term
stringlengths
2
121
overlap
int64
6
281
setsize
int64
7
499
score
float64
1.96
10.6
pval
float64
0
0.05
edge
stringlengths
41
1.97k
type
stringclasses
5 values
subtype
stringclasses
24 values
subtype_key
stringclasses
24 values
edge_idxs
stringlengths
11
1.17k
ann_idxs
stringlengths
19
2.31k
ann_vals
stringlengths
124
9.94k
sig_size
int64
2.2k
3.73k
Abnormal biliary tract morphology
10
21
2.69314
0.007078
P09601,O43681,Q14108,Q5XKP0,Q14739,P51659,Q9NSD9,Q9UJW0,P50542,Q10713
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
285,266,104,172,76,361,154,21,313,222
266,993,633,777,285,1715,2725,1582,313,361,222,761,104,76,172,1313,1947,154,425,21,1856
1.1650436541393152,0.09941714153263233,0.4796375690603033,0.3095599986277176,1.1194220763424934,-0.3427663604137081,-1.6107564567697954,-0.26689078457945037,1.0734929151074688,0.9494732169881561,1.374016616607502,0.3267683908998871,2.046338095095178,2.372865186563945,1.591116683200521,-0.09943703415829816,-0.45833220142630116,1.7041986344809297,0.8549403888279615,3.385861236908578,-0.4002819322572054
2,773
Protein maturation
23
64
2.691318
0.007117
P67812,Q99797,Q92542,Q8TAD4,Q5JRX3,Q96HE7,Q15005,O75844,O00170,Q12797,Q9UG56,Q92896,P49366,P62942,Q10713,Q9NQH7,Q8TCT9,Q15392,Q86UY6,P42892,Q96TA2,P35670,O76024
Processes and pathways
GO Biological process
msigdb_gobp
5,387,424,168,175,177,315,56,445,195,196,471,467,220,222,225,98,99,100,110,376,249,367
445,1891,1861,499,56,670,2684,367,1287,2543,2628,2091,2128,2153,1547,2720,2094,1647,249,1236,1032,1123,110,467,1692,2748,1453,957,220,5,1102,222,195,1726,2032,315,99,937,175,1530,701,1064,2622,100,168,98,424,471,177,736,376,387,2348,1276,1165,1378,1348,225,969,2639,196,630,2121,555
0.7911712365778563,-0.43892197167724356,-0.41957202948870276,0.66177751226445,2.6608541324132817,0.42907668779468716,-1.4025446082197535,0.9338096000880001,-0.09943703415829816,-1.0069696246438355,-1.1576949635950773,-0.556303522731768,-0.5760850691049697,-0.5959301513849129,-0.2480641098102342,-1.5638395884882637,-0.556303522731768,-0.30471398246034614,1.2404092037293961,-0.06281812401808029,0.08159248636584522,0.00979464113285314,2.006139977002886,0.7267883475768012,-0.32371131794603986,-2.2585346900595407,-0.19191900263943315,0.13491897416252877,1.374016616607502,4.017298843354599,0.027819650621533694,1.374016616607502,1.5050886200820657,-0.3427663604137081,-0.5169291204252513,1.0734929151074688,2.099586937710835,0.152596792346211,1.5768521422780388,-0.22929351713387358,0.3951515110109617,0.06371823925309218,-1.1359288896386077,2.086311753021363,1.6195587374943998,2.1128376187786273,0.8549403888279615,0.7267883475768012,1.5768521422780388,0.36104948014525085,0.9338096000880001,0.918109512811578,-0.7366663610142645,-0.08110123928284446,-0.0082812963420422,-0.136268113638341,-0.11782587038440924,1.3592986669267102,0.13491897416252877,-1.1795408022055565,1.5050886200820657,0.49640508473295136,-0.556303522731768,0.5961239946346427
2,773
Primary active transmembrane transporter activity
22
48
2.683734
0.007281
P13073,Q9Y6M9,P05023,Q9HD20,O43676,O96000,P33527,O95168,P16615,Q9UDW1,P08574,P06576,P20020,Q9P0J0,P00403,Q9Y5K8,O75027,Q15388,P35670,P20674,P08183,P51970
Functions
GO Molecular function
msigdb_gomf
130,134,397,29,34,293,166,672,300,52,557,431,455,226,227,631,233,620,249,501,368,636
929,1543,34,233,1636,1385,1176,672,2278,1680,293,227,397,431,368,557,1388,130,300,2260,455,501,997,2427,829,2306,1099,166,249,932,1360,757,2677,1363,636,2602,690,1427,620,884,1460,29,990,226,52,1277,631,134
0.152596792346211,-0.2480641098102342,3.0786729040592555,1.3001107448304974,-0.30471398246034614,-0.15476413359326763,-0.026408504701637636,0.42907668779468716,-0.6961258399380261,-0.32371131794603986,1.1041467746508826,1.344549265567791,0.9023727529414285,0.8231316615590936,0.9338096000880001,0.5796084169446801,-0.15476413359326763,1.829279487006994,1.0888371155747185,-0.6759556600324522,0.7751335984561154,0.66177751226445,0.09941714153263233,-0.8392101662750319,0.2576600004388149,-0.7163625657538544,0.027819650621533694,1.6195587374943998,1.2404092037293961,0.152596792346211,-0.136268113638341,0.3267683908998871,-1.3347549057430848,-0.136268113638341,0.4796375690603033,-1.0926332934479581,0.41213607006932595,-0.17331430397827757,0.49640508473295136,0.20534163014615786,-0.19191900263943315,3.239504168358267,0.11719253012638,1.3592986669267102,2.721996774098279,-0.08110123928284446,0.49640508473295136,1.8016746579283256
2,773
Delayed cranial suture closure
11
28
2.677155
0.007425
Q08J23,P48651,P51659,O75381,Q15813,P16435,O75431,Q32P28,Q8NCH0,Q9Y487,O75844
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
198,312,361,396,241,369,88,188,282,163,56
1204,396,88,1862,441,56,993,369,2649,1870,932,1360,1720,635,1236,312,361,2412,1996,198,1459,241,188,282,1248,1628,1502,163
-0.044587330503544284,0.9023727529414285,2.1918330750978643,-0.41957202948870276,0.8071705185983409,2.6608541324132817,0.09941714153263233,0.9338096000880001,-1.2234745726017855,-0.41957202948870276,0.152596792346211,-0.136268113638341,-0.3427663604137081,0.4796375690603033,-0.06281812401808029,1.0734929151074688,0.9494732169881561,-0.8185629381819824,-0.4973353200537405,1.4906467407975372,-0.19191900263943315,1.2703248377219385,1.5338827670309567,1.134663203113307,-0.06281812401808029,-0.2857739408302759,-0.21057861160200061,1.66200633565837
2,773
Endomembrane system organization
43
137
2.672187
0.007536
Q9UH99,Q9UNZ2,P27361,O43681,Q8NHH9,Q6IAA8,O95197,Q14789,Q96A33,Q9NXE4,P53350,P41440,Q8IXJ6,P16615,O15260,P50542,P50402,O75844,Q8N4V1,P40616,Q9NQC3,Q8N1F7,P51790,Q9P2W9,Q9UQB8,Q15629,Q9Y6Y8,P31751,Q7L5D6,Q86XL3,P53990,P28482,Q92783,O15027,P57088,Q14108,O43760,Q9NPA0,P49755,Q15006,Q8WUX9,Q13190,Q9UID3
Processes and pathways
GO Biological process
msigdb_gobp
517,519,262,266,529,662,22,281,160,554,548,171,176,300,180,313,433,56,61,567,63,449,447,67,68,69,604,210,470,93,612,354,356,605,502,104,124,245,370,639,641,637,518
753,2434,1986,824,1635,975,1145,864,1954,605,1475,180,2303,1713,1119,266,124,1229,2126,865,1750,992,1862,1286,56,1419,1507,1206,22,1420,1231,993,1031,1896,300,2393,845,1548,262,354,711,210,1647,1211,567,171,1934,713,2025,953,1362,370,433,313,897,1053,447,548,612,689,502,1965,1454,1695,1213,1216,1336,881,1429,812,1339,2747,1365,899,660,1806,763,637,104,1457,1059,281,639,2444,2192,1942,69,964,1080,2367,662,470,720,1811,93,1667,176,449,61,940,1494,529,1733,1813,641,1086,356,160,2448,2464,1191,1015,1163,2420,923,245,63,1436,554,1572,1783,1090,67,517,518,926,2202,2014,1091,519,68,2640,1473,2554,2047,1255,604
0.3267683908998871,-0.8599277461978309,-0.4973353200537405,0.2576600004388149,-0.30471398246034614,0.11719253012638,-0.0082812963420422,0.22282806736936095,-0.4778031665294185,0.5131299780208094,-0.21057861160200061,1.548235327001688,-0.7163625657538544,-0.3427663604137081,0.00979464113285314,1.1650436541393152,1.8841683861125587,-0.06281812401808029,-0.5760850691049697,0.22282806736936095,-0.3618795277123087,0.09941714153263233,-0.41957202948870276,-0.09943703415829816,2.6608541324132817,-0.17331430397827757,-0.22929351713387358,-0.044587330503544284,3.352334616639615,-0.17331430397827757,-0.06281812401808029,0.09941714153263233,0.08159248636584522,-0.43892197167724356,1.0888371155747185,-0.7979854974629659,0.2402674242042158,-0.2480641098102342,1.195289557247196,0.9651005639747406,0.3781227390966732,1.4179833366718122,-0.30471398246034614,-0.044587330503544284,0.5630514743848866,1.591116683200521,-0.45833220142630116,0.3781227390966732,-0.5169291204252513,0.13491897416252877,-0.136268113638341,0.9338096000880001,0.8231316615590936,1.0734929151074688,0.18780780970224395,0.06371823925309218,0.7911712365778563,0.5961239946346427,0.5131299780208094,0.41213607006932595,0.66177751226445,-0.4778031665294185,-0.19191900263943315,-0.32371131794603986,-0.044587330503544284,-0.044587330503544284,-0.11782587038440924,0.20534163014615786,-0.17331430397827757,0.27500609285862937,-0.11782587038440924,-2.1023206276155575,-0.136268113638341,0.18780780970224395,0.4459736330867459,-0.3810512424874989,0.3267683908998871,0.4796375690603033,2.046338095095178,-0.19191900263943315,0.06371823925309218,1.134663203113307,0.4796375690603033,-0.8599277461978309,-0.615839256133415,-0.45833220142630116,2.4617182325925935,0.13491897416252877,0.04579407141593343,-0.7570377557857778,0.4459736330867459,0.7267883475768012,0.3781227390966732,-0.3810512424874989,2.1655974376673623,-0.30471398246034614,1.5768521422780388,0.7911712365778563,2.5992012852779514,0.152596792346211,-0.21057861160200061,0.6290320310309162,-0.3427663604137081,-0.3810512424874989,0.4796375690603033,0.04579407141593343,0.9651005639747406,1.66200633565837,-0.8599277461978309,-0.8807162496476115,-0.026408504701637636,0.09941714153263233,-0.0082812963420422,-0.8185629381819824,0.17022630011855963,1.2553833203983125,2.5619604388691277,-0.17331430397827757,0.5961239946346427,-0.2480641098102342,-0.3618795277123087,0.04579407141593343,2.499469862693214,0.6454249718956354,0.6454249718956354,0.17022630011855963,-0.615839256133415,-0.4973353200537405,0.04579407141593343,0.6454249718956354,2.486907600894611,-1.1795408022055565,-0.19191900263943315,-1.0069696246438355,-0.5169291204252513,-0.06281812401808029,0.5298125052139352
2,773
Sensorimotor neuropathy
11
28
2.672179
0.007536
P00846,P00403,Q9NZJ7,P07196,P51659,O60313,P41440,P05023,O95831,Q92989,Q9Y2R0
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
1,227,425,383,361,458,171,397,278,541,31
824,2229,458,278,227,1,397,383,777,710,1263,2334,1648,171,1519,361,1334,2186,1301,960,1432,1916,1434,541,1046,425,31,555
0.2576600004388149,-0.6558515089254989,0.7590573852352058,1.134663203113307,1.344549265567791,5.209596006329733,0.9023727529414285,0.918109512811578,0.3095599986277176,0.3781227390966732,-0.08110123928284446,-0.7366663610142645,-0.30471398246034614,1.591116683200521,-0.22929351713387358,0.9494732169881561,-0.11782587038440924,-0.615839256133415,-0.09943703415829816,0.13491897416252877,-0.17331430397827757,-0.43892197167724356,-0.17331430397827757,0.6125984519295641,0.08159248636584522,0.8549403888279615,3.2053264213068733,0.5961239946346427
2,773
Metalloprotease
16
37
2.667232
0.007648
Q9Y4W6,Q99797,O95630,O43847,Q9NZ08,P42892,P22695,Q5JRX3,Q7Z2K6,Q96TA2,P55786,Q9BYT8,O75844,Q9UIQ6,Q10713,O00303
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
555,387,453,508,108,110,398,175,114,376,23,219,56,352,222,318
318,825,545,508,1861,56,453,892,1791,2502,1389,398,2570,1099,110,1266,716,23,222,1659,2495,175,623,965,114,1371,1626,1067,2006,1879,376,387,219,1709,108,352,555
1.0581139876819772,0.2576600004388149,0.5961239946346427,0.6454249718956354,-0.41957202948870276,2.6608541324132817,0.7751335984561154,0.18780780970224395,-0.3810512424874989,-0.9435131294526775,-0.15476413359326763,0.9023727529414285,-1.049648621318993,0.027819650621533694,2.006139977002886,-0.08110123928284446,0.3781227390966732,3.341126344179749,1.374016616607502,-0.30471398246034614,-0.9225083508928148,1.5768521422780388,0.49640508473295136,0.13491897416252877,1.979215045184117,-0.136268113638341,-0.2857739408302759,0.06371823925309218,-0.4973353200537405,-0.41957202948870276,0.9338096000880001,0.918109512811578,1.388703273348437,-0.32371131794603986,2.046338095095178,0.980691839776418,0.5961239946346427
2,773
Nonalcoholic fatty liver disease
11
48
2.657042
0.007883
P13073,O43676,Q9P0J0,O96000,Q9Y6M9,P00403,P14406,P31751,Q9UDW1,Q86Y39,O14949
Processes and pathways
WikiPathways
msigdb_wp
130,34,226,293,134,227,18,210,52,86,55
929,55,34,1636,1385,1176,672,2278,1680,293,227,1259,557,951,1388,130,18,779,756,2260,501,311,398,2306,2095,711,210,1099,1032,757,1294,2677,636,933,2602,1965,1768,833,1058,937,884,1460,86,1947,490,226,52,134
0.152596792346211,2.6608541324132817,3.0786729040592555,-0.30471398246034614,-0.15476413359326763,-0.026408504701637636,0.42907668779468716,-0.6961258399380261,-0.32371131794603986,1.1041467746508826,1.344549265567791,-0.08110123928284446,0.5796084169446801,0.13491897416252877,-0.15476413359326763,1.829279487006994,3.4081310510533864,0.3095599986277176,0.3267683908998871,-0.6759556600324522,0.66177751226445,1.0734929151074688,0.9023727529414285,-0.7163625657538544,-0.556303522731768,0.3781227390966732,1.4179833366718122,0.027819650621533694,0.08159248636584522,0.3267683908998871,-0.09943703415829816,-1.3347549057430848,0.4796375690603033,0.152596792346211,-1.0926332934479581,-0.4778031665294185,-0.3618795277123087,0.2576600004388149,0.06371823925309218,0.152596792346211,0.20534163014615786,-0.19191900263943315,2.2310085155951622,-0.45833220142630116,0.6943623315630637,1.3592986669267102,2.721996774098279,1.8016746579283256
2,773
Postaxial polydactyly
6
14
2.656386
0.007898
P61978,Q15125,O43924,Q14739,O75845,Q10713
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
201,74,10,76,143,222
10,143,1547,2649,1150,201,355,222,76,74,1313,2371,1570,1320
3.7983699214209543,1.7182066280572748,-0.2480641098102342,-1.2234745726017855,-0.0082812963420422,1.4761747942022012,0.9651005639747406,1.374016616607502,2.372865186563945,2.4237707360140495,-0.09943703415829816,-0.7570377557857778,-0.2480641098102342,-0.09943703415829816
2,773
Biliary tract abnormality
11
24
2.628727
0.008571
P09601,O43681,Q14108,Q5XKP0,Q14739,P51659,Q9NSD9,Q9UJW0,P50542,O95202,Q10713
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
285,266,104,172,76,361,154,21,313,341,222
266,341,586,993,633,777,285,1715,2725,1582,313,361,222,761,2239,104,76,172,1313,1947,154,425,21,1856
1.1650436541393152,1.0117669641918954,0.5298125052139352,0.09941714153263233,0.4796375690603033,0.3095599986277176,1.1194220763424934,-0.3427663604137081,-1.6107564567697954,-0.26689078457945037,1.0734929151074688,0.9494732169881561,1.374016616607502,0.3267683908998871,-0.6558515089254989,2.046338095095178,2.372865186563945,1.591116683200521,-0.09943703415829816,-0.45833220142630116,1.7041986344809297,0.8549403888279615,3.385861236908578,-0.4002819322572054
2,773
Cristae formation
9
20
2.6207
0.008775
P00846,P56385,Q9Y512,Q16891,Q13505,Q6UXV4,Q5XKP0,O75431,O75964
Processes and pathways
Reactome Pathways
msigdb_reactome
1,322,197,421,11,303,172,88,122
88,728,122,1,431,1234,730,1549,712,2589,2671,1128,322,11,421,172,303,629,532,197
2.1918330750978643,0.36104948014525085,1.8978244995764642,5.209596006329733,0.8231316615590936,-0.06281812401808029,0.36104948014525085,-0.2480641098102342,0.3781227390966732,-1.0711024232199626,-1.289991216052848,0.00979464113285314,1.0581139876819772,3.6489374258930978,0.8549403888279615,1.591116683200521,1.0888371155747185,0.49640508473295136,0.6290320310309162,1.5050886200820657
2,773
Abnormality of fontanelles
17
44
2.605602
0.009171
Q6NUK1,P98175,Q08J23,Q15125,Q9Y619,P48651,P51659,O75381,Q15813,Q9BT22,P50542,P16435,Q32P28,Q8NCH0,O94761,Q9Y487,O75844
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
346,355,198,74,203,312,361,396,241,379,313,369,188,282,216,163,56
1204,1747,396,1637,1862,441,56,216,993,2451,369,501,2649,2180,2022,932,2379,2362,1360,635,879,1994,312,313,361,2412,1996,355,812,832,198,1593,74,1459,241,1009,188,346,282,1248,379,1502,163,203
-0.044587330503544284,-0.3618795277123087,0.9023727529414285,-0.30471398246034614,-0.41957202948870276,0.8071705185983409,2.6608541324132817,1.388703273348437,0.09941714153263233,-0.8807162496476115,0.9338096000880001,0.66177751226445,-1.2234745726017855,-0.615839256133415,-0.5169291204252513,0.152596792346211,-0.7774772867789987,-0.7570377557857778,-0.136268113638341,0.4796375690603033,0.20534163014615786,-0.4973353200537405,1.0734929151074688,1.0734929151074688,0.9494732169881561,-0.8185629381819824,-0.4973353200537405,0.9651005639747406,0.27500609285862937,0.2576600004388149,1.4906467407975372,-0.26689078457945037,2.4237707360140495,-0.19191900263943315,1.2703248377219385,0.09941714153263233,1.5338827670309567,0.980691839776418,1.134663203113307,-0.06281812401808029,0.9338096000880001,-0.21057861160200061,1.66200633565837,1.4761747942022012
