term
stringlengths 2
121
| overlap
int64 6
281
| setsize
int64 7
499
| score
float64 1.96
10.6
| pval
float64 0
0.05
| edge
stringlengths 41
1.97k
| type
stringclasses 5
values | subtype
stringclasses 24
values | subtype_key
stringclasses 24
values | edge_idxs
stringlengths 11
1.17k
| ann_idxs
stringlengths 19
2.31k
| ann_vals
stringlengths 124
9.94k
| sig_size
int64 2.2k
3.73k
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Outer mitochondrial membrane protein complex
| 12
| 15
| 3.297358
| 0.000976
|
Q15388,Q6UXV4,Q5XKP0,Q8N4H5,Q9BUR5,O75431,Q9NS69,Q16891,Q13505,O96008,Q9NX63,Q9Y512
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
352,195,132,29,165,357,38,210,52,502,443,323
|
357,1449,502,1475,52,352,210,132,195,29,165,38,542,443,323
|
1.120839071139155,-0.12770013664497198,0.8183900031612562,-0.1404068795755925,3.026879918923703,1.1419450738425903,1.640044944107091,2.141887659699094,1.6986756619645358,3.1073290564690894,1.9095856653720285,3.1073290564690894,0.7518164632462099,0.927934341607611,1.2257336786097104
| 3,120
|
Organophosphate ester transport
| 15
| 26
| 3.297022
| 0.000977
|
P08183,P12236,P41440,Q6NUK1,Q14108,P12235,Q8WTV0,Q8TB61,Q96GC9,Q9H2D1,Q08722,Q9HC21,O43808,Q9NZD2,Q8TDW0
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
190,609,508,390,22,579,101,200,265,36,206,373,529,184,547
|
529,729,190,579,609,2608,870,508,1806,842,2028,206,22,634,390,200,547,101,265,1331,1561,36,373,184,1290,1206
|
0.774079390173673,0.49045228472298324,1.7471650667426148,0.6733223906940821,0.628061558250135,-0.7668105367504043,0.32631335668396794,0.8073390961220606,-0.30783379939432337,0.35000601574553336,-0.4129986202657584,1.6498506656784873,3.1073290564690894,0.6053183644197377,1.04645811026075,1.6791862202916965,0.7406578703701303,2.3757265160314076,1.4309005541628823,-0.05196213624197448,-0.1786726765570447,3.1073290564690894,1.0890591952246833,1.7664679945101098,-0.026905183599894182,0.03533096386757563
| 3,120
|
Endoplasmic reticulum organization
| 24
| 46
| 3.287126
| 0.001012
|
Q8N4V1,Q15363,Q15006,P61026,Q9P2W9,Q9NPA0,Q15041,Q5JRA6,Q8NHH9,Q5J8M3,Q00765,Q12907,Q15629,Q8N5M9,Q9H6H4,O95197,Q9NQC3,O14657,O43765,Q12981,O43681,P57088,P46379,Q96A33
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
30,136,518,516,40,277,279,545,172,689,310,688,314,187,448,60,72,337,584,221,486,488,497,125
|
791,1912,1567,337,1021,1050,2662,486,584,2256,60,928,497,697,488,516,2694,310,688,221,518,279,1810,136,314,689,545,3101,30,187,860,815,172,125,1042,1417,1285,1155,448,893,277,72,2089,1205,1290,40
|
0.40887832137263497,-0.36020808645859054,-0.19147680577398604,1.1839656140069246,0.17025670420391295,0.1459248602176856,-0.8088863866647676,0.8404387020294766,0.6620352061775991,-0.533337616964219,2.879803953814494,0.2667168001795272,0.8294231843173793,0.5251156174631679,0.8404387020294766,0.7962704004189698,-0.8229719076907467,1.2672525814950062,0.5366310104853638,1.5908104250465758,0.7962704004189698,1.3903464678842952,-0.30783379939432337,2.123579621130263,1.2568960359855035,0.5366310104853638,0.7406578703701303,-2.0797011567697794,3.1073290564690894,1.7568231217436605,0.33817003194732587,0.3853906088485544,1.871702741792419,2.187453572170523,0.158101752015416,-0.10235882830439685,-0.026905183599894182,0.07239784971023856,0.9170579238372758,0.314435910199321,1.4005070484783886,2.7717071857086912,-0.43955226841481043,0.03533096386757563,-0.026905183599894182,3.1073290564690894
| 3,120
|
Glycoprotein biosynthetic process
| 18
| 51
| 3.265563
| 0.001092
|
O43505,Q7LGA3,Q10472,O60476,Q99805,Q9BT22,Q9BV10,Q9H6U8,O15118,Q04656,P46977,Q92542,Q96JB2,Q86YN1,Q9H4A6,Q8NCH0,Q96L58,Q11206
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
96,27,163,452,197,135,346,363,141,398,270,174,188,147,214,57,284,191
|
2704,141,2533,96,452,906,1141,2363,1794,1191,2412,487,1425,3097,1360,888,871,270,1839,706,1896,398,2130,1454,707,163,191,1364,1163,667,1148,27,1611,147,57,1181,174,188,284,1120,197,135,346,576,1761,214,363,657,1137,1587,2548
|
-0.837087785495116,2.068372036315107,-0.7111258245859526,2.4022241001142395,0.9061643301278702,0.29061838215713776,0.07239784971023856,-0.6011513795208029,-0.30783379939432337,0.03533096386757563,-0.6284732846345887,0.8404387020294766,-0.11501748631498755,-1.927226968449506,-0.07711309132908688,0.314435910199321,0.32631335668396794,1.4106528917947436,-0.3208887425169809,0.5135807473198399,-0.34707577428405895,1.0143344206282272,-0.46621274973913956,-0.12770013664497198,0.5135807473198399,1.9095856653720285,1.7471650667426148,-0.07711309132908688,0.060064905188923254,0.5710610469198908,0.07239784971023856,3.1073290564690894,-0.20430553885186603,2.022036880868175,2.945536868285547,0.04770930716017372,1.862200304747472,1.7568231217436605,1.369980905900342,0.09699614240690609,1.6889376731850534,2.132739507118012,1.1629871131431153,0.6845910055704713,-0.28180050541945734,1.620392445349469,1.11026194950554,0.582499249500083,0.08470823190970675,-0.19147680577398604,-0.7111258245859526
| 3,120
|
Protein transmembrane transport
| 14
| 24
| 3.247982
| 0.001162
|
Q9UGP8,Q15388,O75381,Q07820,Q9NS69,O95831,Q99442,Q3ZCQ8,P49755,O96008,Q15629,O14925,O60830,O75298
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
477,352,387,219,38,332,431,407,213,502,314,59,4,5
|
59,539,1624,4,5,387,1449,332,502,2153,663,213,2539,1951,2694,219,352,314,407,2169,431,1286,38,477
|
2.912744419090262,0.7518164632462099,-0.21715898005436454,3.1073290564690894,3.1073290564690894,1.04645811026075,-0.12770013664497198,1.1944311691364766,0.8183900031612562,-0.4795833493036897,0.5710610469198908,1.6302255513335107,-0.7111258245859526,-0.37336641310163715,-0.8229719076907467,1.6006849247164414,1.1419450738425903,1.2568960359855035,0.9928354619075869,-0.4795833493036897,0.9387936429122186,-0.026905183599894182,3.1073290564690894,0.8624169951839001
| 3,120
|
Muscle abnormality related to mitochondrial dysfunction
| 11
| 37
| 3.244218
| 0.001178
|
Q86Y39,Q53H12,O60313,Q96CU9,Q9Y6M9,Q9UBX3,O96000,Q9Y2R0,P00846,P00403,Q8IUX1
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
170,171,203,48,80,83,180,45,61,94,223
|
3107,744,203,1770,577,1423,1127,615,180,94,61,1023,579,2199,2071,2237,2984,781,2124,1090,171,170,223,1705,48,1392,1370,1332,2216,245,470,1186,83,45,1595,2389,80
|
-2.3244806247371206,0.45561168292170245,1.6498506656784873,-0.29480442366640136,0.6733223906940821,-0.11501748631498755,0.08470823190970675,0.6166994167264761,1.795323913719972,2.4198350975517866,2.879803953814494,0.17025670420391295,0.6733223906940821,-0.5064058663136635,-0.43955226841481043,-0.5198580262786188,-1.2302452877439438,0.42059180507154753,-0.46621274973913956,0.12150490797103468,1.8811924590596094,1.8906694939515276,1.5809220421218821,-0.2558686053497298,3.067214874831629,-0.08972406297560863,-0.07711309132908688,-0.05196213624197448,-0.5064058663136635,1.5212977725567718,0.8733798938179188,0.04770930716017372,2.559195032678293,3.1073290564690894,-0.19147680577398604,-0.6011513795208029,2.6449491417397626
| 3,120
|
Liposaccharide metabolic process
| 10
| 17
| 3.239541
| 0.001197
|
P06280,P17900,Q99805,Q8NBX0,Q5H8A4,P04066,P16278,Q9NZD2,P06865,Q11206
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
159,68,197,71,233,237,117,184,252,191
|
1794,275,237,159,252,608,117,68,2028,191,233,71,403,817,564,197,184
|
-0.30783379939432337,1.4005070484783886,1.54122881436266,1.9472674467092672,1.4912946822328113,0.628061558250135,2.241752275250984,2.7800795662254263,-0.4129986202657584,1.7471650667426148,1.5611034542199569,2.7717071857086912,1.0035932957279798,0.3853906088485544,0.7070727943770848,1.6889376731850534,1.7664679945101098
| 3,120
|
Organic acid transport
| 25
| 44
| 3.234485
| 0.001219
|
P41440,Q9H936,Q9H9B4,Q9H2D1,Q02978,O43808,Q15041,P23786,P31751,Q8TDW0,P50416,O43772,P08195,O60831,O75746,Q9BQT8,Q96NB2,Q9UJS0,P08183,P30825,P05556,Q9UBX3,Q6P4A7,Q15758,O75915
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
508,777,522,36,784,529,279,155,663,547,161,291,675,551,425,296,686,311,190,76,586,83,356,753,628
|
1398,2040,291,529,551,425,628,1143,1169,2303,1268,586,2630,190,675,1067,2021,2941,155,1069,1428,76,663,918,508,161,920,1106,783,784,279,1810,753,1577,356,547,686,296,36,1787,777,522,83,311
|
-0.10235882830439685,-0.42626214908149684,1.3290708428266285,0.774079390173673,0.7294811048241373,0.9496358869067834,0.6053183644197377,0.07239784971023856,0.04770930716017372,-0.5603795848494529,-0.026905183599894182,0.6620352061775991,-0.7808058429070066,1.7471650667426148,0.5596036536159662,0.13372594148942707,-0.4129986202657584,-1.1260105908189355,1.9940903702899961,0.13372594148942707,-0.11501748631498755,2.704378541877951,0.5710610469198908,0.2786781386912482,0.8073390961220606,1.9472674467092672,0.2786781386912482,0.10926167126011344,0.42059180507154753,0.42059180507154753,1.3903464678842952,-0.30783379939432337,0.45561168292170245,-0.19147680577398604,1.1314000946481249,0.7406578703701303,0.5481269986020768,1.318805766980325,3.1073290564690894,-0.29480442366640136,0.4322851425823638,0.7962704004189698,2.559195032678293,1.2672525814950062
| 3,120
|
Glycerolipid metabolic process
| 20
| 63
| 3.22862
| 0.001244
|
Q9UG56,Q9NPH0,Q9NTJ5,Q9UBV2,Q99623,Q92643,P50416,Q96N66,Q8NF37,Q53H12,Q9BVG9,Q10713,Q9NX62,P35790,O95674,Q9NZC3,Q8WTV0,Q5H8A4,Q8NCG7,Q8NCC3
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
267,37,399,41,146,403,161,290,162,171,176,54,55,194,444,207,101,233,362,120
|
3065,2808,456,1083,1941,1794,2093,1169,444,2939,2780,2044,2415,2972,918,194,1319,1402,3003,1275,161,1970,1130,2724,54,2332,171,233,844,987,1367,794,814,2407,1058,120,362,162,735,101,816,804,403,817,2384,290,623,564,146,1247,864,176,1371,1561,37,399,582,55,2089,207,41,267,766
|
-1.5534479602974562,-0.9367611784117341,0.8952535006860544,0.12150490797103468,-0.37336641310163715,-0.30783379939432337,-0.4528690958405845,0.04770930716017372,0.9170579238372758,-1.1260105908189355,-0.9081276149528227,-0.42626214908149684,-0.6284732846345887,-1.2002923885824353,0.2786781386912482,1.6986756619645358,-0.05196213624197448,-0.10235882830439685,-1.2905705747567982,-0.026905183599894182,1.9472674467092672,-0.38655086787023707,0.08470823190970675,-0.8512341644014038,2.9944511899123603,-0.5739422113824679,1.8811924590596094,1.5611034542199569,0.35000601574553336,0.20659078834565117,-0.07711309132908688,0.40887832137263497,0.3853906088485544,-0.6147981757408897,0.1459248602176856,2.2327310420192736,1.11026194950554,1.9190248758612094,0.4788585457441188,2.3757265160314076,0.3853906088485544,0.3971446149576911,1.0035932957279798,0.3853906088485544,-0.6011513795208029,1.3393208461533432,0.6166994167264761,0.7070727943770848,2.031328055456678,-0.0019414638218673386,0.33817003194732587,1.8526851103515125,-0.07711309132908688,-0.1786726765570447,3.1073290564690894,1.0143344206282272,0.6733223906940821,2.986321497503092,-0.43955226841481043,1.6498506656784873,3.1073290564690894,1.4309005541628823,0.44395840998636554
| 3,120
|
Glycosaminoglycan metabolism
| 10
| 15
| 3.228234
| 0.001246
|
O43505,Q7LGA3,Q8TB61,P16278,P15586,P54802,Q8NCH0,Q96L58,P06865,Q11206
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
96,27,200,117,246,119,57,284,252,191
|
2346,96,252,608,353,246,117,119,191,27,57,200,284,1120,2548
|
-0.5875327673192509,2.4022241001142395,1.4912946822328113,0.628061558250135,1.1314000946481249,1.5113109906247206,2.241752275250984,2.2327310420192736,1.7471650667426148,3.1073290564690894,2.945536868285547,1.6791862202916965,1.369980905900342,0.09699614240690609,-0.7111258245859526
| 3,120
|
Azurophil granule membrane
| 9
| 20
| 3.217909
| 0.001291
|
Q8NF37,P13473,Q07065,Q92542,P42785,O95721,P11279,Q9NZJ7,O15260
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
162,228,20,174,46,204,278,216,285
|
285,1100,728,2588,204,365,278,228,871,46,1721,854,20,957,162,174,2250,576,216,1290
|
1.3597758294429656,0.10926167126011344,0.49045228472298324,-0.7528450205022053,1.6498506656784873,1.0996686756577085,1.3903464678842952,1.5710197329219444,0.32631335668396794,3.083286891375091,-0.2688219354682781,0.33817003194732587,3.1073290564690894,0.24273050882000022,1.9190248758612094,1.862200304747472,-0.5198580262786188,0.6845910055704713,1.6105455839468559,-0.026905183599894182
| 3,120
|
Nonalcoholic fatty liver disease
| 14
| 51
| 3.209885
| 0.001328
|
P13073,P14406,P20674,O95169,Q96GC9,Q86Y39,P22695,Q9P0J0,Q9Y6M9,Q9UDW1,P21912,O96000,O14949,P00403
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
9,10,66,292,265,170,205,143,80,42,178,180,1,94
|
3107,456,744,995,1,2718,1569,1770,577,1423,1127,376,292,1192,2017,180,94,1627,965,561,1256,9,10,293,1145,2199,66,178,205,2071,2157,663,1359,1320,2394,2984,811,2424,1655,1478,1536,3020,1745,1075,1407,170,265,470,143,42,80
|
-2.3244806247371206,0.8952535006860544,0.45561168292170245,0.19450113637357203,3.1073290564690894,-0.8512341644014038,-0.19147680577398604,-0.29480442366640136,0.6733223906940821,-0.11501748631498755,0.08470823190970675,1.0784334535521216,1.3290708428266285,0.03533096386757563,-0.4129986202657584,1.795323913719972,2.4198350975517866,-0.21715898005436454,0.23070539012934577,0.7070727943770848,-0.014411717321070097,3.1073290564690894,3.1073290564690894,1.3290708428266285,0.07239784971023856,-0.5064058663136635,2.7884423176310245,1.8049164509564872,1.6498506656784873,-0.43955226841481043,-0.4795833493036897,0.5710610469198908,-0.07711309132908688,-0.05196213624197448,-0.6147981757408897,-1.2302452877439438,0.3853906088485544,-0.6284732846345887,-0.23003723432961226,-0.1404068795755925,-0.16589304761576545,-1.3514648583892033,-0.28180050541945734,0.13372594148942707,-0.10235882830439685,1.8906694939515276,1.4309005541628823,0.8733798938179188,2.068372036315107,3.1073290564690894,2.6449491417397626
| 3,120
|
Molecular transducer activity
| 18
| 32
| 3.209589
| 0.001329
|
Q99720,Q15375,Q14108,Q8WTV0,Q9Y6I9,Q08722,Q9UBG0,O15118,P11717,P05556,Q99442,P20645,O15031,Q9BUN8,P30536,O75787,Q15629,Q9UGP8
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
35,509,22,101,122,206,208,141,587,586,431,344,614,372,338,501,314,477
|
2147,614,141,501,586,1598,662,587,344,338,3049,1893,2394,1680,206,945,22,509,314,753,831,1178,101,998,431,35,372,1288,2109,208,477,122
|
-0.4795833493036897,0.6166994167264761,2.068372036315107,0.8183900031612562,0.6620352061775991,-0.20430553885186603,0.5710610469198908,0.6620352061775991,1.1629871131431153,1.1839656140069246,-1.4906198916646207,-0.34707577428405895,-0.6147981757408897,-0.2429404073162766,1.6498506656784873,0.2547342844462805,3.1073290564690894,0.8073390961220606,1.2568960359855035,0.45561168292170245,0.3618213873624192,0.04770930716017372,2.3757265160314076,0.19450113637357203,0.9387936429122186,3.1073290564690894,1.0890591952246833,-0.026905183599894182,-0.4528690958405845,1.6498506656784873,0.8624169951839001,2.2236984308409684
| 3,120
|
Slc mediated transmembrane transport
| 16
| 24
| 3.206239
| 0.001345
|
P12236,Q9H936,P12235,P08195,Q70HW3,Q8TB61,P30825,Q15043,Q15758,P35613,Q8TAD4,Q9UBX3,P55011,P05141,Q9Y6M7,Q9NY64
