term
stringlengths 2
121
| overlap
int64 6
281
| setsize
int64 7
499
| score
float64 1.96
10.6
| pval
float64 0
0.05
| edge
stringlengths 41
1.97k
| type
stringclasses 5
values | subtype
stringclasses 24
values | subtype_key
stringclasses 24
values | edge_idxs
stringlengths 11
1.17k
| ann_idxs
stringlengths 19
2.31k
| ann_vals
stringlengths 124
9.94k
| sig_size
int64 2.2k
3.73k
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Endopeptidase activity
| 24
| 60
| 3.055885
| 0.002244
|
Q9BXS4,P28070,P07384,P67812,Q92542,Q5JRX3,O14773,P28072,Q99538,P28074,P52888,O43464,Q4J6C6,O75844,Q10713,P49721,P20618,P49720,Q96K76,P42892,Q16740,Q8TCT9,Q5TDH0,Q9NZ08
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
397,138,394,13,400,412,25,179,184,687,441,590,732,88,608,99,239,244,763,118,376,514,634,127
|
25,590,1574,2219,88,394,1828,1703,3268,239,754,2720,138,179,687,1631,2520,2230,2489,118,1193,1375,244,99,2839,441,1483,810,13,608,1302,2497,2616,376,732,412,634,1846,2462,514,400,1273,851,2507,1392,763,1357,2385,1134,184,2115,1726,397,1080,127,2776,1142,1087,3131,1659
|
3.190224570239214,0.6667202646970376,-0.0634896107921604,-0.37587289727828466,2.5201665300557425,1.0011735038559333,-0.18558195150973228,-0.12407556372432456,-1.4833391917688719,1.445839319599628,0.47910021734806124,-0.6440760551569396,2.0415749265642926,1.7809092990421234,0.5483849475613088,-0.0835841298387108,-0.5302135415922944,-0.37587289727828466,-0.5078096934092219,2.186879575171654,0.15115574181980668,0.055014368762545285,1.4323066040977575,2.4195100841990267,-0.7374490318787568,0.9085950944992713,-0.0038005361770060086,0.42631322556594947,3.4306920800070304,0.6500364914113959,0.09374950248621658,-0.5078096934092219,-0.5753864237832664,1.046618985345816,0.5138974074088837,0.9705669749994547,0.6164499083295459,-0.18558195150973228,-0.4855260677859258,0.7815125855528189,0.9859014847349855,0.11297700392516687,0.3907205059965324,-0.5078096934092219,0.055014368762545285,0.47910021734806124,0.07442888489169129,-0.44131505481374056,0.18897117543040606,1.7685881177452407,-0.31145474882693824,-0.12407556372432456,1.0011735038559333,0.2264292404709339,2.1094015983677914,-0.6672254158451334,0.18897117543040606,0.2264292404709339,-1.0814780591807345,-0.0835841298387108
| 3,376
|
Ragged red muscle fibers
| 6
| 18
| 3.054574
| 0.002254
|
Q9Y5P6,P00846,Q9H2D1,Q70HW3,P03886,P12235
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
227,7,42,113,24,154
|
2303,1089,1372,267,7,24,154,2450,2272,1069,1342,113,2701,1241,2983,42,1613,227
|
-0.41938548886236693,0.2077445134366247,0.055014368762545285,1.3500342456184196,3.576464581247993,3.214321038100156,1.9607270744213334,-0.4855260677859258,-0.3975717877794668,0.2264292404709339,0.07442888489169129,2.262642140545865,-0.6210539026805592,0.1321121623528798,-0.8571497916635558,2.990550171469064,-0.0634896107921604,1.4994697838784592
| 3,376
|
Alzheimers disease and mirna effects
| 19
| 88
| 3.046421
| 0.002316
|
P25787,P21796,P28070,P45880,P07384,P05067,Q96GC9,Q92542,P12235,O95197,P16615,P28072,P49841,P49721,Q9Y277,Q9NQC3,P31751,P20618,P49720
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
263,8,138,11,394,143,144,400,154,30,302,179,330,99,231,106,232,239,244
|
2440,2808,1285,1738,2301,1330,30,2755,143,1118,2051,394,792,448,154,497,1703,302,3268,1628,1830,2834,1094,239,8,543,263,2090,2720,1222,1880,138,179,687,1974,2994,232,1257,1976,2721,1754,1224,2489,1296,11,1032,1582,1299,244,99,330,1481,2788,810,1714,1523,1636,813,892,1381,1937,1036,1198,845,3104,1759,1842,1232,2693,1941,580,820,400,1458,144,903,1134,2168,2207,3125,1359,1693,958,106,673,1545,231,1144
|
-0.4855260677859258,-0.7139106589140215,0.09374950248621658,-0.14447423395217424,-0.41938548886236693,0.07442888489169129,3.108547336875158,-0.6672254158451334,2.018667073067943,0.18897117543040606,-0.2902048261296045,1.0011735038559333,0.4439885391534624,0.8929413902574874,1.9607270744213334,0.7976328933322394,-0.12407556372432456,1.2230433462408152,-1.4833391917688719,-0.0835841298387108,-0.18558195150973228,-0.7374490318787568,0.2077445134366247,1.445839319599628,3.555036482266552,0.7327378977030797,1.3776655599934584,-0.31145474882693824,-0.6440760551569396,0.1321121623528798,-0.20629282062173515,2.0415749265642926,1.7809092990421234,0.5483849475613088,-0.2480332200865538,-0.8815009988157699,1.4727539894057913,0.11297700392516687,-0.2480332200865538,-0.6440760551569396,-0.14447423395217424,0.1321121623528798,-0.5078096934092219,0.09374950248621658,3.4381474194828905,0.2450260771368476,-0.0634896107921604,0.09374950248621658,1.4323066040977575,2.4195100841990267,1.1505511630774563,-0.0038005361770060086,-0.6905032048336213,0.42631322556594947,-0.12407556372432456,-0.023598660010764588,-0.0835841298387108,0.42631322556594947,0.3548007225100377,0.055014368762545285,-0.22710959688583782,0.2450260771368476,0.15115574181980668,0.3907205059965324,-1.0306021517672246,-0.14447423395217424,-0.18558195150973228,0.1321121623528798,-0.6210539026805592,-0.22710959688583782,0.6833317551050844,0.42631322556594947,0.9859014847349855,0.015900464346774338,2.018667073067943,0.3548007225100377,0.18897117543040606,-0.33281539857511017,-0.354287776657499,-1.0559648852353496,0.07442888489169129,-0.10377915671823269,0.3185486441921405,2.357634147809756,0.5825675708995396,-0.023598660010764588,1.486136587048457,0.18897117543040606
| 3,376
|
Dementia
| 21
| 64
| 3.044715
| 0.002329
|
O43681,O76024,P06865,P00846,P00403,P05067,Q96RL7,P35670,P03886,O15118,Q14108,Q9Y487,O96008,Q9NZJ7,O60313,Q9UBB4,P35637,P07602,P04062,P17900,Q13510
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
506,507,262,7,267,143,146,526,24,157,37,423,557,444,329,600,460,333,90,353,111
|
826,157,590,506,329,2400,507,557,267,7,24,90,1623,143,262,333,2261,2855,353,1926,918,1334,2857,2450,1932,460,526,1411,1798,1412,1295,3292,1069,2407,2148,812,708,2528,3071,2060,897,111,37,1040,1588,1686,1526,2109,2113,2426,1853,146,1241,2803,2429,444,600,2778,1051,767,824,1735,423,2392
|
0.4085574264207841,1.9136707952245202,0.6667202646970376,0.7815125855528189,1.1505511630774563,-0.4633615537366067,0.7815125855528189,0.7163400404236764,1.3500342456184196,3.576464581247993,3.214321038100156,2.4902865084460193,-0.0835841298387108,2.018667073067943,1.3776655599934584,1.135880610204166,-0.3975717877794668,-0.7611195948253038,1.1063642295621396,-0.22710959688583782,0.3367165517731276,0.07442888489169129,-0.7611195948253038,-0.4855260677859258,-0.22710959688583782,0.8614378522891492,0.7490655969974919,0.03550516234149863,-0.16497606147263494,0.03550516234149863,0.09374950248621658,-1.6549680395922322,0.2264292404709339,-0.4633615537366067,-0.33281539857511017,0.42631322556594947,0.5311795854762361,-0.5302135415922944,-0.980321919952045,-0.2902048261296045,0.3548007225100377,2.315743939212719,3.050094664845848,0.2450260771368476,-0.0634896107921604,-0.10377915671823269,-0.023598660010764588,-0.31145474882693824,-0.31145474882693824,-0.4633615537366067,-0.18558195150973228,2.0071561264974758,0.1321121623528798,-0.6905032048336213,-0.4633615537366067,0.9085950944992713,0.6667202646970376,-0.6672254158451334,0.2450260771368476,0.47910021734806124,0.42631322556594947,-0.12407556372432456,0.9551695312607196,-0.44131505481374056
| 3,376
|
Apical plasma membrane
| 15
| 46
| 3.03466
| 0.002408
|
P11166,O43865,P30825,O75955,P53985,O00165,P61421,P04083,Q9Y4G8,P55011,P08195,Q8IZT6,P08183,Q86UE4,Q9NV70
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
408,386,56,343,199,602,456,393,373,411,525,27,216,286,553
|
602,1663,1737,1699,1664,1062,386,770,343,393,628,1671,216,525,985,1442,408,1748,1878,3031,829,1123,1630,56,1977,1411,1223,1798,2722,199,1337,411,456,1038,1303,1039,2974,1525,286,27,2115,2070,553,1658,373,861
|
0.6500364914113959,-0.10377915671823269,-0.14447423395217424,-0.12407556372432456,-0.10377915671823269,0.2264292404709339,1.0163834713233377,0.4615839958458578,1.1211517662256676,1.0011735038559333,0.6164499083295459,-0.10377915671823269,1.5391760995751391,0.7490655969974919,0.28195892039051096,0.015900464346774338,0.9705669749994547,-0.14447423395217424,-0.20629282062173515,-0.9306254080954044,0.4085574264207841,0.18897117543040606,-0.0835841298387108,2.7958932046881895,-0.2480332200865538,0.03550516234149863,0.1321121623528798,-0.16497606147263494,-0.6440760551569396,1.6429624336734927,0.07442888489169129,0.9705669749994547,0.8772224665898438,0.2450260771368476,0.09374950248621658,0.2450260771368476,-0.8571497916635558,-0.023598660010764588,1.3081910804853814,3.1659423425394335,-0.31145474882693824,-0.2902048261296045,0.7327378977030797,-0.0835841298387108,1.0616453881949772,0.3907205059965324
| 3,376
|
Peptidase activity
| 31
| 113
| 3.028488
| 0.002458
|
Q9BXS4,P28070,P07384,P67812,Q92542,P55786,Q15005,O14773,Q5JRX3,O75976,P02786,Q9UIQ6,Q96FZ2,P28072,Q9HB40,Q99538,P52888,P10619,Q9H3G5,O75844,Q9BT78,P49721,P42785,Q92890,Q96BN8,P20618,P49720,P42892,Q16740,Q8TCT9,Q9NZ08
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
397,138,394,13,400,145,280,25,412,406,407,309,308,179,55,184,441,68,73,88,349,99,101,487,488,239,244,118,376,514,127
|
1505,1285,25,827,590,1574,2219,88,406,2442,2679,725,407,394,1406,68,2605,1828,1703,3268,239,754,2720,138,179,687,3243,1631,2520,1223,2230,2489,101,118,1193,1375,244,99,921,1481,2839,441,1801,1483,145,810,13,2370,1099,608,2326,1302,2497,2616,280,376,732,2413,412,634,2795,1993,1846,2197,2286,1591,595,1103,2462,745,1527,514,400,1273,785,487,851,2507,1392,1274,488,1597,308,763,2206,1357,2385,1134,2803,184,2115,1726,349,397,1080,73,2172,1393,515,55,1109,1606,1569,2345,1781,127,2776,309,1142,1087,3131,1659,1916
|
-0.023598660010764588,0.09374950248621658,3.190224570239214,0.4085574264207841,0.6667202646970376,-0.0634896107921604,-0.37587289727828466,2.5201665300557425,0.9705669749994547,-0.4855260677859258,-0.6210539026805592,0.5138974074088837,0.9705669749994547,1.0011735038559333,0.03550516234149863,2.67513802823974,-0.5753864237832664,-0.18558195150973228,-0.12407556372432456,-1.4833391917688719,1.445839319599628,0.47910021734806124,-0.6440760551569396,2.0415749265642926,1.7809092990421234,0.5483849475613088,-1.3725120489511942,-0.0835841298387108,-0.5302135415922944,0.1321121623528798,-0.37587289727828466,-0.5078096934092219,2.4092761099767857,2.186879575171654,0.15115574181980668,0.055014368762545285,1.4323066040977575,2.4195100841990267,0.3367165517731276,-0.0038005361770060086,-0.7374490318787568,0.9085950944992713,-0.16497606147263494,-0.0038005361770060086,2.0071561264974758,0.42631322556594947,3.4306920800070304,-0.44131505481374056,0.2077445134366247,0.6500364914113959,-0.41938548886236693,0.09374950248621658,-0.5078096934092219,-0.5753864237832664,1.322192093055503,1.046618985345816,0.5138974074088837,-0.4633615537366067,0.9705669749994547,0.6164499083295459,-0.6905032048336213,-0.2480332200865538,-0.18558195150973228,-0.354287776657499,-0.3975717877794668,-0.0634896107921604,0.6667202646970376,0.2077445134366247,-0.4855260677859258,0.4965378185069035,-0.023598660010764588,0.7815125855528189,0.9859014847349855,0.11297700392516687,0.4615839958458578,0.8296696426224738,0.3907205059965324,-0.5078096934092219,0.055014368762545285,0.11297700392516687,0.8296696426224738,-0.0634896107921604,1.2230433462408152,0.47910021734806124,-0.354287776657499,0.07442888489169129,-0.44131505481374056,0.18897117543040606,-0.6905032048336213,1.7685881177452407,-0.31145474882693824,-0.12407556372432456,1.1211517662256676,1.0011735038559333,0.2264292404709339,2.617870951389883,-0.33281539857511017,0.055014368762545285,0.7815125855528189,2.804999778473982,0.2077445134366247,-0.0634896107921604,-0.043494737915892735,-0.41938548886236693,-0.14447423395217424,2.1094015983677914,-0.6672254158451334,1.2230433462408152,0.18897117543040606,0.2264292404709339,-1.0814780591807345,-0.0835841298387108,-0.20629282062173515
| 3,376
|
Transport vesicle
| 36
| 94
| 3.024593
| 0.00249
|
P10321,O15126,O76024,Q15363,O15027,P05067,Q92542,P04439,Q7L0J3,P50897,Q99523,O14579,P11717,O15260,O60499,Q15836,Q9Y3B3,P0DP25,Q9GZY8,O43752,O95249,Q9BVK6,P61421,Q9H0U4,O00461,Q9BT78,Q96A57,Q13190,Q15436,P49755,Q9NR31,P11279,P20337,Q9HD26,O43760,P20645
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
509,505,507,5,627,143,400,273,281,22,668,657,542,39,41,436,57,448,327,200,201,332,456,599,80,349,347,474,486,485,625,356,492,501,114,374
|
826,80,657,3133,627,505,39,1329,1740,1920,200,114,2359,41,863,1669,2303,2131,507,1514,201,2221,2482,2754,273,143,1876,2966,448,509,356,542,829,492,2403,2449,374,2092,2185,1191,1798,1836,679,485,22,2318,2056,2523,988,2813,2320,2057,2611,1484,797,1677,456,2925,3227,1229,2100,1159,474,1039,3041,3163,1585,2330,2900,5,486,3072,436,1590,281,871,400,851,347,668,349,332,327,599,501,625,982,2076,2779,1212,939,57,1026,1368
|
0.4085574264207841,2.5693783360444082,0.5825675708995396,-1.1071432230243936,0.6164499083295459,0.7815125855528189,3.016205187599177,0.07442888489169129,-0.14447423395217424,-0.22710959688583782,1.630152502007486,2.2411669014570372,-0.44131505481374056,3.007676347681497,0.372801821409757,-0.10377915671823269,-0.41938548886236693,-0.33281539857511017,0.7815125855528189,-0.023598660010764588,1.630152502007486,-0.37587289727828466,-0.5078096934092219,-0.6672254158451334,1.3361396976874031,2.018667073067943,-0.20629282062173515,-0.8571497916635558,0.8929413902574874,0.7815125855528189,1.0915175946894244,0.7327378977030797,0.4085574264207841,0.8136850803085195,-0.4633615537366067,-0.4855260677859258,1.046618985345816,-0.31145474882693824,-0.354287776657499,0.15115574181980668,-0.16497606147263494,-0.18558195150973228,0.565514082039327,0.8296696426224738,3.2302833584863713,-0.41938548886236693,-0.2902048261296045,-0.5302135415922944,0.28195892039051096,-0.7139106589140215,-0.41938548886236693,-0.2902048261296045,-0.5753864237832664,-0.0038005361770060086,0.4439885391534624,-0.10377915671823269,0.8772224665898438,-0.808862463451572,-1.3181298258671186,0.1321121623528798,-0.31145474882693824,0.17010849742073567,0.8455870712937495,0.2450260771368476,-0.9306254080954044,-1.1589358324480967,-0.0634896107921604,-0.41938548886236693,-0.784923636467135,3.708771690562757,0.8296696426224738,-0.980321919952045,0.9241840457318883,-0.0634896107921604,1.322192093055503,0.372801821409757,0.9859014847349855,0.3907205059965324,1.1211517662256676,0.5825675708995396,1.1211517662256676,1.1505511630774563,1.1651638225306005,0.6667202646970376,0.7976328933322394,0.6332798897464621,0.3002963271667747,-0.2902048261296045,-0.6672254158451334,0.15115574181980668,0.3367165517731276,2.786761095827931,0.2635357357357556,0.07442888489169129
| 3,376
|
Monovalent inorganic cation homeostasis
| 11
| 28
| 3.010115
| 0.002611
|
Q15904,Q9Y487,O75503,Q8N511,Q9Y5X3,P61421,Q9HC07,P55011,P50897,Q92544,Q93050
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
295,423,137,40,566,456,112,411,22,500,188
|
137,770,1373,628,1671,1220,1187,1222,1974,22,2318,1337,411,456,1758,295,40,500,188,1565,1906,112,1212,911,423,566,2550,861
|
2.0415749265642926,0.4615839958458578,0.055014368762545285,0.6164499083295459,-0.10377915671823269,0.1321121623528798,0.15115574181980668,0.1321121623528798,-0.2480332200865538,3.2302833584863713,-0.41938548886236693,0.07442888489169129,0.9705669749994547,0.8772224665898438,-0.14447423395217424,1.251645809202598,3.016205187599177,0.7976328933322394,1.7313649796578738,-0.043494737915892735,-0.20629282062173515,2.294602822374333,0.15115574181980668,0.3548007225100377,0.9551695312607196,0.7163400404236764,-0.5302135415922944,0.3907205059965324
| 3,376
|
Secretory granule membrane
| 22
| 73
| 3.007159
| 0.002637
|
P35613,P10321,O15126,O60645,Q15363,Q92542,O00264,P30519,P27105,O15260,P10253,Q9NZJ7,Q93050,Q07065,Q969Q5,P07602,Q8NF37,P42785,P49755,P11279,Q9NQX7,O15121
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
256,509,505,387,5,400,277,33,163,39,182,444,188,321,69,333,464,101,485,356,105,123
|
2636,277,123,505,39,1062,1968,387,646,1116,2400,770,2915,1874,333,182,509,356,542,3208,659,917,2449,163,33,1445,1520,256,1192,101,1885,485,2147,2318,988,2813,1484,797,1677,2764,3102,1804,1340,1486,321,621,2688,1039,1807,2374,1525,5,743,3294,1346,1812,464,1352,400,188,69,3091,1726,716,3301,2070,105,444,2435,2780,1179,2081,1009
|
-0.5981577547393172,1.322192093055503,2.1428207883227306,0.7815125855528189,3.016205187599177,0.2264292404709339,-0.2480332200865538,1.0163834713233377,0.5995459898347874,0.18897117543040606,-0.4633615537366067,0.4615839958458578,-0.808862463451572,-0.20629282062173515,1.135880610204166,1.7685881177452407,0.7815125855528189,1.0915175946894244,0.7327378977030797,-1.2644156881924795,0.5825675708995396,0.3367165517731276,-0.4855260677859258,1.8539458215110518,3.083627658114699,0.015900464346774338,-0.023598660010764588,1.3914030126962775,0.15115574181980668,2.4092761099767857,-0.20629282062173515,0.8296696426224738,-0.33281539857511017,-0.41938548886236693,0.28195892039051096,-0.7139106589140215,-0.0038005361770060086,0.4439885391534624,-0.10377915671823269,-0.6672254158451334,-1.0306021517672246,-0.16497606147263494,0.07442888489169129,-0.0038005361770060086,1.179718982402758,0.6332798897464621,-0.6210539026805592,0.2450260771368476,-0.16497606147263494,-0.44131505481374056,-0.023598660010764588,3.708771690562757,0.4965378185069035,-1.6549680395922322,0.07442888489169129,-0.16497606147263494,0.8614378522891492,0.07442888489169129,0.9859014847349855,1.7313649796578738,2.67513802823974,-1.0053883317133208,-0.12407556372432456,0.5311795854762361,-1.7136796782151344,-0.2902048261296045,2.3783860185520687,0.9085950944992713,-0.4633615537366067,-0.6672254158451334,0.17010849742073567,-0.2902048261296045,0.28195892039051096
| 3,376
|
Membrane lipid catabolic process
| 8
| 11
| 3.003765
| 0.002667
|
P17900,P04066,P06865,O95470,Q13510,P50897,P06280,P04062
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
353,291,262,265,111,22,310,90
|
265,90,291,310,262,1185,353,22,111,437,1173
|
1.3638760848112592,2.4902865084460193,1.2941363054249848,1.208658359818944,1.3776655599934584,0.15115574181980668,1.1063642295621396,3.2302833584863713,2.315743939212719,0.9241840457318883,0.17010849742073567
