term
stringlengths
2
121
overlap
int64
6
281
setsize
int64
7
499
score
float64
1.96
10.6
pval
float64
0
0.05
edge
stringlengths
41
1.97k
type
stringclasses
5 values
subtype
stringclasses
24 values
subtype_key
stringclasses
24 values
edge_idxs
stringlengths
11
1.17k
ann_idxs
stringlengths
19
2.31k
ann_vals
stringlengths
124
9.94k
sig_size
int64
2.2k
3.73k
Defective cftr causes cystic fibrosis
11
41
2.444301
0.014513
P25787,P60900,P28072,Q9BUN8,Q99436,Q9GZP9,P20618,P51665,O00231,P49721,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
3,196,69,38,504,369,261,561,550,469,31
550,2398,2163,1523,1337,1622,1008,1672,261,1249,3,1533,2483,1631,31,69,829,2318,1809,2578,2505,469,561,1306,1679,196,580,1863,1638,1595,2244,1210,2750,1265,2279,504,1114,38,369,1237,1568
0.49601692885848886,-0.5452144624387532,-0.37563575123099097,-0.08178207009671594,0.001537164702395684,-0.12354522852272666,0.1673726504047501,-0.14445310808685582,0.9016232814114782,0.04309508514240472,6.86435802761024,-0.08178207009671594,-0.609138164405286,-0.12354522852272666,3.5053441140537633,2.2639439873853995,0.27049579609526114,-0.4814740099977851,-0.20728341801373437,-0.7160969742146781,-0.6304875446399937,0.5775825719273033,0.49601692885848886,0.022324505727692668,-0.14445310808685582,1.1224519125778383,0.4755894045159319,-0.22826282947820883,-0.12354522852272666,-0.10265492269446272,-0.417912582552414,0.06384901323418327,-1.0839642060391366,0.04309508514240472,-0.4390800866390325,0.5572126623575777,0.12601197226717611,3.1270939109566753,0.7197788815940095,0.06384901323418327,-0.08178207009671594
2,945
Abc transporter disorders
11
41
2.444301
0.014513
P25787,P60900,P28072,Q9BUN8,Q99436,Q9GZP9,P20618,P51665,O00231,P49721,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
3,196,69,38,504,369,261,561,550,469,31
550,2398,2163,1523,1337,1622,1008,1672,261,1249,3,1533,2483,1631,31,69,829,2318,1809,2578,2505,469,561,1306,1679,196,580,1863,1638,1595,2244,1210,2750,1265,2279,504,1114,38,369,1237,1568
0.49601692885848886,-0.5452144624387532,-0.37563575123099097,-0.08178207009671594,0.001537164702395684,-0.12354522852272666,0.1673726504047501,-0.14445310808685582,0.9016232814114782,0.04309508514240472,6.86435802761024,-0.08178207009671594,-0.609138164405286,-0.12354522852272666,3.5053441140537633,2.2639439873853995,0.27049579609526114,-0.4814740099977851,-0.20728341801373437,-0.7160969742146781,-0.6304875446399937,0.5775825719273033,0.49601692885848886,0.022324505727692668,-0.14445310808685582,1.1224519125778383,0.4755894045159319,-0.22826282947820883,-0.12354522852272666,-0.10265492269446272,-0.417912582552414,0.06384901323418327,-1.0839642060391366,0.04309508514240472,-0.4390800866390325,0.5572126623575777,0.12601197226717611,3.1270939109566753,0.7197788815940095,0.06384901323418327,-0.08178207009671594
2,945
Response to reactive oxygen species
6
33
2.44037
0.014672
Q96IZ0,P00374,Q99720,Q04656,P32119,O95831
Processes and pathways
GO Biological process
msigdb_gobp
128,1,8,148,210,89
89,1,862,2690,929,1292,2259,1295,1343,579,2177,2557,2094,1954,685,2295,210,2058,238,1675,2742,148,2607,945,1066,2467,128,2682,8,755,2038,1462,549
1.9330438639514882,7.448017023011698,0.2499026019446144,-0.9100071940702691,0.20866925843125922,0.022324505727692668,-0.4390800866390325,0.022324505727692668,0.001537164702395684,0.4755894045159319,-0.37563575123099097,-0.6946624831235061,-0.33343552863307785,-0.2702763842063141,0.37323082292864296,-0.4602671791946553,1.062376874281129,-0.31236379292464844,0.9821019275934442,-0.14445310808685582,-1.0621336151647116,1.3020203038267055,-0.7590312945413134,0.20866925843125922,0.14670037120281113,-0.587809634186986,1.4608362743298053,-0.8883704331508439,5.500372154885624,0.33218262437609547,-0.29131079005371857,-0.04008825025596049,0.5164299238420278
2,945
Regulation of mrna metabolic process
42
135
2.43677
0.014819
P67809,P61978,Q9NPI6,P98175,Q07666,Q16629,P52272,P07910,O75116,P19338,Q08170,Q6PD62,P52948,Q6PJT7,Q96E39,Q07021,Q92804,Q8N684,P51114,P98179,Q9Y5S9,Q96PU8,P62995,Q9P2K5,Q13242,P08670,Q99729,Q14103,O60506,Q14011,Q13595,P22626,Q96MU7,Q9BWF3,P38159,P09651,Q15637,P35637,Q9UIV1,O75150,Q06787,O75494
Processes and pathways
GO Biological process
msigdb_gobp
129,134,398,515,273,407,535,401,400,532,163,565,295,428,173,178,180,444,439,61,465,330,197,199,77,205,209,335,215,93,346,224,368,239,109,359,363,115,117,484,254,127
1193,2288,2161,968,1786,1793,1794,215,400,484,928,127,1384,1527,763,401,1092,205,863,359,1294,660,1670,933,1054,1345,532,1248,224,2092,1392,2557,2373,935,115,109,2003,980,1480,766,439,686,535,663,2102,295,134,2407,197,129,2878,871,515,61,1722,254,178,273,163,1492,872,1100,2018,563,77,717,1172,1262,946,346,1361,93,335,2245,1601,1444,1868,1726,363,988,1027,407,1212,910,2275,2678,644,2443,2110,1406,565,428,1030,1497,1407,2329,2693,444,916,1219,1976,806,1878,180,918,1269,1226,1978,1453,2584,173,1834,368,330,2389,209,239,2861,812,1154,695,627,398,2493,2285,755,1002,199,2933,117,1238,1570,1239,733,465
0.06384901323418327,-0.4602671791946553,-0.37563575123099097,0.18802891238331532,-0.20728341801373437,-0.20728341801373437,-0.20728341801373437,1.0423270044122548,0.6589210414523182,0.5572126623575777,0.20866925843125922,1.4806368149043725,-0.01926704960112091,-0.08178207009671594,0.3116357123478239,0.6589210414523182,0.12601197226717611,1.0824142734467934,0.2499026019446144,0.7197788815940095,0.022324505727692668,0.3937322929558605,-0.14445310808685582,0.20866925843125922,0.14670037120281113,0.001537164702395684,0.5164299238420278,0.04309508514240472,1.0222645998514908,-0.33343552863307785,-0.01926704960112091,-0.6946624831235061,-0.5239474963343811,0.20866925843125922,1.618928329270631,1.6780316249499048,-0.29131079005371857,0.18802891238331532,-0.06092655176681376,0.3116357123478239,0.6182798801100748,0.37323082292864296,0.5164299238420278,0.3937322929558605,-0.33343552863307785,0.8411280257469278,1.4212012137589964,-0.5452144624387532,1.1224519125778383,1.4410244250244986,-1.7972284475701508,0.2499026019446144,0.5368284738518867,2.399390495804993,-0.16537868346442086,0.921762273203752,1.1824164060489466,0.8814712891547717,1.2422720024056197,-0.06092655176681376,0.2499026019446144,0.12601197226717611,-0.29131079005371857,0.49601692885848886,2.0891147678360613,0.352714297145243,0.08458639893558295,0.04309508514240472,0.20866925843125922,0.7400374285311478,0.001537164702395684,1.8939254041622147,0.7602824013383189,-0.417912582552414,-0.10265492269446272,-0.04008825025596049,-0.22826282947820883,-0.16537868346442086,0.7197788815940095,0.18802891238331532,0.1673726504047501,0.6589210414523182,0.06384901323418327,0.2292937886448734,-0.4390800866390325,-0.8883704331508439,0.4142187974298949,-0.5665017880289501,-0.33343552863307785,-0.01926704960112091,0.49601692885848886,0.6386074394794051,0.1673726504047501,-0.06092655176681376,-0.01926704960112091,-0.4814740099977851,-0.9100071940702691,0.6182798801100748,0.2292937886448734,0.06384901323418327,-0.2702763842063141,0.2910734677256283,-0.22826282947820883,1.1824164060489466,0.2292937886448734,0.04309508514240472,0.06384901323418327,-0.2702763842063141,-0.04008825025596049,-0.7160969742146781,1.202380291141655,-0.20728341801373437,0.7197788815940095,0.7805138743060999,-0.5239474963343811,1.0824142734467934,0.9821019275934442,-1.6386272017792467,0.2910734677256283,0.10530734984835549,0.37323082292864296,0.4346904255440359,0.6792207642978566,-0.609138164405286,-0.4390800866390325,0.33218262437609547,0.18802891238331532,1.1224519125778383,-4.163068613869287,1.618928329270631,0.06384901323418327,-0.08178207009671594,0.06384901323418327,0.352714297145243,0.597938284242163
2,945
Transcriptional regulation by runx1
16
61
2.429986
0.015099
Q16625,Q969G3,P25787,Q13951,P60900,P28072,Q99436,Q92922,Q03164,P20618,Q8TAQ2,P51665,O00231,Q13547,P49721,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
348,257,3,283,196,69,504,568,13,261,539,561,550,54,469,31
550,2398,2163,820,1523,1337,1622,1796,1532,1672,2371,261,1249,3,1533,2483,1631,31,69,829,2318,1809,2578,2505,469,905,561,1306,196,580,2013,1863,1638,1595,1488,2104,13,2459,2244,1261,1210,54,283,2750,1265,2867,348,2249,878,539,2279,568,257,693,504,1114,1775,627,1003,1237,1568
0.49601692885848886,-0.5452144624387532,-0.37563575123099097,0.27049579609526114,-0.08178207009671594,0.001537164702395684,-0.12354522852272666,-0.20728341801373437,-0.08178207009671594,-0.14445310808685582,-0.5239474963343811,0.9016232814114782,0.04309508514240472,6.86435802761024,-0.08178207009671594,-0.609138164405286,-0.12354522852272666,3.5053441140537633,2.2639439873853995,0.27049579609526114,-0.4814740099977851,-0.20728341801373437,-0.7160969742146781,-0.6304875446399937,0.5775825719273033,0.2292937886448734,0.49601692885848886,0.022324505727692668,1.1224519125778383,0.4755894045159319,-0.29131079005371857,-0.22826282947820883,-0.12354522852272666,-0.10265492269446272,-0.06092655176681376,-0.33343552863307785,4.659667932546476,-0.587809634186986,-0.417912582552414,0.04309508514240472,0.06384901323418327,2.4765850676126675,0.8613062272321225,-1.0839642060391366,0.04309508514240472,-1.6837963753761036,0.7400374285311478,-0.417912582552414,0.2499026019446144,0.5164299238420278,-0.4390800866390325,0.49601692885848886,0.921762273203752,0.37323082292864296,0.5572126623575777,0.12601197226717611,-0.18632207833549766,0.4346904255440359,0.18802891238331532,0.06384901323418327,-0.08178207009671594
2,945
Uch proteinases
6
46
2.427921
0.015186
P25787,P60900,P28072,P20618,Q8NB78,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
3,196,69,261,21,31
550,2398,2163,1523,1123,1337,1622,1796,1672,261,1249,3,1533,2483,1631,31,69,829,2318,1809,2578,2505,469,2132,561,1306,196,580,1863,1638,1595,2652,2244,1210,2750,1265,1684,21,2279,504,1114,1237,1568,2364,290,2050
0.49601692885848886,-0.5452144624387532,-0.37563575123099097,-0.08178207009671594,0.10530734984835549,0.001537164702395684,-0.12354522852272666,-0.20728341801373437,-0.14445310808685582,0.9016232814114782,0.04309508514240472,6.86435802761024,-0.08178207009671594,-0.609138164405286,-0.12354522852272666,3.5053441140537633,2.2639439873853995,0.27049579609526114,-0.4814740099977851,-0.20728341801373437,-0.7160969742146781,-0.6304875446399937,0.5775825719273033,-0.35452613486786577,0.49601692885848886,0.022324505727692668,1.1224519125778383,0.4755894045159319,-0.22826282947820883,-0.12354522852272666,-0.10265492269446272,-0.845166484742484,-0.417912582552414,0.06384901323418327,-1.0839642060391366,0.04309508514240472,-0.14445310808685582,4.01126221185754,-0.4390800866390325,0.5572126623575777,0.12601197226717611,0.06384901323418327,-0.08178207009671594,-0.5027007309924332,0.8613062272321225,-0.29131079005371857
2,945
Protein hydroxylation
12
13
2.424421
0.015333
O15460,Q96HE7,Q32P28,Q13162,Q9NWT6,O75718,P07237,P13674,Q9H267,Q96AY3,Q02809,Q92791
Processes and pathways
GO Biological process
msigdb_gobp
100,586,136,583,204,388,418,176,545,19,404,92
100,388,418,176,404,642,583,136,92,19,586,545,204
1.7763226939226555,0.6792207642978566,0.6386074394794051,1.1824164060489466,0.6589210414523182,0.4142187974298949,0.4755894045159319,1.4013665868313239,1.9134897350999418,4.34572728753516,0.4755894045159319,0.5164299238420278,1.1024392652871489
2,945
Regulation of runx3 expression and activity
10
38
2.403136
0.016255
Q13951,P25787,P60900,P28072,Q99436,P20618,P51665,O00231,P49721,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
283,3,196,69,504,261,561,550,469,31
550,2398,2163,1523,1337,1622,1672,261,1249,3,1533,2483,1631,31,69,829,2318,937,1809,2578,2505,469,561,1306,196,580,1863,1638,1595,2244,1210,283,1265,2279,504,1114,1237,1568
0.49601692885848886,-0.5452144624387532,-0.37563575123099097,-0.08178207009671594,0.001537164702395684,-0.12354522852272666,-0.14445310808685582,0.9016232814114782,0.04309508514240472,6.86435802761024,-0.08178207009671594,-0.609138164405286,-0.12354522852272666,3.5053441140537633,2.2639439873853995,0.27049579609526114,-0.4814740099977851,0.20866925843125922,-0.20728341801373437,-0.7160969742146781,-0.6304875446399937,0.5775825719273033,0.49601692885848886,0.022324505727692668,1.1224519125778383,0.4755894045159319,-0.22826282947820883,-0.12354522852272666,-0.10265492269446272,-0.417912582552414,0.06384901323418327,0.8613062272321225,0.04309508514240472,-0.4390800866390325,0.5572126623575777,0.12601197226717611,0.06384901323418327,-0.08178207009671594
2,945
Abnormal circulating lipid concentration
16
72
2.399865
0.016401
O43772,Q15056,Q15392,Q9H845,P49257,P31751,P11310,P37268,Q16836,O75844,Q8N511,Q969N2,Q9Y285,Q14739,Q4G0N4,P28070
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
34,255,5,70,231,262,11,12,138,80,30,152,289,29,285,31
1706,680,702,34,2630,2089,80,825,1903,899,790,2767,1013,2932,826,11,1168,420,1477,31,1200,262,512,641,1133,1673,12,2939,1714,1808,2267,231,1137,315,2869,2008,1593,1814,1960,712,2826,1143,2722,452,908,986,2381,29,255,5,2653,2847,2582,138,285,30,625,1321,152,1836,2712,70,2532,2476,2599,2628,1617,1935,289,2647,482,1519
-0.16537868346442086,0.37323082292864296,0.352714297145243,3.392192755458683,-0.8020539598800626,-0.33343552863307785,2.0501568052051606,0.27049579609526114,-0.2492604414061187,0.2292937886448734,0.2910734677256283,-1.1277013965550577,0.1673726504047501,-3.890742390654541,0.27049579609526114,4.9168542761704375,0.08458639893558295,0.6386074394794051,-0.06092655176681376,3.5053441140537633,0.06384901323418327,0.9016232814114782,0.5368284738518867,0.4142187974298949,0.10530734984835549,-0.14445310808685582,4.770037134790452,-5.399061502057131,-0.16537868346442086,-0.20728341801373437,-0.4390800866390325,1.0021895959906988,0.10530734984835549,0.8007319209650764,-1.7064250666788545,-0.29131079005371857,-0.10265492269446272,-0.20728341801373437,-0.2702763842063141,0.352714297145243,-1.3701528148541127,0.10530734984835549,-0.9967910215997426,0.597938284242163,0.2292937886448734,0.18802891238331532,-0.5239474963343811,3.655794126757704,0.921762273203752,5.735788324107087,-0.845166484742484,-1.5262302338877283,-0.7160969742146781,1.3815204900608,0.8613062272321225,3.6182258797931914,0.4346904255440359,0.022324505727692668,1.2821160279306807,-0.20728341801373437,-0.9533513246189271,2.2057541946060866,-0.6518579433658428,-0.587809634186986,-0.7375531840373677,-0.7805314905603624,-0.10265492269446272,-0.2492604414061187,0.8613062272321225,-0.8235988933073602,0.5775825719273033,-0.06092655176681376
2,945
Regulation of response to external stimulus
24
115
2.395869
0.016581
Q9NZ08,Q9Y4E8,P28070,P80303,Q07021,P04439,P19174,Q96PK6,P19474,P60900,Q96G23,Q8NHP6,P49593,O75844,P23246,O75179,P32119,Q05397,Q9UMX5,P55011,Q9NUD5,P42224,Q9UIV1,P10586
Processes and pathways
GO Biological process
msigdb_gobp
22,290,31,40,178,175,53,188,186,196,72,73,202,80,333,331,210,217,103,232,234,238,117,249
678,854,701,2292,1899,682,511,761,331,2201,2427,80,552,1007,859,860,2825,739,2746,862,175,2906,900,2670,1197,1128,249,2886,343,1530,2913,1296,53,186,2372,333,1249,1097,2177,707,31,2094,2296,210,2130,238,424,202,1717,2009,2319,1959,232,1022,941,196,1257,1864,1721,40,621,1026,405,217,2459,178,1492,1493,516,1066,946,2562,1173,1444,2068,517,2140,1966,1918,666,1027,1919,2248,1727,913,1368,2414,460,990,73,1222,1976,1499,722,1879,1649,72,1692,188,784,2682,888,1187,2391,1456,234,1741,755,2614,22,1002,117,103,1936,290
0.37323082292864296,0.2499026019446144,0.352714297145243,-0.4602671791946553,-0.2492604414061187,0.37323082292864296,0.5368284738518867,0.3116357123478239,0.7602824013383189,-0.3967645192768137,-0.5665017880289501,2.0501568052051606,0.49601692885848886,0.1673726504047501,0.2499026019446144,0.2499026019446144,-1.3701528148541127,0.33218262437609547,-1.0839642060391366,0.2499026019446144,1.1824164060489466,-2.23448571265435,0.2292937886448734,-0.8883704331508439,0.06384901323418327,0.10530734984835549,0.9418883330481125,-1.9113655148381163,0.7400374285311478,-0.08178207009671594,-2.586040646525843,0.022324505727692668,2.4765850676126675,1.142452277500605,-0.5239474963343811,0.7602824013383189,0.04309508514240472,0.12601197226717611,-0.37563575123099097,0.352714297145243,3.5053441140537633,-0.33343552863307785,-0.4602671791946553,1.062376874281129,-0.35452613486786577,0.9821019275934442,0.6386074394794051,1.1024392652871489,-0.16537868346442086,-0.29131079005371857,-0.4814740099977851,-0.2702763842063141,1.0021895959906988,0.1673726504047501,0.20866925843125922,1.1224519125778383,0.04309508514240472,-0.22826282947820883,-0.16537868346442086,2.91770423556765,0.4346904255440359,0.1673726504047501,0.6589210414523182,1.0423270044122548,-0.587809634186986,1.1824164060489466,-0.06092655176681376,-0.06092655176681376,0.5368284738518867,0.14670037120281113,0.20866925843125922,-0.6946624831235061,0.08458639893558295,-0.04008825025596049,-0.31236379292464844,0.5368284738518867,-0.35452613486786577,-0.2702763842063141,-0.2492604414061187,0.3937322929558605,0.1673726504047501,-0.2492604414061187,-0.417912582552414,-0.16537868346442086,0.2292937886448734,0.001537164702395684,-0.5452144624387532,0.597938284242163,0.18802891238331532,2.147478141707137,0.06384901323418327,-0.2702763842063141,-0.06092655176681376,0.352714297145243,-0.22826282947820883,-0.12354522852272666,2.166913142114243,-0.14445310808685582,1.142452277500605,0.3116357123478239,-0.8883704331508439,0.2499026019446144,0.08458639893558295,-0.5239474963343811,-0.04008825025596049,1.0021895959906988,-0.16537868346442086,0.33218262437609547,-0.7590312945413134,3.824492664661767,0.18802891238331532,1.618928329270631,1.7763226939226555,-0.2492604414061187,0.8613062272321225
2,945
Response to peptide hormone
29
80
2.395799
0.016584
Q9HCD5,Q16836,P31751,Q15043,Q8WWQ0,Q6ZWJ1,P16435,P25054,Q08170,O75116,P35613,Q92922,P43490,Q9UQB8,O60763,P20020,P16220,P61026,Q13247,Q9Y266,Q05397,Q7L576,Q9H1E3,P42224,P61981,P22413,Q9BZF1,O75150,P62993
Processes and pathways
GO Biological process
msigdb_gobp
269,138,262,151,672,669,402,533,163,400,161,568,43,47,551,314,437,323,717,731,217,604,354,238,620,487,118,484,491
1662,1194,1047,1123,1794,703,551,400,484,862,1470,2229,1951,1342,1850,2202,2055,1129,437,402,2172,1296,314,487,533,2557,262,161,1134,1808,936,238,1859,43,2099,1715,2100,1138,1591,1539,2521,2377,1718,2721,323,620,491,1721,217,2459,163,2066,1549,2139,717,1262,1821,151,1027,1028,138,1364,669,604,806,672,1500,568,2030,1370,887,118,354,269,1701,1461,1040,47,731,2159
