term
stringlengths
2
121
overlap
int64
6
281
setsize
int64
7
499
score
float64
1.96
10.6
pval
float64
0
0.05
edge
stringlengths
41
1.97k
type
stringclasses
5 values
subtype
stringclasses
24 values
subtype_key
stringclasses
24 values
edge_idxs
stringlengths
11
1.17k
ann_idxs
stringlengths
19
2.31k
ann_vals
stringlengths
124
9.94k
sig_size
int64
2.2k
3.73k
Tetrapyrrole binding
7
17
2.672074
0.007538
Q8WUJ1,O15173,Q16850,Q9H7Z7,Q8WYQ5,O00264,P30519
Functions
GO Molecular function
msigdb_gomf
4,38,328,180,149,337,62
337,38,3342,1771,646,2163,62,2900,328,397,4,149,913,2086,180,3074,1164
1.1154307228188172,2.8670084338016997,-1.554860075681201,-0.05691626960112453,0.6968204986884444,-0.2899558780062751,2.4362629820604664,-0.8297032421061233,1.1474255928962198,1.0192729716930538,4.814759722518884,1.7185927649678452,0.5018723958328761,-0.22318875028858487,1.5291785218097205,-1.0005399910393864,0.33853323249162104
3,475
Hcmv late events
21
38
2.671784
0.007545
Q99567,Q8N1F7,Q9Y3E7,P35658,P37198,P12270,Q9BTX1,P62805,P57740,Q9H444,Q96FZ7,Q9H9H4,Q9HD42,P49790,Q8WUM0,Q8TEM1,O15504,Q9UKX7,Q7Z3B4,Q9UQN3,Q9BVL2
Processes and pathways
Reactome Pathways
msigdb_reactome
667,906,679,891,392,771,422,277,650,168,829,304,198,814,1008,1146,583,1022,740,1160,116
583,1765,771,891,392,814,1122,1285,650,1436,277,2771,1843,2292,740,906,1806,1903,1146,1008,1244,1661,2134,829,667,2309,2190,422,116,1621,168,304,198,1420,1022,1823,1160,679
0.7615532030666726,-0.05691626960112453,0.5994884884196273,0.5018723958328761,1.0192729716930538,0.5669816119272515,0.33853323249162104,0.24013334861470298,0.6968204986884444,0.14142916094516933,1.2432393107605846,-0.72771255680608,-0.09009802404997375,-0.3568736241903287,0.631963801638392,0.5018723958328761,-0.05691626960112453,-0.12331590050833183,0.33853323249162104,0.4366345847838189,0.27296683220001094,0.009339846996152005,-0.25655361902926604,0.5669816119272515,0.6968204986884444,-0.3568736241903287,-0.2899558780062751,0.9871621278015353,1.93839687467804,0.04241468851205189,1.5924222429530126,1.2113297287229814,1.4658276708247233,0.1743647331482899,0.4366345847838189,-0.05691626960112453,0.33853323249162104,0.6968204986884444
3,475
Disproportionate short limb short stature
9
21
2.665298
0.007692
O15228,O00116,Q8WVQ1,O75718,Q32P28,Q14696,Q03164,Q15392,Q14739
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
365,346,77,479,441,148,458,91,250
346,365,2462,479,560,1386,1483,2281,458,2666,148,250,2072,91,441,1296,1350,3039,77,2498,1863
1.0834071043843578,1.0513545753283584,-0.4911696283708453,0.89065247147567,0.7938735177908782,0.1743647331482899,0.10845911446660461,-0.3568736241903287,0.922852047787671,-0.6260946606959044,1.7185927649678452,1.3069742818074888,-0.22318875028858487,2.094645697510917,0.9550218762313673,0.24013334861470298,0.2072660552143123,-0.9662858408639224,2.281339075443853,-0.4911696283708453,-0.09009802404997375
3,475
calmodulin-related
6
13
2.648185
0.008093
P0DP25,Q15293,Q9BPX6,Q8IYU8,O43852,Q9BRK5
Functions
Panther Protein class
panther_protein_class
65,234,240,179,146,197
146,65,2584,2967,617,1287,2481,233,234,179,912,240,197
1.7185927649678452,2.405325005947192,-0.5585523596845848,-0.8979084274692133,0.7292022575003356,0.24013334861470298,-0.4911696283708453,1.338799977605599,1.338799977605599,1.5291785218097205,0.5018723958328761,1.338799977605599,1.4658276708247233
3,475
Cation transmembrane transporter activity
28
73
2.620299
0.008785
O43772,Q70HW3,P30825,Q9Y5K8,Q9H2J7,P20020,P98194,O43808,O00400,Q9Y289,P06576,Q99808,P51790,P56385,P13073,Q9Y619,P07355,P20674,P24539,O14548,P10606,P55011,P36542,Q96ES6,Q96NB2,O75947,P36543,P48047
Functions
GO Molecular function
msigdb_gomf
1,781,509,554,424,647,159,534,409,836,292,711,50,183,433,187,559,687,688,188,809,693,456,83,495,348,111,229
409,188,1,534,3131,348,3234,1327,2421,3264,1769,1428,292,559,1831,1032,1771,809,1477,433,1990,1116,647,687,1777,2051,991,688,1078,509,3114,2054,456,111,1645,229,50,693,1543,183,2476,1435,159,1714,3062,1793,1043,956,957,2351,781,1300,1007,3419,1856,1411,83,495,711,1965,1308,424,1418,1204,2610,2718,873,1465,976,836,2567,554,187
0.9871621278015353,1.4658276708247233,5.514987445868287,0.8261633820993779,-1.1035684565388577,1.0834071043843578,-1.2761913810585277,0.2072660552143123,-0.4575373713799266,-1.3455675981762987,-0.05691626960112453,0.14142916094516933,1.2113297287229814,0.7938735177908782,-0.09009802404997375,0.4039669561578337,-0.05691626960112453,0.5669816119272515,0.10845911446660461,0.9550218762313673,-0.18986101163713162,0.33853323249162104,0.6968204986884444,0.6644077422188699,-0.05691626960112453,-0.22318875028858487,0.4366345847838189,0.6644077422188699,0.3712665741938593,0.8584229744726526,-1.0691809388636886,-0.22318875028858487,0.922852047787671,1.9696962435077099,0.009339846996152005,1.338799977605599,2.621407751431034,0.6644077422188699,0.07545436686033442,1.4975165585697592,-0.4911696283708453,0.14142916094516933,1.6240042815163254,-0.023770392974690285,-1.0005399910393864,-0.05691626960112453,0.4039669561578337,0.4692696641062204,0.4692696641062204,-0.3903896488181674,0.5994884884196273,0.24013334861470298,0.4366345847838189,-2.1221574417772153,-0.09009802404997375,0.1743647331482899,2.2502835286953093,0.89065247147567,0.6644077422188699,-0.15657014623897816,0.24013334861470298,0.9871621278015353,0.1743647331482899,0.3057667222448112,-0.5585523596845848,-0.6599263948599569,0.5344429793834905,0.14142916094516933,0.4692696641062204,0.5669816119272515,-0.524841194797217,0.8261633820993779,1.4975165585697592
3,475
Nuclear inner membrane
9
23
2.613236
0.008969
P62995,O76062,Q9UH99,Q99720,O75844,Q9Y2U8,Q14728,Q14739,Q03252
Localization
GO Cellular component
msigdb_gocc
247,69,85,17,224,258,314,250,311
224,69,682,374,1079,849,893,3379,247,311,1185,314,250,1045,1346,3260,2673,2306,17,1669,2648,85,258
1.338799977605599,2.343379067489768,0.6644077422188699,1.0513545753283584,0.3712665741938593,0.5344429793834905,0.5018723958328761,-1.765972455067393,1.3069742818074888,1.1793918752131152,0.3057667222448112,1.1793918752131152,1.3069742818074888,0.4039669561578337,0.2072660552143123,-1.3108557315234917,-0.6260946606959044,-0.3568736241903287,3.655839397007132,0.009339846996152005,-0.5923034159930741,2.2502835286953093,1.3069742818074888
3,475
Mitochondrial large ribosomal subunit
22
37
2.611188
0.009023
Q9BYD1,Q9H2W6,Q9P015,Q14197,Q13405,Q8IXM3,Q13084,Q9NQ50,O75394,Q5T653,Q9NX20,Q96A35,Q9HD33,Q9Y3B7,Q16540,P52815,Q9BYC9,Q9BYD2,Q9BZE1,Q9BYD3,Q567V2,P09001
Localization
GO Cellular component
msigdb_gocc
1056,1057,1061,774,416,42,296,61,930,1090,474,329,870,345,82,87,361,758,1016,242,853,723
930,723,2223,87,296,416,774,82,853,1090,2018,2492,3277,42,2352,1732,329,2550,1248,1150,1810,361,1056,758,242,1016,1057,1968,870,1625,61,2994,1861,474,1679,1061,345
0.4692696641062204,0.631963801638392,-0.32339579074041863,2.1258216652317476,1.2113297287229814,0.9871621278015353,0.5994884884196273,2.2502835286953093,0.5344429793834905,0.3712665741938593,-0.18986101163713162,-0.4911696283708453,-1.3803273911864882,2.775073997044326,-0.3903896488181674,-0.023770392974690285,1.1474255928962198,-0.524841194797217,0.27296683220001094,0.33853323249162104,-0.05691626960112453,1.0834071043843578,0.4039669561578337,0.631963801638392,1.338799977605599,0.4366345847838189,0.4039669561578337,-0.15657014623897816,0.5344429793834905,0.04241468851205189,2.4671777752406974,-0.8979084274692133,-0.09009802404997375,0.922852047787671,0.009339846996152005,0.4039669561578337,1.1154307228188172
3,475
Electron transport chain oxphos system in mitochondria
24
53
2.609797
0.00906
Q9UII2,O43920,O95169,P14927,O43674,P06576,O00483,O75880,P56385,P13073,P20674,P24539,O14548,P10606,P36542,Q9UDW1,Q16795,P22695,P03886,O75947,O75306,O95168,P48047,O43676
Processes and pathways
WikiPathways
msigdb_wp
136,504,16,40,410,292,800,291,183,433,687,688,188,809,456,873,597,586,349,348,347,721,229,613
800,188,2418,410,613,3343,504,1634,347,1635,841,291,348,3234,721,16,885,2372,2159,2421,3264,349,2464,1428,292,809,1477,1988,433,1989,1990,40,1703,938,687,1224,586,688,1078,2470,2423,3114,456,229,1487,1838,1543,183,2181,597,873,136,2265
0.5669816119272515,1.4658276708247233,-0.4575373713799266,0.9871621278015353,0.7292022575003356,-1.554860075681201,0.8584229744726526,0.009339846996152005,1.0834071043843578,0.009339846996152005,0.5344429793834905,1.2113297287229814,1.0834071043843578,-1.2761913810585277,0.631963801638392,3.655839397007132,0.5018723958328761,-0.42394413865700914,-0.2899558780062751,-0.4575373713799266,-1.3455675981762987,1.0834071043843578,-0.4911696283708453,0.14142916094516933,1.2113297287229814,0.5669816119272515,0.10845911446660461,-0.18986101163713162,0.9550218762313673,-0.18986101163713162,-0.18986101163713162,2.836385499712057,-0.023770392974690285,0.4692696641062204,0.6644077422188699,0.27296683220001094,0.7615532030666726,0.6644077422188699,0.3712665741938593,-0.4911696283708453,-0.4575373713799266,-1.0691809388636886,0.922852047787671,1.338799977605599,0.10845911446660461,-0.09009802404997375,0.07545436686033442,1.4975165585697592,-0.2899558780062751,0.7615532030666726,0.5344429793834905,1.8129476360755272,-0.32339579074041863
3,475
Membrane protein proteolysis
6
12
2.607163
0.00913
Q13464,Q9UKS6,P38159,Q16740,Q92542,Q9NZ08
Processes and pathways
GO Biological process
msigdb_gobp
152,333,74,144,520,25
3106,1887,74,152,144,1145,1733,520,25,333,553,1470
-1.0691809388636886,-0.12331590050833183,2.3123708840455612,1.6870894061892987,1.750070167664919,0.33853323249162104,-0.023770392974690285,0.8584229744726526,3.1720572250461965,1.1474255928962198,0.8261633820993779,0.14142916094516933
3,475
mRNA processing factor
38
83
2.60688
0.009137
P62995,Q8IY67,O95391,O15042,O75494,Q13247,O95453,P09012,P23246,Q96I25,P19338,Q8IWZ8,Q14011,Q15459,Q01130,O60508,P98179,P35637,Q92804,P38159,O75525,Q96PU8,Q07955,Q13242,Q8WXF1,Q15637,O43395,Q07666,Q8WXF0,Q96E39,Q96PK6,P33240,Q08170,P08579,P62310,Q13595,Q96SI9,Q96KR1
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
247,399,506,765,387,513,769,147,414,708,171,572,56,439,437,189,72,191,472,74,201,751,210,462,745,596,584,590,96,357,107,482,378,226,484,486,523,789
765,1632,584,1873,1028,189,387,201,842,1268,2045,2371,506,769,226,2208,147,937,171,414,482,191,74,2661,1394,484,2902,1544,3444,3224,247,1649,72,437,2773,590,210,378,1398,1716,1133,1496,1440,1548,462,1084,513,486,56,2979,776,2396,2347,439,596,3212,1187,2540,1656,572,856,399,3278,1147,96,745,472,357,3215,708,789,107,751,523,1517,1575,2677,2359,922,3299,1066,1211,3372
0.5994884884196273,0.009339846996152005,0.7615532030666726,-0.12331590050833183,0.4039669561578337,1.4658276708247233,1.0192729716930538,1.4341117147858753,0.5344429793834905,0.24013334861470298,-0.22318875028858487,-0.42394413865700914,0.8584229744726526,0.5994884884196273,1.338799977605599,-0.32339579074041863,1.7185927649678452,0.4692696641062204,1.5608137029341247,0.9871621278015353,0.89065247147567,1.4658276708247233,2.3123708840455612,-0.6260946606959044,0.1743647331482899,0.89065247147567,-0.8297032421061233,0.07545436686033442,-2.5574276464493524,-1.2415741430250644,1.3069742818074888,0.009339846996152005,2.343379067489768,0.9550218762313673,-0.72771255680608,0.7615532030666726,1.402368545245139,1.0513545753283584,0.1743647331482899,-0.023770392974690285,0.33853323249162104,0.10845911446660461,0.14142916094516933,0.07545436686033442,0.922852047787671,0.3712665741938593,0.8584229744726526,0.89065247147567,2.559784134405456,-0.8979084274692133,0.5994884884196273,-0.42394413865700914,-0.3903896488181674,0.9550218762313673,0.7615532030666726,-1.2070036199349412,0.3057667222448112,-0.524841194797217,0.009339846996152005,0.7938735177908782,0.5344429793834905,1.0192729716930538,-1.3803273911864882,0.33853323249162104,2.0634452922827657,0.631963801638392,0.922852047787671,1.0834071043843578,-1.2070036199349412,0.6644077422188699,0.5994884884196273,2.0009706871850725,0.631963801638392,0.8584229744726526,0.10845911446660461,0.07545436686033442,-0.6260946606959044,-0.3903896488181674,0.5018723958328761,-1.4151355272862594,0.4039669561578337,0.3057667222448112,-1.6953932674425685
3,475
Transport of mature transcript to cytoplasm
32
66
2.601933
0.00927
Q9Y3Y2,Q99567,Q8N1F7,P82979,O95391,Q13247,P35658,P37198,O75152,P12270,Q9UBU9,Q9BTX1,Q96FV9,P57740,Q92797,P49790,Q01130,O60508,Q07955,Q13242,Q86V81,Q13243,Q8WUM0,O15504,Q9UKX7,Q9BZI7,Q7Z3B4,Q6UN15,Q08170,Q9BVL2,Q6I9Y2,Q9P2I0
Processes and pathways
Reactome Pathways
msigdb_reactome
272,667,906,139,506,513,891,392,640,771,1062,422,966,650,1096,814,437,189,210,462,211,1084,1008,583,1022,759,740,112,378,116,126,921
2619,583,189,640,1765,506,1880,771,1779,891,392,2113,814,1122,2117,1285,650,2771,139,1649,437,3034,210,378,1398,1716,1843,462,1084,513,3382,1845,1187,2292,126,112,740,211,2022,3278,906,1806,1903,2080,1146,1008,1246,1661,1096,2134,966,2308,667,422,116,1621,1966,759,2677,1420,921,1062,1369,1022,272,2365
