term stringlengths 2 121 | overlap int64 6 281 | setsize int64 7 499 | score float64 1.96 10.6 | pval float64 0 0.05 | edge stringlengths 41 1.97k | type stringclasses 5 values | subtype stringclasses 24 values | subtype_key stringclasses 24 values | edge_idxs stringlengths 11 1.17k | ann_idxs stringlengths 19 2.31k | ann_vals stringlengths 124 9.94k | sig_size int64 2.2k 3.73k |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Anion transport | 28 | 74 | 3.40114 | 0.000671 | P51790,Q9UBX3,Q14728,Q9H2J7,P51798,Q13546,Q6N075,O00400,Q9Y619,P45880,P21796,Q9UHG3,P30825,Q9C0H2,Q96NB2,Q9NZJ7,P07602,P30536,Q8TB61,P41440,P11166,O75746,O75915,Q5T3U5,Q4KMQ2,P08183,Q15043,Q9UJS0 | Processes and pathways | GO Biological process | msigdb_gobp | 132,398,260,272,135,391,267,387,550,29,33,34,298,48,449,581,60,61,320,199,325,454,587,98,479,112,505,250 | 3335,387,2613,2441,2086,2808,3268,770,454,587,2088,1571,1317,1086,1509,60,112,1439,1903,325,880,1038,3450,2337,33,1256,61,298,1515,199,29,132,135,2398,776,2049,652,1325,1718,1161,391,260,3374,505,1400,479,98,267,632,1061,2870,320,449,733,1540,3196,2922,48,1944,699,272,1690,1813,2259,581,398,34,870,250,982,872,2996,550,3084 | -1.3911828140592644,0.8510897924183402,-0.48467366246800686,-0.3953802206575081,-0.22076897182307467,-0.6058872085760314,-1.1847405024855464,0.43002989007773285,0.7546817132763226,0.5820894631601891,-0.22076897182307467,0.004254965933470663,0.11361867633969869,0.22098784106991715,0.03178702145824545,2.757163757995302,2.01913202361103,0.05919085303596074,-0.135372349749194,0.992819324362481,0.35250503124233246,0.24752710744962664,-2.7679958875852217,-0.3365974794064053,3.42971985718421,0.14064504133157937,2.7397803638415104,1.0624319661056087,0.03178702145824545,1.4421732031013788,3.5373871392999625,1.8599120159105682,1.8397070212293376,-0.36591524642575174,0.43002989007773285,-0.19216530124130277,0.5318368798696025,0.11361867633969869,-0.05119875428749204,0.19432848633965574,0.8510897924183402,1.1766660588890563,-1.5329887599381864,0.7058818007064585,0.08646767296946187,0.7303321085557116,2.269128727200785,1.1539946679655793,0.557016627936463,0.24752710744962664,-0.6365864594340644,1.0161145516991787,0.7789314573393142,0.48115289640719744,0.03178702145824545,-0.9853526277263864,-0.6674474549492035,2.9953831789273684,-0.135372349749194,0.5065492848540103,1.1539946679655793,-0.023406543396603797,-0.0791229327418185,-0.2783976197724557,0.6070563074848513,0.8510897924183402,3.42971985718421,0.37846003298308656,1.2217504607212524,0.3002497533746457,0.37846003298308656,-0.7296617004136831,0.6566756516668444,-0.8242407976278554 | 3,477 |
Organic hydroxy compound biosynthetic process | 16 | 56 | 3.387887 | 0.000704 | Q14739,Q15125,O76062,P00374,Q9UBM7,P04035,Q14534,Q15392,Q15800,O76054,P48449,Q13510,Q9BZF3,Q9UKG1,P04062,Q16850 | Processes and pathways | GO Biological process | msigdb_gobp | 224,100,69,90,205,235,300,170,314,86,55,26,59,124,125,95 | 3143,1562,1371,1137,1432,771,519,86,69,913,90,2030,235,125,1508,2970,1510,1087,2619,2562,1042,1256,2216,3171,680,326,1971,55,2908,1656,2575,2737,26,3330,300,224,100,3222,170,1465,314,1100,95,1998,1999,905,3241,2427,59,611,2924,205,870,124,2268,3278 | -0.9203741657960346,0.004254965933470663,0.08646767296946187,0.19432848633965574,0.05919085303596074,0.43002989007773285,0.6813299364803377,2.3995294646169643,2.5631141361485468,0.32643528456534326,2.3625615365785997,-0.19216530124130277,1.2664947720455977,1.8800487114656554,0.03178702145824545,-0.7296617004136831,0.03178702145824545,0.22098784106991715,-0.48467366246800686,-0.45475787720939426,0.24752710744962664,0.14064504133157937,-0.2783976197724557,-0.9527730995631476,0.5065492848540103,0.992819324362481,-0.1637002148171849,2.8261975000437003,-0.6674474549492035,-0.023406543396603797,-0.45475787720939426,-0.5449670887544821,3.658124352450116,-1.3562641561568651,1.0624319661056087,1.3329848954478216,2.250265534513931,-1.0510617648762144,1.6337937661071684,0.05919085303596074,1.0393185235252296,0.22098784106991715,2.30667735249979,-0.1637002148171849,-0.1637002148171849,0.35250503124233246,-1.084195613202823,-0.36591524642575174,2.7744968742488014,0.5820894631601891,-0.6674474549492035,1.4204955543112385,0.37846003298308656,1.900117577201474,-0.2783976197724557,-1.1847405024855464 | 3,477 |
Secondary alcohol metabolic process | 15 | 46 | 3.372326 | 0.000745 | Q14739,Q8WTV0,Q15125,O76062,P05067,Q9UBM7,P04035,Q14534,Q15392,Q15800,O15118,O76054,P48449,P04062,Q16850 | Processes and pathways | GO Biological process | msigdb_gobp | 224,3,100,69,102,205,235,300,170,314,85,86,55,125,95 | 85,2661,771,519,876,86,69,913,2030,235,125,102,2970,1510,1087,3088,750,3271,326,1971,55,564,3172,2512,1781,2908,1656,722,2104,2737,3330,300,224,1985,1212,100,3222,170,1465,314,95,3,2878,694,205,1130 | 2.3995294646169643,-0.5147428618246798,0.43002989007773285,0.6813299364803377,0.35250503124233246,2.3995294646169643,2.5631141361485468,0.32643528456534326,-0.19216530124130277,1.2664947720455977,1.8800487114656554,2.2313425780094427,-0.7296617004136831,0.03178702145824545,0.22098784106991715,-0.8561099941928391,0.45564675544928607,-1.1847405024855464,0.992819324362481,-0.1637002148171849,2.8261975000437003,0.6070563074848513,-0.9527730995631476,-0.42499391779294676,-0.0791229327418185,-0.6674474549492035,-0.023406543396603797,0.48115289640719744,-0.22076897182307467,-0.5449670887544821,-1.3562641561568651,1.0624319661056087,1.3329848954478216,-0.1637002148171849,0.16754792955183684,2.250265534513931,-1.0510617648762144,1.6337937661071684,0.05919085303596074,1.0393185235252296,2.30667735249979,5.112099164366075,-0.6365864594340644,0.5065492848540103,1.4204955543112385,0.22098784106991715 | 3,477 |
Sphingolipid metabolism | 11 | 28 | 3.364939 | 0.000766 | P06865,P16278,O95470,Q06136,P27544,P10619,Q13510,Q96G23,P07602,P04062,Q16739 | Processes and pathways | Reactome Pathways | msigdb_reactome | 198,40,139,44,78,179,26,155,60,125,191 | 835,400,1137,1432,2086,1835,139,125,212,198,60,1572,179,2560,40,369,2562,78,500,44,26,191,3402,155,2648,1748,581,2379 | 0.37846003298308656,0.8271346805755291,0.19432848633965574,0.05919085303596074,-0.22076897182307467,-0.10718036336826706,1.8194332531953932,1.8800487114656554,1.3549837745822957,1.4421732031013788,2.757163757995302,0.004254965933470663,1.5706040688271496,-0.45475787720939426,3.143677150224885,0.8987110224111641,-0.45475787720939426,2.4909615357157167,0.7058818007064585,3.078220375517014,3.658124352450116,1.4852926279143495,-1.6783352899588402,1.7170158615945028,-0.48467366246800686,-0.05119875428749204,0.6070563074848513,-0.3365974794064053 | 3,477 |
Proton transmembrane transporter activity | 18 | 37 | 3.325633 | 0.000882 | P24539,P51790,Q9Y5K8,P36543,Q93050,O75964,Q13423,Q9UDW1,O00400,P48047,P13073,O95202,P00846,O75947,Q9Y487,P56385,P21281,P06576 | Functions | GO Molecular function | msigdb_gomf | 591,132,471,349,72,43,28,142,387,555,297,324,87,433,359,405,623,495 | 387,642,2847,433,43,324,1142,87,1086,495,1639,2209,880,297,2285,845,623,2093,591,1647,2624,957,349,1707,555,132,753,405,2628,1325,28,72,1009,142,1752,359,471 | 0.8510897924183402,0.5318368798696025,-0.6365864594340644,0.7789314573393142,3.078220375517014,0.992819324362481,0.19432848633965574,2.3995294646169643,0.22098784106991715,0.7058818007064585,-0.023406543396603797,-0.2783976197724557,0.35250503124233246,1.0624319661056087,-0.30742542710923365,0.37846003298308656,0.557016627936463,-0.22076897182307467,0.5820894631601891,-0.023406543396603797,-0.48467366246800686,0.3002497533746457,0.9459521537888521,-0.05119875428749204,0.6319180709039718,1.8599120159105682,0.45564675544928607,0.8271346805755291,-0.48467366246800686,0.11361867633969869,3.552612253770201,2.5631141361485468,0.2739473838070137,1.8194332531953932,-0.05119875428749204,0.9459521537888521,0.7546817132763226 | 3,477 |
Dementia | 21 | 61 | 3.310227 | 0.000932 | Q14108,Q13510,P35637,Q96RL7,Q9NZJ7,Q8IY17,O43464,P07602,P06865,P27544,O60313,O15118,P00846,Q9Y487,O76024,P35670,P36543,P05067,P17900,P03886,P04062 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 11,26,403,577,581,444,307,60,198,78,453,85,87,359,588,593,349,102,369,619,125 | 985,85,307,2086,453,1140,588,1437,1142,87,619,2556,125,2333,102,198,60,2208,2037,2560,369,622,1041,954,1842,78,2160,403,593,349,1707,2218,1450,1384,1974,3248,722,1589,886,1979,726,26,11,1399,2411,857,444,1110,1007,1179,1865,1999,577,3240,3241,2482,935,581,797,1241,359 | 0.2739473838070137,2.3995294646169643,1.0393185235252296,-0.22076897182307467,0.7546817132763226,0.19432848633965574,0.5820894631601891,0.05919085303596074,0.19432848633965574,2.3995294646169643,0.557016627936463,-0.45475787720939426,1.8800487114656554,-0.3365974794064053,2.2313425780094427,1.4421732031013788,2.757163757995302,-0.2783976197724557,-0.19216530124130277,-0.45475787720939426,0.8987110224111641,0.557016627936463,0.24752710744962664,0.3002497533746457,-0.10718036336826706,2.4909615357157167,-0.24951260990209947,0.8271346805755291,0.5820894631601891,0.9459521537888521,-0.05119875428749204,-0.2783976197724557,0.05919085303596074,0.08646767296946187,-0.1637002148171849,-1.1175185363069542,0.48115289640719744,0.004254965933470663,0.35250503124233246,-0.1637002148171849,0.48115289640719744,3.658124352450116,4.673528789411234,0.08646767296946187,-0.36591524642575174,0.37846003298308656,0.7789314573393142,0.22098784106991715,0.2739473838070137,0.19432848633965574,-0.10718036336826706,-0.1637002148171849,0.6070563074848513,-1.084195613202823,-1.084195613202823,-0.3953802206575081,0.32643528456534326,0.6070563074848513,0.43002989007773285,0.16754792955183684,0.9459521537888521 | 3,477 |
Intrinsic component of mitochondrial inner membrane | 14 | 33 | 3.291417 | 0.000997 | Q99595,O60830,Q9Y2R0,Q6UXV4,Q9Y512,O75880,Q5XKP0,Q16891,Q13505,Q96NB2,Q15070,Q6P4A7,Q9H3K2,Q9NX63 | Localization | GO Cellular component | msigdb_gocc | 0,1,32,527,336,473,464,463,236,449,182,410,385,257 | 535,1374,1,987,473,2088,1319,2394,3237,1325,236,182,852,463,2116,464,410,527,2244,1281,449,0,2954,385,1690,1188,1813,2264,257,829,32,873,336 | 0.6566756516668444,0.08646767296946187,5.715874196634267,0.2739473838070137,0.7303321085557116,-0.22076897182307467,0.11361867633969869,-0.36591524642575174,-1.084195613202823,0.11361867633969869,1.2664947720455977,1.5493907225373234,0.37846003298308656,0.7546817132763226,-0.22076897182307467,0.7546817132763226,0.8271346805755291,0.6813299364803377,-0.2783976197724557,0.14064504133157937,0.7789314573393142,5.883876178508293,-0.6984719430678344,0.8749483092866545,-0.023406543396603797,0.19432848633965574,-0.0791229327418185,-0.2783976197724557,1.1992511003937982,0.4043013153370249,3.445219269128761,0.37846003298308656,0.992819324362481 | 3,477 |
Membrane lipid biosynthetic process | 8 | 27 | 3.244177 | 0.001178 | Q99805,Q8NBX0,O95470,Q06136,P27544,Q13510,Q96G23,P04062 | Processes and pathways | GO Biological process | msigdb_gobp | 129,101,139,44,78,26,155,125 | 400,1137,1432,769,1830,139,125,1839,2562,78,811,44,26,191,2116,1468,3402,101,1485,1682,155,1351,129,429,1748,768,2379 | 0.8271346805755291,0.19432848633965574,0.05919085303596074,0.43002989007773285,-0.10718036336826706,1.8194332531953932,1.8800487114656554,-0.10718036336826706,-0.45475787720939426,2.4909615357157167,0.4043013153370249,3.078220375517014,3.658124352450116,1.4852926279143495,-0.22076897182307467,0.05919085303596074,-1.6783352899588402,2.250265534513931,0.05919085303596074,-0.023406543396603797,1.7170158615945028,0.11361867633969869,1.8800487114656554,0.8030821726200548,-0.05119875428749204,0.45564675544928607,-0.3365974794064053 | 3,477 |
Active ion transmembrane transporter activity | 20 | 47 | 3.236917 | 0.001208 | P51790,Q9H2J7,P51798,Q9UDW1,O00400,O14548,P20020,P13073,P98194,Q9HD20,Q9Y5K8,P41440,O95202,Q5T3U5,P35670,P36543,P16615,Q15043,P21281,P06576 | Functions | GO Molecular function | msigdb_gomf | 132,272,135,142,387,642,553,297,313,185,471,199,324,98,593,349,621,505,623,495 | 387,642,2441,2847,324,1142,1317,1036,1086,495,1439,1639,2209,880,1038,297,2285,621,553,845,623,2093,1643,2624,1515,593,349,1707,199,132,135,2398,652,2628,313,1325,1718,505,98,1009,2922,272,185,142,1752,872,471 | 0.8510897924183402,0.5318368798696025,-0.3953802206575081,-0.6365864594340644,0.992819324362481,0.19432848633965574,0.11361867633969869,0.24752710744962664,0.22098784106991715,0.7058818007064585,0.05919085303596074,-0.023406543396603797,-0.2783976197724557,0.35250503124233246,0.24752710744962664,1.0624319661056087,-0.30742542710923365,0.557016627936463,0.6319180709039718,0.37846003298308656,0.557016627936463,-0.22076897182307467,-0.023406543396603797,-0.48467366246800686,0.03178702145824545,0.5820894631601891,0.9459521537888521,-0.05119875428749204,1.4421732031013788,1.8599120159105682,1.8397070212293376,-0.36591524642575174,0.5318368798696025,-0.48467366246800686,1.0393185235252296,0.11361867633969869,-0.05119875428749204,0.7058818007064585,2.269128727200785,0.2739473838070137,-0.6674474549492035,1.1539946679655793,1.5281014060315,1.8194332531953932,-0.05119875428749204,0.37846003298308656,0.7546817132763226 | 3,477 |
EF-hand domain [IPR002048] | 19 | 47 | 3.233784 | 0.001222 | Q9UBC2,Q9BRK5,Q8IYU8,Q15293,P80303,O95302,Q14257,Q96AY3,Q9Y680,O95202,O75746,Q02818,Q13813,P0DP25,Q6NUK1,O43852,P41208,Q14651,Q9UJS0 | Sequence | InterPro Domain | interpro_domain | 534,264,268,151,25,31,164,574,63,324,454,83,478,122,632,234,118,503,250 | 1565,234,1434,454,324,31,1770,122,1146,3115,953,1965,1907,2453,3371,118,3091,1776,3123,25,83,1210,1162,478,164,503,151,2355,632,2243,894,268,1482,574,901,692,1807,264,1186,2835,639,2378,534,2545,250,1362,63 | 0.004254965933470663,1.2664947720455977,0.05919085303596074,0.7546817132763226,0.992819324362481,3.4914795286943017,-0.0791229327418185,1.9201190775732102,0.19432848633965574,-0.8881537960438193,0.3002497533746457,-0.1637002148171849,-0.135372349749194,-0.3953802206575081,-1.5329887599381864,1.9797239596761134,-0.8561099941928391,-0.0791229327418185,-0.8881537960438193,3.658124352450116,2.4362702098241025,0.16754792955183684,0.19432848633965574,0.7303321085557116,1.6755503223412216,0.7058818007064585,1.7581944914524472,-0.3365974794064053,0.557016627936463,-0.2783976197724557,0.35250503124233246,1.1539946679655793,0.05919085303596074,0.6070563074848513,0.35250503124233246,0.5065492848540103,-0.0791229327418185,1.1766660588890563,0.19432848633965574,-0.6058872085760314,0.557016627936463,-0.3365974794064053,0.6813299364803377,-0.42499391779294676,1.2217504607212524,0.11361867633969869,2.7397803638415104 | 3,477 |
Anion transmembrane transporter activity | 19 | 51 | 3.187563 | 0.001435 | P51790,Q9UBX3,Q14728,P51798,Q6N075,O00400,P45880,P21796,P30825,Q9C0H2,Q96NB2,Q8TB61,P41440,P11166,O75746,Q5T3U5,Q4KMQ2,Q15043,Q9UJS0 | Functions | GO Molecular function | msigdb_gomf | 132,398,260,135,267,387,29,33,298,48,449,320,199,325,454,98,479,505,250 | 3335,387,2613,2441,2086,2808,454,2088,1317,1086,1439,1903,325,880,1038,33,298,1515,199,29,132,135,2398,776,652,1718,260,505,1400,479,98,267,632,1061,2870,320,449,733,1540,3196,2922,48,699,1690,1813,398,250,982,872,550,3084 | -1.3911828140592644,0.8510897924183402,-0.48467366246800686,-0.3953802206575081,-0.22076897182307467,-0.6058872085760314,0.7546817132763226,-0.22076897182307467,0.11361867633969869,0.22098784106991715,0.05919085303596074,-0.135372349749194,0.992819324362481,0.35250503124233246,0.24752710744962664,3.42971985718421,1.0624319661056087,0.03178702145824545,1.4421732031013788,3.5373871392999625,1.8599120159105682,1.8397070212293376,-0.36591524642575174,0.43002989007773285,0.5318368798696025,-0.05119875428749204,1.1766660588890563,0.7058818007064585,0.08646767296946187,0.7303321085557116,2.269128727200785,1.1539946679655793,0.557016627936463,0.24752710744962664,-0.6365864594340644,1.0161145516991787,0.7789314573393142,0.48115289640719744,0.03178702145824545,-0.9853526277263864,-0.6674474549492035,2.9953831789273684,0.5065492848540103,-0.023406543396603797,-0.0791229327418185,0.8510897924183402,1.2217504607212524,0.3002497533746457,0.37846003298308656,0.6566756516668444,-0.8242407976278554 | 3,477 |
Glycoside hydrolase superfamily [IPR017853] | 7 | 15 | 3.18354 | 0.001455 | P06865,P16278,O60502,Q9BTY2,P10253,P54802,P04062 | Sequence | InterPro Superfamily | interpro_homologous_superfamily | 198,40,106,169,202,94,125 | 106,125,717,212,198,1572,1439,1961,202,40,2675,94,2110,169,1611 | 2.097175457160336,1.8800487114656554,0.48115289640719744,1.3549837745822957,1.4421732031013788,0.004254965933470663,0.05919085303596074,-0.1637002148171849,1.4204955543112385,3.143677150224885,-0.5147428618246798,2.325363541577442,-0.22076897182307467,1.654708681534299,0.004254965933470663 | 3,477 |
