term
stringlengths 2
121
| overlap
int64 6
281
| setsize
int64 7
499
| score
float64 1.96
10.6
| pval
float64 0
0.05
| edge
stringlengths 41
1.97k
| type
stringclasses 5
values | subtype
stringclasses 24
values | subtype_key
stringclasses 24
values | edge_idxs
stringlengths 11
1.17k
| ann_idxs
stringlengths 19
2.31k
| ann_vals
stringlengths 124
9.94k
| sig_size
int64 2.2k
3.73k
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Phosphatase regulator activity
| 10
| 20
| 2.686066
| 0.00723
|
P35269,O14974,Q01105,Q12972,P78318,Q6IN85,P30154,Q16537,Q86XL3,Q8TF05
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
248,258,104,357,481,372,466,249,254,631
|
258,2020,1144,466,248,1831,481,104,357,2095,1403,2600,249,703,372,254,631,1850,1579,1135
|
1.246239474826163,-0.26880087001046804,0.170454792757679,0.8016379926908211,1.2951658620327071,-0.16466408850858408,0.776705446342711,2.113519207995092,1.0002037240901964,-0.2949128537598711,0.0421516914587663,-0.5577941570157251,1.2951658620327071,0.5007536343265028,0.9754688945658373,1.2707141738685634,0.576325735394843,-0.16466408850858408,-0.035180219401076525,0.1960292991597587
| 3,425
|
Protein insertion into membrane
| 13
| 33
| 2.682623
| 0.007305
|
Q7L5D6,Q8N8Q8,Q9Y5J7,Q15629,Q53H12,Q9NS69,Q8N4V1,P46379,O43681,O43402,Q9Y5J9,Q9Y584,O14737
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
195,292,233,135,453,72,401,47,427,465,218,60,157
|
157,465,427,1700,2067,2242,1097,2586,47,504,2594,827,1835,135,453,1408,195,401,2157,292,1470,2887,2315,72,2274,2826,2858,1378,60,2861,233,218,1379
|
1.683344653281223,0.8016379926908211,0.876285345323554,-0.11277994734734909,-0.2949128537598711,-0.3734383603785469,0.1960292991597587,-0.5577941570157251,3.0240574327600016,0.7517476513909233,-0.5577941570157251,0.39961706105910194,-0.16466408850858408,1.851429702113107,0.8265454114723118,0.0421516914587663,1.5142122212082996,0.9259261957288346,-0.3210563089295906,1.1481084899134386,0.01640387475979311,-0.7437855934072211,-0.3996773248018237,2.396698193300339,-0.3734383603785469,-0.6904742194938005,-0.7171125997850363,0.06787023399176167,2.7932266034927613,-0.7171125997850363,1.3683838826407642,1.417082700426686,0.06787023399176167
| 3,425
|
Degradation of gli1 by the proteasome
| 12
| 43
| 2.676481
| 0.00744
|
P28070,Q14997,Q06323,P28072,Q99436,Q9UL46,P49721,P28074,P20618,O00231,P25787,O00487
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
289,414,291,194,232,294,103,139,270,88,57,304
|
88,2670,304,2234,1543,1643,988,2793,1176,270,2759,57,1710,2722,1816,289,194,139,2346,1922,1605,1876,103,1824,2025,1104,506,1722,1503,2876,1107,291,2808,1188,414,1454,733,1366,232,1415,294,2003,1692
|
2.2318502116319068,-0.6107646440167533,1.098902204500058,-0.3734383603785469,-0.035180219401076525,-0.08688334071096061,0.2725833089167855,-0.6904742194938005,0.14485178548258162,1.1972206297942891,-0.6638702399151422,2.8163886227017083,-0.11277994734734909,-0.6373004507569276,-0.16466408850858408,1.1481084899134386,1.5142122212082996,1.827480517995054,-0.42594849699032294,-0.2166706010189041,-0.0610168199068948,-0.1906519624283154,2.113519207995092,-0.16466408850858408,-0.26880087001046804,0.1960292991597587,0.7517476513909233,-0.11277994734734909,-0.009373375282462895,-0.7437855934072211,0.1960292991597587,1.1481084899134386,-0.6904742194938005,0.14485178548258162,0.9011180973452062,0.01640387475979311,0.4755098070522078,0.06787023399176167,1.3683838826407642,0.0421516914587663,1.1481084899134386,-0.24272017828745532,-0.08688334071096061
| 3,425
|
Transcriptional regulation by runx3
| 10
| 41
| 2.638078
| 0.008338
|
P28070,P28072,Q06323,Q99436,Q9UL46,P49721,P28074,P20618,O00231,P25787
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
289,194,291,232,294,103,139,270,88,57
|
88,2670,304,2234,1543,1643,2976,1176,270,1391,2759,57,1710,2722,1816,289,194,139,1917,2346,2496,1922,1605,1876,103,1824,2025,1104,506,1722,1503,2876,291,2808,2403,1454,733,232,1415,294,1692
|
2.2318502116319068,-0.6107646440167533,1.098902204500058,-0.3734383603785469,-0.035180219401076525,-0.08688334071096061,-0.8240144161249287,0.14485178548258162,1.1972206297942891,0.0421516914587663,-0.6638702399151422,2.8163886227017083,-0.11277994734734909,-0.6373004507569276,-0.16466408850858408,1.1481084899134386,1.5142122212082996,1.827480517995054,-0.2166706010189041,-0.42594849699032294,-0.5049571593465545,-0.2166706010189041,-0.0610168199068948,-0.1906519624283154,2.113519207995092,-0.16466408850858408,-0.26880087001046804,0.1960292991597587,0.7517476513909233,-0.11277994734734909,-0.009373375282462895,-0.7437855934072211,1.1481084899134386,-0.6904742194938005,-0.4522520658646618,0.01640387475979311,0.4755098070522078,1.3683838826407642,0.0421516914587663,1.1481084899134386,-0.08688334071096061
| 3,425
|
Cdt1 association with the cdc6 orc origin complex
| 12
| 40
| 2.620949
| 0.008769
|
P28070,P28072,Q06323,Q9Y619,Q99436,Q9UL46,P49721,P28074,P20618,O00231,P25787,O00487
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
289,194,291,234,232,294,103,139,270,88,57,304
|
88,2670,304,2234,1543,3060,1643,1176,270,2759,57,1710,2722,1816,289,194,139,2346,1922,1605,1876,103,1824,2025,1104,506,1722,1503,2876,291,2808,414,1454,733,232,1415,3054,294,1692,234
|
2.2318502116319068,-0.6107646440167533,1.098902204500058,-0.3734383603785469,-0.035180219401076525,-0.9045626443840719,-0.08688334071096061,0.14485178548258162,1.1972206297942891,-0.6638702399151422,2.8163886227017083,-0.11277994734734909,-0.6373004507569276,-0.16466408850858408,1.1481084899134386,1.5142122212082996,1.827480517995054,-0.42594849699032294,-0.2166706010189041,-0.0610168199068948,-0.1906519624283154,2.113519207995092,-0.16466408850858408,-0.26880087001046804,0.1960292991597587,0.7517476513909233,-0.11277994734734909,-0.009373375282462895,-0.7437855934072211,1.1481084899134386,-0.6904742194938005,0.9011180973452062,0.01640387475979311,0.4755098070522078,1.3683838826407642,0.0421516914587663,-0.8776773707245988,1.1481084899134386,-0.08688334071096061,1.3683838826407642
| 3,425
|
Regulation of sodium ion transport
| 6
| 18
| 2.619392
| 0.008809
|
P46934,P31749,P05023,Q9HD47,O43865,Q96PU5
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
261,69,41,277,181,159
|
1333,1172,181,2334,41,1434,3268,69,261,891,344,2398,1031,1294,159,1522,277,1860
|
0.06787023399176167,0.14485178548258162,1.5626444707730802,-0.42594849699032294,3.1617288490354225,0.01640387475979311,-1.2027404258895786,2.4904786675716095,1.246239474826163,0.3488861372872074,1.0249143581417541,-0.4522520658646618,0.2470934090651916,0.0935596600019327,1.683344653281223,-0.009373375282462895,1.1972206297942891,-0.16466408850858408
| 3,425
|
Tnfr2 non canonical nf kb pathway
| 13
| 43
| 2.617809
| 0.00885
|
P28070,Q14997,Q06323,P28072,Q99436,Q9UL46,P49721,P28074,P20618,O15111,O00231,P25787,O00487
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
289,414,291,194,232,294,103,139,270,464,88,57,304
|
88,2670,304,2234,464,1543,1643,1176,270,2759,57,1710,2722,1816,289,194,139,2346,1922,1605,1876,103,1824,2025,1104,1347,506,1722,1503,2876,1107,291,3322,2808,1188,414,1454,2461,733,232,1415,294,1692
|
2.2318502116319068,-0.6107646440167533,1.098902204500058,-0.3734383603785469,0.8016379926908211,-0.035180219401076525,-0.08688334071096061,0.14485178548258162,1.1972206297942891,-0.6638702399151422,2.8163886227017083,-0.11277994734734909,-0.6373004507569276,-0.16466408850858408,1.1481084899134386,1.5142122212082996,1.827480517995054,-0.42594849699032294,-0.2166706010189041,-0.0610168199068948,-0.1906519624283154,2.113519207995092,-0.16466408850858408,-0.26880087001046804,0.1960292991597587,0.06787023399176167,0.7517476513909233,-0.11277994734734909,-0.009373375282462895,-0.7437855934072211,0.1960292991597587,1.1481084899134386,-1.367344786047239,-0.6904742194938005,0.14485178548258162,0.9011180973452062,0.01640387475979311,-0.4785882223380154,0.4755098070522078,1.3683838826407642,0.0421516914587663,1.1481084899134386,-0.08688334071096061
| 3,425
|
Hedgehog ligand biogenesis
| 12
| 41
| 2.606831
| 0.009138
|
P28070,Q14997,Q06323,P28072,Q99436,Q9UL46,P49721,P28074,P20618,O00231,P25787,O00487
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
289,414,291,194,232,294,103,139,270,88,57,304
|
88,2670,304,2234,1543,1643,2282,1176,270,2759,57,1710,2722,1816,289,194,139,2346,1922,1605,1876,103,1824,2025,2256,1104,506,1722,1503,2876,291,2808,414,1454,733,232,1415,878,916,294,1692
|
2.2318502116319068,-0.6107646440167533,1.098902204500058,-0.3734383603785469,-0.035180219401076525,-0.08688334071096061,-0.3996773248018237,0.14485178548258162,1.1972206297942891,-0.6638702399151422,2.8163886227017083,-0.11277994734734909,-0.6373004507569276,-0.16466408850858408,1.1481084899134386,1.5142122212082996,1.827480517995054,-0.42594849699032294,-0.2166706010189041,-0.0610168199068948,-0.1906519624283154,2.113519207995092,-0.16466408850858408,-0.26880087001046804,-0.3734383603785469,0.1960292991597587,0.7517476513909233,-0.11277994734734909,-0.009373375282462895,-0.7437855934072211,1.1481084899134386,-0.6904742194938005,0.9011180973452062,0.01640387475979311,0.4755098070522078,1.3683838826407642,0.0421516914587663,0.37426526772845303,0.3488861372872074,1.1481084899134386,-0.08688334071096061
| 3,425
|
Regulation of runx2 expression and activity
| 12
| 44
| 2.604474
| 0.009202
|
P28070,Q14997,Q06323,P28072,Q99436,Q9UL46,P49721,P28074,P20618,O00231,P25787,O00487
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
289,414,291,194,232,294,103,139,270,88,57,304
|
88,2670,304,2234,1543,1643,856,1176,270,2759,57,1710,2722,1816,289,194,139,2346,2798,1922,1605,1876,103,1285,1824,2025,1104,506,1722,1503,2876,1107,291,2808,2203,1188,414,1454,733,232,1415,294,2228,1692
|
2.2318502116319068,-0.6107646440167533,1.098902204500058,-0.3734383603785469,-0.035180219401076525,-0.08688334071096061,0.37426526772845303,0.14485178548258162,1.1972206297942891,-0.6638702399151422,2.8163886227017083,-0.11277994734734909,-0.6373004507569276,-0.16466408850858408,1.1481084899134386,1.5142122212082996,1.827480517995054,-0.42594849699032294,-0.6904742194938005,-0.2166706010189041,-0.0610168199068948,-0.1906519624283154,2.113519207995092,0.0935596600019327,-0.16466408850858408,-0.26880087001046804,0.1960292991597587,0.7517476513909233,-0.11277994734734909,-0.009373375282462895,-0.7437855934072211,0.1960292991597587,1.1481084899134386,-0.6904742194938005,-0.3472314167626071,0.14485178548258162,0.9011180973452062,0.01640387475979311,0.4755098070522078,1.3683838826407642,0.0421516914587663,1.1481084899134386,-0.3472314167626071,-0.08688334071096061
| 3,425
|
Sh3 domain binding
| 13
| 23
| 2.584531
| 0.009751
|
Q16204,P50570,Q96PU8,Q9NYB9,P50552,O75525,P46108,Q96JJ3,Q96D71,P62993,Q07666,Q9Y6W5,Q14185
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
221,344,325,461,672,164,477,653,594,587,507,332,674
|
665,164,3220,477,672,344,587,507,1293,674,2205,221,1732,1155,594,653,325,1205,2050,461,1319,1758,332
|
0.5259708094615214,1.6351293355923024,-1.093785539462249,0.776705446342711,0.5259708094615214,1.0249143581417541,0.6265756372169713,0.7517476513909233,0.0935596600019327,0.5259708094615214,-0.3472314167626071,1.3927445446390339,-0.11277994734734909,0.170454792757679,0.6265756372169713,0.551161465774754,1.0742634875654984,0.14485178548258162,-0.26880087001046804,0.8265454114723118,0.0935596600019327,-0.11277994734734909,1.0742634875654984
| 3,425
|
Organic acid transport
| 10
| 48
| 2.583744
| 0.009773
|
P33527,P31749,P14174,P08183,O43772,P23786,P30825,Q96H78,Q9BQT8,P31751
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
219,69,71,138,10,149,209,58,94,95
|
1333,563,884,10,3265,583,1706,2788,2333,3300,814,2386,2241,138,2387,932,71,149,1915,2636,209,69,95,2187,219,573,1823,2840,411,2197,2353,1353,1569,1457,2411,1790,3021,58,1992,2304,94,472,3262,3105,2001,547,922,234
|
0.06787023399176167,0.6516615278677587,0.3488861372872074,5.009094029804443,-1.2027404258895786,0.6265756372169713,-0.11277994734734909,-0.6904742194938005,-0.42594849699032294,-1.2848639936597672,0.39961706105910194,-0.4522520658646618,-0.3734383603785469,1.827480517995054,-0.4522520658646618,0.32347952895027443,2.467061710936354,1.7555075594715182,-0.2166706010189041,-0.5842626139461844,1.4413984485653908,2.4904786675716095,2.1845767415122475,-0.3472314167626071,1.3927445446390339,0.6516615278677587,-0.16466408850858408,-0.7171125997850363,0.9011180973452062,-0.3472314167626071,-0.42594849699032294,0.06787023399176167,-0.035180219401076525,0.01640387475979311,-0.4522520658646618,-0.1387068069964346,-0.8508280371004248,2.8163886227017083,-0.24272017828745532,-0.3996773248018237,2.2082232468714693,0.8016379926908211,-1.175444027337681,-0.9314840880697907,-0.24272017828745532,0.7017558262776622,0.3488861372872074,1.3683838826407642
| 3,425
|
Cellular response to radiation
| 11
| 48
| 2.581621
| 0.009834
|
P50570,P46934,P29692,Q9H1E3,P12956,Q96K76,Q06787,Q9C0C2,Q96RU2,P27544,P31751
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
344,261,7,301,17,55,370,124,92,279,95
|
2999,566,931,2976,857,3180,691,1230,1596,17,2245,1912,279,933,7,1097,95,2835,261,344,2540,1558,587,1928,1398,370,1563,1184,1665,728,415,2553,575,2732,1359,1193,2928,55,1305,2705,92,3173,124,301,1313,2620,1905,2751
|
-0.8508280371004248,0.6516615278677587,0.32347952895027443,-0.8240144161249287,0.37426526772845303,-1.0395362564915789,0.5007536343265028,0.11922012561949845,-0.0610168199068948,4.441103682259946,-0.3734383603785469,-0.2166706010189041,1.1726762745538093,0.32347952895027443,5.4400213336505425,0.1960292991597587,2.1845767415122475,-0.7171125997850363,1.246239474826163,1.0249143581417541,-0.5313590718804885,-0.035180219401076525,0.6265756372169713,-0.2166706010189041,0.0421516914587663,0.9754688945658373,-0.035180219401076525,0.14485178548258162,-0.08688334071096061,0.4755098070522078,0.9011180973452062,-0.5313590718804885,0.6516615278677587,-0.6373004507569276,0.06787023399176167,0.14485178548258162,-0.7704934153422345,2.8857686722684996,0.0935596600019327,-0.6107646440167533,2.2318502116319068,-1.012467779172713,1.994691867614015,1.1235171691084074,0.0935596600019327,-0.5577941570157251,-0.1906519624283154,-0.6373004507569276
| 3,425
|
The role of gtse1 in g2 m progression after g2 checkpoint
| 12
| 50
| 2.574548
| 0.010037
|
P28070,Q14997,Q06323,P28072,Q99436,Q9UL46,P49721,P28074,P20618,O00231,P25787,O00487
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
289,414,291,194,232,294,103,139,270,88,57,304
|
88,2670,304,2234,1543,1643,1762,408,2976,648,2242,2018,2137,1176,270,2759,57,1710,2722,1816,289,194,139,2346,1922,1605,1876,103,1824,2982,2025,1104,506,1722,1503,2876,1183,291,2808,1075,414,1454,676,733,232,1415,979,1473,294,1692
|
2.2318502116319068,-0.6107646440167533,1.098902204500058,-0.3734383603785469,-0.035180219401076525,-0.08688334071096061,-0.1387068069964346,0.9011180973452062,-0.8240144161249287,0.551161465774754,-0.3734383603785469,-0.26880087001046804,-0.3210563089295906,0.14485178548258162,1.1972206297942891,-0.6638702399151422,2.8163886227017083,-0.11277994734734909,-0.6373004507569276,-0.16466408850858408,1.1481084899134386,1.5142122212082996,1.827480517995054,-0.42594849699032294,-0.2166706010189041,-0.0610168199068948,-0.1906519624283154,2.113519207995092,-0.16466408850858408,-0.8240144161249287,-0.26880087001046804,0.1960292991597587,0.7517476513909233,-0.11277994734734909,-0.009373375282462895,-0.7437855934072211,0.14485178548258162,1.1481084899134386,-0.6904742194938005,0.2215754549719998,0.9011180973452062,0.01640387475979311,0.5259708094615214,0.4755098070522078,1.3683838826407642,0.0421516914587663,0.29804530062961365,0.01640387475979311,1.1481084899134386,-0.08688334071096061
| 3,425
|
Regulation of hmox1 expression and activity
| 12
| 46
| 2.567115
| 0.010255
|