-0.14445310808685582,0.06384901323418327,0.14670037120281113,0.10530734984835549,-0.20728341801373437,0.352714297145243,0.49601692885848886,0.6589210414523182,0.5572126623575777,0.2499026019446144,-0.06092655176681376,-0.417912582552414,-0.2702763842063141,0.001537164702395684,-0.22826282947820883,-0.3967645192768137,-0.31236379292464844,0.10530734984835549,0.6182798801100748,0.6589210414523182,-0.37563575123099097,0.022324505727692668,0.8007319209650764,0.5572126623575777,0.5164299238420278,-0.6946624831235061,0.9016232814114782,1.2422720024056197,0.10530734984835549,-0.20728341801373437,0.20866925843125922,0.9821019275934442,-0.22826282947820883,2.860424771989179,-0.33343552863307785,-0.16537868346442086,-0.33343552863307785,0.10530734984835549,-0.10265492269446272,-0.08178207009671594,-0.6518579433658428,-0.5239474963343811,-0.16537868346442086,-0.9967910215997426,0.7805138743060999,0.4346904255440359,0.5572126623575777,-0.16537868346442086,1.0423270044122548,-0.587809634186986,1.2422720024056197,-0.31236379292464844,-0.08178207009671594,-0.35452613486786577,0.352714297145243,0.04309508514240472,-0.20728341801373437,1.2821160279306807,0.1673726504047501,0.1673726504047501,1.3815204900608,0.001537164702395684,0.3937322929558605,0.4551472654983724,0.2910734677256283,0.3937322929558605,-0.06092655176681376,0.49601692885848886,-0.29131079005371857,0.001537164702395684,0.2499026019446144,1.5992054978277717,0.7400374285311478,0.9016232814114782,-0.14445310808685582,-0.04008825025596049,0.1673726504047501,2.688128608527772,0.352714297145243,-0.35452613486786577
2,945
EF-hand domain [IPR002048]
7
43
2.391457
0.016782
Q9Y680,P80303,O43852,Q96AY3,P19174,Q14257,Q9NWM8
Sequence
InterPro Domain
interpro_domain
98,40,48,19,53,26,59
680,48,1124,824,2865,1667,1166,2538,792,2603,390,2787,1343,53,2056,831,557,2211,40,1820,451,1723,406,26,1602,139,1069,2276,2352,2028,2385,2145,19,258,2189,1842,1278,59,2902,1935,2155,730,98
0.37323082292864296,2.6113277676568396,0.10530734984835549,0.27049579609526114,-1.661197007707223,-0.14445310808685582,0.08458639893558295,-0.6732495316326513,0.2910734677256283,-0.7590312945413134,0.6792207642978566,-1.1935008981215134,0.001537164702395684,2.4765850676126675,-0.31236379292464844,0.27049579609526114,0.49601692885848886,-0.3967645192768137,2.91770423556765,-0.20728341801373437,0.597938284242163,-0.16537868346442086,0.6589210414523182,3.693333183718309,-0.10265492269446272,1.3616628687817531,0.14670037120281113,-0.4390800866390325,-0.5027007309924332,-0.29131079005371857,-0.5239474963343811,-0.35452613486786577,4.34572728753516,0.921762273203752,-0.37563575123099097,-0.20728341801373437,0.04309508514240472,2.438006058944413,-2.0722926032580373,-0.2492604414061187,-0.35452613486786577,0.352714297145243,1.835170758534991
2,945
Negative regulation of response to external stimulus
11
40
2.391092
0.016798
Q96G23,P80303,Q9UMX5,P55011,Q07021,P04439,P19174,P32119,Q9UIV1,P19474,P28070
Processes and pathways
GO Biological process
msigdb_gobp
72,40,103,232,178,175,53,210,117,186,31
701,2292,761,2201,552,2825,739,2746,175,2670,2913,53,186,1249,31,210,2130,1717,232,1022,941,40,405,178,1173,2140,1027,913,1368,1222,1879,1649,72,1692,784,1456,2614,117,103,290
0.352714297145243,-0.4602671791946553,0.3116357123478239,-0.3967645192768137,0.49601692885848886,-1.3701528148541127,0.33218262437609547,-1.0839642060391366,1.1824164060489466,-0.8883704331508439,-2.586040646525843,2.4765850676126675,1.142452277500605,0.04309508514240472,3.5053441140537633,1.062376874281129,-0.35452613486786577,-0.16537868346442086,1.0021895959906988,0.1673726504047501,0.20866925843125922,2.91770423556765,0.6589210414523182,1.1824164060489466,0.08458639893558295,-0.35452613486786577,0.1673726504047501,0.2292937886448734,0.001537164702395684,0.06384901323418327,-0.22826282947820883,-0.12354522852272666,2.166913142114243,-0.14445310808685582,0.3116357123478239,-0.04008825025596049,-0.7590312945413134,1.618928329270631,1.7763226939226555,0.8613062272321225
2,945
Regulation of mrna processing
28
77
2.390268
0.016836
P61978,P98175,Q07666,Q16629,P19338,Q08170,P52948,Q6PJT7,Q96E39,Q07021,Q8N684,P51114,P98179,Q9Y5S9,Q96PU8,P62995,Q13242,Q14011,Q13595,P22626,Q96MU7,Q9BWF3,P38159,P09651,Q15637,O75150,Q06787,O75494
Processes and pathways
GO Biological process
msigdb_gobp
134,515,273,407,532,163,295,428,173,178,444,439,61,465,330,197,77,93,346,224,368,239,109,359,363,484,254,127
968,1786,1793,1794,484,127,1092,863,359,1294,1670,933,1054,1345,532,1248,224,2092,1392,2373,935,109,1480,766,439,686,663,295,134,197,2878,871,515,61,1722,254,178,273,163,1492,872,1100,77,717,946,346,93,2245,1601,1726,363,407,1212,910,2275,644,2110,565,428,1407,2693,444,916,918,173,1834,368,330,2389,239,1154,695,755,2933,1238,733,465
0.18802891238331532,-0.20728341801373437,-0.20728341801373437,-0.20728341801373437,0.5572126623575777,1.4806368149043725,0.12601197226717611,0.2499026019446144,0.7197788815940095,0.022324505727692668,-0.14445310808685582,0.20866925843125922,0.14670037120281113,0.001537164702395684,0.5164299238420278,0.04309508514240472,1.0222645998514908,-0.33343552863307785,-0.01926704960112091,-0.5239474963343811,0.20866925843125922,1.6780316249499048,-0.06092655176681376,0.3116357123478239,0.6182798801100748,0.37323082292864296,0.3937322929558605,0.8411280257469278,1.4212012137589964,1.1224519125778383,-1.7972284475701508,0.2499026019446144,0.5368284738518867,2.399390495804993,-0.16537868346442086,0.921762273203752,1.1824164060489466,0.8814712891547717,1.2422720024056197,-0.06092655176681376,0.2499026019446144,0.12601197226717611,2.0891147678360613,0.352714297145243,0.20866925843125922,0.7400374285311478,1.8939254041622147,-0.417912582552414,-0.10265492269446272,-0.16537868346442086,0.7197788815940095,0.6589210414523182,0.06384901323418327,0.2292937886448734,-0.4390800866390325,0.4142187974298949,-0.33343552863307785,0.49601692885848886,0.6386074394794051,-0.01926704960112091,-0.9100071940702691,0.6182798801100748,0.2292937886448734,0.2292937886448734,1.202380291141655,-0.20728341801373437,0.7197788815940095,0.7805138743060999,-0.5239474963343811,0.9821019275934442,0.10530734984835549,0.37323082292864296,0.33218262437609547,-4.163068613869287,0.06384901323418327,0.352714297145243,0.597938284242163
2,945
Single stranded rna binding
12
36
2.383982
0.017126
P31943,P52597,O14979,Q6PJT7,P09651,Q07666,Q96SI9,Q06787,P23588,P51114,P07910,Q15056
Functions
GO Molecular function
msigdb_gomf
375,225,132,428,359,273,212,254,120,439,401,255
927,132,2121,636,1340,401,359,660,120,2092,1392,935,375,796,2003,439,225,2407,1722,1543,254,273,1492,1171,1172,255,428,457,806,1225,1324,1834,1326,212,2447,1940
0.20866925843125922,1.4212012137589964,-0.35452613486786577,0.4142187974298949,0.001537164702395684,0.6589210414523182,0.7197788815940095,0.3937322929558605,1.5794717175274886,-0.33343552863307785,-0.01926704960112091,0.20866925843125922,0.6995066854647584,0.2910734677256283,-0.29131079005371857,0.6182798801100748,1.0222645998514908,-0.5452144624387532,-0.16537868346442086,-0.08178207009671594,0.921762273203752,0.8814712891547717,-0.06092655176681376,0.08458639893558295,0.08458639893558295,0.921762273203752,0.6386074394794051,0.597938284242163,0.2910734677256283,0.06384901323418327,0.022324505727692668,-0.20728341801373437,0.022324505727692668,1.062376874281129,-0.5665017880289501,-0.2492604414061187
2,945
Zinc ion binding
28
126
2.38251
0.017195
Q5JRX3,Q8NCC3,P42892,Q03164,Q8NB78,Q9NZ08,Q16629,O95251,Q07864,Q8N4Q0,P55786,P43243,Q99536,P19474,Q86YP4,Q9NWT6,Q5VUA4,Q8N8N7,Q5JTZ9,Q99707,Q9UPP1,Q9NUD5,Q9BWF3,Q15637,Q9UIQ6,P22413,Q9HD42,Q05682
Functions
GO Molecular function
msigdb_gomf
266,7,264,13,21,22,407,155,162,44,45,424,189,186,459,204,456,75,350,477,223,234,239,363,116,487,385,492
1845,821,2890,1901,2427,2660,1386,1578,1579,155,1580,2786,2536,2825,2537,1668,2229,1342,1624,1850,2576,1129,1296,186,487,1199,2484,2432,1856,707,865,708,976,1803,2002,264,424,1135,559,765,1254,1589,1540,1355,2605,769,45,2506,1681,1819,13,2636,492,162,714,562,1360,493,1103,1104,1764,1211,1068,1148,363,1362,407,2070,2024,266,350,2665,456,2109,912,2788,2072,2112,1730,459,1368,44,2611,75,21,7,2308,1185,884,1832,1269,1606,674,1326,1836,2388,1924,189,1884,607,477,1982,2547,239,650,1738,385,234,204,2495,22,2629,2394,1617,116,2824,1781,1464,1782,223,1044,1083,2339,1284,926,1520
-0.22826282947820883,0.27049579609526114,-1.9572118375424268,-0.2492604414061187,-0.5665017880289501,-0.8667569312531026,-0.01926704960112091,-0.10265492269446272,-0.10265492269446272,1.262199946694982,-0.10265492269446272,-1.1935008981215134,-0.6732495316326513,-1.3701528148541127,-0.6732495316326513,-0.14445310808685582,-0.417912582552414,0.001537164702395684,-0.12354522852272666,-0.22826282947820883,-0.7160969742146781,0.10530734984835549,0.022324505727692668,1.142452277500605,0.5572126623575777,0.06384901323418327,-0.609138164405286,-0.5665017880289501,-0.22826282947820883,0.352714297145243,0.2499026019446144,0.352714297145243,0.18802891238331532,-0.20728341801373437,-0.29131079005371857,0.9016232814114782,0.6386074394794051,0.10530734984835549,0.49601692885848886,0.3116357123478239,0.04309508514240472,-0.10265492269446272,-0.08178207009671594,0.001537164702395684,-0.7590312945413134,0.3116357123478239,2.841314827134973,-0.6304875446399937,-0.14445310808685582,-0.20728341801373437,4.659667932546476,-0.8020539598800626,0.5572126623575777,1.2422720024056197,0.352714297145243,0.49601692885848886,0.001537164702395684,0.5572126623575777,0.12601197226717611,0.12601197226717611,-0.18632207833549766,0.06384901323418327,0.14670037120281113,0.10530734984835549,0.7197788815940095,0.001537164702395684,0.6589210414523182,-0.31236379292464844,-0.29131079005371857,0.9016232814114782,0.7400374285311478,-0.8667569312531026,0.597938284242163,-0.33343552863307785,0.2292937886448734,-1.1935008981215134,-0.31236379292464844,-0.33343552863307785,-0.16537868346442086,0.597938284242163,0.001537164702395684,2.860424771989179,-0.7590312945413134,2.1085789946182025,4.01126221185754,5.6091396582180515,-0.4602671791946553,0.08458639893558295,0.2499026019446144,-0.20728341801373437,0.04309508514240472,-0.10265492269446272,0.3937322929558605,0.022324505727692668,-0.20728341801373437,-0.5239474963343811,-0.2492604414061187,1.142452277500605,-0.22826282947820883,0.4551472654983724,0.5775825719273033,-0.2702763842063141,-0.6732495316326513,0.9821019275934442,0.4142187974298949,-0.16537868346442086,0.6995066854647584,1.0021895959906988,1.1024392652871489,-0.609138164405286,3.824492664661767,-0.7805314905603624,-0.5239474963343811,-0.10265492269446272,1.618928329270631,-1.3479736939343891,-0.18632207833549766,-0.04008825025596049,-0.18632207833549766,1.0423270044122548,0.1673726504047501,0.14670037120281113,-0.4814740099977851,0.04309508514240472,0.2292937886448734,-0.06092655176681376
2,945
Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps
9
16
2.378282
0.017394
Q07065,Q15293,O76024,P14314,Q5JRA6,O43852,P07237,Q13217,P14625
Processes and pathways
Reactome Pathways
msigdb_reactome
233,139,76,390,172,48,418,241,468
48,76,418,1851,390,468,1854,1820,233,1723,241,951,139,172,498,2472
2.6113277676568396,2.0891147678360613,0.6386074394794051,-0.22826282947820883,0.6792207642978566,0.5775825719273033,-0.22826282947820883,-0.20728341801373437,1.0021895959906988,-0.16537868346442086,0.9620015287859891,0.20866925843125922,1.3616628687817531,1.202380291141655,0.5572126623575777,-0.587809634186986
2,945
Rna splicing
62
203
2.366824
0.017941
P31943,O75934,Q99459,P67809,P61978,Q9Y4C8,Q15233,P55795,P98175,Q07666,Q8N163,Q16629,P52272,P07910,P19338,Q08170,Q8WWY3,Q8IWZ8,O43390,P52948,Q96E39,Q07021,Q9ULX6,Q92804,P51991,Q14562,Q96PK6,P51114,P98179,Q9Y5S9,Q96PU8,Q96QD8,P31942,P62995,Q5BKZ1,Q9Y2W2,Q07955,Q9UJV9,O43290,Q13242,P23246,Q13123,O60506,Q96FV9,Q14011,Q92620,Q13595,P52597,P22626,Q96MU7,Q96DF8,Q9BWF3,P38159,P09651,Q15637,Q13435,Q8WVV9,P41223,P35637,Q15459,Q06787,O75494
Processes and pathways
GO Biological process
msigdb_gobp
375,374,523,129,134,527,517,514,515,273,277,407,535,401,532,163,432,566,169,295,173,178,573,180,182,56,188,439,61,465,330,66,195,197,198,464,324,462,447,77,333,453,215,476,93,229,346,225,224,368,367,239,109,359,363,494,242,488,115,518,254,127
1380,1786,1084,1787,1428,1790,576,447,169,2648,1992,1005,1382,2400,636,2650,215,682,1901,1006,823,127,1125,1050,374,1051,1387,2167,401,930,1092,863,359,1167,1294,660,1670,2171,933,1054,532,224,333,2344,2092,1392,2373,617,935,195,375,115,109,1585,2003,488,1020,981,1480,439,686,182,535,225,663,295,1438,1256,514,2241,134,2184,1680,1142,2793,1440,2663,197,129,2878,871,515,61,1722,2642,2304,254,178,273,324,163,1492,872,1064,835,1100,562,453,2018,77,2139,717,494,2410,946,346,1263,93,1822,1601,56,1174,1764,1725,1765,517,1766,518,363,407,1176,910,2275,2070,198,2920,2412,876,1729,1071,912,1873,1407,1215,2072,1267,2703,566,1686,805,2693,277,2251,1185,1831,242,432,2827,1225,229,180,918,1226,783,2584,367,2566,173,1834,476,694,1412,368,2388,188,330,66,2389,523,1775,1608,239,2334,1154,848,1986,2447,2192,1700,1702,1703,1331,1332,2933,462,1236,788,573,1238,1937,2422,733,464,1240,2697,1619,634,613,2200,2084,527,2812,465
-0.01926704960112091,-0.20728341801373437,0.12601197226717611,-0.20728341801373437,-0.04008825025596049,-0.20728341801373437,0.4755894045159319,0.597938284242163,1.202380291141655,-0.845166484742484,-0.29131079005371857,0.1673726504047501,-0.01926704960112091,-0.5452144624387532,0.4142187974298949,-0.845166484742484,1.0423270044122548,0.37323082292864296,-0.2492604414061187,0.1673726504047501,0.27049579609526114,1.4806368149043725,0.10530734984835549,0.14670037120281113,0.6995066854647584,0.14670037120281113,-0.01926704960112091,-0.37563575123099097,0.6589210414523182,0.20866925843125922,0.12601197226717611,0.2499026019446144,0.7197788815940095,0.08458639893558295,0.022324505727692668,0.3937322929558605,-0.14445310808685582,-0.37563575123099097,0.20866925843125922,0.14670037120281113,0.5164299238420278,1.0222645998514908,0.7602824013383189,-0.5027007309924332,-0.33343552863307785,-0.01926704960112091,-0.5239474963343811,0.4346904255440359,0.20866925843125922,1.1224519125778383,0.6995066854647584,1.618928329270631,1.6780316249499048,-0.10265492269446272,-0.29131079005371857,0.5572126623575777,0.1673726504047501,0.18802891238331532,-0.06092655176681376,0.6182798801100748,0.37323082292864296,1.1624404216515005,0.5164299238420278,1.0222645998514908,0.3937322929558605,0.8411280257469278,-0.04008825025596049,0.04309508514240472,0.5368284738518867,-0.417912582552414,1.4212012137589964,-0.37563575123099097,-0.14445310808685582,0.10530734984835549,-1.2154867397644784,-0.04008825025596049,-0.8667569312531026,1.1224519125778383,1.4410244250244986,-1.7972284475701508,0.2499026019446144,0.5368284738518867,2.399390495804993,-0.16537868346442086,-0.8235988933073602,-0.4602671791946553,0.921762273203752,1.1824164060489466,0.8814712891547717,0.7805138743060999,1.2422720024056197,-0.06092655176681376,0.2499026019446144,0.14670037120281113,0.27049579609526114,0.12601197226717611,0.49601692885848886,0.597938284242163,-0.29131079005371857,2.0891147678360613,-0.35452613486786577,0.352714297145243,0.5572126623575777,-0.5452144624387532,0.20866925843125922,0.7400374285311478,0.04309508514240472,1.8939254041622147,-0.20728341801373437,-0.10265492269446272,2.4573001148610345,0.08458639893558295,-0.18632207833549766,-0.16537868346442086,-0.18632207833549766,0.5368284738518867,-0.18632207833549766,0.5368284738518867,0.7197788815940095,0.6589210414523182,0.08458639893558295,0.2292937886448734,-0.4390800866390325,-0.31236379292464844,1.1224519125778383,-2.9905583029480534,-0.5452144624387532,0.2499026019446144,-0.16537868346442086,0.14670037120281113,0.2292937886448734,-0.22826282947820883,-0.01926704960112091,0.06384901323418327,-0.31236379292464844,0.04309508514240472,-0.9316674210504035,0.49601692885848886,-0.14445310808685582,0.2910734677256283,-0.9100071940702691,0.8814712891547717,-0.417912582552414,0.08458639893558295,-0.20728341801373437,0.9620015287859891,0.6386074394794051,-1.3701528148541127,0.06384901323418327,1.0222645998514908,1.1824164060489466,0.2292937886448734,0.06384901323418327,0.3116357123478239,-0.7160969742146781,0.7197788815940095,-0.6946624831235061,1.202380291141655,-0.20728341801373437,0.5775825719273033,0.37323082292864296,-0.01926704960112091,0.7197788815940095,-0.5239474963343811,1.142452277500605,0.7805138743060999,2.3607380919625607,-0.5239474963343811,0.5368284738518867,-0.18632207833549766,-0.10265492269446272,0.9821019275934442,-0.4814740099977851,0.10530734984835549,0.27049579609526114,-0.2702763842063141,-0.5665017880289501,-0.37563575123099097,-0.14445310808685582,-0.14445310808685582,-0.14445310808685582,0.022324505727692668,0.022324505727692668,-4.163068613869287,0.597938284242163,0.06384901323418327,0.3116357123478239,0.49601692885848886,0.06384901323418327,-0.2492604414061187,-0.5452144624387532,0.352714297145243,0.597938284242163,0.06384901323418327,-0.9100071940702691,-0.10265492269446272,0.4346904255440359,0.4551472654983724,-0.37563575123099097,-0.31236379292464844,0.5368284738518867,-1.2595390174555432,0.597938284242163
2,945
Pleckstrin homology domain [IPR001849]
8
23
2.360244
0.018263
O15020,P31751,Q14155,P19174,Q9BZF1,Q9UJF2,Q96TA1,O75116
Sequence
InterPro Domain
interpro_domain
372,262,171,53,118,357,88,400
1047,372,400,53,1347,262,1058,440,1065,1262,171,1108,2445,1606,1503,1504,810,88,1188,118,2696,1929,357
0.14670037120281113,0.6995066854647584,0.6589210414523182,2.4765850676126675,0.001537164702395684,0.9016232814114782,0.14670037120281113,0.6182798801100748,0.14670037120281113,0.04309508514240472,1.202380291141655,0.12601197226717611,-0.5665017880289501,-0.10265492269446272,-0.06092655176681376,-0.06092655176681376,0.2910734677256283,1.9525878342172756,0.08458639893558295,1.5992054978277717,-0.9100071940702691,-0.2492604414061187,0.7400374285311478
2,945
Negative regulation of rna splicing
6
15
2.353562
0.018594
Q08170,P61978,P38159,Q13242,Q07021,O75494
Processes and pathways
GO Biological process
msigdb_gobp
163,134,109,77,178,127
1786,127,224,2092,1392,109,134,2184,515,178,163,1100,77,717,407
-0.20728341801373437,1.4806368149043725,1.0222645998514908,-0.33343552863307785,-0.01926704960112091,1.6780316249499048,1.4212012137589964,-0.37563575123099097,0.5368284738518867,1.1824164060489466,1.2422720024056197,0.12601197226717611,2.0891147678360613,0.352714297145243,0.6589210414523182
2,945
Abnormal vascular physiology
9
45
2.353406
0.018602
P03886,O15460,P00403,P42224,O75844,Q9NZ08,Q9NWM8,Q14739,O96000
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
2,100,166,238,80,22,59,29,63
100,702,2201,1996,80,974,63,166,739,790,2,2746,1668,2767,1851,1054,794,2372,827,487,1435,707,2057,2001,641,238,1716,2887,2269,1022,1143,404,664,2931,1965,29,255,1768,2276,2278,1512,59,22,1617,2647