Vacuolar membrane | 45 | 130 | 3.183176 | 0.001457 | Q9H270,Q8WTV0,Q9H2V7,P51790,P11117,P42785,P21281,Q14108,P51798,Q9UNK0,O75503,Q9H444,P51809,Q9UIQ6,Q9BTU6,Q99523,P10619,Q96RL7,P42892,Q9NZJ7,Q15382,P07602,Q9Y5K8,P41440,Q93050,Q9HBH5,P10253,Q8N511,Q9HD42,O15118,Q07065,Q8TCT8,Q9Y487,O75787,Q16625,Q5T3U5,P36543,O75955,Q7Z3C6,Q8NCG7,Q92542,Q15043,Q9NQX7,P04062,Q8IV08 | Localization | GO Cellular component | msigdb_gocc | 666,3,130,132,131,7,623,11,135,417,20,293,539,39,558,175,179,577,53,581,441,60,471,199,72,466,202,79,210,85,458,89,359,586,225,98,349,347,364,634,244,505,386,125,126 | 1368,2771,85,948,2149,2024,1080,3168,1140,2847,20,586,347,1899,772,2668,125,1203,1438,60,1379,3065,1439,2034,644,2152,202,179,131,2038,1772,2157,623,2093,2934,956,1089,349,1707,1153,199,1154,7,53,2161,1519,2681,132,135,539,1712,1159,2515,1260,2342,2628,2856,3273,2346,2686,2785,458,2860,962,2739,1787,11,1985,505,441,225,98,855,364,126,2870,1799,79,2831,634,1482,89,3,2061,1939,244,72,1737,1286,2425,662,2646,1999,577,175,2428,558,3474,1689,2598,1123,737,1416,2257,666,130,293,2880,466,2259,210,386,1879,581,827,2379,1550,1236,1752,39,2886,2607,417,1241,1364,1556,983,359,471,1694 | 0.08646767296946187,-0.575347982490337,2.3995294646169643,0.3002497533746457,-0.24951260990209947,-0.19216530124130277,0.22098784106991715,-0.9527730995631476,0.19432848633965574,-0.6365864594340644,3.935544376605113,0.5820894631601891,0.9459521537888521,-0.135372349749194,0.43002989007773285,-0.5147428618246798,1.8800487114656554,0.16754792955183684,0.05919085303596074,2.757163757995302,0.08646767296946187,-0.8242407976278554,0.05919085303596074,-0.19216530124130277,0.5318368798696025,-0.24951260990209947,1.4204955543112385,1.5706040688271496,1.8599120159105682,-0.19216530124130277,-0.0791229327418185,-0.24951260990209947,0.557016627936463,-0.22076897182307467,-0.6984719430678344,0.3002497533746457,0.22098784106991715,0.9459521537888521,-0.05119875428749204,0.19432848633965574,1.4421732031013788,0.19432848633965574,4.93319079393823,2.8944454237079458,-0.24951260990209947,0.03178702145824545,-0.5147428618246798,1.8599120159105682,1.8397070212293376,0.6566756516668444,-0.05119875428749204,0.19432848633965574,-0.42499391779294676,0.14064504133157937,-0.3365974794064053,-0.48467366246800686,-0.6365864594340644,-1.1847405024855464,-0.3365974794064053,-0.5147428618246798,-0.575347982490337,0.7546817132763226,-0.6365864594340644,0.3002497533746457,-0.5449670887544821,-0.0791229327418185,4.673528789411234,-0.1637002148171849,0.7058818007064585,0.7789314573393142,1.3329848954478216,2.269128727200785,0.37846003298308656,0.9223787132780272,1.8800487114656554,-0.6365864594340644,-0.0791229327418185,2.4909615357157167,-0.6058872085760314,0.557016627936463,0.05919085303596074,2.3810740774224746,5.112099164366075,-0.19216530124130277,-0.135372349749194,1.244164800335857,2.5631141361485468,-0.05119875428749204,0.14064504133157937,-0.36591524642575174,0.5318368798696025,-0.48467366246800686,-0.1637002148171849,0.6070563074848513,1.612805048617125,-0.36591524642575174,0.6319180709039718,-7.011067236704793,-0.023406543396603797,-0.45475787720939426,0.22098784106991715,0.48115289640719744,0.08646767296946187,-0.2783976197724557,0.5318368798696025,1.8800487114656554,1.0854555970140953,-0.6365864594340644,0.7546817132763226,-0.2783976197724557,1.3769014390666614,0.8749483092866545,-0.10718036336826706,0.6070563074848513,0.4043013153370249,-0.3365974794064053,0.03178702145824545,0.16754792955183684,-0.05119875428749204,3.176140028658313,-0.6365864594340644,-0.45475787720939426,0.8271346805755291,0.16754792955183684,0.11361867633969869,0.03178702145824545,0.3002497533746457,0.9459521537888521,0.7546817132763226,-0.023406543396603797 | 3,477 |
Liposaccharide metabolic process | 7 | 18 | 3.170335 | 0.001523 | Q99805,Q8NBX0,P06865,P16278,P06280,P04062,Q16739 | Processes and pathways | GO Biological process | msigdb_gobp | 129,101,198,40,212,125,191 | 769,1830,125,717,212,198,1572,40,369,811,1457,191,1468,101,1485,1682,1351,129 | 0.43002989007773285,-0.10718036336826706,1.8800487114656554,0.48115289640719744,1.3549837745822957,1.4421732031013788,0.004254965933470663,3.143677150224885,0.8987110224111641,0.4043013153370249,0.05919085303596074,1.4852926279143495,0.05919085303596074,2.250265534513931,0.05919085303596074,-0.023406543396603797,0.11361867633969869,1.8800487114656554 | 3,477 |
Abnormality of hepatobiliary system physiology | 30 | 85 | 3.156001 | 0.001599 | P22830,O75845,O43772,Q9Y619,Q13510,P11310,O15460,P56589,Q01130,Q9BT22,O95169,P22695,Q9NWS8,P34949,P23786,P40855,Q00059,P38571,Q5XKP0,Q8N511,Q96A33,O15118,P00846,A2RRP1,O75381,O75787,Q16625,P35670,P50416,P04062 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 499,519,22,550,26,280,157,163,541,424,42,554,304,311,310,319,437,189,464,79,342,85,87,337,585,586,225,593,594,125 | 337,85,157,22,1374,1831,843,585,586,519,42,2811,2089,87,1766,619,2556,125,1253,2814,1639,1254,280,2898,2449,554,499,310,1256,311,593,2288,2727,189,3336,1153,319,1708,2290,1846,594,2732,3045,3238,2298,163,1716,3151,437,541,848,998,26,2110,3239,225,1100,853,464,966,1169,1171,79,898,2421,342,2875,2249,1487,424,3417,933,1493,766,304,2926,1818,2015,2804,1886,1823,1306,2019,944,550 | 0.9694321064173009,2.3995294646169643,1.6963192103002542,3.834814628505806,0.08646767296946187,-0.10718036336826706,0.37846003298308656,0.5820894631601891,0.5820894631601891,0.6813299364803377,3.094651561884198,-0.6058872085760314,-0.22076897182307467,2.3995294646169643,-0.0791229327418185,0.557016627936463,-0.45475787720939426,1.8800487114656554,0.14064504133157937,-0.6058872085760314,-0.023406543396603797,0.14064504133157937,1.1083901252715689,-0.6674474549492035,-0.3953802206575081,0.6319180709039718,0.7058818007064585,1.0393185235252296,0.14064504133157937,1.0393185235252296,0.5820894631601891,-0.30742542710923365,-0.5449670887544821,1.4852926279143495,-1.3911828140592644,0.19432848633965574,1.0161145516991787,-0.05119875428749204,-0.30742542710923365,-0.10718036336826706,0.5820894631601891,-0.5449670887544821,-0.7925442764842194,-1.084195613202823,-0.30742542710923365,1.6755503223412216,-0.05119875428749204,-0.9203741657960346,0.7789314573393142,0.6566756516668444,0.37846003298308656,0.2739473838070137,3.658124352450116,-0.22076897182307467,-1.084195613202823,1.3329848954478216,0.22098784106991715,0.37846003298308656,0.7546817132763226,0.3002497533746457,0.19432848633965574,0.19432848633965574,2.4909615357157167,0.35250503124233246,-0.36591524642575174,0.9694321064173009,-0.6365864594340644,-0.2783976197724557,0.05919085303596074,0.8030821726200548,-1.7897795234170681,0.32643528456534326,0.05919085303596074,0.45564675544928607,1.0624319661056087,-0.6674474549492035,-0.0791229327418185,-0.1637002148171849,-0.575347982490337,-0.10718036336826706,-0.0791229327418185,0.14064504133157937,-0.1637002148171849,0.32643528456534326,0.6566756516668444 | 3,477 |
Proton transporting two sector atpase complex | 15 | 24 | 3.144827 | 0.001662 | P24539,P36543,Q9Y5K8,Q93050,O75964,Q96IX5,P48047,Q8N511,Q15904,P00846,O75947,Q9Y487,P56385,O75787,P06576 | Localization | GO Cellular component | msigdb_gocc | 591,349,471,72,43,422,555,79,442,87,433,359,405,586,495 | 2847,586,433,43,87,495,623,2093,591,1647,957,349,1707,555,753,405,2628,442,79,72,422,1752,359,471 | -0.6365864594340644,0.5820894631601891,0.7789314573393142,3.078220375517014,2.3995294646169643,0.7058818007064585,0.557016627936463,-0.22076897182307467,0.5820894631601891,-0.023406543396603797,0.3002497533746457,0.9459521537888521,-0.05119875428749204,0.6319180709039718,0.45564675544928607,0.8271346805755291,-0.48467366246800686,0.7789314573393142,2.4909615357157167,2.5631141361485468,0.8030821726200548,-0.05119875428749204,0.9459521537888521,0.7546817132763226 | 3,477 |
Tetrapyrrole binding | 8 | 17 | 3.143203 | 0.001671 | Q8WUJ1,O15173,P30519,O43169,P09601,P53701,Q16850,Q6UW02 | Functions | GO Molecular function | msigdb_gomf | 67,134,13,51,52,181,95,192 | 836,134,51,1639,52,2899,13,181,95,192,67,341,484,1489,201,2376,834 | 0.37846003298308656,1.8397070212293376,2.8944454237079458,-0.023406543396603797,2.8944454237079458,-0.6674474549492035,4.622785168296892,1.5493907225373234,2.30667735249979,1.4852926279143495,2.634407263051025,0.9694321064173009,0.7303321085557116,0.05919085303596074,1.4421732031013788,-0.3365974794064053,0.4043013153370249 | 3,477 |
EF-hand domain pair [IPR011992] | 19 | 52 | 3.130953 | 0.001742 | Q9UBC2,Q9BRK5,Q8IYU8,Q15293,P80303,O95302,Q14257,Q96AY3,Q9Y680,O95202,O75746,Q02818,Q13813,P0DP25,Q6NUK1,O43852,P41208,Q14651,Q9UJS0 | Sequence | InterPro Superfamily | interpro_homologous_superfamily | 534,264,268,151,25,31,164,574,63,324,454,83,478,122,632,234,118,503,250 | 1565,234,1434,454,324,31,1770,122,1146,3115,953,1965,1907,2449,2453,3371,118,3091,1776,992,3123,25,83,1210,1162,478,164,503,151,2355,632,927,2243,894,268,1676,1482,574,901,692,1807,264,1186,2835,2258,639,2378,534,2545,250,1362,63 | 0.004254965933470663,1.2664947720455977,0.05919085303596074,0.7546817132763226,0.992819324362481,3.4914795286943017,-0.0791229327418185,1.9201190775732102,0.19432848633965574,-0.8881537960438193,0.3002497533746457,-0.1637002148171849,-0.135372349749194,-0.3953802206575081,-0.3953802206575081,-1.5329887599381864,1.9797239596761134,-0.8561099941928391,-0.0791229327418185,0.2739473838070137,-0.8881537960438193,3.658124352450116,2.4362702098241025,0.16754792955183684,0.19432848633965574,0.7303321085557116,1.6755503223412216,0.7058818007064585,1.7581944914524472,-0.3365974794064053,0.557016627936463,0.32643528456534326,-0.2783976197724557,0.35250503124233246,1.1539946679655793,-0.023406543396603797,0.05919085303596074,0.6070563074848513,0.35250503124233246,0.5065492848540103,-0.0791229327418185,1.1766660588890563,0.19432848633965574,-0.6058872085760314,-0.2783976197724557,0.557016627936463,-0.3365974794064053,0.6813299364803377,-0.42499391779294676,1.2217504607212524,0.11361867633969869,2.7397803638415104 | 3,477 |
Alcohol biosynthetic process | 13 | 38 | 3.099519 | 0.001938 | Q14739,Q15125,O76062,P00374,Q9UBM7,P04035,Q15392,Q15800,O76054,P48449,Q13510,P04062,Q16850 | Processes and pathways | GO Biological process | msigdb_gobp | 224,100,69,90,205,235,170,314,86,55,26,125,95 | 3143,1137,1432,771,519,86,69,913,90,2030,235,125,2970,1510,1087,2619,2216,680,326,1971,55,2908,1656,2575,2737,26,3330,224,100,3222,170,1465,314,1100,95,3241,2924,205 | -0.9203741657960346,0.19432848633965574,0.05919085303596074,0.43002989007773285,0.6813299364803377,2.3995294646169643,2.5631141361485468,0.32643528456534326,2.3625615365785997,-0.19216530124130277,1.2664947720455977,1.8800487114656554,-0.7296617004136831,0.03178702145824545,0.22098784106991715,-0.48467366246800686,-0.2783976197724557,0.5065492848540103,0.992819324362481,-0.1637002148171849,2.8261975000437003,-0.6674474549492035,-0.023406543396603797,-0.45475787720939426,-0.5449670887544821,3.658124352450116,-1.3562641561568651,1.3329848954478216,2.250265534513931,-1.0510617648762144,1.6337937661071684,0.05919085303596074,1.0393185235252296,0.22098784106991715,2.30667735249979,-1.084195613202823,-0.6674474549492035,1.4204955543112385 | 3,477 |
Steroid binding | 7 | 24 | 3.096157 | 0.00196 | P21796,Q14108,P45880,O15118,P04062,Q9BZF3,P30536 | Functions | GO Molecular function | msigdb_gomf | 33,11,29,85,125,59,61 | 836,85,134,771,913,125,1507,1036,3065,33,2562,1042,61,3271,361,29,722,11,1985,905,2755,487,59,611 | 0.37846003298308656,2.3995294646169643,1.8397070212293376,0.43002989007773285,0.32643528456534326,1.8800487114656554,0.03178702145824545,0.24752710744962664,-0.8242407976278554,3.42971985718421,-0.45475787720939426,0.24752710744962664,2.7397803638415104,-1.1847405024855464,0.9223787132780272,3.5373871392999625,0.48115289640719744,4.673528789411234,-0.1637002148171849,0.35250503124233246,-0.5449670887544821,0.7303321085557116,2.7744968742488014,0.5820894631601891 | 3,477 |
Inorganic anion transport | 8 | 30 | 3.095794 | 0.001963 | P21796,Q9UHG3,Q5T3U5,P51790,Q9C0H2,P08183,P30536,P45880 | Processes and pathways | GO Biological process | msigdb_gobp | 33,34,98,132,48,112,61,29 | 3335,2441,2086,1317,112,1903,33,61,1515,29,132,135,2049,652,1325,1718,505,479,98,267,2870,733,2922,48,1944,398,34,982,872,3084 | -1.3911828140592644,-0.3953802206575081,-0.22076897182307467,0.11361867633969869,2.01913202361103,-0.135372349749194,3.42971985718421,2.7397803638415104,0.03178702145824545,3.5373871392999625,1.8599120159105682,1.8397070212293376,-0.19216530124130277,0.5318368798696025,0.11361867633969869,-0.05119875428749204,0.7058818007064585,0.7303321085557116,2.269128727200785,1.1539946679655793,-0.6365864594340644,0.48115289640719744,-0.6674474549492035,2.9953831789273684,-0.135372349749194,0.8510897924183402,3.42971985718421,0.3002497533746457,0.37846003298308656,-0.8242407976278554 | 3,477 |
primary active transporter | 12 | 26 | 3.086644 | 0.002024 | O60888,Q9GZP9,P35670,Q6NTF9,Q9H2J7,P20020,Q9NS69,Q96NB2,P98194,Q6P4A7,Q8N4H5,O75381 | Functions | Panther Protein class | panther_protein_class | 65,196,593,602,272,553,19,449,313,410,88,585 | 65,585,1377,1437,1036,2775,806,621,553,1643,593,2165,313,1526,1400,602,410,88,2831,449,2065,196,272,1690,1745,19 | 2.669737999799437,0.5820894631601891,0.08646767296946187,0.05919085303596074,0.24752710744962664,-0.575347982490337,0.4043013153370249,0.557016627936463,0.6319180709039718,-0.023406543396603797,0.5820894631601891,-0.24951260990209947,1.0393185235252296,0.03178702145824545,0.08646767296946187,0.5820894631601891,0.8271346805755291,2.3995294646169643,-0.6058872085760314,0.7789314573393142,-0.19216530124130277,1.463772033506031,1.1539946679655793,-0.023406543396603797,-0.05119875428749204,4.0765911800980605 | 3,477 |
Ion channel transport | 16 | 32 | 3.074536 | 0.002108 | Q4KMQ2,P51790,Q9Y5K8,P35670,P36543,Q93050,P51798,Q13546,P20020,Q9C0H2,Q15904,P98194,P16615,Q9HD20,Q9Y487,Q99576 | Processes and pathways | Reactome Pathways | msigdb_reactome | 479,132,471,593,349,72,135,391,553,48,442,313,621,185,359,384 | 2847,1036,621,553,623,2093,1643,2453,593,349,1707,132,135,2165,2628,313,887,391,1665,2406,442,479,2831,72,1685,384,48,1015,185,1752,359,471 | -0.6365864594340644,0.24752710744962664,0.557016627936463,0.6319180709039718,0.557016627936463,-0.22076897182307467,-0.023406543396603797,-0.3953802206575081,0.5820894631601891,0.9459521537888521,-0.05119875428749204,1.8599120159105682,1.8397070212293376,-0.24951260990209947,-0.48467366246800686,1.0393185235252296,0.35250503124233246,0.8510897924183402,-0.023406543396603797,-0.36591524642575174,0.7789314573393142,0.7303321085557116,-0.6058872085760314,2.5631141361485468,-0.023406543396603797,0.8749483092866545,2.9953831789273684,0.2739473838070137,1.5281014060315,-0.05119875428749204,0.9459521537888521,0.7546817132763226 | 3,477 |
EF-Hand 1, calcium-binding site [IPR018247] | 17 | 40 | 3.061669 | 0.002201 | Q13813,Q14257,Q9UBC2,Q9BRK5,Q6NUK1,O43852,O95202,Q14651,O75746,Q02818,P41208,Q15293,P80303,P0DP25,Q96AY3,Q9Y680,O95302 | Sequence | InterPro Binding site | interpro_binding_site | 478,164,534,264,632,234,324,503,454,83,118,151,25,122,574,63,31 | 1565,234,1434,454,324,31,1770,122,1146,3115,953,1965,1907,2453,3371,118,3091,1776,25,83,1210,478,164,503,151,632,2243,894,574,692,1807,264,1186,2835,639,2378,534,2545,1362,63 | 0.004254965933470663,1.2664947720455977,0.05919085303596074,0.7546817132763226,0.992819324362481,3.4914795286943017,-0.0791229327418185,1.9201190775732102,0.19432848633965574,-0.8881537960438193,0.3002497533746457,-0.1637002148171849,-0.135372349749194,-0.3953802206575081,-1.5329887599381864,1.9797239596761134,-0.8561099941928391,-0.0791229327418185,3.658124352450116,2.4362702098241025,0.16754792955183684,0.7303321085557116,1.6755503223412216,0.7058818007064585,1.7581944914524472,0.557016627936463,-0.2783976197724557,0.35250503124233246,0.6070563074848513,0.5065492848540103,-0.0791229327418185,1.1766660588890563,0.19432848633965574,-0.6058872085760314,0.557016627936463,-0.3365974794064053,0.6813299364803377,-0.42499391779294676,0.11361867633969869,2.7397803638415104 | 3,477 |
Steroid biosynthesis | 10 | 23 | 3.011829 | 0.002597 | Q14739,Q53GQ0,O76062,Q15125,Q9UBM7,P04035,Q15392,Q15800,P48449,Q16850 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 224,165,69,100,205,235,170,314,55,95 | 519,69,2030,235,1510,326,55,1656,2737,3330,224,100,3222,170,1465,314,95,165,1731,1294,2485,205,870 | 0.6813299364803377,2.5631141361485468,-0.19216530124130277,1.2664947720455977,0.03178702145824545,0.992819324362481,2.8261975000437003,-0.023406543396603797,-0.5449670887544821,-1.3562641561568651,1.3329848954478216,2.250265534513931,-1.0510617648762144,1.6337937661071684,0.05919085303596074,1.0393185235252296,2.30667735249979,1.6755503223412216,-0.05119875428749204,0.14064504133157937,-0.3953802206575081,1.4204955543112385,0.37846003298308656 | 3,477 |
