term stringlengths 2 121 | overlap int64 6 281 | setsize int64 7 499 | score float64 1.96 10.6 | pval float64 0 0.05 | edge stringlengths 41 1.97k | type stringclasses 5 values | subtype stringclasses 24 values | subtype_key stringclasses 24 values | edge_idxs stringlengths 11 1.17k | ann_idxs stringlengths 19 2.31k | ann_vals stringlengths 124 9.94k | sig_size int64 2.2k 3.73k |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Action tremor | 16 | 61 | 2.873155 | 0.004064 | P41440,Q9NZJ7,O75787,Q96RL7,Q9NR77,O14773,P00846,Q14108,O75027,O75306,Q99720,P35637,Q9H6K4,P07602,Q9Y5Y0,P03886 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 224,359,434,408,265,291,8,71,364,238,16,311,152,25,220,218 | 2933,291,2231,926,364,238,1523,434,1250,1328,8,218,2442,3157,25,2645,2491,1217,2587,1974,847,1258,3011,1528,2864,311,224,2138,2452,2828,1478,1011,1308,71,1036,3045,638,1195,2879,1793,1645,531,459,2055,3192,408,3340,2167,16,784,1456,152,1056,265,3090,2271,359,653,1287,809,220 | -0.7611361133509404,1.2950952054305622,-0.35608198164205196,0.34547107923826165,1.1110006232313312,1.454160780076086,-0.01249402587824863,0.9706140497703232,0.12578776192278873,0.0802551137654914,3.8776383909815935,1.5460733812057033,-0.46011072625306215,-0.9951140817015471,3.363757087870197,-0.5669609774156144,-0.48655380913412877,0.1483485632559681,-0.5399768938790059,-0.2298275615859757,0.4089078305742396,0.12578776192278873,-0.8183811716642784,-0.01249402587824863,-0.7046914435829653,1.2458689372071072,1.5157190967783831,-0.3050870328676839,-0.46011072625306215,-0.67676342294761,0.010907357520276812,0.28092127296462205,0.10309040916855126,2.6134173692391474,0.25915163831136523,-0.8473098246926763,0.6521418328596066,0.17077418478294684,-0.7046914435829653,-0.13170970617137487,-0.059733927382445505,0.8055968854608062,0.9526587487920226,-0.2547520329568809,-1.0253252659977525,1.0415205771938503,-1.3401781938177342,-0.3050870328676839,3.6370039877820517,0.4712633310682175,0.034165029853640824,1.916883074110937,0.25915163831136523,1.391439557045039,-0.8764458292816217,-0.35608198164205196,1.145220634988901,0.6324870611210252,0.12578776192278873,0.45059639260802203,1.5460733812057033 | 3,477 |
Mib complex | 6 | 10 | 2.86938 | 0.004113 | Q9NX63,Q9BUR5,Q5XKP0,Q6UXV4,Q13505,Q9Y512 | Localization | GO Cellular component | msigdb_gocc | 294,264,230,268,337,223 | 1088,1475,337,368,230,268,264,1117,294,223 | 0.2152252789325902,0.010907357520276812,1.1791016511727834,1.1110006232313312,1.5004365612200485,1.3755732121053947,1.391439557045039,0.2152252789325902,1.2950952054305622,1.5309311892284372 | 3,477 |
Reduced visual acuity | 37 | 130 | 2.86727 | 0.00414 | P00846,P53701,P50897,Q9H9S5,O00429,Q15051,Q9H6K4,P07602,O43676,P31939,P06865,Q9UHX1,Q9H270,Q9Y375,P09622,P16278,P17900,Q9H061,Q96AA3,Q15043,Q96S66,Q86Y39,Q96CU9,P21912,Q9Y6M9,Q9Y5Y0,P03886,Q07021,P51798,Q9NZJ7,Q10713,O60313,O75306,Q9NPL8,P01889,P25054,Q9NZ08 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 8,266,20,283,528,405,152,25,27,541,292,36,424,426,428,50,310,56,444,198,589,331,78,202,613,220,218,599,343,359,600,234,238,495,620,373,128 | 655,2438,2534,1427,2180,2122,528,2183,2774,1293,1430,27,926,2024,234,1518,1124,238,1970,1572,2127,1771,2441,2643,618,3310,8,620,218,1973,3253,292,25,1873,2645,2282,428,2819,2491,50,310,2333,2191,3300,2650,202,2978,373,1725,3346,1780,2901,1528,541,2030,2134,2699,1823,1681,1182,1334,2984,2867,20,343,1131,266,3393,2243,3467,2246,1886,2408,1305,599,600,2148,3147,2557,2412,198,405,722,961,1344,2610,3461,1145,876,331,1744,738,971,1801,1450,2571,2213,1498,444,78,589,943,1413,2107,2573,3108,2524,56,424,1283,152,3295,283,495,1911,767,128,359,947,977,2677,36,2069,2725,426,1566,809,810,220,613 | 0.6127239700105706,-0.46011072625306215,-0.5131751901331499,0.034165029853640824,-0.33050110950497374,-0.3050870328676839,0.8055968854608062,-0.33050110950497374,-0.6490285776513719,0.10309040916855126,0.034165029853640824,3.330675073412696,0.34547107923826165,-0.2547520329568809,1.4850830339872365,-0.01249402587824863,0.1930659788602032,1.454160780076086,-0.2298275615859757,-0.036040615240763116,-0.3050870328676839,-0.13170970617137487,-0.46011072625306215,-0.5669609774156144,0.6716892768089571,-1.2752831992039835,3.8776383909815935,0.6716892768089571,1.5460733812057033,-0.2298275615859757,-1.1484283110266162,1.2950952054305622,3.363757087870197,-0.18045600562004682,-0.5669609774156144,-0.38183149261829497,0.9884770959627627,-0.67676342294761,-0.48655380913412877,2.8600703081678036,1.2458689372071072,-0.4077515144924765,-0.33050110950497374,-1.2432072777509597,-0.5669609774156144,1.591085893413555,-0.7896574082543483,1.093761710301451,-0.10756689934795993,-1.3730037178018255,-0.13170970617137487,-0.7328149058045688,-0.01249402587824863,0.7867740121764749,-0.2547520329568809,-0.3050870328676839,-0.594129530873194,-0.156005530653432,-0.08357550145023511,0.17077418478294684,0.0802551137654914,-0.7896574082543483,-0.7046914435829653,3.4447291832381413,1.1622031649520077,0.1930659788602032,1.3755732121053947,-1.5754619965695265,-0.35608198164205196,-3.920955863097363,-0.35608198164205196,-0.18045600562004682,-0.4338439486214293,0.10309040916855126,0.6911303718588904,0.6911303718588904,-0.3050870328676839,-0.9651232031602808,-0.5131751901331499,-0.4338439486214293,1.6207544213461318,1.0415205771938503,0.5325681239141068,0.32407975809190903,0.0802551137654914,-0.5399768938790059,-2.6675908680237392,0.1930659788602032,0.3878839297734311,1.1959167885724808,-0.10756689934795993,0.5122481028192044,0.32407975809190903,-0.13170970617137487,0.034165029853640824,-0.5131751901331499,-0.33050110950497374,0.010907357520276812,0.9706140497703232,2.55930399160172,0.7104660844148053,0.34547107923826165,0.057280464510361444,-0.2798379365454374,-0.5131751901331499,-0.9057916890941692,-0.48655380913412877,2.7801609678496,1.0062486792449554,0.12578776192278873,1.916883074110937,-1.2113748690313957,1.34361310413227,0.8614700219449289,-0.18045600562004682,0.49181353408407796,2.112700849689168,1.145220634988901,0.34547107923826165,0.32407975809190903,-0.5669609774156144,3.1678099470628176,-0.2547520329568809,-0.594129530873194,1.0062486792449554,-0.01249402587824863,0.45059639260802203,0.45059639260802203,1.5460733812057033,0.6911303718588904 | 3,477 |
Abnormality of corneal stroma | 6 | 15 | 2.853041 | 0.00433 | P10619,P04062,Q16625,Q13510,P16278,Q9Y5Z9 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 192,70,260,75,50,59 | 1430,286,70,192,50,1217,2587,2398,1478,75,260,3337,2421,1425,59 | 0.034165029853640824,1.3113456984812744,2.6134173692391474,1.650155885127456,2.8600703081678036,0.1483485632559681,-0.5399768938790059,-0.4338439486214293,0.010907357520276812,2.5702062195920785,1.391439557045039,-1.3401781938177342,-0.4338439486214293,0.057280464510361444,2.7598328946941053 | 3,477 |
Oxidative phosphorylation | 34 | 64 | 2.851873 | 0.004346 | O43920,P14406,P00846,P20674,Q96QE5,O75964,P24539,P56385,O43676,P14927,O95168,O00483,Q9Y375,P09622,Q9UJZ1,P36542,Q9UDW1,Q9BSK2,P27144,O95169,Q9Y6M9,P03886,P56134,P13073,P06576,P22695,O75306,Q9H3K2,P00403,O96000,Q16795,O14949,O14548,P51970 | Processes and pathways | GO Biological process | msigdb_gobp | 634,2,8,774,533,19,277,279,27,287,411,791,426,428,576,817,66,327,707,89,613,218,734,228,731,481,238,243,619,618,502,120,248,750 | 791,248,120,844,27,3236,634,1124,238,1970,1572,814,19,411,89,3352,1329,618,619,8,218,2442,2129,731,1173,428,1298,228,2,1674,287,1128,2191,774,481,277,1434,707,3346,3271,2901,1580,1581,817,1333,1302,2984,750,3100,734,279,3467,3129,502,3325,533,3340,2005,327,243,66,576,426,613 | 0.45059639260802203,1.4229478246834266,2.1629094522490995,0.4089078305742396,3.330675073412696,-1.1173081574095296,0.6521418328596066,0.1930659788602032,1.454160780076086,-0.2298275615859757,-0.036040615240763116,0.42981160276593183,3.468551690459964,1.0239295819857912,2.4593413890789497,-1.4060856588926407,0.0802551137654914,0.6716892768089571,0.6716892768089571,3.8776383909815935,1.5460733812057033,-0.46011072625306215,-0.3050870328676839,0.5122481028192044,0.17077418478294684,0.9884770959627627,0.10309040916855126,1.5004365612200485,4.053723242400452,-0.08357550145023511,1.3113456984812744,0.1930659788602032,-0.33050110950497374,0.4712633310682175,0.8798988183330019,1.34361310413227,0.034165029853640824,0.5527746697318787,-1.3730037178018255,-1.179782889725206,-0.7328149058045688,-0.036040615240763116,-0.036040615240763116,0.42981160276593183,0.0802551137654914,0.10309040916855126,-0.7896574082543483,0.49181353408407796,-0.9057916890941692,0.5122481028192044,1.34361310413227,-3.920955863097363,-0.9353499504290953,0.8429440113127525,-1.307605772494711,0.8055968854608062,-1.3401781938177342,-0.2298275615859757,1.2126492640347504,1.454160780076086,2.677067202689612,0.7296973686019401,1.0062486792449554,0.6911303718588904 | 3,477 |
Proton transporting two sector atpase complex | 15 | 24 | 2.848346 | 0.004395 | P56134,P21281,O75787,Q9Y487,P06576,Q15904,P00846,Q96IX5,O75964,Q8N511,P36543,Q93050,P24539,P56385,P36542 | Localization | GO Cellular component | msigdb_gocc | 734,662,434,594,731,229,8,460,19,51,748,153,277,279,817 | 3269,434,814,19,8,731,662,2589,277,1434,817,748,1782,1302,734,279,957,229,51,153,460,1562,594,924 | -1.179782889725206,0.9706140497703232,0.42981160276593183,3.468551690459964,3.8776383909815935,0.5122481028192044,0.6127239700105706,-0.5399768938790059,1.34361310413227,0.034165029853640824,0.42981160276593183,0.49181353408407796,-0.13170970617137487,0.10309040916855126,0.5122481028192044,1.34361310413227,0.32407975809190903,1.5004365612200485,2.8600703081678036,1.9033854568681277,0.9526587487920226,-0.01249402587824863,0.7104660844148053,0.3667387385449585 | 3,477 |
Antiporter activity | 8 | 11 | 2.839881 | 0.004513 | P41440,P08195,P51790,P12235,O95202,Q9UBX3,P12236,P51798 | Functions | GO Molecular function | msigdb_gomf | 224,412,166,295,177,55,276,343 | 177,1252,511,412,295,276,224,166,343,934,55 | 1.7510149601511857,0.12578776192278873,0.8243199236689244,1.0239295819857912,1.278766009486297,1.34361310413227,1.5157190967783831,1.8072650329398752,1.1622031649520077,0.34547107923826165,2.800347105622523 | 3,477 |
Sterol metabolism | 11 | 27 | 2.837707 | 0.004544 | Q9UBM7,P04062,P37268,Q14739,Q15800,O76062,O15118,Q15392,Q15125,P04035,O75845 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 227,70,39,107,76,77,113,114,406,185,286 | 113,730,286,77,815,1331,185,70,747,2978,2449,39,2903,583,3078,2987,3357,107,406,3042,114,962,76,415,227,1461,1422 | 2.2000380350552113,0.5122481028192044,1.3113456984812744,2.55930399160172,0.42981160276593183,0.0802551137654914,1.708173559202872,2.6134173692391474,0.49181353408407796,-0.7896574082543483,-0.46011072625306215,3.114311106742357,-0.7328149058045688,0.7104660844148053,-0.8764458292816217,-0.7896574082543483,-1.4060856588926407,2.284966007398189,1.0415205771938503,-0.8473098246926763,2.1877114381475624,0.32407975809190903,2.5702062195920785,1.0239295819857912,1.5157190967783831,0.034165029853640824,0.057280464510361444 | 3,477 |
Metabolism of lipids | 56 | 202 | 2.827411 | 0.004693 | Q9NTJ5,Q9BZF3,Q53GQ0,O15254,Q8NAN2,P38435,Q8NF37,P50897,Q9HBU6,Q14534,Q15125,P07602,Q9NZC3,Q8IV08,O75845,Q16850,Q96G23,P06865,P37268,Q96N66,P23786,P16278,P17900,P04035,Q8NCC3,P27544,Q9UMR5,P10619,O15121,P04062,Q16739,Q15067,Q13510,Q15800,O76062,P30536,Q06136,O00116,O95470,Q9NQZ5,Q9UG56,Q9NZJ7,Q9UBM7,Q15165,Q9NPH0,Q9P035,Q14739,P51648,P06280,Q6UWP7,P35790,Q9NPJ6,Q15392,Q9BY49,O43772,Q9H7Z7 | Processes and pathways | Reactome Pathways | msigdb_reactome | 394,133,261,385,402,143,403,20,284,151,406,25,156,157,286,415,289,292,39,174,49,50,310,185,58,60,65,192,321,70,72,200,75,76,77,210,83,340,94,222,361,359,227,102,105,360,107,109,239,369,241,384,114,250,124,256 | 811,340,2932,1769,3475,1966,770,2181,321,615,385,410,1003,926,124,1123,2536,1325,2126,2891,1374,617,1716,286,77,1328,94,1772,2644,1064,1717,1004,658,185,70,3471,1215,239,292,25,1873,2081,1673,192,2735,747,3392,2491,3344,1257,50,3119,310,3069,1723,2821,2492,1258,2978,49,2541,60,2696,210,1435,866,2398,2449,241,2497,39,143,2195,2032,2451,2825,1181,1727,904,2343,3408,1182,3456,483,20,109,1183,1533,2705,2903,2659,2500,3237,1184,3076,3402,3208,2553,1731,2554,3448,2987,2408,83,1942,1189,600,3474,75,1684,3357,151,107,3213,3460,2414,200,406,3042,102,2989,114,1488,3043,962,76,72,518,415,2799,261,1102,1195,825,369,1196,1444,1840,2568,157,989,531,2761,3278,545,402,586,58,3149,403,1997,1999,760,670,2571,1207,3245,289,174,2063,2423,2004,1048,1501,1755,2369,856,2472,672,3413,250,571,133,805,256,284,572,105,2312,384,222,394,3057,741,1509,1808,555,156,359,360,1664,654,227,361,2117,65,1706,1370,978,1121,892,1567 | 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| 3,477 |
Primary mitochondrial disease | 38 | 98 | 2.820939 | 0.004788 | Q6P4A7,Q9BUB7,Q8NI60,P00846,P20674,Q9NWS8,Q9Y2R0,Q6DKK2,O43676,P14927,Q9Y375,P12235,Q9UBX3,O43819,O75880,Q9NYY8,Q96IX5,Q86Y39,O95831,Q96CU9,O95169,Q9Y6M9,P03886,Q8N183,Q07021,P13073,Q5XKP0,Q99797,O60313,P22695,O75306,Q9NPL8,Q9NX14,P00403,Q16795,Q70HW3,O14949,P52815 | Drugs and Diseases | Protein Atlas Disease involvement | protein_atlas_disease_involvement | 262,784,781,8,774,270,17,155,27,287,426,295,55,694,323,462,460,331,454,78,89,613,218,738,599,228,230,630,234,481,238,495,767,619,502,115,120,752 | 791,120,27,3236,694,234,1124,238,1970,1572,928,323,89,1329,454,619,8,218,2442,2282,1173,1091,295,228,1817,287,2191,774,481,1434,3346,2901,3422,1094,2342,1978,2984,2596,752,2869,1337,2094,958,599,502,1102,1640,1739,875,2301,230,155,262,115,1443,331,1017,738,1996,781,971,2420,78,1846,460,1754,3410,630,2922,3420,2005,2524,784,944,1610,1155,2628,495,270,767,462,947,998,2222,55,977,1863,2276,17,1463,1061,860,426,2227,2319,1062,2321,613 | 0.45059639260802203,2.1629094522490995,3.330675073412696,-1.1173081574095296,0.5728687985988167,1.4850830339872365,0.1930659788602032,1.454160780076086,-0.2298275615859757,-0.036040615240763116,0.34547107923826165,1.2126492640347504,2.4593413890789497,0.0802551137654914,0.9526587487920226,0.6716892768089571,3.8776383909815935,1.5460733812057033,-0.46011072625306215,-0.38183149261829497,0.17077418478294684,0.2152252789325902,1.278766009486297,1.5004365612200485,-0.156005530653432,1.3113456984812744,-0.33050110950497374,0.4712633310682175,0.8798988183330019,0.034165029853640824,-1.3730037178018255,-0.7328149058045688,-1.8981680975823387,0.2152252789325902,-0.4077515144924765,-0.2298275615859757,-0.7896574082543483,-0.5399768938790059,0.49181353408407796,-0.7046914435829653,0.0802551137654914,-0.2798379365454374,0.32407975809190903,0.6911303718588904,0.8429440113127525,0.2152252789325902,-0.059733927382445505,-0.10756689934795993,0.3878839297734311,-0.38183149261829497,1.5004365612200485,1.8898302095929331,1.391439557045039,2.1877114381475624,0.034165029853640824,1.1959167885724808,0.28092127296462205,0.5122481028192044,-0.2298275615859757,0.4712633310682175,0.32407975809190903,-0.4338439486214293,2.55930399160172,-0.156005530653432,0.9526587487920226,-0.10756689934795993,-1.7159402967452053,0.6716892768089571,-0.7328149058045688,-1.861111139387871,-0.2298275615859757,-0.48655380913412877,0.4712633310682175,0.34547107923826165,-0.036040615240763116,0.1930659788602032,-0.5399768938790059,0.8614700219449289,1.3755732121053947,0.49181353408407796,0.9526587487920226,0.34547107923826165,0.3025635649487059,-0.33050110950497374,2.800347105622523,0.32407975809190903,-0.156005530653432,-0.35608198164205196,3.6146577554616006,0.034165029853640824,0.25915163831136523,0.4089078305742396,1.0062486792449554,-0.33050110950497374,-0.38183149261829497,0.25915163831136523,-0.38183149261829497,0.6911303718588904 | 3,477 |
Nadh dehydrogenase complex assembly | 16 | 31 | 2.820807 | 0.00479 | O43920,O95168,Q9Y375,Q15070,Q86Y39,Q8N183,Q96CU9,O75306,Q9NX14,Q16795,O96000,Q9H061,O95169,Q9Y6M9,O43676,P03886 | Processes and pathways | GO Biological process | msigdb_gobp | 634,411,426,10,331,738,78,238,767,502,618,56,89,613,27,218 | 844,27,3236,634,1124,238,1572,411,89,1329,618,218,2442,3346,750,10,3129,502,331,738,971,78,2524,56,1155,767,947,998,1863,426,613 | 0.4089078305742396,3.330675073412696,-1.1173081574095296,0.6521418328596066,0.1930659788602032,1.454160780076086,-0.036040615240763116,1.0239295819857912,2.4593413890789497,0.0802551137654914,0.6716892768089571,1.5460733812057033,-0.46011072625306215,-1.3730037178018255,0.49181353408407796,3.7388244635191787,-0.9353499504290953,0.8429440113127525,1.1959167885724808,0.5122481028192044,0.32407975809190903,2.55930399160172,-0.48655380913412877,2.7801609678496,0.1930659788602032,0.49181353408407796,0.34547107923826165,0.3025635649487059,-0.156005530653432,1.0062486792449554,0.6911303718588904 | 3,477 |