2,773
Sterol biosynthetic process
8
23
2.605404
0.009177
Q15392,P37268,Q15125,P11413,Q14739,O75845,Q16850,Q15800
Processes and pathways
GO Biological process
msigdb_gobp
99,38,74,267,76,143,120,187
143,1387,1754,267,1149,369,38,2307,1238,955,2441,2338,832,1058,2313,496,76,74,2070,99,901,187,120
1.7182066280572748,-0.15476413359326763,-0.3618795277123087,1.1650436541393152,-0.0082812963420422,0.9338096000880001,2.949856816516709,-0.7163625657538544,-0.06281812401808029,0.13491897416252877,-0.8599277461978309,-0.7366663610142645,0.2576600004388149,0.06371823925309218,-0.7163625657538544,0.6780898876897556,2.372865186563945,2.4237707360140495,-0.5365850315157712,2.099586937710835,0.18780780970224395,1.5338827670309567,1.9250582352755141
2,773
Cellular ion homeostasis
25
76
2.598312
0.009368
P50897,Q9P246,P27361,Q7L0J3,P05023,Q9HD20,Q9Y487,P09601,Q8N511,Q96A33,Q16891,Q8TAD4,Q96HE7,P16615,Q93050,P06576,P51790,P20020,O95202,P62942,P28482,O75027,P35670,Q9Y639,O76024
Processes and pathways
GO Biological process
msigdb_gobp
129,392,262,139,397,29,163,285,35,160,421,168,177,300,53,431,447,455,341,220,354,233,249,255,367
1634,1635,1145,908,2424,233,499,615,2684,367,341,1420,892,397,431,2751,1896,1261,285,2055,1289,674,300,1547,781,455,262,2654,2094,1685,354,1210,249,1360,129,1053,1652,447,1722,758,2663,690,898,220,1838,1427,833,1558,1367,2002,525,937,421,139,985,460,35,694,168,53,160,857,177,599,1413,2740,29,392,1575,1277,630,1320,163,555,255,2722
-0.30471398246034614,-0.30471398246034614,-0.0082812963420422,0.17022630011855963,-0.8392101662750319,1.3001107448304974,0.66177751226445,0.49640508473295136,-1.4025446082197535,0.9338096000880001,1.0117669641918954,-0.17331430397827757,0.18780780970224395,0.9023727529414285,0.8231316615590936,-2.3651721003221735,-0.43892197167724356,-0.08110123928284446,1.1194220763424934,-0.5365850315157712,-0.09943703415829816,0.42907668779468716,1.0888371155747185,-0.2480641098102342,0.3095599986277176,0.7751335984561154,1.195289557247196,-1.2455639283657367,-0.556303522731768,-0.32371131794603986,0.9651005639747406,-0.044587330503544284,1.2404092037293961,-0.136268113638341,1.8430416218620376,0.06371823925309218,-0.30471398246034614,0.7911712365778563,-0.3427663604137081,0.3267683908998871,-1.267735897113304,0.41213607006932595,0.18780780970224395,1.374016616607502,-0.4002819322572054,-0.17331430397827757,0.2576600004388149,-0.2480641098102342,-0.136268113638341,-0.4973353200537405,0.6290320310309162,0.152596792346211,0.8549403888279615,1.760064137242113,0.11719253012638,0.7590573852352058,3.0786729040592555,0.41213607006932595,1.6195587374943998,2.6731231556376405,1.66200633565837,0.2402674242042158,1.5768521422780388,0.5298125052139352,-0.15476413359326763,-1.9005752483061178,3.239504168358267,0.918109512811578,-0.2480641098102342,-0.08110123928284446,0.49640508473295136,-0.09943703415829816,1.66200633565837,0.5961239946346427,1.2254023183728662,-1.5638395884882637
2,773
Cytochrome complex
7
16
2.596232
0.009425
P13073,P00403,P22695,P14406,Q9UDW1,O14949,P20674
Localization
GO Cellular component
msigdb_gocc
130,227,398,18,52,55,501
929,55,227,557,951,1388,130,18,779,756,501,398,1099,757,52,1856
0.152596792346211,2.6608541324132817,1.344549265567791,0.5796084169446801,0.13491897416252877,-0.15476413359326763,1.829279487006994,3.4081310510533864,0.3095599986277176,0.3267683908998871,0.66177751226445,0.9023727529414285,0.027819650621533694,0.3267683908998871,2.721996774098279,-0.4002819322572054
2,773
Inorganic anion transport
11
20
2.59288
0.009518
P45880,P33527,Q02978,Q9Y277,O43681,P54105,Q9UBX3,Q9C0H2,Q9UHG3,P21796,P08183
Processes and pathways
GO Biological process
msigdb_gobp
64,166,228,169,266,91,79,276,19,155,368
2450,1543,266,368,155,166,64,447,1363,91,2663,1131,228,2509,276,1043,79,19,169,2722
-0.8807162496476115,-0.2480641098102342,1.1650436541393152,0.9338096000880001,1.6901626766427875,1.6195587374943998,2.5370280092342656,0.7911712365778563,-0.136268113638341,2.1655974376673623,-1.267735897113304,0.00979464113285314,1.3297682525174959,-0.9435131294526775,1.1498703359019637,0.08159248636584522,2.3344511368079344,3.397004233181642,1.6195587374943998,-1.5638395884882637
2,773
Hand polydactyly
9
25
2.588496
0.00964
O43924,Q15125,Q14739,O75845,P21964,Q9UHX1,O95202,Q15067,Q10713
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
10,74,76,143,206,239,341,186,222
10,143,341,586,2649,206,2183,1766,355,222,1103,2239,76,1941,186,74,1159,2320,1737,2371,920,1673,1570,239,1320
3.7983699214209543,1.7182066280572748,1.0117669641918954,0.5298125052139352,-1.2234745726017855,1.4471401018248031,-0.615839256133415,-0.3618795277123087,0.9651005639747406,1.374016616607502,0.027819650621533694,-0.6558515089254989,2.372865186563945,-0.45833220142630116,1.5338827670309567,2.4237707360140495,-0.0082812963420422,-0.7163625657538544,-0.3427663604137081,-0.7570377557857778,0.17022630011855963,-0.30471398246034614,-0.2480641098102342,1.2852339236651187,-0.09943703415829816
2,773
Cdt1 association with the cdc6 orc origin complex
10
39
2.556041
0.010587
P28072,P49721,P49720,Q9Y619,Q9UBD5,P28070,P60900,P25787,P25789,P20618
Processes and pathways
Reactome Pathways
msigdb_reactome
263,70,296,203,174,142,302,81,301,279
491,2355,825,2049,827,1148,1096,279,1684,81,1290,301,931,142,263,321,2361,1518,609,296,70,1266,1694,302,783,852,870,1696,1697,801,1060,1061,1706,600,1881,174,1048,1711,203
0.6780898876897556,-0.7570377557857778,0.2576600004388149,-0.5365850315157712,0.2576600004388149,-0.0082812963420422,0.027819650621533694,1.134663203113307,-0.32371131794603986,2.3087285106625295,-0.09943703415829816,1.0888371155747185,0.152596792346211,1.7321867892631835,1.195289557247196,1.0581139876819772,-0.7570377557857778,-0.22929351713387358,0.5131299780208094,1.1041467746508826,2.4364418134826944,-0.08110123928284446,-0.32371131794603986,1.0888371155747185,0.3095599986277176,0.2402674242042158,0.22282806736936095,-0.32371131794603986,-0.32371131794603986,0.29230599528747064,0.06371823925309218,0.06371823925309218,-0.32371131794603986,0.5298125052139352,-0.41957202948870276,1.591116683200521,0.08159248636584522,-0.32371131794603986,1.4761747942022012
2,773
Establishment of protein localization to organelle
41
163
2.552008
0.01071
O60830,P52292,Q99595,Q9NS69,Q99797,O43681,Q96P70,Q92973,O75381,O95831,P55786,O14925,O00410,Q9Y584,Q8N4H5,Q15070,Q9Y2T2,Q9Y5J9,Q5JRX3,P07900,P50542,Q15005,Q8N1F7,Q9Y512,O00170,Q15629,O14737,Q9UGP8,Q7L5D6,Q9Y5L4,O14787,Q10713,O96008,Q9P0J0,Q92783,O95429,P46934,Q14108,Q9Y5M8,Q99623,Q96RL7
Processes and pathways
GO Biological process
msigdb_gobp
0,257,2,3,387,266,400,271,396,278,23,406,405,30,40,42,429,430,175,299,313,315,449,197,445,69,324,214,470,345,476,222,353,226,356,483,234,104,246,377,252
445,1634,405,874,1635,324,476,406,864,606,727,266,1229,1826,0,1608,755,2255,396,1861,1286,2051,775,2357,632,535,483,2586,278,353,993,1446,1031,299,740,1756,2153,1829,866,1758,2653,1329,2209,1832,1642,2649,1930,1961,711,1687,1051,1583,1516,2487,1481,635,713,234,2098,1362,1764,1100,2059,1295,810,313,1125,1553,1053,1652,257,1614,494,1239,742,23,797,1800,957,1937,1695,1213,1803,1591,1657,2187,871,833,1155,222,761,1058,763,1486,104,1527,834,2190,315,2444,42,620,69,1079,2135,1560,539,1109,175,1840,470,562,2139,1110,1664,1811,1667,449,40,1134,986,1066,356,2290,271,400,2244,252,790,2,377,387,2448,770,859,2144,1376,2146,2420,1743,3,1437,226,2118,2173,2174,214,1574,1575,1953,565,2746,2530,2014,1439,1856,429,2554,197,30,430,345,246
0.7911712365778563,-0.30471398246034614,0.8865991164842625,0.20534163014615786,-0.30471398246034614,1.0427001461522951,0.7105950751419811,0.8865991164842625,0.22282806736936095,0.5131299780208094,0.36104948014525085,1.1650436541393152,-0.06281812401808029,-0.4002819322572054,5.280310292530859,-0.2857739408302759,0.3267683908998871,-0.6759556600324522,0.9023727529414285,-0.41957202948870276,-0.09943703415829816,-0.5365850315157712,0.3095599986277176,-0.7570377557857778,0.4796375690603033,0.6125984519295641,0.6943623315630637,-1.0711024232199626,1.134663203113307,0.9651005639747406,0.09941714153263233,-0.19191900263943315,0.08159248636584522,1.0888371155747185,0.34393145728149,-0.3618795277123087,-0.5959301513849129,-0.4002819322572054,0.22282806736936095,-0.3618795277123087,-1.2455639283657367,-0.11782587038440924,-0.6358128758210178,-0.4002819322572054,-0.30471398246034614,-1.2234745726017855,-0.45833220142630116,-0.4778031665294185,0.3781227390966732,-0.32371131794603986,0.06371823925309218,-0.26689078457945037,-0.22929351713387358,-0.9225083508928148,-0.21057861160200061,0.4796375690603033,0.3781227390966732,1.3001107448304974,-0.556303522731768,-0.136268113638341,-0.3618795277123087,0.027819650621533694,-0.5365850315157712,-0.09943703415829816,0.27500609285862937,1.0734929151074688,0.00979464113285314,-0.2480641098102342,0.06371823925309218,-0.30471398246034614,1.2103624935934472,-0.2857739408302759,0.6780898876897556,-0.06281812401808029,0.34393145728149,3.341126344179749,0.29230599528747064,-0.3810512424874989,0.13491897416252877,-0.45833220142630116,-0.32371131794603986,-0.044587330503544284,-0.3810512424874989,-0.26689078457945037,-0.30471398246034614,-0.615839256133415,0.22282806736936095,0.2576600004388149,-0.0082812963420422,1.374016616607502,0.3267683908998871,0.06371823925309218,0.3267683908998871,-0.21057861160200061,2.046338095095178,-0.22929351713387358,0.2576600004388149,-0.615839256133415,1.0734929151074688,-0.8599277461978309,2.9143381717752534,0.49640508473295136,2.4617182325925935,0.04579407141593343,-0.5760850691049697,-0.2480641098102342,0.6125984519295641,0.027819650621533694,1.5768521422780388,-0.4002819322572054,0.7267883475768012,0.5796084169446801,-0.5760850691049697,0.027819650621533694,-0.30471398246034614,-0.3810512424874989,-0.30471398246034614,0.7911712365778563,2.9380359717002262,0.00979464113285314,0.11719253012638,0.06371823925309218,0.9651005639747406,-0.6961258399380261,1.1650436541393152,0.9023727529414285,-0.6558515089254989,1.2254023183728662,0.3095599986277176,4.911369288084267,0.9338096000880001,0.918109512811578,-0.8599277461978309,0.3267683908998871,0.2402674242042158,-0.5760850691049697,-0.136268113638341,-0.5760850691049697,-0.8185629381819824,-0.3427663604137081,4.883716386323005,-0.17331430397827757,1.3592986669267102,-0.556303522731768,-0.5959301513849129,-0.5959301513849129,1.4179833366718122,-0.2480641098102342,-0.2480641098102342,-0.45833220142630116,0.5796084169446801,-2.05120367646082,-0.9645911933381504,-0.4973353200537405,-0.17331430397827757,-0.4002819322572054,0.8390548805690391,-1.0069696246438355,1.5050886200820657,3.2281286571511263,0.8390548805690391,0.9962472414082676,1.2553833203983125
2,773
Nucleobase containing compound transmembrane transporter activity
10
13
2.549788
0.010779
Q6NUK1,Q9H2D1,P12235,P41440,O43808,Q8TB61,Q99808,Q9HC21,P12236,P51991
Functions
GO Molecular function
msigdb_gomf
346,71,295,171,457,144,378,350,536,611
653,1543,457,776,295,536,171,611,346,144,378,71,350
0.4459736330867459,-0.2480641098102342,0.7590573852352058,0.3095599986277176,1.1041467746508826,0.6125984519295641,1.591116683200521,0.5131299780208094,0.980691839776418,1.7182066280572748,0.9338096000880001,2.4364418134826944,0.980691839776418
2,773
Abnormal muscle fiber morphology
22
63
2.548648
0.010814
P00846,Q99720,P07196,P35609,Q70HW3,O95831,Q9Y4W6,O43676,P12235,Q9HA77,P50402,O14979,P22626,Q9H2D1,P61978,O60313,O75190,O96008,P23786,P00403,P35637,Q96RL7
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
1,264,383,136,12,278,555,34,295,564,433,190,320,71,201,458,466,353,97,227,118,252
929,190,34,1787,458,466,1751,278,353,227,1,993,2698,1357,383,2152,778,295,655,2156,320,97,2095,1098,136,118,1794,558,648,433,897,610,1653,2504,1334,201,1523,2637,1592,2164,2394,1701,2367,12,720,817,2112,1039,252,2624,264,1413,1163,2007,2740,71,564,1138,1821,1856,2596,555,1321
0.152596792346211,1.5195005799200332,3.0786729040592555,-0.3810512424874989,0.7590573852352058,0.7267883475768012,-0.3618795277123087,1.134663203113307,0.9651005639747406,1.344549265567791,5.209596006329733,0.09941714153263233,-1.448176424107011,-0.136268113638341,0.918109512811578,-0.5959301513849129,0.3095599986277176,1.1041467746508826,0.4459736330867459,-0.5959301513849129,1.0581139876819772,2.1128376187786273,-0.556303522731768,0.027819650621533694,1.787831714138425,1.9521881053380312,-0.3810512424874989,0.5796084169446801,0.4628271722565294,0.8231316615590936,0.18780780970224395,0.5131299780208094,-0.30471398246034614,-0.9435131294526775,-0.11782587038440924,1.4761747942022012,-0.22929351713387358,-1.1795408022055565,-0.26689078457945037,-0.5959301513849129,-0.7979854974629659,-0.32371131794603986,-0.7570377557857778,3.6057092764409786,0.3781227390966732,0.27500609285862937,-0.556303522731768,0.08159248636584522,1.2254023183728662,-1.1359288896386077,1.195289557247196,-0.15476413359326763,-0.0082812963420422,-0.4973353200537405,-1.9005752483061178,2.4364418134826944,0.5796084169446801,0.00979464113285314,-0.3810512424874989,-0.4002819322572054,-1.0711024232199626,0.5961239946346427,-0.09943703415829816
2,773
Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1
17
44
2.542656
0.011001
P28074,P28072,P49721,P53350,P49720,O00231,Q9UJX3,P28070,Q99436,P60900,Q96DE5,P25787,Q16763,P25789,Q9UJX2,P20618,P30260
Processes and pathways
Reactome Pathways
msigdb_reactome
321,263,70,548,296,491,566,142,600,302,207,81,594,301,382,279,415
491,2355,825,2049,827,1148,1096,279,1684,81,1290,301,931,142,263,321,415,2361,1518,609,296,70,1266,548,1694,302,783,852,870,1696,1697,801,1060,1061,594,1706,207,600,1881,382,566,972,1048,1711
0.6780898876897556,-0.7570377557857778,0.2576600004388149,-0.5365850315157712,0.2576600004388149,-0.0082812963420422,0.027819650621533694,1.134663203113307,-0.32371131794603986,2.3087285106625295,-0.09943703415829816,1.0888371155747185,0.152596792346211,1.7321867892631835,1.195289557247196,1.0581139876819772,0.8707883976495787,-0.7570377557857778,-0.22929351713387358,0.5131299780208094,1.1041467746508826,2.4364418134826944,-0.08110123928284446,0.5961239946346427,-0.32371131794603986,1.0888371155747185,0.3095599986277176,0.2402674242042158,0.22282806736936095,-0.32371131794603986,-0.32371131794603986,0.29230599528747064,0.06371823925309218,0.06371823925309218,0.5298125052139352,-0.32371131794603986,1.4471401018248031,0.5298125052139352,-0.41957202948870276,0.9338096000880001,0.5796084169446801,0.13491897416252877,0.08159248636584522,-0.32371131794603986
2,773
Underdeveloped supraorbital ridges
6
11
2.534828
0.01125
Q6NUK1,P98175,Q08J23,O75381,P50542,P16435
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
346,355,198,396,313,369
396,369,1211,635,313,1126,355,1339,198,346,437
0.9023727529414285,0.9338096000880001,-0.044587330503544284,0.4796375690603033,1.0734929151074688,0.00979464113285314,0.9651005639747406,-0.11782587038440924,1.4906467407975372,0.980691839776418,0.8231316615590936
2,773
Sterol metabolism
7
23
2.534405
0.011264
Q15392,P37268,Q15125,Q14739,O75845,Q16850,Q15800
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
99,38,74,76,143,120,187
283,143,1387,1754,633,1149,1448,590,38,2441,2214,2338,832,1058,2313,76,74,2070,99,901,187,120,2300
1.1194220763424934,1.7182066280572748,-0.15476413359326763,-0.3618795277123087,0.4796375690603033,-0.0082812963420422,-0.19191900263943315,0.5298125052139352,2.949856816516709,-0.8599277461978309,-0.6358128758210178,-0.7366663610142645,0.2576600004388149,0.06371823925309218,-0.7163625657538544,2.372865186563945,2.4237707360140495,-0.5365850315157712,2.099586937710835,0.18780780970224395,1.5338827670309567,1.9250582352755141,-0.6961258399380261
2,773
Synthesis of dna
26
79
2.529353
0.011427
Q9NR33,P28072,P28070,P20618,P30260,Q14566,P49720,Q9UBD5,Q9UJX3,P41440,P60900,P25789,Q9BRT9,P25205,P28074,P49721,Q9Y248,Q9Y619,Q99436,Q96DE5,P25787,Q16763,P33991,O00231,P49643,Q9UJX2
