term stringlengths 2 121 | overlap int64 6 281 | setsize int64 7 499 | score float64 1.96 10.6 | pval float64 0 0.05 | edge stringlengths 41 1.97k | type stringclasses 5 values | subtype stringclasses 24 values | subtype_key stringclasses 24 values | edge_idxs stringlengths 11 1.17k | ann_idxs stringlengths 19 2.31k | ann_vals stringlengths 124 9.94k | sig_size int64 2.2k 3.73k |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Rhoa gtpase cycle | 16 | 42 | 2.263583 | 0.0236 | P51572,Q13190,P30519,P42167,Q8TAA9,Q96HY6,Q14739,Q14155,O15173,P49257,Q15904,P27105,Q8NBN3,Q5T8D3,P42166,Q96CS3 | Processes and pathways | Reactome Pathways | msigdb_reactome | 378,379,15,137,331,435,63,380,1,371,150,243,56,413,475,415 | 2835,1,539,2487,1772,793,911,856,2465,243,998,15,475,137,983,371,378,1182,2331,706,379,1891,380,1001,63,150,2646,1659,413,986,56,331,1169,2622,1584,415,435,1156,2247,2674,1369,1834 | -1.3177877513267882,2.7865963021561844,0.7963041792747236,-0.790158603325098,-0.3640784829626108,0.37848281033276193,0.2587087137570336,0.3134268623516243,-0.7642758044694951,1.5509554899927154,0.17018204434377465,2.7865963021561844,0.9166188980730294,1.9711455855672875,0.19242808953692997,1.1412628685006496,1.1316526237207287,0.012263503817357187,-0.6745226915843691,0.5066672688737386,1.1316526237207287,-0.4249537836469441,1.1316526237207287,0.17018204434377465,2.5721527129844883,1.91146638965221,-0.9477598961504297,-0.2917940370002244,1.044527674490626,0.19242808953692997,2.6725377054663495,1.2743671261934335,0.02367335660523504,-0.9079828307436817,-0.24405890873575004,1.044527674490626,1.0152293506995245,0.046432220019570425,-0.6111934918254137,-0.9744205679131902,-0.11460847744939862,-0.38835818423016644 | 2,948 |
Abnormal activity of mitochondrial respiratory chain | 20 | 53 | 2.263552 | 0.023602 | Q9NPL8,P51970,Q9P0J0,Q9Y2R0,Q9Y584,O43676,Q3ZCQ8,P21912,Q7KZN9,Q70HW3,O96000,Q86Y39,O60783,Q9UBX3,P03886,Q8IUX1,Q9Y6M9,P13073,Q96CU9,Q9NX14 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 256,518,41,46,47,4,545,300,177,50,59,64,446,74,82,84,472,100,237,375 | 909,4,2812,446,886,841,1262,1594,59,82,1842,100,1987,620,300,2652,2855,1724,1688,1418,2827,518,1316,1943,1914,2659,1540,545,2211,2699,50,177,64,84,1321,1292,237,1269,1239,2703,1326,867,256,375,1340,41,2183,74,46,563,1591,47,472 | 0.2587087137570336,2.7865963021561844,-1.219695410183742,0.9661083033658407,0.29159522794570475,0.3243150746047458,-0.04509319702796837,-0.2559590292516626,2.6263862300362906,2.3669143039585743,-0.4005331441008264,2.2619609417326685,-0.48642267214362184,0.6427402454712744,1.3399348389815091,-0.9610758787021824,-1.3888295718761405,-0.3398917455531721,-0.3157971881285571,-0.14965257503761473,-1.2615427802704529,0.8265899167457623,-0.07975612003119716,-0.4617630665446928,-0.43719966585492787,-0.9610758787021824,-0.22032543356056838,0.7861778054768966,-0.5986041602975515,-1.0146282533851079,2.748783614171598,1.7730558021420846,2.5721527129844883,2.3508713480882792,-0.07975612003119716,-0.05662659699134138,1.5779971133556963,-0.04509319702796837,-0.022088703724805023,-1.0146282533851079,-0.07975612003119716,0.3134268623516243,1.5147299640350362,1.1412628685006496,-0.09135241125892804,2.7865963021561844,-0.57350110142299,2.4465744240784657,2.7865963021561844,0.7658780462552383,-0.24405890873575004,2.7865963021561844,0.9265465415241949 | 2,948 |
Abnormal brainstem mri signal intensity | 10 | 21 | 2.262015 | 0.023697 | Q9NPL8,Q86Y39,O95831,Q96CU9,P03886,Q8IUX1,Q9NX14,Q9Y6M9,O96000,O43676 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 256,64,232,237,82,84,375,472,59,4 | 4,886,841,1262,232,59,82,1987,2652,774,2827,64,84,1321,1292,237,256,375,1340,563,472 | 2.7865963021561844,0.29159522794570475,0.3243150746047458,-0.04509319702796837,1.5869868897272525,2.6263862300362906,2.3669143039585743,-0.48642267214362184,-0.9610758787021824,0.4000236057676474,-1.2615427802704529,2.5721527129844883,2.3508713480882792,-0.07975612003119716,-0.05662659699134138,1.5779971133556963,1.5147299640350362,1.1412628685006496,-0.09135241125892804,0.7658780462552383,0.9265465415241949 | 2,948 |
Membrane insertase activity | 6 | 8 | 2.261643 | 0.023719 | Q15006,Q9Y5J7,P62072,Q9NPA0,Q8N4V1,Q15070 | Functions | GO Molecular function | msigdb_gomf | 449,131,484,178,87,55 | 484,449,55,581,87,1088,178,131 | 0.9066762741167944,0.9661083033658407,2.6878537725796168,0.7045987780437237,2.342835848946172,0.10297815590527408,1.7730558021420846,2.030306552404175 | 2,948 |
Transition metal ion transport | 8 | 16 | 2.26002 | 0.02382 | Q8TAD4,Q9HC07,Q9H9B4,Q15043,P35670,O15173,Q9HD20,Q8N4V1 | Processes and pathways | GO Biological process | msigdb_gobp | 136,35,427,395,429,1,213,87 | 1,441,856,429,831,918,1889,742,607,395,87,136,1326,427,35,213 | 2.7865963021561844,0.9956247465412347,0.3134268623516243,1.0152293506995245,0.3351849748792302,0.2587087137570336,-0.4249537836469441,0.4535644598837149,0.6634248673505861,1.083391393192826,2.342835848946172,1.979628647593098,-0.07975612003119716,1.0250098889275254,2.7865963021561844,1.6406749935197982 | 2,948 |
Cholesterol metabolism | 9 | 23 | 2.256834 | 0.024018 | P04062,P14324,O15118,Q16850,Q15392,Q15800,P04035,P37268,Q14739 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 229,351,167,135,111,49,119,158,63 | 167,1053,1214,119,229,351,2651,368,158,1420,594,2138,2867,1657,2559,63,2764,111,1361,49,135,948,1413 | 1.8252912358654134,0.12545767674967293,-0.010617445326537883,2.1388354236994354,1.604930508493485,1.1891065386883313,-0.9610758787021824,1.150859217416934,1.8685154984719228,-0.14965257503761473,0.6840442269321578,-0.5609871514945417,-1.4751868426259223,-0.2917940370002244,-0.842249330451033,2.5721527129844883,-1.1094770400206861,2.1636379759404285,-0.11460847744939862,2.748783614171598,1.979628647593098,0.2366908459404441,-0.1379497605933577 | 2,948 |
Cytochrome complex | 6 | 18 | 2.252943 | 0.024263 | O14949,P00403,P13073,Q7KZN9,Q9UDW1,P14406 | Localization | GO Cellular component | msigdb_gocc | 0,65,100,177,42,12 | 909,321,0,65,1040,1079,871,100,12,486,1278,620,720,1476,2695,177,42,1126 | 0.2587087137570336,1.3025465155694014,2.7865963021561844,2.556579298083099,0.13666798971763972,0.10297815590527408,0.30252026972797935,2.2619609417326685,2.7865963021561844,0.8967186195513424,-0.05662659699134138,0.6427402454712744,0.4854782032901361,-0.18489076228795653,-1.0146282533851079,1.7730558021420846,2.7865963021561844,0.06911049008272775 | 2,948 |
Selective autophagy | 13 | 28 | 2.238235 | 0.025206 | P21796,Q9UMX0,Q99623,Q96HY6,O15269,P12235,O43464,Q5THJ4,Q9Y679,P05141,Q16543,Q5T8D3,P27544 | Processes and pathways | GO Biological process | msigdb_gobp | 13,655,298,435,457,242,659,254,634,216,478,413,447 | 1701,457,1037,659,1331,661,1416,1841,216,242,13,1705,447,1654,892,817,1656,478,413,254,2214,435,298,2470,1173,655,2705,634 | -0.32783299293488966,0.946357086039273,0.13666798971763972,0.5802901932522984,-0.09135241125892804,0.569823459438201,-0.14965257503761473,-0.4005331441008264,1.6317566291206993,1.5599814492167579,2.7865963021561844,-0.32783299293488966,0.9661083033658407,-0.2917940370002244,0.2806516678173481,0.34603663117384015,-0.2917940370002244,0.9166188980730294,1.044527674490626,1.5147299640350362,-0.5986041602975515,1.0152293506995245,1.3585507904603225,-0.7642758044694951,0.02367335660523504,0.5907401452154999,-1.0146282533851079,0.6219899025279677 | 2,948 |
Cardiac conduction abnormality | 8 | 29 | 2.235723 | 0.02537 | P00403,P00846,P23786,Q9HD47,P06280,P03886,Q9H490,P50402 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 65,10,14,36,270,82,190,223 | 679,450,841,2777,65,10,779,82,270,648,2465,1986,300,14,1724,526,2271,762,1218,223,2755,2726,1827,2645,978,1154,2385,190,36 | 0.5488394069573772,0.9562400860282577,0.3243150746047458,-1.1368469678810535,2.556579298083099,2.7865963021561844,0.3892621629388748,2.3669143039585743,1.450861147058744,0.5907401452154999,-0.7642758044694951,-0.48642267214362184,1.3399348389815091,2.7865963021561844,-0.3398917455531721,0.8165101819823601,-0.6364483212823517,0.4214930245328858,-0.010617445326537883,1.6228264499658536,-1.0958375623669119,-1.0550993024853272,-0.38835818423016644,-0.9477598961504297,0.20352233615489593,0.046432220019570425,-0.7000350378719272,1.7467862291402754,2.7865963021561844 | 2,948 |
Mitochondrial biogenesis | 16 | 35 | 2.227944 | 0.025884 | Q16891,O75431,P00846,P24539,P06576,P18859,Q9Y512,Q5XKP0,P56385,Q9BUR5,Q9NX63,Q9NVH1,O75964,Q04837,Q13505,Q6UXV4 | Processes and pathways | Reactome Pathways | msigdb_reactome | 259,221,10,71,516,524,304,203,206,51,533,467,116,564,153,281 | 746,221,958,116,670,10,2430,516,1346,524,71,2049,671,2606,2574,2725,2829,753,1420,580,206,1776,564,153,2192,1071,259,203,281,1762,2896,51,467,533,304 | 0.4428915878012244,1.6228264499658536,0.21459749616700588,2.1471129220217553,0.5593398840306882,2.7865963021561844,-0.7385000591107437,0.8265899167457623,-0.10296983526705214,0.8165101819823601,2.4623968296549257,-0.5235943001305398,0.5593398840306882,-0.8947803220762554,-0.8684592789776662,-1.0550993024853272,-1.2755556472837077,0.4322011307611214,-0.14965257503761473,0.7045987780437237,1.6673595426785333,-0.3640784829626108,0.7557045532861382,1.8857284450931486,-0.5860400673875427,0.11422775748782157,1.5056429783185705,1.6850907972023321,1.4048651179707776,-0.3519735430085323,-1.666616164476735,2.748783614171598,0.9364592543163456,0.8165101819823601,1.3399348389815091 | 2,948 |
transfer/carrier protein | 8 | 12 | 2.227116 | 0.02594 | O15127,P17900,Q969E2,P12235,P05141,P12236,Q9Y5M8,Q5T8D3 | Functions | Panther Protein class | panther_protein_class | 68,79,403,242,216,88,61,413 | 534,1516,68,2604,216,242,88,79,1117,413,403,61 | 0.8064149537544595,-0.20849189523024658,2.5017952660766634,-0.8947803220762554,1.6317566291206993,1.5599814492167579,2.3347909701503586,2.390908991266633,0.06911049008272775,1.044527674490626,1.063988051826483,2.603195119929511 | 2,948 |
Endoplasmic reticulum tubular network organization | 6 | 11 | 2.225699 | 0.026034 | Q9H6H4,P57088,Q15041,Q9NQC3,Q8NHH9,O95197 | Processes and pathways | GO Biological process | msigdb_gobp | 325,258,134,38,176,58 | 58,258,430,134,1306,176,768,996,325,598,38 | 2.6495002369252414,1.5056429783185705,1.0152293506995245,2.00501467030959,-0.06818087672087327,1.7817897223618568,0.4214930245328858,0.18131468338625611,1.3025465155694014,0.6840442269321578,2.7865963021561844 | 2,948 |
Dementia | 28 | 57 | 2.224938 | 0.026085 | O43681,P20700,P36543,P00846,P22626,P35637,Q96RL7,O15118,Q14108,P21912,P35670,Q9Y487,Q9NQZ5,Q9UBB4,P27544,P00403,P17900,Q13510,Q9NZJ7,P03886,O60313,P61916,O60220,O76024,P04062,P07602,P06865,Q9Y287 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 385,635,526,10,551,296,552,167,20,300,429,182,186,570,447,65,79,80,208,82,210,594,214,482,229,121,377,642 | 969,167,659,385,214,210,1881,482,912,65,10,82,229,2803,959,377,121,858,2638,79,635,300,551,2503,447,1724,1056,296,429,526,2271,951,1927,1558,2110,594,2086,1301,1946,80,20,1252,1134,1807,881,716,1999,1811,552,2851,186,2852,208,570,1193,642,182 | 0.20352233615489593,1.8252912358654134,0.5802901932522984,1.1123902679624265,1.6317566291206993,1.6495815776906195,-0.4249537836469441,0.9066762741167944,0.2587087137570336,2.556579298083099,2.7865963021561844,2.3669143039585743,1.604930508493485,-1.1919549279763493,0.21459749616700588,1.1316526237207287,2.1305479088449735,0.3134268623516243,-0.9344724839888465,2.390908991266633,0.6115899409245514,1.3399348389815091,0.7760357790137803,-0.8031404562248112,0.9661083033658407,-0.3398917455531721,0.12545767674967293,1.3585507904603225,1.0152293506995245,0.8165101819823601,-0.6364483212823517,0.22565364207130884,-0.4494693924997594,-0.2321810742152696,-0.5484981074488348,0.6840442269321578,-0.5360338598815546,-0.06818087672087327,-0.4617630665446928,2.3749218087203583,2.7865963021561844,-0.03358059353370555,0.057781389746196045,-0.376206663719245,0.30252026972797935,0.496081370665703,-0.48642267214362184,-0.376206663719245,0.7760357790137803,-1.374554921863492,1.755554087887899,-1.374554921863492,1.6673595426785333,0.7455152459043228,0.012263503817357187,0.6115899409245514,1.764310601412421 | 2,948 |
Amino acid transmembrane transporter activity | 10 | 11 | 2.222897 | 0.026223 | Q96NB2,O75746,Q96QD8,Q9H9B4,Q9H936,P30825,Q9Y619,Q15758,Q9H2H9,Q9UJS0 | Functions | GO Molecular function | msigdb_gomf | 416,420,201,427,462,205,174,650,641,513 | 420,713,205,650,416,201,641,462,427,513,174 | 1.034775981150425,0.496081370665703,1.6673595426785333,0.5907401452154999,1.044527674490626,1.7027756119300326,0.6115899409245514,0.946357086039273,1.0250098889275254,0.8366542105550503,1.790512394214301 | 2,948 |
Amyloid precursor protein catabolic process | 7 | 19 | 2.221085 | 0.026345 | O75298,Q92542,Q9NQC3,Q16799,Q15392,Q96P70,O95197 | Processes and pathways | GO Biological process | msigdb_gobp | 9,228,38,21,111,248,58 | 1772,9,58,844,2780,1991,343,1617,519,1891,2439,1319,1001,111,21,228,248,1171,38 | -0.3640784829626108,2.7865963021561844,2.6495002369252414,0.3243150746047458,-1.1368469678810535,-0.48642267214362184,1.2271350371463017,-0.267881528486022,0.8265899167457623,-0.4249537836469441,-0.7385000591107437,-0.07975612003119716,0.17018204434377465,2.1636379759404285,2.7865963021561844,1.6138844213708674,1.5419173980870937,0.02367335660523504,2.7865963021561844 | 2,948 |
Protein exit from endoplasmic reticulum | 12 | 22 | 2.219574 | 0.026448 | O15260,Q9BUN8,Q8TCT9,Q9GZP9,Q9HD47,Q9BVK6,P49257,Q9Y679,Q86TM6,Q9NR31,P51572,Q96CS3 | Processes and pathways | GO Biological process | msigdb_gobp | 515,30,200,616,36,308,371,634,217,480,378,415 | 1036,515,1245,371,378,2110,1618,217,2216,2241,200,1170,1998,415,30,308,616,691,36,480,634,1115 | 0.13666798971763972,0.8265899167457623,-0.03358059353370555,1.1412628685006496,1.1316526237207287,-0.5484981074488348,-0.267881528486022,1.6317566291206993,-0.5986041602975515,-0.6111934918254137,1.7027756119300326,0.02367335660523504,-0.48642267214362184,1.044527674490626,2.7865963021561844,1.3306073711486148,0.6530907427544451,0.5383219678135337,2.7865963021561844,0.9166188980730294,0.6219899025279677,0.0804195993803759 | 2,948 |
Hepatic failure | 21 | 46 | 2.214177 | 0.026817 | Q6PGP7,P40855,Q9H9E3,P00846,P23786,O15118,Q9Y5L0,Q9Y619,P35670,O15460,P22830,O75845,O75381,Q13510,P03886,A2RRP1,Q13043,P01889,Q10713,P04062,P50416 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 665,278,549,10,14,167,554,174,429,568,322,202,336,80,82,339,466,602,353,229,120 | 339,167,568,679,1958,336,202,1818,10,602,82,229,1721,2129,1040,887,1279,322,14,998,2915,429,2438,278,1129,2507,120,2254,1776,353,466,80,1581,894,962,665,1239,867,549,2442,2473,1514,1834,1194,554,174 | 1.2366082942318883,1.8252912358654134,0.7455152459043228,0.5488394069573772,-0.4740807916428801,1.2555144652951549,1.6939389927188315,-0.38835818423016644,2.7865963021561844,0.6737426764494571,2.3669143039585743,1.604930508493485,-0.3398917455531721,-0.5609871514945417,0.13666798971763972,0.29159522794570475,-0.05662659699134138,1.3025465155694014,2.7865963021561844,0.17018204434377465,-1.957798307493796,1.0152293506995245,-0.7385000591107437,1.4140896324394103,0.057781389746196045,-0.8031404562248112,2.1388354236994354,-0.6238081744136992,-0.3640784829626108,1.1891065386883313,0.9364592543163456,2.3749218087203583,-0.24405890873575004,0.2806516678173481,0.21459749616700588,0.569823459438201,-0.022088703724805023,0.3134268623516243,0.7861778054768966,-0.7385000591107437,-0.7642758044694951,-0.19668036826606938,-0.38835818423016644,0.012263503817357187,0.7760357790137803,1.790512394214301 | 2,948 |
Glycosaminoglycan metabolism | 7 | 13 | 2.212501 | 0.026932 | O43505,Q7LGA3,P54802,P16278,Q8NCH0,Q8TB61,P06865 | Processes and pathways | Reactome Pathways | msigdb_reactome | 168,199,110,271,48,124,377 | 838,168,1453,377,1866,843,503,271,110,199,48,124,1526 | 0.3243150746047458,1.8252912358654134,-0.17312298748902247,1.1316526237207287,-0.4127316435962459,0.3243150746047458,0.856736683979823,1.450861147058744,2.1883510978830576,1.7027756119300326,2.7714957902295567,2.1222503506021453,-0.20849189523024658 | 2,948 |
Nuclear inner membrane | 7 | 19 | 2.212492 | 0.026933 | Q8IXM6,Q99720,P50402,O94901,Q9H1E5,O75844,Q14739 | Localization | GO Cellular component | msigdb_gocc | 66,28,223,261,53,93,63 | 93,261,635,1688,951,223,1994,693,724,1018,63,346,66,978,28,2385,53,629,769 | 2.3186729764700886,1.487432024700378,0.6115899409245514,-0.3157971881285571,0.22565364207130884,1.6228264499658536,-0.48642267214362184,0.5277875058595842,0.4854782032901361,0.15903009861468134,2.5721527129844883,1.217648275818038,2.5487794620652107,0.20352233615489593,2.7865963021561844,-0.7000350378719272,2.7259972750389694,0.6323733180004086,0.4214930245328858 | 2,948 |
Abnormality of pulmonary circulation | 8 | 27 | 2.210692 | 0.027057 | P00403,P04062,Q9NZ08,Q6NUK1,Q14108,P03886,O96000,O75844 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 65,229,101,268,20,82,59,93 | 2777,93,1740,59,65,602,779,82,229,2643,620,2878,902,1649,2049,1843,1358,809,518,1966,20,2596,2401,268,285,1411,101 | -1.1368469678810535,2.3186729764700886,-0.3519735430085323,2.6263862300362906,2.556579298083099,0.6737426764494571,0.3892621629388748,2.3669143039585743,1.604930508493485,-0.9477598961504297,0.6427402454712744,-1.533447071350304,0.26968951975298766,-0.2917940370002244,-0.5235943001305398,-0.4005331441008264,-0.11460847744939862,0.3568701110972379,0.8265899167457623,-0.4740807916428801,2.7865963021561844,-0.8816058486119072,-0.7128303925048417,1.4600225814271781,1.3956278719322963,-0.1379497605933577,2.2619609417326685 | 2,948 |
Fetal distress | 10 | 25 | 2.209904 | 0.027112 | Q9NPL8,Q86Y39,Q9NVI7,Q96CU9,P03886,Q8IUX1,Q9NX14,Q9Y6M9,O96000,O43676 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 256,64,389,237,82,84,375,472,59,4 | 4,886,841,1262,2798,59,82,2046,1987,1649,2652,1231,2827,1751,64,84,1321,237,1270,256,389,375,1340,563,472 | 2.7865963021561844,0.29159522794570475,0.3243150746047458,-0.04509319702796837,-1.178131544305962,2.6263862300362906,2.3669143039585743,-0.5235943001305398,-0.48642267214362184,-0.2917940370002244,-0.9610758787021824,-0.022088703724805023,-1.2615427802704529,-0.3519735430085323,2.5721527129844883,2.3508713480882792,-0.07975612003119716,1.5779971133556963,-0.04509319702796837,1.5147299640350362,1.1123902679624265,1.1412628685006496,-0.09135241125892804,0.7658780462552383,0.9265465415241949 | 2,948 |
Golgi stack | 16 | 30 | 2.208743 | 0.027193 | Q10713,Q15363,Q9UL25,P04439,P51572,P0CG08,Q10472,Q9H4A5,Q10471,Q99523,P61106,O00461,Q8NBN3,Q14789,Q9H4A6,Q8TBA6 | Localization | GO Cellular component | msigdb_gocc | 353,97,771,376,378,579,265,617,715,460,764,115,56,381,313,414 | 115,1791,2158,376,579,2167,378,764,918,1580,2904,876,715,265,353,381,1002,97,56,414,1169,460,2720,617,313,771,967,1789,797,1115 | 2.1471129220217553,-0.376206663719245,-0.57350110142299,1.1316526237207287,0.7045987780437237,-0.57350110142299,1.1316526237207287,0.4214930245328858,0.2587087137570336,-0.24405890873575004,-1.7722601515679126,0.30252026972797935,0.496081370665703,1.4691715140650488,1.1891065386883313,1.1316526237207287,0.17018204434377465,2.310599812778192,2.6725377054663495,1.044527674490626,0.02367335660523504,0.946357086039273,-1.0415794544601462,0.6530907427544451,1.3212668549703706,0.4107672045221039,0.21459749616700588,-0.3640784829626108,0.37848281033276193,0.0804195993803759 | 2,948 |
Cholesterol biosynthesis | 8 | 17 | 2.207269 | 0.027295 | Q16850,O75845,Q15392,Q15800,P04035,Q14534,P37268,Q14739 | Processes and pathways | Reactome Pathways | msigdb_reactome | 135,202,111,49,119,91,158,63 | 202,119,351,158,1519,2867,1657,2559,91,63,2764,111,1361,49,135,1048,948 | 1.6939389927188315,2.1388354236994354,1.1891065386883313,1.8685154984719228,-0.20849189523024658,-1.4751868426259223,-0.2917940370002244,-0.842249330451033,2.3267366874432778,2.5721527129844883,-1.1094770400206861,2.1636379759404285,-0.11460847744939862,2.748783614171598,1.979628647593098,0.13666798971763972,0.2366908459404441 | 2,948 |
Abnormal mitochondria in muscle tissue | 10 | 21 | 2.20422 | 0.027509 | Q9NPL8,Q86Y39,P00403,Q96CU9,P03886,Q8IUX1,Q9NX14,Q9Y6M9,O96000,O43676 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 256,64,65,237,82,84,375,472,59,4 | 4,886,841,1262,59,65,82,1987,2652,1724,2827,64,84,1321,237,256,375,1340,563,657,472 | 2.7865963021561844,0.29159522794570475,0.3243150746047458,-0.04509319702796837,2.6263862300362906,2.556579298083099,2.3669143039585743,-0.48642267214362184,-0.9610758787021824,-0.3398917455531721,-1.2615427802704529,2.5721527129844883,2.3508713480882792,-0.07975612003119716,1.5779971133556963,1.5147299640350362,1.1412628685006496,-0.09135241125892804,0.7658780462552383,0.5907401452154999,0.9265465415241949 | 2,948 |
Cis golgi network | 7 | 13 | 2.203494 | 0.02756 | Q8TBA6,Q9Y3A6,O00461,P24390,P49755,Q14789,O43731 | Localization | GO Cellular component | msigdb_gocc | 414,469,115,54,343,381,5 | 115,1644,5,54,343,918,876,381,414,1169,1491,562,469 | 2.1471129220217553,-0.2917940370002244,2.7865963021561844,2.718385255179428,1.2271350371463017,0.2587087137570336,0.30252026972797935,1.1316526237207287,1.044527674490626,0.02367335660523504,-0.18489076228795653,0.7658780462552383,0.9364592543163456 | 2,948 |
