term
stringlengths 2
121
| overlap
int64 6
281
| setsize
int64 7
499
| score
float64 1.96
10.6
| pval
float64 0
0.05
| edge
stringlengths 41
1.97k
| type
stringclasses 5
values | subtype
stringclasses 24
values | subtype_key
stringclasses 24
values | edge_idxs
stringlengths 11
1.17k
| ann_idxs
stringlengths 19
2.31k
| ann_vals
stringlengths 124
9.94k
| sig_size
int64 2.2k
3.73k
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Ion transmembrane transport
| 71
| 167
| 3.098232
| 0.001947
|
Q9BPX6,P51798,Q8N4V1,P30825,Q9C0H2,Q9Y277,Q9HD26,P11413,Q9H2D1,Q9Y619,P78417,Q8IYU8,Q9NRA0,Q6P4A7,P61421,P24539,P00846,O60831,Q4KMQ2,P07384,Q9UDW1,Q9HD20,P53007,P21796,Q9HC07,P45880,Q9NVV0,Q9UJS0,P46934,P16615,Q7KZN9,Q9UBX3,P98194,Q13423,Q9UHG3,P20674,Q9HC21,O75844,Q86VD7,Q6KCM7,P56385,Q96GC9,P05067,P05023,Q9Y6M7,P56134,Q02978,O43865,Q8WWC4,Q15526,O75027,P00403,P12236,P12235,Q9BQT8,P05141,P13073,Q6P4Q7,O95202,O95563,Q8TDW0,Q9NW15,O75746,P27105,Q15041,Q8TB61,O75964,Q6PML9,Q8N668,Q70HW3,P35670
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
512,640,1,130,135,136,526,393,15,272,402,533,407,152,655,408,28,413,540,548,36,165,425,41,43,44,170,437,557,178,572,59,568,189,63,317,193,71,72,76,582,78,204,707,726,721,594,342,733,731,473,95,375,97,475,609,100,354,358,499,618,234,489,490,508,112,124,364,249,248,632
|
1423,2058,1559,1243,2513,1189,1450,816,727,342,2377,413,473,2648,1812,1905,489,71,1141,1397,124,358,499,784,95,28,707,993,204,609,946,751,2965,548,2207,765,2002,907,818,1785,1909,393,97,375,100,178,1910,2005,3139,845,317,2404,3051,3209,41,408,3023,490,2240,2653,2930,2129,130,1209,632,2684,981,1498,2041,3078,1704,44,557,1880,2408,3271,965,640,425,1817,1433,2131,1196,721,582,655,1437,1379,402,568,869,1438,594,1404,2573,3317,1590,189,1146,1820,871,1361,508,2837,731,1478,2478,540,76,152,354,364,1249,248,572,72,2635,533,1,249,1001,112,618,733,1576,78,1686,1024,2942,892,2794,512,475,1318,2696,135,2580,3375,15,1895,1803,1171,1346,43,193,165,526,407,1204,170,234,59,36,1188,63,1350,437,2233,1690,136,1257,2236,1658,1296,272,3037,726
|
0.007339737540638098,-0.3339900772103585,-0.07988664715431047,0.12174807413919582,-0.599121814464143,0.1641085471368729,-0.007112210270966405,0.5062366837929436,0.6118374126406803,1.245907190269227,-0.5042236629761834,1.102408190994822,0.9802563479044419,-0.6793500706356256,-0.21309725685462735,-0.2581525139593801,0.9431396034941706,2.457521700066298,0.20617963072146406,0.021757766555510514,2.075393782526737,1.222218044879942,0.9182717672838793,0.5460481617509392,2.2693262981715874,3.0624281306689123,0.6379588946017836,0.31698540656083257,1.6798031111121596,0.7669425203474032,0.35802993391519033,0.5856054418382873,-0.9097982049966251,0.8430670510338878,-0.41078076891872717,0.5724477159799228,-0.3035420687482125,0.39880353572925303,0.5062366837929436,-0.19815223757022424,-0.2581525139593801,1.1506078804869229,2.2592655177971985,1.1865154018947937,2.2390960928105765,1.7674589112604508,-0.2581525139593801,-0.3035420687482125,-1.1493665932391064,0.46616755845459307,1.30474106378976,-0.5199376859291878,-1.0113097535490851,-1.2906578721061541,2.8548455407684523,1.1144929997983144,-0.9772829358324227,0.9431396034941706,-0.42625550585234623,-0.6793500706356256,-0.8763358915188677,-0.364590575074656,2.023358667895234,0.1500207496396212,0.7285278893546684,-0.6955235731118161,0.3306972515746962,-0.03611853455253771,-0.31874711143957013,-1.0455292059601446,-0.1535347647507937,2.7903132643602064,0.8304441394676204,-0.24309720612430855,-0.5199376859291878,-1.4720700709953676,0.3443787137519083,0.7156700563298527,1.0660128924007646,-0.21309725685462735,0.007339737540638098,-0.364590575074656,0.1641085471368729,0.6249119037114952,0.8051212350176506,0.6898742644114918,0.007339737540638098,0.03614204326984603,1.1385927506711437,0.8177955706609692,0.4393099348893643,0.007339737540638098,0.7924210222267182,0.021757766555510514,-0.631086208801837,-1.7356350214699037,-0.09454567529886222,1.7347305225090166,0.20617963072146406,-0.21309725685462735,0.4393099348893643,0.050492732938221645,0.9058005368829619,-0.7934797786581159,0.6118374126406803,-0.021598244629604746,-0.5673244671099098,0.8556644142476869,2.428173597886573,1.9073546394248442,1.2340738196350072,1.21033977687557,0.12174807413919582,1.5347102368011099,0.8177955706609692,2.457521700066298,-0.6632195009402341,0.8682363372946176,3.918017746429074,1.5347102368011099,0.31698540656083257,2.1679949059006707,0.7541640070071953,0.6118374126406803,-0.07988664715431047,2.428173597886573,-0.13873418933689516,0.3032430368863615,-0.8763358915188677,0.42583726441943925,-0.760651747905037,0.9058005368829619,0.9802563479044419,0.07909400602166337,-0.6955235731118161,1.991931331193204,-0.631086208801837,-8.716957634029924,3.349044243996922,-0.24309720612430855,-0.19815223757022424,0.19218783473832943,0.06480999958601061,2.8088173906325995,1.72378323442192,1.8431719091236531,0.8807829276640542,1.126554488303031,0.1641085471368729,1.8216320518149403,1.5909114869453034,2.6498026320516255,2.9187354965517494,0.17816419100440917,2.62132664953133,0.06480999958601061,1.0538338490539432,-0.41078076891872717,-0.13873418933689516,1.991931331193204,0.12174807413919582,-0.41078076891872717,-0.12396926881478841,0.09334491384878002,1.4551752366331643,-0.9772829358324227,0.6249119037114952
| 3,376
|
Protein insertion into er membrane
| 7
| 15
| 3.089545
| 0.002005
|
Q8N4V1,Q7L5D6,O43681,Q9NPA0,Q96A33,Q15629,P46379
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
1,296,137,397,243,85,409
|
2124,137,1098,409,431,1437,2601,85,1133,296,1,1200,243,397,903
|
-0.364590575074656,1.9814208160018005,0.23406828346498643,1.1144929997983144,1.0538338490539432,0.007339737540638098,-0.647131625751063,2.3789579376592007,0.22013973023415834,1.3630278999226435,3.918017746429074,0.1641085471368729,1.5572509969346298,1.1506078804869229,0.4123351763696069
| 3,376
|
Organelle membrane contact site
| 11
| 17
| 3.080805
| 0.002064
|
Q14849,Q96TC7,Q5XKP0,Q96N66,P27824,P51572,O96008,Q15388,Q9NTJ5,O43865,Q9Y320
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
98,226,585,225,671,673,523,242,472,342,480
|
1393,1323,342,1840,523,671,673,98,242,585,1221,225,808,226,1549,472,480
|
0.021757766555510514,0.06480999958601061,1.245907190269227,-0.22807885031082178,0.8807829276640542,0.6769360722247575,0.6769360722247575,2.249188800352927,1.5572509969346298,0.8051212350176506,0.1500207496396212,1.602091776312444,0.5195356321277029,1.602091776312444,-0.06526256357203314,0.9925796692463879,0.9802563479044419
| 3,376
|
Exopeptidase activity
| 14
| 32
| 3.078321
| 0.002082
|
P42785,P10619,Q9HB40,O75844,Q0VDG4,O75976,Q969V3,Q9UIQ6,Q7Z2K6,Q9H3G5,P55786,Q9NZ08,P09960,O14773
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
378,132,227,71,488,554,177,213,276,576,151,314,252,61
|
61,71,554,1699,252,132,2536,3232,2128,1211,378,1195,151,488,2181,1542,1339,276,999,617,1711,177,2460,742,576,2117,227,1956,2345,1991,314,213
|
2.62132664953133,2.457521700066298,0.8304441394676204,-0.1535347647507937,1.5234094998830219,2.012900196950257,-0.6150830158119736,-1.344508871789742,-0.364590575074656,0.1500207496396212,1.1745691139378525,0.1641085471368729,1.9179887298526617,0.9555364168366788,-0.3953451725415673,-0.06526256357203314,0.06480999958601061,1.4322648574279548,0.31698540656083257,0.7541640070071953,-0.1535347647507937,1.7783307767900958,-0.5514878660885424,0.5987352995655117,0.8177955706609692,-0.34927116493347793,1.602091776312444,-0.27324496497470774,-0.4729166554316845,-0.2883747518392183,1.3164418516370977,1.6576974846458383
| 3,376
|
Ion channel transport
| 15
| 29
| 3.072709
| 0.002121
|
P51798,Q4KMQ2,Q9HD20,Q9C0H2,Q9NW15,Q9Y487,P27105,Q99576,P16615,Q15904,Q93050,P61421,P35670,P98194,Q13555
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
640,540,165,135,234,109,490,207,178,595,55,655,632,568,254
|
707,993,178,845,2404,3051,490,2129,632,1498,2041,640,2131,655,568,2075,1146,254,595,540,55,207,135,1803,165,234,1350,109,1810
|
0.6379588946017836,0.31698540656083257,1.7674589112604508,0.46616755845459307,-0.5199376859291878,-1.0113097535490851,0.9431396034941706,-0.364590575074656,0.7285278893546684,-0.03611853455253771,-0.31874711143957013,0.7156700563298527,-0.364590575074656,0.6898742644114918,0.8177955706609692,-0.3339900772103585,0.20617963072146406,1.5120884232445022,0.7924210222267182,0.8556644142476869,2.6781524570436264,1.6798031111121596,1.991931331193204,-0.19815223757022424,1.8431719091236531,1.5909114869453034,0.06480999958601061,2.2087214952641787,-0.19815223757022424
| 3,376
|
Action tremor
| 23
| 59
| 3.068645
| 0.00215
|
Q9BUB7,O43681,Q14108,P00846,Q9NR77,Q9H6K4,Q99720,O95140,Q96DA6,Q9NZJ7,Q9BYI3,Q6PJG6,O14773,Q5T8D3,Q9UNE7,O75306,P03886,P07602,O75027,Q96RL7,Q9NW15,Q9UBB4,Q5JRX3
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
645,137,147,28,31,160,164,670,563,173,692,571,61,318,319,566,68,469,473,96,234,384,381
|
3284,61,2123,1694,137,473,566,961,991,670,1934,28,68,1158,469,2517,1965,1452,1847,1632,1429,2592,2501,793,3078,2656,2565,753,2411,1564,2271,2573,147,1062,2186,381,318,1709,2717,571,700,2156,2767,563,96,2942,2639,164,645,692,160,1956,31,234,173,384,319,1370,1296
|
-1.5648744215576544,2.62132664953133,-0.364590575074656,-0.1535347647507937,1.9814208160018005,0.9802563479044419,0.8177955706609692,0.3443787137519083,0.31698540656083257,0.6769360722247575,-0.27324496497470774,3.0624281306689123,2.525480253725994,0.19218783473832943,0.9925796692463879,-0.599121814464143,-0.2883747518392183,-0.007112210270966405,-0.22807885031082178,-0.12396926881478841,0.007339737540638098,-0.647131625751063,-0.5832023743822983,0.5328060821965044,-1.0455292059601446,-0.6793500706356256,-0.631086208801837,0.5856054418382873,-0.5199376859291878,-0.07988664715431047,-0.44176959203476396,-0.631086208801837,1.939203453754038,0.2756661511961478,-0.3953451725415673,1.1745691139378525,1.30474106378976,-0.1535347647507937,-0.7117402486747223,0.8177955706609692,0.6509785063189131,-0.37994850970962596,-0.7443040905812541,0.8304441394676204,2.2693262981715874,-0.8763358915188677,-0.6632195009402341,1.8431719091236531,0.7156700563298527,0.6639708590611185,1.8646386144308038,-0.27324496497470774,3.0446410783605184,1.5909114869453034,1.8000185178422223,1.1745691139378525,1.30474106378976,0.050492732938221645,0.09334491384878002
| 3,376
|
Transport of small molecules
| 57
| 155
| 3.067206
| 0.002161
|
Q9BPX6,P51798,Q8N4V1,P63218,P30825,Q10713,Q9C0H2,Q9Y277,P09601,P51665,Q8IYU8,P40855,P61421,Q9UL46,Q9UBV2,Q4KMQ2,Q9BUN8,P61289,Q9HD20,P30519,P49721,P21796,P45880,Q8WTV0,P16615,Q93050,P28072,Q8WWI5,Q9UBX3,P98194,P20618,P05023,Q9Y6M7,Q99576,Q15904,P35611,P35613,O75027,P12235,P28070,P05141,O95202,Q92530,Q8TDW0,Q9NW15,Q9Y487,P27105,Q8TB61,O15118,Q99436,P28074,P35610,P12236,O00487,Q70HW3,P35670,Q13555
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
512,640,1,641,130,388,135,136,9,401,533,149,655,281,289,540,416,674,165,38,166,41,44,300,178,55,430,573,59,568,330,707,726,207,595,720,603,473,97,353,609,358,231,618,234,109,490,112,506,503,624,501,375,505,248,632,254
|
921,3046,2779,505,2780,506,1189,1300,473,1905,1373,1843,3049,2353,3020,358,2678,1699,707,993,609,2170,1302,765,2002,2288,9,1303,819,97,375,1875,178,1910,2005,1877,845,1966,330,2404,3051,3173,41,1669,895,2038,2292,490,2040,353,430,624,1245,38,2129,130,1475,501,720,1376,603,632,2756,2265,1498,3240,2041,149,1500,44,1611,1881,166,401,640,2594,1817,2131,1196,2731,1852,1636,674,655,1455,1730,1567,2132,2733,1212,641,568,2571,2596,1334,388,2075,2106,1146,254,2107,1618,2133,1478,595,540,2253,248,2692,533,1,2507,1001,112,618,300,733,573,231,2222,55,2769,1484,503,2115,207,892,1150,512,416,135,2580,1895,1803,1171,165,1689,1204,234,2464,289,59,1322,2617,1350,2233,281,1868,1117,136,1257,109,1296,1810,726
|
0.3852422065417807,-1.0113097535490851,-0.760651747905037,0.9058005368829619,-0.760651747905037,0.9058005368829619,0.1641085471368729,0.07909400602166337,0.9802563479044419,-0.2581525139593801,0.03614204326984603,-0.22807885031082178,-1.0113097535490851,-0.4885500586033537,-0.9772829358324227,1.222218044879942,-0.6955235731118161,-0.1535347647507937,0.6379588946017836,0.31698540656083257,0.7669425203474032,-0.3953451725415673,0.07909400602166337,0.5724477159799228,-0.3035420687482125,-0.45732323785786155,3.508477031496731,0.07909400602166337,0.5062366837929436,2.2592655177971985,1.1865154018947937,-0.24309720612430855,1.7674589112604508,-0.2581525139593801,-0.3035420687482125,-0.24309720612430855,0.46616755845459307,-0.2883747518392183,1.281273760705501,-0.5199376859291878,-1.0113097535490851,-1.20196329291841,2.8548455407684523,-0.13873418933689516,0.4123351763696069,-0.31874711143957013,-0.45732323785786155,0.9431396034941706,-0.31874711143957013,1.2340738196350072,1.0538338490539432,0.7413591680028151,0.12174807413919582,2.9005459852632884,-0.364590575074656,2.023358667895234,-0.021598244629604746,0.9182717672838793,0.6249119037114952,0.03614204326984603,0.779694821256333,0.7285278893546684,-0.7443040905812541,-0.44176959203476396,-0.03611853455253771,-1.362566906250655,-0.31874711143957013,1.9286049804157963,-0.03611853455253771,2.7903132643602064,-0.1092398235540067,-0.24309720612430855,1.8324111571270458,1.1385927506711437,0.7156700563298527,-0.647131625751063,-0.21309725685462735,-0.364590575074656,0.1641085471368729,-0.728000339684901,-0.22807885031082178,-0.12396926881478841,0.6769360722247575,0.6898742644114918,-0.007112210270966405,-0.16837117607596028,-0.07988664715431047,-0.364590575074656,-0.728000339684901,0.1500207496396212,0.7156700563298527,0.8177955706609692,-0.631086208801837,-0.647131625751063,0.06480999958601061,1.1625999707615722,-0.3339900772103585,-0.34927116493347793,0.20617963072146406,1.5120884232445022,-0.34927116493347793,-0.1092398235540067,-0.364590575074656,-0.021598244629604746,0.7924210222267182,0.8556644142476869,-0.42625550585234623,1.5347102368011099,-0.6955235731118161,0.8682363372946176,3.918017746429074,-0.5832023743822983,0.31698540656083257,2.1679949059006707,0.7541640070071953,1.3514137844149743,0.6118374126406803,0.8177955706609692,1.5909114869453034,-0.41078076891872717,2.6781524570436264,-0.7443040905812541,-0.021598244629604746,0.9182717672838793,-0.34927116493347793,1.6798031111121596,0.42583726441943925,0.20617963072146406,0.9058005368829619,1.0902999671477054,1.991931331193204,-0.631086208801837,-0.24309720612430855,-0.19815223757022424,0.19218783473832943,1.8431719091236531,-0.13873418933689516,0.1641085471368729,1.5909114869453034,-0.5514878660885424,1.3977418285889271,2.6498026320516255,0.07909400602166337,-0.647131625751063,0.06480999958601061,-0.41078076891872717,1.420778256383682,-0.22807885031082178,0.23406828346498643,1.991931331193204,0.12174807413919582,2.2087214952641787,0.09334491384878002,-0.19815223757022424,0.6249119037114952
| 3,376
|
Abnormal circulating cholesterol concentration
| 13
| 30
| 3.066704
| 0.002164
|
Q9NZJ7,P37268,Q9UJS0,O75431,Q8N511,Q15904,Q9H9E3,Q15392,P07602,Q15800,Q14739,P50402,Q9NVI7
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
173,238,437,240,83,595,187,87,469,126,347,220,446
|
240,1698,1427,469,238,3240,1704,950,220,2449,886,1455,1794,1215,2014,1820,347,87,658,126,595,83,1073,1222,1137,187,446,173,2347,437
|
1.5572509969346298,-0.1535347647507937,0.007339737540638098,0.9925796692463879,1.5684911717900816,-1.362566906250655,-0.1535347647507937,0.35802993391519033,1.6132522522142752,-0.5514878660885424,0.42583726441943925,-0.007112210270966405,-0.19815223757022424,0.1500207496396212,-0.3035420687482125,-0.21309725685462735,1.245907190269227,2.339309921504243,0.6898742644114918,2.0650208618258294,0.7924210222267182,2.3986898186378873,0.2618313464396684,0.1500207496396212,0.22013973023415834,1.7456588522658942,1.0416310057595912,1.8000185178422223,-0.4729166554316845,1.0538338490539432
| 3,376
|
Ragged red muscle fibers
| 7
| 18
| 3.06074
| 0.002208
|
P12235,P03886,Q9H2D1,Q9Y5P6,Q70HW3,P00846,P00403
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
97,68,15,341,248,28,95
|
2144,669,362,95,28,68,97,2322,2130,753,2074,248,2457,1483,1768,15,1155,341
|