Processes and pathways
Reactome Pathways
msigdb_reactome
131,263,142,279,415,549,296,174,566,171,302,301,443,192,321,70,463,203,600,207,81,594,589,491,493,382
491,2355,825,2049,827,1637,1148,1208,2092,1869,1096,844,279,1391,192,1684,81,1290,301,1580,931,142,263,321,1514,415,589,1643,1644,1180,2534,2212,2334,2361,2652,1833,2024,171,1518,609,1101,493,296,70,981,1266,1694,302,783,852,870,1696,1337,1697,760,801,2067,963,549,1007,1060,1061,594,1706,207,600,1881,443,1375,131,174,382,566,972,1048,1711,463,1278,203
0.6780898876897556,-0.7570377557857778,0.2576600004388149,-0.5365850315157712,0.2576600004388149,-0.30471398246034614,-0.0082812963420422,-0.044587330503544284,-0.556303522731768,-0.41957202948870276,0.027819650621533694,0.2402674242042158,1.134663203113307,-0.15476413359326763,1.5195005799200332,-0.32371131794603986,2.3087285106625295,-0.09943703415829816,1.0888371155747185,-0.26689078457945037,0.152596792346211,1.7321867892631835,1.195289557247196,1.0581139876819772,-0.22929351713387358,0.8707883976495787,0.5298125052139352,-0.30471398246034614,-0.30471398246034614,-0.026408504701637636,-0.9857431524258583,-0.6358128758210178,-0.7366663610142645,-0.7570377557857778,-1.2234745726017855,-0.4002819322572054,-0.5169291204252513,1.591116683200521,-0.22929351713387358,0.5131299780208094,0.027819650621533694,0.6780898876897556,1.1041467746508826,2.4364418134826944,0.11719253012638,-0.08110123928284446,-0.32371131794603986,1.0888371155747185,0.3095599986277176,0.2402674242042158,0.22282806736936095,-0.32371131794603986,-0.11782587038440924,-0.32371131794603986,0.3267683908998871,0.29230599528747064,-0.5365850315157712,0.13491897416252877,0.5961239946346427,0.09941714153263233,0.06371823925309218,0.06371823925309218,0.5298125052139352,-0.32371131794603986,1.4471401018248031,0.5298125052139352,-0.41957202948870276,0.8071705185983409,-0.136268113638341,1.829279487006994,1.591116683200521,0.9338096000880001,0.5796084169446801,0.13491897416252877,0.08159248636584522,-0.32371131794603986,0.7590573852352058,-0.08110123928284446,1.4761747942022012
2,773
Ion homeostasis
39
88
2.526959
0.011505
P50897,Q9P246,P27361,Q7L0J3,Q15904,Q12955,P05023,Q9HD20,Q9Y487,Q8N511,Q9Y4W6,Q96A33,P09601,P04899,Q8TAD4,Q16891,P30519,P14625,Q96HE7,Q8NE86,P16615,Q93050,P06576,Q9Y5X3,P51790,P20020,Q8IYU8,Q96TC7,O95202,P62942,P28482,Q9UJZ1,O75027,Q8NE01,O75880,P35670,O75503,Q9Y639,O76024
Processes and pathways
GO Biological process
msigdb_gobp
129,392,262,139,525,660,397,29,163,35,555,160,285,284,168,421,43,674,177,694,300,53,431,584,447,455,460,599,341,220,354,630,233,626,615,249,499,255,367
1634,1635,1145,908,2424,233,499,615,2684,367,2407,341,1420,892,1992,284,397,431,2751,1896,1261,285,2128,2055,1289,674,300,1547,781,455,262,2654,2094,1685,354,43,1210,249,1360,1451,129,1053,1652,447,1722,758,2663,690,898,220,2492,1838,1427,833,660,1872,1592,1558,1367,2002,525,937,421,139,985,460,35,626,694,168,53,160,857,177,599,1413,2740,29,392,1575,1277,630,1320,163,555,584,255,2722
-0.30471398246034614,-0.30471398246034614,-0.0082812963420422,0.17022630011855963,-0.8392101662750319,1.3001107448304974,0.66177751226445,0.49640508473295136,-1.4025446082197535,0.9338096000880001,-0.8185629381819824,1.0117669641918954,-0.17331430397827757,0.18780780970224395,-0.4973353200537405,1.1194220763424934,0.9023727529414285,0.8231316615590936,-2.3651721003221735,-0.43892197167724356,-0.08110123928284446,1.1194220763424934,-0.5760850691049697,-0.5365850315157712,-0.09943703415829816,0.42907668779468716,1.0888371155747185,-0.2480641098102342,0.3095599986277176,0.7751335984561154,1.195289557247196,-1.2455639283657367,-0.556303522731768,-0.32371131794603986,0.9651005639747406,2.8667161497801694,-0.044587330503544284,1.2404092037293961,-0.136268113638341,-0.19191900263943315,1.8430416218620376,0.06371823925309218,-0.30471398246034614,0.7911712365778563,-0.3427663604137081,0.3267683908998871,-1.267735897113304,0.41213607006932595,0.18780780970224395,1.374016616607502,-0.9225083508928148,-0.4002819322572054,-0.17331430397827757,0.2576600004388149,0.4459736330867459,-0.41957202948870276,-0.26689078457945037,-0.2480641098102342,-0.136268113638341,-0.4973353200537405,0.6290320310309162,0.152596792346211,0.8549403888279615,1.760064137242113,0.11719253012638,0.7590573852352058,3.0786729040592555,0.49640508473295136,0.41213607006932595,1.6195587374943998,2.6731231556376405,1.66200633565837,0.2402674242042158,1.5768521422780388,0.5298125052139352,-0.15476413359326763,-1.9005752483061178,3.239504168358267,0.918109512811578,-0.2480641098102342,-0.08110123928284446,0.49640508473295136,-0.09943703415829816,1.66200633565837,0.5961239946346427,0.546452920177871,1.2254023183728662,-1.5638395884882637
2,773
Metal ion homeostasis
32
68
2.522465
0.011654
Q9P246,Q7L0J3,P05023,Q12955,Q15904,Q9HD20,Q9Y487,P09601,Q9Y4W6,P04899,Q8N511,Q96A33,Q16891,Q8TAD4,P30519,P14625,Q96HE7,Q8NE86,P16615,Q9Y5X3,P20020,Q8IYU8,Q96TC7,O95202,P62942,Q9UJZ1,O75027,Q8NE01,O75880,P35670,Q9Y639,O76024
Processes and pathways
GO Biological process
msigdb_gobp
392,139,397,660,525,29,163,285,555,284,35,160,421,168,43,674,177,694,300,584,455,460,599,341,220,630,233,626,615,249,255,367
1634,1635,908,2424,233,615,2684,367,341,1420,892,1992,284,397,2751,1896,1261,285,1289,674,300,1547,781,455,2654,2094,1685,43,1210,249,1360,1652,1722,758,2663,690,898,220,1838,1427,833,660,1872,1558,2002,525,937,421,139,985,460,35,626,694,168,160,177,599,1413,2740,29,392,630,1320,163,555,584,255
-0.30471398246034614,-0.30471398246034614,0.17022630011855963,-0.8392101662750319,1.3001107448304974,0.49640508473295136,-1.4025446082197535,0.9338096000880001,1.0117669641918954,-0.17331430397827757,0.18780780970224395,-0.4973353200537405,1.1194220763424934,0.9023727529414285,-2.3651721003221735,-0.43892197167724356,-0.08110123928284446,1.1194220763424934,-0.09943703415829816,0.42907668779468716,1.0888371155747185,-0.2480641098102342,0.3095599986277176,0.7751335984561154,-1.2455639283657367,-0.556303522731768,-0.32371131794603986,2.8667161497801694,-0.044587330503544284,1.2404092037293961,-0.136268113638341,-0.30471398246034614,-0.3427663604137081,0.3267683908998871,-1.267735897113304,0.41213607006932595,0.18780780970224395,1.374016616607502,-0.4002819322572054,-0.17331430397827757,0.2576600004388149,0.4459736330867459,-0.41957202948870276,-0.2480641098102342,-0.4973353200537405,0.6290320310309162,0.152596792346211,0.8549403888279615,1.760064137242113,0.11719253012638,0.7590573852352058,3.0786729040592555,0.49640508473295136,0.41213607006932595,1.6195587374943998,1.66200633565837,1.5768521422780388,0.5298125052139352,-0.15476413359326763,-1.9005752483061178,3.239504168358267,0.918109512811578,0.49640508473295136,-0.09943703415829816,1.66200633565837,0.5961239946346427,0.546452920177871,1.2254023183728662
2,773
Nucleotide transmembrane transporter activity
8
11
2.518724
0.011778
Q6NUK1,Q9H2D1,P12235,P41440,O43808,Q8TB61,Q99808,Q9HC21
Functions
GO Molecular function
msigdb_gomf
346,71,295,171,457,144,378,350
1543,457,776,295,536,171,346,144,378,71,350
-0.2480641098102342,0.7590573852352058,0.3095599986277176,1.1041467746508826,0.6125984519295641,1.591116683200521,0.980691839776418,1.7182066280572748,0.9338096000880001,2.4364418134826944,0.980691839776418
2,773
Organophosphate ester transmembrane transporter activity
8
11
2.518724
0.011778
Q6NUK1,Q9H2D1,P12235,P41440,O43808,Q8TB61,Q99808,Q9HC21
Functions
GO Molecular function
msigdb_gomf
346,71,295,171,457,144,378,350
1543,457,776,295,536,171,346,144,378,71,350
-0.2480641098102342,0.7590573852352058,0.3095599986277176,1.1041467746508826,0.6125984519295641,1.591116683200521,0.980691839776418,1.7182066280572748,0.9338096000880001,2.4364418134826944,0.980691839776418
2,773
Proteasome beta-type subunit, conserved site [IPR016050]
6
8
2.501628
0.012362
P28072,P49721,P49720,P28070,P25789,P20618
Sequence
InterPro Conserved site
interpro_conserved_site
263,70,296,142,301,279
279,301,142,263,321,296,70,600
1.134663203113307,1.0888371155747185,1.7321867892631835,1.195289557247196,1.0581139876819772,1.1041467746508826,2.4364418134826944,0.5298125052139352
2,773
Threonine type endopeptidase activity
6
8
2.501628
0.012362
P28072,P49721,P49720,P28070,P25789,P20618
Functions
GO Molecular function
msigdb_gomf
263,70,296,142,301,279
279,301,142,263,321,296,70,600
1.134663203113307,1.0888371155747185,1.7321867892631835,1.195289557247196,1.0581139876819772,1.1041467746508826,2.4364418134826944,0.5298125052139352
2,773
Metal ion transmembrane transporter activity
10
20
2.496205
0.012553
Q9P246,Q8IUH4,Q8TAD4,P05023,P16615,Q8N4V1,Q8N8Q9,O95202,P35670,Q9HD20
Functions
GO Molecular function
msigdb_gomf
392,103,168,397,300,61,409,341,249,29
341,397,2091,1896,647,300,455,249,2663,1213,1427,103,61,409,694,168,2498,29,392,1320
1.0117669641918954,0.9023727529414285,-0.556303522731768,-0.43892197167724356,0.4628271722565294,1.0888371155747185,0.7751335984561154,1.2404092037293961,-1.267735897113304,-0.044587330503544284,-0.17331430397827757,2.073011956873724,2.5992012852779514,0.8865991164842625,0.41213607006932595,1.6195587374943998,-0.9225083508928148,3.239504168358267,0.918109512811578,-0.09943703415829816
2,773
Protein processing
18
41
2.489129
0.012806
Q9NQH7,Q8TCT9,Q15392,Q9UG56,P67812,Q92542,Q99797,Q8TAD4,Q12797,P42892,Q5JRX3,Q96HE7,Q92896,Q96TA2,Q15005,O75844,O75503,Q10713
Processes and pathways
GO Biological process
msigdb_gobp
225,98,99,196,5,424,387,168,195,110,175,177,471,376,315,56,499,222
1891,1861,499,56,670,1287,2543,2628,2091,2128,1547,2720,1647,1032,1123,110,2748,1453,957,5,222,195,315,99,937,175,1530,1064,168,98,424,471,177,376,387,2348,1348,225,196,630,555
-0.43892197167724356,-0.41957202948870276,0.66177751226445,2.6608541324132817,0.42907668779468716,-0.09943703415829816,-1.0069696246438355,-1.1576949635950773,-0.556303522731768,-0.5760850691049697,-0.2480641098102342,-1.5638395884882637,-0.30471398246034614,0.08159248636584522,0.00979464113285314,2.006139977002886,-2.2585346900595407,-0.19191900263943315,0.13491897416252877,4.017298843354599,1.374016616607502,1.5050886200820657,1.0734929151074688,2.099586937710835,0.152596792346211,1.5768521422780388,-0.22929351713387358,0.06371823925309218,1.6195587374943998,2.1128376187786273,0.8549403888279615,0.7267883475768012,1.5768521422780388,0.9338096000880001,0.918109512811578,-0.7366663610142645,-0.11782587038440924,1.3592986669267102,1.5050886200820657,0.49640508473295136,0.5961239946346427
2,773
Mitochondrial calcium ion transport
10
15
2.485334
0.012943
P45880,Q9Y4W6,Q9UJZ1,Q8IYU8,Q9Y277,O95202,Q96TA2,Q99623,P21796,Q10713
Processes and pathways
Reactome Pathways
msigdb_reactome
64,555,630,460,169,341,376,377,155,222
1861,341,155,1392,64,222,460,694,1736,376,377,1413,630,169,555
-0.41957202948870276,1.0117669641918954,1.6901626766427875,-0.15476413359326763,2.5370280092342656,1.374016616607502,0.7590573852352058,0.41213607006932595,-0.3427663604137081,0.9338096000880001,0.9338096000880001,-0.15476413359326763,0.49640508473295136,1.6195587374943998,0.5961239946346427
2,773
Delusions
8
17
2.480999
0.013101
Q9UI10,Q9BQE5,Q9NZJ7,O43681,Q9UJS0,Q9NR50,P21964,Q96RL7
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
162,36,425,266,403,140,206,252
266,633,777,206,914,511,1394,1906,2314,1085,943,252,36,140,425,162,403
1.1650436541393152,0.4796375690603033,0.3095599986277176,1.4471401018248031,0.17022630011855963,0.6454249718956354,-0.15476413359326763,-0.43892197167724356,-0.7163625657538544,0.04579407141593343,0.152596792346211,1.2254023183728662,3.067053020828357,1.7461392490106311,0.8549403888279615,1.66200633565837,0.9023727529414285
2,773
Dna replication pre initiation
12
61
2.470483
0.013493
P25205,Q9NR33,P28072,P49721,P49720,Q9Y619,Q9UBD5,P28070,P60900,P25787,P25789,P20618
Processes and pathways
Reactome Pathways
msigdb_reactome
192,131,263,70,296,203,174,142,302,81,301,279
491,2355,825,2049,827,1826,1637,1148,1208,1869,2179,1096,279,1391,192,1684,81,1290,301,1580,931,142,263,321,589,1643,1644,1180,2361,1518,609,1101,493,296,70,981,1266,1614,1694,302,783,852,870,1696,2490,1697,760,801,963,549,834,1060,1061,1706,600,1881,131,174,1048,1711,203
0.6780898876897556,-0.7570377557857778,0.2576600004388149,-0.5365850315157712,0.2576600004388149,-0.4002819322572054,-0.30471398246034614,-0.0082812963420422,-0.044587330503544284,-0.41957202948870276,-0.615839256133415,0.027819650621533694,1.134663203113307,-0.15476413359326763,1.5195005799200332,-0.32371131794603986,2.3087285106625295,-0.09943703415829816,1.0888371155747185,-0.26689078457945037,0.152596792346211,1.7321867892631835,1.195289557247196,1.0581139876819772,0.5298125052139352,-0.30471398246034614,-0.30471398246034614,-0.026408504701637636,-0.7570377557857778,-0.22929351713387358,0.5131299780208094,0.027819650621533694,0.6780898876897556,1.1041467746508826,2.4364418134826944,0.11719253012638,-0.08110123928284446,-0.2857739408302759,-0.32371131794603986,1.0888371155747185,0.3095599986277176,0.2402674242042158,0.22282806736936095,-0.32371131794603986,-0.9225083508928148,-0.32371131794603986,0.3267683908998871,0.29230599528747064,0.13491897416252877,0.5961239946346427,0.2576600004388149,0.06371823925309218,0.06371823925309218,-0.32371131794603986,0.5298125052139352,-0.41957202948870276,1.829279487006994,1.591116683200521,0.08159248636584522,-0.32371131794603986,1.4761747942022012
2,773
Regulation of cellular ph
9
17
2.466854
0.013631
Q8N511,P51790,P50897,P28482,P27361,Q93050,P06576,O75503,Q9Y487
Processes and pathways
GO Biological process
msigdb_gobp
35,447,129,354,262,53,431,499,163
499,431,262,354,129,1053,447,690,1367,525,35,53,857,1575,1277,163,2722
0.66177751226445,0.8231316615590936,1.195289557247196,0.9651005639747406,1.8430416218620376,0.06371823925309218,0.7911712365778563,0.41213607006932595,-0.136268113638341,0.6290320310309162,3.0786729040592555,2.6731231556376405,0.2402674242042158,-0.2480641098102342,-0.08110123928284446,1.66200633565837,-1.5638395884882637
2,773
Regulation of ph
9
17
2.466854
0.013631
Q8N511,P51790,P50897,P28482,P27361,Q93050,P06576,O75503,Q9Y487
Processes and pathways
GO Biological process
msigdb_gobp
35,447,129,354,262,53,431,499,163
499,431,262,354,129,1053,447,690,1367,525,35,53,857,1575,1277,163,2722
0.66177751226445,0.8231316615590936,1.195289557247196,0.9651005639747406,1.8430416218620376,0.06371823925309218,0.7911712365778563,0.41213607006932595,-0.136268113638341,0.6290320310309162,3.0786729040592555,2.6731231556376405,0.2402674242042158,-0.2480641098102342,-0.08110123928284446,1.66200633565837,-1.5638395884882637
2,773
Nucleotide transport
8
12
2.465728
0.013673
Q6NUK1,Q9H2D1,P12235,P41440,O43808,Q8TB61,Q99808,Q9HC21
Processes and pathways
GO Biological process
msigdb_gobp
346,71,295,171,457,144,378,350
1543,457,776,295,536,171,691,346,144,378,71,350
-0.2480641098102342,0.7590573852352058,0.3095599986277176,1.1041467746508826,0.6125984519295641,1.591116683200521,0.41213607006932595,0.980691839776418,1.7182066280572748,0.9338096000880001,2.4364418134826944,0.980691839776418
2,773
Amyloid precursor protein catabolic process
8
16
2.46489
0.013706
Q15392,Q92542,Q96P70,O95197,P49755,P62942,Q16799,Q9NQC3
Processes and pathways
GO Biological process
msigdb_gobp
99,424,400,22,370,220,62,63
669,459,22,2654,1032,370,220,1872,2133,2000,99,62,424,400,1136,63
0.42907668779468716,0.7590573852352058,3.352334616639615,-1.2455639283657367,0.08159248636584522,0.9338096000880001,1.374016616607502,-0.41957202948870276,-0.5760850691049697,-0.4973353200537405,2.099586937710835,2.5868085972020687,0.8549403888279615,0.9023727529414285,0.00979464113285314,2.5619604388691277
2,773
Orc1 removal from chromatin
11
48
2.463749
0.013749
P25205,P28072,P49721,P49720,Q9Y619,Q9UBD5,P28070,P60900,P25787,P25789,P20618
Processes and pathways
Reactome Pathways
msigdb_reactome
192,263,70,296,203,174,142,302,81,301,279
