term stringlengths 2 121 | overlap int64 6 281 | setsize int64 7 499 | score float64 1.96 10.6 | pval float64 0 0.05 | edge stringlengths 41 1.97k | type stringclasses 5
values | subtype stringclasses 24
values | subtype_key stringclasses 24
values | edge_idxs stringlengths 11 1.17k | ann_idxs stringlengths 19 2.31k | ann_vals stringlengths 124 9.94k | sig_size int64 2.2k 3.73k |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Ion transmembrane transport | 71 | 167 | 3.098232 | 0.001947 | Q9BPX6,P51798,Q8N4V1,P30825,Q9C0H2,Q9Y277,Q9HD26,P11413,Q9H2D1,Q9Y619,P78417,Q8IYU8,Q9NRA0,Q6P4A7,P61421,P24539,P00846,O60831,Q4KMQ2,P07384,Q9UDW1,Q9HD20,P53007,P21796,Q9HC07,P45880,Q9NVV0,Q9UJS0,P46934,P16615,Q7KZN9,Q9UBX3,P98194,Q13423,Q9UHG3,P20674,Q9HC21,O75844,Q86VD7,Q6KCM7,P56385,Q96GC9,P05067,P05023,Q9Y6M7,P5613... | Processes and pathways | GO Biological process | msigdb_gobp | 512,640,1,130,135,136,526,393,15,272,402,533,407,152,655,408,28,413,540,548,36,165,425,41,43,44,170,437,557,178,572,59,568,189,63,317,193,71,72,76,582,78,204,707,726,721,594,342,733,731,473,95,375,97,475,609,100,354,358,499,618,234,489,490,508,112,124,364,249,248,632 | 1423,2058,1559,1243,2513,1189,1450,816,727,342,2377,413,473,2648,1812,1905,489,71,1141,1397,124,358,499,784,95,28,707,993,204,609,946,751,2965,548,2207,765,2002,907,818,1785,1909,393,97,375,100,178,1910,2005,3139,845,317,2404,3051,3209,41,408,3023,490,2240,2653,2930,2129,130,1209,632,2684,981,1498,2041,3078,1704,44,557... | 0.007339737540638098,-0.3339900772103585,-0.07988664715431047,0.12174807413919582,-0.599121814464143,0.1641085471368729,-0.007112210270966405,0.5062366837929436,0.6118374126406803,1.245907190269227,-0.5042236629761834,1.102408190994822,0.9802563479044419,-0.6793500706356256,-0.21309725685462735,-0.2581525139593801,0.94... | 3,376 |
Protein insertion into er membrane | 7 | 15 | 3.089545 | 0.002005 | Q8N4V1,Q7L5D6,O43681,Q9NPA0,Q96A33,Q15629,P46379 | Processes and pathways | GO Biological process | msigdb_gobp | 1,296,137,397,243,85,409 | 2124,137,1098,409,431,1437,2601,85,1133,296,1,1200,243,397,903 | -0.364590575074656,1.9814208160018005,0.23406828346498643,1.1144929997983144,1.0538338490539432,0.007339737540638098,-0.647131625751063,2.3789579376592007,0.22013973023415834,1.3630278999226435,3.918017746429074,0.1641085471368729,1.5572509969346298,1.1506078804869229,0.4123351763696069 | 3,376 |
Organelle membrane contact site | 11 | 17 | 3.080805 | 0.002064 | Q14849,Q96TC7,Q5XKP0,Q96N66,P27824,P51572,O96008,Q15388,Q9NTJ5,O43865,Q9Y320 | Localization | GO Cellular component | msigdb_gocc | 98,226,585,225,671,673,523,242,472,342,480 | 1393,1323,342,1840,523,671,673,98,242,585,1221,225,808,226,1549,472,480 | 0.021757766555510514,0.06480999958601061,1.245907190269227,-0.22807885031082178,0.8807829276640542,0.6769360722247575,0.6769360722247575,2.249188800352927,1.5572509969346298,0.8051212350176506,0.1500207496396212,1.602091776312444,0.5195356321277029,1.602091776312444,-0.06526256357203314,0.9925796692463879,0.98025634790... | 3,376 |
Exopeptidase activity | 14 | 32 | 3.078321 | 0.002082 | P42785,P10619,Q9HB40,O75844,Q0VDG4,O75976,Q969V3,Q9UIQ6,Q7Z2K6,Q9H3G5,P55786,Q9NZ08,P09960,O14773 | Functions | GO Molecular function | msigdb_gomf | 378,132,227,71,488,554,177,213,276,576,151,314,252,61 | 61,71,554,1699,252,132,2536,3232,2128,1211,378,1195,151,488,2181,1542,1339,276,999,617,1711,177,2460,742,576,2117,227,1956,2345,1991,314,213 | 2.62132664953133,2.457521700066298,0.8304441394676204,-0.1535347647507937,1.5234094998830219,2.012900196950257,-0.6150830158119736,-1.344508871789742,-0.364590575074656,0.1500207496396212,1.1745691139378525,0.1641085471368729,1.9179887298526617,0.9555364168366788,-0.3953451725415673,-0.06526256357203314,0.0648099995860... | 3,376 |
Ion channel transport | 15 | 29 | 3.072709 | 0.002121 | P51798,Q4KMQ2,Q9HD20,Q9C0H2,Q9NW15,Q9Y487,P27105,Q99576,P16615,Q15904,Q93050,P61421,P35670,P98194,Q13555 | Processes and pathways | Reactome Pathways | msigdb_reactome | 640,540,165,135,234,109,490,207,178,595,55,655,632,568,254 | 707,993,178,845,2404,3051,490,2129,632,1498,2041,640,2131,655,568,2075,1146,254,595,540,55,207,135,1803,165,234,1350,109,1810 | 0.6379588946017836,0.31698540656083257,1.7674589112604508,0.46616755845459307,-0.5199376859291878,-1.0113097535490851,0.9431396034941706,-0.364590575074656,0.7285278893546684,-0.03611853455253771,-0.31874711143957013,0.7156700563298527,-0.364590575074656,0.6898742644114918,0.8177955706609692,-0.3339900772103585,0.20617... | 3,376 |
