term
stringlengths
2
121
overlap
int64
6
281
setsize
int64
7
499
score
float64
1.96
10.6
pval
float64
0
0.05
edge
stringlengths
41
1.97k
type
stringclasses
5 values
subtype
stringclasses
24 values
subtype_key
stringclasses
24 values
edge_idxs
stringlengths
11
1.17k
ann_idxs
stringlengths
19
2.31k
ann_vals
stringlengths
124
9.94k
sig_size
int64
2.2k
3.73k
Skin ulcer
10
34
2.953262
0.003144
O75874,O15269,P48735,O15270,P01889,Q03519,Q8IZA0,Q03518,Q14739,P04062
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
1,286,10,295,369,215,93,218,222,30
286,295,398,926,1776,3007,1,2743,1414,369,1534,30,2526,3340,2111,2778,10,1120,2623,2862,1450,218,215,741,2364,2045,1671,222,1821,2725,93,1046,2370,2472
1.3894476706931538,1.3636206339195902,1.1117439633053623,0.3841256925736641,-0.12517084870498654,-0.9510285615071858,3.92901774642917,-0.7116898323792509,0.06148252180205109,1.179204988513675,-0.005591913085313469,3.0603364192521147,-0.5395748804972572,-1.725900749051077,-0.2832385860448953,-0.7311921139115007,3.454011...
3,430
Exercise intolerance
6
32
2.928131
0.00341
P23786,P03886,Q9H2D1,Q9Y2R0,P12235,P00403
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
33,73,49,19,213,28
1951,28,3330,73,2819,2548,213,237,1475,33,2355,2576,1747,2990,948,2510,742,951,2197,920,2338,937,1325,49,816,1346,1350,1599,19,2024,1698,1601
-0.2123673195994045,3.0698107589013315,-1.6780491319681583,2.4178172840822203,-0.7704316844994457,-0.558403728184664,1.641034754600386,1.554325783520826,0.02805701137235168,3.0318170762153325,-0.40974773902190176,-0.5773048800496771,-0.10791253841717666,-0.9306276139125141,0.36847097049977656,-0.5208177336190014,0.5833...
3,430
Tetratricopeptide-like helical domain superfamily [IPR011990]
22
94
2.927963
0.003412
Q9UBV2,O15460,Q13042,Q8IYR2,Q6P2P2,Q9Y262,Q32P28,P13674,P49321,A0AVF1,Q9H7B4,Q6DKK2,Q13535,O75718,Q92791,P42345,Q96DB5,Q9Y6X3,O76024,Q6ZXV5,O00411,O75153
Sequence
InterPro Superfamily
interpro_homologous_superfamily
397,398,399,404,277,154,34,314,317,327,209,82,338,89,219,353,484,230,477,233,249,127
327,2173,868,249,1773,2767,398,2175,1809,1072,127,89,477,2069,1098,1533,2696,314,1030,2074,1416,353,1395,317,862,2079,2929,2553,2042,1783,1577,1967,2839,2087,1061,399,1335,2233,2722,338,2840,1788,1718,1618,2465,1858,3016,34,1036,82,277,2096,1491,480,233,2442,1586,995,404,2012,219,2566,1685,484,701,1044,2308,1658,2810,3...
1.2722190787348595,-0.31905629408571334,0.43080383738421585,1.5041368739934033,-0.12517084870498654,-0.7311921139115007,1.1117439633053623,-0.31905629408571334,-0.1424888753229872,0.2735187641595761,2.0547236877093185,2.2994483251380298,0.9321647887240839,-0.26542599868242417,0.25751962221115077,-0.005591913085313469,-...
3,430
Lipid transporter activity
13
23
2.927119
0.003421
P08183,P30536,Q4KMQ2,P17900,O14678,Q9BZF1,P61916,O14975,Q96SU4,O15118,Q14849,P22059,Q96GC9
Functions
GO Molecular function
msigdb_gomf
159,2,163,66,257,458,512,424,564,109,27,316,188
2796,257,424,109,159,676,66,316,555,2,1914,512,2648,27,163,2193,730,188,564,1591,1553,458,3380
-0.7507725016906376,1.4661818634308703,1.04340337414266,2.1784605959005607,1.8695432160167267,0.6431811538013191,2.4918352621956807,1.2984956621256847,0.7896879996375533,3.92901774642917,-0.1948058268211105,0.8756421363992508,-0.6344483133432426,3.0792691433168833,1.8577557582221775,-0.31905629408571334,0.5984052493734...
3,430
secondary carrier transporter
12
15
2.915082
0.003556
O75746,P55011,Q96ES6,O14975,Q9UBX3,Q9UJS0,Q9BXP2,O95202,Q8TB61,Q9Y6M7,Q9BQT8,Q15043
Functions
Panther Protein class
panther_protein_class
692,574,37,424,13,708,601,401,55,548,157,191
424,692,401,574,696,191,2193,55,37,157,601,1409,13,708,548
1.04340337414266,0.6282990804246098,1.0981470112960925,0.7607169539788241,0.6282990804246098,1.750489731196436,-0.31905629408571334,2.606176282501621,3.0222783212407616,1.8813049364421908,0.7315827923762055,0.07811250742307049,3.391761695054266,0.6282990804246098,0.8184979173823138
3,430
Abnormal joint morphology
57
288
2.914723
0.00356
Q7LGA3,P38435,P10321,O15460,P51571,P06280,O95202,Q6DKJ4,Q15392,P21964,P08236,P04062,Q86XL3,O75844,P23786,P49902,O15269,O95831,P07602,P37268,Q99567,P16278,O15270,Q9Y619,Q9Y487,P50402,Q15427,Q9Y4P3,Q9NZ08,Q14108,Q15043,P42858,Q6NUQ1,P42892,Q9NZJ7,Q9UL01,Q96L58,Q13535,Q96PU5,O96028,O75718,Q8IZA0,Q14739,Q96AY3,Q96RL7,P1643...
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
128,136,393,398,403,275,401,406,23,280,279,30,161,32,33,160,286,414,38,166,42,43,295,45,175,431,312,313,185,60,191,447,452,69,341,79,339,338,211,334,89,93,222,357,358,231,360,233,369,118,119,380,379,250,123,376,254
2173,1472,2026,3401,1389,1437,2107,977,2816,1438,1738,286,295,3322,454,398,2174,3060,2350,837,2283,2217,376,605,2143,1776,2594,2410,1356,2284,2574,1010,566,89,3248,32,2070,2947,1777,2179,401,2223,927,2502,3286,414,3151,334,2618,369,1534,858,30,1877,275,3232,2819,1254,3082,38,279,2548,393,1189,1255,1256,3046,3340,1223,1...
-0.31905629408571334,0.02805701137235168,-0.24767692023999524,-2.397311077076706,0.07811250742307049,0.04479749007284595,-0.2832385860448953,0.33701658189477507,-0.7704316844994457,0.04479749007284595,-0.10791253841717666,1.3894476706931538,1.3636206339195902,-1.6306790060749776,0.9741576934609325,1.1117439633053623,-0...
3,430
Elevated pulmonary artery pressure
13
26
2.906197
0.003659
O75844,Q6NUK1,P51970,O14678,O96000,P03886,P51798,P14854,P01889,Q8IZA0,Q14108,P00403,P04062
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
32,580,386,257,606,73,524,363,369,93,60,28,30
257,2145,32,606,28,369,1534,73,30,1255,363,1119,3127,2073,2925,2000,524,386,60,680,2676,580,93,1624,2132,3043
1.4661818634308703,-0.30111518243997987,3.050846065270086,0.7169539114401163,3.0698107589013315,1.179204988513675,-0.005591913085313469,2.4178172840822203,3.0603364192521147,0.1604504658814682,1.1925938145223307,0.24146991514915547,-1.096295452188383,-0.26542599868242417,-0.8699343008139493,-0.22999085661134913,0.86141...
3,430
Sphingolipid pathway
6
8
2.906129
0.003659
Q06136,O15269,O95470,Q13510,Q96G23,P04062
Processes and pathways
WikiPathways
msigdb_wp
258,286,86,250,124,30
286,295,86,30,1751,258,250,124
1.3894476706931538,1.3636206339195902,2.321161071650228,3.0603364192521147,-0.10791253841717666,1.4661818634308703,1.5041368739934033,2.066089721766653
3,430
Endopeptidase activity
17
65
2.90216
0.003706
Q8TCT9,Q99797,O14773,O75844,Q10713,Q2T9J0,O43292,P42892,P28072,P67812,P49721,Q4J6C6,Q5JRX3,Q6P179,Q9NZ08,Q9BYT8,Q96K76
Functions
GO Molecular function
msigdb_gomf
289,290,162,32,292,320,194,69,199,173,142,371,85,407,185,349,255
162,194,800,1532,32,3215,3082,2857,2148,3257,437,984,3164,2287,199,1881,2227,2641,804,1710,820,69,2150,1448,2460,142,1417,2700,3318,1613,1642,173,292,1857,2048,637,2751,1517,320,371,85,2368,597,407,901,1861,1020,289,612,1083,1684,1834,1269,255,2310,1303,2098,290,2887,349,185,1093,1095,2452,1025
1.8577557582221775,1.738437938975464,0.4923857069491886,-0.005591913085313469,3.050846065270086,-1.267862233870033,-1.0335027512907717,-0.8099892376198776,-0.30111518243997987,-1.3782981393570042,1.0158151806848401,0.33701658189477507,-1.1599171531024435,-0.373271876429598,1.7263589960332117,-0.1773059016141884,-0.3370...
3,430
Subcutaneous nodule
6
17
2.889368
0.00386
O75874,P48735,P35637,P06280,Q9NZ08,Q13510
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
1,10,235,275,185,250
1,369,858,275,1535,693,1190,235,10,796,1120,1450,2556,250,1903,185,1470
3.92901774642917,1.179204988513675,0.44626893355334946,1.4151493408700357,-0.005591913085313469,0.6282990804246098,0.19301386899346543,1.5667994320520733,3.454011813127605,0.5076661391022604,0.24146991514915547,0.04479749007284595,-0.558403728184664,1.5041368739934033,-0.1773059016141884,1.774512395985724,0.04479749007...
3,430
Lipid metabolism
53
135
2.889189
0.003862
Q06136,O76062,Q53GQ0,P61916,Q9NP80,O14734,O00767,Q06520,Q8NCG7,Q15392,Q96K12,O15254,P04062,P23786,O15269,Q8N2A8,P07602,P37268,Q9P035,O14975,O15270,O95864,Q8NHP8,A1L0T0,O75477,Q96N66,Q15067,P17900,Q709F0,P54646,Q9NWU1,Q99519,Q16850,O75845,O95470,Q9H7Z7,Q15800,Q8NCC3,Q9NPH0,Q14739,Q9UG56,P48651,Q13510,Q9NUQ2,P51648,Q9UBM...
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
258,382,262,512,264,391,644,144,534,23,283,285,30,33,286,164,38,166,294,424,295,554,53,54,566,189,319,66,457,75,590,340,210,470,86,474,88,91,94,222,487,360,250,367,110,632,109,501,506,625,252,124,641
54,1184,2986,3427,644,391,424,109,285,286,295,1161,566,2694,470,382,2070,3323,86,1144,554,1876,30,3421,38,3287,2480,3358,3415,2697,1444,66,2504,1997,33,2354,2434,501,3344,3011,1318,928,252,166,2078,2183,948,740,929,2776,1884,2802,753,360,796,1258,1058,1364,110,1194,1855,3383,1013,75,2510,2081,512,2837,2607,3312,258,144...
2.6267135515683826,0.19301386899346543,-0.9306276139125141,-4.650483787176411,0.6728169776242082,1.125305736257329,1.04340337414266,2.1784605959005607,1.3894476706931538,1.3894476706931538,1.3636206339195902,0.20921739577808898,0.7752227411673067,-0.6729168790091554,0.9462000577616902,1.1523245386286525,-0.265425998682...