491,2355,825,2049,827,1148,1096,279,1391,192,1684,81,1290,301,931,142,263,321,589,1643,1644,2361,1518,609,296,70,981,1266,1694,302,783,852,870,1696,1337,1697,801,2067,549,1060,1061,1706,600,1881,174,1048,1711,203
0.6780898876897556,-0.7570377557857778,0.2576600004388149,-0.5365850315157712,0.2576600004388149,-0.0082812963420422,0.027819650621533694,1.134663203113307,-0.15476413359326763,1.5195005799200332,-0.32371131794603986,2.3087285106625295,-0.09943703415829816,1.0888371155747185,0.152596792346211,1.7321867892631835,1.195289557247196,1.0581139876819772,0.5298125052139352,-0.30471398246034614,-0.30471398246034614,-0.7570377557857778,-0.22929351713387358,0.5131299780208094,1.1041467746508826,2.4364418134826944,0.11719253012638,-0.08110123928284446,-0.32371131794603986,1.0888371155747185,0.3095599986277176,0.2402674242042158,0.22282806736936095,-0.32371131794603986,-0.11782587038440924,-0.32371131794603986,0.29230599528747064,-0.5365850315157712,0.5961239946346427,0.06371823925309218,0.06371823925309218,-0.32371131794603986,0.5298125052139352,-0.41957202948870276,1.591116683200521,0.08159248636584522,-0.32371131794603986,1.4761747942022012
2,773
Proton transporting two sector atpase complex
13
22
2.461193
0.013848
P00846,Q8N511,P56385,Q9Y5K8,P36542,Q96IX5,Q15904,Q93050,P06576,P61421,O75964,P24539,Q9Y487
Localization
GO Cellular component
msigdb_gocc
1,35,322,631,712,695,525,53,431,690,122,730,163
728,122,1,431,997,2427,730,1549,712,932,1360,2671,1128,322,690,525,35,53,695,1277,163,631
0.36104948014525085,1.8978244995764642,5.209596006329733,0.8231316615590936,0.09941714153263233,-0.8392101662750319,0.36104948014525085,-0.2480641098102342,0.3781227390966732,0.152596792346211,-0.136268113638341,-1.289991216052848,0.00979464113285314,1.0581139876819772,0.41213607006932595,0.6290320310309162,3.0786729040592555,2.6731231556376405,0.41213607006932595,-0.08110123928284446,1.66200633565837,0.49640508473295136
2,773
Metal ion transport
22
87
2.456149
0.014043
Q9P246,P35609,P11413,P05023,Q8N8Q9,O15173,P21796,Q9HD20,P04899,Q8TAD4,Q96HE7,P16615,O75844,Q8N4V1,P20020,O95202,P62942,Q8IUH4,O75027,P46934,P35670,O76024
Processes and pathways
GO Biological process
msigdb_gobp
392,136,267,397,409,25,155,29,284,168,177,300,56,61,455,341,220,103,233,234,249,367
824,1145,2531,25,1026,697,2424,233,1028,1861,56,367,341,1957,892,284,397,1177,2091,1896,647,1898,267,1289,1716,300,1547,1958,781,455,2649,155,1391,2654,1685,1210,711,1292,1076,136,249,2025,234,846,897,1181,758,2663,798,2489,1213,898,220,1838,1427,1483,1242,1218,503,833,2101,1155,2364,660,1592,937,1460,103,985,460,61,409,694,168,2498,177,1413,2740,1196,29,392,1575,630,1320,2226,1172,555
0.2576600004388149,-0.0082812963420422,-0.9857431524258583,3.273528999551839,0.08159248636584522,0.3951515110109617,-0.8392101662750319,1.3001107448304974,0.08159248636584522,-0.41957202948870276,2.6608541324132817,0.9338096000880001,1.0117669641918954,-0.4778031665294185,0.18780780970224395,1.1194220763424934,0.9023727529414285,-0.026408504701637636,-0.556303522731768,-0.43892197167724356,0.4628271722565294,-0.43892197167724356,1.1650436541393152,-0.09943703415829816,-0.3427663604137081,1.0888371155747185,-0.2480641098102342,-0.4778031665294185,0.3095599986277176,0.7751335984561154,-1.2234745726017855,1.6901626766427875,-0.15476413359326763,-1.2455639283657367,-0.32371131794603986,-0.044587330503544284,0.3781227390966732,-0.09943703415829816,0.04579407141593343,1.787831714138425,1.2404092037293961,-0.5169291204252513,1.3001107448304974,0.2402674242042158,0.18780780970224395,-0.026408504701637636,0.3267683908998871,-1.267735897113304,0.29230599528747064,-0.9225083508928148,-0.044587330503544284,0.18780780970224395,1.374016616607502,-0.4002819322572054,-0.17331430397827757,-0.21057861160200061,-0.06281812401808029,-0.044587330503544284,0.66177751226445,0.2576600004388149,-0.556303522731768,-0.0082812963420422,-0.7570377557857778,0.4459736330867459,-0.26689078457945037,0.152596792346211,-0.19191900263943315,2.073011956873724,0.11719253012638,0.7590573852352058,2.5992012852779514,0.8865991164842625,0.41213607006932595,1.6195587374943998,-0.9225083508928148,1.5768521422780388,-0.15476413359326763,-1.9005752483061178,-0.026408504701637636,3.239504168358267,0.918109512811578,-0.2480641098102342,0.49640508473295136,-0.09943703415829816,-0.6358128758210178,-0.0082812963420422,0.5961239946346427
2,773
Protein transmembrane import into intracellular organelle
6
13
2.454181
0.014121
O60830,O96008,Q99595,O75381,P50542,O95831
Processes and pathways
GO Biological process
msigdb_gobp
0,353,2,396,313,278
406,727,0,396,775,278,353,2153,313,620,539,2,1743
0.8865991164842625,0.36104948014525085,5.280310292530859,0.9023727529414285,0.3095599986277176,1.134663203113307,0.9651005639747406,-0.5959301513849129,1.0734929151074688,0.49640508473295136,0.6125984519295641,4.911369288084267,-0.3427663604137081
2,773
Duplication involving bones of the feet
6
15
2.454132
0.014123
O43924,Q15125,Q14739,O75845,P21964,Q10713
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
10,74,76,143,206,222
10,143,341,586,206,2183,1766,222,2239,76,74,2320,1737,1628,1570
3.7983699214209543,1.7182066280572748,1.0117669641918954,0.5298125052139352,1.4471401018248031,-0.615839256133415,-0.3618795277123087,1.374016616607502,-0.6558515089254989,2.372865186563945,2.4237707360140495,-0.7163625657538544,-0.3427663604137081,-0.2857739408302759,-0.2480641098102342
2,773
Lipid droplet
10
31
2.453306
0.014155
P09455,Q99720,Q8N0X7,Q8NF37,Q9H6V9,Q8NBX0,Q07065,Q01105,O43760,Q96RL7
Localization
GO Cellular component
msigdb_gocc
294,264,426,427,44,75,211,218,124,252
2303,124,2277,1284,1545,1754,2089,2091,294,1238,1212,1053,1652,1334,218,211,2444,901,426,941,75,427,1086,1088,252,264,627,44,923,2013,452
-0.7163625657538544,1.8841683861125587,-0.6961258399380261,-0.09943703415829816,-0.2480641098102342,-0.3618795277123087,-0.556303522731768,-0.556303522731768,1.1041467746508826,-0.06281812401808029,-0.044587330503544284,0.06371823925309218,-0.30471398246034614,-0.11782587038440924,1.388703273348437,1.4179833366718122,-0.8599277461978309,0.18780780970224395,0.8390548805690391,0.152596792346211,2.4237707360140495,0.8390548805690391,0.04579407141593343,0.04579407141593343,1.2254023183728662,1.195289557247196,0.49640508473295136,2.854763055352524,0.17022630011855963,-0.4973353200537405,0.7911712365778563
2,773
Atpase coupled transmembrane transporter activity
11
22
2.451978
0.014207
P33527,P20020,Q9Y5K8,O75027,P05023,P16615,Q15388,P08183,P06576,P35670,Q9HD20
Functions
GO Molecular function
msigdb_gomf
166,455,631,233,397,300,620,368,431,249,29
1543,233,397,431,368,300,455,997,2427,829,166,249,932,1360,1363,690,1427,620,29,990,1277,631
-0.2480641098102342,1.3001107448304974,0.9023727529414285,0.8231316615590936,0.9338096000880001,1.0888371155747185,0.7751335984561154,0.09941714153263233,-0.8392101662750319,0.2576600004388149,1.6195587374943998,1.2404092037293961,0.152596792346211,-0.136268113638341,-0.136268113638341,0.41213607006932595,-0.17331430397827757,0.49640508473295136,3.239504168358267,0.11719253012638,-0.08110123928284446,0.49640508473295136
2,773
Membrane organization
62
202
2.440558
0.014665
Q9UH99,P50897,Q9NS69,O43681,Q9NX63,Q13505,Q8NHH9,Q5HYI7,Q3ZCQ8,Q9Y584,O15118,Q96A33,Q9Y4W6,O15258,Q9NZJ7,P33527,P12235,P53350,Q16891,Q15070,Q6UXV4,Q5XKP0,P41440,Q9Y5J9,Q8IXJ6,P16615,P07900,Q8IXI1,P50542,P50402,O75844,Q8N4V1,Q8N1F7,Q9NQC3,P45880,Q9UBV8,P51790,Q9P2W9,Q9UQB8,Q15629,Q9Y512,O14737,O60313,P31751,O95202,Q7L5D6,O75431,Q9Y5L4,Q86XL3,Q9NR31,Q14849,Q9BZG1,Q9P0J0,Q15392,P57088,P52789,Q9H3K2,Q9NPA0,P49755,O43760,P08183,Q9UNZ2
Processes and pathways
GO Biological process
msigdb_gobp
517,129,3,266,532,11,529,540,539,30,283,160,555,291,425,166,295,548,421,42,303,172,171,430,176,300,299,438,313,433,56,61,449,63,64,451,447,67,68,69,197,324,458,210,341,470,88,345,93,351,223,489,226,99,502,494,242,245,370,124,368,519
1986,1634,824,2327,1635,324,1145,864,1954,605,283,1475,291,1542,1676,1713,1119,266,124,1229,458,1283,2126,841,865,1751,992,88,1862,1286,56,1419,775,1507,1206,632,341,1991,1420,1029,1231,993,2486,1446,776,2091,299,1896,368,1789,1232,1829,295,300,1234,2393,845,1548,2572,1930,711,210,166,1687,1647,2589,171,2307,1934,64,2285,713,2025,1332,809,370,433,313,897,129,1053,2536,447,658,494,548,1766,1554,689,502,1453,1965,2603,2489,1213,1216,1768,1154,1427,1057,1429,812,1999,2747,833,1365,660,1806,763,637,1872,11,1402,1059,2000,1133,223,1367,639,42,2192,2002,1942,99,1459,69,937,421,539,677,1109,540,964,1080,2367,172,303,470,1811,93,595,1915,438,788,176,449,61,1946,940,2741,1494,529,1813,641,1086,1434,2290,160,1601,721,1374,2464,1163,2767,489,242,1921,245,63,351,2757,3,629,1436,532,704,425,1572,226,1783,1855,67,451,517,1575,565,2202,2014,1091,891,519,68,1856,2640,1473,2554,555,197,30,430,345,1255
-0.4973353200537405,-0.30471398246034614,0.2576600004388149,-0.7366663610142645,-0.30471398246034614,1.0427001461522951,-0.0082812963420422,0.22282806736936095,-0.4778031665294185,0.5131299780208094,1.1194220763424934,-0.21057861160200061,1.1041467746508826,-0.2480641098102342,-0.32371131794603986,-0.3427663604137081,0.00979464113285314,1.1650436541393152,1.8841683861125587,-0.06281812401808029,0.7590573852352058,-0.09943703415829816,-0.5760850691049697,0.2402674242042158,0.22282806736936095,-0.3618795277123087,0.09941714153263233,2.1918330750978643,-0.41957202948870276,-0.09943703415829816,2.6608541324132817,-0.17331430397827757,0.3095599986277176,-0.22929351713387358,-0.044587330503544284,0.4796375690603033,1.0117669641918954,-0.4973353200537405,-0.17331430397827757,0.08159248636584522,-0.06281812401808029,0.09941714153263233,-0.9225083508928148,-0.19191900263943315,0.3095599986277176,-0.556303522731768,1.0888371155747185,-0.43892197167724356,0.9338096000880001,-0.3810512424874989,-0.06281812401808029,-0.4002819322572054,1.1041467746508826,1.0888371155747185,-0.06281812401808029,-0.7979854974629659,0.2402674242042158,-0.2480641098102342,-1.049648621318993,-0.45833220142630116,0.3781227390966732,1.4179833366718122,1.6195587374943998,-0.32371131794603986,-0.30471398246034614,-1.0711024232199626,1.591116683200521,-0.7163625657538544,-0.45833220142630116,2.5370280092342656,-0.6961258399380261,0.3781227390966732,-0.5169291204252513,-0.11782587038440924,0.27500609285862937,0.9338096000880001,0.8231316615590936,1.0734929151074688,0.18780780970224395,1.8430416218620376,0.06371823925309218,-0.9857431524258583,0.7911712365778563,0.4459736330867459,0.6780898876897556,0.5961239946346427,-0.3618795277123087,-0.2480641098102342,0.41213607006932595,0.66177751226445,-0.19191900263943315,-0.4778031665294185,-1.0926332934479581,-0.9225083508928148,-0.044587330503544284,-0.044587330503544284,-0.3618795277123087,-0.0082812963420422,-0.17331430397827757,0.06371823925309218,-0.17331430397827757,0.27500609285862937,-0.4973353200537405,-2.1023206276155575,0.2576600004388149,-0.136268113638341,0.4459736330867459,-0.3810512424874989,0.3267683908998871,0.4796375690603033,-0.41957202948870276,3.6489374258930978,-0.15476413359326763,0.06371823925309218,-0.4973353200537405,0.00979464113285314,1.3592986669267102,-0.136268113638341,0.4796375690603033,2.9143381717752534,-0.615839256133415,-0.4973353200537405,-0.45833220142630116,2.099586937710835,-0.19191900263943315,2.4617182325925935,0.152596792346211,0.8549403888279615,0.6125984519295641,0.42907668779468716,0.027819650621533694,0.6125984519295641,0.13491897416252877,0.04579407141593343,-0.7570377557857778,1.591116683200521,1.0888371155747185,0.7267883475768012,-0.3810512424874989,2.1655974376673623,0.5298125052139352,-0.43892197167724356,0.8231316615590936,0.3095599986277176,1.5768521422780388,0.7911712365778563,2.5992012852779514,-0.45833220142630116,0.152596792346211,-1.9753880011110494,-0.21057861160200061,0.6290320310309162,-0.3810512424874989,0.4796375690603033,0.04579407141593343,-0.17331430397827757,-0.6961258399380261,1.66200633565837,-0.26689078457945037,0.3781227390966732,-0.136268113638341,-0.8807162496476115,-0.0082812963420422,-4.026912381506858,0.6943623315630637,1.2703248377219385,-0.43892197167724356,1.2553833203983125,2.5619604388691277,0.980691839776418,-3.1456212575413347,4.883716386323005,0.49640508473295136,-0.17331430397827757,0.6290320310309162,0.3951515110109617,0.8549403888279615,-0.2480641098102342,1.3592986669267102,-0.3618795277123087,-0.4002819322572054,2.499469862693214,0.7911712365778563,0.6454249718956354,-0.2480641098102342,0.5796084169446801,-0.615839256133415,-0.4973353200537405,0.04579407141593343,0.20534163014615786,0.6454249718956354,2.486907600894611,-0.4002819322572054,-1.1795408022055565,-0.19191900263943315,-1.0069696246438355,0.5961239946346427,1.5050886200820657,3.2281286571511263,0.8390548805690391,0.9962472414082676,-0.06281812401808029
2,773
Passive transmembrane transporter activity
12
30
2.433532
0.014952
P45880,P00846,P56385,O96008,Q9P246,Q99797,Q9Y277,Q9C0H2,P06576,Q9BVC6,O75964,P21796
Functions
GO Molecular function
msigdb_gomf
64,1,322,353,392,387,169,276,431,317,122,155
2450,728,122,353,1,431,2091,1896,155,730,1549,712,1360,64,2671,447,1363,1128,322,1213,833,694,2498,387,317,276,392,1320,169,2722
-0.8807162496476115,0.36104948014525085,1.8978244995764642,0.9651005639747406,5.209596006329733,0.8231316615590936,-0.556303522731768,-0.43892197167724356,1.6901626766427875,0.36104948014525085,-0.2480641098102342,0.3781227390966732,-0.136268113638341,2.5370280092342656,-1.289991216052848,0.7911712365778563,-0.136268113638341,0.00979464113285314,1.0581139876819772,-0.044587330503544284,0.2576600004388149,0.41213607006932595,-0.9225083508928148,0.918109512811578,1.0734929151074688,1.1498703359019637,0.918109512811578,-0.09943703415829816,1.6195587374943998,-1.5638395884882637
2,773
Abnormal circulating lipid concentration
21
66
2.432394
0.014999
Q9UJS0,P28070,O75845,O75381,Q8N511,Q9NZJ7,P37268,P50542,O75844,Q15800,O43772,Q15125,O95470,Q14739,Q8NFG4,P31751,O75431,P23786,Q15392,P51659,Q9NVI7
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
403,142,143,396,35,425,38,313,56,187,191,74,204,76,338,210,88,97,99,361,381
1204,1026,191,396,88,56,143,615,204,993,2090,994,777,1927,2749,998,97,142,1514,210,2454,2212,2096,2360,38,2770,635,1648,2098,1362,2263,433,313,2573,361,1900,2186,797,2235,1999,733,1102,1103,1592,76,746,74,99,901,187,525,572,765,35,338,1039,1434,2658,1163,1537,381,425,2405,403,1169,1228
-0.044587330503544284,0.08159248636584522,1.5195005799200332,0.9023727529414285,2.1918330750978643,2.6608541324132817,1.7182066280572748,0.49640508473295136,1.4616726312748283,0.09941714153263233,-0.556303522731768,0.09941714153263233,0.3095599986277176,-0.45833220142630116,-2.3115963538256112,0.09941714153263233,2.1128376187786273,1.7321867892631835,-0.22929351713387358,1.4179833366718122,-0.8807162496476115,-0.6358128758210178,-0.556303522731768,-0.7570377557857778,2.949856816516709,-6.140695862452927,0.4796375690603033,-0.30471398246034614,-0.556303522731768,-0.136268113638341,-0.6759556600324522,0.8231316615590936,1.0734929151074688,-1.049648621318993,0.9494732169881561,-0.43892197167724356,-0.615839256133415,0.29230599528747064,-0.6558515089254989,-0.4973353200537405,0.36104948014525085,0.027819650621533694,0.027819650621533694,-0.26689078457945037,2.372865186563945,0.34393145728149,2.4237707360140495,2.099586937710835,0.18780780970224395,1.5338827670309567,0.6290320310309162,0.5630514743848866,0.3267683908998871,3.0786729040592555,1.027251201775276,0.08159248636584522,-0.17331430397827757,-1.2455639283657367,-0.0082812963420422,-0.22929351713387358,0.9338096000880001,0.8549403888279615,-0.7979854974629659,0.9023727529414285,-0.0082812963420422,-0.044587330503544284
2,773
Nucleotide-binding alpha-beta plait domain superfamily [IPR012677]
37
116
2.430157
0.015092
