term
stringlengths
2
121
overlap
int64
6
281
setsize
int64
7
499
score
float64
1.96
10.6
pval
float64
0
0.05
edge
stringlengths
41
1.97k
type
stringclasses
5 values
subtype
stringclasses
24 values
subtype_key
stringclasses
24 values
edge_idxs
stringlengths
11
1.17k
ann_idxs
stringlengths
19
2.31k
ann_vals
stringlengths
124
9.94k
sig_size
int64
2.2k
3.73k
Ion transmembrane transport
38
158
3.224628
0.001261
Q96PU5,Q9H2D1,Q8TB61,Q96ER9,P19174,Q70HW3,Q9UDW1,P46934,Q15043,Q9C0H2,Q9BQT8,P06576,P51790,Q9UHG3,Q7KZN9,Q9HC07,P00403,O75964,P53985,O75027,Q8N4V1,P00846,P45880,Q04656,Q9NW15,Q9Y619,O43772,Q13423,Q9HD20,P30825,Q9UBX3,P08183,P12236,O00400,O60831,P21796,Q8TAD4,O75844
Processes and pathways
GO Biological process
msigdb_gobp
1,4,267,397,264,18,274,20,404,150,23,402,282,40,431,43,174,302,50,425,450,60,71,322,334,81,88,216,94,221,230,107,362,236,365,111,117,121
1693,236,2024,1439,1304,88,441,2500,2391,365,425,2639,2047,1860,888,121,641,1824,302,697,1053,174,60,794,660,749,1307,402,1827,1916,1163,107,809,2107,795,674,1362,1627,1564,362,688,644,2091,264,1112,610,1253,2765,2837,111,1225,980,2377,921,2840,2811,2578,1312,221,1338,538,2353,1397,750,2217,71,20,892,2793,2747,1093,282,1763,1629,50,812,2033,2844,766,648,1029,923,983,1206,2580,2883,836,1507,1171,322,1343,530,1006,2248,1736,216,873,2814,2565,589,2650,404,896,1284,1036,680,490,18,431,601,897,1347,450,1040,117,267,1101,824,397,1269,1579,1155,916,1,2865,1216,2932,2587,23,2785,2847,150,1522,4,1385,804,43,934,94,524,2163,2903,334,230,274,2519,40,2167,1328,734,950,685,654,1689,2445,655,81,2553
-0.24711250387957184,1.3860113542851535,-0.45753228412024466,-0.1001715700836958,-0.010771004982313778,2.2347638458248005,0.8825879960378804,-0.8039006614231072,-0.7199196503135434,1.0105173832723406,0.8969895762705655,-0.9768137628162359,-0.4771701196736191,-0.34151131793657324,0.2967604582024043,1.9624778628651733,0.5686040539973861,-0.3224686466679636,1.1754359209634744,0.5061463962970855,0.16273905820118395,1.6718371053502799,2.530433704556057,0.394648358795702,0.5530732376857973,0.4427821773887004,-0.010771004982313778,0.9399105014520449,-0.3224686466679636,-0.3798459053107705,0.07684293929142288,2.0844088865487853,0.37848518872114384,-0.5167106212981979,0.394648358795702,0.537486950272112,-0.046312846762206455,-0.20991366611478418,-0.17302728582659577,1.0245022054180684,0.5218448013237352,0.5686040539973861,-0.4968959727005952,1.3082387048731943,0.11140380677844741,0.6148675201656797,0.024485024344763594,-1.2029252754937023,-1.4412088289871978,2.0514955668887254,0.04200726311648557,0.21347933237869962,-0.6991718914520957,0.2636380221709174,-1.465757012993624,-1.3683690925791896,-0.8679522324143034,-0.010771004982313778,1.4624128836284802,-0.028505915233174372,0.7209443730522314,-0.6785213070020842,-0.06419237620988717,0.4427821773887004,-0.576695277069889,2.369826344771198,3.178401473028381,0.2967604582024043,-1.2967067971056643,-1.1567689963310013,0.12858251145984356,1.2556043625519968,-0.28462903979626186,-0.20991366611478418,2.7136633954590907,0.37848518872114384,-0.45753228412024466,-1.4904417735103144,0.4267964258326052,0.5686040539973861,0.17971792076718154,0.2636380221709174,0.21347933237869962,0.05945972020734923,-0.8679522324143034,-1.7451438249828646,0.3459784040561311,-0.1364482501831472,0.07684293929142288,1.1347895625307758,-0.028505915233174372,0.7358896549563253,0.1966311801772001,-0.596873097659703,-0.26583072691689574,1.4875835034045466,0.31322807591179413,-1.3683690925791896,-0.8464982748968118,0.660645419060983,-0.9768137628162359,0.9399105014520449,0.2967604582024043,0.00689245382919885,0.17971792076718154,0.537486950272112,0.8098565473687283,3.2289128066153725,0.8969895762705655,0.6301802761408241,0.2967604582024043,-0.028505915233174372,0.8825879960378804,0.17971792076718154,1.9960752529228047,1.3082387048731943,0.12858251145984356,0.36226201680927644,0.954123884167548,0.024485024344763594,-0.17302728582659577,0.09415745775210213,0.2802305948711232,3.8435086970139305,-1.5905769604580335,0.05945972020734923,-3.2232065341232468,-0.8679522324143034,3.118706149066854,-1.2495678211004613,-1.5152646108352479,1.8137877280347836,-0.1364482501831472,3.666003780285035,-0.046312846762206455,0.394648358795702,2.8712191617408704,0.2636380221709174,2.1816663680647275,0.7507838500099976,-0.5366148538627052,-1.9052771337681562,1.121155788951183,1.4243805350193866,1.2820013709130165,-0.8039006614231072,2.8893796757735113,-0.5366148538627052,-0.010771004982313778,0.4745792189320432,0.24698227118508845,0.537486950272112,0.5686040539973861,-0.22847370331607397,-0.7407654856874151,0.5686040539973861,2.3183799967279364,-0.825148078218146
2,948
Negative regulation of rna catabolic process
14
32
3.216937
0.001296
P35637,Q14011,Q13151,O60506,P49137,P67809,Q92804,Q9H074,Q06787,Q14103,P07910,Q99729,P98175,Q08J23
Processes and pathways
GO Biological process
msigdb_gobp
98,99,356,135,265,171,204,434,530,245,527,154,382,222
1133,135,1938,1464,1724,527,719,98,1313,265,171,382,1675,530,1598,222,2561,356,99,245,986,926,1037,2260,204,154,558,434,1648,1240,1049,1020
0.09415745775210213,1.894487649782089,-0.3991392521076305,-0.11827242278503895,-0.26583072691689574,0.7358896549563253,0.4745792189320432,2.1279058027565836,-0.010771004982313778,1.3082387048731943,1.6838460454736341,0.9824120538036047,-0.22847370331607397,0.7358896549563253,-0.19143174128541807,1.4624128836284802,-0.8464982748968118,1.0384421790618117,2.1279058027565836,1.373145758933382,0.21347933237869962,0.2636380221709174,0.17971792076718154,-0.596873097659703,1.537489972244893,1.7787349139536996,0.7059476590359905,0.8969895762705655,-0.20991366611478418,0.04200726311648557,0.17971792076718154,0.1966311801772001
2,948
Organophosphate ester transport
8
22
3.212432
0.001316
Q14108,Q8WTV0,Q9H2D1,Q8TB61,P08183,P12236,O00400,Q08722
Processes and pathways
GO Biological process
msigdb_gobp
162,68,4,267,107,362,236,275
236,441,749,107,1564,362,1470,1664,1503,1768,1207,275,162,1036,927,1423,267,68,1579,991,4,934
1.3860113542851535,0.8825879960378804,0.4427821773887004,2.0844088865487853,-0.17302728582659577,1.0245022054180684,-0.11827242278503895,-0.22847370331607397,-0.1364482501831472,-0.28462903979626186,0.05945972020734923,1.2688229452074793,1.7315509278111096,0.17971792076718154,0.2636380221709174,-0.08214508712671734,1.3082387048731943,2.4206641920055536,-0.17302728582659577,0.21347933237869962,3.666003780285035,0.2636380221709174
2,948
Intrinsic component of mitochondrial membrane
30
47
3.203259
0.001359
Q9Y4W6,Q9Y512,Q16134,Q96ER9,Q96NB2,O75880,Q9H9B4,Q6UXV4,Q9NVH1,Q9HC21,O43819,Q6P4A7,Q9H9P8,Q99595,Q9NX63,Q9Y2R0,O14925,Q96AQ8,O95140,Q16891,Q9BUR5,Q9UG56,Q15070,Q00325,O75431,Q9H3K2,Q5XKP0,P50416,O60830,Q13505
Localization
GO Cellular component
msigdb_gocc
655,260,262,397,916,640,804,666,549,934,792,680,169,42,436,300,552,824,426,564,183,706,323,836,338,730,860,722,106,244
552,792,106,338,640,1443,426,2238,1564,2508,722,922,836,244,323,1082,262,564,1839,1231,860,680,666,1711,1424,1040,1457,824,397,916,42,2587,1322,183,730,804,169,934,1931,549,436,706,1243,300,655,260,1437
0.7059476590359905,0.394648358795702,2.0844088865487853,1.0937591810735925,0.5686040539973861,-0.1001715700836958,0.8969895762705655,-0.596873097659703,-0.17302728582659577,-0.8039006614231072,0.4745792189320432,0.2636380221709174,0.3459784040561311,1.373145758933382,1.1347895625307758,0.1456940908786263,1.3212980845713802,0.6908991641556643,-0.3224686466679636,0.04200726311648557,0.3296339066521189,0.537486950272112,0.5530732376857973,-0.24711250387957184,-0.08214508712671734,0.17971792076718154,-0.1001715700836958,0.36226201680927644,0.954123884167548,0.2802305948711232,2.8712191617408704,-0.8679522324143034,-0.010771004982313778,1.6477186929262733,0.4745792189320432,0.394648358795702,1.6958217180030357,0.2636380221709174,-0.3798459053107705,0.7209443730522314,0.8969895762705655,0.5061463962970855,0.04200726311648557,1.188900583250081,0.5686040539973861,1.3343182502559603,-0.08214508712671734
2,948
Peptide binding
12
71
3.194201
0.001402
Q15392,P55786,Q9Y584,Q8WTV0,Q9NZ08,Q9NQX7,Q9UIQ6,P24390,P42892,O43731,P55899,O00264
Functions
GO Molecular function
msigdb_gomf
33,2,133,68,105,142,12,15,16,19,115,92
774,92,789,1993,657,1858,608,1619,2499,19,2638,1443,339,348,1726,869,475,977,1395,2881,2822,15,2280,2811,2578,1567,1228,2282,427,16,2885,2056,2662,1367,503,2429,1542,2,115,2302,923,1767,1143,676,2307,2564,1081,2463,1082,33,2095,637,68,455,1682,1268,989,898,2441,186,1714,578,142,1583,105,1788,437,12,1490,1131,133
0.4107519613001489,2.1816663680647275,0.394648358795702,-0.43798169806465925,0.5530732376857973,-0.34151131793657324,0.6148675201656797,-0.20991366611478418,-0.8039006614231072,3.1953050908815848,-0.9768137628162359,-0.1001715700836958,1.0937591810735925,1.06618870455087,-0.26583072691689574,0.31322807591179413,0.8245003681365923,0.21347933237869962,-0.06419237620988717,-1.7190065204560596,-1.392516309666817,3.2622578968216644,-0.6171437624952562,-1.3683690925791896,-0.8679522324143034,-0.17302728582659577,0.04200726311648557,-0.6171437624952562,0.8969895762705655,3.245617927748801,-1.77143566283669,-0.4771701196736191,-0.9989116898321668,-0.046312846762206455,0.7804203434389911,-0.7407654856874151,-0.154699664595971,3.711080088907221,2.007216460441714,-0.6375081142813843,0.2636380221709174,-0.28462903979626186,0.09415745775210213,0.537486950272112,-0.6375081142813843,-0.8464982748968118,0.1456940908786263,-0.7617103122164987,0.1456940908786263,2.9967531033007075,-0.4968959727005952,0.5840797855852801,2.4206641920055536,0.8681385994260129,-0.22847370331607397,0.024485024344763594,0.21347933237869962,0.2967604582024043,-0.7407654856874151,1.6356088521917012,-0.24711250387957184,0.6757985361220961,1.8715840661178529,-0.17302728582659577,2.095324359314597,-0.28462903979626186,0.8969895762705655,3.368863420764839,-0.11827242278503895,0.11140380677844741,1.917270315417413
2,948
Molecular transducer activity
15
29
3.189938
0.001423
P11717,O15118,Q14108,Q8WTV0,Q9UGP8,Q9UKV5,Q99720,O15173,Q15629,Q9BUN8,Q4VCS5,Q08722,Q99523,Q5KU26,P10586
Functions
GO Molecular function
msigdb_gomf
350,129,162,68,168,299,467,80,148,53,565,275,213,349,253
129,80,2319,1307,253,350,2900,1502,1398,1365,2721,275,1401,162,562,148,1284,565,349,68,1101,1606,213,467,53,1386,1855,168,299
1.917270315417413,2.3183799967279364,-0.6579670071768167,-0.010771004982313778,1.3472994325027918,1.0523375857873305,-1.8781849174669127,-0.1364482501831472,-0.06419237620988717,-0.046312846762206455,-1.0884248463707054,1.2688229452074793,-0.06419237620988717,1.7315509278111096,0.6908991641556643,1.8137877280347836,0.00689245382919885,0.6908991641556643,1.06618870455087,2.4206641920055536,0.12858251145984356,-0.19143174128541807,1.5126086522989541,0.8390951028692502,2.6852478237468818,-0.046312846762206455,-0.3224686466679636,1.7077643034433876,1.188900583250081
2,948
Protein transmembrane transport
8
24
3.160579
0.001575
Q9Y584,Q9NS69,Q9UGP8,Q99595,O60830,Q15629,O95831,O75298
Processes and pathways
GO Biological process
msigdb_gobp
133,7,168,42,106,148,57,95
552,791,106,95,1191,1443,57,2238,2527,194,554,2537,2302,923,2772,1082,148,947,1606,42,1354,7,168,133
0.7059476590359905,0.394648358795702,2.0844088865487853,2.170967820101334,0.05945972020734923,-0.1001715700836958,2.6085391476555078,-0.596873097659703,-0.825148078218146,1.5868275562513716,0.7059476590359905,-0.825148078218146,-0.6375081142813843,0.2636380221709174,-1.2261851370906078,0.1456940908786263,1.8137877280347836,0.24698227118508845,-0.19143174128541807,2.8712191617408704,-0.028505915233174372,3.496511927362126,1.7077643034433876,1.917270315417413
2,948
Mental deterioration
33
94
3.156427
0.001597
O15118,P31483,P50897,P03886,Q06787,Q9BQE5,O43464,P21964,O75503,Q14108,P35670,P04350,Q6PI48,P09651,Q03164,P00403,P27544,O95140,O76024,P00846,Q10713,Q9NQZ5,P43243,O60220,P54802,O95470,O60313,Q9Y487,P35637,P22626,P07602,Q9NPL8,Q9NZJ7
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
129,392,144,145,530,25,400,287,32,162,538,537,164,294,173,174,303,426,313,60,447,64,452,337,83,214,460,89,98,227,110,505,517
628,129,400,1073,792,337,460,1334,2478,1968,32,313,426,214,2238,174,60,145,707,2821,537,998,110,2780,2526,1625,294,2641,687,978,2576,979,630,1113,870,287,227,2614,303,1889,392,98,538,750,2217,1313,452,1203,144,2510,1920,83,1894,1733,1768,800,2058,173,1705,2306,530,447,2561,1033,162,985,2308,1375,860,1900,164,1064,2010,1084,1552,2368,567,1380,1713,2865,2789,25,1555,505,64,2919,2198,517,1185,1932,2345,1018,1490,89
0.5840797855852801,1.917270315417413,0.9399105014520449,0.1456940908786263,0.394648358795702,1.0937591810735925,0.8390951028692502,-0.028505915233174372,-0.7827550573182713,-0.41851760347793965,3.040708346375522,1.1483806684923388,0.8969895762705655,1.5001141584399327,-0.596873097659703,1.6718371053502799,2.530433704556057,1.8369991927238165,0.4903913364797827,-1.392516309666817,0.7209443730522314,0.1966311801772001,2.06249462948218,-1.2495678211004613,-0.825148078218146,-0.20991366611478418,1.202323609529759,-0.9768137628162359,0.5218448013237352,0.21347933237869962,-0.8679522324143034,0.21347933237869962,0.5840797855852801,0.11140380677844741,0.31322807591179413,1.2423453819314823,1.4243805350193866,-0.9329466915129715,1.1754359209634744,-0.36063683389058815,0.954123884167548,2.1279058027565836,0.7209443730522314,0.4427821773887004,-0.576695277069889,-0.010771004982313778,0.8681385994260129,0.05945972020734923,1.8485582976056778,-0.8039006614231072,-0.3798459053107705,2.2767750906766135,-0.36063683389058815,-0.26583072691689574,-0.28462903979626186,0.394648358795702,-0.4771701196736191,1.6838460454736341,-0.24711250387957184,-0.6375081142813843,0.7358896549563253,0.8825879960378804,-0.8464982748968118,0.17971792076718154,1.7315509278111096,0.21347933237869962,-0.6375081142813843,-0.046312846762206455,0.3296339066521189,-0.36063683389058815,1.7196739808433925,0.16273905820118395,-0.43798169806465925,0.1456940908786263,-0.154699664595971,-0.6785213070020842,0.6908991641556643,-0.046312846762206455,-0.24711250387957184,-1.5905769604580335,-1.2730746077112312,3.1014959487367078,-0.154699664595971,0.7804203434389911,2.4508806535723897,-2.332755838948225,-0.5566094692716574,0.7656273000310847,0.07684293929142288,-0.3798459053107705,-0.6579670071768167,0.1966311801772001,-0.11827242278503895,2.2347638458248005
2,948
Inner mitochondrial membrane organization
18
25
3.145707
0.001657
Q9Y4W6,Q9Y584,Q9Y512,Q9Y5J7,Q96E52,Q9NX63,Q9P0J0,Q9Y5J9,P62072,O60220,O75431,Q13505,Q6UXV4,Q16891,O60313,Q9NVH1,Q9BUR5,O95202
Processes and pathways
GO Biological process
msigdb_gobp
655,133,260,199,229,436,176,336,664,337,338,244,666,564,460,549,183,697
337,460,338,1443,697,2508,664,244,564,1839,1231,860,666,229,183,730,549,436,176,655,260,133,199,336,906
1.0937591810735925,0.8390951028692502,1.0937591810735925,-0.1001715700836958,0.5061463962970855,-0.8039006614231072,0.5530732376857973,1.373145758933382,0.6908991641556643,-0.3224686466679636,0.04200726311648557,0.3296339066521189,0.5530732376857973,1.4243805350193866,1.6477186929262733,0.4745792189320432,0.7209443730522314,0.8969895762705655,1.6718371053502799,0.5686040539973861,1.3343182502559603,1.917270315417413,1.574545797147203,1.1074790838974617,0.2967604582024043
2,948
SLC25 family of mitochondrial transporters
8
20
3.145286
0.001659
Q9H2D1,Q9UBX3,P12236,Q9Y619,Q70HW3,Q9BQT8,O43772,O43808
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
4,230,362,81,18,23,88,441
88,441,888,749,1564,362,1629,836,1171,927,18,23,4,1385,934,517,230,1328,81,975
2.2347638458248005,0.8825879960378804,0.2967604582024043,0.4427821773887004,-0.17302728582659577,1.0245022054180684,-0.20991366611478418,0.3459784040561311,0.07684293929142288,0.2636380221709174,3.2289128066153725,3.118706149066854,3.666003780285035,-0.046312846762206455,0.2636380221709174,0.7656273000310847,1.4243805350193866,-0.010771004982313778,2.3183799967279364,0.23026286775039087
2,948
Mitochondrial substrate/solute carrier [IPR018108]
8
20
3.145286
0.001659
Q9H2D1,Q9UBX3,P12236,Q9Y619,Q70HW3,Q9BQT8,O43772,O43808
Sequence
InterPro Repeat
interpro_repeat
4,230,362,81,18,23,88,441
88,441,888,749,1564,362,1629,836,1171,927,18,23,4,1385,934,517,230,1328,81,975
2.2347638458248005,0.8825879960378804,0.2967604582024043,0.4427821773887004,-0.17302728582659577,1.0245022054180684,-0.20991366611478418,0.3459784040561311,0.07684293929142288,0.2636380221709174,3.2289128066153725,3.118706149066854,3.666003780285035,-0.046312846762206455,0.2636380221709174,0.7656273000310847,1.4243805350193866,-0.010771004982313778,2.3183799967279364,0.23026286775039087
2,948
Mitochondrial carrier domain superfamily [IPR023395]
8
20
3.145286
0.001659
Q9H2D1,Q9UBX3,P12236,Q9Y619,Q70HW3,Q9BQT8,O43772,O43808
Sequence
InterPro Superfamily
interpro_homologous_superfamily
4,230,362,81,18,23,88,441
88,441,888,749,1564,362,1629,836,1171,927,18,23,4,1385,934,517,230,1328,81,975
2.2347638458248005,0.8825879960378804,0.2967604582024043,0.4427821773887004,-0.17302728582659577,1.0245022054180684,-0.20991366611478418,0.3459784040561311,0.07684293929142288,0.2636380221709174,3.2289128066153725,3.118706149066854,3.666003780285035,-0.046312846762206455,0.2636380221709174,0.7656273000310847,1.4243805350193866,-0.010771004982313778,2.3183799967279364,0.23026286775039087
2,948
Tetratricopeptide-like helical domain superfamily [IPR011990]
25
81
3.129498
0.001751
O00411,O75153,O75718,Q6DKK2,O43242,O15460,Q13042,Q9H270,Q9Y262,Q6ZXV5,Q15006,Q9Y5A7,Q92791,Q9BXJ9,P13674,O76024,Q9NSK0,Q32P28,A0AVF1,Q96BR5,P49321,Q96EK5,Q96DB5,Q14CX7,Q6PGP7
Sequence
InterPro Superfamily
interpro_homologous_superfamily
378,6,21,152,399,398,412,415,416,540,539,438,44,311,55,313,320,198,196,465,462,343,480,235,383
196,850,656,378,1189,919,1440,398,399,1936,6,21,313,2601,1443,2524,1415,55,1226,1890,1536,1027,1313,462,1367,2401,1867,1506,2058,1314,925,2307,724,2355,412,1032,912,2155,2512,235,539,1147,1773,1898,198,700,152,862,383,540,2366,1409,44,465,480,343,1212,931,1746,1811,881,311,2754,626,415,1351,2549,1384,1107,1609,320,759,716,1087,579,2345,416,2102,2347,438,1160
1.574545797147203,0.3296339066521189,0.5530732376857973,0.9824120538036047,0.05945972020734923,0.2636380221709174,-0.1001715700836958,0.9399105014520449,0.9399105014520449,-0.3991392521076305,3.558929341369213,3.1529198842609487,1.1483806684923388,-0.9111754241704362,-0.1001715700836958,-0.825148078218146,-0.08214508712671734,2.627845336521186,0.04200726311648557,-0.36063683389058815,-0.154699664595971,0.17971792076718154,-0.010771004982313778,0.8390951028692502,-0.046312846762206455,-0.7199196503135434,-0.34151131793657324,-0.1364482501831472,-0.4771701196736191,-0.010771004982313778,0.2636380221709174,-0.6375081142813843,0.4745792189320432,-0.6785213070020842,0.925650523668678,0.17971792076718154,0.2802305948711232,-0.5366148538627052,-0.8039006614231072,1.3988388685809194,0.7209443730522314,0.09415745775210213,-0.28462903979626186,-0.36063683389058815,1.574545797147203,0.5061463962970855,1.8021350389030668,0.3296339066521189,0.9824120538036047,0.7209443730522314,-0.6785213070020842,-0.06419237620988717,2.8529812632786027,0.8390951028692502,0.8245003681365923,1.0937591810735925,0.05945972020734923,0.2636380221709174,-0.26583072691689574,-0.3035081182804855,0.31322807591179413,1.161929368281666,-1.1567689963310013,0.5995008148293052,0.925650523668678,-0.028505915233174372,-0.825148078218146,-0.046312846762206455,0.12858251145984356,-0.19143174128541807,1.1483806684923388,0.4427821773887004,0.4903913364797827,0.1456940908786263,0.6757985361220961,-0.6579670071768167,0.925650523668678,-0.4968959727005952,-0.6579670071768167,0.8969895762705655,0.09415745775210213