P28070,Q14997,Q06323,P28072,Q99436,Q9UL46,P49721,P28074,P20618,O00231,P25787,O00487
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
289,414,291,194,232,294,103,139,270,88,57,304
|
88,2670,304,2234,1543,1643,1141,1176,1769,270,2759,57,1710,2722,1816,289,194,139,2346,1922,1605,1876,103,1824,2025,1104,506,1722,1503,2876,1107,1560,1398,291,2808,2203,1188,1931,414,1454,3371,733,232,1415,294,1692
|
2.2318502116319068,-0.6107646440167533,1.098902204500058,-0.3734383603785469,-0.035180219401076525,-0.08688334071096061,0.170454792757679,0.14485178548258162,-0.1387068069964346,1.1972206297942891,-0.6638702399151422,2.8163886227017083,-0.11277994734734909,-0.6373004507569276,-0.16466408850858408,1.1481084899134386,1.5142122212082996,1.827480517995054,-0.42594849699032294,-0.2166706010189041,-0.0610168199068948,-0.1906519624283154,2.113519207995092,-0.16466408850858408,-0.26880087001046804,0.1960292991597587,0.7517476513909233,-0.11277994734734909,-0.009373375282462895,-0.7437855934072211,0.1960292991597587,-0.035180219401076525,0.0421516914587663,1.1481084899134386,-0.6904742194938005,-0.3472314167626071,0.14485178548258162,-0.2166706010189041,0.9011180973452062,0.01640387475979311,-1.5890980607614524,0.4755098070522078,1.3683838826407642,0.0421516914587663,1.1481084899134386,-0.08688334071096061
| 3,425
|
Runx1 regulates transcription of genes involved in differentiation of hscs
| 12
| 42
| 2.56477
| 0.010324
|
P28070,P28072,Q06323,Q99436,Q9UL46,P49721,P28074,Q03164,P20618,O00231,P25787,O00487
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
289,194,291,232,294,103,139,345,270,88,57,304
|
88,2670,304,2234,1543,1643,1912,1176,270,2759,57,1710,2722,1816,289,194,139,2346,1922,1605,1876,103,1824,2025,1104,506,1722,1503,2876,3377,894,345,291,2808,414,1454,733,1366,232,1415,294,1692
|
2.2318502116319068,-0.6107646440167533,1.098902204500058,-0.3734383603785469,-0.035180219401076525,-0.08688334071096061,-0.2166706010189041,0.14485178548258162,1.1972206297942891,-0.6638702399151422,2.8163886227017083,-0.11277994734734909,-0.6373004507569276,-0.16466408850858408,1.1481084899134386,1.5142122212082996,1.827480517995054,-0.42594849699032294,-0.2166706010189041,-0.0610168199068948,-0.1906519624283154,2.113519207995092,-0.16466408850858408,-0.26880087001046804,0.1960292991597587,0.7517476513909233,-0.11277994734734909,-0.009373375282462895,-0.7437855934072211,-1.757207227272218,0.3488861372872074,1.0249143581417541,1.1481084899134386,-0.6904742194938005,0.9011180973452062,0.01640387475979311,0.4755098070522078,0.06787023399176167,1.3683838826407642,0.0421516914587663,1.1481084899134386,-0.08688334071096061
| 3,425
|
transporter
| 21
| 61
| 2.559236
| 0.01049
|
Q8N1F7,O60830,Q99595,O43772,Q567V2,Q99808,Q9NR77,Q96P70,Q8N8Q8,P53985,O15397,P41440,O43681,Q9Y584,Q92973,O43615,Q9H2D1,Q9Y619,O15321,Q6NXT4,Q9C0E2
|
Functions
|
Panther Protein class
|
panther_protein_class
|
385,5,8,10,11,656,544,542,292,411,550,573,427,60,458,73,472,234,606,485,639
|
852,1759,1427,1590,1280,606,550,73,427,10,5,2485,812,2080,1236,573,937,2725,2194,2913,2839,2840,411,2499,1101,1777,1103,2594,1564,1568,1835,11,3421,485,762,1936,385,292,3168,2106,873,910,458,2161,542,1680,8,655,656,3077,639,472,1008,841,544,2222,1374,1271,60,1423,234
|
0.37426526772845303,-0.1387068069964346,0.01640387475979311,-0.0610168199068948,0.0935596600019327,0.6014637492767998,0.676721548752089,2.373205898373848,0.876285345323554,5.009094029804443,5.738741189752724,-0.5049571593465545,0.39961706105910194,-0.2949128537598711,0.11922012561949845,0.6516615278677587,0.32347952895027443,-0.6373004507569276,-0.3472314167626071,-0.7704934153422345,-0.7171125997850363,-0.7171125997850363,0.9011180973452062,-0.5049571593465545,0.1960292991597587,-0.1387068069964346,0.1960292991597587,-0.5577941570157251,-0.035180219401076525,-0.035180219401076525,-0.16466408850858408,4.9005648800921815,-4.59846177611102,0.776705446342711,0.45023919311681804,-0.2166706010189041,0.950709756463659,1.1481084899134386,-1.012467779172713,-0.2949128537598711,0.37426526772845303,0.3488861372872074,0.8265454114723118,-0.3210563089295906,0.7017558262776622,-0.08688334071096061,5.160492534890691,0.551161465774754,0.551161465774754,-0.9045626443840719,0.576325735394843,0.8016379926908211,0.2725833089167855,0.39961706105910194,0.7017558262776622,-0.3472314167626071,0.06787023399176167,0.11922012561949845,2.7932266034927613,0.0421516914587663,1.3683838826407642
| 3,425
|
Predicted secreted proteins
| 11
| 58
| 2.542322
| 0.011012
|
P80303,Q9UM22,Q8WUJ1,Q15165,Q6UX07,P14174,Q02818,Q9UMX5,O60888,Q8NBM8,P43490
|
Functions
|
Protein Atlas Protein class
|
protein_atlas_protein_class
|
32,64,2,65,70,71,134,207,24,120,127
|
1698,1382,2752,24,778,1490,608,1494,814,266,2016,2490,2017,1646,2632,71,1388,3278,1069,1550,127,696,1609,892,3066,2546,32,787,3137,134,399,2596,1511,1930,3357,65,3046,70,680,120,1301,2,3225,795,2561,654,3102,1682,2111,2565,473,3378,405,881,2712,64,207,3086
|
-0.11277994734734909,0.0421516914587663,-0.6638702399151422,4.020104398305677,0.42494165677844037,-0.009373375282462895,0.6014637492767998,-0.009373375282462895,0.39961706105910194,1.2217416615359413,-0.26880087001046804,-0.5049571593465545,-0.26880087001046804,-0.08688334071096061,-0.5842626139461844,2.467061710936354,0.0421516914587663,-1.2300757093182833,0.2215754549719998,-0.035180219401076525,1.9231530513553758,0.5007536343265028,-0.0610168199068948,0.3488861372872074,-0.9045626443840719,-0.5313590718804885,3.480632910343951,0.42494165677844037,-0.9854364187655524,1.851429702113107,0.9259261957288346,-0.5577941570157251,-0.009373375282462895,-0.2166706010189041,-1.505627144578314,2.5839606371950574,-0.8776773707245988,2.4904786675716095,0.5259708094615214,2.0184975203635163,0.0935596600019327,6.056236239550033,-1.093785539462249,0.42494165677844037,-0.5313590718804885,0.551161465774754,-0.9314840880697907,-0.08688334071096061,-0.2949128537598711,-0.5313590718804885,0.8016379926908211,-1.757207227272218,0.9259261957288346,0.37426526772845303,-0.6107646440167533,2.6072850142580664,1.4656918868469564,-0.9045626443840719
| 3,425
|
Stabilization of p53
| 12
| 40
| 2.530324
| 0.011396
|
P28070,Q14997,Q06323,P28072,Q99436,Q9UL46,P49721,P28074,P20618,O00231,P25787,O00487
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
289,414,291,194,232,294,103,139,270,88,57,304
|
88,2670,304,2234,1543,1643,931,2976,1176,270,2759,57,1710,2722,1816,289,194,139,2346,2496,1922,1605,1876,103,1824,2025,1104,506,1722,1503,2876,291,2808,414,1454,733,232,1415,294,1692
|
2.2318502116319068,-0.6107646440167533,1.098902204500058,-0.3734383603785469,-0.035180219401076525,-0.08688334071096061,0.32347952895027443,-0.8240144161249287,0.14485178548258162,1.1972206297942891,-0.6638702399151422,2.8163886227017083,-0.11277994734734909,-0.6373004507569276,-0.16466408850858408,1.1481084899134386,1.5142122212082996,1.827480517995054,-0.42594849699032294,-0.5049571593465545,-0.2166706010189041,-0.0610168199068948,-0.1906519624283154,2.113519207995092,-0.16466408850858408,-0.26880087001046804,0.1960292991597587,0.7517476513909233,-0.11277994734734909,-0.009373375282462895,-0.7437855934072211,1.1481084899134386,-0.6904742194938005,0.9011180973452062,0.01640387475979311,0.4755098070522078,1.3683838826407642,0.0421516914587663,1.1481084899134386,-0.08688334071096061
| 3,425
|
G1 s dna damage checkpoints
| 12
| 41
| 2.528164
| 0.011466
|
P28070,Q14997,Q06323,P28072,Q99436,Q9UL46,P49721,P28074,P20618,O00231,P25787,O00487
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
289,414,291,194,232,294,103,139,270,88,57,304
|
88,2670,304,2234,1543,1643,931,2976,1176,270,1067,2759,57,1710,2722,1816,289,194,139,2346,2496,1922,1605,1876,103,1824,2025,1104,506,1722,1503,2876,291,2808,414,1454,733,232,1415,294,1692
|
2.2318502116319068,-0.6107646440167533,1.098902204500058,-0.3734383603785469,-0.035180219401076525,-0.08688334071096061,0.32347952895027443,-0.8240144161249287,0.14485178548258162,1.1972206297942891,0.2215754549719998,-0.6638702399151422,2.8163886227017083,-0.11277994734734909,-0.6373004507569276,-0.16466408850858408,1.1481084899134386,1.5142122212082996,1.827480517995054,-0.42594849699032294,-0.5049571593465545,-0.2166706010189041,-0.0610168199068948,-0.1906519624283154,2.113519207995092,-0.16466408850858408,-0.26880087001046804,0.1960292991597587,0.7517476513909233,-0.11277994734734909,-0.009373375282462895,-0.7437855934072211,1.1481084899134386,-0.6904742194938005,0.9011180973452062,0.01640387475979311,0.4755098070522078,1.3683838826407642,0.0421516914587663,1.1481084899134386,-0.08688334071096061
| 3,425
|
Atpase coupled transmembrane transporter activity
| 9
| 25
| 2.520348
| 0.011724
|
P33527,P08183,P05023,Q9Y5K8,P36543,Q9HD20,Q15388,Q03519,Q9NQ11
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
219,138,41,438,554,186,443,440,31
|
884,1064,41,1434,568,138,2442,1233,2340,2185,1915,219,1342,554,2534,1105,895,757,440,443,186,31,2221,1323,438
|
0.3488861372872074,0.2215754549719998,3.1617288490354225,0.01640387475979311,0.6516615278677587,1.827480517995054,-0.4785882223380154,0.11922012561949845,-0.42594849699032294,-0.3472314167626071,-0.2166706010189041,1.3927445446390339,0.06787023399176167,0.676721548752089,-0.5313590718804885,0.1960292991597587,0.3488861372872074,0.45023919311681804,0.8514278226896782,0.8514278226896782,1.5626444707730802,3.5485562599914546,-0.3472314167626071,0.0935596600019327,0.876285345323554
| 3,425
|
Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1
| 14
| 48
| 2.516864
| 0.01184
|
P28070,Q14997,Q06323,P28072,Q99436,Q9UL46,P49721,P28074,Q96DE5,P20618,O00231,P25787,P61289,O00487
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
289,414,291,194,232,294,103,139,204,270,88,57,506,304
|
88,2670,304,2234,1279,1543,1643,1176,270,2759,57,1710,2722,1816,289,194,139,2077,2346,1922,1605,1876,103,1824,2982,2025,1104,506,1722,1503,2876,291,3394,1565,2808,2203,414,1454,733,204,232,1415,1083,1420,714,548,294,1692
|
2.2318502116319068,-0.6107646440167533,1.098902204500058,-0.3734383603785469,0.0935596600019327,-0.035180219401076525,-0.08688334071096061,0.14485178548258162,1.1972206297942891,-0.6638702399151422,2.8163886227017083,-0.11277994734734909,-0.6373004507569276,-0.16466408850858408,1.1481084899134386,1.5142122212082996,1.827480517995054,-0.2949128537598711,-0.42594849699032294,-0.2166706010189041,-0.0610168199068948,-0.1906519624283154,2.113519207995092,-0.16466408850858408,-0.8240144161249287,-0.26880087001046804,0.1960292991597587,0.7517476513909233,-0.11277994734734909,-0.009373375282462895,-0.7437855934072211,1.1481084899134386,-2.0410176675364773,-0.035180219401076525,-0.6904742194938005,-0.3472314167626071,0.9011180973452062,0.01640387475979311,0.4755098070522078,1.4656918868469564,1.3683838826407642,0.0421516914587663,0.2215754549719998,0.0421516914587663,0.5007536343265028,0.7017558262776622,1.1481084899134386,-0.08688334071096061
| 3,425
|
Calcium-binding protein
| 6
| 19
| 2.508295
| 0.012132
|
P80303,O43852,Q14257,Q02818,Q8N163,P41208
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
32,160,36,134,18,158
|
160,2760,1872,158,3036,2728,32,134,36,2151,2811,2658,592,18,1989,654,3076,283,1326
|
1.6592477259317628,-0.6638702399151422,-0.1906519624283154,1.683344653281223,-0.8776773707245988,-0.6373004507569276,3.480632910343951,1.851429702113107,3.3443526398316665,-0.3210563089295906,-0.6904742194938005,-0.5842626139461844,0.6265756372169713,4.441103682259946,-0.24272017828745532,0.551161465774754,-0.9045626443840719,1.1726762745538093,0.0935596600019327
| 3,425
|
Early endosome membrane
| 9
| 50
| 2.507426
| 0.012161
|
P30511,Q9BZF3,Q5VWJ9,Q8N4V1,Q9UEU0,Q92783,P51790,Q8IV08,Q9Y5X3
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
34,4,300,401,206,79,238,151,187
|
1695,2126,1137,774,927,930,2830,814,1227,535,1648,669,34,2590,238,991,1878,1882,1512,3161,430,1784,1404,1459,300,1360,1119,1987,151,401,79,1366,1946,2215,1205,1520,952,4,1162,1084,1630,3332,2782,206,617,2749,1635,2476,1132,187
|
-0.11277994734734909,-0.3210563089295906,0.170454792757679,0.42494165677844037,0.32347952895027443,0.32347952895027443,-0.7171125997850363,0.39961706105910194,0.11922012561949845,0.7017558262776622,-0.08688334071096061,0.5259708094615214,3.412565525129457,-0.5577941570157251,1.3440006150915877,0.2725833089167855,-0.1906519624283154,-0.1906519624283154,-0.009373375282462895,-1.012467779172713,0.876285345323554,-0.1387068069964346,0.0421516914587663,0.01640387475979311,1.1235171691084074,0.06787023399176167,0.1960292991597587,-0.24272017828745532,1.7314744805213913,0.9259261957288346,2.3026146253507402,0.06787023399176167,-0.2166706010189041,-0.3472314167626071,0.14485178548258162,-0.009373375282462895,0.32347952895027443,5.950692891080032,0.170454792757679,0.2215754549719998,-0.0610168199068948,-1.3949190573747474,-0.6638702399151422,1.4656918868469564,0.6014637492767998,-0.6373004507569276,-0.0610168199068948,-0.4785882223380154,0.1960292991597587,1.5626444707730802
| 3,425
|
Auf1 hnrnp d0 binds and destabilizes mrna
| 12
| 42
| 2.504906
| 0.012248
|
P28070,Q14997,Q06323,P28072,Q99436,Q9UL46,P49721,P28074,P20618,O00231,P25787,O00487
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
289,414,291,194,232,294,103,139,270,88,57,304
|
88,2670,304,2234,1543,1643,3179,2527,1231,1176,270,2759,57,1710,2722,1816,289,194,139,2346,1922,1605,1876,103,1824,2025,1104,506,1722,1503,2876,1446,291,2808,700,414,1454,733,232,1415,294,1692
|
2.2318502116319068,-0.6107646440167533,1.098902204500058,-0.3734383603785469,-0.035180219401076525,-0.08688334071096061,-1.0395362564915789,-0.5313590718804885,0.11922012561949845,0.14485178548258162,1.1972206297942891,-0.6638702399151422,2.8163886227017083,-0.11277994734734909,-0.6373004507569276,-0.16466408850858408,1.1481084899134386,1.5142122212082996,1.827480517995054,-0.42594849699032294,-0.2166706010189041,-0.0610168199068948,-0.1906519624283154,2.113519207995092,-0.16466408850858408,-0.26880087001046804,0.1960292991597587,0.7517476513909233,-0.11277994734734909,-0.009373375282462895,-0.7437855934072211,0.01640387475979311,1.1481084899134386,-0.6904742194938005,0.5007536343265028,0.9011180973452062,0.01640387475979311,0.4755098070522078,1.3683838826407642,0.0421516914587663,1.1481084899134386,-0.08688334071096061
| 3,425
|
Ion channel transport
| 12
| 30
| 2.503822
| 0.012286
|
Q9C0H2,Q9Y487,Q5EBL8,Q9Y5K8,P05023,P51790,Q13555,Q9HD20,Q4KMQ2,Q93050,Q9NQ11,Q96PU5
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
293,497,484,438,41,238,113,186,444,152,31,159
|
41,1434,2442,1233,2340,2185,3268,934,1342,554,2534,238,2398,1105,895,2917,113,730,444,484,152,159,2607,293,1522,186,31,1323,497,438
|
3.1617288490354225,0.01640387475979311,-0.4785882223380154,0.11922012561949845,-0.42594849699032294,-0.3472314167626071,-1.2027404258895786,0.32347952895027443,0.06787023399176167,0.676721548752089,-0.5313590718804885,1.3440006150915877,-0.4522520658646618,0.1960292991597587,0.3488861372872074,-0.7704934153422345,2.0422830000109147,0.4755098070522078,0.8514278226896782,0.776705446342711,1.7314744805213913,1.683344653281223,-0.5577941570157251,1.1481084899134386,-0.009373375282462895,1.5626444707730802,3.5485562599914546,0.0935596600019327,0.776705446342711,0.876285345323554
| 3,425
|
Proteasome, subunit alpha/beta [IPR001353]
| 6
| 14
| 2.487628
| 0.01286
|
P28072,Q99436,P49721,P28074,P20618,P25787
|
Sequence
|
InterPro Family
|
interpro_family
|
194,232,103,139,270,57
|
2234,270,2759,57,1710,2722,1816,289,194,139,1876,103,1104,232
|
-0.3734383603785469,1.1972206297942891,-0.6638702399151422,2.8163886227017083,-0.11277994734734909,-0.6373004507569276,-0.16466408850858408,1.1481084899134386,1.5142122212082996,1.827480517995054,-0.1906519624283154,2.113519207995092,0.1960292991597587,1.3683838826407642
| 3,425
|
Postaxial polydactyly
| 9
| 27
| 2.485813
| 0.012926
|
