term
stringlengths
2
121
overlap
int64
6
281
setsize
int64
7
499
score
float64
1.96
10.6
pval
float64
0
0.05
edge
stringlengths
41
1.97k
type
stringclasses
5 values
subtype
stringclasses
24 values
subtype_key
stringclasses
24 values
edge_idxs
stringlengths
11
1.17k
ann_idxs
stringlengths
19
2.31k
ann_vals
stringlengths
124
9.94k
sig_size
int64
2.2k
3.73k
Mitochondrial protein containing complex
42
140
1.991649
0.04641
O60830,P25705,P06576,Q99595,Q9NS69,O75964,O96008,O75306,Q16891,Q9Y5J9,P22695,O43676,P00846,Q13505,P13073,Q9NX14,Q9UDW1,P12235,Q8N4H5,Q9Y584,Q86Y39,O75947,P21796,P24539,Q9Y5L4,Q96CU9,Q6UXV4,O96000,Q9P0J0,P82933,P00403,Q9Y512,Q9NQ50,O75431,O14925,O14949,Q15388,P56385,P12236,Q567V2,Q5XKP0,Q9NX63
Localization
GO Cellular component
msigdb_gocc
0,129,386,5,8,142,529,526,411,548,406,33,35,41,169,565,48,436,53,56,311,570,64,443,586,453,324,198,200,579,207,472,340,342,464,92,222,351,474,96,239,505
1717,1061,464,92,33,1451,0,2174,526,342,910,570,142,2689,1721,626,1827,2379,198,529,207,35,726,386,2176,1170,2663,1393,1288,2556,1194,1612,436,474,169,1687,966,637,2447,628,64,1230,406,443,129,2560,2530,2219,1890,1776,1069,2241,2026,1198,2693,2385,2715,2665,2123,1807,708,1656,2363,2125,2161,351,2563,950,865,2543,1120,1623,2478,579,1055,761,41,2401,222,812,1534,411,1298,799,96,1410,2248,239,854,324,2103,2647,2492,311,2436,900,53,595,1130,2392,1812,453,2740,2617,781,2770,5,1100,2691,936,748,1247,2053,1385,2082,1541,1512,2016,340,634,8,680,565,505,1676,1306,200,48,1855,1334,1107,1387,1167,2377,961,472,56,548,586,909
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2,773
Organelle biogenesis and maintenance
23
83
1.990109
0.046579
P25705,P06576,O75964,A0AVF1,Q16891,P00846,O75935,P78371,O43924,Q92973,Q13505,P24539,Q6UXV4,Q96KP1,A6NIH7,O94927,Q9H6D7,O95684,O75431,Q10713,P56385,Q5XKP0,Q96A65
Processes and pathways
Reactome Pathways
msigdb_reactome
129,386,142,397,411,35,164,288,39,168,41,443,324,197,78,334,463,87,342,216,351,239,382
397,78,1717,2144,39,342,894,164,570,142,334,87,1859,35,1801,774,1091,386,1066,1366,1313,2381,1887,727,443,129,848,2323,1069,2241,1529,2693,1953,2400,1923,1863,1993,2629,591,756,2161,351,2577,864,794,850,2541,880,288,1054,896,216,1240,41,762,1014,2298,1056,2434,1268,714,763,1270,411,239,324,1597,1906,901,168,382,197,2508,1821,1849,2469,463,904,680,505,556,621,472
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2,773
Abnormal lower limb bone morphology
29
138
1.961201
0.049856
P50542,Q96HY6,O43505,O95831,Q9UHX1,P07602,O43924,P13073,P16278,Q15392,P08236,Q13510,Q08J23,P04062,P98175,O75844,Q14739,Q9Y487,Q9Y619,Q9NX62,Q10713,Q03164,P00813,Q15125,P16435,P21964,Q96A33,P06280,Q93009
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
273,281,154,30,161,37,39,169,43,50,306,52,309,65,323,70,204,211,213,90,216,95,226,230,250,242,243,122,252
538,1679,2650,1449,1222,2425,1770,1489,2654,154,39,2287,1108,2619,2115,342,483,70,557,402,403,1749,2238,30,2093,1524,1225,226,773,65,1549,122,37,1227,306,627,169,43,250,877,1754,603,862,2657,242,2698,2062,2217,2155,390,2323,2241,1691,2026,1152,2399,1398,273,1400,2585,2701,2363,2415,2637,2125,1657,323,95,760,639,2699,309,917,216,1757,2329,52,2047,2597,1839,204,1809,2700,230,50,533,2419,459,2005,1350,1965,1627,664,2742,764,2225,2165,582,429,2493,2227,1846,1099,2438,252,243,584,281,1275,1974,1817,1444,1818,504,2470,1486,1333,1215,904,2259,2442,1138,2512,90,821,546,161,556,1253,2514,2235,211,1468,1944,1335,752,2726,213
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2,773
Transporter activity
30
129
4.380357
0.000012
O60830,Q99595,Q9NS69,O00400,O96008,Q9HD20,Q8WTV0,O43772,P38435,P21281,P08183,Q9UBX3,Q8IXU6,Q99808,Q5T1Q4,Q96H78,P21796,Q00535,P45880,Q9H2D1,Q8TB61,O43676,O15173,Q6N075,O43808,O43681,O75964,Q70HW3,P41440,P53985
Functions
GO Molecular function
msigdb_gomf
0,1,2,6,255,138,16,17,269,266,20,149,23,154,29,30,28,165,41,43,175,51,73,214,210,209,95,99,240,114
1288,1239,6,1289,1190,73,2273,51,209,17,210,0,1675,1804,1380,1102,1194,848,1466,95,1592,778,1467,887,2198,291,2254,255,634,265,663,1419,1718,2120,1505,636,20,1679,637,1854,434,1548,1595,1018,2176,981,1722,266,816,28,1723,706,2121,1469,2102,1683,1554,269,1389,240,41,2351,340,673,2411,744,2425,2104,942,1516,1993,114,1257,1026,524,709,1206,2314,365,1477,165,1954,712,1077,829,1958,753,715,1613,2025,1219,29,214,1042,2242,99,23,1662,1174,175,16,834,1044,30,1828,1783,2005,1133,1,1047,154,1750,2361,1930,2393,43,958,1137,138,2,149,1324,689,965,332,966,967,1189,468
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2,448
Transmembrane transport
35
152
4.069615
0.000047
O60830,Q99595,Q9NS69,O00400,O96008,Q9UHG3,Q06481,Q9HD20,O75844,Q8WTV0,O43772,P38435,P21281,P04062,P08183,Q9UBX3,Q8IXU6,Q99808,Q5T1Q4,Q96H78,P21796,P0DP25,Q00535,P45880,Q9H2D1,Q8TB61,Q99523,O43808,P78417,P05067,O75964,Q70HW3,P23786,P41440,P53985
Processes and pathways
GO Biological process
msigdb_gobp
0,1,2,6,255,9,137,138,12,16,17,269,266,265,20,149,23,154,29,30,28,280,165,41,43,175,190,210,91,220,95,99,110,240,114
1288,2195,1239,6,1289,1190,774,1464,17,210,1015,0,1675,1590,1804,1890,848,12,1293,1466,95,1592,887,291,470,255,634,265,663,1419,220,1718,1640,2120,1505,433,636,20,1679,637,280,1854,2344,353,434,1548,1595,1018,435,981,1722,266,816,2100,28,110,706,2121,1388,475,1469,1895,355,1683,1510,1068,1554,269,1389,240,41,1899,2351,673,439,744,2425,674,1993,114,789,1517,1257,1026,524,2313,1347,709,1206,746,91,1477,165,1954,712,647,1692,137,713,1077,2055,589,829,753,715,1613,2416,1361,29,1042,2242,950,99,2107,23,1174,175,1968,16,913,834,30,1090,1828,2334,190,1,1831,1047,154,2361,1096,2393,43,958,1137,1978,138,2,149,1324,964,9,689,965,1053,332,967,1005,658,1842,468
-0.10674096394992204,-0.9355777762145688,-0.07550814716240413,4.17639495057996,-0.10674096394992204,-0.04450929815907613,0.2532540711162199,-0.23407485992918883,3.6850112480094657,1.0567243347808781,0.07720648685986563,5.4909975245049525,-0.3988970237964776,-0.3321900474773907,-0.5009758947381806,-0.570418912354578,0.1954125848637109,3.815266225617852,-0.10674096394992204,-0.23407485992918883,1.8183207085661213,-0.3321900474773907,0.1661804150958811,0.8398590107348664,0.5306450322137474,0.9135017799843423,0.3665164111684586,0.8891085200681355,0.33849725070930553,-0.20187454584837183,1.0332193663097253,-0.4326504272995773,-0.3654114610118159,-0.8227493700904442,-0.2665252615044035,0.5838892489081151,0.3665164111684586,3.629123698076312,-0.3988970237964776,0.3665164111684586,0.8645614974599019,-0.535555719910308,-1.2926450388735131,0.7139531433521713,0.5838892489081151,-0.29922916393356874,-0.3321900474773907,0.07720648685986563,0.5838892489081151,0.10708006863031112,-0.4326504272995773,0.8891085200681355,0.2244362755490974,-0.7857834156318783,3.3953239924028624,1.661989469315608,0.31028208638028104,-0.8227493700904442,-0.16992097114184565,0.5306450322137474,-0.23407485992918883,-0.570418912354578,0.7139531433521713,-0.3988970237964776,-0.2665252615044035,0.047113613573717794,-0.29922916393356874,0.8891085200681355,-0.16992097114184565,0.9618336856730934,2.9411724327983952,-0.570418912354578,-1.3341605680714537,0.33849725070930553,0.5838892489081151,0.28186851004785385,-2.2560739912554033,0.33849725070930553,-0.6410118115887157,1.6218490896718054,0.2532540711162199,-0.2665252615044035,-0.07550814716240413,0.07720648685986563,0.4766797433412753,-1.1703784526483574,-0.13821085131774094,0.31028208638028104,-0.04450929815907613,0.28186851004785385,1.8563844902450153,-0.23407485992918883,1.2397552982334583,-0.6055695540857844,0.31028208638028104,0.3665164111684586,-0.3988970237964776,1.4143866320634981,0.31028208638028104,0.047113613573717794,-0.7127882759896713,0.4219761463810362,0.2244362755490974,0.28186851004785385,0.31028208638028104,-0.3321900474773907,-2.007660709981407,-0.13821085131774094,3.3953239924028624,0.07720648685986563,-1.0124550937073367,0.13673713573536073,1.7798568211263002,-0.7857834156318783,3.526002825244512,-0.013741371797105306,1.1948121451525973,-0.6055695540857844,3.7180796333138844,0.1661804150958811,0.2244362755490974,3.3953239924028624,0.047113613573717794,-0.5009758947381806,-1.2107600767809958,1.1493334889520355,5.020390698192011,-0.5009758947381806,0.07720648685986563,1.3061897616761267,-1.4183692792800806,0.047113613573717794,-1.6360731710669292,2.870946367764477,0.13673713573536073,0.016798620797514572,-0.6055695540857844,1.4143866320634981,4.61621113583267,1.3280784620023343,-0.10674096394992204,0.13673713573536073,4.060626666237823,0.33849725070930553,0.13673713573536073,0.07720648685986563,0.7648013431550654,0.13673713573536073,0.10708006863031112,0.3665164111684586,-0.5009758947381806,0.5573562198457855
2,448
Predicted membrane proteins
98
382
3.905707
0.000094
O60830,Q99595,Q9NS69,Q9H6V9,O00400,Q8N0U8,O75844,P24390,O60725,Q8WTV0,O43772,Q9BQE5,Q96G23,P08183,P30519,Q8IXU6,Q5BJF2,Q5T1Q4,Q96H78,Q8N511,Q8NCC3,Q16850,O43169,Q99720,Q86XL3,Q567V2,O43676,O43657,O95197,P42892,P37268,Q8NBX0,Q15392,Q7Z2K6,P43307,Q8TCT9,Q9Y282,P20645,O15173,P35613,Q92859,P27544,Q06136,Q9BRX8,Q9NR77,Q14739,P67812,Q86YN1,O75964,Q9UIQ6,O96005,Q70HW3,O60637,Q6UW68,Q96A26,Q9BTX1,Q9UBM7,P53985,Q14108,Q96N66,P09601,Q8TBQ9,Q06481,Q9HD20,O75352,Q9BVK6,O95470,Q9UBX3,Q99808,Q9NPA0,P49257,Q9BUN8,Q9UJ14,Q92804,Q8TB61,Q8IWA4,Q70UQ0,Q8IV08,Q92896,Q6ZXV5,P16435,Q99523,Q9Y2U8,Q9UIA9,Q14574,Q5KU26,Q9NQC3,Q9HD45,Q9NR28,Q6N075,P51648,O43808,P05067,Q9Y5M8,Q15904,P41440,Q96KC8,Q99590
Functions
Protein Atlas Protein class
protein_atlas_protein_class
0,1,2,3,6,7,12,13,15,16,17,18,21,20,22,23,24,29,30,31,32,33,34,36,39,40,51,53,54,56,59,61,64,65,66,68,71,72,73,74,75,76,77,78,81,82,90,93,95,96,97,99,104,106,107,108,112,114,118,124,129,136,137,138,144,146,147,149,154,158,159,169,171,176,175,174,181,182,183,180,186,190,196,195,193,200,202,205,215,214,212,210,220,237,233,240,244,245
2144,359,1238,2096,417,6,322,1709,1289,2272,1010,1710,469,771,1413,697,2118,542,431,73,731,2099,1981,1711,34,360,1803,53,2273,51,17,210,493,1759,2077,104,15,0,1675,290,1380,144,2402,1846,1938,1939,324,12,1503,1293,95,519,777,2197,1592,778,54,887,1806,147,291,1717,279,470,97,1504,2304,634,635,497,662,1243,889,663,1419,220,1718,1640,813,20,1679,637,129,2355,520,1547,1064,1645,472,434,1548,1595,1197,890,186,1018,1425,2200,981,72,817,13,706,76,1250,1469,22,311,1990,1510,2122,1648,74,1341,59,269,1684,240,56,1858,66,1023,984,1114,159,673,2079,1344,1306,1073,212,744,2425,1651,2366,1687,114,1517,1257,1026,1346,644,1258,504,2313,505,1206,2181,791,90,1477,1075,2125,712,77,2317,137,327,1398,1441,864,828,1036,1263,829,441,1216,118,2156,1821,2279,193,82,1656,1963,870,1965,715,64,443,1823,1613,233,616,1266,1219,33,1696,282,1361,2280,1446,510,40,24,1268,368,2135,717,200,1363,29,831,1220,1871,214,463,1311,2242,1918,1618,106,1312,1450,404,180,99,181,65,1224,1043,1489,1777,39,2333,874,875,93,182,174,1873,2189,23,1127,954,7,426,31,1365,1273,1172,1662,61,274,32,1569,1174,757,175,136,68,1744,16,406,1274,594,595,1664,1366,1875,512,176,75,183,1044,464,2360,720,107,427,1526,1455,2066,1747,21,30,876,1748,244,124,1828,1046,1783,1667,683,1278,389,596,190,1133,245,1,36,2392,2111,154,2248,2295,18,78,1180,1531,534,108,169,515,2361,146,516,2393,1880,2165,1533,262,331,2268,2321,253,685,485,2389,3,958,1137,922,138,205,1534,1581,158,202,215,81,2,723,2363,1881,537,1703,375,765,2426,2168,2116,883,1535,2298,1584,112,488,962,149,1324,2012,195,96,171,350,332,1184,2349,394,321,71,843,2413,196,1798,467,1098,1412,1460,1139,1189,1007,1842,237,2041,1286,1757,2075,1058
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2,448
Transport of small molecules
30
121
3.788903
0.000151
Q9UL46,P09601,P07237,O00400,Q9HD20,Q8WTV0,P21281,Q92530,P08183,P30519,Q9UBX3,P10644,P60900,Q99808,P21796,P49721,P45880,Q9BUN8,Q8TB61,P28072,P35613,P28074,Q99436,P02656,Q70HW3,P28070,Q15904,P20618,P53985,Q10713
Processes and pathways
Reactome Pathways
msigdb_reactome
128,129,256,6,138,16,266,148,20,22,149,151,152,154,28,38,41,169,175,48,74,87,223,226,99,98,233,239,114,126
451,845,6,1674,604,264,1675,1890,973,2078,1195,1294,887,2145,226,497,663,1419,1718,664,256,20,1679,1149,129,151,434,1548,1198,1018,435,979,981,548,239,266,816,28,667,354,1109,549,1022,98,48,87,1469,22,355,1813,1112,74,1511,298,2446,1389,1434,41,1201,1392,38,341,744,2425,1994,114,1517,1257,1074,1731,152,708,709,2314,526,1436,1437,1261,587,1608,1351,750,126,1441,828,1264,650,1613,233,2242,99,907,996,1174,175,16,913,148,1875,1044,1625,1278,223,596,1831,1047,154,169,958,138,962,149,392,689,1053,128,841,430,967,1189,1842
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2,448
Transporter
32
144
3.671494
0.000241
Q8TAG9,P54105,O00400,O96008,P24390,O43772,Q9BQE5,Q9BVK6,P21281,P08183,Q9UBX3,Q8IXU6,Q99808,Q5T1Q4,Q96H78,P49257,P61923,O95563,Q9H2D1,Q8TB61,Q8NFH4,Q99523,Q9UIA9,Q96S59,Q9HD45,Q6N075,O43808,P48739,Q70HW3,P41440,P53985,Q9NZZ3
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
131,258,6,255,13,17,18,146,266,20,149,23,154,29,30,159,294,291,43,175,317,190,195,329,205,214,210,340,99,240,114,263
2096,2195,844,6,1539,1328,2301,2042,1463,1711,17,210,1193,379,336,931,1675,1143,848,1466,1716,887,1806,544,291,455,255,663,1419,1718,2120,20,1679,1149,1247,1645,434,1548,1197,1018,981,266,816,13,706,2121,1469,1251,582,1554,1389,240,893,340,159,673,1073,1651,707,1727,1993,1203,1256,1994,114,1730,258,1517,675,1257,1026,524,988,709,1206,294,1261,365,1477,1351,1075,712,1693,898,899,864,1610,649,679,1121,1265,715,1613,29,214,1042,2242,99,719,875,23,426,317,131,175,1744,481,1969,833,513,1044,446,1277,2211,30,1828,621,329,190,1133,2111,154,18,1928,146,43,958,1137,205,263,1535,1585,149,689,195,965,1184,1375,806,1098,1189,601,693,1058
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2,448