Steroid metabolism | 11 | 28 | 2.818842 | 0.00482 | Q9UBM7,P04062,P37268,Q14739,Q15800,O76062,O15118,Q15392,Q15125,P04035,O75845 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 227,70,39,107,76,77,113,114,406,185,286 | 113,730,286,77,815,1331,185,70,747,2978,2449,39,2903,583,3078,2987,3357,107,406,3042,114,962,76,415,2573,227,1461,1422 | 2.2000380350552113,0.5122481028192044,1.3113456984812744,2.55930399160172,0.42981160276593183,0.0802551137654914,1.708173559202872,2.6134173692391474,0.49181353408407796,-0.7896574082543483,-0.46011072625306215,3.114311106742357,-0.7328149058045688,0.7104660844148053,-0.8764458292816217,-0.7896574082543483,-1.4060856588926407,2.284966007398189,1.0415205771938503,-0.8473098246926763,2.1877114381475624,0.32407975809190903,2.5702062195920785,1.0239295819857912,-0.5131751901331499,1.5157190967783831,0.034165029853640824,0.057280464510361444 | 3,477 |
Glycosphingolipid metabolic process | 6 | 10 | 2.812225 | 0.00492 | P06865,P04062,Q16739,P06280,P16278,Q99805 | Processes and pathways | GO Biological process | msigdb_gobp | 292,70,72,239,50,150 | 70,239,292,1873,50,310,1306,517,72,150 | 2.6134173692391474,1.454160780076086,1.2950952054305622,-0.18045600562004682,2.8600703081678036,1.2458689372071072,0.10309040916855126,0.8243199236689244,2.6026737590356976,1.9437070526815678 | 3,477 |
Sphingolipid metabolism overview | 7 | 9 | 2.812079 | 0.004922 | O15121,Q96G23,Q16739,Q13510,Q06136,P27544,O95470 | Processes and pathways | WikiPathways | msigdb_wp | 321,289,72,75,83,60,94 | 321,410,1003,94,60,83,75,72,289 | 1.2126492640347504,1.0239295819857912,0.28092127296462205,2.4138173556309015,2.7187441900095033,2.5041837894887355,2.5702062195920785,2.6026737590356976,1.3113456984812744 | 3,477 |
Golgi stack | 18 | 37 | 2.807271 | 0.004996 | Q8N6G5,O00461,Q10713,Q8WVQ1,Q8NBN3,Q99523,Q15363,Q8TBA6,Q8WVM8,P51572,Q10472,Q9H4A6,Q14789,Q8NBZ7,Q96L58,O95249,P98194,Q08379 | Localization | GO Cellular component | msigdb_gocc | 126,161,600,355,326,554,73,299,684,582,271,765,625,504,148,180,183,754 | 161,2186,180,953,1626,1784,582,1184,183,2408,777,754,1831,1137,271,600,625,2300,73,2835,126,326,504,299,684,355,148,554,3109,2307,765,948,2376,1921,2931,1464,892 | 1.8350245833383434,-0.33050110950497374,1.7367975316840694,0.32407975809190903,-0.059733927382445505,-0.13170970617137487,0.7104660844148053,0.17077418478294684,1.7225172205843342,-0.4338439486214293,0.4712633310682175,0.49181353408407796,-0.156005530653432,0.1930659788602032,1.3596312630979113,0.6911303718588904,0.6716892768089571,-0.38183149261829497,2.5918908586909555,-0.67676342294761,2.112700849689168,1.2126492640347504,0.8429440113127525,1.278766009486297,0.592851555040084,1.145220634988901,1.9570342209689406,0.7678504081670597,-0.9057916890941692,-0.38183149261829497,0.49181353408407796,0.34547107923826165,-0.4077515144924765,-0.18045600562004682,-0.7328149058045688,0.034165029853640824,0.3878839297734311 | 3,477 |
Protein transmembrane import into intracellular organelle | 8 | 12 | 2.803965 | 0.005048 | O60830,Q99595,O14925,Q15388,O43615,O96008,O95831,O75381 | Processes and pathways | GO Biological process | msigdb_gobp | 0,1,101,422,386,455,454,365 | 101,386,0,365,745,454,455,1929,422,552,1,886 | 2.3206535481076274,1.076435891103936,4.729861486365382,1.1110006232313312,0.49181353408407796,0.9526587487920226,0.9526587487920226,-0.20506278845667675,1.0062486792449554,0.7678504081670597,4.593322988469487,0.3878839297734311 | 3,477 |
Abnormal tissue metabolite concentration | 7 | 16 | 2.795655 | 0.005179 | Q9NZJ7,P06865,P06280,O75381,P56589,P17900,P07602 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 359,292,239,365,211,310,25 | 926,365,1127,239,292,25,1873,2491,310,464,1183,211,1195,1207,359,1863 | 0.34547107923826165,1.1110006232313312,0.1930659788602032,1.454160780076086,1.2950952054305622,3.363757087870197,-0.18045600562004682,-0.48655380913412877,1.2458689372071072,0.9346103914962526,0.17077418478294684,1.576150205122679,0.17077418478294684,0.17077418478294684,1.145220634988901,-0.156005530653432 | 3,477 |
Steroid biosynthetic process | 17 | 49 | 2.794996 | 0.00519 | Q9UBM7,P16435,Q9BZF3,Q53GQ0,P37268,Q13510,Q15800,O76062,Q14739,P05023,P30536,Q15392,Q15125,Q14534,P04035,Q16850,O75845 | Processes and pathways | GO Biological process | msigdb_gobp | 227,324,133,261,39,75,76,77,107,336,210,114,406,151,185,415,286 | 770,730,286,435,77,815,1331,185,336,3030,747,3392,324,2492,1258,2978,795,210,39,2825,904,2705,2903,2987,75,3357,151,107,3213,406,3042,114,1342,3043,962,76,415,261,586,2572,1048,2573,2110,133,1760,805,227,1918,1422 | 0.4712633310682175,0.5122481028192044,1.3113456984812744,0.9706140497703232,2.55930399160172,0.42981160276593183,0.0802551137654914,1.708173559202872,1.1791016511727834,-0.8473098246926763,0.49181353408407796,-1.5754619965695265,1.2126492640347504,-0.48655380913412877,0.12578776192278873,-0.7896574082543483,0.45059639260802203,1.576150205122679,3.114311106742357,-0.67676342294761,0.3667387385449585,-0.594129530873194,-0.7328149058045688,-0.7896574082543483,2.5702062195920785,-1.4060856588926407,1.916883074110937,2.284966007398189,-1.05575948254301,1.0415205771938503,-0.8473098246926763,2.1877114381475624,0.0802551137654914,-0.8473098246926763,0.32407975809190903,2.5702062195920785,1.0239295819857912,1.391439557045039,0.7104660844148053,-0.5131751901331499,0.25915163831136523,-0.5131751901331499,-0.2798379365454374,2.048777722930143,-0.10756689934795993,0.45059639260802203,1.5157190967783831,-0.18045600562004682,0.057280464510361444 | 3,477 |
Myoclonus | 24 | 95 | 2.792422 | 0.005232 | P05067,P00846,O95630,Q9NWS8,P50897,P07602,O75845,O14773,Q9UBX3,O75503,Q96AA3,P00374,P27544,Q01105,Q9Y4G8,P04062,Q14108,Q13510,O96008,Q96CU9,P03886,Q9NQZ5,Q9NZJ7,P13073 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 132,8,389,270,20,25,286,291,55,57,444,188,60,316,194,70,71,75,455,78,218,222,359,228 | 791,2933,291,1323,3091,57,286,2235,389,455,188,619,8,218,2442,70,3157,132,25,773,228,1974,662,2335,60,3013,2901,1528,1436,2497,1031,1782,2787,3099,2984,2452,20,1096,3073,2869,1884,1829,1731,1481,2793,316,1338,2707,2831,3145,600,2601,2148,2556,75,870,71,2045,2607,2461,3166,1793,1645,1545,969,1148,781,1498,444,78,1953,882,2165,3351,1847,2106,3410,1413,2167,2524,3400,1656,1657,495,222,1700,270,359,55,2317,2480,1247,194,809,3297 | 0.45059639260802203,-0.7611361133509404,1.2950952054305622,0.0802551137654914,-0.9057916890941692,2.7598328946941053,1.3113456984812744,-0.35608198164205196,1.076435891103936,0.9526587487920226,1.6792942904532233,0.6716892768089571,3.8776383909815935,1.5460733812057033,-0.46011072625306215,2.6134173692391474,-0.9951140817015471,2.0616675699999085,3.363757087870197,0.4712633310682175,1.5004365612200485,-0.2298275615859757,0.6127239700105706,-0.4077515144924765,2.7187441900095033,-0.8183811716642784,-0.7328149058045688,-0.01249402587824863,0.034165029853640824,-0.48655380913412877,0.25915163831136523,-0.13170970617137487,-0.6490285776513719,-0.9057916890941692,-0.7896574082543483,-0.46011072625306215,3.4447291832381413,0.2152252789325902,-0.8764458292816217,-0.7046914435829653,-0.18045600562004682,-0.156005530653432,-0.10756689934795993,0.010907357520276812,-0.6490285776513719,1.229299756524913,0.0802551137654914,-0.594129530873194,-0.67676342294761,-0.9651232031602808,0.6911303718588904,-0.5399768938790059,-0.3050870328676839,-0.5131751901331499,2.5702062195920785,0.3878839297734311,2.6134173692391474,-0.2547520329568809,-0.5399768938790059,-0.46011072625306215,-0.9951140817015471,-0.13170970617137487,-0.059733927382445505,-0.01249402587824863,0.32407975809190903,0.1930659788602032,0.4712633310682175,0.010907357520276812,0.9706140497703232,2.55930399160172,-0.20506278845667675,0.3878839297734311,-0.3050870328676839,-1.3730037178018255,-0.156005530653432,-0.2798379365454374,-1.7159402967452053,0.057280464510361444,-0.3050870328676839,-0.48655380913412877,-1.6101555780664825,-0.059733927382445505,-0.059733927382445505,0.8614700219449289,1.5309311892284372,-0.08357550145023511,1.3755732121053947,1.145220634988901,2.800347105622523,-0.38183149261829497,-0.46011072625306215,0.1483485632559681,1.650155885127456,0.45059639260802203,-1.2113748690313957 | 3,477 |
Mitochondrial calcium ion transport | 12 | 16 | 2.791311 | 0.005249 | Q9Y277,Q10713,P45880,Q99623,Q8IYU8,Q8NE86,P21796,O95202,P35232,Q9UJZ1,Q8WWC4,Q9BPX6 | Processes and pathways | Reactome Pathways | msigdb_reactome | 196,600,4,393,134,683,18,177,720,576,476,255 | 1169,177,18,720,4,600,134,683,476,2212,943,393,255,576,196,809 | 0.17077418478294684,1.7510149601511857,3.5310561932023865,0.5325681239141068,4.047418142685448,0.6911303718588904,2.0358345353142644,0.592851555040084,0.8982312526302684,-0.33050110950497374,0.34547107923826165,1.076435891103936,1.4072308970681886,0.7296973686019401,1.6354882839084601,0.45059639260802203 | 3,477 |
Sterol biosynthetic process | 12 | 27 | 2.786207 | 0.005333 | Q9UBM7,P16435,P37268,Q14739,Q15800,O76062,Q15392,Q15125,Q14534,P04035,Q16850,O75845 | Processes and pathways | GO Biological process | msigdb_gobp | 227,324,39,107,76,77,114,406,151,185,415,286 | 730,286,435,77,815,1331,185,3030,747,324,39,2825,904,2705,2903,2987,3357,151,107,406,3042,114,962,76,415,227,1422 | 0.5122481028192044,1.3113456984812744,0.9706140497703232,2.55930399160172,0.42981160276593183,0.0802551137654914,1.708173559202872,-0.8473098246926763,0.49181353408407796,1.2126492640347504,3.114311106742357,-0.67676342294761,0.3667387385449585,-0.594129530873194,-0.7328149058045688,-0.7896574082543483,-1.4060856588926407,1.916883074110937,2.284966007398189,1.0415205771938503,-0.8473098246926763,2.1877114381475624,0.32407975809190903,2.5702062195920785,1.0239295819857912,1.5157190967783831,0.057280464510361444 | 3,477 |
Cation channel activity | 12 | 20 | 2.782596 | 0.005393 | P56134,Q9P246,O75947,P06576,P36542,P00846,Q8NE86,O75964,Q9UM00,P24539,P56385,Q4KMQ2 | Functions | GO Molecular function | msigdb_gomf | 734,395,814,731,817,8,683,19,612,277,279,416 | 814,19,8,731,1576,2394,277,1434,817,1782,1302,734,279,849,1890,416,683,2058,395,612 | 0.42981160276593183,3.468551690459964,3.8776383909815935,0.5122481028192044,-0.036040615240763116,-0.4338439486214293,1.34361310413227,0.034165029853640824,0.42981160276593183,-0.13170970617137487,0.10309040916855126,0.5122481028192044,1.34361310413227,0.4089078305742396,-0.18045600562004682,1.0239295819857912,0.592851555040084,-0.2547520329568809,1.076435891103936,0.6911303718588904 | 3,477 |
Steroid biosynthesis | 10 | 23 | 2.782103 | 0.005401 | Q9UBM7,P37268,Q53GQ0,Q14739,Q15800,O76062,Q15392,Q15125,P04035,O75845 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 227,39,261,107,76,77,114,406,185,286 | 286,77,1331,185,747,39,904,2903,2987,3357,107,406,3042,114,962,76,415,261,586,2110,1760,227,1422 | 1.3113456984812744,2.55930399160172,0.0802551137654914,1.708173559202872,0.49181353408407796,3.114311106742357,0.3667387385449585,-0.7328149058045688,-0.7896574082543483,-1.4060856588926407,2.284966007398189,1.0415205771938503,-0.8473098246926763,2.1877114381475624,0.32407975809190903,2.5702062195920785,1.0239295819857912,1.391439557045039,0.7104660844148053,-0.2798379365454374,-0.10756689934795993,1.5157190967783831,0.057280464510361444 | 3,477 |
Cherry red spot of the macula | 6 | 9 | 2.773269 | 0.00555 | P10619,P06865,Q13510,P16278,P17900,P07602 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 192,292,75,50,310,25 | 292,25,1873,192,2446,50,310,75,359 | 1.2950952054305622,3.363757087870197,-0.18045600562004682,1.650155885127456,-0.46011072625306215,2.8600703081678036,1.2458689372071072,2.5702062195920785,1.145220634988901 | 3,477 |
Golgi associated vesicle | 6 | 34 | 2.77146 | 0.005581 | P05067,P24390,Q15363,Q9Y3B3,Q8N511,O43731 | Localization | GO Cellular component | msigdb_gocc | 132,7,73,146,51,22 | 1813,22,2386,2391,132,2938,2283,846,7,1877,2451,2137,404,2947,2870,2871,2454,1184,1135,1136,2793,2408,73,51,1109,193,684,554,1239,2311,1665,2314,146,1768 | -0.156005530653432,3.396438992453167,-0.4338439486214293,-0.4338439486214293,2.0616675699999085,-0.7611361133509404,-0.38183149261829497,0.4089078305742396,3.9311110989059386,-0.18045600562004682,-0.46011072625306215,-0.3050870328676839,1.0415205771938503,-0.7611361133509404,-0.7046914435829653,-0.7046914435829653,-0.46011072625306215,0.17077418478294684,0.1930659788602032,0.1930659788602032,-0.6490285776513719,-0.4338439486214293,2.5918908586909555,2.8600703081678036,0.2152252789325902,1.650155885127456,0.592851555040084,0.7678504081670597,0.1483485632559681,-0.38183149261829497,-0.059733927382445505,-0.38183149261829497,1.970305373246249,-0.10756689934795993 | 3,477 |
Glycoprotein biosynthetic process | 24 | 57 | 2.768022 | 0.00564 | Q8N6G5,Q7LGA3,Q10472,O60762,O14734,Q9H9S5,Q99805,Q8TCJ2,Q96L58,Q9Y5P6,Q9H0U3,Q96AA3,Q96IZ0,Q9NQX7,Q92542,Q9BT22,Q8NCH0,Q8WVQ1,Q9Y673,O60502,Q9H4A6,O15118,P46977,Q08379 | Processes and pathways | GO Biological process | msigdb_gobp | 126,391,271,772,770,283,150,669,148,810,688,444,715,334,356,226,100,355,633,110,765,113,497,754 | 2075,770,113,2183,1430,110,1969,3114,772,2935,2539,2235,794,1172,2030,2449,1093,497,867,1940,1305,2599,754,1831,1137,271,938,1191,2835,1194,1544,2158,2254,391,1016,1018,126,100,669,355,356,444,715,148,150,226,688,946,765,283,334,1159,2771,948,2677,810,633 | -0.2798379365454374,0.4712633310682175,2.2000380350552113,-0.33050110950497374,0.034165029853640824,2.2123154767354705,-0.2298275615859757,-0.9353499504290953,0.4712633310682175,-0.7611361133509404,-0.5131751901331499,-0.35608198164205196,0.45059639260802203,0.17077418478294684,-0.2547520329568809,-0.46011072625306215,0.2152252789325902,0.8429440113127525,0.3878839297734311,-0.20506278845667675,0.10309040916855126,-0.5399768938790059,0.49181353408407796,-0.156005530653432,0.1930659788602032,1.3596312630979113,0.34547107923826165,0.17077418478294684,-0.67676342294761,0.17077418478294684,-0.01249402587824863,-0.3050870328676839,-0.35608198164205196,1.076435891103936,0.28092127296462205,0.28092127296462205,2.112700849689168,2.332456969422599,0.6127239700105706,1.145220634988901,1.145220634988901,0.9706140497703232,0.5527746697318787,1.9570342209689406,1.9437070526815678,1.5157190967783831,0.592851555040084,0.34547107923826165,0.49181353408407796,1.34361310413227,1.1959167885724808,0.1930659788602032,-0.6214846781566223,0.34547107923826165,-0.5669609774156144,0.45059639260802203,0.6716892768089571 | 3,477 |
Ectopic calcification | 17 | 62 | 2.766842 | 0.00566 | Q9UBM7,P05067,P04062,Q16625,Q14739,O60313,P38435,P35670,P23786,P38571,P56589,O75381,Q15125,O75844,P03886,O00116,O75845 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 227,132,70,260,107,234,143,203,49,304,211,365,406,62,218,340,286 | 340,2122,528,615,2636,234,2388,3308,365,1088,2734,62,286,1089,1127,619,1378,218,2442,70,132,2692,1625,1470,659,773,2286,1217,2587,49,2030,203,143,304,464,2240,1183,956,1828,1884,796,211,2148,909,107,3259,406,962,260,1313,1547,2421,3215,1750,2062,2476,2723,2222,227,2228,3179,3297 | 1.1622031649520077,-0.3050870328676839,0.8055968854608062,0.6716892768089571,-0.5669609774156144,1.4850830339872365,-0.4338439486214293,-1.2752831992039835,1.1110006232313312,0.2152252789325902,-0.6214846781566223,2.6979801115679907,1.3113456984812744,0.2152252789325902,0.1930659788602032,0.6716892768089571,0.057280464510361444,1.5460733812057033,-0.46011072625306215,2.6134173692391474,2.0616675699999085,-0.594129530873194,-0.059733927382445505,0.010907357520276812,0.6127239700105706,0.4712633310682175,-0.38183149261829497,0.1483485632559681,-0.5399768938790059,2.87970497361229,-0.2547520329568809,1.591085893413555,1.9835209030925693,1.2623574695593112,0.9346103914962526,-0.35608198164205196,0.17077418478294684,0.32407975809190903,-0.156005530653432,-0.18045600562004682,0.45059639260802203,1.576150205122679,-0.3050870328676839,0.3667387385449585,2.284966007398189,-1.1484283110266162,1.0415205771938503,0.32407975809190903,1.391439557045039,0.10309040916855126,-0.01249402587824863,-0.4338439486214293,-1.05575948254301,-0.10756689934795993,-0.2547520329568809,-0.46011072625306215,-0.594129530873194,-0.33050110950497374,1.5157190967783831,-0.33050110950497374,-0.9951140817015471,-1.2113748690313957 | 3,477 |