membrane trafficking regulatory protein | 6 | 22 | 3.010002 | 0.002612 | O43760,Q13439,Q8WTV0,Q14108,O43731,P24390 | Functions | Panther Protein class | panther_protein_class | 159,352,3,11,75,27 | 2806,837,838,75,159,1835,1772,27,352,11,630,2351,3,1006,1535,1737,374,1416,666,2761,2379,1550 | -0.6058872085760314,0.37846003298308656,0.37846003298308656,2.5271465892925953,1.6963192103002542,-0.10718036336826706,-0.0791229327418185,3.6431638120553607,0.9459521537888521,4.673528789411234,0.557016627936463,-0.3365974794064053,5.112099164366075,0.2739473838070137,0.03178702145824545,-0.05119875428749204,0.8987110224111641,0.08646767296946187,0.5318368798696025,-0.5449670887544821,-0.3365974794064053,0.03178702145824545 | 3,477 |
Serine hydrolase activity | 8 | 20 | 3.006575 | 0.002642 | P42785,Q9H3G5,Q9HB40,Q16740,P10619,P67812,O43464,O14773 | Functions | GO Molecular function | msigdb_gomf | 7,15,16,113,179,312,307,221 | 221,307,360,179,3116,2451,1651,7,3071,1386,883,312,113,1530,854,602,818,2473,15,16 | 1.3329848954478216,1.0393185235252296,0.9223787132780272,1.5706040688271496,-0.8881537960438193,-0.3953802206575081,-0.023406543396603797,4.93319079393823,-0.8242407976278554,0.08646767296946187,0.35250503124233246,1.0393185235252296,2.01913202361103,0.03178702145824545,0.37846003298308656,0.5820894631601891,0.4043013153370249,-0.3953802206575081,4.362495893754808,4.173401607815876 | 3,477 |
Hepatic failure | 19 | 51 | 3.004901 | 0.002657 | P22830,O75845,O43772,Q9Y619,Q13510,O15460,P56589,P34949,P23786,P40855,Q00059,P38571,O15118,P00846,A2RRP1,O75381,P35670,P50416,P04062 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 499,519,22,550,26,157,163,311,310,319,437,189,85,87,337,585,593,594,125 | 337,85,157,22,1831,585,519,2811,2089,87,1766,619,2556,125,1253,2814,1639,1254,2898,499,310,1256,311,593,189,3336,319,1708,2290,594,3045,163,3151,437,848,998,26,1100,853,966,1169,2249,1487,1493,2926,1818,2015,2804,1306,944,550 | 0.9694321064173009,2.3995294646169643,1.6963192103002542,3.834814628505806,-0.10718036336826706,0.5820894631601891,0.6813299364803377,-0.6058872085760314,-0.22076897182307467,2.3995294646169643,-0.0791229327418185,0.557016627936463,-0.45475787720939426,1.8800487114656554,0.14064504133157937,-0.6058872085760314,-0.023406543396603797,0.14064504133157937,-0.6674474549492035,0.7058818007064585,1.0393185235252296,0.14064504133157937,1.0393185235252296,0.5820894631601891,1.4852926279143495,-1.3911828140592644,1.0161145516991787,-0.05119875428749204,-0.30742542710923365,0.5820894631601891,-0.7925442764842194,1.6755503223412216,-0.9203741657960346,0.7789314573393142,0.37846003298308656,0.2739473838070137,3.658124352450116,0.22098784106991715,0.37846003298308656,0.3002497533746457,0.19432848633965574,-0.2783976197724557,0.05919085303596074,0.05919085303596074,-0.6674474549492035,-0.0791229327418185,-0.1637002148171849,-0.575347982490337,0.14064504133157937,0.32643528456534326,0.6566756516668444 | 3,477 |
Electron transport chain oxphos system in mitochondria | 24 | 53 | 3.001582 | 0.002686 | P14927,Q9UDW1,O14548,P14406,P56385,O95169,O75964,P22695,P48047,P13073,O75947,Q9UII2,O43676,O95168,O14949,P00846,O95299,O96000,O43674,P24539,O75880,Q16795,P03886,P06576 | Processes and pathways | WikiPathways | msigdb_wp | 140,142,642,24,405,42,43,554,555,297,433,335,68,561,452,87,714,716,222,591,473,756,619,495 | 1369,642,452,222,68,3409,911,1832,843,2026,1251,473,433,43,561,42,2664,714,716,1142,87,619,2556,1086,495,2209,880,1038,297,24,2285,140,1642,2212,845,1041,554,591,1647,2902,2160,2624,957,555,2570,2297,753,405,3020,756,142,335,946 | 0.08646767296946187,0.5318368798696025,0.7546817132763226,1.3329848954478216,2.598866826737196,-1.7523935642470363,0.32643528456534326,-0.10718036336826706,0.37846003298308656,-0.19216530124130277,0.14064504133157937,0.7303321085557116,0.7789314573393142,3.078220375517014,0.6070563074848513,3.094651561884198,-0.5147428618246798,0.48115289640719744,0.48115289640719744,0.19432848633965574,2.3995294646169643,0.557016627936463,-0.45475787720939426,0.22098784106991715,0.7058818007064585,-0.2783976197724557,0.35250503124233246,0.24752710744962664,1.0624319661056087,3.732375271475552,-0.30742542710923365,1.8194332531953932,-0.023406543396603797,-0.2783976197724557,0.37846003298308656,0.24752710744962664,0.6319180709039718,0.5820894631601891,-0.023406543396603797,-0.6674474549492035,-0.24951260990209947,-0.48467366246800686,0.3002497533746457,0.6319180709039718,-0.45475787720939426,-0.30742542710923365,0.45564675544928607,0.8271346805755291,-0.7610185329208947,0.45564675544928607,1.8194332531953932,0.992819324362481,0.32643528456534326 | 3,477 |
Protein insertion into membrane | 8 | 28 | 2.994609 | 0.002748 | O14737,Q9Y512,P46379,Q9NS69,Q96A33,Q15070,Q8N4V1,Q15629 | Processes and pathways | GO Biological process | msigdb_gobp | 316,336,50,19,342,182,284,58 | 316,1079,2086,1032,1377,2282,2287,2778,50,1658,1457,371,182,58,2116,1469,1727,284,1533,2244,2365,342,19,704,3256,1823,336,1953 | 1.0161145516991787,0.22098784106991715,-0.22076897182307467,0.24752710744962664,0.08646767296946187,-0.30742542710923365,-0.30742542710923365,-0.575347982490337,2.961925562747231,-0.023406543396603797,0.05919085303596074,0.8987110224111641,1.5493907225373234,2.7917800083518514,-0.22076897182307467,0.05919085303596074,-0.05119875428749204,1.1083901252715689,0.03178702145824545,-0.2783976197724557,-0.3365974794064053,0.9694321064173009,4.0765911800980605,0.5065492848540103,-1.1175185363069542,-0.0791229327418185,0.992819324362481,-0.135372349749194 | 3,477 |
Mental deterioration | 22 | 102 | 2.990264 | 0.002787 | Q14108,O95470,O75503,Q13510,P35637,P50897,P16278,O95169,Q8IY17,O43464,P07602,P06865,Q5XKP0,P27544,O15118,P00846,Q9Y487,P54802,P36543,P05067,P17900,P04062 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 11,139,20,26,403,36,40,42,444,307,60,198,464,78,85,87,359,94,349,102,369,125 | 985,85,307,2086,1374,453,1249,1140,843,20,588,2662,42,139,1437,1142,87,619,2556,125,2333,102,198,60,1572,1902,2208,2037,1145,2285,2560,40,844,369,2620,622,1041,646,954,1842,78,2160,403,593,349,1707,1846,2218,1450,2625,36,3247,1384,94,1974,3248,722,1659,2686,683,1589,2785,886,3094,848,2230,1979,726,26,11,1399,2307,2411,464,1791,2526,857,444,1110,1007,1734,1179,1865,904,1999,577,3240,3241,2482,2427,694,3417,3312,934,935,2009,581,797,2196,1425,1241,359 | 0.2739473838070137,2.3995294646169643,1.0393185235252296,-0.22076897182307467,0.08646767296946187,0.7546817132763226,0.14064504133157937,0.19432848633965574,0.37846003298308656,3.935544376605113,0.5820894631601891,-0.5147428618246798,3.094651561884198,1.8194332531953932,0.05919085303596074,0.19432848633965574,2.3995294646169643,0.557016627936463,-0.45475787720939426,1.8800487114656554,-0.3365974794064053,2.2313425780094427,1.4421732031013788,2.757163757995302,0.004254965933470663,-0.135372349749194,-0.2783976197724557,-0.19216530124130277,0.19432848633965574,-0.30742542710923365,-0.45475787720939426,3.143677150224885,0.37846003298308656,0.8987110224111641,-0.48467366246800686,0.557016627936463,0.24752710744962664,0.5318368798696025,0.3002497533746457,-0.10718036336826706,2.4909615357157167,-0.24951260990209947,0.8271346805755291,0.5820894631601891,0.9459521537888521,-0.05119875428749204,-0.10718036336826706,-0.2783976197724557,0.05919085303596074,-0.48467366246800686,3.2565382958940745,-1.1175185363069542,0.08646767296946187,2.325363541577442,-0.1637002148171849,-1.1175185363069542,0.48115289640719744,-0.023406543396603797,-0.5147428618246798,0.5065492848540103,0.004254965933470663,-0.575347982490337,0.35250503124233246,-0.8561099941928391,0.37846003298308656,-0.2783976197724557,-0.1637002148171849,0.48115289640719744,3.658124352450116,4.673528789411234,0.08646767296946187,-0.30742542710923365,-0.36591524642575174,0.7546817132763226,-0.0791229327418185,-0.42499391779294676,0.37846003298308656,0.7789314573393142,0.22098784106991715,0.2739473838070137,-0.05119875428749204,0.19432848633965574,-0.10718036336826706,0.35250503124233246,-0.1637002148171849,0.6070563074848513,-1.084195613202823,-1.084195613202823,-0.3953802206575081,-0.36591524642575174,0.5065492848540103,-1.7897795234170681,-1.2870481640073945,0.32643528456534326,0.32643528456534326,-0.1637002148171849,0.6070563074848513,0.43002989007773285,-0.24951260990209947,0.08646767296946187,0.16754792955183684,0.9459521537888521 | 3,477 |
Cholesterol biosynthesis | 10 | 20 | 2.98653 | 0.002822 | Q14739,Q15125,O76062,Q9UBM7,P04035,Q14534,Q15392,Q15800,P48449,Q16850 | Processes and pathways | Reactome Pathways | msigdb_reactome | 224,100,69,205,235,300,170,314,55,95 | 519,69,878,235,1510,326,55,1656,2737,3330,300,224,100,3222,170,1465,314,95,1872,205 | 0.6813299364803377,2.5631141361485468,0.35250503124233246,1.2664947720455977,0.03178702145824545,0.992819324362481,2.8261975000437003,-0.023406543396603797,-0.5449670887544821,-1.3562641561568651,1.0624319661056087,1.3329848954478216,2.250265534513931,-1.0510617648762144,1.6337937661071684,0.05919085303596074,1.0393185235252296,2.30667735249979,-0.10718036336826706,1.4204955543112385 | 3,477 |
Anion transmembrane transport | 19 | 46 | 2.977539 | 0.002906 | P51790,Q14728,Q9UBX3,P51798,Q13546,Q9Y619,P45880,P55011,P21796,Q9UHG3,P30825,Q96NB2,Q8TB61,P41440,O75746,O75915,Q4KMQ2,P08183,Q9UJS0 | Processes and pathways | GO Biological process | msigdb_gobp | 132,260,398,135,391,550,29,652,33,34,298,449,320,199,454,587,479,112,250 | 2441,2808,770,454,587,2088,1317,1086,1509,112,1439,880,1038,33,298,1515,199,29,132,135,2398,776,652,1325,1718,391,260,3374,1400,479,2870,320,449,3196,2922,699,1690,1813,2259,398,34,250,982,872,2996,550 | -0.3953802206575081,-0.6058872085760314,0.43002989007773285,0.7546817132763226,0.5820894631601891,-0.22076897182307467,0.11361867633969869,0.22098784106991715,0.03178702145824545,2.01913202361103,0.05919085303596074,0.35250503124233246,0.24752710744962664,3.42971985718421,1.0624319661056087,0.03178702145824545,1.4421732031013788,3.5373871392999625,1.8599120159105682,1.8397070212293376,-0.36591524642575174,0.43002989007773285,0.5318368798696025,0.11361867633969869,-0.05119875428749204,0.8510897924183402,1.1766660588890563,-1.5329887599381864,0.08646767296946187,0.7303321085557116,-0.6365864594340644,1.0161145516991787,0.7789314573393142,-0.9853526277263864,-0.6674474549492035,0.5065492848540103,-0.023406543396603797,-0.0791229327418185,-0.2783976197724557,0.8510897924183402,3.42971985718421,1.2217504607212524,0.3002497533746457,0.37846003298308656,-0.7296617004136831,0.6566756516668444 | 3,477 |
Sphingolipid metabolism | 6 | 13 | 2.97428 | 0.002937 | P16278,O95470,Q06136,Q13510,P04062,Q16739 | Processes and pathways | KEGG Pathways | msigdb_kegg | 40,139,44,26,125,191 | 400,1137,1432,2086,139,125,212,2560,40,44,26,191,1748 | 0.8271346805755291,0.19432848633965574,0.05919085303596074,-0.22076897182307467,1.8194332531953932,1.8800487114656554,1.3549837745822957,-0.45475787720939426,3.143677150224885,3.078220375517014,3.658124352450116,1.4852926279143495,-0.05119875428749204 | 3,477 |
Calcium-binding protein | 9 | 19 | 2.967245 | 0.003005 | Q14257,Q9BRK5,O43852,Q02818,P41208,Q15293,P80303,P0DP25,P43307 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 164,264,234,83,118,151,25,122,93 | 234,122,2450,3371,118,93,3123,25,83,164,151,3099,927,268,1676,901,1807,264,1029 | 1.2664947720455977,1.9201190775732102,-0.3953802206575081,-1.5329887599381864,1.9797239596761134,2.325363541577442,-0.8881537960438193,3.658124352450116,2.4362702098241025,1.6755503223412216,1.7581944914524472,-0.8561099941928391,0.32643528456534326,1.1539946679655793,-0.023406543396603797,0.35250503124233246,-0.0791229327418185,1.1766660588890563,0.2739473838070137 | 3,477 |
Oxidative phosphorylation | 28 | 63 | 2.960654 | 0.00307 | P14927,Q9UDW1,O14548,P14406,P56385,O95169,O75964,P22695,P48047,P13073,Q15904,O75947,O43676,Q9Y5K8,O95168,Q93050,O14949,P00846,Q9Y487,O95299,O96000,O43674,P24539,P36543,Q16795,P03886,P21281,P06576 | Processes and pathways | KEGG Pathways | msigdb_kegg | 140,142,642,24,405,42,43,554,555,297,442,433,68,471,561,72,452,87,359,714,716,222,591,349,756,619,623,495 | 1369,642,452,222,68,3409,911,1832,843,2847,2026,1251,433,43,561,42,2664,714,716,1142,87,619,2556,495,1639,2209,297,24,2285,140,1642,2212,845,623,2093,1041,554,591,1647,2902,2160,2624,957,349,1707,555,2570,2297,753,405,2628,3154,442,3020,756,3254,72,2800,142,1752,359,471,946 | 0.08646767296946187,0.5318368798696025,0.7546817132763226,1.3329848954478216,2.598866826737196,-1.7523935642470363,0.32643528456534326,-0.10718036336826706,0.37846003298308656,-0.6365864594340644,-0.19216530124130277,0.14064504133157937,0.7789314573393142,3.078220375517014,0.6070563074848513,3.094651561884198,-0.5147428618246798,0.48115289640719744,0.48115289640719744,0.19432848633965574,2.3995294646169643,0.557016627936463,-0.45475787720939426,0.7058818007064585,-0.023406543396603797,-0.2783976197724557,1.0624319661056087,3.732375271475552,-0.30742542710923365,1.8194332531953932,-0.023406543396603797,-0.2783976197724557,0.37846003298308656,0.557016627936463,-0.22076897182307467,0.24752710744962664,0.6319180709039718,0.5820894631601891,-0.023406543396603797,-0.6674474549492035,-0.24951260990209947,-0.48467366246800686,0.3002497533746457,0.9459521537888521,-0.05119875428749204,0.6319180709039718,-0.45475787720939426,-0.30742542710923365,0.45564675544928607,0.8271346805755291,-0.48467366246800686,-0.9203741657960346,0.7789314573393142,-0.7610185329208947,0.45564675544928607,-1.1175185363069542,2.5631141361485468,-0.575347982490337,1.8194332531953932,-0.05119875428749204,0.9459521537888521,0.7546817132763226,0.32643528456534326 | 3,477 |
Glycosphingolipid metabolism | 7 | 16 | 2.950082 | 0.003177 | P06865,P16278,P10619,Q13510,P07602,P04062,Q16739 | Processes and pathways | Reactome Pathways | msigdb_reactome | 198,40,179,26,60,125,191 | 835,2086,125,212,198,60,1572,179,2560,40,369,26,191,2648,1748,581 | 0.37846003298308656,-0.22076897182307467,1.8800487114656554,1.3549837745822957,1.4421732031013788,2.757163757995302,0.004254965933470663,1.5706040688271496,-0.45475787720939426,3.143677150224885,0.8987110224111641,3.658124352450116,1.4852926279143495,-0.48467366246800686,-0.05119875428749204,0.6070563074848513 | 3,477 |
Sterol biosynthetic process | 11 | 27 | 2.938603 | 0.003297 | Q14739,Q15125,O76062,Q9UBM7,P04035,Q14534,Q15392,Q15800,O76054,P48449,Q16850 | Processes and pathways | GO Biological process | msigdb_gobp | 224,100,69,205,235,300,170,314,86,55,95 | 771,519,86,69,913,2030,235,2970,1510,1087,326,1971,55,2908,1656,2737,3330,300,224,100,3222,170,1465,314,95,205,870 | 0.43002989007773285,0.6813299364803377,2.3995294646169643,2.5631141361485468,0.32643528456534326,-0.19216530124130277,1.2664947720455977,-0.7296617004136831,0.03178702145824545,0.22098784106991715,0.992819324362481,-0.1637002148171849,2.8261975000437003,-0.6674474549492035,-0.023406543396603797,-0.5449670887544821,-1.3562641561568651,1.0624319661056087,1.3329848954478216,2.250265534513931,-1.0510617648762144,1.6337937661071684,0.05919085303596074,1.0393185235252296,2.30667735249979,1.4204955543112385,0.37846003298308656 | 3,477 |
Abnormal circulating lipid concentration | 28 | 82 | 2.930235 | 0.003387 | P16219,P22830,O95470,Q92734,O75845,O43772,Q15056,P11310,P56589,Q15392,Q15904,Q15800,Q9NZJ7,P23786,P07602,P40855,P38571,Q9UBM7,P37268,Q8N511,P06280,O75381,Q14739,Q15125,P28070,O75880,Q9UJS0,O75844 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 498,499,139,269,519,22,409,280,163,170,442,314,581,310,60,319,189,205,326,79,212,585,224,100,348,473,250,123 | 2080,1565,842,22,585,987,123,519,473,139,2089,952,212,1768,60,1254,280,498,499,310,348,1910,1380,750,2506,2675,2288,326,189,319,1708,2218,2939,2048,3172,808,594,3247,2098,2733,3045,163,995,722,1524,3151,3261,654,3421,1977,1978,2582,2688,224,409,100,170,1465,314,442,853,1102,2178,1794,79,761,269,1682,2596,2131,1493,2008,739,581,205,1753,250,1888,3323,1366,944,3324 | -0.22076897182307467,0.004254965933470663,0.37846003298308656,3.834814628505806,0.5820894631601891,0.2739473838070137,1.900117577201474,0.6813299364803377,0.7303321085557116,1.8194332531953932,-0.22076897182307467,0.3002497533746457,1.3549837745822957,-0.0791229327418185,2.757163757995302,0.14064504133157937,1.1083901252715689,0.7058818007064585,0.7058818007064585,1.0393185235252296,0.9459521537888521,-0.135372349749194,0.08646767296946187,0.45564675544928607,-0.42499391779294676,-0.5147428618246798,-0.30742542710923365,0.992819324362481,1.4852926279143495,1.0161145516991787,-0.05119875428749204,-0.2783976197724557,-0.6984719430678344,-0.19216530124130277,-0.9527730995631476,0.4043013153370249,0.5820894631601891,-1.1175185363069542,-0.22076897182307467,-0.5449670887544821,-0.7925442764842194,1.6755503223412216,0.2739473838070137,0.48115289640719744,0.03178702145824545,-0.9203741657960346,-1.151032748253348,0.5318368798696025,-1.8652808653557933,-0.1637002148171849,-0.1637002148171849,-0.45475787720939426,-0.5147428618246798,1.3329848954478216,0.8271346805755291,2.250265534513931,1.6337937661071684,0.05919085303596074,1.0393185235252296,0.7789314573393142,0.37846003298308656,0.22098784106991715,-0.24951260990209947,-0.0791229327418185,2.4909615357157167,0.45564675544928607,1.1539946679655793,-0.023406543396603797,-0.45475787720939426,-0.22076897182307467,0.05919085303596074,-0.1637002148171849,0.48115289640719744,0.6070563074848513,1.4204955543112385,-0.05119875428749204,1.2217504607212524,-0.10718036336826706,-1.3215534429867286,0.11361867633969869,0.32643528456534326,-1.3215534429867286 | 3,477 |
