term stringlengths 2 121 | overlap int64 6 281 | setsize int64 7 499 | score float64 1.96 10.6 | pval float64 0 0.05 | edge stringlengths 41 1.97k | type stringclasses 5 values | subtype stringclasses 24 values | subtype_key stringclasses 24 values | edge_idxs stringlengths 11 1.17k | ann_idxs stringlengths 19 2.31k | ann_vals stringlengths 124 9.94k | sig_size int64 2.2k 3.73k |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Protein targeting | 34 | 121 | 3.204527 | 0.001353 | Q99595,O60830,P46379,Q99523,Q5JRX3,Q9NS69,O60725,Q9P0J0,O95831,Q10713,Q9H9H4,P55786,O95429,O00165,P30536,Q9H444,O43681,Q9UHB9,P46934,P31751,Q14108,O75381,Q3ZCQ8,Q9Y3D6,Q8N4H5,Q9UII2,O43765,Q6ZWJ1,P56589,O14737,P43307,Q9Y512,P40855,Q15629 | Processes and pathways | GO Biological process | msigdb_gobp | 1,4,508,394,390,15,143,409,24,286,419,32,533,166,43,306,176,583,62,192,330,197,589,346,342,485,347,358,239,487,111,504,246,116 | 2586,166,1564,772,2978,1966,3177,487,659,937,807,598,176,347,143,4,197,1260,3213,1850,1704,2555,533,1094,24,1117,2644,2312,2717,1264,2844,2904,1265,1709,1452,3428,43,3116,192,2741,3078,3096,246,111,508,62,2564,1638,1662,2906,1298,32,239,3100,1788,2851,3184,2206,1145,3081,1824,2852,1753,286,1666,2992,330,1272,3403,1755,116,2395,1515,589,1828,390,358,1209,1013,1457,2868,1649,971,2087,342,2052,747,1766,866,2058,1219,394,2152,1,718,3250,1054,306,419,1395,736,15,1625,409,833,3065,872,583,2922,485,722,1533,2602,2943,755,1401,346,3126,504,2336,1702 | -0.5631937933047674,1.7636218040365772,-0.004375775863415211,0.5759724840094101,-0.8943015669385899,-0.2190483838022552,-1.1179452960132723,0.9038777056804731,0.6972889626491571,0.4190969319876285,0.541199255452286,0.7663438381457375,1.7138236090436918,1.1767019777664645,1.829875834701021,4.61882102015611,1.630619414996261,0.19066452603648326,-1.1742341486986292,-0.16519022238487766,-0.09357744939710187,-0.5449466965406411,0.8352060194424157,0.2963686288929385,3.264732786733322,0.27878413552863,-0.5997337881958207,-0.39951268421354885,-0.6546590794968076,0.19066452603648326,-0.7649300864530652,-0.8202787828880227,0.19066452603648326,-0.09357744939710187,0.06673759969946712,-1.9012348366427068,2.7890650119210334,-1.0244693677889274,1.6472810988328224,-0.6729984707451497,-0.9871961254841282,-1.005824441947442,1.4298541607079167,2.0276691307788863,0.8695655387205098,2.4998877799465182,-0.5449466965406411,-0.04001485370627771,-0.057855143918590056,-0.8202787828880227,0.17300089051442,3.1702091254103086,1.463421832352514,-1.005824441947442,-0.1293556878583202,-0.7649300864530652,-1.1179452960132723,-0.34522033918629164,0.26118655325487,-0.9871961254841282,-0.1472658952589451,-0.7649300864530652,-0.11145955440898236,1.295148685478845,-0.057855143918590056,-0.8943015669385899,1.2105997259678525,0.19066452603648326,-1.7459284461455995,-0.11145955440898236,2.0112411668915997,-0.43578144422450665,0.031208258927758886,0.7835773618879034,-0.1472658952589451,1.0747375459534367,1.1597362320078495,0.22595196061218203,0.3665765114452106,0.06673759969946712,-0.7833637290550592,-0.04001485370627771,0.4016029509522354,-0.2730352960413805,1.1936564655011561,-0.25502527446770934,0.6106959688336498,-0.11145955440898236,0.4889454962781681,-0.25502527446770934,0.22595196061218203,1.0747375459534367,-0.30909872995436094,5.037989622421626,0.645370002187069,-1.230677582860357,0.3314985089593542,1.2613624491146502,1.0406581721072192,0.11992981356626614,0.6280391487957254,3.6398950642313137,-0.02218841243594591,1.057703597794576,0.5237938951093771,-0.9499890775959331,0.4889454962781681,0.8007988770829282,-0.8202787828880227,0.9210161159169525,0.645370002187069,0.031208258927758886,-0.5631937933047674,-0.8387603079978073,0.6106959688336498,0.11992981356626614,1.1936564655011561,-1.0244693677889274,0.8867275244232448,-0.39951268421354885,-0.07570932756690205 | 3,477 |
Negative regulation of mrna processing | 12 | 23 | 3.171028 | 0.001519 | Q5VTR2,O75150,P18615,Q8WXF0,Q13242,O75494,Q07021,P38159,P61978,Q6PJT7,P98175,P22626 | Processes and pathways | GO Biological process | msigdb_gobp | 541,506,507,359,233,324,301,55,252,606,275,155 | 1089,1090,506,324,507,155,1572,2000,55,648,252,275,301,2179,2043,233,1174,923,541,1331,606,359,2501 | 0.2963686288929385,0.2963686288929385,0.8695655387205098,1.2105997259678525,0.8695655387205098,1.796769241269738,-0.004375775863415211,-0.23702965284823038,2.6126927177320334,0.7145708685502362,1.4130541216407417,1.328890738532374,1.2613624491146502,-0.3271522384422823,-0.25502527446770934,1.480189522091329,0.24357584178456979,0.43657813874424445,0.8352060194424157,0.1553239210492891,0.7663438381457375,1.1597362320078495,-0.49029638115367696 | 3,477 |
Mitochondrial protein import | 16 | 34 | 3.141474 | 0.001681 | Q99595,P21796,Q9UJS0,O60830,P06576,O95169,Q5JRX3,Q3ZCQ8,Q9NX63,Q9NS69,Q9Y512,Q8N4H5,Q13505,O43615,Q10713,O14925 | Processes and pathways | Reactome Pathways | msigdb_reactome | 1,128,322,4,262,104,390,589,241,15,504,342,276,598,286,659 | 659,598,4,3437,708,1260,809,1850,104,1117,262,1891,1264,1816,2617,128,1404,2949,2534,286,276,1755,589,390,342,1,3220,1395,15,241,322,2681,504,2336 | 0.6972889626491571,0.7663438381457375,4.61882102015611,-1.959802266913443,0.645370002187069,0.19066452603648326,0.541199255452286,-0.16519022238487766,2.093282645393226,0.27878413552863,1.3794214931092326,-0.18312871527243837,0.19066452603648326,-0.1472658952589451,-0.5814561396181898,1.9124649794523898,0.10221259161251053,-0.8572579084205912,-0.5267147969292446,1.295148685478845,1.328890738532374,-0.11145955440898236,0.7835773618879034,1.0747375459534367,1.1936564655011561,5.037989622421626,-1.1742341486986292,0.11992981356626614,3.6398950642313137,1.463421832352514,1.2275317897751026,-0.6180267920736977,0.8867275244232448,-0.39951268421354885 | 3,477 |
Intrinsic component of mitochondrial membrane | 16 | 48 | 3.1142 | 0.001844 | Q99595,Q15070,O60830,Q16134,Q5XKP0,O75431,Q9NX63,Q16891,Q9Y3D6,Q9Y512,Q9Y2R0,Q13505,Q8IWA4,Q9H9P8,Q96NB2,O14925 | Localization | GO Cellular component | msigdb_gocc | 1,539,4,266,713,708,241,728,346,504,23,276,696,420,95,659 | 659,1810,4,708,1198,1850,1704,1451,1117,1816,1570,2949,1973,1122,2041,276,539,1755,266,728,1828,713,744,886,696,2215,1615,3398,1650,95,1,1134,2364,3161,2655,2155,1838,420,1956,1775,2127,241,1531,873,23,346,1235,504 | 0.6972889626491571,-0.1472658952589451,4.61882102015611,0.645370002187069,0.22595196061218203,-0.16519022238487766,-0.09357744939710187,0.06673759969946712,0.27878413552863,-0.1472658952589451,-0.004375775863415211,-0.8572579084205912,-0.2190483838022552,0.27878413552863,-0.25502527446770934,1.328890738532374,0.8352060194424157,-0.11145955440898236,1.362588845676582,0.6280391487957254,-0.1472658952589451,0.645370002187069,0.6106959688336498,0.4715023827975977,0.6626885650713121,-0.34522033918629164,-0.02218841243594591,-1.7266029911540117,-0.04001485370627771,2.1587399725073695,5.037989622421626,0.27878413552863,-0.4176396446871264,-1.0805044162419772,-0.5997337881958207,-0.30909872995436094,-0.1472658952589451,1.0406581721072192,-0.20108142022241898,-0.11145955440898236,-0.29105976522553345,1.463421832352514,0.031208258927758886,0.4889454962781681,3.2804577505525687,1.1936564655011561,0.22595196061218203,0.8867275244232448 | 3,477 |
EF-Hand 1, calcium-binding site [IPR018247] | 9 | 40 | 3.098184 | 0.001947 | Q96AY3,O43852,Q14257,Q02818,Q9BRK5,O95302,Q9Y680,Q9UBV8,Q9NWM8 | Sequence | InterPro Binding site | interpro_binding_site | 2,226,36,101,169,8,141,207,119 | 1257,226,1568,809,1998,8,2901,231,1045,3311,1473,2903,1635,2240,3461,374,2532,1575,489,101,1577,985,36,2954,556,1648,2215,1615,2,460,1134,169,1394,2999,119,1919,2129,207,1778,141 | 0.19066452603648326,1.5136927513121756,-0.004375775863415211,0.541199255452286,-0.23702965284823038,4.528304336811979,-0.8202787828880227,1.496946485661057,0.3314985089593542,-1.3819626870605868,0.0489797444034831,-0.8202787828880227,-0.04001485370627771,-0.36330308096834,-2.697896024132171,1.125770842652169,-0.5267147969292446,-0.004375775863415211,0.9038777056804731,2.1096615598283077,-0.004375775863415211,0.3840961570394507,3.1070264246639914,-0.8572579084205912,0.8180084181768476,-0.04001485370627771,-0.34522033918629164,-0.02218841243594591,4.993329286903139,0.9552577561979099,0.27878413552863,1.7636218040365772,0.11992981356626614,-0.8943015669385899,2.0112411668915997,-0.18312871527243837,-0.29105976522553345,1.6139472546177651,-0.11145955440898236,1.846413879696845 | 3,477 |
MFS transporter superfamily [IPR036259] | 8 | 11 | 3.09238 | 0.001986 | O00400,P41440,Q99808,Q16625,Q9H2V7,P53985,Q9Y5Y0,Q14728 | Sequence | InterPro Superfamily | interpro_homologous_superfamily | 293,294,40,204,369,238,188,63 | 293,709,294,238,63,204,1794,392,40,369,188 | 1.278261105136215,0.645370002187069,1.278261105136215,1.463421832352514,2.4998877799465182,1.6139472546177651,-0.1293556878583202,1.0747375459534367,2.932574742931529,1.1427591973209943,1.6972035615388537 | 3,477 |
Calcium ion binding | 21 | 88 | 3.085566 | 0.002032 | Q96AY3,O95302,Q9UM22,Q9Y680,Q14257,Q9BRK5,O43681,P22681,Q9UJS0,Q04721,Q8WVQ1,Q96D71,Q9UBV8,P67936,Q8IYU8,O43852,Q02818,P0DP25,P55327,Q9NWM8,P41208 | Functions | GO Molecular function | msigdb_gomf | 2,8,12,141,36,169,176,429,322,446,333,460,207,328,351,226,101,231,362,119,374 | 1403,979,2230,176,1257,226,1568,3141,809,1377,1998,8,2420,2201,2901,2235,2342,231,2666,1045,2791,3311,1473,1199,3407,901,2903,2103,1635,1571,429,2888,2422,3393,2240,3461,374,2532,1575,2646,1354,362,2080,1407,328,489,1408,101,1577,446,3016,1579,2282,1905,985,2004,36,2597,2954,556,1613,1648,1649,2215,1615,351,2051,333,1074,2,1155,460,1134,169,2406,1394,2999,119,1919,1085,2129,207,2922,322,12,1778,1002,141 | 0.10221259161251053,0.3840961570394507,-0.36330308096834,1.7138236090436918,0.19066452603648326,1.5136927513121756,-0.004375775863415211,-1.061809293070439,0.541199255452286,0.11992981356626614,-0.23702965284823038,4.528304336811979,-0.4539381330689716,-0.34522033918629164,-0.8202787828880227,-0.36330308096834,-0.4176396446871264,1.496946485661057,-0.6180267920736977,0.3314985089593542,-0.7097240200629163,-1.3819626870605868,0.0489797444034831,0.22595196061218203,-1.7846374322856913,0.4540466096167885,-0.8202787828880227,-0.29105976522553345,-0.04001485370627771,-0.004375775863415211,1.0065327601008498,-0.8018132756130776,-0.4539381330689716,-1.7266029911540117,-0.36330308096834,-2.697896024132171,1.125770842652169,-0.5267147969292446,-0.004375775863415211,-0.5997337881958207,0.13763357601742993,1.1427591973209943,-0.2730352960413805,0.10221259161251053,1.2105997259678525,0.9038777056804731,0.10221259161251053,2.1096615598283077,-0.004375775863415211,0.972361052266646,-0.9128477418208648,-0.004375775863415211,-0.38140051285772825,-0.18312871527243837,0.3840961570394507,-0.23702965284823038,3.1070264246639914,-0.5631937933047674,-0.8572579084205912,0.8180084181768476,-0.02218841243594591,-0.04001485370627771,-0.04001485370627771,-0.34522033918629164,-0.02218841243594591,1.1767019777664645,-0.25502527446770934,1.2105997259678525,0.31394007341810976,4.993329286903139,0.26118655325487,0.9552577561979099,0.27878413552863,1.7636218040365772,-0.43578144422450665,0.11992981356626614,-0.8943015669385899,2.0112411668915997,-0.18312871527243837,0.31394007341810976,-0.29105976522553345,1.6139472546177651,-0.8202787828880227,1.2275317897751026,3.887479702546371,-0.11145955440898236,0.3840961570394507,1.846413879696845 | 3,477 |
Intrinsic component of mitochondrial inner membrane | 14 | 33 | 3.061866 | 0.0022 | Q99595,Q15070,O60830,Q16134,Q5XKP0,O75431,Q9NX63,Q16891,Q9Y512,Q9Y2R0,Q13505,Q9H9P8,Q96NB2,O14925 | Localization | GO Cellular component | msigdb_gocc | 1,539,4,266,713,708,241,728,504,23,276,420,95,659 | 659,1810,4,708,1198,1451,1570,2949,1973,2041,276,539,266,728,1828,713,744,886,3398,1650,95,1,3161,2155,1838,420,1956,2127,241,1531,23,1235,504 | 0.6972889626491571,-0.1472658952589451,4.61882102015611,0.645370002187069,0.22595196061218203,0.06673759969946712,-0.004375775863415211,-0.8572579084205912,-0.2190483838022552,-0.25502527446770934,1.328890738532374,0.8352060194424157,1.362588845676582,0.6280391487957254,-0.1472658952589451,0.645370002187069,0.6106959688336498,0.4715023827975977,-1.7266029911540117,-0.04001485370627771,2.1587399725073695,5.037989622421626,-1.0805044162419772,-0.30909872995436094,-0.1472658952589451,1.0406581721072192,-0.20108142022241898,-0.29105976522553345,1.463421832352514,0.031208258927758886,3.2804577505525687,0.22595196061218203,0.8867275244232448 | 3,477 |
Regulation of alternative mrna splicing via spliceosome | 17 | 29 | 3.05614 | 0.002242 | P51116,P51114,Q9Y2W1,Q9UHX1,Q01130,P52756,Q8WXF0,Q07666,Q9BWF3,Q92841,P09651,P62995,P38159,O75525,Q8IY67,P98175,Q15007 | Processes and pathways | GO Biological process | msigdb_gobp | 631,223,398,260,213,227,359,253,749,561,812,179,55,211,667,275,383 | 1090,211,812,1660,1096,2000,55,1121,223,631,227,179,275,3157,213,824,253,1174,383,1360,667,359,561,927,1015,749,260,398,2337 | 0.2963686288929385,1.580571395190101,0.541199255452286,-0.057855143918590056,0.2963686288929385,-0.23702965284823038,2.6126927177320334,0.27878413552863,1.530428347164649,0.7318406263618454,1.5136927513121756,1.7138236090436918,1.328890738532374,-1.0805044162419772,1.580571395190101,0.5237938951093771,1.4130541216407417,0.24357584178456979,1.0917600484003518,0.13763357601742993,0.6972889626491571,1.1597362320078495,0.8180084181768476,0.43657813874424445,0.3665765114452106,0.6106959688336498,1.3962432420799271,1.0747375459534367,-0.39951268421354885 | 3,477 |
metalloprotease | 11 | 26 | 3.025429 | 0.002483 | P55786,O95630,Q9NZ08,O75844,P42892,Q5JRX3,Q9UIQ6,Q9BYT8,P22695,Q7Z2K6,Q10713 | Functions | Panther Protein class | panther_protein_class | 32,411,126,122,11,390,81,408,298,157,286 | 505,1260,122,411,1686,3031,1353,298,3093,2107,11,1548,32,286,390,157,1984,2120,1724,718,408,720,3342,126,81,1235 | 0.8695655387205098,0.19066452603648326,1.978355565936782,1.0406581721072192,-0.07570932756690205,-0.9314102255969627,0.13763357601742993,1.2613624491146502,-1.005824441947442,-0.29105976522553345,3.9028885923934347,0.013423100007657314,3.1702091254103086,1.295148685478845,1.0747375459534367,1.796769241269738,-0.2190483838022552,-0.29105976522553345,-0.09357744939710187,0.645370002187069,1.057703597794576,0.645370002187069,-1.4389883090290831,1.9289526113250501,2.289192128383176,0.22595196061218203 | 3,477 |
Organic anion transport | 11 | 49 | 3.01595 | 0.002562 | Q9UJS0,O00400,P41440,Q9Y619,Q99808,P30825,P53985,Q9BQT8,P33527,Q96NB2,Q14728 | Processes and pathways | GO Biological process | msigdb_gobp | 322,293,294,165,40,75,238,18,123,95,63 | 293,2376,1197,1349,1740,809,2612,1451,2420,1706,2789,1687,1141,1707,709,1816,2617,373,2721,2314,75,123,294,2950,238,1787,1009,2594,63,3403,2251,636,1648,2005,2630,1334,95,40,18,852,611,1838,1956,1466,672,1841,322,2193,165 | 1.278261105136215,-0.43578144422450665,0.22595196061218203,0.13763357601742993,-0.11145955440898236,0.541199255452286,-0.5814561396181898,0.06673759969946712,-0.4539381330689716,-0.09357744939710187,-0.7097240200629163,-0.07570932756690205,0.26118655325487,-0.09357744939710187,0.645370002187069,-0.1472658952589451,-0.5814561396181898,1.125770842652169,-0.6546590794968076,-0.39951268421354885,2.37041584169695,1.978355565936782,1.278261105136215,-0.8572579084205912,1.463421832352514,-0.1293556878583202,0.3665765114452106,-0.5631937933047674,2.4998877799465182,-1.7459284461455995,-0.36330308096834,0.7318406263618454,-0.04001485370627771,-0.23702965284823038,-0.5814561396181898,0.1553239210492891,2.1587399725073695,2.932574742931529,3.5153541654854648,0.5063759878506557,0.7663438381457375,-0.1472658952589451,-0.20108142022241898,0.06673759969946712,0.6972889626491571,-0.1472658952589451,1.2275317897751026,-0.3271522384422823,1.780200641127462 | 3,477 |
Alpha/Beta hydrolase fold [IPR029058] | 10 | 27 | 3.009135 | 0.00262 | Q9H3G5,Q4J6C6,Q9HB40,Q9UMR5,P07099,Q9NUJ1,Q8NCC3,P34913,P42785,P50897 | Sequence | InterPro Superfamily | interpro_homologous_superfamily | 96,162,173,113,20,52,153,29,93,251 | 519,20,1743,3375,3115,29,2386,93,963,2932,251,162,3122,1150,1279,1436,153,821,3062,3354,1727,96,281,173,52,113,1138 | 0.8523917149803377,3.484139546224094,-0.11145955440898236,-1.61105182439162,-1.0244693677889274,3.217508323661947,-0.43578144422450665,2.1750800789820577,0.4016029509522354,-0.8387603079978073,1.4130541216407417,1.780200641127462,-1.0244693677889274,0.26118655325487,0.19066452603648326,0.08448186784031635,1.8133276304905637,0.541199255452286,-0.9499890775959331,-1.5152765788777773,-0.09357744939710187,2.1587399725073695,1.328890738532374,1.747032703853092,2.628771365546536,2.0276691307788863,0.27878413552863 | 3,477 |