Q9Y6M1,O43390,Q8WXF1,P26368,Q14011,Q99729,Q96E39,Q96PK6,P43243,P31943,Q13595,O60506,O14979,Q13151,P22626,P55795,P23246,Q9BWF3,Q07955,Q01085,P38159,P98179,Q13242,P51991,Q15233,P98175,P52597,Q14103,Q01844,Q76FK4,Q9UHX1,P23588,P62995,Q92804,P35637,P07910,P31942
Sequence
InterPro Superfamily
interpro_homologous_superfamily
520,261,386,268,148,156,419,552,558,181,442,185,190,570,320,328,336,474,591,468,217,221,477,611,478,355,232,362,236,624,239,359,244,119,118,500,125
1416,190,2123,261,1677,185,795,1544,2485,1120,1509,500,2545,1260,2232,778,698,1390,1074,1330,320,336,359,268,1423,1098,125,181,1075,118,217,2097,558,1799,611,850,232,328,1127,1335,244,831,355,221,2064,468,236,2673,591,814,763,570,477,2163,1366,1035,1525,442,148,362,2508,2001,2414,1106,746,478,1107,2395,785,1079,621,902,2340,2525,624,817,1598,1668,2004,1493,939,1134,1084,1188,2369,386,1112,119,836,419,989,1602,552,944,1628,156,474,1741,1850,1671,968,773,1198,2373,1470,1923,2432,1573,239,861,1985,2433,1473,1442,1173,520
-0.17331430397827757,1.5195005799200332,-0.5760850691049697,1.195289557247196,-0.32371131794603986,1.5338827670309567,0.29230599528747064,-0.2480641098102342,-0.9225083508928148,0.00979464113285314,-0.22929351713387358,0.66177751226445,-1.0069696246438355,-0.08110123928284446,-0.6558515089254989,0.3095599986277176,0.3951515110109617,-0.15476413359326763,0.04579407141593343,-0.11782587038440924,1.0581139876819772,1.027251201775276,0.9494732169881561,1.1650436541393152,-0.17331430397827757,0.027819650621533694,1.8841683861125587,1.548235327001688,0.04579407141593343,1.9521881053380312,1.388703273348437,-0.556303522731768,0.5796084169446801,-0.3810512424874989,0.5131299780208094,0.2402674242042158,1.314955466473564,1.0427001461522951,0.00979464113285314,-0.11782587038440924,1.2553833203983125,0.2576600004388149,0.9651005639747406,1.374016616607502,-0.5365850315157712,0.7267883475768012,1.2852339236651187,-1.289991216052848,0.5298125052139352,0.27500609285862937,0.3267683908998871,0.5630514743848866,0.7105950751419811,-0.5959301513849129,-0.136268113638341,0.08159248636584522,-0.22929351713387358,0.8071705185983409,1.7041986344809297,0.9494732169881561,-0.9435131294526775,-0.4973353200537405,-0.8185629381819824,0.027819650621533694,0.34393145728149,0.7105950751419811,0.027819650621533694,-0.7979854974629659,0.3095599986277176,0.04579407141593343,0.49640508473295136,0.18780780970224395,-0.7366663610142645,-0.9645911933381504,0.49640508473295136,0.27500609285862937,-0.26689078457945037,-0.30471398246034614,-0.4973353200537405,-0.21057861160200061,0.152596792346211,0.00979464113285314,0.04579407141593343,-0.026408504701637636,-0.7570377557857778,0.918109512811578,0.027819650621533694,1.9521881053380312,0.2576600004388149,0.8707883976495787,0.11719253012638,-0.26689078457945037,0.5961239946346427,0.152596792346211,-0.2857739408302759,1.6901626766427875,0.7267883475768012,-0.3427663604137081,-0.4002819322572054,-0.30471398246034614,0.13491897416252877,0.3267683908998871,-0.026408504701637636,-0.7570377557857778,-0.19191900263943315,-0.43892197167724356,-0.8392101662750319,-0.2480641098102342,1.2852339236651187,0.2402674242042158,-0.4778031665294185,-0.8392101662750319,-0.19191900263943315,-0.17331430397827757,-0.0082812963420422,0.6454249718956354
2,773
RNA recognition motif domain [IPR000504]
37
108
2.428379
0.015166
Q9Y6M1,O43390,Q8WXF1,P26368,Q14011,Q99729,Q96E39,Q96PK6,P43243,P31943,Q13595,O60506,O14979,Q13151,P22626,P55795,P23246,Q9BWF3,Q07955,Q01085,P38159,P98179,Q13242,P51991,Q15233,P98175,P52597,Q14103,Q01844,Q76FK4,Q9UHX1,P23588,P62995,Q92804,P35637,P07910,P31942
Sequence
InterPro Domain
interpro_domain
520,261,386,268,148,156,419,552,558,181,442,185,190,570,320,328,336,474,591,468,217,221,477,611,478,355,232,362,236,624,239,359,244,119,118,500,125
1416,190,2123,261,1677,185,795,1544,2485,1509,500,2545,1260,2232,778,698,1390,1074,1330,320,336,359,268,1423,1098,125,181,1075,118,217,2097,558,1799,611,850,232,328,1127,244,831,355,221,2064,468,236,2673,591,814,763,570,477,2163,1366,1035,1525,442,148,362,2508,2001,2414,1106,746,478,1107,2395,785,1079,621,902,2340,2525,624,817,1598,1668,2004,1493,939,1084,1188,2369,386,119,836,419,989,1602,552,944,1628,156,474,1741,1850,968,773,1198,2373,1470,1923,2432,239,861,2433,1442,1173,520
-0.17331430397827757,1.5195005799200332,-0.5760850691049697,1.195289557247196,-0.32371131794603986,1.5338827670309567,0.29230599528747064,-0.2480641098102342,-0.9225083508928148,-0.22929351713387358,0.66177751226445,-1.0069696246438355,-0.08110123928284446,-0.6558515089254989,0.3095599986277176,0.3951515110109617,-0.15476413359326763,0.04579407141593343,-0.11782587038440924,1.0581139876819772,1.027251201775276,0.9494732169881561,1.1650436541393152,-0.17331430397827757,0.027819650621533694,1.8841683861125587,1.548235327001688,0.04579407141593343,1.9521881053380312,1.388703273348437,-0.556303522731768,0.5796084169446801,-0.3810512424874989,0.5131299780208094,0.2402674242042158,1.314955466473564,1.0427001461522951,0.00979464113285314,1.2553833203983125,0.2576600004388149,0.9651005639747406,1.374016616607502,-0.5365850315157712,0.7267883475768012,1.2852339236651187,-1.289991216052848,0.5298125052139352,0.27500609285862937,0.3267683908998871,0.5630514743848866,0.7105950751419811,-0.5959301513849129,-0.136268113638341,0.08159248636584522,-0.22929351713387358,0.8071705185983409,1.7041986344809297,0.9494732169881561,-0.9435131294526775,-0.4973353200537405,-0.8185629381819824,0.027819650621533694,0.34393145728149,0.7105950751419811,0.027819650621533694,-0.7979854974629659,0.3095599986277176,0.04579407141593343,0.49640508473295136,0.18780780970224395,-0.7366663610142645,-0.9645911933381504,0.49640508473295136,0.27500609285862937,-0.26689078457945037,-0.30471398246034614,-0.4973353200537405,-0.21057861160200061,0.152596792346211,0.04579407141593343,-0.026408504701637636,-0.7570377557857778,0.918109512811578,1.9521881053380312,0.2576600004388149,0.8707883976495787,0.11719253012638,-0.26689078457945037,0.5961239946346427,0.152596792346211,-0.2857739408302759,1.6901626766427875,0.7267883475768012,-0.3427663604137081,-0.4002819322572054,0.13491897416252877,0.3267683908998871,-0.026408504701637636,-0.7570377557857778,-0.19191900263943315,-0.43892197167724356,-0.8392101662750319,1.2852339236651187,0.2402674242042158,-0.8392101662750319,-0.17331430397827757,-0.0082812963420422,0.6454249718956354
2,773
Endoplasmic reticulum organization
14
41
2.425823
0.015274
Q96A33,Q9NXE4,Q9P2W9,Q15629,O15027,O43681,Q8NHH9,Q9NPA0,P50542,O95197,Q7L5D6,P57088,Q8N4V1,Q9NQC3
Processes and pathways
GO Biological process
msigdb_gobp
160,554,67,69,605,266,529,245,313,22,470,502,61,63
753,2434,824,1954,605,1713,266,1229,1206,22,1420,713,1362,313,502,1695,1213,1429,899,1806,639,2444,1942,69,964,1080,470,61,940,1494,529,160,1191,2420,923,245,63,554,1783,67,1255
0.3267683908998871,-0.8599277461978309,0.2576600004388149,-0.4778031665294185,0.5131299780208094,-0.3427663604137081,1.1650436541393152,-0.06281812401808029,-0.044587330503544284,3.352334616639615,-0.17331430397827757,0.3781227390966732,-0.136268113638341,1.0734929151074688,0.66177751226445,-0.32371131794603986,-0.044587330503544284,-0.17331430397827757,0.18780780970224395,-0.3810512424874989,0.4796375690603033,-0.8599277461978309,-0.45833220142630116,2.4617182325925935,0.13491897416252877,0.04579407141593343,0.7267883475768012,2.5992012852779514,0.152596792346211,-0.21057861160200061,0.6290320310309162,1.66200633565837,-0.026408504701637636,-0.8185629381819824,0.17022630011855963,1.2553833203983125,2.5619604388691277,0.5961239946346427,-0.3618795277123087,2.499469862693214,-0.06281812401808029
2,773
Peptide binding
19
66
2.420037
0.015519
P52292,Q9H7Z7,P24390,P10321,Q92973,P55786,O00410,Q9Y584,P50542,O15212,O00264,Q9BYT8,Q9UIQ6,O14787,Q8WTV0,Q15392,Q9NZ08,O14773,P42892
Functions
GO Molecular function
msigdb_gomf
257,389,6,384,271,23,405,30,313,440,87,219,352,476,94,99,108,492,110
87,405,874,492,476,440,2584,654,1826,775,646,509,2257,740,673,384,1389,2725,2600,6,2094,1685,2572,2636,2438,1051,1583,635,110,2159,2059,1295,313,257,1614,1239,23,1937,1213,1521,1055,1155,1725,1872,834,2190,620,99,623,986,94,271,1601,945,1314,2144,219,2200,389,1022,108,1574,1199,352,927,30
2.2179736349774104,0.8865991164842625,0.20534163014615786,0.6780898876897556,0.7105950751419811,0.8071705185983409,-1.0711024232199626,0.4459736330867459,-0.4002819322572054,0.3095599986277176,0.4628271722565294,0.6454249718956354,-0.6759556600324522,0.34393145728149,0.42907668779468716,0.918109512811578,-0.15476413359326763,-1.6107564567697954,-1.0926332934479581,3.9863939504190715,-0.556303522731768,-0.32371131794603986,-1.049648621318993,-1.1795408022055565,-0.8599277461978309,0.06371823925309218,-0.26689078457945037,0.4796375690603033,2.006139977002886,-0.5959301513849129,-0.5365850315157712,-0.09943703415829816,1.0734929151074688,1.2103624935934472,-0.2857739408302759,-0.06281812401808029,3.341126344179749,-0.45833220142630116,-0.044587330503544284,-0.22929351713387358,0.06371823925309218,-0.0082812963420422,-0.3427663604137081,-0.41957202948870276,0.2576600004388149,-0.615839256133415,0.49640508473295136,2.099586937710835,0.49640508473295136,0.11719253012638,2.1655974376673623,1.1650436541393152,-0.26689078457945037,0.152596792346211,-0.09943703415829816,-0.5760850691049697,1.388703273348437,-0.615839256133415,0.918109512811578,0.09941714153263233,2.046338095095178,-0.2480641098102342,-0.026408504701637636,0.980691839776418,0.17022630011855963,3.2281286571511263
2,773
Fad binding
7
9
2.416071
0.015689
Q15392,O00116,O15254,Q96HE7,Q8NB78,O95831,Q15067
Functions
GO Molecular function
msigdb_gomf
99,481,111,177,274,278,186
481,111,278,1754,496,186,99,274,177
0.6943623315630637,1.9926902049699322,1.134663203113307,-0.3618795277123087,0.6780898876897556,1.5338827670309567,2.099586937710835,1.1498703359019637,1.5768521422780388
2,773
Steroid metabolism
8
25
2.41249
0.015844
Q15392,P37268,Q15125,Q14739,O75845,Q16850,Q15800,O15118
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
99,38,74,76,143,120,187,283
283,143,1387,1754,633,1149,1448,590,38,2441,2214,2338,832,329,1058,2313,76,74,2070,99,901,187,120,2578,2300
1.1194220763424934,1.7182066280572748,-0.15476413359326763,-0.3618795277123087,0.4796375690603033,-0.0082812963420422,-0.19191900263943315,0.5298125052139352,2.949856816516709,-0.8599277461978309,-0.6358128758210178,-0.7366663610142645,0.2576600004388149,1.0427001461522951,0.06371823925309218,-0.7163625657538544,2.372865186563945,2.4237707360140495,-0.5365850315157712,2.099586937710835,0.18780780970224395,1.5338827670309567,1.9250582352755141,-1.049648621318993,-0.6961258399380261
2,773
Protein localization to endoplasmic reticulum
8
32
2.4116
0.015883
O15258,Q15629,P24390,O43681,Q9Y5M8,Q9UGP8,Q96HY6,Q9NQC3
Processes and pathways
GO Biological process
msigdb_gobp
291,69,6,266,246,214,250,63
605,291,687,266,1229,2051,1756,2154,6,1583,713,1100,1652,1800,1902,957,1937,1695,1213,315,2444,69,1080,470,1086,250,2420,63,1783,214,1574,246
0.5131299780208094,1.1041467746508826,0.41213607006932595,1.1650436541393152,-0.06281812401808029,-0.5365850315157712,-0.3618795277123087,-0.5959301513849129,3.9863939504190715,-0.26689078457945037,0.3781227390966732,0.027819650621533694,-0.30471398246034614,-0.3810512424874989,-0.43892197167724356,0.13491897416252877,-0.45833220142630116,-0.32371131794603986,-0.044587330503544284,1.0734929151074688,-0.8599277461978309,2.4617182325925935,0.04579407141593343,0.7267883475768012,0.04579407141593343,1.2404092037293961,-0.8185629381819824,2.5619604388691277,-0.3618795277123087,1.4179833366718122,-0.2480641098102342,1.2553833203983125
2,773
Regulation of hmox1 expression and activity
10
44
2.40953
0.015973
P09601,Q8TCT9,P28072,P49721,P49720,P28070,P60900,P25787,P25789,P20618
Processes and pathways
Reactome Pathways
msigdb_reactome
285,98,263,70,296,142,302,81,301,279
491,2355,825,2049,827,1148,285,1096,1832,279,1684,81,1290,301,931,142,263,321,2361,1518,609,296,70,1266,1694,302,783,852,870,1696,1337,1426,1697,801,2067,1402,1060,1061,98,1706,600,1881,1048,1711
0.6780898876897556,-0.7570377557857778,0.2576600004388149,-0.5365850315157712,0.2576600004388149,-0.0082812963420422,1.1194220763424934,0.027819650621533694,-0.4002819322572054,1.134663203113307,-0.32371131794603986,2.3087285106625295,-0.09943703415829816,1.0888371155747185,0.152596792346211,1.7321867892631835,1.195289557247196,1.0581139876819772,-0.7570377557857778,-0.22929351713387358,0.5131299780208094,1.1041467746508826,2.4364418134826944,-0.08110123928284446,-0.32371131794603986,1.0888371155747185,0.3095599986277176,0.2402674242042158,0.22282806736936095,-0.32371131794603986,-0.11782587038440924,-0.17331430397827757,-0.32371131794603986,0.29230599528747064,-0.5365850315157712,-0.15476413359326763,0.06371823925309218,0.06371823925309218,2.1128376187786273,-0.32371131794603986,0.5298125052139352,-0.41957202948870276,0.08159248636584522,-0.32371131794603986
2,773
Translocase
10
22
2.399576
0.016414
P00403,Q8NBU5,P33527,P05023,P16615,P08183,P06576,P35670,Q13423,Q9HD20
Functions
Protein Atlas Molecular function
protein_atlas_molecular_function
227,423,166,397,300,368,431,249,92,29
1543,1636,1385,1176,227,397,431,368,557,300,2260,455,2306,166,249,1360,757,2677,1427,92,423,29
-0.2480641098102342,-0.30471398246034614,-0.15476413359326763,-0.026408504701637636,1.344549265567791,0.9023727529414285,0.8231316615590936,0.9338096000880001,0.5796084169446801,1.0888371155747185,-0.6759556600324522,0.7751335984561154,-0.7163625657538544,1.6195587374943998,1.2404092037293961,-0.136268113638341,0.3267683908998871,-1.3347549057430848,-0.17331430397827757,2.1655974376673623,0.8549403888279615,3.239504168358267
2,773
Apc c mediated degradation of cell cycle proteins
18
50
2.393565
0.016686
P28074,P28072,P49721,P53350,P49720,P14635,O00231,Q9UJX3,P28070,Q99436,P60900,Q96DE5,P25787,Q16763,P25789,Q9UJX2,P20618,P30260
Processes and pathways
Reactome Pathways
msigdb_reactome
321,263,70,548,296,546,491,566,142,600,302,207,81,594,301,382,279,415
491,2355,825,2049,827,2472,1148,1031,546,1096,279,1391,1684,81,1290,301,931,142,263,321,415,2361,1518,609,296,70,1266,548,1694,302,783,852,870,1696,1337,1697,801,2067,1060,1061,594,1706,207,600,1881,382,566,972,1048,1711
0.6780898876897556,-0.7570377557857778,0.2576600004388149,-0.5365850315157712,0.2576600004388149,-0.9015762556906748,-0.0082812963420422,0.08159248636584522,0.5961239946346427,0.027819650621533694,1.134663203113307,-0.15476413359326763,-0.32371131794603986,2.3087285106625295,-0.09943703415829816,1.0888371155747185,0.152596792346211,1.7321867892631835,1.195289557247196,1.0581139876819772,0.8707883976495787,-0.7570377557857778,-0.22929351713387358,0.5131299780208094,1.1041467746508826,2.4364418134826944,-0.08110123928284446,0.5961239946346427,-0.32371131794603986,1.0888371155747185,0.3095599986277176,0.2402674242042158,0.22282806736936095,-0.32371131794603986,-0.11782587038440924,-0.32371131794603986,0.29230599528747064,-0.5365850315157712,0.06371823925309218,0.06371823925309218,0.5298125052139352,-0.32371131794603986,1.4471401018248031,0.5298125052139352,-0.41957202948870276,0.9338096000880001,0.5796084169446801,0.13491897416252877,0.08159248636584522,-0.32371131794603986
2,773
Proton transmembrane transport
12
42
2.390757
0.016814
P00846,P13073,P56385,P00403,P12235,Q8TAD4,P05023,Q9UDW1,P06576,Q99623,O75964,Q13423
Processes and pathways
GO Biological process
msigdb_gobp
1,130,322,227,295,168,397,52,431,377,122,92
929,1145,1026,1636,728,122,227,1,397,776,431,557,1388,295,130,501,997,2427,730,1549,2572,1099,712,932,1360,757,2671,447,1128,322,690,1131,92,168,2709,377,1849,946,52,1575,1277,630