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
609,777,579,675,168,200,76,334,753,145,179,83,783,729,506,189
|
729,675,1067,579,609,1801,76,145,1532,1106,783,334,753,1577,168,179,200,804,1331,1787,777,189,83,506
|
0.49045228472298324,0.5596036536159662,0.13372594148942707,0.6733223906940821,0.628061558250135,-0.30783379939432337,2.704378541877951,2.031328055456678,-0.16589304761576545,0.10926167126011344,0.42059180507154753,1.1944311691364766,0.45561168292170245,-0.19147680577398604,1.9001338837009643,1.8049164509564872,1.6791862202916965,0.3971446149576911,-0.05196213624197448,-0.29480442366640136,0.4322851425823638,1.7568231217436605,2.559195032678293,0.8183900031612562
| 3,120
|
SLC25 family of mitochondrial transporters
| 16
| 19
| 3.202275
| 0.001363
|
P12236,Q9H936,O43772,Q6NUK1,P12235,Q9Y6C9,Q70HW3,O75746,Q9BQT8,Q9H2D1,Q9HC21,Q9UBX3,Q9UJS0,O43808,P05141,Q9NZJ7
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
609,777,291,390,579,227,168,425,296,36,373,83,311,529,729,216
|
291,529,425,729,579,609,920,1072,784,390,168,296,36,777,373,216,83,311,227
|
1.3290708428266285,0.774079390173673,0.9496358869067834,0.49045228472298324,0.6733223906940821,0.628061558250135,0.2786781386912482,0.13372594148942707,0.42059180507154753,1.04645811026075,1.9001338837009643,1.318805766980325,3.1073290564690894,0.4322851425823638,1.0890591952246833,1.6105455839468559,2.559195032678293,1.2672525814950062,1.5809220421218821
| 3,120
|
Mitochondrial carrier domain superfamily [IPR023395]
| 16
| 19
| 3.202275
| 0.001363
|
P12236,Q9H936,O43772,Q6NUK1,P12235,Q9Y6C9,Q70HW3,O75746,Q9BQT8,Q9H2D1,Q9HC21,Q9UBX3,Q9UJS0,O43808,P05141,Q9NZJ7
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
609,777,291,390,579,227,168,425,296,36,373,83,311,529,729,216
|
291,529,425,729,579,609,920,1072,784,390,168,296,36,777,373,216,83,311,227
|
1.3290708428266285,0.774079390173673,0.9496358869067834,0.49045228472298324,0.6733223906940821,0.628061558250135,0.2786781386912482,0.13372594148942707,0.42059180507154753,1.04645811026075,1.9001338837009643,1.318805766980325,3.1073290564690894,0.4322851425823638,1.0890591952246833,1.6105455839468559,2.559195032678293,1.2672525814950062,1.5809220421218821
| 3,120
|
Mitochondrial substrate/solute carrier [IPR018108]
| 16
| 19
| 3.202275
| 0.001363
|
P12236,Q9H936,O43772,Q6NUK1,P12235,Q9Y6C9,Q70HW3,O75746,Q9BQT8,Q9H2D1,Q9HC21,Q9UBX3,Q9UJS0,O43808,P05141,Q9NZJ7
|
Sequence
|
InterPro Repeat
|
interpro_repeat
|
609,777,291,390,579,227,168,425,296,36,373,83,311,529,729,216
|
291,529,425,729,579,609,920,1072,784,390,168,296,36,777,373,216,83,311,227
|
1.3290708428266285,0.774079390173673,0.9496358869067834,0.49045228472298324,0.6733223906940821,0.628061558250135,0.2786781386912482,0.13372594148942707,0.42059180507154753,1.04645811026075,1.9001338837009643,1.318805766980325,3.1073290564690894,0.4322851425823638,1.0890591952246833,1.6105455839468559,2.559195032678293,1.2672525814950062,1.5809220421218821
| 3,120
|
Dementia
| 23
| 61
| 3.200629
| 0.001371
|
Q9Y487,O15118,P04062,P35637,Q14108,Q9UHD9,Q13510,P02792,P21912,P00846,Q9UQN3,P17900,O60313,P35670,Q9NZJ7,P00403,P20700,O43681,Q9NQZ5,P22626,O76024,O96008,P06865
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
130,141,275,405,22,294,21,552,178,61,451,68,203,342,216,94,478,486,234,496,244,502,252
|
1567,141,703,486,203,2588,244,502,94,61,552,1023,275,2553,566,252,1298,2666,68,478,178,496,2847,2157,1718,405,342,741,2047,2646,853,1970,1090,1361,2327,842,2027,1604,684,21,22,1132,2596,1484,680,814,1684,816,2248,2215,776,1392,3045,1435,234,216,835,294,451,1995,130
|
-0.19147680577398604,2.068372036315107,0.5135807473198399,0.8404387020294766,1.6498506656784873,-0.7528450205022053,1.5212977725567718,0.8183900031612562,2.4198350975517866,2.879803953814494,0.7294811048241373,0.17025670420391295,1.4005070484783886,-0.7250028020839093,0.6958411178937519,1.4912946822328113,-0.039421957943272905,-0.8088863866647676,2.7800795662254263,0.8514366183973154,1.8049164509564872,0.8294231843173793,-0.9799484723561187,-0.4795833493036897,-0.2688219354682781,0.9928354619075869,1.1734842794897706,0.4672450365868581,-0.42626214908149684,-0.7948310791463405,0.33817003194732587,-0.38655086787023707,0.12150490797103468,-0.07711309132908688,-0.5739422113824679,0.35000601574553336,-0.4129986202657584,-0.20430553885186603,0.5481269986020768,3.1073290564690894,3.1073290564690894,0.08470823190970675,-0.7528450205022053,-0.1404068795755925,0.5596036536159662,0.3853906088485544,-0.2429404073162766,0.3853906088485544,-0.5198580262786188,-0.5064058663136635,0.4322851425823638,-0.08972406297560863,-1.4594351482439722,-0.11501748631498755,1.5611034542199569,1.6105455839468559,0.3618213873624192,1.3290708428266285,0.9170579238372758,-0.38655086787023707,2.1510241118925633
| 3,120
|
Exocytic vesicle
| 15
| 42
| 3.185028
| 0.001447
|
Q9BT78,O15400,Q96A57,P20020,P50897,Q9GZY8,Q92542,O60499,O43760,O76024,P11279,P51790,Q15907,Q9UI14,Q9NY64
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
230,134,102,388,16,336,174,81,211,244,278,369,23,154,189
|
1567,884,2040,727,134,434,211,81,244,964,1035,1529,278,388,1193,1010,1300,2954,16,954,2989,369,2026,733,516,1871,1323,567,2576,1133,956,2211,23,719,174,1643,102,230,624,336,189,154
|
-0.19147680577398604,0.314435910199321,-0.42626214908149684,0.49045228472298324,2.132739507118012,0.927934341607611,1.6302255513335107,2.602199126779496,1.5212977725567718,0.23070539012934577,0.158101752015416,-0.16589304761576545,1.3903464678842952,1.04645811026075,0.03533096386757563,0.1823898035706314,-0.039421957943272905,-1.1704774288251414,3.1073290564690894,0.24273050882000022,-1.2452739049804467,1.0890591952246833,-0.4129986202657584,0.4788585457441188,0.7962704004189698,-0.3339693636833012,-0.05196213624197448,0.6958411178937519,-0.7389091550000886,0.08470823190970675,0.24273050882000022,-0.5064058663136635,3.1073290564690894,0.5020263274235438,1.862200304747472,-0.21715898005436454,2.3668722474661834,1.5710197329219444,0.6166994167264761,1.1944311691364766,1.7568231217436605,2.003418073325324
| 3,120
|
Late endosome
| 22
| 64
| 3.167396
| 0.001538
|
Q8IY95,O15400,O15118,Q04656,P11279,O95772,Q14108,Q9Y3E7,Q8IZ07,Q9UQN3,Q9BRK5,Q15043,P11717,P35670,Q9NZJ7,P20645,Q96A57,P13473,Q8IV08,Q9P253,Q9BUN8,P51790
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
391,134,141,398,278,7,22,559,177,451,593,334,587,342,216,344,102,228,106,375,372,369
|
2039,925,141,134,1189,1357,7,1862,2152,1450,1628,278,587,228,2261,344,740,1383,342,2419,2646,954,369,854,823,1747,2651,398,684,22,334,1409,2485,957,106,391,177,3058,102,2104,960,2215,992,1262,593,372,1203,736,1184,2086,1438,598,725,895,216,1353,375,2360,1963,807,451,1493,559,1446
|
-0.42626214908149684,0.2667168001795272,2.068372036315107,2.132739507118012,0.03533096386757563,-0.07711309132908688,3.1073290564690894,-0.3339693636833012,-0.4795833493036897,-0.12770013664497198,-0.21715898005436454,1.3903464678842952,0.6620352061775991,1.5710197329219444,-0.533337616964219,1.1629871131431153,0.4672450365868581,-0.08972406297560863,1.1734842794897706,-0.6284732846345887,-0.7948310791463405,0.24273050882000022,1.0890591952246833,0.33817003194732587,0.3736162256132579,-0.28180050541945734,-0.7948310791463405,1.0143344206282272,0.5481269986020768,3.1073290564690894,1.1944311691364766,-0.10235882830439685,-0.6696697876094331,0.24273050882000022,2.34913092241935,1.04645811026075,1.8336162983534876,-1.5062692780273925,2.3668722474661834,-0.4528690958405845,0.24273050882000022,-0.5064058663136635,0.20659078834565117,-0.014411717321070097,0.6620352061775991,1.0890591952246833,0.03533096386757563,0.4788585457441188,0.04770930716017372,-0.43955226841481043,-0.11501748631498755,0.6507293845573393,0.5020263274235438,0.314435910199321,1.6105455839468559,-0.06452581499784397,1.0890591952246833,-0.5875327673192509,-0.37336641310163715,0.3971446149576911,0.9170579238372758,-0.1404068795755925,0.7182861013625904,-0.11501748631498755
| 3,120
|
Respiratory chain
| 12
| 34
| 3.163715
| 0.001558
|
O95169,P14927,Q86Y39,P22695,Q9P0J0,Q96CU9,Q9Y6M9,Q9UDW1,O96000,O14949,O95168,P00403
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
292,293,170,205,143,48,80,42,180,1,376,94
|
3107,744,1,2718,1569,1770,577,1423,1127,376,292,1192,2017,180,94,1023,965,293,2199,205,2071,1359,1320,2984,1655,1075,1407,383,170,48,470,143,42,80
|
-2.3244806247371206,0.45561168292170245,3.1073290564690894,-0.8512341644014038,-0.19147680577398604,-0.29480442366640136,0.6733223906940821,-0.11501748631498755,0.08470823190970675,1.0784334535521216,1.3290708428266285,0.03533096386757563,-0.4129986202657584,1.795323913719972,2.4198350975517866,0.17025670420391295,0.23070539012934577,1.3290708428266285,-0.5064058663136635,1.6498506656784873,-0.43955226841481043,-0.07711309132908688,-0.05196213624197448,-1.2302452877439438,-0.23003723432961226,0.13372594148942707,-0.10235882830439685,1.0677913957002723,1.8906694939515276,3.067214874831629,0.8733798938179188,2.068372036315107,3.1073290564690894,2.6449491417397626
| 3,120
|
Aminoglycan metabolic process
| 11
| 16
| 3.144267
| 0.001665
|
O43505,Q7LGA3,P04066,P16278,P15586,P54802,Q9NX62,Q8NCH0,Q96L58,P06865,Q11206
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
96,27,237,117,246,119,55,57,284,252,191
|
96,2363,2921,237,252,608,353,246,117,119,2812,191,27,57,284,55
|
2.4022241001142395,-0.6011513795208029,-1.081846393052922,1.54122881436266,1.4912946822328113,0.628061558250135,1.1314000946481249,1.5113109906247206,2.241752275250984,2.2327310420192736,-0.9367611784117341,1.7471650667426148,3.1073290564690894,2.945536868285547,1.369980905900342,2.986321497503092
| 3,120
|
Mitochondrial biogenesis
| 12
| 35
| 3.136463
| 0.00171
|
Q6UXV4,Q5XKP0,Q9BUR5,P24539,O75431,Q16891,P56385,Q13505,Q9NX63,P00846,O75964,Q9Y512
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
195,132,165,12,357,210,348,52,443,61,6,323
|
1596,2112,357,660,6,1161,61,1887,458,12,1273,801,1475,1999,2122,2723,1478,1536,1479,348,1363,1025,52,2619,1346,210,132,195,1902,3023,1392,165,542,443,323
|
-0.20430553885186603,-0.46621274973913956,1.120839071139155,0.5710610469198908,3.1073290564690894,0.060064905188923254,2.879803953814494,-0.34707577428405895,0.8952535006860544,3.1073290564690894,-0.026905183599894182,0.3971446149576911,-0.1404068795755925,-0.3997615651907241,-0.46621274973913956,-0.8512341644014038,-0.1404068795755925,-0.16589304761576545,-0.1404068795755925,1.1524740622552163,-0.07711309132908688,0.17025670420391295,3.026879918923703,-0.7668105367504043,-0.06452581499784397,1.640044944107091,2.141887659699094,1.6986756619645358,-0.34707577428405895,-1.3514648583892033,-0.08972406297560863,1.9095856653720285,0.7518164632462099,0.927934341607611,1.2257336786097104
| 3,120
|
Lytic vacuole organization
| 13
| 24
| 3.135309
| 0.001717
|
O14773,P11117,O75503,Q14108,Q9BZG1,P50897,Q9Y3E7,P10253,Q9P253,P04062,O75787,P54802,Q9UQN3
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
0,8,64,22,392,16,559,365,375,275,501,119,451
|
2512,0,64,501,964,275,608,365,8,1998,16,954,119,823,22,957,922,2104,2215,392,895,375,451,559
|
-0.6972780863213089,3.1073290564690894,2.8632777541578998,0.8183900031612562,0.23070539012934577,1.4005070484783886,0.628061558250135,1.0996686756577085,3.1073290564690894,-0.3997615651907241,3.1073290564690894,0.24273050882000022,2.2327310420192736,0.3736162256132579,3.1073290564690894,0.24273050882000022,0.2786781386912482,-0.4528690958405845,-0.5064058663136635,1.04645811026075,0.314435910199321,1.0890591952246833,0.9170579238372758,0.7182861013625904
| 3,120
|
Metal ion transmembrane transporter activity
| 18
| 28
| 3.132893
| 0.001731
|
P05026,P16615,P98194,Q9H0U3,Q8N4V1,P20020,P05023,Q9UM00,Q15043,Q04656,P23634,Q6P4Q7,Q8TAD4,Q9HD20,Q9Y6M7,P35670,O95202,Q8NE86
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
661,160,289,576,30,388,201,396,334,398,430,465,179,149,506,342,282,481
|
282,201,661,1598,1862,2152,675,160,388,430,342,783,2694,289,2801,398,334,465,30,481,179,998,1081,576,1787,149,396,506
|
1.369980905900342,1.6596427578574324,0.5710610469198908,-0.20430553885186603,-0.3339693636833012,-0.4795833493036897,0.5596036536159662,1.9472674467092672,1.04645811026075,0.9387936429122186,1.1734842794897706,0.42059180507154753,-0.8229719076907467,1.3393208461533432,-0.9224287018087298,1.0143344206282272,1.1944311691364766,0.8843253753961765,3.1073290564690894,0.8514366183973154,1.8049164509564872,0.19450113637357203,0.13372594148942707,0.6845910055704713,-0.29480442366640136,2.022036880868175,1.0250588936033453,0.8183900031612562
| 3,120
|
Carboxylic acid transport
| 19
| 32
| 3.112486
| 0.001855
|
P41440,Q9H936,Q9H9B4,Q9H2D1,Q02978,Q15041,Q8TDW0,P08195,O60831,O75746,Q9BQT8,Q96NB2,Q9UJS0,P30825,P05556,Q9UBX3,Q9NZJ7,Q15758,O75915
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
508,777,522,36,784,279,547,675,551,425,296,686,311,76,586,83,216,753,628
|
1398,2040,551,425,628,1143,1268,586,675,2021,2941,1069,76,508,920,1106,783,784,279,1810,753,1577,547,686,296,36,1787,777,522,216,83,311
|
-0.10235882830439685,-0.42626214908149684,0.7294811048241373,0.9496358869067834,0.6053183644197377,0.07239784971023856,-0.026905183599894182,0.6620352061775991,0.5596036536159662,-0.4129986202657584,-1.1260105908189355,0.13372594148942707,2.704378541877951,0.8073390961220606,0.2786781386912482,0.10926167126011344,0.42059180507154753,0.42059180507154753,1.3903464678842952,-0.30783379939432337,0.45561168292170245,-0.19147680577398604,0.7406578703701303,0.5481269986020768,1.318805766980325,3.1073290564690894,-0.29480442366640136,0.4322851425823638,0.7962704004189698,1.6105455839468559,2.559195032678293,1.2672525814950062
| 3,120
|
Alpha/Beta hydrolase fold [IPR029058]
| 11
| 25
| 3.109519
| 0.001874
|
Q9UMR5,Q9NUJ1,Q9H3G5,P38571,Q9H6V9,P50897,P42785,P07099,Q9HB40,Q8NCC3,P10619
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
98,133,70,229,74,16,46,302,50,120,91
|
2567,2093,302,91,2934,2043,229,46,2421,2394,16,569,1725,774,2407,120,362,2355,70,74,50,133,2510,98,2319
|
-0.7389091550000886,-0.4528690958405845,1.2879196145694298,2.4374031190390943,-1.1112557890025987,-0.42626214908149684,1.5710197329219444,3.083286891375091,-0.6284732846345887,-0.6147981757408897,3.1073290564690894,0.6958411178937519,-0.2688219354682781,0.4322851425823638,-0.6147981757408897,2.2327310420192736,1.11026194950554,-0.5875327673192509,2.7800795662254263,2.7633251516522725,3.034964700499758,2.141887659699094,-0.6834594520783637,2.4022241001142395,-0.5603795848494529
| 3,120
|
Electron transport
| 18
| 47
| 3.097634
| 0.001951
|
Q9H3N1,O95169,P14927,Q86Y39,P22695,Q9P0J0,Q96CU9,Q9Y6M9,Q9UDW1,Q9H1E5,P21912,O96000,Q9NX14,O14949,O95168,O43169,P00403,Q6DKK2
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
483,292,293,170,205,143,48,80,42,148,178,180,470,1,376,2,94,383
|
3107,744,1,2,638,2718,1569,1770,577,1423,1127,376,292,1192,2017,951,180,94,1023,965,2391,293,2199,178,2392,205,2071,2157,1359,2236,1320,2984,1655,519,1075,1407,2403,383,170,48,636,148,483,470,143,42,80