Q8NCM8,P61978,Q96J42,Q2M1P5,Q15125,O43924,Q10713,Q9Y366,O75665
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
133,356,140,299,46,82,346,52,150
|
2007,82,150,2065,988,2793,3204,1144,356,439,346,675,46,299,556,133,1364,2741,140,1416,840,1951,771,2173,2003,1536,52
|
-0.26880087001046804,2.255457712363717,1.7314744805213913,-0.2949128537598711,0.2725833089167855,-0.6904742194938005,-1.0666420944020525,0.170454792757679,1.0002037240901964,0.8514278226896782,1.0249143581417541,0.5259708094615214,3.047045185687798,1.1235171691084074,0.676721548752089,1.875358128951854,0.06787023399176167,-0.6373004507569276,1.827480517995054,0.0421516914587663,0.39961706105910194,-0.2166706010189041,0.45023919311681804,-0.3210563089295906,-0.24272017828745532,-0.009373375282462895,2.931934335739412
| 3,425
|
Antigen processing cross presentation
| 18
| 55
| 2.481773
| 0.013073
|
P28070,Q14997,P30511,Q06323,P28072,Q9UL46,Q9UIQ6,Q99436,P49721,P28074,P20618,Q9UBG0,O15111,O00231,P25787,P61289,O00487,Q03519
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
289,414,34,291,194,294,137,232,103,139,270,81,464,88,57,506,304,440
|
3059,88,2670,304,2234,464,1543,3402,1643,2830,1227,1646,535,1176,270,2759,57,1710,2722,2760,1816,289,194,139,2949,34,2346,1922,1605,1876,103,1824,2025,3037,1104,506,2594,1722,1503,2876,757,440,291,3336,2808,414,1454,733,232,1415,81,137,294,1692,719
|
-0.9045626443840719,2.2318502116319068,-0.6107646440167533,1.098902204500058,-0.3734383603785469,0.8016379926908211,-0.035180219401076525,-2.417293772180834,-0.08688334071096061,-0.7171125997850363,0.11922012561949845,-0.08688334071096061,0.7017558262776622,0.14485178548258162,1.1972206297942891,-0.6638702399151422,2.8163886227017083,-0.11277994734734909,-0.6373004507569276,-0.6638702399151422,-0.16466408850858408,1.1481084899134386,1.5142122212082996,1.827480517995054,-0.7972362829735179,3.412565525129457,-0.42594849699032294,-0.2166706010189041,-0.0610168199068948,-0.1906519624283154,2.113519207995092,-0.16466408850858408,-0.26880087001046804,-0.8776773707245988,0.1960292991597587,0.7517476513909233,-0.5577941570157251,-0.11277994734734909,-0.009373375282462895,-0.7437855934072211,0.45023919311681804,0.8514278226896782,1.1481084899134386,-1.42253413815144,-0.6904742194938005,0.9011180973452062,0.01640387475979311,0.4755098070522078,1.3683838826407642,0.0421516914587663,2.3026146253507402,1.851429702113107,1.1481084899134386,-0.08688334071096061,0.5007536343265028
| 3,425
|
Gmp metabolic process
| 6
| 18
| 2.476929
| 0.013252
|
P55263,Q00013,Q9UDY2,P20839,P00813,P12268
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
128,525,406,42,14,118
|
662,1281,1910,14,1546,118,42,2342,989,1773,521,3007,128,525,897,1666,1690,406
|
0.5259708094615214,0.0935596600019327,-0.2166706010189041,4.748071870065068,-0.035180219401076525,2.0184975203635163,3.1617288490354225,-0.42594849699032294,0.2725833089167855,-0.1387068069964346,0.72676448575094,-0.8508280371004248,1.9231530513553758,0.72676448575094,0.3488861372872074,-0.08688334071096061,-0.08688334071096061,0.9259261957288346
| 3,425
|
Metalloprotease
| 10
| 26
| 2.474892
| 0.013328
|
Q9BYT8,Q9UIQ6,O75976,P55786,O43847,Q7Z2K6,P09960,Q5JRX3,P42892,O00487
|
Functions
|
Protein Atlas Molecular function
|
protein_atlas_molecular_function
|
389,137,449,19,394,311,117,509,25,304
|
304,394,2753,566,449,117,2135,1388,25,1825,19,509,3046,311,949,837,2047,877,389,2565,842,1997,1806,881,137,1060
|
1.098902204500058,0.9259261957288346,-0.6638702399151422,0.6516615278677587,0.8265454114723118,2.0184975203635163,-0.3210563089295906,0.0421516914587663,3.9531504082961226,-0.16466408850858408,4.419074039669878,0.7517476513909233,-0.8776773707245988,1.098902204500058,0.32347952895027443,0.39961706105910194,-0.26880087001046804,0.37426526772845303,0.950709756463659,-0.5313590718804885,0.39961706105910194,-0.24272017828745532,-0.1387068069964346,0.37426526772845303,1.851429702113107,0.2470934090651916
| 3,425
|
Motile cilium
| 6
| 33
| 2.472237
| 0.013427
|
P09622,Q8NCM8,P05023,P10809,Q9Y366,O75665
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
99,133,41,15,52,150
|
1333,150,1709,814,41,1434,2388,99,1968,15,988,2793,753,158,2682,1874,2398,2687,2289,3388,1931,1513,1355,443,416,1466,133,1004,840,1266,2856,52,2378
|
0.06787023399176167,1.7314744805213913,-0.11277994734734909,0.39961706105910194,3.1617288490354225,0.01640387475979311,-0.4522520658646618,2.160910618443281,-0.24272017828745532,4.726233902247758,0.2725833089167855,-0.6904742194938005,0.45023919311681804,1.683344653281223,-0.6107646440167533,-0.1906519624283154,-0.4522520658646618,-0.6107646440167533,-0.3996773248018237,-1.9269323014404063,-0.2166706010189041,-0.009373375282462895,0.06787023399176167,0.8514278226896782,0.9011180973452062,0.01640387475979311,1.875358128951854,0.2725833089167855,0.39961706105910194,0.11922012561949845,-0.7171125997850363,2.931934335739412,-0.42594849699032294
| 3,425
|
Negative regulation of response to external stimulus
| 15
| 51
| 2.466506
| 0.013644
|
P19474,P80303,P28070,P30511,P32119,P14174,P46108,P00813,Q9UMX5,Q07021,O43657,Q96G23,Q16539,Q9H000,Q9UIV1
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
624,32,289,34,609,71,477,14,207,399,366,215,575,422,257
|
1382,662,366,1065,1490,14,2830,2489,1227,1812,71,1096,624,2759,289,2345,34,609,2795,2083,477,2981,2197,2727,939,1505,32,2766,1398,399,1035,1727,575,1983,905,2928,1002,3073,1794,215,1366,1305,838,422,1855,2617,257,207,804,1134,1862
|
0.0421516914587663,0.5259708094615214,0.9754688945658373,0.2215754549719998,-0.009373375282462895,4.748071870065068,-0.7171125997850363,-0.5049571593465545,0.11922012561949845,-0.16466408850858408,2.467061710936354,0.1960292991597587,0.576325735394843,-0.6638702399151422,1.1481084899134386,-0.42594849699032294,3.412565525129457,0.6014637492767998,-0.6904742194938005,-0.2949128537598711,0.776705446342711,-0.8240144161249287,-0.3472314167626071,-0.6373004507569276,0.32347952895027443,-0.009373375282462895,3.480632910343951,-0.6638702399151422,0.0421516914587663,0.9259261957288346,0.2470934090651916,-0.11277994734734909,0.6516615278677587,-0.24272017828745532,0.3488861372872074,-0.7704934153422345,0.2725833089167855,-0.9045626443840719,-0.1387068069964346,1.4413984485653908,0.06787023399176167,0.0935596600019327,0.39961706105910194,0.9011180973452062,-0.16466408850858408,-0.5577941570157251,1.2707141738685634,1.4656918868469564,0.42494165677844037,0.1960292991597587,-0.16466408850858408
| 3,425
|
Cilium assembly
| 20
| 69
| 2.456388
| 0.014034
|
Q8NCM8,Q9NV70,O75665,O95684,P41208,P04350,Q9Y366,O94927,O43805,Q92973,Q9H6D7,P49368,Q8IYI6,O43924,Q10713,Q13561,Q15154,Q96CS2,A6NIH7,O75935
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
133,142,150,29,158,408,52,182,62,458,460,451,323,82,346,347,358,114,122,123
|
476,122,772,62,82,809,150,3111,123,182,29,408,648,780,2242,988,2793,1766,1496,2675,1144,2250,158,2682,2023,451,2396,1923,2982,2914,862,1240,1028,3271,1183,723,346,968,347,1075,1782,790,1036,1355,358,676,943,905,323,133,1891,1047,458,736,114,2741,1895,836,2854,979,1473,840,460,1951,142,3333,1215,52,1539
|
0.776705446342711,1.994691867614015,0.42494165677844037,2.7236336326597668,2.255457712363717,0.39961706105910194,1.7314744805213913,-0.9584419344202308,1.994691867614015,1.5626444707730802,3.7064919694139826,0.9011180973452062,0.551161465774754,0.42494165677844037,-0.3734383603785469,0.2725833089167855,-0.6904742194938005,-0.1387068069964346,-0.009373375282462895,-0.6107646440167533,0.170454792757679,-0.3734383603785469,1.683344653281223,-0.6107646440167533,-0.26880087001046804,0.8265454114723118,-0.4522520658646618,-0.2166706010189041,-0.8240144161249287,-0.7704934153422345,0.37426526772845303,0.11922012561949845,0.2470934090651916,-1.2027404258895786,0.14485178548258162,0.4755098070522078,1.0249143581417541,0.29804530062961365,1.0249143581417541,0.2215754549719998,-0.1387068069964346,0.42494165677844037,0.2470934090651916,0.06787023399176167,1.0002037240901964,0.5259708094615214,0.32347952895027443,0.3488861372872074,1.0742634875654984,1.875358128951854,-0.1906519624283154,0.2470934090651916,0.8265454114723118,0.4755098070522078,2.0422830000109147,-0.6373004507569276,-0.1906519624283154,0.39961706105910194,-0.7171125997850363,0.29804530062961365,0.01640387475979311,0.39961706105910194,0.8265454114723118,-0.2166706010189041,1.827480517995054,-1.3949190573747474,0.14485178548258162,2.931934335739412,-0.009373375282462895
| 3,425
|
Translation initiation factor activity
| 18
| 37
| 2.453842
| 0.014134
|
Q92905,Q15056,Q9NR50,Q9Y262,P05198,Q7Z478,P55010,O43583,O75822,O00303,P60228,Q14240,P49770,Q9ULC4,P23588,O60841,Q9UI10,O15372
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
949,868,365,495,857,832,45,552,333,115,893,239,467,424,307,775,644,748
|
115,1865,748,552,1223,775,1383,333,857,1228,1497,307,2445,1502,467,45,2086,2350,893,940,1395,1446,1185,2204,997,1401,239,868,1464,832,949,1800,365,2376,644,424,495
|
2.0184975203635163,-0.1906519624283154,0.45023919311681804,0.676721548752089,0.11922012561949845,0.42494165677844037,0.0421516914587663,1.0496009088870837,0.37426526772845303,0.11922012561949845,-0.009373375282462895,1.098902204500058,-0.4785882223380154,-0.009373375282462895,0.8016379926908211,3.070015851916738,-0.2949128537598711,-0.42594849699032294,0.3488861372872074,0.32347952895027443,0.0421516914587663,0.01640387475979311,0.14485178548258162,-0.3472314167626071,0.2725833089167855,0.0421516914587663,1.3440006150915877,0.37426526772845303,0.01640387475979311,0.39961706105910194,0.32347952895027443,-0.1387068069964346,1.0002037240901964,-0.42594849699032294,0.576325735394843,0.9011180973452062,0.776705446342711
| 3,425
|
Proteasome core complex
| 6
| 15
| 2.448683
| 0.014338
|
P28072,Q99436,P49721,P28074,P20618,P25787
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
194,232,103,139,270,57
|
2234,270,2759,57,1710,2722,1816,289,194,139,1876,103,1104,733,232
|
-0.3734383603785469,1.1972206297942891,-0.6638702399151422,2.8163886227017083,-0.11277994734734909,-0.6373004507569276,-0.16466408850858408,1.1481084899134386,1.5142122212082996,1.827480517995054,-0.1906519624283154,2.113519207995092,0.1960292991597587,0.4755098070522078,1.3683838826407642
| 3,425
|
Receptor
| 13
| 47
| 2.44674
| 0.014415
|
Q99523,Q8WTV0,O15118,Q9NS69,P35613,Q9UBG0,P60033,P55899,P24390,Q99720,Q9UKV5,P30825,P20645
|
Functions
|
Protein Atlas Molecular function
|
protein_atlas_molecular_function
|
489,130,380,72,227,81,272,398,236,20,278,209,342
|
1331,1382,1089,380,498,2486,1494,856,2386,648,3154,1911,1967,1647,2756,2978,1022,1388,342,2395,236,1649,209,227,398,272,2546,826,1930,1296,1883,675,1457,941,130,1943,1157,489,3347,20,72,2225,81,278,1274,2278,2714
|
0.06787023399176167,0.0421516914587663,0.1960292991597587,0.950709756463659,0.7517476513909233,-0.5049571593465545,-0.009373375282462895,0.37426526772845303,-0.4522520658646618,0.551161465774754,-1.012467779172713,-0.2166706010189041,-0.24272017828745532,-0.08688334071096061,-0.6638702399151422,-0.8240144161249287,0.2470934090651916,0.0421516914587663,1.0249143581417541,-0.4522520658646618,1.3440006150915877,-0.08688334071096061,1.4413984485653908,1.3683838826407642,0.9259261957288346,1.1972206297942891,-0.5313590718804885,0.39961706105910194,-0.2166706010189041,0.0935596600019327,-0.1906519624283154,0.5259708094615214,0.01640387475979311,0.32347952895027443,1.9231530513553758,-0.2166706010189041,0.170454792757679,0.776705446342711,-1.4501903172702728,4.374972711166257,2.396698193300339,-0.3472314167626071,2.3026146253507402,1.1972206297942891,0.11922012561949845,-0.3734383603785469,-0.6107646440167533
| 3,425
|
Pcp ce pathway
| 10
| 51
| 2.444986
| 0.014486
|
P28070,P28072,Q06323,Q99436,Q9UL46,P49721,P28074,P20618,O00231,P25787
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
289,194,291,232,294,103,139,270,88,57
|
88,2670,304,2234,1543,1643,1491,2488,2580,815,1595,988,1176,270,2759,57,1710,2722,1816,289,194,139,2795,2346,1922,1605,1876,103,1824,625,2025,699,1104,506,1722,1503,2876,1973,1927,1880,291,2808,1884,414,1454,733,2775,232,1415,294,1692
|
2.2318502116319068,-0.6107646440167533,1.098902204500058,-0.3734383603785469,-0.035180219401076525,-0.08688334071096061,-0.009373375282462895,-0.5049571593465545,-0.5577941570157251,0.39961706105910194,-0.0610168199068948,0.2725833089167855,0.14485178548258162,1.1972206297942891,-0.6638702399151422,2.8163886227017083,-0.11277994734734909,-0.6373004507569276,-0.16466408850858408,1.1481084899134386,1.5142122212082996,1.827480517995054,-0.6904742194938005,-0.42594849699032294,-0.2166706010189041,-0.0610168199068948,-0.1906519624283154,2.113519207995092,-0.16466408850858408,0.576325735394843,-0.26880087001046804,0.5007536343265028,0.1960292991597587,0.7517476513909233,-0.11277994734734909,-0.009373375282462895,-0.7437855934072211,-0.24272017828745532,-0.2166706010189041,-0.1906519624283154,1.1481084899134386,-0.6904742194938005,-0.1906519624283154,0.9011180973452062,0.01640387475979311,0.4755098070522078,-0.6638702399151422,1.3683838826407642,0.0421516914587663,1.1481084899134386,-0.08688334071096061
| 3,425
|
Cellular response to hypoxia
| 12
| 41
| 2.441316
| 0.014634
|
P28070,Q14997,Q06323,P28072,Q99436,Q9UL46,P49721,P28074,P20618,O00231,P25787,O00487
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
289,414,291,194,232,294,103,139,270,88,57,304
|
88,2670,304,2234,1543,1643,1176,270,2759,57,1710,2722,1816,289,194,139,2346,1922,1605,1876,103,1824,2025,1104,506,1722,1503,2876,291,2808,1244,414,1454,3042,733,232,1415,800,294,1692,3057
|
2.2318502116319068,-0.6107646440167533,1.098902204500058,-0.3734383603785469,-0.035180219401076525,-0.08688334071096061,0.14485178548258162,1.1972206297942891,-0.6638702399151422,2.8163886227017083,-0.11277994734734909,-0.6373004507569276,-0.16466408850858408,1.1481084899134386,1.5142122212082996,1.827480517995054,-0.42594849699032294,-0.2166706010189041,-0.0610168199068948,-0.1906519624283154,2.113519207995092,-0.16466408850858408,-0.26880087001046804,0.1960292991597587,0.7517476513909233,-0.11277994734734909,-0.009373375282462895,-0.7437855934072211,1.1481084899134386,-0.6904742194938005,0.11922012561949845,0.9011180973452062,0.01640387475979311,-0.8776773707245988,0.4755098070522078,1.3683838826407642,0.0421516914587663,0.42494165677844037,1.1481084899134386,-0.08688334071096061,-0.8776773707245988
| 3,425
|
Metalloprotease
| 12
| 40
| 2.430895
| 0.015062
|
Q9BYT8,P22695,Q8IYS1,Q9UIQ6,P20839,Q10713,P55786,O00303,Q7Z2K6,P12268,P42892,O00487
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
389,288,360,137,42,346,19,115,311,118,25,304
|
115,304,748,394,2753,566,1494,118,2135,1388,42,288,3360,3156,25,1824,1825,19,346,1616,2205,2923,509,3046,2772,311,360,3100,949,2512,837,2047,877,1744,389,642,1806,881,137,1060
|
2.0184975203635163,1.098902204500058,0.45023919311681804,0.9259261957288346,-0.6638702399151422,0.6516615278677587,-0.009373375282462895,2.0184975203635163,-0.3210563089295906,0.0421516914587663,3.1617288490354225,1.1481084899134386,-1.53340838923115,-1.012467779172713,3.9531504082961226,-0.16466408850858408,-0.16466408850858408,4.419074039669878,1.0249143581417541,-0.0610168199068948,-0.3472314167626071,-0.7704934153422345,0.7517476513909233,-0.8776773707245988,-0.6638702399151422,1.098902204500058,1.0002037240901964,-0.9314840880697907,0.32347952895027443,-0.5049571593465545,0.39961706105910194,-0.26880087001046804,0.37426526772845303,-0.11277994734734909,0.950709756463659,0.576325735394843,-0.1387068069964346,0.37426526772845303,1.851429702113107,0.2470934090651916
| 3,425
|
EF-hand domain pair [IPR011992]
| 9
| 50
| 2.426697
| 0.015237
|
P80303,O75071,O43852,Q14257,Q02818,Q9NWM8,Q8N163,Q9BRK5,P41208
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
32,193,160,36,134,48,18,283,158
|
