term
stringlengths 2
121
| overlap
int64 6
281
| setsize
int64 7
499
| score
float64 1.96
10.6
| pval
float64 0
0.05
| edge
stringlengths 41
1.97k
| type
stringclasses 5
values | subtype
stringclasses 24
values | subtype_key
stringclasses 24
values | edge_idxs
stringlengths 11
1.17k
| ann_idxs
stringlengths 19
2.31k
| ann_vals
stringlengths 124
9.94k
| sig_size
int64 2.2k
3.73k
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Hydrolase activity hydrolyzing o glycosyl compounds
| 12
| 23
| 3.594427
| 0.000325
|
P17900,O60476,Q9BTY2,P16278,P06865,P06280,O60502,P54802,P10253,P08236,Q9NUJ1,P04062
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
66,227,202,43,268,275,147,87,311,279,221,30
|
977,227,147,30,895,275,268,1358,279,311,43,66,1224,87,741,1646,1202,551,2756,340,202,221,2712
|
0.33701658189477507,1.5916594876052144,1.904751655596212,3.0603364192521147,0.41529180787632924,1.4151493408700357,1.4279535786684734,0.09468784334280253,1.402314093228658,1.3246420617522143,2.9065277890482055,2.4918352621956807,0.17675834803240076,2.321161071650228,0.5833929390939195,-0.0564914375226667,0.19301386899346543,0.8041129767098191,-0.7116898323792509,1.2590315225380515,1.7142527679704935,1.6287336796515217,-0.6729168790091554
| 3,430
|
Active ion transmembrane transporter activity
| 25
| 38
| 3.581395
| 0.000342
|
P20020,P51798,Q7KZN9,P16615,O95202,P31930,Q9Y6M7,P00403,P12236,Q9HD20,Q96ES6,P08574,P06576,P23634,Q15043,Q02978,P55011,Q9UDW1,P13073,Q9BXP2,Q00325,P12235,P05023,P05141,P14854
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
385,524,525,269,401,784,548,28,418,35,37,296,674,819,191,696,574,74,336,601,214,213,607,736,363
|
401,28,607,736,674,1567,296,840,213,418,336,363,269,385,1119,3191,3343,819,784,2149,2748,1075,524,1100,574,1259,214,696,191,525,37,601,1409,35,74,2136,2067,548
|
1.0981470112960925,3.0698107589013315,0.7169539114401163,0.5833929390939195,0.6431811538013191,-0.02250118346835699,1.3636206339195902,0.4616874064468927,1.641034754600386,1.057143066123191,1.2590315225380515,1.1925938145223307,1.4279535786684734,1.1388325289942267,0.24146991514915547,-1.2028041638743916,-1.7500104946959263,0.47705956297724367,0.522901157152449,-0.30111518243997987,-0.7116898323792509,0.2735187641595761,0.861414936766202,0.25751962221115077,0.7607169539788241,0.1604504658814682,1.641034754600386,0.6282990804246098,1.750489731196436,0.861414936766202,3.0222783212407616,0.7315827923762055,0.07811250742307049,3.0318170762153325,2.4178172840822203,-0.2832385860448953,-0.24767692023999524,0.8184979173823138
| 3,430
|
Vacuole organization
| 13
| 53
| 3.565579
| 0.000363
|
P42345,O14773,O75503,Q96GC9,P16615,Q8TBX8,P50897,P04062,P10253,Q8N511,P54802,Q14108,Q14457
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
353,162,104,188,269,242,22,30,311,25,87,60,287
|
2026,162,1186,104,1639,2285,1565,3286,30,1952,1358,311,370,269,353,1363,22,1364,87,2970,2186,2004,550,60,287,1488,1583,551,812,2052,730,902,25,242,1301,1624,188,2759,3158,2206,1466,1730,2400,1504,1050,2475,2875,1845,2315,1768,3222,2452,2317
|
-0.24767692023999524,1.8577557582221775,0.19301386899346543,2.189571052524327,-0.0564914375226667,-0.373271876429598,-0.02250118346835699,-1.4913543909405875,3.0603364192521147,-0.2123673195994045,0.09468784334280253,1.3246420617522143,1.179204988513675,1.4279535786684734,1.2192696206606266,0.09468784334280253,3.191546309151074,0.09468784334280253,2.321161071650228,-0.9103121062691136,-0.31905629408571334,-0.22999085661134913,0.8041129767098191,2.5336885717746562,1.3894476706931538,0.02805701137235168,-0.02250118346835699,0.8041129767098191,0.4923857069491886,-0.24767692023999524,0.5984052493734849,0.41529180787632924,3.1263237819839285,1.5418228550895896,0.14408985151272588,-0.03946755021715677,1.7625145060761207,-0.7116898323792509,-1.1386163266404463,-0.31905629408571334,0.04479749007284595,-0.0907134950668146,-0.4280869276823581,0.02805701137235168,0.30536674022651894,-0.4835161673691688,-0.8099892376198776,-0.1424888753229872,-0.373271876429598,-0.10791253841717666,-1.267862233870033,-0.4649705794159142,-0.373271876429598
| 3,430
|
Vesicles
| 64
| 328
| 3.55975
| 0.000371
|
Q96K76,P24390,Q9NRY5,Q92564,P67809,O14734,O15460,Q13315,P06865,P35613,Q8IYR2,P50897,Q15907,Q8TAF3,Q14849,P21964,P08236,Q9NUD5,Q32P28,Q9HD20,Q96ES6,P07602,Q8WTV0,P16278,P30519,Q13595,Q9H2V7,Q9Y487,Q13277,Q9H8H2,A1L0T0,Q8TB61,P10253,P13674,Q9Y287,O60506,P17900,Q3SXM5,O15127,Q96L92,P05067,P42785,Q99519,O95302,Q9HD45,Q8NCC3,Q92791,Q93050,Q8NBX0,P42345,P10619,Q5BKZ1,P16435,Q6P4A7,Q9NPR9,P13473,O15118,Q86V85,Q96JB5,Q96SK2,Q9Y2G8,Q14534,O76062,O75153
|
Localization
|
Protein Atlas Subcellular
|
protein_atlas_subcellular_location_all
|
255,6,135,8,396,391,398,400,268,270,404,22,276,152,27,280,279,417,34,35,37,38,169,43,44,301,46,175,427,178,54,55,311,314,190,187,66,67,72,330,205,207,340,333,90,91,219,220,95,353,226,355,231,232,107,237,109,245,373,374,248,122,382,127
|
54,1662,1559,1389,977,2816,391,2027,2428,1353,2215,1560,794,2378,109,72,1663,398,3098,2501,187,1473,2408,2479,1603,127,870,2410,2693,782,802,1250,382,2897,2071,2947,333,1810,1605,618,1910,1702,1951,895,2717,205,268,38,279,3126,3233,3288,2147,311,226,2108,1509,1705,237,314,1537,1538,3350,43,231,1444,66,3142,3191,280,6,495,3164,2640,874,44,1318,1571,270,1032,2183,2748,1912,2358,353,2601,207,2001,3103,3104,775,1962,2290,1914,677,862,1163,22,1011,805,510,2929,1964,2953,3105,2670,1573,574,1965,3360,1292,2186,2042,2702,1752,2804,396,1783,558,1296,2649,1578,3253,2557,2579,1514,427,400,2704,2089,301,2234,949,1617,2881,1321,122,637,2155,1788,27,1125,2825,2512,3130,3410,2330,809,2826,1126,3016,276,1518,34,67,1455,951,1675,355,1375,1204,1323,2841,2866,2531,2331,812,2051,1151,2193,232,2977,514,3399,824,1897,730,2868,1723,1546,3072,245,2999,2756,902,453,1724,766,2303,1974,3313,846,404,1898,2910,492,515,2728,3425,1266,95,2680,1496,91,3355,2117,152,55,169,1757,1268,3019,3155,8,1208,1524,1977,219,1834,220,3370,1427,719,582,37,1428,1344,3118,685,373,255,686,330,1550,2759,2684,2424,374,564,1937,340,1272,1590,1798,2313,2062,758,1045,3422,2659,3428,1431,1800,3171,458,1942,2471,3231,2398,1408,1048,46,2685,748,178,1276,35,90,2132,2280,107,2521,1802,1384,2208,1501,135,2342,1502,3173,417,3058,3021,3372,2103,1528,1805,1871,2473,2814,975,2893,1767,1068,1906,1386,3096,3278,2660,2447,733,2137,1843,923,2689,956,2739,435,1695,190,248,633,1696,3212,1054,2985,2213,175,2404,2741,2815,891,670,924,1771,2690,1558,2068
|
2.6267135515683826,-0.07357327446040215,-0.02250118346835699,0.07811250742307049,0.33701658189477507,-0.7704316844994457,1.125305736257329,-0.24767692023999524,-0.4649705794159142,0.09468784334280253,-0.33706243340680064,-0.02250118346835699,0.5076661391022604,-0.4280869276823581,2.1784605959005607,2.4284524960951095,-0.07357327446040215,1.1117439633053623,-1.0543430004362901,-0.5208177336190014,1.7625145060761207,0.02805701137235168,-0.4464943548499513,-0.5021316919187672,-0.03946755021715677,2.0547236877093185,0.43080383738421585,-0.4464943548499513,-0.6729168790091554,0.522901157152449,0.4923857069491886,0.1604504658814682,1.1523245386286525,-0.8498704751461239,-0.26542599868242417,-0.8900812583352817,1.2590315225380515,-0.1424888753229872,-0.03946755021715677,0.7022834886797121,-0.1948058268211105,-0.0907134950668146,-0.2123673195994045,0.41529180787632924,-0.6922649775615227,1.6777690135569574,1.4279535786684734,3.0127233121243298,1.402314093228658,-1.096295452188383,-1.3117306703903504,-1.4913543909405875,-0.30111518243997987,1.3246420617522143,1.6040461907838122,-0.2832385860448953,0.01126068031324202,-0.0907134950668146,1.554325783520826,1.311585046538852,-0.005591913085313469,-0.005591913085313469,-1.7986048232476497,2.9065277890482055,1.5792439505261,0.04479749007284595,2.4918352621956807,-1.117409393747407,-1.2028041638743916,1.402314093228658,3.713359366894026,0.903980231650309,-1.1599171531024435,-0.6344483133432426,0.43080383738421585,2.8378826071016987,0.1276761298241045,-0.02250118346835699,1.4279535786684734,0.30536674022651894,-0.31905629408571334,-0.7116898323792509,-0.1948058268211105,-0.40974773902190176,1.2192696206606266,-0.596278947334594,1.6777690135569574,-0.22999085661134913,-1.0543430004362901,-1.0543430004362901,0.5380910558331444,-0.2123673195994045,-0.373271876429598,-0.1948058268211105,0.6431811538013191,0.44626893355334946,0.20921739577808898,3.191546309151074,0.32121625895525563,0.4923857069491886,0.8756421363992508,-0.8699343008139493,-0.2123673195994045,-0.8900812583352817,-1.0543430004362901,-0.6536448751928122,-0.02250118346835699,0.7607169539788241,-0.2123673195994045,-1.8477085071425041,0.14408985151272588,-0.31905629408571334,-0.24767692023999524,-0.6729168790091554,-0.10791253841717666,-0.7507725016906376,1.125305736257329,-0.12517084870498654,0.7896879996375533,0.14408985151272588,-0.6344483133432426,-0.02250118346835699,-1.3560056220962575,-0.558403728184664,-0.5773048800496771,0.01126068031324202,1.04340337414266,1.1117439633053623,-0.6729168790091554,-0.26542599868242417,1.3506596827179598,-0.33706243340680064,0.36847097049977656,-0.03946755021715677,-0.8298890333091614,0.1276761298241045,2.077431989617715,0.6875712647067221,-0.30111518243997987,-0.12517084870498654,3.0792691433168833,0.24146991514915547,-0.7704316844994457,-0.5208177336190014,-1.096295452188383,-2.713839159385279,-0.3914762369552328,0.4923857069491886,-0.7704316844994457,0.24146991514915547,-0.9510285615071858,1.4151493408700357,0.01126068031324202,3.0318170762153325,2.4918352621956807,0.04479749007284595,0.36847097049977656,-0.07357327446040215,1.2192696206606266,0.09468784334280253,0.19301386899346543,0.1276761298241045,-0.7901703605422196,-0.8099892376198776,-0.5395748804972572,-0.3914762369552328,0.4923857069491886,-0.24767692023999524,0.22536929144369766,-0.31905629408571334,1.5792439505261,-0.9103121062691136,0.8756421363992508,-2.314670312494451,0.47705956297724367,-0.1773059016141884,0.5984052493734849,-0.8099892376198776,-0.0907134950668146,-0.005591913085313469,-1.0127520150653435,1.5292904957224467,-0.9306276139125141,-0.7116898323792509,0.41529180787632924,0.98808050071691,-0.0907134950668146,0.5532361269354006,-0.373271876429598,-0.2123673195994045,-1.5605037593216007,0.4616874064468927,1.0981470112960925,-0.1773059016141884,-0.8498704751461239,0.9180915884762,0.8756421363992508,-0.6922649775615227,-4.348155832158833,0.1604504658814682,2.244786155021276,-0.6536448751928122,0.02805701137235168,2.277649032464161,-1.8230922651443087,-0.2832385860448953,1.8930410423267858,2.606176282501621,1.8459424393187207,-0.10791253841717666,0.1604504658814682,-0.9510285615071858,-1.1386163266404463,3.4980627988325437,0.19301386899346543,0.01126068031324202,-0.2123673195994045,1.6287336796515217,-0.1424888753229872,1.6287336796515217,-1.9474917631058593,0.06148252180205109,0.6133738705970863,0.7607169539788241,3.0222783212407616,0.06148252180205109,0.11120892157867891,-1.075273613042021,0.6431811538013191,1.179204988513675,1.4915153034770001,0.6431811538013191,1.2722190787348595,-0.005591913085313469,-0.7116898323792509,-0.6536448751928122,-0.4464943548499513,1.179204988513675,0.7896879996375533,-0.1948058268211105,1.2590315225380515,0.1604504658814682,-0.02250118346835699,-0.12517084870498654,-0.373271876429598,-0.24767692023999524,0.5683366593475094,0.30536674022651894,-3.980876334866757,-0.6344483133432426,-5.202277044429628,0.06148252180205109,-0.12517084870498654,-1.1599171531024435,0.9741576934609325,-0.1948058268211105,-0.4835161673691688,-1.289746149293953,-0.4280869276823581,0.07811250742307049,0.30536674022651894,2.7583811399319984,-0.6536448751928122,0.5833929390939195,1.798428045397234,0.1604504658814682,3.0318170762153325,2.2994483251380298,-0.2832385860448953,-0.35513411913799386,2.189571052524327,-0.5208177336190014,-0.12517084870498654,0.09468784334280253,-0.31905629408571334,0.02805701137235168,2.0090196896501236,-0.3914762369552328,0.02805701137235168,-1.1599171531024435,1.07084676596474,-0.992089953515064,-0.9510285615071858,-1.9474917631058593,-0.26542599868242417,0.01126068031324202,-0.12517084870498654,-0.15986707294579158,-0.4835161673691688,-0.7507725016906376,0.3527680424371989,-0.8298890333091614,-0.10791253841717666,0.2894676887918951,-0.1773059016141884,0.09468784334280253,-1.0335027512907717,-1.445808727840182,-0.6344483133432426,-0.4649705794159142,0.5984052493734849,-0.2832385860448953,-0.1424888753229872,0.3997325317718629,-0.6536448751928122,0.36847097049977656,-0.6922649775615227,1.0296274822176772,-0.07357327446040215,1.7625145060761207,1.5167285531774126,0.7022834886797121,-0.07357327446040215,-1.2460779206914567,0.30536674022651894,-0.9103121062691136,-0.31905629408571334,1.8103460646896083,-0.4280869276823581,-0.6922649775615227,-0.7507725016906376,0.43080383738421585,0.65802036299361,0.3997325317718629,-0.10791253841717666,-0.6536448751928122,-0.005591913085313469,-0.24767692023999524
| 3,430
|
Endoplasmic reticulum lumen
| 27
| 61
| 3.557578
| 0.000374
|
Q14257,O15460,Q6P179,Q32P28,O14975,P14625,Q9NWM8,O43681,O95881,Q9Y680,Q9NZ08,P13674,Q969H8,O43852,Q9BTY2,P05067,O75718,Q13438,O00584,P27824,Q9UBS4,O76024,Q96AY3,O60568,Q08431,Q02818,Q07065
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
133,398,407,34,424,300,179,553,436,56,185,314,716,321,202,205,89,596,467,725,750,477,357,376,503,246,253
|
467,2816,424,398,553,321,376,89,477,436,205,1284,1953,3162,1255,2323,314,1536,300,983,2619,3328,3048,3064,725,2800,1959,2641,965,2002,246,253,503,1335,596,133,1202,2236,1373,34,1375,407,1723,1621,1153,1266,2055,827,716,357,1499,1628,1087,202,179,1556,185,750,761,2405,56
|
0.9462000577616902,-0.7704316844994457,1.04340337414266,1.1117439633053623,0.7896879996375533,1.2853737321434007,1.1657819605638418,2.2994483251380298,0.9321647887240839,1.0158151806848401,1.6777690135569574,0.14408985151272588,-0.2123673195994045,-1.1599171531024435,0.1604504658814682,-0.3914762369552328,1.311585046538852,-0.005591913085313469,1.3506596827179598,0.33701658189477507,-0.6153265492951593,-1.6543045466896755,-0.992089953515064,-1.0127520150653435,0.5984052493734849,-0.7507725016906376,-0.2123673195994045,-0.6344483133432426,0.3527680424371989,-0.22999085661134913,1.5167285531774126,1.4915153034770001,0.8898304908049921,0.11120892157867891,0.7315827923762055,2.0204818903795823,0.19301386899346543,-0.33706243340680064,0.09468784334280253,3.0318170762153325,0.09468784334280253,1.0845146796370766,-0.0907134950668146,-0.03946755021715677,0.22536929144369766,0.1604504658814682,-0.24767692023999524,0.47705956297724367,0.6133738705970863,1.2192696206606266,0.02805701137235168,-0.03946755021715677,0.2735187641595761,1.7142527679704935,1.798428045397234,-0.005591913085313469,1.774512395985724,0.5833929390939195,0.5683366593475094,-0.4280869276823581,2.606176282501621
| 3,430
|
Hydrolase activity acting on glycosyl bonds
| 13
| 30
| 3.535286
| 0.000407
|
P17900,O60476,Q9BTY2,P16278,O75503,P06865,P06280,O60502,P54802,P10253,P08236,Q9NUJ1,P04062
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
66,227,202,43,104,268,275,147,87,311,279,221,30
|
977,2797,227,147,104,30,895,275,268,1358,279,311,2856,2549,43,66,2771,774,1224,87,741,1646,1202,551,2957,2756,340,202,221,2712
|
0.33701658189477507,-0.7507725016906376,1.5916594876052144,1.904751655596212,2.189571052524327,3.0603364192521147,0.41529180787632924,1.4151493408700357,1.4279535786684734,0.09468784334280253,1.402314093228658,1.3246420617522143,-0.8099892376198776,-0.558403728184664,2.9065277890482055,2.4918352621956807,-0.7311921139115007,0.5380910558331444,0.17675834803240076,2.321161071650228,0.5833929390939195,-0.0564914375226667,0.19301386899346543,0.8041129767098191,-0.8900812583352817,-0.7116898323792509,1.2590315225380515,1.7142527679704935,1.6287336796515217,-0.6729168790091554
| 3,430
|
Peptide binding
| 22
| 80
| 3.528975
| 0.000417
|
P24390,Q9UIQ6,P10321,O00264,Q15392,O14773,Q8WTV0,Q9NZ08,Q9Y287,P42892,O60684,Q92973,Q03519,Q03518,Q9BYT8,O43731,Q9NQX7,P55899,P01889,P04439,P52294,Q9Y584
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
6,137,393,143,23,162,169,185,190,69,198,208,215,218,349,97,225,111,369,244,117,119
|
1848,143,1248,1908,1116,2796,162,2348,1635,926,2921,97,198,1098,369,244,1285,3126,3233,393,2148,2353,3328,6,3064,2640,2598,1317,965,657,2642,739,69,2952,3282,1915,862,2079,966,117,1033,575,111,2862,1014,2702,2804,218,215,3194,1578,2839,1922,2704,1372,3183,900,23,407,970,169,208,1460,1270,2166,1085,2912,349,849,474,225,1277,185,1053,2571,137,3079,190,3043,119
|
-0.15986707294579158,1.9513415899455118,0.1604504658814682,-0.1948058268211105,0.24146991514915547,-0.7507725016906376,1.8577557582221775,-0.40974773902190176,-0.0564914375226667,0.3841256925736641,-0.8699343008139493,2.233787760016152,1.7263589960332117,0.25751962221115077,1.179204988513675,1.5292904957224467,0.14408985151272588,-1.096295452188383,-1.3117306703903504,1.125305736257329,-0.30111518243997987,-0.40974773902190176,-1.6543045466896755,3.713359366894026,-1.0127520150653435,-0.6344483133432426,-0.596278947334594,0.1276761298241045,0.3527680424371989,0.65802036299361,-0.6344483133432426,0.5833929390939195,2.4496613605694386,-0.8900812583352817,-1.468526945815869,-0.1948058268211105,0.44626893355334946,-0.26542599868242417,0.3527680424371989,2.1113172784145564,0.30536674022651894,0.7607169539788241,2.1784605959005607,-0.8099892376198776,0.32121625895525563,-0.6729168790091554,-0.7507725016906376,1.6287336796515217,1.641034754600386,-1.2028041638743916,-0.02250118346835699,-0.7901703605422196,-0.1948058268211105,-0.6729168790091554,0.09468784334280253,-1.1813127889529935,0.41529180787632924,3.1543688124281597,1.0845146796370766,0.3527680424371989,1.8459424393187207,1.6777690135569574,0.04479749007284595,0.1604504658814682,-0.30111518243997987,0.2735187641595761,-0.8498704751461239,1.2458108826688405,0.4616874064468927,0.9462000577616902,1.6164042064007391,0.1604504658814682,1.774512395985724,0.30536674022651894,-0.558403728184664,1.9975331678372859,-1.0127520150653435,1.7625145060761207,-0.971515740451046,2.1113172784145564
| 3,430
|
Glycoprotein biosynthetic process
| 25
| 55
| 3.525036
| 0.000423
|
Q7LGA3,O14734,O60512,O60502,Q9H0U3,Q2TAA5,Q16706,Q8N4A0,P46977,Q9Y287,Q86YN1,Q10472,Q9UL01,Q96L58,Q9NQX7,Q92542,O60476,O60762,Q6ZXV5,Q9BT22,P04844,O15118,Q8NAT1,P35610,O60568
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
128,391,18,147,536,288,551,172,430,190,453,456,79,339,225,612,227,605,233,494,362,109,115,252,376
|
2107,391,109,2767,752,837,227,147,18,376,2546,605,2220,1356,2743,872,362,1190,252,2228,430,2836,2484,1296,2608,914,875,456,1646,1484,551,288,233,128,1723,453,172,115,628,612,2849,339,494,536,1138,748,3424,850,225,1246,1556,2687,79,190,1698
|
-0.2832385860448953,1.125305736257329,2.1784605959005607,-0.7311921139115007,0.5683366593475094,0.4616874064468927,1.5916594876052144,1.904751655596212,3.237676205824806,1.1657819605638418,-0.558403728184664,0.7169539114401163,-0.33706243340680064,0.09468784334280253,-0.7116898323792509,0.43080383738421585,1.1925938145223307,0.19301386899346543,1.4915153034770001,-0.33706243340680064,1.0296274822176772,-0.7901703605422196,-0.5021316919187672,0.14408985151272588,-0.596278947334594,0.3997325317718629,0.43080383738421585,0.9741576934609325,-0.0564914375226667,0.02805701137235168,0.8041129767098191,1.3894476706931538,1.5792439505261,2.0547236877093185,-0.0907134950668146,0.98808050071691,1.8341031346457968,2.156171440265243,0.7022834886797121,0.7169539114401163,-0.7901703605422196,1.2590315225380515,0.9180915884762,0.8328430643605732,0.24146991514915547,0.5833929390939195,-4.1411192303358,0.4616874064468927,1.6164042064007391,0.17675834803240076,-0.005591913085313469,-0.6536448751928122,2.3750691920218543,1.7625145060761207,-0.07357327446040215
| 3,430
|
Protein targeting to mitochondrion
| 16
| 46
| 3.498238
| 0.000468
|
P30536,Q99797,Q9Y5J9,Q10713,O14737,Q8TB36,Q9NS69,Q8N4H5,O14925,Q99595,O60830,Q9Y512,Q5JRX3,Q9Y584,Q9Y5L4,Q9P0J0
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
2,290,193,292,165,390,7,101,204,78,20,278,85,119,125,158
|
2173,165,204,565,20,1532,1098,2898,803,3286,414,1443,656,3180,2260,2,3218,677,2040,694,575,2673,292,900,3016,968,951,85,1795,101,390,885,78,290,889,1867,7,158,3307,1114,3222,278,119,571,193,125
|
-0.31905629408571334,1.8459424393187207,1.6777690135569574,0.7752227411673067,3.2100435371001237,-0.005591913085313469,0.25751962221115077,-0.8498704751461239,0.4923857069491886,-1.4913543909405875,1.07084676596474,0.04479749007284595,0.65802036299361,-1.1813127889529935,-0.35513411913799386,3.92901774642917,-1.267862233870033,0.6431811538013191,-0.24767692023999524,0.6282990804246098,0.7607169539788241,-0.6536448751928122,1.3765499068522848,0.41529180787632924,-0.9510285615071858,0.3527680424371989,0.36847097049977656,2.3319852246797077,-0.12517084870498654,2.211724229893288,1.1388325289942267,0.43080383738421585,2.3750691920218543,1.3894476706931538,0.43080383738421585,-0.15986707294579158,3.602417135580486,1.8813049364421908,-1.5373416114687155,0.25751962221115077,-1.267862233870033,1.4151493408700357,2.1113172784145564,0.7752227411673067,1.750489731196436,2.066089721766653
| 3,430
|
Tetrapyrrole binding
| 14
| 18
| 3.492956
| 0.000478
|
Q8WUJ1,O15173,P53701,P08574,P30519,O43169,O00264,Q9Y5Z4,Q16850,Q9H7Z7,Q99707,Q96EY8,P09601,Q6UW02
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
129,99,167,296,44,14,143,50,210,474,284,442,59,384
|
143,99,14,296,59,1665,44,167,210,384,525,129,442,284,474,1501,3043,50
|
1.9513415899455118,2.211724229893288,3.3468758304359083,1.3636206339195902,2.54410242985927,-0.07357327446040215,2.8378826071016987,1.8459424393187207,1.6655522802639968,1.1523245386286525,0.861414936766202,2.0547236877093185,1.0158151806848401,1.402314093228658,0.9462000577616902,0.02805701137235168,-0.971515740451046,2.68787200548125
| 3,430
|
oxidoreductase
| 19
| 43
| 3.492629
| 0.000478
|
P51970,O43169,Q8N0U8,O95168,O43676,Q6DKJ4,Q16134,O14949,O15254,P00403,O95831,O75306,Q86Y39,Q15067,Q9Y6M9,P16435,O96000,Q8N4Q0,Q08431
|
Functions
|
Panther Protein class
|
panther_protein_class
|
386,14,17,529,21,406,533,155,285,28,414,413,168,319,326,231,606,492,503
|
892,1950,155,285,14,1311,21,2922,413,978,529,3008,414,606,28,3161,1568,3028,231,1997,1998,2356,3168,2359,3152,386,1513,2268,503,2297,319,533,3131,1673,1971,406,168,17,492,1499,1837,642,326
|
0.41529180787632924,-0.2123673195994045,1.8813049364421908,1.3894476706931538,3.3468758304359083,0.1276761298241045,3.200802504118346,-0.8699343008139493,1.07084676596474,0.33701658189477507,0.8471486580863727,-0.9510285615071858,1.07084676596474,0.7169539114401163,3.0698107589013315,-1.1599171531024435,-0.02250118346835699,-0.971515740451046,1.5792439505261,-0.22999085661134913,-0.22999085661134913,-0.40974773902190176,-1.1599171531024435,-0.40974773902190176,-1.1386163266404463,1.1388325289942267,0.01126068031324202,-0.35513411913799386,0.8898304908049921,-0.373271876429598,1.2984956621256847,0.8328430643605732,-1.096295452188383,-0.07357327446040215,-0.2123673195994045,1.0845146796370766,1.8459424393187207,3.256023162941908,0.9180915884762,0.02805701137235168,-0.1424888753229872,0.6875712647067221,1.2853737321434007
| 3,430
|
Protein localization to mitochondrion
| 22
| 59
| 3.490735
| 0.000482
|
P30536,P52789,Q8TB36,Q9NS69,Q9Y6C9,O60830,Q9Y512,Q9P0J0,O95831,Q99797,Q10713,O14737,Q15070,Q9Y5J7,O43615,Q9Y5J9,O14925,Q99595,Q5JRX3,Q8N4H5,Q9Y584,Q9Y5L4
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
2,510,390,7,145,20,278,158,414,290,292,165,181,571,565,193,204,78,85,101,119,125
|
2173,2026,1559,165,204,565,20,1532,1098,2898,803,3286,414,1443,656,2965,3180,982,1880,2260,2505,2,1999,3218,677,2040,694,510,575,2673,988,292,181,900,3016,968,951,85,1795,101,390,1236,885,78,290,889,1867,7,158,3307,1114,1350,3222,278,119,571,193,125,145
|
-0.31905629408571334,-0.24767692023999524,-0.02250118346835699,1.8459424393187207,1.6777690135569574,0.7752227411673067,3.2100435371001237,-0.005591913085313469,0.25751962221115077,-0.8498704751461239,0.4923857069491886,-1.4913543909405875,1.07084676596474,0.04479749007284595,0.65802036299361,-0.9103121062691136,-1.1813127889529935,0.33701658189477507,-0.1773059016141884,-0.35513411913799386,-0.5208177336190014,3.92901774642917,-0.22999085661134913,-1.267862233870033,0.6431811538013191,-0.24767692023999524,0.6282990804246098,0.8756421363992508,0.7607169539788241,-0.6536448751928122,0.33701658189477507,1.3765499068522848,1.7864835322979642,0.41529180787632924,-0.9510285615071858,0.3527680424371989,0.36847097049977656,2.3319852246797077,-0.12517084870498654,2.211724229893288,1.1388325289942267,0.17675834803240076,0.43080383738421585,2.3750691920218543,1.3894476706931538,0.43080383738421585,-0.15986707294579158,3.602417135580486,1.8813049364421908,-1.5373416114687155,0.25751962221115077,0.11120892157867891,-1.267862233870033,1.4151493408700357,2.1113172784145564,0.7752227411673067,1.750489731196436,2.066089721766653,1.9397317456196084
| 3,430
|
Intrinsic component of mitochondrial membrane
| 22
| 43
| 3.486659
| 0.000489
|
Q8TB36,Q9Y2R0,O60830,Q9Y512,Q16134,Q96NB2,Q9H9P8,Q15070,Q13505,Q6UXV4,O14925,Q99595,Q9NX63,Q00325,P12235,Q9NVH1,Q9UG56,Q9BUR5,Q16891,Q6P4A7,P57105,Q5XKP0
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
390,19,20,278,533,410,688,181,58,697,204,78,732,214,213,616,487,613,479,232,238,626
|
204,1142,20,1010,1029,1098,839,1443,213,3050,1163,1058,238,214,58,181,900,533,479,951,626,232,697,756,1521,997,1130,390,410,78,613,887,3002,942,688,2445,616,732,487,3398,19,1025,278
|
1.6777690135569574,0.22536929144369766,3.2100435371001237,0.32121625895525563,0.30536674022651894,0.25751962221115077,0.4616874064468927,0.04479749007284595,1.641034754600386,-0.992089953515064,0.20921739577808898,0.2894676887918951,1.554325783520826,1.641034754600386,2.5544966637542177,1.7864835322979642,0.41529180787632924,0.8328430643605732,0.9321647887240839,0.36847097049977656,0.7022834886797121,1.5792439505261,0.6282990804246098,0.5683366593475094,0.01126068031324202,0.33701658189477507,0.24146991514915547,1.1388325289942267,1.0845146796370766,2.3750691920218543,0.7169539114401163,0.43080383738421585,-0.9306276139125141,0.3841256925736641,0.6431811538013191,-0.4649705794159142,0.7169539114401163,0.5984052493734849,0.9321647887240839,-2.2874512966961964,3.2192694624153164,0.32121625895525563,1.4151493408700357