|
-2.3244806247371206,0.45561168292170245,3.1073290564690894,3.1073290564690894,0.593918331939264,-0.8512341644014038,-0.19147680577398604,-0.29480442366640136,0.6733223906940821,-0.11501748631498755,0.08470823190970675,1.0784334535521216,1.3290708428266285,0.03533096386757563,-0.4129986202657584,0.24273050882000022,1.795323913719972,2.4198350975517866,0.17025670420391295,0.23070539012934577,-0.6147981757408897,1.3290708428266285,-0.5064058663136635,1.8049164509564872,-0.6147981757408897,1.6498506656784873,-0.43955226841481043,-0.4795833493036897,-0.07711309132908688,-0.5198580262786188,-0.05196213624197448,-1.2302452877439438,-0.23003723432961226,0.7962704004189698,0.13372594148942707,-0.10235882830439685,-0.6147981757408897,1.0677913957002723,1.8906694939515276,3.067214874831629,0.6053183644197377,2.022036880868175,0.8514366183973154,0.8733798938179188,2.068372036315107,3.1073290564690894,2.6449491417397626
| 3,120
|
Primary mitochondrial disease
| 28
| 97
| 3.095487
| 0.001965
|
Q5XKP0,Q9P0J0,Q9Y2R0,O75880,O14949,Q7KZN9,P13073,O95169,P14927,Q70HW3,Q9BQT8,Q86Y39,Q53H12,Q96CU9,Q96IX5,P00846,P20674,P22695,O60313,Q9Y6M9,O95831,Q9UBX3,O43819,P00403,Q8IUX1,Q6P4A7,Q9Y276,Q9NPL8
|
Drugs and Diseases
|
Protein Atlas Disease involvement
|
protein_atlas_disease_involvement
|
132,143,45,273,1,151,9,292,293,168,296,170,171,48,315,61,66,205,203,80,332,83,217,94,223,356,241,245
|
3107,744,1,2718,2513,217,203,1770,577,1423,1127,1470,273,292,2017,332,94,61,1023,1997,965,2304,579,9,293,2199,66,205,1273,2071,2157,2237,2480,1320,2571,2984,781,855,2124,1090,1107,2398,1363,856,1407,171,2464,2596,1751,1662,132,383,356,168,151,2007,170,1180,223,2959,546,1705,1580,48,504,315,1351,1392,1079,2773,1687,296,1370,493,968,993,1043,2829,694,245,637,470,1709,1186,143,1990,83,2660,241,1650,45,1375,1595,1620,1265,2389,80
|
-2.3244806247371206,0.45561168292170245,3.1073290564690894,-0.8512341644014038,-0.6972780863213089,1.6006849247164414,1.6498506656784873,-0.29480442366640136,0.6733223906940821,-0.11501748631498755,0.08470823190970675,-0.1404068795755925,1.4005070484783886,1.3290708428266285,-0.4129986202657584,1.1944311691364766,2.4198350975517866,2.879803953814494,0.17025670420391295,-0.3997615651907241,0.23070539012934577,-0.5603795848494529,0.6733223906940821,3.1073290564690894,1.3290708428266285,-0.5064058663136635,2.7884423176310245,1.6498506656784873,-0.026905183599894182,-0.43955226841481043,-0.4795833493036897,-0.5198580262786188,-0.6696697876094331,-0.05196213624197448,-0.7389091550000886,-1.2302452877439438,0.42059180507154753,0.33817003194732587,-0.46621274973913956,0.12150490797103468,0.10926167126011344,-0.6147981757408897,-0.07711309132908688,0.33817003194732587,-0.10235882830439685,1.8811924590596094,-0.6559089596214692,-0.7528450205022053,-0.28180050541945734,-0.23003723432961226,2.141887659699094,1.0677913957002723,1.1314000946481249,1.9001338837009643,2.003418073325324,-0.3997615651907241,1.8906694939515276,0.04770930716017372,1.5809220421218821,-1.1704774288251414,0.7406578703701303,-0.2558686053497298,-0.19147680577398604,3.067214874831629,0.8183900031612562,1.236136635275694,-0.06452581499784397,-0.08972406297560863,0.13372594148942707,-0.8938577669791549,-0.2429404073162766,1.318805766980325,-0.07711309132908688,0.8404387020294766,0.23070539012934577,0.20659078834565117,0.158101752015416,-0.9511251967557256,0.5366310104853638,1.5212977725567718,0.6053183644197377,0.8733798938179188,-0.2558686053497298,0.04770930716017372,2.068372036315107,-0.38655086787023707,2.559195032678293,-0.7948310791463405,1.54122881436266,-0.21715898005436454,3.1073290564690894,-0.07711309132908688,-0.19147680577398604,-0.20430553885186603,-0.014411717321070097,-0.6011513795208029,2.6449491417397626
| 3,120
|
Horizontal nystagmus
| 8
| 22
| 3.079346
| 0.002075
|
O14773,Q9H061,Q9NW15,O95831,O60313,P04062,Q9NZJ7,P00846
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
0,65,258,332,203,275,216,61
|
2512,1567,0,1793,203,331,332,61,275,478,966,855,1361,1895,2243,1543,816,65,1692,258,216,1735
|
-0.6972780863213089,-0.19147680577398604,3.1073290564690894,-0.30783379939432337,1.6498506656784873,1.1944311691364766,1.1944311691364766,2.879803953814494,1.4005070484783886,0.8514366183973154,0.23070539012934577,0.33817003194732587,-0.07711309132908688,-0.34707577428405895,-0.5198580262786188,-0.16589304761576545,0.3853906088485544,2.8134730400382506,-0.2429404073162766,1.4712210819843028,1.6105455839468559,-0.2688219354682781
| 3,120
|
Organic acid transmembrane transporter activity
| 13
| 20
| 3.075991
| 0.002098
|
P08183,P41440,Q9H936,P08195,Q9H9B4,Q9BQT8,O75746,Q9H2D1,P30825,Q96NB2,Q15758,Q9UBX3,Q9UJS0
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
190,508,777,675,522,296,425,36,76,686,753,83,311
|
1398,425,1143,190,675,76,508,920,1106,784,753,1577,686,296,36,1787,777,522,83,311
|
-0.10235882830439685,0.9496358869067834,0.07239784971023856,1.7471650667426148,0.5596036536159662,2.704378541877951,0.8073390961220606,0.2786781386912482,0.10926167126011344,0.42059180507154753,0.45561168292170245,-0.19147680577398604,0.5481269986020768,1.318805766980325,3.1073290564690894,-0.29480442366640136,0.4322851425823638,0.7962704004189698,2.559195032678293,1.2672525814950062
| 3,120
|
Nuclear inner membrane
| 15
| 22
| 3.056389
| 0.00224
|
Q8IXM6,Q99720,P20700,O75844,Q5JTV8,O94901,Q03252,Q9H1E5,Q5SNT2,Q9Y2U8,Q9UH99,Q8NC56,Q14728,Q9BTV4,P50402
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
224,35,478,90,590,524,526,148,307,308,471,441,538,475,156
|
90,524,478,2237,853,156,2443,610,526,761,538,708,590,307,224,441,2384,35,475,148,471,308
|
2.4374031190390943,0.7851838529268446,0.8514366183973154,-0.5198580262786188,0.33817003194732587,1.9940903702899961,-0.642176835766896,0.628061558250135,0.7851838529268446,0.44395840998636554,0.7629569483379726,0.5135807473198399,0.6620352061775991,1.2775937576578875,1.5809220421218821,0.927934341607611,-0.6011513795208029,3.1073290564690894,0.8624169951839001,2.022036880868175,0.8733798938179188,1.2775937576578875
| 3,120
|
Nadh dehydrogenase complex assembly
| 10
| 28
| 3.053637
| 0.002261
|
Q9H061,O95169,Q86Y39,Q15070,Q9Y276,Q9P0J0,Q96CU9,Q9Y6M9,O96000,Q8IUX1
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
65,292,170,77,241,143,48,80,180,223
|
3107,2718,1569,1770,577,1127,376,292,2017,180,1023,2071,1655,77,1075,1407,1029,170,223,48,1370,65,1043,470,1186,143,241,80
|
-2.3244806247371206,-0.8512341644014038,-0.19147680577398604,-0.29480442366640136,0.6733223906940821,0.08470823190970675,1.0784334535521216,1.3290708428266285,-0.4129986202657584,1.795323913719972,0.17025670420391295,-0.43955226841481043,-0.23003723432961226,2.695918388459061,0.13372594148942707,-0.10235882830439685,0.17025670420391295,1.8906694939515276,1.5809220421218821,3.067214874831629,-0.07711309132908688,2.8134730400382506,0.158101752015416,0.8733798938179188,0.04770930716017372,2.068372036315107,1.54122881436266,2.6449491417397626
| 3,120
|
Glycosphingolipid metabolism
| 8
| 15
| 3.048144
| 0.002303
|
P06280,P17900,Q13510,P16278,Q9NZJ7,Q9NZD2,P10619,P06865
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
159,68,21,117,216,184,91,252
|
791,486,275,159,252,608,91,117,68,21,597,1042,2089,184,216
|
0.40887832137263497,0.8404387020294766,1.4005070484783886,1.9472674467092672,1.4912946822328113,0.628061558250135,2.4374031190390943,2.241752275250984,2.7800795662254263,3.1073290564690894,0.6507293845573393,0.158101752015416,-0.43955226841481043,1.7664679945101098,1.6105455839468559
| 3,120
|
Alcohol binding
| 7
| 16
| 3.044869
| 0.002328
|
Q14108,P45880,O15118,O94905,P30536,P21796,O95772
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
22,15,141,331,338,11,7
|
1083,141,1794,424,331,7,2152,11,870,1428,338,888,15,842,22,1561
|
0.12150490797103468,2.068372036315107,-0.30783379939432337,0.9496358869067834,1.1944311691364766,3.1073290564690894,-0.4795833493036897,3.1073290564690894,0.32631335668396794,-0.11501748631498755,1.1839656140069246,0.314435910199321,3.1073290564690894,0.35000601574553336,3.1073290564690894,-0.1786726765570447
| 3,120
|
Abnormal activity of mitochondrial respiratory chain
| 13
| 54
| 3.044519
| 0.002331
|
P13073,P20674,Q70HW3,Q86Y39,Q9P0J0,Q96CU9,Q9Y6M9,P21912,Q9UBX3,O96000,Q9Y2R0,Q7KZN9,Q8IUX1
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
9,66,168,170,143,48,80,178,83,180,45,151,223
|
3107,744,2718,2513,1770,577,1423,1127,615,2017,180,1997,9,2199,66,178,2071,2859,2157,2237,2480,2984,1655,855,2124,1701,2696,1407,407,2464,1662,168,151,170,223,1580,48,1616,1351,1370,993,2216,1043,694,245,470,1186,143,1990,83,45,1265,2343,80
|
-2.3244806247371206,0.45561168292170245,-0.8512341644014038,-0.6972780863213089,-0.29480442366640136,0.6733223906940821,-0.11501748631498755,0.08470823190970675,0.6166994167264761,-0.4129986202657584,1.795323913719972,-0.3997615651907241,3.1073290564690894,-0.5064058663136635,2.7884423176310245,1.8049164509564872,-0.43955226841481043,-0.9944080393492227,-0.4795833493036897,-0.5198580262786188,-0.6696697876094331,-1.2302452877439438,-0.23003723432961226,0.33817003194732587,-0.46621274973913956,-0.2558686053497298,-0.8229719076907467,-0.10235882830439685,0.9928354619075869,-0.6559089596214692,-0.23003723432961226,1.9001338837009643,2.003418073325324,1.8906694939515276,1.5809220421218821,-0.19147680577398604,3.067214874831629,-0.20430553885186603,-0.06452581499784397,-0.07711309132908688,0.20659078834565117,-0.5064058663136635,0.158101752015416,0.5366310104853638,1.5212977725567718,0.8733798938179188,0.04770930716017372,2.068372036315107,-0.38655086787023707,2.559195032678293,3.1073290564690894,-0.014411717321070097,-0.5739422113824679,2.6449491417397626
| 3,120
|
Glycerolipid biosynthetic process
| 17
| 42
| 3.042261
| 0.002348
|
Q96N66,Q8NF37,Q9NUQ2,O95674,P35790,Q8WTV0,Q9UG56,Q5H8A4,O00459,Q9NPH0,Q9NTJ5,Q9BVG9,Q92643,Q96S52,Q10713,Q9NX62,Q8NCC3
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
290,162,582,444,194,101,267,233,456,37,399,176,403,564,54,55,120
|
2808,456,1083,1941,1794,1169,444,2939,2780,2044,918,194,1402,1275,1130,54,2332,233,844,987,1367,794,120,162,735,101,816,804,403,817,290,623,564,1247,864,176,1371,37,399,582,55,267
|
-0.9367611784117341,0.8952535006860544,0.12150490797103468,-0.37336641310163715,-0.30783379939432337,0.04770930716017372,0.9170579238372758,-1.1260105908189355,-0.9081276149528227,-0.42626214908149684,0.2786781386912482,1.6986756619645358,-0.10235882830439685,-0.026905183599894182,0.08470823190970675,2.9944511899123603,-0.5739422113824679,1.5611034542199569,0.35000601574553336,0.20659078834565117,-0.07711309132908688,0.40887832137263497,2.2327310420192736,1.9190248758612094,0.4788585457441188,2.3757265160314076,0.3853906088485544,0.3971446149576911,1.0035932957279798,0.3853906088485544,1.3393208461533432,0.6166994167264761,0.7070727943770848,-0.0019414638218673386,0.33817003194732587,1.8526851103515125,-0.07711309132908688,3.1073290564690894,1.0143344206282272,0.6733223906940821,2.986321497503092,1.4309005541628823
| 3,120
|
Hepatic failure
| 14
| 48
| 3.04184
| 0.002351
|
P09622,O43772,P22830,O75381,Q13510,O75845,P38571,O15118,P04062,Q10713,P35670,P23786,P00846,P50416
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
354,291,69,387,21,347,229,141,275,54,342,155,61,161
|
1447,141,291,1624,2742,387,615,347,1054,61,731,1023,275,1571,1673,965,354,1799,69,155,1069,2479,342,229,436,1319,2892,161,1090,2328,1363,54,2074,21,2332,618,718,1977,1351,2035,1043,1062,2037,1824,1467,2066,1375,2703
|
-0.12770013664497198,2.068372036315107,1.3290708428266285,-0.21715898005436454,-0.8796190081405505,1.04645811026075,0.6166994167264761,1.1524740622552163,0.1459248602176856,2.879803953814494,0.4788585457441188,0.17025670420391295,1.4005070484783886,-0.19147680577398604,-0.2429404073162766,0.23070539012934577,1.1314000946481249,-0.30783379939432337,2.7800795662254263,1.9940903702899961,0.13372594148942707,-0.6696697876094331,1.1734842794897706,1.5710197329219444,0.927934341607611,-0.05196213624197448,-1.0379803402121284,1.9472674467092672,0.12150490797103468,-0.5739422113824679,-0.07711309132908688,2.9944511899123603,-0.43955226841481043,3.1073290564690894,-0.5739422113824679,0.6166994167264761,0.5020263274235438,-0.38655086787023707,-0.06452581499784397,-0.4129986202657584,0.158101752015416,0.1459248602176856,-0.4129986202657584,-0.30783379939432337,-0.12770013664497198,-0.42626214908149684,-0.07711309132908688,-0.8229719076907467
| 3,120
|
Diseases of glycosylation
| 9
| 18
| 3.040881
| 0.002359
|
O43505,Q9BT22,Q9H6U8,P16278,Q96L58,Q9BV10,P10619,P06865,Q8NCH0
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
96,135,363,117,284,346,91,252,57
|
96,1794,1191,252,608,91,117,2479,2370,2519,2130,1364,370,57,284,135,346,363
|
2.4022241001142395,-0.30783379939432337,0.03533096386757563,1.4912946822328113,0.628061558250135,2.4374031190390943,2.241752275250984,-0.6696697876094331,-0.6011513795208029,-0.6972780863213089,-0.46621274973913956,-0.07711309132908688,1.0890591952246833,2.945536868285547,1.369980905900342,2.132739507118012,1.1629871131431153,1.11026194950554
| 3,120
|
Carbohydrate derivative transport
| 12
| 16
| 3.038338
| 0.002379
|
P41440,P12235,Q6NUK1,Q8WTV0,Q8TB61,Q08722,L0R6Q1,Q9HC21,O43808,Q9NZD2,Q9NZJ7,Q8TDW0
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
508,579,390,101,200,206,330,373,529,184,216,547
|
330,529,729,579,609,508,842,206,390,200,547,101,1331,373,184,216
|
1.1944311691364766,0.774079390173673,0.49045228472298324,0.6733223906940821,0.628061558250135,0.8073390961220606,0.35000601574553336,1.6498506656784873,1.04645811026075,1.6791862202916965,0.7406578703701303,2.3757265160314076,-0.05196213624197448,1.0890591952246833,1.7664679945101098,1.6105455839468559
| 3,120
|
Corneal opacity
| 23
| 55
| 3.035118
| 0.002404
|
Q6NUK1,O75381,Q16625,Q06136,P04062,O95202,P06280,Q13510,P51648,P40855,Q15645,P35670,Q9NX14,O75844,P10619,O75845,O43505,P08236,Q9NVI7,Q5H8A4,P04066,Q14118,P16278
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
390,387,268,401,275,282,159,21,17,436,446,342,470,90,91,347,96,353,231,233,237,370,117
|
2222,2691,96,2436,2692,1624,899,2920,387,659,90,347,2779,282,556,560,275,237,159,353,2933,91,117,2858,2117,2158,342,436,17,2574,1171,1361,2050,1130,1633,401,2502,21,370,1057,446,2638,268,233,390,2295,2958,657,231,470,1588,2820,1592,484,1125
|
-0.5198580262786188,-0.8229719076907467,2.4022241001142395,-0.642176835766896,-0.8229719076907467,-0.21715898005436454,0.30253761226112147,-1.081846393052922,1.04645811026075,0.5710610469198908,2.4374031190390943,1.1524740622552163,-0.9081276149528227,1.369980905900342,0.7182861013625904,0.7070727943770848,1.4005070484783886,1.54122881436266,1.9472674467092672,1.1314000946481249,-1.1112557890025987,2.4374031190390943,2.241752275250984,-0.9944080393492227,-0.46621274973913956,-0.4795833493036897,1.1734842794897706,0.927934341607611,3.1073290564690894,-0.7389091550000886,0.04770930716017372,-0.07711309132908688,-0.42626214908149684,0.08470823190970675,-0.21715898005436454,1.0035932957279798,-0.6834594520783637,3.1073290564690894,1.0890591952246833,0.1459248602176856,0.9170579238372758,-0.7808058429070066,1.4207840447832099,1.5611034542199569,1.04645811026075,-0.5468447617435744,-1.1704774288251414,0.582499249500083,1.5710197329219444,0.8733798938179188,-0.19147680577398604,-0.9367611784117341,-0.19147680577398604,0.8514366183973154,0.09699614240690609