Action tremor | 23 | 59 | 3.068645 | 0.00215 | Q9BUB7,O43681,Q14108,P00846,Q9NR77,Q9H6K4,Q99720,O95140,Q96DA6,Q9NZJ7,Q9BYI3,Q6PJG6,O14773,Q5T8D3,Q9UNE7,O75306,P03886,P07602,O75027,Q96RL7,Q9NW15,Q9UBB4,Q5JRX3 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 645,137,147,28,31,160,164,670,563,173,692,571,61,318,319,566,68,469,473,96,234,384,381 | 3284,61,2123,1694,137,473,566,961,991,670,1934,28,68,1158,469,2517,1965,1452,1847,1632,1429,2592,2501,793,3078,2656,2565,753,2411,1564,2271,2573,147,1062,2186,381,318,1709,2717,571,700,2156,2767,563,96,2942,2639,164,645,692,160,1956,31,234,173,384,319,1370,1296 | -1.5648744215576544,2.62132664953133,-0.364590575074656,-0.1535347647507937,1.9814208160018005,0.9802563479044419,0.8177955706609692,0.3443787137519083,0.31698540656083257,0.6769360722247575,-0.27324496497470774,3.0624281306689123,2.525480253725994,0.19218783473832943,0.9925796692463879,-0.599121814464143,-0.2883747518... | 3,376 |
Transport of small molecules | 57 | 155 | 3.067206 | 0.002161 | Q9BPX6,P51798,Q8N4V1,P63218,P30825,Q10713,Q9C0H2,Q9Y277,P09601,P51665,Q8IYU8,P40855,P61421,Q9UL46,Q9UBV2,Q4KMQ2,Q9BUN8,P61289,Q9HD20,P30519,P49721,P21796,P45880,Q8WTV0,P16615,Q93050,P28072,Q8WWI5,Q9UBX3,P98194,P20618,P05023,Q9Y6M7,Q99576,Q15904,P35611,P35613,O75027,P12235,P28070,P05141,O95202,Q92530,Q8TDW0,Q9NW15,Q9Y48... | Processes and pathways | Reactome Pathways | msigdb_reactome | 512,640,1,641,130,388,135,136,9,401,533,149,655,281,289,540,416,674,165,38,166,41,44,300,178,55,430,573,59,568,330,707,726,207,595,720,603,473,97,353,609,358,231,618,234,109,490,112,506,503,624,501,375,505,248,632,254 | 921,3046,2779,505,2780,506,1189,1300,473,1905,1373,1843,3049,2353,3020,358,2678,1699,707,993,609,2170,1302,765,2002,2288,9,1303,819,97,375,1875,178,1910,2005,1877,845,1966,330,2404,3051,3173,41,1669,895,2038,2292,490,2040,353,430,624,1245,38,2129,130,1475,501,720,1376,603,632,2756,2265,1498,3240,2041,149,1500,44,1611,1... | 0.3852422065417807,-1.0113097535490851,-0.760651747905037,0.9058005368829619,-0.760651747905037,0.9058005368829619,0.1641085471368729,0.07909400602166337,0.9802563479044419,-0.2581525139593801,0.03614204326984603,-0.22807885031082178,-1.0113097535490851,-0.4885500586033537,-0.9772829358324227,1.222218044879942,-0.69552... | 3,376 |
Abnormal circulating cholesterol concentration | 13 | 30 | 3.066704 | 0.002164 | Q9NZJ7,P37268,Q9UJS0,O75431,Q8N511,Q15904,Q9H9E3,Q15392,P07602,Q15800,Q14739,P50402,Q9NVI7 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 173,238,437,240,83,595,187,87,469,126,347,220,446 | 240,1698,1427,469,238,3240,1704,950,220,2449,886,1455,1794,1215,2014,1820,347,87,658,126,595,83,1073,1222,1137,187,446,173,2347,437 | 1.5572509969346298,-0.1535347647507937,0.007339737540638098,0.9925796692463879,1.5684911717900816,-1.362566906250655,-0.1535347647507937,0.35802993391519033,1.6132522522142752,-0.5514878660885424,0.42583726441943925,-0.007112210270966405,-0.19815223757022424,0.1500207496396212,-0.3035420687482125,-0.21309725685462735,1... | 3,376 |
Ragged red muscle fibers | 7 | 18 | 3.06074 | 0.002208 | P12235,P03886,Q9H2D1,Q9Y5P6,Q70HW3,P00846,P00403 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 97,68,15,341,248,28,95 | 2144,669,362,95,28,68,97,2322,2130,753,2074,248,2457,1483,1768,15,1155,341 | -0.37994850970962596,0.6769360722247575,1.21033977687557,2.2693262981715874,3.0624281306689123,2.525480253725994,2.2592655177971985,-0.4729166554316845,-0.364590575074656,0.5856054418382873,-0.3339900772103585,1.5347102368011099,-0.5514878660885424,-0.021598244629604746,-0.1832436057353802,3.349044243996922,0.206179630... | 3,376 |
Endoplasmic reticulum tubular network | 7 | 14 | 3.055833 | 0.002244 | Q9NQC3,Q9H6H4,Q8NHH9,Q9H2C2,P61026,P50402,Q6NUK4 | Localization | GO Cellular component | msigdb_gocc | 66,261,134,104,495,220,415 | 1323,220,495,558,2075,1733,909,415,134,1487,104,261,1774,66 | 0.06480999958601061,1.6132522522142752,0.9307180881219075,0.8304441394676204,-0.3339900772103585,-0.16837117607596028,0.39880353572925303,1.0902999671477054,1.991931331193204,-0.021598244629604746,2.2289873418727852,1.500746929971123,-0.1832436057353802,2.554385400886273 | 3,376 |
Nucleobase containing compound transmembrane transporter activity | 8 | 15 | 3.055798 | 0.002245 | P12235,Q9HC21,Q9BSK2,Q86VD7,Q6KCM7,L0R6Q1,Q9H2D1,Q8TB61 | Functions | GO Molecular function | msigdb_gomf | 97,193,3,72,76,333,15,112 | 333,1189,727,609,97,375,3078,966,76,679,72,112,3,15,193 | 1.2695070730093605,0.1641085471368729,0.6118374126406803,0.7669425203474032,2.2592655177971985,1.1865154018947937,-1.0455292059601446,0.3443787137519083,2.428173597886573,0.6769360722247575,2.457521700066298,2.1679949059006707,3.8868120422021692,3.349044243996922,1.72378323442192 | 3,376 |
Oxidoreduction driven active transmembrane transporter activity | 12 | 33 | 3.051298 | 0.002279 | P51970,Q9UDW1,P03886,P13073,Q7KZN9,P00403,O95168,O43676,Q9Y6M9,P20674,Q9P0J0,O96000 | Functions | GO Molecular function | msigdb_gomf | 538,36,68,100,572,95,343,25,282,317,93,30 | 1559,1243,763,25,1603,1812,566,1324,343,1561,1326,30,95,68,907,1909,100,3153,317,3006,1209,2408,3129,538,1435,731,2762,1822,572,93,36,1993,282 | -0.07988664715431047,0.12174807413919582,0.5724477159799228,3.106682006127666,-0.1092398235540067,-0.21309725685462735,0.8177955706609692,0.06480999958601061,1.245907190269227,-0.07988664715431047,0.06480999958601061,3.0446410783605184,2.2693262981715874,2.525480253725994,0.39880353572925303,-0.2581525139593801,2.23909... | 3,376 |