2,948
Cognitive impairment
46
153
3.128458
0.001757
O15118,P31483,P50897,P03886,Q06787,Q6DKK2,Q9BQE5,O43464,P21964,O75503,Q14108,P35670,P04350,Q6PI48,P09651,O75569,Q9Y2R0,Q03164,P00403,P27544,P40855,O95140,O95831,O76024,P00846,Q10713,Q9NQZ5,P43243,Q9NR50,Q99720,Q9Y619,O60220,P54802,P01889,O95470,O60313,Q9Y487,P35637,P22626,Q9Y263,Q9NZ08,P07602,Q8N0X7,Q9NPL8,Q6PGP7,Q9NZJ7
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
129,392,144,145,530,152,25,400,287,32,162,538,537,164,294,170,300,173,174,303,427,426,57,313,60,447,64,452,457,467,81,337,83,339,214,460,89,98,227,359,105,110,368,505,383,517
628,696,129,400,1073,792,337,460,1334,2478,1968,2447,1191,32,170,313,426,214,57,2238,174,60,339,145,707,2821,537,2376,708,998,110,2780,2713,2526,1625,294,2641,687,1564,978,2576,979,630,1113,2837,1396,870,287,2737,227,2614,303,1889,392,1590,98,538,750,2217,427,1027,1313,452,1200,2858,1365,1203,1366,144,2510,1920,1260,1570,83,1894,1733,1141,2285,923,1768,800,2058,924,1004,173,1705,2306,530,447,1546,2561,1032,1033,162,985,1405,2062,2795,2308,2408,632,1375,2904,860,152,1900,383,164,1064,368,2010,1084,1267,1552,2368,704,1102,567,1380,1713,2865,2789,467,25,1239,1555,2632,1815,505,2877,64,457,1784,2919,2198,105,517,1185,1932,1130,669,1328,807,2345,1187,1018,359,1490,300,89,655,1819,81
0.5840797855852801,0.5061463962970855,1.917270315417413,0.9399105014520449,0.1456940908786263,0.394648358795702,1.0937591810735925,0.8390951028692502,-0.028505915233174372,-0.7827550573182713,-0.41851760347793965,-0.7617103122164987,0.05945972020734923,3.040708346375522,1.6838460454736341,1.1483806684923388,0.8969895762705655,1.5001141584399327,2.6085391476555078,-0.596873097659703,1.6718371053502799,2.530433704556057,1.0937591810735925,1.8369991927238165,0.4903913364797827,-1.392516309666817,0.7209443730522314,-0.6991718914520957,0.4903913364797827,0.1966311801772001,2.06249462948218,-1.2495678211004613,-1.0884248463707054,-0.825148078218146,-0.20991366611478418,1.202323609529759,-0.9768137628162359,0.5218448013237352,-0.17302728582659577,0.21347933237869962,-0.8679522324143034,0.21347933237869962,0.5840797855852801,0.11140380677844741,-1.4412088289871978,-0.06419237620988717,0.31322807591179413,1.2423453819314823,-1.133870114754212,1.4243805350193866,-0.9329466915129715,1.1754359209634744,-0.36063683389058815,0.954123884167548,-0.19143174128541807,2.1279058027565836,0.7209443730522314,0.4427821773887004,-0.576695277069889,0.8969895762705655,0.17971792076718154,-0.010771004982313778,0.8681385994260129,0.05945972020734923,-1.5653306411594137,-0.046312846762206455,0.05945972020734923,-0.046312846762206455,1.8485582976056778,-0.8039006614231072,-0.3798459053107705,0.024485024344763594,-0.17302728582659577,2.2767750906766135,-0.36063683389058815,-0.26583072691689574,0.09415745775210213,-0.6171437624952562,0.2636380221709174,-0.28462903979626186,0.394648358795702,-0.4771701196736191,0.2636380221709174,0.1966311801772001,1.6838460454736341,-0.24711250387957184,-0.6375081142813843,0.7358896549563253,0.8825879960378804,-0.154699664595971,-0.8464982748968118,0.17971792076718154,0.17971792076718154,1.7315509278111096,0.21347933237869962,-0.06419237620988717,-0.4771701196736191,-1.2967067971056643,-0.6375081142813843,-0.7199196503135434,0.5840797855852801,-0.046312846762206455,-1.9325351999326172,0.3296339066521189,1.8021350389030668,-0.36063683389058815,0.9824120538036047,1.7196739808433925,0.16273905820118395,1.0105173832723406,-0.43798169806465925,0.1456940908786263,0.024485024344763594,-0.154699664595971,-0.6785213070020842,0.5061463962970855,0.12858251145984356,0.6908991641556643,-0.046312846762206455,-0.24711250387957184,-1.5905769604580335,-1.2730746077112312,0.8390951028692502,3.1014959487367078,0.04200726311648557,-0.154699664595971,-0.9548257864570027,-0.3035081182804855,0.7804203434389911,-1.6671884467700155,2.4508806535723897,0.8681385994260129,-0.28462903979626186,-2.332755838948225,-0.5566094692716574,2.095324359314597,0.7656273000310847,0.07684293929142288,-0.3798459053107705,0.11140380677844741,0.5530732376857973,-0.010771004982313778,0.394648358795702,-0.6579670071768167,0.07684293929142288,0.1966311801772001,1.0384421790618117,-0.11827242278503895,1.188900583250081,2.2347638458248005,0.5686040539973861,-0.3035081182804855,2.3183799967279364
2,948
Serine hydrolase activity
10
20
3.095051
0.001968
Q9H300,P42785,Q16740,Q9HB40,Q4J6C6,O75976,O43464,Q5JRX3,Q9H3G5,P53634
Functions
GO Molecular function
msigdb_gomf
325,5,136,141,82,120,400,59,188,445
657,400,120,476,1565,1501,1256,5,1700,1542,445,784,136,82,59,2122,2437,325,188,141
0.5530732376857973,0.9399105014520449,1.9737061019075504,0.8245003681365923,-0.17302728582659577,-0.1364482501831472,0.024485024344763594,3.574391697694004,-0.24711250387957184,-0.154699664595971,0.8825879960378804,0.4107519613001489,1.8830510514184668,2.2976278530369267,2.5794159618228156,-0.5167106212981979,-0.7407654856874151,1.1347895625307758,1.6234650069627081,1.8715840661178529
2,948
Abnormal heart valve morphology
28
73
3.090956
0.001995
Q96PU5,Q12768,P61978,P55795,Q06787,P21964,Q6ZXV5,Q15056,Q15233,O95155,Q06330,P10644,Q15477,O00571,Q9UHX1,O95202,Q5H8A4,P06280,O96028,O75431,Q14697,P01889,P53701,P37268,Q8NCH0,P06753,O75844,Q6PGP7
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
1,649,139,269,530,287,540,422,165,673,47,687,563,694,61,697,195,708,335,338,595,339,478,223,113,618,121,383
694,2138,1440,1528,2683,1441,338,121,673,697,335,339,1249,707,708,618,889,1563,687,978,2837,1396,287,1532,2028,1534,2054,1279,750,223,2730,2001,1763,1095,478,2032,1894,269,1702,139,1672,2003,1949,924,1735,1372,2771,47,530,649,2563,595,1061,422,165,563,195,1738,927,383,540,113,1983,1,1215,1322,1747,2233,1068,61,2133,1187,2270
0.5061463962970855,-0.5366148538627052,-0.1001715700836958,-0.154699664595971,-1.0434417517569528,-0.1001715700836958,1.0937591810735925,1.9624778628651733,0.537486950272112,0.5061463962970855,1.1074790838974617,1.0937591810735925,0.024485024344763594,0.4903913364797827,0.4903913364797827,0.5995008148293052,0.2967604582024043,-0.17302728582659577,0.5218448013237352,0.21347933237869962,-1.4412088289871978,-0.06419237620988717,1.2423453819314823,-0.154699664595971,-0.45753228412024466,-0.154699664595971,-0.4771701196736191,0.00689245382919885,0.4427821773887004,1.449772501389248,-1.1110891268052037,-0.43798169806465925,-0.28462903979626186,0.12858251145984356,0.8245003681365923,-0.45753228412024466,-0.36063683389058815,1.2951398785464203,-0.24711250387957184,1.8715840661178529,-0.22847370331607397,-0.43798169806465925,-0.3991392521076305,0.2636380221709174,-0.26583072691689574,-0.046312846762206455,-1.2261851370906078,2.769935459729976,0.7358896549563253,0.5686040539973861,-0.8464982748968118,0.6454394534643092,0.16273905820118395,0.9113436498871638,1.7077643034433876,0.6908991641556643,1.5868275562513716,-0.26583072691689574,0.2636380221709174,0.9824120538036047,0.7209443730522314,2.0294128700184095,-0.41851760347793965,3.8435086970139305,0.05945972020734923,-0.010771004982313778,-0.26583072691689574,-0.576695277069889,0.16273905820118395,2.530433704556057,-0.5167106212981979,0.07684293929142288,-0.596873097659703
2,948
Ion transport
69
205
3.089714
0.002003
Q9Y4W6,Q96PU5,Q9Y277,Q9H2D1,P56385,Q9HD26,Q8TB61,P16615,P14174,P19174,O75915,Q96ER9,Q70HW3,Q9UKS6,P46934,Q06787,Q9C0H2,Q9BQT8,Q9UDW1,Q08722,P51790,P05026,Q15043,Q96S66,P06576,Q9UMX0,P35670,Q6P4A7,Q9UHG3,Q7KZN9,Q9HC07,P00403,O75964,P53985,O75027,O76024,P54105,Q8N4V1,P00846,O43808,P02786,P45880,Q14847,Q04656,Q9NW15,O15173,Q9Y619,O43772,Q13423,Q8IUH4,Q9HD20,P30825,Q13555,P20674,Q9UBX3,Q9NY64,Q6P4Q7,P08183,P12236,Q96EV8,O00400,P07602,P21796,O60831,Q96QD8,Q8TAD4,O75844,O00429,Q9NZJ7
Processes and pathways
GO Biological process
msigdb_gobp
655,1,654,4,648,524,267,644,643,264,641,397,18,670,20,530,150,23,274,275,282,660,404,545,402,685,538,680,40,431,43,174,302,50,425,313,561,450,60,441,442,71,589,322,334,80,81,88,216,601,94,221,249,610,230,408,490,107,362,624,236,110,111,365,118,117,121,628,517
2860,1693,236,628,2024,1439,2928,762,80,1073,1304,88,441,2500,2391,365,425,2639,2047,1886,1860,888,121,641,1824,302,313,697,1053,2238,174,60,442,1223,794,660,749,1307,402,1827,1916,110,1163,107,809,2107,795,674,1362,2528,1627,1564,362,688,1468,643,644,2091,264,1112,1337,610,1253,2765,2837,1396,111,1532,1225,980,721,2377,921,2840,2811,1139,2578,2900,1312,221,1338,1166,1759,538,2353,1397,750,2217,71,2701,20,892,2793,2747,1093,282,1763,723,1629,50,561,812,2033,2844,766,648,1506,1029,2329,923,983,1206,2580,2883,836,1507,2058,1314,1171,322,1343,530,1006,275,2248,1736,216,873,249,2814,2565,589,2650,1122,404,896,1284,2289,1036,2666,927,1923,680,490,18,431,601,897,1347,450,864,1040,117,267,1101,824,397,1269,624,1579,1155,916,1,118,545,2865,1216,2932,2587,23,2785,2847,150,1522,4,917,1385,804,43,934,94,524,2163,2903,334,408,517,230,274,2519,40,2167,1328,734,670,950,685,2590,1298,654,1689,2445,655,81,2553
-1.5905769604580335,-0.24711250387957184,1.3860113542851535,0.5840797855852801,-0.45753228412024466,-0.1001715700836958,-2.8388595641615995,0.4267964258326052,2.3183799967279364,0.1456940908786263,-0.010771004982313778,2.2347638458248005,0.8825879960378804,-0.8039006614231072,-0.7199196503135434,1.0105173832723406,0.8969895762705655,-0.9768137628162359,-0.4771701196736191,-0.36063683389058815,-0.34151131793657324,0.2967604582024043,1.9624778628651733,0.5686040539973861,-0.3224686466679636,1.1754359209634744,1.1483806684923388,0.5061463962970855,0.16273905820118395,-0.596873097659703,1.6718371053502799,2.530433704556057,0.8825879960378804,0.04200726311648557,0.394648358795702,0.5530732376857973,0.4427821773887004,-0.010771004982313778,0.9399105014520449,-0.3224686466679636,-0.3798459053107705,2.06249462948218,0.07684293929142288,2.0844088865487853,0.37848518872114384,-0.5167106212981979,0.394648358795702,0.537486950272112,-0.046312846762206455,-0.825148078218146,-0.20991366611478418,-0.17302728582659577,1.0245022054180684,0.5218448013237352,-0.11827242278503895,0.5686040539973861,0.5686040539973861,-0.4968959727005952,1.3082387048731943,0.11140380677844741,-0.028505915233174372,0.6148675201656797,0.024485024344763594,-1.2029252754937023,-1.4412088289871978,-0.06419237620988717,2.0514955668887254,-0.154699664595971,0.04200726311648557,0.21347933237869962,0.4745792189320432,-0.6991718914520957,0.2636380221709174,-1.465757012993624,-1.3683690925791896,0.09415745775210213,-0.8679522324143034,-1.8781849174669127,-0.010771004982313778,1.4624128836284802,-0.028505915233174372,0.07684293929142288,-0.28462903979626186,0.7209443730522314,-0.6785213070020842,-0.06419237620988717,0.4427821773887004,-0.576695277069889,2.369826344771198,-1.065876105040331,3.178401473028381,0.2967604582024043,-1.2967067971056643,-1.1567689963310013,0.12858251145984356,1.2556043625519968,-0.28462903979626186,0.4745792189320432,-0.20991366611478418,2.7136633954590907,0.6908991641556643,0.37848518872114384,-0.45753228412024466,-1.4904417735103144,0.4267964258326052,0.5686040539973861,-0.1364482501831472,0.17971792076718154,-0.6579670071768167,0.2636380221709174,0.21347933237869962,0.05945972020734923,-0.8679522324143034,-1.7451438249828646,0.3459784040561311,-0.1364482501831472,-0.4771701196736191,-0.010771004982313778,0.07684293929142288,1.1347895625307758,-0.028505915233174372,0.7358896549563253,0.1966311801772001,1.2688229452074793,-0.596873097659703,-0.26583072691689574,1.4875835034045466,0.31322807591179413,1.3602418598724249,-1.3683690925791896,-0.8464982748968118,0.660645419060983,-0.9768137628162359,0.11140380677844741,0.9399105014520449,0.2967604582024043,0.00689245382919885,-0.6171437624952562,0.17971792076718154,-0.9989116898321668,0.2636380221709174,-0.3798459053107705,0.537486950272112,0.8098565473687283,3.2289128066153725,0.8969895762705655,0.6301802761408241,0.2967604582024043,-0.028505915233174372,0.8825879960378804,0.3296339066521189,0.17971792076718154,1.9960752529228047,1.3082387048731943,0.12858251145984356,0.36226201680927644,0.954123884167548,0.024485024344763594,0.5995008148293052,-0.17302728582659577,0.09415745775210213,0.2802305948711232,3.8435086970139305,1.9960752529228047,0.7209443730522314,-1.5905769604580335,0.05945972020734923,-3.2232065341232468,-0.8679522324143034,3.118706149066854,-1.2495678211004613,-1.5152646108352479,1.8137877280347836,-0.1364482501831472,3.666003780285035,0.2802305948711232,-0.046312846762206455,0.394648358795702,2.8712191617408704,0.2636380221709174,2.1816663680647275,0.7507838500099976,-0.5366148538627052,-1.9052771337681562,1.121155788951183,0.9399105014520449,0.7656273000310847,1.4243805350193866,1.2820013709130165,-0.8039006614231072,2.8893796757735113,-0.5366148538627052,-0.010771004982313778,0.4745792189320432,0.5530732376857973,0.24698227118508845,0.537486950272112,-0.8679522324143034,0.00689245382919885,0.5686040539973861,-0.22847370331607397,-0.7407654856874151,0.5686040539973861,2.3183799967279364,-0.825148078218146
2,948
Exopeptidase activity
16
32
3.079801
0.002071
P02786,P10619,P55786,Q9NQH7,P42785,Q7Z2K6,Q9NZ08,Q9HB40,Q9UIQ6,Q8IYS1,P09960,P50579,O75976,O75844,Q9H3G5,P53634
Functions
GO Molecular function
msigdb_gomf
442,476,2,326,5,432,105,141,12,496,51,22,120,121,188,445
657,121,120,442,51,476,2716,2766,1501,612,5,22,445,2,2825,2357,2095,432,2437,496,1845,515,1984,2548,188,1324,141,326,1557,1558,105,12
0.5530732376857973,1.9624778628651733,1.9737061019075504,0.8825879960378804,2.694740627138941,0.8245003681365923,-1.0884248463707054,-1.2029252754937023,-0.1364482501831472,0.6148675201656797,3.574391697694004,3.127285314223585,0.8825879960378804,3.711080088907221,-1.392516309666817,-0.6785213070020842,-0.4968959727005952,0.8969895762705655,-0.7407654856874151,0.7951633152994793,-0.3224686466679636,0.7656273000310847,-0.41851760347793965,-0.825148078218146,1.6234650069627081,-0.010771004982313778,1.8715840661178529,1.1347895625307758,-0.154699664595971,-0.154699664595971,2.095324359314597,3.368863420764839
2,948
Negative regulation of mrna catabolic process
12
25
3.039866
0.002367
P35637,Q14011,Q13151,O60506,P49137,P67809,Q92804,Q9H074,Q06787,Q14103,Q99729,P98175
Processes and pathways
GO Biological process
msigdb_gobp
98,99,356,135,265,171,204,434,530,245,154,382
1133,135,1464,527,719,98,265,171,382,1675,530,1598,2561,356,99,245,986,926,1037,2260,204,154,434,1049,1020
0.09415745775210213,1.894487649782089,-0.11827242278503895,0.7358896549563253,0.4745792189320432,2.1279058027565836,1.3082387048731943,1.6838460454736341,0.9824120538036047,-0.22847370331607397,0.7358896549563253,-0.19143174128541807,-0.8464982748968118,1.0384421790618117,2.1279058027565836,1.373145758933382,0.21347933237869962,0.2636380221709174,0.17971792076718154,-0.596873097659703,1.537489972244893,1.7787349139536996,0.8969895762705655,0.17971792076718154,0.1966311801772001
2,948
Protein targeting
29
117
2.993981
0.002754
P55786,Q9Y584,Q9Y512,Q9NS69,P46934,Q15629,O43464,O60725,Q9H270,Q14108,Q9UGP8,Q99595,Q9P0J0,P40855,O95140,Q8N4H5,O95831,P43307,Q5JRX3,P31751,Q9H300,Q9Y5J7,Q9Y5J9,O60220,Q99523,P33908,O60830,Q99797,Q5THJ4
Processes and pathways
GO Biological process
msigdb_gobp
2,133,260,7,20,148,400,29,415,162,168,42,176,427,426,182,57,58,59,194,325,199,336,337,213,355,106,374,254
2273,627,850,1992,1618,551,2928,552,501,400,791,1073,1936,337,29,106,1191,1860,2601,1443,426,2086,1393,57,2238,1416,1164,2527,977,1251,2506,819,921,1447,2840,2900,2109,194,1194,355,2147,2282,427,58,871,20,646,1202,1669,1594,1094,2,922,2537,2801,2302,923,800,664,983,1832,1543,1948,1507,447,1736,754,162,1283,2650,1082,148,1898,840,947,1839,59,254,1233,963,2255,1901,1516,182,1457,1846,1713,1925,1606,213,1521,42,374,415,325,1354,2935,7,1431,176,2444,1882,168,1788,2519,905,2370,1751,1358,2103,2445,260,133,199,336,906,598
-0.6171437624952562,0.5840797855852801,0.3296339066521189,-0.43798169806465925,-0.20991366611478418,0.7059476590359905,-2.8388595641615995,0.7059476590359905,0.7804203434389911,0.9399105014520449,0.394648358795702,0.1456940908786263,-0.3991392521076305,1.0937591810735925,3.0494454126243524,2.0844088865487853,0.05945972020734923,-0.34151131793657324,-0.9111754241704362,-0.1001715700836958,0.8969895762705655,-0.4968959727005952,-0.06419237620988717,2.6085391476555078,-0.596873097659703,-0.08214508712671734,0.07684293929142288,-0.825148078218146,0.21347933237869962,0.024485024344763594,-0.8039006614231072,0.36226201680927644,0.2636380221709174,-0.1001715700836958,-1.465757012993624,-1.8781849174669127,-0.5167106212981979,1.5868275562513716,0.05945972020734923,1.0384421790618117,-0.5366148538627052,-0.6171437624952562,0.8969895762705655,2.6085391476555078,0.31322807591179413,3.178401473028381,0.5686040539973861,0.05945972020734923,-0.22847370331607397,-0.19143174128541807,0.12858251145984356,3.711080088907221,0.2636380221709174,-0.825148078218146,-1.32046570987856,-0.6375081142813843,0.2636380221709174,0.394648358795702,0.5530732376857973,0.21347933237869962,-0.3224686466679636,-0.154699664595971,-0.3991392521076305,-0.1364482501831472,0.8825879960378804,-0.26583072691689574,0.4427821773887004,1.7315509278111096,0.00689245382919885,-0.9768137628162359,0.1456940908786263,1.8137877280347836,-0.36063683389058815,0.3459784040561311,0.24698227118508845,-0.3224686466679636,2.5794159618228156,1.3472994325027918,0.04200726311648557,0.23026286775039087,-0.596873097659703,-0.36063683389058815,-0.1364482501831472,1.6477186929262733,-0.1001715700836958,-0.3224686466679636,-0.24711250387957184,-0.3798459053107705,-0.19143174128541807,1.5126086522989541,-0.1364482501831472,2.8712191617408704,0.9964874283803038,0.925650523668678,1.1347895625307758,-0.028505915233174372,-3.6036010998151187,3.496511927362126,-0.08214508712671734,1.6718371053502799,-0.7407654856874151,-0.34151131793657324,1.7077643034433876,-0.28462903979626186,-0.8039006614231072,0.2967604582024043,-0.6785213070020842,-0.26583072691689574,-0.028505915233174372,-0.4968959727005952,-0.7407654856874151,1.3343182502559603,1.917270315417413,1.574545797147203,1.1074790838974617,0.2967604582024043,0.6454394534643092
2,948
Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen
13
26
2.98652
0.002822
Q32P28,P09601,O75845,P61457,Q14534,Q8NB78,Q15800,Q16850,Q9NWT6,P13674,O95864,P30519,Q6UW02
Functions
GO Molecular function
msigdb_gomf
198,101,201,138,272,369,246,52,376,55,26,28,318
607,398,2861,2745,201,26,526,101,55,663,28,138,1372,724,272,246,52,198,1515,318,2254,369,1218,2493,376,760
0.6148675201656797,0.9399105014520449,-1.5905769604580335,-1.1567689963310013,1.549877201936574,3.0842161304682922,0.7358896549563253,2.1170726813344136,2.627845336521186,0.5530732376857973,3.058164653086549,1.8715840661178529,-0.046312846762206455,0.4745792189320432,1.2820013709130165,1.373145758933382,2.6852478237468818,1.574545797147203,-0.1364482501831472,1.1483806684923388,-0.596873097659703,1.0105173832723406,0.05945972020734923,-0.7827550573182713,0.9964874283803038,0.4427821773887004
2,948
Metalloendopeptidase activity
8
15
2.975362
0.002926
Q96E52,P42892,Q99797,Q9BYT8,O75844,Q5JRX3,Q10713,O43847
Functions
GO Molecular function
msigdb_gomf
229,16,374,186,121,59,447,189
189,1860,121,1395,477,16,1204,447,59,880,229,1044,374,186,655
1.611286969212316,-0.34151131793657324,1.9624778628651733,-0.06419237620988717,0.8245003681365923,3.245617927748801,0.05945972020734923,0.8825879960378804,2.5794159618228156,0.31322807591179413,1.4243805350193866,0.17971792076718154,0.9964874283803038,1.6356088521917012,0.5686040539973861