RNA recognition motif domain [IPR000504] | 46 | 110 | 3.960002 | 0.000075 | P31943,Q15056,Q8WUA2,Q15233,O14979,P55795,P98175,Q9GZT3,Q86U42,Q16629,P52272,P07910,P19338,Q08170,O43390,Q96E39,Q92804,P43243,P51991,Q8N684,Q96PK6,P98179,Q9Y5S9,P31942,P62995,Q9P2K5,Q07955,Q13242,Q96T58,Q99729,P23246,Q14103,O60506,Q14011,Q13595,P52597,Q01844,P22626,Q9BWF3,P38159,P09651,Q8WVV9,P35637,P23588,Q9Y4C8,O75494 | Sequence | InterPro Domain | interpro_domain | 375,255,521,517,132,514,515,146,276,407,535,401,532,163,169,173,180,424,182,444,188,61,465,195,197,199,324,77,208,209,333,335,215,93,346,225,226,224,239,109,359,242,115,120,527,127 | 1046,132,969,2121,169,1382,215,127,1162,2428,1340,401,930,1092,863,359,660,1670,1345,532,224,333,120,2092,1392,935,195,375,2096,115,109,2559,424,1480,182,535,225,663,514,1141,197,871,515,61,2642,622,226,2304,324,163,835,2018,563,77,2139,717,1550,1172,346,93,335,2245,1601,1764,1725,255,517,1726,988,407,1212,2275,1446,1972,276,1267,1366,805,444,1185,521,242,2827,722,180,1324,173,1834,694,188,208,209,239,1561,2359,146,1702,1703,1331,755,1002,199,1742,2933,1236,2046,634,527,465,2160 | 0.14670037120281113,1.4212012137589964,0.18802891238331532,-0.35452613486786577,1.202380291141655,-0.01926704960112091,1.0423270044122548,1.4806368149043725,0.08458639893558295,-0.5665017880289501,0.001537164702395684,0.6589210414523182,0.20866925843125922,0.12601197226717611,0.2499026019446144,0.7197788815940095,0.3937322929558605,-0.14445310808685582,0.001537164702395684,0.5164299238420278,1.0222645998514908,0.7602824013383189,1.5794717175274886,-0.33343552863307785,-0.01926704960112091,0.20866925843125922,1.1224519125778383,0.6995066854647584,-0.33343552863307785,1.618928329270631,1.6780316249499048,-0.6946624831235061,0.6386074394794051,-0.06092655176681376,1.1624404216515005,0.5164299238420278,1.0222645998514908,0.3937322929558605,0.5368284738518867,0.10530734984835549,1.1224519125778383,0.2499026019446144,0.5368284738518867,2.399390495804993,-0.8235988933073602,0.4346904255440359,1.0222645998514908,-0.4602671791946553,0.7805138743060999,1.2422720024056197,0.27049579609526114,-0.29131079005371857,0.49601692885848886,2.0891147678360613,-0.35452613486786577,0.352714297145243,-0.08178207009671594,0.08458639893558295,0.7400374285311478,1.8939254041622147,0.7602824013383189,-0.417912582552414,-0.10265492269446272,-0.18632207833549766,-0.16537868346442086,0.921762273203752,0.5368284738518867,-0.16537868346442086,0.18802891238331532,0.6589210414523182,0.06384901323418327,-0.4390800866390325,-0.04008825025596049,-0.2702763842063141,0.8814712891547717,0.04309508514240472,0.001537164702395684,0.2910734677256283,0.6182798801100748,0.08458639893558295,0.5368284738518867,0.9620015287859891,-1.3701528148541127,0.352714297145243,1.1824164060489466,0.022324505727692668,1.202380291141655,-0.20728341801373437,0.37323082292864296,1.142452277500605,1.0824142734467934,1.0824142734467934,0.9821019275934442,-0.08178207009671594,-0.5027007309924332,1.321912831571934,-0.14445310808685582,-0.14445310808685582,0.022324505727692668,0.33218262437609547,0.18802891238331532,1.1224519125778383,-0.16537868346442086,-4.163068613869287,0.06384901323418327,-0.29131079005371857,0.4346904255440359,0.5368284738518867,0.597938284242163,-0.35452613486786577 | 2,945 |
Nucleotide-binding alpha-beta plait domain superfamily [IPR012677] | 48 | 119 | 3.900058 | 0.000096 | P31943,Q15056,Q8WUA2,Q15233,O14979,P55795,P98175,Q9GZT3,Q86U42,Q16629,P52272,P07910,P19338,Q08170,O43390,Q96E39,Q92804,P43243,P51991,Q8N684,Q96PK6,P98179,Q9Y5S9,P31942,P62995,Q9P2K5,Q07955,Q13242,Q9H501,Q96T58,Q99729,P23246,Q14103,O60506,Q14011,Q13595,P52597,Q01844,P22626,Q8NFH5,Q9BWF3,P38159,P09651,Q8WVV9,P35637,P23588,Q9Y4C8,O75494 | Sequence | InterPro Superfamily | interpro_homologous_superfamily | 375,255,521,517,132,514,515,146,276,407,535,401,532,163,169,173,180,424,182,444,188,61,465,195,197,199,324,77,340,208,209,333,335,215,93,346,225,226,224,501,239,109,359,242,115,120,527,127 | 1046,132,969,2121,169,1382,215,127,1162,2428,1527,1340,401,930,1092,863,359,660,1670,1345,532,224,333,120,2092,1392,935,195,375,2096,115,109,2559,424,1480,182,535,225,663,514,1141,1398,197,871,515,61,2642,622,226,2304,324,163,835,2018,563,77,2139,717,1550,1172,346,93,335,2245,1601,1764,1725,255,517,1726,988,407,1212,2275,1446,1972,276,1267,1366,805,444,501,1185,1499,521,242,2827,722,1878,180,1324,173,1834,694,188,208,209,239,1561,2359,146,340,1702,1703,1331,755,1002,199,1742,1891,2933,1236,788,2046,732,634,527,465,2160 | 0.14670037120281113,1.4212012137589964,0.18802891238331532,-0.35452613486786577,1.202380291141655,-0.01926704960112091,1.0423270044122548,1.4806368149043725,0.08458639893558295,-0.5665017880289501,-0.08178207009671594,0.001537164702395684,0.6589210414523182,0.20866925843125922,0.12601197226717611,0.2499026019446144,0.7197788815940095,0.3937322929558605,-0.14445310808685582,0.001537164702395684,0.5164299238420278,1.0222645998514908,0.7602824013383189,1.5794717175274886,-0.33343552863307785,-0.01926704960112091,0.20866925843125922,1.1224519125778383,0.6995066854647584,-0.33343552863307785,1.618928329270631,1.6780316249499048,-0.6946624831235061,0.6386074394794051,-0.06092655176681376,1.1624404216515005,0.5164299238420278,1.0222645998514908,0.3937322929558605,0.5368284738518867,0.10530734984835549,-0.01926704960112091,1.1224519125778383,0.2499026019446144,0.5368284738518867,2.399390495804993,-0.8235988933073602,0.4346904255440359,1.0222645998514908,-0.4602671791946553,0.7805138743060999,1.2422720024056197,0.27049579609526114,-0.29131079005371857,0.49601692885848886,2.0891147678360613,-0.35452613486786577,0.352714297145243,-0.08178207009671594,0.08458639893558295,0.7400374285311478,1.8939254041622147,0.7602824013383189,-0.417912582552414,-0.10265492269446272,-0.18632207833549766,-0.16537868346442086,0.921762273203752,0.5368284738518867,-0.16537868346442086,0.18802891238331532,0.6589210414523182,0.06384901323418327,-0.4390800866390325,-0.04008825025596049,-0.2702763842063141,0.8814712891547717,0.04309508514240472,0.001537164702395684,0.2910734677256283,0.6182798801100748,0.5572126623575777,0.08458639893558295,-0.06092655176681376,0.5368284738518867,0.9620015287859891,-1.3701528148541127,0.352714297145243,-0.22826282947820883,1.1824164060489466,0.022324505727692668,1.202380291141655,-0.20728341801373437,0.37323082292864296,1.142452277500605,1.0824142734467934,1.0824142734467934,0.9821019275934442,-0.08178207009671594,-0.5027007309924332,1.321912831571934,0.7602824013383189,-0.14445310808685582,-0.14445310808685582,0.022324505727692668,0.33218262437609547,0.18802891238331532,1.1224519125778383,-0.16537868346442086,-0.22826282947820883,-4.163068613869287,0.06384901323418327,0.3116357123478239,-0.29131079005371857,0.352714297145243,0.4346904255440359,0.5368284738518867,0.597938284242163,-0.35452613486786577 | 2,945 |
RNA-binding domain superfamily [IPR035979] | 48 | 120 | 3.842299 | 0.000122 | P31943,Q15056,Q8WUA2,Q15233,O14979,P55795,P98175,Q9GZT3,Q86U42,Q16629,P52272,P07910,P19338,Q08170,O43390,Q96E39,Q92804,P43243,P51991,Q8N684,Q96PK6,P98179,Q71RC2,Q9Y5S9,P31942,P62995,Q9P2K5,Q07955,Q13242,Q96T58,Q99729,P23246,Q14103,O60506,Q14011,Q13595,P52597,Q01844,P22626,Q8NFH5,Q9BWF3,P38159,P09651,Q8WVV9,P35637,P23588,Q9Y4C8,O75494 | Sequence | InterPro Superfamily | interpro_homologous_superfamily | 375,255,521,517,132,514,515,146,276,407,535,401,532,163,169,173,180,424,182,444,188,61,457,465,195,197,199,324,77,208,209,333,335,215,93,346,225,226,224,501,239,109,359,242,115,120,527,127 | 1046,132,969,2121,169,1382,215,127,1162,2428,1527,1340,401,930,1092,863,359,660,1670,1345,532,224,333,120,2092,1392,935,195,375,2096,115,109,2559,424,1480,182,535,225,663,514,1141,197,871,515,61,2642,622,226,2304,324,163,835,2018,563,77,2139,717,1550,1172,346,93,335,2245,1601,1764,1725,255,517,1726,988,407,1212,2275,1446,457,1972,276,1267,1366,805,444,501,1185,521,242,2827,722,1878,180,1324,173,1834,694,188,208,209,1651,239,1652,1561,2359,146,1930,1702,1703,1331,755,1002,199,1742,1891,2933,1236,788,2046,732,634,527,465,2160 | 0.14670037120281113,1.4212012137589964,0.18802891238331532,-0.35452613486786577,1.202380291141655,-0.01926704960112091,1.0423270044122548,1.4806368149043725,0.08458639893558295,-0.5665017880289501,-0.08178207009671594,0.001537164702395684,0.6589210414523182,0.20866925843125922,0.12601197226717611,0.2499026019446144,0.7197788815940095,0.3937322929558605,-0.14445310808685582,0.001537164702395684,0.5164299238420278,1.0222645998514908,0.7602824013383189,1.5794717175274886,-0.33343552863307785,-0.01926704960112091,0.20866925843125922,1.1224519125778383,0.6995066854647584,-0.33343552863307785,1.618928329270631,1.6780316249499048,-0.6946624831235061,0.6386074394794051,-0.06092655176681376,1.1624404216515005,0.5164299238420278,1.0222645998514908,0.3937322929558605,0.5368284738518867,0.10530734984835549,1.1224519125778383,0.2499026019446144,0.5368284738518867,2.399390495804993,-0.8235988933073602,0.4346904255440359,1.0222645998514908,-0.4602671791946553,0.7805138743060999,1.2422720024056197,0.27049579609526114,-0.29131079005371857,0.49601692885848886,2.0891147678360613,-0.35452613486786577,0.352714297145243,-0.08178207009671594,0.08458639893558295,0.7400374285311478,1.8939254041622147,0.7602824013383189,-0.417912582552414,-0.10265492269446272,-0.18632207833549766,-0.16537868346442086,0.921762273203752,0.5368284738518867,-0.16537868346442086,0.18802891238331532,0.6589210414523182,0.06384901323418327,-0.4390800866390325,-0.04008825025596049,0.597938284242163,-0.2702763842063141,0.8814712891547717,0.04309508514240472,0.001537164702395684,0.2910734677256283,0.6182798801100748,0.5572126623575777,0.08458639893558295,0.5368284738518867,0.9620015287859891,-1.3701528148541127,0.352714297145243,-0.22826282947820883,1.1824164060489466,0.022324505727692668,1.202380291141655,-0.20728341801373437,0.37323082292864296,1.142452277500605,1.0824142734467934,1.0824142734467934,-0.12354522852272666,0.9821019275934442,-0.12354522852272666,-0.08178207009671594,-0.5027007309924332,1.321912831571934,-0.2492604414061187,-0.14445310808685582,-0.14445310808685582,0.022324505727692668,0.33218262437609547,0.18802891238331532,1.1224519125778383,-0.16537868346442086,-0.22826282947820883,-4.163068613869287,0.06384901323418327,0.3116357123478239,-0.29131079005371857,0.352714297145243,0.4346904255440359,0.5368284738518867,0.597938284242163,-0.35452613486786577 | 2,945 |
Oxidoreductase | 22 | 109 | 3.788282 | 0.000152 | P00374,P03886,Q15392,P11310,O95881,Q14739,Q9BY49,P00403,Q8N4Q0,O94788,P30837,P13995,P05091,Q9H845,Q8N8N7,O95831,Q16850,Q8N0U8,Q13423,Q96CU9,O15260,P21912 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 1,2,5,11,149,29,37,166,44,49,55,185,67,70,75,89,101,110,112,113,114,119 | 2257,1663,114,2922,1791,2553,1946,1468,1577,373,825,1903,2619,49,1388,89,149,2574,2053,1,1529,166,2,2690,2228,67,2342,2556,826,1015,11,1852,2576,2234,185,1053,2203,1671,2126,1797,794,119,2091,2431,2093,2129,2373,2756,685,55,1750,555,2208,210,2002,1752,2005,2486,557,2635,1099,1137,2580,1592,2269,1909,1355,1910,1819,907,404,583,112,1313,29,2873,602,5,2847,2108,1319,1870,101,1967,2912,1031,2546,2330,110,44,75,646,2466,1732,113,586,2074,1276,37,813,70,2570,1459,1280,2940,2628,2197,2829,299 | -0.4390800866390325,-0.14445310808685582,1.618928329270631,-3.0625718756916878,-0.20728341801373437,-0.6946624831235061,-0.2702763842063141,-0.06092655176681376,-0.10265492269446272,0.6995066854647584,0.27049579609526114,-0.2492604414061187,-0.7805314905603624,2.6113277676568396,-0.01926704960112091,1.9330438639514882,1.2821160279306807,-0.7160969742146781,-0.31236379292464844,7.448017023011698,-0.08178207009671594,1.2223321368163933,7.077162194942315,-0.9100071940702691,-0.417912582552414,2.341397984173776,-0.5027007309924332,-0.6946624831235061,0.27049579609526114,0.1673726504047501,4.9168542761704375,-0.22826282947820883,-0.7160969742146781,-0.417912582552414,1.142452277500605,0.14670037120281113,-0.3967645192768137,-0.14445310808685582,-0.35452613486786577,-0.20728341801373437,0.2910734677256283,1.5794717175274886,-0.33343552863307785,-0.5665017880289501,-0.33343552863307785,-0.35452613486786577,-0.5239474963343811,-1.105820052560868,0.37323082292864296,2.4573001148610345,-0.18632207833549766,0.49601692885848886,-0.3967645192768137,1.062376874281129,-0.29131079005371857,-0.18632207833549766,-0.29131079005371857,-0.609138164405286,0.49601692885848886,-0.8020539598800626,0.12601197226717611,0.10530734984835549,-0.7160969742146781,-0.10265492269446272,-0.4390800866390325,-0.2492604414061187,0.001537164702395684,-0.2492604414061187,-0.20728341801373437,0.2292937886448734,0.6589210414523182,0.4755894045159319,1.6583413438014383,0.022324505727692668,3.655794126757704,-1.751769488181549,0.4551472654983724,5.735788324107087,-1.5262302338877283,-0.33343552863307785,0.022324505727692668,-0.22826282947820883,1.7763226939226555,-0.2702763842063141,-2.5624413965643553,0.1673726504047501,-0.6732495316326513,-0.4814740099977851,1.6780316249499048,2.860424771989179,2.1085789946182025,0.4142187974298949,-0.587809634186986,-0.16537868346442086,1.6386402615157454,0.4755894045159319,-0.31236379292464844,0.04309508514240472,3.2408955872793364,0.2910734677256283,2.2057541946060866,-0.6946624831235061,-0.04008825025596049,0.04309508514240472,-5.9391553365988985,-0.7805314905603624,-0.37563575123099097,-1.3701528148541127,0.8411280257469278 | 2,945 |
Nuclear outer membrane endoplasmic reticulum membrane network | 48 | 295 | 3.743485 | 0.000181 | P07099,Q15392,O60725,Q99720,P37268,Q9UBF8,Q9NZ08,Q969N2,P62942,Q6NUQ1,Q14739,Q8N511,Q9H3N1,P35613,Q9BUN8,Q9Y282,Q5JRA6,Q86XL3,O43852,P04439,Q9BQE5,Q92643,P04843,P24390,P43307,Q96G23,O00264,Q8NHP6,Q8NFQ8,O76024,O75844,Q86UE4,Q6UWP7,Q8TD16,P48449,P30519,Q16850,P49257,Q07065,P35610,Q8N0U8,Q8TCJ2,O15027,O15260,Q9BS26,Q9H2M9,Q9BZF1,Q12907 | Localization | GO Cellular component | msigdb_gocc | 4,5,6,8,12,16,22,152,25,28,29,30,159,161,38,41,172,46,48,175,51,52,184,64,68,72,192,73,74,76,80,81,211,87,91,96,101,231,233,107,110,111,236,114,245,246,118,123 | 300,2784,1193,192,446,678,819,1427,2926,467,1664,1621,236,114,1788,1286,509,2164,2426,510,2772,48,1794,2313,6,1049,2890,1288,1124,1161,2088,2855,80,825,1949,76,859,417,1008,553,1196,762,2856,1164,899,1580,2786,1848,738,1905,2719,739,2773,175,184,791,929,2403,4,659,1472,2259,419,468,402,683,1296,1297,1347,2127,64,1131,2206,707,423,2129,740,96,2056,2207,2095,1393,107,161,12,1019,1859,1056,68,1394,979,91,2436,1634,1811,231,2179,903,1590,315,1395,939,597,868,2009,1303,2347,2438,769,1679,1816,2210,2728,2103,2775,1862,323,1258,2011,2135,1024,2581,942,2488,1207,25,1864,1760,2408,1209,404,451,2776,233,2460,908,2065,642,123,2888,2737,473,2710,873,2931,1866,1313,29,1867,1495,2544,2837,1316,951,2923,5,1148,1683,2653,2847,2582,2935,101,2677,1728,2835,275,2526,172,1685,1496,1072,28,953,2788,1364,2111,211,585,1556,2143,520,81,498,46,2704,2679,957,110,287,460,2744,30,1183,745,989,337,2145,74,2769,73,1222,2875,2466,111,806,2739,87,353,522,625,1411,52,1879,152,381,1452,1228,1880,2716,1229,540,72,2732,586,1372,1153,1736,394,2513,1272,886,2586,887,607,8,888,2894,51,245,1839,649,723,38,2853,2879,2418,118,725,369,650,246,159,2587,2696,1740,2822,2473,2193,253,628,753,2919,2550,1932,2836,2613,1082,1280,22,1890,1422,341,610,16,2628,270,2154,2199,789,758,1743,41,1466,2854,2396,2450,2084,2647,482,2881,2863,371,590,1519 | 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| 2,945 |
Endoplasmic reticulum lumen | 27 | 55 | 3.601964 | 0.000316 | Q32P28,Q15293,Q9NYU2,P14314,O75718,Q96AY3,Q9NZ08,Q9Y4L1,O95881,Q14257,Q7Z4H8,P27824,Q5JRA6,O43852,P07237,P13674,Q9NWM8,Q9UNW1,O76024,Q8IXB1,P14625,Q9Y680,O15460,P13667,Q07065,Q9BS26,Q13217 | Localization | GO Cellular component | msigdb_gocc | 136,139,143,390,388,19,22,291,149,26,296,423,172,48,418,176,59,342,76,206,468,98,100,344,233,245,241 | 100,1159,48,388,76,149,418,2602,2575,1851,344,176,390,468,1854,2592,2177,707,423,2094,534,740,904,2319,1820,233,1723,241,26,688,951,139,136,172,2788,296,498,206,646,2465,746,1732,1502,19,586,245,2712,2472,1417,59,143,22,342,291,98 | 1.7763226939226555,0.08458639893558295,2.6113277676568396,0.6792207642978566,2.0891147678360613,1.2821160279306807,0.6386074394794051,-0.7590312945413134,-0.7160969742146781,-0.22826282947820883,0.7400374285311478,1.1824164060489466,0.6792207642978566,0.5775825719273033,-0.22826282947820883,-0.7375531840373677,-0.37563575123099097,0.352714297145243,0.6386074394794051,-0.33343552863307785,0.5164299238420278,0.33218262437609547,0.2292937886448734,-0.4814740099977851,-0.20728341801373437,1.0021895959906988,-0.16537868346442086,0.9620015287859891,3.693333183718309,0.37323082292864296,0.20866925843125922,1.3616628687817531,1.4013665868313239,1.202380291141655,-1.1935008981215134,0.8411280257469278,0.5572126623575777,1.0824142734467934,0.4142187974298949,-0.587809634186986,0.33218262437609547,-0.16537868346442086,-0.06092655176681376,4.34572728753516,0.4755894045159319,0.9620015287859891,-0.9533513246189271,-0.587809634186986,-0.01926704960112091,2.438006058944413,1.3417936678371196,3.824492664661767,0.7602824013383189,0.8613062272321225,1.835170758534991 | 2,945 |
Oxidoreductase | 31 | 156 | 3.540023 | 0.0004 | P00374,Q15392,Q32P28,Q16836,P11310,P48735,Q9UHG3,Q8NB78,P78417,O95881,Q14739,Q9BY49,Q8N4Q0,O94788,P13674,P30837,Q99536,P13995,P05091,Q9H845,Q9NWT6,Q8N8N7,Q8IXB1,P32119,O95831,P30519,O15460,Q16850,Q8N0U8,Q96CU9,P21912 | Functions | Protein Atlas Molecular function | protein_atlas_molecular_function | 1,5,136,138,11,145,20,21,150,149,29,37,44,49,176,55,189,185,67,70,204,75,206,210,89,96,100,101,110,113,119 | 311,819,467,100,1791,2553,2650,321,1577,373,705,825,595,49,89,738,149,2574,2053,1,2719,1529,2773,2690,2228,67,2342,1849,2556,2259,826,932,11,1852,2576,1473,2815,176,185,2203,2126,2910,1168,402,2204,119,2237,2205,2091,2431,2093,2373,2756,1954,685,96,55,1750,555,2208,210,2058,271,2002,2005,2486,1808,557,2404,2749,145,2635,1716,1099,1137,2376,2580,868,1592,1593,1909,1355,1910,870,150,1819,2439,907,404,714,642,583,1310,1313,29,2873,602,5,2653,2847,2108,138,101,136,1967,1728,2781,803,1920,1496,1072,1406,442,1554,2912,1031,1180,2306,206,110,44,75,21,2819,958,2907,2466,1732,1604,1322,2469,113,586,2740,750,433,189,2074,888,2548,1276,37,2861,70,2570,2797,204,2286,1280,1614,2628,2197,1933,20,223,2854 | 0.8007319209650764,0.27049579609526114,0.5775825719273033,1.7763226939226555,-0.20728341801373437,-0.6946624831235061,-0.845166484742484,0.7805138743060999,-0.10265492269446272,0.6995066854647584,0.352714297145243,0.27049579609526114,0.4551472654983724,2.6113277676568396,1.9330438639514882,0.33218262437609547,1.2821160279306807,-0.7160969742146781,-0.31236379292464844,7.448017023011698,-0.9967910215997426,-0.08178207009671594,-1.1496084842326584,-0.9100071940702691,-0.417912582552414,2.341397984173776,-0.5027007309924332,-0.22826282947820883,-0.6946624831235061,-0.4390800866390325,0.27049579609526114,0.20866925843125922,4.9168542761704375,-0.22826282947820883,-0.7160969742146781,-0.06092655176681376,-1.3037005802478918,1.1824164060489466,1.142452277500605,-0.3967645192768137,-0.35452613486786577,-2.468271461003765,0.08458639893558295,0.6589210414523182,-0.3967645192768137,1.5794717175274886,-0.417912582552414,-0.3967645192768137,-0.33343552863307785,-0.5665017880289501,-0.33343552863307785,-0.5239474963343811,-1.105820052560868,-0.2702763842063141,0.37323082292864296,1.8547659602664823,2.4573001148610345,-0.18632207833549766,0.49601692885848886,-0.3967645192768137,1.062376874281129,-0.31236379292464844,0.8814712891547717,-0.29131079005371857,-0.29131079005371857,-0.609138164405286,-0.20728341801373437,0.49601692885848886,-0.5452144624387532,-1.0839642060391366,1.321912831571934,-0.8020539598800626,-0.16537868346442086,0.12601197226717611,0.10530734984835549,-0.5239474963343811,-0.7160969742146781,0.2499026019446144,-0.10265492269446272,-0.10265492269446272,-0.2492604414061187,0.001537164702395684,-0.2492604414061187,0.2499026019446144,1.2821160279306807,-0.20728341801373437,-0.5665017880289501,0.2292937886448734,0.6589210414523182,0.352714297145243,0.4142187974298949,0.4755894045159319,0.022324505727692668,0.022324505727692668,3.655794126757704,-1.751769488181549,0.4551472654983724,5.735788324107087,-0.845166484742484,-1.5262302338877283,-0.33343552863307785,1.3815204900608,1.7763226939226555,1.4013665868313239,-0.2702763842063141,-0.16537868346442086,-1.1715415663081576,0.2910734677256283,-0.2492604414061187,-0.06092655176681376,0.14670037120281113,-0.01926704960112091,0.6182798801100748,-0.08178207009671594,-2.5624413965643553,0.1673726504047501,0.08458639893558295,-0.4602671791946553,1.0824142734467934,1.6780316249499048,2.860424771989179,2.1085789946182025,4.01126221185754,-1.3258230481672575,0.20866925843125922,-2.2810507976197463,-0.587809634186986,-0.16537868346442086,-0.10265492269446272,0.022324505727692668,-0.587809634186986,1.6386402615157454,0.4755894045159319,-1.0403280423845351,0.33218262437609547,0.6386074394794051,1.142452277500605,-0.31236379292464844,0.2499026019446144,-0.6732495316326513,0.04309508514240472,3.2408955872793364,-1.6386272017792467,2.2057541946060866,-0.6946624831235061,-1.2154867397644784,1.1024392652871489,-0.4390800866390325,0.04309508514240472,-0.10265492269446272,-0.7805314905603624,-0.37563575123099097,-0.2492604414061187,4.1043876915125255,1.0423270044122548,-1.5710975994835399 | 2,945 |
Negative regulation of mrna metabolic process | 25 | 44 | 3.524286 | 0.000425 | P67809,P61978,Q5VTR2,P98175,Q16629,P07910,Q08170,P11940,Q6PD62,Q6PJT7,Q07021,Q92804,Q13151,Q13247,Q13242,Q99729,Q14103,O60506,Q14011,P22626,P38159,P35637,O75150,Q06787,O75494 | Processes and pathways | GO Biological process | msigdb_gobp | 129,134,644,515,407,401,163,660,565,428,178,180,563,717,77,209,335,215,93,224,109,115,484,254,127 | 1193,968,1786,215,484,127,1384,401,660,1345,224,2092,1392,115,109,980,134,129,515,1722,254,178,163,1492,1100,2018,563,77,717,93,335,988,1027,407,644,565,428,1030,1878,180,209,812,1002,733 | 0.06384901323418327,0.18802891238331532,-0.20728341801373437,1.0423270044122548,0.5572126623575777,1.4806368149043725,-0.01926704960112091,0.6589210414523182,0.3937322929558605,0.001537164702395684,1.0222645998514908,-0.33343552863307785,-0.01926704960112091,1.618928329270631,1.6780316249499048,0.18802891238331532,1.4212012137589964,1.4410244250244986,0.5368284738518867,-0.16537868346442086,0.921762273203752,1.1824164060489466,1.2422720024056197,-0.06092655176681376,0.12601197226717611,-0.29131079005371857,0.49601692885848886,2.0891147678360613,0.352714297145243,1.8939254041622147,0.7602824013383189,0.18802891238331532,0.1673726504047501,0.6589210414523182,0.4142187974298949,0.49601692885848886,0.6386074394794051,0.1673726504047501,-0.22826282947820883,1.1824164060489466,1.0824142734467934,0.2910734677256283,0.18802891238331532,0.352714297145243 | 2,945 |