1.7763226939226555,0.352714297145243,-0.3967645192768137,-0.29131079005371857,2.0501568052051606,0.18802891238331532,2.3800689170256426,1.2223321368163933,0.33218262437609547,0.2910734677256283,7.077162194942315,-1.0839642060391366,-0.14445310808685582,-1.1277013965550577,-0.22826282947820883,0.14670037120281113,0.2910734677256283,-0.5239474963343811,0.27049579609526114,0.5572126623575777,-0.04008825025596049,0.352714297145243,-0.31236379292464844,-0.29131079005371857,0.4142187974298949,0.9821019275934442,-0.16537868346442086,-1.9113655148381163,-0.4390800866390325,0.1673726504047501,0.10530734984835549,0.6589210414523182,0.3937322929558605,-3.8168269043326535,-0.2702763842063141,3.655794126757704,0.921762273203752,-0.18632207833549766,-0.4390800866390325,-0.4390800866390325,-0.06092655176681376,2.438006058944413,3.824492664661767,-0.10265492269446272,-0.8235988933073602
2,945
Cellular response to peptide
23
66
2.346994
0.018926
Q9HCD5,P31751,Q9UNS1,Q15043,Q8WWQ0,P16435,O75116,P25054,Q92922,P43490,Q9UQB8,O60763,P20020,P61026,P08670,Q05397,Q7L576,Q9H1E3,P42224,P61981,P22413,Q9BZF1,P62993
Processes and pathways
GO Biological process
msigdb_gobp
269,262,547,151,672,402,400,533,568,43,47,551,314,323,205,217,604,354,238,620,487,118,491
1662,1047,1123,1794,703,551,400,1668,1470,2229,205,1342,2202,2055,1129,402,2172,1296,314,487,533,2557,262,1134,936,238,43,2099,1715,2100,1591,1539,2521,2377,2721,323,620,1639,491,1721,2348,217,2459,2066,2139,1262,151,1028,1364,669,604,672,1500,568,2030,1606,1370,118,354,269,1461,1421,1936,547,47,2159
-0.14445310808685582,0.14670037120281113,0.10530734984835549,-0.20728341801373437,0.352714297145243,0.49601692885848886,0.6589210414523182,-0.14445310808685582,-0.06092655176681376,-0.417912582552414,1.0824142734467934,0.001537164702395684,-0.3967645192768137,-0.31236379292464844,0.10530734984835549,0.6589210414523182,-0.37563575123099097,0.022324505727692668,0.8007319209650764,0.5572126623575777,0.5164299238420278,-0.6946624831235061,0.9016232814114782,0.10530734984835549,0.20866925843125922,0.9821019275934442,2.860424771989179,-0.33343552863307785,-0.16537868346442086,-0.33343552863307785,-0.10265492269446272,-0.08178207009671594,-0.6518579433658428,-0.5239474963343811,-0.9967910215997426,0.7805138743060999,0.4346904255440359,-0.12354522852272666,0.5572126623575777,-0.16537868346442086,-0.5027007309924332,1.0423270044122548,-0.587809634186986,-0.31236379292464844,-0.35452613486786577,0.04309508514240472,1.2821160279306807,0.1673726504047501,0.001537164702395684,0.3937322929558605,0.4551472654983724,0.3937322929558605,-0.06092655176681376,0.49601692885848886,-0.29131079005371857,-0.10265492269446272,0.001537164702395684,1.5992054978277717,0.7400374285311478,0.9016232814114782,-0.04008825025596049,-0.01926704960112091,-0.2492604414061187,0.5164299238420278,2.688128608527772,-0.35452613486786577
2,945
Alcohol biosynthetic process
6
35
2.344545
0.01905
P00374,Q15392,P37268,P61457,P48449,Q14739
Processes and pathways
GO Biological process
msigdb_gobp
1,5,12,86,91,29
2659,1788,1286,825,1008,1,2719,2773,2746,2556,1852,2235,402,2172,271,12,1202,91,1059,1485,86,2063,405,2929,2524,29,2350,5,2653,2847,1028,101,2682,2685,2628
-0.8667569312531026,-0.20728341801373437,0.022324505727692668,0.27049579609526114,0.1673726504047501,7.448017023011698,-0.9967910215997426,-1.1496084842326584,-1.0839642060391366,-0.6946624831235061,-0.22826282947820883,-0.417912582552414,0.6589210414523182,-0.37563575123099097,0.8814712891547717,4.770037134790452,0.06384901323418327,1.9134897350999418,0.14670037120281113,-0.06092655176681376,1.9525878342172756,-0.31236379292464844,0.6589210414523182,-3.571580495971794,-0.6518579433658428,3.655794126757704,-0.5027007309924332,5.735788324107087,-0.845166484742484,-1.5262302338877283,0.1673726504047501,1.7763226939226555,-0.8883704331508439,-0.8883704331508439,-0.7805314905603624
2,945
Amide binding
16
103
2.33743
0.019417
Q8WTV0,P00374,P24390,Q9Y680,O15212,Q15392,Q9H845,P35610,P55786,P04439,Q96AY3,Q13451,Q9UIQ6,Q9NZ08,P62942,Q02790
Functions
GO Molecular function
msigdb_gomf
32,1,64,98,160,5,70,107,45,175,19,83,116,22,25,58
2397,735,192,592,1467,2892,2843,2857,160,509,1992,2772,2452,2051,1007,1,739,175,2631,2830,2932,1197,596,419,2575,2832,1129,2846,1476,1016,2592,64,1131,707,2820,2295,1857,107,1536,1632,1714,1808,264,2593,2662,1587,1716,1137,2101,1590,1139,1303,2133,295,45,1542,2010,1024,2378,25,771,582,801,907,58,2776,2699,83,2542,1211,949,2525,5,779,2788,1451,32,1322,1833,19,783,1270,2860,2031,2332,888,1609,383,1455,1277,813,70,2598,2905,22,2599,2040,298,116,2885,613,2937,98
-0.5452144624387532,0.33218262437609547,1.1224519125778383,0.4551472654983724,-0.06092655176681376,-1.9801752339439305,-1.5038429397324582,-1.6160871999173578,1.2422720024056197,0.5368284738518867,-0.29131079005371857,-1.1496084842326584,-0.587809634186986,-0.31236379292464844,0.1673726504047501,7.448017023011698,0.33218262437609547,1.1824164060489466,-0.8020539598800626,-1.3923607141779688,-3.890742390654541,0.06384901323418327,0.4551472654983724,0.6386074394794051,-0.7160969742146781,-1.3923607141779688,0.10530734984835549,-1.5262302338877283,-0.06092655176681376,0.1673726504047501,-0.7375531840373677,2.3607380919625607,0.10530734984835549,0.352714297145243,-1.3479736939343891,-0.4602671791946553,-0.22826282947820883,1.7173799770740772,-0.08178207009671594,-0.12354522852272666,-0.16537868346442086,-0.20728341801373437,0.9016232814114782,-0.7375531840373677,-0.8667569312531026,-0.10265492269446272,-0.16537868346442086,0.10530734984835549,-0.33343552863307785,-0.10265492269446272,0.10530734984835549,0.022324505727692668,-0.35452613486786577,0.8411280257469278,2.841314827134973,-0.08178207009671594,-0.29131079005371857,0.1673726504047501,-0.5239474963343811,3.768324465880385,0.3116357123478239,0.4755894045159319,0.2910734677256283,0.2292937886448734,2.438006058944413,-1.1496084842326584,-0.9316674210504035,1.9916454712619938,-0.6732495316326513,0.06384901323418327,0.20866925843125922,-0.6518579433658428,5.735788324107087,0.3116357123478239,-1.1935008981215134,-0.04008825025596049,3.5053441140537633,0.022324505727692668,-0.20728341801373437,4.34572728753516,0.3116357123478239,0.04309508514240472,-1.6386272017792467,-0.29131079005371857,-0.4814740099977851,0.2499026019446144,-0.10265492269446272,0.6995066854647584,-0.04008825025596049,0.04309508514240472,0.2910734677256283,2.2057541946060866,-0.7375531840373677,-2.2112400397120173,3.824492664661767,-0.7375531840373677,-0.29131079005371857,0.8411280257469278,1.618928329270631,-1.888482982023875,0.4551472654983724,-4.814458862998807,1.835170758534991
2,945
Negative regulation of mrna splicing via spliceosome
6
14
2.331888
0.019707
Q08170,P61978,P38159,Q13242,Q07021,O75494
Processes and pathways
GO Biological process
msigdb_gobp
163,134,109,77,178,127
1786,127,224,2092,1392,109,134,515,178,163,1100,77,717,407
-0.20728341801373437,1.4806368149043725,1.0222645998514908,-0.33343552863307785,-0.01926704960112091,1.6780316249499048,1.4212012137589964,0.5368284738518867,1.1824164060489466,1.2422720024056197,0.12601197226717611,2.0891147678360613,0.352714297145243,0.6589210414523182
2,945
Cholesterol metabolism with bloch and kandutschrussell pathways
6
24
2.329501
0.019833
Q16850,Q15392,P35610,P37268,P48449,Q14739
Processes and pathways
WikiPathways
msigdb_wp
101,5,107,12,91,29
819,2313,825,1848,738,2773,2235,2095,107,12,91,1716,2063,405,2524,1313,29,2350,5,2653,2847,101,213,2628
0.27049579609526114,-0.4814740099977851,0.27049579609526114,-0.22826282947820883,0.33218262437609547,-1.1496084842326584,-0.417912582552414,-0.33343552863307785,1.7173799770740772,4.770037134790452,1.9134897350999418,-0.16537868346442086,-0.31236379292464844,0.6589210414523182,-0.6518579433658428,0.022324505727692668,3.655794126757704,-0.5027007309924332,5.735788324107087,-0.845166484742484,-1.5262302338877283,1.7763226939226555,1.062376874281129,-0.7805314905603624
2,945
Abnormal circulating nitrogen compound concentration
7
50
2.328653
0.019877
O43772,Q9H845,P35610,P11310,Q9Y619,P61457,Q6NUQ1
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
34,70,107,11,50,86,28
1193,34,1901,1339,2053,1127,1746,2454,2830,1243,2230,1951,826,932,11,1346,828,1477,2519,1856,107,1673,1808,231,1677,1137,2869,982,1960,2651,86,1024,2722,492,908,688,2643,138,28,1152,2860,2074,2745,70,2765,1512,2224,1933,1935,50
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2,945
Transcription
69
283
2.325505
0.020045
Q96IZ0,Q99459,P67809,Q9H0D6,P61978,Q15233,O14979,Q5QJE6,Q9HCD5,O60885,Q03164,Q8TAQ2,Q9GZT3,Q9UNS1,Q07666,Q8N163,Q8NB78,Q9UBU8,Q99417,Q96I24,O95251,P53999,P49750,O75155,Q9BRG1,Q8NEY8,Q6PD62,Q9H1I8,Q92922,Q07021,Q9NYF8,Q13547,Q14241,Q96PK6,O00625,P16220,Q9Y6J9,O00411,Q5BKZ1,Q86YP4,Q9NWT6,P52434,Q5VUA4,O60716,Q9H501,Q96T58,P23246,P29692,P61457,Q14103,Q9NX63,Q96FV9,Q8N9N2,Q8IZL8,Q9UBK9,Q9UPP1,Q01844,P12956,Q9NPA8,Q9UHR5,P13984,P38159,P42224,Q96AE4,Q15637,P41223,Q9UIV1,Q9HD42,Q13330
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
128,523,129,395,134,517,132,267,269,511,13,539,146,547,273,277,21,278,411,410,155,536,157,280,434,431,565,167,568,178,306,54,319,188,311,437,466,310,198,459,204,322,456,449,340,208,333,334,86,335,355,476,220,352,95,223,226,343,506,235,106,109,238,366,363,488,117,385,493
2288,735,968,310,1786,927,311,820,2399,1787,1428,1706,132,970,1195,855,1789,2120,702,1382,856,2650,449,682,2590,511,280,928,2687,823,2428,1339,155,2536,1290,1905,1796,1165,1668,2403,1342,1294,343,1530,106,437,684,639,933,706,1345,793,1855,2371,1095,1798,1199,333,579,1348,2484,1097,2557,1800,2094,334,2000,2001,1804,978,109,1674,1134,488,238,1056,2539,1589,157,905,982,767,322,536,1485,870,86,2013,134,2407,1681,129,1598,1143,713,2652,2321,772,1722,226,13,1308,1545,984,664,178,273,1492,1761,1309,1682,1762,1100,2323,1914,1171,986,2541,2018,987,1360,493,1310,1144,54,946,1101,335,2245,319,1601,1103,1174,1104,1764,2884,2610,584,517,2867,2489,2464,1726,363,1966,1362,666,1403,1027,2442,2761,2275,198,267,456,2249,1178,1447,2110,565,2383,2328,1407,1109,1769,1180,2072,878,1320,459,841,2528,1076,605,2250,1770,1368,352,277,1218,916,220,21,1603,431,539,671,624,722,884,1225,1688,2467,2512,918,568,1226,2468,366,2852,476,410,128,1373,751,188,1186,2770,208,2753,1924,411,523,1980,2332,1982,2114,434,1607,1001,1652,1888,1562,1653,146,395,2597,167,1455,695,1986,340,1511,965,1037,2803,269,627,1456,2192,2193,385,506,891,1930,609,1457,2081,755,1613,204,2614,355,306,95,1003,278,1515,235,2933,1617,117,2043,1236,2045,573,547,1782,223,1844,2571,2422,851,2364,733,2479,924,2117,1334,2050,2118,1122,466
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2,945
Hedgehog ligand biogenesis
12
41
2.323968
0.020127
P25787,P60900,Q86TM6,P28072,Q99436,Q9GZP9,P20618,P07237,P51665,O00231,P49721,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
3,196,520,69,504,369,261,418,561,550,469,31
550,2398,2163,1523,1337,1622,418,1672,261,1249,3,1533,2483,1631,31,69,829,2318,1809,2578,2505,469,561,1306,1679,196,580,1863,1638,1595,2244,1210,2750,1265,520,2279,504,1114,369,1237,1568
0.49601692885848886,-0.5452144624387532,-0.37563575123099097,-0.08178207009671594,0.001537164702395684,-0.12354522852272666,0.6386074394794051,-0.14445310808685582,0.9016232814114782,0.04309508514240472,6.86435802761024,-0.08178207009671594,-0.609138164405286,-0.12354522852272666,3.5053441140537633,2.2639439873853995,0.27049579609526114,-0.4814740099977851,-0.20728341801373437,-0.7160969742146781,-0.6304875446399937,0.5775825719273033,0.49601692885848886,0.022324505727692668,-0.14445310808685582,1.1224519125778383,0.4755894045159319,-0.22826282947820883,-0.12354522852272666,-0.10265492269446272,-0.417912582552414,0.06384901323418327,-1.0839642060391366,0.04309508514240472,0.5368284738518867,-0.4390800866390325,0.5572126623575777,0.12601197226717611,0.7197788815940095,0.06384901323418327,-0.08178207009671594
2,945
Negative regulation of mrna catabolic process
12
25
2.321461
0.020262
P11940,P67809,Q92804,P98175,Q99729,Q13151,P35637,Q06787,Q14103,O60506,Q14011,P07910
Processes and pathways
GO Biological process
msigdb_gobp
660,129,180,515,209,563,115,254,335,215,93,401
1193,215,1384,401,660,115,980,129,515,1722,254,1492,2018,563,93,335,988,1027,1030,1878,180,209,812,1002,733
0.06384901323418327,1.0423270044122548,-0.01926704960112091,0.6589210414523182,0.3937322929558605,1.618928329270631,0.18802891238331532,1.4410244250244986,0.5368284738518867,-0.16537868346442086,0.921762273203752,-0.06092655176681376,-0.29131079005371857,0.49601692885848886,1.8939254041622147,0.7602824013383189,0.18802891238331532,0.1673726504047501,0.1673726504047501,-0.22826282947820883,1.1824164060489466,1.0824142734467934,0.2910734677256283,0.18802891238331532,0.352714297145243
2,945
Response to toxic substance
6
49
2.317613
0.02047
Q15165,P00374,P07099,Q13242,Q04656,O95831
Processes and pathways
GO Biological process
msigdb_gobp
0,1,4,77,148,89
467,1790,510,2572,2650,89,1,1529,2690,2631,929,4,1433,1293,2602,2576,2203,2846,1906,2206,2820,2373,1954,685,210,512,272,2800,2002,1715,150,148,2460,583,77,2664,0,803,1920,458,2466,1732,522,674,2682,888,1926,2310,2423
0.5775825719273033,-0.20728341801373437,0.5368284738518867,-0.7160969742146781,-0.845166484742484,1.9330438639514882,7.448017023011698,-0.08178207009671594,-0.9100071940702691,-0.8020539598800626,0.20866925843125922,6.31148905834133,-0.04008825025596049,0.022324505727692668,-0.7590312945413134,-0.7160969742146781,-0.3967645192768137,-1.5262302338877283,-0.2492604414061187,-0.3967645192768137,-1.3479736939343891,-0.5239474963343811,-0.2702763842063141,0.37323082292864296,1.062376874281129,0.5368284738518867,0.8814712891547717,-1.2374993562115237,-0.29131079005371857,-0.16537868346442086,1.2821160279306807,1.3020203038267055,-0.587809634186986,0.4755894045159319,2.0891147678360613,-0.8667569312531026,7.623940234694683,0.2910734677256283,-0.2492604414061187,0.597938284242163,-0.587809634186986,-0.16537868346442086,0.5368284738518867,0.3937322929558605,-0.8883704331508439,0.2499026019446144,-0.2492604414061187,-0.4602671791946553,-0.5452144624387532
2,945
Abnormal femoral neck head morphology
7
40
2.307915
0.021004
Q9Y487,O75844,Q9Y619,Q96AY3,O95831,Q6NUQ1,Q14739
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
140,80,50,19,89,28,29
2785,2401,2089,388,80,89,790,1997,2889,2372,487,2176,2094,2266,2520,979,799,232,2010,148,29,1724,1104,28,2817,1828,1228,19,1372,2282,543,1375,2532,1987,445,1192,140,2480,465,50
-1.1935008981215134,-0.5452144624387532,-0.33343552863307785,0.6792207642978566,2.0501568052051606,1.9330438639514882,0.2910734677256283,-0.29131079005371857,-1.9342751994429657,-0.5239474963343811,0.5572126623575777,-0.37563575123099097,-0.33343552863307785,-0.4390800866390325,-0.6518579433658428,0.18802891238331532,0.2910734677256283,1.0021895959906988,-0.29131079005371857,1.3020203038267055,3.655794126757704,-0.16537868346442086,0.12601197226717611,3.6745672923672013,-1.3037005802478918,-0.20728341801373437,0.06384901323418327,4.34572728753516,0.001537164702395684,-0.4390800866390325,0.5164299238420278,0.001537164702395684,-0.6518579433658428,-0.2702763842063141,0.6182798801100748,0.08458639893558295,1.3616628687817531,-0.587809634186986,0.597938284242163,2.592105567404909
2,945
Striated muscle cell differentiation
6
41
2.306925
0.021059
P67809,P11310,Q9H7B4,O75844,Q13547,Q96TA1
Processes and pathways
GO Biological process
msigdb_gobp
129,11,14,80,54,88
448,1847,80,972,1007,790,1091,929,1292,530,11,1852,1343,1854,707,742,1859,1675,1591,2299,129,1722,664,986,54,1965,2884,2638,1027,2679,1975,2356,88,887,383,1278,14,1190,199,2874,1938
0.597938284242163,-0.22826282947820883,2.0501568052051606,0.18802891238331532,0.1673726504047501,0.2910734677256283,0.12601197226717611,0.20866925843125922,0.022324505727692668,0.5164299238420278,4.9168542761704375,-0.22826282947820883,0.001537164702395684,-0.22826282947820883,0.352714297145243,0.33218262437609547,-0.22826282947820883,-0.14445310808685582,-0.10265492269446272,-0.4602671791946553,1.4410244250244986,-0.16537868346442086,0.3937322929558605,0.18802891238331532,2.4765850676126675,-0.2702763842063141,-1.8656278024761768,-0.8020539598800626,0.1673726504047501,-0.8883704331508439,-0.2702763842063141,-0.5027007309924332,1.9525878342172756,0.2499026019446144,0.6995066854647584,0.04309508514240472,4.62282865259948,0.08458639893558295,1.1224519125778383,-1.751769488181549,-0.2492604414061187
2,945
Weight loss
14
67
2.301685
0.021353
O00330,Q01844,O15460,Q99720,P35610,P11310,P42892,O75844,Q13423,P35637,Q04656,Q9NZ08,P21912,Q6UN15
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
193,226,100,8,107,11,264,80,112,115,148,22,119,125
193,2851,100,594,2640,80,1011,1905,739,790,2746,1668,763,1245,2932,1014,530,11,706,827,119,1628,2519,707,1750,107,115,272,1673,1955,2939,1134,2486,937,264,902,1716,982,1756,1397,2062,226,2017,537,148,1443,1360,112,774,718,1314,2676,2643,2110,125,1497,2564,784,2513,8,2391,1375,1378,22,2599,2225,1424
1.1224519125778383,-1.5710975994835399,1.7763226939226555,0.4551472654983724,-0.8235988933073602,2.0501568052051606,0.1673726504047501,-0.2492604414061187,0.33218262437609547,0.2910734677256283,-1.0839642060391366,-0.14445310808685582,0.3116357123478239,0.04309508514240472,-3.890742390654541,0.1673726504047501,0.5164299238420278,4.9168542761704375,0.352714297145243,0.27049579609526114,1.5794717175274886,-0.12354522852272666,-0.6518579433658428,0.352714297145243,-0.18632207833549766,1.7173799770740772,1.618928329270631,0.8814712891547717,-0.14445310808685582,-0.2702763842063141,-5.399061502057131,0.10530734984835549,-0.609138164405286,0.20866925843125922,0.9016232814114782,0.2292937886448734,-0.16537868346442086,0.18802891238331532,-0.18632207833549766,-0.01926704960112091,-0.31236379292464844,1.0222645998514908,-0.29131079005371857,0.5164299238420278,1.3020203038267055,-0.04008825025596049,0.001537164702395684,1.6583413438014383,0.3116357123478239,0.352714297145243,0.022324505727692668,-0.8883704331508439,-0.8235988933073602,-0.33343552863307785,1.5004260995112062,-0.06092655176681376,-0.6946624831235061,0.3116357123478239,-0.6304875446399937,5.500372154885624,-0.5239474963343811,0.001537164702395684,0.001537164702395684,3.824492664661767,-0.7375531840373677,-0.3967645192768137,-0.01926704960112091
2,945
Abnormal circulating hormone concentration
13
78
2.301512
0.021363
O00330,Q92620,Q12768,Q07864,Q969G3,Q9UMX1,Q4J6C6,Q16836,Q03164,O75844,Q13423,P21912,Q06787
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
193,229,130,162,257,260,137,138,13,80,112,119,254
1991,193,1047,1706,576,2648,1945,1468,2401,2089,1050,2688,80,1163,1387,2053,790,1668,1014,1624,530,402,827,119,1750,262,1803,1806,1955,2486,1808,1138,2580,2008,982,1593,2009,1140,712,2010,1594,1208,2722,2017,13,254,162,130,1549,112,1821,1067,2637,690,138,137,2110,1873,1828,1111,1182,2251,672,432,229,2188,257,1836,1455,1701,2361,850,1378,1703,1040,758,260,1192