| 3,120
|
Abnormality of hepatobiliary system physiology
| 21
| 79
| 3.029694
| 0.002448
|
Q5XKP0,Q9BT22,Q16625,O15118,P04062,P23786,P50416,O43772,O95169,Q13510,Q10713,P00846,P22830,P22695,P35670,O43819,O75845,P09622,P38571,Q9Y276,Q96A33
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
132,135,268,141,275,155,161,291,292,21,54,61,69,205,342,217,347,354,229,241,125
|
1447,141,2513,291,217,1624,2742,577,387,615,501,347,292,1054,61,731,1023,275,1571,1673,965,354,2834,1799,205,69,155,1069,2479,342,2891,2746,229,871,436,1319,2892,2237,161,1656,1090,2328,1321,1679,706,1363,54,2074,21,1875,1575,268,2332,618,132,718,1977,2007,1181,1705,125,1351,135,1370,2035,993,1043,1062,2037,1788,637,1824,1467,2066,2932,241,1375,1265,2703
|
-0.12770013664497198,2.068372036315107,-0.6972780863213089,1.3290708428266285,1.6006849247164414,-0.21715898005436454,-0.8796190081405505,0.6733223906940821,1.04645811026075,0.6166994167264761,0.8183900031612562,1.1524740622552163,1.3290708428266285,0.1459248602176856,2.879803953814494,0.4788585457441188,0.17025670420391295,1.4005070484783886,-0.19147680577398604,-0.2429404073162766,0.23070539012934577,1.1314000946481249,-0.9655209099750421,-0.30783379939432337,1.6498506656784873,2.7800795662254263,1.9940903702899961,0.13372594148942707,-0.6696697876094331,1.1734842794897706,-1.0379803402121284,-0.8796190081405505,1.5710197329219444,0.32631335668396794,0.927934341607611,-0.05196213624197448,-1.0379803402121284,-0.5198580262786188,1.9472674467092672,-0.23003723432961226,0.12150490797103468,-0.5739422113824679,-0.05196213624197448,-0.2429404073162766,0.5135807473198399,-0.07711309132908688,2.9944511899123603,-0.43955226841481043,3.1073290564690894,-0.3339693636833012,-0.19147680577398604,1.4207840447832099,-0.5739422113824679,0.6166994167264761,2.141887659699094,0.5020263274235438,-0.38655086787023707,-0.3997615651907241,0.04770930716017372,-0.2558686053497298,2.187453572170523,-0.06452581499784397,2.132739507118012,-0.07711309132908688,-0.4129986202657584,0.20659078834565117,0.158101752015416,0.1459248602176856,-0.4129986202657584,-0.29480442366640136,0.6053183644197377,-0.30783379939432337,-0.12770013664497198,-0.42626214908149684,-1.0965344452405135,1.54122881436266,-0.07711309132908688,-0.014411717321070097,-0.8229719076907467
| 3,120
|
Golgi membrane
| 72
| 133
| 3.028966
| 0.002454
|
Q92896,Q7LGA3,P0CG08,Q8N4V1,Q8NBN3,Q9H9S5,Q15363,Q9H7Z7,P61026,Q9UM00,P61019,Q9NTJ5,Q9P2W9,P35613,Q8TBA6,Q16706,Q15392,Q9Y3E0,Q13190,Q96L58,O15260,Q12770,Q8NF37,Q14108,Q10472,Q9BUR5,Q969X5,P98194,O43752,Q10713,Q12907,Q5BJH7,Q8NCH0,P49257,O95197,Q96JB2,P24390,Q11206,P04439,P10321,P83436,Q10471,Q9H0U4,O60476,Q8TB61,Q86Y82,Q8N6T3,P11717,L0R6Q1,O95721,O60499,O95249,O15258,Q9Y282,P49755,Q9H4A6,P51572,O95070,Q8IZA0,P35670,O43505,Q6ZRP7,Q9BVK6,Q8IV08,Q16799,Q9Y371,Q14789,P51790,Q99640,O75396,Q9Y3B3,P52292
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
385,27,639,30,31,657,136,262,516,396,648,399,40,145,272,667,402,416,540,284,285,286,162,22,163,165,681,289,434,54,688,183,57,697,60,188,62,191,704,320,706,707,321,452,200,719,592,587,330,204,81,82,583,84,213,214,339,215,605,342,96,480,624,106,489,364,633,369,512,627,379,381
|
330,1220,3017,2039,1050,583,285,1623,96,1448,2566,434,452,81,1769,627,215,60,82,964,204,731,704,1864,639,320,1067,587,1300,2608,62,3097,2159,145,342,3070,1966,1998,919,1806,697,213,1302,339,369,381,715,2798,2995,1197,3020,2026,648,516,823,1573,986,802,911,706,289,1280,1454,707,163,1873,54,191,286,688,540,1073,22,633,2447,2211,136,402,1431,667,489,183,480,27,2864,719,939,106,605,30,592,31,57,162,200,272,1579,2298,385,681,3083,188,284,916,512,1120,165,624,2585,848,321,1154,214,262,1852,1062,657,399,2089,1290,40,2642,2548,1519,1710,396,84,1139,2731,364,379,416,2532
|
1.1944311691364766,0.010505671581950045,-1.3514648583892033,-0.42626214908149684,0.1459248602176856,0.6620352061775991,1.3597758294429656,-0.21715898005436454,2.4022241001142395,-0.12770013664497198,-0.7389091550000886,0.927934341607611,0.9061643301278702,2.602199126779496,-0.29480442366640136,0.6053183644197377,1.6105455839468559,2.879803953814494,2.5850281645230595,0.23070539012934577,1.6498506656784873,0.4788585457441188,0.5135807473198399,-0.3339693636833012,0.593918331939264,1.2257336786097104,0.13372594148942707,0.6620352061775991,-0.039421957943272905,-0.7668105367504043,2.879803953814494,-1.927226968449506,-0.4795833493036897,2.031328055456678,1.1734842794897706,-1.6009768220571814,-0.38655086787023707,-0.3997615651907241,0.2786781386912482,-0.30783379939432337,0.5251156174631679,1.6302255513335107,-0.039421957943272905,1.1839656140069246,1.0890591952246833,1.0677913957002723,0.5020263274235438,-0.9224287018087298,-1.2603375383129658,0.03533096386757563,-1.3514648583892033,-0.4129986202657584,0.582499249500083,0.7962704004189698,0.3736162256132579,-0.19147680577398604,0.20659078834565117,0.3971446149576911,0.29061838215713776,0.5135807473198399,1.3393208461533432,-0.026905183599894182,-0.12770013664497198,0.5135807473198399,1.9095856653720285,-0.3339693636833012,2.9944511899123603,1.7471650667426148,1.3597758294429656,0.5366310104853638,0.7518164632462099,0.13372594148942707,3.1073290564690894,0.6053183644197377,-0.642176835766896,-0.5064058663136635,2.123579621130263,1.0035932957279798,-0.11501748631498755,0.5710610469198908,0.8404387020294766,1.7664679945101098,0.8514366183973154,3.1073290564690894,-0.9944080393492227,0.5020263274235438,0.2667168001795272,2.34913092241935,0.6394048579900791,3.1073290564690894,0.6620352061775991,3.1073290564690894,2.945536868285547,1.9190248758612094,1.6791862202916965,1.4106528917947436,-0.19147680577398604,-0.5468447617435744,1.0571329664420128,0.5596036536159662,-1.7294767969392169,1.7568231217436605,1.369980905900342,0.29061838215713776,0.8073390961220606,0.09699614240690609,1.9095856653720285,0.6166994167264761,-0.7389091550000886,0.35000601574553336,1.2257336786097104,0.07239784971023856,1.620392445349469,1.4410024664236403,-0.3208887425169809,0.1459248602176856,0.582499249500083,1.0143344206282272,-0.43955226841481043,-0.026905183599894182,3.1073290564690894,-0.7808058429070066,-0.7111258245859526,-0.15313781603736049,-0.2558686053497298,1.0250588936033453,2.559195032678293,0.08470823190970675,-0.8512341644014038,1.11026194950554,1.0784334535521216,0.9820608618699915,-0.6972780863213089
| 3,120
|
Endoplasmic reticulum protein containing complex
| 30
| 58
| 3.028565
| 0.002457
|
Q9Y679,P07237,Q8N4V1,Q15006,P46977,P51571,Q9UBV2,Q9NPA0,Q92643,Q15041,O15269,Q96CS3,Q969N2,Q5J8M3,P13674,Q96S52,Q9H0U3,P04439,Q9Y5M8,Q6NUQ1,Q8N766,Q9UGP8,O94888,P14625,O43681,P04843,Q15005,Q9BUN8,Q8TCT9,Q53GQ0
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
658,768,30,518,270,271,41,277,403,279,280,548,817,689,435,564,576,704,79,718,860,477,738,851,486,487,238,372,251,255
|
1447,280,1767,1469,2662,486,738,704,487,1425,768,435,1399,851,2183,2497,2118,871,270,1572,271,2327,2539,1172,2694,1839,1324,1163,1875,238,518,279,1782,255,689,718,913,30,860,1879,1181,251,403,1390,817,548,564,372,576,277,1205,1395,41,477,2015,1940,79,658
|
-0.12770013664497198,1.3801711028302934,-0.29480442366640136,-0.1404068795755925,-0.8088863866647676,0.8404387020294766,0.4672450365868581,0.5135807473198399,0.8404387020294766,-0.11501748631498755,0.4322851425823638,0.927934341607611,-0.10235882830439685,0.33817003194732587,-0.4929810145479234,-0.6834594520783637,-0.46621274973913956,0.32631335668396794,1.4106528917947436,-0.19147680577398604,1.4106528917947436,-0.5739422113824679,-0.7111258245859526,0.04770930716017372,-0.8229719076907467,-0.3208887425169809,-0.05196213624197448,0.060064905188923254,-0.3339693636833012,1.54122881436266,0.7962704004189698,1.3903464678842952,-0.29480442366640136,1.4812650661362408,0.5366310104853638,0.5020263274235438,0.29061838215713776,3.1073290564690894,0.33817003194732587,-0.3339693636833012,0.04770930716017372,1.5013099754199473,1.0035932957279798,-0.08972406297560863,0.3853906088485544,0.7406578703701303,0.7070727943770848,1.0890591952246833,0.6845910055704713,1.4005070484783886,0.03533096386757563,-0.08972406297560863,3.1073290564690894,0.8624169951839001,-0.3997615651907241,-0.36020808645859054,2.6449491417397626,0.582499249500083
| 3,120
|
Tetrapyrrole metabolic process
| 7
| 19
| 3.028164
| 0.00246
|
P22830,O75027,P30519,P09601,P30536,Q7KZN9,O00264
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
69,131,13,113,338,151,124
|
124,131,2516,1863,113,69,1194,13,338,973,1601,1656,1662,151,788,1312,462,1990,1491
|
2.205598948019345,2.141887659699094,-0.6972780863213089,-0.3339693636833012,2.286688869567451,2.7800795662254263,0.03533096386757563,3.1073290564690894,1.1839656140069246,0.21865884469902433,-0.20430553885186603,-0.23003723432961226,-0.23003723432961226,2.003418073325324,0.42059180507154753,-0.039421957943272905,0.8952535006860544,-0.38655086787023707,-0.1404068795755925
| 3,120
|
Mitochondrial calcium ion transport
| 14
| 17
| 3.019495
| 0.002532
|
Q9BPX6,Q9Y4W6,P35232,Q8IYU8,P45880,Q9H300,Q9UJZ1,Q99623,Q9Y277,Q10713,Q96TA2,P21796,O95202,Q8NE86
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
351,594,553,641,15,269,766,146,44,54,670,11,282,481
|
2113,282,11,553,15,54,641,481,764,1349,670,146,351,269,766,44,594
|
-0.46621274973913956,1.369980905900342,3.1073290564690894,0.7294811048241373,3.1073290564690894,2.9944511899123603,0.593918331939264,0.8514366183973154,0.44395840998636554,-0.06452581499784397,0.5710610469198908,2.031328055456678,1.1524740622552163,1.4207840447832099,0.44395840998636554,3.1073290564690894,0.6620352061775991
| 3,120
|
Atpase coupled transmembrane transporter activity
| 11
| 20
| 3.014985
| 0.00257
|
P08183,P16615,P98194,Q15388,O75027,P20020,P05023,Q04656,P23634,Q9HD20,P35670
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
190,160,289,352,131,388,201,398,430,149,342
|
131,201,661,458,190,160,388,1427,2981,430,1069,342,741,2047,1871,289,398,352,149,1618
|
2.141887659699094,1.6596427578574324,0.5710610469198908,0.8952535006860544,1.7471650667426148,1.9472674467092672,1.04645811026075,-0.11501748631498755,-1.2302452877439438,0.9387936429122186,0.13372594148942707,1.1734842794897706,0.4672450365868581,-0.42626214908149684,-0.3339693636833012,1.3393208461533432,1.0143344206282272,1.1419450738425903,2.022036880868175,-0.20430553885186603
| 3,120
|
oxidase
| 8
| 15
| 3.005559
| 0.002651
|
P13073,P20674,Q6ZRP7,P14406,Q15800,O75880,O43819,O75845
|
Functions
|
Panther Protein class
|
panther_protein_class
|
9,66,480,10,239,273,217,347
|
995,217,1625,347,273,1256,9,10,1145,66,973,1601,239,480,573
|
0.19450113637357203,1.6006849247164414,-0.21715898005436454,1.1524740622552163,1.4005070484783886,-0.014411717321070097,3.1073290564690894,3.1073290564690894,0.07239784971023856,2.7884423176310245,0.21865884469902433,-0.20430553885186603,1.54122881436266,0.8514366183973154,0.6845910055704713
| 3,120
|
Glycerophospholipid biosynthesis
| 11
| 31
| 3.003807
| 0.002666
|
Q96N66,Q8NF37,P35790,Q9UG56,Q8IV08,Q53H12,Q9NQZ5,Q9NPH0,Q9BVG9,Q8NCC3,Q8N2A8
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
290,162,194,267,106,171,234,37,176,120,413
|
1083,1941,728,444,2780,2589,194,1319,714,1275,1806,2328,1971,171,987,794,106,413,1017,120,162,804,290,2250,1247,176,1561,37,234,582,267
|
0.12150490797103468,-0.37336641310163715,0.49045228472298324,0.9170579238372758,-0.9081276149528227,-0.7528450205022053,1.6986756619645358,-0.05196213624197448,0.5020263274235438,-0.026905183599894182,-0.30783379939432337,-0.5739422113824679,-0.38655086787023707,1.8811924590596094,0.20659078834565117,0.40887832137263497,2.34913092241935,0.9820608618699915,0.1823898035706314,2.2327310420192736,1.9190248758612094,0.3971446149576911,1.3393208461533432,-0.5198580262786188,-0.0019414638218673386,1.8526851103515125,-0.1786726765570447,3.1073290564690894,1.5611034542199569,0.6733223906940821,1.4309005541628823
| 3,120
|
Mitochondrial myopathy
| 9
| 30
| 2.999614
| 0.002703
|
Q86Y39,Q53H12,O60313,Q96CU9,Q9Y6M9,O96000,P00846,P00403,Q8IUX1
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
170,171,203,48,80,180,61,94,223
|
3107,203,1770,577,1423,1127,180,94,61,1023,579,2199,2071,2984,781,1090,171,170,223,48,1392,1370,1332,2216,245,470,1186,1595,2389,80
|
-2.3244806247371206,1.6498506656784873,-0.29480442366640136,0.6733223906940821,-0.11501748631498755,0.08470823190970675,1.795323913719972,2.4198350975517866,2.879803953814494,0.17025670420391295,0.6733223906940821,-0.5064058663136635,-0.43955226841481043,-1.2302452877439438,0.42059180507154753,0.12150490797103468,1.8811924590596094,1.8906694939515276,1.5809220421218821,3.067214874831629,-0.08972406297560863,-0.07711309132908688,-0.05196213624197448,-0.5064058663136635,1.5212977725567718,0.8733798938179188,0.04770930716017372,-0.19147680577398604,-0.6011513795208029,2.6449491417397626
| 3,120
|
Phospholipid metabolism
| 25
| 47
| 2.994159
| 0.002752
|
Q9UG56,Q9NPH0,Q9NTJ5,Q8N2A8,Q86UL3,Q8WWI5,Q96N66,Q8NF37,Q8IY17,Q53H12,Q9BVG9,P61106,Q10713,Q9NUQ2,O95674,P35790,O00459,Q9NZC3,P43304,O75131,Q8TBX8,Q8IV08,Q96PE3,Q9NQZ5,Q8NCC3
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
267,37,399,413,794,804,290,162,814,171,176,823,54,582,444,194,456,207,714,728,735,106,623,234,120
|
2808,456,1083,1941,728,444,2780,2589,821,1010,194,1319,1402,714,1275,1806,2328,823,1971,1130,54,171,987,794,106,814,413,1017,1058,120,162,735,804,290,623,2491,2250,1247,864,176,1561,37,234,399,582,207,267
|
-0.9367611784117341,0.8952535006860544,0.12150490797103468,-0.37336641310163715,0.49045228472298324,0.9170579238372758,-0.9081276149528227,-0.7528450205022053,0.3736162256132579,0.1823898035706314,1.6986756619645358,-0.05196213624197448,-0.10235882830439685,0.5020263274235438,-0.026905183599894182,-0.30783379939432337,-0.5739422113824679,0.3736162256132579,-0.38655086787023707,0.08470823190970675,2.9944511899123603,1.8811924590596094,0.20659078834565117,0.40887832137263497,2.34913092241935,0.3853906088485544,0.9820608618699915,0.1823898035706314,0.1459248602176856,2.2327310420192736,1.9190248758612094,0.4788585457441188,0.3971446149576911,1.3393208461533432,0.6166994167264761,-0.6696697876094331,-0.5198580262786188,-0.0019414638218673386,0.33817003194732587,1.8526851103515125,-0.1786726765570447,3.1073290564690894,1.5611034542199569,1.0143344206282272,0.6733223906940821,1.6498506656784873,1.4309005541628823
| 3,120
|
Oxidoreduction driven active transmembrane transporter activity
| 9
| 32
| 2.988509
| 0.002803
|
P13073,P20674,O95169,Q9P0J0,Q9Y6M9,Q9UDW1,O96000,Q7KZN9,P00403
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
9,66,292,143,80,42,180,151,94
|