| 3,376
|
Protein targeting to membrane
| 17
| 36
| 2.999267
| 0.002706
|
O43681,A5D8V6,P43307,P27105,Q9GZY8,Q7L5D6,P31751,P49458,P46379,Q8N3F8,Q15629,Q9H9H4,O60725,P50542,Q99442,O00560,Q15041
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
506,379,34,163,327,521,232,493,140,275,50,415,126,382,476,446,570
|
379,1866,446,506,703,126,2753,2887,163,2186,232,2312,591,34,140,493,382,3069,2020,2568,1381,2530,570,50,521,1950,275,476,327,1210,415,806,719,983,1212,1864
|
1.0315318217278158,-0.20629282062173515,0.8929413902574874,0.7815125855528189,0.5311795854762361,2.1094015983677914,-0.6672254158451334,-0.784923636467135,1.8539458215110518,-0.354287776657499,1.4727539894057913,-0.41938548886236693,0.6667202646970376,3.083627658114699,2.030139933980146,0.8136850803085195,1.0315318217278158,-0.980321919952045,-0.26906464190792506,-0.552738738110152,0.055014368762545285,-0.5302135415922944,0.6998715023470454,2.8946877773816957,0.7653236556388097,-0.22710959688583782,1.3361396976874031,0.8455870712937495,1.1651638225306005,0.15115574181980668,0.9705669749994547,0.4439885391534624,0.5311795854762361,0.3002963271667747,0.15115574181980668,-0.18558195150973228
| 3,376
|
Rac2 gtpase cycle
| 15
| 36
| 2.997357
| 0.002723
|
P50402,Q7L576,O15173,Q8IZP0,P49257,Q14739,Q8TAA9,Q13505,P42167,P42166,Q15836,Q68EM7,Q9Y512,Q86XL3,P02786
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
417,418,72,710,679,428,203,76,484,631,436,413,416,92,407
|
72,2050,407,1796,1746,631,484,1885,679,417,2318,1448,2235,1806,741,1489,76,2190,428,436,1810,413,1812,418,92,928,710,203,2737,1728,1362,1695,1282,1008,1143,416
|
2.637070673082067,-0.2902048261296045,0.9705669749994547,-0.16497606147263494,-0.14447423395217424,0.6164499083295459,0.8296696426224738,-0.20629282062173515,0.565514082039327,0.9551695312607196,-0.41938548886236693,0.015900464346774338,-0.37587289727828466,-0.16497606147263494,0.4965378185069035,-0.0038005361770060086,2.598559042970186,-0.354287776657499,0.9397087056445106,0.9241840457318883,-0.16497606147263494,0.9705669749994547,-0.16497606147263494,0.9551695312607196,2.480266763739973,0.3367165517731276,0.5311795854762361,1.6172964774478464,-0.6440760551569396,-0.12407556372432456,0.07442888489169129,-0.10377915671823269,0.11297700392516687,0.28195892039051096,0.18897117543040606,0.9705669749994547
| 3,376
|
Glycosphingolipid metabolic process
| 7
| 10
| 2.987929
| 0.002809
|
Q16739,Q99805,P06865,Q9NZD2,P06280,P04062,P16278
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
64,196,262,210,310,90,93
|
90,310,262,1185,93,353,1303,64,196,210
|
2.4902865084460193,1.208658359818944,1.3776655599934584,0.15115574181980668,2.470216891564265,1.1063642295621396,0.09374950248621658,2.7127698952516086,1.6684451556620152,1.56540566205142
| 3,376
|
Abnormal retinal vascular morphology
| 16
| 51
| 2.983408
| 0.002851
|
P17900,P10619,P06865,P00846,Q9C0D9,Q13510,P04439,P38435,Q9Y4P3,P07602,O75306,P03886,Q9NZJ7,P35250,P16278,P21964
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
353,68,262,7,221,111,273,148,276,333,367,24,444,315,93,409
|
1662,1398,1510,2398,2359,367,2752,3016,2853,7,24,273,262,333,1185,2787,68,1331,2264,93,353,2089,918,409,2450,1976,315,1706,2365,148,3098,2453,2057,3054,1158,111,3201,973,758,2197,932,712,2506,487,1566,1500,221,1210,444,2988,276
|
-0.10377915671823269,0.03550516234149863,-0.023598660010764588,-0.4633615537366067,-0.44131505481374056,1.0616453881949772,-0.6672254158451334,-0.9059924038468624,-0.7611195948253038,3.576464581247993,3.214321038100156,1.3361396976874031,1.3776655599934584,1.135880610204166,0.15115574181980668,-0.6905032048336213,2.67513802823974,0.07442888489169129,-0.3975717877794668,2.470216891564265,1.1063642295621396,-0.31145474882693824,0.3367165517731276,0.9705669749994547,-0.4855260677859258,-0.2480332200865538,1.1942170327352566,-0.12407556372432456,-0.44131505481374056,1.9956068751611455,-1.0306021517672246,-0.4855260677859258,-0.2902048261296045,-0.9554014328962437,0.17010849742073567,2.315743939212719,-1.2378047400733483,0.3002963271667747,0.47910021734806124,-0.354287776657499,0.3367165517731276,0.5311795854762361,-0.5078096934092219,0.8296696426224738,-0.043494737915892735,-0.0038005361770060086,1.5259892299575761,0.15115574181980668,0.9085950944992713,-0.8571497916635558,1.3361396976874031
| 3,376
|
Endoplasmic reticulum golgi intermediate compartment
| 14
| 51
| 2.983122
| 0.002853
|
Q9Y282,P80303,Q15363,Q15904,Q8N511,O15260,Q9BVK6,O95070,Q96GC9,Q8IUR0,Q969X5,Q02818,Q9Y3B3,Q10472
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
97,4,5,295,40,39,332,204,144,307,339,242,57,285
|
914,39,1740,2131,204,1972,1029,3033,2140,2921,679,485,2610,1154,2813,1887,1711,4,242,334,1841,285,831,474,1718,2932,5,295,2460,307,734,40,1354,2465,1904,339,144,1318,936,332,1361,599,3281,2076,1212,97,615,57,1026,3364,1368
|
0.3367165517731276,3.016205187599177,-0.14447423395217424,-0.33281539857511017,1.6043940725091548,-0.2480332200865538,0.2450260771368476,-0.9306254080954044,-0.33281539857511017,-0.808862463451572,0.565514082039327,0.8296696426224738,-0.5753864237832664,0.17010849742073567,-0.7139106589140215,-0.20629282062173515,-0.12407556372432456,3.8158495588954837,1.445839319599628,1.135880610204166,-0.18558195150973228,1.3081910804853814,0.4085574264207841,0.8455870712937495,-0.12407556372432456,-0.808862463451572,3.708771690562757,1.251645809202598,-0.4855260677859258,1.2230433462408152,0.5138974074088837,3.016205187599177,0.07442888489169129,-0.4855260677859258,-0.20629282062173515,1.135880610204166,2.018667073067943,0.09374950248621658,0.3367165517731276,1.1505511630774563,0.07442888489169129,0.6667202646970376,-1.5398144784516654,-0.2902048261296045,0.15115574181980668,2.4398849348313916,0.6500364914113959,2.786761095827931,0.2635357357357556,-3.8041340926168594,0.07442888489169129
| 3,376
|
Bulbar signs
| 7
| 12
| 2.974477
| 0.002935
|
Q99720,P00846,P35637,P07602,P03886,Q9NZJ7,P04062
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
96,7,460,333,24,444,90
|
506,7,24,90,1625,333,460,1295,1496,96,444,1054
|
0.7815125855528189,3.576464581247993,3.214321038100156,2.4902865084460193,-0.0835841298387108,1.135880610204166,0.8614378522891492,0.09374950248621658,-0.0038005361770060086,2.4398849348313916,0.9085950944992713,0.2450260771368476
| 3,376
|
Abnormality of pulmonary circulation
| 8
| 27
| 2.949282
| 0.003185
|
Q8IZA0,Q14108,P04062,P00403,O96000,P03886,O75844,Q9NZ08
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
164,37,90,267,272,24,88,127
|
1326,2220,88,1515,272,267,2306,24,90,3135,793,3097,2228,1884,1299,311,1015,2494,37,2532,1561,780,164,1906,2006,127,2392
|
0.07442888489169129,-0.37587289727828466,2.5201665300557425,-0.023598660010764588,1.3361396976874031,1.3500342456184196,-0.41938548886236693,3.214321038100156,2.4902865084460193,-1.1071432230243936,0.4439885391534624,-1.0306021517672246,-0.37587289727828466,-0.20629282062173515,0.09374950248621658,1.208658359818944,0.2635357357357556,-0.5078096934092219,3.050094664845848,-0.5302135415922944,-0.043494737915892735,0.4615839958458578,1.8539458215110518,-0.20629282062173515,-0.2480332200865538,2.1094015983677914,-0.44131505481374056
| 3,376
|
Alzheimers disease
| 18
| 86
| 2.94676
| 0.003211
|
P49721,Q9Y277,P25787,P21796,Q9NQC3,P45880,P28070,P31751,P49841,P05067,P07384,Q92542,P20618,P16615,P49720,P28072,P12235,O95197
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
99,231,263,8,106,11,138,232,330,143,394,400,239,302,244,179,154,30
|
2440,2808,1285,1738,2301,1330,30,2755,143,1118,2051,394,792,448,154,497,1703,302,3268,1628,1830,2834,1094,239,8,543,263,2090,2720,1222,1880,138,179,687,1974,2994,232,1257,1976,2721,1754,1224,2489,1296,11,1032,1582,1299,244,99,330,1481,2788,810,1714,1523,1636,813,892,1381,1937,1036,1198,845,3104,1759,1842,1232,2693,1941,580,820,400,1458,1134,2168,2207,3125,1359,1693,958,106,673,1545,231,1144
|
-0.4855260677859258,-0.7139106589140215,0.09374950248621658,-0.14447423395217424,-0.41938548886236693,0.07442888489169129,3.108547336875158,-0.6672254158451334,2.018667073067943,0.18897117543040606,-0.2902048261296045,1.0011735038559333,0.4439885391534624,0.8929413902574874,1.9607270744213334,0.7976328933322394,-0.12407556372432456,1.2230433462408152,-1.4833391917688719,-0.0835841298387108,-0.18558195150973228,-0.7374490318787568,0.2077445134366247,1.445839319599628,3.555036482266552,0.7327378977030797,1.3776655599934584,-0.31145474882693824,-0.6440760551569396,0.1321121623528798,-0.20629282062173515,2.0415749265642926,1.7809092990421234,0.5483849475613088,-0.2480332200865538,-0.8815009988157699,1.4727539894057913,0.11297700392516687,-0.2480332200865538,-0.6440760551569396,-0.14447423395217424,0.1321121623528798,-0.5078096934092219,0.09374950248621658,3.4381474194828905,0.2450260771368476,-0.0634896107921604,0.09374950248621658,1.4323066040977575,2.4195100841990267,1.1505511630774563,-0.0038005361770060086,-0.6905032048336213,0.42631322556594947,-0.12407556372432456,-0.023598660010764588,-0.0835841298387108,0.42631322556594947,0.3548007225100377,0.055014368762545285,-0.22710959688583782,0.2450260771368476,0.15115574181980668,0.3907205059965324,-1.0306021517672246,-0.14447423395217424,-0.18558195150973228,0.1321121623528798,-0.6210539026805592,-0.22710959688583782,0.6833317551050844,0.42631322556594947,0.9859014847349855,0.015900464346774338,0.18897117543040606,-0.33281539857511017,-0.354287776657499,-1.0559648852353496,0.07442888489169129,-0.10377915671823269,0.3185486441921405,2.357634147809756,0.5825675708995396,-0.023598660010764588,1.486136587048457,0.18897117543040606
| 3,376
|
Apical part of cell
| 19
| 58
| 2.945626
| 0.003223
|
O43865,P04083,P05067,P55011,P08195,Q8IZT6,Q86UE4,Q9NV70,P11166,P41208,Q15154,P30825,Q99538,P53985,P61421,P08183,O75955,O00165,Q9Y4G8
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
386,393,143,411,525,27,286,553,408,168,560,56,184,199,456,216,343,602,373
|
602,1663,1737,1699,1664,1062,3080,386,770,343,393,628,1671,143,216,525,985,1442,408,1748,1878,3031,829,1123,2891,1630,56,1976,1977,1411,1223,1798,168,2722,199,1337,411,2235,456,2770,1038,1303,1039,2974,1681,1525,560,286,27,2163,184,2115,2070,553,1658,373,2550,861
|
0.6500364914113959,-0.10377915671823269,-0.14447423395217424,-0.12407556372432456,-0.10377915671823269,0.2264292404709339,-1.0053883317133208,1.0163834713233377,0.4615839958458578,1.1211517662256676,1.0011735038559333,0.6164499083295459,-0.10377915671823269,2.018667073067943,1.5391760995751391,0.7490655969974919,0.28195892039051096,0.015900464346774338,0.9705669749994547,-0.14447423395217424,-0.20629282062173515,-0.9306254080954044,0.4085574264207841,0.18897117543040606,-0.784923636467135,-0.0835841298387108,2.7958932046881895,-0.2480332200865538,-0.2480332200865538,0.03550516234149863,0.1321121623528798,-0.16497606147263494,1.829768258961035,-0.6440760551569396,1.6429624336734927,0.07442888489169129,0.9705669749994547,-0.37587289727828466,0.8772224665898438,-0.6672254158451334,0.2450260771368476,0.09374950248621658,0.2450260771368476,-0.8571497916635558,-0.10377915671823269,-0.023598660010764588,0.7163400404236764,1.3081910804853814,3.1659423425394335,-0.33281539857511017,1.7685881177452407,-0.31145474882693824,-0.2902048261296045,0.7327378977030797,-0.0835841298387108,1.0616453881949772,-0.5302135415922944,0.3907205059965324
| 3,376
|
Glycoside hydrolase superfamily [IPR017853]
| 8
| 16
| 2.945412
| 0.003225
|
P04066,P06865,O60502,P10253,P06280,P54802,P04062,P16278
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
291,262,47,182,310,121,90,93
|
47,90,291,310,262,1185,525,381,182,93,2055,121,708,2456,855,1650
|
2.9560208536056787,2.4902865084460193,1.2941363054249848,1.208658359818944,1.3776655599934584,0.15115574181980668,0.7490655969974919,1.0315318217278158,1.7685881177452407,2.470216891564265,-0.2902048261296045,2.1649209674192837,0.5311795854762361,-0.4855260677859258,0.3907205059965324,-0.0835841298387108
| 3,376
|
Retrograde transport endosome to golgi
| 12
| 38
| 2.942012
| 0.003261
|
O15260,O75503,O60499,Q9Y5X3,Q8NBN3,O43752,O95249,Q9BVK6,Q15836,Q9UBQ0,P40616,Q13190
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
39,137,41,566,12,200,201,332,436,89,544,474
|
39,1740,200,1621,1547,41,555,2132,137,201,2449,544,679,2318,2056,1225,2100,474,1343,1040,436,732,1896,1493,1387,2873,12,1354,1392,1853,332,1909,2041,89,880,3309,1324,566
|
3.016205187599177,-0.14447423395217424,1.630152502007486,-0.0835841298387108,-0.043494737915892735,3.007676347681497,0.7163400404236764,-0.33281539857511017,2.0415749265642926,1.630152502007486,-0.4855260677859258,0.7327378977030797,0.565514082039327,-0.41938548886236693,-0.2902048261296045,0.1321121623528798,-0.31145474882693824,0.8455870712937495,0.07442888489169129,0.2450260771368476,0.9241840457318883,0.5138974074088837,-0.20629282062173515,-0.0038005361770060086,0.055014368762545285,-0.7611195948253038,3.4381474194828905,0.07442888489169129,0.055014368762545285,-0.18558195150973228,1.1505511630774563,-0.20629282062173515,-0.26906464190792506,2.5002762814837243,0.372801821409757,-1.7433267771566325,0.09374950248621658,0.7163400404236764
| 3,376
|
Passive transmembrane transporter activity
| 9
| 34
| 2.939021
| 0.003293
|
Q9Y277,P00846,P21796,P45880,Q9NVV0,P24539,P51798,Q9C0H2,O75964
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
231,7,8,11,237,240,311,63,31
|
881,2134,31,557,7,1220,2786,1405,1187,8,240,2228,2143,1798,11,3086,311,1096,968,2568,1381,743,820,1044,1647,1500,2115,3257,63,237,362,2826,231,2550
|
0.3548007225100377,-0.33281539857511017,3.091955963388661,0.7163400404236764,3.576464581247993,0.1321121623528798,-0.6905032048336213,0.03550516234149863,0.15115574181980668,3.555036482266552,1.445839319599628,-0.37587289727828466,-0.33281539857511017,-0.16497606147263494,3.4381474194828905,-1.0053883317133208,1.208658359818944,0.2077445134366247,0.3002963271667747,-0.552738738110152,0.055014368762545285,0.4965378185069035,0.42631322556594947,0.2450260771368476,-0.0835841298387108,-0.0038005361770060086,-0.31145474882693824,-1.3999582054993458,2.7314251993438563,1.4593216736559882,1.0915175946894244,-0.7139106589140215,1.486136587048457,-0.5302135415922944
| 3,376
|
Cellular monovalent inorganic cation homeostasis
| 9
| 25
| 2.936936
| 0.003315
|
Q15904,Q9Y487,O75503,Q8N511,P61421,Q9HC07,P55011,P50897,Q93050
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
295,423,137,40,456,112,411,22,188
|
137,770,628,1671,1220,1187,1222,1974,22,2318,1337,411,456,1758,295,40,500,188,1906,112,1212,911,423,2550,861
|
2.0415749265642926,0.4615839958458578,0.6164499083295459,-0.10377915671823269,0.1321121623528798,0.15115574181980668,0.1321121623528798,-0.2480332200865538,3.2302833584863713,-0.41938548886236693,0.07442888489169129,0.9705669749994547,0.8772224665898438,-0.14447423395217424,1.251645809202598,3.016205187599177,0.7976328933322394,1.7313649796578738,-0.20629282062173515,2.294602822374333,0.15115574181980668,0.3548007225100377,0.9551695312607196,-0.5302135415922944,0.3907205059965324
| 3,376
|
Glycoprotein biosynthetic process
| 17
| 54
| 2.936254
| 0.003322
|
Q9Y5P6,Q99805,Q8WVQ1,Q9BXS4,Q9NQX7,Q8NCH0,O60502,Q92542,Q9HC07,Q2TAA5,Q86YN1,Q9H4A6,Q9BT22,O14734,Q10472,O15118,Q7LGA3
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
227,196,452,397,105,44,47,400,112,463,149,213,249,439,285,157,95
|
1436,439,157,2258,538,47,1741,3064,1668,2303,605,791,2483,2921,1976,1068,1192,461,3200,1197,2768,1342,1841,1199,285,2692,2374,463,801,95,2287,1592,149,44,2702,452,400,1565,979,1498,1001,196,249,397,3301,717,213,112,105,1857,3281,1212,227,1865
|
0.015900464346774338,0.9085950944992713,1.9136707952245202,-0.3975717877794668,0.7327378977030797,2.9560208536056787,-0.14447423395217424,-0.980321919952045,-0.10377915671823269,-0.41938548886236693,0.6500364914113959,0.4439885391534624,-0.5078096934092219,-0.808862463451572,-0.2480332200865538,0.2264292404709339,0.15115574181980668,0.8614378522891492,-1.2378047400733483,0.15115574181980668,-0.6672254158451334,0.07442888489169129,-0.18558195150973228,0.15115574181980668,1.3081910804853814,-0.6210539026805592,-0.44131505481374056,0.8614378522891492,0.4439885391534624,2.4398849348313916,-0.3975717877794668,-0.0634896107921604,1.9840190981550436,2.973331959590957,-0.6210539026805592,0.8929413902574874,0.9859014847349855,-0.043494737915892735,0.3002963271667747,-0.0038005361770060086,0.28195892039051096,1.6684451556620152,1.418723201036815,1.0011735038559333,-1.7136796782151344,0.5311795854762361,1.552314809182681,2.294602822374333,2.3783860185520687,-0.18558195150973228,-1.5398144784516654,0.15115574181980668,1.4994697838784592,-0.18558195150973228
| 3,376
|
Protein insertion into membrane
| 17
| 30
| 2.930136
| 0.003388
|
O43681,P49069,Q9NS69,Q9P0I2,Q5J8M3,Q7L5D6,O14737,Q53H12,O43765,P46379,Q15070,Q9Y5J9,Q8N4V1,Q15629,Q9P0J0,Q9Y512,Q96A33
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
506,569,2,684,519,521,298,744,703,140,243,737,19,50,283,416,346
|
298,2884,506,703,2305,1092,2310,2187,140,569,2568,2694,243,50,744,519,521,19,1849,762,346,908,2,684,283,1613,416,1146,737,1147
|
1.2373723709299225,-0.784923636467135,0.7815125855528189,0.5311795854762361,-0.41938548886236693,0.2077445134366247,-0.41938548886236693,-0.354287776657499,2.030139933980146,0.6998715023470454,-0.552738738110152,-0.6210539026805592,1.445839319599628,2.8946877773816957,0.4965378185069035,0.7653236556388097,0.7653236556388097,3.261966421590314,-0.18558195150973228,0.47910021734806124,1.1211517662256676,0.3548007225100377,4.3051831514783245,0.565514082039327,1.322192093055503,-0.0634896107921604,0.9705669749994547,0.18897117543040606,0.5138974074088837,0.18897117543040606
| 3,376
|
Optic disc pallor
| 13
| 55
| 2.929405
| 0.003396
|
P51798,P00846,Q9GZY8,Q9H061,Q6P4Q7,Q86Y39,O60313,Q96CU9,O96000,P04439,Q9H6K4,P03886,O43676
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
311,7,327,10,300,187,329,78,272,273,147,24,26
|
826,790,884,1510,26,2398,539,329,2049,367,2219,1670,2752,723,1372,272,7,24,273,2264,2448,2889,2089,2947,3226,311,2019,2897,2274,608,1039,300,187,2201,2160,1850,2112,1104,932,2624,78,1001,1500,2938,1360,327,10,958,147,613,1249,3012,1366,1659,721