-0.5923034159930741,0.7615532030666726,1.4658276708247233,0.6968204986884444,-0.05691626960112453,0.8584229744726526,-0.12331590050833183,0.5994884884196273,-0.05691626960112453,0.5018723958328761,1.0192729716930538,-0.25655361902926604,0.5669816119272515,0.33853323249162104,-0.25655361902926604,0.24013334861470298,0.6968204986884444,-0.72771255680608,1.781521747408495,0.009339846996152005,0.9550218762313673,-0.9662858408639224,1.402368545245139,1.0513545753283584,0.1743647331482899,-0.023770392974690285,-0.09009802404997375,0.922852047787671,0.3712665741938593,0.8584229744726526,-1.8013419107859299,-0.09009802404997375,0.3057667222448112,-0.3568736241903287,1.8757228615346935,1.9696962435077099,0.631963801638392,1.402368545245139,-0.18986101163713162,-1.3803273911864882,0.5018723958328761,-0.05691626960112453,-0.12331590050833183,-0.22318875028858487,0.33853323249162104,0.4366345847838189,0.27296683220001094,0.009339846996152005,0.3712665741938593,-0.25655361902926604,0.4692696641062204,-0.3568736241903287,0.6968204986884444,0.9871621278015353,1.93839687467804,0.04241468851205189,-0.15657014623897816,0.631963801638392,-0.6260946606959044,0.1743647331482899,0.5018723958328761,0.4039669561578337,0.2072660552143123,0.4366345847838189,1.275120777065889,-0.3903896488181674
3,475
Presynaptic active zone
7
17
2.588381
0.009643
P05067,O14795,P56545,P19022,P41440,Q07021,Q99623
Localization
GO Cellular component
msigdb_gocc
274,102,326,262,20,376,319
102,882,480,274,262,647,991,1429,1783,20,326,376,1650,2775,2868,319,2148
2.0009706871850725,0.5018723958328761,0.89065247147567,1.2432393107605846,1.275120777065889,0.6968204986884444,0.4366345847838189,0.14142916094516933,-0.05691626960112453,3.263161715062665,1.1474255928962198,1.0513545753283584,0.009339846996152005,-0.72771255680608,-0.7956643954387234,1.1793918752131152,-0.25655361902926604
3,475
RNA-binding domain superfamily [IPR035979]
73
133
2.584007
0.009766
P62995,Q8IY67,Q9UNP9,Q8IXT5,O43390,Q14966,O15042,P49756,O75494,Q9UPN6,Q13247,Q9UBU9,P55795,P09012,O95453,P31943,Q15233,P31942,Q16630,P52756,Q9P2K5,P23246,Q14498,P22626,Q96I25,P19338,P78332,P18615,Q96T58,P98175,Q14011,Q9UKM9,Q13151,O60506,Q01130,P98179,P35637,P09651,Q76FK4,P38159,P52272,Q92804,P52597,Q9BXP5,Q15056,Q07955,Q86V81,Q8WXF1,Q13242,Q96DH6,P42696,Q96T37,Q8WXF0,Q96E39,Q15427,Q9BYG3,Q9BZI7,Q9UKV3,Q96PK6,P33240,Q14151,P43243,P23588,Q08170,P08579,Q15717,O60318,Q9BQ39,Q13595,Q9Y2U8,Q15424,P51991,Q12849
Sequence
InterPro Superfamily
interpro_homologous_superfamily
247,399,405,660,880,395,765,511,387,1066,513,1062,649,147,769,889,776,391,899,276,307,414,1041,413,708,171,173,45,710,295,56,716,568,802,437,72,191,936,601,74,946,472,947,608,465,210,211,745,462,343,941,359,96,357,595,497,759,499,107,482,487,849,228,378,226,1002,984,916,486,258,734,619,249
1689,2419,765,1379,2369,880,1873,984,802,387,1980,2371,769,1938,1174,226,2208,147,936,1384,3028,45,171,413,414,228,1779,1226,391,889,482,191,74,941,849,511,619,946,2117,947,276,649,2118,247,173,1649,295,72,1039,437,2773,1437,3034,210,378,249,1717,568,462,1084,513,2069,1497,486,56,3211,487,1041,395,2979,465,776,734,595,1002,1187,899,1503,1897,2243,601,1139,211,2544,660,399,1143,1660,2248,2132,96,745,1569,472,343,357,1149,708,107,359,710,1201,916,2087,1517,608,1966,497,759,1672,3282,1626,2757,1254,1747,1366,1822,307,2261,1062,1753,1259,716,499,1630,405,1066,258,2831,1261,1211,2365,2416
-0.023770392974690285,-0.4575373713799266,0.5994884884196273,0.1743647331482899,-0.42394413865700914,0.5018723958328761,-0.12331590050833183,0.4366345847838189,0.5669816119272515,1.0192729716930538,-0.18986101163713162,-0.42394413865700914,0.5994884884196273,-0.15657014623897816,0.3057667222448112,1.338799977605599,-0.32339579074041863,1.7185927649678452,0.4692696641062204,0.1743647331482899,-0.9662858408639224,2.7443852320603073,1.5608137029341247,0.9871621278015353,0.9871621278015353,1.338799977605599,-0.05691626960112453,0.27296683220001094,1.0192729716930538,0.5018723958328761,0.89065247147567,1.4658276708247233,2.3123708840455612,0.4692696641062204,0.5344429793834905,0.8584229744726526,0.7292022575003356,0.4692696641062204,-0.25655361902926604,0.4692696641062204,1.2432393107605846,0.6968204986884444,-0.25655361902926604,1.3069742818074888,1.5608137029341247,0.009339846996152005,1.2113297287229814,2.343379067489768,0.4039669561578337,0.9550218762313673,-0.72771255680608,0.14142916094516933,-0.9662858408639224,1.402368545245139,1.0513545753283584,1.3069742818074888,-0.023770392974690285,0.7938735177908782,0.922852047787671,0.3712665741938593,0.8584229744726526,-0.22318875028858487,0.10845911446660461,0.89065247147567,2.559784134405456,-1.2070036199349412,0.89065247147567,0.4039669561578337,1.0192729716930538,-0.8979084274692133,0.922852047787671,0.5994884884196273,0.631963801638392,0.7615532030666726,0.4366345847838189,0.3057667222448112,0.5018723958328761,0.10845911446660461,-0.12331590050833183,-0.32339579074041863,0.7615532030666726,0.33853323249162104,1.402368545245139,-0.524841194797217,0.6968204986884444,1.0192729716930538,0.33853323249162104,0.009339846996152005,-0.32339579074041863,-0.25655361902926604,2.0634452922827657,0.631963801638392,0.07545436686033442,0.922852047787671,1.1154307228188172,1.0834071043843578,0.33853323249162104,0.6644077422188699,2.0009706871850725,1.0834071043843578,0.6644077422188699,0.3057667222448112,0.5018723958328761,-0.22318875028858487,0.10845911446660461,0.7615532030666726,-0.15657014623897816,0.89065247147567,0.631963801638392,0.009339846996152005,-1.3803273911864882,0.04241468851205189,-0.6937989237284957,0.27296683220001094,-0.023770392974690285,0.2072660552143123,-0.05691626960112453,1.2113297287229814,-0.32339579074041863,0.4039669561578337,-0.023770392974690285,0.27296683220001094,0.6644077422188699,0.89065247147567,0.04241468851205189,1.0192729716930538,0.4039669561578337,1.3069742818074888,-0.761667607945778,0.27296683220001094,0.3057667222448112,-0.3903896488181674,-0.42394413865700914
3,475
Histone methylation
15
58
2.581283
0.009843
P51608,Q13573,P16402,P02545,Q9Y3Y2,P10412,O75530,P18615,Q96ST2,P16403,O96028,Q5VTR2,Q5T5X7,Q9H7B4,Q8N7H5
Processes and pathways
GO Biological process
msigdb_gobp
310,280,95,432,272,190,137,45,446,227,182,418,24,29,219
1825,3221,1379,1934,1070,1828,840,681,137,182,432,190,95,227,45,1478,2216,1783,3085,310,2690,2533,458,1083,280,2777,3036,1344,2238,657,24,823,418,903,3169,1802,1190,2403,2781,219,2301,2442,2306,788,709,446,3371,1415,2034,1310,29,2137,1749,2789,1681,2510,272,1582
-0.09009802404997375,-1.2415741430250644,0.1743647331482899,-0.15657014623897816,0.3712665741938593,-0.09009802404997375,0.5344429793834905,0.6644077422188699,1.781521747408495,1.4975165585697592,0.9550218762313673,1.4658276708247233,2.0634452922827657,1.338799977605599,2.7443852320603073,0.10845911446660461,-0.32339579074041863,-0.05691626960112453,-1.0348382379290142,1.1793918752131152,-0.6599263948599569,-0.524841194797217,0.922852047787671,0.3712665741938593,1.2432393107605846,-0.72771255680608,-0.9662858408639224,0.2072660552143123,-0.32339579074041863,0.6968204986884444,3.1720572250461965,0.5669816119272515,0.9871621278015353,0.5018723958328761,-1.1380011591326509,-0.05691626960112453,0.3057667222448112,-0.42394413865700914,-0.72771255680608,1.3705980155545952,-0.3568736241903287,-0.4575373713799266,-0.3568736241903287,0.5994884884196273,0.6644077422188699,0.9550218762313673,-1.6953932674425685,0.1743647331482899,-0.18986101163713162,0.24013334861470298,3.1112169427024057,-0.25655361902926604,-0.023770392974690285,-0.72771255680608,0.009339846996152005,-0.4911696283708453,1.275120777065889,0.07545436686033442
3,475
SLC superfamily of solute carriers
19
45
2.576266
0.009987
O43772,Q6NUK1,Q9H2V7,Q70HW3,P30825,Q9UJS0,Q9NZJ7,P41440,Q8IXU6,Q9H2J7,O43808,O00400,Q9Y289,Q99808,Q9Y619,P55011,Q6N075,Q96NB2,Q6P1M0
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
1,516,135,781,509,677,675,20,21,424,534,409,836,711,187,693,697,495,739
409,1,534,806,1327,1876,1115,1428,1032,2625,1477,1988,509,20,1946,2901,693,1714,1000,1043,956,697,516,739,781,21,3419,2081,495,711,970,1965,1308,3196,424,135,1418,1204,675,2615,677,836,1164,187,1929
0.9871621278015353,5.514987445868287,0.8261633820993779,0.5669816119272515,0.2072660552143123,-0.12331590050833183,0.33853323249162104,0.14142916094516933,0.4039669561578337,-0.5923034159930741,0.10845911446660461,-0.18986101163713162,0.8584229744726526,3.263161715062665,-0.15657014623897816,-0.8297032421061233,0.6644077422188699,-0.023770392974690285,0.4366345847838189,0.4039669561578337,0.4692696641062204,0.6644077422188699,0.8584229744726526,0.631963801638392,0.5994884884196273,3.263161715062665,-2.1221574417772153,-0.22318875028858487,0.89065247147567,0.6644077422188699,0.4692696641062204,-0.15657014623897816,0.24013334861470298,-1.1724794204274362,0.9871621278015353,1.8129476360755272,0.1743647331482899,0.3057667222448112,0.6968204986884444,-0.5585523596845848,0.6968204986884444,0.5669816119272515,0.33853323249162104,1.4975165585697592,-0.12331590050833183
3,475
Active ion transmembrane transporter activity
22
47
2.57044
0.010157
P41440,Q9Y5K8,Q9H2J7,P20020,P98194,P08195,O00400,Q9Y289,P06576,P51790,P13073,O15439,P20674,O14548,P10606,P55011,Q96ES6,Q9UDW1,P33527,P36543,P23634,Q02978
Functions
GO Molecular function
msigdb_gomf
20,554,424,647,159,1032,409,836,292,50,433,928,687,188,809,693,83,873,587,111,991,1000
409,188,928,3131,1327,2421,1115,1769,1428,292,1032,1771,809,1477,1988,433,1990,1116,647,687,1777,2051,991,3114,587,2054,111,1645,20,50,2283,1946,693,2476,159,1714,1000,1043,1403,83,1965,424,2610,873,1465,836,554
0.9871621278015353,1.4658276708247233,0.4692696641062204,-1.1035684565388577,0.2072660552143123,-0.4575373713799266,0.33853323249162104,-0.05691626960112453,0.14142916094516933,1.2113297287229814,0.4039669561578337,-0.05691626960112453,0.5669816119272515,0.10845911446660461,-0.18986101163713162,0.9550218762313673,-0.18986101163713162,0.33853323249162104,0.6968204986884444,0.6644077422188699,-0.05691626960112453,-0.22318875028858487,0.4366345847838189,-1.0691809388636886,0.7615532030666726,-0.22318875028858487,1.9696962435077099,0.009339846996152005,3.263161715062665,2.621407751431034,-0.3568736241903287,-0.15657014623897816,0.6644077422188699,-0.4911696283708453,1.6240042815163254,-0.023770392974690285,0.4366345847838189,0.4039669561578337,0.1743647331482899,2.2502835286953093,-0.15657014623897816,0.9871621278015353,-0.5585523596845848,0.5344429793834905,0.14142916094516933,0.5669816119272515,0.8261633820993779
3,475
Peroxisomal lipid metabolism
9
12
2.560833
0.010442
P09110,O43808,Q9BY49,O15254,O14734,O75521,Q15067,P22307,Q5T8D3
Processes and pathways
Reactome Pathways
msigdb_reactome
246,534,167,169,477,388,315,847,658
477,169,534,388,246,847,2173,1489,852,315,658,167
0.89065247147567,1.5608137029341247,0.8261633820993779,1.0192729716930538,1.3069742818074888,0.5344429793834905,-0.2899558780062751,0.10845911446660461,0.5344429793834905,1.1793918752131152,0.6968204986884444,1.5924222429530126
3,475
Dna packaging complex
10
28
2.558077
0.010525
P07305,P16402,P10412,P16104,Q9NPF5,Q8NB78,Q92522,P16403,Q99549,P62805
Localization
GO Cellular component
msigdb_gocc
245,95,190,103,268,10,237,227,153,277
681,1982,1219,2207,245,190,103,95,227,3404,277,2740,2696,900,902,3383,10,237,358,153,2358,268,1970,1367,552,977,2364,2833
0.6644077422188699,-0.18986101163713162,0.27296683220001094,-0.32339579074041863,1.3069742818074888,1.4658276708247233,2.0009706871850725,2.0634452922827657,1.338799977605599,-1.9790084450731824,1.2432393107605846,-0.6937989237284957,-0.6599263948599569,0.5018723958328761,0.5018723958328761,-1.8013419107859299,3.9257537181006645,1.338799977605599,1.0834071043843578,1.6870894061892987,-0.3903896488181674,1.275120777065889,-0.15657014623897816,0.2072660552143123,0.8261633820993779,0.4692696641062204,-0.3903896488181674,-0.761667607945778
3,475
Neurotransmitter transport
11
29
2.54488
0.010932
Q5SQN1,P0DP25,O95721,P50897,O14795,P56545,O75955,P41440,Q06787,O00161,Q9H2J7
Processes and pathways
GO Biological process
msigdb_gobp
543,65,308,351,102,326,480,20,589,555,424
555,2098,102,2100,480,308,988,1770,65,1116,1535,1536,2846,20,2588,351,2339,326,3062,589,1650,1085,1799,543,3122,711,424,1680,2413
0.7938735177908782,-0.25655361902926604,2.0009706871850725,-0.25655361902926604,0.89065247147567,1.1793918752131152,0.4366345847838189,-0.05691626960112453,2.405325005947192,0.33853323249162104,0.07545436686033442,0.07545436686033442,-0.7956643954387234,3.263161715062665,-0.5585523596845848,1.0834071043843578,-0.3903896488181674,1.1474255928962198,-1.0005399910393864,0.7615532030666726,0.009339846996152005,0.3712665741938593,-0.05691626960112453,0.8261633820993779,-1.0691809388636886,0.6644077422188699,0.9871621278015353,0.009339846996152005,-0.42394413865700914
3,475
Tissue ischemia
6
20
2.539744
0.011093
P05067,O15460,O75844,Q9NZ08,P02545,P01889
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
274,162,224,25,432,54
1584,162,1936,224,54,432,2269,274,1939,686,1993,2850,1783,1944,3206,1129,465,25,1319,1928
0.04241468851205189,1.5924222429530126,-0.15657014623897816,1.338799977605599,2.559784134405456,0.9550218762313673,-0.3568736241903287,1.2432393107605846,-0.15657014623897816,0.6644077422188699,-0.18986101163713162,-0.7956643954387234,-0.05691626960112453,-0.15657014623897816,-1.2070036199349412,0.33853323249162104,0.922852047787671,3.1720572250461965,0.24013334861470298,-0.12331590050833183
3,475
Detection of stimulus
8
18
2.535656
0.011224
P0DP25,Q8WTV0,P04439,Q13432,P19022,P30536,P14923,P01889
Processes and pathways