calmodulin-related | 8 | 13 | 2.766229 | 0.005671 | P80303,Q8IYU8,P0DP25,P41208,Q02818,Q14257,Q9BRK5,Q9BPX6 | Functions | Panther Protein class | panther_protein_class | 9,134,106,108,46,144,275,255 | 322,106,2697,3432,108,9,46,144,637,134,2059,255,275 | 1.2126492640347504,2.284966007398189,-0.594129530873194,-1.973229675892529,2.2609401999561145,3.864091853987292,3.0041326496319325,1.9835209030925693,0.6521418328596066,2.0358345353142644,-0.2547520329568809,1.4072308970681886,1.3596312630979113 | 3,477 |
Golgi apparatus | 107 | 337 | 2.76449 | 0.005701 | P24390,P80303,P50897,O43731,O00429,Q9Y282,Q9UP83,Q99523,Q16799,Q02818,P16278,Q9UJG1,O75503,Q9Y5Z9,Q8IZA0,O95197,Q7Z6M1,P04062,Q14108,Q16739,Q15363,Q96S66,Q86Y82,P51572,Q9UM00,Q8NEW0,Q8TB61,Q8NCH0,Q10713,Q14789,P20337,O15118,P01889,Q15392,Q8N4V1,Q6ZRP7,Q8N6G5,Q8NEY8,Q9UBF8,P05067,Q9P2W9,P40616,O15258,Q9BTU6,Q9Y3B3,Q96L58,Q99805,Q93050,Q8IV08,O00400,O00461,P51790,Q9UQ16,Q9UNK0,Q8WVM8,O60499,O95070,O95249,P98194,P35670,O15127,Q96A57,P52292,P06280,Q7Z3C6,Q9H7Z7,Q9BUR5,Q10472,Q9BRK5,Q9H9S5,O14773,P35613,Q8TBA6,Q9UNK9,Q9NX40,Q14CX7,O43852,Q8NBN3,Q9NQX7,P05023,Q6NUQ4,Q9UQB8,Q92542,Q8WVQ1,P25054,Q9NTJ5,Q9Y3A6,Q7Z3D4,Q7LGA3,Q6NTF9,Q8NF37,P49755,Q96RL7,Q9UI14,P20340,Q12907,O15260,Q92544,Q9Y5X1,Q96M27,Q969E2,P10321,Q9H0U4,P46934,Q92845,Q92896,Q8NBZ7 | Localization | GO Cellular component | msigdb_gocc | 7,9,20,22,528,24,549,554,42,46,50,575,57,59,568,63,67,70,71,72,73,589,584,582,612,90,95,100,600,625,621,113,620,114,122,639,126,648,654,132,140,645,643,672,146,148,150,153,157,160,161,166,691,690,684,169,175,180,183,203,209,231,237,239,253,256,264,271,275,283,291,296,299,301,307,318,322,326,334,336,345,350,356,355,373,394,396,392,391,390,403,404,408,418,419,438,433,466,467,478,477,473,489,482,494,505,504 | 1000,1427,2180,1515,160,528,1769,161,1813,2816,1002,2181,2324,291,2230,813,2182,1620,113,1168,209,643,433,1712,2385,3373,1430,2184,22,2386,2731,897,322,169,1969,2732,2126,2186,2640,952,57,2583,2975,2441,175,63,1327,180,1328,1575,1064,746,2391,620,70,953,336,132,239,1816,901,816,1380,2938,2283,1626,473,773,846,50,902,3120,1381,621,419,1579,3300,2897,2492,1778,7,373,3387,2290,2783,2591,2822,1780,2192,1932,1877,296,203,2134,2699,645,1007,2787,1784,482,2137,3408,1261,1182,404,2401,1095,1220,20,2140,2947,582,166,678,237,2791,1265,2870,2871,956,796,2551,2243,2454,905,735,1184,1135,1136,1186,1336,2246,9,1940,2041,183,2793,2408,2907,46,869,777,754,1189,1831,1137,271,2354,600,1138,2909,438,2751,908,1339,1068,851,937,2558,1396,1944,1984,2358,71,2606,1192,1897,625,2754,2359,318,2048,2300,73,1142,114,1488,912,2835,72,42,1271,3166,1491,390,345,3416,1794,2836,2209,639,3104,391,2613,253,392,2256,1232,67,2913,2418,2914,584,1600,157,2160,568,1407,122,126,1233,1278,1995,326,504,100,2519,1109,90,648,403,95,299,1998,1948,3132,684,355,1448,2001,356,466,1355,494,505,2213,153,477,3326,713,724,1042,231,2060,3133,148,478,1360,408,589,1048,554,1075,2167,150,3109,2307,3361,275,1454,918,672,1208,264,1239,3362,1609,1851,2308,3263,3400,489,2309,1556,1760,2171,765,256,3384,283,2967,2311,922,334,3195,1507,2114,394,307,1119,1509,1159,1664,1665,948,140,2314,654,2677,418,2174,575,2972,1120,2850,1764,2376,2071,612,2851,690,301,1921,549,1026,691,350,2225,1708,24,2931,1767,1811,860,3198,1669,1464,396,146,3024,3334,861,467,59,1768,892,2437 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| 3,477 |
Cis golgi network | 8 | 17 | 2.764304 | 0.005704 | O00461,Q9Y3A6,P24390,Q8TBA6,Q9UNK9,O95249,P98194,O43731 | Localization | GO Cellular component | msigdb_gocc | 161,396,7,299,301,180,183,22 | 161,2184,22,180,7,1780,404,183,754,625,2835,299,684,2001,2307,301,396 | 1.8350245833383434,-0.33050110950497374,3.396438992453167,1.7367975316840694,3.9311110989059386,-0.13170970617137487,1.0415205771938503,1.7225172205843342,0.49181353408407796,0.6716892768089571,-0.67676342294761,1.278766009486297,0.592851555040084,-0.2298275615859757,-0.38183149261829497,1.278766009486297,1.076435891103936 | 3,477 |
Dysphagia | 28 | 141 | 2.756562 | 0.005841 | P05067,Q9NR77,P00846,Q99720,Q96D71,P07602,Q9UHX1,P12235,P35637,Q01105,P04062,Q14108,Q15067,Q13510,P35670,P21912,O95169,Q03164,O76024,P03886,Q9NZJ7,Q14739,O60313,P15586,O75306,O15118,Q9HD42,O95155 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 132,265,8,16,274,25,36,295,311,316,70,71,200,75,203,202,89,344,341,218,359,107,234,366,238,113,383,372 | 528,2933,2231,113,2856,694,234,1715,1521,238,1572,1523,863,341,815,2689,372,89,1328,2893,8,620,218,2442,70,132,1720,25,3064,2645,3065,3321,295,366,1332,2649,2396,847,2650,202,2288,2898,3346,3035,2901,311,203,1031,2451,1094,2787,1301,1881,1096,1533,2828,1478,664,3100,1884,2141,3393,583,3226,1731,516,1887,2793,316,344,2409,2707,2831,2599,2353,1308,3145,1189,2601,1733,1035,75,71,1309,2045,2561,2461,107,200,2664,1036,502,2253,1313,2209,1545,1275,1597,3405,568,486,738,1601,1202,1996,829,940,274,3246,1847,1848,408,3410,2262,1413,2167,2573,16,3170,1455,2524,1908,2923,1283,383,265,741,3090,2271,359,653,3060,888,977,36,1287,1026,2177,2276,1061,809 | 0.8055968854608062,-0.7611361133509404,-0.35608198164205196,2.2000380350552113,-0.7046914435829653,0.5728687985988167,1.4850830339872365,-0.10756689934795993,-0.01249402587824863,1.454160780076086,-0.036040615240763116,-0.01249402587824863,0.3878839297734311,1.1622031649520077,0.42981160276593183,-0.594129530873194,1.093761710301451,2.4593413890789497,0.0802551137654914,-0.7328149058045688,3.8776383909815935,0.6716892768089571,1.5460733812057033,-0.46011072625306215,2.6134173692391474,2.0616675699999085,-0.10756689934795993,3.363757087870197,-0.8764458292816217,-0.5669609774156144,-0.8764458292816217,-1.307605772494711,1.278766009486297,1.1110006232313312,0.0802551137654914,-0.5669609774156144,-0.4338439486214293,0.4089078305742396,-0.5669609774156144,1.591085893413555,-0.38183149261829497,-0.7328149058045688,-1.3730037178018255,-0.8473098246926763,-0.7328149058045688,1.2458689372071072,1.591085893413555,0.25915163831136523,-0.46011072625306215,0.2152252789325902,-0.6490285776513719,0.10309040916855126,-0.18045600562004682,0.2152252789325902,-0.01249402587824863,-0.67676342294761,0.010907357520276812,0.6127239700105706,-0.9057916890941692,-0.18045600562004682,-0.3050870328676839,-1.5754619965695265,0.7104660844148053,-1.0864195054268886,-0.10756689934795993,0.8243199236689244,-0.18045600562004682,-0.6490285776513719,1.229299756524913,1.1622031649520077,-0.4338439486214293,-0.594129530873194,-0.67676342294761,-0.5399768938790059,-0.4077515144924765,0.10309040916855126,-0.9651232031602808,0.17077418478294684,-0.5399768938790059,-0.10756689934795993,0.25915163831136523,2.5702062195920785,2.6134173692391474,0.10309040916855126,-0.2547520329568809,-0.5131751901331499,-0.46011072625306215,2.284966007398189,1.6059537940917206,-0.5669609774156144,0.25915163831136523,0.8429440113127525,-0.35608198164205196,0.10309040916855126,-0.33050110950497374,-0.01249402587824863,0.12578776192278873,-0.036040615240763116,-1.6803908431345842,0.7296973686019401,0.8798988183330019,0.5122481028192044,-0.036040615240763116,0.17077418478294684,-0.2298275615859757,0.42981160276593183,0.34547107923826165,1.3596312630979113,-1.1173081574095296,-0.156005530653432,-0.156005530653432,1.0415205771938503,-1.7159402967452053,-0.35608198164205196,0.057280464510361444,-0.3050870328676839,-0.5131751901331499,3.6370039877820517,-0.9951140817015471,0.034165029853640824,-0.48655380913412877,-0.18045600562004682,-0.7328149058045688,0.12578776192278873,1.093761710301451,1.391439557045039,0.5122481028192044,-0.8764458292816217,-0.35608198164205196,1.145220634988901,0.6324870611210252,-0.8473098246926763,0.3878839297734311,0.32407975809190903,3.1678099470628176,0.12578776192278873,0.28092127296462205,-0.3050870328676839,-0.35608198164205196,0.25915163831136523,0.45059639260802203 | 3,477 |
Nuclear inner membrane | 10 | 23 | 2.756361 | 0.005845 | Q9UH99,P62995,P50402,Q14739,O76062,Q5SNT2,Q99720,Q9H1E5,Q8IXM6,O75844 | Localization | GO Cellular component | msigdb_gocc | 258,646,551,107,77,626,16,81,312,62 | 62,77,793,847,1094,1301,551,3303,646,1338,1392,1440,107,1595,626,312,2055,2572,16,1208,81,258,693 | 2.6979801115679907,2.55930399160172,0.45059639260802203,0.4089078305742396,0.2152252789325902,0.10309040916855126,0.7678504081670597,-1.2432072777509597,0.6324870611210252,0.0802551137654914,0.057280464510361444,0.034165029853640824,2.284966007398189,-0.036040615240763116,0.6716892768089571,1.2458689372071072,-0.2547520329568809,-0.5131751901331499,3.6370039877820517,0.17077418478294684,2.526354693612427,1.4072308970681886,0.592851555040084 | 3,477 |
Serine hydrolase activity | 11 | 20 | 2.753064 | 0.005904 | P10619,O43464,P42785,Q6PIU2,O14773,O75976,Q6NTF9,Q9H3G5,Q16740,P67812,Q9HB40 | Functions | GO Molecular function | msigdb_gomf | 192,539,35,441,291,509,390,207,48,181,23 | 291,539,509,192,2778,2942,1823,35,3123,1388,956,181,48,1271,638,390,441,1147,207,23 | 1.2950952054305622,0.7867740121764749,0.8243199236689244,1.650155885127456,-0.6490285776513719,-0.7611361133509404,-0.156005530653432,3.1678099470628176,-0.9353499504290953,0.057280464510361444,0.32407975809190903,1.7367975316840694,2.928209016421231,0.12578776192278873,0.6521418328596066,1.076435891103936,0.9706140497703232,0.1930659788602032,1.591085893413555,3.388305582650849 | 3,477 |
Macromolecule transmembrane transporter activity | 11 | 13 | 2.75257 | 0.005913 | O94826,Q99595,Q9UGP8,O60830,O14925,Q9NS69,Q15388,O96008,P51991,P49755,Q07820 | Functions | GO Molecular function | msigdb_gomf | 745,1,716,0,101,6,422,455,751,404,776 | 1427,101,0,745,455,404,751,849,776,422,1,6,716 | 0.034165029853640824,2.3206535481076274,4.729861486365382,0.49181353408407796,0.9526587487920226,1.0415205771938503,0.49181353408407796,0.4089078305742396,0.4712633310682175,1.0062486792449554,4.593322988469487,4.015650297766216,0.5527746697318787 | 3,477 |
Nucleotide transport | 10 | 15 | 2.751052 | 0.00594 | O00400,P41440,Q9HC21,P12235,Q9BSK2,P05141,Q9H2D1,P12236,Q6NUK1,Q8TB61 | Processes and pathways | GO Biological process | msigdb_gobp | 160,224,425,295,327,511,82,276,440,95 | 160,771,1123,511,295,276,224,542,440,3082,95,855,327,82,425 | 1.8625451660048729,0.4712633310682175,0.1930659788602032,0.8243199236689244,1.278766009486297,1.34361310413227,1.5157190967783831,0.7867740121764749,0.9706140497703232,-0.8764458292816217,2.4023277992997625,0.4089078305742396,1.2126492640347504,2.51528988241545,1.0062486792449554 | 3,477 |
Protein transmembrane transporter activity | 6 | 12 | 2.749636 | 0.005966 | O60830,Q99595,O14925,Q9NS69,Q15388,P49755 | Functions | GO Molecular function | msigdb_gomf | 0,1,101,6,422,404 | 1427,101,0,745,455,404,849,776,422,1,6,716 | 0.034165029853640824,2.3206535481076274,4.729861486365382,0.49181353408407796,0.9526587487920226,1.0415205771938503,0.4089078305742396,0.4712633310682175,1.0062486792449554,4.593322988469487,4.015650297766216,0.5527746697318787 | 3,477 |
Inorganic anion transmembrane transporter activity | 9 | 23 | 2.746109 | 0.006031 | Q9Y277,P45880,P51790,Q15043,Q9C0H2,P21796,Q9UBX3,Q5T3U5,P51798 | Functions | GO Molecular function | msigdb_gomf | 196,4,166,198,14,18,55,125,343 | 3220,771,926,1252,1626,18,866,4,166,343,664,934,198,416,125,736,3082,589,836,14,55,196,3307 | -1.0864195054268886,0.4712633310682175,0.34547107923826165,0.12578776192278873,-0.059733927382445505,3.5310561932023865,0.3878839297734311,4.047418142685448,1.8072650329398752,1.1622031649520077,0.6127239700105706,0.34547107923826165,1.6207544213461318,1.0239295819857912,2.112700849689168,0.5122481028192044,-0.8764458292816217,0.7104660844148053,0.42981160276593183,3.644410503961847,2.800347105622523,1.6354882839084601,-1.2432072777509597 | 3,477 |
Alpha/Beta hydrolase fold [IPR029058] | 13 | 27 | 2.737109 | 0.006198 | P10619,Q9UMR5,P42785,Q6PIU2,P07099,Q9H3G5,P38571,P50897,Q9NUJ1,Q9HB40,Q8NCG7,Q8NCC3,Q9H6V9 | Sequence | InterPro Superfamily | interpro_homologous_superfamily | 192,65,35,441,11,207,304,20,213,23,346,58,30 | 3286,11,192,3288,2778,2398,304,35,3123,1182,20,1271,3315,441,1147,459,58,346,3192,3327,3462,207,30,23,213,65,1710 | -1.2113748690313957,3.717339716940446,1.650155885127456,-1.2113748690313957,-0.6490285776513719,-0.4338439486214293,1.2623574695593112,3.1678099470628176,-0.9353499504290953,0.17077418478294684,3.4447291832381413,0.12578776192278873,-1.2752831992039835,0.9706140497703232,0.1930659788602032,0.9526587487920226,2.7598328946941053,1.1622031649520077,-1.0253252659977525,-1.307605772494711,-2.6675908680237392,1.591085893413555,3.3139814467781297,3.388305582650849,1.576150205122679,2.6875423725396095,-0.08357550145023511 | 3,477 |
Respiratory chain | 16 | 35 | 2.731865 | 0.006298 | O95168,Q9UDW1,P22695,Q86Y39,Q96CU9,O75306,P00403,O96000,Q16795,P03886,O95169,Q9Y6M9,Q6DKK2,O14949,O43676,P14927 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 411,66,481,331,78,238,619,618,502,218,89,613,155,120,27,287 | 791,120,844,27,3236,634,1124,238,1970,1572,411,89,3352,1329,618,619,218,2442,1173,287,2191,481,3346,1580,2984,750,3129,502,155,331,78,767,998,66,613 | 0.45059639260802203,2.1629094522490995,0.4089078305742396,3.330675073412696,-1.1173081574095296,0.6521418328596066,0.1930659788602032,1.454160780076086,-0.2298275615859757,-0.036040615240763116,1.0239295819857912,2.4593413890789497,-1.4060856588926407,0.0802551137654914,0.6716892768089571,0.6716892768089571,1.5460733812057033,-0.46011072625306215,0.17077418478294684,1.3113456984812744,-0.33050110950497374,0.8798988183330019,-1.3730037178018255,-0.036040615240763116,-0.7896574082543483,0.49181353408407796,-0.9353499504290953,0.8429440113127525,1.8898302095929331,1.1959167885724808,2.55930399160172,0.49181353408407796,0.3025635649487059,2.677067202689612,0.6911303718588904 | 3,477 |
Protein localization to endoplasmic reticulum | 15 | 36 | 2.731218 | 0.00631 | Q9UGP8,Q9NQC3,Q96HY6,P24390,Q15629,Q15005,O43292,Q99442,O15258,P46379,P61009,Q9H444,P51572,O43731,Q9Y5M8 | Processes and pathways | GO Biological process | msigdb_gobp | 716,131,650,7,40,647,371,629,643,204,515,673,582,22,159 | 1620,643,371,926,22,1214,2936,1928,2861,1630,7,2544,204,1882,582,2453,2551,515,2090,735,849,647,40,874,3168,2001,650,629,2111,673,131,1664,716,999,1165,159 | -0.059733927382445505,0.6324870611210252,1.093761710301451,0.34547107923826165,3.396438992453167,0.1483485632559681,-0.7611361133509404,-0.20506278845667675,-0.7046914435829653,-0.059733927382445505,3.9311110989059386,-0.5131751901331499,1.591085893413555,-0.18045600562004682,0.7104660844148053,-0.46011072625306215,-0.5131751901331499,0.8243199236689244,-0.2798379365454374,0.5122481028192044,0.4089078305742396,0.6324870611210252,3.050568026938457,0.3878839297734311,-0.9951140817015471,-0.2298275615859757,0.6324870611210252,0.6716892768089571,-0.2798379365454374,0.6127239700105706,2.087288708909836,-0.059733927382445505,0.5527746697318787,0.3025635649487059,0.1930659788602032,1.8762169185952062 | 3,477 |
Huntingtons disease | 28 | 84 | 2.73104 | 0.006313 | O43920,P14406,P45880,P00846,P05141,P21796,P12236,P24539,O43676,Q13561,P14927,O95168,P19388,P12235,Q9UDW1,Q9Y277,P21912,O95169,Q9Y6M9,P13073,P22695,O75306,Q07812,P00403,O96000,Q16795,O14949,O14548 | Processes and pathways | KEGG Pathways | msigdb_kegg | 634,2,4,8,511,18,276,277,27,285,287,411,540,295,66,196,202,89,613,228,481,238,517,619,618,502,120,248 | 1515,791,248,120,2125,844,27,3236,634,1124,238,1970,1572,814,2859,411,89,3352,1329,2391,618,619,8,2489,2281,511,731,1173,2938,2283,1298,295,276,228,2,1817,287,1128,3204,540,2191,774,18,202,481,277,2782,1434,3369,3346,644,2901,1580,817,3098,2787,4,1302,2984,750,1532,1828,2347,3016,1787,1830,958,2793,517,2951,2663,285,1309,2300,3129,502,2805,2571,1953,2004,66,923,196,613 | -0.01249402587824863,0.45059639260802203,1.4229478246834266,2.1629094522490995,-0.3050870328676839,0.4089078305742396,3.330675073412696,-1.1173081574095296,0.6521418328596066,0.1930659788602032,1.454160780076086,-0.2298275615859757,-0.036040615240763116,0.42981160276593183,-0.7046914435829653,1.0239295819857912,2.4593413890789497,-1.4060856588926407,0.0802551137654914,-0.4338439486214293,0.6716892768089571,0.6716892768089571,3.8776383909815935,-0.48655380913412877,-0.38183149261829497,0.8243199236689244,0.5122481028192044,0.17077418478294684,-0.7611361133509404,-0.38183149261829497,0.10309040916855126,1.278766009486297,1.34361310413227,1.5004365612200485,4.053723242400452,-0.156005530653432,1.3113456984812744,0.1930659788602032,-1.05575948254301,0.7867740121764749,-0.33050110950497374,0.4712633310682175,3.5310561932023865,1.591085893413555,0.8798988183330019,1.34361310413227,-0.6490285776513719,0.034165029853640824,-1.4730323578408806,-1.3730037178018255,0.6324870611210252,-0.7328149058045688,-0.036040615240763116,0.42981160276593183,-0.9057916890941692,-0.6490285776513719,4.047418142685448,0.10309040916855126,-0.7896574082543483,0.49181353408407796,-0.01249402587824863,-0.156005530653432,-0.4077515144924765,-0.8183811716642784,-0.13170970617137487,-0.156005530653432,0.32407975809190903,-0.6490285776513719,0.8243199236689244,-0.7611361133509404,-0.5669609774156144,1.327518122481294,0.10309040916855126,-0.38183149261829497,-0.9353499504290953,0.8429440113127525,-0.6490285776513719,-0.5131751901331499,-0.20506278845667675,-0.2298275615859757,2.677067202689612,0.3667387385449585,1.6354882839084601,0.6911303718588904 | 3,477 |