| 3,430
|
Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen
| 14
| 34
| 3.478088
| 0.000505
|
Q32P28,Q9NVH6,Q14534,P16435,Q15800,P30519,O15460,Q16850,O75845,Q8NB78,P13674,P09601,O60568,Q6UW02
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
34,197,122,231,88,44,398,210,470,184,314,59,376,384
|
2107,644,398,2663,376,1636,782,470,554,1284,59,314,231,841,44,2266,1296,2087,122,88,210,34,2754,1650,384,2787,2653,1547,2885,184,473,1942,197,2591
|
-0.2832385860448953,0.6728169776242082,1.1117439633053623,-0.6536448751928122,1.1657819605638418,-0.0564914375226667,0.522901157152449,0.9462000577616902,0.7896879996375533,0.14408985151272588,2.54410242985927,1.311585046538852,1.5792439505261,0.4616874064468927,2.8378826071016987,-0.35513411913799386,0.14408985151272588,-0.26542599868242417,2.077431989617715,2.310315469590055,1.6655522802639968,3.0318170762153325,-0.7116898323792509,-0.0564914375226667,1.1523245386286525,-0.7311921139115007,-0.6344483133432426,-0.005591913085313469,-0.8298890333091614,1.774512395985724,0.9462000577616902,-0.1948058268211105,1.738437938975464,-0.5773048800496771
| 3,430
|
Optic disc pallor
| 20
| 50
| 3.476971
| 0.000507
|
Q9H061,Q96CU9,P51798,Q92974,O43676,O95831,O75306,Q10713,Q86Y39,Q13277,Q9Y287,Q9Y6M9,Q9NPL8,P03886,Q96L58,Q6P4Q7,Q9UG56,O96000,P04439,O60313
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
12,274,524,526,21,414,413,292,168,427,190,326,325,73,339,598,487,606,244,375
|
892,1559,977,2816,604,1328,21,961,375,1441,413,978,1532,1442,1638,414,606,73,244,2878,1880,2639,3031,3152,524,3360,292,427,598,1171,168,1681,1493,998,935,2057,526,274,339,792,2518,1212,12,1136,325,749,487,190,1025,326
|
0.41529180787632924,-0.02250118346835699,0.33701658189477507,-0.7704316844994457,0.7169539114401163,0.11120892157867891,3.200802504118346,0.3527680424371989,1.1657819605638418,0.04479749007284595,1.07084676596474,0.33701658189477507,-0.005591913085313469,0.04479749007284595,-0.0564914375226667,1.07084676596474,0.7169539114401163,2.4178172840822203,1.5292904957224467,-0.8298890333091614,-0.1773059016141884,-0.6344483133432426,-0.971515740451046,-1.1386163266404463,0.861414936766202,-1.8477085071425041,1.3765499068522848,1.04340337414266,0.7315827923762055,0.20921739577808898,1.8459424393187207,-0.07357327446040215,0.02805701137235168,0.33701658189477507,0.3841256925736641,-0.24767692023999524,0.861414936766202,1.4279535786684734,1.2590315225380515,0.522901157152449,-0.5208177336190014,0.19301386899346543,3.4362955117330025,0.24146991514915547,1.2853737321434007,0.5833929390939195,0.9321647887240839,1.7625145060761207,0.32121625895525563,1.2853737321434007
| 3,430
|
Steroid binding
| 16
| 23
| 3.475777
| 0.000509
|
P30536,O15173,Q9BZF1,P61916,P38435,P21796,Q96SU4,O00264,P45880,O15118,P35610,P22059,O75477,Q14849,Q14108,P04062
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
2,99,458,512,136,9,564,143,15,109,252,316,566,27,60,30
|
143,109,99,566,2070,30,607,2146,9,316,2261,2,252,136,15,512,60,27,564,1591,1553,458,3380
|
1.9513415899455118,2.1784605959005607,2.211724229893288,0.7752227411673067,-0.26542599868242417,3.0603364192521147,0.7169539114401163,-0.30111518243997987,3.489279818123242,1.2984956621256847,-0.35513411913799386,3.92901774642917,1.4915153034770001,1.9975331678372859,3.2925394092933984,0.8756421363992508,2.5336885717746562,3.0792691433168833,0.7896879996375533,-0.02250118346835699,-0.005591913085313469,0.9741576934609325,-2.049460345691425
| 3,430
|
Protein targeting
| 38
| 118
| 3.470107
| 0.00052
|
P46379,P30536,Q8TB36,Q9NS69,O00560,O60830,Q9Y512,Q9UGP8,Q9P0J0,O95831,Q99797,P43307,O14737,Q10713,Q7Z3B4,O43681,Q9Y5J7,Q14108,O43615,O60725,Q9Y5J9,P55786,O14925,Q99595,Q5JRX3,Q99523,Q13438,Q16543,Q8N4H5,Q96RL7,P46934,Q9Y5M8,P13473,P57105,Q9NQG6,Q15629,Q9Y584,Q9Y5L4
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
256,2,390,7,266,20,278,547,158,414,290,36,165,292,559,553,571,60,565,65,193,575,204,78,85,600,596,229,101,358,103,236,237,238,499,116,119,125
|
1737,2173,2026,266,2347,165,204,907,565,553,1809,65,20,1056,1532,2069,1098,2898,803,3286,414,1443,656,1508,3180,2108,237,2260,1147,2458,3217,774,2,3293,2774,3218,2642,739,36,256,103,677,2184,2040,2079,1364,694,575,238,3390,2930,2862,1014,3034,2555,2902,2645,2673,2464,292,1716,1422,596,60,877,713,900,116,3016,229,968,951,85,2335,2393,1586,559,2868,1795,2275,2160,2678,101,390,2468,358,2760,793,885,600,1272,78,290,1839,889,3003,1867,499,7,2400,158,3307,547,1053,2687,1114,1386,1845,3042,617,3222,2404,278,119,571,193,125,236
|
-0.10791253841717666,-0.31905629408571334,-0.24767692023999524,1.4407269703301229,-0.40974773902190176,1.8459424393187207,1.6777690135569574,0.3997325317718629,0.7752227411673067,0.7896879996375533,-0.1424888753229872,2.4918352621956807,3.2100435371001237,0.2894676887918951,-0.005591913085313469,-0.26542599868242417,0.25751962221115077,-0.8498704751461239,0.4923857069491886,-1.4913543909405875,1.07084676596474,0.04479749007284595,0.65802036299361,0.01126068031324202,-1.1813127889529935,-0.2832385860448953,1.554325783520826,-0.35513411913799386,0.22536929144369766,-0.4835161673691688,-1.267862233870033,0.5380910558331444,3.92901774642917,-1.5142922206614813,-0.7311921139115007,-1.267862233870033,-0.6344483133432426,0.5833929390939195,3.0222783212407616,1.47886368568901,2.2006588969869694,0.6431811538013191,-0.31905629408571334,-0.24767692023999524,-0.26542599868242417,0.09468784334280253,0.6282990804246098,0.7607169539788241,1.554325783520826,-2.153721952328721,-0.8699343008139493,-0.8099892376198776,0.32121625895525563,-0.971515740451046,-0.558403728184664,-0.8498704751461239,-0.6344483133432426,-0.6536448751928122,-0.4835161673691688,1.3765499068522848,-0.0907134950668146,0.06148252180205109,0.7315827923762055,2.5336885717746562,0.43080383738421585,0.6133738705970863,0.41529180787632924,2.133790611209967,-0.9510285615071858,1.5916594876052144,0.3527680424371989,0.36847097049977656,2.3319852246797077,-0.3914762369552328,-0.4280869276823581,-0.02250118346835699,0.7896879996375533,-0.8099892376198776,-0.12517084870498654,-0.35513411913799386,-0.30111518243997987,-0.6536448751928122,2.211724229893288,1.1388325289942267,-0.4835161673691688,1.2192696206606266,-0.7116898323792509,0.522901157152449,0.43080383738421585,0.7315827923762055,0.1604504658814682,2.3750691920218543,1.3894476706931538,-0.1424888753229872,0.43080383738421585,-0.9306276139125141,-0.15986707294579158,0.903980231650309,3.602417135580486,-0.4280869276823581,1.8813049364421908,-1.5373416114687155,0.8184979173823138,0.30536674022651894,-0.6536448751928122,0.25751962221115077,0.09468784334280253,-0.1424888753229872,-0.971515740451046,0.7169539114401163,-1.267862233870033,-0.4280869276823581,1.4151493408700357,2.1113172784145564,0.7752227411673067,1.750489731196436,2.066089721766653,1.5667994320520733
| 3,430
|
Increased serum lactate
| 28
| 107
| 3.465405
| 0.000529
|
P51970,Q9NP80,Q96CU9,Q9UBX3,Q70HW3,O14949,P00403,Q9P0J0,O95831,O75306,Q99797,Q86Y39,P08574,Q9BWD1,Q9NWS8,Q9NVI7,Q9Y6M9,O75648,P03886,P13073,Q5JRX3,Q00325,P12235,Q9BW92,Q6P4A7,P14854,Q9Y584,P35610
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
386,264,274,13,16,155,28,158,414,413,290,168,296,304,182,443,326,444,73,336,85,214,213,485,232,363,119,252
|
892,1948,1559,1950,155,2922,1142,1441,413,1532,1442,444,1029,2033,414,1951,28,2224,73,1566,2035,296,723,1568,3415,213,336,363,3331,2639,1119,693,984,2354,3031,3011,1747,252,2926,804,2801,1395,2507,2602,3152,2509,386,2669,2483,1713,2462,1034,1576,1333,214,1450,1015,742,2995,1673,968,951,651,85,1262,810,680,626,2786,232,1104,16,525,1424,168,746,1493,3355,920,2565,1459,274,1865,937,1837,290,2518,485,304,1179,816,1660,1089,264,443,1091,182,2133,158,13,1350,488,2024,1531,119,1601,326
|
0.41529180787632924,-0.2123673195994045,-0.02250118346835699,-0.2123673195994045,1.8813049364421908,-0.8699343008139493,0.22536929144369766,0.04479749007284595,1.07084676596474,-0.005591913085313469,0.04479749007284595,1.001966258000303,0.30536674022651894,-0.24767692023999524,1.07084676596474,-0.2123673195994045,3.0698107589013315,-0.33706243340680064,2.4178172840822203,-0.02250118346835699,-0.24767692023999524,1.3636206339195902,0.5984052493734849,-0.02250118346835699,-3.285316956235847,1.641034754600386,1.2590315225380515,1.1925938145223307,-1.6780491319681583,-0.6344483133432426,0.24146991514915547,0.6282990804246098,0.33701658189477507,-0.40974773902190176,-0.971515740451046,-0.9510285615071858,-0.10791253841717666,1.4915153034770001,-0.8699343008139493,0.4923857069491886,-0.7507725016906376,0.07811250742307049,-0.5208177336190014,-0.596278947334594,-1.1386163266404463,-0.5208177336190014,1.1388325289942267,-0.6536448751928122,-0.5021316919187672,-0.0907134950668146,-0.4835161673691688,0.30536674022651894,-0.02250118346835699,0.11120892157867891,1.641034754600386,0.04479749007284595,0.32121625895525563,0.5833929390939195,-0.9306276139125141,-0.07357327446040215,0.3527680424371989,0.36847097049977656,0.6728169776242082,2.3319852246797077,0.1604504658814682,0.4923857069491886,0.6431811538013191,0.7022834886797121,-0.7311921139115007,1.5792439505261,0.25751962221115077,3.2651743542921823,0.861414936766202,0.06148252180205109,1.8459424393187207,0.5833929390939195,0.02805701137235168,-1.8230922651443087,0.3997325317718629,-0.558403728184664,0.04479749007284595,1.4279535786684734,-0.15986707294579158,0.3841256925736641,-0.1424888753229872,1.3894476706931538,-0.5208177336190014,0.9321647887240839,1.3506596827179598,0.20921739577808898,0.4923857069491886,-0.0564914375226667,0.2735187641595761,1.4534696782308594,1.0158151806848401,0.2735187641595761,1.7864835322979642,-0.2832385860448953,1.8813049364421908,3.391761695054266,0.11120892157867891,0.9321647887240839,-0.22999085661134913,0.01126068031324202,2.1113172784145564,-0.02250118346835699,1.2853737321434007
| 3,430
|
Abnormal vascular physiology
| 17
| 56
| 3.460255
| 0.00054
|
O75844,P51970,O14678,P03886,P05067,P14854,P01889,Q14739,P06280,Q9NWM8,Q8IZA0,O60568,Q9Y4P3,Q9NZ08,Q14108,P00403,P04062
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
32,386,257,73,205,363,369,222,275,179,93,376,313,185,60,28,30
|
1389,257,398,2350,376,2145,3248,32,1390,606,28,369,1534,73,30,1877,205,275,1255,363,1956,1119,3127,2073,2925,3064,3066,1190,2775,2000,1541,796,1612,524,386,1290,2879,1296,60,3275,222,2299,680,822,953,2676,580,93,1624,2132,179,185,866,2025,313,3043
|
0.07811250742307049,1.4661818634308703,1.1117439633053623,-0.40974773902190176,1.1657819605638418,-0.30111518243997987,-1.3560056220962575,3.050846065270086,0.07811250742307049,0.7169539114401163,3.0698107589013315,1.179204988513675,-0.005591913085313469,2.4178172840822203,3.0603364192521147,-0.1773059016141884,1.6777690135569574,1.4151493408700357,0.1604504658814682,1.1925938145223307,-0.2123673195994045,0.24146991514915547,-1.096295452188383,-0.26542599868242417,-0.8699343008139493,-1.0127520150653435,-1.0127520150653435,0.19301386899346543,-0.7311921139115007,-0.22999085661134913,-0.005591913085313469,0.5076661391022604,-0.03946755021715677,0.861414936766202,1.1388325289942267,0.14408985151272588,-0.8298890333091614,0.14408985151272588,2.5336885717746562,-1.445808727840182,1.6164042064007391,-0.373271876429598,0.6431811538013191,0.47705956297724367,0.36847097049977656,-0.6536448751928122,0.7607169539788241,2.2667166943530197,-0.03946755021715677,-0.2832385860448953,1.798428045397234,1.774512395985724,0.44626893355334946,-0.22999085661134913,1.3246420617522143,-0.971515740451046
| 3,430
|
Mitochondrial substrate/solute carrier [IPR018108]
| 17
| 20
| 3.45721
| 0.000546
|
Q6NUK1,O75746,P12236,Q02978,O43808,Q9UBX3,Q9Y619,Q9NZJ7,Q70HW3,Q9Y6C9,Q9H2D1,Q9UJS0,Q9BSK2,Q00325,O43772,Q9BQT8,P12235
|
Sequence
|
InterPro Repeat
|
interpro_repeat
|
580,692,418,696,573,13,45,341,16,145,49,708,61,214,468,157,213
|
468,573,692,736,213,418,1100,214,696,580,16,157,61,49,1409,341,13,708,45,145
|
0.9462000577616902,0.7607169539788241,0.6282990804246098,0.5833929390939195,1.641034754600386,1.057143066123191,0.25751962221115077,1.641034754600386,0.6282990804246098,0.7607169539788241,3.2651743542921823,1.8813049364421908,2.5336885717746562,2.7383268943293446,0.07811250742307049,1.2590315225380515,3.391761695054266,0.6282990804246098,2.7982738550861823,1.9397317456196084
| 3,430
|
Mitochondrial carrier domain superfamily [IPR023395]
| 17
| 20
| 3.45721
| 0.000546
|
Q6NUK1,O75746,P12236,Q02978,O43808,Q9UBX3,Q9Y619,Q9NZJ7,Q70HW3,Q9Y6C9,Q9H2D1,Q9UJS0,Q9BSK2,Q00325,O43772,Q9BQT8,P12235
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
580,692,418,696,573,13,45,341,16,145,49,708,61,214,468,157,213
|
468,573,692,736,213,418,1100,214,696,580,16,157,61,49,1409,341,13,708,45,145
|
0.9462000577616902,0.7607169539788241,0.6282990804246098,0.5833929390939195,1.641034754600386,1.057143066123191,0.25751962221115077,1.641034754600386,0.6282990804246098,0.7607169539788241,3.2651743542921823,1.8813049364421908,2.5336885717746562,2.7383268943293446,0.07811250742307049,1.2590315225380515,3.391761695054266,0.6282990804246098,2.7982738550861823,1.9397317456196084
| 3,430
|
SLC25 family of mitochondrial transporters
| 17
| 20
| 3.45721
| 0.000546
|
Q6NUK1,O75746,P12236,Q02978,O43808,Q9UBX3,Q9Y619,Q9NZJ7,Q70HW3,Q9Y6C9,Q9H2D1,Q9UJS0,Q9BSK2,Q00325,O43772,Q9BQT8,P12235
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
580,692,418,696,573,13,45,341,16,145,49,708,61,214,468,157,213
|
468,573,692,736,213,418,1100,214,696,580,16,157,61,49,1409,341,13,708,45,145
|
0.9462000577616902,0.7607169539788241,0.6282990804246098,0.5833929390939195,1.641034754600386,1.057143066123191,0.25751962221115077,1.641034754600386,0.6282990804246098,0.7607169539788241,3.2651743542921823,1.8813049364421908,2.5336885717746562,2.7383268943293446,0.07811250742307049,1.2590315225380515,3.391761695054266,0.6282990804246098,2.7982738550861823,1.9397317456196084
| 3,430
|
Abnormality of the cerebrospinal fluid
| 45
| 157
| 3.454152
| 0.000552
|
P51970,P51798,Q7KZN9,Q96CU9,O43676,O95202,Q15392,P21964,P08236,P00403,Q9P0J0,P04062,O95831,P23786,O75306,Q10713,Q12768,P07602,P53701,Q86Y39,O43681,Q9NWS8,Q15427,Q6NUK1,Q9Y6M9,Q9NPL8,P55011,P03886,O15360,Q9NZJ7,Q99519,Q96L58,P13073,O96028,Q16625,Q8TAA9,Q00839,O96000,P16435,P48651,Q9UBM7,P14854,Q8NAT1,Q9NR77,Q14738
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
386,524,525,274,21,401,23,280,279,28,158,30,414,33,413,292,550,38,167,168,553,182,312,580,326,325,574,73,454,341,340,339,336,334,346,482,609,606,231,360,632,363,115,123,254
|
1472,892,1948,1437,1950,977,1438,869,454,1774,752,21,2922,553,1142,1055,1097,1473,1441,413,2410,978,1442,3248,3149,2897,401,2033,414,606,334,28,73,30,1877,1284,38,1953,279,2035,1189,676,336,363,983,231,896,2639,1415,1446,3127,2073,280,33,1851,3031,2576,3011,795,1747,1813,1190,3068,2413,804,2078,739,2801,1395,1541,360,1543,862,3152,2509,524,386,2483,167,2670,574,1290,2780,2992,1333,609,1198,1015,2934,1227,2364,1297,292,2045,550,3296,2626,2113,254,2995,23,312,346,1673,810,822,580,1104,525,1424,994,168,1652,1493,2010,115,3355,920,482,935,2565,1237,2422,2338,1269,1176,1624,274,339,1865,885,340,1837,2518,1242,3121,1942,2735,640,850,3371,325,123,1502,2022,2375,1091,182,341,749,158,632,666,2025,3043,1698,326
|
0.02805701137235168,0.41529180787632924,-0.2123673195994045,0.04479749007284595,-0.2123673195994045,0.33701658189477507,0.04479749007284595,0.43080383738421585,0.9741576934609325,-0.12517084870498654,0.5683366593475094,3.200802504118346,-0.8699343008139493,0.7896879996375533,0.22536929144369766,0.2894676887918951,0.25751962221115077,0.02805701137235168,0.04479749007284595,1.07084676596474,-0.4464943548499513,0.33701658189477507,0.04479749007284595,-1.3560056220962575,-1.1386163266404463,-0.8498704751461239,1.0981470112960925,-0.24767692023999524,1.07084676596474,0.7169539114401163,1.2590315225380515,3.0698107589013315,2.4178172840822203,3.0603364192521147,-0.1773059016141884,0.14408985151272588,3.0127233121243298,-0.2123673195994045,1.402314093228658,-0.24767692023999524,0.19301386899346543,0.6431811538013191,1.2590315225380515,1.1925938145223307,0.33701658189477507,1.5792439505261,0.41529180787632924,-0.6344483133432426,0.06148252180205109,0.04479749007284595,-1.096295452188383,-0.26542599868242417,1.402314093228658,3.0318170762153325,-0.15986707294579158,-0.971515740451046,-0.5773048800496771,-0.9510285615071858,0.5076661391022604,-0.10791253841717666,-0.1424888753229872,0.19301386899346543,-1.0127520150653435,-0.4464943548499513,0.4923857069491886,-0.26542599868242417,0.5833929390939195,-0.7507725016906376,0.07811250742307049,-0.005591913085313469,1.2059486289837344,-0.005591913085313469,0.44626893355334946,-1.1386163266404463,-0.5208177336190014,0.861414936766202,1.1388325289942267,-0.5021316919187672,1.8459424393187207,-0.6536448751928122,0.7607169539788241,0.14408985151272588,-0.7311921139115007,-0.9306276139125141,0.11120892157867891,0.7169539114401163,0.19301386899346543,0.32121625895525563,-0.8699343008139493,0.17675834803240076,-0.40974773902190176,0.14408985151272588,1.3765499068522848,-0.24767692023999524,0.8041129767098191,-1.5142922206614813,-0.6153265492951593,-0.2832385860448953,1.4915153034770001,-0.9306276139125141,3.1543688124281597,1.3246420617522143,1.2458108826688405,-0.07357327446040215,0.4923857069491886,0.47705956297724367,0.7607169539788241,0.25751962221115077,0.861414936766202,0.06148252180205109,0.33701658189477507,1.8459424393187207,-0.0564914375226667,0.02805701137235168,-0.22999085661134913,2.156171440265243,-1.8230922651443087,0.3997325317718629,0.9321647887240839,0.3841256925736641,-0.558403728184664,0.17675834803240076,-0.4464943548499513,-0.3914762369552328,0.1604504658814682,0.20921739577808898,-0.03946755021715677,1.4279535786684734,1.2590315225380515,-0.15986707294579158,0.43080383738421585,1.2590315225380515,-0.1424888753229872,-0.5208177336190014,0.17675834803240076,-1.075273613042021,-0.1948058268211105,-0.6922649775615227,0.6875712647067221,0.4616874064468927,-1.9474917631058593,1.2853737321434007,2.077431989617715,0.02805701137235168,-0.22999085661134913,-0.40974773902190176,0.2735187641595761,1.7864835322979642,1.2590315225380515,0.5833929390939195,1.8813049364421908,0.7022834886797121,0.65802036299361,-0.22999085661134913,-0.971515740451046,-0.07357327446040215,1.2853737321434007
| 3,430
|
Glycosidase
| 10
| 19
| 3.45136
| 0.000558
|
O60476,Q9BTY2,P16278,P06865,P06280,O60502,P54802,P10253,P08236,P04062
|
Functions
|
Protein Atlas Molecular function
|
protein_atlas_molecular_function
|
227,202,43,268,275,147,87,311,279,30
|
977,2797,227,147,30,895,275,268,1358,279,311,43,1224,87,1646,1202,551,340,202
|
0.33701658189477507,-0.7507725016906376,1.5916594876052144,1.904751655596212,3.0603364192521147,0.41529180787632924,1.4151493408700357,1.4279535786684734,0.09468784334280253,1.402314093228658,1.3246420617522143,2.9065277890482055,0.17675834803240076,2.321161071650228,-0.0564914375226667,0.19301386899346543,0.8041129767098191,1.2590315225380515,1.7142527679704935
| 3,430
|
Abnormal esophagus physiology
| 52
| 233
| 3.43336
| 0.000596
|
O75874,O14678,P61916,P48735,Q13045,P51571,P06280,O95202,Q99720,P21964,Q9UGP8,P04062,O75306,O15269,Q12768,P07602,O15270,Q9Y619,Q9Y4P3,Q14108,Q96D71,Q15067,Q6NUK1,P04350,P42858,P55011,P55795,P03886,Q06787,P05067,P15586,Q9NZJ7,Q99519,Q96PU5,O96028,O75569,P12235,Q8IZA0,Q14739,O76024,Q96RL7,P16435,Q6ZXV5,P35637,O15118,P01889,Q9UHX1,Q9Y584,Q96A33,Q13510,Q9NR77,O60313
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
1,257,512,10,531,403,275,401,26,280,547,30,413,286,550,38,295,45,313,60,582,319,580,445,447,574,196,73,203,205,206,341,340,211,334,342,213,93,222,477,358,231,233,235,109,369,118,119,379,250,123,375
|
1472,2026,1559,2346,257,1438,109,286,295,2318,2174,3060,2350,1142,2283,375,1473,2594,870,1875,413,1442,342,1,477,2070,2947,1777,2179,401,1993,1810,1565,2743,1414,334,2618,369,73,30,445,205,275,2819,38,2596,2286,2597,2035,1255,2856,213,1536,206,1743,231,1996,1956,1569,1446,3191,3127,2073,693,280,2355,1393,738,3031,2800,2576,1747,1813,2775,235,657,2413,804,1572,2748,2228,2111,1961,1395,447,585,2749,10,2967,1258,403,2509,1100,2483,2670,2326,1713,821,574,2387,1290,196,1544,512,3034,1815,1366,2879,695,1576,1333,2484,1783,1334,1450,807,3054,1165,3295,2608,2674,203,2045,550,531,2418,2626,250,60,1485,2298,2113,222,2299,319,1821,1078,1126,2905,2440,1673,3108,2676,2725,2051,580,2976,2610,2845,233,1424,1171,824,1897,2563,1064,2274,1796,93,933,1493,2010,1040,2680,2197,2395,1523,1524,2729,2422,2338,1834,1269,1378,379,582,1209,2732,685,2758,211,3158,358,937,2312,885,340,1837,26,2123,2124,1325,1463,2518,1241,904,2279,3231,1180,3188,849,2370,1409,1067,1089,2521,123,1764,1346,1903,1022,2101,2102,341,1092,1529,632,975,955,547,118,866,3097,1598,2139,2066,1216,2024,3213,313,1025,119,45
|
0.02805701137235168,-0.24767692023999524,-0.02250118346835699,-0.40974773902190176,1.4661818634308703,0.04479749007284595,2.1784605959005607,1.3894476706931538,1.3636206339195902,-0.3914762369552328,-0.31905629408571334,-1.0127520150653435,-0.40974773902190176,0.22536929144369766,-0.373271876429598,1.1657819605638418,0.02805701137235168,-0.596278947334594,0.43080383738421585,-0.1773059016141884,1.07084676596474,0.04479749007284595,1.2458108826688405,3.92901774642917,0.9321647887240839,-0.26542599868242417,-0.8900812583352817,-0.12517084870498654,-0.31905629408571334,1.0981470112960925,-0.22999085661134913,-0.1424888753229872,-0.02250118346835699,-0.7116898323792509,0.06148252180205109,1.2590315225380515,-0.6153265492951593,1.179204988513675,2.4178172840822203,3.0603364192521147,1.001966258000303,1.6777690135569574,1.4151493408700357,-0.7704316844994457,3.0127233121243298,-0.596278947334594,-0.373271876429598,-0.596278947334594,-0.24767692023999524,0.1604504658814682,-0.8099892376198776,1.641034754600386,-0.005591913085313469,1.6777690135569574,-0.10791253841717666,1.5792439505261,-0.22999085661134913,-0.2123673195994045,-0.02250118346835699,0.04479749007284595,-1.2028041638743916,-1.096295452188383,-0.26542599868242417,0.6282990804246098,1.402314093228658,-0.40974773902190176,0.07811250742307049,0.5833929390939195,-0.971515740451046,-0.7507725016906376,-0.5773048800496771,-0.10791253841717666,-0.1424888753229872,-0.7311921139115007,1.5667994320520733,0.65802036299361,-0.4464943548499513,0.4923857069491886,-0.02250118346835699,-0.7116898323792509,-0.33706243340680064,-0.2832385860448953,-0.2123673195994045,0.07811250742307049,1.001966258000303,0.7461703883999292,-0.7116898323792509,3.454011813127605,-0.9103121062691136,0.1604504658814682,1.0981470112960925,-0.5208177336190014,0.25751962221115077,-0.5021316919187672,-0.6536448751928122,-0.3914762369552328,-0.0907134950668146,0.47705956297724367,0.7607169539788241,-0.4280869276823581,0.14408985151272588,1.738437938975464,-0.005591913085313469,0.8756421363992508,-0.971515740451046,-0.1424888753229872,0.09468784334280253,-0.8298890333091614,0.6282990804246098,-0.02250118346835699,0.11120892157867891,-0.5021316919187672,-0.12517084870498654,0.11120892157867891,0.04479749007284595,0.4923857069491886,-0.992089953515064,0.20921739577808898,-1.5142922206614813,-0.596278947334594,-0.6536448751928122,1.7021191193583658,-0.24767692023999524,0.8041129767098191,0.8471486580863727,-0.4464943548499513,-0.6153265492951593,1.5041368739934033,2.5336885717746562,0.02805701137235168,-0.373271876429598,-0.2832385860448953,1.6164042064007391,-0.373271876429598,1.2984956621256847,-0.1424888753229872,0.2735187641595761,0.24146991514915547,-0.8498704751461239,-0.4649705794159142,-0.07357327446040215,-1.0543430004362901,-0.6536448751928122,-0.6922649775615227,-0.24767692023999524,0.7607169539788241,-0.9103121062691136,-0.596278947334594,-0.7901703605422196,1.5792439505261,0.06148252180205109,0.20921739577808898,0.47705956297724367,-0.1773059016141884,-0.558403728184664,0.2894676887918951,-0.35513411913799386,-0.12517084870498654,2.2667166943530197,0.3841256925736641,0.02805701137235168,-0.22999085661134913,0.30536674022651894,-0.6536448751928122,-0.31905629408571334,-0.4280869276823581,0.01126068031324202,0.01126068031324202,-0.6922649775615227,-0.4464943548499513,-0.3914762369552328,-0.1424888753229872,0.1604504658814682,0.09468784334280253,1.1657819605638418,0.7607169539788241,0.19301386899346543,-0.6922649775615227,0.6431811538013191,-0.7116898323792509,1.6655522802639968,-1.1386163266404463,1.2192696206606266,0.3841256925736641,-0.373271876429598,0.43080383738421585,1.2590315225380515,-0.1424888753229872,3.107549151128594,-0.2832385860448953,-0.2832385860448953,0.1276761298241045,0.04479749007284595,-0.5208177336190014,0.17675834803240076,0.41529180787632924,-0.35513411913799386,-1.289746149293953,0.20921739577808898,-1.1813127889529935,0.4616874064468927,-0.40974773902190176,0.07811250742307049,0.2894676887918951,0.2735187641595761,-0.5208177336190014,2.077431989617715,-0.10791253841717666,0.11120892157867891,-0.1773059016141884,0.32121625895525563,-0.26542599868242417,-0.26542599868242417,1.2590315225380515,0.2735187641595761,0.01126068031324202,0.7022834886797121,0.3527680424371989,0.36847097049977656,0.8184979173823138,2.1113172784145564,0.44626893355334946,-1.0335027512907717,-0.02250118346835699,-0.2832385860448953,-0.24767692023999524,0.19301386899346543,-0.22999085661134913,-1.2460779206914567,1.3246420617522143,0.32121625895525563,2.1113172784145564,2.7982738550861823
| 3,430
|
Endocytic vesicle membrane
| 11
| 40
| 3.431156
| 0.000601
|
Q8WTV0,P10321,P13473,Q9Y487,P01889,Q93050,P04439,Q03519,Q15907,Q03518,Q14108
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
169,393,237,175,369,220,244,215,276,218,60
|
926,1186,2071,1702,369,1314,244,393,646,1509,1994,237,1147,3064,1192,1364,1011,986,2644,1149,1259,2804,1783,1450,218,215,1578,1337,1669,60,1583,2237,276,449,169,220,1270,1272,2875,175
|
