term stringlengths 2 121 | overlap int64 6 281 | setsize int64 7 499 | score float64 1.96 10.6 | pval float64 0 0.05 | edge stringlengths 41 1.97k | type stringclasses 5 values | subtype stringclasses 24 values | subtype_key stringclasses 24 values | edge_idxs stringlengths 11 1.17k | ann_idxs stringlengths 19 2.31k | ann_vals stringlengths 124 9.94k | sig_size int64 2.2k 3.73k |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
K Homology domain [IPR004087] | 13 | 23 | 2.148631 | 0.031664 | Q92667,P61978,Q9NRX1,Q96I24,Q15365,Q96PU8,Q9Y2W6,Q07666,Q92945,Q15366,Q96AE4,P51114,P51116 | Sequence | InterPro Domain | interpro_domain | 128,661,786,366,381,690,108,491,179,856,808,221,192 | 2351,1308,221,192,661,2331,850,491,2230,381,856,1606,1535,128,179,808,366,690,786,1995,2045,108,1865 | -0.5955577777283037,0.04733436242856619,1.364397823611464,1.4452649342552104,0.5725751879550428,-0.5719634057535422,0.3998733474246863,0.7853489674913086,-0.501480515213417,0.9740581370180955,0.3998733474246863,-0.13277690412101875,-0.08749607248094354,1.764486885826947,1.5056302422299026,0.443262882592413,1.0156498223536288,0.5511109868815428,0.4649035470490806,-0.36182891654219795,-0.38498514034941356,1.9216692731632823,-0.2696675832309689 | 3,053 |
Demethylation | 7 | 16 | 2.137687 | 0.032542 | Q9Y570,Q9C0B1,Q8NB78,Q9NRW3,Q01804,Q9Y2K7,Q16850 | Processes and pathways | GO Biological process | msigdb_gobp | 421,497,560,273,295,376,153 | 2125,822,1593,295,1602,153,1050,728,559,560,963,1848,497,273,376,421 | -0.45473795795566646,0.42158622887203256,-0.13277690412101875,1.1396995480631378,-0.13277690412101875,1.6057075498374067,0.24684817531299486,0.5080778484189623,0.7006411186565148,0.7006411186565148,0.31265467698410715,-0.2696675832309689,0.7853489674913086,1.2013248973084056,0.9948692957811976,0.9114390602469016 | 3,053 |
Anaphase promoting complex | 6 | 9 | 2.136773 | 0.032616 | Q12834,O60566,Q16763,Q9UJX3,P30260,Q96DE5 | Localization | GO Cellular component | msigdb_gocc | 359,550,437,188,658,61 | 550,658,359,437,61,965,693,188,1619 | 0.7006411186565148,0.5725751879550428,1.0156498223536288,0.8695365017538665,2.3461771153462627,0.31265467698410715,0.5511109868815428,1.4654136081925186,-0.13277690412101875 | 3,053 |
Rna stabilization | 8 | 25 | 2.131668 | 0.033034 | Q14103,O95453,P35637,Q13148,P98175,O60506,Q92804,Q9H814 | Processes and pathways | GO Biological process | msigdb_gobp | 451,469,137,517,358,212,154,321 | 212,1971,1146,469,2455,1313,137,2068,358,1560,1600,851,517,829,518,451,1437,1021,1327,154,2344,1855,321,1995,1658 | 1.3846557563241517,-0.36182891654219795,0.15856954701810255,0.8064441353972578,-0.6666471270313368,0.04733436242856619,1.724944276613307,-0.4081884661759546,1.0156498223536288,-0.11011503607208795,-0.13277690412101875,0.3998733474246863,0.7430608810149629,0.42158622887203256,0.7430608810149629,0.8485377081326498,-0.019893426729216315,0.26882156691646053,0.04733436242856619,1.6057075498374067,-0.5719634057535422,-0.2696675832309689,1.0984691394737887,-0.36182891654219795,-0.1554820011028002 | 3,053 |
Ubiquitin like protein transferase activity | 26 | 59 | 2.128085 | 0.03333 | Q14139,O95628,P19474,Q9ULT8,Q9C0C9,Q9NR09,Q9UJX2,Q99496,Q16763,Q14527,Q6W2J9,Q9UBS8,Q9P253,Q5VTB9,O75150,Q96PU5,Q5W0B1,O95155,Q96J02,Q15386,P22681,O95376,Q96MF7,P38398,O95714,Q7Z7E8 | Functions | GO Molecular function | msigdb_gomf | 775,15,269,675,413,814,693,705,437,569,65,66,200,702,456,80,216,332,752,492,234,739,386,624,501,779 | 2959,456,1708,1010,2380,1624,332,739,15,501,269,234,624,1153,2288,2693,2329,1915,881,1721,1602,1491,775,1167,569,2073,492,437,1725,913,702,216,65,2594,1925,779,2338,1730,1811,941,752,386,80,833,705,413,814,1001,2449,200,66,693,675,2474,1302,2086,2244,1507,2411 | -1.5863829117981387,0.8275069838030819,-0.20102320141396507,0.26882156691646053,-0.6192028971632252,-0.1554820011028002,1.0571196890420318,0.48650845797534237,3.5960411197517193,0.7642212825740413,1.2013248973084056,1.3034573165650833,0.6153999674831028,0.15856954701810255,-0.5484193521639549,-0.90706803754792,-0.5719634057535422,-0.3156562729795899,0.3781239970118069,-0.20102320141396507,-0.13277690412101875,-0.06491969310546976,0.4649035470490806,0.15856954701810255,0.6793813477027839,-0.4081884661759546,0.7853489674913086,0.8695365017538665,-0.20102320141396507,0.3563379335731602,0.5296119487856337,1.3846557563241517,2.2889304994100175,-0.7861770917100085,-0.3156562729795899,0.4649035470490806,-0.5719634057535422,-0.20102320141396507,-0.24674132056841452,0.3345149101794884,0.48650845797534237,0.9740581370180955,2.154582729798314,0.42158622887203256,0.5296119487856337,0.9323432018484419,0.443262882592413,0.2907569811734416,-0.6428991995691181,1.4452649342552104,2.2889304994100175,0.5511109868815428,0.5725751879550428,-0.6666471270313368,0.06966173419709126,-0.4081884661759546,-0.501480515213417,-0.06491969310546976,-0.6192028971632252 | 3,053 |
Autophagy | 11 | 49 | 2.122946 | 0.033758 | Q9Y4P8,Q9NS69,Q8N4H5,Q8IWA4,Q13501,P21796,P49815,O96008,Q9Y4P1,P04350,Q9H9H4 | Processes and pathways | Reactome Pathways | msigdb_reactome | 98,3,237,341,47,20,335,369,124,275,261 | 2949,1707,1340,1746,1873,369,275,1943,1975,1312,2180,2544,20,600,335,1912,1633,2549,2902,1915,953,1374,934,1636,47,1604,2261,2979,957,2438,341,237,2405,996,1645,2878,649,756,1539,261,811,3,1001,1862,1578,2165,124,98,443 | -1.534366639104802,-0.20102320141396507,0.02496624326774895,-0.22385997559133067,-0.29263911521091057,0.9948692957811976,1.1808122620382033,-0.3387194179434577,-0.36182891654219795,0.04733436242856619,-0.47808490468523474,-0.7382051822514453,3.381602740630259,0.6367609840083165,1.0571196890420318,-0.3156562729795899,-0.1554820011028002,-0.7382051822514453,-1.3291786390974751,-0.3156562729795899,0.31265467698410715,0.0025570802874198603,0.3345149101794884,-0.1554820011028002,2.573242040306225,-0.13277690412101875,-0.524925194185422,-1.8242826876496403,0.31265467698410715,-0.6428991995691181,1.0571196890420318,1.3034573165650833,-0.6192028971632252,0.2907569811734416,-0.1554820011028002,-1.2533654408572235,0.5940047747374697,0.48650845797534237,-0.08749607248094354,1.2422635378120828,0.443262882592413,5.592463933325356,0.2907569811734416,-0.2696675832309689,-0.11011503607208795,-0.45473795795566646,1.803929707635828,1.9607226861740548,0.8695365017538665 | 3,053 |
Translocation | 9 | 45 | 2.10601 | 0.035203 | Q9NS69,P37198,Q9BTX1,P52948,Q99595,Q7Z3B4,O60830,Q9NRG9,Q15629 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 3,324,43,235,51,217,24,352,63 | 2003,513,2970,654,24,1144,901,2607,771,324,2816,392,1153,235,2520,2831,2105,2330,1673,955,63,1803,958,217,1053,1927,645,939,1689,1571,1174,1055,1849,1298,631,51,43,1401,1500,352,3,2558,2348,1700,2908 | -0.38498514034941356,0.7430608810149629,-1.6913249130708796,0.5725751879550428,3.2734630387792905,0.15856954701810255,0.3563379335731602,-0.8102444399713625,0.4649035470490806,1.077809379742811,-1.1034851164802537,0.9532161662596518,0.15856954701810255,1.3034573165650833,-0.7142996591987354,-1.1283078220968537,-0.4314392761759522,-0.5719634057535422,-0.17823065580578884,0.31265467698410715,2.3271166761662077,-0.24674132056841452,0.31265467698410715,1.3846557563241517,0.24684817531299486,-0.3156562729795899,0.5940047747374697,0.3345149101794884,-0.17823065580578884,-0.11011503607208795,0.15856954701810255,0.24684817531299486,-0.2696675832309689,0.06966173419709126,0.6153999674831028,2.5167589592971633,2.6482659504229598,0.0025570802874198603,-0.06491969310546976,1.036399894714161,5.592463933325356,-0.7382051822514453,-0.5719634057535422,-0.17823065580578884,-1.3291786390974751 | 3,053 |
Sterol metabolic process | 8 | 38 | 2.076563 | 0.037842 | Q14534,Q8WTV0,Q9BQE5,Q15392,P48449,Q14849,Q06520,Q16850 | Processes and pathways | GO Biological process | msigdb_gobp | 160,34,67,4,36,70,14,153 | 2559,2479,2562,2988,1311,2009,2784,502,1945,822,2666,720,294,1346,3045,2789,36,931,2854,626,2331,2292,14,2298,160,193,70,1382,2194,4,2760,724,153,34,67,1210,837,1900 | -0.7621641673616228,-0.6904471283524107,-0.7621641673616228,-1.986607236530285,0.04733436242856619,-0.38498514034941356,-1.0540235788334475,0.7642212825740413,-0.3387194179434577,0.42158622887203256,-0.8827779909790987,0.5080778484189623,1.1396995480631378,0.02496624326774895,-3.808381988853185,-1.0540235788334475,2.722967138304573,0.3345149101794884,-1.1781401567013674,0.6153999674831028,-0.5719634057535422,-0.5484193521639549,3.666989822854212,-0.5484193521639549,1.5657555247047086,1.4452649342552104,2.2122941644519587,0.0025570802874198603,-0.47808490468523474,5.036022265834179,-1.0048032596858985,0.5080778484189623,1.6057075498374067,2.760198415947888,2.2506565969990633,0.13640227399311802,0.42158622887203256,-0.29263911521091057 | 3,053 |
Selective autophagy | 7 | 31 | 2.074412 | 0.038041 | Q9NS69,Q8N4H5,Q8IWA4,Q13501,P21796,O96008,P04350 | Processes and pathways | Reactome Pathways | msigdb_reactome | 3,237,341,47,20,369,275 | 2949,1340,1746,369,275,1943,1312,2180,2544,20,1912,1633,2549,1915,953,1374,934,1636,47,1604,2261,2979,957,341,237,1645,2878,756,1539,3,443 | -1.534366639104802,0.02496624326774895,-0.22385997559133067,0.9948692957811976,1.1808122620382033,-0.3387194179434577,0.04733436242856619,-0.47808490468523474,-0.7382051822514453,3.381602740630259,-0.3156562729795899,-0.1554820011028002,-0.7382051822514453,-0.3156562729795899,0.31265467698410715,0.0025570802874198603,0.3345149101794884,-0.1554820011028002,2.573242040306225,-0.13277690412101875,-0.524925194185422,-1.8242826876496403,0.31265467698410715,1.0571196890420318,1.3034573165650833,-0.1554820011028002,-1.2533654408572235,0.48650845797534237,-0.08749607248094354,5.592463933325356,0.8695365017538665 | 3,053 |
S-adenosyl-L-methionine-dependent methyltransferase [IPR029063] | 14 | 31 | 2.074321 | 0.038049 | P21964,Q08J23,O43148,Q7L592,Q6P2P2,Q9UET6,Q9BV86,P22061,Q6FI81,Q96P11,Q8N6R0,Q86X55,O60678,P52788 | Sequence | InterPro Superfamily | interpro_homologous_superfamily | 225,851,636,364,382,106,48,457,373,613,610,350,872,848 | 869,636,1248,872,1784,225,457,2183,1631,2817,983,848,851,373,382,1051,364,2111,1230,350,1393,1569,610,613,1057,1208,48,1405,1651,106,2210 | 0.3781239970118069,0.5940047747374697,0.09194865127890278,0.3781239970118069,-0.24674132056841452,1.3441122067215945,0.8275069838030819,-0.47808490468523474,-0.1554820011028002,-1.1034851164802537,0.2907569811734416,0.3998733474246863,0.3998733474246863,0.9948692957811976,0.9740581370180955,0.24684817531299486,1.0156498223536288,-0.4314392761759522,0.11419540272429664,1.036399894714161,0.0025570802874198603,-0.11011503607208795,0.6367609840083165,0.6367609840083165,0.24684817531299486,0.13640227399311802,2.554434984977978,0.0025570802874198603,-0.1554820011028002,1.9216692731632823,-0.47808490468523474 | 3,053 |
Protein polyubiquitination | 22 | 45 | 2.0709 | 0.038368 | P19474,Q9ULT8,Q9C0C9,P30260,Q9UJX2,Q16763,Q9UJX3,Q9UBS8,O75150,Q96PU5,P63208,O95155,Q9UIQ6,Q96J02,P55786,Q15386,P22681,P52888,O00571,O95376,P38398,Q7Z7E8 | Processes and pathways | GO Biological process | msigdb_gobp | 269,675,413,658,693,437,188,66,456,80,337,332,94,752,99,492,234,742,737,739,624,779 | 737,456,1624,332,739,269,234,1788,658,1878,624,742,99,2329,1915,337,881,1603,1491,2944,2071,775,2073,492,437,1925,779,2338,2982,752,80,2117,413,965,2449,66,94,693,188,1619,675,2474,1302,1213,2411 | 0.48650845797534237,0.8275069838030819,-0.1554820011028002,1.0571196890420318,0.48650845797534237,1.2013248973084056,1.3034573165650833,-0.24674132056841452,0.5725751879550428,-0.29263911521091057,0.6153999674831028,0.48650845797534237,1.9412079120317214,-0.5719634057535422,-0.3156562729795899,1.0571196890420318,0.3781239970118069,-0.13277690412101875,-0.06491969310546976,-1.508469190198362,-0.4081884661759546,0.4649035470490806,-0.4081884661759546,0.7853489674913086,0.8695365017538665,-0.3156562729795899,0.4649035470490806,-0.5719634057535422,-1.8511212916446877,0.48650845797534237,2.154582729798314,-0.4314392761759522,0.9323432018484419,0.31265467698410715,-0.6428991995691181,2.2889304994100175,1.9802137107360143,0.5511109868815428,1.4654136081925186,-0.13277690412101875,0.5725751879550428,-0.6666471270313368,0.06966173419709126,0.13640227399311802,-0.6192028971632252 | 3,053 |
Negative regulation of mrna catabolic process | 7 | 22 | 2.041451 | 0.041206 | Q14103,P35637,Q13148,Q99729,P98175,O60506,Q92804 | Processes and pathways | GO Biological process | msigdb_gobp | 451,137,517,430,358,212,154 | 212,1146,2455,1313,137,2068,358,1560,850,1600,517,829,518,451,1437,1021,1327,154,430,2344,1995,1658 | 1.3846557563241517,0.15856954701810255,-0.6666471270313368,0.04733436242856619,1.724944276613307,-0.4081884661759546,1.0156498223536288,-0.11011503607208795,0.3998733474246863,-0.13277690412101875,0.7430608810149629,0.42158622887203256,0.7430608810149629,0.8485377081326498,-0.019893426729216315,0.26882156691646053,0.04733436242856619,1.6057075498374067,0.8905035560094133,-0.5719634057535422,-0.36182891654219795,-0.1554820011028002 | 3,053 |
Negative regulation of rna catabolic process | 9 | 29 | 2.039007 | 0.041449 | Q14103,O95453,P35637,Q13148,Q99729,P98175,O60506,Q92804,Q9H814 | Processes and pathways | GO Biological process | msigdb_gobp | 451,469,137,517,430,358,212,154,321 | 212,1971,1146,469,2455,1313,137,2186,2068,358,1560,850,1600,851,517,829,518,451,1437,1021,1327,154,430,2237,2344,1855,321,1995,1658 | 1.3846557563241517,-0.36182891654219795,0.15856954701810255,0.8064441353972578,-0.6666471270313368,0.04733436242856619,1.724944276613307,-0.47808490468523474,-0.4081884661759546,1.0156498223536288,-0.11011503607208795,0.3998733474246863,-0.13277690412101875,0.3998733474246863,0.7430608810149629,0.42158622887203256,0.7430608810149629,0.8485377081326498,-0.019893426729216315,0.26882156691646053,0.04733436242856619,1.6057075498374067,0.8905035560094133,-0.501480515213417,-0.5719634057535422,-0.2696675832309689,1.0984691394737887,-0.36182891654219795,-0.1554820011028002 | 3,053 |
Motor axonal neuropathy | 7 | 15 | 2.024106 | 0.042959 | P22626,O95831,Q9BTW9,O15269,Q9NRG9,O60313,Q6DD88 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 391,268,544,249,352,402,474 | 249,653,402,268,2509,1344,391,1876,2549,474,1727,1399,544,352,1413 | 1.262689863668224,0.5725751879550428,0.9323432018484419,1.2013248973084056,-0.7142996591987354,0.02496624326774895,0.9532161662596518,-0.29263911521091057,-0.7382051822514453,0.8064441353972578,-0.20102320141396507,0.0025570802874198603,0.7218675610316574,1.036399894714161,0.0025570802874198603 | 3,053 |
Ankyrin repeat [IPR002110] | 7 | 17 | 2.012984 | 0.044116 | Q6W2J9,O75832,Q9H6S0,Q8IUH4,Q9ULT8,Q92625,Q12955 | Sequence | InterPro Repeat | interpro_repeat | 65,598,301,12,675,412,506 | 1085,1308,598,2480,506,912,65,12,412,2034,1262,2039,301,1000,711,2159,675 | 0.20278640880196533,0.04733436242856619,0.6367609840083165,-0.6904471283524107,0.7642212825740413,0.3563379335731602,2.2889304994100175,3.8432367226477653,0.9323432018484419,-0.38498514034941356,0.09194865127890278,-0.38498514034941356,1.1396995480631378,0.2907569811734416,0.5296119487856337,-0.45473795795566646,0.5725751879550428 | 3,053 |