Fatigue | 15 | 72 | 3.463715 | 0.000533 | Q15165,O15460,Q4J6C6,Q70HW3,P11310,Q07021,Q92804,Q13423,P35637,Q04656,P21912,Q9NZ08,Q969N2,Q6UN15,Q14739 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 0,100,137,10,11,178,180,112,115,148,119,22,152,125,29 | 1991,678,100,174,1164,1011,739,2746,1668,2767,1013,763,1245,2932,2482,1014,359,530,11,2456,706,827,119,2127,1628,707,1750,2001,115,1673,1353,1955,1134,2486,937,424,902,1716,2869,711,1756,2270,1679,2062,440,906,2017,148,178,1443,2018,112,718,29,1314,2638,0,2643,137,2723,2110,125,10,2564,180,152,755,22,2599,700,482,1520 | -0.29131079005371857,0.37323082292864296,1.7763226939226555,1.1824164060489466,0.08458639893558295,0.1673726504047501,0.33218262437609547,-1.0839642060391366,-0.14445310808685582,-1.1277013965550577,0.1673726504047501,0.3116357123478239,0.04309508514240472,-3.890742390654541,-0.609138164405286,0.1673726504047501,0.7197788815940095,0.5164299238420278,4.9168542761704375,-0.587809634186986,0.352714297145243,0.27049579609526114,1.5794717175274886,-0.35452613486786577,-0.12354522852272666,0.352714297145243,-0.18632207833549766,-0.29131079005371857,1.618928329270631,-0.14445310808685582,0.001537164702395684,-0.2702763842063141,0.10530734984835549,-0.609138164405286,0.20866925843125922,0.6386074394794051,0.2292937886448734,-0.16537868346442086,-1.7064250666788545,0.352714297145243,-0.18632207833549766,-0.4390800866390325,-0.14445310808685582,-0.31236379292464844,0.6182798801100748,0.2292937886448734,-0.29131079005371857,1.3020203038267055,1.1824164060489466,-0.04008825025596049,-0.29131079005371857,1.6583413438014383,0.352714297145243,3.655794126757704,0.022324505727692668,-0.8020539598800626,7.623940234694683,-0.8235988933073602,1.4013665868313239,-0.9967910215997426,-0.33343552863307785,1.5004260995112062,5.045004847981975,-0.6946624831235061,1.1824164060489466,1.2821160279306807,0.33218262437609547,3.824492664661767,-0.7375531840373677,0.37323082292864296,0.5775825719273033,-0.06092655176681376 | 2,945 |
Mrna binding | 59 | 160 | 3.440145 | 0.000581 | P00374,P67809,P61978,Q9NPI6,Q5VTR2,O60306,P35580,Q07666,Q96I24,P52272,P52756,P07910,P19338,Q08170,P11940,Q04637,P52948,O43390,Q9H2U1,Q07021,Q92804,Q13151,P51991,Q8N684,Q96PK6,P51114,P51116,Q71RC2,Q9Y5S9,Q96PU8,Q9BWU0,Q9BPZ3,P62995,Q9P2K5,Q07955,Q13247,P23396,P12270,O75153,P27797,Q96T58,Q99729,O43432,Q14103,P34896,O60506,Q14011,P22626,Q9Y3B4,Q96MU7,Q9BWF3,P38159,Q96AE4,Q15637,Q01085,Q8WVV9,P35637,O75150,Q06787 | Functions | GO Molecular function | msigdb_gomf | 1,129,134,398,644,636,513,273,410,535,663,401,532,163,660,537,295,169,695,178,180,563,182,444,188,439,686,457,465,330,724,588,197,199,324,717,579,578,78,707,208,209,85,335,708,215,93,224,634,368,239,109,366,363,622,242,115,484,254 | 968,1046,927,1575,169,85,2291,1793,636,215,484,1160,78,1125,2166,1527,1,1668,2631,1012,1340,401,1092,660,578,2055,1670,2316,933,2499,532,1169,2500,224,579,1298,1392,707,935,2096,708,976,513,115,109,2003,2501,1633,2458,743,2267,1480,439,686,982,182,535,663,2102,295,1718,2134,1358,1758,1759,134,1911,2540,2184,1487,197,129,1061,2016,1359,1722,622,537,254,178,273,324,163,1492,714,872,1494,835,1171,1442,2018,563,2139,717,1550,1172,93,335,1551,1444,2022,2140,2247,1869,363,988,1212,644,1030,457,1267,2353,444,1219,2251,1976,1831,242,1878,180,1226,366,1834,1835,410,368,188,330,1186,208,2682,209,588,2771,2034,239,724,1610,1561,1983,1154,695,1156,2474,398,1700,1779,1002,199,1891,2046,1937,1516,1239,1619,634,2200,2117,465,2160 | 0.18802891238331532,0.14670037120281113,0.20866925843125922,-0.10265492269446272,1.202380291141655,1.9525878342172756,-0.4602671791946553,-0.20728341801373437,0.4142187974298949,1.0423270044122548,0.5572126623575777,0.08458639893558295,2.0696407183096763,0.10530734984835549,-0.37563575123099097,-0.08178207009671594,7.448017023011698,-0.14445310808685582,-0.8020539598800626,0.1673726504047501,0.001537164702395684,0.6589210414523182,0.12601197226717611,0.3937322929558605,0.4755894045159319,-0.31236379292464844,-0.14445310808685582,-0.4814740099977851,0.20866925843125922,-0.6304875446399937,0.5164299238420278,0.08458639893558295,-0.6304875446399937,1.0222645998514908,0.4755894045159319,0.022324505727692668,-0.01926704960112091,0.352714297145243,0.20866925843125922,-0.33343552863307785,0.352714297145243,0.18802891238331532,0.5368284738518867,1.618928329270631,1.6780316249499048,-0.29131079005371857,-0.6304875446399937,-0.12354522852272666,-0.587809634186986,0.33218262437609547,-0.4390800866390325,-0.06092655176681376,0.6182798801100748,0.37323082292864296,0.18802891238331532,1.1624404216515005,0.5164299238420278,0.3937322929558605,-0.33343552863307785,0.8411280257469278,-0.16537868346442086,-0.35452613486786577,0.001537164702395684,-0.18632207833549766,-0.18632207833549766,1.4212012137589964,-0.2492604414061187,-0.6732495316326513,-0.37563575123099097,-0.06092655176681376,1.1224519125778383,1.4410244250244986,0.14670037120281113,-0.29131079005371857,0.001537164702395684,-0.16537868346442086,0.4346904255440359,0.5164299238420278,0.921762273203752,1.1824164060489466,0.8814712891547717,0.7805138743060999,1.2422720024056197,-0.06092655176681376,0.352714297145243,0.2499026019446144,-0.06092655176681376,0.27049579609526114,0.08458639893558295,-0.04008825025596049,-0.29131079005371857,0.49601692885848886,-0.35452613486786577,0.352714297145243,-0.08178207009671594,0.08458639893558295,1.8939254041622147,0.7602824013383189,-0.08178207009671594,-0.04008825025596049,-0.29131079005371857,-0.35452613486786577,-0.417912582552414,-0.22826282947820883,0.7197788815940095,0.18802891238331532,0.06384901323418327,0.4142187974298949,0.1673726504047501,0.597938284242163,0.04309508514240472,-0.5027007309924332,0.6182798801100748,0.06384901323418327,-0.417912582552414,-0.2702763842063141,-0.20728341801373437,0.9620015287859891,-0.22826282947820883,1.1824164060489466,0.06384901323418327,0.7197788815940095,-0.20728341801373437,-0.20728341801373437,0.6589210414523182,0.7197788815940095,1.142452277500605,0.7805138743060999,0.08458639893558295,1.0824142734467934,-0.8883704331508439,1.0824142734467934,0.4755894045159319,-1.1277013965550577,-0.29131079005371857,0.9821019275934442,0.352714297145243,-0.10265492269446272,-0.08178207009671594,-0.2702763842063141,0.10530734984835549,0.37323082292864296,0.10530734984835549,-0.587809634186986,0.6792207642978566,-0.14445310808685582,-0.18632207833549766,0.18802891238331532,1.1224519125778383,-0.22826282947820883,-0.29131079005371857,-0.2492604414061187,-0.06092655176681376,0.06384901323418327,-0.10265492269446272,0.4346904255440359,-0.37563575123099097,-0.33343552863307785,0.597938284242163,-0.35452613486786577 | 2,945 |
Mitotic g1 phase and g1 s transition | 12 | 74 | 3.337899 | 0.000844 | Q14566,P00374,P25787,Q07864,P60900,P28072,P31751,P20618,Q9Y619,Q13547,Q9NRF9,P28070 | Processes and pathways | Reactome Pathways | msigdb_reactome | 227,1,3,162,196,69,262,261,50,54,247,31 | 550,2398,2163,1523,1337,2258,1622,1,2537,2631,929,1624,2232,2202,1295,1434,975,1672,261,795,422,1249,3,1533,2483,1799,1631,31,69,829,617,294,555,262,1251,1713,1352,438,2318,937,1809,2578,1589,938,2505,469,981,561,1306,196,580,1863,1638,1595,800,2523,2244,162,1210,2216,1311,54,2020,227,1265,2279,504,1114,247,1191,1237,1568,2480,50 | 0.49601692885848886,-0.5452144624387532,-0.37563575123099097,-0.08178207009671594,0.001537164702395684,-0.4390800866390325,-0.12354522852272666,7.448017023011698,-0.6732495316326513,-0.8020539598800626,0.20866925843125922,-0.12354522852272666,-0.417912582552414,-0.3967645192768137,0.022324505727692668,-0.04008825025596049,0.18802891238331532,-0.14445310808685582,0.9016232814114782,0.2910734677256283,0.6386074394794051,0.04309508514240472,6.86435802761024,-0.08178207009671594,-0.609138164405286,-0.20728341801373437,-0.12354522852272666,3.5053441140537633,2.2639439873853995,0.27049579609526114,0.4346904255440359,0.8411280257469278,0.49601692885848886,0.9016232814114782,0.04309508514240472,-0.16537868346442086,0.001537164702395684,0.6182798801100748,-0.4814740099977851,0.20866925843125922,-0.20728341801373437,-0.7160969742146781,-0.10265492269446272,0.20866925843125922,-0.6304875446399937,0.5775825719273033,0.18802891238331532,0.49601692885848886,0.022324505727692668,1.1224519125778383,0.4755894045159319,-0.22826282947820883,-0.12354522852272666,-0.10265492269446272,0.2910734677256283,-0.6518579433658428,-0.417912582552414,1.2422720024056197,0.06384901323418327,-0.3967645192768137,0.022324505727692668,2.4765850676126675,-0.29131079005371857,1.0222645998514908,0.04309508514240472,-0.4390800866390325,0.5572126623575777,0.12601197226717611,0.9620015287859891,0.08458639893558295,0.06384901323418327,-0.08178207009671594,-0.587809634186986,2.592105567404909 | 2,945 |
Oxidoreductase activity | 39 | 217 | 3.300668 | 0.000965 | P00374,P03886,Q15392,Q32P28,Q16836,P11310,P48735,Q9UHG3,Q8NB78,P78417,O95881,Q14739,Q9H3N1,Q9BY49,P00403,Q8N4Q0,O94788,P13674,P30837,Q99536,P13995,O96000,O00330,P05091,Q9H845,Q9NWT6,Q8N8N7,Q8IXB1,P61457,P32119,O95831,O43396,P30519,O15460,Q16850,Q8N0U8,Q13423,Q96CU9,P21912 | Functions | GO Molecular function | msigdb_gomf | 1,2,5,136,138,11,145,20,21,150,149,29,159,37,166,44,49,176,55,189,185,63,193,67,70,204,75,206,86,210,89,90,96,100,101,110,112,113,119 | 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| 2,945 |
Disorders of transmembrane transporters | 23 | 73 | 3.217298 | 0.001294 | P25787,Q9BTX1,P20618,P08195,P28070,P35613,Q9BUN8,P52948,P51665,O00231,Q8NFH4,P60900,Q8N1F7,P28072,Q5SRE5,P61289,O00400,Q8TEM1,P49721,Q99436,Q9GZP9,Q8NFH5,O75694 | Processes and pathways | Reactome Pathways | msigdb_reactome | 3,259,261,144,31,161,38,295,561,550,320,196,327,69,325,580,446,353,469,504,369,501,485 | 550,2398,446,2163,1523,1337,485,1622,1008,144,578,1672,2429,261,1249,3,1533,2483,1631,31,69,829,161,1536,2318,1478,1809,2578,2505,469,2101,1590,561,295,1140,1306,1679,712,196,580,1863,1638,1595,2137,2244,1913,1210,2750,1265,325,1364,840,327,1450,320,501,353,959,2279,1689,919,504,1114,1034,259,38,1609,1415,369,2361,1423,1237,1568 | 0.49601692885848886,-0.5452144624387532,0.597938284242163,-0.37563575123099097,-0.08178207009671594,0.001537164702395684,0.5572126623575777,-0.12354522852272666,0.1673726504047501,1.321912831571934,0.4755894045159319,-0.14445310808685582,-0.5665017880289501,0.9016232814114782,0.04309508514240472,6.86435802761024,-0.08178207009671594,-0.609138164405286,-0.12354522852272666,3.5053441140537633,2.2639439873853995,0.27049579609526114,1.2422720024056197,-0.08178207009671594,-0.4814740099977851,-0.06092655176681376,-0.20728341801373437,-0.7160969742146781,-0.6304875446399937,0.5775825719273033,-0.33343552863307785,-0.10265492269446272,0.49601692885848886,0.8411280257469278,0.10530734984835549,0.022324505727692668,-0.14445310808685582,0.352714297145243,1.1224519125778383,0.4755894045159319,-0.22826282947820883,-0.12354522852272666,-0.10265492269446272,-0.35452613486786577,-0.417912582552414,-0.2492604414061187,0.06384901323418327,-1.0839642060391366,0.04309508514240472,0.7805138743060999,0.001537164702395684,0.27049579609526114,0.7805138743060999,-0.04008825025596049,0.8007319209650764,0.5572126623575777,0.7400374285311478,0.20866925843125922,-0.4390800866390325,-0.14445310808685582,0.2292937886448734,0.5572126623575777,0.12601197226717611,0.1673726504047501,0.921762273203752,3.1270939109566753,-0.10265492269446272,-0.01926704960112091,0.7197788815940095,-0.5027007309924332,-0.01926704960112091,0.06384901323418327,-0.08178207009671594 | 2,945 |
Oxidoreductase activity acting on the ch ch group of donors | 7 | 28 | 3.193328 | 0.001406 | Q9BY49,Q15392,Q9H845,P11310,Q8N4Q0,Q8N8N7,Q14739 | Functions | GO Molecular function | msigdb_gomf | 37,5,70,11,44,75,29 | 2601,11,1168,119,2431,2756,1750,2002,2404,1716,1137,1355,29,2873,602,5,1072,1031,1179,44,75,1322,37,813,70,2286,1280,2628 | -0.7590312945413134,4.9168542761704375,0.08458639893558295,1.5794717175274886,-0.5665017880289501,-1.105820052560868,-0.18632207833549766,-0.29131079005371857,-0.5452144624387532,-0.16537868346442086,0.10530734984835549,0.001537164702395684,3.655794126757704,-1.751769488181549,0.4551472654983724,5.735788324107087,0.14670037120281113,0.1673726504047501,0.08458639893558295,2.860424771989179,2.1085789946182025,0.022324505727692668,3.2408955872793364,0.2910734677256283,2.2057541946060866,-0.4390800866390325,0.04309508514240472,-0.7805314905603624 | 2,945 |
Negative regulation of nucleobase containing compound metabolic process | 87 | 255 | 3.168272 | 0.001533 | Q15233,Q03164,P98175,Q8TAQ2,Q9UPY3,Q9UNS1,Q8NB78,P53999,Q6PD62,Q13151,Q13547,O95817,P46934,O76024,P23396,Q13242,P12270,O75844,Q86UE4,Q96TA1,Q8IWS0,O60934,Q9UBK9,Q14011,P83916,P38159,P35637,Q9UIV1,O75494,Q96IZ0,P67809,P61978,Q5VTR2,O60504,Q9GZT3,Q96KQ7,Q8TDD1,O95251,Q5UIP0,Q06330,Q08170,P11940,Q92878,Q01105,Q9H2U1,Q07021,Q92804,P17096,O00330,Q8WXF1,Q13247,Q9NWT6,P49593,Q9Y2W1,Q96T58,Q99729,O60506,P22626,P42224,Q06787,Q969G3,Q9UMX1,Q9HCD5,Q07666,Q8N163,Q13951,Q9NS86,Q9NYF8,P80723,P23246,Q14103,P12956,P09651,Q15637,Q08J23,Q16629,P07910,Q8NEY8,Q6PJT7,P16220,Q86YP4,Q5VUA4,Q9H814,Q96FV9,P78318,O75150,Q13330 | Processes and pathways | GO Biological process | msigdb_gobp | 517,13,515,539,548,547,21,536,565,563,54,554,558,76,579,77,578,80,81,88,605,594,95,93,600,109,115,117,127,128,129,134,644,637,146,674,671,155,667,664,163,660,692,170,695,178,180,684,193,722,717,204,202,733,208,209,215,224,238,254,257,260,269,273,277,283,305,306,301,333,335,343,359,363,392,407,401,431,428,437,459,456,478,476,471,484,493 | 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| 2,945 |
Regulation of rna splicing | 30 | 78 | 3.131052 | 0.001742 | P31943,P61978,Q07666,Q16629,Q08170,P52948,Q96E39,Q07021,P51114,P98179,Q96PU8,Q96QD8,P31942,P62995,Q5BKZ1,Q07955,Q13242,Q14011,Q13595,P52597,P22626,Q96MU7,Q9BWF3,P38159,P09651,Q15637,Q8WVV9,P35637,Q06787,O75494 | Processes and pathways | GO Biological process | msigdb_gobp | 375,134,273,407,163,295,173,178,439,61,330,66,195,197,198,324,77,93,346,225,224,368,239,109,359,363,242,115,254,127 | 1786,682,1901,127,1092,359,1294,1670,933,1054,532,224,2344,2092,1392,2373,935,195,375,115,109,981,1480,439,686,225,663,295,514,134,2184,197,2878,871,515,61,1722,254,178,273,324,163,872,1064,835,1100,77,2139,717,946,346,93,1822,1601,1174,363,407,910,2275,198,805,2693,242,918,173,1834,368,330,66,2389,239,1154,1702,1331,2933,1238,733,465 | -0.20728341801373437,0.37323082292864296,-0.2492604414061187,1.4806368149043725,0.12601197226717611,0.7197788815940095,0.022324505727692668,-0.14445310808685582,0.20866925843125922,0.14670037120281113,0.5164299238420278,1.0222645998514908,-0.5027007309924332,-0.33343552863307785,-0.01926704960112091,-0.5239474963343811,0.20866925843125922,1.1224519125778383,0.6995066854647584,1.618928329270631,1.6780316249499048,0.18802891238331532,-0.06092655176681376,0.6182798801100748,0.37323082292864296,1.0222645998514908,0.3937322929558605,0.8411280257469278,0.5368284738518867,1.4212012137589964,-0.37563575123099097,1.1224519125778383,-1.7972284475701508,0.2499026019446144,0.5368284738518867,2.399390495804993,-0.16537868346442086,0.921762273203752,1.1824164060489466,0.8814712891547717,0.7805138743060999,1.2422720024056197,0.2499026019446144,0.14670037120281113,0.27049579609526114,0.12601197226717611,2.0891147678360613,-0.35452613486786577,0.352714297145243,0.20866925843125922,0.7400374285311478,1.8939254041622147,-0.20728341801373437,-0.10265492269446272,0.08458639893558295,0.7197788815940095,0.6589210414523182,0.2292937886448734,-0.4390800866390325,1.1224519125778383,0.2910734677256283,-0.9100071940702691,0.9620015287859891,0.2292937886448734,1.202380291141655,-0.20728341801373437,0.7197788815940095,0.7805138743060999,2.3607380919625607,-0.5239474963343811,0.9821019275934442,0.10530734984835549,-0.14445310808685582,0.022324505727692668,-4.163068613869287,0.06384901323418327,0.352714297145243,0.597938284242163 | 2,945 |
mRNA splicing factor | 28 | 56 | 3.126889 | 0.001767 | O75934,Q15233,Q07666,Q16629,Q08170,P19338,Q8WWY3,Q8IWZ8,Q96E39,Q92804,Q12874,Q96PK6,P98179,Q96PU8,P62995,Q07955,Q13242,P23246,Q14011,Q13595,Q01844,Q9BWF3,P38159,Q15637,P35637,Q15459,Q9Y4C8,O75494 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 374,517,273,407,163,532,432,566,173,180,562,188,61,330,197,324,77,333,93,346,226,239,109,363,115,518,527,127 | 576,2648,1382,1793,127,1125,374,1387,930,1092,863,1167,532,333,2096,115,109,1680,1142,2793,2663,197,871,61,226,273,324,163,872,1100,562,77,2139,717,346,93,1725,517,1766,518,363,407,1873,566,1686,432,722,180,173,188,330,239,2334,2192,527,2812 | 0.4755894045159319,-0.845166484742484,-0.01926704960112091,-0.20728341801373437,1.4806368149043725,0.10530734984835549,0.6995066854647584,-0.01926704960112091,0.20866925843125922,0.12601197226717611,0.2499026019446144,0.08458639893558295,0.5164299238420278,0.7602824013383189,-0.33343552863307785,1.618928329270631,1.6780316249499048,-0.14445310808685582,0.10530734984835549,-1.2154867397644784,-0.8667569312531026,1.1224519125778383,0.2499026019446144,2.399390495804993,1.0222645998514908,0.8814712891547717,0.7805138743060999,1.2422720024056197,0.2499026019446144,0.12601197226717611,0.49601692885848886,2.0891147678360613,-0.35452613486786577,0.352714297145243,0.7400374285311478,1.8939254041622147,-0.16537868346442086,0.5368284738518867,-0.18632207833549766,0.5368284738518867,0.7197788815940095,0.6589210414523182,-0.22826282947820883,0.49601692885848886,-0.14445310808685582,0.6386074394794051,0.352714297145243,1.1824164060489466,1.202380291141655,1.142452277500605,0.7805138743060999,0.9821019275934442,-0.4814740099977851,-0.37563575123099097,0.5368284738518867,-1.2595390174555432 | 2,945 |
Incomplete penetrance | 9 | 28 | 3.09899 | 0.001942 | Q969G3,P03886,O14979,P42224,P00846,O60313,P21912,Q92733,Q06787 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 257,2,132,238,18,174,119,124,254 | 132,680,174,973,1527,18,2,1014,119,2001,2002,1955,238,1590,711,1756,2672,254,1444,1873,432,124,257,1702,755,1513,462,260 | 1.4212012137589964,0.37323082292864296,1.1824164060489466,0.18802891238331532,-0.08178207009671594,4.364245678303629,7.077162194942315,0.1673726504047501,1.5794717175274886,-0.29131079005371857,-0.29131079005371857,-0.2702763842063141,0.9821019275934442,-0.10265492269446272,0.352714297145243,-0.18632207833549766,-0.8883704331508439,0.921762273203752,-0.04008825025596049,-0.22826282947820883,0.6386074394794051,1.5202041804528397,0.921762273203752,-0.14445310808685582,0.33218262437609547,-0.06092655176681376,0.597938284242163,0.921762273203752 | 2,945 |
Headache | 13 | 62 | 3.045007 | 0.002327 | Q969G3,P03886,Q9UMX1,O15460,P00403,Q9NQZ5,P00846,O60313,P21912,Q9NZ08,Q969N2,Q8NFH4,Q8TAA9 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 257,2,260,100,166,42,18,174,119,22,152,320,221 | 1991,678,1522,100,680,174,1996,2719,166,2123,18,739,2,2746,1668,1245,1014,530,2456,827,119,1477,533,1750,2001,1955,2486,902,1716,490,1756,2347,2270,1022,712,2062,906,2017,405,1913,2066,950,2643,2760,538,2110,327,320,221,959,1689,1322,257,152,1415,1929,42,1419,22,757,260,1379 | -0.29131079005371857,0.37323082292864296,-0.08178207009671594,1.7763226939226555,0.37323082292864296,1.1824164060489466,-0.29131079005371857,-0.9967910215997426,1.2223321368163933,-0.35452613486786577,4.364245678303629,0.33218262437609547,7.077162194942315,-1.0839642060391366,-0.14445310808685582,0.04309508514240472,0.1673726504047501,0.5164299238420278,-0.587809634186986,0.27049579609526114,1.5794717175274886,-0.06092655176681376,0.5164299238420278,-0.18632207833549766,-0.29131079005371857,-0.2702763842063141,-0.609138164405286,0.2292937886448734,-0.16537868346442086,0.5572126623575777,-0.18632207833549766,-0.5027007309924332,-0.4390800866390325,0.1673726504047501,0.352714297145243,-0.31236379292464844,0.2292937886448734,-0.29131079005371857,0.6589210414523182,-0.2492604414061187,-0.31236379292464844,0.20866925843125922,-0.8235988933073602,-1.105820052560868,0.5164299238420278,-0.33343552863307785,0.7805138743060999,0.8007319209650764,1.0423270044122548,0.20866925843125922,-0.14445310808685582,0.022324505727692668,0.921762273203752,1.2821160279306807,-0.01926704960112091,-0.2492604414061187,2.8795263015006634,-0.01926704960112091,3.824492664661767,0.33218262437609547,0.921762273203752,0.001537164702395684 | 2,945 |
Peptidyl proline modification | 10 | 31 | 3.043327 | 0.00234 | Q9Y680,O15460,Q32P28,Q96AY3,P13674,Q13451,P62942,Q02790,Q9NWM8,Q9BV86 | Processes and pathways | GO Biological process | msigdb_gobp | 98,100,136,19,176,83,25,58,59,62 | 1991,100,1992,388,418,176,2592,1131,2295,1857,2593,1590,25,801,58,2699,583,83,1147,1866,136,219,521,19,783,586,62,59,1281,613,98 | -0.29131079005371857,1.7763226939226555,-0.29131079005371857,0.6792207642978566,0.6386074394794051,1.1824164060489466,-0.7375531840373677,0.10530734984835549,-0.4602671791946553,-0.22826282947820883,-0.7375531840373677,-0.10265492269446272,3.768324465880385,0.2910734677256283,2.438006058944413,-0.9316674210504035,0.4755894045159319,1.9916454712619938,0.10530734984835549,-0.22826282947820883,1.4013665868313239,1.0423270044122548,0.5368284738518867,4.34572728753516,0.3116357123478239,0.4755894045159319,2.399390495804993,2.438006058944413,0.04309508514240472,0.4551472654983724,1.835170758534991 | 2,945 |