Nuclear outer membrane endoplasmic reticulum membrane network
55
225
3.609656
0.000307
P09601,O00400,Q8N0U8,P07099,O75844,P24390,Q9HD20,O60725,O75352,Q9BQE5,Q9BVK6,Q96G23,O95470,P30519,Q5BJF2,P26885,Q9NPA0,Q04323,Q8N511,P49257,Q16850,Q99720,Q86XL3,Q9BUN8,P48449,Q8TB61,Q70UQ0,Q8IV08,O95197,P16435,P37268,Q99523,Q15392,Q7Z2K6,P43307,Q8NFQ8,Q8TCT9,O75340,Q9Y282,P35613,Q9NQC3,P27544,Q06136,Q9UBF8,P61586,Q14739,P51648,P67812,Q86YN1,Q9Y5M8,Q15904,Q9UBM7,Q96KC8,Q14108,Q96N66
Localization
GO Cellular component
msigdb_gocc
129,6,7,11,12,13,138,15,144,18,146,21,147,22,24,27,158,155,31,159,33,36,39,169,42,175,181,182,54,186,59,190,64,65,66,194,68,197,71,74,202,76,77,206,79,82,212,90,93,237,233,112,244,118,124
2144,359,417,6,418,1709,469,2042,697,2118,1588,2099,1981,927,2390,732,2077,1014,15,1985,197,144,1846,12,1293,396,1195,1716,54,1806,147,544,1717,279,1504,2304,635,662,1243,889,352,1332,11,1643,1941,129,520,1680,186,1018,1425,1151,1723,817,13,27,76,1110,1250,1111,2177,22,355,640,1510,582,74,59,269,1684,1252,1991,66,984,893,42,340,159,2123,673,1992,1344,1073,212,1651,707,1203,1256,1730,1731,644,1258,2313,1028,1204,248,989,1394,1205,2081,79,1206,2181,294,1770,862,90,1520,2126,2440,155,77,327,1077,1116,1441,864,1216,118,1821,2279,82,1963,869,1122,1965,64,328,1823,233,33,510,24,1268,368,1220,1871,463,2282,1311,2242,1312,1450,181,65,1489,1777,39,2333,93,182,2107,7,31,1365,1273,1172,757,194,1228,175,1920,1968,68,1176,1744,1969,1087,464,2360,427,1526,1455,21,1090,1575,244,124,1046,1783,190,36,2392,2248,18,1180,169,2361,146,2393,685,2034,922,138,1581,158,202,320,723,2426,2116,883,1535,1584,1585,206,112,962,1324,1933,332,656,71,1885,467,1327,1098,1673,539,601,237,1757,693,2075,769
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2,448
Ion transmembrane transport
24
112
3.490635
0.000482
O00400,Q9UHG3,Q9HD20,O75844,O43772,P21281,P08183,Q9UBX3,P21796,P0DP25,Q00535,O95563,P45880,Q9H2D1,Q8TB61,Q9UM00,O43808,P78417,P05067,O75964,P30626,Q70HW3,P41440,P53985
Processes and pathways
GO Biological process
msigdb_gobp
6,9,138,12,17,266,20,149,28,280,165,291,41,43,175,332,210,91,220,95,355,99,240,114
1239,6,1289,1190,1464,17,210,1015,1675,1590,1804,1890,848,12,1293,1466,95,887,291,634,663,1419,220,1718,1640,2120,1505,433,636,20,1679,637,280,1854,353,434,1548,1595,1018,435,981,1722,266,816,2100,28,706,2121,1388,475,1895,355,1683,1068,1554,1389,240,41,1899,2351,439,744,2425,1993,114,789,1517,1257,1026,524,709,1206,746,91,1477,165,712,647,713,1077,2055,589,829,753,1613,99,2107,1174,175,913,834,1090,1828,2334,1831,2361,43,958,1137,138,149,964,9,689,965,1053,332,967,1005,658,1842,468
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2,448
Ion transport
35
147
3.357176
0.000787
P54105,O00400,O96008,Q9UHG3,Q9HD20,O75844,Q02790,O43772,P21281,P08183,Q9UBX3,Q99808,P21796,P0DP25,Q00535,O95563,P45880,Q9H2D1,Q8TB61,P07602,Q9UM00,O15173,P61586,Q6N075,O43808,O43681,P61201,P78417,P14174,P05067,O75964,P30626,Q70HW3,P41440,P53985
Processes and pathways
GO Biological process
msigdb_gobp
258,6,255,9,138,12,141,17,266,20,149,154,28,280,165,291,41,43,175,185,332,73,79,214,210,209,342,91,89,220,95,355,99,240,114
2096,1239,6,418,1289,1190,73,209,1464,17,210,1015,1675,1590,1804,886,1890,848,12,1293,1466,95,887,291,255,634,497,888,663,1419,220,1718,1640,2120,1505,433,185,636,20,1679,637,280,1854,1064,353,434,1548,1595,521,89,2277,1018,435,474,981,1385,1722,266,816,2100,28,706,2121,1388,475,1469,1895,355,1683,608,1553,1068,1554,1389,240,41,1470,1899,2351,439,744,2425,1651,1993,114,258,789,1517,1257,1026,524,342,709,79,1206,746,91,1477,165,1351,141,712,647,713,1077,2055,589,829,753,1122,1613,1219,214,1042,2242,99,2107,1174,175,913,834,1090,1828,1783,2334,1831,154,2361,1579,43,958,1137,138,149,964,9,689,965,1053,332,1235,768,967,1005,658,1842,468
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2,448
vesicles
35
117
3.283811
0.001024
O00400,Q06481,O95470,P21281,Q8IXU6,P17812,P49257,O95674,P61923,Q8N6T3,P48449,O00429,O00264,Q96AX1,P50570,P17612,Q15392,O15127,Q9UM00,Q15436,O15173,Q06136,Q9UBF8,P61586,Q9Y5X3,O43808,O15144,O60749,O96005,P11413,Q15904,P20339,P41440,P53985,Q10713
Localization
OpenCell Localization
opencell_localization
6,137,147,266,23,281,159,279,294,296,42,418,417,446,439,435,64,431,332,328,73,77,206,79,216,210,208,336,97,353,233,238,240,114,126
417,6,418,469,2042,1190,1331,542,431,208,2097,73,731,2099,1711,699,210,1100,336,1846,1716,1806,147,279,97,2304,497,662,663,1245,1149,1247,1645,353,1197,435,281,981,238,266,1723,1553,1389,240,1252,941,42,159,673,1072,439,1766,2425,1256,114,1730,675,505,989,1394,1205,611,709,79,294,1953,1261,1351,77,137,126,1263,1611,649,1120,2265,1265,796,64,328,1823,1613,233,1483,1169,875,23,1127,954,1699,296,757,1178,1044,464,916,446,1746,2211,621,1576,1930,2393,763,1581,1535,1585,206,689,1838,332,1839,1325,1184,1460,216,693
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2,448
Organelle subcompartment
63
263
3.032431
0.002426
P09601,O00400,Q8N0U8,P07099,O75844,P24390,Q9HD20,O60725,O75352,P38435,Q9BQE5,Q9BVK6,Q96G23,O95470,P30519,P04062,Q5BJF2,P26885,Q9NPA0,Q04323,Q8N511,P49257,Q16850,O95674,Q99720,Q86XL3,Q9BUN8,P48449,Q8TB61,P40616,Q70UQ0,Q8IV08,O95197,P16435,P37268,Q99523,Q15392,Q7Z2K6,P43307,Q8NFQ8,Q8TCT9,O75340,Q9Y282,P20645,P35613,Q9NQC3,P27544,Q06136,Q9UBF8,P61586,Q14739,P51648,P67812,Q86YN1,P05067,Q9Y5M8,Q15904,Q9UBM7,Q96KC8,Q14108,Q96N66,P61009,Q10713
Localization
GO Cellular component
msigdb_gocc
129,6,7,11,12,13,138,15,144,269,18,146,21,147,22,265,24,27,158,155,31,159,33,279,36,39,169,42,175,172,181,182,54,186,59,190,64,65,66,194,68,197,71,72,74,202,76,77,206,79,82,212,90,93,220,237,233,112,244,118,124,248,126
2144,359,417,6,418,322,1709,469,2042,1413,697,2118,542,431,2099,1981,927,2390,929,1541,732,2077,1014,15,1985,931,197,144,1846,811,12,1293,396,1195,1716,54,1806,736,147,544,1717,279,1504,2304,635,265,662,1243,889,220,352,11,1643,1941,1149,1247,129,520,472,1680,186,1018,1425,1151,72,2100,1723,817,13,27,76,1110,1250,2286,1111,2177,22,355,640,1510,582,74,59,269,1684,172,1252,66,1470,984,893,42,340,159,2123,673,1344,439,1073,212,1651,707,1203,1256,1730,1731,644,1258,2313,1028,1204,2019,248,989,1394,1205,2081,79,1206,2181,294,1770,862,90,711,1520,1351,1075,2126,2440,155,77,327,1077,2408,1693,1116,898,126,1441,864,1216,118,1821,2279,82,1656,1121,1963,869,1122,1965,64,328,1823,233,33,510,24,1268,368,1220,617,1871,463,2282,1311,2242,1312,1450,181,65,1489,1777,39,2333,93,182,2292,2107,7,31,1365,1273,1172,1173,757,194,1228,175,1920,1968,68,1744,1969,1621,1178,1087,464,2360,427,1526,1455,21,1090,1575,244,124,1046,1783,190,36,2392,2248,2295,18,1180,169,2361,146,1181,410,2393,685,2034,922,138,1581,158,202,2250,320,723,2426,2116,883,1535,1584,1585,206,112,962,1324,1796,1933,332,1184,656,1375,71,806,1885,467,1327,1098,1673,539,237,2074,1757,693,2075,769
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2,448
Mitochondrion organization
29
138
3.023035
0.002503
O60830,Q99595,Q9NS69,Q6DKK2,O75153,Q5TC12,O96008,Q5JRX3,P04062,O75223,P21796,P49257,P0DP25,Q00535,P45880,Q8IWA4,O43676,P48506,P55786,P27544,P14406,O00170,Q99536,O14737,Q96A26,Q15785,Q8N4H5,Q9H3K2,Q10713
Processes and pathways
GO Biological process
msigdb_gobp
0,1,2,260,4,134,255,272,265,150,28,159,280,165,41,174,51,187,63,76,84,217,103,229,107,241,119,253,126
217,844,418,229,2014,774,2273,51,1378,0,4,150,1804,1380,1381,1890,1194,973,1503,1592,778,887,2198,470,2254,255,1146,497,265,2174,1637,1718,576,1644,1761,280,2344,1893,434,84,2048,28,76,1388,2102,1552,1895,891,857,1813,2311,1431,2345,2018,41,187,159,2079,1471,1306,1767,1073,2104,674,63,1028,364,1115,165,1521,1077,126,1611,441,901,1868,715,241,871,2025,1219,1267,1361,1447,272,1362,134,2062,260,1043,874,174,1873,2189,2418,1490,1661,119,1365,1174,1175,1968,913,107,1320,621,1278,2334,103,1,1831,2375,1047,920,1095,1406,1135,253,2143,1978,304,2,1671,413,1881,839,349,1703,358,1323,655,2012,599,1053,2194,1842,692,1058
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2,448
Endoplasmic reticulum
80
362
2.734273
0.006252
Q9H6V9,O00400,Q8N0U8,Q9UQB8,P07099,O75844,P24390,Q9UMX5,O60725,Q9BQE5,Q96G23,P30519,Q5BJF2,P26885,Q8N511,Q16850,Q99720,P80303,Q86XL3,P48449,Q02818,O95197,P37268,Q15392,Q7Z2K6,P43307,P10619,Q8TCT9,Q9Y282,O15173,P35613,P27544,Q06136,P61586,Q14739,P67812,Q86YN1,Q9UBM7,Q14108,Q01105,Q96N66,P09601,Q06481,Q9HD20,O75352,Q9BVK6,O95470,Q92530,Q96AY3,Q9NPA0,Q04323,P49257,Q9BUN8,Q8TB61,Q70UQ0,Q8IV08,Q6ZXV5,P16435,Q99523,Q8NFQ8,O75340,P23396,Q9NQC3,Q9UBF8,Q9UNW1,P51648,O43681,P05067,O75718,Q9Y5M8,Q15904,Q96KC8,P61009,P07237,O15498,P38435,P04062,P55145,O95674,P61923
Localization
GO Cellular component
msigdb_gocc
3,6,7,10,11,12,13,14,15,18,21,22,24,27,31,33,36,37,39,42,49,54,59,64,65,66,67,68,71,73,74,76,77,79,82,90,93,112,118,122,124,129,137,138,144,146,147,148,153,158,155,159,169,175,181,182,180,186,190,194,197,198,202,206,207,212,209,220,218,237,233,244,248,256,254,269,265,270,279,294
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2,448
Cation transport
30
111
2.680314
0.007355
P02786,O00400,Q9HD20,O75844,Q02790,O43772,P21281,P13693,Q99808,P21796,P0DP25,Q00535,O00429,P50570,P17612,P12235,P07384,Q9UM00,O15173,P61586,O43808,P61201,P78417,P05067,O75964,P30626,Q70HW3,P11413,P17931,P28161
Processes and pathways
GO Biological process
msigdb_gobp
497,6,138,12,141,17,266,521,154,28,280,165,418,439,435,434,433,332,73,79,210,342,91,220,95,355,99,353,474,475
2096,6,418,1289,1190,73,1464,17,210,1015,1675,1804,886,1890,12,1466,95,887,634,497,663,1419,220,1718,1640,2120,1505,433,636,1679,637,280,1854,1064,353,434,1595,521,2277,1018,435,474,981,1385,1722,266,816,2100,28,706,2121,1388,475,1895,355,1683,608,1553,1068,1554,1389,1470,1899,2351,439,744,1651,789,1517,1257,1026,524,342,709,79,1206,746,91,1477,165,1351,141,647,713,1077,2055,589,829,1613,1219,99,2107,1174,913,834,1090,1828,2334,1831,154,958,1137,138,964,689,1053,332,1235,768,1005,1842
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2,448
Metabolism of lipids
36
139
2.66798
0.007631
Q15165,Q9UMR5,P38435,O43772,O95470,Q96G23,P04062,Q8NCC3,Q16850,O95674,P48449,P49748,Q9H7Z7,Q9NPH0,Q14914,Q8IV08,Q8N8N7,Q9BWD1,P37268,P07602,Q15392,P10619,P27544,Q06136,Q9UBF8,Q14739,P51648,P50897,O43808,O43681,P23786,P20339,Q9UBM7,P09960,Q96N66,Q10713
Processes and pathways
Reactome Pathways
msigdb_reactome
8,139,269,17,147,21,265,32,33,279,42,44,45,47,173,182,57,58,59,185,64,67,76,77,206,82,212,211,210,209,110,238,112,120,124,126
2144,729,970,2219,469,489,1802,2099,1981,209,17,210,2077,1193,734,2303,1806,147,544,1717,279,1504,265,2439,1639,1016,1244,185,2306,2222,120,67,2438,1335,739,2403,1549,435,2048,238,1597,1723,1550,2017,110,2309,76,2350,1510,293,2311,59,269,1725,2050,2018,2259,42,340,822,44,211,212,1604,1993,987,1687,1730,2080,1473,644,1205,2124,2261,612,2182,1954,2020,77,126,2433,590,1354,82,173,1121,614,8,615,64,328,1822,1823,798,33,754,2280,510,1447,1871,1312,873,182,57,1172,1315,32,757,1274,21,124,1972,2005,484,1830,1529,1750,2248,1180,2267,58,921,2393,45,47,1628,623,723,2426,2116,883,1535,206,112,2432,350,139,1283,1459
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2,448
Lipid biosynthetic process
22
107
2.630358
0.00853
Q8WTV0,O95470,Q96G23,Q8NCC3,Q16850,P48449,P49748,Q9H7Z7,Q9NPH0,P16435,P37268,Q8NBX0,Q15392,P27544,Q06136,Q9UBF8,Q14739,P14174,Q86YN1,Q9UBM7,Q96N66,Q10713
Processes and pathways
GO Biological process
msigdb_gobp
16,147,21,32,33,42,44,45,47,186,59,61,64,76,77,206,82,89,93,112,124,126
729,970,2219,469,489,1802,2099,1981,378,1985,811,1502,1195,147,1717,279,1545,1504,2304,226,265,888,663,2306,353,456,89,1335,739,2403,186,1809,1723,1550,2017,2309,76,475,1469,1510,59,2436,1252,2018,42,822,44,987,1687,894,2203,644,1954,2020,77,126,2433,590,1354,82,615,64,716,1822,1823,1869,33,2280,510,1447,1871,1312,93,1315,61,32,757,16,1274,1130,21,124,804,1046,2005,1529,2375,2111,2248,515,1834,1879,921,391,45,47,959,723,2426,2116,883,1535,206,112,964,766,2093
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2,448
Golgi apparatus
35
116
2.564012
0.010347
P09601,Q5BKZ1,Q8TEY7,Q8NC54,P24390,O00178,Q8IXU6,P55327,Q6ZRP7,Q8N6T3,P80303,O75071,P36404,P40616,Q02818,Q92896,P50570,P46926,Q99523,O15127,Q8N4Q0,Q5KU26,Q92859,Q9HD45,Q9UBF8,O00461,O00231,P50897,Q9HB40,P67812,P05067,O60637,A1L0T0,Q6P6C2,Q9H3P7
Localization
Protein Atlas Subcellular
protein_atlas_subcellular_location_all
129,387,275,274,13,143,23,401,404,296,37,290,298,172,49,183,439,438,190,431,70,200,75,205,206,322,451,211,92,90,220,104,359,251,391
359,143,844,451,322,2042,1331,431,452,731,1889,2390,1414,2077,104,931,2364,290,1101,700,1715,1544,1504,662,220,1641,129,1420,472,1549,1723,13,853,937,1153,1814,582,298,172,1470,438,893,673,439,1306,211,1515,1202,1203,1256,401,90,37,711,1478,49,2408,1693,1116,898,2429,901,1656,387,200,1362,1168,1917,2282,1311,251,404,1775,1776,1170,907,875,2292,1698,23,954,70,1699,296,274,1176,2086,275,1178,75,183,834,1044,916,998,2005,190,597,1577,1878,1930,391,1495,1322,92,205,2250,1371,723,206,2012,1796,1282,2413,2401,693
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2,448
Endoplasmic reticulum
32
157
2.501424
0.01237
P07237,Q8N0U8,O75352,O95470,Q96G23,P55145,Q5BJF2,Q9NVZ3,P49257,O95674,Q16850,O43169,O15460,Q86XL3,Q9BUN8,Q70UQ0,Q9H3G5,Q8IV08,O95197,Q96CN7,P37268,P43307,Q8TCT9,P23396,Q9NQC3,P27544,P51648,O96005,Q6UW68,Q9UBM7,Q96KC8,Q8WUJ1
Localization
Protein Atlas Subcellular
protein_atlas_subcellular_location_all
256,7,144,147,21,270,24,286,159,279,33,34,289,39,169,181,52,182,54,318,59,66,68,198,202,76,212,97,106,112,244,127