Chromosome segregation | 56 | 134 | 2.012536 | 0.044164 | Q92889,P25054,Q15050,Q53EZ4,Q96SB8,P30260,P61160,P14635,P18074,Q9UJX2,Q9Y6X3,Q9BTX1,Q8NBT2,Q9BV86,Q9ULX6,O60566,O43663,Q9BTE3,Q9Y266,P50748,Q9Y6G9,Q9UJX3,Q8IY18,Q9P258,Q96T76,Q15003,Q96SB4,Q9HD42,P37198,Q9H0H5,Q15005,O94901,Q14671,Q86Y91,Q8TD19,Q7Z5K2,P30153,O43823,Q14807,Q29RF7,Q69YH5,Q86UE8,Q8WUM4,Q9H4L7,Q12834,Q92791,P46379,O00571,P53350,Q96MF7,Q15021,Q02241,Q15018,P38398,Q8NFH4,Q9BZD4 | Processes and pathways | GO Biological process | msigdb_gobp | 781,258,776,409,809,658,660,795,285,693,41,43,297,48,181,550,679,310,576,183,443,188,570,712,319,452,704,199,324,590,204,206,583,479,611,606,346,223,471,603,100,101,750,238,359,494,120,737,490,386,244,743,747,624,645,650 | 737,842,1707,679,2172,223,1217,2216,550,2273,2782,2707,1512,206,2756,2093,1712,2511,2322,2607,795,285,2386,2544,846,1630,258,346,658,1275,1878,324,624,2651,1319,1277,120,2287,183,490,2288,2806,660,1348,1560,743,2430,359,1460,801,853,1491,2261,583,1379,2777,471,2397,2262,452,204,747,244,776,1076,990,603,409,2657,100,2075,1442,606,101,479,570,2146,297,1927,645,611,750,2405,2676,494,781,963,2836,1294,1177,1849,1814,2034,386,704,809,319,2779,1498,1361,310,43,48,1265,1299,893,650,2118,590,965,2448,238,2924,1333,199,1139,1898,2345,3034,1267,712,2085,693,188,1619,181,2622,2780,1862,576,2165,1904,443,41 | 0.48650845797534237,0.3998733474246863,-0.20102320141396507,0.5511109868815428,-0.47808490468523474,1.3441122067215945,0.11419540272429664,-0.501480515213417,0.7006411186565148,-0.5484193521639549,-1.0540235788334475,-0.9314150499140011,-0.08749607248094354,1.4048861540431081,-1.0048032596858985,-0.4314392761759522,-0.20102320141396507,-0.7142996591987354,-0.5719634057535422,-0.8102444399713625,0.443262882592413,1.1602705337166455,-0.6192028971632252,-0.7382051822514453,0.3998733474246863,-0.1554820011028002,1.2422635378120828,1.036399894714161,0.5725751879550428,0.06966173419709126,-0.29263911521091057,1.077809379742811,0.6153999674831028,-0.8585443854221945,0.04733436242856619,0.06966173419709126,1.803929707635828,-0.5484193521639549,1.4855353300607983,0.7853489674913086,-0.5484193521639549,-1.078723901896545,0.5725751879550428,0.02496624326774895,-0.11011503607208795,0.48650845797534237,-0.6428991995691181,1.0156498223536288,-0.04238558185808609,0.443262882592413,0.3998733474246863,-0.06491969310546976,-0.524925194185422,0.6580880397299336,0.0025570802874198603,-1.0293835579205086,0.8064441353972578,-0.6192028971632252,-0.524925194185422,0.8485377081326498,1.4250891645523671,0.48650845797534237,1.2830877377617704,0.4649035470490806,0.22483654434088843,0.2907569811734416,0.6367609840083165,0.9323432018484419,-0.8585443854221945,1.9412079120317214,-0.4081884661759546,-0.019893426729216315,0.6367609840083165,1.9412079120317214,0.8064441353972578,0.6793813477027839,-0.45473795795566646,1.1396995480631378,-0.3156562729795899,0.5940047747374697,0.6367609840083165,0.48650845797534237,-0.6192028971632252,-0.8827779909790987,0.7853489674913086,0.4649035470490806,0.31265467698410715,-1.1283078220968537,0.06966173419709126,0.15856954701810255,-0.2696675832309689,-0.24674132056841452,-0.38498514034941356,0.9740581370180955,0.5296119487856337,0.443262882592413,1.0984691394737887,-1.0293835579205086,-0.06491969310546976,0.02496624326774895,1.1190991391688916,2.6482659504229598,2.554434984977978,0.09194865127890278,0.06966173419709126,0.3781239970118069,0.5940047747374697,-0.4314392761759522,0.6580880397299336,0.31265467698410715,-0.6428991995691181,1.3034573165650833,-1.4055984013294358,0.04733436242856619,1.4452649342552104,0.1806975002667812,-0.29263911521091057,-0.5719634057535422,-2.845806879062828,0.09194865127890278,0.5296119487856337,-0.4081884661759546,0.5511109868815428,1.4654136081925186,-0.13277690412101875,1.5056302422299026,-0.8102444399713625,-1.0293835579205086,-0.2696675832309689,0.6793813477027839,-0.45473795795566646,-0.29263911521091057,0.8695365017538665,2.666971287553807 | 3,053 |
Arthrogryposis multiplex congenita | 12 | 31 | 2.00853 | 0.044587 | Q00535,Q15392,P18074,Q9HD42,O75844,Q96AY3,Q53EZ4,O43175,Q9BTW9,Q9UPT5,P40763,Q8TD19 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 379,4,285,199,45,46,409,18,544,548,405,611 | 2685,18,45,2738,1311,1783,285,2131,405,1750,379,1520,1017,1797,1919,2716,4,409,611,2700,1966,46,2732,631,544,2527,199,836,548,2907,2918 | -0.90706803754792,3.4712462788072194,2.5920285763758244,-0.9802821143207153,0.04733436242856619,-0.24674132056841452,1.1602705337166455,-0.45473795795566646,0.9323432018484419,-0.22385997559133067,0.9740581370180955,-0.08749607248094354,0.26882156691646053,-0.24674132056841452,-0.3156562729795899,-0.9314150499140011,5.036022265834179,0.9323432018484419,0.6367609840083165,-0.90706803754792,-0.3387194179434577,2.5920285763758244,-0.9558195614505496,0.6153999674831028,0.7218675610316574,-0.7142996591987354,1.4452649342552104,0.42158622887203256,0.7218675610316574,-1.3291786390974751,-1.3545835464867986 | 3,053 |
Biological oxidations | 7 | 41 | 1.999278 | 0.045578 | P07099,Q9NUJ1,O43169,Q06520,Q8TB61,O15217,Q16850 | Processes and pathways | Reactome Pathways | msigdb_reactome | 1,38,7,14,178,86,153 | 400,86,7,765,1868,2583,3024,2586,2562,529,1,1975,2382,2786,2485,822,906,225,2666,1483,2952,2220,2726,1117,14,629,153,2717,1465,1052,178,751,1398,2234,2235,589,2526,38,2795,1823,2636 | 0.9323432018484419,2.0966674446159113,4.311451611231286,0.4649035470490806,-0.29263911521091057,-0.7861770917100085,-2.4929274830098986,-0.7861770917100085,-0.7621641673616228,0.7218675610316574,6.024975532201687,-0.36182891654219795,-0.6192028971632252,-1.0540235788334475,-0.6904471283524107,0.42158622887203256,0.3563379335731602,1.3441122067215945,-0.8827779909790987,-0.06491969310546976,-1.534366639104802,-0.501480515213417,-0.9558195614505496,0.1806975002667812,3.666989822854212,0.6153999674831028,1.6057075498374067,-0.9314150499140011,-0.04238558185808609,0.24684817531299486,1.5056302422299026,0.48650845797534237,0.0025570802874198603,-0.501480515213417,-0.501480515213417,0.6580880397299336,-0.7142996591987354,2.704321796591663,-1.0540235788334475,-0.24674132056841452,-0.8343667044836434 | 3,053 |
Negative regulation of cell projection organization | 9 | 28 | 1.999152 | 0.045592 | Q00535,Q9Y4G8,Q15375,Q8N0X7,P47756,Q9NQC3,Q9UL15,Q86X55,Q96G23 | Processes and pathways | GO Biological process | msigdb_gobp | 379,39,396,77,553,312,253,350,29 | 2581,2891,1312,2360,1949,2609,567,2062,553,2103,1485,985,1458,379,1679,1841,2069,1017,1254,396,350,77,1328,29,312,2530,253,39 | -0.7861770917100085,-1.303841118998535,0.04733436242856619,-0.5955577777283037,-0.3387194179434577,-0.8102444399713625,0.6793813477027839,-0.4081884661759546,0.7006411186565148,-0.4314392761759522,-0.06491969310546976,0.2907569811734416,-0.04238558185808609,0.9740581370180955,-0.17823065580578884,-0.2696675832309689,-0.4081884661759546,0.26882156691646053,0.09194865127890278,0.9532161662596518,1.036399894714161,2.1738423843041677,0.04733436242856619,2.9451879305659427,1.1190991391688916,-0.7142996591987354,1.262689863668224,2.6856565412040596 | 3,053 |
Intrinsic component of mitochondrial membrane | 16 | 41 | 1.993052 | 0.046256 | Q9HC21,Q9Y2R0,Q9NVH1,Q9UG56,O14925,Q9H3K2,Q9NX63,Q8IWA4,P12235,Q15070,Q99595,Q16134,O96008,Q6P4A7,O60830,Q5XKP0 | Localization | GO Cellular component | msigdb_gocc | 103,201,432,343,513,272,710,341,488,628,51,584,369,539,24,538 | 513,2049,24,2688,2052,1746,369,488,2871,1071,698,1322,1119,628,957,584,1351,1386,538,539,1126,341,1022,2144,1534,2301,1690,51,2343,2597,2764,272,1856,103,432,710,343,1998,201,2211,926 | 0.7430608810149629,-0.4081884661759546,3.2734630387792905,-0.90706803754792,-0.4081884661759546,-0.22385997559133067,0.9948692957811976,0.7853489674913086,-1.2282259143903864,0.22483654434088843,0.5296119487856337,0.04733436242856619,0.1806975002667812,0.6153999674831028,0.31265467698410715,0.6580880397299336,0.02496624326774895,0.0025570802874198603,0.7218675610316574,0.7218675610316574,0.1806975002667812,1.0571196890420318,0.26882156691646053,-0.45473795795566646,-0.08749607248094354,-0.5484193521639549,-0.17823065580578884,2.5167589592971633,-0.5719634057535422,-0.7861770917100085,-1.0048032596858985,1.2013248973084056,-0.2696675832309689,1.9412079120317214,0.8905035560094133,0.5296119487856337,1.0571196890420318,-0.36182891654219795,1.4452649342552104,-0.47808490468523474,0.3563379335731602 | 3,053 |
Central scotoma | 6 | 10 | 1.986238 | 0.047007 | O00429,O75306,P03915,P03886,Q9H061,O60313 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 315,228,487,177,23,402 | 315,402,228,177,487,2666,646,23,895,1365 | 1.0984691394737887,0.9323432018484419,1.3237987550526746,1.5056302422299026,0.7853489674913086,-0.8827779909790987,0.5940047747374697,3.291529859154659,0.3781239970118069,0.02496624326774895 | 3,053 |
Mitochondrial fission | 6 | 13 | 1.98322 | 0.047343 | O00429,O00203,Q9NUQ9,Q9UDX5,P11233,O60313 | Processes and pathways | GO Biological process | msigdb_gobp | 315,597,113,84,242,402 | 597,315,716,402,242,1121,1534,2301,1645,1330,113,2449,84 | 0.6367609840083165,1.0984691394737887,0.5080778484189623,0.9323432018484419,1.2830877377617704,0.1806975002667812,-0.08749607248094354,-0.5484193521639549,-0.1554820011028002,0.04733436242856619,1.882519935756883,-0.6428991995691181,2.1353004258067396 | 3,053 |
Bone pain | 6 | 25 | 1.970876 | 0.048738 | Q6W2J9,P22681,Q13501,Q9NZJ7,O75874,P48735 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 65,234,47,354,90,121 | 972,90,1311,2417,2250,1831,234,405,121,1792,1881,2549,1377,744,47,1756,2262,1125,1529,65,609,2794,354,1739,867 | 0.2907569811734416,2.0385454239533916,0.04733436242856619,-0.6428991995691181,-0.524925194185422,-0.2696675832309689,1.3034573165650833,0.9323432018484419,1.803929707635828,-0.24674132056841452,-0.29263911521091057,-0.7382051822514453,0.0025570802874198603,0.48650845797534237,2.573242040306225,-0.22385997559133067,-0.524925194185422,0.1806975002667812,-0.08749607248094354,2.2889304994100175,0.6367609840083165,-1.0540235788334475,1.036399894714161,-0.20102320141396507,0.3998733474246863 | 3,053 |
Insulin receptor signaling pathway | 6 | 32 | 1.968786 | 0.048978 | P25054,P43490,P49815,Q9UQB8,P31751,O14654 | Processes and pathways | GO Biological process | msigdb_gobp | 258,2,335,53,116,158 | 1866,158,1009,821,638,357,1452,1190,978,258,1950,116,2,335,1790,1094,2069,1377,2432,1988,477,607,2443,860,3020,2341,1358,1540,2041,2042,53,1247 | -0.29263911521091057,1.5657555247047086,0.26882156691646053,0.42158622887203256,0.5940047747374697,1.0156498223536288,-0.04238558185808609,0.13640227399311802,0.2907569811734416,1.2422635378120828,-0.3387194179434577,1.8432737329874895,5.640916361417248,1.0571196890420318,-0.24674132056841452,0.20278640880196533,-0.4081884661759546,0.0025570802874198603,-0.6428991995691181,-0.36182891654219795,0.8064441353972578,0.6367609840083165,-0.6428991995691181,0.3998733474246863,-2.3779524292893517,-0.5719634057535422,0.02496624326774895,-0.08749607248094354,-0.38498514034941356,-0.38498514034941356,2.4789997780015374,0.11419540272429664 | 3,053 |
Sloping forehead | 21 | 42 | 1.961339 | 0.04984 | Q92889,Q96KP1,P08243,P23786,O43175,P35606,Q6UVJ0,Q92917,Q6P4I2,O60566,Q86XL3,Q9NXE4,Q96EK5,Q15003,Q9BSJ2,Q08J23,Q9HC21,Q9BXW9,P98175,Q15021,P38398 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 781,648,257,130,18,155,803,419,296,550,55,836,832,452,482,851,103,893,358,244,624 | 868,2767,18,2172,550,2352,2355,257,130,1315,155,624,1426,1155,2520,358,851,1636,452,244,990,1384,2717,296,803,55,2146,781,419,1770,1537,832,648,482,893,2527,1242,2083,103,2121,836,2918 | 0.3781239970118069,-1.0293835579205086,3.4712462788072194,-0.47808490468523474,0.7006411186565148,-0.5955577777283037,-0.5955577777283037,1.2422635378120828,1.7447281172585196,0.04733436242856619,1.585744595846163,0.6153999674831028,-0.019893426729216315,0.15856954701810255,-0.7142996591987354,1.0156498223536288,0.3998733474246863,-0.1554820011028002,0.8485377081326498,1.2830877377617704,0.2907569811734416,0.0025570802874198603,-0.9314150499140011,1.1396995480631378,0.443262882592413,2.4600887755522476,-0.45473795795566646,0.4649035470490806,0.9114390602469016,-0.22385997559133067,-0.08749607248094354,0.42158622887203256,0.5940047747374697,0.8064441353972578,0.3781239970118069,-0.7142996591987354,0.11419540272429664,-0.4081884661759546,1.9412079120317214,-0.4314392761759522,0.42158622887203256,-1.3545835464867986 | 3,053 |
Lipid biosynthesis | 11 | 47 | 3.276565 | 0.001051 | Q9NRX5,Q15392,Q14739,P11498,Q96G23,O00763,Q9NZ01,P35790,Q13085,Q16850,Q9UBM7 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 234,2,35,98,103,85,278,22,118,26,95 | 813,85,1931,1058,2064,1943,1887,98,1557,563,22,329,2281,2790,1144,909,1504,1446,2839,118,2028,35,2079,1648,2,2206,2031,2032,26,1338,2146,1346,885,103,1800,2726,1918,2742,2889,1989,1354,1922,234,278,1048,95,1299 | 0.3481214861512012,1.7563813941642747,-0.23428085042851984,0.1971618513328632,-0.29693790496602795,-0.23428085042851984,-0.20304645994480822,1.6775832397269985,-0.047826189001080696,0.5565914918730328,3.0224487127693447,0.8771624436461539,-0.4229981043898459,-1.0022064159022008,0.16676869031834232,0.28794007013935596,-0.016974318162148477,0.013812862961268305,-1.1334880347917538,1.571307922760105,-0.26557808319442094,2.602836514157032,-0.29693790496602795,-0.07874247734263141,7.067902653089992,-0.3598443150443863,-0.26557808319442094,-0.26557808319442094,2.930653338734813,0.07519205271216686,-0.328360064999706,0.07519205271216686,0.3180647212684595,1.6511453475009386,-0.14076723184203568,-0.8718430660882146,-0.20304645994480822,-0.9043471006881587,-1.2656751571664706,-0.23428085042851984,0.07519205271216686,-0.20304645994480822,1.1046721034501785,0.9915258301454644,0.22748833338166233,1.7039344627087378,0.10578350226676929 | 3,044 |
Transcriptional regulation by runx2 | 15 | 51 | 2.990686 | 0.002784 | P25786,Q14997,O00231,P28070,P11802,P42224,P49721,Q13951,P31751,P28074,P20618,Q99436,P60900,P31749,P63208 | Processes and pathways | Reactome Pathways | msigdb_reactome | 312,434,624,37,327,602,15,142,49,19,141,616,459,341,315 | 624,1057,1302,1485,1189,1068,1494,327,1201,1497,960,141,312,962,1135,1694,2278,634,37,1562,19,1317,341,49,2011,602,2012,1374,910,15,1262,2357,459,1150,1153,1507,1579,315,2606,1271,918,1586,142,434,745,1289,616,1531,2227,2346,1054 | 0.4973760257832683,0.1971618513328632,0.07519205271216686,-0.016974318162148477,0.136309143857803,0.1971618513328632,-0.016974318162148477,0.8771624436461539,0.136309143857803,-0.016974318162148477,0.2577478396839187,1.409322786798099,0.9058659736823905,0.2577478396839187,0.16676869031834232,-0.10972291381533784,-0.4229981043898459,0.4973760257832683,2.5790090186950474,-0.047826189001080696,3.0907836555787225,0.07519205271216686,0.8483844479781932,2.214330584420916,-0.26557808319442094,0.5270188270799904,-0.26557808319442094,0.044535079266585564,0.28794007013935596,3.8164386931189918,0.10578350226676929,-0.4863973353694144,0.6741739876103681,0.16676869031834232,0.16676869031834232,-0.016974318162148477,-0.047826189001080696,0.9058659736823905,-0.7102003873333911,0.10578350226676929,0.28794007013935596,-0.047826189001080696,1.409322786798099,0.7033908346533452,0.4080301119164743,0.10578350226676929,0.5270188270799904,-0.016974318162148477,-0.3598443150443863,-0.4546671593010326,0.22748833338166233 | 3,044 |
Orc1 removal from chromatin | 15 | 49 | 2.957431 | 0.003102 | P25786,Q14997,O00231,P33993,P28070,P24941,P20248,P49721,Q99436,P28074,P20618,O43913,Q9UBD5,P60900,P63208 | Processes and pathways | Reactome Pathways | msigdb_reactome | 312,434,624,509,37,507,561,15,616,19,141,454,115,459,315 | 624,1057,1302,1485,1189,454,1068,960,561,141,507,1204,312,962,1135,1694,634,37,1562,19,733,1699,509,2011,2012,1374,910,15,911,1262,2357,459,1150,1153,1507,1579,315,2606,918,1586,1646,434,745,616,1531,115,2227,1054,1360 | 0.4973760257832683,0.1971618513328632,0.07519205271216686,-0.016974318162148477,0.136309143857803,0.6741739876103681,0.1971618513328632,0.2577478396839187,0.5565914918730328,1.409322786798099,0.6155250604989404,0.136309143857803,0.9058659736823905,0.2577478396839187,0.16676869031834232,-0.10972291381533784,0.4973760257832683,2.5790090186950474,-0.047826189001080696,3.0907836555787225,0.4080301119164743,-0.10972291381533784,0.6155250604989404,-0.26557808319442094,-0.26557808319442094,0.044535079266585564,0.28794007013935596,3.8164386931189918,0.28794007013935596,0.10578350226676929,-0.4863973353694144,0.6741739876103681,0.16676869031834232,0.16676869031834232,-0.016974318162148477,-0.047826189001080696,0.9058659736823905,-0.7102003873333911,0.28794007013935596,-0.047826189001080696,-0.07874247734263141,0.7033908346533452,0.4080301119164743,0.5270188270799904,-0.016974318162148477,1.5980072576548476,-0.3598443150443863,0.22748833338166233,0.07519205271216686 | 3,044 |