FDA approved drug targets | 19 | 119 | 3.043118 | 0.002341 | P00374,P03886,P09525,Q99720,Q16836,P48735,P62942,Q07864,Q13547,Q96QD8,P05091,Q16850,P55011,P21281,P35610,Q8N0U8,Q13423,P23634,Q9NRF9 | Functions | Protein Atlas Protein class | protein_atlas_protein_class | 1,2,133,8,138,145,25,162,54,66,67,101,232,105,107,110,112,240,247 | 1845,854,1621,1708,400,858,595,738,2574,1,1529,1127,1746,2825,2481,2,2773,862,2228,2631,1090,67,2747,1091,2342,1341,1246,2670,2601,133,1342,1624,2831,1198,2232,2202,2456,2807,1473,2260,2498,792,2233,2235,1129,2126,683,314,261,105,2174,1391,1346,2175,2430,240,1477,2091,2484,2177,1055,2264,829,2094,2756,1954,1132,2295,1750,555,1299,107,2097,2435,2486,1859,1675,1587,145,1811,1716,765,469,2580,2869,1059,1305,1485,232,25,1062,2561,2439,1026,2440,162,112,1262,1146,54,1313,688,2325,1318,2108,1176,138,101,110,2467,1112,66,477,2074,8,384,247,2874,2798 | -0.22826282947820883,0.2499026019446144,-0.12354522852272666,-0.16537868346442086,0.6589210414523182,0.2499026019446144,0.4551472654983724,0.33218262437609547,-0.7160969742146781,7.448017023011698,-0.08178207009671594,0.10530734984835549,-0.18632207833549766,-1.3701528148541127,-0.609138164405286,7.077162194942315,-1.1496084842326584,0.2499026019446144,-0.417912582552414,-0.8020539598800626,0.12601197226717611,2.341397984173776,-1.0839642060391366,0.12601197226717611,-0.5027007309924332,0.001537164702395684,0.04309508514240472,-0.8883704331508439,-0.7590312945413134,1.4212012137589964,0.001537164702395684,-0.12354522852272666,-1.3923607141779688,0.06384901323418327,-0.417912582552414,-0.3967645192768137,-0.587809634186986,-1.2595390174555432,-0.06092655176681376,-0.4390800866390325,-0.6304875446399937,0.2910734677256283,-0.417912582552414,-0.417912582552414,0.10530734984835549,-0.35452613486786577,0.37323082292864296,0.8007319209650764,0.9016232814114782,1.7370381436593936,-0.37563575123099097,-0.01926704960112091,0.001537164702395684,-0.37563575123099097,-0.5665017880289501,0.9620015287859891,-0.06092655176681376,-0.33343552863307785,-0.609138164405286,-0.37563575123099097,0.14670037120281113,-0.4390800866390325,0.27049579609526114,-0.33343552863307785,-1.105820052560868,-0.2702763842063141,0.10530734984835549,-0.4602671791946553,-0.18632207833549766,0.49601692885848886,0.022324505727692668,1.7173799770740772,-0.33343552863307785,-0.5665017880289501,-0.609138164405286,-0.22826282947820883,-0.14445310808685582,-0.10265492269446272,1.321912831571934,-0.20728341801373437,-0.16537868346442086,0.3116357123478239,0.5775825719273033,-0.7160969742146781,-1.7064250666788545,0.14670037120281113,0.022324505727692668,-0.06092655176681376,1.0021895959906988,3.768324465880385,0.14670037120281113,-0.6946624831235061,-0.5665017880289501,0.1673726504047501,-0.5665017880289501,1.2422720024056197,1.6583413438014383,0.04309508514240472,0.10530734984835549,2.4765850676126675,0.022324505727692668,0.37323082292864296,-0.4814740099977851,0.022324505727692668,-0.33343552863307785,0.08458639893558295,1.3815204900608,1.7763226939226555,1.6780316249499048,-0.587809634186986,0.12601197226717611,2.3607380919625607,0.5775825719273033,-0.31236379292464844,5.500372154885624,0.6995066854647584,0.9620015287859891,-1.751769488181549,-1.2154867397644784 | 2,945 |
FDA approved drug targets | 19 | 119 | 3.043118 | 0.002341 | P00374,P03886,P09525,Q99720,Q16836,P48735,P62942,Q07864,Q13547,Q96QD8,P05091,Q16850,P55011,P21281,P35610,Q8N0U8,Q13423,P23634,Q9NRF9 | Drugs and Diseases | Protein Atlas Disease involvement | protein_atlas_disease_involvement | 1,2,133,8,138,145,25,162,54,66,67,101,232,105,107,110,112,240,247 | 1845,854,1621,1708,400,858,595,738,2574,1,1529,1127,1746,2825,2481,2,2773,862,2228,2631,1090,67,2747,1091,2342,1341,1246,2670,2601,133,1342,1624,2831,1198,2232,2202,2456,2807,1473,2260,2498,792,2233,2235,1129,2126,683,314,261,105,2174,1391,1346,2175,2430,240,1477,2091,2484,2177,1055,2264,829,2094,2756,1954,1132,2295,1750,555,1299,107,2097,2435,2486,1859,1675,1587,145,1811,1716,765,469,2580,2869,1059,1305,1485,232,25,1062,2561,2439,1026,2440,162,112,1262,1146,54,1313,688,2325,1318,2108,1176,138,101,110,2467,1112,66,477,2074,8,384,247,2874,2798 | -0.22826282947820883,0.2499026019446144,-0.12354522852272666,-0.16537868346442086,0.6589210414523182,0.2499026019446144,0.4551472654983724,0.33218262437609547,-0.7160969742146781,7.448017023011698,-0.08178207009671594,0.10530734984835549,-0.18632207833549766,-1.3701528148541127,-0.609138164405286,7.077162194942315,-1.1496084842326584,0.2499026019446144,-0.417912582552414,-0.8020539598800626,0.12601197226717611,2.341397984173776,-1.0839642060391366,0.12601197226717611,-0.5027007309924332,0.001537164702395684,0.04309508514240472,-0.8883704331508439,-0.7590312945413134,1.4212012137589964,0.001537164702395684,-0.12354522852272666,-1.3923607141779688,0.06384901323418327,-0.417912582552414,-0.3967645192768137,-0.587809634186986,-1.2595390174555432,-0.06092655176681376,-0.4390800866390325,-0.6304875446399937,0.2910734677256283,-0.417912582552414,-0.417912582552414,0.10530734984835549,-0.35452613486786577,0.37323082292864296,0.8007319209650764,0.9016232814114782,1.7370381436593936,-0.37563575123099097,-0.01926704960112091,0.001537164702395684,-0.37563575123099097,-0.5665017880289501,0.9620015287859891,-0.06092655176681376,-0.33343552863307785,-0.609138164405286,-0.37563575123099097,0.14670037120281113,-0.4390800866390325,0.27049579609526114,-0.33343552863307785,-1.105820052560868,-0.2702763842063141,0.10530734984835549,-0.4602671791946553,-0.18632207833549766,0.49601692885848886,0.022324505727692668,1.7173799770740772,-0.33343552863307785,-0.5665017880289501,-0.609138164405286,-0.22826282947820883,-0.14445310808685582,-0.10265492269446272,1.321912831571934,-0.20728341801373437,-0.16537868346442086,0.3116357123478239,0.5775825719273033,-0.7160969742146781,-1.7064250666788545,0.14670037120281113,0.022324505727692668,-0.06092655176681376,1.0021895959906988,3.768324465880385,0.14670037120281113,-0.6946624831235061,-0.5665017880289501,0.1673726504047501,-0.5665017880289501,1.2422720024056197,1.6583413438014383,0.04309508514240472,0.10530734984835549,2.4765850676126675,0.022324505727692668,0.37323082292864296,-0.4814740099977851,0.022324505727692668,-0.33343552863307785,0.08458639893558295,1.3815204900608,1.7763226939226555,1.6780316249499048,-0.587809634186986,0.12601197226717611,2.3607380919625607,0.5775825719273033,-0.31236379292464844,5.500372154885624,0.6995066854647584,0.9620015287859891,-1.751769488181549,-1.2154867397644784 | 2,945 |
Peptidyl amino acid modification | 37 | 229 | 3.001837 | 0.002684 | Q32P28,P31751,Q03164,Q9H7B4,Q9NYU2,Q96AY3,Q04656,Q9UBU8,P62942,O95684,O95251,O95429,Q01105,P13674,O14641,Q02790,Q9NWM8,Q9BV86,P04843,Q7L592,O95696,Q9NWT6,P49593,O75844,Q8N4A0,Q13451,Q05397,Q13432,Q5T1M5,Q92791,Q9Y680,O15460,Q8N0U8,Q8TCJ2,P23634,Q9UIV1,Q9NRF9 | Processes and pathways | GO Biological process | msigdb_gobp | 136,262,13,14,143,19,148,278,25,24,155,156,170,176,181,58,59,62,184,65,194,204,202,80,82,83,217,218,219,92,98,100,110,111,240,117,247 | 1990,1991,735,181,1787,854,1574,1123,100,1992,2650,1085,511,400,1948,2687,388,80,155,156,24,194,860,1290,1905,1796,1165,790,2481,2228,1668,184,791,929,418,900,2670,1197,2231,1342,2538,1748,1198,2576,176,2913,2294,1711,402,1296,1345,1855,2371,1347,1798,1628,2592,240,795,2484,1131,2177,1856,2094,685,617,2295,1857,2296,262,1351,2577,2001,1019,936,1859,2593,2099,489,1253,1394,1479,980,1538,202,1590,1591,1539,2621,982,2132,799,2182,1485,1257,2300,2581,2013,25,2742,2104,2878,1721,2348,801,170,1026,58,404,13,537,148,217,492,2459,2460,2699,908,2065,642,1443,583,516,1360,1310,1763,218,83,1262,1147,1066,2710,946,1101,393,1173,1866,496,2884,643,2867,623,2848,952,666,1403,1027,136,1967,219,667,603,565,2384,1407,2142,65,913,296,1075,1320,2893,2704,1368,110,2386,82,2465,111,521,1688,2467,92,1606,994,19,783,586,1153,1692,674,1836,1774,2682,2254,1775,1693,434,2548,62,2034,1231,1001,2190,1653,2393,2695,1842,545,2360,1455,2645,1739,14,506,247,920,755,59,1613,204,143,1615,1003,1463,278,2874,1617,117,2045,1936,851,1281,2364,2496,613,924,98,466 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| 2,945 |
Abnormal urine ph | 7 | 43 | 2.978457 | 0.002897 | P03886,O43772,Q9H845,Q16836,P11310,P00846,O96000 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 2,34,70,138,11,18,63 | 34,1903,63,18,2,2830,1243,2231,11,2456,2234,1168,1346,1477,1673,2002,1752,1808,145,1137,2132,1592,2346,869,405,2108,138,285,538,782,1322,1152,750,2860,1327,70,2570,2684,2765,2810,2225,2197,1517 | 3.392192755458683,-0.2492604414061187,2.3800689170256426,4.364245678303629,7.077162194942315,-1.3923607141779688,0.04309508514240472,-0.417912582552414,4.9168542761704375,-0.587809634186986,-0.417912582552414,0.08458639893558295,0.001537164702395684,-0.06092655176681376,-0.14445310808685582,-0.29131079005371857,-0.18632207833549766,-0.20728341801373437,1.321912831571934,0.10530734984835549,-0.35452613486786577,-0.10265492269446272,-0.5027007309924332,0.2499026019446144,0.6589210414523182,-0.33343552863307785,1.3815204900608,0.8613062272321225,0.5164299238420278,0.3116357123478239,0.022324505727692668,0.10530734984835549,0.33218262437609547,-1.6386272017792467,0.022324505727692668,2.2057541946060866,-0.6946624831235061,-0.8883704331508439,-1.105820052560868,-1.2595390174555432,-0.3967645192768137,-0.37563575123099097,-0.06092655176681376 | 2,945 |
Limb joint contracture | 20 | 87 | 2.944462 | 0.003235 | Q15392,Q99720,Q08J23,P37268,P42892,Q96AY3,Q02809,P16435,P49902,Q86XL3,Q9Y619,O60313,P50402,Q9ULC3,O00330,O75844,Q96T58,Q8TD16,P35637,P21912 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 5,8,392,12,264,19,404,402,282,46,50,174,315,445,193,80,208,87,115,119 | 193,1706,1791,2400,174,1049,682,1124,2258,80,1008,2453,554,790,1245,2125,2236,402,706,2372,119,2127,1477,1630,2094,1750,2058,115,1252,12,1134,2060,264,2520,2436,282,315,982,1910,712,1760,2722,404,985,392,1146,774,2381,1067,948,1724,2610,1316,2638,5,1920,1447,2817,46,605,2278,460,806,87,959,625,1227,1452,19,208,1034,8,2712,2745,2191,2754,2684,1777,787,445,1241,2049,2480,1335,2451,50,1520 | 1.1224519125778383,-0.16537868346442086,-0.20728341801373437,-0.5452144624387532,1.1824164060489466,0.14670037120281113,0.37323082292864296,0.10530734984835549,-0.4390800866390325,2.0501568052051606,0.1673726504047501,-0.587809634186986,0.49601692885848886,0.2910734677256283,0.04309508514240472,-0.35452613486786577,-0.417912582552414,0.6589210414523182,0.352714297145243,-0.5239474963343811,1.5794717175274886,-0.35452613486786577,-0.06092655176681376,-0.12354522852272666,-0.33343552863307785,-0.18632207833549766,-0.31236379292464844,1.618928329270631,0.04309508514240472,4.770037134790452,0.10530734984835549,-0.31236379292464844,0.9016232814114782,-0.6518579433658428,-0.5665017880289501,0.8613062272321225,0.8007319209650764,0.18802891238331532,-0.2492604414061187,0.352714297145243,-0.18632207833549766,-0.9967910215997426,0.6589210414523182,0.18802891238331532,0.6792207642978566,0.10530734984835549,0.3116357123478239,-0.5239474963343811,0.14670037120281113,0.20866925843125922,-0.16537868346442086,-0.7590312945413134,0.022324505727692668,-0.8020539598800626,5.735788324107087,-0.2492604414061187,-0.04008825025596049,-1.3037005802478918,2.841314827134973,0.4551472654983724,-0.4390800866390325,0.597938284242163,0.2910734677256283,1.9525878342172756,0.20866925843125922,0.4346904255440359,0.06384901323418327,-0.04008825025596049,4.34572728753516,1.0824142734467934,0.1673726504047501,5.500372154885624,-0.9533513246189271,-1.0621336151647116,-0.37563575123099097,-1.0839642060391366,-0.8883704331508439,-0.18632207833549766,0.3116357123478239,0.6182798801100748,0.06384901323418327,-0.29131079005371857,-0.587809634186986,0.022324505727692668,-0.5665017880289501,2.592105567404909,-0.06092655176681376 | 2,945 |
Diseases of signal transduction by growth factor receptors and second messengers | 35 | 142 | 2.930997 | 0.003379 | P25787,Q86TM6,P30086,P31751,P20618,P62942,O95684,P62140,O95429,P28070,P25054,P10644,P30154,Q9UQ13,P51665,O00231,P19174,Q13547,Q01082,P51114,P16220,P49589,Q96PU8,P60900,P28072,P52434,P61289,P49721,Q13555,Q99436,Q9GZP9,P13984,P42224,P62993,Q6UN15 | Processes and pathways | Reactome Pathways | msigdb_reactome | 3,520,9,262,261,25,24,403,156,31,533,530,294,308,561,550,53,54,440,439,437,560,330,196,69,322,580,469,473,504,369,106,238,491,125 | 1426,550,2398,2163,1523,1337,759,760,1622,1008,1196,156,24,790,763,1245,900,2670,530,578,106,437,1672,1130,53,793,261,827,1628,2344,533,1249,3,1533,2483,1250,1098,2177,1631,31,69,829,2094,9,617,294,2000,262,1299,830,640,2001,977,978,742,2318,1134,936,238,1859,1809,1136,2578,1479,560,2505,469,1590,1591,1539,439,982,561,322,1306,1679,870,196,580,403,1863,1638,1595,2407,2303,1681,25,491,1864,2523,1260,1209,944,440,1026,2459,2244,664,773,872,1210,1310,54,473,2710,946,2020,718,948,2463,2750,1265,1919,1212,2723,125,1108,1109,2329,520,1730,1367,2279,2029,1321,2467,2821,330,963,504,1114,1837,369,2079,2707,849,755,1422,1237,1568,308,1896 | -0.04008825025596049,0.49601692885848886,-0.5452144624387532,-0.37563575123099097,-0.08178207009671594,0.001537164702395684,0.3116357123478239,0.3116357123478239,-0.12354522852272666,0.1673726504047501,0.06384901323418327,1.262199946694982,3.768324465880385,0.2910734677256283,0.3116357123478239,0.04309508514240472,0.2292937886448734,-0.8883704331508439,0.5164299238420278,0.4755894045159319,1.7173799770740772,0.6182798801100748,-0.14445310808685582,0.10530734984835549,2.4765850676126675,0.2910734677256283,0.9016232814114782,0.27049579609526114,-0.12354522852272666,-0.5027007309924332,0.5164299238420278,0.04309508514240472,6.86435802761024,-0.08178207009671594,-0.609138164405286,0.04309508514240472,0.12601197226717611,-0.37563575123099097,-0.12354522852272666,3.5053441140537633,2.2639439873853995,0.27049579609526114,-0.33343552863307785,5.445914220137767,0.4346904255440359,0.8411280257469278,-0.29131079005371857,0.9016232814114782,0.022324505727692668,0.27049579609526114,0.4142187974298949,-0.29131079005371857,0.18802891238331532,0.18802891238331532,0.33218262437609547,-0.4814740099977851,0.10530734984835549,0.20866925843125922,0.9821019275934442,-0.22826282947820883,-0.20728341801373437,0.10530734984835549,-0.7160969742146781,-0.06092655176681376,0.49601692885848886,-0.6304875446399937,0.5775825719273033,-0.10265492269446272,-0.10265492269446272,-0.08178207009671594,0.6182798801100748,0.18802891238331532,0.49601692885848886,0.7805138743060999,0.022324505727692668,-0.14445310808685582,0.2499026019446144,1.1224519125778383,0.4755894045159319,0.6589210414523182,-0.22826282947820883,-0.12354522852272666,-0.10265492269446272,-0.5452144624387532,-0.4602671791946553,-0.14445310808685582,3.768324465880385,0.5572126623575777,-0.22826282947820883,-0.6518579433658428,0.04309508514240472,0.06384901323418327,0.20866925843125922,0.6182798801100748,0.1673726504047501,-0.587809634186986,-0.417912582552414,0.3937322929558605,0.3116357123478239,0.2499026019446144,0.06384901323418327,0.022324505727692668,2.4765850676126675,0.5775825719273033,-0.9533513246189271,0.20866925843125922,-0.29131079005371857,0.352714297145243,0.20866925843125922,-0.587809634186986,-1.0839642060391366,0.04309508514240472,-0.2492604414061187,0.06384901323418327,-0.9967910215997426,1.5004260995112062,0.12601197226717611,0.12601197226717611,-0.4814740099977851,0.5368284738518867,-0.16537868346442086,0.001537164702395684,-0.4390800866390325,-0.29131079005371857,0.022324505727692668,-0.587809634186986,-1.3479736939343891,0.7805138743060999,0.20866925843125922,0.5572126623575777,0.12601197226717611,-0.20728341801373437,0.7197788815940095,-0.31236379292464844,-0.9316674210504035,0.27049579609526114,0.33218262437609547,-0.01926704960112091,0.06384901323418327,-0.08178207009671594,0.8209366140972024,-0.22826282947820883 | 2,945 |
Tetratricopeptide-like helical domain superfamily [IPR011990] | 29 | 81 | 2.925001 | 0.003445 | Q32P28,A0AVF1,Q9H7B4,Q12797,O75718,Q9NSK0,Q9H0B6,Q96EK5,Q6DKK2,O15091,Q6PD62,Q13042,P13674,O00231,Q02790,O00411,O76024,O75153,Q9H270,Q99747,Q13451,Q9NYH9,Q9Y262,Q92791,Q5R3I4,O15460,Q14CX7,Q13217,Q96TC7 | Sequence | InterPro Superfamily | interpro_homologous_superfamily | 136,635,14,642,388,147,544,409,426,657,565,179,176,550,58,310,76,78,339,608,83,214,612,92,351,100,496,241,126 | 635,1991,550,310,1427,657,1123,100,1337,2649,78,388,76,2341,1007,1387,1088,176,1801,1858,1351,1859,1056,710,1590,1304,2487,1259,944,58,773,2699,642,1442,179,241,83,1866,2067,496,2544,1265,1725,1823,136,351,426,565,691,1971,2218,807,92,2281,1323,409,1690,126,2032,2073,608,1001,2334,544,339,1375,2035,14,2803,2192,147,214,2082,1893,1234,1424,612,1465,1939,925,1122 | 0.4142187974298949,-0.29131079005371857,0.49601692885848886,0.8007319209650764,-0.04008825025596049,0.3937322929558605,0.10530734984835549,1.7763226939226555,0.001537164702395684,-0.845166484742484,2.0696407183096763,0.6792207642978566,2.0891147678360613,-0.5027007309924332,0.1673726504047501,-0.01926704960112091,0.12601197226717611,1.1824164060489466,-0.20728341801373437,-0.22826282947820883,0.001537164702395684,-0.22826282947820883,0.14670037120281113,0.352714297145243,-0.10265492269446272,0.022324505727692668,-0.609138164405286,0.04309508514240472,0.20866925843125922,2.438006058944413,0.3116357123478239,-0.9316674210504035,0.4142187974298949,-0.04008825025596049,1.1824164060489466,0.9620015287859891,1.9916454712619938,-0.22826282947820883,-0.31236379292464844,0.5572126623575777,-0.6732495316326513,0.04309508514240472,-0.16537868346442086,-0.20728341801373437,1.4013665868313239,0.7400374285311478,0.6386074394794051,0.49601692885848886,0.37323082292864296,-0.2702763842063141,-0.3967645192768137,0.2910734677256283,1.9134897350999418,-0.4390800866390325,0.022324505727692668,0.6589210414523182,-0.14445310808685582,1.5004260995112062,-0.29131079005371857,-0.31236379292464844,0.4551472654983724,0.18802891238331532,-0.4814740099977851,0.5164299238420278,0.7602824013383189,0.001537164702395684,-0.29131079005371857,4.62282865259948,-1.2374993562115237,-0.37563575123099097,1.321912831571934,1.062376874281129,-0.31236379292464844,-0.22826282947820883,0.06384901323418327,-0.01926704960112091,0.4551472654983724,-0.04008825025596049,-0.2492604414061187,0.2292937886448734,0.12601197226717611 | 2,945 |
Repressor | 31 | 101 | 2.910844 | 0.003605 | P67809,P61978,O14979,Q9HCD5,Q9GZT3,Q8N163,Q8NB78,Q16629,P49750,Q08170,Q8NEY8,Q9NYF8,Q13547,Q96PK6,P62995,Q86YP4,Q13242,Q96T58,P23246,Q9NX63,Q8IZL8,Q14011,Q9UBK9,Q9HD42,Q01844,Q9UHR5,P38159,Q15637,Q9UIV1,Q13217,Q06787 | Functions | Protein Atlas Molecular function | protein_atlas_molecular_function | 129,134,132,269,146,277,21,407,157,163,431,306,54,188,197,459,77,208,333,355,352,93,95,385,226,235,109,363,117,241,254 | 2288,735,968,1786,1787,1428,132,1195,2120,856,2650,928,1668,2403,1294,1345,333,2484,2092,1392,2557,2094,109,1674,157,905,982,767,870,134,197,129,1061,2652,1722,226,1545,664,254,163,1100,2018,987,241,77,717,1360,493,1310,54,93,2245,1764,2610,517,1726,363,407,456,1030,2328,459,841,2250,1770,352,277,21,431,722,884,1688,2467,188,1186,208,1924,2332,1982,2114,1607,146,2597,695,269,1456,385,755,2614,355,306,95,235,2933,117,2043,1782,1844,2571,2479,924 | -0.4602671791946553,0.33218262437609547,0.18802891238331532,-0.20728341801373437,-0.20728341801373437,-0.04008825025596049,1.4212012137589964,0.06384901323418327,-0.35452613486786577,0.2499026019446144,-0.845166484742484,0.20866925843125922,-0.14445310808685582,-0.5452144624387532,0.022324505727692668,0.001537164702395684,0.7602824013383189,-0.609138164405286,-0.33343552863307785,-0.01926704960112091,-0.6946624831235061,-0.33343552863307785,1.6780316249499048,-0.14445310808685582,1.262199946694982,0.2292937886448734,0.18802891238331532,0.3116357123478239,0.2499026019446144,1.4212012137589964,1.1224519125778383,1.4410244250244986,0.14670037120281113,-0.845166484742484,-0.16537868346442086,1.0222645998514908,-0.08178207009671594,0.3937322929558605,0.921762273203752,1.2422720024056197,0.12601197226717611,-0.29131079005371857,0.18802891238331532,0.9620015287859891,2.0891147678360613,0.352714297145243,0.001537164702395684,0.5572126623575777,0.022324505727692668,2.4765850676126675,1.8939254041622147,-0.417912582552414,-0.18632207833549766,-0.7590312945413134,0.5368284738518867,-0.16537868346442086,0.7197788815940095,0.6589210414523182,0.597938284242163,0.1673726504047501,-0.4814740099977851,0.597938284242163,0.27049579609526114,-0.417912582552414,-0.18632207833549766,0.7400374285311478,0.8814712891547717,4.01126221185754,0.6386074394794051,0.352714297145243,0.2499026019446144,-0.14445310808685582,-0.587809634186986,1.142452277500605,0.08458639893558295,1.0824142734467934,-0.2492604414061187,-0.4814740099977851,-0.2702763842063141,-0.33343552863307785,-0.10265492269446272,1.321912831571934,-0.7375531840373677,0.37323082292864296,0.9016232814114782,-0.04008825025596049,0.6995066854647584,0.33218262437609547,-0.7590312945413134,0.7400374285311478,0.8209366140972024,1.8743508272867104,1.0021895959906988,-4.163068613869287,1.618928329270631,-0.29131079005371857,-0.18632207833549766,-0.20728341801373437,-0.6946624831235061,-0.587809634186986,0.2292937886448734 | 2,945 |