Metal ion transport | 41 | 107 | 2.727429 | 0.006383 | Q9P246,Q8IYU8,P21796,O00429,Q02790,P55011,Q4KMQ2,P08195,Q9H0U3,P78417,P02794,O95202,Q9HD20,Q9UJZ1,P98194,O75844,Q9H2J7,Q15043,P02786,Q13586,P20020,P35670,O15173,P05023,P30536,Q8WWC4,Q9UM00,Q8NEW0,Q9Y5Y0,O76024,P0DP25,P46934,O75027,Q07960,P16615,Q07812,Q16795,P62942,Q8N4V1,Q9H9B4,Q9BPX6 | Processes and pathways | GO Biological process | msigdb_gobp | 395,134,18,528,530,664,416,412,688,171,427,177,53,576,183,62,191,198,578,457,329,203,80,336,210,476,612,90,220,341,106,482,364,377,240,517,502,119,122,640,255 | 528,2890,1323,80,1213,3182,2485,364,1125,1169,62,341,177,578,427,1525,336,1297,1468,1576,816,2394,412,106,2084,3030,3031,240,3119,3033,1578,329,3300,18,1382,3312,3369,1820,210,2697,1528,1385,2030,203,3272,2787,1784,482,1387,1095,2872,1009,664,1185,3467,849,1097,119,171,183,1890,2793,530,1634,1308,517,377,3145,2298,2751,1832,3314,457,3040,198,502,416,3130,3360,2712,134,2761,122,683,90,476,2058,2882,1360,2307,255,836,688,191,2009,640,53,395,2677,576,2678,612,2812,950,1865,809,220 | 0.8055968854608062,-0.7328149058045688,0.0802551137654914,2.526354693612427,0.1483485632559681,-1.0253252659977525,-0.48655380913412877,1.1110006232313312,0.1930659788602032,0.17077418478294684,2.6979801115679907,1.1622031649520077,1.7510149601511857,0.7104660844148053,0.9884770959627627,-0.01249402587824863,1.1791016511727834,0.10309040916855126,0.010907357520276812,-0.036040615240763116,0.42981160276593183,-0.4338439486214293,1.0239295819857912,2.284966007398189,-0.2798379365454374,-0.8473098246926763,-0.8473098246926763,1.454160780076086,-0.9353499504290953,-0.8473098246926763,-0.036040615240763116,1.1959167885724808,-1.2432072777509597,3.5310561932023865,0.057280464510361444,-1.2752831992039835,-1.4730323578408806,-0.156005530653432,1.576150205122679,-0.594129530873194,-0.01249402587824863,0.057280464510361444,-0.2547520329568809,1.591085893413555,-1.179782889725206,-0.6490285776513719,-0.13170970617137487,0.8798988183330019,0.057280464510361444,0.2152252789325902,-0.7046914435829653,0.28092127296462205,0.6127239700105706,0.17077418478294684,-3.920955863097363,0.4089078305742396,0.2152252789325902,2.1753353551955863,1.7792630156946656,1.7225172205843342,-0.18045600562004682,-0.6490285776513719,0.8055968854608062,-0.059733927382445505,0.10309040916855126,0.8243199236689244,1.093761710301451,-0.9651232031602808,-0.38183149261829497,-0.6214846781566223,-0.156005530653432,-1.2752831992039835,0.9526587487920226,-0.8473098246926763,1.6207544213461318,0.8429440113127525,1.0239295819857912,-0.9353499504290953,-1.4060856588926407,-0.594129530873194,2.0358345353142644,-0.6214846781566223,2.1629094522490995,0.592851555040084,2.448024958691733,0.8982312526302684,-0.2547520329568809,-0.7046914435829653,0.0802551137654914,-0.38183149261829497,1.4072308970681886,0.42981160276593183,0.592851555040084,1.6647577230420412,-0.2298275615859757,0.6521418328596066,2.8203929615640173,1.076435891103936,-0.5669609774156144,0.7296973686019401,-0.5669609774156144,0.6911303718588904,-0.6490285776513719,0.34547107923826165,-0.156005530653432,0.45059639260802203,1.5460733812057033 | 3,477 |
Cytochrome complex | 9 | 16 | 2.726826 | 0.006395 | Q9UDW1,P14406,P13073,P22695,P20674,P00403,O14949,O14548,P14927 | Localization | GO Cellular component | msigdb_gocc | 66,2,228,481,774,619,120,248,287 | 791,248,120,619,1173,1298,228,2,1817,287,1128,774,481,1580,66,1863 | 0.45059639260802203,1.4229478246834266,2.1629094522490995,0.6716892768089571,0.17077418478294684,0.10309040916855126,1.5004365612200485,4.053723242400452,-0.156005530653432,1.3113456984812744,0.1930659788602032,0.4712633310682175,0.8798988183330019,-0.036040615240763116,2.677067202689612,-0.156005530653432 | 3,477 |
Scotoma | 6 | 14 | 2.715815 | 0.006611 | P00846,O60313,Q9H061,P03886,Q9Y5Y0,Q9H6K4 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 8,234,56,218,220,152 | 528,1293,234,238,1250,8,218,2442,953,2978,3108,56,152,220 | 0.8055968854608062,0.10309040916855126,1.4850830339872365,1.454160780076086,0.12578776192278873,3.8776383909815935,1.5460733812057033,-0.46011072625306215,0.32407975809190903,-0.7896574082543483,-0.9057916890941692,2.7801609678496,1.916883074110937,1.5460733812057033 | 3,477 |
Protein import | 22 | 85 | 2.707773 | 0.006774 | O60830,Q99595,O14737,Q9NS69,Q99623,O43615,Q96P70,O15397,Q15388,O95373,Q9UKG1,O96008,O95831,P56589,P40855,Q9Y512,O14925,Q8N1F7,P52292,Q7Z4Q2,O75381,Q92973 | Processes and pathways | GO Biological process | msigdb_gobp | 0,1,370,6,393,386,546,537,422,178,187,455,454,211,464,223,101,487,237,493,365,254 | 1291,2815,2855,370,101,537,386,0,1570,365,1375,745,1377,178,1296,454,455,1378,2281,2129,1874,1875,1929,2237,1930,2820,3300,2650,1528,2980,1436,1031,2656,464,2242,1219,237,2550,1388,1132,211,985,3303,2553,2874,1306,3145,1588,1733,2708,1035,2414,721,422,3043,1792,1489,552,2207,1106,1351,493,487,1235,1149,254,546,1606,834,1,393,1655,2264,3002,886,1210,6,2531,2677,3401,187,1369,1425,223,1084 | 0.10309040916855126,-0.67676342294761,-0.7046914435829653,1.093761710301451,2.3206535481076274,0.7867740121764749,1.076435891103936,4.729861486365382,-0.036040615240763116,1.1110006232313312,0.057280464510361444,0.49181353408407796,0.057280464510361444,1.7510149601511857,0.10309040916855126,0.9526587487920226,0.9526587487920226,0.057280464510361444,-0.38183149261829497,-0.3050870328676839,-0.18045600562004682,-0.18045600562004682,-0.20506278845667675,-0.35608198164205196,-0.20506278845667675,-0.67676342294761,-1.2432072777509597,-0.5669609774156144,-0.01249402587824863,-0.7896574082543483,0.034165029853640824,0.25915163831136523,-0.5669609774156144,0.9346103914962526,-0.35608198164205196,0.1483485632559681,1.4696579604993205,-0.5131751901331499,0.057280464510361444,0.1930659788602032,1.576150205122679,0.3025635649487059,-1.2432072777509597,-0.5131751901331499,-0.7046914435829653,0.10309040916855126,-0.9651232031602808,-0.036040615240763116,-0.10756689934795993,-0.594129530873194,0.25915163831136523,-0.4338439486214293,0.5325681239141068,1.0062486792449554,-0.8473098246926763,-0.13170970617137487,0.010907357520276812,0.7678504081670597,-0.33050110950497374,0.2152252789325902,0.0802551137654914,0.8614700219449289,0.8798988183330019,0.1483485632559681,0.1930659788602032,1.4072308970681886,0.7867740121764749,-0.036040615240763116,0.42981160276593183,4.593322988469487,1.076435891103936,-0.059733927382445505,-0.35608198164205196,-0.7896574082543483,0.3878839297734311,0.17077418478294684,4.015650297766216,-0.48655380913412877,-0.5669609774156144,-1.6101555780664825,1.708173559202872,0.0802551137654914,0.057280464510361444,1.5309311892284372,0.23725339987245142 | 3,477 |
Establishment of protein localization to organelle | 59 | 190 | 2.706914 | 0.006791 | O60830,Q99595,O14737,Q9NS69,Q99623,Q15005,Q15070,O43615,O00165,P61009,Q9H444,Q96RL7,Q96P70,Q9H1Z9,Q9Y5M8,O43464,O15397,Q9H270,Q8N4H5,Q15388,Q99523,Q3ZCQ8,Q15629,P55786,P52789,O95373,P11279,Q9H9H4,Q9UKG1,Q9UGP8,Q14108,Q9Y3D6,O96008,O95831,P51572,P46379,Q9Y230,P30536,P56589,Q14978,P40855,Q8WWC4,Q9Y5L4,Q6UWE0,Q9Y512,P61026,Q10713,O14925,Q8N1F7,Q99797,Q99442,P0DP25,P52292,P46934,Q7Z4Q2,O75381,Q07812,Q5JRX3,Q92973 | Processes and pathways | GO Biological process | msigdb_gobp | 0,1,370,6,393,647,10,386,506,515,673,408,546,31,159,539,537,424,38,422,554,552,40,297,420,178,676,704,187,716,71,335,455,454,582,204,728,210,211,721,464,476,480,475,223,735,600,101,487,630,629,106,237,482,493,365,517,638,254 | 506,2534,1427,2180,1291,2815,2855,2816,370,101,925,537,539,386,926,1214,0,2388,1570,2026,365,1169,1375,2936,745,1377,1250,178,2390,1524,1296,454,455,1378,2281,2129,1874,1875,1928,2861,106,1929,2237,1256,676,1930,2820,3120,2333,3069,1579,3300,2650,2785,210,2902,1528,2980,1436,2544,1031,3097,2656,464,204,482,2944,1261,2945,1882,2242,1219,2703,2657,2985,2140,582,237,2550,420,1388,1132,297,211,985,2453,515,2090,735,849,3303,2553,2874,3039,2093,1306,517,3145,600,1588,1733,2708,1035,71,2299,2414,721,647,10,422,40,3043,1792,2252,1489,552,1102,638,2207,1989,475,3168,1106,2995,1351,493,2913,2160,487,1201,38,3339,1235,1149,476,254,1845,546,1606,408,629,1413,554,834,2369,1,393,630,1364,1608,1280,1655,2264,764,31,424,2111,3000,673,3002,704,886,1210,6,2531,1243,998,2889,2173,2430,2478,716,999,2677,3401,889,187,1369,1425,3154,1165,728,1863,1811,1669,335,223,1084,480,159 | 0.8243199236689244,-0.5131751901331499,0.034165029853640824,-0.33050110950497374,0.10309040916855126,-0.67676342294761,-0.7046914435829653,-0.67676342294761,1.093761710301451,2.3206535481076274,0.34547107923826165,0.7867740121764749,0.7867740121764749,1.076435891103936,0.34547107923826165,0.1483485632559681,4.729861486365382,-0.4338439486214293,-0.036040615240763116,-0.2547520329568809,1.1110006232313312,0.17077418478294684,0.057280464510361444,-0.7611361133509404,0.49181353408407796,0.057280464510361444,0.12578776192278873,1.7510149601511857,-0.4338439486214293,-0.01249402587824863,0.10309040916855126,0.9526587487920226,0.9526587487920226,0.057280464510361444,-0.38183149261829497,-0.3050870328676839,-0.18045600562004682,-0.18045600562004682,-0.20506278845667675,-0.7046914435829653,2.284966007398189,-0.20506278845667675,-0.35608198164205196,0.12578776192278873,0.592851555040084,-0.20506278845667675,-0.67676342294761,-0.9353499504290953,-0.4077515144924765,-0.8764458292816217,-0.036040615240763116,-1.2432072777509597,-0.5669609774156144,-0.6490285776513719,1.576150205122679,-0.7328149058045688,-0.01249402587824863,-0.7896574082543483,0.034165029853640824,-0.5131751901331499,0.25915163831136523,-0.9057916890941692,-0.5669609774156144,0.9346103914962526,1.591085893413555,0.8798988183330019,-0.7611361133509404,0.12578776192278873,-0.7611361133509404,-0.18045600562004682,-0.35608198164205196,0.1483485632559681,-0.594129530873194,-0.5669609774156144,-0.7896574082543483,-0.3050870328676839,0.7104660844148053,1.4696579604993205,-0.5131751901331499,1.0062486792449554,0.057280464510361444,0.1930659788602032,1.278766009486297,1.576150205122679,0.3025635649487059,-0.46011072625306215,0.8243199236689244,-0.2798379365454374,0.5122481028192044,0.4089078305742396,-1.2432072777509597,-0.5131751901331499,-0.7046914435829653,-0.8473098246926763,-0.2798379365454374,0.10309040916855126,0.8243199236689244,-0.9651232031602808,0.6911303718588904,-0.036040615240763116,-0.10756689934795993,-0.594129530873194,0.25915163831136523,2.6134173692391474,-0.38183149261829497,-0.4338439486214293,0.5325681239141068,0.6324870611210252,3.7388244635191787,1.0062486792449554,3.050568026938457,-0.8473098246926763,-0.13170970617137487,-0.35608198164205196,0.010907357520276812,0.7678504081670597,0.2152252789325902,0.6521418328596066,-0.33050110950497374,-0.2298275615859757,0.8982312526302684,-0.9951140817015471,0.2152252789325902,-0.7896574082543483,0.0802551137654914,0.8614700219449289,-0.7328149058045688,-0.3050870328676839,0.8798988183330019,0.17077418478294684,3.1589648600159195,-1.3401781938177342,0.1483485632559681,0.1930659788602032,0.8982312526302684,1.4072308970681886,-0.156005530653432,0.7867740121764749,-0.036040615240763116,1.0415205771938503,0.6716892768089571,0.057280464510361444,0.7678504081670597,0.42981160276593183,-0.4077515144924765,4.593322988469487,1.076435891103936,0.6716892768089571,0.0802551137654914,-0.036040615240763116,0.12578776192278873,-0.059733927382445505,-0.35608198164205196,0.49181353408407796,3.288747263461843,1.0062486792449554,-0.2798379365454374,-0.7896574082543483,0.6127239700105706,-0.7896574082543483,0.5728687985988167,0.3878839297734311,0.17077418478294684,4.015650297766216,-0.48655380913412877,0.1483485632559681,0.3025635649487059,-0.7046914435829653,-0.3050870328676839,-0.4338439486214293,-0.46011072625306215,0.5527746697318787,0.3025635649487059,-0.5669609774156144,-1.6101555780664825,0.3878839297734311,1.708173559202872,0.0802551137654914,0.057280464510361444,-0.9651232031602808,0.1930659788602032,0.5325681239141068,-0.156005530653432,-0.13170970617137487,-0.059733927382445505,1.1959167885724808,1.5309311892284372,0.23725339987245142,0.8982312526302684,1.8762169185952062 | 3,477 |
Nucleotide transmembrane transporter activity | 9 | 14 | 2.702473 | 0.006883 | O00400,P41440,Q9HC21,P12235,Q9BSK2,Q9H2D1,P12236,Q6NUK1,Q8TB61 | Functions | GO Molecular function | msigdb_gomf | 160,224,425,295,327,82,276,440,95 | 160,771,1123,511,295,276,224,440,3082,95,855,327,82,425 | 1.8625451660048729,0.4712633310682175,0.1930659788602032,0.8243199236689244,1.278766009486297,1.34361310413227,1.5157190967783831,0.9706140497703232,-0.8764458292816217,2.4023277992997625,0.4089078305742396,1.2126492640347504,2.51528988241545,1.0062486792449554 | 3,477 |
Regulation of mrna splicing via spliceosome | 34 | 64 | 4.529935 | 0.000006 | P62995,Q8IY67,Q9Y2W1,O75494,P49756,O00422,Q13247,P52756,Q13573,P22626,P19338,P98175,Q14011,Q01130,P18583,Q15007,P98179,P38159,O75525,Q96PU8,P51114,Q13242,Q06787,Q15637,Q07666,Q96T37,Q8WXF0,Q96E39,Q15427,Q08170,Q13595,Q07021,P51116,Q96MU7 | Processes and pathways | GO Biological process | msigdb_gobp | 247,399,407,387,511,386,513,276,280,413,171,295,56,437,686,464,72,74,201,751,209,462,589,596,590,359,96,357,595,378,486,376,375,522 | 386,387,201,2208,936,2211,3028,1775,686,171,413,1779,1226,2656,74,511,209,375,276,1285,1436,247,2232,1649,295,72,3091,437,589,376,590,378,1398,1133,462,513,280,486,56,1041,464,595,596,1187,1345,1503,3121,399,3278,96,747,357,1149,522,751,2551,359,2087,1517,1156,1753,1371,407,2365 | 1.0192729716930538,1.0192729716930538,1.4341117147858753,-0.32339579074041863,0.4692696641062204,-0.32339579074041863,-0.9662858408639224,-0.05691626960112453,0.6644077422188699,1.5608137029341247,0.9871621278015353,-0.05691626960112453,0.27296683220001094,-0.6260946606959044,2.3123708840455612,0.8584229744726526,1.402368545245139,1.0513545753283584,1.2432393107605846,0.24013334861470298,0.14142916094516933,1.3069742818074888,-0.32339579074041863,0.009339846996152005,1.2113297287229814,2.343379067489768,-1.0348382379290142,0.9550218762313673,0.7615532030666726,1.0513545753283584,0.7615532030666726,1.0513545753283584,0.1743647331482899,0.33853323249162104,0.922852047787671,0.8584229744726526,1.2432393107605846,0.89065247147567,2.559784134405456,0.4039669561578337,0.922852047787671,0.7615532030666726,0.7615532030666726,0.3057667222448112,0.2072660552143123,0.10845911446660461,-1.0691809388636886,1.0192729716930538,-1.3803273911864882,2.0634452922827657,0.631963801638392,1.0834071043843578,0.33853323249162104,0.8584229744726526,0.631963801638392,-0.524841194797217,1.0834071043843578,-0.22318875028858487,0.10845911446660461,0.33853323249162104,-0.023770392974690285,0.2072660552143123,1.0192729716930538,-0.3903896488181674 | 3,475 |
mRNA splicing factor | 30 | 67 | 4.1003 | 0.000041 | P62995,Q8IY67,O95391,O75494,Q13247,P09012,P23246,P19338,Q8IWZ8,Q14011,Q15459,Q01130,O60508,P98179,P35637,Q92804,P38159,O75525,Q07955,Q13242,Q15637,O43395,Q8WXF0,Q96E39,Q96PK6,P33240,Q08170,P08579,P62310,Q13595 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 247,399,506,387,513,147,414,171,572,56,439,437,189,72,191,472,74,201,210,462,596,584,96,357,107,482,378,226,484,486 | 1632,584,1873,1028,189,387,201,842,1268,2045,506,226,2208,147,937,171,414,482,191,74,1394,484,2902,1544,3224,247,1649,72,437,2773,590,210,378,1398,1133,1496,462,1084,513,486,56,2979,776,2396,2347,439,596,1187,2540,1656,572,856,399,1147,96,745,472,357,107,751,1517,1575,2359,922,3299,1211,3372 | 0.009339846996152005,0.7615532030666726,-0.12331590050833183,0.4039669561578337,1.4658276708247233,1.0192729716930538,1.4341117147858753,0.5344429793834905,0.24013334861470298,-0.22318875028858487,0.8584229744726526,1.338799977605599,-0.32339579074041863,1.7185927649678452,0.4692696641062204,1.5608137029341247,0.9871621278015353,0.89065247147567,1.4658276708247233,2.3123708840455612,0.1743647331482899,0.89065247147567,-0.8297032421061233,0.07545436686033442,-1.2415741430250644,1.3069742818074888,0.009339846996152005,2.343379067489768,0.9550218762313673,-0.72771255680608,0.7615532030666726,1.402368545245139,1.0513545753283584,0.1743647331482899,0.33853323249162104,0.10845911446660461,0.922852047787671,0.3712665741938593,0.8584229744726526,0.89065247147567,2.559784134405456,-0.8979084274692133,0.5994884884196273,-0.42394413865700914,-0.3903896488181674,0.9550218762313673,0.7615532030666726,0.3057667222448112,-0.524841194797217,0.009339846996152005,0.7938735177908782,0.5344429793834905,1.0192729716930538,0.33853323249162104,2.0634452922827657,0.631963801638392,0.922852047787671,1.0834071043843578,2.0009706871850725,0.631963801638392,0.10845911446660461,0.07545436686033442,-0.3903896488181674,0.5018723958328761,-1.4151355272862594,0.3057667222448112,-1.6953932674425685 | 3,475 |