-0.37994850970962596,0.6769360722247575,1.21033977687557,2.2693262981715874,3.0624281306689123,2.525480253725994,2.2592655177971985,-0.4729166554316845,-0.364590575074656,0.5856054418382873,-0.3339900772103585,1.5347102368011099,-0.5514878660885424,-0.021598244629604746,-0.1832436057353802,3.349044243996922,0.20617963072146406,1.2577182453742726
| 3,376
|
Endoplasmic reticulum tubular network
| 7
| 14
| 3.055833
| 0.002244
|
Q9NQC3,Q9H6H4,Q8NHH9,Q9H2C2,P61026,P50402,Q6NUK4
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
66,261,134,104,495,220,415
|
1323,220,495,558,2075,1733,909,415,134,1487,104,261,1774,66
|
0.06480999958601061,1.6132522522142752,0.9307180881219075,0.8304441394676204,-0.3339900772103585,-0.16837117607596028,0.39880353572925303,1.0902999671477054,1.991931331193204,-0.021598244629604746,2.2289873418727852,1.500746929971123,-0.1832436057353802,2.554385400886273
| 3,376
|
Nucleobase containing compound transmembrane transporter activity
| 8
| 15
| 3.055798
| 0.002245
|
P12235,Q9HC21,Q9BSK2,Q86VD7,Q6KCM7,L0R6Q1,Q9H2D1,Q8TB61
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
97,193,3,72,76,333,15,112
|
333,1189,727,609,97,375,3078,966,76,679,72,112,3,15,193
|
1.2695070730093605,0.1641085471368729,0.6118374126406803,0.7669425203474032,2.2592655177971985,1.1865154018947937,-1.0455292059601446,0.3443787137519083,2.428173597886573,0.6769360722247575,2.457521700066298,2.1679949059006707,3.8868120422021692,3.349044243996922,1.72378323442192
| 3,376
|
Oxidoreduction driven active transmembrane transporter activity
| 12
| 33
| 3.051298
| 0.002279
|
P51970,Q9UDW1,P03886,P13073,Q7KZN9,P00403,O95168,O43676,Q9Y6M9,P20674,Q9P0J0,O96000
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
538,36,68,100,572,95,343,25,282,317,93,30
|
1559,1243,763,25,1603,1812,566,1324,343,1561,1326,30,95,68,907,1909,100,3153,317,3006,1209,2408,3129,538,1435,731,2762,1822,572,93,36,1993,282
|
-0.07988664715431047,0.12174807413919582,0.5724477159799228,3.106682006127666,-0.1092398235540067,-0.21309725685462735,0.8177955706609692,0.06480999958601061,1.245907190269227,-0.07988664715431047,0.06480999958601061,3.0446410783605184,2.2693262981715874,2.525480253725994,0.39880353572925303,-0.2581525139593801,2.2390960928105765,-1.1668478915554994,1.30474106378976,-0.9603410571851295,0.1500207496396212,-0.5199376859291878,-1.1319358181488326,0.8556644142476869,0.007339737540638098,0.6118374126406803,-0.7443040905812541,-0.21309725685462735,0.8177955706609692,2.2793711942368797,2.9187354965517494,-0.2883747518392183,1.420778256383682
| 3,376
|
Electron transfer activity
| 17
| 57
| 3.050174
| 0.002287
|
P51970,Q9UDW1,P03886,P13073,P14406,O15121,P21912,O75306,P16435,Q7KZN9,P00403,O95168,O43676,Q9Y6M9,P20674,Q9P0J0,O96000
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
538,36,68,100,8,105,268,566,456,572,95,343,25,282,317,93,30
|
1559,1243,105,590,1299,763,25,1603,2316,1812,566,1324,343,1561,1326,30,1327,95,68,2169,907,1519,1909,1964,100,3137,8,2623,456,3153,317,268,2174,1848,3006,3093,2322,1209,3101,2408,710,3129,538,1435,2075,2043,731,1363,2762,1822,1858,572,93,36,1993,282,904
|
-0.07988664715431047,0.12174807413919582,2.21886249397109,0.7924210222267182,0.07909400602166337,0.5724477159799228,3.106682006127666,-0.1092398235540067,-0.4729166554316845,-0.21309725685462735,0.8177955706609692,0.06480999958601061,1.245907190269227,-0.07988664715431047,0.06480999958601061,3.0446410783605184,0.06480999958601061,2.2693262981715874,2.525480253725994,-0.3953451725415673,0.39880353572925303,-0.05067325033674048,-0.2581525139593801,-0.2883747518392183,2.2390960928105765,-1.1493665932391064,3.549788972453769,-0.6632195009402341,1.017153527787551,-1.1668478915554994,1.30474106378976,1.4551752366331643,-0.3953451725415673,-0.22807885031082178,-0.9603410571851295,-1.062711887611437,-0.4729166554316845,0.1500207496396212,-1.079943594085977,-0.5199376859291878,0.6379588946017836,-1.1319358181488326,0.8556644142476869,0.007339737540638098,-0.3339900772103585,-0.31874711143957013,0.6118374126406803,0.050492732938221645,-0.7443040905812541,-0.21309725685462735,-0.22807885031082178,0.8177955706609692,2.2793711942368797,2.9187354965517494,-0.2883747518392183,1.420778256383682,0.4123351763696069
| 3,376
|
Golgi apparatus
| 115
| 335
| 3.047683
| 0.002306
|
Q8N4V1,Q9Y3A6,O60499,Q9HD26,P80303,Q68CQ7,Q5VZ89,Q9P2W9,Q9Y3E0,Q9NR31,O95197,Q8NBN3,Q8NCH0,Q9NPR9,Q15836,Q9HC07,Q99805,P50897,P46934,Q16739,Q5VW38,Q93050,O43505,Q13464,O14773,P98194,O15258,Q96K37,O15126,Q15363,Q9H4A6,Q9Y282,Q92520,O15260,Q9H7Z7,Q15392,O95249,P35613,Q96RL7,O95070,P49755,Q9H2C2,Q14999,Q7LGA3,Q9NQX7,Q8TB61,O43752,P04062,Q9BRK5,Q9Y371,Q99523,Q9NX40,Q4J6C6,P35670,Q9NXE4,Q9H267,O00461,Q14108,Q9UID3,O43823,Q8IV08,P51572,Q96RQ1,Q96ED9,Q9BSL1,Q93063,P53367,P20337,Q7Z3D4,Q8NDZ4,Q9H9E3,Q96A57,Q9BSR8,Q9Y6Y8,Q8N3F8,P05067,Q8WVQ1,P10321,P05023,Q99640,Q9NX62,Q9C0D9,O75503,Q8IZA0,Q9BUR5,P16278,P50542,O43852,Q13190,Q969X5,Q9Y3B3,Q8NF37,P49257,L0R6Q1,Q02818,Q9Y2T2,Q8TD16,Q10713,Q9H3P7,Q8NBZ7,Q9BXS4,Q9UNK9,Q92544,Q14457,Q6ZRP7,O14735,Q9H0U4,Q9NTJ5,P04439,Q9BZG1,O15027,P61026,Q10472,O15118,P53365
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
1,520,11,526,19,20,532,22,547,546,29,32,34,35,559,43,46,47,557,51,52,55,553,569,61,568,565,586,579,73,74,75,77,79,599,87,88,603,96,99,610,104,616,110,111,112,116,118,119,638,636,123,634,632,667,666,146,147,150,651,158,673,168,172,691,690,686,685,180,181,187,186,703,717,200,204,205,708,707,212,219,239,241,253,275,273,286,302,304,311,320,332,331,333,344,370,372,388,396,404,423,428,435,440,442,448,471,472,468,477,486,495,496,506,507
|
333,2286,1903,1054,2202,146,2164,1811,2558,448,1394,61,1207,1601,486,506,579,856,565,79,1602,3245,553,3238,2061,116,2862,651,302,11,2167,1190,1451,2287,1605,1533,241,2492,3180,99,29,1473,88,1934,2354,1057,1587,963,2678,118,468,707,204,785,3362,1666,2288,2430,818,708,819,1355,273,2804,1935,2239,685,2035,947,3209,3173,2147,2591,2175,3216,2006,3232,1263,2499,1330,2293,1038,603,632,2265,2431,2208,2447,775,1704,1915,557,1916,2243,331,1126,610,2365,286,965,1705,47,2072,1613,2409,673,1104,847,1755,507,686,2471,1635,1160,1882,2295,2831,767,495,1637,2366,2810,2450,3361,1059,1918,1940,19,938,1310,568,2596,1794,2329,344,2812,1540,1215,496,1197,388,1130,2182,2246,1590,804,304,3346,569,2933,1382,2076,2896,147,2215,440,1271,2416,1060,3236,616,2274,1336,909,2837,73,87,1089,1337,559,51,1217,634,1824,2047,52,2302,532,1889,20,1179,1796,797,2082,1458,1021,2335,1710,442,3124,110,2386,180,2765,1272,1948,1644,2692,1645,1109,1596,1798,158,2421,1218,253,200,951,1,1220,32,404,34,1649,181,1316,332,112,372,3031,889,205,1981,77,1460,838,435,2085,2793,55,690,2136,1684,311,972,186,172,1074,586,891,1023,1740,840,96,168,808,1186,1112,636,2373,212,2639,46,3098,2794,3176,119,691,703,1114,1137,275,743,2859,1151,2280,2090,423,974,477,2116,239,2160,471,666,104,396,1772,74,599,1465,187,1077,43,526,1774,35,111,1990,546,1467,472,123,219,667,2394,2484,1276,22,1554,1389,1188,150,1241,2054,725,1009,3312,1717,3360,2313,1690,2800,1391,428,3324,2821,1809,841,1959,75,1229,2199,370,1657,638,1746,520,320,547,2885,842,1837,1747,717
|
1.2695070730093605,-0.45732323785786155,-0.2581525139593801,0.2756661511961478,-0.41078076891872717,1.939203453754038,-0.3953451725415673,-0.21309725685462735,-0.631086208801837,1.0294042647856594,0.021757766555510514,2.62132664953133,0.1500207496396212,-0.1092398235540067,0.9555364168366788,0.9058005368829619,0.8051212350176506,0.45275332185277023,0.8177955706609692,2.4183608115792006,-0.1092398235540067,-1.380679358108941,0.8304441394676204,-1.362566906250655,-0.3339900772103585,2.116716699323345,-0.8264864472557774,0.6898742644114918,1.3397781272483118,3.450194354038298,-0.3953451725415673,0.1641085471368729,-0.007112210270966405,-0.45732323785786155,-0.1092398235540067,-0.06526256357203314,1.5572509969346298,-0.5832023743822983,-1.2195980207013146,2.2390960928105765,3.0535407471601967,-0.021598244629604746,2.32935923806442,-0.27324496497470774,-0.4885500586033537,0.2756661511961478,-0.09454567529886222,0.3443787137519083,-0.6955235731118161,2.1064111698932244,0.9925796692463879,0.6379588946017836,1.6798031111121596,0.5460481617509392,-2.7625821237366743,-0.13873418933689516,-0.45732323785786155,-0.535692346636734,0.5062366837929436,0.6379588946017836,0.5062366837929436,0.050492732938221645,1.4437304908127628,-0.7770435603241972,-0.27324496497470774,-0.42625550585234623,0.6639708590611185,-0.31874711143957013,0.35802993391519033,-1.2906578721061541,-1.20196329291841,-0.37994850970962596,-0.647131625751063,-0.3953451725415673,-1.3085546915454922,-0.3035420687482125,-1.344508871789742,0.1075628834780911,-0.5832023743822983,0.06480999958601061,-0.45732323785786155,0.28946999971654247,0.779694821256333,0.7285278893546684,-0.44176959203476396,-0.535692346636734,-0.41078076891872717,-0.5514878660885424,0.5592619976723756,-0.1535347647507937,-0.2581525139593801,0.8304441394676204,-0.2581525139593801,-0.42625550585234623,1.281273760705501,0.22013973023415834,0.7669425203474032,-0.4885500586033537,1.3977418285889271,0.3443787137519083,-0.1535347647507937,2.743817956942605,-0.3339900772103585,-0.1092398235540067,-0.5199376859291878,0.6769360722247575,0.23406828346498643,0.46616755845459307,-0.1832436057353802,0.9058005368829619,0.6639708590611185,-0.5673244671099098,-0.12396926881478841,0.19218783473832943,-0.24309720612430855,-0.45732323785786155,-0.7934797786581159,0.5724477159799228,0.9307180881219075,-0.12396926881478841,-0.4885500586033537,-0.7770435603241972,-0.5514878660885424,-2.7397368521127348,0.2756661511961478,-0.2581525139593801,-0.27324496497470774,3.3064270469258985,0.3716510518956005,0.07909400602166337,0.8177955706609692,-0.647131625751063,-0.19815223757022424,-0.4729166554316845,1.245907190269227,-0.7770435603241972,-0.06526256357203314,0.1500207496396212,0.9307180881219075,0.1641085471368729,1.1625999707615722,0.22013973023415834,-0.3953451725415673,-0.42625550585234623,-0.09454567529886222,0.5195356321277029,1.3397781272483118,-2.0518203246758446,0.8177955706609692,-0.8763358915188677,0.03614204326984603,-0.3339900772103585,-0.8430574101429883,1.939203453754038,-0.41078076891872717,1.0416310057595912,0.1075628834780911,-0.5199376859291878,0.2756661511961478,-1.344508871789742,0.7541640070071953,-0.44176959203476396,0.06480999958601061,0.39880353572925303,-0.7934797786581159,2.4477539937687958,2.339309921504243,0.2479654395213026,0.06480999958601061,0.8304441394676204,2.706377290804834,0.1500207496396212,0.7285278893546684,-0.21309725685462735,-0.31874711143957013,2.6875745657573895,-0.45732323785786155,0.8682363372946176,-0.24309720612430855,3.237649451673598,0.17816419100440917,-0.19815223757022424,0.5328060821965044,-0.3339900772103585,-0.007112210270966405,0.3032430368863615,-0.4729166554316845,-0.1535347647507937,1.0416310057595912,-1.1145552610735343,2.1883908286935503,-0.5042236629761834,1.7674589112604508,-0.7443040905812541,0.1075628834780911,-0.27324496497470774,-0.12396926881478841,-0.6955235731118161,-0.12396926881478841,0.23406828346498643,-0.09454567529886222,-0.19815223757022424,1.8753446974883117,-0.5199376859291878,0.1500207496396212,1.5234094998830219,1.7018315064972644,0.35802993391519033,3.918017746429074,0.1500207496396212,3.0357290886065282,1.1385927506711437,2.927810977237293,-0.12396926881478841,1.7674589112604508,0.07909400602166337,1.281273760705501,2.1679949059006707,1.1984389259522672,-0.9772829358324227,0.42583726441943925,1.6798031111121596,-0.2883747518392183,2.428173597886573,-0.007112210270966405,0.4795527769199012,1.0538338490539432,-0.3339900772103585,-0.760651747905037,2.6781524570436264,0.6639708590611185,-0.364590575074656,-0.13873418933689516,1.3281208444722734,0.3443787137519083,1.7456588522658942,1.8000185178422223,0.2618313464396684,0.8051212350176506,0.42583726441943925,0.3032430368863615,-0.16837117607596028,0.4795527769199012,2.2693262981715874,1.8216320518149403,0.5195356321277029,0.17816419100440917,0.23406828346498643,0.7285278893546684,-0.4885500586033537,1.6576974846458383,-0.6632195009402341,2.781041140569378,-1.062711887611437,-0.760651747905037,-1.20196329291841,2.1064111698932244,0.6639708590611185,0.6509785063189131,0.23406828346498643,0.22013973023415834,1.4437304908127628,0.5987352995655117,-0.8099606559026915,0.20617963072146406,-0.44176959203476396,-0.3339900772103585,1.0781682329246185,0.3443787137519083,0.9802563479044419,-0.34927116493347793,1.5684911717900816,-0.37994850970962596,0.9925796692463879,0.6898742644114918,2.2289873418727852,1.1506078804869229,-0.1832436057353802,2.437971309123152,0.7924210222267182,-0.007112210270966405,1.7456588522658942,0.2618313464396684,2.8088173906325995,0.8807829276640542,-0.1832436057353802,2.927810977237293,2.1782010517657495,-0.2883747518392183,0.8556644142476869,-0.007112210270966405,0.9925796692463879,2.0960888788447267,1.6243929881344374,0.6898742644114918,-0.5042236629761834,-0.5673244671099098,0.1075628834780911,3.1942884268912617,-0.06526256357203314,0.03614204326984603,0.17816419100440917,1.9286049804157963,0.13590064389229117,-0.31874711143957013,0.6249119037114952,0.31698540656083257,-1.678171482939842,-0.1535347647507937,-2.716980039772484,-0.45732323785786155,-0.13873418933689516,-0.760651747905037,0.03614204326984603,1.0660128924007646,-1.75491299162932,-0.7770435603241972,-0.19815223757022424,0.4795527769199012,-0.27324496497470774,2.437971309123152,0.1500207496396212,-0.3953451725415673,1.21033977687557,-0.12396926881478841,0.7285278893546684,-0.16837117607596028,0.8933042921551931,1.30474106378976,0.8556644142476869,-0.8264864472557774,0.4795527769199012,-0.21309725685462735,-0.16837117607596028,0.6379588946017836
| 3,376
|
Areflexia of lower limbs
| 12
| 25
| 3.046488
| 0.002315
|
Q96RL7,O95394,P12235,Q15067,Q16637,O95140,Q13501,O60313,Q9NR77,Q15041,Q15120,Q9H6K4
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
96,695,97,255,549,670,711,236,31,508,698,160
|
236,1373,991,670,695,1262,97,2565,965,753,1564,1852,2210,1759,711,508,255,698,549,1737,96,1483,160,31,1718
|
1.5797113102117606,0.03614204326984603,0.31698540656083257,0.6769360722247575,0.6509785063189131,0.1075628834780911,2.2592655177971985,-0.631086208801837,0.3443787137519083,0.5856054418382873,-0.07988664715431047,-0.22807885031082178,-0.41078076891872717,-0.1832436057353802,0.6379588946017836,0.9058005368829619,1.5120884232445022,0.6509785063189131,0.8430670510338878,-0.16837117607596028,2.2693262981715874,-0.021598244629604746,1.8646386144308038,3.0446410783605184,-0.1535347647507937
| 3,376
|
Glycerophospholipid biosynthesis
| 17
| 29
| 3.038742
| 0.002376
|
Q53H12,O14735,Q96N66,Q8NF37,Q8IV08,Q8WWI5,Q8NCC3,Q9UG56,P48651,Q99829,Q9C0D9,P43304,Q92604,O15228,Q9NPH0,Q9HCL2,P40939
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
290,448,225,332,158,573,689,528,141,742,239,633,663,529,24,27,794
|
448,529,2000,2682,897,794,633,141,2243,3079,1309,290,1621,158,689,332,1763,573,663,225,742,986,810,2229,239,27,24,1553,528
|
1.0294042647856594,0.8682363372946176,-0.3035420687482125,-0.6955235731118161,0.4123351763696069,0.5328060821965044,0.7285278893546684,1.970892831816529,-0.42625550585234623,-1.0455292059601446,0.07909400602166337,1.386191839289798,-0.1092398235540067,1.8753446974883117,0.6639708590611185,1.281273760705501,-0.1832436057353802,0.8177955706609692,0.6898742644114918,1.602091776312444,0.5987352995655117,0.3306972515746962,0.5195356321277029,-0.41078076891872717,1.5684911717900816,3.097855519585872,3.141867551624668,-0.06526256357203314,0.8807829276640542
| 3,376
|
Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen
| 10
| 32
| 3.02243
| 0.002508
|
Q16850,Q8N543,P30519,P09601,O15121,Q9NVH6,Q6UW02,Q86SK9,Q14534,Q15800
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
65,390,38,9,105,203,54,280,153,126
|
1997,960,105,590,1869,2167,1099,1302,9,766,456,38,937,2687,2075,153,126,65,1443,2872,1458,54,2155,280,1646,390,1648,3249,2309,203,1255,2703
|
-0.3035420687482125,0.3443787137519083,2.21886249397109,0.7924210222267182,-0.24309720612430855,-0.3953451725415673,0.23406828346498643,0.07909400602166337,3.508477031496731,0.5724477159799228,1.017153527787551,2.9005459852632884,0.3716510518956005,-0.6955235731118161,-0.3339900772103585,1.8967026461556973,2.0650208618258294,2.554385400886273,0.007339737540638098,-0.8264864472557774,-0.007112210270966405,2.6781524570436264,-0.37994850970962596,1.420778256383682,-0.12396926881478841,1.1625999707615722,-0.12396926881478841,-1.380679358108941,-0.45732323785786155,1.6908269273161953,0.12174807413919582,-0.6955235731118161
