q8NE86,Q9HD20,Q9H936,P10606,Q9HC07,O43681,Q96S66,Q13423,P56134,P51790 | Functions | GO Molecular function | msigdb_gomf | 634,507,643,11,13,518,18,530,27,31,538,36,42,43,560,697,555,178,63,193,712,459,204,460,79,606,463,217,599,728,353,105,235,748,109,498,617,113,492,372,117,501,377 | 2146,752,492,912,27,105,31,18,507,643,986,530,2403,1042,913,949,463,617,728,193,538,989,518,1594,3008,13,204,1700,2610,1843,353,1109,2374,36,1111,2926,377,555,878,501,634,599,2187,460,1066,993,712,117,849,3353,560,748,1747,2841,79,2210,217,372,2212,43,606,1232,498,113,109,1279,459,42,11,1542,1211,178,697,63,1153,3029,235 | -0.380580727609994,0.512451026199518,0.886046284757872,0.3384952950336184,3.3360620594700903,2.192658207659924,3.228285933657418,3.5287995182001897,0.8591685467310516,0.667521468415162,0.27934845246757406,0.8321680621038776,-0.4981815098100403,0.23459461671822154,0.3384952950336184,0.3089962184714941,0.9394380703588899,0.7091154600079058,0.5409506773670444,1.7341630938766759,0.81862142870259,0.27934845246757406,0.8456837197085607,-0.10445590752084172,-0.8840205662190869,3.665218562873702,1.6874867509018345,-0.1522468865249289,-0.6009028178865126,-0.21658099121495536,1.1866739046641297,0.17438776279080853,-0.4812357112409115,3.173668490790479,0.17438776279080853,-0.8119401366404397,1.1354747011565787,0.7914346484543726,0.367847206626791,0.8726226873579839,0.6814187237709133,0.736682872551653,-0.39723658082010016,0.9527110641842556,0.21960063359485635,0.27934845246757406,0.5693132022609276,2.1059150941587093,0.3970534541929916,-2.2704910421618587,0.7914346484543726,0.5267180776783301,-0.1682642630641737,-0.7407414914126782,2.4969731427236144,-0.39723658082010016,1.6286223242764093,1.1483160129394345,-0.39723658082010016,3.0255595862775544,0.736682872551653,0.09825091479754514,0.886046284757872,2.138591310737635,2.1710900300592053,0.0675175531380731,0.9659543529438528,3.034923654113158,3.7072278486138166,-0.07281046412115222,0.11355746484162065,1.8149774576557305,0.5975399499868604,2.6783785011395778,0.15923915280621745,-0.8840205662190869,1.5691701875504565 | 3,381 |
Mental deterioration | 34 | 98 | 4.635138 | 0.000004 | P50897,Q14108,P00846,O75306,Q5XKP0,P17900,Q13510,P35637,P16278,P00403,O15118,P22626,P27544,P05067,P07602,P61916,Q9BQE5,Q9Y287,P54802,Q9Y487,O60313,P04062,O75503,O43464,O60220,Q9NQZ5,O95470,P31483,Q9NZJ7,Q13501,P03886,Q10713,P06865,Q05639 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 3,5,18,408,281,150,26,151,410,31,286,416,164,175,49,306,53,189,62,63,443,71,87,218,219,483,98,477,359,489,106,242,116,249 | 1727,286,218,492,1028,219,443,2364,2713,408,87,716,1625,98,642,31,18,106,71,2059,175,116,49,677,1550,855,3236,1318,410,2947,150,1239,755,820,781,416,2962,164,1939,477,151,1109,2374,2477,2035,953,3168,3,2719,2879,62,1943,2185,858,306,1705,1225,3346,2380,249,1067,1137,242,1908,489,26,5,1373,2884,1426,281,3160,1202,2426,657,900,1888,1273,2839,2888,1248,1249,1400,3219,3250,53,1431,3110,590,483,2252,359,1003,2707,909,1619,189,63 | -0.1682642630641737,1.3500839456990343,1.6167792983058513,0.886046284757872,0.24955044852133723,1.6167792983058513,0.9923523595397633,-0.4812357112409115,-0.6704027435429782,1.057836964111845,2.38335420134735,0.5551489958059633,-0.12034295190828731,2.235562824872222,0.667521468415162,3.228285933657418,3.5287995182001897,2.192658207659924,2.5984293534561167,-0.33089608510881563,1.8149774576557305,2.1059150941587093,2.92158351686393,0.6116028235314318,-0.088611824283511,0.38246844551024856,-1.2391699285723725,0.036622396653028605,1.057836964111845,-0.8298767033583657,1.8720388877331144,0.08290434942458566,0.512451026199518,0.426115515627173,0.4838128792612018,1.0447978465606236,-0.8478687275943366,1.8492797575498616,-0.2652999006953658,0.912802417517626,1.8720388877331144,0.17438776279080853,-0.4812357112409115,-0.5322214113175786,-0.3144279325201492,0.3089962184714941,-1.0682309118829818,3.9694178630460812,-0.6704027435429782,-0.7762319784315349,2.688297793309567,-0.2652999006953658,-0.39723658082010016,0.38246844551024856,1.3002814037400503,-0.1522468865249289,0.09825091479754514,-1.9565316711758953,-0.4812357112409115,1.4970346589149368,0.21960063359485635,0.15923915280621745,1.521177149662278,-0.24901515263246263,0.8994394810907228,3.3538394683675534,3.8560990647949103,0.005563685061401132,-0.7762319784315349,-0.0256603710645763,1.3748294740816678,-1.0495448094461048,0.11355746484162065,-0.4981815098100403,0.6535914108187438,0.35318955209666003,-0.2327756018219659,0.0675175531380731,-0.7407414914126782,-0.7762319784315349,0.08290434942458566,0.08290434942458566,-0.01002756193935577,-1.1625745267284813,-1.2778505036844956,2.844821658588297,-0.0256603710645763,-0.9753958423265335,0.7504184690468082,0.912802417517626,-0.4139400483539833,1.1739154920916346,0.27934845246757406,-0.6529499285349974,0.35318955209666003,-0.10445590752084172,1.7689320262511543,2.6783785011395778 | 3,381 |
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