Electron transfer activity | 17 | 57 | 3.050174 | 0.002287 | P51970,Q9UDW1,P03886,P13073,P14406,O15121,P21912,O75306,P16435,Q7KZN9,P00403,O95168,O43676,Q9Y6M9,P20674,Q9P0J0,O96000 | Functions | GO Molecular function | msigdb_gomf | 538,36,68,100,8,105,268,566,456,572,95,343,25,282,317,93,30 | 1559,1243,105,590,1299,763,25,1603,2316,1812,566,1324,343,1561,1326,30,1327,95,68,2169,907,1519,1909,1964,100,3137,8,2623,456,3153,317,268,2174,1848,3006,3093,2322,1209,3101,2408,710,3129,538,1435,2075,2043,731,1363,2762,1822,1858,572,93,36,1993,282,904 | -0.07988664715431047,0.12174807413919582,2.21886249397109,0.7924210222267182,0.07909400602166337,0.5724477159799228,3.106682006127666,-0.1092398235540067,-0.4729166554316845,-0.21309725685462735,0.8177955706609692,0.06480999958601061,1.245907190269227,-0.07988664715431047,0.06480999958601061,3.0446410783605184,0.064809... | 3,376 |
Golgi apparatus | 115 | 335 | 3.047683 | 0.002306 | Q8N4V1,Q9Y3A6,O60499,Q9HD26,P80303,Q68CQ7,Q5VZ89,Q9P2W9,Q9Y3E0,Q9NR31,O95197,Q8NBN3,Q8NCH0,Q9NPR9,Q15836,Q9HC07,Q99805,P50897,P46934,Q16739,Q5VW38,Q93050,O43505,Q13464,O14773,P98194,O15258,Q96K37,O15126,Q15363,Q9H4A6,Q9Y282,Q92520,O15260,Q9H7Z7,Q15392,O95249,P35613,Q96RL7,O95070,P49755,Q9H2C2,Q14999,Q7LGA3,Q9NQX7,Q8TB6... | Localization | GO Cellular component | msigdb_gocc | 1,520,11,526,19,20,532,22,547,546,29,32,34,35,559,43,46,47,557,51,52,55,553,569,61,568,565,586,579,73,74,75,77,79,599,87,88,603,96,99,610,104,616,110,111,112,116,118,119,638,636,123,634,632,667,666,146,147,150,651,158,673,168,172,691,690,686,685,180,181,187,186,703,717,200,204,205,708,707,212,219,239,241,253,275,273,28... | 333,2286,1903,1054,2202,146,2164,1811,2558,448,1394,61,1207,1601,486,506,579,856,565,79,1602,3245,553,3238,2061,116,2862,651,302,11,2167,1190,1451,2287,1605,1533,241,2492,3180,99,29,1473,88,1934,2354,1057,1587,963,2678,118,468,707,204,785,3362,1666,2288,2430,818,708,819,1355,273,2804,1935,2239,685,2035,947,3209,3173,21... | 1.2695070730093605,-0.45732323785786155,-0.2581525139593801,0.2756661511961478,-0.41078076891872717,1.939203453754038,-0.3953451725415673,-0.21309725685462735,-0.631086208801837,1.0294042647856594,0.021757766555510514,2.62132664953133,0.1500207496396212,-0.1092398235540067,0.9555364168366788,0.9058005368829619,0.805121... | 3,376 |
Areflexia of lower limbs | 12 | 25 | 3.046488 | 0.002315 | Q96RL7,O95394,P12235,Q15067,Q16637,O95140,Q13501,O60313,Q9NR77,Q15041,Q15120,Q9H6K4 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 96,695,97,255,549,670,711,236,31,508,698,160 | 236,1373,991,670,695,1262,97,2565,965,753,1564,1852,2210,1759,711,508,255,698,549,1737,96,1483,160,31,1718 | 1.5797113102117606,0.03614204326984603,0.31698540656083257,0.6769360722247575,0.6509785063189131,0.1075628834780911,2.2592655177971985,-0.631086208801837,0.3443787137519083,0.5856054418382873,-0.07988664715431047,-0.22807885031082178,-0.41078076891872717,-0.1832436057353802,0.6379588946017836,0.9058005368829619,1.51208... | 3,376 |
Glycerophospholipid biosynthesis | 17 | 29 | 3.038742 | 0.002376 | Q53H12,O14735,Q96N66,Q8NF37,Q8IV08,Q8WWI5,Q8NCC3,Q9UG56,P48651,Q99829,Q9C0D9,P43304,Q92604,O15228,Q9NPH0,Q9HCL2,P40939 | Processes and pathways | Reactome Pathways | msigdb_reactome | 290,448,225,332,158,573,689,528,141,742,239,633,663,529,24,27,794 | 448,529,2000,2682,897,794,633,141,2243,3079,1309,290,1621,158,689,332,1763,573,663,225,742,986,810,2229,239,27,24,1553,528 | 1.0294042647856594,0.8682363372946176,-0.3035420687482125,-0.6955235731118161,0.4123351763696069,0.5328060821965044,0.7285278893546684,1.970892831816529,-0.42625550585234623,-1.0455292059601446,0.07909400602166337,1.386191839289798,-0.1092398235540067,1.8753446974883117,0.6639708590611185,1.281273760705501,-0.183243605... | 3,376 |
Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen | 10 | 32 | 3.02243 | 0.002508 | Q16850,Q8N543,P30519,P09601,O15121,Q9NVH6,Q6UW02,Q86SK9,Q14534,Q15800 | Functions | GO Molecular function | msigdb_gomf | 65,390,38,9,105,203,54,280,153,126 | 1997,960,105,590,1869,2167,1099,1302,9,766,456,38,937,2687,2075,153,126,65,1443,2872,1458,54,2155,280,1646,390,1648,3249,2309,203,1255,2703 | -0.3035420687482125,0.3443787137519083,2.21886249397109,0.7924210222267182,-0.24309720612430855,-0.3953451725415673,0.23406828346498643,0.07909400602166337,3.508477031496731,0.5724477159799228,1.017153527787551,2.9005459852632884,0.3716510518956005,-0.6955235731118161,-0.3339900772103585,1.8967026461556973,2.0650208618... | 3,376 |