3,430
Serine hydrolase activity
10
18
2.886771
0.003892
Q2T9J0,O14773,P10619,Q9HB40,Q9H3G5,P67812,P42785,Q4J6C6,Q5JRX3,O75976
Functions
GO Molecular function
msigdb_gomf
320,162,226,40,331,173,207,371,85,567
162,567,226,2857,2227,804,207,1448,1033,173,1517,320,371,85,597,1064,331,40
1.8577557582221775,0.7752227411673067,1.6040461907838122,-0.8099892376198776,-0.33706243340680064,0.4923857069491886,1.6777690135569574,0.04479749007284595,0.30536674022651894,1.8222377186127818,0.01126068031324202,1.2984956621256847,1.179204988513675,2.3319852246797077,0.7315827923762055,0.2894676887918951,1.272219078...
3,430
Dysmetria
13
58
2.884374
0.003922
O43292,O14773,Q10713,Q9NPL8,Q9NP80,Q6P4A7,Q06787,O75503,Q99519,Q6DKK2,Q5JRX3,Q9Y4P3,Q8IV08
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
194,162,292,325,264,232,203,104,340,82,85,313,120
2346,162,1438,794,194,2350,375,763,1532,104,3082,1569,1446,2073,1478,2775,1074,1961,2361,1713,2879,203,292,2045,550,3071,1582,2299,85,2842,82,2786,232,1235,120,933,1493,1494,1685,582,1001,1303,340,1212,2018,3188,264,325,2101,2102,1529,975,866,3097,1436,313,1025,2741
-0.40974773902190176,1.8577557582221775,0.04479749007284595,0.5076661391022604,1.738437938975464,-0.40974773902190176,1.1657819605638418,0.5532361269354006,-0.005591913085313469,2.189571052524327,-1.0335027512907717,-0.02250118346835699,0.04479749007284595,-0.26542599868242417,0.02805701137235168,-0.7311921139115007,0....
3,430
Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps
7
18
2.884131
0.003925
O43852,O76024,Q9BTY2,P14625,P05067,Q02818,Q07065
Processes and pathways
Reactome Pathways
msigdb_reactome
321,477,202,300,205,246,253
321,477,205,1284,1953,1255,1536,300,2619,246,253,503,1335,2236,1373,1375,1621,202
1.2853737321434007,0.9321647887240839,1.6777690135569574,0.14408985151272588,-0.2123673195994045,0.1604504658814682,-0.005591913085313469,1.3506596827179598,-0.6153265492951593,1.5167285531774126,1.4915153034770001,0.8898304908049921,0.11120892157867891,-0.33706243340680064,0.09468784334280253,0.09468784334280253,-0.03...
3,430
Proton transmembrane transporter activity
13
35
2.881325
0.00396
Q96ES6,P24539,P08574,Q9UDW1,Q9Y487,O75964,P14854,Q13423,P13073,Q00325,P12235,Q93050,P00403
Functions
GO Molecular function
msigdb_gomf
37,138,296,74,175,47,363,146,336,214,213,220,28
3081,47,401,28,736,674,296,840,213,336,363,1119,3191,3343,138,2925,784,1257,2149,2748,1075,3379,2080,726,1259,214,146,525,220,37,1409,74,2136,175,2067
-1.0335027512907717,2.748363067010926,1.0981470112960925,3.0698107589013315,0.5833929390939195,0.6431811538013191,1.3636206339195902,0.4616874064468927,1.641034754600386,1.2590315225380515,1.1925938145223307,0.24146991514915547,-1.2028041638743916,-1.7500104946959263,1.9744867066455778,-0.8699343008139493,0.52290115715...
3,430
Establishment of protein localization to organelle
45
186
2.878716
0.003993
Q99623,P30536,P46379,P52789,Q8TB36,Q9NS69,P11279,O60830,Q9Y512,Q5SRE5,Q9UGP8,P35658,Q9P0J0,O95831,Q99797,Q10713,O14737,Q7Z3B4,Q99567,O43681,Q15070,Q9Y5J7,Q14108,O43615,Q9Y5J9,O60684,P55786,O15397,O14925,Q99595,Q92973,Q5JRX3,Q99523,Q8N1F7,Q9Y2T2,Q8N4H5,Q96RL7,P46934,Q9HD47,Q9Y5M8,P13473,Q15629,P52294,Q9Y584,Q9Y5L4
Processes and pathways
GO Biological process
msigdb_gobp
517,2,256,510,390,7,646,20,278,662,547,657,158,414,290,292,165,559,42,553,181,571,60,565,193,198,575,328,204,78,208,85,600,611,617,101,358,103,106,236,237,116,117,119,125
2173,2026,1248,1437,1908,1116,2347,165,2348,204,907,328,565,553,1809,198,20,1776,2410,2284,1056,1532,979,2069,1098,2322,1251,2898,803,3286,414,1443,1534,1877,1608,656,1285,1508,2965,3180,2108,982,646,1706,237,1538,2858,1880,2260,1147,3127,2073,2505,2,1999,3218,657,2642,1572,3145,2111,739,256,103,2778,677,2151,2184,1915...
-0.31905629408571334,-0.24767692023999524,0.1604504658814682,0.04479749007284595,-0.1948058268211105,0.24146991514915547,-0.40974773902190176,1.8459424393187207,-0.40974773902190176,1.6777690135569574,0.3997325317718629,1.2722190787348595,0.7752227411673067,0.7896879996375533,-0.1424888753229872,1.7263589960332117,3.21...
3,430
Molecular transducer activity
11
34
2.877562
0.004008
P30536,O15173,O14786,Q8WTV0,Q9BUN8,O15118,Q15629,Q9Y6I9,Q99720,Q14108,Q9UGP8
Functions
GO Molecular function
msigdb_gomf
2,99,520,169,366,109,116,572,26,60,547
520,945,109,99,1607,1221,873,1509,1147,2,2111,3289,796,2904,2364,1578,60,116,950,1674,2754,169,1656,882,793,600,26,366,1245,2497,2343,547,1279,572
0.861414936766202,0.36847097049977656,2.1784605959005607,2.211724229893288,-0.03946755021715677,0.17675834803240076,0.43080383738421585,0.01126068031324202,0.22536929144369766,3.92901774642917,-0.2832385860448953,-1.4913543909405875,0.5076661391022604,-0.8498704751461239,-0.40974773902190176,-0.02250118346835699,2.5336...
3,430
Mitochondrial calcium ion transport
6
15
2.875381
0.004035
Q10713,P21796,P45880,Q9Y277,O95202,Q8IYU8
Processes and pathways
Reactome Pathways
msigdb_reactome
292,9,15,309,401,347
1532,401,9,1781,15,292,347,1130,1236,1324,1303,517,1530,309,1025
-0.005591913085313469,1.0981470112960925,3.489279818123242,-0.12517084870498654,3.2925394092933984,1.3765499068522848,1.2458108826688405,0.24146991514915547,0.17675834803240076,0.1276761298241045,0.14408985151272588,0.8756421363992508,0.01126068031324202,1.3376668826640072,0.32121625895525563
3,430
Abnormal retinal vascular morphology
13
51
2.874716
0.004044
P17900,P10619,P07602,P38435,P03886,P16278,Q9NZJ7,Q99519,P06865,P04439,Q9Y4P3,Q13510,P21964
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
66,226,38,136,73,43,341,340,268,244,313,250,280
2406,1472,1328,1439,2350,961,1874,413,1638,2818,1533,3045,73,244,268,38,1358,3189,226,2856,2878,43,66,2073,693,280,1747,1190,2775,3068,2357,136,2801,1543,2991,2670,2879,696,250,2299,1374,744,2057,1131,2422,1156,792,340,341,866,313
-0.4464943548499513,0.02805701137235168,0.11120892157867891,0.04479749007284595,-0.40974773902190176,0.3527680424371989,-0.1773059016141884,1.07084676596474,-0.0564914375226667,-0.7704316844994457,-0.005591913085313469,-0.992089953515064,2.4178172840822203,1.5292904957224467,1.4279535786684734,3.0127233121243298,0.0946...
3,430
Hypertrophic cardiomyopathy
28
116
2.871433
0.004086
Q9H061,Q96CU9,Q13423,P06280,O43676,P00403,Q9P0J0,O75306,Q99797,P53701,Q86Y39,P16278,P50402,Q9Y4P3,P10253,Q9NVI7,Q9Y6M9,Q9NPL8,P03886,O15360,P15586,P54802,P12235,Q00325,P13473,P14854,P01889,O60313
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
12,274,146,275,21,28,158,413,290,167,168,43,431,313,311,443,326,325,73,454,206,87,213,214,237,363,369,375
2173,892,1950,454,21,2922,2350,1142,375,1441,413,978,1442,3248,1390,2033,3286,606,28,369,1534,73,858,275,1566,2035,723,1117,1568,311,213,237,363,206,43,3010,3029,2639,2073,693,3031,3011,1747,1478,2775,2413,2078,2748,948,1395,2507,1075,1258,3152,431,1058,2483,167,87,1290,3360,2992,2879,1034,2484,214,2934,2556,146,1670,3...
-0.31905629408571334,0.41529180787632924,-0.2123673195994045,0.9741576934609325,3.200802504118346,-0.8699343008139493,-0.40974773902190176,0.22536929144369766,1.1657819605638418,0.04479749007284595,1.07084676596474,0.33701658189477507,0.04479749007284595,-1.3560056220962575,0.07811250742307049,-0.24767692023999524,-1.4...
3,430
Abnormal bone structure
42
188
2.86753
0.004137
O75874,P61978,P38435,P48735,P06280,O95202,Q15392,P08236,P04062,Q86XL3,O75844,O95831,Q32P28,P07602,P16278,Q13277,Q9Y619,Q9Y487,Q9NWM8,O15228,Q9Y4P3,P42695,Q14108,Q15043,O43292,O15360,Q9NZJ7,Q99519,Q96L58,O75845,O96028,P54802,P12235,O75718,P22626,Q14739,Q96AY3,P48651,Q13126,Q96HY6,Q13510,O60568
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
1,387,136,10,275,401,23,279,30,161,32,414,34,38,43,427,45,175,179,307,313,439,60,191,194,454,341,340,339,470,334,87,213,89,343,222,357,360,113,380,250,376
1184,2173,2107,977,3418,1438,869,2407,307,3322,454,2174,194,3060,2176,539,2987,2350,837,1097,376,1776,2574,1056,1010,2145,89,32,470,1,2897,2179,401,1414,2502,414,3151,334,1534,30,1877,3421,1606,2949,275,3232,1566,2526,1284,38,279,981,1189,213,3340,3412,43,3010,2109,3303,896,1415,3127,2073,693,343,3163,3328,2772,738,897...
0.19301386899346543,-0.31905629408571334,-0.2832385860448953,0.33701658189477507,-3.637988436906538,0.04479749007284595,0.43080383738421585,-0.4464943548499513,1.3376668826640072,-1.6306790060749776,0.9741576934609325,-0.31905629408571334,1.738437938975464,-1.0127520150653435,-0.31905629408571334,0.8184979173823138,-0....
3,430
Anion transmembrane transport
12
40
3.751424
0.000176
Q9BQT8,P21796,Q9UBX3,Q9Y619,P45880,P30825,Q14728,Q8TB61,Q02978,Q9H2D1,P08183,Q9UHG3
Processes and pathways
GO Biological process
msigdb_gobp
0,129,133,176,107,47,116,53,24,188,29,163
628,3080,2043,2471,674,1737,1874,29,2859,474,840,129,47,107,966,1573,198,1142,1515,24,853,116,2004,2497,1359,857,53,1218,0,598,188,1119,2024,133,163,1381,1234,3104,176,763
0.5250999447143083,-0.8742752381374652,-0.2645994293667072,-0.4618996447455134,0.47495811622353734,-0.1269547709677774,-0.1816960246922895,3.5620249416133856,-0.6649598650903187,0.7224951214644277,0.3481518092503356,1.9639610723159058,3.052160204819215,2.232989840713281,0.2710412960006848,-0.04561234257665679,1.4446118...