GO Biological process
msigdb_gobp
65,663,535,104,262,772,177,54
798,54,934,535,65,177,262,2687,772,1783,2694,104,1895,1726,1953,663,1416,1865
0.5669816119272515,2.559784134405456,0.4692696641062204,0.8261633820993779,2.405325005947192,1.5291785218097205,1.275120777065889,-0.6599263948599569,0.5994884884196273,-0.05691626960112453,-0.6599263948599569,2.0009706871850725,-0.12331590050833183,-0.023770392974690285,-0.15657014623897816,0.6968204986884444,0.1743647331482899,-0.09009802404997375
3,475
Epistaxis
7
16
2.524041
0.011601
P38435,Q14980,O15460,Q6UN15,P49257,P01889,P10644
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
309,542,162,112,648,54,560
162,54,2374,645,560,1772,1887,309,2424,648,1895,542,112,1802,2867,1974
1.5924222429530126,2.559784134405456,-0.42394413865700914,0.6968204986884444,0.7938735177908782,-0.05691626960112453,-0.12331590050833183,1.1793918752131152,-0.4575373713799266,0.6968204986884444,-0.12331590050833183,0.8261633820993779,1.9696962435077099,-0.05691626960112453,-0.7956643954387234,-0.15657014623897816
3,475
Mitochondrial fusion
8
14
2.517261
0.011827
O95140,Q07812,O60313,Q9Y3D6,Q9Y4W6,Q9NX63,Q9UJZ1,Q9NQG6
Processes and pathways
GO Biological process
msigdb_gobp
244,591,411,52,553,121,364,156
411,244,933,591,2702,1657,662,2990,156,121,364,52,553,1929
0.9871621278015353,1.3069742818074888,0.4692696641062204,0.7615532030666726,-0.6599263948599569,0.009339846996152005,0.6968204986884444,-0.8979084274692133,1.6555599569329296,1.9070724559775802,1.0834071043843578,2.590607268495023,0.8261633820993779,-0.12331590050833183
3,475
Vestibular dysfunction
6
32
2.495194
0.012589
P0DP25,O15460,Q6UN15,P41440,Q9NZ08,P01889
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
65,162,112,20,25,54
3251,1825,1690,162,54,1939,645,2523,65,560,177,2846,1224,2423,1783,1835,510,2424,1888,20,2893,3206,1000,542,1043,112,1802,2867,1012,3150,25,2263
-1.3108557315234917,-0.09009802404997375,-0.023770392974690285,1.5924222429530126,2.559784134405456,-0.15657014623897816,0.6968204986884444,-0.524841194797217,2.405325005947192,0.7938735177908782,1.5291785218097205,-0.7956643954387234,0.27296683220001094,-0.4575373713799266,-0.05691626960112453,-0.09009802404997375,0.8584229744726526,-0.4575373713799266,-0.12331590050833183,3.263161715062665,-0.8297032421061233,-1.2070036199349412,0.4366345847838189,0.8261633820993779,0.4039669561578337,1.9696962435077099,-0.05691626960112453,-0.7956643954387234,0.4366345847838189,-1.1035684565388577,3.1720572250461965,-0.32339579074041863
3,475
Disproportionate short stature
10
27
2.488685
0.012822
O15228,O00116,Q8WVQ1,O75718,Q32P28,Q14696,Q03164,Q15392,Q14739,P10644
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
365,346,77,479,441,148,458,91,250,560
346,365,2462,479,1877,560,2274,1386,1483,2281,458,2666,148,250,1042,2072,91,441,1296,1350,3039,77,707,2498,1358,1863,1753
1.0834071043843578,1.0513545753283584,-0.4911696283708453,0.89065247147567,-0.12331590050833183,0.7938735177908782,-0.3568736241903287,0.1743647331482899,0.10845911446660461,-0.3568736241903287,0.922852047787671,-0.6260946606959044,1.7185927649678452,1.3069742818074888,0.4039669561578337,-0.22318875028858487,2.094645697510917,0.9550218762313673,0.24013334861470298,0.2072660552143123,-0.9662858408639224,2.281339075443853,0.6644077422188699,-0.4911696283708453,0.2072660552143123,-0.09009802404997375,-0.023770392974690285
3,475
Peptidyl lysine trimethylation
7
19
2.48673
0.012892
P51608,P16402,P10412,Q96ST2,P16403,Q5T5X7,P02545
Processes and pathways
GO Biological process
msigdb_gobp
310,95,190,446,227,24,432
1379,1934,840,432,190,95,227,310,458,1083,2777,24,903,3169,2403,2306,446,2034,1749
0.1743647331482899,-0.15657014623897816,0.5344429793834905,0.9550218762313673,1.4658276708247233,2.0634452922827657,1.338799977605599,1.1793918752131152,0.922852047787671,0.3712665741938593,-0.72771255680608,3.1720572250461965,0.5018723958328761,-1.1380011591326509,-0.42394413865700914,-0.3568736241903287,0.9550218762313673,-0.18986101163713162,-0.023770392974690285
3,475
Abnormal epiphyseal ossification
11
17
2.479201
0.013168
Q15738,P38435,P56589,P40855,O00116,Q9UG56,O96011,P08236,O75381,Q14739,P10644
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
955,309,41,940,346,1063,886,275,430,250,560
346,2462,430,886,275,560,309,940,41,250,1042,2072,955,1358,1570,1863,1063
1.0834071043843578,-0.4911696283708453,0.9550218762313673,0.5018723958328761,1.2432393107605846,0.7938735177908782,1.1793918752131152,0.4692696641062204,2.775073997044326,1.3069742818074888,0.4039669561578337,-0.22318875028858487,0.4692696641062204,0.2072660552143123,0.07545436686033442,-0.09009802404997375,0.4039669561578337
3,475
Rnd3 gtpase cycle
6
17
2.470153
0.013506
Q86UP2,P38159,O75976,P15924,Q9Y2U8,Q13464
Processes and pathways
Reactome Pathways
msigdb_reactome
205,74,225,81,258,152
2326,225,3431,81,74,1491,851,152,1400,1085,1289,205,604,1576,269,1109,258
-0.3903896488181674,1.338799977605599,-2.3386618075537435,2.2502835286953093,2.3123708840455612,0.10845911446660461,0.5344429793834905,1.6870894061892987,0.1743647331482899,0.3712665741938593,0.24013334861470298,1.4341117147858753,0.7615532030666726,0.07545436686033442,1.275120777065889,0.3712665741938593,1.3069742818074888
3,475
Primary mitochondrial disease
40
97
2.46823
0.013578
Q9Y2R9,Q70HW3,Q9H0R6,O95169,Q9NYY8,Q00059,P82930,P14927,Q96RP9,O60313,O00483,O75880,P13073,Q8N183,Q9Y2R0,Q6DKK2,P20674,Q9Y3D9,Q8TB37,Q9H845,Q9Y375,Q9P2R7,Q96IX5,Q16795,P52815,Q9Y276,O75879,P22695,P82650,Q9Y2Z9,Q9NWS8,Q99797,P03886,O75306,P09001,O95831,Q5XKP0,Q9P032,O43676,Q07021
Drugs and Diseases
Protein Atlas Disease involvement
protein_atlas_disease_involvement
532,781,672,16,157,415,651,40,830,411,800,291,433,194,67,68,687,475,471,868,79,872,344,597,87,877,338,586,588,94,761,631,349,347,723,109,736,255,613,376
800,2418,613,3343,1071,411,1634,347,1635,841,338,291,16,2372,109,2421,3264,349,2464,1985,1771,723,1477,433,1990,40,938,687,586,1078,2470,2423,1482,1079,1890,997,1487,2058,87,2943,588,651,415,376,597,2348,1955,1137,1800,1898,736,68,1138,781,1609,3170,1093,194,1353,1243,471,1354,965,2029,344,830,3150,631,2824,1514,3015,2609,2647,672,868,1968,1059,761,1209,157,255,2260,872,2615,1682,877,1867,67,532,1323,94,79,2516,2454,475,2147,2265
0.5669816119272515,-0.4575373713799266,0.7292022575003356,-1.554860075681201,0.3712665741938593,0.9871621278015353,0.009339846996152005,1.0834071043843578,0.009339846996152005,0.5344429793834905,1.1154307228188172,1.2113297287229814,3.655839397007132,-0.42394413865700914,1.9696962435077099,-0.4575373713799266,-1.3455675981762987,1.0834071043843578,-0.4911696283708453,-0.18986101163713162,-0.05691626960112453,0.631963801638392,0.10845911446660461,0.9550218762313673,-0.18986101163713162,2.836385499712057,0.4692696641062204,0.6644077422188699,0.7615532030666726,0.3712665741938593,-0.4911696283708453,-0.4575373713799266,0.10845911446660461,0.3712665741938593,-0.12331590050833183,0.4366345847838189,0.10845911446660461,-0.22318875028858487,2.1258216652317476,-0.8637844753937785,0.7615532030666726,0.6968204986884444,0.9871621278015353,1.0513545753283584,0.7615532030666726,-0.3903896488181674,-0.15657014623897816,0.33853323249162104,-0.05691626960112453,-0.12331590050833183,0.631963801638392,2.374363737780149,0.33853323249162104,0.5994884884196273,0.04241468851205189,-1.1380011591326509,0.3712665741938593,1.4658276708247233,0.2072660552143123,0.27296683220001094,0.922852047787671,0.2072660552143123,0.4692696641062204,-0.18986101163713162,1.1154307228188172,0.5669816119272515,-1.1035684565388577,0.7292022575003356,-0.761667607945778,0.10845911446660461,-0.9320754353215098,-0.5585523596845848,-0.5923034159930741,0.6968204986884444,0.5344429793834905,-0.15657014623897816,0.4039669561578337,0.631963801638392,0.3057667222448112,1.6555599569329296,1.3069742818074888,-0.32339579074041863,0.5344429793834905,-0.5585523596845848,0.009339846996152005,0.5344429793834905,-0.09009802404997375,2.405325005947192,0.8584229744726526,0.24013334861470298,2.094645697510917,2.281339075443853,-0.4911696283708453,-0.4575373713799266,0.922852047787671,-0.25655361902926604,-0.32339579074041863
3,475
Nucleosome assembly
9
33
2.466777
0.013634
Q01105,P07305,P16402,P10412,P16104,Q92522,P16403,Q9H7B4,P62805
Processes and pathways
GO Biological process
msigdb_gobp
436,245,95,190,103,237,227,29,277
1072,681,645,245,190,103,95,227,1388,2966,1995,1080,2282,2474,277,436,1342,1549,2979,902,1613,237,2750,968,2356,1739,1623,29,973,1205,1206,1367,498
0.3712665741938593,0.6644077422188699,0.6968204986884444,1.3069742818074888,1.4658276708247233,2.0009706871850725,2.0634452922827657,1.338799977605599,0.1743647331482899,-0.8979084274692133,-0.18986101163713162,0.3712665741938593,-0.3568736241903287,-0.4911696283708453,1.2432393107605846,0.9550218762313673,0.2072660552143123,0.07545436686033442,-0.8979084274692133,0.5018723958328761,0.04241468851205189,1.338799977605599,-0.6937989237284957,0.4692696641062204,-0.3903896488181674,-0.023770392974690285,0.04241468851205189,3.1112169427024057,0.4692696641062204,0.3057667222448112,0.3057667222448112,0.2072660552143123,0.89065247147567
3,475
Organelle membrane fusion
17
35
2.447359
0.014391
Q9BSR8,Q5SQN1,P07355,Q12981,Q9UNK0,O95721,Q9H270,Q9Y3E7,Q9NVJ2,Q9P2R3,P51809,Q8WUH2,O60499,Q86Y82,O00161,Q13190,Q15075
Processes and pathways
GO Biological process
msigdb_gobp
670,543,559,654,334,308,303,679,974,975,618,859,454,700,555,894,489
555,2152,2998,454,1697,1074,1532,308,1701,559,935,1781,2172,2116,618,2000,1650,654,894,2861,489,543,700,2183,1657,859,1614,670,303,974,975,1823,334,1160,679
0.7938735177908782,-0.2899558780062751,-0.9320754353215098,0.922852047787671,-0.023770392974690285,0.3712665741938593,0.07545436686033442,1.1793918752131152,-0.023770392974690285,0.7938735177908782,0.4692696641062204,-0.05691626960112453,-0.2899558780062751,-0.25655361902926604,0.7292022575003356,-0.18986101163713162,0.009339846996152005,0.6968204986884444,0.5018723958328761,-0.7956643954387234,0.89065247147567,0.8261633820993779,0.6644077422188699,-0.2899558780062751,0.009339846996152005,0.5344429793834905,0.04241468851205189,0.6968204986884444,1.2113297287229814,0.4692696641062204,0.4692696641062204,-0.05691626960112453,1.1474255928962198,0.33853323249162104,0.6968204986884444
3,475
Mitochondrial transport
30
92
2.443011
0.014565
O95140,O43772,O60830,Q6NUK1,Q99595,Q9UII2,Q9UJS0,O14737,O43615,P10809,Q9NS69,Q9H270,Q9HAV7,P06576,Q9Y3D6,P56385,O43464,O95817,P36542,Q9UJZ1,Q07812,Q99797,Q5JRX3,O75947,O95831,P48047,P50416,Q9Y512,P55786,Q9NRK6
Processes and pathways
GO Biological process
msigdb_gobp
244,1,3,516,134,136,677,260,273,536,39,303,576,292,52,183,429,558,456,364,591,631,105,348,109,229,113,259,125,527
1166,3251,260,1426,429,273,1,3,1217,1636,348,3234,1381,244,2205,1270,558,109,932,3264,2269,1428,292,2330,1882,536,1477,2581,1329,688,1078,3112,2687,772,3060,456,1707,1281,229,1709,648,3087,2588,113,816,2898,125,1543,183,3090,591,1001,1553,3290,2010,1239,2012,1294,2348,105,516,2702,1804,857,2299,784,3401,1197,1199,3214,1619,1458,134,631,2507,303,576,527,39,2260,1862,2758,2615,136,677,364,877,1526,52,259,2456,1164
0.3057667222448112,-1.3108557315234917,1.275120777065889,0.14142916094516933,0.9550218762313673,1.2432393107605846,5.514987445868287,4.902800840805222,0.27296683220001094,0.009339846996152005,1.0834071043843578,-1.2761913810585277,0.1743647331482899,1.3069742818074888,-0.32339579074041863,0.24013334861470298,0.7938735177908782,1.9696962435077099,0.4692696641062204,-1.3455675981762987,-0.3568736241903287,0.14142916094516933,1.2113297287229814,-0.3903896488181674,-0.12331590050833183,0.8261633820993779,0.10845911446660461,-0.5585523596845848,0.2072660552143123,0.6644077422188699,0.3712665741938593,-1.0691809388636886,-0.6599263948599569,0.5994884884196273,-1.0005399910393864,0.922852047787671,-0.023770392974690285,0.24013334861470298,1.338799977605599,-0.023770392974690285,0.6968204986884444,-1.0348382379290142,-0.5585523596845848,1.93839687467804,0.5669816119272515,-0.8297032421061233,1.8757228615346935,0.07545436686033442,1.4975165585697592,-1.0348382379290142,0.7615532030666726,0.4366345847838189,0.07545436686033442,-1.4151355272862594,-0.18986101163713162,0.27296683220001094,-0.18986101163713162,0.24013334861470298,-0.3903896488181674,2.0009706871850725,0.8584229744726526,-0.6599263948599569,-0.05691626960112453,0.5344429793834905,-0.3568736241903287,0.5994884884196273,-1.9433641305204705,0.3057667222448112,0.3057667222448112,-1.2070036199349412,0.04241468851205189,0.14142916094516933,1.8129476360755272,0.7292022575003356,-0.4911696283708453,1.2113297287229814,0.7938735177908782,0.8584229744726526,2.8670084338016997,-0.32339579074041863,-0.09009802404997375,-0.6937989237284957,-0.5585523596845848,1.8129476360755272,0.6968204986884444,1.0834071043843578,0.5344429793834905,0.10845911446660461,2.590607268495023,1.3069742818074888,-0.4575373713799266,0.33853323249162104
3,475
Mrna splice site selection
9
21
2.423949
0.015353
Q8WXF0,O95391,O75494,Q07955,Q13242,Q13247,Q96MU7,Q15459,O75475
Processes and pathways
GO Biological process
msigdb_gobp
96,506,387,210,462,513,522,439,123
123,387,1875,506,724,210,1133,1496,462,1084,513,2347,439,596,1656,96,522,1969,1753,1259,3360