0.152596792346211,-0.0082812963420422,0.08159248636584522,-0.30471398246034614,0.36104948014525085,1.8978244995764642,1.344549265567791,5.209596006329733,0.9023727529414285,0.3095599986277176,0.8231316615590936,0.5796084169446801,-0.15476413359326763,1.1041467746508826,1.829279487006994,0.66177751226445,0.09941714153263233,-0.8392101662750319,0.36104948014525085,-0.2480641098102342,-1.049648621318993,0.027819650621533694,0.3781227390966732,0.152596792346211,-0.136268113638341,0.3267683908998871,-1.289991216052848,0.7911712365778563,0.00979464113285314,1.0581139876819772,0.41213607006932595,0.00979464113285314,2.1655974376673623,1.6195587374943998,-1.4941668178214311,0.9338096000880001,-0.4002819322572054,0.152596792346211,2.721996774098279,-0.2480641098102342,-0.08110123928284446,0.49640508473295136
2,773
Secondary alcohol metabolic process
13
41
2.390247
0.016837
Q14849,Q06520,Q9BQE5,Q15392,P37268,Q15125,P11413,Q14739,O75845,Q16850,Q15800,Q8WTV0,O15118
Processes and pathways
GO Biological process
msigdb_gobp
223,329,36,99,38,74,267,76,143,120,187,94,283
283,2177,143,774,1387,1754,633,267,1149,369,1448,2454,590,38,2307,1238,796,2263,2705,1963,955,2441,2214,2338,832,329,1058,2313,496,76,223,74,2070,99,901,187,120,94,2659,36,2300
1.1194220763424934,-0.615839256133415,1.7182066280572748,0.3095599986277176,-0.15476413359326763,-0.3618795277123087,0.4796375690603033,1.1650436541393152,-0.0082812963420422,0.9338096000880001,-0.19191900263943315,-0.8807162496476115,0.5298125052139352,2.949856816516709,-0.7163625657538544,-0.06281812401808029,0.29230599528747064,-0.6759556600324522,-1.4711263808025372,-0.4778031665294185,0.13491897416252877,-0.8599277461978309,-0.6358128758210178,-0.7366663610142645,0.2576600004388149,1.0427001461522951,0.06371823925309218,-0.7163625657538544,0.6780898876897556,2.372865186563945,1.3592986669267102,2.4237707360140495,-0.5365850315157712,2.099586937710835,0.18780780970224395,1.5338827670309567,1.9250582352755141,2.1655974376673623,-1.2455639283657367,3.067053020828357,-0.6961258399380261
2,773
Localization within membrane
39
160
2.389835
0.016856
Q9NS69,Q9BTX1,P35609,O43681,P43307,Q9HD20,Q9Y584,O15118,Q96A33,O15258,Q8NBU5,Q9NZJ7,Q86YV9,Q15070,P41440,Q99805,Q9Y5J9,P07900,P50542,Q14168,Q8N4V1,Q15057,Q9Y512,O75915,Q15629,Q9HD45,O14737,P31751,Q9UGP8,O00264,Q7L5D6,Q9Y5L4,Q96KP1,Q9BZG1,Q9P0J0,Q96A65,O60725,Q9NPA0,Q9Y4G8
Processes and pathways
GO Biological process
msigdb_gobp
3,133,136,266,28,29,30,283,160,291,423,425,422,42,171,306,430,299,313,183,61,448,197,446,69,72,324,210,214,87,470,345,96,489,226,488,102,245,254
2354,1634,87,1987,2608,1635,324,1145,864,1954,605,283,291,1542,1713,266,1229,2126,102,669,1750,2519,1476,1286,446,1419,2051,775,483,1545,1177,777,299,1756,2653,1328,1958,952,2649,1930,2182,711,210,1292,1687,1646,136,656,2183,1583,635,1552,171,28,2285,713,2025,809,1100,313,897,1053,2536,758,2337,830,1240,1800,1453,2603,1937,1695,869,1213,1768,1055,2492,1154,1427,1483,812,833,2101,1365,660,1872,1527,183,2000,1528,1133,639,2444,448,42,983,2002,1942,1459,69,525,622,1307,1109,964,2341,470,562,1915,422,1667,61,940,423,2741,2111,2290,160,488,1847,1601,721,96,789,1068,306,133,489,2146,2420,627,29,2540,72,245,1570,3,1983,425,226,1168,214,1574,1575,518,2080,2014,891,906,1353,1856,2640,2554,1141,254,197,30,430,345,1144
-0.7570377557857778,-0.30471398246034614,2.2179736349774104,-0.4973353200537405,-1.1142418924464381,-0.30471398246034614,1.0427001461522951,-0.0082812963420422,0.22282806736936095,-0.4778031665294185,0.5131299780208094,1.1194220763424934,1.1041467746508826,-0.2480641098102342,-0.3427663604137081,1.1650436541393152,-0.06281812401808029,-0.5760850691049697,2.073011956873724,0.42907668779468716,-0.3618795277123087,-0.9645911933381504,-0.21057861160200061,-0.09943703415829816,0.7911712365778563,-0.17331430397827757,-0.5365850315157712,0.3095599986277176,0.6943623315630637,-0.2480641098102342,-0.026408504701637636,0.3095599986277176,1.0888371155747185,-0.3618795277123087,-1.2455639283657367,-0.11782587038440924,-0.4778031665294185,0.13491897416252877,-1.2234745726017855,-0.45833220142630116,-0.615839256133415,0.3781227390966732,1.4179833366718122,-0.09943703415829816,-0.32371131794603986,-0.30471398246034614,1.787831714138425,0.4459736330867459,-0.615839256133415,-0.26689078457945037,0.4796375690603033,-0.2480641098102342,1.591116683200521,3.239504168358267,-0.6961258399380261,0.3781227390966732,-0.5169291204252513,0.27500609285862937,0.027819650621533694,1.0734929151074688,0.18780780970224395,0.06371823925309218,-0.9857431524258583,0.3267683908998871,-0.7366663610142645,0.2576600004388149,-0.06281812401808029,-0.3810512424874989,-0.19191900263943315,-1.0926332934479581,-0.45833220142630116,-0.32371131794603986,0.22282806736936095,-0.044587330503544284,-0.3618795277123087,0.06371823925309218,-0.9225083508928148,-0.0082812963420422,-0.17331430397827757,-0.21057861160200061,0.27500609285862937,0.2576600004388149,-0.556303522731768,-0.136268113638341,0.4459736330867459,-0.41957202948870276,-0.22929351713387358,1.548235327001688,-0.4973353200537405,-0.22929351713387358,0.00979464113285314,0.4796375690603033,-0.8599277461978309,0.7911712365778563,2.9143381717752534,0.11719253012638,-0.4973353200537405,-0.45833220142630116,-0.19191900263943315,2.4617182325925935,0.6290320310309162,0.49640508473295136,-0.09943703415829816,0.027819650621533694,0.13491897416252877,-0.7366663610142645,0.7267883475768012,0.5796084169446801,-0.43892197167724356,0.8549403888279615,-0.30471398246034614,2.5992012852779514,0.152596792346211,0.8549403888279615,-1.9753880011110494,-0.556303522731768,-0.6961258399380261,1.66200633565837,0.6943623315630637,-0.4002819322572054,-0.26689078457945037,0.3781227390966732,2.1524437074979494,0.3095599986277176,0.06371823925309218,1.0888371155747185,1.8016746579283256,0.6943623315630637,-0.5760850691049697,-0.8185629381819824,0.49640508473295136,3.239504168358267,-0.9857431524258583,2.4364418134826944,1.2553833203983125,-0.2480641098102342,4.883716386323005,-0.4778031665294185,0.8549403888279615,1.3592986669267102,-0.0082812963420422,1.4179833366718122,-0.2480641098102342,-0.2480641098102342,0.6454249718956354,-0.5365850315157712,-0.4973353200537405,0.20534163014615786,0.18780780970224395,-0.11782587038440924,-0.4002819322572054,-1.1795408022055565,-1.0069696246438355,0.00979464113285314,1.2254023183728662,1.5050886200820657,3.2281286571511263,0.8390548805690391,0.9962472414082676,0.00979464113285314
2,773
Mitochondrial biogenesis
11
31
2.382253
0.017207
P00846,P56385,Q9Y512,Q16891,Q13505,Q6UXV4,Q5XKP0,O75431,P00367,O75964,O00411
Processes and pathways
Reactome Pathways
msigdb_reactome
1,322,197,421,11,303,172,88,408,122,309
309,88,728,122,408,1,1992,431,1234,730,1549,712,2589,2671,796,2574,933,1128,322,1428,759,11,1560,421,172,303,1776,2624,629,532,197
1.0734929151074688,2.1918330750978643,0.36104948014525085,1.8978244995764642,0.8865991164842625,5.209596006329733,-0.4973353200537405,0.8231316615590936,-0.06281812401808029,0.36104948014525085,-0.2480641098102342,0.3781227390966732,-1.0711024232199626,-1.289991216052848,0.29230599528747064,-1.049648621318993,0.152596792346211,0.00979464113285314,1.0581139876819772,-0.17331430397827757,0.3267683908998871,3.6489374258930978,-0.2480641098102342,0.8549403888279615,1.591116683200521,1.0888371155747185,-0.3618795277123087,-1.1359288896386077,0.49640508473295136,0.6290320310309162,1.5050886200820657
2,773
Cellular response to chemical stress
15
71
2.382011
0.017218
P09601,P13073,Q8TCT9,P00403,P28072,P33527,P49721,P49720,P30519,P28070,Q96HE7,P60900,P25787,P25789,P20618
Processes and pathways
Reactome Pathways
msigdb_reactome
285,130,98,227,263,166,70,296,43,142,177,302,81,301,279
491,2355,929,825,2049,827,908,1148,615,2474,227,1992,843,285,951,1388,130,756,1096,1832,279,501,1684,81,1290,301,931,142,263,321,1960,2736,2661,2378,43,2211,166,2361,1481,1052,1518,609,296,70,1266,1297,1694,302,783,852,870,1696,1337,1426,1697,801,2067,1402,1060,1061,1911,1776,98,1706,177,428,600,1881,1849,1048,1711
0.6780898876897556,-0.7570377557857778,0.152596792346211,0.2576600004388149,-0.5365850315157712,0.2576600004388149,0.17022630011855963,-0.0082812963420422,0.49640508473295136,-0.9015762556906748,1.344549265567791,-0.4973353200537405,0.2402674242042158,1.1194220763424934,0.13491897416252877,-0.15476413359326763,1.829279487006994,0.3267683908998871,0.027819650621533694,-0.4002819322572054,1.134663203113307,0.66177751226445,-0.32371131794603986,2.3087285106625295,-0.09943703415829816,1.0888371155747185,0.152596792346211,1.7321867892631835,1.195289557247196,1.0581139876819772,-0.4778031665294185,-1.826734486093669,-1.267735897113304,-0.7774772867789987,2.8667161497801694,-0.6358128758210178,1.6195587374943998,-0.7570377557857778,-0.21057861160200061,0.06371823925309218,-0.22929351713387358,0.5131299780208094,1.1041467746508826,2.4364418134826944,-0.08110123928284446,-0.09943703415829816,-0.32371131794603986,1.0888371155747185,0.3095599986277176,0.2402674242042158,0.22282806736936095,-0.32371131794603986,-0.11782587038440924,-0.17331430397827757,-0.32371131794603986,0.29230599528747064,-0.5365850315157712,-0.15476413359326763,0.06371823925309218,0.06371823925309218,-0.43892197167724356,-0.3618795277123087,2.1128376187786273,-0.32371131794603986,1.5768521422780388,0.8390548805690391,0.5298125052139352,-0.41957202948870276,-0.4002819322572054,0.08159248636584522,-0.32371131794603986
2,773
Abnormal epiphyseal ossification
10
14
2.365278
0.018017
Q9UG56,O00116,P10644,Q15125,Q96HY6,Q14739,P38435,O75381,P50542,P08236
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
196,481,578,74,250,76,327,396,313,587
481,2642,396,587,578,327,635,313,76,1431,74,901,250,196
0.6943623315630637,-1.2014671028546344,0.9023727529414285,0.5298125052139352,0.546452920177871,1.0427001461522951,0.4796375690603033,1.0734929151074688,2.372865186563945,-0.17331430397827757,2.4237707360140495,0.18780780970224395,1.2404092037293961,1.5050886200820657
2,773
oxidase
7
15
2.362001
0.018177
P13073,Q6ZRP7,O75845,P14406,Q8NB78,P20674,Q15800
Functions
Panther Protein class
panther_protein_class
130,526,143,18,274,501,187
908,1990,143,615,1388,130,18,756,501,914,1394,187,526,274,1380
0.17022630011855963,-0.4973353200537405,1.7182066280572748,0.49640508473295136,-0.15476413359326763,1.829279487006994,3.4081310510533864,0.3267683908998871,0.66177751226445,0.17022630011855963,-0.15476413359326763,1.5338827670309567,0.6290320310309162,1.1498703359019637,-0.136268113638341
2,773
Polydactyly
10
36
2.359926
0.018279
P61978,O43924,Q15125,Q14739,O75845,P21964,Q9UHX1,O95202,Q15067,Q10713
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
201,10,74,76,143,206,239,341,186,222
10,1637,143,341,586,1547,2649,206,1150,2183,2504,1766,201,355,732,222,1103,2239,76,1941,186,74,1159,1038,2270,2320,1737,1313,1628,2371,920,2200,1673,1570,239,1320
3.7983699214209543,-0.30471398246034614,1.7182066280572748,1.0117669641918954,0.5298125052139352,-0.2480641098102342,-1.2234745726017855,1.4471401018248031,-0.0082812963420422,-0.615839256133415,-0.9435131294526775,-0.3618795277123087,1.4761747942022012,0.9651005639747406,0.36104948014525085,1.374016616607502,0.027819650621533694,-0.6558515089254989,2.372865186563945,-0.45833220142630116,1.5338827670309567,2.4237707360140495,-0.0082812963420422,0.08159248636584522,-0.6759556600324522,-0.7163625657538544,-0.3427663604137081,-0.09943703415829816,-0.2857739408302759,-0.7570377557857778,0.17022630011855963,-0.615839256133415,-0.30471398246034614,-0.2480641098102342,1.2852339236651187,-0.09943703415829816
2,773
Oxidase
6
21
2.355119
0.018517
O43169,O75845,O15254,P14406,O15260,Q15800
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
8,143,111,18,180,187
111,180,8,908,143,615,1388,2749,2451,18,756,501,2261,914,2263,186,187,526,787,1537,1380
1.9926902049699322,1.548235327001688,3.903383190265321,0.17022630011855963,1.7182066280572748,0.49640508473295136,-0.15476413359326763,-2.3115963538256112,-0.8807162496476115,3.4081310510533864,0.3267683908998871,0.66177751226445,-0.6759556600324522,0.17022630011855963,-0.6759556600324522,1.5338827670309567,1.5338827670309567,0.6290320310309162,0.3095599986277176,-0.22929351713387358,-0.136268113638341
2,773
Metalloexopeptidase activity
6
19
2.3551
0.018518
Q969V3,Q9NZ08,Q9NQW7,Q7Z2K6,P55786,O75844
Functions
GO Molecular function
msigdb_gomf
39,108,80,114,23,56
56,670,892,454,2502,2570,914,23,623,114,39,1879,2348,2513,225,80,1709,108,352
2.6608541324132817,0.42907668779468716,0.18780780970224395,0.7751335984561154,-0.9435131294526775,-1.049648621318993,0.17022630011855963,3.341126344179749,0.49640508473295136,1.979215045184117,2.949856816516709,-0.41957202948870276,-0.7366663610142645,-0.9435131294526775,1.3592986669267102,2.3216012131230053,-0.32371131794603986,2.046338095095178,0.980691839776418
2,773
F-type and V-type ATPases
9
16
2.349573
0.018795
P00846,P56385,Q9Y5K8,P36542,Q93050,P06576,P61421,P24539,Q9Y487
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
1,322,631,712,53,431,690,730,163
728,1,431,997,2427,730,1549,712,1360,1128,322,690,53,1277,163,631
0.36104948014525085,5.209596006329733,0.8231316615590936,0.09941714153263233,-0.8392101662750319,0.36104948014525085,-0.2480641098102342,0.3781227390966732,-0.136268113638341,0.00979464113285314,1.0581139876819772,0.41213607006932595,2.6731231556376405,-0.08110123928284446,1.66200633565837,0.49640508473295136
2,773
Abc transporter disorders
14
42
2.349496
0.018799
Q9UBV2,P28074,P28072,P49721,P49720,O00231,Q9GZP9,P28070,Q9BUN8,P60900,Q99436,P25787,P25789,P20618
Processes and pathways
Reactome Pathways
msigdb_reactome
516,321,263,70,296,491,601,142,47,302,600,81,301,279
491,2355,825,2049,827,1148,1387,1096,279,1684,81,1290,301,931,142,263,321,2361,1518,609,296,70,1266,1694,1334,302,783,852,870,1696,1697,801,1060,1061,1706,600,1881,47,601,516,1048,1711
0.6780898876897556,-0.7570377557857778,0.2576600004388149,-0.5365850315157712,0.2576600004388149,-0.0082812963420422,-0.15476413359326763,0.027819650621533694,1.134663203113307,-0.32371131794603986,2.3087285106625295,-0.09943703415829816,1.0888371155747185,0.152596792346211,1.7321867892631835,1.195289557247196,1.0581139876819772,-0.7570377557857778,-0.22929351713387358,0.5131299780208094,1.1041467746508826,2.4364418134826944,-0.08110123928284446,-0.32371131794603986,-0.11782587038440924,1.0888371155747185,0.3095599986277176,0.2402674242042158,0.22282806736936095,-0.32371131794603986,-0.32371131794603986,0.29230599528747064,0.06371823925309218,0.06371823925309218,-0.32371131794603986,0.5298125052139352,-0.41957202948870276,2.7947084048494197,0.5298125052139352,0.6454249718956354,0.08159248636584522,-0.32371131794603986
2,773
Defective cftr causes cystic fibrosis
14
42
2.349496
0.018799
Q9UBV2,P28074,P28072,P49721,P49720,O00231,Q9GZP9,P28070,Q9BUN8,P60900,Q99436,P25787,P25789,P20618
Processes and pathways
Reactome Pathways
msigdb_reactome
516,321,263,70,296,491,601,142,47,302,600,81,301,279
491,2355,825,2049,827,1148,1387,1096,279,1684,81,1290,301,931,142,263,321,2361,1518,609,296,70,1266,1694,1334,302,783,852,870,1696,1697,801,1060,1061,1706,600,1881,47,601,516,1048,1711
0.6780898876897556,-0.7570377557857778,0.2576600004388149,-0.5365850315157712,0.2576600004388149,-0.0082812963420422,-0.15476413359326763,0.027819650621533694,1.134663203113307,-0.32371131794603986,2.3087285106625295,-0.09943703415829816,1.0888371155747185,0.152596792346211,1.7321867892631835,1.195289557247196,1.0581139876819772,-0.7570377557857778,-0.22929351713387358,0.5131299780208094,1.1041467746508826,2.4364418134826944,-0.08110123928284446,-0.32371131794603986,-0.11782587038440924,1.0888371155747185,0.3095599986277176,0.2402674242042158,0.22282806736936095,-0.32371131794603986,-0.32371131794603986,0.29230599528747064,0.06371823925309218,0.06371823925309218,-0.32371131794603986,0.5298125052139352,-0.41957202948870276,2.7947084048494197,0.5298125052139352,0.6454249718956354,0.08159248636584522,-0.32371131794603986
2,773
S phase
28
89
2.332826
0.019657
Q9NR33,P28072,P11802,P28070,P20618,P30260,Q14566,P49720,Q9UBD5,Q9UJX3,P41440,P60900,P25789,Q9BRT9,P25205,P28074,P49721,Q9Y248,Q9Y619,Q99436,Q96DE5,P25787,P31751,Q16763,P33991,O00231,P49643,Q9UJX2