3,430
Protein localization to mitochondrion
23
59
3.660499
0.000252
Q99797,O43615,O95831,P55786,Q15070,Q9P0J0,Q9Y512,Q5JRX3,Q9Y6C9,Q9BZL1,Q99595,Q9Y5L4,Q9NS69,O14737,Q10713,O60830,P30419,P30536,Q9Y584,Q9Y5J9,Q3ZCQ8,Q8N4H5,Q9Y5J7
Processes and pathways
GO Biological process
msigdb_gobp
263,10,17,18,274,153,154,30,177,441,184,57,65,72,467,82,210,90,230,99,353,367,390
1127,2096,1494,72,461,10,82,1989,1924,2853,1871,3163,17,2897,1669,633,3271,2860,1931,1932,210,90,1881,2904,590,2650,2426,1141,18,1513,851,467,274,820,3190,353,1696,30,895,367,554,1266,2986,184,263,441,2625,65,153,3238,2150,2153,3409,154,230,390,99,57,177
0.16698324905786777,-0.2924495622566737,-0.018699141472303806,2.65148526846722,0.7468240195253295,4.430040959592227,2.454560157968432,-0.23685790765018927,-0.20922382367890077,-0.6649598650903187,-0.1816960246922895,-0.9660347186392164,4.298513011896481,-0.6944666864709049,-0.09973910959887115,0.5250999447143083,-1.185...
3,430
Organic acid transmembrane transport
9
29
3.55942
0.000372
Q9BQT8,O43772,Q9UBX3,Q9Y619,P30825,Q02978,P23786,Q9H2D1,P08183
Processes and pathways
GO Biological process
msigdb_gobp
0,35,133,176,47,24,89,188,29
527,35,3080,2043,2471,674,1874,29,2859,294,89,1043,47,2110,1249,1573,198,24,2004,2497,857,1218,0,188,1119,2024,133,1381,176
0.6490544769648282,3.3829136623223524,-0.8742752381374652,-0.2645994293667072,-0.4618996447455134,0.47495811622353734,-0.1816960246922895,3.5620249416133856,-0.6649598650903187,1.0798749037476432,2.374606434529858,0.2191928482299109,3.052160204819215,-0.2924495622566737,0.11440539204641399,-0.04561234257665679,1.444611...
3,430
SLC superfamily of solute carriers
12
41
3.4681
0.000524
Q9BQT8,O43772,Q9UBX3,Q9Y6C9,Q9Y619,P30825,Q70HW3,Q9BSK2,Q8TB61,Q8IXU6,Q02978,Q9H2D1
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
0,35,133,177,176,47,19,21,53,85,24,188
488,35,628,2043,1870,674,1737,2859,294,474,840,47,1573,198,1142,1515,24,479,2497,3411,1901,3129,19,85,53,1218,2080,0,21,598,2199,188,560,1119,2024,625,133,1381,176,177,763
0.6980910015238436,3.3829136623223524,0.5250999447143083,-0.2645994293667072,-0.1816960246922895,0.47495811622353734,-0.1269547709677774,-0.6649598650903187,1.0798749037476432,0.7224951214644277,0.3481518092503356,3.052160204819215,-0.04561234257665679,1.4446118836303585,0.16698324905786777,-0.018699141472303806,3.8766...
3,430
Endopeptidase activity
24
65
3.443274
0.000575
P28074,Q99797,Q96K76,Q9Y4E8,Q9UPU5,O75844,P49721,Q5JRX3,P42574,P67812,P60900,Q6P179,P48147,O43847,P28070,O43292,P42892,Q10713,Q2T9J0,P20618,Q9NZ08,Q99436,P28072,P22695
Functions
GO Molecular function
msigdb_gomf
130,263,400,279,278,150,27,30,423,44,296,436,186,312,66,446,80,467,481,234,372,370,245,123
1726,446,312,1989,150,2587,3109,2861,1991,3062,234,123,1810,66,245,130,2052,2762,1138,1406,423,80,2593,186,547,27,1095,1752,2533,1460,296,44,467,1632,2545,496,1896,1259,481,1011,30,2605,1476,436,790,942,617,687,2255,1062,2016,901,1023,400,1485,1785,370,263,3304,831,372,278,279,2463,954
-0.1269547709677774,0.7710783389724302,1.0331289835246766,-0.23685790765018927,1.686517510151732,-0.5193086864663775,-0.9047202020189336,-0.6649598650903187,-0.23685790765018927,-0.8439693958817623,1.2642420204413092,2.0267654021496413,-0.1542733780946316,2.786918603681663,1.2185345905694018,1.9429272467743128,-0.26459...
3,430
Mitochondrial respiratory chain complex assembly
14
39
3.386248
0.000709
Q6DKK2,Q7L592,Q69YU5,P51970,Q96CU9,P03886,O95831,Q86Y39,Q15070,Q9BSK2,O43676,Q9P0J0,Q9Y512,Q9H061
Processes and pathways
GO Biological process
msigdb_gobp
121,298,69,197,76,48,17,145,274,21,52,153,154,25
1172,52,3139,2468,1731,673,2412,1868,1082,657,2103,17,807,48,2711,407,197,2774,274,2666,1636,69,121,298,145,2072,1061,76,21,1845,25,1118,3296,540,153,2153,318,154,922
0.14074080589325716,2.977118417761843,-0.9353060839224018,-0.4618996447455134,-0.1269547709677774,0.47495811622353734,-0.43337197786310955,-0.1816960246922895,0.1931336313940024,0.5000697536260212,-0.2924495622566737,4.298513011896481,0.3736820608268665,3.0334540690374134,-0.5771985292104522,0.8434001246148884,1.444611...
3,430
Mitochondrial transmembrane transport
12
51
3.358594
0.000783
Q9BQT8,P21796,O43772,O43615,Q9Y619,O95831,O60830,Q9BSK2,Q99595,P23786,Q9H2D1,O75964
Processes and pathways
GO Biological process
msigdb_gobp
0,129,35,10,176,17,82,21,184,89,188,92
461,10,35,82,1867,1989,2043,3222,92,1924,1870,674,17,2897,1737,1294,3271,474,840,129,89,677,3242,3000,3350,1249,1573,2769,2175,1515,820,3170,353,684,213,3293,2834,1266,1218,184,0,21,188,1119,2024,2625,1656,1381,952,954,176
0.7468240195253295,4.430040959592227,3.3829136623223524,2.454560157968432,-0.1816960246922895,-0.23685790765018927,-0.2645994293667072,-1.0590960879944016,2.3545091190795486,-0.20922382367890077,-0.1816960246922895,0.47495811622353734,4.298513011896481,-0.6944666864709049,-0.1269547709677774,0.08797608280824076,-1.1852...
3,430
Organic anion transmembrane transporter activity
9
28
3.325201
0.000884
Q9BQT8,P53985,Q9UBX3,Q9Y619,P30825,Q14728,Q8TB61,Q02978,Q9H2D1
Functions
GO Molecular function
msigdb_gomf
0,198,133,176,47,116,53,24,188
628,2043,674,1737,2859,294,474,840,47,1573,198,24,116,2497,1901,3129,857,53,1218,2080,0,188,1119,2024,133,1381,176,763
0.5250999447143083,-0.2645994293667072,0.47495811622353734,-0.1269547709677774,-0.6649598650903187,1.0798749037476432,0.7224951214644277,0.3481518092503356,3.052160204819215,-0.04561234257665679,1.4446118836303585,3.876685011005403,2.1098231391580686,-0.4618996447455134,-0.1816960246922895,-0.9047202020189336,0.3481518...
3,430
SLC25 family of mitochondrial transporters
8
20
3.302835
0.000957
Q9BQT8,O43772,Q9UBX3,Q9Y6C9,Q9Y619,Q70HW3,Q9BSK2,Q02978
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
0,35,133,177,176,19,21,24
35,628,2043,1737,474,840,1573,1515,24,1901,19,0,21,188,1119,625,133,1381,176,177
3.3829136623223524,0.5250999447143083,-0.2645994293667072,-0.1269547709677774,0.7224951214644277,0.3481518092503356,-0.04561234257665679,-0.018699141472303806,3.876685011005403,-0.1816960246922895,4.0981386289037935,7.334174106783736,3.996510780247743,1.489107550065657,0.1931336313940024,0.5500494221591544,1.9218433491...
3,430
Mitochondrial carrier domain superfamily [IPR023395]
8
20
3.302835
0.000957
Q9BQT8,O43772,Q9UBX3,Q9Y6C9,Q9Y619,Q70HW3,Q9BSK2,Q02978
Sequence
InterPro Superfamily
interpro_homologous_superfamily
0,35,133,177,176,19,21,24
35,628,2043,1737,474,840,1573,1515,24,1901,19,0,21,188,1119,625,133,1381,176,177
3.3829136623223524,0.5250999447143083,-0.2645994293667072,-0.1269547709677774,0.7224951214644277,0.3481518092503356,-0.04561234257665679,-0.018699141472303806,3.876685011005403,-0.1816960246922895,4.0981386289037935,7.334174106783736,3.996510780247743,1.489107550065657,0.1931336313940024,0.5500494221591544,1.9218433491...
3,430
Mitochondrial substrate/solute carrier [IPR018108]
8
20
3.302835
0.000957
Q9BQT8,O43772,Q9UBX3,Q9Y6C9,Q9Y619,Q70HW3,Q9BSK2,Q02978
Sequence
InterPro Repeat
interpro_repeat
0,35,133,177,176,19,21,24
35,628,2043,1737,474,840,1573,1515,24,1901,19,0,21,188,1119,625,133,1381,176,177
3.3829136623223524,0.5250999447143083,-0.2645994293667072,-0.1269547709677774,0.7224951214644277,0.3481518092503356,-0.04561234257665679,-0.018699141472303806,3.876685011005403,-0.1816960246922895,4.0981386289037935,7.334174106783736,3.996510780247743,1.489107550065657,0.1931336313940024,0.5500494221591544,1.9218433491...
3,430
Organic acid transport
9
46
3.29827
0.000973
Q9BQT8,O43772,Q9UBX3,Q9Y619,P30825,Q02978,P23786,Q9H2D1,P08183
Processes and pathways
GO Biological process
msigdb_gobp
0,35,133,176,47,24,89,188,29
527,488,35,628,3080,2043,2471,674,1668,2754,1454,1874,1497,29,2859,294,708,1676,89,1043,2422,47,2110,1249,1573,198,1142,1939,1889,24,2004,1763,2497,3129,684,857,1218,0,188,1119,2024,456,133,1381,1124,176
0.6490544769648282,0.6980910015238436,3.3829136623223524,0.5250999447143083,-0.8742752381374652,-0.2645994293667072,-0.4618996447455134,0.47495811622353734,-0.09973910959887115,-0.6063272975273538,0.008115305624482679,-0.1816960246922895,-0.018699141472303806,3.5620249416133856,-0.6649598650903187,1.0798749037476432,0....
3,430
Protein insertion into membrane
13
29
3.263206
0.001102
Q9NS69,Q9Y584,Q9Y5J9,O14737,Q15070,Q15629,O43681,P30419,Q9P0J0,Q9Y512,O43765,Q9Y5L4,P46379
Processes and pathways
GO Biological process
msigdb_gobp
65,230,99,72,274,275,304,210,153,154,335,57,285
72,304,335,1924,1669,210,2904,285,2535,851,2603,274,275,1696,1473,1017,2787,1266,1267,2395,65,3154,153,2153,154,230,390,99,57
2.65148526846722,1.056535430788023,0.9625023709095525,-0.20922382367890077,-0.09973910959887115,1.3774263391294397,-0.6944666864709049,1.1031479342874442,-0.49054476129514196,0.3481518092503356,-0.5193086864663775,1.1263550473925943,1.1263550473925943,-0.09973910959887115,0.008115305624482679,0.24516178068886646,-0.606...
3,430
Organic anion transport
9
43
3.16918
0.001529
P07602,Q9BQT8,Q9UBX3,Q9Y619,P30825,Q14728,Q8TB61,Q02978,Q9H2D1
Processes and pathways
GO Biological process
msigdb_gobp
128,0,133,176,47,116,53,24,188
628,3080,2043,2471,674,1454,1737,1874,128,2859,294,474,840,708,1676,1043,47,1573,198,1142,1939,24,116,2004,1763,2497,1901,3129,857,53,1218,2080,0,188,1119,2024,456,625,133,950,1381,176,763
0.5250999447143083,-0.8742752381374652,-0.2645994293667072,-0.4618996447455134,0.47495811622353734,0.008115305624482679,-0.1269547709677774,-0.1816960246922895,1.9639610723159058,-0.6649598650903187,1.0798749037476432,0.7224951214644277,0.3481518092503356,0.4497642888546631,-0.09973910959887115,0.2191928482299109,3.052...