2,948
Membrane lipid metabolic process
17
35
2.973697
0.002942
Q92643,Q9NZ01,Q8NCC3,Q5H8A4,Q96G23,P06280,P04066,P30153,P07602,P50897,Q99805,P27544,Q8NBX0,O95470,O43464,O60762,Q9NZJ7
Processes and pathways
GO Biological process
msigdb_gobp
542,653,3,195,72,708,238,587,110,144,241,303,114,214,400,659,517
1491,1072,1722,400,659,214,707,238,708,998,110,2780,978,979,1470,303,587,144,1006,1033,1839,195,114,3,542,845,72,898,241,1608,1880,1611,653,517,848
-0.1364482501831472,0.1456940908786263,-0.26583072691689574,0.9399105014520449,0.5530732376857973,1.5001141584399327,0.4903913364797827,1.3860113542851535,0.4903913364797827,0.1966311801772001,2.06249462948218,-1.2495678211004613,0.21347933237869962,0.21347933237869962,-0.11827242278503895,1.1754359209634744,0.660645419060983,1.8485582976056778,0.1966311801772001,0.17971792076718154,-0.3224686466679636,1.5868275562513716,2.018328951139827,3.711080088907221,0.7209443730522314,0.3459784040561311,2.369826344771198,0.2967604582024043,1.3860113542851535,-0.19143174128541807,-0.34151131793657324,-0.19143174128541807,0.5686040539973861,0.7656273000310847,0.3459784040561311
2,948
Morphological abnormality of the pyramidal tract
7
22
2.959718
0.003079
P35637,Q9H9P8,O75569,Q9Y619,O95831,P00846,O75298
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
98,169,170,81,57,60,95
236,1528,95,170,1995,57,60,810,1279,98,1733,1949,649,1008,2561,985,422,169,1185,2133,2270,81
1.3860113542851535,-0.154699664595971,2.170967820101334,1.6838460454736341,-0.43798169806465925,2.6085391476555078,2.530433704556057,0.37848518872114384,0.00689245382919885,2.1279058027565836,-0.26583072691689574,-0.3991392521076305,0.5686040539973861,0.1966311801772001,-0.8464982748968118,0.21347933237869962,0.9113436498871638,1.6958217180030357,0.07684293929142288,-0.5167106212981979,-0.596873097659703,2.3183799967279364
2,948
Intracellular protein transmembrane transport
6
20
2.936602
0.003318
Q9UGP8,Q99595,O60830,Q15629,O95831,O75298
Processes and pathways
GO Biological process
msigdb_gobp
168,42,106,148,57,95
552,791,106,95,1191,1443,57,2238,2527,194,2537,2302,923,1082,148,947,1606,42,1354,168
0.7059476590359905,0.394648358795702,2.0844088865487853,2.170967820101334,0.05945972020734923,-0.1001715700836958,2.6085391476555078,-0.596873097659703,-0.825148078218146,1.5868275562513716,-0.825148078218146,-0.6375081142813843,0.2636380221709174,0.1456940908786263,1.8137877280347836,0.24698227118508845,-0.19143174128541807,2.8712191617408704,-0.028505915233174372,1.7077643034433876
2,948
Glycoprotein biosynthetic process
16
47
2.92558
0.003438
O43505,O15118,P33908,Q04656,Q9NQX7,Q9HC07,Q10472,Q99805,Q8NCH0,P35610,Q8N4A0,Q7LGA3,O60502,Q08379,Q9BT22,Q8TCJ2
Processes and pathways
GO Biological process
msigdb_gobp
65,129,355,322,142,43,430,241,113,178,54,342,281,446,285,373
790,129,1440,65,281,736,659,1442,2447,2141,1250,1757,355,1759,178,2243,893,2092,1372,322,2405,446,739,430,1404,1454,540,342,843,54,2808,113,373,681,713,456,241,285,1523,731,2632,43,142,1242,2519,1490,1819
0.394648358795702,1.917270315417413,-0.1001715700836958,2.4408320972461683,1.2556043625519968,0.4587096364267473,0.5530732376857973,-0.1001715700836958,-0.7617103122164987,-0.5366148538627052,0.024485024344763594,-0.28462903979626186,1.0384421790618117,-0.28462903979626186,1.6597947156561212,-0.596873097659703,0.2967604582024043,-0.4968959727005952,-0.046312846762206455,1.1347895625307758,-0.7199196503135434,0.8825879960378804,0.4587096364267473,0.8969895762705655,-0.06419237620988717,-0.1001715700836958,0.7209443730522314,1.0937591810735925,0.3459784040561311,2.65664263773781,-1.344352687464858,2.0294128700184095,0.9964874283803038,0.537486950272112,0.4903913364797827,0.8681385994260129,1.3860113542851535,1.2556043625519968,-0.1364482501831472,0.4745792189320432,-0.9548257864570027,2.8712191617408704,1.8715840661178529,0.04200726311648557,-0.8039006614231072,-0.11827242278503895,-0.3035081182804855
2,948
Inorganic molecular entity transmembrane transporter activity
35
84
2.924243
0.003453
Q9Y277,P56385,Q96ER9,P16615,Q9UDW1,Q15043,Q9C0H2,P06576,P51790,P05026,Q93050,Q96S66,P35670,Q7KZN9,Q9HC07,P00403,O75964,P13073,Q8N4V1,P00846,P45880,Q04656,Q9NW15,Q13423,Q9Y487,Q8IUH4,Q9HD20,P20674,Q9UBX3,Q6P4Q7,O00400,P21796,Q99797,Q96QD8,Q8TAD4
Functions
GO Molecular function
msigdb_gomf
654,648,397,644,274,404,150,402,282,660,27,545,538,431,43,174,302,688,450,60,71,322,334,216,89,601,94,610,230,490,236,111,374,118,117
1693,236,1439,1073,1824,302,697,174,60,794,660,749,402,1827,1163,809,2107,795,1362,1564,688,644,2091,1112,610,1253,2765,111,1225,980,2377,1338,538,1397,750,2217,71,2793,2747,282,1763,2844,766,648,1029,923,2883,836,1507,1171,322,216,404,1036,2666,490,431,601,450,1040,117,1101,27,397,1269,118,545,2932,374,150,917,1385,43,94,2903,334,230,274,2167,950,654,89,1188,2553
-0.24711250387957184,1.3860113542851535,-0.1001715700836958,0.1456940908786263,-0.3224686466679636,1.1754359209634744,0.5061463962970855,1.6718371053502799,2.530433704556057,0.394648358795702,0.5530732376857973,0.4427821773887004,0.9399105014520449,-0.3224686466679636,0.07684293929142288,0.37848518872114384,-0.5167106212981979,0.394648358795702,-0.046312846762206455,-0.17302728582659577,0.5218448013237352,0.5686040539973861,-0.4968959727005952,0.11140380677844741,0.6148675201656797,0.024485024344763594,-1.2029252754937023,2.0514955668887254,0.04200726311648557,0.21347933237869962,-0.6991718914520957,-0.028505915233174372,0.7209443730522314,-0.06419237620988717,0.4427821773887004,-0.576695277069889,2.369826344771198,-1.2967067971056643,-1.1567689963310013,1.2556043625519968,-0.28462903979626186,-1.4904417735103144,0.4267964258326052,0.5686040539973861,0.17971792076718154,0.2636380221709174,-1.7451438249828646,0.3459784040561311,-0.1364482501831472,0.07684293929142288,1.1347895625307758,1.4875835034045466,0.9399105014520449,0.17971792076718154,-0.9989116898321668,0.8098565473687283,0.8969895762705655,0.6301802761408241,0.8825879960378804,0.17971792076718154,1.9960752529228047,0.12858251145984356,3.0842161304682922,0.954123884167548,0.024485024344763594,1.9960752529228047,0.7209443730522314,-3.2232065341232468,0.9964874283803038,1.8137877280347836,0.2802305948711232,-0.046312846762206455,2.8712191617408704,2.1816663680647275,-1.9052771337681562,1.121155788951183,1.4243805350193866,1.2820013709130165,-0.5366148538627052,0.24698227118508845,0.5686040539973861,2.2347638458248005,0.07684293929142288,-0.825148078218146
2,948
protein modifying enzyme
7
20
2.909031
0.003626
P33908,Q92791,P50897,O75718,P13674,Q15102,O60725
Functions
Panther Protein class
panther_protein_class
355,44,144,21,55,123,29
1391,1440,398,1306,29,21,55,355,144,1095,1372,724,123,1513,1038,566,44,604,1523,2803
-0.06419237620988717,-0.1001715700836958,0.9399105014520449,-0.010771004982313778,3.0494454126243524,3.1529198842609487,2.627845336521186,1.0384421790618117,1.8485582976056778,0.12858251145984356,-0.046312846762206455,0.4745792189320432,1.9512203158872787,-0.1364482501831472,0.17971792076718154,0.6908991641556643,2.8529812632786027,0.6301802761408241,-0.1364482501831472,-1.32046570987856
2,948
Mitochondrial protein import
18
37
2.903397
0.003691
Q9Y584,Q9Y512,Q9Y5J7,Q9NS69,Q99595,Q9NX63,P12236,O60830,Q9Y5J9,P21796,O60220,O75431,Q9Y276,Q13505,Q8N4H5,P06576,Q5JRX3,Q10713
Processes and pathways
Reactome Pathways
msigdb_reactome
133,260,199,7,42,436,362,106,336,111,337,338,508,244,182,402,59,447
552,791,337,106,2856,338,1860,888,1443,2238,402,2107,2527,1564,362,111,2377,2508,664,447,244,1082,947,59,182,42,2890,1354,7,436,1328,508,260,133,199,336,906
0.7059476590359905,0.394648358795702,1.0937591810735925,2.0844088865487853,-1.5653306411594137,1.0937591810735925,-0.34151131793657324,0.2967604582024043,-0.1001715700836958,-0.596873097659703,0.9399105014520449,-0.5167106212981979,-0.825148078218146,-0.17302728582659577,1.0245022054180684,2.0514955668887254,-0.6991718914520957,-0.8039006614231072,0.5530732376857973,0.8825879960378804,1.373145758933382,0.1456940908786263,0.24698227118508845,2.5794159618228156,1.6477186929262733,2.8712191617408704,-1.7978838385941391,-0.028505915233174372,3.496511927362126,0.8969895762705655,-0.010771004982313778,0.7804203434389911,1.3343182502559603,1.917270315417413,1.574545797147203,1.1074790838974617,0.2967604582024043
2,948
Regulation of mrna splicing via spliceosome
23
56
2.886657
0.003894
P51114,P38159,O75494,P61978,P31483,Q06787,Q9BWF3,Q07666,P51116,P09651,Q08170,Q9UHX1,Q13242,Q96PU8,Q96E39,Q16629,Q14011,P22626,Q07021,P62995,P98179,P26368,P98175
Processes and pathways
GO Biological process
msigdb_gobp
256,130,390,139,392,530,280,288,420,294,556,61,329,591,211,597,99,227,226,228,102,239,382
2206,390,1624,294,1251,1469,833,2212,1699,227,239,1862,2577,392,130,2399,256,420,765,1542,139,228,2888,1030,382,102,1675,530,226,288,556,1344,2220,329,1478,1403,631,99,699,913,597,1775,2606,2831,712,211,1105,1520,591,2547,280,1852,61,2203,1020,996
-0.576695277069889,0.954123884167548,-0.20991366611478418,1.202323609529759,0.024485024344763594,-0.11827242278503895,0.3459784040561311,-0.576695277069889,-0.24711250387957184,1.4243805350193866,1.3860113542851535,-0.34151131793657324,-0.8679522324143034,0.954123884167548,1.917270315417413,-0.7199196503135434,1.3343182502559603,0.9113436498871638,0.4267964258326052,-0.154699664595971,1.8715840661178529,1.4243805350193866,-1.7978838385941391,0.17971792076718154,0.9824120538036047,2.1170726813344136,-0.22847370331607397,0.7358896549563253,1.4370951229364066,1.2423453819314823,0.7059476590359905,-0.028505915233174372,-0.576695277069889,1.121155788951183,-0.11827242278503895,-0.06419237620988717,0.5840797855852801,2.1279058027565836,0.5061463962970855,0.2802305948711232,0.6454394534643092,-0.28462903979626186,-0.9111754241704362,-1.4167957453667614,0.4903913364797827,1.5250671893501497,0.12858251145984356,-0.1364482501831472,0.660645419060983,-0.825148078218146,1.2688229452074793,-0.3224686466679636,2.530433704556057,-0.5566094692716574,0.1966311801772001,0.21347933237869962
2,948
Organic anion transport
14
42
2.881865
0.003953
Q9H2D1,Q9UBX3,Q8TB61,P12236,O00400,O60831,P07602,Q9Y619,Q9NY64,P53985,Q96QD8,Q9BQT8,Q08722,P30825
Processes and pathways
GO Biological process
msigdb_gobp
4,230,267,362,236,365,110,81,408,50,118,23,275,221
236,2928,441,365,888,641,1223,749,1307,110,809,1564,362,643,1396,1139,221,1629,50,2844,1171,275,2650,1122,1284,927,1923,267,624,916,118,23,4,917,1385,804,934,408,517,230,1328,81
1.3860113542851535,-2.8388595641615995,0.8825879960378804,1.0105173832723406,0.2967604582024043,0.5686040539973861,0.04200726311648557,0.4427821773887004,-0.010771004982313778,2.06249462948218,0.37848518872114384,-0.17302728582659577,1.0245022054180684,0.5686040539973861,-0.06419237620988717,0.09415745775210213,1.4624128836284802,-0.20991366611478418,2.7136633954590907,-1.4904417735103144,0.07684293929142288,1.2688229452074793,-0.9768137628162359,0.11140380677844741,0.00689245382919885,0.2636380221709174,-0.3798459053107705,1.3082387048731943,0.5995008148293052,0.2802305948711232,1.9960752529228047,3.118706149066854,3.666003780285035,0.2802305948711232,-0.046312846762206455,0.394648358795702,0.2636380221709174,0.9399105014520449,0.7656273000310847,1.4243805350193866,-0.010771004982313778,2.3183799967279364
2,948
Active transmembrane transporter activity
19
73
2.880962
0.003965
P03886,Q9UDW1,Q15043,P06576,O43676,P51790,O96000,Q7KZN9,Q9P0J0,P00403,P53985,Q04656,Q9Y6M9,Q9HD20,Q9UBX3,P08183,P12236,O00400,Q96QD8
Functions
GO Molecular function
msigdb_gomf
145,274,404,402,24,282,36,431,176,174,50,322,220,94,230,107,362,236,118
236,2024,1439,1619,24,425,2047,1968,1247,1659,2627,697,2602,36,174,145,794,660,749,402,107,809,2107,1362,1564,362,688,644,2395,1112,610,1253,2765,1225,1139,2823,1338,538,750,2217,2793,2748,282,1763,2178,1629,50,2844,1029,2883,836,1171,676,322,404,1082,1284,1345,2289,431,1040,1269,118,917,1385,94,1931,176,230,274,2167,1188,220
1.3860113542851535,-0.45753228412024466,-0.1001715700836958,-0.20991366611478418,3.1101097166990783,0.8969895762705655,-0.4771701196736191,-0.41851760347793965,0.024485024344763594,-0.22847370331607397,-0.9548257864570027,0.5061463962970855,-0.9111754241704362,2.943403293840926,1.6718371053502799,1.8369991927238165,0.394648358795702,0.5530732376857973,0.4427821773887004,0.9399105014520449,2.0844088865487853,0.37848518872114384,-0.5167106212981979,-0.046312846762206455,-0.17302728582659577,1.0245022054180684,0.5218448013237352,0.5686040539973861,-0.7199196503135434,0.11140380677844741,0.6148675201656797,0.024485024344763594,-1.2029252754937023,0.04200726311648557,0.09415745775210213,-1.392516309666817,-0.028505915233174372,0.7209443730522314,0.4427821773887004,-0.576695277069889,-1.2967067971056643,-1.1567689963310013,1.2556043625519968,-0.28462903979626186,-0.5566094692716574,-0.20991366611478418,2.7136633954590907,-1.4904417735103144,0.17971792076718154,-1.7451438249828646,0.3459784040561311,0.07684293929142288,0.537486950272112,1.1347895625307758,0.9399105014520449,0.1456940908786263,0.00689245382919885,-0.028505915233174372,-0.6171437624952562,0.8969895762705655,0.17971792076718154,0.024485024344763594,1.9960752529228047,0.2802305948711232,-0.046312846762206455,2.1816663680647275,-0.3798459053107705,1.6718371053502799,1.4243805350193866,1.2820013709130165,-0.5366148538627052,0.07684293929142288,1.4750164810877993
2,948
Nadh dehydrogenase complex assembly
10
26
2.879075
0.003988
Q9H061,O96000,Q9P0J0,P03886,Q8IUX1,Q96CU9,Q86Y39,O43676,Q7L592,Q9Y6M9
Processes and pathways
GO Biological process
msigdb_gobp
132,36,176,145,273,210,309,24,251,220
24,2047,1968,1247,1659,2602,36,145,2823,2178,323,1345,2289,251,309,273,2622,210,132,1411,1068,1854,176,508,1220,220
3.1101097166990783,-0.4771701196736191,-0.41851760347793965,0.024485024344763594,-0.22847370331607397,-0.9111754241704362,2.943403293840926,1.8369991927238165,-1.392516309666817,-0.5566094692716574,1.1347895625307758,-0.028505915233174372,-0.6171437624952562,1.3602418598724249,1.161929368281666,1.2820013709130165,-0.9329466915129715,1.5250671893501497,1.917270315417413,-0.06419237620988717,0.16273905820118395,-0.3224686466679636,1.6718371053502799,0.7804203434389911,0.05945972020734923,1.4750164810877993
2,948
Rna stabilization
10
27
2.858182
0.004261
P35637,Q14011,Q13151,O60506,P49137,P67809,Q92804,Q14103,P98175,Q08J23
Processes and pathways
GO Biological process
msigdb_gobp
98,99,356,135,265,171,204,245,382,222
135,1938,1464,1724,527,719,98,265,171,382,1675,1598,222,2561,356,99,245,986,926,1037,2260,204,434,1648,1240,1049,1020
1.894487649782089,-0.3991392521076305,-0.11827242278503895,-0.26583072691689574,0.7358896549563253,0.4745792189320432,2.1279058027565836,1.3082387048731943,1.6838460454736341,0.9824120538036047,-0.22847370331607397,-0.19143174128541807,1.4624128836284802,-0.8464982748968118,1.0384421790618117,2.1279058027565836,1.373145758933382,0.21347933237869962,0.2636380221709174,0.17971792076718154,-0.596873097659703,1.537489972244893,0.8969895762705655,-0.20991366611478418,0.04200726311648557,0.17971792076718154,0.1966311801772001
2,948
Translocation
12
50
2.83958
0.004517
Q9Y584,Q9Y5J7,Q9NS69,Q99595,Q8NFH4,O60830,Q9BTX1,Q9Y5J9,O60220,Q8TD16,Q15629,Q5SRE5
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
133,199,7,42,331,106,206,336,337,209,148,277
2273,552,791,337,106,1191,887,1445,1228,1760,2662,1367,1542,1141,2537,923,2115,664,1803,1677,148,947,2409,277,963,395,2623,331,815,209,1458,1267,1459,1104,1606,827,42,206,2441,1066,949,2625,7,1855,1387,1818,133,199,336,906
-0.6171437624952562,0.7059476590359905,0.394648358795702,1.0937591810735925,2.0844088865487853,0.05945972020734923,0.2967604582024043,-0.1001715700836958,0.04200726311648557,-0.28462903979626186,-0.9989116898321668,-0.046312846762206455,-0.154699664595971,0.09415745775210213,-0.825148078218146,0.2636380221709174,-0.5167106212981979,0.5530732376857973,-0.3035081182804855,-0.22847370331607397,1.8137877280347836,0.24698227118508845,-0.7199196503135434,1.2688229452074793,0.23026286775039087,0.954123884167548,-0.9329466915129715,1.121155788951183,0.37848518872114384,1.5250671893501497,-0.1001715700836958,0.024485024344763594,-0.1001715700836958,0.12858251145984356,-0.19143174128541807,0.36226201680927644,2.8712191617408704,1.537489972244893,-0.7407654856874151,0.16273905820118395,0.24698227118508845,-0.9329466915129715,3.496511927362126,-0.3224686466679636,-0.046312846762206455,-0.3035081182804855,1.917270315417413,1.574545797147203,1.1074790838974617,0.2967604582024043
2,948
Electron transport
14
43
2.835269
0.004579
O96000,Q16134,Q9H1E5,O43169,Q9P0J0,P00403,P03886,Q9UDW1,Q96CU9,O14949,Q6DKK2,O95864,Q9Y6M9,O43676
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
36,262,104,14,176,174,145,274,210,151,152,26,220,24
2024,151,14,385,24,2047,1968,1247,1659,2627,2602,26,36,174,145,2107,2717,1363,2395,870,2756,477,2823,1889,1338,2353,2507,2793,2748,2178,262,1345,2289,152,309,210,1155,104,577,1068,176,274,220
-0.45753228412024466,1.8021350389030668,3.2622578968216644,0.968290969875735,3.1101097166990783,-0.4771701196736191,-0.41851760347793965,0.024485024344763594,-0.22847370331607397,-0.9548257864570027,-0.9111754241704362,3.0842161304682922,2.943403293840926,1.6718371053502799,1.8369991927238165,-0.5167106212981979,-1.0884248463707054,-0.046312846762206455,-0.7199196503135434,0.31322807591179413,-1.1797869757098827,0.8245003681365923,-1.392516309666817,-0.36063683389058815,-0.028505915233174372,-0.6785213070020842,-0.8039006614231072,-1.2967067971056643,-1.1567689963310013,-0.5566094692716574,1.3212980845713802,-0.028505915233174372,-0.6171437624952562,1.8021350389030668,1.161929368281666,1.5250671893501497,0.09415745775210213,2.095324359314597,0.6757985361220961,0.16273905820118395,1.6718371053502799,1.2820013709130165,1.4750164810877993
2,948
Mitochondrial membrane organization
25
54
2.830672
0.004645
Q9Y4W6,Q9Y584,Q9Y512,Q9NS69,P62072,Q6UXV4,Q9NVH1,P0DP25,Q9NX63,Q9P0J0,O14737,O95140,Q16891,Q9BUR5,O95202,Q9Y5J7,Q15070,P45880,Q9Y5J9,O60220,O75431,O60313,Q96E52,Q13505,Q9Y276
Processes and pathways
GO Biological process
msigdb_gobp
655,133,260,7,664,666,549,674,436,176,551,426,564,183,697,199,323,71,336,337,338,460,229,244,508
1992,551,337,460,1245,338,1443,426,697,2376,749,1416,2350,674,1564,2578,2352,2147,2508,2746,71,1628,1669,1670,811,664,1006,244,2184,323,564,947,1839,1231,860,666,1711,1424,229,183,730,7,549,436,176,905,508,655,260,133,199,336,906,2667
-0.43798169806465925,0.7059476590359905,1.0937591810735925,0.8390951028692502,0.024485024344763594,1.0937591810735925,-0.1001715700836958,0.8969895762705655,0.5061463962970855,-0.6991718914520957,0.4427821773887004,-0.08214508712671734,-0.6785213070020842,0.537486950272112,-0.17302728582659577,-0.8679522324143034,-0.6785213070020842,-0.5366148538627052,-0.8039006614231072,-1.1567689963310013,2.369826344771198,-0.20991366611478418,-0.22847370331607397,-0.22847370331607397,0.37848518872114384,0.5530732376857973,0.1966311801772001,1.373145758933382,-0.5566094692716574,1.1347895625307758,0.6908991641556643,0.24698227118508845,-0.3224686466679636,0.04200726311648557,0.3296339066521189,0.5530732376857973,-0.24711250387957184,-0.08214508712671734,1.4243805350193866,1.6477186929262733,0.4745792189320432,3.496511927362126,0.7209443730522314,0.8969895762705655,1.6718371053502799,0.2967604582024043,0.7804203434389911,0.5686040539973861,1.3343182502559603,1.917270315417413,1.574545797147203,1.1074790838974617,0.2967604582024043,-0.9989116898321668