Hedgehog off state | 14 | 49 | 2.930169 | 0.003388 | P17612,P04350,P25786,O00231,Q14997,P28070,P48729,P60900,P49721,Q99436,P28074,P20618,Q96J02,P63208 | Processes and pathways | Reactome Pathways | msigdb_reactome | 160,377,312,624,434,37,283,459,15,616,19,141,554,315 | 624,1057,1302,1485,1189,1192,1068,377,1889,1828,160,960,141,312,962,1135,1694,634,37,1562,19,2011,2012,1374,283,910,15,1262,2357,459,1150,1153,1507,1579,315,1637,2606,918,1586,1336,434,745,554,616,1531,1987,1174,2227,1054 | 0.4973760257832683,0.1971618513328632,0.07519205271216686,-0.016974318162148477,0.136309143857803,0.136309143857803,0.1971618513328632,0.7906066000553943,-0.20304645994480822,-0.17187516759377872,1.3546589090705994,0.2577478396839187,1.409322786798099,0.9058659736823905,0.2577478396839187,0.16676869031834232,-0.10972291381533784,0.4973760257832683,2.5790090186950474,-0.047826189001080696,3.0907836555787225,-0.26557808319442094,-0.26557808319442094,0.044535079266585564,0.9630480661374073,0.28794007013935596,3.8164386931189918,0.10578350226676929,-0.4863973353694144,0.6741739876103681,0.16676869031834232,0.16676869031834232,-0.016974318162148477,-0.047826189001080696,0.9058659736823905,-0.07874247734263141,-0.7102003873333911,0.28794007013935596,-0.047826189001080696,0.07519205271216686,0.7033908346533452,0.4080301119164743,0.5860936833169975,0.5270188270799904,-0.016974318162148477,-0.23428085042851984,0.16676869031834232,-0.3598443150443863,0.22748833338166233 | 3,044 |
Lissencephaly | 14 | 49 | 2.757914 | 0.005817 | P23786,Q15392,P98155,O43776,Q16625,P07942,Q9H9S5,Q9BV10,P57081,Q9Y5P6,P13804,P78527,Q96EK5,Q9Y487 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 311,2,132,376,136,169,470,443,174,81,149,316,355,426 | 2309,2349,1754,376,169,2275,149,2658,311,458,2127,2864,1567,536,174,2507,1508,316,132,570,2324,1217,1278,2,2206,666,136,2441,1095,2329,1389,1524,2336,355,992,443,1174,2097,1472,1535,1741,470,1991,1176,1675,1482,426,81,2497 | -0.4546671593010326,-0.4863973353694144,-0.14076723184203568,0.7906066000553943,1.2996673969914763,-0.4229981043898459,1.382032049767132,-0.7746811051942666,0.9058659736823905,0.6741739876103681,-0.328360064999706,-1.1994691886603914,-0.047826189001080696,0.5860936833169975,1.2996673969914763,-0.61392455778647,-0.016974318162148477,0.9058659736823905,1.4906954915337542,0.5565914918730328,-0.4546671593010326,0.136309143857803,0.10578350226676929,7.067902653089992,-0.3598443150443863,0.4676634208377951,1.4636550239775168,-0.550040107796456,0.1971618513328632,-0.4546671593010326,0.044535079266585564,-0.016974318162148477,-0.4546671593010326,0.8483844479781932,0.2577478396839187,0.7033908346533452,0.16676869031834232,-0.29693790496602795,0.013812862961268305,-0.016974318162148477,-0.10972291381533784,0.6741739876103681,-0.23428085042851984,0.16676869031834232,-0.07874247734263141,0.013812862961268305,0.7325354614920672,1.8084948778531584,-0.5819522382011225 | 3,044 |
Degradation of beta catenin by the destruction complex | 14 | 47 | 2.704865 | 0.006833 | P25786,Q14997,O00231,P28070,P30153,P30154,P48729,P25054,P49721,Q99436,P28074,P20618,P60900,P63208 | Processes and pathways | Reactome Pathways | msigdb_reactome | 312,434,624,37,530,508,283,562,15,616,19,141,459,315 | 624,1057,1302,1485,1189,1068,960,141,562,312,962,1135,1694,634,37,1562,19,530,508,1833,2011,2012,1374,283,910,15,1262,2357,2661,459,1150,1153,1507,1579,315,2606,918,1513,1584,1586,1276,434,745,616,1531,2227,1054 | 0.4973760257832683,0.1971618513328632,0.07519205271216686,-0.016974318162148477,0.136309143857803,0.1971618513328632,0.2577478396839187,1.409322786798099,0.5565914918730328,0.9058659736823905,0.2577478396839187,0.16676869031834232,-0.10972291381533784,0.4973760257832683,2.5790090186950474,-0.047826189001080696,3.0907836555787225,0.5860936833169975,0.6155250604989404,-0.17187516759377872,-0.26557808319442094,-0.26557808319442094,0.044535079266585564,0.9630480661374073,0.28794007013935596,3.8164386931189918,0.10578350226676929,-0.4863973353694144,-0.7746811051942666,0.6741739876103681,0.16676869031834232,0.16676869031834232,-0.016974318162148477,-0.047826189001080696,0.9058659736823905,-0.7102003873333911,0.28794007013935596,-0.016974318162148477,-0.047826189001080696,-0.047826189001080696,0.10578350226676929,0.7033908346533452,0.4080301119164743,0.5270188270799904,-0.016974318162148477,-0.3598443150443863,0.22748833338166233 | 3,044 |
Switching of origins to a post replicative state | 17 | 56 | 2.625179 | 0.00866 | P25786,Q14997,O00231,P33993,P28070,P24941,P20248,P49721,Q96DE5,Q99436,P28074,P20618,O43913,Q9UBD5,Q9H1A4,P60900,P63208 | Processes and pathways | Reactome Pathways | msigdb_reactome | 312,434,624,509,37,507,561,15,306,616,19,141,454,115,586,459,315 | 624,1057,1302,1485,1189,454,1068,960,561,141,507,1204,312,962,1135,1694,634,37,1562,19,779,733,1699,509,2011,2012,1374,910,15,911,1262,2357,459,1150,1153,1507,1579,315,2606,918,1586,1646,434,745,1905,306,616,1531,586,115,1118,1184,1876,2227,1054,1360 | 0.4973760257832683,0.1971618513328632,0.07519205271216686,-0.016974318162148477,0.136309143857803,0.6741739876103681,0.1971618513328632,0.2577478396839187,0.5565914918730328,1.409322786798099,0.6155250604989404,0.136309143857803,0.9058659736823905,0.2577478396839187,0.16676869031834232,-0.10972291381533784,0.4973760257832683,2.5790090186950474,-0.047826189001080696,3.0907836555787225,0.3781100543642303,0.4080301119164743,-0.10972291381533784,0.6155250604989404,-0.26557808319442094,-0.26557808319442094,0.044535079266585564,0.28794007013935596,3.8164386931189918,0.28794007013935596,0.10578350226676929,-0.4863973353694144,0.6741739876103681,0.16676869031834232,0.16676869031834232,-0.016974318162148477,-0.047826189001080696,0.9058659736823905,-0.7102003873333911,0.28794007013935596,-0.047826189001080696,-0.07874247734263141,0.7033908346533452,0.4080301119164743,-0.20304645994480822,0.9344946467002561,0.5270188270799904,-0.016974318162148477,0.5565914918730328,1.5980072576548476,0.1971618513328632,0.16676869031834232,-0.17187516759377872,-0.3598443150443863,0.22748833338166233,0.07519205271216686 | 3,044 |
Regulation of tp53 activity | 17 | 50 | 2.546234 | 0.010889 | O14744,P30153,Q9NRG4,P30154,P24941,P40937,P20248,Q92804,Q12873,Q92547,O94776,P31751,Q9UQ84,Q9NPI1,Q13526,P31749,P42345 | Processes and pathways | Reactome Pathways | msigdb_reactome | 557,530,6,508,507,535,561,73,208,579,482,49,21,54,318,341,246 | 557,1545,1547,2628,482,1687,1245,1612,1494,1202,2503,561,507,821,530,508,341,49,1437,1438,2281,535,736,246,2954,1573,826,1446,662,570,1970,208,318,1584,1277,1854,579,1596,73,2298,845,2832,2593,2782,54,6,2567,21,2167,1676 | 0.5565914918730328,-0.047826189001080696,-0.047826189001080696,-0.7424112098929048,0.6448852783592486,-0.10972291381533784,0.10578350226676929,-0.07874247734263141,-0.016974318162148477,0.136309143857803,-0.61392455778647,0.5565914918730328,0.6155250604989404,0.3481214861512012,0.5860936833169975,0.6155250604989404,0.8483844479781932,2.214330584420916,0.013812862961268305,0.013812862961268305,-0.4229981043898459,0.5860936833169975,0.4080301119164743,1.0482527573655716,-1.566343719113424,-0.047826189001080696,0.3481214861512012,0.013812862961268305,0.4676634208377951,0.5565914918730328,-0.23428085042851984,1.160780451278084,0.9058659736823905,-0.047826189001080696,0.10578350226676929,-0.17187516759377872,0.5565914918730328,-0.047826189001080696,1.886058061628008,-0.4229981043898459,0.3481214861512012,-1.1005822480638625,-0.6780488566603873,-0.9695289821825922,2.164611651394882,5.250604250509582,-0.645956839059224,3.068053237517981,-0.328360064999706,-0.07874247734263141 | 3,044 |
Biological oxidations | 9 | 41 | 2.532046 | 0.01134 | P07099,Q8WUX2,Q86WA6,Q9NUJ1,Q06520,O15217,P21266,P30837,Q16850 | Processes and pathways | Reactome Pathways | msigdb_reactome | 4,228,200,148,16,17,46,111,26 | 1999,17,1934,279,1362,2569,1191,2117,1887,2065,4,2314,1431,2422,1251,1891,46,730,2237,1203,111,1319,2537,1967,16,1648,26,2663,2364,200,1593,228,2217,2218,407,1043,2687,148,898,858,2856 | -0.26557808319442094,3.4482840836492654,-0.23428085042851984,0.9630480661374073,0.044535079266585564,-0.6780488566603873,0.136309143857803,-0.328360064999706,-0.20304645994480822,-0.29693790496602795,5.927575511555,-0.4546671593010326,0.013812862961268305,-0.550040107796456,0.10578350226676929,-0.20304645994480822,2.2637799306174515,0.4080301119164743,-0.3913904093021849,0.136309143857803,1.5980072576548476,0.07519205271216686,-0.645956839059224,-0.23428085042851984,3.514085926832498,-0.07874247734263141,2.930653338734813,-0.7746811051942666,-0.4863973353694144,1.188716906763166,-0.047826189001080696,1.1046721034501785,-0.3598443150443863,-0.3598443150443863,0.7616075056451529,0.22748833338166233,-0.8070098561035425,1.409322786798099,0.3180647212684595,0.3481214861512012,-1.16645041336952 | 3,044 |
Signaling by the b cell receptor bcr | 14 | 47 | 2.52901 | 0.011438 | P25786,Q14997,O00231,P28070,P16333,O43865,P49721,Q99436,P28074,P20618,P62942,P60900,Q08209,P63208 | Processes and pathways | Reactome Pathways | msigdb_reactome | 312,434,624,37,631,479,15,616,19,141,488,459,542,315 | 624,1057,1302,1485,1060,2001,1189,479,1068,2750,1822,631,960,141,312,962,1135,1694,634,37,1562,19,2011,2012,1374,910,15,1262,2357,459,1150,1153,1507,1579,488,1328,315,2606,542,918,1586,434,745,616,1531,2227,1054 | 0.4973760257832683,0.1971618513328632,0.07519205271216686,-0.016974318162148477,0.1971618513328632,-0.26557808319442094,0.136309143857803,0.6448852783592486,0.1971618513328632,-0.9369091418892902,-0.17187516759377872,0.4973760257832683,0.2577478396839187,1.409322786798099,0.9058659736823905,0.2577478396839187,0.16676869031834232,-0.10972291381533784,0.4973760257832683,2.5790090186950474,-0.047826189001080696,3.0907836555787225,-0.26557808319442094,-0.26557808319442094,0.044535079266585564,0.28794007013935596,3.8164386931189918,0.10578350226676929,-0.4863973353694144,0.6741739876103681,0.16676869031834232,0.16676869031834232,-0.016974318162148477,-0.047826189001080696,0.6448852783592486,0.07519205271216686,0.9058659736823905,-0.7102003873333911,0.5860936833169975,0.28794007013935596,-0.047826189001080696,0.7033908346533452,0.4080301119164743,0.5270188270799904,-0.016974318162148477,-0.3598443150443863,0.22748833338166233 | 3,044 |
Cyclin a cdk2 associated events at s phase entry | 14 | 42 | 2.515012 | 0.011903 | P25786,O00231,P28070,P24941,P20248,P11802,P49721,P31751,P28074,P20618,Q99436,P60900,P31749,P63208 | Processes and pathways | Reactome Pathways | msigdb_reactome | 312,624,37,507,561,327,15,49,19,141,616,459,341,315 | 624,1057,1302,1485,1189,1068,327,960,561,141,507,312,962,1135,1694,634,37,1562,19,341,49,2011,2012,1374,910,15,1262,2357,459,1150,1153,1507,1579,315,2606,918,1586,745,616,1531,2227,1054 | 0.4973760257832683,0.1971618513328632,0.07519205271216686,-0.016974318162148477,0.136309143857803,0.1971618513328632,0.8771624436461539,0.2577478396839187,0.5565914918730328,1.409322786798099,0.6155250604989404,0.9058659736823905,0.2577478396839187,0.16676869031834232,-0.10972291381533784,0.4973760257832683,2.5790090186950474,-0.047826189001080696,3.0907836555787225,0.8483844479781932,2.214330584420916,-0.26557808319442094,-0.26557808319442094,0.044535079266585564,0.28794007013935596,3.8164386931189918,0.10578350226676929,-0.4863973353694144,0.6741739876103681,0.16676869031834232,0.16676869031834232,-0.016974318162148477,-0.047826189001080696,0.9058659736823905,-0.7102003873333911,0.28794007013935596,-0.047826189001080696,0.4080301119164743,0.5270188270799904,-0.016974318162148477,-0.3598443150443863,0.22748833338166233 | 3,044 |
Metabolism of vitamins and cofactors | 14 | 46 | 2.466658 | 0.013638 | P11498,P05165,P41440,P34897,Q96RQ3,O75874,Q4G0N4,O00763,O14678,Q9NVE7,Q13085,P50747,Q9NRN7,P43490 | Processes and pathways | Reactome Pathways | msigdb_reactome | 98,101,39,138,76,203,119,85,86,256,118,59,193,29 | 85,2909,86,203,596,1887,2771,2927,101,1614,2573,818,98,1618,2007,2424,341,245,138,2186,39,29,909,59,1967,2285,2825,118,119,643,2294,2144,2878,2484,439,2642,76,1043,469,1991,1743,1537,1296,193,256,2933 | 1.7563813941642747,-1.36540230172939,1.7563813941642747,1.160780451278084,0.5270188270799904,-0.20304645994480822,-0.9695289821825922,-1.432163677429818,1.6511453475009386,-0.07874247734263141,-0.6780488566603873,0.3481214861512012,1.6775832397269985,-0.07874247734263141,-0.26557808319442094,-0.550040107796456,0.8483844479781932,1.0482527573655716,1.4365306156375974,-0.3598443150443863,2.386261231789582,2.768057588529076,0.28794007013935596,2.114617131220128,-0.23428085042851984,-0.4229981043898459,-1.1005822480638625,1.571307922760105,1.571307922760105,0.4973760257832683,-0.4229981043898459,-0.328360064999706,-1.2325441671985713,-0.5819522382011225,0.7033908346533452,-0.7424112098929048,1.860283266571758,0.22748833338166233,0.6741739876103681,-0.23428085042851984,-0.10972291381533784,-0.016974318162148477,0.10578350226676929,1.2165742873577703,1.0482527573655716,-1.432163677429818 | 3,044 |
Signaling by hedgehog | 14 | 54 | 2.427924 | 0.015186 | P17612,P04350,P25786,O00231,Q14997,P28070,P48729,P60900,P49721,Q99436,P28074,P20618,Q96J02,P63208 | Processes and pathways | Reactome Pathways | msigdb_reactome | 160,377,312,624,434,37,283,459,15,616,19,141,554,315 | 624,1057,1302,1485,1189,1192,1068,377,1616,1889,1828,160,960,141,312,962,1135,1694,634,37,1562,19,2011,2012,1374,283,910,15,1262,2357,1839,459,1150,1153,1507,1579,315,1637,2606,918,1586,1023,1336,434,745,1727,554,616,1531,1987,1174,2709,2227,1054 | 0.4973760257832683,0.1971618513328632,0.07519205271216686,-0.016974318162148477,0.136309143857803,0.136309143857803,0.1971618513328632,0.7906066000553943,-0.07874247734263141,-0.20304645994480822,-0.17187516759377872,1.3546589090705994,0.2577478396839187,1.409322786798099,0.9058659736823905,0.2577478396839187,0.16676869031834232,-0.10972291381533784,0.4973760257832683,2.5790090186950474,-0.047826189001080696,3.0907836555787225,-0.26557808319442094,-0.26557808319442094,0.044535079266585564,0.9630480661374073,0.28794007013935596,3.8164386931189918,0.10578350226676929,-0.4863973353694144,-0.17187516759377872,0.6741739876103681,0.16676869031834232,0.16676869031834232,-0.016974318162148477,-0.047826189001080696,0.9058659736823905,-0.07874247734263141,-0.7102003873333911,0.28794007013935596,-0.047826189001080696,0.22748833338166233,0.07519205271216686,0.7033908346533452,0.4080301119164743,-0.10972291381533784,0.5860936833169975,0.5270188270799904,-0.016974318162148477,-0.23428085042851984,0.16676869031834232,-0.8393972474681705,-0.3598443150443863,0.22748833338166233 | 3,044 |
Cupped ear | 7 | 15 | 2.425718 | 0.015278 | Q15392,P78318,Q2TAL8,Q93074,O60828,Q6W2J9,P52788 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 2,42,348,175,358,351,432 | 358,1688,1141,432,1635,42,1640,1277,2,348,1386,351,2085,175,499 | 0.8195323729966623,-0.10972291381533784,0.16676869031834232,0.7033908346533452,-0.07874247734263141,2.337461049336215,-0.07874247734263141,0.10578350226676929,7.067902653089992,0.8483844479781932,0.044535079266585564,0.8483844479781932,-0.29693790496602795,1.2996673969914763,0.6448852783592486 | 3,044 |
Beta catenin independent wnt signaling | 13 | 50 | 2.402081 | 0.016302 | P25786,Q14997,O00231,P28070,P61586,Q96CW1,P49721,Q99436,P28074,P20618,P60900,Q08209,Q9HCE1 | Processes and pathways | Reactome Pathways | msigdb_reactome | 312,434,624,37,538,467,15,616,19,141,459,542,423 | 624,1057,1302,1485,1189,1068,1009,1495,1370,2597,960,141,312,962,1135,1694,634,37,1562,19,1833,2011,2012,1374,910,15,1262,1443,2357,459,1150,538,1153,1507,1579,2017,1714,701,2606,542,918,1089,434,745,467,616,1531,423,2227,1054 | 0.4973760257832683,0.1971618513328632,0.07519205271216686,-0.016974318162148477,0.136309143857803,0.1971618513328632,0.22748833338166233,-0.016974318162148477,0.044535079266585564,-0.7102003873333911,0.2577478396839187,1.409322786798099,0.9058659736823905,0.2577478396839187,0.16676869031834232,-0.10972291381533784,0.4973760257832683,2.5790090186950474,-0.047826189001080696,3.0907836555787225,-0.17187516759377872,-0.26557808319442094,-0.26557808319442094,0.044535079266585564,0.28794007013935596,3.8164386931189918,0.10578350226676929,0.013812862961268305,-0.4863973353694144,0.6741739876103681,0.16676869031834232,0.5860936833169975,0.16676869031834232,-0.016974318162148477,-0.047826189001080696,-0.26557808319442094,-0.10972291381533784,0.43788134118310246,-0.7102003873333911,0.5860936833169975,0.28794007013935596,0.1971618513328632,0.7033908346533452,0.4080301119164743,0.6741739876103681,0.5270188270799904,-0.016974318162148477,0.7325354614920672,-0.3598443150443863,0.22748833338166233 | 3,044 |