Protein localization | 43 | 75 | 4.026683 | 0.000057 | O15228,P09110,O60830,Q9Y2Q3,Q99595,Q9UJS0,O75521,O96011,O95169,P34913,O43615,P09601,Q13190,P50402,P05067,Q5T8D3,O43808,Q9BY49,P46379,P10809,Q9NS69,P56589,O15254,P06576,Q9HAV7,O75746,Q9Y3D6,O75381,Q15067,O96008,P51553,O75874,Q9Y276,P22307,Q9NX63,Q5JRX3,Q08426,O00116,O14734,P21796,Q9NR77,Q9Y512,Q8N4H5 | Processes and pathways | Reactome Pathways | msigdb_reactome | 365,246,3,925,134,677,388,886,16,23,273,646,894,893,274,658,534,167,537,536,39,41,169,292,576,806,52,430,315,932,692,75,877,847,121,105,852,346,477,110,118,259,784 | 346,477,1426,365,169,273,2792,1827,534,3,430,3050,1217,1636,388,806,75,1381,16,932,886,274,292,1771,246,646,536,1477,1988,2467,110,847,1078,1642,23,1180,1120,1482,940,537,893,692,2173,1489,41,1124,852,1001,3464,894,1551,315,1239,1294,105,658,3069,2299,784,2078,2987,134,2189,167,576,118,39,121,1627,677,877,925,52,259,2456 | 1.0834071043843578,0.89065247147567,0.14142916094516933,1.0513545753283584,1.5608137029341247,1.2432393107605846,-0.761667607945778,-0.09009802404997375,0.8261633820993779,4.902800840805222,0.9550218762313673,-1.0005399910393864,0.27296683220001094,0.009339846996152005,1.0192729716930538,0.5669816119272515,2.281339075443853,0.1743647331482899,3.655839397007132,0.4692696641062204,0.5018723958328761,1.2432393107605846,1.2113297287229814,-0.05691626960112453,1.3069742818074888,0.6968204986884444,0.8261633820993779,0.10845911446660461,-0.18986101163713162,-0.4911696283708453,1.9696962435077099,0.5344429793834905,0.3712665741938593,0.009339846996152005,3.1720572250461965,0.3057667222448112,0.33853323249162104,0.10845911446660461,0.4692696641062204,0.8261633820993779,0.5018723958328761,0.6644077422188699,-0.2899558780062751,0.10845911446660461,2.775073997044326,0.33853323249162104,0.5344429793834905,0.4366345847838189,-3.6871244846496367,0.5018723958328761,0.07545436686033442,1.1793918752131152,0.27296683220001094,0.24013334861470298,2.0009706871850725,0.6968204986884444,-1.0005399910393864,-0.3568736241903287,0.5994884884196273,-0.22318875028858487,-0.8979084274692133,1.8129476360755272,-0.2899558780062751,1.5924222429530126,0.7938735177908782,1.93839687467804,2.8670084338016997,1.9070724559775802,0.04241468851205189,0.6968204986884444,0.5344429793834905,0.5018723958328761,2.590607268495023,1.3069742818074888,-0.4575373713799266 | 3,475 |
Regulation of rna splicing | 44 | 89 | 4.020038 | 0.000058 | P62995,Q8IY67,Q9Y2W1,Q8IXT5,O75494,P49756,Q13247,P55795,O00422,P31942,Q14320,P52756,Q13573,P22626,P19338,P98175,Q14011,P18583,Q01130,P98179,P35637,Q15007,P38159,O75525,Q96PU8,Q07955,P51114,Q13242,Q06787,Q15637,P49761,Q07666,Q96T37,Q8WXF0,Q96E39,Q15427,Q08170,Q9NYV4,P51116,Q07021,Q13595,Q96MU7,Q09666,Q12849 | Processes and pathways | GO Biological process | msigdb_gobp | 247,399,407,660,387,511,513,649,386,391,394,276,280,413,171,295,56,686,437,72,191,464,74,201,751,210,209,462,589,596,208,590,359,96,357,595,378,384,375,376,486,522,248,249 | 386,768,2576,387,201,2208,936,2211,3028,1775,686,171,413,1778,1779,1226,2656,391,889,191,74,2282,511,208,209,375,947,276,1285,649,1436,2062,247,2232,1649,295,72,3091,437,1437,589,376,590,210,378,1398,248,249,1133,462,1084,513,280,486,56,394,1041,1603,464,595,596,1187,1345,1503,1605,3121,660,399,3278,2248,96,747,357,1149,522,751,2551,359,2087,1517,1156,2757,1747,384,1753,1259,1371,407,2365 | 1.0192729716930538,0.5994884884196273,-0.5585523596845848,1.0192729716930538,1.4341117147858753,-0.32339579074041863,0.4692696641062204,-0.32339579074041863,-0.9662858408639224,-0.05691626960112453,0.6644077422188699,1.5608137029341247,0.9871621278015353,-0.05691626960112453,-0.05691626960112453,0.27296683220001094,-0.6260946606959044,1.0192729716930538,0.5018723958328761,1.4658276708247233,2.3123708840455612,-0.3568736241903287,0.8584229744726526,1.402368545245139,1.402368545245139,1.0513545753283584,0.4692696641062204,1.2432393107605846,0.24013334861470298,0.6968204986884444,0.14142916094516933,-0.22318875028858487,1.3069742818074888,-0.32339579074041863,0.009339846996152005,1.2113297287229814,2.343379067489768,-1.0348382379290142,0.9550218762313673,0.14142916094516933,0.7615532030666726,1.0513545753283584,0.7615532030666726,1.402368545245139,1.0513545753283584,0.1743647331482899,1.3069742818074888,1.3069742818074888,0.33853323249162104,0.922852047787671,0.3712665741938593,0.8584229744726526,1.2432393107605846,0.89065247147567,2.559784134405456,1.0192729716930538,0.4039669561578337,0.04241468851205189,0.922852047787671,0.7615532030666726,0.7615532030666726,0.3057667222448112,0.2072660552143123,0.10845911446660461,0.04241468851205189,-1.0691809388636886,0.6968204986884444,1.0192729716930538,-1.3803273911864882,-0.32339579074041863,2.0634452922827657,0.631963801638392,1.0834071043843578,0.33853323249162104,0.8584229744726526,0.631963801638392,-0.524841194797217,1.0834071043843578,-0.22318875028858487,0.10845911446660461,0.33853323249162104,-0.6937989237284957,-0.023770392974690285,1.0513545753283584,-0.023770392974690285,0.27296683220001094,0.2072660552143123,1.0192729716930538,-0.3903896488181674 | 3,475 |
Mitochondrial transmembrane transport | 19 | 50 | 3.835812 | 0.000125 | O43772,O60830,Q99595,Q9Y4W6,O43615,P10809,P06576,Q8IYU8,P56385,Q9Y619,P36542,Q9UJZ1,Q96NB2,Q9BPX6,O75947,P48047,P21796,O95831,P50416 | Processes and pathways | GO Biological process | msigdb_gobp | 1,3,134,553,273,536,292,179,183,187,456,364,495,240,348,229,110,109,113 | 1426,273,1,3,1266,1636,806,348,3234,1381,1327,1876,109,932,3264,1428,292,536,1477,1988,110,1329,688,1078,456,229,113,1946,1543,183,1714,1239,1444,1294,1138,179,1007,1354,1197,495,134,240,970,3196,1418,576,677,364,553,187 | 0.14142916094516933,1.2432393107605846,5.514987445868287,4.902800840805222,0.24013334861470298,0.009339846996152005,0.5669816119272515,1.0834071043843578,-1.2761913810585277,0.1743647331482899,0.2072660552143123,-0.12331590050833183,1.9696962435077099,0.4692696641062204,-1.3455675981762987,0.14142916094516933,1.2113297287229814,0.8261633820993779,0.10845911446660461,-0.18986101163713162,1.9696962435077099,0.2072660552143123,0.6644077422188699,0.3712665741938593,0.922852047787671,1.338799977605599,1.93839687467804,-0.15657014623897816,0.07545436686033442,1.4975165585697592,-0.023770392974690285,0.27296683220001094,0.14142916094516933,0.24013334861470298,0.33853323249162104,1.5291785218097205,0.4366345847838189,0.2072660552143123,0.3057667222448112,0.89065247147567,1.8129476360755272,1.338799977605599,0.4692696641062204,-1.1724794204274362,0.1743647331482899,0.7938735177908782,0.6968204986884444,1.0834071043843578,0.8261633820993779,1.4975165585697592 | 3,475 |
Mitochondrial translation | 36 | 63 | 3.8338 | 0.000126 | Q9BYD1,Q9Y2R9,Q9BYD6,Q9H2W6,O75616,Q14197,Q96EY7,Q13405,P82930,P82673,Q96RP9,Q8IXM3,Q13084,P82663,Q92665,Q9NQ50,O75394,Q9Y3D9,Q9NX20,P82912,Q96A35,Q9HD33,Q9Y3B7,Q16540,Q92552,P52815,P82650,Q9BYD2,Q9BYC9,Q9BZE1,Q9BYD3,P82664,P09001,P82933,Q8TAE8,P49411 | Processes and pathways | Reactome Pathways | msigdb_reactome | 1056,532,267,1057,883,774,545,416,651,538,830,42,296,294,574,61,930,475,474,694,329,870,345,82,746,87,588,758,361,1016,242,850,723,727,115,997 | 930,883,723,1890,2223,997,1710,87,588,294,850,538,1546,694,1231,651,727,296,416,774,2010,82,1090,2018,2492,3277,42,2352,1732,115,746,574,329,2550,1248,545,1150,830,1810,361,1056,758,242,267,1016,1057,1968,870,1625,61,2994,1861,474,1679,1061,1867,1162,532,2516,345,2454,475,1213 | 0.4692696641062204,0.5018723958328761,0.631963801638392,-0.12331590050833183,-0.32339579074041863,0.4366345847838189,-0.023770392974690285,2.1258216652317476,0.7615532030666726,1.2113297287229814,0.5344429793834905,0.8261633820993779,0.07545436686033442,0.6644077422188699,0.27296683220001094,0.6968204986884444,0.631963801638392,1.2113297287229814,0.9871621278015353,0.5994884884196273,-0.18986101163713162,2.2502835286953093,0.3712665741938593,-0.18986101163713162,-0.4911696283708453,-1.3803273911864882,2.775073997044326,-0.3903896488181674,-0.023770392974690285,1.93839687467804,0.631963801638392,0.7938735177908782,1.1474255928962198,-0.524841194797217,0.27296683220001094,0.8261633820993779,0.33853323249162104,0.5669816119272515,-0.05691626960112453,1.0834071043843578,0.4039669561578337,0.631963801638392,1.338799977605599,1.275120777065889,0.4366345847838189,0.4039669561578337,-0.15657014623897816,0.5344429793834905,0.04241468851205189,2.4671777752406974,-0.8979084274692133,-0.09009802404997375,0.922852047787671,0.009339846996152005,0.4039669561578337,-0.09009802404997375,0.33853323249162104,0.8584229744726526,-0.4911696283708453,1.1154307228188172,-0.4575373713799266,0.922852047787671,0.3057667222448112 | 3,475 |
Regulation of mrna processing | 39 | 88 | 3.753461 | 0.000174 | P62995,Q8IY67,Q9Y2W1,O75494,P49756,Q13247,O00422,P09012,Q5VTR2,P52756,Q13573,P22626,P19338,P98175,P18615,Q96ST2,Q14011,Q01130,P98179,Q15007,Q6P1J9,P38159,O75525,Q6PJT7,P51114,Q13242,Q06787,Q15637,Q8N7H5,Q07666,Q8WXF0,Q96T37,Q96E39,Q14151,Q08170,P51116,Q07021,Q13595,Q96MU7 | Processes and pathways | GO Biological process | msigdb_gobp | 247,399,407,387,511,513,386,147,418,276,280,413,171,295,45,446,56,437,72,464,600,74,201,467,209,462,589,596,219,590,96,359,357,487,378,375,376,486,522 | 1110,386,1028,3107,1168,387,201,2208,147,936,2211,3028,1775,686,45,171,413,1779,1226,2656,74,511,1227,2661,209,375,2117,276,1285,1436,247,2232,1649,295,72,3091,437,589,376,590,378,1234,1398,1133,462,513,280,486,56,487,1041,464,734,595,596,1187,899,1345,1503,418,780,600,903,467,1190,3121,399,3278,1143,219,96,747,357,1149,522,751,2551,446,359,2087,1517,2311,1156,1366,1753,1371,407,2365 | 0.33853323249162104,1.0192729716930538,0.4039669561578337,-1.0691809388636886,0.3057667222448112,1.0192729716930538,1.4341117147858753,-0.32339579074041863,1.7185927649678452,0.4692696641062204,-0.32339579074041863,-0.9662858408639224,-0.05691626960112453,0.6644077422188699,2.7443852320603073,1.5608137029341247,0.9871621278015353,-0.05691626960112453,0.27296683220001094,-0.6260946606959044,2.3123708840455612,0.8584229744726526,0.27296683220001094,-0.6260946606959044,1.402368545245139,1.0513545753283584,-0.25655361902926604,1.2432393107605846,0.24013334861470298,0.14142916094516933,1.3069742818074888,-0.32339579074041863,0.009339846996152005,1.2113297287229814,2.343379067489768,-1.0348382379290142,0.9550218762313673,0.7615532030666726,1.0513545753283584,0.7615532030666726,1.0513545753283584,0.27296683220001094,0.1743647331482899,0.33853323249162104,0.922852047787671,0.8584229744726526,1.2432393107605846,0.89065247147567,2.559784134405456,0.89065247147567,0.4039669561578337,0.922852047787671,0.631963801638392,0.7615532030666726,0.7615532030666726,0.3057667222448112,0.5018723958328761,0.2072660552143123,0.10845911446660461,0.9871621278015353,0.5994884884196273,0.7615532030666726,0.5018723958328761,0.922852047787671,0.3057667222448112,-1.0691809388636886,1.0192729716930538,-1.3803273911864882,0.33853323249162104,1.3705980155545952,2.0634452922827657,0.631963801638392,1.0834071043843578,0.33853323249162104,0.8584229744726526,0.631963801638392,-0.524841194797217,0.9550218762313673,1.0834071043843578,-0.22318875028858487,0.10845911446660461,-0.3568736241903287,0.33853323249162104,0.2072660552143123,-0.023770392974690285,0.2072660552143123,1.0192729716930538,-0.3903896488181674 | 3,475 |
Regulation of alternative mrna splicing via spliceosome | 18 | 29 | 3.712496 | 0.000205 | Q96T37,P62995,Q8WXF0,Q8IY67,Q01130,Q15007,Q9Y2W1,P38159,P98175,O75525,P51114,P49756,O00422,Q13247,P51116,Q06787,Q96MU7,P52756 | Processes and pathways | GO Biological process | msigdb_gobp | 359,247,96,399,437,464,407,74,295,201,209,511,386,513,375,589,522,276 | 386,201,936,3028,1775,1226,74,511,209,375,276,247,295,3091,437,589,590,513,464,1345,399,96,747,522,359,1517,1753,407,2365 | 1.0192729716930538,1.4341117147858753,0.4692696641062204,-0.9662858408639224,-0.05691626960112453,0.27296683220001094,2.3123708840455612,0.8584229744726526,1.402368545245139,1.0513545753283584,1.2432393107605846,1.3069742818074888,1.2113297287229814,-1.0348382379290142,0.9550218762313673,0.7615532030666726,0.7615532030666726,0.8584229744726526,0.922852047787671,0.2072660552143123,1.0192729716930538,2.0634452922827657,0.631963801638392,0.8584229744726526,1.0834071043843578,0.10845911446660461,-0.023770392974690285,1.0192729716930538,-0.3903896488181674 | 3,475 |
Signaling | 11 | 20 | 3.642947 | 0.00027 | Q8WUJ1,O15173,P51858,Q96PC5,Q07820,Q7Z4V5,Q9Y3E1,O00264,P43490,O75475,Q99627 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 4,38,9,206,377,175,53,337,28,123,360 | 337,1691,38,123,1277,1836,28,9,591,377,460,822,175,1565,4,1303,206,360,3231,53 | 1.1154307228188172,-0.023770392974690285,2.8670084338016997,1.8757228615346935,0.24013334861470298,-0.09009802404997375,3.1112169427024057,3.9257537181006645,0.7615532030666726,1.0513545753283584,0.922852047787671,0.5669816119272515,1.5608137029341247,0.07545436686033442,4.814759722518884,0.24013334861470298,1.4341117147858753,1.0834071043843578,-1.2415741430250644,2.590607268495023 | 3,475 |
Negative regulation of mrna processing | 12 | 23 | 3.519105 | 0.000433 | Q8WXF0,P22626,P38159,P98175,P18615,Q6PJT7,O75494,Q08170,Q13242,O00422,Q07021,Q5VTR2 | Processes and pathways | GO Biological process | msigdb_gobp | 96,413,74,295,45,467,387,378,462,386,376,418 | 1110,386,1168,387,45,413,1779,1226,74,1227,1436,295,376,378,1133,462,513,1187,418,903,467,96,2087 | 0.33853323249162104,1.0192729716930538,0.3057667222448112,1.0192729716930538,2.7443852320603073,0.9871621278015353,-0.05691626960112453,0.27296683220001094,2.3123708840455612,0.27296683220001094,0.14142916094516933,1.2113297287229814,1.0513545753283584,1.0513545753283584,0.33853323249162104,0.922852047787671,0.8584229744726526,0.3057667222448112,0.9871621278015353,0.5018723958328761,0.922852047787671,2.0634452922827657,-0.22318875028858487 | 3,475 |
Alternative mrna splicing via spliceosome | 24 | 41 | 3.501268 | 0.000463 | P62995,Q8IY67,Q9Y2W1,O95391,P49756,O00422,Q13247,P52756,P23246,Q96I25,P98175,Q01130,Q15007,P38159,O75525,P51114,Q07955,Q13242,Q06787,Q07666,Q96T37,Q8WXF0,P51116,Q96MU7 | Processes and pathways | GO Biological process | msigdb_gobp | 247,399,407,506,511,386,513,276,414,708,295,437,464,74,201,209,210,462,589,590,359,96,375,522 | 386,1828,768,201,506,936,3028,1775,414,1226,74,511,209,375,946,276,247,295,3091,437,589,590,210,1234,1133,462,513,1402,464,1345,399,96,747,708,522,359,1517,1753,407,3249,2365 | 1.0192729716930538,-0.09009802404997375,0.5994884884196273,1.4341117147858753,0.8584229744726526,0.4692696641062204,-0.9662858408639224,-0.05691626960112453,0.9871621278015353,0.27296683220001094,2.3123708840455612,0.8584229744726526,1.402368545245139,1.0513545753283584,0.4692696641062204,1.2432393107605846,1.3069742818074888,1.2113297287229814,-1.0348382379290142,0.9550218762313673,0.7615532030666726,0.7615532030666726,1.402368545245139,0.27296683220001094,0.33853323249162104,0.922852047787671,0.8584229744726526,0.1743647331482899,0.922852047787671,0.2072660552143123,1.0192729716930538,2.0634452922827657,0.631963801638392,0.6644077422188699,0.8584229744726526,1.0834071043843578,0.10845911446660461,-0.023770392974690285,1.0192729716930538,-1.2761913810585277,-0.3903896488181674 | 3,475 |
