term
stringlengths
2
121
overlap
int64
6
281
setsize
int64
7
499
score
float64
1.96
10.6
pval
float64
0
0.05
edge
stringlengths
41
1.97k
type
stringclasses
5 values
subtype
stringclasses
24 values
subtype_key
stringclasses
24 values
edge_idxs
stringlengths
11
1.17k
ann_idxs
stringlengths
19
2.31k
ann_vals
stringlengths
124
9.94k
sig_size
int64
2.2k
3.73k
Transporter
58
196
3.777483
0.000158
Q8IXU6,Q86VD7,Q96EE3,Q9UIA9,O60499,O43772,Q9UBX3,Q9BSK2,Q9P2W9,P50542,O43760,P28288,O60645,Q93050,Q9NRW7,P00846,Q9H2J7,O14617,P11166,P53007,P12236,Q99805,Q9HD45,P61421,Q15388,Q9HC07,Q15833,Q13190,Q9Y6C9,P08183,Q12768,P12235,Q9HC21,Q9P253,P56134,Q12769,Q7L0J3,P21281,Q9Y619,Q8TEX9,Q9H2D1,P30825,Q00325,Q9C0E2,Q96K37,Q9NUT2,Q92544,Q9BQT8,P53621,Q9Y296,Q9UI12,Q6N075,Q03518,Q70HW3,Q9Y678,P49257,O95563,Q15070
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
5,133,669,406,16,15,144,18,150,522,270,653,646,155,549,156,546,645,651,162,541,36,163,287,288,302,175,296,584,53,181,54,192,457,561,562,69,446,475,605,81,85,598,218,217,495,356,490,595,497,235,361,111,242,517,621,616,378
2021,1947,858,2260,1476,1708,1949,645,1221,1360,2497,1709,2023,270,15,1314,16,646,2934,2150,1952,1845,1022,1654,1847,3146,982,2027,1024,2371,1959,1062,616,3060,1264,156,2461,2619,865,3134,53,2373,2914,1320,651,2105,54,541,1064,2034,1541,446,1857,2109,3037,653,2858,85,1325,3093,2916,2467,1428,1430,1864,1431,621,2044,522,2220,2771,793,719,162,1967,595,2772,657,1379,2045,1733,2168,561,2474,1734,287,1383,2862,3136,2382,2383,598,1037,2671,1280,111,2514,1073,181,562,2284,2286,296,2229,2631,1673,2595,1334,378,2775,1563,2389,288,2557,175,2842,1291,361,1614,1919,1747,3312,242,69,2805,133,1821,5,1509,1202,1340,762,2719,605,2846,1619,356,1398,155,730,669,217,1760,842,1051,1516,2563,36,490,2195,18,2813,218,3140,2012,81,546,809,1518,930,1884,302,192,163,1253,549,495,1699,2965,772,3156,2144,457,150,1582,773,144,235,406,2205,3195,2820,1639,2904,497,2364,3031,1258,741,2694,818,1946,475,517,584,1586
-0.1983298434546702,-0.16915765752368028,0.41965586752605055,-0.3160348969490162,0.060467414101225296,-0.05350303097992167,-0.16915765752368028,0.5801743268480191,0.2005724364337766,0.11681693759758847,-0.4654106405661174,-0.05350303097992167,-0.1983298434546702,1.144456813443884,3.697871107665648,0.14483658048926837,3.697871107665648,0.5801743268480191,-0.8650123589926522,-0.2569802644281954,-0.16915765752368028,-0.11112230190969725,0.31086666228014365,-0.024850986633067236,-0.11112230190969725,-1.2475690670035406,0.33820212925301407,-0.1983298434546702,0.31086666228014365,-0.3754892338100565,-0.16915765752368028,0.28343716336325137,0.6066297150102449,-1.0546965194844964,0.17275463656922826,1.6293092873800175,-0.43533889653030694,-0.5562072945734238,0.41965586752605055,-1.2152058878452634,2.5792918852390194,-0.3754892338100565,-0.8337145938116572,0.14483658048926837,0.5801743268480191,-0.2276042406016599,2.5792918852390194,0.6855048182603979,0.28343716336325137,-0.1983298434546702,0.03213471430384632,0.8153801473078209,-0.11112230190969725,-0.2276042406016599,-1.0228587054425817,0.5801743268480191,-0.771394044942476,2.2270083787382036,0.14483658048926837,-1.1186374013991909,-0.8337145938116572,-0.43533889653030694,0.08869434652356714,0.08869434652356714,-0.11112230190969725,0.08869434652356714,0.6066297150102449,-0.1983298434546702,0.7116358722612617,-0.28645733903368353,-0.6786074245996516,0.47350891704813686,0.5270123572912739,1.5818838811891258,-0.16915765752368028,0.6330026427578571,-0.6786074245996516,0.5801743268480191,0.11681693759758847,-0.1983298434546702,-0.05350303097992167,-0.2569802644281954,0.6592940398904245,-0.43533889653030694,-0.05350303097992167,1.0945945877969334,0.11681693759758847,-0.771394044942476,-1.2152058878452634,-0.3754892338100565,-0.3754892338100565,0.6330026427578571,0.31086666228014365,-0.5866649642761562,0.17275463656922826,2.0010668397853175,-0.4654106405661174,0.28343716336325137,1.5103236781354623,0.6592940398904245,-0.3160348969490162,-0.3160348969490162,1.0695626309218393,-0.28645733903368353,-0.5562072945734238,-0.024850986633067236,-0.5258453497283577,0.14483658048926837,0.91791615126421,-0.6786074245996516,0.03213471430384632,-0.3754892338100565,1.0945945877969334,-0.49557962951464074,1.5342340098871912,-0.74037215539053,0.17275463656922826,0.9433672737733582,0.0036951455715587326,-0.14008827619228245,-0.05350303097992167,-2.083747233101994,1.2679658226874506,2.4484530262047968,-0.7094431280794159,1.8168408195595176,-0.08226034641678645,4.469891478838932,0.060467414101225296,0.22829128088385117,0.14483658048926837,0.5003038219140473,-0.6172178657741221,0.6330026427578571,-0.74037215539053,0.0036951455715587326,0.9687467516697891,0.11681693759758847,1.6529390108089894,0.5270123572912739,0.5801743268480191,1.3413095590408202,-0.05350303097992167,0.44662661518260455,0.31086666228014365,0.060467414101225296,-0.49557962951464074,3.0262046723466742,0.7636623002448963,-0.2569802644281954,3.6780129047155596,-0.7094431280794159,1.3413095590408202,-1.2152058878452634,-0.16915765752368028,2.2716465763795988,0.6855048182603979,0.47350891704813686,0.060467414101225296,0.39259560337501387,-0.11112230190969725,1.0695626309218393,1.4623297140439213,1.5818838811891258,0.2005724364337766,0.6855048182603979,0.7636623002448963,-0.024850986633067236,-0.8964011979097756,0.5003038219140473,-1.2475690670035406,-0.2276042406016599,0.8153801473078209,1.700034827064007,0.03213471430384632,0.5003038219140473,1.7235018312297918,1.292476019958997,0.8923926409127418,-0.2569802644281954,-1.3451743358044173,-0.7094431280794159,0.0036951455715587326,-0.8025083410499405,0.7636623002448963,-0.34571237893882045,-0.9911098512078583,0.2005724364337766,0.5270123572912739,-0.5866649642761562,0.47350891704813686,-0.14008827619228245,0.7895593798784971,0.7376880792986121,0.6592940398904245,0.03213471430384632
3,375
Anion transmembrane transporter activity
25
48
3.751311
0.000176
Q86VD7,Q8TDW0,Q9UBX3,P21796,Q9Y277,P11166,P53007,P12236,P53985,P51798,P12235,O43681,Q9HC21,P45880,Q9Y619,Q9H2D1,Q9C0H2,P30825,P0CG08,Q14728,Q9BQT8,Q6N075,Q4KMQ2,Q9Y696,O95563
Functions
GO Molecular function
msigdb_gomf
133,530,144,24,552,651,162,541,657,180,54,683,192,62,475,81,80,85,340,355,490,361,360,776,616
898,2539,1709,683,1314,1847,616,865,2373,340,651,54,541,24,85,1430,62,180,162,657,2168,1280,355,2557,360,1291,361,1614,1747,133,762,530,1760,3222,490,80,81,930,1884,192,1310,144,2205,552,2904,475,776,1586
0.39259560337501387,-0.49557962951464074,-0.05350303097992167,0.5536355300185024,0.14483658048926837,-0.11112230190969725,0.6066297150102449,0.41965586752605055,-0.3754892338100565,0.9940553151106681,0.5801743268480191,2.5792918852390194,0.6855048182603979,3.356198648789754,2.2270083787382036,0.08869434652356714,2.514056875953885,1.5103236781354623,1.5818838811891258,0.5801743268480191,-0.2569802644281954,0.17275463656922826,0.9687467516697891,-0.49557962951464074,0.9433672737733582,0.17275463656922826,0.9433672737733582,0.0036951455715587326,-0.05350303097992167,1.8168408195595176,0.5003038219140473,0.7116358722612617,-0.05350303097992167,-1.4435454454021128,0.7636623002448963,2.2716465763795988,2.2716465763795988,0.39259560337501387,-0.11112230190969725,1.4623297140439213,0.17275463656922826,1.7235018312297918,-0.2569802644281954,0.6855048182603979,-0.8025083410499405,0.7895593798784971,0.5003038219140473,0.03213471430384632
3,375
SLC superfamily of solute carriers
23
48
3.718061
0.000201
Q8IXU6,Q86VD7,O43772,Q9UBX3,Q9BSK2,Q9H2J7,P11166,P53007,P12236,Q9HC07,Q9Y6C9,P12235,Q9HC21,Q7L0J3,Q9Y619,Q9H2D1,P30825,Q96K37,Q00325,Q9BQT8,Q6N075,Q70HW3,O95563
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
5,133,15,144,18,546,651,162,541,302,584,54,192,69,475,81,85,217,598,490,361,242,616
15,1314,1847,2027,616,865,2373,651,54,541,85,1430,162,657,2168,598,1280,2557,1291,361,1614,1747,3312,242,69,133,5,762,1619,217,1760,490,18,3140,81,546,809,930,1884,302,192,772,144,2205,2904,475,584,1586
3.697871107665648,0.14483658048926837,-0.11112230190969725,-0.1983298434546702,0.6066297150102449,0.41965586752605055,-0.3754892338100565,0.5801743268480191,2.5792918852390194,0.6855048182603979,2.2270083787382036,0.08869434652356714,1.5818838811891258,0.5801743268480191,-0.2569802644281954,0.6330026427578571,0.17275463656922826,-0.49557962951464074,0.17275463656922826,0.9433672737733582,0.0036951455715587326,-0.05350303097992167,-2.083747233101994,1.2679658226874506,2.4484530262047968,1.8168408195595176,4.469891478838932,0.5003038219140473,0.0036951455715587326,1.3413095590408202,-0.05350303097992167,0.7636623002448963,3.6780129047155596,-1.2152058878452634,2.2716465763795988,0.6855048182603979,0.47350891704813686,0.39259560337501387,-0.11112230190969725,1.0695626309218393,1.4623297140439213,0.5003038219140473,1.7235018312297918,-0.2569802644281954,-0.8025083410499405,0.7895593798784971,0.6592940398904245,0.03213471430384632
3,375
Ion transmembrane transport
61
167
3.697104
0.000218
P50570,Q13546,Q13642,P78417,Q86VD7,Q8TDW0,Q8N4V1,Q9Y4C2,O43772,Q9UBX3,O75964,P21796,Q9Y277,P00846,Q9H2J7,Q6P4Q7,O43865,P53007,P12236,P61421,P00403,Q9HC07,P42858,P05067,Q13423,P08183,Q6P4A7,P46939,P12235,P51798,Q9HC21,P45880,Q9NRA0,P56134,P46934,P21281,Q9Y619,Q9H2D1,Q9C0H2,Q9HD20,Q14847,Q9UDW1,Q96GC9,P30825,Q9HD26,O75844,Q00535,Q00325,P0CG08,Q9NUT2,P13073,Q14728,Q9BQT8,Q9UI12,Q9UHD1,P27105,Q4KMQ2,Q9UHG3,Q70HW3,O95563,P07384
Processes and pathways
GO Biological process
msigdb_gobp
503,626,627,374,133,530,11,681,15,144,393,24,552,156,546,159,161,162,541,287,538,302,167,166,435,53,568,560,54,180,192,62,193,561,447,446,475,81,80,209,600,471,84,85,610,88,599,598,340,495,591,355,490,235,369,479,360,113,242,616,123
898,3288,2087,2697,2539,1709,1710,15,1314,161,1479,1416,1022,1591,1365,1787,1847,88,2542,3146,393,2027,616,1370,538,156,2461,2619,166,865,2734,3134,2953,123,2031,53,2373,1063,340,3227,2424,1657,54,541,591,1064,870,1794,3293,1541,1797,446,1857,1490,24,2109,3037,479,946,1800,1545,2882,85,1033,3093,2039,2916,2859,1428,1430,167,62,447,560,3018,3135,503,180,162,657,2802,2045,2168,561,2474,287,1383,2710,374,2383,598,599,1280,1912,2744,2922,2630,435,626,627,355,600,1288,1563,3046,2557,2185,360,1291,568,159,3312,1239,242,1920,133,2981,3107,11,3051,1823,762,530,1005,1927,84,2526,1760,2006,3203,1091,1626,490,3099,3357,80,3140,3274,81,546,849,930,1884,302,192,209,610,193,495,675,1310,144,471,369,113,235,2205,2729,3109,552,2904,2905,681,2018,475,776,1586
0.39259560337501387,-1.844498937224531,-0.2276042406016599,-0.6172178657741221,-0.49557962951464074,-0.05350303097992167,-0.05350303097992167,3.697871107665648,0.14483658048926837,1.5818838811891258,0.060467414101225296,0.08869434652356714,0.31086666228014365,0.0036951455715587326,0.11681693759758847,-0.08226034641678645,-0.11112230190969725,2.2046220417723954,-0.49557962951464074,-1.2475690670035406,0.8923926409127418,-0.1983298434546702,0.6066297150102449,0.11681693759758847,0.6855048182603979,1.6293092873800175,-0.43533889653030694,-0.5562072945734238,1.5580872461878,0.41965586752605055,-0.6478655125716591,-1.2152058878452634,-0.8964011979097756,1.8863015470497642,-0.1983298434546702,2.5792918852390194,-0.3754892338100565,0.28343716336325137,0.9940553151106681,-1.4765043166587404,-0.4053649182267038,-0.024850986633067236,2.5792918852390194,0.6855048182603979,0.6330026427578571,0.28343716336325137,0.41965586752605055,-0.08226034641678645,-1.9124600034874841,0.03213471430384632,-0.08226034641678645,0.8153801473078209,-0.11112230190969725,0.060467414101225296,3.356198648789754,-0.2276042406016599,-1.0228587054425817,0.7636623002448963,0.36544472945786843,-0.08226034641678645,0.03213471430384632,-0.8025083410499405,2.2270083787382036,0.31086666228014365,-1.1186374013991909,-0.1983298434546702,-0.8337145938116572,-0.771394044942476,0.08869434652356714,0.08869434652356714,1.5580872461878,2.514056875953885,0.8153801473078209,0.6592940398904245,-0.9911098512078583,-1.2152058878452634,0.7376880792986121,1.5103236781354623,1.5818838811891258,0.5801743268480191,-0.7094431280794159,-0.1983298434546702,-0.2569802644281954,0.6592940398904245,-0.43533889653030694,1.0945945877969334,0.11681693759758847,-0.6172178657741221,0.91791615126421,-0.3754892338100565,0.6330026427578571,0.6330026427578571,0.17275463656922826,-0.14008827619228245,-0.6478655125716591,-0.8337145938116572,-0.5562072945734238,0.8411254163810149,0.6066297150102449,0.6066297150102449,0.9687467516697891,0.6330026427578571,0.17275463656922826,0.03213471430384632,-1.0228587054425817,-0.49557962951464074,-0.2569802644281954,0.9433672737733582,0.17275463656922826,0.6592940398904245,1.6056244017080097,-2.083747233101994,0.2005724364337766,1.2679658226874506,-0.14008827619228245,1.8168408195595176,-0.9278806773204062,-1.150739668468142,3.9339465846713644,-1.0228587054425817,-0.08226034641678645,0.5003038219140473,0.7116358722612617,0.33820212925301407,-0.14008827619228245,2.249349781196953,-0.4654106405661174,-0.05350303097992167,-0.16915765752368028,-1.3778800978198302,0.28343716336325137,0.0036951455715587326,0.7636623002448963,-1.1186374013991909,-3.261532807782791,2.2716465763795988,-1.2152058878452634,-1.6760024115861647,2.2716465763795988,0.6855048182603979,0.44662661518260455,0.39259560337501387,-0.11112230190969725,1.0695626309218393,1.4623297140439213,1.3898977585599475,0.6330026427578571,1.4623297140439213,0.7636623002448963,0.5801743268480191,0.17275463656922826,1.7235018312297918,0.7895593798784971,0.9433672737733582,2.0010668397853175,1.292476019958997,-0.2569802644281954,-0.6172178657741221,-1.150739668468142,0.6855048182603979,-0.8025083410499405,-0.8025083410499405,0.5801743268480191,-0.16915765752368028,0.7895593798784971,0.5003038219140473,0.03213471430384632
3,375
Protein localization
24
76
3.670803
0.000242
O60830,Q13505,P49069,O43933,P50542,P21796,Q5JRX3,Q99595,Q9NS69,O14925,Q15388,Q10713,P50402,P05067,Q13190,P12235,Q93008,Q9NR77,P09601,Q9UJ83,P46379,Q9Y512,Q8N4H5,Q9BY49
Processes and pathways
Reactome Pathways
msigdb_reactome
0,8,272,145,522,24,281,28,29,284,288,414,413,166,296,54,452,61,68,473,91,371,485,385
1103,1648,284,1163,2418,2370,683,1951,1314,145,0,2910,2732,1787,1481,1847,2764,2153,1264,166,3134,1063,2580,68,3237,54,541,1539,24,1898,3037,653,1659,3148,826,91,272,413,522,1120,2167,1735,414,3084,296,8,799,288,881,281,1449,837,485,2239,1242,1341,452,3272,28,2296,1304,385,3077,61,29,2566,2144,473,2205,2206,1843,1585,371,2085,2788,3111
0.25591244186398043,-0.024850986633067236,1.0945945877969334,0.22829128088385117,-0.4053649182267038,-0.3754892338100565,0.5536355300185024,-0.16915765752368028,0.14483658048926837,1.700034827064007,6.177852396500397,-0.8337145938116572,-0.6478655125716591,-0.08226034641678645,0.060467414101225296,-0.11112230190969725,-0.6786074245996516,-0.2569802644281954,0.17275463656922826,1.5580872461878,-1.2152058878452634,0.28343716336325137,-0.5258453497283577,2.4703624293785205,-1.5095468498520557,2.5792918852390194,0.6855048182603979,0.03213471430384632,3.356198648789754,-0.14008827619228245,-1.0228587054425817,0.5801743268480191,-0.024850986633067236,-1.2475690670035406,0.44662661518260455,2.182190438903513,1.144456813443884,0.8667959860819097,0.7116358722612617,0.25591244186398043,-0.2569802644281954,-0.05350303097992167,0.8667959860819097,-1.0866228857275761,1.0695626309218393,4.204415092601044,0.47350891704813686,1.0945945877969334,0.41965586752605055,1.1195590959099642,0.08869434652356714,0.44662661518260455,0.7636623002448963,-0.28645733903368353,0.2005724364337766,0.14483658048926837,0.8153801473078209,-1.6760024115861647,3.294970582891578,-0.3160348969490162,0.17275463656922826,0.91791615126421,-1.0546965194844964,2.5358424878703127,3.2539898346567666,-0.49557962951464074,-0.2276042406016599,0.7895593798784971,-0.2569802644281954,-0.2569802644281954,-0.08226034641678645,0.03213471430384632,0.9433672737733582,-0.1983298434546702,-0.6786074245996516,-1.150739668468142
3,375
Ion transport
75
219
3.659078
0.000253
P50570,P17931,Q13546,Q13642,P78417,Q86VD7,Q8TDW0,Q8N4V1,Q9Y4C2,Q9NVV0,O43772,Q9UBX3,P20337,O75964,P21796,P28288,Q9Y277,P00846,Q9H2J7,Q6P4Q7,P11166,O43865,P12236,P53007,P53985,P00403,P61421,Q9HC07,P42858,P05067,Q13423,P08183,Q6P4A7,P46939,P12235,P51798,Q9HC21,P45880,Q9NRA0,P56134,Q7L0J3,O15173,P46934,P21281,Q9Y619,Q9H2D1,Q9C0H2,Q9HD20,Q14847,O75351,Q9UDW1,Q96GC9,P30825,Q9HD26,O75844,Q00535,Q00325,P0CG08,Q9NUT2,P13073,Q14728,Q9BQT8,Q9UI12,Q9UHD1,P27105,Q6N075,Q4KMQ2,P61201,Q9UHG3,Q70HW3,Q08209,O95563,P07384,Q13555,P14174
Processes and pathways
GO Biological process
msigdb_gobp
503,256,626,627,374,133,530,11,681,675,15,144,271,393,24,653,552,156,546,159,651,161,541,162,657,538,287,302,167,166,435,53,568,560,54,180,192,62,193,561,69,195,447,446,475,81,80,209,600,323,471,84,85,610,88,599,598,340,495,591,355,490,235,369,479,361,360,481,113,242,483,616,123,505,255
2021,898,3288,1475,2087,2697,2539,2657,819,195,1709,683,1710,15,1314,161,1479,1416,1022,1591,1365,323,1787,1847,88,2542,3146,393,822,2027,616,1370,1264,538,156,1113,2156,1319,2461,2619,166,865,2734,3134,2953,123,1420,2031,53,2373,1063,340,3227,2424,651,2270,1657,54,541,591,1855,255,1064,870,1794,256,3293,1541,271,1797,446,1857,1490,24,2109,1373,3037,479,946,1800,653,1545,1176,2882,85,1033,1547,1903,3093,2039,2916,2859,1428,1430,167,62,2471,447,560,3018,3135,503,180,2771,162,657,2802,2045,2168,561,2474,481,287,2920,1383,2710,374,2383,598,599,1037,2228,1280,1912,2744,483,3066,2922,2630,1038,435,626,505,627,355,600,1288,2556,1563,3046,2557,2482,2185,1237,360,1291,361,1614,1747,568,159,3312,1239,242,1920,69,133,2981,3107,11,3051,696,1823,762,530,1005,1619,1927,84,2526,1760,3222,2006,3203,1091,1626,490,3099,3357,80,2565,3140,3274,81,546,849,930,1884,302,192,209,610,193,495,675,1310,2965,772,144,471,369,113,1841,235,2205,2729,3301,3109,1522,2495,552,2904,2905,681,2018,1946,475,776,1586
-0.1983298434546702,0.39259560337501387,-1.844498937224531,0.060467414101225296,-0.2276042406016599,-0.6172178657741221,-0.49557962951464074,-0.5866649642761562,0.44662661518260455,1.4382450552811312,-0.05350303097992167,0.5536355300185024,-0.05350303097992167,3.697871107665648,0.14483658048926837,1.5818838811891258,0.060467414101225296,0.08869434652356714,0.31086666228014365,0.0036951455715587326,0.11681693759758847,1.0192936815049485,-0.08226034641678645,-0.11112230190969725,2.2046220417723954,-0.49557962951464074,-1.2475690670035406,0.8923926409127418,0.44662661518260455,-0.1983298434546702,0.6066297150102449,0.11681693759758847,0.17275463656922826,0.6855048182603979,1.6293092873800175,0.25591244186398043,-0.2569802644281954,0.14483658048926837,-0.43533889653030694,-0.5562072945734238,1.5580872461878,0.41965586752605055,-0.6478655125716591,-1.2152058878452634,-0.8964011979097756,1.8863015470497642,0.08869434652356714,-0.1983298434546702,2.5792918852390194,-0.3754892338100565,0.28343716336325137,0.9940553151106681,-1.4765043166587404,-0.4053649182267038,0.5801743268480191,-0.3160348969490162,-0.024850986633067236,2.5792918852390194,0.6855048182603979,0.6330026427578571,-0.11112230190969725,1.2187556408509548,0.28343716336325137,0.41965586752605055,-0.08226034641678645,1.2187556408509548,-1.9124600034874841,0.03213471430384632,1.144456813443884,-0.08226034641678645,0.8153801473078209,-0.11112230190969725,0.060467414101225296,3.356198648789754,-0.2276042406016599,0.11681693759758847,-1.0228587054425817,0.7636623002448963,0.36544472945786843,-0.08226034641678645,0.5801743268480191,0.03213471430384632,0.22829128088385117,-0.8025083410499405,2.2270083787382036,0.31086666228014365,0.03213471430384632,-0.14008827619228245,-1.1186374013991909,-0.1983298434546702,-0.8337145938116572,-0.771394044942476,0.08869434652356714,0.08869434652356714,1.5580872461878,2.514056875953885,-0.43533889653030694,0.8153801473078209,0.6592940398904245,-0.9911098512078583,-1.2152058878452634,0.7376880792986121,1.5103236781354623,-0.6786074245996516,1.5818838811891258,0.5801743268480191,-0.7094431280794159,-0.1983298434546702,-0.2569802644281954,0.6592940398904245,-0.43533889653030694,0.7636623002448963,1.0945945877969334,-0.8337145938116572,0.11681693759758847,-0.6172178657741221,0.91791615126421,-0.3754892338100565,0.6330026427578571,0.6330026427578571,0.31086666228014365,-0.28645733903368353,0.17275463656922826,-0.14008827619228245,-0.6478655125716591,0.7636623002448963,-1.0546965194844964,-0.8337145938116572,-0.5562072945734238,0.31086666228014365,0.8411254163810149,0.6066297150102449,0.7376880792986121,0.6066297150102449,0.9687467516697891,0.6330026427578571,0.17275463656922826,-0.49557962951464074,0.03213471430384632,-1.0228587054425817,-0.49557962951464074,-0.43533889653030694,-0.2569802644281954,0.2005724364337766,0.9433672737733582,0.17275463656922826,0.9433672737733582,0.0036951455715587326,-0.05350303097992167,0.6592940398904245,1.6056244017080097,-2.083747233101994,0.2005724364337766,1.2679658226874506,-0.14008827619228245,2.4484530262047968,1.8168408195595176,-0.9278806773204062,-1.150739668468142,3.9339465846713644,-1.0228587054425817,0.5536355300185024,-0.08226034641678645,0.5003038219140473,0.7116358722612617,0.33820212925301407,0.0036951455715587326,-0.14008827619228245,2.249349781196953,-0.4654106405661174,-0.05350303097992167,-1.4435454454021128,-0.16915765752368028,-1.3778800978198302,0.28343716336325137,0.0036951455715587326,0.7636623002448963,-1.1186374013991909,-3.261532807782791,2.2716465763795988,-0.49557962951464074,-1.2152058878452634,-1.6760024115861647,2.2716465763795988,0.6855048182603979,0.44662661518260455,0.39259560337501387,-0.11112230190969725,1.0695626309218393,1.4623297140439213,1.3898977585599475,0.6330026427578571,1.4623297140439213,0.7636623002448963,0.5801743268480191,0.17275463656922826,-0.8964011979097756,0.5003038219140473,1.7235018312297918,0.7895593798784971,0.9433672737733582,2.0010668397853175,-0.08226034641678645,1.292476019958997,-0.2569802644281954,-0.6172178657741221,-1.9465598176439003,-1.150739668468142,0.060467414101225296,-0.43533889653030694,0.6855048182603979,-0.8025083410499405,-0.8025083410499405,0.5801743268480191,-0.16915765752368028,-0.14008827619228245,0.7895593798784971,0.5003038219140473,0.03213471430384632
3,375
Ion transmembrane transporter activity
47
108
3.614626
0.000301
Q86VD7,Q8TDW0,Q8N4V1,Q9NVV0,O43772,Q9UBX3,O75964,P21796,Q9Y277,Q93050,P00846,Q9H2J7,Q6P4Q7,P11166,P53007,P12236,P61421,P53985,P00403,Q9HC07,Q13423,Q6P4A7,P12235,P51798,O43681,Q9HC21,P45880,P56134,P21281,Q9Y619,Q9H2D1,Q9C0H2,Q9HD20,Q14847,Q9UDW1,P30825,Q00535,Q00325,P0CG08,P13073,Q14728,Q9BQT8,Q9UI12,Q6N075,Q4KMQ2,Q70HW3,O95563
Functions
GO Molecular function
msigdb_gomf
133,530,11,675,15,144,393,24,552,155,156,546,159,651,162,541,287,657,538,302,435,568,54,180,683,192,62,561,446,475,81,80,209,600,471,85,599,598,340,591,355,490,235,361,360,242,616
898,2697,2539,1709,683,15,1314,1847,3146,393,2027,616,538,156,2461,2619,865,3134,2953,2031,2373,1063,340,2424,651,54,541,591,1064,1541,1797,446,1857,24,2109,3037,85,1033,3093,2916,2859,1428,1430,62,3018,3135,180,162,657,2168,561,2474,287,1383,2383,598,599,1280,435,355,600,3046,2557,360,1291,361,1614,1747,568,159,3312,242,1920,133,11,1823,762,530,1619,1927,155,1760,3222,490,3357,80,3140,81,546,930,1884,302,192,209,675,1310,144,471,235,2205,3109,552,2904,741,2694,475,776,1586
0.39259560337501387,-0.6172178657741221,-0.49557962951464074,-0.05350303097992167,0.5536355300185024,3.697871107665648,0.14483658048926837,-0.11112230190969725,-1.2475690670035406,0.8923926409127418,-0.1983298434546702,0.6066297150102449,0.6855048182603979,1.6293092873800175,-0.43533889653030694,-0.5562072945734238,0.41965586752605055,-1.2152058878452634,-0.8964011979097756,-0.1983298434546702,-0.3754892338100565,0.28343716336325137,0.9940553151106681,-0.4053649182267038,0.5801743268480191,2.5792918852390194,0.6855048182603979,0.6330026427578571,0.28343716336325137,0.03213471430384632,-0.08226034641678645,0.8153801473078209,-0.11112230190969725,3.356198648789754,-0.2276042406016599,-1.0228587054425817,2.2270083787382036,0.31086666228014365,-1.1186374013991909,-0.8337145938116572,-0.771394044942476,0.08869434652356714,0.08869434652356714,2.514056875953885,-0.9911098512078583,-1.2152058878452634,1.5103236781354623,1.5818838811891258,0.5801743268480191,-0.2569802644281954,0.6592940398904245,-0.43533889653030694,1.0945945877969334,0.11681693759758847,-0.3754892338100565,0.6330026427578571,0.6330026427578571,0.17275463656922826,0.8411254163810149,0.9687467516697891,0.6330026427578571,-1.0228587054425817,-0.49557962951464074,0.9433672737733582,0.17275463656922826,0.9433672737733582,0.0036951455715587326,-0.05350303097992167,0.6592940398904245,1.6056244017080097,-2.083747233101994,1.2679658226874506,-0.14008827619228245,1.8168408195595176,3.9339465846713644,-0.08226034641678645,0.5003038219140473,0.7116358722612617,0.0036951455715587326,-0.14008827619228245,1.6529390108089894,-0.05350303097992167,-1.4435454454021128,0.7636623002448963,-3.261532807782791,2.2716465763795988,-1.2152058878452634,2.2716465763795988,0.6855048182603979,0.39259560337501387,-0.11112230190969725,1.0695626309218393,1.4623297140439213,1.3898977585599475,0.5801743268480191,0.17275463656922826,1.7235018312297918,0.7895593798784971,1.292476019958997,-0.2569802644281954,-1.150739668468142,0.6855048182603979,-0.8025083410499405,0.5270123572912739,-0.5866649642761562,0.7895593798784971,0.5003038219140473,0.03213471430384632