1.8757228615346935,1.0192729716930538,-0.12331590050833183,0.8584229744726526,0.631963801638392,1.402368545245139,0.33853323249162104,0.10845911446660461,0.922852047787671,0.3712665741938593,0.8584229744726526,-0.3903896488181674,0.9550218762313673,0.7615532030666726,0.009339846996152005,2.0634452922827657,0.8584229744726526,-0.15657014623897816,-0.023770392974690285,0.27296683220001094,-1.6250237525158988
3,475
Processing of smdt1
6
11
2.422407
0.015418
Q9BPX6,P35232,Q8IYU8,Q99623,Q9UJZ1,Q96TA2
Processes and pathways
Reactome Pathways
msigdb_reactome
240,455,179,319,364,524
1636,455,1001,179,1007,1197,524,319,240,364,553
0.009339846996152005,0.922852047787671,0.4366345847838189,1.5291785218097205,0.4366345847838189,0.3057667222448112,0.8584229744726526,1.1793918752131152,1.338799977605599,1.0834071043843578,0.8261633820993779
3,475
Exocytic process
8
21
2.418869
0.015569
Q5SQN1,O95721,Q9H270,O14795,P56545,Q7Z6M1,P07948,O00161
Processes and pathways
GO Biological process
msigdb_gobp
543,308,303,102,326,442,120,555
555,2098,102,2763,308,120,1535,2116,618,2339,326,2000,948,1650,1085,543,442,858,303,1680,2264
0.7938735177908782,-0.25655361902926604,2.0009706871850725,-0.72771255680608,1.1793918752131152,1.9070724559775802,0.07545436686033442,-0.25655361902926604,0.7292022575003356,-0.3903896488181674,1.1474255928962198,-0.18986101163713162,0.4692696641062204,0.009339846996152005,0.3712665741938593,0.8261633820993779,0.9550218762313673,0.5344429793834905,1.2113297287229814,0.009339846996152005,-0.32339579074041863
3,475
Apoptotic execution phase
11
35
2.409383
0.01598
P07305,P16402,P10412,P08670,P16403,P15924,Q07157,P20700,Q13464,Q16625,P02545
Processes and pathways
Reactome Pathways
msigdb_reactome
245,95,190,71,227,81,459,374,152,154,432
2958,1111,432,245,71,2579,190,81,95,227,374,1033,2966,1783,1643,2055,2894,816,1284,1839,2694,1288,459,1718,152,594,655,2537,954,154,1058,1256,874,2923,499
-0.8979084274692133,0.33853323249162104,0.9550218762313673,1.3069742818074888,2.343379067489768,-0.5585523596845848,1.4658276708247233,2.2502835286953093,2.0634452922827657,1.338799977605599,1.0513545753283584,0.4039669561578337,-0.8979084274692133,-0.05691626960112453,0.009339846996152005,-0.22318875028858487,-0.8297032421061233,0.5669816119272515,0.24013334861470298,-0.09009802404997375,-0.6599263948599569,0.24013334861470298,0.922852047787671,-0.023770392974690285,1.6870894061892987,0.7615532030666726,0.6968204986884444,-0.524841194797217,0.4692696641062204,1.6555599569329296,0.4039669561578337,0.27296683220001094,0.5344429793834905,-0.8297032421061233,0.89065247147567
3,475
Respirasome
22
47
2.40422
0.016207
O43920,O95169,O95182,P14927,O43674,Q96CU9,O00483,P13073,Q6DKK2,P20674,O14548,P10606,Q9Y375,Q9UDW1,Q16795,Q9Y276,P22695,O75489,P03886,O75306,O95168,O43676
Localization
GO Cellular component
msigdb_gocc
504,16,885,40,410,965,800,433,68,687,188,809,79,873,597,877,586,841,349,347,721,613
800,188,2418,410,613,3343,504,1634,347,1635,841,721,16,885,2372,2159,2421,349,2464,1771,809,433,1989,1990,40,1703,938,687,1224,586,2470,2423,3114,1487,1838,1793,2181,597,68,3170,965,1209,2260,873,877,79,2265
0.5669816119272515,1.4658276708247233,-0.4575373713799266,0.9871621278015353,0.7292022575003356,-1.554860075681201,0.8584229744726526,0.009339846996152005,1.0834071043843578,0.009339846996152005,0.5344429793834905,0.631963801638392,3.655839397007132,0.5018723958328761,-0.42394413865700914,-0.2899558780062751,-0.4575373713799266,1.0834071043843578,-0.4911696283708453,-0.05691626960112453,0.5669816119272515,0.9550218762313673,-0.18986101163713162,-0.18986101163713162,2.836385499712057,-0.023770392974690285,0.4692696641062204,0.6644077422188699,0.27296683220001094,0.7615532030666726,-0.4911696283708453,-0.4575373713799266,-1.0691809388636886,0.10845911446660461,-0.09009802404997375,-0.05691626960112453,-0.2899558780062751,0.7615532030666726,2.374363737780149,-1.1380011591326509,0.4692696641062204,0.3057667222448112,-0.32339579074041863,0.5344429793834905,0.5344429793834905,2.281339075443853,-0.32339579074041863
3,475
EF-Hand 1, calcium-binding site [IPR018247]
14
40
2.403676
0.016231
Q9UBC2,P0DP25,Q15293,Q96AY3,Q9NZM3,Q6NUK1,Q13813,Q96D71,Q9BPX6,Q14257,O95302,Q9Y680,O43852,Q9BRK5
Sequence
InterPro Binding site
interpro_binding_site
529,65,234,400,306,516,594,239,240,233,44,289,146,197
1694,146,1073,806,1327,44,1474,65,1772,3284,1176,1774,1833,2584,2967,617,2168,1391,1287,2481,1491,594,233,2778,234,516,1804,857,400,239,240,197,1361,3018,1748,306,529,3380,2039,289
-0.023770392974690285,1.7185927649678452,0.3712665741938593,0.5669816119272515,0.2072660552143123,2.7443852320603073,0.10845911446660461,2.405325005947192,-0.05691626960112453,-1.4151355272862594,0.3057667222448112,-0.05691626960112453,-0.09009802404997375,-0.5585523596845848,-0.8979084274692133,0.7292022575003356,-0.2899558780062751,0.1743647331482899,0.24013334861470298,-0.4911696283708453,0.10845911446660461,0.7615532030666726,1.338799977605599,-0.72771255680608,1.338799977605599,0.8584229744726526,-0.05691626960112453,0.5344429793834905,1.0192729716930538,1.338799977605599,1.338799977605599,1.4658276708247233,0.2072660552143123,-0.9320754353215098,-0.023770392974690285,1.2113297287229814,0.8584229744726526,-1.765972455067393,-0.18986101163713162,1.2432393107605846
3,475
Decreased activity of mitochondrial complex iv
9
14
2.397312
0.016516
Q9Y2R0,P20674,Q9Y3D9,Q96RP9,Q70HW3,Q9H0R6,P82663,P52815,P13073
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
67,687,475,830,781,672,294,87,433
800,433,687,1079,1890,87,2943,294,1955,781,830,672,67,475
0.5669816119272515,0.9550218762313673,0.6644077422188699,0.3712665741938593,-0.12331590050833183,2.1258216652317476,-0.8637844753937785,1.2113297287229814,-0.15657014623897816,0.5994884884196273,0.5669816119272515,0.6968204986884444,2.405325005947192,0.922852047787671
3,475
Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps
10
18
2.391863
0.016763
P05067,Q15293,Q5JRA6,Q9BTY2,Q86UP2,P14625,P19022,Q13217,O43852,O76024
Processes and pathways
Reactome Pathways
msigdb_reactome
274,234,822,831,205,323,262,461,146,431
1825,146,431,274,2375,1176,323,262,2161,2481,851,461,1722,234,822,205,2819,831
-0.09009802404997375,1.7185927649678452,0.9550218762313673,1.2432393107605846,-0.42394413865700914,0.3057667222448112,1.1474255928962198,1.275120777065889,-0.2899558780062751,-0.4911696283708453,0.5344429793834905,0.922852047787671,-0.023770392974690285,1.338799977605599,0.5669816119272515,1.4341117147858753,-0.761667607945778,0.5669816119272515
3,475
Vesicle mediated transport in synapse
10
38
2.389657
0.016864
Q5SQN1,P0DP25,O95721,Q9NZM3,O14795,P56545,P19022,P51790,Q13464,O00161
Processes and pathways
GO Biological process
msigdb_gobp
543,65,308,306,102,326,262,50,152,555
555,2459,2927,102,2100,2200,308,1770,65,1116,262,1535,1536,1429,1783,2588,2224,50,2339,326,2000,3062,589,1650,152,1400,1085,1799,543,2438,2443,1619,2553,306,1680,1024,1321,2413
0.7938735177908782,-0.4911696283708453,-0.8637844753937785,2.0009706871850725,-0.25655361902926604,-0.32339579074041863,1.1793918752131152,-0.05691626960112453,2.405325005947192,0.33853323249162104,1.275120777065889,0.07545436686033442,0.07545436686033442,0.14142916094516933,-0.05691626960112453,-0.5585523596845848,-0.32339579074041863,2.621407751431034,-0.3903896488181674,1.1474255928962198,-0.18986101163713162,-1.0005399910393864,0.7615532030666726,0.009339846996152005,1.6870894061892987,0.1743647331482899,0.3712665741938593,-0.05691626960112453,0.8261633820993779,-0.4575373713799266,-0.4575373713799266,0.04241468851205189,-0.524841194797217,1.2113297287229814,0.009339846996152005,0.4366345847838189,0.24013334861470298,-0.42394413865700914
3,475
Microbody
17
56
2.386983
0.016987
O15228,Q8N4Q0,P09110,Q9BY49,P48735,P08670,P56589,O15254,O75874,O00116,O75521,Q9Y3D6,Q15067,P34913,Q9NR77,O75381,Q9NQG6
Localization
GO Cellular component
msigdb_gocc
365,236,246,167,5,71,41,169,75,346,388,52,315,23,118,430,156
346,1111,477,365,169,534,929,430,388,75,1031,886,644,71,246,3027,2467,847,1642,3183,3142,1782,23,1180,1482,940,5,2173,1489,1785,2473,41,852,3464,2288,3333,315,2908,658,738,904,1092,2245,236,2078,862,2710,2874,2504,167,156,118,3077,925,52,3415
1.0834071043843578,0.33853323249162104,0.89065247147567,1.0513545753283584,1.5608137029341247,0.8261633820993779,0.4692696641062204,0.9550218762313673,1.0192729716930538,2.281339075443853,0.4039669561578337,0.5018723958328761,0.6968204986884444,2.343379067489768,1.3069742818074888,-0.9662858408639224,-0.4911696283708453,0.5344429793834905,0.009339846996152005,-1.1724794204274362,-1.1035684565388577,-0.05691626960112453,3.1720572250461965,0.3057667222448112,0.10845911446660461,0.4692696641062204,4.667687825369334,-0.2899558780062751,0.10845911446660461,-0.05691626960112453,-0.4911696283708453,2.775073997044326,0.5344429793834905,-3.6871244846496367,-0.3568736241903287,-1.5198542631539218,1.1793918752131152,-0.8297032421061233,0.6968204986884444,0.631963801638392,0.5018723958328761,0.3712665741938593,-0.32339579074041863,1.338799977605599,-0.22318875028858487,0.5344429793834905,-0.6599263948599569,-0.7956643954387234,-0.4911696283708453,1.5924222429530126,1.6555599569329296,1.93839687467804,-1.0005399910393864,0.5018723958328761,2.590607268495023,-2.050467446495352
3,475
Abnormal enchondral ossification
17
31
2.384437
0.017105
Q15738,P38435,Q14807,P36776,P56589,P40855,O00116,Q8WVQ1,O96011,Q9UG56,P08236,Q5F1R6,O96028,Q9Y619,O75381,Q14739,P10644
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
955,309,1042,690,41,940,346,77,886,1063,275,1089,182,187,430,250,560
346,2462,430,1327,886,182,275,560,2582,690,309,940,41,1339,1601,2775,250,1042,2072,955,1089,3039,77,2498,1358,1570,1104,1863,1063,1974,187
1.0834071043843578,-0.4911696283708453,0.9550218762313673,0.2072660552143123,0.5018723958328761,1.4975165585697592,1.2432393107605846,0.7938735177908782,-0.5585523596845848,0.6644077422188699,1.1793918752131152,0.4692696641062204,2.775073997044326,0.2072660552143123,0.04241468851205189,-0.72771255680608,1.3069742818074888,0.4039669561578337,-0.22318875028858487,0.4692696641062204,0.3712665741938593,-0.9662858408639224,2.281339075443853,-0.4911696283708453,0.2072660552143123,0.07545436686033442,0.3712665741938593,-0.09009802404997375,0.4039669561578337,-0.15657014623897816,1.4975165585697592
3,475
Mitochondrial translation
27
49
2.382865
0.017178
Q9Y2R9,Q9H0R6,O95182,Q14197,Q9NYY8,Q96EY7,P82930,Q8NC60,P82673,Q96RP9,Q5T653,Q9Y2R0,Q9NX20,P82912,P42704,Q9HD33,Q16540,Q92552,O75879,Q9BZE1,Q9NWS8,Q5JTZ9,Q567V2,Q07021,Q5T160,P49411,P34897
Processes and pathways
GO Biological process
msigdb_gobp
532,672,885,774,157,545,651,962,538,830,1090,67,474,694,1079,870,82,746,338,1016,761,1137,853,376,251,997,994
338,885,994,2629,1079,1890,997,538,694,1231,651,376,774,2346,82,853,1955,1137,251,1090,1404,1899,1609,962,746,545,830,3040,1514,2647,1016,672,1968,870,1675,1363,2994,761,474,157,1682,1867,67,1162,532,1323,2516,2454,1213
1.1154307228188172,0.5018723958328761,0.4366345847838189,-0.5923034159930741,0.3712665741938593,-0.12331590050833183,0.4366345847838189,0.8261633820993779,0.6644077422188699,0.27296683220001094,0.6968204986884444,1.0513545753283584,0.5994884884196273,-0.3903896488181674,2.2502835286953093,0.5344429793834905,-0.15657014623897816,0.33853323249162104,1.3069742818074888,0.3712665741938593,0.1743647331482899,-0.12331590050833183,0.04241468851205189,0.4692696641062204,0.631963801638392,0.8261633820993779,0.5669816119272515,-0.9662858408639224,0.10845911446660461,-0.5923034159930741,0.4366345847838189,0.6968204986884444,-0.15657014623897816,0.5344429793834905,0.009339846996152005,0.2072660552143123,-0.8979084274692133,0.631963801638392,0.922852047787671,1.6555599569329296,0.009339846996152005,-0.09009802404997375,2.405325005947192,0.33853323249162104,0.8584229744726526,0.24013334861470298,-0.4911696283708453,-0.4575373713799266,0.3057667222448112
3,475
Protein dna complex
14
61
2.381731
0.017231
Q96L91,Q9NYB0,P07305,Q00403,P16402,P10412,P16104,Q9NPF5,Q8NB78,Q92522,P16403,P14923,Q99549,P62805
Localization
GO Cellular component
msigdb_gocc
358,402,245,131,95,190,103,268,10,237,227,177,153,277
681,804,1219,2207,645,245,2580,2845,190,1077,3391,1587,2655,177,3137,103,95,227,2106,1883,2165,2528,507,1178,1591,1994,1995,1783,2657,2221,1997,2852,2282,1999,277,2971,131,2667,1950,3189,1344,1555,900,902,10,237,358,153,1811,2135,2558,268,402,1367,2509,552,977,612,2364,406,2833
0.6644077422188699,0.5669816119272515,0.27296683220001094,-0.32339579074041863,0.6968204986884444,1.3069742818074888,-0.5585523596845848,-0.7956643954387234,1.4658276708247233,0.3712665741938593,-1.8722430913337662,0.04241468851205189,-0.6260946606959044,1.5291785218097205,-1.1035684565388577,2.0009706871850725,2.0634452922827657,1.338799977605599,-0.25655361902926604,-0.12331590050833183,-0.2899558780062751,-0.524841194797217,0.8584229744726526,0.3057667222448112,0.04241468851205189,-0.18986101163713162,-0.18986101163713162,-0.05691626960112453,-0.6260946606959044,-0.32339579074041863,-0.18986101163713162,-0.7956643954387234,-0.3568736241903287,-0.18986101163713162,1.2432393107605846,-0.8979084274692133,1.8129476360755272,-0.6260946606959044,-0.15657014623897816,-1.1724794204274362,0.2072660552143123,0.07545436686033442,0.5018723958328761,0.5018723958328761,3.9257537181006645,1.338799977605599,1.0834071043843578,1.6870894061892987,-0.05691626960112453,-0.25655361902926604,-0.524841194797217,1.275120777065889,1.0192729716930538,0.2072660552143123,-0.4911696283708453,0.8261633820993779,0.4692696641062204,0.7615532030666726,-0.3903896488181674,1.0192729716930538,-0.761667607945778