416,417,469,2118,2099,289,34,927,2390,732,144,1293,396,1195,54,1806,147,279,97,2304,1243,889,1678,1640,256,1062,1546,638,1646,666,815,1680,1107,1425,1108,1721,548,2148,851,2149,198,936,76,1509,1110,1250,551,2177,1300,1990,582,1898,59,1684,552,66,787,983,1070,1157,1343,985,1391,159,1344,1817,2365,1073,212,270,2313,1606,1652,1952,790,1206,2181,1396,990,1903,527,1348,1518,1029,528,2225,1953,2204,896,2358,1476,1209,1259,477,2054,507,826,613,1075,1733,1441,1352,2023,356,1216,386,2279,2084,1965,1402,443,1823,33,24,1311,1083,106,1312,181,1489,1777,39,2333,182,7,1365,1491,757,68,910,127,427,1526,318,1455,21,1575,244,1783,2392,2248,1180,169,52,685,922,202,428,286,2116,883,1535,1584,112,1324,332,657
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2,448
Vesicle membrane
56
176
2.399362
0.016424
P02786,Q13576,O15498,Q06481,P24390,Q9BXS5,Q8WTV0,P35237,P62993,O43924,P30519,P10321,Q9NVZ3,Q8N511,P49257,P0DP25,P61923,P42785,Q9NR31,Q9H4M9,P10253,Q9Y6G9,O00429,O00264,O15126,Q8IV08,Q96AX1,P42892,P07602,P50570,Q92599,Q99523,O15127,O75340,Q15436,P20645,Q5KU26,P35613,Q07065,Q9Y696,O00461,P61586,Q9Y5X3,Q9H223,O95721,Q969Q5,O60749,Q9UIQ6,P30626,P11717,P17931,Q15904,P20339,Q9BV23,Q14108,Q9NZZ3
Localization
GO Cellular component
msigdb_gocc
497,385,254,137,13,410,16,268,529,19,22,520,286,31,159,280,294,35,428,566,422,571,418,417,542,182,446,56,185,439,189,190,431,197,328,72,200,74,327,468,322,79,216,347,455,88,336,96,355,472,474,233,238,515,118,263
1287,1462,2096,844,417,418,322,2042,1463,1413,542,431,1711,254,699,929,1541,19,1100,1015,1193,336,931,734,197,886,1846,1143,811,1294,1716,544,455,2145,635,497,888,662,1640,1505,185,636,1149,1247,280,422,520,1150,1893,1645,472,1197,740,474,981,1151,1385,238,72,817,13,1110,2177,22,355,268,582,74,1684,1433,35,56,1513,893,159,673,439,1255,1766,744,1651,1203,1256,1994,1730,1257,2019,1394,1205,709,79,294,1953,529,1261,2263,1520,1351,1954,137,327,898,2227,385,649,118,1821,1356,1120,2265,1265,796,328,2328,233,200,831,1917,872,875,182,31,757,16,595,833,189,1044,88,446,1625,1781,2211,1368,621,2005,190,1529,2111,684,1750,1927,515,1930,410,1096,347,566,1581,428,286,263,1535,961,924,1585,1458,96,1796,1933,1838,1839,1325,966,768,1184,2413,1056,1098,1189,2074,216,693,468,571,770
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2,448
Adaptive immune system
66
149
2.321021
0.020286
Q9UL46,P19474,P41240,Q9UJX4,P01889,Q9BXS5,P62993,Q14139,Q92530,O43242,Q8TBC4,P10321,P60900,P30260,P62191,O94874,Q15386,P61086,Q9UJX2,Q14203,P49721,P25786,Q9Y6G9,P04439,P61088,P28072,O95486,P30153,Q16763,P25789,Q13617,P50570,P63104,Q13867,Q9UJW0,P17612,P55786,O75935,P10619,Q99460,Q15436,Q5KU26,P63208,P52732,P61163,O00231,P09429,P28074,Q99436,Q92990,P51665,Q9UIQ6,Q13409,Q9Y4B6,P52888,P28070,P25787,O14818,A0AVT1,P33176,P20618,P61081,P68036,Q15008,Q9ULT8,Q9BUF5
Processes and pathways
Reactome Pathways
msigdb_reactome
128,130,642,278,635,410,529,678,148,264,405,520,152,26,526,396,403,402,690,295,38,667,571,662,301,48,544,670,445,549,714,439,440,314,60,435,63,432,67,596,328,200,587,326,586,451,577,87,223,620,341,96,356,626,227,98,354,604,602,608,239,610,364,650,393,390
602,1800,2096,451,845,1674,604,926,264,929,1846,973,432,2197,396,1294,1716,1760,1853,544,2145,635,662,1640,577,1149,520,67,435,979,130,239,817,667,354,1109,549,1110,1250,1022,98,48,87,1724,2177,670,1154,26,982,608,1511,642,1252,1434,2356,941,1201,1392,38,439,1766,1073,341,326,227,859,1994,1730,1074,63,2313,152,1204,610,402,301,586,708,1206,526,1436,1437,529,1261,440,2263,587,364,710,1351,2379,1692,750,947,898,865,828,356,992,1264,714,993,314,2155,678,295,1400,2158,1039,1737,650,1772,403,328,445,200,2085,831,1364,1043,1570,405,148,620,834,1625,1368,223,596,1830,2230,390,2383,410,1001,1579,1533,96,60,690,767,278,128,393,1183,841,626,728,571
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2,448
Proteasomal protein catabolic process
54
123
2.316017
0.020557
Q9UL46,Q9UJX4,Q96KB5,Q9Y4X5,Q14139,Q92530,P04062,O94874,P60900,P61086,P30260,P62191,Q04323,Q9UJX2,Q96A33,P49721,P25786,Q9BUN8,Q9NXV2,P28072,Q16763,P25789,P46379,Q6ZXV5,Q13617,Q9NRR5,P48506,P17612,Q5TDH0,Q9GZP4,Q99460,Q8TCT9,Q06787,P63208,P08238,P28074,P61289,Q99436,Q5VYK3,Q92990,P51665,Q9Y5K6,P28070,P25787,Q9UJX3,O75150,O14818,Q14258,O15372,P20618,Q9ULT8,Q15008,P54727,Q9UNN5
Processes and pathways
GO Biological process
msigdb_gobp
128,278,533,415,678,148,265,396,152,402,26,526,155,690,427,38,667,169,170,48,445,549,55,180,714,320,187,435,591,722,596,68,713,587,704,87,708,223,617,620,341,627,98,354,767,494,604,508,490,239,393,650,247,656
1674,604,2014,2118,1588,1012,490,930,494,973,2197,396,1195,265,704,1063,1680,435,979,239,667,354,1109,549,1110,1250,1022,98,48,87,26,1553,1511,1434,821,55,187,1201,1390,1392,38,2079,1073,341,1768,1995,247,1074,1731,2313,1028,152,402,708,526,1436,1437,991,587,1350,155,750,713,828,2057,1264,714,993,1560,678,508,650,1359,1772,1612,1123,445,2085,591,617,180,1043,1490,1228,68,148,1087,2210,620,1493,834,427,1455,1575,1368,533,223,596,2334,169,722,1533,1407,320,170,1794,2435,2193,962,690,767,278,128,393,2093,1183,656,1375,415,1141,1237,627,2075
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2,448
Membrane organization
41
164
2.147326
0.031767
Q9NS69,O15498,Q9UQB8,Q06481,O75844,Q9BVK6,P08183,Q9NPA0,P0DP25,O60343,Q96A33,Q8N1F7,Q14203,Q9NR31,Q86XL3,P45880,O00429,Q13505,Q8IWA4,P46379,P50570,P48506,Q92599,Q15392,Q8NFQ8,Q9Y2U8,O75340,Q15436,Q9NQC3,P61586,P50897,O43681,P48739,Q9NX63,Q00169,O14737,P41440,P49354,Q5JRA6,Q9H3K2,Q9NZZ3
Processes and pathways
GO Biological process
msigdb_gobp
2,254,10,137,12,146,20,158,280,395,427,426,295,428,39,41,418,441,174,55,439,187,189,64,194,196,197,328,202,79,211,209,340,358,365,229,240,113,368,253,263
2096,844,418,1290,1463,229,1190,1331,1802,731,1711,254,2390,699,209,930,1378,395,1100,931,197,886,1846,1381,1416,1712,12,1715,1592,1716,887,1760,1806,544,455,1146,888,1637,1419,1718,1505,576,636,20,1941,1644,280,1150,434,1018,1855,2200,1386,1723,1895,891,857,892,2345,240,2018,41,2385,55,1470,187,340,113,673,2079,1344,439,211,1766,744,1651,674,1768,1730,675,1258,505,1204,2019,79,1206,2314,1953,1520,365,1075,1478,137,1077,589,648,1610,441,993,295,1356,869,1265,1868,796,64,328,1267,1361,1447,1268,368,717,2062,1043,39,875,174,1873,2189,426,1699,1273,2357,194,912,913,1178,189,512,427,1625,2211,1576,2295,1531,146,2393,253,922,158,202,1182,428,2,1881,358,263,1535,924,1458,964,599,1838,1138,1325,966,1184,1375,10,196,1842,692,2074
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2,448
Cholesterol biosynthesis
6
13
2.114168
0.034501
Q15392,Q16850,P48449,Q14739,Q9BWD1,P37268
Processes and pathways
Reactome Pathways
msigdb_reactome
64,33,42,82,58,59
1335,59,42,1687,644,2020,1354,82,64,1823,33,58,112
-0.13821085131774094,2.5591211541242838,2.870946367764477,-0.3988970237964776,0.3665164111684586,-0.6767499381038484,-0.13821085131774094,1.9682464398947368,2.3674519132998197,-0.5009758947381806,3.334144431170288,2.5746279724078236,1.661989469315608
2,448
Vacuole
28
166
2.079411
0.03758
P19474,Q15165,Q9UHG3,Q9UMR5,Q8WTV0,P38435,P21281,Q5BJF2,Q8N511,Q8NCC3,P42785,Q9H7Z7,Q9UM22,Q8IV08,P42892,P07602,Q99523,P10619,P20645,P50897,O43681,Q969Q5,Q9UIQ6,Q8NHP8,Q99536,P41440,Q14108,Q9NZZ3
Localization
GO Cellular component
msigdb_gocc
130,8,9,139,16,269,266,24,31,32,35,45,50,182,56,185,190,67,72,211,209,88,96,100,103,240,118,263
1708,2096,844,1843,1886,1463,1142,1711,926,699,209,929,493,336,734,1143,1849,1715,1294,455,2145,2304,265,2324,889,1016,1244,1505,433,1017,185,2306,576,636,1679,307,704,1941,1149,2275,422,67,1547,1150,1103,1645,1197,1248,1549,1809,130,72,266,816,817,1388,1110,1599,398,982,608,269,2446,1389,1684,240,1252,35,56,821,1470,1072,1306,211,1254,460,1255,1766,744,2425,1651,987,1994,523,1731,1028,1204,989,1205,709,2314,1261,710,897,1351,1690,1954,384,1479,327,2055,898,589,2023,1611,590,649,118,1400,8,24,1362,1917,182,1127,31,1491,32,757,100,16,1621,595,1276,1044,88,446,1455,1625,1277,2211,621,596,484,190,103,1830,1529,1576,1750,1048,515,1181,410,763,45,2034,320,375,263,1535,840,924,9,689,96,50,1839,139,1325,1184,1186,1056,1189,2075,769
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2,448
Tetrapyrrole binding
6
12
2.058419
0.03955
Q16850,O43169,O15173,Q9H7Z7,P30519,Q8WUJ1
Functions
GO Molecular function
msigdb_gomf
33,34,73,45,22,127
417,73,34,637,129,1597,22,33,127,514,344,45
0.6102461852178491,2.1298086208718625,3.271800569805815,0.3665164111684586,1.4568099464483921,-0.3321900474773907,3.617828009062447,3.334144431170288,1.4778430925011763,0.5037535854216291,0.739459437121635,2.8424434207788134
2,448
Mitotic metaphase and anaphase
27
116
2.039126
0.041437
Q9UL46,Q9UJX4,Q92530,O43242,P60900,P30260,Q2NKX8,Q8N1F7,P49721,Q86XL3,P28072,Q8NFH4,Q15691,Q9Y266,Q9Y2U8,Q14739,P28074,P42166,Q99436,P51665,Q13409,P25787,P28070,P06493,Q9BTX1,P20618,Q9BUF5
Processes and pathways
Reactome Pathways
msigdb_reactome
128,278,148,264,152,26,425,426,38,39,48,317,179,321,196,82,87,339,223,341,356,354,98,352,108,239,390
1800,451,845,1674,604,1588,926,264,927,699,573,1415,1377,543,1416,1712,973,1146,352,780,979,1855,239,1386,667,354,1109,549,1022,98,48,87,670,1154,26,1511,339,1685,1434,1949,1201,1392,38,1992,1344,341,1516,1768,1074,988,152,708,526,1436,1437,612,1031,2263,710,750,899,828,356,2155,1481,1400,2000,1039,82,1121,1963,650,179,445,1360,425,1563,532,719,800,39,2333,426,1524,317,1663,1570,1571,148,1366,513,1277,2211,223,596,2230,2295,108,390,2383,2231,2069,1533,2362,2037,961,690,767,278,128,1325,841,1587,321,196,571
-0.5009758947381806,0.5573562198457855,0.1954125848637109,-0.3988970237964776,0.39434193438019527,-0.3321900474773907,0.13673713573536073,0.8891085200681355,0.13673713573536073,0.31028208638028104,0.4219761463810362,-0.20187454584837183,-0.16992097114184565,0.44942133352143965,-0.20187454584837183,-0.4326504272995773,0.10708006863031112,-0.013741371797105306,0.7139531433521713,0.2532540711162199,0.10708006863031112,-0.535555719910308,0.9618336856730934,-0.16992097114184565,0.33849725070930553,0.7139531433521713,0.016798620797514572,0.44942133352143965,0.07720648685986563,1.7798568211263002,2.784711107983899,1.9127456977587534,0.33849725070930553,-0.013741371797105306,3.467255223026549,-0.2665252615044035,0.739459437121635,-0.3988970237964776,-0.20187454584837183,-0.6055695540857844,-0.04450929815907613,-0.16992097114184565,3.1171859178587953,-0.6410118115887157,-0.13821085131774094,0.739459437121635,-0.2665252615044035,-0.4666754370813207,0.047113613573717794,0.10708006863031112,1.3061897616761267,0.31028208638028104,0.4766797433412753,-0.20187454584837183,-0.20187454584837183,0.39434193438019527,0.07720648685986563,-1.0514067221556325,0.31028208638028104,0.28186851004785385,0.1661804150958811,0.2244362755490974,0.7139531433521713,-0.8600338466358575,-0.23407485992918883,-0.16992097114184565,-0.6410118115887157,0.07720648685986563,1.9682464398947368,0.016798620797514572,-0.6055695540857844,0.3665164111684586,1.1721404501200772,0.5838892489081151,-0.13821085131774094,0.6102461852178491,-0.29922916393356874,0.4766797433412753,0.31028208638028104,0.2532540711162199,3.1171859178587953,-1.2107600767809958,0.6102461852178491,-0.2665252615044035,0.7899807036477229,-0.3654114610118159,-0.29922916393356874,-0.29922916393356874,1.3280784620023343,-0.13821085131774094,0.5037535854216291,-0.07550814716240413,-0.9355777762145688,1.0332193663097253,0.4219761463810362,-0.9738472000599042,-1.1303628354172428,1.7016989070273105,0.6624398734283633,-1.5477257042197843,-0.9738472000599042,-0.7127882759896713,-0.2665252615044035,-1.4183692792800806,-0.6767499381038484,0.13673713573536073,0.33849725070930553,0.28186851004785385,0.8891085200681355,1.4778430925011763,-0.10674096394992204,0.2244362755490974,-0.29922916393356874,0.7899807036477229,1.1263898453171806,0.44942133352143965
2,448
Transporters
72
274
2.035603
0.04179
Q8TAG9,P54105,O00400,O96008,P55060,O60684,Q9HD20,O75844,P24390,Q9BXS5,Q8WTV0,O43772,P21281,P08183,Q9UBX3,Q8IXU6,Q5BJF2,Q99808,Q9NPA0,Q5T1Q4,Q96H78,Q8N511,P49257,O60343,Q96A33,Q8N1F7,Q99720,P80723,O95563,P45880,Q9BUN8,Q9H2D1,O00429,Q8TB61,Q8IWA4,Q9H814,Q8NFH4,Q6ZXV5,Q9NRR5,P07602,P50570,P63104,Q99523,P12235,Q9UIA9,O15127,Q9UM00,Q969V3,P50995,O75340,P20645,Q07065,P35613,O76094,Q9Y320,Q9NR77,Q6N075,O43808,O43681,P05067,O96005,Q70HW3,P06493,O60637,Q15904,Q6UW68,Q9BTX1,P41440,Q5JRA6,P53985,Q14108,Q96N66
Functions
Protein Atlas Protein class
protein_atlas_protein_class
131,258,6,255,382,379,138,12,13,410,16,17,266,20,149,23,24,154,158,29,30,31,159,395,427,426,36,423,291,41,169,43,418,175,174,449,317,180,320,185,439,440,190,434,195,431,332,464,460,197,72,327,74,325,467,81,214,210,209,220,97,99,352,104,233,106,108,240,368,114,118,124
2144,1462,2096,1239,6,694,695,418,1539,1328,1010,2301,1190,771,1413,1588,542,431,731,628,2390,773,209,929,17,210,1378,395,1100,104,379,1845,1675,197,1101,1143,1712,848,12,1293,1715,325,1195,1294,1716,887,1806,496,1241,291,2145,97,255,634,2236,497,849,888,662,1637,1243,889,663,1419,220,1718,1640,352,1505,185,636,20,1679,704,1506,1149,1247,1854,1064,1645,472,434,1548,1594,1595,1197,780,890,1018,2147,981,72,1722,266,816,2100,1019,13,1469,2310,608,1068,74,1856,1200,1389,1948,1684,240,41,1949,1470,984,159,2123,673,1726,1992,439,460,1766,1073,2425,707,1727,1516,1993,1994,114,258,1517,1257,382,1731,1258,988,2313,505,1347,611,709,1206,2181,2314,612,1261,440,862,1350,2239,423,825,1477,1351,1954,712,1262,327,1609,1077,1653,898,899,1441,1906,118,948,1120,1121,869,2265,1613,233,871,1267,24,1268,368,532,29,214,1042,2242,106,180,99,719,174,23,1127,2209,426,31,1273,996,317,1663,131,1228,175,1825,1744,481,16,1571,594,1366,1087,513,1044,464,427,1526,1625,1277,30,1090,124,1828,803,621,1783,190,1133,36,2111,154,1180,108,169,2361,2231,2069,410,2393,43,2297,685,449,958,1137,1232,922,138,158,623,81,1791,320,1671,724,1535,1672,962,149,1052,1324,963,689,2424,195,965,1884,1537,332,2349,467,1098,1461,692,627,1099,468,1058