Metalloprotease | 12 | 26 | 3.008377 | 0.002626 | P55786,O95630,O43847,O75844,P42892,Q5JRX3,Q9UIQ6,Q9BYT8,P09960,Q7Z2K6,O75976,Q9NZ08 | Functions | Protein Atlas Molecular function | protein_atlas_molecular_function | 32,411,505,122,11,390,81,408,110,157,317,126 | 2712,505,1260,122,317,411,110,3031,1353,11,1548,32,390,157,546,2120,1724,718,408,3048,720,2126,3342,126,81,1235 | -0.6546590794968076,0.8695655387205098,0.19066452603648326,1.978355565936782,1.2275317897751026,1.0406581721072192,2.0276691307788863,-0.9314102255969627,0.13763357601742993,3.9028885923934347,0.013423100007657314,3.1702091254103086,1.0747375459534367,1.796769241269738,0.8352060194424157,-0.29105976522553345,-0.09357744939710187,0.645370002187069,1.057703597794576,-0.9314102255969627,0.645370002187069,-0.29105976522553345,-1.4389883090290831,1.9289526113250501,2.289192128383176,0.22595196061218203 | 3,477 |
Cation transmembrane transporter activity | 17 | 73 | 2.990085 | 0.002789 | Q8NEW0,O75964,Q13423,O43772,O00400,P06576,Q9Y619,Q99808,Q15043,Q96ES6,P00846,P30825,Q70HW3,Q9HD20,P98194,P13073,Q96NB2 | Functions | GO Molecular function | msigdb_gomf | 248,257,161,97,293,262,165,40,331,392,10,75,229,216,466,400,95 | 293,1005,97,1349,2028,740,257,1998,2788,10,1742,2789,262,2201,2235,1707,1891,2343,1816,400,3010,901,2313,1168,1266,3180,3223,1143,1404,75,2107,903,1971,941,1972,2513,759,1787,1123,919,1382,3184,466,2041,1753,161,331,2251,1068,2970,229,733,1650,248,2360,527,392,95,40,1484,1837,611,1838,1956,216,1085,1113,1017,1735,2193,2194,770,165 | 1.278261105136215,0.3665765114452106,2.1423901995972563,0.13763357601742993,-0.25502527446770934,0.6106959688336498,1.3962432420799271,-0.23702965284823038,-0.7097240200629163,3.9336836738560215,-0.11145955440898236,-0.7097240200629163,1.3794214931092326,-0.34522033918629164,-0.36330308096834,-0.09357744939710187,-0.18312871527243837,-0.4176396446871264,-0.1472658952589451,1.057703597794576,-0.9128477418208648,0.4540466096167885,-0.39951268421354885,0.24357584178456979,0.19066452603648326,-1.1179452960132723,-1.1930313645227653,0.26118655325487,0.10221259161251053,2.37041584169695,-0.29105976522553345,0.4540466096167885,-0.2190483838022552,0.4190969319876285,-0.2190483838022552,-0.5084980423896142,0.5933404260508179,-0.1293556878583202,0.27878413552863,0.43657813874424445,0.11992981356626614,-1.1179452960132723,0.938142788391448,-0.25502527446770934,-0.11145955440898236,1.780200641127462,1.2105997259678525,-0.36330308096834,0.31394007341810976,-0.8757716419980323,1.5136927513121756,0.6280391487957254,-0.04001485370627771,1.4298541607079167,-0.4176396446871264,0.8523917149803377,1.0747375459534367,2.1587399725073695,2.932574742931529,0.0489797444034831,-0.1472658952589451,0.7663438381457375,-0.1472658952589451,-0.20108142022241898,1.580571395190101,0.31394007341810976,0.2963686288929385,0.3665765114452106,-0.09357744939710187,-0.3271522384422823,-0.3271522384422823,0.5933404260508179,1.780200641127462 | 3,477 |
Negative regulation of mrna splicing via spliceosome | 7 | 16 | 2.981812 | 0.002865 | Q13242,O75494,Q07021,P38159,P98175,P22626,P61978 | Processes and pathways | GO Biological process | msigdb_gobp | 233,324,301,55,275,155,252 | 1090,324,155,1572,2000,55,252,275,301,2179,2043,233,1174,923,359,2501 | 0.2963686288929385,1.2105997259678525,1.796769241269738,-0.004375775863415211,-0.23702965284823038,2.6126927177320334,1.4130541216407417,1.328890738532374,1.2613624491146502,-0.3271522384422823,-0.25502527446770934,1.480189522091329,0.24357584178456979,0.43657813874424445,1.1597362320078495,-0.49029638115367696 | 3,477 |
mRNA processing factor | 35 | 83 | 2.979813 | 0.002884 | Q07955,P33240,P19338,Q9UBB9,Q8IY67,Q13595,P98179,Q14011,Q15459,O95391,Q96PU8,P62310,P62995,Q8IWZ8,P38159,Q96PK6,Q96I25,P23246,Q01844,P35637,O60508,Q96E39,O75494,O75525,Q01130,Q92804,Q15233,Q86UA1,Q15637,Q8WXF0,Q13242,O95453,P62312,Q8WXF1,Q07666 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 258,645,644,274,667,287,34,35,675,175,304,178,179,437,55,579,578,569,445,76,323,206,324,211,213,89,603,729,726,359,233,614,618,377,253 | 1196,1469,1682,1022,1258,323,324,211,1261,810,2840,2715,175,614,2033,2139,1968,1263,644,569,645,76,55,1546,2692,178,618,3387,3451,3417,179,1098,34,213,445,253,258,2179,1643,3038,2043,840,2181,1433,233,1050,1174,287,35,826,603,3149,2046,675,726,3135,923,3060,729,437,1585,667,3299,888,359,377,89,206,2779,578,1251,579,304,1338,749,2781,1369,2919,274,3139,1233,1058,3309 | 0.22595196061218203,0.0489797444034831,-0.07570932756690205,0.34904397515841284,0.19066452603648326,1.2105997259678525,1.2105997259678525,1.580571395190101,0.19066452603648326,0.541199255452286,-0.7649300864530652,-0.6546590794968076,1.730433314315435,0.7490982712358505,-0.25502527446770934,-0.30909872995436094,-0.2190483838022552,0.19066452603648326,0.7145708685502362,0.8007988770829282,0.7145708685502362,2.37041584169695,2.6126927177320334,0.013423100007657314,-0.6363352046117817,1.7138236090436918,0.7490982712358505,-1.6494929110757173,-2.215730782294194,-1.842847311166223,1.7138236090436918,0.2963686288929385,3.1070264246639914,1.580571395190101,0.972361052266646,1.4130541216407417,1.3962432420799271,-0.3271522384422823,-0.04001485370627771,-0.9314102255969627,-0.25502527446770934,0.5063759878506557,-0.3271522384422823,0.08448186784031635,1.480189522091329,0.3314985089593542,0.24357584178456979,1.295148685478845,3.1070264246639914,0.5237938951093771,0.7663438381457375,-1.061809293070439,-0.25502527446770934,0.6799948733270359,0.6280391487957254,-1.0431309642750133,0.43657813874424445,-0.9499890775959331,0.6280391487957254,0.9894527093654699,-0.004375775863415211,0.6972889626491571,-1.3440352974719634,0.4715023827975977,1.1597362320078495,1.125770842652169,2.2240426346319078,1.6139472546177651,-0.6913534327057209,0.8007988770829282,0.20831486901201274,0.8007988770829282,1.2613624491146502,0.1553239210492891,0.6106959688336498,-0.6913534327057209,0.13763357601742993,-0.8202787828880227,1.3457452705931343,-1.0431309642750133,0.22595196061218203,0.3314985089593542,-1.3629900695977135 | 3,477 |
Nuclear inner membrane | 10 | 23 | 2.952485 | 0.003152 | P20700,Q9H1E5,Q9UH99,Q99720,Q9Y2U8,Q03252,P62995,P43243,O75844,Q14728 | Localization | GO Cellular component | msigdb_gocc | 159,290,249,105,475,490,179,465,122,63 | 122,916,1471,159,2725,465,918,2771,179,490,984,63,1304,1126,945,1670,2015,547,105,2502,290,249,475 | 1.978355565936782,0.43657813874424445,0.0489797444034831,1.780200641127462,-0.6546590794968076,0.938142788391448,0.43657813874424445,-0.6913534327057209,1.7138236090436918,0.9038777056804731,0.3840961570394507,2.4998877799465182,0.17300089051442,0.27878413552863,0.4190969319876285,-0.057855143918590056,-0.23702965284823038,0.8352060194424157,2.093282645393226,-0.49029638115367696,1.295148685478845,1.4298541607079167,0.938142788391448 | 3,477 |
Steroid binding | 10 | 24 | 2.928466 | 0.003406 | P21796,Q9BZF3,P35610,O15173,Q14108,P30536,P04150,P45880,Q9H4L5,O00264 | Functions | GO Molecular function | msigdb_gomf | 128,7,536,196,330,43,389,79,180,250 | 250,553,196,1500,1425,1931,389,1742,2235,128,2237,1745,43,536,1120,79,3185,330,3377,1077,2154,850,7,180 | 1.4130541216407417,0.8180084181768476,1.630619414996261,0.031208258927758886,0.08448186784031635,-0.20108142022241898,1.0747375459534367,-0.11145955440898236,-0.36330308096834,1.9124649794523898,-0.36330308096834,-0.11145955440898236,2.7890650119210334,0.8352060194424157,0.27878413552863,2.3379546179921205,-1.1179452960132723,1.2105997259678525,-1.61105182439162,0.31394007341810976,-0.30909872995436094,0.5063759878506557,4.573593931116834,1.7138236090436918 | 3,477 |
Intrinsic component of plasma membrane | 23 | 88 | 2.919105 | 0.00351 | P04439,Q8WTV0,O00400,P41440,Q99808,O15118,Q9UJS0,Q04721,O96005,Q9NR28,Q99805,Q15043,P30825,P10321,Q9UIQ6,Q9BTU6,P36551,P0DP25,P53985,Q9H1Z9,P33527,P05067,O00264 | Localization | GO Cellular component | msigdb_gocc | 520,19,293,294,40,553,322,446,568,71,593,331,75,326,81,483,356,231,238,118,123,124,250 | 1403,250,293,1966,1880,553,1290,1967,807,2339,1093,916,1351,568,2665,1686,520,1742,124,2789,1687,917,231,326,2480,709,2980,857,1816,901,1570,2103,2313,1265,3223,2422,75,123,2170,1604,903,356,294,1298,759,238,3246,1787,3197,2041,1009,446,2594,1825,2537,1905,3388,331,1791,2045,2251,2574,970,2630,1436,1520,2089,1390,19,1800,747,718,593,40,1523,483,1727,1837,118,611,71,2157,81,322,855,2193,1002,1116 | 0.10221259161251053,1.4130541216407417,1.278261105136215,-0.2190483838022552,-0.18312871527243837,0.8180084181768476,0.17300089051442,-0.2190483838022552,0.541199255452286,-0.4176396446871264,0.2963686288929385,0.43657813874424445,0.13763357601742993,0.8007988770829282,-0.6180267920736977,-0.07570932756690205,0.8523917149803377,-0.11145955440898236,1.9618978796135385,-0.7097240200629163,-0.07570932756690205,0.43657813874424445,1.496946485661057,1.2105997259678525,-0.49029638115367696,0.645370002187069,-0.8943015669385899,0.4889454962781681,-0.1472658952589451,0.4540466096167885,-0.004375775863415211,-0.29105976522553345,-0.39951268421354885,0.19066452603648326,-1.1930313645227653,-0.4539381330689716,2.37041584169695,1.978355565936782,-0.3271522384422823,-0.02218841243594591,0.4540466096167885,1.1597362320078495,1.278261105136215,0.17300089051442,0.5933404260508179,1.463421832352514,-1.230677582860357,-0.1293556878583202,-1.1366911787908272,-0.25502527446770934,0.3665765114452106,0.972361052266646,-0.5631937933047674,-0.1472658952589451,-0.5267147969292446,-0.18312871527243837,-1.6687418267462384,1.2105997259678525,-0.1293556878583202,-0.25502527446770934,-0.36330308096834,-0.5449466965406411,0.4016029509522354,-0.5814561396181898,0.08448186784031635,0.031208258927758886,-0.2730352960413805,0.11992981356626614,3.4997508506844,-0.1293556878583202,0.6106959688336498,0.645370002187069,0.7835773618879034,2.932574742931529,0.031208258927758886,0.9210161159169525,-0.09357744939710187,-0.1472658952589451,2.0112411668915997,0.7663438381457375,2.419037471494315,-0.30909872995436094,2.289192128383176,1.2275317897751026,0.5063759878506557,-0.3271522384422823,0.3840961570394507,0.2963686288929385 | 3,477 |
RNA recognition motif domain, eukaryote [IPR003954] | 7 | 12 | 2.919028 | 0.003511 | Q14011,Q9UHX1,Q96E39,P38159,Q01130,Q01085,Q96I25 | Sequence | InterPro Domain | interpro_domain | 35,260,206,55,213,339,578 | 1688,644,55,339,213,1384,35,1692,206,578,260,1058 | -0.07570932756690205,0.7145708685502362,2.6126927177320334,1.1936564655011561,1.580571395190101,0.11992981356626614,3.1070264246639914,-0.07570932756690205,1.6139472546177651,0.8007988770829282,1.3962432420799271,0.3314985089593542 | 3,477 |
Metalloendopeptidase activity | 7 | 14 | 2.918929 | 0.003512 | O43847,P42892,Q5JRX3,P22695,Q9BYT8,O75844,Q10713 | Functions | GO Molecular function | msigdb_gomf | 505,11,390,298,408,122,286 | 505,1260,122,1353,298,11,1548,286,390,546,1724,718,408,1235 | 0.8695655387205098,0.19066452603648326,1.978355565936782,0.13763357601742993,1.2613624491146502,3.9028885923934347,0.013423100007657314,1.295148685478845,1.0747375459534367,0.8352060194424157,-0.09357744939710187,0.645370002187069,1.057703597794576,0.22595196061218203 | 3,477 |
Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen | 11 | 34 | 2.871647 | 0.004083 | O75845,Q16850,Q9UPP1,P30519,Q6UW02,Q9BU89,O15460,P61457,P13674,Q9Y2Z9,P09601 | Functions | GO Molecular function | msigdb_gomf | 443,350,100,5,296,425,208,401,217,30,212 | 2447,3392,1290,208,2760,1092,1927,3141,443,1351,1999,212,217,1428,858,5,401,2177,2282,674,1274,350,525,1518,296,987,1248,2893,1072,425,1368,100,1631,30 | -0.4721097617635663,-1.7266029911540117,0.17300089051442,1.5972645904672784,-0.6913534327057209,0.2963686288929385,-0.20108142022241898,-1.061809293070439,0.972361052266646,0.13763357601742993,-0.23702965284823038,1.580571395190101,1.5638676413060804,0.08448186784031635,0.4889454962781681,4.573593931116834,1.057703597794576,-0.3271522384422823,-0.38140051285772825,0.6799948733270359,0.19066452603648326,1.1767019777664645,0.8523917149803377,0.031208258927758886,1.278261105136215,0.3840961570394507,0.20831486901201274,-0.8018132756130776,0.31394007341810976,1.0236012369190428,0.13763357601742993,2.1260307366165443,-0.02218841243594591,3.2017502522530474 | 3,477 |
Rna stabilization | 12 | 28 | 2.86445 | 0.004177 | O60506,P67809,Q9Y2W1,Q14011,Q13151,Q08J23,P35637,O95453,Q9H814,Q13148,Q92804,P98175 | Processes and pathways | GO Biological process | msigdb_gobp | 256,444,398,35,422,295,76,614,149,402,89,275 | 256,2530,1539,614,900,1688,76,444,275,3157,1642,295,402,422,35,841,827,2252,2007,3160,1335,89,654,1805,1676,149,1840,398 | 1.3962432420799271,-0.5267147969292446,0.013423100007657314,0.7490982712358505,0.4540466096167885,-0.07570932756690205,2.37041584169695,0.972361052266646,1.328890738532374,-1.0805044162419772,-0.04001485370627771,1.278261105136215,1.057703597794576,1.0236012369190428,3.1070264246639914,0.5063759878506557,0.5237938951093771,-0.36330308096834,-0.23702965284823038,-1.0805044162419772,0.1553239210492891,2.2240426346319078,0.7145708685502362,-0.1293556878583202,-0.057855143918590056,1.829875834701021,-0.1472658952589451,1.0747375459534367 | 3,477 |
Metalloprotease | 12 | 37 | 2.861331 | 0.004219 | P55786,O95630,O43847,Q9NZ08,O75844,P42892,Q5JRX3,Q9UIQ6,Q9BYT8,P22695,Q7Z2K6,Q10713 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 32,411,505,126,122,11,390,81,408,298,157,286 | 2416,2712,1924,505,1260,122,411,1686,1893,3031,1353,298,3093,2107,11,2591,1548,32,286,2774,3040,390,1981,157,1984,1438,546,1154,2120,1724,718,1835,408,3342,126,81,1235 | -0.4539381330689716,-0.6546590794968076,-0.20108142022241898,0.8695655387205098,0.19066452603648326,1.978355565936782,1.0406581721072192,-0.07570932756690205,-0.18312871527243837,-0.9314102255969627,0.13763357601742993,1.2613624491146502,-1.005824441947442,-0.29105976522553345,3.9028885923934347,-0.5631937933047674,0.013423100007657314,3.1702091254103086,1.295148685478845,-0.6913534327057209,-0.9314102255969627,1.0747375459534367,-0.2190483838022552,1.796769241269738,-0.2190483838022552,0.08448186784031635,0.8352060194424157,0.26118655325487,-0.29105976522553345,-0.09357744939710187,0.645370002187069,-0.1472658952589451,1.057703597794576,-1.4389883090290831,1.9289526113250501,2.289192128383176,0.22595196061218203 | 3,477 |
Negative regulation of rna catabolic process | 18 | 35 | 2.829732 | 0.004659 | O60506,Q15717,P67809,Q9Y2W1,Q14011,Q99729,Q13151,Q96HR8,Q08J23,Q06787,P35637,O95453,Q14103,Q9H814,Q13148,Q92804,P98175,A2RRP1 | Processes and pathways | GO Biological process | msigdb_gobp | 256,827,444,398,35,163,422,654,295,824,76,614,841,149,402,89,275,876 | 876,256,2530,1539,614,900,1688,76,2725,444,275,3157,824,1642,295,402,422,35,841,2110,827,2252,2007,3160,1335,89,654,163,2918,1805,1676,1730,149,1840,398 | 0.4715023827975977,1.3962432420799271,-0.5267147969292446,0.013423100007657314,0.7490982712358505,0.4540466096167885,-0.07570932756690205,2.37041584169695,-0.6546590794968076,0.972361052266646,1.328890738532374,-1.0805044162419772,0.5237938951093771,-0.04001485370627771,1.278261105136215,1.057703597794576,1.0236012369190428,3.1070264246639914,0.5063759878506557,-0.29105976522553345,0.5237938951093771,-0.36330308096834,-0.23702965284823038,-1.0805044162419772,0.1553239210492891,2.2240426346319078,0.7145708685502362,1.780200641127462,-0.8202787828880227,-0.1293556878583202,-0.057855143918590056,-0.09357744939710187,1.829875834701021,-0.1472658952589451,1.0747375459534367 | 3,477 |
Metallopeptidase activity | 16 | 40 | 2.822328 | 0.004768 | P55786,O95630,O43847,Q9NZ08,P36551,O75844,P42892,Q5JRX3,Q9UIQ6,Q9BYT8,P22695,P09960,Q9HD42,Q7Z2K6,O75976,Q10713 | Functions | GO Molecular function | msigdb_gomf | 32,411,505,126,356,122,11,390,81,408,298,110,187,157,317,286 | 2416,2712,1924,505,1260,122,317,411,1686,110,3031,1353,298,3093,356,11,2742,2591,1548,32,286,390,3060,1981,157,546,2362,3459,2120,1724,718,408,3048,187,720,2126,3342,126,81,1235 | -0.4539381330689716,-0.6546590794968076,-0.20108142022241898,0.8695655387205098,0.19066452603648326,1.978355565936782,1.2275317897751026,1.0406581721072192,-0.07570932756690205,2.0276691307788863,-0.9314102255969627,0.13763357601742993,1.2613624491146502,-1.005824441947442,1.1597362320078495,3.9028885923934347,-0.6729984707451497,-0.5631937933047674,0.013423100007657314,3.1702091254103086,1.295148685478845,1.0747375459534367,-0.9499890775959331,-0.2190483838022552,1.796769241269738,0.8352060194424157,-0.4176396446871264,-2.616618108965407,-0.29105976522553345,-0.09357744939710187,0.645370002187069,1.057703597794576,-0.9314102255969627,1.6972035615388537,0.645370002187069,-0.29105976522553345,-1.4389883090290831,1.9289526113250501,2.289192128383176,0.22595196061218203 | 3,477 |