3,475
Epiphyseal stippling
9
13
2.378731
0.017372
Q15738,P38435,P56589,O00116,O96011,P08236,O75381,Q14739,P10644
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
955,309,41,346,886,275,430,250,560
346,2462,430,886,275,560,309,940,41,250,2072,955,1863
1.0834071043843578,-0.4911696283708453,0.9550218762313673,0.5018723958328761,1.2432393107605846,0.7938735177908782,1.1793918752131152,0.4692696641062204,2.775073997044326,1.3069742818074888,-0.22318875028858487,0.4692696641062204,-0.09009802404997375
3,475
Mitotic chromosome
14
38
2.375282
0.017536
Q9BYG3,Q76FK4,Q13601,P19338,Q99848,Q5QJE6,Q96B26,Q9NYH9,Q9UMY1,Q9Y3B9,Q6PK04,O00566,Q9H6F5,O75683
Localization
Protein Atlas Subcellular
protein_atlas_subcellular_location_all
497,601,541,171,447,466,749,450,322,452,86,476,425,368
1585,476,2683,368,1767,171,941,1538,1338,2006,541,1442,897,1603,1500,466,86,601,3069,1193,744,2301,1456,749,447,1414,1963,497,425,1521,1626,1060,1210,450,322,3047,452,1025
0.04241468851205189,0.89065247147567,-0.6599263948599569,1.0513545753283584,-0.05691626960112453,1.5608137029341247,0.4692696641062204,0.07545436686033442,0.2072660552143123,-0.18986101163713162,0.8261633820993779,0.14142916094516933,0.5018723958328761,0.04241468851205189,0.10845911446660461,0.922852047787671,2.1569733146226153,0.7615532030666726,-1.0005399910393864,0.3057667222448112,0.631963801638392,-0.3568736241903287,0.14142916094516933,0.631963801638392,0.9550218762313673,0.1743647331482899,-0.15657014623897816,0.89065247147567,0.9871621278015353,0.10845911446660461,0.04241468851205189,0.4039669561578337,0.3057667222448112,0.9550218762313673,1.1793918752131152,-0.9662858408639224,0.9550218762313673,0.4366345847838189
3,475
SNARE protein
7
13
2.363374
0.018109
Q5SQN1,O95721,Q9UNK0,P51809,O60499,Q86Y82,O00161
Functions
Panther Protein class
panther_protein_class
543,308,334,618,454,700,555
555,2152,454,1532,308,618,1650,894,543,700,1677,1318,334
0.7938735177908782,-0.2899558780062751,0.922852047787671,0.07545436686033442,1.1793918752131152,0.7292022575003356,0.009339846996152005,0.5018723958328761,0.8261633820993779,0.6644077422188699,0.009339846996152005,0.24013334861470298,1.1474255928962198
3,475
Regulation of dna recombination
16
51
2.344266
0.019065
Q96L91,Q9NYB0,P07305,P16402,P35637,P10412,Q96B01,Q9NPF5,Q92522,Q7Z3K3,Q7Z4V5,P16403,Q86V81,O96028,Q9NY27,Q9NRR5
Processes and pathways
GO Biological process
msigdb_gobp
358,402,245,95,191,190,473,268,237,492,175,227,211,182,426,199
1424,1828,1219,2207,182,933,245,2580,190,3137,95,227,1776,2162,191,2169,1647,1945,1284,2897,2770,2002,2006,1555,696,823,2815,1505,1190,492,175,211,237,1097,473,966,3098,358,1014,2822,2828,268,2877,199,426,402,552,1865,977,2364,2833
0.14142916094516933,-0.09009802404997375,0.27296683220001094,-0.32339579074041863,1.4975165585697592,0.4692696641062204,1.3069742818074888,-0.5585523596845848,1.4658276708247233,-1.1035684565388577,2.0634452922827657,1.338799977605599,-0.05691626960112453,-0.2899558780062751,1.4658276708247233,-0.2899558780062751,0.009339846996152005,-0.15657014623897816,0.24013334861470298,-0.8297032421061233,-0.72771255680608,-0.18986101163713162,-0.18986101163713162,0.07545436686033442,0.6644077422188699,0.5669816119272515,-0.761667607945778,0.10845911446660461,0.3057667222448112,0.89065247147567,1.5608137029341247,1.402368545245139,1.338799977605599,0.3712665741938593,0.922852047787671,0.4692696641062204,-1.0348382379290142,1.0834071043843578,0.4366345847838189,-0.761667607945778,-0.761667607945778,1.275120777065889,-0.7956643954387234,1.4658276708247233,0.9871621278015353,1.0192729716930538,0.8261633820993779,-0.09009802404997375,0.4692696641062204,-0.3903896488181674,-0.761667607945778
3,475
Rhof gtpase cycle
7
17
2.343131
0.019123
Q9Y4F1,Q8TAA9,P42167,P80723,P20700,O00161,Q07960
Processes and pathways
Reactome Pathways
msigdb_reactome
502,604,691,48,374,555,184
555,1531,1772,374,1836,691,2689,2172,48,1233,184,1045,604,1573,1463,795,502
0.7938735177908782,0.07545436686033442,-0.05691626960112453,1.0513545753283584,-0.09009802404997375,0.6644077422188699,-0.6599263948599569,-0.2899558780062751,2.713674325681347,0.27296683220001094,1.4975165585697592,0.4039669561578337,0.7615532030666726,0.07545436686033442,0.14142916094516933,0.5994884884196273,0.89065247147567
3,475
Transport of the slbp dependant mature mrna
16
31
2.341537
0.019205
P57740,P49790,Q9UKX7,Q99567,Q8N1F7,Q7Z3B4,O15504,Q86V81,Q8WUM0,P12270,P35658,P37198,Q9UBU9,Q9BVL2,Q8TEM1,Q9BTX1
Processes and pathways
Reactome Pathways
msigdb_reactome
650,814,1022,667,906,740,583,211,1008,771,891,392,1062,116,1146,422
583,1765,1880,771,891,392,814,1122,2117,1285,650,2771,1398,1843,2292,740,211,906,1806,1903,1146,1008,1661,2134,667,422,116,1621,1420,1062,1022
0.7615532030666726,-0.05691626960112453,-0.12331590050833183,0.5994884884196273,0.5018723958328761,1.0192729716930538,0.5669816119272515,0.33853323249162104,-0.25655361902926604,0.24013334861470298,0.6968204986884444,-0.72771255680608,0.1743647331482899,-0.09009802404997375,-0.3568736241903287,0.631963801638392,1.402368545245139,0.5018723958328761,-0.05691626960112453,-0.12331590050833183,0.33853323249162104,0.4366345847838189,0.009339846996152005,-0.25655361902926604,0.6968204986884444,0.9871621278015353,1.93839687467804,0.04241468851205189,0.1743647331482899,0.4039669561578337,0.4366345847838189
3,475
Calmodulin
7
15
2.337546
0.019411
P0DP25,Q15293,Q9BPX6,Q14257,Q8IYU8,O43852,Q9BRK5
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
65,234,240,233,179,146,197
146,65,2967,617,3208,1287,2481,233,234,2640,419,179,1956,240,197
1.7185927649678452,2.405325005947192,-0.8979084274692133,0.7292022575003356,-1.2070036199349412,0.24013334861470298,-0.4911696283708453,1.338799977605599,1.338799977605599,-0.5923034159930741,0.9871621278015353,1.5291785218097205,-0.15657014623897816,1.338799977605599,1.4658276708247233
3,475
Intracellular calcium-sensing protein
7
15
2.337546
0.019411
P0DP25,Q15293,Q9BPX6,Q14257,Q8IYU8,O43852,Q9BRK5
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
65,234,240,233,179,146,197
146,65,2967,617,3208,1287,2481,233,234,2640,419,179,1956,240,197
1.7185927649678452,2.405325005947192,-0.8979084274692133,0.7292022575003356,-1.2070036199349412,0.24013334861470298,-0.4911696283708453,1.338799977605599,1.338799977605599,-0.5923034159930741,0.9871621278015353,1.5291785218097205,-0.15657014623897816,1.338799977605599,1.4658276708247233
3,475
Transport of mature mrnas derived from intronless transcripts
19
37
2.334694
0.019559
Q99567,Q8N1F7,P12270,P35658,P37198,Q9UBU9,Q9BTX1,P57740,Q92797,P49790,Q86V81,Q8WUM0,Q8TEM1,O15504,Q9UKX7,Q7Z3B4,Q6UN15,Q9BVL2,Q9P2I0
Processes and pathways
Reactome Pathways
msigdb_reactome
667,906,771,891,392,1062,422,650,1096,814,211,1008,1146,583,1022,740,112,116,921
583,1765,1880,771,891,392,814,1122,2117,1285,650,2771,1398,1716,1843,2292,112,740,211,906,1806,1903,1146,1008,1661,1096,2134,667,422,116,1621,2677,1420,921,1062,1369,1022
0.7615532030666726,-0.05691626960112453,-0.12331590050833183,0.5994884884196273,0.5018723958328761,1.0192729716930538,0.5669816119272515,0.33853323249162104,-0.25655361902926604,0.24013334861470298,0.6968204986884444,-0.72771255680608,0.1743647331482899,-0.023770392974690285,-0.09009802404997375,-0.3568736241903287,1.9696962435077099,0.631963801638392,1.402368545245139,0.5018723958328761,-0.05691626960112453,-0.12331590050833183,0.33853323249162104,0.4366345847838189,0.009339846996152005,0.3712665741938593,-0.25655361902926604,0.6968204986884444,0.9871621278015353,1.93839687467804,0.04241468851205189,-0.6260946606959044,0.1743647331482899,0.5018723958328761,0.4039669561578337,0.2072660552143123,0.4366345847838189
3,475
Predicted secreted proteins
8
51
2.331959
0.019703
Q9H6E4,Q8WUJ1,P51858,Q15165,Q9UMX5,Q9NZ08,Q9HB40,P43490
Functions
Protein Atlas Protein class
protein_atlas_protein_class
99,4,9,51,22,25,30,28
1761,100,479,370,933,1701,274,2686,559,2579,3461,2467,1277,1386,2966,993,28,9,2692,2769,3374,1128,1287,2233,2178,2481,376,1495,2636,1236,2595,51,2984,2870,2601,4,860,2818,3338,707,669,831,3445,3172,99,401,30,25,637,22,1928
-0.05691626960112453,2.032220329290794,0.89065247147567,1.0513545753283584,0.4692696641062204,-0.023770392974690285,1.2432393107605846,-0.6599263948599569,0.7938735177908782,-0.5585523596845848,-3.5716063497331767,-0.4911696283708453,0.24013334861470298,0.1743647331482899,-0.8979084274692133,0.4366345847838189,3.1112169427024057,3.9257537181006645,-0.6599263948599569,-0.72771255680608,-1.7306564073668487,0.33853323249162104,0.24013334861470298,-0.32339579074041863,-0.2899558780062751,-0.4911696283708453,1.0513545753283584,0.10845911446660461,-0.5923034159930741,0.27296683220001094,-0.5585523596845848,2.621407751431034,-0.8979084274692133,-0.7956643954387234,-0.5585523596845848,4.814759722518884,0.5344429793834905,-0.761667607945778,-1.5198542631539218,0.6644077422188699,0.6968204986884444,0.5669816119272515,-2.5574276464493524,-1.1380011591326509,2.0634452922827657,1.0192729716930538,3.1112169427024057,3.1720572250461965,0.7292022575003356,3.2328142246811313,-0.12331590050833183
3,475
Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen
7
34
2.322211
0.020222
O15460,Q8NB78,Q6UW02,Q14534,Q16850,Q9Y2Z9,P30519
Functions
GO Molecular function
msigdb_gomf
162,10,397,327,328,94,62
2417,1324,1693,162,1828,1761,1763,1829,585,986,2375,646,990,2047,1178,62,2808,1130,1082,327,2239,328,441,1607,397,1563,1140,2869,10,2646,3171,1422,1685,94
-0.4575373713799266,0.2072660552143123,-0.023770392974690285,1.5924222429530126,-0.09009802404997375,-0.05691626960112453,-0.05691626960112453,-0.09009802404997375,0.7615532030666726,0.4366345847838189,-0.42394413865700914,0.6968204986884444,0.4366345847838189,-0.22318875028858487,0.3057667222448112,2.4362629820604664,-0.761667607945778,0.33853323249162104,0.3712665741938593,1.1474255928962198,-0.32339579074041863,1.1474255928962198,0.9550218762313673,0.04241468851205189,1.0192729716930538,0.07545436686033442,0.33853323249162104,-0.7956643954387234,3.9257537181006645,-0.5923034159930741,-1.1380011591326509,0.1743647331482899,0.009339846996152005,2.094645697510917
3,475
Respiratory electron transport
25
57
2.319405
0.020373
O43920,O95169,P14927,O43674,O00483,O75880,P13073,Q8N183,P20674,O14548,P10606,Q8TB37,Q9H845,Q9Y375,Q9UDW1,Q16795,P22695,Q12931,Q9BQ95,P03886,O75306,O95168,Q9P032,O43676,Q16134
Processes and pathways
Reactome Pathways
msigdb_reactome
504,16,40,410,800,291,433,194,687,188,809,471,868,79,873,597,586,592,241,349,347,721,255,613,735
800,188,2418,410,613,3343,1071,504,1634,347,1635,841,291,721,16,885,2372,2159,2421,349,2464,1771,809,433,2273,1990,40,1703,938,687,1224,586,2470,2423,3114,1118,1079,1487,1838,592,735,2181,597,3170,194,3401,471,241,3015,868,1059,1209,255,2260,873,79,2265
0.5669816119272515,1.4658276708247233,-0.4575373713799266,0.9871621278015353,0.7292022575003356,-1.554860075681201,0.3712665741938593,0.8584229744726526,0.009339846996152005,1.0834071043843578,0.009339846996152005,0.5344429793834905,1.2113297287229814,0.631963801638392,3.655839397007132,0.5018723958328761,-0.42394413865700914,-0.2899558780062751,-0.4575373713799266,1.0834071043843578,-0.4911696283708453,-0.05691626960112453,0.5669816119272515,0.9550218762313673,-0.3568736241903287,-0.18986101163713162,2.836385499712057,-0.023770392974690285,0.4692696641062204,0.6644077422188699,0.27296683220001094,0.7615532030666726,-0.4911696283708453,-0.4575373713799266,-1.0691809388636886,0.33853323249162104,0.3712665741938593,0.10845911446660461,-0.09009802404997375,0.7615532030666726,0.631963801638392,-0.2899558780062751,0.7615532030666726,-1.1380011591326509,1.4658276708247233,-1.9433641305204705,0.922852047787671,1.338799977605599,-0.9320754353215098,0.5344429793834905,0.4039669561578337,0.3057667222448112,1.3069742818074888,-0.32339579074041863,0.5344429793834905,2.281339075443853,-0.32339579074041863
3,475
Organic acid transmembrane transporter activity
15
22
2.315327
0.020595
Q15758,Q96NB2,P08183,O14745,Q9Y289,P30825,Q9UJS0,O75746,P41440,Q6P1M0,Q02978,Q9Y619,Q9H2J7,O15439,P33527
Functions
GO Molecular function
msigdb_gomf
956,495,8,719,836,509,677,806,20,739,1000,187,424,928,587
719,928,806,1876,8,1032,509,587,20,1946,2901,1000,956,739,495,3196,424,1418,2615,677,836,187
0.631963801638392,0.4692696641062204,0.5669816119272515,-0.12331590050833183,3.9556492376216754,0.4039669561578337,0.8584229744726526,0.7615532030666726,3.263161715062665,-0.15657014623897816,-0.8297032421061233,0.4366345847838189,0.4692696641062204,0.631963801638392,0.89065247147567,-1.1724794204274362,0.9871621278015353,0.1743647331482899,-0.5585523596845848,0.6968204986884444,0.5669816119272515,1.4975165585697592
3,475
Calcium-binding protein
7
19
2.310138
0.020881
P0DP25,Q15293,Q9BPX6,Q14257,Q8IYU8,O43852,Q9BRK5
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
65,234,240,233,179,146,197
146,65,1993,2967,617,1036,3208,1287,2481,233,234,2640,419,179,1956,912,240,197,1374