|
0.4085574264207841,0.4439885391534624,0.3548007225100377,-0.023598660010764588,3.1659423425394335,-0.4633615537366067,0.7327378977030797,1.1505511630774563,-0.2902048261296045,1.0616453881949772,-0.37587289727828466,-0.10377915671823269,-0.6672254158451334,0.5138974074088837,0.055014368762545285,1.3361396976874031,3.576464581247993,3.214321038100156,1.3361396976874031,-0.3975717877794668,-0.4855260677859258,-0.784923636467135,-0.31145474882693824,-0.8329374006846979,-1.3181298258671186,1.208658359818944,-0.26906464190792506,-0.784923636467135,-0.3975717877794668,0.6500364914113959,0.2450260771368476,1.2373723709299225,1.7438162203898662,-0.354287776657499,-0.33281539857511017,-0.18558195150973228,-0.31145474882693824,0.2077445134366247,0.3367165517731276,-0.5753864237832664,2.5888606637088407,0.28195892039051096,-0.0038005361770060086,-0.808862463451572,0.07442888489169129,1.1651638225306005,3.460405813603222,0.3185486441921405,2.0071561264974758,0.6500364914113959,0.1321121623528798,-0.8815009988157699,0.07442888489169129,-0.0835841298387108,0.5311795854762361
| 3,376
|
Abnormal vascular physiology
| 13
| 50
| 2.929061
| 0.0034
|
P51798,Q8IZA0,Q14108,O75844,P04062,P00403,P05067,O96000,Q9Y4P3,P06280,P03886,P35250,Q9NZ08
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
311,164,37,88,90,267,143,272,276,310,24,315,127
|
2257,1326,807,1741,2220,1184,88,1515,272,267,2306,24,90,1473,143,310,3135,3116,793,1151,3097,2138,2228,3033,2269,1976,315,1884,1299,311,1015,2492,3054,2768,2494,37,2532,428,973,1561,780,164,1906,2006,351,127,2988,2300,276,2392
|
-0.3975717877794668,0.07442888489169129,0.42631322556594947,-0.14447423395217424,-0.37587289727828466,0.15115574181980668,2.5201665300557425,-0.023598660010764588,1.3361396976874031,1.3500342456184196,-0.41938548886236693,3.214321038100156,2.4902865084460193,-0.0038005361770060086,2.018667073067943,1.208658359818944,-1.1071432230243936,-1.0559648852353496,0.4439885391534624,0.17010849742073567,-1.0306021517672246,-0.33281539857511017,-0.37587289727828466,-0.9306254080954044,-0.3975717877794668,-0.2480332200865538,1.1942170327352566,-0.20629282062173515,0.09374950248621658,1.208658359818944,0.2635357357357556,-0.5078096934092219,-0.9554014328962437,-0.6672254158451334,-0.5078096934092219,3.050094664845848,-0.5302135415922944,0.9397087056445106,0.3002963271667747,-0.043494737915892735,0.4615839958458578,1.8539458215110518,-0.20629282062173515,-0.2480332200865538,1.1211517662256676,2.1094015983677914,-0.8571497916635558,-0.3975717877794668,1.3361396976874031,-0.44131505481374056
| 3,376
|
Transporter
| 78
| 196
| 2.927697
| 0.003415
|
O95563,Q15363,P00846,Q8N1F7,Q9BQT8,P35670,P08195,Q9BSK2,Q9P2W9,Q9NV70,O60499,Q9H2D1,O96008,O60749,P30825,Q9Y3B3,Q9UNK0,Q9UBX3,Q6PML9,Q9UBQ0,Q9Y3A6,Q8TEX9,Q8TB61,Q9HC07,Q70HW3,O43760,Q9UJS0,Q9HD45,P05023,Q9P253,P52292,Q9H2V7,Q99523,Q96K37,Q9Y619,P12235,O14579,P49257,Q86VD7,Q93050,Q99805,P53985,O43752,O95249,Q15388,Q8IXU6,Q9NZD2,Q6KCM7,P08183,Q15070,P24539,O95202,Q7L0J3,O75027,P16615,Q9BVK6,Q9C0E2,Q03518,Q12768,P17900,P11279,P50542,O60645,P55011,P11166,Q9Y487,O43772,Q9HC21,Q8WWI5,Q9NZJ7,O00560,P61421,Q9H6H4,Q13190,Q9Y6C9,P49755,Q92544,P12236
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
508,5,7,532,533,526,525,28,29,553,41,42,557,555,56,57,575,83,594,89,615,623,109,112,113,114,642,122,628,656,648,142,668,667,675,154,657,679,177,188,196,199,200,201,206,207,210,212,216,243,240,238,281,289,302,332,341,334,335,353,356,382,387,411,408,423,432,438,443,444,446,456,478,474,490,485,500,497
|
2636,1663,2046,2129,1399,446,657,2961,1326,3169,1329,1062,200,114,432,2009,41,387,863,2811,555,1669,289,2132,769,2134,1514,238,201,2050,2221,2482,508,1874,557,7,628,1671,1118,1220,216,525,1876,2966,408,356,154,497,302,353,829,1123,2891,240,2228,2015,2185,56,1191,526,2143,1933,1798,2722,1836,2368,679,485,382,1154,988,648,1259,773,2813,2320,2997,199,2057,1337,1070,411,1096,968,1227,456,2568,2925,3227,2237,1262,1300,2100,798,1158,334,1841,949,335,1037,1159,831,474,1039,3041,1343,2281,1894,243,3022,2900,5,206,1384,898,1684,212,3356,780,695,2196,594,113,281,1813,177,871,207,532,1390,1169,109,2423,623,1313,443,500,802,188,1906,1132,667,1532,1853,1207,668,1135,196,533,2467,28,332,341,3301,805,42,3166,142,478,1138,1604,112,438,122,1732,982,1543,553,210,444,1656,2435,656,29,2076,89,83,911,2296,642,575,3286,1251,1658,939,1085,615,57,423,2081,840,825,675,1026,490,861
|
-0.5981577547393172,-0.10377915671823269,-0.2902048261296045,-0.33281539857511017,0.03550516234149863,0.8929413902574874,0.5825675708995396,-0.8571497916635558,0.07442888489169129,-1.185066492546918,0.07442888489169129,0.2264292404709339,1.630152502007486,2.2411669014570372,0.9241840457318883,-0.26906464190792506,3.007676347681497,1.0163834713233377,0.372801821409757,-0.7139106589140215,0.7163400404236764,-0.10377915671823269,1.2941363054249848,-0.33281539857511017,0.4615839958458578,-0.33281539857511017,-0.023598660010764588,1.445839319599628,1.630152502007486,-0.2902048261296045,-0.37587289727828466,-0.5078096934092219,0.7815125855528189,-0.20629282062173515,0.7163400404236764,3.576464581247993,0.6164499083295459,-0.10377915671823269,0.18897117543040606,0.1321121623528798,1.5391760995751391,0.7490655969974919,-0.20629282062173515,-0.8571497916635558,0.9705669749994547,1.0915175946894244,1.9607270744213334,0.7976328933322394,1.2230433462408152,1.1063642295621396,0.4085574264207841,0.18897117543040606,-0.784923636467135,1.445839319599628,-0.37587289727828466,-0.26906464190792506,-0.354287776657499,2.7958932046881895,0.15115574181980668,0.7490655969974919,-0.33281539857511017,-0.22710959688583782,-0.16497606147263494,-0.6440760551569396,-0.18558195150973228,-0.44131505481374056,0.565514082039327,0.8296696426224738,1.0315318217278158,0.17010849742073567,0.28195892039051096,0.5995459898347874,0.11297700392516687,0.4615839958458578,-0.7139106589140215,-0.41938548886236693,-0.8815009988157699,1.6429624336734927,-0.2902048261296045,0.07442888489169129,0.2264292404709339,0.9705669749994547,0.2077445134366247,0.3002963271667747,0.1321121623528798,0.8772224665898438,-0.552738738110152,-0.808862463451572,-1.3181298258671186,-0.37587289727828466,0.11297700392516687,0.09374950248621658,-0.31145474882693824,0.4439885391534624,0.17010849742073567,1.135880610204166,-0.18558195150973228,0.3185486441921405,1.135880610204166,0.2450260771368476,0.17010849742073567,0.4085574264207841,0.8455870712937495,0.2450260771368476,-0.9306254080954044,0.07442888489169129,-0.3975717877794668,-0.20629282062173515,1.445839319599628,-0.9059924038468624,-0.784923636467135,3.708771690562757,1.5784489587449075,0.055014368762545285,0.3548007225100377,-0.10377915671823269,1.552314809182681,-2.699266327650186,0.4615839958458578,0.5483849475613088,-0.354287776657499,0.6667202646970376,2.262642140545865,1.322192093055503,-0.16497606147263494,1.7931876481313542,0.372801821409757,1.5784489587449075,0.7490655969974919,0.055014368762545285,0.17010849742073567,2.3262652314834207,-0.4633615537366067,0.6332798897464621,0.09374950248621658,0.9085950944992713,0.7976328933322394,0.4439885391534624,1.7313649796578738,-0.20629282062173515,0.18897117543040606,0.5825675708995396,-0.023598660010764588,-0.18558195150973228,0.15115574181980668,0.5825675708995396,0.18897117543040606,1.6684451556620152,0.7490655969974919,-0.4855260677859258,3.1496497632836333,1.1505511630774563,1.135880610204166,-1.7136796782151344,0.4439885391534624,2.990550171469064,-1.1589358324480967,2.030139933980146,0.8455870712937495,0.18897117543040606,-0.0634896107921604,2.294602822374333,0.9241840457318883,2.1649209674192837,-0.12407556372432456,0.3002963271667747,-0.023598660010764588,0.7327378977030797,1.56540566205142,0.9085950944992713,-0.0835841298387108,-0.4633615537366067,0.5995459898347874,3.1414718652717917,-0.2902048261296045,2.5002762814837243,2.5595940969002076,0.3548007225100377,-0.3975717877794668,0.6164499083295459,0.6998715023470454,-1.5683244293101335,0.1321121623528798,-0.0835841298387108,0.3367165517731276,0.2264292404709339,0.6500364914113959,2.786761095827931,0.9551695312607196,-0.2902048261296045,0.4085574264207841,0.42631322556594947,0.5825675708995396,0.2635357357357556,0.8296696426224738,0.3907205059965324
| 3,376
|
Electron transport
| 12
| 49
| 2.923233
| 0.003464
|
Q9UDW1,P00403,Q86Y39,Q96CU9,O96000,O43169,Q9P0J0,Q9H1E5,P03886,O14949,O43676,Q6DKK2
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
74,267,187,78,272,18,283,86,24,87,26,253
|
1618,87,18,941,2716,26,1028,2049,367,1670,278,704,2443,2603,272,267,24,1186,3126,3145,2889,918,2893,754,2947,2450,889,2452,3019,2316,3226,1015,2019,925,2412,1895,1235,253,187,78,2250,86,906,1249,283,74,3258,1178,721
|
-0.0835841298387108,2.530067311521496,3.2933320299293305,0.3185486441921405,-0.6440760551569396,3.1659423425394335,0.2450260771368476,-0.2902048261296045,1.0616453881949772,-0.10377915671823269,1.322192093055503,0.5311795854762361,-0.4855260677859258,-0.5753864237832664,1.3361396976874031,1.3500342456184196,3.214321038100156,0.15115574181980668,-1.0814780591807345,-1.132961948971579,-0.784923636467135,0.3367165517731276,-0.784923636467135,0.47910021734806124,-0.8329374006846979,-0.4855260677859258,0.3548007225100377,-0.4855260677859258,-0.9059924038468624,-0.41938548886236693,-1.3181298258671186,0.2635357357357556,-0.26906464190792506,0.3367165517731276,-0.4633615537366067,-0.20629282062173515,0.1321121623528798,1.4050887812930244,1.7438162203898662,2.5888606637088407,-0.37587289727828466,2.5399387332030887,0.3548007225100377,0.1321121623528798,1.322192093055503,2.617870951389883,-1.3999582054993458,0.17010849742073567,0.5311795854762361
| 3,376
|
Tclin
| 23
| 89
| 2.9204
| 0.003496
|
P04035,O96000,P38435,Q7L0J3,Q9P0J0,P55011,P03886,O95168,O43676,P21964,P00813,P10253,P06280,Q86Y39,Q16739,Q13464,P49841,Q99720,P49721,P49840,P00374,P20618,O75306
|
Drugs and Diseases
|
Pharos IDG Category
|
pharos_protein_category
|
261,272,148,281,283,411,24,278,26,409,49,182,310,187,64,322,330,96,99,364,110,239,367
|
1618,2716,26,1028,1400,2049,367,1670,278,704,2443,272,110,1519,2719,49,24,261,1012,628,1671,1580,1796,310,792,2833,2052,448,182,2446,1746,3186,3115,944,2225,965,2402,2889,239,2089,409,1927,1831,543,2857,687,2947,1673,688,1754,148,1224,3341,99,3226,364,330,1837,1015,1337,411,2019,892,1157,1341,1937,971,1413,322,868,1232,662,2412,64,1895,1235,281,187,2160,1456,96,2938,1359,1693,1249,3012,283,3258,721
|
-0.0835841298387108,-0.6440760551569396,3.1659423425394335,0.2450260771368476,0.03550516234149863,-0.2902048261296045,1.0616453881949772,-0.10377915671823269,1.322192093055503,0.5311795854762361,-0.4855260677859258,1.3361396976874031,2.315743939212719,-0.023598660010764588,-0.6440760551569396,2.9211164682126753,3.214321038100156,1.3776655599934584,0.2635357357357556,0.6164499083295459,-0.10377915671823269,-0.0634896107921604,-0.16497606147263494,1.208658359818944,0.4439885391534624,-0.7374490318787568,-0.2902048261296045,0.8929413902574874,1.7685881177452407,-0.4855260677859258,-0.14447423395217424,-1.2113555724853857,-1.0559648852353496,0.3185486441921405,-0.37587289727828466,0.3002963271667747,-0.4633615537366067,-0.784923636467135,1.445839319599628,-0.31145474882693824,0.9705669749994547,-0.22710959688583782,-0.18558195150973228,0.7327378977030797,-0.7611195948253038,0.5483849475613088,-0.8329374006846979,-0.10377915671823269,0.5483849475613088,-0.14447423395217424,1.9956068751611455,0.1321121623528798,-2.3468748883404933,2.4195100841990267,-1.3181298258671186,1.0766114520886294,1.1505511630774563,-0.18558195150973228,0.2635357357357556,0.07442888489169129,0.9705669749994547,-0.26906464190792506,0.3548007225100377,0.17010849742073567,0.07442888489169129,-0.22710959688583782,0.3002963271667747,0.03550516234149863,1.179718982402758,0.372801821409757,0.1321121623528798,0.5825675708995396,-0.4633615537366067,2.7127698952516086,-0.20629282062173515,0.1321121623528798,1.322192093055503,1.7438162203898662,-0.33281539857511017,0.015900464346774338,2.4398849348313916,-0.808862463451572,0.07442888489169129,-0.10377915671823269,0.1321121623528798,-0.8815009988157699,1.322192093055503,-1.3999582054993458,0.5311795854762361
| 3,376
|
Ion channel transport
| 11
| 29
| 2.912481
| 0.003586
|
P27105,Q9NW15,Q9Y487,Q15904,Q9HD20,P61421,Q13555,P16615,P51798,Q93050,Q9C0H2
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
163,362,423,295,135,456,528,302,311,188,63
|
628,1671,302,829,1123,2891,163,1445,526,1411,1798,311,1337,456,1262,1938,1161,528,295,743,188,935,63,1694,135,362,911,423,2081
|
0.6164499083295459,-0.10377915671823269,1.2230433462408152,0.4085574264207841,0.18897117543040606,-0.784923636467135,1.8539458215110518,0.015900464346774338,0.7490655969974919,0.03550516234149863,-0.16497606147263494,1.208658359818944,0.07442888489169129,0.8772224665898438,0.11297700392516687,-0.22710959688583782,0.17010849742073567,0.7490655969974919,1.251645809202598,0.4965378185069035,1.7313649796578738,0.3367165517731276,2.7314251993438563,-0.10377915671823269,2.0529722663918206,1.0915175946894244,0.3548007225100377,0.9551695312607196,-0.2902048261296045
| 3,376
|
Ion transmembrane transport
| 55
| 167
| 2.911938
| 0.003592
|
O43865,O95563,Q8N668,P00846,P21796,Q9HD20,P45880,P07384,P00403,P05067,Q96GC9,Q9UHG3,Q9BQT8,Q8N4V1,P55011,P35670,P12235,O75964,P13073,O75027,P27105,Q9H2D1,Q6P4Q7,O43772,Q86VD7,P16615,Q9HC21,P30825,P51798,Q9C0H2,P0DP25,P46934,Q13423,P53985,O75915,Q9UDW1,P61421,Q9UBX3,Q6KCM7,O75844,P08183,P78417,Q9NRA0,Q9Y277,Q6P4A7,Q9NW15,O60831,Q8TB61,Q9NVV0,Q9HC07,Q70HW3,P24539,O95202,Q9HD26,P12236
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
386,508,390,7,8,135,11,394,267,143,144,17,533,19,411,526,154,31,161,289,163,42,300,432,177,302,438,56,311,63,448,193,194,199,454,74,456,83,212,88,216,94,489,231,230,362,483,109,237,112,113,240,238,501,497
|
881,2083,1618,1437,1699,1062,1216,432,2009,386,1968,483,289,2218,2049,2219,769,88,454,2134,31,238,508,2444,267,7,628,1671,143,1118,1796,1220,2786,394,1405,216,525,1186,1187,448,2012,1292,154,497,161,302,2447,1829,3117,829,793,1123,2891,3097,8,240,2228,163,2092,1930,2994,1445,56,889,526,2452,2143,1411,1798,2722,1412,11,193,2146,2316,3086,730,311,773,199,1710,1337,411,1096,968,456,2568,776,94,1262,1300,1381,1158,778,3071,3253,1038,194,1161,1162,1201,1265,570,2900,1344,1384,2933,743,212,230,300,594,2198,113,1386,177,2582,834,19,390,820,109,1044,762,1647,144,2250,1532,2803,1208,3297,654,533,1459,3257,63,3301,3374,42,3166,1694,1138,1604,112,438,135,501,489,1543,237,362,83,74,1212,17,911,642,1431,2826,231,1658,2254,1864,1659,675,2550,861
|
0.3548007225100377,-0.31145474882693824,-0.0835841298387108,0.015900464346774338,-0.12407556372432456,0.2264292404709339,0.1321121623528798,0.9241840457318883,-0.26906464190792506,1.0163834713233377,-0.2480332200865538,0.8296696426224738,1.2941363054249848,-0.37587289727828466,-0.2902048261296045,-0.37587289727828466,0.4615839958458578,2.5201665300557425,0.8772224665898438,-0.33281539857511017,3.091955963388661,1.445839319599628,0.7815125855528189,-0.4855260677859258,1.3500342456184196,3.576464581247993,0.6164499083295459,-0.10377915671823269,2.018667073067943,0.18897117543040606,-0.16497606147263494,0.1321121623528798,-0.6905032048336213,1.0011735038559333,0.03550516234149863,1.5391760995751391,0.7490655969974919,0.15115574181980668,0.15115574181980668,0.8929413902574874,-0.26906464190792506,0.09374950248621658,1.9607270744213334,0.7976328933322394,1.8659724939578621,1.2230433462408152,-0.4855260677859258,-0.18558195150973228,-1.0559648852353496,0.4085574264207841,0.4439885391534624,0.18897117543040606,-0.784923636467135,-1.0306021517672246,3.555036482266552,1.445839319599628,-0.37587289727828466,1.8539458215110518,-0.31145474882693824,-0.22710959688583782,-0.8815009988157699,0.015900464346774338,2.7958932046881895,0.3548007225100377,0.7490655969974919,-0.4855260677859258,-0.33281539857511017,0.03550516234149863,-0.16497606147263494,-0.6440760551569396,0.03550516234149863,3.4381474194828905,1.6811185084368743,-0.33281539857511017,-0.41938548886236693,-1.0053883317133208,0.5138974074088837,1.208658359818944,0.4615839958458578,1.6429624336734927,-0.12407556372432456,0.07442888489169129,0.9705669749994547,0.2077445134366247,0.3002963271667747,0.8772224665898438,-0.552738738110152,0.4615839958458578,2.470216891564265,0.11297700392516687,0.09374950248621658,0.055014368762545285,0.17010849742073567,0.4615839958458578,-0.980321919952045,-1.3999582054993458,0.2450260771368476,1.6684451556620152,0.17010849742073567,0.17010849742073567,0.15115574181980668,0.11297700392516687,0.6998715023470454,-0.784923636467135,0.07442888489169129,0.055014368762545285,-0.808862463451572,0.4965378185069035,1.552314809182681,1.486136587048457,1.2373723709299225,0.6667202646970376,-0.354287776657499,2.262642140545865,0.055014368762545285,1.7931876481313542,-0.552738738110152,0.4085574264207841,3.261966421590314,1.0163834713233377,0.42631322556594947,2.3262652314834207,0.2450260771368476,0.47910021734806124,-0.0835841298387108,2.018667073067943,-0.37587289727828466,-0.023598660010764588,-0.6905032048336213,0.15115574181980668,-1.6549680395922322,0.5995459898347874,0.7490655969974919,0.015900464346774338,-1.3999582054993458,2.7314251993438563,-1.7136796782151344,-7.480312896931482,2.990550171469064,-1.1589358324480967,-0.10377915671823269,0.18897117543040606,-0.0634896107921604,2.294602822374333,0.9241840457318883,2.0529722663918206,0.7976328933322394,0.8296696426224738,-0.023598660010764588,1.4593216736559882,1.0915175946894244,2.5595940969002076,2.617870951389883,0.15115574181980668,3.3551325867531854,0.3548007225100377,0.6164499083295459,0.03550516234149863,-0.7139106589140215,1.486136587048457,-0.0835841298387108,-0.37587289727828466,-0.18558195150973228,-0.0835841298387108,0.5825675708995396,-0.5302135415922944,0.3907205059965324
| 3,376
|
Carboxylic acid transport
| 19
| 37
| 2.906054
| 0.00366
|
O95563,P04083,O75746,Q9BQT8,Q7L0J3,P55011,P08195,Q9Y619,Q9H2D1,P14174,P30825,Q9NZJ7,Q15041,P53985,O75915,Q9UBX3,P07602,O60831,Q9UJS0
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
508,393,769,533,281,411,525,675,42,677,56,444,570,199,454,83,333,483,642