-0.29131079005371857,1.1224519125778383,0.14670037120281113,-0.16537868346442086,0.4755894045159319,-0.845166484742484,-0.2702763842063141,-0.06092655176681376,-0.5452144624387532,-0.33343552863307785,0.14670037120281113,-0.9100071940702691,2.0501568052051606,0.08458639893558295,-0.01926704960112091,-0.31236379292464844,0.2910734677256283,-0.14445310808685582,0.1673726504047501,-0.12354522852272666,0.5164299238420278,0.6589210414523182,0.27049579609526114,1.5794717175274886,-0.18632207833549766,0.9016232814114782,-0.20728341801373437,-0.20728341801373437,-0.2702763842063141,-0.609138164405286,-0.20728341801373437,0.10530734984835549,-0.7160969742146781,-0.29131079005371857,0.18802891238331532,-0.10265492269446272,-0.29131079005371857,0.10530734984835549,0.352714297145243,-0.29131079005371857,-0.10265492269446272,0.06384901323418327,-0.9967910215997426,-0.29131079005371857,4.659667932546476,0.921762273203752,1.2422720024056197,1.4410244250244986,-0.08178207009671594,1.6583413438014383,-0.20728341801373437,0.14670037120281113,-0.8020539598800626,0.37323082292864296,1.3815204900608,1.4013665868313239,-0.33343552863307785,-0.22826282947820883,-0.20728341801373437,0.12601197226717611,0.08458639893558295,-0.417912582552414,0.3937322929558605,0.6386074394794051,1.0222645998514908,-0.37563575123099097,0.921762273203752,-0.20728341801373437,-0.04008825025596049,-0.14445310808685582,-0.5027007309924332,0.27049579609526114,0.001537164702395684,-0.14445310808685582,0.1673726504047501,0.33218262437609547,0.921762273203752,0.08458639893558295
2,945
Response to insulin
22
57
2.297743
0.021576
Q9HCD5,P31751,Q16836,Q15043,Q8WWQ0,Q6ZWJ1,P25054,Q08170,Q92922,P43490,Q9UQB8,O60763,P20020,P61026,Q13247,Q7L576,Q9H1E3,P42224,P61981,P22413,Q9BZF1,P62993
Processes and pathways
GO Biological process
msigdb_gobp
269,262,138,151,672,669,533,163,568,43,47,551,314,323,717,604,354,238,620,487,118,491
1662,1194,1047,1123,703,551,1470,2229,1342,2202,2055,1129,2172,1296,314,487,533,262,1808,238,1859,43,2100,1591,1539,2521,2377,1718,2721,323,620,491,1721,2459,163,2066,2139,717,151,1027,1028,138,1364,669,604,672,1500,568,2030,1370,887,118,354,269,1461,47,2159
-0.14445310808685582,0.06384901323418327,0.14670037120281113,0.10530734984835549,0.352714297145243,0.49601692885848886,-0.06092655176681376,-0.417912582552414,0.001537164702395684,-0.3967645192768137,-0.31236379292464844,0.10530734984835549,-0.37563575123099097,0.022324505727692668,0.8007319209650764,0.5572126623575777,0.5164299238420278,0.9016232814114782,-0.20728341801373437,0.9821019275934442,-0.22826282947820883,2.860424771989179,-0.33343552863307785,-0.10265492269446272,-0.08178207009671594,-0.6518579433658428,-0.5239474963343811,-0.16537868346442086,-0.9967910215997426,0.7805138743060999,0.4346904255440359,0.5572126623575777,-0.16537868346442086,-0.587809634186986,1.2422720024056197,-0.31236379292464844,-0.35452613486786577,0.352714297145243,1.2821160279306807,0.1673726504047501,0.1673726504047501,1.3815204900608,0.001537164702395684,0.3937322929558605,0.4551472654983724,0.3937322929558605,-0.06092655176681376,0.49601692885848886,-0.29131079005371857,0.001537164702395684,0.2499026019446144,1.5992054978277717,0.7400374285311478,0.9016232814114782,-0.04008825025596049,2.688128608527772,-0.35452613486786577
2,945
Switching of origins to a post replicative state
7
60
2.293419
0.021824
Q14566,P25787,P60900,P28072,Q13042,Q9Y619,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
227,3,196,69,179,50,31
550,2398,2163,1523,1337,1622,1672,261,795,422,1249,3,1533,2483,1631,31,69,829,1801,1251,1713,1352,2318,1809,2578,2505,469,981,561,1306,196,580,1863,1638,1595,2523,2244,179,1210,2216,1311,2020,227,2750,1265,1106,2279,504,1114,1695,1191,2082,1893,1234,2616,787,1237,1568,2480,50
0.49601692885848886,-0.5452144624387532,-0.37563575123099097,-0.08178207009671594,0.001537164702395684,-0.12354522852272666,-0.14445310808685582,0.9016232814114782,0.2910734677256283,0.6386074394794051,0.04309508514240472,6.86435802761024,-0.08178207009671594,-0.609138164405286,-0.12354522852272666,3.5053441140537633,2.2639439873853995,0.27049579609526114,-0.20728341801373437,0.04309508514240472,-0.16537868346442086,0.001537164702395684,-0.4814740099977851,-0.20728341801373437,-0.7160969742146781,-0.6304875446399937,0.5775825719273033,0.18802891238331532,0.49601692885848886,0.022324505727692668,1.1224519125778383,0.4755894045159319,-0.22826282947820883,-0.12354522852272666,-0.10265492269446272,-0.6518579433658428,-0.417912582552414,1.1824164060489466,0.06384901323418327,-0.3967645192768137,0.022324505727692668,-0.29131079005371857,1.0222645998514908,-1.0839642060391366,0.04309508514240472,0.12601197226717611,-0.4390800866390325,0.5572126623575777,0.12601197226717611,-0.14445310808685582,0.08458639893558295,-0.31236379292464844,-0.22826282947820883,0.06384901323418327,-0.7590312945413134,0.3116357123478239,0.06384901323418327,-0.08178207009671594,-0.587809634186986,2.592105567404909
2,945
Dyspnea
12
95
2.293335
0.021829
Q15165,P03886,P21281,P11310,Q8TCJ2,O75844,P00846,Q9Y619,P35637,Q969N2,O95831,Q6UN15
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
0,2,105,11,111,80,18,50,115,152,89,125
1946,2400,528,1049,373,2258,80,974,1164,1527,89,2719,18,739,790,2,2746,293,2767,763,2932,2482,1472,2720,359,2831,530,1851,11,2456,2234,390,2236,1168,1130,105,1346,2127,487,1477,2057,115,1536,1353,1752,1134,424,2503,1099,1137,711,2181,939,2269,2346,869,2438,833,1679,2377,2010,1207,2623,772,2018,2409,2929,873,718,1965,1314,1765,2638,0,2108,125,2762,111,1321,180,2188,152,1452,747,1152,2734,1563,1455,1459,2599,2933,700,1192,2480,50
-0.2702763842063141,-0.5452144624387532,0.5164299238420278,0.14670037120281113,0.6995066854647584,-0.4390800866390325,2.0501568052051606,0.18802891238331532,0.08458639893558295,-0.08178207009671594,1.9330438639514882,-0.9967910215997426,4.364245678303629,0.33218262437609547,0.2910734677256283,7.077162194942315,-1.0839642060391366,0.8411280257469278,-1.1277013965550577,0.3116357123478239,-3.890742390654541,-0.609138164405286,-0.06092655176681376,-0.9967910215997426,0.7197788815940095,-1.3923607141779688,0.5164299238420278,-0.22826282947820883,4.9168542761704375,-0.587809634186986,-0.417912582552414,0.6792207642978566,-0.417912582552414,0.08458639893558295,0.10530734984835549,1.7370381436593936,0.001537164702395684,-0.35452613486786577,0.5572126623575777,-0.06092655176681376,-0.31236379292464844,1.618928329270631,-0.08178207009671594,0.001537164702395684,-0.18632207833549766,0.10530734984835549,0.6386074394794051,-0.6304875446399937,0.12601197226717611,0.10530734984835549,0.352714297145243,-0.37563575123099097,0.20866925843125922,-0.4390800866390325,-0.5027007309924332,0.2499026019446144,-0.5665017880289501,0.27049579609526114,-0.14445310808685582,-0.5239474963343811,-0.29131079005371857,0.06384901323418327,-0.7805314905603624,0.3116357123478239,-0.29131079005371857,-0.5452144624387532,-3.571580495971794,0.2499026019446144,0.352714297145243,-0.2702763842063141,0.022324505727692668,-0.18632207833549766,-0.8020539598800626,7.623940234694683,-0.33343552863307785,1.5004260995112062,-1.105820052560868,1.6780316249499048,0.022324505727692668,1.1824164060489466,-0.37563575123099097,1.2821160279306807,-0.04008825025596049,0.33218262437609547,0.10530734984835549,-1.01854725430779,-0.08178207009671594,-0.04008825025596049,-0.04008825025596049,-0.7375531840373677,-4.163068613869287,0.37323082292864296,0.08458639893558295,-0.587809634186986,2.592105567404909
2,945
Xerostomia
6
14
2.293186
0.021837
Q15165,P55011,P09651,Q92804,P35637,Q14739
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
0,232,359,180,115,29
1164,2482,359,115,424,711,232,1679,2018,718,29,0,180,700
0.08458639893558295,-0.609138164405286,0.7197788815940095,1.618928329270631,0.6386074394794051,0.352714297145243,1.0021895959906988,-0.14445310808685582,-0.29131079005371857,0.352714297145243,3.655794126757704,7.623940234694683,1.1824164060489466,0.37323082292864296
2,945
Abc family proteins mediated transport
11
49
2.292222
0.021893
P25787,P60900,P28072,Q9BUN8,Q99436,Q9GZP9,P20618,P51665,O00231,P49721,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
3,196,69,38,504,369,261,561,550,469,31
550,2398,2163,1523,1337,1900,1622,1008,1012,1433,1672,1169,261,1249,3,1533,2483,1631,31,69,829,2558,2318,1714,1809,2578,2505,469,561,1306,1679,196,580,1863,1638,1595,2244,1210,2750,1265,1032,2279,504,1114,38,369,1189,1237,1568
0.49601692885848886,-0.5452144624387532,-0.37563575123099097,-0.08178207009671594,0.001537164702395684,-0.2492604414061187,-0.12354522852272666,0.1673726504047501,0.1673726504047501,-0.04008825025596049,-0.14445310808685582,0.08458639893558295,0.9016232814114782,0.04309508514240472,6.86435802761024,-0.08178207009671594,-0.609138164405286,-0.12354522852272666,3.5053441140537633,2.2639439873853995,0.27049579609526114,-0.6946624831235061,-0.4814740099977851,-0.16537868346442086,-0.20728341801373437,-0.7160969742146781,-0.6304875446399937,0.5775825719273033,0.49601692885848886,0.022324505727692668,-0.14445310808685582,1.1224519125778383,0.4755894045159319,-0.22826282947820883,-0.12354522852272666,-0.10265492269446272,-0.417912582552414,0.06384901323418327,-1.0839642060391366,0.04309508514240472,0.1673726504047501,-0.4390800866390325,0.5572126623575777,0.12601197226717611,3.1270939109566753,0.7197788815940095,0.08458639893558295,0.06384901323418327,-0.08178207009671594
2,945
Positive regulation of mrna splicing via spliceosome
6
16
2.280442
0.022582
P62995,P52948,P38159,Q96E39,P98179,Q14011
Processes and pathways
GO Biological process
msigdb_gobp
197,295,109,173,61,93
1092,1294,532,2373,109,295,197,61,872,946,346,93,173,1834,1238,733
0.12601197226717611,0.022324505727692668,0.5164299238420278,-0.5239474963343811,1.6780316249499048,0.8411280257469278,1.1224519125778383,2.399390495804993,0.2499026019446144,0.20866925843125922,0.7400374285311478,1.8939254041622147,1.202380291141655,-0.20728341801373437,0.06384901323418327,0.352714297145243
2,945
Translocase
9
24
2.27961
0.022631
P03886,P00403,P35670,Q13423,P23634,Q04656,P06576,Q9HD20,P20020
Functions
Protein Atlas Molecular function
protein_atlas_molecular_function
2,166,272,112,240,148,332,253,314
1577,373,705,166,2,1090,332,1433,1951,683,2204,314,240,2093,272,1018,2594,2376,2561,2776,148,112,1974,253
-0.10265492269446272,0.6995066854647584,0.352714297145243,1.2223321368163933,7.077162194942315,0.12601197226717611,0.7602824013383189,-0.04008825025596049,-0.2702763842063141,0.37323082292864296,-0.3967645192768137,0.8007319209650764,0.9620015287859891,-0.33343552863307785,0.8814712891547717,0.1673726504047501,-0.7375531840373677,-0.5239474963343811,-0.6946624831235061,-1.1496084842326584,1.3020203038267055,1.6583413438014383,-0.2702763842063141,0.9418883330481125
2,945
Cation transmembrane transporter activity
22
78
2.27906
0.022663
Q70HW3,Q9Y487,P35670,P00846,P08195,Q04656,Q15043,O43772,P00403,Q9Y619,Q93050,P20020,Q96QD8,P05026,Q96ES6,P06576,P55011,P21281,Q13423,P23634,Q9Y5K8,Q9HD20
Functions
GO Molecular function
msigdb_gomf
10,140,272,18,144,148,151,34,166,50,187,314,66,201,84,332,232,105,112,240,387,253
446,1663,34,2227,1385,2896,2865,166,18,1090,201,2747,332,1341,1052,144,1951,1015,2456,2815,683,2457,314,794,105,2174,240,2908,1435,1201,1802,272,1807,1252,1018,2594,2298,2437,232,2709,1815,2522,1024,2561,2623,2348,148,112,151,1318,2248,2701,10,1179,2655,2744,990,2308,842,187,1112,84,569,66,2841,384,1376,727,2684,253,2613,652,2829,2041,758,140,387,50
0.597938284242163,-0.14445310808685582,3.392192755458683,-0.417912582552414,-0.01926704960112091,-2.003165196484295,-1.661197007707223,1.2223321368163933,4.364245678303629,0.12601197226717611,1.1024392652871489,-1.0839642060391366,0.7602824013383189,0.001537164702395684,0.14670037120281113,1.321912831571934,-0.2702763842063141,0.1673726504047501,-0.587809634186986,-1.3037005802478918,0.37323082292864296,-0.587809634186986,0.8007319209650764,0.2910734677256283,1.7370381436593936,-0.37563575123099097,0.9620015287859891,-2.304369890271652,-0.04008825025596049,0.06384901323418327,-0.20728341801373437,0.8814712891547717,-0.20728341801373437,0.04309508514240472,0.1673726504047501,-0.7375531840373677,-0.4602671791946553,-0.5665017880289501,1.0021895959906988,-0.9533513246189271,-0.20728341801373437,-0.6518579433658428,0.1673726504047501,-0.6946624831235061,-0.7805314905603624,-0.5027007309924332,1.3020203038267055,1.6583413438014383,1.2821160279306807,0.022324505727692668,-0.417912582552414,-0.9316674210504035,5.045004847981975,0.08458639893558295,-0.845166484742484,-1.0621336151647116,0.18802891238331532,-0.4602671791946553,0.27049579609526114,1.142452277500605,0.12601197226717611,1.9916454712619938,0.49601692885848886,2.3607380919625607,-1.4814863787458754,0.6995066854647584,0.001537164702395684,0.352714297145243,-0.8883704331508439,0.9418883330481125,-0.7590312945413134,0.4142187974298949,-1.3701528148541127,-0.29131079005371857,0.33218262437609547,1.3616628687817531,0.6995066854647584,2.592105567404909
2,945
Rna stabilization
13
27
2.275039
0.022904
P11940,P67809,Q08J23,Q9H2U1,P98175,Q92804,Q13151,P35637,Q14103,O60506,Q9H814,Q14011,P07910
Processes and pathways
GO Biological process
msigdb_gobp
660,129,392,695,515,180,563,115,335,215,478,93,401
215,1995,1384,1527,401,660,115,980,129,515,1722,1492,392,2018,563,93,335,988,1027,1030,1878,180,812,695,478,1002,733
1.0423270044122548,-0.29131079005371857,-0.01926704960112091,-0.08178207009671594,0.6589210414523182,0.3937322929558605,1.618928329270631,0.18802891238331532,1.4410244250244986,0.5368284738518867,-0.16537868346442086,-0.06092655176681376,0.6792207642978566,-0.29131079005371857,0.49601692885848886,1.8939254041622147,0.7602824013383189,0.18802891238331532,0.1673726504047501,0.1673726504047501,-0.22826282947820883,1.1824164060489466,0.2910734677256283,0.37323082292864296,0.5775825719273033,0.18802891238331532,0.352714297145243
2,945
Abnormality of the coagulation cascade
6
37
2.273739
0.022982
Q9H845,Q16836,Q9Y487,Q9Y619,Q6NUQ1,Q6UN15
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
70,138,140,50,28,125
1193,1049,1161,763,530,2372,2620,1803,1673,1252,1353,1018,1019,1134,1808,231,939,2321,1026,2459,1443,1314,138,2248,2782,28,125,1828,1880,2074,70,2532,1119,1935,654,140,50
0.06384901323418327,0.14670037120281113,0.08458639893558295,0.3116357123478239,0.5164299238420278,-0.5239474963343811,-0.7805314905603624,-0.20728341801373437,-0.14445310808685582,0.04309508514240472,0.001537164702395684,0.1673726504047501,0.1673726504047501,0.10530734984835549,-0.20728341801373437,1.0021895959906988,0.20866925843125922,-0.4814740099977851,0.1673726504047501,-0.587809634186986,-0.04008825025596049,0.022324505727692668,1.3815204900608,-0.417912582552414,-1.1715415663081576,3.6745672923672013,1.5004260995112062,-0.20728341801373437,-0.22826282947820883,-0.31236379292464844,2.2057541946060866,-0.6518579433658428,0.12601197226717611,-0.2492604414061187,0.4142187974298949,1.3616628687817531,2.592105567404909
2,945
Transcriptional regulation by runx3
10
43
2.26825
0.023314
Q13951,P25787,P60900,P28072,Q99436,P20618,P51665,O00231,P49721,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
283,3,196,69,504,261,561,550,469,31
550,2398,2163,1523,1337,1622,1668,1672,261,1348,1249,3,1533,2483,1631,31,69,829,2001,2318,937,1809,2578,2505,469,561,1306,196,580,1863,1638,1595,2244,664,1210,946,283,1265,2279,504,1114,1237,1568
0.49601692885848886,-0.5452144624387532,-0.37563575123099097,-0.08178207009671594,0.001537164702395684,-0.12354522852272666,-0.14445310808685582,-0.14445310808685582,0.9016232814114782,0.001537164702395684,0.04309508514240472,6.86435802761024,-0.08178207009671594,-0.609138164405286,-0.12354522852272666,3.5053441140537633,2.2639439873853995,0.27049579609526114,-0.29131079005371857,-0.4814740099977851,0.20866925843125922,-0.20728341801373437,-0.7160969742146781,-0.6304875446399937,0.5775825719273033,0.49601692885848886,0.022324505727692668,1.1224519125778383,0.4755894045159319,-0.22826282947820883,-0.12354522852272666,-0.10265492269446272,-0.417912582552414,0.3937322929558605,0.06384901323418327,0.20866925843125922,0.8613062272321225,0.04309508514240472,-0.4390800866390325,0.5572126623575777,0.12601197226717611,0.06384901323418327,-0.08178207009671594
2,945
Hypopituitarism
6
30
2.262285
0.02368
Q969G3,Q12768,Q07864,Q9UMX1,Q4J6C6,Q03164
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
257,130,162,260,137,13
1991,1706,2401,1668,530,2001,2010,1594,13,162,130,1067,690,137,1828,1074,1182,2251,672,257,1773,1455,2361,850,1378,1703,758,260,289,1192
-0.29131079005371857,-0.16537868346442086,-0.5452144624387532,-0.14445310808685582,0.5164299238420278,-0.29131079005371857,-0.29131079005371857,-0.10265492269446272,4.659667932546476,1.2422720024056197,1.4410244250244986,0.14670037120281113,0.37323082292864296,1.4013665868313239,-0.20728341801373437,0.14670037120281113,0.08458639893558295,-0.417912582552414,0.3937322929558605,0.921762273203752,-0.18632207833549766,-0.04008825025596049,-0.5027007309924332,0.27049579609526114,0.001537164702395684,-0.14445310808685582,0.33218262437609547,0.921762273203752,0.8613062272321225,0.08458639893558295
2,945
Orc1 removal from chromatin
6
51
2.258765
0.023898
Q14566,P25787,P60900,P28072,Q9Y619,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
227,3,196,69,50,31
550,2398,2163,1523,1337,1622,1672,261,795,422,1249,3,1533,2483,1631,31,69,829,1251,1713,1352,2318,1809,2578,2505,469,981,561,1306,196,580,1863,1638,1595,2523,2244,1210,2216,1311,2020,227,2750,1265,2279,504,1114,1191,1237,1568,2480,50
0.49601692885848886,-0.5452144624387532,-0.37563575123099097,-0.08178207009671594,0.001537164702395684,-0.12354522852272666,-0.14445310808685582,0.9016232814114782,0.2910734677256283,0.6386074394794051,0.04309508514240472,6.86435802761024,-0.08178207009671594,-0.609138164405286,-0.12354522852272666,3.5053441140537633,2.2639439873853995,0.27049579609526114,0.04309508514240472,-0.16537868346442086,0.001537164702395684,-0.4814740099977851,-0.20728341801373437,-0.7160969742146781,-0.6304875446399937,0.5775825719273033,0.18802891238331532,0.49601692885848886,0.022324505727692668,1.1224519125778383,0.4755894045159319,-0.22826282947820883,-0.12354522852272666,-0.10265492269446272,-0.6518579433658428,-0.417912582552414,0.06384901323418327,-0.3967645192768137,0.022324505727692668,-0.29131079005371857,1.0222645998514908,-1.0839642060391366,0.04309508514240472,-0.4390800866390325,0.5572126623575777,0.12601197226717611,0.08458639893558295,0.06384901323418327,-0.08178207009671594,-0.587809634186986,2.592105567404909
2,945
Catalytic step 2 spliceosome
27
62
2.257451
0.02398
P31943,O75934,Q99459,P61978,O60306,P52272,P07910,O43390,Q12874,P51991,Q14562,Q9Y5S9,Q9UJV9,Q07955,O43290,Q9Y3C6,O60506,Q92620,P52597,P22626,Q9Y3B4,Q96DF8,P38159,P09651,Q13435,P41223,Q15459
Localization
GO Cellular component
msigdb_gocc
375,374,523,134,636,535,401,169,562,182,56,465,462,324,447,613,215,229,225,224,634,367,109,359,494,488,518