1.7185927649678452,2.405325005947192,-0.18986101163713162,-0.8979084274692133,0.7292022575003356,0.4039669561578337,-1.2070036199349412,0.24013334861470298,-0.4911696283708453,1.338799977605599,1.338799977605599,-0.5923034159930741,0.9871621278015353,1.5291785218097205,-0.15657014623897816,0.5018723958328761,1.338799977605599,1.4658276708247233,0.2072660552143123
3,475
Fatty acid metabolism
7
29
2.304357
0.021203
P09110,Q16836,O15254,P50416,P11310,Q15067,P30837
Processes and pathways
KEGG Pathways
msigdb_kegg
246,165,169,113,89,315,63
169,929,388,1031,987,246,89,3082,616,1329,1225,1179,63,1782,2730,1181,1593,1707,2222,813,3187,113,2173,1597,852,315,165,1012,1742
1.5608137029341247,0.4692696641062204,1.0192729716930538,0.4039669561578337,0.4366345847838189,1.3069742818074888,2.094645697510917,-1.0348382379290142,0.7292022575003356,0.2072660552143123,0.27296683220001094,0.3057667222448112,2.4362629820604664,-0.05691626960112453,-0.6937989237284957,0.3057667222448112,0.04241468851205189,-0.023770392974690285,-0.32339579074041863,0.5669816119272515,-1.1724794204274362,1.93839687467804,-0.2899558780062751,0.04241468851205189,0.5344429793834905,1.1793918752131152,1.5924222429530126,0.4366345847838189,-0.023770392974690285
3,475
Lower limb amyotrophy
7
22
2.304198
0.021212
O95140,Q92734,O00400,Q9NVI7,Q9NR77,P04792,P02545
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
244,238,409,449,118,119,432
409,2103,244,432,119,1272,1942,2276,1893,2008,1498,733,1044,1735,3096,238,2756,525,118,449,1755,1165
0.9871621278015353,-0.25655361902926604,1.3069742818074888,0.9550218762313673,1.9070724559775802,0.24013334861470298,-0.15657014623897816,-0.3568736241903287,-0.12331590050833183,-0.18986101163713162,0.10845911446660461,0.631963801638392,0.4039669561578337,-0.023770392974690285,-1.0348382379290142,1.338799977605599,-0.6937989237284957,0.8584229744726526,1.93839687467804,0.9550218762313673,-0.023770392974690285,0.33853323249162104
3,475
Mitochondrial gene expression
34
65
2.303889
0.021229
Q9Y2R9,Q9H0R6,O95182,Q14197,Q9NYY8,Q96EY7,Q96QE5,Q00059,P82930,Q8NC60,P82673,Q96RP9,Q9BSK2,Q5T653,Q9Y2R0,Q9NX20,P82912,P42704,Q9HD33,Q16540,Q92552,P52815,Q969Z0,O75879,Q53R41,Q9BZE1,Q9NWS8,Q5JTZ9,Q567V2,O15091,Q07021,Q5T160,P49411,P34897
Processes and pathways
GO Biological process
msigdb_gobp
532,672,885,774,157,545,160,415,651,962,538,830,970,1090,67,474,694,1079,870,82,746,87,1148,338,92,1016,761,1137,853,980,376,251,997,994
3388,980,338,885,994,2629,1079,1890,997,87,538,694,1231,651,415,376,774,2346,82,92,853,1955,1137,251,1090,1404,1899,1609,3336,2024,962,1354,1245,746,1148,545,160,830,3150,3040,1667,2824,1514,970,2647,1016,672,1968,870,1675,1363,2994,761,474,157,1682,1867,67,1162,532,1323,2516,2454,2147,1213
-1.836765283536983,0.4366345847838189,1.1154307228188172,0.5018723958328761,0.4366345847838189,-0.5923034159930741,0.3712665741938593,-0.12331590050833183,0.4366345847838189,2.1258216652317476,0.8261633820993779,0.6644077422188699,0.27296683220001094,0.6968204986884444,0.9871621278015353,1.0513545753283584,0.5994884884196273,-0.3903896488181674,2.2502835286953093,2.094645697510917,0.5344429793834905,-0.15657014623897816,0.33853323249162104,1.3069742818074888,0.3712665741938593,0.1743647331482899,-0.12331590050833183,0.04241468851205189,-1.5198542631539218,-0.18986101163713162,0.4692696641062204,0.2072660552143123,0.27296683220001094,0.631963801638392,0.33853323249162104,0.8261633820993779,1.6240042815163254,0.5669816119272515,-1.1035684565388577,-0.9662858408639224,0.009339846996152005,-0.761667607945778,0.10845911446660461,0.4692696641062204,-0.5923034159930741,0.4366345847838189,0.6968204986884444,-0.15657014623897816,0.5344429793834905,0.009339846996152005,0.2072660552143123,-0.8979084274692133,0.631963801638392,0.922852047787671,1.6555599569329296,0.009339846996152005,-0.09009802404997375,2.405325005947192,0.33853323249162104,0.8584229744726526,0.24013334861470298,-0.4911696283708453,-0.4575373713799266,-0.25655361902926604,0.3057667222448112
3,475
EF-hand domain [IPR002048]
16
47
2.302747
0.021293
Q9UBC2,P0DP25,Q15293,Q96AY3,Q9NZM3,Q6NUK1,Q13813,Q96D71,Q9BPX6,Q14257,O95302,Q8IYU8,Q9Y680,O43852,P41208,Q9BRK5
Sequence
InterPro Domain
interpro_domain
529,65,234,400,306,516,594,239,240,233,44,179,289,146,617,197
1694,146,1073,806,1327,44,1474,65,1772,3284,1176,1774,1833,2584,2967,617,2168,1391,3208,1287,2481,1491,1132,594,233,2778,234,1445,516,1804,857,179,1855,400,912,239,240,197,1361,3018,1748,306,529,3380,677,2039,289
-0.023770392974690285,1.7185927649678452,0.3712665741938593,0.5669816119272515,0.2072660552143123,2.7443852320603073,0.10845911446660461,2.405325005947192,-0.05691626960112453,-1.4151355272862594,0.3057667222448112,-0.05691626960112453,-0.09009802404997375,-0.5585523596845848,-0.8979084274692133,0.7292022575003356,-0.2899558780062751,0.1743647331482899,-1.2070036199349412,0.24013334861470298,-0.4911696283708453,0.10845911446660461,0.33853323249162104,0.7615532030666726,1.338799977605599,-0.72771255680608,1.338799977605599,0.14142916094516933,0.8584229744726526,-0.05691626960112453,0.5344429793834905,1.5291785218097205,-0.09009802404997375,1.0192729716930538,0.5018723958328761,1.338799977605599,1.338799977605599,1.4658276708247233,0.2072660552143123,-0.9320754353215098,-0.023770392974690285,1.2113297287229814,0.8584229744726526,-1.765972455067393,0.6968204986884444,-0.18986101163713162,1.2432393107605846
3,475
Mitochondrial respiratory chain complex assembly
16
44
2.298873
0.021512
Q00059,Q9Y2R0,Q6DKK2,P03886,O43674,Q8TB37,O75306,O43920,Q9Y375,O95169,O75880,O95831,Q9P032,Q16795,Q9Y512,Q8N183
Processes and pathways
GO Biological process
msigdb_gobp
415,67,68,349,410,471,347,504,79,16,291,109,255,597,259,194
410,613,3343,1071,504,1634,347,841,291,721,16,2372,109,2159,349,2464,2470,1838,415,2010,2181,597,1898,2294,68,3170,194,3401,471,965,1514,970,3015,2993,868,2411,1209,255,2260,877,67,79,259,2265
0.9871621278015353,0.7292022575003356,-1.554860075681201,0.3712665741938593,0.8584229744726526,0.009339846996152005,1.0834071043843578,0.5344429793834905,1.2113297287229814,0.631963801638392,3.655839397007132,-0.42394413865700914,1.9696962435077099,-0.2899558780062751,1.0834071043843578,-0.4911696283708453,-0.4911696283708453,-0.09009802404997375,0.9871621278015353,-0.18986101163713162,-0.2899558780062751,0.7615532030666726,-0.12331590050833183,-0.3568736241903287,2.374363737780149,-1.1380011591326509,1.4658276708247233,-1.9433641305204705,0.922852047787671,0.4692696641062204,0.10845911446660461,0.4692696641062204,-0.9320754353215098,-0.8979084274692133,0.5344429793834905,-0.42394413865700914,0.3057667222448112,1.3069742818074888,-0.32339579074041863,0.5344429793834905,2.405325005947192,2.281339075443853,1.3069742818074888,-0.32339579074041863
3,475
Specific granule
11
36
2.29251
0.021876
P09110,Q13813,Q8WVQ1,P51790,P14923,Q6IAA8,Q9Y5K8,P30519,O00264,O00161,O00764
Localization
GO Cellular component
msigdb_gocc
246,594,77,50,177,599,554,62,337,555,158
555,2098,337,158,1693,1871,246,1941,177,1641,62,1595,50,1230,851,1184,1650,1439,594,1040,2537,957,2814,599,2438,2782,1805,1050,77,963,630,3100,1961,2559,3102,554
0.7938735177908782,-0.25655361902926604,1.1154307228188172,1.6240042815163254,-0.023770392974690285,-0.12331590050833183,1.3069742818074888,-0.15657014623897816,1.5291785218097205,0.009339846996152005,2.4362629820604664,0.04241468851205189,2.621407751431034,0.27296683220001094,0.5344429793834905,0.3057667222448112,0.009339846996152005,0.14142916094516933,0.7615532030666726,0.4039669561578337,-0.524841194797217,0.4692696641062204,-0.761667607945778,0.7615532030666726,-0.4575373713799266,-0.72771255680608,-0.05691626960112453,0.4039669561578337,2.281339075443853,0.4692696641062204,0.7292022575003356,-1.0348382379290142,-0.15657014623897816,-0.524841194797217,-1.0348382379290142,0.8261633820993779
3,475
Golgi cisterna membrane
7
22
2.288935
0.022083
Q99523,Q9P2E5,Q8WVQ1,Q10472,Q8N6G5,Q8NBZ7,P98194
Localization
GO Cellular component
msigdb_gocc
196,270,77,380,26,220,159
799,1476,816,159,539,379,1399,380,1001,2862,26,1567,220,1196,77,1570,196,2827,270,3389,2566,1870
0.5669816119272515,0.10845911446660461,0.5669816119272515,1.6240042815163254,0.8261633820993779,1.0513545753283584,0.1743647331482899,1.0513545753283584,0.4366345847838189,-0.7956643954387234,3.141647538878521,0.07545436686033442,1.3705980155545952,0.3057667222448112,2.281339075443853,0.07545436686033442,1.4658276708247233,-0.761667607945778,1.275120777065889,-1.836765283536983,-0.524841194797217,-0.09009802404997375
3,475
Respiratory electron transport chain
23
52
2.287751
0.022152
O43920,Q9UJS0,O95169,O95182,P14927,O43674,O00483,O75746,Q15149,P13073,P19404,P20674,O14548,P10606,Q9Y375,Q9UDW1,Q16795,O75489,P03886,O75306,O95168,O43676,Q16134
Processes and pathways
GO Biological process
msigdb_gobp
504,677,16,885,40,410,800,806,954,433,938,687,188,809,79,873,597,841,349,347,721,613,735
800,188,2418,410,613,3343,1071,504,1634,347,1635,841,806,721,16,885,2372,2159,2421,349,2464,2374,934,2160,1771,1475,809,433,2273,2332,40,1703,938,687,1224,2470,2423,1118,1391,1487,1838,954,735,2181,597,3122,1809,1155,873,677,79,2265
0.5669816119272515,1.4658276708247233,-0.4575373713799266,0.9871621278015353,0.7292022575003356,-1.554860075681201,0.3712665741938593,0.8584229744726526,0.009339846996152005,1.0834071043843578,0.009339846996152005,0.5344429793834905,0.5669816119272515,0.631963801638392,3.655839397007132,0.5018723958328761,-0.42394413865700914,-0.2899558780062751,-0.4575373713799266,1.0834071043843578,-0.4911696283708453,-0.42394413865700914,0.4692696641062204,-0.2899558780062751,-0.05691626960112453,0.10845911446660461,0.5669816119272515,0.9550218762313673,-0.3568736241903287,-0.3903896488181674,2.836385499712057,-0.023770392974690285,0.4692696641062204,0.6644077422188699,0.27296683220001094,-0.4911696283708453,-0.4575373713799266,0.33853323249162104,0.1743647331482899,0.10845911446660461,-0.09009802404997375,0.4692696641062204,0.631963801638392,-0.2899558780062751,0.7615532030666726,-1.0691809388636886,-0.05691626960112453,0.33853323249162104,0.5344429793834905,0.6968204986884444,2.281339075443853,-0.32339579074041863
3,475
Skin ulcer
6
31
2.278315
0.022708
P48735,O15460,O75874,Q04721,P01889,Q8IZA0
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
5,162,75,231,54,254
2151,1069,162,1762,2623,75,2841,769,54,432,2374,645,3180,1482,2424,3031,5,817,1228,1339,3117,1492,231,1893,569,1500,250,954,254,918,1158
-0.2899558780062751,0.3712665741938593,1.5924222429530126,-0.05691626960112453,-0.5923034159930741,2.281339075443853,-0.7956643954387234,0.5994884884196273,2.559784134405456,0.9550218762313673,-0.42394413865700914,0.6968204986884444,-1.1724794204274362,0.10845911446660461,-0.4575373713799266,-0.9662858408639224,4.667687825369334,0.5669816119272515,0.27296683220001094,0.2072660552143123,-1.0691809388636886,0.10845911446660461,1.338799977605599,-0.12331590050833183,0.7938735177908782,0.10845911446660461,1.3069742818074888,0.4692696641062204,1.3069742818074888,0.5018723958328761,0.33853323249162104
3,475
Vesicle docking
9
19
2.276547
0.022813
Q9UNK0,Q9H270,O14795,P56545,Q8WU76,Q7Z6M1,O60499,Q86Y82,Q13190
Processes and pathways
GO Biological process
msigdb_gobp
334,303,102,326,858,442,454,700,894
2098,102,2152,2763,454,1697,1535,2116,326,2000,948,1650,894,442,700,858,303,1680,334
-0.25655361902926604,2.0009706871850725,-0.2899558780062751,-0.72771255680608,0.922852047787671,-0.023770392974690285,0.07545436686033442,-0.25655361902926604,1.1474255928962198,-0.18986101163713162,0.4692696641062204,0.009339846996152005,0.5018723958328761,0.9550218762313673,0.6644077422188699,0.5344429793834905,1.2113297287229814,0.009339846996152005,1.1474255928962198
3,475
Intermediate filament protein, conserved site [IPR018039]
6
7
2.270381
0.023184
Q03252,P08670,P07197,P20700,P02545,Q16352
Sequence
InterPro Conserved site
interpro_conserved_site
311,71,202,374,432,821
432,202,71,374,812,311,821
0.9550218762313673,1.4341117147858753,2.343379067489768,1.0513545753283584,0.5669816119272515,1.1793918752131152,0.5669816119272515
3,475
Intermediate filament, rod domain [IPR039008]
6
7
2.270381
0.023184
Q03252,P08670,P07197,P20700,P02545,Q16352
Sequence
InterPro Domain
interpro_domain
311,71,202,374,432,821
432,202,71,374,812,311,821
0.9550218762313673,1.4341117147858753,2.343379067489768,1.0513545753283584,0.5669816119272515,1.1793918752131152,0.5669816119272515
3,475
Peptidyl lysine methylation
11
45
2.267152
0.023381
P51608,Q13573,P16402,P02545,P10412,P18615,Q96ST2,P16403,O96028,Q5T5X7,Q9H7B4
Processes and pathways
GO Biological process
msigdb_gobp
310,280,95,432,190,45,446,227,182,24,29
1825,1379,1934,1828,840,681,182,432,190,95,227,45,2216,1783,3085,310,2690,2533,458,1083,280,2777,3036,2238,657,24,823,903,3169,1802,1190,2403,2301,2306,788,709,446,2034,1310,29,2137,1749,2789,2510,1582