Sphingolipid biosynthetic process | 9 | 20 | 2.92369 | 0.003459 | O15121,Q99805,O95470,Q06136,P27544,Q13510,Q96G23,P04062,Q16739 | Processes and pathways | GO Biological process | msigdb_gobp | 400,129,139,44,78,26,155,125,191 | 400,1137,1432,139,125,1839,2562,78,811,44,26,191,2116,3402,155,129,429,1748,768,2379 | 0.8271346805755291,0.19432848633965574,0.05919085303596074,1.8194332531953932,1.8800487114656554,-0.10718036336826706,-0.45475787720939426,2.4909615357157167,0.4043013153370249,3.078220375517014,3.658124352450116,1.4852926279143495,-0.22076897182307467,-1.6783352899588402,1.7170158615945028,1.8800487114656554,0.8030821726200548,-0.05119875428749204,0.45564675544928607,-0.3365974794064053 | 3,477 |
Peptide binding | 21 | 71 | 2.907649 | 0.003642 | P10321,Q8WTV0,Q9BYT8,P24390,O15212,Q14978,Q9BVL2,Q9UIQ6,Q15392,P42892,P04439,P40855,Q9H7Z7,O43731,P52292,Q9NZ08,O14773,P55786,Q99735,Q92973,Q9NQX7 | Functions | GO Molecular function | msigdb_gomf | 497,3,414,27,279,542,425,39,170,53,318,319,201,75,213,92,221,104,375,512,386 | 836,2271,2714,2890,221,279,3267,75,1377,1766,318,2034,2152,2283,497,2284,3005,2094,27,2450,1648,3428,1514,563,1321,2726,319,53,2937,1091,1322,1258,213,1385,1386,104,2050,1658,1209,2346,3250,2631,3094,2915,685,2823,2170,2236,542,1526,170,1732,3,512,2129,2425,636,375,425,414,1232,201,1546,386,3385,92,1421,705,39,2549,2712 | 0.37846003298308656,-0.30742542710923365,-0.5449670887544821,-0.6674474549492035,1.3329848954478216,1.1083901252715689,-1.1847405024855464,2.5271465892925953,0.08646767296946187,-0.0791229327418185,1.0161145516991787,-0.19216530124130277,-0.24951260990209947,-0.30742542710923365,0.7058818007064585,-0.30742542710923365,-0.7610185329208947,-0.22076897182307467,3.6431638120553607,-0.3953802206575081,-0.023406543396603797,-2.058444063533044,0.03178702145824545,0.6070563074848513,0.11361867633969869,-0.5449670887544821,1.0161145516991787,2.8944454237079458,-0.6984719430678344,0.22098784106991715,0.11361867633969869,0.14064504133157937,1.3549837745822957,0.08646767296946187,0.08646767296946187,2.1742112312199944,-0.19216530124130277,-0.023406543396603797,0.16754792955183684,-0.3365974794064053,-1.1175185363069542,-0.48467366246800686,-0.8561099941928391,-0.6674474549492035,0.5065492848540103,-0.6058872085760314,-0.24951260990209947,-0.2783976197724557,0.6566756516668444,0.03178702145824545,1.6337937661071684,-0.05119875428749204,5.112099164366075,0.7058818007064585,-0.22076897182307467,-0.36591524642575174,0.557016627936463,0.8987110224111641,0.8030821726200548,0.8271346805755291,0.16754792955183684,1.4421732031013788,0.03178702145824545,0.8749483092866545,-1.5689864725719174,2.3625615365785997,0.08646767296946187,0.5065492848540103,3.176140028658313,-0.42499391779294676,-0.5147428618246798 | 3,477 |
Endoplasmic reticulum golgi intermediate compartment membrane | 11 | 26 | 2.901515 | 0.003714 | Q9Y3B3,Q08379,Q8N511,Q15904,Q10472,Q9Y282,Q15363,Q9Y3A6,P24390,Q9BVK6,O95070 | Localization | GO Cellular component | msigdb_gocc | 133,390,79,442,525,21,54,490,27,358,434 | 948,2083,1314,434,27,2450,2048,538,993,883,1260,3250,390,525,849,2107,54,442,79,1181,358,2704,1355,21,490,133 | 0.3002497533746457,-0.22076897182307467,0.11361867633969869,0.7789314573393142,3.6431638120553607,-0.3953802206575081,-0.19216530124130277,0.6566756516668444,0.2739473838070137,0.35250503124233246,0.14064504133157937,-1.1175185363069542,0.8510897924183402,0.6813299364803377,0.37846003298308656,-0.22076897182307467,2.8604185472495534,0.7789314573393142,2.4909615357157167,0.19432848633965574,0.9459521537888521,-0.5147428618246798,0.11361867633969869,3.8781904571384658,0.7303321085557116,1.8599120159105682 | 3,477 |
Active transmembrane transporter activity | 31 | 81 | 2.898489 | 0.00375 | P51790,Q9UBX3,P51798,Q9H2J7,Q9UDW1,O00400,O14548,P55011,O95169,P20020,P13073,P98194,Q9HD20,O43676,Q9Y5K8,O95168,P41440,O95202,O95299,O96000,O43674,Q5T3U5,P35670,P36543,P08183,Q9NRK6,P16615,Q15043,P03886,P21281,P06576 | Functions | GO Molecular function | msigdb_gomf | 132,398,135,272,142,387,642,652,42,553,297,313,185,68,471,561,199,324,714,716,222,98,593,349,112,515,621,505,619,623,495 | 387,1369,642,2441,222,68,3409,911,1139,1832,843,2847,2026,1251,561,42,2664,324,714,716,1142,619,2556,1317,1036,1086,495,112,1439,1639,2209,880,1038,297,2285,621,2212,553,845,623,2093,1643,1256,2902,2624,1515,593,349,1707,199,2570,132,135,2297,2398,776,652,2628,313,1325,1718,3250,505,1526,1400,3020,756,98,1281,1009,2922,272,185,515,3256,398,142,1752,872,471,946 | 0.8510897924183402,0.08646767296946187,0.5318368798696025,-0.3953802206575081,1.3329848954478216,2.598866826737196,-1.7523935642470363,0.32643528456534326,0.19432848633965574,-0.10718036336826706,0.37846003298308656,-0.6365864594340644,-0.19216530124130277,0.14064504133157937,0.6070563074848513,3.094651561884198,-0.5147428618246798,0.992819324362481,0.48115289640719744,0.48115289640719744,0.19432848633965574,0.557016627936463,-0.45475787720939426,0.11361867633969869,0.24752710744962664,0.22098784106991715,0.7058818007064585,2.01913202361103,0.05919085303596074,-0.023406543396603797,-0.2783976197724557,0.35250503124233246,0.24752710744962664,1.0624319661056087,-0.30742542710923365,0.557016627936463,-0.2783976197724557,0.6319180709039718,0.37846003298308656,0.557016627936463,-0.22076897182307467,-0.023406543396603797,0.14064504133157937,-0.6674474549492035,-0.48467366246800686,0.03178702145824545,0.5820894631601891,0.9459521537888521,-0.05119875428749204,1.4421732031013788,-0.45475787720939426,1.8599120159105682,1.8397070212293376,-0.30742542710923365,-0.36591524642575174,0.43002989007773285,0.5318368798696025,-0.48467366246800686,1.0393185235252296,0.11361867633969869,-0.05119875428749204,-1.1175185363069542,0.7058818007064585,0.03178702145824545,0.08646767296946187,-0.7610185329208947,0.45564675544928607,2.269128727200785,0.14064504133157937,0.2739473838070137,-0.6674474549492035,1.1539946679655793,1.5281014060315,0.7058818007064585,-1.1175185363069542,0.8510897924183402,1.8194332531953932,-0.05119875428749204,0.37846003298308656,0.7546817132763226,0.32643528456534326 | 3,477 |
Protein targeting | 21 | 121 | 2.88958 | 0.003858 | Q99595,O60830,O60725,Q14108,Q9NS69,O95831,Q9H444,P56589,Q99523,O00165,P46379,Q9Y3D6,O43464,Q15629,P40855,P30536,O14737,Q9UII2,Q8N4H5,P43307,P55786 | Processes and pathways | GO Biological process | msigdb_gobp | 0,1,8,11,19,146,293,163,175,49,50,177,307,58,319,61,316,335,88,93,104 | 984,49,3166,1244,1368,838,2771,316,535,674,307,378,2086,1032,8,1,585,1896,2810,1377,2662,715,1436,520,146,1437,2282,1962,2775,1771,2038,2777,2157,1644,1445,3427,61,2096,1380,956,2778,2726,319,93,50,3296,2048,2457,2396,2681,993,104,163,2101,523,2050,1658,1659,1324,2685,1389,3047,2913,848,1920,3341,11,2112,3374,1526,58,2468,1855,1166,2116,854,1928,1727,858,2120,2358,2918,758,2593,88,2364,1866,577,2877,931,1352,175,1687,0,1013,2995,666,293,531,1745,514,19,3181,3256,1235,2961,1024,1421,3107,335,1950,1552,2607,1132,1364,1556,177,2996,336,1953,615 | 0.2739473838070137,2.961925562747231,-0.9527730995631476,0.14064504133157937,0.08646767296946187,0.37846003298308656,-0.575347982490337,1.0161145516991787,0.6566756516668444,0.5065492848540103,1.0393185235252296,0.8749483092866545,-0.22076897182307467,0.24752710744962664,4.798562508912278,5.715874196634267,0.5820894631601891,-0.135372349749194,-0.6058872085760314,0.08646767296946187,-0.5147428618246798,0.48115289640719744,0.05919085303596074,0.6813299364803377,1.7786774751475314,0.05919085303596074,-0.30742542710923365,-0.1637002148171849,-0.575347982490337,-0.0791229327418185,-0.19216530124130277,-0.575347982490337,-0.24951260990209947,-0.023406543396603797,0.05919085303596074,-2.058444063533044,2.7397803638415104,-0.22076897182307467,0.08646767296946187,0.3002497533746457,-0.575347982490337,-0.5449670887544821,1.0161145516991787,2.325363541577442,2.961925562747231,-1.2527458541591188,-0.19216530124130277,-0.3953802206575081,-0.36591524642575174,-0.5147428618246798,0.2739473838070137,2.1742112312199944,1.6755503223412216,-0.22076897182307467,0.6813299364803377,-0.19216530124130277,-0.023406543396603797,-0.023406543396603797,0.11361867633969869,-0.5147428618246798,0.08646767296946187,-0.7925442764842194,-0.6674474549492035,0.37846003298308656,-0.135372349749194,-1.3911828140592644,4.673528789411234,-0.22076897182307467,-1.5329887599381864,0.03178702145824545,2.7917800083518514,-0.3953802206575081,-0.10718036336826706,0.19432848633965574,-0.22076897182307467,0.37846003298308656,-0.135372349749194,-0.05119875428749204,0.37846003298308656,-0.22076897182307467,-0.3365974794064053,-0.6674474549492035,0.45564675544928607,-0.45475787720939426,2.3995294646169643,-0.3365974794064053,-0.10718036336826706,0.6070563074848513,-0.6365864594340644,0.32643528456534326,0.11361867633969869,1.612805048617125,-0.023406543396603797,5.883876178508293,0.2739473838070137,-0.7296617004136831,0.5318368798696025,1.0854555970140953,0.6813299364803377,-0.05119875428749204,0.7058818007064585,4.0765911800980605,-0.9527730995631476,-1.1175185363069542,0.16754792955183684,-0.6984719430678344,0.2739473838070137,0.08646767296946187,-0.8561099941928391,0.992819324362481,-0.135372349749194,0.03178702145824545,-0.45475787720939426,0.22098784106991715,0.11361867633969869,0.03178702145824545,1.591741995868226,-0.7296617004136831,0.992819324362481,-0.135372349749194,0.5820894631601891 | 3,477 |
Membrane lipid catabolic process | 7 | 12 | 2.889186 | 0.003862 | P50897,P06865,O95470,Q99735,P06280,Q13510,P04062 | Processes and pathways | GO Biological process | msigdb_gobp | 36,198,139,375,212,26,125 | 139,125,717,212,198,1572,369,36,811,26,375,1748 | 1.8194332531953932,1.8800487114656554,0.48115289640719744,1.3549837745822957,1.4421732031013788,0.004254965933470663,0.8987110224111641,3.2565382958940745,0.4043013153370249,3.658124352450116,0.8987110224111641,-0.05119875428749204 | 3,477 |
Phospholipid binding | 10 | 93 | 2.888006 | 0.003877 | P21796,Q8WTV0,P50897,Q14108,P53367,Q9UM22,Q8NCC3,O76054,P07602,P45880 | Functions | GO Molecular function | msigdb_gomf | 33,3,36,11,76,14,17,86,60,29 | 835,1561,2022,838,221,673,674,1893,769,2204,453,1082,3000,950,3168,86,1571,1438,60,3293,3065,2036,3364,2038,1440,620,3037,2337,33,2562,2095,1043,751,29,1778,1654,3338,36,3282,76,780,3049,3341,1978,2170,850,812,11,814,1056,1212,630,2863,1669,1060,2527,2120,2945,2918,383,17,2364,3,2366,1485,2947,865,1806,2648,1543,487,1944,1296,2801,2957,274,581,1236,1305,612,124,2198,14,1238,2548,489,983,1558,2268,2770,1136,2269,945 | 0.37846003298308656,0.004254965933470663,-0.19216530124130277,0.37846003298308656,1.3329848954478216,0.5065492848540103,0.5065492848540103,-0.135372349749194,0.43002989007773285,-0.2783976197724557,0.7546817132763226,0.22098784106991715,-0.7610185329208947,0.3002497533746457,-0.9527730995631476,2.3995294646169643,0.004254965933470663,0.05919085303596074,2.757163757995302,-1.2527458541591188,-0.8242407976278554,-0.19216530124130277,-1.4972122677706563,-0.19216530124130277,0.05919085303596074,0.557016627936463,-0.7925442764842194,-0.3365974794064053,3.42971985718421,-0.45475787720939426,-0.22076897182307467,0.24752710744962664,0.45564675544928607,3.5373871392999625,-0.0791229327418185,-0.023406543396603797,-1.3911828140592644,3.2565382958940745,-1.2186440927684283,2.5271465892925953,0.43002989007773285,-0.7925442764842194,-1.3911828140592644,-0.1637002148171849,-0.24951260990209947,0.37846003298308656,0.4043013153370249,4.673528789411234,0.4043013153370249,0.24752710744962664,0.16754792955183684,0.557016627936463,-0.6365864594340644,-0.023406543396603797,0.24752710744962664,-0.42499391779294676,-0.22076897182307467,-0.6984719430678344,-0.6674474549492035,0.8749483092866545,4.145899257701786,-0.3365974794064053,5.112099164366075,-0.3365974794064053,0.05919085303596074,-0.6984719430678344,0.37846003298308656,-0.0791229327418185,-0.48467366246800686,0.03178702145824545,0.7303321085557116,-0.135372349749194,0.14064504133157937,-0.575347982490337,-0.6984719430678344,1.1539946679655793,0.6070563074848513,0.16754792955183684,0.14064504133157937,0.5820894631601891,1.900117577201474,-0.24951260990209947,4.5844469972857,0.16754792955183684,-0.42499391779294676,0.7303321085557116,0.3002497533746457,0.03178702145824545,-0.2783976197724557,-0.5449670887544821,0.22098784106991715,-0.2783976197724557,0.32643528456534326 | 3,477 |
ATP synthase | 12 | 22 | 2.872347 | 0.004074 | P24539,Q9Y5K8,Q93050,O75964,Q96IX5,P48047,Q15904,P00846,O75947,Q9Y487,P56385,P06576 | Functions | Panther Protein class | panther_protein_class | 591,471,72,43,422,555,442,87,433,359,405,495 | 2847,433,43,87,495,623,2093,591,1647,957,1707,555,753,405,2628,442,1724,72,422,1752,359,471 | -0.6365864594340644,0.7789314573393142,3.078220375517014,2.3995294646169643,0.7058818007064585,0.557016627936463,-0.22076897182307467,0.5820894631601891,-0.023406543396603797,0.3002497533746457,-0.05119875428749204,0.6319180709039718,0.45564675544928607,0.8271346805755291,-0.48467366246800686,0.7789314573393142,-0.05119875428749204,2.5631141361485468,0.8030821726200548,-0.05119875428749204,0.9459521537888521,0.7546817132763226 | 3,477 |
Corneal opacity | 24 | 64 | 2.870944 | 0.004092 | P51648,O75845,Q15056,Q13510,P56589,P16278,Q06136,O96028,P10619,P53701,P40855,Q9UBM7,O95202,P49454,Q86XI2,P06280,O43505,O75381,Q16625,P35670,Q9H9S5,Q9Y5Z9,O75844,P04062 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 500,519,409,26,163,40,44,296,179,181,319,205,324,456,216,212,584,585,225,593,232,111,123,125 | 3463,2080,2081,584,3034,842,1566,2894,585,1698,123,519,2663,324,2089,296,952,125,717,212,1961,2669,179,40,2620,1837,750,2506,593,319,456,500,1452,181,1974,163,1524,3261,1210,44,2860,2349,26,409,2467,2114,225,1468,632,3077,216,1734,1179,2834,1417,232,739,1420,205,1753,941,3140,1366,111 | -3.9465894525816343,-0.22076897182307467,-0.22076897182307467,0.5820894631601891,-0.7925442764842194,0.37846003298308656,0.004254965933470663,-0.6674474549492035,0.5820894631601891,-0.05119875428749204,1.900117577201474,0.6813299364803377,-0.5147428618246798,0.992819324362481,-0.22076897182307467,1.0624319661056087,0.3002497533746457,1.8800487114656554,0.48115289640719744,1.3549837745822957,-0.1637002148171849,-0.5147428618246798,1.5706040688271496,3.143677150224885,-0.48467366246800686,-0.10718036336826706,0.45564675544928607,-0.42499391779294676,0.5820894631601891,1.0161145516991787,0.7546817132763226,0.7058818007064585,0.05919085303596074,1.5493907225373234,-0.1637002148171849,1.6755503223412216,0.03178702145824545,-1.151032748253348,0.16754792955183684,3.078220375517014,-0.6365864594340644,-0.3365974794064053,3.658124352450116,0.8271346805755291,-0.3953802206575081,-0.22076897182307467,1.3329848954478216,0.05919085303596074,0.557016627936463,-0.8242407976278554,1.3549837745822957,-0.05119875428749204,0.19432848633965574,-0.6058872085760314,0.08646767296946187,1.2887410211204224,0.48115289640719744,0.08646767296946187,1.4204955543112385,-0.05119875428749204,0.32643528456534326,-0.8881537960438193,0.11361867633969869,2.0387388219428937 | 3,477 |
Hydrogen ion transport | 12 | 21 | 2.849297 | 0.004382 | P24539,P36543,Q9Y5K8,Q93050,O75964,P48047,Q15904,P00846,P56385,Q9Y487,O75947,P06576 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 591,349,471,72,43,555,442,87,405,359,433,495 | 2847,433,43,87,495,623,2093,591,1647,957,349,1707,555,753,405,2628,442,72,1752,359,471 | -0.6365864594340644,0.7789314573393142,3.078220375517014,2.3995294646169643,0.7058818007064585,0.557016627936463,-0.22076897182307467,0.5820894631601891,-0.023406543396603797,0.3002497533746457,0.9459521537888521,-0.05119875428749204,0.6319180709039718,0.45564675544928607,0.8271346805755291,-0.48467366246800686,0.7789314573393142,2.5631141361485468,-0.05119875428749204,0.9459521537888521,0.7546817132763226 | 3,477 |