3,430
Anion transport
14
67
3.166765
0.001541
P07602,P21796,Q9BQT8,Q9UBX3,P30536,Q9Y619,P45880,P30825,Q14728,Q8TB61,Q02978,Q9H2D1,P08183,Q9UHG3
Processes and pathways
GO Biological process
msigdb_gobp
128,129,0,133,90,176,107,47,116,53,24,188,29,163
2515,304,628,877,3080,2043,2471,674,1454,1737,1874,128,29,2859,2808,294,474,840,708,1676,129,1043,90,47,107,966,1573,198,967,1142,1939,1515,24,853,116,2004,1763,479,2497,497,1359,3411,1901,3129,857,53,1218,1111,2080,0,598,2391,3173,188,1119,2024,456,625,133,163,950,1381,1234,3104,176,3404,763
-0.49054476129514196,1.056535430788023,0.5250999447143083,0.32253547644341873,-0.8742752381374652,-0.2645994293667072,-0.4618996447455134,0.47495811622353734,0.008115305624482679,-0.1269547709677774,-0.1816960246922895,1.9639610723159058,3.5620249416133856,-0.6649598650903187,-0.6355805774220161,1.0798749037476432,0.72...
3,430
Protein targeting to mitochondrion
20
46
3.148579
0.001641
Q99797,O43615,O95831,P55786,Q9P0J0,Q9Y512,Q5JRX3,Q9BZL1,Q99595,Q9Y5L4,Q9NS69,O14737,Q10713,O60830,P30536,Q9Y584,Q9Y5J9,Q3ZCQ8,Q8N4H5,Q9Y5J7
Processes and pathways
GO Biological process
msigdb_gobp
263,10,17,18,153,154,30,441,184,57,65,72,467,82,90,230,99,353,367,390
1127,72,461,10,82,1989,1924,2853,1871,3163,17,2897,1669,3271,1932,90,2904,590,2650,2426,18,1513,467,820,3190,353,1696,30,895,367,554,2986,184,263,441,2625,65,153,3238,2150,3409,154,230,390,99,57
0.16698324905786777,2.65148526846722,0.7468240195253295,4.430040959592227,2.454560157968432,-0.23685790765018927,-0.20922382367890077,-0.6649598650903187,-0.1816960246922895,-0.9660347186392164,4.298513011896481,-0.6944666864709049,-0.09973910959887115,-1.185294978940291,-0.20922382367890077,2.374606434529858,-0.694466...
3,430
transporter
14
56
3.146232
0.001654
O43772,Q9HD45,P53985,Q9Y584,Q9H2D1,Q567V2,O43615,Q9Y619,Q92973,O15397,Q15070,O60830,Q99595,Q9NR77
Functions
Panther Protein class
panther_protein_class
35,132,198,230,188,9,10,176,270,78,274,82,184,56
1663,2849,956,1448,1980,1287,78,10,304,35,2469,82,1732,1608,1457,1139,2236,1935,1507,2908,1936,1573,198,967,2427,968,2535,971,2825,274,9,3411,1587,723,751,2837,576,484,270,2018,1114,184,2080,3352,622,188,560,539,132,56,760,2332,952,230,3158,176
-0.09973910959887115,-0.6649598650903187,0.2710412960006848,0.008115305624482679,-0.23685790765018927,0.08797608280824076,2.474441012066322,4.430040959592227,1.056535430788023,3.3829136623223524,-0.4618996447455134,2.454560157968432,-0.1269547709677774,-0.0726253190224832,0.008115305624482679,0.16698324905786777,-0.348...
3,430
Protein localization
33
77
3.135159
0.001718
P21796,A8MXV4,O75381,O43615,Q9Y512,Q13505,Q5JRX3,P46379,P51648,P08574,P05067,O75431,O43681,Q99595,Q9NR77,Q9Y5L4,Q15067,Q9NS69,O15254,P09601,O15228,Q10713,O60830,O43765,O14925,P12235,Q9Y5J9,Q9Y584,O75874,Q2T9J0,Q3ZCQ8,Q8N4H5,Q9Y5J7
Processes and pathways
Reactome Pathways
msigdb_reactome
129,250,377,10,154,155,30,285,295,421,293,171,304,184,56,57,191,65,201,202,445,467,82,335,461,474,99,230,226,481,353,367,390
250,991,563,461,488,445,201,10,304,335,628,82,377,2753,171,1989,703,2043,226,1924,2897,293,1294,421,3320,202,3271,474,840,1991,129,2420,3242,1043,1747,2478,3299,928,285,591,2114,886,295,2173,3356,2432,467,3302,1518,155,191,820,481,353,30,1017,367,1774,554,901,184,2886,2625,56,65,2457,2329,2990,1381,1124,2153,2513,154,2...
1.1955860310511912,0.24516178068886646,0.5997091132340037,0.7468240195253295,0.6980910015238436,0.7710783389724302,1.4222760763698468,4.430040959592227,1.056535430788023,0.9625023709095525,0.5250999447143083,2.454560157968432,0.8912531522485077,-0.6063272975273538,1.555417548414023,-0.23685790765018927,0.44976428885466...
3,430
Carboxylic acid transport
7
32
3.133487
0.001727
P07602,Q9BQT8,Q9UBX3,Q9Y619,P30825,Q02978,Q9H2D1
Processes and pathways
GO Biological process
msigdb_gobp
128,0,133,176,47,24,188
3080,2043,2471,674,1454,1874,128,2859,708,1676,1043,47,1573,198,1142,1939,24,2004,1763,2497,3129,857,1218,0,188,1119,2024,456,625,133,1381,176
-0.8742752381374652,-0.2645994293667072,-0.4618996447455134,0.47495811622353734,0.008115305624482679,-0.1816960246922895,1.9639610723159058,-0.6649598650903187,0.4497642888546631,-0.09973910959887115,0.2191928482299109,3.052160204819215,-0.04561234257665679,1.4446118836303585,0.16698324905786777,-0.20922382367890077,3....
3,430
Mitochondrial protein import
18
36
3.094749
0.00197
P21796,Q9NS69,Q9Y584,Q9Y5J9,Q9Y5J7,Q3ZCQ8,O43615,P08574,O75431,Q10713,Q8N4H5,O60830,O14925,Q99595,Q9Y5L4,Q9Y512,Q13505,Q5JRX3
Processes and pathways
Reactome Pathways
msigdb_reactome
129,65,230,99,390,353,10,421,171,467,367,82,461,184,57,154,155,30
461,10,82,2753,171,1989,2043,1924,2897,1294,421,3271,474,840,129,3242,3299,886,467,155,820,353,30,367,184,2886,2625,65,2457,1381,2153,154,230,390,99,57
0.7468240195253295,4.430040959592227,2.454560157968432,-0.6063272975273538,1.555417548414023,-0.23685790765018927,-0.2645994293667072,-0.20922382367890077,-0.6944666864709049,0.08797608280824076,0.8193657703584537,-1.185294978940291,0.7224951214644277,0.3481518092503356,1.9639610723159058,-1.121886238622577,-1.24933961...
3,430
Mitochondrial transport
31
85
3.046788
0.002313
Q99797,Q9UBX3,O43615,O95831,P55786,Q15070,Q9P0J0,Q9Y512,Q5JRX3,O43772,O75431,Q9BZL1,Q8IXI1,Q99595,Q9Y5L4,Q9NS69,Q14849,O14737,Q10713,O60830,P30419,O14925,P23786,P30536,O75964,Q9Y5J9,Q9Y584,Q3ZCQ8,P45880,Q8N4H5,Q9Y5J7
Processes and pathways
GO Biological process
msigdb_gobp
263,133,10,17,18,274,153,154,30,35,171,441,310,184,57,65,71,72,467,82,210,461,89,90,92,99,230,353,107,367,390
1127,72,461,10,35,82,1130,171,1989,3222,92,1924,2853,1871,3163,17,2897,2703,1737,1294,1669,2523,3271,474,1932,89,677,3242,1934,210,90,2904,3000,2715,107,3350,2112,590,2650,1249,2426,1141,18,2769,2175,1513,851,467,71,274,820,3190,353,1696,30,1901,895,310,1158,367,554,1266,556,2620,2986,184,263,441,2625,3305,65,153,3238,...
0.16698324905786777,2.65148526846722,0.7468240195253295,4.430040959592227,3.3829136623223524,2.454560157968432,0.16698324905786777,1.555417548414023,-0.23685790765018927,-1.0590960879944016,2.3545091190795486,-0.20922382367890077,-0.6649598650903187,-0.1816960246922895,-0.9660347186392164,4.298513011896481,-0.694466686...
3,430
Mitochondrial membrane organization
14
50
3.000588
0.002695
Q9NS69,Q9Y584,Q9Y5J9,O14737,Q3ZCQ8,P45880,O75431,Q8IXI1,Q15070,P30419,Q9P0J0,Q9Y512,Q13505,Q9Y5L4
Processes and pathways
GO Biological process
msigdb_gobp
65,230,99,72,353,107,171,310,274,210,153,154,155,57
2096,72,1390,1130,171,1924,1870,2703,1737,1669,2523,633,474,1934,210,2904,3299,2715,107,2112,2650,2114,1141,851,155,274,1009,353,1696,1360,1421,1700,310,1158,1266,1029,3133,65,987,2457,153,2150,2153,954,154,230,390,99,57,2157
-0.2924495622566737,2.65148526846722,0.03483200299770884,0.16698324905786777,1.555417548414023,-0.20922382367890077,-0.1816960246922895,-0.5771985292104522,-0.1269547709677774,-0.09973910959887115,-0.49054476129514196,0.5250999447143083,0.7224951214644277,-0.20922382367890077,1.3774263391294397,-0.6944666864709049,-1.2...
3,430
Metallopeptidase activity
17
41
2.945554
0.003224
P09960,Q99797,Q9NQW7,O00303,Q969V3,Q9NZ08,P42892,Q10713,P55786,Q96DE0,P36551,O75844,Q6P179,Q9UIQ6,P22695,O43847,Q5JRX3
Functions
GO Molecular function
msigdb_gomf
403,263,402,134,233,372,80,467,18,148,306,150,436,62,123,312,30
134,2966,462,312,1989,150,770,879,2349,403,2899,1991,123,3183,306,80,848,2484,1752,18,467,30,436,789,1018,2016,233,148,2195,1785,263,3304,831,2138,1225,402,3055,372,62,914,954
1.90070904556051,-0.7538691878397593,0.7468240195253295,1.0331289835246766,-0.23685790765018927,1.686517510151732,0.399127033313968,0.32253547644341873,-0.4049604270237952,0.8434001246148884,-0.6944666864709049,-0.23685790765018927,2.0267654021496413,-0.9969079805068028,1.056535430788023,2.474441012066322,0.34815180925...
3,430
Organic acid transmembrane transporter activity
7
19
2.918364
0.003519
Q9BQT8,Q9UBX3,Q9Y619,P30825,Q02978,Q9H2D1,P08183
Functions
GO Molecular function
msigdb_gomf
0,133,176,47,24,188,29
488,2043,674,29,2859,47,1573,198,24,2497,3129,1218,0,188,1119,2024,133,1381,176
0.6980910015238436,-0.2645994293667072,0.47495811622353734,3.5620249416133856,-0.6649598650903187,3.052160204819215,-0.04561234257665679,1.4446118836303585,3.876685011005403,-0.4618996447455134,-0.9047202020189336,0.14074080589325716,7.334174106783736,1.489107550065657,0.1931336313940024,-0.23685790765018927,1.92184334...
3,430
Nadh dehydrogenase complex assembly
8
28
2.916877
0.003536
P51970,Q96CU9,P03886,Q86Y39,Q15070,O43676,Q9P0J0,Q9H061
Processes and pathways
GO Biological process
msigdb_gobp
197,76,48,145,274,52,153,25
1172,52,3139,1731,673,2412,1868,657,2103,807,48,2711,197,274,2666,1636,298,145,2072,1061,76,1845,25,1118,540,153,2153,922
0.14074080589325716,2.977118417761843,-0.9353060839224018,-0.1269547709677774,0.47495811622353734,-0.43337197786310955,-0.1816960246922895,0.5000697536260212,-0.2924495622566737,0.3736820608268665,3.0334540690374134,-0.5771985292104522,1.4446118836303585,1.1263550473925943,-0.5481928052179911,-0.0726253190224832,1.0798...