0.3841256925736641,0.19301386899346543,-0.26542599868242417,-0.0907134950668146,1.179204988513675,0.1276761298241045,1.5292904957224467,1.125305736257329,0.6728169776242082,0.01126068031324202,-0.22999085661134913,1.554325783520826,0.22536929144369766,-1.0127520150653435,0.19301386899346543,0.09468784334280253,0.32121625895525563,0.33701658189477507,-0.6344483133432426,0.22536929144369766,0.1604504658814682,-0.7507725016906376,-0.12517084870498654,0.04479749007284595,1.6287336796515217,1.641034754600386,-0.02250118346835699,0.11120892157867891,-0.07357327446040215,2.5336885717746562,-0.02250118346835699,-0.33706243340680064,1.4151493408700357,1.001966258000303,1.8459424393187207,1.6287336796515217,0.1604504658814682,0.1604504658814682,-0.8099892376198776,1.8103460646896083
| 3,430
|
Membrane lipid biosynthetic process
| 15
| 22
| 3.406837
| 0.000657
|
Q06136,O15269,O43292,Q9P035,O60762,O15270,Q9NXE4,O60512,P27544,O95470,Q13510,P22059,Q96G23,P04062,Q8NBX0
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
258,286,194,294,605,295,591,18,501,86,250,316,124,30,95
|
286,295,194,18,605,86,30,316,501,2511,258,250,951,95,1083,1378,124,2761,640,591,294,1734
|
1.3894476706931538,1.3636206339195902,1.738437938975464,3.237676205824806,0.7169539114401163,2.321161071650228,3.0603364192521147,1.2984956621256847,0.8898304908049921,-0.5208177336190014,1.4661818634308703,1.5041368739934033,0.36847097049977656,2.244786155021276,0.2735187641595761,0.09468784334280253,2.066089721766653,-0.7116898323792509,0.6875712647067221,0.7461703883999292,1.3765499068522848,-0.0907134950668146
| 3,430
|
Visual loss
| 15
| 52
| 3.403378
| 0.000666
|
O14773,Q10713,P07602,P53701,P03886,O75503,O15460,Q9NZJ7,Q99519,P14854,P01889,P04439,P50897,O60313,P00403
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
162,292,38,167,73,104,398,341,340,363,369,244,22,375,28
|
906,2406,2173,1559,162,869,398,375,413,1532,104,1187,28,3330,369,73,2855,244,38,2286,2431,363,1956,2073,2458,1190,3068,1710,948,753,22,1194,524,1120,167,1198,292,2045,3296,2046,2973,2995,1128,1175,1524,1176,1134,885,340,1837,1089,341
|
0.3997325317718629,-0.4464943548499513,-0.31905629408571334,-0.02250118346835699,1.8577557582221775,0.43080383738421585,1.1117439633053623,1.1657819605638418,1.07084676596474,-0.005591913085313469,2.189571052524327,0.19301386899346543,3.0698107589013315,-1.6780491319681583,1.179204988513675,2.4178172840822203,-0.8099892376198776,1.5292904957224467,3.0127233121243298,-0.373271876429598,-0.4649705794159142,1.1925938145223307,-0.2123673195994045,-0.26542599868242417,-0.4835161673691688,0.19301386899346543,-1.0127520150653435,-0.0907134950668146,0.36847097049977656,0.5683366593475094,3.191546309151074,0.19301386899346543,0.861414936766202,0.24146991514915547,1.8459424393187207,0.19301386899346543,1.3765499068522848,-0.24767692023999524,-1.5142922206614813,-0.24767692023999524,-0.9103121062691136,-0.9306276139125141,0.24146991514915547,0.20921739577808898,0.01126068031324202,0.20921739577808898,0.24146991514915547,0.43080383738421585,1.2590315225380515,-0.1424888753229872,0.2735187641595761,1.2590315225380515
| 3,430
|
Cation transport
| 51
| 160
| 3.402967
| 0.000667
|
Q99623,P30536,P20020,P21796,P24539,Q7KZN9,P16615,Q70HW3,Q13423,P30825,O95202,Q15907,Q9H0U3,Q96NB2,Q9Y6M7,P00403,O75844,Q9HD20,Q4KMQ2,Q96ES6,P33176,P08574,Q9Y619,O75964,Q96GC9,Q15043,P42858,P55011,O43808,Q99959,Q9UDW1,Q06787,P05067,P61586,P13073,Q96PU5,Q9BXP2,Q6P4Q7,Q00325,P12235,O43772,Q8IYU8,O43865,O15173,O76024,P05023,P46934,Q9HD47,O14936,P14854,Q9NUT2
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
517,2,385,9,138,525,269,16,146,402,401,276,536,410,548,28,32,35,163,37,425,296,45,47,188,191,447,574,573,586,74,203,205,337,336,211,601,598,214,213,468,347,469,99,477,607,103,106,604,363,519
|
1772,1559,1950,2816,604,99,781,468,573,469,2832,763,1441,2031,2693,1532,32,3081,47,477,401,1639,28,1314,1220,607,205,736,1607,963,674,1221,1952,3082,2146,1567,296,2965,840,2411,3301,213,336,3047,947,363,269,1444,2109,3303,1316,2504,385,1610,1119,3191,3343,3127,9,819,138,1570,2925,774,2640,2598,2,3166,402,784,2076,425,1190,3167,1257,2149,2748,447,2835,103,1396,1075,3379,1192,1011,1573,1574,574,2080,726,2042,1259,337,1014,2555,1121,1918,214,2464,1783,1577,2187,203,988,3253,3204,1716,146,1337,1669,1670,624,191,2237,950,276,1673,163,598,1039,16,525,2161,347,1863,1130,1236,882,37,188,1499,410,211,3387,517,1552,586,1590,601,536,2370,1409,942,35,106,3429,519,1092,74,2687,2136,1530,2250,668,2964,1632,2345,1025,45,548
|
-0.12517084870498654,-0.02250118346835699,-0.2123673195994045,-0.7704316844994457,0.7169539114401163,2.211724229893288,0.522901157152449,0.9462000577616902,0.7607169539788241,0.9462000577616902,-0.7901703605422196,0.5532361269354006,0.04479749007284595,-0.24767692023999524,-0.6729168790091554,-0.005591913085313469,3.050846065270086,-1.0335027512907717,2.748363067010926,0.9321647887240839,1.0981470112960925,-0.0564914375226667,3.0698107589013315,0.1276761298241045,0.17675834803240076,0.7169539114401163,1.6777690135569574,0.5833929390939195,-0.03946755021715677,0.3527680424371989,0.6431811538013191,0.17675834803240076,-0.2123673195994045,-1.0335027512907717,-0.30111518243997987,-0.02250118346835699,1.3636206339195902,-0.9103121062691136,0.4616874064468927,-0.4464943548499513,-1.5373416114687155,1.641034754600386,1.2590315225380515,-0.992089953515064,0.36847097049977656,1.1925938145223307,1.4279535786684734,0.04479749007284595,-0.2832385860448953,-1.5373416114687155,0.1276761298241045,-0.5208177336190014,1.1388325289942267,-0.03946755021715677,0.24146991514915547,-1.2028041638743916,-1.7500104946959263,-1.096295452188383,3.489279818123242,0.47705956297724367,1.9744867066455778,-0.02250118346835699,-0.8699343008139493,0.5380910558331444,-0.6344483133432426,-0.596278947334594,3.92901774642917,-1.1599171531024435,1.0981470112960925,0.522901157152449,-0.26542599868242417,1.04340337414266,0.19301386899346543,-1.1599171531024435,0.1604504658814682,-0.30111518243997987,-0.7116898323792509,1.001966258000303,-0.7901703605422196,2.2006588969869694,0.07811250742307049,0.2735187641595761,-2.0237575733036444,0.19301386899346543,0.32121625895525563,-0.02250118346835699,-0.02250118346835699,0.7607169539788241,-0.26542599868242417,0.5984052493734849,-0.24767692023999524,0.1604504658814682,1.2590315225380515,0.32121625895525563,-0.558403728184664,0.24146991514915547,-0.1948058268211105,1.641034754600386,-0.4835161673691688,-0.12517084870498654,-0.02250118346835699,-0.31905629408571334,1.7021191193583658,0.33701658189477507,-1.3560056220962575,-1.2243922216969028,-0.0907134950668146,1.9280968875332776,0.11120892157867891,-0.07357327446040215,-0.07357327446040215,0.7022834886797121,1.750489731196436,-0.33706243340680064,0.36847097049977656,1.4151493408700357,-0.07357327446040215,1.8577557582221775,0.7315827923762055,0.30536674022651894,3.2651743542921823,0.861414936766202,-0.30111518243997987,1.2458108826688405,-0.15986707294579158,0.24146991514915547,0.17675834803240076,0.43080383738421585,3.0222783212407616,1.7625145060761207,0.02805701137235168,1.0845146796370766,1.6655522802639968,-2.1012974711813244,0.8756421363992508,-0.005591913085313469,0.7461703883999292,-0.02250118346835699,0.7315827923762055,0.8328430643605732,-0.40974773902190176,0.07811250742307049,0.3841256925736641,3.0318170762153325,2.189571052524327,-11.531405437931214,0.8756421363992508,0.2735187641595761,2.4178172840822203,-0.6536448751928122,-0.2832385860448953,0.01126068031324202,-0.33706243340680064,0.65802036299361,-0.8900812583352817,-0.03946755021715677,-0.3914762369552328,0.32121625895525563,2.7982738550861823,0.8184979173823138
| 3,430
|
Abnormal heart valve morphology
| 26
| 82
| 3.390602
| 0.000697
|
P61978,P51798,P06280,O95202,Q6DKJ4,P21964,P08236,P04062,O75844,Q12768,P37268,P53701,P16278,Q9Y4P3,P55795,Q06787,O15360,Q9UL01,Q96L58,Q96PU5,O96028,Q6PGP7,Q6ZXV5,P01889,Q9UHX1,Q14738
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
387,524,275,401,406,280,279,30,32,550,166,167,43,313,196,203,454,79,339,211,334,480,233,369,118,254
|
1472,1160,1438,2767,454,3060,2350,837,1161,1473,1010,32,1777,401,334,369,1534,858,30,275,2819,279,2431,1189,43,3127,2073,280,3163,2800,3066,2775,2413,2149,166,2078,2668,2749,524,619,167,2670,821,196,2083,387,2043,1331,2879,1198,2934,1296,2556,203,550,2626,1202,254,2299,1078,2439,406,580,480,233,2729,2422,339,211,2312,1242,3371,2022,2102,1092,750,2737,118,866,79,2066,313
|
0.02805701137235168,0.20921739577808898,0.04479749007284595,-0.7311921139115007,0.9741576934609325,-1.0127520150653435,-0.40974773902190176,0.4616874064468927,0.20921739577808898,0.02805701137235168,0.32121625895525563,3.050846065270086,-0.12517084870498654,1.0981470112960925,1.2590315225380515,1.179204988513675,-0.005591913085313469,0.44626893355334946,3.0603364192521147,1.4151493408700357,-0.7704316844994457,1.402314093228658,-0.4649705794159142,0.19301386899346543,2.9065277890482055,-1.096295452188383,-0.26542599868242417,1.402314093228658,-1.1599171531024435,-0.7507725016906376,-1.0127520150653435,-0.7311921139115007,-0.4464943548499513,-0.30111518243997987,1.8459424393187207,-0.26542599868242417,-0.6536448751928122,-0.7116898323792509,0.861414936766202,0.7022834886797121,1.8459424393187207,-0.6536448751928122,0.47705956297724367,1.738437938975464,-0.26542599868242417,1.1388325289942267,-0.24767692023999524,0.11120892157867891,-0.8298890333091614,0.19301386899346543,-0.8699343008139493,0.14408985151272588,-0.558403728184664,1.7021191193583658,0.8041129767098191,-0.6153265492951593,0.19301386899346543,1.4915153034770001,-0.373271876429598,0.2735187641595761,-0.4649705794159142,1.0845146796370766,0.7607169539788241,0.9321647887240839,1.5792439505261,-0.6922649775615227,-0.4464943548499513,1.2590315225380515,1.6655522802639968,-0.373271876429598,0.17675834803240076,-1.9474917631058593,-0.22999085661134913,-0.26542599868242417,0.2735187641595761,0.5833929390939195,-0.6922649775615227,2.1113172784145564,0.44626893355334946,2.3750691920218543,-0.24767692023999524,1.3246420617522143
| 3,430
|
Azurophil granule
| 26
| 70
| 3.378595
| 0.000729
|
P61916,O00560,P06865,P06280,Q9H0U3,P08236,P07602,Q13277,P16278,Q92820,Q9Y5Z4,P10253,P07437,P17900,Q9BTY2,Q9NZJ7,P15586,P42785,Q9H7Z7,O00584,Q9NQX7,P10619,O15260,P13473,Q8NF37,Q07065
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
512,266,268,275,536,279,38,427,43,433,50,311,310,66,202,341,206,207,474,467,225,226,98,237,506,253
|
266,467,977,98,1071,553,1355,2455,870,1876,895,275,268,1952,310,38,1358,279,311,226,1955,646,237,983,206,43,66,2800,3344,2228,207,2928,3270,912,2461,1011,1855,3105,2387,2463,512,787,1644,2648,3107,2511,253,1335,427,2298,812,2055,506,612,433,3075,1155,3109,1938,2887,1304,202,536,474,225,3021,341,1734,2740,50
|
1.4407269703301229,0.9462000577616902,0.33701658189477507,2.2227671511588163,0.2735187641595761,0.7896879996375533,0.09468784334280253,-0.4835161673691688,0.43080383738421585,-0.1773059016141884,0.41529180787632924,1.4151493408700357,1.4279535786684734,-0.2123673195994045,1.3246420617522143,3.0127233121243298,0.09468784334280253,1.402314093228658,1.3246420617522143,1.6040461907838122,-0.2123673195994045,0.6728169776242082,1.554325783520826,0.33701658189477507,1.6777690135569574,2.9065277890482055,2.4918352621956807,-0.7507725016906376,-1.7500104946959263,-0.33706243340680064,1.6777690135569574,-0.8699343008139493,-1.4231985981949864,0.3997325317718629,-0.4835161673691688,0.32121625895525563,-0.15986707294579158,-1.0543430004362901,-0.4280869276823581,-0.4835161673691688,0.8756421363992508,0.522901157152449,-0.0564914375226667,-0.6344483133432426,-1.0543430004362901,-0.5208177336190014,1.4915153034770001,0.11120892157867891,1.04340337414266,-0.373271876429598,0.4923857069491886,-0.24767692023999524,0.8898304908049921,0.7169539114401163,1.0296274822176772,-1.0127520150653435,0.22536929144369766,-1.0543430004362901,-0.1948058268211105,-0.8298890333091614,0.14408985151272588,1.7142527679704935,0.8328430643605732,0.9462000577616902,1.6164042064007391,-0.9510285615071858,1.2590315225380515,-0.0907134950668146,-0.6922649775615227,2.68787200548125
| 3,430
|
Primary active transmembrane transporter activity
| 26
| 56
| 3.377354
| 0.000732
|
P20020,P51970,O14678,P51798,Q7KZN9,P16615,O95168,O43676,P00403,Q9P0J0,O75306,P08183,Q9HD20,P08574,P06576,P28288,Q9Y6M9,P03886,Q9UDW1,P13073,Q03519,Q03518,P05023,O96000,P14854,Q9NUT2
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
385,386,257,524,525,269,529,21,28,158,413,159,35,296,674,555,326,73,74,336,215,218,607,606,363,519
|
892,1950,257,926,21,2922,763,1441,413,978,671,1442,529,3008,2033,606,28,73,607,674,159,296,840,336,363,269,2639,385,1119,3191,3343,819,555,3031,784,2149,2748,1075,3152,524,386,1259,218,215,900,3131,1673,525,35,2445,519,158,74,2136,2067,326
|
0.41529180787632924,-0.2123673195994045,1.4661818634308703,0.3841256925736641,3.200802504118346,-0.8699343008139493,0.5532361269354006,0.04479749007284595,1.07084676596474,0.33701658189477507,0.6431811538013191,0.04479749007284595,0.8471486580863727,-0.9510285615071858,-0.24767692023999524,0.7169539114401163,3.0698107589013315,2.4178172840822203,0.7169539114401163,0.6431811538013191,1.8695432160167267,1.3636206339195902,0.4616874064468927,1.2590315225380515,1.1925938145223307,1.4279535786684734,-0.6344483133432426,1.1388325289942267,0.24146991514915547,-1.2028041638743916,-1.7500104946959263,0.47705956297724367,0.7896879996375533,-0.971515740451046,0.522901157152449,-0.30111518243997987,-0.7116898323792509,0.2735187641595761,-1.1386163266404463,0.861414936766202,1.1388325289942267,0.1604504658814682,1.6287336796515217,1.641034754600386,0.41529180787632924,-1.096295452188383,-0.07357327446040215,0.861414936766202,3.0318170762153325,-0.4649705794159142,0.8756421363992508,1.8813049364421908,2.4178172840822203,-0.2832385860448953,-0.24767692023999524,1.2853737321434007
| 3,430
|
Abnormality of head blood vessel
| 11
| 25
| 3.360892
| 0.000777
|
P17900,P10619,P07602,P03886,P16278,Q9NZJ7,Q99519,P06865,Q9Y4P3,Q13510,P21964
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
66,226,38,73,43,341,340,268,313,250,280
|
1472,1438,1439,2350,73,268,38,1358,226,2878,43,66,2073,280,2775,360,2670,2879,250,2299,2422,340,341,866,313
|
0.02805701137235168,0.04479749007284595,0.04479749007284595,-0.40974773902190176,2.4178172840822203,1.4279535786684734,3.0127233121243298,0.09468784334280253,1.6040461907838122,-0.8298890333091614,2.9065277890482055,2.4918352621956807,-0.26542599868242417,1.402314093228658,-0.7311921139115007,1.2059486289837344,-0.6536448751928122,-0.8298890333091614,1.5041368739934033,-0.373271876429598,-0.4464943548499513,1.2590315225380515,1.2590315225380515,0.44626893355334946,1.3246420617522143
| 3,430
|
Abnormality of the optic nerve
| 74
| 262
| 3.359834
| 0.00078
|
Q7LGA3,P61978,P38435,O95630,P78318,P51798,Q7KZN9,Q9H061,Q92974,Q96CU9,O15460,P06280,O43676,P50897,Q15907,O95202,P98175,P21964,P00403,P04062,Q9P0J0,P49902,Q9H9P8,O95831,Q96KP1,Q10713,Q12768,P07602,P37268,Q86Y39,O75306,P16278,Q13277,P49770,O43681,Q9NZ08,Q9NVI7,Q9Y287,Q15043,Q15067,P04350,O43292,Q9Y6M9,P55011,Q9NPL8,P42858,O75648,P03886,P61586,Q9NZJ7,Q99519,Q96L58,Q96PU5,O96028,Q6P4Q7,Q9UG56,Q9Y2Z2,Q00839,O76024,O96000,O60762,O14936,Q6ZXV5,Q9UBM7,Q8TCJ2,P01889,Q8NAT1,Q5XKP0,P04439,Q9UHX1,Q96PZ0,P51812,Q9H490,O60313
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
128,387,136,522,649,524,525,12,526,274,398,275,21,22,276,401,281,280,28,30,158,160,688,414,686,292,550,38,166,168,413,43,427,557,553,185,443,190,191,319,445,194,326,574,325,447,444,73,337,341,340,339,211,334,598,487,488,609,477,606,605,604,233,632,628,369,115,626,244,118,498,619,640,375
|
906,1472,892,3401,1948,1559,1950,977,2816,1438,604,869,398,1328,194,1439,752,21,2922,553,1142,961,375,2832,605,1473,1776,3300,1441,413,2410,978,1056,1532,1442,1638,444,2818,3149,477,1533,2947,1777,2179,401,2033,1810,1565,522,414,606,2595,334,28,369,73,30,445,244,1877,275,1254,38,2286,1953,3189,2035,1189,2878,983,43,896,1956,1880,2639,1415,3191,280,1665,1997,1850,1851,3031,3011,795,1747,1812,1190,1074,3068,2413,1572,166,136,2748,739,447,1541,2507,1075,796,1543,2967,557,3152,160,2991,2079,22,694,524,619,1120,2670,574,1290,3129,1544,3360,2292,337,387,3034,2992,649,1333,281,1783,609,1199,2934,808,3295,292,2045,550,3296,1921,2558,427,2626,1646,2750,1322,1488,191,319,1126,1374,2996,276,1673,968,680,2092,2841,626,2051,744,2726,598,1104,1235,233,2442,525,1171,128,1897,2563,1795,2846,3017,3073,168,1128,1681,1493,1494,2010,1206,1426,2276,115,2680,998,935,628,1497,2057,2240,1131,1524,2422,526,1176,1624,274,1044,1209,2202,2732,3055,686,339,211,498,937,792,2312,1303,885,340,1837,3001,2124,2016,1463,2518,1212,904,3172,3231,12,1136,1730,2685,640,688,850,1944,325,2208,1764,2022,443,1984,2101,185,341,749,158,1092,632,487,3397,118,2543,2875,855,761,1216,190,2572,488,3213,2213,1808,3043,1025,1698,326
|
0.3997325317718629,0.02805701137235168,0.41529180787632924,-2.397311077076706,-0.2123673195994045,-0.02250118346835699,-0.2123673195994045,0.33701658189477507,-0.7704316844994457,0.04479749007284595,0.7169539114401163,0.43080383738421585,1.1117439633053623,0.11120892157867891,1.738437938975464,0.04479749007284595,0.5683366593475094,3.200802504118346,-0.8699343008139493,0.7896879996375533,0.22536929144369766,0.3527680424371989,1.1657819605638418,-0.7901703605422196,0.7169539114401163,0.02805701137235168,-0.12517084870498654,-1.5373416114687155,0.04479749007284595,1.07084676596474,-0.4464943548499513,0.33701658189477507,0.2894676887918951,-0.005591913085313469,0.04479749007284595,-0.0564914375226667,1.001966258000303,-0.7704316844994457,-1.1386163266404463,0.9321647887240839,-0.005591913085313469,-0.8900812583352817,-0.12517084870498654,-0.31905629408571334,1.0981470112960925,-0.24767692023999524,-0.1424888753229872,-0.02250118346835699,0.861414936766202,1.07084676596474,0.7169539114401163,-0.596278947334594,1.2590315225380515,3.0698107589013315,1.179204988513675,2.4178172840822203,3.0603364192521147,1.001966258000303,1.5292904957224467,-0.1773059016141884,1.4151493408700357,0.1604504658814682,3.0127233121243298,-0.373271876429598,-0.2123673195994045,-1.2028041638743916,-0.24767692023999524,0.19301386899346543,-0.8298890333091614,0.33701658189477507,2.9065277890482055,0.41529180787632924,-0.2123673195994045,-0.1773059016141884,-0.6344483133432426,0.06148252180205109,-1.2028041638743916,1.402314093228658,-0.07357327446040215,-0.22999085661134913,-0.15986707294579158,-0.15986707294579158,-0.971515740451046,-0.9510285615071858,0.5076661391022604,-0.10791253841717666,-0.1424888753229872,0.19301386899346543,0.2735187641595761,-1.0127520150653435,-0.4464943548499513,-0.02250118346835699,1.8459424393187207,1.9975331678372859,-0.7116898323792509,0.5833929390939195,1.001966258000303,-0.005591913085313469,-0.5208177336190014,0.2735187641595761,0.5076661391022604,-0.005591913085313469,-0.9103121062691136,0.7896879996375533,-1.1386163266404463,1.8695432160167267,-0.9306276139125141,-0.26542599868242417,3.191546309151074,0.6282990804246098,0.861414936766202,0.7022834886797121,0.24146991514915547,-0.6536448751928122,0.7607169539788241,0.14408985151272588,-1.096295452188383,-0.005591913085313469,-1.8477085071425041,-0.373271876429598,1.2590315225380515,1.1388325289942267,-0.971515740451046,-0.9306276139125141,0.6728169776242082,0.11120892157867891,1.402314093228658,-0.12517084870498654,0.7169539114401163,0.19301386899346543,-0.8699343008139493,0.4923857069491886,-1.5142922206614813,1.3765499068522848,-0.24767692023999524,0.8041129767098191,-1.5142922206614813,-0.1948058268211105,-0.558403728184664,1.04340337414266,-0.6153265492951593,-0.0564914375226667,-0.7116898323792509,0.1276761298241045,0.02805701137235168,1.750489731196436,1.2984956621256847,0.24146991514915547,0.09468784334280253,-0.9306276139125141,1.4151493408700357,-0.07357327446040215,0.3527680424371989,0.6431811538013191,-0.26542599868242417,-0.7901703605422196,0.7022834886797121,-0.24767692023999524,0.5833929390939195,-0.6922649775615227,0.7315827923762055,0.25751962221115077,0.17675834803240076,1.5792439505261,-0.4649705794159142,0.861414936766202,0.20921739577808898,2.0547236877093185,-0.1773059016141884,-0.558403728184664,-0.12517084870498654,-0.7901703605422196,-0.9510285615071858,-1.0127520150653435,1.8459424393187207,0.24146991514915547,-0.07357327446040215,0.02805701137235168,0.02805701137235168,-0.22999085661134913,0.19301386899346543,0.06148252180205109,-0.35513411913799386,2.156171440265243,-0.6536448751928122,0.33701658189477507,0.3841256925736641,0.7022834886797121,0.02805701137235168,-0.24767692023999524,-0.33706243340680064,0.24146991514915547,0.01126068031324202,-0.4464943548499513,0.861414936766202,0.20921739577808898,-0.03946755021715677,1.4279535786684734,0.30536674022651894,0.19301386899346543,-0.31905629408571334,-0.6922649775615227,-0.992089953515064,0.6431811538013191,1.2590315225380515,1.6655522802639968,0.903980231650309,0.3841256925736641,0.522901157152449,-0.373271876429598,0.14408985151272588,0.43080383738421585,1.2590315225380515,-0.1424888753229872,-0.9306276139125141,-0.2832385860448953,-0.22999085661134913,0.04479749007284595,-0.5208177336190014,0.19301386899346543,0.41529180787632924,-1.1599171531024435,-1.289746149293953,3.4362955117330025,0.24146991514915547,-0.0907134950668146,-0.6536448751928122,0.6875712647067221,0.6431811538013191,0.4616874064468927,-0.1948058268211105,1.2853737321434007,-0.31905629408571334,-0.10791253841717666,-0.22999085661134913,1.0158151806848401,-0.2123673195994045,-0.26542599868242417,1.774512395985724,1.2590315225380515,0.5833929390939195,1.8813049364421908,0.2735187641595761,0.7022834886797121,0.9321647887240839,-2.2874512966961964,2.1113172784145564,-0.5395748804972572,-0.8099892376198776,0.4616874064468927,0.5683366593475094,0.19301386899346543,1.7625145060761207,-0.558403728184664,0.9321647887240839,-1.2460779206914567,-0.31905629408571334,-0.12517084870498654,-0.971515740451046,0.32121625895525563,-0.07357327446040215,1.2853737321434007
| 3,430
|
Corneal opacity
| 21
| 59
| 3.358862
| 0.000783
|
Q06136,P06280,O95202,P08236,P04062,O75844,O43683,P53701,P16278,Q9Y4P3,Q9NVI7,Q6NUK1,Q99519,O75845,O96028,O75569,Q16625,P10619,P51648,Q8NAT1,Q13510
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
258,275,401,279,30,32,539,167,43,313,443,580,340,470,334,342,346,226,110,115,250
|
977,1438,869,1738,752,539,2987,2350,1097,2574,1056,342,32,470,2179,401,334,1534,30,895,275,279,2431,226,43,896,1415,928,2775,739,1543,2079,110,1120,167,821,2879,1450,2703,258,2046,2626,250,2299,2366,2996,346,580,1796,115,2729,340,850,443,1596,632,866,2875,313
|
0.33701658189477507,0.04479749007284595,0.43080383738421585,-0.10791253841717666,0.5683366593475094,0.8184979173823138,-0.9306276139125141,-0.40974773902190176,0.25751962221115077,-0.5773048800496771,0.2894676887918951,1.2458108826688405,3.050846065270086,0.9462000577616902,-0.31905629408571334,1.0981470112960925,1.2590315225380515,-0.005591913085313469,3.0603364192521147,0.41529180787632924,1.4151493408700357,1.402314093228658,-0.4649705794159142,1.6040461907838122,2.9065277890482055,0.41529180787632924,0.06148252180205109,0.3841256925736641,-0.7311921139115007,0.5833929390939195,-0.005591913085313469,-0.26542599868242417,2.1784605959005607,0.24146991514915547,1.8459424393187207,0.47705956297724367,-0.8298890333091614,0.04479749007284595,-0.6729168790091554,1.4661818634308703,-0.24767692023999524,-0.6153265492951593,1.5041368739934033,-0.373271876429598,-0.40974773902190176,-0.9306276139125141,1.2458108826688405,0.7607169539788241,-0.12517084870498654,2.156171440265243,-0.6922649775615227,1.2590315225380515,0.4616874064468927,1.0158151806848401,-0.02250118346835699,0.7022834886797121,0.44626893355334946,-0.8099892376198776,1.3246420617522143
| 3,430
|
Intrinsic component of mitochondrial inner membrane
| 18
| 30
| 3.353366
| 0.000798
|
Q9UG56,Q9H9P8,Q9BUR5,Q00325,Q13505,Q16891,Q6P4A7,O14925,Q99595,Q9Y2R0,O60830,Q9Y512,Q16134,Q15070,Q5XKP0,Q96NB2,Q6UXV4,Q9NVH1
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
487,688,613,214,58,479,232,204,78,19,20,278,533,181,626,410,697,616
|
204,1142,20,1010,1029,839,3050,1163,214,58,181,533,479,951,626,232,697,1130,410,78,613,3002,942,688,616,732,487,19,1025,278
|
1.6777690135569574,0.22536929144369766,3.2100435371001237,0.32121625895525563,0.30536674022651894,0.4616874064468927,-0.992089953515064,0.20921739577808898,1.641034754600386,2.5544966637542177,1.7864835322979642,0.8328430643605732,0.9321647887240839,0.36847097049977656,0.7022834886797121,1.5792439505261,0.6282990804246098,0.24146991514915547,1.0845146796370766,2.3750691920218543,0.7169539114401163,-0.9306276139125141,0.3841256925736641,0.6431811538013191,0.7169539114401163,0.5984052493734849,0.9321647887240839,3.2192694624153164,0.32121625895525563,1.4151493408700357
| 3,430
|
Ceramide metabolic process
| 11
| 18
| 3.351322
| 0.000804
|
P17900,O15269,O15270,P06865,O60512,P06280,O95470,Q13510,Q8NCC3,Q96G23,P04062
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
66,286,295,268,18,275,86,250,91,124,30
|
286,295,18,86,30,275,268,1358,66,501,795,2511,250,951,91,124,340,591
|
1.3894476706931538,1.3636206339195902,3.237676205824806,2.321161071650228,3.0603364192521147,1.4151493408700357,1.4279535786684734,0.09468784334280253,2.4918352621956807,0.8898304908049921,0.5076661391022604,-0.5208177336190014,1.5041368739934033,0.36847097049977656,2.277649032464161,2.066089721766653,1.2590315225380515,0.7461703883999292
| 3,430
|
Lytic vacuole organization
| 10
| 24
| 3.347982
| 0.000814
|
P42345,O14773,O75503,P50897,P04062,P10253,Q8N511,P54802,Q14108,Q14457
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
353,162,104,22,30,311,25,87,60,287
|
2026,162,104,2285,30,1358,311,370,353,22,1364,87,2186,550,60,287,812,25,1624,2759,3158,1504,1050,2475
|
-0.24767692023999524,1.8577557582221775,2.189571052524327,-0.373271876429598,3.0603364192521147,0.09468784334280253,1.3246420617522143,1.179204988513675,1.2192696206606266,3.191546309151074,0.09468784334280253,2.321161071650228,-0.31905629408571334,0.8041129767098191,2.5336885717746562,1.3894476706931538,0.4923857069491886,3.1263237819839285,-0.03946755021715677,-0.7116898323792509,-1.1386163266404463,0.02805701137235168,0.30536674022651894,-0.4835161673691688
| 3,430
|
Abnormal cellular phenotype
| 45
| 199
| 3.305128
| 0.000949
|