Mitochondrial protein import | 9 | 34 | 3.484065 | 0.000494 | Q9NX63,O60830,Q99595,Q9NS69,Q5JRX3,P21796,O95169,Q9Y512,O43615 | Processes and pathways | Reactome Pathways | msigdb_reactome | 121,3,134,39,105,110,16,259,273 | 1426,273,3,3050,1217,1636,806,1381,16,932,292,1771,536,1477,1988,110,1078,1120,692,1001,1551,1239,1294,105,784,134,2189,576,39,121,677,877,259,2456 | 0.14142916094516933,1.2432393107605846,4.902800840805222,-1.0005399910393864,0.27296683220001094,0.009339846996152005,0.5669816119272515,0.1743647331482899,3.655839397007132,0.4692696641062204,1.2113297287229814,-0.05691626960112453,0.8261633820993779,0.10845911446660461,-0.18986101163713162,1.9696962435077099,0.3712665741938593,0.33853323249162104,0.6644077422188699,0.4366345847838189,0.07545436686033442,0.27296683220001094,0.24013334861470298,2.0009706871850725,0.5994884884196273,1.8129476360755272,-0.2899558780062751,0.7938735177908782,2.8670084338016997,1.9070724559775802,0.6968204986884444,0.5344429793834905,1.3069742818074888,-0.4575373713799266 | 3,475 |
Negative regulation of rna splicing | 9 | 18 | 3.310626 | 0.000931 | Q8WXF0,P22626,P38159,P98175,Q08170,O75494,Q13242,O00422,Q07021 | Processes and pathways | GO Biological process | msigdb_gobp | 96,413,74,295,378,387,462,386,376 | 386,387,413,1779,1226,74,1436,2062,295,376,378,1133,462,513,1187,96,2087,1259 | 1.0192729716930538,1.0192729716930538,0.9871621278015353,-0.05691626960112453,0.27296683220001094,2.3123708840455612,0.14142916094516933,-0.22318875028858487,1.2113297287229814,1.0513545753283584,1.0513545753283584,0.33853323249162104,0.922852047787671,0.8584229744726526,0.3057667222448112,2.0634452922827657,-0.22318875028858487,0.27296683220001094 | 3,475 |
Inner mitochondrial membrane protein complex | 39 | 79 | 3.297749 | 0.000975 | O60830,Q99595,Q16891,O43920,O95169,Q9Y4W6,P14927,O43674,Q9HAV7,Q8IYU8,P06576,O00483,P56385,Q99623,P13073,P20674,P24539,O14548,P10606,Q6UXV4,Q9Y375,P36542,Q96IX5,Q9UDW1,Q16795,Q9Y276,P35232,P22695,Q9NVH1,Q9BPX6,Q9Y512,P03886,O75947,O75306,O95168,P48047,Q5XKP0,O43676,Q9NX63 | Localization | GO Cellular component | msigdb_gocc | 3,134,515,504,16,553,40,410,576,179,292,800,183,319,433,687,688,188,809,204,79,456,344,873,597,877,455,586,760,240,259,349,348,347,721,229,736,613,121 | 800,188,1426,2418,410,613,3343,504,3,1634,347,1635,1217,841,348,3234,721,16,885,2372,2159,2421,3264,349,2464,292,1771,809,1988,433,1989,1990,40,1703,938,687,1224,586,688,1078,2470,2423,3114,455,456,1120,229,1487,1838,1543,183,1551,2181,597,515,1294,2348,736,204,3170,179,1007,965,344,134,319,240,3445,576,760,1209,121,2260,873,877,79,553,259,2265 | 0.5669816119272515,1.4658276708247233,0.14142916094516933,-0.4575373713799266,0.9871621278015353,0.7292022575003356,-1.554860075681201,0.8584229744726526,4.902800840805222,0.009339846996152005,1.0834071043843578,0.009339846996152005,0.27296683220001094,0.5344429793834905,1.0834071043843578,-1.2761913810585277,0.631963801638392,3.655839397007132,0.5018723958328761,-0.42394413865700914,-0.2899558780062751,-0.4575373713799266,-1.3455675981762987,1.0834071043843578,-0.4911696283708453,1.2113297287229814,-0.05691626960112453,0.5669816119272515,-0.18986101163713162,0.9550218762313673,-0.18986101163713162,-0.18986101163713162,2.836385499712057,-0.023770392974690285,0.4692696641062204,0.6644077422188699,0.27296683220001094,0.7615532030666726,0.6644077422188699,0.3712665741938593,-0.4911696283708453,-0.4575373713799266,-1.0691809388636886,0.922852047787671,0.922852047787671,0.33853323249162104,1.338799977605599,0.10845911446660461,-0.09009802404997375,0.07545436686033442,1.4975165585697592,0.07545436686033442,-0.2899558780062751,0.7615532030666726,0.8584229744726526,0.24013334861470298,-0.3903896488181674,0.631963801638392,1.4341117147858753,-1.1380011591326509,1.5291785218097205,0.4366345847838189,0.4692696641062204,1.1154307228188172,1.8129476360755272,1.1793918752131152,1.338799977605599,-2.5574276464493524,0.7938735177908782,0.631963801638392,0.3057667222448112,1.9070724559775802,-0.32339579074041863,0.5344429793834905,0.5344429793834905,2.281339075443853,0.8261633820993779,1.3069742818074888,-0.32339579074041863 | 3,475 |
Negative regulation of mrna splicing via spliceosome | 9 | 16 | 3.250636 | 0.001151 | Q8WXF0,P22626,P38159,P98175,Q08170,O75494,Q13242,O00422,Q07021 | Processes and pathways | GO Biological process | msigdb_gobp | 96,413,74,295,378,387,462,386,376 | 386,387,413,1779,1226,74,1436,295,376,378,1133,462,513,1187,96,2087 | 1.0192729716930538,1.0192729716930538,0.9871621278015353,-0.05691626960112453,0.27296683220001094,2.3123708840455612,0.14142916094516933,1.2113297287229814,1.0513545753283584,1.0513545753283584,0.33853323249162104,0.922852047787671,0.8584229744726526,0.3057667222448112,2.0634452922827657,-0.22318875028858487 | 3,475 |
Negative regulation of mrna metabolic process | 20 | 48 | 3.198999 | 0.001379 | Q9Y2W1,O75494,Q13247,O00422,P67809,Q5VTR2,P22626,A2RRP1,P98175,P18615,Q14011,Q13151,P35637,Q92804,P38159,Q6PJT7,Q13242,Q8WXF0,Q08170,Q07021 | Processes and pathways | GO Biological process | msigdb_gobp | 407,387,513,386,393,418,413,408,295,45,56,568,191,472,74,467,462,96,378,376 | 408,1110,386,802,1168,387,1764,1174,1384,45,413,1779,1226,191,74,1227,1436,393,295,3091,589,376,378,1234,1133,1717,568,462,513,56,3211,2975,1002,2909,1187,418,903,467,2400,3121,96,1569,472,1201,2087,2408,1822,407 | 0.9871621278015353,0.33853323249162104,1.0192729716930538,0.5669816119272515,0.3057667222448112,1.0192729716930538,-0.05691626960112453,0.3057667222448112,0.1743647331482899,2.7443852320603073,0.9871621278015353,-0.05691626960112453,0.27296683220001094,1.4658276708247233,2.3123708840455612,0.27296683220001094,0.14142916094516933,1.0192729716930538,1.2113297287229814,-1.0348382379290142,0.7615532030666726,1.0513545753283584,1.0513545753283584,0.27296683220001094,0.33853323249162104,-0.023770392974690285,0.7938735177908782,0.922852047787671,0.8584229744726526,2.559784134405456,-1.2070036199349412,-0.8979084274692133,0.4366345847838189,-0.8297032421061233,0.3057667222448112,0.9871621278015353,0.5018723958328761,0.922852047787671,-0.42394413865700914,-1.0691809388636886,2.0634452922827657,0.07545436686033442,0.922852047787671,0.3057667222448112,-0.22318875028858487,-0.42394413865700914,-0.05691626960112453,1.0192729716930538 | 3,475 |
Organelle fusion | 27 | 51 | 3.17988 | 0.001473 | O95140,Q8NAN2,Q9BSR8,Q9Y3E7,Q9Y4W6,Q9NQG6,Q13190,Q5SQN1,Q12981,Q9H270,O60313,Q9NVJ2,Q9P2R3,Q9Y3D6,Q86Y82,O00161,P07355,P02786,O95721,Q9UNK0,Q8WUH2,O60499,Q9UJZ1,Q15075,Q07812,P51809,Q9NX63 | Processes and pathways | GO Biological process | msigdb_gobp | 244,662,670,679,553,156,894,543,654,303,411,974,975,52,700,555,559,933,308,334,859,454,364,489,591,618,121 | 555,2152,411,2998,454,1697,1074,244,1532,308,933,1701,2160,559,935,1781,2172,2116,618,2000,591,1650,654,894,2861,489,543,2702,700,2183,1657,662,859,1614,2990,670,2448,303,156,974,121,1680,975,364,1823,334,1160,52,679,553,1929 | 0.7938735177908782,-0.2899558780062751,0.9871621278015353,-0.9320754353215098,0.922852047787671,-0.023770392974690285,0.3712665741938593,1.3069742818074888,0.07545436686033442,1.1793918752131152,0.4692696641062204,-0.023770392974690285,-0.2899558780062751,0.7938735177908782,0.4692696641062204,-0.05691626960112453,-0.2899558780062751,-0.25655361902926604,0.7292022575003356,-0.18986101163713162,0.7615532030666726,0.009339846996152005,0.6968204986884444,0.5018723958328761,-0.7956643954387234,0.89065247147567,0.8261633820993779,-0.6599263948599569,0.6644077422188699,-0.2899558780062751,0.009339846996152005,0.6968204986884444,0.5344429793834905,0.04241468851205189,-0.8979084274692133,0.6968204986884444,-0.4575373713799266,1.2113297287229814,1.6555599569329296,0.4692696641062204,1.9070724559775802,0.009339846996152005,0.4692696641062204,1.0834071043843578,-0.05691626960112453,1.1474255928962198,0.33853323249162104,2.590607268495023,0.6968204986884444,0.8261633820993779,-0.12331590050833183 | 3,475 |
Positive regulation of mrna processing | 11 | 22 | 3.162427 | 0.001565 | P62995,Q13573,Q96E39,P98179,Q9Y2W1,Q6P1J9,P38159,P19338,Q13595,Q14011,Q8N7H5 | Processes and pathways | GO Biological process | msigdb_gobp | 247,280,357,72,407,600,74,171,486,56,219 | 1028,2208,2211,171,2656,74,2117,1285,247,72,1398,280,486,56,595,600,219,357,1149,2311,1371,407 | 0.4039669561578337,-0.32339579074041863,-0.32339579074041863,1.5608137029341247,-0.6260946606959044,2.3123708840455612,-0.25655361902926604,0.24013334861470298,1.3069742818074888,2.343379067489768,0.1743647331482899,1.2432393107605846,0.89065247147567,2.559784134405456,0.7615532030666726,0.7615532030666726,1.3705980155545952,1.0834071043843578,0.33853323249162104,-0.3568736241903287,0.2072660552143123,1.0192729716930538 | 3,475 |
Dna damage telomere stress induced senescence | 10 | 19 | 3.159205 | 0.001582 | Q96L91,Q9NYB0,P07305,P16402,P10412,P16104,P16403,P17096,P20700,P62805 | Processes and pathways | Reactome Pathways | msigdb_reactome | 358,402,245,95,190,103,227,141,374,277 | 505,2269,2046,245,190,103,95,227,141,2161,374,3222,1647,277,2288,1555,1097,358,402 | 0.8584229744726526,-0.3568736241903287,-0.22318875028858487,1.3069742818074888,1.4658276708247233,2.0009706871850725,2.0634452922827657,1.338799977605599,1.750070167664919,-0.2899558780062751,1.0513545753283584,-1.2415741430250644,0.009339846996152005,1.2432393107605846,-0.3568736241903287,0.07545436686033442,0.3712665741938593,1.0834071043843578,1.0192729716930538 | 3,475 |
Fad binding | 8 | 11 | 3.116436 | 0.001831 | O15254,Q8NB78,O00116,Q14534,O95831,Q15392,Q15067,Q9Y2Z9 | Functions | GO Molecular function | msigdb_gomf | 169,10,346,327,109,91,315,94 | 346,169,109,1700,327,315,91,10,2607,427,94 | 1.0834071043843578,1.5608137029341247,1.9696962435077099,-0.023770392974690285,1.1474255928962198,1.1793918752131152,2.094645697510917,3.9257537181006645,-0.5585523596845848,0.9871621278015353,2.094645697510917 | 3,475 |
Positive regulation of mrna splicing via spliceosome | 9 | 17 | 3.033609 | 0.002416 | P62995,Q96E39,Q13573,P98179,Q9Y2W1,P38159,P19338,Q13595,Q14011 | Processes and pathways | GO Biological process | msigdb_gobp | 247,357,280,72,407,74,171,486,56 | 2208,2211,171,2656,74,1285,247,72,1398,280,486,56,595,357,1149,1371,407 | -0.32339579074041863,-0.32339579074041863,1.5608137029341247,-0.6260946606959044,2.3123708840455612,0.24013334861470298,1.3069742818074888,2.343379067489768,0.1743647331482899,1.2432393107605846,0.89065247147567,2.559784134405456,0.7615532030666726,1.0834071043843578,0.33853323249162104,0.2072660552143123,1.0192729716930538 | 3,475 |
Peroxisomes | 13 | 16 | 3.03215 | 0.002428 | P09110,O43808,Q9Y2Q3,Q9BY49,Q8WVX9,P56589,O15254,O00116,O75521,Q15067,O75381,P22307,Q5T8D3 | Localization | Protein Atlas Subcellular | protein_atlas_subcellular_location_all | 246,534,925,167,862,41,169,346,388,315,430,847,658 | 346,169,534,430,388,246,847,1642,940,1489,41,315,658,862,167,925 | 1.0834071043843578,1.5608137029341247,0.8261633820993779,0.9550218762313673,1.0192729716930538,1.3069742818074888,0.5344429793834905,0.009339846996152005,0.4692696641062204,0.10845911446660461,2.775073997044326,1.1793918752131152,0.6968204986884444,0.5344429793834905,1.5924222429530126,0.5018723958328761 | 3,475 |
Organellar ribosome | 32 | 54 | 3.01091 | 0.002605 | Q9BYD1,Q9Y2R9,Q9H2W6,Q9P015,O95182,Q14197,Q13405,P82930,P82673,Q8IXM3,Q13084,Q9NQ50,O75394,Q5T653,Q9NX20,P82912,Q96A35,Q9HD33,Q9Y3B7,Q16540,Q92552,Q96GC5,P52815,P82650,Q9BYD2,Q9BYC9,Q9BZE1,Q9BYD3,P82664,Q567V2,P09001,P82933 | Localization | GO Cellular component | msigdb_gocc | 1056,532,1057,1061,885,774,416,651,538,42,296,61,930,1090,474,694,329,870,345,82,746,1150,87,588,758,361,1016,242,850,853,723,727 | 930,885,723,2223,1710,87,588,850,538,1546,694,1231,651,727,296,416,774,82,853,1090,2018,2492,3277,42,2352,1732,746,329,2550,1248,1150,1810,361,1056,758,242,1016,1057,1968,870,1625,61,2994,1861,474,1679,1061,1867,1162,532,2516,345,2454,1213 | 0.4692696641062204,0.5018723958328761,0.631963801638392,-0.32339579074041863,-0.023770392974690285,2.1258216652317476,0.7615532030666726,0.5344429793834905,0.8261633820993779,0.07545436686033442,0.6644077422188699,0.27296683220001094,0.6968204986884444,0.631963801638392,1.2113297287229814,0.9871621278015353,0.5994884884196273,2.2502835286953093,0.5344429793834905,0.3712665741938593,-0.18986101163713162,-0.4911696283708453,-1.3803273911864882,2.775073997044326,-0.3903896488181674,-0.023770392974690285,0.631963801638392,1.1474255928962198,-0.524841194797217,0.27296683220001094,0.33853323249162104,-0.05691626960112453,1.0834071043843578,0.4039669561578337,0.631963801638392,1.338799977605599,0.4366345847838189,0.4039669561578337,-0.15657014623897816,0.5344429793834905,0.04241468851205189,2.4671777752406974,-0.8979084274692133,-0.09009802404997375,0.922852047787671,0.009339846996152005,0.4039669561578337,-0.09009802404997375,0.33853323249162104,0.8584229744726526,-0.4911696283708453,1.1154307228188172,-0.4575373713799266,0.3057667222448112 | 3,475 |
Positive regulation of rna splicing | 9 | 23 | 2.972344 | 0.002955 | P62995,Q13573,Q96E39,P98179,Q9Y2W1,P38159,P19338,Q13595,Q14011 | Processes and pathways | GO Biological process | msigdb_gobp | 247,280,357,72,407,74,171,486,56 | 2576,2208,2211,171,1778,1779,2656,74,1285,247,72,1398,1084,280,486,56,595,2248,357,1149,1747,1371,407 | -0.5585523596845848,-0.32339579074041863,-0.32339579074041863,1.5608137029341247,-0.05691626960112453,-0.05691626960112453,-0.6260946606959044,2.3123708840455612,0.24013334861470298,1.3069742818074888,2.343379067489768,0.1743647331482899,0.3712665741938593,1.2432393107605846,0.89065247147567,2.559784134405456,0.7615532030666726,-0.32339579074041863,1.0834071043843578,0.33853323249162104,-0.023770392974690285,0.2072660552143123,1.0192729716930538 | 3,475 |
Flavin adenine dinucleotide binding | 9 | 28 | 2.935119 | 0.003334 | O15254,Q8NB78,Q14534,O00116,O95831,P11310,Q15392,Q15067,Q9Y2Z9 | Functions | GO Molecular function | msigdb_gomf | 169,10,327,346,109,89,91,315,94 | 2041,346,169,1828,109,1700,2797,1475,89,2273,616,2047,1034,2423,3187,2171,327,315,91,735,2488,1092,10,1012,2607,868,427,94 | -0.22318875028858487,1.0834071043843578,1.5608137029341247,-0.09009802404997375,1.9696962435077099,-0.023770392974690285,-0.761667607945778,0.10845911446660461,2.094645697510917,-0.3568736241903287,0.7292022575003356,-0.22318875028858487,0.4039669561578337,-0.4575373713799266,-1.1724794204274362,-0.2899558780062751,1.1474255928962198,1.1793918752131152,2.094645697510917,0.631963801638392,-0.4911696283708453,0.3712665741938593,3.9257537181006645,0.4366345847838189,-0.5585523596845848,0.5344429793834905,0.9871621278015353,2.094645697510917 | 3,475 |
Active transmembrane transporter activity | 38 | 81 | 2.921663 | 0.003482 | P08183,O43920,O95169,P41440,O95182,Q9Y5K8,Q9H2J7,P20020,P98194,P08195,Q15758,O43674,O00400,Q9Y289,P06576,O00483,P51790,P13073,P19404,O15439,P20674,O14548,P10606,P55011,Q96ES6,Q9UDW1,Q16795,Q8NE86,P33527,O75489,P03886,O75306,O95168,P36543,O43676,P23634,Q02978,Q9NRK6 | Functions | GO Molecular function | msigdb_gomf | 8,504,16,20,885,554,424,647,159,1032,956,410,409,836,292,800,50,433,938,928,687,188,809,693,83,873,597,1007,587,841,349,347,721,111,613,991,1000,527 | 409,800,188,928,410,613,3343,504,1266,1634,347,3131,1635,841,721,16,885,1327,2372,2159,2421,349,2464,1115,1769,1428,292,8,1032,1771,809,1477,1988,433,1990,1116,938,647,687,1777,2051,991,1642,2470,3114,587,2054,111,1645,20,1487,50,2283,1838,1946,2901,693,2476,159,1714,1000,1492,1043,1239,956,2181,597,1403,1007,83,1965,424,2610,527,2260,2615,873,1465,836,554,2265 | 0.9871621278015353,0.5669816119272515,1.4658276708247233,0.4692696641062204,0.9871621278015353,0.7292022575003356,-1.554860075681201,0.8584229744726526,0.24013334861470298,0.009339846996152005,1.0834071043843578,-1.1035684565388577,0.009339846996152005,0.5344429793834905,0.631963801638392,3.655839397007132,0.5018723958328761,0.2072660552143123,-0.42394413865700914,-0.2899558780062751,-0.4575373713799266,1.0834071043843578,-0.4911696283708453,0.33853323249162104,-0.05691626960112453,0.14142916094516933,1.2113297287229814,3.9556492376216754,0.4039669561578337,-0.05691626960112453,0.5669816119272515,0.10845911446660461,-0.18986101163713162,0.9550218762313673,-0.18986101163713162,0.33853323249162104,0.4692696641062204,0.6968204986884444,0.6644077422188699,-0.05691626960112453,-0.22318875028858487,0.4366345847838189,0.009339846996152005,-0.4911696283708453,-1.0691809388636886,0.7615532030666726,-0.22318875028858487,1.9696962435077099,0.009339846996152005,3.263161715062665,0.10845911446660461,2.621407751431034,-0.3568736241903287,-0.09009802404997375,-0.15657014623897816,-0.8297032421061233,0.6644077422188699,-0.4911696283708453,1.6240042815163254,-0.023770392974690285,0.4366345847838189,0.10845911446660461,0.4039669561578337,0.27296683220001094,0.4692696641062204,-0.2899558780062751,0.7615532030666726,0.1743647331482899,0.4366345847838189,2.2502835286953093,-0.15657014623897816,0.9871621278015353,-0.5585523596845848,0.8584229744726526,-0.32339579074041863,-0.5585523596845848,0.5344429793834905,0.14142916094516933,0.5669816119272515,0.8261633820993779,-0.32339579074041863 | 3,475 |