|
1699,3133,1062,483,769,454,508,393,1796,333,525,677,2015,56,2722,773,199,411,1158,1303,570,2283,1384,2196,281,1044,1532,533,42,3166,1138,1604,444,83,642,1658,675
|
-0.12407556372432456,-1.1071432230243936,0.2264292404709339,0.8296696426224738,0.4615839958458578,0.8772224665898438,0.7815125855528189,1.0011735038559333,-0.16497606147263494,1.135880610204166,0.7490655969974919,0.565514082039327,-0.26906464190792506,2.7958932046881895,-0.6440760551569396,0.4615839958458578,1.6429624336734927,0.9705669749994547,0.17010849742073567,0.09374950248621658,0.6998715023470454,-0.3975717877794668,0.055014368762545285,-0.354287776657499,1.322192093055503,0.2450260771368476,-0.023598660010764588,0.7490655969974919,2.990550171469064,-1.1589358324480967,0.18897117543040606,-0.0634896107921604,0.9085950944992713,2.5595940969002076,0.6164499083295459,-0.0835841298387108,0.5825675708995396
| 3,376
|
Hyperlipidemia
| 10
| 30
| 2.901036
| 0.003719
|
P22830,P50416,O95470,P28070,P31751,O75431,Q13045,P06280,O75844,P23786
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
128,359,265,138,232,392,399,310,88,120
|
2047,1216,392,88,265,2306,310,1440,128,120,138,1673,232,2055,2922,679,417,359,2321,399,1641,1162,898,2580,2290,1496,1355,1171,642,912
|
-0.2902048261296045,0.1321121623528798,1.0011735038559333,2.5201665300557425,1.3638760848112592,-0.41938548886236693,1.208658359818944,0.015900464346774338,2.098189349032581,2.1649209674192837,2.0415749265642926,-0.10377915671823269,1.4727539894057913,-0.2902048261296045,-0.808862463451572,0.565514082039327,0.9551695312607196,1.0915175946894244,-0.41938548886236693,0.9859014847349855,-0.0835841298387108,0.17010849742073567,0.3548007225100377,-0.552738738110152,-0.3975717877794668,-0.0038005361770060086,0.07442888489169129,0.17010849742073567,0.6164499083295459,0.3548007225100377
| 3,376
|
Action tremor
| 19
| 59
| 2.900612
| 0.003724
|
O43681,P00846,Q96RL7,Q9H6K4,P03886,Q9NR77,Q5JRX3,O14773,Q9BYI3,O75027,Q14108,Q6PJG6,Q9NZJ7,Q9UBB4,P35637,P07602,Q99720,Q9NW15,O75306
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
506,7,146,147,24,153,412,25,552,289,37,429,444,600,460,333,96,362,367
|
3204,25,2047,1664,506,289,367,1149,770,723,2050,7,24,1623,333,2011,2486,1925,1830,1926,1254,2091,2995,460,2722,1886,2097,1069,1709,2407,1987,3071,37,1559,1452,412,899,1167,2731,429,1526,1687,3289,624,146,2803,2429,96,1004,552,147,1606,153,362,444,600,1007,3096,1659
|
-1.2644156881924795,3.190224570239214,-0.2902048261296045,-0.10377915671823269,0.7815125855528189,1.2941363054249848,1.0616453881949772,0.17010849742073567,0.4615839958458578,0.5138974074088837,-0.2902048261296045,3.576464581247993,3.214321038100156,-0.0835841298387108,1.135880610204166,-0.26906464190792506,-0.5078096934092219,-0.22710959688583782,-0.18558195150973228,-0.22710959688583782,0.11297700392516687,-0.31145474882693824,-0.8815009988157699,0.8614378522891492,-0.6440760551569396,-0.20629282062173515,-0.31145474882693824,0.2264292404709339,-0.12407556372432456,-0.4633615537366067,-0.2480332200865538,-0.980321919952045,3.050094664845848,-0.043494737915892735,0.015900464346774338,0.9705669749994547,0.3548007225100377,0.17010849742073567,-0.6440760551569396,0.9397087056445106,-0.023598660010764588,-0.10377915671823269,-1.5970186221481857,0.6332798897464621,2.0071561264974758,-0.6905032048336213,-0.4633615537366067,2.4398849348313916,0.28195892039051096,0.7327378977030797,2.0071561264974758,-0.0634896107921604,1.9723925727598306,1.0915175946894244,0.9085950944992713,0.6667202646970376,0.28195892039051096,-1.0053883317133208,-0.0835841298387108
| 3,376
|
Cytoprotection by hmox1
| 18
| 68
| 2.90045
| 0.003726
|
P13073,P30519,O75880,Q96I36,P61289,P49721,P25787,P28070,P00403,P09601,Q9UL46,Q14997,P20618,P28072,Q9P0S2,P49720,Q8TCT9,Q92530
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
161,33,290,420,450,99,263,138,267,15,503,211,239,179,214,244,514,384
|
701,2440,2808,1618,1285,1437,2301,1330,886,1117,1090,290,267,15,2012,161,1189,1628,2834,239,793,543,263,2090,2720,1880,138,179,687,33,2721,3274,2837,1296,1032,244,99,1481,866,2788,810,450,1714,1523,1636,1196,813,1382,1759,2690,2278,2496,662,211,1941,1344,2108,514,384,420,2705,1134,2168,1459,214,503,1545,1215
|
0.5311795854762361,-0.4855260677859258,-0.7139106589140215,-0.0835841298387108,0.09374950248621658,0.015900464346774338,-0.41938548886236693,0.07442888489169129,0.3548007225100377,0.18897117543040606,0.2077445134366247,1.2941363054249848,1.3500342456184196,3.3779946752279097,-0.26906464190792506,1.8659724939578621,0.15115574181980668,-0.0835841298387108,-0.7374490318787568,1.445839319599628,0.4439885391534624,0.7327378977030797,1.3776655599934584,-0.31145474882693824,-0.6440760551569396,-0.20629282062173515,2.0415749265642926,1.7809092990421234,0.5483849475613088,3.083627658114699,-0.6440760551569396,-1.5114867338900893,-0.7374490318787568,0.09374950248621658,0.2450260771368476,1.4323066040977575,2.4195100841990267,-0.0038005361770060086,0.372801821409757,-0.6905032048336213,0.42631322556594947,0.8929413902574874,-0.12407556372432456,-0.023598660010764588,-0.0835841298387108,0.15115574181980668,0.42631322556594947,0.055014368762545285,-0.14447423395217424,-0.6210539026805592,-0.3975717877794668,-0.5078096934092219,0.5825675708995396,1.552314809182681,-0.22710959688583782,0.07442888489169129,-0.31145474882693824,0.7815125855528189,1.0315318217278158,0.9551695312607196,-0.6210539026805592,0.18897117543040606,-0.33281539857511017,0.015900464346774338,1.552314809182681,0.7976328933322394,-0.023598660010764588,0.15115574181980668
| 3,376
|
Glycosidase
| 8
| 18
| 2.893067
| 0.003815
|
P04066,P06865,O60502,P10253,P06280,P54802,P04062,P16278
|
Functions
|
Protein Atlas Molecular function
|
protein_atlas_molecular_function
|
291,262,47,182,310,121,90,93
|
790,1666,47,90,291,310,262,1185,381,182,93,2921,2055,121,2692,2456,855,1657
|
0.4439885391534624,-0.10377915671823269,2.9560208536056787,2.4902865084460193,1.2941363054249848,1.208658359818944,1.3776655599934584,0.15115574181980668,1.0315318217278158,1.7685881177452407,2.470216891564265,-0.808862463451572,-0.2902048261296045,2.1649209674192837,-0.6210539026805592,-0.4855260677859258,0.3907205059965324,-0.0835841298387108
| 3,376
|
Vacuole
| 66
| 217
| 2.889963
| 0.003853
|
Q8WTV0,P06865,P08236,Q9NX40,O75503,Q9BXS4,P07384,Q9H2V7,Q96GC9,Q9UHG3,Q96RL7,Q92542,P38435,Q15165,P50897,O14773,O15118,P27105,P04066,Q14108,Q8N511,O15260,Q9Y487,Q9UM22,Q9UIQ6,P00813,P10253,P06280,Q99538,P51798,Q14849,Q9NZJ7,Q93050,O00560,Q07065,Q9UMR5,P10619,Q969Q5,P11117,P15586,Q86YV9,Q9H7Z7,P61421,Q5BJF2,Q8IV08,Q9BRF8,Q8NCC3,P07602,Q8NF37,P04062,Q96A57,P16278,O75955,P17900,Q9Y6I9,P42785,Q9NRA0,Q9NQX7,P11279,Q8NHP8,Q13510,Q9HC07,P42892,P20645,P54802,O00584
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
130,262,381,264,137,397,394,142,144,17,146,400,148,21,22,25,157,163,291,37,40,39,423,43,309,49,182,310,184,311,58,444,188,446,321,66,68,69,197,319,326,459,456,77,81,209,85,333,464,90,347,93,343,353,228,101,489,105,356,108,111,112,118,374,121,252
|
2636,2046,446,252,790,2961,1326,25,1327,157,39,1329,1620,1511,506,1920,1621,555,646,1116,2400,2132,137,770,343,2915,1874,2754,2222,1404,49,90,291,2483,310,262,2786,394,792,333,1185,1092,1405,525,381,1442,1443,1876,1291,182,68,197,2136,1551,356,319,93,3268,353,374,2089,1123,2891,2606,163,2092,3033,1974,2519,1832,1031,1257,1411,148,2922,1798,1192,2722,1224,101,1412,118,1193,1980,1835,1522,1982,22,1634,689,2147,2318,2056,311,988,1802,2997,1887,121,2148,1016,2235,1711,1677,1838,456,812,3227,2237,1485,892,992,2100,1263,2151,2152,1805,321,3253,949,1159,3350,1716,1039,897,111,1343,37,2615,2693,58,21,898,77,1812,1590,326,81,952,40,2421,85,464,1389,108,2111,130,1851,400,785,188,69,347,1906,1018,3076,1132,144,1853,146,2168,668,551,184,2207,2666,1726,209,854,855,3375,1650,397,716,958,3301,805,1320,142,459,112,501,1109,105,489,1541,3111,264,2176,1049,444,1656,2435,656,1465,2041,767,17,911,309,700,43,3014,66,1396,575,1962,824,1179,720,685,1086,423,1144,2081,913,228
|
-0.5981577547393172,-0.2902048261296045,0.8929413902574874,1.4050887812930244,0.4439885391534624,-0.8571497916635558,0.07442888489169129,3.190224570239214,0.07442888489169129,1.9136707952245202,3.016205187599177,0.07442888489169129,-0.0835841298387108,-0.023598660010764588,0.7815125855528189,-0.22710959688583782,-0.0835841298387108,0.7163400404236764,0.5995459898347874,0.18897117543040606,-0.4633615537366067,-0.33281539857511017,2.0415749265642926,0.4615839958458578,1.1211517662256676,-0.808862463451572,-0.20629282062173515,-0.6672254158451334,-0.37587289727828466,0.03550516234149863,2.9211164682126753,2.4902865084460193,1.2941363054249848,-0.5078096934092219,1.208658359818944,1.3776655599934584,-0.6905032048336213,1.0011735038559333,0.4439885391534624,1.135880610204166,0.15115574181980668,0.2077445134366247,0.03550516234149863,0.7490655969974919,1.0315318217278158,0.015900464346774338,0.015900464346774338,-0.20629282062173515,0.09374950248621658,1.7685881177452407,2.67513802823974,1.655726557404686,-0.33281539857511017,-0.043494737915892735,1.0915175946894244,1.179718982402758,2.470216891564265,-1.4833391917688719,1.1063642295621396,1.046618985345816,-0.31145474882693824,0.18897117543040606,-0.784923636467135,-0.5753864237832664,1.8539458215110518,-0.31145474882693824,-0.9306254080954044,-0.2480332200865538,-0.5302135415922944,-0.18558195150973228,0.2450260771368476,0.11297700392516687,0.03550516234149863,1.9956068751611455,-0.808862463451572,-0.16497606147263494,0.15115574181980668,-0.6440760551569396,0.1321121623528798,2.4092761099767857,0.03550516234149863,2.186879575171654,0.15115574181980668,-0.2480332200865538,-0.18558195150973228,-0.023598660010764588,-0.2480332200865538,3.2302833584863713,-0.0835841298387108,0.5483849475613088,-0.33281539857511017,-0.41938548886236693,-0.2902048261296045,1.208658359818944,0.28195892039051096,-0.16497606147263494,-0.8815009988157699,-0.20629282062173515,2.1649209674192837,-0.33281539857511017,0.2635357357357556,-0.37587289727828466,-0.12407556372432456,-0.10377915671823269,-0.18558195150973228,0.8772224665898438,0.42631322556594947,-1.3181298258671186,-0.37587289727828466,-0.0038005361770060086,0.3548007225100377,0.28195892039051096,-0.31145474882693824,0.11297700392516687,-0.33281539857511017,-0.33281539857511017,-0.16497606147263494,1.179718982402758,-1.3999582054993458,0.3185486441921405,0.17010849742073567,-2.590750269625765,-0.12407556372432456,0.2450260771368476,0.3548007225100377,2.315743939212719,0.07442888489169129,3.050094664845848,-0.5753864237832664,-0.6210539026805592,2.7684197758655547,3.2382341893005746,0.3548007225100377,2.5888606637088407,-0.16497606147263494,-0.0634896107921604,1.1651638225306005,2.5693783360444082,0.3185486441921405,3.016205187599177,-0.4633615537366067,2.5497809452946028,0.8614378522891492,0.055014368762545285,2.3262652314834207,-0.31145474882693824,2.0869404990527856,-0.18558195150973228,0.9859014847349855,0.4615839958458578,1.7313649796578738,2.67513802823974,1.1211517662256676,-0.20629282062173515,0.2635357357357556,-0.980321919952045,0.18897117543040606,2.018667073067943,-0.18558195150973228,2.0071561264974758,-0.33281539857511017,0.5825675708995396,0.7327378977030797,1.7685881177452407,-0.354287776657499,-0.5981577547393172,-0.12407556372432456,1.56540566205142,0.3907205059965324,0.3907205059965324,-10.297987524474602,-0.0835841298387108,1.0011735038559333,0.5311795854762361,0.3185486441921405,-1.7136796782151344,0.4439885391534624,0.09374950248621658,2.030139933980146,0.8772224665898438,2.294602822374333,0.7976328933322394,0.2077445134366247,2.3783860185520687,0.8296696426224738,-0.023598660010764588,-1.0306021517672246,1.3776655599934584,-0.33281539857511017,0.2450260771368476,0.9085950944992713,-0.0835841298387108,-0.4633615537366067,0.5995459898347874,0.015900464346774338,-0.26906464190792506,0.47910021734806124,3.3551325867531854,0.3548007225100377,1.2230433462408152,0.5483849475613088,2.990550171469064,-0.8815009988157699,2.703402284279324,0.055014368762545285,0.6998715023470454,-0.22710959688583782,0.42631322556594947,0.17010849742073567,0.5311795854762361,0.565514082039327,0.2264292404709339,0.9551695312607196,0.18897117543040606,-0.2902048261296045,0.3548007225100377,1.4994697838784592
| 3,376
|
Biliary tract abnormality
| 13
| 29
| 2.874494
| 0.004047
|
O43681,Q10713,Q14108,O43933,Q14739,O96028,P09601,O95202,Q9UJW0,P07602,P50542,Q9NZJ7,P04062
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
506,608,37,539,428,172,15,238,502,333,382,444,90
|
506,539,238,172,2306,90,333,15,677,2404,2230,1376,382,1756,1069,608,1302,2373,37,428,849,2507,980,1210,1211,444,502,1613,840
|
0.7815125855528189,0.7327378977030797,1.445839319599628,1.8176168745831065,-0.41938548886236693,2.4902865084460193,1.135880610204166,3.3779946752279097,0.565514082039327,-0.4633615537366067,-0.37587289727828466,0.055014368762545285,1.0315318217278158,-0.14447423395217424,0.2264292404709339,0.6500364914113959,0.09374950248621658,-0.44131505481374056,3.050094664845848,0.9397087056445106,0.3907205059965324,-0.5078096934092219,0.3002963271667747,0.15115574181980668,0.15115574181980668,0.9085950944992713,0.7976328933322394,-0.0634896107921604,0.4085574264207841
| 3,376
|
Copii coated er to golgi transport vesicle
| 15
| 30
| 2.85986
| 0.004238
|
P10321,Q9Y282,Q15436,O15027,Q15363,P49755,Q9NR31,Q9BVK6,O95070,P05067,P04439,Q969X5,Q9Y3B3,Q9Y3A6,Q13190
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
509,97,486,627,5,485,625,332,204,143,273,339,57,615,474
|
627,1669,2303,2131,1514,204,2221,2482,273,143,509,679,485,2057,1841,831,474,5,486,3072,2460,339,1318,332,625,2779,97,615,57,1368
|
0.6164499083295459,-0.10377915671823269,-0.41938548886236693,-0.33281539857511017,-0.023598660010764588,1.6043940725091548,-0.37587289727828466,-0.5078096934092219,1.3361396976874031,2.018667073067943,0.7815125855528189,0.565514082039327,0.8296696426224738,-0.2902048261296045,-0.18558195150973228,0.4085574264207841,0.8455870712937495,3.708771690562757,0.8296696426224738,-0.980321919952045,-0.4855260677859258,1.135880610204166,0.09374950248621658,1.1505511630774563,0.6332798897464621,-0.6672254158451334,2.4398849348313916,0.6500364914113959,2.786761095827931,0.07442888489169129
| 3,376
|
membrane traffic protein
| 28
| 69
| 2.855923
| 0.004291
|
O60645,Q9NX40,Q96ED9,Q96RL7,Q00765,Q99523,P43307,P11717,Q9UQN3,P49257,O14976,Q96PC5,Q6NUK4,A6NIH7,Q9BXS5,O00429,Q9Y2T2,O60313,Q12768,P40855,P50570,Q9H6H4,Q13432,Q9HD26,P20645,Q9H4M9,Q9H9E3,P42566
|
Functions
|
Panther Protein class
|
panther_protein_class
|
387,264,522,146,798,668,34,542,824,679,676,178,695,52,716,826,720,329,335,591,730,478,104,501,374,639,250,755
|
52,2046,826,676,1511,1920,329,387,1669,2132,2915,2754,542,374,2185,2313,591,755,34,1980,679,730,1154,1070,3069,2237,798,1841,949,335,831,104,1385,1493,695,1949,1387,1169,1238,1496,3076,1596,522,178,1853,146,668,2666,1078,716,1245,1320,639,478,250,501,1109,1539,1959,264,1656,2041,3062,1251,824,939,1085,720,1086
|
2.8591098246251514,-0.2902048261296045,0.4085574264207841,0.565514082039327,-0.023598660010764588,-0.22710959688583782,1.1505511630774563,1.0163834713233377,-0.10377915671823269,-0.33281539857511017,-0.808862463451572,-0.6672254158451334,0.7327378977030797,1.046618985345816,-0.354287776657499,-0.41938548886236693,0.6667202646970376,0.47910021734806124,3.083627658114699,-0.2480332200865538,0.565514082039327,0.5138974074088837,0.17010849742073567,0.2264292404709339,-0.980321919952045,-0.37587289727828466,0.4439885391534624,-0.18558195150973228,0.3185486441921405,1.135880610204166,0.4085574264207841,2.3783860185520687,0.055014368762545285,-0.0038005361770060086,0.5483849475613088,-0.22710959688583782,0.055014368762545285,0.17010849742073567,0.1321121623528798,-0.0038005361770060086,-0.980321919952045,-0.0634896107921604,0.7653236556388097,1.7931876481313542,-0.18558195150973228,2.0071561264974758,0.5825675708995396,-0.5981577547393172,0.2264292404709339,0.5311795854762361,0.1321121623528798,0.09374950248621658,0.6164499083295459,0.8455870712937495,1.418723201036815,0.7976328933322394,0.2077445134366247,-0.023598660010764588,-0.22710959688583782,1.3776655599934584,-0.0835841298387108,-0.26906464190792506,-0.9554014328962437,0.1321121623528798,0.42631322556594947,0.3367165517731276,0.2264292404709339,0.5311795854762361,0.2264292404709339
| 3,376
|
Inorganic anion transport
| 9
| 25
| 2.855872
| 0.004292
|
Q9NW15,Q9Y277,P21796,P45880,Q9UHG3,Q9UBX3,P51798,P08183,Q9C0H2
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
362,231,8,11,17,83,311,216,63
|
881,1062,506,216,1187,8,2268,11,311,411,1300,1158,743,3356,1044,1500,63,1362,362,83,17,231,1658,2550,861
|
0.3548007225100377,0.2264292404709339,0.7815125855528189,1.5391760995751391,0.15115574181980668,3.555036482266552,-0.3975717877794668,3.4381474194828905,1.208658359818944,0.9705669749994547,0.09374950248621658,0.17010849742073567,0.4965378185069035,-2.699266327650186,0.2450260771368476,-0.0038005361770060086,2.7314251993438563,0.07442888489169129,1.0915175946894244,2.5595940969002076,3.3551325867531854,1.486136587048457,-0.0835841298387108,-0.5302135415922944,0.3907205059965324
| 3,376
|
Regulation of cellular ph
| 8
| 21
| 2.832888
| 0.004613
|
Q8N511,Q15904,O75503,Q9Y487,P61421,Q9HC07,P50897,Q93050
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
40,295,137,423,456,112,22,188
|
137,770,1220,1187,1222,1974,22,2318,456,1758,295,40,500,188,1906,112,1212,911,423,2550,861
|
2.0415749265642926,0.4615839958458578,0.1321121623528798,0.15115574181980668,0.1321121623528798,-0.2480332200865538,3.2302833584863713,-0.41938548886236693,0.8772224665898438,-0.14447423395217424,1.251645809202598,3.016205187599177,0.7976328933322394,1.7313649796578738,-0.20629282062173515,2.294602822374333,0.15115574181980668,0.3548007225100377,0.9551695312607196,-0.5302135415922944,0.3907205059965324
| 3,376
|
Regulation of ph
| 8
| 21
| 2.832888
| 0.004613
|
Q8N511,Q15904,O75503,Q9Y487,P61421,Q9HC07,P50897,Q93050
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
40,295,137,423,456,112,22,188
|
137,770,1220,1187,1222,1974,22,2318,456,1758,295,40,500,188,1906,112,1212,911,423,2550,861