2,948
Tetrapyrrole binding
11
19
2.814458
0.004886
Q8WUJ1,P09601,Q9NRV9,Q7KZN9,O43169,O15173,Q16850,P30519,Q6UW02,O00264,P53701
Functions
GO Molecular function
msigdb_gomf
161,101,559,431,14,80,52,28,318,92,478
92,80,14,2107,101,1727,28,478,52,318,431,161,1779,967,932,578,2551,559,2667
2.1816663680647275,2.3183799967279364,3.2622578968216644,-0.5167106212981979,2.1170726813344136,-0.26583072691689574,3.058164653086549,0.8245003681365923,2.6852478237468818,1.1483806684923388,0.8969895762705655,1.7552073337708918,-0.28462903979626186,0.23026286775039087,0.2636380221709174,0.6757985361220961,-0.825148078218146,0.7059476590359905,-0.9989116898321668
2,948
Early endosome
24
86
2.807061
0.005
Q9UIQ6,Q15043,P51790,Q9H270,Q8IV08,Q9HC07,Q5VW38,Q96L92,O60749,Q9BUN8,Q8N4V1,O95630,P02786,P31751,Q04656,P01889,Q92783,Q99523,P04439,P11717,P10321,O43752,O15400,O14964
Localization
GO Cellular component
msigdb_gocc
12,404,282,415,166,43,46,306,48,53,450,192,442,194,322,339,212,213,348,350,475,360,237,501
2655,501,237,360,1937,1305,48,2478,778,793,2048,192,339,442,1223,348,475,2527,350,1309,909,2213,1138,2840,1534,2533,194,1795,1541,282,1002,1097,1029,1703,1004,1735,322,649,2564,1033,2004,2852,839,404,2617,1406,896,1149,46,1840,2255,2311,166,450,878,681,2012,212,516,306,1380,213,899,2440,53,2820,1879,992,901,1556,415,1325,43,1219,2517,1856,1525,12,1789,1933,671,1751,735,1298,717,582
-0.9989116898321668,0.7804203434389911,1.3860113542851535,1.0245022054180684,-0.3991392521076305,-0.010771004982313778,2.741891805558301,-0.7827550573182713,0.4107519613001489,0.394648358795702,-0.4771701196736191,1.5990745493593614,1.0937591810735925,0.8825879960378804,0.04200726311648557,1.06618870455087,0.8245003681365923,-0.825148078218146,1.0523375857873305,-0.010771004982313778,0.2802305948711232,-0.576695277069889,0.09415745775210213,-1.465757012993624,-0.154699664595971,-0.825148078218146,1.5868275562513716,-0.3035081182804855,-0.154699664595971,1.2556043625519968,0.1966311801772001,0.12858251145984356,0.17971792076718154,-0.24711250387957184,0.1966311801772001,-0.26583072691689574,1.1347895625307758,0.5686040539973861,-0.8464982748968118,0.17971792076718154,-0.43798169806465925,-1.540227049969209,0.3459784040561311,0.9399105014520449,-0.9329466915129715,-0.06419237620988717,0.2967604582024043,0.09415745775210213,2.7792426967582533,-0.3224686466679636,-0.596873097659703,-0.6375081142813843,1.7077643034433876,0.8825879960378804,0.31322807591179413,0.537486950272112,-0.43798169806465925,1.5126086522989541,0.7656273000310847,1.1754359209634744,-0.046312846762206455,1.5126086522989541,0.2967604582024043,-0.7407654856874151,2.6852478237468818,-1.3683690925791896,-0.34151131793657324,0.21347933237869962,0.2967604582024043,-0.154699664595971,0.925650523668678,-0.010771004982313778,2.8712191617408704,0.05945972020734923,-0.8039006614231072,-0.3224686466679636,-0.1364482501831472,3.368863420764839,-0.28462903979626186,-0.3798459053107705,0.5530732376857973,-0.26583072691689574,0.4745792189320432,0.00689245382919885,0.4903913364797827,0.6757985361220961
2,948
Endoplasmic reticulum golgi intermediate compartment membrane
12
27
2.806772
0.005004
P53634,O95070,P49755,P49257,Q10472,P24390,Q12907,Q96RQ1,Q8N511,Q15904,Q08379,Q9Y282
Localization
GO Cellular component
msigdb_gocc
445,361,554,646,430,15,620,180,149,463,446,62
868,1221,1619,1755,361,15,2280,646,554,1094,445,1096,676,446,430,620,2333,1209,463,149,1290,1579,180,1956,62,1300,1244
0.31322807591179413,0.04200726311648557,-0.20991366611478418,-0.28462903979626186,1.0245022054180684,3.2622578968216644,-0.6171437624952562,0.5686040539973861,0.7059476590359905,0.12858251145984356,0.8825879960378804,0.12858251145984356,0.537486950272112,0.8825879960378804,0.8969895762705655,0.5995008148293052,-0.6579670071768167,0.05945972020734923,0.8390951028692502,1.8137877280347836,0.00689245382919885,-0.17302728582659577,1.6597947156561212,-0.3991392521076305,2.5106832011938405,0.00689245382919885,0.04200726311648557
2,948
Dementia
21
57
2.774648
0.005526
O15118,P31483,P03886,Q06787,O43464,Q14108,P35670,P09651,P00403,P27544,O76024,P00846,Q9NQZ5,P43243,O60220,O60313,Q9Y487,P35637,P22626,P07602,Q9NZJ7
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
129,392,145,530,400,162,538,294,174,303,313,60,64,452,337,460,89,98,227,110,517
628,129,400,1073,337,460,2478,313,2238,174,60,145,707,2821,537,998,110,294,2641,979,1113,870,227,2614,303,1889,392,98,538,750,2217,452,1920,1894,1733,1768,1705,530,2561,1033,162,985,1375,1064,2010,1552,2368,1380,1713,2865,64,2919,517,1185,1018,1490,89
0.5840797855852801,1.917270315417413,0.9399105014520449,0.1456940908786263,1.0937591810735925,0.8390951028692502,-0.7827550573182713,1.1483806684923388,-0.596873097659703,1.6718371053502799,2.530433704556057,1.8369991927238165,0.4903913364797827,-1.392516309666817,0.7209443730522314,0.1966311801772001,2.06249462948218,1.202323609529759,-0.9768137628162359,0.21347933237869962,0.11140380677844741,0.31322807591179413,1.4243805350193866,-0.9329466915129715,1.1754359209634744,-0.36063683389058815,0.954123884167548,2.1279058027565836,0.7209443730522314,0.4427821773887004,-0.576695277069889,0.8681385994260129,-0.3798459053107705,-0.36063683389058815,-0.26583072691689574,-0.28462903979626186,-0.24711250387957184,0.7358896549563253,-0.8464982748968118,0.17971792076718154,1.7315509278111096,0.21347933237869962,-0.046312846762206455,0.16273905820118395,-0.43798169806465925,-0.154699664595971,-0.6785213070020842,-0.046312846762206455,-0.24711250387957184,-1.5905769604580335,2.4508806535723897,-2.332755838948225,0.7656273000310847,0.07684293929142288,0.1966311801772001,-0.11827242278503895,2.2347638458248005
2,948
Endoplasmic reticulum lumen
21
55
2.762207
0.005741
Q07065,Q96AY3,O75718,P07237,O15460,Q14257,Q8NBJ5,P13674,Q9NWM8,O76024,P53634,Q32P28,O43852,Q14697,Q9BS26,Q9Y680,Q9BTY2,Q9NZ08,Q15293,Q12841,Q02818
Localization
GO Cellular component
msigdb_gocc
257,534,21,526,398,41,566,55,187,313,445,198,74,595,605,90,357,105,621,371,126
398,1073,74,21,313,853,526,2323,977,2628,2088,55,2175,1829,2836,2822,1138,2280,1863,1534,1025,2053,1730,445,126,257,371,1032,41,595,2119,621,198,987,2095,843,1210,635,566,2808,1742,1427,1429,534,1155,605,2827,357,2077,187,1242,105,1356,1691,90
0.9399105014520449,0.1456940908786263,2.3493216246615503,3.1529198842609487,1.1483806684923388,0.3296339066521189,0.7358896549563253,-0.6579670071768167,0.21347933237869962,-0.9548257864570027,-0.4968959727005952,2.627845336521186,-0.5566094692716574,-0.3224686466679636,-1.4412088289871978,-1.392516309666817,0.09415745775210213,-0.6171437624952562,-0.34151131793657324,-0.154699664595971,0.17971792076718154,-0.4771701196736191,-0.26583072691689574,0.8825879960378804,1.9399333103611618,1.3343182502559603,0.9964874283803038,0.17971792076718154,2.8712191617408704,0.6454394534643092,-0.5167106212981979,0.5995008148293052,1.574545797147203,0.21347933237869962,-0.4968959727005952,0.3459784040561311,0.05945972020734923,0.5840797855852801,0.6908991641556643,-1.344352687464858,-0.26583072691689574,-0.08214508712671734,-0.08214508712671734,0.7358896549563253,0.09415745775210213,0.6301802761408241,-1.392516309666817,1.0384421790618117,-0.4771701196736191,1.6356088521917012,0.04200726311648557,2.095324359314597,-0.028505915233174372,-0.22847370331607397,2.2136033965250372
2,948
Vesicles
64
283
2.761864
0.005747
Q9NPR9,Q8NCC3,O15118,P42785,O75153,O60506,Q9NUD5,Q8TB61,Q8WZA9,A1L0T0,Q8N128,P24390,P50897,Q96SK2,Q14534,Q9Y5L0,Q96CN7,Q9NY64,Q08722,Q5BKZ1,P51790,Q93050,P30519,O15460,P21964,Q3SXM5,O75312,P67809,Q92791,Q96L92,Q8N4Q0,Q96RQ1,Q9NRY5,P13674,Q14849,Q9BPZ3,P31751,Q8WTV0,Q92564,Q32P28,Q8N5M9,Q9NW15,Q92783,Q9Y487,Q969E2,Q9HD20,Q5KU26,Q01085,P11717,Q8IXH7,Q9HD45,O95070,O00400,O60499,P07602,P04066,O60831,Q8NBX0,Q5THJ4,Q9H2V7,O14976,Q12841,Q9UEE9,Q96D71
Localization
Protein Atlas Subcellular
protein_atlas_subcellular_location_all
128,3,129,5,6,135,8,267,388,263,394,15,144,271,272,411,279,408,275,276,282,27,28,398,287,163,293,171,44,306,49,180,312,55,308,185,194,68,69,198,330,334,212,89,217,94,349,351,350,100,103,361,236,109,110,238,365,114,254,375,370,371,124,127
263,236,628,2025,790,1051,370,1656,1859,696,2522,129,2711,672,398,2026,2139,109,135,1441,365,1245,6,2478,293,1886,2745,571,793,2140,2320,1248,361,1192,2763,2612,2593,238,2525,998,110,889,869,2843,1444,1626,476,1251,350,1089,55,1496,2672,978,663,979,2450,2213,1253,287,15,1533,957,921,2811,2673,418,28,194,1944,502,1168,2110,2926,2217,1140,1199,1027,5,1200,2603,1538,1666,1591,1258,1503,529,646,1367,144,282,723,1570,811,2401,2749,710,2663,445,834,2032,812,2844,1505,2927,2750,1002,1097,1506,1767,2218,1143,171,1119,1207,2058,351,1372,1099,1632,753,275,2094,371,2332,1058,2564,1510,631,2852,2184,1034,1548,945,1573,272,2889,1512,2512,308,2335,2359,2617,2880,2432,1406,1209,2618,596,690,1898,1775,198,163,2923,1839,276,987,2434,349,254,2038,1899,449,2909,1923,680,1286,2583,2760,1423,2255,843,1176,2311,1235,601,1877,100,2652,394,2469,49,330,651,2938,566,114,1084,2011,3,2902,2126,267,68,1743,2070,388,69,2677,1013,212,44,1481,27,217,1290,713,279,127,1269,1237,1519,1683,826,568,306,1745,705,180,271,625,1521,185,2314,1460,1238,668,1646,2947,1381,991,2493,1555,1293,375,731,1880,1609,94,103,499,2019,2550,128,2496,2761,457,559,312,1988,2770,8,334,408,1612,2414,1525,593,1932,124,1584,2370,1789,1388,1186,1297,735,2476,1017,1490,717,1019,1963,2477,89,2445,2637,411,582,828,2389,1302
1.3082387048731943,1.3860113542851535,0.5840797855852801,-0.45753228412024466,0.394648358795702,0.16273905820118395,0.9964874283803038,-0.22847370331607397,-0.34151131793657324,0.5061463962970855,-0.825148078218146,1.917270315417413,-1.0884248463707054,0.537486950272112,0.9399105014520449,-0.45753228412024466,-0.5366148538627052,2.06249462948218,1.894487649782089,-0.1001715700836958,1.0105173832723406,0.024485024344763594,3.558929341369213,-0.7827550573182713,1.202323609529759,-0.36063683389058815,-1.1567689963310013,0.6757985361220961,0.394648358795702,-0.5366148538627052,-0.6579670071768167,0.024485024344763594,1.0245022054180684,0.05945972020734923,-1.2029252754937023,-0.9329466915129715,-0.8895109457490417,1.3860113542851535,-0.825148078218146,0.1966311801772001,2.06249462948218,0.2967604582024043,0.31322807591179413,-1.4904417735103144,-0.1001715700836958,-0.20991366611478418,0.8245003681365923,0.024485024344763594,1.0523375857873305,0.12858251145984356,2.627845336521186,-0.1364482501831472,-1.0211206524758603,0.21347933237869962,0.5530732376857973,0.21347933237869962,-0.7617103122164987,-0.576695277069889,0.024485024344763594,1.2423453819314823,3.2622578968216644,-0.154699664595971,0.23026286775039087,0.2636380221709174,-1.3683690925791896,-1.0211206524758603,0.9113436498871638,3.058164653086549,1.5868275562513716,-0.3991392521076305,0.7804203434389911,0.07684293929142288,-0.5167106212981979,-2.6103707073970432,-0.576695277069889,0.09415745775210213,0.05945972020734923,0.17971792076718154,3.574391697694004,0.05945972020734923,-0.9111754241704362,-0.154699664595971,-0.22847370331607397,-0.19143174128541807,0.024485024344763594,-0.1364482501831472,0.7358896549563253,0.5686040539973861,-0.046312846762206455,1.8485582976056778,1.2556043625519968,0.4745792189320432,-0.17302728582659577,0.37848518872114384,-0.7199196503135434,-1.1567689963310013,0.4903913364797827,-0.9989116898321668,0.8825879960378804,0.3459784040561311,-0.45753228412024466,0.37848518872114384,-1.4904417735103144,-0.1364482501831472,-2.6423073304137117,-1.1567689963310013,0.1966311801772001,0.12858251145984356,-0.1364482501831472,-0.28462903979626186,-0.576695277069889,0.09415745775210213,1.6838460454736341,0.11140380677844741,0.05945972020734923,-0.4771701196736191,1.0523375857873305,-0.046312846762206455,0.12858251145984356,-0.20991366611478418,0.4427821773887004,1.2688229452074793,-0.4968959727005952,0.9964874283803038,-0.6579670071768167,0.16273905820118395,-0.8464982748968118,-0.1364482501831472,0.5840797855852801,-1.540227049969209,-0.5566094692716574,0.17971792076718154,-0.154699664595971,0.24698227118508845,-0.17302728582659577,1.2820013709130165,-1.7978838385941391,-0.1364482501831472,-0.8039006614231072,1.161929368281666,-0.6579670071768167,-0.6785213070020842,-0.9329466915129715,-1.6930219755579508,-0.7407654856874151,-0.06419237620988717,0.05945972020734923,-0.9329466915129715,0.6454394534643092,0.5218448013237352,-0.36063683389058815,-0.28462903979626186,1.574545797147203,1.7315509278111096,-2.484854757571256,-0.3224686466679636,1.2688229452074793,0.21347933237869962,-0.7407654856874151,1.06618870455087,1.3472994325027918,-0.45753228412024466,-0.36063683389058815,0.8825879960378804,-1.9875569410230292,-0.3798459053107705,0.537486950272112,0.00689245382919885,-0.8679522324143034,-1.1797869757098827,-0.08214508712671734,-0.596873097659703,0.3459784040561311,0.07684293929142288,-0.6375081142813843,0.04200726311648557,0.6301802761408241,-0.34151131793657324,2.1279058027565836,-0.9768137628162359,0.954123884167548,-0.7617103122164987,2.741891805558301,1.121155788951183,0.5686040539973861,-3.890341133320731,0.6908991641556643,2.018328951139827,0.1456940908786263,-0.43798169806465925,3.711080088907221,-1.9052771337681562,-0.5167106212981979,1.3082387048731943,2.4206641920055536,-0.26583072691689574,-0.4771701196736191,0.968290969875735,2.4004011679639556,-1.0211206524758603,0.1966311801772001,1.5126086522989541,2.8529812632786027,-0.11827242278503895,3.0842161304682922,1.4875835034045466,0.00689245382919885,0.4903913364797827,1.2688229452074793,1.9399333103611618,0.024485024344763594,0.04200726311648557,-0.1364482501831472,-0.22847370331607397,0.36226201680927644,0.6908991641556643,1.1754359209634744,-0.26583072691689574,0.5061463962970855,1.6597947156561212,1.2951398785464203,0.5995008148293052,-0.1364482501831472,1.6356088521917012,-0.6375081142813843,-0.1001715700836958,0.04200726311648557,0.5530732376857973,-0.20991366611478418,-11.275643989835725,-0.046312846762206455,0.21347933237869962,-0.7827550573182713,-0.154699664595971,0.00689245382919885,0.9964874283803038,0.4745792189320432,-0.34151131793657324,-0.19143174128541807,2.1816663680647275,2.1170726813344136,0.7951633152994793,-0.43798169806465925,-0.825148078218146,1.928616694517256,-0.7827550573182713,-1.1797869757098827,0.8681385994260129,0.7059476590359905,1.161929368281666,-0.41851760347793965,-1.2029252754937023,3.4886450034761873,1.121155788951183,0.9399105014520449,-0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2,948
Lysosome
15
45
2.754727
0.005874
O75503,P10619,P11717,Q8NCC3,O15118,Q14108,P04066,P07602,P50897,P54802,Q99523,Q15904,Q9Y487,Q93050,P53634
Processes and pathways
KEGG Pathways
msigdb_kegg
32,476,350,3,129,162,238,110,144,83,213,463,89,27,445
1992,2025,1618,657,129,1073,2139,32,707,238,708,998,110,2780,889,869,1626,476,890,1276,350,585,978,979,2926,144,445,83,1029,1768,2058,2094,1033,162,463,3,2677,27,213,1292,517,2167,1933,1358,89
-0.43798169806465925,-0.45753228412024466,-0.20991366611478418,0.5530732376857973,1.917270315417413,0.1456940908786263,-0.5366148538627052,3.040708346375522,0.4903913364797827,1.3860113542851535,0.4903913364797827,0.1966311801772001,2.06249462948218,-1.2495678211004613,0.2967604582024043,0.31322807591179413,-0.20991366611478418,0.8245003681365923,0.2967604582024043,0.00689245382919885,1.0523375857873305,0.660645419060983,0.21347933237869962,0.21347933237869962,-2.6103707073970432,1.8485582976056778,0.8825879960378804,2.2767750906766135,0.17971792076718154,-0.28462903979626186,-0.4771701196736191,-0.4968959727005952,0.17971792076718154,1.7315509278111096,0.8390951028692502,3.711080088907221,-1.0211206524758603,3.0842161304682922,1.5126086522989541,0.00689245382919885,0.7656273000310847,-0.5366148538627052,-0.3798459053107705,-0.028505915233174372,2.2347638458248005
2,948
Metalloprotease
16
39
2.743854
0.006072
P02786,O95630,P55786,P22695,O15372,Q96E52,Q7Z2K6,Q9NZ08,Q9UIQ6,P42892,Q99797,Q9BYT8,O75844,Q5JRX3,Q10713,O43847
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
442,192,2,477,292,229,432,105,12,16,374,186,121,59,447,189
2172,1694,292,189,1860,121,192,442,1793,2716,1395,477,2766,1338,16,1732,1204,2,447,2901,2806,59,2095,787,432,496,1125,880,2367,229,1984,1044,374,2802,186,1558,105,12,655
-0.5566094692716574,-0.24711250387957184,1.202323609529759,1.611286969212316,-0.34151131793657324,1.9624778628651733,1.5990745493593614,0.8825879960378804,-0.3035081182804855,-1.0884248463707054,-0.06419237620988717,0.8245003681365923,-1.2029252754937023,-0.028505915233174372,3.245617927748801,-0.26583072691689574,0.05945972020734923,3.711080088907221,0.8825879960378804,-1.9052771337681562,-1.344352687464858,2.5794159618228156,-0.4968959727005952,0.4107519613001489,0.8969895762705655,0.7951633152994793,0.11140380677844741,0.31322807591179413,-0.6785213070020842,1.4243805350193866,-0.41851760347793965,0.17971792076718154,0.9964874283803038,-1.32046570987856,1.6356088521917012,-0.154699664595971,2.095324359314597,3.368863420764839,0.5686040539973861
2,948
Organic acid transport
11
42
2.742522
0.006097
P31751,Q9H2D1,Q9UBX3,P08183,Q9Y619,P53985,Q96QD8,Q9BQT8,O43772,P09455,P30825
Processes and pathways
GO Biological process
msigdb_gobp
194,4,230,107,81,50,118,23,88,184,221
2928,88,441,365,888,641,2276,2834,1223,1307,2713,107,809,184,643,1396,242,1139,221,194,1944,722,1629,50,2844,1171,2650,1122,1284,1923,680,624,916,118,23,4,917,1385,804,230,1328,81
-2.8388595641615995,2.2347638458248005,0.8825879960378804,1.0105173832723406,0.2967604582024043,0.5686040539973861,-0.6171437624952562,-1.4412088289871978,0.04200726311648557,-0.010771004982313778,-1.0884248463707054,2.0844088865487853,0.37848518872114384,1.6356088521917012,0.5686040539973861,-0.06419237620988717,1.373145758933382,0.09415745775210213,1.4624128836284802,1.5868275562513716,-0.3991392521076305,0.4745792189320432,-0.20991366611478418,2.7136633954590907,-1.4904417735103144,0.07684293929142288,-0.9768137628162359,0.11140380677844741,0.00689245382919885,-0.3798459053107705,0.537486950272112,0.5995008148293052,0.2802305948711232,1.9960752529228047,3.118706149066854,3.666003780285035,0.2802305948711232,-0.046312846762206455,0.394648358795702,1.4243805350193866,-0.010771004982313778,2.3183799967279364
2,948
Steroid binding
7
20
2.736729
0.006205
O15118,Q14108,P45880,P21796,O15173,P35610,O00264
Functions
GO Molecular function
msigdb_gomf
129,162,71,111,80,178,92
92,129,80,1969,707,794,1163,111,1470,1664,2900,178,71,1768,162,308,625,1085,991,1483
2.1816663680647275,1.917270315417413,2.3183799967279364,-0.41851760347793965,0.4903913364797827,0.394648358795702,0.07684293929142288,2.0514955668887254,-0.11827242278503895,-0.22847370331607397,-1.8781849174669127,1.6597947156561212,2.369826344771198,-0.28462903979626186,1.7315509278111096,1.161929368281666,0.5995008148293052,0.1456940908786263,0.21347933237869962,-0.11827242278503895
2,948
Protein hydroxylation
7
13
2.712744
0.006673
Q32P28,Q92791,Q96AY3,Q9NWT6,O75718,P13674,O15460
Processes and pathways
GO Biological process
msigdb_gobp
198,44,534,376,21,55,398
398,21,526,55,1372,724,1172,198,44,534,1155,901,376
0.9399105014520449,3.1529198842609487,0.7358896549563253,2.627845336521186,-0.046312846762206455,0.4745792189320432,0.07684293929142288,1.574545797147203,2.8529812632786027,0.7358896549563253,0.09415745775210213,0.2967604582024043,0.9964874283803038
2,948
Metalloexopeptidase activity
10
20
2.712133
0.006685