Cholesterol metabolism with bloch and kandutschrussell pathways | 10 | 27 | 2.818202 | 0.004829 | Q14739,Q15125,O76062,Q9UBM7,P04035,Q14534,Q15392,Q15800,P48449,Q16850 | Processes and pathways | WikiPathways | msigdb_wp | 224,100,69,205,235,300,170,314,55,95 | 1760,1433,519,69,2029,878,951,235,1510,1447,3271,326,55,2781,1656,2737,3330,300,224,100,3222,170,1465,314,95,1872,205 | -0.0791229327418185,0.05919085303596074,0.6813299364803377,2.5631141361485468,-0.19216530124130277,0.35250503124233246,0.3002497533746457,1.2664947720455977,0.03178702145824545,0.05919085303596074,-1.1847405024855464,0.992819324362481,2.8261975000437003,-0.575347982490337,-0.023406543396603797,-0.5449670887544821,-1.3562641561568651,1.0624319661056087,1.3329848954478216,2.250265534513931,-1.0510617648762144,1.6337937661071684,0.05919085303596074,1.0393185235252296,2.30667735249979,-0.10718036336826706,1.4204955543112385 | 3,477 |
Steroid biosynthesis | 9 | 13 | 2.817333 | 0.004842 | P38571,Q15125,O76062,Q9UBM7,Q15392,Q14534,Q15800,P48449,Q16850 | Processes and pathways | KEGG Pathways | msigdb_kegg | 189,100,69,205,170,300,314,55,95 | 519,69,3271,326,189,55,300,100,170,1465,314,95,205 | 0.6813299364803377,2.5631141361485468,-1.1847405024855464,0.992819324362481,1.4852926279143495,2.8261975000437003,1.0624319661056087,2.250265534513931,1.6337937661071684,0.05919085303596074,1.0393185235252296,2.30667735249979,1.4204955543112385 | 3,477 |
Abnormal retinal artery morphology | 10 | 22 | 2.80479 | 0.005035 | P06865,P16278,P10619,P00846,Q9NZJ7,Q15056,P03886,Q13510,P07602,P17900 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 198,40,179,87,581,409,619,26,60,369 | 949,842,87,619,2556,198,60,1572,179,2671,40,369,646,2506,2573,1524,26,409,1735,581,1753,1366 | 0.3002497533746457,0.37846003298308656,2.3995294646169643,0.557016627936463,-0.45475787720939426,1.4421732031013788,2.757163757995302,0.004254965933470663,1.5706040688271496,-0.5147428618246798,3.143677150224885,0.8987110224111641,0.5318368798696025,-0.42499391779294676,-0.45475787720939426,0.03178702145824545,3.658124352450116,0.8271346805755291,-0.05119875428749204,0.6070563074848513,-0.05119875428749204,0.11361867633969869 | 3,477 |
calmodulin-related | 8 | 13 | 2.783099 | 0.005384 | Q14257,Q9BRK5,O43852,Q02818,P41208,Q15293,P80303,P0DP25 | Functions | Panther Protein class | panther_protein_class | 164,264,234,83,118,151,25,122 | 234,122,2453,3371,118,25,83,164,151,268,901,1807,264 | 1.2664947720455977,1.9201190775732102,-0.3953802206575081,-1.5329887599381864,1.9797239596761134,3.658124352450116,2.4362702098241025,1.6755503223412216,1.7581944914524472,1.1539946679655793,0.35250503124233246,-0.0791229327418185,1.1766660588890563 | 3,477 |
serine protease | 8 | 17 | 2.77372 | 0.005542 | Q8N2K0,P42785,Q9H3G5,Q9HB40,Q16740,P10619,P67812,O14773 | Functions | Panther Protein class | panther_protein_class | 261,7,15,16,113,179,312,221 | 221,307,179,3245,3116,2451,1651,7,3071,312,113,1530,2473,261,3177,15,16 | 1.3329848954478216,1.0393185235252296,1.5706040688271496,-1.1175185363069542,-0.8881537960438193,-0.3953802206575081,-0.023406543396603797,4.93319079393823,-0.8242407976278554,1.0393185235252296,2.01913202361103,0.03178702145824545,-0.3953802206575081,1.1766660588890563,-0.9527730995631476,4.362495893754808,4.173401607815876 | 3,477 |
Outer membrane | 24 | 89 | 2.770138 | 0.005603 | Q6UXV4,Q86UT6,Q99720,Q9NS69,Q99623,P45880,P21796,O00165,Q9Y3D6,O43169,P09601,Q96RL7,P30536,Q99536,Q9Y512,Q9UBM7,Q5XKP0,Q8WY22,O60313,Q16891,Q8N4H5,Q13505,Q9NQG6,Q9NX63 | Localization | GO Cellular component | msigdb_gocc | 527,394,12,19,413,29,33,49,177,51,52,577,61,333,336,205,464,203,453,463,88,236,514,257 | 49,836,985,3464,51,453,1433,987,1377,2662,2029,1437,2030,3184,2153,52,3004,33,61,1447,2394,1154,1846,29,808,594,1520,3045,3406,1457,684,2230,236,2584,1720,1526,2468,463,2116,1597,464,784,527,2179,394,785,2124,2243,894,820,88,1110,2420,2316,761,203,2247,929,577,1121,333,413,12,1870,2954,1808,1543,1294,3375,825,3104,514,935,19,3445,1747,2264,1303,257,1748,581,1023,205,980,982,1556,177,336,1429 | 2.961925562747231,0.37846003298308656,0.2739473838070137,-4.056663271202593,2.8944454237079458,0.7546817132763226,0.05919085303596074,0.2739473838070137,0.08646767296946187,-0.5147428618246798,-0.19216530124130277,0.05919085303596074,-0.19216530124130277,-0.9853526277263864,-0.24951260990209947,2.8944454237079458,-0.7610185329208947,3.42971985718421,2.7397803638415104,0.05919085303596074,-0.36591524642575174,0.19432848633965574,-0.10718036336826706,3.5373871392999625,0.4043013153370249,0.5820894631601891,0.03178702145824545,-0.7925442764842194,-1.7152465177215432,0.05919085303596074,0.5065492848540103,-0.2783976197724557,1.2664947720455977,-0.45475787720939426,-0.05119875428749204,0.03178702145824545,-0.3953802206575081,0.7546817132763226,-0.22076897182307467,0.004254965933470663,0.7546817132763226,0.43002989007773285,0.6813299364803377,-0.24951260990209947,0.8510897924183402,0.43002989007773285,-0.22076897182307467,-0.2783976197724557,0.35250503124233246,0.4043013153370249,2.3995294646169643,0.22098784106991715,-0.36591524642575174,-0.30742542710923365,0.45564675544928607,1.4204955543112385,-0.2783976197724557,0.32643528456534326,0.6070563074848513,0.22098784106991715,0.992819324362481,0.8271346805755291,4.673528789411234,-0.10718036336826706,-0.6984719430678344,-0.0791229327418185,0.03178702145824545,0.14064504133157937,-1.5329887599381864,0.4043013153370249,-0.8561099941928391,0.7058818007064585,0.32643528456534326,4.0765911800980605,-2.5930433003520634,-0.05119875428749204,-0.2783976197724557,0.14064504133157937,1.1992511003937982,-0.05119875428749204,0.6070563074848513,0.2739473838070137,1.4204955543112385,0.3002497533746457,0.3002497533746457,0.03178702145824545,1.591741995868226,0.992819324362481,0.08646767296946187 | 3,477 |
Cristae formation | 12 | 21 | 2.768643 | 0.005629 | Q6UXV4,Q9Y512,O75964,Q5XKP0,P48047,Q16891,Q13505,P00846,P56385,O75947,Q9NX63,P06576 | Processes and pathways | Reactome Pathways | msigdb_reactome | 527,336,43,464,555,463,236,87,405,433,257,495 | 987,433,43,87,495,1319,591,1647,957,2394,555,753,405,236,463,464,527,2954,2264,257,336 | 0.2739473838070137,0.7789314573393142,3.078220375517014,2.3995294646169643,0.7058818007064585,0.11361867633969869,0.5820894631601891,-0.023406543396603797,0.3002497533746457,-0.36591524642575174,0.6319180709039718,0.45564675544928607,0.8271346805755291,1.2664947720455977,0.7546817132763226,0.7546817132763226,0.6813299364803377,-0.6984719430678344,-0.2783976197724557,1.1992511003937982,0.992819324362481 | 3,477 |
Alcohol metabolic process | 21 | 89 | 2.755536 | 0.00586 | Q8WTV0,Q13510,Q9BY49,Q15392,Q14534,Q9NZC3,Q15800,P48449,O76062,Q9UBM7,O94788,O15118,O76054,P00374,P30837,Q16850,Q14739,Q15125,P05067,P04035,P04062 | Processes and pathways | GO Biological process | msigdb_gobp | 3,26,156,170,300,180,314,55,69,205,77,85,86,90,91,95,224,100,102,235,125 | 3143,85,1137,1432,3217,2661,1830,771,519,876,86,69,77,913,3086,90,2030,235,125,102,1508,2970,3067,1510,3294,3351,1087,2619,3088,2216,91,750,680,3271,326,1971,1776,55,564,3172,2512,1781,3247,1384,500,2908,1656,3451,2575,722,2104,2914,2737,3261,848,26,3389,1787,3330,300,224,1985,1212,100,3222,170,1465,314,1100,95,2864,784,2528,1994,3,2596,1413,3241,2878,694,450,156,466,2924,1128,180,205,1130,2611 | -0.9203741657960346,2.3995294646169643,0.19432848633965574,0.05919085303596074,-1.0510617648762144,-0.5147428618246798,-0.10718036336826706,0.43002989007773285,0.6813299364803377,0.35250503124233246,2.3995294646169643,2.5631141361485468,2.4909615357157167,0.32643528456534326,-0.8561099941928391,2.3625615365785997,-0.19216530124130277,1.2664947720455977,1.8800487114656554,2.2313425780094427,0.03178702145824545,-0.7296617004136831,-0.8242407976278554,0.03178702145824545,-1.2527458541591188,-1.4263119738467533,0.22098784106991715,-0.48467366246800686,-0.8561099941928391,-0.2783976197724557,2.3625615365785997,0.45564675544928607,0.5065492848540103,-1.1847405024855464,0.992819324362481,-0.1637002148171849,-0.0791229327418185,2.8261975000437003,0.6070563074848513,-0.9527730995631476,-0.42499391779294676,-0.0791229327418185,-1.1175185363069542,0.08646767296946187,0.7058818007064585,-0.6674474549492035,-0.023406543396603797,-2.7679958875852217,-0.45475787720939426,0.48115289640719744,-0.22076897182307467,-0.6674474549492035,-0.5449670887544821,-1.151032748253348,0.37846003298308656,3.658124352450116,-1.6052082141099608,-0.0791229327418185,-1.3562641561568651,1.0624319661056087,1.3329848954478216,-0.1637002148171849,0.16754792955183684,2.250265534513931,-1.0510617648762144,1.6337937661071684,0.05919085303596074,1.0393185235252296,0.22098784106991715,2.30667735249979,-0.6365864594340644,0.43002989007773285,-0.42499391779294676,-0.1637002148171849,5.112099164366075,-0.45475787720939426,0.08646767296946187,-1.084195613202823,-0.6365864594340644,0.5065492848540103,0.7789314573393142,1.7170158615945028,0.7546817132763226,-0.6674474549492035,0.22098784106991715,1.5706040688271496,1.4204955543112385,0.22098784106991715,-0.45475787720939426 | 3,477 |
Transmembrane transport | 78 | 228 | 2.739885 | 0.006146 | Q99595,O60830,Q8WTV0,Q9P246,Q9NS69,O43772,Q9Y619,Q9BSK2,Q13423,P45880,O14925,P21796,P49755,Q9UHG3,Q8IXU6,O75964,P48047,P20020,Q9C0H2,Q15629,P07947,Q9UJZ1,P00846,O75381,O75915,Q5T3U5,P24539,P35670,P50416,P05067,Q6NUK1,P08183,P16615,P0DP25,O75844,Q9UKG1,P04062,Q9H2V7,P51790,Q8NEW0,P51798,Q9UDW1,O95831,Q99523,Q9HD20,P41440,P78417,Q16625,Q70HW3,Q9UJS0,Q14728,Q9H2J7,Q8IYU8,Q8N4V1,P30825,P13073,P98194,P23786,Q8TB61,P11166,O95202,P36543,P38435,O43615,Q9UBX3,Q13546,O00400,Q99623,Q6P4A7,P56385,Q96NB2,O75947,O75746,Q9BZF1,Q4KMQ2,Q9NRK6,Q15043,P06576 | Processes and pathways | GO Biological process | msigdb_gobp | 0,1,3,533,19,22,550,548,28,29,535,33,538,34,38,43,555,553,48,58,562,612,87,585,587,98,591,593,594,102,632,112,621,122,123,124,125,130,132,137,135,142,146,175,185,199,214,225,242,250,260,272,268,284,298,297,313,310,320,325,324,349,361,378,398,391,387,413,410,405,449,433,454,487,479,515,505,495 | 3216,2806,1244,3335,387,1369,642,2613,535,2441,378,1565,22,2808,3268,1503,1,770,1139,2893,1832,1250,2847,585,1896,454,123,587,433,43,1377,324,2088,146,1437,1142,87,2556,125,1317,1036,102,1086,1509,1901,495,1438,1770,562,1379,3065,112,1439,1639,1903,122,2209,1771,325,2970,880,1038,297,2285,621,2211,1907,553,845,623,2093,2851,33,1643,310,591,1647,3427,1648,1256,3428,2453,298,1043,1380,2624,1447,1515,593,3280,957,349,361,1707,3336,199,2218,29,3296,992,555,538,2396,594,1779,132,135,1520,2398,776,3188,2165,652,753,405,2101,2050,2628,1658,1324,2910,214,313,1325,2913,3152,1718,3250,810,3013,886,1457,684,962,1920,28,391,2406,2519,2688,260,922,3374,505,2351,1526,58,1400,2175,225,2523,1166,479,98,632,1061,410,3078,1670,1928,242,2918,2870,2361,38,268,2990,284,2831,1534,1281,137,320,2421,3,2365,1410,1009,2949,449,1685,931,3241,175,0,413,1013,1540,735,1807,3196,548,1808,2922,2704,487,48,737,699,272,130,1015,1690,1745,1813,185,2259,515,19,533,398,142,1024,3107,34,1752,250,612,124,1237,982,872,1029,2996,873,834,550,3084 | 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| 3,477 |
Establishment of protein localization to membrane | 19 | 93 | 2.73585 | 0.006222 | O60725,Q9NS69,Q8N4V1,Q9H444,P56589,Q9Y3D6,P46379,P98194,Q15070,Q9HD20,Q15629,P40855,O14737,Q9Y512,Q96A33,O15118,P43307,Q13439,P0DP25 | Processes and pathways | GO Biological process | msigdb_gobp | 8,19,284,293,163,177,50,313,182,185,58,319,316,336,342,85,93,352,122 | 984,1368,838,316,2554,85,1079,2086,1032,8,2895,2810,1377,2029,2282,1962,2775,122,1644,2287,2096,1380,2778,2726,319,1577,93,50,2161,2457,2681,1387,163,2101,2735,2050,1657,1658,3435,313,2913,780,1457,1920,3341,352,1269,2636,371,3374,182,58,442,1530,2116,1469,1727,2918,758,284,1533,2244,2316,2364,2365,342,1999,931,2190,293,1296,3057,531,185,2259,514,19,3181,704,3256,1024,1421,3107,1950,1305,1552,1132,1362,1823,177,2996,336,1953 | 0.2739473838070137,0.08646767296946187,0.37846003298308656,1.0161145516991787,-0.45475787720939426,2.3995294646169643,0.22098784106991715,-0.22076897182307467,0.24752710744962664,4.798562508912278,-0.6674474549492035,-0.6058872085760314,0.08646767296946187,-0.19216530124130277,-0.30742542710923365,-0.1637002148171849,-0.575347982490337,1.9201190775732102,-0.023406543396603797,-0.30742542710923365,-0.22076897182307467,0.08646767296946187,-0.575347982490337,-0.5449670887544821,1.0161145516991787,0.004254965933470663,2.325363541577442,2.961925562747231,-0.24951260990209947,-0.3953802206575081,-0.5147428618246798,0.08646767296946187,1.6755503223412216,-0.22076897182307467,-0.5449670887544821,-0.19216530124130277,-0.023406543396603797,-0.023406543396603797,-2.2582618800655756,1.0393185235252296,-0.6674474549492035,0.43002989007773285,0.05919085303596074,-0.135372349749194,-1.3911828140592644,0.9459521537888521,0.14064504133157937,-0.48467366246800686,0.8987110224111641,-1.5329887599381864,1.5493907225373234,2.7917800083518514,0.7789314573393142,0.03178702145824545,-0.22076897182307467,0.05919085303596074,-0.05119875428749204,-0.6674474549492035,0.45564675544928607,1.1083901252715689,0.03178702145824545,-0.2783976197724557,-0.30742542710923365,-0.3365974794064053,-0.3365974794064053,0.9694321064173009,-0.1637002148171849,0.32643528456534326,-0.24951260990209947,1.0854555970140953,0.14064504133157937,-0.7925442764842194,0.6813299364803377,1.5281014060315,-0.2783976197724557,0.7058818007064585,4.0765911800980605,-0.9527730995631476,0.5065492848540103,-1.1175185363069542,0.2739473838070137,0.08646767296946187,-0.8561099941928391,-0.135372349749194,0.14064504133157937,0.03178702145824545,0.22098784106991715,0.11361867633969869,-0.0791229327418185,1.591741995868226,-0.7296617004136831,0.992819324362481,-0.135372349749194 | 3,477 |
Translocation | 8 | 46 | 2.727128 | 0.006389 | Q99595,O60830,O43615,Q9BVL2,Q9NS69,Q9BTX1,P41208,Q15629 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 0,1,378,425,19,218,118,58 | 984,535,841,378,1829,1,585,2896,806,1321,751,118,1322,1258,1386,995,2101,1658,3406,3379,2229,58,1166,2176,858,689,2873,445,1005,1936,1407,1283,1114,662,931,1290,0,218,425,2067,1876,19,1497,1751,1072,1953 | 0.2739473838070137,0.6566756516668444,0.37846003298308656,0.8749483092866545,-0.10718036336826706,5.715874196634267,0.5820894631601891,-0.6674474549492035,0.4043013153370249,0.11361867633969869,0.45564675544928607,1.9797239596761134,0.11361867633969869,0.14064504133157937,0.08646767296946187,0.2739473838070137,-0.22076897182307467,-0.023406543396603797,-1.7152465177215432,-1.5689864725719174,-0.2783976197724557,2.7917800083518514,0.19432848633965574,-0.24951260990209947,0.37846003298308656,0.5065492848540103,-0.6365864594340644,0.7789314573393142,0.2739473838070137,-0.135372349749194,0.08646767296946187,0.14064504133157937,0.22098784106991715,0.5318368798696025,0.32643528456534326,0.14064504133157937,5.883876178508293,1.3549837745822957,0.8030821726200548,-0.19216530124130277,-0.10718036336826706,4.0765911800980605,0.05919085303596074,-0.05119875428749204,0.24752710744962664,-0.135372349749194 | 3,477 |
Oxidoreductase activity acting on the ch ch group of donors | 10 | 27 | 2.718628 | 0.006555 | Q14739,Q9NZ01,Q8N4Q0,O76062,Q9H7Z7,Q9UBM7,Q15392,Q15067,P11310,Q9BY49 | Functions | GO Molecular function | msigdb_gomf | 224,294,4,69,201,205,170,237,280,156 | 306,69,2721,280,498,1041,2158,2160,1152,2781,3172,3237,2732,224,3095,237,170,784,1170,4,482,1865,156,201,1493,294,205 | 1.0393185235252296,2.5631141361485468,-0.5449670887544821,1.1083901252715689,0.7058818007064585,0.24752710744962664,-0.24951260990209947,-0.24951260990209947,0.19432848633965574,-0.575347982490337,-0.9527730995631476,-1.084195613202823,-0.5449670887544821,1.3329848954478216,-0.8561099941928391,1.2664947720455977,1.6337937661071684,0.43002989007773285,0.19432848633965574,5.100334225775537,0.7303321085557116,-0.10718036336826706,1.7170158615945028,1.4421732031013788,0.05919085303596074,1.0854555970140953,1.4204955543112385 | 3,477 |