3,375
Exopeptidase activity
10
32
3.601063
0.000317
Q9H3G5,Q9HB40,O14773,Q9NZ08,Q9UIQ6,P42785,P50579,Q7Z2K6,P55786,O75844
Functions
GO Molecular function
msigdb_gomf
66,67,188,204,100,10,77,116,22,88
188,88,587,1113,2269,196,1895,3039,1322,2884,10,77,22,916,754,2435,3234,116,484,1198,1204,1463,1138,1209,66,1305,67,1937,812,1152,204,100
1.4623297140439213,2.2046220417723954,0.6330026427578571,0.25591244186398043,-0.3160348969490162,1.4382450552811312,-0.14008827619228245,-1.0228587054425817,0.14483658048926837,-0.8025083410499405,4.011752901252815,2.2716465763795988,3.4171394805890736,0.39259560337501387,0.5003038219140473,-0.4053649182267038,-1.4765043166587404,1.9782122047843376,0.7636623002448963,0.22829128088385117,0.22829128088385117,0.08869434652356714,0.25591244186398043,0.22829128088385117,2.4922302839791723,0.17275463656922826,2.4922302839791723,-0.14008827619228245,0.47350891704813686,0.25591244186398043,1.4382450552811312,2.1146206568398127
3,375
Transport of small molecules
45
155
3.549726
0.000386
P28072,Q13546,Q8WTV0,Q9BUN8,Q8TDW0,Q8N4V1,Q99436,Q9UBX3,Q9UBV2,P20618,P21796,P28288,Q9Y277,Q93050,Q9H2J7,P11166,P12236,P61421,P53985,O15118,Q10713,P30519,P08183,P12235,P51798,P49721,P45880,Q92530,P28074,P35612,P09601,P21281,P28070,Q9C0H2,Q9HD20,Q14997,P30825,P60900,Q9NUT2,P35610,Q9UI12,P27105,Q4KMQ2,Q70HW3,Q13555
Processes and pathways
Reactome Pathways
msigdb_reactome
129,626,6,533,530,11,672,144,678,147,24,653,552,155,546,651,541,287,657,285,414,41,53,54,180,59,62,63,557,308,68,446,205,80,209,212,85,597,495,102,235,479,360,242,505
941,2258,2366,2022,2789,285,1709,1165,1022,1787,1954,784,1788,3112,2096,2027,1714,1113,2461,2619,865,2029,2989,53,2373,2914,68,1027,651,54,541,2544,1064,870,1794,2583,1541,2215,147,446,1857,3082,24,1425,786,1227,1426,479,2795,205,129,557,653,41,2882,85,2739,102,2797,308,3062,3093,2769,1660,2859,3264,1428,826,2276,62,992,686,59,1552,180,2772,657,2045,2168,2326,2327,597,752,287,3298,2742,2222,1604,2382,660,1556,2383,2175,1037,1440,414,2121,1331,626,505,1974,212,1076,2557,1336,360,1747,242,923,3107,11,1339,1823,762,530,6,1005,1619,63,1397,155,1512,1930,672,1686,1625,3203,2136,1626,533,80,3140,546,849,930,209,1253,495,1310,2203,678,144,3290,1841,235,2729,1472,2414,2207,552,2904,741,2018,2694,1586
0.36544472945786843,-0.3160348969490162,-0.3754892338100565,-0.1983298434546702,-0.7094431280794159,1.0945945877969334,-0.05350303097992167,0.22829128088385117,0.31086666228014365,-0.08226034641678645,-0.16915765752368028,0.47350891704813686,-0.08226034641678645,-1.1829292935550804,-0.2276042406016599,-0.1983298434546702,-0.05350303097992167,0.25591244186398043,-0.43533889653030694,-0.5562072945734238,0.41965586752605055,-0.1983298434546702,-0.9594503693142111,2.5792918852390194,-0.3754892338100565,-0.8337145938116572,2.4703624293785205,0.31086666228014365,0.5801743268480191,2.5792918852390194,0.6855048182603979,-0.49557962951464074,0.28343716336325137,0.41965586752605055,-0.08226034641678645,-0.5258453497283577,0.03213471430384632,-0.28645733903368353,1.700034827064007,0.8153801473078209,-0.11112230190969725,-1.0866228857275761,3.356198648789754,0.08869434652356714,0.47350891704813686,0.2005724364337766,0.08869434652356714,0.7636623002448963,-0.7094431280794159,1.4141012478824513,1.8400454612708395,0.6592940398904245,0.5801743268480191,2.857891489435327,-0.8025083410499405,2.2270083787382036,-0.6478655125716591,2.092004590409298,-0.7094431280794159,1.0444625558272569,-1.0546965194844964,-1.1186374013991909,-0.6786074245996516,-0.024850986633067236,-0.771394044942476,-1.6425467075224687,0.08869434652356714,0.44662661518260455,-0.3160348969490162,2.514056875953885,0.33820212925301407,0.5536355300185024,2.5358424878703127,0.03213471430384632,1.5103236781354623,-0.6786074245996516,0.5801743268480191,-0.1983298434546702,-0.2569802644281954,-0.34571237893882045,-0.34571237893882045,0.6330026427578571,0.5003038219140473,1.0945945877969334,-1.9465598176439003,-0.6478655125716591,-0.28645733903368353,0.0036951455715587326,-0.3754892338100565,0.5801743268480191,0.03213471430384632,-0.3754892338100565,-0.2569802644281954,0.31086666228014365,0.08869434652356714,0.8667959860819097,-0.2276042406016599,0.14483658048926837,0.6066297150102449,0.7376880792986121,-0.16915765752368028,1.3656340456729201,0.28343716336325137,-0.49557962951464074,0.14483658048926837,0.9433672737733582,-0.05350303097992167,1.2679658226874506,0.39259560337501387,-1.150739668468142,3.9339465846713644,0.14483658048926837,-0.08226034641678645,0.5003038219140473,0.7116358722612617,4.432259380667763,0.33820212925301407,0.0036951455715587326,2.514056875953885,0.11681693759758847,1.6529390108089894,0.060467414101225296,-0.14008827619228245,0.5801743268480191,-0.024850986633067236,0.0036951455715587326,-1.3778800978198302,-0.2276042406016599,0.0036951455715587326,0.7116358722612617,2.2716465763795988,-1.2152058878452634,0.6855048182603979,0.44662661518260455,0.39259560337501387,1.3898977585599475,0.2005724364337766,0.7636623002448963,0.17275463656922826,-0.2569802644281954,0.5801743268480191,1.7235018312297918,-1.844498937224531,-0.08226034641678645,1.292476019958997,-0.6172178657741221,0.08869434652356714,-0.3754892338100565,-0.2569802644281954,0.6855048182603979,-0.8025083410499405,0.5270123572912739,-0.16915765752368028,-0.5866649642761562,0.03213471430384632
3,375
Nuclear outer membrane endoplasmic reticulum membrane network
77
315
3.540039
0.0004
Q15005,Q9BUN8,Q8TDW0,O15260,Q8N4V1,Q99720,Q70UQ0,Q5BJF2,Q9HCU5,Q14108,P48449,P67812,Q99442,P30519,Q9Y282,Q15392,Q9UBM7,Q96RL7,P09601,Q96G23,P07099,O60725,Q96GC9,O75844,Q8IV08,Q99640,P35610,Q9BRR6,Q9C0D9,Q03518,Q7Z2K6,Q9Y394,P48651,Q9P2W9,Q4ZIN3,Q15629,O43865,Q86XL3,Q14739,Q8N511,Q16850,Q9NZ08,Q9HD20,Q8N5M9,Q8TC12,Q86YN1,Q6NUM9,Q969X5,P38435,P04035,P49069,Q06136,Q9NX47,Q13190,Q6IAN0,Q2TAA5,Q96PC5,P57088,P46977,Q9BT22,Q9H2C2,Q9Y4P3,A1L0T0,P50402,P37268,Q15436,Q92890,Q8N0U8,Q07065,Q96N66,Q9NXE4,O95070,Q96BY7,Q9H2M9,Q9Y678,Q8NF37,Q13555
Localization
GO Cellular component
msigdb_gocc
506,533,530,9,11,12,527,21,547,31,32,34,577,41,49,51,57,58,68,70,76,82,84,88,94,95,102,103,109,111,116,127,141,150,149,154,161,170,174,178,186,204,209,225,226,224,223,232,245,253,272,280,304,296,315,313,335,342,341,365,404,408,391,413,412,436,439,437,434,453,470,461,487,493,517,508,505
2696,391,1157,1475,1019,1708,2617,3255,1949,1221,1162,976,2308,1105,820,1361,9,1164,2987,1222,2907,3367,1844,161,1478,2854,82,1953,3350,710,2967,1954,1848,88,2542,822,2700,1023,3112,1482,982,461,588,2371,1316,1959,1062,983,903,1536,253,3105,2101,2913,2372,2543,76,2422,1169,68,1892,2830,1540,1064,1795,2107,3036,1718,1719,3038,3083,2662,2663,2586,41,2882,1271,988,1325,102,3062,412,245,1599,1034,1963,593,341,1864,32,141,1431,272,621,2798,2044,1432,413,2708,718,2220,1120,2771,793,1967,595,1379,2327,342,1735,1736,1970,2512,952,1738,2709,2920,1383,2282,2862,913,1971,2711,1555,1121,34,687,2974,623,111,914,280,434,1441,955,2121,2286,1498,2630,296,505,2434,31,2554,1560,918,724,174,1190,506,3043,1288,2556,3095,2389,51,436,3210,154,1335,2635,1336,3270,186,313,149,959,21,1676,2234,2867,315,1919,223,1985,1986,3234,1747,2130,1239,527,116,3152,1081,2395,170,962,224,94,3097,2981,1753,437,3245,805,11,178,2845,225,2442,508,1924,573,2349,3153,762,226,1298,2927,1455,1084,530,2719,2846,2560,3283,3086,2870,2720,439,964,1462,1463,232,1464,1007,2604,487,1928,70,84,2526,1573,3313,1758,453,335,58,3170,2562,3222,577,1516,95,12,3335,2244,103,3108,2067,365,1304,533,3003,3357,3026,2813,3055,109,1689,1631,3140,1145,404,493,1934,1148,1518,1632,547,209,1936,3319,1886,2815,1215,1255,675,304,470,3171,1636,204,771,613,1701,2144,2875,150,1582,740,57,3173,678,1775,1841,894,2081,2494,3109,1473,49,1408,127,3031,1258,2415,408,818,938,1946,644,517,1645,1312
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594503693142111,-3.261532807782791,-0.9911098512078583,-0.7094431280794159,-1.0228587054425817,2.0238730257815676,-0.024850986633067236,0.0036951455715587326,-1.2152058878452634,0.25591244186398043,0.8923926409127418,0.7636623002448963,-0.14008827619228245,0.25591244186398043,0.060467414101225296,0.0036951455715587326,0.6855048182603979,1.3898977585599475,-0.14008827619228245,-2.1874571096956763,-0.11112230190969725,-0.7094431280794159,0.22829128088385117,0.2005724364337766,0.5801743268480191,1.0695626309218393,0.7895593798784971,-1.2800184510915182,0.0036951455715587326,1.4382450552811312,0.5003038219140473,0.6330026427578571,-0.024850986633067236,-0.2276042406016599,-0.771394044942476,1.700034827064007,0.03213471430384632,0.5270123572912739,2.5792918852390194,-1.2800184510915182,0.5801743268480191,-0.05350303097992167,-0.08226034641678645,0.41965586752605055,-0.1983298434546702,-0.43533889653030694,-1.150739668468142,0.08869434652356714,2.6441655068947094,0.11681693759758847,1.8631989005372565,-0.9911098512078583,0.2005724364337766,-0.3754892338100565,0.8923926409127418,0.47350891704813686,0.39259560337501387,-0.14008827619228245,0.6066297150102449,0.7376880792986121,0.0036951455715587326,0.17275463656922826
3,375
Alcohol metabolic process
23
82
3.507704
0.000452
P00374,Q8WTV0,Q00796,Q9H2C2,P48449,O15118,Q10713,P37268,P05067,Q14739,P30837,Q15392,Q9UBM7,Q16850,Q9NRA0,O94788,Q8TC12,Q6NUM9,P35610,P04062,Q9BY49,P04035,Q9Y394
Processes and pathways
GO Biological process
msigdb_gobp
131,6,261,404,32,285,414,412,166,174,47,51,57,186,193,75,226,223,102,358,385,253,127
857,285,1164,2987,2575,1953,1954,2764,75,3112,2212,131,1536,253,358,166,746,714,1657,1266,2315,2463,2831,1540,2623,715,2737,47,2955,102,412,1177,1274,32,3307,448,2165,1664,2919,1120,1180,2510,2115,2835,3298,2175,261,2940,1669,414,1038,2890,1672,1916,724,174,1190,1039,2126,51,1335,2635,1980,186,2186,223,839,226,6,3127,2006,2296,1304,1629,385,404,2142,193,551,57,2950,127
0.41965586752605055,1.0945945877969334,0.22829128088385117,-0.9594503693142111,-0.5258453497283577,-0.16915765752368028,-0.16915765752368028,-0.6786074245996516,2.3382725296462423,-1.1829292935550804,-0.28645733903368353,1.8168408195595176,0.03213471430384632,1.2187556408509548,0.9433672737733582,1.5580872461878,0.5003038219140473,0.5270123572912739,-0.024850986633067236,0.17275463656922826,-0.34571237893882045,-0.43533889653030694,-0.74037215539053,0.03213471430384632,-0.5562072945734238,0.5270123572912739,-0.6478655125716591,2.6441655068947094,-0.8964011979097756,2.092004590409298,0.8667959860819097,0.22829128088385117,0.17275463656922826,3.130252972308468,-2.0493327505938783,0.8153801473078209,-0.2569802644281954,-0.024850986633067236,-0.8337145938116572,0.25591244186398043,0.22829128088385117,-0.4654106405661174,-0.2276042406016599,-0.74037215539053,-1.9465598176439003,-0.2569802644281954,1.1940544547326637,-0.8650123589926522,-0.024850986633067236,0.8667959860819097,0.31086666228014365,-0.8025083410499405,-0.024850986633067236,-0.14008827619228245,0.5270123572912739,1.5342340098871912,0.22829128088385117,0.31086666228014365,-0.2276042406016599,2.6009562194312528,0.14483658048926837,-0.5562072945734238,-0.16915765752368028,1.486355749287792,-0.2569802644281954,1.3169237397506999,0.44662661518260455,1.3169237397506999,4.432259380667763,-1.1829292935550804,-0.16915765752368028,-0.3160348969490162,0.17275463656922826,0.0036951455715587326,0.91791615126421,0.8923926409127418,-0.2276042406016599,1.4623297140439213,0.6855048182603979,2.5792918852390194,-0.8650123589926522,1.8631989005372565
3,375
Mitochondrial carrier domain superfamily [IPR023395]
13
23
3.491848
0.00048
P53007,P12236,Q9BQT8,Q86VD7,Q9Y619,Q9H2D1,O43772,Q9UBX3,Q9BSK2,Q70HW3,Q9Y6C9,P12235,Q9HC21
Sequence
InterPro Superfamily
interpro_homologous_superfamily
162,541,490,133,475,81,15,144,18,242,584,54,192
15,1314,1847,865,54,541,162,598,1280,1291,1614,242,133,490,18,81,930,192,772,144,2205,475,584
3.697871107665648,0.14483658048926837,-0.11112230190969725,0.41965586752605055,2.5792918852390194,0.6855048182603979,1.5818838811891258,0.6330026427578571,0.17275463656922826,0.17275463656922826,0.0036951455715587326,1.2679658226874506,1.8168408195595176,0.7636623002448963,3.6780129047155596,2.2716465763795988,0.39259560337501387,1.4623297140439213,0.5003038219140473,1.7235018312297918,-0.2569802644281954,0.7895593798784971,0.6592940398904245
3,375
Mitochondrial substrate/solute carrier [IPR018108]
13
23
3.491848
0.00048
P53007,P12236,Q9BQT8,Q86VD7,Q9Y619,Q9H2D1,O43772,Q9UBX3,Q9BSK2,Q70HW3,Q9Y6C9,P12235,Q9HC21
Sequence
InterPro Repeat
interpro_repeat
162,541,490,133,475,81,15,144,18,242,584,54,192
15,1314,1847,865,54,541,162,598,1280,1291,1614,242,133,490,18,81,930,192,772,144,2205,475,584
3.697871107665648,0.14483658048926837,-0.11112230190969725,0.41965586752605055,2.5792918852390194,0.6855048182603979,1.5818838811891258,0.6330026427578571,0.17275463656922826,0.17275463656922826,0.0036951455715587326,1.2679658226874506,1.8168408195595176,0.7636623002448963,3.6780129047155596,2.2716465763795988,0.39259560337501387,1.4623297140439213,0.5003038219140473,1.7235018312297918,-0.2569802644281954,0.7895593798784971,0.6592940398904245
3,375
SLC25 family of mitochondrial transporters
13
23
3.491848
0.00048
P53007,P12236,Q9BQT8,Q86VD7,Q9Y619,Q9H2D1,O43772,Q9UBX3,Q9BSK2,Q70HW3,Q9Y6C9,P12235,Q9HC21
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
162,541,490,133,475,81,15,144,18,242,584,54,192
15,1314,1847,865,54,541,162,598,1280,1291,1614,242,133,490,18,81,930,192,772,144,2205,475,584
3.697871107665648,0.14483658048926837,-0.11112230190969725,0.41965586752605055,2.5792918852390194,0.6855048182603979,1.5818838811891258,0.6330026427578571,0.17275463656922826,0.17275463656922826,0.0036951455715587326,1.2679658226874506,1.8168408195595176,0.7636623002448963,3.6780129047155596,2.2716465763795988,0.39259560337501387,1.4623297140439213,0.5003038219140473,1.7235018312297918,-0.2569802644281954,0.7895593798784971,0.6592940398904245
3,375
Organic acid transport
20
50
3.478245
0.000505
Q8TDW0,P09455,O43772,P31751,Q9UBX3,P23786,P28288,Q9H2J7,P11166,P53007,P08183,Q6P4A7,P50416,Q7L0J3,Q9Y619,Q9H2D1,P30825,Q9BQT8,O95563,P14174
Processes and pathways
GO Biological process
msigdb_gobp
530,267,15,148,144,20,653,546,651,162,53,568,311,69,475,81,85,490,616,255
1221,2539,2657,1709,15,1314,1416,1847,2542,616,983,2502,2156,2734,867,53,2373,267,651,255,20,653,85,148,988,1430,311,162,657,2168,1280,1038,1288,2556,2557,1747,568,69,530,1760,490,81,546,930,1884,144,2205,2206,2904,475
0.2005724364337766,-0.49557962951464074,-0.5866649642761562,-0.05350303097992167,3.697871107665648,0.14483658048926837,0.08869434652356714,-0.11112230190969725,-0.49557962951464074,0.6066297150102449,0.33820212925301407,-0.4654106405661174,-0.2569802644281954,-0.6478655125716591,0.41965586752605055,2.5792918852390194,-0.3754892338100565,1.1692883875750077,0.5801743268480191,1.2187556408509548,3.457609530408841,0.5801743268480191,2.2270083787382036,1.700034827064007,0.33820212925301407,0.08869434652356714,1.0444625558272569,1.5818838811891258,0.5801743268480191,-0.2569802644281954,0.17275463656922826,0.31086666228014365,0.17275463656922826,-0.49557962951464074,-0.49557962951464074,-0.05350303097992167,0.6592940398904245,2.4484530262047968,0.7116358722612617,-0.05350303097992167,0.7636623002448963,2.2716465763795988,0.6855048182603979,0.39259560337501387,-0.11112230190969725,1.7235018312297918,-0.2569802644281954,-0.2569802644281954,-0.8025083410499405,0.7895593798784971
3,375
transporter
28
57
3.475402
0.00051
O60830,Q96EE3,O15397,Q9UIA9,O43772,O00410,Q9H2V7,Q567V2,Q9Y5L0,Q99595,O14617,P53007,Q9HD45,Q99805,P53985,O43681,Q9NR77,Q9HAV4,Q12769,Q9Y619,Q8TEX9,Q9H2D1,Q9C0E2,P52294,Q92544,Q9UI26,Q6N075,Q15070
Functions
Panther Protein class
panther_protein_class
0,669,265,406,15,518,809,23,818,28,645,162,163,36,657,683,61,455,562,475,605,81,218,719,356,370,361,378
518,1476,645,1360,1105,265,2370,683,15,3356,2150,0,2026,1535,2163,2467,1430,1431,2509,793,719,1966,162,657,876,1734,1383,562,1334,378,23,361,3312,2805,1509,1202,2719,605,356,1398,669,1009,2563,28,36,2195,218,81,809,455,163,61,370,406,2729,818,475
0.7116358722612617,0.060467414101225296,0.5801743268480191,0.11681693759758847,0.25591244186398043,1.1692883875750077,-0.3754892338100565,0.5536355300185024,3.697871107665648,-3.224685614946227,-0.2569802644281954,6.177852396500397,-0.1983298434546702,0.03213471430384632,-0.2569802644281954,-0.43533889653030694,0.08869434652356714,0.08869434652356714,-0.4654106405661174,0.47350891704813686,0.5270123572912739,-0.16915765752368028,1.5818838811891258,0.5801743268480191,0.41965586752605055,-0.05350303097992167,0.11681693759758847,0.6592940398904245,0.14483658048926837,0.91791615126421,3.3968574822924804,0.9433672737733582,-2.083747233101994,-0.7094431280794159,0.060467414101225296,0.22829128088385117,-0.6172178657741221,0.6330026427578571,0.9687467516697891,0.11681693759758847,0.5801743268480191,0.33820212925301407,-0.49557962951464074,3.294970582891578,3.0262046723466742,-0.2569802644281954,1.3413095590408202,2.2716465763795988,0.47350891704813686,0.8153801473078209,1.5818838811891258,2.5358424878703127,0.9433672737733582,0.8923926409127418,-0.6172178657741221,0.47350891704813686,0.7895593798784971
3,375
Organic acid transmembrane transport
16
33
3.398937
0.000676
P11166,P53007,Q9BQT8,Q8TDW0,Q9Y619,Q9H2D1,O43772,P31751,Q9UBX3,P23786,P30825,P08183,P28288,O95563,P50416,Q9H2J7
Processes and pathways
GO Biological process
msigdb_gobp
651,162,490,530,475,81,15,148,144,20,85,53,653,616,311,546
1221,15,1416,1847,2542,616,2734,53,2373,651,20,653,85,148,988,1430,311,162,657,1280,1288,2557,530,1760,490,81,546,930,1884,144,2205,2904,475
0.2005724364337766,3.697871107665648,0.08869434652356714,-0.11112230190969725,-0.49557962951464074,0.6066297150102449,-0.6478655125716591,2.5792918852390194,-0.3754892338100565,0.5801743268480191,3.457609530408841,0.5801743268480191,2.2270083787382036,1.700034827064007,0.33820212925301407,0.08869434652356714,1.0444625558272569,1.5818838811891258,0.5801743268480191,0.17275463656922826,0.17275463656922826,-0.49557962951464074,0.7116358722612617,-0.05350303097992167,0.7636623002448963,2.2716465763795988,0.6855048182603979,0.39259560337501387,-0.11112230190969725,1.7235018312297918,-0.2569802644281954,-0.8025083410499405,0.7895593798784971
3,375
Lipid biosynthetic process
36
146
3.389716
0.0007
Q8WTV0,Q8NCC3,Q9H2C2,P09455,P35790,P48651,Q06136,P48449,Q9NPH0,Q99805,Q9HCL2,Q10713,P37268,Q14739,Q15392,Q8WXW3,Q9UBM7,Q6IAN0,Q16850,Q9H3P7,Q9NRA0,Q96N66,Q96G23,P49748,O94788,Q16739,Q9BYI3,Q86YN1,P35610,Q9UHD1,Q9C0D9,P04062,Q8NBX0,Q9BY49,P04035,P14174
Processes and pathways
GO Biological process
msigdb_gobp
6,7,404,267,13,141,280,32,35,36,172,414,412,174,51,318,57,315,186,60,193,453,70,448,75,78,86,224,102,369,109,358,120,385,253,255
1103,896,1220,1160,2617,1648,1162,1361,1163,1164,2987,782,1953,1954,2764,75,3112,1316,983,2501,2212,903,1536,253,358,2156,2461,3218,267,1657,1225,255,2315,2831,3333,1540,3257,715,1718,1898,2737,2377,1800,653,1176,988,102,13,412,1034,1177,32,141,875,448,1180,2510,1969,2552,2940,1669,280,414,797,1038,2890,1916,918,724,174,1190,2126,2865,51,1445,1335,2635,78,1980,186,3233,959,1503,315,2130,3152,2716,224,1395,120,7,1996,508,6,2959,1571,1619,318,2898,2870,2720,1462,2005,926,70,453,3127,2809,2562,1575,1687,3052,36,2244,2564,3373,3026,2298,2299,385,86,109,404,60,1148,3337,172,35,2142,193,3079,1215,1255,675,551,470,1636,613,2144,740,57,854,369,933,1841,2082
0.25591244186398043,0.39259560337501387,0.2005724364337766,0.22829128088385117,-0.5562072945734238,-0.024850986633067236,0.22829128088385117,0.11681693759758847,0.22829128088385117,0.22829128088385117,-0.9594503693142111,0.47350891704813686,-0.16915765752368028,-0.16915765752368028,-0.6786074245996516,2.3382725296462423,-1.1829292935550804,0.14483658048926837,0.33820212925301407,-0.4654106405661174,-0.28645733903368353,0.39259560337501387,0.03213471430384632,1.2187556408509548,0.9433672737733582,-0.2569802644281954,-0.43533889653030694,-1.4435454454021128,1.1692883875750077,-0.024850986633067236,0.2005724364337766,1.2187556408509548,-0.34571237893882045,-0.74037215539053,-2.502718876001027,0.03213471430384632,-1.609172964600143,0.5270123572912739,-0.05350303097992167,-0.14008827619228245,-0.6478655125716591,-0.3754892338100565,-0.08226034641678645,0.5801743268480191,0.22829128088385117,0.33820212925301407,2.092004590409298,3.7572720143403053,0.8667959860819097,0.31086666228014365,0.22829128088385117,3.130252972308468,1.7235018312297918,0.41965586752605055,0.8153801473078209,0.22829128088385117,-0.4654106405661174,-0.16915765752368028,-0.49557962951464074,-0.8650123589926522,-0.024850986633067236,1.1195590959099642,0.8667959860819097,0.47350891704813686,0.31086666228014365,-0.8025083410499405,-0.14008827619228245,0.39259560337501387,0.5270123572912739,1.5342340098871912,0.22829128088385117,-0.2276042406016599,-0.771394044942476,2.6009562194312528,0.08869434652356714,0.14483658048926837,-0.5562072945734238,2.2716465763795988,-0.16915765752368028,1.486355749287792,-1.4765043166587404,0.36544472945786843,0.060467414101225296,1.0444625558272569,-0.2276042406016599,-1.2475690670035406,-0.6172178657741221,1.3169237397506999,0.11681693759758847,1.9093538048745637,4.337756409373861,-0.16915765752368028,0.7376880792986121,4.432259380667763,-0.8964011979097756,0.03213471430384632,0.0036951455715587326,1.0444625558272569,-0.8025083410499405,-0.771394044942476,-0.6172178657741221,0.08869434652356714,-0.16915765752368028,0.39259560337501387,2.426501785073673,0.8153801473078209,-1.1829292935550804,-0.7094431280794159,-0.49557962951464074,0.03213471430384632,-0.024850986633067236,-1.0228587054425817,3.0262046723466742,-0.28645733903368353,-0.49557962951464074,-10.357023878767876,-0.9911098512078583,-0.3160348969490162,-0.3160348969490162,0.91791615126421,2.2270083787382036,2.0238730257815676,0.8923926409127418,2.5358424878703127,0.25591244186398043,-2.502718876001027,1.5580872461878,3.0887372059217104,-0.2276042406016599,1.4623297140439213,-1.0546965194844964,0.22829128088385117,0.2005724364337766,0.5801743268480191,0.6855048182603979,0.7895593798784971,0.0036951455715587326,0.6330026427578571,-0.2276042406016599,0.5270123572912739,2.5792918852390194,0.44662661518260455,0.9433672737733582,0.39259560337501387,-0.08226034641678645,-0.1983298434546702
3,375
Potential drug targets
122
499
3.298018
0.000974
P50570,Q13126,Q02252,O15047,O43772,P49366,Q9NX62,Q14108,P48449,P08243,P00403,Q96GW9,P42892,Q15392,Q9UBM7,P50897,Q6P4A7,Q96RL7,O94761,Q9H061,O60343,O96028,P09601,Q12769,P07099,Q9H2D1,Q9HD26,O75844,Q00535,Q00325,Q8IV08,O95630,P13073,Q96BN8,Q9C0D9,Q03518,Q9NVH6,Q7Z4W1,P49257,P07384,P38935,Q8NCH0,Q13546,Q86VD7,Q2M389,O95677,Q92621,Q96J02,P48651,Q9NVV0,P31751,Q9UJV9,O43933,P28288,P08236,Q6P4Q7,P11166,P53007,P53985,P55263,Q6UWE0,Q14739,Q9UHD2,Q8N511,P51798,P26640,Q9HC21,P06865,Q9NRA0,Q4J6C6,O14773,P10619,P28070,P16278,P78330,Q8TC12,P53701,Q70HW3,P14174,Q00796,P04066,Q06136,Q99575,P11117,O15118,Q9HC07,Q96RR1,Q96AY3,Q8TD19,Q6P3W7,Q2TAA5,Q96PC5,P46977,O14646,P49589,Q8TD30,Q9BT22,Q4KMQ2,P04062,Q9Y223,Q9NSE4,P78527,Q9H2C2,Q16740,Q10713,P37268,P06280,O60566,Q93008,Q96N66,P49748,P17812,Q9Y619,Q9NXE4,Q9BQT8,P54802,O15164,Q06210,Q08209,Q8NI60,Q6ZXV5,Q13555
Functions
Protein Atlas Protein class
protein_atlas_protein_class
503,1,2,499,15,520,551,31,32,539,538,575,50,51,57,55,568,58,554,64,553,65,68,562,76,81,610,88,599,598,94,589,591,108,109,111,641,117,621,123,619,126,626,133,132,136,668,670,141,675,148,679,145,653,650,159,651,162,657,658,169,174,704,178,180,685,192,684,193,191,188,196,205,207,214,226,237,242,255,261,266,280,291,286,285,302,301,299,298,297,313,335,341,350,352,364,365,360,358,390,388,375,404,417,414,412,432,431,452,453,448,444,475,470,490,480,476,482,483,509,507,505
1103,2148,1475,1220,1019,1413,975,3187,1948,350,1221,2539,188,779,819,499,285,1361,476,1163,1164,2987,1785,1107,2459,1530,1166,3367,2498,15,145,745,1532,2149,553,1478,2092,431,2854,2731,2698,1953,2576,1022,1365,861,1480,1787,1954,2791,1261,1367,2026,1847,1848,2311,88,822,1263,554,3112,2579,982,1956,2371,1849,1369,1316,1418,589,136,1485,65,2421,1536,538,2502,2312,3013,358,266,1265,1318,3345,2503,3105,2733,2313,2102,1790,432,985,2158,684,76,2989,123,1420,3218,1486,867,2969,650,824,539,1168,2374,1063,714,68,2375,2879,196,3237,286,651,2270,2032,1028,2581,3327,1657,2033,1854,1895,3189,591,986,255,1791,2856,207,1540,2971,1794,444,2546,2316,905,3116,747,2584,1797,1490,1115,3219,1898,1719,2737,1174,1226,2507,1859,1543,1321,2377,1721,748,2378,1270,685,749,205,653,2832,825,2663,1723,1900,148,2833,3317,1725,1323,3315,2955,1598,2163,3093,1659,2859,2884,2624,1802,2706,2467,412,2860,3264,2707,619,1599,826,2040,1429,1600,2275,991,50,2380,1493,341,1327,3018,32,2111,141,621,520,3308,2043,352,1965,1229,448,1432,2918,1230,2472,1277,503,1662,55,2323,2801,1663,1664,2220,1120,1278,2167,180,1730,1966,829,162,1179,1435,2510,2772,237,657,1968,2325,1069,1732,480,3063,1806,2327,3041,658,951,1666,1734,2115,1737,1970,2511,2835,2920,1383,3298,3136,2170,1555,214,375,598,599,1037,261,1669,2,2974,1280,1497,111,688,915,1385,877,280,482,1608,483,1187,1441,1073,414,562,2121,2180,1281,797,1,1442,1332,2890,626,505,2434,31,1869,1126,1501,174,1610,2125,1870,799,2438,2126,51,1335,2635,1336,417,1980,1565,132,313,1981,2186,3022,3233,191,360,1503,1130,758,3137,1745,1449,2867,2129,1614,2637,1747,297,568,159,1987,3312,169,507,242,2750,1293,1195,2344,117,1044,133,2716,94,1753,1297,1509,805,178,2559,2442,2895,1616,126,2398,925,1202,509,1824,226,1298,2927,298,364,1003,2560,1571,1619,1086,668,2720,2002,452,964,1464,1007,299,108,2242,841,1512,1572,575,1247,3306,670,1685,453,335,842,58,1301,301,3222,1515,1930,2006,1516,2563,291,2136,2296,2447,1626,1761,490,365,2402,1883,1011,1212,1578,109,1689,64,2607,2533,3140,404,81,2902,1147,849,736,930,3102,302,192,1768,1520,610,2013,1696,1937,1836,2301,193,1403,2815,738,388,1580,641,675,1309,1310,813,2818,551,470,3171,2567,1636,1098,2760,57,3173,2080,1840,1774,3080,1775,704,2251,2205,679,3109,1311,2692,1638,1356,1357,390,1843,1407,1408,2851,3032,2730,2018,742,2537,856,1526,973,2256,475