|
2.0415749265642926,0.4615839958458578,0.1321121623528798,0.15115574181980668,0.1321121623528798,-0.2480332200865538,3.2302833584863713,-0.41938548886236693,0.8772224665898438,-0.14447423395217424,1.251645809202598,3.016205187599177,0.7976328933322394,1.7313649796578738,-0.20629282062173515,2.294602822374333,0.15115574181980668,0.3548007225100377,0.9551695312607196,-0.5302135415922944,0.3907205059965324
| 3,376
|
Amyloid precursor protein metabolic process
| 8
| 20
| 2.81877
| 0.004821
|
Q13464,Q9NQX7,Q9NQC3,P49840,Q92542,O75298,O95197,Q15392
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
322,105,106,364,400,366,30,191
|
1400,366,30,2092,1068,2489,485,364,1038,322,3041,1525,191,2105,400,1424,1207,106,105,1857
|
0.03550516234149863,1.0616453881949772,3.108547336875158,-0.31145474882693824,0.2264292404709339,-0.5078096934092219,0.8296696426224738,1.0766114520886294,0.2450260771368476,1.179718982402758,-0.9306254080954044,-0.023598660010764588,1.6937468932790258,-0.31145474882693824,0.9859014847349855,0.03550516234149863,0.15115574181980668,2.357634147809756,2.3783860185520687,-0.18558195150973228
| 3,376
|
Phospholipid binding
| 21
| 97
| 2.816717
| 0.004852
|
Q8WTV0,Q8N668,P21796,P45880,P04083,Q13045,Q8N3F8,P50897,O14773,Q14108,Q9UM22,Q9BWH2,Q9NZJ7,O60313,Q9NZD2,Q8NCC3,Q9H4A6,P07602,Q96L92,Q9Y4G8,Q9UKG1
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
130,390,8,11,393,399,275,22,25,37,43,312,444,329,210,85,213,333,348,373,371
|
1661,1966,2257,446,1737,25,1327,1664,2258,1511,3080,329,1547,555,646,1116,1401,393,2786,333,1441,1405,1029,1476,2136,2087,606,917,8,1750,2094,1933,11,2683,1885,2368,22,689,796,1225,1987,740,2530,399,3041,1807,1343,37,993,3246,869,3022,2330,2537,681,1950,2201,275,390,85,130,1354,1273,1564,1817,1458,348,1726,2539,1728,312,3239,1210,1362,878,213,1461,553,210,444,2041,1006,3309,1431,371,3112,43,1283,1324,1086,1735,1325,373,1144,825,1114,566
|
-0.10377915671823269,-0.2480332200865538,-0.3975717877794668,0.8929413902574874,-0.14447423395217424,3.190224570239214,0.07442888489169129,-0.10377915671823269,-0.3975717877794668,-0.023598660010764588,-1.0053883317133208,1.1505511630774563,-0.043494737915892735,0.7163400404236764,0.5995459898347874,0.18897117543040606,0.03550516234149863,1.0011735038559333,-0.6905032048336213,1.135880610204166,0.015900464346774338,0.03550516234149863,0.2450260771368476,-0.0038005361770060086,-0.33281539857511017,-0.31145474882693824,0.6500364914113959,0.3367165517731276,3.555036482266552,-0.14447423395217424,-0.31145474882693824,-0.22710959688583782,3.4381474194828905,-0.6210539026805592,-0.20629282062173515,-0.44131505481374056,3.2302833584863713,0.5483849475613088,0.4439885391534624,0.1321121623528798,-0.2480332200865538,0.4965378185069035,-0.5302135415922944,0.9859014847349855,-0.9306254080954044,-0.16497606147263494,0.07442888489169129,3.050094664845848,0.28195892039051096,-1.3725120489511942,0.372801821409757,-0.9059924038468624,-0.41938548886236693,-0.5302135415922944,0.565514082039327,-0.22710959688583782,-0.354287776657499,1.3361396976874031,1.0163834713233377,2.5497809452946028,2.0869404990527856,0.07442888489169129,0.11297700392516687,-0.043494737915892735,-0.16497606147263494,0.015900464346774338,1.1211517662256676,-0.12407556372432456,-0.5302135415922944,-0.12407556372432456,1.208658359818944,-1.3452365310224934,0.15115574181980668,0.07442888489169129,0.372801821409757,1.552314809182681,0.015900464346774338,0.7327378977030797,1.56540566205142,0.9085950944992713,-0.26906464190792506,0.28195892039051096,-1.7433267771566325,0.03550516234149863,1.0616453881949772,-1.0306021517672246,2.990550171469064,0.11297700392516687,0.09374950248621658,0.2264292404709339,-0.12407556372432456,0.09374950248621658,1.0616453881949772,0.18897117543040606,0.42631322556594947,0.2077445134366247,0.7163400404236764
| 3,376
|
Metapathway biotransformation phase i and ii
| 7
| 20
| 2.813842
| 0.004895
|
P07099,Q16850,Q8NCH0,Q6UW02,P78417,P21964,Q7LGA3
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
134,141,44,176,94,409,95
|
1867,1469,1519,134,1748,2402,2404,409,1930,1886,94,141,176,95,2871,44,437,1910,2773,1786
|
-0.20629282062173515,-0.0038005361770060086,-0.023598660010764588,2.0529722663918206,-0.14447423395217424,-0.4633615537366067,-0.4633615537366067,0.9705669749994547,-0.22710959688583782,-0.20629282062173515,2.470216891564265,2.030139933980146,1.7931876481313542,2.4398849348313916,-0.7611195948253038,2.973331959590957,0.9241840457318883,-0.20629282062173515,-0.6672254158451334,-0.14447423395217424
| 3,376
|
Endoplasmic reticulum golgi intermediate compartment membrane
| 15
| 27
| 2.8092
| 0.004966
|
Q9Y282,Q15363,Q8N511,Q15904,O15260,Q9BVK6,P49755,O95070,Q96GC9,Q9H0U4,Q969X5,Q03518,Q9Y3B3,Q10472,Q13190
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
97,5,40,295,39,332,485,204,144,599,339,334,57,285,474
|
39,1740,2131,204,3033,679,485,1154,1711,334,1841,285,831,474,5,295,40,339,144,1318,332,1361,599,97,615,57,3364
|
3.016205187599177,-0.14447423395217424,-0.33281539857511017,1.6043940725091548,-0.9306254080954044,0.565514082039327,0.8296696426224738,0.17010849742073567,-0.12407556372432456,1.135880610204166,-0.18558195150973228,1.3081910804853814,0.4085574264207841,0.8455870712937495,3.708771690562757,1.251645809202598,3.016205187599177,1.135880610204166,2.018667073067943,0.09374950248621658,1.1505511630774563,0.07442888489169129,0.6667202646970376,2.4398849348313916,0.6500364914113959,2.786761095827931,-3.8041340926168594
| 3,376
|
Blindness
| 17
| 79
| 2.807404
| 0.004994
|
P49770,P17900,P51798,Q9Y5P6,P06865,P00846,Q86Y39,Q96CU9,O96000,Q9H6K4,P07602,P50897,P53701,P03886,O43676,P16278,Q9NZ08
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
129,353,311,227,262,7,187,78,272,147,333,22,246,24,26,93,127
|
1662,482,1510,538,26,2398,1115,2049,367,1670,2752,3016,2853,272,2181,7,24,2638,2558,262,333,1185,2965,3135,93,353,2889,2089,918,2893,2947,2450,842,1976,1706,2230,1446,1299,129,3226,2453,22,311,1125,246,1069,2019,2274,692,2768,1488,1557,1641,1584,758,2197,2699,187,2875,2160,2112,932,712,1421,78,597,3125,2938,1210,147,613,1005,1249,127,444,3012,2474,227,721
|
-0.10377915671823269,0.8296696426224738,-0.023598660010764588,0.7327378977030797,3.1659423425394335,-0.4633615537366067,0.18897117543040606,-0.2902048261296045,1.0616453881949772,-0.10377915671823269,-0.6672254158451334,-0.9059924038468624,-0.7611195948253038,1.3361396976874031,-0.354287776657499,3.576464581247993,3.214321038100156,-0.5981577547393172,-0.552738738110152,1.3776655599934584,1.135880610204166,0.15115574181980668,-0.8571497916635558,-1.1071432230243936,2.470216891564265,1.1063642295621396,-0.784923636467135,-0.31145474882693824,0.3367165517731276,-0.784923636467135,-0.8329374006846979,-0.4855260677859258,0.3907205059965324,-0.2480332200865538,-0.12407556372432456,-0.37587289727828466,0.015900464346774338,0.09374950248621658,2.098189349032581,-1.3181298258671186,-0.4855260677859258,3.2302833584863713,1.208658359818944,0.18897117543040606,1.418723201036815,0.2264292404709339,-0.26906464190792506,-0.3975717877794668,0.5483849475613088,-0.6672254158451334,-0.0038005361770060086,-0.043494737915892735,-0.0835841298387108,-0.0634896107921604,0.47910021734806124,-0.354287776657499,-0.6210539026805592,1.7438162203898662,-0.7611195948253038,-0.33281539857511017,-0.31145474882693824,0.3367165517731276,0.5311795854762361,0.03550516234149863,2.5888606637088407,0.6667202646970376,-1.0559648852353496,-0.808862463451572,0.15115574181980668,2.0071561264974758,0.6500364914113959,0.28195892039051096,0.1321121623528798,2.1094015983677914,0.9085950944992713,-0.8815009988157699,-0.4855260677859258,1.4994697838784592,0.5311795854762361
| 3,376
|
Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins
| 14
| 69
| 2.80214
| 0.005076
|
P13073,P00846,Q9UDW1,P00403,Q86Y39,O96000,O95168,P24539,Q9P0J0,Q9P0S2,P03886,O14949,O43676,O75964
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
161,7,74,267,187,272,278,240,283,214,24,87,26,31
|
1618,1437,87,2716,26,1028,886,2049,367,1670,290,2134,31,278,704,2443,272,267,7,24,1220,1186,2012,161,3126,3145,1189,2889,793,918,754,240,2228,2947,2450,889,2143,3019,2837,2316,3086,3226,1015,1096,968,2019,2241,1344,925,2412,1895,781,187,2160,2112,420,1501,1459,2938,1462,613,1249,3012,283,214,74,3258,721,1215
|
-0.0835841298387108,0.015900464346774338,2.530067311521496,-0.6440760551569396,3.1659423425394335,0.2450260771368476,0.3548007225100377,-0.2902048261296045,1.0616453881949772,-0.10377915671823269,1.2941363054249848,-0.33281539857511017,3.091955963388661,1.322192093055503,0.5311795854762361,-0.4855260677859258,1.3361396976874031,1.3500342456184196,3.576464581247993,3.214321038100156,0.1321121623528798,0.15115574181980668,-0.26906464190792506,1.8659724939578621,-1.0814780591807345,-1.132961948971579,0.15115574181980668,-0.784923636467135,0.4439885391534624,0.3367165517731276,0.47910021734806124,1.445839319599628,-0.37587289727828466,-0.8329374006846979,-0.4855260677859258,0.3548007225100377,-0.33281539857511017,-0.9059924038468624,-0.7374490318787568,-0.41938548886236693,-1.0053883317133208,-1.3181298258671186,0.2635357357357556,0.2077445134366247,0.3002963271667747,-0.26906464190792506,-0.37587289727828466,0.07442888489169129,0.3367165517731276,-0.4633615537366067,-0.20629282062173515,0.4615839958458578,1.7438162203898662,-0.33281539857511017,-0.31145474882693824,0.9551695312607196,-0.0038005361770060086,0.015900464346774338,-0.808862463451572,0.015900464346774338,0.6500364914113959,0.1321121623528798,-0.8815009988157699,1.322192093055503,1.552314809182681,2.617870951389883,-1.3999582054993458,0.5311795854762361,0.15115574181980668
| 3,376
|
Sphingolipid metabolism
| 7
| 10
| 2.800462
| 0.005103
|
Q16739,P17900,Q06136,O95470,Q13510,P07602,P04062
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
64,353,98,265,111,333,90
|
491,1868,265,90,333,353,98,111,64,1464
|
0.8136850803085195,-0.20629282062173515,1.3638760848112592,2.4902865084460193,1.135880610204166,1.1063642295621396,2.429712971519325,2.315743939212719,2.7127698952516086,0.015900464346774338
| 3,376
|
Golgi organization
| 22
| 65
| 2.795723
| 0.005178
|
Q7Z3D4,O15027,Q15363,Q96GC9,Q9P2W9,P40616,O15260,P49257,O14976,Q9UL15,Q9Y3B3,O43752,Q9BVK6,Q8NHH9,Q96MW5,Q9H4A6,Q9Y3A6,Q13190,P49755,Q9BSR8,Q9H9E3,Q14999
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
259,627,5,144,29,544,39,679,676,445,57,200,332,208,736,213,615,474,485,638,250,383
|
2180,882,676,627,39,1572,200,1669,1622,2131,1119,1222,1974,1754,544,1412,1582,679,485,730,2235,1711,1229,1156,1197,1937,1841,831,474,2026,1718,383,5,1306,1454,2332,259,3043,2335,2873,2163,208,2981,1354,2465,144,1498,736,3011,3297,638,854,332,213,1461,1537,250,2040,29,880,445,3286,615,57,1368
|
-0.354287776657499,0.3548007225100377,0.565514082039327,0.6164499083295459,3.016205187599177,-0.0634896107921604,1.630152502007486,-0.10377915671823269,-0.0835841298387108,-0.33281539857511017,0.18897117543040606,0.1321121623528798,-0.2480332200865538,-0.14447423395217424,0.7327378977030797,0.03550516234149863,-0.0634896107921604,0.565514082039327,0.8296696426224738,0.5138974074088837,-0.37587289727828466,-0.12407556372432456,0.1321121623528798,0.17010849742073567,0.15115574181980668,-0.22710959688583782,-0.18558195150973228,0.4085574264207841,0.8455870712937495,-0.26906464190792506,-0.12407556372432456,1.0315318217278158,3.708771690562757,0.09374950248621658,0.015900464346774338,-0.41938548886236693,1.3914030126962775,-0.9306254080954044,-0.41938548886236693,-0.7611195948253038,-0.33281539857511017,1.56540566205142,-0.8571497916635558,0.07442888489169129,-0.4855260677859258,2.018667073067943,-0.0038005361770060086,0.5138974074088837,-0.8815009988157699,-1.6549680395922322,0.6164499083295459,0.3907205059965324,1.1505511630774563,1.552314809182681,0.015900464346774338,-0.023598660010764588,1.418723201036815,-0.26906464190792506,3.1414718652717917,0.372801821409757,0.9085950944992713,-1.5683244293101335,0.6500364914113959,2.786761095827931,0.07442888489169129
| 3,376
|
Protein transporter activity
| 8
| 14
| 2.795223
| 0.005186
|
O60830,Q9NS69,Q99595,Q9HD20,P49755,Q15388,Q07820,O14925
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
0,2,3,135,485,206,435,190
|
190,0,2305,557,485,2568,435,206,1310,3,135,2,719,737
|
1.6937468932790258,4.625302186087037,-0.41938548886236693,0.7163400404236764,0.8296696426224738,-0.552738738110152,0.9241840457318883,1.5784489587449075,0.09374950248621658,4.079811310189964,2.0529722663918206,4.3051831514783245,0.5311795854762361,0.5138974074088837
| 3,376
|
Arthritis
| 15
| 45
| 2.793777
| 0.00521
|
P10321,Q8WVQ1,Q14108,Q92890,O00170,P28070,Q14739,P04062,Q13510,Q96RL7,P06280,P51798,O75844,P21964,Q9NZ08
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
509,452,37,487,482,138,428,90,111,146,310,311,88,409,127
|
482,1398,807,1184,88,1549,2306,90,310,985,509,2013,677,409,2606,138,526,1299,1982,311,2320,2057,2492,2274,2568,2152,111,37,428,3088,2333,2032,452,2506,487,1565,804,146,717,2345,127,2987,1143,2300,3096
|
0.8296696426224738,0.03550516234149863,0.42631322556594947,0.15115574181980668,2.5201665300557425,-0.043494737915892735,-0.41938548886236693,2.4902865084460193,1.208658359818944,0.28195892039051096,0.7815125855528189,-0.26906464190792506,0.565514082039327,0.9705669749994547,-0.5753864237832664,2.0415749265642926,0.7490655969974919,0.09374950248621658,-0.2480332200865538,1.208658359818944,-0.41938548886236693,-0.2902048261296045,-0.5078096934092219,-0.3975717877794668,-0.552738738110152,-0.33281539857511017,2.315743939212719,3.050094664845848,0.9397087056445106,-1.0053883317133208,-0.41938548886236693,-0.26906464190792506,0.8929413902574874,-0.5078096934092219,0.8296696426224738,-0.043494737915892735,0.4439885391534624,2.0071561264974758,0.5311795854762361,-0.41938548886236693,2.1094015983677914,-0.8571497916635558,0.18897117543040606,-0.3975717877794668,-1.0053883317133208
| 3,376
|
Steroid metabolic process
| 15
| 68
| 2.793003
| 0.005222
|
Q8WTV0,P04035,O95470,Q14534,Q16850,P05067,Q13510,P38435,Q9H2C2,Q15800,Q99538,Q14849,P04062,O15118,Q15392
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
130,261,265,235,141,143,111,148,53,116,184,58,90,157,191
|
439,157,1217,1794,265,1404,261,90,628,143,3114,1292,965,2402,266,1094,1750,1254,2893,2895,2015,2268,1068,843,148,2922,2644,920,632,3292,1756,1802,2948,812,2653,2927,778,1303,111,2866,235,428,58,869,2284,191,1164,1203,116,141,513,1812,2202,130,3075,2205,1020,184,3125,2879,2540,53,402,2546,2121,837,2780,1007
|
0.9085950944992713,1.9136707952245202,0.1321121623528798,-0.16497606147263494,1.3638760848112592,0.03550516234149863,1.3776655599934584,2.4902865084460193,0.6164499083295459,2.018667073067943,-1.0559648852353496,0.09374950248621658,0.3002963271667747,-0.4633615537366067,1.3638760848112592,0.2077445134366247,-0.14447423395217424,0.11297700392516687,-0.784923636467135,-0.784923636467135,-0.26906464190792506,-0.3975717877794668,0.2264292404709339,0.3907205059965324,1.9956068751611455,-0.808862463451572,-0.5981577547393172,0.3367165517731276,0.6164499083295459,-1.6549680395922322,-0.14447423395217424,-0.16497606147263494,-0.8329374006846979,0.42631322556594947,-0.5981577547393172,-0.808862463451572,0.4615839958458578,0.09374950248621658,2.315743939212719,-0.7611195948253038,1.4593216736559882,0.9397087056445106,2.7684197758655547,0.372801821409757,-0.3975717877794668,1.6937468932790258,0.17010849742073567,0.15115574181980668,2.208698172161687,2.030139933980146,0.7815125855528189,-0.16497606147263494,-0.354287776657499,2.0869404990527856,-0.980321919952045,-0.354287776657499,0.2635357357357556,1.7685881177452407,-1.0559648852353496,-0.7611195948253038,-0.5302135415922944,2.8591098246251514,0.9859014847349855,-0.5302135415922944,-0.31145474882693824,0.4085574264207841,-0.6672254158451334,0.28195892039051096
| 3,376
|
Alzheimers disease
| 16
| 60
| 2.791126
| 0.005252
|
P13073,P00846,Q9UDW1,P07384,P49841,P00403,P05067,O96000,Q92542,O95168,P16615,P24539,O75306,O14949,O43676,P14406
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
161,7,74,394,330,267,143,272,400,278,302,240,367,87,26,62
|
1618,1437,87,2716,26,1028,2049,367,1670,2134,278,704,2443,272,267,7,2755,143,1220,394,1186,448,2012,161,62,1703,3145,1189,302,3268,2889,793,918,754,240,2228,1222,2947,1974,2450,889,2143,2489,2316,3086,1299,3226,330,1015,2019,1381,1198,1842,2412,1895,400,3125,74,1212,721
|
-0.0835841298387108,0.015900464346774338,2.530067311521496,-0.6440760551569396,3.1659423425394335,0.2450260771368476,-0.2902048261296045,1.0616453881949772,-0.10377915671823269,-0.33281539857511017,1.322192093055503,0.5311795854762361,-0.4855260677859258,1.3361396976874031,1.3500342456184196,3.576464581247993,-0.6672254158451334,2.018667073067943,0.1321121623528798,1.0011735038559333,0.15115574181980668,0.8929413902574874,-0.26906464190792506,1.8659724939578621,2.7407131538046365,-0.12407556372432456,-1.132961948971579,0.15115574181980668,1.2230433462408152,-1.4833391917688719,-0.784923636467135,0.4439885391534624,0.3367165517731276,0.47910021734806124,1.445839319599628,-0.37587289727828466,0.1321121623528798,-0.8329374006846979,-0.2480332200865538,-0.4855260677859258,0.3548007225100377,-0.33281539857511017,-0.5078096934092219,-0.41938548886236693,-1.0053883317133208,0.09374950248621658,-1.3181298258671186,1.1505511630774563,0.2635357357357556,-0.26906464190792506,0.055014368762545285,0.15115574181980668,-0.18558195150973228,-0.4633615537366067,-0.20629282062173515,0.9859014847349855,-1.0559648852353496,2.617870951389883,0.15115574181980668,0.5311795854762361
| 3,376
|
Proton transmembrane transport
| 7
| 44
| 2.782075
| 0.005401
|
P13073,Q13423,P00846,Q9UDW1,P24539,P12235,O75964
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
161,194,7,74,240,154,31
|
1618,1437,1699,1216,2049,2134,31,267,7,628,1118,1220,1186,2012,154,161,793,1123,2891,240,2228,2994,889,2143,1411,1798,2316,3086,1096,968,456,1300,194,1344,1386,2803,1208,1459,1138,489,74,1212,911,1431
|