Apc c mediated degradation of cell cycle proteins | 15 | 55 | 2.324896 | 0.020078 | P25786,Q14997,O00231,Q12834,P28070,P24941,P20248,P49721,Q96DE5,Q99436,P28074,P20618,Q9H1A4,P60900,P63208 | Processes and pathways | Reactome Pathways | msigdb_reactome | 312,434,624,607,37,507,561,15,306,616,19,141,586,459,315 | 624,1057,1302,1485,1547,1189,1606,2693,1068,1494,1201,960,561,141,507,312,962,1135,1694,634,37,1562,19,779,2011,2012,1374,910,15,1262,912,2357,459,1150,1153,1507,1579,315,2606,607,918,1643,1586,434,745,1905,306,616,1531,586,1118,1184,1876,2227,1054 | 0.4973760257832683,0.1971618513328632,0.07519205271216686,-0.016974318162148477,-0.047826189001080696,0.136309143857803,-0.07874247734263141,-0.8393972474681705,0.1971618513328632,-0.016974318162148477,0.136309143857803,0.2577478396839187,0.5565914918730328,1.409322786798099,0.6155250604989404,0.9058659736823905,0.2577478396839187,0.16676869031834232,-0.10972291381533784,0.4973760257832683,2.5790090186950474,-0.047826189001080696,3.0907836555787225,0.3781100543642303,-0.26557808319442094,-0.26557808319442094,0.044535079266585564,0.28794007013935596,3.8164386931189918,0.10578350226676929,0.28794007013935596,-0.4863973353694144,0.6741739876103681,0.16676869031834232,0.16676869031834232,-0.016974318162148477,-0.047826189001080696,0.9058659736823905,-0.7102003873333911,0.5270188270799904,0.28794007013935596,-0.07874247734263141,-0.047826189001080696,0.7033908346533452,0.4080301119164743,-0.20304645994480822,0.9344946467002561,0.5270188270799904,-0.016974318162148477,0.5565914918730328,0.1971618513328632,0.16676869031834232,-0.17187516759377872,-0.3598443150443863,0.22748833338166233 | 3,044 |
Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1 | 12 | 46 | 2.320735 | 0.020301 | P25786,Q14997,O00231,Q12834,P28070,P49721,Q96DE5,Q99436,P28074,P20618,Q9H1A4,P60900 | Processes and pathways | Reactome Pathways | msigdb_reactome | 312,434,624,607,37,15,306,616,19,141,586,459 | 624,1057,1302,1485,1547,1189,1068,960,141,312,962,1135,1694,634,37,1562,19,779,2011,2012,1374,910,15,1262,912,2357,459,1150,1153,1507,1579,2606,607,918,434,745,1905,306,616,1531,586,1118,1184,1876,2227,1054 | 0.4973760257832683,0.1971618513328632,0.07519205271216686,-0.016974318162148477,-0.047826189001080696,0.136309143857803,0.1971618513328632,0.2577478396839187,1.409322786798099,0.9058659736823905,0.2577478396839187,0.16676869031834232,-0.10972291381533784,0.4973760257832683,2.5790090186950474,-0.047826189001080696,3.0907836555787225,0.3781100543642303,-0.26557808319442094,-0.26557808319442094,0.044535079266585564,0.28794007013935596,3.8164386931189918,0.10578350226676929,0.28794007013935596,-0.4863973353694144,0.6741739876103681,0.16676869031834232,0.16676869031834232,-0.016974318162148477,-0.047826189001080696,-0.7102003873333911,0.5270188270799904,0.28794007013935596,0.7033908346533452,0.4080301119164743,-0.20304645994480822,0.9344946467002561,0.5270188270799904,-0.016974318162148477,0.5565914918730328,0.1971618513328632,0.16676869031834232,-0.17187516759377872,-0.3598443150443863,0.22748833338166233 | 3,044 |
non-receptor serine/threonine protein kinase | 20 | 49 | 2.313881 | 0.020674 | Q9UHY1,P24941,P17612,P78362,P48729,P50750,Q96KB5,P31751,P78527,Q86UE8,P11802,Q00535,Q13418,P31749,Q9Y4A5,Q8IV63,Q05655,Q15120,Q13555,P42345 | Functions | Panther Protein class | panther_protein_class | 133,507,160,285,283,45,581,49,316,70,327,570,572,341,236,365,490,385,248,246 | 1545,1060,1547,2001,2693,1065,1245,1494,327,160,1134,2124,507,2278,1317,341,49,2010,246,1569,283,2190,45,912,285,316,570,1087,490,917,1512,572,2325,641,248,2480,385,2945,749,70,365,2869,581,939,1467,2261,2977,133,236 | -0.047826189001080696,0.1971618513328632,-0.047826189001080696,-0.26557808319442094,-0.8393972474681705,0.1971618513328632,0.10578350226676929,-0.016974318162148477,0.8771624436461539,1.3546589090705994,0.16676869031834232,-0.328360064999706,0.6155250604989404,-0.4229981043898459,0.07519205271216686,0.8483844479781932,2.214330584420916,-0.26557808319442094,1.0482527573655716,-0.047826189001080696,0.9630480661374073,-0.3598443150443863,2.288405321878791,0.28794007013935596,0.9630480661374073,0.9058659736823905,0.5565914918730328,0.1971618513328632,0.6448852783592486,0.28794007013935596,-0.016974318162148477,0.5565914918730328,-0.4546671593010326,0.4973760257832683,1.0482527573655716,-0.5819522382011225,0.7906066000553943,-1.4991446302853906,0.4080301119164743,1.9373736887133322,0.8195323729966623,-1.1994691886603914,0.5565914918730328,0.28794007013935596,0.013812862961268305,-0.3913904093021849,-1.7013906562683296,1.4906954915337542,1.1046721034501785 | 3,044 |
Metabolism of water soluble vitamins and cofactors | 13 | 35 | 2.312927 | 0.020727 | P11498,P05165,P41440,P34897,Q96RQ3,O00763,O14678,Q4G0N4,Q9NVE7,Q13085,P50747,Q9NRN7,P43490 | Processes and pathways | Reactome Pathways | msigdb_reactome | 98,101,39,138,76,85,86,119,256,118,59,193,29 | 85,2909,86,596,1887,101,1614,818,98,1618,2007,2424,245,138,39,29,909,59,1967,118,119,2294,2878,2484,2642,76,1043,469,1991,1743,1537,1296,193,256,2933 | 1.7563813941642747,-1.36540230172939,1.7563813941642747,0.5270188270799904,-0.20304645994480822,1.6511453475009386,-0.07874247734263141,0.3481214861512012,1.6775832397269985,-0.07874247734263141,-0.26557808319442094,-0.550040107796456,1.0482527573655716,1.4365306156375974,2.386261231789582,2.768057588529076,0.28794007013935596,2.114617131220128,-0.23428085042851984,1.571307922760105,1.571307922760105,-0.4229981043898459,-1.2325441671985713,-0.5819522382011225,-0.7424112098929048,1.860283266571758,0.22748833338166233,0.6741739876103681,-0.23428085042851984,-0.10972291381533784,-0.016974318162148477,0.10578350226676929,1.2165742873577703,1.0482527573655716,-1.432163677429818 | 3,044 |
The role of gtse1 in g2 m progression after g2 checkpoint | 11 | 49 | 2.297912 | 0.021567 | P25786,P04350,Q14997,O00231,P28070,P49721,Q99436,P28074,P20618,P60900,O95067 | Processes and pathways | Reactome Pathways | msigdb_reactome | 312,377,434,624,37,15,616,19,141,459,159 | 624,1057,1302,1485,1189,1068,159,377,1612,1494,2573,2314,1201,960,141,312,962,1135,1694,634,37,1562,19,2011,2012,1374,910,15,1262,912,2357,459,1150,1153,1507,1579,1637,2606,918,1336,434,745,977,616,1531,1987,1174,2227,1054 | 0.4973760257832683,0.1971618513328632,0.07519205271216686,-0.016974318162148477,0.136309143857803,0.1971618513328632,1.3546589090705994,0.7906066000553943,-0.07874247734263141,-0.016974318162148477,-0.6780488566603873,-0.4546671593010326,0.136309143857803,0.2577478396839187,1.409322786798099,0.9058659736823905,0.2577478396839187,0.16676869031834232,-0.10972291381533784,0.4973760257832683,2.5790090186950474,-0.047826189001080696,3.0907836555787225,-0.26557808319442094,-0.26557808319442094,0.044535079266585564,0.28794007013935596,3.8164386931189918,0.10578350226676929,0.28794007013935596,-0.4863973353694144,0.6741739876103681,0.16676869031834232,0.16676869031834232,-0.016974318162148477,-0.047826189001080696,-0.07874247734263141,-0.7102003873333911,0.28794007013935596,0.07519205271216686,0.7033908346533452,0.4080301119164743,0.2577478396839187,0.5270188270799904,-0.016974318162148477,-0.23428085042851984,0.16676869031834232,-0.3598443150443863,0.22748833338166233 | 3,044 |
Abnormality of the metaphysis | 15 | 51 | 2.295363 | 0.021712 | Q96MF7,Q14739,Q07864,O95831,P48735,Q13126,A1X283,Q7RTS9,Q99575,Q2TAL8,O75874,Q9H1A4,Q9NUQ7,Q9NPE3,P36776 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 498,35,286,5,135,8,410,10,108,348,203,586,589,619,533 | 410,1678,1550,1817,1424,203,2571,5,1245,1612,2953,1616,2861,2423,1205,533,1571,1144,135,2776,1576,1969,1381,1450,286,2324,8,35,2134,1647,348,1386,10,2297,841,1799,2299,2904,2446,498,108,586,647,619,2260,2744,589,2408,1299,2710,1417 | 0.7325354614920672,-0.10972291381533784,-0.047826189001080696,-0.17187516759377872,0.013812862961268305,1.160780451278084,-0.6780488566603873,5.536190433847666,0.10578350226676929,-0.07874247734263141,-1.566343719113424,-0.07874247734263141,-1.1994691886603914,-0.550040107796456,0.136309143857803,0.5860936833169975,-0.047826189001080696,0.16676869031834232,1.4636550239775168,-0.9695289821825922,-0.047826189001080696,-0.23428085042851984,0.044535079266585564,0.013812862961268305,0.9630480661374073,-0.4546671593010326,4.979142593837443,2.602836514157032,-0.328360064999706,-0.07874247734263141,0.8483844479781932,0.044535079266585564,4.542075388422235,-0.4229981043898459,0.3481214861512012,-0.14076723184203568,-0.4229981043898459,-1.332104412228467,-0.550040107796456,0.6448852783592486,1.6246199234372136,0.5565914918730328,0.4973760257832683,0.5270188270799904,-0.3913904093021849,-0.9043471006881587,0.5565914918730328,-0.5181883962325351,0.10578350226676929,-0.8393972474681705,0.044535079266585564 | 3,044 |
Metapathway biotransformation phase i and ii | 6 | 21 | 2.287081 | 0.022191 | P07099,P21266,Q06520,O15217,Q86UY6,Q16850 | Processes and pathways | WikiPathways | msigdb_wp | 4,46,16,17,112,26 | 1999,17,1362,2569,412,4,1251,1432,46,730,1257,2537,1967,16,26,152,112,2687,714,1921,2856 | -0.26557808319442094,3.4482840836492654,0.044535079266585564,-0.6780488566603873,0.7325354614920672,5.927575511555,0.10578350226676929,0.013812862961268305,2.2637799306174515,0.4080301119164743,0.10578350226676929,-0.645956839059224,-0.23428085042851984,3.514085926832498,2.930653338734813,1.382032049767132,1.5980072576548476,-0.8070098561035425,0.43788134118310246,-0.20304645994480822,-1.16645041336952 | 3,044 |
Clec7a dectin 1 signaling | 13 | 48 | 2.286019 | 0.022253 | P25786,Q14997,O00231,P28070,O43865,Q05655,P49721,Q99436,P28074,P20618,P60900,Q08209,P63208 | Processes and pathways | Reactome Pathways | msigdb_reactome | 312,434,624,37,479,490,15,616,19,141,459,542,315 | 624,1057,1302,1485,1060,2001,1189,479,1068,2750,960,141,312,962,1135,1694,634,37,1562,19,2011,2012,1374,910,15,1262,2357,459,2197,2582,1150,1153,1507,1579,315,490,2606,542,918,1586,434,745,748,1393,616,1531,2227,1054 | 0.4973760257832683,0.1971618513328632,0.07519205271216686,-0.016974318162148477,0.1971618513328632,-0.26557808319442094,0.136309143857803,0.6448852783592486,0.1971618513328632,-0.9369091418892902,0.2577478396839187,1.409322786798099,0.9058659736823905,0.2577478396839187,0.16676869031834232,-0.10972291381533784,0.4973760257832683,2.5790090186950474,-0.047826189001080696,3.0907836555787225,-0.26557808319442094,-0.26557808319442094,0.044535079266585564,0.28794007013935596,3.8164386931189918,0.10578350226676929,-0.4863973353694144,0.6741739876103681,-0.3598443150443863,-0.6780488566603873,0.16676869031834232,0.16676869031834232,-0.016974318162148477,-0.047826189001080696,0.9058659736823905,0.6448852783592486,-0.7102003873333911,0.5860936833169975,0.28794007013935596,-0.047826189001080696,0.7033908346533452,0.4080301119164743,0.4080301119164743,0.044535079266585564,0.5270188270799904,-0.016974318162148477,-0.3598443150443863,0.22748833338166233 | 3,044 |
Peripheral axonal neuropathy | 10 | 47 | 2.27767 | 0.022746 | Q15813,Q15067,O95831,P07384,P34897,Q6DD88,Q15046,P22626,P39210,P03886 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 291,289,5,413,138,43,288,399,24,58 | 1061,411,629,950,691,5,956,58,2715,1195,413,2967,2234,1072,1197,1949,399,1078,138,24,601,2244,2130,1502,1505,1839,1265,1332,2433,1217,288,289,291,43,1225,577,1731,1527,1736,2997,1400,1991,2100,1926,1117,1997,1122 | 0.1971618513328632,0.7325354614920672,0.4973760257832683,0.2577478396839187,0.43788134118310246,5.536190433847666,0.2577478396839187,2.114617131220128,-0.8718430660882146,0.136309143857803,0.7325354614920672,-1.6337595261138573,-0.3913904093021849,0.1971618513328632,0.136309143857803,-0.23428085042851984,0.7616075056451529,0.1971618513328632,1.4365306156375974,2.9995737889502343,0.5270188270799904,-0.3913904093021849,-0.328360064999706,-0.016974318162148477,-0.016974318162148477,-0.17187516759377872,0.10578350226676929,0.07519205271216686,-0.550040107796456,0.136309143857803,0.9630480661374073,0.9630480661374073,0.9630480661374073,2.337461049336215,0.136309143857803,0.5565914918730328,-0.10972291381533784,-0.016974318162148477,-0.10972291381533784,-2.0083590588041704,0.044535079266585564,-0.23428085042851984,-0.29693790496602795,-0.20304645994480822,0.1971618513328632,-0.23428085042851984,0.1971618513328632 | 3,044 |
Sarcoma | 20 | 63 | 2.26954 | 0.023236 | P61313,Q15392,P48735,Q13126,Q01844,P18077,Q9UPY3,Q9H1A4,P46783,P21359,Q12824,P25054,Q92804,O75874,P31749,Q05655,P08708,Q99496,P52701,P49815 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 381,2,135,8,264,660,592,586,184,56,197,562,73,203,341,490,485,644,487,117 | 1547,1606,2693,1758,2628,203,1245,2382,1612,1369,485,1889,660,1950,2423,56,1560,562,1952,341,1833,2390,1960,1624,1570,184,135,909,117,487,1149,2508,381,2074,2583,1634,2429,2478,1843,1510,1580,1640,264,1087,490,1450,741,1271,2825,197,8,881,665,2,835,1727,73,1396,2089,1465,644,586,592 | -0.047826189001080696,-0.07874247734263141,-0.8393972474681705,-0.14076723184203568,-0.7424112098929048,1.160780451278084,0.10578350226676929,-0.5181883962325351,-0.07874247734263141,0.044535079266585564,0.6448852783592486,-0.20304645994480822,0.4676634208377951,-0.23428085042851984,-0.550040107796456,2.1396492238554883,-0.047826189001080696,0.5565914918730328,-0.23428085042851984,0.8483844479781932,-0.17187516759377872,-0.5181883962325351,-0.23428085042851984,-0.07874247734263141,-0.047826189001080696,1.244352138092191,1.4636550239775168,0.28794007013935596,1.571307922760105,0.6448852783592486,0.16676869031834232,-0.61392455778647,0.7906066000553943,-0.29693790496602795,-0.6780488566603873,-0.07874247734263141,-0.550040107796456,-0.5819522382011225,-0.17187516759377872,-0.016974318162148477,-0.047826189001080696,-0.07874247734263141,1.0199275314764034,0.1971618513328632,0.6448852783592486,0.013812862961268305,0.4080301119164743,0.10578350226676929,-1.1005822480638625,1.188716906763166,4.979142593837443,0.3180647212684595,0.4676634208377951,7.067902653089992,0.3481214861512012,-0.10972291381533784,1.886058061628008,0.044535079266585564,-0.29693790496602795,0.013812862961268305,0.4973760257832683,0.5565914918730328,0.5565914918730328 | 3,044 |
Metaphyseal dysplasia | 6 | 12 | 2.226188 | 0.026002 | Q07864,O95831,Q99575,Q7RTS9,Q9NUQ7,P36776 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 286,5,108,10,589,533 | 1678,5,533,1576,286,1386,10,2297,108,647,589,1417 | -0.10972291381533784,5.536190433847666,0.5860936833169975,-0.047826189001080696,0.9630480661374073,0.044535079266585564,4.542075388422235,-0.4229981043898459,1.6246199234372136,0.4973760257832683,0.5565914918730328,0.044535079266585564 | 3,044 |
Pcp ce pathway | 12 | 47 | 2.208745 | 0.027192 | P25786,Q14997,O00231,P28070,P28066,P61586,Q96CW1,P49721,Q99436,P28074,P20618,P60900 | Processes and pathways | Reactome Pathways | msigdb_reactome | 312,434,624,37,634,538,467,15,616,19,141,459 | 624,1057,1302,1485,1189,1068,1009,1495,1370,2597,960,141,312,962,1135,1694,634,37,1562,19,2011,2012,1374,910,15,1262,1443,2357,459,1150,538,1153,1507,1579,2017,1714,701,2606,918,1089,434,745,467,616,1531,2227,1054 | 0.4973760257832683,0.1971618513328632,0.07519205271216686,-0.016974318162148477,0.136309143857803,0.1971618513328632,0.22748833338166233,-0.016974318162148477,0.044535079266585564,-0.7102003873333911,0.2577478396839187,1.409322786798099,0.9058659736823905,0.2577478396839187,0.16676869031834232,-0.10972291381533784,0.4973760257832683,2.5790090186950474,-0.047826189001080696,3.0907836555787225,-0.26557808319442094,-0.26557808319442094,0.044535079266585564,0.28794007013935596,3.8164386931189918,0.10578350226676929,0.013812862961268305,-0.4863973353694144,0.6741739876103681,0.16676869031834232,0.5860936833169975,0.16676869031834232,-0.016974318162148477,-0.047826189001080696,-0.26557808319442094,-0.10972291381533784,0.43788134118310246,-0.7102003873333911,0.28794007013935596,0.1971618513328632,0.7033908346533452,0.4080301119164743,0.6741739876103681,0.5270188270799904,-0.016974318162148477,-0.3598443150443863,0.22748833338166233 | 3,044 |