-0.8600338466358575,-0.23407485992918883,-0.7857834156318783,-0.07550814716240413,4.17639495057996,0.31028208638028104,0.31028208638028104,0.6102461852178491,-0.29922916393356874,-0.13821085131774094,0.07720648685986563,-1.1703784526483574,-0.04450929815907613,0.2532540711162199,-0.20187454584837183,-0.3321900474773907,0.44942133352143965,0.5838892489081151,0.28186851004785385,0.3665164111684586,-1.6360731710669292,0.2532540711162199,1.0567243347808781,0.13673713573536073,3.6850112480094657,1.0567243347808781,-0.16992097114184565,0.6364290605632036,0.016798620797514572,1.7409854217614293,0.6624398734283633,-0.535555719910308,-0.3988970237964776,1.103308081617117,0.016798620797514572,-0.013741371797105306,-0.4326504272995773,0.1954125848637109,3.815266225617852,-0.10674096394992204,-0.4326504272995773,0.7648013431550654,-0.04450929815907613,-0.10674096394992204,-0.4326504272995773,0.1661804150958811,-0.5009758947381806,0.5037535854216291,-0.07550814716240413,0.8398590107348664,-0.8600338466358575,1.7991392364065326,0.9135017799843423,0.3665164111684586,-1.0124550937073367,0.5037535854216291,0.1954125848637109,0.1661804150958811,0.33849725070930553,-0.3654114610118159,-0.07550814716240413,0.1661804150958811,0.33849725070930553,-0.20187454584837183,1.0332193663097253,-0.4326504272995773,-0.3654114610118159,0.7139531433521713,-0.2665252615044035,1.1493334889520355,0.3665164111684586,3.629123698076312,-0.3988970237964776,0.31028208638028104,-0.2665252615044035,-0.013741371797105306,-0.07550814716240413,-0.535555719910308,0.047113613573717794,-0.3654114610118159,0.5306450322137474,0.5838892489081151,-0.29922916393356874,-0.3321900474773907,-0.3321900474773907,-0.04450929815907613,0.2532540711162199,0.1661804150958811,0.07720648685986563,-0.8600338466358575,0.10708006863031112,2.182086183200635,-0.4326504272995773,0.8891085200681355,0.2244362755490974,-0.7857834156318783,0.07720648685986563,3.8046139928930724,-0.23407485992918883,-1.1703784526483574,0.39434193438019527,0.047113613573717794,2.1298086208718625,-0.535555719910308,-0.04450929815907613,-0.16992097114184565,-0.6055695540857844,-0.3988970237964776,0.9618336856730934,2.9411724327983952,-0.6055695540857844,-0.23407485992918883,0.10708006863031112,1.2620294862248376,-0.8227493700904442,0.33849725070930553,-0.4326504272995773,-0.6410118115887157,0.5838892489081151,0.5573562198457855,-0.4666754370813207,0.047113613573717794,-2.2560739912554033,0.31028208638028104,-0.4326504272995773,-0.2665252615044035,-0.6410118115887157,-0.6410118115887157,1.6218490896718054,0.9135017799843423,-0.2665252615044035,-0.07550814716240413,0.6624398734283633,-0.4326504272995773,-0.07550814716240413,0.10708006863031112,-1.1703784526483574,0.5037535854216291,-0.13821085131774094,0.39434193438019527,0.31028208638028104,-0.04450929815907613,-0.8976416715543978,-1.1703784526483574,0.39434193438019527,-0.07550814716240413,0.5838892489081151,0.1954125848637109,-0.13821085131774094,-1.0124550937073367,0.6102461852178491,0.2244362755490974,-0.23407485992918883,-0.13821085131774094,-0.6055695540857844,0.31028208638028104,-0.07550814716240413,0.7648013431550654,-0.3321900474773907,0.047113613573717794,-0.3654114610118159,0.1661804150958811,0.1661804150958811,-0.20187454584837183,-0.570418912354578,1.5402423267363425,0.13673713573536073,0.016798620797514572,0.016798620797514572,0.1954125848637109,-1.0514067221556325,-0.3321900474773907,0.9857756041121978,0.1954125848637109,-0.07550814716240413,3.5143383858043737,-0.07550814716240413,0.6882805896994563,0.4766797433412753,3.3953239924028624,1.0567243347808781,0.07720648685986563,-1.0124550937073367,1.7016989070273105,1.1721404501200772,1.7798568211263002,0.31028208638028104,1.1948121451525973,3.526002825244512,0.016798620797514572,-0.9355777762145688,0.6102461852178491,3.3464722631890886,-0.07550814716240413,0.10708006863031112,0.7899807036477229,-0.3654114610118159,1.4568099464483921,-0.04450929815907613,1.1948121451525973,-0.5009758947381806,-0.4326504272995773,0.5306450322137474,3.7180796333138844,-0.29922916393356874,0.4219761463810362,-0.13821085131774094,0.047113613573717794,0.5037535854216291,0.07720648685986563,0.5573562198457855,0.6102461852178491,-0.2665252615044035,-0.3321900474773907,-0.07550814716240413,3.3953239924028624,0.047113613573717794,1.4987587796791746,-0.5009758947381806,0.2532540711162199,0.39434193438019527,-0.4666754370813207,1.1493334889520355,0.016798620797514572,3.2338191303883956,-0.7857834156318783,1.3061897616761267,-0.013741371797105306,1.7016989070273105,1.21734996952083,-1.4183692792800806,-0.9738472000599042,-0.7127882759896713,0.6364290605632036,-1.6360731710669292,2.870946367764477,-1.1303628354172428,0.33849725070930553,0.5838892489081151,0.13673713573536073,0.016798620797514572,-0.04450929815907613,0.1661804150958811,1.4143866320634981,1.284173868734211,0.39434193438019527,1.986559419744753,-0.4666754370813207,0.7899807036477229,-0.3654114610118159,0.31028208638028104,-0.2665252615044035,-0.3654114610118159,0.13673713573536073,1.3280784620023343,0.07720648685986563,-0.10674096394992204,0.13673713573536073,0.33849725070930553,-2.2053216053636544,1.1263898453171806,0.13673713573536073,-0.535555719910308,-0.2665252615044035,0.7648013431550654,-1.2926450388735131,0.5573562198457855,0.047113613573717794,-0.20187454584837183,0.33849725070930553,0.39434193438019527,0.047113613573717794,0.5573562198457855,0.07720648685986563
2,448
Lipid binding
19
104
2.031528
0.042202
Q06481,Q99584,Q8WTV0,P38435,Q9BQE5,P04062,A6NIH7,P21796,Q8NCC3,P30086,P45880,Q9UM22,P07602,O15173,Q9Y5X3,P50897,P02656,P28070,Q14108
Functions
GO Molecular function
msigdb_gomf
137,142,16,269,18,265,25,28,32,162,41,50,185,73,216,211,226,98,118
2144,25,417,418,1142,73,1012,699,1541,1378,1100,336,734,1195,1294,226,265,888,663,1505,185,1147,636,577,2344,1150,1064,976,472,1942,1151,28,1723,1550,667,98,475,162,2122,1068,269,41,1513,340,211,460,1686,1729,789,1731,270,505,2314,2263,365,1608,1478,1954,137,1077,2022,2128,1610,385,649,118,1120,2058,2265,614,1265,1362,872,32,1663,16,1178,1924,1625,2089,2005,142,1831,1750,1927,759,18,1180,1095,1930,2393,1579,623,924,1796,1053,50,966,768,1375,570,1140,2074,216
-0.8600338466358575,3.4908824258174365,0.6102461852178491,0.6102461852178491,-0.013741371797105306,2.1298086208718625,0.07720648685986563,0.31028208638028104,-0.29922916393356874,-0.16992097114184565,0.016798620797514572,0.739459437121635,0.28186851004785385,-0.04450929815907613,-0.10674096394992204,1.009570306217981,0.8891085200681355,0.1661804150958811,0.33849725070930553,-0.2665252615044035,1.1493334889520355,-0.013741371797105306,0.3665164111684586,0.4219761463810362,-1.2926450388735131,-0.013741371797105306,0.047113613573717794,0.10708006863031112,0.5306450322137474,-0.6055695540857844,-0.013741371797105306,3.3953239924028624,-0.4326504272995773,-0.29922916393356874,0.33849725070930553,1.7798568211263002,0.5306450322137474,1.2397552982334583,-0.8227493700904442,0.047113613573717794,0.8891085200681355,2.9411724327983952,-0.2665252615044035,0.739459437121635,1.0567243347808781,0.5573562198457855,-0.3988970237964776,-0.4326504272995773,0.2532540711162199,-0.4326504272995773,0.8891085200681355,0.5037535854216291,-1.1703784526483574,-1.0514067221556325,0.6882805896994563,-0.3321900474773907,-0.23407485992918883,-0.6055695540857844,1.4143866320634981,0.047113613573717794,-0.6767499381038484,-0.8227493700904442,-0.3321900474773907,0.6624398734283633,0.3665164111684586,1.5402423267363425,0.016798620797514572,-0.7127882759896713,-1.0514067221556325,0.39434193438019527,-0.07550814716240413,-0.13821085131774094,0.1954125848637109,3.3464722631890886,-0.3654114610118159,3.7180796333138844,-0.013741371797105306,-0.570418912354578,-0.3321900474773907,-0.7491312591646139,-0.6410118115887157,1.3929940997311916,-0.5009758947381806,-0.4326504272995773,-0.570418912354578,0.28186851004785385,3.6739117234855883,-0.013741371797105306,0.047113613573717794,-0.570418912354578,-1.6360731710669292,-0.29922916393356874,0.39434193438019527,0.1661804150958811,-0.4666754370813207,0.07720648685986563,2.7554745032452117,0.13673713573536073,0.28186851004785385,-0.13821085131774094,0.44942133352143965,0.016798620797514572,-0.7127882759896713,1.0567243347808781
2,448
Ectrodactyly
6
12
1.977736
0.047959
Q99720,Q13363,P48449,Q9UBM7,Q9NR77,Q6DKJ4
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
36,133,42,112,81,188
887,219,812,42,1604,1955,133,188,36,837,81,112
0.1661804150958811,1.0332193663097253,0.2244362755490974,2.870946367764477,-0.3321900474773907,-0.6055695540857844,1.4356581841942115,1.1493334889520355,3.2338191303883956,0.2244362755490974,1.986559419744753,1.661989469315608
2,448
Protein targeting to mitochondrion
10
32
2.668442
0.00762
Q9NS69,O00170,O14737,P55786,O60830,O95831,Q99595,O96008,Q9UII2,Q8N4H5
Processes and pathways
GO Biological process
msigdb_gobp
3,131,4,67,11,233,54,212,159,95
131,4,259,11,1965,1138,233,212,512,1720,1968,1318,765,1494,67,422,568,363,1237,1039,1238,487,882,95,54,1346,466,888,3,889,159,667
1.3362880774876855,5.020520990853268,0.9245131151656795,4.069391431706361,-0.6176915568126867,-0.018876472558511177,0.9766048134496434,1.0285153268615765,0.5009909364490867,-0.41503650551512866,-0.6176915568126867,-0.13087043860862127,0.257153623658796,-0.24380646037004453,2.0073104645183664,0.6346723461909124,0.4471669100474672,0.7407340833564946,-0.0747573422143828,0.06451636689744125,-0.0747573422143828,0.5546128696330814,0.17492319576901172,1.6380330471064772,2.272884776106456,-0.13087043860862127,0.5813488413779345,0.17492319576901172,5.810280867281288,0.17492319576901172,1.2343868372163067,0.3660462944977283
2,448
Nucleophile aminohydrolases, N-terminal [IPR029055]
6
19
2.645874
0.008148
Q9UJ14,P28070,P28072,P49721,Q99436,P20618
Sequence
InterPro Superfamily
interpro_homologous_superfamily
1,8,75,50,185,57
898,1599,57,355,562,1143,440,1062,8,75,324,615,50,215,1643,2373,2071,185,1
0.14740431916148347,-0.3291429555446635,2.2249146983537895,0.7407340833564946,0.4471669100474672,-0.018876472558511177,0.608035231255206,0.03677536139040555,4.4128589064029,1.885156869690082,0.7934770501751663,0.3931382140667069,2.320717274616999,1.0285153268615765,-0.35771164197715183,-1.4316999561995352,-0.7055340989840095,1.1318011406501396,8.327942701909974
2,448
Calcium-binding protein
10
16
2.523015
0.011635
Q02818,P27797,P43307,Q15293,Q99584,O43852,Q9Y376,P80303,Q14257,P0DP25
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
36,134,72,302,49,172,414,22,124,61
172,61,134,1144,72,1413,419,22,36,124,302,1338,1738,49,2284,414
1.1575125786951872,2.128556440120726,1.3362880774876855,-0.018876472558511177,1.9096612967942113,-0.18721902917717162,0.6346723461909124,3.250355654680291,2.6985777517226017,1.3869867592075118,0.8460311580867192,-0.13087043860862127,-0.41503650551512866,2.344582343111722,-1.0934762379971246,0.6612604898918479
2,448
Negative regulation of mrna catabolic process
13
23
2.475424
0.013308
P35637,Q14011,Q14103,Q06787,Q13148,Q99729,P98175,P67809,Q9Y2W1,P07910,O60506,Q92804,P16989
Processes and pathways
GO Biological process
msigdb_gobp
32,33,392,448,330,108,140,77,350,296,293,31,30
293,476,296,532,30,32,77,140,1829,448,1973,330,1035,33,392,1236,2427,1337,1702,31,108,1049,350
0.8460311580867192,0.5546128696330814,0.8460311580867192,0.4741043446214123,2.838155755900563,2.768507128882199,1.885156869690082,1.310876101103491,-0.5014994916724022,0.608035231255206,-0.6176915568126867,0.7934770501751663,0.06451636689744125,2.768507128882199,0.6877999628930653,-0.0747573422143828,-2.273305646512073,-0.13087043860862127,-0.3863426724775272,2.838155755900563,1.5380969287016093,0.06451636689744125,0.7671293164449878
2,448
Receptor
13
30
2.448124
0.01436
O15173,Q9NS69,Q8WTV0,Q5KU26,Q99523,P20645,P24390,P11717,Q9Y2W1,P35613,P08865,O00264,P02786
Functions
Protein Atlas Molecular function
protein_atlas_molecular_function
66,3,73,142,177,299,15,297,350,184,340,310,62
310,371,66,62,1677,977,1678,340,796,1942,297,1858,299,15,184,1732,2163,1116,1198,142,73,1045,177,849,2422,3,1051,350,929,1009
0.8197775699048265,0.7142910626044647,2.0073104645183664,2.080165521066943,-0.3863426724775272,0.09220127675854774,-0.3863426724775272,0.7671293164449878,0.22979748844929848,-0.5885447711477003,0.8460311580867192,-0.5304492364547555,0.8460311580867192,3.6311676328017297,1.1318011406501396,-0.41503650551512866,-0.8236155713970702,0.008977877355335437,-0.04678808024453321,1.2854220588775127,1.9096612967942113,0.06451636689744125,1.1575125786951872,0.20238746499953386,-2.007441484636362,5.810280867281288,0.06451636689744125,0.7671293164449878,0.14740431916148347,0.09220127675854774
2,448
Proteasome core complex
8
15
2.444836
0.014492
P28070,P28074,P28072,P25786,P49721,Q99436,P60900,P20618
Localization
GO Cellular component
msigdb_gocc
8,324,75,355,50,185,215,57
898,57,355,562,1143,440,1062,8,75,324,615,50,215,1468,185
0.14740431916148347,2.2249146983537895,0.7407340833564946,0.4471669100474672,-0.018876472558511177,0.608035231255206,0.03677536139040555,4.4128589064029,1.885156869690082,0.7934770501751663,0.3931382140667069,2.320717274616999,1.0285153268615765,-0.21548267738224194,1.1318011406501396
2,448
Calmodulin
6
12
2.433616
0.014949
Q02818,Q99584,O43852,P80303,Q14257,P0DP25
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
36,49,172,22,124,61
172,61,1144,1413,419,22,36,124,302,1338,1738,49
1.1575125786951872,2.128556440120726,-0.018876472558511177,-0.18721902917717162,0.6346723461909124,3.250355654680291,2.6985777517226017,1.3869867592075118,0.8460311580867192,-0.13087043860862127,-0.41503650551512866,2.344582343111722