| 3,376
|
Sphingolipid metabolism in senescence
| 6
| 14
| 3.012687
| 0.002589
|
Q96G23,Q06136,O15121,Q13510,Q16739,P04062
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
163,103,105,175,51,118
|
105,521,118,1783,648,273,1910,1193,2006,775,103,175,51,163
|
2.21886249397109,0.8807829276640542,2.1064111698932244,-0.19815223757022424,0.7027855534353731,1.4437304908127628,-0.2581525139593801,0.1641085471368729,-0.3035420687482125,0.5592619976723756,2.2289873418727852,1.789183956579087,2.706377290804834,1.8431719091236531
| 3,376
|
Mitochondrial carrier protein [IPR002067]
| 11
| 13
| 3.008398
| 0.002626
|
Q9BQT8,Q6NUK1,Q9HC21,P05141,P12235,Q86VD7,P53007,O75746,Q6KCM7,Q9UJS0,P12236
|
Sequence
|
InterPro Family
|
interpro_family
|
475,679,193,609,97,72,425,489,76,437,375
|
727,489,609,97,375,425,76,679,72,475,1171,193,437
|
0.6118374126406803,0.9431396034941706,0.7669425203474032,2.2592655177971985,1.1865154018947937,1.0660128924007646,2.428173597886573,0.6769360722247575,2.457521700066298,0.9802563479044419,0.19218783473832943,1.72378323442192,1.0538338490539432
| 3,376
|
Monovalent inorganic cation homeostasis
| 15
| 28
| 3.007335
| 0.002635
|
Q9Y5X3,Q9HC07,Q9Y487,P05023,Q9Y6M7,Q93063,P50897,Q92544,Q05086,Q8N511,Q15904,Q93050,O75503,P06576,P61421
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
392,43,109,707,726,690,47,435,740,83,595,55,241,751,655
|
241,991,1374,707,993,751,818,2175,2006,47,2072,2131,1196,655,740,595,83,435,55,690,1685,43,1188,1350,109,392,3037,726
|
1.5572509969346298,0.31698540656083257,0.03614204326984603,0.6379588946017836,0.31698540656083257,0.5856054418382873,0.5062366837929436,-0.3953451725415673,-0.3035420687482125,2.743817956942605,-0.3339900772103585,-0.364590575074656,0.1641085471368729,0.6898742644114918,0.5987352995655117,0.7924210222267182,2.3986898186378873,1.0538338490539432,2.6781524570436264,0.6639708590611185,-0.13873418933689516,2.8088173906325995,0.17816419100440917,0.06480999958601061,2.2087214952641787,1.1625999707615722,-0.9772829358324227,0.6249119037114952
| 3,376
|
Sphingolipid metabolism
| 9
| 13
| 2.999676
| 0.002703
|
Q06136,O43681,O15121,Q13510,Q16739,P16278,P04062,Q9NRA0,O95470
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
103,137,105,175,51,273,118,407,315
|
105,521,1781,137,315,118,785,273,103,175,51,407,667
|
2.21886249397109,0.8807829276640542,-0.19815223757022424,1.9814208160018005,1.30474106378976,2.1064111698932244,0.5460481617509392,1.4437304908127628,2.2289873418727852,1.789183956579087,2.706377290804834,1.126554488303031,0.6898742644114918
| 3,376
|
Abnormal biliary tract morphology
| 11
| 25
| 2.988572
| 0.002803
|
P50542,P14174,Q10713,O43933,P09601,O43681,Q9NZJ7,Q14108,P04062,P07602,Q14739
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
286,481,388,513,9,137,173,147,118,469,347
|
137,513,1698,118,469,9,481,2848,2432,2685,286,1358,753,388,1162,147,347,585,1683,1047,1026,173,1490,1155,781
|
1.9814208160018005,0.8933042921551931,-0.1535347647507937,2.1064111698932244,0.9925796692463879,3.508477031496731,0.9679086309299181,-0.8099606559026915,-0.535692346636734,-0.6955235731118161,1.3977418285889271,0.050492732938221645,0.5856054418382873,1.1625999707615722,0.19218783473832943,1.939203453754038,1.245907190269227,0.8051212350176506,-0.13873418933689516,0.28946999971654247,0.3032430368863615,1.8000185178422223,-0.021598244629604746,0.20617963072146406,0.5592619976723756
| 3,376
|
primary active transporter
| 11
| 23
| 2.987283
| 0.002815
|
Q9BUN8,Q9NS69,O60888,Q8N4H5,Q9Y5J7,O96008,P16615,Q15388,Q6P4A7,P35670,P98194
|
Functions
|
Panther Protein class
|
panther_protein_class
|
416,2,131,12,429,523,178,242,152,632,568
|
131,1325,523,707,993,1874,178,845,632,2131,568,242,1478,152,12,2387,1024,416,1895,1346,2344,2,429
|
2.012900196950257,0.06480999958601061,0.8807829276640542,0.6379588946017836,0.31698540656083257,-0.24309720612430855,1.7674589112604508,0.46616755845459307,0.7285278893546684,-0.364590575074656,0.8177955706609692,1.5572509969346298,-0.021598244629604746,1.9073546394248442,3.4250546344122745,-0.5042236629761834,0.3032430368863615,1.0902999671477054,-0.24309720612430855,0.06480999958601061,-0.4729166554316845,3.918017746429074,1.0660128924007646
| 3,376
|
Serine hydrolase activity
| 10
| 17
| 2.981406
| 0.002869
|
P42785,P10619,Q9HB40,P67812,O75976,Q5JRX3,Q9H3G5,O43464,O14773,P48147
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
378,132,227,7,554,381,576,530,61,474
|
61,530,554,132,1751,2128,2432,378,474,1105,7,1887,634,381,999,576,227
|
2.62132664953133,0.8682363372946176,0.8304441394676204,2.012900196950257,-0.1832436057353802,-0.364590575074656,-0.535692346636734,1.1745691139378525,0.9802563479044419,0.23406828346498643,3.6071872129131113,-0.24309720612430855,0.7285278893546684,1.1745691139378525,0.31698540656083257,0.8177955706609692,1.602091776312444
| 3,376
|
Mitochondrial complex iv assembly
| 8
| 16
| 2.978215
| 0.002899
|
Q96I36,P13073,P14406,Q9Y2R0,Q9P0S2,Q7KZN9,P20674,P00403
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
517,100,8,10,139,572,317,95
|
1559,602,95,1909,100,8,1175,317,731,572,517,1318,139,943,10,904
|
-0.07988664715431047,0.779694821256333,2.2693262981715874,-0.2581525139593801,2.2390960928105765,3.549788972453769,0.17816419100440917,1.30474106378976,0.6118374126406803,0.8177955706609692,0.8933042921551931,0.07909400602166337,1.9814208160018005,0.3716510518956005,3.491878261337632,0.4123351763696069
| 3,376
|
Cytoprotection by hmox1
| 18
| 68
| 2.971134
| 0.002967
|
P28070,P13073,P30519,P49721,P20618,P09601,Q92530,O75376,Q9P0S2,O00487,P51665,Q99436,P28072,Q9UL46,Q8TCT9,O75880,P20674,P00403
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
353,100,38,166,330,9,231,267,139,505,401,503,430,281,122,188,317,95
|
921,3046,2779,1559,505,1243,2780,1300,602,267,1843,188,95,9,1909,100,1175,1877,2682,330,317,1669,895,2038,2292,2040,353,430,624,38,2756,3336,2913,1500,1611,1881,166,401,1501,2731,1636,674,1730,1567,2132,1212,1309,1334,2106,2542,2107,2896,1283,1618,2133,731,1180,122,231,517,2461,503,2115,1318,139,281,1868,904
|
0.3852422065417807,-1.0113097535490851,-0.760651747905037,-0.07988664715431047,0.9058005368829619,0.12174807413919582,-0.760651747905037,0.07909400602166337,0.779694821256333,1.4551752366331643,-0.22807885031082178,1.7347305225090166,2.2693262981715874,3.508477031496731,-0.2581525139593801,2.2390960928105765,0.17816419100440917,-0.24309720612430855,-0.6955235731118161,1.281273760705501,1.30474106378976,-0.13873418933689516,0.4123351763696069,-0.31874711143957013,-0.45732323785786155,-0.31874711143957013,1.2340738196350072,1.0538338490539432,0.7413591680028151,2.9005459852632884,-0.7443040905812541,-1.911420416598596,-0.8596738042439521,-0.03611853455253771,-0.1092398235540067,-0.24309720612430855,1.8324111571270458,1.1385927506711437,-0.03611853455253771,-0.728000339684901,-0.12396926881478841,0.6769360722247575,-0.16837117607596028,-0.07988664715431047,-0.364590575074656,0.1500207496396212,0.07909400602166337,0.06480999958601061,-0.34927116493347793,-0.6150830158119736,-0.34927116493347793,-0.8430574101429883,0.09334491384878002,-0.1092398235540067,-0.364590575074656,0.6118374126406803,0.17816419100440917,2.0960888788447267,1.5909114869453034,0.8933042921551931,-0.5514878660885424,0.9182717672838793,-0.34927116493347793,0.07909400602166337,1.9814208160018005,1.420778256383682,-0.22807885031082178,0.4123351763696069
| 3,376
|
Nucleotide transport
| 11
| 15
| 2.966019
| 0.003017
|
Q6NUK1,Q9HC21,P05141,Q9BSK2,P12235,Q86VD7,Q8TDW0,Q6KCM7,Q9H2D1,Q8TB61,P12236
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
679,193,609,3,97,72,618,76,15,112,375
|
1189,727,609,97,375,3078,1214,76,679,72,112,618,3,15,193
|
0.1641085471368729,0.6118374126406803,0.7669425203474032,2.2592655177971985,1.1865154018947937,-1.0455292059601446,0.1500207496396212,2.428173597886573,0.6769360722247575,2.457521700066298,2.1679949059006707,0.7541640070071953,3.8868120422021692,3.349044243996922,1.72378323442192
| 3,376
|
Secretory granule membrane
| 21
| 73
| 2.955058
| 0.003126
|
P42785,Q969Q5,Q9Y2Q5,Q4KMQ2,P30519,Q9NZJ7,Q93050,O00264,Q8NF37,O15126,Q15363,P10253,O15260,P07602,Q07065,P35613,O15121,P27105,P61026,Q9NQX7,Q5T9A4
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
378,16,285,540,38,173,55,198,332,579,73,329,79,469,89,603,105,490,495,111,509
|
2645,198,105,579,79,1189,2377,1190,694,2000,2491,991,3020,963,469,329,708,877,1355,3224,934,1398,2035,490,38,2129,1968,603,2069,378,1970,610,1754,2072,1104,2471,1971,495,1637,1972,3263,1940,1402,1674,89,1214,2330,1071,2250,2077,2273,73,540,3227,509,1890,332,1221,838,55,16,1985,742,974,2580,1774,111,173,2484,2617,285,1810,1531
|
-0.6793500706356256,1.7018315064972644,2.21886249397109,0.8051212350176506,2.4183608115792006,0.1641085471368729,-0.5042236629761834,0.1641085471368729,0.6509785063189131,-0.3035420687482125,-0.5832023743822983,0.31698540656083257,-0.9772829358324227,0.3443787137519083,0.9925796692463879,1.281273760705501,0.6379588946017836,0.42583726441943925,0.050492732938221645,-1.3265049130332804,0.3716510518956005,0.021757766555510514,-0.31874711143957013,0.9431396034941706,2.9005459852632884,-0.364590575074656,-0.2883747518392183,0.779694821256333,-0.3339900772103585,1.1745691139378525,-0.2883747518392183,0.7669425203474032,-0.1832436057353802,-0.3339900772103585,0.23406828346498643,-0.5673244671099098,-0.2883747518392183,0.9307180881219075,-0.12396926881478841,-0.2883747518392183,-1.4353466847464749,-0.27324496497470774,0.021757766555510514,-0.13873418933689516,2.32935923806442,0.1500207496396212,-0.4729166554316845,0.2618313464396684,-0.42625550585234623,-0.3339900772103585,-0.44176959203476396,2.4477539937687958,0.8556644142476869,-1.3265049130332804,0.9058005368829619,-0.24309720612430855,1.281273760705501,0.1500207496396212,0.4795527769199012,2.6781524570436264,3.3405432490399405,-0.2883747518392183,0.5987352995655117,0.3443787137519083,-0.631086208801837,-0.1832436057353802,2.1782010517657495,1.8000185178422223,-0.5673244671099098,-0.647131625751063,1.4092706071160868,-0.19815223757022424,-0.05067325033674048
| 3,376
|
Tclin
| 19
| 89
| 2.952711
| 0.00315
|
P31350,P00813,O43676,Q9Y6M9,O96000,P21964,P38435,Q99720,P49721,P20839,Q16739,Q06203,Q86Y39,P03886,P20618,P10253,O95168,Q9P0J0,P04035
|
Drugs and Diseases
|
Pharos IDG Category
|
pharos_protein_category
|
262,138,25,282,30,159,162,164,166,303,51,308,62,68,330,329,343,93,251
|
1559,763,25,1603,1425,1812,566,1324,343,1561,1326,30,764,1327,2803,138,68,251,1068,707,993,2169,946,785,979,2846,2319,1785,329,2650,2146,3164,2890,648,719,802,2623,3153,330,303,159,2173,1787,1669,2652,624,3006,1633,262,2208,162,775,3140,166,3129,1159,786,1431,538,2131,1196,1435,1213,1018,924,2329,308,1675,569,1019,1569,1283,2762,51,1822,1795,367,62,2219,1892,164,2089,1486,2227,1254,2745,93,1993,282
|
-0.07988664715431047,0.5724477159799228,3.106682006127666,-0.1092398235540067,0.007339737540638098,-0.21309725685462735,0.8177955706609692,0.06480999958601061,1.245907190269227,-0.07988664715431047,0.06480999958601061,3.0446410783605184,0.5724477159799228,0.06480999958601061,-0.7770435603241972,1.9814208160018005,2.525480253725994,1.5234094998830219,0.2618313464396684,0.6379588946017836,0.31698540656083257,-0.3953451725415673,0.35802993391519033,0.5460481617509392,0.3306972515746962,-0.8099606559026915,-0.4729166554316845,-0.19815223757022424,1.281273760705501,-0.6793500706356256,-0.37994850970962596,-1.1843800211435078,-0.8430574101429883,0.7027855534353731,0.6249119037114952,0.5195356321277029,-0.6632195009402341,-1.1668478915554994,1.281273760705501,1.3397781272483118,1.8646386144308038,-0.3953451725415673,-0.19815223757022424,-0.13873418933689516,-0.6793500706356256,0.7413591680028151,-0.9603410571851295,-0.12396926881478841,1.4780023836394796,-0.41078076891872717,1.8431719091236531,0.5592619976723756,-1.1493665932391064,1.8324111571270458,-1.1319358181488326,0.19218783473832943,0.5460481617509392,0.007339737540638098,0.8556644142476869,-0.364590575074656,0.1641085471368729,0.007339737540638098,0.1500207496396212,0.3032430368863615,0.3852422065417807,-0.4729166554316845,1.3281208444722734,-0.13873418933689516,0.8177955706609692,0.3032430368863615,-0.07988664715431047,0.09334491384878002,-0.7443040905812541,2.706377290804834,-0.21309725685462735,-0.19815223757022424,1.21033977687557,2.62132664953133,-0.41078076891872717,-0.24309720612430855,1.8431719091236531,-0.3339900772103585,-0.021598244629604746,-0.41078076891872717,0.12174807413919582,-0.728000339684901,2.2793711942368797,-0.2883747518392183,1.420778256383682
| 3,376
|
Calcium ion transport
| 18
| 60
| 2.950352
| 0.003174
|
Q9BPX6,Q4KMQ2,O95202,O75844,P21796,Q9HC07,P11413,Q9NVV0,Q6KCM7,O76024,Q96GC9,P30536,P78417,P16615,Q8IYU8,Q9NRA0,Q13555,Q08209
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
512,540,358,71,41,43,393,170,76,327,78,334,402,178,533,407,254,379
|
1054,1034,2377,1905,71,327,358,1374,993,2965,2207,2002,1785,2100,393,1727,178,1910,2005,934,3139,845,41,2240,2653,334,2129,1497,1704,1433,803,3263,1437,1379,402,568,1438,2573,379,3317,254,2478,540,76,1249,2635,533,1001,733,1576,78,1686,512,43,407,170,2233,1599,1690,1296
|
0.2756661511961478,0.28946999971654247,-0.5042236629761834,-0.2581525139593801,2.457521700066298,1.281273760705501,1.222218044879942,0.03614204326984603,0.31698540656083257,-0.9097982049966251,-0.41078076891872717,-0.3035420687482125,-0.19815223757022424,-0.34927116493347793,1.1506078804869229,-0.16837117607596028,1.7674589112604508,-0.2581525139593801,-0.3035420687482125,0.3716510518956005,-1.1493665932391064,0.46616755845459307,2.8548455407684523,-0.42625550585234623,-0.6793500706356256,1.2695070730093605,-0.364590575074656,-0.03611853455253771,-0.1535347647507937,0.007339737540638098,0.5195356321277029,-1.4353466847464749,0.007339737540638098,0.03614204326984603,1.1385927506711437,0.8177955706609692,0.007339737540638098,-0.631086208801837,1.1745691139378525,-1.7356350214699037,1.5120884232445022,-0.5673244671099098,0.8556644142476869,2.428173597886573,0.12174807413919582,-0.6632195009402341,0.8682363372946176,0.31698540656083257,0.6118374126406803,-0.07988664715431047,2.428173597886573,-0.13873418933689516,0.9058005368829619,2.8088173906325995,1.126554488303031,1.8216320518149403,-0.41078076891872717,-0.09454567529886222,-0.13873418933689516,0.09334491384878002
| 3,376
|
Transport vesicle
| 32
| 94
| 2.946257
| 0.003216
|
Q9BT78,O60499,Q9HD26,O00461,P61421,Q9NR31,Q92905,Q15836,P50897,Q13190,P20337,Q96A57,Q9Y3B3,Q9Y6Y8,O15126,P49257,Q15363,P05067,P10321,O76024,O15260,O43760,Q9H0U4,P04439,O95249,P49755,O15027,Q7L0J3,P61026,O43752,Q9GZY8,Q99523
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
525,11,526,146,655,546,422,559,47,304,685,186,320,717,579,331,73,204,708,327,79,84,471,468,88,610,486,367,495,116,373,636
|
1054,146,1811,3060,486,579,79,1298,1602,2061,116,84,2490,11,1451,2287,2144,1533,327,1722,88,1844,1963,2678,468,204,2288,2430,1785,708,877,1355,845,685,1815,2035,947,2240,2537,1038,2041,1916,331,610,47,2072,1613,2409,1104,2471,1635,2326,2831,1971,495,1637,655,2366,2810,1059,2596,1130,304,1071,2933,3083,1284,2017,2837,73,1089,2298,559,1179,367,1109,838,422,186,636,525,743,373,471,526,546,1467,1554,1835,1188,1229,320,1747,717
|