P02786,P55786,Q9NQH7,Q7Z2K6,Q9NZ08,Q9UIQ6,P09960,P50579,O75976,O75844
Functions
GO Molecular function
msigdb_gomf
442,2,326,432,105,12,51,22,120,121
121,120,442,51,2716,2766,612,22,2,2095,432,515,1984,2548,1324,326,1557,1558,105,12
1.9624778628651733,1.9737061019075504,0.8825879960378804,2.694740627138941,-1.0884248463707054,-1.2029252754937023,0.6148675201656797,3.127285314223585,3.711080088907221,-0.4968959727005952,0.8969895762705655,0.7656273000310847,-0.41851760347793965,-0.825148078218146,-0.010771004982313778,1.1347895625307758,-0.154699664595971,-0.154699664595971,2.095324359314597,3.368863420764839
2,948
Positive regulation of rna splicing
7
23
2.7089
0.006751
Q14011,P62995,P38159,P98179,P26368,Q96E39,Q96QD8
Processes and pathways
GO Biological process
msigdb_gobp
99,228,130,102,239,211,118
293,1624,1251,1699,2643,239,2577,130,1542,228,102,1344,944,1403,631,99,728,211,1105,118,2132,2203,1020
1.202323609529759,-0.20991366611478418,0.024485024344763594,-0.24711250387957184,-0.9768137628162359,1.3860113542851535,-0.8679522324143034,1.917270315417413,-0.154699664595971,1.4243805350193866,2.1170726813344136,-0.028505915233174372,0.24698227118508845,-0.06419237620988717,0.5840797855852801,2.1279058027565836,0.4745792189320432,1.5250671893501497,0.12858251145984356,1.9960752529228047,-0.5167106212981979,-0.5566094692716574,0.1966311801772001
2,948
Glycoprotein metabolic process
27
56
2.701982
0.006893
O15118,Q9NQX7,Q86TM6,O60502,O60762,Q9BT22,Q6ZXV5,Q92542,Q9UKV5,Q9HC07,Q10472,P35610,Q8N4A0,Q08379,O43505,Q04656,Q96IZ0,Q96AA3,Q14697,Q9H4A6,Q7LGA3,Q9BS26,P33908,O60701,Q99805,Q8NCH0,Q8TCJ2
Processes and pathways
GO Biological process
msigdb_gobp
129,142,405,281,659,285,540,681,299,43,430,178,54,446,65,322,456,713,595,731,342,605,355,736,241,113,373
2025,790,129,1440,65,281,736,659,2895,1442,2447,2141,1250,1757,2175,355,1759,178,2243,893,2092,1703,1372,322,2405,446,739,430,1404,595,1454,540,342,843,405,54,2808,113,373,681,713,456,2865,241,605,285,1523,731,2632,43,142,1242,2519,299,1490,1819
-0.45753228412024466,0.394648358795702,1.917270315417413,-0.1001715700836958,2.4408320972461683,1.2556043625519968,0.4587096364267473,0.5530732376857973,-1.8512565808503108,-0.1001715700836958,-0.7617103122164987,-0.5366148538627052,0.024485024344763594,-0.28462903979626186,-0.5566094692716574,1.0384421790618117,-0.28462903979626186,1.6597947156561212,-0.596873097659703,0.2967604582024043,-0.4968959727005952,-0.24711250387957184,-0.046312846762206455,1.1347895625307758,-0.7199196503135434,0.8825879960378804,0.4587096364267473,0.8969895762705655,-0.06419237620988717,0.6454394534643092,-0.1001715700836958,0.7209443730522314,1.0937591810735925,0.3459784040561311,0.9399105014520449,2.65664263773781,-1.344352687464858,2.0294128700184095,0.9964874283803038,0.537486950272112,0.4903913364797827,0.8681385994260129,-1.5905769604580335,1.3860113542851535,0.6301802761408241,1.2556043625519968,-0.1364482501831472,0.4745792189320432,-0.9548257864570027,2.8712191617408704,1.8715840661178529,0.04200726311648557,-0.8039006614231072,1.188900583250081,-0.11827242278503895,-0.3035081182804855
2,948
er
28
84
2.686102
0.007229
Q969V3,Q07065,Q9NPA0,Q86TM6,Q99640,Q15392,Q86Y07,Q15006,P49755,Q16850,Q8N4V1,P61026,O75845,Q9NQC3,O15173,Q96N66,Q9Y5M8,O95470,Q9Y487,O00264,Q8NHH9,Q9P2W9,O00767,O96005,O00400,O60499,Q14739,Q8TCJ2
Localization
OpenCell Localization
opencell_localization
515,257,652,405,414,33,289,539,554,52,450,328,201,333,80,466,598,214,89,92,504,358,607,485,236,109,116,373
92,236,607,80,1491,1072,109,1442,1755,201,641,1995,214,485,2050,2640,1250,1757,1164,1531,2029,1863,2243,893,2805,1092,554,911,2604,1094,1733,2537,2302,1096,328,2092,1400,984,257,1770,2333,116,539,2650,1209,33,2541,1285,52,2006,1923,405,1842,289,450,2676,2224,727,504,373,2585,2158,1846,1810,515,756,1579,466,414,2160,991,1813,1106,1048,652,333,970,1961,358,950,1963,89,598,1301
2.1816663680647275,1.3860113542851535,0.6148675201656797,2.3183799967279364,-0.1364482501831472,0.1456940908786263,2.06249462948218,-0.1001715700836958,-0.28462903979626186,1.549877201936574,0.5686040539973861,-0.43798169806465925,1.5001141584399327,0.8098565473687283,-0.4771701196736191,-0.9768137628162359,0.024485024344763594,-0.28462903979626186,0.07684293929142288,-0.154699664595971,-0.45753228412024466,-0.34151131793657324,-0.596873097659703,0.2967604582024043,-1.344352687464858,0.12858251145984356,0.7059476590359905,0.2802305948711232,-0.9111754241704362,0.12858251145984356,-0.26583072691689574,-0.825148078218146,-0.6375081142813843,0.12858251145984356,1.121155788951183,-0.4968959727005952,-0.06419237620988717,0.21347933237869962,1.3343182502559603,-0.28462903979626186,-0.6579670071768167,2.007216460441714,0.7209443730522314,-0.9768137628162359,0.05945972020734923,2.9967531033007075,-0.825148078218146,0.00689245382919885,2.6852478237468818,-0.43798169806465925,-0.3798459053107705,0.9399105014520449,-0.3224686466679636,1.2423453819314823,0.8825879960378804,-1.0211206524758603,-0.576695277069889,0.4745792189320432,0.7804203434389911,0.9964874283803038,-0.8679522324143034,-0.5366148538627052,-0.3224686466679636,-0.3035081182804855,0.7656273000310847,0.4427821773887004,-0.17302728582659577,0.8390951028692502,0.925650523668678,-0.5366148538627052,0.21347933237869962,-0.3035081182804855,0.12858251145984356,0.17971792076718154,0.5686040539973861,1.121155788951183,0.23026286775039087,-0.3991392521076305,1.0384421790618117,0.24698227118508845,-0.3991392521076305,2.2347638458248005,0.6454394534643092,0.00689245382919885
2,948
Vesicle membrane
63
245
2.685685
0.007238
Q07065,O15118,P42785,Q9HD26,Q9NQX7,P62993,Q9UIQ6,P24390,P42892,Q9NY64,O43731,Q8N511,Q15043,Q08722,P51790,Q93050,P30519,Q9H270,Q14108,O43760,Q8IV08,Q9HC07,Q96L92,O60749,Q14849,Q6IAA8,O76024,Q8N4V1,Q8NHP6,P02786,Q8WTV0,Q04656,O15027,P61026,O00461,P01889,Q92783,Q99523,Q15904,Q9Y487,Q969E2,Q9UH99,Q5KU26,P04439,O00264,Q96JJ7,P11717,P10321,O43752,O60499,P07602,O60831,Q99805,O15400,P61923,P55899,Q9NP79,Q8TAD4,Q13555,Q9UBB6,O14964,O43924,Q9NZJ7
Localization
GO Cellular component
msigdb_gocc
257,129,5,524,142,393,12,15,16,408,19,149,404,275,282,27,28,415,162,417,166,43,306,48,308,449,313,450,319,442,68,322,200,328,76,339,212,213,463,89,217,484,349,348,92,481,350,475,360,109,110,365,241,237,367,115,499,117,249,507,501,380,517
2655,2273,2860,1992,92,628,76,1189,1618,1051,2928,501,200,129,2711,672,868,237,1221,1619,953,19,2139,360,417,1937,380,1305,109,2391,1586,48,1493,365,2275,1245,2478,1442,1886,1755,778,2745,2319,313,2320,1248,1914,1192,2763,2612,339,442,1223,348,1307,1827,110,1163,869,718,674,1626,475,1251,642,1276,350,1861,1112,764,1337,909,2213,2737,15,921,2280,2053,28,1312,2482,1339,1168,2243,798,5,16,1076,1258,646,554,1093,1541,1594,911,2604,282,723,2663,2645,2664,2032,2844,115,2782,1002,328,1097,2303,1029,2329,367,1703,393,2003,1143,1400,2058,1004,676,322,257,1835,275,2094,1978,754,2333,873,249,2814,1510,2004,2852,162,1573,1512,308,404,2617,1406,896,1209,690,2815,463,1036,349,2788,522,2038,449,2740,1423,2255,2311,601,166,450,149,1084,2068,727,319,117,878,68,2585,681,2677,1809,212,1846,27,217,1810,1268,2875,624,481,306,1380,1713,625,213,1521,241,899,2548,2440,1460,2947,1085,1292,992,901,1556,415,1325,43,524,1219,1048,499,2551,142,970,2919,2887,408,517,1015,2517,885,1856,507,2100,1525,593,484,12,1789,1933,671,1434,2679,2589,1751,735,1298,1018,1490,1019,1358,1244,1359,89,1188,2135,582,773,2553,1301,951,1302
-0.9989116898321668,-0.6171437624952562,-1.5905769604580335,-0.43798169806465925,2.1816663680647275,0.5840797855852801,2.339032470796956,0.05945972020734923,-0.20991366611478418,0.16273905820118395,-2.8388595641615995,0.7804203434389911,1.549877201936574,1.917270315417413,-1.0884248463707054,0.537486950272112,0.31322807591179413,1.3860113542851535,0.04200726311648557,-0.20991366611478418,0.23026286775039087,3.1953050908815848,-0.5366148538627052,1.0245022054180684,0.9113436498871638,-0.3991392521076305,0.9824120538036047,-0.010771004982313778,2.06249462948218,-0.7199196503135434,-0.19143174128541807,2.741891805558301,-0.1364482501831472,1.0105173832723406,-0.6171437624952562,0.024485024344763594,-0.7827550573182713,-0.1001715700836958,-0.36063683389058815,-0.28462903979626186,0.4107519613001489,-1.1567689963310013,-0.6579670071768167,1.1483806684923388,-0.6579670071768167,0.024485024344763594,-0.3798459053107705,0.05945972020734923,-1.2029252754937023,-0.9329466915129715,1.0937591810735925,0.8825879960378804,0.04200726311648557,1.06618870455087,-0.010771004982313778,-0.3224686466679636,2.06249462948218,0.07684293929142288,0.31322807591179413,0.4745792189320432,0.537486950272112,-0.20991366611478418,0.8245003681365923,0.024485024344763594,0.5686040539973861,0.00689245382919885,1.0523375857873305,-0.34151131793657324,0.11140380677844741,0.4267964258326052,-0.028505915233174372,0.2802305948711232,-0.576695277069889,-1.133870114754212,3.2622578968216644,0.2636380221709174,-0.6171437624952562,-0.4771701196736191,3.058164653086549,-0.010771004982313778,-0.7827550573182713,-0.028505915233174372,0.07684293929142288,-0.596873097659703,0.394648358795702,3.574391697694004,3.245617927748801,0.1456940908786263,0.024485024344763594,0.5686040539973861,0.7059476590359905,0.12858251145984356,-0.154699664595971,-0.19143174128541807,0.2802305948711232,-0.9111754241704362,1.2556043625519968,0.4745792189320432,-0.9989116898321668,-0.9768137628162359,-0.9989116898321668,-0.45753228412024466,-1.4904417735103144,2.007216460441714,-1.2495678211004613,0.1966311801772001,1.121155788951183,0.12858251145984356,-0.6375081142813843,0.17971792076718154,-0.6579670071768167,1.0105173832723406,-0.24711250387957184,0.954123884167548,-0.43798169806465925,0.09415745775210213,-0.06419237620988717,-0.4771701196736191,0.1966311801772001,0.537486950272112,1.1347895625307758,1.3343182502559603,-0.3224686466679636,1.2688229452074793,-0.4968959727005952,-0.41851760347793965,0.4427821773887004,-0.6579670071768167,0.31322807591179413,1.3602418598724249,-1.3683690925791896,-0.1364482501831472,-0.43798169806465925,-1.540227049969209,1.7315509278111096,-0.17302728582659577,-0.1364482501831472,1.161929368281666,0.9399105014520449,-0.9329466915129715,-0.06419237620988717,0.2967604582024043,0.05945972020734923,0.5218448013237352,-1.3683690925791896,0.8390951028692502,0.17971792076718154,1.06618870455087,-1.2730746077112312,0.7507838500099976,-0.45753228412024466,0.8825879960378804,-1.133870114754212,-0.08214508712671734,-0.596873097659703,-0.6375081142813843,0.6301802761408241,1.7077643034433876,0.8825879960378804,1.8137877280347836,0.1456940908786263,-0.4771701196736191,0.4745792189320432,1.1483806684923388,1.9960752529228047,0.31322807591179413,2.4206641920055536,-0.8679522324143034,0.537486950272112,-1.0211206524758603,-0.3035081182804855,1.5126086522989541,-0.3224686466679636,3.0842161304682922,1.4875835034045466,-0.3035081182804855,0.024485024344763594,-1.641504220074868,0.5995008148293052,0.8245003681365923,1.1754359209634744,-0.046312846762206455,-0.24711250387957184,0.5995008148293052,1.5126086522989541,-0.1364482501831472,1.3860113542851535,0.2967604582024043,-0.825148078218146,-0.7407654856874151,-0.1001715700836958,-11.275643989835725,0.1456940908786263,0.00689245382919885,0.21347933237869962,0.2967604582024043,-0.154699664595971,0.925650523668678,-0.010771004982313778,2.8712191617408704,0.7507838500099976,0.05945972020734923,0.17971792076718154,0.7951633152994793,-0.825148078218146,1.8715840661178529,0.23026286775039087,-2.332755838948225,-1.77143566283669,0.9399105014520449,0.7656273000310847,0.1966311801772001,-0.8039006614231072,0.31322807591179413,-0.3224686466679636,0.7804203434389911,-0.4968959727005952,-0.1364482501831472,0.660645419060983,0.8245003681365923,3.368863420764839,-0.28462903979626186,-0.3798459053107705,0.5530732376857973,-0.08214508712671734,-1.0211206524758603,-0.8679522324143034,-0.26583072691689574,0.4745792189320432,0.00689245382919885,0.1966311801772001,-0.11827242278503895,0.1966311801772001,-0.028505915233174372,0.04200726311648557,-0.028505915233174372,2.2347638458248005,0.07684293929142288,-0.5167106212981979,0.6757985361220961,0.4267964258326052,-0.825148078218146,0.00689245382919885,0.24698227118508845,0.00689245382919885
2,948
Protein insertion into membrane
15
30
2.671585
0.007549
Q9Y584,Q9NPA0,Q9Y512,Q15006,Q9Y5J7,Q9NS69,Q15070,Q9P0J0,O14737,Q9Y5J9,O60220,Q15629,P49069,Q8N4V1,Q9Y276
Processes and pathways
GO Biological process
msigdb_gobp
133,652,260,539,199,7,323,176,551,336,337,148,529,450,508
551,1073,1936,337,1443,1416,2352,2147,871,529,923,664,1006,539,323,148,1839,2006,450,2676,756,652,7,176,508,260,133,199,336,906
0.7059476590359905,0.1456940908786263,-0.3991392521076305,1.0937591810735925,-0.1001715700836958,-0.08214508712671734,-0.6785213070020842,-0.5366148538627052,0.31322807591179413,0.7358896549563253,0.2636380221709174,0.5530732376857973,0.1966311801772001,0.7209443730522314,1.1347895625307758,1.8137877280347836,-0.3224686466679636,-0.43798169806465925,0.8825879960378804,-1.0211206524758603,0.4427821773887004,0.5686040539973861,3.496511927362126,1.6718371053502799,0.7804203434389911,1.3343182502559603,1.917270315417413,1.574545797147203,1.1074790838974617,0.2967604582024043
2,948
Membrane protein complex
88
273
2.668121
0.007628
Q9NS69,O94901,O43676,Q9NVH1,Q93050,Q96S66,Q92643,P14406,Q15006,O96000,Q99595,P49755,O14925,O60749,Q9BUN8,Q16891,P00846,Q9Y5X3,P45880,Q9UBV8,P25054,Q9Y5M8,Q9NR28,Q9Y487,P20674,O60830,O60499,P21796,Q8N2K0,Q9Y4W6,Q9Y277,Q9Y584,Q9NPA0,P56385,P62072,P03886,Q8N511,Q9C0H2,Q6UXV4,O14949,P08754,P05026,O60716,Q92542,P0DP25,Q9UGP8,Q03519,Q9P0J0,P00403,Q15436,Q8N4H5,Q9BUR5,Q9Y5J7,Q96CU9,Q9Y6M9,O15400,Q13505,Q9Y512,Q9UDW1,Q07666,Q9UKV5,O75964,Q86Y39,O75431,P01889,P04439,P11717,Q9P2W9,P12236,O43752,P61923,Q8TCJ2,Q96ER9,P62993,Q86TM6,P06576,O43464,Q9H270,Q9NX63,O14920,Q6IAA8,Q8N4V1,P02786,Q15904,Q9UH99,P22695,P10321,Q9Y276
Localization
GO Cellular component
msigdb_gocc
7,519,24,549,27,545,542,34,539,36,42,554,552,48,53,564,60,582,71,593,586,598,87,89,610,106,109,111,636,655,654,133,652,648,664,145,149,150,666,151,661,660,658,681,674,168,676,176,174,690,182,183,199,210,220,237,244,260,274,288,299,302,309,338,339,348,350,358,362,360,367,373,397,393,405,402,400,415,436,424,449,450,442,463,484,477,475,508
2860,1992,1693,2024,1439,1189,1618,424,552,151,1491,1072,237,1221,1619,1722,400,953,24,2139,360,1305,109,658,48,106,2047,1968,1442,1755,338,778,1247,2319,1824,793,302,1443,1392,519,2320,1248,1659,2627,2602,1192,2763,2612,36,2238,174,60,339,442,145,348,1250,1757,794,660,749,1307,402,1827,809,2107,661,1394,869,2736,674,475,1362,2527,350,1564,362,688,34,1496,1363,1364,2091,2836,2395,610,1253,2765,111,870,2028,477,980,586,2377,2280,2823,2053,2578,1889,1338,1973,1759,1795,1339,1397,750,2217,2508,2243,2327,71,892,893,2793,2747,1258,1365,1202,554,2748,1169,1763,723,2178,2663,2645,2664,2032,812,2033,1867,1733,1118,766,648,2537,1055,2801,1029,923,2092,367,664,1206,393,1143,784,2058,676,288,1006,2248,1770,2221,2333,2564,244,873,2004,1573,1512,1283,539,2650,896,1082,690,463,1345,2289,564,947,1036,859,1839,1231,2006,860,449,666,405,309,2311,1347,636,182,450,149,2676,1084,1040,2068,1981,373,1808,2585,1236,681,2677,542,1983,27,845,866,210,1268,397,729,1380,545,1521,42,1216,881,2932,899,2587,1460,53,183,2947,150,1879,901,1556,415,1608,1354,1219,652,87,970,7,549,2887,1068,436,176,358,2100,1525,593,274,168,484,2167,1962,299,2679,1298,2134,1018,508,654,1019,1358,1220,1244,1359,89,655,260,133,199,1188,598,582,773,828,2553,1301,220
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2,948
Bulbar signs
10
13
2.621764
0.008748
P35637,P43243,Q9Y263,Q99720,P07602,P03886,P06753,Q15043,P00846,Q9NZJ7
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
98,452,359,467,110,145,618,404,60,517
1073,60,145,707,618,110,98,452,404,1013,467,517,359
0.1456940908786263,2.530433704556057,1.8369991927238165,0.4903913364797827,0.5995008148293052,2.06249462948218,2.1279058027565836,0.8681385994260129,0.9399105014520449,0.1966311801772001,0.8390951028692502,0.7656273000310847,1.0384421790618117
2,948
Regulation of defense response
19
76
2.615342
0.008914
Q9NUD5,P19174,Q08722,O43657,Q15233,Q96PK6,O14920,P60900,P53634,P23246,P43243,Q9UIV1,P01889,P28070,P04439,Q07021,P19474,Q9NZ08,O75844
Processes and pathways
GO Biological process
msigdb_gobp
8,264,275,31,165,297,424,315,445,444,452,472,339,86,348,226,97,105,121
424,31,2139,1022,907,2809,121,1443,1136,2448,339,707,1223,348,1416,2575,1726,1394,1276,891,1999,1309,264,97,444,2215,1114,1138,86,2378,1399,452,723,445,1340,315,1341,1976,1099,2771,226,1598,275,1058,873,1173,2308,165,1950,1264,1979,2723,926,840,1874,802,2096,636,1981,878,492,1983,2567,1178,297,1380,2865,898,1747,8,2898,105,1049,472,1298,581
0.8969895762705655,3.040708346375522,-0.5366148538627052,0.17971792076718154,0.2802305948711232,-1.3683690925791896,1.9624778628651733,-0.1001715700836958,0.09415745775210213,-0.7617103122164987,1.0937591810735925,0.4903913364797827,0.04200726311648557,1.06618870455087,-0.08214508712671734,-0.8679522324143034,-0.26583072691689574,-0.06419237620988717,0.00689245382919885,0.2967604582024043,-0.43798169806465925,-0.010771004982313778,1.3082387048731943,2.1279058027565836,0.8825879960378804,-0.576695277069889,0.11140380677844741,0.09415745775210213,2.266310677224161,-0.6991718914520957,-0.06419237620988717,0.8681385994260129,0.4745792189320432,0.8825879960378804,-0.028505915233174372,1.1483806684923388,-0.028505915233174372,-0.41851760347793965,0.12858251145984356,-1.2261851370906078,1.4370951229364066,-0.19143174128541807,1.2688229452074793,0.16273905820118395,0.31322807591179413,0.07684293929142288,-0.6375081142813843,1.7077643034433876,-0.3991392521076305,0.024485024344763594,-0.41851760347793965,-1.0884248463707054,0.2636380221709174,0.3459784040561311,-0.34151131793657324,0.394648358795702,-0.4968959727005952,0.5840797855852801,-0.41851760347793965,0.31322807591179413,0.8098565473687283,-0.41851760347793965,-0.8464982748968118,0.07684293929142288,1.188900583250081,-0.046312846762206455,-1.5905769604580335,0.2967604582024043,-0.26583072691689574,3.4886450034761873,-1.8512565808503108,2.095324359314597,0.17971792076718154,0.8390951028692502,0.00689245382919885,0.6757985361220961
2,948
Predicted secreted proteins
18
48
2.614731
0.00893
P02786,Q8WUJ1,P43490,Q92520,Q07021,O94919,Q15165,Q8N128,O60888,Q9UMX5,Q9BTY2,Q9HB40,Q9NZ08,O75718,Q9BUR5,Q12841,Q02818,P80303
Functions
Protein Atlas Protein class
protein_atlas_protein_class
442,161,224,291,226,473,134,394,39,73,357,141,105,21,183,371,126,30
39,21,1723,473,442,1223,2479,1827,1394,977,2628,643,1395,1532,2822,1114,224,1595,2645,1768,30,2943,574,126,226,488,371,1707,1401,134,2095,394,2902,161,1681,291,1429,742,2015,357,183,1324,2632,141,105,73,1490,2270
2.8893796757735113,3.1529198842609487,-0.26583072691689574,0.8245003681365923,0.8825879960378804,0.04200726311648557,-0.7827550573182713,-0.3224686466679636,-0.06419237620988717,0.21347933237869962,-0.9548257864570027,0.5686040539973861,-0.06419237620988717,-0.154699664595971,-1.392516309666817,0.11140380677844741,1.4370951229364066,-0.19143174128541807,-0.9768137628162359,-0.28462903979626186,3.0494454126243524,-4.622928371283897,0.6757985361220961,1.9399333103611618,1.4370951229364066,0.8098565473687283,0.9964874283803038,-0.24711250387957184,-0.06419237620988717,1.9058940189428801,-0.4968959727005952,0.954123884167548,-1.9052771337681562,1.7552073337708918,-0.22847370331607397,1.2157052518945781,-0.08214508712671734,0.4587096364267473,-0.43798169806465925,1.0384421790618117,1.6477186929262733,-0.010771004982313778,-0.9548257864570027,1.8715840661178529,2.095324359314597,2.369826344771198,-0.11827242278503895,-0.596873097659703