Negative regulation of mrna catabolic process | 9 | 26 | 2.801446 | 0.005087 | O60506,Q14011,Q9Y2W1,Q99729,Q13151,P35637,Q13148,Q92804,P98175 | Processes and pathways | GO Biological process | msigdb_gobp | 256,35,398,163,422,76,402,89,275 | 876,256,1539,900,1688,76,444,275,3157,824,1642,402,422,35,841,2110,827,2252,2007,3160,1335,89,163,1805,1840,398 | 0.4715023827975977,1.3962432420799271,0.013423100007657314,0.4540466096167885,-0.07570932756690205,2.37041584169695,0.972361052266646,1.328890738532374,-1.0805044162419772,0.5237938951093771,-0.04001485370627771,1.057703597794576,1.0236012369190428,3.1070264246639914,0.5063759878506557,-0.29105976522553345,0.5237938951093771,-0.36330308096834,-0.23702965284823038,-1.0805044162419772,0.1553239210492891,2.2240426346319078,1.780200641127462,-0.1293556878583202,-0.1472658952589451,1.0747375459534367 | 3,477 |
Primary adrenal insufficiency | 6 | 16 | 2.767418 | 0.00565 | Q13423,Q969G3,O75381,P56589,P40855,P31749 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 161,360,197,239,246,183 | 197,1813,3030,389,1428,183,246,2281,239,1665,161,360,1219,1806,1440,2066 | 1.630619414996261,-0.1472658952589451,-0.9314102255969627,1.0747375459534367,0.08448186784031635,1.6972035615388537,1.4298541607079167,-0.38140051285772825,1.463421832352514,-0.057855143918590056,1.780200641127462,1.1597362320078495,0.22595196061218203,-0.1293556878583202,0.08448186784031635,-0.25502527446770934 | 3,477 |
Insulin receptor signaling pathway | 16 | 32 | 2.765584 | 0.005682 | P31751,Q9UQB8,P25054,P18031,Q6ZWJ1,Q15043,Q9UKG1,Q9BZF1,Q9H1E3,Q9H2Y7,Q9HCD5,Q8TBX8,Q96EB6,P31749,P05771,P43490 | Processes and pathways | GO Biological process | msigdb_gobp | 192,69,414,724,358,331,564,850,562,893,517,406,547,183,127,787 | 1059,897,2553,2101,127,2140,1353,724,414,183,192,787,1662,2174,1048,1610,3073,331,2005,358,1649,406,1186,1154,547,850,562,893,517,564,69,1536 | 0.31394007341810976,0.4540466096167885,-0.5449466965406411,-0.29105976522553345,1.9124649794523898,-0.30909872995436094,0.13763357601742993,0.6280391487957254,1.0406581721072192,1.6972035615388537,1.6472810988328224,0.5585921060824289,-0.057855143918590056,-0.3271522384422823,0.3314985089593542,-0.02218841243594591,-0.9685843575272131,1.2105997259678525,-0.23702965284823038,1.1597362320078495,-0.04001485370627771,1.057703597794576,0.24357584178456979,0.26118655325487,0.8352060194424157,0.5063759878506557,0.8180084181768476,0.4715023827975977,0.8695655387205098,0.8180084181768476,2.435226048707906,0.031208258927758886 | 3,477 |
Negative regulation of autophagy | 8 | 27 | 2.763387 | 0.00572 | Q9NRR5,Q8IXJ6,P30536,Q9H444,O15118,Q08379,P09601,P31749 | Processes and pathways | GO Biological process | msigdb_gobp | 321,6,43,306,553,500,212,183 | 553,1739,2029,1815,2381,2139,212,1743,43,183,1507,2144,2461,2178,1099,500,1014,6,2117,1337,306,1597,1732,321,2157,833,657 | 0.8180084181768476,-0.11145955440898236,-0.25502527446770934,-0.1472658952589451,-0.43578144422450665,-0.30909872995436094,1.580571395190101,-0.11145955440898236,2.7890650119210334,1.6972035615388537,0.031208258927758886,-0.30909872995436094,-0.4721097617635663,-0.3271522384422823,0.2963686288929385,0.8867275244232448,0.3665765114452106,4.573593931116834,-0.29105976522553345,0.1553239210492891,1.2613624491146502,-0.004375775863415211,-0.09357744939710187,1.2275317897751026,-0.30909872995436094,0.5237938951093771,0.7145708685502362 | 3,477 |
Receptor | 14 | 39 | 2.755716 | 0.005856 | Q9Y2W1,P24390,Q04721,O15173,Q99523,Q14108,Q99720,P30825,P04150,Q9NS69,O15118,Q8WTV0,Q9Y5Y0,O00264 | Functions | Protein Atlas Molecular function | protein_atlas_molecular_function | 398,570,446,196,394,330,105,75,389,15,553,19,188,250 | 250,553,196,1375,613,1686,389,1687,2643,2312,1378,2761,2480,2980,857,1353,1265,570,75,1604,3197,446,2537,330,1304,2045,2251,19,2360,394,2153,105,15,3109,914,398,1702,188,3295 | 1.4130541216407417,0.8180084181768476,1.630619414996261,0.11992981356626614,0.7490982712358505,-0.07570932756690205,1.0747375459534367,-0.07570932756690205,-0.5997337881958207,-0.39951268421354885,0.11992981356626614,-0.6913534327057209,-0.49029638115367696,-0.8943015669385899,0.4889454962781681,0.13763357601742993,0.19066452603648326,0.8007988770829282,2.37041584169695,-0.02218841243594591,-1.1366911787908272,0.972361052266646,-0.5267147969292446,1.2105997259678525,0.17300089051442,-0.25502527446770934,-0.36330308096834,3.4997508506844,-0.4176396446871264,1.0747375459534367,-0.30909872995436094,2.093282645393226,3.6398950642313137,-1.005824441947442,0.4540466096167885,1.0747375459534367,-0.07570932756690205,1.6972035615388537,-1.325098301639506 | 3,477 |
Morphological abnormality of the pyramidal tract | 9 | 25 | 2.749519 | 0.005968 | O00400,Q9Y619,P00846,P35637,Q13501,Q13148,O95831,Q9H9P8,Q12768 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 293,165,10,76,403,402,24,420,538 | 293,2196,2378,2508,2664,24,10,709,1503,1380,76,2794,1510,538,2352,402,403,1580,571,887,420,834,2064,2067,165 | 1.278261105136215,-0.34522033918629164,-0.43578144422450665,-0.5084980423896142,-0.6180267920736977,3.264732786733322,3.9336836738560215,0.645370002187069,0.031208258927758886,0.11992981356626614,2.37041584169695,-0.7097240200629163,0.031208258927758886,0.8352060194424157,-0.4176396446871264,1.057703597794576,1.057703597794576,-0.004375775863415211,0.8007988770829282,0.4715023827975977,1.0406581721072192,0.5237938951093771,-0.25502527446770934,-0.25502527446770934,1.780200641127462 | 3,477 |
Nuclear membrane | 59 | 119 | 2.743924 | 0.006071 | Q96PE3,Q9BZF3,Q99523,Q15154,O60318,O75608,Q9NZJ0,Q96EB6,P20700,Q5BJF2,Q9H1E5,O76062,P50402,P02545,P49790,O00165,P49792,P62995,Q9H8M7,Q9H4L5,P12270,Q12765,Q86UE4,P37198,Q5SNT2,Q14728,Q5UIP0,Q9UIS9,P67809,Q9BVL2,Q9BZF1,Q96KC8,Q9Y2U8,O15504,Q9NUL3,Q6NUM9,P43243,O95619,Q86WB0,Q8N1F7,O14681,Q96RT1,Q9BTX1,Q13185,Q9UPP1,Q9BVI4,Q99720,Q9H2V7,P57740,Q96T37,Q5XPI4,Q9Y3D9,Q03252,Q7Z3B4,Q8IWB1,Q9UH99,O75844,P52948,Q15007 | Localization | GO Cellular component | msigdb_gocc | 1034,7,394,405,642,519,801,547,159,540,290,916,918,534,815,166,816,179,702,180,939,56,695,189,945,63,947,978,444,594,850,849,475,584,995,340,465,463,730,352,596,866,484,984,100,748,105,369,617,1015,243,894,490,1013,375,249,122,760,383 | 166,3324,1966,2657,596,2417,584,2308,642,1499,519,1885,122,916,1471,463,1888,534,3426,3427,2342,2140,939,3115,3243,159,1144,189,2725,3303,465,2848,815,816,3384,918,760,1123,617,2771,179,444,2593,490,56,984,63,1304,2892,383,405,2431,540,2676,1126,945,947,243,340,1980,1908,1013,2435,695,730,375,1670,2747,352,1796,2015,1031,1672,1365,1131,2402,1412,547,849,1034,866,1076,1015,394,1833,105,2502,484,3152,748,594,1729,1136,2938,850,7,290,369,180,702,1440,995,1529,1839,801,1991,2334,2374,249,978,2444,1599,3110,1963,100,475,894,2682,1255 | 1.7636218040365772,-1.419961736541305,-0.2190483838022552,-0.6180267920736977,0.7663438381457375,-0.4539381330689716,0.7835773618879034,-0.39951268421354885,0.7145708685502362,0.031208258927758886,0.8523917149803377,-0.18312871527243837,1.978355565936782,0.43657813874424445,0.0489797444034831,0.938142788391448,-0.18312871527243837,0.8352060194424157,-1.9012348366427068,-1.9012348366427068,-0.4176396446871264,-0.30909872995436094,0.4190969319876285,-1.0244693677889274,-1.230677582860357,1.780200641127462,0.26118655325487,1.6805731451820296,-0.6546590794968076,-1.3629900695977135,0.938142788391448,-0.7649300864530652,0.541199255452286,0.541199255452286,-1.6302629358411647,0.43657813874424445,0.5933404260508179,0.27878413552863,0.7490982712358505,-0.6913534327057209,1.7138236090436918,0.972361052266646,-0.5631937933047674,0.9038777056804731,2.6126927177320334,0.3840961570394507,2.4998877799465182,0.17300089051442,-0.8018132756130776,1.0917600484003518,1.057703597794576,-0.4539381330689716,0.8352060194424157,-0.6180267920736977,0.27878413552863,0.4190969319876285,0.4190969319876285,1.446643388062751,1.1936564655011561,-0.2190483838022552,-0.18312871527243837,0.3665765114452106,-0.4539381330689716,0.6626885650713121,0.6280391487957254,1.125770842652169,-0.057855143918590056,-0.6729984707451497,1.1767019777664645,-0.1293556878583202,-0.23702965284823038,0.34904397515841284,-0.057855143918590056,0.13763357601742993,0.27878413552863,-0.43578144422450665,0.10221259161251053,0.8352060194424157,0.5063759878506557,0.34904397515841284,0.4889454962781681,0.31394007341810976,0.3665765114452106,1.0747375459534367,-0.1472658952589451,2.093282645393226,-0.49029638115367696,0.9210161159169525,-1.061809293070439,0.6106959688336498,0.7835773618879034,-0.09357744939710187,0.27878413552863,-0.8387603079978073,0.5063759878506557,4.573593931116834,1.295148685478845,1.1427591973209943,1.7138236090436918,0.6626885650713121,0.08448186784031635,0.3840961570394507,0.031208258927758886,-0.1472658952589451,0.5585921060824289,-0.2190483838022552,-0.39951268421354885,-0.4176396446871264,1.4298541607079167,0.4016029509522354,-0.4539381330689716,-0.004375775863415211,-1.005824441947442,-0.20108142022241898,2.1260307366165443,0.938142788391448,0.4715023827975977,-0.6180267920736977,0.20831486901201274 | 3,477 |
Molecular transducer activity | 12 | 34 | 2.743585 | 0.006077 | Q04721,O15173,Q99523,Q9Y6I9,Q14108,P30536,P04150,Q99720,O15118,Q8WTV0,Q4VCS5,Q15629 | Functions | GO Molecular function | msigdb_gomf | 446,196,394,41,330,43,389,105,553,19,604,116 | 553,196,613,389,1687,2480,857,1265,43,1507,2143,2932,1049,446,2594,1664,2537,330,2045,116,2251,604,19,2360,2058,394,105,3123,2157,2304,872,3109,1289,41 | 0.8180084181768476,1.630619414996261,0.7490982712358505,1.0747375459534367,-0.07570932756690205,-0.49029638115367696,0.4889454962781681,0.19066452603648326,2.7890650119210334,0.031208258927758886,-0.30909872995436094,-0.8387603079978073,0.3314985089593542,0.972361052266646,-0.5631937933047674,-0.057855143918590056,-0.5267147969292446,1.2105997259678525,-0.25502527446770934,2.0112411668915997,-0.36330308096834,0.7663438381457375,3.4997508506844,-0.4176396446871264,-0.25502527446770934,1.0747375459534367,2.093282645393226,-1.0244693677889274,-0.30909872995436094,-0.38140051285772825,0.4889454962781681,-1.005824441947442,0.19066452603648326,2.9166640395548185 | 3,477 |
Organelle inner membrane | 55 | 258 | 2.72972 | 0.006339 | Q99595,O75964,O60830,O43676,P06576,P22830,P00846,Q16134,Q9P0J0,Q9BQT8,Q9Y2R0,O95831,Q13505,P13073,Q567V2,Q9H9P8,Q9Y2Z9,P20700,Q10713,Q13423,Q9H1E5,Q9Y619,Q8N183,Q69YU5,P14927,P22695,P62995,Q9Y5Y0,Q14728,Q9H061,Q9UJS0,P23786,Q9Y2U8,P43243,P53701,Q8IYU8,O96000,Q9BSK2,Q96NB2,O43772,O75489,P36551,Q70HW3,Q16540,O95169,Q99720,Q9H2V7,P14406,Q9NX63,Q9UDX5,Q03252,Q9Y512,Q6DKK2,Q9UH99,O75844 | Localization | GO Cellular component | msigdb_gocc | 1,257,4,133,262,9,10,266,409,18,23,24,276,400,416,420,30,159,286,161,290,165,168,42,171,298,179,188,63,320,322,78,475,465,90,351,464,353,95,97,477,356,229,103,104,105,369,109,241,112,490,504,117,249,122 | 2229,1005,659,1879,598,1160,133,3425,97,1810,1291,757,4,837,3054,1997,1683,2198,708,1260,477,856,1023,809,122,1198,740,257,1849,916,1471,983,104,3448,1998,2100,1451,1887,24,464,1117,2788,10,1542,3438,1659,2789,262,3416,917,1891,2071,2808,2343,1264,1816,2617,2885,400,109,3010,171,2275,1570,2074,724,2887,1168,159,1818,3270,298,9,1896,78,1143,1404,3363,3191,2107,2423,2170,1971,356,2949,3401,1605,2725,465,1575,2513,3346,3460,3230,1973,918,2766,1007,1477,2950,90,2204,3285,1123,919,2771,179,1752,742,942,1355,2772,2246,2426,3071,761,2041,1009,490,286,1790,2463,984,1612,161,276,1938,63,1304,539,266,103,2731,2357,728,589,1828,416,1126,945,2955,713,42,117,1648,2832,744,3021,886,2086,229,2971,845,3150,1586,1670,351,168,1697,1722,3398,2817,2292,2015,1437,1650,1587,3348,1281,1830,1214,1215,1871,848,3104,547,2916,1250,1592,1312,95,1724,1,2153,105,1134,1593,18,1439,1950,353,2502,3089,2364,3161,2189,2124,1558,2751,1913,1415,320,290,852,369,2438,2155,1773,1838,2441,420,1395,1956,3138,2503,1526,518,1775,2874,2127,832,2753,1561,1193,1112,241,1628,2266,783,409,672,1113,112,1531,249,322,1491,2681,2132,2267,23,3112,2066,475,30,658,3252,1921,2606,894,1235,504,2336,188,165,895,1372,936 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| 3,477 |
Positive regulation of mrna processing | 10 | 22 | 2.726474 | 0.006402 | P98179,Q14011,Q9Y2W1,Q96EP5,Q96E39,P62995,Q8N7H5,P38159,Q15427,Q13595 | Processes and pathways | GO Biological process | msigdb_gobp | 34,35,398,494,206,179,469,55,620,287 | 1258,2139,2844,644,3228,55,1607,760,179,34,1643,920,287,35,620,1389,469,206,494,1676,2476,398 | 0.19066452603648326,-0.30909872995436094,-0.7649300864530652,0.7145708685502362,-1.2118458207692089,2.6126927177320334,-0.02218841243594591,0.5933404260508179,1.7138236090436918,3.1070264246639914,-0.04001485370627771,0.43657813874424445,1.295148685478845,3.1070264246639914,0.7490982712358505,0.11992981356626614,0.938142788391448,1.6139472546177651,0.9038777056804731,-0.057855143918590056,-0.4721097617635663,1.0747375459534367 | 3,477 |
Protein import | 32 | 85 | 2.69837 | 0.006968 | Q99595,O60830,P35658,Q9NS69,Q13501,Q13148,O95831,O14925,P02545,P49790,Q9UKG1,P49792,P31749,P37198,Q92973,Q15717,Q99567,Q9BVL2,O75381,Q7Z4Q2,Q3ZCQ8,Q14978,P52292,O43615,Q8N1F7,O75312,P56589,O14737,P57740,Q9Y512,P40855,P52948 | Processes and pathways | GO Biological process | msigdb_gobp | 1,4,646,15,403,402,24,659,534,815,564,816,183,189,829,827,461,594,197,591,589,712,710,598,352,599,239,487,617,504,246,760 | 2269,2837,2657,487,659,2759,598,4,599,197,1885,1850,2554,2163,1094,24,1117,534,1815,2643,2644,2645,1264,2844,939,2618,2558,2721,183,3078,646,189,1507,246,815,816,710,2315,760,2515,239,617,2771,3264,3356,1610,3016,1512,402,2208,403,2892,712,1755,2542,827,2252,589,2324,1013,844,591,352,2053,1365,829,1653,1674,461,1,2153,594,1729,2062,1395,1525,15,2020,2922,2941,564,1599,1842,504,1495 | -0.38140051285772825,-0.7649300864530652,-0.6180267920736977,0.9038777056804731,0.6972889626491571,-0.6913534327057209,0.7663438381457375,4.61882102015611,0.7663438381457375,1.630619414996261,-0.18312871527243837,-0.16519022238487766,-0.5449466965406411,-0.3271522384422823,0.2963686288929385,3.264732786733322,0.27878413552863,0.8352060194424157,-0.1472658952589451,-0.5997337881958207,-0.5997337881958207,-0.5997337881958207,0.19066452603648326,-0.7649300864530652,0.4190969319876285,-0.5814561396181898,-0.5449466965406411,-0.6546590794968076,1.6972035615388537,-0.9871961254841282,0.7145708685502362,1.6805731451820296,0.031208258927758886,1.4298541607079167,0.541199255452286,0.541199255452286,0.645370002187069,-0.39951268421354885,0.5933404260508179,-0.5084980423896142,1.463421832352514,0.7490982712358505,-0.6913534327057209,-1.2495267166562185,-1.5343945023334924,-0.02218841243594591,-0.9128477418208648,0.031208258927758886,1.057703597794576,-0.34522033918629164,1.057703597794576,-0.8018132756130776,0.645370002187069,-0.11145955440898236,-0.5267147969292446,0.5237938951093771,-0.36330308096834,0.7835773618879034,-0.39951268421354885,0.3665765114452106,0.5063759878506557,0.7835773618879034,1.1767019777664645,-0.25502527446770934,0.13763357601742993,0.5237938951093771,-0.04001485370627771,-0.057855143918590056,0.9552577561979099,5.037989622421626,-0.30909872995436094,0.7835773618879034,-0.09357744939710187,-0.25502527446770934,0.11992981356626614,0.031208258927758886,3.6398950642313137,-0.23702965284823038,-0.8202787828880227,-0.8387603079978073,0.8180084181768476,-0.004375775863415211,-0.1472658952589451,0.8867275244232448,0.0489797444034831 | 3,477 |
Negative regulation of rna splicing | 7 | 18 | 2.688218 | 0.007183 | Q13242,O75494,Q07021,P38159,P98175,P22626,P61978 | Processes and pathways | GO Biological process | msigdb_gobp | 233,324,301,55,275,155,252 | 1090,324,155,1572,2000,55,252,3305,275,301,2179,2043,233,1174,923,359,2501,1562 | 0.2963686288929385,1.2105997259678525,1.796769241269738,-0.004375775863415211,-0.23702965284823038,2.6126927177320334,1.4130541216407417,-1.3629900695977135,1.328890738532374,1.2613624491146502,-0.3271522384422823,-0.25502527446770934,1.480189522091329,0.24357584178456979,0.43657813874424445,1.1597362320078495,-0.49029638115367696,0.013423100007657314 | 3,477 |