0.2756661511961478,1.939203453754038,-0.21309725685462735,-1.0283952575793793,0.9555364168366788,0.8051212350176506,2.4183608115792006,0.07909400602166337,-0.1092398235540067,-0.3339900772103585,2.116716699323345,2.3789579376592007,-0.5832023743822983,3.450194354038298,-0.007112210270966405,-0.45732323785786155,-0.37994850970962596,-0.06526256357203314,1.281273760705501,-0.16837117607596028,2.32935923806442,-0.22807885031082178,-0.2883747518392183,-0.6955235731118161,0.9925796692463879,1.6798031111121596,-0.45732323785786155,-0.535692346636734,-0.19815223757022424,0.6379588946017836,0.42583726441943925,0.050492732938221645,0.46616755845459307,0.6639708590611185,-0.21309725685462735,-0.31874711143957013,0.35802993391519033,-0.42625550585234623,-0.6150830158119736,0.28946999971654247,-0.31874711143957013,-0.2581525139593801,1.281273760705501,0.7669425203474032,2.743817956942605,-0.3339900772103585,-0.1092398235540067,-0.5199376859291878,0.23406828346498643,-0.5673244671099098,-0.12396926881478841,-0.4729166554316845,-0.7934797786581159,-0.2883747518392183,0.9307180881219075,-0.12396926881478841,0.6898742644114918,-0.4885500586033537,-0.7770435603241972,0.2756661511961478,-0.647131625751063,0.22013973023415834,1.3397781272483118,0.2618313464396684,-0.8763358915188677,-1.0455292059601446,0.09334491384878002,-0.3035420687482125,-0.7934797786581159,2.4477539937687958,0.2479654395213026,-0.45732323785786155,0.8304441394676204,0.17816419100440917,1.21033977687557,0.23406828346498643,0.4795527769199012,1.0781682329246185,1.7456588522658942,0.7285278893546684,0.8807829276640542,0.5987352995655117,1.1984389259522672,0.9925796692463879,0.8807829276640542,0.8556644142476869,-0.007112210270966405,-0.06526256357203314,-0.21309725685462735,0.17816419100440917,0.1500207496396212,1.30474106378976,-0.16837117607596028,0.6379588946017836
| 3,376
|
Ceramide biosynthetic process
| 9
| 12
| 2.94318
| 0.003249
|
Q53H12,Q96G23,O15121,Q13510,O15269,Q16739,P04062,Q9NRA0,Q9NTG7
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
290,163,105,175,521,51,118,407,351
|
105,521,1781,118,1269,175,51,290,163,407,351,667
|
2.21886249397109,0.8807829276640542,-0.19815223757022424,2.1064111698932244,0.1075628834780911,1.789183956579087,2.706377290804834,1.386191839289798,1.8431719091236531,1.126554488303031,1.245907190269227,0.6898742644114918
| 3,376
|
mitochondrial carrier protein
| 6
| 9
| 2.939886
| 0.003283
|
Q9HC21,Q9BSK2,Q86VD7,Q9NZJ7,Q6KCM7,Q9Y6C9
|
Functions
|
Panther Protein class
|
panther_protein_class
|
193,3,72,173,76,120
|
869,76,679,248,72,3,193,173,120
|
0.4393099348893643,2.428173597886573,0.6769360722247575,1.5347102368011099,2.457521700066298,3.8868120422021692,1.72378323442192,1.8000185178422223,2.1064111698932244
| 3,376
|
Protein transmembrane import into intracellular organelle
| 10
| 15
| 2.936769
| 0.003317
|
O60830,P50542,O43615,O43933,Q99595,Q96DA6,O96008,O95831,Q15388,O14925
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
0,286,356,513,4,563,523,362,242,156
|
156,356,513,0,1325,362,523,3062,286,242,604,2387,563,4,2344
|
1.8860326867293702,1.222218044879942,0.8933042921551931,3.918017746429074,0.06480999958601061,1.21033977687557,0.8807829276640542,-1.0283952575793793,1.3977418285889271,1.5572509969346298,0.779694821256333,-0.5042236629761834,0.8304441394676204,3.8081377581322435,-0.4729166554316845
| 3,376
|
Translocation
| 15
| 48
| 2.933035
| 0.003357
|
O60830,Q9NS69,Q99595,O43615,Q96DA6,Q9Y5L4,Q9Y5J7,Q99442,Q9BTX1,Q8TD16,Q15629,Q9Y5J9,O14925,Q8N1F7,Q3ZCQ8
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
0,2,4,356,563,668,429,534,340,372,85,157,156,510,604
|
1996,156,1532,356,0,2168,1874,1792,1634,820,3094,1357,1105,886,2968,1437,1729,1504,828,85,604,1248,1823,1509,510,1289,1167,372,1951,1168,3282,681,563,1184,534,824,4,340,2641,1275,894,2,2799,2673,2261,429,157,668
|
-0.3035420687482125,1.8860326867293702,-0.06526256357203314,1.222218044879942,3.918017746429074,-0.3953451725415673,-0.24309720612430855,-0.19815223757022424,-0.12396926881478841,0.5062366837929436,-1.062711887611437,0.050492732938221645,0.23406828346498643,0.42583726441943925,-0.9097982049966251,0.007339737540638098,-0.16837117607596028,-0.03611853455253771,0.49290910856241765,2.3789579376592007,0.779694821256333,0.12174807413919582,-0.21309725685462735,-0.03611853455253771,0.9058005368829619,0.09334491384878002,0.19218783473832943,1.1984389259522672,-0.27324496497470774,0.19218783473832943,-1.546198254920374,0.6769360722247575,0.8304441394676204,0.17816419100440917,0.8682363372946176,0.5062366837929436,3.8081377581322435,1.2577182453742726,-0.6632195009402341,0.1075628834780911,0.42583726441943925,3.918017746429074,-0.760651747905037,-0.6793500706356256,-0.42625550585234623,1.0660128924007646,1.8860326867293702,0.6898742644114918
| 3,376
|
Endomembrane system organization
| 76
| 195
| 2.931325
| 0.003375
|
P61019,Q8N4V1,Q9Y3A6,Q9H6H4,Q8NHH9,Q9Y2U8,O43681,Q9NPA0,Q9NXE4,Q9H267,Q14108,Q9P2W9,Q9UID3,Q5JRA6,P46379,O95197,Q6NUK4,Q4KMQ2,P50542,O94901,Q9P253,Q9H6U6,Q7L5D6,Q9NVV0,Q96CP7,Q96ED9,Q00765,Q2M389,P16615,Q16739,Q7Z3D4,Q13190,Q9H9E3,Q86XL3,P49069,Q9BSR8,O14657,Q9Y3B3,Q9NQC3,Q9UH99,Q9Y6Y8,Q96MW5,Q9Y5P4,O75844,Q8N3F8,Q15363,Q9H4A6,Q13501,A5D8V6,P49257,Q96GC9,O15260,Q8N5M9,O43760,Q15629,P57088,P50402,Q9ULX6,Q12768,P49755,O15027,Q9H2C2,Q14999,Q8IXJ6,O15121,Q9BVK6,P61026,P31751,Q53FT3,Q96A33,O43752,Q9UL15,Q9Y371,Q9H9H4,Q15041,Q8N1F7
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
767,1,520,261,134,780,137,397,667,666,147,22,150,796,409,29,415,540,286,537,814,811,296,170,171,172,558,688,178,51,180,304,187,305,431,703,182,320,66,197,717,840,842,71,200,73,74,711,577,331,78,79,209,84,85,470,220,737,222,610,486,104,616,106,105,743,495,113,498,243,116,374,638,771,508,510
|
1393,577,2645,3038,1054,2164,2558,182,1394,2513,1352,1601,486,105,79,1662,2124,1586,137,116,84,1098,1695,2287,1605,2491,1426,1533,2442,2168,71,1534,537,1722,29,1934,963,1698,1518,2207,178,1910,3039,1632,2147,2175,2006,113,1210,2208,2447,3078,1704,1793,409,1915,1430,431,331,610,220,286,965,2072,1673,2244,470,2295,767,1971,495,1437,1059,1615,938,558,2271,2329,1540,222,1130,2246,2367,304,1071,711,147,1760,969,1060,616,2601,508,909,3212,2836,73,85,51,688,540,498,1133,796,1944,997,2047,1890,415,296,2386,180,2765,1948,1645,305,2421,106,1408,510,200,951,1,209,1200,1649,2575,134,2306,1623,1460,2767,2085,1110,243,171,172,78,1074,840,1462,3098,2794,1225,1414,703,1114,1137,743,1487,666,104,864,74,2423,261,811,1465,187,771,2231,1774,1154,397,66,3213,170,667,1930,903,2484,1028,814,22,1898,197,150,1599,374,2746,737,2284,2055,3324,841,1118,2485,780,638,520,320,1097,842,1837,717
|
0.021757766555510514,0.8051212350176506,-0.6793500706356256,-0.9942724075500117,0.2756661511961478,-0.3953451725415673,-0.631086208801837,1.7456588522658942,0.021757766555510514,-0.599121814464143,0.050492732938221645,-0.1092398235540067,0.9555364168366788,2.21886249397109,2.4183608115792006,-0.13873418933689516,-0.364590575074656,-0.09454567529886222,1.9814208160018005,2.116716699323345,2.3789579376592007,0.23406828346498643,-0.1535347647507937,-0.45732323785786155,-0.1092398235540067,-0.5832023743822983,0.007339737540638098,-0.06526256357203314,-0.5514878660885424,-0.3953451725415673,2.457521700066298,-0.06526256357203314,0.8556644142476869,-0.16837117607596028,3.0535407471601967,-0.27324496497470774,0.3443787137519083,-0.1535347647507937,-0.05067325033674048,-0.41078076891872717,1.7674589112604508,-0.2581525139593801,-0.9942724075500117,-0.12396926881478841,-0.37994850970962596,-0.3953451725415673,-0.3035420687482125,2.157772335864085,0.1500207496396212,-0.41078076891872717,-0.5514878660885424,-1.0455292059601446,-0.1535347647507937,-0.19815223757022424,1.1144929997983144,-0.2581525139593801,0.007339737540638098,1.0538338490539432,1.281273760705501,0.7669425203474032,1.6132522522142752,1.3977418285889271,0.3443787137519083,-0.3339900772103585,-0.13873418933689516,-0.42625550585234623,0.9925796692463879,-0.45732323785786155,0.5724477159799228,-0.2883747518392183,0.9307180881219075,0.007339737540638098,0.2756661511961478,-0.1092398235540067,0.3716510518956005,0.8304441394676204,-0.44176959203476396,-0.4729166554316845,-0.06526256357203314,1.6132522522142752,0.22013973023415834,-0.42625550585234623,-0.4885500586033537,1.3397781272483118,0.2618313464396684,0.6379588946017836,1.939203453754038,-0.1832436057353802,0.3443787137519083,0.2756661511961478,0.7541640070071953,-0.647131625751063,0.9058005368829619,0.39880353572925303,-1.2906578721061541,-0.7934797786581159,2.4477539937687958,2.3789579376592007,2.706377290804834,0.6639708590611185,0.8556644142476869,0.9307180881219075,0.22013973023415834,0.5328060821965044,-0.27324496497470774,0.31698540656083257,-0.31874711143957013,-0.24309720612430855,1.0902999671477054,1.3630278999226435,-0.5042236629761834,1.7674589112604508,-0.7443040905812541,-0.27324496497470774,-0.12396926881478841,1.3397781272483118,-0.5199376859291878,2.21886249397109,0.021757766555510514,0.9058005368829619,1.7018315064972644,0.35802993391519033,3.918017746429074,1.6687599872367989,0.1641085471368729,-0.12396926881478841,-0.631086208801837,1.991931331193204,-0.45732323785786155,-0.1092398235540067,-0.007112210270966405,-0.7443040905812541,-0.3339900772103585,0.23406828346498643,1.5572509969346298,1.8000185178422223,1.8000185178422223,2.428173597886573,0.2618313464396684,0.4795527769199012,-0.007112210270966405,-1.062711887611437,-0.760651747905037,0.1500207496396212,0.021757766555510514,0.6509785063189131,0.23406828346498643,0.22013973023415834,0.5987352995655117,-0.021598244629604746,0.6898742644114918,2.2289873418727852,0.45275332185277023,2.437971309123152,-0.5199376859291878,1.500746929971123,0.5195356321277029,-0.007112210270966405,1.7456588522658942,0.5724477159799228,-0.41078076891872717,-0.1832436057353802,0.20617963072146406,1.1506078804869229,2.554385400886273,-1.2906578721061541,1.8216320518149403,0.6898742644114918,-0.2581525139593801,0.4123351763696069,-0.5673244671099098,0.3032430368863615,0.5195356321277029,3.1942884268912617,-0.24309720612430855,1.7128169189107314,1.9286049804157963,-0.09454567529886222,1.1984389259522672,-0.728000339684901,0.6118374126406803,-0.44176959203476396,-0.31874711143957013,-1.75491299162932,0.4795527769199012,0.23406828346498643,-0.5673244671099098,0.5592619976723756,0.7285278893546684,0.8933042921551931,1.30474106378976,0.2479654395213026,0.4795527769199012,-0.21309725685462735,0.6379588946017836
| 3,376
|
Golgi organization
| 24
| 65
| 2.931018
| 0.003379
|
P61019,Q9Y3A6,Q8NHH9,Q9UID3,Q9P2W9,Q9H6U6,Q13190,Q7Z3D4,Q9H9E3,Q9BSR8,Q9Y3B3,Q9Y6Y8,P49257,Q15363,Q9H4A6,Q96GC9,O15260,P49755,O15027,Q14999,Q9BVK6,Q53FT3,O43752,Q9UL15
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
767,520,134,150,22,811,304,180,187,703,320,717,331,73,74,78,79,610,486,616,743,498,116,374
|
2164,1394,1601,486,79,1662,116,2287,1605,1533,1518,2175,2006,2208,2447,1704,1430,331,610,965,2295,767,1059,1615,938,2329,1540,2246,304,1760,1060,616,73,498,2047,2386,180,2765,1948,2421,1649,134,2306,1460,2085,78,1074,840,3098,2794,703,1114,743,74,811,1465,187,1028,22,150,374,3324,520,320,717
|
-0.3953451725415673,0.021757766555510514,-0.1092398235540067,0.9555364168366788,2.4183608115792006,-0.13873418933689516,2.116716699323345,-0.45732323785786155,-0.1092398235540067,-0.06526256357203314,-0.05067325033674048,-0.3953451725415673,-0.3035420687482125,-0.41078076891872717,-0.5514878660885424,-0.1535347647507937,0.007339737540638098,1.281273760705501,0.7669425203474032,0.3443787137519083,-0.45732323785786155,0.5724477159799228,0.2756661511961478,-0.1092398235540067,0.3716510518956005,-0.4729166554316845,-0.06526256357203314,-0.42625550585234623,1.3397781272483118,-0.1832436057353802,0.2756661511961478,0.7541640070071953,2.4477539937687958,0.9307180881219075,-0.31874711143957013,-0.5042236629761834,1.7674589112604508,-0.7443040905812541,-0.27324496497470774,-0.5199376859291878,-0.12396926881478841,1.991931331193204,-0.45732323785786155,-0.007112210270966405,-0.3339900772103585,2.428173597886573,0.2618313464396684,0.4795527769199012,-1.062711887611437,-0.760651747905037,0.6509785063189131,0.23406828346498643,0.5987352995655117,2.437971309123152,0.5195356321277029,-0.007112210270966405,1.7456588522658942,0.3032430368863615,3.1942884268912617,1.9286049804157963,1.1984389259522672,-1.75491299162932,0.8933042921551931,1.30474106378976,0.6379588946017836
| 3,376
|
Delusions
| 7
| 17
| 2.927871
| 0.003413
|
P21964,Q96RL7,O43681,Q9NZJ7,Q9UJS0,P04062,P07602
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
159,96,137,173,437,118,469
|
2674,137,118,469,2033,159,1211,1704,514,1758,2078,1651,96,1466,173,1867,437
|
-0.6955235731118161,1.9814208160018005,2.1064111698932244,0.9925796692463879,-0.31874711143957013,1.8646386144308038,0.1500207496396212,-0.1535347647507937,0.8933042921551931,-0.1832436057353802,-0.3339900772103585,-0.12396926881478841,2.2693262981715874,-0.007112210270966405,1.8000185178422223,-0.22807885031082178,1.0538338490539432
| 3,376
|
Hyperlipidemia
| 10
| 30
| 2.920531
| 0.003494
|
P28070,O75844,P49257,P23786,O75431,P31751,P50416,P22830,O95470,P50402
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
353,71,331,265,240,113,307,376,315,220
|
2123,1450,240,71,315,1698,785,1427,376,265,353,1633,113,1878,3240,331,220,307,2868,2014,2214,1820,970,2455,1222,1764,900,1137,437,1421
|
-0.364590575074656,-0.007112210270966405,1.5572509969346298,2.457521700066298,1.30474106378976,-0.1535347647507937,0.5460481617509392,0.007339737540638098,1.1865154018947937,1.466599174519213,1.2340738196350072,-0.12396926881478841,2.157772335864085,-0.24309720612430855,-1.362566906250655,1.281273760705501,1.6132522522142752,1.3281208444722734,-0.8264864472557774,-0.3035420687482125,-0.41078076891872717,-0.21309725685462735,0.3443787137519083,-0.5514878660885424,0.1500207496396212,-0.1832436057353802,0.4123351763696069,0.22013973023415834,1.0538338490539432,0.021757766555510514
| 3,376
|
Phospholipid metabolism
| 8
| 17
| 2.918594
| 0.003516
|
O14735,Q96N66,Q8NF37,Q9UG56,P48651,Q9C0D9,Q9NPH0,Q9HCL2
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
448,225,332,528,141,239,24,27
|
448,897,141,1621,332,1763,663,1480,225,986,810,239,27,24,1203,1553,528
|
1.0294042647856594,0.4123351763696069,1.970892831816529,-0.1092398235540067,1.281273760705501,-0.1832436057353802,0.6898742644114918,-0.021598244629604746,1.602091776312444,0.3306972515746962,0.5195356321277029,1.5684911717900816,3.097855519585872,3.141867551624668,0.1641085471368729,-0.06526256357203314,0.8807829276640542
| 3,376
|
Retrograde transport endosome to golgi
| 14
| 38
| 2.916417
| 0.003541
|
Q8NBN3,Q9Y5X3,Q15836,P49257,O60499,Q13190,O15260,P53367,O75503,O60749,O43752,Q9UID3,O95249,Q4J6C6
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
32,392,559,331,11,304,79,686,241,623,116,150,88,634
|
79,1602,116,1079,1695,11,623,1841,241,88,2035,2447,331,2072,1613,686,2596,304,1382,969,559,634,1198,1824,1596,2421,32,1460,1953,929,743,1578,2511,1256,150,3312,1295,392
|
2.4183608115792006,-0.1092398235540067,2.116716699323345,0.2479654395213026,-0.1535347647507937,3.450194354038298,0.7413591680028151,-0.22807885031082178,1.5572509969346298,2.32935923806442,-0.31874711143957013,-0.5514878660885424,1.281273760705501,-0.3339900772103585,-0.1092398235540067,0.6639708590611185,-0.647131625751063,1.3397781272483118,0.03614204326984603,0.3443787137519083,0.8304441394676204,0.7285278893546684,0.1641085471368729,-0.21309725685462735,-0.09454567529886222,-0.5199376859291878,3.0357290886065282,-0.007112210270966405,-0.27324496497470774,0.3852422065417807,0.5987352995655117,-0.07988664715431047,-0.5832023743822983,0.12174807413919582,1.9286049804157963,-1.678171482939842,0.09334491384878002,1.1625999707615722
| 3,376
|
Cholesterol binding
| 6
| 13
| 2.915808
| 0.003548
|
Q14849,P21796,P45880,P30536,Q14108,P35610
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
98,41,44,334,147,501
|
506,1373,2353,2207,41,1429,334,501,44,1455,147,98,2229
|
0.9058005368829619,0.03614204326984603,-0.4885500586033537,-0.41078076891872717,2.8548455407684523,0.007339737540638098,1.2695070730093605,0.9182717672838793,2.7903132643602064,-0.007112210270966405,1.939203453754038,2.249188800352927,-0.41078076891872717
| 3,376
|
Tetrapyrrole metabolic process
| 9
| 19
| 2.915735
| 0.003549
|
O00264,P30519,Q9P0S9,P09601,Q96EY8,P30536,P22830,Q99707,O75027
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
198,38,463,9,297,334,376,443,473
|
198,2059,473,2752,2033,9,376,38,334,1211,1501,572,297,443,1689,463,2529,2395,1447
|
1.7018315064972644,-0.3339900772103585,0.9802563479044419,-0.7443040905812541,-0.31874711143957013,3.508477031496731,1.1865154018947937,2.9005459852632884,1.2695070730093605,0.1500207496396212,-0.03611853455253771,0.8177955706609692,1.3630278999226435,1.0416310057595912,-0.13873418933689516,1.017153527787551,-0.599121814464143,-0.5042236629761834,0.007339737540638098
| 3,376
|
Calcium signaling pathway
| 8
| 18
| 2.905785
| 0.003663
|
P12235,Q9Y277,P21796,P45880,P16615,P12236,Q13555,Q08209