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3,375
Endoplasmic reticulum
113
494
3.284987
0.00102
Q15005,Q9BUN8,Q8TDW0,O15260,Q8N4V1,Q99720,Q70UQ0,Q02818,Q5BJF2,Q9HCU5,Q14108,P48449,P67812,Q13641,Q99442,Q8IXB1,P30519,Q8NHH9,Q9H6V9,Q9Y282,Q15392,Q9UBM7,Q96RL7,Q92530,P09601,Q7L0J3,Q96G23,P07099,O60725,Q96GC9,O75844,Q9UQB8,Q8IV08,Q99640,P80303,O75503,P35610,Q9BRR6,Q9C0D9,Q03518,Q7Z2K6,Q8TCD1,Q9Y394,P48651,Q9P2W9,Q4ZIN3,Q15629,P27635,O43865,Q86XL3,P42858,P05067,Q14739,Q8N511,Q96LJ7,Q12768,Q16850,Q9NRA0,Q9NZ08,O15173,P10619,Q9HD20,Q14257,Q8N5M9,Q9BRK5,Q8TC12,Q86YN1,Q6NUM9,Q969X5,P38435,P04035,Q15631,P49069,Q06136,O15118,Q9NX47,Q96AY3,Q13190,Q6IAN0,Q2TAA5,Q96PC5,P62266,O95456,P57088,O94832,P46977,Q9UHD1,Q9BT22,P04062,O15258,P61960,Q9H2C2,Q9Y4P3,P52789,A1L0T0,Q8IZP0,P50402,P37268,Q15436,Q92890,Q8N0U8,Q07065,Q96N66,Q9NXE4,O95070,Q96BY7,Q9H2M9,Q9Y296,P27105,Q9Y678,Q6ZXV5,Q8NF37,Q13555
Localization
GO Cellular component
msigdb_gocc
506,533,530,9,11,12,527,523,21,547,31,32,34,543,577,571,41,573,48,49,51,57,58,63,68,69,70,76,82,84,88,90,94,95,97,98,102,103,109,111,116,118,127,141,150,149,154,158,161,170,167,166,174,178,183,181,186,193,204,195,196,209,215,225,228,226,224,223,232,245,253,262,272,280,285,304,299,296,315,313,335,329,325,342,339,341,369,365,358,357,373,404,408,396,391,423,413,412,436,439,437,434,453,470,461,487,493,497,479,517,507,508,505
2696,391,3276,1157,1475,1019,1708,975,2617,3255,1949,3269,1221,1162,976,2308,820,285,1361,195,357,9,1164,2987,3338,2459,1651,1222,1362,2907,3367,2790,683,1844,161,1478,1415,2854,82,1953,1845,1786,3350,710,2967,1954,98,2152,863,1848,88,2542,822,1263,339,2700,1023,3112,1482,982,461,588,2371,2154,325,1316,1959,1062,983,3199,903,1715,2421,1536,253,358,3105,2733,2101,2913,2461,166,2157,2372,76,2989,2735,2422,1169,68,2660,1892,196,1893,3279,3175,2159,3263,1423,2830,1792,1540,1064,870,3257,1795,2765,2107,3036,906,3082,1718,1898,1719,2507,617,2794,3092,1491,3038,479,1799,158,946,3083,2662,1800,2379,2663,2664,2858,2586,41,2796,1176,2882,1271,988,3061,1598,1325,102,3062,1801,654,412,245,1599,2885,1034,167,593,559,1275,1376,341,1864,32,141,620,1431,272,2042,621,2798,2044,413,2886,791,2708,718,2220,1120,2771,793,1328,396,1967,595,1379,2327,3041,3358,3228,342,1735,1736,911,1970,2511,2512,952,1738,2281,2709,2920,1383,2282,3298,2862,373,2863,1911,329,1971,1184,2381,1234,2711,1555,2668,1121,34,97,2669,1607,687,3324,2383,2671,1330,1741,2974,523,661,623,111,914,280,954,434,1441,955,181,2121,1609,2286,1498,2630,2479,296,2051,2746,2890,505,543,2434,31,1868,2554,215,1560,918,724,3265,2748,174,1190,1334,506,3043,1288,2556,3248,3095,2714,1563,2389,51,1502,436,3210,154,262,2288,1335,2635,1336,2185,3270,186,313,1981,149,959,21,1676,2234,2867,835,315,1919,223,1985,1986,3234,1747,3312,2130,1337,1239,507,527,69,116,2844,3152,1081,2395,170,962,224,1082,838,94,2981,571,1753,1877,423,437,3245,1199,805,11,178,2845,225,2442,1616,1395,2944,508,1924,573,2349,3153,762,226,118,1298,2927,1455,530,2063,1925,2719,1617,2846,2560,3283,63,2446,3086,2870,2720,3002,697,439,964,2602,1462,1463,232,1464,1621,1007,2604,299,487,1928,70,84,2526,1573,3313,1758,183,453,335,58,3170,2562,3222,576,577,2006,1516,95,12,3335,2136,2244,228,103,3108,2067,2297,365,1931,1210,1304,533,3003,3357,3026,2813,3055,109,1689,1631,2607,3140,1145,2785,404,2964,493,1934,1147,1148,2725,2490,1518,1692,48,1632,547,209,1936,3319,1886,1771,193,2815,1215,1255,1580,675,813,304,470,3171,3005,1636,204,771,613,1701,2144,2875,1098,815,150,1582,740,57,3173,2614,678,1839,1775,1016,369,1841,894,2081,2494,3109,2819,1311,3195,1583,1473,90,2966,49,497,3215,1408,127,3031,1258,1101,2415,3032,408,938,1946,644,517,1645,1312,743
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3,375
Armadillo-type fold [IPR016024]
67
166
3.22711
0.00125
Q86VP6,P78527,Q86XI2,Q15051,Q5SRE5,O15397,Q9UIA9,Q7Z5K2,Q13395,O00410,Q9BPX3,Q9Y6E2,Q9HAU5,Q9UBB4,P55010,Q8IZT6,O43592,Q9Y5L0,O14617,O75533,P42858,P52292,Q96JJ3,P50851,Q9BTW9,Q6P3W7,P30153,Q8N201,Q8WVM7,Q96QK1,Q92616,Q96T76,Q6NXE6,Q9UBB6,Q93008,Q16537,Q9HAV4,Q6SZW1,Q9Y263,O75155,O94915,Q8TEX9,Q5VW36,P42695,Q14997,Q69YN4,Q5VYK3,Q14999,Q9C0E2,O75691,Q6PJG6,Q7Z3U7,P52294,Q9UI26,Q9UI12,Q9UH62,Q9H583,O43432,Q6KC79,O00203,O94822,Q7Z4Q2,O60287,P55060,Q15021,Q9Y678,Q86Y56
Sequence
InterPro Superfamily
interpro_homologous_superfamily
923,375,134,920,758,265,406,401,275,518,807,682,810,677,151,25,392,818,645,783,167,793,699,791,701,297,789,316,317,842,438,320,692,853,452,689,455,200,338,73,74,605,208,83,212,345,835,216,218,711,884,465,719,370,235,893,765,478,630,858,114,243,860,876,628,517,761
940,858,518,1220,1476,2572,645,1360,1105,1106,265,478,392,1590,860,3356,1479,2150,2698,1845,1786,2151,73,1534,783,711,114,74,2096,1535,1714,2269,2506,789,1175,1903,1034,83,167,791,793,719,1328,1967,151,876,2382,2174,375,1037,2119,2049,1913,1073,1282,1331,275,2124,1501,2893,1975,1334,212,216,628,920,1502,689,1613,1873,1042,1504,758,1448,2391,208,835,3366,345,1079,630,692,297,884,200,1239,2558,2343,1240,465,2058,243,401,1044,1680,923,134,761,2060,25,316,3245,2348,1396,605,1085,317,2445,1049,1342,438,1755,1398,452,699,1009,842,320,1686,1687,807,1303,701,2449,2068,1010,2359,218,3057,1467,1305,765,810,455,2407,1835,969,931,2200,2453,1887,1151,2651,2611,677,853,1582,3205,893,1471,235,370,406,1099,2692,1017,338,2905,1780,1359,1410,1525,818,1411,517,682
0.36544472945786843,0.41965586752605055,0.7116358722612617,0.2005724364337766,0.060467414101225296,-0.5258453497283577,0.5801743268480191,0.11681693759758847,0.25591244186398043,0.25591244186398043,1.1692883875750077,0.7636623002448963,0.8923926409127418,0.0036951455715587326,0.41965586752605055,-3.224685614946227,0.060467414101225296,-0.2569802644281954,-0.6172178657741221,-0.11112230190969725,-0.08226034641678645,-0.2569802644281954,2.360394087286694,0.03213471430384632,0.47350891704813686,0.5270123572912739,1.9782122047843376,2.360394087286694,-0.2276042406016599,0.03213471430384632,-0.05350303097992167,-0.3160348969490162,-0.4654106405661174,0.47350891704813686,0.22829128088385117,-0.14008827619228245,0.31086666228014365,2.249349781196953,1.5580872461878,0.47350891704813686,0.47350891704813686,0.5270123572912739,0.14483658048926837,-0.16915765752368028,1.676514037712598,0.41965586752605055,-0.3754892338100565,-0.2569802644281954,0.91791615126421,0.31086666228014365,-0.2276042406016599,-0.1983298434546702,-0.14008827619228245,0.28343716336325137,0.17275463656922826,0.14483658048926837,1.144456813443884,-0.2276042406016599,0.060467414101225296,-0.8025083410499405,-0.16915765752368028,0.14483658048926837,1.3656340456729201,1.3413095590408202,0.6066297150102449,0.39259560337501387,0.060467414101225296,0.5536355300185024,0.0036951455715587326,-0.11112230190969725,0.31086666228014365,0.060467414101225296,0.5003038219140473,0.08869434652356714,-0.3754892338100565,1.3898977585599475,0.44662661518260455,-4.051094702330439,0.9940553151106681,0.28343716336325137,0.6066297150102449,0.5536355300185024,1.0695626309218393,0.41965586752605055,1.4382450552811312,0.2005724364337766,-0.49557962951464074,-0.34571237893882045,0.2005724364337766,0.7895593798784971,-0.1983298434546702,1.2679658226874506,0.8923926409127418,0.31086666228014365,-0.024850986633067236,0.39259560337501387,1.8168408195595176,0.5003038219140473,-0.1983298434546702,3.335821452262717,1.0444625558272569,-1.5426726974742175,-0.34571237893882045,0.11681693759758847,0.6330026427578571,0.28343716336325137,1.0444625558272569,-0.4053649182267038,0.31086666228014365,0.14483658048926837,0.8411254163810149,-0.05350303097992167,0.11681693759758847,0.8153801473078209,0.5536355300185024,0.33820212925301407,0.44662661518260455,1.0444625558272569,-0.024850986633067236,-0.024850986633067236,0.47350891704813686,0.17275463656922826,0.5536355300185024,-0.4053649182267038,-0.1983298434546702,0.33820212925301407,-0.34571237893882045,1.3413095590408202,-1.0228587054425817,0.08869434652356714,0.17275463656922826,0.5003038219140473,0.47350891704813686,0.8153801473078209,-0.3754892338100565,-0.08226034641678645,0.36544472945786843,0.39259560337501387,-0.2569802644281954,-0.4053649182267038,-0.11112230190969725,0.25591244186398043,-0.5562072945734238,-0.5258453497283577,0.5801743268480191,0.44662661518260455,0.03213471430384632,-1.3778800978198302,0.41965586752605055,0.08869434652356714,1.292476019958997,0.9433672737733582,0.8923926409127418,0.28343716336325137,-0.5866649642761562,0.33820212925301407,1.0192936815049485,-0.8025083410499405,-0.05350303097992167,0.14483658048926837,0.11681693759758847,0.060467414101225296,0.47350891704813686,0.11681693759758847,0.7376880792986121,0.5801743268480191
3,375
Endocytosis
28
127
3.20807
0.001336
P17931,Q08380,Q8WTV0,O15260,P20645,Q7Z3T8,Q5VW38,Q14108,O15118,Q6UWE0,Q13464,P05067,Q6P3W7,Q9UKG1,P50897,O15126,P46934,Q13432,O60784,Q5KU26,P42566,Q96T51,Q9UI12,Q4KMQ2,Q08209,Q15276,Q96ED9,Q8N3F8
Processes and pathways
GO Biological process
msigdb_gobp
256,376,6,9,137,143,19,31,285,169,42,166,297,184,55,443,447,331,460,344,351,489,235,360,483,119,121,124
2696,1158,2306,1475,1220,1708,977,285,443,9,1590,1952,460,1534,980,2096,1714,1113,166,2734,2953,2914,1320,3227,869,2464,1424,256,1795,1961,2990,137,1799,2662,2379,2796,1117,1430,351,447,503,55,2427,2801,2771,2772,1494,1970,2280,3136,1603,2223,2381,2330,1555,2382,687,599,1037,2283,915,2744,483,376,1557,331,42,2631,1673,31,1817,2334,918,2052,2678,1039,2775,119,1563,1979,360,2234,344,566,19,2998,297,169,143,2396,124,2397,2239,2683,6,2001,1512,2982,121,489,1516,1139,2810,2947,2010,2785,1467,703,1837,851,814,2303,1353,740,1471,235,1637,184,3301,2494,1100,1778,2692,1405,2537,2457,2695
-0.6172178657741221,0.22829128088385117,-0.34571237893882045,0.060467414101225296,0.2005724364337766,-0.05350303097992167,0.33820212925301407,1.0945945877969334,0.8153801473078209,4.069826366870343,0.0036951455715587326,-0.16915765752368028,0.7895593798784971,0.03213471430384632,0.33820212925301407,-0.2276042406016599,-0.05350303097992167,0.25591244186398043,1.5580872461878,-0.6478655125716591,-0.8964011979097756,-0.8337145938116572,0.14483658048926837,-1.4765043166587404,0.41965586752605055,-0.43533889653030694,0.08869434652356714,1.2187556408509548,-0.08226034641678645,-0.16915765752368028,-0.9594503693142111,1.7935845599756126,-0.08226034641678645,-0.5866649642761562,-0.3754892338100565,-0.7094431280794159,0.25591244186398043,0.08869434652356714,0.9687467516697891,0.8153801473078209,0.7376880792986121,2.5792918852390194,-0.4053649182267038,-0.7094431280794159,-0.6786074245996516,-0.6786074245996516,0.060467414101225296,-0.16915765752368028,-0.3160348969490162,-1.2152058878452634,0.0036951455715587326,-0.28645733903368353,-0.3754892338100565,-0.34571237893882045,0.03213471430384632,-0.3754892338100565,0.5536355300185024,0.6330026427578571,0.31086666228014365,-0.3160348969490162,0.39259560337501387,-0.6478655125716591,0.7636623002448963,0.91791615126421,0.03213471430384632,1.0192936815049485,2.857891489435327,-0.5562072945734238,-0.024850986633067236,3.1509596999717213,-0.08226034641678645,-0.34571237893882045,0.39259560337501387,-0.1983298434546702,-0.5866649642761562,0.31086666228014365,-0.6786074245996516,1.9553087432535796,0.03213471430384632,-0.16915765752368028,0.9433672737733582,-0.28645733903368353,0.9940553151106681,0.6592940398904245,3.6382087146586084,-0.9594503693142111,1.0695626309218393,1.5580872461878,1.7235018312297918,-0.3754892338100565,1.8863015470497642,-0.3754892338100565,-0.28645733903368353,-0.5866649642761562,4.432259380667763,-0.16915765752368028,0.060467414101225296,-0.9278806773204062,1.9093538048745637,0.7636623002448963,0.060467414101225296,0.25591244186398043,-0.7094431280794159,-0.8650123589926522,-0.16915765752368028,-0.6786074245996516,0.08869434652356714,0.5536355300185024,-0.08226034641678645,0.44662661518260455,0.47350891704813686,-0.3160348969490162,0.14483658048926837,0.5270123572912739,0.08869434652356714,1.292476019958997,0.0036951455715587326,1.5103236781354623,-1.9465598176439003,-0.43533889653030694,0.28343716336325137,-0.05350303097992167,-0.5866649642761562,0.11681693759758847,-0.4654106405661174,-0.4053649182267038,-0.5866649642761562
3,375
Armadillo-like helical [IPR011989]
48
117
3.197448
0.001386
Q86VP6,P78527,Q86XI2,O15397,Q9UIA9,Q7Z5K2,O00410,Q9BPX3,Q9UBB4,O43592,Q8IZT6,Q9Y5L0,O14617,O75533,P42858,P52292,Q96JJ3,P50851,Q9BTW9,Q6P3W7,P30153,Q92616,Q96T76,Q6NXE6,Q16537,Q9HAV4,Q6SZW1,Q9Y263,O75155,Q8TEX9,P42695,Q14997,Q5VYK3,Q9C0E2,Q6PJG6,P52294,Q9UI26,Q9UI12,Q9UH62,Q9H583,Q6KC79,O00203,O94822,Q7Z4Q2,Q9Y678,P55060,Q15021,Q86Y56
Sequence
InterPro Superfamily
interpro_homologous_superfamily
923,375,134,265,406,401,518,807,677,392,25,818,645,783,167,793,699,791,701,297,789,438,320,692,689,455,200,338,73,605,83,212,835,218,884,719,370,235,893,765,630,858,114,243,517,876,628,761
940,858,518,1476,2572,645,1360,1105,1106,265,392,1590,3356,1479,2150,2698,1845,1786,2151,73,1534,783,114,2096,1535,1714,2506,789,1175,1903,1034,83,167,791,793,719,1328,1967,876,2382,375,1073,1331,2124,1501,2893,1975,1334,212,628,1502,689,1613,1504,2391,835,630,692,297,884,200,1240,2058,243,401,1680,923,134,761,2060,25,3245,1396,605,2445,1342,438,1755,1398,699,1009,320,1686,1687,807,1303,701,2449,2068,2359,218,2784,1467,765,455,1835,969,931,2453,1151,2651,2611,677,1582,893,235,370,406,1099,2692,338,2905,1359,1410,818,1411,517
0.36544472945786843,0.41965586752605055,0.7116358722612617,0.060467414101225296,-0.5258453497283577,0.5801743268480191,0.11681693759758847,0.25591244186398043,0.25591244186398043,1.1692883875750077,0.8923926409127418,0.0036951455715587326,-3.224685614946227,0.060467414101225296,-0.2569802644281954,-0.6172178657741221,-0.11112230190969725,-0.08226034641678645,-0.2569802644281954,2.360394087286694,0.03213471430384632,0.47350891704813686,1.9782122047843376,-0.2276042406016599,0.03213471430384632,-0.05350303097992167,-0.4654106405661174,0.47350891704813686,0.22829128088385117,-0.14008827619228245,0.31086666228014365,2.249349781196953,1.5580872461878,0.47350891704813686,0.47350891704813686,0.5270123572912739,0.14483658048926837,-0.16915765752368028,0.41965586752605055,-0.3754892338100565,0.91791615126421,0.28343716336325137,0.14483658048926837,-0.2276042406016599,0.060467414101225296,-0.8025083410499405,-0.16915765752368028,0.14483658048926837,1.3656340456729201,0.6066297150102449,0.060467414101225296,0.5536355300185024,0.0036951455715587326,0.060467414101225296,-0.3754892338100565,0.44662661518260455,0.6066297150102449,0.5536355300185024,1.0695626309218393,0.41965586752605055,1.4382450552811312,0.2005724364337766,-0.1983298434546702,1.2679658226874506,0.8923926409127418,-0.024850986633067236,0.39259560337501387,1.8168408195595176,0.5003038219140473,-0.1983298434546702,3.335821452262717,-1.5426726974742175,0.11681693759758847,0.6330026427578571,-0.4053649182267038,0.14483658048926837,0.8411254163810149,-0.05350303097992167,0.11681693759758847,0.5536355300185024,0.33820212925301407,1.0444625558272569,-0.024850986633067236,-0.024850986633067236,0.47350891704813686,0.17275463656922826,0.5536355300185024,-0.4053649182267038,-0.1983298434546702,-0.34571237893882045,1.3413095590408202,-0.6786074245996516,0.08869434652356714,0.5003038219140473,0.8153801473078209,-0.08226034641678645,0.36544472945786843,0.39259560337501387,-0.4053649182267038,0.25591244186398043,-0.5562072945734238,-0.5258453497283577,0.5801743268480191,0.03213471430384632,0.41965586752605055,1.292476019958997,0.9433672737733582,0.8923926409127418,0.28343716336325137,-0.5866649642761562,1.0192936815049485,-0.8025083410499405,0.14483658048926837,0.11681693759758847,0.47350891704813686,0.11681693759758847,0.7376880792986121
3,375
Transferase
121
383
3.188572
0.00143
Q13126,O15047,Q8NCC3,Q7Z7E8,Q9Y3D8,P35790,Q8IXJ6,Q68CQ7,P23786,P49366,Q13464,Q96SB4,P11274,O96028,Q96G23,Q14012,Q15047,Q99873,Q16739,O60725,Q9H871,Q00535,P12277,Q99640,P31153,P43490,O43813,P35610,Q9BRR6,Q96EP0,Q9C0D9,O94822,Q9Y673,Q8NCH0,Q13546,Q96J02,P48651,P31751,Q7Z6K3,Q16836,P49841,Q9BV86,P49427,Q9HCL2,Q9HA64,P55263,Q6UWE0,Q9UHD2,Q9NRA0,Q04446,Q5VTR2,Q9NR09,Q9UBF8,Q9Y4X5,Q5TAX3,P53611,Q13418,O75116,O95071,Q9H993,Q9UNQ2,P49356,P27708,P30876,Q07864,Q16512,P21127,Q00534,Q13395,Q16762,P49840,Q9UII4,Q7LGA3,Q06203,O14744,O14802,O60678,P09884,P26358,Q9NX47,Q8TD19,Q9C0C9,P50416,Q2TAA5,Q9H4A3,Q9Y5P6,Q99707,Q8IZ69,O14936,P04183,P28340,P48729,Q15386,P46977,Q8TD30,Q9BT22,Q8N1G2,P04062,Q9Y223,P78527,P78417,O00411,Q9UBP6,Q14527,P52789,P37268,P04818,Q9Y314,O60566,O43252,O14929,Q9BWD1,Q96N66,P46934,Q9NRG0,O15164,Q06210,Q8NI60,Q6ZXV5,Q8NF37,Q13555
Functions
Protein Atlas Molecular function
protein_atlas_molecular_function
1,499,7,528,535,13,529,17,20,520,42,576,556,65,70,564,601,606,78,82,609,599,590,95,592,594,101,102,103,635,109,114,644,126,626,670,141,148,665,663,157,160,656,172,171,658,169,704,193,688,690,737,740,742,726,213,723,709,220,767,249,751,749,750,753,756,268,274,275,800,273,295,289,796,778,779,782,785,787,304,298,847,311,313,849,856,336,334,819,327,825,827,343,341,364,365,363,358,390,375,374,372,405,398,396,412,411,442,431,430,429,454,453,447,469,476,482,509,507,508,505
1103,3288,372,1220,1528,1948,1162,778,1058,779,976,429,819,977,499,476,1163,1164,2987,1785,1107,3133,1651,2906,3034,430,1166,1531,1223,2498,101,431,2854,782,82,1953,709,2460,2910,1366,1367,114,2700,220,1368,2701,1713,3012,1418,1485,1370,2501,65,2936,2265,2502,2312,3013,358,2503,327,2266,411,2372,985,1486,824,1168,2580,1853,785,2879,2032,2581,1422,556,1225,2855,590,3114,986,2315,1423,1424,2623,870,1794,1371,905,2584,1029,1489,268,1173,907,2736,1542,908,1898,2317,20,2738,2377,1373,1721,787,2766,1799,749,1800,825,2379,2663,2110,1596,1032,750,592,148,1272,1724,2704,3040,1598,102,13,1801,2706,412,2860,1429,1600,1904,2275,1034,1177,594,2587,447,1493,341,141,827,875,3160,751,520,656,949,1432,273,157,1068,311,1662,2219,1664,1730,3321,396,1179,1180,213,1968,3063,1806,3041,658,911,1737,2169,2667,3121,1810,3230,374,375,2994,274,599,2940,1439,1741,1497,688,915,1385,796,482,753,1187,1441,955,2285,1498,2180,1281,1,1038,1442,2745,2889,1814,275,723,42,2774,626,505,1672,564,1444,398,1501,1870,601,1390,2438,2126,1041,343,2232,2055,756,2127,2440,78,800,1446,663,1565,313,2186,3022,1503,1744,2057,1448,726,690,2867,1983,17,1678,169,2130,3299,507,1567,2750,1195,1749,289,1131,1992,2844,3138,665,1044,528,3023,2394,1133,2059,1045,962,2716,1922,529,1570,334,363,1822,1616,7,126,508,925,3123,509,1298,2927,298,364,963,2779,2870,3139,2293,964,1344,2005,926,635,1572,3155,70,1247,670,928,1685,453,1624,576,1515,1687,95,336,3335,606,2244,2447,1688,103,365,2564,1347,160,3026,1517,454,1211,3027,1578,847,109,1630,1252,2607,1350,1147,849,967,609,767,1633,1307,171,3365,172,1696,1836,737,2301,193,469,1055,1254,3079,1255,1309,304,3005,2567,3295,740,405,1773,1774,704,2251,295,2413,2206,2304,1842,2081,1099,2082,1311,249,1356,390,1585,442,535,1410,2730,742,856,2256,644,3104
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3,375
Amide binding
16
109
3.179271
0.001476
Q02252,O14773,Q9UIQ6,O43813,Q8WTV0,Q9UM22,P35610,P00374,Q9NQX7,Q03518,P42892,Q15392,P55786,P21796,Q9H3P7,P45880
Functions
GO Molecular function
msigdb_gomf
2,188,100,101,6,39,102,131,44,111,50,51,22,24,60,62
896,1157,518,1476,1160,3255,188,1360,2853,1889,101,3356,2150,1021,1481,2153,131,3105,411,2313,1420,2103,2914,1320,1892,2033,1539,1173,24,1898,2507,3038,3083,1800,1545,1031,2796,102,2163,2320,826,1429,1430,50,2956,62,2041,875,448,2509,1432,2472,522,793,719,1966,22,2511,1383,1437,2382,2712,2,2228,111,483,2178,1814,416,2674,2631,1334,2840,288,51,1449,3234,605,6,2002,1398,299,2192,1512,1301,2243,3203,3335,1882,2782,402,3076,60,3337,2072,2452,44,2248,204,2965,772,1016,2204,100,39,1057,3184,2730,1946
0.39259560337501387,0.22829128088385117,0.7116358722612617,0.060467414101225296,0.22829128088385117,-1.609172964600143,1.4623297140439213,0.11681693759758847,-0.771394044942476,-0.14008827619228245,2.092004590409298,-3.224685614946227,-0.2569802644281954,0.31086666228014365,0.060467414101225296,-0.2569802644281954,1.8168408195595176,-1.150739668468142,0.8667959860819097,-0.34571237893882045,0.08869434652356714,-0.2276042406016599,-0.8337145938116572,0.14483658048926837,-0.14008827619228245,-0.1983298434546702,0.03213471430384632,0.22829128088385117,3.356198648789754,-0.14008827619228245,-0.4654106405661174,-1.0228587054425817,-1.0866228857275761,-0.08226034641678645,0.03213471430384632,0.31086666228014365,-0.7094431280794159,2.092004590409298,-0.2569802644281954,-0.34571237893882045,0.44662661518260455,0.08869434652356714,0.08869434652356714,2.622580671152067,-0.8964011979097756,2.514056875953885,-0.1983298434546702,0.41965586752605055,0.8153801473078209,-0.4654106405661174,0.08869434652356714,-0.43533889653030694,0.7116358722612617,0.47350891704813686,0.5270123572912739,-0.16915765752368028,3.4171394805890736,-0.4654106405661174,0.11681693759758847,0.08869434652356714,-0.3754892338100565,-0.6172178657741221,5.239408177537105,-0.28645733903368353,2.0010668397853175,0.7636623002448963,-0.2569802644281954,-0.08226034641678645,0.8667959860819097,-0.5866649642761562,-0.5562072945734238,0.14483658048926837,-0.74037215539053,1.0945945877969334,2.6009562194312528,0.08869434652356714,-1.4765043166587404,0.6330026427578571,4.432259380667763,-0.16915765752368028,0.11681693759758847,1.0695626309218393,-0.2569802644281954,0.060467414101225296,0.17275463656922826,-0.28645733903368353,-1.3778800978198302,-2.502718876001027,-0.11112230190969725,-0.6786074245996516,0.8923926409127418,-1.0546965194844964,2.5358424878703127,-2.502718876001027,-0.1983298434546702,-0.4053649182267038,2.8366888054205845,-0.28645733903368353,1.4382450552811312,-0.8964011979097756,0.5003038219140473,0.33820212925301407,-0.2569802644281954,2.1146206568398127,2.9423357816117885,0.31086666228014365,-1.3125536644868265,-0.6172178657741221,-0.14008827619228245
3,375
Metabolism of steroids
13
44
3.159562
0.00158
P48449,Q9HCL2,Q9H2C2,P37268,Q15436,Q14739,P04062,Q15392,Q9UBM7,P38435,Q16850,Q99538,P04035
Processes and pathways
Reactome Pathways
msigdb_reactome
32,172,404,412,436,174,358,51,57,245,186,92,253
1160,2617,1648,1959,1062,2501,253,358,2315,2831,1718,1898,2737,1176,412,245,32,875,2167,2510,1379,1554,2940,797,1916,724,174,1190,1334,2126,51,436,1335,2635,186,959,1045,1395,1575,92,454,404,172,57
0.22829128088385117,-0.5562072945734238,-0.024850986633067236,-0.16915765752368028,0.28343716336325137,-0.4654106405661174,1.2187556408509548,0.9433672737733582,-0.34571237893882045,-0.74037215539053,-0.05350303097992167,-0.14008827619228245,-0.6478655125716591,0.22829128088385117,0.8667959860819097,1.24339256161293,3.130252972308468,0.41965586752605055,-0.2569802644281954,-0.4654106405661174,0.11681693759758847,0.03213471430384632,-0.8650123589926522,0.47350891704813686,-0.14008827619228245,0.5270123572912739,1.5342340098871912,0.22829128088385117,0.14483658048926837,-0.2276042406016599,2.6009562194312528,0.8411254163810149,0.14483658048926837,-0.5562072945734238,1.486355749287792,0.36544472945786843,0.31086666228014365,0.11681693759758847,0.03213471430384632,2.182190438903513,0.8153801473078209,0.8923926409127418,1.5580872461878,2.5792918852390194
3,375
Golgi membrane
33
135
3.158843
0.001584
O15260,Q8N4V1,O60499,Q9P2W9,O00461,Q14108,Q7LGA3,Q8NBN3,Q9HC07,Q13464,Q10713,Q15436,Q9Y314,Q9Y282,Q13190,Q15392,Q9H3P7,P53367,Q16739,Q9NXE4,O95070,P0CG08,Q8IV08,Q99640,Q9Y296,Q9UHD1,Q969X5,Q9H4A6,O15258,Q9Y678,Q96MW5,Q8NF37,Q8NCH0
Localization
GO Cellular component
msigdb_gocc
9,11,16,150,278,31,289,40,302,42,414,436,442,49,296,51,60,312,78,470,461,340,94,95,497,369,232,367,357,517,247,508,126
3008,278,1949,645,820,357,9,1651,1531,2790,1590,2023,16,1845,2967,461,588,1024,3060,3105,1169,340,1892,651,869,3036,1718,3061,1325,3062,3093,2217,1548,1034,1864,1431,621,2044,503,2708,2220,793,312,1967,595,1908,1736,1970,2329,2512,952,1738,2862,3136,2863,2381,1866,2383,2477,2514,1441,955,1073,414,2286,296,42,31,1675,2436,1563,2389,51,436,78,3270,1290,2925,289,1044,3023,1821,2751,94,1615,11,2397,40,126,695,508,762,2846,1049,2001,964,232,3310,1685,247,3222,95,3003,2813,2532,1053,1466,1145,60,367,3337,1632,768,302,610,549,1215,470,2144,150,1582,740,369,894,1637,2494,3109,49,497,1584,442,2762,1258,1101,517