Metabolism of steroids | 14 | 43 | 2.18574 | 0.028835 | Q14739,Q15392,O95487,P37268,Q86X55,O95772,P53992,P22059,O00763,Q14534,Q13085,Q16850,Q9UBM7,Q14849 | Processes and pathways | Reactome Pathways | msigdb_reactome | 35,2,280,329,406,78,361,398,85,303,118,26,95,63 | 85,1931,1244,280,78,2653,1557,1432,398,2574,2237,329,2578,2790,909,2321,361,739,2285,2839,118,2028,303,35,63,1456,2079,2,1091,573,2206,2031,26,1338,406,2146,761,2957,421,2821,2843,95,2857 | 1.7563813941642747,-0.23428085042851984,0.10578350226676929,0.9630480661374073,1.834429201344583,-0.7746811051942666,-0.047826189001080696,0.013812862961268305,0.7616075056451529,-0.6780488566603873,-0.3913904093021849,0.8771624436461539,-0.6780488566603873,-1.0022064159022008,0.28794007013935596,-0.4546671593010326,0.8195323729966623,0.4080301119164743,-0.4229981043898459,-1.1334880347917538,1.571307922760105,-0.26557808319442094,0.9344946467002561,2.602836514157032,2.039094910725132,0.013812862961268305,-0.29693790496602795,7.067902653089992,0.1971618513328632,0.5565914918730328,-0.3598443150443863,-0.26557808319442094,2.930653338734813,0.07519205271216686,0.7616075056451529,-0.328360064999706,0.4080301119164743,-1.566343719113424,0.7325354614920672,-1.0677332500167986,-1.1334880347917538,1.7039344627087378,-1.16645041336952 | 3,044 |
Regulation of hmox1 expression and activity | 13 | 45 | 2.157731 | 0.030949 | P67870,P25786,Q14997,O00231,P28070,Q05655,P28066,P49721,Q99436,P28074,P20618,P60900,P63208 | Processes and pathways | Reactome Pathways | msigdb_reactome | 662,312,434,624,37,490,634,15,616,19,141,459,315 | 624,1057,1302,1485,1189,1068,958,960,2503,141,312,962,1135,1694,634,37,1562,19,2011,2012,1374,910,15,1262,2357,459,1150,1153,1507,1579,315,662,490,2606,918,1586,1023,665,434,745,2150,616,1531,2227,1054 | 0.4973760257832683,0.1971618513328632,0.07519205271216686,-0.016974318162148477,0.136309143857803,0.1971618513328632,0.2577478396839187,0.2577478396839187,-0.61392455778647,1.409322786798099,0.9058659736823905,0.2577478396839187,0.16676869031834232,-0.10972291381533784,0.4973760257832683,2.5790090186950474,-0.047826189001080696,3.0907836555787225,-0.26557808319442094,-0.26557808319442094,0.044535079266585564,0.28794007013935596,3.8164386931189918,0.10578350226676929,-0.4863973353694144,0.6741739876103681,0.16676869031834232,0.16676869031834232,-0.016974318162148477,-0.047826189001080696,0.9058659736823905,0.4676634208377951,0.6448852783592486,-0.7102003873333911,0.28794007013935596,-0.047826189001080696,0.22748833338166233,0.4676634208377951,0.7033908346533452,0.4080301119164743,-0.328360064999706,0.5270188270799904,-0.016974318162148477,-0.3598443150443863,0.22748833338166233 | 3,044 |
Degradation of gli1 by the proteasome | 12 | 40 | 2.14138 | 0.032243 | P17612,P25786,Q14997,O00231,P28070,P60900,P49721,Q99436,P28074,P20618,Q96J02,P63208 | Processes and pathways | Reactome Pathways | msigdb_reactome | 160,312,434,624,37,459,15,616,19,141,554,315 | 624,1057,1302,1485,1189,1068,160,960,141,312,962,1135,1694,634,37,1562,19,2011,2012,1374,910,15,1262,2357,459,1150,1153,1507,1579,315,2606,918,1586,434,745,554,616,1531,2227,1054 | 0.4973760257832683,0.1971618513328632,0.07519205271216686,-0.016974318162148477,0.136309143857803,0.1971618513328632,1.3546589090705994,0.2577478396839187,1.409322786798099,0.9058659736823905,0.2577478396839187,0.16676869031834232,-0.10972291381533784,0.4973760257832683,2.5790090186950474,-0.047826189001080696,3.0907836555787225,-0.26557808319442094,-0.26557808319442094,0.044535079266585564,0.28794007013935596,3.8164386931189918,0.10578350226676929,-0.4863973353694144,0.6741739876103681,0.16676869031834232,0.16676869031834232,-0.016974318162148477,-0.047826189001080696,0.9058659736823905,-0.7102003873333911,0.28794007013935596,-0.047826189001080696,0.7033908346533452,0.4080301119164743,0.5860936833169975,0.5270188270799904,-0.016974318162148477,-0.3598443150443863,0.22748833338166233 | 3,044 |
Regulation of tp53 expression and degradation | 6 | 11 | 2.12579 | 0.033521 | P30153,P24941,P30154,P31751,P31749,P42345 | Processes and pathways | Reactome Pathways | msigdb_reactome | 530,507,508,49,341,246 | 1245,1612,1494,561,507,530,508,341,49,246,845 | 0.10578350226676929,-0.07874247734263141,-0.016974318162148477,0.5565914918730328,0.6155250604989404,0.5860936833169975,0.6155250604989404,0.8483844479781932,2.214330584420916,1.0482527573655716,0.3481214861512012 | 3,044 |
Proteasome core complex | 7 | 14 | 2.117916 | 0.034182 | P25786,P28070,P49721,Q99436,P20618,P28074,P60900 | Localization | GO Cellular component | msigdb_gocc | 312,37,15,616,141,19,459 | 1485,141,312,962,1135,1694,634,37,1562,19,910,15,459,616 | -0.016974318162148477,1.409322786798099,0.9058659736823905,0.2577478396839187,0.16676869031834232,-0.10972291381533784,0.4973760257832683,2.5790090186950474,-0.047826189001080696,3.0907836555787225,0.28794007013935596,3.8164386931189918,0.6741739876103681,0.5270188270799904 | 3,044 |
Proteasome, subunit alpha/beta [IPR001353] | 7 | 14 | 2.117916 | 0.034182 | P25786,P28070,P49721,Q99436,P20618,P28074,P60900 | Sequence | InterPro Family | interpro_family | 312,37,15,616,141,19,459 | 1485,141,312,962,1135,1694,634,37,1562,19,910,15,459,616 | -0.016974318162148477,1.409322786798099,0.9058659736823905,0.2577478396839187,0.16676869031834232,-0.10972291381533784,0.4973760257832683,2.5790090186950474,-0.047826189001080696,3.0907836555787225,0.28794007013935596,3.8164386931189918,0.6741739876103681,0.5270188270799904 | 3,044 |
Mapk6 mapk4 signaling | 12 | 48 | 2.115844 | 0.034358 | P17612,P25786,Q14997,O00231,P28070,P49721,P60953,Q99436,P28074,P20618,P60900,Q9HCE1 | Processes and pathways | Reactome Pathways | msigdb_reactome | 160,312,434,624,37,15,567,616,19,141,459,423 | 624,1057,1302,1485,723,1189,1068,2715,1494,160,960,141,1433,312,962,1135,1694,634,37,1562,19,2011,2012,1374,910,15,1262,2357,459,567,1150,1153,1507,1579,2017,2606,1512,918,434,745,2207,2945,616,1531,423,1671,2227,1054 | 0.4973760257832683,0.1971618513328632,0.07519205271216686,-0.016974318162148477,0.4080301119164743,0.136309143857803,0.1971618513328632,-0.8718430660882146,-0.016974318162148477,1.3546589090705994,0.2577478396839187,1.409322786798099,0.013812862961268305,0.9058659736823905,0.2577478396839187,0.16676869031834232,-0.10972291381533784,0.4973760257832683,2.5790090186950474,-0.047826189001080696,3.0907836555787225,-0.26557808319442094,-0.26557808319442094,0.044535079266585564,0.28794007013935596,3.8164386931189918,0.10578350226676929,-0.4863973353694144,0.6741739876103681,0.5565914918730328,0.16676869031834232,0.16676869031834232,-0.016974318162148477,-0.047826189001080696,-0.26557808319442094,-0.7102003873333911,-0.016974318162148477,0.28794007013935596,0.7033908346533452,0.4080301119164743,-0.3598443150443863,-1.4991446302853906,0.5270188270799904,-0.016974318162148477,0.7325354614920672,-0.07874247734263141,-0.3598443150443863,0.22748833338166233 | 3,044 |
Regulation of runx2 expression and activity | 12 | 41 | 2.113709 | 0.03454 | P25786,Q14997,O00231,P28070,P42224,P49721,Q13951,Q99436,P28074,P20618,P60900,P63208 | Processes and pathways | Reactome Pathways | msigdb_reactome | 312,434,624,37,602,15,142,616,19,141,459,315 | 624,1057,1302,1485,1189,1068,960,141,312,962,1135,1694,634,37,1562,19,2011,602,2012,1374,910,15,1262,2357,459,1150,1153,1507,1579,315,2606,918,1586,142,434,745,616,1531,2227,2346,1054 | 0.4973760257832683,0.1971618513328632,0.07519205271216686,-0.016974318162148477,0.136309143857803,0.1971618513328632,0.2577478396839187,1.409322786798099,0.9058659736823905,0.2577478396839187,0.16676869031834232,-0.10972291381533784,0.4973760257832683,2.5790090186950474,-0.047826189001080696,3.0907836555787225,-0.26557808319442094,0.5270188270799904,-0.26557808319442094,0.044535079266585564,0.28794007013935596,3.8164386931189918,0.10578350226676929,-0.4863973353694144,0.6741739876103681,0.16676869031834232,0.16676869031834232,-0.016974318162148477,-0.047826189001080696,0.9058659736823905,-0.7102003873333911,0.28794007013935596,-0.047826189001080696,1.409322786798099,0.7033908346533452,0.4080301119164743,0.5270188270799904,-0.016974318162148477,-0.3598443150443863,-0.4546671593010326,0.22748833338166233 | 3,044 |
Scf skp2 mediated degradation of p27 p21 | 12 | 40 | 2.09315 | 0.036336 | P25786,O00231,P28070,P24941,P20248,P11802,P49721,Q99436,P28074,P20618,P60900,P63208 | Processes and pathways | Reactome Pathways | msigdb_reactome | 312,624,37,507,561,327,15,616,19,141,459,315 | 624,1057,1302,1485,1189,1068,327,960,561,141,507,312,962,1135,1694,634,37,1562,19,2011,2012,1374,910,15,1262,2357,459,1150,1153,1507,1579,315,2606,918,1586,745,616,1531,2227,1054 | 0.4973760257832683,0.1971618513328632,0.07519205271216686,-0.016974318162148477,0.136309143857803,0.1971618513328632,0.8771624436461539,0.2577478396839187,0.5565914918730328,1.409322786798099,0.6155250604989404,0.9058659736823905,0.2577478396839187,0.16676869031834232,-0.10972291381533784,0.4973760257832683,2.5790090186950474,-0.047826189001080696,3.0907836555787225,-0.26557808319442094,-0.26557808319442094,0.044535079266585564,0.28794007013935596,3.8164386931189918,0.10578350226676929,-0.4863973353694144,0.6741739876103681,0.16676869031834232,0.16676869031834232,-0.016974318162148477,-0.047826189001080696,0.9058659736823905,-0.7102003873333911,0.28794007013935596,-0.047826189001080696,0.4080301119164743,0.5270188270799904,-0.016974318162148477,-0.3598443150443863,0.22748833338166233 | 3,044 |
Epigenetic regulator | 7 | 32 | 2.088067 | 0.036792 | Q9H7B4,Q8NB78,Q9NRG4,Q9BXF3,Q9NPI1,Q9H8M2,Q16637 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 0,3,6,277,54,221,292 | 557,1884,504,1758,658,1561,281,2719,2538,2639,1782,1784,1273,1584,292,1977,1657,406,3,614,2401,1596,888,2832,2446,555,277,0,221,2593,54,6 | 0.5565914918730328,-0.20304645994480822,0.6155250604989404,-0.14076723184203568,0.4676634208377951,-0.047826189001080696,0.9630480661374073,-0.8718430660882146,-0.645956839059224,-0.7424112098929048,-0.14076723184203568,-0.14076723184203568,0.10578350226676929,-0.047826189001080696,0.9630480661374073,-0.23428085042851984,-0.07874247734263141,0.7616075056451529,6.71929476880315,0.5270188270799904,-0.5181883962325351,-0.047826189001080696,0.3180647212684595,-1.1005822480638625,-0.550040107796456,0.5860936833169975,0.9915258301454644,7.89617898773074,1.132765369430272,-0.6780488566603873,2.164611651394882,5.250604250509582 | 3,044 |
Secondary alcohol metabolic process | 11 | 43 | 2.062589 | 0.039152 | Q15392,P98155,Q14739,P48735,P50213,Q06520,O75874,Q14534,Q16850,Q9UBM7,Q14849 | Processes and pathways | GO Biological process | msigdb_gobp | 2,132,35,135,139,16,203,303,26,95,63 | 1303,1883,203,2806,1887,2771,2653,2927,2911,1890,1557,1891,2237,1257,1955,329,603,2790,135,139,1709,1504,2722,132,1844,2839,16,2028,303,35,63,402,2079,2,2206,2031,26,495,2042,2968,2843,95,2306 | 0.07519205271216686,-0.20304645994480822,1.160780451278084,-1.034941239199341,-0.20304645994480822,-0.9695289821825922,-0.7746811051942666,-1.432163677429818,-1.36540230172939,-0.20304645994480822,-0.047826189001080696,-0.20304645994480822,-0.3913904093021849,0.10578350226676929,-0.23428085042851984,0.8771624436461539,0.5270188270799904,-1.0022064159022008,1.4636550239775168,1.4365306156375974,-0.10972291381533784,-0.016974318162148477,-0.8718430660882146,1.4906954915337542,-0.17187516759377872,-1.1334880347917538,3.514085926832498,-0.26557808319442094,0.9344946467002561,2.602836514157032,2.039094910725132,0.7616075056451529,-0.29693790496602795,7.067902653089992,-0.3598443150443863,-0.26557808319442094,2.930653338734813,0.6448852783592486,-0.26557808319442094,-1.6337595261138573,-1.1334880347917538,1.7039344627087378,-0.4229981043898459 | 3,044 |
Disproportionate short limb short stature | 6 | 20 | 2.054197 | 0.039957 | Q15392,Q14739,Q7RTS9,Q32P28,Q7LGA3,Q9UBM7 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 2,35,10,47,152,95 | 813,1753,2462,1129,1889,2534,246,1571,2914,2291,35,2,47,2141,152,10,841,498,443,95 | 0.3481214861512012,-0.14076723184203568,-0.5819522382011225,0.16676869031834232,-0.20304645994480822,-0.645956839059224,1.0482527573655716,-0.047826189001080696,-1.36540230172939,-0.4229981043898459,2.602836514157032,7.067902653089992,2.2637799306174515,-0.328360064999706,1.382032049767132,4.542075388422235,0.3481214861512012,0.6448852783592486,0.7033908346533452,1.7039344627087378 | 3,044 |
Limb undergrowth | 8 | 47 | 2.053532 | 0.040021 | P17612,Q15392,Q14739,P48735,Q7RTS9,O75874,Q9UBM7,P42345 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 160,2,35,135,10,203,95,246 | 813,1057,2001,1753,2349,1364,2694,1758,2462,1129,203,1769,1889,160,2423,2534,562,533,2281,2472,2390,246,1571,135,782,2508,2017,1085,2914,286,2510,35,2,1974,2141,2829,10,2992,2514,2299,443,1292,1925,95,901,2412,2497 | 0.3481214861512012,0.1971618513328632,-0.26557808319442094,-0.14076723184203568,-0.4863973353694144,0.044535079266585564,-0.8393972474681705,-0.14076723184203568,-0.5819522382011225,0.16676869031834232,1.160780451278084,-0.14076723184203568,-0.20304645994480822,1.3546589090705994,-0.550040107796456,-0.645956839059224,0.5565914918730328,0.5860936833169975,-0.4229981043898459,-0.5819522382011225,-0.5181883962325351,1.0482527573655716,-0.047826189001080696,1.4636550239775168,0.3781100543642303,-0.61392455778647,-0.26557808319442094,0.1971618513328632,-1.36540230172939,0.9630480661374073,-0.61392455778647,2.602836514157032,7.067902653089992,-0.23428085042851984,-0.328360064999706,-1.1005822480638625,4.542075388422235,-1.8714015644708346,-0.61392455778647,-0.4229981043898459,0.7033908346533452,0.10578350226676929,-0.20304645994480822,1.7039344627087378,0.3180647212684595,-0.5181883962325351,-0.5819522382011225 | 3,044 |
Peripheral axonal degeneration | 14 | 62 | 2.040502 | 0.0413 | Q15813,Q15067,O95831,P07384,P41440,O15270,P34897,Q6DKK2,Q6DD88,Q15046,Q15526,P22626,P39210,P03886 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 291,289,5,413,39,411,138,265,43,288,403,399,24,58 | 1061,411,629,950,428,691,2271,5,956,2382,58,2715,1195,413,2967,2234,1072,1197,1313,1949,399,1078,138,822,24,601,39,2244,2130,1502,1574,1777,1505,1839,1265,1332,2433,1217,288,289,403,291,2208,43,265,1225,577,1731,2332,1526,1527,1736,2997,1400,1991,2100,1926,1182,1117,1748,1997,1122 | 0.1971618513328632,0.7325354614920672,0.4973760257832683,0.2577478396839187,0.7033908346533452,0.43788134118310246,-0.4229981043898459,5.536190433847666,0.2577478396839187,-0.5181883962325351,2.114617131220128,-0.8718430660882146,0.136309143857803,0.7325354614920672,-1.6337595261138573,-0.3913904093021849,0.1971618513328632,0.136309143857803,0.07519205271216686,-0.23428085042851984,0.7616075056451529,0.1971618513328632,1.4365306156375974,0.3481214861512012,2.9995737889502343,0.5270188270799904,2.386261231789582,-0.3913904093021849,-0.328360064999706,-0.016974318162148477,-0.047826189001080696,-0.14076723184203568,-0.016974318162148477,-0.17187516759377872,0.10578350226676929,0.07519205271216686,-0.550040107796456,0.136309143857803,0.9630480661374073,0.9630480661374073,0.7616075056451529,0.9630480661374073,-0.3598443150443863,2.337461049336215,1.0199275314764034,0.136309143857803,0.5565914918730328,-0.10972291381533784,-0.4546671593010326,-0.016974318162148477,-0.016974318162148477,-0.10972291381533784,-2.0083590588041704,0.044535079266585564,-0.23428085042851984,-0.29693790496602795,-0.20304645994480822,0.16676869031834232,0.1971618513328632,-0.10972291381533784,-0.23428085042851984,0.1971618513328632 | 3,044 |