2,448
Intracellular calcium-sensing protein
6
12
2.433616
0.014949
Q02818,Q99584,O43852,P80303,Q14257,P0DP25
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
36,49,172,22,124,61
172,61,1144,1413,419,22,36,124,302,1338,1738,49
1.1575125786951872,2.128556440120726,-0.018876472558511177,-0.18721902917717162,0.6346723461909124,3.250355654680291,2.6985777517226017,1.3869867592075118,0.8460311580867192,-0.13087043860862127,-0.41503650551512866,2.344582343111722
2,448
Proteasome, subunit alpha/beta [IPR001353]
8
14
2.416337
0.015678
P28070,P28074,P28072,P25786,P49721,Q99436,P60900,P20618
Sequence
InterPro Family
interpro_family
8,324,75,355,50,185,215,57
898,57,355,562,1143,440,1062,8,75,324,615,50,215,185
0.14740431916148347,2.2249146983537895,0.7407340833564946,0.4471669100474672,-0.018876472558511177,0.608035231255206,0.03677536139040555,4.4128589064029,1.885156869690082,0.7934770501751663,0.3931382140667069,2.320717274616999,1.0285153268615765,1.1318011406501396
2,448
Negative regulation of rna splicing
12
17
2.407682
0.016054
Q13242,P61978,Q16629,O75494,P98175,Q8WXF0,Q9UKA9,O00422,P38159,Q08170,P26368,P22626
Processes and pathways
GO Biological process
msigdb_gobp
483,97,364,282,140,176,471,292,76,541,496,155
292,282,155,496,1487,76,97,1231,140,1538,541,1974,483,542,364,176,471
0.8460311580867192,0.8722380943101374,1.2343868372163067,0.5278270058270058,-0.24380646037004453,1.885156869690082,1.6131083535339024,-0.0747573422143828,1.310876101103491,-0.2721908092399754,0.4741043446214123,-0.6176915568126867,0.5546128696330814,0.4741043446214123,0.7407340833564946,1.1575125786951872,0.5813488413779345
2,448
Rna stabilization
12
25
2.309147
0.020935
P35637,Q14011,Q13148,P98175,Q08J23,P67809,Q9H814,Q9Y2W1,P07910,O60506,Q92804,P16989
Processes and pathways
GO Biological process
msigdb_gobp
32,33,330,140,167,77,144,350,296,293,31,30
293,1630,476,296,532,30,32,77,140,1829,1973,167,330,1035,33,392,1236,2427,1337,1702,31,2273,144,1049,350
0.8460311580867192,-0.35771164197715183,0.5546128696330814,0.8460311580867192,0.4741043446214123,2.838155755900563,2.768507128882199,1.885156869690082,1.310876101103491,-0.5014994916724022,-0.6176915568126867,1.183180510648192,0.7934770501751663,0.06451636689744125,2.768507128882199,0.6877999628930653,-0.0747573422143828,-2.273305646512073,-0.13087043860862127,-0.3863426724775272,2.838155755900563,-1.0631967014757355,1.2854220588775127,0.06451636689744125,0.7671293164449878
2,448
Receptor
7
18
2.300984
0.021393
Q9NR77,Q9BUN8,Q8WTV0,P20645,Q567V2,Q9UQB8,A6NIH7
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
35,169,73,299,19,153,25
25,1476,1752,1016,2024,1677,297,299,2163,19,73,1204,169,1850,435,35,1927,153
3.1140163857198093,-0.24380646037004453,-0.443793605326457,0.06451636689744125,-0.6761857030466238,-0.3863426724775272,0.8460311580867192,0.8460311580867192,-0.8236155713970702,3.475322647910461,1.9096612967942113,-0.04678808024453321,1.183180510648192,-0.5014994916724022,0.6346723461909124,2.721918973194284,-0.5594641647245177,1.259925716446449
2,448
Positive regulation of rna splicing
9
21
2.268354
0.023308
Q14011,P30041,P19338,P38159,P62995,Q9Y2W1,Q13243,P98179,Q96EP5
Processes and pathways
GO Biological process
msigdb_gobp
33,325,322,76,206,350,271,90,454
692,1223,831,322,1861,496,325,76,1368,206,90,1611,271,705,621,33,1038,454,1512,1810,350
0.3117056396225893,-0.0747573422143828,0.20238746499953386,0.7934770501751663,-0.5304492364547555,0.5278270058270058,0.7934770501751663,1.885156869690082,-0.1590150898512352,1.0544032957346032,1.6877650123528685,-0.3291429555446635,0.8983986553417496,0.3117056396225893,0.3931382140667069,2.768507128882199,0.06451636689744125,0.608035231255206,-0.24380646037004453,-0.47261444201815506,0.7671293164449878
2,448
Negative regulation of mrna processing
11
20
2.252342
0.024301
O75494,Q13242,P61978,Q16629,P98175,Q8WXF0,O00422,P38159,Q08170,P26368,P22626
Processes and pathways
GO Biological process
msigdb_gobp
282,483,97,364,140,176,292,76,541,496,155
669,292,825,282,155,496,1487,76,97,140,1538,541,1974,483,542,364,814,1696,1420,176
0.33890221574820123,0.8460311580867192,0.20238746499953386,0.8722380943101374,1.2343868372163067,0.5278270058270058,-0.24380646037004453,1.885156869690082,1.6131083535339024,1.310876101103491,-0.2721908092399754,0.4741043446214123,-0.6176915568126867,0.5546128696330814,0.4741043446214123,0.7407340833564946,0.22979748844929848,-0.3863426724775272,-0.18721902917717162,1.1575125786951872
2,448
Gene and protein expression by jak stat signaling after interleukin 12 stimulation
8
24
2.233532
0.025514
P26038,O00170,Q99439,P78417,O14979,Q13126,P14174,P22626
Processes and pathways
Reactome Pathways
msigdb_reactome
342,131,276,359,113,149,89,155
131,113,942,1442,1222,732,979,89,800,375,155,1564,342,1227,2062,534,834,1189,359,567,149,1112,276,891
1.3362880774876855,1.4627250220353432,0.11983046945965561,-0.21548267738224194,-0.0747573422143828,0.2844562241767139,0.09220127675854774,1.6877650123528685,0.22979748844929848,0.7142910626044647,1.2343868372163067,-0.30063616037720137,0.7671293164449878,-0.0747573422143828,-0.7055340989840095,0.4741043446214123,0.20238746499953386,-0.04678808024453321,0.7407340833564946,0.4471669100474672,1.259925716446449,0.008977877355335437,0.8983986553417496,0.17492319576901172
2,448
Rhobtb1 gtpase cycle
11
19
2.230479
0.025716
Q7Z6E9,Q99832,P78371,P38159,P62995,O43396,Q13464,P07910,Q9BT78,Q8N684,P08670
Processes and pathways
Reactome Pathways
msigdb_reactome
191,598,537,76,206,507,543,296,52,347,63
507,296,63,76,617,206,537,743,543,1374,1335,814,191,1202,347,1583,598,52,1962
0.5009909364490867,0.8460311580867192,2.080165521066943,1.885156869690082,0.3931382140667069,1.0544032957346032,0.4741043446214123,0.2844562241767139,0.4741043446214123,-0.1590150898512352,-0.13087043860862127,0.22979748844929848,1.106045948303311,-0.04678808024453321,0.7671293164449878,-0.30063616037720137,0.4201783089598065,2.296818140139889,-0.5885447711477003
2,448
Negative regulation of mrna splicing via spliceosome
11
15
2.215573
0.026721
Q13242,P61978,Q16629,O75494,P98175,Q8WXF0,O00422,P38159,Q08170,P26368,P22626
Processes and pathways
GO Biological process
msigdb_gobp
483,97,364,282,140,176,292,76,541,496,155
292,282,155,496,1487,76,97,140,1538,541,1974,483,542,364,176
0.8460311580867192,0.8722380943101374,1.2343868372163067,0.5278270058270058,-0.24380646037004453,1.885156869690082,1.6131083535339024,1.310876101103491,-0.2721908092399754,0.4741043446214123,-0.6176915568126867,0.5546128696330814,0.4741043446214123,0.7407340833564946,1.1575125786951872
2,448
Organic acid transmembrane transport
6
21
2.200798
0.02775
P08183,P53985,O43772,Q9UBX3,O95563,Q9H2D1
Processes and pathways
GO Biological process
msigdb_gobp
188,268,20,116,338,24
20,975,1561,338,1677,188,1998,1404,1445,1895,357,2300,268,1068,1198,1847,24,1211,1122,116,890
3.4305513740522002,0.09220127675854774,-0.30063616037720137,0.7671293164449878,-0.3863426724775272,1.106045948303311,-0.6469050293486138,-0.18721902917717162,-0.21548267738224194,-0.5594641647245177,0.7407340833564946,-1.1542633725241198,0.8983986553417496,0.03677536139040555,-0.04678808024453321,-0.5014994916724022,3.205024401857335,-0.04678808024453321,0.008977877355335437,1.4627250220353432,0.17492319576901172
2,448
Protein transmembrane transport
6
16
2.200783
0.027751
Q9NS69,O43615,O60830,O95831,Q99595,O96008
Processes and pathways
GO Biological process
msigdb_gobp
3,259,11,233,54,212
259,11,1138,233,212,1720,678,2329,1497,2239,363,1039,54,888,3,1299
0.9245131151656795,4.069391431706361,-0.018876472558511177,0.9766048134496434,1.0285153268615765,-0.41503650551512866,0.33890221574820123,-1.2153589024555271,-0.24380646037004453,-0.972806669224598,0.7407340833564946,0.06451636689744125,2.272884776106456,0.17492319576901172,5.810280867281288,-0.10278465967521874
2,448
Proteasome degradation
20
41
2.198605
0.027906
P28070,O75832,O00231,P61289,P49721,Q99436,P10321,P20618,P25787,P51665,P28074,P25789,P28072,P62191,P60900,Q99460,O43242,P25786,P01889,P49720
Processes and pathways
WikiPathways
msigdb_wp
8,265,280,420,50,185,559,57,562,442,324,440,75,590,215,629,474,355,494,615
280,1218,898,474,265,494,1104,1139,1018,559,1024,735,57,1364,355,562,1143,440,1062,8,75,324,1605,1186,1108,615,50,442,948,215,420,590,1032,1414,811,1277,1282,185,629,891,689
0.8722380943101374,-0.0747573422143828,0.14740431916148347,0.5546128696330814,0.8983986553417496,0.5278270058270058,0.008977877355335437,-0.018876472558511177,0.06451636689744125,0.4471669100474672,0.06451636689744125,0.2844562241767139,2.2249146983537895,-0.1590150898512352,0.7407340833564946,0.4471669100474672,-0.018876472558511177,0.608035231255206,0.03677536139040555,4.4128589064029,1.885156869690082,0.7934770501751663,-0.3291429555446635,-0.04678808024453321,0.008977877355335437,0.3931382140667069,2.320717274616999,0.608035231255206,0.11983046945965561,1.0285153268615765,0.6346723461909124,0.4201783089598065,0.06451636689744125,-0.18721902917717162,0.22979748844929848,-0.10278465967521874,-0.10278465967521874,1.1318011406501396,0.3931382140667069,0.17492319576901172,0.33890221574820123
2,448
Negative regulation of calcium ion transmembrane transport
6
7
2.163877
0.030474
P28161,Q06787,P21796,P62258,P78417,P0DP25
Processes and pathways
GO Biological process
msigdb_gobp
229,448,71,390,359,61
61,71,229,498,390,359,448
2.128556440120726,1.934128683586786,1.0025825863157696,0.5278270058270058,0.6877999628930653,0.7407340833564946,0.608035231255206
2,448
Frontotemporal dementia
6
9
2.156417
0.031051
P35637,Q13148,P09651,P05067,O96008,P22626
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
32,330,354,88,212,155
212,88,354,155,32,1370,330,1416,464
1.0285153268615765,1.6877650123528685,0.7407340833564946,1.2343868372163067,2.768507128882199,-0.1590150898512352,0.7934770501751663,-0.18721902917717162,0.5813488413779345
2,448
Amyloid beta binding
6
8
2.139272
0.032414
Q8WTV0,Q9UHV9,P61758,O15212,O00264,Q99471
Functions
GO Molecular function
msigdb_gomf
73,145,421,91,310,196
310,91,516,421,1195,73,196,145
0.8197775699048265,1.6629185313713613,0.5009909364490867,0.6346723461909124,-0.04678808024453321,1.9096612967942113,1.106045948303311,1.2854220588775127
2,448
Regulation of calcium ion transport
8
22
2.138676
0.032462
Q00535,P28161,Q06787,P62258,P21796,P78417,P61586,P0DP25
Processes and pathways
GO Biological process
msigdb_gobp
128,229,448,390,71,359,55,61
1360,583,61,832,865,1967,1226,1106,1363,71,1604,229,498,1682,1369,55,390,359,128,448,840,1645
-0.1590150898512352,0.4201783089598065,2.128556440120726,0.20238746499953386,0.17492319576901172,-0.6176915568126867,-0.0747573422143828,0.008977877355335437,-0.1590150898512352,1.934128683586786,-0.3291429555446635,1.0025825863157696,0.5278270058270058,-0.3863426724775272,-0.1590150898512352,2.2489170176016646,0.6877999628930653,0.7407340833564946,1.3616582201922978,0.608035231255206,0.20238746499953386,-0.35771164197715183
2,448
calmodulin-related
6
11
2.123799
0.033687
Q02818,Q99584,O43852,P80303,Q14257,P0DP25
Functions
Panther Protein class
panther_protein_class
36,49,172,22,124,61
172,61,498,1144,419,22,36,124,302,49,2284
1.1575125786951872,2.128556440120726,0.5278270058270058,-0.018876472558511177,0.6346723461909124,3.250355654680291,2.6985777517226017,1.3869867592075118,0.8460311580867192,2.344582343111722,-1.0934762379971246
2,448
Positive regulation of mrna splicing via spliceosome
7
16
2.115761
0.034365
Q14011,P30041,P19338,P38159,P62995,Q9Y2W1,P98179
Processes and pathways
GO Biological process
msigdb_gobp
33,325,322,76,206,350,90
1223,831,322,325,76,1368,206,90,1611,705,621,33,1038,454,1810,350
-0.0747573422143828,0.20238746499953386,0.7934770501751663,0.7934770501751663,1.885156869690082,-0.1590150898512352,1.0544032957346032,1.6877650123528685,-0.3291429555446635,0.3117056396225893,0.3931382140667069,2.768507128882199,0.06451636689744125,0.608035231255206,-0.47261444201815506,0.7671293164449878
2,448
Negative regulation of rna catabolic process
17
29
2.112961
0.034604
P35637,Q14011,Q14103,Q06787,Q13148,O75534,Q99729,P98175,Q08J23,P67809,Q9H814,Q9Y2W1,P07910,O60506,Q9GZT3,Q92804,P16989
Processes and pathways
GO Biological process
msigdb_gobp
32,33,392,448,330,476,108,140,167,77,144,350,296,293,549,31,30
293,1630,476,296,532,30,32,1529,77,140,1829,448,1973,167,330,1035,33,392,1236,2427,1337,1702,31,108,549,2273,144,1049,350
0.8460311580867192,-0.35771164197715183,0.5546128696330814,0.8460311580867192,0.4741043446214123,2.838155755900563,2.768507128882199,-0.2721908092399754,1.885156869690082,1.310876101103491,-0.5014994916724022,0.608035231255206,-0.6176915568126867,1.183180510648192,0.7934770501751663,0.06451636689744125,2.768507128882199,0.6877999628930653,-0.0747573422143828,-2.273305646512073,-0.13087043860862127,-0.3863426724775272,2.838155755900563,1.5380969287016093,0.4741043446214123,-1.0631967014757355,1.2854220588775127,0.06451636689744125,0.7671293164449878
2,448
protease
9
40
2.098814
0.035833
Q9UJ14,O75976,P28070,P28072,P49721,Q9BT78,Q99436,P20618,Q9NQW7
Functions
Panther Protein class
panther_protein_class
1,126,8,75,50,52,185,57,29
1218,898,474,126,1312,735,57,355,562,1143,440,1062,8,75,324,1605,1186,1108,615,50,2417,948,215,409,590,1032,1414,1277,1765,2071,185,629,52,2208,966,29,1,689,506,1352