Sphingolipid metabolism in senescence | 6 | 14 | 3.012687 | 0.002589 | Q96G23,Q06136,O15121,Q13510,Q16739,P04062 | Processes and pathways | WikiPathways | msigdb_wp | 163,103,105,175,51,118 | 105,521,118,1783,648,273,1910,1193,2006,775,103,175,51,163 | 2.21886249397109,0.8807829276640542,2.1064111698932244,-0.19815223757022424,0.7027855534353731,1.4437304908127628,-0.2581525139593801,0.1641085471368729,-0.3035420687482125,0.5592619976723756,2.2289873418727852,1.789183956579087,2.706377290804834,1.8431719091236531 | 3,376 |
Mitochondrial carrier protein [IPR002067] | 11 | 13 | 3.008398 | 0.002626 | Q9BQT8,Q6NUK1,Q9HC21,P05141,P12235,Q86VD7,P53007,O75746,Q6KCM7,Q9UJS0,P12236 | Sequence | InterPro Family | interpro_family | 475,679,193,609,97,72,425,489,76,437,375 | 727,489,609,97,375,425,76,679,72,475,1171,193,437 | 0.6118374126406803,0.9431396034941706,0.7669425203474032,2.2592655177971985,1.1865154018947937,1.0660128924007646,2.428173597886573,0.6769360722247575,2.457521700066298,0.9802563479044419,0.19218783473832943,1.72378323442192,1.0538338490539432 | 3,376 |
Monovalent inorganic cation homeostasis | 15 | 28 | 3.007335 | 0.002635 | Q9Y5X3,Q9HC07,Q9Y487,P05023,Q9Y6M7,Q93063,P50897,Q92544,Q05086,Q8N511,Q15904,Q93050,O75503,P06576,P61421 | Processes and pathways | GO Biological process | msigdb_gobp | 392,43,109,707,726,690,47,435,740,83,595,55,241,751,655 | 241,991,1374,707,993,751,818,2175,2006,47,2072,2131,1196,655,740,595,83,435,55,690,1685,43,1188,1350,109,392,3037,726 | 1.5572509969346298,0.31698540656083257,0.03614204326984603,0.6379588946017836,0.31698540656083257,0.5856054418382873,0.5062366837929436,-0.3953451725415673,-0.3035420687482125,2.743817956942605,-0.3339900772103585,-0.364590575074656,0.1641085471368729,0.6898742644114918,0.5987352995655117,0.7924210222267182,2.398689818... | 3,376 |
Sphingolipid metabolism | 9 | 13 | 2.999676 | 0.002703 | Q06136,O43681,O15121,Q13510,Q16739,P16278,P04062,Q9NRA0,O95470 | Processes and pathways | KEGG Pathways | msigdb_kegg | 103,137,105,175,51,273,118,407,315 | 105,521,1781,137,315,118,785,273,103,175,51,407,667 | 2.21886249397109,0.8807829276640542,-0.19815223757022424,1.9814208160018005,1.30474106378976,2.1064111698932244,0.5460481617509392,1.4437304908127628,2.2289873418727852,1.789183956579087,2.706377290804834,1.126554488303031,0.6898742644114918 | 3,376 |
Abnormal biliary tract morphology | 11 | 25 | 2.988572 | 0.002803 | P50542,P14174,Q10713,O43933,P09601,O43681,Q9NZJ7,Q14108,P04062,P07602,Q14739 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 286,481,388,513,9,137,173,147,118,469,347 | 137,513,1698,118,469,9,481,2848,2432,2685,286,1358,753,388,1162,147,347,585,1683,1047,1026,173,1490,1155,781 | 1.9814208160018005,0.8933042921551931,-0.1535347647507937,2.1064111698932244,0.9925796692463879,3.508477031496731,0.9679086309299181,-0.8099606559026915,-0.535692346636734,-0.6955235731118161,1.3977418285889271,0.050492732938221645,0.5856054418382873,1.1625999707615722,0.19218783473832943,1.939203453754038,1.2459071902... | 3,376 |
primary active transporter | 11 | 23 | 2.987283 | 0.002815 | Q9BUN8,Q9NS69,O60888,Q8N4H5,Q9Y5J7,O96008,P16615,Q15388,Q6P4A7,P35670,P98194 | Functions | Panther Protein class | panther_protein_class | 416,2,131,12,429,523,178,242,152,632,568 | 131,1325,523,707,993,1874,178,845,632,2131,568,242,1478,152,12,2387,1024,416,1895,1346,2344,2,429 | 2.012900196950257,0.06480999958601061,0.8807829276640542,0.6379588946017836,0.31698540656083257,-0.24309720612430855,1.7674589112604508,0.46616755845459307,0.7285278893546684,-0.364590575074656,0.8177955706609692,1.5572509969346298,-0.021598244629604746,1.9073546394248442,3.4250546344122745,-0.5042236629761834,0.303243... | 3,376 |
Serine hydrolase activity | 10 | 17 | 2.981406 | 0.002869 | P42785,P10619,Q9HB40,P67812,O75976,Q5JRX3,Q9H3G5,O43464,O14773,P48147 | Functions | GO Molecular function | msigdb_gomf | 378,132,227,7,554,381,576,530,61,474 | 61,530,554,132,1751,2128,2432,378,474,1105,7,1887,634,381,999,576,227 | 2.62132664953133,0.8682363372946176,0.8304441394676204,2.012900196950257,-0.1832436057353802,-0.364590575074656,-0.535692346636734,1.1745691139378525,0.9802563479044419,0.23406828346498643,3.6071872129131113,-0.24309720612430855,0.7285278893546684,1.1745691139378525,0.31698540656083257,0.8177955706609692,1.602091776312... | 3,376 |
Mitochondrial complex iv assembly | 8 | 16 | 2.978215 | 0.002899 | Q96I36,P13073,P14406,Q9Y2R0,Q9P0S2,Q7KZN9,P20674,P00403 | Processes and pathways | WikiPathways | msigdb_wp | 517,100,8,10,139,572,317,95 | 1559,602,95,1909,100,8,1175,317,731,572,517,1318,139,943,10,904 | -0.07988664715431047,0.779694821256333,2.2693262981715874,-0.2581525139593801,2.2390960928105765,3.549788972453769,0.17816419100440917,1.30474106378976,0.6118374126406803,0.8177955706609692,0.8933042921551931,0.07909400602166337,1.9814208160018005,0.3716510518956005,3.491878261337632,0.4123351763696069 | 3,376 |