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
97,136,41,44,178,375,254,379
|
609,1785,97,375,178,1910,2005,3139,845,41,44,982,379,2012,254,407,1188,136
|
0.7669425203474032,-0.19815223757022424,2.2592655177971985,1.1865154018947937,1.7674589112604508,-0.2581525139593801,-0.3035420687482125,-1.1493665932391064,0.46616755845459307,2.8548455407684523,2.7903132643602064,0.3306972515746962,1.1745691139378525,-0.3035420687482125,1.5120884232445022,1.126554488303031,0.17816419100440917,1.991931331193204
| 3,376
|
Biliary tract abnormality
| 12
| 29
| 2.904881
| 0.003674
|
P50542,P14174,Q10713,O43933,O95202,P09601,O43681,Q9NZJ7,Q14108,P04062,P07602,Q14739
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
286,481,388,513,358,9,137,173,147,118,469,347
|
137,513,358,2468,1698,118,469,9,481,2848,2432,2685,286,1358,753,388,1162,2834,147,347,585,1683,1047,1236,1026,173,1490,1155,781
|
1.9814208160018005,0.8933042921551931,1.222218044879942,-0.5673244671099098,-0.1535347647507937,2.1064111698932244,0.9925796692463879,3.508477031496731,0.9679086309299181,-0.8099606559026915,-0.535692346636734,-0.6955235731118161,1.3977418285889271,0.050492732938221645,0.5856054418382873,1.1625999707615722,0.19218783473832943,-0.7934797786581159,1.939203453754038,1.245907190269227,0.8051212350176506,-0.13873418933689516,0.28946999971654247,0.13590064389229117,0.3032430368863615,1.8000185178422223,-0.021598244629604746,0.20617963072146406,0.5592619976723756
| 3,376
|
Golgi apparatus
| 58
| 183
| 2.90305
| 0.003695
|
Q8NC54,P67812,P09601,Q9H3P7,Q9HD26,Q9UG56,O60499,O00461,P80303,P16278,Q5VZ89,Q9UID3,Q8N4Q0,Q8IYS2,Q8NBN3,P50542,Q8NCH0,Q9NPR9,A1L0T0,Q96RQ1,Q9HC07,P50897,Q9NWM8,Q13190,Q5VW38,Q93050,Q6ZRP7,P98194,O15258,Q96K37,Q9H4A6,P05067,Q92520,Q8WVQ1,Q99576,O15260,Q8IXU6,O43760,Q99640,Q9H0U4,Q9NTJ5,Q02818,P04439,Q9NX62,Q9H2V7,O95070,P49755,Q9HB40,O15027,Q8TDW0,Q99523,Q9HD45,O43752,Q8TD16,Q9BRK5,O60637,P53365,Q8IZA0
|
Localization
|
Protein Atlas Subcellular
|
protein_atlas_subcellular_location_all
|
6,7,9,396,526,528,11,146,19,273,532,150,283,542,32,286,34,35,418,168,43,47,176,304,52,55,442,568,565,586,74,204,77,205,207,79,597,84,212,471,472,344,468,219,92,99,610,227,486,618,636,114,116,372,119,121,507,253
|
418,3003,2286,921,146,1811,1601,486,856,1055,565,79,1661,1189,3245,2124,3238,116,84,1840,11,121,2287,3150,1605,3163,1782,1534,1080,99,1057,468,204,3362,9,2127,1355,273,2357,2035,2147,2591,2407,3165,2293,949,1038,632,2265,2447,1915,2149,1916,610,286,965,1705,47,2449,1755,507,686,2471,1635,858,2810,7,19,938,568,2271,344,2812,1540,1215,1197,304,2076,2215,1060,2274,2691,910,1824,2047,1856,52,532,1709,1890,1796,1108,797,1339,1458,1021,2335,442,3124,2456,1644,1407,2692,1645,1109,2421,3192,597,1545,542,253,1949,283,1826,1220,32,6,34,1316,372,3031,618,205,77,1460,1576,55,690,1201,1684,972,2048,770,1136,1074,586,840,2941,168,1112,636,207,2373,212,2794,3176,119,691,703,973,2280,2090,2116,471,92,396,2117,74,1465,1077,227,43,526,114,35,1990,1580,472,176,219,1389,528,1419,150,1420,1009,3312,1717,2313,2199,2885,842,1747
|
1.0781682329246185,-0.9603410571851295,-0.45732323785786155,0.3852422065417807,1.939203453754038,-0.21309725685462735,-0.1092398235540067,0.9555364168366788,0.45275332185277023,0.2756661511961478,0.8177955706609692,2.4183608115792006,-0.13873418933689516,0.1641085471368729,-1.380679358108941,-0.364590575074656,-1.362566906250655,2.116716699323345,2.3789579376592007,-0.22807885031082178,3.450194354038298,2.0960888788447267,-0.45732323785786155,-1.1668478915554994,-0.1092398235540067,-1.1843800211435078,-0.19815223757022424,-0.06526256357203314,0.2479654395213026,2.2390960928105765,0.2756661511961478,0.9925796692463879,1.6798031111121596,-2.7625821237366743,3.508477031496731,-0.364590575074656,0.050492732938221645,1.4437304908127628,-0.4885500586033537,-0.31874711143957013,-0.37994850970962596,-0.647131625751063,-0.5199376859291878,-1.1843800211435078,-0.45732323785786155,0.35802993391519033,0.28946999971654247,0.7285278893546684,-0.44176959203476396,-0.5514878660885424,-0.2581525139593801,-0.37994850970962596,-0.2581525139593801,0.7669425203474032,1.3977418285889271,0.3443787137519083,-0.1535347647507937,2.743817956942605,-0.5514878660885424,-0.1832436057353802,0.9058005368829619,0.6639708590611185,-0.5673244671099098,-0.12396926881478841,0.45275332185277023,-0.7770435603241972,3.6071872129131113,3.3064270469258985,0.3716510518956005,0.8177955706609692,-0.44176959203476396,1.245907190269227,-0.7770435603241972,-0.06526256357203314,0.1500207496396212,0.1641085471368729,1.3397781272483118,-0.3339900772103585,-0.41078076891872717,0.2756661511961478,-0.44176959203476396,-0.6955235731118161,0.39880353572925303,-0.21309725685462735,-0.31874711143957013,-0.22807885031082178,2.6875745657573895,0.8682363372946176,-0.1535347647507937,-0.24309720612430855,-0.19815223757022424,0.23406828346498643,0.5328060821965044,0.06480999958601061,-0.007112210270966405,0.3032430368863615,-0.4729166554316845,1.0416310057595912,-1.1145552610735343,-0.5514878660885424,-0.12396926881478841,0.021757766555510514,-0.6955235731118161,-0.12396926881478841,0.23406828346498643,-0.5199376859291878,-1.237284521255809,0.7924210222267182,-0.06526256357203314,0.8556644142476869,1.5234094998830219,-0.27324496497470774,1.4092706071160868,-0.21309725685462735,0.1500207496396212,3.0357290886065282,3.647877425892824,2.927810977237293,0.07909400602166337,1.1984389259522672,-0.9772829358324227,0.7541640070071953,1.6798031111121596,2.428173597886573,-0.007112210270966405,-0.07988664715431047,2.6781524570436264,0.6639708590611185,0.1641085471368729,-0.13873418933689516,0.3443787137519083,-0.31874711143957013,0.5724477159799228,0.22013973023415834,0.2618313464396684,0.8051212350176506,0.4795527769199012,-0.8763358915188677,1.8216320518149403,0.23406828346498643,0.7285278893546684,1.6798031111121596,-0.4885500586033537,1.6576974846458383,-0.760651747905037,-1.20196329291841,2.1064111698932244,0.6639708590611185,0.6509785063189131,0.3443787137519083,-0.44176959203476396,-0.3339900772103585,-0.34927116493347793,0.9925796692463879,2.2793711942368797,1.1506078804869229,-0.34927116493347793,2.437971309123152,-0.007112210270966405,0.2618313464396684,1.602091776312444,2.8088173906325995,0.8807829276640542,2.157772335864085,2.927810977237293,-0.2883747518392183,-0.07988664715431047,0.9925796692463879,1.789183956579087,1.6243929881344374,0.03614204326984603,0.8807829276640542,0.021757766555510514,1.9286049804157963,0.021757766555510514,0.31698540656083257,-1.678171482939842,-0.1535347647507937,-0.45732323785786155,-0.3953451725415673,-0.8264864472557774,0.4795527769199012,-0.16837117607596028
| 3,376
|
Huntingtons disease
| 17
| 80
| 2.89691
| 0.003769
|
P12235,Q9UDW1,P13073,P14406,Q9Y277,P21796,P45880,P21912,P12236,O14949,O95168,O43676,Q9Y6M9,P00846,P20674,P00403,O96000
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
97,36,100,8,136,41,44,268,375,18,343,25,282,28,317,95,30
|
1903,1559,1243,18,2315,763,25,1603,1812,566,1324,1397,3020,343,1561,1326,2678,30,95,28,3335,2067,609,751,907,2288,2430,1909,97,375,100,8,2289,1175,2805,1143,3153,317,41,268,879,408,2948,3023,2240,3006,1264,2322,1209,981,2434,1704,44,2408,3271,3129,538,2410,2594,1435,2436,2010,2733,1919,2596,2012,1019,458,969,2837,2762,1822,1892,2769,2461,36,1490,2904,136,282
|
-0.2581525139593801,-0.07988664715431047,0.12174807413919582,3.3235076545102,-0.4729166554316845,0.5724477159799228,3.106682006127666,-0.1092398235540067,-0.21309725685462735,0.8177955706609692,0.06480999958601061,0.021757766555510514,-0.9772829358324227,1.245907190269227,-0.07988664715431047,0.06480999958601061,-0.6955235731118161,3.0446410783605184,2.2693262981715874,3.0624281306689123,-1.8916308685435954,-0.3339900772103585,0.7669425203474032,0.5856054418382873,0.39880353572925303,-0.45732323785786155,-0.535692346636734,-0.2581525139593801,2.2592655177971985,1.1865154018947937,2.2390960928105765,3.549788972453769,-0.45732323785786155,0.17816419100440917,-0.7770435603241972,0.20617963072146406,-1.1668478915554994,1.30474106378976,2.8548455407684523,1.4551752366331643,0.42583726441943925,1.1144929997983144,-0.8930439362355179,-0.9772829358324227,-0.42625550585234623,-0.9603410571851295,0.1075628834780911,-0.4729166554316845,0.1500207496396212,0.3306972515746962,-0.535692346636734,-0.1535347647507937,2.7903132643602064,-0.5199376859291878,-1.4720700709953676,-1.1319358181488326,0.8556644142476869,-0.5199376859291878,-0.647131625751063,0.007339737540638098,-0.535692346636734,-0.3035420687482125,-0.728000339684901,-0.2581525139593801,-0.647131625751063,-0.3035420687482125,0.3032430368863615,1.017153527787551,0.3443787137519083,-0.7934797786581159,-0.7443040905812541,-0.21309725685462735,-0.24309720612430855,-0.7443040905812541,-0.5514878660885424,2.9187354965517494,-0.021598244629604746,-0.8430574101429883,1.991931331193204,1.420778256383682
| 3,376
|
Sphingolipid metabolism
| 8
| 10
| 2.896438
| 0.003774
|
Q06136,Q13510,Q16739,Q9NZ01,P04062,P07602,P17900,O95470
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
103,175,51,278,118,469,500,315
|
521,1781,315,118,469,500,103,175,51,278
|
0.8807829276640542,-0.19815223757022424,1.30474106378976,2.1064111698932244,0.9925796692463879,0.9182717672838793,2.2289873418727852,1.789183956579087,2.706377290804834,1.4322648574279548
| 3,376
|
Organophosphate ester transmembrane transporter activity
| 6
| 13
| 2.873757
| 0.004056
|
P12235,Q9BSK2,Q86VD7,Q6KCM7,Q9H2D1,Q8TB61
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
97,3,72,76,15,112
|
1189,727,609,97,375,3078,76,679,72,112,3,15,193
|
0.1641085471368729,0.6118374126406803,0.7669425203474032,2.2592655177971985,1.1865154018947937,-1.0455292059601446,2.428173597886573,0.6769360722247575,2.457521700066298,2.1679949059006707,3.8868120422021692,3.349044243996922,1.72378323442192
| 3,376
|
Nucleotide transmembrane transporter activity
| 6
| 13
| 2.873757
| 0.004056
|
P12235,Q9BSK2,Q86VD7,Q6KCM7,Q9H2D1,Q8TB61
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
97,3,72,76,15,112
|
1189,727,609,97,375,3078,76,679,72,112,3,15,193
|
0.1641085471368729,0.6118374126406803,0.7669425203474032,2.2592655177971985,1.1865154018947937,-1.0455292059601446,2.428173597886573,0.6769360722247575,2.457521700066298,2.1679949059006707,3.8868120422021692,3.349044243996922,1.72378323442192
| 3,376
|
secondary carrier transporter
| 9
| 14
| 2.872133
| 0.004077
|
Q9BQT8,Q96K37,O95202,O75746,Q8TB61,Q9UJS0,Q02978,Q8WWI5,Q9UBX3
|
Functions
|
Panther Protein class
|
panther_protein_class
|
475,586,358,489,112,437,594,573,59
|
489,358,1196,594,2253,112,573,586,475,1171,59,437,1257,726
|
0.9431396034941706,1.222218044879942,0.1641085471368729,0.7924210222267182,-0.42625550585234623,2.1679949059006707,0.8177955706609692,0.8051212350176506,0.9802563479044419,0.19218783473832943,2.6498026320516255,1.0538338490539432,0.12174807413919582,0.6249119037114952
| 3,376
|
Insertion of tail anchored proteins into the endoplasmic reticulum membrane
| 8
| 12
| 2.871426
| 0.004086
|
Q7L5D6,P09601,O43681,P05067,Q13190,P51648,P46379,P50402
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
296,9,137,204,304,80,409,220
|
137,1098,204,9,409,431,220,80,2968,304,296,2484
|
1.9814208160018005,0.23406828346498643,1.6798031111121596,3.508477031496731,1.1144929997983144,1.0538338490539432,1.6132522522142752,2.4183608115792006,-0.9097982049966251,1.3397781272483118,1.3630278999226435,-0.5673244671099098
| 3,376
|
Endoplasmic reticulum tubular network organization
| 7
| 12
| 2.870215
| 0.004102
|
Q9NQC3,Q9H6H4,Q8NHH9,P61026,P57088,O95197,Q6NUK4
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
66,261,134,495,470,29,415
|
29,470,495,508,909,415,134,1487,864,261,1774,66
|
3.0535407471601967,0.9925796692463879,0.9307180881219075,0.9058005368829619,0.39880353572925303,1.0902999671477054,1.991931331193204,-0.021598244629604746,0.45275332185277023,1.500746929971123,-0.1832436057353802,2.554385400886273
| 3,376
|
Macromolecule transmembrane transporter activity
| 7
| 12
| 2.856671
| 0.004281
|
O60830,Q9NS69,Q07820,Q99595,O96008,Q15388,O14925
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
0,2,323,4,523,242,156
|
156,0,1325,523,610,966,1437,323,242,4,2,855
|
1.8860326867293702,3.918017746429074,0.06480999958601061,0.8807829276640542,0.7669425203474032,0.3443787137519083,0.007339737540638098,1.2930183954698358,1.5572509969346298,3.8081377581322435,3.918017746429074,0.46616755845459307
| 3,376
|
Sterol binding
| 6
| 16
| 2.8555
| 0.004297
|
Q14849,P21796,P45880,P30536,Q14108,P35610
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
98,41,44,334,147,501
|
506,1373,2353,2207,41,2147,1429,334,501,44,1455,147,98,1112,2090,2229
|
0.9058005368829619,0.03614204326984603,-0.4885500586033537,-0.41078076891872717,2.8548455407684523,-0.37994850970962596,0.007339737540638098,1.2695070730093605,0.9182717672838793,2.7903132643602064,-0.007112210270966405,1.939203453754038,2.249188800352927,0.23406828346498643,-0.3339900772103585,-0.41078076891872717
| 3,376
|
oxidase
| 6
| 13
| 2.853327
| 0.004326
|
P13073,P14406,Q6ZRP7,O75880,P20674,Q15800
|
Functions
|
Panther Protein class
|
panther_protein_class
|
100,8,442,188,317,126
|
1243,602,1869,188,1909,100,8,1175,317,1211,126,442,1648
|
0.12174807413919582,0.779694821256333,-0.24309720612430855,1.7347305225090166,-0.2581525139593801,2.2390960928105765,3.549788972453769,0.17816419100440917,1.30474106378976,0.1500207496396212,2.0650208618258294,1.0416310057595912,-0.12396926881478841
| 3,376
|
Abnormality of head blood vessel
| 12
| 24
| 2.852856
| 0.004333
|
P21964,P06865,P10619,P03886,Q9NZJ7,P48651,Q9C0D9,Q13510,P16278,Q9Y4P3,P07602,P00846
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
159,386,132,68,173,141,239,175,273,279,469,28
|
1660,2123,28,68,386,469,2680,132,2497,273,500,159,949,141,2326,3111,175,697,2525,760,239,173,3117,279
|
-0.13873418933689516,-0.364590575074656,3.0624281306689123,2.525480253725994,1.1625999707615722,0.9925796692463879,-0.6955235731118161,2.012900196950257,-0.5832023743822983,1.4437304908127628,0.9182717672838793,1.8646386144308038,0.35802993391519033,1.970892831816529,-0.4729166554316845,-1.0972246196014959,1.789183956579087,0.6509785063189131,-0.599121814464143,0.5856054418382873,1.5684911717900816,1.8000185178422223,-1.0972246196014959,1.4322648574279548
| 3,376
|
Optic neuropathy
| 7
| 23
| 2.851473
| 0.004352
|
P03886,Q9NPL8,Q9P0J0,O43676,P00846,Q86Y39,O96000
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
68,232,93,25,28,62,30
|
25,1812,566,1324,30,28,68,3153,3006,1969,3129,1435,62,2219,2191,1926,562,2089,232,1254,2745,93,282
|
3.106682006127666,-0.21309725685462735,0.8177955706609692,0.06480999958601061,3.0446410783605184,3.0624281306689123,2.525480253725994,-1.1668478915554994,-0.9603410571851295,-0.2883747518392183,-1.1319358181488326,0.007339737540638098,2.62132664953133,-0.41078076891872717,-0.3953451725415673,-0.2581525139593801,0.8304441394676204,-0.3339900772103585,1.5909114869453034,0.12174807413919582,-0.728000339684901,2.2793711942368797,1.420778256383682
| 3,376
|
Steroid biosynthetic process
| 15
| 46
| 2.849574
| 0.004378
|
P00387,Q16850,Q14849,Q9H2C2,Q9H3P7,P11413,P37268,P16435,Q13510,P30536,P04035,Q15392,Q14534,Q14739,Q15800
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
321,65,98,104,396,393,238,456,175,334,251,87,153,347,126
|
578,1373,2353,321,251,707,393,802,2623,456,1013,2147,1429,2912,1245,334,238,1913,1194,1477,2995,3219,1269,175,3065,153,347,98,2664,87,1311,658,126,65,465,1022,2899,2195,1112,2987,2392,104,396,2347,779,2617
|
0.8051212350176506,0.03614204326984603,-0.4885500586033537,1.2930183954698358,1.5234094998830219,0.6379588946017836,1.1506078804869229,0.5195356321277029,-0.6632195009402341,1.017153527787551,0.3032430368863615,-0.37994850970962596,0.007339737540638098,-0.8596738042439521,0.12174807413919582,1.2695070730093605,1.5684911717900816,-0.2581525139593801,0.1641085471368729,-0.021598244629604746,-0.94344649290514,-1.3085546915454922,0.1075628834780911,1.789183956579087,-1.0283952575793793,1.8967026461556973,1.245907190269227,2.249188800352927,-0.6793500706356256,2.339309921504243,0.07909400602166337,0.6898742644114918,2.0650208618258294,2.554385400886273,1.0048786958028963,0.3032430368863615,-0.8430574101429883,-0.3953451725415673,0.23406828346498643,-0.9265989667676673,-0.5042236629761834,2.2289873418727852,1.1506078804869229,-0.4729166554316845,0.5592619976723756,-0.647131625751063