447,169,1005,636,215,1125,1050,374,1387,401,930,359,1167,660,933,224,375,109,2003,488,1020,182,535,225,134,1680,2793,1440,2663,1722,2642,324,562,494,2410,946,56,1765,1766,518,912,1873,1267,2693,229,783,367,2566,523,1608,2334,1986,2192,1331,462,1236,1238,1937,2697,634,613,465
0.597938284242163,1.202380291141655,0.1673726504047501,0.4142187974298949,1.0423270044122548,0.10530734984835549,0.14670037120281113,0.6995066854647584,-0.01926704960112091,0.6589210414523182,0.20866925843125922,0.7197788815940095,0.08458639893558295,0.3937322929558605,0.20866925843125922,1.0222645998514908,0.6995066854647584,1.6780316249499048,-0.29131079005371857,0.5572126623575777,0.1673726504047501,1.1624404216515005,0.5164299238420278,1.0222645998514908,1.4212012137589964,-0.14445310808685582,-1.2154867397644784,-0.04008825025596049,-0.8667569312531026,-0.16537868346442086,-0.8235988933073602,0.7805138743060999,0.49601692885848886,0.5572126623575777,-0.5452144624387532,0.20866925843125922,2.4573001148610345,-0.18632207833549766,-0.18632207833549766,0.5368284738518867,0.2292937886448734,-0.22826282947820883,0.04309508514240472,-0.9100071940702691,1.0222645998514908,0.3116357123478239,0.7197788815940095,-0.6946624831235061,0.5368284738518867,-0.10265492269446272,-0.4814740099977851,-0.2702763842063141,-0.37563575123099097,0.022324505727692668,0.597938284242163,0.06384901323418327,0.06384901323418327,-0.2492604414061187,-0.9100071940702691,0.4346904255440359,0.4551472654983724,0.597938284242163
2,945
Sterol metabolic process
7
36
2.24975
0.024465
Q8WTV0,Q15392,Q16850,P37268,Q9BQE5,P48449,Q14739
Processes and pathways
GO Biological process
msigdb_gobp
32,5,101,12,51,91,29
1336,825,1008,2719,2773,2746,1852,2235,402,2237,512,107,12,2939,1202,91,1137,1059,1485,2826,1359,2063,405,2524,1313,29,1867,2350,5,2653,2847,101,32,51,2628,435
0.001537164702395684,0.27049579609526114,0.1673726504047501,-0.9967910215997426,-1.1496084842326584,-1.0839642060391366,-0.22826282947820883,-0.417912582552414,0.6589210414523182,-0.417912582552414,0.5368284738518867,1.7173799770740772,4.770037134790452,-5.399061502057131,0.06384901323418327,1.9134897350999418,0.10530734984835549,0.14670037120281113,-0.06092655176681376,-1.3701528148541127,0.001537164702395684,-0.31236379292464844,0.6589210414523182,-0.6518579433658428,0.022324505727692668,3.655794126757704,-0.22826282947820883,-0.5027007309924332,5.735788324107087,-0.845166484742484,-1.5262302338877283,1.7763226939226555,3.5053441140537633,2.5151278038931033,-0.7805314905603624,0.6386074394794051
2,945
Tcf dependent signaling in response to wnt
8
62
2.246859
0.024649
P25787,P60900,P28072,P31751,P20618,O14641,Q13547,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
3,196,69,262,261,181,54,31
550,2398,2163,181,1523,1621,1337,1622,1532,1672,2371,261,533,1249,3,1533,2483,1631,31,69,829,617,294,262,2001,2318,1809,2578,1479,2505,469,1539,905,561,1306,196,580,1863,1638,1595,1488,1597,2104,1545,2244,1210,1310,54,947,948,2750,1265,2867,2110,2279,504,1114,1456,1003,1237,1568,2364
0.49601692885848886,-0.5452144624387532,-0.37563575123099097,1.1624404216515005,-0.08178207009671594,-0.12354522852272666,0.001537164702395684,-0.12354522852272666,-0.08178207009671594,-0.14445310808685582,-0.5239474963343811,0.9016232814114782,0.5164299238420278,0.04309508514240472,6.86435802761024,-0.08178207009671594,-0.609138164405286,-0.12354522852272666,3.5053441140537633,2.2639439873853995,0.27049579609526114,0.4346904255440359,0.8411280257469278,0.9016232814114782,-0.29131079005371857,-0.4814740099977851,-0.20728341801373437,-0.7160969742146781,-0.06092655176681376,-0.6304875446399937,0.5775825719273033,-0.08178207009671594,0.2292937886448734,0.49601692885848886,0.022324505727692668,1.1224519125778383,0.4755894045159319,-0.22826282947820883,-0.12354522852272666,-0.10265492269446272,-0.06092655176681376,-0.10265492269446272,-0.33343552863307785,-0.08178207009671594,-0.417912582552414,0.06384901323418327,0.022324505727692668,2.4765850676126675,0.20866925843125922,0.20866925843125922,-1.0839642060391366,0.04309508514240472,-1.6837963753761036,-0.33343552863307785,-0.4390800866390325,0.5572126623575777,0.12601197226717611,-0.04008825025596049,0.18802891238331532,0.06384901323418327,-0.08178207009671594,-0.5027007309924332
2,945
Abnormality of blood circulation
13
65
2.244998
0.024768
O00330,Q969G3,Q9UMX1,Q9H845,P49257,Q9Y487,O76024,O75844,Q04656,Q6UN15,Q9NZ08,P21912,Q14739
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
193,257,260,70,231,140,76,80,148,125,22,119,29
193,1125,80,76,739,790,2746,2830,1243,763,1014,530,390,2727,827,119,1391,1346,487,1628,1477,533,2431,1750,2057,1803,2001,1252,1955,1018,1134,2486,902,231,1716,1590,1058,1756,2438,769,2062,906,404,2017,405,148,664,29,1314,2643,125,2703,1183,646,1879,1322,257,70,22,270,2933,1935,260,1192,140
1.1224519125778383,0.10530734984835549,2.0501568052051606,2.0891147678360613,0.33218262437609547,0.2910734677256283,-1.0839642060391366,-1.3923607141779688,0.04309508514240472,0.3116357123478239,0.1673726504047501,0.5164299238420278,0.6792207642978566,-1.01854725430779,0.27049579609526114,1.5794717175274886,-0.01926704960112091,0.001537164702395684,0.5572126623575777,-0.12354522852272666,-0.06092655176681376,0.5164299238420278,-0.5665017880289501,-0.18632207833549766,-0.31236379292464844,-0.20728341801373437,-0.29131079005371857,0.04309508514240472,-0.2702763842063141,0.1673726504047501,0.10530734984835549,-0.609138164405286,0.2292937886448734,1.0021895959906988,-0.16537868346442086,-0.10265492269446272,0.14670037120281113,-0.18632207833549766,-0.5665017880289501,0.3116357123478239,-0.31236379292464844,0.2292937886448734,0.6589210414523182,-0.29131079005371857,0.6589210414523182,1.3020203038267055,0.3937322929558605,3.655794126757704,0.022324505727692668,-0.8235988933073602,1.5004260995112062,-0.9316674210504035,0.08458639893558295,0.4142187974298949,-0.22826282947820883,0.022324505727692668,0.921762273203752,2.2057541946060866,3.824492664661767,0.9016232814114782,-4.163068613869287,-0.2492604414061187,0.921762273203752,0.08458639893558295,1.3616628687817531
2,945
Hemiplegia hemiparesis
6
32
2.236284
0.025333
Q969G3,P03886,P00403,Q96T58,O60313,Q9NZ08
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
257,2,166,208,174,22
678,174,1996,2453,166,1746,739,2,1668,1346,487,1584,1673,1859,902,1716,2869,1756,1022,712,2062,664,2643,959,257,208,1187,2754,1777,22,260,1335
0.37323082292864296,1.1824164060489466,-0.29131079005371857,-0.587809634186986,1.2223321368163933,-0.18632207833549766,0.33218262437609547,7.077162194942315,-0.14445310808685582,0.001537164702395684,0.5572126623575777,-0.10265492269446272,-0.14445310808685582,-0.22826282947820883,0.2292937886448734,-0.16537868346442086,-1.7064250666788545,-0.18632207833549766,0.1673726504047501,0.352714297145243,-0.31236379292464844,0.3937322929558605,-0.8235988933073602,0.20866925843125922,0.921762273203752,1.0824142734467934,0.08458639893558295,-1.0839642060391366,-0.18632207833549766,3.824492664661767,0.921762273203752,0.022324505727692668
2,945
Mrna transport
22
71
2.235252
0.025401
Q9BTX1,Q08J23,Q86U42,Q16629,P52948,Q9ULX6,Q8NFH4,P51991,Q96PU8,Q8N1F7,Q5SRE5,Q07955,Q8TD16,Q96FV9,Q8TEM1,P22626,Q9NPA8,Q96MU7,Q8NFH5,P09651,O75694,Q06787
Processes and pathways
GO Biological process
msigdb_gobp
259,392,276,407,295,573,320,182,330,327,325,324,87,476,353,224,506,368,501,359,485,254
1380,1662,1046,1621,1160,485,359,578,224,1536,1478,1056,2101,1590,182,295,712,2488,1760,2137,713,871,254,324,1492,392,872,1913,2066,1263,407,2678,325,1071,1406,1407,840,276,1267,2703,327,1450,320,501,2251,87,353,959,1689,1269,1226,919,476,1412,368,330,1034,259,1609,1415,1561,2078,506,2361,1002,1891,1423,573,2046,2117,2160
-0.01926704960112091,-0.14445310808685582,0.14670037120281113,-0.12354522852272666,0.08458639893558295,0.5572126623575777,0.7197788815940095,0.4755894045159319,1.0222645998514908,-0.08178207009671594,-0.06092655176681376,0.14670037120281113,-0.33343552863307785,-0.10265492269446272,1.1624404216515005,0.8411280257469278,0.352714297145243,-0.609138164405286,-0.18632207833549766,-0.35452613486786577,0.352714297145243,0.2499026019446144,0.921762273203752,0.7805138743060999,-0.06092655176681376,0.6792207642978566,0.2499026019446144,-0.2492604414061187,-0.31236379292464844,0.04309508514240472,0.6589210414523182,-0.8883704331508439,0.7805138743060999,0.14670037120281113,-0.01926704960112091,-0.01926704960112091,0.27049579609526114,0.8814712891547717,0.04309508514240472,-0.9316674210504035,0.7805138743060999,-0.04008825025596049,0.8007319209650764,0.5572126623575777,-0.417912582552414,1.9525878342172756,0.7400374285311478,0.20866925843125922,-0.14445310808685582,0.04309508514240472,0.06384901323418327,0.2292937886448734,0.5775825719273033,-0.01926704960112091,0.7197788815940095,0.7805138743060999,0.1673726504047501,0.921762273203752,-0.10265492269446272,-0.01926704960112091,-0.08178207009671594,-0.31236379292464844,0.5572126623575777,-0.5027007309924332,0.18802891238331532,-0.22826282947820883,-0.01926704960112091,0.49601692885848886,-0.29131079005371857,-0.33343552863307785,-0.35452613486786577
2,945
Degradation of beta catenin by the destruction complex
12
50
2.228476
0.025849
P25787,P60900,P28072,Q99436,P30154,P25054,P20618,P51665,O00231,Q13547,P49721,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
3,196,69,504,294,533,261,561,550,54,469,31
550,2398,2163,1523,1337,1622,1672,261,533,1249,3,1533,2483,1631,31,69,829,617,294,2001,2318,1809,2578,1479,2505,469,1539,561,1306,870,196,580,1863,1638,1595,2523,1545,2244,1210,1310,54,2020,948,2750,1265,2279,504,1114,1237,1568
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2,945
Metabolism of lipids
17
164
2.228267
0.025863
Q15165,O43772,Q15392,Q9BY49,Q8NCC3,Q96G23,Q16850,Q9NQZ5,P11310,P37268,Q8N8N7,P35610,Q9UBF8,Q9NPH0,Q9BZF1,P48449,Q14739
Processes and pathways
Reactome Pathways
msigdb_reactome
0,34,5,37,7,72,101,42,11,12,75,107,16,17,118,91,29
300,309,2397,2892,819,279,1788,1286,1159,34,2227,2313,1708,1709,2687,2051,825,1164,899,1580,2786,1848,738,1905,2773,2746,2830,1243,2767,2872,2932,2844,2601,1850,2708,11,2235,2126,2910,1168,2889,2927,2371,486,1999,1346,1347,1016,2237,1477,2519,2206,1132,2868,2095,512,107,1673,12,1808,1586,1860,1202,557,2749,91,2436,1634,980,1716,1137,2869,2917,868,1593,2346,1059,769,1485,1960,1258,1961,403,1596,2104,2063,2722,405,1963,2859,1144,2929,2897,2524,1313,29,1867,2873,1211,602,2350,0,2107,5,1148,1966,2653,2847,138,101,538,1728,2723,779,1496,211,1031,1320,2679,804,443,75,337,475,958,7,1646,1830,2145,1604,1411,72,394,810,675,1982,2894,1839,2446,213,37,118,2696,813,2473,17,1699,42,1932,2836,1082,1280,2599,1890,16,2628,1158,729,2154,2363,733,2158,1519,1520
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2,945
Muscle cell differentiation
13
59
2.21475
0.026777
Q96PU8,P67809,Q92990,Q9P2K5,P11310,Q9BWF3,Q9H7B4,O75844,O75179,Q13547,Q7Z4V5,Q96TA1,Q9BYT8
Processes and pathways
GO Biological process
msigdb_gobp
330,129,328,199,11,239,14,80,331,54,183,88,383
680,448,2650,1847,331,80,972,1007,790,2690,1091,929,1292,530,11,1852,792,683,1343,1854,2484,1392,707,2001,742,1859,1675,1591,982,2299,129,1722,664,986,54,393,1965,2884,2638,1027,1727,1407,183,2679,1975,328,2356,330,88,887,239,383,1278,14,1190,199,2874,1938,1044
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2,945
Overlap between signal transduction pathways contributing to lmna laminopathies
7
15
2.210701
0.027057
O60725,P55209,O75844,Q9UPY3,P50402,Q13547,P25054
Processes and pathways
WikiPathways
msigdb_wp
6,265,80,548,315,54,533
6,80,790,2202,533,2001,797,556,1479,1539,315,265,54,548,732
5.699629863835562,2.0501568052051606,0.2910734677256283,-0.3967645192768137,0.5164299238420278,-0.29131079005371857,0.2910734677256283,0.49601692885848886,-0.06092655176681376,-0.08178207009671594,0.8007319209650764,0.9016232814114782,2.4765850676126675,0.5164299238420278,0.352714297145243
2,945
Response to endogenous stimulus
40
264
2.20613
0.027375
Q15392,Q9HCD5,Q16836,P31751,Q9H7B4,Q04656,Q15043,P62942,Q9Y4E8,P42785,O95429,Q08170,P35613,P43490,Q5JRA6,Q9UQ13,Q9NS86,Q9UQB8,P19174,Q13547,Q96PK6,Q02790,P20020,O00330,P61026,P08670,Q9H270,O75844,Q99729,Q14103,O95831,Q05397,Q9H1E3,Q8IZL8,P35610,P42224,O15173,P23634,Q9BZF1,Q8N0X7
Processes and pathways
GO Biological process
msigdb_gobp
5,269,138,262,14,148,151,25,290,27,156,163,161,43,172,308,305,47,53,54,188,58,314,193,323,205,339,80,209,335,89,217,354,352,107,238,237,240,118,251
2288,1662,1194,193,446,592,820,1047,1744,1787,2851,1336,237,1123,2121,1794,2650,703,1994,551,400,484,1901,2427,80,595,552,1007,859,1579,156,89,2746,862,1668,2631,1090,1091,2600,1669,1470,2229,2670,1197,1951,205,1472,2259,1342,1850,1093,2538,1294,2202,1295,578,2055,468,1129,2125,1094,437,2889,402,2172,1343,933,1296,53,532,314,2846,2372,487,1628,240,2519,533,1435,2484,1097,2177,2557,707,2820,2094,2868,262,2095,2096,1352,708,866,2001,977,618,1133,107,161,2003,1134,1808,936,238,1859,1675,27,43,2099,2520,1715,558,1136,2749,2100,2504,1138,1591,1539,1058,2521,1717,905,1485,2377,1718,2721,323,1258,2183,2011,2135,581,620,1596,1639,25,491,2104,1598,1721,2348,1819,1722,58,148,1491,2607,217,345,2459,664,163,1723,2066,2859,1549,516,987,2139,717,2216,1763,1262,1147,54,946,335,2245,1821,2349,1866,1067,1314,151,2107,2867,5,1726,1966,1362,2326,1918,666,1027,1028,138,1727,172,2141,1364,1030,669,604,1320,1368,352,251,2386,2511,806,671,672,2029,1500,1688,2467,918,2529,568,2030,1606,2188,994,1370,1503,540,1372,1559,674,188,784,2753,2682,887,2332,209,1982,2796,118,889,2150,650,354,339,1510,1278,965,14,2447,269,2151,1701,305,2613,1461,1421,1119,1003,1040,1424,1936,547,1782,308,47,731,893,732,2496,2200,290,2903,2159
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2,945
Predicted secreted proteins
9
48
2.200686
0.027758
Q15165,O94919,Q9UMX5,P80303,P43490,Q07021,Q9NZ08,O60888,Q8WUJ1
Functions
Protein Atlas Protein class
protein_atlas_protein_class
0,99,103,40,43,178,22,23,57
23,388,552,99,2481,862,1669,1341,1128,2575,1851,2913,1129,487,2592,1097,43,767,2438,2826,40,2891,177,1820,178,2461,1723,1641,2215,0,2788,2508,2768,57,1923,1733,1502,1884,2310,2472,2853,1738,2754,2725,22,103,2885,2647
3.8057770547646164,0.6792207642978566,0.49601692885848886,1.7959491708481627,-0.609138164405286,0.2499026019446144,-0.14445310808685582,0.001537164702395684,0.10530734984835549,-0.7160969742146781,-0.22826282947820883,-2.586040646525843,0.10530734984835549,0.5572126623575777,-0.7375531840373677,0.12601197226717611,2.860424771989179,0.3116357123478239,-0.5665017880289501,-1.3701528148541127,2.91770423556765,-1.9572118375424268,1.1824164060489466,-0.20728341801373437,1.1824164060489466,-0.587809634186986,-0.16537868346442086,-0.12354522852272666,-0.3967645192768137,7.623940234694683,-1.1935008981215134,-0.6304875446399937,-1.1277013965550577,2.4573001148610345,-0.2492604414061187,-0.16537868346442086,-0.06092655176681376,-0.22826282947820883,-0.4602671791946553,-0.587809634186986,-1.5710975994835399,-0.16537868346442086,-1.0839642060391366,-0.9967910215997426,3.824492664661767,1.7763226939226555,-1.888482982023875,-0.8235988933073602
2,945
Proportionate short stature
6
32
2.200192
0.027793
Q07864,Q15392,Q16836,Q9Y619,P21912,Q14739
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
162,5,138,50,119,29
2401,2258,2708,530,2889,1054,119,2176,2129,1750,2058,2001,2266,1808,2436,2672,833,1910,162,473,29,5,690,138,2275,172,1690,1372,1836,1459,2480,50
-0.5452144624387532,-0.4390800866390325,-0.9533513246189271,0.5164299238420278,-1.9342751994429657,0.14670037120281113,1.5794717175274886,-0.37563575123099097,-0.35452613486786577,-0.18632207833549766,-0.31236379292464844,-0.29131079005371857,-0.4390800866390325,-0.20728341801373437,-0.5665017880289501,-0.8883704331508439,0.27049579609526114,-0.2492604414061187,1.2422720024056197,0.5775825719273033,3.655794126757704,5.735788324107087,0.37323082292864296,1.3815204900608,-0.4390800866390325,1.202380291141655,-0.14445310808685582,0.001537164702395684,-0.20728341801373437,-0.04008825025596049,-0.587809634186986,2.592105567404909
2,945
Nuclear envelope ne reassembly
23
49
2.195672
0.028115
Q9BTX1,P53990,Q9BUF5,Q14739,P20700,P02545,P52948,P04350,Q9UQN3,P42166,Q86XL3,P63151,P50402,Q7Z3B4,Q8NFH4,P42167,Q8N1F7,Q5SRE5,Q9Y2U8,P57740,Q8NFH5,O75694,P30153
Processes and pathways
Reactome Pathways
msigdb_reactome
259,768,811,29,662,790,295,293,700,797,46,800,315,840,320,556,327,325,732,712,501,485,617
822,2201,485,790,293,929,1434,2261,662,617,1478,797,556,2099,315,295,768,712,1596,800,1913,1146,29,1211,325,840,46,2704,1368,327,2511,1450,320,501,959,2187,1689,1833,919,1693,259,811,1187,1609,1415,1567,700,732,1121
0.27049579609526114,-0.3967645192768137,0.5572126623575777,0.2910734677256283,0.8411280257469278,0.20866925843125922,-0.04008825025596049,-0.4390800866390325,0.3937322929558605,0.4346904255440359,-0.06092655176681376,0.2910734677256283,0.49601692885848886,-0.33343552863307785,0.8007319209650764,0.8411280257469278,0.3116357123478239,0.352714297145243,-0.10265492269446272,0.2910734677256283,-0.2492604414061187,0.10530734984835549,3.655794126757704,0.06384901323418327,0.7805138743060999,0.27049579609526114,2.841314827134973,-0.9316674210504035,0.001537164702395684,0.7805138743060999,-0.6304875446399937,-0.04008825025596049,0.8007319209650764,0.5572126623575777,0.20866925843125922,-0.37563575123099097,-0.14445310808685582,-0.20728341801373437,0.2292937886448734,-0.14445310808685582,0.921762273203752,0.2910734677256283,0.08458639893558295,-0.10265492269446272,-0.01926704960112091,-0.08178207009671594,0.37323082292864296,0.352714297145243,0.12601197226717611
2,945
Talipes equinovarus
18
66
2.19342
0.028277
Q9Y5S9,Q15392,P61978,Q9Y487,Q6NUQ1,Q9HD42,Q9Y619,Q5H8A4,Q96AY3,Q9ULC3,Q9H2M9,Q8TD16,Q8TAA9,Q01082,Q9NWM8,Q02809,P16435,P49902
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
465,5,134,140,28,385,50,275,19,445,246,87,221,440,59,404,402,282
2785,2400,2401,825,1196,2865,1165,2906,1245,616,1748,1851,402,2429,2372,1391,2094,1252,1018,2003,1860,282,1593,769,1910,134,515,440,404,451,1065,1310,2897,2610,5,1553,275,28,1971,1974,2666,2795,647,221,1223,87,1369,2680,1879,1452,1228,19,246,2532,2684,385,59,787,445,758,1241,140,2480,465,2451,50
-1.1935008981215134,-0.5452144624387532,-0.5452144624387532,0.27049579609526114,0.06384901323418327,-1.661197007707223,0.08458639893558295,-2.23448571265435,0.04309508514240472,0.4346904255440359,-0.18632207833549766,-0.22826282947820883,0.6589210414523182,-0.5665017880289501,-0.5239474963343811,-0.01926704960112091,-0.33343552863307785,0.04309508514240472,0.1673726504047501,-0.29131079005371857,-0.22826282947820883,0.8613062272321225,-0.10265492269446272,0.3116357123478239,-0.2492604414061187,1.4212012137589964,0.5368284738518867,0.6182798801100748,0.6589210414523182,0.597938284242163,0.14670037120281113,0.022324505727692668,-2.003165196484295,-0.7590312945413134,5.735788324107087,-0.08178207009671594,0.8814712891547717,3.6745672923672013,-0.2702763842063141,-0.2702763842063141,-0.8667569312531026,-1.2154867397644784,0.4142187974298949,1.0423270044122548,0.06384901323418327,1.9525878342172756,0.001537164702395684,-0.8883704331508439,-0.22826282947820883,-0.04008825025596049,0.06384901323418327,4.34572728753516,0.9620015287859891,-0.6518579433658428,-0.8883704331508439,0.6995066854647584,2.438006058944413,0.3116357123478239,0.6182798801100748,0.33218262437609547,0.06384901323418327,1.3616628687817531,-0.587809634186986,0.597938284242163,-0.5665017880289501,2.592105567404909