G1 s dna damage checkpoints | 11 | 41 | 2.031728 | 0.042181 | P25786,Q14997,O00231,P28070,P24941,P20248,P49721,Q99436,P28074,P20618,P60900 | Processes and pathways | Reactome Pathways | msigdb_reactome | 312,434,624,37,507,561,15,616,19,141,459 | 624,1057,1302,1545,1485,1189,1068,1245,1612,960,561,141,507,312,962,1135,1694,634,37,1562,19,2011,2012,1374,910,15,1262,2357,459,1150,1153,1507,1579,2606,918,434,745,616,1531,2227,1054 | 0.4973760257832683,0.1971618513328632,0.07519205271216686,-0.047826189001080696,-0.016974318162148477,0.136309143857803,0.1971618513328632,0.10578350226676929,-0.07874247734263141,0.2577478396839187,0.5565914918730328,1.409322786798099,0.6155250604989404,0.9058659736823905,0.2577478396839187,0.16676869031834232,-0.10972291381533784,0.4973760257832683,2.5790090186950474,-0.047826189001080696,3.0907836555787225,-0.26557808319442094,-0.26557808319442094,0.044535079266585564,0.28794007013935596,3.8164386931189918,0.10578350226676929,-0.4863973353694144,0.6741739876103681,0.16676869031834232,0.16676869031834232,-0.016974318162148477,-0.047826189001080696,-0.7102003873333911,0.28794007013935596,0.7033908346533452,0.4080301119164743,0.5270188270799904,-0.016974318162148477,-0.3598443150443863,0.22748833338166233 | 3,044 |
Proteasome complex | 11 | 44 | 2.007505 | 0.044696 | P25786,Q14997,O00231,P28070,Q15386,Q5VYK3,P49721,Q99436,P28074,P20618,P60900 | Localization | GO Cellular component | msigdb_gocc | 312,434,624,37,75,549,15,616,19,141,459 | 624,1057,1302,1485,1189,688,1068,2715,960,141,312,962,1135,1694,634,37,1562,19,2011,2012,1374,910,15,1262,1575,1209,2357,1839,459,1150,1153,1507,1579,2606,918,434,745,75,549,616,1531,2227,1054,2057 | 0.4973760257832683,0.1971618513328632,0.07519205271216686,-0.016974318162148477,0.136309143857803,0.43788134118310246,0.1971618513328632,-0.8718430660882146,0.2577478396839187,1.409322786798099,0.9058659736823905,0.2577478396839187,0.16676869031834232,-0.10972291381533784,0.4973760257832683,2.5790090186950474,-0.047826189001080696,3.0907836555787225,-0.26557808319442094,-0.26557808319442094,0.044535079266585564,0.28794007013935596,3.8164386931189918,0.10578350226676929,-0.047826189001080696,0.136309143857803,-0.4863973353694144,-0.17187516759377872,0.6741739876103681,0.16676869031834232,0.16676869031834232,-0.016974318162148477,-0.047826189001080696,-0.7102003873333911,0.28794007013935596,0.7033908346533452,0.4080301119164743,1.860283266571758,0.5860936833169975,0.5270188270799904,-0.016974318162148477,-0.3598443150443863,0.22748833338166233,-0.26557808319442094 | 3,044 |
Cdt1 association with the cdc6 orc origin complex | 11 | 39 | 2.002461 | 0.045235 | P25786,Q14997,O00231,P28070,P49721,Q99436,P28074,P20618,O43913,Q9UBD5,P60900 | Processes and pathways | Reactome Pathways | msigdb_reactome | 312,434,624,37,15,616,19,141,454,115,459 | 624,1057,1302,1485,1189,454,1068,960,141,312,962,1135,1694,634,37,1562,19,2011,2012,1374,910,15,1262,2357,459,1150,1153,1507,1579,2606,918,434,745,616,1531,115,2227,1054,1360 | 0.4973760257832683,0.1971618513328632,0.07519205271216686,-0.016974318162148477,0.136309143857803,0.6741739876103681,0.1971618513328632,0.2577478396839187,1.409322786798099,0.9058659736823905,0.2577478396839187,0.16676869031834232,-0.10972291381533784,0.4973760257832683,2.5790090186950474,-0.047826189001080696,3.0907836555787225,-0.26557808319442094,-0.26557808319442094,0.044535079266585564,0.28794007013935596,3.8164386931189918,0.10578350226676929,-0.4863973353694144,0.6741739876103681,0.16676869031834232,0.16676869031834232,-0.016974318162148477,-0.047826189001080696,-0.7102003873333911,0.28794007013935596,0.7033908346533452,0.4080301119164743,0.5270188270799904,-0.016974318162148477,1.5980072576548476,-0.3598443150443863,0.22748833338166233,0.07519205271216686 | 3,044 |
Downstream signaling events of b cell receptor bcr | 12 | 43 | 1.997698 | 0.045749 | P25786,Q14997,O00231,P28070,P49721,Q99436,P28074,P20618,P62942,P60900,Q08209,P63208 | Processes and pathways | Reactome Pathways | msigdb_reactome | 312,434,624,37,15,616,19,141,488,459,542,315 | 624,1057,1302,1485,1060,2001,1189,1068,2750,960,141,312,962,1135,1694,634,37,1562,19,2011,2012,1374,910,15,1262,2357,459,1150,1153,1507,1579,488,315,2606,542,918,1586,434,745,616,1531,2227,1054 | 0.4973760257832683,0.1971618513328632,0.07519205271216686,-0.016974318162148477,0.1971618513328632,-0.26557808319442094,0.136309143857803,0.1971618513328632,-0.9369091418892902,0.2577478396839187,1.409322786798099,0.9058659736823905,0.2577478396839187,0.16676869031834232,-0.10972291381533784,0.4973760257832683,2.5790090186950474,-0.047826189001080696,3.0907836555787225,-0.26557808319442094,-0.26557808319442094,0.044535079266585564,0.28794007013935596,3.8164386931189918,0.10578350226676929,-0.4863973353694144,0.6741739876103681,0.16676869031834232,0.16676869031834232,-0.016974318162148477,-0.047826189001080696,0.6448852783592486,0.9058659736823905,-0.7102003873333911,0.5860936833169975,0.28794007013935596,-0.047826189001080696,0.7033908346533452,0.4080301119164743,0.5270188270799904,-0.016974318162148477,-0.3598443150443863,0.22748833338166233 | 3,044 |
Hyperthyroidism | 6 | 10 | 1.99738 | 0.045784 | O14802,Q06787,P53992,Q92890,Q9BUK6,P31749 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 242,663,361,674,185,341 | 242,1197,730,341,361,1445,663,1287,674,185 | 1.0482527573655716,0.136309143857803,0.4080301119164743,0.8483844479781932,0.8195323729966623,0.013812862961268305,0.4676634208377951,0.10578350226676929,0.4676634208377951,1.244352138092191 | 3,044 |
Mitotic g1 phase and g1 s transition | 24 | 74 | 1.995403 | 0.045999 | P63151,O00231,P33993,P24941,P30154,P49721,P28074,P20618,Q07864,P28070,P30153,Q14181,P31751,P63208,P25786,P20248,P11802,Q99436,O43913,P60900,P31749,P00374,Q9UBD5,Q9NRF9 | Processes and pathways | Reactome Pathways | msigdb_reactome | 638,624,509,507,508,15,19,141,286,37,530,166,49,315,312,561,327,616,454,459,341,596,115,254 | 624,1057,1302,1485,1189,454,2873,1068,596,1010,1494,1822,2752,2120,327,1619,1201,1202,960,561,141,507,1204,312,962,1135,1694,821,634,37,1562,19,530,508,908,341,49,733,1699,509,2011,2012,1374,1376,2013,910,15,911,1262,2357,459,1150,1153,1507,1579,638,315,2606,286,918,1584,1586,166,1646,745,1169,616,1531,2341,254,115,2227,1054,1360 | 0.4973760257832683,0.1971618513328632,0.07519205271216686,-0.016974318162148477,0.136309143857803,0.6741739876103681,-1.2325441671985713,0.1971618513328632,0.5270188270799904,0.22748833338166233,-0.016974318162148477,-0.17187516759377872,-0.9369091418892902,-0.328360064999706,0.8771624436461539,-0.07874247734263141,0.136309143857803,0.136309143857803,0.2577478396839187,0.5565914918730328,1.409322786798099,0.6155250604989404,0.136309143857803,0.9058659736823905,0.2577478396839187,0.16676869031834232,-0.10972291381533784,0.3481214861512012,0.4973760257832683,2.5790090186950474,-0.047826189001080696,3.0907836555787225,0.5860936833169975,0.6155250604989404,0.28794007013935596,0.8483844479781932,2.214330584420916,0.4080301119164743,-0.10972291381533784,0.6155250604989404,-0.26557808319442094,-0.26557808319442094,0.044535079266585564,0.044535079266585564,-0.26557808319442094,0.28794007013935596,3.8164386931189918,0.28794007013935596,0.10578350226676929,-0.4863973353694144,0.6741739876103681,0.16676869031834232,0.16676869031834232,-0.016974318162148477,-0.047826189001080696,0.4973760257832683,0.9058659736823905,-0.7102003873333911,0.9630480661374073,0.28794007013935596,-0.047826189001080696,-0.047826189001080696,1.3272038616395643,-0.07874247734263141,0.4080301119164743,0.16676869031834232,0.5270188270799904,-0.016974318162148477,-0.4546671593010326,1.0482527573655716,1.5980072576548476,-0.3598443150443863,0.22748833338166233,0.07519205271216686 | 3,044 |
Enlarged thorax | 7 | 19 | 1.981914 | 0.047489 | P17612,Q14739,P22681,Q7RTS9,Q99575,Q32P28,O75844 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 160,35,261,10,108,47,213 | 213,2382,2734,1823,160,261,1317,2579,1377,1087,1450,35,47,351,2443,10,2589,1799,108 | 1.132765369430272,-0.5181883962325351,-0.9043471006881587,-0.17187516759377872,1.3546589090705994,1.0199275314764034,0.07519205271216686,-0.6780488566603873,0.044535079266585564,0.1971618513328632,0.013812862961268305,2.602836514157032,2.2637799306174515,0.8483844479781932,-0.550040107796456,4.542075388422235,-0.6780488566603873,-0.14076723184203568,1.6246199234372136 | 3,044 |
Regulation of pten stability and activity | 12 | 41 | 1.978698 | 0.04785 | P25786,Q14997,O00231,P28070,P28066,P49721,P31751,P28074,P20618,Q99436,P60900,P31749 | Processes and pathways | Reactome Pathways | msigdb_reactome | 312,434,624,37,634,15,49,19,141,616,459,341 | 624,1057,1302,1485,1189,1068,960,2503,141,312,962,1135,1694,634,37,1562,19,341,49,2011,2012,1374,910,15,1262,2357,459,1150,1153,1507,1579,662,2606,918,434,745,616,1531,2227,2346,1054 | 0.4973760257832683,0.1971618513328632,0.07519205271216686,-0.016974318162148477,0.136309143857803,0.1971618513328632,0.2577478396839187,-0.61392455778647,1.409322786798099,0.9058659736823905,0.2577478396839187,0.16676869031834232,-0.10972291381533784,0.4973760257832683,2.5790090186950474,-0.047826189001080696,3.0907836555787225,0.8483844479781932,2.214330584420916,-0.26557808319442094,-0.26557808319442094,0.044535079266585564,0.28794007013935596,3.8164386931189918,0.10578350226676929,-0.4863973353694144,0.6741739876103681,0.16676869031834232,0.16676869031834232,-0.016974318162148477,-0.047826189001080696,0.4676634208377951,-0.7102003873333911,0.28794007013935596,0.7033908346533452,0.4080301119164743,0.5270188270799904,-0.016974318162148477,-0.3598443150443863,-0.4546671593010326,0.22748833338166233 | 3,044 |
Intrinsic component of mitochondrial membrane | 18 | 50 | 4.503852 | 0.000007 | Q9GZY8,Q99595,O60830,Q9UG56,Q13505,Q9NX63,Q9H9P8,O14925,Q9Y2R0,Q9BPX6,Q5HYI7,O75880,Q8N8Q8,Q15388,P57105,O75431,Q9Y4W6,Q8IWA4 | Localization | GO Cellular component | msigdb_gocc | 396,1,0,290,36,195,65,264,48,471,364,275,341,465,122,88,382,450 | 264,1575,0,88,275,1336,2157,568,1309,604,2356,1768,1675,122,2126,36,980,465,1378,833,834,938,364,697,1592,1421,450,984,1780,341,1085,1268,1171,1,471,693,1229,396,945,1698,65,1433,1151,484,195,290,1569,48,382,1858 | 1.3707265386892524,-0.057841396040278596,5.073603072328636,2.314221925162671,1.355195299175073,0.08072799489487778,-0.37575235994719464,0.7831506553954769,0.09793572799284321,0.7342899684920763,-0.48369809024111093,-0.16284975656285822,-0.1102279128477972,2.0070251955300082,-0.3578598430231122,2.9781043788454484,0.33627924845100304,0.9285979925872347,0.06349529754497407,0.47039145099938634,0.47039145099938634,0.3699463810201887,1.1199563718210412,0.6195286455637697,-0.057841396040278596,0.04623753210788857,0.9606924188585974,0.33627924845100304,-0.16284975656285822,1.1673498693322624,0.2516987221968761,0.13227671324131024,0.20066360371072753,4.964986919891834,0.9285979925872347,0.6359884017355526,0.16651906993514767,1.0723863455217324,0.3699463810201887,-0.1102279128477972,2.6147267152556526,0.04623753210788857,0.21769943580617096,0.9125200992112816,1.6623656284021715,1.3084896317780137,-0.04043100103272851,2.7975768714129026,1.088262751441023,-0.19806322542449376 | 3,381 |
Protein targeting to mitochondrion | 15 | 46 | 4.109903 | 0.00004 | O60830,Q99595,Q8N4H5,O43464,Q9NS69,Q5JRX3,Q99797,O14925,P55786,Q9Y5J7,Q9Y5J9,Q9Y5L4,O00170,O60220,O14737 | Processes and pathways | GO Biological process | msigdb_gobp | 0,1,33,162,5,197,7,264,113,115,84,310,279,121,91 | 738,279,91,264,162,1255,121,0,1181,1336,602,927,568,1466,2757,2227,315,2604,788,1107,113,2125,1001,1415,465,1718,959,834,197,2094,33,1268,1,7,1430,396,1045,5,3336,749,642,1731,1858,115,84,310 | 0.5534689593446168,1.3396454442052559,2.299748594818239,1.3707265386892524,1.7982920845921333,0.13227671324131024,2.0070251955300082,5.073603072328636,0.18360351475980163,0.08072799489487778,0.7342899684920763,0.3699463810201887,0.7831506553954769,0.011646378050987276,-0.7396367924488996,-0.41162126510560293,1.23026980961867,-0.6292368396202702,0.5036901138602248,0.2347111094017979,2.1248688461959304,-0.3578598430231122,0.3194104967216977,0.04623753210788857,0.9285979925872347,-0.12774223079298147,0.3531245121268438,0.47039145099938634,1.647176397021248,-0.3399951175936339,3.046937180331755,0.13227671324131024,4.964986919891834,4.144909340259825,0.04623753210788857,1.0723863455217324,0.285602152936856,4.32249087085326,-1.910089858268988,0.5534689593446168,0.7016092735780922,-0.12774223079298147,-0.19806322542449376,2.09550357539617,2.3575511001107285,1.2459517836247969 | 3,381 |
Protein localization to mitochondrion | 22 | 61 | 4.030347 | 0.000056 | Q9GZY8,Q99595,O60830,Q9NS69,Q99797,P52789,O14925,P31749,O00170,Q8N4H5,O43464,P0DP25,Q9Y6C9,Q9Y5L4,P30536,Q5JRX3,Q9Y5J9,Q8N8Q8,O14737,P55786,Q9Y5J7,O60220 | Processes and pathways | GO Biological process | msigdb_gobp | 396,1,0,5,7,385,264,269,279,33,162,294,425,310,315,197,84,341,91,113,115,121 | 738,279,2932,924,91,264,162,1255,121,0,1181,1336,602,927,568,1466,294,2757,2190,2226,2227,2676,315,1281,269,2604,788,1107,385,113,2125,915,1001,1415,980,465,1718,959,834,197,2094,33,341,1268,1,7,1430,396,1045,5,2372,3336,749,642,2248,1731,1858,115,84,310,425 | 0.5534689593446168,1.3396454442052559,-0.8698314423424568,0.3699463810201887,2.299748594818239,1.3707265386892524,1.7982920845921333,0.13227671324131024,2.0070251955300082,5.073603072328636,0.18360351475980163,0.08072799489487778,0.7342899684920763,0.3699463810201887,0.7831506553954769,0.011646378050987276,1.292883545349269,-0.7396367924488996,-0.39367279234365044,-0.41162126510560293,-0.41162126510560293,-0.6843010420962635,1.23026980961867,0.11511859996624757,1.3707265386892524,-0.6292368396202702,0.5036901138602248,0.2347111094017979,1.0723863455217324,2.1248688461959304,-0.3578598430231122,0.3867449477923637,0.3194104967216977,0.04623753210788857,0.33627924845100304,0.9285979925872347,-0.12774223079298147,0.3531245121268438,0.47039145099938634,1.647176397021248,-0.3399951175936339,3.046937180331755,1.1673498693322624,0.13227671324131024,4.964986919891834,4.144909340259825,0.04623753210788857,1.0723863455217324,0.285602152936856,4.32249087085326,-0.48369809024111093,-1.910089858268988,0.5534689593446168,0.7016092735780922,-0.41162126510560293,-0.12774223079298147,-0.19806322542449376,2.09550357539617,2.3575511001107285,1.2459517836247969,1.0086817664528895 | 3,381 |
Mitochondrial transmembrane transport | 17 | 53 | 3.828347 | 0.000129 | O60830,Q99595,Q9BQT8,O95202,P21796,Q9H2D1,O14925,O43772,O75964,P56134,Q9BPX6,Q9Y4W6,P00846,Q15388,P06576,Q8IYU8,Q9BSK2 | Processes and pathways | GO Biological process | msigdb_gobp | 0,1,262,131,199,103,264,296,46,304,471,382,54,465,371,451,94 | 264,1255,296,0,1235,1181,898,1576,46,1336,131,2157,927,568,54,2646,371,2757,1309,1542,199,929,914,756,1103,3199,1675,2286,304,865,2126,465,3185,959,1592,451,1085,2175,1171,1,471,262,94,103,1271,1698,1045,2769,484,1331,683,382,2349 | 1.3707265386892524,0.13227671324131024,1.2772585855164569,5.073603072328636,0.14941016954971006,0.18360351475980163,0.40352030450058385,-0.057841396040278596,2.7975768714129026,0.08072799489487778,1.9328488984240189,-0.37575235994719464,0.3699463810201887,0.7831506553954769,2.727529421964283,-0.6659163242058336,1.1041194035027075,-0.7396367924488996,0.09793572799284321,-0.04043100103272851,1.6319696996489776,0.3699463810201887,0.3867449477923637,0.5368984476537072,0.2347111094017979,-1.1925822871771383,-0.1102279128477972,-0.44760283593211736,1.2616146868698537,0.4370017529662837,-0.3578598430231122,0.9285979925872347,-1.154111245668569,0.3531245121268438,-0.057841396040278596,0.9606924188585974,0.2516987221968761,-0.37575235994719464,0.20066360371072753,4.964986919891834,0.9285979925872347,1.3862392263267762,2.2707562529589636,2.2271528467595973,0.13227671324131024,-0.1102279128477972,0.285602152936856,-0.7396367924488996,0.9125200992112816,0.09793572799284321,0.6524262597868276,1.088262751441023,-0.4656361884453895 | 3,381 |
Mitochondrial protein import | 14 | 36 | 3.725965 | 0.000195 | O60830,Q99595,Q8N4H5,Q9NX63,Q13505,Q9NS69,Q5JRX3,P21796,O14925,Q9Y5J7,Q9Y5J9,Q9Y5L4,O75431,O60220 | Processes and pathways | Reactome Pathways | msigdb_reactome | 0,1,33,195,36,5,197,199,264,115,84,310,88,121 | 264,1255,121,0,3290,88,1181,898,1336,568,371,1050,2757,1309,1542,199,756,2356,2285,1001,36,465,959,197,33,1,3175,1045,5,195,1331,2248,1858,115,84,310 | 1.3707265386892524,0.13227671324131024,2.0070251955300082,5.073603072328636,-1.4658172577816313,2.314221925162671,0.18360351475980163,0.40352030450058385,0.08072799489487778,0.7831506553954769,1.1041194035027075,0.26866237124034603,-0.7396367924488996,0.09793572799284321,-0.04043100103272851,1.6319696996489776,0.5368984476537072,-0.48369809024111093,-0.44760283593211736,0.3194104967216977,2.9781043788454484,0.9285979925872347,0.3531245121268438,1.647176397021248,3.046937180331755,4.964986919891834,-1.1349269369210717,0.285602152936856,4.32249087085326,1.6623656284021715,0.09793572799284321,-0.41162126510560293,-0.19806322542449376,2.09550357539617,2.3575511001107285,1.2459517836247969 | 3,381 |