3,430
Response to acid chemical
7
26
2.890575
0.003845
P61586,Q9UQB8,P42345,Q8IWV8,Q14103,O95831,O94874
Processes and pathways
GO Biological process
msigdb_gobp
161,8,266,11,236,17,87
1920,1663,1924,87,17,2416,3062,2355,546,266,423,997,2112,1503,161,236,1309,820,2071,2675,11,3337,290,1331,8,2461
-0.20922382367890077,-0.09973910959887115,-0.20922382367890077,2.414669876898858,4.298513011896481,-0.43337197786310955,-0.8439693958817623,-0.4049604270237952,0.6244207392875576,1.1494967612733409,0.8193657703584537,0.24516178068886646,-0.2924495622566737,-0.018699141472303806,1.599340050103345,1.2642420204413092,0.08...
3,430
Metalloprotease
10
27
2.880216
0.003974
P09960,Q99797,Q9NQW7,Q9NZ08,P42892,P55786,O75844,Q9UIQ6,O43847,Q5JRX3
Functions
Protein Atlas Molecular function
protein_atlas_molecular_function
403,263,402,372,80,18,150,62,312,30
2966,312,1989,150,770,879,403,2899,1991,80,1752,18,30,436,2016,2195,1785,263,831,2138,1225,402,3055,372,62,914,954
-0.7538691878397593,1.0331289835246766,-0.23685790765018927,1.686517510151732,0.399127033313968,0.32253547644341873,0.8434001246148884,-0.6944666864709049,-0.23685790765018927,2.474441012066322,-0.1269547709677774,4.198797593874944,3.5620249416133856,0.7952587140908609,-0.23685790765018927,-0.3204095009349698,-0.126954...
3,430
Anion transmembrane transporter activity
12
43
2.863201
0.004194
Q9BQT8,P21796,P53985,Q9UBX3,Q9Y619,P11166,P45880,P30825,Q14728,Q8TB61,Q02978,Q9H2D1
Functions
GO Molecular function
msigdb_gomf
0,129,198,133,176,294,107,47,116,53,24,188
2515,304,628,2043,674,1737,2859,2808,294,474,840,129,47,107,966,1573,198,1142,24,116,479,2497,1359,3411,1901,3129,857,53,1218,1111,2080,0,598,2391,188,1119,2024,133,1381,1234,176,3404,763
-0.49054476129514196,1.056535430788023,0.5250999447143083,-0.2645994293667072,0.47495811622353734,-0.1269547709677774,-0.6649598650903187,-0.6355805774220161,1.0798749037476432,0.7224951214644277,0.3481518092503356,1.9639610723159058,3.052160204819215,2.232989840713281,0.2710412960006848,-0.04561234257665679,1.44461188...
3,430
oxidoreductase
11
43
2.842274
0.004479
Q8N4Q0,P51970,O15254,O43169,P00403,O95831,Q86Y39,O43676,Q08257,Q16134,Q15067
Functions
Panther Protein class
panther_protein_class
6,197,201,43,205,17,145,52,59,60,191
1172,2340,265,201,43,2699,52,3139,673,1556,657,2641,17,807,205,3286,1085,3205,841,2976,1741,844,2906,884,3117,197,1410,59,2292,2950,191,60,2666,1636,2299,2069,145,2193,6,3014,2262,2580,922
0.14074080589325716,-0.4049604270237952,1.1494967612733409,1.4222760763698468,3.1636500931702374,-0.5771985292104522,2.977118417761843,-0.9353060839224018,0.47495811622353734,-0.04561234257665679,0.5000697536260212,-0.5481928052179911,4.298513011896481,0.3736820608268665,1.3998810416079777,-1.2172366975016566,0.1931336...
3,430
metalloprotease
10
27
2.777856
0.005472
Q99797,Q9NZ08,P42892,P55786,Q6P179,O75844,Q9UIQ6,P22695,O43847,Q5JRX3
Functions
Panther Protein class
panther_protein_class
263,372,80,18,436,150,62,123,312,30
312,1989,150,879,2349,2899,1991,123,3183,845,80,1752,18,467,30,436,2555,2195,1785,263,831,1225,3055,372,62,914,954
1.0331289835246766,-0.23685790765018927,1.686517510151732,0.32253547644341873,-0.4049604270237952,-0.6944666864709049,-0.23685790765018927,2.0267654021496413,-0.9969079805068028,0.3481518092503356,2.474441012066322,-0.1269547709677774,4.198797593874944,0.7468240195253295,3.5620249416133856,0.7952587140908609,-0.4905447...
3,430
Sensorimotor neuropathy
7
30
2.763508
0.005718
P07602,Q8N2K0,Q15120,P00403,P03886,O95831,Q9NR77
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
128,228,108,205,48,17,56
1494,1450,1390,17,205,48,1873,1613,128,880,1878,710,964,2596,2173,1250,1754,1352,3068,108,228,1960,3364,1784,56,1165,624,625,318,954
-0.018699141472303806,0.008115305624482679,0.03483200299770884,4.298513011896481,1.3998810416079777,3.0334540690374134,-0.1816960246922895,-0.0726253190224832,1.9639610723159058,0.32253547644341873,-0.1816960246922895,0.4497642888546631,0.2710412960006848,-0.5193086864663775,-0.3204095009349698,0.11440539204641399,-0.1...
3,430
Establishment of protein localization to mitochondrial membrane
9
19
2.752113
0.005921
Q9NS69,Q9Y584,Q9Y5J9,O14737,Q15070,P30419,Q9P0J0,Q9Y512,Q9Y5L4
Processes and pathways
GO Biological process
msigdb_gobp
65,230,99,72,274,210,153,154,57
2096,72,1924,1669,633,210,2904,851,274,1696,1266,65,153,2153,154,230,390,99,57
-0.2924495622566737,2.65148526846722,-0.20922382367890077,-0.09973910959887115,0.5250999447143083,1.3774263391294397,-0.6944666864709049,0.3481518092503356,1.1263550473925943,-0.09973910959887115,0.11440539204641399,2.82526175583194,1.6648056078317892,-0.2924495622566737,1.6648056078317892,1.309699741732269,0.891253152...
3,430
Respirasome
13
45
2.741011
0.006125
P21912,Q6DKK2,P51970,Q13423,Q96CU9,P00403,P03886,Q86Y39,O43676,P14406,Q9P0J0,P22695,P14854
Localization
GO Cellular component
msigdb_gocc
253,121,197,135,76,205,48,145,52,22,153,123,124
1172,2340,265,52,3139,1731,673,1556,2412,1868,657,2641,2103,807,205,48,421,1927,1671,1673,22,124,3424,3031,2527,1500,253,123,2711,1746,845,407,3117,197,135,2666,1636,121,823,145,76,153,603,2153,922
0.14074080589325716,-0.4049604270237952,1.1494967612733409,2.977118417761843,-0.9353060839224018,-0.1269547709677774,0.47495811622353734,-0.04561234257665679,-0.43337197786310955,-0.1816960246922895,0.5000697536260212,-0.5481928052179911,-0.2924495622566737,0.3736820608268665,1.3998810416079777,3.0334540690374134,0.819...
3,430
Increased csf lactate
9
51
2.714993
0.006628
P51970,Q96CU9,P03886,O95831,Q86Y39,Q9NWS8,O43676,Q9P0J0,P14854
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
197,76,48,17,145,111,52,153,124
1172,1920,2340,52,3139,2468,1731,673,1556,1868,2103,17,807,205,48,2281,1673,124,2527,2711,1933,2712,1746,1138,2815,1885,3117,2653,197,2598,1193,1636,1474,1055,823,1156,145,2072,3363,1265,1061,2834,76,2317,2262,1845,2797,111,540,153,922
0.14074080589325716,-0.20922382367890077,-0.4049604270237952,2.977118417761843,-0.9353060839224018,-0.4618996447455134,-0.1269547709677774,0.47495811622353734,-0.04561234257665679,-0.1816960246922895,-0.2924495622566737,4.298513011896481,0.3736820608268665,1.3998810416079777,3.0334540690374134,-0.3766636832817624,-0.09...
3,430
Disproportionate short stature
9
30
2.707662
0.006776
Q32P28,P16278,Q96HY6,P42345,Q7LGA3,O75718,Q9UHX1,Q14739,Q15392
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
137,7,332,266,174,178,84,88,26
991,445,3177,837,2852,178,337,1086,7,3321,266,2053,1516,2365,1523,88,2368,26,137,2069,174,1317,2922,332,689,2629,1033,833,84,1444
0.24516178068886646,0.7710783389724302,-0.9969079805068028,0.3481518092503356,-0.6649598650903187,1.5333714580911204,0.9625023709095525,0.1931336313940024,5.04954191835968,-1.3794099034207994,1.1494967612733409,-0.2645994293667072,-0.018699141472303806,-0.4049604270237952,-0.018699141472303806,2.414669876898858,-0.4049...
3,430
Proportionate short stature
12
35
2.682016
0.007318
P21912,Q07864,Q13555,P16278,Q13535,Q96HY6,Q9Y619,Q96L58,Q14739,Q15392,P53701,Q16836
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
253,351,36,7,136,332,176,147,88,26,409,256
3177,2277,2852,2108,1086,7,2708,253,962,3298,1746,1882,1748,3299,964,531,887,409,888,351,136,36,88,26,434,256,2068,1639,2311,904,332,147,689,1326,176
-0.9969079805068028,-0.3766636832817624,-0.6649598650903187,-0.2924495622566737,0.1931336313940024,5.04954191835968,-0.5771985292104522,1.1955860310511912,0.2710412960006848,-1.2493396154375127,-0.1269547709677774,-0.1816960246922895,-0.1269547709677774,-1.2493396154375127,0.2710412960006848,0.6490544769648282,0.322535...
3,430
Increased serum pyruvate
7
35
2.678059
0.007405
Q96CU9,P03886,O95831,Q70HW3,O43676,P22695,Q5JRX3
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
76,48,17,19,52,123,30
1172,1920,52,1731,673,1556,1868,17,807,3081,48,2281,3341,2527,253,123,2711,1138,3117,2653,2914,30,19,145,2072,1061,76,650,1845,506,456,2797,540,2153,922
0.14074080589325716,-0.20922382367890077,2.977118417761843,-0.1269547709677774,0.47495811622353734,-0.04561234257665679,-0.1816960246922895,4.298513011896481,0.3736820608268665,-0.8742752381374652,3.0334540690374134,-0.3766636832817624,-1.4454744338975105,-0.49054476129514196,1.1955860310511912,2.0267654021496413,-0.57...
3,430
Toe walking
9
25
2.620152
0.008789
P07602,Q99720,Q9NP80,Q9H9S5,P35637,O95831,P50402,O43681,Q9NZJ7
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
128,1,456,525,326,17,591,304,625
304,17,2221,1612,128,1088,326,964,591,1573,888,1250,1754,1253,1942,3038,979,665,1426,1,755,525,456,625,874
1.056535430788023,4.298513011896481,-0.3484804617389532,-0.0726253190224832,1.9639610723159058,0.1931336313940024,0.9861130032940525,0.2710412960006848,0.5749189078741247,-0.04561234257665679,0.32253547644341873,0.11440539204641399,-0.1269547709677774,0.11440539204641399,-0.20922382367890077,-0.8138009161422909,0.27104...