Calcium ion binding | 32 | 88 | 2.714877 | 0.00663 | Q9UBC2,Q9P246,Q9BRK5,Q9UM22,Q8IYU8,Q15293,P80303,P67936,O95302,Q14257,Q96D71,O14795,Q96AY3,Q9Y680,Q8WVQ1,O95202,P55327,O75746,Q02818,Q96A33,Q14574,Q13813,Q6NUK1,O43852,Q9UJS0,Q9NWM8,P41208,P16615,Q14651,P0DP25,P12429,Q04721 | Functions | GO Molecular function | msigdb_gomf | 534,533,264,14,268,151,25,406,31,164,692,673,574,63,465,324,209,454,83,342,599,478,632,234,250,639,118,621,503,122,620,381 | 835,673,1311,2086,1565,234,1434,2774,454,877,324,31,1571,1438,1770,3065,3364,122,620,1146,3003,3115,953,679,2560,621,1965,718,1907,3037,2449,2450,1574,3090,2453,3371,118,3091,1776,1654,3282,209,3123,1523,406,25,1049,83,1210,381,3094,1162,887,2519,478,1332,164,599,503,151,2355,632,2918,2243,894,268,1482,465,342,574,901,692,1807,264,2648,1186,2835,639,2378,533,534,2545,3107,250,14,1362,2268,63 | 0.37846003298308656,0.5065492848540103,0.11361867633969869,-0.22076897182307467,0.004254965933470663,1.2664947720455977,0.05919085303596074,-0.575347982490337,0.7546817132763226,0.35250503124233246,0.992819324362481,3.4914795286943017,0.004254965933470663,0.05919085303596074,-0.0791229327418185,-0.8242407976278554,-1.4972122677706563,1.9201190775732102,0.557016627936463,0.19432848633965574,-0.7610185329208947,-0.8881537960438193,0.3002497533746457,0.5065492848540103,-0.45475787720939426,0.557016627936463,-0.1637002148171849,0.48115289640719744,-0.135372349749194,-0.7925442764842194,-0.3953802206575081,-0.3953802206575081,0.004254965933470663,-0.8561099941928391,-0.3953802206575081,-1.5329887599381864,1.9797239596761134,-0.8561099941928391,-0.0791229327418185,-0.023406543396603797,-1.2186440927684283,1.3769014390666614,-0.8881537960438193,0.03178702145824545,0.8271346805755291,3.658124352450116,0.24752710744962664,2.4362702098241025,0.16754792955183684,0.8749483092866545,-0.8561099941928391,0.19432848633965574,0.35250503124233246,-0.42499391779294676,0.7303321085557116,0.11361867633969869,1.6755503223412216,0.5820894631601891,0.7058818007064585,1.7581944914524472,-0.3365974794064053,0.557016627936463,-0.6674474549492035,-0.2783976197724557,0.35250503124233246,1.1539946679655793,0.05919085303596074,0.7546817132763226,0.9694321064173009,0.6070563074848513,0.35250503124233246,0.5065492848540103,-0.0791229327418185,1.1766660588890563,-0.48467366246800686,0.19432848633965574,-0.6058872085760314,0.557016627936463,-0.3365974794064053,0.6813299364803377,0.6813299364803377,-0.42499391779294676,-0.8561099941928391,1.2217504607212524,4.5844469972857,0.11361867633969869,-0.2783976197724557,2.7397803638415104 | 3,477 |
Oxidoreductase | 28 | 120 | 2.71022 | 0.006724 | Q8N4Q0,P14927,Q9UDW1,Q96CU9,O95831,P14406,P11310,Q9BY49,Q13423,Q9NZ01,O95169,Q9BV57,P49419,Q15392,Q14534,O43169,Q15800,O76062,Q9H7Z7,Q9UBM7,O94788,P00374,P30837,O43674,Q16850,Q8N0U8,Q14739,Q15067 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 4,140,142,149,146,24,280,156,28,294,42,303,45,170,300,51,314,69,201,205,77,90,91,222,95,96,224,237 | 1759,1369,642,306,948,51,2492,3217,222,3409,1374,2661,1832,843,2026,519,473,3183,69,77,561,42,146,2281,2812,1637,90,2332,1142,619,2556,1702,3357,1508,3306,1254,2209,280,2970,3067,3234,2040,24,3294,140,3351,1642,845,1041,2722,3039,2158,2902,3090,3007,2452,91,2160,1446,2505,2392,1152,2454,3425,3043,1776,3072,45,3172,2512,1781,1973,2297,3316,2732,1974,2914,847,1717,1267,28,300,224,3095,237,170,314,852,3020,756,95,2790,1337,1926,1170,2416,96,2990,4,482,1341,2991,1994,149,2949,2427,303,156,201,1493,1188,466,1420,294,3256,205,2927,142,1365,946 | -0.0791229327418185,0.08646767296946187,0.5318368798696025,1.0393185235252296,0.3002497533746457,2.8944454237079458,-0.42499391779294676,-1.0510617648762144,1.3329848954478216,-1.7523935642470363,0.08646767296946187,-0.5147428618246798,-0.10718036336826706,0.37846003298308656,-0.19216530124130277,0.6813299364803377,0.7303321085557116,-0.9853526277263864,2.5631141361485468,2.4909615357157167,0.6070563074848513,3.094651561884198,1.7786774751475314,-0.30742542710923365,-0.6058872085760314,-0.023406543396603797,2.3625615365785997,-0.3365974794064053,0.19432848633965574,0.557016627936463,-0.45475787720939426,-0.05119875428749204,-1.461654240448277,0.03178702145824545,-1.2870481640073945,0.14064504133157937,-0.2783976197724557,1.1083901252715689,-0.7296617004136831,-0.8242407976278554,-1.084195613202823,-0.19216530124130277,3.732375271475552,-1.2527458541591188,1.8194332531953932,-1.4263119738467533,-0.023406543396603797,0.37846003298308656,0.24752710744962664,-0.5449670887544821,-0.7925442764842194,-0.24951260990209947,-0.6674474549492035,-0.8561099941928391,-0.7610185329208947,-0.3953802206575081,2.3625615365785997,-0.24951260990209947,0.05919085303596074,-0.42499391779294676,-0.36591524642575174,0.19432848633965574,-0.3953802206575081,-1.9804057079090651,-0.7925442764842194,-0.0791229327418185,-0.8242407976278554,3.061744110987097,-0.9527730995631476,-0.42499391779294676,-0.0791229327418185,-0.1637002148171849,-0.30742542710923365,-1.3215534429867286,-0.5449670887544821,-0.1637002148171849,-0.6674474549492035,0.37846003298308656,-0.05119875428749204,0.14064504133157937,3.552612253770201,1.0624319661056087,1.3329848954478216,-0.8561099941928391,1.2664947720455977,1.6337937661071684,1.0393185235252296,0.37846003298308656,-0.7610185329208947,0.45564675544928607,2.30667735249979,-0.575347982490337,0.11361867633969869,-0.135372349749194,0.19432848633965574,-0.36591524642575174,2.30667735249979,-0.7296617004136831,5.100334225775537,0.7303321085557116,0.11361867633969869,-0.7296617004136831,-0.1637002148171849,1.7786774751475314,-0.6984719430678344,-0.36591524642575174,1.0624319661056087,1.7170158615945028,1.4421732031013788,0.05919085303596074,0.19432848633965574,0.7546817132763226,0.08646767296946187,1.0854555970140953,-1.1175185363069542,1.4204955543112385,-0.6674474549492035,1.8194332531953932,0.11361867633969869,0.32643528456534326 | 3,477 |
Glycosphingolipid metabolic process | 6 | 10 | 2.707356 | 0.006782 | Q99805,P06865,P16278,P06280,P04062,Q16739 | Processes and pathways | GO Biological process | msigdb_gobp | 129,198,40,212,125,191 | 125,212,198,1572,40,369,811,1457,191,129 | 1.8800487114656554,1.3549837745822957,1.4421732031013788,0.004254965933470663,3.143677150224885,0.8987110224111641,0.4043013153370249,0.05919085303596074,1.4852926279143495,1.8800487114656554 | 3,477 |
Abnormality of head blood vessel | 10 | 25 | 2.704625 | 0.006838 | P06865,P16278,P10619,P00846,Q9NZJ7,Q15056,P03886,Q13510,P07602,P17900 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 198,40,179,87,581,409,619,26,60,369 | 2080,949,842,87,619,2556,198,60,1572,179,2671,40,369,2337,646,2506,2509,2573,1524,26,409,1735,581,1753,1366 | -0.22076897182307467,0.3002497533746457,0.37846003298308656,2.3995294646169643,0.557016627936463,-0.45475787720939426,1.4421732031013788,2.757163757995302,0.004254965933470663,1.5706040688271496,-0.5147428618246798,3.143677150224885,0.8987110224111641,-0.3365974794064053,0.5318368798696025,-0.42499391779294676,-0.42499391779294676,-0.45475787720939426,0.03178702145824545,3.658124352450116,0.8271346805755291,-0.05119875428749204,0.6070563074848513,-0.05119875428749204,0.11361867633969869 | 3,477 |
Cholesterol metabolism | 10 | 25 | 2.694647 | 0.007046 | Q14739,Q15125,O76062,Q9UBM7,P04035,Q15392,Q15800,O15118,P04062,Q16850 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 224,100,69,205,235,170,314,85,125,95 | 85,771,69,913,2030,235,125,1510,3088,3271,326,1656,722,2104,2737,3330,224,100,3222,170,1465,314,95,205,1130 | 2.3995294646169643,0.43002989007773285,2.5631141361485468,0.32643528456534326,-0.19216530124130277,1.2664947720455977,1.8800487114656554,0.03178702145824545,-0.8561099941928391,-1.1847405024855464,0.992819324362481,-0.023406543396603797,0.48115289640719744,-0.22076897182307467,-0.5449670887544821,-1.3562641561568651,1.3329848954478216,2.250265534513931,-1.0510617648762144,1.6337937661071684,0.05919085303596074,1.0393185235252296,2.30667735249979,1.4204955543112385,0.22098784106991715 | 3,477 |
Predicted secreted proteins | 14 | 51 | 2.691957 | 0.007103 | O60888,Q15165,Q8WUJ1,P43490,P05067,Q9H9S5,Q9BTY2,Q9UM22,Q9UMX5,Q9HB40,Q08380,Q02818,P80303,Q9NZ08 | Functions | Protein Atlas Protein class | protein_atlas_protein_class | 65,194,67,227,102,232,169,14,46,16,206,83,25,92 | 1959,65,805,877,494,1571,102,2558,1438,2036,3450,2284,3392,2094,2673,1774,227,1580,2627,3327,722,2578,25,3465,1662,83,289,206,2404,1394,3354,194,1172,2992,1280,67,1938,3360,3433,448,976,169,2954,2374,397,232,16,92,14,46,1366 | -0.1637002148171849,2.669737999799437,0.4043013153370249,0.35250503124233246,0.7058818007064585,0.004254965933470663,2.2313425780094427,-0.45475787720939426,0.05919085303596074,-0.19216530124130277,-2.7679958875852217,-0.30742542710923365,-1.641656847170408,-0.22076897182307467,-0.5147428618246798,-0.0791229327418185,1.310904185408047,0.004254965933470663,-0.48467366246800686,-1.3562641561568651,0.48115289640719744,-0.45475787720939426,3.658124352450116,-4.2831543247856265,-0.023406543396603797,2.4362702098241025,1.0854555970140953,1.3987384981761122,-0.36591524642575174,0.08646767296946187,-1.4263119738467533,1.463772033506031,0.19432848633965574,-0.7296617004136831,0.14064504133157937,2.634407263051025,-0.135372349749194,-1.461654240448277,-2.137546621060343,0.7789314573393142,0.3002497533746457,1.654708681534299,-0.6984719430678344,-0.3365974794064053,0.8510897924183402,1.2887410211204224,4.173401607815876,2.3625615365785997,4.5844469972857,3.045222515298636,0.11361867633969869 | 3,477 |
Bulbar signs | 10 | 15 | 2.682327 | 0.007311 | Q15043,P06753,Q9NZJ7,Q99720,Q92734,P00846,Q9Y263,P07602,P04062,P35637 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 505,537,581,12,269,87,251,60,125,403 | 2086,87,619,2556,125,537,60,2560,403,1450,505,269,12,581,251 | -0.22076897182307467,2.3995294646169643,0.557016627936463,-0.45475787720939426,1.8800487114656554,0.6566756516668444,2.757163757995302,-0.45475787720939426,0.8271346805755291,0.05919085303596074,0.7058818007064585,1.1539946679655793,4.673528789411234,0.6070563074848513,1.2217504607212524 | 3,477 |
Alpha/Beta hydrolase fold [IPR029058] | 11 | 27 | 2.681681 | 0.007325 | P38571,Q9H6V9,P50897,P42785,Q9NUJ1,Q9H3G5,Q9HB40,Q8NCC3,P07099,P10619,Q9UMR5 | Sequence | InterPro Superfamily | interpro_homologous_superfamily | 189,2,36,7,110,15,16,17,80,179,56 | 2895,80,179,3245,3116,750,189,7,3071,2781,36,1530,3359,818,2473,261,17,634,3177,3276,3474,15,2,16,110,56,1559 | -0.6674474549492035,2.4727866020908955,1.5706040688271496,-1.1175185363069542,-0.8881537960438193,0.45564675544928607,1.4852926279143495,4.93319079393823,-0.8242407976278554,-0.575347982490337,3.2565382958940745,0.03178702145824545,-1.461654240448277,0.4043013153370249,-0.3953802206575081,1.1766660588890563,4.145899257701786,0.557016627936463,-0.9527730995631476,-1.1847405024855464,-7.011067236704793,4.362495893754808,5.6945455426912215,4.173401607815876,2.0387388219428937,2.8090134534356617,0.03178702145824545 | 3,477 |
Transporters | 114 | 396 | 2.6806 | 0.007349 | Q8WTV0,Q9P246,Q14108,Q99720,O43772,Q9Y619,Q9BSK2,P24390,P45880,P49755,Q8IXU6,P20020,P11717,Q9C0H2,Q96RL7,Q15363,Q9NZJ7,Q15629,Q96AA3,P07602,Q969E2,Q93050,Q6NTF9,O60637,Q8N511,Q5BJF2,O15118,Q8TCT8,O75381,O75787,O75915,O76024,Q5T3U5,P35670,P50416,P05067,Q6NUK1,P08183,P16615,O75844,P21281,Q99805,Q9H2V7,Q969V3,Q9Y3B3,Q8NEW0,Q96EE3,P51798,P56589,Q99523,Q15070,Q9Y4P1,Q9HD20,Q16739,Q9GZP9,P41440,Q16799,Q8WY22,Q9BTX1,P80723,P52292,Q16625,P04035,Q70HW3,Q9H061,Q9UJS0,Q9BRK5,Q9H2J7,Q9NV70,Q6N075,Q8IYU8,Q8N4V1,Q9UH99,Q07021,P30825,P13073,P98194,P04439,P40855,Q8TB61,Q96N66,Q9Y512,P11166,O95202,O15127,Q96A33,P36543,O75955,Q7Z3C6,Q9UBU6,Q9NRR5,Q15006,Q8IYI6,O96005,Q9UBX3,O00400,Q6P4A7,Q9BVL2,Q96PC5,Q15904,Q96NB2,Q8NFH4,Q16891,O60313,O75746,Q07065,Q9BZF1,Q4KMQ2,Q92544,Q9NRK6,Q92973,Q9UBV2,Q15043,P02786 | Functions | Protein Atlas Protein class | protein_atlas_protein_class | 3,533,11,12,22,550,548,27,29,538,38,553,552,48,577,54,581,58,573,60,571,72,602,74,79,84,85,89,585,586,587,588,98,593,594,102,632,112,621,123,623,129,130,659,133,137,662,135,163,175,182,183,185,191,196,199,200,203,218,215,213,225,235,242,246,250,264,272,274,267,268,284,295,289,298,297,313,318,319,320,332,336,325,324,322,342,349,347,364,367,366,371,383,379,398,387,410,425,423,442,449,445,463,453,454,458,487,479,510,515,512,517,505,494 | 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| 3,477 |
Respirasome | 10 | 47 | 2.67986 | 0.007365 | O43676,O95169,P14927,Q9UDW1,Q96CU9,Q6DKK2,Q9Y375,P14406,Q13423,O43674 | Localization | GO Cellular component | msigdb_gocc | 68,42,140,142,149,186,116,24,28,222 | 1369,642,452,222,68,3409,911,1832,843,2026,1251,561,42,2664,714,716,1142,619,2556,1639,2209,297,24,2285,140,1642,2212,845,1041,554,2902,2160,2624,2570,2297,28,3020,756,186,3254,149,1420,3256,142,1823,116,946 | 0.08646767296946187,0.5318368798696025,0.7546817132763226,1.3329848954478216,2.598866826737196,-1.7523935642470363,0.32643528456534326,-0.10718036336826706,0.37846003298308656,-0.19216530124130277,0.14064504133157937,0.6070563074848513,3.094651561884198,-0.5147428618246798,0.48115289640719744,0.48115289640719744,0.19432848633965574,0.557016627936463,-0.45475787720939426,-0.023406543396603797,-0.2783976197724557,1.0624319661056087,3.732375271475552,-0.30742542710923365,1.8194332531953932,-0.023406543396603797,-0.2783976197724557,0.37846003298308656,0.24752710744962664,0.6319180709039718,-0.6674474549492035,-0.24951260990209947,-0.48467366246800686,-0.45475787720939426,-0.30742542710923365,3.552612253770201,-0.7610185329208947,0.45564675544928607,1.5067355622428953,-1.1175185363069542,1.7786774751475314,0.08646767296946187,-1.1175185363069542,1.8194332531953932,-0.0791229327418185,2.01913202361103,0.32643528456534326 | 3,477 |
Glycosaminoglycan metabolism | 7 | 17 | 2.667936 | 0.007632 | Q8NCH0,P06865,P16278,Q8N6G5,Q96L58,P15586,P54802 | Processes and pathways | Reactome Pathways | msigdb_reactome | 128,198,40,278,152,121,94 | 1762,584,2495,2389,198,1572,1961,121,40,94,543,278,128,320,152,869,3107 | -0.0791229327418185,0.5820894631601891,-0.42499391779294676,-0.36591524642575174,1.4421732031013788,0.004254965933470663,-0.1637002148171849,1.9400536722511816,3.143677150224885,2.325363541577442,0.6566756516668444,1.1312362514820375,1.8800487114656554,1.0161145516991787,1.7581944914524472,0.37846003298308656,-0.8561099941928391 | 3,477 |
Golgi membrane | 49 | 146 | 2.651892 | 0.008004 | Q8NCH0,P10321,Q13464,P51790,Q9Y3B3,Q14108,Q08379,O00400,Q10472,Q9Y282,Q8N6G5,Q7LGA3,Q96L58,Q8N4V1,P24390,Q08378,Q92896,P49755,Q86Y82,Q15392,Q8IZA0,P11717,P98194,Q15363,Q15382,P04439,O95070,Q16739,Q8TB61,Q6NTF9,Q16799,Q9H7Z7,O43731,P53367,P11166,O60499,Q14789,P52292,O43505,O00461,Q9BVK6,Q13439,Q9H9S5,Q7Z3C6,Q9Y5Z9,O95197,Q9P2W9,Q8IV08,Q04721 | Localization | GO Cellular component | msigdb_gocc | 128,497,254,132,133,11,390,387,525,21,278,543,152,284,27,408,162,538,421,170,174,552,313,54,441,318,434,191,320,602,200,201,75,76,325,323,600,213,584,220,358,352,232,364,111,240,249,126,381 | 3216,387,220,2844,2771,2554,1500,948,2083,584,2999,75,2024,323,1505,1314,434,240,713,772,1766,318,644,1903,497,325,552,748,2562,27,1844,1257,593,2676,3070,1154,2046,3338,2048,538,1779,993,132,213,76,2572,2627,1159,2515,2821,2735,1260,1657,2342,682,2856,2226,1716,313,381,408,390,2860,3048,1977,525,2739,848,849,2107,352,254,11,600,3210,1056,2351,54,441,170,1854,2586,191,200,602,1926,543,364,2358,421,126,174,284,278,1405,1602,759,128,1280,1482,320,732,1535,2366,2246,162,1181,3275,152,733,2954,358,3291,1689,1355,3081,2485,1296,201,3057,232,2259,2761,1358,1748,2379,869,249,2962,1023,3107,798,2885,2653,1237,831,21,2076,1028,2769,1556,133,2324,1627,111,2384 | -1.0510617648762144,0.8510897924183402,1.3329848954478216,-0.6365864594340644,-0.575347982490337,-0.45475787720939426,0.03178702145824545,0.3002497533746457,-0.22076897182307467,0.5820894631601891,-0.7610185329208947,2.5271465892925953,-0.19216530124130277,0.992819324362481,0.03178702145824545,0.11361867633969869,0.7789314573393142,1.244164800335857,0.48115289640719744,0.43002989007773285,-0.0791229327418185,1.0161145516991787,0.5318368798696025,-0.135372349749194,0.7058818007064585,0.992819324362481,0.6319180709039718,0.45564675544928607,-0.45475787720939426,3.6431638120553607,-0.10718036336826706,0.14064504133157937,0.5820894631601891,-0.5147428618246798,-0.8242407976278554,0.19432848633965574,-0.19216530124130277,-1.3911828140592644,-0.19216530124130277,0.6566756516668444,-0.0791229327418185,0.2739473838070137,1.8599120159105682,1.3549837745822957,2.5271465892925953,-0.45475787720939426,-0.48467366246800686,0.19432848633965574,-0.42499391779294676,-0.6058872085760314,-0.5449670887544821,0.14064504133157937,-0.023406543396603797,-0.3365974794064053,0.5065492848540103,-0.6365864594340644,-0.2783976197724557,-0.05119875428749204,1.0393185235252296,0.8749483092866545,0.8271346805755291,0.8510897924183402,-0.6365864594340644,-0.7925442764842194,-0.1637002148171849,0.6813299364803377,-0.5449670887544821,0.37846003298308656,0.37846003298308656,-0.22076897182307467,0.9459521537888521,1.1992511003937982,4.673528789411234,0.5820894631601891,-1.0181148157260798,0.24752710744962664,-0.3365974794064053,2.8604185472495534,0.7789314573393142,1.6337937661071684,-0.10718036336826706,-0.45475787720939426,1.4852926279143495,1.4421732031013788,0.5820894631601891,-0.135372349749194,0.6566756516668444,0.9223787132780272,-0.3365974794064053,0.8030821726200548,1.8800487114656554,1.612805048617125,1.1083901252715689,1.1312362514820375,0.08646767296946187,0.004254965933470663,0.45564675544928607,1.8800487114656554,0.14064504133157937,0.05919085303596074,1.0161145516991787,0.48115289640719744,0.03178702145824545,-0.3365974794064053,-0.2783976197724557,1.6963192103002542,0.19432848633965574,-1.1847405024855464,1.7581944914524472,0.48115289640719744,-0.6984719430678344,0.9459521537888521,-1.2186440927684283,-0.023406543396603797,0.11361867633969869,-0.8242407976278554,-0.3953802206575081,0.14064504133157937,1.4421732031013788,-0.7925442764842194,1.2887410211204224,-0.2783976197724557,-0.5449670887544821,0.11361867633969869,-0.05119875428749204,-0.3365974794064053,0.37846003298308656,1.2217504607212524,-0.6984719430678344,0.2739473838070137,-0.8561099941928391,0.43002989007773285,-0.6365864594340644,-0.48467366246800686,0.16754792955183684,0.4043013153370249,3.8781904571384658,-0.19216530124130277,0.2739473838070137,-0.5449670887544821,0.03178702145824545,1.8599120159105682,-0.30742542710923365,0.004254965933470663,2.0387388219428937,-0.3365974794064053 | 3,477 |