P51970,P11177,P51798,Q9UBX3,Q7KZN9,Q96CU9,Q70HW3,Q13315,Q9Y2R0,O43676,Q16134,P21964,P00403,Q9P0J0,P04062,O75844,P23786,O14773,O75306,P07602,Q86Y39,Q9UJW0,P09601,Q14108,Q9Y6M9,Q9NPL8,O75648,P03886,Q06787,O15360,P15586,Q9NZJ7,P13073,Q00325,P12235,O43772,Q14739,P42345,Q6PGP7,Q15904,O75503,P35637,Q4J6C6,Q9Y584,Q13510
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
386,509,524,13,525,274,16,400,19,21,533,280,28,158,30,32,33,162,413,38,168,180,59,60,326,325,444,73,203,454,206,341,336,214,213,468,222,353,480,490,104,235,371,119,250
|
1472,2026,892,1948,1559,1389,1950,977,162,3148,454,21,2922,468,837,1097,2409,1441,413,978,1442,104,444,32,1029,2033,2743,1414,606,28,3027,1534,1314,73,30,1877,38,2035,59,1568,2924,676,3009,509,3358,3046,213,3340,2549,336,3028,1223,206,1743,1444,1146,896,1956,2639,1415,1119,2353,3127,693,280,1997,33,2459,1851,2772,2287,3031,3049,2227,3011,1747,2263,3167,235,2926,3168,2078,2111,948,353,1395,2507,775,2699,796,1258,3152,2361,2079,1363,2509,524,386,2669,2483,2670,2326,2623,2387,2044,695,214,1450,1817,3194,2511,203,1968,3296,1857,2418,400,3071,250,1228,1646,60,222,2995,3220,2439,2366,490,533,1673,625,968,1893,371,651,2092,2786,2907,480,16,525,2302,2846,168,996,1493,1206,935,2565,3261,1083,1683,2422,1176,1378,1459,1624,2873,274,1156,1044,2308,685,1864,1865,937,885,1837,1325,2518,1242,1408,536,816,1089,3371,325,1803,1502,2022,341,749,158,3124,13,708,180,2712,1247,1696,19,2616,3213,2405,1025,119,2815,2281,326
|
0.02805701137235168,-0.24767692023999524,0.41529180787632924,-0.2123673195994045,-0.02250118346835699,0.07811250742307049,-0.2123673195994045,0.33701658189477507,1.8577557582221775,-1.1386163266404463,0.9741576934609325,3.200802504118346,-0.8699343008139493,0.9462000577616902,0.4616874064468927,0.25751962221115077,-0.4464943548499513,0.04479749007284595,1.07084676596474,0.33701658189477507,0.04479749007284595,2.189571052524327,1.001966258000303,3.050846065270086,0.30536674022651894,-0.24767692023999524,-0.7116898323792509,0.06148252180205109,0.7169539114401163,3.0698107589013315,-0.971515740451046,-0.005591913085313469,0.1276761298241045,2.4178172840822203,3.0603364192521147,-0.1773059016141884,3.0127233121243298,-0.24767692023999524,2.54410242985927,-0.02250118346835699,-0.8699343008139493,0.6431811538013191,-0.9510285615071858,0.8756421363992508,-1.8477085071425041,-0.992089953515064,1.641034754600386,-1.725900749051077,-0.558403728184664,1.2590315225380515,-0.971515740451046,0.17675834803240076,1.6777690135569574,-0.10791253841717666,0.04479749007284595,0.22536929144369766,0.41529180787632924,-0.2123673195994045,-0.6344483133432426,0.06148252180205109,0.24146991514915547,-0.40974773902190176,-1.096295452188383,0.6282990804246098,1.402314093228658,-0.22999085661134913,3.0318170762153325,-0.4835161673691688,-0.15986707294579158,-0.7311921139115007,-0.373271876429598,-0.971515740451046,-0.992089953515064,-0.33706243340680064,-0.9510285615071858,-0.10791253841717666,-0.35513411913799386,-1.1599171531024435,1.5667994320520733,-0.8699343008139493,-1.1599171531024435,-0.26542599868242417,-0.2832385860448953,0.36847097049977656,1.2192696206606266,0.07811250742307049,-0.5208177336190014,0.5380910558331444,-0.6729168790091554,0.5076661391022604,0.1604504658814682,-1.1386163266404463,-0.40974773902190176,-0.26542599868242417,0.09468784334280253,-0.5208177336190014,0.861414936766202,1.1388325289942267,-0.6536448751928122,-0.5021316919187672,-0.6536448751928122,-0.3914762369552328,-0.6153265492951593,-0.4280869276823581,-0.24767692023999524,0.6282990804246098,1.641034754600386,0.04479749007284595,-0.1424888753229872,-1.2028041638743916,-0.5208177336190014,1.7021191193583658,-0.2123673195994045,-1.5142922206614813,-0.15986707294579158,-0.4464943548499513,1.1117439633053623,-1.0127520150653435,1.5041368739934033,0.17675834803240076,-0.0564914375226667,2.5336885717746562,1.6164042064007391,-0.9306276139125141,-1.267862233870033,-0.4649705794159142,-0.40974773902190176,0.9180915884762,0.8328430643605732,-0.07357327446040215,0.7022834886797121,0.3527680424371989,-0.1773059016141884,1.179204988513675,0.6728169776242082,-0.26542599868242417,-0.7311921139115007,-0.8498704751461239,0.9321647887240839,3.2651743542921823,0.861414936766202,-0.373271876429598,-0.7901703605422196,1.8459424393187207,0.33701658189477507,0.02805701137235168,0.19301386899346543,0.3841256925736641,-0.558403728184664,-1.3782981393570042,0.2735187641595761,-0.07357327446040215,-0.4464943548499513,0.20921739577808898,0.09468784334280253,0.04479749007284595,-0.03946755021715677,-0.8099892376198776,1.4279535786684734,0.22536929144369766,0.30536674022651894,-0.373271876429598,0.6431811538013191,-0.15986707294579158,-0.15986707294579158,0.3841256925736641,0.43080383738421585,-0.1424888753229872,0.1276761298241045,-0.5208177336190014,0.17675834803240076,0.07811250742307049,0.8328430643605732,0.4923857069491886,0.2735187641595761,-1.9474917631058593,1.2853737321434007,-0.12517084870498654,0.02805701137235168,-0.22999085661134913,1.2590315225380515,0.5833929390939195,1.8813049364421908,-1.075273613042021,3.391761695054266,0.6282990804246098,1.798428045397234,-0.6729168790091554,0.17675834803240076,-0.07357327446040215,3.2192694624153164,-0.596278947334594,-1.2460779206914567,-0.4280869276823581,0.32121625895525563,2.1113172784145564,-0.7507725016906376,-0.35513411913799386,1.2853737321434007
| 3,430
|
Glycosylation
| 20
| 47
| 3.280817
| 0.001035
|
O60512,O60502,Q9H0U3,P04062,Q2TAA5,Q16706,Q8N4A0,P46977,Q86YN1,Q10472,Q96L58,O60476,O60762,Q6ZXV5,O75503,Q9BT22,P04844,O15118,Q8NAT1,O60568
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
18,147,536,30,288,551,172,430,453,456,339,227,605,233,104,494,362,109,115,376
|
2107,109,2767,752,837,227,147,18,376,605,1356,104,2743,30,872,362,2228,430,2836,2484,1296,2608,914,875,456,1646,1484,551,288,233,1723,453,172,115,628,339,1657,494,536,1138,3424,850,2963,1556,2687,1349,1698
|
-0.2832385860448953,2.1784605959005607,-0.7311921139115007,0.5683366593475094,0.4616874064468927,1.5916594876052144,1.904751655596212,3.237676205824806,1.1657819605638418,0.7169539114401163,0.09468784334280253,2.189571052524327,-0.7116898323792509,3.0603364192521147,0.43080383738421585,1.1925938145223307,-0.33706243340680064,1.0296274822176772,-0.7901703605422196,-0.5021316919187672,0.14408985151272588,-0.596278947334594,0.3997325317718629,0.43080383738421585,0.9741576934609325,-0.0564914375226667,0.02805701137235168,0.8041129767098191,1.3894476706931538,1.5792439505261,-0.0907134950668146,0.98808050071691,1.8341031346457968,2.156171440265243,0.7022834886797121,1.2590315225380515,-0.0564914375226667,0.9180915884762,0.8328430643605732,0.24146991514915547,-4.1411192303358,0.4616874064468927,-0.8900812583352817,-0.005591913085313469,-0.6536448751928122,0.11120892157867891,-0.07357327446040215
| 3,430
|
Amide binding
| 31
| 110
| 3.273769
| 0.001061
|
P24390,Q9UIQ6,P21796,P10321,P45880,O00264,Q15392,O14773,P07602,Q8WTV0,Q9UM22,Q9Y680,Q9NZ08,Q9Y287,P42892,O60684,P00374,Q9NZJ7,Q92973,Q03519,Q03518,Q9BYT8,O43731,Q9NQX7,Q96AY3,P55899,P01889,P04439,P52294,Q9Y584,P35610
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
6,137,9,393,15,143,23,162,38,169,51,56,185,190,69,198,76,341,208,215,218,349,97,225,357,111,369,244,117,119,252
|
2986,1848,143,1248,1908,1116,3427,2796,162,2348,1635,926,2921,97,198,2381,1098,76,369,244,1811,3421,38,1285,3126,3233,393,3415,2148,2353,9,2261,3328,6,1611,3064,2640,2598,1317,965,252,657,2642,739,948,69,2952,15,3282,796,1258,1915,862,2079,3400,966,117,1033,575,111,2862,1014,2702,2804,2904,1645,1577,218,215,3194,1578,2839,1922,2722,2704,1372,3183,900,23,407,970,169,2338,208,357,1460,1270,3404,2166,517,1085,2912,349,849,1659,474,816,225,1277,185,341,1053,2571,137,51,3079,190,3043,119,56
|
-0.9306276139125141,-0.15986707294579158,1.9513415899455118,0.1604504658814682,-0.1948058268211105,0.24146991514915547,-4.650483787176411,-0.7507725016906376,1.8577557582221775,-0.40974773902190176,-0.0564914375226667,0.3841256925736641,-0.8699343008139493,2.233787760016152,1.7263589960332117,-0.4280869276823581,0.25751962221115077,2.3964848636249685,1.179204988513675,1.5292904957224467,-0.1424888753229872,-3.7873509360750597,3.0127233121243298,0.14408985151272588,-1.096295452188383,-1.3117306703903504,1.125305736257329,-3.285316956235847,-0.30111518243997987,-0.40974773902190176,3.489279818123242,-0.35513411913799386,-1.6543045466896755,3.713359366894026,-0.03946755021715677,-1.0127520150653435,-0.6344483133432426,-0.596278947334594,0.1276761298241045,0.3527680424371989,1.4915153034770001,0.65802036299361,-0.6344483133432426,0.5833929390939195,0.36847097049977656,2.4496613605694386,-0.8900812583352817,3.2925394092933984,-1.468526945815869,0.5076661391022604,0.1604504658814682,-0.1948058268211105,0.44626893355334946,-0.26542599868242417,-2.3420518460725406,0.3527680424371989,2.1113172784145564,0.30536674022651894,0.7607169539788241,2.1784605959005607,-0.8099892376198776,0.32121625895525563,-0.6729168790091554,-0.7507725016906376,-0.8498704751461239,-0.0564914375226667,-0.02250118346835699,1.6287336796515217,1.641034754600386,-1.2028041638743916,-0.02250118346835699,-0.7901703605422196,-0.1948058268211105,-0.6922649775615227,-0.6729168790091554,0.09468784334280253,-1.1813127889529935,0.41529180787632924,3.1543688124281597,1.0845146796370766,0.3527680424371989,1.8459424393187207,-0.3914762369552328,1.6777690135569574,1.2192696206606266,0.04479749007284595,0.1604504658814682,-2.4814738005103227,-0.30111518243997987,0.8756421363992508,0.2735187641595761,-0.8498704751461239,1.2458108826688405,0.4616874064468927,-0.0564914375226667,0.9462000577616902,0.4923857069491886,1.6164042064007391,0.1604504658814682,1.774512395985724,1.2590315225380515,0.30536674022651894,-0.558403728184664,1.9975331678372859,2.677725710562994,-1.0127520150653435,1.7625145060761207,-0.971515740451046,2.1113172784145564,2.606176282501621
| 3,430
|
Glycosaminoglycan metabolism
| 9
| 15
| 3.273232
| 0.001063
|
Q7LGA3,P16278,P15586,Q9UL01,P06865,O60512,P54802,Q8TB61,P08236
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
128,43,206,79,268,18,87,55,279
|
1664,752,18,1637,268,1358,279,206,43,87,128,55,339,2687,79
|
-0.07357327446040215,0.5683366593475094,3.237676205824806,-0.0564914375226667,1.4279535786684734,0.09468784334280253,1.402314093228658,1.6777690135569574,2.9065277890482055,2.321161071650228,2.0547236877093185,2.606176282501621,1.2590315225380515,-0.6536448751928122,2.3750691920218543
| 3,430
|
Glycoside hydrolase superfamily [IPR017853]
| 8
| 16
| 3.26976
| 0.001076
|
Q9BTY2,P16278,P06865,P06280,O60502,P54802,P08236,P04062
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
202,43,268,275,147,87,279,30
|
147,30,895,275,268,1358,1567,279,311,43,1224,87,741,1202,202,1066
|
1.904751655596212,3.0603364192521147,0.41529180787632924,1.4151493408700357,1.4279535786684734,0.09468784334280253,-0.02250118346835699,1.402314093228658,1.3246420617522143,2.9065277890482055,0.17675834803240076,2.321161071650228,0.5833929390939195,0.19301386899346543,1.7142527679704935,0.2894676887918951
| 3,430
|
Carbohydrate derivative catabolic process
| 16
| 38
| 3.267554
| 0.001085
|
P49902,P17900,Q9BTY2,P16278,P15586,Q99519,P06865,Q9H773,P06280,Q13126,O60502,P35610,P54802,P08236,Q9NUJ1,P04062
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
160,66,202,43,206,340,268,305,275,113,147,252,87,279,221,30
|
350,2986,147,3027,2618,30,895,275,268,1358,279,2549,206,43,66,2354,3382,252,2506,3104,2040,160,87,2511,113,1863,628,516,2423,340,202,2492,3377,305,221,2765,3024,2025
|
1.2325569767034361,-0.9306276139125141,1.904751655596212,-0.971515740451046,-0.6153265492951593,3.0603364192521147,0.41529180787632924,1.4151493408700357,1.4279535786684734,0.09468784334280253,1.402314093228658,-0.558403728184664,1.6777690135569574,2.9065277890482055,2.4918352621956807,-0.40974773902190176,-2.0753063910430853,1.4915153034770001,-0.5208177336190014,-1.0543430004362901,-0.24767692023999524,1.8695432160167267,2.321161071650228,-0.5208177336190014,2.167327425815136,-0.15986707294579158,0.7022834886797121,0.8756421363992508,-0.4464943548499513,1.2590315225380515,1.7142527679704935,-0.5021316919187672,-1.9981963448778324,1.3506596827179598,1.6287336796515217,-0.7116898323792509,-0.9510285615071858,-0.22999085661134913
| 3,430
|
Sensorimotor neuropathy
| 9
| 30
| 3.250198
| 0.001153
|
Q15120,P07602,P03886,O15270,Q9NZJ7,Q9Y2R0,Q9NR77,O60313,P00403
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
389,38,73,295,341,19,123,375,28
|
1559,295,375,414,28,73,607,1254,38,1569,3062,1074,948,2361,1194,2387,2510,2045,1335,389,1494,1524,3055,2243,123,1903,2102,341,19,1025
|
-0.02250118346835699,1.3636206339195902,1.1657819605638418,1.07084676596474,3.0698107589013315,2.4178172840822203,0.7169539114401163,0.1604504658814682,3.0127233121243298,-0.02250118346835699,-1.0127520150653435,0.2735187641595761,0.36847097049977656,-0.40974773902190176,0.19301386899346543,-0.4280869276823581,-0.5208177336190014,-0.24767692023999524,0.11120892157867891,1.1388325289942267,0.02805701137235168,0.01126068031324202,-0.992089953515064,-0.33706243340680064,2.077431989617715,-0.1773059016141884,-0.26542599868242417,1.2590315225380515,3.2192694624153164,0.32121625895525563
| 3,430
|
Abnormal muscle fiber morphology
| 19
| 70
| 3.211535
| 0.00132
|
P61978,Q70HW3,O43676,Q99720,P00403,O95831,P23786,P50402,Q9H2D1,P31483,P03886,P05067,P51114,P22626,P12235,Q96RL7,P35637,O14979,O60313
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
387,16,21,26,28,414,33,431,49,322,73,205,84,343,213,358,235,108,375
|
1950,108,21,2217,375,1875,1356,444,414,1443,28,1534,73,3319,205,2819,1254,2548,981,1255,213,1475,2859,343,33,1747,322,3167,235,3234,585,775,431,1192,84,1100,2483,2387,387,1296,2608,1670,2298,3275,651,1676,16,1897,2302,2274,920,2565,1043,358,937,26,1325,1087,1212,49,3424,850,1089,2132,2712,1350,3241,1025,2815,1698
|
-0.2123673195994045,2.1784605959005607,3.200802504118346,-0.33706243340680064,1.1657819605638418,-0.1773059016141884,0.09468784334280253,1.001966258000303,1.07084676596474,0.04479749007284595,3.0698107589013315,-0.005591913085313469,2.4178172840822203,-1.6071712099891131,1.6777690135569574,-0.7704316844994457,0.1604504658814682,-0.558403728184664,0.33701658189477507,0.1604504658814682,1.641034754600386,0.02805701137235168,-0.8099892376198776,1.2458108826688405,3.0318170762153325,-0.10791253841717666,1.2853737321434007,-1.1599171531024435,1.5667994320520733,-1.3117306703903504,0.7461703883999292,0.5380910558331444,1.0296274822176772,0.19301386899346543,2.3319852246797077,0.25751962221115077,-0.5021316919187672,-0.4280869276823581,1.1388325289942267,0.14408985151272588,-0.596278947334594,-0.07357327446040215,-0.373271876429598,-1.445808727840182,0.6728169776242082,-0.07357327446040215,3.2651743542921823,-0.1773059016141884,-0.373271876429598,-0.35513411913799386,0.3997325317718629,-0.558403728184664,0.30536674022651894,1.2192696206606266,0.3841256925736641,3.107549151128594,0.1276761298241045,0.2735187641595761,0.19301386899346543,2.7383268943293446,-4.1411192303358,0.4616874064468927,0.2735187641595761,-0.2832385860448953,-0.6729168790091554,0.11120892157867891,-1.3117306703903504,0.32121625895525563,-0.7507725016906376,-0.07357327446040215
| 3,430
|
Abnormality of the mitochondrion
| 24
| 93
| 3.206687
| 0.001343
|
P51970,P11177,Q96CU9,Q9UBX3,Q7KZN9,Q70HW3,Q9Y2R0,O43676,P00403,Q9P0J0,O75306,P23786,Q86Y39,Q9Y6M9,Q9NPL8,O75648,P03886,P13073,Q00325,P12235,O43772,P35637,Q4J6C6,Q9Y584
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
386,509,274,13,525,16,19,21,28,158,413,33,168,326,325,444,73,336,214,213,468,235,371,119
|
892,1948,1559,1950,21,2922,468,1441,413,978,1442,444,1029,2033,606,28,73,2035,1568,2924,509,3358,213,336,3028,2639,1119,693,1997,33,1851,3031,3011,1747,235,2926,3168,948,1395,2507,775,1258,3152,2079,386,2669,2483,2623,2387,695,214,1968,2418,2995,533,1673,625,968,1893,371,651,2092,2786,16,525,2302,2846,168,1493,935,2565,1459,274,1044,1865,937,1837,1325,2518,1408,816,1089,325,749,158,3124,13,2712,19,2616,1025,119,326
|
0.41529180787632924,-0.2123673195994045,-0.02250118346835699,-0.2123673195994045,3.200802504118346,-0.8699343008139493,0.9462000577616902,0.04479749007284595,1.07084676596474,0.33701658189477507,0.04479749007284595,1.001966258000303,0.30536674022651894,-0.24767692023999524,0.7169539114401163,3.0698107589013315,2.4178172840822203,-0.24767692023999524,-0.02250118346835699,-0.8699343008139493,0.8756421363992508,-1.8477085071425041,1.641034754600386,1.2590315225380515,-0.971515740451046,-0.6344483133432426,0.24146991514915547,0.6282990804246098,-0.22999085661134913,3.0318170762153325,-0.15986707294579158,-0.971515740451046,-0.9510285615071858,-0.10791253841717666,1.5667994320520733,-0.8699343008139493,-1.1599171531024435,0.36847097049977656,0.07811250742307049,-0.5208177336190014,0.5380910558331444,0.1604504658814682,-1.1386163266404463,-0.26542599868242417,1.1388325289942267,-0.6536448751928122,-0.5021316919187672,-0.6153265492951593,-0.4280869276823581,0.6282990804246098,1.641034754600386,-0.2123673195994045,-0.4464943548499513,-0.9306276139125141,0.8328430643605732,-0.07357327446040215,0.7022834886797121,0.3527680424371989,-0.1773059016141884,1.179204988513675,0.6728169776242082,-0.26542599868242417,-0.7311921139115007,3.2651743542921823,0.861414936766202,-0.373271876429598,-0.7901703605422196,1.8459424393187207,0.02805701137235168,0.3841256925736641,-0.558403728184664,0.04479749007284595,1.4279535786684734,0.30536674022651894,-0.15986707294579158,0.3841256925736641,-0.1424888753229872,0.1276761298241045,-0.5208177336190014,0.07811250742307049,0.4923857069491886,0.2735187641595761,1.2853737321434007,0.5833929390939195,1.8813049364421908,-1.075273613042021,3.391761695054266,-0.6729168790091554,3.2192694624153164,-0.596278947334594,0.32121625895525563,2.1113172784145564,1.2853737321434007
| 3,430
|
Functional abnormality of the gastrointestinal tract
| 61
| 288
| 3.205254
| 0.001349
|
O75874,P61978,O14678,P61916,P48735,O15460,Q13045,P51571,P06280,O95202,Q01844,Q99720,P21964,Q9UGP8,P04062,P00403,O75306,P08183,O15269,Q12768,P07602,O15270,Q9Y619,Q9Y4P3,Q9NZ08,Q14108,Q96D71,Q15067,Q6NUK1,P04350,P42858,P55011,P55795,P42892,P03886,Q06787,P05067,P15586,Q9NZJ7,Q99519,Q96PU5,O96028,O75569,P12235,Q8IZA0,Q14739,O76024,Q96RL7,P16435,Q6PGP7,Q6ZXV5,P35637,Q5HYI8,O15118,P01889,Q9UHX1,Q9Y584,Q96A33,Q13510,Q9NR77,O60313
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
1,387,257,512,10,398,531,403,275,401,282,26,280,547,30,28,413,159,286,550,38,295,45,313,185,60,582,319,580,445,447,574,196,69,73,203,205,206,341,340,211,334,342,213,93,222,477,358,231,480,233,235,491,109,369,118,119,379,250,123,375
|
1472,2026,1559,2346,977,257,1438,109,1663,286,295,2318,398,2174,3060,2350,1142,2283,375,1473,2594,2409,870,1875,413,1442,342,1,477,2070,2947,1777,2179,401,1993,1810,1565,2743,1414,334,28,3027,2618,369,73,30,445,1877,205,275,2819,38,2596,2286,159,2597,2035,2431,1255,1535,2856,213,1536,206,1743,231,1444,3010,1996,896,1956,1569,1446,3191,3127,2073,693,280,3163,2355,1393,738,3031,2800,2576,1747,1813,3361,1190,2775,235,657,2413,647,804,1572,2078,2748,2228,2111,3051,2000,1961,1395,447,69,585,2001,2749,10,677,796,2967,1258,1163,1363,403,2509,805,1100,2483,986,2670,2326,1713,821,574,2387,1290,196,1544,2327,2862,512,387,3034,2902,1815,1366,2879,695,1576,1333,2484,1783,1334,282,1450,1817,2934,1296,807,3054,1165,3295,2511,2608,2674,203,2045,550,1857,531,2418,2626,250,1228,60,1485,2298,2113,222,2299,319,1821,1078,1126,2439,2996,2905,2440,3185,1673,491,3108,2676,2725,2051,580,2976,480,2610,698,2845,233,1424,1171,824,1897,2563,1064,2274,1796,93,933,1493,2010,1206,2276,1040,2680,2197,2395,1523,2306,1524,2729,2422,2338,1834,1269,1378,379,1624,582,1209,2732,685,2758,211,3158,358,937,2312,885,340,1837,26,2123,2124,1325,1463,2518,1241,904,2279,3231,1180,1048,3188,849,2735,2370,1409,1067,1089,2521,123,1764,1346,1903,1022,2101,185,2102,341,1092,1529,632,975,2737,955,547,118,866,708,3097,1598,2139,2066,1216,2024,3213,313,1025,119,2815,45
|
0.02805701137235168,-0.24767692023999524,-0.02250118346835699,-0.40974773902190176,0.33701658189477507,1.4661818634308703,0.04479749007284595,2.1784605959005607,-0.07357327446040215,1.3894476706931538,1.3636206339195902,-0.3914762369552328,1.1117439633053623,-0.31905629408571334,-1.0127520150653435,-0.40974773902190176,0.22536929144369766,-0.373271876429598,1.1657819605638418,0.02805701137235168,-0.596278947334594,-0.4464943548499513,0.43080383738421585,-0.1773059016141884,1.07084676596474,0.04479749007284595,1.2458108826688405,3.92901774642917,0.9321647887240839,-0.26542599868242417,-0.8900812583352817,-0.12517084870498654,-0.31905629408571334,1.0981470112960925,-0.22999085661134913,-0.1424888753229872,-0.02250118346835699,-0.7116898323792509,0.06148252180205109,1.2590315225380515,3.0698107589013315,-0.971515740451046,-0.6153265492951593,1.179204988513675,2.4178172840822203,3.0603364192521147,1.001966258000303,-0.1773059016141884,1.6777690135569574,1.4151493408700357,-0.7704316844994457,3.0127233121243298,-0.596278947334594,-0.373271876429598,1.8695432160167267,-0.596278947334594,-0.24767692023999524,-0.4649705794159142,0.1604504658814682,-0.005591913085313469,-0.8099892376198776,1.641034754600386,-0.005591913085313469,1.6777690135569574,-0.10791253841717666,1.5792439505261,0.04479749007284595,-0.9510285615071858,-0.22999085661134913,0.41529180787632924,-0.2123673195994045,-0.02250118346835699,0.04479749007284595,-1.2028041638743916,-1.096295452188383,-0.26542599868242417,0.6282990804246098,1.402314093228658,-1.1599171531024435,-0.40974773902190176,0.07811250742307049,0.5833929390939195,-0.971515740451046,-0.7507725016906376,-0.5773048800496771,-0.10791253841717666,-0.1424888753229872,-1.8724550432014597,0.19301386899346543,-0.7311921139115007,1.5667994320520733,0.65802036299361,-0.4464943548499513,0.6728169776242082,0.4923857069491886,-0.02250118346835699,-0.26542599868242417,-0.7116898323792509,-0.33706243340680064,-0.2832385860448953,-0.992089953515064,-0.22999085661134913,-0.2123673195994045,0.07811250742307049,1.001966258000303,2.4496613605694386,0.7461703883999292,-0.22999085661134913,-0.7116898323792509,3.454011813127605,0.6431811538013191,0.5076661391022604,-0.9103121062691136,0.1604504658814682,0.20921739577808898,0.09468784334280253,1.0981470112960925,-0.5208177336190014,0.4923857069491886,0.25751962221115077,-0.5021316919187672,0.33701658189477507,-0.6536448751928122,-0.3914762369552328,-0.0907134950668146,0.47705956297724367,0.7607169539788241,-0.4280869276823581,0.14408985151272588,1.738437938975464,-0.005591913085313469,-0.3914762369552328,-0.8099892376198776,0.8756421363992508,1.1388325289942267,-0.971515740451046,-0.8498704751461239,-0.1424888753229872,0.09468784334280253,-0.8298890333091614,0.6282990804246098,-0.02250118346835699,0.11120892157867891,-0.5021316919187672,-0.12517084870498654,0.11120892157867891,1.402314093228658,0.04479749007284595,-0.1424888753229872,-0.8699343008139493,0.14408985151272588,0.4923857069491886,-0.992089953515064,0.20921739577808898,-1.5142922206614813,-0.5208177336190014,-0.596278947334594,-0.6536448751928122,1.7021191193583658,-0.24767692023999524,0.8041129767098191,-0.15986707294579158,0.8471486580863727,-0.4464943548499513,-0.6153265492951593,1.5041368739934033,0.17675834803240076,2.5336885717746562,0.02805701137235168,-0.373271876429598,-0.2832385860448953,1.6164042064007391,-0.373271876429598,1.2984956621256847,-0.1424888753229872,0.2735187641595761,0.24146991514915547,-0.4649705794159142,-0.9306276139125141,-0.8498704751461239,-0.4649705794159142,-1.1813127889529935,-0.07357327446040215,0.9180915884762,-1.0543430004362901,-0.6536448751928122,-0.6922649775615227,-0.24767692023999524,0.7607169539788241,-0.9103121062691136,0.9321647887240839,-0.596278947334594,0.6282990804246098,-0.7901703605422196,1.5792439505261,0.06148252180205109,0.20921739577808898,0.47705956297724367,-0.1773059016141884,-0.558403728184664,0.2894676887918951,-0.35513411913799386,-0.12517084870498654,2.2667166943530197,0.3841256925736641,0.02805701137235168,-0.22999085661134913,0.19301386899346543,-0.35513411913799386,0.30536674022651894,-0.6536448751928122,-0.31905629408571334,-0.4280869276823581,0.01126068031324202,-0.373271876429598,0.01126068031324202,-0.6922649775615227,-0.4464943548499513,-0.3914762369552328,-0.1424888753229872,0.1604504658814682,0.09468784334280253,1.1657819605638418,-0.03946755021715677,0.7607169539788241,0.19301386899346543,-0.6922649775615227,0.6431811538013191,-0.7116898323792509,1.6655522802639968,-1.1386163266404463,1.2192696206606266,0.3841256925736641,-0.373271876429598,0.43080383738421585,1.2590315225380515,-0.1424888753229872,3.107549151128594,-0.2832385860448953,-0.2832385860448953,0.1276761298241045,0.04479749007284595,-0.5208177336190014,0.17675834803240076,0.41529180787632924,-0.35513411913799386,-1.289746149293953,0.20921739577808898,0.30536674022651894,-1.1813127889529935,0.4616874064468927,-0.6922649775615227,-0.40974773902190176,0.07811250742307049,0.2894676887918951,0.2735187641595761,-0.5208177336190014,2.077431989617715,-0.10791253841717666,0.11120892157867891,-0.1773059016141884,0.32121625895525563,-0.26542599868242417,1.774512395985724,-0.26542599868242417,1.2590315225380515,0.2735187641595761,0.01126068031324202,0.7022834886797121,0.3527680424371989,-0.6922649775615227,0.36847097049977656,0.8184979173823138,2.1113172784145564,0.44626893355334946,0.6282990804246098,-1.0335027512907717,-0.02250118346835699,-0.2832385860448953,-0.24767692023999524,0.19301386899346543,-0.22999085661134913,-1.2460779206914567,1.3246420617522143,0.32121625895525563,2.1113172784145564,-0.7507725016906376,2.7982738550861823
| 3,430
|
Protein insertion into membrane
| 14
| 29
| 3.201974
| 0.001365
|
P46379,Q9Y5J9,O14737,Q9NS69,Q96A33,O43681,Q9Y512,Q15070,Q15629,Q9Y5J7,Q9Y584,Q9P0J0,Q9Y5L4,P07900
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
256,193,165,7,379,553,278,181,116,571,119,158,125,656
|
165,553,1809,1098,656,2505,3218,256,1014,988,1618,181,116,951,790,1586,1426,1236,379,703,7,2446,158,1350,278,119,571,193,125
|