Alcohol metabolic process | 14 | 79 | 2.890418 | 0.003847 | Q8WTV0,P00374,P05091,Q15392,Q9BY49,Q16850,P35610,P37268,O94788,Q9BQE5,P61457,P30837,P48449,Q14739 | Processes and pathways | GO Biological process | msigdb_gobp | 32,1,67,5,37,101,107,12,49,51,86,55,91,29 | 2659,1336,1788,1286,2553,1468,1049,825,595,49,1008,2799,1,2719,2773,2746,67,2556,1852,2576,2235,2203,2126,402,2172,2237,55,512,271,107,12,1202,557,91,145,1137,2580,2008,982,868,1059,1485,2801,86,2826,1359,1819,2063,2722,405,1963,2929,2019,2897,2524,1313,29,1867,2350,5,2653,2847,1028,101,1072,337,2819,2466,32,2682,2778,51,846,37,2685,2628,435,342,2854 | -0.8667569312531026,0.001537164702395684,-0.20728341801373437,0.022324505727692668,-0.6946624831235061,-0.06092655176681376,0.14670037120281113,0.27049579609526114,0.4551472654983724,2.6113277676568396,0.1673726504047501,-1.2374993562115237,7.448017023011698,-0.9967910215997426,-1.1496084842326584,-1.0839642060391366,2.341397984173776,-0.6946624831235061,-0.22826282947820883,-0.7160969742146781,-0.417912582552414,-0.3967645192768137,-0.35452613486786577,0.6589210414523182,-0.37563575123099097,-0.417912582552414,2.4573001148610345,0.5368284738518867,0.8814712891547717,1.7173799770740772,4.770037134790452,0.06384901323418327,0.49601692885848886,1.9134897350999418,1.321912831571934,0.10530734984835549,-0.7160969742146781,-0.29131079005371857,0.18802891238331532,0.2499026019446144,0.14670037120281113,-0.06092655176681376,-1.2374993562115237,1.9525878342172756,-1.3701528148541127,0.001537164702395684,-0.20728341801373437,-0.31236379292464844,-0.9967910215997426,0.6589210414523182,-0.2702763842063141,-3.571580495971794,-0.29131079005371857,-2.003165196484295,-0.6518579433658428,0.022324505727692668,3.655794126757704,-0.22826282947820883,-0.5027007309924332,5.735788324107087,-0.845166484742484,-1.5262302338877283,0.1673726504047501,1.7763226939226555,0.14670037120281113,0.7602824013383189,-1.3258230481672575,-0.587809634186986,3.5053441140537633,-0.8883704331508439,-1.1496084842326584,2.5151278038931033,0.27049579609526114,3.2408955872793364,-0.8883704331508439,-0.7805314905603624,0.6386074394794051,0.7602824013383189,-1.5710975994835399 | 2,945 |
Abnormality of thyroid physiology | 15 | 68 | 2.854819 | 0.004306 | Q969G3,P03886,Q9UMX1,P61978,P00403,P21281,O76024,P42224,Q07021,Q96T58,Q13423,O60313,Q9Y285,Q06787,Q15056 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 257,2,260,134,166,105,76,238,178,208,112,174,289,254,255 | 1991,678,1047,1706,2535,702,174,2087,1996,76,2453,899,166,2825,2,1997,530,2456,105,1391,487,533,1630,1803,2001,641,1019,1134,238,1482,769,1022,2377,134,1143,254,178,986,112,873,1361,1067,2068,255,302,2676,2069,691,1182,2611,672,1879,2188,257,208,2076,1841,1695,1378,1703,1617,787,260,1424,2047,289,1241,2647 | -0.29131079005371857,0.37323082292864296,0.14670037120281113,-0.16537868346442086,-0.6732495316326513,0.352714297145243,1.1824164060489466,-0.33343552863307785,-0.29131079005371857,2.0891147678360613,-0.587809634186986,0.2292937886448734,1.2223321368163933,-1.3701528148541127,7.077162194942315,-0.29131079005371857,0.5164299238420278,-0.587809634186986,1.7370381436593936,-0.01926704960112091,0.5572126623575777,0.5164299238420278,-0.12354522852272666,-0.20728341801373437,-0.29131079005371857,0.4142187974298949,0.1673726504047501,0.10530734984835549,0.9821019275934442,-0.06092655176681376,0.3116357123478239,0.1673726504047501,-0.5239474963343811,1.4212012137589964,0.10530734984835549,0.921762273203752,1.1824164060489466,0.18802891238331532,1.6583413438014383,0.2499026019446144,0.001537164702395684,0.14670037120281113,-0.31236379292464844,0.921762273203752,0.8209366140972024,-0.8883704331508439,-0.31236379292464844,0.37323082292864296,0.08458639893558295,-0.7590312945413134,0.3937322929558605,-0.22826282947820883,-0.37563575123099097,0.921762273203752,1.0824142734467934,-0.31236379292464844,-0.20728341801373437,-0.14445310808685582,0.001537164702395684,-0.14445310808685582,-0.10265492269446272,0.3116357123478239,0.921762273203752,-0.01926704960112091,-0.29131079005371857,0.8613062272321225,0.06384901323418327,-0.8235988933073602 | 2,945 |
Abnormal muscle fiber morphology | 19 | 67 | 2.803598 | 0.005054 | P03886,P61978,O14979,Q99720,Q70HW3,Q7Z406,P00846,Q86U42,Q02809,P00403,P43243,O60313,P50402,P51114,O95831,Q8N9N2,P22626,P09651,P35637 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 2,134,132,8,10,408,18,276,404,166,424,174,315,439,89,220,224,359,115 | 2257,2851,132,2918,2400,174,1124,89,2402,166,18,790,2,2591,1245,2230,359,1851,2456,661,2127,224,1477,1750,935,115,2060,424,2503,315,1058,439,2346,869,1679,134,404,985,2381,2563,1965,1362,2024,10,1074,408,276,220,1646,647,806,625,2513,8,2189,2734,2712,2076,1563,1696,2754,1512,654,1938,1044,482,1335 | -0.4390800866390325,-1.5710975994835399,1.4212012137589964,-2.894826421250636,-0.5452144624387532,1.1824164060489466,0.10530734984835549,1.9330438639514882,-0.5452144624387532,1.2223321368163933,4.364245678303629,0.2910734677256283,7.077162194942315,-0.7375531840373677,0.04309508514240472,-0.417912582552414,0.7197788815940095,-0.22826282947820883,-0.587809634186986,0.3937322929558605,-0.35452613486786577,1.0222645998514908,-0.06092655176681376,-0.18632207833549766,0.20866925843125922,1.618928329270631,-0.31236379292464844,0.6386074394794051,-0.6304875446399937,0.8007319209650764,0.14670037120281113,0.6182798801100748,-0.5027007309924332,0.2499026019446144,-0.14445310808685582,1.4212012137589964,0.6589210414523182,0.18802891238331532,-0.5239474963343811,-0.6946624831235061,-0.2702763842063141,0.001537164702395684,-0.29131079005371857,5.045004847981975,0.14670037120281113,0.6589210414523182,0.8814712891547717,1.0423270044122548,-0.12354522852272666,0.4142187974298949,0.2910734677256283,0.4346904255440359,-0.6304875446399937,5.500372154885624,-0.37563575123099097,-1.01854725430779,-0.9533513246189271,-0.31236379292464844,-0.08178207009671594,-0.14445310808685582,-1.0839642060391366,-0.06092655176681376,0.4142187974298949,-0.2492604414061187,0.1673726504047501,0.5775825719273033,0.022324505727692668 | 2,945 |
Spliceosomal complex | 44 | 112 | 2.792765 | 0.005226 | P31943,O75934,Q99459,P67809,P61978,O60306,P52272,P52756,P07910,P19338,P11940,Q8WWY3,Q8IWZ8,O43390,Q96E39,Q12874,P51991,Q14562,P98179,Q9Y5S9,Q9Y2W2,P31942,Q9UJV9,P62995,Q9P2K5,Q07955,O43290,O43172,Q13123,Q9Y3C6,O60506,Q14011,Q92620,Q13595,P52597,P22626,Q9Y3B4,Q96DF8,P38159,P09651,Q15637,Q13435,P41223,Q15459 | Localization | GO Cellular component | msigdb_gocc | 375,374,523,129,134,636,535,663,401,532,660,432,566,169,173,562,182,56,61,465,464,195,462,197,199,324,447,576,453,613,215,93,229,346,225,224,634,367,109,359,363,494,488,518 | 1790,576,447,169,2648,1992,1005,1382,2400,636,215,1006,1125,1050,374,1051,1387,401,930,1092,863,359,1167,1294,660,2171,933,532,224,2092,195,375,109,2003,488,1020,182,535,225,663,1438,1022,1256,134,1680,1142,2793,1440,2663,197,129,61,1722,2642,324,562,453,494,2410,946,346,1263,93,56,1765,1766,518,363,910,2070,2412,1729,912,1873,2072,1267,566,2693,1185,432,2827,960,229,1269,783,367,2566,173,694,2388,523,1608,2334,1416,1986,2192,1700,1703,1331,199,462,1236,1238,1937,464,1240,2697,1619,634,613,2812,465 | -0.20728341801373437,0.4755894045159319,0.597938284242163,1.202380291141655,-0.845166484742484,-0.29131079005371857,0.1673726504047501,-0.01926704960112091,-0.5452144624387532,0.4142187974298949,1.0423270044122548,0.1673726504047501,0.10530734984835549,0.14670037120281113,0.6995066854647584,0.14670037120281113,-0.01926704960112091,0.6589210414523182,0.20866925843125922,0.12601197226717611,0.2499026019446144,0.7197788815940095,0.08458639893558295,0.022324505727692668,0.3937322929558605,-0.37563575123099097,0.20866925843125922,0.5164299238420278,1.0222645998514908,-0.33343552863307785,1.1224519125778383,0.6995066854647584,1.6780316249499048,-0.29131079005371857,0.5572126623575777,0.1673726504047501,1.1624404216515005,0.5164299238420278,1.0222645998514908,0.3937322929558605,-0.04008825025596049,0.1673726504047501,0.04309508514240472,1.4212012137589964,-0.14445310808685582,0.10530734984835549,-1.2154867397644784,-0.04008825025596049,-0.8667569312531026,1.1224519125778383,1.4410244250244986,2.399390495804993,-0.16537868346442086,-0.8235988933073602,0.7805138743060999,0.49601692885848886,0.597938284242163,0.5572126623575777,-0.5452144624387532,0.20866925843125922,0.7400374285311478,0.04309508514240472,1.8939254041622147,2.4573001148610345,-0.18632207833549766,-0.18632207833549766,0.5368284738518867,0.7197788815940095,0.2292937886448734,-0.31236379292464844,-0.5452144624387532,-0.16537868346442086,0.2292937886448734,-0.22826282947820883,-0.31236379292464844,0.04309508514240472,0.49601692885848886,-0.9100071940702691,0.08458639893558295,0.6386074394794051,-1.3701528148541127,0.20866925843125922,1.0222645998514908,0.04309508514240472,0.3116357123478239,0.7197788815940095,-0.6946624831235061,1.202380291141655,0.37323082292864296,-0.5239474963343811,0.5368284738518867,-0.10265492269446272,-0.4814740099977851,-0.01926704960112091,-0.2702763842063141,-0.37563575123099097,-0.14445310808685582,-0.14445310808685582,0.022324505727692668,1.1224519125778383,0.597938284242163,0.06384901323418327,0.06384901323418327,-0.2492604414061187,0.597938284242163,0.06384901323418327,-0.9100071940702691,-0.10265492269446272,0.4346904255440359,0.4551472654983724,-1.2595390174555432,0.597938284242163 | 2,945 |
Endopeptidase activity | 13 | 63 | 2.78311 | 0.005384 | Q96E52,P60900,Q5JRX3,P28072,Q4J6C6,P42892,P20618,Q16740,O75844,Q92643,Q9NZ08,Q9Y4E8,P28070 | Functions | GO Molecular function | msigdb_gomf | 97,196,266,69,137,264,261,15,80,52,22,290,31 | 2843,2426,510,312,1383,80,1667,1166,1625,1129,1343,261,828,2483,31,69,829,1584,740,796,1675,264,1135,1810,2505,469,1678,1484,2319,1959,196,2408,1963,1443,2664,2106,2021,15,137,266,875,2788,429,2739,2029,52,1501,2188,626,97,1413,587,997,504,1274,1982,383,1697,22,2588,1425,290,1044 | -1.5038429397324582,-0.5665017880289501,0.5368284738518867,0.8007319209650764,-0.01926704960112091,2.0501568052051606,-0.14445310808685582,0.08458639893558295,-0.12354522852272666,0.10530734984835549,0.001537164702395684,0.9016232814114782,0.27049579609526114,-0.609138164405286,3.5053441140537633,2.2639439873853995,0.27049579609526114,-0.10265492269446272,0.33218262437609547,0.2910734677256283,-0.14445310808685582,0.9016232814114782,0.10530734984835549,-0.20728341801373437,-0.6304875446399937,0.5775825719273033,-0.14445310808685582,-0.06092655176681376,-0.4814740099977851,-0.2702763842063141,1.1224519125778383,-0.5452144624387532,-0.2702763842063141,-0.04008825025596049,-0.8667569312531026,-0.33343552863307785,-0.29131079005371857,4.53062075988975,1.4013665868313239,0.9016232814114782,0.2499026019446144,-1.1935008981215134,0.6386074394794051,-1.0403280423845351,-0.29131079005371857,2.4958609523307893,-0.06092655176681376,-0.37563575123099097,0.4346904255440359,1.8547659602664823,-0.01926704960112091,0.4755894045159319,0.18802891238331532,0.5572126623575777,0.04309508514240472,-0.2702763842063141,0.6995066854647584,-0.14445310808685582,3.824492664661767,-0.7160969742146781,-0.01926704960112091,0.8613062272321225,0.1673726504047501 | 2,945 |
Hypogonadism | 15 | 79 | 2.775104 | 0.005518 | Q92620,P03886,Q07864,Q969G3,P00403,Q4J6C6,O76024,Q16740,O75844,Q96T58,O60313,Q9H2M9,P48449,Q06787,Q15056 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 229,2,162,257,166,137,76,15,80,208,174,246,91,254,255 | 852,1991,678,1706,970,576,1791,2648,702,1468,174,1050,2688,80,76,1387,2453,899,166,790,2,1668,1624,530,706,1016,1628,1200,2001,641,1806,91,2436,1481,2580,2008,982,2009,1594,1143,1026,2459,254,162,774,1316,255,15,137,1873,605,1111,1183,672,432,229,626,257,208,2734,649,1886,2391,1695,246,2447,2811,1378,1703,1617,260,1567,1424,654,1516,2647,415,2863,2451 | 0.2499026019446144,-0.29131079005371857,0.37323082292864296,-0.16537868346442086,0.18802891238331532,0.4755894045159319,-0.20728341801373437,-0.845166484742484,0.352714297145243,-0.06092655176681376,1.1824164060489466,0.14670037120281113,-0.9100071940702691,2.0501568052051606,2.0891147678360613,-0.01926704960112091,-0.587809634186986,0.2292937886448734,1.2223321368163933,0.2910734677256283,7.077162194942315,-0.14445310808685582,-0.12354522852272666,0.5164299238420278,0.352714297145243,0.1673726504047501,-0.12354522852272666,0.06384901323418327,-0.29131079005371857,0.4142187974298949,-0.20728341801373437,1.9134897350999418,-0.5665017880289501,-0.06092655176681376,-0.7160969742146781,-0.29131079005371857,0.18802891238331532,-0.29131079005371857,-0.10265492269446272,0.10530734984835549,0.1673726504047501,-0.587809634186986,0.921762273203752,1.2422720024056197,0.3116357123478239,0.022324505727692668,0.921762273203752,4.53062075988975,1.4013665868313239,-0.22826282947820883,0.4551472654983724,0.12601197226717611,0.08458639893558295,0.3937322929558605,0.6386074394794051,1.0222645998514908,0.4346904255440359,0.921762273203752,1.0824142734467934,-1.01854725430779,0.4142187974298949,-0.22826282947820883,-0.5239474963343811,-0.14445310808685582,0.9620015287859891,-0.5665017880289501,-1.2595390174555432,0.001537164702395684,-0.14445310808685582,-0.10265492269446272,0.921762273203752,-0.08178207009671594,-0.01926704960112091,0.4142187974298949,-0.06092655176681376,-0.8235988933073602,0.6589210414523182,-1.6386272017792467,-0.5665017880289501 | 2,945 |
Contractures of the joints of the upper limbs | 6 | 58 | 2.771287 | 0.005584 | Q15392,Q99720,P37268,O75844,Q9Y619,Q96AY3 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 5,8,12,80,50,19 | 1706,1791,2400,682,2258,80,1008,2453,790,1245,402,706,2372,2127,1477,1630,2094,2058,115,12,264,2520,2436,315,982,1910,712,2722,404,1146,774,2381,1067,1724,2610,1316,5,1920,1447,2817,2278,959,625,1227,1452,19,208,1034,8,2712,2745,1777,787,445,1241,2480,50,1520 | -0.16537868346442086,-0.20728341801373437,-0.5452144624387532,0.37323082292864296,-0.4390800866390325,2.0501568052051606,0.1673726504047501,-0.587809634186986,0.2910734677256283,0.04309508514240472,0.6589210414523182,0.352714297145243,-0.5239474963343811,-0.35452613486786577,-0.06092655176681376,-0.12354522852272666,-0.33343552863307785,-0.31236379292464844,1.618928329270631,4.770037134790452,0.9016232814114782,-0.6518579433658428,-0.5665017880289501,0.8007319209650764,0.18802891238331532,-0.2492604414061187,0.352714297145243,-0.9967910215997426,0.6589210414523182,0.10530734984835549,0.3116357123478239,-0.5239474963343811,0.14670037120281113,-0.16537868346442086,-0.7590312945413134,0.022324505727692668,5.735788324107087,-0.2492604414061187,-0.04008825025596049,-1.3037005802478918,-0.4390800866390325,0.20866925843125922,0.4346904255440359,0.06384901323418327,-0.04008825025596049,4.34572728753516,1.0824142734467934,0.1673726504047501,5.500372154885624,-0.9533513246189271,-1.0621336151647116,-0.18632207833549766,0.3116357123478239,0.6182798801100748,0.06384901323418327,-0.587809634186986,2.592105567404909,-0.06092655176681376 | 2,945 |
Cellular modified amino acid metabolic process | 7 | 51 | 2.767889 | 0.005642 | P00374,O60725,Q8NCC3,P11310,Q9UHG3,Q9BZF1,P78417 | Processes and pathways | GO Biological process | msigdb_gobp | 1,6,7,11,20,118,150 | 2162,2572,6,595,1949,2315,1,1529,2454,2690,2631,11,1852,2090,2260,2498,185,402,2846,2175,1477,1098,2820,1299,708,976,2100,2504,1587,2436,2635,1099,1139,2869,150,2636,1966,1107,1268,460,7,1223,2565,2682,888,118,1696,813,630,20,2423 | -0.37563575123099097,-0.7160969742146781,5.699629863835562,0.4551472654983724,-0.2702763842063141,-0.4814740099977851,7.448017023011698,-0.08178207009671594,-0.587809634186986,-0.9100071940702691,-0.8020539598800626,4.9168542761704375,-0.22826282947820883,-0.33343552863307785,-0.4390800866390325,-0.6304875446399937,1.142452277500605,0.6589210414523182,-1.5262302338877283,-0.37563575123099097,-0.06092655176681376,0.12601197226717611,-1.3479736939343891,0.022324505727692668,0.352714297145243,0.18802891238331532,-0.33343552863307785,-0.6304875446399937,-0.10265492269446272,-0.5665017880289501,-0.8020539598800626,0.12601197226717611,0.10530734984835549,-1.7064250666788545,1.2821160279306807,-0.8020539598800626,-0.2702763842063141,0.12601197226717611,0.04309508514240472,0.597938284242163,5.6091396582180515,0.06384901323418327,-0.6946624831235061,-0.8883704331508439,0.2499026019446144,1.5992054978277717,-0.14445310808685582,0.2910734677256283,0.4346904255440359,4.1043876915125255,-0.5452144624387532 | 2,945 |
mRNA processing factor | 29 | 71 | 2.75265 | 0.005912 | O75934,Q15233,Q07666,Q16629,Q08170,P19338,Q8WWY3,Q8IWZ8,Q96E39,Q92804,Q12874,Q96PK6,P98179,Q96PU8,P62995,Q07955,Q13242,P23246,Q96SI9,Q14011,Q13595,Q01844,Q9BWF3,P38159,Q15637,P35637,Q15459,Q9Y4C8,O75494 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 374,517,273,407,163,532,432,566,173,180,562,188,61,330,197,324,77,333,212,93,346,226,239,109,363,115,518,527,127 | 969,576,2648,1382,1793,127,1125,374,1387,2428,1527,930,1092,863,1167,532,333,2096,115,109,766,1680,1142,2793,1440,2663,197,871,61,226,273,324,163,872,1494,1100,562,1171,1442,77,2139,717,346,93,1725,517,1766,518,363,2069,407,1873,566,1686,2693,432,722,180,173,1882,694,1326,188,330,212,239,2334,2870,2192,527,2812 | 0.18802891238331532,0.4755894045159319,-0.845166484742484,-0.01926704960112091,-0.20728341801373437,1.4806368149043725,0.10530734984835549,0.6995066854647584,-0.01926704960112091,-0.5665017880289501,-0.08178207009671594,0.20866925843125922,0.12601197226717611,0.2499026019446144,0.08458639893558295,0.5164299238420278,0.7602824013383189,-0.33343552863307785,1.618928329270631,1.6780316249499048,0.3116357123478239,-0.14445310808685582,0.10530734984835549,-1.2154867397644784,-0.04008825025596049,-0.8667569312531026,1.1224519125778383,0.2499026019446144,2.399390495804993,1.0222645998514908,0.8814712891547717,0.7805138743060999,1.2422720024056197,0.2499026019446144,-0.06092655176681376,0.12601197226717611,0.49601692885848886,0.08458639893558295,-0.04008825025596049,2.0891147678360613,-0.35452613486786577,0.352714297145243,0.7400374285311478,1.8939254041622147,-0.16537868346442086,0.5368284738518867,-0.18632207833549766,0.5368284738518867,0.7197788815940095,-0.31236379292464844,0.6589210414523182,-0.22826282947820883,0.49601692885848886,-0.14445310808685582,-0.9100071940702691,0.6386074394794051,0.352714297145243,1.1824164060489466,1.202380291141655,-0.22826282947820883,0.37323082292864296,0.022324505727692668,1.142452277500605,0.7805138743060999,1.062376874281129,0.9821019275934442,-0.4814740099977851,-1.7064250666788545,-0.37563575123099097,0.5368284738518867,-1.2595390174555432 | 2,945 |
Abnormality of hepatobiliary system physiology | 10 | 75 | 2.743941 | 0.006071 | P03886,O43772,O15460,Q9H845,P11310,Q8TCJ2,P00846,Q9Y619,Q6NUQ1,Q8N511 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 2,34,100,70,11,111,18,50,28,30 | 1193,1336,100,1945,34,1946,1995,373,2630,2855,825,1527,18,739,2,2746,763,1014,1951,826,11,2727,1628,828,420,1477,2558,1803,272,1673,2238,2939,1019,1714,1808,1908,1056,2869,1355,1960,1021,2377,2321,1963,1443,2929,688,2637,348,1028,138,2782,28,691,1644,30,111,806,1228,785,649,70,2532,2115,1419,1655,1779,1119,892,923,654,1516,1659,482,50 | 0.06384901323418327,0.001537164702395684,1.7763226939226555,-0.2702763842063141,3.392192755458683,-0.2702763842063141,-0.29131079005371857,0.6995066854647584,-0.8020539598800626,-1.5935772487808675,0.27049579609526114,-0.08178207009671594,4.364245678303629,0.33218262437609547,7.077162194942315,-1.0839642060391366,0.3116357123478239,0.1673726504047501,-0.2702763842063141,0.27049579609526114,4.9168542761704375,-1.01854725430779,-0.12354522852272666,0.27049579609526114,0.6386074394794051,-0.06092655176681376,-0.6946624831235061,-0.20728341801373437,0.8814712891547717,-0.14445310808685582,-0.417912582552414,-5.399061502057131,0.1673726504047501,-0.16537868346442086,-0.20728341801373437,-0.2492604414061187,0.14670037120281113,-1.7064250666788545,0.001537164702395684,-0.2702763842063141,0.1673726504047501,-0.5239474963343811,-0.4814740099977851,-0.2702763842063141,-0.04008825025596049,-3.571580495971794,0.37323082292864296,-0.8020539598800626,0.7400374285311478,0.1673726504047501,1.3815204900608,-1.1715415663081576,3.6745672923672013,0.37323082292864296,-0.12354522852272666,3.6182258797931914,1.6780316249499048,0.2910734677256283,0.06384901323418327,0.3116357123478239,0.4142187974298949,2.2057541946060866,-0.6518579433658428,-0.33343552863307785,-0.01926704960112091,-0.12354522852272666,-0.18632207833549766,0.12601197226717611,0.2499026019446144,0.2292937886448734,0.4142187974298949,-0.06092655176681376,-0.12354522852272666,0.5775825719273033,2.592105567404909 | 2,945 |
Secondary alcohol metabolic process | 8 | 40 | 2.733718 | 0.006262 | Q8WTV0,Q15392,Q16850,P35610,P37268,Q9BQE5,P48449,Q14739 | Processes and pathways | GO Biological process | msigdb_gobp | 32,5,101,107,12,51,91,29 | 1336,1468,825,595,1008,2719,2773,2746,1852,2235,402,2237,512,107,12,1202,91,145,1137,2580,1059,1485,2826,1359,2063,405,2524,1313,29,1867,2350,5,2653,2847,101,32,2778,51,2628,435 | 0.001537164702395684,-0.06092655176681376,0.27049579609526114,0.4551472654983724,0.1673726504047501,-0.9967910215997426,-1.1496084842326584,-1.0839642060391366,-0.22826282947820883,-0.417912582552414,0.6589210414523182,-0.417912582552414,0.5368284738518867,1.7173799770740772,4.770037134790452,0.06384901323418327,1.9134897350999418,1.321912831571934,0.10530734984835549,-0.7160969742146781,0.14670037120281113,-0.06092655176681376,-1.3701528148541127,0.001537164702395684,-0.31236379292464844,0.6589210414523182,-0.6518579433658428,0.022324505727692668,3.655794126757704,-0.22826282947820883,-0.5027007309924332,5.735788324107087,-0.845166484742484,-1.5262302338877283,1.7763226939226555,3.5053441140537633,-1.1496084842326584,2.5151278038931033,-0.7805314905603624,0.6386074394794051 | 2,945 |
Runx1 regulates transcription of genes involved in differentiation of hscs | 6 | 41 | 2.7126 | 0.006676 | P25787,P60900,P28072,Q03164,P20618,P28070 | Processes and pathways | Reactome Pathways | msigdb_reactome | 3,196,69,13,261,31 | 550,2398,2163,1523,1337,1622,1532,1672,261,1249,3,1533,2483,1631,31,69,829,2318,1809,2578,2505,469,561,1306,196,580,1863,1638,1595,1488,13,2244,1210,283,2750,1265,2279,504,1114,1237,1568 | 0.49601692885848886,-0.5452144624387532,-0.37563575123099097,-0.08178207009671594,0.001537164702395684,-0.12354522852272666,-0.08178207009671594,-0.14445310808685582,0.9016232814114782,0.04309508514240472,6.86435802761024,-0.08178207009671594,-0.609138164405286,-0.12354522852272666,3.5053441140537633,2.2639439873853995,0.27049579609526114,-0.4814740099977851,-0.20728341801373437,-0.7160969742146781,-0.6304875446399937,0.5775825719273033,0.49601692885848886,0.022324505727692668,1.1224519125778383,0.4755894045159319,-0.22826282947820883,-0.12354522852272666,-0.10265492269446272,-0.06092655176681376,4.659667932546476,-0.417912582552414,0.06384901323418327,0.8613062272321225,-1.0839642060391366,0.04309508514240472,-0.4390800866390325,0.5572126623575777,0.12601197226717611,0.06384901323418327,-0.08178207009671594 | 2,945 |