3,430
Translocation
12
48
2.617773
0.008851
Q9NS69,Q9BTX1,Q9Y584,Q9Y5J9,Q9Y5J7,P41208,Q3ZCQ8,O43615,O60830,Q15629,Q99595,Q9Y5L4
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
65,98,230,99,390,196,353,10,82,275,184,57
1446,461,10,2638,82,377,1732,1396,1457,1139,196,1935,929,1936,968,3356,2535,1143,934,971,275,353,1155,1013,1587,723,751,665,2837,2130,1959,645,1431,1114,184,98,3295,695,2266,2574,65,2149,2088,3101,230,390,99,57
0.008115305624482679,0.7468240195253295,4.430040959592227,-0.5481928052179911,2.454560157968432,0.8912531522485077,-0.1269547709677774,0.03483200299770884,0.008115305624482679,0.16698324905786777,1.4446118836303585,-0.20922382367890077,0.29683224780454964,-0.20922382367890077,0.2710412960006848,-1.5459163719143243,-0.4...
3,430
Metalloprotease
13
38
2.601604
0.009279
Q99797,Q92922,O00303,Q9NZ08,P42892,Q10713,P55786,O75844,Q6P179,Q9UIQ6,P22695,O43847,Q5JRX3
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
263,199,134,372,80,467,18,150,436,62,123,312,30
134,2966,462,312,1989,150,879,2349,1563,2899,1991,123,3183,845,80,2484,1752,18,467,2433,3211,30,436,1018,2555,2833,2016,199,2195,1785,263,1486,831,3055,372,62,914,954
1.90070904556051,-0.7538691878397593,0.7468240195253295,1.0331289835246766,-0.23685790765018927,1.686517510151732,0.32253547644341873,-0.4049604270237952,-0.04561234257665679,-0.6944666864709049,-0.23685790765018927,2.0267654021496413,-0.9969079805068028,0.3481518092503356,2.474441012066322,-0.4618996447455134,-0.12695...
3,430
Receptor
8
42
2.578866
0.009913
O15031,Q99720,Q9NS69,O43731,O15118,P24390,P30825,Q14739
Functions
Protein Atlas Molecular function
protein_atlas_molecular_function
32,1,65,131,159,97,47,88
195,2750,32,159,375,131,2349,1874,961,2898,1614,2643,2223,1295,3366,2226,3334,1991,2761,2168,97,47,475,392,970,1147,1467,3125,88,2497,502,2883,752,906,2079,1,1436,65,2689,1977,1281,1604
1.4446118836303585,-0.6063272975273538,3.526456422078372,1.599340050103345,0.8912531522485077,1.9218433491723264,-0.4049604270237952,-0.1816960246922895,0.2710412960006848,-0.6944666864709049,-0.0726253190224832,-0.5481928052179911,-0.3484804617389532,0.08797608280824076,-1.6480344627031236,-0.3484804617389532,-1.41235...
3,430
Translocase
8
23
2.563619
0.010359
P16615,Q13423,Q03518,P00403,P03886,Q9HD20,P08183,P47985
Functions
Protein Atlas Molecular function
protein_atlas_molecular_function
404,135,41,205,48,113,29,407
1172,1731,673,1868,205,48,1873,1294,29,421,404,2527,658,2355,2711,2479,407,3117,41,1254,135,1774,113
0.14074080589325716,-0.1269547709677774,0.47495811622353734,-0.1816960246922895,1.3998810416079777,3.0334540690374134,-0.1816960246922895,0.08797608280824076,3.5620249416133856,0.8193657703584537,0.8434001246148884,-0.49054476129514196,0.5000697536260212,-0.4049604270237952,-0.5771985292104522,-0.4618996447455134,0.843...
3,430
Meiotic cell cycle process
14
46
2.561013
0.010437
Q9Y2W6,Q9BTX1,O15360,P42695,O43683,O95067,Q9BZD4,Q08J23,Q8IWV8,Q13315,O94901,Q14674,Q92791,P46379
Processes and pathways
GO Biological process
msigdb_gobp
33,98,164,349,345,347,168,297,11,235,490,496,91,285
604,1038,164,345,2971,1984,2640,490,347,2047,2588,3085,926,2233,1137,1404,349,285,2596,1302,1508,1625,3224,2118,2537,1051,297,536,235,496,1469,1414,1947,11,1701,91,1591,1322,98,865,168,2798,910,2403,33,836
0.5500494221591544,0.2191928482299109,1.57740694412931,0.9388225651180688,-0.7538691878397593,-0.23685790765018927,-0.5481928052179911,0.6980910015238436,0.9388225651180688,-0.2645994293667072,-0.5193086864663775,-0.8742752381374652,0.29683224780454964,-0.3484804617389532,0.16698324905786777,0.03483200299770884,0.93882...
3,430
Microbody membrane
10
26
2.547999
0.010834
Q9NP80,O75381,Q8TB36,O43808,O15228,P51648,O14975,Q9NR77,O14678,Q15067
Localization
GO Cellular component
msigdb_gocc
456,377,554,628,445,295,488,56,527,191
991,527,488,445,628,1452,377,1668,1563,1043,2110,1091,928,2114,295,2173,191,1900,664,1774,554,1776,1535,2019,456,56
0.24516178068886646,0.6490544769648282,0.6980910015238436,0.7710783389724302,0.5250999447143083,0.008115305624482679,0.8912531522485077,-0.09973910959887115,-0.04561234257665679,0.2191928482299109,-0.2924495622566737,0.1931336313940024,0.29683224780454964,-0.2924495622566737,1.0798749037476432,-0.3204095009349698,1.466...
3,430
Tetrapyrrole binding
9
18
2.528412
0.011458
Q9H7Z7,O15173,O00264,P09601,O43169,P30519,Q8WUJ1,Q16850,P53701
Functions
GO Molecular function
msigdb_gomf
200,375,195,202,43,79,20,212,409
195,375,43,421,202,2475,79,409,212,748,823,20,905,1432,200,2510,2464,2157
1.4446118836303585,0.8912531522485077,3.1636500931702374,0.8193657703584537,1.4222760763698468,-0.4618996447455134,2.474441012066322,0.8434001246148884,1.3774263391294397,0.4244875166555013,0.3736820608268665,3.996510780247743,0.32253547644341873,0.03483200299770884,1.4446118836303585,-0.4618996447455134,-0.43337197786...
3,430
Secondary alcohol metabolic process
15
46
2.527288
0.011495
Q9BQE5,O15118,P48735,P35610,O75874,Q14849,P54646,P05067,P48449,Q16850,Q14739,Q15392,P49748,O76062,P37268
Processes and pathways
GO Biological process
msigdb_gobp
34,159,100,320,226,71,122,293,13,212,88,26,120,93,94
159,1387,1805,2280,226,93,3142,2048,361,293,3223,2935,841,2976,1747,320,94,2715,13,100,120,3087,886,1407,3393,122,3276,3323,2242,3324,680,3124,573,88,71,3248,26,1471,1100,212,502,2886,34,668,1033,2745
1.599340050103345,0.03483200299770884,-0.1542733780946316,-0.3766636832817624,1.309699741732269,2.3545091190795486,-0.9353060839224018,-0.2645994293667072,0.9150730175796679,1.0798749037476432,-1.0590960879944016,-0.7241025980739512,0.3481518092503356,-0.7538691878397593,-0.1269547709677774,1.0096550230482197,2.3545091...
3,430
Episodic vomiting
8
12
2.523509
0.011619
Q2TAA5,Q9Y619,P00403,P03886,P61978,P36551,P49748,P22695
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
397,176,205,48,308,306,120,123
205,48,123,2478,306,120,308,397,1315,1277,456,176
1.3998810416079777,3.0334540690374134,2.0267654021496413,-0.4618996447455134,1.056535430788023,2.0683905572020973,1.056535430788023,0.8673623852267482,0.08797608280824076,0.11440539204641399,0.7710783389724302,1.555417548414023
3,430
Receptor
9
33
2.520433
0.011721
Q13432,O75381,Q9UQB8,Q567V2,Q8WTV0,A6NIH7,Q9UFC0,P57105,Q9NR77
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
315,377,8,9,502,12,216,179,56
12,1287,1554,1982,377,1806,1735,1874,2226,2761,3273,179,315,2543,3125,9,1476,1420,1209,502,2612,688,1649,2740,2023,539,948,56,2201,2689,216,2630,8
4.36447779033287,0.08797608280824076,-0.04561234257665679,-0.23685790765018927,0.8912531522485077,-0.1542733780946316,-0.1269547709677774,-0.1816960246922895,-0.3484804617389532,-0.6063272975273538,-1.185294978940291,1.5333714580911204,1.0331289835246766,-0.49054476129514196,-0.9047202020189336,4.956451323017112,0.0081...
3,430
Active transmembrane transporter activity
12
74
2.510794
0.012046
P53985,Q9UBX3,P51970,Q03518,Q96ES6,P03886,Q9HD20,O43676,Q02978,Q9P0J0,P14854,P08183
Functions
GO Molecular function
msigdb_gomf
198,133,197,41,15,48,113,52,24,153,124,29
1172,2340,527,1554,52,3139,1867,1731,673,1556,2412,1868,657,2641,1870,2103,807,205,48,1873,1737,1294,29,2859,421,1671,474,840,1673,124,404,2527,658,1500,2813,3402,2355,1043,2711,845,1502,2479,407,3117,966,197,1573,198,1142,2176,1515,24,41,1254,479,820,2497,2666,1636,823,3293,15,598,1119,113,3305,1656,153,133,603,2089,2...
0.14074080589325716,-0.4049604270237952,0.6490544769648282,-0.04561234257665679,2.977118417761843,-0.9353060839224018,-0.1816960246922895,-0.1269547709677774,0.47495811622353734,-0.04561234257665679,-0.43337197786310955,-0.1816960246922895,0.5000697536260212,-0.5481928052179911,-0.1816960246922895,-0.2924495622566737,0...
3,430
Abnormal csf metabolite level
9
59
2.479868
0.013143
P51970,Q96CU9,P03886,O95831,Q86Y39,Q9NWS8,O43676,Q9P0J0,P14854
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
197,76,48,17,145,111,52,153,124
1172,1920,2340,52,3139,2468,1731,673,1556,1868,3394,2103,17,807,205,48,2281,294,1673,124,2527,2711,1933,2712,1746,1138,2815,1885,3117,2653,197,2598,1347,1193,1253,2914,1636,1474,2498,1055,823,1156,145,2072,3363,1265,1061,2834,76,2317,2262,1845,2797,1228,111,540,153,873,922
0.14074080589325716,-0.20922382367890077,-0.4049604270237952,2.977118417761843,-0.9353060839224018,-0.4618996447455134,-0.1269547709677774,0.47495811622353734,-0.04561234257665679,-0.1816960246922895,-1.8928524961827435,-0.2924495622566737,4.298513011896481,0.3736820608268665,1.3998810416079777,3.0334540690374134,-0.37...
3,430
Regulation of atp metabolic process
6
28
2.459302
0.013921
P61586,P54646,P00403,Q9BSK2,P14406,P30536
Processes and pathways
GO Biological process
msigdb_gobp
161,122,205,21,22,90
1494,2408,1290,2043,205,2703,293,3311,1245,22,2901,1090,1934,90,963,678,2286,1887,122,1250,2428,161,1583,2606,2881,21,2573,2150
-0.018699141472303806,-0.43337197786310955,0.08797608280824076,-0.2645994293667072,1.3998810416079777,-0.5771985292104522,1.0798749037476432,-1.3140382639768318,0.11440539204641399,3.962414981690208,-0.6944666864709049,0.1931336313940024,-0.20922382367890077,2.374606434529858,0.2710412960006848,0.47495811622353734,-0.3...
3,430
Ion transmembrane transporter activity
20
95
2.431332
0.015043
Q9BQT8,P21796,Q9UBX3,Q13423,Q96ES6,Q70HW3,Q02978,O43772,Q93050,Q9Y619,P30825,Q8TB61,Q9H2D1,P53985,O75964,Q9Y487,P45880,Q9HD20,Q14728,P14854
Functions
GO Molecular function
msigdb_gomf
0,129,133,135,15,19,24,35,167,176,47,53,188,198,92,95,107,113,116,124
2515,304,35,628,2043,3222,92,1870,674,205,1873,1737,1294,2898,2756,3361,2859,421,2808,1671,294,474,840,1673,124,404,658,1500,2813,3402,129,2355,677,3242,47,845,3000,1502,2479,107,407,3350,966,1573,198,1142,2769,2175,2176,2535,1515,515,24,135,116,3247,479,2497,1359,3411,1901,3129,684,1477,19,823,857,3293,53,752,167,15,1...