-0.09009802404997375,0.1743647331482899,-0.15657014623897816,-0.09009802404997375,0.5344429793834905,0.6644077422188699,1.4975165585697592,0.9550218762313673,1.4658276708247233,2.0634452922827657,1.338799977605599,2.7443852320603073,-0.32339579074041863,-0.05691626960112453,-1.0348382379290142,1.1793918752131152,-0.6599263948599569,-0.524841194797217,0.922852047787671,0.3712665741938593,1.2432393107605846,-0.72771255680608,-0.9662858408639224,-0.32339579074041863,0.6968204986884444,3.1720572250461965,0.5669816119272515,0.5018723958328761,-1.1380011591326509,-0.05691626960112453,0.3057667222448112,-0.42394413865700914,-0.3568736241903287,-0.3568736241903287,0.5994884884196273,0.6644077422188699,0.9550218762313673,-0.18986101163713162,0.24013334861470298,3.1112169427024057,-0.25655361902926604,-0.023770392974690285,-0.72771255680608,-0.4911696283708453,0.07545436686033442
3,475
Oxidative phosphorylation
25
63
2.266841
0.0234
O43920,O95169,Q9Y5K8,P14927,O43674,P06576,O00483,P56385,Q15904,P13073,P20674,P24539,O14548,P10606,P36542,Q9UDW1,Q16795,P22695,P03886,O75947,O75306,O95168,P36543,P48047,O43676
Processes and pathways
KEGG Pathways
msigdb_kegg
504,16,554,40,410,292,800,183,186,433,687,688,188,809,456,873,597,586,349,348,347,721,111,229,613
800,188,2418,410,613,3343,504,1634,347,3131,1635,841,348,3234,721,16,885,2372,2159,2421,3264,349,2464,292,1771,809,433,1989,1990,40,1703,938,687,1777,2051,1224,586,688,1078,2470,2423,3114,456,111,1645,229,1487,1838,1543,183,2476,3321,186,2181,597,3170,1411,1967,873,1465,2567,554,2265
0.5669816119272515,1.4658276708247233,-0.4575373713799266,0.9871621278015353,0.7292022575003356,-1.554860075681201,0.8584229744726526,0.009339846996152005,1.0834071043843578,-1.1035684565388577,0.009339846996152005,0.5344429793834905,1.0834071043843578,-1.2761913810585277,0.631963801638392,3.655839397007132,0.5018723958328761,-0.42394413865700914,-0.2899558780062751,-0.4575373713799266,-1.3455675981762987,1.0834071043843578,-0.4911696283708453,1.2113297287229814,-0.05691626960112453,0.5669816119272515,0.9550218762313673,-0.18986101163713162,-0.18986101163713162,2.836385499712057,-0.023770392974690285,0.4692696641062204,0.6644077422188699,-0.05691626960112453,-0.22318875028858487,0.27296683220001094,0.7615532030666726,0.6644077422188699,0.3712665741938593,-0.4911696283708453,-0.4575373713799266,-1.0691809388636886,0.922852047787671,1.9696962435077099,0.009339846996152005,1.338799977605599,0.10845911446660461,-0.09009802404997375,0.07545436686033442,1.4975165585697592,-0.4911696283708453,-1.4848985294257866,1.4975165585697592,-0.2899558780062751,0.7615532030666726,-1.1380011591326509,0.1743647331482899,-0.15657014623897816,0.5344429793834905,0.14142916094516933,-0.524841194797217,0.8261633820993779,-0.32339579074041863
3,475
oxidase
9
16
2.266233
0.023437
P20674,P10606,O14548,P36551,Q6ZRP7,Q8NB78,O75880,O75845,P13073
Functions
Panther Protein class
panther_protein_class
687,809,188,939,1004,10,291,585,433
188,1071,1828,585,291,809,433,1989,1990,1703,687,939,2171,2239,1004,10
1.4658276708247233,0.3712665741938593,-0.09009802404997375,0.7615532030666726,1.2113297287229814,0.5669816119272515,0.9550218762313673,-0.18986101163713162,-0.18986101163713162,-0.023770392974690285,0.6644077422188699,0.4692696641062204,-0.2899558780062751,-0.32339579074041863,0.4366345847838189,3.9257537181006645
3,475
Syntaxin binding
7
24
2.265288
0.023495
Q5SQN1,O95721,Q9UNK0,Q9H270,O14795,Q08379,O60499
Functions
GO Molecular function
msigdb_gomf
543,308,334,303,102,379,454
555,2098,102,2152,454,1168,308,2529,1837,1431,2339,379,543,1295,1405,1610,858,1196,1359,1670,303,2561,1680,334
0.7938735177908782,-0.25655361902926604,2.0009706871850725,-0.2899558780062751,0.922852047787671,0.3057667222448112,1.1793918752131152,-0.524841194797217,-0.09009802404997375,0.14142916094516933,-0.3903896488181674,1.0513545753283584,0.8261633820993779,0.24013334861470298,0.1743647331482899,0.04241468851205189,0.5344429793834905,0.3057667222448112,0.2072660552143123,0.009339846996152005,1.2113297287229814,-0.524841194797217,0.009339846996152005,1.1474255928962198
3,475
Oxidoreductase activity acting on the ch ch group of donors
9
27
2.261383
0.023736
Q8N4Q0,P09110,Q9BY49,O15254,O76062,Q9H7Z7,P11310,Q15392,Q14739
Functions
GO Molecular function
msigdb_gomf
236,246,167,169,69,180,89,91,250
169,69,246,89,616,1224,1034,2423,939,3206,3187,2171,3033,250,2977,315,91,1347,1092,236,3414,1012,167,180,868,920,1863
1.5608137029341247,2.343379067489768,1.3069742818074888,2.094645697510917,0.7292022575003356,0.27296683220001094,0.4039669561578337,-0.4575373713799266,0.4692696641062204,-1.2070036199349412,-1.1724794204274362,-0.2899558780062751,-0.9662858408639224,1.3069742818074888,-0.8979084274692133,1.1793918752131152,2.094645697510917,0.2072660552143123,0.3712665741938593,1.338799977605599,-2.050467446495352,0.4366345847838189,1.5924222429530126,1.5291785218097205,0.5344429793834905,0.5018723958328761,-0.09009802404997375
3,475
Wormian bones
7
19
2.255545
0.024099
Q96AY3,Q04721,O95831,Q32P28,O75844,Q14696,P02545
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
400,231,109,441,224,148,432
2417,479,224,109,432,2375,2582,1386,1393,231,1893,148,1554,441,2815,2673,400,918,2567
-0.4575373713799266,0.89065247147567,1.338799977605599,1.9696962435077099,0.9550218762313673,-0.42394413865700914,-0.5585523596845848,0.1743647331482899,0.1743647331482899,1.338799977605599,-0.12331590050833183,1.7185927649678452,0.07545436686033442,0.9550218762313673,-0.761667607945778,-0.6260946606959044,1.0192729716930538,0.5018723958328761,-0.524841194797217
3,475
Peroxisomal protein import
10
20
2.255489
0.024103
O15228,P09110,Q9BY49,O15254,O75874,O00116,O75521,P34913,O75381,Q15067
Processes and pathways
Reactome Pathways
msigdb_reactome
365,246,167,169,75,346,388,23,430,315
346,477,365,169,430,388,75,246,2467,847,23,1180,1482,1489,852,3464,315,2987,167,925
1.0834071043843578,0.89065247147567,1.0513545753283584,1.5608137029341247,0.9550218762313673,1.0192729716930538,2.281339075443853,1.3069742818074888,-0.4911696283708453,0.5344429793834905,3.1720572250461965,0.3057667222448112,0.10845911446660461,0.10845911446660461,0.5344429793834905,-3.6871244846496367,1.1793918752131152,-0.8979084274692133,1.5924222429530126,0.5018723958328761
3,475
Intrinsic component of mitochondrial inner membrane
10
33
2.247903
0.024582
Q96NB2,O60830,Q9Y2R0,Q9Y512,Q99595,Q6UXV4,Q16891,O75880,Q9H9P8,Q9NX63
Localization
GO Cellular component
msigdb_gocc
495,3,67,259,134,204,515,291,286,121
1426,1071,3,1217,291,1876,2376,1120,2171,1714,1551,2010,735,515,2348,736,1138,204,3401,1007,495,134,3445,1155,1418,286,1204,760,121,1063,67,553,259
0.14142916094516933,0.3712665741938593,4.902800840805222,0.27296683220001094,1.2113297287229814,-0.12331590050833183,-0.42394413865700914,0.33853323249162104,-0.2899558780062751,-0.023770392974690285,0.07545436686033442,-0.18986101163713162,0.631963801638392,0.8584229744726526,-0.3903896488181674,0.631963801638392,0.33853323249162104,1.4341117147858753,-1.9433641305204705,0.4366345847838189,0.89065247147567,1.8129476360755272,-2.5574276464493524,0.33853323249162104,0.1743647331482899,1.2432393107605846,0.3057667222448112,0.631963801638392,1.9070724559775802,0.4039669561578337,2.405325005947192,0.8261633820993779,1.3069742818074888
3,475
Cough
6
30
2.247614
0.024601
O15460,Q6UN15,P41440,P15924,Q9NR77,P01889
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
162,112,20,81,118,54
2151,1069,162,2370,769,54,2374,645,560,81,1225,1835,2730,2424,20,2692,2475,1037,542,112,1802,2867,2402,3241,3149,238,1458,118,2450,2680
-0.2899558780062751,0.3712665741938593,1.5924222429530126,-0.42394413865700914,0.5994884884196273,2.559784134405456,-0.42394413865700914,0.6968204986884444,0.7938735177908782,2.2502835286953093,0.27296683220001094,-0.09009802404997375,-0.6937989237284957,-0.4575373713799266,3.263161715062665,-0.6599263948599569,-0.4911696283708453,0.4039669561578337,0.8261633820993779,1.9696962435077099,-0.05691626960112453,-0.7956643954387234,-0.42394413865700914,-1.2761913810585277,-1.1035684565388577,1.338799977605599,0.14142916094516933,1.93839687467804,-0.4575373713799266,-0.6260946606959044
3,475
Apoptotic cleavage of cellular proteins
14
24
2.247586
0.024603
Q13813,Q14126,Q9UKV3,P20700,P08670,Q9HAW4,P51572,P15924,Q07157,Q9UDY2,Q15149,Q13464,Q16625,P02545
Processes and pathways
Reactome Pathways
msigdb_reactome
594,655,499,374,71,1058,816,81,459,874,954,152,154,432
432,71,81,374,1033,1783,1643,2055,2894,816,1839,2694,1288,459,152,594,655,954,154,1058,1256,874,2923,499
0.9550218762313673,2.343379067489768,2.2502835286953093,1.0513545753283584,0.4039669561578337,-0.05691626960112453,0.009339846996152005,-0.22318875028858487,-0.8297032421061233,0.5669816119272515,-0.09009802404997375,-0.6599263948599569,0.24013334861470298,0.922852047787671,1.6870894061892987,0.7615532030666726,0.6968204986884444,0.4692696641062204,1.6555599569329296,0.4039669561578337,0.27296683220001094,0.5344429793834905,-0.8297032421061233,0.89065247147567
3,475
Arrhythmogenic right ventricular cardiomyopathy arvc
8
13
2.246816
0.024652
Q14126,P35221,P19022,P14923,P05556,P15924,P50402,P02545
Processes and pathways
KEGG Pathways
msigdb_kegg
655,890,262,177,988,81,893,432
1694,432,988,1772,177,81,1116,262,890,1783,893,2065,655
-0.023770392974690285,0.9550218762313673,0.4366345847838189,-0.05691626960112453,1.5291785218097205,2.2502835286953093,0.33853323249162104,1.275120777065889,0.5018723958328761,-0.05691626960112453,0.5018723958328761,-0.22318875028858487,0.6968204986884444
3,475
Arrhythmogenic right ventricular cardiomyopathy
8
13
2.246816
0.024652
Q14126,P35221,P19022,P14923,P05556,P15924,P50402,P02545
Processes and pathways
WikiPathways
msigdb_wp
655,890,262,177,988,81,893,432
1694,432,988,1772,177,81,1116,262,890,1783,893,2065,655
-0.023770392974690285,0.9550218762313673,0.4366345847838189,-0.05691626960112453,1.5291785218097205,2.2502835286953093,0.33853323249162104,1.275120777065889,0.5018723958328761,-0.05691626960112453,0.5018723958328761,-0.22318875028858487,0.6968204986884444
3,475
Regulation of neurotransmitter levels
11
32
2.24456
0.024796
Q5SQN1,P0DP25,O95721,P50897,O14795,P56545,O75955,Q99808,P41440,Q06787,O00161
Processes and pathways
GO Biological process
msigdb_gobp
543,65,308,351,102,326,480,711,20,589,555
555,2098,102,2100,480,308,988,1770,65,1116,1535,1536,2846,2275,20,2222,2588,351,1432,2339,326,3062,589,1650,1085,1799,543,741,3122,711,1680,2413
0.7938735177908782,-0.25655361902926604,2.0009706871850725,-0.25655361902926604,0.89065247147567,1.1793918752131152,0.4366345847838189,-0.05691626960112453,2.405325005947192,0.33853323249162104,0.07545436686033442,0.07545436686033442,-0.7956643954387234,-0.3568736241903287,3.263161715062665,-0.32339579074041863,-0.5585523596845848,1.0834071043843578,0.14142916094516933,-0.3903896488181674,1.1474255928962198,-1.0005399910393864,0.7615532030666726,0.009339846996152005,0.3712665741938593,-0.05691626960112453,0.8261633820993779,0.631963801638392,-1.0691809388636886,0.6644077422188699,0.009339846996152005,-0.42394413865700914
3,475
Protein transmembrane transport
9
25
2.227283
0.025928
O60830,P10809,Q99595,Q9NS69,Q07820,O95831,Q9UGP8,O43615,O75381
Processes and pathways
GO Biological process
msigdb_gobp
3,536,134,39,377,109,223,273,430
1167,1426,273,3,2103,430,1381,109,932,536,1781,1431,1124,1339,1435,377,1239,3470,1294,2183,790,134,576,39,223
0.3057667222448112,0.14142916094516933,1.2432393107605846,4.902800840805222,-0.25655361902926604,0.9550218762313673,0.1743647331482899,1.9696962435077099,0.4692696641062204,0.8261633820993779,-0.05691626960112453,0.14142916094516933,0.33853323249162104,0.2072660552143123,0.14142916094516933,1.0513545753283584,0.27296683220001094,-4.829494488698679,0.24013334861470298,-0.2899558780062751,0.5994884884196273,1.8129476360755272,0.7938735177908782,2.8670084338016997,1.3705980155545952
3,475
Bromodomain [IPR001487]
10
18
2.225198
0.026068
Q8WWQ0,Q6PL18,Q92830,Q9NPI1,O15164,Q86U86,Q9ULU4,Q03164,Q12830,O60885
Sequence
InterPro Domain
interpro_domain
785,824,132,6,478,341,385,458,951,840
478,840,1388,945,458,951,2394,824,341,785,2442,132,6,1206,1629,1319,385,2954
0.89065247147567,0.5344429793834905,0.1743647331482899,0.4692696641062204,0.922852047787671,0.4692696641062204,-0.42394413865700914,0.5669816119272515,1.1154307228188172,0.5994884884196273,-0.4575373713799266,1.8129476360755272,4.40187579174786,0.3057667222448112,0.04241468851205189,0.24013334861470298,1.0513545753283584,-0.8637844753937785
3,475
Bromodomain-like superfamily [IPR036427]
10
18
2.225198
0.026068
Q8WWQ0,Q6PL18,Q92830,Q9NPI1,O15164,Q86U86,Q9ULU4,Q03164,Q12830,O60885
Sequence
InterPro Superfamily
interpro_homologous_superfamily
785,824,132,6,478,341,385,458,951,840
478,840,1388,945,458,951,2394,824,341,785,2442,132,6,1206,1629,1319,385,2954
0.89065247147567,0.5344429793834905,0.1743647331482899,0.4692696641062204,0.922852047787671,0.4692696641062204,-0.42394413865700914,0.5669816119272515,1.1154307228188172,0.5994884884196273,-0.4575373713799266,1.8129476360755272,4.40187579174786,0.3057667222448112,0.04241468851205189,0.24013334861470298,1.0513545753283584,-0.8637844753937785
3,475
Rac2 gtpase cycle
17
36
2.223219
0.026201
Q9Y2U8,P02786,Q14126,Q86XL3,O15173,Q8TAA9,P42167,Q8IZP0,Q9UH62,Q6IAA8,P05556,P49257,Q14739,Q07960,Q9Y512,Q5T2T1,P50402
Processes and pathways
Reactome Pathways
msigdb_reactome
258,933,655,959,38,604,691,703,1064,599,988,648,250,184,259,778,893
38,1172,933,988,1836,691,2114,648,893,2172,2226,2340,184,1549,1718,1551,655,1186,250,1953,778,2399,599,2438,959,703,604,1100,1573,2447,1463,1064,2198,258,2413,259