2,945
Glucose intolerance
19
96
2.190423
0.028494
P03886,Q9UMX1,P31751,P00846,P00403,Q5JRA6,O60313,O96000,O00330,O76024,O75844,P61457,Q8TAA9,Q92620,P42224,Q96CU9,Q13217,Q06787,Q15056
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
2,260,262,18,166,172,174,63,193,76,80,86,221,229,238,113,241,254,255
2288,1991,193,678,1706,576,2648,2918,702,1468,174,1995,1577,373,2089,705,1050,2688,1996,80,76,1387,1527,63,166,18,790,2,1668,763,1624,530,2456,684,1296,2204,487,2093,1200,2129,262,2001,641,1806,1134,1908,238,937,557,560,2376,2580,1482,1022,2010,86,1864,1143,452,254,1443,241,255,172,1873,1828,2546,2794,2936,2509,1183,221,432,2564,229,113,1504,1836,1512,2115,2755,1459,1779,1082,1118,1617,260,1424,732,2083,1192,1241,2647,2863,2160,299
-0.4602671791946553,-0.29131079005371857,1.1224519125778383,0.37323082292864296,-0.16537868346442086,0.4755894045159319,-0.845166484742484,-2.894826421250636,0.352714297145243,-0.06092655176681376,1.1824164060489466,-0.29131079005371857,-0.10265492269446272,0.6995066854647584,-0.33343552863307785,0.352714297145243,0.14670037120281113,-0.9100071940702691,-0.29131079005371857,2.0501568052051606,2.0891147678360613,-0.01926704960112091,-0.08178207009671594,2.3800689170256426,1.2223321368163933,4.364245678303629,0.2910734677256283,7.077162194942315,-0.14445310808685582,0.3116357123478239,-0.12354522852272666,0.5164299238420278,-0.587809634186986,0.37323082292864296,0.022324505727692668,-0.3967645192768137,0.5572126623575777,-0.33343552863307785,0.06384901323418327,-0.35452613486786577,0.9016232814114782,-0.29131079005371857,0.4142187974298949,-0.20728341801373437,0.10530734984835549,-0.2492604414061187,0.9821019275934442,0.20866925843125922,0.49601692885848886,0.49601692885848886,-0.5239474963343811,-0.7160969742146781,-0.06092655176681376,0.1673726504047501,-0.29131079005371857,1.9525878342172756,-0.22826282947820883,0.10530734984835549,0.597938284242163,0.921762273203752,-0.04008825025596049,0.9620015287859891,0.921762273203752,1.202380291141655,-0.22826282947820883,-0.20728341801373437,-0.6732495316326513,-1.2154867397644784,-4.537593048427522,-0.6304875446399937,0.08458639893558295,1.0423270044122548,0.6386074394794051,-0.6946624831235061,1.0222645998514908,1.6386402615157454,-0.06092655176681376,-0.20728341801373437,-0.06092655176681376,-0.33343552863307785,-1.0839642060391366,-0.04008825025596049,-0.18632207833549766,0.14670037120281113,0.12601197226717611,-0.10265492269446272,0.921762273203752,-0.01926704960112091,0.352714297145243,-0.31236379292464844,0.08458639893558295,0.06384901323418327,-0.8235988933073602,-1.6386272017792467,-0.35452613486786577,0.8411280257469278
2,945
Organic hydroxy compound biosynthetic process
8
50
2.186334
0.028791
P00374,P05091,Q15392,Q16850,P37268,P61457,P48449,Q14739
Processes and pathways
GO Biological process
msigdb_gobp
1,67,5,101,12,86,91,29
2659,1845,279,2851,1788,1286,825,1008,1,2719,2773,2746,67,2556,1852,2235,402,2172,1347,1016,2558,271,12,1202,91,1059,1485,86,2063,405,148,2929,2524,1313,29,2350,5,2653,2847,1028,101,784,810,2682,2074,2696,2685,2628,2903,2451
-0.8667569312531026,-0.22826282947820883,0.8613062272321225,-1.5710975994835399,-0.20728341801373437,0.022324505727692668,0.27049579609526114,0.1673726504047501,7.448017023011698,-0.9967910215997426,-1.1496084842326584,-1.0839642060391366,2.341397984173776,-0.6946624831235061,-0.22826282947820883,-0.417912582552414,0.6589210414523182,-0.37563575123099097,0.001537164702395684,0.1673726504047501,-0.6946624831235061,0.8814712891547717,4.770037134790452,0.06384901323418327,1.9134897350999418,0.14670037120281113,-0.06092655176681376,1.9525878342172756,-0.31236379292464844,0.6589210414523182,1.3020203038267055,-3.571580495971794,-0.6518579433658428,0.022324505727692668,3.655794126757704,-0.5027007309924332,5.735788324107087,-0.845166484742484,-1.5262302338877283,0.1673726504047501,1.7763226939226555,0.3116357123478239,0.2910734677256283,-0.8883704331508439,-0.31236379292464844,-0.9100071940702691,-0.8883704331508439,-0.7805314905603624,-2.1185069787704807,-0.5665017880289501
2,945
Histone h3 acetylation
6
10
2.18316
0.029024
O95696,Q14012,Q03164,Q9NRF9,O95251,Q9Y6J9
Processes and pathways
GO Biological process
msigdb_gobp
194,393,13,247,155,466
155,194,2013,13,393,994,506,247,1613,466
1.262199946694982,1.1224519125778383,-0.29131079005371857,4.659667932546476,0.6792207642978566,0.18802891238331532,0.5572126623575777,0.9620015287859891,-0.10265492269446272,0.597938284242163
2,945
Organic hydroxy compound metabolic process
15
105
2.182281
0.029089
Q8WTV0,P00374,P05091,Q15392,Q9BY49,Q16850,P35610,P37268,P48735,O94788,Q9BQE5,P61457,P30837,P48449,Q14739
Processes and pathways
GO Biological process
msigdb_gobp
32,1,67,5,37,101,107,12,145,49,51,86,55,91,29
2659,1845,279,2851,1336,1788,1286,2553,1468,1049,824,825,595,49,1008,2799,2574,1,2719,1746,2773,2746,1668,67,2342,2601,2556,1852,2576,2235,2203,2126,402,2727,2172,1391,1347,1016,2237,2558,55,512,271,107,12,2939,1202,557,91,145,1137,2580,2008,982,868,1059,1485,2299,2801,86,2826,1359,1819,2063,2722,405,148,1963,2929,2019,2897,2524,1313,29,1867,2873,2350,5,1966,2653,2847,1028,101,1072,337,2819,2466,32,784,810,2682,2074,2778,51,846,37,2696,2685,2151,2628,435,342,2854,2903,2451
-0.8667569312531026,-0.22826282947820883,0.8613062272321225,-1.5710975994835399,0.001537164702395684,-0.20728341801373437,0.022324505727692668,-0.6946624831235061,-0.06092655176681376,0.14670037120281113,0.27049579609526114,0.27049579609526114,0.4551472654983724,2.6113277676568396,0.1673726504047501,-1.2374993562115237,-0.7160969742146781,7.448017023011698,-0.9967910215997426,-0.18632207833549766,-1.1496084842326584,-1.0839642060391366,-0.14445310808685582,2.341397984173776,-0.5027007309924332,-0.7590312945413134,-0.6946624831235061,-0.22826282947820883,-0.7160969742146781,-0.417912582552414,-0.3967645192768137,-0.35452613486786577,0.6589210414523182,-1.01854725430779,-0.37563575123099097,-0.01926704960112091,0.001537164702395684,0.1673726504047501,-0.417912582552414,-0.6946624831235061,2.4573001148610345,0.5368284738518867,0.8814712891547717,1.7173799770740772,4.770037134790452,-5.399061502057131,0.06384901323418327,0.49601692885848886,1.9134897350999418,1.321912831571934,0.10530734984835549,-0.7160969742146781,-0.29131079005371857,0.18802891238331532,0.2499026019446144,0.14670037120281113,-0.06092655176681376,-0.4602671791946553,-1.2374993562115237,1.9525878342172756,-1.3701528148541127,0.001537164702395684,-0.20728341801373437,-0.31236379292464844,-0.9967910215997426,0.6589210414523182,1.3020203038267055,-0.2702763842063141,-3.571580495971794,-0.29131079005371857,-2.003165196484295,-0.6518579433658428,0.022324505727692668,3.655794126757704,-0.22826282947820883,-1.751769488181549,-0.5027007309924332,5.735788324107087,-0.2702763842063141,-0.845166484742484,-1.5262302338877283,0.1673726504047501,1.7763226939226555,0.14670037120281113,0.7602824013383189,-1.3258230481672575,-0.587809634186986,3.5053441140537633,0.3116357123478239,0.2910734677256283,-0.8883704331508439,-0.31236379292464844,-1.1496084842326584,2.5151278038931033,0.27049579609526114,3.2408955872793364,-0.9100071940702691,-0.8883704331508439,-0.35452613486786577,-0.7805314905603624,0.6386074394794051,0.7602824013383189,-1.5710975994835399,-2.1185069787704807,-0.5665017880289501
2,945
Hepatic failure
7
46
2.181931
0.029115
P03886,O43772,O15460,Q9H845,Q9Y619,P00846,Q6NUQ1
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
2,34,100,70,50,18,28
1193,1336,100,34,1995,2630,825,1527,18,739,2,2746,763,1014,1951,826,2727,420,1477,2558,1803,272,2939,1714,1808,1908,2869,1960,2321,1963,1443,2929,1028,138,28,691,785,70,2532,2115,1779,1119,892,1516,482,50
0.06384901323418327,0.001537164702395684,1.7763226939226555,3.392192755458683,-0.29131079005371857,-0.8020539598800626,0.27049579609526114,-0.08178207009671594,4.364245678303629,0.33218262437609547,7.077162194942315,-1.0839642060391366,0.3116357123478239,0.1673726504047501,-0.2702763842063141,0.27049579609526114,-1.01854725430779,0.6386074394794051,-0.06092655176681376,-0.6946624831235061,-0.20728341801373437,0.8814712891547717,-5.399061502057131,-0.16537868346442086,-0.20728341801373437,-0.2492604414061187,-1.7064250666788545,-0.2702763842063141,-0.4814740099977851,-0.2702763842063141,-0.04008825025596049,-3.571580495971794,0.1673726504047501,1.3815204900608,3.6745672923672013,0.37323082292864296,0.3116357123478239,2.2057541946060866,-0.6518579433658428,-0.33343552863307785,-0.18632207833549766,0.12601197226717611,0.2499026019446144,-0.06092655176681376,0.5775825719273033,2.592105567404909
2,945
EF-hand domain pair [IPR011992]
12
50
2.175566
0.029588
Q96D71,Q9Y680,P80303,Q15293,P14314,O43852,Q96AY3,Q8N163,Q9H8M7,P19174,Q14257,Q9NWM8
Sequence
InterPro Superfamily
interpro_homologous_superfamily
258,98,40,139,390,48,19,277,412,53,26,59
680,48,1124,824,2865,1667,1166,2538,792,2603,390,2787,1343,53,1628,2056,831,557,559,2211,770,40,1820,451,1723,406,26,1602,139,1069,2276,2250,2352,2028,2385,277,2145,19,258,1884,2189,1842,1278,412,59,2902,1935,2155,730,98
0.37323082292864296,2.6113277676568396,0.10530734984835549,0.27049579609526114,-1.661197007707223,-0.14445310808685582,0.08458639893558295,-0.6732495316326513,0.2910734677256283,-0.7590312945413134,0.6792207642978566,-1.1935008981215134,0.001537164702395684,2.4765850676126675,-0.12354522852272666,-0.31236379292464844,0.27049579609526114,0.49601692885848886,0.49601692885848886,-0.3967645192768137,0.3116357123478239,2.91770423556765,-0.20728341801373437,0.597938284242163,-0.16537868346442086,0.6589210414523182,3.693333183718309,-0.10265492269446272,1.3616628687817531,0.14670037120281113,-0.4390800866390325,-0.417912582552414,-0.5027007309924332,-0.29131079005371857,-0.5239474963343811,0.8814712891547717,-0.35452613486786577,4.34572728753516,0.921762273203752,-0.22826282947820883,-0.37563575123099097,-0.20728341801373437,0.04309508514240472,0.6589210414523182,2.438006058944413,-2.0722926032580373,-0.2492604414061187,-0.35452613486786577,0.352714297145243,1.835170758534991
2,945
Mitotic g2 g2 m phases
21
82
2.175367
0.029603
P25787,P20618,P62140,O95684,O75935,P28070,P30154,P04350,P51665,O00231,P60900,P28072,Q9H6D7,P61289,Q99640,P49721,P61163,Q99436,P61981,P30153,Q15154
Processes and pathways
Reactome Pathways
msigdb_reactome
3,261,403,24,154,31,294,293,561,550,196,69,203,580,607,469,599,504,620,617,379
550,2398,2163,1523,1621,1337,895,858,1622,154,1431,24,293,1668,929,1246,900,1197,1434,1672,261,1248,2430,795,1249,3,1533,2483,1631,31,69,829,617,294,2318,1301,1809,2578,2505,469,561,2182,1306,196,2721,599,580,620,403,1863,1638,983,1595,800,2523,2244,1210,2105,1146,836,2020,1642,718,2563,2750,1265,379,1149,1070,913,2279,504,1114,607,648,811,1187,203,1237,1566,1568,2515
0.49601692885848886,-0.5452144624387532,-0.37563575123099097,-0.08178207009671594,-0.12354522852272666,0.001537164702395684,0.2292937886448734,0.2499026019446144,-0.12354522852272666,1.262199946694982,-0.04008825025596049,3.768324465880385,0.8411280257469278,-0.14445310808685582,0.20866925843125922,0.04309508514240472,0.2292937886448734,0.06384901323418327,-0.04008825025596049,-0.14445310808685582,0.9016232814114782,0.04309508514240472,-0.5665017880289501,0.2910734677256283,0.04309508514240472,6.86435802761024,-0.08178207009671594,-0.609138164405286,-0.12354522852272666,3.5053441140537633,2.2639439873853995,0.27049579609526114,0.4346904255440359,0.8411280257469278,-0.4814740099977851,0.022324505727692668,-0.20728341801373437,-0.7160969742146781,-0.6304875446399937,0.5775825719273033,0.49601692885848886,-0.37563575123099097,0.022324505727692668,1.1224519125778383,-0.9967910215997426,0.4551472654983724,0.4755894045159319,0.4346904255440359,0.6589210414523182,-0.22826282947820883,-0.12354522852272666,0.18802891238331532,-0.10265492269446272,0.2910734677256283,-0.6518579433658428,-0.417912582552414,0.06384901323418327,-0.33343552863307785,0.10530734984835549,0.27049579609526114,-0.29131079005371857,-0.12354522852272666,0.352714297145243,-0.6946624831235061,-1.0839642060391366,0.04309508514240472,0.6995066854647584,0.10530734984835549,0.14670037120281113,0.2292937886448734,-0.4390800866390325,0.5572126623575777,0.12601197226717611,0.4551472654983724,0.4142187974298949,0.2910734677256283,0.08458639893558295,1.1024392652871489,0.06384901323418327,-0.08178207009671594,-0.08178207009671594,-0.6304875446399937
2,945
Cellular response to peptide hormone stimulus
21
58
2.174094
0.029698
Q9HCD5,P31751,Q15043,Q8WWQ0,P16435,O75116,P25054,Q92922,P43490,Q9UQB8,O60763,P20020,P61026,Q05397,Q7L576,Q9H1E3,P42224,P61981,P22413,Q9BZF1,P62993
Processes and pathways
GO Biological process
msigdb_gobp
269,262,151,672,402,400,533,568,43,47,551,314,323,217,604,354,238,620,487,118,491
1662,1047,1123,1794,703,551,400,1470,2229,1342,2202,2055,1129,402,2172,1296,314,487,533,2557,262,1134,936,238,43,2099,1715,2100,1591,1539,2521,2377,2721,323,620,491,1721,217,2459,2066,2139,1262,151,1028,1364,669,604,672,1500,568,2030,1370,118,354,269,1461,47,2159
-0.14445310808685582,0.14670037120281113,0.10530734984835549,-0.20728341801373437,0.352714297145243,0.49601692885848886,0.6589210414523182,-0.06092655176681376,-0.417912582552414,0.001537164702395684,-0.3967645192768137,-0.31236379292464844,0.10530734984835549,0.6589210414523182,-0.37563575123099097,0.022324505727692668,0.8007319209650764,0.5572126623575777,0.5164299238420278,-0.6946624831235061,0.9016232814114782,0.10530734984835549,0.20866925843125922,0.9821019275934442,2.860424771989179,-0.33343552863307785,-0.16537868346442086,-0.33343552863307785,-0.10265492269446272,-0.08178207009671594,-0.6518579433658428,-0.5239474963343811,-0.9967910215997426,0.7805138743060999,0.4346904255440359,0.5572126623575777,-0.16537868346442086,1.0423270044122548,-0.587809634186986,-0.31236379292464844,-0.35452613486786577,0.04309508514240472,1.2821160279306807,0.1673726504047501,0.001537164702395684,0.3937322929558605,0.4551472654983724,0.3937322929558605,-0.06092655176681376,0.49601692885848886,-0.29131079005371857,0.001537164702395684,1.5992054978277717,0.7400374285311478,0.9016232814114782,-0.04008825025596049,2.688128608527772,-0.35452613486786577
2,945
Regulation of runx2 expression and activity
6
44
2.160682
0.03072
P25787,P60900,P28072,P20618,P42224,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
3,196,69,261,238,31
550,2398,2163,1523,1337,1622,1672,261,1249,3,1533,2483,1631,31,69,829,2318,238,1809,2578,2505,469,1539,561,1306,196,580,1863,1638,1595,2523,2244,1210,2216,2020,283,2750,1265,2279,504,1114,1237,1424,1568
0.49601692885848886,-0.5452144624387532,-0.37563575123099097,-0.08178207009671594,0.001537164702395684,-0.12354522852272666,-0.14445310808685582,0.9016232814114782,0.04309508514240472,6.86435802761024,-0.08178207009671594,-0.609138164405286,-0.12354522852272666,3.5053441140537633,2.2639439873853995,0.27049579609526114,-0.4814740099977851,0.9821019275934442,-0.20728341801373437,-0.7160969742146781,-0.6304875446399937,0.5775825719273033,-0.08178207009671594,0.49601692885848886,0.022324505727692668,1.1224519125778383,0.4755894045159319,-0.22826282947820883,-0.12354522852272666,-0.10265492269446272,-0.6518579433658428,-0.417912582552414,0.06384901323418327,-0.3967645192768137,-0.29131079005371857,0.8613062272321225,-1.0839642060391366,0.04309508514240472,-0.4390800866390325,0.5572126623575777,0.12601197226717611,0.06384901323418327,-0.01926704960112091,-0.08178207009671594
2,945
Abnormality of salivation
13
40
2.156477
0.031046
Q15165,Q15233,P55011,P09651,Q92804,P35670,Q03252,Q96T58,P43243,P35637,Q8N0X7,Q01082,Q14739
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
0,517,232,359,180,272,452,208,424,115,251,440,29
1706,2313,2855,1164,739,2482,2556,359,931,1531,1907,976,115,272,1860,424,1481,711,982,2132,799,232,1679,514,2651,440,452,2607,2018,718,29,0,517,251,180,2188,2513,208,1187,700
-0.16537868346442086,-0.4814740099977851,-1.5935772487808675,0.08458639893558295,0.33218262437609547,-0.609138164405286,-0.6946624831235061,0.7197788815940095,0.20866925843125922,-0.08178207009671594,-0.2492604414061187,0.18802891238331532,1.618928329270631,0.8814712891547717,-0.22826282947820883,0.6386074394794051,-0.06092655176681376,0.352714297145243,0.18802891238331532,-0.35452613486786577,0.2910734677256283,1.0021895959906988,-0.14445310808685582,0.5368284738518867,-0.845166484742484,0.6182798801100748,0.597938284242163,-0.7590312945413134,-0.29131079005371857,0.352714297145243,3.655794126757704,7.623940234694683,0.5368284738518867,0.9418883330481125,1.1824164060489466,-0.37563575123099097,-0.6304875446399937,1.0824142734467934,0.08458639893558295,0.37323082292864296
2,945
Glycerolipid biosynthetic process
7
38
2.154527
0.031199
Q8WTV0,Q8NCC3,Q9UBF8,Q9NPH0,Q92643,Q6UWP7,Q969N2
Processes and pathways
GO Biological process
msigdb_gobp
32,7,16,17,52,211,152
2426,1049,1848,2799,1905,1343,2095,1860,2436,2722,1963,2897,1028,275,1496,211,7,1646,1830,2145,32,1604,1411,52,152,2656,394,675,2894,2446,1887,2587,17,1932,2836,16,1158,2363
-0.5665017880289501,0.14670037120281113,-0.22826282947820883,-1.2374993562115237,-0.2492604414061187,0.001537164702395684,-0.33343552863307785,-0.22826282947820883,-0.5665017880289501,-0.9967910215997426,-0.2702763842063141,-2.003165196484295,0.1673726504047501,0.8814712891547717,-0.06092655176681376,1.062376874281129,5.6091396582180515,-0.12354522852272666,-0.20728341801373437,-0.35452613486786577,3.5053441140537633,-0.10265492269446272,-0.01926704960112091,2.4958609523307893,1.2821160279306807,-0.845166484742484,0.6792207642978566,0.3937322929558605,-1.9801752339439305,-0.5665017880289501,-0.22826282947820883,-0.7160969742146781,4.4012629679932465,-0.2492604414061187,-1.414597701280427,4.4382543927063,0.10530734984835549,-0.5027007309924332
2,945
Blood vessel morphogenesis
18
74
2.153694
0.031264
Q96PU8,Q92990,P35613,P55011,Q9NWT6,Q5JRA6,P42224,P23634,Q86UE4,Q96AY3,P06576,P19174,Q9NZ08,O14964,Q96TA1,Q05397,P42785,Q4VCS5
Processes and pathways
GO Biological process
msigdb_gobp
330,328,161,232,204,172,238,240,81,19,332,53,22,358,88,217,27,349
358,400,1124,552,899,2786,1291,2123,862,2906,1091,332,1341,2259,2748,2055,2125,1854,53,532,2372,827,2518,240,2001,742,161,1134,238,27,2539,982,1354,232,2641,2103,2135,1597,1143,2878,217,492,664,1261,2460,1641,2066,1443,1262,454,1966,1027,349,172,2249,81,2768,328,1502,19,1649,1559,330,88,1001,384,2360,571,965,204,22,816,2903,1573