-0.0835841298387108,0.015900464346774338,-0.12407556372432456,0.1321121623528798,-0.2902048261296045,-0.33281539857511017,3.091955963388661,1.3500342456184196,3.576464581247993,0.6164499083295459,0.18897117543040606,0.1321121623528798,0.15115574181980668,-0.26906464190792506,1.9607270744213334,1.8659724939578621,0.4439885391534624,0.18897117543040606,-0.784923636467135,1.445839319599628,-0.37587289727828466,-0.8815009988157699,0.3548007225100377,-0.33281539857511017,0.03550516234149863,-0.16497606147263494,-0.41938548886236693,-1.0053883317133208,0.2077445134366247,0.3002963271667747,0.8772224665898438,0.09374950248621658,1.6684451556620152,0.07442888489169129,0.055014368762545285,-0.6905032048336213,0.15115574181980668,0.015900464346774338,0.18897117543040606,0.8296696426224738,2.617870951389883,0.15115574181980668,0.3548007225100377,0.03550516234149863
| 3,376
|
Abc family proteins mediated transport
| 15
| 53
| 2.770434
| 0.005598
|
O75027,P61289,P49721,P25786,P25787,Q9UBV2,P28070,Q9BUN8,Q9UL46,Q14997,P20618,P28072,P49720,P08183,Q92530
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
289,450,99,543,263,296,138,430,503,211,239,179,244,216,384
|
701,2440,2808,1285,2301,1062,1330,289,1217,1090,1794,2051,216,1628,2054,239,543,263,2090,2720,1880,138,179,687,2015,2721,591,1296,1032,244,99,1481,2788,2148,810,450,1714,1523,1636,1382,1759,211,1941,2623,384,1134,2168,430,1732,1543,296,503,1545
|
0.5311795854762361,-0.4855260677859258,-0.7139106589140215,0.09374950248621658,-0.41938548886236693,0.2264292404709339,0.07442888489169129,1.2941363054249848,0.1321121623528798,0.2077445134366247,-0.16497606147263494,-0.2902048261296045,1.5391760995751391,-0.0835841298387108,-0.2902048261296045,1.445839319599628,0.7327378977030797,1.3776655599934584,-0.31145474882693824,-0.6440760551569396,-0.20629282062173515,2.0415749265642926,1.7809092990421234,0.5483849475613088,-0.26906464190792506,-0.6440760551569396,0.6667202646970376,0.09374950248621658,0.2450260771368476,1.4323066040977575,2.4195100841990267,-0.0038005361770060086,-0.6905032048336213,-0.33281539857511017,0.42631322556594947,0.8929413902574874,-0.12407556372432456,-0.023598660010764588,-0.0835841298387108,0.055014368762545285,-0.14447423395217424,1.552314809182681,-0.22710959688583782,-0.5753864237832664,1.0315318217278158,0.18897117543040606,-0.33281539857511017,0.9397087056445106,-0.12407556372432456,-0.023598660010764588,1.251645809202598,0.7976328933322394,-0.023598660010764588
| 3,376
|
Intracellular protein transmembrane transport
| 12
| 25
| 2.758427
| 0.005808
|
O60830,Q99595,O43933,P31751,Q15388,Q15629,O96008,O75298,P50542,Q99442,O43615,O14925
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
0,3,539,232,206,50,557,366,382,476,405,190
|
190,405,539,0,366,2305,1372,557,2967,1746,232,382,3069,2020,2568,206,50,833,1950,2422,624,476,3,1856,719
|
1.6937468932790258,0.9705669749994547,0.7327378977030797,4.625302186087037,1.0616453881949772,-0.41938548886236693,0.055014368762545285,0.7163400404236764,-0.8571497916635558,-0.14447423395217424,1.4727539894057913,1.0315318217278158,-0.980321919952045,-0.26906464190792506,-0.552738738110152,1.5784489587449075,2.8946877773816957,0.4085574264207841,-0.22710959688583782,-0.4633615537366067,0.6332798897464621,0.8455870712937495,4.079811310189964,-0.18558195150973228,0.5311795854762361
| 3,376
|
ER-Golgi transport
| 17
| 51
| 2.753099
| 0.005903
|
P49069,Q9Y282,O14579,Q15436,O15027,Q15363,P49755,Q9HCU5,O95249,Q6NUQ1,Q9NR31,O95070,Q8IUR0,Q969X5,P84085,Q9P2W9,O95197
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
569,97,657,486,627,5,485,328,201,229,625,204,307,339,592,29,30
|
657,627,1740,1572,3196,1669,2131,1514,204,30,201,2221,2482,1030,2449,1191,1836,569,679,485,1154,2813,2320,2057,1070,1711,2925,1229,592,2496,5,486,3072,1385,229,2332,307,931,1313,1496,339,1318,2666,328,625,1049,29,2076,97,939,1026
|
0.5825675708995396,0.6164499083295459,-0.14447423395217424,-0.0634896107921604,-1.2378047400733483,-0.10377915671823269,-0.33281539857511017,-0.023598660010764588,1.6043940725091548,3.108547336875158,1.630152502007486,-0.37587289727828466,-0.5078096934092219,0.2450260771368476,-0.4855260677859258,0.15115574181980668,-0.18558195150973228,0.6998715023470454,0.565514082039327,0.8296696426224738,0.17010849742073567,-0.7139106589140215,-0.41938548886236693,-0.2902048261296045,0.2264292404709339,-0.12407556372432456,-0.808862463451572,0.1321121623528798,0.6667202646970376,-0.5078096934092219,3.708771690562757,0.8296696426224738,-0.980321919952045,0.055014368762545285,1.486136587048457,-0.41938548886236693,1.2230433462408152,0.3367165517731276,0.09374950248621658,-0.0038005361770060086,1.135880610204166,0.09374950248621658,-0.5981577547393172,1.1651638225306005,0.6332798897464621,0.2450260771368476,3.1414718652717917,-0.2902048261296045,2.4398849348313916,0.3367165517731276,0.2635357357357556
| 3,376
|
G alpha i signalling events
| 10
| 24
| 2.749802
| 0.005963
|
Q9NRV9,O43865,P10644,P30154,P63218,P04083,P30153,P05067,P07602,Q9NZJ7
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
160,386,317,198,457,393,268,143,333,444
|
386,393,1373,143,333,1443,317,1747,2447,1829,1974,268,198,648,3149,1485,457,1381,1198,528,2193,160,444,1395
|
1.0163834713233377,1.0011735038559333,0.055014368762545285,2.018667073067943,1.135880610204166,0.015900464346774338,1.179718982402758,-0.14447423395217424,-0.4855260677859258,-0.18558195150973228,-0.2480332200865538,1.3500342456184196,1.6429624336734927,0.5995459898347874,-1.132961948971579,-0.0038005361770060086,0.8772224665898438,0.055014368762545285,0.15115574181980668,0.7490655969974919,-0.354287776657499,1.8779580865773922,0.9085950944992713,0.055014368762545285
| 3,376
|
Nucleobase containing compound transmembrane transporter activity
| 8
| 15
| 2.74108
| 0.006124
|
Q9H2D1,Q8TB61,Q86VD7,Q6KCM7,Q9HC21,P12236,P12235,Q9BSK2
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
42,109,177,212,438,497,154,28
|
589,1062,2009,1118,154,497,2722,1482,212,780,177,109,28,42,438
|
0.6667202646970376,0.2264292404709339,-0.26906464190792506,0.18897117543040606,1.9607270744213334,0.7976328933322394,-0.6440760551569396,-0.0038005361770060086,1.552314809182681,0.4615839958458578,1.7931876481313542,2.3262652314834207,3.1496497632836333,2.990550171469064,0.9241840457318883
| 3,376
|
Nonalcoholic fatty liver disease
| 14
| 54
| 2.736425
| 0.006211
|
P13073,Q9UDW1,P49841,P31751,P00403,Q86Y39,P49840,Q96GC9,O96000,O95168,Q9P0J0,O14949,O43676,P14406
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
161,74,330,232,267,187,364,144,272,278,283,87,26,62
|
1618,1437,87,2716,26,1028,2049,367,1670,278,704,2443,272,267,2051,1186,2012,161,62,3145,1189,2889,1094,793,918,754,2947,2450,232,889,2489,2316,1299,3226,364,330,1015,545,2019,2235,1804,3104,1303,2933,2412,1895,187,144,980,1249,283,74,3258,721
|
-0.0835841298387108,0.015900464346774338,2.530067311521496,-0.6440760551569396,3.1659423425394335,0.2450260771368476,-0.2902048261296045,1.0616453881949772,-0.10377915671823269,1.322192093055503,0.5311795854762361,-0.4855260677859258,1.3361396976874031,1.3500342456184196,-0.2902048261296045,0.15115574181980668,-0.26906464190792506,1.8659724939578621,2.7407131538046365,-1.132961948971579,0.15115574181980668,-0.784923636467135,0.2077445134366247,0.4439885391534624,0.3367165517731276,0.47910021734806124,-0.8329374006846979,-0.4855260677859258,1.4727539894057913,0.3548007225100377,-0.5078096934092219,-0.41938548886236693,0.09374950248621658,-1.3181298258671186,1.0766114520886294,1.1505511630774563,0.2635357357357556,0.7327378977030797,-0.26906464190792506,-0.37587289727828466,-0.16497606147263494,-1.0306021517672246,0.09374950248621658,-0.808862463451572,-0.4633615537366067,-0.20629282062173515,1.7438162203898662,2.018667073067943,0.3002963271667747,0.1321121623528798,1.322192093055503,2.617870951389883,-1.3999582054993458,0.5311795854762361
| 3,376
|
Intra golgi and retrograde golgi to er traffic
| 26
| 99
| 2.734813
| 0.006242
|
Q13561,Q15363,Q86Y91,Q10472,Q9P2W9,P40616,P11717,O15260,O60499,Q15836,Q9Y3B3,O43752,O95249,Q9BVK6,Q9H0U4,O00461,Q5VZE5,O75935,Q13190,Q6NUQ1,P49755,Q9H2M9,Q9UJW0,Q02224,P20645,Q9H9E3
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
388,5,389,285,29,544,542,39,41,436,57,200,201,332,599,80,84,222,474,229,485,365,502,498,374,250
|
1965,80,657,39,1740,1620,1572,200,2359,41,863,2131,222,1515,2480,201,1874,542,1030,2449,374,1257,2921,1191,544,2231,1980,2096,919,1836,485,2056,1125,989,796,2813,2320,1070,811,2925,1229,1340,892,923,1197,592,498,2767,1036,1199,285,2688,474,3105,388,1232,1040,2615,3088,2283,1682,5,436,1493,84,229,389,2873,931,872,1354,2664,1498,736,2384,2587,2666,1359,1693,332,1567,958,1362,599,365,250,2070,1429,982,2176,1049,29,2076,880,502,57,1736,1026,1009
|
-0.2480332200865538,2.5693783360444082,0.5825675708995396,3.016205187599177,-0.14447423395217424,-0.0835841298387108,-0.0634896107921604,1.630152502007486,-0.44131505481374056,3.007676347681497,0.372801821409757,-0.33281539857511017,1.5127538943193948,-0.023598660010764588,-0.5078096934092219,1.630152502007486,-0.20629282062173515,0.7327378977030797,0.2450260771368476,-0.4855260677859258,1.046618985345816,0.11297700392516687,-0.808862463451572,0.15115574181980668,0.7327378977030797,-0.37587289727828466,-0.2480332200865538,-0.31145474882693824,0.3367165517731276,-0.18558195150973228,0.8296696426224738,-0.2902048261296045,0.18897117543040606,0.28195892039051096,0.4439885391534624,-0.7139106589140215,-0.41938548886236693,0.2264292404709339,0.42631322556594947,-0.808862463451572,0.1321121623528798,0.07442888489169129,0.3548007225100377,0.3367165517731276,0.15115574181980668,0.6667202646970376,0.7976328933322394,-0.6672254158451334,0.2450260771368476,0.15115574181980668,1.3081910804853814,-0.6210539026805592,0.8455870712937495,-1.0306021517672246,1.0163834713233377,0.1321121623528798,0.2450260771368476,-0.5753864237832664,-1.0053883317133208,-0.3975717877794668,-0.10377915671823269,3.708771690562757,0.9241840457318883,-0.0038005361770060086,2.5497809452946028,1.486136587048457,1.0163834713233377,-0.7611195948253038,0.3367165517731276,0.372801821409757,0.07442888489169129,-0.5981577547393172,-0.0038005361770060086,0.5138974074088837,-0.44131505481374056,-0.552738738110152,-0.5981577547393172,0.07442888489169129,-0.10377915671823269,1.1505511630774563,-0.043494737915892735,0.3185486441921405,0.07442888489169129,0.6667202646970376,1.0766114520886294,1.418723201036815,-0.2902048261296045,0.03550516234149863,0.3002963271667747,-0.33281539857511017,0.2450260771368476,3.1414718652717917,-0.2902048261296045,0.372801821409757,0.7976328933322394,2.786761095827931,-0.12407556372432456,0.2635357357357556,0.28195892039051096
| 3,376
|
Secondary alcohol metabolic process
| 11
| 41
| 2.734513
| 0.006247
|
Q8WTV0,P04035,Q14534,Q16850,P05067,Q9H2C2,Q15800,Q14849,P04062,O15118,Q15392
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
130,261,235,141,143,53,116,58,90,157,191
|
157,2398,1217,3066,1794,1404,261,90,143,1292,965,266,2893,1068,843,2644,920,3341,632,2453,1802,2948,812,2653,2927,1303,2866,235,428,58,869,2284,191,1203,116,141,130,2907,53,2546,2121
|
1.9136707952245202,-0.4633615537366067,0.1321121623528798,-0.980321919952045,-0.16497606147263494,0.03550516234149863,1.3776655599934584,2.4902865084460193,2.018667073067943,0.09374950248621658,0.3002963271667747,1.3638760848112592,-0.784923636467135,0.2264292404709339,0.3907205059965324,-0.5981577547393172,0.3367165517731276,-2.3468748883404933,0.6164499083295459,-0.4855260677859258,-0.16497606147263494,-0.8329374006846979,0.42631322556594947,-0.5981577547393172,-0.808862463451572,0.09374950248621658,-0.7611195948253038,1.4593216736559882,0.9397087056445106,2.7684197758655547,0.372801821409757,-0.3975717877794668,1.6937468932790258,0.15115574181980668,2.208698172161687,2.030139933980146,2.0869404990527856,-0.784923636467135,2.8591098246251514,-0.5302135415922944,-0.31145474882693824
| 3,376
|
calmodulin-related
| 10
| 14
| 2.734012
| 0.006257
|
Q8IYU8,O43852,P0DP25,P80303,Q9BPX6,P41208,Q02818,Q14257,P60903,Q9BRK5
|
Functions
|
Panther Protein class
|
panther_protein_class
|
834,472,448,4,654,168,242,189,757,255
|
472,448,1445,865,168,757,4,242,189,1267,834,1534,654,255
|
0.8455870712937495,0.8929413902574874,0.015900464346774338,0.372801821409757,1.829768258961035,0.47910021734806124,3.8158495588954837,1.445839319599628,1.706330585324128,0.11297700392516687,0.4085574264207841,-0.023598660010764588,0.5995459898347874,1.4050887812930244
| 3,376
|
Respiratory chain
| 11
| 35
| 2.730069
| 0.006332
|
Q9UDW1,P00403,Q86Y39,Q96CU9,O96000,O95168,Q9P0J0,O14949,P03886,O43676,Q6DKK2
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
74,267,187,78,272,278,283,87,24,26,253
|
1618,87,2716,26,1028,2049,367,1670,278,704,2443,272,267,24,1186,3145,2889,754,2947,889,2316,3226,1015,2019,2412,1895,253,187,78,1249,283,74,3258,1178,721
|
-0.0835841298387108,2.530067311521496,-0.6440760551569396,3.1659423425394335,0.2450260771368476,-0.2902048261296045,1.0616453881949772,-0.10377915671823269,1.322192093055503,0.5311795854762361,-0.4855260677859258,1.3361396976874031,1.3500342456184196,3.214321038100156,0.15115574181980668,-1.132961948971579,-0.784923636467135,0.47910021734806124,-0.8329374006846979,0.3548007225100377,-0.41938548886236693,-1.3181298258671186,0.2635357357357556,-0.26906464190792506,-0.4633615537366067,-0.20629282062173515,1.4050887812930244,1.7438162203898662,2.5888606637088407,0.1321121623528798,1.322192093055503,2.617870951389883,-1.3999582054993458,0.17010849742073567,0.5311795854762361
| 3,376
|
Mitochondrial nucleotide transporter subfamily
| 7
| 11
| 2.728991
| 0.006353
|
Q9H2D1,Q70HW3,Q86VD7,Q6KCM7,Q9HC21,P12235,Q9BSK2
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
42,113,177,212,438,154,28
|
2009,1118,154,497,212,780,113,177,28,42,438
|
-0.26906464190792506,0.18897117543040606,1.9607270744213334,0.7976328933322394,1.552314809182681,0.4615839958458578,2.262642140545865,1.7931876481313542,3.1496497632836333,2.990550171469064,0.9241840457318883
| 3,376
|
transporter
| 24
| 57
| 2.727169
| 0.006388
|
O43681,O60830,Q99595,Q8N1F7,P52292,Q9H2V7,O00410,P53007,Q9NR77,Q9Y619,O43615,Q9H2D1,O43772,P55060,Q567V2,Q99805,P53985,Q9C0E2,Q6PML9,Q8TEX9,Q15070,O15397,Q92544,Q9HD45
|
Functions
|
Panther Protein class
|
panther_protein_class
|
506,0,3,532,648,142,768,773,153,675,405,42,432,690,60,196,199,341,594,623,243,616,500,122
|
768,1399,2961,3169,2637,616,405,506,432,1575,2811,0,1970,1150,2643,1933,2722,2368,3210,648,1259,1801,773,199,690,1227,2568,1037,1894,243,60,3356,594,1813,532,1390,2423,623,500,802,1132,1424,1135,3,196,2467,341,42,142,1538,122,153,1570,2296,1431,840,675
|
0.4615839958458578,0.03550516234149863,-0.8571497916635558,-1.185066492546918,-0.5981577547393172,0.6332798897464621,0.9705669749994547,0.7815125855528189,0.9241840457318883,-0.0634896107921604,-0.7139106589140215,4.625302186087037,-0.2480332200865538,0.17010849742073567,-0.5981577547393172,-0.22710959688583782,-0.6440760551569396,-0.44131505481374056,-1.2644156881924795,0.5995459898347874,0.11297700392516687,-0.16497606147263494,0.4615839958458578,1.6429624336734927,0.5483849475613088,0.1321121623528798,-0.552738738110152,0.2450260771368476,-0.20629282062173515,1.445839319599628,2.7684197758655547,-2.699266327650186,0.6667202646970376,-0.16497606147263494,0.7490655969974919,0.055014368762545285,-0.4633615537366067,0.6332798897464621,0.7976328933322394,0.4439885391534624,0.18897117543040606,0.03550516234149863,0.18897117543040606,4.079811310189964,1.6684451556620152,-0.4855260677859258,1.135880610204166,2.990550171469064,2.030139933980146,-0.023598660010764588,2.1649209674192837,1.9723925727598306,-0.043494737915892735,-0.3975717877794668,0.03550516234149863,0.4085574264207841,0.5825675708995396
| 3,376
|
Carbohydrate derivative transport
| 11
| 20
| 2.725866
| 0.006413
|
Q8WTV0,Q8TB61,Q86VD7,Q9NZD2,Q6KCM7,P07602,Q9HC21,P12236,L0R6Q1,Q9NZJ7,P12235
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
130,109,177,210,212,333,438,497,589,444,154
|
589,1062,2009,1118,333,154,497,2722,812,621,212,780,177,109,1044,130,979,438,210,444
|
0.6667202646970376,0.2264292404709339,-0.26906464190792506,0.18897117543040606,1.135880610204166,1.9607270744213334,0.7976328933322394,-0.6440760551569396,0.42631322556594947,0.6332798897464621,1.552314809182681,0.4615839958458578,1.7931876481313542,2.3262652314834207,0.2450260771368476,2.0869404990527856,0.3002963271667747,0.9241840457318883,1.56540566205142,0.9085950944992713
| 3,376
|
Organophosphate ester transmembrane transporter activity
| 7
| 13
| 2.706695
| 0.006796
|
Q9H2D1,Q8TB61,Q86VD7,Q6KCM7,Q9HC21,P12235,Q9BSK2
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
42,109,177,212,438,154,28
|
1062,2009,1118,154,497,2722,212,780,177,109,28,42,438
|
0.2264292404709339,-0.26906464190792506,0.18897117543040606,1.9607270744213334,0.7976328933322394,-0.6440760551569396,1.552314809182681,0.4615839958458578,1.7931876481313542,2.3262652314834207,3.1496497632836333,2.990550171469064,0.9241840457318883
| 3,376
|
Nucleotide transmembrane transporter activity
| 7
| 13
| 2.706695
| 0.006796
|
Q9H2D1,Q8TB61,Q86VD7,Q6KCM7,Q9HC21,P12235,Q9BSK2
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
42,109,177,212,438,154,28
|
1062,2009,1118,154,497,2722,212,780,177,109,28,42,438
|
0.2264292404709339,-0.26906464190792506,0.18897117543040606,1.9607270744213334,0.7976328933322394,-0.6440760551569396,1.552314809182681,0.4615839958458578,1.7931876481313542,2.3262652314834207,3.1496497632836333,2.990550171469064,0.9241840457318883
| 3,376
|
Vacuolar transport
| 20
| 55
| 2.70398
| 0.006851
|
A5D8V6,Q9P253,Q96ED9,O75351,Q96RL7,Q9H9H4,Q99523,O15118,Q7Z3T8,Q14108,P11717,O14976,Q9NZJ7,Q9UNK0,P46934,P61421,P07602,Q96L92,P11279,P20645
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
379,656,522,647,146,415,668,157,681,37,542,676,444,575,193,456,333,348,356,374
|
379,2046,2961,1327,676,157,1511,1920,647,333,2136,356,542,374,193,2318,988,2148,456,37,2693,1493,1590,1847,681,1949,2873,1689,1564,1906,522,348,1853,146,668,2207,2067,1078,805,1320,415,1109,1539,3111,1049,444,1656,656,2041,880,1396,575,824,720,1086
|