3107,744,995,2718,1569,1770,577,1423,1127,376,292,1192,2017,180,94,1023,965,1256,9,2199,66,2071,1359,1320,2984,1655,1075,1407,151,143,42,80
|
-2.3244806247371206,0.45561168292170245,0.19450113637357203,-0.8512341644014038,-0.19147680577398604,-0.29480442366640136,0.6733223906940821,-0.11501748631498755,0.08470823190970675,1.0784334535521216,1.3290708428266285,0.03533096386757563,-0.4129986202657584,1.795323913719972,2.4198350975517866,0.17025670420391295,0.23070539012934577,-0.014411717321070097,3.1073290564690894,-0.5064058663136635,2.7884423176310245,-0.43955226841481043,-0.07711309132908688,-0.05196213624197448,-1.2302452877439438,-0.23003723432961226,0.13372594148942707,-0.10235882830439685,2.003418073325324,2.068372036315107,3.1073290564690894,2.6449491417397626
| 3,120
|
Cytochrome complex assembly
| 8
| 12
| 2.984507
| 0.00284
|
Q15070,Q9Y276,O75880,Q69YU5,Q9Y2R0,Q7KZN9,O43819,Q6DKK2
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
77,241,273,25,45,151,217,383
|
217,273,1320,1171,77,25,383,151,504,947,241,45
|
1.6006849247164414,1.4005070484783886,-0.05196213624197448,0.04770930716017372,2.695918388459061,3.1073290564690894,1.0677913957002723,2.003418073325324,0.8183900031612562,0.2547342844462805,1.54122881436266,3.1073290564690894
| 3,120
|
Abnormal circulating lipid concentration
| 34
| 74
| 2.983572
| 0.002849
|
O75381,Q15738,Q03252,Q15392,O75880,P23786,P50402,P31751,P50416,P06280,Q96MF7,O43772,P40855,P02545,Q9UJS0,P49257,Q15904,Q10471,P22830,Q9NZJ7,Q9BV10,Q9BTV4,P37268,O75844,O75845,Q9Y4P3,P09622,Q9NVI7,P38571,O75431,O95470,Q16836,Q15800,O75648
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
387,651,526,402,273,155,156,663,161,159,288,291,436,560,311,697,192,707,69,216,346,475,218,90,347,484,354,231,229,357,105,618,239,615
|
2222,1295,2692,291,1624,387,357,615,90,347,273,105,560,159,2258,354,2834,69,155,839,1400,663,2158,2745,2891,218,229,436,1319,2646,2161,697,932,156,161,2519,943,2925,2328,934,842,2050,1130,526,1538,707,901,2075,708,1057,402,651,239,192,618,1329,2581,2545,1348,861,817,288,475,346,1043,1062,231,216,1588,2820,311,1138,484,2703
|
-0.5198580262786188,-0.039421957943272905,-0.8229719076907467,1.3290708428266285,-0.21715898005436454,1.04645811026075,1.120839071139155,0.6166994167264761,2.4374031190390943,1.1524740622552163,1.4005070484783886,2.34913092241935,0.7070727943770848,1.9472674467092672,-0.533337616964219,1.1314000946481249,-0.9655209099750421,2.7800795662254263,1.9940903702899961,0.35000601574553336,-0.10235882830439685,0.5710610469198908,-0.4795833493036897,-0.8796190081405505,-1.0379803402121284,1.6006849247164414,1.5710197329219444,0.927934341607611,-0.05196213624197448,-0.7948310791463405,-0.4795833493036897,0.5251156174631679,0.2667168001795272,1.9940903702899961,1.9472674467092672,-0.6972780863213089,0.2547342844462805,-1.081846393052922,-0.5739422113824679,0.2667168001795272,0.35000601574553336,-0.42626214908149684,0.08470823190970675,0.7851838529268446,-0.16589304761576545,0.5135807473198399,0.30253761226112147,-0.43955226841481043,0.5135807473198399,0.1459248602176856,1.0035932957279798,0.582499249500083,1.54122881436266,1.7471650667426148,0.6166994167264761,-0.05196213624197448,-0.7389091550000886,-0.7111258245859526,-0.06452581499784397,0.33817003194732587,0.3853906088485544,1.3495558255696736,0.8624169951839001,1.1629871131431153,0.158101752015416,0.1459248602176856,1.5710197329219444,1.6105455839468559,-0.19147680577398604,-0.9367611784117341,1.2672525814950062,0.08470823190970675,0.8514366183973154,-0.8229719076907467
| 3,120
|
Secondary active transmembrane transporter activity
| 14
| 20
| 2.982969
| 0.002855
|
P12236,P41440,Q9H936,P12235,P08195,Q15043,Q15758,Q02978,Q9Y6M7,Q9UBX3,P51790,P05141,O95202,Q8NE86
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
609,508,777,579,675,334,753,784,506,83,369,729,282,481
|
282,729,675,579,609,508,369,920,1106,783,1072,784,334,753,481,1081,1787,777,83,506
|
1.369980905900342,0.49045228472298324,0.5596036536159662,0.6733223906940821,0.628061558250135,0.8073390961220606,1.0890591952246833,0.2786781386912482,0.10926167126011344,0.42059180507154753,0.13372594148942707,0.42059180507154753,1.1944311691364766,0.45561168292170245,0.8514366183973154,0.13372594148942707,-0.29480442366640136,0.4322851425823638,2.559195032678293,0.8183900031612562
| 3,120
|
Organelle fusion
| 30
| 52
| 2.97715
| 0.002909
|
Q8TB36,Q9BZG1,O15400,P06493,Q9H300,Q8N2A8,Q13190,P31751,Q9BSR8,Q9H6R6,Q9Y3E7,O43752,Q12846,Q9NX63,Q9UQN3,Q9Y4W6,Q86Y82,Q9GZY8,O60313,O95721,O60499,O95249,Q12981,Q96E52,Q9Y6C9,P02786,Q9P253,O95140,Q9UJZ1,O75396
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
642,392,134,767,269,413,540,663,422,297,559,434,567,443,451,594,719,336,203,204,81,82,221,225,227,630,375,495,766,627
|
2689,2039,134,434,203,2390,81,1769,627,495,82,964,204,630,1268,767,1862,1864,663,954,2989,854,2026,567,221,540,936,2864,719,2169,413,642,225,892,422,392,336,2086,269,297,1217,895,443,375,1855,766,1963,807,451,559,594,227
|
-0.8229719076907467,-0.42626214908149684,2.132739507118012,0.927934341607611,1.6498506656784873,-0.6147981757408897,2.602199126779496,-0.29480442366640136,0.6053183644197377,0.8294231843173793,2.5850281645230595,0.23070539012934577,1.6498506656784873,0.6053183644197377,-0.026905183599894182,0.4322851425823638,-0.3339693636833012,-0.3339693636833012,0.5710610469198908,0.24273050882000022,-1.2452739049804467,0.33817003194732587,-0.4129986202657584,0.6958411178937519,1.5908104250465758,0.7518164632462099,0.2667168001795272,-0.9944080393492227,0.5020263274235438,-0.4795833493036897,0.9820608618699915,0.593918331939264,1.5809220421218821,0.314435910199321,0.9604611324316131,1.04645811026075,1.1944311691364766,-0.43955226841481043,1.4207840447832099,1.318805766980325,0.022929782979047558,0.314435910199321,0.927934341607611,1.0890591952246833,-0.3208887425169809,0.44395840998636554,-0.37336641310163715,0.3971446149576911,0.9170579238372758,0.7182861013625904,0.6620352061775991,1.5809220421218821
| 3,120
|
Steroid metabolic process
| 20
| 63
| 2.973789
| 0.002941
|
O15118,P04062,Q15392,Q12770,Q13510,P04035,Q14534,P16435,P05023,O94905,P30536,P37268,O75845,Q8WTV0,P38571,O95470,Q16850,Q15800,P38435,Q53GQ0
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
141,275,402,286,21,419,167,298,201,331,338,218,347,101,229,105,109,239,250,255
|
141,424,347,331,105,696,419,275,201,2993,1676,645,2781,298,2608,870,2392,2416,1069,338,888,218,250,229,2349,747,932,1970,943,2708,1196,1536,842,2001,2649,1507,286,21,3089,167,708,2943,2448,402,1281,2619,651,239,109,255,957,1412,101,2384,992,2385,1122,1154,1588,1937,1648,2362,1735
|
2.068372036315107,0.9496358869067834,1.1524740622552163,1.1944311691364766,2.34913092241935,0.5251156174631679,0.9604611324316131,1.4005070484783886,1.6596427578574324,-1.2603375383129658,-0.2429404073162766,0.582499249500083,-0.9081276149528227,1.3085255697617286,-0.7668105367504043,0.32631335668396794,-0.6147981757408897,-0.6284732846345887,0.13372594148942707,1.1839656140069246,0.314435910199321,1.6006849247164414,1.5013099754199473,1.5710197329219444,-0.5875327673192509,0.45561168292170245,0.2667168001795272,-0.38655086787023707,0.2547342844462805,-0.837087785495116,0.03533096386757563,-0.16589304761576545,0.35000601574553336,-0.3997615651907241,-0.7948310791463405,-0.15313781603736049,1.3597758294429656,3.1073290564690894,-1.8111255729851865,1.9001338837009643,0.5135807473198399,-1.1260105908189355,-0.642176835766896,1.0035932957279798,-0.026905183599894182,-0.7668105367504043,0.582499249500083,1.54122881436266,2.3045849534352927,1.4812650661362408,0.24273050882000022,-0.10235882830439685,2.3757265160314076,-0.6011513795208029,0.20659078834565117,-0.6011513795208029,0.09699614240690609,0.07239784971023856,-0.19147680577398604,-0.36020808645859054,-0.21715898005436454,-0.5875327673192509,-0.2688219354682781
| 3,120
|
Vacuole organization
| 22
| 55
| 2.967742
| 0.003
|
O14773,Q9BZG1,Q96GC9,P04062,P11117,P16615,Q14108,Q9UHD9,P50897,Q9Y3E7,Q13099,Q9UQN3,O75503,Q9H0U4,P07686,Q9Y371,P10253,Q9P253,O95140,O75787,P54802,O75396
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
0,392,265,275,8,160,22,294,16,559,568,451,64,321,608,364,365,375,495,501,119,627
|
2512,0,2324,627,64,501,495,964,275,1862,608,365,8,160,1010,1998,1838,16,954,119,1197,823,802,568,22,1810,956,667,957,719,922,735,1579,2104,265,1644,2215,392,321,2086,1285,1438,2387,895,375,294,1592,1963,980,451,2643,364,559,1828,3091
|
-0.6972780863213089,3.1073290564690894,-0.5739422113824679,0.6053183644197377,2.8632777541578998,0.8183900031612562,0.8294231843173793,0.23070539012934577,1.4005070484783886,-0.3339693636833012,0.628061558250135,1.0996686756577085,3.1073290564690894,1.9472674467092672,0.1823898035706314,-0.3997615651907241,-0.3208887425169809,3.1073290564690894,0.24273050882000022,2.2327310420192736,0.03533096386757563,0.3736162256132579,0.3971446149576911,0.6958411178937519,3.1073290564690894,-0.30783379939432337,0.24273050882000022,0.5710610469198908,0.24273050882000022,0.5020263274235438,0.2786781386912482,0.4788585457441188,-0.19147680577398604,-0.4528690958405845,1.4309005541628823,-0.21715898005436454,-0.5064058663136635,1.04645811026075,1.2257336786097104,-0.43955226841481043,-0.026905183599894182,-0.11501748631498755,-0.6011513795208029,0.314435910199321,1.0890591952246833,1.3290708428266285,-0.19147680577398604,-0.37336641310163715,0.21865884469902433,0.9170579238372758,-0.7808058429070066,1.11026194950554,0.7182861013625904,-0.30783379939432337,-1.8440810849163076
| 3,120
|
Oxidase
| 9
| 21
| 2.966464
| 0.003012
|
P20674,P14406,Q15800,O75880,O43819,O43169,O15260,Q15067,O75845
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
66,10,239,273,217,2,285,382,347
|
995,868,285,2,217,347,273,1256,2834,2391,10,1145,66,2282,973,932,382,239,480,2080,1043
|
0.19450113637357203,0.32631335668396794,1.3597758294429656,3.1073290564690894,1.6006849247164414,1.1524740622552163,1.4005070484783886,-0.014411717321070097,-0.9655209099750421,-0.6147981757408897,3.1073290564690894,0.07239784971023856,2.7884423176310245,-0.5468447617435744,0.21865884469902433,0.2667168001795272,1.0677913957002723,1.54122881436266,0.8514366183973154,-0.43955226841481043,0.158101752015416
| 3,120
|
Sterol binding
| 8
| 17
| 2.965267
| 0.003024
|
Q14108,P45880,O15118,O94905,P30536,P21796,Q12770,O95772
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
22,15,141,331,338,11,286,7
|
141,424,331,7,2152,11,2608,870,338,888,15,842,286,22,992,736,1561
|
2.068372036315107,0.9496358869067834,1.1944311691364766,3.1073290564690894,-0.4795833493036897,3.1073290564690894,-0.7668105367504043,0.32631335668396794,1.1839656140069246,0.314435910199321,3.1073290564690894,0.35000601574553336,1.3597758294429656,3.1073290564690894,0.20659078834565117,0.4788585457441188,-0.1786726765570447
| 3,120
|
Mitochondrial complex iv assembly
| 9
| 13
| 2.963684
| 0.00304
|
P13073,P20674,P14406,Q9Y6N1,Q9Y2R0,Q96I36,O43819,Q7KZN9,P00403
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
9,66,10,404,45,504,217,151,94
|
744,217,94,561,1256,9,10,1145,66,151,504,45,404
|
0.45561168292170245,1.6006849247164414,2.4198350975517866,0.7070727943770848,-0.014411717321070097,3.1073290564690894,3.1073290564690894,0.07239784971023856,2.7884423176310245,2.003418073325324,0.8183900031612562,3.1073290564690894,1.0035932957279798
| 3,120
|
Organelle membrane contact site
| 10
| 14
| 2.961179
| 0.003065
|
Q15388,Q96N66,P27824,Q5XKP0,Q9NTJ5,P51572,Q96TC7,O96008,Q9Y320,O95772
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
352,290,324,132,399,339,340,502,515,7
|
791,1190,1570,7,502,324,339,352,132,574,290,340,399,515
|
0.40887832137263497,0.03533096386757563,-0.19147680577398604,3.1073290564690894,0.8183900031612562,1.215315149662245,1.1839656140069246,1.1419450738425903,2.141887659699094,0.6845910055704713,1.3393208461533432,1.1839656140069246,1.0143344206282272,0.8073390961220606
| 3,120
|
Respiratory electron transport chain
| 17
| 53
| 2.960627
| 0.00307
|
P13073,P20674,P09622,O95169,P14927,O95168,Q9H3K2,Q9Y6M9,P04062,Q9UDW1,P21912,O96000,Q9UJS0,O14949,Q7KZN9,O43819,P00403
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
9,66,354,292,293,376,367,80,275,42,178,180,311,1,151,217,94
|
3107,744,995,1,2718,217,1569,1770,577,1423,1127,425,376,292,1192,2017,180,94,1023,275,1887,767,965,354,1256,9,2391,1888,293,1145,2199,66,178,2071,2157,2236,714,1320,2984,1655,1606,519,1075,1407,151,3045,2998,2216,367,777,42,311,80
|
-2.3244806247371206,0.45561168292170245,0.19450113637357203,3.1073290564690894,-0.8512341644014038,1.6006849247164414,-0.19147680577398604,-0.29480442366640136,0.6733223906940821,-0.11501748631498755,0.08470823190970675,0.9496358869067834,1.0784334535521216,1.3290708428266285,0.03533096386757563,-0.4129986202657584,1.795323913719972,2.4198350975517866,0.17025670420391295,1.4005070484783886,-0.34707577428405895,0.4322851425823638,0.23070539012934577,1.1314000946481249,-0.014411717321070097,3.1073290564690894,-0.6147981757408897,-0.34707577428405895,1.3290708428266285,0.07239784971023856,-0.5064058663136635,2.7884423176310245,1.8049164509564872,-0.43955226841481043,-0.4795833493036897,-0.5198580262786188,0.5020263274235438,-0.05196213624197448,-1.2302452877439438,-0.23003723432961226,-0.20430553885186603,0.7962704004189698,0.13372594148942707,-0.10235882830439685,2.003418073325324,-1.4594351482439722,-1.2754363677556144,-0.5064058663136635,1.0996686756577085,0.4322851425823638,3.1073290564690894,1.2672525814950062,2.6449491417397626
| 3,120
|
Abnormal retinal artery morphology
| 7
| 20
| 2.956331
| 0.003113
|
P17900,Q13510,P16278,Q9NZJ7,P21964,P10619,P00846
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
68,21,117,216,92,91,61
|
885,2692,61,1023,252,608,91,2181,117,68,92,2158,2635,2050,21,1057,1390,216,2820,484
|
0.314435910199321,-0.8229719076907467,2.879803953814494,0.17025670420391295,1.4912946822328113,0.628061558250135,2.4374031190390943,-0.4929810145479234,2.241752275250984,2.7800795662254263,2.4374031190390943,-0.4795833493036897,-0.7808058429070066,-0.42626214908149684,3.1073290564690894,0.1459248602176856,-0.08972406297560863,1.6105455839468559,-0.9367611784117341,0.8514366183973154
| 3,120
|
Porphyrin containing compound metabolic process
| 7
| 17
| 2.955811
| 0.003118
|
P22830,O75027,P30519,P09601,P30536,Q7KZN9,O00264
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
69,131,13,113,338,151,124
|
124,131,2516,1863,113,69,1194,13,338,973,1601,1656,1662,151,462,1990,1491
|
2.205598948019345,2.141887659699094,-0.6972780863213089,-0.3339693636833012,2.286688869567451,2.7800795662254263,0.03533096386757563,3.1073290564690894,1.1839656140069246,0.21865884469902433,-0.20430553885186603,-0.23003723432961226,-0.23003723432961226,2.003418073325324,0.8952535006860544,-0.38655086787023707,-0.1404068795755925
| 3,120
|
Glycerophospholipid biosynthetic process
| 22
| 38
| 2.948651
| 0.003192
|
Q9UG56,Q9NPH0,Q9NTJ5,Q92643,Q86UL3,Q8WWI5,Q96N66,Q8NF37,Q969N2,Q8WVX9,Q9BVG9,Q96S52,Q10713,Q9NX62,Q9NUQ2,O95674,P35790,O00459,Q6IAN0,Q8TBX8,Q5H8A4,Q96PE3