2,948
Lipid localization
18
69
2.613661
0.008958
Q6IAA8,P31751,O15118,Q14108,Q8WTV0,P23786,Q9H6V9,P08183,P07602,Q14534,P35610,Q9H2V7,Q14849,O43772,Q9BQE5,P09455,O43808,Q9BUR5
Processes and pathways
GO Biological process
msigdb_gobp
449,194,129,162,68,242,9,107,110,272,178,375,308,88,25,184,441,183
1071,2936,129,868,88,441,1586,1886,1192,2276,2050,2834,707,1223,1827,110,2780,2713,107,184,977,643,979,1470,1664,1532,242,1139,2900,194,1944,178,1503,722,1768,1207,1704,2771,162,272,308,1036,449,1923,1423,2311,2902,68,713,1579,625,467,25,2160,183,1085,991,2493,375,1483,1325,9,517,903,1584,734,1751,828,1301
0.1456940908786263,-3.6836870365757868,1.917270315417413,0.31322807591179413,2.2347638458248005,0.8825879960378804,-0.19143174128541807,-0.36063683389058815,0.05945972020734923,-0.6171437624952562,-0.4771701196736191,-1.4412088289871978,0.4903913364797827,0.04200726311648557,-0.3224686466679636,2.06249462948218,-1.2495678211004613,-1.0884248463707054,2.0844088865487853,1.6356088521917012,0.21347933237869962,0.5686040539973861,0.21347933237869962,-0.11827242278503895,-0.22847370331607397,-0.154699664595971,1.373145758933382,0.09415745775210213,-1.8781849174669127,1.5868275562513716,-0.3991392521076305,1.6597947156561212,-0.1364482501831472,0.4745792189320432,-0.28462903979626186,0.05945972020734923,-0.24711250387957184,-1.2261851370906078,1.7315509278111096,1.2820013709130165,1.161929368281666,0.17971792076718154,0.8825879960378804,-0.3798459053107705,-0.08214508712671734,-0.6375081142813843,-1.9052771337681562,2.4206641920055536,0.4903913364797827,-0.17302728582659577,0.5995008148293052,0.8390951028692502,3.1014959487367078,-0.5366148538627052,1.6477186929262733,0.1456940908786263,0.21347933237869962,-0.7827550573182713,0.9964874283803038,-0.11827242278503895,-0.010771004982313778,3.4490908825902338,0.7656273000310847,0.2967604582024043,-0.17302728582659577,0.4745792189320432,-0.26583072691689574,0.36226201680927644,0.00689245382919885
2,948
Mitochondrial fusion
10
15
2.611786
0.009007
Q9Y4W6,P02786,Q9H300,Q8N2A8,Q96E52,Q9NX63,O95140,Q8NAN2,O60313,Q99536
Processes and pathways
GO Biological process
msigdb_gobp
655,442,325,131,229,436,426,247,460,413
460,426,442,1006,1901,131,247,1457,229,413,325,436,734,655,975
0.8390951028692502,0.8969895762705655,0.8825879960378804,0.1966311801772001,-0.36063683389058815,1.917270315417413,1.373145758933382,-0.1001715700836958,1.4243805350193866,0.925650523668678,1.1347895625307758,0.8969895762705655,0.4745792189320432,0.5686040539973861,0.23026286775039087
2,948
Regulation of immune response
30
109
2.603305
0.009233
Q9NPR9,Q9NUD5,P49137,P19174,P23396,Q9NUQ9,Q08722,O43657,Q07666,Q15233,Q96PK6,O14920,P23246,P02786,P43243,Q96IZ0,Q9NR50,Q9NQC3,O96028,Q9UIV1,P01889,P28070,Q5KU26,P04439,Q07021,P19474,P09601,Q8WXF1,Q9NZ08,O15400
Processes and pathways
GO Biological process
msigdb_gobp
128,8,265,264,146,407,275,31,288,165,297,424,444,442,452,456,457,333,335,472,339,86,349,348,226,97,101,492,105,237
1992,694,424,237,1619,31,2139,1022,1885,2809,793,1443,2049,335,2448,339,442,1223,348,1416,2575,1726,1394,101,1444,2527,977,1276,891,1999,1566,1309,264,97,444,146,2215,1114,86,1534,1795,2378,1199,452,1200,2729,871,265,1366,2428,723,1095,1340,1341,1370,1206,1976,753,2771,226,288,1006,1598,275,2332,1546,1058,1173,1405,1573,2381,1080,2308,165,1264,2723,926,840,349,2874,2487,1456,1981,603,492,1983,2567,1781,2678,456,297,1925,2865,1216,1323,128,333,506,457,8,407,2898,105,1049,669,472,734,685,581
-0.43798169806465925,0.5061463962970855,0.8969895762705655,1.3860113542851535,-0.20991366611478418,3.040708346375522,-0.5366148538627052,0.17971792076718154,-0.36063683389058815,-1.3683690925791896,0.394648358795702,-0.1001715700836958,-0.4771701196736191,1.1074790838974617,-0.7617103122164987,1.0937591810735925,0.8825879960378804,0.04200726311648557,1.06618870455087,-0.08214508712671734,-0.8679522324143034,-0.26583072691689574,-0.06419237620988717,2.1170726813344136,-0.1001715700836958,-0.825148078218146,0.21347933237869962,0.00689245382919885,0.2967604582024043,-0.43798169806465925,-0.17302728582659577,-0.010771004982313778,1.3082387048731943,2.1279058027565836,0.8825879960378804,1.825409057538314,-0.576695277069889,0.11140380677844741,2.266310677224161,-0.154699664595971,-0.3035081182804855,-0.6991718914520957,0.05945972020734923,0.8681385994260129,0.05945972020734923,-1.1110891268052037,0.31322807591179413,1.3082387048731943,-0.046312846762206455,-0.7407654856874151,0.4745792189320432,0.12858251145984356,-0.028505915233174372,-0.028505915233174372,-0.046312846762206455,0.05945972020734923,-0.41851760347793965,0.4427821773887004,-1.2261851370906078,1.4370951229364066,1.2423453819314823,0.1966311801772001,-0.19143174128541807,1.2688229452074793,-0.6579670071768167,-0.154699664595971,0.16273905820118395,0.07684293929142288,-0.06419237620988717,-0.17302728582659577,-0.6991718914520957,0.1456940908786263,-0.6375081142813843,1.7077643034433876,0.024485024344763594,-1.0884248463707054,0.2636380221709174,0.3459784040561311,1.06618870455087,-1.641504220074868,-0.7827550573182713,-0.1001715700836958,-0.41851760347793965,0.6301802761408241,0.8098565473687283,-0.41851760347793965,-0.8464982748968118,-0.28462903979626186,-1.0211206524758603,0.8681385994260129,1.188900583250081,-0.3798459053107705,-1.5905769604580335,0.05945972020734923,-0.010771004982313778,1.928616694517256,1.121155788951183,0.7804203434389911,0.8681385994260129,3.4886450034761873,0.9399105014520449,-1.8512565808503108,2.095324359314597,0.17971792076718154,0.5530732376857973,0.8390951028692502,0.4745792189320432,0.537486950272112,0.6757985361220961
2,948
Establishment of protein localization to organelle
39
182
2.602976
0.009242
P55786,Q9Y584,Q9Y512,Q9NS69,Q8N1F7,Q9Y5L0,P46934,Q15629,Q5SRE5,O43464,Q9H270,Q14108,O75312,Q9UGP8,Q99595,Q9P0J0,P40855,O95140,Q8N4H5,O95831,Q5JRX3,Q10713,Q9H300,Q9Y5J7,Q15070,Q92973,P61026,Q9Y5J9,O60220,Q53FT3,Q92783,Q99523,P33908,O60830,Q99797,P52292,Q9Y276,Q5THJ4,O15397
Processes and pathways
GO Biological process
msigdb_gobp
2,133,260,7,395,411,20,148,277,400,415,162,293,168,42,176,427,426,182,57,59,447,325,199,323,455,328,336,337,208,212,213,355,106,374,503,508,254,379
627,850,1992,789,1993,1618,551,1858,552,501,379,400,791,1073,1936,337,2638,106,1938,293,2523,1191,1860,887,2601,1443,1939,426,818,2086,1393,57,2238,1249,2376,779,1416,1726,1164,674,2527,977,1251,642,1276,1445,1496,2211,2529,2506,2837,1396,2352,2900,1758,355,2147,1228,2282,1760,2424,1502,427,871,20,2150,646,1893,1202,2662,1367,1669,781,1368,1594,1094,503,2429,811,1542,752,2,1141,2537,2801,2302,328,923,982,2115,664,1896,1831,1948,738,1006,447,1079,2561,2059,162,1871,1081,2463,1283,1122,323,1082,148,1264,986,1898,926,947,208,1839,59,277,254,2909,963,2255,1876,1901,1516,395,182,815,1457,637,1267,212,1846,455,705,2546,1713,1606,213,827,1521,42,1216,374,899,882,1460,2441,1066,415,744,325,1354,2163,7,2132,806,176,2633,2444,1882,168,1788,2519,973,905,2370,1818,1434,807,1751,1413,508,1358,2103,260,133,199,336,411,906,598
0.5840797855852801,0.3296339066521189,-0.43798169806465925,0.394648358795702,-0.43798169806465925,-0.20991366611478418,0.7059476590359905,-0.34151131793657324,0.7059476590359905,0.7804203434389911,0.9824120538036047,0.9399105014520449,0.394648358795702,0.1456940908786263,-0.3991392521076305,1.0937591810735925,-0.9768137628162359,2.0844088865487853,-0.3991392521076305,1.202323609529759,-0.825148078218146,0.05945972020734923,-0.34151131793657324,0.2967604582024043,-0.9111754241704362,-0.1001715700836958,-0.3991392521076305,0.8969895762705655,0.36226201680927644,-0.4968959727005952,-0.06419237620988717,2.6085391476555078,-0.596873097659703,0.024485024344763594,-0.6991718914520957,0.4107519613001489,-0.08214508712671734,-0.26583072691689574,0.07684293929142288,0.537486950272112,-0.825148078218146,0.21347933237869962,0.024485024344763594,0.5686040539973861,0.00689245382919885,-0.1001715700836958,-0.1364482501831472,-0.576695277069889,-0.825148078218146,-0.8039006614231072,-1.4412088289871978,-0.06419237620988717,-0.6785213070020842,-1.8781849174669127,-0.28462903979626186,1.0384421790618117,-0.5366148538627052,0.04200726311648557,-0.6171437624952562,-0.28462903979626186,-0.7407654856874151,-0.1364482501831472,0.8969895762705655,0.31322807591179413,3.178401473028381,-0.5366148538627052,0.5686040539973861,-0.36063683389058815,0.05945972020734923,-0.9989116898321668,-0.046312846762206455,-0.22847370331607397,0.4107519613001489,-0.046312846762206455,-0.19143174128541807,0.12858251145984356,0.7804203434389911,-0.7407654856874151,0.37848518872114384,-0.154699664595971,0.4427821773887004,3.711080088907221,0.09415745775210213,-0.825148078218146,-1.32046570987856,-0.6375081142813843,1.121155788951183,0.2636380221709174,0.21347933237869962,-0.5167106212981979,0.5530732376857973,-0.36063683389058815,-0.3224686466679636,-0.3991392521076305,0.4587096364267473,0.1966311801772001,0.8825879960378804,0.1456940908786263,-0.8464982748968118,-0.4771701196736191,1.7315509278111096,-0.34151131793657324,0.1456940908786263,-0.7617103122164987,0.00689245382919885,0.11140380677844741,1.1347895625307758,0.1456940908786263,1.8137877280347836,0.024485024344763594,0.21347933237869962,-0.36063683389058815,0.2636380221709174,0.24698227118508845,1.5250671893501497,-0.3224686466679636,2.5794159618228156,1.2688229452074793,1.3472994325027918,-1.9875569410230292,0.23026286775039087,-0.596873097659703,-0.34151131793657324,-0.36063683389058815,-0.1364482501831472,0.954123884167548,1.6477186929262733,0.37848518872114384,-0.1001715700836958,0.5840797855852801,0.024485024344763594,1.5126086522989541,-0.3224686466679636,0.8681385994260129,0.5061463962970855,-0.825148078218146,-0.24711250387957184,-0.19143174128541807,1.5126086522989541,0.36226201680927644,-0.1364482501831472,2.8712191617408704,0.05945972020734923,0.9964874283803038,0.2967604582024043,0.31322807591179413,-0.1001715700836958,-0.7407654856874151,0.16273905820118395,0.925650523668678,0.4587096364267473,1.1347895625307758,-0.028505915233174372,-0.5366148538627052,3.496511927362126,-0.5167106212981979,0.394648358795702,1.6718371053502799,-0.9548257864570027,-0.7407654856874151,-0.34151131793657324,1.7077643034433876,-0.28462903979626186,-0.8039006614231072,0.23026286775039087,0.2967604582024043,-0.6785213070020842,-0.3035081182804855,-0.08214508712671734,0.394648358795702,-0.26583072691689574,-0.06419237620988717,0.7804203434389911,-0.028505915233174372,-0.4968959727005952,1.3343182502559603,1.917270315417413,1.574545797147203,1.1074790838974617,0.9399105014520449,0.2967604582024043,0.6454394534643092
2,948
Regulation of blood pressure
6
17
2.596515
0.009417
P42785,P09601,Q9NZ08,Q9HB40,Q9UIQ6,P42892
Processes and pathways
GO Biological process
msigdb_gobp
5,101,105,141,12,16
2319,2420,794,286,101,2863,1112,5,16,1669,1920,2329,2095,141,105,12,582
-0.6579670071768167,-0.7407654856874151,0.394648358795702,1.2423453819314823,2.1170726813344136,-1.5905769604580335,0.11140380677844741,3.574391697694004,3.245617927748801,-0.22847370331607397,-0.3798459053107705,-0.6579670071768167,-0.4968959727005952,1.8715840661178529,2.095324359314597,3.368863420764839,0.6757985361220961
2,948
Abnormal muscle fiber morphology
23
67
2.590537
0.009583
P51114,Q9H2D1,P13807,P61978,P31483,Q9Y5L0,P03886,Q70HW3,O43676,P09651,P00403,O95831,P00846,P43243,P50402,O14979,Q99720,O60313,P35637,P22626,Q8NI60,P23786,Q9Y276
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
256,4,521,139,392,411,145,18,24,294,174,57,60,452,197,70,467,460,98,227,497,242,508
2024,2928,70,24,2658,460,1442,57,2238,174,60,1249,145,2857,618,2714,294,2628,1564,521,2737,227,242,1889,392,98,2426,452,1666,197,1093,256,1629,1866,1733,139,1372,2405,2565,2693,2675,2540,1951,18,2760,634,600,532,1980,497,1982,1236,1713,467,2587,2752,2827,883,1522,4,2632,2019,508,2387,655,411,1819
-0.45753228412024466,-2.8388595641615995,2.3800421400870855,3.1101097166990783,-0.9989116898321668,0.8390951028692502,-0.1001715700836958,2.6085391476555078,-0.596873097659703,1.6718371053502799,2.530433704556057,0.024485024344763594,1.8369991927238165,-1.5653306411594137,0.5995008148293052,-1.0884248463707054,1.202323609529759,-0.9548257864570027,-0.17302728582659577,0.7507838500099976,-1.133870114754212,1.4243805350193866,1.373145758933382,-0.36063683389058815,0.954123884167548,2.1279058027565836,-0.7407654856874151,0.8681385994260129,-0.22847370331607397,1.574545797147203,0.12858251145984356,1.3343182502559603,-0.20991366611478418,-0.34151131793657324,-0.26583072691689574,1.8715840661178529,-0.046312846762206455,-0.7199196503135434,-0.8464982748968118,-1.0434417517569528,-1.0211206524758603,-0.825148078218146,-0.3991392521076305,3.2289128066153725,-1.1797869757098827,0.5840797855852801,0.6301802761408241,0.7358896549563253,-0.41851760347793965,0.7951633152994793,-0.41851760347793965,0.04200726311648557,-0.24711250387957184,0.8390951028692502,-0.8679522324143034,-1.1567689963310013,-1.392516309666817,0.31322807591179413,-0.1364482501831472,3.666003780285035,-0.9548257864570027,-0.43798169806465925,0.7804203434389911,-0.6991718914520957,0.5686040539973861,0.9399105014520449,-0.3035081182804855
2,948
Amyotrophic lateral sclerosis
8
15
2.590456
0.009585
P35637,P22626,P43243,Q15165,P09651,Q92804,P31483,Q99720
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
98,227,452,134,294,204,392,467
1995,1275,294,227,392,98,452,512,1733,2561,985,134,204,467,1018
-0.43798169806465925,0.00689245382919885,1.202323609529759,1.4243805350193866,0.954123884167548,2.1279058027565836,0.8681385994260129,0.7656273000310847,-0.26583072691689574,-0.8464982748968118,0.21347933237869962,1.9058940189428801,1.537489972244893,0.8390951028692502,0.1966311801772001
2,948
Secretory granule membrane
18
64
2.584611
0.009749
Q07065,Q6IAA8,P11717,P10321,P42785,P61026,Q5T9A4,Q9NQX7,P07602,P01889,Q8TAD4,Q08722,O00264,Q93050,P30519,Q96JJ7,Q8NHP6,Q9NZJ7
Localization
GO Cellular component
msigdb_gocc
257,449,350,475,5,328,522,142,110,339,117,275,92,27,28,481,319,517
2860,92,2711,868,2391,2275,2478,2745,2319,2320,339,110,1626,475,1276,350,1861,764,921,28,1312,2482,1168,2243,5,1076,554,1541,1594,723,2663,1002,328,1097,2303,2329,2003,1400,257,1835,275,1978,1510,1573,1209,1036,2788,522,449,727,319,117,681,27,1810,481,2548,1292,1048,142,517,1019,1188,951
-1.5905769604580335,2.1816663680647275,-1.0884248463707054,0.31322807591179413,-0.7199196503135434,-0.6171437624952562,-0.7827550573182713,-1.1567689963310013,-0.6579670071768167,-0.6579670071768167,1.0937591810735925,2.06249462948218,-0.20991366611478418,0.8245003681365923,0.00689245382919885,1.0523375857873305,-0.34151131793657324,0.4267964258326052,0.2636380221709174,3.058164653086549,-0.010771004982313778,-0.7827550573182713,0.07684293929142288,-0.596873097659703,3.574391697694004,0.1456940908786263,0.7059476590359905,-0.154699664595971,-0.19143174128541807,0.4745792189320432,-0.9989116898321668,0.1966311801772001,1.121155788951183,0.12858251145984356,-0.6375081142813843,-0.6579670071768167,-0.43798169806465925,-0.06419237620988717,1.3343182502559603,-0.3224686466679636,1.2688229452074793,-0.41851760347793965,-0.1364482501831472,-0.17302728582659577,0.05945972020734923,0.17971792076718154,-1.2730746077112312,0.7507838500099976,0.8825879960378804,0.4745792189320432,1.1483806684923388,1.9960752529228047,0.537486950272112,3.0842161304682922,-0.3035081182804855,0.8245003681365923,-0.825148078218146,0.00689245382919885,0.17971792076718154,1.8715840661178529,0.7656273000310847,0.1966311801772001,0.07684293929142288,0.24698227118508845
2,948
EF-hand domain [IPR002048]
18
43
2.583791
0.009772
Q03001,Q9NWM8,Q02818,P0DP25,Q14257,P19174,Q9UBV8,O43852,Q66K14,Q15293,Q96AY3,Q9UM19,Q12841,P14649,Q9Y680,Q96D71,P80303,O95202
Sequence
InterPro Domain
interpro_domain
421,187,126,674,41,264,593,74,203,621,534,215,371,662,90,127,30,697
1304,74,1442,888,697,1467,1916,674,1277,2876,2175,662,2810,264,1312,999,799,1630,30,126,421,371,1034,41,2616,621,203,927,1711,1424,1347,727,534,127,2587,992,1325,187,593,1328,215,2266,90
-0.010771004982313778,2.3493216246615503,-0.1001715700836958,0.2967604582024043,0.5061463962970855,-0.11827242278503895,-0.3798459053107705,0.537486950272112,0.00689245382919885,-1.6671884467700155,-0.5566094692716574,0.5530732376857973,-1.3683690925791896,1.3082387048731943,-0.010771004982313778,0.1966311801772001,0.394648358795702,-0.20991366611478418,3.0494454126243524,1.9399333103611618,0.9113436498871638,0.9964874283803038,0.17971792076718154,2.8712191617408704,-0.9329466915129715,0.5995008148293052,1.549877201936574,0.2636380221709174,-0.24711250387957184,-0.08214508712671734,-0.028505915233174372,0.4745792189320432,0.7358896549563253,1.9399333103611618,-0.8679522324143034,0.21347933237869962,-0.010771004982313778,1.6356088521917012,0.660645419060983,-0.010771004982313778,1.5001141584399327,-0.596873097659703,2.2136033965250372
2,948
Establishment of protein localization to mitochondrial membrane
11
20
2.583174
0.00979
Q9Y584,Q9Y512,Q9Y5J7,Q15070,Q9NS69,Q9P0J0,O14737,P62072,Q9Y5J9,O60220,Q9Y276
Processes and pathways
GO Biological process
msigdb_gobp
133,260,199,323,7,176,551,664,336,337,508
1992,551,337,1443,1416,674,2352,2147,664,1006,323,1839,7,176,508,260,133,199,336,906
-0.43798169806465925,0.7059476590359905,1.0937591810735925,-0.1001715700836958,-0.08214508712671734,0.537486950272112,-0.6785213070020842,-0.5366148538627052,0.5530732376857973,0.1966311801772001,1.1347895625307758,-0.3224686466679636,3.496511927362126,1.6718371053502799,0.7804203434389911,1.3343182502559603,1.917270315417413,1.574545797147203,1.1074790838974617,0.2967604582024043
2,948
Respirasome
12
43
2.582453
0.00981
P14406,O96000,Q9P0J0,P00403,P03886,Q9UDW1,Q96CU9,O14949,Q6DKK2,Q9Y6M9,O43676,Q13423
Localization
GO Cellular component
msigdb_gocc
34,36,176,174,145,274,210,151,152,220,24,216
2024,1439,151,24,2047,1968,1247,1659,2627,2602,36,174,145,2107,2736,1362,688,34,1363,1364,2395,610,870,477,2823,1889,1338,2793,2748,2178,216,1345,2289,152,431,309,210,1068,176,274,508,1220,220
-0.45753228412024466,-0.1001715700836958,1.8021350389030668,3.1101097166990783,-0.4771701196736191,-0.41851760347793965,0.024485024344763594,-0.22847370331607397,-0.9548257864570027,-0.9111754241704362,2.943403293840926,1.6718371053502799,1.8369991927238165,-0.5167106212981979,-1.133870114754212,-0.046312846762206455,0.5218448013237352,2.9879075612027455,-0.046312846762206455,-0.046312846762206455,-0.7199196503135434,0.6148675201656797,0.31322807591179413,0.8245003681365923,-1.392516309666817,-0.36063683389058815,-0.028505915233174372,-1.2967067971056643,-1.1567689963310013,-0.5566094692716574,1.4875835034045466,-0.028505915233174372,-0.6171437624952562,1.8021350389030668,0.8969895762705655,1.161929368281666,1.5250671893501497,0.16273905820118395,1.6718371053502799,1.2820013709130165,0.7804203434389911,0.05945972020734923,1.4750164810877993
2,948
Protein transporter activity
6
15
2.573755
0.01006
Q9Y584,Q9NS69,Q9UGP8,Q99595,O60830,Q9HD20
Functions
GO Molecular function
msigdb_gomf
133,7,168,42,106,94
552,106,1443,2238,554,923,2772,1082,876,42,94,7,168,133,336
0.7059476590359905,2.0844088865487853,-0.1001715700836958,-0.596873097659703,0.7059476590359905,0.2636380221709174,-1.2261851370906078,0.1456940908786263,0.31322807591179413,2.8712191617408704,2.1816663680647275,3.496511927362126,1.7077643034433876,1.917270315417413,1.1074790838974617