1.0315318217278158,-0.2902048261296045,-0.8571497916635558,0.07442888489169129,0.565514082039327,1.9136707952245202,-0.023598660010764588,-0.22710959688583782,0.5995459898347874,1.135880610204166,-0.33281539857511017,1.0915175946894244,0.7327378977030797,1.046618985345816,1.6811185084368743,-0.41938548886236693,0.28195892039051096,-0.33281539857511017,0.8772224665898438,3.050094664845848,-0.6210539026805592,-0.0038005361770060086,-0.0634896107921604,-0.18558195150973228,0.565514082039327,-0.22710959688583782,-0.7611195948253038,-0.10377915671823269,-0.043494737915892735,-0.20629282062173515,0.7653236556388097,1.1211517662256676,-0.18558195150973228,2.0071561264974758,0.5825675708995396,-0.354287776657499,-0.2902048261296045,0.2264292404709339,0.4439885391534624,0.09374950248621658,0.9705669749994547,0.2077445134366247,-0.023598660010764588,-1.0306021517672246,0.2450260771368476,0.9085950944992713,-0.0835841298387108,0.5995459898347874,-0.26906464190792506,0.372801821409757,0.055014368762545285,0.6998715023470454,0.42631322556594947,0.5311795854762361,0.2264292404709339
| 3,376
|
Sphingolipid metabolism overview
| 7
| 9
| 2.70344
| 0.006863
|
Q16739,Q06136,Q9NRA0,Q96G23,O95470,Q13510,O15121
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
64,98,489,167,265,111,123
|
123,491,1868,265,98,111,64,167,489
|
2.1428207883227306,0.8136850803085195,-0.20629282062173515,1.3638760848112592,2.429712971519325,2.315743939212719,2.7127698952516086,1.8418778252097934,0.8296696426224738
| 3,376
|
Sphingolipid metabolism integrated pathway
| 7
| 9
| 2.70344
| 0.006863
|
Q16739,Q06136,Q9NRA0,Q96G23,O95470,Q13510,O15121
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
64,98,489,167,265,111,123
|
123,491,1868,265,98,111,64,167,489
|
2.1428207883227306,0.8136850803085195,-0.20629282062173515,1.3638760848112592,2.429712971519325,2.315743939212719,2.7127698952516086,1.8418778252097934,0.8296696426224738
| 3,376
|
Golgi apparatus
| 116
| 335
| 2.70242
| 0.006884
|
P10321,O15126,P80303,Q15363,Q96ED9,Q8NBN3,Q9NPR9,Q8N4V1,P50897,P35670,O14773,Q9P2W9,O95197,P40616,O43505,Q14108,P11717,O15260,O60499,Q8NCH0,Q9H2C2,Q9NTJ5,Q9Y3B3,Q9UNK0,Q16739,Q5VW38,O00461,Q8IV08,Q9H0U4,Q9BSL1,P84085,L0R6Q1,P04062,Q9Y3A6,P16278,Q7LGA3,Q6ZRP7,Q9Y282,Q10713,Q68CQ7,Q9NR31,Q9NQX7,Q8TB61,Q9HC07,Q9BSR8,Q9UNK9,Q92520,Q13033,P05023,O14735,O15027,O75503,P52292,P05067,Q96RL7,Q9UJX6,Q99523,Q96K37,O15118,Q9UQB8,O14579,Q8IZA0,Q9Y371,P49257,Q93050,Q15392,Q99640,P46934,Q99805,O43752,O95249,O95070,Q9H4A6,Q8NDZ4,Q9C0D9,Q7Z5K2,Q8NBZ7,Q02818,Q9H9E3,Q9BRK5,P35613,Q7Z3D4,Q9NX40,P04439,Q8N3F8,Q10472,Q8IUR0,P06280,Q13464,Q9BVK6,Q969X5,Q96A57,P20645,P50542,Q14999,Q9Y3A3,O60645,Q9BXS4,P57737,Q92542,Q9H3P7,P11166,Q15836,Q8WVQ1,Q9H7Z7,Q9UBF8,Q8NF37,Q9BUR5,Q13190,O43852,Q15436,P49755,P20337,Q9HD26,Q92544,Q9Y3E0
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
509,505,4,5,522,12,14,19,22,526,25,29,30,544,538,37,542,39,41,44,53,572,57,575,64,65,80,81,599,598,592,589,90,615,93,95,611,97,608,100,625,105,109,112,638,643,125,633,628,626,627,137,648,143,146,673,668,667,157,159,657,164,685,679,188,191,192,193,196,200,201,204,213,217,221,223,224,242,250,255,256,259,264,273,275,285,307,310,322,332,339,347,374,382,383,385,387,397,396,400,402,408,436,452,459,469,464,477,474,472,486,485,492,501,500,517
|
589,2046,1966,826,2257,80,2180,657,2961,626,882,25,1619,676,627,157,505,885,914,39,1740,3302,538,3196,1920,200,3080,887,472,41,1741,387,863,1669,1622,2131,137,2304,3016,204,30,1515,201,2050,724,1516,1873,1874,2754,90,273,628,143,310,3353,1443,1876,2966,1187,509,408,542,93,3268,2088,1030,492,2449,374,3097,3199,1750,1973,1222,3033,1974,3243,2140,2186,1633,2921,1191,256,526,1705,1706,1754,544,1224,1412,1980,193,1836,2368,679,1299,485,1522,382,730,1982,22,2318,2056,2523,1154,988,648,1800,796,1225,2813,2320,396,1016,2235,2611,1711,797,1677,2925,3227,2188,3342,1229,1556,1804,4,1197,592,1262,2100,2152,1937,242,2864,1841,1199,285,949,608,1159,1890,831,1038,633,474,3332,322,3041,1343,1940,2496,37,1892,2693,993,2456,1718,3246,383,2617,869,2283,2900,5,191,486,1345,436,64,2105,732,1493,1454,65,2460,2415,3192,100,1590,2503,1417,1847,1307,1766,2869,1686,611,3164,95,2332,259,3043,223,2335,1592,2735,1949,871,1387,307,81,2873,952,164,275,734,19,931,12,224,44,2163,217,2110,464,109,872,3177,1313,452,1851,125,1354,400,500,2465,2624,188,1565,1904,1691,339,902,347,522,1498,667,1019,1001,1773,736,146,1318,1500,1133,1020,668,1649,192,2429,196,3011,3297,3247,255,598,638,854,1171,477,332,2511,1650,2909,1820,397,716,856,1502,221,1653,599,805,53,402,1778,213,459,1537,250,1855,112,501,2070,14,105,2746,625,982,572,264,823,1173,1857,2435,909,29,2076,469,1212,880,1367,1611,673,1006,3309,3219,3344,2547,2826,3014,575,643,3286,3062,1734,159,1785,97,939,1862,720,1787,685,385,615,57,517,3195,825,1114,1026,1368
|
0.6667202646970376,-0.2902048261296045,-0.2480332200865538,0.4085574264207841,-0.3975717877794668,2.5693783360444082,-0.354287776657499,0.5825675708995396,-0.8571497916635558,0.6164499083295459,0.3548007225100377,3.190224570239214,-0.0835841298387108,0.565514082039327,0.6164499083295459,1.9136707952245202,0.7815125855528189,0.3548007225100377,0.3367165517731276,3.016205187599177,-0.14447423395217424,-1.7433267771566325,0.7327378977030797,-1.2378047400733483,-0.22710959688583782,1.630152502007486,-1.0053883317133208,0.3548007225100377,0.8455870712937495,3.007676347681497,-0.14447423395217424,1.0163834713233377,0.372801821409757,-0.10377915671823269,-0.0835841298387108,-0.33281539857511017,2.0415749265642926,-0.41938548886236693,-0.9059924038468624,1.6043940725091548,3.108547336875158,-0.023598660010764588,1.630152502007486,-0.2902048261296045,0.5138974074088837,-0.023598660010764588,-0.20629282062173515,-0.20629282062173515,-0.6672254158451334,2.4902865084460193,1.3361396976874031,0.6164499083295459,2.018667073067943,1.208658359818944,-2.699266327650186,0.015900464346774338,-0.20629282062173515,-0.8571497916635558,0.15115574181980668,0.7815125855528189,0.9705669749994547,0.7327378977030797,2.470216891564265,-1.4833391917688719,-0.31145474882693824,0.2450260771368476,0.8136850803085195,-0.4855260677859258,1.046618985345816,-1.0306021517672246,-1.2378047400733483,-0.14447423395217424,-0.2480332200865538,0.1321121623528798,-0.9306254080954044,-0.2480332200865538,-1.3725120489511942,-0.33281539857511017,-0.354287776657499,-0.0835841298387108,-0.808862463451572,0.15115574181980668,1.3914030126962775,0.7490655969974919,-0.12407556372432456,-0.12407556372432456,-0.14447423395217424,0.7327378977030797,0.1321121623528798,0.03550516234149863,-0.2480332200865538,1.6811185084368743,-0.18558195150973228,-0.44131505481374056,0.565514082039327,0.09374950248621658,0.8296696426224738,-0.023598660010764588,1.0315318217278158,0.5138974074088837,-0.2480332200865538,3.2302833584863713,-0.41938548886236693,-0.2902048261296045,-0.5302135415922944,0.17010849742073567,0.28195892039051096,0.5995459898347874,-0.16497606147263494,0.4439885391534624,0.1321121623528798,-0.7139106589140215,-0.41938548886236693,1.0011735038559333,0.2635357357357556,-0.37587289727828466,-0.5753864237832664,-0.12407556372432456,0.4439885391534624,-0.10377915671823269,-0.808862463451572,-1.3181298258671186,-0.354287776657499,-2.3468748883404933,0.1321121623528798,-0.043494737915892735,-0.16497606147263494,3.8158495588954837,0.15115574181980668,0.6667202646970376,0.11297700392516687,-0.31145474882693824,-0.33281539857511017,-0.22710959688583782,1.445839319599628,-0.7611195948253038,-0.18558195150973228,0.15115574181980668,1.3081910804853814,0.3185486441921405,0.6500364914113959,0.17010849742073567,-0.20629282062173515,0.4085574264207841,0.2450260771368476,0.6164499083295459,0.8455870712937495,-2.0510303449211693,1.179718982402758,-0.9306254080954044,0.07442888489169129,-0.22710959688583782,-0.5078096934092219,3.050094664845848,-0.20629282062173515,-0.6210539026805592,0.28195892039051096,-0.4855260677859258,-0.12407556372432456,-1.3725120489511942,1.0315318217278158,-0.5753864237832664,0.372801821409757,-0.3975717877794668,-0.784923636467135,3.708771690562757,1.6937468932790258,0.8296696426224738,0.07442888489169129,0.9241840457318883,2.7127698952516086,-0.31145474882693824,0.5138974074088837,-0.0038005361770060086,0.015900464346774338,2.703402284279324,-0.4855260677859258,-0.4633615537366067,-1.2113555724853857,2.4195100841990267,-0.0634896107921604,-0.5078096934092219,0.03550516234149863,-0.18558195150973228,0.09374950248621658,-0.14447423395217424,-0.7611195948253038,-0.10377915671823269,0.6500364914113959,-1.1589358324480967,2.4398849348313916,-0.41938548886236693,1.3914030126962775,-0.9306254080954044,1.5127538943193948,-0.41938548886236693,-0.0634896107921604,-0.6440760551569396,-0.22710959688583782,0.372801821409757,0.055014368762545285,1.2230433462408152,2.5693783360444082,-0.7611195948253038,0.3185486441921405,1.8539458215110518,1.3361396976874031,0.5138974074088837,3.261966421590314,0.3367165517731276,3.4381474194828905,1.5127538943193948,2.973331959590957,-0.33281539857511017,1.5391760995751391,-0.31145474882693824,0.8614378522891492,2.3262652314834207,0.372801821409757,-1.185066492546918,0.09374950248621658,0.8929413902574874,-0.18558195150973228,2.120577452455775,0.07442888489169129,0.9859014847349855,0.7976328933322394,-0.4855260677859258,-0.5753864237832664,1.7313649796578738,-0.043494737915892735,-0.20629282062173515,-0.10377915671823269,1.135880610204166,0.3548007225100377,1.1211517662256676,0.7653236556388097,-0.0038005361770060086,0.5825675708995396,0.2635357357357556,0.28195892039051096,-0.14447423395217424,0.5138974074088837,2.0071561264974758,0.09374950248621658,-0.0038005361770060086,0.18897117543040606,0.2635357357357556,0.5825675708995396,-0.0835841298387108,1.6937468932790258,-0.4633615537366067,1.6684451556620152,-0.8815009988157699,-1.6549680395922322,-1.3725120489511942,1.4050887812930244,0.6667202646970376,0.6164499083295459,0.3907205059965324,0.17010849742073567,0.8455870712937495,1.1505511630774563,-0.5078096934092219,-0.0835841298387108,-0.784923636467135,-0.16497606147263494,1.0011735038559333,0.5311795854762361,0.3907205059965324,-0.0038005361770060086,1.5259892299575761,-0.0835841298387108,0.6667202646970376,0.4439885391534624,2.8591098246251514,0.9859014847349855,-0.14447423395217424,1.552314809182681,0.8772224665898438,-0.023598660010764588,1.418723201036815,-0.18558195150973228,2.294602822374333,0.7976328933322394,-0.2902048261296045,3.423218677949434,2.3783860185520687,-0.6440760551569396,0.6332798897464621,0.3002963271667747,0.6998715023470454,1.3776655599934584,0.42631322556594947,0.17010849742073567,-0.18558195150973228,-0.4633615537366067,0.3548007225100377,3.1414718652717917,-0.2902048261296045,0.8614378522891492,0.15115574181980668,0.372801821409757,0.07442888489169129,-0.0634896107921604,0.5825675708995396,0.28195892039051096,-1.7433267771566325,-1.2644156881924795,-2.380945171359518,-0.5302135415922944,-0.7139106589140215,-0.8815009988157699,0.6998715023470454,0.6164499083295459,-1.5683244293101335,-0.9554014328962437,-0.12407556372432456,1.8899028413533456,-0.14447423395217424,2.4398849348313916,0.3367165517731276,-0.18558195150973228,0.5311795854762361,-0.14447423395217424,0.565514082039327,1.0315318217278158,0.6500364914113959,2.786761095827931,0.7815125855528189,-1.2113555724853857,0.42631322556594947,0.2077445134366247,0.2635357357357556,0.07442888489169129
| 3,376
|
golgi
| 30
| 65
| 2.700654
| 0.00692
|
O15126,O14735,O15127,Q8NBN3,O75787,Q8N6T3,Q96K37,P40616,P61026,O14579,P53365,Q8IZA0,Q9Y371,Q9Y487,Q15904,O14976,Q9Y5P4,Q15836,Q9NTJ5,Q5VW38,Q9UBF8,Q8IXU6,Q9H0U4,Q13190,Q15436,P49755,Q9NR31,Q9H2M9,Q96A49,Q9Y3E0
|
Localization
|
OpenCell Localization
|
opencell_localization
|
505,626,885,12,770,931,667,544,797,657,796,164,685,423,295,676,825,436,572,65,469,207,599,474,486,485,625,365,902,517
|
657,626,1699,676,505,885,914,1622,770,1514,2050,1876,2966,1030,1581,1750,1191,1411,544,485,796,1225,2320,2057,1070,1711,797,2925,1229,2100,2152,1841,474,993,486,3072,436,295,65,1847,2332,207,164,931,12,1313,1354,902,667,1820,599,365,1537,625,572,2435,2076,469,2826,685,517,1056,423,825,1026
|
0.5825675708995396,0.6164499083295459,-0.12407556372432456,0.565514082039327,0.7815125855528189,0.3548007225100377,0.3367165517731276,-0.0835841298387108,0.4615839958458578,-0.023598660010764588,-0.2902048261296045,-0.20629282062173515,-0.8571497916635558,0.2450260771368476,-0.0634896107921604,-0.14447423395217424,0.15115574181980668,0.03550516234149863,0.7327378977030797,0.8296696426224738,0.4439885391534624,0.1321121623528798,-0.41938548886236693,-0.2902048261296045,0.2264292404709339,-0.12407556372432456,0.4439885391534624,-0.808862463451572,0.1321121623528798,-0.31145474882693824,-0.33281539857511017,-0.18558195150973228,0.8455870712937495,0.28195892039051096,0.8296696426224738,-0.980321919952045,0.9241840457318883,1.251645809202598,2.703402284279324,-0.18558195150973228,-0.41938548886236693,1.5784489587449075,1.8539458215110518,0.3367165517731276,3.4381474194828905,0.09374950248621658,0.07442888489169129,0.3548007225100377,0.5825675708995396,-0.16497606147263494,0.6667202646970376,1.0766114520886294,-0.023598660010764588,0.6332798897464621,0.6998715023470454,-0.4633615537366067,-0.2902048261296045,0.8614378522891492,-0.7139106589140215,0.565514082039327,0.7815125855528189,0.2450260771368476,0.9551695312607196,0.42631322556594947,0.2635357357357556
| 3,376
|
Azurophil granule membrane
| 10
| 22
| 2.692955
| 0.007082
|
Q07065,P27105,P42785,O15260,P11279,Q9NQX7,Q92542,P07602,P10253,Q9NZJ7
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
321,163,101,39,356,105,400,333,182,444
|
39,646,1116,2400,1874,333,182,356,163,1192,101,2147,988,321,1812,464,400,1726,3301,105,444,2435
|
3.016205187599177,0.5995459898347874,0.18897117543040606,-0.4633615537366067,-0.20629282062173515,1.135880610204166,1.7685881177452407,1.0915175946894244,1.8539458215110518,0.15115574181980668,2.4092761099767857,-0.33281539857511017,0.28195892039051096,1.179718982402758,-0.16497606147263494,0.8614378522891492,0.9859014847349855,-0.12407556372432456,-1.7136796782151344,2.3783860185520687,0.9085950944992713,-0.4633615537366067
| 3,376
|
Nadh dehydrogenase complex assembly
| 9
| 30
| 2.692298
| 0.007096
|
Q9H061,Q86Y39,Q96CU9,O96000,O95168,Q15070,Q9P0J0,P03886,O43676
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
10,187,78,272,278,243,283,24,26
|
2716,26,1028,2049,367,1670,278,2443,272,24,2947,1015,2019,243,2412,1895,781,187,2160,2112,78,2938,10,1462,1249,3012,283,3258,1613,721
|
-0.6440760551569396,3.1659423425394335,0.2450260771368476,-0.2902048261296045,1.0616453881949772,-0.10377915671823269,1.322192093055503,-0.4855260677859258,1.3361396976874031,3.214321038100156,-0.8329374006846979,0.2635357357357556,-0.26906464190792506,1.445839319599628,-0.4633615537366067,-0.20629282062173515,0.4615839958458578,1.7438162203898662,-0.33281539857511017,-0.31145474882693824,2.5888606637088407,-0.808862463451572,3.460405813603222,0.015900464346774338,0.1321121623528798,-0.8815009988157699,1.322192093055503,-1.3999582054993458,-0.0634896107921604,0.5311795854762361
| 3,376
|
Exocytic vesicle
| 16
| 44
| 2.692112
| 0.0071
|
P0DP25,O15126,Q9GZY8,O43752,O60499,Q9BVK6,P61421,P11279,P20337,P05067,Q92542,O43760,Q7L0J3,P50897,Q9BT78,Q96A57
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
448,505,327,200,41,332,456,356,492,143,400,114,281,22,349,347
|
826,3133,505,1329,200,114,2359,41,507,143,1876,2966,448,356,829,492,2403,2449,2092,22,2318,2523,2611,1484,797,456,1159,1039,3041,3163,1585,2330,2900,1590,281,871,400,851,347,349,332,327,982,939
|
0.4085574264207841,-1.1071432230243936,0.7815125855528189,0.07442888489169129,1.630152502007486,2.2411669014570372,-0.44131505481374056,3.007676347681497,0.7815125855528189,2.018667073067943,-0.20629282062173515,-0.8571497916635558,0.8929413902574874,1.0915175946894244,0.4085574264207841,0.8136850803085195,-0.4633615537366067,-0.4855260677859258,-0.31145474882693824,3.2302833584863713,-0.41938548886236693,-0.5302135415922944,-0.5753864237832664,-0.0038005361770060086,0.4439885391534624,0.8772224665898438,0.17010849742073567,0.2450260771368476,-0.9306254080954044,-1.1589358324480967,-0.0634896107921604,-0.41938548886236693,-0.784923636467135,-0.0634896107921604,1.322192093055503,0.372801821409757,0.9859014847349855,0.3907205059965324,1.1211517662256676,1.1211517662256676,1.1505511630774563,1.1651638225306005,0.3002963271667747,0.3367165517731276
| 3,376
|
Ceramide biosynthetic process
| 6
| 12
| 2.688432
| 0.007179
|
Q16739,Q9NRA0,Q96G23,P04062,Q13510,O15121
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
64,489,167,90,111,123
|
123,491,1868,90,1303,111,64,744,167,489,2120,1173
|
2.1428207883227306,0.8136850803085195,-0.20629282062173515,2.4902865084460193,0.09374950248621658,2.315743939212719,2.7127698952516086,0.4965378185069035,1.8418778252097934,0.8296696426224738,-0.31145474882693824,0.17010849742073567
| 3,376
|
Abc transporter disorders
| 12
| 44
| 2.684809
| 0.007257
|
P61289,P49721,P25787,Q9UBV2,Q9BUN8,P28070,Q9UL46,Q14997,P20618,P28072,P49720,Q92530
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
450,99,263,296,430,138,503,211,239,179,244,384
|
701,2440,2808,1285,1326,2301,1330,1217,1090,1794,1628,239,543,263,2090,2720,1880,138,179,687,2721,1296,1032,244,99,1481,2788,2148,810,450,1714,1523,1636,1382,1759,211,1941,384,1134,2168,430,296,503,1545
|
0.5311795854762361,-0.4855260677859258,-0.7139106589140215,0.09374950248621658,0.07442888489169129,-0.41938548886236693,0.07442888489169129,0.1321121623528798,0.2077445134366247,-0.16497606147263494,-0.0835841298387108,1.445839319599628,0.7327378977030797,1.3776655599934584,-0.31145474882693824,-0.6440760551569396,-0.20629282062173515,2.0415749265642926,1.7809092990421234,0.5483849475613088,-0.6440760551569396,0.09374950248621658,0.2450260771368476,1.4323066040977575,2.4195100841990267,-0.0038005361770060086,-0.6905032048336213,-0.33281539857511017,0.42631322556594947,0.8929413902574874,-0.12407556372432456,-0.023598660010764588,-0.0835841298387108,0.055014368762545285,-0.14447423395217424,1.552314809182681,-0.22710959688583782,1.0315318217278158,0.18897117543040606,-0.33281539857511017,0.9397087056445106,1.251645809202598,0.7976328933322394,-0.023598660010764588