Intrinsic component of mitochondrial inner membrane | 12 | 34 | 3.708895 | 0.000208 | O60830,Q99595,Q9UG56,Q9NX63,Q13505,Q9H9P8,O14925,Q9Y2R0,Q5HYI7,O75880,Q8N8Q8,O75431 | Localization | GO Cellular component | msigdb_gocc | 0,1,290,195,36,65,264,48,364,275,341,88 | 264,1575,0,88,275,2157,604,2356,1768,2126,36,980,1378,833,834,938,364,697,1592,1421,341,1085,1171,1,945,1698,65,1151,484,195,290,48,382,1858 | 1.3707265386892524,-0.057841396040278596,5.073603072328636,2.314221925162671,1.355195299175073,-0.37575235994719464,0.7342899684920763,-0.48369809024111093,-0.16284975656285822,-0.3578598430231122,2.9781043788454484,0.33627924845100304,0.06349529754497407,0.47039145099938634,0.47039145099938634,0.3699463810201887,1.1199563718210412,0.6195286455637697,-0.057841396040278596,0.04623753210788857,1.1673498693322624,0.2516987221968761,0.20066360371072753,4.964986919891834,0.3699463810201887,-0.1102279128477972,2.6147267152556526,0.21769943580617096,0.9125200992112816,1.6623656284021715,1.3084896317780137,2.7975768714129026,1.088262751441023,-0.19806322542449376 | 3,381 |
Translocation | 17 | 50 | 3.703872 | 0.000212 | O60830,Q99595,Q8NFH4,Q9NS69,Q7Z3B4,O14925,Q15629,Q9BW27,O75381,Q9Y5J7,Q9Y5J9,P41208,Q9Y5L4,O60220,Q8N1F7,Q9BTX1,Q8TD16 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 0,1,327,5,186,264,72,459,486,115,84,116,310,121,548,483,188 | 3044,264,1027,1255,121,0,486,2013,570,1963,1493,116,3125,1282,1842,1241,3325,3146,2123,930,886,72,959,1652,1589,186,548,2653,327,1533,188,2059,1447,2689,2267,2179,1427,1428,1,483,1565,459,2699,5,1568,1856,2719,115,84,310 | -0.9637739539367629,1.3707265386892524,0.285602152936856,0.13227671324131024,2.0070251955300082,5.073603072328636,0.8964216526892619,-0.3043485498283727,0.7831506553954769,-0.2688116827850815,-0.0056872218402178,2.080797152869033,-1.0585271123335283,0.11511859996624757,-0.19806322542449376,0.14941016954971006,-1.7870173720445042,-1.0966598820951519,-0.3578598430231122,0.3699463810201887,0.4202725426034364,2.4867317377474243,0.3531245121268438,-0.09273974181183568,-0.057841396040278596,1.7229490341498392,0.8318208221873443,-0.6659163242058336,1.1988483827647884,-0.02304631237539939,1.707829097433171,-0.3221580605870234,0.028954594033709185,-0.6843010420962635,-0.4295979040509883,-0.37575235994719464,0.04623753210788857,0.04623753210788857,4.964986919891834,0.9125200992112816,-0.04043100103272851,0.944655407668733,-0.6843010420962635,4.32249087085326,-0.04043100103272851,-0.19806322542449376,-0.7027159312432755,2.09550357539617,2.3575511001107285,1.2459517836247969 | 3,381 |
Mitochondrial transport | 27 | 84 | 3.666785 | 0.000246 | O60830,Q99595,Q9GZY8,Q9NS69,Q99797,O14925,P52789,O00170,Q8N4H5,O43464,O75964,O43772,P56134,Q9UBX3,P00846,Q9Y5L4,P45880,P30536,Q5JRX3,Q9Y5J9,Q8N8Q8,O75431,O14737,P06576,P55786,Q9Y5J7,O60220 | Processes and pathways | GO Biological process | msigdb_gobp | 0,1,396,5,7,264,385,279,33,162,46,296,304,178,54,310,184,315,197,84,341,88,91,371,113,115,121 | 738,279,91,264,162,1255,296,121,0,88,1181,1576,46,1336,602,927,568,54,1540,2646,371,1466,2535,2757,1309,2227,929,914,756,3236,2676,315,2604,1103,2761,184,3199,788,954,1675,1107,385,113,304,865,2125,915,1001,1415,619,980,465,1718,959,834,197,1687,2094,984,1780,33,341,1268,403,1198,1,7,1430,396,1045,1433,5,3336,749,178,642,1331,683,2248,1731,1858,115,84,310 | 0.5534689593446168,1.3396454442052559,2.299748594818239,1.3707265386892524,1.7982920845921333,0.13227671324131024,1.2772585855164569,2.0070251955300082,5.073603072328636,2.314221925162671,0.18360351475980163,-0.057841396040278596,2.7975768714129026,0.08072799489487778,0.7342899684920763,0.3699463810201887,0.7831506553954769,2.727529421964283,-0.04043100103272851,-0.6659163242058336,1.1041194035027075,0.011646378050987276,-0.5926763630965615,-0.7396367924488996,0.09793572799284321,-0.41162126510560293,0.3699463810201887,0.3867449477923637,0.5368984476537072,-1.3088274981671097,-0.6843010420962635,1.23026980961867,-0.6292368396202702,0.2347111094017979,-0.7396367924488996,1.7229490341498392,-1.1925822871771383,0.5036901138602248,0.3531245121268438,-0.1102279128477972,0.2347111094017979,1.0723863455217324,2.1248688461959304,1.2616146868698537,0.4370017529662837,-0.3578598430231122,0.3867449477923637,0.3194104967216977,0.04623753210788857,0.7179603649304444,0.33627924845100304,0.9285979925872347,-0.12774223079298147,0.3531245121268438,0.47039145099938634,1.647176397021248,-0.1102279128477972,-0.3399951175936339,0.33627924845100304,-0.16284975656285822,3.046937180331755,1.1673498693322624,0.13227671324131024,1.0564901152174682,0.18360351475980163,4.964986919891834,4.144909340259825,0.04623753210788857,1.0723863455217324,0.285602152936856,0.04623753210788857,4.32249087085326,-1.910089858268988,0.5534689593446168,1.7531374146957515,0.7016092735780922,0.09793572799284321,0.6524262597868276,-0.41162126510560293,-0.12774223079298147,-0.19806322542449376,2.09550357539617,2.3575511001107285,1.2459517836247969 | 3,381 |
Mitochondrial respiratory chain complex assembly | 15 | 44 | 3.634968 | 0.000278 | O43674,Q86Y39,Q6DKK2,Q9Y6M9,Q96CU9,Q69YU5,Q9Y2R0,O43676,O75880,Q8N8Q8,P03886,Q9BSK2,Q16718,P56556,Q9H061 | Processes and pathways | GO Biological process | msigdb_gobp | 287,350,105,436,14,15,48,17,275,341,247,94,154,125,30 | 287,17,1575,2562,1760,1539,825,275,1210,646,1360,927,1256,247,3305,1470,1677,125,1242,980,154,2458,15,105,595,350,468,341,1476,14,654,944,94,1949,30,1728,1483,1173,1891,3336,2248,48,1858,436 | 1.3240769098404388,3.5198547952428183,-0.057841396040278596,-0.610941794333371,-0.16284975656285822,-0.04043100103272851,0.47039145099938634,1.355195299175073,0.16651906993514767,0.6852366133893191,0.06349529754497407,0.3699463810201887,0.13227671324131024,1.417209198502823,-1.5451951225647298,0.011646378050987276,-0.1102279128477972,1.9922224857685245,0.14941016954971006,0.33627924845100304,1.8283105702783014,-0.5380563923449663,3.5994225347475823,2.1834104512228016,0.7505981648073553,1.151571535639279,0.9285979925872347,1.1673498693322624,0.011646378050987276,3.665405898737808,0.6852366133893191,0.3699463810201887,2.2707562529589636,-0.25108408655359427,3.156391655179004,-0.12774223079298147,0.011646378050987276,0.20066360371072753,-0.21570997527597668,-1.910089858268988,-0.41162126510560293,2.7975768714129026,-0.19806322542449376,0.9927055249531092 | 3,381 |
Inner mitochondrial membrane protein complex | 28 | 81 | 3.60903 | 0.000307 | O60830,Q99595,P14406,O14925,Q96CU9,O43676,Q16718,Q9UDW1,O43674,Q13505,Q9Y6M9,O75964,P56134,P00846,Q8IYU8,Q9NX63,P13073,Q9BPX6,O75431,Q86Y39,Q5HYI7,Q9Y4W6,Q9Y5J7,P03886,P06576,P00403,P56556,O14949 | Localization | GO Cellular component | msigdb_gocc | 0,1,9,264,14,17,154,28,287,36,436,46,304,54,451,195,201,471,88,350,364,382,115,247,371,380,125,127 | 1893,659,264,127,287,17,0,2562,1760,1863,88,1539,825,1576,46,1210,2381,646,1360,1256,380,54,247,371,1050,1517,1367,1542,201,9,808,880,3206,711,755,512,914,756,3305,2196,1491,1468,1103,2356,1470,3199,3285,1677,304,741,865,125,36,154,2458,833,959,834,364,697,1421,350,451,1085,14,1197,1,1044,471,1045,1151,484,1173,195,3336,28,2248,382,1858,115,436 | -0.233383556658795,0.66884230281273,1.3707265386892524,1.9625683440442812,1.3240769098404388,3.5198547952428183,5.073603072328636,-0.610941794333371,-0.16284975656285822,-0.21570997527597668,2.314221925162671,-0.04043100103272851,0.47039145099938634,-0.057841396040278596,2.7975768714129026,0.16651906993514767,-0.5017886709334725,0.6852366133893191,0.06349529754497407,0.13227671324131024,1.088262751441023,2.727529421964283,1.417209198502823,1.1041194035027075,0.26866237124034603,-0.02304631237539939,0.06349529754497407,-0.04043100103272851,1.6015036764204846,3.978155059571171,0.4870521174821247,0.4202725426034364,-1.211869368833104,0.5865431038553878,0.5368984476537072,0.8641627985338416,0.3867449477923637,0.5368984476537072,-1.5451951225647298,-0.39367279234365044,-0.0056872218402178,0.011646378050987276,0.2347111094017979,-0.48369809024111093,0.011646378050987276,-1.1925822871771383,-1.4460659147478525,-0.1102279128477972,1.2616146868698537,0.5534689593446168,0.4370017529662837,1.9922224857685245,2.9781043788454484,1.8283105702783014,-0.5380563923449663,0.47039145099938634,0.3531245121268438,0.47039145099938634,1.1199563718210412,0.6195286455637697,0.04623753210788857,1.151571535639279,0.9606924188585974,0.2516987221968761,3.665405898737808,0.18360351475980163,4.964986919891834,0.285602152936856,0.9285979925872347,0.285602152936856,0.21769943580617096,0.9125200992112816,0.20066360371072753,1.6623656284021715,-1.910089858268988,3.210810725503896,-0.41162126510560293,1.088262751441023,-0.19806322542449376,2.09550357539617,0.9927055249531092 | 3,381 |
Protein localization | 34 | 81 | 3.587812 | 0.000333 | O60830,Q99595,O15254,Q9NS69,P40855,P05067,O14925,P09601,P50542,P49069,Q8N4H5,Q13505,O43681,Q9Y5Y5,P50402,Q13011,Q9BY49,O96008,Q9Y5L4,O43765,Q15067,Q9NX63,Q5JRX3,P21796,P51648,Q9Y5J9,Q15388,O75431,P46379,P06576,O75381,Q9Y5J7,Q13190,O60220 | Processes and pathways | Reactome Pathways | msigdb_reactome | 0,1,129,5,256,132,264,13,524,523,33,36,536,301,303,557,309,568,310,191,449,195,197,199,333,84,465,88,476,371,486,115,373,121 | 1276,878,264,1093,949,129,1255,536,191,969,121,0,486,3290,88,1181,2012,898,2155,1336,568,132,371,1050,1709,13,2757,1309,1542,2194,199,1128,756,1837,1102,2356,256,476,523,303,524,2285,333,1374,1442,3325,2984,1001,557,373,36,449,465,959,197,580,3032,2740,1167,33,797,1268,2654,1,3175,2432,309,1045,875,5,195,2275,2952,1331,2248,2438,1858,115,84,310,301 | 0.11511859996624757,0.4202725426034364,1.3707265386892524,0.2347111094017979,0.3531245121268438,1.9477168099260758,0.13227671324131024,0.8318208221873443,1.6775374510295888,0.33627924845100304,2.0070251955300082,5.073603072328636,0.8964216526892619,-1.4658172577816313,2.314221925162671,0.18360351475980163,-0.3043485498283727,0.40352030450058385,-0.37575235994719464,0.08072799489487778,0.7831506553954769,1.9328488984240189,1.1041194035027075,0.26866237124034603,-0.12774223079298147,3.783448138156203,-0.7396367924488996,0.09793572799284321,-0.04043100103272851,-0.39367279234365044,1.6319696996489776,0.21769943580617096,0.5368984476537072,-0.19806322542449376,0.2347111094017979,-0.48369809024111093,1.3862392263267762,0.9125200992112816,0.8480022389189762,1.2616146868698537,0.8480022389189762,-0.44760283593211736,1.1831087956745996,0.06349529754497407,0.028954594033709185,-1.7870173720445042,-0.9073124362309171,0.3194104967216977,0.7993951082889633,1.1041194035027075,2.9781043788454484,0.9606924188585974,0.9285979925872347,0.3531245121268438,1.647176397021248,0.7668850339236268,-0.9449212358676787,-0.7211611336557268,0.20066360371072753,3.046937180331755,0.5036901138602248,0.13227671324131024,-0.6659163242058336,4.964986919891834,-1.1349269369210717,-0.5199080611106346,1.2459517836247969,0.285602152936856,0.4370017529662837,4.32249087085326,1.6623656284021715,-0.4295979040509883,-0.8698314423424568,0.09793572799284321,-0.41162126510560293,-0.5199080611106346,-0.19806322542449376,2.09550357539617,2.3575511001107285,1.2459517836247969,1.2772585855164569 | 3,381 |
Abnormality of the larynx | 20 | 51 | 3.362759 | 0.000772 | P02545,P21964,Q14203,Q01082,P54198,P25054,Q13501,Q2M1P5,Q68CQ7,Q92804,P36543,P35637,Q96HY6,P07602,Q14739,Q9UHX1,Q15165,P43243,O00192,Q9NZJ7 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 4,12,409,540,539,44,429,575,185,63,324,77,205,81,592,360,353,616,370,377 | 370,2530,3209,2597,2754,4,1540,81,2189,849,662,3264,12,44,1544,1078,77,324,2019,1990,616,1130,1640,2164,2677,539,1313,540,2636,429,1344,409,592,2233,353,2482,575,185,1084,1653,762,2742,63,1880,205,1299,377,2524,360,2151,1457 | 1.1041194035027075,-0.5926763630965615,-1.2311910594807025,-0.6292368396202702,-0.7396367924488996,4.32249087085326,-0.04043100103272851,2.4007449963234015,-0.39367279234365044,0.45370802586662823,0.66884230281273,-1.3870322116472107,3.8486291662636134,2.853367256267709,-0.04043100103272851,0.2516987221968761,2.4294663659270506,1.1988483827647884,-0.3043485498283727,-0.2865664640305207,0.7179603649304444,0.21769943580617096,-0.09273974181183568,-0.37575235994719464,-0.6843010420962635,0.8318208221873443,0.09793572799284321,0.8318208221873443,-0.6475616366576715,0.9927055249531092,0.08072799489487778,1.0405739895843595,0.7505981648073553,-0.41162126510560293,1.1357737261005323,-0.5562337972034157,0.7831506553954769,1.7229490341498392,0.2516987221968761,-0.09273974181183568,0.5368984476537072,-0.7211611336557268,2.628876532164271,-0.21570997527597668,1.5862442345229415,0.11511859996624757,1.1041194035027075,-0.5744404092580189,1.1357737261005323,-0.3578598430231122,0.028954594033709185 | 3,381 |
Dementia | 28 | 59 | 3.346881 | 0.000817 | P05067,Q14203,Q8IY17,P31483,O43464,O43681,Q14108,P22626,P20700,Q9NQZ5,Q13501,P04062,O96008,P00846,Q9Y487,P36543,P35637,P07602,P06865,O60220,P43243,Q9Y287,P03886,P21912,Q9UBB4,Q9NZJ7,P00403,Q06787 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 132,409,411,416,162,536,554,298,297,561,429,687,568,54,64,324,77,81,721,121,616,245,247,755,641,377,380,634 | 924,1513,162,536,121,767,2828,848,568,380,54,247,687,1577,132,721,81,849,3143,1100,297,755,298,2979,1030,2196,416,77,324,1673,1615,616,2710,1935,1313,1584,1647,634,2636,429,1344,554,409,1554,1719,411,1877,2135,3107,1198,1351,1426,3272,561,377,641,1457,245,64 | 0.3699463810201887,-0.02304631237539939,1.7982920845921333,0.8318208221873443,2.0070251955300082,0.5203055281119934,-0.7952479551162744,0.45370802586662823,0.7831506553954769,1.088262751441023,2.727529421964283,1.417209198502823,0.6359884017355526,-0.057841396040278596,1.9328488984240189,0.5700171494918655,2.4007449963234015,0.45370802586662823,-1.0966598820951519,0.2347111094017979,1.2772585855164569,0.5368984476537072,1.2772585855164569,-0.9073124362309171,0.285602152936856,-0.39367279234365044,1.0246378972585815,2.4294663659270506,1.1988483827647884,-0.1102279128477972,-0.07527760638334166,0.7179603649304444,-0.7027159312432755,-0.25108408655359427,0.09793572799284321,-0.057841396040278596,-0.09273974181183568,0.7016092735780922,-0.6475616366576715,0.9927055249531092,0.08072799489487778,0.8156184711857695,1.0405739895843595,-0.04043100103272851,-0.12774223079298147,1.0405739895843595,-0.21570997527597668,-0.3578598430231122,-1.0205272889889005,0.18360351475980163,0.08072799489487778,0.04623753210788857,-1.3870322116472107,0.7993951082889633,1.1041194035027075,0.7016092735780922,0.028954594033709185,1.4326666084227007,2.628876532164271 | 3,381 |
Electron transport chain oxphos system in mitochondria | 15 | 53 | 3.314912 | 0.000917 | O43674,P14406,P13073,O75964,P56134,O43676,P00403,O75880,P00846,P03886,P06576,Q16718,Q9UDW1,P56556,O14949 | Processes and pathways | WikiPathways | msigdb_wp | 287,9,201,46,304,17,380,275,54,247,371,154,28,125,127 | 1893,659,127,287,17,2562,1760,1863,1539,825,275,1576,46,1210,2381,646,1360,1256,380,54,247,2646,371,1517,1367,1309,1542,201,9,808,880,3206,711,755,512,914,756,3305,2196,1491,1103,1470,3199,3285,1677,304,865,125,154,2458,28,642,436 | -0.233383556658795,0.66884230281273,1.9625683440442812,1.3240769098404388,3.5198547952428183,-0.610941794333371,-0.16284975656285822,-0.21570997527597668,-0.04043100103272851,0.47039145099938634,1.355195299175073,-0.057841396040278596,2.7975768714129026,0.16651906993514767,-0.5017886709334725,0.6852366133893191,0.06349529754497407,0.13227671324131024,1.088262751441023,2.727529421964283,1.417209198502823,-0.6659163242058336,1.1041194035027075,-0.02304631237539939,0.06349529754497407,0.09793572799284321,-0.04043100103272851,1.6015036764204846,3.978155059571171,0.4870521174821247,0.4202725426034364,-1.211869368833104,0.5865431038553878,0.5368984476537072,0.8641627985338416,0.3867449477923637,0.5368984476537072,-1.5451951225647298,-0.39367279234365044,-0.0056872218402178,0.2347111094017979,0.011646378050987276,-1.1925822871771383,-1.4460659147478525,-0.1102279128477972,1.2616146868698537,0.4370017529662837,1.9922224857685245,1.8283105702783014,-0.5380563923449663,3.210810725503896,0.7016092735780922,0.9927055249531092 | 3,381 |