1.8459424393187207,0.7896879996375533,-0.1424888753229872,0.25751962221115077,0.65802036299361,-0.5208177336190014,-1.267862233870033,1.47886368568901,0.32121625895525563,0.33701658189477507,-0.03946755021715677,1.7864835322979642,2.133790611209967,0.36847097049977656,0.522901157152449,-0.02250118346835699,0.06148252180205109,0.17675834803240076,1.1657819605638418,0.6282990804246098,3.602417135580486,-0.4649705794159142,1.8813049364421908,0.11120892157867891,1.4151493408700357,2.1113172784145564,0.7752227411673067,1.750489731196436,2.066089721766653
| 3,430
|
Abnormal retinal artery morphology
| 10
| 22
| 3.199408
| 0.001377
|
P17900,P10619,P07602,P03886,P16278,Q9NZJ7,P06865,Q9Y4P3,Q13510,P21964
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
66,226,38,73,43,341,268,313,250,280
|
1472,1439,2350,73,268,38,1358,226,2878,43,66,280,2775,2670,2879,250,2299,2422,340,341,866,313
|
0.02805701137235168,0.04479749007284595,-0.40974773902190176,2.4178172840822203,1.4279535786684734,3.0127233121243298,0.09468784334280253,1.6040461907838122,-0.8298890333091614,2.9065277890482055,2.4918352621956807,1.402314093228658,-0.7311921139115007,-0.6536448751928122,-0.8298890333091614,1.5041368739934033,-0.373271876429598,-0.4464943548499513,1.2590315225380515,1.2590315225380515,0.44626893355334946,1.3246420617522143
| 3,430
|
Electron transport
| 20
| 46
| 3.192855
| 0.001409
|
P51970,Q96CU9,O43169,O95168,O43676,Q16134,O14949,P00403,Q9P0J0,O75306,Q86Y39,P08574,O75438,Q9H1E5,O95864,Q9Y6M9,P03886,Q9UDW1,Q6DKK2,O96000
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
386,274,14,529,21,533,155,28,158,413,168,296,671,171,554,326,73,74,82,606
|
892,1950,155,14,1311,21,2922,1441,413,978,671,1442,529,3008,2033,554,606,28,73,296,3028,3331,2639,693,1997,984,3031,1747,784,3168,1075,3152,386,533,3131,1673,2784,82,168,274,1499,171,831,158,74,326
|
0.41529180787632924,-0.2123673195994045,1.8813049364421908,3.3468758304359083,0.1276761298241045,3.200802504118346,-0.8699343008139493,0.04479749007284595,1.07084676596474,0.33701658189477507,0.6431811538013191,0.04479749007284595,0.8471486580863727,-0.9510285615071858,-0.24767692023999524,0.7896879996375533,0.7169539114401163,3.0698107589013315,2.4178172840822203,1.3636206339195902,-0.971515740451046,-1.6780491319681583,-0.6344483133432426,0.6282990804246098,-0.22999085661134913,0.33701658189477507,-0.971515740451046,-0.10791253841717666,0.522901157152449,-1.1599171531024435,0.2735187641595761,-1.1386163266404463,1.1388325289942267,0.8328430643605732,-1.096295452188383,-0.07357327446040215,-0.7311921139115007,2.342788021416518,1.8459424393187207,1.4279535786684734,0.02805701137235168,1.8459424393187207,0.47705956297724367,1.8813049364421908,2.4178172840822203,1.2853737321434007
| 3,430
|
Abnormal circulating lipid concentration
| 22
| 80
| 3.189365
| 0.001426
|
P61916,P06280,Q15392,Q8N511,O75844,P23786,P07602,P37268,P50402,P22830,Q9Y4P3,Q9NVI7,P42858,O75648,Q9NZJ7,O75845,O95470,Q15800,O43772,Q14739,Q15904,Q96MF7
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
512,275,23,25,32,33,38,166,431,438,313,443,447,444,341,470,86,88,468,222,490,507
|
1438,781,2350,468,1056,1010,444,32,470,1029,86,1534,275,1566,38,1568,3358,438,33,2287,897,928,2775,1224,2926,166,2183,739,948,447,2778,677,1258,431,1058,2079,3310,1194,2462,2510,1195,512,2879,1450,1227,1968,875,531,3071,1670,222,2299,23,1169,88,490,625,1893,1620,3313,25,2395,1043,1524,1378,507,2759,1087,816,443,341,632,866,708,1599,1808,313,3043,2815,3176
|
0.04479749007284595,0.522901157152449,-0.40974773902190176,0.9462000577616902,0.2894676887918951,0.32121625895525563,1.001966258000303,3.050846065270086,0.9462000577616902,0.30536674022651894,2.321161071650228,-0.005591913085313469,1.4151493408700357,-0.02250118346835699,3.0127233121243298,-0.02250118346835699,-1.8477085071425041,1.0158151806848401,3.0318170762153325,-0.373271876429598,0.41529180787632924,0.3841256925736641,-0.7311921139115007,0.17675834803240076,-0.8699343008139493,1.8459424393187207,-0.31905629408571334,0.5833929390939195,0.36847097049977656,1.001966258000303,-0.7311921139115007,0.6431811538013191,0.1604504658814682,1.0296274822176772,0.2894676887918951,-0.26542599868242417,-1.5605037593216007,0.19301386899346543,-0.4835161673691688,-0.5208177336190014,0.19301386899346543,0.8756421363992508,-0.8298890333091614,0.04479749007284595,0.17675834803240076,-0.2123673195994045,0.43080383738421585,0.8471486580863727,-1.0127520150653435,-0.07357327446040215,1.6164042064007391,-0.373271876429598,3.1543688124281597,0.20921739577808898,2.310315469590055,0.9180915884762,0.7022834886797121,-0.1773059016141884,-0.03946755021715677,-1.5605037593216007,3.1263237819839285,-0.4280869276823581,0.30536674022651894,0.01126068031324202,0.09468784334280253,0.8898304908049921,-0.7116898323792509,0.2735187641595761,0.4923857069491886,1.0158151806848401,1.2590315225380515,0.7022834886797121,0.44626893355334946,0.6282990804246098,-0.02250118346835699,-0.12517084870498654,1.3246420617522143,-0.971515740451046,-0.7507725016906376,-1.1599171531024435
| 3,430
|
Talipes equinovarus
| 24
| 81
| 3.179202
| 0.001477
|
P61978,Q8TB36,O95202,Q15907,Q15392,P98175,P21964,P08236,P49902,Q9Y619,Q9Y487,Q9NWM8,Q15427,Q6NUQ1,Q9UL01,Q96L58,O75845,O96028,Q96AY3,P16435,Q6ZXV5,Q96A33,Q9NR77,O60568
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
387,390,401,276,23,281,280,279,160,45,175,179,312,452,79,339,470,334,357,231,233,379,123,376
|
1472,2107,977,2816,3060,2217,376,2574,470,2947,401,334,2225,2819,279,1145,1255,231,1880,3127,280,2800,2149,2748,2620,1710,1961,160,2079,1194,2821,2670,821,387,281,1198,1296,2703,2045,2626,2234,542,23,312,276,1756,452,233,3017,1040,1079,920,482,390,639,2872,3261,2422,379,357,3055,339,1657,2279,1730,1067,123,179,79,2875,855,668,2139,2170,1436,175,2741,2281,891,3388,45
|
0.02805701137235168,-0.2832385860448953,0.33701658189477507,-0.7704316844994457,-1.0127520150653435,-0.33706243340680064,1.1657819605638418,-0.5773048800496771,0.9462000577616902,-0.8900812583352817,1.0981470112960925,1.2590315225380515,-0.33706243340680064,-0.7704316844994457,1.402314093228658,0.22536929144369766,0.1604504658814682,1.5792439505261,-0.1773059016141884,-1.096295452188383,1.402314093228658,-0.7507725016906376,-0.30111518243997987,-0.7116898323792509,-0.6153265492951593,-0.0907134950668146,-0.2123673195994045,1.8695432160167267,-0.26542599868242417,0.19301386899346543,-0.7704316844994457,-0.6536448751928122,0.47705956297724367,1.1388325289942267,1.402314093228658,0.19301386899346543,0.14408985151272588,-0.6729168790091554,-0.24767692023999524,-0.6153265492951593,-0.33706243340680064,0.8184979173823138,3.1543688124281597,1.3246420617522143,1.4151493408700357,-0.10791253841717666,0.98808050071691,1.5792439505261,-0.9510285615071858,0.30536674022651894,0.2735187641595761,0.3997325317718629,0.9321647887240839,1.1388325289942267,0.6875712647067221,-0.8099892376198776,-1.3782981393570042,-0.4464943548499513,1.1657819605638418,1.2192696206606266,-0.992089953515064,1.2590315225380515,-0.0564914375226667,-0.35513411913799386,-0.0907134950668146,0.2894676887918951,2.077431989617715,1.798428045397234,2.3750691920218543,-0.8099892376198776,0.4616874064468927,0.65802036299361,-0.2832385860448953,-0.30111518243997987,0.06148252180205109,1.8103460646896083,-0.6922649775615227,-0.35513411913799386,0.43080383738421585,-2.1012974711813244,2.7982738550861823
| 3,430
|
Glycoprotein metabolic process
| 25
| 62
| 3.178059
| 0.001483
|
Q7LGA3,O14734,O60512,O60502,Q9H0U3,Q2TAA5,Q16706,Q8N4A0,P46977,Q9Y287,Q86YN1,Q10472,Q9UL01,Q96L58,Q9NQX7,Q92542,O60476,O60762,Q6ZXV5,Q9BT22,P04844,O15118,Q8NAT1,P35610,O60568
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
128,391,18,147,536,288,551,172,430,190,453,456,79,339,225,612,227,605,233,494,362,109,115,252,376
|
2107,977,391,109,2767,752,837,227,147,18,376,2546,605,2220,1356,2743,872,362,1536,1190,252,2228,430,2836,2004,2484,1296,2608,914,875,456,1646,1484,1202,551,288,233,128,1723,453,172,115,628,612,2849,339,3387,1628,494,536,2206,1138,748,3424,850,225,1246,1556,2687,79,190,1698
|
-0.2832385860448953,0.33701658189477507,1.125305736257329,2.1784605959005607,-0.7311921139115007,0.5683366593475094,0.4616874064468927,1.5916594876052144,1.904751655596212,3.237676205824806,1.1657819605638418,-0.558403728184664,0.7169539114401163,-0.33706243340680064,0.09468784334280253,-0.7116898323792509,0.43080383738421585,1.1925938145223307,-0.005591913085313469,0.19301386899346543,1.4915153034770001,-0.33706243340680064,1.0296274822176772,-0.7901703605422196,-0.22999085661134913,-0.5021316919187672,0.14408985151272588,-0.596278947334594,0.3997325317718629,0.43080383738421585,0.9741576934609325,-0.0564914375226667,0.02805701137235168,0.19301386899346543,0.8041129767098191,1.3894476706931538,1.5792439505261,2.0547236877093185,-0.0907134950668146,0.98808050071691,1.8341031346457968,2.156171440265243,0.7022834886797121,0.7169539114401163,-0.7901703605422196,1.2590315225380515,-2.1012974711813244,-0.03946755021715677,0.9180915884762,0.8328430643605732,-0.31905629408571334,0.24146991514915547,0.5833929390939195,-4.1411192303358,0.4616874064468927,1.6164042064007391,0.17675834803240076,-0.005591913085313469,-0.6536448751928122,2.3750691920218543,1.7625145060761207,-0.07357327446040215
| 3,430
|
Secondary active transmembrane transporter activity
| 13
| 19
| 3.16877
| 0.001531
|
P12236,Q02978,Q96ES6,P55011,P51798,Q9UBX3,P53985,Q9BXP2,O95202,Q00325,P12235,Q9Y6M7,Q15043
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
418,696,37,574,524,13,271,601,401,214,213,548,191
|
401,736,1567,213,418,524,1100,271,574,214,696,191,950,1130,37,601,1409,13,548
|
1.0981470112960925,0.5833929390939195,-0.02250118346835699,1.641034754600386,1.057143066123191,0.861414936766202,0.25751962221115077,1.4279535786684734,0.7607169539788241,1.641034754600386,0.6282990804246098,1.750489731196436,0.36847097049977656,0.24146991514915547,3.0222783212407616,0.7315827923762055,0.07811250742307049,3.391761695054266,0.8184979173823138
| 3,430
|
Hormone metabolic process
| 9
| 29
| 3.164931
| 0.001551
|
O75844,P30536,P42892,P16435,Q9HB40,Q06520,Q6NUM9,O95470,Q14849
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
32,2,69,231,40,144,216,86,27
|
2256,32,3338,86,607,2148,3141,231,2,740,69,3169,1194,2081,2556,144,27,2190,262,216,1207,1623,1175,1499,1837,40,632,3097,768
|
-0.35513411913799386,3.050846065270086,-1.725900749051077,2.321161071650228,0.7169539114401163,-0.30111518243997987,-1.117409393747407,1.5792439505261,3.92901774642917,0.5833929390939195,2.4496613605694386,-1.1599171531024435,0.19301386899346543,-0.26542599868242417,-0.558403728184664,1.9513415899455118,3.0792691433168833,-0.31905629408571334,1.4534696782308594,1.641034754600386,0.19301386899346543,-0.03946755021715677,0.20921739577808898,0.02805701137235168,-0.1424888753229872,2.983960149974089,0.7022834886797121,-1.0335027512907717,0.5532361269354006
| 3,430
|
Limitation of joint mobility
| 27
| 103
| 3.153004
| 0.001616
|
Q7LGA3,O75874,P48735,O15460,Q13045,P08236,O75844,P23786,P37268,P16278,P50402,Q15427,Q9Y4P3,P15586,Q96L58,Q13535,P54802,Q8TAA9,Q96AY3,O76024,P16435,P48651,P51648,O14979,Q9BT22,P01889,O60568
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
128,1,10,398,531,279,32,33,166,43,431,312,313,206,339,338,87,482,357,477,231,360,110,108,494,369,376
|
1389,2107,977,2816,1026,108,3322,398,3060,2350,837,2283,376,2594,2284,2574,1010,2145,32,1,477,2070,1777,927,369,1534,2819,279,1954,1255,206,43,231,896,3127,2859,33,2800,1813,1190,2775,166,3234,360,10,431,2509,110,87,821,2387,2879,1450,1296,2703,741,1165,2556,2045,3296,531,338,1670,3275,2113,2091,542,1488,2299,312,2051,128,1206,1040,482,2565,639,2872,1523,1043,3346,2120,1834,1624,357,2308,685,339,2312,2124,494,1087,2279,1730,1944,2521,866,2066,2712,2170,1470,313,1847
|
0.07811250742307049,-0.2832385860448953,0.33701658189477507,-0.7704316844994457,0.30536674022651894,2.1784605959005607,-1.6306790060749776,1.1117439633053623,-1.0127520150653435,-0.40974773902190176,0.4616874064468927,-0.373271876429598,1.1657819605638418,-0.596278947334594,-0.373271876429598,-0.5773048800496771,0.32121625895525563,-0.30111518243997987,3.050846065270086,3.92901774642917,0.9321647887240839,-0.26542599868242417,-0.12517084870498654,0.3841256925736641,1.179204988513675,-0.005591913085313469,-0.7704316844994457,1.402314093228658,-0.2123673195994045,0.1604504658814682,1.6777690135569574,2.9065277890482055,1.5792439505261,0.41529180787632924,-1.096295452188383,-0.8099892376198776,3.0318170762153325,-0.7507725016906376,-0.1424888753229872,0.19301386899346543,-0.7311921139115007,1.8459424393187207,-1.3117306703903504,1.2059486289837344,3.454011813127605,1.0296274822176772,-0.5208177336190014,2.1784605959005607,2.321161071650228,0.47705956297724367,-0.4280869276823581,-0.8298890333091614,0.04479749007284595,0.14408985151272588,-0.6729168790091554,0.5833929390939195,0.20921739577808898,-0.558403728184664,-0.24767692023999524,-1.5142922206614813,0.8471486580863727,1.2590315225380515,-0.07357327446040215,-1.445808727840182,-0.2832385860448953,-0.26542599868242417,0.8184979173823138,0.02805701137235168,-0.373271876429598,1.3246420617522143,-0.24767692023999524,2.0547236877093185,0.19301386899346543,0.30536674022651894,0.9321647887240839,-0.558403728184664,0.6875712647067221,-0.8099892376198776,0.01126068031324202,0.30536674022651894,-1.7500104946959263,-0.2832385860448953,-0.1424888753229872,-0.03946755021715677,1.2192696206606266,-0.373271876429598,0.6431811538013191,1.2590315225380515,-0.373271876429598,-0.2832385860448953,0.9180915884762,0.2735187641595761,-0.35513411913799386,-0.0907134950668146,-0.1948058268211105,-0.5208177336190014,0.44626893355334946,-0.24767692023999524,-0.6729168790091554,-0.30111518243997987,0.04479749007284595,1.3246420617522143,-0.1424888753229872
| 3,430
|
Arthritis
| 12
| 43
| 3.118585
| 0.001817
|
O75844,Q96RL7,P10321,P01889,P06280,Q96HY6,Q9NZ08,Q13510,P21964,Q14108,Q14739,P04062
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
32,358,393,369,275,380,185,250,280,60,222,30
|
2173,1472,398,3248,32,2618,369,1534,30,275,2548,393,3046,1223,280,2859,2287,796,1363,1612,524,1712,2670,1290,1014,1450,2511,250,60,222,2091,822,2302,996,2422,380,358,1138,185,750,1470,2025,3213
|
-0.31905629408571334,0.02805701137235168,1.1117439633053623,-1.3560056220962575,3.050846065270086,-0.6153265492951593,1.179204988513675,-0.005591913085313469,3.0603364192521147,1.4151493408700357,-0.558403728184664,1.125305736257329,-0.992089953515064,0.17675834803240076,1.402314093228658,-0.8099892376198776,-0.373271876429598,0.5076661391022604,0.09468784334280253,-0.03946755021715677,0.861414936766202,-0.0907134950668146,-0.6536448751928122,0.14408985151272588,0.32121625895525563,0.04479749007284595,-0.5208177336190014,1.5041368739934033,2.5336885717746562,1.6164042064007391,-0.26542599868242417,0.47705956297724367,-0.373271876429598,0.33701658189477507,-0.4464943548499513,1.1657819605638418,1.2192696206606266,0.24146991514915547,1.774512395985724,0.5833929390939195,0.04479749007284595,-0.22999085661134913,-1.2460779206914567
| 3,430
|
Abnormality of coordination
| 61
| 332
| 3.117214
| 0.001826
|
Q9NP80,Q96CU9,O15460,Q13315,O43676,P50897,Q15907,O95202,Q99707,Q99720,O14949,P00403,P04062,Q9P0J0,Q2TAA5,O95831,O14773,O75306,Q10713,P07602,Q86Y39,P16278,Q9Y619,Q9Y487,Q9Y4P3,Q9NZ08,P07437,Q9NVI7,Q14108,Q9Y287,Q15067,P04350,O43292,Q9Y6M9,P55795,Q9NPL8,P31483,P03886,Q06787,P00374,P05067,Q9NZJ7,Q99519,Q6DKK2,O96028,Q5JRX3,O95470,P12235,O60313,Q96RL7,Q6P4A7,O75503,P35637,P14854,O15118,P01889,Q8IV08,Q13510,Q9NR77,P35610,Q14738
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
264,274,398,400,21,22,276,401,284,26,155,28,30,158,288,414,162,413,292,38,168,43,45,175,313,185,310,443,60,190,319,445,194,326,196,325,322,73,203,76,205,341,340,82,334,85,86,213,375,358,232,104,235,363,109,369,120,250,123,252,254
|
892,1948,1559,1950,2346,467,977,162,1438,604,155,794,869,109,2407,398,194,21,2922,553,2350,2817,1142,375,1874,2478,605,1776,763,870,1441,413,1356,978,1056,1532,1442,104,1250,477,1413,2179,401,2033,1810,1565,2743,1414,86,2695,3045,2502,414,606,1443,334,76,28,3027,3330,369,73,30,3349,445,205,2352,2819,1254,3082,310,38,1358,2286,2035,1568,2924,1255,676,509,1222,3358,2856,213,2433,363,2878,983,43,1996,896,1569,1880,2639,1415,2324,1446,2073,693,737,1997,2354,1851,2772,1393,738,3031,3049,3011,3165,1747,322,1478,2775,1074,2110,252,235,657,2926,3068,804,1572,2748,2111,739,948,1961,1395,447,1541,1884,2507,2290,2699,3282,796,2967,2039,2927,3152,2361,2079,3400,22,2509,1963,1194,2669,1100,1713,821,2387,2510,1290,196,1195,2292,512,3034,2555,2879,1034,2529,1783,1198,1334,1015,1227,741,3054,1165,3295,2608,203,292,2045,550,3296,2418,1335,400,2626,3071,250,2235,1670,60,2298,3228,1582,2113,254,1398,2995,2299,319,1821,1078,2996,276,2905,1673,288,1893,85,1262,2157,626,2842,82,2786,232,1104,1235,2610,525,993,1171,1897,994,2563,2654,1795,2846,168,120,1128,933,1493,1494,1206,1040,2680,3355,920,935,1175,2788,1497,1237,1083,2729,1683,2338,526,1176,1378,1685,1000,274,1270,582,1209,1001,2732,972,2758,3055,1657,3158,358,937,2761,2312,2243,1303,885,340,284,1837,26,3001,3135,2124,1463,2518,1212,904,1005,2279,3172,2018,3231,3188,3424,1409,850,264,325,3374,2521,2963,123,1764,443,1984,2101,2133,185,2102,341,749,158,1092,3124,1529,975,3397,2687,1068,866,1845,3097,1349,1695,1350,190,2896,1436,3213,175,1808,313,1847,3043,1025,2741,1698,891,45,326
|
0.41529180787632924,-0.2123673195994045,-0.02250118346835699,-0.2123673195994045,-0.40974773902190176,0.9462000577616902,0.33701658189477507,1.8577557582221775,0.04479749007284595,0.7169539114401163,1.8813049364421908,0.5076661391022604,0.43080383738421585,2.1784605959005607,-0.4464943548499513,1.1117439633053623,1.738437938975464,3.200802504118346,-0.8699343008139493,0.7896879996375533,-0.40974773902190176,-0.7704316844994457,0.22536929144369766,1.1657819605638418,-0.1773059016141884,-0.5021316919187672,0.7169539114401163,-0.12517084870498654,0.5532361269354006,0.43080383738421585,0.04479749007284595,1.07084676596474,0.09468784334280253,0.33701658189477507,0.2894676887918951,-0.005591913085313469,0.04479749007284595,2.189571052524327,0.1604504658814682,0.9321647887240839,0.06148252180205109,-0.31905629408571334,1.0981470112960925,-0.24767692023999524,-0.1424888753229872,-0.02250118346835699,-0.7116898323792509,0.06148252180205109,2.321161071650228,-0.6729168790091554,-0.992089953515064,-0.5208177336190014,1.07084676596474,0.7169539114401163,0.04479749007284595,1.2590315225380515,2.3964848636249685,3.0698107589013315,-0.971515740451046,-1.6780491319681583,1.179204988513675,2.4178172840822203,3.0603364192521147,-1.7986048232476497,1.001966258000303,1.6777690135569574,-0.40974773902190176,-0.7704316844994457,0.1604504658814682,-1.0335027512907717,1.3246420617522143,3.0127233121243298,0.09468784334280253,-0.373271876429598,-0.24767692023999524,-0.02250118346835699,-0.8699343008139493,0.1604504658814682,0.6431811538013191,0.8756421363992508,0.17675834803240076,-1.8477085071425041,-0.8099892376198776,1.641034754600386,-0.4649705794159142,1.1925938145223307,-0.8298890333091614,0.33701658189477507,2.9065277890482055,-0.22999085661134913,0.41529180787632924,-0.02250118346835699,-0.1773059016141884,-0.6344483133432426,0.06148252180205109,-0.3914762369552328,0.04479749007284595,-0.26542599868242417,0.6282990804246098,0.5833929390939195,-0.22999085661134913,-0.40974773902190176,-0.15986707294579158,-0.7311921139115007,0.07811250742307049,0.5833929390939195,-0.971515740451046,-0.992089953515064,-0.9510285615071858,-1.1599171531024435,-0.10791253841717666,1.2853737321434007,0.02805701137235168,-0.7311921139115007,0.2735187641595761,-0.2832385860448953,1.4915153034770001,1.5667994320520733,0.65802036299361,-0.8699343008139493,-1.0127520150653435,0.4923857069491886,-0.02250118346835699,-0.7116898323792509,-0.2832385860448953,0.5833929390939195,0.36847097049977656,-0.2123673195994045,0.07811250742307049,1.001966258000303,-0.005591913085313469,-0.1773059016141884,-0.5208177336190014,-0.373271876429598,-0.6729168790091554,-1.468526945815869,0.5076661391022604,-0.9103121062691136,-0.24767692023999524,-0.8699343008139493,-1.1386163266404463,-0.40974773902190176,-0.26542599868242417,-2.3420518460725406,3.191546309151074,-0.5208177336190014,-0.2123673195994045,0.19301386899346543,-0.6536448751928122,0.25751962221115077,-0.0907134950668146,0.47705956297724367,-0.4280869276823581,-0.5208177336190014,0.14408985151272588,1.738437938975464,0.19301386899346543,-0.373271876429598,0.8756421363992508,-0.971515740451046,-0.558403728184664,-0.8298890333091614,0.30536674022651894,-0.5395748804972572,-0.12517084870498654,0.19301386899346543,0.11120892157867891,0.32121625895525563,0.17675834803240076,0.5833929390939195,-0.992089953515064,0.20921739577808898,-1.5142922206614813,-0.596278947334594,1.7021191193583658,1.3765499068522848,-0.24767692023999524,0.8041129767098191,-1.5142922206614813,-0.4464943548499513,0.11120892157867891,1.1117439633053623,-0.6153265492951593,-1.0127520150653435,1.5041368739934033,-0.33706243340680064,-0.07357327446040215,2.5336885717746562,-0.373271876429598,-1.289746149293953,-0.02250118346835699,-0.2832385860448953,1.4915153034770001,0.07811250742307049,-0.9306276139125141,-0.373271876429598,1.2984956621256847,-0.1424888753229872,0.2735187641595761,-0.9306276139125141,1.4151493408700357,-0.8498704751461239,-0.07357327446040215,1.3894476706931538,-0.1773059016141884,2.3319852246797077,0.1604504658814682,-0.30111518243997987,0.7022834886797121,-0.7901703605422196,2.342788021416518,-0.7311921139115007,1.5792439505261,0.25751962221115077,0.17675834803240076,-0.596278947334594,0.861414936766202,0.33701658189477507,0.20921739577808898,-0.1773059016141884,0.33701658189477507,-0.558403728184664,-0.6344483133432426,-0.12517084870498654,-0.7901703605422196,1.8459424393187207,2.1000456604552045,0.24146991514915547,0.3841256925736641,0.02805701137235168,0.02805701137235168,0.19301386899346543,0.30536674022651894,-0.6536448751928122,-1.8230922651443087,0.3997325317718629,0.3841256925736641,0.20921739577808898,-0.7311921139115007,0.02805701137235168,0.17675834803240076,0.2735187641595761,-0.6922649775615227,-0.07357327446040215,-0.3914762369552328,0.861414936766202,0.20921739577808898,0.09468784334280253,-0.07357327446040215,0.33701658189477507,1.4279535786684734,0.1604504658814682,0.7607169539788241,0.19301386899346543,0.33701658189477507,-0.6922649775615227,0.3527680424371989,-0.7116898323792509,-0.992089953515064,-0.0564914375226667,-1.1386163266404463,1.2192696206606266,0.3841256925736641,-0.7116898323792509,-0.373271876429598,-0.33706243340680064,0.14408985151272588,0.43080383738421585,1.2590315225380515,1.402314093228658,-0.1424888753229872,3.107549151128594,-0.9306276139125141,-1.096295452188383,-0.2832385860448953,0.04479749007284595,-0.5208177336190014,0.19301386899346543,0.41529180787632924,0.33701658189477507,-0.35513411913799386,-1.1599171531024435,-0.22999085661134913,-1.289746149293953,-1.1813127889529935,-4.1411192303358,0.07811250742307049,0.4616874064468927,1.4534696782308594,1.2853737321434007,-1.9727749634114744,-0.5208177336190014,-0.8900812583352817,2.077431989617715,-0.10791253841717666,1.0158151806848401,-0.2123673195994045,-0.26542599868242417,-0.2832385860448953,1.774512395985724,-0.26542599868242417,1.2590315225380515,0.5833929390939195,1.8813049364421908,0.2735187641595761,-1.075273613042021,0.01126068031324202,0.3527680424371989,-2.2874512966961964,-0.6536448751928122,0.2894676887918951,0.44626893355334946,-0.1424888753229872,-1.0335027512907717,0.11120892157867891,-0.07357327446040215,0.11120892157867891,1.7625145060761207,-0.8298890333091614,0.06148252180205109,-1.2460779206914567,1.8103460646896083,-0.12517084870498654,1.3246420617522143,-0.1424888753229872,-0.971515740451046,0.32121625895525563,-0.6922649775615227,-0.07357327446040215,0.43080383738421585,2.7982738550861823,1.2853737321434007
| 3,430
|
Nuclear envelope
| 51
| 180
| 3.105215
| 0.001901
|
Q8TD16,P57088,P80303,Q9HB71,Q86UE4,P67809,O00560,Q5SRE5,Q5SNT2,Q99720,Q8IXM6,O75844,Q15154,Q9P035,Q6ZRP7,Q5BJF2,Q7Z3B4,Q99567,Q9H1E5,Q9H2V7,Q9UH99,P50402,P07437,Q8N201,Q96KC8,P62995,Q9BZF1,O15397,P43243,P05067,Q9NXE4,Q8NFQ8,Q9C0E2,Q99523,Q6NUM9,P41208,Q9BTX1,Q8N1F7,Q14739,P42345,O15173,Q12769,Q9NQC3,Q8NFH4,Q9NUQ2,Q9UBM7,O15118,O94901,P52294,O76062,Q14728
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
639,511,5,654,263,396,266,662,661,26,156,32,543,294,552,299,559,42,171,46,434,431,310,450,324,576,458,328,585,205,591,83,602,600,216,344,92,611,222,353,99,478,359,627,367,632,109,368,117,382,638
|
1737,2852,1248,1908,266,1116,2816,893,2215,109,99,328,3335,1992,1775,2946,2145,2694,979,32,382,368,1251,1534,2717,205,3216,310,2768,2036,2431,1509,1535,1706,2857,947,2900,1446,3048,3064,657,2506,1572,344,786,1148,353,1395,1884,585,2777,1447,3103,1543,1915,862,3362,431,912,117,1033,3105,1418,2080,511,1195,2267,2416,576,1815,396,1966,5,1513,2703,1227,988,3353,478,1422,1200,1785,1485,638,222,1372,2189,543,2905,299,1204,1676,1103,661,662,2486,216,552,559,1678,263,2008,1425,2336,156,1154,611,450,1725,2959,1341,2421,627,83,639,1267,1833,2682,1043,1899,2163,747,903,3000,324,2424,2203,2760,792,1758,600,1939,42,26,1085,2887,1087,92,2961,1981,2912,886,2492,1465,458,602,171,46,3342,941,654,1983,359,1764,2494,367,1434,707,591,2248,3271,294,1734,632,1215,434,1385,3022,1906,2894,1348,2402,1990,1024,1470,2616,2985,1697,2815,1007
|