Cytoprotection by hmox1 | 18 | 68 | 2.971134 | 0.002967 | P28070,P13073,P30519,P49721,P20618,P09601,Q92530,O75376,Q9P0S2,O00487,P51665,Q99436,P28072,Q9UL46,Q8TCT9,O75880,P20674,P00403 | Processes and pathways | Reactome Pathways | msigdb_reactome | 353,100,38,166,330,9,231,267,139,505,401,503,430,281,122,188,317,95 | 921,3046,2779,1559,505,1243,2780,1300,602,267,1843,188,95,9,1909,100,1175,1877,2682,330,317,1669,895,2038,2292,2040,353,430,624,38,2756,3336,2913,1500,1611,1881,166,401,1501,2731,1636,674,1730,1567,2132,1212,1309,1334,2106,2542,2107,2896,1283,1618,2133,731,1180,122,231,517,2461,503,2115,1318,139,281,1868,904 | 0.3852422065417807,-1.0113097535490851,-0.760651747905037,-0.07988664715431047,0.9058005368829619,0.12174807413919582,-0.760651747905037,0.07909400602166337,0.779694821256333,1.4551752366331643,-0.22807885031082178,1.7347305225090166,2.2693262981715874,3.508477031496731,-0.2581525139593801,2.2390960928105765,0.17816419... | 3,376 |
Nucleotide transport | 11 | 15 | 2.966019 | 0.003017 | Q6NUK1,Q9HC21,P05141,Q9BSK2,P12235,Q86VD7,Q8TDW0,Q6KCM7,Q9H2D1,Q8TB61,P12236 | Processes and pathways | GO Biological process | msigdb_gobp | 679,193,609,3,97,72,618,76,15,112,375 | 1189,727,609,97,375,3078,1214,76,679,72,112,618,3,15,193 | 0.1641085471368729,0.6118374126406803,0.7669425203474032,2.2592655177971985,1.1865154018947937,-1.0455292059601446,0.1500207496396212,2.428173597886573,0.6769360722247575,2.457521700066298,2.1679949059006707,0.7541640070071953,3.8868120422021692,3.349044243996922,1.72378323442192 | 3,376 |
Secretory granule membrane | 21 | 73 | 2.955058 | 0.003126 | P42785,Q969Q5,Q9Y2Q5,Q4KMQ2,P30519,Q9NZJ7,Q93050,O00264,Q8NF37,O15126,Q15363,P10253,O15260,P07602,Q07065,P35613,O15121,P27105,P61026,Q9NQX7,Q5T9A4 | Localization | GO Cellular component | msigdb_gocc | 378,16,285,540,38,173,55,198,332,579,73,329,79,469,89,603,105,490,495,111,509 | 2645,198,105,579,79,1189,2377,1190,694,2000,2491,991,3020,963,469,329,708,877,1355,3224,934,1398,2035,490,38,2129,1968,603,2069,378,1970,610,1754,2072,1104,2471,1971,495,1637,1972,3263,1940,1402,1674,89,1214,2330,1071,2250,2077,2273,73,540,3227,509,1890,332,1221,838,55,16,1985,742,974,2580,1774,111,173,2484,2617,285,18... | -0.6793500706356256,1.7018315064972644,2.21886249397109,0.8051212350176506,2.4183608115792006,0.1641085471368729,-0.5042236629761834,0.1641085471368729,0.6509785063189131,-0.3035420687482125,-0.5832023743822983,0.31698540656083257,-0.9772829358324227,0.3443787137519083,0.9925796692463879,1.281273760705501,0.63795889460... | 3,376 |
Tclin | 19 | 89 | 2.952711 | 0.00315 | P31350,P00813,O43676,Q9Y6M9,O96000,P21964,P38435,Q99720,P49721,P20839,Q16739,Q06203,Q86Y39,P03886,P20618,P10253,O95168,Q9P0J0,P04035 | Drugs and Diseases | Pharos IDG Category | pharos_protein_category | 262,138,25,282,30,159,162,164,166,303,51,308,62,68,330,329,343,93,251 | 1559,763,25,1603,1425,1812,566,1324,343,1561,1326,30,764,1327,2803,138,68,251,1068,707,993,2169,946,785,979,2846,2319,1785,329,2650,2146,3164,2890,648,719,802,2623,3153,330,303,159,2173,1787,1669,2652,624,3006,1633,262,2208,162,775,3140,166,3129,1159,786,1431,538,2131,1196,1435,1213,1018,924,2329,308,1675,569,1019,1569... | -0.07988664715431047,0.5724477159799228,3.106682006127666,-0.1092398235540067,0.007339737540638098,-0.21309725685462735,0.8177955706609692,0.06480999958601061,1.245907190269227,-0.07988664715431047,0.06480999958601061,3.0446410783605184,0.5724477159799228,0.06480999958601061,-0.7770435603241972,1.9814208160018005,2.525... | 3,376 |
Calcium ion transport | 18 | 60 | 2.950352 | 0.003174 | Q9BPX6,Q4KMQ2,O95202,O75844,P21796,Q9HC07,P11413,Q9NVV0,Q6KCM7,O76024,Q96GC9,P30536,P78417,P16615,Q8IYU8,Q9NRA0,Q13555,Q08209 | Processes and pathways | GO Biological process | msigdb_gobp | 512,540,358,71,41,43,393,170,76,327,78,334,402,178,533,407,254,379 | 1054,1034,2377,1905,71,327,358,1374,993,2965,2207,2002,1785,2100,393,1727,178,1910,2005,934,3139,845,41,2240,2653,334,2129,1497,1704,1433,803,3263,1437,1379,402,568,1438,2573,379,3317,254,2478,540,76,1249,2635,533,1001,733,1576,78,1686,512,43,407,170,2233,1599,1690,1296 | 0.2756661511961478,0.28946999971654247,-0.5042236629761834,-0.2581525139593801,2.457521700066298,1.281273760705501,1.222218044879942,0.03614204326984603,0.31698540656083257,-0.9097982049966251,-0.41078076891872717,-0.3035420687482125,-0.19815223757022424,-0.34927116493347793,1.1506078804869229,-0.16837117607596028,1.76... | 3,376 |
Transport vesicle | 32 | 94 | 2.946257 | 0.003216 | Q9BT78,O60499,Q9HD26,O00461,P61421,Q9NR31,Q92905,Q15836,P50897,Q13190,P20337,Q96A57,Q9Y3B3,Q9Y6Y8,O15126,P49257,Q15363,P05067,P10321,O76024,O15260,O43760,Q9H0U4,P04439,O95249,P49755,O15027,Q7L0J3,P61026,O43752,Q9GZY8,Q99523 | Localization | GO Cellular component | msigdb_gocc | 525,11,526,146,655,546,422,559,47,304,685,186,320,717,579,331,73,204,708,327,79,84,471,468,88,610,486,367,495,116,373,636 | 1054,146,1811,3060,486,579,79,1298,1602,2061,116,84,2490,11,1451,2287,2144,1533,327,1722,88,1844,1963,2678,468,204,2288,2430,1785,708,877,1355,845,685,1815,2035,947,2240,2537,1038,2041,1916,331,610,47,2072,1613,2409,1104,2471,1635,2326,2831,1971,495,1637,655,2366,2810,1059,2596,1130,304,1071,2933,3083,1284,2017,2837,73... | 0.2756661511961478,1.939203453754038,-0.21309725685462735,-1.0283952575793793,0.9555364168366788,0.8051212350176506,2.4183608115792006,0.07909400602166337,-0.1092398235540067,-0.3339900772103585,2.116716699323345,2.3789579376592007,-0.5832023743822983,3.450194354038298,-0.007112210270966405,-0.45732323785786155,-0.3799... | 3,376 |