0.7197788815940095,0.6589210414523182,0.10530734984835549,0.49601692885848886,0.2292937886448734,-1.1935008981215134,0.022324505727692668,-0.35452613486786577,0.2499026019446144,-2.23448571265435,0.12601197226717611,0.7602824013383189,0.001537164702395684,-0.4390800866390325,-1.0839642060391366,-0.31236379292464844,-0.35452613486786577,-0.22826282947820883,2.4765850676126675,0.5164299238420278,-0.5239474963343811,0.27049579609526114,-0.6518579433658428,0.9620015287859891,-0.29131079005371857,0.33218262437609547,1.2422720024056197,0.10530734984835549,0.9821019275934442,3.6745672923672013,-0.6732495316326513,0.18802891238331532,0.001537164702395684,1.0021895959906988,-0.8235988933073602,-0.33343552863307785,-0.35452613486786577,-0.10265492269446272,0.10530734984835549,-1.7972284475701508,1.0423270044122548,0.5572126623575777,0.3937322929558605,0.04309508514240472,-0.587809634186986,-0.12354522852272666,-0.31236379292464844,-0.04008825025596049,0.04309508514240472,0.597938284242163,-0.2702763842063141,0.1673726504047501,0.7400374285311478,1.202380291141655,-0.417912582552414,2.0306629873686455,-1.1277013965550577,0.7805138743060999,-0.06092655176681376,4.34572728753516,-0.12354522852272666,-0.08178207009671594,0.7805138743060999,1.9525878342172756,0.18802891238331532,0.6995066854647584,-0.5027007309924332,0.49601692885848886,0.20866925843125922,1.1024392652871489,3.824492664661767,0.2910734677256283,-2.1185069787704807,-0.08178207009671594
2,945
Cell cycle mitotic
52
242
2.145292
0.03193
P00374,Q9BRT9,P25787,Q9BTX1,P31751,P20618,P62140,O95684,O75935,Q14739,P28070,Q07864,P52948,P30154,Q01105,P04350,P25205,Q86XL3,Q13042,Q13257,Q9Y619,P31350,P51665,O00231,O60763,Q13547,P50402,Q8NFH4,P42167,P35244,Q9Y6G9,P60900,Q8N1F7,P28072,Q5SRE5,Q7Z5K2,Q9H6D7,P61289,Q29RF7,P12270,Q8TEM1,P49721,Q9UPP1,Q14566,Q8WVM7,Q99436,Q8NFH5,Q08379,O75694,Q9NRF9,Q15154,Q9UQE7
Processes and pathways
Reactome Pathways
msigdb_reactome
1,524,3,259,262,261,403,24,154,29,31,162,295,294,170,293,422,46,179,564,50,555,561,550,551,54,315,320,556,438,591,196,327,69,325,458,203,580,455,578,353,469,223,227,365,504,501,360,485,247,379,526
1784,550,2398,2163,1523,1621,1337,2164,822,2535,681,895,856,2087,551,761,858,2258,2201,485,1622,154,1431,974,1904,24,1,790,2537,293,1668,2631,929,1246,900,1197,1624,2232,2202,1295,578,1434,975,1532,1672,2261,2262,2371,261,662,1248,2430,795,422,1249,3,1533,2483,2177,1799,1631,31,69,829,1200,2094,617,294,1801,555,262,1251,1713,1352,438,2434,641,1804,1536,2318,1478,1956,1957,2098,797,556,937,1301,1809,2099,2578,1589,938,2505,469,981,2101,1590,1539,315,2180,2181,561,295,2182,768,1306,712,196,2721,1862,599,580,620,403,1863,1638,983,1595,1488,1489,1596,800,2523,2104,2137,170,906,2244,162,360,1913,179,1210,564,2216,2105,1311,1146,54,836,2020,1642,718,2563,227,2106,1067,2866,948,29,1211,1314,2750,838,1495,1265,778,379,1149,1106,455,909,325,1070,1447,840,913,458,2893,46,2704,1368,327,1182,2510,2511,1450,320,501,1369,353,959,2187,365,2279,1689,2681,1833,919,1881,2849,504,1114,1034,607,1981,1693,1838,524,1506,648,259,811,1187,1609,1415,2530,1695,203,2822,2828,2079,1778,247,2361,2514,754,2646,1191,2082,1893,1234,2616,787,1423,1237,1566,1567,1568,223,526,700,2157,731,1572,732,1121,2515,2480,50,591
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2,945
Positive regulation of mrna processing
6
20
2.144401
0.032001
P62995,P52948,Q96E39,P38159,P98179,Q14011
Processes and pathways
GO Biological process
msigdb_gobp
197,295,173,109,61,93
1793,1092,1294,532,2373,109,295,197,61,872,946,346,93,2110,916,173,1834,695,1238,733
-0.20728341801373437,0.12601197226717611,0.022324505727692668,0.5164299238420278,-0.5239474963343811,1.6780316249499048,0.8411280257469278,1.1224519125778383,2.399390495804993,0.2499026019446144,0.20866925843125922,0.7400374285311478,1.8939254041622147,-0.33343552863307785,0.2292937886448734,1.202380291141655,-0.20728341801373437,0.37323082292864296,0.06384901323418327,0.352714297145243
2,945
Abnormal cerebral vascular morphology
11
60
2.13708
0.032591
Q969G3,P03886,P00403,Q9H845,P49257,O76024,P42224,O75844,Q04656,P21912,Q15056
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
257,2,166,70,231,76,238,80,148,119,255
702,1996,80,76,974,166,1127,790,2,2746,1668,2830,1243,2767,1014,1472,2831,530,661,1054,2372,827,119,1346,487,1477,2431,1630,707,1584,1750,2057,641,1955,2486,238,1056,1301,231,982,2269,1022,1143,440,2017,148,1965,688,255,646,1322,257,1880,2860,70,2765,1419,1617,260,2647
0.352714297145243,-0.29131079005371857,2.0501568052051606,2.0891147678360613,0.18802891238331532,1.2223321368163933,0.10530734984835549,0.2910734677256283,7.077162194942315,-1.0839642060391366,-0.14445310808685582,-1.3923607141779688,0.04309508514240472,-1.1277013965550577,0.1673726504047501,-0.06092655176681376,-1.3923607141779688,0.5164299238420278,0.3937322929558605,0.14670037120281113,-0.5239474963343811,0.27049579609526114,1.5794717175274886,0.001537164702395684,0.5572126623575777,-0.06092655176681376,-0.5665017880289501,-0.12354522852272666,0.352714297145243,-0.10265492269446272,-0.18632207833549766,-0.31236379292464844,0.4142187974298949,-0.2702763842063141,-0.609138164405286,0.9821019275934442,0.14670037120281113,0.022324505727692668,1.0021895959906988,0.18802891238331532,-0.4390800866390325,0.1673726504047501,0.10530734984835549,0.6182798801100748,-0.29131079005371857,1.3020203038267055,-0.2702763842063141,0.37323082292864296,0.921762273203752,0.4142187974298949,0.022324505727692668,0.921762273203752,-0.22826282947820883,-1.6386272017792467,2.2057541946060866,-1.105820052560868,-0.01926704960112091,-0.10265492269446272,0.921762273203752,-0.8235988933073602
2,945
Signaling by hedgehog
15
55
2.135408
0.032728
P10644,P25787,Q9UMX1,Q86TM6,P60900,P28072,Q99436,Q9GZP9,P04350,P20618,P07237,P51665,O00231,P49721,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
530,3,260,520,196,69,504,369,293,261,418,561,550,469,31
550,2398,2163,1523,1337,1622,293,418,530,1475,1672,261,1249,3,1533,2483,1631,31,69,829,2318,1809,2578,1479,2505,469,1539,561,1306,1679,196,580,1863,1638,1595,2523,2244,1210,1146,2020,947,2750,1265,2110,520,2795,2279,504,1114,811,1187,369,1237,260,1568
0.49601692885848886,-0.5452144624387532,-0.37563575123099097,-0.08178207009671594,0.001537164702395684,-0.12354522852272666,0.8411280257469278,0.6386074394794051,0.5164299238420278,-0.06092655176681376,-0.14445310808685582,0.9016232814114782,0.04309508514240472,6.86435802761024,-0.08178207009671594,-0.609138164405286,-0.12354522852272666,3.5053441140537633,2.2639439873853995,0.27049579609526114,-0.4814740099977851,-0.20728341801373437,-0.7160969742146781,-0.06092655176681376,-0.6304875446399937,0.5775825719273033,-0.08178207009671594,0.49601692885848886,0.022324505727692668,-0.14445310808685582,1.1224519125778383,0.4755894045159319,-0.22826282947820883,-0.12354522852272666,-0.10265492269446272,-0.6518579433658428,-0.417912582552414,0.06384901323418327,0.10530734984835549,-0.29131079005371857,0.20866925843125922,-1.0839642060391366,0.04309508514240472,-0.33343552863307785,0.5368284738518867,-1.2154867397644784,-0.4390800866390325,0.5572126623575777,0.12601197226717611,0.2910734677256283,0.08458639893558295,0.7197788815940095,0.06384901323418327,0.921762273203752,-0.08178207009671594
2,945
Regulation of pten stability and activity
11
42
2.132468
0.032968
P49721,P25787,P60900,P28072,Q99436,P31751,P20618,P51665,O00231,P46934,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
469,3,196,69,504,262,261,561,550,558,31
550,2398,2163,1523,1337,1622,1672,2371,261,1249,3,1533,2483,1631,31,69,829,262,2318,1809,558,2578,2505,469,561,1306,196,580,1863,1638,1595,2104,2244,1210,2750,1265,2279,504,1114,1237,1424,1568
0.49601692885848886,-0.5452144624387532,-0.37563575123099097,-0.08178207009671594,0.001537164702395684,-0.12354522852272666,-0.14445310808685582,-0.5239474963343811,0.9016232814114782,0.04309508514240472,6.86435802761024,-0.08178207009671594,-0.609138164405286,-0.12354522852272666,3.5053441140537633,2.2639439873853995,0.27049579609526114,0.9016232814114782,-0.4814740099977851,-0.20728341801373437,0.49601692885848886,-0.7160969742146781,-0.6304875446399937,0.5775825719273033,0.49601692885848886,0.022324505727692668,1.1224519125778383,0.4755894045159319,-0.22826282947820883,-0.12354522852272666,-0.10265492269446272,-0.33343552863307785,-0.417912582552414,0.06384901323418327,-1.0839642060391366,0.04309508514240472,-0.4390800866390325,0.5572126623575777,0.12601197226717611,0.06384901323418327,-0.01926704960112091,-0.08178207009671594
2,945
Generalized muscle weakness
9
30
2.132246
0.032987
Q15165,Q9H845,P09651,Q92804,P35637,P21912,Q5JTZ9,O95831,Q02809
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
0,70,359,180,115,119,350,89,404
1164,89,1245,2482,359,2831,1851,2456,119,2127,1750,115,1808,424,1590,711,2346,1679,1960,404,2018,718,2638,0,350,180,70,2754,700,1520
0.08458639893558295,1.9330438639514882,0.04309508514240472,-0.609138164405286,0.7197788815940095,-1.3923607141779688,-0.22826282947820883,-0.587809634186986,1.5794717175274886,-0.35452613486786577,-0.18632207833549766,1.618928329270631,-0.20728341801373437,0.6386074394794051,-0.10265492269446272,0.352714297145243,-0.5027007309924332,-0.14445310808685582,-0.2702763842063141,0.6589210414523182,-0.29131079005371857,0.352714297145243,-0.8020539598800626,7.623940234694683,0.7400374285311478,1.1824164060489466,2.2057541946060866,-1.0839642060391366,0.37323082292864296,-0.06092655176681376
2,945
Cellular response to insulin stimulus
18
48
2.121263
0.0339
O60763,Q9HCD5,P61026,P31751,Q92922,P43490,P42224,Q9UQB8,P61981,Q15043,P22413,Q8WWQ0,Q9BZF1,P62993,Q7L576,Q9H1E3,P20020,P25054
Processes and pathways
GO Biological process
msigdb_gobp
551,269,323,262,568,43,238,47,620,151,487,672,118,491,604,354,314,533
1662,1047,1123,703,551,1470,2229,1342,2202,2055,1129,2172,1296,314,487,533,262,238,43,2100,1591,1539,2521,2377,2721,323,620,491,1721,2459,2066,2139,151,1028,1364,669,604,672,1500,568,2030,1370,118,354,269,1461,47,2159
-0.14445310808685582,0.14670037120281113,0.10530734984835549,0.352714297145243,0.49601692885848886,-0.06092655176681376,-0.417912582552414,0.001537164702395684,-0.3967645192768137,-0.31236379292464844,0.10530734984835549,-0.37563575123099097,0.022324505727692668,0.8007319209650764,0.5572126623575777,0.5164299238420278,0.9016232814114782,0.9821019275934442,2.860424771989179,-0.33343552863307785,-0.10265492269446272,-0.08178207009671594,-0.6518579433658428,-0.5239474963343811,-0.9967910215997426,0.7805138743060999,0.4346904255440359,0.5572126623575777,-0.16537868346442086,-0.587809634186986,-0.31236379292464844,-0.35452613486786577,1.2821160279306807,0.1673726504047501,0.001537164702395684,0.3937322929558605,0.4551472654983724,0.3937322929558605,-0.06092655176681376,0.49601692885848886,-0.29131079005371857,0.001537164702395684,1.5992054978277717,0.7400374285311478,0.9016232814114782,-0.04008825025596049,2.688128608527772,-0.35452613486786577
2,945
Regulation of response to stress
59
223
2.121195
0.033905
Q96IZ0,P00374,P67809,Q86TM6,P61978,Q15233,O43464,O60885,Q13177,Q9UNS1,Q04656,Q8N163,Q9NZ08,Q9UBU8,Q9Y4L1,Q9Y5Z4,O95881,O95251,Q9Y4E8,Q03426,P30040,P28070,O75116,Q07021,Q9NYF8,P04439,Q96S55,P07237,O60313,P19174,P43243,Q7Z4V5,Q96PK6,P51114,P19474,O00330,Q96QD8,P60900,Q8N2K0,Q96G23,O76024,O75844,P23246,Q9UNS2,P32119,Q05397,Q96FV9,P78318,Q16625,P12956,P55011,Q9NUD5,P42224,P23634,P35637,Q9UIV1,P46379,P10586,Q06787
Processes and pathways
GO Biological process
msigdb_gobp
128,1,129,520,134,517,510,511,516,547,148,277,22,278,291,549,149,155,290,405,534,31,400,178,306,175,303,418,174,53,424,183,188,439,186,193,66,196,460,72,76,80,333,480,210,217,476,471,348,343,232,234,238,240,115,117,489,249,254
852,193,854,701,821,1524,510,2292,1899,2649,174,2650,682,511,400,761,1948,2201,1622,80,1949,2166,76,1007,859,553,1579,2865,155,149,1905,1796,1165,1,2825,739,790,2746,862,2690,175,1668,2906,1091,2403,763,418,900,2670,1433,1197,1128,1342,249,2575,2886,1295,343,1530,1474,2913,1094,975,1532,933,1296,53,186,1855,2372,333,579,240,1096,1249,1097,2177,31,2094,865,534,2207,210,2058,2001,115,1805,2130,238,1859,1301,424,489,1676,980,1716,1539,439,686,1717,597,2009,2319,1959,232,1022,1816,941,2405,196,2103,1257,1486,2183,1759,134,2742,129,471,1721,1026,405,537,148,217,2459,254,178,2460,2911,1492,1493,2323,945,516,717,1360,1066,2609,1263,1173,776,2884,2068,517,2923,2140,1966,1918,666,1027,1919,348,2248,1727,667,2249,1405,1875,913,183,520,914,1368,2414,277,460,1222,806,1499,722,1879,1501,1606,1503,1649,476,1735,72,1372,128,1413,1692,188,1883,66,784,303,2753,2682,1980,2073,888,1775,2189,2391,1038,2151,2550,234,755,1458,2614,2834,2905,306,22,1002,1462,278,2394,117,2199,817,2336,1936,547,480,851,2364,290,291,549
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2,945
Constipation
24
88
2.121188
0.033906
P03886,P61978,O43464,P37268,Q03164,P55795,P42892,Q04656,P62140,P16435,P25054,P00403,Q01082,O76024,Q9H270,Q96T58,Q03252,P78318,Q8TAA9,P55011,Q13423,P21912,Q8N0X7,Q15056
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
2,134,510,12,13,514,264,148,403,402,533,166,440,76,339,208,452,471,221,232,112,119,251,255
510,702,2650,2640,76,2453,1339,1011,166,2,2746,2830,1243,2231,1293,2456,402,662,2372,119,1391,533,1750,641,2002,12,1019,2486,264,902,1538,982,1756,769,232,514,2062,134,403,1760,471,1143,2698,440,2722,13,452,537,148,2607,908,986,112,873,1067,255,2643,1177,2249,2110,1497,2817,1875,251,1182,1183,917,2666,221,1604,884,2512,1879,2188,626,784,208,2682,2075,339,1455,2191,1456,2628,923,1617,787,2647
0.5368284738518867,0.352714297145243,-0.845166484742484,-0.8235988933073602,2.0891147678360613,-0.587809634186986,0.001537164702395684,0.1673726504047501,1.2223321368163933,7.077162194942315,-1.0839642060391366,-1.3923607141779688,0.04309508514240472,-0.417912582552414,0.022324505727692668,-0.587809634186986,0.6589210414523182,0.3937322929558605,-0.5239474963343811,1.5794717175274886,-0.01926704960112091,0.5164299238420278,-0.18632207833549766,0.4142187974298949,-0.29131079005371857,4.770037134790452,0.1673726504047501,-0.609138164405286,0.9016232814114782,0.2292937886448734,-0.08178207009671594,0.18802891238331532,-0.18632207833549766,0.3116357123478239,1.0021895959906988,0.5368284738518867,-0.31236379292464844,1.4212012137589964,0.6589210414523182,-0.18632207833549766,0.5775825719273033,0.10530734984835549,-0.9316674210504035,0.6182798801100748,-0.9967910215997426,4.659667932546476,0.597938284242163,0.5164299238420278,1.3020203038267055,-0.7590312945413134,0.2292937886448734,0.18802891238331532,1.6583413438014383,0.2499026019446144,0.14670037120281113,0.921762273203752,-0.8235988933073602,0.08458639893558295,-0.417912582552414,-0.33343552863307785,-0.06092655176681376,-1.3037005802478918,-0.22826282947820883,0.9418883330481125,0.08458639893558295,0.08458639893558295,0.2292937886448734,-0.8667569312531026,1.0423270044122548,-0.10265492269446272,0.2499026019446144,-0.6304875446399937,-0.22826282947820883,-0.37563575123099097,0.4346904255440359,0.3116357123478239,1.0824142734467934,-0.8883704331508439,-0.31236379292464844,0.7602824013383189,-0.04008825025596049,-0.37563575123099097,-0.04008825025596049,-0.7805314905603624,0.2292937886448734,-0.10265492269446272,0.3116357123478239,-0.8235988933073602
2,945
Helicase
7
21
2.118758
0.034111
Q14566,Q92620,P12956,Q6P158,P25205,Q96S55,Q14562
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
227,229,343,519,422,303,56
1790,1048,343,1530,422,1800,1251,1352,1753,981,1492,56,227,519,1216,2444,1111,229,1269,303,570
-0.20728341801373437,0.14670037120281113,0.7400374285311478,-0.08178207009671594,0.6386074394794051,-0.20728341801373437,0.04309508514240472,0.001537164702395684,-0.18632207833549766,0.18802891238331532,-0.06092655176681376,2.4573001148610345,1.0222645998514908,0.5368284738518867,0.06384901323418327,-0.5665017880289501,0.12601197226717611,1.0222645998514908,0.04309508514240472,0.8209366140972024,0.49601692885848886
2,945
Transcriptional regulation by runx2
8
53
2.110754
0.034793
P25787,P60900,P28072,P31751,P20618,P42224,Q96PK6,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
3,196,69,262,261,238,188,31
550,2398,2163,1523,1337,1622,929,2670,2202,1434,1672,261,1249,3,1533,2483,2177,1631,31,69,829,2094,262,2318,238,1809,2578,2505,469,1539,561,1306,196,580,1863,1638,1595,2523,2244,2460,1210,2216,2020,283,2750,1265,2279,188,504,1114,1237,1424,1568
0.49601692885848886,-0.5452144624387532,-0.37563575123099097,-0.08178207009671594,0.001537164702395684,-0.12354522852272666,0.20866925843125922,-0.8883704331508439,-0.3967645192768137,-0.04008825025596049,-0.14445310808685582,0.9016232814114782,0.04309508514240472,6.86435802761024,-0.08178207009671594,-0.609138164405286,-0.37563575123099097,-0.12354522852272666,3.5053441140537633,2.2639439873853995,0.27049579609526114,-0.33343552863307785,0.9016232814114782,-0.4814740099977851,0.9821019275934442,-0.20728341801373437,-0.7160969742146781,-0.6304875446399937,0.5775825719273033,-0.08178207009671594,0.49601692885848886,0.022324505727692668,1.1224519125778383,0.4755894045159319,-0.22826282947820883,-0.12354522852272666,-0.10265492269446272,-0.6518579433658428,-0.417912582552414,-0.587809634186986,0.06384901323418327,-0.3967645192768137,-0.29131079005371857,0.8613062272321225,-1.0839642060391366,0.04309508514240472,-0.4390800866390325,1.142452277500605,0.5572126623575777,0.12601197226717611,0.06384901323418327,-0.01926704960112091,-0.08178207009671594
2,945
Regulation of ras by gaps
10
40
2.110685
0.034799
P25787,P60900,P28072,Q99436,P20618,P51665,O00231,Q9UJF2,P49721,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
3,196,69,504,261,561,550,357,469,31
550,2398,2163,1523,1337,1622,1672,261,827,1249,3,1533,2483,1631,31,69,829,2318,1809,2578,2505,469,561,1306,196,580,1863,1638,1595,2244,1210,947,2750,1265,2279,504,1114,357,1237,1568
0.49601692885848886,-0.5452144624387532,-0.37563575123099097,-0.08178207009671594,0.001537164702395684,-0.12354522852272666,-0.14445310808685582,0.9016232814114782,0.27049579609526114,0.04309508514240472,6.86435802761024,-0.08178207009671594,-0.609138164405286,-0.12354522852272666,3.5053441140537633,2.2639439873853995,0.27049579609526114,-0.4814740099977851,-0.20728341801373437,-0.7160969742146781,-0.6304875446399937,0.5775825719273033,0.49601692885848886,0.022324505727692668,1.1224519125778383,0.4755894045159319,-0.22826282947820883,-0.12354522852272666,-0.10265492269446272,-0.417912582552414,0.06384901323418327,0.20866925843125922,-1.0839642060391366,0.04309508514240472,-0.4390800866390325,0.5572126623575777,0.12601197226717611,0.7400374285311478,0.06384901323418327,-0.08178207009671594
2,945
Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen
12