-0.10791253841717666,-0.8099892376198776,0.1604504658814682,-0.1948058268211105,1.4407269703301229,0.24146991514915547,-0.7704316844994457,0.41529180787632924,-0.33706243340680064,2.1784605959005607,2.211724229893288,1.2722190787348595,-1.701914084340314,-0.22999085661134913,-0.12517084870498654,-0.8900812583352817,-0.30111518243997987,-0.6729168790091554,0.33701658189477507,3.050846065270086,1.1523245386286525,1.179204988513675,0.1604504658814682,-0.005591913085313469,-0.6922649775615227,1.6777690135569574,-1.267862233870033,1.3246420617522143,-0.7311921139115007,-0.24767692023999524,-0.4649705794159142,0.01126068031324202,-0.005591913085313469,-0.0907134950668146,-0.8099892376198776,0.36847097049977656,-0.8498704751461239,0.04479749007284595,-0.992089953515064,-1.0127520150653435,0.65802036299361,-0.5208177336190014,-0.02250118346835699,1.2458108826688405,0.522901157152449,0.22536929144369766,1.2192696206606266,0.07811250742307049,-0.1773059016141884,0.7461703883999292,-0.7311921139115007,0.04479749007284595,-1.0543430004362901,-0.005591913085313469,-0.1948058268211105,0.44626893355334946,-1.8724550432014597,1.0296274822176772,0.3997325317718629,2.1113172784145564,0.30536674022651894,-1.0543430004362901,0.06148252180205109,-0.26542599868242417,0.8756421363992508,0.19301386899346543,-0.35513411913799386,-0.4464943548499513,0.7607169539788241,-0.1424888753229872,1.125305736257329,-0.2123673195994045,3.8304852644801137,0.01126068031324202,-0.6729168790091554,0.17675834803240076,0.33701658189477507,-1.8230922651443087,0.9321647887240839,0.06148252180205109,0.19301386899346543,-0.12517084870498654,0.02805701137235168,0.6875712647067221,1.6164042064007391,0.09468784334280253,-0.31905629408571334,0.8184979173823138,-0.8498704751461239,1.3636206339195902,0.19301386899346543,-0.07357327446040215,0.25751962221115077,0.65802036299361,0.65802036299361,-0.5021316919187672,1.641034754600386,0.8041129767098191,0.7896879996375533,-0.07357327446040215,1.4534696782308594,-0.22999085661134913,0.06148252180205109,-0.3914762369552328,1.8813049364421908,0.22536929144369766,0.7169539114401163,1.001966258000303,-0.0907134950668146,-0.8900812583352817,0.11120892157867891,-0.4464943548499513,0.7022834886797121,2.342788021416518,0.6875712647067221,0.1604504658814682,-0.1424888753229872,-0.6536448751928122,0.30536674022651894,-0.1773059016141884,-0.30111518243997987,0.5833929390939195,0.41529180787632924,-0.9306276139125141,1.2853737321434007,-0.4464943548499513,-0.31905629408571334,-0.7116898323792509,0.522901157152449,-0.10791253841717666,0.7315827923762055,-0.1948058268211105,2.916265686588943,3.107549151128594,0.2735187641595761,-0.8298890333091614,0.2735187641595761,2.277649032464161,-0.8900812583352817,-0.2123673195994045,-0.8498704751461239,0.43080383738421585,-0.5021316919187672,0.04479749007284595,0.9741576934609325,0.7315827923762055,1.8459424393187207,2.7583811399319984,-1.725900749051077,0.3841256925736641,0.6728169776242082,-0.2123673195994045,1.2192696206606266,-0.10791253841717666,-0.5021316919187672,1.1925938145223307,0.06148252180205109,0.6282990804246098,0.7461703883999292,-0.33706243340680064,-1.4231985981949864,1.3765499068522848,-0.0907134950668146,0.7022834886797121,0.19301386899346543,1.0296274822176772,0.09468784334280253,-0.9510285615071858,-0.1773059016141884,-0.8298890333091614,0.11120892157867891,-0.4280869276823581,-0.2123673195994045,0.32121625895525563,0.04479749007284595,-0.596278947334594,-0.9103121062691136,-0.07357327446040215,-0.7507725016906376,0.33701658189477507
| 3,430
|
protein modifying enzyme
| 12
| 26
| 3.101551
| 0.001925
|
O60725,Q15418,Q86YN1,O60476,O14744,O15460,Q6P2P2,P50897,O75718,P13674,Q92791,O60568
|
Functions
|
Panther Protein class
|
panther_protein_class
|
65,354,453,227,461,398,277,22,89,314,219,376
|
2107,461,2767,398,227,376,2256,65,89,314,22,619,2837,1296,2087,2391,354,2754,277,1205,453,1266,219,2278,1138,476
|
-0.2832385860448953,0.9601976189085124,-0.7311921139115007,1.1117439633053623,1.5916594876052144,1.1657819605638418,-0.35513411913799386,2.4918352621956807,2.2994483251380298,1.311585046538852,3.191546309151074,0.7022834886797121,-0.7901703605422196,0.14408985151272588,-0.26542599868242417,-0.4280869276823581,1.2192696206606266,-0.7116898323792509,1.4151493408700357,0.19301386899346543,0.98808050071691,0.1604504658814682,1.6287336796515217,-0.35513411913799386,0.24146991514915547,0.9462000577616902
| 3,430
|
Skin nodule
| 7
| 21
| 3.094272
| 0.001973
|
O75874,P48735,P35637,P16615,P06280,Q9NZ08,Q13510
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
1,10,235,269,275,185,250
|
1874,1,369,858,275,1535,269,693,928,1190,235,10,796,1120,1450,2556,250,2241,1903,185,1470
|
-0.1773059016141884,3.92901774642917,1.179204988513675,0.44626893355334946,1.4151493408700357,-0.005591913085313469,1.4279535786684734,0.6282990804246098,0.3841256925736641,0.19301386899346543,1.5667994320520733,3.454011813127605,0.5076661391022604,0.24146991514915547,0.04479749007284595,-0.558403728184664,1.5041368739934033,-0.33706243340680064,-0.1773059016141884,1.774512395985724,0.04479749007284595
| 3,430
|
Vascular skin abnormality
| 30
| 125
| 3.089958
| 0.002002
|
Q06136,P38435,Q13315,P06280,P21964,P00403,P04062,O75844,O75306,P53701,P16278,Q9Y487,Q9NWM8,Q15427,P22830,Q14108,P03886,Q9UL01,Q99519,Q96L58,Q13535,Q16625,Q14739,Q8IZA0,P10619,P48651,P51648,P01889,Q13126,O60568
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
258,136,400,275,280,28,30,32,413,167,43,175,179,312,438,60,73,79,340,339,338,346,222,93,226,360,110,369,113,376
|
2173,1472,1438,454,2283,376,605,1776,2594,413,3248,32,1777,2743,1414,3045,28,369,1534,73,30,895,275,2526,2431,226,1189,2856,3340,1743,43,1444,2109,3303,896,1415,3127,2073,693,280,3163,438,3064,897,2800,3066,1813,1190,1911,2149,3281,136,2748,2111,1710,360,677,796,2361,110,524,619,167,2670,2326,821,1290,2934,1296,2511,2556,258,788,1578,1297,1857,113,400,3071,338,60,2113,222,2389,1821,312,1169,346,2652,680,822,2841,953,2051,580,2193,1019,698,93,2959,1523,2422,1378,3392,1134,339,1657,2312,340,2887,1046,1242,1942,1048,179,2472,632,2737,79,1069,2066,2917,2025,175,2815
|
-0.31905629408571334,0.02805701137235168,0.04479749007284595,0.9741576934609325,-0.373271876429598,1.1657819605638418,0.7169539114401163,-0.12517084870498654,-0.596278947334594,1.07084676596474,-1.3560056220962575,3.050846065270086,-0.12517084870498654,-0.7116898323792509,0.06148252180205109,-0.992089953515064,3.0698107589013315,1.179204988513675,-0.005591913085313469,2.4178172840822203,3.0603364192521147,0.41529180787632924,1.4151493408700357,-0.5395748804972572,-0.4649705794159142,1.6040461907838122,0.19301386899346543,-0.8099892376198776,-1.725900749051077,-0.10791253841717666,2.9065277890482055,0.04479749007284595,-0.2832385860448953,-1.5373416114687155,0.41529180787632924,0.06148252180205109,-1.096295452188383,-0.26542599868242417,0.6282990804246098,1.402314093228658,-1.1599171531024435,1.0158151806848401,-1.0127520150653435,0.41529180787632924,-0.7507725016906376,-1.0127520150653435,-0.1424888753229872,0.19301386899346543,-0.1948058268211105,-0.30111518243997987,-1.468526945815869,1.9975331678372859,-0.7116898323792509,-0.2832385860448953,-0.0907134950668146,1.2059486289837344,0.6431811538013191,0.5076661391022604,-0.40974773902190176,2.1784605959005607,0.861414936766202,0.7022834886797121,1.8459424393187207,-0.6536448751928122,-0.3914762369552328,0.47705956297724367,0.14408985151272588,-0.8699343008139493,0.14408985151272588,-0.5208177336190014,-0.558403728184664,1.4661818634308703,0.522901157152449,-0.02250118346835699,0.14408985151272588,-0.15986707294579158,2.167327425815136,1.1117439633053623,-1.0127520150653435,1.2590315225380515,2.5336885717746562,-0.2832385860448953,1.6164042064007391,-0.4280869276823581,-0.1424888753229872,1.3246420617522143,0.20921739577808898,1.2458108826688405,-0.6344483133432426,0.6431811538013191,0.47705956297724367,-0.7901703605422196,0.36847097049977656,-0.24767692023999524,0.7607169539788241,-0.31905629408571334,0.32121625895525563,0.6282990804246098,2.2667166943530197,-0.8900812583352817,0.01126068031324202,-0.4464943548499513,0.09468784334280253,-2.180159048860371,0.24146991514915547,1.2590315225380515,-0.0564914375226667,-0.373271876429598,1.2590315225380515,-0.8298890333091614,0.30536674022651894,0.17675834803240076,-0.1948058268211105,0.30536674022651894,1.798428045397234,-0.4835161673691688,0.7022834886797121,-0.6922649775615227,2.3750691920218543,0.2894676887918951,-0.24767692023999524,-0.8498704751461239,-0.22999085661134913,1.8103460646896083,-0.7507725016906376
| 3,430
|
Ventricular arrhythmia
| 14
| 43
| 3.089601
| 0.002004
|
O75306,P23786,P42892,O43772,Q9HD47,P36551,P03886,Q99959,P13473,P50402,Q14BN4,P10253,P00403,P12235
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
413,33,69,468,106,647,73,586,237,431,624,311,28,213
|
468,1874,413,2179,28,1534,73,858,1220,2597,1117,2965,311,213,237,1538,1743,2619,693,33,3167,647,2990,69,775,1258,1163,431,1891,2703,1670,1451,624,1863,2197,1043,1459,1624,937,586,1590,1087,106
|
0.9462000577616902,-0.1773059016141884,1.07084676596474,-0.31905629408571334,3.0698107589013315,-0.005591913085313469,2.4178172840822203,0.44626893355334946,0.17675834803240076,-0.596278947334594,0.24146991514915547,-0.9103121062691136,1.3246420617522143,1.641034754600386,1.554325783520826,-0.005591913085313469,-0.10791253841717666,-0.6153265492951593,0.6282990804246098,3.0318170762153325,-1.1599171531024435,0.6728169776242082,-0.9306276139125141,2.4496613605694386,0.5380910558331444,0.1604504658814682,0.20921739577808898,1.0296274822176772,-0.1773059016141884,-0.6729168790091554,-0.07357327446040215,0.04479749007284595,0.7022834886797121,-0.15986707294579158,-0.31905629408571334,0.30536674022651894,0.04479749007284595,-0.03946755021715677,0.3841256925736641,0.7461703883999292,-0.02250118346835699,0.2735187641595761,2.189571052524327
| 3,430
|
Heterogeneous
| 12
| 47
| 3.077998
| 0.002084
|
Q9BQE5,O75844,Q8TB36,P61916,P03886,Q9NR77,Q9Y619,P05067,Q13315,P01889,P12235,P21964
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
0,32,390,512,73,123,45,205,400,369,213,280
|
2318,1874,1637,32,3151,673,369,1534,73,1877,2225,205,2819,1254,1509,213,1743,280,1190,1781,2078,948,1541,1192,2509,524,2462,512,2046,400,2234,1451,1485,1374,1169,625,2867,390,2729,3404,2167,0,1006,123,1245,1531,45
|
-0.3914762369552328,-0.1773059016141884,-0.0564914375226667,3.050846065270086,-1.1386163266404463,0.6431811538013191,1.179204988513675,-0.005591913085313469,2.4178172840822203,-0.1773059016141884,-0.33706243340680064,1.6777690135569574,-0.7704316844994457,0.1604504658814682,0.01126068031324202,1.641034754600386,-0.10791253841717666,1.402314093228658,0.19301386899346543,-0.12517084870498654,-0.26542599868242417,0.36847097049977656,-0.005591913085313469,0.19301386899346543,-0.5208177336190014,0.861414936766202,-0.4835161673691688,0.8756421363992508,-0.24767692023999524,1.1117439633053623,-0.33706243340680064,0.04479749007284595,0.02805701137235168,0.09468784334280253,0.20921739577808898,0.7022834886797121,-0.8099892376198776,1.1388325289942267,-0.6922649775615227,-2.4814738005103227,-0.30111518243997987,3.937153403770652,0.33701658189477507,2.077431989617715,0.17675834803240076,0.01126068031324202,2.7982738550861823
| 3,430
|
Abnormal activity of mitochondrial respiratory chain
| 20
| 54
| 3.077017
| 0.002091
|
P51970,Q5JPH6,Q96CU9,Q9UBX3,Q7KZN9,Q70HW3,Q9Y2R0,O43676,Q9P0J0,O75306,Q86Y39,P21912,Q9Y6M9,O75648,Q9NPL8,P82663,P03886,P13073,O96000,Q9Y584
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
386,651,274,13,525,16,19,21,158,413,168,693,326,444,325,695,73,336,606,119
|
892,1950,21,2922,1441,413,978,1442,444,2033,606,73,2035,336,2639,1119,693,3031,3011,1747,1395,2507,3152,386,2669,2483,695,2995,1673,968,651,2092,16,525,168,1493,935,1459,274,1044,1865,2518,1408,816,1089,325,749,158,3124,13,19,2616,119,326
|
0.41529180787632924,-0.2123673195994045,3.200802504118346,-0.8699343008139493,0.04479749007284595,1.07084676596474,0.33701658189477507,0.04479749007284595,1.001966258000303,-0.24767692023999524,0.7169539114401163,2.4178172840822203,-0.24767692023999524,1.2590315225380515,-0.6344483133432426,0.24146991514915547,0.6282990804246098,-0.971515740451046,-0.9510285615071858,-0.10791253841717666,0.07811250742307049,-0.5208177336190014,-1.1386163266404463,1.1388325289942267,-0.6536448751928122,-0.5021316919187672,0.6282990804246098,-0.9306276139125141,-0.07357327446040215,0.3527680424371989,0.6728169776242082,-0.26542599868242417,3.2651743542921823,0.861414936766202,1.8459424393187207,0.02805701137235168,0.3841256925736641,0.04479749007284595,1.4279535786684734,0.30536674022651894,-0.15986707294579158,-0.5208177336190014,0.07811250742307049,0.4923857069491886,0.2735187641595761,1.2853737321434007,0.5833929390939195,1.8813049364421908,-1.075273613042021,3.391761695054266,3.2192694624153164,-0.596278947334594,2.1113172784145564,1.2853737321434007
| 3,430
|
Liposaccharide metabolic process
| 8
| 18
| 3.065175
| 0.002175
|
O43292,P17900,P16278,P06865,O60512,P06280,P04062,Q8NBX0
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
194,66,43,268,18,275,30,95
|
194,18,605,30,895,275,268,1358,43,66,2511,988,95,1083,1378,2761,340,640
|
1.738437938975464,3.237676205824806,0.7169539114401163,3.0603364192521147,0.41529180787632924,1.4151493408700357,1.4279535786684734,0.09468784334280253,2.9065277890482055,2.4918352621956807,-0.5208177336190014,0.33701658189477507,2.244786155021276,0.2735187641595761,0.09468784334280253,-0.7116898323792509,1.2590315225380515,0.6875712647067221
| 3,430
|
Alcohol metabolic process
| 25
| 87
| 3.059786
| 0.002215
|
Q9BQE5,O75874,P48735,P05091,Q06520,Q15392,Q14849,P04062,O15269,Q10713,P37268,Q8WTV0,P54646,P00374,P05067,Q16850,Q6NUM9,Q15800,Q14739,P16435,Q13510,P51648,O15118,Q14534,P35610
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
0,1,10,267,144,23,27,30,286,292,166,169,75,76,205,210,216,88,222,231,250,110,109,122,252
|
3416,109,286,295,3308,961,605,566,470,1,382,3338,2070,3389,76,1876,30,205,267,3301,3279,2697,2989,3141,231,1444,2799,1997,3376,928,2110,252,166,740,2776,556,753,10,1258,2991,1060,3310,2509,110,1855,3383,75,2081,3360,2266,512,2607,3426,3312,1450,144,292,250,3405,2234,3254,122,222,27,3220,23,1169,88,1720,210,3132,216,1457,1207,1175,169,2203,3387,3001,0,2492,1553,2065,632,2135,761,768
|
-3.3536129371984007,2.1784605959005607,1.3894476706931538,1.3636206339195902,-1.5605037593216007,0.3527680424371989,0.7169539114401163,0.7752227411673067,0.9462000577616902,3.92901774642917,1.1523245386286525,-1.725900749051077,-0.26542599868242417,-2.127435381597733,2.3964848636249685,-0.1773059016141884,3.0603364192521147,1.6777690135569574,1.4407269703301229,-1.5373416114687155,-1.468526945815869,-0.6729168790091554,-0.9306276139125141,-1.117409393747407,1.5792439505261,0.04479749007284595,-0.7507725016906376,-0.22999085661134913,-1.9981963448778324,0.3841256925736641,-0.2832385860448953,1.4915153034770001,1.8459424393187207,0.5833929390939195,-0.7311921139115007,0.7896879996375533,0.5683366593475094,3.454011813127605,0.1604504658814682,-0.9306276139125141,0.2894676887918951,-1.5605037593216007,-0.5208177336190014,2.1784605959005607,-0.15986707294579158,-2.0753063910430853,2.4071614359087854,-0.26542599868242417,-1.8477085071425041,-0.35513411913799386,0.8756421363992508,-0.596278947334594,-4.39045673764919,-1.5605037593216007,0.04479749007284595,1.9513415899455118,1.3765499068522848,1.5041368739934033,-2.5384586651582315,-0.33706243340680064,-1.3560056220962575,2.077431989617715,1.6164042064007391,3.0792691433168833,-1.267862233870033,3.1543688124281597,0.20921739577808898,2.310315469590055,-0.0907134950668146,1.6655522802639968,-1.096295452188383,1.641034754600386,0.04479749007284595,0.19301386899346543,0.20921739577808898,1.8459424393187207,-0.31905629408571334,-2.1012974711813244,-0.9306276139125141,3.937153403770652,-0.5021316919187672,-0.005591913085313469,-0.24767692023999524,0.7022834886797121,-0.2832385860448953,0.5683366593475094,0.5532361269354006
| 3,430
|
Abnormality of extrapyramidal motor function
| 18
| 75
| 3.054772
| 0.002252
|
P17900,P07602,P98175,P16278,Q06787,P05067,Q9NZJ7,P35637,P06865,Q6DKK2,O75569,Q9Y4P3,P12235,Q99720,O14949,P35610,P04062,Q15043
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
66,38,281,43,203,205,341,235,268,82,342,313,213,26,155,252,30,191
|
155,2350,870,1441,342,3248,3045,1443,2618,30,205,2819,268,38,1358,3225,676,1535,213,43,1996,66,896,1415,2324,2354,784,2775,2110,252,235,447,2509,1713,2387,1290,2266,2879,281,2529,741,3054,203,2609,2418,1485,3228,191,2299,651,822,82,2610,2393,972,3158,358,937,885,3387,26,1179,1136,688,2521,2376,341,1529,866,3097,1216,2025,313,3043,1025
|
1.8813049364421908,-0.40974773902190176,0.43080383738421585,0.04479749007284595,1.2458108826688405,-1.3560056220962575,-0.992089953515064,0.04479749007284595,-0.6153265492951593,3.0603364192521147,1.6777690135569574,-0.7704316844994457,1.4279535786684734,3.0127233121243298,0.09468784334280253,-1.289746149293953,0.6431811538013191,-0.005591913085313469,1.641034754600386,2.9065277890482055,-0.22999085661134913,2.4918352621956807,0.41529180787632924,0.06148252180205109,-0.3914762369552328,-0.40974773902190176,0.522901157152449,-0.7311921139115007,-0.2832385860448953,1.4915153034770001,1.5667994320520733,1.001966258000303,-0.5208177336190014,-0.0907134950668146,-0.4280869276823581,0.14408985151272588,-0.35513411913799386,-0.8298890333091614,1.402314093228658,-0.5395748804972572,0.5833929390939195,-0.992089953515064,1.7021191193583658,-0.596278947334594,-0.4464943548499513,0.02805701137235168,-1.289746149293953,1.750489731196436,-0.373271876429598,0.6728169776242082,0.47705956297724367,2.342788021416518,-0.596278947334594,-0.4280869276823581,0.3527680424371989,-1.1386163266404463,1.2192696206606266,0.3841256925736641,0.43080383738421585,-2.1012974711813244,3.107549151128594,0.20921739577808898,0.24146991514915547,0.6431811538013191,-0.5208177336190014,-0.40974773902190176,1.2590315225380515,0.01126068031324202,0.44626893355334946,-1.0335027512907717,0.19301386899346543,-0.22999085661134913,1.3246420617522143,-0.971515740451046,0.32121625895525563
| 3,430
|
RNA recognition motif domain [IPR000504]
| 44
| 124
| 3.040273
| 0.002364
|
Q14011,P78332,P14866,P52756,P11940,Q14103,Q01844,P98175,Q9BWF3,P98179,P51991,Q99729,Q13151,Q13595,Q01085,P07910,Q15427,Q9P2N5,Q96DH6,O60506,A0AV96,P52597,O43390,P55795,P62995,P31483,Q9UKA9,P23246,P43243,Q96EP5,P31943,P26368,Q9UKM9,P22626,P31942,P23588,Q92804,P38159,Q76FK4,P35637,Q96PK6,O14979,Q9UHX1,Q01081
|
Sequence
|
InterPro Domain
|
interpro_domain
|
636,650,772,395,394,149,282,281,411,419,297,170,426,301,558,675,312,183,700,187,690,318,195,196,576,322,460,584,585,720,200,710,733,343,217,724,223,351,481,235,493,108,118,755
|
690,1949,108,1070,1849,195,2692,187,1282,3125,1810,783,3249,675,3083,1286,1315,981,394,772,2746,2638,343,584,724,710,2527,322,217,200,2077,235,351,2551,585,1512,297,1012,1667,318,395,196,2415,576,650,1449,281,419,755,558,282,3244,1397,2822,2188,2418,426,1167,2047,2935,2880,1336,301,636,149,1617,1230,1125,1858,2299,1078,1168,878,312,1452,2049,3038,2652,1895,481,2274,2755,1680,1862,1492,1828,879,1341,2489,1522,999,2239,1042,223,1343,700,720,1500,493,1758,2312,170,3057,411,1157,1687,3333,2427,2209,2570,1245,2169,1308,183,118,460,733,1989,3079,1846,867,836,2281,1140
|
0.6282990804246098,-0.2123673195994045,2.1784605959005607,0.2735187641595761,-0.15986707294579158,1.738437938975464,-0.6729168790091554,1.7625145060761207,0.14408985151272588,-1.096295452188383,-0.1424888753229872,0.522901157152449,-1.3560056220962575,0.6431811538013191,-1.0335027512907717,0.14408985151272588,0.1276761298241045,0.33701658189477507,1.125305736257329,0.5380910558331444,-0.7116898323792509,-0.6344483133432426,1.2458108826688405,0.7461703883999292,0.5984052493734849,0.6133738705970863,-0.5395748804972572,1.2853737321434007,1.6287336796515217,1.7263589960332117,-0.26542599868242417,1.5667994320520733,1.2325569767034361,-0.558403728184664,0.7461703883999292,0.01126068031324202,1.3636206339195902,0.32121625895525563,-0.07357327446040215,1.2984956621256847,1.125305736257329,1.738437938975464,-0.4464943548499513,0.7607169539788241,0.6728169776242082,0.04479749007284595,1.402314093228658,1.057143066123191,0.5683366593475094,0.7896879996375533,1.402314093228658,-1.333816816277065,0.07811250742307049,-0.7704316844994457,-0.31905629408571334,-0.4464943548499513,1.04340337414266,0.20921739577808898,-0.24767692023999524,-0.8699343008139493,-0.8298890333091614,0.11120892157867891,1.3506596827179598,0.6875712647067221,1.904751655596212,-0.03946755021715677,0.17675834803240076,0.24146991514915547,-0.15986707294579158,-0.373271876429598,0.2735187641595761,0.20921739577808898,0.43080383738421585,1.3246420617522143,0.04479749007284595,-0.24767692023999524,-0.971515740451046,-0.6344483133432426,-0.1773059016141884,0.9321647887240839,-0.35513411913799386,-0.7116898323792509,-0.07357327446040215,-0.15986707294579158,0.02805701137235168,-0.1424888753229872,0.43080383738421585,0.11120892157867891,-0.5021316919187672,0.01126068031324202,0.33701658189477507,-0.33706243340680064,0.30536674022651894,1.6164042064007391,0.11120892157867891,0.6282990804246098,0.6133738705970863,0.02805701137235168,0.9180915884762,-0.10791253841717666,-0.373271876429598,1.8459424393187207,-0.992089953515064,1.0845146796370766,0.22536929144369766,-0.07357327446040215,-1.6780491319681583,-0.4464943548499513,-0.31905629408571334,-0.558403728184664,0.17675834803240076,-0.30111518243997987,0.14408985151272588,1.7864835322979642,2.1113172784145564,0.9741576934609325,0.5984052493734849,-0.2123673195994045,-1.0127520150653435,-0.1424888753229872,0.44626893355334946,0.47705956297724367,-0.35513411913799386,0.24146991514915547
| 3,430
|
Localized skin lesion
| 54
| 230
| 3.036887
| 0.00239
|
Q7LGA3,Q06136,O75874,P61978,P38435,P48735,O15460,P16615,Q13315,P06280,O95202,Q6DKJ4,Q15392,P21964,P04062,O75844,O15269,Q15022,O43683,P07602,P53701,O15270,Q9Y619,Q9NWM8,Q15427,Q9Y4P3,Q9NZ08,P42858,O75648,Q06787,O15360,P61586,Q9NZJ7,Q9UL01,Q96L58,Q96PU5,O96028,Q03519,Q03518,Q8IZA0,Q14739,P42345,Q8TAA9,Q96AY3,P48651,Q6ZXV5,Q6PGP7,P35637,P01889,Q13126,Q96PZ0,Q96MF7,Q9UHX1,Q13510
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
128,258,1,387,136,10,398,269,400,275,401,406,23,280,30,32,286,542,539,38,167,295,45,179,312,313,185,447,444,203,454,337,341,79,339,211,334,215,218,93,222,353,482,357,360,233,480,235,369,113,498,507,118,250
|
2173,1472,3401,1438,1738,2407,286,295,454,398,926,1328,3060,1439,539,2987,2350,961,837,1874,1097,1009,1473,1776,2409,3007,3300,2574,1010,1638,444,2818,32,1,1533,1777,401,2743,1414,927,2595,334,1951,369,1534,858,30,1877,2949,275,2526,38,1954,1145,1189,1535,3340,1743,269,2109,3303,896,1880,1415,3191,3127,2073,693,280,2859,3163,2457,1850,738,897,2800,1813,928,1190,2775,235,3068,2413,647,2078,136,3050,2111,1710,353,447,1884,2001,2749,2778,360,10,796,2991,1163,805,1120,2953,167,2670,2326,2623,821,574,1290,2292,2862,337,387,2043,2992,2555,2879,1513,609,1198,1450,1891,2934,1296,2703,807,218,215,741,2364,2511,2556,258,203,1578,1297,2045,550,1921,113,400,2626,2973,250,2235,1322,1671,222,542,2825,2299,3220,1821,1078,2237,23,312,2439,1374,2366,2676,2725,406,580,744,2867,480,233,128,1795,1796,3313,93,2010,2276,3355,2395,482,2872,1497,2057,612,1131,2729,2422,2241,1834,357,339,507,211,498,2761,1380,2312,885,2124,1046,1242,1048,2685,1138,2370,1763,1307,3371,1903,2022,2209,179,2472,2376,185,341,1092,3397,118,866,79,2875,668,2139,2066,2572,1470,1633,313,2281,45
|
-0.31905629408571334,0.02805701137235168,-2.397311077076706,0.04479749007284595,-0.10791253841717666,-0.4464943548499513,1.3894476706931538,1.3636206339195902,0.9741576934609325,1.1117439633053623,0.3841256925736641,0.11120892157867891,-1.0127520150653435,0.04479749007284595,0.8184979173823138,-0.9306276139125141,-0.40974773902190176,0.3527680424371989,0.4616874064468927,-0.1773059016141884,0.25751962221115077,0.32121625895525563,0.02805701137235168,-0.12517084870498654,-0.4464943548499513,-0.9510285615071858,-1.5373416114687155,-0.5773048800496771,0.32121625895525563,-0.0564914375226667,1.001966258000303,-0.7704316844994457,3.050846065270086,3.92901774642917,-0.005591913085313469,-0.12517084870498654,1.0981470112960925,-0.7116898323792509,0.06148252180205109,0.3841256925736641,-0.596278947334594,1.2590315225380515,-0.2123673195994045,1.179204988513675,-0.005591913085313469,0.44626893355334946,3.0603364192521147,-0.1773059016141884,-0.8900812583352817,1.4151493408700357,-0.5395748804972572,3.0127233121243298,-0.2123673195994045,0.22536929144369766,0.19301386899346543,-0.005591913085313469,-1.725900749051077,-0.10791253841717666,1.4279535786684734,-0.2832385860448953,-1.5373416114687155,0.41529180787632924,-0.1773059016141884,0.06148252180205109,-1.2028041638743916,-1.096295452188383,-0.26542599868242417,0.6282990804246098,1.402314093228658,-0.8099892376198776,-1.1599171531024435,-0.4835161673691688,-0.15986707294579158,0.5833929390939195,0.41529180787632924,-0.7507725016906376,-0.1424888753229872,0.3841256925736641,0.19301386899346543,-0.7311921139115007,1.5667994320520733,-1.0127520150653435,-0.4464943548499513,0.6728169776242082,-0.26542599868242417,1.9975331678372859,-0.992089953515064,-0.2832385860448953,-0.0907134950668146,1.2192696206606266,1.001966258000303,-0.1773059016141884,-0.22999085661134913,-0.7116898323792509,-0.7311921139115007,1.2059486289837344,3.454011813127605,0.5076661391022604,-0.9306276139125141,0.20921739577808898,0.4923857069491886,0.24146991514915547,-0.8900812583352817,1.8459424393187207,-0.6536448751928122,-0.3914762369552328,-0.6153265492951593,0.47705956297724367,0.7607169539788241,0.14408985151272588,-0.373271876429598,-0.8099892376198776,1.2590315225380515,1.1388325289942267,-0.24767692023999524,-0.9306276139125141,-0.558403728184664,-0.8298890333091614,0.01126068031324202,0.7169539114401163,0.19301386899346543,0.04479749007284595,-0.1773059016141884,-0.8699343008139493,0.14408985151272588,-0.6729168790091554,0.4923857069491886,1.6287336796515217,1.641034754600386,0.5833929390939195,-0.40974773902190176,-0.5208177336190014,-0.558403728184664,1.4661818634308703,1.7021191193583658,-0.02250118346835699,0.14408985151272588,-0.24767692023999524,0.8041129767098191,-0.1948058268211105,2.167327425815136,1.1117439633053623,-0.6153265492951593,-0.9103121062691136,1.5041368739934033,-0.33706243340680064,0.1276761298241045,-0.07357327446040215,1.6164042064007391,0.8184979173823138,-0.7704316844994457,-0.373271876429598,-1.267862233870033,-0.1424888753229872,0.2735187641595761,-0.33706243340680064,3.1543688124281597,1.3246420617522143,-0.4649705794159142,0.09468784334280253,-0.40974773902190176,-0.6536448751928122,-0.6922649775615227,1.0845146796370766,0.7607169539788241,0.5833929390939195,-0.8099892376198776,0.9321647887240839,1.5792439505261,2.0547236877093185,-0.12517084870498654,-0.12517084870498654,-1.5605037593216007,2.2667166943530197,-0.22999085661134913,-0.35513411913799386,-1.8230922651443087,-0.4280869276823581,0.9321647887240839,-0.8099892376198776,0.02805701137235168,-0.24767692023999524,0.7169539114401163,0.24146991514915547,-0.6922649775615227,-0.4464943548499513,-0.33706243340680064,-0.1424888753229872,1.2192696206606266,1.2590315225380515,0.8898304908049921,1.6655522802639968,0.903980231650309,-0.7116898323792509,0.09468784334280253,-0.373271876429598,0.43080383738421585,-0.2832385860448953,0.30536674022651894,0.17675834803240076,0.30536674022651894,-0.6536448751928122,0.24146991514915547,-0.40974773902190176,-0.10791253841717666,0.14408985151272588,-1.9474917631058593,-0.1773059016141884,-0.22999085661134913,-0.31905629408571334,1.798428045397234,-0.4835161673691688,-0.40974773902190176,1.774512395985724,1.2590315225380515,0.2735187641595761,-2.2874512966961964,2.1113172784145564,0.44626893355334946,2.3750691920218543,-0.8099892376198776,0.65802036299361,-0.2832385860448953,-0.24767692023999524,-0.558403728184664,0.04479749007284595,-0.03946755021715677,1.3246420617522143,-0.35513411913799386,2.7982738550861823