2,948
Transition metal ion transport
9
16
2.567015
0.010258
P02786,Q04656,Q9HC07,O15173,O75027,Q15043,Q8TAD4,Q8N4V1,Q9HD20
Processes and pathways
GO Biological process
msigdb_gobp
442,322,43,80,425,404,117,450,94
80,425,442,538,1093,2883,2058,1314,322,404,450,117,1522,804,43,94
2.3183799967279364,0.8969895762705655,0.8825879960378804,0.7209443730522314,0.12858251145984356,-1.7451438249828646,-0.4771701196736191,-0.010771004982313778,1.1347895625307758,0.9399105014520449,0.8825879960378804,1.9960752529228047,-0.1364482501831472,0.394648358795702,2.8712191617408704,2.1816663680647275
2,948
Abnormal social behavior
17
62
2.556119
0.010585
Q15067,Q15056,O96000,Q15233,Q9NPL8,Q9P0J0,P07602,Q8IUX1,P03886,Q96CU9,Q9Y6M9,Q86Y39,O43676,O43464,Q5KU26,Q9UHX1,Q9NZJ7
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
193,422,36,165,505,176,110,273,145,210,220,309,24,400,349,61,517
400,24,1073,1528,2047,1968,1247,888,36,2238,145,110,1563,630,2395,1396,2685,2823,2281,1279,2748,1920,1629,1799,1949,924,530,739,1402,2062,422,193,165,2121,1454,349,860,309,273,2622,2471,210,1268,2312,1214,1215,2865,1555,1714,505,2496,1068,517,1854,176,61,2133,1962,1220,1131,2270,220
0.9399105014520449,3.1101097166990783,0.1456940908786263,-0.154699664595971,-0.4771701196736191,-0.41851760347793965,0.024485024344763594,0.2967604582024043,2.943403293840926,-0.596873097659703,1.8369991927238165,2.06249462948218,-0.17302728582659577,0.5840797855852801,-0.7199196503135434,-0.06419237620988717,-1.0434417517569528,-1.392516309666817,-0.6171437624952562,0.00689245382919885,-1.1567689963310013,-0.3798459053107705,-0.20991366611478418,-0.3035081182804855,-0.3991392521076305,0.2636380221709174,0.7358896549563253,0.4587096364267473,-0.06419237620988717,-0.4771701196736191,0.9113436498871638,1.5990745493593614,1.7077643034433876,-0.5167106212981979,-0.1001715700836958,1.06618870455087,0.3296339066521189,1.161929368281666,1.2820013709130165,-0.9329466915129715,-0.7617103122164987,1.5250671893501497,0.024485024344763594,-0.6375081142813843,0.05945972020734923,0.05945972020734923,-1.5905769604580335,-0.154699664595971,-0.24711250387957184,0.7804203434389911,-0.7827550573182713,0.16273905820118395,0.7656273000310847,-0.3224686466679636,1.6718371053502799,2.530433704556057,-0.5167106212981979,-0.3991392521076305,0.05945972020734923,0.11140380677844741,-0.596873097659703,1.4750164810877993
2,948
Endosomal transport
16
67
2.554596
0.010631
O75503,Q92538,Q8NBN3,P61026,O43752,O60499,Q96L92,O60749,Q9NP79,Q4J6C6,Q92783,Q99523,Q15904,Q6IAA8,O14964,Q96D71
Processes and pathways
GO Biological process
msigdb_gobp
32,541,35,328,360,109,306,48,499,82,212,213,463,449,501,127
1992,1618,501,868,1221,953,360,747,1305,109,48,1441,1886,778,32,1198,646,1594,911,2604,2749,1733,2782,328,1097,2058,2333,2564,2004,1871,985,2617,463,82,2038,449,2255,1235,1516,35,2585,541,212,1041,127,306,1380,213,1460,1956,1181,992,1556,1325,1219,499,1015,1856,1525,1584,2679,1751,1298,1018,1359,2135,582
-0.43798169806465925,-0.20991366611478418,0.7804203434389911,0.31322807591179413,0.04200726311648557,0.23026286775039087,1.0245022054180684,0.4427821773887004,-0.010771004982313778,2.06249462948218,2.741891805558301,-0.1001715700836958,-0.36063683389058815,0.4107519613001489,3.040708346375522,0.05945972020734923,0.5686040539973861,-0.19143174128541807,0.2802305948711232,-0.9111754241704362,-1.1567689963310013,-0.26583072691689574,-1.2495678211004613,1.121155788951183,0.12858251145984356,-0.4771701196736191,-0.6579670071768167,-0.8464982748968118,-0.43798169806465925,-0.34151131793657324,0.21347933237869962,-0.9329466915129715,0.8390951028692502,2.2976278530369267,-0.45753228412024466,0.8825879960378804,-0.596873097659703,0.04200726311648557,-0.1364482501831472,2.9790436821717172,-0.8679522324143034,0.7209443730522314,1.5126086522989541,0.17971792076718154,1.9399333103611618,1.1754359209634744,-0.046312846762206455,1.5126086522989541,-0.1001715700836958,-0.3991392521076305,0.07684293929142288,0.21347933237869962,-0.154699664595971,-0.010771004982313778,0.05945972020734923,0.7951633152994793,0.1966311801772001,-0.3224686466679636,-0.1364482501831472,-0.17302728582659577,-1.0211206524758603,-0.26583072691689574,0.00689245382919885,0.1966311801772001,-0.028505915233174372,-0.5167106212981979,0.6757985361220961
2,948
Carbohydrate derivative transport
7
15
2.549728
0.010781
Q8WTV0,Q8TB61,P12236,O00400,P07602,Q08722,O43808
Processes and pathways
GO Biological process
msigdb_gobp
68,267,362,236,110,275,441
1134,236,441,749,110,1564,362,1768,275,927,267,68,713,934,517
0.09415745775210213,1.3860113542851535,0.8825879960378804,0.4427821773887004,2.06249462948218,-0.17302728582659577,1.0245022054180684,-0.28462903979626186,1.2688229452074793,0.2636380221709174,1.3082387048731943,2.4206641920055536,0.4903913364797827,0.2636380221709174,0.7656273000310847
2,948
Sphingolipid metabolic process
12
26
2.548315
0.010824
Q9NZ01,Q8NCC3,Q96G23,P06280,P30153,P07602,P50897,Q99805,P27544,O95470,O43464,Q9NZJ7
Processes and pathways
GO Biological process
msigdb_gobp
653,3,72,708,587,110,144,241,303,214,400,517
1491,1072,400,214,707,708,998,110,2780,978,979,1470,303,587,144,1006,1033,1839,3,72,241,1880,1611,653,517,848
-0.1364482501831472,0.1456940908786263,0.9399105014520449,1.5001141584399327,0.4903913364797827,0.4903913364797827,0.1966311801772001,2.06249462948218,-1.2495678211004613,0.21347933237869962,0.21347933237869962,-0.11827242278503895,1.1754359209634744,0.660645419060983,1.8485582976056778,0.1966311801772001,0.17971792076718154,-0.3224686466679636,3.711080088907221,2.369826344771198,1.3860113542851535,-0.34151131793657324,-0.19143174128541807,0.5686040539973861,0.7656273000310847,0.3459784040561311
2,948
Activation of immune response
14
45
2.543536
0.010974
Q07666,Q07021,P43243,Q15233,Q9NUD5,Q96IZ0,P19174,Q9NR50,Q96PK6,P23396,O14920,Q08722,P04439,P23246
Processes and pathways
GO Biological process
msigdb_gobp
288,226,452,165,8,456,264,457,297,146,424,275,348,444
424,1022,1443,2049,2448,348,1416,2575,1394,977,891,1999,1566,264,444,146,1534,1795,1199,452,2729,871,1366,2428,1370,1976,753,226,288,1006,275,1546,1058,1405,165,2723,492,456,297,1216,457,8,1049,669,734
0.8969895762705655,0.17971792076718154,-0.1001715700836958,-0.4771701196736191,-0.7617103122164987,1.06618870455087,-0.08214508712671734,-0.8679522324143034,-0.06419237620988717,0.21347933237869962,0.2967604582024043,-0.43798169806465925,-0.17302728582659577,1.3082387048731943,0.8825879960378804,1.825409057538314,-0.154699664595971,-0.3035081182804855,0.05945972020734923,0.8681385994260129,-1.1110891268052037,0.31322807591179413,-0.046312846762206455,-0.7407654856874151,-0.046312846762206455,-0.41851760347793965,0.4427821773887004,1.4370951229364066,1.2423453819314823,0.1966311801772001,1.2688229452074793,-0.154699664595971,0.16273905820118395,-0.06419237620988717,1.7077643034433876,-1.0884248463707054,0.8098565473687283,0.8681385994260129,1.188900583250081,0.05945972020734923,0.8681385994260129,3.4886450034761873,0.17971792076718154,0.5530732376857973,0.4745792189320432
2,948
Outer mitochondrial membrane protein complex
9
16
2.529068
0.011437
Q9Y512,Q9NS69,Q9NX63,O75431,Q13505,Q8N4H5,Q16891,Q9NVH1,Q9BUR5
Localization
GO Cellular component
msigdb_gocc
260,7,436,338,244,182,564,549,183
338,1443,2238,2508,244,1082,564,1231,860,666,182,183,7,549,436,260
1.0937591810735925,-0.1001715700836958,-0.596873097659703,-0.8039006614231072,1.373145758933382,0.1456940908786263,0.6908991641556643,0.04200726311648557,0.3296339066521189,0.5530732376857973,1.6477186929262733,1.6477186929262733,3.496511927362126,0.7209443730522314,0.8969895762705655,1.3343182502559603
2,948
Cholesterol metabolism with bloch and kandutschrussell pathways
10
24
2.526765
0.011512
Q15392,P04035,O75845,Q14534,P35610,Q15800,Q16850,Q14739,O95864,P37268
Processes and pathways
WikiPathways
msigdb_wp
33,261,201,272,178,246,52,116,26,223
607,2683,201,2276,26,261,528,1944,178,223,2805,1365,2246,1099,2704,272,116,2722,33,2541,246,52,332,1787
0.6148675201656797,-1.0434417517569528,1.549877201936574,-0.6171437624952562,3.0842161304682922,1.3212980845713802,0.7358896549563253,-0.3991392521076305,1.6597947156561212,1.449772501389248,-1.344352687464858,-0.046312846762206455,-0.596873097659703,0.12858251145984356,-1.065876105040331,1.2820013709130165,2.007216460441714,-1.0884248463707054,2.9967531033007075,-0.825148078218146,1.373145758933382,2.6852478237468818,1.121155788951183,-0.28462903979626186
2,948
Protein maturation
18
70
2.523884
0.011607
O75503,Q15392,Q9H300,O75844,Q9NQH7,Q96E52,O76024,Q92896,Q14CX7,P42892,Q99797,Q9BXJ9,P50579,Q8TAD4,Q86UY6,O43464,Q5JRX3,O75976
Processes and pathways
GO Biological process
msigdb_gobp
32,33,325,121,326,229,313,91,235,16,374,311,22,117,56,400,59,120
850,1440,2832,400,1860,32,2319,121,120,2872,313,1914,1622,2419,2735,1827,2504,2527,2810,2422,2280,1280,538,2327,16,613,1730,22,1055,2801,1206,784,739,447,724,1172,235,1283,33,59,1407,822,2598,56,2914,2068,117,1808,681,91,229,567,1155,2230,1044,374,2548,557,1218,311,2386,325,1985,2632,326,1067,706,734,2345,655
0.3296339066521189,-0.1001715700836958,-1.4412088289871978,0.9399105014520449,-0.34151131793657324,3.040708346375522,-0.6579670071768167,1.9624778628651733,1.9737061019075504,-1.641504220074868,1.1483806684923388,-0.3798459053107705,-0.20991366611478418,-0.7407654856874151,-1.133870114754212,-0.3224686466679636,-0.8039006614231072,-0.825148078218146,-1.3683690925791896,-0.7407654856874151,-0.6171437624952562,0.00689245382919885,0.7209443730522314,-0.6579670071768167,3.245617927748801,0.6148675201656797,-0.26583072691689574,3.127285314223585,0.16273905820118395,-1.32046570987856,0.05945972020734923,0.4107519613001489,0.4587096364267473,0.8825879960378804,0.4745792189320432,0.07684293929142288,1.3988388685809194,0.00689245382919885,2.9967531033007075,2.5794159618228156,-0.06419237620988717,0.36226201680927644,-0.8895109457490417,2.627845336521186,-2.0996813597026103,-0.4771701196736191,1.9960752529228047,-0.3035081182804855,0.537486950272112,2.202984027932319,1.4243805350193866,0.6908991641556643,0.09415745775210213,-0.576695277069889,0.17971792076718154,0.9964874283803038,-0.825148078218146,0.7059476590359905,0.05945972020734923,1.161929368281666,-0.6991718914520957,1.1347895625307758,-0.41851760347793965,-0.9548257864570027,1.1347895625307758,0.16273905820118395,0.5061463962970855,0.4745792189320432,-0.6579670071768167,0.5686040539973861
2,948
Regulation of alternative mrna splicing via spliceosome
10
25
2.519482
0.011753
P51114,Q07666,P51116,P62995,P38159,P09651,P31483,Q9BWF3,P98175,Q9UHX1
Processes and pathways
GO Biological process
msigdb_gobp
256,288,420,228,130,294,392,280,382,61
2206,294,1469,833,1862,392,130,2399,256,420,765,228,382,1675,530,288,1478,1775,712,1520,280,1852,61,1020,996
-0.576695277069889,1.202323609529759,-0.11827242278503895,0.3459784040561311,-0.34151131793657324,0.954123884167548,1.917270315417413,-0.7199196503135434,1.3343182502559603,0.9113436498871638,0.4267964258326052,1.4243805350193866,0.9824120538036047,-0.22847370331607397,0.7358896549563253,1.2423453819314823,-0.11827242278503895,-0.28462903979626186,0.4903913364797827,-0.1364482501831472,1.2688229452074793,-0.3224686466679636,2.530433704556057,0.1966311801772001,0.21347933237869962
2,948
Monooxygenase activity
6
9
2.519206
0.011762
P09601,P61457,Q14534,Q15800,Q16850,P30519
Functions
GO Molecular function
msigdb_gomf
101,138,272,246,52,28
2745,101,28,138,272,246,52,318,1218
-1.1567689963310013,2.1170726813344136,3.058164653086549,1.8715840661178529,1.2820013709130165,1.373145758933382,2.6852478237468818,1.1483806684923388,0.05945972020734923
2,948
Proteolysis
83
378
2.516865
0.01184
Q969V3,Q96PU5,P55786,P42785,Q9UIQ6,P42892,P46934,Q06787,P50579,P49069,Q96KC8,O75503,Q15392,Q92643,Q6ZXV5,Q9UHG3,P49755,O14737,Q96F07,P09960,Q96K76,Q9BUN8,O95831,Q15375,Q5JRX3,Q9Y4E8,P28072,Q4J6C6,P28070,Q9NR28,Q92896,P49721,P19474,Q9NZ08,Q8TAD4,O75976,O75844,Q99436,P38159,Q16740,Q9HB40,P23396,Q9BT78,Q9Y3B8,Q9P0J0,Q96T88,Q9BYT8,Q9H3G5,O43847,O95630,Q96A26,Q92783,Q96E52,P78318,O15372,Q9UKV5,O76024,P60900,Q9H300,Q9NQH7,Q16531,Q13547,Q9H1I8,P33908,Q9Y263,Q99797,Q8TCJ2,Q9BXK5,P20618,Q86TM6,O43464,O43242,Q13042,Q7Z2K6,Q9Y5A7,Q10713,P53634,P02786,P25787,P22695,P10619,Q8IYS1,Q9NZJ7
Processes and pathways
GO Biological process
msigdb_gobp
515,1,2,5,12,16,20,530,22,529,544,32,33,542,540,40,554,551,567,51,568,53,57,562,59,581,77,82,86,87,91,96,97,105,117,120,121,122,130,136,141,146,153,159,176,181,186,188,189,192,205,212,229,266,292,299,313,315,325,326,324,341,346,355,359,374,373,389,391,405,400,399,412,432,438,447,445,442,461,477,476,496,517
2317,2655,656,2172,1694,694,551,657,2446,2928,2778,1656,1440,292,2832,399,1722,400,953,1936,189,1021,1441,2895,997,1245,777,1442,1886,1860,32,2319,1335,121,641,120,313,1756,1136,1392,1969,938,673,192,1622,57,2049,2419,442,707,2821,2525,2376,779,2735,2479,1827,1916,1726,1394,854,2504,51,1444,476,2527,977,2716,1565,1829,1395,663,2810,2145,97,2506,391,2422,2737,2028,477,146,721,2215,461,1972,957,2280,1863,2216,86,77,737,2766,1501,2242,2533,1026,2053,1226,355,796,1759,2482,1280,2757,612,1256,130,1502,2327,5,16,2111,2283,871,2730,20,1700,1628,1539,751,529,1365,1797,1077,96,554,1669,1670,1730,22,1094,1732,1001,1095,1204,1542,1078,445,834,2151,1028,1765,1733,2,2537,2882,315,1055,2801,1341,1370,1506,614,2329,1342,2093,1056,1473,1895,1831,1832,1673,2879,784,1948,266,1870,2943,1507,2288,753,1545,530,1006,447,2825,724,412,1079,1057,1058,2250,1032,1771,1263,1509,2564,341,2461,1772,1511,2005,2184,2357,2381,1316,2889,839,2908,1283,1147,1709,1773,2650,1451,1950,2618,2796,562,1452,33,2513,1513,2540,2223,324,136,1574,82,1922,59,2409,2788,1407,1150,1840,2095,1422,540,787,432,2384,1901,2437,405,1842,1377,2310,635,802,496,1425,1741,2914,2068,1378,117,1981,2733,373,1808,878,1743,2585,1844,2411,681,542,1127,2228,212,1845,1983,91,880,2367,623,1481,1041,1101,515,205,756,2567,866,229,567,1043,2678,1155,692,826,568,1178,544,1984,1,1926,181,1044,122,2159,2865,1156,374,899,2548,1460,153,53,389,186,1181,1382,1879,2343,1293,346,639,325,188,1324,1047,2570,616,2632,141,2077,1219,949,326,1557,2761,87,2475,2263,806,2020,1583,1432,1558,1242,105,517,1612,1015,176,2444,706,40,905,12,716,1087,579,1790,734,670,299,1297,993,2023,2203,685,807,1751,2345,1274,2134,1462,745,1526,1018,359,159,1359,581,655,1360,1964,438,1754,1966,2135,828,976
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,0.31322807591179413,-0.26583072691689574,-0.8679522324143034,-0.3224686466679636,-0.7199196503135434,0.537486950272112,0.7209443730522314,0.11140380677844741,-0.576695277069889,1.5126086522989541,-0.3224686466679636,-0.41851760347793965,2.202984027932319,0.31322807591179413,-0.6785213070020842,0.5995008148293052,-0.11827242278503895,0.17971792076718154,0.12858251145984356,0.7656273000310847,1.537489972244893,0.4427821773887004,-0.8464982748968118,0.3296339066521189,1.4243805350193866,0.6908991641556643,0.17971792076718154,-1.0211206524758603,0.09415745775210213,0.5218448013237352,0.36226201680927644,0.6908991641556643,0.07684293929142288,0.7209443730522314,-0.41851760347793965,3.8435086970139305,-0.3798459053107705,1.6597947156561212,0.17971792076718154,1.9624778628651733,-0.5366148538627052,-1.5905769604580335,0.09415745775210213,0.9964874283803038,0.2967604582024043,-0.825148078218146,-0.1001715700836958,1.8021350389030668,2.6852478237468818,0.968290969875735,1.6356088521917012,0.07684293929142288,-0.046312846762206455,-0.34151131793657324,-0.6579670071768167,0.00689245382919885,1.0937591810735925,0.5840797855852801,1.1347895625307758,1.6234650069627081,-0.010771004982313778,0.17971792076718154,-0.8464982748968118,0.6148675201656797,-0.9548257864570027,1.8715840661178529,-0.4771701196736191,0.05945972020734923,0.24698227118508845,1.1347895625307758,-0.154699664595971,-1.1797869757098827,2.2453051777175066,-0.7617103122164987,-0.596873097659703,0.394648358795702,-0.43798169806465925,-0.17302728582659577,-0.08214508712671734,-0.154699664595971,0.04200726311648557,2.095324359314597,0.7656273000310847,-0.19143174128541807,0.1966311801772001,1.6718371053502799,-0.7407654856874151,0.5061463962970855,2.8893796757735113,0.2967604582024043,3.368863420764839,0.4903913364797827,0.1456940908786263,0.6757985361220961,-0.28462903979626186,0.4745792189320432,0.5530732376857973,1.188900583250081,0.00689245382919885,0.21347933237869962,-0.43798169806465925,-0.5566094692716574,0.537486950272112,0.394648358795702,-0.26583072691689574,-0.6579670071768167,0.024485024344763594,-0.5167106212981979,-0.1001715700836958,0.4587096364267473,-0.1364482501831472,0.1966311801772001,1.0384421790618117,1.7669871409132532,-0.028505915233174372,0.6757985361220961,0.5686040539973861,-0.028505915233174372,-0.3991392521076305,0.8969895762705655,-0.26583072691689574,-0.3991392521076305,-0.5167106212981979,0.36226201680927644,0.23026286775039087
2,948
serine protease
8
20
2.51423
0.011929
Q9H300,P42785,Q16740,Q9HB40,Q4J6C6,O95870,O43464,Q9H3G5
Functions
Panther Protein class
panther_protein_class
325,5,136,141,82,401,400,188
657,400,401,476,2323,1565,1501,1256,5,1700,784,136,82,2437,636,1809,325,188,141,1990
0.5530732376857973,0.9399105014520449,0.9399105014520449,0.8245003681365923,-0.6579670071768167,-0.17302728582659577,-0.1364482501831472,0.024485024344763594,3.574391697694004,-0.24711250387957184,0.4107519613001489,1.8830510514184668,2.2976278530369267,-0.7407654856874151,0.5840797855852801,-0.3035081182804855,1.1347895625307758,1.6234650069627081,1.8715840661178529,-0.41851760347793965
2,948
Carboxylic acid transport
7
32
2.508745
0.012116
Q9H2D1,P07602,Q9Y619,P53985,Q96QD8,Q9BQT8,P30825
Processes and pathways
GO Biological process
msigdb_gobp
4,110,81,50,118,23,221
2928,365,888,641,1223,1307,110,809,643,1396,1139,221,1629,50,2844,1171,2650,1122,1284,1923,624,916,118,23,4,917,1385,804,517,230,1328,81
-2.8388595641615995,1.0105173832723406,0.2967604582024043,0.5686040539973861,0.04200726311648557,-0.010771004982313778,2.06249462948218,0.37848518872114384,0.5686040539973861,-0.06419237620988717,0.09415745775210213,1.4624128836284802,-0.20991366611478418,2.7136633954590907,-1.4904417735103144,0.07684293929142288,-0.9768137628162359,0.11140380677844741,0.00689245382919885,-0.3798459053107705,0.5995008148293052,0.2802305948711232,1.9960752529228047,3.118706149066854,3.666003780285035,0.2802305948711232,-0.046312846762206455,0.394648358795702,0.7656273000310847,1.4243805350193866,-0.010771004982313778,2.3183799967279364
2,948
EF-hand domain pair [IPR011992]
20
50
2.502917
0.012317
P19174,Q96AY3,P14649,P80303,Q03001,P0DP25,Q14257,Q9NWM8,O95202,Q9UBV8,O43852,Q66K14,Q8NF37,Q9UM19,Q9Y680,Q9H8M7,Q15293,Q12841,Q02818,Q96D71
Sequence
InterPro Superfamily
interpro_homologous_superfamily
264,534,662,30,421,674,41,187,697,593,74,203,727,215,90,616,621,371,126,127
1304,74,1442,888,697,1467,1916,674,1277,2876,2175,662,2810,264,2028,1312,999,799,892,1630,1055,30,126,421,371,1034,41,2616,621,203,927,2696,1711,1424,1347,1425,727,534,127,742,2587,992,1325,616,187,593,1328,215,2266,90