Ceramide biosynthetic process | 9 | 12 | 2.94318 | 0.003249 | Q53H12,Q96G23,O15121,Q13510,O15269,Q16739,P04062,Q9NRA0,Q9NTG7 | Processes and pathways | GO Biological process | msigdb_gobp | 290,163,105,175,521,51,118,407,351 | 105,521,1781,118,1269,175,51,290,163,407,351,667 | 2.21886249397109,0.8807829276640542,-0.19815223757022424,2.1064111698932244,0.1075628834780911,1.789183956579087,2.706377290804834,1.386191839289798,1.8431719091236531,1.126554488303031,1.245907190269227,0.6898742644114918 | 3,376 |
mitochondrial carrier protein | 6 | 9 | 2.939886 | 0.003283 | Q9HC21,Q9BSK2,Q86VD7,Q9NZJ7,Q6KCM7,Q9Y6C9 | Functions | Panther Protein class | panther_protein_class | 193,3,72,173,76,120 | 869,76,679,248,72,3,193,173,120 | 0.4393099348893643,2.428173597886573,0.6769360722247575,1.5347102368011099,2.457521700066298,3.8868120422021692,1.72378323442192,1.8000185178422223,2.1064111698932244 | 3,376 |
Protein transmembrane import into intracellular organelle | 10 | 15 | 2.936769 | 0.003317 | O60830,P50542,O43615,O43933,Q99595,Q96DA6,O96008,O95831,Q15388,O14925 | Processes and pathways | GO Biological process | msigdb_gobp | 0,286,356,513,4,563,523,362,242,156 | 156,356,513,0,1325,362,523,3062,286,242,604,2387,563,4,2344 | 1.8860326867293702,1.222218044879942,0.8933042921551931,3.918017746429074,0.06480999958601061,1.21033977687557,0.8807829276640542,-1.0283952575793793,1.3977418285889271,1.5572509969346298,0.779694821256333,-0.5042236629761834,0.8304441394676204,3.8081377581322435,-0.4729166554316845 | 3,376 |
Translocation | 15 | 48 | 2.933035 | 0.003357 | O60830,Q9NS69,Q99595,O43615,Q96DA6,Q9Y5L4,Q9Y5J7,Q99442,Q9BTX1,Q8TD16,Q15629,Q9Y5J9,O14925,Q8N1F7,Q3ZCQ8 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 0,2,4,356,563,668,429,534,340,372,85,157,156,510,604 | 1996,156,1532,356,0,2168,1874,1792,1634,820,3094,1357,1105,886,2968,1437,1729,1504,828,85,604,1248,1823,1509,510,1289,1167,372,1951,1168,3282,681,563,1184,534,824,4,340,2641,1275,894,2,2799,2673,2261,429,157,668 | -0.3035420687482125,1.8860326867293702,-0.06526256357203314,1.222218044879942,3.918017746429074,-0.3953451725415673,-0.24309720612430855,-0.19815223757022424,-0.12396926881478841,0.5062366837929436,-1.062711887611437,0.050492732938221645,0.23406828346498643,0.42583726441943925,-0.9097982049966251,0.007339737540638098,-... | 3,376 |
Endomembrane system organization | 76 | 195 | 2.931325 | 0.003375 | P61019,Q8N4V1,Q9Y3A6,Q9H6H4,Q8NHH9,Q9Y2U8,O43681,Q9NPA0,Q9NXE4,Q9H267,Q14108,Q9P2W9,Q9UID3,Q5JRA6,P46379,O95197,Q6NUK4,Q4KMQ2,P50542,O94901,Q9P253,Q9H6U6,Q7L5D6,Q9NVV0,Q96CP7,Q96ED9,Q00765,Q2M389,P16615,Q16739,Q7Z3D4,Q13190,Q9H9E3,Q86XL3,P49069,Q9BSR8,O14657,Q9Y3B3,Q9NQC3,Q9UH99,Q9Y6Y8,Q96MW5,Q9Y5P4,O75844,Q8N3F8,Q1536... | Processes and pathways | GO Biological process | msigdb_gobp | 767,1,520,261,134,780,137,397,667,666,147,22,150,796,409,29,415,540,286,537,814,811,296,170,171,172,558,688,178,51,180,304,187,305,431,703,182,320,66,197,717,840,842,71,200,73,74,711,577,331,78,79,209,84,85,470,220,737,222,610,486,104,616,106,105,743,495,113,498,243,116,374,638,771,508,510 | 1393,577,2645,3038,1054,2164,2558,182,1394,2513,1352,1601,486,105,79,1662,2124,1586,137,116,84,1098,1695,2287,1605,2491,1426,1533,2442,2168,71,1534,537,1722,29,1934,963,1698,1518,2207,178,1910,3039,1632,2147,2175,2006,113,1210,2208,2447,3078,1704,1793,409,1915,1430,431,331,610,220,286,965,2072,1673,2244,470,2295,767,19... | 0.021757766555510514,0.8051212350176506,-0.6793500706356256,-0.9942724075500117,0.2756661511961478,-0.3953451725415673,-0.631086208801837,1.7456588522658942,0.021757766555510514,-0.599121814464143,0.050492732938221645,-0.1092398235540067,0.9555364168366788,2.21886249397109,2.4183608115792006,-0.13873418933689516,-0.364... | 3,376 |
Golgi organization | 24 | 65 | 2.931018 | 0.003379 | P61019,Q9Y3A6,Q8NHH9,Q9UID3,Q9P2W9,Q9H6U6,Q13190,Q7Z3D4,Q9H9E3,Q9BSR8,Q9Y3B3,Q9Y6Y8,P49257,Q15363,Q9H4A6,Q96GC9,O15260,P49755,O15027,Q14999,Q9BVK6,Q53FT3,O43752,Q9UL15 | Processes and pathways | GO Biological process | msigdb_gobp | 767,520,134,150,22,811,304,180,187,703,320,717,331,73,74,78,79,610,486,616,743,498,116,374 | 2164,1394,1601,486,79,1662,116,2287,1605,1533,1518,2175,2006,2208,2447,1704,1430,331,610,965,2295,767,1059,1615,938,2329,1540,2246,304,1760,1060,616,73,498,2047,2386,180,2765,1948,2421,1649,134,2306,1460,2085,78,1074,840,3098,2794,703,1114,743,74,811,1465,187,1028,22,150,374,3324,520,320,717 | -0.3953451725415673,0.021757766555510514,-0.1092398235540067,0.9555364168366788,2.4183608115792006,-0.13873418933689516,2.116716699323345,-0.45732323785786155,-0.1092398235540067,-0.06526256357203314,-0.05067325033674048,-0.3953451725415673,-0.3035420687482125,-0.41078076891872717,-0.5514878660885424,-0.153534764750793... | 3,376 |