| 3,430
|
Increased susceptibility to fractures
| 14
| 59
| 3.035597
| 0.002401
|
O75874,Q32P28,O15269,Q96AY3,P16435,P48735,O15270,Q96L58,Q13126,P22626,O75718,Q14108,Q14739,P04062
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
1,34,286,357,231,10,295,339,113,343,89,60,222,30
|
2107,286,295,376,1776,89,470,1,2897,2179,1414,3151,30,1877,3232,2526,2819,1284,981,1189,231,2109,3303,343,3163,3328,1813,1190,2111,1710,10,524,2821,2387,1450,2364,1968,2045,113,1646,60,2114,222,34,2725,1497,357,339,1463,1046,3172,2735,2370,2472,1092,761,2139,2170,1470
|
-0.2832385860448953,1.3894476706931538,1.3636206339195902,1.1657819605638418,-0.12517084870498654,2.2994483251380298,0.9462000577616902,3.92901774642917,-0.8498704751461239,-0.31905629408571334,0.06148252180205109,-1.1386163266404463,3.0603364192521147,-0.1773059016141884,-1.3117306703903504,-0.5395748804972572,-0.7704316844994457,0.14408985151272588,0.33701658189477507,0.19301386899346543,1.5792439505261,-0.2832385860448953,-1.5373416114687155,1.2458108826688405,-1.1599171531024435,-1.6543045466896755,-0.1424888753229872,0.19301386899346543,-0.2832385860448953,-0.0907134950668146,3.454011813127605,0.861414936766202,-0.7704316844994457,-0.4280869276823581,0.04479749007284595,-0.40974773902190176,-0.2123673195994045,-0.24767692023999524,2.167327425815136,-0.0564914375226667,2.5336885717746562,-0.2832385860448953,1.6164042064007391,3.0318170762153325,-0.6922649775615227,0.02805701137235168,1.2192696206606266,1.2590315225380515,0.04479749007284595,0.30536674022651894,-1.1599171531024435,-0.6922649775615227,-0.40974773902190176,-0.4835161673691688,0.2735187641595761,0.5683366593475094,-0.2832385860448953,-0.30111518243997987,0.04479749007284595
| 3,430
|
Regulation of hormone levels
| 14
| 68
| 3.031404
| 0.002434
|
O75844,P30536,Q53GQ0,P42892,Q9HB40,P16435,Q06520,P53985,Q15907,P04083,Q6NUM9,O95470,Q14849,Q15043
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
32,2,262,69,40,231,144,271,276,148,216,86,27,191
|
857,1948,2796,1774,1354,1161,2256,32,3338,1639,86,839,673,858,148,607,2548,2148,3141,231,2637,316,2,3166,948,740,69,3169,1058,1194,1011,271,3182,2081,2004,1918,2556,144,2993,1337,27,191,2190,276,1720,625,262,216,2335,2054,996,1493,515,1207,1623,1130,1175,1499,1380,2205,3387,1837,40,1092,632,3097,1632,768
|
0.44626893355334946,-0.2123673195994045,-0.7507725016906376,-0.12517084870498654,0.09468784334280253,0.20921739577808898,-0.35513411913799386,3.050846065270086,-1.725900749051077,-0.0564914375226667,2.321161071650228,0.4616874064468927,0.6431811538013191,0.44626893355334946,1.904751655596212,0.7169539114401163,-0.558403728184664,-0.30111518243997987,-1.117409393747407,1.5792439505261,-0.6344483133432426,1.2984956621256847,3.92901774642917,-1.1599171531024435,0.36847097049977656,0.5833929390939195,2.4496613605694386,-1.1599171531024435,0.2894676887918951,0.19301386899346543,0.32121625895525563,1.4279535786684734,-1.1813127889529935,-0.26542599868242417,-0.22999085661134913,-0.1948058268211105,-0.558403728184664,1.9513415899455118,-0.9306276139125141,0.11120892157867891,3.0792691433168833,1.750489731196436,-0.31905629408571334,1.4151493408700357,-0.0907134950668146,0.7022834886797121,1.4534696782308594,1.641034754600386,-0.3914762369552328,-0.24767692023999524,0.33701658189477507,0.02805701137235168,0.8756421363992508,0.19301386899346543,-0.03946755021715677,0.24146991514915547,0.20921739577808898,0.02805701137235168,0.09468784334280253,-0.31905629408571334,-2.1012974711813244,-0.1424888753229872,2.983960149974089,0.2735187641595761,0.7022834886797121,-1.0335027512907717,-0.03946755021715677,0.5532361269354006
| 3,430
|
Variable expressivity
| 14
| 80
| 3.028638
| 0.002457
|
P17900,P07602,Q6P4A7,P03886,Q9H061,P00374,O76031,Q70HW3,O95470,Q9NWS8,Q15427,Q13510,Q9NR77,P00403
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
66,38,232,73,12,76,251,16,86,182,312,250,123,28
|
892,1948,1559,3418,781,605,3149,251,1414,86,76,28,1534,73,445,2819,1254,38,2548,1568,676,66,1960,2110,2748,3051,1884,585,775,2967,1886,2361,1120,1713,2387,3114,1195,2529,1783,2608,1968,2045,3296,250,949,1616,623,1202,312,951,810,2092,822,232,1104,16,920,935,639,2729,1459,1241,904,1005,940,12,1660,850,2983,123,182,341,1051,955,1216,1350,1280,2025,1025,1698
|
0.41529180787632924,-0.2123673195994045,-0.02250118346835699,-3.637988436906538,0.522901157152449,0.7169539114401163,-1.1386163266404463,1.4915153034770001,0.06148252180205109,2.321161071650228,2.3964848636249685,3.0698107589013315,-0.005591913085313469,2.4178172840822203,1.001966258000303,-0.7704316844994457,0.1604504658814682,3.0127233121243298,-0.558403728184664,-0.02250118346835699,0.6431811538013191,2.4918352621956807,-0.2123673195994045,-0.2832385860448953,-0.7116898323792509,-0.992089953515064,-0.1773059016141884,0.7461703883999292,0.5380910558331444,-0.9103121062691136,-0.1773059016141884,-0.40974773902190176,0.24146991514915547,-0.0907134950668146,-0.4280869276823581,-1.075273613042021,0.19301386899346543,-0.5395748804972572,-0.12517084870498654,-0.596278947334594,-0.2123673195994045,-0.24767692023999524,-1.5142922206614813,1.5041368739934033,0.36847097049977656,-0.03946755021715677,0.7022834886797121,0.19301386899346543,1.3246420617522143,0.36847097049977656,0.4923857069491886,-0.26542599868242417,0.47705956297724367,1.5792439505261,0.25751962221115077,3.2651743542921823,0.3997325317718629,0.3841256925736641,0.6875712647067221,-0.6922649775615227,0.04479749007284595,0.17675834803240076,0.41529180787632924,0.33701658189477507,0.3841256925736641,3.4362955117330025,-0.0564914375226667,0.4616874064468927,-0.9103121062691136,2.077431989617715,1.7864835322979642,1.2590315225380515,0.30536674022651894,0.36847097049977656,0.19301386899346543,0.11120892157867891,0.1604504658814682,-0.22999085661134913,0.32121625895525563,-0.07357327446040215
| 3,430
|
Abnormality of femur morphology
| 21
| 74
| 3.027216
| 0.002468
|
Q7LGA3,P06280,P04062,O95831,O75844,Q32P28,P07602,P16278,Q9Y619,Q9Y487,Q6NUQ1,Q9NZJ7,Q96L58,O75718,Q14739,Q96AY3,P16435,Q9UHX1,Q96HY6,Q96A33,O60568
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
128,275,30,414,32,34,38,43,45,175,452,341,339,89,222,357,231,118,380,379,376
|
1184,1389,2107,977,1438,454,837,376,2574,1010,89,32,2223,927,414,3151,1534,30,895,1877,275,3232,38,1256,43,231,3127,2262,2800,3049,2078,3050,3402,2290,2079,524,619,2483,574,2862,222,2091,1486,34,452,2845,128,2677,2959,1079,2872,2729,379,357,2308,380,339,1657,779,2123,1242,2735,3371,2963,2022,341,1092,118,2875,2170,2917,175,2281,45
|
0.19301386899346543,0.07811250742307049,-0.2832385860448953,0.33701658189477507,0.04479749007284595,0.9741576934609325,0.4616874064468927,1.1657819605638418,-0.5773048800496771,0.32121625895525563,2.2994483251380298,3.050846065270086,-0.33706243340680064,0.3841256925736641,1.07084676596474,-1.1386163266404463,-0.005591913085313469,3.0603364192521147,0.41529180787632924,-0.1773059016141884,1.4151493408700357,-1.3117306703903504,3.0127233121243298,0.1604504658814682,2.9065277890482055,1.5792439505261,-1.096295452188383,-0.35513411913799386,-0.7507725016906376,-0.992089953515064,-0.26542599868242417,-0.992089953515064,-2.425193190684344,-0.373271876429598,-0.26542599868242417,0.861414936766202,0.7022834886797121,-0.5021316919187672,0.7607169539788241,-0.8099892376198776,1.6164042064007391,-0.26542599868242417,0.02805701137235168,3.0318170762153325,0.98808050071691,-0.7901703605422196,2.0547236877093185,-0.6536448751928122,-0.8900812583352817,0.2735187641595761,-0.8099892376198776,-0.6922649775615227,1.1657819605638418,1.2192696206606266,-0.373271876429598,1.1657819605638418,1.2590315225380515,-0.0564914375226667,0.5380910558331444,-0.2832385860448953,0.17675834803240076,-0.6922649775615227,-1.9474917631058593,-0.8900812583352817,-0.22999085661134913,1.2590315225380515,0.2735187641595761,2.1113172784145564,-0.8099892376198776,-0.30111518243997987,-0.8498704751461239,1.8103460646896083,-0.35513411913799386,2.7982738550861823
| 3,430
|
Tclin
| 31
| 87
| 3.025007
| 0.002486
|
P51970,P38435,P48735,P05091,Q07864,P49721,O95168,P06280,Q9UBN7,O43676,Q99720,P21964,Q9P0J0,O75306,Q86Y39,O75438,P20618,P10253,P07437,P04350,Q9Y6M9,P55011,P03886,P00374,P31350,P42345,Q9P032,P05023,O96000,Q9Y2I1,Q13885
|
Drugs and Diseases
|
Pharos IDG Category
|
pharos_protein_category
|
386,136,10,267,788,142,529,275,666,21,26,280,158,413,168,671,437,311,310,445,326,574,73,76,711,353,749,607,606,633,623
|
892,1950,21,2922,2379,1441,413,978,671,1442,529,3008,2033,606,76,980,3027,73,858,445,1811,607,267,1607,275,310,2034,2036,2431,2965,311,3009,1256,1741,1779,1535,2666,2697,3141,2639,437,280,2698,1287,3181,1851,1881,3031,897,711,2413,136,353,10,142,3152,2040,1963,386,1574,574,787,1918,2934,2511,863,788,1483,1123,623,3131,1673,2784,168,1493,2536,26,1552,2518,1241,1005,749,158,666,1736,633,326
|
0.41529180787632924,-0.2123673195994045,3.200802504118346,-0.8699343008139493,-0.4280869276823581,0.04479749007284595,1.07084676596474,0.33701658189477507,0.6431811538013191,0.04479749007284595,0.8471486580863727,-0.9510285615071858,-0.24767692023999524,0.7169539114401163,2.3964848636249685,0.33701658189477507,-0.971515740451046,2.4178172840822203,0.44626893355334946,1.001966258000303,-0.1424888753229872,0.7169539114401163,1.4407269703301229,-0.03946755021715677,1.4151493408700357,1.3246420617522143,-0.24767692023999524,-0.24767692023999524,-0.4649705794159142,-0.9103121062691136,1.3246420617522143,-0.9510285615071858,0.1604504658814682,-0.10791253841717666,-0.12517084870498654,-0.005591913085313469,-0.6536448751928122,-0.6729168790091554,-1.117409393747407,-0.6344483133432426,1.0158151806848401,1.402314093228658,-0.6729168790091554,0.14408985151272588,-1.1813127889529935,-0.15986707294579158,-0.1773059016141884,-0.971515740451046,0.41529180787632924,0.6133738705970863,-0.4464943548499513,1.9975331678372859,1.2192696206606266,3.454011813127605,1.9629265380559953,-1.1386163266404463,-0.24767692023999524,-0.2123673195994045,1.1388325289942267,-0.02250118346835699,0.7607169539788241,0.522901157152449,-0.1948058268211105,-0.8699343008139493,-0.5208177336190014,0.44626893355334946,0.522901157152449,0.02805701137235168,0.24146991514915547,0.7022834886797121,-1.096295452188383,-0.07357327446040215,-0.7311921139115007,1.8459424393187207,0.02805701137235168,-0.5395748804972572,3.107549151128594,-0.005591913085313469,-0.5208177336190014,0.17675834803240076,0.33701658189477507,0.5833929390939195,1.8813049364421908,0.65802036299361,-0.0907134950668146,0.7022834886797121,1.2853737321434007
| 3,430
|
Decreased activity of mitochondrial complex i
| 11
| 36
| 3.022317
| 0.002508
|
O75306,P51970,Q9Y6M9,Q9NPL8,Q86Y39,P03886,Q96CU9,Q9UBX3,Q70HW3,O43676,Q9Y584
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
413,386,326,325,168,73,274,13,16,21,119
|
892,21,1441,413,978,1442,444,606,73,2639,3031,2507,3152,386,2669,2483,651,2092,16,168,1493,935,1459,274,1044,1865,2518,1408,816,1089,325,749,13,2616,119,326
|
0.41529180787632924,3.200802504118346,0.04479749007284595,1.07084676596474,0.33701658189477507,0.04479749007284595,1.001966258000303,0.7169539114401163,2.4178172840822203,-0.6344483133432426,-0.971515740451046,-0.5208177336190014,-1.1386163266404463,1.1388325289942267,-0.6536448751928122,-0.5021316919187672,0.6728169776242082,-0.26542599868242417,3.2651743542921823,1.8459424393187207,0.02805701137235168,0.3841256925736641,0.04479749007284595,1.4279535786684734,0.30536674022651894,-0.15986707294579158,-0.5208177336190014,0.07811250742307049,0.4923857069491886,0.2735187641595761,1.2853737321434007,0.5833929390939195,3.391761695054266,-0.596278947334594,2.1113172784145564,1.2853737321434007
| 3,430
|
Pain
| 36
| 183
| 3.018186
| 0.002543
|
O75874,P48735,Q15165,Q70HW3,Q13423,P06280,Q01844,P21964,P04062,O75844,P23786,O15269,P07602,O15270,Q9Y4P3,Q9NZ08,Q14108,Q15043,P42892,Q06787,Q9NZJ7,Q9UL01,O75569,P22626,P12235,Q15800,Q14566,Q14739,Q92804,P35637,P14854,P01889,Q96HY6,Q13510,Q9NR77,O60313
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
1,10,139,16,146,275,282,280,30,32,33,286,38,295,313,185,60,191,69,203,341,79,342,343,213,88,345,222,223,235,363,369,380,250,123,375
|
2173,1472,1559,1438,604,286,295,398,781,2350,375,1874,566,1187,342,32,1,1993,3151,1951,3330,369,1534,30,3319,1877,275,3232,2526,38,1358,2596,3365,3189,2597,981,1189,2411,3358,3301,213,1223,1536,363,1444,896,2619,1415,1446,2073,693,280,1665,2859,343,3163,33,3064,2287,2576,1747,3066,1190,2775,235,647,2357,2078,2111,1710,2801,948,69,585,2001,10,796,1258,1163,431,1192,912,1612,524,2264,805,1712,986,2670,821,2387,2510,1195,2327,2862,2879,1198,282,696,1227,3194,2364,2511,2556,203,788,1578,1968,478,3296,1422,1857,2418,2824,146,250,1228,1670,60,1485,3275,345,1202,222,2389,2390,191,2299,139,2366,88,3185,3337,491,2906,2725,2976,2867,1019,16,1897,611,627,482,1833,663,2306,1043,747,223,2422,1176,1378,2873,2308,380,937,885,1087,1212,886,2735,816,850,1089,2914,123,1245,185,341,1214,750,2737,547,3174,866,79,761,2712,1247,1470,313,2214
|
-0.31905629408571334,0.02805701137235168,-0.02250118346835699,0.04479749007284595,0.7169539114401163,1.3894476706931538,1.3636206339195902,1.1117439633053623,0.522901157152449,-0.40974773902190176,1.1657819605638418,-0.1773059016141884,0.7752227411673067,0.19301386899346543,1.2458108826688405,3.050846065270086,3.92901774642917,-0.22999085661134913,-1.1386163266404463,-0.2123673195994045,-1.6780491319681583,1.179204988513675,-0.005591913085313469,3.0603364192521147,-1.6071712099891131,-0.1773059016141884,1.4151493408700357,-1.3117306703903504,-0.5395748804972572,3.0127233121243298,0.09468784334280253,-0.596278947334594,-1.8973333941997261,-1.2028041638743916,-0.596278947334594,0.33701658189477507,0.19301386899346543,-0.4464943548499513,-1.8477085071425041,-1.5373416114687155,1.641034754600386,0.17675834803240076,-0.005591913085313469,1.1925938145223307,0.04479749007284595,0.41529180787632924,-0.6153265492951593,0.06148252180205109,0.04479749007284595,-0.26542599868242417,0.6282990804246098,1.402314093228658,-0.07357327446040215,-0.8099892376198776,1.2458108826688405,-1.1599171531024435,3.0318170762153325,-1.0127520150653435,-0.373271876429598,-0.5773048800496771,-0.10791253841717666,-1.0127520150653435,0.19301386899346543,-0.7311921139115007,1.5667994320520733,0.6728169776242082,-0.40974773902190176,-0.26542599868242417,-0.2832385860448953,-0.0907134950668146,-0.7507725016906376,0.36847097049977656,2.4496613605694386,0.7461703883999292,-0.22999085661134913,3.454011813127605,0.5076661391022604,0.1604504658814682,0.20921739577808898,1.0296274822176772,0.19301386899346543,0.3997325317718629,-0.03946755021715677,0.861414936766202,-0.35513411913799386,0.4923857069491886,-0.0907134950668146,0.33701658189477507,-0.6536448751928122,0.47705956297724367,-0.4280869276823581,-0.5208177336190014,0.19301386899346543,-0.3914762369552328,-0.8099892376198776,-0.8298890333091614,0.19301386899346543,1.402314093228658,0.6282990804246098,0.17675834803240076,-1.2028041638743916,-0.40974773902190176,-0.5208177336190014,-0.558403728184664,1.7021191193583658,0.522901157152449,-0.02250118346835699,-0.2123673195994045,0.9321647887240839,-1.5142922206614813,0.06148252180205109,-0.15986707294579158,-0.4464943548499513,-0.7704316844994457,1.9280968875332776,1.5041368739934033,0.17675834803240076,-0.07357327446040215,2.5336885717746562,0.02805701137235168,-1.445808727840182,1.2458108826688405,0.19301386899346543,1.6164042064007391,-0.4280869276823581,-0.4280869276823581,1.750489731196436,-0.373271876429598,1.9744867066455778,-0.40974773902190176,2.310315469590055,-1.1813127889529935,-1.701914084340314,0.9180915884762,-0.8498704751461239,-0.6922649775615227,-0.9103121062691136,-0.8099892376198776,0.32121625895525563,3.2651743542921823,-0.1773059016141884,0.7169539114401163,0.7022834886797121,0.9321647887240839,-0.1424888753229872,0.65802036299361,-0.373271876429598,0.30536674022651894,0.5833929390939195,1.6164042064007391,-0.4464943548499513,0.20921739577808898,0.09468784334280253,-0.8099892376198776,-0.373271876429598,1.1657819605638418,0.3841256925736641,0.43080383738421585,0.2735187641595761,0.19301386899346543,0.43080383738421585,-0.6922649775615227,0.4923857069491886,0.4616874064468927,0.2735187641595761,-0.8498704751461239,2.077431989617715,0.17675834803240076,1.774512395985724,1.2590315225380515,0.19301386899346543,0.5833929390939195,-0.6922649775615227,0.8184979173823138,-1.1599171531024435,0.44626893355334946,2.3750691920218543,0.5683366593475094,-0.6729168790091554,0.17675834803240076,0.04479749007284595,1.3246420617522143,-0.31905629408571334
| 3,430
|
Limb joint contracture
| 23
| 104
| 3.016106
| 0.00256
|
Q7LGA3,Q6DKJ4,Q15392,Q99720,Q86XL3,O75844,P23786,P49902,P37268,Q99567,Q9Y619,P42892,Q96L58,Q13535,Q8IZA0,Q96AY3,P16435,P48651,P35637,Q9NR77,O60313,O60568,Q14738
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
128,406,23,26,161,32,33,160,166,42,45,69,339,338,93,357,231,360,235,123,375,376,254
|
1948,1389,1437,2107,2816,1438,2174,3060,837,2217,375,376,605,2143,1356,566,32,2070,1777,3286,1534,2819,1254,1256,1538,1743,231,896,3127,693,2859,33,738,2800,1747,1813,235,2149,166,2111,3234,69,3402,360,160,431,2079,2509,821,3129,1195,1815,1450,1296,2608,1297,338,2235,1670,2113,254,2091,542,1488,1821,23,1676,406,2051,128,161,919,93,1494,2565,639,1833,1043,3346,2120,357,339,2312,42,26,2123,1087,2279,2540,1763,3424,850,123,2875,1349,2170,2896,1436,1847,2741,1698,3388,45,2172
|
-0.2123673195994045,0.07811250742307049,0.04479749007284595,-0.2832385860448953,-0.7704316844994457,0.04479749007284595,-0.31905629408571334,-1.0127520150653435,0.4616874064468927,-0.33706243340680064,1.1657819605638418,1.1657819605638418,0.7169539114401163,-0.30111518243997987,0.09468784334280253,0.7752227411673067,3.050846065270086,-0.26542599868242417,-0.12517084870498654,-1.4913543909405875,-0.005591913085313469,-0.7704316844994457,0.1604504658814682,0.1604504658814682,-0.005591913085313469,-0.10791253841717666,1.5792439505261,0.41529180787632924,-1.096295452188383,0.6282990804246098,-0.8099892376198776,3.0318170762153325,0.5833929390939195,-0.7507725016906376,-0.10791253841717666,-0.1424888753229872,1.5667994320520733,-0.30111518243997987,1.8459424393187207,-0.2832385860448953,-1.3117306703903504,2.4496613605694386,-2.425193190684344,1.2059486289837344,1.8695432160167267,1.0296274822176772,-0.26542599868242417,-0.5208177336190014,0.47705956297724367,-1.096295452188383,0.19301386899346543,-0.1424888753229872,0.04479749007284595,0.14408985151272588,-0.596278947334594,0.14408985151272588,1.2590315225380515,-0.33706243340680064,-0.07357327446040215,-0.2832385860448953,1.4915153034770001,-0.26542599868242417,0.8184979173823138,0.02805701137235168,-0.1424888753229872,3.1543688124281597,-0.07357327446040215,1.0845146796370766,-0.24767692023999524,2.0547236877093185,1.8695432160167267,0.3997325317718629,2.2667166943530197,0.02805701137235168,-0.558403728184664,0.6875712647067221,-0.1424888753229872,0.30536674022651894,-1.7500104946959263,-0.2832385860448953,1.2192696206606266,1.2590315225380515,-0.373271876429598,2.916265686588943,3.107549151128594,-0.2832385860448953,0.2735187641595761,-0.35513411913799386,-0.5395748804972572,-0.10791253841717666,-4.1411192303358,0.4616874064468927,2.077431989617715,-0.8099892376198776,0.11120892157867891,-0.30111518243997987,-0.8298890333091614,0.06148252180205109,-0.1424888753229872,-0.6922649775615227,-0.07357327446040215,-2.1012974711813244,2.7982738550861823,-0.30111518243997987
| 3,430
|
Biliary tract abnormality
| 12
| 29
| 3.01312
| 0.002586
|
Q10713,P07602,Q9NZJ7,Q5XKP0,O43681,O95202,Q9UJW0,O96028,P09601,Q14108,Q14739,P04062
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
292,38,341,626,553,401,180,334,59,60,222,30
|
869,553,401,334,1534,30,38,59,1223,983,2353,804,2699,2079,1194,292,1857,2626,60,222,626,1834,685,1346,341,1023,180,1350,2815
|
0.43080383738421585,0.7896879996375533,1.0981470112960925,1.2590315225380515,-0.005591913085313469,3.0603364192521147,3.0127233121243298,2.54410242985927,0.17675834803240076,0.33701658189477507,-0.40974773902190176,0.4923857069491886,-0.6729168790091554,-0.26542599868242417,0.19301386899346543,1.3765499068522848,-0.15986707294579158,-0.6153265492951593,2.5336885717746562,1.6164042064007391,0.7022834886797121,-0.1424888753229872,0.6431811538013191,0.11120892157867891,1.2590315225380515,0.32121625895525563,1.798428045397234,0.11120892157867891,-0.7507725016906376
| 3,430
|
Lipid catabolic process
| 31
| 87
| 3.005458
| 0.002652
|
O75874,O14678,Q9NP80,O14734,Q06520,P06865,P06280,Q16134,P50897,Q8NCG7,O15254,P04062,P23786,Q8N2A8,O14975,Q8WTV0,Q9BWD1,P28288,Q8NHP8,A1L0T0,Q15067,Q2T9J0,P17900,O43808,Q709F0,Q99519,O95470,Q8NCC3,A8MXV4,Q13510,P35610
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
1,257,264,391,144,268,275,533,22,534,285,30,33,164,424,169,304,555,53,54,319,320,66,573,457,340,86,91,350,250,252
|
54,350,3427,257,391,424,285,573,2381,1,3323,86,30,895,3421,1606,275,268,1358,3287,3358,1535,3028,1444,66,2504,2261,33,2354,2434,555,3344,3011,252,3168,2183,948,740,929,2776,1884,1258,1058,2079,22,1364,1194,2510,2837,2187,2511,144,1968,1969,250,319,2391,533,1720,625,320,3291,2193,457,1172,1128,164,1494,1457,1623,91,534,53,169,2338,340,1837,1085,1047,3422,304,2128,264,3173,591,1386,2660
|
2.6267135515683826,1.2325569767034361,-4.650483787176411,1.4661818634308703,1.125305736257329,1.04340337414266,1.3894476706931538,0.7607169539788241,-0.4280869276823581,3.92901774642917,-1.6306790060749776,2.321161071650228,3.0603364192521147,0.41529180787632924,-3.7873509360750597,-0.03946755021715677,1.4151493408700357,1.4279535786684734,0.09468784334280253,-1.4913543909405875,-1.8477085071425041,-0.005591913085313469,-0.971515740451046,0.04479749007284595,2.4918352621956807,-0.5208177336190014,-0.35513411913799386,3.0318170762153325,-0.40974773902190176,-0.4649705794159142,0.7896879996375533,-1.7500104946959263,-0.9510285615071858,1.4915153034770001,-1.1599171531024435,-0.31905629408571334,0.36847097049977656,0.5833929390939195,0.3841256925736641,-0.7311921139115007,-0.1773059016141884,0.1604504658814682,0.2894676887918951,-0.26542599868242417,3.191546309151074,0.09468784334280253,0.19301386899346543,-0.5208177336190014,-0.7901703605422196,-0.31905629408571334,-0.5208177336190014,1.9513415899455118,-0.2123673195994045,-0.2123673195994045,1.5041368739934033,1.2984956621256847,-0.4280869276823581,0.8328430643605732,-0.0907134950668146,0.7022834886797121,1.2984956621256847,-1.4913543909405875,-0.31905629408571334,0.9741576934609325,0.20921739577808898,0.24146991514915547,1.8577557582221775,0.02805701137235168,0.04479749007284595,-0.03946755021715677,2.277649032464161,0.8328430643605732,2.6369536602330523,1.8459424393187207,-0.3914762369552328,1.2590315225380515,-0.1424888753229872,0.2735187641595761,0.30536674022651894,-3.980876334866757,1.3506596827179598,-0.2832385860448953,1.4534696782308594,-1.1599171531024435,0.7461703883999292,0.09468784334280253,-0.6344483133432426
| 3,430
|
Organophosphate ester transport
| 14
| 25
| 3.003749
| 0.002667
|
Q6NUK1,P08183,P12236,Q4KMQ2,Q9BZF1,P61916,Q8WTV0,Q14108,Q9H2D1,Q8TB61,P12235,P22059,Q9BSK2,Q96GC9
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
580,159,418,163,458,512,169,60,49,55,213,316,61,188
|
2796,573,736,159,213,418,316,2261,1914,512,2511,60,163,580,730,996,55,169,188,1552,61,458,3380,49,1734
|
-0.7507725016906376,0.7607169539788241,0.5833929390939195,1.8695432160167267,1.641034754600386,1.057143066123191,1.2984956621256847,-0.35513411913799386,-0.1948058268211105,0.8756421363992508,-0.5208177336190014,2.5336885717746562,1.8577557582221775,0.7607169539788241,0.5984052493734849,0.33701658189477507,2.606176282501621,1.8459424393187207,1.7625145060761207,-0.005591913085313469,2.5336885717746562,0.9741576934609325,-2.049460345691425,2.7383268943293446,-0.0907134950668146
| 3,430
|
Sphingolipid biosynthetic process
| 9
| 15
| 2.992749
| 0.002765
|
Q06136,O15269,Q9P035,O15270,O60512,O95470,Q13510,Q96G23,P04062
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
258,286,294,295,18,86,250,124,30
|
286,295,18,86,30,316,501,2511,258,250,951,124,591,294,1734
|
1.3894476706931538,1.3636206339195902,3.237676205824806,2.321161071650228,3.0603364192521147,1.2984956621256847,0.8898304908049921,-0.5208177336190014,1.4661818634308703,1.5041368739934033,0.36847097049977656,2.066089721766653,0.7461703883999292,1.3765499068522848,-0.0907134950668146
| 3,430
|
Mitochondrial myopathy
| 10
| 28
| 2.987879
| 0.002809
|
Q9Y6M9,Q9NPL8,Q9NP80,Q86Y39,P03886,Q96CU9,O43676,P12235,O60313,P00403
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
326,325,264,168,73,274,21,213,375,28
|
892,21,375,1441,413,978,1442,606,28,73,213,2639,3031,3152,951,168,1493,935,274,937,2518,1212,264,325,749,2024,1601,326
|