| 3,376
|
Secondary alcohol metabolic process
| 16
| 41
| 2.847426
| 0.004407
|
P00387,Q16850,Q14849,Q9H2C2,P11413,Q8WTV0,P05067,P16435,P37268,P04035,P04062,P35610,Q15392,Q14534,Q14739,Q15800
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
321,65,98,104,393,300,204,456,238,251,118,501,87,153,347,126
|
506,2316,1373,2865,2353,321,251,118,204,393,802,456,2912,501,238,1913,1194,3140,2008,3025,1477,2995,1455,2571,3219,1269,3065,153,347,98,1336,2664,87,658,126,65,300,3132,104,2347,2232
|
0.9058005368829619,-0.4729166554316845,0.03614204326984603,-0.8264864472557774,-0.4885500586033537,1.2930183954698358,1.5234094998830219,2.1064111698932244,1.6798031111121596,1.1506078804869229,0.5195356321277029,1.017153527787551,-0.8596738042439521,0.9182717672838793,1.5684911717900816,-0.2581525139593801,0.1641085471368729,-1.1493665932391064,-0.3035420687482125,-0.9772829358324227,-0.021598244629604746,-0.94344649290514,-0.007112210270966405,-0.631086208801837,-1.3085546915454922,0.1075628834780911,-1.0283952575793793,1.8967026461556973,1.245907190269227,2.249188800352927,0.06480999958601061,-0.6793500706356256,2.339309921504243,0.6898742644114918,2.0650208618258294,2.554385400886273,1.3514137844149743,-1.1319358181488326,2.2289873418727852,-0.4729166554316845,-0.41078076891872717
| 3,376
|
Establishment of protein localization to mitochondrial membrane
| 10
| 17
| 2.844886
| 0.004443
|
Q9NS69,Q53H12,Q9Y512,O14737,Q9Y5L4,Q9Y5J7,P30419,Q15070,Q9Y5J9,Q9P0J0
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
2,290,417,326,668,429,556,86,157,93
|
2286,326,1325,1701,1785,556,2806,86,290,733,2,93,1155,417,429,157,668
|
-0.45732323785786155,1.281273760705501,0.06480999958601061,-0.1535347647507937,-0.19815223757022424,0.8304441394676204,-0.7770435603241972,2.369069040392317,1.386191839289798,0.6118374126406803,3.918017746429074,2.2793711942368797,0.20617963072146406,1.0902999671477054,1.0660128924007646,1.8860326867293702,0.6898742644114918
| 3,376
|
Intrinsic component of golgi membrane
| 8
| 10
| 2.835247
| 0.004579
|
O95070,Q9Y282,L0R6Q1,Q8TB61,O43505,Q969X5,Q6ZRP7,P98194
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
99,75,333,112,553,311,442,568
|
333,565,553,99,568,1215,442,112,311,75
|
1.2695070730093605,0.8177955706609692,0.8304441394676204,2.2390960928105765,0.8177955706609692,0.1500207496396212,1.0416310057595912,2.1679949059006707,1.3281208444722734,2.437971309123152
| 3,376
|
ER-Golgi transport
| 12
| 51
| 2.835142
| 0.004581
|
O95070,O15027,Q96RQ1,P49257,Q15363,Q9Y282,P49069,Q9P2W9,Q969X5,O95249,O95197,Q9HCU5
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
99,486,168,331,73,75,431,22,311,88,29,350
|
1811,486,1602,1662,3238,2287,1533,1722,99,29,88,1844,1963,2239,2035,1038,1916,431,331,610,673,2471,1635,2326,1502,767,2366,1059,1310,2896,73,1089,2298,796,1108,2386,1798,1220,889,1764,311,168,2050,350,546,1078,22,1554,75,1229,1747
|
-0.21309725685462735,0.9555364168366788,-0.1092398235540067,-0.13873418933689516,-1.362566906250655,-0.45732323785786155,-0.06526256357203314,-0.16837117607596028,2.2390960928105765,3.0535407471601967,2.32935923806442,-0.22807885031082178,-0.2883747518392183,-0.42625550585234623,-0.31874711143957013,0.28946999971654247,-0.2581525139593801,1.0538338490539432,1.281273760705501,0.7669425203474032,0.6769360722247575,-0.5673244671099098,-0.12396926881478841,-0.4729166554316845,-0.03611853455253771,0.5724477159799228,-0.4885500586033537,0.2756661511961478,0.07909400602166337,-0.8430574101429883,2.4477539937687958,0.2479654395213026,-0.45732323785786155,0.5328060821965044,0.23406828346498643,-0.5042236629761834,-0.19815223757022424,0.1500207496396212,0.42583726441943925,-0.1832436057353802,1.3281208444722734,1.8216320518149403,-0.31874711143957013,1.245907190269227,0.8556644142476869,0.2618313464396684,3.1942884268912617,-0.06526256357203314,2.437971309123152,0.1500207496396212,-0.16837117607596028
| 3,376
|
Intrinsic component of mitochondrial outer membrane
| 8
| 14
| 2.832973
| 0.004612
|
Q9BWH2,Q8TB36,O96008,Q15388,P50416,Q9GZY8,P57105,Q8IWA4
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
196,258,523,242,307,373,313,605
|
1325,670,523,307,313,242,2478,605,927,1459,258,196,373,1419
|
0.06480999958601061,0.6769360722247575,0.8807829276640542,1.3281208444722734,1.3164418516370977,1.5572509969346298,-0.5673244671099098,0.779694821256333,0.3852422065417807,-0.007112210270966405,1.500746929971123,1.7128169189107314,1.1984389259522672,0.021757766555510514
| 3,376
|
Regulation of mitochondrion organization
| 15
| 43
| 2.83237
| 0.00462
|
P12235,Q9H3K2,Q96A26,O14737,P21796,Q9H4A6,Q9UG56,O60313,P30536,P30419,Q9GZY8,Q9Y6C9,O43464,O00165,Q99536
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
97,453,40,326,41,74,528,236,334,556,373,120,530,504,545
|
504,1054,326,530,236,1843,1698,1699,2067,609,2709,97,2682,41,2930,556,334,1913,1704,2685,1159,786,711,2215,1948,927,1459,1001,1073,40,2278,929,2942,545,373,453,74,1226,1628,833,528,2395,120
|
0.9058005368829619,0.2756661511961478,1.281273760705501,0.8682363372946176,1.5797113102117606,-0.22807885031082178,-0.1535347647507937,-0.1535347647507937,-0.3339900772103585,0.7669425203474032,-0.7117402486747223,2.2592655177971985,-0.6955235731118161,2.8548455407684523,-0.8763358915188677,0.8304441394676204,1.2695070730093605,-0.2581525139593801,-0.1535347647507937,-0.6955235731118161,0.19218783473832943,0.5460481617509392,0.6379588946017836,-0.41078076891872717,-0.27324496497470774,0.3852422065417807,-0.007112210270966405,0.31698540656083257,0.2618313464396684,2.8640116891864733,-0.44176959203476396,0.3852422065417807,-0.8763358915188677,0.8556644142476869,1.1984389259522672,1.0294042647856594,2.437971309123152,0.1500207496396212,-0.1092398235540067,0.49290910856241765,0.8807829276640542,-0.5042236629761834,2.1064111698932244
| 3,376
|
calmodulin-related
| 6
| 14
| 2.827894
| 0.004686
|
Q9BPX6,Q14257,O43852,P80303,Q02818,Q9BRK5
|
Functions
|
Panther Protein class
|
panther_protein_class
|
512,64,302,19,344,119
|
302,1785,2129,846,820,1307,19,344,64,1593,533,1741,512,119
|
1.3397781272483118,-0.19815223757022424,-0.364590575074656,0.46616755845459307,0.5062366837929436,0.07909400602166337,3.3064270469258985,1.245907190269227,2.592723326528482,-0.09454567529886222,0.8682363372946176,-0.16837117607596028,0.9058005368829619,2.1064111698932244
| 3,376
|
Abnormality of corneal stroma
| 6
| 12
| 2.826411
| 0.004707
|
P50542,P10619,O43933,Q13510,P16278,P04062
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
286,132,513,175,273,118
|
553,513,118,132,273,1965,1452,286,1564,175,1313,1053
|
0.8304441394676204,0.8933042921551931,2.1064111698932244,2.012900196950257,1.4437304908127628,-0.2883747518392183,-0.007112210270966405,1.3977418285889271,-0.07988664715431047,1.789183956579087,0.07909400602166337,0.28946999971654247
| 3,376
|
Incoordination
| 29
| 72
| 2.815499
| 0.00487
|
Q10713,O43681,P21912,Q9Y619,Q9NVV4,P00846,Q9NR77,Q01105,O95140,P53007,Q9NZJ7,Q13510,Q99707,O14773,Q13501,Q9UJX6,Q9Y5P6,P07602,O43819,P12235,Q6DKK2,Q05086,Q8TC12,O75503,P04062,O00165,Q9UBB4,P35670,Q15067
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
388,137,268,272,536,28,31,294,670,425,173,175,443,61,711,725,341,469,602,97,224,740,628,241,118,504,384,632,255
|
504,3284,2674,61,2123,1694,137,602,2491,2144,241,991,670,827,28,118,2206,469,3223,97,2003,268,1014,2322,1454,632,1634,794,1704,1016,2565,425,753,1852,3079,1818,2180,294,2919,740,2074,388,711,175,1820,2415,255,2836,1709,224,3322,1710,2875,1948,628,2793,929,1483,443,2987,1236,2744,1957,31,536,173,384,1899,1188,725,341,272
|
0.9058005368829619,-1.5648744215576544,-0.6955235731118161,2.62132664953133,-0.364590575074656,-0.1535347647507937,1.9814208160018005,0.779694821256333,-0.5832023743822983,-0.37994850970962596,1.5572509969346298,0.31698540656083257,0.6769360722247575,0.49290910856241765,3.0624281306689123,2.1064111698932244,-0.41078076891872717,0.9925796692463879,-1.3265049130332804,2.2592655177971985,-0.3035420687482125,1.4551752366331643,0.3032430368863615,-0.4729166554316845,-0.007112210270966405,0.7285278893546684,-0.12396926881478841,0.5328060821965044,-0.1535347647507937,0.3032430368863615,-0.631086208801837,1.0660128924007646,0.5856054418382873,-0.22807885031082178,-1.0455292059601446,-0.21309725685462735,-0.3953451725415673,1.3630278999226435,-0.8596738042439521,0.5987352995655117,-0.3339900772103585,1.1625999707615722,0.6379588946017836,1.789183956579087,-0.21309725685462735,-0.5199376859291878,1.5120884232445022,-0.7934797786581159,-0.1535347647507937,1.602091776312444,-1.75491299162932,-0.1535347647507937,-0.8264864472557774,-0.27324496497470774,0.7413591680028151,-0.760651747905037,0.3852422065417807,-0.021598244629604746,1.0416310057595912,-0.9265989667676673,0.13590064389229117,-0.728000339684901,-0.27324496497470774,3.0446410783605184,0.8682363372946176,1.8000185178422223,1.1745691139378525,-0.24309720612430855,0.17816419100440917,0.6249119037114952,1.2577182453742726,1.4551752366331643
| 3,376
|
O acyltransferase activity
| 8
| 14
| 2.814404
| 0.004887
|
Q96N66,Q8NF37,P23786,Q92604,P50416,P35610,O15228,Q9HCL2
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
225,332,265,663,307,501,529,27
|
529,265,2625,501,307,1621,689,332,663,225,986,27,1553,1468
|
0.8682363372946176,1.466599174519213,-0.6632195009402341,0.9182717672838793,1.3281208444722734,-0.1092398235540067,0.6639708590611185,1.281273760705501,0.6898742644114918,1.602091776312444,0.3306972515746962,3.097855519585872,-0.06526256357203314,-0.007112210270966405
| 3,376
|
Progressive gait ataxia
| 8
| 13
| 2.813654
| 0.004898
|
O43681,Q9NW15,Q9NZJ7,Q05086,Q9NVV4,P07602,P00846,O14773
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
137,234,173,740,536,469,28,61
|
61,1694,137,28,469,2003,753,1564,740,1483,536,234,173
|
2.62132664953133,-0.1535347647507937,1.9814208160018005,3.0624281306689123,0.9925796692463879,-0.3035420687482125,0.5856054418382873,-0.07988664715431047,0.5987352995655117,-0.021598244629604746,0.8682363372946176,1.5909114869453034,1.8000185178422223
| 3,376
|
Memory impairment
| 10
| 39
| 2.812222
| 0.00492
|
P03886,P49770,O43681,Q9NZJ7,P05067,Q9UJS0,P07602,Q9NZ08,P00403,Q9UNE7
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
68,514,137,173,204,437,469,314,95,319
|
137,523,95,68,204,469,2033,2652,1454,1704,1331,1126,514,1755,753,1564,1852,1539,2573,1920,1758,711,2078,2301,3143,1575,1927,1483,1466,314,173,1898,1867,437,319,1118,1718,1447,1296
|
1.9814208160018005,0.8807829276640542,2.2693262981715874,2.525480253725994,1.6798031111121596,0.9925796692463879,-0.31874711143957013,-0.6793500706356256,-0.007112210270966405,-0.1535347647507937,0.06480999958601061,0.22013973023415834,0.8933042921551931,-0.1832436057353802,0.5856054418382873,-0.07988664715431047,-0.22807885031082178,-0.06526256357203314,-0.631086208801837,-0.2581525139593801,-0.1832436057353802,0.6379588946017836,-0.3339900772103585,-0.45732323785786155,-1.1493665932391064,-0.07988664715431047,-0.2581525139593801,-0.021598244629604746,-0.007112210270966405,1.3164418516370977,1.8000185178422223,-0.24309720612430855,-0.22807885031082178,1.0538338490539432,1.30474106378976,0.23406828346498643,-0.1535347647507937,0.007339737540638098,0.09334491384878002
| 3,376
|
Mitochondrial nucleotide transporter subfamily
| 7
| 11
| 2.812103
| 0.004922
|
P12235,Q9HC21,Q9BSK2,Q86VD7,Q6KCM7,Q9H2D1,Q70HW3
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
97,193,3,72,76,15,248
|
727,609,97,375,76,679,248,72,3,15,193
|
0.6118374126406803,0.7669425203474032,2.2592655177971985,1.1865154018947937,2.428173597886573,0.6769360722247575,1.5347102368011099,2.457521700066298,3.8868120422021692,3.349044243996922,1.72378323442192
| 3,376
|
Protein transmembrane transporter activity
| 7
| 11
| 2.80707
| 0.004999
|
O60830,Q9NS69,Q07820,Q99595,O96008,Q15388,O14925
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
0,2,323,4,523,242,156
|
156,0,1325,523,610,1437,323,242,4,2,855
|
1.8860326867293702,3.918017746429074,0.06480999958601061,0.8807829276640542,0.7669425203474032,0.007339737540638098,1.2930183954698358,1.5572509969346298,3.8081377581322435,3.918017746429074,0.46616755845459307
| 3,376
|
Mental deterioration
| 36
| 109
| 2.800415
| 0.005104
|
P06865,Q10713,O43681,Q9UHD9,P21912,O96008,Q14108,P16278,O43464,P00846,P21964,Q9NZJ7,P50897,Q13510,Q8WWI5,O95470,O75306,Q9UNE7,P03886,Q5XKP0,P05067,O76024,P07602,P54802,P00403,Q96RL7,Q9H2C2,Q9NPL8,O60313,Q9Y487,O75503,P17900,P04062,O15118,Q9UBB4,Q08209
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
386,388,137,398,268,523,147,273,530,28,159,173,47,175,573,315,566,319,68,585,204,327,469,221,95,96,104,232,236,109,241,500,118,506,384,379
|
1054,506,530,137,602,236,3150,2491,566,241,327,670,2588,315,523,95,28,68,118,1158,204,386,469,2680,2033,1519,1846,3152,1303,273,3246,500,1965,1632,268,159,1101,2652,2322,1454,793,632,1498,2041,2913,1704,994,2629,47,2449,3303,753,221,1564,1852,1435,1455,2180,2596,1439,1145,2919,1282,2573,379,388,939,2367,711,175,147,969,2477,731,996,585,2717,3322,1710,700,2191,2192,1575,573,2768,940,929,96,1483,2942,2639,2987,2089,2160,104,232,3147,2311,173,384,1898,1899,1030,398,319,1118,2120,109,1447
|
0.2756661511961478,0.9058005368829619,0.8682363372946176,1.9814208160018005,0.779694821256333,1.5797113102117606,-1.1668478915554994,-0.5832023743822983,0.8177955706609692,1.5572509969346298,1.281273760705501,0.6769360722247575,-0.647131625751063,1.30474106378976,0.8807829276640542,2.2693262981715874,3.0624281306689123,2.525480253725994,2.1064111698932244,0.19218783473832943,1.6798031111121596,1.1625999707615722,0.9925796692463879,-0.6955235731118161,-0.31874711143957013,-0.05067325033674048,-0.22807885031082178,-1.1668478915554994,0.07909400602166337,1.4437304908127628,-1.380679358108941,0.9182717672838793,-0.2883747518392183,-0.12396926881478841,1.4551752366331643,1.8646386144308038,0.23406828346498643,-0.6793500706356256,-0.4729166554316845,-0.007112210270966405,0.5328060821965044,0.7285278893546684,-0.03611853455253771,-0.31874711143957013,-0.8596738042439521,-0.1535347647507937,0.31698540656083257,-0.6632195009402341,2.743817956942605,-0.5514878660885424,-1.640166986171383,0.5856054418382873,1.6132522522142752,-0.07988664715431047,-0.22807885031082178,0.007339737540638098,-0.007112210270966405,-0.3953451725415673,-0.647131625751063,0.007339737540638098,0.20617963072146406,-0.8596738042439521,0.09334491384878002,-0.631086208801837,1.1745691139378525,1.1625999707615722,0.3716510518956005,-0.4885500586033537,0.6379588946017836,1.789183956579087,1.939203453754038,0.3443787137519083,-0.5673244671099098,0.6118374126406803,0.31698540656083257,0.8051212350176506,-0.7117402486747223,-1.75491299162932,-0.1535347647507937,0.6509785063189131,-0.3953451725415673,-0.3953451725415673,-0.07988664715431047,0.8177955706609692,-0.7443040905812541,0.3716510518956005,0.3852422065417807,2.2693262981715874,-0.021598244629604746,-0.8763358915188677,-0.6632195009402341,-0.9265989667676673,-0.3339900772103585,-0.37994850970962596,2.2289873418727852,1.5909114869453034,-1.1493665932391064,-0.45732323785786155,1.8000185178422223,1.1745691139378525,-0.24309720612430855,-0.24309720612430855,0.3032430368863615,1.1506078804869229,1.30474106378976,0.23406828346498643,-0.34927116493347793,2.2087214952641787,0.007339737540638098
| 3,376
|
metalloprotease
| 8
| 27
| 2.794594
| 0.005196
|
O75844,P42892,Q9BYT8,Q9UIQ6,Q7Z2K6,P55786,Q9NZ08,Q5JRX3
|
Functions
|
Panther Protein class
|
panther_protein_class
|
71,107,271,213,276,151,314,381
|
922,1905,71,1174,1699,2536,1752,879,3232,1209,107,1756,151,388,381,1339,276,617,2460,1484,1150,271,1956,1991,314,213,1296
|
0.3852422065417807,-0.2581525139593801,2.457521700066298,0.17816419100440917,-0.1535347647507937,-0.6150830158119736,-0.1832436057353802,0.42583726441943925,-1.344508871789742,0.1500207496396212,2.2087214952641787,-0.1832436057353802,1.9179887298526617,1.1625999707615722,1.1745691139378525,0.06480999958601061,1.4322648574279548,0.7541640070071953,-0.5514878660885424,-0.021598244629604746,0.20617963072146406,1.4551752366331643,-0.27324496497470774,-0.2883747518392183,1.3164418516370977,1.6576974846458383,0.09334491384878002