Proteasome degradation | 13 | 42 | 2.704559 | 0.00684 | P49721,P04843,P25787,P60900,P28072,Q99436,P20618,P10321,P04439,P51665,O00231,P46934,P28070 | Processes and pathways | WikiPathways | msigdb_wp | 469,184,3,196,69,504,261,419,175,561,550,558,31 | 550,2398,1523,1337,1622,739,175,184,791,419,1532,1672,261,2127,1249,3,1533,2483,1631,31,69,829,2318,1809,558,2578,2505,469,561,1306,196,580,1863,1638,1595,2244,1210,1265,504,1114,1237,1568 | 0.49601692885848886,-0.5452144624387532,-0.08178207009671594,0.001537164702395684,-0.12354522852272666,0.33218262437609547,1.1824164060489466,1.142452277500605,0.2910734677256283,0.6386074394794051,-0.08178207009671594,-0.14445310808685582,0.9016232814114782,-0.35452613486786577,0.04309508514240472,6.86435802761024,-0.08178207009671594,-0.609138164405286,-0.12354522852272666,3.5053441140537633,2.2639439873853995,0.27049579609526114,-0.4814740099977851,-0.20728341801373437,0.49601692885848886,-0.7160969742146781,-0.6304875446399937,0.5775825719273033,0.49601692885848886,0.022324505727692668,1.1224519125778383,0.4755894045159319,-0.22826282947820883,-0.12354522852272666,-0.10265492269446272,-0.417912582552414,0.06384901323418327,0.04309508514240472,0.5572126623575777,0.12601197226717611,0.06384901323418327,-0.08178207009671594 | 2,945 |
FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179] | 6 | 11 | 2.692879 | 0.007084 | Q9Y680,Q96AY3,Q13451,P62942,Q02790,Q9NWM8 | Sequence | InterPro Domain | interpro_domain | 98,19,83,25,58,59 | 1991,1131,25,801,58,83,1866,219,19,59,98 | -0.29131079005371857,0.10530734984835549,3.768324465880385,0.2910734677256283,2.438006058944413,1.9916454712619938,-0.22826282947820883,1.0423270044122548,4.34572728753516,2.438006058944413,1.835170758534991 | 2,945 |
Endoplasmic reticulum | 71 | 463 | 2.676898 | 0.007431 | Q12768,P07099,Q15392,O60725,Q99720,Q32P28,Q15293,P37268,Q9NYU2,Q9UBF8,Q96AY3,Q04656,Q9NZ08,Q969N2,P62942,O95881,Q14257,Q6NUQ1,Q14739,Q8N511,Q9H3N1,P35613,Q9BUN8,P80303,Q9Y282,O43390,Q01105,Q5JRA6,Q86XL3,Q9UQB8,O43852,P04439,P84157,Q9BQE5,Q92643,P13674,Q9NWM8,O95456,P04843,P24390,P43307,Q96G23,O00264,Q8NHP6,Q8NFQ8,O76024,Q8IXB1,O75844,Q86UE4,Q6UWP7,O60506,P48449,Q92791,P30519,Q9Y680,O15460,Q16850,Q9UMX5,P49257,Q07065,P35610,Q8N0U8,Q8TCJ2,O15173,O15027,O15260,Q9BS26,Q9H2M9,Q9BZF1,Q13217,Q12907 | Localization | GO Cellular component | msigdb_gocc | 130,4,5,6,8,136,139,12,143,16,19,148,22,152,25,149,26,28,29,30,159,161,38,40,41,169,170,172,46,47,48,175,177,51,52,176,59,60,184,64,68,72,192,73,74,76,206,80,81,211,215,91,92,96,98,100,101,103,231,233,107,110,111,237,236,114,245,246,118,241,123 | 300,2784,1193,1990,735,192,446,678,819,1427,2926,467,1664,236,1336,237,2552,114,1788,1286,1789,100,2086,509,2164,2426,169,510,2367,1159,2772,48,1794,2313,215,6,1049,551,2890,1288,1124,1161,2088,2928,2052,388,2855,80,825,1949,76,2341,2713,859,417,1008,553,1196,762,2856,1164,2169,60,899,1580,2786,1848,1010,738,149,1905,2053,2719,739,2773,2746,175,1668,184,791,1090,2792,929,4,418,659,1472,2259,1093,419,2708,2602,2575,1851,344,176,390,2055,468,402,683,1343,1296,1854,1297,1712,2500,1347,1016,2127,2592,579,64,934,2176,1098,1131,2604,2177,2206,1630,2557,707,423,2820,2094,2129,334,534,740,96,2868,2056,2207,2095,741,1133,1393,107,161,2209,12,1019,1674,1859,68,2345,2458,2131,1394,979,91,2436,867,1634,1811,2240,231,2179,903,315,904,1482,1395,939,597,868,2009,1303,1483,1354,2347,2438,2319,769,1679,1960,1636,1816,2210,2728,2103,2775,2010,1862,323,1258,1758,2011,2135,1024,2581,2826,942,581,1594,2379,1206,2303,1489,2673,1207,25,1864,2015,1760,2408,40,2016,1640,1209,177,2561,1063,170,1026,404,1820,2064,451,2776,148,2273,233,2460,908,2065,130,642,1723,1641,123,715,2888,583,2737,241,2929,473,2710,2562,873,2931,26,1866,1313,688,29,1867,1211,1495,2544,2837,1316,1175,951,139,623,2923,5,2247,1148,1683,1869,988,2653,2847,2582,2935,101,2677,136,1728,2835,275,2526,172,1685,1214,1496,1072,28,953,2788,1364,2111,211,1497,1971,585,1556,2143,296,520,81,498,46,2704,2655,2583,2679,957,206,645,110,287,364,460,2744,30,1183,745,989,337,646,2465,958,746,2511,2145,74,2769,73,1222,2875,2466,111,806,2739,624,1732,353,1150,522,625,2279,2029,1411,52,1321,92,1879,1502,152,381,1452,1228,2715,1880,2716,19,1229,2764,540,72,2732,586,1372,1153,1736,433,394,2513,1272,886,2389,2586,2682,887,607,8,888,1274,2894,51,245,1839,2930,649,2712,2472,723,38,2853,2879,2418,118,725,369,650,1842,2360,246,159,571,2587,2696,1740,697,2531,2822,2754,2473,1417,2193,253,2942,628,753,2810,2919,2255,2550,1932,2475,2836,2613,59,2286,1082,143,1280,22,1890,1422,1119,341,610,16,2628,2902,270,2040,2394,2154,2199,789,758,2336,103,1424,1743,342,47,2363,41,655,414,1466,2854,2396,2450,2804,2084,291,2647,2881,2863,371,590,98,1519,818 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Negative regulation of rna catabolic process | 16 | 32 | 2.661651 | 0.007776 | P11940,P67809,Q08J23,Q9H2U1,P98175,Q92804,Q9GZT3,Q13151,Q99729,P35637,Q06787,Q14103,O60506,Q9H814,Q14011,P07910 | Processes and pathways | GO Biological process | msigdb_gobp | 660,129,392,695,515,180,146,563,209,115,254,335,215,478,93,401 | 1193,215,1995,1384,1527,401,660,115,1056,980,129,515,1722,254,1492,392,2018,563,93,335,988,1027,1030,1878,180,209,146,812,695,478,1002,733 | 0.06384901323418327,1.0423270044122548,-0.29131079005371857,-0.01926704960112091,-0.08178207009671594,0.6589210414523182,0.3937322929558605,1.618928329270631,0.14670037120281113,0.18802891238331532,1.4410244250244986,0.5368284738518867,-0.16537868346442086,0.921762273203752,-0.06092655176681376,0.6792207642978566,-0.29131079005371857,0.49601692885848886,1.8939254041622147,0.7602824013383189,0.18802891238331532,0.1673726504047501,0.1673726504047501,-0.22826282947820883,1.1824164060489466,1.0824142734467934,1.321912831571934,0.2910734677256283,0.37323082292864296,0.5775825719273033,0.18802891238331532,0.352714297145243 | 2,945 |
Polymicrogyria | 15 | 68 | 2.653301 | 0.007971 | Q16625,Q9UMX1,Q15392,P55011,Q96N66,Q01105,Q08J23,Q9Y487,P37268,O43505,P21281,Q9H2M9,Q8TD16,Q96EK5,Q9UBB6 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 348,260,5,232,394,170,392,140,12,200,105,246,87,409,356 | 1706,1791,200,528,2630,1246,1014,1849,1094,1054,1855,105,1477,976,1806,1252,796,12,1018,1714,1859,1860,1715,1677,2539,982,1593,232,1864,2104,944,170,1962,392,1963,1065,1641,1146,774,2563,2610,1316,5,2653,348,2729,428,1971,1111,87,2584,409,1835,1559,394,1187,246,2754,628,2224,1280,356,260,1567,1466,140,1335,2451 | -0.16537868346442086,-0.20728341801373437,1.1024392652871489,0.5164299238420278,-0.8020539598800626,0.04309508514240472,0.1673726504047501,-0.22826282947820883,0.12601197226717611,0.14670037120281113,-0.22826282947820883,1.7370381436593936,-0.06092655176681376,0.18802891238331532,-0.20728341801373437,0.04309508514240472,0.2910734677256283,4.770037134790452,0.1673726504047501,-0.16537868346442086,-0.22826282947820883,-0.22826282947820883,-0.16537868346442086,-0.14445310808685582,-0.6732495316326513,0.18802891238331532,-0.10265492269446272,1.0021895959906988,-0.22826282947820883,-0.33343552863307785,0.20866925843125922,1.202380291141655,-0.2702763842063141,0.6792207642978566,-0.2702763842063141,0.14670037120281113,-0.12354522852272666,0.10530734984835549,0.3116357123478239,-0.6946624831235061,-0.7590312945413134,0.022324505727692668,5.735788324107087,-0.845166484742484,0.7400374285311478,-1.01854725430779,0.6386074394794051,-0.2702763842063141,0.12601197226717611,1.9525878342172756,-0.7160969742146781,0.6589210414523182,-0.20728341801373437,-0.08178207009671594,0.6792207642978566,0.08458639893558295,0.9620015287859891,-1.0839642060391366,0.4346904255440359,-0.3967645192768137,0.04309508514240472,0.7400374285311478,0.921762273203752,-0.08178207009671594,-0.04008825025596049,1.3616628687817531,0.022324505727692668,-0.5665017880289501 | 2,945 |
Response to wounding | 12 | 75 | 2.644677 | 0.008177 | Q8WTV0,P00374,O00330,P49257,Q96G23,P55011,Q5JRA6,Q96AY3,Q04656,P32119,Q05397,P42785 | Processes and pathways | GO Biological process | msigdb_gobp | 32,1,193,231,72,232,172,19,148,210,217,27 | 1194,1426,2162,193,701,822,761,1,862,2690,2906,1091,929,1052,1292,2259,249,1851,792,2236,1130,2372,827,2868,210,866,742,1859,1675,27,2099,1715,231,232,941,2300,2135,1864,2348,1026,451,148,217,2460,717,2215,1172,1763,2019,1264,2674,2638,666,1027,348,2248,172,913,32,2187,1503,19,540,72,2148,2332,477,725,385,1421,1233,730,700,1121,1896 | 0.06384901323418327,-0.04008825025596049,-0.37563575123099097,1.1224519125778383,0.352714297145243,0.27049579609526114,0.3116357123478239,7.448017023011698,0.2499026019446144,-0.9100071940702691,-2.23448571265435,0.12601197226717611,0.20866925843125922,0.14670037120281113,0.022324505727692668,-0.4390800866390325,0.9418883330481125,-0.22826282947820883,0.2910734677256283,-0.417912582552414,0.10530734984835549,-0.5239474963343811,0.27049579609526114,-1.7064250666788545,1.062376874281129,0.2499026019446144,0.33218262437609547,-0.22826282947820883,-0.14445310808685582,3.6745672923672013,-0.33343552863307785,-0.16537868346442086,1.0021895959906988,1.0021895959906988,0.20866925843125922,-0.4602671791946553,-0.35452613486786577,-0.22826282947820883,-0.5027007309924332,0.1673726504047501,0.597938284242163,1.3020203038267055,1.0423270044122548,-0.587809634186986,0.352714297145243,-0.3967645192768137,0.08458639893558295,-0.18632207833549766,-0.29131079005371857,0.04309508514240472,-0.8883704331508439,-0.8020539598800626,0.3937322929558605,0.1673726504047501,0.7400374285311478,-0.417912582552414,1.202380291141655,0.2292937886448734,3.5053441140537633,-0.37563575123099097,-0.06092655176681376,4.34572728753516,0.5164299238420278,2.166913142114243,-0.35452613486786577,-0.4814740099977851,0.5775825719273033,0.352714297145243,0.6995066854647584,-0.01926704960112091,0.06384901323418327,0.352714297145243,0.37323082292864296,0.12601197226717611,-0.22826282947820883 | 2,945 |
Pain | 35 | 165 | 2.640347 | 0.008282 | Q15165,Q969G3,Q9UMX1,Q9UGP8,Q70HW3,P11310,P42892,P48735,P35670,P00846,Q04656,Q15043,Q9NZ08,Q969N2,Q14739,P28070,Q07864,Q92804,O60313,P50402,Q8NFH4,Q8N1F7,Q9H845,O75844,Q8TAA9,Q14566,O15460,Q01844,P22626,Q13423,P35637,P21912,Q6UN15,Q06787,Q15056 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 0,257,260,270,10,11,264,145,272,18,148,151,22,152,29,31,162,180,174,315,320,327,70,80,221,227,100,226,224,112,115,119,125,254,255 | 1991,678,1706,701,1788,1286,100,680,702,174,1125,2165,80,595,973,1164,1011,1905,2574,2123,18,739,790,2746,2591,1668,2767,763,2932,2844,2482,1470,1014,2231,359,530,2343,11,1852,2456,2913,390,706,1854,662,827,119,1391,1346,2127,487,224,1628,1477,533,707,31,1750,2057,2001,641,115,272,2002,1955,1134,2486,1808,937,264,424,902,145,1716,1137,315,1058,711,2181,2887,490,1756,2438,2270,769,1910,1679,1960,712,2062,2010,1143,440,226,2017,452,405,148,2459,254,162,1913,2066,1443,2018,1360,112,2929,1066,2381,2931,718,1965,227,688,29,1314,950,151,255,0,2676,2847,2643,2760,2110,125,10,1074,2936,327,1646,320,221,959,1604,2564,625,1689,180,1879,257,152,1649,1372,2712,2076,1415,1375,70,2754,1929,755,22,2599,757,270,1934,1617,260,342,700,732,2647,1379 | -0.29131079005371857,0.37323082292864296,-0.16537868346442086,0.352714297145243,-0.20728341801373437,0.022324505727692668,1.7763226939226555,0.37323082292864296,0.352714297145243,1.1824164060489466,0.10530734984835549,-0.37563575123099097,2.0501568052051606,0.4551472654983724,0.18802891238331532,0.08458639893558295,0.1673726504047501,-0.2492604414061187,-0.7160969742146781,-0.35452613486786577,4.364245678303629,0.33218262437609547,0.2910734677256283,-1.0839642060391366,-0.7375531840373677,-0.14445310808685582,-1.1277013965550577,0.3116357123478239,-3.890742390654541,-1.5038429397324582,-0.609138164405286,-0.06092655176681376,0.1673726504047501,-0.417912582552414,0.7197788815940095,0.5164299238420278,-0.5027007309924332,4.9168542761704375,-0.22826282947820883,-0.587809634186986,-2.586040646525843,0.6792207642978566,0.352714297145243,-0.22826282947820883,0.3937322929558605,0.27049579609526114,1.5794717175274886,-0.01926704960112091,0.001537164702395684,-0.35452613486786577,0.5572126623575777,1.0222645998514908,-0.12354522852272666,-0.06092655176681376,0.5164299238420278,0.352714297145243,3.5053441140537633,-0.18632207833549766,-0.31236379292464844,-0.29131079005371857,0.4142187974298949,1.618928329270631,0.8814712891547717,-0.29131079005371857,-0.2702763842063141,0.10530734984835549,-0.609138164405286,-0.20728341801373437,0.20866925843125922,0.9016232814114782,0.6386074394794051,0.2292937886448734,1.321912831571934,-0.16537868346442086,0.10530734984835549,0.8007319209650764,0.14670037120281113,0.352714297145243,-0.37563575123099097,-1.9113655148381163,0.5572126623575777,-0.18632207833549766,-0.5665017880289501,-0.4390800866390325,0.3116357123478239,-0.2492604414061187,-0.14445310808685582,-0.2702763842063141,0.352714297145243,-0.31236379292464844,-0.29131079005371857,0.10530734984835549,0.6182798801100748,1.0222645998514908,-0.29131079005371857,0.597938284242163,0.6589210414523182,1.3020203038267055,-0.587809634186986,0.921762273203752,1.2422720024056197,-0.2492604414061187,-0.31236379292464844,-0.04008825025596049,-0.29131079005371857,0.001537164702395684,1.6583413438014383,-3.571580495971794,0.14670037120281113,-0.5239474963343811,-3.8168269043326535,0.352714297145243,-0.2702763842063141,1.0222645998514908,0.37323082292864296,3.655794126757704,0.022324505727692668,0.20866925843125922,1.2821160279306807,0.921762273203752,7.623940234694683,-0.8883704331508439,-1.5262302338877283,-0.8235988933073602,-1.105820052560868,-0.33343552863307785,1.5004260995112062,5.045004847981975,0.14670037120281113,-4.537593048427522,0.7805138743060999,-0.12354522852272666,0.8007319209650764,1.0423270044122548,0.20866925843125922,-0.10265492269446272,-0.6946624831235061,0.4346904255440359,-0.14445310808685582,1.1824164060489466,-0.22826282947820883,0.921762273203752,1.2821160279306807,-0.12354522852272666,0.001537164702395684,-0.9533513246189271,-0.31236379292464844,-0.01926704960112091,0.001537164702395684,2.2057541946060866,-1.0839642060391366,-0.2492604414061187,0.33218262437609547,3.824492664661767,-0.7375531840373677,0.33218262437609547,0.9016232814114782,-0.2492604414061187,-0.10265492269446272,0.921762273203752,0.7602824013383189,0.37323082292864296,0.352714297145243,-0.8235988933073602,0.001537164702395684 | 2,945 |
Dehydrogenase | 10 | 52 | 2.637245 | 0.008358 | P03886,P05091,Q9BY49,Q8N8N7,Q8N4Q0,Q13423,O94788,Q96CU9,P30837,O95831 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 2,67,37,75,44,112,49,113,55,89 | 1791,1468,1577,373,49,89,2574,2053,1529,2,2228,67,2342,2556,826,1852,2576,185,119,2093,2129,55,1750,2208,2005,2486,557,2635,1099,2580,1592,2269,1909,1355,1910,1819,907,112,2873,1870,1967,2330,44,75,2466,113,2074,37,2570,1280,2940,2197 | -0.20728341801373437,-0.06092655176681376,-0.10265492269446272,0.6995066854647584,2.6113277676568396,1.9330438639514882,-0.7160969742146781,-0.31236379292464844,-0.08178207009671594,7.077162194942315,-0.417912582552414,2.341397984173776,-0.5027007309924332,-0.6946624831235061,0.27049579609526114,-0.22826282947820883,-0.7160969742146781,1.142452277500605,1.5794717175274886,-0.33343552863307785,-0.35452613486786577,2.4573001148610345,-0.18632207833549766,-0.3967645192768137,-0.29131079005371857,-0.609138164405286,0.49601692885848886,-0.8020539598800626,0.12601197226717611,-0.7160969742146781,-0.10265492269446272,-0.4390800866390325,-0.2492604414061187,0.001537164702395684,-0.2492604414061187,-0.20728341801373437,0.2292937886448734,1.6583413438014383,-1.751769488181549,-0.22826282947820883,-0.2702763842063141,-0.4814740099977851,2.860424771989179,2.1085789946182025,-0.587809634186986,1.6386402615157454,-0.31236379292464844,3.2408955872793364,-0.6946624831235061,0.04309508514240472,-5.9391553365988985,-0.37563575123099097 | 2,945 |
Cellular response to hormone stimulus | 37 | 117 | 2.625924 | 0.008641 | Q9HCD5,P31751,Q9H7B4,Q15043,Q8WWQ0,Q8TDD1,Q6ZWJ1,P42785,P16435,P25054,O75116,Q92922,P43490,Q9NS86,Q9UQB8,Q13547,O60763,Q02790,O94813,P20020,P46934,P61026,P61960,Q9H270,O95831,Q7L576,Q05397,Q9H1E3,Q8IZL8,P42224,O15173,P61981,P35241,Q9BZF1,P22413,P62993,Q9GZZ9 | Processes and pathways | GO Biological process | msigdb_gobp | 269,262,14,151,672,671,669,27,402,533,400,568,43,305,47,54,551,58,552,314,558,323,581,339,89,604,217,354,352,238,237,620,618,118,487,491,650 | 2288,1662,820,1047,1336,237,1123,1794,2650,703,551,400,552,859,1579,89,862,1090,2600,1470,2229,1342,1093,1294,2202,2055,1129,402,2172,933,1296,314,487,533,1435,2557,707,262,2095,977,618,1134,936,238,27,43,2099,1715,558,2100,2504,1591,1539,2521,905,1485,2377,2721,323,2135,581,620,1596,491,2104,1598,1721,1722,58,1491,2607,217,2459,2066,2859,987,2139,2216,1262,54,2245,151,2107,1726,1966,1362,666,1028,1364,669,604,1320,352,671,672,1500,1688,918,568,2030,994,1370,1372,2682,2332,118,650,354,339,965,14,2447,269,305,1461,47,2159 | -0.4602671791946553,-0.14445310808685582,0.27049579609526114,0.14670037120281113,0.001537164702395684,0.9821019275934442,0.10530734984835549,-0.20728341801373437,-0.845166484742484,0.352714297145243,0.49601692885848886,0.6589210414523182,0.49601692885848886,0.2499026019446144,-0.10265492269446272,1.9330438639514882,0.2499026019446144,0.12601197226717611,-0.7590312945413134,-0.06092655176681376,-0.417912582552414,0.001537164702395684,0.12601197226717611,0.022324505727692668,-0.3967645192768137,-0.31236379292464844,0.10530734984835549,0.6589210414523182,-0.37563575123099097,0.20866925843125922,0.022324505727692668,0.8007319209650764,0.5572126623575777,0.5164299238420278,-0.04008825025596049,-0.6946624831235061,0.352714297145243,0.9016232814114782,-0.33343552863307785,0.18802891238331532,0.4346904255440359,0.10530734984835549,0.20866925843125922,0.9821019275934442,3.6745672923672013,2.860424771989179,-0.33343552863307785,-0.16537868346442086,0.49601692885848886,-0.33343552863307785,-0.6304875446399937,-0.10265492269446272,-0.08178207009671594,-0.6518579433658428,0.2292937886448734,-0.06092655176681376,-0.5239474963343811,-0.9967910215997426,0.7805138743060999,-0.35452613486786577,0.4755894045159319,0.4346904255440359,-0.10265492269446272,0.5572126623575777,-0.33343552863307785,-0.10265492269446272,-0.16537868346442086,-0.16537868346442086,2.438006058944413,-0.06092655176681376,-0.7590312945413134,1.0423270044122548,-0.587809634186986,-0.31236379292464844,-1.6386272017792467,0.18802891238331532,-0.35452613486786577,-0.3967645192768137,0.04309508514240472,2.4765850676126675,-0.417912582552414,1.2821160279306807,-0.33343552863307785,-0.16537868346442086,-0.2702763842063141,0.001537164702395684,0.3937322929558605,0.1673726504047501,0.001537164702395684,0.3937322929558605,0.4551472654983724,0.022324505727692668,0.7400374285311478,0.3937322929558605,0.3937322929558605,-0.06092655176681376,-0.14445310808685582,0.2292937886448734,0.49601692885848886,-0.29131079005371857,0.18802891238331532,0.001537164702395684,0.001537164702395684,-0.8883704331508439,-0.4814740099977851,1.5992054978277717,0.4142187974298949,0.7400374285311478,0.7602824013383189,0.20866925843125922,4.62282865259948,-0.5665017880289501,0.9016232814114782,0.8209366140972024,-0.04008825025596049,2.688128608527772,-0.35452613486786577 | 2,945 |
Protein peptidyl prolyl isomerization | 6 | 23 | 2.61375 | 0.008955 | Q9Y680,Q96AY3,Q13451,P62942,Q02790,Q9NWM8 | Processes and pathways | GO Biological process | msigdb_gobp | 98,19,83,25,58,59 | 1991,1992,2592,1131,2295,1857,2593,1590,25,801,58,2699,83,1147,1866,219,521,19,783,59,1281,613,98 | -0.29131079005371857,-0.29131079005371857,-0.7375531840373677,0.10530734984835549,-0.4602671791946553,-0.22826282947820883,-0.7375531840373677,-0.10265492269446272,3.768324465880385,0.2910734677256283,2.438006058944413,-0.9316674210504035,1.9916454712619938,0.10530734984835549,-0.22826282947820883,1.0423270044122548,0.5368284738518867,4.34572728753516,0.3116357123478239,2.438006058944413,0.04309508514240472,0.4551472654983724,1.835170758534991 | 2,945 |
Contractures of the joints of the lower limbs | 8 | 51 | 2.610699 | 0.009036 | Q99720,P37268,Q86XL3,Q96AY3,O60313,P35637,Q8TD16,P21912 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 8,12,46,19,174,115,87,119 | 193,2400,174,1049,1124,1008,554,790,1245,2125,2236,2372,119,2127,1477,1630,1750,115,1252,12,1134,2060,2436,282,315,1760,985,392,2381,948,2638,2817,46,605,2278,460,806,87,625,1452,19,8,2712,2191,2754,2684,787,1241,2049,1335,2451 | 1.1224519125778383,-0.5452144624387532,1.1824164060489466,0.14670037120281113,0.10530734984835549,0.1673726504047501,0.49601692885848886,0.2910734677256283,0.04309508514240472,-0.35452613486786577,-0.417912582552414,-0.5239474963343811,1.5794717175274886,-0.35452613486786577,-0.06092655176681376,-0.12354522852272666,-0.18632207833549766,1.618928329270631,0.04309508514240472,4.770037134790452,0.10530734984835549,-0.31236379292464844,-0.5665017880289501,0.8613062272321225,0.8007319209650764,-0.18632207833549766,0.18802891238331532,0.6792207642978566,-0.5239474963343811,0.20866925843125922,-0.8020539598800626,-1.3037005802478918,2.841314827134973,0.4551472654983724,-0.4390800866390325,0.597938284242163,0.2910734677256283,1.9525878342172756,0.4346904255440359,-0.04008825025596049,4.34572728753516,5.500372154885624,-0.9533513246189271,-0.37563575123099097,-1.0839642060391366,-0.8883704331508439,0.3116357123478239,0.06384901323418327,-0.29131079005371857,0.022324505727692668,-0.5665017880289501 | 2,945 |