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
267,37,399,403,794,804,290,162,817,816,176,564,54,55,582,444,194,456,844,735,233,623
|
2808,456,1083,1941,1794,1169,444,2939,2780,2044,194,1402,1275,1130,54,233,844,987,1367,794,162,735,816,804,403,817,290,623,564,1247,864,176,1371,37,399,582,55,267
|
-0.9367611784117341,0.8952535006860544,0.12150490797103468,-0.37336641310163715,-0.30783379939432337,0.04770930716017372,0.9170579238372758,-1.1260105908189355,-0.9081276149528227,-0.42626214908149684,1.6986756619645358,-0.10235882830439685,-0.026905183599894182,0.08470823190970675,2.9944511899123603,1.5611034542199569,0.35000601574553336,0.20659078834565117,-0.07711309132908688,0.40887832137263497,1.9190248758612094,0.4788585457441188,0.3853906088485544,0.3971446149576911,1.0035932957279798,0.3853906088485544,1.3393208461533432,0.6166994167264761,0.7070727943770848,-0.0019414638218673386,0.33817003194732587,1.8526851103515125,-0.07711309132908688,3.1073290564690894,1.0143344206282272,0.6733223906940821,2.986321497503092,1.4309005541628823
| 3,120
|
Passive transmembrane transporter activity
| 17
| 32
| 2.938856
| 0.003294
|
Q9BVC6,Q9NW15,P0CG08,P24539,Q8NE86,Q9UM00,P45880,P06576,Q9Y277,O96008,Q4KMQ2,P51790,P21796,P56385,P00846,O75964,Q8TDW0
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
581,258,639,12,481,396,15,458,44,502,634,369,11,348,61,6,547
|
2301,660,6,502,61,458,1598,1862,2152,639,11,12,1273,801,2047,15,1999,369,1479,348,2694,2801,634,481,547,998,1079,581,258,396,44,3098
|
-0.5603795848494529,0.5710610469198908,3.1073290564690894,0.8183900031612562,2.879803953814494,0.8952535006860544,-0.20430553885186603,-0.3339693636833012,-0.4795833493036897,0.593918331939264,3.1073290564690894,3.1073290564690894,-0.026905183599894182,0.3971446149576911,-0.42626214908149684,3.1073290564690894,-0.3997615651907241,1.0890591952246833,-0.1404068795755925,1.1524740622552163,-0.8229719076907467,-0.9224287018087298,0.6053183644197377,0.8514366183973154,0.7406578703701303,0.19450113637357203,0.13372594148942707,0.6733223906940821,1.4712210819843028,1.0250588936033453,3.1073290564690894,-1.9945391164615682
| 3,120
|
Secretory granule membrane
| 20
| 70
| 2.938639
| 0.003297
|
Q15363,P35613,P11279,Q5T9A4,O15260,Q8NF37,Q07065,P30519,Q92542,P42785,Q8TAD4,Q969Q5,P10321,Q08722,O95721,P49755,Q9NZJ7,Q93050,P13473,O00264
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
136,145,278,283,285,162,20,13,174,46,179,58,320,206,204,213,216,88,228,124
|
2689,124,981,727,285,2149,1100,728,2588,2042,501,2515,204,731,1598,365,320,278,587,228,2923,953,739,1300,13,1801,2024,145,871,46,2238,213,1721,954,854,2798,733,516,823,1553,3114,1745,2289,20,206,1841,2241,1163,812,136,634,2132,283,957,680,162,574,179,174,88,58,2250,848,576,893,216,1290,2362,1493,1007
|
-0.8229719076907467,2.205598948019345,0.20659078834565117,0.49045228472298324,1.3597758294429656,-0.4795833493036897,0.10926167126011344,0.49045228472298324,-0.7528450205022053,-0.42626214908149684,0.8183900031612562,-0.6972780863213089,1.6498506656784873,0.4788585457441188,-0.20430553885186603,1.0996686756577085,1.2257336786097104,1.3903464678842952,0.6620352061775991,1.5710197329219444,-1.081846393052922,0.24273050882000022,0.4672450365868581,-0.039421957943272905,3.1073290564690894,-0.30783379939432337,-0.4129986202657584,2.031328055456678,0.32631335668396794,3.083286891375091,-0.5198580262786188,1.6302255513335107,-0.2688219354682781,0.24273050882000022,0.33817003194732587,-0.9224287018087298,0.4788585457441188,0.7962704004189698,0.3736162256132579,-0.1786726765570447,-5.304515529384527,-0.28180050541945734,-0.5468447617435744,3.1073290564690894,1.6498506656784873,-0.3208887425169809,-0.5198580262786188,0.060064905188923254,0.3853906088485544,2.123579621130263,0.6053183644197377,-0.46621274973913956,1.369980905900342,0.24273050882000022,0.5596036536159662,1.9190248758612094,0.6845910055704713,1.8049164509564872,1.862200304747472,2.5246065738795194,2.92915905420511,-0.5198580262786188,0.35000601574553336,0.6845910055704713,0.314435910199321,1.6105455839468559,-0.026905183599894182,-0.5875327673192509,-0.1404068795755925,0.19450113637357203
| 3,120
|
Import across plasma membrane
| 14
| 21
| 2.926253
| 0.003431
|
P05026,P41440,P08195,P05023,P30825,Q15043,Q15758,P05556,P23634,P54709,Q15041,O75915,P31751,Q8TDW0
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
661,508,675,201,76,334,753,586,430,748,279,628,663,547
|
1398,628,201,661,586,675,1067,430,76,663,918,508,748,783,1116,279,334,753,547,1081,2216
|
-0.10235882830439685,0.6053183644197377,1.6596427578574324,0.5710610469198908,0.6620352061775991,0.5596036536159662,0.13372594148942707,0.9387936429122186,2.704378541877951,0.5710610469198908,0.2786781386912482,0.8073390961220606,0.45561168292170245,0.42059180507154753,0.09699614240690609,1.3903464678842952,1.1944311691364766,0.45561168292170245,0.7406578703701303,0.13372594148942707,-0.5064058663136635
| 3,120
|
ATP synthase
| 8
| 20
| 2.925585
| 0.003438
|
Q9Y487,P24539,P56385,Q93050,Q96IX5,P00846,O75964,Q15904
|
Functions
|
Panther Protein class
|
panther_protein_class
|
130,12,348,88,315,61,6,192
|
660,6,61,458,1427,2981,12,1273,801,2047,1999,1479,348,1871,192,1901,88,315,1618,130
|
0.5710610469198908,3.1073290564690894,2.879803953814494,0.8952535006860544,-0.11501748631498755,-1.2302452877439438,3.1073290564690894,-0.026905183599894182,0.3971446149576911,-0.42626214908149684,-0.3997615651907241,-0.1404068795755925,1.1524740622552163,-0.3339693636833012,1.7471650667426148,-0.34707577428405895,2.5246065738795194,1.236136635275694,-0.20430553885186603,2.1510241118925633
| 3,120
|
Atp synthesis coupled electron transport
| 12
| 40
| 2.925096
| 0.003444
|
P13073,P20674,P09622,O95169,P14927,Q9H3K2,Q9Y6M9,Q9UDW1,O96000,O14949,Q7KZN9,P00403
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
9,66,354,292,293,367,80,42,180,1,151,94
|
3107,744,995,1,2718,1569,1770,577,1423,1127,376,292,1192,2017,180,94,1023,767,965,354,1256,9,1888,293,1145,2199,66,2071,2157,1320,2984,1655,1075,1407,151,3045,2216,367,42,80
|
-2.3244806247371206,0.45561168292170245,0.19450113637357203,3.1073290564690894,-0.8512341644014038,-0.19147680577398604,-0.29480442366640136,0.6733223906940821,-0.11501748631498755,0.08470823190970675,1.0784334535521216,1.3290708428266285,0.03533096386757563,-0.4129986202657584,1.795323913719972,2.4198350975517866,0.17025670420391295,0.4322851425823638,0.23070539012934577,1.1314000946481249,-0.014411717321070097,3.1073290564690894,-0.34707577428405895,1.3290708428266285,0.07239784971023856,-0.5064058663136635,2.7884423176310245,-0.43955226841481043,-0.4795833493036897,-0.05196213624197448,-1.2302452877439438,-0.23003723432961226,0.13372594148942707,-0.10235882830439685,2.003418073325324,-1.4594351482439722,-0.5064058663136635,1.0996686756577085,3.1073290564690894,2.6449491417397626
| 3,120
|
Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen
| 10
| 29
| 2.924687
| 0.003448
|
Q6UW02,Q14534,Q32P28,P30519,P16435,Q16850,Q15800,Q9NVH6,P09601,O75845
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
26,167,232,13,298,109,239,374,113,347
|
2704,1765,981,1625,1141,2042,347,951,768,113,435,298,1428,13,1092,1896,1405,167,239,109,232,2055,26,2503,573,656,2563,374,1649
|
-0.837087785495116,-0.29480442366640136,0.20659078834565117,-0.21715898005436454,0.07239784971023856,-0.42626214908149684,1.1524740622552163,0.24273050882000022,0.4322851425823638,2.286688869567451,0.927934341607611,1.3085255697617286,-0.11501748631498755,3.1073290564690894,0.12150490797103468,-0.34707577428405895,-0.10235882830439685,1.9001338837009643,1.54122881436266,2.3045849534352927,1.5611034542199569,-0.42626214908149684,3.1073290564690894,-0.6834594520783637,0.6845910055704713,0.582499249500083,-0.7250028020839093,1.0890591952246833,-0.21715898005436454
| 3,120
|
Huntingtons disease
| 16
| 79
| 2.924132
| 0.003454
|
P13073,P14406,P20674,P24539,O95169,P45880,P22695,Q9Y6M9,Q9UDW1,P21912,Q9Y277,O96000,O14949,P21796,P00846,P00403
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
9,10,66,12,292,15,205,80,42,178,44,180,1,11,61,94
|
3107,744,995,1,1996,2718,1569,1770,577,1423,1127,660,2515,376,292,1192,2017,2921,180,94,61,1887,1739,729,458,965,1035,1529,561,1256,579,609,9,10,293,1145,2721,1104,2199,66,11,178,205,12,2201,1273,2954,2071,1235,2157,1359,801,2646,15,1320,1999,2984,1655,1056,1700,2882,2240,2826,1363,2812,2291,1898,384,1132,2211,1075,1407,1311,2031,2700,42,1157,44,80
|
-2.3244806247371206,0.45561168292170245,0.19450113637357203,3.1073290564690894,-0.3997615651907241,-0.8512341644014038,-0.19147680577398604,-0.29480442366640136,0.6733223906940821,-0.11501748631498755,0.08470823190970675,0.5710610469198908,-0.6972780863213089,1.0784334535521216,1.3290708428266285,0.03533096386757563,-0.4129986202657584,-1.081846393052922,1.795323913719972,2.4198350975517866,2.879803953814494,-0.34707577428405895,-0.28180050541945734,0.49045228472298324,0.8952535006860544,0.23070539012934577,0.158101752015416,-0.16589304761576545,0.7070727943770848,-0.014411717321070097,0.6733223906940821,0.628061558250135,3.1073290564690894,3.1073290564690894,1.3290708428266285,0.07239784971023856,-0.8512341644014038,0.10926167126011344,-0.5064058663136635,2.7884423176310245,3.1073290564690894,1.8049164509564872,1.6498506656784873,3.1073290564690894,-0.5064058663136635,-0.026905183599894182,-1.1704774288251414,-0.43955226841481043,-0.0019414638218673386,-0.4795833493036897,-0.07711309132908688,0.3971446149576911,-0.7948310791463405,3.1073290564690894,-0.05196213624197448,-0.3997615651907241,-1.2302452877439438,-0.23003723432961226,0.1459248602176856,-0.2558686053497298,-1.02342381486338,-0.5198580262786188,-0.9511251967557256,-0.07711309132908688,-0.9367611784117341,-0.5468447617435744,-0.34707577428405895,1.0571329664420128,0.08470823190970675,-0.5064058663136635,0.13372594148942707,-0.10235882830439685,-0.039421957943272905,-0.4129986202657584,-0.8229719076907467,3.1073290564690894,0.07239784971023856,3.1073290564690894,2.6449491417397626
| 3,120
|
Endoplasmic reticulum membrane organization
| 6
| 9
| 2.921838
| 0.00348
|
Q9NQC3,Q15363,Q8NHH9,Q9P2W9,Q15041,Q12981
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
72,136,172,40,279,221
|
928,310,221,279,136,172,1155,72,40
|
0.2667168001795272,1.2672525814950062,1.5908104250465758,1.3903464678842952,2.123579621130263,1.871702741792419,0.07239784971023856,2.7717071857086912,3.1073290564690894
| 3,120
|
Membrane lipid catabolic process
| 7
| 12
| 2.908718
| 0.003629
|
P06280,P17900,Q13510,O95470,P50897,P04066,P06865
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
159,68,21,105,16,237,252
|
105,275,237,159,252,608,68,16,2028,21,575,2089
|
2.34913092241935,1.4005070484783886,1.54122881436266,1.9472674467092672,1.4912946822328113,0.628061558250135,2.7800795662254263,3.1073290564690894,-0.4129986202657584,3.1073290564690894,0.6845910055704713,-0.43955226841481043
| 3,120
|
Organelle inner membrane
| 113
| 244
| 2.907493
| 0.003643
|
Q99720,Q9H9B4,Q16134,Q9H2D1,Q567V2,O94901,Q03252,Q9H9P8,Q9UDW1,Q9Y2R0,Q69YU5,O14949,P18031,Q14728,O43615,O60830,O75964,Q9NVH1,Q9BQ95,P13073,P14406,Q8NI60,P24539,P35232,P09669,Q96CU9,Q13505,Q10713,O14925,P00846,Q9H061,P20674,P12235,O75306,P22830,Q9Y4W6,Q7Z7H8,Q15070,Q9Y6M9,Q9UBX3,O75844,P00403,Q9UDX5,Q13423,Q6PI78,Q5XKP0,O75027,Q9P0J0,Q99623,Q9H1E5,Q7KZN9,P23786,P50402,Q9BUR5,Q70HW3,Q8NBN7,Q86Y39,Q53H12,P21912,O96000,Q6UXV4,P22695,O60313,Q16891,O43819,Q8IUX1,Q8IXM6,Q96E52,Q9Y6C9,Q9NVI7,Q9Y276,Q9NPL8,Q9UG56,Q9H300,Q02127,O75880,O95202,Q5T9A4,O43772,O95169,P14927,Q9BQT8,Q5SNT2,Q9Y2U8,Q9UJS0,Q96IX5,Q9Y512,O95831,P56385,P82933,Q9BPX6,Q6P4A7,O75431,Q9H3K2,Q9HC21,O95168,Q6DKK2,Q6NUK1,Q9Y6N1,Q3ZCQ8,O75746,Q8NC56,Q9NX63,O95674,P06576,Q9Y5J9,Q9UH99,Q9NX14,Q9BTV4,Q8NE86,P20700,Q9BUB7,O96008
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
35,522,519,36,24,524,526,527,42,45,25,1,537,538,539,4,6,542,550,9,10,546,12,553,561,48,52,54,59,61,65,66,579,577,69,594,75,77,80,83,90,94,97,103,123,132,131,143,146,148,151,155,156,165,168,169,170,171,178,180,195,205,203,210,217,223,224,225,227,231,241,245,267,269,276,273,282,283,291,292,293,296,307,308,311,315,323,332,348,349,351,356,357,367,373,376,383,390,404,407,425,441,443,444,458,468,471,470,475,481,478,493,502
|
3107,744,995,59,1,539,2718,291,217,1569,203,4,131,1770,577,1423,1222,357,2113,1127,1224,779,425,90,273,660,6,1128,524,376,292,1192,282,2017,1143,444,332,180,502,94,61,1023,1255,729,458,2945,965,2304,1500,561,1256,2153,579,609,1865,9,10,293,1145,953,537,2199,66,478,178,2392,205,69,1381,155,12,1273,2071,2157,1359,1802,553,801,973,1475,1319,2237,853,714,1320,1999,1968,932,2984,1601,156,2162,1655,855,920,1171,1361,2328,1479,348,2443,610,1107,1701,1777,2397,2207,1872,2786,2398,349,1072,276,784,526,54,1175,761,1749,103,52,1260,538,708,77,519,1075,1407,210,407,171,24,590,307,2404,283,132,25,383,390,1923,356,123,195,2080,168,151,2905,75,170,223,1030,224,641,2213,720,1726,169,441,967,481,546,764,2383,988,824,48,2526,225,2384,1413,1616,1077,315,686,670,146,35,351,550,296,789,475,1370,493,165,2014,1881,1489,2562,1352,1002,1645,65,148,36,1936,269,367,1043,777,522,2829,527,1286,373,1853,2036,245,625,947,542,231,1333,470,443,1004,1466,1186,143,1044,83,42,97,267,471,311,766,241,1650,45,2688,1375,308,1620,1219,1265,594,323,468,2016,227,80,404
|