| 3,376
|
Sphingolipid metabolism overview
| 7
| 9
| 2.794463
| 0.005199
|
Q96G23,Q06136,O15121,Q13510,Q16739,Q9NRA0,O95470
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
163,103,105,175,51,407,315
|
105,521,1781,315,103,175,51,163,407
|
2.21886249397109,0.8807829276640542,-0.19815223757022424,1.30474106378976,2.2289873418727852,1.789183956579087,2.706377290804834,1.8431719091236531,1.126554488303031
| 3,376
|
Sphingolipid metabolism integrated pathway
| 7
| 9
| 2.794463
| 0.005199
|
Q96G23,Q06136,O15121,Q13510,Q16739,Q9NRA0,O95470
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
163,103,105,175,51,407,315
|
105,521,1781,315,103,175,51,163,407
|
2.21886249397109,0.8807829276640542,-0.19815223757022424,1.30474106378976,2.2289873418727852,1.789183956579087,2.706377290804834,1.8431719091236531,1.126554488303031
| 3,376
|
Primary mitochondrial disease
| 37
| 102
| 2.793989
| 0.005206
|
Q96I36,Q9BUB7,Q9Y2R0,O14949,Q6P4A7,O43676,Q9Y6M9,P00846,Q53H12,Q96CU9,Q7KZN9,Q9UBX3,O75880,P20674,Q86Y39,O75306,Q8NI60,Q9NYY8,P03886,Q5XKP0,Q9BRT2,O75208,Q8NFF5,O43819,Q15526,Q9P0J0,P00403,Q9BQT8,P12235,Q07021,Q6DKK2,P13073,Q9NPL8,O60313,O95831,Q70HW3,P09001
|
Drugs and Diseases
|
Protein Atlas Disease involvement
|
protein_atlas_disease_involvement
|
517,645,10,18,152,25,282,28,290,562,572,59,188,317,62,566,452,589,68,585,714,455,722,602,731,93,95,475,97,729,224,100,232,236,362,248,631
|
1559,18,25,1603,602,236,455,1812,566,1324,1749,188,1326,362,95,28,68,2681,907,631,97,100,2289,3153,317,879,3023,3006,2322,2913,1969,2408,2364,3129,1538,3241,2130,753,1435,1456,2787,1919,729,1641,731,1822,290,996,3300,585,224,152,248,572,2816,62,1165,2219,722,452,1926,3202,1046,562,2024,517,2742,953,1863,1483,1150,2960,1768,475,714,1318,2089,645,744,1094,1321,2974,232,876,1254,589,2745,93,2529,59,2903,1993,1155,2398,10,1995,2512,1692,2994,2643,1838,282
|
-0.07988664715431047,3.3235076545102,3.106682006127666,-0.1092398235540067,0.779694821256333,1.5797113102117606,1.017153527787551,-0.21309725685462735,0.8177955706609692,0.06480999958601061,-0.1832436057353802,1.7347305225090166,0.06480999958601061,1.21033977687557,2.2693262981715874,3.0624281306689123,2.525480253725994,-0.6955235731118161,0.39880353572925303,0.7285278893546684,2.2592655177971985,2.2390960928105765,-0.45732323785786155,-1.1668478915554994,1.30474106378976,0.42583726441943925,-0.9772829358324227,-0.9603410571851295,-0.4729166554316845,-0.8596738042439521,-0.2883747518392183,-0.5199376859291878,-0.4885500586033537,-1.1319358181488326,-0.06526256357203314,-1.362566906250655,-0.364590575074656,0.5856054418382873,0.007339737540638098,-0.007112210270966405,-0.760651747905037,-0.2581525139593801,0.6118374126406803,-0.12396926881478841,0.6118374126406803,-0.21309725685462735,1.386191839289798,0.31698540656083257,-1.6212548839839795,0.8051212350176506,1.602091776312444,1.9073546394248442,1.5347102368011099,0.8177955706609692,-0.7770435603241972,2.62132664953133,0.19218783473832943,-0.41078076891872717,0.6249119037114952,1.0294042647856594,-0.2581525139593801,-1.2550231143250905,0.28946999971654247,0.8304441394676204,-0.3035420687482125,0.8933042921551931,-0.728000339684901,0.35802993391519033,-0.22807885031082178,-0.021598244629604746,0.20617963072146406,-0.8930439362355179,-0.1832436057353802,0.9802563479044419,0.6379588946017836,0.07909400602166337,-0.3339900772103585,0.7156700563298527,0.5987352995655117,0.2479654395213026,0.07909400602166337,-0.9097982049966251,1.5909114869453034,0.4393099348893643,0.12174807413919582,0.8051212350176506,-0.728000339684901,2.2793711942368797,-0.599121814464143,2.6498026320516255,-0.8430574101429883,-0.2883747518392183,0.20617963072146406,-0.5042236629761834,3.491878261337632,-0.2883747518392183,-0.5832023743822983,-0.13873418933689516,-0.9265989667676673,-0.6632195009402341,-0.21309725685462735,1.420778256383682
| 3,376
|
Cellular monovalent inorganic cation homeostasis
| 13
| 25
| 2.783465
| 0.005378
|
Q9HC07,Q9Y487,P05023,Q9Y6M7,P50897,Q05086,Q92544,O75503,Q8N511,Q15904,Q93050,P06576,P61421
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
43,109,707,726,47,740,435,241,83,595,55,751,655
|
241,991,707,993,751,818,2175,2006,47,2072,2131,1196,655,740,595,83,435,55,1685,43,1188,1350,109,3037,726
|
1.5572509969346298,0.31698540656083257,0.6379588946017836,0.31698540656083257,0.5856054418382873,0.5062366837929436,-0.3953451725415673,-0.3035420687482125,2.743817956942605,-0.3339900772103585,-0.364590575074656,0.1641085471368729,0.6898742644114918,0.5987352995655117,0.7924210222267182,2.3986898186378873,1.0538338490539432,2.6781524570436264,-0.13873418933689516,2.8088173906325995,0.17816419100440917,0.06480999958601061,2.2087214952641787,-0.9772829358324227,0.6249119037114952
| 3,376
|
golgi
| 26
| 65
| 2.772718
| 0.005559
|
P61019,Q9Y3E0,Q9NR31,Q8NBN3,Q15836,Q13190,P53367,Q5VW38,O15258,Q96K37,Q9Y5P4,O14735,O15126,Q8IXU6,Q9H0U4,Q15904,Q9NTJ5,Q9H2M9,O15127,P49755,Q9Y487,Q8WVM8,P61026,Q9Y371,P53365,Q8IZA0
|
Localization
|
OpenCell Localization
|
opencell_localization
|
767,547,546,32,559,304,686,52,565,586,842,448,579,597,471,595,472,864,856,610,109,889,495,638,507,253
|
1811,448,2513,1601,579,856,565,1605,991,1722,1934,2288,2430,2239,1453,2147,1038,1498,2447,610,507,686,1635,2326,1502,767,495,2366,1059,2596,1794,1540,304,1271,1089,2298,559,595,52,2082,2386,597,253,1220,32,889,1460,972,586,2090,471,864,1465,546,472,2484,1554,1389,1690,638,547,919,109,842,1747
|
-0.21309725685462735,1.0294042647856594,-0.599121814464143,-0.1092398235540067,0.8051212350176506,0.45275332185277023,0.8177955706609692,-0.1092398235540067,0.31698540656083257,-0.16837117607596028,-0.27324496497470774,-0.45732323785786155,-0.535692346636734,-0.42625550585234623,-0.007112210270966405,-0.37994850970962596,0.28946999971654247,-0.03611853455253771,-0.5514878660885424,0.7669425203474032,0.9058005368829619,0.6639708590611185,-0.12396926881478841,-0.4729166554316845,-0.03611853455253771,0.5724477159799228,0.9307180881219075,-0.4885500586033537,0.2756661511961478,-0.647131625751063,-0.19815223757022424,-0.06526256357203314,1.3397781272483118,0.1075628834780911,0.2479654395213026,-0.45732323785786155,0.8304441394676204,0.7924210222267182,2.6875745657573895,-0.3339900772103585,-0.5042236629761834,0.7924210222267182,1.5234094998830219,0.1500207496396212,3.0357290886065282,0.42583726441943925,-0.007112210270966405,0.3443787137519083,0.8051212350176506,-0.3339900772103585,0.9925796692463879,0.45275332185277023,-0.007112210270966405,0.8556644142476869,0.9925796692463879,-0.5673244671099098,-0.06526256357203314,0.03614204326984603,-0.13873418933689516,0.7285278893546684,0.8556644142476869,0.39880353572925303,2.2087214952641787,0.4795527769199012,-0.16837117607596028
| 3,376
|
Lipid biosynthetic process
| 65
| 146
| 2.759724
| 0.005785
|
Q10713,Q9P035,P11802,Q9H3P7,Q9UG56,Q9NXE4,P48651,O15269,P11413,Q92604,Q15738,Q92643,Q9NZ01,O15228,Q9NPH0,Q14534,Q9HCL2,Q86YN1,Q86SK9,Q9NRA0,Q53H12,Q96G23,Q9NVV0,Q8NCC3,Q9BYI3,Q99805,P09455,Q13510,Q8WTV0,Q16739,Q8WWI5,Q14457,O95470,O95749,Q16850,P00387,O14735,Q8NF37,Q8NBX0,O14734,P30536,P16435,Q9H7Z7,Q53GQ0,Q8WXW3,Q9NTJ5,Q15392,Q96PE3,Q9NX62,Q14739,Q9NTG7,P14174,Q14849,Q96N66,Q9H2C2,Q06136,O15121,Q96PU8,P37268,Q9C0D9,P35610,P04062,O60678,P04035,Q15800
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
388,266,648,396,528,667,141,521,393,663,658,277,278,529,24,153,27,154,280,407,290,163,170,689,692,46,174,175,300,51,573,440,315,316,65,321,448,332,462,578,334,456,599,465,466,472,87,216,219,347,351,481,98,225,104,103,105,369,238,239,501,118,630,251,126
|
738,1297,2202,3367,960,578,448,105,529,521,1781,630,2062,1373,2865,2263,2353,315,1587,316,2707,1099,321,251,118,1845,707,2680,174,393,648,481,802,2623,3296,456,2804,1013,2147,1429,2912,3188,2653,1245,334,896,501,897,238,775,1913,1194,141,1126,2008,1477,2995,1614,3308,3219,1794,103,388,3371,1269,175,3065,440,153,347,98,2664,2153,87,1311,658,126,51,1507,65,3143,465,290,1457,1621,280,1165,154,1022,462,689,1737,332,300,1763,1575,573,466,2899,663,277,900,1480,2195,163,225,216,369,702,1112,1549,2987,46,986,1114,3369,810,2392,1387,915,692,239,104,396,916,599,27,24,1203,407,351,472,1553,170,219,667,278,266,2484,1389,2347,528,1188,779,2617,2775
|
0.5987352995655117,0.07909400602166337,-0.41078076891872717,-4.151705872762363,0.3443787137519083,0.8051212350176506,1.0294042647856594,2.21886249397109,0.8682363372946176,0.8807829276640542,-0.19815223757022424,0.7285278893546684,-0.3339900772103585,0.03614204326984603,-0.8264864472557774,-0.44176959203476396,-0.4885500586033537,1.30474106378976,-0.09454567529886222,1.30474106378976,-0.7117402486747223,0.23406828346498643,1.2930183954698358,1.5234094998830219,2.1064111698932244,-0.22807885031082178,0.6379588946017836,-0.6955235731118161,1.789183956579087,1.1506078804869229,0.7027855534353731,0.9679086309299181,0.5195356321277029,-0.6632195009402341,-1.6024023498752415,1.017153527787551,-0.7770435603241972,0.3032430368863615,-0.37994850970962596,0.007339737540638098,-0.8596738042439521,-1.237284521255809,-0.6793500706356256,0.12174807413919582,1.2695070730093605,0.4123351763696069,0.9182717672838793,0.4123351763696069,1.5684911717900816,0.5592619976723756,-0.2581525139593801,0.1641085471368729,1.970892831816529,0.22013973023415834,-0.3035420687482125,-0.021598244629604746,-0.94344649290514,-0.1092398235540067,-1.678171482939842,-1.3085546915454922,-0.19815223757022424,2.2289873418727852,1.1625999707615722,-6.583513679554098,0.1075628834780911,1.789183956579087,-1.0283952575793793,1.0416310057595912,1.8967026461556973,1.245907190269227,2.249188800352927,-0.6793500706356256,-0.37994850970962596,2.339309921504243,0.07909400602166337,0.6898742644114918,2.0650208618258294,2.706377290804834,-0.03611853455253771,2.554385400886273,-1.1493665932391064,1.0048786958028963,1.386191839289798,-0.007112210270966405,-0.1092398235540067,1.420778256383682,0.19218783473832943,1.8967026461556973,0.3032430368863615,1.017153527787551,0.6639708590611185,-0.16837117607596028,1.281273760705501,1.3514137844149743,-0.1832436057353802,-0.07988664715431047,0.8177955706609692,1.0048786958028963,-0.8430574101429883,0.6898742644114918,1.4322648574279548,0.4123351763696069,-0.021598244629604746,-0.3953451725415673,1.8431719091236531,1.602091776312444,1.6355140571423021,1.21033977687557,0.6509785063189131,0.23406828346498643,-0.06526256357203314,-0.9265989667676673,2.781041140569378,0.3306972515746962,0.23406828346498643,-4.419544909473411,0.5195356321277029,-0.5042236629761834,0.03614204326984603,0.39880353572925303,0.6639708590611185,1.5684911717900816,2.2289873418727852,1.1506078804869229,0.39880353572925303,0.7924210222267182,3.097855519585872,3.141867551624668,0.1641085471368729,1.126554488303031,1.245907190269227,0.9925796692463879,-0.06526256357203314,1.8216320518149403,1.6243929881344374,0.6898742644114918,1.4322648574279548,1.466599174519213,-0.5673244671099098,0.03614204326984603,-0.4729166554316845,0.8807829276640542,0.17816419100440917,0.5592619976723756,-0.647131625751063,-0.7443040905812541
| 3,376
|
Visual loss
| 22
| 47
| 2.750947
| 0.005942
|
P51798,Q10713,P53701,P00846,P40939,O95140,Q15051,Q9NZJ7,P50897,Q8IY17,O14773,O75306,P03886,P04439,P07602,O15460,P00403,O60313,Q8TC12,O75503,Q96JJ3,P54098
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
640,388,142,28,794,670,805,173,47,700,61,566,68,468,469,590,95,236,628,241,377,753
|
2557,801,1054,61,590,236,566,1905,241,1011,670,95,3061,28,68,2825,468,469,2517,2319,3172,1497,2431,794,1194,47,1358,640,1128,142,753,2210,2271,388,2330,1920,3287,2477,805,700,628,1764,1927,377,2987,1254,173
|
-0.631086208801837,0.5195356321277029,0.2756661511961478,2.62132664953133,0.7924210222267182,1.5797113102117606,0.8177955706609692,-0.2581525139593801,1.5572509969346298,0.3032430368863615,0.6769360722247575,2.2693262981715874,-1.0283952575793793,3.0624281306689123,2.525480253725994,-0.7934797786581159,0.9925796692463879,0.9925796692463879,-0.599121814464143,-0.4729166554316845,-1.20196329291841,-0.03611853455253771,-0.535692346636734,0.5328060821965044,0.1641085471368729,2.743817956942605,0.050492732938221645,0.7156700563298527,0.22013973023415834,1.970892831816529,0.5856054418382873,-0.41078076891872717,-0.44176959203476396,1.1625999707615722,-0.4729166554316845,-0.2581525139593801,-1.5648744215576544,-0.5673244671099098,0.5195356321277029,0.6509785063189131,0.7413591680028151,-0.1832436057353802,-0.2581525139593801,1.1865154018947937,-0.9265989667676673,0.12174807413919582,1.8000185178422223
| 3,376
|
mitochondria
| 8
| 11
| 2.749096
| 0.005976
|
Q9NVH1,Q9Y277,P21796,P45880,Q969Q5,Q15388,Q9NR31,Q8IWA4
|
Localization
|
OpenCell Localization
|
opencell_localization
|
483,136,41,44,16,242,546,605
|
1325,670,41,44,1923,242,605,16,546,483,136
|
0.06480999958601061,0.6769360722247575,2.8548455407684523,2.7903132643602064,-0.2581525139593801,1.5572509969346298,0.779694821256333,3.3405432490399405,0.8556644142476869,0.9679086309299181,1.991931331193204
| 3,376
|
Retrograde vesicle mediated transport golgi to endoplasmic reticulum
| 8
| 28
| 2.746697
| 0.00602
|
O15258,Q96RQ1,Q9H4A6,Q9Y282,Q8TD16,Q9H9E3,Q9P2W9,Q969X5
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
565,168,74,75,372,187,22,311
|
1811,565,1533,2239,2035,1038,1704,1916,2243,610,1635,2366,938,1310,2246,1108,372,889,1460,311,1074,168,74,187,1078,22,1554,75
|
-0.21309725685462735,0.8177955706609692,-0.06526256357203314,-0.42625550585234623,-0.31874711143957013,0.28946999971654247,-0.1535347647507937,-0.2581525139593801,-0.42625550585234623,0.7669425203474032,-0.12396926881478841,-0.4885500586033537,0.3716510518956005,0.07909400602166337,-0.42625550585234623,0.23406828346498643,1.1984389259522672,0.42583726441943925,-0.007112210270966405,1.3281208444722734,0.2618313464396684,1.8216320518149403,2.437971309123152,1.7456588522658942,0.2618313464396684,3.1942884268912617,-0.06526256357203314,2.437971309123152
| 3,376
|
Phospholipid metabolic process
| 31
| 77
| 2.740401
| 0.006136
|
Q10713,Q9Y263,Q9UG56,Q9NXE4,P48651,O15269,Q92604,Q92643,Q9NRA0,O15228,Q9NPH0,Q86YN1,Q9HCL2,Q9NVV0,Q96DA6,Q8NCC3,Q9BYI3,Q8WTV0,Q8WWI5,Q14457,Q96S52,O95749,O14735,Q8NF37,Q9NTJ5,Q96PE3,Q9NX62,Q96N66,P37268,Q9C0D9,Q8NHP8
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
388,646,528,667,141,521,663,277,407,529,24,154,27,170,563,689,692,300,573,440,702,316,448,332,472,216,219,225,238,239,115
|
2886,2202,448,529,521,1781,2062,2865,1587,316,2707,2680,802,2804,3139,2147,2625,897,238,794,1793,141,3303,2995,3219,1794,388,3065,440,2664,1457,1621,154,700,2156,689,1737,332,115,300,1763,1575,573,663,277,900,1480,563,225,216,702,1549,892,986,1114,3369,810,1387,692,2229,239,916,27,24,1203,407,472,1553,170,219,667,2484,1389,528,1188,2233,646
|
-0.8430574101429883,-0.41078076891872717,1.0294042647856594,0.8682363372946176,0.8807829276640542,-0.19815223757022424,-0.3339900772103585,-0.8264864472557774,-0.09454567529886222,1.30474106378976,-0.7117402486747223,-0.6955235731118161,0.5195356321277029,-0.7770435603241972,-1.1493665932391064,-0.37994850970962596,-0.6632195009402341,0.4123351763696069,1.5684911717900816,0.5328060821965044,-0.19815223757022424,1.970892831816529,-1.640166986171383,-0.94344649290514,-1.3085546915454922,-0.19815223757022424,1.1625999707615722,-1.0283952575793793,1.0416310057595912,-0.6793500706356256,-0.007112210270966405,-0.1092398235540067,1.8967026461556973,0.6509785063189131,-0.37994850970962596,0.6639708590611185,-0.16837117607596028,1.281273760705501,2.127005524105473,1.3514137844149743,-0.1832436057353802,-0.07988664715431047,0.8177955706609692,0.6898742644114918,1.4322648574279548,0.4123351763696069,-0.021598244629604746,0.8304441394676204,1.602091776312444,1.6355140571423021,0.6509785063189131,-0.06526256357203314,0.42583726441943925,0.3306972515746962,0.23406828346498643,-4.419544909473411,0.5195356321277029,0.03614204326984603,0.6639708590611185,-0.41078076891872717,1.5684911717900816,0.39880353572925303,3.097855519585872,3.141867551624668,0.1641085471368729,1.126554488303031,0.9925796692463879,-0.06526256357203314,1.8216320518149403,1.6243929881344374,0.6898742644114918,-0.5673244671099098,0.03614204326984603,0.8807829276640542,0.17816419100440917,-0.41078076891872717,0.7156700563298527