-0.9911098512078583,1.1195590959099642,-0.16915765752368028,0.5801743268480191,0.44662661518260455,0.9433672737733582,4.069826366870343,-0.024850986633067236,0.03213471430384632,-0.7094431280794159,0.0036951455715587326,-0.1983298434546702,3.697871107665648,-0.11112230190969725,-0.9278806773204062,0.7895593798784971,0.6330026427578571,0.31086666228014365,-1.0546965194844964,-1.150739668468142,0.22829128088385117,0.9940553151106681,-0.14008827619228245,0.5801743268480191,0.41965586752605055,-1.0228587054425817,-0.05350303097992167,-1.0546965194844964,0.14483658048926837,-1.0546965194844964,-1.1186374013991909,-0.28645733903368353,0.03213471430384632,0.31086666228014365,-0.11112230190969725,0.08869434652356714,0.6066297150102449,-0.1983298434546702,0.7376880792986121,-0.6172178657741221,-0.28645733903368353,0.47350891704813686,1.0444625558272569,-0.16915765752368028,0.6330026427578571,-0.14008827619228245,-0.05350303097992167,-0.16915765752368028,-0.34571237893882045,-0.4654106405661174,0.36544472945786843,-0.05350303097992167,-0.771394044942476,-1.2152058878452634,-0.771394044942476,-0.3754892338100565,-0.11112230190969725,-0.3754892338100565,-0.43533889653030694,-0.4654106405661174,0.08869434652356714,0.36544472945786843,0.28343716336325137,0.8667959860819097,-0.3160348969490162,1.0695626309218393,2.857891489435327,3.1509596999717213,-0.024850986633067236,-0.4053649182267038,0.03213471430384632,-0.3754892338100565,2.6009562194312528,0.8411254163810149,2.2716465763795988,-1.6760024115861647,0.17275463656922826,-0.8337145938116572,1.0945945877969334,0.31086666228014365,-0.9911098512078583,-0.08226034641678645,-0.6478655125716591,2.159713234494772,0.0036951455715587326,3.9339465846713644,-0.3754892338100565,2.9001864623733686,1.8631989005372565,0.5536355300185024,0.7376880792986121,0.5003038219140473,-0.74037215539053,0.31086666228014365,-0.16915765752368028,0.36544472945786843,1.292476019958997,-2.0493327505938783,-0.024850986633067236,1.24339256161293,-1.4435454454021128,2.159713234494772,-0.9594503693142111,-0.7094431280794159,-0.4654106405661174,0.31086666228014365,0.08869434652356714,0.25591244186398043,2.5358424878703127,0.9433672737733582,-2.502718876001027,0.0036951455715587326,0.5003038219140473,1.0695626309218393,0.6330026427578571,0.6855048182603979,0.22829128088385117,0.7895593798784971,-0.2276042406016599,1.700034827064007,0.03213471430384632,0.5270123572912739,0.9433672737733582,0.41965586752605055,0.0036951455715587326,-0.43533889653030694,-1.150739668468142,2.6441655068947094,0.7636623002448963,0.03213471430384632,0.8411254163810149,-0.6478655125716591,0.2005724364337766,0.28343716336325137,0.7376880792986121
3,375
Lipid biosynthesis
12
57
3.154156
0.00161
P48449,Q9HCL2,Q96G23,P35790,P48651,Q14739,Q16739,Q9C0D9,Q15392,Q9UBM7,Q16850,Q9H3P7
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
32,172,70,13,141,174,78,109,51,57,186,60
1103,1160,2617,1162,1361,903,1536,253,2033,2315,13,412,32,141,875,1180,2510,1969,2940,797,1038,1916,174,2126,2865,51,1335,2635,78,186,959,2130,3152,1395,508,2959,1571,2898,2870,2005,70,453,2244,3026,2298,385,109,60,3337,172,2142,1255,1636,613,57,854,1841
0.25591244186398043,0.22829128088385117,-0.5562072945734238,0.22829128088385117,0.11681693759758847,0.39259560337501387,0.03213471430384632,1.2187556408509548,-0.1983298434546702,-0.34571237893882045,3.7572720143403053,0.8667959860819097,3.130252972308468,1.7235018312297918,0.41965586752605055,0.22829128088385117,-0.4654106405661174,-0.16915765752368028,-0.8650123589926522,0.47350891704813686,0.31086666228014365,-0.14008827619228245,1.5342340098871912,-0.2276042406016599,-0.771394044942476,2.6009562194312528,0.14483658048926837,-0.5562072945734238,2.2716465763795988,1.486355749287792,0.36544472945786843,-0.2276042406016599,-1.2475690670035406,0.11681693759758847,0.7376880792986121,-0.8964011979097756,0.03213471430384632,-0.8025083410499405,-0.771394044942476,-0.16915765752368028,2.426501785073673,0.8153801473078209,-0.28645733903368353,-0.9911098512078583,-0.3160348969490162,0.91791615126421,2.0238730257815676,2.5358424878703127,-2.502718876001027,1.5580872461878,-0.2276042406016599,0.2005724364337766,0.0036951455715587326,0.6330026427578571,2.5792918852390194,0.44662661518260455,-0.08226034641678645
3,375
Sloping forehead
25
49
3.153334
0.001614
Q9H936,Q15003,Q00534,P23786,Q8IZT6,Q9BXW9,P08243,Q86XL3,Q96EK5,Q96SN8,O60566,Q9BSJ2,P26640,Q9HC21,A5YKK6,Q92917,O14936,Q02224,Q9NXE4,P42695,Q96KP1,O95630,O15360,Q9H9E3,Q15021
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
930,798,274,20,25,292,539,170,574,843,431,845,685,192,939,729,819,953,470,83,1008,589,477,768,628
939,1948,819,477,1530,1223,1020,431,2659,589,539,20,685,1325,83,1327,1279,1734,1384,274,953,1187,1281,1188,1915,798,628,1236,1565,2289,170,25,2348,729,2293,2242,574,1008,843,845,292,2012,930,768,192,1696,1014,470,2256
0.36544472945786843,-0.16915765752368028,0.44662661518260455,0.7636623002448963,0.03213471430384632,0.2005724364337766,0.31086666228014365,0.8411254163810149,-0.5866649642761562,0.6330026427578571,0.6855048182603979,3.457609530408841,0.5536355300185024,0.14483658048926837,2.249349781196953,0.14483658048926837,0.17275463656922826,-0.05350303097992167,0.11681693759758847,1.144456813443884,0.36544472945786843,0.22829128088385117,0.17275463656922826,0.22829128088385117,-0.14008827619228245,0.47350891704813686,0.6066297150102449,0.2005724364337766,0.03213471430384632,-0.3160348969490162,1.5580872461878,3.335821452262717,-0.34571237893882045,0.5270123572912739,-0.3160348969490162,-0.28645733903368353,0.6592940398904245,0.33820212925301407,0.44662661518260455,0.44662661518260455,1.0945945877969334,-0.16915765752368028,0.39259560337501387,0.5003038219140473,1.4623297140439213,-0.024850986633067236,0.33820212925301407,0.7895593798784971,-0.28645733903368353
3,375
Mitochondrial transmembrane transport
21
55
3.130071
0.001748
O60830,O43772,Q9BSK2,P23786,O75964,P21796,Q99595,P00846,P53007,P12236,O14925,Q15388,Q6P4A7,P12235,P50416,P56134,Q9Y619,Q9H2D1,Q00325,Q9NUT2,Q9BQT8
Processes and pathways
GO Biological process
msigdb_gobp
0,15,18,20,393,24,28,156,162,541,284,288,568,54,311,561,475,81,598,495,490
284,2370,15,0,1022,1787,1847,3146,393,2153,2027,616,1850,1264,156,865,3134,3237,54,541,24,20,2109,3037,2916,3135,311,162,561,2474,598,288,800,881,568,3107,1823,1242,2927,1005,3272,1760,28,1626,490,18,81,930,1884,3077,495,2205,2729,2018,475
1.0945945877969334,-0.3754892338100565,3.697871107665648,6.177852396500397,0.31086666228014365,-0.08226034641678645,-0.11112230190969725,-1.2475690670035406,0.8923926409127418,-0.2569802644281954,-0.1983298434546702,0.6066297150102449,-0.11112230190969725,0.17275463656922826,1.6293092873800175,0.41965586752605055,-1.2152058878452634,-1.5095468498520557,2.5792918852390194,0.6855048182603979,3.356198648789754,3.457609530408841,-0.2276042406016599,-1.0228587054425817,-0.8337145938116572,-1.2152058878452634,1.0444625558272569,1.5818838811891258,0.6592940398904245,-0.43533889653030694,0.6330026427578571,1.0945945877969334,0.47350891704813686,0.41965586752605055,0.6592940398904245,-1.150739668468142,-0.08226034641678645,0.2005724364337766,-0.8337145938116572,0.33820212925301407,-1.6760024115861647,-0.05350303097992167,3.294970582891578,0.0036951455715587326,0.7636623002448963,3.6780129047155596,2.2716465763795988,0.39259560337501387,-0.11112230190969725,-1.0546965194844964,0.7636623002448963,-0.2569802644281954,-0.6172178657741221,-0.16915765752368028,0.7895593798784971
3,375
Lipid metabolic process
64
281
3.126373
0.00177
P14174,Q8WTV0,Q8NCC3,Q9H2C2,P04066,P09455,P35790,P48651,P31751,P23786,Q06136,A1L0T0,P48449,Q9NPH0,Q99805,Q9HCL2,O15118,Q10713,P37268,P05067,Q14914,Q14739,Q9H6V9,Q15392,Q8WXW3,Q9UBM7,Q6IAN0,P50897,P06280,Q16850,Q9H3P7,P50416,Q2TAA5,Q9NRA0,Q9BWD1,Q9HB40,O14773,Q9Y263,Q96N66,Q96G23,P49748,O94788,P07099,Q16739,P16278,Q9NXE4,Q9BYI3,O75844,Q99538,Q8TC12,Q86YN1,Q8NHP8,Q6NUM9,P35610,Q9UHD1,Q9BY49,Q9BT22,Q9C0D9,P04062,Q8NBX0,P38435,O75376,P04035,Q9Y394
Processes and pathways
GO Biological process
msigdb_gobp
255,6,7,404,266,267,13,141,148,20,280,391,32,35,36,172,285,414,412,166,45,174,48,51,318,57,315,55,432,186,60,311,313,193,454,67,188,338,453,70,448,75,76,78,207,470,86,88,92,226,224,99,223,102,369,385,365,109,358,120,245,252,253,127
391,857,1103,896,1220,1160,2617,1221,1648,1162,188,976,285,1361,1163,2418,1164,2987,3133,3367,683,1314,1478,782,1953,2909,710,2095,252,1954,1481,2152,88,2764,75,3112,1484,1316,983,2501,2212,903,1536,253,358,266,2156,2461,166,2313,2102,432,3134,684,76,1420,3218,2580,267,2269,3327,1657,2033,1266,1225,3190,255,2315,2463,2831,3333,207,1540,2971,3257,2034,3293,715,3219,907,1718,1898,2737,20,2377,3037,2378,1800,653,2110,2702,789,1176,148,3317,988,102,13,1659,412,2937,245,3264,1429,2665,1034,1177,1118,2380,873,2321,32,141,1431,875,751,448,311,522,55,2801,2919,1120,2167,794,1180,2510,657,1969,3041,2552,1970,3298,1973,2175,2940,1669,1912,1385,1386,877,280,414,3084,797,1038,2890,1916,918,724,174,1190,45,1039,799,3096,1390,2438,2126,2865,51,1445,1335,2635,1129,2440,78,1980,663,186,313,3233,959,1503,1449,2520,315,223,1747,2130,2341,3152,1133,2926,2716,224,529,1753,805,2869,3371,839,1395,120,7,1996,508,99,226,6,2959,1571,1619,318,2898,2870,2720,2002,1462,1007,2005,3272,926,70,453,3127,2809,2562,1575,92,1687,3203,3052,3335,36,1209,2244,365,2564,1304,3373,3026,454,2298,2299,385,86,3055,109,404,60,1148,2070,48,3337,2072,67,172,35,2142,2930,193,3079,1215,2986,1255,675,551,470,1636,2965,772,613,2144,740,57,678,854,2950,369,933,1841,473,2729,2206,2082,1311,338,127,1946,2417
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3,375
Hormone metabolic process
8
30
3.091933
0.001989
Q8TC12,Q9HB40,Q6NUM9,O94788,P42892,Q9UBM7,O75844,Q9Y394
Processes and pathways
GO Biological process
msigdb_gobp
226,67,223,75,50,57,88,127
782,1848,88,75,1316,2461,267,1539,2831,1540,715,1176,50,1907,2167,877,1190,959,223,839,1395,226,2898,2526,3052,1304,67,57,1311,127
0.47350891704813686,-0.11112230190969725,2.2046220417723954,2.3382725296462423,0.14483658048926837,-0.43533889653030694,1.1692883875750077,0.03213471430384632,-0.74037215539053,0.03213471430384632,0.5270123572912739,0.22829128088385117,2.622580671152067,-0.14008827619228245,-0.2569802644281954,0.41965586752605055,0.22829128088385117,0.36544472945786843,1.3169237397506999,0.44662661518260455,0.11681693759758847,1.3169237397506999,-0.8025083410499405,-0.4654106405661174,-1.0228587054425817,0.17275463656922826,2.4922302839791723,2.5792918852390194,0.17275463656922826,1.8631989005372565
3,375
Organophosphate ester transport
8
29
3.08844
0.002012
Q86VD7,Q8WTV0,Q9H2D1,Q9BSK2,Q96GC9,P08183,P12235,Q14108
Processes and pathways
GO Biological process
msigdb_gobp
133,6,81,18,84,53,54,31
3255,1709,1314,865,53,54,541,1718,1898,1430,1431,3298,3066,31,360,1291,1614,133,762,530,6,84,18,3055,81,192,2965,2144,1946
-1.609172964600143,-0.05350303097992167,0.14483658048926837,0.41965586752605055,2.5792918852390194,2.5792918852390194,0.6855048182603979,-0.05350303097992167,-0.14008827619228245,0.08869434652356714,0.08869434652356714,-1.9465598176439003,-1.0546965194844964,3.1509596999717213,0.9433672737733582,0.17275463656922826,0.0036951455715587326,1.8168408195595176,0.5003038219140473,0.7116358722612617,4.432259380667763,2.249349781196953,3.6780129047155596,-1.0228587054425817,2.2716465763795988,1.4623297140439213,-0.8964011979097756,-0.2276042406016599,-0.14008827619228245
3,375
Glycerophospholipid biosynthesis
6
29
3.053692
0.00226
Q9NPH0,Q8NCC3,P35790,P48651,Q9C0D9,Q8IV08
Processes and pathways
Reactome Pathways
msigdb_reactome
35,7,13,141,109,94
1162,1163,1224,1489,13,1429,1274,141,1431,3041,1740,1503,2130,94,7,508,2959,1619,2870,453,1209,2244,3026,3055,109,172,35,1255,854
0.22829128088385117,0.22829128088385117,0.2005724364337766,0.060467414101225296,3.7572720143403053,0.08869434652356714,0.17275463656922826,1.7235018312297918,0.08869434652356714,-1.0228587054425817,-0.05350303097992167,0.060467414101225296,-0.2276042406016599,2.159713234494772,4.337756409373861,0.7376880792986121,-0.8964011979097756,0.0036951455715587326,-0.771394044942476,0.8153801473078209,0.22829128088385117,-0.28645733903368353,-0.9911098512078583,-1.0228587054425817,2.0238730257815676,1.5580872461878,3.0887372059217104,0.2005724364337766,0.44662661518260455
3,375
Organic anion transmembrane transporter activity
13
33
3.042623
0.002345
P11166,P53007,P12236,Q14728,Q9BQT8,Q86VD7,Q9Y619,Q9H2D1,Q9UBX3,P30825,P12235,O95563,Q9HC21
Functions
GO Molecular function
msigdb_gomf
651,162,541,355,490,133,475,81,144,85,54,616,192
2539,1709,1314,1847,616,865,2373,651,54,541,85,1430,162,657,1280,355,2557,1291,1614,1747,133,762,1760,490,81,930,1884,192,144,2205,2904,475,1586
-0.49557962951464074,-0.05350303097992167,0.14483658048926837,-0.11112230190969725,0.6066297150102449,0.41965586752605055,-0.3754892338100565,0.5801743268480191,2.5792918852390194,0.6855048182603979,2.2270083787382036,0.08869434652356714,1.5818838811891258,0.5801743268480191,0.17275463656922826,0.9687467516697891,-0.49557962951464074,0.17275463656922826,0.0036951455715587326,-0.05350303097992167,1.8168408195595176,0.5003038219140473,-0.05350303097992167,0.7636623002448963,2.2716465763795988,0.39259560337501387,-0.11112230190969725,1.4623297140439213,1.7235018312297918,-0.2569802644281954,-0.8025083410499405,0.7895593798784971,0.03213471430384632
3,375
Phospholipid binding
21
97
3.038516
0.002377
Q8WTV0,Q8NCC3,Q9Y4P8,Q9Y4G8,Q7Z3T8,P12429,P21796,Q14108,Q9UM22,Q9UKG1,P50897,P45880,P53367,O14773,O60784,Q13576,Q96BY7,P53365,Q96L92,Q9H4A6,Q8N3F8
Functions
GO Molecular function
msigdb_gomf
6,7,409,14,143,394,24,31,39,184,55,62,312,188,460,463,487,353,488,367,124
2696,1158,1220,1708,3255,188,1104,2262,1785,3225,1108,1532,2092,1952,460,1224,1167,2156,2953,1420,823,2031,1891,2828,2314,2270,394,2107,24,1718,1030,2467,62,2549,1377,1431,55,2323,353,312,2118,878,1557,956,2631,463,1673,31,2052,2436,1039,2775,2337,3168,143,803,2718,124,3051,7,6,1049,2720,1683,1300,487,488,1209,807,2067,608,3055,637,2565,1148,367,766,1699,2965,772,1353,515,3006,2729,184,3301,39,1778,2495,1944,937,2416,14,409,1946,2457,2695
-0.6172178657741221,0.22829128088385117,0.2005724364337766,-0.05350303097992167,-1.609172964600143,1.4623297140439213,0.25591244186398043,-0.3160348969490162,-0.08226034641678645,-1.4765043166587404,0.25591244186398043,0.03213471430384632,-0.2276042406016599,-0.16915765752368028,0.7895593798784971,0.2005724364337766,0.22829128088385117,-0.2569802644281954,-0.8964011979097756,0.08869434652356714,0.44662661518260455,-0.1983298434546702,-0.14008827619228245,-0.74037215539053,-0.34571237893882045,-0.3160348969490162,0.8923926409127418,-0.2276042406016599,3.356198648789754,-0.05350303097992167,0.31086666228014365,-0.43533889653030694,2.514056875953885,-0.49557962951464074,0.11681693759758847,0.08869434652356714,2.5792918852390194,-0.34571237893882045,0.9687467516697891,1.0444625558272569,-0.2276042406016599,0.41965586752605055,0.03213471430384632,0.36544472945786843,-0.5562072945734238,0.7895593798784971,-0.024850986633067236,3.1509596999717213,-0.1983298434546702,-0.4053649182267038,0.31086666228014365,-0.6786074245996516,-0.34571237893882045,-1.2800184510915182,1.7235018312297918,0.47350891704813686,-0.6172178657741221,1.8863015470497642,-1.0228587054425817,4.337756409373861,4.432259380667763,0.31086666228014365,-0.6172178657741221,-0.024850986633067236,0.17275463656922826,0.7636623002448963,0.7636623002448963,0.22829128088385117,0.47350891704813686,-0.1983298434546702,0.6330026427578571,-1.0228587054425817,0.6066297150102449,-0.49557962951464074,0.25591244186398043,0.9433672737733582,0.5003038219140473,-0.024850986633067236,-0.8964011979097756,0.5003038219140473,0.14483658048926837,0.7376880792986121,-0.9594503693142111,-0.6172178657741221,1.5103236781354623,-1.9465598176439003,2.9423357816117885,-0.05350303097992167,-0.43533889653030694,-0.14008827619228245,0.39259560337501387,-0.3754892338100565,3.737500508749279,0.8923926409127418,-0.14008827619228245,-0.4053649182267038,-0.5866649642761562
3,375
FDA approved drug targets
42
126
3.033728
0.002416
O75330,P00374,P20645,P05091,Q99720,Q00534,P49069,P23786,P20618,P12429,Q16836,P00390,P12236,Q13464,P39023,P05067,P04818,Q8N0U8,Q13423,P12235,Q16850,P50416,P49721,P11274,P28074,Q7L0J3,Q99707,P03886,Q13547,P21281,P00813,Q16739,Q14534,P19838,O75116,P12277,P35610,P10253,P38435,P49356,P04035,P23921
Functions
Protein Atlas Protein class
protein_atlas_protein_class
501,131,137,746,12,274,272,20,147,394,663,649,541,42,655,166,411,437,435,54,186,311,59,556,557,69,336,71,563,446,326,78,724,715,709,590,102,231,245,751,253,618
1528,1105,2934,709,501,2764,2501,903,1419,131,649,2936,2265,326,1113,71,253,2156,2266,411,2461,166,746,865,2734,1851,2953,1026,2580,2828,1853,785,231,556,2462,1960,1225,54,541,2505,590,394,3114,1114,1267,2315,1539,2831,1064,870,715,1541,147,137,1171,446,1857,907,1897,908,20,618,787,1799,2161,557,2379,2991,2702,1545,1901,1546,1272,102,1660,1801,245,655,2861,1034,948,2041,3307,272,875,3160,751,59,2165,311,1180,1969,2168,830,1072,2383,274,3164,2384,1741,2048,753,1038,435,42,563,1868,724,2748,1390,2557,1129,921,78,663,186,1872,69,437,1006,1344,336,3052,12,1352,3028
0.03213471430384632,0.25591244186398043,-0.8650123589926522,0.5270123572912739,0.7376880792986121,-0.6786074245996516,-0.4654106405661174,0.39259560337501387,0.08869434652356714,1.8168408195595176,0.5801743268480191,-0.8650123589926522,-0.3160348969490162,1.0192936815049485,0.25591244186398043,2.404508413104643,1.2187556408509548,-0.2569802644281954,-0.3160348969490162,0.8667959860819097,-0.43533889653030694,1.5580872461878,0.5003038219140473,0.41965586752605055,-0.6478655125716591,-0.11112230190969725,-0.8964011979097756,0.31086666228014365,-0.5258453497283577,-0.74037215539053,-0.11112230190969725,0.47350891704813686,1.292476019958997,0.6592940398904245,-0.43533889653030694,-0.16915765752368028,0.2005724364337766,2.5792918852390194,0.6855048182603979,-0.4654106405661174,0.6330026427578571,0.8923926409127418,-1.1829292935550804,0.25591244186398043,0.17275463656922826,-0.34571237893882045,0.03213471430384632,-0.74037215539053,0.28343716336325137,0.41965586752605055,0.5270123572912739,0.03213471430384632,1.700034827064007,1.7935845599756126,0.22829128088385117,0.8153801473078209,-0.11112230190969725,0.39259560337501387,-0.14008827619228245,0.39259560337501387,3.457609530408841,0.6066297150102449,0.47350891704813686,-0.08226034641678645,-0.2569802644281954,0.6592940398904245,-0.3754892338100565,-0.9594503693142111,-0.6172178657741221,0.03213471430384632,-0.14008827619228245,0.03213471430384632,0.17275463656922826,2.092004590409298,-0.024850986633067236,-0.08226034641678645,1.24339256161293,0.5801743268480191,-0.771394044942476,0.31086666228014365,0.36544472945786843,-0.1983298434546702,-2.0493327505938783,1.144456813443884,0.41965586752605055,-1.2800184510915182,0.5003038219140473,2.5358424878703127,-0.2569802644281954,1.0444625558272569,0.22829128088385117,-0.16915765752368028,-0.2569802644281954,0.44662661518260455,0.28343716336325137,-0.3754892338100565,1.144456813443884,-1.2800184510915182,-0.3754892338100565,-0.05350303097992167,-0.1983298434546702,0.5003038219140473,0.31086666228014365,0.8411254163810149,2.857891489435327,0.6592940398904245,-0.11112230190969725,0.5270123572912739,-0.6478655125716591,0.11681693759758847,-0.49557962951464074,0.25591244186398043,0.39259560337501387,2.2716465763795988,0.5801743268480191,1.486355749287792,-0.11112230190969725,2.4484530262047968,0.8411254163810149,0.33820212925301407,0.14483658048926837,1.0192936815049485,-1.0228587054425817,3.9144271277439557,0.14483658048926837,-0.9911098512078583
3,375
FDA approved drug targets
42
126
3.033728
0.002416
O75330,P00374,P20645,P05091,Q99720,Q00534,P49069,P23786,P20618,P12429,Q16836,P00390,P12236,Q13464,P39023,P05067,P04818,Q8N0U8,Q13423,P12235,Q16850,P50416,P49721,P11274,P28074,Q7L0J3,Q99707,P03886,Q13547,P21281,P00813,Q16739,Q14534,P19838,O75116,P12277,P35610,P10253,P38435,P49356,P04035,P23921
Drugs and Diseases
Protein Atlas Disease involvement
protein_atlas_disease_involvement
501,131,137,746,12,274,272,20,147,394,663,649,541,42,655,166,411,437,435,54,186,311,59,556,557,69,336,71,563,446,326,78,724,715,709,590,102,231,245,751,253,618
1528,1105,2934,709,501,2764,2501,903,1419,131,649,2936,2265,326,1113,71,253,2156,2266,411,2461,166,746,865,2734,1851,2953,1026,2580,2828,1853,785,231,556,2462,1960,1225,54,541,2505,590,394,3114,1114,1267,2315,1539,2831,1064,870,715,1541,147,137,1171,446,1857,907,1897,908,20,618,787,1799,2161,557,2379,2991,2702,1545,1901,1546,1272,102,1660,1801,245,655,2861,1034,948,2041,3307,272,875,3160,751,59,2165,311,1180,1969,2168,830,1072,2383,274,3164,2384,1741,2048,753,1038,435,42,563,1868,724,2748,1390,2557,1129,921,78,663,186,1872,69,437,1006,1344,336,3052,12,1352,3028
0.03213471430384632,0.25591244186398043,-0.8650123589926522,0.5270123572912739,0.7376880792986121,-0.6786074245996516,-0.4654106405661174,0.39259560337501387,0.08869434652356714,1.8168408195595176,0.5801743268480191,-0.8650123589926522,-0.3160348969490162,1.0192936815049485,0.25591244186398043,2.404508413104643,1.2187556408509548,-0.2569802644281954,-0.3160348969490162,0.8667959860819097,-0.43533889653030694,1.5580872461878,0.5003038219140473,0.41965586752605055,-0.6478655125716591,-0.11112230190969725,-0.8964011979097756,0.31086666228014365,-0.5258453497283577,-0.74037215539053,-0.11112230190969725,0.47350891704813686,1.292476019958997,0.6592940398904245,-0.43533889653030694,-0.16915765752368028,0.2005724364337766,2.5792918852390194,0.6855048182603979,-0.4654106405661174,0.6330026427578571,0.8923926409127418,-1.1829292935550804,0.25591244186398043,0.17275463656922826,-0.34571237893882045,0.03213471430384632,-0.74037215539053,0.28343716336325137,0.41965586752605055,0.5270123572912739,0.03213471430384632,1.700034827064007,1.7935845599756126,0.22829128088385117,0.8153801473078209,-0.11112230190969725,0.39259560337501387,-0.14008827619228245,0.39259560337501387,3.457609530408841,0.6066297150102449,0.47350891704813686,-0.08226034641678645,-0.2569802644281954,0.6592940398904245,-0.3754892338100565,-0.9594503693142111,-0.6172178657741221,0.03213471430384632,-0.14008827619228245,0.03213471430384632,0.17275463656922826,2.092004590409298,-0.024850986633067236,-0.08226034641678645,1.24339256161293,0.5801743268480191,-0.771394044942476,0.31086666228014365,0.36544472945786843,-0.1983298434546702,-2.0493327505938783,1.144456813443884,0.41965586752605055,-1.2800184510915182,0.5003038219140473,2.5358424878703127,-0.2569802644281954,1.0444625558272569,0.22829128088385117,-0.16915765752368028,-0.2569802644281954,0.44662661518260455,0.28343716336325137,-0.3754892338100565,1.144456813443884,-1.2800184510915182,-0.3754892338100565,-0.05350303097992167,-0.1983298434546702,0.5003038219140473,0.31086666228014365,0.8411254163810149,2.857891489435327,0.6592940398904245,-0.11112230190969725,0.5270123572912739,-0.6478655125716591,0.11681693759758847,-0.49557962951464074,0.25591244186398043,0.39259560337501387,2.2716465763795988,0.5801743268480191,1.486355749287792,-0.11112230190969725,2.4484530262047968,0.8411254163810149,0.33820212925301407,0.14483658048926837,1.0192936815049485,-1.0228587054425817,3.9144271277439557,0.14483658048926837,-0.9911098512078583
3,375
Receptor
6
30
2.999802
0.002702
Q8WTV0,P20645,Q567V2,Q9UQB8,Q9NR77,Q14108
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
6,137,23,90,61,31
138,1105,1590,1848,2096,1714,2734,869,137,2470,1494,2630,331,543,31,2390,23,2998,1239,6,1617,1757,533,455,2929,61,2412,680,2692,90
1.7702762612399765,0.25591244186398043,0.0036951455715587326,-0.11112230190969725,-0.2276042406016599,-0.05350303097992167,-0.6478655125716591,0.41965586752605055,1.7935845599756126,-0.43533889653030694,0.060467414101225296,-0.5562072945734238,1.0192936815049485,0.6855048182603979,3.1509596999717213,-0.3754892338100565,3.3968574822924804,-0.9594503693142111,0.2005724364337766,4.432259380667763,0.0036951455715587326,-0.05350303097992167,0.7116358722612617,0.8153801473078209,-0.8337145938116572,2.5358424878703127,-0.3754892338100565,0.5801743268480191,-0.5866649642761562,2.2046220417723954
3,375
Protein targeting to membrane
21
36
2.942133
0.00326
Q9H9H4,Q86YS7,Q9Y4C2,P31751,P50542,O00159,Q15629,Q99442,O43681,Q7L5D6,P40855,O60725,Q9GZY8,Q00535,Q9UHB9,P46379,P43307,Q9UHD1,P27105,Q9H0F7,Q8N3F8
Processes and pathways
GO Biological process
msigdb_gobp
673,803,681,148,522,897,154,577,683,837,826,82,734,599,1016,91,593,369,479,637,124
974,897,1708,683,1951,82,1263,2422,479,1860,148,2320,826,593,91,2798,522,1735,2511,1383,599,1557,1288,154,837,803,124,577,734,637,673,1254,1775,1016,369,681
0.33820212925301407,0.39259560337501387,-0.05350303097992167,0.5536355300185024,-0.16915765752368028,2.249349781196953,0.17275463656922826,-0.4053649182267038,0.7636623002448963,-0.11112230190969725,1.700034827064007,-0.34571237893882045,0.44662661518260455,0.6330026427578571,2.182190438903513,-0.7094431280794159,0.7116358722612617,-0.05350303097992167,-0.4654106405661174,0.11681693759758847,0.6330026427578571,0.03213471430384632,0.17275463656922826,1.6529390108089894,0.44662661518260455,0.47350891704813686,1.8863015470497642,0.6592940398904245,0.5270123572912739,0.6066297150102449,0.5801743268480191,0.2005724364337766,-0.05350303097992167,0.33820212925301407,0.9433672737733582,0.5801743268480191
3,375
Protein kinase-like domain superfamily [IPR011009]
28
77
2.908633
0.00363
P78527,Q13546,Q16512,P21127,P35790,Q00534,P31751,P49840,P49841,Q9HA64,Q13464,Q96SB4,Q9UHD2,Q8TD19,Q6P3W7,O60566,Q9H4A3,Q14012,O14936,Q9UBF8,P48729,Q13418,Q00535,O75116,Q99640,Q8NI60,P17252,Q13555
Sequence
InterPro Superfamily
interpro_homologous_superfamily
375,626,756,268,13,274,148,273,157,171,42,576,704,298,297,431,849,564,819,740,827,723,599,709,95,509,870,505