Peroxisome | 14 | 33 | 2.684416 | 0.007266 | O00116,Q13011,O75521,O15228,O75381,Q15067,P48735,P56589,O14734,Q9NR77,Q9BQG2,Q9BY49,P40855,P34913 | Processes and pathways | KEGG Pathways | msigdb_kegg | 421,102,167,388,197,172,327,239,271,273,50,285,246,29 | 421,271,388,476,1349,2070,197,167,1140,1851,3030,2924,3257,1745,2314,3429,1746,29,2171,3401,246,327,2281,239,3170,102,172,2913,2150,50,285,273,704 | 1.0236012369190428,1.3457452705931343,1.0747375459534367,0.9210161159169525,0.13763357601742993,-0.2730352960413805,1.630619414996261,1.7636218040365772,0.26118655325487,-0.16519022238487766,-0.9314102255969627,-0.8387603079978073,-1.2495267166562185,-0.11145955440898236,-0.39951268421354885,-1.9012348366427068,-0.11145955440898236,3.217508323661947,-0.3271522384422823,-1.7459284461455995,1.4298541607079167,1.2105997259678525,-0.38140051285772825,1.463421832352514,-1.0992163962621977,2.1096615598283077,1.747032703853092,-0.8202787828880227,-0.30909872995436094,2.644840990732748,1.3120252200291715,1.3457452705931343,0.6626885650713121 | 3,477 |
Apoptosis | 35 | 138 | 2.680659 | 0.007348 | P21796,O75940,Q9UHX1,P46379,Q8N163,Q03164,P04150,Q9P0J0,Q13501,O95831,Q96EB6,Q9BXK5,Q9HB09,Q53EL6,Q07021,P61289,Q9ULW0,P31749,Q14728,P31751,Q9NR28,Q9Y3D6,P09601,Q01085,Q9UER7,Q96IZ0,O14681,P52756,Q13546,Q9UDX5,O14737,P42575,Q9H2J4,P05067,P05771 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 128,3,260,508,139,649,389,409,403,24,547,297,426,432,301,555,442,183,63,192,71,346,212,339,612,221,596,227,479,112,487,616,639,124,127 | 756,1256,1040,596,487,2553,807,1703,757,878,1568,2641,3,1704,1658,1024,1094,24,1352,389,3426,1815,124,127,2643,212,2617,2904,128,1896,2037,1933,3413,183,192,2488,616,2847,508,1097,3205,2766,1298,227,1299,555,2493,3248,3449,1640,1609,1753,339,649,1610,301,1432,1099,3017,2796,1936,1512,2853,1976,1358,906,403,479,2498,2210,2466,762,1454,63,3403,2045,1455,2252,432,2831,1012,2084,1793,1669,1696,2009,1181,1586,139,1437,2259,1799,1620,2546,3406,1284,547,668,1945,926,2654,221,1946,974,990,1035,1220,1803,297,2937,1771,2833,1954,639,2155,702,426,1732,2548,71,2157,2158,1466,409,977,112,612,260,1087,442,1992,914,3431,1401,346,1680,935,1448 | 0.5933404260508179,0.19066452603648326,0.3314985089593542,0.7663438381457375,0.9038777056804731,-0.5449466965406411,0.541199255452286,-0.09357744939710187,0.5933404260508179,0.4715023827975977,-0.004375775863415211,-0.5997337881958207,4.648937862838768,-0.09357744939710187,-0.057855143918590056,0.34904397515841284,0.2963686288929385,3.264732786733322,0.13763357601742993,1.0747375459534367,-1.9012348366427068,-0.1472658952589451,1.9618978796135385,1.9124649794523898,-0.5997337881958207,1.580571395190101,-0.5814561396181898,-0.8202787828880227,1.9124649794523898,-0.18312871527243837,-0.25502527446770934,-0.20108142022241898,-1.8234243897747608,1.6972035615388537,1.6472810988328224,-0.49029638115367696,0.7490982712358505,-0.7649300864530652,0.8695655387205098,0.2963686288929385,-1.1554541083078504,-0.6913534327057209,0.17300089051442,1.5136927513121756,0.17300089051442,0.8180084181768476,-0.49029638115367696,-1.230677582860357,-2.176126586591169,-0.04001485370627771,-0.02218841243594591,-0.11145955440898236,1.1936564655011561,0.7145708685502362,-0.02218841243594591,1.2613624491146502,0.08448186784031635,0.2963686288929385,-0.9128477418208648,-0.7097240200629163,-0.20108142022241898,0.031208258927758886,-0.7649300864530652,-0.2190483838022552,0.13763357601742993,0.4540466096167885,1.057703597794576,0.9210161159169525,-0.49029638115367696,-0.34522033918629164,-0.4721097617635663,0.5933404260508179,0.06673759969946712,2.4998877799465182,-1.7459284461455995,-0.25502527446770934,0.06673759969946712,-0.36330308096834,1.0065327601008498,-0.746512291400033,0.3665765114452106,-0.2730352960413805,-0.1293556878583202,-0.057855143918590056,-0.07570932756690205,-0.23702965284823038,0.24357584178456979,-0.004375775863415211,1.8629417911591617,0.08448186784031635,-0.36330308096834,-0.1293556878583202,-0.02218841243594591,-0.5267147969292446,-1.765273233178852,0.19066452603648326,0.8352060194424157,0.6972889626491571,-0.20108142022241898,0.43657813874424445,-0.5997337881958207,1.547153301208781,-0.20108142022241898,0.4016029509522354,0.3840961570394507,0.34904397515841284,0.22595196061218203,-0.1293556878583202,1.278261105136215,-0.8387603079978073,-0.11145955440898236,-0.746512291400033,-0.20108142022241898,0.7318406263618454,-0.30909872995436094,0.6626885650713121,1.0236012369190428,-0.09357744939710187,-0.5267147969292446,2.419037471494315,-0.30909872995436094,-0.30909872995436094,0.06673759969946712,1.057703597794576,0.4016029509522354,2.0276691307788863,0.7663438381457375,1.3962432420799271,0.31394007341810976,0.9894527093654699,-0.2190483838022552,0.4540466096167885,-1.9012348366427068,0.11992981356626614,1.1936564655011561,-0.057855143918590056,0.43657813874424445,0.08448186784031635 | 3,477 |
Nuclear envelope organization | 12 | 33 | 2.680091 | 0.00736 | Q8IXJ6,Q9ULX6,Q9H444,Q9Y2U8,Q86XL3,Q13148,Q9HD42,Q9UH99,O75844,P05771,Q8N1F7,P20700 | Processes and pathways | GO Biological process | msigdb_gobp | 6,140,306,475,147,402,187,249,122,127,352,159 | 3296,1885,122,1471,534,127,3243,159,3303,918,2079,402,1580,1126,147,6,352,2015,1213,3210,2405,2502,306,1465,187,997,249,140,2602,754,1809,475,935 | -1.3440352974719634,-0.18312871527243837,1.978355565936782,0.0489797444034831,0.8352060194424157,1.9124649794523898,-1.230677582860357,1.780200641127462,-1.3629900695977135,0.43657813874424445,-0.2730352960413805,1.057703597794576,-0.004375775863415211,0.27878413552863,1.829875834701021,4.573593931116834,1.1767019777664645,-0.23702965284823038,0.22595196061218203,-1.1554541083078504,-0.43578144422450665,-0.49029638115367696,1.2613624491146502,0.06673759969946712,1.6972035615388537,0.3840961570394507,1.4298541607079167,1.8629417911591617,-0.5631937933047674,0.6106959688336498,-0.1293556878583202,0.938142788391448,0.43657813874424445 | 3,477 |
Rna splicing via transesterification reactions | 81 | 191 | 2.677199 | 0.007424 | O75940,Q86V81,P98179,Q14011,O75400,Q92841,P38159,Q96PK6,P31942,Q96I25,P23246,P52272,P55081,P52597,P62312,Q15427,P31943,P51116,P19338,Q8IY67,O60828,P22626,Q9Y2W2,Q15459,O95391,P62310,P62995,O75475,Q16637,Q96E39,P78332,O75525,Q01130,Q92945,Q86UA1,P51114,Q15637,P52756,Q13242,Q9BWF3,Q96DF8,P51991,O95400,Q07666,P61978,P52948,O60506,Q07955,Q9UHX1,O43390,Q13123,Q9UBB9,P98175,Q13595,P09651,Q96PU8,O75934,Q07021,Q9Y3B4,Q96RS0,Q99590,Q15020,Q06787,O60508,O75494,Q12874,Q9P013,Q8WXF0,Q8WWY3,Q92917,P38432,O43290,Q15007,Q9Y2W1,Q14562,P07910,Q96MU7,Q6NZY4,Q13573,Q96EP5,O00566 | Processes and pathways | GO Biological process | msigdb_gobp | 3,544,34,35,532,561,55,579,59,578,569,587,80,94,618,620,115,631,644,667,661,155,687,675,175,178,179,689,194,206,209,211,213,225,729,223,726,227,233,749,746,237,236,253,252,760,256,258,260,264,272,274,275,287,812,304,810,301,835,830,831,826,824,323,324,840,345,359,888,889,361,877,383,398,907,900,927,924,920,494,486 | 3052,1090,486,2898,1469,877,264,1682,3325,2308,1022,2270,2661,2760,256,323,661,532,689,324,211,1261,2380,810,3,2840,3009,175,236,3268,900,2033,2139,1968,1427,812,1263,2844,1688,1660,1200,1096,2141,644,155,569,1572,2000,3228,59,115,55,361,2424,2619,1322,1121,223,631,237,587,1607,94,227,760,1509,80,3034,2535,252,2692,178,618,3387,3451,3417,179,209,2495,2593,1098,275,34,3157,213,824,301,253,258,2179,1642,1643,2043,840,272,233,1050,1174,1245,2854,920,287,2773,2517,35,2743,1692,907,383,826,2286,3149,620,2046,675,726,923,194,1360,1693,2519,1906,924,3060,2545,1456,969,729,544,3160,667,3299,2818,888,1619,359,3061,1153,561,889,225,1985,2735,746,2957,206,494,578,927,579,304,830,1947,1015,1725,831,2501,2470,2803,749,2781,3250,2820,1595,2752,2302,2919,1314,2020,345,274,1287,260,1490,3139,1562,1288,2476,1420,3075,398,687,1633,3447,2414,835,2605,2859,1058,3309,2337 | 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| 3,477 |
Circulatory system process | 15 | 78 | 2.665725 | 0.007682 | P08183,O75844,P0DP25,Q99808,P42892,P30825,Q9HB40,Q16625,P53985,Q9UIQ6,P09601,P00813,P33527,P42785,Q9NZ08 | Processes and pathways | GO Biological process | msigdb_gobp | 33,122,231,40,11,75,173,204,238,81,212,58,123,93,126 | 896,1059,2376,1197,1092,1376,1885,613,122,3334,1377,3067,58,1686,2924,2101,1742,1932,33,212,231,2616,709,3055,2618,2886,901,3178,2313,2558,3223,2686,2240,75,123,294,2039,2144,93,11,1637,1689,1662,1172,2671,238,1787,2648,3469,1145,3197,2620,3444,1408,1857,1713,1904,906,3287,2004,1125,2287,2251,204,2005,3021,3045,3046,516,40,1523,2061,173,126,1231,81,2193,1536 | 0.4540466096167885,0.31394007341810976,-0.43578144422450665,0.22595196061218203,0.2963686288929385,0.11992981356626614,-0.18312871527243837,0.7490982712358505,1.978355565936782,-1.4389883090290831,0.11992981356626614,-0.9685843575272131,2.596605026352921,-0.07570932756690205,-0.8387603079978073,-0.29105976522553345,-0.11145955440898236,-0.20108142022241898,3.1544260335844876,1.580571395190101,1.496946485661057,-0.5814561396181898,0.645370002187069,-0.9499890775959331,-0.5814561396181898,-0.8018132756130776,0.4540466096167885,-1.1179452960132723,-0.39951268421354885,-0.5449466965406411,-1.1930313645227653,-0.6363352046117817,-0.36330308096834,2.37041584169695,1.978355565936782,1.278261105136215,-0.25502527446770934,-0.30909872995436094,2.1750800789820577,3.9028885923934347,-0.04001485370627771,-0.07570932756690205,-0.057855143918590056,0.24357584178456979,-0.6180267920736977,1.463421832352514,-0.1293556878583202,-0.5997337881958207,-4.43874782781883,0.26118655325487,-1.1366911787908272,-0.5814561396181898,-2.0971723037928203,0.10221259161251053,-0.16519022238487766,-0.09357744939710187,-0.18312871527243837,0.4540466096167885,-1.3061790135246543,-0.23702965284823038,0.27878413552863,-0.38140051285772825,-0.36330308096834,1.6139472546177651,-0.23702965284823038,-0.9128477418208648,-0.9314102255969627,-0.9314102255969627,0.8695655387205098,2.932574742931529,0.031208258927758886,-0.25502527446770934,1.747032703853092,1.9289526113250501,0.22595196061218203,2.289192128383176,-0.3271522384422823,0.031208258927758886 | 3,477 |
RNA splicing factor | 39 | 86 | 2.656294 | 0.0079 | Q07955,O75940,Q9UHX1,Q9UBB9,Q9P2K5,Q8IXT5,Q15459,O95391,Q96PU8,P62310,O75934,Q52LJ0,Q8IWZ8,Q9Y3B4,Q96PK6,P31942,Q96I25,Q15020,Q16637,O60508,P52272,O75494,Q12874,O75525,Q01130,Q86UA1,P52597,Q15637,Q8WXF0,Q12849,Q13242,P55795,Q9BWF3,Q8WWY3,P62312,O95400,Q15427,P31943,Q07666 | Functions | Panther Protein class | panther_protein_class | 258,3,260,274,551,417,675,175,304,178,810,435,437,835,579,59,578,826,194,323,587,324,840,211,213,729,94,726,359,859,233,106,749,888,618,236,620,115,253 | 1469,1682,1022,1258,323,324,211,1261,810,3,2840,1472,175,236,3268,2033,2139,1968,1263,2141,59,115,2619,587,94,106,2692,178,618,3387,3417,1098,213,3396,253,258,2179,1643,859,2043,840,233,1050,1174,1245,920,2743,826,620,2046,675,726,923,194,435,3060,729,437,1585,417,1105,888,3087,359,889,578,579,304,2803,749,1802,2781,1772,2368,2919,2410,2020,551,274,260,3139,1633,3447,835,1058,3309 | 0.0489797444034831,-0.07570932756690205,0.34904397515841284,0.19066452603648326,1.2105997259678525,1.2105997259678525,1.580571395190101,0.19066452603648326,0.541199255452286,4.648937862838768,-0.7649300864530652,0.0489797444034831,1.730433314315435,1.463421832352514,-1.2683932884585893,-0.25502527446770934,-0.30909872995436094,-0.2190483838022552,0.19066452603648326,-0.30909872995436094,2.5805082703873468,2.0112411668915997,-0.5814561396181898,0.7835773618879034,2.1587399725073695,2.0768939693689594,-0.6363352046117817,1.7138236090436918,0.7490982712358505,-1.6494929110757173,-1.842847311166223,0.2963686288929385,1.580571395190101,-1.7266029911540117,1.4130541216407417,1.3962432420799271,-0.3271522384422823,-0.04001485370627771,0.4889454962781681,-0.25502527446770934,0.5063759878506557,1.480189522091329,0.3314985089593542,0.24357584178456979,0.20831486901201274,0.43657813874424445,-0.6729984707451497,0.5237938951093771,0.7490982712358505,-0.25502527446770934,0.6799948733270359,0.6280391487957254,0.43657813874424445,1.6472810988328224,0.9894527093654699,-0.9499890775959331,0.6280391487957254,0.9894527093654699,-0.004375775863415211,1.0406581721072192,0.2963686288929385,0.4715023827975977,-0.9871961254841282,1.1597362320078495,0.4715023827975977,0.8007988770829282,0.8007988770829282,1.2613624491146502,-0.7097240200629163,0.6106959688336498,-0.1293556878583202,-0.6913534327057209,-0.11145955440898236,-0.4176396446871264,-0.8202787828880227,-0.43578144422450665,-0.23702965284823038,0.8352060194424157,1.3457452705931343,1.3962432420799271,-1.0431309642750133,-0.02218841243594591,-2.1366073426776953,0.5237938951093771,0.3314985089593542,-1.3629900695977135 | 3,477 |
Smad protein signal transduction | 6 | 9 | 2.641971 | 0.008243 | P53999,P09874,O00400,P08670,Q9UIQ6,Q8N1F7 | Processes and pathways | GO Biological process | msigdb_gobp | 129,98,293,70,81,352 | 293,70,98,129,1325,1150,352,579,81 | 1.278261105136215,2.419037471494315,2.1260307366165443,1.9124649794523898,0.1553239210492891,0.26118655325487,1.1767019777664645,0.8007988770829282,2.289192128383176 | 3,477 |
Serine protease | 8 | 28 | 2.618833 | 0.008823 | Q9H3G5,P67812,Q9HB40,Q96AE4,Q96I24,P34913,P42785,Q92945 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 96,130,173,215,245,29,93,225 | 1780,3076,1743,3115,2723,29,2487,93,963,760,3119,252,130,2796,1207,3058,1279,543,1436,3062,225,215,245,1727,96,173,1840,2025 | -0.1293556878583202,-0.9871961254841282,-0.11145955440898236,-1.0244693677889274,-0.6546590794968076,3.217508323661947,-0.49029638115367696,2.1750800789820577,0.4016029509522354,0.5933404260508179,-1.0244693677889274,1.4130541216407417,1.8959673156390773,-0.7097240200629163,0.22595196061218203,-0.9499890775959331,0.19066452603648326,0.8352060194424157,0.08448186784031635,-0.9499890775959331,1.530428347164649,1.580571395190101,1.446643388062751,-0.09357744939710187,2.1587399725073695,1.747032703853092,-0.1472658952589451,-0.23702965284823038 | 3,477 |
Mitochondrion organization | 63 | 202 | 2.60956 | 0.009066 | Q99595,P21796,Q9Y375,O60830,Q9Y2S7,O43676,O60313,Q8N163,Q5JRX3,Q9NS69,Q9P0J0,Q13501,Q9Y2R0,O95831,Q96EY1,Q13505,Q10713,O14925,P55786,Q15070,Q04837,P02545,O95429,Q9NUQ9,Q8N183,Q69YU5,P30536,O00165,P27544,Q8IWA4,P31749,Q00059,Q9H061,Q99797,Q9Y4P1,Q5XKP0,O75431,Q3ZCQ8,P45880,Q9Y3D6,Q7KZI7,Q9NVT9,Q9NQG6,Q8N4H5,O96000,Q92830,O43615,Q9BSK2,Q16891,Q9UII2,P09874,O75489,P0DP25,O95169,P14406,Q9NX63,Q9UDX5,Q96EP0,O14737,Q5TC12,Q9Y512,Q6DKK2,Q7Z3C6 | Processes and pathways | GO Biological process | msigdb_gobp | 1,128,658,4,657,133,757,139,390,15,409,403,23,24,668,276,286,659,32,539,537,534,533,685,168,42,43,166,430,696,183,692,320,718,337,713,708,589,79,346,468,737,736,342,464,220,598,353,728,485,98,477,231,104,109,241,112,747,487,365,504,117,512 | 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| 3,477 |
Tetrapyrrole metabolic process | 7 | 19 | 2.605047 | 0.009186 | P30519,P22830,P30536,Q9Y5Y0,P09601,P33527,O00264 | Processes and pathways | GO Biological process | msigdb_gobp | 5,9,43,188,212,123,250 | 250,837,3269,2842,212,9,5,43,123,356,1973,2492,1986,1110,1775,3074,3025,485,188 | 1.4130541216407417,0.5063759878506557,-1.2683932884585893,-0.7649300864530652,1.580571395190101,4.209496500908907,4.573593931116834,2.7890650119210334,1.978355565936782,1.1597362320078495,-0.2190483838022552,-0.49029638115367696,-0.2190483838022552,0.2963686288929385,-0.11145955440898236,-0.9685843575272131,-0.9128477418208648,0.9210161159169525,1.6972035615388537 | 3,477 |
Abnormality of the supraorbital ridges | 7 | 24 | 2.586272 | 0.009702 | Q9UPP1,P51812,O75381,P56589,P38159,P40855,P98175 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 100,67,197,239,55,246,275 | 197,3030,1428,1201,2558,55,246,67,2175,239,275,2991,295,2729,1582,2212,1648,2799,2629,1282,3001,1842,100,769 | 1.630619414996261,-0.9314102255969627,0.08448186784031635,0.22595196061218203,-0.5449466965406411,2.6126927177320334,1.4298541607079167,2.435226048707906,-0.3271522384422823,1.463421832352514,1.328890738532374,-0.8943015669385899,1.278261105136215,-0.6546590794968076,-0.004375775863415211,-0.34522033918629164,-0.04001485370627771,-0.7097240200629163,-0.5814561396181898,0.19066452603648326,-0.8943015669385899,-0.1472658952589451,2.1260307366165443,0.5933404260508179 | 3,477 |
Signaling | 11 | 20 | 2.56744 | 0.010245 | O75475,O15173,Q9Y3E1,Q99627,Q13123,Q7Z4V5,P42166,Q8WUJ1,P51858,Q96PC5,O00264 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 689,196,74,470,272,559,615,21,151,378,250 | 250,2739,196,689,2074,615,787,151,1432,1099,272,1275,559,1869,21,974,378,470,2922,74 | 1.4130541216407417,-0.6729984707451497,1.630619414996261,0.6626885650713121,-0.2730352960413805,0.7490982712358505,0.5585921060824289,1.8133276304905637,0.08448186784031635,0.2963686288929385,1.3457452705931343,0.19066452603648326,0.8180084181768476,-0.16519022238487766,3.405962585151882,0.4016029509522354,1.125770842652169,0.938142788391448,-0.8202787828880227,2.3866323901235114 | 3,477 |