-0.49054476129514196,1.056535430788023,3.3829136623223524,0.5250999447143083,-0.2645994293667072,-1.0590960879944016,2.3545091190795486,-0.1816960246922895,0.47495811622353734,1.3998810416079777,-0.1816960246922895,-0.1269547709677774,0.08797608280824076,-0.6944666864709049,-0.6063272975273538,-1.5797667609039607,-0.66...
3,430
Hormone metabolic process
8
29
2.41668
0.015663
Q14849,O94788,P42892,O95470,O75844,Q53GQ0,P30536,Q6NUM9
Processes and pathways
GO Biological process
msigdb_gobp
71,231,80,117,150,247,90,287
1391,150,231,117,1873,1991,2812,841,90,1140,80,2595,2173,3276,1759,680,71,2434,247,287,2128,2073,1160,3014,2262,358,1033,2207,1078
0.03483200299770884,1.686517510151732,1.287001856899264,2.089130764535109,-0.1816960246922895,-0.23685790765018927,-0.6355805774220161,0.3481518092503356,2.374606434529858,0.16698324905786777,2.474441012066322,-0.5193086864663775,-0.3204095009349698,-1.185294978940291,-0.1269547709677774,0.47495811622353734,2.670952039...
3,430
Abnormality of the metaphysis
12
56
2.402104
0.016301
Q07864,O95613,Q9P2D1,P48735,O75874,P16278,Q99575,Q96HY6,O95831,Q13126,Q96L58,Q14739
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
351,337,426,100,226,7,333,332,17,49,147,88
1447,3177,2277,837,1452,1606,226,2044,1131,337,17,2164,2703,3269,2705,1560,7,3167,962,1138,2053,531,100,2114,966,3187,1098,1147,1759,351,49,88,2368,433,1203,2829,1317,1320,2922,332,147,689,333,1434,867,2142,1165,2687,426,2629,833,1123,2845,2631,1444,2846
0.008115305624482679,-0.9969079805068028,-0.3766636832817624,0.3481518092503356,0.008115305624482679,-0.0726253190224832,1.309699741732269,-0.2645994293667072,0.16698324905786777,0.9625023709095525,4.298513011896481,-0.3204095009349698,-0.5771985292104522,-1.185294978940291,-0.5771985292104522,-0.04561234257665679,5.04...
3,430
Oxidoreductase activity acting on the ch ch group of donors
11
31
2.393793
0.016675
P21912,Q14914,Q8N4Q0,Q9H7Z7,O15254,O76062,Q14739,Q15392,P49748,Q6NUM9,Q15067
Functions
GO Molecular function
msigdb_gomf
253,5,6,200,201,93,88,26,120,287,191
201,93,3320,3415,253,2169,1746,306,3313,1300,120,2651,1819,88,5,191,26,287,940,823,6,3408,2078,2447,693,3398,200,1118,3175,562,1033
1.4222760763698468,2.3545091190795486,-1.3794099034207994,-2.6017806108411556,1.1955860310511912,-0.3204095009349698,-0.1269547709677774,1.056535430788023,-1.3140382639768318,0.08797608280824076,2.0683905572020973,-0.5481928052179911,-0.1542733780946316,2.414669876898858,5.339395472818971,1.4668888982985397,3.824905510...
3,430
Positive regulation of translation
12
60
2.386938
0.016989
O15031,P08670,P61586,Q567V2,P42345,Q14103,P67809,Q9NWS8,P78527,O60506,P98179,Q9Y2R0
Processes and pathways
GO Biological process
msigdb_gobp
32,252,161,9,266,236,237,111,273,207,255,318
1079,32,2098,2752,207,1923,2705,252,707,1564,2417,2907,266,1816,1299,533,548,2428,849,1511,161,3145,1189,934,237,2717,273,255,817,2661,781,743,362,1194,1826,3068,1006,236,2249,9,1765,1585,1016,1156,976,1211,1213,2444,2560,690,1965,2569,2393,1851,1223,111,2840,2511,318,836
0.1931336313940024,3.526456422078372,-0.2924495622566737,-0.6063272975273538,1.3774263391294397,-0.20922382367890077,-0.5771985292104522,1.1955860310511912,0.4497642888546631,-0.04561234257665679,-0.43337197786310955,-0.6944666864709049,1.1494967612733409,-0.1542733780946316,0.08797608280824076,0.6490544769648282,0.624...
3,430
Decreased activity of mitochondrial complex i
7
36
2.385945
0.017035
Q9UBX3,P51970,Q96CU9,P03886,Q86Y39,Q70HW3,O43676
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
133,197,76,48,145,19,52
1172,52,1731,673,1556,1868,838,807,48,2527,2711,1815,3117,197,2868,2598,498,2954,19,145,2072,1061,2734,76,904,2317,1845,3019,1118,1071,2797,540,133,1978,230,922
0.14074080589325716,2.977118417761843,-0.1269547709677774,0.47495811622353734,-0.04561234257665679,-0.1816960246922895,0.3481518092503356,0.3736820608268665,3.0334540690374134,-0.49054476129514196,-0.5771985292104522,-0.1542733780946316,-0.9047202020189336,1.4446118836303585,-0.6649598650903187,-0.5193086864663775,0.69...
3,430
Inner mitochondrial membrane organization
7
22
2.379482
0.017337
Q9Y584,Q9Y5J9,O75431,Q9P0J0,Q9Y512,Q13505,Q9Y5L4
Processes and pathways
GO Biological process
msigdb_gobp
230,99,171,153,154,155,57
1390,171,1924,1870,3299,155,1009,1696,1360,1421,1266,1029,3133,987,2457,153,954,154,230,390,99,57
0.03483200299770884,1.555417548414023,-0.20922382367890077,-0.1816960246922895,-1.2493396154375127,1.643038988747382,0.24516178068886646,-0.09973910959887115,0.061451938274776984,0.03483200299770884,0.11440539204641399,0.24516178068886646,-0.9047202020189336,0.2710412960006848,-0.43337197786310955,1.6648056078317892,0....
3,430
Inner mitochondrial membrane protein complex
23
76
2.376628
0.017472
P21912,O14949,Q86Y39,P14406,Q9P0J0,Q9Y512,Q13505,P47985,O75431,P03886,O43676,Q99595,P51970,Q96CU9,P00403,Q8IYU8,O60830,O75964,Q9Y584,Q3ZCQ8,Q9Y5J7,P22695,P14854
Localization
GO Cellular component
msigdb_gocc
253,265,145,22,153,154,155,407,171,48,52,184,197,76,205,213,82,92,230,353,390,123,124
1172,2340,461,265,52,3139,82,1731,673,1556,171,2412,1868,3222,92,657,2641,2103,807,205,48,1294,421,1927,1671,840,1673,22,124,3424,3031,2527,1500,253,123,677,3242,2711,1746,845,3144,3000,3299,407,3350,3117,197,2769,2175,155,2666,1636,1009,353,1696,1360,1421,145,213,3293,76,578,184,2079,1029,2625,987,2457,153,603,2153,95...
0.14074080589325716,-0.4049604270237952,0.7468240195253295,1.1494967612733409,2.977118417761843,-0.9353060839224018,2.454560157968432,-0.1269547709677774,0.47495811622353734,-0.04561234257665679,1.555417548414023,-0.43337197786310955,-0.1816960246922895,-1.0590960879944016,2.3545091190795486,0.5000697536260212,-0.54819...
3,430
Bulbar signs
6
13
2.369977
0.017789
P07602,Q99720,P35637,P03886,P04062,O43681
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
128,1,326,48,361,304
304,48,361,1612,128,1088,326,998,479,1960,1,625,1280
1.056535430788023,3.0334540690374134,0.9150730175796679,-0.0726253190224832,1.9639610723159058,0.1931336313940024,0.9861130032940525,0.24516178068886646,0.7224951214644277,-0.20922382367890077,6.5825180808654515,0.5500494221591544,0.11440539204641399
3,430
Biological oxidations
7
48
2.359619
0.018294
O15217,P07099,Q9NUJ1,Q8WUX2,O43169,P30837,Q8TB61
Processes and pathways
Reactome Pathways
msigdb_reactome
96,2,4,138,43,211,53
1127,1449,96,43,2276,3331,2804,2343,1987,3317,2048,1610,2,2107,3061,3084,2810,841,1992,1877,2976,1878,3114,211,2979,2112,1503,1750,740,1192,610,680,537,212,3008,3192,53,138,1063,1064,1215,2195,1432,2679,2394,4,2028,2513
0.16698324905786777,0.008115305624482679,2.3141819588828207,3.1636500931702374,-0.3766636832817624,-1.4123542758389538,-0.6355805774220161,-0.4049604270237952,-0.23685790765018927,-1.3466387383865048,-0.2645994293667072,-0.0726253190224832,6.25214098820279,-0.2924495622566737,-0.8439693958817623,-0.8742752381374652,-0....
3,430
Tachycardia
6
30
2.354845
0.01853
P21912,O43772,P09493,P42892,P49748,P23786
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
253,35,140,80,120,89
35,1243,1733,2221,2049,2415,140,633,1929,1398,2862,253,89,3389,306,2714,80,1749,120,2651,1631,1355,819,1646,1318,1320,1594,1116,755,1278
3.3829136623223524,0.11440539204641399,-0.1269547709677774,-0.3484804617389532,-0.2645994293667072,-0.43337197786310955,1.8370003037552247,0.5250999447143083,-0.20922382367890077,0.03483200299770884,-0.6649598650903187,1.1955860310511912,2.374606434529858,-1.8219801498532384,1.056535430788023,-0.5771985292104522,2.4744...
3,430
Abnormal renal cortex morphology
10
57
2.330047
0.019804
P21912,Q6PGP7,Q9NZ08,P52429,P00403,O75431,P03886,O95470,Q02978,Q16134
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
253,37,372,45,205,171,48,117,24,60
1174,1241,1388,1243,1452,171,1733,2104,117,205,379,2221,48,3297,2858,2225,3205,1179,1676,253,1746,2865,2906,2815,1300,45,1459,1047,968,2535,1098,24,2290,2182,971,1306,3125,2369,1309,60,3009,2550,37,723,751,3235,2130,645,1320,695,1225,2268,372,2087,2095,2464,2695
0.14074080589325716,0.11440539204641399,0.03483200299770884,0.11440539204641399,0.008115305624482679,1.555417548414023,-0.1269547709677774,-0.2924495622566737,2.089130764535109,1.3998810416079777,0.8912531522485077,-0.3484804617389532,3.0334540690374134,-1.2493396154375127,-0.6649598650903187,-0.3484804617389532,-1.027...
3,430
Optic disc pallor
12
50
2.323756
0.020139
Q9BUK6,O14936,Q96CU9,P03886,Q86Y39,O95831,Q96L58,Q9Y287,O43676,Q10713,Q9H061,Q92974
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
324,508,76,48,145,17,147,416,52,467,25,386
1172,1494,3346,2697,508,1981,52,1387,1390,1731,673,1556,1989,1868,1292,17,807,48,588,2525,1931,2527,2711,3117,966,3261,467,1197,1477,2726,145,2611,2072,979,1061,2501,386,76,147,1111,1845,324,25,1541,2797,540,1123,416,954,922
0.14074080589325716,-0.018699141472303806,-1.4787730194604598,-0.5771985292104522,0.6736110072791157,-0.23685790765018927,2.977118417761843,0.03483200299770884,0.03483200299770884,-0.1269547709677774,0.47495811622353734,-0.04561234257665679,-0.23685790765018927,-0.1816960246922895,0.08797608280824076,4.298513011896481,...
3,430
Protein transmembrane transport
9
25
2.309817
0.020898
Q9NS69,Q9Y584,O75381,Q3ZCQ8,O43615,O95831,O60830,Q15629,Q99595
Processes and pathways
GO Biological process
msigdb_gobp
65,230,377,353,10,17,82,275,184
461,10,82,377,1924,17,2897,3271,1296,965,2114,3356,3187,2535,890,820,275,353,2381,1431,184,2625,65,1034,230
0.7468240195253295,4.430040959592227,2.454560157968432,0.8912531522485077,-0.20922382367890077,4.298513011896481,-0.6944666864709049,-1.185294978940291,0.08797608280824076,0.2710412960006848,-0.2924495622566737,-1.5459163719143243,-0.9969079805068028,-0.49054476129514196,0.32253547644341873,0.3736820608268665,1.1263550...