1172,160,193,3031,1706,1493,887,2526,692,2946,2674,2246,1096,934,1872,158,1873,891,2728,32,134,1562,1149,789,36,2955,2151,1669,2363,2658,2558,3120,592,18,1737,798,1989,594,654,3076,283,1162,1630,1417,48,2473,3263,547,1755,337
|
0.14485178548258162,1.6592477259317628,1.5142122212082996,-0.8776773707245988,-0.11277994734734909,-0.009373375282462895,0.3488861372872074,-0.5313590718804885,0.5007536343265028,-0.7972362829735179,-0.6107646440167533,-0.3734383603785469,0.1960292991597587,0.32347952895027443,-0.1906519624283154,1.683344653281223,-0.1906519624283154,0.3488861372872074,-0.6373004507569276,3.480632910343951,1.851429702113107,-0.035180219401076525,0.170454792757679,0.42494165677844037,3.3443526398316665,-0.7972362829735179,-0.3210563089295906,-0.08688334071096061,-0.42594849699032294,-0.5842626139461844,-0.5313590718804885,-0.9584419344202308,0.6265756372169713,4.441103682259946,-0.11277994734734909,0.42494165677844037,-0.24272017828745532,0.6265756372169713,0.551161465774754,-0.9045626443840719,1.1726762745538093,0.170454792757679,-0.0610168199068948,0.0421516914587663,3.0240574327600016,-0.4785882223380154,-1.175444027337681,0.7017558262776622,-0.11277994734734909,1.0496009088870837
| 3,425
|
SLC superfamily of solute carriers
| 20
| 52
| 2.424622
| 0.015324
|
Q9HC21,O43772,Q9UJS0,P53985,Q15043,Q5T1Q4,P41440,Q9BSK2,Q70HW3,Q96H78,Q8IXU6,Q9Y6M7,O14975,Q6NT16,Q9H2D1,P30825,Q9BQT8,Q9Y619,Q6NXT4,O00400
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
268,10,547,411,430,49,573,313,54,58,61,331,563,75,472,209,94,234,485,235
|
235,563,10,3265,1706,1493,2944,2387,932,1814,2492,209,573,2840,411,2197,2916,2353,430,1457,49,3421,75,2363,485,2411,762,54,61,1410,1044,1045,593,58,1992,2304,656,94,313,2112,1521,472,3262,3105,3332,268,2426,2001,547,234,2785,331
|
1.3440006150915877,0.6516615278677587,5.009094029804443,-1.2027404258895786,-0.11277994734734909,-0.009373375282462895,-0.7972362829735179,-0.4522520658646618,0.32347952895027443,-0.16466408850858408,-0.5049571593465545,1.4413984485653908,0.6516615278677587,-0.7171125997850363,0.9011180973452062,-0.3472314167626071,-0.7704934153422345,-0.42594849699032294,0.876285345323554,0.01640387475979311,2.9780304239200897,-4.59846177611102,2.3496945877831767,-0.42594849699032294,0.776705446342711,-0.4522520658646618,0.45023919311681804,2.8857686722684996,2.7468491737605234,0.0421516914587663,0.2470934090651916,0.2470934090651916,0.6265756372169713,2.8163886227017083,-0.24272017828745532,-0.3996773248018237,0.551161465774754,2.2082232468714693,1.098902204500058,-0.2949128537598711,-0.009373375282462895,0.8016379926908211,-1.175444027337681,-0.9314840880697907,-1.3949190573747474,1.2217416615359413,-0.4522520658646618,-0.24272017828745532,0.7017558262776622,1.3683838826407642,-0.6638702399151422,1.0742634875654984
| 3,425
|
Impaired proprioception
| 17
| 43
| 2.422911
| 0.015397
|
O14773,Q9Y619,P00846,Q15120,P54802,P10809,Q12768,P41440,O43819,O00165,Q9NR77,Q8IV08,Q9H0B6,O00400,Q06787,P07196,Q9NQ11
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
620,234,38,199,480,15,174,573,516,582,544,151,543,235,370,188,31
|
582,235,620,746,2576,516,777,2332,1492,38,2016,188,15,1548,2758,2074,1918,2588,573,480,2500,2256,3388,1833,370,174,1150,199,1733,151,1043,2460,2774,1004,682,2369,543,738,31,544,2228,234,2623
|
0.6265756372169713,1.3440006150915877,0.576325735394843,0.45023919311681804,-0.5577941570157251,0.72676448575094,0.42494165677844037,-0.42594849699032294,-0.009373375282462895,3.298795814228332,-0.26880087001046804,1.5384393090995059,4.726233902247758,-0.035180219401076525,-0.6638702399151422,-0.2949128537598711,-0.2166706010189041,-0.5577941570157251,0.6516615278677587,0.776705446342711,-0.5049571593465545,-0.3734383603785469,-1.9269323014404063,-0.16466408850858408,0.9754688945658373,1.5868278002986016,0.170454792757679,1.4899631123019665,-0.11277994734734909,1.7314744805213913,0.2470934090651916,-0.4785882223380154,-0.6638702399151422,0.2725833089167855,0.5259708094615214,-0.42594849699032294,0.7017558262776622,0.4755098070522078,3.5485562599914546,0.7017558262776622,-0.3472314167626071,1.3683838826407642,-0.5577941570157251
| 3,425
|
Regulation of cysteine type endopeptidase activity
| 10
| 53
| 2.422779
| 0.015402
|
Q6IC98,O95831,P31749,P10809,Q15392,Q96K76,Q9BXK5,Q9NR28,Q96F07,O14737
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
129,3,69,15,78,55,284,224,255,157
|
2519,1485,157,3233,853,3031,2788,3,2016,1646,15,1913,3003,1178,2443,2584,69,2795,1717,308,2591,1658,2256,967,1827,3271,3136,481,524,1928,2917,1449,1569,78,1836,2732,129,796,615,255,55,3213,2990,1123,284,2220,224,2570,1479,2426,2826,446,922
|
-0.5313590718804885,-0.009373375282462895,1.683344653281223,-1.1209668411577562,0.37426526772845303,-0.8776773707245988,-0.6904742194938005,6.014053113653133,-0.26880087001046804,-0.08688334071096061,4.726233902247758,-0.2166706010189041,-0.8508280371004248,0.14485178548258162,-0.4785882223380154,-0.5577941570157251,2.4904786675716095,-0.6904742194938005,-0.11277994734734909,1.098902204500058,-0.5577941570157251,-0.08688334071096061,-0.3734383603785469,0.29804530062961365,-0.16466408850858408,-1.2027404258895786,-0.9854364187655524,0.776705446342711,0.72676448575094,-0.2166706010189041,-0.7704934153422345,0.01640387475979311,-0.035180219401076525,2.3026146253507402,-0.16466408850858408,-0.6373004507569276,1.9231530513553758,0.42494165677844037,0.6014637492767998,1.2707141738685634,2.8857686722684996,-1.0666420944020525,-0.8240144161249287,0.1960292991597587,1.1726762745538093,-0.3472314167626071,1.3927445446390339,-0.5313590718804885,0.01640387475979311,-0.4522520658646618,-0.6904742194938005,0.8514278226896782,0.3488861372872074
| 3,425
|
Regulation of cell activation
| 12
| 70
| 2.421755
| 0.015446
|
P30511,P31749,P14174,Q5RKV6,Q9BXW9,Q15046,O96005,P00813,P10809,P60033,P12956,P30825
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
34,69,71,200,102,107,265,14,15,272,17,209
|
2575,1427,883,1908,1699,930,265,2281,2015,14,1494,814,1227,1812,1646,1141,1968,15,2978,17,71,988,1178,34,209,69,609,1917,2638,1027,936,859,2981,1608,861,272,825,1505,1398,3208,3391,3336,1184,1884,2260,107,1836,2362,200,3045,1889,904,2928,2739,1894,1943,633,1259,2266,487,950,1366,1367,767,102,3174,1584,2374,327,2714
|
-0.5577941570157251,0.01640387475979311,0.3488861372872074,-0.2166706010189041,-0.11277994734734909,0.32347952895027443,1.2217416615359413,-0.3996773248018237,-0.26880087001046804,4.748071870065068,-0.009373375282462895,0.39961706105910194,0.11922012561949845,-0.16466408850858408,-0.08688334071096061,0.170454792757679,-0.24272017828745532,4.726233902247758,-0.8240144161249287,4.441103682259946,2.467061710936354,0.2725833089167855,0.14485178548258162,3.412565525129457,1.4413984485653908,2.4904786675716095,0.6014637492767998,-0.2166706010189041,-0.5842626139461844,0.2470934090651916,0.32347952895027443,0.37426526772845303,-0.8240144161249287,-0.0610168199068948,0.37426526772845303,1.1972206297942891,0.39961706105910194,-0.009373375282462895,0.0421516914587663,-1.0666420944020525,-1.9838794806387696,-1.42253413815144,0.14485178548258162,-0.1906519624283154,-0.3734383603785469,2.089793763639897,-0.16466408850858408,-0.42594849699032294,1.4899631123019665,-0.8776773707245988,-0.1906519624283154,0.3488861372872074,-0.7704934153422345,-0.6373004507569276,-0.1906519624283154,-0.2166706010189041,0.576325735394843,0.11922012561949845,-0.3734383603785469,0.776705446342711,0.32347952895027443,0.06787023399176167,0.06787023399176167,0.45023919311681804,2.1372248000072944,-1.012467779172713,-0.035180219401076525,-0.42594849699032294,1.0742634875654984,-0.6107646440167533
| 3,425
|
Organic acid transmembrane transport
| 13
| 32
| 2.407238
| 0.016074
|
P33527,Q9Y619,P53985,P31749,P08183,O43772,P41440,P23786,Q9H2D1,P30825,Q9UJS0,Q9BQT8,P31751
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
219,234,411,69,138,10,573,149,472,209,547,94,95
|
10,583,1706,2788,2386,138,2387,932,149,1915,209,69,95,2187,219,573,1823,2840,411,2353,1569,1457,3021,1992,2304,94,472,3262,3105,2001,547,234
|
5.009094029804443,0.6265756372169713,-0.11277994734734909,-0.6904742194938005,-0.4522520658646618,1.827480517995054,-0.4522520658646618,0.32347952895027443,1.7555075594715182,-0.2166706010189041,1.4413984485653908,2.4904786675716095,2.1845767415122475,-0.3472314167626071,1.3927445446390339,0.6516615278677587,-0.16466408850858408,-0.7171125997850363,0.9011180973452062,-0.42594849699032294,-0.035180219401076525,0.01640387475979311,-0.8508280371004248,-0.24272017828745532,-0.3996773248018237,2.2082232468714693,0.8016379926908211,-1.175444027337681,-0.9314840880697907,-0.24272017828745532,0.7017558262776622,1.3683838826407642
| 3,425
|
Horizontal nystagmus
| 6
| 26
| 2.40172
| 0.016318
|
P07602,O95831,P00846,Q9NP73,Q9H061,Q9NQ11
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
251,3,38,269,146,31
|
2575,745,620,2576,1592,2332,3,38,2489,251,2074,1236,1720,2500,2727,1985,1200,2774,2888,146,269,31,2569,352,2426,2228
|
-0.5577941570157251,0.45023919311681804,0.576325735394843,-0.5577941570157251,-0.0610168199068948,-0.42594849699032294,6.014053113653133,3.298795814228332,-0.5049571593465545,1.2707141738685634,-0.2949128537598711,0.11922012561949845,-0.11277994734734909,-0.5049571593465545,-0.6373004507569276,-0.24272017828745532,0.14485178548258162,-0.6638702399151422,-0.7437855934072211,1.7795195335651102,1.2217416615359413,3.5485562599914546,-0.5313590718804885,1.0249143581417541,-0.4522520658646618,-0.3472314167626071
| 3,425
|
Cell activation involved in immune response
| 7
| 41
| 2.399895
| 0.0164
|
P30511,Q5RKV6,Q15046,P05067,P00813,P10809,Q9UQ84
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
34,200,107,266,14,15,156
|
3059,2863,1699,1961,930,2281,14,1494,814,2976,266,1646,1141,15,2978,2244,34,671,819,936,1608,1345,272,1830,826,3336,1184,107,200,3045,1889,904,1047,2266,487,1367,654,1584,2374,1132,156
|
-0.9045626443840719,-0.7437855934072211,-0.11277994734734909,-0.24272017828745532,0.32347952895027443,-0.3996773248018237,4.748071870065068,-0.009373375282462895,0.39961706105910194,-0.8240144161249287,1.2217416615359413,-0.08688334071096061,0.170454792757679,4.726233902247758,-0.8240144161249287,-0.3734383603785469,3.412565525129457,0.5259708094615214,0.39961706105910194,0.32347952895027443,-0.0610168199068948,0.06787023399176167,1.1972206297942891,-0.16466408850858408,0.39961706105910194,-1.42253413815144,0.14485178548258162,2.089793763639897,1.4899631123019665,-0.8776773707245988,-0.1906519624283154,0.3488861372872074,0.2470934090651916,-0.3734383603785469,0.776705446342711,0.06787023399176167,0.551161465774754,-0.035180219401076525,-0.42594849699032294,0.1960292991597587,1.7074202081888503
| 3,425
|
Initiation factor
| 17
| 36
| 2.394548
| 0.016641
|
Q15056,Q9NR50,Q9Y262,P05198,Q7Z478,P55010,O43583,O75822,O00303,P60228,Q14240,P49770,Q9ULC4,P23588,O60841,Q9UI10,O15372
|
Functions
|
Protein Atlas Molecular function
|
protein_atlas_molecular_function
|
868,365,495,857,832,45,552,333,115,893,239,467,424,307,775,644,748
|
115,1865,748,552,1223,775,1383,333,857,1228,1497,307,2445,1502,467,45,2086,2350,893,940,1395,1446,1185,2204,997,1401,239,868,1464,832,1800,365,2376,644,424,495
|
2.0184975203635163,-0.1906519624283154,0.45023919311681804,0.676721548752089,0.11922012561949845,0.42494165677844037,0.0421516914587663,1.0496009088870837,0.37426526772845303,0.11922012561949845,-0.009373375282462895,1.098902204500058,-0.4785882223380154,-0.009373375282462895,0.8016379926908211,3.070015851916738,-0.2949128537598711,-0.42594849699032294,0.3488861372872074,0.32347952895027443,0.0421516914587663,0.01640387475979311,0.14485178548258162,-0.3472314167626071,0.2725833089167855,0.0421516914587663,1.3440006150915877,0.37426526772845303,0.01640387475979311,0.39961706105910194,-0.1387068069964346,1.0002037240901964,-0.42594849699032294,0.576325735394843,0.9011180973452062,0.776705446342711
| 3,425
|
Translation factor
| 6
| 27
| 2.38798
| 0.016941
|
O75153,Q9Y262,P29692,P55010,O75822,P23588
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
66,495,7,45,333,307
|
1865,1223,66,333,857,1228,1497,307,1499,7,3205,45,2086,2350,893,2026,1349,1395,1446,2204,997,555,868,1407,1001,1753,495
|
-0.1906519624283154,0.11922012561949845,2.5606178833025024,1.0496009088870837,0.37426526772845303,0.11922012561949845,-0.009373375282462895,1.098902204500058,-0.009373375282462895,5.4400213336505425,-1.0666420944020525,3.070015851916738,-0.2949128537598711,-0.42594849699032294,0.3488861372872074,-0.26880087001046804,0.06787023399176167,0.0421516914587663,0.01640387475979311,-0.3472314167626071,0.2725833089167855,0.676721548752089,0.37426526772845303,0.0421516914587663,0.2725833089167855,-0.11277994734734909,0.776705446342711
| 3,425
|
Intracellular calcium-sensing protein
| 6
| 15
| 2.38736
| 0.01697
|
P80303,O43852,Q14257,Q02818,Q8N163,P41208
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
32,160,36,134,18,158
|
160,1872,158,2728,32,134,36,2151,2811,2658,592,18,654,3076,283
|
1.6592477259317628,-0.1906519624283154,1.683344653281223,-0.6373004507569276,3.480632910343951,1.851429702113107,3.3443526398316665,-0.3210563089295906,-0.6904742194938005,-0.5842626139461844,0.6265756372169713,4.441103682259946,0.551161465774754,-0.9045626443840719,1.1726762745538093
| 3,425
|
Calmodulin
| 6
| 15
| 2.38736
| 0.01697
|
P80303,O43852,Q14257,Q02818,Q8N163,P41208
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
32,160,36,134,18,158
|
160,1872,158,2728,32,134,36,2151,2811,2658,592,18,654,3076,283
|
1.6592477259317628,-0.1906519624283154,1.683344653281223,-0.6373004507569276,3.480632910343951,1.851429702113107,3.3443526398316665,-0.3210563089295906,-0.6904742194938005,-0.5842626139461844,0.6265756372169713,4.441103682259946,0.551161465774754,-0.9045626443840719,1.1726762745538093
| 3,425
|
Sensorimotor neuropathy
| 7
| 32
| 2.38242
| 0.017199
|
P07602,O95831,P00846,Q15120,P05023,P03886,P07196
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
251,3,38,199,41,27,188
|
745,2064,1592,3,1386,38,27,690,41,188,251,1548,1437,1918,2535,573,2193,2912,2256,3291,725,1150,199,941,3072,486,2935,544,2569,2426,329,1060
|
0.45023919311681804,-0.2949128537598711,-0.0610168199068948,6.014053113653133,0.0421516914587663,3.298795814228332,3.8860619373950085,0.5007536343265028,3.1617288490354225,1.5384393090995059,1.2707141738685634,-0.035180219401076525,0.01640387475979311,-0.2166706010189041,-0.5313590718804885,0.6516615278677587,-0.3472314167626071,-0.7704934153422345,-0.3734383603785469,-1.2574501425253701,0.4755098070522078,0.170454792757679,1.4899631123019665,0.32347952895027443,-0.9045626443840719,0.776705446342711,-0.7704934153422345,0.7017558262776622,-0.5313590718804885,-0.4522520658646618,1.0742634875654984,0.2470934090651916
| 3,425
|
Iron ion binding
| 6
| 25
| 2.381739
| 0.017231
|
P22830,Q9BV57,P31350,Q15800,Q9BU89,Q16850
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
1,178,173,240,51,23
|
2974,2325,885,2752,2065,781,1,2760,173,863,1833,240,23,336,760,1621,510,1039,3124,51,178,2167,3192,1163,800
|
-0.8240144161249287,-0.42594849699032294,0.3488861372872074,-0.6638702399151422,-0.2949128537598711,0.42494165677844037,6.931947993482619,-0.6638702399151422,1.5868278002986016,0.37426526772845303,-0.16466408850858408,1.3440006150915877,4.109169389067719,1.0496009088870837,0.45023919311681804,-0.0610168199068948,0.7517476513909233,0.2470934090651916,-0.9584419344202308,2.931934335739412,1.5868278002986016,-0.3210563089295906,-1.0395362564915789,0.170454792757679,0.42494165677844037
| 3,425
|
Apc c mediated degradation of cell cycle proteins
| 15
| 55
| 2.379608
| 0.017331
|
P28070,Q14997,Q06323,P28072,Q99436,Q9UL46,P49721,P28074,Q96DE5,P20618,O60566,O00231,P25787,P61289,O00487
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
289,414,291,194,232,294,103,139,204,270,395,88,57,506,304
|