Porphyrin containing compound metabolic process | 8 | 17 | 2.558996 | 0.010497 | P36551,P30519,P22830,P30536,Q9Y5Y0,P09601,P33527,O00264 | Processes and pathways | GO Biological process | msigdb_gobp | 356,5,9,43,188,212,123,250 | 250,837,3269,2842,212,9,5,43,123,356,1973,2492,1775,3074,3025,485,188 | 1.4130541216407417,0.5063759878506557,-1.2683932884585893,-0.7649300864530652,1.580571395190101,4.209496500908907,4.573593931116834,2.7890650119210334,1.978355565936782,1.1597362320078495,-0.2190483838022552,-0.49029638115367696,-0.11145955440898236,-0.9685843575272131,-0.9128477418208648,0.9210161159169525,1.6972035615388537 | 3,477 |
Exopeptidase activity | 11 | 31 | 2.547953 | 0.010836 | P55786,Q9H3G5,O75844,Q9HB40,Q9UIQ6,P09960,P42785,Q12765,Q7Z2K6,O75976,Q9NZ08 | Functions | GO Molecular function | msigdb_gomf | 32,96,122,173,81,110,93,56,157,317,126 | 3076,122,317,1686,110,1743,3031,3093,2723,356,93,2742,2317,32,56,3385,157,1279,1984,2294,2362,3459,2120,96,3048,173,720,2126,3342,126,81 | -0.9871961254841282,1.978355565936782,1.2275317897751026,-0.07570932756690205,2.0276691307788863,-0.11145955440898236,-0.9314102255969627,-1.005824441947442,-0.6546590794968076,1.1597362320078495,2.1750800789820577,-0.6729984707451497,-0.39951268421354885,3.1702091254103086,2.6126927177320334,-1.6302629358411647,1.796769241269738,0.19066452603648326,-0.2190483838022552,-0.38140051285772825,-0.4176396446871264,-2.616618108965407,-0.29105976522553345,2.1587399725073695,-0.9314102255969627,1.747032703853092,0.645370002187069,-0.29105976522553345,-1.4389883090290831,1.9289526113250501,2.289192128383176 | 3,477 |
Positive regulation of rna splicing | 10 | 23 | 2.545535 | 0.010911 | P98179,Q14011,Q9Y2W1,O75312,Q96EP5,Q96E39,P62995,Q15427,P38159,Q13595 | Processes and pathways | GO Biological process | msigdb_gobp | 34,35,398,599,494,206,179,620,55,287 | 599,2139,2844,644,2722,1572,3228,55,760,179,34,1643,1050,920,287,35,620,1185,206,494,2020,2476,398 | 0.7663438381457375,-0.30909872995436094,-0.7649300864530652,0.7145708685502362,-0.6546590794968076,-0.004375775863415211,-1.2118458207692089,2.6126927177320334,0.5933404260508179,1.7138236090436918,3.1070264246639914,-0.04001485370627771,0.3314985089593542,0.43657813874424445,1.295148685478845,3.1070264246639914,0.7490982712358505,0.24357584178456979,1.6139472546177651,0.9038777056804731,-0.23702965284823038,-0.4721097617635663,1.0747375459534367 | 3,477 |
Atrophy degeneration involving the corticospinal tracts | 6 | 15 | 2.540577 | 0.011067 | O00400,P00846,P35637,Q13501,Q13148,Q12768 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 293,10,76,403,402,538 | 293,2196,2378,10,1380,76,2794,1510,538,402,403,1580,571,2064,2067 | 1.278261105136215,-0.34522033918629164,-0.43578144422450665,3.9336836738560215,0.11992981356626614,2.37041584169695,-0.7097240200629163,0.031208258927758886,0.8352060194424157,1.057703597794576,1.057703597794576,-0.004375775863415211,0.8007988770829282,-0.25502527446770934,-0.25502527446770934 | 3,477 |
Slc mediated transmembrane transport | 9 | 23 | 2.540186 | 0.011079 | O00400,Q70HW3,Q99808,Q15043,P30825,P53985,Q9UBX3,Q9H2J7,Q8NEW0 | Processes and pathways | Reactome Pathways | msigdb_reactome | 293,229,40,331,75,238,672,611,248 | 293,1706,2789,1707,709,1816,2617,2240,75,1604,2687,238,1787,331,2251,2005,229,248,1334,40,611,672,2193 | 1.278261105136215,-0.09357744939710187,-0.7097240200629163,-0.09357744939710187,0.645370002187069,-0.1472658952589451,-0.5814561396181898,-0.36330308096834,2.37041584169695,-0.02218841243594591,-0.6363352046117817,1.463421832352514,-0.1293556878583202,1.2105997259678525,-0.36330308096834,-0.23702965284823038,1.5136927513121756,1.4298541607079167,0.1553239210492891,2.932574742931529,0.7663438381457375,0.6972889626491571,-0.3271522384422823 | 3,477 |
Microbody | 17 | 56 | 2.521495 | 0.011686 | P08670,Q13011,O75521,O15228,O75381,Q15067,P48735,P56589,O14734,Q5T8D3,Q9NR77,Q9BQG2,Q9Y3D6,Q9BY49,P40855,P34913,Q8N4Q0 | Localization | GO Cellular component | msigdb_gocc | 70,102,167,388,197,172,327,239,271,364,273,50,346,285,246,29,191 | 421,896,271,388,476,1349,2070,197,167,1140,1851,3030,741,70,3257,1893,1353,1745,2314,3393,3429,1746,29,2171,3401,246,327,883,2281,2316,1549,239,3170,102,2728,3397,172,2913,364,2255,2049,2086,844,191,1333,2150,1764,1768,50,285,736,273,3107,704,346,3323 | 1.0236012369190428,0.4540466096167885,1.3457452705931343,1.0747375459534367,0.9210161159169525,0.13763357601742993,-0.2730352960413805,1.630619414996261,1.7636218040365772,0.26118655325487,-0.16519022238487766,-0.9314102255969627,0.6106959688336498,2.419037471494315,-1.2495267166562185,-0.18312871527243837,0.13763357601742993,-0.11145955440898236,-0.39951268421354885,-1.7266029911540117,-1.9012348366427068,-0.11145955440898236,3.217508323661947,-0.3271522384422823,-1.7459284461455995,1.4298541607079167,1.2105997259678525,0.4715023827975977,-0.38140051285772825,-0.39951268421354885,0.013423100007657314,1.463421832352514,-1.0992163962621977,2.1096615598283077,-0.6546590794968076,-1.7266029911540117,1.747032703853092,-0.8202787828880227,1.1427591973209943,-0.36330308096834,-0.25502527446770934,-0.2730352960413805,0.5063759878506557,1.663932333233678,0.1553239210492891,-0.30909872995436094,-0.11145955440898236,-0.11145955440898236,2.644840990732748,1.3120252200291715,0.6280391487957254,1.3457452705931343,-1.005824441947442,0.6626885650713121,1.1936564655011561,-1.400953219377142 | 3,477 |
Ion transmembrane transport | 35 | 165 | 2.512926 | 0.011973 | P21796,O75964,P06576,P00846,Q96ES6,Q9UHG3,Q9BQT8,P13073,P08183,Q13423,Q9Y619,P41440,O00400,Q8IWX8,P46934,Q14728,Q9UJS0,Q9C0H2,Q15043,P30825,P45880,Q9Y277,Q9HD20,P98194,Q8IYU8,Q96NB2,O43772,Q70HW3,Q13546,P0DP25,P53985,Q8NEW0,O75844,P33527,P05067 | Processes and pathways | GO Biological process | msigdb_gobp | 128,257,262,10,392,13,18,400,33,161,165,294,293,423,62,63,322,335,331,75,79,474,216,466,351,95,97,229,479,231,238,248,122,123,124 | 3324,293,2229,1005,2376,1197,1257,97,1349,1498,2587,1740,837,3163,3054,2028,1260,809,122,2612,740,257,1998,1451,2788,10,3438,1706,1742,124,2789,1687,262,2201,2901,917,2235,33,1707,1891,2884,231,2343,2481,1816,2617,400,3010,901,3178,1635,2313,1168,1266,3180,2558,128,3223,1143,1404,3428,2686,3413,2240,75,2107,123,903,3181,1971,941,1972,294,2847,79,62,1636,2513,2109,759,3365,2950,238,2567,3246,1787,1123,919,1382,3184,1145,1065,2620,466,2041,1753,1009,1641,824,1432,1858,1666,161,479,3287,1905,2729,63,1581,3403,331,1791,2251,1068,744,2970,2777,229,2630,423,351,3045,733,2089,1650,248,1334,1281,2360,392,2654,95,516,3266,2153,1523,1134,18,3152,1484,335,1837,852,611,2061,1838,1956,216,2303,1085,672,1113,2922,13,1017,322,1491,1735,474,2193,2945,3126,1235,165,3415 | -1.419961736541305,1.278261105136215,-0.36330308096834,0.3665765114452106,-0.43578144422450665,0.22595196061218203,0.19066452603648326,2.1423901995972563,0.13763357601742993,0.031208258927758886,-0.5631937933047674,-0.11145955440898236,0.5063759878506557,-1.0992163962621977,-0.9499890775959331,-0.25502527446770934,0.19066452603648326,0.541199255452286,1.978355565936782,-0.5814561396181898,0.6106959688336498,1.3962432420799271,-0.23702965284823038,0.06673759969946712,-0.7097240200629163,3.9336836738560215,-1.959802266913443,-0.09357744939710187,-0.11145955440898236,1.9618978796135385,-0.7097240200629163,-0.07570932756690205,1.3794214931092326,-0.34522033918629164,-0.8202787828880227,0.43657813874424445,-0.36330308096834,3.1544260335844876,-0.09357744939710187,-0.18312871527243837,-0.8018132756130776,1.496946485661057,-0.4176396446871264,-0.49029638115367696,-0.1472658952589451,-0.5814561396181898,1.057703597794576,-0.9128477418208648,0.4540466096167885,-1.1179452960132723,-0.04001485370627771,-0.39951268421354885,0.24357584178456979,0.19066452603648326,-1.1179452960132723,-0.5449466965406411,1.9124649794523898,-1.1930313645227653,0.26118655325487,0.10221259161251053,-1.9012348366427068,-0.6363352046117817,-1.8234243897747608,-0.36330308096834,2.37041584169695,-0.29105976522553345,1.978355565936782,0.4540466096167885,-1.1179452960132723,-0.2190483838022552,0.4190969319876285,-0.2190483838022552,1.278261105136215,-0.7649300864530652,2.3379546179921205,2.4998877799465182,-0.04001485370627771,-0.5084980423896142,-0.29105976522553345,0.5933404260508179,-1.5726858889559527,-0.8572579084205912,1.463421832352514,-0.5449466965406411,-1.230677582860357,-0.1293556878583202,0.27878413552863,0.43657813874424445,0.11992981356626614,-1.1179452960132723,0.26118655325487,0.31394007341810976,-0.5814561396181898,0.938142788391448,-0.25502527446770934,-0.11145955440898236,0.3665765114452106,-0.04001485370627771,0.5237938951093771,0.08448186784031635,-0.16519022238487766,-0.057855143918590056,1.780200641127462,0.9210161159169525,-1.3061790135246543,-0.18312871527243837,-0.6546590794968076,2.4998877799465182,-0.004375775863415211,-1.7459284461455995,1.2105997259678525,-0.1293556878583202,-0.36330308096834,0.31394007341810976,0.6106959688336498,-0.8757716419980323,-0.6913534327057209,1.5136927513121756,-0.5814561396181898,1.0236012369190428,1.1767019777664645,-0.9314102255969627,0.6280391487957254,-0.2730352960413805,-0.04001485370627771,1.4298541607079167,0.1553239210492891,0.19066452603648326,-0.4176396446871264,1.0747375459534367,-0.5997337881958207,2.1587399725073695,0.8695655387205098,-1.2495267166562185,-0.30909872995436094,0.031208258927758886,0.27878413552863,3.5153541654854648,-1.061809293070439,0.0489797444034831,1.2105997259678525,-0.1472658952589451,0.5063759878506557,0.7663438381457375,-0.25502527446770934,-0.1472658952589451,-0.20108142022241898,1.580571395190101,-0.38140051285772825,0.31394007341810976,0.6972889626491571,0.2963686288929385,-0.8202787828880227,3.76393416406384,0.3665765114452106,1.2275317897751026,0.0489797444034831,-0.09357744939710187,0.938142788391448,-0.3271522384422823,-0.8387603079978073,-1.0244693677889274,0.22595196061218203,1.780200641127462,-1.8234243897747608 | 3,477 |
Intermediate filament, rod domain [IPR039008] | 6 | 7 | 2.50875 | 0.012116 | P08670,Q16352,P48681,Q03252,P07197,P20700 | Sequence | InterPro Domain | interpro_domain | 70,457,456,490,182,159 | 534,182,70,159,456,490,457 | 0.8352060194424157,1.6972035615388537,2.419037471494315,1.780200641127462,0.9552577561979099,0.9038777056804731,0.9552577561979099 | 3,477 |
Intermediate filament protein, conserved site [IPR018039] | 6 | 7 | 2.50875 | 0.012116 | P08670,Q16352,P48681,Q03252,P07197,P20700 | Sequence | InterPro Conserved site | interpro_conserved_site | 70,457,456,490,182,159 | 534,182,70,159,456,490,457 | 0.8352060194424157,1.6972035615388537,2.419037471494315,1.780200641127462,0.9552577561979099,0.9038777056804731,0.9552577561979099 | 3,477 |
Contractures of the joints of the upper limbs | 19 | 73 | 2.508287 | 0.012132 | P37268,Q96AY3,P42892,Q9NR77,Q96L73,P06753,P02545,Q9Y619,O95155,Q9Y5Y0,Q8WVQ1,Q99567,Q15392,P35637,P23786,Q99720,P57740,O75844,Q96L58 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 0,2,11,273,669,399,534,165,428,188,333,461,203,76,78,105,617,122,515 | 1059,2447,2609,2231,2270,1092,661,1061,1292,122,1425,428,534,399,1428,2483,2558,3227,78,3280,1933,3094,1242,76,0,1574,11,3012,3183,918,1172,2204,617,2693,2177,2855,2729,2322,1205,1582,203,2432,1866,2814,3466,764,795,1365,333,1131,889,1336,2055,2,515,669,1557,461,105,2502,2364,735,2190,2975,273,1399,1842,1492,1630,1680,188,165,1965 | 0.31394007341810976,-0.4721097617635663,-0.5814561396181898,-0.36330308096834,-0.38140051285772825,0.2963686288929385,0.6972889626491571,0.31394007341810976,0.17300089051442,1.978355565936782,0.08448186784031635,1.0065327601008498,0.8352060194424157,1.057703597794576,0.08448186784031635,-0.49029638115367696,-0.5449466965406411,-1.2118458207692089,2.3541899251088996,-1.3061790135246543,-0.20108142022241898,-1.005824441947442,0.20831486901201274,2.37041584169695,5.186433041862088,-0.004375775863415211,3.9028885923934347,-0.9128477418208648,-1.1179452960132723,0.43657813874424445,0.24357584178456979,-0.34522033918629164,0.7490982712358505,-0.6363352046117817,-0.3271522384422823,-0.7649300864530652,-0.6546590794968076,-0.39951268421354885,0.22595196061218203,-0.004375775863415211,1.6139472546177651,-0.4539381330689716,-0.16519022238487766,-0.7281102878395844,-3.7055068029537113,0.5933404260508179,0.5585921060824289,0.13763357601742993,1.2105997259678525,0.27878413552863,0.4715023827975977,0.1553239210492891,-0.25502527446770934,4.993329286903139,0.8695655387205098,0.6972889626491571,0.013423100007657314,0.9552577561979099,2.093282645393226,-0.49029638115367696,-0.4176396446871264,0.6280391487957254,-0.3271522384422823,-0.8757716419980323,1.3457452705931343,0.11992981356626614,-0.1472658952589451,0.0489797444034831,-0.02218841243594591,-0.057855143918590056,1.6972035615388537,1.780200641127462,-0.20108142022241898 | 3,477 |
Monooxygenase activity | 6 | 10 | 2.504672 | 0.012256 | Q16850,P30519,Q6UW02,P61457,Q9Y2Z9,P09601 | Functions | GO Molecular function | msigdb_gomf | 350,5,296,401,30,212 | 3141,212,5,401,674,1274,350,296,425,30 | -1.061809293070439,1.580571395190101,4.573593931116834,1.057703597794576,0.6799948733270359,0.19066452603648326,1.1767019777664645,1.278261105136215,1.0236012369190428,3.2017502522530474 | 3,477 |
Macromolecule deacylation | 13 | 42 | 2.503637 | 0.012292 | Q8IXJ6,Q8N163,Q9ULX6,O95983,Q9UMR5,Q9NTG7,O75608,Q9NUJ1,Q96PK6,O43823,Q96EB6,Q92830,P50897 | Processes and pathways | GO Biological process | msigdb_gobp | 6,139,140,454,113,48,519,52,579,85,547,220,251 | 960,85,519,2714,454,1815,2558,569,858,2170,789,251,3080,1551,2993,2695,2003,3287,2147,1756,664,3122,1866,3418,1247,6,139,1436,1106,2576,220,547,579,1723,2190,48,52,871,1808,1701,140,113 | 0.4016029509522354,2.2240426346319078,0.8523917149803377,-0.6546590794968076,0.9552577561979099,-0.1472658952589451,-0.5449466965406411,0.8007988770829282,0.4889454962781681,-0.3271522384422823,0.5585921060824289,1.4130541216407417,-0.9871961254841282,0.013423100007657314,-0.8943015669385899,-0.6363352046117817,-0.23702965284823038,-1.3061790135246543,-0.30909872995436094,-0.11145955440898236,0.6972889626491571,-1.0244693677889274,-0.16519022238487766,-1.842847311166223,0.20831486901201274,4.573593931116834,1.8629417911591617,0.08448186784031635,0.2963686288929385,-0.5449466965406411,1.547153301208781,0.8352060194424157,0.8007988770829282,-0.09357744939710187,-0.3271522384422823,2.676953256540877,2.628771365546536,0.4889454962781681,-0.1293556878583202,-0.07570932756690205,1.8629417911591617,2.0276691307788863 | 3,477 |
Response to oxidative stress | 17 | 98 | 2.502864 | 0.012319 | P09874,P00374,P30519,Q8IXJ6,Q9NR28,Q99720,Q15392,P31749,P05067,P46108,O95831,O43169,Q7Z2K6,P33527,Q15165,Q96IZ0,P09601 | Processes and pathways | GO Biological process | msigdb_gobp | 98,37,5,6,71,105,203,183,124,242,24,53,157,123,120,221,212 | 2738,1880,53,807,1997,3254,689,2508,1140,2612,983,1502,24,37,2164,1931,2420,2924,1815,2310,124,1426,2643,1999,212,98,2761,2481,3376,901,2903,2483,1895,2236,569,1896,2037,3428,1119,1933,3228,3429,2078,3413,5,183,2347,3094,123,2108,1144,2487,3401,2039,2488,242,1637,1689,2202,587,3449,3015,2207,1610,1099,2650,1790,885,479,634,384,120,603,203,266,1648,157,6,952,2973,2576,1801,547,2654,221,1831,1723,3266,105,433,2062,71,995,2157,2583,977,551,452 | -0.6729984707451497,-0.18312871527243837,2.6126927177320334,0.541199255452286,-0.23702965284823038,-1.2495267166562185,0.6626885650713121,-0.5084980423896142,0.26118655325487,-0.5814561396181898,0.3840961570394507,0.031208258927758886,3.264732786733322,3.0119990384229687,-0.3271522384422823,-0.20108142022241898,-0.4539381330689716,-0.8387603079978073,-0.1472658952589451,-0.39951268421354885,1.9618978796135385,0.08448186784031635,-0.5997337881958207,-0.23702965284823038,1.580571395190101,2.1260307366165443,-0.6913534327057209,-0.49029638115367696,-1.61105182439162,0.4540466096167885,-0.8202787828880227,-0.49029638115367696,-0.18312871527243837,-0.36330308096834,0.8007988770829282,-0.18312871527243837,-0.25502527446770934,-1.9012348366427068,0.27878413552863,-0.20108142022241898,-1.2118458207692089,-1.9012348366427068,-0.2730352960413805,-1.8234243897747608,4.573593931116834,1.6972035615388537,-0.4176396446871264,-1.005824441947442,1.978355565936782,-0.29105976522553345,0.26118655325487,-0.49029638115367696,-1.7459284461455995,-0.25502527446770934,-0.49029638115367696,1.446643388062751,-0.04001485370627771,-0.07570932756690205,-0.34522033918629164,0.7835773618879034,-2.176126586591169,-0.9128477418208648,-0.34522033918629164,-0.02218841243594591,0.2963686288929385,-0.5997337881958207,-0.1293556878583202,0.4715023827975977,0.9210161159169525,0.7318406263618454,1.0917600484003518,1.9948033201355835,0.7663438381457375,1.6139472546177651,1.362588845676582,-0.04001485370627771,1.796769241269738,4.573593931116834,0.4190969319876285,-0.8757716419980323,-0.5449466965406411,-0.1293556878583202,0.8352060194424157,-0.5997337881958207,1.547153301208781,-0.1472658952589451,-0.09357744939710187,-1.2495267166562185,2.093282645393226,1.0065327601008498,-0.25502527446770934,2.419037471494315,0.3840961570394507,-0.30909872995436094,-0.5449466965406411,0.4016029509522354,0.8352060194424157,0.972361052266646 | 3,477 |