1220,1948,1058,819,977,1166,1223,431,709,1370,2372,1225,870,1794,2584,1489,268,1373,1799,2379,148,1724,13,1801,1904,1034,827,273,157,1662,1730,1179,3230,375,274,599,1741,1385,2180,1038,1442,2745,1914,723,42,2774,626,505,564,1041,2232,756,2127,2440,297,2341,1567,1749,962,2346,509,298,1247,928,576,1687,95,2447,1517,1350,849,171,2567,740,704,1702,1359
0.2005724364337766,-0.16915765752368028,0.28343716336325137,0.44662661518260455,0.33820212925301407,0.22829128088385117,0.2005724364337766,0.8411254163810149,0.5270123572912739,0.11681693759758847,-0.3754892338100565,0.2005724364337766,0.41965586752605055,-0.08226034641678645,-0.5258453497283577,0.060467414101225296,1.1692883875750077,0.11681693759758847,-0.08226034641678645,-0.3754892338100565,1.700034827064007,-0.05350303097992167,3.7572720143403053,-0.08226034641678645,-0.14008827619228245,0.31086666228014365,0.44662661518260455,1.144456813443884,1.6293092873800175,-0.024850986633067236,-0.05350303097992167,0.22829128088385117,-1.4765043166587404,0.91791615126421,1.144456813443884,0.6330026427578571,-0.05350303097992167,0.11681693759758847,-0.2569802644281954,0.31086666228014365,0.08869434652356714,-0.6478655125716591,-0.14008827619228245,0.5270123572912739,2.857891489435327,-0.6786074245996516,0.6066297150102449,0.7376880792986121,0.6592940398904245,0.31086666228014365,-0.28645733903368353,0.5003038219140473,-0.2276042406016599,-0.4053649182267038,1.0695626309218393,-0.34571237893882045,0.03213471430384632,-0.05350303097992167,0.36544472945786843,-0.34571237893882045,0.7376880792986121,1.0695626309218393,0.2005724364337766,0.39259560337501387,0.6592940398904245,-0.024850986633067236,2.159713234494772,-0.4053649182267038,0.060467414101225296,0.14483658048926837,0.44662661518260455,1.5580872461878,-0.49557962951464074,0.5270123572912739,0.5536355300185024,-0.024850986633067236,0.14483658048926837
3,375
Lysosome
20
50
2.905589
0.003666
Q8NCC3,P20645,P04066,Q93050,Q14108,P11117,P61421,O15118,P06280,P50897,O14773,P10619,P16278,Q99538,O75503,Q9UI12,P54802,P10253,P04062,Q9UMR5
Processes and pathways
KEGG Pathways
msigdb_kegg
7,137,266,155,31,286,287,285,432,55,188,196,207,92,98,235,480,231,358,122
858,3187,645,188,285,683,1590,98,358,266,432,684,1420,3218,650,2914,1320,231,196,286,2105,869,2856,207,2034,137,3264,55,480,287,3298,3136,1037,1073,2890,31,1336,7,155,1516,92,1466,772,235,515,3006,122,2692,1405,741
0.41965586752605055,-1.3451743358044173,0.5801743268480191,1.4623297140439213,1.0945945877969334,0.5536355300185024,0.0036951455715587326,2.1146206568398127,0.9433672737733582,1.1692883875750077,0.8411254163810149,0.5536355300185024,0.08869434652356714,-1.4435454454021128,0.5801743268480191,-0.8337145938116572,0.14483658048926837,1.292476019958997,1.4382450552811312,1.0945945877969334,-0.2276042406016599,0.41965586752605055,-0.771394044942476,1.3898977585599475,-0.1983298434546702,1.7935845599756126,-1.6425467075224687,2.5792918852390194,0.7636623002448963,1.0945945877969334,-1.9465598176439003,-1.2152058878452634,0.31086666228014365,0.28343716336325137,-0.8025083410499405,3.1509596999717213,0.14483658048926837,4.337756409373861,1.6529390108089894,0.060467414101225296,2.182190438903513,0.08869434652356714,0.5003038219140473,1.292476019958997,0.7376880792986121,-0.9594503693142111,1.9093538048745637,-0.5866649642761562,0.11681693759758847,0.5270123572912739
3,375
Lipid binding
33
152
2.891782
0.003831
Q8WTV0,Q8NCC3,A6NIH7,P09455,Q9Y4P8,Q9Y4G8,Q7Z3T8,P12429,P21796,Q14108,O15118,Q9UM22,Q9UKG1,P50897,P45880,P53367,O14773,O15173,Q13432,O94788,P63167,P28070,O60784,Q13576,Q96BY7,P53365,Q96T51,P35610,Q96L92,Q9H4A6,P04062,P38435,Q8N3F8
Functions
GO Molecular function
msigdb_gomf
6,7,138,267,409,14,143,394,24,31,285,39,184,55,62,312,188,195,331,75,197,205,460,463,487,353,489,102,488,367,358,245,124
2696,138,1157,1158,1475,1220,1708,3255,1162,188,1104,2262,285,195,2418,1785,3225,1108,1532,2092,1952,460,1224,3326,1167,1954,75,3112,2096,944,358,2156,2461,2953,1420,823,2031,1891,267,2828,3237,2314,2270,2581,869,1266,394,2107,24,1718,1898,1658,1425,205,1800,1030,1176,102,2467,245,62,2549,1377,1431,55,2323,794,1434,353,312,2802,2327,3358,3161,3298,197,2175,2118,878,1498,1557,956,2229,331,2631,463,1673,31,2052,1190,2436,1039,799,2775,2337,1449,3168,1567,143,803,2718,124,3051,7,6,1049,2720,1683,1300,487,1512,1514,488,1575,489,2194,3203,1209,2947,807,1882,2067,608,1012,3055,637,2565,1148,367,766,1699,2965,772,1353,515,3006,2729,184,3301,39,1778,2495,2820,2762,1944,937,2416,14,409,1946,2457,2695
-0.6172178657741221,1.7702762612399765,0.22829128088385117,0.22829128088385117,0.060467414101225296,0.2005724364337766,-0.05350303097992167,-1.609172964600143,0.22829128088385117,1.4623297140439213,0.25591244186398043,-0.3160348969490162,1.0945945877969334,1.4382450552811312,-0.4053649182267038,-0.08226034641678645,-1.4765043166587404,0.25591244186398043,0.03213471430384632,-0.2276042406016599,-0.16915765752368028,0.7895593798784971,0.2005724364337766,-2.326814670181662,0.22829128088385117,-0.16915765752368028,2.3382725296462423,-1.1829292935550804,-0.2276042406016599,0.36544472945786843,0.9433672737733582,-0.2569802644281954,-0.43533889653030694,-0.8964011979097756,0.08869434652356714,0.44662661518260455,-0.1983298434546702,-0.14008827619228245,1.1692883875750077,-0.74037215539053,-1.5095468498520557,-0.34571237893882045,-0.3160348969490162,-0.5258453497283577,0.41965586752605055,0.17275463656922826,0.8923926409127418,-0.2276042406016599,3.356198648789754,-0.05350303097992167,-0.14008827619228245,-0.024850986633067236,0.08869434652356714,1.4141012478824513,-0.08226034641678645,0.31086666228014365,0.22829128088385117,2.092004590409298,-0.43533889653030694,1.24339256161293,2.514056875953885,-0.49557962951464074,0.11681693759758847,0.08869434652356714,2.5792918852390194,-0.34571237893882045,0.47350891704813686,0.08869434652356714,0.9687467516697891,1.0444625558272569,-0.7094431280794159,-0.34571237893882045,-3.3724914761196585,-1.2800184510915182,-1.9465598176439003,1.4382450552811312,-0.2569802644281954,-0.2276042406016599,0.41965586752605055,0.060467414101225296,0.03213471430384632,0.36544472945786843,-0.28645733903368353,1.0192936815049485,-0.5562072945734238,0.7895593798784971,-0.024850986633067236,3.1509596999717213,-0.1983298434546702,0.22829128088385117,-0.4053649182267038,0.31086666228014365,0.47350891704813686,-0.6786074245996516,-0.34571237893882045,0.08869434652356714,-1.2800184510915182,0.03213471430384632,1.7235018312297918,0.47350891704813686,-0.6172178657741221,1.8863015470497642,-1.0228587054425817,4.337756409373861,4.432259380667763,0.31086666228014365,-0.6172178657741221,-0.024850986633067236,0.17275463656922826,0.7636623002448963,0.060467414101225296,0.060467414101225296,0.7636623002448963,0.03213471430384632,0.7636623002448963,-0.2569802644281954,-1.3778800978198302,0.22829128088385117,-0.8650123589926522,0.47350891704813686,-0.11112230190969725,-0.1983298434546702,0.6330026427578571,0.33820212925301407,-1.0228587054425817,0.6066297150102449,-0.49557962951464074,0.25591244186398043,0.9433672737733582,0.5003038219140473,-0.024850986633067236,-0.8964011979097756,0.5003038219140473,0.14483658048926837,0.7376880792986121,-0.9594503693142111,-0.6172178657741221,1.5103236781354623,-1.9465598176439003,2.9423357816117885,-0.05350303097992167,-0.43533889653030694,-0.7094431280794159,-0.6478655125716591,-0.14008827619228245,0.39259560337501387,-0.3754892338100565,3.737500508749279,0.8923926409127418,-0.14008827619228245,-0.4053649182267038,-0.5866649642761562
3,375
er
17
85
2.89076
0.003843
P48449,O15173,Q969Q5,Q8N4V1,P48651,Q14739,O60499,Q9P2W9,Q15392,Q96GC9,Q13190,Q07065,P84085,Q06136,Q16850,P46977,Q99640
Localization
OpenCell Localization
opencell_localization
32,195,43,11,141,174,16,150,51,84,296,434,433,280,186,341,95
1157,2617,1162,1361,195,1164,2987,2907,16,710,2967,2542,2371,1316,555,1536,2101,2913,2422,1796,1491,2662,1599,341,32,141,2044,2708,1602,2220,2327,1735,2511,2512,952,2282,433,687,2671,280,434,296,174,3043,1288,2389,51,1335,2127,186,1676,1919,1747,3152,1921,962,11,2442,508,573,1298,2846,43,1463,1464,84,453,95,2067,3026,3055,1689,1518,1936,3319,1886,1771,1215,1701,2144,150,3109,1101,741,938
0.22829128088385117,-0.5562072945734238,0.22829128088385117,0.11681693759758847,1.4382450552811312,0.22829128088385117,-0.9594503693142111,-0.8337145938116572,3.697871107665648,0.5270123572912739,-0.9278806773204062,-0.49557962951464074,-0.3754892338100565,0.14483658048926837,0.6592940398904245,0.03213471430384632,-0.2276042406016599,-0.8337145938116572,-0.4053649182267038,-0.08226034641678645,0.060467414101225296,-0.5866649642761562,0.0036951455715587326,0.9940553151106681,3.130252972308468,1.7235018312297918,-0.1983298434546702,-0.6172178657741221,0.0036951455715587326,-0.28645733903368353,-0.34571237893882045,-0.05350303097992167,-0.4654106405661174,-0.4654106405661174,0.36544472945786843,-0.3160348969490162,0.8411254163810149,0.5536355300185024,-0.5866649642761562,1.1195590959099642,0.8411254163810149,1.0695626309218393,1.5342340098871912,-1.0228587054425817,0.17275463656922826,-0.3754892338100565,2.6009562194312528,0.14483658048926837,-0.2276042406016599,1.486355749287792,-0.024850986633067236,-0.14008827619228245,-0.05350303097992167,-1.2475690670035406,-0.14008827619228245,0.36544472945786843,3.9339465846713644,-0.4053649182267038,0.7376880792986121,0.6592940398904245,0.17275463656922826,-0.74037215539053,2.857891489435327,0.08869434652356714,0.08869434652356714,2.249349781196953,0.8153801473078209,2.159713234494772,-0.1983298434546702,-0.9911098512078583,-1.0228587054425817,-0.024850986633067236,0.060467414101225296,-0.14008827619228245,-2.1874571096956763,-0.11112230190969725,-0.05350303097992167,0.22829128088385117,-0.024850986633067236,-0.2276042406016599,1.700034827064007,-1.150739668468142,0.28343716336325137,0.5270123572912739,0.39259560337501387
3,375
Glycerolipid biosynthetic process
7
45
2.870713
0.004095
Q9NPH0,Q8WTV0,Q8NCC3,P35790,P48651,Q9C0D9,Q9BYI3
Processes and pathways
GO Biological process
msigdb_gobp
35,6,7,13,141,109,86
1220,1162,1163,1953,983,2212,3257,988,13,141,1669,414,918,1980,315,2130,7,1996,508,6,2959,1571,1619,2870,2720,1462,2005,453,3127,2562,1687,2244,2564,3026,2299,86,109,1148,172,35,1215,1255,551,740,854
0.2005724364337766,0.22829128088385117,0.22829128088385117,-0.16915765752368028,0.33820212925301407,-0.28645733903368353,-1.609172964600143,0.33820212925301407,3.7572720143403053,1.7235018312297918,-0.024850986633067236,0.8667959860819097,0.39259560337501387,-0.16915765752368028,1.0444625558272569,-0.2276042406016599,4.337756409373861,-0.16915765752368028,0.7376880792986121,4.432259380667763,-0.8964011979097756,0.03213471430384632,0.0036951455715587326,-0.771394044942476,-0.6172178657741221,0.08869434652356714,-0.16915765752368028,0.8153801473078209,-1.1829292935550804,-0.49557962951464074,-0.024850986633067236,-0.28645733903368353,-0.49557962951464074,-0.9911098512078583,-0.3160348969490162,2.2270083787382036,2.0238730257815676,0.25591244186398043,1.5580872461878,3.0887372059217104,0.22829128088385117,0.2005724364337766,0.6855048182603979,0.5270123572912739,0.44662661518260455
3,375
Aganglionic megacolon
10
19
2.868921
0.004119
Q9BXW9,Q10713,Q9UJX6,O15360,Q96EK5,Q92890,P42892,Q8WXW3,Q9UBM7,Q92766
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
292,414,305,477,574,439,50,318,57,382
940,477,907,2217,1600,50,1379,414,1192,1240,318,382,439,574,292,637,1014,57,305
0.36544472945786843,0.7636623002448963,0.39259560337501387,-0.28645733903368353,0.0036951455715587326,2.622580671152067,0.11681693759758847,0.8667959860819097,0.22829128088385117,0.2005724364337766,1.0444625558272569,0.91791615126421,0.8411254163810149,0.6592940398904245,1.0945945877969334,0.6066297150102449,0.33820212925301407,2.5792918852390194,1.0695626309218393
3,375
Steroid biosynthesis
6
22
2.868087
0.00413
P48449,Q14739,Q15392,Q9UBM7,Q16850,Q9H3P7
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
32,174,51,57,186,60
1536,253,2315,412,32,2510,2940,1038,1916,174,2126,51,1335,2635,186,959,1395,2898,2298,60,57,1841
0.03213471430384632,1.2187556408509548,-0.34571237893882045,0.8667959860819097,3.130252972308468,-0.4654106405661174,-0.8650123589926522,0.31086666228014365,-0.14008827619228245,1.5342340098871912,-0.2276042406016599,2.6009562194312528,0.14483658048926837,-0.5562072945734238,1.486355749287792,0.36544472945786843,0.11681693759758847,-0.8025083410499405,-0.3160348969490162,2.5358424878703127,2.5792918852390194,-0.08226034641678645
3,375
Inorganic anion transport
12
25
2.862712
0.0042
Q8TDW0,Q6N075,Q9C0H2,Q9UBX3,Q4KMQ2,Q9UHG3,P08183,P21796,P51798,Q9Y277,P0CG08,P45880
Processes and pathways
GO Biological process
msigdb_gobp
530,361,80,144,360,113,53,24,180,552,340,62
898,1709,683,53,340,24,1176,62,180,2168,598,1280,360,361,530,3222,80,2565,1310,144,113,552,2904,776,1586
0.39259560337501387,-0.05350303097992167,0.5536355300185024,2.5792918852390194,0.9940553151106681,3.356198648789754,0.22829128088385117,2.514056875953885,1.5103236781354623,-0.2569802644281954,0.6330026427578571,0.17275463656922826,0.9433672737733582,0.9433672737733582,0.7116358722612617,-1.4435454454021128,2.2716465763795988,-0.49557962951464074,0.17275463656922826,1.7235018312297918,2.0010668397853175,0.6855048182603979,-0.8025083410499405,0.5003038219140473,0.03213471430384632
3,375
Sterol metabolic process
13
38
2.856697
0.004281
P48449,Q8WTV0,O15118,P35610,Q9H2C2,P37268,P05067,Q14739,P04062,Q15392,Q9UBM7,Q16850,P04035
Processes and pathways
GO Biological process
msigdb_gobp
32,6,285,102,404,412,166,174,358,51,57,186,253
285,1954,3112,1536,253,358,166,1657,2315,1540,2737,102,412,3264,1177,32,448,1180,2510,3298,2175,2940,1038,1916,724,174,1190,1039,2126,51,1335,2635,186,6,404,57,2950,1841
1.0945945877969334,-0.16915765752368028,-1.1829292935550804,0.03213471430384632,1.2187556408509548,0.9433672737733582,1.5580872461878,-0.024850986633067236,-0.34571237893882045,0.03213471430384632,-0.6478655125716591,2.092004590409298,0.8667959860819097,-1.6425467075224687,0.22829128088385117,3.130252972308468,0.8153801473078209,0.22829128088385117,-0.4654106405661174,-1.9465598176439003,-0.2569802644281954,-0.8650123589926522,0.31086666228014365,-0.14008827619228245,0.5270123572912739,1.5342340098871912,0.22829128088385117,0.31086666228014365,-0.2276042406016599,2.6009562194312528,0.14483658048926837,-0.5562072945734238,1.486355749287792,4.432259380667763,0.8923926409127418,2.5792918852390194,-0.8650123589926522,-0.08226034641678645
3,375
Lipid droplet
10
35
2.842442
0.004477
P48449,P09455,Q99720,Q9H6V9,O43760,Q07065,Q8TCD1,Q8NBX0,Q96RL7,Q96BY7
Localization
GO Cellular component
msigdb_gocc
32,267,12,48,270,434,118,120,58,487
1222,270,1478,2934,983,1536,2266,2953,267,32,2427,2801,2220,2327,911,1330,434,2556,1335,1394,1395,120,508,118,1049,487,1928,58,12,703,48,1936,3173,2082,1645
0.2005724364337766,1.144456813443884,0.060467414101225296,-0.8650123589926522,0.33820212925301407,0.03213471430384632,-0.3160348969490162,-0.8964011979097756,1.1692883875750077,3.130252972308468,-0.4053649182267038,-0.7094431280794159,-0.28645733903368353,-0.34571237893882045,0.39259560337501387,0.14483658048926837,0.8411254163810149,-0.49557962951464074,0.14483658048926837,0.11681693759758847,0.11681693759758847,1.9093538048745637,0.7376880792986121,1.9782122047843376,0.31086666228014365,0.7636623002448963,-0.14008827619228245,2.557587398973077,3.9144271277439557,0.5536355300185024,2.6441655068947094,-0.14008827619228245,-1.2800184510915182,-0.1983298434546702,0.0036951455715587326
3,375
Metalloprotease
10
27
2.830796
0.004643
Q9NZ08,Q9UIQ6,Q9BYT8,P42892,Q7Z2K6,P55786,O75844,Q5JRX3,O75976,O95630
Functions
Protein Atlas Molecular function
protein_atlas_molecular_function
204,100,402,50,116,22,88,281,587,589
2022,615,1787,88,587,589,2269,1895,1539,50,950,22,281,3234,116,1460,1138,1930,2136,402,1305,1937,812,1152,204,100,2018
-0.1983298434546702,0.6066297150102449,-0.08226034641678645,2.2046220417723954,0.6330026427578571,0.6330026427578571,-0.3160348969490162,-0.14008827619228245,0.03213471430384632,2.622580671152067,0.36544472945786843,3.4171394805890736,1.1195590959099642,-1.4765043166587404,1.9782122047843376,0.08869434652356714,0.25591244186398043,-0.14008827619228245,-0.2276042406016599,0.8923926409127418,0.17275463656922826,-0.14008827619228245,0.47350891704813686,0.25591244186398043,1.4382450552811312,2.1146206568398127,-0.16915765752368028
3,375
Organic anion transport
20
53
2.826238
0.00471
Q86VD7,Q8TDW0,Q9UBX3,P28288,Q9H2J7,P11166,P53007,P12236,P53985,P12235,Q9HC21,Q7L0J3,Q9Y619,Q9H2D1,P30825,Q14728,Q9BQT8,Q9NZJ7,O95563,P14174
Processes and pathways
GO Biological process
msigdb_gobp
133,530,144,653,546,651,162,541,657,54,192,69,475,81,85,355,490,772,616,255
2539,2657,1709,1314,1416,1847,2542,616,2156,865,2734,1420,2373,651,54,541,255,653,85,1430,162,657,2168,1280,3066,1038,355,1288,2556,2557,1291,1614,1747,69,133,762,530,1760,490,81,546,930,1884,192,2965,772,144,1841,2205,2904,1946,475,1586
-0.49557962951464074,-0.5866649642761562,-0.05350303097992167,0.14483658048926837,0.08869434652356714,-0.11112230190969725,-0.49557962951464074,0.6066297150102449,-0.2569802644281954,0.41965586752605055,-0.6478655125716591,0.08869434652356714,-0.3754892338100565,0.5801743268480191,2.5792918852390194,0.6855048182603979,1.2187556408509548,0.5801743268480191,2.2270083787382036,0.08869434652356714,1.5818838811891258,0.5801743268480191,-0.2569802644281954,0.17275463656922826,-1.0546965194844964,0.31086666228014365,0.9687467516697891,0.17275463656922826,-0.49557962951464074,-0.49557962951464074,0.17275463656922826,0.0036951455715587326,-0.05350303097992167,2.4484530262047968,1.8168408195595176,0.5003038219140473,0.7116358722612617,-0.05350303097992167,0.7636623002448963,2.2716465763795988,0.6855048182603979,0.39259560337501387,-0.11112230190969725,1.4623297140439213,-0.8964011979097756,0.5003038219140473,1.7235018312297918,-0.08226034641678645,-0.2569802644281954,-0.8025083410499405,-0.14008827619228245,0.7895593798784971,0.03213471430384632
3,375
Vacuole organization
18
57
2.815167
0.004875
Q9H2M9,P11117,O14773,O75503,P53365,Q9HC07,Q6UWE0,Q9Y4P8,P10253,P04062,Q8N511,Q96GC9,Q12768,P50897,Q96ED9,Q96BY7,Q9P253,Q14108
Processes and pathways
GO Biological process
msigdb_gobp
493,286,188,98,353,302,169,409,231,358,178,84,181,55,121,487,457,31
858,188,2967,98,1848,1956,2098,358,2953,3218,231,286,1064,2990,1034,791,55,2801,353,480,1736,1738,2381,181,31,918,2556,2337,2520,169,3202,1821,178,2846,730,487,121,84,842,2010,1145,1146,493,302,1254,2949,457,1471,1355,1777,2820,2569,2762,1944,937,2017,409
0.41965586752605055,1.4623297140439213,-0.9278806773204062,2.1146206568398127,-0.11112230190969725,-0.16915765752368028,-0.2276042406016599,0.9433672737733582,-0.8964011979097756,-1.4435454454021128,1.292476019958997,1.0945945877969334,0.28343716336325137,-0.9594503693142111,0.31086666228014365,0.47350891704813686,2.5792918852390194,-0.7094431280794159,0.9687467516697891,0.7636623002448963,-0.05350303097992167,-0.05350303097992167,-0.3754892338100565,1.5103236781354623,3.1509596999717213,0.39259560337501387,-0.49557962951464074,-0.34571237893882045,-0.4654106405661174,1.5580872461878,-1.3778800978198302,-0.08226034641678645,1.5342340098871912,-0.74037215539053,0.5270123572912739,0.7636623002448963,1.9093538048745637,2.249349781196953,0.44662661518260455,-0.16915765752368028,0.25591244186398043,0.25591244186398043,0.7636623002448963,1.0695626309218393,0.2005724364337766,-0.8650123589926522,0.8153801473078209,0.08869434652356714,0.14483658048926837,-0.05350303097992167,-0.7094431280794159,-0.49557962951464074,-0.6478655125716591,-0.14008827619228245,0.39259560337501387,-0.16915765752368028,0.8923926409127418
3,375
Endopeptidase activity
17
60
2.80492
0.005033
P28072,P67812,Q96K76,O14773,Q16740,Q9NZ08,Q10713,P07384,P28070,Q9BYT8,P42892,P20618,O75844,Q5JRX3,Q99538,P49721,Q4J6C6
Functions
GO Molecular function
msigdb_gomf
129,34,290,188,417,204,414,123,205,402,50,147,88,281,92,59,191
188,3367,615,1787,88,123,2829,1539,3257,147,1174,1426,205,129,557,1322,2586,2624,948,50,1727,874,686,59,2473,950,1380,597,34,414,2180,2435,1189,417,191,281,1746,3234,1132,1455,2446,2720,1460,452,1461,290,1831,1930,672,92,2136,1209,1053,402,204,2610,1017,1018,2017,2018
1.4623297140439213,-4.204814994147441,0.6066297150102449,-0.08226034641678645,2.2046220417723954,1.8863015470497642,-0.74037215539053,0.03213471430384632,-1.609172964600143,1.700034827064007,0.22829128088385117,0.08869434652356714,1.4141012478824513,1.8400454612708395,0.6592940398904245,0.14483658048926837,-0.5258453497283577,-0.5562072945734238,0.36544472945786843,2.622580671152067,-0.05350303097992167,0.41965586752605055,0.5536355300185024,2.5358424878703127,-0.43533889653030694,0.36544472945786843,0.11681693759758847,0.6330026427578571,3.0887372059217104,0.8667959860819097,-0.2569802644281954,-0.4053649182267038,0.22829128088385117,0.8667959860819097,1.4623297140439213,1.1195590959099642,-0.05350303097992167,-1.4765043166587404,0.25591244186398043,0.08869434652356714,-0.4053649182267038,-0.6172178657741221,0.08869434652356714,0.8153801473078209,0.08869434652356714,1.0945945877969334,-0.08226034641678645,-0.14008827619228245,0.5801743268480191,2.182190438903513,-0.2276042406016599,0.22829128088385117,0.31086666228014365,0.8923926409127418,1.4382450552811312,-0.5258453497283577,0.33820212925301407,0.33820212925301407,-0.16915765752368028,-0.16915765752368028
3,375
Regulation of cellular ph
9
21
2.790721
0.005259
O75503,Q92544,P61421,Q9HC07,Q9UI12,Q8N511,P50897,Q93050,P0CG08
Processes and pathways
GO Biological process
msigdb_gobp
98,356,287,302,235,178,55,155,340
98,1848,3134,340,1799,2379,55,2801,287,915,1336,178,356,155,730,302,369,235,741,776,1586
2.1146206568398127,-0.11112230190969725,-1.2152058878452634,0.9940553151106681,-0.08226034641678645,-0.3754892338100565,2.5792918852390194,-0.7094431280794159,1.0945945877969334,0.39259560337501387,0.14483658048926837,1.5342340098871912,0.9687467516697891,1.6529390108089894,0.5270123572912739,1.0695626309218393,0.9433672737733582,1.292476019958997,0.5270123572912739,0.5003038219140473,0.03213471430384632
3,375
Regulation of ph
9
21
2.790721
0.005259
O75503,Q92544,P61421,Q9HC07,Q9UI12,Q8N511,P50897,Q93050,P0CG08
Processes and pathways
GO Biological process
msigdb_gobp
98,356,287,302,235,178,55,155,340
98,1848,3134,340,1799,2379,55,2801,287,915,1336,178,356,155,730,302,369,235,741,776,1586
2.1146206568398127,-0.11112230190969725,-1.2152058878452634,0.9940553151106681,-0.08226034641678645,-0.3754892338100565,2.5792918852390194,-0.7094431280794159,1.0945945877969334,0.39259560337501387,0.14483658048926837,1.5342340098871912,0.9687467516697891,1.6529390108089894,0.5270123572912739,1.0695626309218393,0.9433672737733582,1.292476019958997,0.5270123572912739,0.5003038219140473,0.03213471430384632
3,375
Alzheimers disease and mirna effects
25
88
2.762729
0.005732
P28072,Q9Y4P8,Q99436,P31751,P20618,P21796,Q9Y277,P49841,Q16186,P12236,Q9UJX6,P05067,P12235,P49720,P49721,P45880,P28074,P28070,Q96GC9,Q00535,P60900,Q96BY7,O95197,Q08209,P07384
Processes and pathways
WikiPathways
msigdb_wp
129,409,672,148,147,24,552,157,662,541,305,166,54,686,59,62,557,205,84,599,597,487,588,483,123
2258,2366,2022,2088,2789,1165,588,2266,166,865,2029,123,1026,3227,54,541,1539,1064,3257,2583,2584,1489,715,147,24,1425,786,1227,1426,1799,2795,205,129,557,2379,1545,148,1547,1903,2769,1801,1034,948,2276,62,992,827,875,686,59,157,1552,2326,597,2742,2222,1604,1740,1072,599,1741,1186,483,2178,1498,1331,2891,997,918,1076,662,1823,2446,487,84,2757,672,1686,1687,3052,1763,1143,2450,1886,305,2414,552,409
-0.3160348969490162,-0.3754892338100565,-0.1983298434546702,-0.2276042406016599,-0.7094431280794159,0.22829128088385117,0.6330026427578571,-0.3160348969490162,1.5580872461878,0.41965586752605055,-0.1983298434546702,1.8863015470497642,0.31086666228014365,-1.4765043166587404,2.5792918852390194,0.6855048182603979,0.03213471430384632,0.28343716336325137,-1.609172964600143,-0.5258453497283577,-0.5258453497283577,0.060467414101225296,0.5270123572912739,1.700034827064007,3.356198648789754,0.08869434652356714,0.47350891704813686,0.2005724364337766,0.08869434652356714,-0.08226034641678645,-0.7094431280794159,1.4141012478824513,1.8400454612708395,0.6592940398904245,-0.3754892338100565,0.03213471430384632,1.700034827064007,0.03213471430384632,-0.14008827619228245,-0.6786074245996516,-0.08226034641678645,0.31086666228014365,0.36544472945786843,-0.3160348969490162,2.514056875953885,0.33820212925301407,0.44662661518260455,0.41965586752605055,0.5536355300185024,2.5358424878703127,1.6293092873800175,0.03213471430384632,-0.34571237893882045,0.6330026427578571,-0.6478655125716591,-0.28645733903368353,0.0036951455715587326,-0.05350303097992167,0.28343716336325137,0.6330026427578571,-0.05350303097992167,0.22829128088385117,0.7636623002448963,-0.2569802644281954,0.060467414101225296,0.14483658048926837,-0.8025083410499405,0.33820212925301407,0.39259560337501387,0.28343716336325137,0.5801743268480191,-0.08226034641678645,-0.4053649182267038,0.7636623002448963,2.249349781196953,-0.6478655125716591,0.5801743268480191,-0.024850986633067236,-0.024850986633067236,-1.0228587054425817,-0.05350303097992167,0.25591244186398043,-0.4053649182267038,-0.11112230190969725,1.0695626309218393,-0.3754892338100565,0.6855048182603979,0.8923926409127418