Intrinsic component of mitochondrial membrane | 15 | 48 | 2.914395 | 0.003564 | O95140,Q96NB2,O60830,Q9Y2R0,Q9Y512,Q99595,Q9BPX6,Q6UXV4,Q16891,O75880,P50416,Q9H9P8,Q9Y3D6,Q9NX63,Q9NRK6 | Localization | GO Cellular component | msigdb_gocc | 244,495,3,67,259,134,240,204,515,291,113,286,52,121,527 | 1426,1071,3,1217,291,1381,244,1876,932,1477,2376,1120,2171,113,1714,1551,2010,1239,735,515,2348,736,1138,204,1657,1804,857,3401,1007,495,134,240,2609,3445,1671,1155,1418,286,1204,527,760,121,1063,1064,67,52,553,259 | 0.14142916094516933,0.3712665741938593,4.902800840805222,0.27296683220001094,1.2113297287229814,0.1743647331482899,1.3069742818074888,-0.12331590050833183,0.4692696641062204,0.10845911446660461,-0.42394413865700914,0.33853323249162104,-0.2899558780062751,1.93839687467804,-0.023770392974690285,0.07545436686033442,-0.18986101163713162,0.27296683220001094,0.631963801638392,0.8584229744726526,-0.3903896488181674,0.631963801638392,0.33853323249162104,1.4341117147858753,0.009339846996152005,-0.05691626960112453,0.5344429793834905,-1.9433641305204705,0.4366345847838189,0.89065247147567,1.8129476360755272,1.338799977605599,-0.5585523596845848,-2.5574276464493524,0.009339846996152005,0.33853323249162104,0.1743647331482899,1.2432393107605846,0.3057667222448112,0.8584229744726526,0.631963801638392,1.9070724559775802,0.4039669561578337,0.4039669561578337,2.405325005947192,2.590607268495023,0.8261633820993779,1.3069742818074888 | 3,475 |
Mrna cis splicing via spliceosome | 9 | 20 | 2.883882 | 0.003928 | Q8WXF0,Q96I25,Q07955,Q9Y2W2,Q9P013,O75475,Q15459,Q9BUQ8,O75400 | Processes and pathways | GO Biological process | msigdb_gobp | 96,708,210,288,57,123,439,757,216 | 982,216,123,1637,724,2117,1335,210,1398,1133,1552,439,1656,96,2783,708,757,1747,57,288 | 0.4366345847838189,1.3705980155545952,1.8757228615346935,0.009339846996152005,0.631963801638392,-0.25655361902926604,0.2072660552143123,1.402368545245139,0.1743647331482899,0.33853323249162104,0.07545436686033442,0.9550218762313673,0.009339846996152005,2.0634452922827657,-0.72771255680608,0.6644077422188699,0.631963801638392,-0.023770392974690285,2.559784134405456,1.2432393107605846 | 3,475 |
Peroxisome | 14 | 33 | 2.871666 | 0.004083 | O15228,P09110,Q9BY49,P48735,P56589,O15254,O75874,O00116,O14734,O75521,Q15067,P34913,Q9NR77,O75381 | Processes and pathways | KEGG Pathways | msigdb_kegg | 365,246,167,5,41,169,75,346,477,388,315,23,118,430 | 346,477,365,169,534,929,430,388,75,1031,886,934,246,847,1642,3142,1782,23,1180,1482,940,5,1489,41,852,3464,315,2908,862,2504,167,118,925 | 1.0834071043843578,0.89065247147567,1.0513545753283584,1.5608137029341247,0.8261633820993779,0.4692696641062204,0.9550218762313673,1.0192729716930538,2.281339075443853,0.4039669561578337,0.5018723958328761,0.4692696641062204,1.3069742818074888,0.5344429793834905,0.009339846996152005,-1.1035684565388577,-0.05691626960112453,3.1720572250461965,0.3057667222448112,0.10845911446660461,0.4692696641062204,4.667687825369334,0.10845911446660461,2.775073997044326,0.5344429793834905,-3.6871244846496367,1.1793918752131152,-0.8297032421061233,0.5344429793834905,-0.4911696283708453,1.5924222429530126,1.93839687467804,0.5018723958328761 | 3,475 |
Skin nodule | 6 | 22 | 2.859671 | 0.004241 | P48735,P35637,O75874,P34913,Q9NZ08,P01889 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 5,191,75,23,25,54 | 75,54,1939,2802,1116,1224,1033,3059,23,1783,191,5,3206,817,3117,3393,1894,1725,1958,1363,25,258 | 2.281339075443853,2.559784134405456,-0.15657014623897816,-0.761667607945778,0.33853323249162104,0.27296683220001094,0.4039669561578337,-1.0005399910393864,3.1720572250461965,-0.05691626960112453,1.4658276708247233,4.667687825369334,-1.2070036199349412,0.5669816119272515,-1.0691809388636886,-1.8722430913337662,-0.12331590050833183,-0.023770392974690285,-0.15657014623897816,0.2072660552143123,3.1720572250461965,1.3069742818074888 | 3,475 |
Cardiac arrest | 7 | 34 | 2.859315 | 0.004246 | P0DP25,O43772,O15460,P50416,P15924,P52815,P01889 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 65,1,162,113,81,87,54 | 162,1936,1,54,432,2374,1383,65,177,81,3059,1944,1180,2627,3187,893,113,87,1129,2065,3147,655,465,3294,2673,1051,668,1669,1623,2449,868,1209,1319,1928 | 1.5924222429530126,-0.15657014623897816,5.514987445868287,2.559784134405456,0.9550218762313673,-0.42394413865700914,0.1743647331482899,2.405325005947192,1.5291785218097205,2.2502835286953093,-1.0005399910393864,-0.15657014623897816,0.3057667222448112,-0.5923034159930741,-1.1724794204274362,0.5018723958328761,1.93839687467804,2.1258216652317476,0.33853323249162104,-0.22318875028858487,-1.1035684565388577,0.6968204986884444,0.922852047787671,-1.4151355272862594,-0.6260946606959044,0.4039669561578337,0.6968204986884444,0.009339846996152005,0.04241468851205189,-0.4575373713799266,0.5344429793834905,0.3057667222448112,0.24013334861470298,-0.12331590050833183 | 3,475 |
Histone | 6 | 11 | 2.846824 | 0.004416 | P16402,P07305,P16104,Q92522,P10412,P16403 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 95,245,103,237,190,227 | 681,1981,245,190,103,95,227,277,2432,237,1367 | 0.6644077422188699,-0.18986101163713162,1.3069742818074888,1.4658276708247233,2.0009706871850725,2.0634452922827657,1.338799977605599,1.2432393107605846,-0.4575373713799266,1.338799977605599,0.2072660552143123 | 3,475 |
Endoplasmic reticulum lumen | 18 | 57 | 2.841096 | 0.004496 | P05067,P30533,Q15293,Q96AY3,O15460,Q86UP2,Q8IXB1,Q14257,P14625,P19022,O75718,Q32P28,Q13217,Q9Y680,O43852,Q9NZ08,Q7Z4H8,O76024 | Localization | GO Cellular component | msigdb_gocc | 274,434,234,400,162,205,398,233,323,262,479,441,461,289,146,25,493,431 | 1825,162,2792,146,1761,1633,479,431,1878,274,2375,3344,1175,990,1176,323,2469,262,2161,1386,2848,1993,1429,2891,508,1480,434,815,2228,2769,2481,851,461,233,1653,1722,234,441,822,1852,493,205,398,1094,2300,3338,2819,400,2607,1961,1669,831,1748,1821,25,1376,289 | -0.09009802404997375,1.5924222429530126,-0.761667607945778,1.7185927649678452,-0.05691626960112453,0.009339846996152005,0.89065247147567,0.9550218762313673,-0.12331590050833183,1.2432393107605846,-0.42394413865700914,-1.554860075681201,0.3057667222448112,0.4366345847838189,0.3057667222448112,1.1474255928962198,-0.4911696283708453,1.275120777065889,-0.2899558780062751,0.1743647331482899,-0.7956643954387234,-0.18986101163713162,0.14142916094516933,-0.8297032421061233,0.8584229744726526,0.10845911446660461,0.9550218762313673,0.5669816119272515,-0.32339579074041863,-0.72771255680608,-0.4911696283708453,0.5344429793834905,0.922852047787671,1.338799977605599,0.009339846996152005,-0.023770392974690285,1.338799977605599,0.9550218762313673,0.5669816119272515,-0.09009802404997375,0.89065247147567,1.4341117147858753,1.0192729716930538,0.3712665741938593,-0.3568736241903287,-1.5198542631539218,-0.761667607945778,1.0192729716930538,-0.5585523596845848,-0.15657014623897816,0.009339846996152005,0.5669816119272515,-0.023770392974690285,-0.05691626960112453,3.1720572250461965,0.2072660552143123,1.2432393107605846 | 3,475 |
Serine hydrolase activity | 7 | 20 | 2.830023 | 0.004654 | Q5JRX3,Q6NTF9,Q16740,O14773,O75976,P42785,Q9HB40 | Functions | GO Molecular function | msigdb_gomf | 105,140,144,290,225,59,30 | 290,429,225,2272,2766,2052,690,59,2586,1285,2228,2341,144,1799,105,140,1348,2402,972,30 | 1.2113297287229814,0.9550218762313673,1.338799977605599,-0.3568736241903287,-0.72771255680608,-0.22318875028858487,0.6644077422188699,2.4671777752406974,-0.5585523596845848,0.24013334861470298,-0.32339579074041863,-0.3903896488181674,1.750070167664919,-0.05691626960112453,2.0009706871850725,1.781521747408495,0.2072660552143123,-0.42394413865700914,0.4692696641062204,3.1112169427024057 | 3,475 |
histone | 6 | 9 | 2.810266 | 0.00495 | P16402,P07305,P16104,Q92522,P10412,P16403 | Functions | Panther Protein class | panther_protein_class | 95,245,103,237,190,227 | 681,245,190,103,95,227,277,237,1367 | 0.6644077422188699,1.3069742818074888,1.4658276708247233,2.0009706871850725,2.0634452922827657,1.338799977605599,1.2432393107605846,1.338799977605599,0.2072660552143123 | 3,475 |
RNA recognition motif domain [IPR000504] | 61 | 120 | 2.808038 | 0.004984 | P62995,Q8IY67,Q9UNP9,Q8IXT5,O43390,Q14966,O15042,P49756,O75494,Q13247,P55795,P31943,P09012,P31942,Q16630,Q15233,P52756,Q9P2K5,P23246,P22626,Q96I25,P19338,P78332,P18615,Q96T58,P98175,Q14011,Q9UKM9,Q13151,O60506,Q01130,P98179,P35637,P09651,Q76FK4,P38159,P52272,Q92804,P52597,Q15056,Q07955,Q86V81,Q8WXF1,Q13242,Q96DH6,Q96T37,Q8WXF0,Q96E39,Q15427,Q9BYG3,Q96PK6,P33240,Q14151,P43243,P23588,Q08170,P08579,Q13595,Q15424,P51991,Q12849 | Sequence | InterPro Domain | interpro_domain | 247,399,405,660,880,395,765,511,387,513,649,889,147,391,899,776,276,307,414,413,708,171,173,45,710,295,56,716,568,802,437,72,191,936,601,74,946,472,947,465,210,211,745,462,343,359,96,357,595,497,107,482,487,849,228,378,226,486,734,619,249 | 1689,2419,765,1379,2369,880,1873,802,387,1980,2371,1938,1174,226,2208,147,936,1384,3028,45,171,413,414,228,1779,1226,391,889,482,191,74,941,849,511,619,946,2117,947,276,649,2118,247,173,1649,295,72,1039,437,2773,3034,210,378,249,1717,568,462,1084,513,2069,1497,486,56,3211,487,1041,395,2979,465,776,734,595,1002,1187,899,1503,1897,601,1139,211,2544,660,399,1143,1660,2248,2132,96,745,472,343,357,1149,708,107,359,710,1201,2087,1517,1966,497,1672,3282,2757,1254,1747,1366,1822,307,2261,1753,1259,716,1630,405,1066,1261,1211,2365,2416 | -0.023770392974690285,-0.4575373713799266,0.5994884884196273,0.1743647331482899,-0.42394413865700914,0.5018723958328761,-0.12331590050833183,0.5669816119272515,1.0192729716930538,-0.18986101163713162,-0.42394413865700914,-0.15657014623897816,0.3057667222448112,1.338799977605599,-0.32339579074041863,1.7185927649678452,0.4692696641062204,0.1743647331482899,-0.9662858408639224,2.7443852320603073,1.5608137029341247,0.9871621278015353,0.9871621278015353,1.338799977605599,-0.05691626960112453,0.27296683220001094,1.0192729716930538,0.5018723958328761,0.89065247147567,1.4658276708247233,2.3123708840455612,0.4692696641062204,0.5344429793834905,0.8584229744726526,0.7292022575003356,0.4692696641062204,-0.25655361902926604,0.4692696641062204,1.2432393107605846,0.6968204986884444,-0.25655361902926604,1.3069742818074888,1.5608137029341247,0.009339846996152005,1.2113297287229814,2.343379067489768,0.4039669561578337,0.9550218762313673,-0.72771255680608,-0.9662858408639224,1.402368545245139,1.0513545753283584,1.3069742818074888,-0.023770392974690285,0.7938735177908782,0.922852047787671,0.3712665741938593,0.8584229744726526,-0.22318875028858487,0.10845911446660461,0.89065247147567,2.559784134405456,-1.2070036199349412,0.89065247147567,0.4039669561578337,1.0192729716930538,-0.8979084274692133,0.922852047787671,0.5994884884196273,0.631963801638392,0.7615532030666726,0.4366345847838189,0.3057667222448112,0.5018723958328761,0.10845911446660461,-0.12331590050833183,0.7615532030666726,0.33853323249162104,1.402368545245139,-0.524841194797217,0.6968204986884444,1.0192729716930538,0.33853323249162104,0.009339846996152005,-0.32339579074041863,-0.25655361902926604,2.0634452922827657,0.631963801638392,0.922852047787671,1.1154307228188172,1.0834071043843578,0.33853323249162104,0.6644077422188699,2.0009706871850725,1.0834071043843578,0.6644077422188699,0.3057667222448112,-0.22318875028858487,0.10845911446660461,-0.15657014623897816,0.89065247147567,0.009339846996152005,-1.3803273911864882,-0.6937989237284957,0.27296683220001094,-0.023770392974690285,0.2072660552143123,-0.05691626960112453,1.2113297287229814,-0.32339579074041863,-0.023770392974690285,0.27296683220001094,0.6644077422188699,0.04241468851205189,1.0192729716930538,0.4039669561578337,0.27296683220001094,0.3057667222448112,-0.3903896488181674,-0.42394413865700914 | 3,475 |
Abnormal arterial physiology | 7 | 27 | 2.798792 | 0.005129 | P05067,O15460,O75844,Q14739,Q9NZ08,P02545,P01889 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 274,162,224,250,25,432,54 | 1584,162,1936,1761,2155,224,54,432,2269,274,1939,686,1993,2850,1783,1944,3206,2059,1129,1130,250,465,1748,25,1319,1756,1928 | 0.04241468851205189,1.5924222429530126,-0.15657014623897816,-0.05691626960112453,-0.2899558780062751,1.338799977605599,2.559784134405456,0.9550218762313673,-0.3568736241903287,1.2432393107605846,-0.15657014623897816,0.6644077422188699,-0.18986101163713162,-0.7956643954387234,-0.05691626960112453,-0.15657014623897816,-1.2070036199349412,-0.22318875028858487,0.33853323249162104,0.33853323249162104,1.3069742818074888,0.922852047787671,-0.023770392974690285,3.1720572250461965,0.24013334861470298,-0.023770392974690285,-0.12331590050833183 | 3,475 |
Formation of senescence associated heterochromatin foci sahf | 6 | 9 | 2.784218 | 0.005366 | Q96L91,P07305,P16402,P10412,P16403,P17096 | Processes and pathways | Reactome Pathways | msigdb_reactome | 358,245,95,190,227,141 | 2269,2046,245,190,95,227,141,374,358 | -0.3568736241903287,-0.22318875028858487,1.3069742818074888,1.4658276708247233,2.0634452922827657,1.338799977605599,1.750070167664919,1.0513545753283584,1.0834071043843578 | 3,475 |
Protein localization to mitochondrion | 20 | 65 | 2.777755 | 0.005474 | O95140,O60830,Q99595,Q9UII2,O14737,O43615,Q9H270,P10809,Q9NS69,Q9HAV7,Q9Y3D6,O43464,P11233,O95817,P0DP25,Q07812,Q5JRX3,O95831,Q9Y512,P55786 | Processes and pathways | GO Biological process | msigdb_gobp | 244,3,134,136,260,273,303,536,39,576,52,429,561,558,65,591,105,109,259,125 | 1166,3251,2459,1111,260,1426,429,273,3,1636,1381,244,2205,1270,558,109,932,2330,65,536,561,1942,2581,2687,772,2936,3059,3060,648,3087,816,2898,125,3090,591,1001,2010,1239,2012,1294,2348,105,2702,2299,784,3401,1197,3214,1458,134,631,2507,303,576,39,2260,1862,2758,136,877,1526,52,259,2456,1929 | 0.3057667222448112,-1.3108557315234917,-0.4911696283708453,0.33853323249162104,1.275120777065889,0.14142916094516933,0.9550218762313673,1.2432393107605846,4.902800840805222,0.009339846996152005,0.1743647331482899,1.3069742818074888,-0.32339579074041863,0.24013334861470298,0.7938735177908782,1.9696962435077099,0.4692696641062204,-0.3903896488181674,2.405325005947192,0.8261633820993779,0.7938735177908782,-0.15657014623897816,-0.5585523596845848,-0.6599263948599569,0.5994884884196273,-0.8637844753937785,-1.0005399910393864,-1.0005399910393864,0.6968204986884444,-1.0348382379290142,0.5669816119272515,-0.8297032421061233,1.8757228615346935,-1.0348382379290142,0.7615532030666726,0.4366345847838189,-0.18986101163713162,0.27296683220001094,-0.18986101163713162,0.24013334861470298,-0.3903896488181674,2.0009706871850725,-0.6599263948599569,-0.3568736241903287,0.5994884884196273,-1.9433641305204705,0.3057667222448112,-1.2070036199349412,0.14142916094516933,1.8129476360755272,0.7292022575003356,-0.4911696283708453,1.2113297287229814,0.7938735177908782,2.8670084338016997,-0.32339579074041863,-0.09009802404997375,-0.6937989237284957,1.8129476360755272,0.5344429793834905,0.10845911446660461,2.590607268495023,1.3069742818074888,-0.4575373713799266,-0.12331590050833183 | 3,475 |