Transport of small molecules | 48 | 167 | 2.630324 | 0.00853 | Q8WTV0,P51790,Q9UBX3,Q8NEW0,P51798,Q9H2J7,Q13546,P30519,O00400,Q8IYU8,Q99623,Q8N4V1,P28074,P45880,P21796,P56589,P49721,P02794,P30825,Q9C0H2,Q15904,P09601,P98194,Q9HD20,P40855,Q8TB61,P38571,Q9GZP9,Q9Y5K8,Q93050,P11166,O95202,P28072,O00231,O15118,Q9Y487,Q5T3U5,Q4KMQ2,P36543,P28070,O00233,P60900,P08183,Q70HW3,Q9NRK6,Q9UBV2,Q15043,Q99576 | Processes and pathways | Reactome Pathways | msigdb_reactome | 3,132,398,137,135,272,391,13,387,268,413,284,283,29,33,163,37,418,298,48,442,52,313,185,319,320,189,196,471,72,325,324,208,321,85,359,98,479,349,348,472,363,112,242,515,517,505,384 | 321,2326,472,387,2807,1892,85,2441,986,1139,2847,1896,771,3218,3183,913,1899,324,2668,494,418,1317,1036,1086,1703,1769,112,1439,2152,52,1145,325,880,1038,2210,621,2211,1442,553,1838,1040,623,2093,2338,33,1643,2900,991,2214,3295,3205,348,208,283,1256,13,2453,298,1515,774,3271,1044,1650,1257,593,2217,3040,349,189,1707,319,1777,29,2047,2510,37,2099,132,135,1712,776,2165,652,2909,3248,163,363,754,2628,722,1454,2167,2459,3273,2346,1390,595,313,2104,2686,1051,848,887,2740,391,1665,2406,2789,2916,2690,505,1400,442,479,98,1061,818,242,2417,2870,268,284,2831,2125,1281,137,320,3,2365,788,2247,72,2425,1685,930,2372,2532,384,413,1013,1540,1807,2430,2065,48,196,737,272,1015,185,515,517,398,937,870,1752,612,613,2075,2381,982,872,359,873,471,834,3324 | 0.992819324362481,-0.3365974794064053,0.7303321085557116,0.8510897924183402,-0.6058872085760314,-0.135372349749194,2.3995294646169643,-0.3953802206575081,0.2739473838070137,0.19432848633965574,-0.6365864594340644,-0.135372349749194,0.43002989007773285,-1.0510617648762144,-0.9853526277263864,0.32643528456534326,-0.135372349749194,0.992819324362481,-0.5147428618246798,0.7058818007064585,0.8030821726200548,0.11361867633969869,0.24752710744962664,0.22098784106991715,-0.05119875428749204,-0.0791229327418185,2.01913202361103,0.05919085303596074,-0.24951260990209947,2.8944454237079458,0.19432848633965574,0.992819324362481,0.35250503124233246,0.24752710744962664,-0.2783976197724557,0.557016627936463,-0.2783976197724557,0.05919085303596074,0.6319180709039718,-0.10718036336826706,0.24752710744962664,0.557016627936463,-0.22076897182307467,-0.3365974794064053,3.42971985718421,-0.023406543396603797,-0.6674474549492035,0.2739473838070137,-0.2783976197724557,-1.2527458541591188,-1.0181148157260798,0.9459521537888521,1.3769014390666614,1.1083901252715689,0.14064504133157937,4.622785168296892,-0.3953802206575081,1.0624319661056087,0.03178702145824545,0.43002989007773285,-1.1847405024855464,0.24752710744962664,-0.023406543396603797,0.14064504133157937,0.5820894631601891,-0.2783976197724557,-0.7925442764842194,0.9459521537888521,1.4852926279143495,-0.05119875428749204,1.0161145516991787,-0.0791229327418185,3.5373871392999625,-0.19216530124130277,-0.42499391779294676,3.2405444325098856,-0.22076897182307467,1.8599120159105682,1.8397070212293376,-0.05119875428749204,0.43002989007773285,-0.24951260990209947,0.5318368798696025,-0.6674474549492035,-1.1175185363069542,1.6755503223412216,0.9223787132780272,0.45564675544928607,-0.48467366246800686,0.48115289640719744,0.05919085303596074,-0.24951260990209947,-0.3953802206575081,-1.1847405024855464,-0.3365974794064053,0.08646767296946187,0.5820894631601891,1.0393185235252296,-0.22076897182307467,-0.5147428618246798,0.24752710744962664,0.37846003298308656,0.35250503124233246,-0.5449670887544821,0.8510897924183402,-0.023406543396603797,-0.36591524642575174,-0.575347982490337,-0.6674474549492035,-0.5147428618246798,0.7058818007064585,0.08646767296946187,0.7789314573393142,0.7303321085557116,2.269128727200785,0.24752710744962664,0.4043013153370249,1.244164800335857,-0.36591524642575174,-0.6365864594340644,1.1539946679655793,1.1083901252715689,-0.6058872085760314,-0.22076897182307467,0.14064504133157937,1.8397070212293376,1.0161145516991787,5.112099164366075,-0.3365974794064053,0.43002989007773285,-0.2783976197724557,2.5631141361485468,-0.36591524642575174,-0.023406543396603797,0.32643528456534326,-0.3365974794064053,-0.42499391779294676,0.8749483092866545,0.8271346805755291,0.2739473838070137,0.03178702145824545,-0.0791229327418185,-0.36591524642575174,-0.19216530124130277,2.9953831789273684,1.463772033506031,0.48115289640719744,1.1539946679655793,0.2739473838070137,1.5281014060315,0.7058818007064585,0.7058818007064585,0.8510897924183402,0.32643528456534326,0.37846003298308656,-0.05119875428749204,0.5820894631601891,0.5820894631601891,-0.19216530124130277,-0.3365974794064053,0.3002497533746457,0.37846003298308656,0.9459521537888521,0.37846003298308656,0.7546817132763226,0.4043013153370249,-1.3215534429867286 | 3,477 |
Intracellular calcium-sensing protein | 8 | 15 | 2.621045 | 0.008766 | Q14257,Q9BRK5,O43852,Q02818,P41208,Q15293,P80303,P0DP25 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 164,264,234,83,118,151,25,122 | 234,122,3371,118,3123,25,83,164,151,3099,927,268,1676,1807,264 | 1.2664947720455977,1.9201190775732102,-1.5329887599381864,1.9797239596761134,-0.8881537960438193,3.658124352450116,2.4362702098241025,1.6755503223412216,1.7581944914524472,-0.8561099941928391,0.32643528456534326,1.1539946679655793,-0.023406543396603797,-0.0791229327418185,1.1766660588890563 | 3,477 |
Calmodulin | 8 | 15 | 2.621045 | 0.008766 | Q14257,Q9BRK5,O43852,Q02818,P41208,Q15293,P80303,P0DP25 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 164,264,234,83,118,151,25,122 | 234,122,3371,118,3123,25,83,164,151,3099,927,268,1676,1807,264 | 1.2664947720455977,1.9201190775732102,-1.5329887599381864,1.9797239596761134,-0.8881537960438193,3.658124352450116,2.4362702098241025,1.6755503223412216,1.7581944914524472,-0.8561099941928391,0.32643528456534326,1.1539946679655793,-0.023406543396603797,-0.0791229327418185,1.1766660588890563 | 3,477 |
Passive transmembrane transporter activity | 13 | 36 | 2.619496 | 0.008806 | P21796,Q4KMQ2,P51790,Q9P246,P51798,O75964,P48047,Q9C0H2,P00846,O75947,P56385,P45880,P06576 | Functions | GO Molecular function | msigdb_gomf | 33,479,132,533,135,43,555,48,87,433,405,29,495 | 3335,433,43,1437,87,495,1438,3065,1903,33,591,1647,957,1707,3336,29,555,132,135,753,405,1658,2913,1457,479,2870,1281,1410,733,1013,1808,48,533,1237,982,3084 | -1.3911828140592644,0.7789314573393142,3.078220375517014,0.05919085303596074,2.3995294646169643,0.7058818007064585,0.05919085303596074,-0.8242407976278554,-0.135372349749194,3.42971985718421,0.5820894631601891,-0.023406543396603797,0.3002497533746457,-0.05119875428749204,-1.3911828140592644,3.5373871392999625,0.6319180709039718,1.8599120159105682,1.8397070212293376,0.45564675544928607,0.8271346805755291,-0.023406543396603797,-0.6674474549492035,0.05919085303596074,0.7303321085557116,-0.6365864594340644,0.14064504133157937,0.08646767296946187,0.48115289640719744,0.2739473838070137,-0.0791229327418185,2.9953831789273684,0.6813299364803377,0.16754792955183684,0.3002497533746457,-0.8242407976278554 | 3,477 |
Cholesterol biosynthesis | 8 | 16 | 2.618334 | 0.008836 | Q14739,Q15125,O76062,Q9UBM7,P04035,Q15392,Q15800,Q16850 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 224,100,69,205,235,170,314,95 | 69,2030,235,1510,326,1656,2737,3330,224,100,3222,170,1465,314,95,205 | 2.5631141361485468,-0.19216530124130277,1.2664947720455977,0.03178702145824545,0.992819324362481,-0.023406543396603797,-0.5449670887544821,-1.3562641561568651,1.3329848954478216,2.250265534513931,-1.0510617648762144,1.6337937661071684,0.05919085303596074,1.0393185235252296,2.30667735249979,1.4204955543112385 | 3,477 |
Horizontal nystagmus | 10 | 23 | 2.615442 | 0.008911 | P52815,O60313,O95831,P00846,Q9NZJ7,Q9NSE4,Q9H061,P04062,P07602,O14773 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 380,453,146,87,581,516,246,125,60,221 | 1368,985,221,453,913,146,87,125,60,622,751,380,1974,2223,2746,1007,1684,246,516,2837,1750,581,1425 | 0.08646767296946187,0.2739473838070137,1.3329848954478216,0.7546817132763226,0.32643528456534326,1.7786774751475314,2.3995294646169643,1.8800487114656554,2.757163757995302,0.557016627936463,0.45564675544928607,0.8749483092866545,-0.1637002148171849,-0.2783976197724557,-0.5449670887544821,0.2739473838070137,-0.023406543396603797,1.2217504607212524,0.7058818007064585,-0.6058872085760314,-0.05119875428749204,0.6070563074848513,0.08646767296946187 | 3,477 |
Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen | 10 | 34 | 2.615208 | 0.008917 | P13674,O15460,Q32P28,Q14534,P30519,Q8NB78,Q15800,P09601,Q16850,Q6UW02 | Functions | GO Molecular function | msigdb_gomf | 253,157,392,300,13,114,314,52,95,192 | 1759,1760,400,157,2025,1959,2717,2774,519,951,1769,52,253,1087,1513,13,2575,1717,887,300,314,95,392,1475,192,1672,926,3447,114,793,2758,707,2077,1365 | -0.0791229327418185,-0.0791229327418185,0.8271346805755291,1.6963192103002542,-0.19216530124130277,-0.1637002148171849,-0.5449670887544821,-0.575347982490337,0.6813299364803377,0.3002497533746457,-0.0791229327418185,2.8944454237079458,1.1992511003937982,0.22098784106991715,0.03178702145824545,4.622785168296892,-0.45475787720939426,-0.05119875428749204,0.35250503124233246,1.0624319661056087,1.0393185235252296,2.30667735249979,0.8510897924183402,0.05919085303596074,1.4852926279143495,-0.023406543396603797,0.32643528456534326,-2.6798572045062157,2.01913202361103,0.43002989007773285,-0.5449670887544821,0.5065492848540103,-0.19216530124130277,0.11361867633969869 | 3,477 |
Respiratory distress | 19 | 57 | 2.608336 | 0.009098 | P16219,O95831,Q96L58,Q9Y619,Q13510,O95169,P49419,P53701,Q9NZJ7,P23786,Q5F1R6,P07602,P10253,Q9UHX1,P00846,Q96EY8,P03886,P04062,P21281 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 498,146,152,550,26,42,45,181,581,310,443,60,202,81,87,484,619,125,623 | 1374,1502,2809,1830,843,1568,42,146,87,619,2556,125,60,644,202,3234,498,623,2899,2934,310,1321,2454,45,3172,3437,1383,2297,2398,1259,181,2050,1916,1325,996,3048,2405,26,1397,1987,852,443,898,1734,2874,1181,1737,484,152,1352,3417,1232,1420,581,81,1824,550 | 0.08646767296946187,0.03178702145824545,-0.6058872085760314,-0.10718036336826706,0.37846003298308656,0.004254965933470663,3.094651561884198,1.7786774751475314,2.3995294646169643,0.557016627936463,-0.45475787720939426,1.8800487114656554,2.757163757995302,0.5318368798696025,1.4204955543112385,-1.084195613202823,0.7058818007064585,0.557016627936463,-0.6674474549492035,-0.6984719430678344,1.0393185235252296,0.11361867633969869,-0.3953802206575081,3.061744110987097,-0.9527730995631476,-2.340159185109549,0.08646767296946187,-0.30742542710923365,-0.36591524642575174,0.14064504133157937,1.5493907225373234,-0.19216530124130277,-0.135372349749194,0.11361867633969869,0.2739473838070137,-0.7925442764842194,-0.36591524642575174,3.658124352450116,0.08646767296946187,-0.1637002148171849,0.37846003298308656,0.7789314573393142,0.35250503124233246,-0.05119875428749204,-0.6365864594340644,0.19432848633965574,-0.05119875428749204,0.7303321085557116,1.7581944914524472,0.11361867633969869,-1.7897795234170681,0.16754792955183684,0.08646767296946187,0.6070563074848513,2.4727866020908955,-0.0791229327418185,0.6566756516668444 | 3,477 |
Visual loss | 14 | 57 | 2.601394 | 0.009285 | O15460,P50897,P51798,P07602,Q92734,Q15051,O75503,P53701,P00846,P48449,Q8IY17,A2RRP1,P04439,O14773 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 157,36,135,60,269,176,20,181,87,55,444,337,318,221 | 337,1955,3166,3111,985,221,157,453,843,1896,20,1083,2662,1142,3259,87,1766,619,2556,2334,318,60,2032,2669,2285,1906,2337,1644,1043,2567,2676,1708,55,36,2098,135,1452,181,3393,780,848,1590,2347,725,2307,176,3332,444,1994,269,691,1228,1352,2427,1420,581,834 | 0.9694321064173009,-0.1637002148171849,-0.9527730995631476,-0.8881537960438193,0.2739473838070137,1.3329848954478216,1.6963192103002542,0.7546817132763226,0.37846003298308656,-0.135372349749194,3.935544376605113,0.22098784106991715,-0.5147428618246798,0.19432848633965574,-1.151032748253348,2.3995294646169643,-0.0791229327418185,0.557016627936463,-0.45475787720939426,-0.3365974794064053,1.0161145516991787,2.757163757995302,-0.19216530124130277,-0.5147428618246798,-0.30742542710923365,-0.135372349749194,-0.3365974794064053,-0.023406543396603797,0.24752710744962664,-0.45475787720939426,-0.5147428618246798,-0.05119875428749204,2.8261975000437003,3.2565382958940745,-0.22076897182307467,1.8397070212293376,0.05919085303596074,1.5493907225373234,-1.641656847170408,0.43002989007773285,0.37846003298308656,0.004254965933470663,-0.3365974794064053,0.48115289640719744,-0.30742542710923365,1.591741995868226,-1.3562641561568651,0.7789314573393142,-0.1637002148171849,1.1539946679655793,0.5065492848540103,0.16754792955183684,0.11361867633969869,-0.36591524642575174,0.08646767296946187,0.6070563074848513,0.4043013153370249 | 3,477 |
Oxidoreductase activity acting on the ch ch group of donors nad or nadp as acceptor | 7 | 12 | 2.596862 | 0.009408 | Q14739,Q8N4Q0,O76062,Q9H7Z7,Q9UBM7,Q15392,Q9BY49 | Functions | GO Molecular function | msigdb_gomf | 224,4,69,201,205,170,156 | 69,2781,2732,224,3095,170,4,482,156,201,294,205 | 2.5631141361485468,-0.575347982490337,-0.5449670887544821,1.3329848954478216,-0.8561099941928391,1.6337937661071684,5.100334225775537,0.7303321085557116,1.7170158615945028,1.4421732031013788,1.0854555970140953,1.4204955543112385 | 3,477 |
Nuclear inner membrane | 8 | 23 | 2.587726 | 0.009661 | Q14739,Q14728,O76062,Q99720,Q9Y2U8,O75844,Q9H1E5,Q9UH99 | Localization | GO Cellular component | msigdb_gocc | 224,260,69,12,377,123,256,295 | 123,69,677,622,1846,1450,808,3406,778,654,1329,260,224,2524,1275,372,1677,1998,12,2131,256,295,377 | 1.900117577201474,2.5631141361485468,0.5065492848540103,0.557016627936463,-0.10718036336826706,0.05919085303596074,0.4043013153370249,-1.7152465177215432,0.43002989007773285,0.5318368798696025,0.11361867633969869,1.1766660588890563,1.3329848954478216,-0.42499391779294676,0.14064504133157937,0.8987110224111641,-0.023406543396603797,-0.1637002148171849,4.673528789411234,-0.22076897182307467,1.1992511003937982,1.0854555970140953,0.8987110224111641 | 3,477 |
Increased bone mineral density | 9 | 27 | 2.583685 | 0.009775 | Q14739,Q15125,Q13126,P51798,Q14108,Q15392,Q9Y2U8,P04062,P54802 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 224,100,70,135,11,170,377,125,94 | 842,952,125,2620,1837,2851,2973,2506,2509,135,94,3248,1524,3174,70,726,11,755,224,505,409,100,170,2114,1753,377,1366 | 0.37846003298308656,0.3002497533746457,1.8800487114656554,-0.48467366246800686,-0.10718036336826706,-0.6365864594340644,-0.7296617004136831,-0.42499391779294676,-0.42499391779294676,1.8397070212293376,2.325363541577442,-1.1175185363069542,0.03178702145824545,-0.9527730995631476,2.5631141361485468,0.48115289640719744,4.673528789411234,0.45564675544928607,1.3329848954478216,0.7058818007064585,0.8271346805755291,2.250265534513931,1.6337937661071684,-0.22076897182307467,-0.05119875428749204,0.8987110224111641,0.11361867633969869 | 3,477 |
Sterol metabolism | 10 | 27 | 2.582451 | 0.00981 | Q14739,Q15125,O76062,Q9UBM7,P04035,Q15392,Q15800,O15118,P04062,Q16850 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 224,100,69,205,235,170,314,85,125,95 | 85,771,519,69,913,2030,235,125,1510,3088,3271,326,1656,722,2104,2737,3330,224,100,3222,170,1465,314,95,205,1130,870 | 2.3995294646169643,0.43002989007773285,0.6813299364803377,2.5631141361485468,0.32643528456534326,-0.19216530124130277,1.2664947720455977,1.8800487114656554,0.03178702145824545,-0.8561099941928391,-1.1847405024855464,0.992819324362481,-0.023406543396603797,0.48115289640719744,-0.22076897182307467,-0.5449670887544821,-1.3562641561568651,1.3329848954478216,2.250265534513931,-1.0510617648762144,1.6337937661071684,0.05919085303596074,1.0393185235252296,2.30667735249979,1.4204955543112385,0.22098784106991715,0.37846003298308656 | 3,477 |