Processes and pathways
Reactome Pathways
msigdb_reactome
131,263,510,142,279,415,549,296,174,566,171,302,301,443,192,321,70,463,203,600,207,81,210,594,589,491,493,382
491,2355,825,2049,827,2124,1637,1148,1208,510,2092,1869,1096,844,279,1391,192,1684,81,1290,301,1580,931,142,263,321,1514,415,711,210,589,1643,1644,1180,2534,2212,2334,2361,2652,1833,2024,171,1518,609,1101,493,296,70,981,1266,1694,302,783,852,870,1696,1337,1697,760,801,2067,963,549,2068,1007,1060,1061,594,1595,1665,1038,1706,207,600,1881,443,1375,131,2295,174,382,566,972,1048,1711,1502,463,1278,203
0.6780898876897556,-0.7570377557857778,0.2576600004388149,-0.5365850315157712,0.2576600004388149,-0.5760850691049697,-0.30471398246034614,-0.0082812963420422,-0.044587330503544284,0.6454249718956354,-0.556303522731768,-0.41957202948870276,0.027819650621533694,0.2402674242042158,1.134663203113307,-0.15476413359326763,1.5195005799200332,-0.32371131794603986,2.3087285106625295,-0.09943703415829816,1.0888371155747185,-0.26689078457945037,0.152596792346211,1.7321867892631835,1.195289557247196,1.0581139876819772,-0.22929351713387358,0.8707883976495787,0.3781227390966732,1.4179833366718122,0.5298125052139352,-0.30471398246034614,-0.30471398246034614,-0.026408504701637636,-0.9857431524258583,-0.6358128758210178,-0.7366663610142645,-0.7570377557857778,-1.2234745726017855,-0.4002819322572054,-0.5169291204252513,1.591116683200521,-0.22929351713387358,0.5131299780208094,0.027819650621533694,0.6780898876897556,1.1041467746508826,2.4364418134826944,0.11719253012638,-0.08110123928284446,-0.32371131794603986,1.0888371155747185,0.3095599986277176,0.2402674242042158,0.22282806736936095,-0.32371131794603986,-0.11782587038440924,-0.32371131794603986,0.3267683908998871,0.29230599528747064,-0.5365850315157712,0.13491897416252877,0.5961239946346427,-0.5365850315157712,0.09941714153263233,0.06371823925309218,0.06371823925309218,0.5298125052139352,-0.26689078457945037,-0.30471398246034614,0.08159248636584522,-0.32371131794603986,1.4471401018248031,0.5298125052139352,-0.41957202948870276,0.8071705185983409,-0.136268113638341,1.829279487006994,-0.6961258399380261,1.591116683200521,0.9338096000880001,0.5796084169446801,0.13491897416252877,0.08159248636584522,-0.32371131794603986,-0.21057861160200061,0.7590573852352058,-0.08110123928284446,1.4761747942022012
2,773
Cholesterol metabolism
6
22
2.328326
0.019895
Q15392,P37268,Q15125,Q14739,Q16850,Q15800
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
99,38,74,76,120,187
283,1387,1754,633,1149,1448,590,38,2441,2214,2338,832,1058,2313,76,74,2070,99,901,187,120,2300
1.1194220763424934,-0.15476413359326763,-0.3618795277123087,0.4796375690603033,-0.0082812963420422,-0.19191900263943315,0.5298125052139352,2.949856816516709,-0.8599277461978309,-0.6358128758210178,-0.7366663610142645,0.2576600004388149,0.06371823925309218,-0.7163625657538544,2.372865186563945,2.4237707360140495,-0.5365850315157712,2.099586937710835,0.18780780970224395,1.5338827670309567,1.9250582352755141,-0.6961258399380261
2,773
Monovalent inorganic cation homeostasis
12
22
2.32749
0.019939
P50897,Q8N511,P04899,P51790,P28482,P27361,P05023,Q15904,Q93050,P06576,O75503,Q9Y487
Processes and pathways
GO Biological process
msigdb_gobp
129,35,284,447,354,262,397,525,53,431,499,163
499,284,397,431,262,354,129,1053,447,758,2663,690,1367,525,35,53,857,1575,1277,163,584,2722
0.66177751226445,1.1194220763424934,0.9023727529414285,0.8231316615590936,1.195289557247196,0.9651005639747406,1.8430416218620376,0.06371823925309218,0.7911712365778563,0.3267683908998871,-1.267735897113304,0.41213607006932595,-0.136268113638341,0.6290320310309162,3.0786729040592555,2.6731231556376405,0.2402674242042158,-0.2480641098102342,-0.08110123928284446,1.66200633565837,0.546452920177871,-1.5638395884882637
2,773
Sensory perception of light stimulus
6
15
2.327333
0.019948
Q9H6K4,P50897,Q99797,O43924,Q13432,O76024
Processes and pathways
GO Biological process
msigdb_gobp
224,129,387,10,46,367
10,458,1386,1093,367,2532,129,1057,46,936,2110,702,2074,387,224
3.7983699214209543,0.7590573852352058,-0.15476413359326763,0.027819650621533694,0.9338096000880001,-0.9857431524258583,1.8430416218620376,0.06371823925309218,2.8187883958279008,0.152596792346211,-0.556303522731768,0.3951515110109617,-0.5365850315157712,0.918109512811578,1.3592986669267102
2,773
Nervous system process
27
86
2.326007
0.020018
P50897,Q99797,Q9Y6M9,P07196,P27361,O43924,Q8NBU5,Q92542,Q8N0X7,Q13432,Q9Y5J9,P50542,Q14168,O75844,O75915,Q9UQB8,O60313,O00264,Q9Y5L4,Q9H6K4,P28482,Q96P11,Q14108,O14773,Q99808,Q9Y639,O76024
Processes and pathways
GO Biological process
msigdb_gobp
129,387,134,383,262,10,423,424,426,46,430,313,183,56,446,68,458,87,345,224,354,364,104,492,378,255,367
1924,87,1145,492,10,458,2424,1860,2597,669,1386,1093,1753,56,446,367,2407,633,1992,2532,1177,2053,383,2751,588,2548,930,710,262,1685,354,711,1612,1719,2652,879,1032,1934,2310,1798,313,129,1585,2311,1397,1299,1838,1057,934,503,1155,660,46,1872,104,183,1059,2444,2192,2002,936,1492,767,1186,426,423,2110,424,702,2040,364,1068,2074,387,378,1849,2200,224,1316,2567,2449,68,430,345,255,134
-0.45833220142630116,2.2179736349774104,-0.0082812963420422,0.6780898876897556,3.7983699214209543,0.7590573852352058,-0.8392101662750319,-0.41957202948870276,-1.0926332934479581,0.42907668779468716,-0.15476413359326763,0.027819650621533694,-0.3618795277123087,2.6608541324132817,0.7911712365778563,0.9338096000880001,-0.8185629381819824,0.4796375690603033,-0.4973353200537405,-0.9857431524258583,-0.026408504701637636,-0.5365850315157712,0.918109512811578,-2.3651721003221735,0.5298125052139352,-1.0069696246438355,0.152596792346211,0.3781227390966732,1.195289557247196,-0.32371131794603986,0.9651005639747406,0.3781227390966732,-0.2857739408302759,-0.3427663604137081,-1.2234745726017855,0.20534163014615786,0.08159248636584522,-0.45833220142630116,-0.7163625657538544,-0.3810512424874989,1.0734929151074688,1.8430416218620376,-0.26689078457945037,-0.7163625657538544,-0.15476413359326763,-0.09943703415829816,-0.4002819322572054,0.06371823925309218,0.152596792346211,0.66177751226445,-0.0082812963420422,0.4459736330867459,2.8187883958279008,-0.41957202948870276,2.046338095095178,1.548235327001688,0.06371823925309218,-0.8599277461978309,-0.615839256133415,-0.4973353200537405,0.152596792346211,-0.21057861160200061,0.3267683908998871,-0.026408504701637636,0.8390548805690391,0.8549403888279615,-0.556303522731768,0.8549403888279615,0.3951515110109617,-0.5169291204252513,0.9494732169881561,0.06371823925309218,-0.5365850315157712,0.918109512811578,0.9338096000880001,-0.4002819322572054,-0.615839256133415,1.3592986669267102,-0.09943703415829816,-1.028271236117502,-0.8599277461978309,2.486907600894611,0.8390548805690391,0.9962472414082676,1.2254023183728662,1.8016746579283256
2,773
Respiratory chain
11
30
2.318554
0.020419
O43676,Q9P0J0,P00403,O96000,Q9Y6M9,Q6DKK2,P22695,Q96CU9,Q9UDW1,Q86Y39,O14949
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
34,226,227,293,134,167,398,465,52,86,55
929,55,34,1636,1385,1176,672,2278,1680,293,227,557,779,2260,398,2306,1099,757,2677,636,2602,884,1460,167,86,465,490,226,52,134
0.152596792346211,2.6608541324132817,3.0786729040592555,-0.30471398246034614,-0.15476413359326763,-0.026408504701637636,0.42907668779468716,-0.6961258399380261,-0.32371131794603986,1.1041467746508826,1.344549265567791,0.5796084169446801,0.3095599986277176,-0.6759556600324522,0.9023727529414285,-0.7163625657538544,0.027819650621533694,0.3267683908998871,-1.3347549057430848,0.4796375690603033,-1.0926332934479581,0.20534163014615786,-0.19191900263943315,1.6195587374943998,2.2310085155951622,0.7429423759366403,0.6943623315630637,1.3592986669267102,2.721996774098279,1.8016746579283256
2,773
Nucleophile aminohydrolases, N-terminal [IPR029055]
8
18
2.318188
0.020439
P28072,P49721,P49720,P28070,P60900,P25787,P25789,P20618
Sequence
InterPro Superfamily
interpro_homologous_superfamily
263,70,296,142,302,81,301,279
2049,1512,279,1684,81,1290,301,931,142,263,321,296,70,302,813,2637,2718,600
-0.5365850315157712,-0.22929351713387358,1.134663203113307,-0.32371131794603986,2.3087285106625295,-0.09943703415829816,1.0888371155747185,0.152596792346211,1.7321867892631835,1.195289557247196,1.0581139876819772,1.1041467746508826,2.4364418134826944,1.0888371155747185,0.27500609285862937,-1.1795408022055565,-1.5405225510761564,0.5298125052139352
2,773
Dicarboxylic acid transport
8
14
2.316341
0.02054
O75915,Q02978,Q9H2D1,Q9UJS0,P41440,Q9UBX3,O60831,Q9BQT8
Processes and pathways
GO Biological process
msigdb_gobp
446,228,71,403,171,79,208,20
208,1753,446,1177,171,2663,228,2444,538,20,71,946,79,403
1.4325770544795577,-0.3618795277123087,0.7911712365778563,-0.026408504701637636,1.591116683200521,-1.267735897113304,1.3297682525174959,-0.8599277461978309,0.6125984519295641,3.385861236908578,2.4364418134826944,0.152596792346211,2.3344511368079344,0.9023727529414285
2,773
Limb undergrowth
9
39
3.18787
0.001433
Q15392,O94761,Q15125,P48735,Q96HY6,O75874,Q03164,O75718,P98175
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
1,92,35,36,109,198,84,239,154
1325,1811,1956,1700,2197,254,1331,239,198,92,1540,727,2268,1709,2375,881,1148,1341,2277,1343,36,404,950,1670,154,84,545,1216,1677,35,1,696,1294,109,2187,1691,1696,920,2366
-0.011883605779959972,-0.27112873617318034,-0.3679300959829081,-0.20646664342063079,-0.528740588862393,0.9401810366079315,-0.011883605779959972,0.9733270109001069,1.1061073370230785,1.5732267389676968,-0.10928561936443627,0.3470721765493684,-0.5928759563454861,-0.20646664342063079,-0.6888709751485222,0.24889951105491837,0.08573457717198472,-0.011883605779959972,-0.5928759563454861,-0.011883605779959972,2.48379688614699,0.6757387821081435,0.21622048902616958,-0.17409783001571622,1.2391965779540524,1.640250446718315,0.5111363093248045,0.053171452532358235,-0.17409783001571622,2.5177504135849333,8.654602892981343,0.3798410926299849,0.02063200139086309,1.4728255311254135,-0.496631996390989,-0.17409783001571622,-0.17409783001571622,0.24889951105491837,-0.6569006902908113
2,771
Striated muscle cell differentiation
8
40
2.888817
0.003867
Q9H7B4,P11310,O75844,P27797,P31749,P78310,P35609,Q9NYL9
Processes and pathways
GO Biological process
msigdb_gobp
0,2,91,255,138,181,122,298
1467,1916,91,2055,1468,501,1087,1471,727,2,2372,255,138,1265,122,2648,2277,1201,1097,2468,512,181,1770,1774,895,1364,958,1217,1431,2703,582,2215,1018,760,914,0,298,1856,347,1953
-0.07684259325485089,-0.3356888137048316,1.5732267389676968,-0.432334116613742,-0.07684259325485089,0.5440142893653486,0.11832120737882174,-0.07684259325485089,0.3470721765493684,8.295210829194325,-0.6888709751485222,0.9401810366079315,1.3058548758449697,0.02063200139086309,1.3725878439280066,-1.290933792931523,-0.5928759563454861,0.053171452532358235,0.11832120737882174,-0.8164657859679018,0.5440142893653486,1.1726137814023248,-0.2388103431729151,-0.2388103431729151,0.24889951105491837,-0.011883605779959972,0.21622048902616958,0.053171452532358235,-0.04437519590684744,-1.7286138447009465,0.47827985913265875,-0.528740588862393,0.1835643251364057,0.3470721765493684,0.24889951105491837,13.178662435389704,0.8739488266751041,-0.27112873617318034,0.7747516486835785,-0.3356888137048316
2,771
Endoplasmic reticulum golgi intermediate compartment
18
41
2.599349
0.00934
Q969H8,P50454,Q12907,P49755,P53990,P30533,P27797,Q9Y282,P80303,Q9Y678,Q9BS26,Q9NYU2,O15260,Q8N511,P07237,P24390,Q14789,Q15084
Localization
GO Cellular component
msigdb_gocc
293,404,169,319,258,317,255,12,13,186,281,149,19,20,422,177,156,325
2336,1814,19,1589,1251,422,563,177,255,317,942,319,404,2554,2208,1204,258,1667,13,1102,2665,169,574,156,325,2735,792,1779,1783,20,460,293,281,149,2252,1391,2333,12,2411,186,1029
-0.6569006902908113,-0.27112873617318034,3.371487381021164,-0.14170409298657155,0.02063200139086309,0.6427760411067371,0.47827985913265875,1.1726137814023248,0.9401810366079315,0.8077970614447516,0.21622048902616958,0.8077970614447516,0.6757387821081435,-0.9753076208950913,-0.528740588862393,0.053171452532358235,0.9401810366079315,-0.17409783001571622,3.9225430291773304,0.11832120737882174,-1.3851178706109986,1.20589568930337,0.47827985913265875,1.2391965779540524,0.8077970614447516,-2.407742706177414,0.31432550755588423,-0.2388103431729151,-0.2388103431729151,3.2342759895389332,0.6098342901811546,0.8739488266751041,0.9070549359123588,1.2725163416320027,-0.560821985003306,-0.011883605779959972,-0.6249022703490457,3.9570982582733887,-0.7208128794806824,1.1726137814023248,0.1835643251364057
2,771
Endoplasmic reticulum lumen
30
53
2.474385
0.013347
Q8NBS9,Q32P28,P30040,P27797,Q15293,Q9BS26,Q9NZ08,Q9NYU2,O43852,Q14257,P55145,Q969H8,P50454,P07237,P27824,P30101,Q9NWM8,Q86UP2,Q15084,P30533,Q07065,Q7Z4H8,P13667,Q8IXB1,O95881,Q13217,Q96AY3,P14314,O75718,Q9Y4L1
Localization
GO Cellular component
msigdb_gocc
517,130,256,255,141,281,17,149,25,31,153,293,404,422,425,427,59,326,325,317,321,457,218,367,216,108,116,358,239,530
2567,2683,980,25,864,239,1085,216,422,2396,218,607,358,539,2375,2417,255,425,2534,256,427,317,404,1204,153,1102,321,108,31,790,693,325,141,130,1164,514,457,326,367,1562,517,293,116,2562,281,1575,2185,59,149,17,1317,530,2547
-1.0069911494769188,-1.5103540181684711,0.1835643251364057,2.858132643714114,0.24889951105491837,0.9733270109001069,0.11832120737882174,1.039678116055493,0.6427760411067371,-0.7208128794806824,1.039678116055493,0.4454450783260045,0.741726713903751,0.5111363093248045,-0.6888709751485222,-0.7527261533018542,0.9401810366079315,0.6427760411067371,-0.943596209546844,0.9401810366079315,0.6427760411067371,0.8077970614447516,0.6757387821081435,0.053171452532358235,1.2391965779540524,0.11832120737882174,0.8077970614447516,1.4728255311254135,2.619704350382639,0.31432550755588423,0.3798410926299849,0.8077970614447516,1.3058548758449697,1.3392120773091511,0.08573457717198472,0.5440142893653486,0.6098342901811546,0.8077970614447516,0.741726713903751,-0.10928561936443627,0.5440142893653486,0.8739488266751041,1.405982074771594,-0.9753076208950913,0.9070549359123588,-0.10928561936443627,-0.496631996390989,1.9090459589787758,1.2725163416320027,3.5777242886426346,0.02063200139086309,0.5440142893653486,-0.943596209546844
2,771
Congenital contracture
6
33
2.430701
0.01507
Q15392,P11310,O75844,Q53EZ4,Q96AY3,Q9NXE4
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
1,2,91,279,116,268
1081,1700,91,501,2266,446,2,1143,2270,1048,998,2113,2524,1774,1104,741,1431,1,279,579,413,1890,2176,311,116,1897,1119,849,2577,268,1699,1953,2366
0.11832120737882174,-0.20646664342063079,1.5732267389676968,0.5440142893653486,-0.5928759563454861,0.6098342901811546,8.295210829194325,0.08573457717198472,-0.5928759563454861,0.15093117770625794,0.1835643251364057,-0.4644964320933728,-0.9118566224269768,-0.2388103431729151,0.11832120737882174,0.3470721765493684,-0.04437519590684744,8.654602892981343,0.9070549359123588,0.47827985913265875,0.6757387821081435,-0.3034216261747569,-0.496631996390989,0.8408628282366563,1.405982074771594,-0.3034216261747569,0.11832120737882174,0.281601235173691,-1.0069911494769188,0.9401810366079315,-0.17409783001571622,-0.3356888137048316,-0.6569006902908113
2,771
Electron transport chain oxphos system in mitochondria
23
47
2.407602
0.016058
P21912,P22695,Q16718,O75947,P00846,O95168,P56385,Q16795,P36542,O75306,O95182,P14927,Q9UII2,P24539,P09669,O43676,P15954,O14949,O75489,O00483,P47985,P06576,P20674
Processes and pathways
WikiPathways
msigdb_wp
380,505,157,396,30,537,287,308,304,187,188,315,74,567,448,83,207,331,475,349,110,356,359
349,331,83,2100,187,475,1196,396,1646,537,188,1537,1650,1651,30,867,356,448,773,640,1598,606,937,315,207,875,359,380,505,567,1144,1600,1090,2312,304,110,1549,2016,2279,2587,287,1967,157,308,918,74,1400