3,430
Clonus
11
35
2.30842
0.020976
P07602,Q99720,Q9BQT8,P49589,Q9Y5P6,Q3ZCQ8,Q9Y619,P35637,P42858,Q15043,Q9H9S5
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
128,1,0,350,526,353,176,326,338,479,525
2215,1867,1805,3354,3142,3109,128,3341,2354,326,1406,338,2235,350,1253,742,1098,1352,536,479,353,1314,3072,977,1837,1,0,525,1653,1715,625,2207,917,526,176
-0.3484804617389532,-0.1816960246922895,-0.1542733780946316,-1.5459163719143243,-0.9353060839224018,-0.9047202020189336,1.9639610723159058,-1.4454744338975105,-0.4049604270237952,0.9861130032940525,0.03483200299770884,0.9625023709095525,-0.3484804617389532,0.9388225651180688,0.11440539204641399,0.4244875166555013,0.193...
3,430
Metalloendopeptidase activity
6
14
2.29113
0.021956
Q99797,P42892,O75844,P22695,O43847,Q5JRX3
Functions
GO Molecular function
msigdb_gomf
263,80,150,123,312,30
312,1989,150,1991,123,80,1752,467,30,2016,1785,263,831,954
1.0331289835246766,-0.23685790765018927,1.686517510151732,-0.23685790765018927,2.0267654021496413,2.474441012066322,-0.1269547709677774,0.7468240195253295,3.5620249416133856,-0.23685790765018927,-0.1269547709677774,1.1725735874859986,0.3736820608268665,0.29683224780454964
3,430
Cation transmembrane transporter activity
11
65
2.284986
0.022314
O43772,Q93050,Q13423,Q9Y619,Q96ES6,P30825,P14854,Q9HD20,Q70HW3,O75964,Q9Y487
Functions
GO Molecular function
msigdb_gomf
35,167,135,176,15,47,124,113,19,92,95
35,628,3222,92,1870,205,1873,1737,1294,2898,2756,3361,2859,421,1671,474,1673,124,404,658,1500,2813,3402,2355,677,3242,47,845,3000,1502,2479,407,3350,1142,2769,2175,2176,2535,1515,515,135,479,2497,1359,1477,19,823,3293,752,167,15,1218,2080,598,2199,1119,2024,113,603,2089,2032,95,2991,176,763
3.3829136623223524,0.5250999447143083,-1.0590960879944016,2.3545091190795486,-0.1816960246922895,1.3998810416079777,-0.1816960246922895,-0.1269547709677774,0.08797608280824076,-0.6944666864709049,-0.6063272975273538,-1.5797667609039607,-0.6649598650903187,0.8193657703584537,-0.09973910959887115,0.7224951214644277,-0.09...
3,430
Submucous cleft of soft and hard palate
10
24
2.279498
0.022637
P49589,O43505,Q08J23,Q9Y619,Q7LGA3,Q8NAT1,O75844,Q15392,Q9H9S5,P48651
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
350,376,297,176,174,439,150,26,525,531
1384,2698,376,150,2221,2708,1091,531,350,549,1304,297,1633,2546,26,174,2012,439,1268,1326,525,2272,3282,176
0.03483200299770884,-0.5771985292104522,0.8912531522485077,1.686517510151732,-0.3484804617389532,-0.5771985292104522,0.1931336313940024,0.6490544769648282,0.9388225651180688,0.6244207392875576,0.08797608280824076,1.0798749037476432,-0.0726253190224832,-0.49054476129514196,3.8249055103577976,1.555417548414023,-0.2368579...
3,430
Contractures of the joints of the upper limbs
10
73
2.274559
0.022932
Q99720,Q13535,Q9Y619,P42892,Q96L58,O75844,Q9NR77,P23786,Q15392,P37268
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
1,136,176,80,147,150,56,89,26,94
1447,3219,2697,1385,2698,2277,837,1388,489,2851,150,3142,705,2221,1612,1613,1296,841,774,3167,2167,89,513,3032,1882,326,94,80,3274,531,591,2114,2653,888,2534,968,1098,2181,136,2062,3038,1827,2368,433,1763,26,2069,2550,174,722,2130,1426,2561,2017,354,147,2388,1114,1,1326,755,1596,2569,1069,56,2459,2034,2845,2095,2633,91...
0.008115305624482679,-1.0590960879944016,-0.5771985292104522,0.03483200299770884,-0.5771985292104522,-0.3766636832817624,0.3481518092503356,0.03483200299770884,0.6980910015238436,-0.6649598650903187,1.686517510151732,-0.9353060839224018,0.4497642888546631,-0.3484804617389532,-0.0726253190224832,-0.0726253190224832,0.08...
3,430
Micromelia
8
24
2.266656
0.023411
P48735,O75874,Q96HY6,O75718,Q9UHX1,O95613,Q15392,Q14739
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
100,226,332,178,84,337,26,88
2038,3177,2698,2971,1607,2852,178,226,337,1086,100,2597,351,1827,88,26,2550,1317,332,2629,1033,84,2152,3282
-0.2645994293667072,-0.9969079805068028,-0.5771985292104522,-0.7538691878397593,-0.0726253190224832,-0.6649598650903187,1.5333714580911204,1.309699741732269,0.9625023709095525,0.1931336313940024,2.273676273543026,-0.5193086864663775,0.9388225651180688,-0.1542733780946316,2.414669876898858,3.8249055103577976,-0.49054476...
3,430
Abnormal activity of mitochondrial respiratory chain
11
54
2.264092
0.023568
P21912,Q9Y584,Q9UBX3,P51970,Q96CU9,P03886,Q86Y39,Q70HW3,O43676,Q9P0J0,Q9Y2R0
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
253,230,133,197,76,48,145,19,52,153,318
1172,2340,52,3139,1731,673,1556,1868,838,2103,807,48,2281,1673,2527,1500,253,2711,2712,1746,1885,1815,3117,197,2868,2598,550,2914,1636,353,498,2954,19,823,145,2072,1061,2734,76,904,2317,1845,3019,1118,1071,2797,540,153,3100,133,318,1978,230,922
0.14074080589325716,-0.4049604270237952,2.977118417761843,-0.9353060839224018,-0.1269547709677774,0.47495811622353734,-0.04561234257665679,-0.1816960246922895,0.3481518092503356,-0.2924495622566737,0.3736820608268665,3.0334540690374134,-0.3766636832817624,-0.09973910959887115,-0.49054476129514196,-0.018699141472303806,...
3,430
Abnormality of the calf
11
66
2.256357
0.024048
Q32P28,P16278,Q13535,Q9Y619,Q15427,Q7LGA3,O75431,O95831,Q13126,Q96L58,Q9NR77
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
137,7,136,176,141,174,171,17,49,147,56
3219,3346,3177,1921,2470,2852,171,178,2854,337,2348,17,2164,2703,3269,995,2899,7,841,1181,3312,3167,1676,1742,962,2170,1091,1138,2907,2597,966,2773,1253,1098,1304,1147,2432,49,136,2368,1898,141,3008,137,174,2829,977,1317,3235,2922,332,147,867,2142,56,1165,2326,426,1440,2459,2034,1036,3217,803,487,176
-1.0590960879944016,-1.4787730194604598,-0.9969079805068028,-0.20922382367890077,-0.4618996447455134,-0.6649598650903187,1.555417548414023,1.5333714580911204,-0.6649598650903187,0.9625023709095525,-0.4049604270237952,4.298513011896481,-0.3204095009349698,-0.5771985292104522,-1.185294978940291,0.24516178068886646,-0.694...
3,430
Cellular hormone metabolic process
7
19
2.250845
0.024395
O94788,Q14849,P42892,O95470,Q53GQ0,P30536,Q6NUM9
Processes and pathways
GO Biological process
msigdb_gobp
231,71,80,117,247,90,287
1391,231,117,2812,90,1140,80,2173,3276,71,2434,247,287,2128,2073,1160,2262,358,1078
0.03483200299770884,1.287001856899264,2.089130764535109,-0.6355805774220161,2.374606434529858,0.16698324905786777,2.474441012066322,-0.3204095009349698,-1.185294978940291,2.6709520398634075,-0.43337197786310955,1.2185345905694018,1.1031479342874442,-0.2924495622566737,-0.2645994293667072,0.16698324905786777,-0.34848046...
3,430
Abnormal circulating carbohydrate concentration
7
41
2.240788
0.02504
Q96CU9,P03886,O95831,Q70HW3,O43676,P22695,Q5JRX3
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
76,48,17,19,52,123,30
1172,1920,52,1731,673,1556,1868,17,807,3081,48,2281,3341,2527,253,123,2711,3298,1138,3117,3119,2653,3262,352,2914,30,19,2918,145,2072,1061,76,650,1845,506,456,2797,540,1381,2153,922
0.14074080589325716,-0.20922382367890077,2.977118417761843,-0.1269547709677774,0.47495811622353734,-0.04561234257665679,-0.1816960246922895,4.298513011896481,0.3736820608268665,-0.8742752381374652,3.0334540690374134,-0.3766636832817624,-1.4454744338975105,-0.49054476129514196,1.1955860310511912,2.0267654021496413,-0.57...
3,430
Peptide catabolic process
7
11
2.238304
0.025201
P09960,Q9NQW7,Q8WUX2,Q9NZ08,P42892,P55786,Q9UIQ6
Processes and pathways
GO Biological process
msigdb_gobp
403,402,138,372,80,18,62
1726,403,1991,80,18,436,138,3304,402,372,62
-0.1269547709677774,0.8434001246148884,-0.23685790765018927,2.474441012066322,4.198797593874944,0.7952587140908609,1.8795239983176255,-1.2493396154375127,0.8673623852267482,0.9150730175796679,2.901489927522586
3,430
Dehydrogenase
11
58
2.23785
0.025231
P21912,Q14914,Q8N4Q0,P51970,Q13423,O94788,Q96CU9,P03886,O95831,P30837,Q9P0J0
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
253,5,6,197,135,231,76,48,17,211,153
1172,2698,1387,1731,673,2412,231,17,3081,960,1872,48,2586,1610,3083,1085,3223,3084,1397,253,1501,883,2711,3298,211,1746,3206,3259,2815,1458,2595,3422,3087,886,1572,197,2942,1819,888,3262,2775,135,5,1636,3041,2299,2440,1646,6,3408,2014,1160,76,2262,2140,562,153,303
0.14074080589325716,-0.5771985292104522,0.03483200299770884,-0.1269547709677774,0.47495811622353734,-0.43337197786310955,1.287001856899264,4.298513011896481,-0.8742752381374652,0.2710412960006848,-0.1816960246922895,3.0334540690374134,-0.5193086864663775,-0.0726253190224832,-0.8742752381374652,0.1931336313940024,-1.059...
3,430
Goiter
6
7
2.229171
0.025803
P21912,P12235,P48735,O75874,Q9UNW1,Q96RR1
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
253,474,100,226,374,650
226,474,253,100,650,374,655
1.309699741732269,0.7224951214644277,1.1955860310511912,2.273676273543026,0.5250999447143083,0.9150730175796679,0.5250999447143083
3,430
Mitochondrial myopathy
10
28
2.21761
0.026581
Q9NP80,P12235,Q9BUK6,Q96CU9,P00403,P03886,Q86Y39,Q9P032,O43676,Q96RR1
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
456,474,324,76,205,48,145,540,52,650
1172,52,1390,1731,673,1556,1868,807,205,48,474,2527,2711,3117,1696,145,2072,1061,76,650,1845,324,456,2797,540,2094,2037,922
0.14074080589325716,2.977118417761843,0.03483200299770884,-0.1269547709677774,0.47495811622353734,-0.04561234257665679,-0.1816960246922895,0.3736820608268665,1.3998810416079777,3.0334540690374134,0.7224951214644277,-0.49054476129514196,-0.5771985292104522,-0.9047202020189336,-0.09973910959887115,1.7728255266677748,-0.2...
3,430