-0.0747573422143828,0.14740431916148347,0.5546128696330814,1.3616582201922978,-0.13087043860862127,0.2844562241767139,2.2249146983537895,0.7407340833564946,0.4471669100474672,-0.018876472558511177,0.608035231255206,0.03677536139040555,4.4128589064029,1.885156869690082,0.7934770501751663,-0.3291429555446635,-0.04678808024453321,0.008977877355335437,0.3931382140667069,2.320717274616999,-1.9746646736460887,0.11983046945965561,1.0285153268615765,0.6612604898918479,0.4201783089598065,0.06451636689744125,-0.18721902917717162,-0.10278465967521874,-0.443793605326457,-0.7055340989840095,1.1318011406501396,0.3931382140667069,2.296818140139889,-0.8830767097251796,0.11983046945965561,2.8613102254586678,8.327942701909974,0.33890221574820123,0.5278270058270058,-0.13087043860862127
2,448
Proteasome component (PCI) domain [IPR000717]
8
17
2.093736
0.036283
Q7L2H7,O00231,Q99627,O43242,P60228,Q9BT78,Q9UBW8,Q9Y262
Sequence
InterPro Domain
interpro_domain
64,280,367,474,478,52,158,459
280,1218,474,1108,478,617,743,1280,1282,64,367,52,1884,158,689,506,459
0.8722380943101374,-0.0747573422143828,0.5546128696330814,0.008977877355335437,0.5546128696330814,0.3931382140667069,0.2844562241767139,-0.10278465967521874,-0.10278465967521874,2.080165521066943,0.7407340833564946,2.296818140139889,-0.5304492364547555,1.2343868372163067,0.33890221574820123,0.5278270058270058,0.608035231255206
2,448
Cross presentation of soluble exogenous antigens endosomes
18
36
2.089124
0.036697
Q99460,P25787,O00231,O43242,P28070,P28074,P25789,P28072,P51665,P25786,P61289,P49721,P62191,Q99436,O75832,P60900,P20618,P49720
Processes and pathways
Reactome Pathways
msigdb_reactome
629,562,280,474,8,324,440,75,442,355,420,50,590,185,265,215,57,615
280,1218,2137,898,474,265,735,57,355,562,1143,440,1062,8,75,324,1605,1186,1108,615,50,442,948,215,420,590,1032,1414,811,1277,1282,1468,185,629,891,689
0.8722380943101374,-0.0747573422143828,-0.7939909354898382,0.14740431916148347,0.5546128696330814,0.8983986553417496,0.2844562241767139,2.2249146983537895,0.7407340833564946,0.4471669100474672,-0.018876472558511177,0.608035231255206,0.03677536139040555,4.4128589064029,1.885156869690082,0.7934770501751663,-0.3291429555446635,-0.04678808024453321,0.008977877355335437,0.3931382140667069,2.320717274616999,0.608035231255206,0.11983046945965561,1.0285153268615765,0.6346723461909124,0.4201783089598065,0.06451636689744125,-0.18721902917717162,0.22979748844929848,-0.10278465967521874,-0.10278465967521874,-0.21548267738224194,1.1318011406501396,0.3931382140667069,0.17492319576901172,0.33890221574820123
2,448
Degradation of axin
18
36
2.089124
0.036697
Q99460,P25787,O00231,O43242,P28070,P28074,P25789,P28072,P51665,P25786,P61289,P49721,P62191,Q99436,O75832,P60900,P20618,P49720
Processes and pathways
Reactome Pathways
msigdb_reactome
629,562,280,474,8,324,440,75,442,355,420,50,590,185,265,215,57,615
280,1218,2137,898,474,265,735,57,355,562,1143,440,1062,8,75,324,1605,1186,1108,615,50,442,948,215,420,590,1032,1414,811,1277,1282,1468,185,629,891,689
0.8722380943101374,-0.0747573422143828,-0.7939909354898382,0.14740431916148347,0.5546128696330814,0.8983986553417496,0.2844562241767139,2.2249146983537895,0.7407340833564946,0.4471669100474672,-0.018876472558511177,0.608035231255206,0.03677536139040555,4.4128589064029,1.885156869690082,0.7934770501751663,-0.3291429555446635,-0.04678808024453321,0.008977877355335437,0.3931382140667069,2.320717274616999,0.608035231255206,0.11983046945965561,1.0285153268615765,0.6346723461909124,0.4201783089598065,0.06451636689744125,-0.18721902917717162,0.22979748844929848,-0.10278465967521874,-0.10278465967521874,-0.21548267738224194,1.1318011406501396,0.3931382140667069,0.17492319576901172,0.33890221574820123
2,448
Fatigable weakness of bulbar muscles
6
13
2.088475
0.036755
P35637,Q13148,P50995,Q15165,P06753,Q92804
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
32,330,267,23,183,31
1937,183,1857,354,32,1319,267,1370,330,1416,464,23,31
-0.5885447711477003,1.1318011406501396,-0.5304492364547555,0.7407340833564946,2.768507128882199,-0.13087043860862127,0.8983986553417496,-0.1590150898512352,0.7934770501751663,-0.18721902917717162,0.5813488413779345,3.2277043228775386,2.838155755900563
2,448
Regulation of runx3 expression and activity
19
37
2.08519
0.037052
P28070,Q13951,O75832,O00231,P61289,P49721,Q99436,P20618,P25787,P28074,P51665,P25789,P28072,P62191,P60900,Q99460,O43242,P25786,P49720
Processes and pathways
Reactome Pathways
msigdb_reactome
8,655,265,280,420,50,185,57,562,324,442,440,75,590,215,629,474,355,615
280,1218,2137,898,474,265,735,57,355,562,1143,440,1062,8,75,324,1605,1186,1108,615,50,442,948,215,420,590,1032,1414,811,1277,655,1282,1468,185,629,891,689
0.8722380943101374,-0.0747573422143828,-0.7939909354898382,0.14740431916148347,0.5546128696330814,0.8983986553417496,0.2844562241767139,2.2249146983537895,0.7407340833564946,0.4471669100474672,-0.018876472558511177,0.608035231255206,0.03677536139040555,4.4128589064029,1.885156869690082,0.7934770501751663,-0.3291429555446635,-0.04678808024453321,0.008977877355335437,0.3931382140667069,2.320717274616999,0.608035231255206,0.11983046945965561,1.0285153268615765,0.6346723461909124,0.4201783089598065,0.06451636689744125,-0.18721902917717162,0.22979748844929848,-0.10278465967521874,0.3660462944977283,-0.10278465967521874,-0.21548267738224194,1.1318011406501396,0.3931382140667069,0.17492319576901172,0.33890221574820123
2,448
Protein localization to mitochondrion
11
43
2.079226
0.037597
Q9NS69,O00170,O14737,P55786,O60830,O95831,Q99595,O96008,Q9UII2,P0DP25,Q8N4H5
Processes and pathways
GO Biological process
msigdb_gobp
3,131,4,67,11,233,54,212,159,61,95
131,1672,671,4,259,11,1965,1138,233,212,512,61,1720,979,2310,1968,1317,983,1318,765,1494,1826,67,422,840,568,363,1237,1039,1238,487,882,95,1658,54,1346,466,888,3,889,159,667,1594
1.3362880774876855,-0.3863426724775272,0.33890221574820123,5.020520990853268,0.9245131151656795,4.069391431706361,-0.6176915568126867,-0.018876472558511177,0.9766048134496434,1.0285153268615765,0.5009909364490867,2.128556440120726,-0.41503650551512866,0.09220127675854774,-1.184772259874918,-0.6176915568126867,-0.13087043860862127,0.09220127675854774,-0.13087043860862127,0.257153623658796,-0.24380646037004453,-0.5014994916724022,2.0073104645183664,0.6346723461909124,0.20238746499953386,0.4471669100474672,0.7407340833564946,-0.0747573422143828,0.06451636689744125,-0.0747573422143828,0.5546128696330814,0.17492319576901172,1.6380330471064772,-0.35771164197715183,2.272884776106456,-0.13087043860862127,0.5813488413779345,0.17492319576901172,5.810280867281288,0.17492319576901172,1.2343868372163067,0.3660462944977283,-0.30063616037720137
2,448
Proteasome
17
35
2.073301
0.038144
Q99460,P25787,O00231,O43242,P28070,P28074,P25789,P28072,P51665,P25786,P61289,P49721,P62191,Q99436,P60900,P20618,P49720
Processes and pathways
KEGG Pathways
msigdb_kegg
629,562,280,474,8,324,440,75,442,355,420,50,590,185,215,57,615
280,1218,2137,898,474,735,57,355,562,1143,440,1062,8,75,324,1605,1186,1108,615,50,442,948,215,420,590,1032,1414,811,1277,1282,1468,185,629,891,689
0.8722380943101374,-0.0747573422143828,-0.7939909354898382,0.14740431916148347,0.5546128696330814,0.2844562241767139,2.2249146983537895,0.7407340833564946,0.4471669100474672,-0.018876472558511177,0.608035231255206,0.03677536139040555,4.4128589064029,1.885156869690082,0.7934770501751663,-0.3291429555446635,-0.04678808024453321,0.008977877355335437,0.3931382140667069,2.320717274616999,0.608035231255206,0.11983046945965561,1.0285153268615765,0.6346723461909124,0.4201783089598065,0.06451636689744125,-0.18721902917717162,0.22979748844929848,-0.10278465967521874,-0.10278465967521874,-0.21548267738224194,1.1318011406501396,0.3931382140667069,0.17492319576901172,0.33890221574820123
2,448
Defective cftr causes cystic fibrosis
20
40
2.071163
0.038344
P28070,O75832,O00231,Q9BUN8,P61289,P49721,Q99436,P20618,P25787,P51665,P28074,P25789,P28072,O94905,Q9UBV2,P62191,P60900,Q99460,O43242,P25786
Processes and pathways
Reactome Pathways
msigdb_reactome
8,265,280,169,420,50,185,57,562,442,324,440,75,582,221,590,215,629,474,355
280,1218,2137,898,474,265,582,735,57,355,562,1143,440,1062,8,75,324,1605,1186,1108,615,50,442,948,1370,215,420,590,1032,1414,811,1277,1282,1468,185,629,169,221,891,689
0.8722380943101374,-0.0747573422143828,-0.7939909354898382,0.14740431916148347,0.5546128696330814,0.8983986553417496,0.4201783089598065,0.2844562241767139,2.2249146983537895,0.7407340833564946,0.4471669100474672,-0.018876472558511177,0.608035231255206,0.03677536139040555,4.4128589064029,1.885156869690082,0.7934770501751663,-0.3291429555446635,-0.04678808024453321,0.008977877355335437,0.3931382140667069,2.320717274616999,0.608035231255206,0.11983046945965561,-0.1590150898512352,1.0285153268615765,0.6346723461909124,0.4201783089598065,0.06451636689744125,-0.18721902917717162,0.22979748844929848,-0.10278465967521874,-0.10278465967521874,-0.21548267738224194,1.1318011406501396,0.3931382140667069,1.183180510648192,1.0285153268615765,0.17492319576901172,0.33890221574820123
2,448
Abc transporter disorders
20
40
2.071163
0.038344
P28070,O75832,O00231,Q9BUN8,P61289,P49721,Q99436,P20618,P25787,P28074,P51665,P25789,P28072,O94905,Q9UBV2,P62191,P60900,Q99460,O43242,P25786
Processes and pathways
Reactome Pathways
msigdb_reactome
8,265,280,169,420,50,185,57,562,324,442,440,75,582,221,590,215,629,474,355
280,1218,2137,898,474,265,582,735,57,355,562,1143,440,1062,8,75,324,1605,1186,1108,615,50,442,948,1370,215,420,590,1032,1414,811,1277,1282,1468,185,629,169,221,891,689
0.8722380943101374,-0.0747573422143828,-0.7939909354898382,0.14740431916148347,0.5546128696330814,0.8983986553417496,0.4201783089598065,0.2844562241767139,2.2249146983537895,0.7407340833564946,0.4471669100474672,-0.018876472558511177,0.608035231255206,0.03677536139040555,4.4128589064029,1.885156869690082,0.7934770501751663,-0.3291429555446635,-0.04678808024453321,0.008977877355335437,0.3931382140667069,2.320717274616999,0.608035231255206,0.11983046945965561,-0.1590150898512352,1.0285153268615765,0.6346723461909124,0.4201783089598065,0.06451636689744125,-0.18721902917717162,0.22979748844929848,-0.10278465967521874,-0.10278465967521874,-0.21548267738224194,1.1318011406501396,0.3931382140667069,1.183180510648192,1.0285153268615765,0.17492319576901172,0.33890221574820123
2,448
Auf1 hnrnp d0 binds and destabilizes mrna
21
41
2.069757
0.038475
P28070,P04792,O75832,P11940,O00231,P61289,P49721,Q99436,P20618,P25787,P28074,P51665,P25789,P28072,P62191,P60900,Q99460,O43242,Q04637,P25786,Q14103
Processes and pathways
Reactome Pathways
msigdb_reactome
8,384,265,532,280,420,50,185,57,562,324,442,440,75,590,215,629,474,104,355,392
280,1218,2137,898,474,265,384,831,532,735,57,355,562,1143,440,1062,8,75,324,1605,1186,1108,615,50,442,948,215,420,590,1032,1414,104,811,1277,392,1282,1468,185,629,891,689
0.8722380943101374,-0.0747573422143828,-0.7939909354898382,0.14740431916148347,0.5546128696330814,0.8983986553417496,0.6877999628930653,0.20238746499953386,0.4741043446214123,0.2844562241767139,2.2249146983537895,0.7407340833564946,0.4471669100474672,-0.018876472558511177,0.608035231255206,0.03677536139040555,4.4128589064029,1.885156869690082,0.7934770501751663,-0.3291429555446635,-0.04678808024453321,0.008977877355335437,0.3931382140667069,2.320717274616999,0.608035231255206,0.11983046945965561,1.0285153268615765,0.6346723461909124,0.4201783089598065,0.06451636689744125,-0.18721902917717162,1.5380969287016093,0.22979748844929848,-0.10278465967521874,0.6877999628930653,-0.10278465967521874,-0.21548267738224194,1.1318011406501396,0.3931382140667069,0.17492319576901172,0.33890221574820123
2,448
Negative regulation of ion transmembrane transporter activity
6
10
2.064895
0.038933
P28161,Q06787,P62258,P78417,Q9Y376,P0DP25
Processes and pathways
GO Biological process
msigdb_gobp
229,448,390,359,414,61
1011,61,229,498,697,390,359,448,1155,414
0.06451636689744125,2.128556440120726,1.0025825863157696,0.5278270058270058,0.3117056396225893,0.6877999628930653,0.7407340833564946,0.608035231255206,-0.018876472558511177,0.6612604898918479
2,448
Positive regulation of nf kappab transcription factor activity
8
22
2.064417
0.038978
P23396,P41440,P60900,P05067,Q9NYB0,P19474,P02786,P61088
Processes and pathways
GO Biological process
msigdb_gobp
376,357,215,88,289,121,62,285
1597,62,88,385,796,1967,121,903,376,981,984,357,215,285,1973,1417,745,1382,1546,1003,2134,289
-0.3291429555446635,2.080165521066943,1.6877650123528685,0.6877999628930653,0.22979748844929848,-0.6176915568126867,1.412273922380084,0.14740431916148347,0.7142910626044647,0.09220127675854774,0.09220127675854774,0.7407340833564946,1.0285153268615765,0.8722380943101374,-0.6176915568126867,-0.18721902917717162,0.2844562241767139,-0.1590150898512352,-0.2721908092399754,0.09220127675854774,-0.764436176582926,0.8722380943101374
2,448
Fatigable weakness of respiratory muscles
7
13
2.061933
0.039214
P35637,Q13148,P09651,Q9Y281,P50995,Q15165,Q92804
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
32,330,354,381,267,23,31
1937,1857,354,32,1319,267,1370,330,1416,464,23,31,381
-0.5885447711477003,-0.5304492364547555,0.7407340833564946,2.768507128882199,-0.13087043860862127,0.8983986553417496,-0.1590150898512352,0.7934770501751663,-0.18721902917717162,0.5813488413779345,3.2277043228775386,2.838155755900563,0.7142910626044647
2,448
Hedgehog ligand biogenesis
20
39
2.048157
0.040545
P28070,O75832,O00231,P61289,P49721,Q99436,P20618,P25787,P51665,P28074,P25789,P28072,Q9UBV2,P62191,P07237,P60900,Q99460,O43242,P25786,P49720
Processes and pathways
Reactome Pathways
msigdb_reactome
8,265,280,420,50,185,57,562,442,324,440,75,221,590,584,215,629,474,355,615
280,1218,2137,898,474,265,584,735,57,355,562,1143,440,1062,8,75,324,1605,1186,1108,615,50,442,948,1370,215,420,590,1032,1414,811,1277,1282,1468,185,629,221,891,689