0.741726713903751,0.7747516486835785,1.640250446718315,-0.4644964320933728,1.1393509612256292,0.5769136615924052,0.053171452532358235,0.6757387821081435,-0.17409783001571622,0.5111363093248045,1.1393509612256292,-0.10928561936443627,-0.17409783001571622,-0.17409783001571622,2.619704350382639,0.24889951105491837,0.741726713903751,0.6098342901811546,0.31432550755588423,0.41263210835635755,-0.14170409298657155,0.4454450783260045,0.21622048902616958,0.8077970614447516,1.0728830183428721,0.24889951105491837,0.741726713903751,0.708722382653078,0.5440142893653486,0.47827985913265875,0.08573457717198472,-0.14170409298657155,0.11832120737882174,-0.6249022703490457,0.8408628282366563,1.4393946700563578,-0.10928561936443627,-0.40014526683647345,-0.5928759563454861,-1.038647082516082,0.8739488266751041,-0.3679300959829081,1.2391965779540524,0.8408628282366563,0.24889951105491837,1.7409185060160315,-0.011883605779959972
2,771
Respirasome
18
40
2.361786
0.018187
O75306,O95182,P21912,P14927,P22695,O75489,O00483,P47985,Q9NX14,P09669,Q16795,O43676,P15954,Q16718,Q6DKK2,Q13423,O14949,P20674
Localization
GO Cellular component
msigdb_gocc
187,188,380,315,505,475,349,110,345,448,308,83,207,157,386,26,331,359
349,331,83,2100,187,475,537,188,1537,1650,1651,2002,448,773,606,937,315,207,875,359,380,505,1600,1090,2312,110,2016,2279,1967,26,157,308,386,2323,2356,345,1906,918,810,1400
0.741726713903751,0.7747516486835785,1.640250446718315,-0.4644964320933728,1.1393509612256292,0.5769136615924052,0.5111363093248045,1.1393509612256292,-0.10928561936443627,-0.17409783001571622,-0.17409783001571622,-0.40014526683647345,0.6098342901811546,0.31432550755588423,0.4454450783260045,0.21622048902616958,0.8077970614447516,1.0728830183428721,0.24889951105491837,0.741726713903751,0.708722382653078,0.5440142893653486,-0.14170409298657155,0.11832120737882174,-0.6249022703490457,1.4393946700563578,-0.40014526683647345,-0.5928759563454861,-0.3679300959829081,2.789934629703246,1.2391965779540524,0.8408628282366563,0.708722382653078,-0.6249022703490457,-0.6569006902908113,0.7747516486835785,-0.3034216261747569,0.24889951105491837,0.31432550755588423,-0.011883605779959972
2,771
Response to ketone
9
35
2.311953
0.02078
Q9H7B4,P07196,O75116,P31749,O95831,Q96ST3,Q969T9,Q13185,Q16822
Processes and pathways
GO Biological process
msigdb_gobp
0,151,137,138,46,52,54,208,53
474,137,46,2266,2438,2520,2439,151,1705,1755,1597,1866,2711,678,1478,1144,776,255,138,646,782,2742,2680,1934,2071,208,385,53,1295,54,1446,2689,52,2514,0
0.5769136615924052,1.3058548758449697,2.1451358481617295,-0.5928759563454861,-0.7846105419531825,-0.9118566224269768,-0.7846105419531825,1.2391965779540524,-0.20646664342063079,-0.2388103431729151,-0.14170409298657155,-0.3034216261747569,-1.8838416217729261,0.3798410926299849,-0.07684259325485089,0.08573457717198472,0.31432550755588423,0.9401810366079315,1.3058548758449697,0.41263210835635755,0.31432550755588423,-2.530199752036723,-1.4790810209051384,-0.3356888137048316,-0.432334116613742,1.0728830183428721,0.708722382653078,1.976416489398524,0.02063200139086309,1.976416489398524,-0.04437519590684744,-1.5728292216627975,2.0101270351272507,-0.8800885605751826,13.178662435389704
2,771
Mitochondrial transmembrane transport
16
46
2.280478
0.022579
P00846,Q9Y619,P56385,Q99595,Q8NE86,O60830,O14925,O95831,Q9UJZ1,O43772,O95202,P06576,P36542,P23786,Q6P4A7,O75947
Processes and pathways
GO Biological process
msigdb_gobp
30,203,287,201,340,102,41,46,418,50,420,356,304,302,131,396
41,813,50,102,2394,500,726,396,1646,1468,420,46,421,30,867,356,1141,640,1598,2234,302,567,1144,304,1549,2113,2587,287,1877,1496,1063,131,1785,340,1564,201,2457,712,1183,2038,2220,1453,1239,418,1189,203
2.1789293086297925,0.281601235173691,2.0775982769674175,1.4728255311254135,-0.7208128794806824,0.5440142893653486,0.3470721765493684,0.6757387821081435,-0.17409783001571622,-0.07684259325485089,0.6427760411067371,2.1451358481617295,0.6427760411067371,2.619704350382639,0.24889951105491837,0.741726713903751,0.08573457717198472,0.41263210835635755,-0.14170409298657155,-0.560821985003306,0.8408628282366563,0.47827985913265875,0.08573457717198472,0.8408628282366563,-0.10928561936443627,-0.4644964320933728,-1.038647082516082,0.8739488266751041,-0.3034216261747569,-0.07684259325485089,0.15093117770625794,1.3392120773091511,-0.2388103431729151,0.7747516486835785,-0.10928561936443627,1.1061073370230785,-0.7846105419531825,0.3798410926299849,0.08573457717198472,-0.40014526683647345,-0.528740588862393,-0.04437519590684744,0.053171452532358235,0.6757387821081435,0.08573457717198472,1.1061073370230785
2,771
Response to temperature stimulus
6
43
2.252003
0.024322
Q96EY1,P11310,Q13217,P49748,P04179,Q14011
Processes and pathways
GO Biological process
msigdb_gobp
67,2,108,22,121,123
865,533,1330,932,1863,1651,121,1411,1594,936,1198,1258,1141,2,605,2268,1478,2311,1547,138,2277,22,2507,1606,1923,1275,2071,692,108,123,1620,552,2689,67,2562,1636,2475,1230,2476,1583,1391,2581,374
0.24889951105491837,0.5111363093248045,-0.011883605779959972,0.21622048902616958,-0.3034216261747569,-0.17409783001571622,1.3725878439280066,-0.04437519590684744,-0.14170409298657155,0.21622048902616958,0.053171452532358235,0.02063200139086309,0.08573457717198472,8.295210829194325,0.4454450783260045,-0.5928759563454861,-0.07684259325485089,-0.6249022703490457,-0.10928561936443627,1.3058548758449697,-0.5928759563454861,3.0288878959853394,-0.8800885605751826,-0.14170409298657155,-0.3356888137048316,0.02063200139086309,-0.432334116613742,0.3798410926299849,1.4728255311254135,1.3725878439280066,-0.14170409298657155,0.5111363093248045,-1.5728292216627975,1.8417434008112452,-0.9753076208950913,-0.14170409298657155,-0.8164657859679018,0.053171452532358235,-0.8164657859679018,-0.10928561936443627,-0.011883605779959972,-1.0069911494769188,0.741726713903751
2,771
Coma
6
31
2.249979
0.02445
P11310,P35670,Q9Y619,O43772,P35610,Q13423
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
2,68,203,50,303,26
50,1592,1704,1864,2,1259,610,302,877,819,612,1264,303,68,1266,823,1048,1827,944,1152,2696,949,26,1289,1290,2561,2513,2293,1310,1239,203
2.0775982769674175,-0.14170409298657155,-0.20646664342063079,-0.3034216261747569,8.295210829194325,0.02063200139086309,0.4454450783260045,0.8408628282366563,0.24889951105491837,0.281601235173691,0.4454450783260045,0.02063200139086309,0.8408628282366563,1.8081178236928688,0.02063200139086309,0.281601235173691,0.15093117770625794,-0.27112873617318034,0.21622048902616958,0.08573457717198472,-1.6352114202314667,0.21622048902616958,2.789934629703246,0.02063200139086309,0.02063200139086309,-0.9753076208950913,-0.8800885605751826,-0.5928759563454861,0.02063200139086309,0.053171452532358235,1.1061073370230785
2,771
Mitochondrial respiratory chain complex assembly
14
35
2.224751
0.026098
O75306,O95168,Q9Y2R0,Q7L592,O75489,O95831,Q9NX14,P47985,Q16795,Q00059,O43676,Q16718,Q6DKK2,Q9H061
Processes and pathways
GO Biological process
msigdb_gobp
187,537,375,72,475,46,345,110,308,430,83,157,386,267
83,1534,2100,187,475,1196,537,1537,46,1650,1600,110,2279,1967,430,1679,157,308,1436,386,72,2323,2326,2356,590,267,807,2189,345,1126,1906,810,375,1079,1400
1.640250446718315,-0.10928561936443627,-0.4644964320933728,1.1393509612256292,0.5769136615924052,0.053171452532358235,0.5111363093248045,-0.10928561936443627,2.1451358481617295,-0.17409783001571622,-0.14170409298657155,1.4393946700563578,-0.5928759563454861,-0.3679300959829081,0.6427760411067371,-0.17409783001571622,1.2391965779540524,0.8408628282366563,-0.04437519590684744,0.708722382653078,1.7409185060160315,-0.6249022703490457,-0.6249022703490457,-0.6569006902908113,0.47827985913265875,0.9401810366079315,0.31432550755588423,-0.496631996390989,0.7747516486835785,0.11832120737882174,-0.3034216261747569,0.31432550755588423,0.741726713903751,0.15093117770625794,-0.011883605779959972
2,771
Positive regulation of mapk cascade
8
40
2.163636
0.030492
Q6IAA8,Q9UMX5,P30040,O75116,Q9Y639,Q9Y2Q5,P04899,O75915
Processes and pathways
GO Biological process
msigdb_gobp
171,6,256,137,11,215,56,270
2640,1247,2150,1467,137,270,56,1705,563,2619,990,1261,876,1042,2417,992,256,643,1264,683,2447,1200,1829,1418,2468,1608,740,1488,2637,1433,171,293,969,1382,1120,2358,6,215,470,11
-1.2594889256252415,0.02063200139086309,-0.496631996390989,-0.07684259325485089,1.3058548758449697,0.9070549359123588,1.9427227696891576,-0.20646664342063079,0.47827985913265875,-1.133452097357016,0.1835643251364057,0.02063200139086309,0.24889951105491837,0.15093117770625794,-0.7527261533018542,0.1835643251364057,0.9401810366079315,0.41263210835635755,0.02063200139086309,0.3798410926299849,-0.7846105419531825,0.053171452532358235,-0.27112873617318034,-0.04437519590684744,-0.8164657859679018,-0.14170409298657155,0.3470721765493684,-0.07684259325485089,-1.2280185712198608,-0.04437519590684744,1.20589568930337,0.8739488266751041,0.21622048902616958,-0.011883605779959972,0.11832120737882174,-0.6569006902908113,5.876636122044149,1.0728830183428721,0.6098342901811546,4.1647038052724294
2,771
Negative regulation of mrna metabolic process
24
41
2.137188
0.032583
Q14103,O75150,Q13247,P61978,O00422,P67809,P35637,P07910,P38159,P26599,P98175,Q92804,Q6PJT7,Q13151,P26368,Q9H074,P22626,Q92615,Q16629,Q9Y2W1,Q13242,Q99729,Q12872,Q14011
Processes and pathways
GO Biological process
msigdb_gobp
385,127,384,407,630,512,274,272,275,641,154,43,431,306,681,194,679,752,222,498,363,119,654,123
1242,630,1249,127,1136,1818,272,872,1261,679,681,641,274,275,407,512,154,1770,1159,2716,1933,654,2170,306,363,384,123,385,1163,743,2703,222,963,431,1295,752,43,119,194,1515,498
0.02063200139086309,0.41263210835635755,0.02063200139086309,1.3392120773091511,0.08573457717198472,-0.27112873617318034,0.9070549359123588,0.24889951105491837,0.02063200139086309,0.3798410926299849,0.3798410926299849,0.41263210835635755,0.9070549359123588,0.9070549359123588,0.6757387821081435,0.5440142893653486,1.2391965779540524,-0.2388103431729151,0.08573457717198472,-1.9767205052368426,-0.3356888137048316,0.41263210835635755,-0.496631996390989,0.8408628282366563,0.741726713903751,0.708722382653078,1.3725878439280066,0.708722382653078,0.08573457717198472,0.3470721765493684,-1.7286138447009465,1.039678116055493,0.21622048902616958,0.6427760411067371,0.02063200139086309,0.3470721765493684,2.1789293086297925,1.405982074771594,1.1393509612256292,-0.07684259325485089,0.5769136615924052
2,771
EF-hand domain [IPR002048]
7
38
2.08065
0.037466
O95302,P80303,Q96AY3,O43852,P35609,Q9NWM8,Q14257
Sequence
InterPro Domain
interpro_domain
3,13,116,25,122,59,31
724,25,2723,1330,726,420,3,604,728,2061,358,273,1601,1548,122,2346,1350,13,1102,2760,576,31,1937,141,1166,962,1297,1560,1785,518,116,2457,914,59,2749,1239,419,2547
0.3470721765493684,2.858132643714114,-2.1311037624058486,-0.011883605779959972,0.3470721765493684,0.6427760411067371,6.6895020493856965,0.4454450783260045,0.3470721765493684,-0.432334116613742,0.741726713903751,0.9070549359123588,-0.14170409298657155,-0.10928561936443627,1.3725878439280066,-0.6569006902908113,-0.011883605779959972,3.9225430291773304,0.11832120737882174,-3.56005836221333,0.47827985913265875,2.619704350382639,-0.3356888137048316,1.3058548758449697,0.08573457717198472,0.21622048902616958,0.02063200139086309,-0.10928561936443627,-0.2388103431729151,0.5440142893653486,1.405982074771594,-0.7846105419531825,0.24889951105491837,1.9090459589787758,-2.743802829855839,0.053171452532358235,0.6757387821081435,-0.943596209546844
2,771
mRNA splicing factor
28
58
2.078438
0.037669
Q13595,Q96E39,O43809,Q13247,P35637,P38159,P33240,Q96PU8,Q92804,Q8IWZ8,Q9UBB9,O75934,P08621,Q01844,Q13243,Q9BZJ0,Q16629,Q15233,P19338,P98179,Q13242,Q14011,P62995,P23246,Q15428,Q12872,Q07955,Q96PK6
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
261,133,126,384,274,275,644,39,43,699,60,445,447,573,575,494,222,221,242,93,363,123,104,231,484,654,260,392
1082,2262,2264,126,1136,1407,445,1469,989,447,816,1541,242,231,644,274,275,1768,1969,886,1551,104,689,93,573,1211,260,1103,654,1675,363,575,384,261,123,1623,221,1163,1106,484,903,1219,222,2353,1011,699,965,1847,2643,843,43,133,392,39,713,494,1233,60
0.11832120737882174,-0.5928759563454861,-0.5928759563454861,1.3392120773091511,0.08573457717198472,-0.04437519590684744,0.6098342901811546,-0.07684259325485089,0.1835643251364057,0.6098342901811546,0.281601235173691,-0.10928561936443627,0.9733270109001069,1.0064927423781989,0.41263210835635755,0.9070549359123588,0.9070549359123588,-0.2388103431729151,-0.3679300959829081,0.24889951105491837,-0.10928561936443627,1.4728255311254135,0.3798410926299849,1.5732267389676968,0.47827985913265875,0.053171452532358235,0.9401810366079315,0.11832120737882174,0.41263210835635755,-0.17409783001571622,0.741726713903751,0.47827985913265875,0.708722382653078,0.9401810366079315,1.3725878439280066,-0.14170409298657155,1.039678116055493,0.08573457717198472,0.11832120737882174,0.5769136615924052,0.24889951105491837,0.053171452532358235,1.039678116055493,-0.6569006902908113,0.1835643251364057,0.3798410926299849,0.21622048902616958,-0.27112873617318034,-1.2594889256252415,0.281601235173691,2.1789293086297925,1.3392120773091511,0.708722382653078,2.212739114662294,0.3798410926299849,0.5769136615924052,0.053171452532358235,1.9090459589787758
2,771
Cellular response to oxygen levels
7
34
2.075449
0.037945
O75306,Q99808,O75116,P31749,O95831,Q8N511,P55786
Processes and pathways
GO Biological process
msigdb_gobp
187,8,137,138,46,20,29
137,187,2101,46,1960,501,866,2309,422,1198,1480,138,1267,2277,1417,2419,29,951,2071,1430,792,1165,2685,20,844,2689,2562,1120,8,250,374,1643,530,2257
1.3058548758449697,1.1393509612256292,-0.4644964320933728,2.1451358481617295,-0.3679300959829081,0.5440142893653486,0.24889951105491837,-0.6249022703490457,0.6427760411067371,0.053171452532358235,-0.07684259325485089,1.3058548758449697,0.02063200139086309,-0.5928759563454861,-0.04437519590684744,-0.7527261533018542,2.6877507437971997,0.21622048902616958,-0.432334116613742,-0.04437519590684744,0.31432550755588423,0.08573457717198472,-1.5103540181684711,3.2342759895389332,0.281601235173691,-1.5728292216627975,-0.9753076208950913,0.11832120737882174,5.630370435962049,0.9733270109001069,0.741726713903751,-0.14170409298657155,0.5440142893653486,-0.560821985003306
2,771
Phagocytosis
7
32
2.055041
0.039875
P51809,Q12907,Q8WTV0,P20339,P04083,Q08722,Q96JJ3
Processes and pathways
GO Biological process
msigdb_gobp
233,169,5,230,80,220,193
2393,80,1087,563,230,255,1265,1200,998,1096,648,2420,233,1608,885,1670,2485,1876,220,169,1556,1494,517,5,193,2135,2219,2092,763,670,1512,1698
-0.7208128794806824,1.6737888914174126,0.11832120737882174,0.47827985913265875,1.0064927423781989,0.9401810366079315,0.02063200139086309,0.053171452532358235,0.1835643251364057,0.11832120737882174,0.41263210835635755,-0.7527261533018542,1.0064927423781989,-0.14170409298657155,0.24889951105491837,-0.17409783001571622,-0.8482917188954088,-0.3034216261747569,1.039678116055493,1.20589568930337,-0.10928561936443627,-0.07684259325485089,0.5440142893653486,5.876636122044149,1.1393509612256292,-0.4644964320933728,-0.528740588862393,-0.432334116613742,0.3470721765493684,0.41263210835635755,-0.07684259325485089,-0.17409783001571622
2,771
Protein transmembrane transport
8
24
2.028282
0.042531
Q15629,P49755,P50542,Q9Y584,Q99595,O60830,O14925,O95831
Processes and pathways
GO Biological process
msigdb_gobp
262,319,69,202,201,102,41,46
41,813,102,770,1999,1468,46,421,1141,612,319,69,1156,1716,2019,1496,262,1063,1296,201,1453,1740,1024,202
2.1789293086297925,0.281601235173691,1.4728255311254135,0.31432550755588423,-0.40014526683647345,-0.07684259325485089,2.1451358481617295,0.6427760411067371,0.08573457717198472,0.4454450783260045,0.8077970614447516,1.7745094962795471,0.08573457717198472,-0.20646664342063079,-0.40014526683647345,-0.07684259325485089,0.9401810366079315,0.15093117770625794,0.02063200139086309,1.1061073370230785,-0.04437519590684744,-0.20646664342063079,0.1835643251364057,1.1061073370230785
2,771