| 3,376
|
Elevated pulmonary artery pressure
| 7
| 23
| 2.682953
| 0.007298
|
Q8IZA0,Q14108,P04062,P00403,O96000,P03886,O75844
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
164,37,90,267,272,24,88
|
1326,2220,88,272,267,2306,24,90,3135,793,3097,2228,1884,311,1015,2494,37,1561,780,164,1906,2006,2392
|
0.07442888489169129,-0.37587289727828466,2.5201665300557425,1.3361396976874031,1.3500342456184196,-0.41938548886236693,3.214321038100156,2.4902865084460193,-1.1071432230243936,0.4439885391534624,-1.0306021517672246,-0.37587289727828466,-0.20629282062173515,1.208658359818944,0.2635357357357556,-0.5078096934092219,3.050094664845848,-0.043494737915892735,0.4615839958458578,1.8539458215110518,-0.20629282062173515,-0.2480332200865538,-0.44131505481374056
| 3,376
|
Abnormal circulating cholesterol concentration
| 12
| 30
| 2.680322
| 0.007355
|
P50402,Q15904,Q8N511,Q14739,O75431,Q13045,Q15800,P07602,Q9UJS0,Q9NZJ7,Q9H9E3,Q15392
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
417,295,40,428,392,399,116,333,642,444,250,191
|
392,2306,1440,333,843,2922,1412,1675,417,2490,1227,812,2152,1199,399,1162,428,191,1203,116,295,40,1389,2290,1171,250,640,444,2546,642
|
1.0011735038559333,-0.41938548886236693,0.015900464346774338,1.135880610204166,0.3907205059965324,-0.808862463451572,0.03550516234149863,-0.10377915671823269,0.9551695312607196,-0.5078096934092219,0.1321121623528798,0.42631322556594947,-0.33281539857511017,0.15115574181980668,0.9859014847349855,0.17010849742073567,0.9397087056445106,1.6937468932790258,0.15115574181980668,2.208698172161687,1.251645809202598,3.016205187599177,0.055014368762545285,-0.3975717877794668,0.17010849742073567,1.418723201036815,0.6164499083295459,0.9085950944992713,-0.5302135415922944,0.6164499083295459
| 3,376
|
Calcium signaling pathway
| 9
| 18
| 2.677819
| 0.00741
|
P0DP25,Q9NRA0,Q9Y277,P21796,P45880,P46020,P16615,P12236,P12235
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
448,489,231,8,11,434,302,497,154
|
1118,448,154,497,302,2447,1829,3117,829,8,11,434,1198,845,528,489,1212,231
|
0.18897117543040606,0.8929413902574874,1.9607270744213334,0.7976328933322394,1.2230433462408152,-0.4855260677859258,-0.18558195150973228,-1.0559648852353496,0.4085574264207841,3.555036482266552,3.4381474194828905,0.9241840457318883,0.15115574181980668,0.3907205059965324,0.7490655969974919,0.8296696426224738,0.15115574181980668,1.486136587048457
| 3,376
|
Calcium ion binding
| 35
| 81
| 2.661868
| 0.007771
|
O43681,Q6NUK1,P80303,Q9BPX6,P42566,P07384,P04083,O75746,P60660,P61201,Q96AY3,Q02487,P41208,Q9UM22,P16615,P12814,P50995,Q14257,P0DP25,Q8WVQ1,Q6KCM7,Q8NF37,Q9NWM8,P27824,Q96A33,O43852,P12429,P55327,Q9Y4G8,Q02818,O95202,Q9UJS0,Q9H4M9,P60903,Q9BRK5
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
506,780,4,654,755,394,393,769,774,775,549,661,168,43,302,808,689,189,448,452,212,464,351,727,346,472,606,620,373,242,238,642,639,757,255
|
1661,1919,506,1216,472,2303,769,1578,238,393,2786,394,1405,1476,448,606,808,1407,3068,2916,2308,302,3268,3031,3117,917,3033,727,2680,1445,865,2921,168,755,1799,1885,689,620,774,757,775,2862,4,661,242,2059,1198,1938,1643,2190,189,2154,1267,1100,212,780,1950,1848,1897,834,464,452,346,549,1596,1534,1726,654,255,1728,1245,639,351,3028,2779,1212,1657,642,43,1734,373
|
-0.10377915671823269,-0.22710959688583782,0.7815125855528189,0.1321121623528798,0.8455870712937495,-0.41938548886236693,0.4615839958458578,-0.0634896107921604,1.445839319599628,1.0011735038559333,-0.6905032048336213,1.0011735038559333,0.03550516234149863,-0.0038005361770060086,0.8929413902574874,0.6500364914113959,0.42631322556594947,0.03550516234149863,-0.980321919952045,-0.808862463451572,-0.41938548886236693,1.2230433462408152,-1.4833391917688719,-0.9306254080954044,-1.0559648852353496,0.3367165517731276,-0.9306254080954044,0.5138974074088837,-0.6210539026805592,0.015900464346774338,0.372801821409757,-0.808862463451572,1.829768258961035,0.47910021734806124,-0.16497606147263494,-0.20629282062173515,0.5483849475613088,0.6332798897464621,0.4615839958458578,0.47910021734806124,0.4615839958458578,-0.7611195948253038,3.8158495588954837,0.5825675708995396,1.445839319599628,-0.2902048261296045,0.15115574181980668,-0.22710959688583782,-0.0835841298387108,-0.354287776657499,1.706330585324128,-0.33281539857511017,0.11297700392516687,0.2077445134366247,1.552314809182681,0.4615839958458578,-0.22710959688583782,-0.18558195150973228,-0.20629282062173515,0.4085574264207841,0.8614378522891492,0.8929413902574874,1.1211517662256676,0.7327378977030797,-0.0634896107921604,-0.023598660010764588,-0.12407556372432456,0.5995459898347874,1.4050887812930244,-0.12407556372432456,0.1321121623528798,0.6164499083295459,1.1211517662256676,-0.9059924038468624,-0.6672254158451334,0.15115574181980668,-0.0835841298387108,0.6164499083295459,2.990550171469064,-0.12407556372432456,1.0616453881949772
| 3,376
|
Abnormal biliary tract morphology
| 11
| 25
| 2.660439
| 0.007804
|
O43681,Q10713,Q14108,O43933,Q14739,P09601,Q9UJW0,P50542,P07602,Q9NZJ7,P04062
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
506,608,37,539,428,15,502,382,333,444,90
|
506,539,2306,90,333,15,677,2404,2230,1376,382,1756,1069,608,1302,37,428,849,2507,980,1211,444,502,1613,840
|
0.7815125855528189,0.7327378977030797,-0.41938548886236693,2.4902865084460193,1.135880610204166,3.3779946752279097,0.565514082039327,-0.4633615537366067,-0.37587289727828466,0.055014368762545285,1.0315318217278158,-0.14447423395217424,0.2264292404709339,0.6500364914113959,0.09374950248621658,3.050094664845848,0.9397087056445106,0.3907205059965324,-0.5078096934092219,0.3002963271667747,0.15115574181980668,0.9085950944992713,0.7976328933322394,-0.0634896107921604,0.4085574264207841
| 3,376
|
Aminoglycan metabolic process
| 7
| 18
| 2.658661
| 0.007845
|
P04066,P15586,P06865,Q8NCH0,P54802,P16278,Q7LGA3
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
291,319,262,44,121,93,95
|
538,3064,2754,291,262,1185,381,319,93,1094,121,2100,95,44,1565,1001,823,1657
|
0.7327378977030797,-0.980321919952045,-0.6672254158451334,1.2941363054249848,1.3776655599934584,0.15115574181980668,1.0315318217278158,1.179718982402758,2.470216891564265,0.2077445134366247,2.1649209674192837,-0.31145474882693824,2.4398849348313916,2.973331959590957,-0.043494737915892735,0.28195892039051096,0.42631322556594947,-0.0835841298387108
| 3,376
|
Organic hydroxy compound biosynthetic process
| 15
| 55
| 2.658575
| 0.007847
|
Q9NRA0,P04035,P16435,Q14739,Q16850,Q14534,P00374,Q9Y4G8,Q13510,Q9UKG1,Q9H2C2,Q15800,P04062,O14734,Q15392
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
489,261,266,428,141,235,110,373,111,371,53,116,90,439,191
|
2256,2130,439,3133,491,1868,1217,1794,110,1404,261,90,1580,1290,1292,965,266,2484,1094,1750,1254,2015,1632,2451,843,2644,920,1802,2948,946,2927,1303,111,2866,235,428,2284,191,1203,116,759,141,2205,1853,1020,2803,3125,53,2343,489,2546,2780,371,373,2850
|
-0.3975717877794668,-0.33281539857511017,0.9085950944992713,-1.1071432230243936,0.8136850803085195,-0.20629282062173515,0.1321121623528798,-0.16497606147263494,2.315743939212719,0.03550516234149863,1.3776655599934584,2.4902865084460193,-0.0634896107921604,0.09374950248621658,0.09374950248621658,0.3002963271667747,1.3638760848112592,-0.5078096934092219,0.2077445134366247,-0.14447423395217424,0.11297700392516687,-0.26906464190792506,-0.0835841298387108,-0.4855260677859258,0.3907205059965324,-0.5981577547393172,0.3367165517731276,-0.16497606147263494,-0.8329374006846979,0.3185486441921405,-0.808862463451572,0.09374950248621658,2.315743939212719,-0.7611195948253038,1.4593216736559882,0.9397087056445106,-0.3975717877794668,1.6937468932790258,0.15115574181980668,2.208698172161687,0.47910021734806124,2.030139933980146,-0.354287776657499,-0.18558195150973228,0.2635357357357556,-0.6905032048336213,-1.0559648852353496,2.8591098246251514,-0.41938548886236693,0.8296696426224738,-0.5302135415922944,-0.6672254158451334,1.0616453881949772,1.0616453881949772,-0.7374490318787568
| 3,376
|
Alcohol biosynthetic process
| 11
| 38
| 2.658192
| 0.007856
|
Q9NRA0,P04035,P16435,Q14739,Q16850,P00374,Q13510,Q9H2C2,Q15800,P04062,Q15392
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
489,261,266,428,141,110,111,53,116,90,191
|
2256,491,1868,1217,1794,110,1404,261,90,1290,1292,965,266,2484,1094,2451,843,2644,920,1802,2948,946,2927,1303,111,2866,428,2284,191,1203,116,759,141,2803,53,2343,489,2546
|
-0.3975717877794668,0.8136850803085195,-0.20629282062173515,0.1321121623528798,-0.16497606147263494,2.315743939212719,0.03550516234149863,1.3776655599934584,2.4902865084460193,0.09374950248621658,0.09374950248621658,0.3002963271667747,1.3638760848112592,-0.5078096934092219,0.2077445134366247,-0.4855260677859258,0.3907205059965324,-0.5981577547393172,0.3367165517731276,-0.16497606147263494,-0.8329374006846979,0.3185486441921405,-0.808862463451572,0.09374950248621658,2.315743939212719,-0.7611195948253038,0.9397087056445106,-0.3975717877794668,1.6937468932790258,0.15115574181980668,2.208698172161687,0.47910021734806124,2.030139933980146,-0.6905032048336213,2.8591098246251514,-0.41938548886236693,0.8296696426224738,-0.5302135415922944
| 3,376
|
Vascular transport
| 6
| 13
| 2.655299
| 0.007924
|
P11166,P53985,P02786,P55011,P30825,P08183
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
408,199,407,411,56,216
|
1699,1062,407,216,408,56,2722,199,411,1384,2196,443,1658
|
-0.12407556372432456,0.2264292404709339,0.9705669749994547,1.5391760995751391,0.9705669749994547,2.7958932046881895,-0.6440760551569396,1.6429624336734927,0.9705669749994547,0.055014368762545285,-0.354287776657499,0.9085950944992713,-0.0835841298387108
| 3,376
|
Defective cftr causes cystic fibrosis
| 12
| 43
| 2.654506
| 0.007942
|
P61289,P49721,P25787,Q9UBV2,Q9BUN8,P28070,Q9UL46,Q14997,P20618,P28072,P49720,Q92530
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
450,99,263,296,430,138,503,211,239,179,244,384
|
701,2440,2808,1285,2301,1330,1217,1090,1794,1628,239,543,263,2090,2720,1880,138,179,687,2721,1296,1032,244,99,1481,2788,2148,810,450,1714,1523,1636,1382,1759,211,1941,384,1134,2168,430,296,503,1545
|
0.5311795854762361,-0.4855260677859258,-0.7139106589140215,0.09374950248621658,-0.41938548886236693,0.07442888489169129,0.1321121623528798,0.2077445134366247,-0.16497606147263494,-0.0835841298387108,1.445839319599628,0.7327378977030797,1.3776655599934584,-0.31145474882693824,-0.6440760551569396,-0.20629282062173515,2.0415749265642926,1.7809092990421234,0.5483849475613088,-0.6440760551569396,0.09374950248621658,0.2450260771368476,1.4323066040977575,2.4195100841990267,-0.0038005361770060086,-0.6905032048336213,-0.33281539857511017,0.42631322556594947,0.8929413902574874,-0.12407556372432456,-0.023598660010764588,-0.0835841298387108,0.055014368762545285,-0.14447423395217424,1.552314809182681,-0.22710959688583782,1.0315318217278158,0.18897117543040606,-0.33281539857511017,0.9397087056445106,1.251645809202598,0.7976328933322394,-0.023598660010764588
| 3,376
|
Macromolecule transmembrane transporter activity
| 7
| 12
| 2.650829
| 0.008029
|
O60830,Q9NS69,Q99595,P49755,Q15388,Q07820,O14925
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
0,2,3,485,206,435,190
|
190,0,2305,557,485,1482,2568,435,206,3,2,719
|
1.6937468932790258,4.625302186087037,-0.41938548886236693,0.7163400404236764,0.8296696426224738,-0.0038005361770060086,-0.552738738110152,0.9241840457318883,1.5784489587449075,4.079811310189964,4.3051831514783245,0.5311795854762361
| 3,376
|
Pigment metabolic process
| 8
| 28
| 2.650765
| 0.008031
|
P22830,O75027,P30519,P49915,P09601,Q9Y4G8,P00813,O00264
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
128,289,33,35,15,373,49,277
|
277,3133,289,1549,49,2558,1091,1701,15,1927,2562,128,1632,33,2268,3146,2642,1223,35,866,2274,971,1386,1732,672,3095,371,373
|
1.322192093055503,-1.1071432230243936,1.2941363054249848,-0.043494737915892735,2.9211164682126753,-0.552738738110152,0.2077445134366247,-0.12407556372432456,3.3779946752279097,-0.22710959688583782,-0.552738738110152,2.098189349032581,-0.0835841298387108,3.083627658114699,-0.3975717877794668,-1.132961948971579,-0.5981577547393172,0.1321121623528798,3.05851107937242,0.372801821409757,-0.3975717877794668,0.3002963271667747,0.055014368762545285,-0.12407556372432456,0.5825675708995396,-1.0053883317133208,1.0616453881949772,1.0616453881949772
| 3,376
|
Amyloid precursor protein catabolic process
| 7
| 16
| 2.650227
| 0.008044
|
Q13464,Q9NQC3,P49840,Q92542,O75298,O95197,Q15392
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
322,106,364,400,366,30,191
|
1400,366,30,2092,2489,485,364,322,3041,1525,191,2105,400,1424,1207,106
|
0.03550516234149863,1.0616453881949772,3.108547336875158,-0.31145474882693824,-0.5078096934092219,0.8296696426224738,1.0766114520886294,1.179718982402758,-0.9306254080954044,-0.023598660010764588,1.6937468932790258,-0.31145474882693824,0.9859014847349855,0.03550516234149863,0.15115574181980668,2.357634147809756
| 3,376
|
Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen
| 8
| 32
| 2.643996
| 0.008193
|
P30519,Q14534,Q16850,O15121,P09601,Q6UW02,Q15800,Q9NVH6
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
33,235,141,123,15,176,116,251
|
1436,1370,123,807,2441,1741,2603,1972,15,1120,266,33,946,2768,1938,235,116,141,1453,2331,1307,176,2029,530,782,414,760,3179,1279,251,3028,3079
|
0.015900464346774338,0.055014368762545285,2.1428207883227306,0.42631322556594947,-0.4855260677859258,-0.14447423395217424,-0.5753864237832664,-0.2480332200865538,3.3779946752279097,0.18897117543040606,1.3638760848112592,3.083627658114699,0.3185486441921405,-0.6672254158451334,-0.22710959688583782,1.4593216736559882,2.208698172161687,2.030139933980146,0.015900464346774338,-0.41938548886236693,0.09374950248621658,1.7931876481313542,-0.26906464190792506,0.7490655969974919,0.4615839958458578,0.9705669749994547,0.47910021734806124,-1.185066492546918,0.11297700392516687,1.418723201036815,-0.9059924038468624,-0.980321919952045
| 3,376
|
Golgi cisterna
| 10
| 26
| 2.64166
| 0.00825
|
Q8NBZ7,Q15363,Q9BXS4,O95249,Q8NBN3,O00461,P04439,Q9H4A6,Q10472,Q9Y3A3
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
224,5,397,201,12,80,273,213,285,385
|
80,2180,201,273,1187,1154,1262,2864,1841,1199,285,608,2900,5,12,224,1313,452,1498,1001,668,397,856,213,3344,385
|
2.5693783360444082,-0.354287776657499,1.630152502007486,1.3361396976874031,0.15115574181980668,0.17010849742073567,0.11297700392516687,-0.7611195948253038,-0.18558195150973228,0.15115574181980668,1.3081910804853814,0.6500364914113959,-0.784923636467135,3.708771690562757,3.4381474194828905,1.5127538943193948,0.09374950248621658,0.8929413902574874,-0.0038005361770060086,0.28195892039051096,0.5825675708995396,1.0011735038559333,0.3907205059965324,1.552314809182681,-2.380945171359518,1.0315318217278158
| 3,376
|
Progressive visual loss
| 8
| 22
| 2.640278
| 0.008284
|
P00846,O75503,O00170,O60313,O75306,P50897,P03886,O14773
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
7,137,482,329,367,22,24,25
|
482,826,25,329,367,137,723,7,24,2638,2011,3116,1976,1706,22,2274,1488,2498,1202,1526,583,1421
|
0.8296696426224738,0.4085574264207841,3.190224570239214,1.1505511630774563,1.0616453881949772,2.0415749265642926,0.5138974074088837,3.576464581247993,3.214321038100156,-0.5981577547393172,-0.26906464190792506,-1.0559648852353496,-0.2480332200865538,-0.12407556372432456,3.2302833584863713,-0.3975717877794668,-0.0038005361770060086,-0.5078096934092219,0.15115574181980668,-0.023598660010764588,0.6833317551050844,0.03550516234149863
| 3,376
|
Nucleotide transport
| 8
| 15
| 2.639482
| 0.008303
|
Q9H2D1,Q8TB61,Q86VD7,Q6KCM7,Q9HC21,P12236,P12235,Q9BSK2
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
42,109,177,212,438,497,154,28
|
1062,2009,1118,154,497,2722,621,212,780,177,109,1044,28,42,438
|
0.2264292404709339,-0.26906464190792506,0.18897117543040606,1.9607270744213334,0.7976328933322394,-0.6440760551569396,0.6332798897464621,1.552314809182681,0.4615839958458578,1.7931876481313542,2.3262652314834207,0.2450260771368476,3.1496497632836333,2.990550171469064,0.9241840457318883
| 3,376
|
Membrane microdomain
| 14
| 68
| 2.636193
| 0.008384
|
P35613,P11166,Q8WTV0,P27105,P10644,P30154,P46108,P21796,P05067,P09601,P50897,O14773,O15118,O75955
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
256,408,130,163,317,198,358,8,143,15,22,25,157,343
|
1866,446,1699,25,157,343,1794,2222,2181,1373,628,1671,143,1118,1796,2559,2786,792,1443,15,317,408,1747,1878,2447,1829,3268,3031,2448,829,2403,8,2228,163,1222,1974,198,2488,1976,2607,256,1479,2722,2489,358,1299,2610,22,757,2764,1340,991,3253,3104,1038,2530,1161,1525,1760,1812,871,130,2803,854,1431,2713,1283,1179
|
-0.20629282062173515,0.8929413902574874,-0.12407556372432456,3.190224570239214,1.9136707952245202,1.1211517662256676,-0.16497606147263494,-0.37587289727828466,-0.354287776657499,0.055014368762545285,0.6164499083295459,-0.10377915671823269,2.018667073067943,0.18897117543040606,-0.16497606147263494,-0.552738738110152,-0.6905032048336213,0.4439885391534624,0.015900464346774338,3.3779946752279097,1.179718982402758,0.9705669749994547,-0.14447423395217424,-0.20629282062173515,-0.4855260677859258,-0.18558195150973228,-1.4833391917688719,-0.9306254080954044,-0.4855260677859258,0.4085574264207841,-0.4633615537366067,3.555036482266552,-0.37587289727828466,1.8539458215110518,0.1321121623528798,-0.2480332200865538,1.6429624336734927,-0.5078096934092219,-0.2480332200865538,-0.5753864237832664,1.3914030126962775,-0.0038005361770060086,-0.6440760551569396,-0.5078096934092219,1.0915175946894244,0.09374950248621658,-0.5753864237832664,3.2302833584863713,0.47910021734806124,-0.6672254158451334,0.07442888489169129,0.28195892039051096,-1.3999582054993458,-1.0306021517672246,0.2450260771368476,-0.5302135415922944,0.17010849742073567,-0.023598660010764588,-0.14447423395217424,-0.16497606147263494,0.372801821409757,2.0869404990527856,-0.6905032048336213,0.3907205059965324,0.03550516234149863,-0.6210539026805592,0.11297700392516687,0.17010849742073567
| 3,376
|
Subsets and Splits
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