0.8722380943101374,-0.0747573422143828,-0.7939909354898382,0.14740431916148347,0.5546128696330814,0.8983986553417496,0.4201783089598065,0.2844562241767139,2.2249146983537895,0.7407340833564946,0.4471669100474672,-0.018876472558511177,0.608035231255206,0.03677536139040555,4.4128589064029,1.885156869690082,0.7934770501751663,-0.3291429555446635,-0.04678808024453321,0.008977877355335437,0.3931382140667069,2.320717274616999,0.608035231255206,0.11983046945965561,-0.1590150898512352,1.0285153268615765,0.6346723461909124,0.4201783089598065,0.06451636689744125,-0.18721902917717162,0.22979748844929848,-0.10278465967521874,-0.10278465967521874,-0.21548267738224194,1.1318011406501396,0.3931382140667069,1.0285153268615765,0.17492319576901172,0.33890221574820123
2,448
Positive regulation of mrna processing
7
20
2.04327
0.041026
Q14011,P30041,P19338,P38159,P62995,Q9Y2W1,P98179
Processes and pathways
GO Biological process
msigdb_gobp
33,325,322,76,206,350,90
1135,1223,831,322,325,76,1368,206,90,1611,705,621,33,1038,916,919,454,2273,1810,350
-0.018876472558511177,-0.0747573422143828,0.20238746499953386,0.7934770501751663,0.7934770501751663,1.885156869690082,-0.1590150898512352,1.0544032957346032,1.6877650123528685,-0.3291429555446635,0.3117056396225893,0.3931382140667069,2.768507128882199,0.06451636689744125,0.14740431916148347,0.14740431916148347,0.608035231255206,-1.0631967014757355,-0.47261444201815506,0.7671293164449878
2,448
Regulation of ras by gaps
18
37
2.031479
0.042206
Q99460,P25787,O00231,O43242,P28070,P51665,P28074,P25789,P28072,P25786,P61289,P49721,P62191,Q99436,O75832,P60900,P20618,P49720
Processes and pathways
Reactome Pathways
msigdb_reactome
629,562,280,474,8,442,324,440,75,355,420,50,590,185,265,215,57,615
280,1218,2137,898,474,265,735,57,355,562,1143,440,1062,8,75,324,1605,1186,1108,615,50,442,948,215,420,590,1032,1414,811,1277,1374,1282,1468,185,629,891,689
0.8722380943101374,-0.0747573422143828,-0.7939909354898382,0.14740431916148347,0.5546128696330814,0.8983986553417496,0.2844562241767139,2.2249146983537895,0.7407340833564946,0.4471669100474672,-0.018876472558511177,0.608035231255206,0.03677536139040555,4.4128589064029,1.885156869690082,0.7934770501751663,-0.3291429555446635,-0.04678808024453321,0.008977877355335437,0.3931382140667069,2.320717274616999,0.608035231255206,0.11983046945965561,1.0285153268615765,0.6346723461909124,0.4201783089598065,0.06451636689744125,-0.18721902917717162,0.22979748844929848,-0.10278465967521874,-0.1590150898512352,-0.10278465967521874,-0.21548267738224194,1.1318011406501396,0.3931382140667069,0.17492319576901172,0.33890221574820123
2,448
Degradation of dvl
18
37
2.031479
0.042206
Q99460,P25787,O00231,O43242,P28070,P51665,P28074,P25789,P28072,P25786,P61289,P49721,P62191,Q99436,O75832,P60900,P20618,P49720
Processes and pathways
Reactome Pathways
msigdb_reactome
629,562,280,474,8,442,324,440,75,355,420,50,590,185,265,215,57,615
280,1218,2137,898,474,265,735,57,355,562,1143,440,1062,8,75,324,1605,1186,1108,615,50,442,948,215,420,590,1032,1414,811,1277,1374,1282,1468,185,629,891,689
0.8722380943101374,-0.0747573422143828,-0.7939909354898382,0.14740431916148347,0.5546128696330814,0.8983986553417496,0.2844562241767139,2.2249146983537895,0.7407340833564946,0.4471669100474672,-0.018876472558511177,0.608035231255206,0.03677536139040555,4.4128589064029,1.885156869690082,0.7934770501751663,-0.3291429555446635,-0.04678808024453321,0.008977877355335437,0.3931382140667069,2.320717274616999,0.608035231255206,0.11983046945965561,1.0285153268615765,0.6346723461909124,0.4201783089598065,0.06451636689744125,-0.18721902917717162,0.22979748844929848,-0.10278465967521874,-0.1590150898512352,-0.10278465967521874,-0.21548267738224194,1.1318011406501396,0.3931382140667069,0.17492319576901172,0.33890221574820123
2,448
Molecular transducer activity
8
23
2.024525
0.042916
O15173,Q9BUN8,Q8WTV0,Q5KU26,Q99523,P20645,P11717,Q92859
Functions
GO Molecular function
msigdb_gomf
66,169,73,142,177,299,297,18
371,66,1677,297,299,984,1639,1276,1732,2163,1198,915,142,73,18,1045,177,2422,169,855,1092,1299,2021
0.7142910626044647,2.0073104645183664,-0.3863426724775272,0.8460311580867192,0.8460311580867192,0.09220127675854774,-0.35771164197715183,-0.10278465967521874,-0.41503650551512866,-0.8236155713970702,-0.04678808024453321,0.14740431916148347,1.2854220588775127,1.9096612967942113,3.519984680570742,0.06451636689744125,1.1575125786951872,-2.007441484636362,1.183180510648192,0.20238746499953386,0.03677536139040555,-0.10278465967521874,-0.6469050293486138
2,448
Negative regulation of mrna metabolic process
25
42
2.022366
0.043139
P98175,Q08170,Q13247,Q92804,P22626,P35637,Q14011,O75494,P16989,Q8WXF0,O00422,P07910,O60506,Q06787,Q13148,P38159,P67809,Q9Y2W1,Q13242,P61978,O75534,Q16629,Q99729,P26368,Q14103
Processes and pathways
GO Biological process
msigdb_gobp
140,541,542,31,155,32,33,282,30,176,292,296,293,448,330,76,77,350,483,97,476,364,108,496,392
669,292,293,825,282,476,296,532,30,155,496,1487,32,76,97,77,140,1829,448,1538,541,1973,1974,330,1035,483,542,33,392,1236,2427,364,814,1696,1420,1337,176,1702,31,108,1049,350
0.33890221574820123,0.8460311580867192,0.8460311580867192,0.20238746499953386,0.8722380943101374,0.5546128696330814,0.8460311580867192,0.4741043446214123,2.838155755900563,1.2343868372163067,0.5278270058270058,-0.24380646037004453,2.768507128882199,1.885156869690082,1.6131083535339024,1.885156869690082,1.310876101103491,-0.5014994916724022,0.608035231255206,-0.2721908092399754,0.4741043446214123,-0.6176915568126867,-0.6176915568126867,0.7934770501751663,0.06451636689744125,0.5546128696330814,0.4741043446214123,2.768507128882199,0.6877999628930653,-0.0747573422143828,-2.273305646512073,0.7407340833564946,0.22979748844929848,-0.3863426724775272,-0.18721902917717162,-0.13087043860862127,1.1575125786951872,-0.3863426724775272,2.838155755900563,1.5380969287016093,0.06451636689744125,0.7671293164449878
2,448
Vascular process in circulatory system
11
25
2.018834
0.043504
P08183,Q9UDY2,P42892,P48506,P41440,O60568,Q9HB40,Q02952,P53985,P61586,P02786
Processes and pathways
GO Biological process
msigdb_gobp
188,370,101,441,357,508,14,501,268,55,62
1011,508,1102,62,942,188,1363,357,101,441,268,616,55,1452,501,1069,1797,543,1457,1198,2127,2047,2305,14,370
0.06451636689744125,0.5009909364490867,0.008977877355335437,2.080165521066943,0.11983046945965561,1.106045948303311,-0.1590150898512352,0.7407340833564946,1.5631405050505744,0.608035231255206,0.8983986553417496,0.3931382140667069,2.2489170176016646,-0.21548267738224194,0.5278270058270058,0.03677536139040555,-0.47261444201815506,0.4741043446214123,-0.21548267738224194,-0.04678808024453321,-0.764436176582926,-0.6761857030466238,-1.1542633725241198,3.675454238629414,0.7407340833564946
2,448
Interleukin 12 signaling
11
26
1.98259
0.047413
O00170,P52597,P26038,Q99439,P78417,O14979,Q00169,Q13126,P20700,P14174,P22626
Processes and pathways
Reactome Pathways
msigdb_reactome
131,534,342,276,359,113,567,149,375,89,155
131,113,942,1442,584,1222,732,979,89,800,375,155,1564,342,1227,2062,1534,534,834,1189,359,567,149,1112,276,891
1.3362880774876855,1.4627250220353432,0.11983046945965561,-0.21548267738224194,0.4201783089598065,-0.0747573422143828,0.2844562241767139,0.09220127675854774,1.6877650123528685,0.22979748844929848,0.7142910626044647,1.2343868372163067,-0.30063616037720137,0.7671293164449878,-0.0747573422143828,-0.7055340989840095,-0.2721908092399754,0.4741043446214123,0.20238746499953386,-0.04678808024453321,0.7407340833564946,0.4471669100474672,1.259925716446449,0.008977877355335437,0.8983986553417496,0.17492319576901172
2,448
Actin cytoskeleton reorganization
6
21
1.97725
0.048013
Q00535,P04083,Q9UQB8,P61586,O14786,Q13576
Processes and pathways
GO Biological process
msigdb_gobp
128,139,153,55,371,129
371,139,979,407,2059,2212,805,875,1189,55,987,128,1069,1732,129,706,1457,962,153,971,1009
0.7142910626044647,1.310876101103491,0.09220127675854774,0.6612604898918479,-0.7055340989840095,-0.9129143490432545,0.22979748844929848,0.17492319576901172,-0.04678808024453321,2.2489170176016646,0.09220127675854774,1.3616582201922978,0.03677536139040555,-0.41503650551512866,1.3616582201922978,0.3117056396225893,-0.21548267738224194,0.11983046945965561,1.259925716446449,0.11983046945965561,0.09220127675854774
2,448
Xerostomia
6
14
1.972723
0.048527
P35637,Q13148,P09651,P50995,Q15165,Q92804
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
32,330,354,267,23,31
1937,1857,354,32,1319,267,616,1370,330,1416,464,1116,23,31
-0.5885447711477003,-0.5304492364547555,0.7407340833564946,2.768507128882199,-0.13087043860862127,0.8983986553417496,0.3931382140667069,-0.1590150898512352,0.7934770501751663,-0.18721902917717162,0.5813488413779345,0.008977877355335437,3.2277043228775386,2.838155755900563
2,448
Abc family proteins mediated transport
24
46
1.971853
0.048626
P20042,P28070,O75832,O00231,Q9BUN8,P61289,P49721,Q99436,P20618,P08183,P25787,P51665,P28074,P25789,P28072,P05198,O94905,Q9UBV2,P62191,P60900,Q99460,O43242,P25786,Q8NE71
Processes and pathways
Reactome Pathways
msigdb_reactome
514,8,265,280,169,420,50,185,57,188,562,442,324,440,75,321,582,221,590,215,629,474,355,522
280,1218,2137,898,474,1440,265,582,321,188,735,514,57,355,562,1143,440,1062,8,75,324,1445,1605,1186,1108,615,50,442,948,1370,215,420,590,1032,1414,811,1277,1282,522,1468,185,629,169,221,891,689
0.8722380943101374,-0.0747573422143828,-0.7939909354898382,0.14740431916148347,0.5546128696330814,-0.21548267738224194,0.8983986553417496,0.4201783089598065,0.7934770501751663,1.106045948303311,0.2844562241767139,0.5009909364490867,2.2249146983537895,0.7407340833564946,0.4471669100474672,-0.018876472558511177,0.608035231255206,0.03677536139040555,4.4128589064029,1.885156869690082,0.7934770501751663,-0.21548267738224194,-0.3291429555446635,-0.04678808024453321,0.008977877355335437,0.3931382140667069,2.320717274616999,0.608035231255206,0.11983046945965561,-0.1590150898512352,1.0285153268615765,0.6346723461909124,0.4201783089598065,0.06451636689744125,-0.18721902917717162,0.22979748844929848,-0.10278465967521874,-0.10278465967521874,0.5009909364490867,-0.21548267738224194,1.1318011406501396,0.3931382140667069,1.183180510648192,1.0285153268615765,0.17492319576901172,0.33890221574820123
2,448
Negative regulation of notch4 signaling
20
39
1.968157
0.04905
P28070,O75832,O00231,P61289,P49721,Q99436,P20618,P63208,P25787,P28074,P51665,P25789,P28072,P62191,P63104,P60900,Q99460,O43242,P25786,P49720
Processes and pathways
Reactome Pathways
msigdb_reactome
8,265,280,420,50,185,57,446,562,324,442,440,75,590,463,215,629,474,355,615
280,1218,2137,898,474,265,735,57,355,562,1143,440,1062,8,75,324,1605,1186,1108,615,50,442,948,215,420,590,1032,1414,463,446,811,1277,1799,1282,1468,185,629,891,689
0.8722380943101374,-0.0747573422143828,-0.7939909354898382,0.14740431916148347,0.5546128696330814,0.8983986553417496,0.2844562241767139,2.2249146983537895,0.7407340833564946,0.4471669100474672,-0.018876472558511177,0.608035231255206,0.03677536139040555,4.4128589064029,1.885156869690082,0.7934770501751663,-0.3291429555446635,-0.04678808024453321,0.008977877355335437,0.3931382140667069,2.320717274616999,0.608035231255206,0.11983046945965561,1.0285153268615765,0.6346723461909124,0.4201783089598065,0.06451636689744125,-0.18721902917717162,0.5813488413779345,0.608035231255206,0.22979748844929848,-0.10278465967521874,-0.47261444201815506,-0.10278465967521874,-0.21548267738224194,1.1318011406501396,0.3931382140667069,0.17492319576901172,0.33890221574820123
2,448
Downstream signaling events of b cell receptor bcr
19
38
1.963363
0.049604
P28070,O75832,O00231,P61289,P49721,Q99436,P20618,P63208,P25787,P28074,P51665,P25789,P28072,P62191,P60900,Q99460,O43242,P25786,P49720
Processes and pathways
Reactome Pathways
msigdb_reactome
8,265,280,420,50,185,57,446,562,324,442,440,75,590,215,629,474,355,615
280,1218,2137,898,474,265,735,57,355,562,1143,440,1062,8,75,324,1605,1186,1108,615,50,442,948,215,420,590,1032,1414,446,811,1277,1799,1282,1468,185,629,891,689
0.8722380943101374,-0.0747573422143828,-0.7939909354898382,0.14740431916148347,0.5546128696330814,0.8983986553417496,0.2844562241767139,2.2249146983537895,0.7407340833564946,0.4471669100474672,-0.018876472558511177,0.608035231255206,0.03677536139040555,4.4128589064029,1.885156869690082,0.7934770501751663,-0.3291429555446635,-0.04678808024453321,0.008977877355335437,0.3931382140667069,2.320717274616999,0.608035231255206,0.11983046945965561,1.0285153268615765,0.6346723461909124,0.4201783089598065,0.06451636689744125,-0.18721902917717162,0.608035231255206,0.22979748844929848,-0.10278465967521874,-0.47261444201815506,-0.10278465967521874,-0.21548267738224194,1.1318011406501396,0.3931382140667069,0.17492319576901172,0.33890221574820123
2,448
Proteasome B-type subunit [IPR023333]
6
7
2.730593
0.006322
P20618,P28070,P28072,P49721,P28074,P49720
Sequence
InterPro Family
interpro_family
37,7,77,16,86,93
37,7,77,86,93,16,102
2.851762808140981,4.778560057512475,2.010629200282931,1.9242175652454103,1.866360933137052,4.122565732020271,1.8083022564928126
2,448
Proteasome core complex beta subunit complex
6
7
2.730593
0.006322
P20618,P28070,P28072,P49721,P28074,P49720
Localization
GO Cellular component
msigdb_gocc
37,7,77,16,86,93
37,7,77,86,93,16,102
2.851762808140981,4.778560057512475,2.010629200282931,1.9242175652454103,1.866360933137052,4.122565732020271,1.8083022564928126
2,448
Proteasome beta-type subunit, conserved site [IPR016050]
6
8
2.610395
0.009044
P20618,P28070,P28072,P49721,P28074,P49720
Sequence