Delusions | 7 | 17 | 2.927871 | 0.003413 | P21964,Q96RL7,O43681,Q9NZJ7,Q9UJS0,P04062,P07602 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 159,96,137,173,437,118,469 | 2674,137,118,469,2033,159,1211,1704,514,1758,2078,1651,96,1466,173,1867,437 | -0.6955235731118161,1.9814208160018005,2.1064111698932244,0.9925796692463879,-0.31874711143957013,1.8646386144308038,0.1500207496396212,-0.1535347647507937,0.8933042921551931,-0.1832436057353802,-0.3339900772103585,-0.12396926881478841,2.2693262981715874,-0.007112210270966405,1.8000185178422223,-0.22807885031082178,1.0... | 3,376 |
Hyperlipidemia | 10 | 30 | 2.920531 | 0.003494 | P28070,O75844,P49257,P23786,O75431,P31751,P50416,P22830,O95470,P50402 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 353,71,331,265,240,113,307,376,315,220 | 2123,1450,240,71,315,1698,785,1427,376,265,353,1633,113,1878,3240,331,220,307,2868,2014,2214,1820,970,2455,1222,1764,900,1137,437,1421 | -0.364590575074656,-0.007112210270966405,1.5572509969346298,2.457521700066298,1.30474106378976,-0.1535347647507937,0.5460481617509392,0.007339737540638098,1.1865154018947937,1.466599174519213,1.2340738196350072,-0.12396926881478841,2.157772335864085,-0.24309720612430855,-1.362566906250655,1.281273760705501,1.6132522522... | 3,376 |
Phospholipid metabolism | 8 | 17 | 2.918594 | 0.003516 | O14735,Q96N66,Q8NF37,Q9UG56,P48651,Q9C0D9,Q9NPH0,Q9HCL2 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 448,225,332,528,141,239,24,27 | 448,897,141,1621,332,1763,663,1480,225,986,810,239,27,24,1203,1553,528 | 1.0294042647856594,0.4123351763696069,1.970892831816529,-0.1092398235540067,1.281273760705501,-0.1832436057353802,0.6898742644114918,-0.021598244629604746,1.602091776312444,0.3306972515746962,0.5195356321277029,1.5684911717900816,3.097855519585872,3.141867551624668,0.1641085471368729,-0.06526256357203314,0.880782927664... | 3,376 |
Retrograde transport endosome to golgi | 14 | 38 | 2.916417 | 0.003541 | Q8NBN3,Q9Y5X3,Q15836,P49257,O60499,Q13190,O15260,P53367,O75503,O60749,O43752,Q9UID3,O95249,Q4J6C6 | Processes and pathways | GO Biological process | msigdb_gobp | 32,392,559,331,11,304,79,686,241,623,116,150,88,634 | 79,1602,116,1079,1695,11,623,1841,241,88,2035,2447,331,2072,1613,686,2596,304,1382,969,559,634,1198,1824,1596,2421,32,1460,1953,929,743,1578,2511,1256,150,3312,1295,392 | 2.4183608115792006,-0.1092398235540067,2.116716699323345,0.2479654395213026,-0.1535347647507937,3.450194354038298,0.7413591680028151,-0.22807885031082178,1.5572509969346298,2.32935923806442,-0.31874711143957013,-0.5514878660885424,1.281273760705501,-0.3339900772103585,-0.1092398235540067,0.6639708590611185,-0.647131625... | 3,376 |
Cholesterol binding | 6 | 13 | 2.915808 | 0.003548 | Q14849,P21796,P45880,P30536,Q14108,P35610 | Functions | GO Molecular function | msigdb_gomf | 98,41,44,334,147,501 | 506,1373,2353,2207,41,1429,334,501,44,1455,147,98,2229 | 0.9058005368829619,0.03614204326984603,-0.4885500586033537,-0.41078076891872717,2.8548455407684523,0.007339737540638098,1.2695070730093605,0.9182717672838793,2.7903132643602064,-0.007112210270966405,1.939203453754038,2.249188800352927,-0.41078076891872717 | 3,376 |
Tetrapyrrole metabolic process | 9 | 19 | 2.915735 | 0.003549 | O00264,P30519,Q9P0S9,P09601,Q96EY8,P30536,P22830,Q99707,O75027 | Processes and pathways | GO Biological process | msigdb_gobp | 198,38,463,9,297,334,376,443,473 | 198,2059,473,2752,2033,9,376,38,334,1211,1501,572,297,443,1689,463,2529,2395,1447 | 1.7018315064972644,-0.3339900772103585,0.9802563479044419,-0.7443040905812541,-0.31874711143957013,3.508477031496731,1.1865154018947937,2.9005459852632884,1.2695070730093605,0.1500207496396212,-0.03611853455253771,0.8177955706609692,1.3630278999226435,1.0416310057595912,-0.13873418933689516,1.017153527787551,-0.5991218... | 3,376 |
Calcium signaling pathway | 8 | 18 | 2.905785 | 0.003663 | P12235,Q9Y277,P21796,P45880,P16615,P12236,Q13555,Q08209 | Processes and pathways | KEGG Pathways | msigdb_kegg | 97,136,41,44,178,375,254,379 | 609,1785,97,375,178,1910,2005,3139,845,41,44,982,379,2012,254,407,1188,136 | 0.7669425203474032,-0.19815223757022424,2.2592655177971985,1.1865154018947937,1.7674589112604508,-0.2581525139593801,-0.3035420687482125,-1.1493665932391064,0.46616755845459307,2.8548455407684523,2.7903132643602064,0.3306972515746962,1.1745691139378525,-0.3035420687482125,1.5120884232445022,1.126554488303031,0.17816419... | 3,376 |