Negative regulation of mrna processing | 11 | 20 | 2.608071 | 0.009105 | Q08170,P61978,P22626,Q6PJT7,Q13242,Q07021,P98175,P38159,O75150,Q16629,O75494 | Processes and pathways | GO Biological process | msigdb_gobp | 163,134,224,428,77,178,515,109,484,407,127 | 968,1786,484,127,1345,224,2092,1392,109,134,515,178,163,1100,77,717,407,644,565,428 | 0.18802891238331532,-0.20728341801373437,0.5572126623575777,1.4806368149043725,0.001537164702395684,1.0222645998514908,-0.33343552863307785,-0.01926704960112091,1.6780316249499048,1.4212012137589964,0.5368284738518867,1.1824164060489466,1.2422720024056197,0.12601197226717611,2.0891147678360613,0.352714297145243,0.6589210414523182,0.4142187974298949,0.49601692885848886,0.6386074394794051 | 2,945 |
Muscle weakness | 40 | 271 | 2.604201 | 0.009209 | Q15165,P00374,P03886,Q12768,Q969G3,P61978,Q9UMX1,O14979,Q99720,Q4J6C6,Q70HW3,P11310,P35270,P35670,P00846,Q04656,Q15043,Q86U42,Q14739,O43772,Q13126,P00403,Q92804,O60313,Q9NWM8,O96000,Q9H845,O43505,Q8TD16,O95831,Q8N9N2,O15460,P22626,Q96CU9,Q96F07,P35637,P21912,Q8N0X7,Q6UN15,Q06787 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 0,1,2,130,257,134,260,132,8,137,10,11,271,272,18,148,151,276,29,34,35,166,180,174,59,63,70,200,87,89,220,100,224,113,243,115,119,251,125,254 | 852,446,1522,1944,1706,2851,701,132,1788,1286,100,200,2918,1159,34,1946,2400,174,2313,594,1577,1288,373,1124,2630,1383,705,1008,973,1164,2791,554,89,63,1,166,2123,18,739,790,2,2591,1089,1668,2906,1090,1669,763,1245,2872,1166,2932,2844,2482,2230,2231,359,2831,530,1582,1851,11,1295,2456,2815,2234,1168,2927,2429,2204,662,827,119,2127,224,1628,2620,1477,2093,1750,1907,935,976,1804,271,1133,115,272,2002,1353,1478,1752,1018,1134,1714,2486,1808,2060,1860,1056,1301,424,2757,2503,2594,2436,1254,2539,1137,1590,2376,315,1058,711,439,1861,2181,982,2132,2887,799,2269,1813,2346,869,2270,1757,1814,1910,1679,1960,1022,2377,2241,2801,2651,134,620,1594,1400,944,1819,404,148,1962,2459,985,254,1963,1065,130,35,2018,1146,2929,2897,2381,718,2563,1965,1402,29,1314,151,2068,602,643,2638,0,517,1362,690,2108,1176,2760,1404,137,2723,350,2920,2729,779,802,721,1826,2782,426,1178,2276,2110,286,125,10,1074,408,276,2794,2936,251,2509,220,2465,2511,670,1646,2666,782,647,1223,806,87,1604,672,625,2680,1321,180,2188,257,1452,2281,113,243,1882,2513,997,2074,8,1693,2189,2734,1327,2712,2075,811,2076,650,1563,70,1376,2754,2684,2755,2285,2224,2361,59,1459,2038,2599,1118,2940,2225,2394,1934,2933,260,342,700,2047,654,1938,2424,2083,1241,1044,482,1335,1940,299,1520 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| 2,945 |
Constitutional symptom | 36 | 216 | 2.60182 | 0.009273 | Q15165,Q969G3,Q12768,Q9UMX1,Q9UGP8,Q99720,Q4J6C6,Q70HW3,P11310,P42892,P48735,P00846,Q04656,Q15043,Q9NZ08,Q969N2,Q14739,P28070,Q07864,Q07021,Q92804,O60313,Q9H845,O75844,Q8TAA9,Q14566,O15460,Q01844,P22626,P35610,Q13423,P35637,P21912,Q6UN15,Q06787,Q15056 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 0,257,130,260,270,8,137,10,11,264,145,18,148,151,22,152,29,31,162,178,180,174,70,80,221,227,100,226,224,107,112,115,119,125,254,255 | 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| 2,945 |
Dna replication pre initiation | 15 | 62 | 2.590093 | 0.009595 | Q14566,Q07864,P25787,P60900,P28072,Q99436,P25205,P20618,Q9Y619,P51665,O00231,Q9NRF9,P35244,P49721,P28070 | Processes and pathways | Reactome Pathways | msigdb_reactome | 227,162,3,196,69,504,422,261,50,561,550,247,438,469,31 | 550,2398,2163,1523,1337,2452,2258,1622,1624,975,1532,1672,261,795,422,1249,3,1533,2483,1799,1631,31,69,829,1251,1713,1352,438,2318,1809,2578,1589,938,2505,469,981,561,2133,1306,196,580,1863,1638,1595,1488,2244,162,1210,1311,227,1211,2750,1265,2279,504,1114,247,1191,1237,1568,2480,50 | 0.49601692885848886,-0.5452144624387532,-0.37563575123099097,-0.08178207009671594,0.001537164702395684,-0.587809634186986,-0.4390800866390325,-0.12354522852272666,-0.12354522852272666,0.18802891238331532,-0.08178207009671594,-0.14445310808685582,0.9016232814114782,0.2910734677256283,0.6386074394794051,0.04309508514240472,6.86435802761024,-0.08178207009671594,-0.609138164405286,-0.20728341801373437,-0.12354522852272666,3.5053441140537633,2.2639439873853995,0.27049579609526114,0.04309508514240472,-0.16537868346442086,0.001537164702395684,0.6182798801100748,-0.4814740099977851,-0.20728341801373437,-0.7160969742146781,-0.10265492269446272,0.20866925843125922,-0.6304875446399937,0.5775825719273033,0.18802891238331532,0.49601692885848886,-0.35452613486786577,0.022324505727692668,1.1224519125778383,0.4755894045159319,-0.22826282947820883,-0.12354522852272666,-0.10265492269446272,-0.06092655176681376,-0.417912582552414,1.2422720024056197,0.06384901323418327,0.022324505727692668,1.0222645998514908,0.06384901323418327,-1.0839642060391366,0.04309508514240472,-0.4390800866390325,0.5572126623575777,0.12601197226717611,0.9620015287859891,0.08458639893558295,0.06384901323418327,-0.08178207009671594,-0.587809634186986,2.592105567404909 | 2,945 |
Methylation | 7 | 87 | 2.564425 | 0.010335 | Q7L592,O60725,Q03164,Q9H7B4,O75844,Q8NB78,Q9BV86 | Processes and pathways | GO Biological process | msigdb_gobp | 65,6,13,14,80,21,62 | 1787,1123,971,2120,702,2650,1085,6,511,1948,80,1578,1290,1165,790,2631,1342,1748,1998,2294,1711,1345,1391,1627,1953,2484,2001,2006,982,2132,2013,2663,1487,13,392,1360,318,946,1101,1173,2610,2867,2275,2644,667,644,565,2384,2328,1407,1644,65,1181,1320,459,2144,1217,443,915,916,21,1922,1227,747,748,674,382,88,477,2074,1775,2741,62,1653,2645,14,1038,396,2626,1457,1613,1003,1933,1004,479,2895,2117 | -0.20728341801373437,0.10530734984835549,0.18802891238331532,-0.35452613486786577,0.352714297145243,-0.845166484742484,0.12601197226717611,5.699629863835562,0.5368284738518867,-0.2702763842063141,2.0501568052051606,-0.10265492269446272,0.022324505727692668,0.08458639893558295,0.2910734677256283,-0.8020539598800626,0.001537164702395684,-0.18632207833549766,-0.29131079005371857,-0.4602671791946553,-0.16537868346442086,0.001537164702395684,-0.01926704960112091,-0.12354522852272666,-0.2702763842063141,-0.609138164405286,-0.29131079005371857,-0.29131079005371857,0.18802891238331532,-0.35452613486786577,-0.29131079005371857,-0.8667569312531026,-0.06092655176681376,4.659667932546476,0.6792207642978566,0.001537164702395684,0.8007319209650764,0.20866925843125922,0.12601197226717611,0.08458639893558295,-0.7590312945413134,-1.6837963753761036,-0.4390800866390325,-0.8235988933073602,0.3937322929558605,0.4142187974298949,0.49601692885848886,-0.5239474963343811,-0.4814740099977851,-0.01926704960112091,-0.12354522852272666,2.3607380919625607,0.08458639893558295,0.022324505727692668,0.597938284242163,-0.35452613486786577,0.06384901323418327,0.6182798801100748,0.2292937886448734,0.2292937886448734,4.01126221185754,-0.2492604414061187,0.06384901323418327,0.33218262437609547,0.33218262437609547,0.3937322929558605,0.6995066854647584,1.9525878342172756,0.5775825719273033,-0.31236379292464844,-0.18632207833549766,-1.0403280423845351,2.399390495804993,-0.12354522852272666,-0.8235988933073602,4.62282865259948,0.1673726504047501,0.6792207642978566,-0.7805314905603624,-0.04008825025596049,-0.10265492269446272,0.18802891238331532,-0.2492604414061187,0.18802891238331532,0.5775825719273033,-1.9801752339439305,-0.33343552863307785 | 2,945 |
Mapk family signaling cascades | 29 | 88 | 2.557548 | 0.010541 | O15020,P25787,O60725,P30086,Q13177,P20618,P62140,Q13813,P28070,P30154,Q9UQ13,P51665,O00231,Q01082,P60900,P28072,P61289,Q9UJF2,Q05397,P49721,Q13555,O43924,Q16181,Q99436,Q9HCE1,Q14168,Q96S59,P30153,P62993 | Processes and pathways | Reactome Pathways | msigdb_reactome | 372,3,6,9,516,261,403,406,31,294,308,561,550,440,196,69,580,357,217,469,473,593,347,504,627,362,244,617,491 | 550,2398,2163,1523,1621,372,1337,593,6,2052,1622,2906,929,1672,1130,261,827,1096,1249,3,1533,2483,2177,1631,31,69,829,2094,9,617,294,830,977,2318,2097,936,1809,1136,2578,765,2505,469,561,1304,1306,196,2103,580,403,1863,1638,1595,491,1864,440,1026,217,2459,2244,516,1210,473,2710,947,406,362,948,2750,1265,623,347,666,2279,2733,244,504,1114,1837,627,755,1002,357,1237,1568,308,893,1896,2903 | 0.49601692885848886,-0.5452144624387532,-0.37563575123099097,-0.08178207009671594,-0.12354522852272666,0.6995066854647584,0.001537164702395684,0.4551472654983724,5.699629863835562,-0.31236379292464844,-0.12354522852272666,-2.23448571265435,0.20866925843125922,-0.14445310808685582,0.10530734984835549,0.9016232814114782,0.27049579609526114,0.12601197226717611,0.04309508514240472,6.86435802761024,-0.08178207009671594,-0.609138164405286,-0.37563575123099097,-0.12354522852272666,3.5053441140537633,2.2639439873853995,0.27049579609526114,-0.33343552863307785,5.445914220137767,0.4346904255440359,0.8411280257469278,0.27049579609526114,0.18802891238331532,-0.4814740099977851,-0.33343552863307785,0.20866925843125922,-0.20728341801373437,0.10530734984835549,-0.7160969742146781,0.3116357123478239,-0.6304875446399937,0.5775825719273033,0.49601692885848886,0.022324505727692668,0.022324505727692668,1.1224519125778383,-0.33343552863307785,0.4755894045159319,0.6589210414523182,-0.22826282947820883,-0.12354522852272666,-0.10265492269446272,0.5572126623575777,-0.22826282947820883,0.6182798801100748,0.1673726504047501,1.0423270044122548,-0.587809634186986,-0.417912582552414,0.5368284738518867,0.06384901323418327,0.5775825719273033,-0.9533513246189271,0.20866925843125922,0.6589210414523182,0.7197788815940095,0.20866925843125922,-1.0839642060391366,0.04309508514240472,0.4346904255440359,0.7400374285311478,0.3937322929558605,-0.4390800866390325,-1.01854725430779,0.9620015287859891,0.5572126623575777,0.12601197226717611,-0.20728341801373437,0.4346904255440359,0.33218262437609547,0.18802891238331532,0.7400374285311478,0.06384901323418327,-0.08178207009671594,0.8209366140972024,0.2499026019446144,-0.22826282947820883,-2.1185069787704807 | 2,945 |
EF-Hand 1, calcium-binding site [IPR018247] | 7 | 36 | 2.550665 | 0.010752 | Q9Y680,P80303,O43852,Q96AY3,P19174,Q14257,Q9NWM8 | Sequence | InterPro Binding site | interpro_binding_site | 98,40,48,19,53,26,59 | 680,48,1124,824,2865,1667,1166,2538,792,2603,390,1343,53,2056,831,557,40,1820,451,406,26,1602,139,2276,2352,2028,19,258,2189,1842,1278,59,2902,2155,730,98 | 0.37323082292864296,2.6113277676568396,0.10530734984835549,0.27049579609526114,-1.661197007707223,-0.14445310808685582,0.08458639893558295,-0.6732495316326513,0.2910734677256283,-0.7590312945413134,0.6792207642978566,0.001537164702395684,2.4765850676126675,-0.31236379292464844,0.27049579609526114,0.49601692885848886,2.91770423556765,-0.20728341801373437,0.597938284242163,0.6589210414523182,3.693333183718309,-0.10265492269446272,1.3616628687817531,-0.4390800866390325,-0.5027007309924332,-0.29131079005371857,4.34572728753516,0.921762273203752,-0.37563575123099097,-0.20728341801373437,0.04309508514240472,2.438006058944413,-2.0722926032580373,-0.35452613486786577,0.352714297145243,1.835170758534991 | 2,945 |
Congenital contracture | 6 | 44 | 2.54444 | 0.010945 | O00330,Q15392,P11310,O75844,Q96AY3,Q8TD16 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 193,5,11,80,19,87 | 193,1791,80,790,2746,1245,11,706,2127,1134,1860,1058,2346,2348,985,1065,1641,2711,2638,5,1362,1553,2729,1970,220,1974,2666,87,1369,1452,1228,1880,19,1034,1693,2075,545,2754,385,1082,574,1938,2451,1520 | 1.1224519125778383,-0.20728341801373437,2.0501568052051606,0.2910734677256283,-1.0839642060391366,0.04309508514240472,4.9168542761704375,0.352714297145243,-0.35452613486786577,0.10530734984835549,-0.22826282947820883,0.14670037120281113,-0.5027007309924332,-0.5027007309924332,0.18802891238331532,0.14670037120281113,-0.12354522852272666,-0.9533513246189271,-0.8020539598800626,5.735788324107087,0.001537164702395684,-0.08178207009671594,-1.01854725430779,-0.2702763842063141,1.0423270044122548,-0.2702763842063141,-0.8667569312531026,1.9525878342172756,0.001537164702395684,-0.04008825025596049,0.06384901323418327,-0.22826282947820883,4.34572728753516,0.1673726504047501,-0.14445310808685582,-0.31236379292464844,0.5164299238420278,-1.0839642060391366,0.6995066854647584,0.14670037120281113,0.49601692885848886,-0.2492604414061187,-0.5665017880289501,-0.06092655176681376 | 2,945 |
Atpase binding | 9 | 29 | 2.526144 | 0.011532 | Q9BUN8,Q8NFQ8,P05026,Q9Y487,O76024,Q8IXB1,Q16740,Q93050,P11233 | Functions | GO Molecular function | msigdb_gomf | 38,74,201,140,76,206,15,187,313 | 76,201,313,1094,1953,1096,618,1252,1714,1396,1256,2728,15,520,206,352,74,1222,2029,187,38,1417,2904,1613,816,851,2364,1657,140 | 2.0891147678360613,1.1024392652871489,0.8007319209650764,0.12601197226717611,-0.2702763842063141,0.12601197226717611,0.4346904255440359,0.04309508514240472,-0.16537868346442086,-0.01926704960112091,0.04309508514240472,-1.01854725430779,4.53062075988975,0.5368284738518867,1.0824142734467934,0.7400374285311478,2.1280334391736364,0.06384901323418327,-0.29131079005371857,1.142452277500605,3.1270939109566753,-0.01926704960112091,-2.141652463609769,-0.10265492269446272,0.2910734677256283,0.27049579609526114,-0.5027007309924332,-0.12354522852272666,1.3616628687817531 | 2,945 |
Cis trans isomerase activity | 6 | 24 | 2.522847 | 0.011641 | Q9Y680,Q96AY3,Q13451,P62942,Q02790,Q9NWM8 | Functions | GO Molecular function | msigdb_gomf | 98,19,83,25,58,59 | 1991,1992,2572,2592,1131,2295,1857,2593,1590,25,801,58,2699,83,1147,1866,219,521,19,783,59,1281,613,98 | -0.29131079005371857,-0.29131079005371857,-0.7160969742146781,-0.7375531840373677,0.10530734984835549,-0.4602671791946553,-0.22826282947820883,-0.7375531840373677,-0.10265492269446272,3.768324465880385,0.2910734677256283,2.438006058944413,-0.9316674210504035,1.9916454712619938,0.10530734984835549,-0.22826282947820883,1.0423270044122548,0.5368284738518867,4.34572728753516,0.3116357123478239,2.438006058944413,0.04309508514240472,0.4551472654983724,1.835170758534991 | 2,945 |
Cerebral visual impairment | 14 | 58 | 2.52239 | 0.011656 | P03886,P00403,P55011,Q96N66,Q01105,Q08J23,P37268,Q9H270,Q96CU9,Q9H2M9,Q969N2,Q9UBB6,Q4G0N4,Q9HD42 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 2,166,232,394,170,392,12,339,113,246,152,356,285,385 | 2398,1791,2735,528,1994,1049,166,2,1471,2456,1094,1054,2429,662,617,1393,12,2539,1139,490,2346,232,2104,944,170,1962,392,1065,1641,2563,1067,1316,285,428,1875,1182,989,917,152,1228,2469,2584,113,1835,1559,394,1774,648,339,246,1455,2587,385,628,1280,356,923,2049 | -0.5452144624387532,-0.20728341801373437,-1.0403280423845351,0.5164299238420278,-0.29131079005371857,0.14670037120281113,1.2223321368163933,7.077162194942315,-0.06092655176681376,-0.587809634186986,0.12601197226717611,0.14670037120281113,-0.5665017880289501,0.3937322929558605,0.4346904255440359,-0.01926704960112091,4.770037134790452,-0.6732495316326513,0.10530734984835549,0.5572126623575777,-0.5027007309924332,1.0021895959906988,-0.33343552863307785,0.20866925843125922,1.202380291141655,-0.2702763842063141,0.6792207642978566,0.14670037120281113,-0.12354522852272666,-0.6946624831235061,0.14670037120281113,0.022324505727692668,0.8613062272321225,0.6386074394794051,-0.22826282947820883,0.08458639893558295,0.18802891238331532,0.2292937886448734,1.2821160279306807,0.06384901323418327,-0.587809634186986,-0.7160969742146781,1.6386402615157454,-0.20728341801373437,-0.08178207009671594,0.6792207642978566,-0.18632207833549766,0.4142187974298949,0.7602824013383189,0.9620015287859891,-0.04008825025596049,-0.7160969742146781,0.6995066854647584,0.4346904255440359,0.04309508514240472,0.7400374285311478,0.2292937886448734,-0.29131079005371857 | 2,945 |
Insulin receptor signaling pathway | 12 | 25 | 2.518706 | 0.011779 | Q9HCD5,P31751,Q92922,P43490,Q9UQB8,Q15043,P22413,Q8WWQ0,Q9BZF1,P62993,Q9H1E3,P25054 | Processes and pathways | GO Biological process | msigdb_gobp | 269,262,568,43,47,151,487,672,118,491,354,533 | 1047,1123,2202,1129,1296,487,533,262,43,1591,1539,491,2459,151,1364,669,672,1500,568,118,354,269,1461,47,2159 | 0.14670037120281113,0.10530734984835549,-0.3967645192768137,0.10530734984835549,0.022324505727692668,0.5572126623575777,0.5164299238420278,0.9016232814114782,2.860424771989179,-0.10265492269446272,-0.08178207009671594,0.5572126623575777,-0.587809634186986,1.2821160279306807,0.001537164702395684,0.3937322929558605,0.3937322929558605,-0.06092655176681376,0.49601692885848886,1.5992054978277717,0.7400374285311478,0.9016232814114782,-0.04008825025596049,2.688128608527772,-0.35452613486786577 | 2,945 |
Response to peptide | 32 | 90 | 2.517349 | 0.011824 | Q9HCD5,Q16836,P31751,Q9UNS1,Q15043,Q8WWQ0,Q6ZWJ1,O95251,P16435,P25054,Q08170,O75116,P35613,Q92922,P43490,Q9UQB8,O60763,P20020,P16220,P61026,Q13247,Q9Y266,P08670,Q05397,Q7L576,Q9H1E3,P42224,P61981,P22413,Q9BZF1,O75150,P62993 | Processes and pathways | GO Biological process | msigdb_gobp | 269,138,262,547,151,672,669,155,402,533,163,400,161,568,43,47,551,314,437,323,717,731,205,217,604,354,238,620,487,118,484,491 | 1662,1194,1047,1123,1794,703,551,400,484,155,862,1668,1470,2229,1951,205,1342,1850,2202,2055,1129,437,402,2172,1296,314,487,533,2557,262,161,1134,1808,936,238,1859,43,2099,1715,2100,1138,1591,1539,2521,2377,1718,2721,323,620,1639,491,1721,2348,217,2459,163,2066,1549,2139,717,1262,1821,151,1027,1028,138,1364,669,604,806,672,1500,568,2030,1606,1370,963,887,118,354,269,1701,1461,1421,1040,1936,547,47,731,2159 | -0.14445310808685582,0.06384901323418327,0.14670037120281113,0.10530734984835549,-0.20728341801373437,0.352714297145243,0.49601692885848886,0.6589210414523182,0.5572126623575777,1.262199946694982,0.2499026019446144,-0.14445310808685582,-0.06092655176681376,-0.417912582552414,-0.2702763842063141,1.0824142734467934,0.001537164702395684,-0.22826282947820883,-0.3967645192768137,-0.31236379292464844,0.10530734984835549,0.6182798801100748,0.6589210414523182,-0.37563575123099097,0.022324505727692668,0.8007319209650764,0.5572126623575777,0.5164299238420278,-0.6946624831235061,0.9016232814114782,1.2422720024056197,0.10530734984835549,-0.20728341801373437,0.20866925843125922,0.9821019275934442,-0.22826282947820883,2.860424771989179,-0.33343552863307785,-0.16537868346442086,-0.33343552863307785,0.10530734984835549,-0.10265492269446272,-0.08178207009671594,-0.6518579433658428,-0.5239474963343811,-0.16537868346442086,-0.9967910215997426,0.7805138743060999,0.4346904255440359,-0.12354522852272666,0.5572126623575777,-0.16537868346442086,-0.5027007309924332,1.0423270044122548,-0.587809634186986,1.2422720024056197,-0.31236379292464844,-0.08178207009671594,-0.35452613486786577,0.352714297145243,0.04309508514240472,-0.20728341801373437,1.2821160279306807,0.1673726504047501,0.1673726504047501,1.3815204900608,0.001537164702395684,0.3937322929558605,0.4551472654983724,0.2910734677256283,0.3937322929558605,-0.06092655176681376,0.49601692885848886,-0.29131079005371857,-0.10265492269446272,0.001537164702395684,0.20866925843125922,0.2499026019446144,1.5992054978277717,0.7400374285311478,0.9016232814114782,-0.14445310808685582,-0.04008825025596049,-0.01926704960112091,0.1673726504047501,-0.2492604414061187,0.5164299238420278,2.688128608527772,0.352714297145243,-0.35452613486786577 | 2,945 |
Abnormality of the thyroid gland | 20 | 98 | 2.514148 | 0.011932 | Q969G3,P03886,Q9UMX1,P61978,P42892,P48735,Q04656,Q9Y285,P00403,Q07021,Q15477,O60313,O76024,Q96T58,P21281,P42224,Q13423,P21912,Q06787,Q15056 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 257,2,260,134,264,145,148,289,166,178,302,174,76,208,105,238,112,119,254,255 | 1991,678,820,1047,1706,970,2535,702,174,2087,1996,595,76,2453,899,1011,1905,166,2825,790,2,1997,1668,530,2456,2671,105,119,1391,487,533,1630,1803,2001,641,1019,1134,238,937,264,902,145,1716,1482,905,1756,769,1022,2377,2062,134,1143,148,254,178,1443,986,112,1600,873,1361,1067,2068,255,302,2676,2653,2069,2643,2249,2110,691,1182,2611,539,672,2512,1879,2188,257,693,208,2076,1841,1695,1378,1703,1617,787,260,1424,342,548,2047,289,1241,2647,482 | -0.29131079005371857,0.37323082292864296,0.27049579609526114,0.14670037120281113,-0.16537868346442086,0.18802891238331532,-0.6732495316326513,0.352714297145243,1.1824164060489466,-0.33343552863307785,-0.29131079005371857,0.4551472654983724,2.0891147678360613,-0.587809634186986,0.2292937886448734,0.1673726504047501,-0.2492604414061187,1.2223321368163933,-1.3701528148541127,0.2910734677256283,7.077162194942315,-0.29131079005371857,-0.14445310808685582,0.5164299238420278,-0.587809634186986,-0.8883704331508439,1.7370381436593936,1.5794717175274886,-0.01926704960112091,0.5572126623575777,0.5164299238420278,-0.12354522852272666,-0.20728341801373437,-0.29131079005371857,0.4142187974298949,0.1673726504047501,0.10530734984835549,0.9821019275934442,0.20866925843125922,0.9016232814114782,0.2292937886448734,1.321912831571934,-0.16537868346442086,-0.06092655176681376,0.2292937886448734,-0.18632207833549766,0.3116357123478239,0.1673726504047501,-0.5239474963343811,-0.31236379292464844,1.4212012137589964,0.10530734984835549,1.3020203038267055,0.921762273203752,1.1824164060489466,-0.04008825025596049,0.18802891238331532,1.6583413438014383,-0.10265492269446272,0.2499026019446144,0.001537164702395684,0.14670037120281113,-0.31236379292464844,0.921762273203752,0.8209366140972024,-0.8883704331508439,-0.845166484742484,-0.31236379292464844,-0.8235988933073602,-0.417912582552414,-0.33343552863307785,0.37323082292864296,0.08458639893558295,-0.7590312945413134,0.5164299238420278,0.3937322929558605,-0.6304875446399937,-0.22826282947820883,-0.37563575123099097,0.921762273203752,0.37323082292864296,1.0824142734467934,-0.31236379292464844,-0.20728341801373437,-0.14445310808685582,0.001537164702395684,-0.14445310808685582,-0.10265492269446272,0.3116357123478239,0.921762273203752,-0.01926704960112091,0.7602824013383189,0.5164299238420278,-0.29131079005371857,0.8613062272321225,0.06384901323418327,-0.8235988933073602,0.5775825719273033 | 2,945 |