3,375
Duplication involving bones of the feet
10
22
2.757368
0.005827
O96028,Q9Y263,Q8NCM8,Q10713,Q14739,Q92890,Q8WXW3,Q9UBM7,Q7Z4L5,Q92766
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
65,338,379,414,174,439,318,57,570,382
940,1368,2027,65,907,2217,1379,414,1815,174,1240,570,379,318,382,439,2527,637,2687,57,1355,338
0.36544472945786843,0.11681693759758847,-0.1983298434546702,2.4922302839791723,0.39259560337501387,-0.28645733903368353,0.11681693759758847,0.8667959860819097,-0.08226034641678645,1.5342340098871912,0.2005724364337766,0.6592940398904245,0.91791615126421,1.0444625558272569,0.91791615126421,0.8411254163810149,-0.4654106405661174,0.6066297150102449,-0.5866649642761562,2.5792918852390194,0.14483658048926837,1.0192936815049485
3,375
Steroid metabolic process
16
68
2.746761
0.006019
P48449,Q8WTV0,O15118,P35610,Q9H2C2,P37268,P05067,Q99538,Q14739,P04062,Q15392,Q9UBM7,P38435,Q16850,Q9H3P7,P04035
Processes and pathways
GO Biological process
msigdb_gobp
32,6,285,102,404,412,166,92,174,358,51,57,245,186,60,253
1648,285,1954,3112,1316,1536,253,358,2461,166,2580,1657,2315,2831,1540,715,1718,1898,2737,2377,653,1176,102,412,245,3264,1177,32,448,2919,2167,1180,2510,3298,2175,2940,1912,1038,2890,1916,724,174,1190,1039,2126,51,1445,1335,2635,186,959,2520,1395,6,2898,926,1575,92,3052,1304,2298,404,60,57,2950,933,1841,1311
-0.024850986633067236,1.0945945877969334,-0.16915765752368028,-1.1829292935550804,0.14483658048926837,0.03213471430384632,1.2187556408509548,0.9433672737733582,-0.43533889653030694,1.5580872461878,-0.5258453497283577,-0.024850986633067236,-0.34571237893882045,-0.74037215539053,0.03213471430384632,0.5270123572912739,-0.05350303097992167,-0.14008827619228245,-0.6478655125716591,-0.3754892338100565,0.5801743268480191,0.22829128088385117,2.092004590409298,0.8667959860819097,1.24339256161293,-1.6425467075224687,0.22829128088385117,3.130252972308468,0.8153801473078209,-0.8337145938116572,-0.2569802644281954,0.22829128088385117,-0.4654106405661174,-1.9465598176439003,-0.2569802644281954,-0.8650123589926522,-0.14008827619228245,0.31086666228014365,-0.8025083410499405,-0.14008827619228245,0.5270123572912739,1.5342340098871912,0.22829128088385117,0.31086666228014365,-0.2276042406016599,2.6009562194312528,0.08869434652356714,0.14483658048926837,-0.5562072945734238,1.486355749287792,0.36544472945786843,-0.4654106405661174,0.11681693759758847,4.432259380667763,-0.8025083410499405,0.39259560337501387,0.03213471430384632,2.182190438903513,-1.0228587054425817,0.17275463656922826,-0.3160348969490162,0.8923926409127418,2.5358424878703127,2.5792918852390194,-0.8650123589926522,0.39259560337501387,-0.08226034641678645,0.17275463656922826
3,375
Lysosomal lumen
16
35
2.740015
0.006144
P11117,O14773,Q8NHP8,Q9UM22,P04066,P10253,P10619,P16278,P04062,P06280,P50897,P38435,Q9UMR5,Q99538,Q8IV08,Q14108
Localization
GO Cellular component
msigdb_gocc
286,188,99,39,266,231,196,207,358,432,55,245,122,92,94,31
975,3187,188,683,358,266,432,684,1420,3218,2267,650,231,196,286,2314,2856,207,2034,245,3264,1493,55,480,3298,2890,31,94,2944,99,92,732,772,39,122
0.33820212925301407,-1.3451743358044173,1.4623297140439213,0.5536355300185024,0.9433672737733582,1.1692883875750077,0.8411254163810149,0.5536355300185024,0.08869434652356714,-1.4435454454021128,-0.3160348969490162,0.5801743268480191,1.292476019958997,1.4382450552811312,1.0945945877969334,-0.34571237893882045,-0.771394044942476,1.3898977585599475,-0.1983298434546702,1.24339256161293,-1.6425467075224687,0.060467414101225296,2.5792918852390194,0.7636623002448963,-1.9465598176439003,-0.8025083410499405,3.1509596999717213,2.159713234494772,-0.8650123589926522,2.1146206568398127,2.182190438903513,0.5270123572912739,0.5003038219140473,2.9423357816117885,1.9093538048745637
3,375
Protein transport
71
278
2.737926
0.006183
O60830,Q9H9H4,Q9BUN8,Q2M389,Q13505,Q92621,A6NIH7,O15397,Q9UIA9,O60499,O00410,Q9P2W9,P50542,O43933,P20337,Q15629,Q99595,Q9NRW7,Q9NS69,Q9HCU5,Q5VZ89,O14925,Q15388,Q6UWE0,Q99442,Q969Q5,Q15436,Q15833,Q6WKZ4,Q12768,P84085,Q96RL7,Q9P253,P41208,Q9HAV4,Q5JVF3,Q12769,O15126,Q13432,Q8TEX9,Q9HD20,O75351,Q9NP79,O60784,Q96D46,Q9HD26,O95070,Q9C0E2,Q96MW5,Q8N5M9,O94832,P0CG08,P42566,Q7Z3U7,P53621,Q96T51,Q9BTX1,Q9UI26,Q96L92,Q9H4A6,O43823,Q9H0F7,Q03518,Q8N4H5,Q9Y678,Q9UJY4,Q15276,P49257,Q96ED9,A0AVF1,Q8N3F8
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
0,673,533,132,8,668,138,265,406,16,518,150,522,145,271,154,28,549,29,547,421,284,288,169,577,43,436,175,569,181,433,58,457,310,455,565,562,443,331,605,209,323,611,460,347,610,461,218,247,225,339,340,351,465,595,489,234,370,488,367,230,637,111,485,517,515,119,621,121,250,124
250,974,138,897,2021,1947,858,518,2260,1476,1949,645,1360,1259,284,1104,1105,820,443,3368,265,1651,2263,1222,2370,3225,1710,1590,2023,230,145,2092,16,3356,646,2150,1952,1845,460,2576,0,1416,1534,323,2967,2732,1654,2026,2912,339,2096,982,461,1112,1024,1535,1959,1062,3060,1714,1264,340,1854,1796,2857,271,1961,2990,3036,1325,2163,2217,2467,310,351,2471,1864,621,1729,2044,2509,1432,522,2427,2801,2708,1602,2220,2771,793,719,1966,1967,595,2772,1379,1733,876,1908,1734,1735,1736,2329,2512,2280,952,1738,1383,2862,3136,913,2223,2381,1554,2382,1121,1866,433,111,2514,2178,1073,181,562,2286,331,8,1673,1334,1039,119,2337,2389,288,436,3210,154,175,2482,132,881,3271,3334,3201,2234,565,758,2924,421,1290,1985,169,569,2805,465,3202,1821,803,2751,1296,2718,1509,124,485,225,3051,2397,2683,1997,1202,1340,1084,2719,605,1825,1003,1617,2846,2241,1049,668,1683,1398,43,730,3251,1512,347,3272,121,669,3310,1008,488,247,1009,842,58,489,577,2563,2194,28,2357,2810,1140,234,533,2813,2782,1883,2532,1466,218,637,1145,2012,1146,367,703,1693,2071,2246,673,455,547,209,610,2849,1936,611,1771,1403,549,29,1254,1699,2949,1887,851,770,771,3156,457,2875,150,1582,773,2615,1775,370,406,1703,515,3006,2787,2494,1355,1100,1777,2495,2692,1639,2569,2364,1405,3031,1258,1101,1944,2017,2085,2788,818,3111,2457,2695,517
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3,375
Inorganic molecular entity transmembrane transporter activity
28
78
2.719273
0.006543
Q8TDW0,Q8N4V1,Q9UBX3,O75964,P21796,Q9Y277,Q93050,P00846,Q6P4Q7,Q9H2J7,P61421,P00403,Q9HC07,Q13423,P51798,P12235,P45880,P56134,P21281,Q9C0H2,Q9HD20,Q9UDW1,Q00535,Q00325,P0CG08,Q9UI12,Q6N075,Q4KMQ2
Functions
GO Molecular function
msigdb_gomf
530,11,144,393,24,552,155,156,159,546,287,538,302,435,180,54,62,561,446,80,209,471,599,598,340,235,361,360
898,2697,1709,683,3146,393,2027,538,156,2461,2619,865,3134,2953,2031,2373,1063,340,2424,54,591,1064,1541,1797,446,1857,24,2109,3037,1033,3093,2916,2859,1428,62,3018,3135,180,2168,561,2474,287,1383,2383,598,599,1280,435,3046,360,361,159,1920,11,1823,530,1927,155,3222,2136,80,3140,546,930,302,209,675,1310,144,471,235,3109,552,2904,741,2694,776,1586
0.39259560337501387,-0.6172178657741221,-0.05350303097992167,0.5536355300185024,-1.2475690670035406,0.8923926409127418,-0.1983298434546702,0.6855048182603979,1.6293092873800175,-0.43533889653030694,-0.5562072945734238,0.41965586752605055,-1.2152058878452634,-0.8964011979097756,-0.1983298434546702,-0.3754892338100565,0.28343716336325137,0.9940553151106681,-0.4053649182267038,2.5792918852390194,0.6330026427578571,0.28343716336325137,0.03213471430384632,-0.08226034641678645,0.8153801473078209,-0.11112230190969725,3.356198648789754,-0.2276042406016599,-1.0228587054425817,0.31086666228014365,-1.1186374013991909,-0.8337145938116572,-0.771394044942476,0.08869434652356714,2.514056875953885,-0.9911098512078583,-1.2152058878452634,1.5103236781354623,-0.2569802644281954,0.6592940398904245,-0.43533889653030694,1.0945945877969334,0.11681693759758847,-0.3754892338100565,0.6330026427578571,0.6330026427578571,0.17275463656922826,0.8411254163810149,-1.0228587054425817,0.9433672737733582,0.9433672737733582,1.6056244017080097,-0.14008827619228245,3.9339465846713644,-0.08226034641678645,0.7116358722612617,-0.14008827619228245,1.6529390108089894,-1.4435454454021128,-0.2276042406016599,2.2716465763795988,-1.2152058878452634,0.6855048182603979,0.39259560337501387,1.0695626309218393,1.3898977585599475,0.5801743268480191,0.17275463656922826,1.7235018312297918,0.7895593798784971,1.292476019958997,-1.150739668468142,0.6855048182603979,-0.8025083410499405,0.5270123572912739,-0.5866649642761562,0.5003038219140473,0.03213471430384632
3,375
Vesicle membrane
57
273
2.715502
0.006618
P17931,Q8WTV0,O15260,P42785,Q8N4V1,P20645,O60499,Q7Z3T8,P20337,O43760,O00461,P12429,Q93050,Q14108,Q5VZ89,Q99805,P61421,O15118,Q9HC07,Q969Q5,P42858,P30519,Q9NQX7,Q15436,Q6P3W7,P42892,Q8N511,Q9UKG1,Q13190,Q07065,Q96RL7,Q9UH99,Q9P253,O15126,Q7L0J3,P63167,O75351,O60784,Q5KU26,Q13576,Q7Z3U7,Q8IV08,P42566,Q14728,Q9UIQ6,Q96T51,Q96L92,P10253,P27105,Q03518,Q4KMQ2,Q9Y678,Q9UJY4,Q15276,Q8N3F8,Q8NF37,Q13555
Localization
GO Cellular component
msigdb_gocc
256,6,9,10,11,137,16,143,271,270,278,394,155,31,421,36,287,285,302,43,167,41,44,436,297,50,178,184,296,434,58,458,457,443,69,197,323,460,344,463,465,94,351,355,100,489,488,231,479,111,360,517,515,119,124,508,505
1313,974,897,2021,858,1157,1158,2306,1475,278,1949,645,1259,2657,1104,820,285,1361,443,3368,9,2497,1709,1651,1166,3225,1590,2023,270,1108,3217,2092,16,1479,646,2934,1952,1845,460,1416,1224,1534,710,323,2967,1654,1848,822,2096,982,1959,1062,3060,1714,1113,2156,3105,2734,2953,1420,2031,2914,1320,2828,3227,231,1892,2314,2213,2105,869,394,2106,1792,256,1541,2107,271,1961,2990,3036,137,1719,479,3083,2586,41,2882,989,1325,3062,1599,351,10,167,50,1377,1864,621,2044,503,2427,2801,2708,1602,2771,1967,595,2772,1379,2168,2329,2280,952,1738,1232,287,2920,2862,3136,2223,2381,2330,1555,2382,197,687,1037,1669,111,434,3066,1073,2120,2284,1498,1557,296,2229,626,505,463,1673,31,2554,2892,918,2052,355,1190,1039,2775,119,2337,1563,2389,436,3210,2841,2482,1336,360,3271,344,1448,2679,2924,421,2520,1290,297,569,69,143,465,1821,803,1082,94,124,11,178,3051,2683,695,508,2349,6,2446,3169,1683,155,43,730,1512,670,3313,488,3127,842,58,1575,489,1516,1687,36,2810,1209,2947,1140,3373,1012,1053,1466,3054,2010,3140,2785,2012,1146,703,673,302,610,2849,1936,611,44,1771,549,2949,851,770,772,3156,2144,457,739,1353,853,1582,773,1839,458,1841,100,1637,515,3006,184,2494,1355,1942,1100,1777,1778,2495,3195,2569,2904,1584,3131,1405,1258,1944,741,2694,2457,2695,517,776,2257,743
0.14483658048926837,0.33820212925301407,0.39259560337501387,-0.1983298434546702,0.41965586752605055,0.22829128088385117,0.22829128088385117,-0.34571237893882045,0.060467414101225296,1.1195590959099642,-0.16915765752368028,0.5801743268480191,0.17275463656922826,-0.5866649642761562,0.25591244186398043,0.44662661518260455,1.0945945877969334,0.11681693759758847,0.8153801473078209,-4.320785578494506,4.069826366870343,-0.4654106405661174,-0.05350303097992167,-0.024850986633067236,0.22829128088385117,-1.4765043166587404,0.0036951455715587326,-0.1983298434546702,1.144456813443884,0.25591244186398043,-1.4435454454021128,-0.2276042406016599,3.697871107665648,0.060467414101225296,0.5801743268480191,-0.8650123589926522,-0.16915765752368028,-0.11112230190969725,0.7895593798784971,0.08869434652356714,0.2005724364337766,0.03213471430384632,0.5270123572912739,1.0192936815049485,-0.9278806773204062,-0.024850986633067236,-0.11112230190969725,0.44662661518260455,-0.2276042406016599,0.33820212925301407,-0.16915765752368028,0.28343716336325137,-1.0546965194844964,-0.05350303097992167,0.25591244186398043,-0.2569802644281954,-1.150739668468142,-0.6478655125716591,-0.8964011979097756,0.08869434652356714,-0.1983298434546702,-0.8337145938116572,0.14483658048926837,-0.74037215539053,-1.4765043166587404,1.292476019958997,-0.14008827619228245,-0.34571237893882045,-0.28645733903368353,-0.2276042406016599,0.41965586752605055,0.8923926409127418,-0.2276042406016599,-0.08226034641678645,1.2187556408509548,0.03213471430384632,-0.2276042406016599,1.144456813443884,-0.16915765752368028,-0.9594503693142111,-1.0228587054425817,1.7935845599756126,-0.05350303097992167,0.7636623002448963,-1.0866228857275761,-0.5258453497283577,2.857891489435327,-0.8025083410499405,0.33820212925301407,0.14483658048926837,-1.0546965194844964,0.0036951455715587326,0.9687467516697891,4.011752901252815,1.5580872461878,2.622580671152067,0.11681693759758847,-0.11112230190969725,0.6066297150102449,-0.1983298434546702,0.7376880792986121,-0.4053649182267038,-0.7094431280794159,-0.6172178657741221,0.0036951455715587326,-0.6786074245996516,-0.16915765752368028,0.6330026427578571,-0.6786074245996516,0.11681693759758847,-0.2569802644281954,-0.34571237893882045,-0.3160348969490162,0.36544472945786843,-0.05350303097992167,0.2005724364337766,1.0945945877969334,-0.8337145938116572,-0.771394044942476,-1.2152058878452634,-0.28645733903368353,-0.3754892338100565,-0.34571237893882045,0.03213471430384632,-0.3754892338100565,1.4382450552811312,0.5536355300185024,0.31086666228014365,-0.024850986633067236,2.0010668397853175,0.8411254163810149,-1.0546965194844964,0.28343716336325137,-0.2276042406016599,-0.3160348969490162,0.060467414101225296,0.03213471430384632,1.0695626309218393,-0.28645733903368353,0.6066297150102449,0.7376880792986121,0.7895593798784971,-0.024850986633067236,3.1509596999717213,-0.49557962951464074,-0.8025083410499405,0.39259560337501387,-0.1983298434546702,0.9687467516697891,0.22829128088385117,0.31086666228014365,-0.6786074245996516,1.9553087432535796,-0.34571237893882045,0.03213471430384632,-0.3754892338100565,0.8411254163810149,-1.4106705873943675,-0.74037215539053,-0.43533889653030694,0.14483658048926837,0.9433672737733582,-1.6760024115861647,0.9940553151106681,0.08869434652356714,-0.5866649642761562,-0.8337145938116572,0.8667959860819097,-0.4654106405661174,0.17275463656922826,1.0695626309218393,0.6592940398904245,2.4484530262047968,1.7235018312297918,0.7895593798784971,-0.08226034641678645,0.47350891704813686,0.28343716336325137,2.159713234494772,1.8863015470497642,3.9339465846713644,1.5342340098871912,-1.0228587054425817,-0.5866649642761562,0.5536355300185024,0.7376880792986121,-0.34571237893882045,4.432259380667763,-0.4053649182267038,-1.2800184510915182,-0.024850986633067236,1.6529390108089894,2.857891489435327,0.5270123572912739,0.060467414101225296,0.5801743268480191,-2.1182396459777886,0.7636623002448963,-1.1829292935550804,0.44662661518260455,2.557587398973077,0.03213471430384632,0.7636623002448963,0.060467414101225296,-0.024850986633067236,3.0262046723466742,-0.7094431280794159,0.22829128088385117,-0.8650123589926522,0.25591244186398043,-10.357023878767876,0.33820212925301407,0.31086666228014365,0.08869434652356714,-1.0228587054425817,-0.16915765752368028,-1.2152058878452634,-0.6786074245996516,-0.16915765752368028,0.25591244186398043,0.5536355300185024,0.5801743268480191,1.0695626309218393,0.6330026427578571,-0.74037215539053,-0.14008827619228245,0.6330026427578571,2.8366888054205845,-0.05350303097992167,0.6855048182603979,-0.8650123589926522,0.44662661518260455,0.5003038219140473,0.5003038219140473,-1.2475690670035406,-0.2276042406016599,0.8153801473078209,0.5270123572912739,0.14483658048926837,0.44662661518260455,0.03213471430384632,0.5003038219140473,-0.08226034641678645,0.8153801473078209,-0.08226034641678645,2.1146206568398127,0.0036951455715587326,0.7376880792986121,-0.9594503693142111,1.5103236781354623,-0.43533889653030694,0.14483658048926837,-0.14008827619228245,0.28343716336325137,-0.05350303097992167,-0.05350303097992167,-0.43533889653030694,-1.3451743358044173,-0.49557962951464074,-0.8025083410499405,0.03213471430384632,-1.1829292935550804,0.11681693759758847,0.2005724364337766,-0.14008827619228245,0.5270123572912739,-0.5866649642761562,-0.4053649182267038,-0.5866649642761562,0.7376880792986121,0.5003038219140473,-0.28645733903368353,0.5270123572912739
3,375
Antigen processing ubiquitination proteasome degradation
23
95
2.710012
0.006728
P28072,Q7Z7E8,Q96J02,Q99436,P20618,P55786,Q9UII4,P49427,P63208,Q6UWE0,Q9UJX6,P49721,P28074,Q92530,P46934,P28070,Q14997,Q14999,P60900,Q15386,Q9UIQ6,Q12834,O94822
Processes and pathways
Reactome Pathways
msigdb_reactome
129,528,670,672,147,22,295,656,660,169,305,59,557,63,447,205,212,216,597,343,100,222,114
1219,941,2258,2366,2022,2789,1165,784,114,2700,1713,1485,2583,147,1719,1425,786,1227,1426,2795,205,129,557,1322,909,2769,2276,447,992,656,686,59,1552,950,2326,22,911,597,2169,2667,3121,752,2742,2222,1604,660,1810,915,1440,222,1331,2123,1974,1559,1816,2435,1868,1501,212,216,1076,2338,1040,2054,343,1446,2057,1448,169,3138,1044,528,1510,63,1244,1927,670,672,1686,1762,847,1631,2784,295,100,1217,1404,1940,305,1155,1472,1099,1311,2414,1410
0.2005724364337766,0.36544472945786843,-0.3160348969490162,-0.3754892338100565,-0.1983298434546702,-0.7094431280794159,0.22829128088385117,0.47350891704813686,1.9782122047843376,-0.6172178657741221,-0.05350303097992167,0.060467414101225296,-0.5258453497283577,1.700034827064007,-0.05350303097992167,0.08869434652356714,0.47350891704813686,0.2005724364337766,0.08869434652356714,-0.7094431280794159,1.4141012478824513,1.8400454612708395,0.6592940398904245,0.14483658048926837,0.39259560337501387,-0.6786074245996516,-0.3160348969490162,0.8153801473078209,0.33820212925301407,0.5801743268480191,0.5536355300185024,2.5358424878703127,0.03213471430384632,0.36544472945786843,-0.34571237893882045,3.4171394805890736,0.39259560337501387,0.6330026427578571,-0.2569802644281954,-0.5866649642761562,-1.1829292935550804,0.5003038219140473,-0.6478655125716591,-0.28645733903368353,0.0036951455715587326,0.5801743268480191,-0.08226034641678645,0.39259560337501387,0.08869434652356714,1.3169237397506999,0.14483658048926837,-0.2276042406016599,-0.16915765752368028,0.03213471430384632,-0.08226034641678645,-0.4053649182267038,-0.11112230190969725,0.060467414101225296,1.3656340456729201,1.3413095590408202,0.28343716336325137,-0.34571237893882045,0.31086666228014365,-0.1983298434546702,0.9940553151106681,0.08869434652356714,-0.1983298434546702,0.08869434652356714,1.5580872461878,-1.2152058878452634,0.31086666228014365,0.7116358722612617,0.060467414101225296,2.514056875953885,0.2005724364337766,-0.14008827619228245,0.5801743268480191,0.5801743268480191,-0.024850986633067236,-0.05350303097992167,0.44662661518260455,0.0036951455715587326,-0.6786074245996516,1.0945945877969334,2.1146206568398127,0.22829128088385117,0.11681693759758847,-0.14008827619228245,1.0695626309218393,0.25591244186398043,0.08869434652356714,0.28343716336325137,0.17275463656922826,-0.3754892338100565,0.11681693759758847
3,375
Protein targeting
36
120
2.707761
0.006774
O60830,Q15005,Q9H9H4,P20645,Q9Y4C2,Q7Z3T8,P31751,P49840,P50542,O43933,P55786,Q5JRX3,Q15629,Q99595,Q9NS69,Q14108,O14925,Q15388,Q10713,Q99442,Q96RL7,P46934,O60725,Q9UJ83,Q00535,O00170,P46379,P43307,Q9Y512,Q9UHD1,Q96EP0,P27105,Q9H0F7,Q8N4H5,P49257,Q8N3F8
Processes and pathways
GO Biological process
msigdb_gobp
0,506,673,137,681,143,148,273,522,145,22,281,154,28,29,31,284,288,414,577,58,447,82,473,599,585,91,593,371,369,635,479,637,485,621,124
974,897,3276,585,858,1708,645,2367,2657,284,1104,3367,2370,683,1951,145,82,0,1787,1263,2153,1956,1713,2098,1850,1264,2267,2422,3237,2314,1489,137,479,1228,946,1176,1860,148,2273,3061,1902,2320,826,593,91,447,621,2798,273,522,2801,2220,22,1494,1735,2511,1383,2836,2710,3163,2589,1810,599,414,1557,1038,31,506,1288,288,154,3151,1978,881,1503,281,1506,837,2805,143,1044,803,1296,124,485,1242,1341,3272,635,58,577,1516,1687,28,2136,1834,734,637,673,3077,2726,29,1254,1097,2613,1775,1016,369,3325,473,1777,2692,1405,2762,681,371,2085,2788,3111,938
0.33820212925301407,0.39259560337501387,-1.7095397473437453,0.6330026427578571,0.41965586752605055,-0.05350303097992167,0.5801743268480191,-0.3754892338100565,-0.5866649642761562,1.0945945877969334,0.25591244186398043,-4.204814994147441,-0.3754892338100565,0.5536355300185024,-0.16915765752368028,1.700034827064007,2.249349781196953,6.177852396500397,-0.08226034641678645,0.17275463656922826,-0.2569802644281954,-0.16915765752368028,-0.05350303097992167,-0.2276042406016599,-0.11112230190969725,0.17275463656922826,-0.3160348969490162,-0.4053649182267038,-1.5095468498520557,-0.34571237893882045,0.060467414101225296,1.7935845599756126,0.7636623002448963,0.2005724364337766,0.36544472945786843,0.22829128088385117,-0.11112230190969725,1.700034827064007,-0.3160348969490162,-1.0546965194844964,-0.14008827619228245,-0.34571237893882045,0.44662661518260455,0.6330026427578571,2.182190438903513,0.8153801473078209,0.6066297150102449,-0.7094431280794159,1.144456813443884,0.7116358722612617,-0.7094431280794159,-0.28645733903368353,3.4171394805890736,0.060467414101225296,-0.05350303097992167,-0.4654106405661174,0.11681693759758847,-0.74037215539053,-0.6172178657741221,-1.2800184510915182,-0.5258453497283577,-0.08226034641678645,0.6330026427578571,0.8667959860819097,0.03213471430384632,0.31086666228014365,3.1509596999717213,0.7376880792986121,0.17275463656922826,1.0945945877969334,1.6529390108089894,-1.2475690670035406,-0.16915765752368028,0.41965586752605055,0.060467414101225296,1.1195590959099642,0.060467414101225296,0.44662661518260455,-0.7094431280794159,1.7235018312297918,0.31086666228014365,0.47350891704813686,0.17275463656922826,1.8863015470497642,0.7636623002448963,0.2005724364337766,0.14483658048926837,-1.6760024115861647,0.6066297150102449,2.557587398973077,0.6592940398904245,0.060467414101225296,-0.024850986633067236,3.294970582891578,-0.2276042406016599,-0.08226034641678645,0.5270123572912739,0.6066297150102449,0.5801743268480191,-1.0546965194844964,-0.6172178657741221,3.2539898346567666,0.2005724364337766,0.28343716336325137,-0.5258453497283577,-0.05350303097992167,0.33820212925301407,0.9433672737733582,-2.2918606479305406,0.7895593798784971,-0.05350303097992167,-0.5866649642761562,0.11681693759758847,-0.6478655125716591,0.5801743268480191,0.9433672737733582,-0.1983298434546702,-0.6786074245996516,-1.150739668468142,0.39259560337501387
3,375
metalloprotease
8
27
2.705685
0.006816
Q9NZ08,Q9UIQ6,Q9BYT8,P42892,Q7Z2K6,P55786,O75844,Q5JRX3
Functions
Panther Protein class
panther_protein_class
204,100,402,50,116,22,88,281
615,1787,88,589,1113,1895,1539,1174,3039,1033,50,950,22,414,281,3234,116,1198,1138,1930,2136,402,1937,1152,204,100,2018
0.6066297150102449,-0.08226034641678645,2.2046220417723954,0.6330026427578571,0.25591244186398043,-0.14008827619228245,0.03213471430384632,0.22829128088385117,-1.0228587054425817,0.31086666228014365,2.622580671152067,0.36544472945786843,3.4171394805890736,0.8667959860819097,1.1195590959099642,-1.4765043166587404,1.9782122047843376,0.22829128088385117,0.25591244186398043,-0.14008827619228245,-0.2276042406016599,0.8923926409127418,-0.14008827619228245,0.25591244186398043,1.4382450552811312,2.1146206568398127,-0.16915765752368028
3,375
Outer membrane
22
95
2.704255
0.006846
Q13505,Q99720,P52789,P21796,Q9NS69,Q8WY22,Q9HCL2,Q15388,Q9NX47,Q9NZ45,Q9UBM7,Q96RL7,P50416,P45880,Q6SZW1,P09601,Q7Z434,Q86UT6,Q6NUM9,Q9Y512,Q9H974,Q99536
Localization
GO Cellular component
msigdb_gocc
8,12,396,24,29,30,172,288,304,52,57,58,311,62,200,68,202,333,223,371,387,384
3276,1157,1475,1160,1414,1532,1478,2732,2153,1956,983,1264,1536,2543,1421,68,905,24,1176,988,3148,1034,1963,62,413,311,396,3041,1494,913,1387,1281,8,1819,288,3151,2185,1918,1503,3201,2235,3240,223,200,1238,202,333,3221,3097,2717,2347,1394,485,2845,2239,1341,1619,3363,3283,30,1397,3025,2961,58,1052,384,3203,12,1764,3003,3357,608,2298,1211,734,387,172,1697,29,1255,1150,1256,2453,304,2566,470,52,772,740,57,893,552,2762,371,584
-1.7095397473437453,0.22829128088385117,0.060467414101225296,0.22829128088385117,0.08869434652356714,0.03213471430384632,0.060467414101225296,-0.6478655125716591,-0.2569802644281954,-0.16915765752368028,0.33820212925301407,0.17275463656922826,0.03213471430384632,-0.49557962951464074,0.08869434652356714,2.4703624293785205,0.39259560337501387,3.356198648789754,0.22829128088385117,0.33820212925301407,-1.2475690670035406,0.31086666228014365,-0.16915765752368028,2.514056875953885,0.8667959860819097,1.0444625558272569,0.8923926409127418,-1.0228587054425817,0.060467414101225296,0.39259560337501387,0.11681693759758847,0.17275463656922826,4.204415092601044,-0.08226034641678645,1.0945945877969334,-1.2475690670035406,-0.2569802644281954,-0.14008827619228245,0.060467414101225296,-1.3778800978198302,-0.28645733903368353,-1.5095468498520557,1.3169237397506999,1.4382450552811312,0.2005724364337766,1.4382450552811312,1.0192936815049485,-1.4435454454021128,-1.1186374013991909,-0.6172178657741221,-0.34571237893882045,0.11681693759758847,0.7636623002448963,-0.74037215539053,-0.28645733903368353,0.14483658048926837,0.0036951455715587326,-3.633800904518086,-1.7768580132442235,3.192271858418881,0.11681693759758847,-0.9911098512078583,-0.8964011979097756,2.557587398973077,0.31086666228014365,0.91791615126421,-1.3778800978198302,3.9144271277439557,-0.05350303097992167,-0.9594503693142111,-3.261532807782791,0.6330026427578571,-0.3160348969490162,0.22829128088385117,0.5270123572912739,0.91791615126421,1.5580872461878,-0.024850986633067236,3.2539898346567666,0.2005724364337766,0.25591244186398043,0.2005724364337766,-0.4053649182267038,1.0695626309218393,-0.49557962951464074,0.7895593798784971,2.6009562194312528,0.5003038219140473,0.5270123572912739,2.5792918852390194,0.41965586752605055,0.6855048182603979,-0.6478655125716591,0.9433672737733582,0.6592940398904245
3,375
Signaling
9
19
2.695983
0.007018