Transition metal ion transport | 9 | 16 | 2.582381 | 0.009812 | Q8NEW0,Q07960,O15173,P02794,P98194,Q15043,Q8N4V1,Q9HD20,P02786 | Processes and pathways | GO Biological process | msigdb_gobp | 137,231,134,418,313,505,284,185,494 | 134,1139,494,418,593,1779,313,2686,1265,231,505,284,137,1690,185,834 | 1.8397070212293376,0.19432848633965574,0.7058818007064585,0.8030821726200548,0.5820894631601891,-0.0791229327418185,1.0393185235252296,-0.5147428618246798,0.14064504133157937,1.2887410211204224,0.7058818007064585,1.1083901252715689,1.8397070212293376,-0.023406543396603797,1.5281014060315,0.4043013153370249 | 3,477 |
Atpase coupled transmembrane transporter activity | 12 | 26 | 2.580438 | 0.009867 | Q5T3U5,P35670,Q9Y5K8,P36543,P51798,P20020,P08183,Q9NRK6,P98194,P16615,Q9HD20,P06576 | Functions | GO Molecular function | msigdb_gomf | 98,593,471,349,135,553,112,515,313,621,185,495 | 2441,1139,2847,1036,495,112,621,553,623,2093,1643,1256,1515,593,349,1707,135,2628,313,3250,1526,98,185,515,1752,471 | -0.3953802206575081,0.19432848633965574,-0.6365864594340644,0.24752710744962664,0.7058818007064585,2.01913202361103,0.557016627936463,0.6319180709039718,0.557016627936463,-0.22076897182307467,-0.023406543396603797,0.14064504133157937,0.03178702145824545,0.5820894631601891,0.9459521537888521,-0.05119875428749204,1.8397070212293376,-0.48467366246800686,1.0393185235252296,-1.1175185363069542,0.03178702145824545,2.269128727200785,1.5281014060315,0.7058818007064585,-0.05119875428749204,0.7546817132763226 | 3,477 |
Regulation of autophagy | 23 | 101 | 2.575306 | 0.010015 | Q13464,Q9NV70,Q08379,Q86UE4,Q9H444,P21796,O00165,P10619,P09601,O43464,Q15382,P07602,P30536,P19474,Q93050,P27544,O15118,Q9Y487,P36543,Q9NRR5,O75844,P04062,Q8IYI6 | Processes and pathways | GO Biological process | msigdb_gobp | 254,274,390,411,293,33,49,179,52,307,441,60,61,435,72,78,85,359,349,366,123,125,383 | 49,1245,985,2022,85,1137,1432,2275,307,2847,1314,2027,123,1569,520,125,3357,3064,3145,1086,1638,1770,60,2035,644,2036,52,179,880,2211,435,2777,623,2093,33,3006,78,61,1043,349,1707,2568,1154,1970,2218,3296,2396,2511,2735,2628,2102,2913,1589,2785,684,390,1395,254,2174,2407,441,2177,1531,411,1220,1601,383,1799,1110,1346,3194,1535,1179,72,3390,1998,1866,1010,1999,3241,1687,2190,293,2880,1815,3104,366,274,2139,669,581,1235,3105,1752,2548,832,1073,1556,359,471,945 | 2.961925562747231,0.14064504133157937,0.2739473838070137,-0.19216530124130277,2.3995294646169643,0.19432848633965574,0.05919085303596074,-0.30742542710923365,1.0393185235252296,-0.6365864594340644,0.11361867633969869,-0.19216530124130277,1.900117577201474,0.004254965933470663,0.6813299364803377,1.8800487114656554,-1.461654240448277,-0.8242407976278554,-0.9203741657960346,0.22098784106991715,-0.023406543396603797,-0.0791229327418185,2.757163757995302,-0.19216530124130277,0.5318368798696025,-0.19216530124130277,2.8944454237079458,1.5706040688271496,0.35250503124233246,-0.2783976197724557,0.7789314573393142,-0.575347982490337,0.557016627936463,-0.22076897182307467,3.42971985718421,-0.7610185329208947,2.4909615357157167,2.7397803638415104,0.24752710744962664,0.9459521537888521,-0.05119875428749204,-0.45475787720939426,0.19432848633965574,-0.1637002148171849,-0.2783976197724557,-1.2527458541591188,-0.36591524642575174,-0.42499391779294676,-0.5449670887544821,-0.48467366246800686,-0.22076897182307467,-0.6674474549492035,0.004254965933470663,-0.575347982490337,0.5065492848540103,0.8510897924183402,0.08646767296946187,1.1992511003937982,-0.24951260990209947,-0.36591524642575174,0.7789314573393142,-0.24951260990209947,0.03178702145824545,0.8271346805755291,0.16754792955183684,0.004254965933470663,0.8749483092866545,-0.0791229327418185,0.22098784106991715,0.11361867633969869,-0.9853526277263864,0.03178702145824545,0.19432848633965574,2.5631141361485468,-1.6052082141099608,-0.1637002148171849,-0.10718036336826706,0.2739473838070137,-0.1637002148171849,-1.084195613202823,-0.023406543396603797,-0.24951260990209947,1.0854555970140953,-0.6365864594340644,-0.0791229327418185,-0.8561099941928391,0.9223787132780272,1.1539946679655793,-0.22076897182307467,0.5318368798696025,0.6070563074848513,0.16754792955183684,-0.8561099941928391,-0.05119875428749204,-0.42499391779294676,0.4043013153370249,0.24752710744962664,0.03178702145824545,0.9459521537888521,0.7546817132763226,0.32643528456534326 | 3,477 |
Hormone metabolic process | 7 | 31 | 2.574763 | 0.010031 | Q53GQ0,O95470,O94788,Q9HB40,P42892,O75844,P30536 | Processes and pathways | GO Biological process | msigdb_gobp | 165,139,77,16,53,123,61 | 2716,586,123,77,2389,139,1036,2284,3351,1087,61,53,3072,2098,3013,1985,2826,165,784,2528,1731,1994,2183,2596,2949,2427,16,466,205,1425,2611 | -0.5449670887544821,0.5820894631601891,1.900117577201474,2.4909615357157167,-0.36591524642575174,1.8194332531953932,0.24752710744962664,-0.30742542710923365,-1.4263119738467533,0.22098784106991715,2.7397803638415104,2.8944454237079458,-0.8242407976278554,-0.22076897182307467,-0.7610185329208947,-0.1637002148171849,-0.6058872085760314,1.6755503223412216,0.43002989007773285,-0.42499391779294676,-0.05119875428749204,-0.1637002148171849,-0.24951260990209947,-0.45475787720939426,-0.6984719430678344,-0.36591524642575174,4.173401607815876,0.7546817132763226,1.4204955543112385,0.08646767296946187,-0.45475787720939426 | 3,477 |
Cardiac muscle contraction | 9 | 19 | 2.572398 | 0.0101 | P06753,P14927,P22695,Q9UDW1,P13073,O14949,P16615,P14406,P67936 | Processes and pathways | KEGG Pathways | msigdb_kegg | 537,140,554,142,297,452,621,24,406 | 642,452,1142,1036,537,1639,2209,297,24,2285,140,1642,621,845,554,2624,2165,406,142 | 0.5318368798696025,0.7546817132763226,0.19432848633965574,0.24752710744962664,0.6566756516668444,-0.023406543396603797,-0.2783976197724557,1.0624319661056087,3.732375271475552,-0.30742542710923365,1.8194332531953932,-0.023406543396603797,0.557016627936463,0.37846003298308656,0.6319180709039718,-0.48467366246800686,-0.24951260990209947,0.8271346805755291,1.8194332531953932 | 3,477 |
Sterol biosynthesis | 8 | 18 | 2.571035 | 0.01014 | Q14739,Q15125,O76062,Q9UBM7,P04035,Q15392,Q15800,Q16850 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 224,100,69,205,235,170,314,95 | 519,69,2030,235,1510,326,1656,2737,3330,224,100,3222,170,1465,314,95,205,870 | 0.6813299364803377,2.5631141361485468,-0.19216530124130277,1.2664947720455977,0.03178702145824545,0.992819324362481,-0.023406543396603797,-0.5449670887544821,-1.3562641561568651,1.3329848954478216,2.250265534513931,-1.0510617648762144,1.6337937661071684,0.05919085303596074,1.0393185235252296,2.30667735249979,1.4204955543112385,0.37846003298308656 | 3,477 |
transporter | 20 | 58 | 2.566034 | 0.010287 | Q99595,Q99805,Q9H2V7,O60830,O43615,Q96EE3,Q6N075,O43772,Q9Y619,Q9H2D1,Q96P70,Q15070,Q8NFH4,P41440,Q9HD45,Q9UJZ1,P52292,Q92544,Q92973,Q567V2 | Functions | Panther Protein class | panther_protein_class | 0,129,130,1,378,662,267,22,550,699,693,182,445,199,467,612,213,510,512,241 | 2271,2714,2890,2771,2715,2330,378,2086,22,1,2896,1634,1321,751,3336,199,3338,1322,213,1385,1386,2398,776,2049,994,995,1658,2229,2236,182,241,267,858,689,2244,445,1936,1732,510,512,662,693,1290,0,129,1540,2953,2650,699,130,2541,467,978,3321,2838,612,944,550 | -0.30742542710923365,-0.5449670887544821,-0.6674474549492035,-0.575347982490337,-0.5449670887544821,-0.3365974794064053,0.8749483092866545,-0.22076897182307467,3.834814628505806,5.715874196634267,-0.6674474549492035,-0.023406543396603797,0.11361867633969869,0.45564675544928607,-1.3911828140592644,1.4421732031013788,-1.3911828140592644,0.11361867633969869,1.3549837745822957,0.08646767296946187,0.08646767296946187,-0.36591524642575174,0.43002989007773285,-0.19216530124130277,0.2739473838070137,0.2739473838070137,-0.023406543396603797,-0.2783976197724557,-0.2783976197724557,1.5493907225373234,1.244164800335857,1.1539946679655793,0.37846003298308656,0.5065492848540103,-0.2783976197724557,0.7789314573393142,-0.135372349749194,-0.05119875428749204,0.7058818007064585,0.7058818007064585,0.5318368798696025,0.5065492848540103,0.14064504133157937,5.883876178508293,1.8800487114656554,0.03178702145824545,-0.6984719430678344,-0.48467366246800686,0.5065492848540103,1.8800487114656554,-0.42499391779294676,0.7546817132763226,0.3002497533746457,-1.3215534429867286,-0.6058872085760314,0.5820894631601891,0.32643528456534326,0.6566756516668444 | 3,477 |
Aminoglycan metabolic process | 6 | 17 | 2.563085 | 0.010375 | Q8NCH0,P06865,P16278,Q96L58,P15586,P54802 | Processes and pathways | GO Biological process | msigdb_gobp | 128,198,40,152,121,94 | 584,2443,2668,717,198,1572,1961,121,40,94,2686,543,278,128,152,1128,869 | 0.5820894631601891,-0.3953802206575081,-0.5147428618246798,0.48115289640719744,1.4421732031013788,0.004254965933470663,-0.1637002148171849,1.9400536722511816,3.143677150224885,2.325363541577442,-0.5147428618246798,0.6566756516668444,1.1312362514820375,1.8800487114656554,1.7581944914524472,0.22098784106991715,0.37846003298308656 | 3,477 |
Fad binding | 6 | 11 | 2.561439 | 0.010424 | Q14534,Q15067,Q15392,Q8NB78,O95831,O00116 | Functions | GO Molecular function | msigdb_gomf | 300,237,170,114,146,119 | 119,306,146,2030,300,237,170,114,2949,870,1365 | 1.9599218161866019,1.0393185235252296,1.7786774751475314,-0.19216530124130277,1.0624319661056087,1.2664947720455977,1.6337937661071684,2.01913202361103,-0.6984719430678344,0.37846003298308656,0.11361867633969869 | 3,477 |
Receptor | 6 | 31 | 2.558957 | 0.010499 | Q8WTV0,Q9GZP9,A6NIH7,Q14108,Q9UQB8,Q13432 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 3,196,9,11,57,62 | 9,2715,2024,585,586,1899,2668,1509,552,2157,3336,1652,2860,62,11,3274,241,602,1670,3,1347,3403,2065,196,2541,1357,978,2142,3349,57,1954 | 4.736367487081506,-0.5449670887544821,-0.19216530124130277,0.5820894631601891,0.5820894631601891,-0.135372349749194,-0.5147428618246798,0.03178702145824545,0.6319180709039718,-0.24951260990209947,-1.3911828140592644,-0.023406543396603797,-0.6365864594340644,2.7397803638415104,4.673528789411234,-1.1847405024855464,1.244164800335857,0.5820894631601891,-0.023406543396603797,5.112099164366075,0.11361867633969869,-1.6783352899588402,-0.19216530124130277,1.463772033506031,-0.42499391779294676,0.11361867633969869,0.3002497533746457,-0.22076897182307467,-1.3911828140592644,2.8090134534356617,-0.135372349749194 | 3,477 |
Abnormality of epiphysis morphology | 20 | 64 | 2.557189 | 0.010552 | P51798,O95831,Q7LGA3,Q96L58,P56589,P16278,O96028,Q15051,Q96DX4,Q5F1R6,P40855,Q8WVQ1,Q9UBM7,O95202,Q96HY6,Q14739,Q15125,P38435,Q9Y2U8,O00116 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 135,146,543,152,163,40,296,176,448,443,319,465,205,324,485,224,100,361,377,119 | 119,2022,2082,1959,2894,585,1568,1376,324,618,146,2089,296,1961,1145,40,1087,2851,1149,2566,1651,361,2394,319,135,1655,163,2050,1586,3261,723,3013,1590,2349,224,2464,176,100,1465,443,1856,966,1927,543,2868,2529,465,1734,448,3414,485,152,1614,1015,3030,3314,205,829,941,2841,3266,377,1824,550 | 1.9599218161866019,-0.19216530124130277,-0.22076897182307467,-0.1637002148171849,-0.6674474549492035,0.5820894631601891,0.004254965933470663,0.08646767296946187,0.992819324362481,0.557016627936463,1.7786774751475314,-0.22076897182307467,1.0624319661056087,-0.1637002148171849,0.19432848633965574,3.143677150224885,0.22098784106991715,-0.6365864594340644,0.19432848633965574,-0.45475787720939426,-0.023406543396603797,0.9223787132780272,-0.36591524642575174,1.0161145516991787,1.8397070212293376,-0.023406543396603797,1.6755503223412216,-0.19216530124130277,0.004254965933470663,-1.151032748253348,0.48115289640719744,-0.7610185329208947,0.004254965933470663,-0.3365974794064053,1.3329848954478216,-0.3953802206575081,1.591741995868226,2.250265534513931,0.05919085303596074,0.7789314573393142,-0.10718036336826706,0.3002497533746457,-0.135372349749194,0.6566756516668444,-0.6365864594340644,-0.42499391779294676,0.7546817132763226,-0.05119875428749204,0.7789314573393142,-1.7523935642470363,0.7303321085557116,1.7581944914524472,0.004254965933470663,0.2739473838070137,-0.7610185329208947,-1.2870481640073945,1.4204955543112385,0.4043013153370249,0.32643528456534326,-0.6058872085760314,-1.151032748253348,0.8987110224111641,-0.0791229327418185,0.6566756516668444 | 3,477 |
Protease | 21 | 91 | 2.546684 | 0.010875 | P42785,Q9H3G5,Q9HB40,P28074,Q9UIQ6,P10619,P42892,P67812,Q9Y4P1,O43464,Q96FW1,P28072,O95630,Q8TCT8,Q9NZ08,O14773,P55786,O75976,Q16740,O75844,Q7Z2K6 | Functions | Protein Atlas Molecular function | protein_atlas_molecular_function | 7,15,16,283,39,179,53,312,183,307,331,208,338,89,92,221,104,360,113,123,255 | 2202,2807,221,307,2205,1896,123,360,2207,338,1770,1641,179,3036,2284,1965,208,283,2623,2451,1651,1970,2679,7,53,2938,3071,3149,2978,681,1386,883,3122,1388,104,523,312,3465,1264,2635,568,2407,2112,113,1530,854,2118,3130,2829,3311,255,2473,1860,1003,89,787,3194,1485,1941,2874,2369,2644,331,2063,1486,1738,557,930,2372,3241,513,1013,414,15,2374,1743,2258,16,1020,3180,3314,3348,92,1235,39,3363,1240,1135,183,873,672 | -0.2783976197724557,-0.6058872085760314,1.3329848954478216,1.0393185235252296,-0.2783976197724557,-0.135372349749194,1.900117577201474,0.9223787132780272,-0.2783976197724557,0.9694321064173009,-0.0791229327418185,-0.023406543396603797,1.5706040688271496,-0.7925442764842194,-0.30742542710923365,-0.1637002148171849,1.3769014390666614,1.1083901252715689,-0.48467366246800686,-0.3953802206575081,-0.023406543396603797,-0.1637002148171849,-0.5147428618246798,4.93319079393823,2.8944454237079458,-0.6984719430678344,-0.8242407976278554,-0.9203741657960346,-0.7296617004136831,0.5065492848540103,0.08646767296946187,0.35250503124233246,-0.8881537960438193,0.08646767296946187,2.1742112312199944,0.6813299364803377,1.0393185235252296,-4.2831543247856265,0.14064504133157937,-0.48467366246800686,0.6070563074848513,-0.36591524642575174,-0.22076897182307467,2.01913202361103,0.03178702145824545,0.37846003298308656,-0.22076897182307467,-0.8881537960438193,-0.6058872085760314,-1.2870481640073945,1.1992511003937982,-0.3953802206575081,-0.10718036336826706,0.2739473838070137,2.3810740774224746,0.43002989007773285,-0.9853526277263864,0.05919085303596074,-0.135372349749194,-0.6365864594340644,-0.3365974794064053,-0.48467366246800686,0.992819324362481,-0.19216530124130277,0.05919085303596074,-0.05119875428749204,0.6319180709039718,0.32643528456534326,-0.3365974794064053,-1.084195613202823,0.7058818007064585,0.2739473838070137,0.8271346805755291,4.362495893754808,-0.3365974794064053,-0.05119875428749204,-0.2783976197724557,4.173401607815876,0.2739473838070137,-0.9527730995631476,-1.2870481640073945,-1.3911828140592644,2.3625615365785997,0.16754792955183684,3.176140028658313,-1.461654240448277,0.16754792955183684,0.22098784106991715,1.5493907225373234,0.37846003298308656,0.5318368798696025 | 3,477 |
Steroid metabolism | 10 | 28 | 2.546364 | 0.010885 | Q14739,Q15125,O76062,Q9UBM7,P04035,Q15392,Q15800,O15118,P04062,Q16850 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 224,100,69,205,235,170,314,85,125,95 | 85,771,519,69,913,2030,235,125,1510,3088,3271,326,1656,722,2104,2737,3330,224,100,3222,170,1465,314,95,2427,205,1130,870 | 2.3995294646169643,0.43002989007773285,0.6813299364803377,2.5631141361485468,0.32643528456534326,-0.19216530124130277,1.2664947720455977,1.8800487114656554,0.03178702145824545,-0.8561099941928391,-1.1847405024855464,0.992819324362481,-0.023406543396603797,0.48115289640719744,-0.22076897182307467,-0.5449670887544821,-1.3562641561568651,1.3329848954478216,2.250265534513931,-1.0510617648762144,1.6337937661071684,0.05919085303596074,1.0393185235252296,2.30667735249979,-0.36591524642575174,1.4204955543112385,0.22098784106991715,0.37846003298308656 | 3,477 |
Autophagy of mitochondrion | 10 | 34 | 2.541812 | 0.011028 | P21796,Q9UII2,Q7Z3C6,P27544,Q9Y3D6,O00165,P04062,Q9Y4P1,O43464,P30536 | Processes and pathways | GO Biological process | msigdb_gobp | 33,335,364,78,177,49,125,183,307,61 | 49,985,307,2662,125,3064,1086,880,2777,33,78,61,2218,2396,1710,1520,2515,726,2174,1855,728,364,2358,1110,3241,413,1543,3104,3181,1235,335,177,183,2770 | 2.961925562747231,0.2739473838070137,1.0393185235252296,-0.5147428618246798,1.8800487114656554,-0.8242407976278554,0.22098784106991715,0.35250503124233246,-0.575347982490337,3.42971985718421,2.4909615357157167,2.7397803638415104,-0.2783976197724557,-0.36591524642575174,-0.05119875428749204,0.03178702145824545,-0.42499391779294676,0.48115289640719744,-0.24951260990209947,-0.10718036336826706,0.48115289640719744,0.9223787132780272,-0.3365974794064053,0.22098784106991715,-1.084195613202823,0.8271346805755291,0.03178702145824545,-0.8561099941928391,-0.9527730995631476,0.16754792955183684,0.992819324362481,1.591741995868226,1.5493907225373234,-0.5449670887544821 | 3,477 |
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