Protease | 28 | 120 | 2.499042 | 0.012453 | P67812,O43847,P42892,Q5JRX3,Q9BYT8,Q86UT6,Q7Z2K6,Q92905,P34913,Q10713,P55786,O95630,Q9HB40,P22695,Q8TCT9,Q9Y4P1,Q01804,Q9UIQ6,Q8NHP8,Q96AE4,P42785,Q92945,Q9H3G5,Q96RU2,Q96I24,P61978,O75844,Q9NZ08 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 130,505,11,390,408,543,157,546,29,286,32,411,173,298,441,337,329,81,84,215,93,225,96,108,245,252,122,126 | 2416,1780,2712,3076,1924,505,2232,1260,122,2823,411,1686,2901,2449,1743,1893,3031,3115,1353,2903,2034,3270,298,2168,3093,2723,2107,29,2487,2488,616,93,11,2172,963,2280,2591,790,1548,760,2317,3119,3231,1299,32,1788,3402,252,130,329,1066,2319,1579,286,2796,1175,3385,2774,1328,2111,1207,3058,3040,2519,540,390,2325,1613,2700,2399,2290,1981,157,1279,543,1984,1436,846,84,1438,1364,652,441,1762,3062,2359,2294,546,1154,225,1311,215,2523,245,910,2120,108,1724,3266,1948,718,1835,1727,408,96,1055,173,2736,3342,126,1840,833,81,2757,2879,875,337,1235,1922,2025 | -0.4539381330689716,-0.1293556878583202,-0.6546590794968076,-0.9871961254841282,-0.20108142022241898,0.8695655387205098,-0.36330308096834,0.19066452603648326,1.978355565936782,-0.746512291400033,1.0406581721072192,-0.07570932756690205,-0.8202787828880227,-0.4721097617635663,-0.11145955440898236,-0.18312871527243837,-0.9314102255969627,-1.0244693677889274,0.13763357601742993,-0.8202787828880227,-0.25502527446770934,-1.2683932884585893,1.2613624491146502,-0.3271522384422823,-1.005824441947442,-0.6546590794968076,-0.29105976522553345,3.217508323661947,-0.49029638115367696,-0.49029638115367696,0.7490982712358505,2.1750800789820577,3.9028885923934347,-0.3271522384422823,0.4016029509522354,-0.38140051285772825,-0.5631937933047674,0.5585921060824289,0.013423100007657314,0.5933404260508179,-0.39951268421354885,-1.0244693677889274,-1.2118458207692089,0.17300089051442,3.1702091254103086,-0.1293556878583202,-1.7459284461455995,1.4130541216407417,1.8959673156390773,1.2105997259678525,0.31394007341810976,-0.39951268421354885,-0.004375775863415211,1.295148685478845,-0.7097240200629163,0.24357584178456979,-1.6302629358411647,-0.6913534327057209,0.1553239210492891,-0.29105976522553345,0.22595196061218203,-0.9499890775959331,-0.9314102255969627,-0.5084980423896142,0.8352060194424157,1.0747375459534367,-0.39951268421354885,-0.02218841243594591,-0.6363352046117817,-0.43578144422450665,-0.38140051285772825,-0.2190483838022552,1.796769241269738,0.19066452603648326,0.8352060194424157,-0.2190483838022552,0.08448186784031635,0.5063759878506557,2.2403443097030906,0.08448186784031635,0.13763357601742993,0.7145708685502362,0.9894527093654699,-0.11145955440898236,-0.9499890775959331,-0.4176396446871264,-0.38140051285772825,0.8352060194424157,0.26118655325487,1.530428347164649,0.17300089051442,1.580571395190101,-0.5084980423896142,1.446643388062751,0.4540466096167885,-0.29105976522553345,2.0768939693689594,-0.09357744939710187,-1.2495267166562185,-0.20108142022241898,0.645370002187069,-0.1472658952589451,-0.09357744939710187,1.057703597794576,2.1587399725073695,0.3314985089593542,1.747032703853092,-0.6546590794968076,-1.4389883090290831,1.9289526113250501,-0.1472658952589451,0.5237938951093771,2.289192128383176,-0.6729984707451497,-0.7833637290550592,0.4889454962781681,1.2105997259678525,0.22595196061218203,-0.18312871527243837,-0.23702965284823038 | 3,477 |
Inorganic anion transport | 8 | 30 | 2.496698 | 0.012536 | P21796,P08183,Q9C0H2,P30536,Q9UHG3,P45880,O43681,P33527 | Processes and pathways | GO Biological process | msigdb_gobp | 128,33,335,43,13,79,176,123 | 3324,1197,176,1706,33,2884,128,43,123,79,759,3365,1509,1787,2041,1009,331,1068,636,1794,2630,1076,1484,335,954,672,13,474,2193,3415 | -1.419961736541305,0.22595196061218203,1.7138236090436918,-0.09357744939710187,3.1544260335844876,-0.8018132756130776,1.9124649794523898,2.7890650119210334,1.978355565936782,2.3379546179921205,0.5933404260508179,-1.5726858889559527,0.031208258927758886,-0.1293556878583202,-0.25502527446770934,0.3665765114452106,1.2105997259678525,0.31394007341810976,0.7318406263618454,-0.1293556878583202,-0.5814561396181898,0.31394007341810976,0.0489797444034831,1.2105997259678525,0.4190969319876285,0.6972889626491571,3.76393416406384,0.938142788391448,-0.3271522384422823,-1.8234243897747608 | 3,477 |
Generalized amyotrophy | 9 | 26 | 2.494049 | 0.01263 | Q8IY17,Q99567,P35637,Q9Y2U8,Q03252,Q13501,Q13148,P06753,P22626 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 99,461,76,475,490,403,402,399,155 | 2609,1810,1094,534,399,812,155,76,1898,2727,2204,2794,490,1512,402,403,2433,99,1285,461,1958,1316,475,2133,2307,1601 | -0.5814561396181898,-0.1472658952589451,0.2963686288929385,0.8352060194424157,1.057703597794576,0.541199255452286,1.796769241269738,2.37041584169695,-0.18312871527243837,-0.6546590794968076,-0.34522033918629164,-0.7097240200629163,0.9038777056804731,0.031208258927758886,1.057703597794576,1.057703597794576,-0.4539381330689716,2.1260307366165443,0.19066452603648326,0.9552577561979099,-0.20108142022241898,0.17300089051442,0.938142788391448,-0.29105976522553345,-0.38140051285772825,-0.004375775863415211 | 3,477 |
Peroxisomes | 8 | 16 | 2.475195 | 0.013316 | O00116,O75521,O75381,Q15067,P56589,Q5T8D3,P40855,Q9BY49 | Localization | Protein Atlas Subcellular | protein_atlas_subcellular_location_all | 421,167,197,172,239,364,246,285 | 421,476,1349,197,167,3257,1745,2314,246,2281,239,172,364,2150,285,704 | 1.0236012369190428,0.9210161159169525,0.13763357601742993,1.630619414996261,1.7636218040365772,-1.2495267166562185,-0.11145955440898236,-0.39951268421354885,1.4298541607079167,-0.38140051285772825,1.463421832352514,1.747032703853092,1.1427591973209943,-0.30909872995436094,1.3120252200291715,0.6626885650713121 | 3,477 |
Protein processing | 16 | 47 | 2.473553 | 0.013378 | P67812,P09874,Q9NQH7,Q9HB09,P42892,Q5JRX3,Q15392,O75503,P42575,O75787,Q8TCT9,O75844,O75976,Q9H9S5,Q92896,Q10713 | Processes and pathways | GO Biological process | msigdb_gobp | 130,98,720,426,11,390,203,325,616,613,441,122,317,450,418,286 | 2553,1883,807,1260,325,613,122,317,1165,2509,3427,2201,98,3178,2903,1241,1544,2488,616,11,2742,1299,1788,130,1609,286,2282,1272,203,390,2325,2894,441,1800,418,2361,1945,2654,1724,1948,718,450,426,720,1531,1491,1235 | -0.5449466965406411,-0.18312871527243837,0.541199255452286,0.19066452603648326,1.2105997259678525,0.7490982712358505,1.978355565936782,1.2275317897751026,0.24357584178456979,-0.5084980423896142,-1.9012348366427068,-0.34522033918629164,2.1260307366165443,-1.1179452960132723,-0.8202787828880227,0.20831486901201274,0.013423100007657314,-0.49029638115367696,0.7490982712358505,3.9028885923934347,-0.6729984707451497,0.17300089051442,-0.1293556878583202,1.8959673156390773,-0.02218841243594591,1.295148685478845,-0.38140051285772825,0.19066452603648326,1.6139472546177651,1.0747375459534367,-0.39951268421354885,-0.8018132756130776,0.9894527093654699,-0.1293556878583202,1.0406581721072192,-0.4176396446871264,-0.20108142022241898,-0.5997337881958207,-0.09357744939710187,-0.20108142022241898,0.645370002187069,0.972361052266646,1.0236012369190428,0.645370002187069,0.031208258927758886,0.0489797444034831,0.22595196061218203 | 3,477 |
Sumoylation of dna damage response and repair proteins | 17 | 47 | 2.447268 | 0.014394 | Q9BTX1,P09874,P49790,Q99567,Q9BVL2,Q96SB8,P38398,P35658,P52948,P57740,O15504,Q96MG7,Q8NFH4,P41208,Q14191,P37198,Q8N1F7 | Processes and pathways | Reactome Pathways | msigdb_reactome | 484,98,815,461,594,496,647,646,760,617,584,670,439,374,634,189,352 | 584,1703,1885,1814,98,939,2104,646,189,647,374,1712,815,816,760,617,2910,2952,1100,1434,634,2284,2322,986,2324,1013,1151,1760,352,1519,2521,439,1672,1365,1073,1412,2018,670,496,1219,461,484,594,1729,1440,1599,1878 | 0.7835773618879034,-0.09357744939710187,-0.18312871527243837,-0.1472658952589451,2.1260307366165443,0.4190969319876285,-0.29105976522553345,0.7145708685502362,1.6805731451820296,0.7145708685502362,1.125770842652169,-0.09357744939710187,0.541199255452286,0.541199255452286,0.5933404260508179,0.7490982712358505,-0.8202787828880227,-0.8572579084205912,0.2963686288929385,0.08448186784031635,0.7318406263618454,-0.38140051285772825,-0.39951268421354885,0.3840961570394507,-0.39951268421354885,0.3665765114452106,0.26118655325487,-0.11145955440898236,1.1767019777664645,0.031208258927758886,-0.5084980423896142,0.9894527093654699,-0.057855143918590056,0.13763357601742993,0.31394007341810976,0.10221259161251053,-0.23702965284823038,0.6972889626491571,0.9038777056804731,0.22595196061218203,0.9552577561979099,0.9210161159169525,0.7835773618879034,-0.09357744939710187,0.08448186784031635,-0.004375775863415211,-0.16519022238487766 | 3,477 |
Fat cell differentiation | 8 | 27 | 2.440923 | 0.01465 | P31751,Q8IXJ6,Q9BRK5,Q02252,Q96A49,P31749,Q9NZ08,Q8N4Q0 | Processes and pathways | GO Biological process | msigdb_gobp | 192,6,169,49,314,183,126,191 | 2924,183,192,1323,3157,49,1512,2695,2542,2252,2255,1866,731,6,191,3186,314,3046,547,1216,2654,394,169,2154,850,1368,126 | -0.8387603079978073,1.6972035615388537,1.6472810988328224,0.1553239210492891,-1.0805044162419772,2.6609016141419497,0.031208258927758886,-0.6363352046117817,-0.5267147969292446,-0.36330308096834,-0.36330308096834,-0.16519022238487766,0.6280391487957254,4.573593931116834,1.663932333233678,-1.1179452960132723,1.2444526873850936,-0.9314102255969627,0.8352060194424157,0.22595196061218203,-0.5997337881958207,1.0747375459534367,1.7636218040365772,-0.30909872995436094,0.5063759878506557,0.13763357601742993,1.9289526113250501 | 3,477 |
Phosphatidylinositol 3 kinase signaling | 8 | 17 | 2.420301 | 0.015508 | O95630,Q8IXJ6,O00165,P22681,Q07021,P31749,P46934,Q10713 | Processes and pathways | GO Biological process | msigdb_gobp | 411,6,166,429,301,183,62,286 | 166,1059,2376,411,2721,429,183,62,2207,1903,301,286,6,797,3406,547,1598 | 1.7636218040365772,0.31394007341810976,-0.43578144422450665,1.0406581721072192,-0.6546590794968076,1.0065327601008498,1.6972035615388537,2.4998877799465182,-0.34522033918629164,-0.18312871527243837,1.2613624491146502,1.295148685478845,4.573593931116834,0.5585921060824289,-1.765273233178852,0.8352060194424157,-0.004375775863415211 | 3,477 |
Inositol lipid mediated signaling | 9 | 22 | 2.414769 | 0.015745 | O95630,Q8IXJ6,O00165,P42356,P22681,Q07021,P46934,P31749,Q10713 | Processes and pathways | GO Biological process | msigdb_gobp | 411,6,166,522,429,301,62,183,286 | 166,1059,2376,2553,411,1894,2721,429,183,522,62,2207,1903,301,286,6,797,3406,547,799,1598,2737 | 1.7636218040365772,0.31394007341810976,-0.43578144422450665,-0.5449466965406411,1.0406581721072192,-0.18312871527243837,-0.6546590794968076,1.0065327601008498,1.6972035615388537,0.8523917149803377,2.4998877799465182,-0.34522033918629164,-0.18312871527243837,1.2613624491146502,1.295148685478845,4.573593931116834,0.5585921060824289,-1.765273233178852,0.8352060194424157,0.5585921060824289,-0.004375775863415211,-0.6546590794968076 | 3,477 |
mRNA transport | 28 | 67 | 2.414229 | 0.015769 | Q07955,Q8TD16,P82979,P35658,O60318,Q96FV9,P22626,P49790,Q16629,P49792,Q96PU8,P09651,Q96ST2,Q8NFH4,Q53F19,P37198,Q06787,Q99567,Q9BVL2,Q6I9Y2,O15504,Q9BZI7,Q9BTX1,Q8N1F7,Q92945,P57740,P41208,P52948 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 258,778,633,646,642,926,155,815,923,816,304,812,700,439,311,189,824,461,594,199,584,735,484,352,225,617,374,760 | 2586,1780,2417,584,642,1060,1885,812,939,155,646,189,2424,374,2725,815,816,1607,760,617,2771,3196,633,1098,824,258,1642,1643,1100,1148,2773,923,311,2324,199,1278,1013,2009,352,2521,439,2935,778,1672,1365,2402,1412,225,2018,926,2220,304,700,461,484,594,1729,1953,735,1440,1840,1489,1599,2228,3027,2337,2025 | -0.5631937933047674,-0.1293556878583202,-0.4539381330689716,0.7835773618879034,0.7145708685502362,0.31394007341810976,-0.18312871527243837,0.541199255452286,0.4190969319876285,1.796769241269738,0.7145708685502362,1.6805731451820296,-0.4539381330689716,1.125770842652169,-0.6546590794968076,0.541199255452286,0.541199255452286,-0.02218841243594591,0.5933404260508179,0.7490982712358505,-0.6913534327057209,-1.1366911787908272,0.7318406263618454,0.2963686288929385,0.5237938951093771,1.3962432420799271,-0.04001485370627771,-0.04001485370627771,0.2963686288929385,0.26118655325487,-0.6913534327057209,0.43657813874424445,1.2444526873850936,-0.39951268421354885,1.630619414996261,0.19066452603648326,0.3665765114452106,-0.23702965284823038,1.1767019777664645,-0.5084980423896142,0.9894527093654699,-0.8387603079978073,0.5759724840094101,-0.057855143918590056,0.13763357601742993,-0.43578144422450665,0.10221259161251053,1.530428347164649,-0.23702965284823038,0.43657813874424445,-0.34522033918629164,1.2613624491146502,0.6626885650713121,0.9552577561979099,0.9210161159169525,0.7835773618879034,-0.09357744939710187,-0.20108142022241898,0.6280391487957254,0.08448186784031635,-0.1472658952589451,0.0489797444034831,-0.004375775863415211,-0.34522033918629164,-0.9128477418208648,-0.39951268421354885,-0.23702965284823038 | 3,477 |
Rna splicing | 79 | 246 | 2.413222 | 0.015812 | O75940,Q86V81,P98179,Q14011,O75400,Q92841,P38159,Q96PK6,P31942,Q96I25,P23246,P35637,P52272,P55081,Q92804,Q15233,P52597,O75312,P55795,P62312,Q15427,P31943,P51116,Q8N163,Q9ULX6,P19338,Q8IY67,O60828,P22626,Q9Y2W2,Q5T200,Q15459,O95391,P62310,P62995,Q96ST2,P49761,O75475,Q16637,Q6I9Y2,Q96E39,P78332,O75525,Q01130,Q92945,Q86UA1,P51114,Q15637,P52756,Q13242,Q9BWF3,P51991,O95400,Q07666,P61978,O60506,Q07955,Q9UHX1,O43390,Q13123,Q9UBB9,P98175,Q13595,Q14320,Q96PU8,Q07021,O60508,O75494,Q9P013,Q8WXF0,P38432,Q15007,Q9Y2W1,Q13148,Q8IXT5,Q8IWZ8,P67809,Q96EP5,O00566 | Processes and pathways | GO Biological process | msigdb_gobp | 3,544,34,35,532,561,55,579,59,578,569,76,587,80,89,603,94,599,106,618,620,115,631,139,140,644,667,661,155,687,678,675,175,178,179,700,184,689,194,199,206,209,211,213,225,729,223,726,227,233,749,237,236,253,252,256,258,260,264,272,274,275,287,288,304,301,323,324,345,359,361,383,398,402,417,437,444,494,486 | 3052,1090,486,2898,1468,1139,1469,877,264,1682,3325,2308,1022,2270,2661,2760,256,323,661,599,532,689,324,211,1261,2380,810,3,2840,1472,3009,175,236,3268,1166,900,2033,2139,1968,1427,812,1263,2844,1688,1660,1200,1096,2074,2141,644,155,569,2722,1572,2000,3228,2239,59,115,76,55,361,2424,2619,1322,1821,1121,184,223,631,237,587,1607,94,227,760,1509,80,3034,106,2535,252,3305,2692,178,618,3387,3451,3417,179,444,209,2495,2593,1098,275,34,3157,213,2042,3396,824,301,253,258,2179,1642,1643,1858,859,2043,840,272,402,233,1050,1174,2392,1245,2854,920,287,1148,2773,2517,35,288,2743,1692,907,1454,1386,383,826,2286,603,3149,620,2046,675,726,923,194,1360,1693,2519,1516,678,3172,1906,1719,199,924,3060,1278,2545,1456,969,729,544,2009,3160,437,1585,417,667,3299,139,2935,2818,1185,888,3087,1619,359,3061,1153,89,561,889,225,1985,2735,746,2957,206,494,926,578,2220,927,579,304,830,1947,700,1015,1725,831,2122,2501,2470,2803,749,2781,3250,2833,2820,1595,1772,1730,2752,2302,2919,1314,2410,1958,2020,2475,996,345,274,1287,260,1490,3139,1562,1288,1087,140,2476,1420,3075,2638,398,687,1633,3447,2414,835,2605,2859,3253,1058,3309,2337 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| 3,477 |
Abnormal neuron morphology | 9 | 28 | 2.406341 | 0.016113 | Q16637,Q8IY17,Q99720,P35637,Q13501,Q13148,Q15165,Q92804,P22626 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 194,99,105,76,403,402,120,89,155 | 2609,1425,2664,3400,812,1745,3227,155,76,465,1354,2204,2794,402,403,1175,1580,120,194,99,847,89,991,105,2405,913,1958,1809 | -0.5814561396181898,0.08448186784031635,-0.6180267920736977,-1.7459284461455995,0.541199255452286,-0.11145955440898236,-1.2118458207692089,1.796769241269738,2.37041584169695,0.938142788391448,0.13763357601742993,-0.34522033918629164,-0.7097240200629163,1.057703597794576,1.057703597794576,0.24357584178456979,-0.004375775863415211,1.9948033201355835,1.6472810988328224,2.1260307366165443,0.5063759878506557,2.2240426346319078,0.3840961570394507,2.093282645393226,-0.43578144422450665,0.4540466096167885,-0.20108142022241898,-0.1293556878583202 | 3,477 |