P17931,Q7Z4V5,P43490,Q96PC5,Q13123,O15173,Q9UHD1,P42166,Q96GC9
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
256,263,594,335,415,195,369,328,84
1157,195,2499,256,328,594,1665,1387,1498,415,2185,2234,263,1454,84,699,335,1208,369
0.22829128088385117,1.4382450552811312,-0.4654106405661174,1.2187556408509548,1.0192936815049485,0.6330026427578571,-0.024850986633067236,0.11681693759758847,0.060467414101225296,0.8667959860819097,-0.2569802644281954,-0.28645733903368353,1.1940544547326637,0.08869434652356714,2.249349781196953,0.5536355300185024,1.0192936815049485,0.22829128088385117,0.9433672737733582
3,375
Mitochondrial transport
20
90
2.692445
0.007093
O60830,O43772,Q9UBX3,P49840,P23786,P52789,P55786,O75964,Q5JRX3,P49841,P00846,Q99595,Q9NS69,O14925,Q15388,P12235,P50416,P45880,Q9Y512,Q15070
Processes and pathways
GO Biological process
msigdb_gobp
0,15,144,273,20,396,22,393,281,157,156,28,29,284,288,54,311,62,371,378
3276,585,2367,284,3367,2370,15,0,2732,1787,3146,393,2153,1956,1713,2098,1850,1264,156,2733,865,3134,2267,1421,3237,54,1489,20,2109,3037,1545,1032,1176,1902,2916,1177,62,3135,2111,621,273,157,311,2220,396,22,561,2474,1810,414,1038,1190,378,288,3151,2185,881,1503,281,1614,1044,2717,2347,485,1242,1341,1005,3272,574,635,842,28,2136,1834,734,3077,1253,29,1097,2613,144,3325,2205,2729,1843,2762,371,2085,2788,3111
-1.7095397473437453,0.6330026427578571,-0.3754892338100565,1.0945945877969334,-4.204814994147441,-0.3754892338100565,3.697871107665648,6.177852396500397,-0.6478655125716591,-0.08226034641678645,-1.2475690670035406,0.8923926409127418,-0.2569802644281954,-0.16915765752368028,-0.05350303097992167,-0.2276042406016599,-0.11112230190969725,0.17275463656922826,1.6293092873800175,-0.6478655125716591,0.41965586752605055,-1.2152058878452634,-0.3160348969490162,0.08869434652356714,-1.5095468498520557,2.5792918852390194,0.060467414101225296,3.457609530408841,-0.2276042406016599,-1.0228587054425817,0.03213471430384632,0.31086666228014365,0.22829128088385117,-0.14008827619228245,-0.8337145938116572,0.22829128088385117,2.514056875953885,-1.2152058878452634,-0.2276042406016599,0.6066297150102449,1.144456813443884,1.6293092873800175,1.0444625558272569,-0.28645733903368353,0.8923926409127418,3.4171394805890736,0.6592940398904245,-0.43533889653030694,-0.08226034641678645,0.8667959860819097,0.31086666228014365,0.22829128088385117,0.91791615126421,1.0945945877969334,-1.2475690670035406,-0.2569802644281954,0.41965586752605055,0.060467414101225296,1.1195590959099642,0.0036951455715587326,0.31086666228014365,-0.6172178657741221,-0.34571237893882045,0.7636623002448963,0.2005724364337766,0.14483658048926837,0.33820212925301407,-1.6760024115861647,0.6592940398904245,0.6066297150102449,0.44662661518260455,3.294970582891578,-0.2276042406016599,-0.08226034641678645,0.5270123572912739,-1.0546965194844964,0.2005724364337766,3.2539898346567666,0.28343716336325137,-0.5258453497283577,1.7235018312297918,-2.2918606479305406,-0.2569802644281954,-0.6172178657741221,-0.08226034641678645,-0.6478655125716591,0.9433672737733582,-0.1983298434546702,-0.6786074245996516,-1.150739668468142
3,375
Hand polydactyly
11
34
2.680701
0.007347
Q9BXW9,O96028,Q9Y263,Q8NCM8,Q10713,Q14739,Q8WXW3,Q9UHX1,Q9UBM7,Q12768,Q92766
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
292,65,338,379,414,174,318,349,57,181,382
940,2576,2027,65,1490,907,2217,1379,2325,1384,414,181,956,1815,174,2336,799,1240,570,1753,379,318,382,439,2532,292,637,2198,2687,57,349,1355,3109,338
0.36544472945786843,-0.5258453497283577,-0.1983298434546702,2.4922302839791723,0.060467414101225296,0.39259560337501387,-0.28645733903368353,0.11681693759758847,-0.34571237893882045,0.11681693759758847,0.8667959860819097,1.5103236781354623,0.36544472945786843,-0.08226034641678645,1.5342340098871912,-0.34571237893882045,0.47350891704813686,0.2005724364337766,0.6592940398904245,-0.05350303097992167,0.91791615126421,1.0444625558272569,0.91791615126421,0.8411254163810149,-0.4654106405661174,1.0945945877969334,0.6066297150102449,-0.2569802644281954,-0.5866649642761562,2.5792918852390194,0.9940553151106681,0.14483658048926837,-1.150739668468142,1.0192936815049485
3,375
Protein methyltransferase activity
17
26
2.676879
0.007431
Q86X55,Q9BV86,O14744,O96028,O15047,Q52LJ0,O60678,Q8NCA5,Q15047,Q9H993,Q99873,Q8WTS6,O60725,Q6UXN9,Q9H7B4,Q9UBL3,Q9UI30
Functions
GO Molecular function
msigdb_gomf
1045,160,778,65,499,419,782,486,601,767,606,963,82,1001,967,283,194
778,499,782,82,65,2736,1542,1035,1497,2231,1287,601,1191,419,1678,1001,1195,1045,486,963,606,160,967,767,283,194
0.47350891704813686,0.7376880792986121,0.47350891704813686,2.249349781196953,2.4922302839791723,-0.6478655125716591,0.03213471430384632,0.31086666228014365,0.060467414101225296,-0.28645733903368353,0.17275463656922826,0.6330026427578571,0.22829128088385117,0.8667959860819097,-0.024850986633067236,0.33820212925301407,0.22829128088385117,0.31086666228014365,0.7636623002448963,0.36544472945786843,0.6330026427578571,1.6056244017080097,0.36544472945786843,0.5003038219140473,1.1195590959099642,1.4623297140439213
3,375
Inorganic anion transmembrane transporter activity
9
19
2.661286
0.007784
Q8TDW0,Q6N075,Q9C0H2,Q9UBX3,Q4KMQ2,P21796,P51798,P0CG08,P45880
Functions
GO Molecular function
msigdb_gomf
530,361,80,144,360,24,180,340,62
898,1709,683,340,24,62,180,2168,1280,360,361,530,3222,80,1310,144,552,776,1586
0.39259560337501387,-0.05350303097992167,0.5536355300185024,0.9940553151106681,3.356198648789754,2.514056875953885,1.5103236781354623,-0.2569802644281954,0.17275463656922826,0.9433672737733582,0.9433672737733582,0.7116358722612617,-1.4435454454021128,2.2716465763795988,0.17275463656922826,1.7235018312297918,0.6855048182603979,0.5003038219140473,0.03213471430384632
3,375
Corneal opacity
22
50
2.65404
0.007953
Q03001,Q86XI2,P04066,Q9Y4P3,P50542,O43933,Q06136,P08236,O14802,P09884,Q9UBM7,P06280,O60566,P35250,O75569,O96028,P10619,P16278,O75844,P53701,P04062,P19447
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
623,134,266,408,522,145,280,650,779,785,57,432,431,558,307,65,196,207,88,237,358,747
3187,779,1531,1223,1020,145,431,1480,307,88,1111,2027,65,2878,358,266,432,650,785,196,207,2546,747,558,3093,826,522,1120,1279,237,1806,2887,1669,623,280,1815,2890,1562,1236,957,1614,2289,134,2198,1700,2492,57,2251,1355,408
-1.3451743358044173,0.47350891704813686,0.03213471430384632,0.2005724364337766,0.31086666228014365,1.700034827064007,0.8411254163810149,0.060467414101225296,1.0444625558272569,2.2046220417723954,0.25591244186398043,-0.1983298434546702,2.4922302839791723,-0.8025083410499405,0.9433672737733582,1.1692883875750077,0.8411254163810149,0.5801743268480191,0.47350891704813686,1.4382450552811312,1.3898977585599475,-0.49557962951464074,0.5003038219140473,0.6592940398904245,-1.1186374013991909,0.44662661518260455,0.7116358722612617,0.25591244186398043,0.17275463656922826,1.2679658226874506,-0.08226034641678645,-0.8025083410499405,-0.024850986633067236,0.6066297150102449,1.1195590959099642,-0.08226034641678645,-0.8025083410499405,0.03213471430384632,0.2005724364337766,0.36544472945786843,0.0036951455715587326,-0.3160348969490162,1.8168408195595176,-0.2569802644281954,-0.024850986633067236,-0.43533889653030694,2.5792918852390194,-0.28645733903368353,0.14483658048926837,0.8923926409127418
3,375
Vascular skin abnormality
46
123
2.649061
0.008072
Q13126,Q06330,Q07864,P04066,P48651,Q06136,Q9NWM8,Q9Y5L0,P00846,Q14108,Q9BXW9,O14802,P00403,P09884,Q14739,Q96JJ3,Q15833,Q92890,Q8WVM7,Q9UBM7,P06280,P51798,O94761,P03886,Q9Y487,P10619,P28340,P16278,P19838,O75844,O00170,P31153,Q06124,O15360,P53701,Q6KC79,Q9H9E3,P04062,O75306,P19447,Q96MW5,P49257,P38435,P17252,Q92766,Q8NCH0
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
1,624,753,266,141,280,813,818,156,31,292,779,538,785,174,699,175,439,317,57,432,180,554,71,741,196,825,207,715,88,585,592,877,477,237,630,768,358,861,747,247,621,245,870,382,126
585,940,779,477,1109,2854,1953,2210,2093,861,2311,88,554,1368,1849,1369,538,156,2878,71,358,266,432,3262,785,196,1027,1487,1895,2106,207,870,1794,2546,747,715,1172,1490,1115,907,1226,3083,825,2379,592,2833,1903,1117,3093,2859,2860,245,1428,1726,141,621,875,2322,1120,180,1730,237,1379,2325,1806,951,3136,2383,1741,2974,877,280,624,753,1187,2180,1,1915,31,1869,3200,2516,174,2436,1819,1192,3210,1335,175,2519,2924,630,1614,1747,1988,1082,1615,126,317,382,439,1462,2721,699,1685,247,2527,1209,1141,292,1578,2784,768,2903,813,2492,1096,57,2568,2693,2016,741,818
0.6330026427578571,0.36544472945786843,0.47350891704813686,0.7636623002448963,0.25591244186398043,-0.771394044942476,-0.16915765752368028,-0.28645733903368353,-0.2276042406016599,0.41965586752605055,-0.34571237893882045,2.2046220417723954,0.6592940398904245,0.11681693759758847,-0.11112230190969725,0.11681693759758847,0.6855048182603979,1.6293092873800175,-0.8025083410499405,2.404508413104643,0.9433672737733582,1.1692883875750077,0.8411254163810149,-1.6425467075224687,0.47350891704813686,1.4382450552811312,0.31086666228014365,0.060467414101225296,-0.14008827619228245,-0.2276042406016599,1.3898977585599475,0.41965586752605055,-0.08226034641678645,-0.49557962951464074,0.5003038219140473,0.5270123572912739,0.22829128088385117,0.060467414101225296,0.25591244186398043,0.39259560337501387,0.2005724364337766,-1.0866228857275761,0.44662661518260455,-0.3754892338100565,0.6330026427578571,-0.74037215539053,-0.14008827619228245,0.25591244186398043,-1.1186374013991909,-0.771394044942476,-0.771394044942476,1.24339256161293,0.08869434652356714,-0.05350303097992167,1.7235018312297918,0.6066297150102449,0.41965586752605055,-0.34571237893882045,0.25591244186398043,1.5103236781354623,-0.05350303097992167,1.2679658226874506,0.11681693759758847,-0.34571237893882045,-0.08226034641678645,0.36544472945786843,-1.2152058878452634,-0.3754892338100565,-0.05350303097992167,-0.9278806773204062,0.41965586752605055,1.1195590959099642,0.6066297150102449,0.5003038219140473,0.22829128088385117,-0.2569802644281954,5.487805323059808,-0.14008827619228245,3.1509596999717213,-0.11112230190969725,-1.3778800978198302,-0.4654106405661174,1.5342340098871912,-0.4053649182267038,-0.08226034641678645,0.22829128088385117,-1.4106705873943675,0.14483658048926837,1.5342340098871912,-0.4654106405661174,-0.8337145938116572,0.6066297150102449,0.0036951455715587326,-0.05350303097992167,-0.16915765752368028,0.28343716336325137,0.0036951455715587326,1.8631989005372565,1.0444625558272569,0.91791615126421,0.8411254163810149,0.08869434652356714,-0.6172178657741221,0.5536355300185024,-0.024850986633067236,1.24339256161293,-0.4654106405661174,0.22829128088385117,0.25591244186398043,1.0945945877969334,0.03213471430384632,-0.6786074245996516,0.5003038219140473,-0.8025083410499405,0.47350891704813686,-0.43533889653030694,0.28343716336325137,2.5792918852390194,-0.49557962951464074,-0.5866649642761562,-0.16915765752368028,0.5270123572912739,0.47350891704813686
3,375
Cholesterol biosynthesis
8
18
2.640729
0.008273
P48449,Q9H2C2,P37268,Q14739,Q15392,Q9UBM7,Q16850,P04035
Processes and pathways
Reactome Pathways
msigdb_reactome
32,404,412,174,51,57,186,253
2501,253,2315,412,32,2510,2940,1916,724,174,2126,51,1335,2635,186,454,404,57
-0.4654106405661174,1.2187556408509548,-0.34571237893882045,0.8667959860819097,3.130252972308468,-0.4654106405661174,-0.8650123589926522,-0.14008827619228245,0.5270123572912739,1.5342340098871912,-0.2276042406016599,2.6009562194312528,0.14483658048926837,-0.5562072945734238,1.486355749287792,0.8153801473078209,0.8923926409127418,2.5792918852390194
3,375
Cellular monovalent inorganic cation homeostasis
9
25
2.638889
0.008318
O75503,Q92544,P61421,Q9HC07,Q9UI12,Q8N511,P50897,Q93050,P0CG08
Processes and pathways
GO Biological process
msigdb_gobp
98,356,287,302,235,178,55,155,340
98,1848,2461,2619,3134,340,1799,2379,55,2801,2045,2168,287,915,1336,178,356,155,730,302,369,235,741,776,1586
2.1146206568398127,-0.11112230190969725,-0.43533889653030694,-0.5562072945734238,-1.2152058878452634,0.9940553151106681,-0.08226034641678645,-0.3754892338100565,2.5792918852390194,-0.7094431280794159,-0.1983298434546702,-0.2569802644281954,1.0945945877969334,0.39259560337501387,0.14483658048926837,1.5342340098871912,0.9687467516697891,1.6529390108089894,0.5270123572912739,1.0695626309218393,0.9433672737733582,1.292476019958997,0.5270123572912739,0.5003038219140473,0.03213471430384632
3,375
Cholesterol metabolism with bloch and kandutschrussell pathways
8
24
2.637997
0.00834
P48449,P35610,P37268,Q14739,Q15392,Q9UBM7,Q16850,P04035
Processes and pathways
WikiPathways
msigdb_wp
32,102,412,174,51,57,186,253
2617,1478,983,2501,903,253,2315,988,102,412,32,875,2510,2940,1916,724,174,2126,51,1335,2635,186,454,57
-0.5562072945734238,0.060467414101225296,0.33820212925301407,-0.4654106405661174,0.39259560337501387,1.2187556408509548,-0.34571237893882045,0.33820212925301407,2.092004590409298,0.8667959860819097,3.130252972308468,0.41965586752605055,-0.4654106405661174,-0.8650123589926522,-0.14008827619228245,0.5270123572912739,1.5342340098871912,-0.2276042406016599,2.6009562194312528,0.14483658048926837,-0.5562072945734238,1.486355749287792,0.8153801473078209,2.5792918852390194
3,375
Sterol biosynthetic process
7
25
2.627059
0.008613
P48449,Q9H2C2,Q14739,Q15392,Q9UBM7,Q16850,P04035
Processes and pathways
GO Biological process
msigdb_gobp
32,404,174,51,57,186,253
1954,3112,1536,253,1657,2315,1540,412,1177,32,1180,2510,2940,1038,1916,724,174,2126,51,1335,2635,186,404,57,1841
-0.16915765752368028,-1.1829292935550804,0.03213471430384632,1.2187556408509548,-0.024850986633067236,-0.34571237893882045,0.03213471430384632,0.8667959860819097,0.22829128088385117,3.130252972308468,0.22829128088385117,-0.4654106405661174,-0.8650123589926522,0.31086666228014365,-0.14008827619228245,0.5270123572912739,1.5342340098871912,-0.2276042406016599,2.6009562194312528,0.14483658048926837,-0.5562072945734238,1.486355749287792,0.8923926409127418,2.5792918852390194,-0.08226034641678645
3,375
Cellular lipid metabolic process
53
215
2.621859
0.008745
P14174,Q8WTV0,Q8NCC3,Q9H2C2,P04066,P09455,P35790,P48651,P31751,P23786,Q06136,A1L0T0,P48449,Q9NPH0,Q99805,Q9HCL2,Q10713,P37268,Q14914,Q8WXW3,Q6IAN0,P06280,P50897,P50416,Q2TAA5,Q9NRA0,Q9BWD1,Q9HB40,Q9Y263,Q96N66,Q96G23,P49748,O94788,P07099,Q16739,P16278,Q9NXE4,Q9BYI3,O75844,Q8TC12,Q86YN1,Q8NHP8,Q6NUM9,P35610,Q9UHD1,Q9BT22,Q9C0D9,P04062,Q8NBX0,Q9BY49,O75376,P04035,Q9Y394
Processes and pathways
GO Biological process
msigdb_gobp
255,6,7,404,266,267,13,141,148,20,280,391,32,35,36,172,414,412,45,318,315,432,55,311,313,193,454,67,338,453,70,448,75,76,78,207,470,86,88,226,224,99,223,102,369,365,109,358,120,385,252,253,127
391,857,1103,896,1220,1160,2617,1221,1648,1162,1361,1163,2418,1164,2987,3367,1314,1478,782,1953,710,252,1954,1481,2152,88,2764,75,3112,1484,1316,983,2501,2212,903,253,358,266,2156,2313,2102,432,684,76,1420,3218,2580,267,3327,1266,3190,255,2315,2831,3333,207,1540,3257,2034,3293,1718,1898,20,2377,2378,1800,653,2110,2702,789,148,988,102,13,412,2937,1429,2665,1177,1118,2380,32,141,875,448,311,522,55,2919,1120,2167,1180,2510,1969,3041,2552,3298,2940,1669,877,280,414,3084,797,1038,2890,1916,918,45,799,1390,2438,2126,2865,2635,1129,2440,78,1980,663,313,3233,959,1503,1449,2520,315,223,1747,2130,2341,3152,2926,2716,224,529,1753,805,2869,3371,839,120,7,1996,508,99,226,6,2959,1571,1619,318,2898,2870,2720,2002,1462,1007,2005,3272,926,70,453,3127,2809,2562,1687,3203,3052,3335,36,2244,365,2564,1304,3373,3026,454,2299,385,86,3055,109,404,1148,3337,2072,67,172,35,2142,193,3079,1215,2986,1255,675,551,470,1636,2965,772,613,2144,740,678,854,369,473,2729,2206,338,127,1946,2417
0.8923926409127418,0.41965586752605055,0.25591244186398043,0.39259560337501387,0.2005724364337766,0.22829128088385117,-0.5562072945734238,0.2005724364337766,-0.024850986633067236,0.22829128088385117,0.11681693759758847,0.22829128088385117,-0.4053649182267038,0.22829128088385117,-0.9594503693142111,-4.204814994147441,0.14483658048926837,0.060467414101225296,0.47350891704813686,-0.16915765752368028,0.5270123572912739,1.2187556408509548,-0.16915765752368028,0.060467414101225296,-0.2569802644281954,2.2046220417723954,-0.6786074245996516,2.3382725296462423,-1.1829292935550804,0.060467414101225296,0.14483658048926837,0.33820212925301407,-0.4654106405661174,-0.28645733903368353,0.39259560337501387,1.2187556408509548,0.9433672737733582,1.1692883875750077,-0.2569802644281954,-0.34571237893882045,-0.2276042406016599,0.8411254163810149,0.5536355300185024,2.2938990874260146,0.08869434652356714,-1.4435454454021128,-0.5258453497283577,1.1692883875750077,-2.326814670181662,0.17275463656922826,-1.3451743358044173,1.2187556408509548,-0.34571237893882045,-0.74037215539053,-2.502718876001027,1.3898977585599475,0.03213471430384632,-1.609172964600143,-0.1983298434546702,-1.9124600034874841,-0.05350303097992167,-0.14008827619228245,3.457609530408841,-0.3754892338100565,-0.3754892338100565,-0.08226034641678645,0.5801743268480191,-0.2276042406016599,-0.6172178657741221,0.47350891704813686,1.700034827064007,0.33820212925301407,2.092004590409298,3.7572720143403053,0.8667959860819097,-0.8650123589926522,0.08869434652356714,-0.5866649642761562,0.22829128088385117,0.25591244186398043,-0.3754892338100565,3.130252972308468,1.7235018312297918,0.41965586752605055,0.8153801473078209,1.0444625558272569,0.7116358722612617,2.5792918852390194,-0.8337145938116572,0.25591244186398043,-0.2569802644281954,0.22829128088385117,-0.4654106405661174,-0.16915765752368028,-1.0228587054425817,-0.49557962951464074,-1.9465598176439003,-0.8650123589926522,-0.024850986633067236,0.41965586752605055,1.1195590959099642,0.8667959860819097,-1.0866228857275761,0.47350891704813686,0.31086666228014365,-0.8025083410499405,-0.14008827619228245,0.39259560337501387,2.751504561863883,0.47350891704813686,0.11681693759758847,-0.4053649182267038,-0.2276042406016599,-0.771394044942476,-0.5562072945734238,0.25591244186398043,-0.4053649182267038,2.2716465763795988,-0.16915765752368028,0.5801743268480191,1.0444625558272569,-1.4765043166587404,0.36544472945786843,0.060467414101225296,0.08869434652356714,-0.4654106405661174,1.0444625558272569,1.3169237397506999,-0.05350303097992167,-0.2276042406016599,-0.34571237893882045,-1.2475690670035406,-0.8337145938116572,-0.6172178657741221,1.3169237397506999,0.7116358722612617,-0.05350303097992167,0.47350891704813686,-0.771394044942476,-5.756231581515605,0.44662661518260455,1.9093538048745637,4.337756409373861,-0.16915765752368028,0.7376880792986121,2.1146206568398127,1.3169237397506999,4.432259380667763,-0.8964011979097756,0.03213471430384632,0.0036951455715587326,1.0444625558272569,-0.8025083410499405,-0.771394044942476,-0.6172178657741221,-0.16915765752368028,0.08869434652356714,0.33820212925301407,-0.16915765752368028,-1.6760024115861647,0.39259560337501387,2.426501785073673,0.8153801473078209,-1.1829292935550804,-0.7094431280794159,-0.49557962951464074,-0.024850986633067236,-1.3778800978198302,-1.0228587054425817,-2.502718876001027,3.0262046723466742,-0.28645733903368353,0.9433672737733582,-0.49557962951464074,0.17275463656922826,-10.357023878767876,-0.9911098512078583,0.8153801473078209,-0.3160348969490162,0.91791615126421,2.2270083787382036,-1.0228587054425817,2.0238730257815676,0.8923926409127418,0.25591244186398043,-2.502718876001027,-0.1983298434546702,2.4922302839791723,1.5580872461878,3.0887372059217104,-0.2276042406016599,1.4623297140439213,-1.0546965194844964,0.22829128088385117,-0.9278806773204062,0.2005724364337766,0.5801743268480191,0.6855048182603979,0.7895593798784971,0.0036951455715587326,-0.8964011979097756,0.5003038219140473,0.6330026427578571,-0.2276042406016599,0.5270123572912739,0.5801743268480191,0.44662661518260455,0.9433672737733582,0.7895593798784971,-0.6172178657741221,-0.2569802644281954,1.0192936815049485,1.8631989005372565,-0.14008827619228245,-0.3754892338100565
3,375
Regulation of dendrite morphogenesis
7
17
2.621789
0.008747
Q6SZW1,P46934,Q9UJX6,Q9Y4G8,Q14999,Q9UQB8,P49841
Processes and pathways
GO Biological process
msigdb_gobp
200,447,305,14,216,90,157
2658,1118,447,157,1231,1912,483,2595,216,2518,200,1766,1637,305,2494,90,14
-0.5866649642761562,0.25591244186398043,0.8153801473078209,1.6293092873800175,0.2005724364337766,-0.14008827619228245,0.7636623002448963,-0.5258453497283577,1.3413095590408202,-0.4654106405661174,1.4382450552811312,-0.05350303097992167,0.0036951455715587326,1.0695626309218393,-0.43533889653030694,2.2046220417723954,3.737500508749279
3,375
Alzheimers disease
24
86
2.619274
0.008812
P28072,Q9Y4P8,Q99436,P31751,P20618,P21796,Q9Y277,P49841,Q16186,P12236,Q9UJX6,P05067,P12235,P49720,P49721,P45880,P28074,P28070,Q00535,P60900,Q96BY7,O95197,Q08209,P07384
Processes and pathways
WikiPathways
msigdb_wp
129,409,672,148,147,24,552,157,662,541,305,166,54,686,59,62,557,205,599,597,487,588,483,123
2258,2366,2022,2088,2789,1165,588,2266,166,865,2029,123,1026,3227,54,541,1539,1064,3257,2583,2584,1489,715,147,24,1425,786,1227,1426,1799,2795,205,129,557,2379,1545,148,1547,1903,2769,1801,1034,948,2276,62,992,827,875,686,59,157,1552,2326,597,2742,2222,1604,1740,1072,599,1741,1186,483,2178,1498,1331,2891,997,918,1076,662,1823,2446,487,672,1686,1687,3052,1763,1143,2450,1886,305,2414,552,409
-0.3160348969490162,-0.3754892338100565,-0.1983298434546702,-0.2276042406016599,-0.7094431280794159,0.22829128088385117,0.6330026427578571,-0.3160348969490162,1.5580872461878,0.41965586752605055,-0.1983298434546702,1.8863015470497642,0.31086666228014365,-1.4765043166587404,2.5792918852390194,0.6855048182603979,0.03213471430384632,0.28343716336325137,-1.609172964600143,-0.5258453497283577,-0.5258453497283577,0.060467414101225296,0.5270123572912739,1.700034827064007,3.356198648789754,0.08869434652356714,0.47350891704813686,0.2005724364337766,0.08869434652356714,-0.08226034641678645,-0.7094431280794159,1.4141012478824513,1.8400454612708395,0.6592940398904245,-0.3754892338100565,0.03213471430384632,1.700034827064007,0.03213471430384632,-0.14008827619228245,-0.6786074245996516,-0.08226034641678645,0.31086666228014365,0.36544472945786843,-0.3160348969490162,2.514056875953885,0.33820212925301407,0.44662661518260455,0.41965586752605055,0.5536355300185024,2.5358424878703127,1.6293092873800175,0.03213471430384632,-0.34571237893882045,0.6330026427578571,-0.6478655125716591,-0.28645733903368353,0.0036951455715587326,-0.05350303097992167,0.28343716336325137,0.6330026427578571,-0.05350303097992167,0.22829128088385117,0.7636623002448963,-0.2569802644281954,0.060467414101225296,0.14483658048926837,-0.8025083410499405,0.33820212925301407,0.39259560337501387,0.28343716336325137,0.5801743268480191,-0.08226034641678645,-0.4053649182267038,0.7636623002448963,0.5801743268480191,-0.024850986633067236,-0.024850986633067236,-1.0228587054425817,-0.05350303097992167,0.25591244186398043,-0.4053649182267038,-0.11112230190969725,1.0695626309218393,-0.3754892338100565,0.6855048182603979,0.8923926409127418
3,375
Glucose metabolic process
15
55
2.614475
0.008936
P53007,Q92520,Q16531,Q00796,Q9BRR6,P10253,Q9BYT8,Q9UBX3,P31751,P49840,P52789,Q7Z4W1,O75844,P50416,P49841
Processes and pathways
GO Biological process
msigdb_gobp
162,451,449,261,103,231,402,144,148,273,396,117,88,311,157
857,3254,1160,1785,1847,88,2312,2266,2733,2543,2158,824,2374,231,2879,1028,3327,1657,2033,1371,905,148,1802,1432,273,157,311,396,162,2115,1035,1910,2170,261,1439,2180,1038,1390,2438,449,2440,1980,884,117,451,1461,926,1684,103,402,1697,144,2205,516,1587
0.41965586752605055,-1.609172964600143,0.22829128088385117,-0.08226034641678645,-0.11112230190969725,2.2046220417723954,-0.34571237893882045,-0.3160348969490162,-0.6478655125716591,-0.49557962951464074,-0.2569802644281954,0.44662661518260455,-0.3754892338100565,1.292476019958997,-0.8025083410499405,0.31086666228014365,-2.326814670181662,-0.024850986633067236,-0.1983298434546702,0.11681693759758847,0.39259560337501387,1.700034827064007,-0.08226034641678645,0.08869434652356714,1.144456813443884,1.6293092873800175,1.0444625558272569,0.8923926409127418,1.5818838811891258,-0.2276042406016599,0.31086666228014365,-0.14008827619228245,-0.2569802644281954,1.1940544547326637,0.08869434652356714,-0.2569802644281954,0.31086666228014365,0.11681693759758847,-0.4053649182267038,0.8153801473078209,-0.4053649182267038,-0.16915765752368028,0.41965586752605055,1.9782122047843376,0.8153801473078209,0.08869434652356714,0.39259560337501387,-0.024850986633067236,2.092004590409298,0.8923926409127418,-0.024850986633067236,1.7235018312297918,-0.2569802644281954,0.7376880792986121,0.03213471430384632
3,375
Organic hydroxy compound biosynthetic process
12
55
2.613553
0.008961
P48449,P00374,Q9H2C2,Q14739,Q9Y4G8,P04062,Q15392,Q9UKG1,Q9UBM7,Q16850,P04035,Q9NRA0
Processes and pathways
GO Biological process
msigdb_gobp
32,131,404,174,14,358,51,184,57,186,253,193
857,1528,1648,2657,1164,2987,1954,3112,131,1536,253,358,746,714,1657,2315,1540,2623,715,1718,1898,653,872,2955,412,1177,32,1180,2510,2835,2940,1038,2890,1916,724,174,2126,51,1335,2635,1980,186,926,842,1575,2006,3052,404,2142,193,57,1841,184,14,2256