| 3,376
|
Alcohol metabolic process
| 26
| 82
| 2.733454
| 0.006267
|
Q10713,P11413,Q8NBN7,Q6NUM9,Q9NRA0,Q14534,Q8WTV0,Q13510,Q16850,P00387,P05067,P16435,P51648,Q15392,Q96PE3,Q14739,Q9NX62,Q9Y394,Q14849,Q9H2C2,P37268,P35610,P04062,O15118,P04035,Q15800
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
388,393,274,405,407,153,300,175,65,321,204,456,80,87,216,347,219,228,98,104,238,501,118,506,251,126
|
2886,506,521,1781,2316,2062,1373,2865,2263,2353,2707,764,321,251,118,204,2169,1519,393,1964,802,2355,2623,456,2826,1013,2912,2562,2755,501,238,1913,633,1194,3140,2008,3025,2449,3303,80,1477,2995,3168,937,1455,2571,967,3219,1794,388,1269,175,2331,3065,153,347,98,1336,2664,87,658,126,1507,65,2953,405,274,628,300,216,2942,3132,2391,1093,915,104,1203,407,219,2347,2232,228
|
-0.8430574101429883,0.9058005368829619,0.8807829276640542,-0.19815223757022424,-0.4729166554316845,-0.3339900772103585,0.03614204326984603,-0.8264864472557774,-0.44176959203476396,-0.4885500586033537,-0.7117402486747223,0.5724477159799228,1.2930183954698358,1.5234094998830219,2.1064111698932244,1.6798031111121596,-0.3953451725415673,-0.05067325033674048,1.1506078804869229,-0.2883747518392183,0.5195356321277029,-0.4885500586033537,-0.6632195009402341,1.017153527787551,-0.7934797786581159,0.3032430368863615,-0.8596738042439521,-0.631086208801837,-0.7443040905812541,0.9182717672838793,1.5684911717900816,-0.2581525139593801,0.7285278893546684,0.1641085471368729,-1.1493665932391064,-0.3035420687482125,-0.9772829358324227,-0.5514878660885424,-1.640166986171383,2.4183608115792006,-0.021598244629604746,-0.94344649290514,-1.1843800211435078,0.3716510518956005,-0.007112210270966405,-0.631086208801837,0.3443787137519083,-1.3085546915454922,-0.19815223757022424,1.1625999707615722,0.1075628834780911,1.789183956579087,-0.4729166554316845,-1.0283952575793793,1.8967026461556973,1.245907190269227,2.249188800352927,0.06480999958601061,-0.6793500706356256,2.339309921504243,0.6898742644114918,2.0650208618258294,-0.03611853455253771,2.554385400886273,-0.8930439362355179,1.126554488303031,1.4437304908127628,0.7413591680028151,1.3514137844149743,1.6355140571423021,-0.8763358915188677,-1.1319358181488326,-0.5042236629761834,0.2479654395213026,0.39880353572925303,2.2289873418727852,0.1641085471368729,1.126554488303031,1.6243929881344374,-0.4729166554316845,-0.41078076891872717,1.602091776312444
| 3,376
|
Nuclear bodies
| 30
| 130
| 2.579083
| 0.009906
|
O75153,Q9UQ84,Q16637,Q9H9B1,Q9H993,Q96RL1,Q92994,Q8IXH7,Q9BTY7,P09132,Q9Y4E8,P52788,O75695,Q15345,P33240,Q9Y4C2,P20585,Q96MF7,O95248,Q8NEM2,P15927,Q8IYQ7,Q9BXW9,Q92889,Q14457,Q13867,P56282,Q96FJ2,Q8WYQ5,Q15554
|
Localization
|
Protein Atlas Subcellular
|
protein_atlas_subcellular_location_all
|
6,8,144,146,286,283,419,307,37,40,449,299,57,64,192,338,191,329,75,465,82,326,358,356,225,460,95,109,385,125
|
1719,663,1720,769,1569,2398,1102,1313,621,6,2703,1924,57,952,1501,75,2092,2315,2851,40,1653,1111,82,1115,1193,191,1868,2945,2990,192,1391,732,2592,1994,2854,553,2741,299,2221,95,2492,900,2662,1747,1336,2598,2456,1810,1592,2110,3175,1218,460,2165,2556,225,1886,1946,2917,493,64,688,125,850,144,2331,1062,1684,2230,2880,2562,1601,746,998,2232,307,326,2529,465,2068,2921,563,385,356,419,700,868,647,109,804,869,1772,329,1830,283,2986,1482,870,2128,37,2023,1295,651,358,1423,1424,2649,1619,1555,286,146,810,1164,2185,936,3110,3048,940,1166,1242,1633,8,1781,2783,1716,338,449,1380,2508,947
|
-0.044067709882776376,0.5112695688752548,-0.044067709882776376,0.44109416141745744,0.024568563594607476,-0.4509476953948541,0.2665828304056785,0.16252714442340316,0.5464352780067219,5.668921347145836,-0.7508459131023316,-0.14658317757621844,2.1032963978654777,0.3362265384392549,0.05897311520212943,1.9550615206595165,-0.24856208147325873,-0.3837126835348374,-0.9484981778200601,2.589429347324161,-0.009778528071157864,0.2665828304056785,1.9181046502934387,0.2665828304056785,0.23184255137823337,1.1879115385730248,-0.11247050468159725,-1.111904464356793,-1.2418153541664156,1.1879115385730248,0.12795283674857258,0.47615574384811765,-0.6180818497524784,-0.18063605997536256,-0.9484981778200601,0.6169209415124207,-0.7839103701087301,0.9365850713308754,-0.31625251437501656,1.6972353652536702,-0.5179624508175903,0.37112918611708395,-0.6845661608764068,-0.044067709882776376,0.16252714442340316,-0.6180818497524784,-0.4844823065569105,-0.07829852404852866,0.024568563594607476,-0.24856208147325873,-2.7830742431174413,0.23184255137823337,0.7230299094324006,-0.2824364084187739,-0.5847616569451121,1.1158699245679418,-0.11247050468159725,-0.14658317757621844,-1.0466801603121254,0.687609972296476,2.066176983291154,0.5112695688752548,1.5143440063059697,0.40608518560932166,1.4051312298119452,-0.3837126835348374,0.30137762402187557,-0.009778528071157864,-0.31625251437501656,-0.9812721551424736,-0.5847616569451121,0.024568563594607476,0.47615574384811765,0.3362265384392549,-0.31625251437501656,0.9365850713308754,0.9008708365095625,-0.5513887106082873,0.7230299094324006,-0.214628861006375,-1.0466801603121254,0.6169209415124207,0.8295874872385776,0.8652048733693636,0.7940189877570858,0.5112695688752548,0.40608518560932166,0.5464352780067219,1.6239497465096042,0.44109416141745744,0.40608518560932166,-0.044067709882776376,0.9008708365095625,-0.07829852404852866,0.9723472767243138,-1.2094038315054783,0.0934346845102919,0.40608518560932166,-0.24856208147325873,2.7025328021822936,-0.18063605997536256,0.19715718713126482,0.5464352780067219,0.8652048733693636,0.12795283674857258,0.12795283674857258,-0.6513498381747402,0.024568563594607476,0.05897311520212943,0.9723472767243138,1.4051312298119452,0.44109416141745744,0.2665828304056785,-0.2824364084187739,0.37112918611708395,-1.8813926738256954,-1.4674997876375357,0.37112918611708395,0.2665828304056785,0.23184255137823337,0.024568563594607476,5.388288416474245,-0.044067709882776376,-0.8169252168872264,-0.009778528071157864,0.9008708365095625,0.7584996889713711,0.16252714442340316,-0.5179624508175903,0.37112918611708395
| 3,205
|
Cellular response to vascular endothelial growth factor stimulus
| 6
| 8
| 2.097844
| 0.035919
|
Q16539,Q12948,Q96E22,P04083,P04792,P23634
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
496,223,536,70,9,22
|
1720,70,9,22,223,557,496,536
|
-0.044067709882776376,1.992059338814486,5.308362296900556,3.311292975041059,1.1158699245679418,0.6169209415124207,0.687609972296476,0.6522402054291618
| 3,205
|
Regulation of lysosomal lumen ph
| 6
| 7
| 2.365115
| 0.018024
|
O75503,Q9HC07,O75787,Q9NWW5,P50897,Q8N511
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
128,289,290,235,41,16
|
128,290,41,16,406,289,235
|
1.9093648873212545,1.0835998439422212,3.2418655988469802,4.159089053264923,0.8274975960490513,1.1029433898907732,1.2937201610174092
| 3,210
|
Dysostosis multiplex
| 6
| 7
| 2.365115
| 0.018024
|
P16278,P10619,O00754,P15586,P04066,P54802
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
131,38,198,246,284,125
|
198,284,38,246,131,125,406
|
1.4429978380230684,1.1029433898907732,3.315858403774397,1.2179808768128926,1.8919256615910303,1.9441300559071935,0.8274975960490513
| 3,210
|
transmembrane signal receptor
| 7
| 8
| 2.30665
| 0.021074
|
Q9NZT2,O75787,O15173,Q99720,O00264,Q9UMX5,P15260
|
Functions
|
Panther Protein class
|
panther_protein_class
|
294,290,229,10,137,172,15
|
137,229,290,15,434,10,294,172
|
1.8217862056621752,1.2937201610174092,1.0835998439422212,4.239282271600796,0.7671267334341764,4.4887817989782315,1.0835998439422212,1.6075749697690414
| 3,210
|
Sphingolipid metabolism
| 6
| 10
| 2.302038
| 0.021333
|
Q16739,Q13510,P04062,P07602,P17900,Q06136
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
32,75,47,48,111,90
|
422,2652,141,47,48,111,90,75,32,1057
|
0.7873051138665256,-0.6847656636079493,1.8041546249047102,3.076843619635619,3.031288546754357,2.081710348546229,2.3170155929508804,2.4485152075098346,3.432969472681017,0.20004755229564355
| 3,210
|
Vacuolar acidification
| 6
| 10
| 2.183956
| 0.028965
|
Q93050,O75503,Q9NWW5,P50897,Q8N511,Q9Y487
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
64,128,235,41,16,150
|
128,290,41,2180,16,64,235,1549,150,2683
|
1.9093648873212545,1.0835998439422212,3.2418655988469802,-0.36894409591271893,4.159089053264923,2.673764653157473,1.2937201610174092,-0.06723513363812487,1.7687738657447782,-0.6847656636079493
| 3,210
|
calmodulin-related
| 7
| 10
| 2.148088
| 0.031707
|
P80303,Q9BPX6,Q02818,Q8IYU8,Q14257,Q9BRK5,O43852
|
Functions
|
Panther Protein class
|
panther_protein_class
|
4,133,13,207,84,247,340
|
340,1754,378,4,13,84,2633,207,133,247
|
0.9270379483271718,-0.1817089841565943,0.847512453464809,5.1520987989651195,4.345144496536938,2.3500868340317056,-0.6599314453348567,1.405947875030295,1.8919256615910303,1.2179808768128926
| 3,210
|
Sphingolipid metabolism in senescence
| 9
| 12
| 2.135112
| 0.032752
|
Q16739,O15121,P16278,Q96G23,Q13510,P04062,P24941,P11802,Q06136
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
32,97,131,136,75,47,305,342,90
|
97,422,47,342,131,305,902,933,90,75,32,136
|
2.2337520122835284,0.7873051138665256,3.076843619635619,0.9270379483271718,1.8919256615910303,1.0252702855408282,0.2869328465936709,0.26531099795843516,2.3170155929508804,2.4485152075098346,3.432969472681017,1.8393788820543948
| 3,210
|
Membrane lipid catabolic process
| 7
| 11
| 2.128993
| 0.033255
|
P50897,Q13510,O95470,P04062,P17900,P06280,Q99735
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
41,75,141,47,111,245,255
|
141,47,284,245,900,2659,111,41,75,255,2196
|
1.8041546249047102,3.076843619635619,1.1029433898907732,1.2179808768128926,0.2869328465936709,-0.6847656636079493,2.081710348546229,3.2418655988469802,2.4485152075098346,1.1989282768348137,-0.36894409591271893
| 3,210
|
Bulbar signs
| 7
| 12
| 2.09055
| 0.036568
|
P35637,Q9Y263,Q99720,P04062,P03886,P07602,P06753
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
414,456,10,47,14,48,399
|
442,14,47,399,48,1805,414,1294,1486,10,1021,456
|
0.746893082576532,4.239282271600796,3.076843619635619,0.8274975960490513,3.031288546754357,-0.2048342170031588,0.8074286080916745,0.04537661015180214,-0.044566305353490585,4.4887817989782315,0.22186887095956295,0.746893082576532
| 3,210
|
Nonalcoholic fatty liver disease
| 22
| 48
| 4.161549
| 0.000032
|
P21912,P22695,P51970,O95298,Q9P0J0,P60953,O43676,P15954,O14949,P14406,Q9UDW1,O75380,P49840,P63000,P31040,O00217,P31930,Q86Y39,O95299,P20674,O75251,P00403
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
496,129,499,256,14,270,36,414,43,44,46,434,187,438,211,92,218,233,475,495,493,366
|
92,668,1528,43,36,1710,493,822,434,1768,256,475,366,1906,1197,714,1352,786,44,523,2304,414,1040,495,496,129,1783,211,2895,218,2355,1426,1916,614,187,902,499,1297,270,438,1672,2277,1059,233,2064,14,46,1346
|
1.9517715396466142,0.5034926557472869,-0.013762661187869209,2.768680735877916,3.0612894149232734,-0.0997257723165647,0.6764533068474775,0.3883303529448472,0.7630278449071122,-0.1283651722112755,1.1388686667807886,0.7053046416328677,0.8785548612321639,-0.18562193543010477,0.1583723191033171,0.47469099999317105,0.07226934763416325,0.41710978314444397,2.768680735877916,0.6476088916672819,-0.38579613781079947,0.7918996031387205,0.24454771184920537,0.6764533068474775,0.6764533068474775,1.660952980636015,-0.1283651722112755,1.2837036718300274,-0.9559499207681041,1.254724699862172,-0.4143647846958465,0.043584231076383116,-0.18562193543010477,0.5611177432905115,1.399678167637441,0.33079418522630977,0.6764533068474775,0.10096234789685095,1.1099198375930281,0.7630278449071122,-0.07107893462425983,-0.3572206950736908,0.24454771184920537,1.2257516709181544,-0.24284976542710374,3.9121315146567643,2.73944346623199,0.10096234789685095
| 3,210
|
Electron transport
| 21
| 47
| 4.066161
| 0.000048
|
P21912,Q9H3N1,P51970,P22695,O95298,Q9P0J0,Q16134,O43169,O43676,O14949,Q9UDW1,O75380,O95864,P31040,O00217,P31930,Q86Y39,Q99757,O95299,O75251,P00403
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
496,264,499,129,256,14,391,145,36,43,46,434,195,211,92,218,233,360,475,493,366
|
92,668,43,145,1897,36,1710,493,822,434,1768,256,475,195,366,1350,1197,1145,2304,1040,496,497,129,1783,211,218,1596,1295,1426,614,499,1297,391,2277,1059,2772,1942,233,2851,2242,360,1017,264,14,46,2338,1346
|
1.9517715396466142,0.5034926557472869,2.768680735877916,1.5738113969759262,-0.18562193543010477,3.0612894149232734,-0.0997257723165647,0.6764533068474775,0.3883303529448472,0.7630278449071122,-0.1283651722112755,1.1388686667807886,0.7053046416328677,1.3416792792210046,0.8785548612321639,0.07226934763416325,0.1583723191033171,0.1870894267741931,-0.38579613781079947,0.24454771184920537,0.6764533068474775,0.6764533068474775,1.660952980636015,-0.1283651722112755,1.2837036718300274,1.254724699862172,-0.042424588305331204,0.10096234789685095,0.043584231076383116,0.5611177432905115,0.6764533068474775,0.10096234789685095,0.8496631638098913,-0.3572206950736908,0.24454771184920537,-0.7566787356245731,-0.18562193543010477,1.2257516709181544,-0.8705836214377505,-0.32863839725396865,0.9074531014169275,0.27328873734257736,1.1388686667807886,3.9121315146567643,2.73944346623199,-0.38579613781079947,0.10096234789685095
| 3,210
|
Abnormality of the mitochondrion
| 37
| 98
| 3.968965
| 0.000072
|
P21912,P26358,P51970,Q9Y4W6,P22570,Q9BUB7,O43772,Q4J6C6,O95298,Q9UMS0,Q9P0J0,Q16134,Q8IUX1,Q9Y584,Q08426,O43676,Q969Y2,P49748,Q70HW3,O75380,Q00325,O60783,Q9UBX3,P31040,O00217,Q86SX6,P46976,Q86Y39,Q99757,O95299,Q9H845,P12235,P40939,P49821,P20674,O75251,P00403
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
496,498,499,400,497,536,9,10,256,399,14,391,531,25,29,36,177,174,58,434,556,433,73,211,92,623,219,233,360,475,381,114,613,614,495,493,366
|
92,1894,668,36,9,433,493,822,434,1768,2348,256,475,366,1350,785,980,1199,1716,3111,114,786,1145,1040,495,496,497,679,498,1783,983,211,2617,2465,1295,613,1484,1597,219,174,614,1668,2410,499,2411,1733,1545,869,1297,1494,556,29,1434,2159,1618,391,1059,2771,2980,1215,2718,10,2629,2719,1376,58,2377,654,623,233,531,3144,1261,1744,177,2851,852,1947,1875,1634,360,768,536,2487,1120,381,3155,1339,14,2491,73,399,2457,2458,400,25,1893,1346
|
1.9517715396466142,-0.18562193543010477,0.5034926557472869,3.0612894149232734,4.471263356608017,0.7630278449071122,0.6764533068474775,0.3883303529448472,0.7630278449071122,-0.1283651722112755,-0.4143647846958465,1.1388686667807886,0.7053046416328677,0.8785548612321639,0.07226934763416325,0.41710978314444397,0.27328873734257736,0.1583723191033171,-0.0997257723165647,-1.778625708526751,1.7772173493984713,0.41710978314444397,0.1870894267741931,0.24454771184920537,0.6764533068474775,0.6764533068474775,0.6764533068474775,0.5034926557472869,0.6764533068474775,-0.1283651722112755,0.27328873734257736,1.2837036718300274,-0.614159800319998,-0.5000305276776785,0.10096234789685095,0.5611177432905115,0.014906920281284118,-0.042424588305331204,1.254724699862172,1.4577000206031279,0.5611177432905115,-0.07107893462425983,-0.4429266939583211,0.6764533068474775,-0.4429266939583211,-0.0997257723165647,-0.013762661187869209,0.35955846414598713,0.10096234789685095,0.014906920281284118,0.6187714535547078,3.295675789963257,0.043584231076383116,-0.30004918409410347,-0.042424588305331204,0.8496631638098913,0.24454771184920537,-0.7566787356245731,-1.1265272435002622,0.1583723191033171,-0.6996898275229555,4.353447366494844,-0.614159800319998,-0.6996898275229555,0.07226934763416325,2.5057048530603376,-0.4143647846958465,0.532301591048701,0.5611177432905115,1.2257516709181544,0.6476088916672819,-2.1178248450474757,0.12966331135686696,-0.0997257723165647,1.4577000206031279,-0.8705836214377505,0.3883303529448472,-0.18562193543010477,-0.15699720383151142,-0.042424588305331204,0.9074531014169275,0.4458966875052482,0.6476088916672819,-0.5000305276776785,0.21581458325266947,0.8785548612321639,-2.258966469671713,0.10096234789685095,3.9121315146567643,-0.5000305276776785,2.243098964599965,0.8496631638098913,-0.4714819228517013,-0.4714819228517013,0.8496631638098913,3.5303175206480657,-0.15699720383151142,0.10096234789685095
| 3,210
|
Subsets and Splits
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