InterPro Conserved site
interpro_conserved_site
37,7,77,16,86,93
37,478,7,77,86,93,16,102
2.851762808140981,0.5056313988484836,4.778560057512475,2.010629200282931,1.9242175652454103,1.866360933137052,4.122565732020271,1.8083022564928126
2,448
Threonine type endopeptidase activity
6
8
2.610395
0.009044
P20618,P28070,P28072,P49721,P28074,P49720
Functions
GO Molecular function
msigdb_gomf
37,7,77,16,86,93
37,478,7,77,86,93,16,102
2.851762808140981,0.5056313988484836,4.778560057512475,2.010629200282931,1.9242175652454103,1.866360933137052,4.122565732020271,1.8083022564928126
2,448
Aminoglycan metabolic process
6
12
2.060166
0.039383
P54802,O43505,P15586,Q7LGA3,P06865,P16278
Processes and pathways
GO Biological process
msigdb_gobp
133,98,38,187,89,95
98,1557,204,89,1395,341,38,95,133,1072,1028,187
1.8083022564928126,-0.30865668036302546,1.0033288868215264,1.8953143453195984,-0.20832258378727642,0.6629721446287673,2.8243575787108677,1.8373570106932495,1.4258117756144157,0.022890371442670476,0.055600103872908216,1.094835647001887
2,448
calmodulin-related
7
11
2.002241
0.045259
Q14257,O43852,P80303,Q99584,Q15293,Q02818,P30626
Functions
Panther Protein class
panther_protein_class
90,131,48,146,214,57,273
131,342,273,444,886,48,57,90,214,146,1177
1.4258117756144157,0.6629721446287673,0.7876387673800002,0.5372363553260535,0.15326352255781941,2.54799254103446,2.4362356165763077,1.8953143453195984,0.9727042106296834,1.3661511663749177,-0.042766064341452366
2,448
Regulation of actin cytoskeleton reorganization
6
9
1.996709
0.045857
Q00535,Q13576,Q9Y5K6,Q9UQB8,O14786,Q9Y624
Processes and pathways
GO Biological process
msigdb_gobp
170,106,322,88,61,498
61,482,1262,170,1073,106,88,322,498
2.38008968988982,0.5056313988484836,-0.10874313528919301,1.1858007037607743,0.022890371442670476,1.7208297348792998,1.9242175652454103,0.7254370432147011,0.5056313988484836
2,448
Threonine type peptidase activity
6
10
1.979111
0.047803
P20618,P28070,P28072,P49721,P28074,P49720
Functions
GO Molecular function
msigdb_gomf
37,7,77,16,86,93
37,478,7,77,86,93,16,1961,102,2438
2.851762808140981,0.5056313988484836,4.778560057512475,2.010629200282931,1.9242175652454103,1.866360933137052,4.122565732020271,-0.5800681913087001,1.8083022564928126,-2.8875647659564603
2,448
Proteasome, subunit alpha/beta [IPR001353]
9
14
1.97454
0.04832
P25787,Q99436,P20618,P28070,P60900,P28072,P49721,P28074,P49720
Sequence
InterPro Family
interpro_family
249,102,37,7,169,77,16,86,93
596,37,534,249,292,478,701,7,77,86,93,16,169,102
0.3785110158130981,2.851762808140981,0.44221244682449784,0.8495812998917902,0.7565705507220931,0.5056313988484836,0.2824190706827526,4.778560057512475,2.010629200282931,1.9242175652454103,1.866360933137052,4.122565732020271,1.1858007037607743,1.8083022564928126
2,448
Proteasome core complex
10
15
1.964424
0.049481
P25787,Q92530,Q99436,P20618,P28070,P60900,P28072,P49721,P28074,P49720
Localization
GO Cellular component
msigdb_gocc
249,303,102,37,7,169,77,16,86,93
596,37,534,249,292,478,701,7,77,86,93,16,169,303,102
0.3785110158130981,2.851762808140981,0.44221244682449784,0.8495812998917902,0.7565705507220931,0.5056313988484836,0.2824190706827526,4.778560057512475,2.010629200282931,1.9242175652454103,1.866360933137052,4.122565732020271,1.1858007037607743,0.7565705507220931,1.8083022564928126
2,448
cytoplasmic
152
330
4.612127
0.000004
Q8WWM7,P04792,Q7L2H7,P62861,O15144,O95373,O95861,P61586,P33176,P50995,P35579,P31948,P14174,P30260,Q04917,Q99439,Q14247,Q9UDY2,Q99460,P28072,P28074,Q9UL46,P28070,P30876,P53680,O00231,P55010,O43237,P14635,Q99436,P31689,P46379,P51665,Q02952,P78362,P60953,Q9UBF8,P60842,P61923,Q96B36,Q9H2J4,Q13685,Q15691,Q13177,Q9UJX2,P18206,O00410,Q9NT62,Q9NVZ3,O43633,P54105,Q9UQB8,Q7Z4Q2,Q15427,O76094,Q96KB5,Q8N6T3,Q9Y3A5,P84098,P98179,Q13596,O43683,Q15075,Q16637,O75340,Q9NZB2,P31150,Q9Y3C8,P40616,Q5JTV8,P49721,Q8WUM4,Q99961,Q9UN86,Q9UNM6,Q14974,P06493,P17612,P26038,P20290,P35998,P42766,P49591,P68371,P25685,P63104,Q7Z460,P20618,Q92598,Q9NVA2,Q13409,Q9UBF2,Q9UI12,P20339,Q9Y678,O43242,Q15185,O95757,P0DP25,O60869,O43592,P09132,Q96AX1,Q9UHB9,P61221,O60684,Q8TEX9,Q92973,O60749,Q9Y6G9,P25789,P17812,P62993,P25787,Q9Y5X3,P61081,O15212,P52732,Q99816,P55884,Q96A49,P11413,Q13310,Q00535,P46777,P11802,Q92530,P60228,P00338,Q13200,Q8WXX5,P42566,P09497,P30626,Q96EK5,Q7Z417,O95456,P43487,P51116,Q05682,Q92900,Q9UBB4,P50570,P13807,Q96S59,Q9UN37,P04406,Q5VYK3,P60900,Q15008,Q15418,Q06323
Localization
OpenCell Localization
opencell_localization
539,6,11,526,509,511,513,25,522,524,523,521,35,519,572,39,574,46,581,49,51,588,54,557,567,550,62,551,555,69,558,562,77,86,597,595,91,594,596,100,101,627,112,626,115,614,606,128,129,130,622,134,140,666,141,674,144,680,148,149,663,645,155,156,160,165,657,171,166,712,167,716,720,723,724,705,683,686,689,198,691,694,695,699,208,698,752,220,755,760,231,762,764,230,767,227,748,732,240,239,238,735,253,256,745,250,265,266,258,286,275,273,293,291,321,314,304,310,332,327,353,342,371,370,369,366,397,387,382,390,421,416,411,413,448,444,430,435,436,440,475,479,469,465,498,505,481,492,484,488,489,531
1483,1611,550,946,606,947,1347,1348,1949,1950,1678,509,1612,304,811,1213,1613,904,551,227,238,130,645,1571,867,250,258,239,868,1351,160,1488,1872,141,1215,1768,511,1619,430,732,513,382,1304,481,6,683,1770,1620,1048,1002,1172,735,955,411,1097,240,1991,1050,342,366,1689,1098,957,465,35,823,958,1579,555,1357,686,273,1052,614,2323,1405,1582,198,230,220,827,828,208,1310,291,1268,275,689,1360,1054,1311,1221,911,1727,54,49,51,1179,1494,519,413,557,657,558,1455,521,522,1626,1056,523,691,1010,1583,1773,1224,1537,166,1225,831,1774,2099,1408,416,694,435,1650,562,369,2041,1180,1651,833,2309,1013,1059,2371,695,1728,167,1318,1100,469,2254,1181,1539,524,779,436,77,1227,1182,1320,310,967,1585,917,1962,741,567,622,1015,62,1102,1368,327,387,918,594,484,1369,595,314,1502,745,2102,25,596,783,1503,1964,1586,1232,1462,784,1882,1017,526,1542,1415,293,698,2361,1066,699,597,785,148,149,370,1067,2153,786,86,572,440,531,2333,840,922,626,390,924,371,1070,231,1507,2025,1071,663,627,788,1280,1149,881,574,2187,790,1075,705,1022,488,1422,2074,155,748,1078,489,666,112,977,1470,1324,2311,1382,156,978,712,492,929,11,444,752,140,932,144,1596,265,716,539,421,397,797,755,854,475,266,856,1291,353,253,100,448,2194,674,1432,1117,498,69,39,581,1750,1200,2164,332,1335,720,1337,890,1976,937,1202,101,1757,128,760,129,2088,165,1638,1830,479,762,91,1256,46,256,764,1344,115,588,1297,1642,505,723,1124,724,134,1864,1906,1300,808,680,171,1643,1609,1722,1346,321,767,286
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2,448
Antigen processing ubiquitination proteasome degradation
36
77
3.675544
0.000237
Q92530,Q7Z6E9,Q16763,P48556,Q15386,P19474,Q9UJX4,Q13200,Q9ULT8,P25789,P30260,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,P61081,Q8TBC4,A0AVT1,Q99436,P63208,P51665,Q9UIQ6,P20618,Q93034,Q13867,O43242,Q9UJX2,P60900,Q15008,P55786,Q06323,Q96J02,Q14139
Processes and pathways
Reactome Pathways
msigdb_reactome
397,395,264,260,392,18,285,390,425,275,519,291,167,581,49,51,588,54,314,185,302,69,439,77,87,220,352,347,227,115,484,488,118,531,126,533
302,550,946,1766,730,227,1872,1490,648,1052,18,220,827,1310,291,1268,275,1727,54,49,51,1454,519,691,1650,260,1728,167,77,915,1102,118,484,314,968,782,969,697,1503,1463,439,661,531,390,1109,787,1702,347,533,1815,488,2189,392,264,883,630,395,634,185,397,933,352,126,69,581,1160,1940,87,115,1207,285,588,425,1720,724,1563,943
0.730826559921213,0.4409258805823772,0.14667069399718627,-0.42583141250889395,0.29436510731780724,0.9028157215260153,-0.5179988657470733,-0.21272571549189503,0.3531228099863507,0.087264561932277,3.7035378773687953,0.9313443171057458,0.23542606283924014,-0.09212329847709767,0.7595902108481608,-0.06210093493456228,0.7883139498979853,-0.3952226726312979,1.8528768241204838,1.9075802654498024,1.88024377397462,-0.182497206611748,0.47010609080532134,0.3237664369124269,-0.33417242136584113,0.8169980768047461,-0.3952226726312979,1.1017238127490079,1.6880249517622525,0.17630258634391707,0.05748948699344504,1.3268575727799916,0.4992431492624739,0.730826559921213,0.14667069399718627,0.2649184437199032,0.14667069399718627,0.3237664369124269,-0.21272571549189503,-0.182497206611748,0.5573891868193322,0.3531228099863507,0.47010609080532134,0.615366695909301,0.05748948699344504,0.2649184437199032,-0.364669859579678,0.6731783026903564,0.47010609080532134,-0.4564966412770062,0.4992431492624739,-0.8291051207987041,0.615366695909301,0.8169980768047461,0.2058875754695338,0.38243459835151017,0.615366695909301,0.38243459835151017,1.0450797177342925,0.615366695909301,0.17630258634391707,0.6731783026903564,1.298839486996753,1.7705913566526543,0.4409258805823772,0.027665838086341914,-0.5488370384270144,1.5497754824846934,1.3548410508645194,-0.002206819462379813,0.7883139498979853,0.4409258805823772,0.5863988415320117,-0.364669859579678,0.3237664369124269,-0.24300698162028928,0.17630258634391707
2,448
Class i mhc mediated antigen processing presentation
37
93
3.30638
0.000945
Q92530,Q7Z6E9,Q16763,P48556,Q15386,P19474,Q9UJX4,Q13200,Q9ULT8,P25789,P30260,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,P61081,Q8TBC4,A0AVT1,Q99436,P63208,P51665,Q9UIQ6,P20618,Q93034,Q13867,O43242,Q9UJX2,P60900,Q15008,P55786,Q15436,Q06323,Q96J02,Q14139
Processes and pathways
Reactome Pathways
msigdb_reactome
397,395,264,260,392,18,285,390,425,275,519,291,167,581,49,51,588,54,314,185,302,69,439,77,87,220,352,347,227,115,484,488,118,123,531,126,533
302,1210,550,946,1766,730,227,1572,1872,1490,648,1215,682,1170,1575,653,1533,1052,18,220,827,1310,291,1268,275,1137,1361,1727,54,49,51,1454,2269,519,691,1650,260,1728,167,2286,77,915,1229,1102,118,1996,484,314,968,782,969,970,697,1503,1463,439,661,531,390,1109,787,1702,347,533,1815,488,2189,392,123,264,883,630,395,634,185,397,933,352,126,69,581,1160,1940,87,115,1207,285,588,425,1720,724,1563,943
0.730826559921213,-0.03212892744333096,0.4409258805823772,0.14667069399718627,-0.42583141250889395,0.29436510731780724,0.9028157215260153,-0.27334151033073334,-0.5179988657470733,-0.21272571549189503,0.3531228099863507,-0.03212892744333096,0.3237664369124269,-0.002206819462379813,-0.27334151033073334,0.3531228099863507,-0.24300698162028928,0.087264561932277,3.7035378773687953,0.9313443171057458,0.23542606283924014,-0.09212329847709767,0.7595902108481608,-0.06210093493456228,0.7883139498979853,0.027665838086341914,-0.12219648225605645,-0.3952226726312979,1.8528768241204838,1.9075802654498024,1.88024377397462,-0.182497206611748,-0.9553250615605502,0.47010609080532134,0.3237664369124269,-0.33417242136584113,0.8169980768047461,-0.3952226726312979,1.1017238127490079,-0.987047828674115,1.6880249517622525,0.17630258634391707,-0.03212892744333096,0.05748948699344504,1.3268575727799916,-0.6106905307608944,0.4992431492624739,0.730826559921213,0.14667069399718627,0.2649184437199032,0.14667069399718627,0.14667069399718627,0.3237664369124269,-0.21272571549189503,-0.182497206611748,0.5573891868193322,0.3531228099863507,0.47010609080532134,0.615366695909301,0.05748948699344504,0.2649184437199032,-0.364669859579678,0.6731783026903564,0.47010609080532134,-0.4564966412770062,0.4992431492624739,-0.8291051207987041,0.615366695909301,1.298839486996753,0.8169980768047461,0.2058875754695338,0.38243459835151017,0.615366695909301,0.38243459835151017,1.0450797177342925,0.615366695909301,0.17630258634391707,0.6731783026903564,1.298839486996753,1.7705913566526543,0.4409258805823772,0.027665838086341914,-0.5488370384270144,1.5497754824846934,1.3548410508645194,-0.002206819462379813,0.7883139498979853,0.4409258805823772,0.5863988415320117,-0.364669859579678,0.3237664369124269,-0.24300698162028928,0.17630258634391707
2,448
Auf1 hnrnp d0 binds and destabilizes mrna
20
41
3.297861
0.000974
P04792,P48556,Q13200,Q04637,P25789,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,Q99436,P51665,P20618,O43242,P60900,Q15008,Q06323,Q92530
Processes and pathways
Reactome Pathways
msigdb_reactome
6,260,390,278,275,291,167,581,49,51,588,54,69,77,220,227,484,488,531,397
550,946,1766,730,227,1872,6,1050,1051,1052,220,1310,291,1268,275,1727,54,49,51,691,1650,260,1728,167,77,1102,484,969,697,1503,1463,278,531,390,880,488,397,69,581,588,724
0.4409258805823772,0.14667069399718627,-0.42583141250889395,0.29436510731780724,0.9028157215260153,-0.5179988657470733,5.931560240339164,0.087264561932277,0.087264561932277,0.087264561932277,0.9313443171057458,-0.09212329847709767,0.7595902108481608,-0.06210093493456228,0.7883139498979853,-0.3952226726312979,1.8528768241204838,1.9075802654498024,1.88024377397462,0.3237664369124269,-0.33417242136584113,0.8169980768047461,-0.3952226726312979,1.1017238127490079,1.6880249517622525,0.05748948699344504,0.4992431492624739,0.14667069399718627,0.3237664369124269,-0.21272571549189503,-0.182497206611748,0.7883139498979853,0.47010609080532134,0.615366695909301,0.2058875754695338,0.4992431492624739,0.615366695909301,1.7705913566526543,0.4409258805823772,0.4409258805823772,0.3237664369124269
2,448
Endopeptidase complex
24
47
3.294443
0.000986
P04792,P48556,Q15386,Q13200,P25789,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,P54727,Q99436,P51665,O43396,P20618,Q15008,O43242,Q5VYK3,P60900,P17655,Q06323,Q92530
Localization
GO Cellular component
msigdb_gocc
6,260,392,390,275,291,167,581,49,51,588,54,312,69,77,323,220,488,227,492,484,367,531,397
550,946,1766,730,227,323,1872,6,367,1052,220,1310,291,1268,275,1727,54,49,51,691,1650,260,1728,167,77,1926,312,1102,1368,484,969,697,1503,1463,531,390,488,392,845,492,397,799,69,581,588,724,727
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2,448