2.8670084338016997,0.3057667222448112,0.4692696641062204,0.4366345847838189,-0.09009802404997375,0.6644077422188699,-0.25655361902926604,0.6968204986884444,0.5018723958328761,-0.2899558780062751,-0.32339579074041863,-0.3903896488181674,1.4975165585697592,0.07545436686033442,-0.023770392974690285,0.07545436686033442,0.6968204986884444,0.3057667222448112,1.3069742818074888,-0.15657014623897816,0.5994884884196273,-0.42394413865700914,0.7615532030666726,-0.4575373713799266,0.4692696641062204,0.6644077422188699,0.7615532030666726,0.3712665741938593,0.07545436686033442,-0.4575373713799266,0.14142916094516933,0.4039669561578337,-0.2899558780062751,1.3069742818074888,-0.42394413865700914,1.3069742818074888
3,475
SNARE protein
7
12
2.217334
0.0266
Q5SQN1,O95721,Q9UNK0,P51809,O60499,Q86Y82,O00161
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
543,308,334,618,454,700,555
555,2152,454,1532,308,618,1650,894,543,700,1318,334
0.7938735177908782,-0.2899558780062751,0.922852047787671,0.07545436686033442,1.1793918752131152,0.7292022575003356,0.009339846996152005,0.5018723958328761,0.8261633820993779,0.6644077422188699,0.24013334861470298,1.1474255928962198
3,475
Intrinsic component of plasma membrane
33
88
2.215599
0.026719
Q8NAN2,Q8WTV0,Q99996,Q9BTU6,P19022,P30825,Q9UJS0,P41440,Q9H2J7,P20020,P05067,P04439,O00400,Q9UIQ6,P51790,Q99808,O43464,P01889,Q99805,P0DP25,Q9UNK0,P10321,O76062,Q86UP2,P35232,O00264,P33527,Q9H1Z9,Q99797,Q92542,Q04721,P07948,Q12907
Localization
GO Cellular component
msigdb_gocc
662,663,668,671,262,509,677,20,424,647,274,535,409,47,50,711,429,54,58,65,334,685,69,205,455,337,587,98,631,520,231,120,621
1026,337,409,2042,2996,1932,1693,2763,429,2684,2960,69,986,844,54,933,535,1769,274,1428,988,120,65,685,1986,2625,2931,810,1477,1116,2376,262,647,1943,991,1429,509,587,455,1333,2054,939,20,816,50,2901,1286,693,1128,1714,1000,231,1184,621,1236,1895,2595,1043,2290,1723,956,2491,205,3149,1351,662,3402,1050,663,520,3214,631,58,711,668,671,3465,1308,98,424,1312,1366,47,677,334,836,3387,2148
0.4039669561578337,1.1154307228188172,0.9871621278015353,-0.22318875028858487,-0.9320754353215098,-0.15657014623897816,-0.023770392974690285,-0.72771255680608,0.9550218762313673,-0.6599263948599569,-0.8979084274692133,2.343379067489768,0.4366345847838189,0.5344429793834905,2.559784134405456,0.4692696641062204,0.8261633820993779,-0.05691626960112453,1.2432393107605846,0.14142916094516933,0.4366345847838189,1.9070724559775802,2.405325005947192,0.6644077422188699,-0.18986101163713162,-0.5923034159930741,-0.8637844753937785,0.5669816119272515,0.10845911446660461,0.33853323249162104,-0.42394413865700914,1.275120777065889,0.6968204986884444,-0.15657014623897816,0.4366345847838189,0.14142916094516933,0.8584229744726526,0.7615532030666726,0.922852047787671,0.2072660552143123,-0.22318875028858487,0.4692696641062204,3.263161715062665,0.5669816119272515,2.621407751431034,-0.8297032421061233,0.24013334861470298,0.6644077422188699,0.33853323249162104,-0.023770392974690285,0.4366345847838189,1.338799977605599,0.3057667222448112,0.7292022575003356,0.27296683220001094,-0.12331590050833183,-0.5585523596845848,0.4039669561578337,-0.3568736241903287,-0.023770392974690285,0.4692696641062204,-0.4911696283708453,1.4341117147858753,-1.1035684565388577,0.2072660552143123,0.6968204986884444,-1.9433641305204705,0.4039669561578337,0.6968204986884444,0.8584229744726526,-1.2070036199349412,0.7292022575003356,2.5289382446116804,0.6644077422188699,0.6968204986884444,0.6968204986884444,-3.7644288180170276,0.24013334861470298,2.0634452922827657,0.9871621278015353,0.24013334861470298,0.2072660552143123,2.7443852320603073,0.6968204986884444,1.1474255928962198,0.5669816119272515,-1.8013419107859299,-0.25655361902926604
3,475
transcription cofactor
7
16
2.214959
0.026763
O14777,P56545,P51858,Q7Z4V5,Q9Y3E1,Q99417,O75475
Functions
Panther Protein class
panther_protein_class
503,326,9,175,53,214,123
2926,503,123,9,326,2739,1439,2775,2598,175,1297,2080,214,549,3349,53
-0.8637844753937785,0.8584229744726526,1.8757228615346935,3.9257537181006645,1.1474255928962198,-0.6937989237284957,0.14142916094516933,-0.72771255680608,-0.5585523596845848,1.5608137029341247,0.24013334861470298,-0.22318875028858487,1.402368545245139,0.8261633820993779,-1.554860075681201,2.590607268495023
3,475
Class i peroxisomal membrane protein import
7
11
2.214053
0.026825
O43808,P56589,O96011,Q9Y3D6,Q9NR77,O75381,Q5T8D3
Processes and pathways
Reactome Pathways
msigdb_reactome
534,41,886,52,118,430,658
534,430,886,1642,940,2173,41,658,2078,118,52
0.8261633820993779,0.9550218762313673,0.5018723958328761,0.009339846996152005,0.4692696641062204,-0.2899558780062751,2.775073997044326,0.6968204986884444,-0.22318875028858487,1.93839687467804,2.590607268495023
3,475
Regulation of mrna polyadenylation
12
15
2.21247
0.026934
Q6PD62,Q5VTR2,O75150,P18615,Q6PJT7,Q69YN4,O00267,P09012,Q16630,Q96MU7,O43809,Q8N684
Processes and pathways
GO Biological process
msigdb_gobp
903,418,1168,45,467,780,1110,147,899,522,1028,1143
1110,1028,1168,147,45,1227,2117,1398,899,418,780,903,467,1143,522
0.33853323249162104,0.4039669561578337,0.3057667222448112,1.7185927649678452,2.7443852320603073,0.27296683220001094,-0.25655361902926604,0.1743647331482899,0.5018723958328761,0.9871621278015353,0.5994884884196273,0.5018723958328761,0.922852047787671,0.33853323249162104,0.8584229744726526
3,475
Endopeptidase activity
19
67
2.208644
0.027199
Q6NTF9,Q16740,Q9Y4W6,Q9NZ08,Q8NB14,O43292,P49721,P28070,O14773,O43464,P28072,Q9BYT8,P22695,Q9Y4P1,Q5JRX3,O75844,Q92542,Q96TA2,P42892
Functions
GO Molecular function
msigdb_gomf
140,144,553,25,420,533,33,36,290,429,563,609,586,243,105,224,520,524,127
290,533,429,3106,1636,224,1474,2766,2467,1774,1117,586,3356,36,563,1330,2052,1480,690,2055,2219,127,2939,2586,2427,33,1648,3332,2228,3116,1839,2632,2341,1001,1235,2343,1951,2395,144,1799,105,2700,140,3426,2439,420,1145,1733,2493,520,2084,1053,2987,2404,2500,1620,524,1858,915,631,609,25,1862,3365,1687,243,553
1.2113297287229814,0.8261633820993779,0.9550218762313673,-1.0691809388636886,0.009339846996152005,1.338799977605599,0.10845911446660461,-0.72771255680608,-0.4911696283708453,-0.05691626960112453,0.33853323249162104,0.7615532030666726,-1.6250237525158988,2.8976096193276653,0.7938735177908782,0.2072660552143123,-0.22318875028858487,0.10845911446660461,0.6644077422188699,-0.22318875028858487,-0.32339579074041863,1.8443479643090066,-0.8637844753937785,-0.5585523596845848,-0.4575373713799266,3.0502926587362307,0.009339846996152005,-1.5198542631539218,-0.32339579074041863,-1.0691809388636886,-0.09009802404997375,-0.5923034159930741,-0.3903896488181674,0.4366345847838189,0.27296683220001094,-0.3903896488181674,-0.15657014623897816,-0.42394413865700914,1.750070167664919,-0.05691626960112453,2.0009706871850725,-0.6599263948599569,1.781521747408495,-2.2301359868108332,-0.4575373713799266,0.9871621278015353,0.33853323249162104,-0.023770392974690285,-0.4911696283708453,0.8584229744726526,-0.22318875028858487,0.4039669561578337,-0.8979084274692133,-0.42394413865700914,-0.4911696283708453,0.04241468851205189,0.8584229744726526,-0.09009802404997375,0.5018723958328761,0.7292022575003356,0.7615532030666726,3.1720572250461965,-0.09009802404997375,-1.6601825436071087,0.009339846996152005,1.338799977605599,0.8261633820993779
3,475
Proton transmembrane transporter activity
11
37
2.207697
0.027265
O14548,O75947,O00400,P36543,P48047,P06576,P36542,P51790,Q96ES6,P56385,P13073
Functions
GO Molecular function
msigdb_gomf
188,348,409,111,229,292,456,50,83,183,433
409,188,3131,348,3234,1327,2421,3264,1428,292,1771,809,1477,433,1990,687,1777,2051,688,1078,3114,456,111,1645,229,50,1543,183,2476,1714,1793,1411,83,873,1465,2567,554
0.9871621278015353,1.4658276708247233,-1.1035684565388577,1.0834071043843578,-1.2761913810585277,0.2072660552143123,-0.4575373713799266,-1.3455675981762987,0.14142916094516933,1.2113297287229814,-0.05691626960112453,0.5669816119272515,0.10845911446660461,0.9550218762313673,-0.18986101163713162,0.6644077422188699,-0.05691626960112453,-0.22318875028858487,0.6644077422188699,0.3712665741938593,-1.0691809388636886,0.922852047787671,1.9696962435077099,0.009339846996152005,1.338799977605599,2.621407751431034,0.07545436686033442,1.4975165585697592,-0.4911696283708453,-0.023770392974690285,-0.05691626960112453,0.1743647331482899,2.2502835286953093,0.5344429793834905,0.14142916094516933,-0.524841194797217,0.8261633820993779
3,475
Endosome organization
11
35
2.197001
0.02802
Q9H444,Q96ED9,Q9H270,Q15075,Q9H9H4,Q9BTU6,Q9Y3E7,P51790,Q6IAA8,Q9HD42,Q12768
Processes and pathways
GO Biological process
msigdb_gobp
168,133,303,489,304,671,679,50,599,198,313
927,2727,2102,1030,2172,50,1786,1125,313,1343,2009,489,2698,599,702,2302,1244,133,829,2309,2190,671,1915,303,168,304,198,2139,1421,1680,1368,2995,1823,1160,679
0.4692696641062204,-0.6937989237284957,-0.25655361902926604,0.4039669561578337,-0.2899558780062751,2.621407751431034,-0.05691626960112453,0.33853323249162104,1.1793918752131152,0.2072660552143123,-0.18986101163713162,0.89065247147567,-0.6599263948599569,0.7615532030666726,0.6644077422188699,-0.3568736241903287,0.27296683220001094,1.8129476360755272,0.5669816119272515,-0.3568736241903287,-0.2899558780062751,0.6968204986884444,-0.12331590050833183,1.2113297287229814,1.5924222429530126,1.2113297287229814,1.4658276708247233,-0.25655361902926604,0.1743647331482899,0.009339846996152005,0.2072660552143123,-0.8979084274692133,-0.05691626960112453,0.33853323249162104,0.6968204986884444
3,475
Response to toxic substance
8
50
2.193706
0.028257
P07099,P08183,P00374,O95831,Q15165,Q9Y5Z9,P34913,P07948
Processes and pathways
GO Biological process
msigdb_gobp
7,8,70,109,51,151,23,120
2621,1977,429,1828,1633,109,70,2797,934,1830,2160,7,120,8,1882,3344,3082,3423,3253,2379,481,2334,2656,3142,1885,2279,23,2054,3030,939,1484,2479,591,1550,462,2343,51,2488,178,1296,2641,1410,1196,788,3122,320,3262,669,925,151
-0.5923034159930741,-0.18986101163713162,0.9550218762313673,-0.09009802404997375,0.009339846996152005,1.9696962435077099,2.343379067489768,-0.761667607945778,0.4692696641062204,-0.09009802404997375,-0.2899558780062751,4.312955956439051,1.9070724559775802,3.9556492376216754,-0.12331590050833183,-1.554860075681201,-1.0348382379290142,-2.1580905392221044,-1.3108557315234917,-0.42394413865700914,0.89065247147567,-0.3903896488181674,-0.6260946606959044,-1.1035684565388577,-0.12331590050833183,-0.3568736241903287,3.1720572250461965,-0.22318875028858487,-0.9662858408639224,0.4692696641062204,0.10845911446660461,-0.4911696283708453,0.7615532030666726,0.07545436686033442,0.922852047787671,-0.3903896488181674,2.621407751431034,-0.4911696283708453,1.5291785218097205,0.24013334861470298,-0.5923034159930741,0.1743647331482899,0.3057667222448112,0.5994884884196273,-1.0691809388636886,1.1793918752131152,-1.3108557315234917,0.6968204986884444,0.5018723958328761,1.7185927649678452
3,475
Synaptic vesicle exocytosis
6
19
2.19261
0.028335
Q5SQN1,P0DP25,O95721,O14795,P56545,O00161
Processes and pathways
GO Biological process
msigdb_gobp
543,65,308,102,326,555
555,102,2100,308,1770,65,1116,1536,2588,2339,326,3062,589,1650,1085,1799,543,1680,2413
0.7938735177908782,2.0009706871850725,-0.25655361902926604,1.1793918752131152,-0.05691626960112453,2.405325005947192,0.33853323249162104,0.07545436686033442,-0.5585523596845848,-0.3903896488181674,1.1474255928962198,-1.0005399910393864,0.7615532030666726,0.009339846996152005,0.3712665741938593,-0.05691626960112453,0.8261633820993779,0.009339846996152005,-0.42394413865700914
3,475
Atp synthesis coupled electron transport
18
40
2.191048
0.028448
O75489,P20674,O14548,P10606,P14927,O43674,P03886,O75306,O95168,O43920,Q9Y375,O95169,O00483,Q9UDW1,O95182,Q16795,O43676,P13073
Processes and pathways
GO Biological process
msigdb_gobp
841,687,188,809,40,410,349,347,721,504,79,16,800,873,885,597,613,433
800,188,2418,410,613,3343,504,1634,347,1635,841,721,16,885,2372,2159,2421,349,2464,2160,1771,1475,809,433,2332,40,1703,938,687,2470,2423,1487,1838,2181,597,3122,1155,873,79,2265
0.5669816119272515,1.4658276708247233,-0.4575373713799266,0.9871621278015353,0.7292022575003356,-1.554860075681201,0.8584229744726526,0.009339846996152005,1.0834071043843578,0.009339846996152005,0.5344429793834905,0.631963801638392,3.655839397007132,0.5018723958328761,-0.42394413865700914,-0.2899558780062751,-0.4575373713799266,1.0834071043843578,-0.4911696283708453,-0.2899558780062751,-0.05691626960112453,0.10845911446660461,0.5669816119272515,0.9550218762313673,-0.3903896488181674,2.836385499712057,-0.023770392974690285,0.4692696641062204,0.6644077422188699,-0.4911696283708453,-0.4575373713799266,0.10845911446660461,-0.09009802404997375,-0.2899558780062751,0.7615532030666726,-1.0691809388636886,0.33853323249162104,0.5344429793834905,2.281339075443853,-0.32339579074041863
3,475
MFS transporter superfamily [IPR036259]
7
11
2.189026
0.028595
Q9H2V7,O00400,Q99808,Q96ES6,P41440,Q16625,Q14728
Sequence
InterPro Superfamily
interpro_homologous_superfamily
135,409,711,83,20,154,314
409,2625,20,2901,314,154,697,83,711,135,1164
0.9871621278015353,-0.5923034159930741,3.263161715062665,-0.8297032421061233,1.1793918752131152,1.6555599569329296,0.6644077422188699,2.2502835286953093,0.6644077422188699,1.8129476360755272,0.33853323249162104
3,475