88,2670,304,2234,1279,1543,2628,395,1643,648,2137,1176,270,1067,2759,57,1710,2722,1816,289,194,139,2077,2346,1922,1605,1876,103,1824,2982,2025,1104,506,1722,1503,2876,1107,291,3394,1565,2808,2203,1188,414,1454,733,204,232,1415,1083,1420,714,548,294,1692
|
2.2318502116319068,-0.6107646440167533,1.098902204500058,-0.3734383603785469,0.0935596600019327,-0.035180219401076525,-0.5842626139461844,0.9259261957288346,-0.08688334071096061,0.551161465774754,-0.3210563089295906,0.14485178548258162,1.1972206297942891,0.2215754549719998,-0.6638702399151422,2.8163886227017083,-0.11277994734734909,-0.6373004507569276,-0.16466408850858408,1.1481084899134386,1.5142122212082996,1.827480517995054,-0.2949128537598711,-0.42594849699032294,-0.2166706010189041,-0.0610168199068948,-0.1906519624283154,2.113519207995092,-0.16466408850858408,-0.8240144161249287,-0.26880087001046804,0.1960292991597587,0.7517476513909233,-0.11277994734734909,-0.009373375282462895,-0.7437855934072211,0.1960292991597587,1.1481084899134386,-2.0410176675364773,-0.035180219401076525,-0.6904742194938005,-0.3472314167626071,0.14485178548258162,0.9011180973452062,0.01640387475979311,0.4755098070522078,1.4656918868469564,1.3683838826407642,0.0421516914587663,0.2215754549719998,0.0421516914587663,0.5007536343265028,0.7017558262776622,1.1481084899134386,-0.08688334071096061
| 3,425
|
Lipid transport
| 6
| 24
| 2.377476
| 0.017432
|
Q9BZF3,O15118,Q99720,Q9P260,Q9H4L5,Q9BQE5
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
4,380,20,379,185,30
|
1425,2625,380,3300,2532,2285,3066,1975,444,2411,1301,636,20,30,1264,2111,1799,2051,4,185,1858,379,687,1061
|
0.01640387475979311,-0.5842626139461844,0.950709756463659,-1.2848639936597672,-0.5313590718804885,-0.3996773248018237,-0.9045626443840719,-0.24272017828745532,0.8514278226896782,-0.4522520658646618,0.0935596600019327,0.576325735394843,4.374972711166257,3.6163370124132777,0.11922012561949845,-0.2949128537598711,-0.1387068069964346,-0.26880087001046804,5.950692891080032,1.5626444707730802,-0.16466408850858408,0.9754688945658373,0.5259708094615214,0.2470934090651916
| 3,425
|
Duplication involving bones of the feet
| 7
| 25
| 2.357894
| 0.018379
|
Q8NCM8,Q96J42,Q2M1P5,Q15125,O43924,Q10713,O75665
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
133,140,299,46,82,346,150
|
1426,82,150,2065,428,1493,2281,2341,2250,2348,346,2597,675,46,299,1844,133,1794,2741,140,2422,1951,771,2003,1536
|
0.01640387475979311,2.255457712363717,1.7314744805213913,-0.2949128537598711,0.876285345323554,-0.009373375282462895,-0.3996773248018237,-0.42594849699032294,-0.3734383603785469,-0.42594849699032294,1.0249143581417541,-0.5577941570157251,0.5259708094615214,3.047045185687798,1.1235171691084074,-0.16466408850858408,1.875358128951854,-0.1387068069964346,-0.6373004507569276,1.827480517995054,-0.4522520658646618,-0.2166706010189041,0.45023919311681804,-0.24272017828745532,-0.009373375282462895
| 3,425
|
Mitotic g1 phase and g1 s transition
| 18
| 79
| 2.35409
| 0.018568
|
P28070,P28072,Q9Y619,Q06323,Q99436,P31749,P49721,Q9NR33,Q9UL46,P28074,P20618,P31350,Q14566,P33991,O00231,P25787,P00374,P31751
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
289,194,234,291,232,69,103,169,294,139,270,173,310,184,88,57,63,95
|
88,2670,304,2234,1543,3060,2865,1643,63,1765,584,648,1230,3249,888,1596,2137,816,1176,270,1067,520,2759,57,1710,2722,1604,1816,289,194,139,1144,466,173,69,95,184,1651,670,2679,2346,2496,1922,1605,1657,1554,1876,103,966,1824,2025,2502,1104,506,1722,1503,2876,1831,1107,3038,291,626,2808,2203,3117,1188,310,1454,2297,1892,733,232,1415,169,1687,3054,294,1692,234
|
2.2318502116319068,-0.6107646440167533,1.098902204500058,-0.3734383603785469,-0.035180219401076525,-0.9045626443840719,-0.7437855934072211,-0.08688334071096061,2.677148568313713,-0.1387068069964346,0.6265756372169713,0.551161465774754,0.11922012561949845,-1.1481862519519852,0.3488861372872074,-0.0610168199068948,-0.3210563089295906,0.39961706105910194,0.14485178548258162,1.1972206297942891,0.2215754549719998,0.72676448575094,-0.6638702399151422,2.8163886227017083,-0.11277994734734909,-0.6373004507569276,-0.0610168199068948,-0.16466408850858408,1.1481084899134386,1.5142122212082996,1.827480517995054,0.170454792757679,0.8016379926908211,1.5868278002986016,2.4904786675716095,2.1845767415122475,1.5626444707730802,-0.08688334071096061,0.5259708094615214,-0.6107646440167533,-0.42594849699032294,-0.5049571593465545,-0.2166706010189041,-0.0610168199068948,-0.08688334071096061,-0.035180219401076525,-0.1906519624283154,2.113519207995092,0.29804530062961365,-0.16466408850858408,-0.26880087001046804,-0.5049571593465545,0.1960292991597587,0.7517476513909233,-0.11277994734734909,-0.009373375282462895,-0.7437855934072211,-0.16466408850858408,0.1960292991597587,-0.8776773707245988,1.1481084899134386,0.576325735394843,-0.6904742194938005,-0.3472314167626071,-0.9584419344202308,0.14485178548258162,1.098902204500058,0.01640387475979311,-0.3996773248018237,-0.1906519624283154,0.4755098070522078,1.3683838826407642,0.0421516914587663,1.6351293355923024,-0.08688334071096061,-0.8776773707245988,1.1481084899134386,-0.08688334071096061,1.3683838826407642
| 3,425
|
Proteasome complex
| 10
| 48
| 2.342682
| 0.019146
|
P28070,P28072,Q06323,Q99436,Q9UL46,P49721,P28074,P20618,O00231,P25787
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
289,194,291,232,294,103,139,270,88,57
|
88,2670,304,2234,1543,986,1643,3179,1176,270,2759,57,1710,2722,1816,289,194,139,2346,1922,1605,1876,103,1824,1239,785,2025,2256,1104,506,1722,1503,2876,2091,291,2808,414,1454,2097,2809,1787,2657,733,232,1415,294,1692,2321
|
2.2318502116319068,-0.6107646440167533,1.098902204500058,-0.3734383603785469,-0.035180219401076525,0.2725833089167855,-0.08688334071096061,-1.0395362564915789,0.14485178548258162,1.1972206297942891,-0.6638702399151422,2.8163886227017083,-0.11277994734734909,-0.6373004507569276,-0.16466408850858408,1.1481084899134386,1.5142122212082996,1.827480517995054,-0.42594849699032294,-0.2166706010189041,-0.0610168199068948,-0.1906519624283154,2.113519207995092,-0.16466408850858408,0.11922012561949845,0.42494165677844037,-0.26880087001046804,-0.3734383603785469,0.1960292991597587,0.7517476513909233,-0.11277994734734909,-0.009373375282462895,-0.7437855934072211,-0.2949128537598711,1.1481084899134386,-0.6904742194938005,0.9011180973452062,0.01640387475979311,-0.2949128537598711,-0.6904742194938005,-0.1387068069964346,-0.5842626139461844,0.4755098070522078,1.3683838826407642,0.0421516914587663,1.1481084899134386,-0.08688334071096061,-0.3996773248018237
| 3,425
|
Disproportionate short limb short stature
| 14
| 22
| 2.339692
| 0.0193
|
Q14739,Q13426,Q8NCM8,Q14696,Q32P28,Q15125,Q9UBM7,Q15392,P42345,Q7LGA3,Q9Y366,O15228,Q03164,O75718
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
675,413,133,727,336,46,771,78,819,275,52,773,345,778
|
1541,773,3032,778,1968,3278,819,1552,345,413,727,675,46,78,336,1358,275,133,874,2741,771,52
|
-0.035180219401076525,0.42494165677844037,-0.8776773707245988,0.42494165677844037,-0.24272017828745532,-1.2300757093182833,0.39961706105910194,-0.035180219401076525,1.0249143581417541,0.9011180973452062,0.4755098070522078,0.5259708094615214,3.047045185687798,2.3026146253507402,1.0496009088870837,0.06787023399176167,1.1972206297942891,1.875358128951854,0.37426526772845303,-0.6373004507569276,0.45023919311681804,2.931934335739412
| 3,425
|
Ventricular arrhythmia
| 9
| 40
| 2.339546
| 0.019307
|
P00846,O43772,P09493,P23786,Q9HD47,P50336,Q01130,P42892,P03886
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
38,10,106,149,277,309,211,25,27
|
10,1962,2280,1386,38,1339,27,690,2389,106,3002,1814,3390,2392,1390,2531,1971,149,2081,2980,1714,25,320,452,309,860,211,2290,1562,996,2690,2460,833,1203,3261,682,2854,3051,277,2895
|
5.009094029804443,-0.24272017828745532,-0.3996773248018237,0.0421516914587663,3.298795814228332,0.06787023399176167,3.8860619373950085,0.5007536343265028,-0.4522520658646618,2.089793763639897,-0.8508280371004248,-0.16466408850858408,-1.9838794806387696,-0.4522520658646618,0.0421516914587663,-0.5313590718804885,-0.24272017828745532,1.7555075594715182,-0.2949128537598711,-0.8240144161249287,-0.11277994734734909,3.9531504082961226,1.0742634875654984,0.8265454114723118,1.098902204500058,0.37426526772845303,1.4413984485653908,-0.3996773248018237,-0.035180219401076525,0.2725833089167855,-0.6107646440167533,-0.4785882223380154,0.39961706105910194,0.14485178548258162,-1.175444027337681,0.5259708094615214,-0.7171125997850363,-0.8776773707245988,1.1972206297942891,-0.7437855934072211
| 3,425
|
Endopeptidase activity
| 17
| 65
| 2.338397
| 0.019367
|
Q9BYT8,P22695,P28070,P28072,Q9BXS4,Q99436,P49721,Q4J6C6,P28074,P20618,Q96RU2,Q13043,Q2T9J0,Q10713,Q96K76,P42892,Q92643
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
389,288,289,194,197,232,103,43,139,270,92,273,274,346,55,25,387
|
620,1062,853,394,2753,566,2526,1341,1388,2246,270,288,2722,289,194,139,2833,2949,1920,3220,1027,25,2589,650,1876,103,1825,861,1239,1556,1104,722,346,273,1567,2647,1981,274,43,509,1192,2454,3046,1792,3371,1893,387,949,1364,1204,55,92,2047,232,2990,877,2890,197,389,2564,881,604,1134,2432,1060
|
0.576325735394843,0.2215754549719998,0.37426526772845303,0.9259261957288346,-0.6638702399151422,0.6516615278677587,-0.5313590718804885,0.06787023399176167,0.0421516914587663,-0.3734383603785469,1.1972206297942891,1.1481084899134386,-0.6373004507569276,1.1481084899134386,1.5142122212082996,1.827480517995054,-0.7171125997850363,-0.7972362829735179,-0.2166706010189041,-1.093785539462249,0.2470934090651916,3.9531504082961226,-0.5577941570157251,0.551161465774754,-0.1906519624283154,2.113519207995092,-0.16466408850858408,0.37426526772845303,0.11922012561949845,-0.035180219401076525,0.1960292991597587,0.4755098070522078,1.0249143581417541,1.1972206297942891,-0.035180219401076525,-0.5842626139461844,-0.24272017828745532,1.1972206297942891,3.1617288490354225,0.7517476513909233,0.14485178548258162,-0.4785882223380154,-0.8776773707245988,-0.1387068069964346,-1.5890980607614524,-0.1906519624283154,0.950709756463659,0.32347952895027443,0.06787023399176167,0.14485178548258162,2.8857686722684996,2.2318502116319068,-0.26880087001046804,1.3683838826407642,-0.8240144161249287,0.37426526772845303,-0.7437855934072211,1.5142122212082996,0.950709756463659,-0.5313590718804885,0.37426526772845303,0.6265756372169713,0.1960292991597587,-0.4522520658646618,0.2470934090651916
| 3,425
|
Regulation of mrna stability by proteins that bind au rich elements
| 23
| 67
| 2.338244
| 0.019375
|
Q13868,P28074,P20618,Q9NPI6,P28070,Q14997,Q06323,Q9UL46,P25787,Q16539,Q9Y3B2,O00487,Q92973,P28072,P31749,Q5RKV6,Q14103,Q9NQT4,O00231,Q99436,P49721,Q01105,P61289
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
628,139,270,684,289,414,291,294,57,575,716,304,458,194,69,200,700,474,88,232,103,104,506
|
88,2670,304,2234,1280,1543,1643,2131,3179,2527,1231,988,1176,270,2759,57,1710,2722,1816,289,194,139,69,1235,2080,2346,965,1922,1605,1876,103,1824,2025,1104,506,1722,1503,2876,1291,104,1446,1398,1507,291,2808,628,700,414,1454,3163,2294,575,200,733,834,458,3049,232,1415,3052,684,474,1584,294,1692,2122,716
|
2.2318502116319068,-0.6107646440167533,1.098902204500058,-0.3734383603785469,0.0935596600019327,-0.035180219401076525,-0.08688334071096061,-0.3210563089295906,-1.0395362564915789,-0.5313590718804885,0.11922012561949845,0.2725833089167855,0.14485178548258162,1.1972206297942891,-0.6638702399151422,2.8163886227017083,-0.11277994734734909,-0.6373004507569276,-0.16466408850858408,1.1481084899134386,1.5142122212082996,1.827480517995054,2.4904786675716095,0.11922012561949845,-0.2949128537598711,-0.42594849699032294,0.29804530062961365,-0.2166706010189041,-0.0610168199068948,-0.1906519624283154,2.113519207995092,-0.16466408850858408,-0.26880087001046804,0.1960292991597587,0.7517476513909233,-0.11277994734734909,-0.009373375282462895,-0.7437855934072211,0.0935596600019327,2.113519207995092,0.01640387475979311,0.0421516914587663,-0.009373375282462895,1.1481084899134386,-0.6904742194938005,0.576325735394843,0.5007536343265028,0.9011180973452062,0.01640387475979311,-1.012467779172713,-0.3996773248018237,0.6516615278677587,1.4899631123019665,0.4755098070522078,0.39961706105910194,0.8265454114723118,-0.8776773707245988,1.3683838826407642,0.0421516914587663,-0.8776773707245988,0.5259708094615214,0.8016379926908211,-0.035180219401076525,1.1481084899134386,-0.08688334071096061,-0.2949128537598711,0.5007536343265028
| 3,425
|
Peripheral axonal neuropathy
| 8
| 60
| 2.329419
| 0.019837
|
P07602,O95831,P00846,Q15046,Q8IV08,P03886,P07196,Q9NQ11
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
251,3,38,107,151,27,188,31
|
2323,882,2064,1701,1592,1335,1909,1492,3,1386,38,27,690,3179,188,2526,251,2389,1966,1814,2758,571,1972,1393,671,2023,1718,344,2500,2256,1877,1833,2449,725,508,413,1036,107,791,1114,2769,1733,2264,151,2041,975,2460,1573,1004,682,3076,953,543,268,31,2824,1528,2426,1060,2623
|
-0.42594849699032294,0.3488861372872074,-0.2949128537598711,-0.11277994734734909,-0.0610168199068948,0.06787023399176167,-0.2166706010189041,-0.009373375282462895,6.014053113653133,0.0421516914587663,3.298795814228332,3.8860619373950085,0.5007536343265028,-1.0395362564915789,1.5384393090995059,-0.5313590718804885,1.2707141738685634,-0.4522520658646618,-0.24272017828745532,-0.16466408850858408,-0.6638702399151422,0.6516615278677587,-0.24272017828745532,0.0421516914587663,0.5259708094615214,-0.26880087001046804,-0.11277994734734909,1.0249143581417541,-0.5049571593465545,-0.3734383603785469,-0.1906519624283154,-0.16466408850858408,-0.4785882223380154,0.4755098070522078,0.7517476513909233,0.9011180973452062,0.2470934090651916,2.089793763639897,0.42494165677844037,0.1960292991597587,-0.6638702399151422,-0.11277994734734909,-0.3734383603785469,1.7314744805213913,-0.26880087001046804,0.29804530062961365,-0.4785882223380154,-0.035180219401076525,0.2725833089167855,0.5259708094615214,-0.9045626443840719,0.32347952895027443,0.7017558262776622,1.2217416615359413,3.5485562599914546,-0.6904742194938005,-0.009373375282462895,-0.4522520658646618,0.2470934090651916,-0.5577941570157251
| 3,425
|
Intrinsic component of mitochondrial inner membrane
| 11
| 36
| 2.320925
| 0.020291
|
Q9Y2R0,Q9NX63,Q8N8Q8,O60830,Q99595,Q53H12,Q9HC21,O43819,Q13505,P50336,Q9NWR8
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
329,492,292,5,8,453,268,516,84,309,491
|
1486,516,5,2904,1021,3290,309,2916,84,1835,1728,900,453,901,1730,1790,1463,292,2813,578,1302,1992,8,2111,2822,2424,3105,1523,268,1214,491,492,2474,329,1060,1378
|
-0.009373375282462895,0.72676448575094,5.738741189752724,-0.7704934153422345,0.2470934090651916,-1.2574501425253701,1.098902204500058,-0.7704934153422345,2.255457712363717,-0.16466408850858408,-0.11277994734734909,0.3488861372872074,0.8265454114723118,0.3488861372872074,-0.11277994734734909,-0.1387068069964346,0.01640387475979311,1.1481084899134386,-0.6904742194938005,0.6516615278677587,0.0935596600019327,-0.24272017828745532,5.160492534890691,-0.2949128537598711,-0.6904742194938005,-0.4522520658646618,-0.9314840880697907,-0.009373375282462895,1.2217416615359413,0.14485178548258162,0.776705446342711,0.776705446342711,-0.4785882223380154,1.0742634875654984,0.2470934090651916,0.06787023399176167
| 3,425
|
Neuron death
| 13
| 78
| 2.290079
| 0.022017
|
Q4ZIN3,P30511,O95831,P31749,Q01105,P50897,Q9UMX5,Q15392,Q99720,P07196,Q9NR28,P31751,Q9NQ11
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
96,34,3,69,104,203,207,78,20,188,224,95,31
|
1382,853,665,987,2788,1909,3,2489,2943,3152,2976,266,857,2016,188,2018,2134,1141,691,1870,2246,34,69,95,2795,1917,1027,936,858,503,1717,1718,1285,203,2084,696,1556,1394,1347,3010,1722,1927,3136,524,1725,1928,104,2449,1446,1978,3322,2355,788,2031,995,1112,78,96,1298,1893,2853,615,418,838,3213,2990,20,2271,31,879,224,847,1860,848,207,1132,3131,719