Morphological abnormality of the corticospinal tract | 6 | 18 | 2.390634 | 0.016819 | O00400,P00846,P35637,Q13501,Q13148,Q12768 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 293,10,76,403,402,538 | 293,2196,2378,10,1503,1380,76,2794,1510,538,2352,402,403,1580,571,887,2064,2067 | 1.278261105136215,-0.34522033918629164,-0.43578144422450665,3.9336836738560215,0.031208258927758886,0.11992981356626614,2.37041584169695,-0.7097240200629163,0.031208258927758886,0.8352060194424157,-0.4176396446871264,1.057703597794576,1.057703597794576,-0.004375775863415211,0.8007988770829282,0.4715023827975977,-0.25502527446770934,-0.25502527446770934 | 3,477 |
Lipid localization | 24 | 81 | 2.38745 | 0.016966 | Q9BZF3,Q8WTV0,Q9H6V9,Q96EB6,P08183,Q9BQE5,P35610,P30536,O15118,Q9H4L5,P31749,P31751,Q14108,Q16739,P23786,Q9UHB6,Q9Y3D6,P35790,O43772,Q99720,Q9H2V7,P14174,P33527,Q7Z3C6 | Processes and pathways | GO Biological process | msigdb_gobp | 7,19,281,547,33,164,536,43,553,180,183,192,330,198,78,473,346,92,97,105,369,373,123,512 | 1403,3473,553,567,1197,97,1349,1423,1450,2418,1851,1887,1889,1931,2420,2201,1141,2902,2716,33,709,373,3179,2237,1745,78,2314,858,43,183,192,1746,123,536,92,3457,1122,3185,2649,3444,1610,3073,330,674,3377,198,1068,636,2289,2005,512,1030,2089,2748,19,1032,1285,547,1077,105,164,2406,3161,2154,850,7,1368,369,180,2999,281,2552,1466,2334,473,2529,1491,2602,346,723,2656 | 0.10221259161251053,-6.7471838245148525,0.8180084181768476,0.8007988770829282,0.22595196061218203,2.1423901995972563,0.13763357601742993,0.08448186784031635,0.06673759969946712,-0.4539381330689716,-0.16519022238487766,-0.18312871527243837,-0.18312871527243837,-0.20108142022241898,-0.4539381330689716,-0.34522033918629164,0.26118655325487,-0.8202787828880227,-0.6546590794968076,3.1544260335844876,0.645370002187069,1.125770842652169,-1.1179452960132723,-0.36330308096834,-0.11145955440898236,2.3541899251088996,-0.39951268421354885,0.4889454962781681,2.7890650119210334,1.6972035615388537,1.6472810988328224,-0.11145955440898236,1.978355565936782,0.8352060194424157,2.1750800789820577,-2.275298022897621,0.27878413552863,-1.1179452960132723,-0.5997337881958207,-2.0971723037928203,-0.02218841243594591,-0.9685843575272131,1.2105997259678525,0.6799948733270359,-1.61105182439162,1.630619414996261,0.31394007341810976,0.7318406263618454,-0.38140051285772825,-0.23702965284823038,0.8695655387205098,0.34904397515841284,-0.2730352960413805,-0.6729984707451497,3.4997508506844,0.34904397515841284,0.19066452603648326,0.8352060194424157,0.31394007341810976,2.093282645393226,1.780200641127462,-0.43578144422450665,-1.0805044162419772,-0.30909872995436094,0.5063759878506557,4.573593931116834,0.13763357601742993,1.1427591973209943,1.7138236090436918,-0.8943015669385899,1.328890738532374,-0.5267147969292446,0.06673759969946712,-0.39951268421354885,0.938142788391448,-0.5084980423896142,0.0489797444034831,-0.5631937933047674,1.1936564655011561,0.645370002187069,-0.5997337881958207 | 3,477 |
Epigenetic regulator | 16 | 34 | 2.38743 | 0.016967 | P45973,Q16637,Q86X55,Q6PL18,Q13185,Q8IXJ6,O96028,Q9H7B4,Q14781,O60885,Q9NPI1,Q12888,Q9NTG7,Q96L73,Q96EB6,Q8WTS6 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 602,194,731,480,984,6,222,268,986,981,370,964,48,669,547,545 | 2898,2760,1926,981,222,1379,2384,602,1786,1172,1244,964,984,2003,986,194,480,987,1129,731,6,1072,545,1186,2576,547,1337,669,1834,2122,268,2301,370,48 | -0.8202787828880227,-0.6913534327057209,-0.20108142022241898,0.3840961570394507,1.530428347164649,0.11992981356626614,-0.43578144422450665,0.7663438381457375,-0.1293556878583202,0.24357584178456979,0.20831486901201274,0.4016029509522354,0.3840961570394507,-0.23702965284823038,0.3840961570394507,1.6472810988328224,0.9210161159169525,0.3840961570394507,0.27878413552863,0.6280391487957254,4.573593931116834,0.31394007341810976,0.8352060194424157,0.24357584178456979,-0.5449466965406411,0.8352060194424157,0.1553239210492891,0.6972889626491571,-0.1472658952589451,-0.29105976522553345,1.362588845676582,-0.38140051285772825,1.1427591973209943,2.676953256540877 | 3,477 |
Cholesterol binding | 7 | 15 | 2.38315 | 0.017165 | P21796,Q9BZF3,Q14108,P35610,P30536,P45880,Q9H4L5 | Functions | GO Molecular function | msigdb_gomf | 128,7,330,536,43,79,180 | 553,1500,1425,2235,128,1745,43,536,79,3185,330,3377,850,7,180 | 0.8180084181768476,0.031208258927758886,0.08448186784031635,-0.36330308096834,1.9124649794523898,-0.11145955440898236,2.7890650119210334,0.8352060194424157,2.3379546179921205,-1.1179452960132723,1.2105997259678525,-1.61105182439162,0.5063759878506557,4.573593931116834,1.7138236090436918 | 3,477 |
Spliceosomal complex | 24 | 134 | 2.38117 | 0.017258 | O60506,Q07955,O75940,O43390,Q13123,Q9UBB9,P22626,Q13595,P98179,Q14011,O95391,P62310,P62995,P38159,P31942,O60508,Q96E39,P55081,Q01130,P52597,P52756,P51991,P31943,P61978 | Localization | GO Cellular component | msigdb_gocc | 256,258,3,264,272,274,155,287,34,35,175,178,179,55,59,323,206,80,213,94,227,237,115,252 | 1139,1469,877,264,1682,3325,2308,1022,2270,2661,256,323,532,1261,2380,810,3,2840,3009,175,3268,900,2033,2139,1968,1427,812,1263,2844,1688,1200,1096,2074,644,155,1572,59,115,55,2424,2619,1322,237,587,94,227,1509,80,1381,3034,252,2692,178,618,3387,3451,3417,179,444,2593,34,3157,213,2042,258,840,272,1245,2854,920,287,2773,35,2743,907,2286,2183,3149,620,2046,675,726,1360,2519,3172,1906,924,3060,1456,729,544,437,3299,888,3087,1620,1153,2295,889,1985,746,2957,206,578,1725,2470,2803,2781,1771,2820,1595,2302,2919,1314,1958,2020,345,551,274,1490,3139,1562,1288,2476,1420,3075,687,1633,3447,2414,835,2605,3309,2337 | 0.26118655325487,0.0489797444034831,0.4715023827975977,1.362588845676582,-0.07570932756690205,-1.419961736541305,-0.39951268421354885,0.34904397515841284,-0.38140051285772825,-0.6180267920736977,1.3962432420799271,1.2105997259678525,0.8352060194424157,0.19066452603648326,-0.43578144422450665,0.541199255452286,4.648937862838768,-0.7649300864530652,-0.9128477418208648,1.730433314315435,-1.2683932884585893,0.4540466096167885,-0.25502527446770934,-0.30909872995436094,-0.2190483838022552,0.08448186784031635,0.541199255452286,0.19066452603648326,-0.7649300864530652,-0.07570932756690205,0.22595196061218203,0.2963686288929385,-0.2730352960413805,0.7145708685502362,1.796769241269738,-0.004375775863415211,2.5805082703873468,2.0112411668915997,2.6126927177320334,-0.4539381330689716,-0.5814561396181898,0.1553239210492891,1.463421832352514,0.7835773618879034,2.1587399725073695,1.5136927513121756,0.031208258927758886,2.321709897885349,0.11992981356626614,-0.9314102255969627,1.4130541216407417,-0.6363352046117817,1.7138236090436918,0.7490982712358505,-1.6494929110757173,-2.215730782294194,-1.842847311166223,1.7138236090436918,0.972361052266646,-0.5631937933047674,3.1070264246639914,-1.0805044162419772,1.580571395190101,-0.25502527446770934,1.3962432420799271,0.5063759878506557,1.3457452705931343,0.20831486901201274,-0.7649300864530652,0.43657813874424445,1.295148685478845,-0.6913534327057209,3.1070264246639914,-0.6729984707451497,0.4540466096167885,-0.38140051285772825,-0.3271522384422823,-1.061809293070439,0.7490982712358505,-0.25502527446770934,0.6799948733270359,0.6280391487957254,0.13763357601742993,-0.5084980423896142,-1.0992163962621977,-0.18312871527243837,0.43657813874424445,-0.9499890775959331,0.06673759969946712,0.6280391487957254,0.8352060194424157,0.9894527093654699,-1.3440352974719634,0.4715023827975977,-0.9871961254841282,-0.02218841243594591,0.26118655325487,-0.38140051285772825,0.4715023827975977,-0.2190483838022552,0.6106959688336498,-0.8572579084205912,1.6139472546177651,0.8007988770829282,-0.09357744939710187,-0.4721097617635663,-0.7097240200629163,-0.6913534327057209,-0.11145955440898236,-0.7281102878395844,-0.004375775863415211,-0.38140051285772825,-0.8202787828880227,0.17300089051442,-0.20108142022241898,-0.23702965284823038,1.1936564655011561,0.8352060194424157,1.3457452705931343,0.0489797444034831,-1.0431309642750133,0.013423100007657314,0.19066452603648326,-0.4721097617635663,0.10221259161251053,-0.9685843575272131,0.6799948733270359,-0.02218841243594591,-2.1366073426776953,-0.43578144422450665,0.5237938951093771,-0.5631937933047674,-1.3629900695977135,-0.39951268421354885 | 3,477 |
Zinc ion binding | 24 | 151 | 2.374105 | 0.017592 | Q8IXJ6,P42892,Q5JRX3,P04150,Q8NCC3,P55786,Q00403,O95391,Q9NTG7,Q9BQG2,Q9Y3Z3,Q9HD42,P00813,Q05682,O75976,Q8N4Q0,Q9UIQ6,O43823,P09874,Q9UPP1,P36551,P09960,Q9NZ08,P05771 | Functions | GO Molecular function | msigdb_gomf | 6,11,390,389,153,32,160,175,48,50,316,187,58,309,317,191,81,85,98,100,356,110,126,127 | 773,1091,1848,85,1927,599,3141,317,1849,2714,2478,2554,1569,2555,175,2418,2614,1930,1814,58,389,758,1815,127,2716,1427,98,2843,110,3055,1353,724,1708,1118,2384,3345,2168,2888,858,1785,2423,3281,356,647,3262,11,465,2172,1636,488,3156,2688,2490,2492,1173,2827,32,2672,2494,160,3421,649,3234,309,1975,2890,840,2180,2208,2993,403,1101,1303,1327,2147,1386,2892,1359,1514,2046,2212,2047,726,923,2519,1555,2113,390,1517,3288,1276,1308,2288,2700,924,2468,1456,1941,730,1247,2291,6,1151,191,625,1072,153,1762,1106,1107,2119,2295,1589,1337,1251,669,1767,1219,2222,1110,50,749,3331,3048,2301,187,48,1442,3412,3342,126,999,1444,2921,2922,2064,81,978,722,874,1114,2877,1115,100,2757,1631,316,1235,1158,2336,1965 | 0.5759724840094101,0.2963686288929385,-0.16519022238487766,2.2240426346319078,-0.20108142022241898,0.7663438381457375,-1.061809293070439,1.2275317897751026,-0.16519022238487766,-0.6546590794968076,-0.49029638115367696,-0.5449466965406411,-0.004375775863415211,-0.5449466965406411,1.730433314315435,-0.4539381330689716,-0.5814561396181898,-0.20108142022241898,-0.1472658952589451,2.596605026352921,1.0747375459534367,0.5933404260508179,-0.1472658952589451,1.9124649794523898,-0.6546590794968076,0.08448186784031635,2.1260307366165443,-0.7649300864530652,2.0276691307788863,-0.9499890775959331,0.13763357601742993,0.6280391487957254,-0.09357744939710187,0.27878413552863,-0.43578144422450665,-1.4580330078033252,-0.3271522384422823,-0.8018132756130776,0.4889454962781681,-0.1293556878583202,-0.4539381330689716,-1.3061790135246543,1.1597362320078495,0.7145708685502362,-1.2495267166562185,3.9028885923934347,0.938142788391448,-0.3271522384422823,-0.04001485370627771,0.9038777056804731,-1.0805044162419772,-0.6363352046117817,-0.49029638115367696,-0.49029638115367696,0.24357584178456979,-0.746512291400033,3.1702091254103086,-0.6180267920736977,-0.49029638115367696,1.780200641127462,-1.8622899706622322,0.7145708685502362,-1.2118458207692089,1.2444526873850936,-0.2190483838022552,-0.8018132756130776,0.5063759878506557,-0.3271522384422823,-0.34522033918629164,-0.8943015669385899,1.057703597794576,0.2963686288929385,0.17300089051442,0.1553239210492891,-0.30909872995436094,0.11992981356626614,-0.8018132756130776,0.13763357601742993,0.031208258927758886,-0.25502527446770934,-0.34522033918629164,-0.25502527446770934,0.6280391487957254,0.43657813874424445,-0.5084980423896142,0.013423100007657314,-0.29105976522553345,1.0747375459534367,0.031208258927758886,-1.3061790135246543,0.19066452603648326,0.17300089051442,-0.38140051285772825,-0.6363352046117817,0.43657813874424445,-0.4721097617635663,0.06673759969946712,-0.20108142022241898,0.6280391487957254,0.20831486901201274,-0.38140051285772825,4.573593931116834,0.26118655325487,1.663932333233678,0.7490982712358505,0.31394007341810976,1.8133276304905637,-0.11145955440898236,0.2963686288929385,0.2963686288929385,-0.29105976522553345,-0.38140051285772825,-0.004375775863415211,0.1553239210492891,0.20831486901201274,0.6972889626491571,-0.11145955440898236,0.22595196061218203,-0.34522033918629164,0.2963686288929385,2.644840990732748,0.6106959688336498,-1.419961736541305,-0.9314102255969627,-0.38140051285772825,1.6972035615388537,2.676953256540877,0.08448186784031635,-1.8040211240822055,-1.4389883090290831,1.9289526113250501,0.3840961570394507,0.08448186784031635,-0.8202787828880227,-0.8202787828880227,-0.25502527446770934,2.289192128383176,0.4016029509522354,0.645370002187069,0.4889454962781681,0.2963686288929385,-0.7833637290550592,0.2963686288929385,2.1260307366165443,-0.6729984707451497,-0.02218841243594591,1.2444526873850936,0.22595196061218203,0.26118655325487,-0.39951268421354885,-0.20108142022241898 | 3,477 |
Positive regulation of mrna splicing via spliceosome | 9 | 17 | 2.370142 | 0.017781 | P98179,Q14011,Q9Y2W1,Q96EP5,Q96E39,P62995,Q15427,P38159,Q13595 | Processes and pathways | GO Biological process | msigdb_gobp | 34,35,398,494,206,179,620,55,287 | 2139,2844,644,3228,55,760,179,34,1643,920,287,35,620,206,494,2476,398 | -0.30909872995436094,-0.7649300864530652,0.7145708685502362,-1.2118458207692089,2.6126927177320334,0.5933404260508179,1.7138236090436918,3.1070264246639914,-0.04001485370627771,0.43657813874424445,1.295148685478845,3.1070264246639914,0.7490982712358505,1.6139472546177651,0.9038777056804731,-0.4721097617635663,1.0747375459534367 | 3,477 |
transporter | 20 | 58 | 2.360966 | 0.018227 | Q99595,O60830,Q9NR77,Q567V2,Q15070,Q9Y619,P41440,Q99808,O43681,Q8NFH4,P37198,Q99567,Q99805,O43615,Q8N1F7,O43772,Q9H2V7,P53985,P57740,Q9HD45 | Functions | Panther Protein class | panther_protein_class | 1,4,273,416,539,165,294,40,176,439,189,461,593,598,352,97,369,238,617,640 | 2269,2837,2657,3177,2417,2759,598,176,97,4,1885,2163,646,189,3401,294,3457,815,710,2315,760,2950,238,1509,2515,617,3184,1100,2892,539,416,1794,1013,352,3398,439,1672,2053,1187,829,2018,1653,461,1,593,40,3105,1655,852,369,1918,640,273,2941,2942,1491,1495,165 | -0.38140051285772825,-0.7649300864530652,-0.6180267920736977,-1.1179452960132723,-0.4539381330689716,-0.6913534327057209,0.7663438381457375,1.7138236090436918,2.1423901995972563,4.61882102015611,-0.18312871527243837,-0.3271522384422823,0.7145708685502362,1.6805731451820296,-1.7459284461455995,1.278261105136215,-2.275298022897621,0.541199255452286,0.645370002187069,-0.39951268421354885,0.5933404260508179,-0.8572579084205912,1.463421832352514,0.031208258927758886,-0.5084980423896142,0.7490982712358505,-1.1179452960132723,0.2963686288929385,-0.8018132756130776,0.8352060194424157,1.0406581721072192,-0.1293556878583202,0.3665765114452106,1.1767019777664645,-1.7266029911540117,0.9894527093654699,-0.057855143918590056,-0.25502527446770934,0.24357584178456979,0.5237938951093771,-0.23702965284823038,-0.04001485370627771,0.9552577561979099,5.037989622421626,0.7835773618879034,2.932574742931529,-1.005824441947442,-0.04001485370627771,0.5063759878506557,1.1427591973209943,-0.18312871527243837,0.7318406263618454,1.3457452705931343,-0.8387603079978073,-0.8387603079978073,0.0489797444034831,0.0489797444034831,1.780200641127462 | 3,477 |
Carboxylic acid transport | 8 | 35 | 2.360055 | 0.018272 | Q9UJS0,Q9Y619,P41440,P30825,P53985,Q9BQT8,P33527,Q96NB2 | Processes and pathways | GO Biological process | msigdb_gobp | 322,165,294,75,238,18,123,95 | 2376,1197,1740,809,2612,1451,2420,1687,1141,1707,373,2721,2314,75,123,294,2950,238,1787,1009,3403,2251,636,2005,2630,95,18,852,611,1838,1466,672,322,2193,165 | -0.43578144422450665,0.22595196061218203,-0.11145955440898236,0.541199255452286,-0.5814561396181898,0.06673759969946712,-0.4539381330689716,-0.07570932756690205,0.26118655325487,-0.09357744939710187,1.125770842652169,-0.6546590794968076,-0.39951268421354885,2.37041584169695,1.978355565936782,1.278261105136215,-0.8572579084205912,1.463421832352514,-0.1293556878583202,0.3665765114452106,-1.7459284461455995,-0.36330308096834,0.7318406263618454,-0.23702965284823038,-0.5814561396181898,2.1587399725073695,3.5153541654854648,0.5063759878506557,0.7663438381457375,-0.1472658952589451,0.06673759969946712,0.6972889626491571,1.2275317897751026,-0.3271522384422823,1.780200641127462 | 3,477 |
Microbody membrane | 9 | 26 | 2.351533 | 0.018696 | O15228,O75381,Q15067,P56589,Q5T8D3,Q9NR77,Q9Y3D6,P40855,Q9BY49 | Localization | GO Cellular component | msigdb_gocc | 388,197,172,239,364,273,346,246,285 | 421,388,1349,2070,197,1851,3030,741,1893,2314,1746,3401,246,883,2281,239,172,364,2255,844,1333,2150,1768,285,273,346 | 1.0236012369190428,1.0747375459534367,0.13763357601742993,-0.2730352960413805,1.630619414996261,-0.16519022238487766,-0.9314102255969627,0.6106959688336498,-0.18312871527243837,-0.39951268421354885,-0.11145955440898236,-1.7459284461455995,1.4298541607079167,0.4715023827975977,-0.38140051285772825,1.463421832352514,1.747032703853092,1.1427591973209943,-0.36330308096834,0.5063759878506557,0.1553239210492891,-0.30909872995436094,-0.11145955440898236,1.3120252200291715,1.3457452705931343,1.1936564655011561 | 3,477 |