Cardiac muscle contraction | 11 | 22 | 3.305164 | 0.000949 | P22695,P14406,P13073,P09493,P05026,P67936,P00403,Q9UDW1,O14548,P06753,O14949 | Processes and pathways | KEGG Pathways | msigdb_kegg | 512,9,201,79,688,149,380,28,659,218,127 | 659,127,380,911,688,218,1050,79,1517,1367,201,9,808,880,994,711,512,1491,1470,1616,149,28 | 0.66884230281273,1.9625683440442812,1.088262751441023,0.3867449477923637,0.6359884017355526,1.5403594847627644,0.26866237124034603,2.4151131078172017,-0.02304631237539939,0.06349529754497407,1.6015036764204846,3.978155059571171,0.4870521174821247,0.4202725426034364,0.3194104967216977,0.5865431038553878,0.8641627985338416,-0.0056872218402178,0.011646378050987276,-0.07527760638334166,1.8432945876025781,3.210810725503896 | 3,381 |
Negative regulation of mrna metabolic process | 24 | 46 | 3.220884 | 0.001278 | P38159,P07910,Q16629,Q16539,P22626,O60506,P98175,Q13151,Q92804,Q9H074,P11940,P67809,P35637,Q13242,P26368,P61978,Q14011,Q15287,O75150,Q9NZI8,Q99729,Q14103,Q08211,Q06787 | Processes and pathways | GO Biological process | msigdb_gobp | 133,647,665,791,298,176,439,448,63,194,826,73,77,851,589,214,89,479,862,894,244,500,885,634 | 2930,1706,1927,176,862,1308,1732,647,826,899,298,589,2383,77,133,1080,214,73,439,2574,634,1472,1136,885,2331,2636,448,851,1810,89,500,479,1019,791,665,982,2207,1998,1420,1507,63,244,1694,194,894,1123 | -0.8698314423424568,-0.12774223079298147,-0.25108408655359427,1.7531374146957515,0.4370017529662837,0.09793572799284321,-0.14528280773655003,0.6852366133893191,0.47039145099938634,0.40352030450058385,1.2772585855164569,0.7505981648073553,-0.5017886709334725,2.4294663659270506,1.9328488984240189,0.2516987221968761,1.5556721976735917,2.4724374570925978,0.9767091001145846,-0.610941794333371,0.7016092735780922,0.011646378050987276,0.21769943580617096,0.4202725426034364,-0.4656361884453895,-0.6475616366576715,0.9606924188585974,0.45370802586662823,-0.18044319095933925,2.314221925162671,0.8803025777169821,0.9125200992112816,0.30251816305270063,0.5036901138602248,0.66884230281273,0.33627924845100304,-0.39367279234365044,-0.2865664640305207,0.04623753210788857,-0.0056872218402178,2.628876532164271,1.4326666084227007,-0.1102279128477972,1.6623656284021715,0.4202725426034364,0.2347111094017979 | 3,381 |
Optic disc pallor | 22 | 53 | 3.197687 | 0.001385 | Q9GZY8,O43172,Q96CU9,O43676,Q9H0B6,Q9H061,Q9UG56,Q9Y6M9,Q13277,P00846,P04439,Q8N183,Q9BUK6,Q86Y39,Q8WWV3,Q6P4Q7,Q9Y287,Q9H6K4,P56556,P03886,P51798,Q9Y4W6 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 396,383,14,17,158,30,290,436,306,54,192,468,472,350,351,354,245,375,125,247,497,382 | 924,3228,3289,897,383,17,1795,767,2562,1760,1863,1181,825,2318,646,927,1256,54,247,192,2937,2226,3206,3305,3285,497,125,3328,1001,306,354,350,468,1628,1476,351,855,1423,14,549,1949,472,396,30,158,375,624,1173,1891,290,245,382,436 | 0.3699463810201887,-1.289365574630109,-1.4658172577816313,0.40352030450058385,1.0723863455217324,3.5198547952428183,-0.18044319095933925,0.5203055281119934,-0.610941794333371,-0.16284975656285822,-0.21570997527597668,0.18360351475980163,0.47039145099938634,-0.4656361884453895,0.6852366133893191,0.3699463810201887,0.13227671324131024,2.727529421964283,1.417209198502823,1.6623656284021715,-0.8698314423424568,-0.41162126510560293,-1.211869368833104,-1.5451951225647298,-1.4460659147478525,0.8803025777169821,1.9922224857685245,-1.8278771844311108,0.3194104967216977,1.2459517836247969,1.1357737261005323,1.151571535639279,0.9285979925872347,-0.07527760638334166,0.011646378050987276,1.151571535639279,0.45370802586662823,0.04623753210788857,3.665405898737808,0.8318208221873443,-0.25108408655359427,0.9285979925872347,1.0723863455217324,3.156391655179004,1.8283105702783014,1.1041194035027075,0.7179603649304444,0.20066360371072753,-0.21570997527597668,1.3084896317780137,1.4326666084227007,1.088262751441023,0.9927055249531092 | 3,381 |
Cation transmembrane transporter activity | 28 | 70 | 3.183968 | 0.001453 | O95202,Q9UDW1,O14548,O43772,Q9HD20,Q8NEW0,P56134,Q96QD8,Q70HW3,P05026,O75964,P00846,Q9Y487,Q93050,P13073,P36543,P20674,P61421,Q9Y5K8,Q9HC07,Q13423,Q6P4Q7,P20020,P30825,P06576,P00403,Q9Y6M7,Q96ES6 | Functions | GO Molecular function | msigdb_gomf | 131,28,659,296,47,433,304,559,51,688,46,54,64,71,201,324,711,591,614,95,607,354,740,240,371,380,252,261 | 659,296,969,1576,46,131,380,54,911,688,2646,371,2042,1987,1578,1050,1367,1309,201,994,740,711,1865,3068,914,756,240,1491,1103,324,1673,1470,3199,1036,1643,304,865,591,3146,1110,2126,1413,607,1446,937,354,51,1085,433,1597,71,261,1171,559,1509,1886,2272,1271,1698,95,47,3233,28,1330,2150,3015,64,614,2349,252 | 0.66884230281273,1.2772585855164569,0.33627924845100304,-0.057841396040278596,2.7975768714129026,1.9328488984240189,1.088262751441023,2.727529421964283,0.3867449477923637,0.6359884017355526,-0.6659163242058336,1.1041194035027075,-0.3221580605870234,-0.2865664640305207,-0.057841396040278596,0.26866237124034603,0.06349529754497407,0.09793572799284321,1.6015036764204846,0.3194104967216977,0.5534689593446168,0.5865431038553878,-0.21570997527597668,-0.9826590952942919,0.3867449477923637,0.5368984476537072,1.4481057172341323,-0.0056872218402178,0.2347111094017979,1.1988483827647884,-0.1102279128477972,0.011646378050987276,-1.1925822871771383,0.285602152936856,-0.09273974181183568,1.2616146868698537,0.4370017529662837,0.7505981648073553,-1.0966598820951519,0.2347111094017979,-0.3578598430231122,0.04623753210788857,0.7342899684920763,0.028954594033709185,0.3699463810201887,1.1357737261005323,2.755589935882612,0.2516987221968761,0.9927055249531092,-0.057841396040278596,2.5010113820047586,1.3862392263267762,0.20066360371072753,0.7993951082889633,-0.0056872218402178,-0.21570997527597668,-0.4295979040509883,0.13227671324131024,-0.1102279128477972,2.2707562529589636,2.7975768714129026,-1.289365574630109,3.210810725503896,0.09793572799284321,-0.3578598430231122,-0.9261007824267626,2.628876532164271,0.7342899684920763,-0.4656361884453895,1.4017334253090765 | 3,381 |
Receptor | 16 | 43 | 3.175349 | 0.001497 | Q8WTV0,Q99523,P01130,Q9NS69,P06493,Q07954,Q9UBG0,Q14108,O00264,P30825,O15173,P24390,P98164,Q14739,P10586,O43731 | Functions | Protein Atlas Molecular function | protein_atlas_molecular_function | 259,225,537,5,474,489,138,554,141,240,50,19,428,592,314,92 | 141,1512,1015,1513,50,92,1124,537,991,1900,474,1278,1366,1237,314,1672,1052,2957,2194,19,2447,240,1018,428,489,2129,554,592,636,1446,1083,259,2296,1597,225,1044,3308,5,138,1013,1123,822,2703 | 1.8881463808123733,-0.02304631237539939,0.30251816305270063,-0.02304631237539939,2.769599386688778,2.299748594818239,0.21769943580617096,0.8318208221873443,0.3194104967216977,-0.233383556658795,0.9125200992112816,0.11511859996624757,0.06349529754497407,0.14941016954971006,1.23026980961867,-0.1102279128477972,0.26866237124034603,-0.8885560411599439,-0.39367279234365044,3.4264829524837057,-0.5380563923449663,1.4481057172341323,0.30251816305270063,0.9927055249531092,0.8964216526892619,-0.3578598430231122,0.8156184711857695,0.7505981648073553,0.7016092735780922,0.028954594033709185,0.2516987221968761,1.3862392263267762,-0.44760283593211736,-0.057841396040278596,1.5250288963471914,0.285602152936856,-1.585110386151516,4.32249087085326,1.9179645577932507,0.3194104967216977,0.2347111094017979,0.4870521174821247,-0.6843010420962635 | 3,381 |
Mitochondrial membrane organization | 16 | 48 | 3.145939 | 0.001656 | Q9NX63,O95202,Q13505,Q9NS69,P0DP25,P52789,Q5HYI7,Q9Y5J7,Q9Y5J9,Q9Y5L4,Q8N8Q8,P45880,O60220,O75431,O14737,Q9Y4W6 | Processes and pathways | GO Biological process | msigdb_gobp | 195,131,36,5,294,385,364,115,84,310,341,184,121,88,91,382 | 2932,91,121,767,88,1336,131,1540,2646,1466,2535,294,1309,604,3236,2676,2604,2356,2761,184,954,524,385,915,36,980,833,959,834,364,697,1421,450,984,1780,341,945,5,1151,195,3336,642,2248,382,1858,115,84,310 | -0.8698314423424568,2.299748594818239,2.0070251955300082,0.5203055281119934,2.314221925162671,0.08072799489487778,1.9328488984240189,-0.04043100103272851,-0.6659163242058336,0.011646378050987276,-0.5926763630965615,1.292883545349269,0.09793572799284321,0.7342899684920763,-1.3088274981671097,-0.6843010420962635,-0.6292368396202702,-0.48369809024111093,-0.7396367924488996,1.7229490341498392,0.3531245121268438,0.8480022389189762,1.0723863455217324,0.3867449477923637,2.9781043788454484,0.33627924845100304,0.47039145099938634,0.3531245121268438,0.47039145099938634,1.1199563718210412,0.6195286455637697,0.04623753210788857,0.9606924188585974,0.33627924845100304,-0.16284975656285822,1.1673498693322624,0.3699463810201887,4.32249087085326,0.21769943580617096,1.6623656284021715,-1.910089858268988,0.7016092735780922,-0.41162126510560293,1.088262751441023,-0.19806322542449376,2.09550357539617,2.3575511001107285,1.2459517836247969 | 3,381 |
Tetrapyrrole binding | 9 | 16 | 3.085667 | 0.002031 | P30519,P09601,O00264,Q16850,O15173,O43169,Q8WUJ1,Q6UW02,P53701 | Functions | GO Molecular function | msigdb_gomf | 74,13,141,241,50,83,181,86,316 | 141,50,83,1050,13,1711,74,316,241,86,181,2176,323,1227,747,587 | 1.8881463808123733,2.769599386688778,2.3719640368293593,0.26866237124034603,3.783448138156203,-0.12774223079298147,2.4581284970631354,1.23026980961867,1.4481057172341323,2.34312313256838,1.7380517879985764,-0.37575235994719464,1.2145686983078836,0.16651906993514767,0.5534689593446168,0.7668850339236268 | 3,381 |
Proton transmembrane transporter activity | 17 | 36 | 3.077505 | 0.002087 | Q9Y487,Q13423,O95202,Q93050,P13073,P36543,P06576,P20674,O75964,P56134,P61421,P00846,Q9Y5K8,P00403,Q9UDW1,O14548,Q96ES6 | Functions | GO Molecular function | msigdb_gomf | 64,607,131,71,201,324,371,711,46,304,591,54,614,380,28,659,261 | 659,1576,46,131,380,54,2646,371,1050,1367,1309,201,711,1865,3068,914,756,1491,1103,324,1673,1470,3199,1036,304,865,591,2126,607,71,261,1271,28,1330,64,614 | 0.66884230281273,-0.057841396040278596,2.7975768714129026,1.9328488984240189,1.088262751441023,2.727529421964283,-0.6659163242058336,1.1041194035027075,0.26866237124034603,0.06349529754497407,0.09793572799284321,1.6015036764204846,0.5865431038553878,-0.21570997527597668,-0.9826590952942919,0.3867449477923637,0.5368984476537072,-0.0056872218402178,0.2347111094017979,1.1988483827647884,-0.1102279128477972,0.011646378050987276,-1.1925822871771383,0.285602152936856,1.2616146868698537,0.4370017529662837,0.7505981648073553,-0.3578598430231122,0.7342899684920763,2.5010113820047586,1.3862392263267762,0.13227671324131024,3.210810725503896,0.09793572799284321,2.628876532164271,0.7342899684920763 | 3,381 |
Oxidative phosphorylation | 18 | 62 | 3.050455 | 0.002285 | O43674,Q9Y487,Q93050,P14406,P13073,P36543,O75964,P56134,O43676,P00403,P00846,P03886,P06576,Q16718,Q9UDW1,P56556,Q86Y39,O14949 | Processes and pathways | KEGG Pathways | msigdb_kegg | 287,64,71,9,201,324,46,304,17,380,54,247,371,154,28,125,350,127 | 1893,659,127,287,17,2562,1760,1863,1539,825,1576,46,1210,2381,646,1360,1256,380,54,247,371,1050,1517,1367,201,9,808,880,3206,711,1865,3068,755,512,914,756,3305,2196,1491,1103,324,1673,1470,3199,3285,1677,304,865,125,591,3277,1038,154,2458,350,71,3262,28,1330,64,614,436 | -0.233383556658795,0.66884230281273,1.9625683440442812,1.3240769098404388,3.5198547952428183,-0.610941794333371,-0.16284975656285822,-0.21570997527597668,-0.04043100103272851,0.47039145099938634,-0.057841396040278596,2.7975768714129026,0.16651906993514767,-0.5017886709334725,0.6852366133893191,0.06349529754497407,0.13227671324131024,1.088262751441023,2.727529421964283,1.417209198502823,1.1041194035027075,0.26866237124034603,-0.02304631237539939,0.06349529754497407,1.6015036764204846,3.978155059571171,0.4870521174821247,0.4202725426034364,-1.211869368833104,0.5865431038553878,-0.21570997527597668,-0.9826590952942919,0.5368984476537072,0.8641627985338416,0.3867449477923637,0.5368984476537072,-1.5451951225647298,-0.39367279234365044,-0.0056872218402178,0.2347111094017979,1.1988483827647884,-0.1102279128477972,0.011646378050987276,-1.1925822871771383,-1.4460659147478525,-0.1102279128477972,1.2616146868698537,0.4370017529662837,1.9922224857685245,0.7505981648073553,-1.4066735867376003,0.285602152936856,1.8283105702783014,-0.5380563923449663,1.151571535639279,2.5010113820047586,-1.3674271052580522,3.210810725503896,0.09793572799284321,2.628876532164271,0.7342899684920763,0.9927055249531092 | 3,381 |
Protein transmembrane transport | 13 | 28 | 3.036438 | 0.002394 | O60830,Q99595,Q9UGP8,P49755,Q9NS69,P31751,O14925,Q15629,Q9Y5Y5,O75381,O75298,P50542,Q15388 | Processes and pathways | GO Biological process | msigdb_gobp | 0,1,226,538,5,136,264,72,301,486,555,524,465 | 264,1255,0,555,486,1336,927,568,2757,136,538,524,3325,2571,3146,675,465,72,959,1167,1063,1427,1,1045,5,226,1121,301 | 1.3707265386892524,0.13227671324131024,5.073603072328636,0.7993951082889633,0.8964216526892619,0.08072799489487778,0.3699463810201887,0.7831506553954769,-0.7396367924488996,1.9179645577932507,0.8318208221873443,0.8480022389189762,-1.7870173720445042,-0.610941794333371,-1.0966598820951519,0.6524262597868276,0.9285979925872347,2.4867317377474243,0.3531245121268438,0.20066360371072753,0.26866237124034603,0.04623753210788857,4.964986919891834,0.285602152936856,4.32249087085326,1.5250288963471914,0.2347111094017979,1.2772585855164569 | 3,381 |
Heterogeneous | 21 | 48 | 3.032075 | 0.002429 | P02545,O60333,P05067,P21964,P31749,O75330,Q9BQE5,Q14203,O75844,Q13614,P25054,Q2M1P5,P00846,P07196,P01889,P06753,Q15555,Q9HCC0,P03886,P51798,P50570 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 4,511,132,12,269,397,24,409,159,161,44,575,54,69,442,218,374,376,247,497,514 | 511,397,159,2754,569,54,442,4,247,1540,2672,132,218,69,1052,1309,3020,12,44,2906,269,1185,1468,3023,1545,3132,663,514,2710,497,1843,2387,1584,161,1971,409,374,1164,1020,575,1268,3378,24,376,875,2875,1178,2349 | 0.8641627985338416,1.0564901152174682,1.8133097539294933,-0.7396367924488996,0.7831506553954769,2.727529421964283,0.9606924188585974,4.32249087085326,1.417209198502823,-0.04043100103272851,-0.6843010420962635,1.9328488984240189,1.5403594847627644,2.5152764326345016,0.26866237124034603,0.09793572799284321,-0.9449212358676787,3.8486291662636134,2.853367256267709,-0.8511384861420023,1.3707265386892524,0.18360351475980163,0.011646378050987276,-0.9449212358676787,-0.04043100103272851,-1.0775767957654838,0.66884230281273,0.8641627985338416,-0.7027159312432755,0.8803025777169821,-0.19806322542449376,-0.5017886709334725,-0.057841396040278596,1.8133097539294933,-0.2688116827850815,1.0405739895843595,1.1041194035027075,0.20066360371072753,0.30251816305270063,0.7831506553954769,0.13227671324131024,-6.306383079119281,3.278550011009387,1.1041194035027075,0.4370017529662837,-0.8138468931391319,0.20066360371072753,-0.4656361884453895 | 3,381 |
Metalloprotease | 11 | 29 | 2.969485 | 0.002983 | Q9NZ08,Q6P179,Q5JRX3,Q99797,Q9BYT8,P42892,Q9UIQ6,P55786,P09960,O75976,O75844 | Functions | Protein Atlas Molecular function | protein_atlas_molecular_function | 289,163,197,7,368,140,111,113,337,288,159 | 910,879,1181,159,288,1362,337,3198,2194,140,2329,113,722,2261,197,163,2023,777,1296,798,7,368,2992,1887,2795,2064,289,111,382 | 0.3867449477923637,0.4202725426034364,0.18360351475980163,1.8133097539294933,1.3240769098404388,0.06349529754497407,1.1673498693322624,-1.1925822871771383,-0.39367279234365044,1.9030637360185523,-0.4656361884453895,2.1248688461959304,0.5700171494918655,-0.4295979040509883,1.647176397021248,1.7982920845921333,-0.3043485498283727,0.5203055281119934,0.11511859996624757,0.5036901138602248,4.144909340259825,1.1199563718210412,-0.9073124362309171,-0.21570997527597668,-0.7581430518565561,-0.3221580605870234,1.3084896317780137,2.154171009391761,1.088262751441023 | 3,381 |
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