-2.3244806247371206,0.45561168292170245,0.19450113637357203,2.912744419090262,3.1073290564690894,0.7518164632462099,-0.8512341644014038,1.3290708428266285,1.6006849247164414,-0.19147680577398604,1.6498506656784873,3.1073290564690894,2.141887659699094,-0.29480442366640136,0.6733223906940821,-0.11501748631498755,0.010505671581950045,1.120839071139155,-0.46621274973913956,0.08470823190970675,0.010505671581950045,0.42059180507154753,0.9496358869067834,2.4374031190390943,1.4005070484783886,0.5710610469198908,3.1073290564690894,0.08470823190970675,0.7851838529268446,1.0784334535521216,1.3290708428266285,0.03533096386757563,1.369980905900342,-0.4129986202657584,0.07239784971023856,0.9170579238372758,1.1944311691364766,1.795323913719972,0.8183900031612562,2.4198350975517866,2.879803953814494,0.17025670420391295,-0.014411717321070097,0.49045228472298324,0.8952535006860544,-1.140799018459453,0.23070539012934577,-0.5603795848494529,-0.15313781603736049,0.7070727943770848,-0.014411717321070097,-0.4795833493036897,0.6733223906940821,0.628061558250135,-0.3339693636833012,3.1073290564690894,3.1073290564690894,1.3290708428266285,0.07239784971023856,0.24273050882000022,0.7629569483379726,-0.5064058663136635,2.7884423176310245,0.8514366183973154,1.8049164509564872,-0.6147981757408897,1.6498506656784873,2.7800795662254263,-0.08972406297560863,1.9940903702899961,3.1073290564690894,-0.026905183599894182,-0.43955226841481043,-0.4795833493036897,-0.07711309132908688,-0.30783379939432337,0.7294811048241373,0.3971446149576911,0.21865884469902433,-0.1404068795755925,-0.05196213624197448,-0.5198580262786188,0.33817003194732587,0.5020263274235438,-0.05196213624197448,-0.3997615651907241,-0.38655086787023707,0.2667168001795272,-1.2302452877439438,-0.20430553885186603,1.9940903702899961,-0.4795833493036897,-0.23003723432961226,0.33817003194732587,0.2786781386912482,0.04770930716017372,-0.07711309132908688,-0.5739422113824679,-0.1404068795755925,1.1524740622552163,-0.642176835766896,0.628061558250135,0.10926167126011344,-0.2558686053497298,-0.29480442366640136,-0.6147981757408897,-0.5064058663136635,-0.3339693636833012,-0.9081276149528227,-0.6147981757408897,1.1524740622552163,0.13372594148942707,1.4005070484783886,0.42059180507154753,0.7851838529268446,2.9944511899123603,0.04770930716017372,0.44395840998636554,-0.28180050541945734,2.358007059486536,3.026879918923703,-0.014411717321070097,0.7629569483379726,0.5135807473198399,2.695918388459061,0.7962704004189698,0.13372594148942707,-0.10235882830439685,1.640044944107091,0.9928354619075869,1.8811924590596094,3.1073290564690894,0.6620352061775991,1.2775937576578875,-0.6147981757408897,1.369980905900342,2.141887659699094,3.1073290564690894,1.0677913957002723,1.04645811026075,-0.36020808645859054,1.1314000946481249,2.2146544100937735,1.6986756619645358,-0.43955226841481043,1.9001338837009643,2.003418073325324,-1.0525695038528717,2.7465320247261675,1.8906694939515276,1.5809220421218821,0.17025670420391295,1.5809220421218821,0.593918331939264,-0.5064058663136635,0.5020263274235438,-0.2688219354682781,1.9001338837009643,0.927934341607611,0.23070539012934577,0.8514366183973154,0.7406578703701303,0.44395840998636554,-0.6011513795208029,0.20659078834565117,0.3736162256132579,3.067214874831629,-0.6972780863213089,1.5809220421218821,-0.6011513795208029,-0.10235882830439685,-0.20430553885186603,0.13372594148942707,1.236136635275694,0.5481269986020768,0.5710610469198908,2.031328055456678,3.1073290564690894,1.1524740622552163,0.7406578703701303,1.318805766980325,0.42059180507154753,0.8624169951839001,-0.07711309132908688,0.8404387020294766,1.9095856653720285,-0.3997615651907241,-0.3339693636833012,-0.1404068795755925,-0.7250028020839093,-0.06452581499784397,0.19450113637357203,-0.21715898005436454,2.8134730400382506,2.022036880868175,3.1073290564690894,-0.36020808645859054,1.4207840447832099,1.0996686756577085,0.158101752015416,0.4322851425823638,0.7962704004189698,-0.9511251967557256,0.7851838529268446,-0.026905183599894182,1.0890591952246833,-0.3208887425169809,-0.4129986202657584,1.5212977725567718,0.6166994167264761,0.2547342844462805,0.7518164632462099,1.5710197329219444,-0.05196213624197448,0.8733798938179188,0.927934341607611,0.19450113637357203,-0.12770013664497198,0.04770930716017372,2.068372036315107,0.158101752015416,2.559195032678293,3.1073290564690894,2.4022241001142395,1.4309005541628823,0.8733798938179188,1.2672525814950062,0.44395840998636554,1.54122881436266,-0.21715898005436454,3.1073290564690894,-0.8088863866647676,-0.07711309132908688,1.2775937576578875,-0.20430553885186603,0.022929782979047558,-0.014411717321070097,0.6620352061775991,1.2257336786097104,0.8843253753961765,-0.3997615651907241,1.5809220421218821,2.6449491417397626,1.0035932957279798
| 3,120
|
Impaired proprioception
| 13
| 38
| 2.90197
| 0.003708
|
O14773,Q13217,Q9NR77,P20700,Q8IV08,O94905,O75298,O95140,P54802,Q9H6K4,O43819,P07196,P00846
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
0,445,322,478,106,331,5,495,119,56,217,186,61
|
1048,0,2222,1793,217,5,331,495,61,1798,186,2153,1271,869,478,2890,2420,508,1090,119,1361,2327,2540,1896,445,717,2381,106,958,2545,816,776,1392,1435,56,322,1735,971
|
0.1459248602176856,3.1073290564690894,-0.5198580262786188,-0.30783379939432337,1.6006849247164414,3.1073290564690894,1.1944311691364766,0.8294231843173793,2.879803953814494,-0.30783379939432337,1.7568231217436605,-0.4795833493036897,-0.026905183599894182,0.32631335668396794,0.8514366183973154,-1.0379803402121284,-0.6284732846345887,0.8073390961220606,0.12150490797103468,2.2327310420192736,-0.07711309132908688,-0.5739422113824679,-0.7111258245859526,-0.34707577428405895,0.9170579238372758,0.5020263274235438,-0.6011513795208029,2.34913092241935,0.24273050882000022,-0.7111258245859526,0.3853906088485544,0.4322851425823638,-0.08972406297560863,-0.11501748631498755,2.9618780425769327,1.2257336786097104,-0.2688219354682781,0.23070539012934577
| 3,120
|
Ion channel transport
| 12
| 28
| 2.89973
| 0.003735
|
P16615,Q9Y487,Q9NW15,P98194,P20020,P05023,Q04656,Q9HD20,P35670,P51790,Q93050,Q15904
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
160,130,258,289,388,201,398,149,342,369,88,192
|
201,661,160,388,1427,2981,430,1801,342,741,2047,369,748,1871,289,398,1405,762,2052,2463,192,634,88,960,149,258,1618,130
|
1.6596427578574324,0.5710610469198908,1.9472674467092672,1.04645811026075,-0.11501748631498755,-1.2302452877439438,0.9387936429122186,-0.30783379939432337,1.1734842794897706,0.4672450365868581,-0.42626214908149684,1.0890591952246833,0.45561168292170245,-0.3339693636833012,1.3393208461533432,1.0143344206282272,-0.10235882830439685,0.44395840998636554,-0.42626214908149684,-0.6559089596214692,1.7471650667426148,0.6053183644197377,2.5246065738795194,0.24273050882000022,2.022036880868175,1.4712210819843028,-0.20430553885186603,2.1510241118925633
| 3,120
|
Proton transporting two sector atpase complex
| 9
| 21
| 2.893124
| 0.003814
|
Q9Y487,P24539,P06576,P56385,Q93050,Q96IX5,P00846,O75964,Q15904
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
130,12,458,348,88,315,61,6,192
|
501,660,6,61,458,1427,2981,12,1273,801,741,2047,1999,1479,348,1871,192,88,315,1618,130
|
0.8183900031612562,0.5710610469198908,3.1073290564690894,2.879803953814494,0.8952535006860544,-0.11501748631498755,-1.2302452877439438,3.1073290564690894,-0.026905183599894182,0.3971446149576911,0.4672450365868581,-0.42626214908149684,-0.3997615651907241,-0.1404068795755925,1.1524740622552163,-0.3339693636833012,1.7471650667426148,2.5246065738795194,1.236136635275694,-0.20430553885186603,2.1510241118925633
| 3,120
|
Optic disc pallor
| 20
| 48
| 2.883186
| 0.003937
|
Q9UG56,Q96L58,Q8WWY3,Q86Y39,Q96CU9,O96000,Q10713,Q9H6K4,P00846,Q9H061,O75306,Q9GZY8,O95831,O60313,Q9Y6M9,Q6P4Q7,Q9NX14,Q8IUX1,O95140,Q9NPL8
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
267,284,541,170,48,180,54,56,61,65,577,336,332,203,80,465,470,223,495,245
|
3107,1567,884,963,2111,1525,1624,203,1770,577,1423,2113,1127,2279,495,332,180,61,704,2181,869,2199,1889,2071,2984,3034,2881,54,465,170,223,2599,922,541,1931,48,284,1370,1332,336,65,56,245,470,1186,267,594,80
|
-2.3244806247371206,-0.19147680577398604,0.314435910199321,0.23070539012934577,-0.46621274973913956,-0.16589304761576545,-0.21715898005436454,1.6498506656784873,-0.29480442366640136,0.6733223906940821,-0.11501748631498755,-0.46621274973913956,0.08470823190970675,-0.5468447617435744,0.8294231843173793,1.1944311691364766,1.795323913719972,2.879803953814494,0.5135807473198399,-0.4929810145479234,0.32631335668396794,-0.5064058663136635,-0.34707577428405895,-0.43955226841481043,-1.2302452877439438,-1.3821290912760622,-1.02342381486338,2.9944511899123603,0.8843253753961765,1.8906694939515276,1.5809220421218821,-0.7528450205022053,0.2786781386912482,0.7518164632462099,-0.36020808645859054,3.067214874831629,1.369980905900342,-0.07711309132908688,-0.05196213624197448,1.1944311691364766,2.8134730400382506,2.9618780425769327,1.5212977725567718,0.8733798938179188,0.04770930716017372,1.4309005541628823,0.6620352061775991,2.6449491417397626
| 3,120
|
Cholesterol binding
| 7
| 13
| 2.879326
| 0.003985
|
Q14108,P45880,O15118,O94905,P30536,P21796,O95772
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
22,15,141,331,338,11,7
|
141,424,331,7,2152,11,870,338,888,15,842,22,1561
|
2.068372036315107,0.9496358869067834,1.1944311691364766,3.1073290564690894,-0.4795833493036897,3.1073290564690894,0.32631335668396794,1.1839656140069246,0.314435910199321,3.1073290564690894,0.35000601574553336,3.1073290564690894,-0.1786726765570447
| 3,120
|
Protein transporter activity
| 9
| 13
| 2.876619
| 0.00402
|
Q15388,Q9NS69,Q9Y5J9,Q9HD20,P49755,Q07820,O14925,O60830,Q9UGP8
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
352,38,468,149,213,219,59,4,477
|
59,4,1449,502,213,2694,219,352,975,149,38,477,468
|
2.912744419090262,3.1073290564690894,-0.12770013664497198,0.8183900031612562,1.6302255513335107,-0.8229719076907467,1.6006849247164414,1.1419450738425903,0.21865884469902433,2.022036880868175,3.1073290564690894,0.8624169951839001,0.8843253753961765
| 3,120
|
Mental deterioration
| 33
| 102
| 2.872516
| 0.004072
|
Q9Y487,Q5XKP0,O15118,P04062,P35637,Q14108,O95169,Q13510,Q9UHD9,P50897,P21912,Q10713,P00846,Q9UQN3,O75503,P17900,O60313,P35670,Q9NZJ7,O43819,P21964,P00403,P20700,O43681,O95470,Q9NQZ5,P22626,O95140,O76024,P16278,Q9NPL8,P54802,P06865
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
130,132,141,275,405,22,292,21,294,16,178,54,61,451,64,68,203,342,216,217,92,94,478,486,105,234,496,495,244,117,245,119,252
|
1567,141,703,486,217,203,1652,2588,577,64,244,495,292,1338,105,502,94,61,552,1023,275,2553,566,252,608,1863,1528,1298,2666,1450,117,2438,68,478,178,92,496,2117,2847,2157,1718,405,342,741,2047,2237,2646,853,2423,16,2519,1970,1090,119,1361,2327,842,1344,2812,2027,1919,54,1239,1604,684,21,22,1132,2696,2596,132,2966,2381,1484,680,814,1684,1488,922,816,804,2248,1414,2215,776,1392,3045,1435,2385,1370,1436,245,234,2274,216,835,1962,294,1735,451,1995,130
|
-0.19147680577398604,2.068372036315107,0.5135807473198399,0.8404387020294766,1.6006849247164414,1.6498506656784873,-0.23003723432961226,-0.7528450205022053,0.6733223906940821,2.8632777541578998,1.5212977725567718,0.8294231843173793,1.3290708428266285,-0.06452581499784397,2.34913092241935,0.8183900031612562,2.4198350975517866,2.879803953814494,0.7294811048241373,0.17025670420391295,1.4005070484783886,-0.7250028020839093,0.6958411178937519,1.4912946822328113,0.628061558250135,-0.3339693636833012,-0.16589304761576545,-0.039421957943272905,-0.8088863866647676,-0.12770013664497198,2.241752275250984,-0.642176835766896,2.7800795662254263,0.8514366183973154,1.8049164509564872,2.4374031190390943,0.8294231843173793,-0.46621274973913956,-0.9799484723561187,-0.4795833493036897,-0.2688219354682781,0.9928354619075869,1.1734842794897706,0.4672450365868581,-0.42626214908149684,-0.5198580262786188,-0.7948310791463405,0.33817003194732587,-0.6284732846345887,3.1073290564690894,-0.6972780863213089,-0.38655086787023707,0.12150490797103468,2.2327310420192736,-0.07711309132908688,-0.5739422113824679,0.35000601574553336,-0.06452581499784397,-0.9367611784117341,-0.4129986202657584,-0.36020808645859054,2.9944511899123603,-0.0019414638218673386,-0.20430553885186603,0.5481269986020768,3.1073290564690894,3.1073290564690894,0.08470823190970675,-0.8229719076907467,-0.7528450205022053,2.141887659699094,-1.1853677536639942,-0.6011513795208029,-0.1404068795755925,0.5596036536159662,0.3853906088485544,-0.2429404073162766,-0.1404068795755925,0.2786781386912482,0.3853906088485544,0.3971446149576911,-0.5198580262786188,-0.10235882830439685,-0.5064058663136635,0.4322851425823638,-0.08972406297560863,-1.4594351482439722,-0.11501748631498755,-0.6011513795208029,-0.07711309132908688,-0.11501748631498755,1.5212977725567718,1.5611034542199569,-0.533337616964219,1.6105455839468559,0.3618213873624192,-0.37336641310163715,1.3290708428266285,-0.2688219354682781,0.9170579238372758,-0.38655086787023707,2.1510241118925633
| 3,120
|
membrane trafficking regulatory protein
| 7
| 18
| 2.861732
| 0.004213
|
Q14108,Q8WTV0,P13473,Q9P253,O43760,P11279,P24390
|
Functions
|
Panther Protein class
|
panther_protein_class
|
22,101,228,375,211,278,62
|
1696,2320,457,211,928,278,228,62,22,936,2211,101,1579,2104,1686,1184,1290,375
|
-0.2558686053497298,-0.5739422113824679,0.8952535006860544,1.6302255513335107,0.2667168001795272,1.3903464678842952,1.5710197329219444,2.879803953814494,3.1073290564690894,0.2667168001795272,-0.5064058663136635,2.3757265160314076,-0.19147680577398604,-0.4528690958405845,-0.2429404073162766,0.04770930716017372,-0.026905183599894182,1.0890591952246833
| 3,120
|
Transition metal ion transport
| 12
| 17
| 2.861235
| 0.00422
|
P98194,O75027,Q8N4V1,Q9H9B4,P02792,Q15043,Q04656,Q8TAD4,Q9HD20,P35670,P02786,Q15907
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
289,131,30,522,552,334,398,179,149,342,630,23
|
131,630,552,342,1302,289,2812,650,398,334,23,1754,30,179,2216,522,149
|
2.141887659699094,0.6053183644197377,0.7294811048241373,1.1734842794897706,-0.039421957943272905,1.3393208461533432,-0.9367611784117341,0.582499249500083,1.0143344206282272,1.1944311691364766,3.1073290564690894,-0.28180050541945734,3.1073290564690894,1.8049164509564872,-0.5064058663136635,0.7962704004189698,2.022036880868175
| 3,120
|
Intracellular protein transmembrane transport
| 11
| 21
| 2.859708
| 0.00424
|
Q9UGP8,Q15388,O75381,O95831,Q99442,Q3ZCQ8,O96008,Q15629,O14925,O60830,O75298
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
477,352,387,332,431,407,502,314,59,4,5
|
59,539,1624,4,5,387,1449,332,502,2153,663,2539,1951,2694,352,314,407,2169,431,1286,477
|
2.912744419090262,0.7518164632462099,-0.21715898005436454,3.1073290564690894,3.1073290564690894,1.04645811026075,-0.12770013664497198,1.1944311691364766,0.8183900031612562,-0.4795833493036897,0.5710610469198908,-0.7111258245859526,-0.37336641310163715,-0.8229719076907467,1.1419450738425903,1.2568960359855035,0.9928354619075869,-0.4795833493036897,0.9387936429122186,-0.026905183599894182,0.8624169951839001
| 3,120
|
Hydrolase activity hydrolyzing o glycosyl compounds
| 11
| 20
| 2.85736
| 0.004272
|
P06280,P08236,Q9NUJ1,P17900,Q9BTY2,P10253,P04062,P04066,P16278,P54802,P06865
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
159,353,133,68,300,365,275,237,117,119,252
|
452,906,275,237,159,252,608,353,365,117,68,3097,2745,119,1364,1875,667,300,133,1693
|
0.9061643301278702,0.29061838215713776,1.4005070484783886,1.54122881436266,1.9472674467092672,1.4912946822328113,0.628061558250135,1.1314000946481249,1.0996686756577085,2.241752275250984,2.7800795662254263,-1.927226968449506,-0.8796190081405505,2.2327310420192736,-0.07711309132908688,-0.3339693636833012,0.5710610469198908,1.3085255697617286,2.141887659699094,-0.2429404073162766
| 3,120
|
Carbohydrate derivative catabolic process
| 13
| 36
| 2.851772
| 0.004348
|
P06280,Q9NUJ1,P17900,Q9H773,Q9BTY2,P36639,P00813,P04062,P04066,P16278,P15586,P54802,P06865
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
159,133,68,266,300,140,78,275,237,117,246,119,252
|
808,1712,906,2949,2365,78,275,237,159,252,608,353,1530,246,117,68,2416,2956,3097,888,140,1836,811,2440,119,2028,1325,1017,1181,2011,300,692,3024,266,133,1494
|