Vascular process in circulatory system | 8 | 36 | 2.347635 | 0.018893 | P08183,Q99808,P30825,P42892,Q9HB40,Q16625,P53985,P33527 | Processes and pathways | GO Biological process | msigdb_gobp | 33,40,75,11,173,204,238,123 | 1059,2376,1197,1092,1376,1377,1686,2924,1932,33,709,2313,3223,75,123,294,11,1637,1689,2671,238,1787,3469,3444,1857,1713,906,2287,2251,204,2005,3046,40,173,1231,2193 | 0.31394007341810976,-0.43578144422450665,0.22595196061218203,0.2963686288929385,0.11992981356626614,0.11992981356626614,-0.07570932756690205,-0.8387603079978073,-0.20108142022241898,3.1544260335844876,0.645370002187069,-0.39951268421354885,-1.1930313645227653,2.37041584169695,1.978355565936782,1.278261105136215,3.9028885923934347,-0.04001485370627771,-0.07570932756690205,-0.6180267920736977,1.463421832352514,-0.1293556878583202,-4.43874782781883,-2.0971723037928203,-0.16519022238487766,-0.09357744939710187,0.4540466096167885,-0.38140051285772825,-0.36330308096834,1.6139472546177651,-0.23702965284823038,-0.9314102255969627,2.932574742931529,1.747032703853092,0.22595196061218203,-0.3271522384422823 | 3,477 |
Peptidyl proline modification | 8 | 38 | 2.344673 | 0.019044 | Q96AY3,O75718,O95302,Q9Y680,O15460,Q15257,Q9NWM8,P13674 | Processes and pathways | GO Biological process | msigdb_gobp | 2,261,8,141,208,146,119,217 | 1564,208,3325,261,8,1999,217,2792,265,3413,1429,3313,816,1065,1049,1269,3017,885,1667,2392,1691,3217,762,146,525,2114,2893,972,2,1985,2654,3237,2820,119,1420,2159,2605,141 | -0.004375775863415211,1.5972645904672784,-1.419961736541305,1.3794214931092326,4.528304336811979,-0.23702965284823038,1.5638676413060804,-0.7097240200629163,1.362588845676582,-1.8234243897747608,0.08448186784031635,-1.3819626870605868,0.541199255452286,0.31394007341810976,0.3314985089593542,0.19066452603648326,-0.9128477418208648,0.4715023827975977,-0.057855143918590056,-0.43578144422450665,-0.07570932756690205,-1.1742341486986292,0.5933404260508179,1.829875834701021,0.8523917149803377,-0.29105976522553345,-0.8018132756130776,0.4016029509522354,4.993329286903139,-0.2190483838022552,-0.5997337881958207,-1.2118458207692089,-0.7281102878395844,2.0112411668915997,0.10221259161251053,-0.30909872995436094,-0.5631937933047674,1.846413879696845 | 3,477 |
Wormian bones | 6 | 19 | 2.336879 | 0.019445 | Q96AY3,Q04721,O75718,Q32P28,O95831,O75844 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 2,446,261,525,24,122 | 2447,261,122,24,534,1999,2558,2792,2204,446,2390,1754,2147,525,2572,2015,2,2061,2194 | -0.4721097617635663,1.3794214931092326,1.978355565936782,3.264732786733322,0.8352060194424157,-0.23702965284823038,-0.5449466965406411,-0.7097240200629163,-0.34522033918629164,0.972361052266646,-0.43578144422450665,-0.11145955440898236,-0.30909872995436094,0.8523917149803377,-0.5449466965406411,-0.23702965284823038,4.993329286903139,-0.25502527446770934,-0.3271522384422823 | 3,477 |
Mrna transport | 35 | 80 | 2.336087 | 0.019487 | Q07955,Q8TD16,P82979,Q9ULX6,P35658,O60318,Q96FV9,Q86V81,P22626,Q96MU7,Q9UPR3,P49790,Q08J23,Q16629,P49792,P09651,Q96PU8,Q96ST2,Q8NFH4,Q53F19,P37198,Q06787,Q99567,Q9BVL2,Q6I9Y2,O15504,Q9BZI7,Q9BTX1,Q92945,Q8N1F7,Q86U42,P51991,P57740,P41208,P52948 | Processes and pathways | GO Biological process | msigdb_gobp | 258,778,633,140,646,642,926,544,155,927,686,815,295,923,816,812,304,700,439,311,189,824,461,594,199,584,735,484,225,352,862,237,617,374,760 | 3052,2586,1780,2417,584,2610,642,1060,1885,812,939,155,646,189,374,2725,815,816,237,1607,760,617,2771,3196,2952,633,1098,824,258,1642,295,1643,1100,2992,1148,2773,923,311,2324,199,1518,1278,1013,862,544,2009,352,2521,439,2935,778,1672,1365,2402,1412,2295,225,2018,926,2220,927,304,700,461,484,594,1729,1953,735,2872,1440,2708,1840,1489,1599,140,2228,686,3027,2025 | -0.9499890775959331,-0.5631937933047674,-0.1293556878583202,-0.4539381330689716,0.7835773618879034,-0.5814561396181898,0.7145708685502362,0.31394007341810976,-0.18312871527243837,0.541199255452286,0.4190969319876285,1.796769241269738,0.7145708685502362,1.6805731451820296,1.125770842652169,-0.6546590794968076,0.541199255452286,0.541199255452286,1.463421832352514,-0.02218841243594591,0.5933404260508179,0.7490982712358505,-0.6913534327057209,-1.1366911787908272,-0.8572579084205912,0.7318406263618454,0.2963686288929385,0.5237938951093771,1.3962432420799271,-0.04001485370627771,1.278261105136215,-0.04001485370627771,0.2963686288929385,-0.8943015669385899,0.26118655325487,-0.6913534327057209,0.43657813874424445,1.2444526873850936,-0.39951268421354885,1.630619414996261,0.031208258927758886,0.19066452603648326,0.3665765114452106,0.4889454962781681,0.8352060194424157,-0.23702965284823038,1.1767019777664645,-0.5084980423896142,0.9894527093654699,-0.8387603079978073,0.5759724840094101,-0.057855143918590056,0.13763357601742993,-0.43578144422450665,0.10221259161251053,-0.38140051285772825,1.530428347164649,-0.23702965284823038,0.43657813874424445,-0.34522033918629164,0.43657813874424445,1.2613624491146502,0.6626885650713121,0.9552577561979099,0.9210161159169525,0.7835773618879034,-0.09357744939710187,-0.20108142022241898,0.6280391487957254,-0.7833637290550592,0.08448186784031635,-0.6363352046117817,-0.1472658952589451,0.0489797444034831,-0.004375775863415211,1.8629417911591617,-0.34522033918629164,0.6799948733270359,-0.9128477418208648,-0.23702965284823038 | 3,477 |
Prenyltransferase activity | 6 | 12 | 2.335941 | 0.019494 | P37268,Q9Y5Z9,Q86YH6,Q5T2R2,P49356,O95749 | Functions | GO Molecular function | msigdb_gomf | 0,629,715,621,488,125 | 125,1142,1709,0,789,488,1173,621,968,715,1107,629 | 1.945430236375924,0.26118655325487,-0.09357744939710187,5.186433041862088,0.5585921060824289,0.9038777056804731,0.24357584178456979,0.7490982712358505,0.4016029509522354,0.645370002187069,0.2963686288929385,0.7490982712358505 | 3,477 |
Pigment metabolic process | 8 | 29 | 2.329504 | 0.019832 | P30519,P22830,P30536,Q9Y5Y0,P09601,P00813,P33527,O00264 | Processes and pathways | GO Biological process | msigdb_gobp | 5,9,43,188,212,58,123,250 | 250,837,2200,58,3269,3114,2842,212,2762,2926,9,3155,5,43,123,1785,2423,356,2280,1973,2492,3371,1066,1775,3074,485,564,1002,188 | 1.4130541216407417,0.5063759878506557,-0.34522033918629164,2.596605026352921,-1.2683932884585893,-1.0244693677889274,-0.7649300864530652,1.580571395190101,-0.6913534327057209,-0.8387603079978073,4.209496500908907,-1.0805044162419772,4.573593931116834,2.7890650119210334,1.978355565936782,-0.1293556878583202,-0.4539381330689716,1.1597362320078495,-0.38140051285772825,-0.2190483838022552,-0.49029638115367696,-1.5918595006196723,0.31394007341810976,-0.11145955440898236,-0.9685843575272131,0.9210161159169525,0.8180084181768476,0.3840961570394507,1.6972035615388537 | 3,477 |
Slc transporter disorders | 14 | 33 | 2.32293 | 0.020183 | Q9BTX1,P49790,O00400,Q99567,Q9BVL2,P35658,P53985,P52948,P11166,O15504,P57740,Q8NFH4,P37198,Q8N1F7 | Processes and pathways | Reactome Pathways | msigdb_reactome | 484,815,293,461,594,646,238,760,709,584,617,439,189,352 | 293,584,1885,1707,709,939,3145,1604,646,189,815,816,760,238,617,2952,1100,2324,2005,1013,352,2521,439,1672,1365,1412,2018,461,484,594,1729,1440,1599 | 1.278261105136215,0.7835773618879034,-0.18312871527243837,-0.09357744939710187,0.645370002187069,0.4190969319876285,-1.061809293070439,-0.02218841243594591,0.7145708685502362,1.6805731451820296,0.541199255452286,0.541199255452286,0.5933404260508179,1.463421832352514,0.7490982712358505,-0.8572579084205912,0.2963686288929385,-0.39951268421354885,-0.23702965284823038,0.3665765114452106,1.1767019777664645,-0.5084980423896142,0.9894527093654699,-0.057855143918590056,0.13763357601742993,0.10221259161251053,-0.23702965284823038,0.9552577561979099,0.9210161159169525,0.7835773618879034,-0.09357744939710187,0.08448186784031635,-0.004375775863415211 | 3,477 |
Abnormal circulating dicarboxylic acid concentration | 11 | 39 | 2.322228 | 0.020221 | P37268,Q9UJS0,P36551,P41440,Q16134,P48735,P23786,P22695,P40855,P55263,Q9H9P8 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 0,322,356,294,266,327,78,298,246,25,420 | 1021,443,2164,2509,2615,2311,709,1892,2481,3242,1473,3145,2511,298,78,2314,356,0,3032,246,294,3303,327,3068,3132,25,1325,1204,1304,266,2703,1986,1675,420,2370,3025,872,322,1495 | 0.34904397515841284,0.972361052266646,-0.3271522384422823,-0.5084980423896142,-0.5814561396181898,-0.39951268421354885,0.645370002187069,-0.18312871527243837,-0.49029638115367696,-1.230677582860357,0.0489797444034831,-1.061809293070439,-0.5084980423896142,1.2613624491146502,2.3541899251088996,-0.39951268421354885,1.1597362320078495,5.186433041862088,-0.9314102255969627,1.4298541607079167,1.278261105136215,-1.3629900695977135,1.2105997259678525,-0.9685843575272131,-1.0431309642750133,3.264732786733322,0.1553239210492891,0.22595196061218203,0.17300089051442,1.362588845676582,-0.6363352046117817,-0.2190483838022552,-0.057855143918590056,1.0406581721072192,-0.4176396446871264,-0.9128477418208648,0.4889454962781681,1.2275317897751026,0.0489797444034831 | 3,477 |
Sterol binding | 7 | 18 | 2.321358 | 0.020268 | P21796,Q9BZF3,Q14108,P35610,P30536,P45880,Q9H4L5 | Functions | GO Molecular function | msigdb_gomf | 128,7,330,536,43,79,180 | 553,1500,1425,2235,128,2237,1745,43,536,79,3185,330,3377,1077,2154,850,7,180 | 0.8180084181768476,0.031208258927758886,0.08448186784031635,-0.36330308096834,1.9124649794523898,-0.36330308096834,-0.11145955440898236,2.7890650119210334,0.8352060194424157,2.3379546179921205,-1.1179452960132723,1.2105997259678525,-1.61105182439162,0.31394007341810976,-0.30909872995436094,0.5063759878506557,4.573593931116834,1.7138236090436918 | 3,477 |
Organophosphate ester transport | 7 | 29 | 2.321005 | 0.020287 | P08183,O00400,P41440,Q99808,Q14108,Q8WTV0,P33527 | Processes and pathways | GO Biological process | msigdb_gobp | 33,293,294,40,330,19,123 | 293,1197,1349,2789,33,1816,2617,2237,1745,123,294,3457,3185,1610,2594,330,1068,1648,512,2630,2089,1334,19,40,353,850,852,1956,2334 | 1.278261105136215,0.22595196061218203,0.13763357601742993,-0.7097240200629163,3.1544260335844876,-0.1472658952589451,-0.5814561396181898,-0.36330308096834,-0.11145955440898236,1.978355565936782,1.278261105136215,-2.275298022897621,-1.1179452960132723,-0.02218841243594591,-0.5631937933047674,1.2105997259678525,0.31394007341810976,-0.04001485370627771,0.8695655387205098,-0.5814561396181898,-0.2730352960413805,0.1553239210492891,3.4997508506844,2.932574742931529,1.1767019777664645,0.5063759878506557,0.5063759878506557,-0.20108142022241898,-0.39951268421354885 | 3,477 |
Intracellular calcium-sensing protein | 9 | 15 | 2.315564 | 0.020582 | O43852,Q14257,Q02818,P0DP25,Q9BRK5,Q8N163,P80303,P41208,Q8IYU8 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 226,36,101,231,169,139,489,374,351 | 226,231,3461,374,2080,489,101,36,556,2543,1181,351,139,1134,169 | 1.5136927513121756,1.496946485661057,-2.697896024132171,1.125770842652169,-0.2730352960413805,0.9038777056804731,2.1096615598283077,3.1070264246639914,0.8180084181768476,-0.5267147969292446,0.24357584178456979,1.1767019777664645,1.8629417911591617,0.27878413552863,1.7636218040365772 | 3,477 |
Calmodulin | 9 | 15 | 2.315564 | 0.020582 | O43852,Q14257,Q02818,P0DP25,Q9BRK5,Q8N163,P80303,P41208,Q8IYU8 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 226,36,101,231,169,139,489,374,351 | 226,231,3461,374,2080,489,101,36,556,2543,1181,351,139,1134,169 | 1.5136927513121756,1.496946485661057,-2.697896024132171,1.125770842652169,-0.2730352960413805,0.9038777056804731,2.1096615598283077,3.1070264246639914,0.8180084181768476,-0.5267147969292446,0.24357584178456979,1.1767019777664645,1.8629417911591617,0.27878413552863,1.7636218040365772 | 3,477 |
Lipid binding | 28 | 152 | 2.314489 | 0.020641 | P21796,Q9BZF3,P28070,Q9UM22,P04150,Q8WTV0,Q96JM3,Q8NCC3,A6NIH7,O94788,Q9BQE5,P30536,Q15067,Q9NQZ5,Q14677,Q9H4L5,P31749,P37198,O15173,P53367,Q14108,P45880,Q7KZI7,Q13432,P56589,Q5T8D3,P50897,O00264 | Functions | GO Molecular function | msigdb_gomf | 128,7,263,12,389,19,279,153,28,31,164,43,172,427,431,180,183,189,196,72,330,79,468,219,239,364,251,250 | 1403,28,250,1256,896,1059,1966,3212,3076,979,937,553,196,476,2553,2806,2882,757,1470,3128,898,1538,1500,1540,31,1425,3255,1472,1931,2420,389,1742,2201,1141,3400,917,2235,1602,2342,1264,2844,1892,1294,857,3055,2666,1571,2721,128,2237,1745,2826,263,2686,858,2486,43,183,536,189,1120,79,2764,2646,3457,251,1354,2316,2951,72,2567,2794,3314,239,3185,3248,2649,1325,3444,1432,3134,2992,2352,219,2353,2354,588,330,431,3377,1271,2830,172,1514,2539,3059,1694,364,1907,2574,468,1457,949,1649,1104,153,2052,19,1763,2359,3046,3088,279,1132,1077,891,2153,1949,2363,164,2406,2655,2154,850,7,954,1417,180,1226,427,2474,799,1466,1629,2373,1232,1491,564,3090,12,1736,1962,754,914,1401,935,2965,1002,2585,836,688,1536 | 0.10221259161251053,3.217508323661947,1.4130541216407417,0.19066452603648326,0.4540466096167885,0.31394007341810976,-0.2190483838022552,-1.1742341486986292,-0.9871961254841282,0.3840961570394507,0.4190969319876285,0.8180084181768476,1.630619414996261,0.9210161159169525,-0.5449466965406411,-0.7281102878395844,-0.8018132756130776,0.5933404260508179,0.0489797444034831,-1.0431309642750133,0.4540466096167885,0.013423100007657314,0.031208258927758886,0.013423100007657314,3.1702091254103086,0.08448186784031635,-1.2495267166562185,0.0489797444034831,-0.20108142022241898,-0.4539381330689716,1.0747375459534367,-0.11145955440898236,-0.34522033918629164,0.26118655325487,-1.7459284461455995,0.43657813874424445,-0.36330308096834,-0.02218841243594591,-0.4176396446871264,0.19066452603648326,-0.7649300864530652,-0.18312871527243837,0.17300089051442,0.4889454962781681,-0.9499890775959331,-0.6180267920736977,-0.004375775863415211,-0.6546590794968076,1.9124649794523898,-0.36330308096834,-0.11145955440898236,-0.746512291400033,1.3794214931092326,-0.6363352046117817,0.4889454962781681,-0.49029638115367696,2.7890650119210334,1.6972035615388537,0.8352060194424157,1.6805731451820296,0.27878413552863,2.3379546179921205,-0.6913534327057209,-0.5997337881958207,-2.275298022897621,1.4130541216407417,0.13763357601742993,-0.39951268421354885,-0.8572579084205912,2.3866323901235114,-0.5449466965406411,-0.7097240200629163,-1.3819626870605868,1.463421832352514,-1.1179452960132723,-1.230677582860357,-0.5997337881958207,0.1553239210492891,-2.0971723037928203,0.08448186784031635,-1.0431309642750133,-0.8943015669385899,-0.4176396446871264,1.547153301208781,-0.4176396446871264,-0.4176396446871264,0.7835773618879034,1.2105997259678525,1.0065327601008498,-1.61105182439162,0.19066452603648326,-0.746512291400033,1.747032703853092,0.031208258927758886,-0.5267147969292446,-0.9499890775959331,-0.07570932756690205,1.1427591973209943,-0.18312871527243837,-0.5449466965406411,0.938142788391448,0.06673759969946712,0.4190969319876285,-0.04001485370627771,0.2963686288929385,1.8133276304905637,-0.25502527446770934,3.4997508506844,-0.11145955440898236,-0.4176396446871264,-0.9314102255969627,-0.9871961254841282,1.328890738532374,0.27878413552863,0.31394007341810976,0.4715023827975977,-0.30909872995436094,-0.20108142022241898,-0.4176396446871264,1.780200641127462,-0.43578144422450665,-0.5997337881958207,-0.30909872995436094,0.5063759878506557,4.573593931116834,0.4190969319876285,0.10221259161251053,1.7138236090436918,0.22595196061218203,1.0236012369190428,-0.4721097617635663,0.5585921060824289,0.06673759969946712,-0.02218841243594591,-0.4176396446871264,0.22595196061218203,0.0489797444034831,0.8180084181768476,-0.9871961254841282,3.887479702546371,-0.09357744939710187,-0.20108142022241898,0.6106959688336498,0.4540466096167885,0.11992981356626614,0.43657813874424445,-0.8572579084205912,0.3840961570394507,-0.5449466965406411,0.5237938951093771,0.6799948733270359,0.031208258927758886 | 3,477 |
Zinc finger, RanBP2-type superfamily [IPR036443] | 7 | 10 | 2.306652 | 0.021074 | P52756,Q01844,P49790,P35637,Q96EP0,Q92804,P98175 | Sequence | InterPro Superfamily | interpro_homologous_superfamily | 227,445,815,76,747,89,275 | 1472,76,815,816,227,275,445,2469,89,747 | 0.0489797444034831,2.37041584169695,0.541199255452286,0.541199255452286,1.5136927513121756,1.328890738532374,0.972361052266646,-0.4721097617635663,2.2240426346319078,0.6106959688336498 | 3,477 |
Zinc finger, RanBP2-type [IPR001876] | 7 | 10 | 2.306652 | 0.021074 | P52756,Q01844,P49790,P35637,Q96EP0,Q92804,P98175 | Sequence | InterPro Domain | interpro_domain | 227,445,815,76,747,89,275 | 1472,76,815,816,227,275,445,2469,89,747 | 0.0489797444034831,2.37041584169695,0.541199255452286,0.541199255452286,1.5136927513121756,1.328890738532374,0.972361052266646,-0.4721097617635663,2.2240426346319078,0.6106959688336498 | 3,477 |
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