0.41965586752605055,0.03213471430384632,-0.024850986633067236,-0.5866649642761562,0.22829128088385117,-0.9594503693142111,-0.16915765752368028,-1.1829292935550804,1.8168408195595176,0.03213471430384632,1.2187556408509548,0.9433672737733582,0.5003038219140473,0.5270123572912739,-0.024850986633067236,-0.34571237893882045,0.03213471430384632,-0.5562072945734238,0.5270123572912739,-0.05350303097992167,-0.14008827619228245,0.5801743268480191,0.41965586752605055,-0.8964011979097756,0.8667959860819097,0.22829128088385117,3.130252972308468,0.22829128088385117,-0.4654106405661174,-0.74037215539053,-0.8650123589926522,0.31086666228014365,-0.8025083410499405,-0.14008827619228245,0.5270123572912739,1.5342340098871912,-0.2276042406016599,2.6009562194312528,0.14483658048926837,-0.5562072945734238,-0.16915765752368028,1.486355749287792,0.39259560337501387,0.44662661518260455,0.03213471430384632,-0.16915765752368028,-1.0228587054425817,0.8923926409127418,-0.2276042406016599,1.4623297140439213,2.5792918852390194,-0.08226034641678645,1.5103236781354623,3.737500508749279,-0.28645733903368353
3,375
Intrinsic component of mitochondrial membrane
17
51
2.611578
0.009013
O60830,Q9P0S2,O14925,Q9Y512,Q15388,Q13505,Q9Y2R0,Q9H3K2,Q6P4A7,Q9BWH2,O75880,Q9HC21,Q00325,P12235,P50416,Q99595,Q15070
Localization
GO Cellular component
msigdb_gocc
0,427,284,371,288,8,106,638,568,608,324,192,598,54,311,28,378
284,707,0,2732,324,2153,1956,616,1264,54,3148,311,1494,598,8,378,288,1129,2185,1918,1503,3201,3240,568,1238,3221,2717,2347,1823,1341,1760,28,1626,2402,3003,608,734,638,1884,3102,192,1253,1256,2566,427,854,893,106,2018,371,1587
1.0945945877969334,0.5270123572912739,6.177852396500397,-0.6478655125716591,1.0192936815049485,-0.2569802644281954,-0.16915765752368028,0.6066297150102449,0.17275463656922826,2.5792918852390194,-1.2475690670035406,1.0444625558272569,0.060467414101225296,0.6330026427578571,4.204415092601044,0.91791615126421,1.0945945877969334,0.25591244186398043,-0.2569802644281954,-0.14008827619228245,0.060467414101225296,-1.3778800978198302,-1.5095468498520557,0.6592940398904245,0.2005724364337766,-1.4435454454021128,-0.6172178657741221,-0.34571237893882045,-0.08226034641678645,0.14483658048926837,-0.05350303097992167,3.294970582891578,0.0036951455715587326,-0.3754892338100565,-0.9594503693142111,0.6330026427578571,0.5270123572912739,0.6066297150102449,-0.11112230190969725,-1.1186374013991909,1.4623297140439213,0.2005724364337766,0.2005724364337766,-0.49557962951464074,0.8667959860819097,0.44662661518260455,0.41965586752605055,2.069341535905874,-0.16915765752368028,0.9433672737733582,0.03213471430384632
3,375
Lytic vacuole organization
12
28
2.610797
0.009033
P11117,O14773,O75503,Q9HC07,P10253,P04062,Q8N511,Q12768,P50897,Q96ED9,Q9P253,Q14108
Processes and pathways
GO Biological process
msigdb_gobp
286,188,98,302,231,358,178,181,55,121,457,31
858,188,98,1848,358,3218,231,286,1034,55,2801,480,1738,181,31,918,2520,3202,178,730,121,842,2010,302,2949,457,2569,1944
0.41965586752605055,1.4623297140439213,2.1146206568398127,-0.11112230190969725,0.9433672737733582,-1.4435454454021128,1.292476019958997,1.0945945877969334,0.31086666228014365,2.5792918852390194,-0.7094431280794159,0.7636623002448963,-0.05350303097992167,1.5103236781354623,3.1509596999717213,0.39259560337501387,-0.4654106405661174,-1.3778800978198302,1.5342340098871912,0.5270123572912739,1.9093538048745637,0.44662661518260455,-0.16915765752368028,1.0695626309218393,-0.8650123589926522,0.8153801473078209,-0.49557962951464074,-0.14008827619228245
3,375
Phospholipid metabolism
6
43
2.60924
0.009074
Q9NPH0,Q8NCC3,P35790,P48651,Q9C0D9,Q8IV08
Processes and pathways
Reactome Pathways
msigdb_reactome
35,7,13,141,109,94
1220,1162,1163,1224,1489,1961,2990,13,1429,1274,141,1431,3041,1738,1740,1669,414,1503,2130,94,1753,7,1996,508,2959,1619,2870,453,3127,489,1687,1209,2244,2564,3026,3055,109,172,35,1215,1255,740,854
0.2005724364337766,0.22829128088385117,0.22829128088385117,0.2005724364337766,0.060467414101225296,-0.16915765752368028,-0.9594503693142111,3.7572720143403053,0.08869434652356714,0.17275463656922826,1.7235018312297918,0.08869434652356714,-1.0228587054425817,-0.05350303097992167,-0.05350303097992167,-0.024850986633067236,0.8667959860819097,0.060467414101225296,-0.2276042406016599,2.159713234494772,-0.05350303097992167,4.337756409373861,-0.16915765752368028,0.7376880792986121,-0.8964011979097756,0.0036951455715587326,-0.771394044942476,0.8153801473078209,-1.1829292935550804,0.7636623002448963,-0.024850986633067236,0.22829128088385117,-0.28645733903368353,-0.49557962951464074,-0.9911098512078583,-1.0228587054425817,2.0238730257815676,1.5580872461878,3.0887372059217104,0.22829128088385117,0.2005724364337766,0.5270123572912739,0.44662661518260455
3,375
Abnormal renal pelvis morphology
14
53
2.600914
0.009298
Q9H2M9,Q86XI2,Q8NCM8,Q16531,P21281,Q9UJX6,Q08209,O43933,P50542,P23786,Q9UBM7,Q12768,Q93008,Q8NCH0
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
493,134,379,449,446,305,483,145,522,20,57,181,452,126
779,1166,1531,145,2576,2659,863,822,554,1368,1540,2881,446,1490,20,748,1903,2217,1801,826,1600,991,522,995,1970,1603,1866,1384,1741,753,483,1187,181,2556,1819,1335,449,2234,2129,2598,134,1394,126,379,452,2527,3204,493,1936,57,305,1355,1359
0.47350891704813686,0.22829128088385117,0.03213471430384632,1.700034827064007,-0.5258453497283577,-0.5866649642761562,0.41965586752605055,0.44662661518260455,0.6592940398904245,0.11681693759758847,0.03213471430384632,-0.8025083410499405,0.8153801473078209,0.060467414101225296,3.457609530408841,0.5003038219140473,-0.14008827619228245,-0.28645733903368353,-0.08226034641678645,0.44662661518260455,0.0036951455715587326,0.33820212925301407,0.7116358722612617,0.33820212925301407,-0.16915765752368028,0.0036951455715587326,-0.11112230190969725,0.11681693759758847,-0.05350303097992167,0.5003038219140473,0.7636623002448963,0.22829128088385117,1.5103236781354623,-0.49557962951464074,-0.08226034641678645,0.14483658048926837,0.8153801473078209,-0.28645733903368353,-0.2276042406016599,-0.5258453497283577,1.8168408195595176,0.11681693759758847,1.8631989005372565,0.91791615126421,0.8153801473078209,-0.4654106405661174,-1.3778800978198302,0.7636623002448963,-0.14008827619228245,2.5792918852390194,1.0695626309218393,0.14483658048926837,0.14483658048926837
3,375
Cellular hormone metabolic process
6
19
2.597014
0.009404
Q8TC12,Q9HB40,Q6NUM9,O94788,P42892,Q9Y394
Processes and pathways
GO Biological process
msigdb_gobp
226,67,223,75,50,127
782,75,1316,267,2831,1176,50,2167,1190,959,223,839,1395,226,2898,3052,1304,67,127
0.47350891704813686,2.3382725296462423,0.14483658048926837,1.1692883875750077,-0.74037215539053,0.22829128088385117,2.622580671152067,-0.2569802644281954,0.22829128088385117,0.36544472945786843,1.3169237397506999,0.44662661518260455,0.11681693759758847,1.3169237397506999,-0.8025083410499405,-1.0228587054425817,0.17275463656922826,2.4922302839791723,1.8631989005372565
3,375
Vacuolar membrane
22
121
2.595519
0.009445
Q8WTV0,O15260,P42785,P20645,Q93050,Q14108,P11117,P61421,O15118,Q9NQX7,P42892,Q8N511,P51798,Q96RL7,Q9NRA0,P10619,Q96GC9,Q8IV08,O75503,Q9UIQ6,Q9UI12,P10253
Localization
GO Cellular component
msigdb_gocc
6,9,10,137,155,31,286,287,285,44,50,178,180,58,193,196,84,94,98,100,235,231
858,645,1221,285,9,2497,3225,1590,1653,460,1224,1534,98,1848,980,2096,3060,1714,358,2913,2953,1420,2031,2373,2103,1169,2914,231,196,286,2314,2105,137,446,1857,1719,479,2273,1547,2859,1428,1599,1430,1034,10,50,2471,2427,2801,180,2771,2772,1736,2512,1738,287,3136,2382,721,1037,1386,434,2922,1073,3359,31,1190,2520,1290,1082,94,1877,178,508,2061,6,727,2446,155,730,1512,669,84,842,58,1516,2357,1209,2564,3373,1053,1466,2450,3140,2012,1146,809,302,610,2849,44,193,2949,772,3156,2144,457,1353,235,100,1100,1777,3195,2569,3131,1405,2762,1944,741,2694,1312
0.41965586752605055,0.5801743268480191,0.2005724364337766,1.0945945877969334,4.069826366870343,-0.4654106405661174,-1.4765043166587404,0.0036951455715587326,-0.024850986633067236,0.7895593798784971,0.2005724364337766,0.03213471430384632,2.1146206568398127,-0.11112230190969725,0.33820212925301407,-0.2276042406016599,-1.0546965194844964,-0.05350303097992167,0.9433672737733582,-0.8337145938116572,-0.8964011979097756,0.08869434652356714,-0.1983298434546702,-0.3754892338100565,-0.2276042406016599,0.22829128088385117,-0.8337145938116572,1.292476019958997,1.4382450552811312,1.0945945877969334,-0.34571237893882045,-0.2276042406016599,1.7935845599756126,0.8153801473078209,-0.11112230190969725,-0.05350303097992167,0.7636623002448963,-0.3160348969490162,0.03213471430384632,-0.771394044942476,0.08869434652356714,0.0036951455715587326,0.08869434652356714,0.31086666228014365,4.011752901252815,2.622580671152067,-0.43533889653030694,-0.4053649182267038,-0.7094431280794159,1.5103236781354623,-0.6786074245996516,-0.6786074245996516,-0.05350303097992167,-0.4654106405661174,-0.05350303097992167,1.0945945877969334,-1.2152058878452634,-0.3754892338100565,0.5270123572912739,0.31086666228014365,0.11681693759758847,0.8411254163810149,-0.8337145938116572,0.28343716336325137,-3.4468093595254037,3.1509596999717213,0.22829128088385117,-0.4654106405661174,0.17275463656922826,0.28343716336325137,2.159713234494772,-0.11112230190969725,1.5342340098871912,0.7376880792986121,-0.1983298434546702,4.432259380667763,0.5270123572912739,-0.4053649182267038,1.6529390108089894,0.5270123572912739,0.060467414101225296,0.5801743268480191,2.249349781196953,0.44662661518260455,2.557587398973077,0.060467414101225296,-0.34571237893882045,0.22829128088385117,-0.49557962951464074,-10.357023878767876,0.31086666228014365,0.08869434652356714,-0.4053649182267038,-1.2152058878452634,-0.16915765752368028,0.25591244186398043,0.47350891704813686,1.0695626309218393,0.6330026427578571,-0.74037215539053,2.8366888054205845,1.4623297140439213,-0.8650123589926522,0.5003038219140473,-1.2475690670035406,-0.2276042406016599,0.8153801473078209,0.14483658048926837,1.292476019958997,2.1146206568398127,0.28343716336325137,-0.05350303097992167,-1.3451743358044173,-0.49557962951464074,-1.1829292935550804,0.11681693759758847,-0.6478655125716591,-0.14008827619228245,0.5270123572912739,-0.5866649642761562,0.17275463656922826
3,375
Secondary alcohol metabolic process
13
41
2.593598
0.009498
P48449,Q8WTV0,O15118,P35610,Q9H2C2,P37268,P05067,Q14739,P04062,Q15392,Q9UBM7,Q16850,P04035
Processes and pathways
GO Biological process
msigdb_gobp
32,6,285,102,404,412,166,174,358,51,57,186,253
285,2575,1954,2764,3112,1536,253,358,166,1657,2315,1540,2737,102,412,1177,32,3307,448,2165,1180,2510,3298,2175,2940,1038,1916,724,174,1190,1039,2126,51,1335,2635,186,6,2296,404,57,2950
1.0945945877969334,-0.5258453497283577,-0.16915765752368028,-0.6786074245996516,-1.1829292935550804,0.03213471430384632,1.2187556408509548,0.9433672737733582,1.5580872461878,-0.024850986633067236,-0.34571237893882045,0.03213471430384632,-0.6478655125716591,2.092004590409298,0.8667959860819097,0.22829128088385117,3.130252972308468,-2.0493327505938783,0.8153801473078209,-0.2569802644281954,0.22829128088385117,-0.4654106405661174,-1.9465598176439003,-0.2569802644281954,-0.8650123589926522,0.31086666228014365,-0.14008827619228245,0.5270123572912739,1.5342340098871912,0.22829128088385117,0.31086666228014365,-0.2276042406016599,2.6009562194312528,0.14483658048926837,-0.5562072945734238,1.486355749287792,4.432259380667763,-0.3160348969490162,0.8923926409127418,2.5792918852390194,-0.8650123589926522
3,375
Lipid homeostasis
7
28
2.590017
0.009597
Q9HCL2,Q8WTV0,P35610,O15260,P09455,Q96CP7,Q5BJF2
Processes and pathways
GO Biological process
msigdb_gobp
172,6,102,9,267,107,21
1413,285,2418,9,1959,267,2623,825,102,3298,797,1038,799,21,2520,1239,1082,6,107,926,608,703,172,1886,2950,3103,1946,584
0.08869434652356714,1.0945945877969334,-0.4053649182267038,4.069826366870343,-0.16915765752368028,1.1692883875750077,-0.5562072945734238,0.44662661518260455,2.092004590409298,-1.9465598176439003,0.47350891704813686,0.31086666228014365,0.47350891704813686,3.4373901045291917,-0.4654106405661174,0.2005724364337766,0.28343716336325137,4.432259380667763,2.046631135288513,0.39259560337501387,0.6330026427578571,0.5536355300185024,1.5580872461878,-0.11112230190969725,-0.8650123589926522,-1.1186374013991909,-0.14008827619228245,0.6592940398904245
3,375
Metallopeptidase activity
13
41
2.571149
0.010136
Q9NZ08,Q9UIQ6,Q10713,Q9BYT8,P50579,P42892,Q7Z2K6,Q7L5N1,P55786,O75844,Q5JRX3,O75976,O95630
Functions
GO Molecular function
msigdb_gomf
204,100,414,402,77,50,116,631,22,88,281,587,589
2148,2022,744,615,1787,88,587,589,1113,2269,1895,1539,1174,3039,2884,50,77,1552,950,22,414,281,3234,883,631,116,1460,1463,1138,1930,2136,1209,402,1305,2849,1937,812,1152,204,100,2018
-0.2569802644281954,-0.1983298434546702,0.5003038219140473,0.6066297150102449,-0.08226034641678645,2.2046220417723954,0.6330026427578571,0.6330026427578571,0.25591244186398043,-0.3160348969490162,-0.14008827619228245,0.03213471430384632,0.22829128088385117,-1.0228587054425817,-0.8025083410499405,2.622580671152067,2.2716465763795988,0.03213471430384632,0.36544472945786843,3.4171394805890736,0.8667959860819097,1.1195590959099642,-1.4765043166587404,0.41965586752605055,0.6066297150102449,1.9782122047843376,0.08869434652356714,0.08869434652356714,0.25591244186398043,-0.14008827619228245,-0.2276042406016599,0.22829128088385117,0.8923926409127418,0.17275463656922826,-0.74037215539053,-0.14008827619228245,0.47350891704813686,0.25591244186398043,1.4382450552811312,2.1146206568398127,-0.16915765752368028
3,375
Receptor
9
37
2.55978
0.010474
Q8WTV0,O15118,O15173,P20645,Q99720,Q14739,P30825,Q9NS69,Q14108
Functions
Protein Atlas Molecular function
protein_atlas_molecular_function
6,285,195,137,12,174,85,29,31
1157,2952,285,195,1848,2028,1113,2734,2372,2422,2423,2660,2105,869,1539,137,1658,85,3062,622,1914,31,174,1041,2557,344,6,1927,1516,3203,12,29,2081,3183,938,3145,3323
0.22829128088385117,-0.8964011979097756,1.0945945877969334,1.4382450552811312,-0.11112230190969725,-0.1983298434546702,0.25591244186398043,-0.6478655125716591,-0.3754892338100565,-0.4053649182267038,-0.4053649182267038,-0.5866649642761562,-0.2276042406016599,0.41965586752605055,0.03213471430384632,1.7935845599756126,-0.024850986633067236,2.2270083787382036,-1.0546965194844964,0.6066297150102449,-0.14008827619228245,3.1509596999717213,1.5342340098871912,0.31086666228014365,-0.49557962951464074,0.9940553151106681,4.432259380667763,-0.14008827619228245,0.060467414101225296,-1.3778800978198302,3.9144271277439557,3.2539898346567666,-0.1983298434546702,-1.3125536644868265,0.39259560337501387,-1.2152058878452634,-2.2221815908693094
3,375
Organic acid transmembrane transporter activity
9
23
2.549254
0.010795
P53007,Q9BQT8,Q9Y619,Q9H2D1,Q9UBX3,P30825,P08183,O95563,Q9H2J7
Functions
GO Molecular function
msigdb_gomf
162,490,475,81,144,85,53,616,546
2539,1709,1847,616,53,2373,85,1430,162,657,1280,2557,1747,1760,490,81,546,930,1884,144,2205,2904,475
-0.49557962951464074,-0.05350303097992167,-0.11112230190969725,0.6066297150102449,2.5792918852390194,-0.3754892338100565,2.2270083787382036,0.08869434652356714,1.5818838811891258,0.5801743268480191,0.17275463656922826,-0.49557962951464074,-0.05350303097992167,-0.05350303097992167,0.7636623002448963,2.2716465763795988,0.6855048182603979,0.39259560337501387,-0.11112230190969725,1.7235018312297918,-0.2569802644281954,-0.8025083410499405,0.7895593798784971
3,375
Neuron apoptotic process
11
55
2.548371
0.010823
P09601,O43813,P48507,Q13464,P05067,Q99720,P31751,Q96A26,P50897,Q99538,P06400
Processes and pathways
GO Biological process
msigdb_gobp
68,101,221,42,166,12,148,152,55,92,254
1948,101,1110,822,589,1850,358,3345,2266,2733,166,254,2158,1537,2103,68,1853,1657,1172,148,1903,948,1964,2111,221,3176,875,656,2043,55,2919,1665,1970,2169,2920,3230,599,1330,688,1387,42,2891,1976,1041,2446,1462,152,698,2006,92,12,3076,294,2495,3032
-0.16915765752368028,2.092004590409298,0.25591244186398043,0.44662661518260455,0.6330026427578571,-0.11112230190969725,0.9433672737733582,-2.7162642799123433,-0.3160348969490162,-0.6478655125716591,1.5580872461878,1.2187556408509548,-0.2569802644281954,0.03213471430384632,-0.2276042406016599,2.4703624293785205,-0.11112230190969725,-0.024850986633067236,0.22829128088385117,1.700034827064007,-0.14008827619228245,0.36544472945786843,-0.16915765752368028,-0.2276042406016599,1.3169237397506999,-1.3125536644868265,0.41965586752605055,0.5801743268480191,-0.1983298434546702,2.5792918852390194,-0.8337145938116572,-0.024850986633067236,-0.16915765752368028,-0.2569802644281954,-0.8337145938116572,-1.4765043166587404,0.6330026427578571,0.14483658048926837,0.5536355300185024,0.11681693759758847,2.857891489435327,-0.8025083410499405,-0.16915765752368028,0.31086666228014365,-0.4053649182267038,0.08869434652356714,1.676514037712598,0.5536355300185024,-0.16915765752368028,2.182190438903513,3.9144271277439557,-1.0546965194844964,1.0945945877969334,-0.43533889653030694,-0.9911098512078583
3,375
Biliary tract abnormality
15
29
2.545992
0.010897
O96028,P09601,P14174,Q10713,Q96J02,Q9NSD9,Q14739,Q9H0F7,P04062,Q9NZJ7,O43933,P50542,O43681,Q93008,Q14108
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
65,68,255,414,670,738,174,637,358,772,145,522,683,452,31
683,145,2027,65,2878,358,1420,68,255,1173,2624,2111,522,2167,1968,414,2180,1815,31,174,3240,452,670,637,738,772,934,1843,818
0.5536355300185024,1.700034827064007,-0.1983298434546702,2.4922302839791723,-0.8025083410499405,0.9433672737733582,0.08869434652356714,2.4703624293785205,1.2187556408509548,0.22829128088385117,-0.5562072945734238,-0.2276042406016599,0.7116358722612617,-0.2569802644281954,-0.16915765752368028,0.8667959860819097,-0.2569802644281954,-0.08226034641678645,3.1509596999717213,1.5342340098871912,-1.5095468498520557,0.8153801473078209,0.5801743268480191,0.6066297150102449,0.5270123572912739,0.5003038219140473,0.39259560337501387,-0.08226034641678645,0.47350891704813686
3,375
Abnormality of the amniotic fluid
25
89
2.543521
0.010974
P50570,O15047,P23786,P27635,Q9BXW9,Q7LGA3,P53007,Q14739,Q8TD19,Q6P3W7,Q92890,Q9UBM7,O60566,P51798,Q53EZ4,Q8IYB7,P21281,Q9UHX1,O75844,Q969X5,O15360,Q9BT22,P04062,Q70HW3,Q92766
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
503,499,20,158,292,289,162,174,298,297,439,57,431,180,314,450,446,349,88,232,477,365,358,242,382
940,499,477,1530,1223,1020,431,1480,88,2878,358,1790,3014,2506,2106,1540,446,907,20,748,158,2624,2860,3148,1429,991,1118,520,3308,503,2166,2167,180,162,1379,3041,2863,2170,2710,3163,2973,688,1811,1608,2434,174,2125,1819,1236,3047,314,1614,1747,297,2289,693,242,2344,289,2716,450,1996,298,382,439,964,232,1513,1685,2899,2563,365,701,2402,292,1696,738,1014,1700,57,349,3109,1522,2146,2363,2015,1946,856,2256
0.36544472945786843,0.7376880792986121,0.7636623002448963,0.03213471430384632,0.2005724364337766,0.31086666228014365,0.8411254163810149,0.060467414101225296,2.2046220417723954,-0.8025083410499405,0.9433672737733582,-0.08226034641678645,-0.9911098512078583,-0.4654106405661174,-0.2276042406016599,0.03213471430384632,0.8153801473078209,0.39259560337501387,3.457609530408841,0.5003038219140473,1.6056244017080097,-0.5562072945734238,-0.771394044942476,-1.2475690670035406,0.08869434652356714,0.33820212925301407,0.25591244186398043,0.7116358722612617,-2.0493327505938783,0.7376880792986121,-0.2569802644281954,-0.2569802644281954,1.5103236781354623,1.5818838811891258,0.11681693759758847,-1.0228587054425817,-0.771394044942476,-0.2569802644281954,-0.6172178657741221,-1.2800184510915182,-0.9278806773204062,0.5536355300185024,-0.08226034641678645,0.0036951455715587326,-0.4053649182267038,1.5342340098871912,-0.2276042406016599,-0.08226034641678645,0.2005724364337766,-1.0228587054425817,1.0444625558272569,0.0036951455715587326,-0.05350303097992167,1.0695626309218393,-0.3160348969490162,0.5536355300185024,1.2679658226874506,-0.34571237893882045,1.0945945877969334,-0.6172178657741221,0.8153801473078209,-0.16915765752368028,1.0695626309218393,0.91791615126421,0.8411254163810149,0.36544472945786843,1.292476019958997,0.060467414101225296,-0.024850986633067236,-0.8025083410499405,-0.49557962951464074,0.9433672737733582,0.5536355300185024,-0.3754892338100565,1.0945945877969334,-0.024850986633067236,0.5270123572912739,0.33820212925301407,-0.024850986633067236,2.5792918852390194,0.9940553151106681,-1.150739668468142,0.060467414101225296,-0.2276042406016599,-0.34571237893882045,-0.16915765752368028,-0.14008827619228245,0.44662661518260455,-0.28645733903368353
3,375
Inability to walk
11
92
2.542196
0.011016
O14949,O75503,Q99720,Q9C0D9,Q9BYI3,P12235,Q96RL7,Q96CU9,Q9NR77,P00846,P27635
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
128,98,12,109,86,54,58,27,61,156,158
1475,2657,128,1164,2987,1417,98,1848,3112,982,1956,2502,156,1537,867,2374,651,54,2880,905,2584,1115,685,158,789,1900,1901,2508,2624,2467,1428,2861,1963,167,2919,3321,1967,1806,951,995,1603,1865,2120,879,1815,1188,2890,1126,2516,1288,1819,1987,1293,1294,2058,2640,316,2348,2559,2895,1341,667,1571,3169,3002,730,2242,841,27,2982,453,1759,58,301,2562,3052,12,701,1764,86,109,1689,734,1146,61,1700,3171,2760,1703,1525,856,2417
0.060467414101225296,-0.5866649642761562,1.8400454612708395,0.22829128088385117,-0.9594503693142111,0.08869434652356714,2.1146206568398127,-0.11112230190969725,-1.1829292935550804,0.33820212925301407,-0.16915765752368028,-0.4654106405661174,1.6293092873800175,0.03213471430384632,0.41965586752605055,-0.3754892338100565,0.5801743268480191,2.5792918852390194,-0.8025083410499405,0.39259560337501387,-0.5258453497283577,0.25591244186398043,0.5536355300185024,1.6056244017080097,0.47350891704813686,-0.14008827619228245,-0.14008827619228245,-0.4654106405661174,-0.5562072945734238,-0.43533889653030694,0.08869434652356714,-0.771394044942476,-0.16915765752368028,1.5580872461878,-0.8337145938116572,-2.2221815908693094,-0.16915765752368028,-0.08226034641678645,0.36544472945786843,0.33820212925301407,0.0036951455715587326,-0.11112230190969725,-0.2276042406016599,0.41965586752605055,-0.08226034641678645,0.22829128088385117,-0.8025083410499405,0.25591244186398043,-0.4654106405661174,0.17275463656922826,-0.08226034641678645,-0.16915765752368028,0.17275463656922826,0.17275463656922826,-0.1983298434546702,-0.5562072945734238,1.0444625558272569,-0.34571237893882045,-0.49557962951464074,-0.8025083410499405,0.14483658048926837,0.5801743268480191,0.03213471430384632,-1.2800184510915182,-0.9594503693142111,0.5270123572912739,-0.28645733903368353,0.44662661518260455,3.315412158687853,-0.9278806773204062,0.8153801473078209,-0.05350303097992167,2.557587398973077,1.0695626309218393,-0.49557962951464074,-1.0228587054425817,3.9144271277439557,0.5536355300185024,-0.05350303097992167,2.2270083787382036,2.0238730257815676,-0.024850986633067236,0.5270123572912739,0.25591244186398043,2.5358424878703127,-0.024850986633067236,-1.2800184510915182,-0.6478655125716591,-0.024850986633067236,0.060467414101225296,0.44662661518260455,-0.3754892338100565
3,375
Vacuolar lumen
16
63
2.539069
0.011115
P11117,O14773,Q8NHP8,Q9UM22,P04066,Q9BRF8,P10619,P10253,P16278,P04062,P50897,P38435,Q9UMR5,Q99538,Q8IV08,Q14108
Localization
GO Cellular component
msigdb_gocc
286,188,99,39,266,139,196,231,207,358,55,245,122,92,94,31
1708,975,3187,188,683,1536,358,266,432,684,2953,1026,1420,3218,2267,650,231,196,286,2314,1422,2856,207,2034,1171,2379,2110,245,3264,1493,2277,55,1119,1180,2626,480,2327,1231,3298,1072,1438,2283,2051,2890,31,832,94,2944,99,1204,1928,1686,384,92,139,1210,732,3337,612,772,39,122,1705
-0.05350303097992167,0.33820212925301407,-1.3451743358044173,1.4623297140439213,0.5536355300185024,0.03213471430384632,0.9433672737733582,1.1692883875750077,0.8411254163810149,0.5536355300185024,-0.8964011979097756,0.31086666228014365,0.08869434652356714,-1.4435454454021128,-0.3160348969490162,0.5801743268480191,1.292476019958997,1.4382450552811312,1.0945945877969334,-0.34571237893882045,0.08869434652356714,-0.771394044942476,1.3898977585599475,-0.1983298434546702,0.22829128088385117,-0.3754892338100565,-0.2276042406016599,1.24339256161293,-1.6425467075224687,0.060467414101225296,-0.3160348969490162,2.5792918852390194,0.25591244186398043,0.22829128088385117,-0.5562072945734238,0.7636623002448963,-0.34571237893882045,0.2005724364337766,-1.9465598176439003,0.28343716336325137,0.08869434652356714,-0.3160348969490162,-0.1983298434546702,-0.8025083410499405,3.1509596999717213,0.44662661518260455,2.159713234494772,-0.8650123589926522,2.1146206568398127,0.22829128088385117,-0.14008827619228245,-0.024850986633067236,0.91791615126421,2.182190438903513,1.7469154961042097,0.22829128088385117,0.5270123572912739,-2.502718876001027,0.6330026427578571,0.5003038219140473,2.9423357816117885,1.9093538048745637,-0.024850986633067236
3,375
Increased bone mineral density
9
26
2.537163
0.011175
Q13126,P54802,P48651,Q14739,Q9Y4P3,P04062,Q15392,P51798,Q14108
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
1,480,141,174,408,358,51,180,31
1166,2878,358,2546,747,1490,1270,558,141,180,480,2327,2887,1741,1,2746,31,1869,174,1562,51,957,3281,2251,1642,408
0.22829128088385117,-0.8025083410499405,0.9433672737733582,-0.49557962951464074,0.5003038219140473,0.060467414101225296,0.17275463656922826,0.6592940398904245,1.7235018312297918,1.5103236781354623,0.7636623002448963,-0.34571237893882045,-0.8025083410499405,-0.05350303097992167,5.487805323059808,-0.6478655125716591,3.1509596999717213,-0.11112230190969725,1.5342340098871912,0.03213471430384632,2.6009562194312528,0.36544472945786843,-1.7431583887779178,-0.28645733903368353,0.0036951455715587326,0.8923926409127418
3,375