|
0.0421516914587663,0.37426526772845303,0.5259708094615214,0.2725833089167855,-0.6904742194938005,-0.2166706010189041,6.014053113653133,-0.5049571593465545,-0.7972362829735179,-1.012467779172713,-0.8240144161249287,1.2217416615359413,0.37426526772845303,-0.26880087001046804,1.5384393090995059,-0.26880087001046804,-0.3210563089295906,0.170454792757679,0.5007536343265028,-0.1906519624283154,-0.3734383603785469,3.412565525129457,2.4904786675716095,2.1845767415122475,-0.6904742194938005,-0.2166706010189041,0.2470934090651916,0.32347952895027443,0.37426526772845303,0.7517476513909233,-0.11277994734734909,-0.11277994734734909,0.0935596600019327,1.4656918868469564,-0.2949128537598711,0.5007536343265028,-0.035180219401076525,0.0421516914587663,0.06787023399176167,-0.8508280371004248,-0.11277994734734909,-0.2166706010189041,-0.9854364187655524,0.72676448575094,-0.11277994734734909,-0.2166706010189041,2.113519207995092,-0.4785882223380154,0.01640387475979311,-0.24272017828745532,-1.367344786047239,-0.42594849699032294,0.42494165677844037,-0.26880087001046804,0.2725833089167855,0.1960292991597587,2.3026146253507402,2.1845767415122475,0.0935596600019327,-0.1906519624283154,-0.7171125997850363,0.6014637492767998,0.9011180973452062,0.39961706105910194,-1.0666420944020525,-0.8240144161249287,4.374972711166257,-0.3734383603785469,3.5485562599914546,0.37426526772845303,1.3927445446390339,0.39961706105910194,-0.16466408850858408,0.39961706105910194,1.4656918868469564,0.1960292991597587,-0.9584419344202308,0.5007536343265028
| 3,425
|
Defective cftr causes cystic fibrosis
| 11
| 43
| 2.28696
| 0.022198
|
P28070,P28072,Q06323,Q99436,Q9UL46,P49721,P28074,P20618,O00231,P25787,O00487
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
289,194,291,232,294,103,139,270,88,57,304
|
88,2670,304,2234,1543,621,1643,2332,1176,270,2759,57,1710,2722,1816,289,194,139,2346,1922,1605,1876,103,1824,2025,2256,1104,506,1722,1503,2876,291,2808,414,1454,733,232,1415,3348,878,916,294,1692
|
2.2318502116319068,-0.6107646440167533,1.098902204500058,-0.3734383603785469,-0.035180219401076525,0.576325735394843,-0.08688334071096061,-0.42594849699032294,0.14485178548258162,1.1972206297942891,-0.6638702399151422,2.8163886227017083,-0.11277994734734909,-0.6373004507569276,-0.16466408850858408,1.1481084899134386,1.5142122212082996,1.827480517995054,-0.42594849699032294,-0.2166706010189041,-0.0610168199068948,-0.1906519624283154,2.113519207995092,-0.16466408850858408,-0.26880087001046804,-0.3734383603785469,0.1960292991597587,0.7517476513909233,-0.11277994734734909,-0.009373375282462895,-0.7437855934072211,1.1481084899134386,-0.6904742194938005,0.9011180973452062,0.01640387475979311,0.4755098070522078,1.3683838826407642,0.0421516914587663,-1.4501903172702728,0.37426526772845303,0.3488861372872074,1.1481084899134386,-0.08688334071096061
| 3,425
|
Disproportionate short stature
| 15
| 26
| 2.283714
| 0.022388
|
Q14739,Q13426,Q8NCM8,Q14696,Q32P28,Q15125,Q9UBM7,P16278,Q15392,Q7LGA3,Q9Y366,P42345,O15228,Q03164,O75718
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
675,413,133,727,336,46,771,519,78,275,52,819,773,345,778
|
1541,773,3032,778,1968,519,3278,819,1552,345,413,727,675,2096,46,78,336,1358,275,133,874,2741,2046,771,1633,52
|
-0.035180219401076525,0.42494165677844037,-0.8776773707245988,0.42494165677844037,-0.24272017828745532,0.72676448575094,-1.2300757093182833,0.39961706105910194,-0.035180219401076525,1.0249143581417541,0.9011180973452062,0.4755098070522078,0.5259708094615214,-0.2949128537598711,3.047045185687798,2.3026146253507402,1.0496009088870837,0.06787023399176167,1.1972206297942891,1.875358128951854,0.37426526772845303,-0.6373004507569276,-0.26880087001046804,0.45023919311681804,-0.0610168199068948,2.931934335739412
| 3,425
|
Positive regulation of peptidase activity
| 11
| 44
| 2.282719
| 0.022447
|
Q6IC98,O95831,Q06323,Q9UL46,P05067,P10809,Q9BXK5,P49593,Q9NR28,Q96F07,O14737
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
129,3,291,294,266,15,284,308,224,255,157
|
2519,304,1485,157,853,666,3031,2788,3033,3,266,1646,15,1178,671,1717,308,2591,2256,506,1827,3271,3136,1928,291,2917,2031,414,2809,2732,129,1893,796,615,255,2046,2990,1123,284,224,2426,2826,294,922
|
-0.5313590718804885,1.098902204500058,-0.009373375282462895,1.683344653281223,0.37426526772845303,0.5259708094615214,-0.8776773707245988,-0.6904742194938005,-0.8776773707245988,6.014053113653133,1.2217416615359413,-0.08688334071096061,4.726233902247758,0.14485178548258162,0.5259708094615214,-0.11277994734734909,1.098902204500058,-0.5577941570157251,-0.3734383603785469,0.7517476513909233,-0.16466408850858408,-1.2027404258895786,-0.9854364187655524,-0.2166706010189041,1.1481084899134386,-0.7704934153422345,-0.26880087001046804,0.9011180973452062,-0.6904742194938005,-0.6373004507569276,1.9231530513553758,-0.1906519624283154,0.42494165677844037,0.6014637492767998,1.2707141738685634,-0.26880087001046804,-0.8240144161249287,0.1960292991597587,1.1726762745538093,1.3927445446390339,-0.4522520658646618,-0.6904742194938005,1.1481084899134386,0.3488861372872074
| 3,425
|
Abc transporter disorders
| 11
| 44
| 2.269192
| 0.023257
|
P28070,P28072,Q06323,Q99436,Q9UL46,P49721,P28074,P20618,O00231,P25787,O00487
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
289,194,291,232,294,103,139,270,88,57,304
|
88,2670,304,2234,1543,621,1643,2332,1176,270,2759,57,1710,2722,1816,289,194,139,2346,1922,1605,1876,103,1824,2025,2256,1104,506,1722,1503,2876,291,2808,414,1454,733,232,1415,3348,878,2222,916,294,1692
|
2.2318502116319068,-0.6107646440167533,1.098902204500058,-0.3734383603785469,-0.035180219401076525,0.576325735394843,-0.08688334071096061,-0.42594849699032294,0.14485178548258162,1.1972206297942891,-0.6638702399151422,2.8163886227017083,-0.11277994734734909,-0.6373004507569276,-0.16466408850858408,1.1481084899134386,1.5142122212082996,1.827480517995054,-0.42594849699032294,-0.2166706010189041,-0.0610168199068948,-0.1906519624283154,2.113519207995092,-0.16466408850858408,-0.26880087001046804,-0.3734383603785469,0.1960292991597587,0.7517476513909233,-0.11277994734734909,-0.009373375282462895,-0.7437855934072211,1.1481084899134386,-0.6904742194938005,0.9011180973452062,0.01640387475979311,0.4755098070522078,1.3683838826407642,0.0421516914587663,-1.4501903172702728,0.37426526772845303,-0.3472314167626071,0.3488861372872074,1.1481084899134386,-0.08688334071096061
| 3,425
|
Response to ionizing radiation
| 15
| 40
| 2.257517
| 0.023976
|
P50570,O75844,Q13426,P09874,Q9BXW9,P29692,Q9C0C2,Q9H1E3,Q15046,P12956,P62993,Q92547,Q70UQ0,Q16539,Q96RU2
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
344,566,413,691,102,7,124,301,107,17,587,652,349,575,92
|
2999,566,931,814,2943,2976,691,17,2245,1912,7,2835,1027,936,344,2540,1558,587,825,1928,1184,1353,2149,413,107,575,2732,1620,1193,2039,1889,349,652,92,3173,102,124,301,879,740
|
-0.8508280371004248,0.6516615278677587,0.32347952895027443,0.39961706105910194,-0.7972362829735179,-0.8240144161249287,0.5007536343265028,4.441103682259946,-0.3734383603785469,-0.2166706010189041,5.4400213336505425,-0.7171125997850363,0.2470934090651916,0.32347952895027443,1.0249143581417541,-0.5313590718804885,-0.035180219401076525,0.6265756372169713,0.39961706105910194,-0.2166706010189041,0.14485178548258162,0.06787023399176167,-0.3210563089295906,0.9011180973452062,2.089793763639897,0.6516615278677587,-0.6373004507569276,-0.0610168199068948,0.14485178548258162,-0.26880087001046804,-0.1906519624283154,1.0249143581417541,0.551161465774754,2.2318502116319068,-1.012467779172713,2.1372248000072944,1.994691867614015,1.1235171691084074,0.37426526772845303,0.4755098070522078
| 3,425
|
Beta catenin independent wnt signaling
| 10
| 56
| 2.248966
| 0.024515
|
P28070,P28072,Q06323,Q99436,Q9UL46,P49721,P28074,P20618,O00231,P25787
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
289,194,291,232,294,103,139,270,88,57
|
88,2670,304,2234,1543,1643,1491,2488,2580,815,1595,988,1176,270,2759,57,1710,2722,1816,289,194,139,2795,1917,2346,1922,1605,1876,103,1824,625,2025,699,1104,506,1722,1503,2876,1973,1927,1832,1880,291,1929,2808,1884,414,1454,733,2775,232,1415,1316,1371,294,1692
|
2.2318502116319068,-0.6107646440167533,1.098902204500058,-0.3734383603785469,-0.035180219401076525,-0.08688334071096061,-0.009373375282462895,-0.5049571593465545,-0.5577941570157251,0.39961706105910194,-0.0610168199068948,0.2725833089167855,0.14485178548258162,1.1972206297942891,-0.6638702399151422,2.8163886227017083,-0.11277994734734909,-0.6373004507569276,-0.16466408850858408,1.1481084899134386,1.5142122212082996,1.827480517995054,-0.6904742194938005,-0.2166706010189041,-0.42594849699032294,-0.2166706010189041,-0.0610168199068948,-0.1906519624283154,2.113519207995092,-0.16466408850858408,0.576325735394843,-0.26880087001046804,0.5007536343265028,0.1960292991597587,0.7517476513909233,-0.11277994734734909,-0.009373375282462895,-0.7437855934072211,-0.24272017828745532,-0.2166706010189041,-0.16466408850858408,-0.1906519624283154,1.1481084899134386,-0.2166706010189041,-0.6904742194938005,-0.1906519624283154,0.9011180973452062,0.01640387475979311,0.4755098070522078,-0.6638702399151422,1.3683838826407642,0.0421516914587663,0.0935596600019327,0.06787023399176167,1.1481084899134386,-0.08688334071096061
| 3,425
|
T cell receptor signaling pathway
| 7
| 19
| 2.239139
| 0.025147
|
P31749,P62993,O15111,P27361,Q16539,O96013,P31751
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
69,587,464,396,575,501,95
|
2007,464,501,888,1096,396,1023,69,95,1285,1394,587,1397,1929,1449,2362,575,1860,719
|
-0.26880087001046804,0.8016379926908211,0.7517476513909233,0.3488861372872074,0.1960292991597587,0.9259261957288346,0.2470934090651916,2.4904786675716095,2.1845767415122475,0.0935596600019327,0.0421516914587663,0.6265756372169713,0.0421516914587663,-0.2166706010189041,0.01640387475979311,-0.42594849699032294,0.6516615278677587,-0.16466408850858408,0.5007536343265028
| 3,425
|
Response to light stimulus
| 14
| 63
| 2.238228
| 0.025206
|
P22830,Q15555,P50570,P46934,P31749,P05067,Q8N163,Q96K76,Q06787,Q14011,Q9BRK5,Q96RU2,P27544,P31751
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
1,415,344,261,69,266,18,55,370,53,283,92,279,95
|
2999,428,931,2976,266,857,2386,3180,691,1230,2071,1596,818,536,1,279,933,2677,1097,69,95,3380,2495,1027,936,261,344,2084,1345,1556,1558,2841,3185,1725,1398,370,1563,1353,2149,1665,53,611,728,415,2553,2732,1359,2928,18,2459,3414,55,1305,2705,92,283,1311,1313,2620,1586,1905,2751,1957
|
-0.8508280371004248,0.876285345323554,0.32347952895027443,-0.8240144161249287,1.2217416615359413,0.37426526772845303,-0.4522520658646618,-1.0395362564915789,0.5007536343265028,0.11922012561949845,-0.2949128537598711,-0.0610168199068948,0.39961706105910194,0.7017558262776622,6.931947993482619,1.1726762745538093,0.32347952895027443,-0.6107646440167533,0.1960292991597587,2.4904786675716095,2.1845767415122475,-1.8135990510739965,-0.5049571593465545,0.2470934090651916,0.32347952895027443,1.246239474826163,1.0249143581417541,-0.2949128537598711,0.06787023399176167,-0.035180219401076525,-0.035180219401076525,-0.7171125997850363,-1.0395362564915789,-0.11277994734734909,0.0421516914587663,0.9754688945658373,-0.035180219401076525,0.06787023399176167,-0.3210563089295906,-0.08688334071096061,2.8857686722684996,0.6014637492767998,0.4755098070522078,0.9011180973452062,-0.5313590718804885,-0.6373004507569276,0.06787023399176167,-0.7704934153422345,4.441103682259946,-0.4785882223380154,-2.9840385677076027,2.8857686722684996,0.0935596600019327,-0.6107646440167533,2.2318502116319068,1.1726762745538093,0.0935596600019327,0.0935596600019327,-0.5577941570157251,-0.035180219401076525,-0.1906519624283154,-0.6373004507569276,-0.2166706010189041
| 3,425
|
Muscle contraction
| 8
| 29
| 2.235944
| 0.025355
|
P67936,P05023,P09493,P08670,Q13555,P28289,Q9HD47,O43865
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
220,41,106,109,113,172,277,181
|
181,814,41,1434,569,2490,3235,109,106,2442,988,2793,1600,1233,172,934,2398,2728,220,1108,2917,1449,113,3118,2362,2854,277,285,1810
|
1.5626444707730802,0.39961706105910194,3.1617288490354225,0.01640387475979311,0.6516615278677587,-0.5049571593465545,-1.1209668411577562,2.066048387611596,2.089793763639897,-0.4785882223380154,0.2725833089167855,-0.6904742194938005,-0.0610168199068948,0.11922012561949845,1.5868278002986016,0.32347952895027443,-0.4522520658646618,-0.6373004507569276,1.3927445446390339,0.1960292991597587,-0.7704934153422345,0.01640387475979311,2.0422830000109147,-0.9584419344202308,-0.42594849699032294,-0.7171125997850363,1.1972206297942891,1.1726762745538093,-0.1387068069964346
| 3,425
|
Mitochondrial transport
| 16
| 94
| 2.235086
| 0.025412
|
P49257,O95831,Q9Y5J7,O60830,P00846,O95429,Q99595,Q9NS69,O43772,O43615,P10809,P55786,P23786,Q9Y5J9,Q9Y584,O14737
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
252,3,233,5,38,101,8,72,10,73,15,19,149,218,60,157
|
582,961,157,1486,853,73,10,5,1642,2904,2753,1707,607,2067,1492,3112,101,3087,3,2240,38,2976,2944,568,2242,2243,15,1814,1769,149,3267,782,3315,1097,3387,2586,2761,1715,522,3134,252,1822,1285,1823,2591,2641,19,1182,1072,1778,346,1353,1835,443,1837,2732,1037,453,509,2363,1250,2558,3120,1675,2458,292,2511,1470,2108,470,838,2969,8,877,2778,2564,2115,2221,72,2826,1903,2001,1324,547,1271,2858,2431,922,1378,60,2861,233,218,1379
|
0.6265756372169713,0.29804530062961365,1.683344653281223,-0.009373375282462895,0.37426526772845303,2.373205898373848,5.009094029804443,5.738741189752724,-0.08688334071096061,-0.7704934153422345,-0.6638702399151422,-0.11277994734734909,0.6014637492767998,-0.2949128537598711,-0.009373375282462895,-0.9584419344202308,2.1372248000072944,-0.9314840880697907,6.014053113653133,-0.3734383603785469,3.298795814228332,-0.8240144161249287,-0.7972362829735179,0.6516615278677587,-0.3734383603785469,-0.3734383603785469,4.726233902247758,-0.16466408850858408,-0.1387068069964346,1.7555075594715182,-1.2027404258895786,0.42494165677844037,-1.3398110388904214,0.1960292991597587,-1.9269323014404063,-0.5577941570157251,-0.6638702399151422,-0.11277994734734909,0.72676448575094,-0.9854364187655524,1.2707141738685634,-0.16466408850858408,0.0935596600019327,-0.16466408850858408,-0.5577941570157251,-0.5842626139461844,4.419074039669878,0.14485178548258162,0.2215754549719998,-0.1387068069964346,1.0249143581417541,0.06787023399176167,-0.16466408850858408,0.8514278226896782,-0.16466408850858408,-0.6373004507569276,0.2470934090651916,0.8265454114723118,0.7517476513909233,-0.42594849699032294,0.11922012561949845,-0.5313590718804885,-0.9584419344202308,-0.08688334071096061,-0.4785882223380154,1.1481084899134386,-0.5049571593465545,0.01640387475979311,-0.2949128537598711,0.8016379926908211,0.39961706105910194,-0.7972362829735179,5.160492534890691,0.37426526772845303,-0.6638702399151422,-0.5313590718804885,-0.2949128537598711,-0.3472314167626071,2.396698193300339,-0.6904742194938005,-0.1906519624283154,-0.24272017828745532,0.0935596600019327,0.7017558262776622,0.11922012561949845,-0.7171125997850363,-0.4522520658646618,0.3488861372872074,0.06787023399176167,2.7932266034927613,-0.7171125997850363,1.3683838826407642,1.417082700426686,0.06787023399176167
| 3,425
|
Response to oxygen levels
| 7
| 64
| 2.235047
| 0.025414
|
P30519,O95831,P00846,P31749,P00813,P55786,P00558
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
33,3,38,69,14,19,116
|
1170,2974,1172,666,1962,1761,3,116,14,38,1339,1494,690,2943,2976,1434,3247,2282,1141,932,2529,2246,1548,536,1603,33,1773,69,1920,2534,819,1027,1715,1717,2084,2641,19,1105,1928,1833,1353,729,199,730,3044,1462,1196,324,1413,910,3190,2701,615,2303,3347,656,683,879,800,3053,2228,497,3131,3086
|