-0.010771004982313778,2.3493216246615503,-0.1001715700836958,0.2967604582024043,0.5061463962970855,-0.11827242278503895,-0.3798459053107705,0.537486950272112,0.00689245382919885,-1.6671884467700155,-0.5566094692716574,0.5530732376857973,-1.3683690925791896,1.3082387048731943,-0.45753228412024466,-0.010771004982313778,0.1966311801772001,0.394648358795702,0.2967604582024043,-0.20991366611478418,0.16273905820118395,3.0494454126243524,1.9399333103611618,0.9113436498871638,0.9964874283803038,0.17971792076718154,2.8712191617408704,-0.9329466915129715,0.5995008148293052,1.549877201936574,0.2636380221709174,-1.0434417517569528,-0.24711250387957184,-0.08214508712671734,-0.028505915233174372,-0.08214508712671734,0.4745792189320432,0.7358896549563253,1.9399333103611618,0.4587096364267473,-0.8679522324143034,0.21347933237869962,-0.010771004982313778,0.6148675201656797,1.6356088521917012,0.660645419060983,-0.010771004982313778,1.5001141584399327,-0.596873097659703,2.2136033965250372
2,948
Positive regulation of immune response
20
68
2.499404
0.01244
Q9NUD5,P19174,P23396,Q9NUQ9,Q08722,Q07666,Q15233,Q96PK6,O14920,P23246,P02786,P43243,Q96IZ0,Q9NR50,O96028,P01889,P04439,Q07021,Q8WXF1,O15400
Processes and pathways
GO Biological process
msigdb_gobp
8,264,146,407,275,288,165,297,424,444,442,452,456,457,335,339,348,226,492,237
424,237,2139,1022,1443,2049,335,2448,339,442,1223,348,1416,2575,1394,2527,977,1276,891,1999,1566,264,444,146,1114,1534,1795,2378,1199,452,1200,2729,871,1366,2428,723,1341,1370,1976,753,226,288,1006,1598,275,2332,1546,1058,1405,2308,165,1264,2723,2874,2487,492,2678,456,297,2865,1216,506,457,8,407,1049,669,734
0.8969895762705655,1.3860113542851535,-0.5366148538627052,0.17971792076718154,-0.1001715700836958,-0.4771701196736191,1.1074790838974617,-0.7617103122164987,1.0937591810735925,0.8825879960378804,0.04200726311648557,1.06618870455087,-0.08214508712671734,-0.8679522324143034,-0.06419237620988717,-0.825148078218146,0.21347933237869962,0.00689245382919885,0.2967604582024043,-0.43798169806465925,-0.17302728582659577,1.3082387048731943,0.8825879960378804,1.825409057538314,0.11140380677844741,-0.154699664595971,-0.3035081182804855,-0.6991718914520957,0.05945972020734923,0.8681385994260129,0.05945972020734923,-1.1110891268052037,0.31322807591179413,-0.046312846762206455,-0.7407654856874151,0.4745792189320432,-0.028505915233174372,-0.046312846762206455,-0.41851760347793965,0.4427821773887004,1.4370951229364066,1.2423453819314823,0.1966311801772001,-0.19143174128541807,1.2688229452074793,-0.6579670071768167,-0.154699664595971,0.16273905820118395,-0.06419237620988717,-0.6375081142813843,1.7077643034433876,0.024485024344763594,-1.0884248463707054,-1.641504220074868,-0.7827550573182713,0.8098565473687283,-1.0211206524758603,0.8681385994260129,1.188900583250081,-1.5905769604580335,0.05945972020734923,0.7804203434389911,0.8681385994260129,3.4886450034761873,0.9399105014520449,0.17971792076718154,0.5530732376857973,0.4745792189320432
2,948
Alcohol binding
6
15
2.487669
0.012858
Q14108,O15118,P45880,P21796,P35610,P09455
Functions
GO Molecular function
msigdb_gomf
162,129,71,111,178,184
129,659,1969,1163,184,111,1664,2900,178,71,1768,162,308,991,1483
1.917270315417413,0.5530732376857973,-0.41851760347793965,0.07684293929142288,1.6356088521917012,2.0514955668887254,-0.22847370331607397,-1.8781849174669127,1.6597947156561212,2.369826344771198,-0.28462903979626186,1.7315509278111096,1.161929368281666,0.21347933237869962,-0.11827242278503895
2,948
Amide binding
18
103
2.482888
0.013032
Q15392,P55786,Q9Y584,Q8WTV0,P45880,Q9NZ08,P00374,Q9NQX7,Q9UIQ6,P07602,P24390,P42892,P21796,P35610,O43731,P55899,Q9Y680,O00264
Functions
GO Molecular function
msigdb_gomf
33,2,133,68,71,105,10,142,12,110,15,16,111,178,19,115,90,92
2710,774,92,789,1993,2936,657,1858,608,1619,2499,19,2638,2555,1443,10,339,348,1661,2941,110,1726,869,475,977,2939,1395,2881,111,1664,2822,15,1498,2280,2811,2578,1567,178,1228,2282,427,2425,16,2885,71,2056,1365,1762,2662,1367,1592,503,2429,1542,2,115,2302,923,1767,1206,1143,1207,2721,959,1314,676,2307,912,2564,1081,2463,1082,33,454,2095,637,68,2368,455,534,1682,1268,2942,989,1216,898,2441,186,1714,969,578,1411,142,1583,105,517,1788,437,12,1490,1131,133,90
-1.0884248463707054,0.4107519613001489,2.1816663680647275,0.394648358795702,-0.43798169806465925,-3.6836870365757868,0.5530732376857973,-0.34151131793657324,0.6148675201656797,-0.20991366611478418,-0.8039006614231072,3.1953050908815848,-0.9768137628162359,-0.8464982748968118,-0.1001715700836958,3.433165798062894,1.0937591810735925,1.06618870455087,-0.22847370331607397,-4.106887525702641,2.06249462948218,-0.26583072691689574,0.31322807591179413,0.8245003681365923,0.21347933237869962,-4.019022555973939,-0.06419237620988717,-1.7190065204560596,2.0514955668887254,-0.22847370331607397,-1.392516309666817,3.2622578968216644,-0.1364482501831472,-0.6171437624952562,-1.3683690925791896,-0.8679522324143034,-0.17302728582659577,1.6597947156561212,0.04200726311648557,-0.6171437624952562,0.8969895762705655,-0.7407654856874151,3.245617927748801,-1.77143566283669,2.369826344771198,-0.4771701196736191,-0.046312846762206455,-0.28462903979626186,-0.9989116898321668,-0.046312846762206455,-0.19143174128541807,0.7804203434389911,-0.7407654856874151,-0.154699664595971,3.711080088907221,2.007216460441714,-0.6375081142813843,0.2636380221709174,-0.28462903979626186,0.05945972020734923,0.09415745775210213,0.05945972020734923,-1.0884248463707054,0.23026286775039087,-0.010771004982313778,0.537486950272112,-0.6375081142813843,0.2802305948711232,-0.8464982748968118,0.1456940908786263,-0.7617103122164987,0.1456940908786263,2.9967531033007075,0.8681385994260129,-0.4968959727005952,0.5840797855852801,2.4206641920055536,-0.6785213070020842,0.8681385994260129,0.7358896549563253,-0.22847370331607397,0.024485024344763594,-4.573600601391692,0.21347933237869962,0.05945972020734923,0.2967604582024043,-0.7407654856874151,1.6356088521917012,-0.24711250387957184,0.23026286775039087,0.6757985361220961,-0.06419237620988717,1.8715840661178529,-0.17302728582659577,2.095324359314597,0.7656273000310847,-0.28462903979626186,0.8969895762705655,3.368863420764839,-0.11827242278503895,0.11140380677844741,1.917270315417413,2.2136033965250372
2,948
Respiratory chain
10
30
2.479913
0.013141
O96000,Q9P0J0,P00403,P03886,Q9UDW1,Q96CU9,O14949,Q6DKK2,Q9Y6M9,O43676
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
36,176,174,145,274,210,151,152,220,24
2024,151,24,2047,1968,1247,1659,2627,2602,36,174,145,2107,1363,2395,477,2823,1338,2793,2748,2178,1345,2289,152,309,210,1068,176,274,220
-0.45753228412024466,1.8021350389030668,3.1101097166990783,-0.4771701196736191,-0.41851760347793965,0.024485024344763594,-0.22847370331607397,-0.9548257864570027,-0.9111754241704362,2.943403293840926,1.6718371053502799,1.8369991927238165,-0.5167106212981979,-0.046312846762206455,-0.7199196503135434,0.8245003681365923,-1.392516309666817,-0.028505915233174372,-1.2967067971056643,-1.1567689963310013,-0.5566094692716574,-0.028505915233174372,-0.6171437624952562,1.8021350389030668,1.161929368281666,1.5250671893501497,0.16273905820118395,1.6718371053502799,1.2820013709130165,1.4750164810877993
2,948
Protein polyubiquitination
8
50
2.469774
0.01352
Q96PU5,P55786,P19474,Q9Y263,Q9UKV5,Q9UIQ6,Q86TM6,P46934
Processes and pathways
GO Biological process
msigdb_gobp
1,2,97,359,299,12,405,20
694,777,1939,673,97,2028,1501,1226,1759,20,1204,2,1341,1370,1673,1948,2288,412,1771,2461,1511,2357,725,1316,1452,1574,1150,1901,1010,405,2741,1378,878,1043,1,1181,1293,12,716,1087,579,1790,1962,299,2023,2203,2345,359,1360,1964
0.5061463962970855,0.4107519613001489,-0.3991392521076305,0.537486950272112,2.1279058027565836,-0.45753228412024466,-0.1364482501831472,0.04200726311648557,-0.28462903979626186,3.178401473028381,0.05945972020734923,3.711080088907221,-0.028505915233174372,-0.046312846762206455,-0.22847370331607397,-0.3991392521076305,-0.6171437624952562,0.925650523668678,-0.28462903979626186,-0.7617103122164987,-0.1364482501831472,-0.6785213070020842,0.4745792189320432,-0.010771004982313778,-0.1001715700836958,-0.17302728582659577,0.09415745775210213,-0.36063683389058815,0.1966311801772001,0.9399105014520449,-1.133870114754212,-0.046312846762206455,0.31322807591179413,0.17971792076718154,3.8435086970139305,0.07684293929142288,0.00689245382919885,3.368863420764839,0.4903913364797827,0.1456940908786263,0.6757985361220961,-0.28462903979626186,-0.3991392521076305,1.188900583250081,-0.43798169806465925,-0.5566094692716574,-0.6579670071768167,1.0384421790618117,-0.028505915233174372,-0.3991392521076305
2,948
Negative regulation of mrna splicing via spliceosome
9
14
2.467905
0.013591
Q07021,P22626,P38159,Q13242,Q08170,O75494,P61978,P26368,P98175
Processes and pathways
GO Biological process
msigdb_gobp
226,227,130,329,556,390,139,239,382
2206,390,227,239,1862,130,139,382,226,556,2220,329,1478,597
-0.576695277069889,0.954123884167548,1.4243805350193866,1.3860113542851535,-0.34151131793657324,1.917270315417413,1.8715840661178529,0.9824120538036047,1.4370951229364066,0.7059476590359905,-0.576695277069889,1.121155788951183,-0.11827242278503895,0.6454394534643092
2,948
Submucous cleft of soft and hard palate
6
24
2.457162
0.014004
O43505,Q15392,Q9Y619,Q96DF8,O75844,Q08J23
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
65,33,81,310,121,222
1109,1332,65,1162,121,1249,2212,1092,1796,1262,1735,222,1511,1061,33,342,1288,1779,310,2632,1069,2680,2871,81
0.11140380677844741,-0.028505915233174372,2.4408320972461683,0.07684293929142288,1.9624778628651733,0.024485024344763594,-0.576695277069889,0.12858251145984356,-0.3035081182804855,0.024485024344763594,-0.26583072691689574,1.4624128836284802,-0.1364482501831472,0.16273905820118395,2.9967531033007075,1.0937591810735925,0.00689245382919885,-0.28462903979626186,1.161929368281666,-0.9548257864570027,0.16273905820118395,-1.0211206524758603,-1.6159676102963427,2.3183799967279364
2,948
Phenotypic variability
34
96
2.456164
0.014043
Q9Y4W6,Q9H061,P50995,P00374,P03886,Q70HW3,Q06787,O60762,Q6PI48,P04350,Q6P4A7,Q92733,O00330,P00403,Q9NWS8,O95140,Q969G3,P00846,P43243,O14979,Q8TD16,Q14697,O95470,O60313,P36551,Q9Y263,P07602,Q8NI60,P06753,Q9NQT5,Q9Y276,Q5THJ4,O00429,Q9NZJ7
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
655,132,512,10,145,18,530,659,164,537,680,167,550,174,570,426,704,60,452,70,209,595,214,460,612,359,110,497,618,506,508,254,628,517
550,628,70,1304,460,659,1756,426,1724,214,10,174,60,1249,145,537,618,110,2421,2714,1625,854,979,870,1917,1891,1759,1590,612,2535,2217,2301,1399,709,452,1666,1203,1668,1367,1281,512,1570,2595,1799,1733,2284,1141,2750,837,2058,2405,530,1978,1402,1033,1034,2334,1080,595,1451,1839,2904,254,1422,680,164,18,497,209,741,167,704,1102,1129,1239,132,2570,1986,2632,506,1784,2919,1386,570,517,1185,2572,1130,1086,807,359,508,1435,1220,655,1819
0.7059476590359905,0.5840797855852801,2.3800421400870855,-0.010771004982313778,0.8390951028692502,0.5530732376857973,-0.28462903979626186,0.8969895762705655,-0.26583072691689574,1.5001141584399327,3.433165798062894,1.6718371053502799,2.530433704556057,0.024485024344763594,1.8369991927238165,0.7209443730522314,0.5995008148293052,2.06249462948218,-0.7407654856874151,-1.0884248463707054,-0.20991366611478418,0.3296339066521189,0.21347933237869962,0.31322807591179413,-0.3798459053107705,-0.36063683389058815,-0.28462903979626186,-0.19143174128541807,0.6148675201656797,-0.825148078218146,-0.576695277069889,-0.6375081142813843,-0.06419237620988717,0.4903913364797827,0.8681385994260129,-0.22847370331607397,0.05945972020734923,-0.22847370331607397,-0.046312846762206455,0.00689245382919885,0.7656273000310847,-0.17302728582659577,-0.8895109457490417,-0.3035081182804855,-0.26583072691689574,-0.6171437624952562,0.09415745775210213,-1.1567689963310013,0.3459784040561311,-0.4771701196736191,-0.7199196503135434,0.7358896549563253,-0.41851760347793965,-0.06419237620988717,0.17971792076718154,0.17971792076718154,-0.6579670071768167,0.1456940908786263,0.6454394534643092,-0.1001715700836958,-0.3224686466679636,-1.9325351999326172,1.3472994325027918,-0.08214508712671734,0.537486950272112,1.7196739808433925,3.2289128066153725,0.7951633152994793,1.5250671893501497,0.4587096364267473,1.7077643034433876,0.5061463962970855,0.12858251145984356,0.11140380677844741,0.04200726311648557,1.917270315417413,-0.8464982748968118,-0.41851760347793965,-0.9548257864570027,0.7804203434389911,-0.28462903979626186,-2.332755838948225,-0.046312846762206455,0.6908991641556643,0.7656273000310847,0.07684293929142288,-0.8464982748968118,0.11140380677844741,0.1456940908786263,0.394648358795702,1.0384421790618117,0.7804203434389911,-0.08214508712671734,0.05945972020734923,0.5686040539973861,-0.3035081182804855
2,948
Abnormal brainstem mri signal intensity
7
21
2.455638
0.014063
O96000,Q8IUX1,P03886,Q96CU9,O43676,O95831,Q9Y6M9
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
36,273,145,210,24,57,220
24,2047,1968,1247,57,36,145,2395,2823,1367,2748,309,273,2622,1102,210,505,1068,1854,1220,220
3.1101097166990783,-0.4771701196736191,-0.41851760347793965,0.024485024344763594,2.6085391476555078,2.943403293840926,1.8369991927238165,-0.7199196503135434,-1.392516309666817,-0.046312846762206455,-1.1567689963310013,1.161929368281666,1.2820013709130165,-0.9329466915129715,0.12858251145984356,1.5250671893501497,0.7804203434389911,0.16273905820118395,-0.3224686466679636,0.05945972020734923,1.4750164810877993
2,948
Retrograde vesicle mediated transport golgi to endoplasmic reticulum
9
29
2.451971
0.014208
Q92538,Q9P2W9,P49755,P24390,P61923,Q8TD16,O43731,Q96RQ1,Q9Y282
Processes and pathways
GO Biological process
msigdb_gobp
541,358,554,15,367,209,19,180,62
1133,1189,1052,1619,19,1755,1531,15,1339,1258,1503,554,2645,367,620,1770,786,209,2158,541,1290,180,1957,933,731,1271,358,2100,62
0.09415745775210213,0.05945972020734923,0.16273905820118395,-0.20991366611478418,3.1953050908815848,-0.28462903979626186,-0.154699664595971,3.2622578968216644,-0.028505915233174372,0.024485024344763594,-0.1364482501831472,0.7059476590359905,-0.9768137628162359,1.0105173832723406,0.5995008148293052,-0.28462903979626186,0.4107519613001489,1.5250671893501497,-0.5366148538627052,0.7209443730522314,0.00689245382919885,1.6597947156561212,-0.3991392521076305,0.2636380221709174,0.4745792189320432,0.024485024344763594,1.0384421790618117,-0.4968959727005952,2.5106832011938405
2,948
Phospholipid binding
30
85
2.451454
0.014228
Q8NCC3,P50995,Q9NS86,P50897,Q9UKS6,O14773,Q92643,Q92538,Q14108,Q96L92,O60749,Q9Y5X3,O15020,Q8WTV0,Q9Y2I1,Q9NV70,P45880,Q9UNF0,Q9UJZ1,Q9H4A6,Q92783,Q9H6U6,O60313,P09525,P07602,P21796,Q12965,Q9Y4G8,O14964,Q9NZJ7
Functions
GO Molecular function
msigdb_gomf
3,512,525,144,670,657,542,541,162,306,48,582,696,68,717,715,71,735,734,731,212,606,460,718,110,111,754,248,501,517
1071,657,501,696,1440,1722,953,1937,460,1074,1305,48,2275,1245,1223,1827,110,1275,1163,1394,718,1251,2528,764,1396,111,1470,1026,1195,1760,71,2001,1076,1503,144,512,2536,2749,1207,924,1921,754,1008,2564,1510,2004,162,1512,2407,2617,1148,2255,863,3,815,68,541,542,212,1878,306,2548,2624,2160,991,1608,933,731,606,525,715,517,1856,1933,734,670,735,1298,717,1359,2416,248,2373,2135,582
0.1456940908786263,0.5530732376857973,0.7804203434389911,0.5061463962970855,-0.1001715700836958,-0.26583072691689574,0.23026286775039087,-0.3991392521076305,0.8390951028692502,0.1456940908786263,-0.010771004982313778,2.741891805558301,-0.6171437624952562,0.024485024344763594,0.04200726311648557,-0.3224686466679636,2.06249462948218,0.00689245382919885,0.07684293929142288,-0.06419237620988717,0.4745792189320432,0.024485024344763594,-0.825148078218146,0.4267964258326052,-0.06419237620988717,2.0514955668887254,-0.11827242278503895,0.17971792076718154,0.05945972020734923,-0.28462903979626186,2.369826344771198,-0.43798169806465925,0.1456940908786263,-0.1364482501831472,1.8485582976056778,0.7656273000310847,-0.825148078218146,-1.1567689963310013,0.05945972020734923,0.2636380221709174,-0.3798459053107705,0.4427821773887004,0.1966311801772001,-0.8464982748968118,-0.1364482501831472,-0.43798169806465925,1.7315509278111096,-0.1364482501831472,-0.7199196503135434,-0.9329466915129715,0.09415745775210213,-0.596873097659703,0.3296339066521189,3.711080088907221,0.37848518872114384,2.4206641920055536,0.7209443730522314,0.7209443730522314,1.5126086522989541,-0.34151131793657324,1.1754359209634744,-0.825148078218146,-0.9329466915129715,-0.5366148538627052,0.21347933237869962,-0.19143174128541807,0.2636380221709174,0.4745792189320432,0.6301802761408241,0.7507838500099976,0.4903913364797827,0.7656273000310847,-0.3224686466679636,-0.3798459053107705,0.4745792189320432,0.5530732376857973,0.4745792189320432,0.00689245382919885,0.4903913364797827,-0.028505915233174372,-0.7199196503135434,1.373145758933382,-0.6785213070020842,-0.5167106212981979,0.6757985361220961
2,948
Iron ion binding
10
20
2.449729
0.014296
Q32P28,P31350,O75845,Q15800,Q16850,Q9NWT6,P13674,P22830,O15460,Q6UW02
Functions
GO Molecular function
msigdb_gomf
198,419,201,246,52,376,55,443,398,318
607,398,201,55,443,2280,419,1766,1372,246,52,198,318,2890,1218,468,2493,1522,376,760
0.6148675201656797,0.9399105014520449,1.549877201936574,2.627845336521186,0.8825879960378804,-0.6171437624952562,0.9113436498871638,-0.28462903979626186,-0.046312846762206455,1.373145758933382,2.6852478237468818,1.574545797147203,1.1483806684923388,-1.7978838385941391,0.05945972020734923,0.8390951028692502,-0.7827550573182713,-0.1364482501831472,0.9964874283803038,0.4427821773887004
2,948
Oxidoreductase
25
109
2.449372
0.014311
Q16134,P00374,O43169,Q14534,P03886,Q9BY49,Q15392,P14406,O94788,Q9H9P8,P30837,Q9P0J0,P00403,Q8N4Q0,Q16850,O95831,Q8N0U8,Q15067,O75845,Q96CU9,Q13423,Q9Y6M9,Q15800,Q14739,P00367
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
262,10,14,272,145,155,33,34,37,169,45,176,174,49,52,57,191,193,201,210,216,220,246,116,252
2024,1439,868,14,1332,2668,792,1561,2047,1968,201,640,2872,37,1659,57,853,2593,252,10,1660,174,145,2420,2525,486,2671,1625,854,1362,2940,1627,2863,2717,955,34,2629,1363,2786,1364,610,870,2279,2351,2823,2719,2577,418,2533,45,1889,419,2534,1472,612,2507,2453,2829,799,2812,2873,1762,2594,2400,2178,1865,1764,1894,1476,959,1372,1172,216,272,116,2382,193,33,246,262,1345,2289,52,2383,2807,576,2598,2621,191,49,2938,566,2584,1427,210,1155,2789,468,155,578,1411,169,1068,653,176,1787,2572,274,220
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2,948
Sensorimotor neuropathy
13
27
2.443991
0.014526
Q8N2K0,Q15120,Q9Y2R0,P07602,P00403,P03886,Q5THJ4,Q5KU26,O60313,O95831,P00846,O00429,Q9NZJ7
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
636,231,300,110,174,145,254,349,460,57,60,628,517
628,1072,460,57,174,60,145,794,110,2718,2452,2425,1281,1260,1733,2456,1978,1032,231,349,254,636,1013,733,517,300,655
0.5840797855852801,0.1456940908786263,0.8390951028692502,2.6085391476555078,1.6718371053502799,2.530433704556057,1.8369991927238165,0.394648358795702,2.06249462948218,-1.0884248463707054,-0.7617103122164987,-0.7407654856874151,0.00689245382919885,0.024485024344763594,-0.26583072691689574,-0.7617103122164987,-0.41851760347793965,0.17971792076718154,1.4116285225499112,1.06618870455087,1.3472994325027918,0.5840797855852801,0.1966311801772001,0.4745792189320432,0.7656273000310847,1.188900583250081,0.5686040539973861
2,948
Response to oxygen levels
14
61
2.436733
0.014821
P02786,Q9Y487,P55786,P09601,Q04656,Q15120,Q96A26,P00846,Q06330,Q9NY64,Q9NWT6,Q8N511,O95831,P30519
Processes and pathways
GO Biological process
msigdb_gobp
442,89,2,101,322,231,205,60,47,408,376,149,57,28
1692,1304,997,1968,2745,938,57,2419,2448,60,1249,442,2420,2376,660,2735,526,101,1829,2810,1396,2028,28,2281,1256,2217,1027,2327,2746,1365,1920,811,2,1029,2329,1372,322,47,1600,2184,231,463,2514,1515,802,149,2158,2012,1809,2228,205,1155,1216,1905,376,408,685,2345,89,1691,2270
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2,948