0.3853906088485544,-0.2688219354682781,0.29061838215713776,-1.1556212409978055,-0.6011513795208029,2.687448357265577,1.4005070484783886,1.54122881436266,1.9472674467092672,1.4912946822328113,0.628061558250135,1.1314000946481249,-0.16589304761576545,1.5113109906247206,2.241752275250984,2.7800795662254263,-0.6284732846345887,-1.1704774288251414,-1.927226968449506,0.314435910199321,2.0776030242802497,-0.3208887425169809,0.3853906088485544,-0.642176835766896,2.2327310420192736,-0.4129986202657584,-0.05196213624197448,0.1823898035706314,0.04770930716017372,-0.3997615651907241,1.3085255697617286,0.5366310104853638,-1.3514648583892033,1.4309005541628823,2.141887659699094,-0.1404068795755925
| 3,120
|
Disproportionate short stature
| 10
| 24
| 2.84123
| 0.004494
|
Q7LGA3,Q7RTS9,Q32P28,Q9H6U8,Q9UHX1,Q15392,P16278,O00116,Q9BV10,Q96MF7
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
27,196,232,363,240,402,117,368,346,288
|
368,1941,2920,578,1450,117,2183,1998,919,1540,708,2076,402,232,1244,27,196,1727,427,288,346,363,1588,240
|
1.0890591952246833,-0.37336641310163715,-1.081846393052922,0.6733223906940821,-0.12770013664497198,2.241752275250984,-0.4929810145479234,-0.3997615651907241,0.2786781386912482,-0.16589304761576545,0.5135807473198399,-0.43955226841481043,1.0035932957279798,1.5611034542199569,-0.0019414638218673386,3.1073290564690894,1.6889376731850534,-0.2688219354682781,0.9496358869067834,1.3495558255696736,1.1629871131431153,1.11026194950554,-0.19147680577398604,1.54122881436266
| 3,120
|
Sphingolipid biosynthetic process
| 7
| 15
| 2.830131
| 0.004653
|
Q99805,Q13510,Q9P035,O95470,Q53H12,P04062,O15269
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
197,21,326,105,171,275,280
|
981,280,1767,105,275,2608,2028,401,21,171,1076,197,2089,326,1290
|
0.20659078834565117,1.3801711028302934,-0.29480442366640136,2.34913092241935,1.4005070484783886,-0.7668105367504043,-0.4129986202657584,1.0035932957279798,3.1073290564690894,1.8811924590596094,0.13372594148942707,1.6889376731850534,-0.43955226841481043,1.215315149662245,-0.026905183599894182
| 3,120
|
Mitochondrial complex i assembly model oxphos system
| 11
| 28
| 2.813542
| 0.0049
|
Q9BQ95,O95169,Q9BUB7,Q9P0J0,Q96CU9,Q9Y6M9,O96000,Q9NPL8,Q9NX14,O95168,Q8IUX1
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
550,292,493,143,48,80,180,245,470,376,223
|
2718,1569,577,1423,1127,376,292,1192,2017,180,1023,2199,2071,2984,1655,1075,1029,223,48,550,1370,493,1043,245,470,1186,143,80
|
-0.8512341644014038,-0.19147680577398604,0.6733223906940821,-0.11501748631498755,0.08470823190970675,1.0784334535521216,1.3290708428266285,0.03533096386757563,-0.4129986202657584,1.795323913719972,0.17025670420391295,-0.5064058663136635,-0.43955226841481043,-1.2302452877439438,-0.23003723432961226,0.13372594148942707,0.17025670420391295,1.5809220421218821,3.067214874831629,0.7406578703701303,-0.07711309132908688,0.8404387020294766,0.158101752015416,1.5212977725567718,0.8733798938179188,0.04770930716017372,2.068372036315107,2.6449491417397626
| 3,120
|
Establishment of protein localization to membrane
| 36
| 91
| 2.798822
| 0.005129
|
Q9BZG1,Q8N4V1,Q15006,P61026,O15118,Q9NS69,Q9P0J0,Q9NPA0,Q9HD20,Q15041,Q15907,P98194,Q9H6R6,Q53H12,P43307,Q9UNL2,Q99442,P40855,Q4J6C6,Q5BJH7,Q15629,Q15904,Q9Y512,Q15070,Q9GZY8,O00560,O43765,Q9Y5J9,Q9H4A6,Q9UGP8,O14737,O43681,O60725,Q9Y276,P46379,Q96A33
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
392,30,518,516,141,38,143,277,149,279,23,289,297,171,14,433,431,436,569,183,314,192,323,77,336,457,584,468,214,477,485,486,107,241,497,125
|
2606,2512,457,485,1050,141,2662,486,584,107,2567,2987,1449,1169,661,1715,1674,2307,2119,663,2202,1917,436,1967,14,497,1835,1572,954,1950,2539,2026,1951,516,2694,3057,289,2801,1198,2400,1636,518,279,1810,77,314,192,23,569,171,183,689,3101,2169,2334,30,860,975,764,125,2215,431,1120,392,336,1786,1285,1438,214,297,1852,598,149,277,1217,38,2387,1205,143,477,1883,2548,1938,2110,433,1033,241,962,323,468,2016
|
-0.7668105367504043,-0.6972780863213089,0.8952535006860544,0.8404387020294766,0.1459248602176856,2.068372036315107,-0.8088863866647676,0.8404387020294766,0.6620352061775991,2.3402438064667255,-0.7389091550000886,-1.2452739049804467,-0.12770013664497198,0.04770930716017372,0.5710610469198908,-0.2688219354682781,-0.2429404073162766,-0.5603795848494529,-0.46621274973913956,0.5710610469198908,-0.5064058663136635,-0.36020808645859054,0.927934341607611,-0.38655086787023707,3.1073290564690894,0.8294231843173793,-0.3208887425169809,-0.19147680577398604,0.24273050882000022,-0.37336641310163715,-0.7111258245859526,-0.4129986202657584,-0.37336641310163715,0.7962704004189698,-0.8229719076907467,-1.5062692780273925,1.3393208461533432,-0.9224287018087298,0.03533096386757563,-0.6147981757408897,-0.21715898005436454,0.7962704004189698,1.3903464678842952,-0.30783379939432337,2.695918388459061,1.2568960359855035,1.7471650667426148,3.1073290564690894,0.6958411178937519,1.8811924590596094,1.7664679945101098,0.5366310104853638,-2.0797011567697794,-0.4795833493036897,-0.5739422113824679,3.1073290564690894,0.33817003194732587,0.21865884469902433,0.44395840998636554,2.187453572170523,-0.5064058663136635,0.9387936429122186,0.09699614240690609,1.04645811026075,1.1944311691364766,-0.29480442366640136,-0.026905183599894182,-0.11501748631498755,1.620392445349469,1.318805766980325,-0.3208887425169809,0.6507293845573393,2.022036880868175,1.4005070484783886,0.022929782979047558,3.1073290564690894,-0.6011513795208029,0.03533096386757563,2.068372036315107,0.8624169951839001,-0.3339693636833012,-0.7111258245859526,-0.36020808645859054,-0.4528690958405845,0.9387936429122186,0.17025670420391295,1.54122881436266,0.24273050882000022,1.2257336786097104,0.8843253753961765,-0.3997615651907241
| 3,120
|
The citric acid tca cycle and respiratory electron transport
| 34
| 98
| 2.787835
| 0.005306
|
Q16134,Q9H9P8,Q9P0J0,P35613,Q9UDW1,Q9Y6N1,O75880,O14949,P21796,O75964,Q9BQ95,P13073,P24539,O95169,P14927,Q86Y39,P09669,P21912,O96000,P00846,P20674,P06576,P22695,Q9Y6M9,Q9NX14,O43819,P56385,P00403,Q8IUX1,P09622,Q13423,Q96I36,Q9NPL8,O95168
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
519,527,143,145,42,404,273,1,11,6,550,9,12,292,293,170,561,178,180,61,66,458,205,80,470,217,348,94,223,354,103,504,245,376
|
3107,1168,744,995,1,2718,2535,217,1525,1569,1770,577,1423,2832,1127,273,660,6,376,292,1192,2017,1143,180,2869,94,61,1023,458,2945,1673,1997,965,354,561,2666,1256,1299,9,2391,293,1145,2199,66,11,178,205,2366,12,1273,2071,2157,1359,145,801,1804,2236,2537,2237,1320,1999,2860,2122,2984,2573,1655,2124,1106,1479,348,2710,2965,1175,103,770,717,519,1075,1407,2079,1029,170,223,504,2061,2804,550,1370,1043,527,245,470,1186,143,1990,42,80,404
|
-2.3244806247371206,0.04770930716017372,0.45561168292170245,0.19450113637357203,3.1073290564690894,-0.8512341644014038,-0.7111258245859526,1.6006849247164414,-0.16589304761576545,-0.19147680577398604,-0.29480442366640136,0.6733223906940821,-0.11501748631498755,-0.9655209099750421,0.08470823190970675,1.4005070484783886,0.5710610469198908,3.1073290564690894,1.0784334535521216,1.3290708428266285,0.03533096386757563,-0.4129986202657584,0.07239784971023856,1.795323913719972,-1.0088997675803657,2.4198350975517866,2.879803953814494,0.17025670420391295,0.8952535006860544,-1.140799018459453,-0.2429404073162766,-0.3997615651907241,0.23070539012934577,1.1314000946481249,0.7070727943770848,-0.8088863866647676,-0.014411717321070097,-0.039421957943272905,3.1073290564690894,-0.6147981757408897,1.3290708428266285,0.07239784971023856,-0.5064058663136635,2.7884423176310245,3.1073290564690894,1.8049164509564872,1.6498506656784873,-0.6011513795208029,3.1073290564690894,-0.026905183599894182,-0.43955226841481043,-0.4795833493036897,-0.07711309132908688,2.031328055456678,0.3971446149576911,-0.30783379939432337,-0.5198580262786188,-0.7111258245859526,-0.5198580262786188,-0.05196213624197448,-0.3997615651907241,-0.9944080393492227,-0.46621274973913956,-1.2302452877439438,-0.7389091550000886,-0.23003723432961226,-0.46621274973913956,0.10926167126011344,-0.1404068795755925,1.1524740622552163,-0.837087785495116,-1.1853677536639942,0.04770930716017372,2.358007059486536,0.4322851425823638,0.5020263274235438,0.7962704004189698,0.13372594148942707,-0.10235882830439685,-0.43955226841481043,0.17025670420391295,1.8906694939515276,1.5809220421218821,0.8183900031612562,-0.42626214908149684,-0.9224287018087298,0.7406578703701303,-0.07711309132908688,0.158101752015416,0.7851838529268446,1.5212977725567718,0.8733798938179188,0.04770930716017372,2.068372036315107,-0.38655086787023707,3.1073290564690894,2.6449491417397626,1.0035932957279798
| 3,120
|
Glycoside hydrolase superfamily [IPR017853]
| 8
| 15
| 2.787439
| 0.005313
|
P06280,P08236,Q9BTY2,P04066,P04062,P16278,P54802,P06865
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
159,353,300,237,275,117,119,252
|
906,275,237,159,252,608,675,353,365,117,2745,119,1875,300,1203
|
0.29061838215713776,1.4005070484783886,1.54122881436266,1.9472674467092672,1.4912946822328113,0.628061558250135,0.5596036536159662,1.1314000946481249,1.0996686756577085,2.241752275250984,-0.8796190081405505,2.2327310420192736,-0.3339693636833012,1.3085255697617286,0.03533096386757563
| 3,120
|
Hydrolase activity acting on glycosyl bonds
| 12
| 27
| 2.784269
| 0.005365
|
P06280,O75503,P08236,Q9NUJ1,P17900,Q9BTY2,P10253,P04062,P04066,P16278,P54802,P06865
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
159,64,353,133,68,300,365,275,237,117,119,252
|
1022,452,906,64,275,237,159,252,608,353,365,2232,1530,117,68,1381,2954,2368,3097,2745,119,1364,1875,667,300,133,1693
|
0.17025670420391295,0.9061643301278702,0.29061838215713776,2.8632777541578998,1.4005070484783886,1.54122881436266,1.9472674467092672,1.4912946822328113,0.628061558250135,1.1314000946481249,1.0996686756577085,-0.5198580262786188,-0.16589304761576545,2.241752275250984,2.7800795662254263,-0.08972406297560863,-1.1704774288251414,-0.6011513795208029,-1.927226968449506,-0.8796190081405505,2.2327310420192736,-0.07711309132908688,-0.3339693636833012,0.5710610469198908,1.3085255697617286,2.141887659699094,-0.2429404073162766
| 3,120
|
Electron transport chain
| 20
| 71
| 2.778076
| 0.005468
|
Q9P0J0,P04062,Q9UDW1,Q9Y6N1,O14949,Q7KZN9,P13073,O95169,P14927,P16435,P21912,O96000,Q9UJS0,P20674,Q9Y6M9,O43819,P00403,P09622,Q9H3K2,O95168
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
143,275,42,404,1,151,9,292,293,298,178,180,311,66,80,217,94,354,367,376
|
3107,744,995,1,981,926,2845,2718,217,1525,1569,1770,577,1423,1127,425,376,292,1192,2017,180,2257,94,1023,275,1887,2019,767,965,1528,354,1256,2260,9,2391,1888,293,2781,1145,298,2199,66,178,2366,2094,2071,2235,2157,2236,714,1320,2860,2984,1655,1405,1606,519,1075,1407,1975,151,3045,2998,2216,367,777,143,42,311,80,404
|
-2.3244806247371206,0.45561168292170245,0.19450113637357203,3.1073290564690894,0.20659078834565117,0.2667168001795272,-0.9799484723561187,-0.8512341644014038,1.6006849247164414,-0.16589304761576545,-0.19147680577398604,-0.29480442366640136,0.6733223906940821,-0.11501748631498755,0.08470823190970675,0.9496358869067834,1.0784334535521216,1.3290708428266285,0.03533096386757563,-0.4129986202657584,1.795323913719972,-0.533337616964219,2.4198350975517866,0.17025670420391295,1.4005070484783886,-0.34707577428405895,-0.4129986202657584,0.4322851425823638,0.23070539012934577,-0.16589304761576545,1.1314000946481249,-0.014411717321070097,-0.533337616964219,3.1073290564690894,-0.6147981757408897,-0.34707577428405895,1.3290708428266285,-0.9081276149528227,0.07239784971023856,1.3085255697617286,-0.5064058663136635,2.7884423176310245,1.8049164509564872,-0.6011513795208029,-0.4528690958405845,-0.43955226841481043,-0.5198580262786188,-0.4795833493036897,-0.5198580262786188,0.5020263274235438,-0.05196213624197448,-0.9944080393492227,-1.2302452877439438,-0.23003723432961226,-0.10235882830439685,-0.20430553885186603,0.7962704004189698,0.13372594148942707,-0.10235882830439685,-0.38655086787023707,2.003418073325324,-1.4594351482439722,-1.2754363677556144,-0.5064058663136635,1.0996686756577085,0.4322851425823638,2.068372036315107,3.1073290564690894,1.2672525814950062,2.6449491417397626,1.0035932957279798
| 3,120
|
Serine hydrolase activity
| 8
| 18
| 2.777382
| 0.00548
|
O14773,Q9H3G5,Q9H300,P42785,P10619,O75976,Q9HB40,Q5JRX3
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
0,70,269,46,91,400,50,254
|
0,703,400,91,2043,2836,1803,46,2421,1278,782,439,569,254,1725,269,70,50
|
3.1073290564690894,0.5135807473198399,1.0035932957279798,2.4374031190390943,-0.42626214908149684,-0.9655209099750421,-0.30783379939432337,3.083286891375091,-0.6284732846345887,-0.026905183599894182,0.42059180507154753,0.927934341607611,0.6958411178937519,1.4912946822328113,-0.2688219354682781,1.4207840447832099,2.7800795662254263,3.034964700499758
| 3,120
|
Protein insertion into membrane
| 14
| 28
| 2.777377
| 0.00548
|
O14737,Q8N4V1,O43681,Q53H12,Q15070,Q9NS69,Q9P0J0,Q9Y276,Q9NPA0,P46379,Q9Y5J9,Q15629,Q96A33,Q9Y512
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
485,30,486,171,77,38,143,241,277,497,468,314,125,323
|
485,2662,486,584,1449,1715,2307,2202,497,2694,518,77,314,171,689,3101,30,860,764,125,277,38,1205,143,241,323,468,2016
|
0.8404387020294766,-0.8088863866647676,0.8404387020294766,0.6620352061775991,-0.12770013664497198,-0.2688219354682781,-0.5603795848494529,-0.5064058663136635,0.8294231843173793,-0.8229719076907467,0.7962704004189698,2.695918388459061,1.2568960359855035,1.8811924590596094,0.5366310104853638,-2.0797011567697794,3.1073290564690894,0.33817003194732587,0.44395840998636554,2.187453572170523,1.4005070484783886,3.1073290564690894,0.03533096386757563,2.068372036315107,1.54122881436266,1.2257336786097104,0.8843253753961765,-0.3997615651907241
| 3,120
|
Monovalent inorganic cation homeostasis
| 18
| 30
| 2.757055
| 0.005832
|
P05026,O75503,Q9Y487,P0CG08,P04899,Q05086,P27361,Q92544,P05023,P50897,Q9Y5X3,P06576,P54709,O75787,P51790,Q93050,Q9Y6M7,Q15904
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
661,64,130,639,705,479,740,621,201,16,235,458,748,501,369,88,506,192
|
64,501,964,705,201,661,458,639,740,1383,16,954,369,748,783,1871,479,192,621,88,2104,960,1120,1081,2548,1618,130,235,3098,506
|
2.8632777541578998,0.8183900031612562,0.23070539012934577,0.5135807473198399,1.6596427578574324,0.5710610469198908,0.8952535006860544,0.593918331939264,0.4672450365868581,-0.08972406297560863,3.1073290564690894,0.24273050882000022,1.0890591952246833,0.45561168292170245,0.42059180507154753,-0.3339693636833012,0.8514366183973154,1.7471650667426148,0.6166994167264761,2.5246065738795194,-0.4528690958405845,0.24273050882000022,0.09699614240690609,0.13372594148942707,-0.7111258245859526,-0.20430553885186603,2.1510241118925633,1.5611034542199569,-1.9945391164615682,0.8183900031612562
| 3,120
|
Mib complex
| 8
| 10
| 2.755735
| 0.005856
|
Q6UXV4,Q5XKP0,Q9BUR5,O75431,Q16891,Q13505,Q9NX63,Q9Y512
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
195,132,165,357,210,52,443,323
|
357,1475,52,210,132,195,165,542,443,323
|
1.120839071139155,-0.1404068795755925,3.026879918923703,1.640044944107091,2.141887659699094,1.6986756619645358,1.9095856653720285,0.7518164632462099,0.927934341607611,1.2257336786097104
| 3,120
|
Subsets and Splits
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