0.14485178548258162,-0.8240144161249287,0.14485178548258162,0.5259708094615214,-0.24272017828745532,-0.1387068069964346,6.014053113653133,2.0184975203635163,4.748071870065068,3.298795814228332,0.06787023399176167,-0.009373375282462895,0.5007536343265028,-0.7972362829735179,-0.8240144161249287,0.01640387475979311,-1.1481862519519852,-0.3996773248018237,0.170454792757679,0.32347952895027443,-0.5313590718804885,-0.3734383603785469,-0.035180219401076525,0.7017558262776622,-0.0610168199068948,3.4352707473423414,-0.1387068069964346,2.4904786675716095,-0.2166706010189041,-0.5313590718804885,0.39961706105910194,0.2470934090651916,-0.11277994734734909,-0.11277994734734909,-0.2949128537598711,-0.5842626139461844,4.419074039669878,0.1960292991597587,-0.2166706010189041,-0.16466408850858408,0.06787023399176167,0.4755098070522078,1.4899631123019665,0.4755098070522078,-0.8776773707245988,0.01640387475979311,0.14485178548258162,1.0742634875654984,0.0421516914587663,0.3488861372872074,-1.0395362564915789,-0.6107646440167533,0.6014637492767998,-0.3996773248018237,-1.4501903172702728,0.551161465774754,0.5259708094615214,0.37426526772845303,0.42494165677844037,-0.8776773707245988,-0.3472314167626071,0.776705446342711,-0.9584419344202308,-0.9045626443840719
| 3,425
|
Bulbar signs
| 8
| 15
| 2.233837
| 0.025494
|
P07602,P35637,P00846,Q92734,Q15043,Q99720,O43681,P03886
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
251,131,38,486,430,20,427,27
|
427,38,27,690,2489,569,251,3356,131,1655,430,486,20,2426,1536
|
0.876285345323554,3.298795814228332,3.8860619373950085,0.5007536343265028,-0.5049571593465545,0.6516615278677587,1.2707141738685634,-1.505627144578314,1.899265883808607,-0.08688334071096061,0.876285345323554,0.776705446342711,4.374972711166257,-0.4522520658646618,-0.009373375282462895
| 3,425
|
Adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
| 8
| 37
| 2.22781
| 0.025893
|
P30511,Q9NUQ9,Q5RKV6,P00813,P10809,P60033,Q07021,Q9UQ84
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
34,327,200,14,15,272,399,156
|
2126,1961,2281,1910,14,2830,1494,814,1227,1646,15,34,2678,586,671,819,936,1345,861,272,1398,399,1184,3322,2362,200,3045,1889,904,1943,2266,487,1367,1053,1584,327,156
|
-0.3210563089295906,-0.24272017828745532,-0.3996773248018237,-0.2166706010189041,4.748071870065068,-0.7171125997850363,-0.009373375282462895,0.39961706105910194,0.11922012561949845,-0.08688334071096061,4.726233902247758,3.412565525129457,-0.6107646440167533,0.6265756372169713,0.5259708094615214,0.39961706105910194,0.32347952895027443,0.06787023399176167,0.37426526772845303,1.1972206297942891,0.0421516914587663,0.9259261957288346,0.14485178548258162,-1.367344786047239,-0.42594849699032294,1.4899631123019665,-0.8776773707245988,-0.1906519624283154,0.3488861372872074,-0.2166706010189041,-0.3734383603785469,0.776705446342711,0.06787023399176167,0.2470934090651916,-0.035180219401076525,1.0742634875654984,1.7074202081888503
| 3,425
|
Tachycardia
| 7
| 26
| 2.223362
| 0.026191
|
O43772,P09493,P23786,Q9HD47,P50336,Q01130,P42892
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
10,106,149,277,309,211,25
|
10,2280,1339,2389,106,2392,1390,2531,1971,149,2081,2980,1714,25,320,452,309,211,1562,2690,833,3261,2854,3051,277,2895
|
5.009094029804443,-0.3996773248018237,0.06787023399176167,-0.4522520658646618,2.089793763639897,-0.4522520658646618,0.0421516914587663,-0.5313590718804885,-0.24272017828745532,1.7555075594715182,-0.2949128537598711,-0.8240144161249287,-0.11277994734734909,3.9531504082961226,1.0742634875654984,0.8265454114723118,1.098902204500058,1.4413984485653908,-0.035180219401076525,-0.6107646440167533,0.39961706105910194,-1.175444027337681,-0.7171125997850363,-0.8776773707245988,1.1972206297942891,-0.7437855934072211
| 3,425
|
Sodium ion transport
| 8
| 26
| 2.221064
| 0.026347
|
P50570,P46934,P31749,P05023,Q9HD47,O43865,Q9Y6M7,Q96PU5
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
344,261,69,41,277,181,331,159
|
1333,1172,181,2334,41,1434,2387,3268,69,261,891,344,2398,2197,1031,1294,3210,444,2037,159,2304,1522,277,1860,2429,331
|
0.06787023399176167,0.14485178548258162,1.5626444707730802,-0.42594849699032294,3.1617288490354225,0.01640387475979311,-0.4522520658646618,-1.2027404258895786,2.4904786675716095,1.246239474826163,0.3488861372872074,1.0249143581417541,-0.4522520658646618,-0.3472314167626071,0.2470934090651916,0.0935596600019327,-1.0666420944020525,0.8514278226896782,-0.26880087001046804,1.683344653281223,-0.3996773248018237,-0.009373375282462895,1.1972206297942891,-0.16466408850858408,-0.4522520658646618,1.0742634875654984
| 3,425
|
Response to uv
| 9
| 43
| 2.190885
| 0.02846
|
P46934,P31749,Q8N163,Q96K76,Q06787,Q14011,Q9BRK5,Q96RU2,P27544
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
261,69,18,55,370,53,283,92,279
|
2999,428,2976,857,3180,691,1230,2071,1596,818,536,279,933,69,2495,1027,936,261,1345,1556,1558,1398,370,1563,1353,1665,53,611,728,2553,2732,1359,2928,18,55,1305,2705,92,283,1313,2620,1905,2751
|
-0.8508280371004248,0.876285345323554,-0.8240144161249287,0.37426526772845303,-1.0395362564915789,0.5007536343265028,0.11922012561949845,-0.2949128537598711,-0.0610168199068948,0.39961706105910194,0.7017558262776622,1.1726762745538093,0.32347952895027443,2.4904786675716095,-0.5049571593465545,0.2470934090651916,0.32347952895027443,1.246239474826163,0.06787023399176167,-0.035180219401076525,-0.035180219401076525,0.0421516914587663,0.9754688945658373,-0.035180219401076525,0.06787023399176167,-0.08688334071096061,2.8857686722684996,0.6014637492767998,0.4755098070522078,-0.5313590718804885,-0.6373004507569276,0.06787023399176167,-0.7704934153422345,4.441103682259946,2.8857686722684996,0.0935596600019327,-0.6107646440167533,2.2318502116319068,1.1726762745538093,0.0935596600019327,-0.5577941570157251,-0.1906519624283154,-0.6373004507569276
| 3,425
|
Cilium
| 28
| 97
| 2.189776
| 0.02854
|
Q8NCM8,Q96J42,P05067,P10809,O75665,Q9Y5Y2,P41208,Q16181,P28070,Q15555,P04350,Q5SW79,P05023,Q2M1P5,Q9Y5K8,Q9Y366,Q15388,O43805,Q9NUQ9,P31749,O43924,Q10713,Q8IUD2,O95721,P09622,Q15154,P35613,A6NIH7
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
133,140,266,15,150,286,158,416,289,415,408,170,41,299,438,52,443,62,327,69,82,346,212,340,99,358,227,122
|
476,122,2233,1333,662,1279,62,82,2865,150,3111,340,1709,814,408,41,1434,266,2016,2388,1595,99,1968,15,1597,2633,1389,988,2793,753,2675,2908,289,2677,69,649,227,783,2250,158,2682,1284,1874,1607,1656,2396,2398,2687,2914,1610,1878,2289,3271,3388,896,346,1931,1513,790,1355,358,443,415,676,416,299,170,2734,1466,212,133,1301,2849,2700,458,2741,1895,140,1004,2048,840,1209,2371,1266,1630,327,2617,2856,2475,3333,2003,1215,52,1539,438,286,2378
|
0.776705446342711,1.994691867614015,-0.3734383603785469,0.06787023399176167,0.5259708094615214,0.0935596600019327,2.7236336326597668,2.255457712363717,-0.7437855934072211,1.7314744805213913,-0.9584419344202308,1.0249143581417541,-0.11277994734734909,0.39961706105910194,0.9011180973452062,3.1617288490354225,0.01640387475979311,1.2217416615359413,-0.26880087001046804,-0.4522520658646618,-0.0610168199068948,2.160910618443281,-0.24272017828745532,4.726233902247758,-0.0610168199068948,-0.5842626139461844,0.0421516914587663,0.2725833089167855,-0.6904742194938005,0.45023919311681804,-0.6107646440167533,-0.7704934153422345,1.1481084899134386,-0.6107646440167533,2.4904786675716095,0.551161465774754,1.3683838826407642,0.42494165677844037,-0.3734383603785469,1.683344653281223,-0.6107646440167533,0.0935596600019327,-0.1906519624283154,-0.0610168199068948,-0.08688334071096061,-0.4522520658646618,-0.4522520658646618,-0.6107646440167533,-0.7704934153422345,-0.0610168199068948,-0.1906519624283154,-0.3996773248018237,-1.2027404258895786,-1.9269323014404063,0.3488861372872074,1.0249143581417541,-0.2166706010189041,-0.009373375282462895,0.42494165677844037,0.06787023399176167,1.0002037240901964,0.8514278226896782,0.9011180973452062,0.5259708094615214,0.9011180973452062,1.1235171691084074,1.6109893910257655,-0.6373004507569276,0.01640387475979311,1.4413984485653908,1.875358128951854,0.0935596600019327,-0.7171125997850363,-0.6107646440167533,0.8265454114723118,-0.6373004507569276,-0.1906519624283154,1.827480517995054,0.2725833089167855,-0.26880087001046804,0.39961706105910194,0.14485178548258162,-0.42594849699032294,0.11922012561949845,-0.0610168199068948,1.0742634875654984,-0.5577941570157251,-0.7171125997850363,-0.4785882223380154,-1.3949190573747474,-0.24272017828745532,0.14485178548258162,2.931934335739412,-0.009373375282462895,0.876285345323554,1.1726762745538093,-0.42594849699032294
| 3,425
|
Sodium ion transmembrane transport
| 6
| 21
| 2.188138
| 0.02866
|
P50570,P46934,P05023,Q9HD47,Q9Y6M7,Q96PU5
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
344,261,41,277,331,159
|
1333,1172,2334,41,1434,2387,3268,261,891,344,2398,2197,1031,1294,444,2037,159,1522,277,1860,331
|
0.06787023399176167,0.14485178548258162,-0.42594849699032294,3.1617288490354225,0.01640387475979311,-0.4522520658646618,-1.2027404258895786,1.246239474826163,0.3488861372872074,1.0249143581417541,-0.4522520658646618,-0.3472314167626071,0.2470934090651916,0.0935596600019327,0.8514278226896782,-0.26880087001046804,1.683344653281223,-0.009373375282462895,1.1972206297942891,-0.16466408850858408,1.0742634875654984
| 3,425
|
Anion transmembrane transport
| 17
| 43
| 2.184993
| 0.028889
|
P33527,Q9Y619,P21796,P53985,Q14728,Q9UHG3,P08183,Q9HC21,P45880,P51790,P41440,Q9H2D1,Q4KMQ2,Q9UJS0,P30825,Q9BQT8,Q9Y6M7
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
219,234,132,411,230,9,138,268,522,238,573,472,444,547,209,94,331
|
884,3265,583,1706,2788,2944,2386,138,2387,1814,2492,132,209,219,573,522,238,2840,411,2197,2916,2353,230,1569,1457,444,3021,1045,1992,94,2112,472,3262,3105,268,2116,2001,9,547,3176,1216,234,331
|
0.3488861372872074,-1.2027404258895786,0.6265756372169713,-0.11277994734734909,-0.6904742194938005,-0.7972362829735179,-0.4522520658646618,1.827480517995054,-0.4522520658646618,-0.16466408850858408,-0.5049571593465545,1.875358128951854,1.4413984485653908,1.3927445446390339,0.6516615278677587,0.72676448575094,1.3440006150915877,-0.7171125997850363,0.9011180973452062,-0.3472314167626071,-0.7704934153422345,-0.42594849699032294,1.3683838826407642,-0.035180219401076525,0.01640387475979311,0.8514278226896782,-0.8508280371004248,0.2470934090651916,-0.24272017828745532,2.2082232468714693,-0.2949128537598711,0.8016379926908211,-1.175444027337681,-0.9314840880697907,1.2217416615359413,-0.2949128537598711,-0.24272017828745532,5.05241487928429,0.7017558262776622,-1.012467779172713,0.14485178548258162,1.3683838826407642,1.0742634875654984
| 3,425
|
Ciliopathies
| 6
| 20
| 2.181241
| 0.029166
|
Q8NCM8,Q2M1P5,O43924,Q10713,Q9Y366,O75665
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
133,299,82,346,52,150
|
82,150,3111,2250,1656,346,415,299,1466,133,2849,1364,2741,2048,840,1951,842,581,2003,52
|
2.255457712363717,1.7314744805213913,-0.9584419344202308,-0.3734383603785469,-0.08688334071096061,1.0249143581417541,0.9011180973452062,1.1235171691084074,0.01640387475979311,1.875358128951854,-0.7171125997850363,0.06787023399176167,-0.6373004507569276,-0.26880087001046804,0.39961706105910194,-0.2166706010189041,0.39961706105910194,0.6516615278677587,-0.24272017828745532,2.931934335739412
| 3,425
|
Protein localization
| 29
| 83
| 2.176165
| 0.029543
|
P49069,P21796,O60830,Q99595,P05067,P10809,Q2T9J0,Q9NR77,Q9UJS0,P46379,Q9NRP2,O43681,Q9Y584,Q15388,O14975,P08574,Q7L5D6,Q9NS69,O43615,Q10713,Q13011,Q13505,Q9Y5J9,Q9NX63,Q9Y5J7,Q5JRX3,O15254,O75874,P40855
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
504,132,5,8,266,15,274,544,547,47,314,427,60,443,563,570,195,72,73,346,83,84,218,492,233,509,108,355,368
|
1541,806,1486,563,773,108,73,427,1700,3265,5,1226,3351,2904,2753,3245,1706,355,2067,3289,2240,2975,266,568,570,3352,1141,15,1814,2492,1388,132,2285,782,1915,3395,1652,3290,368,47,504,860,2592,2912,698,3037,346,83,2093,84,791,443,274,1037,509,1249,195,1675,2458,2660,2511,1364,2108,8,3124,2745,2115,544,314,72,492,3215,2276,547,2858,2430,922,1378,60,2861,233,218,1379
|
-0.035180219401076525,0.39961706105910194,-0.009373375282462895,0.6516615278677587,0.42494165677844037,2.066048387611596,2.373205898373848,0.876285345323554,-0.11277994734734909,-1.2027404258895786,5.738741189752724,0.11922012561949845,-1.4778878873050318,-0.7704934153422345,-0.6638702399151422,-1.1481862519519852,-0.11277994734734909,1.0002037240901964,-0.2949128537598711,-1.2574501425253701,-0.3734383603785469,-0.8240144161249287,1.2217416615359413,0.6516615278677587,0.6516615278677587,-1.4778878873050318,0.170454792757679,4.726233902247758,-0.16466408850858408,-0.5049571593465545,0.0421516914587663,1.875358128951854,-0.3996773248018237,0.42494165677844037,-0.2166706010189041,-2.0696593498646267,-0.08688334071096061,-1.2574501425253701,0.9754688945658373,3.0240574327600016,0.7517476513909233,0.37426526772845303,-0.5577941570157251,-0.7704934153422345,0.5007536343265028,-0.8776773707245988,1.0249143581417541,2.255457712363717,-0.2949128537598711,2.255457712363717,0.42494165677844037,0.8514278226896782,1.1972206297942891,0.2470934090651916,0.7517476513909233,0.11922012561949845,1.5142122212082996,-0.08688334071096061,-0.4785882223380154,-0.5842626139461844,-0.5049571593465545,0.06787023399176167,-0.2949128537598711,5.160492534890691,-0.9584419344202308,-0.6373004507569276,-0.2949128537598711,0.7017558262776622,1.098902204500058,2.396698193300339,0.776705446342711,-1.0666420944020525,-0.3734383603785469,0.7017558262776622,-0.7171125997850363,-0.4522520658646618,0.3488861372872074,0.06787023399176167,2.7932266034927613,-0.7171125997850363,1.3683838826407642,1.417082700426686,0.06787023399176167
| 3,425
|
Impaired vibration sensation in the lower limbs
| 7
| 15
| 2.171325
| 0.029907
|
P00846,Q15120,P10809,Q12768,O00400,O43819,Q9NR77
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
38,199,15,174,235,516,544
|
235,746,516,777,2332,38,15,2500,2256,174,199,1733,2774,543,544
|
1.3440006150915877,0.45023919311681804,0.72676448575094,0.42494165677844037,-0.42594849699032294,3.298795814228332,4.726233902247758,-0.5049571593465545,-0.3734383603785469,1.5868278002986016,1.4899631123019665,-0.11277994734734909,-0.6638702399151422,0.7017558262776622,0.7017558262776622
| 3,425
|
Urinary incontinence
| 11
| 49
| 2.167853
| 0.03017
|
P07602,P50570,P35637,P31749,Q9NP73,P10809,Q12768,Q99720,Q06787,P07196,Q9NQ11
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
251,344,131,69,269,15,174,20,370,188,31
|
427,2127,777,2975,188,2526,251,3384,2389,15,932,3356,2020,1500,1916,69,131,344,2084,3158,1658,2195,2500,2256,2449,370,1242,174,3159,1037,2460,908,2774,1364,1081,2969,20,953,2166,2271,711,269,31,2426,581,2003,2228,1168,2623
|
0.876285345323554,-0.3210563089295906,0.42494165677844037,-0.8240144161249287,1.5384393090995059,-0.5313590718804885,1.2707141738685634,-1.8985293990653853,-0.4522520658646618,4.726233902247758,0.32347952895027443,-1.505627144578314,-0.26880087001046804,-0.009373375282462895,-0.2166706010189041,2.4904786675716095,1.899265883808607,1.0249143581417541,-0.2949128537598711,-1.012467779172713,-0.08688334071096061,-0.3472314167626071,-0.5049571593465545,-0.3734383603785469,-0.4785882223380154,0.9754688945658373,0.11922012561949845,1.5868278002986016,-1.012467779172713,0.2470934090651916,-0.4785882223380154,0.3488861372872074,-0.6638702399151422,0.06787023399176167,0.2215754549719998,-0.7972362829735179,4.374972711166257,0.32347952895027443,-0.3210563089295906,-0.3734383603785469,0.5007536343265028,1.2217416615359413,3.5485562599914546,-0.4522520658646618,0.6516615278677587,-0.24272017828745532,-0.3472314167626071,0.170454792757679,-0.5577941570157251
| 3,425
|
Neuron apoptotic process
| 7
| 50
| 2.167167
| 0.030222
|
O95831,Q01105,P50897,Q99720,P07196,Q9NR28,P31751
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
3,104,203,20,188,224,95
|