0.41529180787632924,3.200802504118346,1.1657819605638418,0.04479749007284595,1.07084676596474,0.33701658189477507,0.04479749007284595,0.7169539114401163,3.0698107589013315,2.4178172840822203,1.641034754600386,-0.6344483133432426,-0.971515740451046,-1.1386163266404463,0.36847097049977656,1.8459424393187207,0.02805701137235168,0.3841256925736641,1.4279535786684734,0.3841256925736641,-0.5208177336190014,0.19301386899346543,1.4534696782308594,1.2853737321434007,0.5833929390939195,-0.22999085661134913,-0.02250118346835699,1.2853737321434007
| 3,430
|
Meiotic cell cycle process
| 19
| 46
| 2.987849
| 0.002809
|
P46379,Q14674,O14965,Q13315,O14777,P30153,Q9Y5A9,O43683,Q12768,Q9BZD4,Q96GX5,Q9Y2W6,P42695,O15360,O95067,Q92791,Q9BTX1,O94901,P53350
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
256,637,521,400,528,795,817,539,550,422,684,48,439,454,709,219,92,368,502
|
528,521,454,539,2283,1097,1185,368,709,1778,1779,3064,795,3086,1416,1911,439,256,2361,805,502,1573,2671,2463,2005,914,1297,550,400,637,1719,1487,2366,1376,1172,219,1683,684,92,1242,422,1689,1595,2916,48,817
|
0.8471486580863727,0.861414936766202,0.9741576934609325,0.8184979173823138,-0.373271876429598,0.25751962221115077,0.19301386899346543,1.179204988513675,0.6133738705970863,-0.12517084870498654,-0.12517084870498654,-1.0127520150653435,0.5076661391022604,-1.0335027512907717,0.06148252180205109,-0.1948058268211105,1.0158151806848401,1.47886368568901,-0.40974773902190176,0.4923857069491886,0.8898304908049921,-0.02250118346835699,-0.6536448751928122,-0.4835161673691688,-0.22999085661134913,0.3997325317718629,0.14408985151272588,0.8041129767098191,1.1117439633053623,0.6875712647067221,-0.0907134950668146,0.02805701137235168,-0.40974773902190176,0.09468784334280253,0.20921739577808898,1.6287336796515217,-0.07357327446040215,0.6431811538013191,2.277649032464161,0.17675834803240076,1.057143066123191,-0.07357327446040215,-0.02250118346835699,-0.8498704751461239,2.748363067010926,0.4923857069491886
| 3,430
|
Alternative mrna splicing via spliceosome
| 18
| 45
| 2.987438
| 0.002813
|
Q00839,P62995,P31483,P52756,P14866,P17844,P23246,Q06787,P51116,O95391,P51114,Q08211,Q96MU7,Q9UHX1,P98175,Q9BWF3,Q07666,P38159
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
609,576,322,395,772,773,584,203,100,234,84,622,664,118,281,411,448,351
|
3138,2663,2143,1810,234,981,772,773,584,2527,322,351,1512,84,100,1012,395,576,281,609,203,448,1397,622,2417,1167,2935,1423,2189,1168,1518,1492,1341,881,1343,1500,664,1758,411,2064,118,957,2544,836,2281
|
-1.117409393747407,-0.6536448751928122,-0.30111518243997987,-0.1424888753229872,1.5667994320520733,0.33701658189477507,0.5380910558331444,0.5380910558331444,0.7461703883999292,-0.5395748804972572,1.2853737321434007,1.2325569767034361,0.01126068031324202,2.3319852246797077,2.211724229893288,0.32121625895525563,1.125305736257329,0.7607169539788241,1.402314093228658,0.7169539114401163,1.7021191193583658,1.001966258000303,0.07811250742307049,0.7022834886797121,-0.4464943548499513,0.20921739577808898,-0.8699343008139493,0.06148252180205109,-0.31905629408571334,0.20921739577808898,0.01126068031324202,0.02805701137235168,0.11120892157867891,0.43080383738421585,0.11120892157867891,0.02805701137235168,0.65802036299361,-0.10791253841717666,1.0845146796370766,-0.24767692023999524,2.1113172784145564,0.36847097049977656,-0.5395748804972572,0.47705956297724367,-0.35513411913799386
| 3,430
|
Sterol binding
| 11
| 18
| 2.982375
| 0.00286
|
P30536,Q9BZF1,P61916,P21796,Q96SU4,P45880,O15118,P35610,P22059,Q14849,Q14108
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
2,458,512,9,564,15,109,252,316,27,60
|
109,566,2070,2146,9,316,2261,2,252,15,512,60,27,564,1591,1553,458,3380
|
2.1784605959005607,0.7752227411673067,-0.26542599868242417,-0.30111518243997987,3.489279818123242,1.2984956621256847,-0.35513411913799386,3.92901774642917,1.4915153034770001,3.2925394092933984,0.8756421363992508,2.5336885717746562,3.0792691433168833,0.7896879996375533,-0.02250118346835699,-0.005591913085313469,0.9741576934609325,-2.049460345691425
| 3,430
|
Abnormality of pulmonary circulation
| 14
| 31
| 2.980424
| 0.002878
|
O75844,Q6NUK1,P51970,O14678,O96000,P03886,P51798,P14854,P01889,Q8IZA0,Q9NZ08,Q14108,P00403,P04062
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
32,580,386,257,606,73,524,363,369,93,185,60,28,30
|
257,2145,32,1390,606,28,369,1534,73,30,1255,363,1119,3127,2073,2925,2000,1541,796,524,386,60,3275,680,2676,580,93,1624,2132,185,3043
|
1.4661818634308703,-0.30111518243997987,3.050846065270086,0.07811250742307049,0.7169539114401163,3.0698107589013315,1.179204988513675,-0.005591913085313469,2.4178172840822203,3.0603364192521147,0.1604504658814682,1.1925938145223307,0.24146991514915547,-1.096295452188383,-0.26542599868242417,-0.8699343008139493,-0.22999085661134913,-0.005591913085313469,0.5076661391022604,0.861414936766202,1.1388325289942267,2.5336885717746562,-1.445808727840182,0.6431811538013191,-0.6536448751928122,0.7607169539788241,2.2667166943530197,-0.03946755021715677,-0.2832385860448953,1.774512395985724,-0.971515740451046
| 3,430
|
Organic acid transmembrane transporter activity
| 11
| 19
| 2.977741
| 0.002904
|
O75746,P08183,O14975,Q9UBX3,Q9Y619,P53985,Q9H2D1,Q9UJS0,P30825,Q96NB2,Q9BQT8
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
692,159,424,13,45,271,49,708,402,410,157
|
424,692,839,159,1567,402,1100,271,696,950,2193,410,157,49,1409,942,13,708,45
|
1.04340337414266,0.6282990804246098,0.4616874064468927,1.8695432160167267,-0.02250118346835699,1.0981470112960925,0.25751962221115077,1.4279535786684734,0.6282990804246098,0.36847097049977656,-0.31905629408571334,1.0845146796370766,1.8813049364421908,2.7383268943293446,0.07811250742307049,0.3841256925736641,3.391761695054266,0.6282990804246098,2.7982738550861823
| 3,430
|
Protein transporter activity
| 6
| 15
| 2.97701
| 0.002911
|
Q9Y5J9,Q9HD20,Q9NS69,Q99595,O60830,Q9Y584
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
193,35,7,78,20,119
|
204,20,1098,1443,910,1014,621,900,1040,78,35,7,547,119,193
|
1.6777690135569574,3.2100435371001237,0.25751962221115077,0.04479749007284595,0.3997325317718629,0.32121625895525563,0.7022834886797121,0.41529180787632924,0.30536674022651894,2.3750691920218543,3.0318170762153325,3.602417135580486,0.8184979173823138,2.1113172784145564,1.750489731196436
| 3,430
|
Glycosphingolipid metabolism
| 9
| 16
| 2.975098
| 0.002929
|
P10619,P17900,P07602,P16278,Q9NZJ7,P06865,P06280,Q13510,P04062
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
226,66,38,43,341,268,275,250,30
|
856,553,30,275,268,38,1358,226,983,43,66,250,340,2830,591,341
|
0.44626893355334946,0.7896879996375533,3.0603364192521147,1.4151493408700357,1.4279535786684734,3.0127233121243298,0.09468784334280253,1.6040461907838122,0.33701658189477507,2.9065277890482055,2.4918352621956807,1.5041368739934033,1.2590315225380515,-0.7704316844994457,0.7461703883999292,1.2590315225380515
| 3,430
|
Endocytic vesicle
| 20
| 86
| 2.971971
| 0.002959
|
P10321,Q15907,Q14457,O00461,Q8WTV0,P33176,P14625,Q9Y487,Q14108,Q969Q5,Q5VYK3,P08670,Q03519,Q16625,Q03518,Q93050,P42345,P13473,P01889,P04439
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
393,276,287,31,169,425,300,175,60,323,71,335,215,346,218,220,353,237,369,244
|
1737,857,31,907,1071,926,3179,2574,1186,2071,1702,369,1314,244,1221,656,335,3126,3233,393,982,646,1509,1994,237,300,1147,3064,2641,2076,425,353,1192,912,2461,1364,3206,1011,986,2292,2644,1292,1149,2186,1259,3341,2804,1783,1450,218,215,1578,1422,2704,1337,1669,60,1321,287,2390,2330,1583,2237,276,2628,346,1674,449,71,2335,902,169,3074,220,323,1270,1272,588,2520,2875,1348,956,175,734,2405,2214
|
-0.10791253841717666,0.44626893355334946,3.050846065270086,0.3997325317718629,0.2735187641595761,0.3841256925736641,-1.1813127889529935,-0.5773048800496771,0.19301386899346543,-0.26542599868242417,-0.0907134950668146,1.179204988513675,0.1276761298241045,1.5292904957224467,0.17675834803240076,0.65802036299361,1.2590315225380515,-1.096295452188383,-1.3117306703903504,1.125305736257329,0.33701658189477507,0.6728169776242082,0.01126068031324202,-0.22999085661134913,1.554325783520826,1.3506596827179598,0.22536929144369766,-1.0127520150653435,-0.6344483133432426,-0.26542599868242417,1.04340337414266,1.2192696206606266,0.19301386899346543,0.3997325317718629,-0.4835161673691688,0.09468784334280253,-1.2460779206914567,0.32121625895525563,0.33701658189477507,-0.373271876429598,-0.6344483133432426,0.14408985151272588,0.22536929144369766,-0.31905629408571334,0.1604504658814682,-1.725900749051077,-0.7507725016906376,-0.12517084870498654,0.04479749007284595,1.6287336796515217,1.641034754600386,-0.02250118346835699,0.06148252180205109,-0.6729168790091554,0.11120892157867891,-0.07357327446040215,2.5336885717746562,0.1276761298241045,1.3894476706931538,-0.4280869276823581,-0.3914762369552328,-0.02250118346835699,-0.33706243340680064,1.4151493408700357,-0.6153265492951593,1.2458108826688405,-0.07357327446040215,1.001966258000303,2.4390671593224433,-0.3914762369552328,0.41529180787632924,1.8459424393187207,-1.0127520150653435,1.6287336796515217,1.2853737321434007,0.1604504658814682,0.1604504658814682,0.7461703883999292,-0.5208177336190014,-0.8099892376198776,0.11120892157867891,0.36847097049977656,1.8103460646896083,0.5984052493734849,-0.4280869276823581,-0.31905629408571334
| 3,430
|
Response to oxidative stress
| 26
| 103
| 2.968757
| 0.00299
|
O75874,Q9NP80,Q15165,O43169,P16615,Q8N0U8,O95168,Q16134,P04083,Q15392,Q99720,P04062,Q14457,O95831,O75306,P30519,Q969S3,Q9Y5Z4,P46108,P09601,Q6NUK1,Q15118,P54646,P00374,P05067,O75569
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
1,264,139,14,269,17,529,533,148,23,26,30,287,414,413,44,560,50,429,59,580,329,75,76,205,342
|
2876,892,2816,1738,14,413,2284,2547,342,1,1507,529,1703,414,76,980,30,148,3161,1877,2225,205,2525,1608,1284,1117,59,2036,2147,3301,2856,269,3257,896,1569,1415,584,2771,3048,774,1881,2800,3344,2356,2181,2598,44,3251,1813,1190,2506,804,2000,820,429,2699,2360,3282,1012,75,2153,3194,1165,2511,621,931,899,1228,1647,287,329,139,1078,23,533,580,1546,1425,1172,17,2565,827,2536,560,1000,3000,1499,2849,2470,1380,2243,3387,26,1242,1688,264,705,2494,1245,1308,666,2137,50
|
-0.8298890333091614,0.41529180787632924,-0.7704316844994457,-0.10791253841717666,3.3468758304359083,1.07084676596474,-0.373271876429598,-0.558403728184664,1.2458108826688405,3.92901774642917,0.01126068031324202,0.8471486580863727,-0.0907134950668146,1.07084676596474,2.3964848636249685,0.33701658189477507,3.0603364192521147,1.904751655596212,-1.1599171531024435,-0.1773059016141884,-0.33706243340680064,1.6777690135569574,-0.5395748804972572,-0.03946755021715677,0.14408985151272588,0.24146991514915547,2.54410242985927,-0.24767692023999524,-0.30111518243997987,-1.5373416114687155,-0.8099892376198776,1.4279535786684734,-1.3782981393570042,0.41529180787632924,-0.02250118346835699,0.06148252180205109,0.7461703883999292,-0.7311921139115007,-0.992089953515064,0.5380910558331444,-0.1773059016141884,-0.7507725016906376,-1.7500104946959263,-0.40974773902190176,-0.31905629408571334,-0.596278947334594,2.8378826071016987,-1.3560056220962575,-0.1424888753229872,0.19301386899346543,-0.5208177336190014,0.4923857069491886,-0.22999085661134913,0.47705956297724367,1.0296274822176772,-0.6729168790091554,-0.40974773902190176,-1.468526945815869,0.32121625895525563,2.4071614359087854,-0.30111518243997987,-1.2028041638743916,0.20921739577808898,-0.5208177336190014,0.7022834886797121,0.3841256925736641,0.41529180787632924,0.17675834803240076,-0.0564914375226667,1.3894476706931538,1.2722190787348595,1.9744867066455778,0.2735187641595761,3.1543688124281597,0.8328430643605732,0.7607169539788241,-0.005591913085313469,0.06148252180205109,0.20921739577808898,3.256023162941908,-0.558403728184664,0.47705956297724367,-0.5395748804972572,0.7896879996375533,0.33701658189477507,-0.9306276139125141,0.02805701137235168,-0.7901703605422196,-0.4835161673691688,0.09468784334280253,-0.33706243340680064,-2.1012974711813244,3.107549151128594,0.17675834803240076,-0.07357327446040215,1.4534696782308594,0.6282990804246098,-0.5021316919187672,0.17675834803240076,0.14408985151272588,0.65802036299361,-0.2832385860448953,2.68787200548125
| 3,430
|
Lipid binding
| 26
| 156
| 2.968336
| 0.002994
|
Q9BQE5,P30536,P21796,P38435,O00560,P45880,O00264,P50897,P04083,Q14849,O15254,P04062,O14773,P07602,Q8WTV0,Q9UM22,Q14108,P22059,A6NIH7,Q15067,O43292,Q96L92,Q8NCC3,O15173,O15118,P35610
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
0,2,9,136,266,15,143,22,148,27,285,30,162,38,169,51,60,316,62,319,194,330,91,99,109,252
|
856,62,143,1662,1559,1389,266,2796,162,907,794,109,99,285,2767,194,960,375,3179,1699,1355,2455,1603,566,3338,2070,2071,2032,1639,30,148,607,1952,38,2596,2146,1359,2768,3180,2108,2411,1222,1509,3279,1994,1477,2073,9,316,2261,3181,2287,2640,841,3101,2,1479,3167,252,1572,136,15,2749,1511,1914,22,912,3033,2929,1964,1573,2387,1750,512,1714,2607,1198,2648,988,503,3035,1422,531,427,1201,2704,2089,3015,60,2155,27,2389,319,3130,1583,3245,1896,2116,2097,2868,2275,1681,2678,91,2468,169,1082,1083,1977,2730,1427,1270,2758,330,2684,564,1937,848,517,2887,3209,3205,0,2830,887,1591,1553,458,1555,3380,640,748,815,1382,2892,341,1214,2104,3278,1530,2250,51,3375,2689,1632,2315,633,3222,2919,734,2317,891,2140,670,924,1558
|
0.44626893355334946,2.5128016570172145,1.9513415899455118,-0.07357327446040215,-0.02250118346835699,0.07811250742307049,1.4407269703301229,-0.7507725016906376,1.8577557582221775,0.3997325317718629,0.5076661391022604,2.1784605959005607,2.211724229893288,1.3894476706931538,-0.7311921139115007,1.738437938975464,0.3527680424371989,1.1657819605638418,-1.1813127889529935,-0.0907134950668146,0.09468784334280253,-0.4835161673691688,-0.03946755021715677,0.7752227411673067,-1.725900749051077,-0.26542599868242417,-0.26542599868242417,-0.24767692023999524,-0.0564914375226667,3.0603364192521147,1.904751655596212,0.7169539114401163,-0.2123673195994045,3.0127233121243298,-0.596278947334594,-0.30111518243997987,0.09468784334280253,-0.7311921139115007,-1.1813127889529935,-0.2832385860448953,-0.4464943548499513,0.17675834803240076,0.01126068031324202,-1.468526945815869,-0.22999085661134913,0.02805701137235168,-0.26542599868242417,3.489279818123242,1.2984956621256847,-0.35513411913799386,-1.1813127889529935,-0.373271876429598,-0.6344483133432426,0.4616874064468927,-1.0543430004362901,3.92901774642917,0.02805701137235168,-1.1599171531024435,1.4915153034770001,-0.02250118346835699,1.9975331678372859,3.2925394092933984,-0.7116898323792509,0.01126068031324202,-0.1948058268211105,3.191546309151074,0.3997325317718629,-0.971515740451046,-0.8699343008139493,-0.2123673195994045,-0.02250118346835699,-0.4280869276823581,-0.10791253841717666,0.8756421363992508,-0.0907134950668146,-0.596278947334594,0.19301386899346543,-0.6344483133432426,0.33701658189477507,0.8898304908049921,-0.971515740451046,0.06148252180205109,0.8471486580863727,1.04340337414266,0.19301386899346543,-0.6729168790091554,-0.26542599868242417,-0.9510285615071858,2.5336885717746562,-0.30111518243997987,3.0792691433168833,-0.4280869276823581,1.2984956621256847,-1.096295452188383,-0.02250118346835699,-1.333816816277065,-0.1773059016141884,-0.2832385860448953,-0.26542599868242417,-0.8099892376198776,-0.35513411913799386,-0.07357327446040215,-0.6536448751928122,2.277649032464161,-0.4835161673691688,1.8459424393187207,0.2735187641595761,0.2735187641595761,-0.2123673195994045,-0.6922649775615227,0.06148252180205109,0.1604504658814682,-0.7116898323792509,1.2722190787348595,-0.6536448751928122,0.7896879996375533,-0.1948058268211105,0.4616874064468927,0.8756421363992508,-0.8298890333091614,-1.2460779206914567,-1.2243922216969028,3.937153403770652,-0.7704316844994457,0.43080383738421585,-0.02250118346835699,-0.005591913085313469,0.9741576934609325,-0.005591913085313469,-2.049460345691425,0.6875712647067221,0.5833929390939195,0.4923857069491886,0.09468784334280253,-0.8298890333091614,1.2590315225380515,0.19301386899346543,-0.26542599868242417,-1.445808727840182,0.01126068031324202,-0.33706243340680064,2.677725710562994,-1.9727749634114744,-0.6536448751928122,-0.03946755021715677,-0.373271876429598,0.7022834886797121,-1.267862233870033,-0.8498704751461239,0.5984052493734849,-0.373271876429598,0.43080383738421585,-0.2832385860448953,0.65802036299361,0.3997325317718629,-0.005591913085313469
| 3,430
|
Abnormal myocardium morphology
| 41
| 186
| 2.967404
| 0.003003
|
P48735,Q9H061,Q96CU9,Q13423,P06280,O43676,P08236,P00403,Q9P0J0,P04062,O75306,P23786,Q99797,P53701,Q86Y39,P16278,P50402,Q9NWS8,Q9Y4P3,P10253,Q9NZ08,Q9NVI7,Q14108,Q9Y6M9,Q9NPL8,P03886,O15360,P15586,Q99519,P54802,P12235,Q00325,P22626,O43772,Q9Y2Z2,O76024,Q96RL7,P13473,P14854,P01889,O60313
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
10,12,274,146,275,21,279,28,158,30,413,33,290,167,168,43,431,182,313,311,185,443,60,326,325,73,454,206,340,87,213,214,343,468,488,477,358,237,363,369,375
|
906,2173,892,1950,454,21,2922,2350,468,1142,375,1441,413,978,1056,1442,3248,477,1777,1390,2033,1252,3286,606,28,369,1534,73,858,30,3421,1606,275,1566,2819,279,2035,723,1117,1568,981,311,213,237,1475,363,1538,206,1743,43,3010,896,3029,2639,1415,2073,693,1665,343,3062,33,2772,3031,3049,3011,1747,1478,2775,1224,3167,2926,2413,2990,2078,2748,1710,739,948,786,1148,1395,2507,775,1075,10,796,1258,3152,431,1058,2079,2483,167,87,2387,2510,1290,1195,3360,2862,2992,2879,1034,2484,214,1891,2934,741,2556,742,146,3071,1670,60,1451,3275,2113,2299,1078,1673,625,3132,951,1262,822,626,525,1171,1620,168,3313,1493,1206,2197,935,2872,1043,1834,1378,1459,1624,274,972,358,937,2312,340,1837,290,586,3041,1325,494,1087,2518,1242,3377,1942,12,1179,1408,1730,3262,816,1660,850,3371,325,2022,443,182,2133,185,749,158,866,2712,1350,488,2024,2917,2025,313,3043,1698,326
|
0.3997325317718629,-0.31905629408571334,0.41529180787632924,-0.2123673195994045,0.9741576934609325,3.200802504118346,-0.8699343008139493,-0.40974773902190176,0.9462000577616902,0.22536929144369766,1.1657819605638418,0.04479749007284595,1.07084676596474,0.33701658189477507,0.2894676887918951,0.04479749007284595,-1.3560056220962575,0.9321647887240839,-0.12517084870498654,0.07811250742307049,-0.24767692023999524,0.1604504658814682,-1.4913543909405875,0.7169539114401163,3.0698107589013315,1.179204988513675,-0.005591913085313469,2.4178172840822203,0.44626893355334946,3.0603364192521147,-3.7873509360750597,-0.03946755021715677,1.4151493408700357,-0.02250118346835699,-0.7704316844994457,1.402314093228658,-0.24767692023999524,0.5984052493734849,0.24146991514915547,-0.02250118346835699,0.33701658189477507,1.3246420617522143,1.641034754600386,1.554325783520826,0.02805701137235168,1.1925938145223307,-0.005591913085313469,1.6777690135569574,-0.10791253841717666,2.9065277890482055,-0.9510285615071858,0.41529180787632924,-0.971515740451046,-0.6344483133432426,0.06148252180205109,-0.26542599868242417,0.6282990804246098,-0.07357327446040215,1.2458108826688405,-1.0127520150653435,3.0318170762153325,-0.7311921139115007,-0.971515740451046,-0.992089953515064,-0.9510285615071858,-0.10791253841717666,0.02805701137235168,-0.7311921139115007,0.17675834803240076,-1.1599171531024435,-0.8699343008139493,-0.4464943548499513,-0.9306276139125141,-0.26542599868242417,-0.7116898323792509,-0.0907134950668146,0.5833929390939195,0.36847097049977656,0.522901157152449,0.22536929144369766,0.07811250742307049,-0.5208177336190014,0.5380910558331444,0.2735187641595761,3.454011813127605,0.5076661391022604,0.1604504658814682,-1.1386163266404463,1.0296274822176772,0.2894676887918951,-0.26542599868242417,-0.5021316919187672,1.8459424393187207,2.321161071650228,-0.4280869276823581,-0.5208177336190014,0.14408985151272588,0.19301386899346543,-1.8477085071425041,-0.8099892376198776,-0.9306276139125141,-0.8298890333091614,0.30536674022651894,-0.5021316919187672,1.641034754600386,-0.1773059016141884,-0.8699343008139493,0.5833929390939195,-0.558403728184664,0.5833929390939195,1.9280968875332776,-1.0127520150653435,-0.07357327446040215,2.5336885717746562,0.04479749007284595,-1.445808727840182,-0.2832385860448953,-0.373271876429598,0.2735187641595761,-0.07357327446040215,0.7022834886797121,-1.096295452188383,0.36847097049977656,0.1604504658814682,0.47705956297724367,0.7022834886797121,0.861414936766202,0.20921739577808898,-0.03946755021715677,1.8459424393187207,-1.5605037593216007,0.02805701137235168,0.19301386899346543,-0.31905629408571334,0.3841256925736641,-0.8099892376198776,0.30536674022651894,-0.1424888753229872,0.09468784334280253,0.04479749007284595,-0.03946755021715677,1.4279535786684734,0.3527680424371989,1.2192696206606266,0.3841256925736641,-0.373271876429598,1.2590315225380515,-0.1424888753229872,1.3894476706931538,0.7461703883999292,-0.971515740451046,0.1276761298241045,0.9180915884762,0.2735187641595761,-0.5208177336190014,0.17675834803240076,-1.9981963448778324,-0.1948058268211105,3.4362955117330025,0.20921739577808898,0.07811250742307049,-0.0907134950668146,-1.3782981393570042,0.4923857069491886,-0.0564914375226667,0.4616874064468927,-1.9474917631058593,1.2853737321434007,-0.22999085661134913,1.0158151806848401,1.7864835322979642,-0.2832385860448953,1.774512395985724,0.5833929390939195,1.8813049364421908,0.44626893355334946,-0.6729168790091554,0.11120892157867891,0.9321647887240839,-0.22999085661134913,-0.8498704751461239,-0.22999085661134913,1.3246420617522143,-0.971515740451046,-0.07357327446040215,1.2853737321434007
| 3,430
|
Steroid biosynthetic process
| 21
| 49
| 2.966984
| 0.003007
|
P30536,Q53GQ0,O14734,Q15392,Q14849,P37268,O14975,Q96SU4,P28288,O75477,P22059,P54646,Q16850,O75845,Q15800,Q14739,P05023,P16435,Q14534,Q13510,O76062
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
2,262,391,23,27,166,424,564,555,566,316,75,210,470,88,222,607,231,122,250,382
|
391,424,566,470,382,2070,1876,607,3301,2697,3141,231,316,2261,1997,555,2,166,2776,753,1855,3383,75,2081,3312,250,3254,122,222,27,3220,23,1299,2190,1169,88,210,262,1623,3000,564,1837,2128,1553,3380,1659,632,767,760
|
1.125305736257329,1.04340337414266,0.7752227411673067,0.9462000577616902,1.1523245386286525,-0.26542599868242417,-0.1773059016141884,0.7169539114401163,-1.5373416114687155,-0.6729168790091554,-1.117409393747407,1.5792439505261,1.2984956621256847,-0.35513411913799386,-0.22999085661134913,0.7896879996375533,3.92901774642917,1.8459424393187207,-0.7311921139115007,0.5683366593475094,-0.15986707294579158,-2.0753063910430853,2.4071614359087854,-0.26542599868242417,-1.5605037593216007,1.5041368739934033,-1.3560056220962575,2.077431989617715,1.6164042064007391,3.0792691433168833,-1.267862233870033,3.1543688124281597,0.14408985151272588,-0.31905629408571334,0.20921739577808898,2.310315469590055,1.6655522802639968,1.4534696782308594,-0.03946755021715677,-0.9306276139125141,0.7896879996375533,-0.1424888753229872,-0.2832385860448953,-0.005591913085313469,-2.049460345691425,-0.0564914375226667,0.7022834886797121,0.5532361269354006,0.5683366593475094
| 3,430
|
Hexosyltransferase activity
| 21
| 36
| 2.965516
| 0.003022
|
P46976,P06865,O60512,P04062,Q2TAA5,Q8N4A0,P46977,Q10472,Q96L58,O43909,O60762,Q6ZXV5,Q04446,Q9BT22,P04844,Q8TCJ2,Q13126,Q8NAT1,P04843,O43505,O60568
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
775,268,18,30,288,172,430,456,339,837,605,233,741,494,362,628,113,115,872,752,376
|
2107,2767,752,837,18,376,605,1356,30,872,362,1566,268,1358,1955,1475,1224,775,430,1296,741,875,456,113,288,233,1723,172,115,1266,628,339,494,1138,3424,1556
|
-0.2832385860448953,-0.7311921139115007,0.5683366593475094,0.4616874064468927,3.237676205824806,1.1657819605638418,0.7169539114401163,0.09468784334280253,3.0603364192521147,0.43080383738421585,1.1925938145223307,-0.02250118346835699,1.4279535786684734,0.09468784334280253,-0.2123673195994045,0.02805701137235168,0.17675834803240076,0.5380910558331444,1.0296274822176772,0.14408985151272588,0.5833929390939195,0.43080383738421585,0.9741576934609325,2.167327425815136,1.3894476706931538,1.5792439505261,-0.0907134950668146,1.8341031346457968,2.156171440265243,0.1604504658814682,0.7022834886797121,1.2590315225380515,0.9180915884762,0.24146991514915547,-4.1411192303358,-0.005591913085313469
| 3,430
|
Nuclear inner membrane
| 12
| 23
| 2.963382
| 0.003043
|
O75844,O76062,P62995,P43243,Q9H1E5,Q9UH99,P50402,O94901,Q99720,Q8IXM6,Q14739,Q14728
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
32,382,576,585,171,434,431,368,26,156,222,638
|
32,382,368,1446,1395,585,431,2267,576,1227,1200,638,222,1676,661,156,2959,3000,26,1087,171,434,1470
|
3.050846065270086,1.1523245386286525,1.179204988513675,0.04479749007284595,0.07811250742307049,0.7461703883999292,1.0296274822176772,-0.35513411913799386,0.7607169539788241,0.17675834803240076,0.19301386899346543,0.6875712647067221,1.6164042064007391,-0.07357327446040215,0.65802036299361,1.8813049364421908,-0.8900812583352817,-0.9306276139125141,3.107549151128594,0.2735187641595761,1.8459424393187207,1.0296274822176772,0.04479749007284595
| 3,430
|
Aminoglycan metabolic process
| 7
| 15
| 2.96066
| 0.00307
|
Q7LGA3,P16278,P15586,Q9UL01,P06865,P54802,P08236
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
128,43,206,79,268,87,279
|
752,2546,1702,895,268,1358,279,206,43,87,1783,2046,128,339,79
|
0.5683366593475094,-0.558403728184664,-0.0907134950668146,0.41529180787632924,1.4279535786684734,0.09468784334280253,1.402314093228658,1.6777690135569574,2.9065277890482055,2.321161071650228,-0.12517084870498654,-0.24767692023999524,2.0547236877093185,1.2590315225380515,2.3750691920218543
| 3,430
|
Slc mediated transmembrane transport
| 12
| 20
| 2.955986
| 0.003117
|
P12236,P55011,P11166,Q9UBX3,Q70HW3,P53985,P35613,P30825,Q8TB61,P12235,Q9Y6M7,Q15043
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
418,574,676,13,16,271,270,402,55,213,548,191
|
736,1567,676,213,418,3166,402,270,1641,271,574,191,950,2193,16,55,1552,1409,13,548
|
0.5833929390939195,-0.02250118346835699,0.6431811538013191,1.641034754600386,1.057143066123191,-1.1599171531024435,1.0981470112960925,1.4279535786684734,-0.0564914375226667,1.4279535786684734,0.7607169539788241,1.750489731196436,0.36847097049977656,-0.31905629408571334,3.2651743542921823,2.606176282501621,-0.005591913085313469,0.07811250742307049,3.391761695054266,0.8184979173823138
| 3,430
|
Subsets and Splits
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