Nucleotide-binding alpha-beta plait domain superfamily [IPR012677] | 59 | 131 | 2.773541 | 0.005545 | P62995,Q8IY67,Q9H501,Q9UNP9,Q8IXT5,Q14966,O15042,P49756,O75494,Q13247,P55795,O95453,P09012,P31942,P52756,Q9P2K5,P23246,P22626,Q96I25,P19338,P78332,P18615,Q96T58,P98175,Q14011,Q9UKM9,Q13151,Q01130,P98179,P35637,Q76FK4,P38159,Q92804,Q15056,Q07955,Q86V81,Q16540,Q8WXF1,Q96DH6,Q13242,Q96T37,Q8WXF0,Q96E39,Q15427,Q9BYG3,Q9BZI7,Q9UKV3,Q96PK6,P33240,Q14151,P23588,Q08170,P08579,Q53F19,Q13595,Q9Y2U8,Q15424,P51991,Q12849 | Sequence | InterPro Superfamily | interpro_homologous_superfamily | 247,399,791,405,660,395,765,511,387,513,649,769,147,391,276,307,414,413,708,171,173,45,710,295,56,716,568,437,72,191,601,74,472,465,210,211,82,745,343,462,359,96,357,595,497,759,499,107,482,487,228,378,226,381,486,258,734,619,249 | 1689,2419,765,1379,2369,880,1873,802,387,1980,2371,769,1938,1174,226,2208,147,936,1384,3028,45,171,413,414,228,1779,1226,391,889,482,191,74,941,849,511,619,946,2117,947,276,649,2118,1183,247,173,1649,295,72,1039,437,2773,3034,210,378,249,1717,568,462,1084,513,2069,1497,486,56,3211,487,1041,395,2979,465,776,734,595,1002,82,1187,899,1503,381,1897,601,1139,211,2544,660,399,1143,1660,2248,2132,96,745,1569,472,343,357,1149,708,107,359,710,1201,2087,1517,1966,497,759,1672,791,3282,2757,1254,1747,1366,1822,307,2261,1062,1753,1259,716,499,1630,405,1066,258,2831,1261,1211,2365,2416 | -0.023770392974690285,-0.4575373713799266,0.5994884884196273,0.1743647331482899,-0.42394413865700914,0.5018723958328761,-0.12331590050833183,0.5669816119272515,1.0192729716930538,-0.18986101163713162,-0.42394413865700914,0.5994884884196273,-0.15657014623897816,0.3057667222448112,1.338799977605599,-0.32339579074041863,1.7185927649678452,0.4692696641062204,0.1743647331482899,-0.9662858408639224,2.7443852320603073,1.5608137029341247,0.9871621278015353,0.9871621278015353,1.338799977605599,-0.05691626960112453,0.27296683220001094,1.0192729716930538,0.5018723958328761,0.89065247147567,1.4658276708247233,2.3123708840455612,0.4692696641062204,0.5344429793834905,0.8584229744726526,0.7292022575003356,0.4692696641062204,-0.25655361902926604,0.4692696641062204,1.2432393107605846,0.6968204986884444,-0.25655361902926604,0.3057667222448112,1.3069742818074888,1.5608137029341247,0.009339846996152005,1.2113297287229814,2.343379067489768,0.4039669561578337,0.9550218762313673,-0.72771255680608,-0.9662858408639224,1.402368545245139,1.0513545753283584,1.3069742818074888,-0.023770392974690285,0.7938735177908782,0.922852047787671,0.3712665741938593,0.8584229744726526,-0.22318875028858487,0.10845911446660461,0.89065247147567,2.559784134405456,-1.2070036199349412,0.89065247147567,0.4039669561578337,1.0192729716930538,-0.8979084274692133,0.922852047787671,0.5994884884196273,0.631963801638392,0.7615532030666726,0.4366345847838189,2.2502835286953093,0.3057667222448112,0.5018723958328761,0.10845911446660461,1.0513545753283584,-0.12331590050833183,0.7615532030666726,0.33853323249162104,1.402368545245139,-0.524841194797217,0.6968204986884444,1.0192729716930538,0.33853323249162104,0.009339846996152005,-0.32339579074041863,-0.25655361902926604,2.0634452922827657,0.631963801638392,0.07545436686033442,0.922852047787671,1.1154307228188172,1.0834071043843578,0.33853323249162104,0.6644077422188699,2.0009706871850725,1.0834071043843578,0.6644077422188699,0.3057667222448112,-0.22318875028858487,0.10845911446660461,-0.15657014623897816,0.89065247147567,0.631963801638392,0.009339846996152005,0.5994884884196273,-1.3803273911864882,-0.6937989237284957,0.27296683220001094,-0.023770392974690285,0.2072660552143123,-0.05691626960112453,1.2113297287229814,-0.32339579074041863,0.4039669561578337,-0.023770392974690285,0.27296683220001094,0.6644077422188699,0.89065247147567,0.04241468851205189,1.0192729716930538,0.4039669561578337,1.3069742818074888,-0.761667607945778,0.27296683220001094,0.3057667222448112,-0.3903896488181674,-0.42394413865700914 | 3,475 |
Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins | 31 | 67 | 2.771205 | 0.005585 | O43920,O95169,P14927,O43674,P06576,O00483,O75880,P56385,P13073,Q8N183,P20674,P24539,O14548,P10606,Q8TB37,Q9H845,Q9Y375,P36542,Q9UDW1,Q16795,P22695,Q12931,Q9BQ95,P03886,O75947,O75306,O95168,P48047,Q9P032,O43676,Q16134 | Processes and pathways | Reactome Pathways | msigdb_reactome | 504,16,40,410,292,800,291,183,433,194,687,688,188,809,471,868,79,456,873,597,586,592,241,349,348,347,721,229,255,613,735 | 800,188,2418,410,613,3343,1071,504,1634,347,1635,841,291,348,3234,721,16,885,2372,2159,2421,3264,349,2464,292,1771,809,433,2273,1990,40,1703,938,687,1224,586,688,1078,2470,2423,3114,456,1118,1079,229,1487,1838,1543,183,592,735,2181,597,3170,194,3401,471,241,3015,868,1059,1209,255,2260,873,79,2265 | 0.5669816119272515,1.4658276708247233,-0.4575373713799266,0.9871621278015353,0.7292022575003356,-1.554860075681201,0.3712665741938593,0.8584229744726526,0.009339846996152005,1.0834071043843578,0.009339846996152005,0.5344429793834905,1.2113297287229814,1.0834071043843578,-1.2761913810585277,0.631963801638392,3.655839397007132,0.5018723958328761,-0.42394413865700914,-0.2899558780062751,-0.4575373713799266,-1.3455675981762987,1.0834071043843578,-0.4911696283708453,1.2113297287229814,-0.05691626960112453,0.5669816119272515,0.9550218762313673,-0.3568736241903287,-0.18986101163713162,2.836385499712057,-0.023770392974690285,0.4692696641062204,0.6644077422188699,0.27296683220001094,0.7615532030666726,0.6644077422188699,0.3712665741938593,-0.4911696283708453,-0.4575373713799266,-1.0691809388636886,0.922852047787671,0.33853323249162104,0.3712665741938593,1.338799977605599,0.10845911446660461,-0.09009802404997375,0.07545436686033442,1.4975165585697592,0.7615532030666726,0.631963801638392,-0.2899558780062751,0.7615532030666726,-1.1380011591326509,1.4658276708247233,-1.9433641305204705,0.922852047787671,1.338799977605599,-0.9320754353215098,0.5344429793834905,0.4039669561578337,0.3057667222448112,1.3069742818074888,-0.32339579074041863,0.5344429793834905,2.281339075443853,-0.32339579074041863 | 3,475 |
Protein targeting to mitochondrion | 12 | 50 | 2.765856 | 0.005677 | O95140,O60830,Q99595,Q9NS69,Q9UII2,Q5JRX3,O95831,O14737,Q9Y3D6,Q9Y512,O43615,P55786 | Processes and pathways | GO Biological process | msigdb_gobp | 244,3,134,39,136,105,109,260,52,259,273,125 | 1166,3251,260,1426,429,273,3,1636,1381,244,2205,1270,558,109,932,2330,536,2581,772,3060,648,3087,816,125,3090,1001,1239,2012,1294,2348,105,2702,2299,784,3214,1458,134,631,2507,303,576,39,2260,1862,2758,136,1526,52,259,2456 | 0.3057667222448112,-1.3108557315234917,1.275120777065889,0.14142916094516933,0.9550218762313673,1.2432393107605846,4.902800840805222,0.009339846996152005,0.1743647331482899,1.3069742818074888,-0.32339579074041863,0.24013334861470298,0.7938735177908782,1.9696962435077099,0.4692696641062204,-0.3903896488181674,0.8261633820993779,-0.5585523596845848,0.5994884884196273,-1.0005399910393864,0.6968204986884444,-1.0348382379290142,0.5669816119272515,1.8757228615346935,-1.0348382379290142,0.4366345847838189,0.27296683220001094,-0.18986101163713162,0.24013334861470298,-0.3903896488181674,2.0009706871850725,-0.6599263948599569,-0.3568736241903287,0.5994884884196273,-1.2070036199349412,0.14142916094516933,1.8129476360755272,0.7292022575003356,-0.4911696283708453,1.2113297287229814,0.7938735177908782,2.8670084338016997,-0.32339579074041863,-0.09009802404997375,-0.6937989237284957,1.8129476360755272,0.10845911446660461,2.590607268495023,1.3069742818074888,-0.4575373713799266 | 3,475 |
Round face | 12 | 22 | 2.751632 | 0.00593 | P82673,Q8IYI6,O75530,Q8WVQ1,O75718,Q96L73,Q32P28,Q03164,P52815,Q69YQ0,P02545,P10644 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 538,702,137,77,479,709,441,458,87,737,432,560 | 137,479,432,935,560,3059,1481,2338,87,538,1438,458,1290,1344,441,737,702,77,785,709,2196,1867 | 1.781521747408495,0.89065247147567,0.9550218762313673,0.4692696641062204,0.7938735177908782,-1.0005399910393864,0.10845911446660461,-0.3903896488181674,2.1258216652317476,0.8261633820993779,0.14142916094516933,0.922852047787671,0.24013334861470298,0.2072660552143123,0.9550218762313673,0.631963801638392,0.6644077422188699,2.281339075443853,0.5994884884196273,0.6644077422188699,-0.2899558780062751,-0.09009802404997375 | 3,475 |
Protein transmembrane import into intracellular organelle | 6 | 12 | 2.742382 | 0.0061 | O60830,P10809,Q99595,O95831,O43615,O75381 | Processes and pathways | GO Biological process | msigdb_gobp | 3,536,134,109,273,430 | 1426,273,3,430,1381,109,932,536,1239,1294,134,576 | 0.14142916094516933,1.2432393107605846,4.902800840805222,0.9550218762313673,0.1743647331482899,1.9696962435077099,0.4692696641062204,0.8261633820993779,0.27296683220001094,0.24013334861470298,1.8129476360755272,0.7938735177908782 | 3,475 |
Primary active transmembrane transporter activity | 25 | 59 | 2.722579 | 0.006477 | P08183,O43920,O95169,O95182,Q9Y5K8,P20020,P98194,O43674,P06576,O00483,P13073,P19404,P20674,O14548,P10606,Q9UDW1,Q16795,P33527,O75489,P03886,O75306,O95168,P36543,O43676,Q9NRK6 | Functions | GO Molecular function | msigdb_gomf | 8,504,16,885,554,647,159,410,292,800,433,938,687,188,809,873,597,587,841,349,347,721,111,613,527 | 800,188,928,410,613,3343,504,1266,1634,347,3131,1635,841,721,16,885,2372,2159,2421,349,2464,1769,292,8,1771,809,433,1990,1116,938,647,687,1777,2051,991,1642,2470,3114,587,2054,111,1645,1487,2283,1838,2476,159,1492,1239,2181,597,1403,2610,527,2260,873,1465,554,2265 | 0.5669816119272515,1.4658276708247233,0.4692696641062204,0.9871621278015353,0.7292022575003356,-1.554860075681201,0.8584229744726526,0.24013334861470298,0.009339846996152005,1.0834071043843578,-1.1035684565388577,0.009339846996152005,0.5344429793834905,0.631963801638392,3.655839397007132,0.5018723958328761,-0.42394413865700914,-0.2899558780062751,-0.4575373713799266,1.0834071043843578,-0.4911696283708453,-0.05691626960112453,1.2113297287229814,3.9556492376216754,-0.05691626960112453,0.5669816119272515,0.9550218762313673,-0.18986101163713162,0.33853323249162104,0.4692696641062204,0.6968204986884444,0.6644077422188699,-0.05691626960112453,-0.22318875028858487,0.4366345847838189,0.009339846996152005,-0.4911696283708453,-1.0691809388636886,0.7615532030666726,-0.22318875028858487,1.9696962435077099,0.009339846996152005,0.10845911446660461,-0.3568736241903287,-0.09009802404997375,-0.4911696283708453,1.6240042815163254,0.10845911446660461,0.27296683220001094,-0.2899558780062751,0.7615532030666726,0.1743647331482899,-0.5585523596845848,0.8584229744726526,-0.32339579074041863,0.5344429793834905,0.14142916094516933,0.8261633820993779,-0.32339579074041863 | 3,475 |
Rhog gtpase cycle | 20 | 37 | 2.715341 | 0.006621 | P84095,P49257,Q5T2T1,Q13190,P50402,Q14126,Q86XL3,O15173,Q07960,P02786,Q86UP2,Q8TAA9,P42167,Q6IAA8,O75489,P61604,P05556,Q9Y2U8,Q14739,P34897 | Processes and pathways | Reactome Pathways | msigdb_reactome | 129,648,778,894,893,655,959,38,184,933,205,604,691,599,841,114,988,258,250,994 | 38,2763,841,1327,1172,933,988,994,1836,691,648,893,2172,2226,2340,114,129,184,1549,1718,894,1237,655,1186,250,2181,778,599,2438,205,959,604,1303,1100,1573,1463,258 | 2.8670084338016997,-0.72771255680608,0.5344429793834905,0.2072660552143123,0.3057667222448112,0.4692696641062204,0.4366345847838189,0.4366345847838189,-0.09009802404997375,0.6644077422188699,0.6968204986884444,0.5018723958328761,-0.2899558780062751,-0.32339579074041863,-0.3903896488181674,1.93839687467804,1.8443479643090066,1.4975165585697592,0.07545436686033442,-0.023770392974690285,0.5018723958328761,0.27296683220001094,0.6968204986884444,0.3057667222448112,1.3069742818074888,-0.2899558780062751,0.5994884884196273,0.7615532030666726,-0.4575373713799266,1.4341117147858753,0.4692696641062204,0.7615532030666726,0.24013334861470298,0.3712665741938593,0.07545436686033442,0.14142916094516933,1.3069742818074888 | 3,475 |
Nucleosome organization | 29 | 58 | 2.712551 | 0.006677 | P07305,Q5SSJ5,Q9NPF5,P17096,P06748,Q9H7B4,P62805,Q969G3,Q96T23,Q8TAQ2,Q92922,Q9Y230,Q9Y5K5,Q9NRF9,Q12830,O75367,Q01105,P10412,P51532,Q92925,Q96GM5,Q8N7H5,Q6ZRS2,P16402,Q9UER7,P16104,Q92522,O14497,P16403 | Processes and pathways | GO Biological process | msigdb_gobp | 245,902,268,141,645,29,277,301,968,573,444,977,978,973,951,681,436,190,945,356,1013,219,491,95,498,103,237,838,227 | 838,1072,984,681,2207,645,245,190,103,95,227,141,1388,2276,2966,1995,1080,2282,945,2474,277,436,2664,1083,951,1342,1549,3353,2979,902,2815,491,1190,219,573,1613,237,2750,444,356,301,1013,968,2356,1739,1741,1623,29,268,973,1205,1206,1367,498,977,2364,2093,978 | 0.5344429793834905,0.3712665741938593,0.4366345847838189,0.6644077422188699,-0.32339579074041863,0.6968204986884444,1.3069742818074888,1.4658276708247233,2.0009706871850725,2.0634452922827657,1.338799977605599,1.750070167664919,0.1743647331482899,-0.3568736241903287,-0.8979084274692133,-0.18986101163713162,0.3712665741938593,-0.3568736241903287,0.4692696641062204,-0.4911696283708453,1.2432393107605846,0.9550218762313673,-0.6260946606959044,0.3712665741938593,0.4692696641062204,0.2072660552143123,0.07545436686033442,-1.5899164189626311,-0.8979084274692133,0.5018723958328761,-0.761667607945778,0.89065247147567,0.3057667222448112,1.3705980155545952,0.7938735177908782,0.04241468851205189,1.338799977605599,-0.6937989237284957,0.9550218762313673,1.0834071043843578,1.2113297287229814,0.4366345847838189,0.4692696641062204,-0.3903896488181674,-0.023770392974690285,-0.023770392974690285,0.04241468851205189,3.1112169427024057,1.275120777065889,0.4692696641062204,0.3057667222448112,0.3057667222448112,0.2072660552143123,0.89065247147567,0.4692696641062204,-0.3903896488181674,-0.22318875028858487,0.4692696641062204 | 3,475 |
Mitochondrial calcium ion transport | 7 | 16 | 2.709416 | 0.00674 | Q9BPX6,P35232,P21796,Q8IYU8,Q99623,Q9UJZ1,Q96TA2 | Processes and pathways | Reactome Pathways | msigdb_reactome | 240,455,110,179,319,364,524 | 1636,1327,110,455,1281,1001,179,1007,1197,1010,524,319,240,364,1927,553 | 0.009339846996152005,0.2072660552143123,1.9696962435077099,0.922852047787671,0.24013334861470298,0.4366345847838189,1.5291785218097205,0.4366345847838189,0.3057667222448112,0.4366345847838189,0.8584229744726526,1.1793918752131152,1.338799977605599,1.0834071043843578,-0.12331590050833183,0.8261633820993779 | 3,475 |
Abnormal circulating fatty acid concentration | 6 | 20 | 2.703944 | 0.006852 | O43772,Q4G0N4,Q16836,P56589,O75880,P11310 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 1,353,165,41,291,89 | 1,430,1217,291,886,1475,89,616,1329,1180,940,1181,3187,1489,1597,41,852,165,353,868 | 5.514987445868287,0.9550218762313673,0.27296683220001094,1.2113297287229814,0.5018723958328761,0.10845911446660461,2.094645697510917,0.7292022575003356,0.2072660552143123,0.3057667222448112,0.4692696641062204,0.3057667222448112,-1.1724794204274362,0.10845911446660461,0.04241468851205189,2.775073997044326,0.5344429793834905,1.5924222429530126,1.0834071043843578,0.5344429793834905 | 3,475 |
Negative regulation of dna recombination | 6 | 16 | 2.701723 | 0.006898 | P16402,P07305,P10412,Q92522,P16403,Q9NRR5 | Processes and pathways | GO Biological process | msigdb_gobp | 95,245,190,237,227,199 | 1424,245,190,95,227,2162,2169,2897,2006,1555,823,1505,237,966,199,402 | 0.14142916094516933,1.3069742818074888,1.4658276708247233,2.0634452922827657,1.338799977605599,-0.2899558780062751,-0.2899558780062751,-0.8297032421061233,-0.18986101163713162,0.07545436686033442,0.5669816119272515,0.10845911446660461,1.338799977605599,0.4692696641062204,1.4658276708247233,1.0192729716930538 | 3,475 |
Abnormality of skull ossification | 6 | 14 | 2.692353 | 0.007095 | P02545,Q04721,O75718,Q32P28,O75844,Q14739 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 432,231,479,441,224,250 | 479,224,432,1386,1711,2854,231,1601,250,1724,1848,441,516,1204 | 0.89065247147567,1.338799977605599,0.9550218762313673,0.1743647331482899,-0.023770392974690285,-0.7956643954387234,1.338799977605599,0.04241468851205189,1.3069742818074888,-0.023770392974690285,-0.09009802404997375,0.9550218762313673,0.8584229744726526,0.3057667222448112 | 3,475 |
Microbody membrane | 15 | 26 | 2.68885 | 0.00717 | O15228,O43808,Q9BY49,O60488,Q8WVX9,P56589,Q6IAN0,O00116,O96011,Q9Y3D6,Q15067,Q9NR77,P04035,O75381,Q5T8D3 | Localization | GO Cellular component | msigdb_gocc | 365,534,167,929,862,41,738,346,886,52,315,118,644,430,658 | 346,365,534,929,430,1031,886,644,3027,1642,1782,1482,940,2173,1489,41,315,658,738,2245,2078,862,2874,167,118,52 | 1.0834071043843578,1.0513545753283584,0.8261633820993779,0.4692696641062204,0.9550218762313673,0.4039669561578337,0.5018723958328761,0.6968204986884444,-0.9662858408639224,0.009339846996152005,-0.05691626960112453,0.10845911446660461,0.4692696641062204,-0.2899558780062751,0.10845911446660461,2.775073997044326,1.1793918752131152,0.6968204986884444,0.631963801638392,-0.32339579074041863,-0.22318875028858487,0.5344429793834905,-0.7956643954387234,1.5924222429530126,1.93839687467804,2.590607268495023 | 3,475 |
Intermediate filament | 8 | 19 | 2.679205 | 0.00738 | Q9H307,P08670,P07197,P14923,P15924,P20700,P02545,Q03252 | Localization | GO Cellular component | msigdb_gocc | 526,71,202,177,81,374,432,311 | 2103,432,202,71,177,81,374,812,2115,1434,512,1491,311,954,821,2020,526,3076,2039 | -0.25655361902926604,0.9550218762313673,1.4341117147858753,2.343379067489768,1.5291785218097205,2.2502835286953093,1.0513545753283584,0.5669816119272515,-0.25655361902926604,0.14142916094516933,0.8584229744726526,0.10845911446660461,1.1793918752131152,0.4692696641062204,0.5669816119272515,-0.18986101163713162,0.8584229744726526,-1.0005399910393864,-0.18986101163713162 | 3,475 |
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