1382,665,987,1909,3,2489,2943,3152,2976,266,2016,188,2018,1141,691,1870,95,2795,1917,1027,936,858,503,1717,1718,203,2084,696,1556,1394,1347,524,1725,104,2449,1978,788,995,1112,1893,2853,615,418,3213,2990,20,2271,224,1132,3131
|
0.0421516914587663,0.5259708094615214,0.2725833089167855,-0.2166706010189041,6.014053113653133,-0.5049571593465545,-0.7972362829735179,-1.012467779172713,-0.8240144161249287,1.2217416615359413,-0.26880087001046804,1.5384393090995059,-0.26880087001046804,0.170454792757679,0.5007536343265028,-0.1906519624283154,2.1845767415122475,-0.6904742194938005,-0.2166706010189041,0.2470934090651916,0.32347952895027443,0.37426526772845303,0.7517476513909233,-0.11277994734734909,-0.11277994734734909,1.4656918868469564,-0.2949128537598711,0.5007536343265028,-0.035180219401076525,0.0421516914587663,0.06787023399176167,0.72676448575094,-0.11277994734734909,2.113519207995092,-0.4785882223380154,-0.24272017828745532,0.42494165677844037,0.2725833089167855,0.1960292991597587,-0.1906519624283154,-0.7171125997850363,0.6014637492767998,0.9011180973452062,-1.0666420944020525,-0.8240144161249287,4.374972711166257,-0.3734383603785469,1.3927445446390339,0.1960292991597587,-0.9584419344202308
| 3,425
|
Lipid localization
| 15
| 80
| 2.166393
| 0.030281
|
Q8WTV0,P33527,Q9BZF3,P31749,Q9H6V9,P14174,O15260,O43772,P08183,Q96AA3,Q99720,P23786,Q9H4L5,Q9BQE5,P31751
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
130,219,4,69,39,71,198,10,138,214,20,149,185,30,95
|
1425,2625,3410,563,380,198,884,10,3265,1138,1140,2333,2069,931,3300,2489,814,534,2490,251,3384,2241,138,932,71,2634,2532,2285,149,1915,2636,3387,69,95,2187,219,890,1919,937,1823,3066,1975,1398,3208,826,1353,1296,726,444,2844,2411,1119,1301,130,214,2162,636,20,30,1264,2111,1799,2051,4,2167,185,1630,39,2995,1858,2426,3215,379,660,687,1271,2121,922,1061,718
|
0.01640387475979311,-0.5842626139461844,-2.712917271715438,0.6516615278677587,0.950709756463659,1.4899631123019665,0.3488861372872074,5.009094029804443,-1.2027404258895786,0.170454792757679,0.170454792757679,-0.42594849699032294,-0.2949128537598711,0.32347952895027443,-1.2848639936597672,-0.5049571593465545,0.39961706105910194,0.7017558262776622,-0.5049571593465545,1.2707141738685634,-1.8985293990653853,-0.3734383603785469,1.827480517995054,0.32347952895027443,2.467061710936354,-0.5842626139461844,-0.5313590718804885,-0.3996773248018237,1.7555075594715182,-0.2166706010189041,-0.5842626139461844,-1.9269323014404063,2.4904786675716095,2.1845767415122475,-0.3472314167626071,1.3927445446390339,0.3488861372872074,-0.2166706010189041,0.32347952895027443,-0.16466408850858408,-0.9045626443840719,-0.24272017828745532,0.0421516914587663,-1.0666420944020525,0.39961706105910194,0.06787023399176167,0.0935596600019327,0.4755098070522078,0.8514278226896782,-0.7171125997850363,-0.4522520658646618,0.1960292991597587,0.0935596600019327,1.9231530513553758,1.4413984485653908,-0.3210563089295906,0.576325735394843,4.374972711166257,3.6163370124132777,0.11922012561949845,-0.2949128537598711,-0.1387068069964346,-0.26880087001046804,5.950692891080032,-0.3210563089295906,1.5626444707730802,-0.0610168199068948,3.2759927630672006,-0.8240144161249287,-0.16466408850858408,-0.4522520658646618,-1.0666420944020525,0.9754688945658373,0.551161465774754,0.5259708094615214,0.11922012561949845,-0.2949128537598711,0.3488861372872074,0.2470934090651916,0.5007536343265028
| 3,425
|
Uch proteinases
| 10
| 47
| 2.16006
| 0.030768
|
P28070,P28072,Q06323,Q99436,Q9UL46,P49721,P28074,P20618,O00231,P25787
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
289,194,291,232,294,103,139,270,88,57
|
88,2670,304,2234,2008,1543,1643,2719,1176,270,2759,57,1710,2722,1816,289,194,139,2346,1922,1605,1876,103,3158,1824,2025,1104,506,1722,1503,2876,1241,291,2808,414,1454,2809,2211,733,232,1415,2969,294,1692,3083,1134,2321
|
2.2318502116319068,-0.6107646440167533,1.098902204500058,-0.3734383603785469,-0.26880087001046804,-0.035180219401076525,-0.08688334071096061,-0.6373004507569276,0.14485178548258162,1.1972206297942891,-0.6638702399151422,2.8163886227017083,-0.11277994734734909,-0.6373004507569276,-0.16466408850858408,1.1481084899134386,1.5142122212082996,1.827480517995054,-0.42594849699032294,-0.2166706010189041,-0.0610168199068948,-0.1906519624283154,2.113519207995092,-1.012467779172713,-0.16466408850858408,-0.26880087001046804,0.1960292991597587,0.7517476513909233,-0.11277994734734909,-0.009373375282462895,-0.7437855934072211,0.11922012561949845,1.1481084899134386,-0.6904742194938005,0.9011180973452062,0.01640387475979311,-0.6904742194938005,-0.3472314167626071,0.4755098070522078,1.3683838826407642,0.0421516914587663,-0.7972362829735179,1.1481084899134386,-0.08688334071096061,-0.9045626443840719,0.1960292991597587,-0.3996773248018237
| 3,425
|
Cytoprotection by hmox1
| 13
| 68
| 2.157844
| 0.03094
|
P30519,P28070,Q06323,Q8N8Q8,P28072,Q9UL46,P33527,Q99436,P49721,P28074,P20618,O00231,P25787
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
33,289,291,292,194,294,219,232,103,139,270,88,57
|
88,2670,2716,304,2124,2234,1543,516,963,1643,1021,1386,1141,2335,2136,1232,2072,1176,1769,270,721,2759,57,1710,2722,1816,289,194,139,1234,33,219,2346,671,2251,1922,1605,1876,103,1824,2726,2025,1104,506,1722,1503,2876,1107,1560,1398,291,2808,2203,1188,1931,414,1454,828,679,292,3371,733,737,2306,232,1415,294,1692
|
2.2318502116319068,-0.6107646440167533,-0.6373004507569276,1.098902204500058,-0.3210563089295906,-0.3734383603785469,-0.035180219401076525,0.72676448575094,0.29804530062961365,-0.08688334071096061,0.2470934090651916,0.0421516914587663,0.170454792757679,-0.42594849699032294,-0.3210563089295906,0.11922012561949845,-0.2949128537598711,0.14485178548258162,-0.1387068069964346,1.1972206297942891,0.4755098070522078,-0.6638702399151422,2.8163886227017083,-0.11277994734734909,-0.6373004507569276,-0.16466408850858408,1.1481084899134386,1.5142122212082996,1.827480517995054,0.11922012561949845,3.4352707473423414,1.3927445446390339,-0.42594849699032294,0.5259708094615214,-0.3734383603785469,-0.2166706010189041,-0.0610168199068948,-0.1906519624283154,2.113519207995092,-0.16466408850858408,-0.6373004507569276,-0.26880087001046804,0.1960292991597587,0.7517476513909233,-0.11277994734734909,-0.009373375282462895,-0.7437855934072211,0.1960292991597587,-0.035180219401076525,0.0421516914587663,1.1481084899134386,-0.6904742194938005,-0.3472314167626071,0.14485178548258162,-0.2166706010189041,0.9011180973452062,0.01640387475979311,0.39961706105910194,0.5259708094615214,1.1481084899134386,-1.5890980607614524,0.4755098070522078,0.4755098070522078,-0.3996773248018237,1.3683838826407642,0.0421516914587663,1.1481084899134386,-0.08688334071096061
| 3,425
|
Vascular process in circulatory system
| 17
| 34
| 2.15747
| 0.030969
|
P33527,O75116,P53985,Q07954,P48507,P08183,Q9HB40,Q99808,Q9UDY2,P52306,Q13464,O15439,P41440,P30825,P42892,Q93063,Q16625
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
219,666,411,826,858,138,405,656,406,478,788,884,573,209,25,734,612
|
1697,1333,884,2752,666,1490,1494,2943,1812,138,932,1233,209,219,573,25,858,478,411,2197,2548,1447,826,788,1402,1457,612,2411,734,1796,2304,656,405,406
|
-0.11277994734734909,0.06787023399176167,0.3488861372872074,-0.6638702399151422,0.5259708094615214,-0.009373375282462895,-0.009373375282462895,-0.7972362829735179,-0.16466408850858408,1.827480517995054,0.32347952895027443,0.11922012561949845,1.4413984485653908,1.3927445446390339,0.6516615278677587,3.9531504082961226,0.37426526772845303,0.776705446342711,0.9011180973452062,-0.3472314167626071,-0.5313590718804885,0.01640387475979311,0.39961706105910194,0.42494165677844037,0.0421516914587663,0.01640387475979311,0.6014637492767998,-0.4522520658646618,0.4755098070522078,-0.1387068069964346,-0.3996773248018237,0.551161465774754,0.9259261957288346,0.9259261957288346
| 3,425
|
Dna replication pre initiation
| 14
| 64
| 2.156818
| 0.03102
|
P28070,P28072,Q06323,Q9Y619,Q99436,Q9UL46,P49721,Q9NR33,P28074,P20618,Q14566,P33991,O00231,P25787
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
289,194,291,234,232,294,103,169,139,270,310,184,88,57
|
88,2670,304,2234,1543,3060,2865,1643,1230,816,1912,1176,270,1067,520,2759,57,1710,2722,1604,1816,289,194,139,184,1651,670,2679,2346,1922,1605,1657,1554,1876,103,966,1824,2913,2025,2502,1104,506,1722,1503,2876,3377,894,291,626,2808,310,1568,414,1454,2297,733,232,1415,169,1687,3054,294,1692,234
|
2.2318502116319068,-0.6107646440167533,1.098902204500058,-0.3734383603785469,-0.035180219401076525,-0.9045626443840719,-0.7437855934072211,-0.08688334071096061,0.11922012561949845,0.39961706105910194,-0.2166706010189041,0.14485178548258162,1.1972206297942891,0.2215754549719998,0.72676448575094,-0.6638702399151422,2.8163886227017083,-0.11277994734734909,-0.6373004507569276,-0.0610168199068948,-0.16466408850858408,1.1481084899134386,1.5142122212082996,1.827480517995054,1.5626444707730802,-0.08688334071096061,0.5259708094615214,-0.6107646440167533,-0.42594849699032294,-0.2166706010189041,-0.0610168199068948,-0.08688334071096061,-0.035180219401076525,-0.1906519624283154,2.113519207995092,0.29804530062961365,-0.16466408850858408,-0.7704934153422345,-0.26880087001046804,-0.5049571593465545,0.1960292991597587,0.7517476513909233,-0.11277994734734909,-0.009373375282462895,-0.7437855934072211,-1.757207227272218,0.3488861372872074,1.1481084899134386,0.576325735394843,-0.6904742194938005,1.098902204500058,-0.035180219401076525,0.9011180973452062,0.01640387475979311,-0.3996773248018237,0.4755098070522078,1.3683838826407642,0.0421516914587663,1.6351293355923024,-0.08688334071096061,-0.8776773707245988,1.1481084899134386,-0.08688334071096061,1.3683838826407642
| 3,425
|
non-receptor serine/threonine protein kinase
| 23
| 55
| 2.150371
| 0.031526
|
Q9UHY1,Q8IV63,Q13043,P06493,Q13464,P27361,O60566,O75116,O14874,Q16539,P31749,Q15120,P78527,Q9Y5S2,P42345,O15111,P31751,Q7L7X3,Q15118,Q13555,Q86Y07,O96013,P50750
|
Functions
|
Panther Protein class
|
panther_protein_class
|
264,400,273,648,788,396,395,666,661,575,69,199,825,744,819,464,95,613,729,113,511,501,505
|
661,1279,464,395,666,501,931,648,888,988,2793,2020,1067,396,1023,69,95,2585,819,1607,1822,1285,505,2982,2085,825,3038,1725,1397,1398,273,1353,1449,3259,788,2919,113,2359,729,199,2362,1189,575,1842,613,511,400,1305,1518,1206,1949,1522,880,264,744
|
0.5259708094615214,0.0935596600019327,0.8016379926908211,0.9259261957288346,0.5259708094615214,0.7517476513909233,0.32347952895027443,0.551161465774754,0.3488861372872074,0.2725833089167855,-0.6904742194938005,-0.26880087001046804,0.2215754549719998,0.9259261957288346,0.2470934090651916,2.4904786675716095,2.1845767415122475,-0.5577941570157251,0.39961706105910194,-0.0610168199068948,-0.16466408850858408,0.0935596600019327,0.7517476513909233,-0.8240144161249287,-0.2949128537598711,0.39961706105910194,-0.8776773707245988,-0.11277994734734909,0.0421516914587663,0.0421516914587663,1.1972206297942891,0.06787023399176167,0.01640387475979311,-1.175444027337681,0.42494165677844037,-0.7704934153422345,2.0422830000109147,-0.42594849699032294,0.4755098070522078,1.4899631123019665,-0.42594849699032294,0.14485178548258162,0.6516615278677587,-0.16466408850858408,0.6014637492767998,0.7517476513909233,0.9259261957288346,0.0935596600019327,-0.009373375282462895,0.14485178548258162,-0.2166706010189041,-0.009373375282462895,0.37426526772845303,1.246239474826163,0.4755098070522078
| 3,425
|
Cellular response to ionizing radiation
| 7
| 20
| 2.143665
| 0.03206
|
P50570,O75844,Q9C0C2,P29692,Q9H1E3,P12956,Q16539
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
344,566,124,7,301,17,575
|
2999,566,931,2976,17,2245,1912,7,2835,344,2540,1558,587,1928,1184,575,1193,3173,124,301
|
-0.8508280371004248,0.6516615278677587,0.32347952895027443,-0.8240144161249287,4.441103682259946,-0.3734383603785469,-0.2166706010189041,5.4400213336505425,-0.7171125997850363,1.0249143581417541,-0.5313590718804885,-0.035180219401076525,0.6265756372169713,-0.2166706010189041,0.14485178548258162,0.6516615278677587,0.14485178548258162,-1.012467779172713,1.994691867614015,1.1235171691084074
| 3,425
|
Cholesterol biosynthesis
| 11
| 18
| 2.142026
| 0.032191
|
Q14739,Q14534,P37268,P14324,P48449,Q15125,Q15800,Q15392,O76062,Q9BWD1,Q16850
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
675,726,694,409,523,46,240,78,517,350,23
|
2065,517,409,694,523,3187,2766,2451,726,675,46,1885,78,2652,240,23,350,771
|
-0.2949128537598711,0.72676448575094,0.9011180973452062,0.5007536343265028,0.72676448575094,-1.0395362564915789,-0.6638702399151422,-0.4785882223380154,0.4755098070522078,0.5259708094615214,3.047045185687798,-0.1906519624283154,2.3026146253507402,-0.5842626139461844,1.3440006150915877,4.109169389067719,1.0249143581417541,0.45023919311681804
| 3,425
|
B cell receptor signaling pathway
| 7
| 15
| 2.135043
| 0.032757
|
P31749,P60033,P62993,P27361,Q9Y6K9,O15111,P31751
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
69,272,587,396,719,464,95
|
2007,464,396,1023,69,95,1285,272,699,587,1973,1397,1929,1860,719
|
-0.26880087001046804,0.8016379926908211,0.9259261957288346,0.2470934090651916,2.4904786675716095,2.1845767415122475,0.0935596600019327,1.1972206297942891,0.5007536343265028,0.6265756372169713,-0.24272017828745532,0.0421516914587663,-0.2166706010189041,-0.16466408850858408,0.5007536343265028
| 3,425
|
Translation factor activity rna binding
| 19
| 54
| 2.13193
| 0.033013
|
P29692,P60228,Q9ULC4,O60841,Q92905,Q7Z478,P55010,O43583,P23588,O75822,P49770,Q15056,Q9NR50,Q9Y262,P05198,O00303,Q14240,Q9UI10,O15372
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
7,893,424,775,949,832,45,552,307,333,467,868,365,495,857,115,239,644,748
|
2063,115,1865,748,552,1223,775,1383,333,857,1228,2336,1598,1497,307,1499,1602,7,2445,3205,1502,2498,467,45,2086,2350,2541,893,940,2026,1349,1395,1446,2200,1185,2204,997,1401,239,868,1464,2209,832,1939,1255,949,2465,1800,365,2376,644,424,495,1328
|
-0.2949128537598711,2.0184975203635163,-0.1906519624283154,0.45023919311681804,0.676721548752089,0.11922012561949845,0.42494165677844037,0.0421516914587663,1.0496009088870837,0.37426526772845303,0.11922012561949845,-0.42594849699032294,-0.0610168199068948,-0.009373375282462895,1.098902204500058,-0.009373375282462895,-0.0610168199068948,5.4400213336505425,-0.4785882223380154,-1.0666420944020525,-0.009373375282462895,-0.5049571593465545,0.8016379926908211,3.070015851916738,-0.2949128537598711,-0.42594849699032294,-0.5313590718804885,0.3488861372872074,0.32347952895027443,-0.26880087001046804,0.06787023399176167,0.0421516914587663,0.01640387475979311,-0.3472314167626071,0.14485178548258162,-0.3472314167626071,0.2725833089167855,0.0421516914587663,1.3440006150915877,0.37426526772845303,0.01640387475979311,-0.3472314167626071,0.39961706105910194,-0.2166706010189041,0.11922012561949845,0.32347952895027443,-0.4785882223380154,-0.1387068069964346,1.0002037240901964,-0.42594849699032294,0.576325735394843,0.9011180973452062,0.776705446342711,0.0935596600019327
| 3,425
|
Abnormal glomerular mesangium morphology
| 6
| 23
| 2.12933
| 0.033227
|
Q8N1F7,Q14C86,Q96D53,P00813,P60033,O95470
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
385,231,136,14,272,367
|
1172,367,14,2632,2139,1609,1103,272,1149,1564,231,1982,999,385,3168,2699,1742,136,2310,1524,2517,514,1758
|
0.14485178548258162,0.9754688945658373,4.748071870065068,-0.5842626139461844,-0.3210563089295906,-0.0610168199068948,0.1960292991597587,1.1972206297942891,0.170454792757679,-0.035180219401076525,1.3683838826407642,-0.24272017828745532,0.2725833089167855,0.950709756463659,-1.012467779172713,-0.6107646440167533,-0.11277994734734909,1.851429702113107,-0.3996773248018237,-0.009373375282462895,-0.5049571593465545,0.7517476513909233,-0.11277994734734909
| 3,425
|
Subsets and Splits
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