26
2.104821
0.035307
P30519,O15460,Q16850,Q32P28,Q9NWT6,P07237,P13674,Q8NB78,P61457,Q02809,P16435,Q9UPP1
Functions
GO Molecular function
msigdb_gomf
96,100,101,136,204,418,176,21,86,404,402,223
819,100,2650,2427,825,738,418,2259,176,402,96,86,404,642,1313,2847,101,136,1406,442,1180,21,2548,2861,204,223
0.27049579609526114,1.7763226939226555,-0.845166484742484,-0.5665017880289501,0.27049579609526114,0.33218262437609547,0.6386074394794051,-0.4390800866390325,1.1824164060489466,0.6589210414523182,1.8547659602664823,1.9525878342172756,0.6589210414523182,0.4142187974298949,0.022324505727692668,-1.5262302338877283,1.7763226939226555,1.4013665868313239,-0.01926704960112091,0.6182798801100748,0.08458639893558295,4.01126221185754,-0.6732495316326513,-1.6386272017792467,1.1024392652871489,1.0423270044122548
2,945
Cellular response to endogenous stimulus
59
214
2.10091
0.035649
Q9HCD5,P31751,Q13177,Q9H7B4,Q9UNS1,Q04656,Q15043,Q96KQ7,Q8WWQ0,P62942,Q8TDD1,Q96EV8,P42785,Q6ZWJ1,O95429,Q06330,P25054,P19338,Q9Y4E8,P16435,O75116,Q92922,P43490,Q9NS86,Q9UQ13,Q9UQB8,P19174,Q13547,O60763,Q02790,O94813,P20020,P46934,P61026,P61960,P08670,O00400,Q9H270,O75844,Q99729,Q14103,O95831,Q7L576,Q05397,Q9H1E3,O00410,Q8IZL8,P14625,Q05D32,P42224,O15173,P23634,P61981,P35241,Q9BZF1,P22413,Q8N0X7,P62993,Q9GZZ9
Processes and pathways
GO Biological process
msigdb_gobp
269,262,516,14,547,148,151,674,672,25,671,540,27,669,156,664,533,532,290,402,400,568,43,305,308,47,53,54,551,58,552,314,558,323,581,205,446,339,80,209,335,89,604,217,354,592,352,468,345,238,237,240,620,618,118,487,251,491,650
2288,1662,446,592,820,1047,1744,1787,2851,1336,237,1123,1794,2650,703,1994,551,400,1901,80,552,859,1579,156,89,862,1668,1090,1091,2600,1470,2229,2670,1197,205,1472,1342,1093,1294,2202,2055,468,1129,2125,1094,402,2172,1343,933,1296,53,532,314,2372,487,1628,240,533,1435,2484,2177,2557,707,2820,2094,262,2095,2096,1352,708,866,2001,977,618,2003,1134,936,238,1859,1675,27,43,2099,2520,1715,558,1136,2100,2504,1591,1539,1058,2521,1717,905,1485,2377,2721,323,1258,2183,2135,581,620,1596,1639,25,491,2104,1598,1721,2348,1722,58,148,1491,2607,217,345,2459,664,1723,2066,2859,516,987,2139,2216,1763,1262,1147,54,946,335,2245,1866,1067,1314,151,2107,1726,1966,1362,2326,1918,666,1028,1727,2141,1364,1030,669,604,1320,1368,352,251,2386,2511,671,672,2029,1500,1688,2467,918,2529,568,2030,1606,2188,994,1370,1503,540,1372,1559,674,784,2682,887,2332,209,2796,118,889,2150,650,354,339,1510,1278,965,14,2447,269,2151,305,2613,1461,1421,1119,1424,1936,547,1782,308,47,893,732,2200,290,2903,2159
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2,945
Negative regulation of cell cell adhesion
6
15
2.096556
0.036033
Q96IZ0,Q13951,P49593,Q5JRA6,P32119,Q05397
Processes and pathways
GO Biological process
msigdb_gobp
128,283,202,172,210,217
862,1128,530,210,618,1675,202,1717,217,283,1264,172,328,128,2333
0.2499026019446144,0.10530734984835549,0.5164299238420278,1.062376874281129,0.4346904255440359,-0.14445310808685582,1.1024392652871489,-0.16537868346442086,1.0423270044122548,0.8613062272321225,0.04309508514240472,1.202380291141655,0.7805138743060999,1.4608362743298053,-0.4814740099977851
2,945
Mrna processing
68
236
2.090499
0.036573
P31943,O75934,Q99459,P67809,Q9H0D6,P61978,Q15459,Q15233,Q9Y4C8,P98175,Q07666,Q8N163,Q86U42,Q16629,P52272,P07910,P19338,Q08170,Q8WWY3,Q6PD62,Q8IWZ8,O43390,P52948,Q6PJT7,Q96E39,Q07021,Q9ULX6,Q13151,P51991,Q8N684,Q14562,Q96PK6,P51114,P98179,Q9Y5S9,Q96PU8,P31942,Q9Y2W2,P62995,Q5BKZ1,Q9UJV9,Q07955,O43290,Q13242,Q92797,P23246,Q13123,O60506,Q96FV9,Q14011,Q92620,Q13595,P52597,P22626,Q96MU7,Q96DF8,Q9BWF3,P38159,P09651,Q15637,Q13435,Q8WVV9,P41223,O75150,Q5VT52,Q6UN15,Q06787,O75494
Processes and pathways
GO Biological process
msigdb_gobp
375,374,523,129,395,134,518,517,527,515,273,277,276,407,535,401,532,163,432,565,566,169,295,428,173,178,573,563,182,444,56,188,439,61,465,330,195,464,197,198,462,324,447,77,207,333,453,215,476,93,229,346,225,224,368,367,239,109,359,363,494,242,488,484,497,125,254,127
1380,968,1786,1787,1428,1790,971,576,447,169,2648,1992,1005,1382,1793,1794,2400,636,2650,215,682,484,1901,1006,823,127,1125,1050,374,1051,1387,2428,2167,401,930,1092,863,359,1167,1294,660,1670,2171,933,1054,1345,532,1248,224,333,2092,1392,2373,935,195,375,2096,109,1585,2003,488,1020,1480,766,439,686,182,535,225,663,295,1438,1022,1256,2241,134,1680,1142,2793,1440,2663,197,129,2878,871,515,61,1722,2642,2272,2304,254,178,273,324,163,1492,872,1494,835,1100,562,1442,453,2018,563,77,2139,717,494,2410,946,346,1263,93,2245,1822,1601,56,1174,2067,1725,1765,517,1766,1726,518,363,407,1212,1176,910,2275,2070,198,2920,1446,497,2412,644,876,1729,1071,2443,912,2752,2110,1873,1406,565,428,125,1407,1215,2072,2112,276,1267,2703,566,1686,2693,277,1217,444,916,2251,1185,806,1831,242,432,2827,1225,229,207,918,1226,1453,783,2584,367,2566,173,1834,476,694,1412,368,2388,2470,188,330,2389,523,1608,239,1652,2334,2870,395,1154,848,695,1986,2447,2192,1698,1700,891,2081,1703,1331,755,631,1742,1332,2933,462,1333,1236,788,573,1238,1937,733,464,1240,2697,1619,634,613,2200,527,2812,465
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2,945
Metabolism of polyamines
10
39
2.086279
0.036953
P25787,P60900,P28072,Q99436,P20618,P51665,O00231,Q9H2H9,P49721,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
3,196,69,504,261,561,550,384,469,31
550,2398,2163,1523,1337,1622,1672,2317,261,1249,3,1533,2483,1631,31,69,829,2318,1809,2578,2505,469,561,1306,196,580,1863,1638,1595,2244,1210,2750,1265,2279,504,1114,384,1237,1568
0.49601692885848886,-0.5452144624387532,-0.37563575123099097,-0.08178207009671594,0.001537164702395684,-0.12354522852272666,-0.14445310808685582,-0.4814740099977851,0.9016232814114782,0.04309508514240472,6.86435802761024,-0.08178207009671594,-0.609138164405286,-0.12354522852272666,3.5053441140537633,2.2639439873853995,0.27049579609526114,-0.4814740099977851,-0.20728341801373437,-0.7160969742146781,-0.6304875446399937,0.5775825719273033,0.49601692885848886,0.022324505727692668,1.1224519125778383,0.4755894045159319,-0.22826282947820883,-0.12354522852272666,-0.10265492269446272,-0.417912582552414,0.06384901323418327,-1.0839642060391366,0.04309508514240472,-0.4390800866390325,0.5572126623575777,0.12601197226717611,0.6995066854647584,0.06384901323418327,-0.08178207009671594
2,945
Metalloprotease
8
28
2.085941
0.036984
Q96E52,Q5JRX3,P42892,P55786,O75844,Q9UIQ6,Q9NZ08,O43847
Functions
Protein Atlas Molecular function
protein_atlas_molecular_function
97,266,264,45,80,116,22,312
2163,312,1383,80,2660,1009,1850,2714,1129,264,1484,45,266,2788,1556,1501,97,2567,997,1274,383,1738,2686,1654,2495,22,116,1044
-0.37563575123099097,0.8007319209650764,-0.01926704960112091,2.0501568052051606,-0.8667569312531026,0.1673726504047501,-0.22826282947820883,-0.9750591188791282,0.10530734984835549,0.9016232814114782,-0.06092655176681376,2.841314827134973,0.9016232814114782,-1.1935008981215134,-0.08178207009671594,-0.06092655176681376,1.8547659602664823,-0.6946624831235061,0.18802891238331532,0.04309508514240472,0.6995066854647584,-0.16537868346442086,-0.8883704331508439,-0.12354522852272666,-0.609138164405286,3.824492664661767,1.618928329270631,0.1673726504047501
2,945
Phenotypic variability
17
96
2.085
0.037069
O00330,P00374,P03886,Q969G3,Q9UMX1,P00403,O14979,Q70HW3,P42224,P35270,P00846,P21912,O60313,Q8TD16,Q92733,Q6PI48,Q06787
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
193,1,2,257,260,166,132,10,238,271,18,119,174,87,124,286,254
193,678,132,680,174,1049,1386,973,1527,899,1,166,18,790,2,293,1245,2932,1014,2230,2556,826,2927,119,2430,1352,2001,271,2002,1955,1018,1908,238,1301,424,2503,1254,981,1590,1481,711,1756,2672,1757,1679,2377,712,2651,772,944,985,254,1065,1146,2929,406,1361,1444,688,2711,2723,2729,721,1873,2898,286,10,647,87,432,124,257,747,811,1187,461,2191,1155,2754,2285,1702,2904,755,1655,2599,1513,2197,525,462,260,2047,654,1516,2083,1044,1335
1.1224519125778383,0.37323082292864296,1.4212012137589964,0.37323082292864296,1.1824164060489466,0.14670037120281113,-0.01926704960112091,0.18802891238331532,-0.08178207009671594,0.2292937886448734,7.448017023011698,1.2223321368163933,4.364245678303629,0.2910734677256283,7.077162194942315,0.8411280257469278,0.04309508514240472,-3.890742390654541,0.1673726504047501,-0.417912582552414,-0.6946624831235061,0.27049579609526114,-3.4009820894719756,1.5794717175274886,-0.5665017880289501,0.001537164702395684,-0.29131079005371857,0.8814712891547717,-0.29131079005371857,-0.2702763842063141,0.1673726504047501,-0.2492604414061187,0.9821019275934442,0.022324505727692668,0.6386074394794051,-0.6304875446399937,0.04309508514240472,0.18802891238331532,-0.10265492269446272,-0.06092655176681376,0.352714297145243,-0.18632207833549766,-0.8883704331508439,-0.18632207833549766,-0.14445310808685582,-0.5239474963343811,0.352714297145243,-0.845166484742484,0.3116357123478239,0.20866925843125922,0.18802891238331532,0.921762273203752,0.14670037120281113,0.10530734984835549,-3.571580495971794,0.6589210414523182,0.001537164702395684,-0.04008825025596049,0.37323082292864296,-0.9533513246189271,-0.9967910215997426,-1.01854725430779,0.352714297145243,-0.22826282947820883,-2.0261815359580435,0.8613062272321225,5.045004847981975,0.4142187974298949,1.9525878342172756,0.6386074394794051,1.5202041804528397,0.921762273203752,0.33218262437609547,0.2910734677256283,0.08458639893558295,0.597938284242163,-0.37563575123099097,0.10530734984835549,-1.0839642060391366,-0.4390800866390325,-0.14445310808685582,-2.141652463609769,0.33218262437609547,-0.12354522852272666,-0.7375531840373677,-0.06092655176681376,-0.37563575123099097,0.5368284738518867,0.597938284242163,0.921762273203752,-0.29131079005371857,0.4142187974298949,-0.06092655176681376,-0.31236379292464844,0.1673726504047501,0.022324505727692668
2,945
Muscle structure development
21
94
2.080941
0.037439
P67809,Q14012,P11310,Q9H7B4,Q7Z406,P62942,P80723,P50402,Q13547,Q7Z4V5,P51114,P16220,Q96PU8,Q92990,Q9P2K5,Q9NWT6,O75844,O75179,Q96TA1,Q9BWF3,Q9BYT8
Processes and pathways
GO Biological process
msigdb_gobp
129,393,11,14,408,25,301,315,54,183,439,437,330,328,199,204,80,331,88,239,383
734,680,448,2650,1847,331,2401,80,972,1007,553,790,2690,1091,929,1292,530,11,1852,792,2787,2236,437,683,1343,933,1854,827,2484,1392,707,2056,2001,742,1859,1675,559,1591,315,439,982,2299,2211,1259,2135,25,129,301,2652,2348,1722,664,986,54,2381,393,775,1965,2884,2638,1966,1362,1027,1727,719,1407,408,183,2679,1368,2511,1975,918,328,2356,330,88,887,1560,239,383,1375,1278,14,2447,1700,1564,204,1190,199,2874,1938,1044,2118
0.33218262437609547,0.37323082292864296,0.597938284242163,-0.845166484742484,-0.22826282947820883,0.7602824013383189,-0.5452144624387532,2.0501568052051606,0.18802891238331532,0.1673726504047501,0.49601692885848886,0.2910734677256283,-0.9100071940702691,0.12601197226717611,0.20866925843125922,0.022324505727692668,0.5164299238420278,4.9168542761704375,-0.22826282947820883,0.2910734677256283,-1.1935008981215134,-0.417912582552414,0.6182798801100748,0.37323082292864296,0.001537164702395684,0.20866925843125922,-0.22826282947820883,0.27049579609526114,-0.609138164405286,-0.01926704960112091,0.352714297145243,-0.31236379292464844,-0.29131079005371857,0.33218262437609547,-0.22826282947820883,-0.14445310808685582,0.49601692885848886,-0.10265492269446272,0.8007319209650764,0.6182798801100748,0.18802891238331532,-0.4602671791946553,-0.3967645192768137,0.04309508514240472,-0.35452613486786577,3.768324465880385,1.4410244250244986,0.8209366140972024,-0.845166484742484,-0.5027007309924332,-0.16537868346442086,0.3937322929558605,0.18802891238331532,2.4765850676126675,-0.5239474963343811,0.6792207642978566,0.3116357123478239,-0.2702763842063141,-1.8656278024761768,-0.8020539598800626,-0.2702763842063141,0.001537164702395684,0.1673726504047501,-0.16537868346442086,0.352714297145243,-0.01926704960112091,0.6589210414523182,1.1624404216515005,-0.8883704331508439,0.001537164702395684,-0.6304875446399937,-0.2702763842063141,0.2292937886448734,0.7805138743060999,-0.5027007309924332,0.7805138743060999,1.9525878342172756,0.2499026019446144,-0.08178207009671594,0.9821019275934442,0.6995066854647584,0.001537164702395684,0.04309508514240472,4.62282865259948,-0.5665017880289501,-0.14445310808685582,-0.08178207009671594,1.1024392652871489,0.08458639893558295,1.1224519125778383,-1.751769488181549,-0.2492604414061187,0.1673726504047501,-0.33343552863307785
2,945
Peptidyl proline hydroxylation
6
7
2.078587
0.037655
O15460,Q96HE7,Q32P28,O75718,P07237,P13674
Processes and pathways
GO Biological process
msigdb_gobp
100,586,136,388,418,176
100,388,418,176,583,136,586
1.7763226939226555,0.6792207642978566,0.6386074394794051,1.1824164060489466,0.4755894045159319,1.4013665868313239,0.4755894045159319
2,945
Atpase coupled cation transmembrane transporter activity
8
17
2.078068
0.037703
P21281,P05026,P23634,P35670,P06576,Q04656,Q9HD20,P20020
Functions
GO Molecular function
msigdb_gomf
105,201,240,272,332,148,253,314
1090,201,332,683,314,105,2174,240,272,1252,1018,2522,2561,148,253,2041,387
0.12601197226717611,1.1024392652871489,0.7602824013383189,0.37323082292864296,0.8007319209650764,1.7370381436593936,-0.37563575123099097,0.9620015287859891,0.8814712891547717,0.04309508514240472,0.1673726504047501,-0.6518579433658428,-0.6946624831235061,1.3020203038267055,0.9418883330481125,-0.29131079005371857,0.6995066854647584
2,945
Peptidyl lysine modification
19
78
2.065093
0.038914
Q14012,O60885,Q03164,Q9H7B4,Q96AY3,Q9H267,Q04656,Q9UBU8,O95251,Q02809,P16435,Q01105,Q9Y6J9,O95696,O75844,Q92791,Q9NPA8,Q9NRF9,P46379
Processes and pathways
GO Biological process
msigdb_gobp
393,511,13,14,19,545,148,278,155,404,402,170,466,194,80,92,506,247,489
735,1574,1123,2650,511,1948,2687,80,155,194,1290,1796,1165,790,1748,2294,1711,402,1345,2484,2177,2001,2099,489,1538,1590,982,2132,1485,2013,170,404,13,148,1360,1310,946,1101,393,1173,2884,2867,1967,667,565,2384,1407,1075,1368,2467,92,994,19,674,1836,2682,2548,2034,1231,1653,2393,2695,545,1739,14,506,247,920,1613,1615,1003,1463,278,2045,851,2364,924,466
0.33218262437609547,-0.10265492269446272,0.10530734984835549,-0.845166484742484,0.5368284738518867,-0.2702763842063141,-0.9100071940702691,2.0501568052051606,1.262199946694982,1.1224519125778383,0.022324505727692668,-0.20728341801373437,0.08458639893558295,0.2910734677256283,-0.18632207833549766,-0.4602671791946553,-0.16537868346442086,0.6589210414523182,0.001537164702395684,-0.609138164405286,-0.37563575123099097,-0.29131079005371857,-0.33343552863307785,0.5572126623575777,-0.08178207009671594,-0.10265492269446272,0.18802891238331532,-0.35452613486786577,-0.06092655176681376,-0.29131079005371857,1.202380291141655,0.6589210414523182,4.659667932546476,1.3020203038267055,0.001537164702395684,0.022324505727692668,0.20866925843125922,0.12601197226717611,0.6792207642978566,0.08458639893558295,-1.8656278024761768,-1.6837963753761036,-0.2702763842063141,0.3937322929558605,0.49601692885848886,-0.5239474963343811,-0.01926704960112091,0.14670037120281113,0.001537164702395684,-0.587809634186986,1.9134897350999418,0.18802891238331532,4.34572728753516,0.3937322929558605,-0.20728341801373437,-0.8883704331508439,-0.6732495316326513,-0.29131079005371857,0.06384901323418327,-0.12354522852272666,-0.5239474963343811,-0.9100071940702691,0.5164299238420278,-0.16537868346442086,4.62282865259948,0.5572126623575777,0.9620015287859891,0.2292937886448734,-0.10265492269446272,-0.10265492269446272,0.18802891238331532,-0.04008825025596049,0.8814712891547717,-0.29131079005371857,0.27049579609526114,-0.5027007309924332,0.2292937886448734,0.597938284242163
2,945
RNA-binding
79
334
2.065045
0.038919
P00374,Q99459,Q8WUA2,Q15233,P55795,P98175,Q9UPY3,Q9BQ61,P52272,P19338,P98179,Q13242,O75153,O43432,Q14011,P38159,P35637,Q9UIV1,P23588,Q6UN15,O75494,P67809,P61978,O14979,Q9GZT3,Q08170,O43390,Q96E39,Q92804,P51991,Q96PK6,P19474,P31942,P62995,Q96T58,Q99729,Q96SI9,O60506,P52597,Q01844,P22626,Q9NUD5,Q9BWF3,Q8WVV9,Q06787,Q15056,Q07666,Q86U42,Q15477,Q13395,Q96PU8,Q07955,P23246,O75179,Q14103,Q5JTZ9,Q13595,Q96MU7,P09651,Q15637,Q96P11,P31943,Q08J23,Q16629,P07910,Q8WWY3,Q6PJT7,P43243,Q8N684,P51114,O43818,Q71RC2,Q9Y5S9,Q9UJV9,Q9UNQ2,Q9H814,Q96FV9,Q7Z417,Q9Y4C8
Functions
Protein Atlas Molecular function
protein_atlas_molecular_function
1,523,521,517,514,515,548,542,535,532,61,77,78,85,93,109,115,117,120,125,127,129,134,132,146,163,169,173,180,182,188,186,195,197,208,209,212,215,225,226,224,234,239,242,254,255,273,276,302,318,330,324,333,331,335,350,346,368,359,363,382,375,392,407,401,432,428,424,444,439,436,457,465,462,479,478,476,474,527
1380,1046,927,132,1621,969,1575,971,2121,169,85,1993,1382,1793,436,1794,636,215,1995,78,331,127,1125,1384,2165,1086,1469,1162,2428,2167,1527,1010,1,1012,1340,2600,763,1341,2229,401,930,1092,863,1293,359,1167,901,660,1473,1670,933,1344,2499,1054,1345,532,186,1855,2500,1953,224,333,579,120,1298,2092,1392,2432,2557,2265,935,195,375,2096,1300,115,2943,1632,109,2003,2559,1056,424,2006,2458,2061,2179,1254,1480,1590,766,439,686,905,182,535,225,663,2102,1814,1022,1256,514,1141,2377,1358,2010,2301,134,1912,2595,1680,1142,2663,2407,2271,1398,1817,1818,197,1760,129,1720,713,871,515,61,1359,1722,2642,622,1543,226,537,2304,254,273,324,163,1492,714,392,1494,835,1100,1641,1171,2018,563,2380,77,2139,717,1550,1172,318,346,687,1263,1361,93,335,2245,1551,1552,1102,1601,1444,1725,1868,255,584,517,2022,2140,2247,1726,302,1869,363,988,407,1212,1176,874,1404,2275,1727,2024,350,2545,2527,1446,1071,1873,428,1030,125,457,1972,1215,1555,2072,1181,2329,474,1498,2413,276,2703,956,1366,2218,1410,1770,805,2693,2353,444,1687,1219,2251,1976,1185,806,671,1831,521,242,432,722,1078,1225,807,1878,808,180,918,1269,1226,1227,1324,173,1834,1690,1835,476,694,1412,1326,368,382,188,330,1883,212,208,523,2682,2282,209,1651,542,1607,2741,239,1561,2359,2392,146,1154,848,695,651,697,2447,478,1155,2078,1156,627,2474,2493,2285,1930,1931,1702,234,2475,2080,2081,1703,1331,755,1779,2286,921,1704,1656,2420,1002,631,1742,1891,2040,2933,117,462,1333,1894,1236,788,2824,2046,479,548,1937,1844,2478,2422,1570,1571,2048,1239,2895,2697,633,634,2117,527,2812,465,2160,1661
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2,945
Transcription regulation
68
260
2.064496
0.038971
Q96IZ0,Q99459,P67809,Q9H0D6,P61978,Q15233,O14979,Q5QJE6,Q9HCD5,O60885,Q03164,Q8TAQ2,Q9GZT3,Q9UNS1,Q07666,Q8N163,Q8NB78,Q9UBU8,Q99417,Q96I24,O95251,P53999,P49750,Q9BRG1,Q8NEY8,Q6PD62,Q9H1I8,Q92922,Q07021,Q9ULX6,Q9NYF8,Q13547,Q14241,Q96PK6,O00625,P16220,Q9Y6J9,Q15061,Q5BKZ1,Q86YP4,Q9NWT6,Q5VUA4,O60716,P23396,Q9H501,Q9NRL2,Q96T58,P23246,P29692,P61457,Q14103,Q9NX63,Q96FV9,Q8N9N2,Q9UBK9,Q9UPP1,Q01844,P12956,Q9NPA8,Q9UHR5,P13984,P42224,Q96AE4,Q15637,P41223,Q9UIV1,Q9HD42,Q13330
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
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