Organelle subcompartment | 55 | 352 | 2.498736 | 0.012464 | P07099,Q15392,O60725,Q9UGP8,Q99720,Q4J6C6,P37268,Q9UBF8,P35670,Q5H8A4,Q04656,Q9NZ08,Q969N2,P62942,Q92538,Q6NUQ1,Q14739,Q8N511,Q9H3N1,P35613,Q9BUN8,Q9Y282,Q5JRA6,Q86XL3,O43852,P04439,Q9BQE5,Q92643,P04843,P24390,P43307,Q96G23,O00264,Q8NHP6,Q8NFQ8,O76024,O75844,Q86UE4,Q6UWP7,P48449,P30519,Q16850,P49257,Q07065,P35610,Q9HD20,Q8N0U8,Q8TCJ2,O15027,O15260,Q9BS26,Q9H2M9,Q9BZF1,Q969E2,Q12907 | Localization | GO Cellular component | msigdb_gocc | 4,5,6,270,8,137,12,16,272,275,148,22,152,25,288,28,29,30,159,161,38,41,172,46,48,175,51,52,184,64,68,72,192,73,74,76,80,81,211,91,96,101,231,233,107,253,110,111,236,114,245,246,118,122,123 | 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| 2,945 |
Positive regulation of rna splicing | 8 | 23 | 2.497989 | 0.01249 | Q96QD8,P62995,P52948,Q96E39,P38159,Q8WVV9,P98179,Q14011 | Processes and pathways | GO Biological process | msigdb_gobp | 66,197,295,173,109,242,61,93 | 1901,1092,1294,532,2344,2092,2373,109,295,197,61,872,2139,946,346,93,242,173,1834,66,1331,1238,733 | -0.2492604414061187,0.12601197226717611,0.022324505727692668,0.5164299238420278,-0.5027007309924332,-0.33343552863307785,-0.5239474963343811,1.6780316249499048,0.8411280257469278,1.1224519125778383,2.399390495804993,0.2499026019446144,-0.35452613486786577,0.20866925843125922,0.7400374285311478,1.8939254041622147,0.9620015287859891,1.202380291141655,-0.20728341801373437,2.3607380919625607,0.022324505727692668,0.06384901323418327,0.352714297145243 | 2,945 |
Transition metal ion binding | 41 | 172 | 2.494637 | 0.012609 | Q5JRX3,Q8NCC3,Q32P28,P42892,Q03164,P35670,Q04656,Q8NB78,Q9NZ08,O60888,Q16629,O95251,Q02809,Q07864,P00403,Q8N4Q0,P55786,P22830,P13674,Q6UW02,P43243,Q99536,P19474,Q86YP4,Q9NWT6,Q5VUA4,Q8N8N7,Q8N4A0,Q5JTZ9,Q99707,Q9UPP1,O15460,Q16850,Q9NUD5,Q9BWF3,Q15637,Q9UIQ6,P22413,Q9NVH0,Q9HD42,Q05682 | Functions | GO Molecular function | msigdb_gomf | 266,7,136,264,13,272,148,21,22,23,407,155,404,162,166,44,45,420,176,442,424,189,186,459,204,456,75,82,350,477,223,100,101,234,239,363,116,487,386,385,492 | 1845,819,821,100,1946,2890,23,1901,2427,825,1903,2660,1386,1578,1579,155,1580,2786,2661,2536,166,2825,2690,2537,1668,2229,1342,1624,1850,2576,2714,176,1129,1296,186,487,420,1199,2484,2432,1856,707,2691,865,555,708,976,1803,272,1673,2002,1956,264,424,1135,559,2503,2749,765,1254,1589,1540,1481,766,2102,1355,2605,769,45,834,2506,1681,1819,404,13,148,2636,492,162,714,908,2065,562,1360,493,1103,1104,1764,1211,1068,1148,363,1362,2847,407,1028,101,136,2070,2024,266,350,2665,803,456,2109,912,2788,442,2072,2112,1730,459,1368,82,44,2611,75,21,7,2308,1185,884,1832,1269,1606,674,1326,1836,2388,1924,2682,189,1884,607,477,2778,1982,2547,2548,1276,239,2861,650,1563,1455,1738,385,2686,1654,234,386,2081,204,2495,22,2629,2394,1617,116,2824,1781,1464,1782,223,1044,1083,2339,1284,926,2497,1520 | -0.22826282947820883,0.27049579609526114,0.27049579609526114,1.7763226939226555,-0.2702763842063141,-1.9572118375424268,3.8057770547646164,-0.2492604414061187,-0.5665017880289501,0.27049579609526114,-0.2492604414061187,-0.8667569312531026,-0.01926704960112091,-0.10265492269446272,-0.10265492269446272,1.262199946694982,-0.10265492269446272,-1.1935008981215134,-0.8667569312531026,-0.6732495316326513,1.2223321368163933,-1.3701528148541127,-0.9100071940702691,-0.6732495316326513,-0.14445310808685582,-0.417912582552414,0.001537164702395684,-0.12354522852272666,-0.22826282947820883,-0.7160969742146781,-0.9750591188791282,1.1824164060489466,0.10530734984835549,0.022324505727692668,1.142452277500605,0.5572126623575777,0.6386074394794051,0.06384901323418327,-0.609138164405286,-0.5665017880289501,-0.22826282947820883,0.352714297145243,-0.9100071940702691,0.2499026019446144,0.49601692885848886,0.352714297145243,0.18802891238331532,-0.20728341801373437,0.8814712891547717,-0.14445310808685582,-0.29131079005371857,-0.2702763842063141,0.9016232814114782,0.6386074394794051,0.10530734984835549,0.49601692885848886,-0.6304875446399937,-1.0839642060391366,0.3116357123478239,0.04309508514240472,-0.10265492269446272,-0.08178207009671594,-0.06092655176681376,0.3116357123478239,-0.33343552863307785,0.001537164702395684,-0.7590312945413134,0.3116357123478239,2.841314827134973,0.27049579609526114,-0.6304875446399937,-0.14445310808685582,-0.20728341801373437,0.6589210414523182,4.659667932546476,1.3020203038267055,-0.8020539598800626,0.5572126623575777,1.2422720024056197,0.352714297145243,0.2292937886448734,-0.31236379292464844,0.49601692885848886,0.001537164702395684,0.5572126623575777,0.12601197226717611,0.12601197226717611,-0.18632207833549766,0.06384901323418327,0.14670037120281113,0.10530734984835549,0.7197788815940095,0.001537164702395684,-1.5262302338877283,0.6589210414523182,0.1673726504047501,1.7763226939226555,1.4013665868313239,-0.31236379292464844,-0.29131079005371857,0.9016232814114782,0.7400374285311478,-0.8667569312531026,0.2910734677256283,0.597938284242163,-0.33343552863307785,0.2292937886448734,-1.1935008981215134,0.6182798801100748,-0.31236379292464844,-0.33343552863307785,-0.16537868346442086,0.597938284242163,0.001537164702395684,2.011159223322583,2.860424771989179,-0.7590312945413134,2.1085789946182025,4.01126221185754,5.6091396582180515,-0.4602671791946553,0.08458639893558295,0.2499026019446144,-0.20728341801373437,0.04309508514240472,-0.10265492269446272,0.3937322929558605,0.022324505727692668,-0.20728341801373437,-0.5239474963343811,-0.2492604414061187,-0.8883704331508439,1.142452277500605,-0.22826282947820883,0.4551472654983724,0.5775825719273033,-1.1496084842326584,-0.2702763842063141,-0.6732495316326513,-0.6732495316326513,0.04309508514240472,0.9821019275934442,-1.6386272017792467,0.4142187974298949,-0.08178207009671594,-0.04008825025596049,-0.16537868346442086,0.6995066854647584,-0.8883704331508439,-0.12354522852272666,1.0021895959906988,0.6995066854647584,-0.31236379292464844,1.1024392652871489,-0.609138164405286,3.824492664661767,-0.7805314905603624,-0.5239474963343811,-0.10265492269446272,1.618928329270631,-1.3479736939343891,-0.18632207833549766,-0.04008825025596049,-0.18632207833549766,1.0423270044122548,0.1673726504047501,0.14670037120281113,-0.4814740099977851,0.04309508514240472,0.2292937886448734,-0.609138164405286,-0.06092655176681376 | 2,945 |
Abnormal glucose homeostasis | 26 | 166 | 2.493449 | 0.012651 | P03886,Q9UMX1,Q4J6C6,Q16836,P11310,P00846,Q04656,O43772,P00403,Q5JRA6,O60313,O96000,O00330,Q9H845,O76024,O75844,P61457,Q8TAA9,Q92620,P35610,P42224,Q13423,Q96CU9,Q13217,Q06787,Q15056 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 2,260,137,138,11,18,148,34,166,172,174,63,193,70,76,80,86,221,229,107,238,112,113,241,254,255 | 1193,2288,1991,193,678,1706,576,2648,2918,702,1945,34,1468,174,1995,1577,373,2089,705,1050,2688,1996,80,1163,1903,76,1950,1387,973,1527,899,63,2053,166,18,790,2,1668,2830,1243,1013,763,826,1624,530,864,11,2832,2456,2234,1671,1168,2727,684,1296,2204,487,828,1477,2519,2093,1200,2129,262,1803,2001,641,1133,107,1673,1806,1353,1752,1134,1808,1908,238,1859,1056,937,557,2404,1099,560,1137,2376,2580,2869,1482,2008,869,1140,1814,1960,1022,2010,86,1864,1143,472,2321,452,148,254,1443,241,112,948,255,2108,666,1028,138,538,137,172,2782,1873,1828,1875,2546,2794,2936,2509,1183,2511,221,672,432,2564,229,1321,1322,113,1504,1836,2860,2074,1841,70,2765,1512,2115,2755,1419,850,1459,1779,1082,1118,1617,787,260,1424,654,1042,1516,732,2083,1517,1192,1241,2647,2863,2160,299 | 0.06384901323418327,-0.4602671791946553,-0.29131079005371857,1.1224519125778383,0.37323082292864296,-0.16537868346442086,0.4755894045159319,-0.845166484742484,-2.894826421250636,0.352714297145243,-0.2702763842063141,3.392192755458683,-0.06092655176681376,1.1824164060489466,-0.29131079005371857,-0.10265492269446272,0.6995066854647584,-0.33343552863307785,0.352714297145243,0.14670037120281113,-0.9100071940702691,-0.29131079005371857,2.0501568052051606,0.08458639893558295,-0.2492604414061187,2.0891147678360613,-0.2702763842063141,-0.01926704960112091,0.18802891238331532,-0.08178207009671594,0.2292937886448734,2.3800689170256426,-0.31236379292464844,1.2223321368163933,4.364245678303629,0.2910734677256283,7.077162194942315,-0.14445310808685582,-1.3923607141779688,0.04309508514240472,0.1673726504047501,0.3116357123478239,0.27049579609526114,-0.12354522852272666,0.5164299238420278,0.2499026019446144,4.9168542761704375,-1.3923607141779688,-0.587809634186986,-0.417912582552414,-0.14445310808685582,0.08458639893558295,-1.01854725430779,0.37323082292864296,0.022324505727692668,-0.3967645192768137,0.5572126623575777,0.27049579609526114,-0.06092655176681376,-0.6518579433658428,-0.33343552863307785,0.06384901323418327,-0.35452613486786577,0.9016232814114782,-0.20728341801373437,-0.29131079005371857,0.4142187974298949,0.10530734984835549,1.7173799770740772,-0.14445310808685582,-0.20728341801373437,0.001537164702395684,-0.18632207833549766,0.10530734984835549,-0.20728341801373437,-0.2492604414061187,0.9821019275934442,-0.22826282947820883,0.14670037120281113,0.20866925843125922,0.49601692885848886,-0.5452144624387532,0.12601197226717611,0.49601692885848886,0.10530734984835549,-0.5239474963343811,-0.7160969742146781,-1.7064250666788545,-0.06092655176681376,-0.29131079005371857,0.2499026019446144,0.10530734984835549,-0.20728341801373437,-0.2702763842063141,0.1673726504047501,-0.29131079005371857,1.9525878342172756,-0.22826282947820883,0.10530734984835549,0.5775825719273033,-0.4814740099977851,0.597938284242163,1.3020203038267055,0.921762273203752,-0.04008825025596049,0.9620015287859891,1.6583413438014383,0.20866925843125922,0.921762273203752,-0.33343552863307785,0.3937322929558605,0.1673726504047501,1.3815204900608,0.5164299238420278,1.4013665868313239,1.202380291141655,-1.1715415663081576,-0.22826282947820883,-0.20728341801373437,-0.22826282947820883,-0.6732495316326513,-1.2154867397644784,-4.537593048427522,-0.6304875446399937,0.08458639893558295,-0.6304875446399937,1.0423270044122548,0.3937322929558605,0.6386074394794051,-0.6946624831235061,1.0222645998514908,0.022324505727692668,0.022324505727692668,1.6386402615157454,-0.06092655176681376,-0.20728341801373437,-1.6386272017792467,-0.31236379292464844,-0.20728341801373437,2.2057541946060866,-1.105820052560868,-0.06092655176681376,-0.33343552863307785,-1.0839642060391366,-0.01926704960112091,0.27049579609526114,-0.04008825025596049,-0.18632207833549766,0.14670037120281113,0.12601197226717611,-0.10265492269446272,0.3116357123478239,0.921762273203752,-0.01926704960112091,0.4142187974298949,0.1673726504047501,-0.06092655176681376,0.352714297145243,-0.31236379292464844,-0.06092655176681376,0.08458639893558295,0.06384901323418327,-0.8235988933073602,-1.6386272017792467,-0.35452613486786577,0.8411280257469278 | 2,945 |
dehydrogenase | 9 | 63 | 2.489532 | 0.012791 | P03886,P05091,Q9H845,P11310,Q13423,O94788,Q96CU9,P21912,P30837 | Functions | Panther Protein class | panther_protein_class | 2,67,70,11,112,49,113,119,55 | 1791,1468,321,1577,705,595,49,2574,2053,2,2228,67,2342,1849,932,11,1852,2576,1473,1168,2204,119,2431,2093,55,1750,2208,2005,2486,557,2404,145,2635,1099,1137,2580,868,1592,1909,1355,1910,1819,2439,907,112,2780,1496,1554,1031,2330,2466,1322,113,1152,750,433,70,2570,1280,2940,2197,1933,2854 | -0.20728341801373437,-0.06092655176681376,0.7805138743060999,-0.10265492269446272,0.352714297145243,0.4551472654983724,2.6113277676568396,-0.7160969742146781,-0.31236379292464844,7.077162194942315,-0.417912582552414,2.341397984173776,-0.5027007309924332,-0.22826282947820883,0.20866925843125922,4.9168542761704375,-0.22826282947820883,-0.7160969742146781,-0.06092655176681376,0.08458639893558295,-0.3967645192768137,1.5794717175274886,-0.5665017880289501,-0.33343552863307785,2.4573001148610345,-0.18632207833549766,-0.3967645192768137,-0.29131079005371857,-0.609138164405286,0.49601692885848886,-0.5452144624387532,1.321912831571934,-0.8020539598800626,0.12601197226717611,0.10530734984835549,-0.7160969742146781,0.2499026019446144,-0.10265492269446272,-0.2492604414061187,0.001537164702395684,-0.2492604414061187,-0.20728341801373437,-0.5665017880289501,0.2292937886448734,1.6583413438014383,-1.1715415663081576,-0.06092655176681376,-0.08178207009671594,0.1673726504047501,-0.4814740099977851,-0.587809634186986,0.022324505727692668,1.6386402615157454,0.10530734984835549,0.33218262437609547,0.6386074394794051,2.2057541946060866,-0.6946624831235061,0.04309508514240472,-5.9391553365988985,-0.37563575123099097,-0.2492604414061187,-1.5710975994835399 | 2,945 |
Rna splicing via transesterification reactions | 61 | 156 | 2.478353 | 0.013199 | P31943,O75934,Q99459,P61978,Q9Y4C8,O60306,P98175,Q07666,Q16629,P52272,P52756,P07910,P19338,Q08170,P11940,Q8WWY3,Q96I25,P52948,O43390,Q96E39,Q07021,Q12874,O60828,P51991,Q14562,Q96PK6,P51114,P51116,P98179,Q9Y5S9,Q96PU8,P31942,Q9Y2W2,P62995,Q9UJV9,Q07955,Q13247,O43290,Q13242,O43172,P23246,Q13123,Q9Y3C6,O60506,Q14011,Q92620,Q13595,P52597,P22626,Q9Y3B4,Q96MU7,Q96DF8,Q9BWF3,P38159,P09651,Q15637,Q13435,P41223,Q15459,Q06787,O75494 | Processes and pathways | GO Biological process | msigdb_gobp | 375,374,523,134,527,636,515,273,407,535,663,401,532,163,660,432,694,295,169,173,178,562,682,182,56,188,439,686,61,465,330,195,464,197,462,324,717,447,77,576,333,453,613,215,93,229,346,225,224,634,368,367,239,109,359,363,494,488,518,254,127 | 1380,1786,1084,1787,576,447,169,2648,1992,1005,1382,2400,636,2650,215,682,1006,823,127,1125,1050,374,1051,1387,401,930,1092,863,359,1167,1294,660,1670,2171,933,1054,532,224,333,2092,1392,2373,935,195,375,109,1585,2003,488,1020,1480,439,686,182,535,225,663,295,1438,1256,2241,134,1680,1142,2793,1440,2663,197,2878,871,515,61,1722,2642,254,178,273,324,163,1492,872,1100,562,453,77,2139,717,494,2410,946,346,1263,93,1601,56,1725,1765,1766,518,363,407,1176,910,2275,2070,1729,912,1873,1215,2072,1267,2693,1185,1831,432,1225,229,918,1226,783,2584,367,2566,173,1834,694,368,188,330,2389,523,1608,239,2334,1154,1986,2192,1700,1331,1332,2933,462,1236,1238,1937,733,464,1240,2697,1619,634,613,2200,527,2812,465 | -0.01926704960112091,-0.20728341801373437,0.12601197226717611,-0.20728341801373437,0.4755894045159319,0.597938284242163,1.202380291141655,-0.845166484742484,-0.29131079005371857,0.1673726504047501,-0.01926704960112091,-0.5452144624387532,0.4142187974298949,-0.845166484742484,1.0423270044122548,0.37323082292864296,0.1673726504047501,0.27049579609526114,1.4806368149043725,0.10530734984835549,0.14670037120281113,0.6995066854647584,0.14670037120281113,-0.01926704960112091,0.6589210414523182,0.20866925843125922,0.12601197226717611,0.2499026019446144,0.7197788815940095,0.08458639893558295,0.022324505727692668,0.3937322929558605,-0.14445310808685582,-0.37563575123099097,0.20866925843125922,0.14670037120281113,0.5164299238420278,1.0222645998514908,0.7602824013383189,-0.33343552863307785,-0.01926704960112091,-0.5239474963343811,0.20866925843125922,1.1224519125778383,0.6995066854647584,1.6780316249499048,-0.10265492269446272,-0.29131079005371857,0.5572126623575777,0.1673726504047501,-0.06092655176681376,0.6182798801100748,0.37323082292864296,1.1624404216515005,0.5164299238420278,1.0222645998514908,0.3937322929558605,0.8411280257469278,-0.04008825025596049,0.04309508514240472,-0.417912582552414,1.4212012137589964,-0.14445310808685582,0.10530734984835549,-1.2154867397644784,-0.04008825025596049,-0.8667569312531026,1.1224519125778383,-1.7972284475701508,0.2499026019446144,0.5368284738518867,2.399390495804993,-0.16537868346442086,-0.8235988933073602,0.921762273203752,1.1824164060489466,0.8814712891547717,0.7805138743060999,1.2422720024056197,-0.06092655176681376,0.2499026019446144,0.12601197226717611,0.49601692885848886,0.597938284242163,2.0891147678360613,-0.35452613486786577,0.352714297145243,0.5572126623575777,-0.5452144624387532,0.20866925843125922,0.7400374285311478,0.04309508514240472,1.8939254041622147,-0.10265492269446272,2.4573001148610345,-0.16537868346442086,-0.18632207833549766,-0.18632207833549766,0.5368284738518867,0.7197788815940095,0.6589210414523182,0.08458639893558295,0.2292937886448734,-0.4390800866390325,-0.31236379292464844,-0.16537868346442086,0.2292937886448734,-0.22826282947820883,0.06384901323418327,-0.31236379292464844,0.04309508514240472,-0.9100071940702691,0.08458639893558295,-0.20728341801373437,0.6386074394794051,0.06384901323418327,1.0222645998514908,0.2292937886448734,0.06384901323418327,0.3116357123478239,-0.7160969742146781,0.7197788815940095,-0.6946624831235061,1.202380291141655,-0.20728341801373437,0.37323082292864296,0.7197788815940095,1.142452277500605,0.7805138743060999,-0.5239474963343811,0.5368284738518867,-0.10265492269446272,0.9821019275934442,-0.4814740099977851,0.10530734984835549,-0.2702763842063141,-0.37563575123099097,-0.14445310808685582,0.022324505727692668,0.022324505727692668,-4.163068613869287,0.597938284242163,0.06384901323418327,0.06384901323418327,-0.2492604414061187,0.352714297145243,0.597938284242163,0.06384901323418327,-0.9100071940702691,-0.10265492269446272,0.4346904255440359,0.4551472654983724,-0.37563575123099097,0.5368284738518867,-1.2595390174555432,0.597938284242163 | 2,945 |
Fibrous tissue neoplasm | 9 | 18 | 2.470308 | 0.0135 | Q969G3,Q13126,Q9UMX1,Q15392,P21281,P21912,Q01082,P16220,P25054 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 257,35,260,5,105,119,440,437,533 | 530,437,105,2372,827,119,533,2001,902,1716,1756,440,35,5,2110,257,1504,260 | 0.5164299238420278,0.6182798801100748,1.7370381436593936,-0.5239474963343811,0.27049579609526114,1.5794717175274886,0.5164299238420278,-0.29131079005371857,0.2292937886448734,-0.16537868346442086,-0.18632207833549766,0.6182798801100748,3.373307610643455,5.735788324107087,-0.33343552863307785,0.921762273203752,-0.06092655176681376,0.921762273203752 | 2,945 |
Abnormal oral physiology | 16 | 53 | 2.468798 | 0.013557 | Q15165,O15460,Q15233,P55011,P09651,P55795,Q92804,P35670,Q03252,Q96T58,P43243,P35637,Q6UN15,Q8N0X7,Q01082,Q14739 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 0,100,517,232,359,514,180,272,452,208,424,115,125,251,440,29 | 1706,100,2313,2855,1164,739,763,1245,2482,1472,2556,359,931,530,1851,1531,1907,976,115,272,1134,1860,424,1481,711,982,2132,799,232,1679,514,2651,440,906,452,2607,2018,1146,718,948,29,1314,0,517,125,251,180,2188,2513,208,1187,1455,700 | -0.16537868346442086,1.7763226939226555,-0.4814740099977851,-1.5935772487808675,0.08458639893558295,0.33218262437609547,0.3116357123478239,0.04309508514240472,-0.609138164405286,-0.06092655176681376,-0.6946624831235061,0.7197788815940095,0.20866925843125922,0.5164299238420278,-0.22826282947820883,-0.08178207009671594,-0.2492604414061187,0.18802891238331532,1.618928329270631,0.8814712891547717,0.10530734984835549,-0.22826282947820883,0.6386074394794051,-0.06092655176681376,0.352714297145243,0.18802891238331532,-0.35452613486786577,0.2910734677256283,1.0021895959906988,-0.14445310808685582,0.5368284738518867,-0.845166484742484,0.6182798801100748,0.2292937886448734,0.597938284242163,-0.7590312945413134,-0.29131079005371857,0.10530734984835549,0.352714297145243,0.20866925843125922,3.655794126757704,0.022324505727692668,7.623940234694683,0.5368284738518867,1.5004260995112062,0.9418883330481125,1.1824164060489466,-0.37563575123099097,-0.6304875446399937,1.0824142734467934,0.08458639893558295,-0.04008825025596049,0.37323082292864296 | 2,945 |
Hyperammonemia | 6 | 35 | 2.458662 | 0.013946 | O43772,Q9H845,P35610,P11310,Q9Y619,Q6NUQ1 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 34,70,107,11,50,28 | 1193,34,2053,2454,2830,1243,1951,826,932,11,1346,828,1477,2519,1856,107,1673,1808,1677,1137,2869,982,1960,492,138,28,1152,2860,2074,2745,70,2765,1933,1935,50 | 0.06384901323418327,3.392192755458683,-0.31236379292464844,-0.587809634186986,-1.3923607141779688,0.04309508514240472,-0.2702763842063141,0.27049579609526114,0.20866925843125922,4.9168542761704375,0.001537164702395684,0.27049579609526114,-0.06092655176681376,-0.6518579433658428,-0.22826282947820883,1.7173799770740772,-0.14445310808685582,-0.20728341801373437,-0.14445310808685582,0.10530734984835549,-1.7064250666788545,0.18802891238331532,-0.2702763842063141,0.5572126623575777,1.3815204900608,3.6745672923672013,0.10530734984835549,-1.6386272017792467,-0.31236379292464844,-1.0621336151647116,2.2057541946060866,-1.105820052560868,-0.2492604414061187,-0.2492604414061187,2.592105567404909 | 2,945 |
Regulation of mrna splicing via spliceosome | 22 | 56 | 2.449317 | 0.014313 | P61978,Q07666,Q16629,Q08170,P52948,Q96E39,Q07021,P51114,P98179,Q96PU8,P62995,Q13242,Q14011,Q13595,P22626,Q96MU7,Q9BWF3,P38159,P09651,Q15637,Q06787,O75494 | Processes and pathways | GO Biological process | msigdb_gobp | 134,273,407,163,295,173,178,439,61,330,197,77,93,346,224,368,239,109,359,363,254,127 | 1786,127,1092,359,1294,1670,933,1054,532,224,2092,1392,2373,935,109,1480,439,686,663,295,134,197,2878,871,515,61,1722,254,178,273,163,872,1100,77,717,946,346,93,1601,363,407,910,2275,2693,918,173,1834,368,330,2389,239,1154,2933,1238,733,465 | -0.20728341801373437,1.4806368149043725,0.12601197226717611,0.7197788815940095,0.022324505727692668,-0.14445310808685582,0.20866925843125922,0.14670037120281113,0.5164299238420278,1.0222645998514908,-0.33343552863307785,-0.01926704960112091,-0.5239474963343811,0.20866925843125922,1.6780316249499048,-0.06092655176681376,0.6182798801100748,0.37323082292864296,0.3937322929558605,0.8411280257469278,1.4212012137589964,1.1224519125778383,-1.7972284475701508,0.2499026019446144,0.5368284738518867,2.399390495804993,-0.16537868346442086,0.921762273203752,1.1824164060489466,0.8814712891547717,1.2422720024056197,0.2499026019446144,0.12601197226717611,2.0891147678360613,0.352714297145243,0.20866925843125922,0.7400374285311478,1.8939254041622147,-0.10265492269446272,0.7197788815940095,0.6589210414523182,0.2292937886448734,-0.4390800866390325,-0.9100071940702691,0.2292937886448734,1.202380291141655,-0.20728341801373437,0.7197788815940095,0.7805138743060999,-0.5239474963343811,0.9821019275934442,0.10530734984835549,-4.163068613869287,0.06384901323418327,0.352714297145243,0.597938284242163 | 2,945 |
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