Biliary tract abnormality | 12 | 29 | 2.904881 | 0.003674 | P50542,P14174,Q10713,O43933,O95202,P09601,O43681,Q9NZJ7,Q14108,P04062,P07602,Q14739 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 286,481,388,513,358,9,137,173,147,118,469,347 | 137,513,358,2468,1698,118,469,9,481,2848,2432,2685,286,1358,753,388,1162,2834,147,347,585,1683,1047,1236,1026,173,1490,1155,781 | 1.9814208160018005,0.8933042921551931,1.222218044879942,-0.5673244671099098,-0.1535347647507937,2.1064111698932244,0.9925796692463879,3.508477031496731,0.9679086309299181,-0.8099606559026915,-0.535692346636734,-0.6955235731118161,1.3977418285889271,0.050492732938221645,0.5856054418382873,1.1625999707615722,0.1921878347... | 3,376 |
Golgi apparatus | 58 | 183 | 2.90305 | 0.003695 | Q8NC54,P67812,P09601,Q9H3P7,Q9HD26,Q9UG56,O60499,O00461,P80303,P16278,Q5VZ89,Q9UID3,Q8N4Q0,Q8IYS2,Q8NBN3,P50542,Q8NCH0,Q9NPR9,A1L0T0,Q96RQ1,Q9HC07,P50897,Q9NWM8,Q13190,Q5VW38,Q93050,Q6ZRP7,P98194,O15258,Q96K37,Q9H4A6,P05067,Q92520,Q8WVQ1,Q99576,O15260,Q8IXU6,O43760,Q99640,Q9H0U4,Q9NTJ5,Q02818,P04439,Q9NX62,Q9H2V7,O9507... | Localization | Protein Atlas Subcellular | protein_atlas_subcellular_location_all | 6,7,9,396,526,528,11,146,19,273,532,150,283,542,32,286,34,35,418,168,43,47,176,304,52,55,442,568,565,586,74,204,77,205,207,79,597,84,212,471,472,344,468,219,92,99,610,227,486,618,636,114,116,372,119,121,507,253 | 418,3003,2286,921,146,1811,1601,486,856,1055,565,79,1661,1189,3245,2124,3238,116,84,1840,11,121,2287,3150,1605,3163,1782,1534,1080,99,1057,468,204,3362,9,2127,1355,273,2357,2035,2147,2591,2407,3165,2293,949,1038,632,2265,2447,1915,2149,1916,610,286,965,1705,47,2449,1755,507,686,2471,1635,858,2810,7,19,938,568,2271,344,... | 1.0781682329246185,-0.9603410571851295,-0.45732323785786155,0.3852422065417807,1.939203453754038,-0.21309725685462735,-0.1092398235540067,0.9555364168366788,0.45275332185277023,0.2756661511961478,0.8177955706609692,2.4183608115792006,-0.13873418933689516,0.1641085471368729,-1.380679358108941,-0.364590575074656,-1.36256... | 3,376 |
Huntingtons disease | 17 | 80 | 2.89691 | 0.003769 | P12235,Q9UDW1,P13073,P14406,Q9Y277,P21796,P45880,P21912,P12236,O14949,O95168,O43676,Q9Y6M9,P00846,P20674,P00403,O96000 | Processes and pathways | KEGG Pathways | msigdb_kegg | 97,36,100,8,136,41,44,268,375,18,343,25,282,28,317,95,30 | 1903,1559,1243,18,2315,763,25,1603,1812,566,1324,1397,3020,343,1561,1326,2678,30,95,28,3335,2067,609,751,907,2288,2430,1909,97,375,100,8,2289,1175,2805,1143,3153,317,41,268,879,408,2948,3023,2240,3006,1264,2322,1209,981,2434,1704,44,2408,3271,3129,538,2410,2594,1435,2436,2010,2733,1919,2596,2012,1019,458,969,2837,2762,... | -0.2581525139593801,-0.07988664715431047,0.12174807413919582,3.3235076545102,-0.4729166554316845,0.5724477159799228,3.106682006127666,-0.1092398235540067,-0.21309725685462735,0.8177955706609692,0.06480999958601061,0.021757766555510514,-0.9772829358324227,1.245907190269227,-0.07988664715431047,0.06480999958601061,-0.695... | 3,376 |
Sphingolipid metabolism | 8 | 10 | 2.896438 | 0.003774 | Q06136,Q13510,Q16739,Q9NZ01,P04062,P07602,P17900,O95470 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 103,175,51,278,118,469,500,315 | 521,1781,315,118,469,500,103,175,51,278 | 0.8807829276640542,-0.19815223757022424,1.30474106378976,2.1064111698932244,0.9925796692463879,0.9182717672838793,2.2289873418727852,1.789183956579087,2.706377290804834,1.4322648574279548 | 3,376 |
Organophosphate ester transmembrane transporter activity | 6 | 13 | 2.873757 | 0.004056 | P12235,Q9BSK2,Q86VD7,Q6KCM7,Q9H2D1,Q8TB61 | Functions | GO Molecular function | msigdb_gomf | 97,3,72,76,15,112 | 1189,727,609,97,375,3078,76,679,72,112,3,15,193 | 0.1641085471368729,0.6118374126406803,0.7669425203474032,2.2592655177971985,1.1865154018947937,-1.0455292059601446,2.428173597886573,0.6769360722247575,2.457521700066298,2.1679949059006707,3.8868120422021692,3.349044243996922,1.72378323442192 | 3,376 |
Nucleotide transmembrane transporter activity | 6 | 13 | 2.873757 | 0.004056 | P12235,Q9BSK2,Q86VD7,Q6KCM7,Q9H2D1,Q8TB61 | Functions | GO Molecular function | msigdb_gomf | 97,3,72,76,15,112 | 1189,727,609,97,375,3078,76,679,72,112,3,15,193 | 0.1641085471368729,0.6118374126406803,0.7669425203474032,2.2592655177971985,1.1865154018947937,-1.0455292059601446,2.428173597886573,0.6769360722247575,2.457521700066298,2.1679949059006707,3.8868120422021692,3.349044243996922,1.72378323442192 | 3,376 |
secondary carrier transporter | 9 | 14 | 2.872133 | 0.004077 | Q9BQT8,Q96K37,O95202,O75746,Q8TB61,Q9UJS0,Q02978,Q8WWI5,Q9UBX3 | Functions | Panther Protein class | panther_protein_class | 475,586,358,489,112,437,594,573,59 | 489,358,1196,594,2253,112,573,586,475,1171,59,437,1257,726 | 0.9431396034941706,1.222218044879942,0.1641085471368729,0.7924210222267182,-0.42625550585234623,2.1679949059006707,0.8177955706609692,0.8051212350176506,0.9802563479044419,0.19218783473832943,2.6498026320516255,1.0538338490539432,0.12174807413919582,0.6249119037114952 | 3,376 |
Insertion of tail anchored proteins into the endoplasmic reticulum membrane | 8 | 12 | 2.871426 | 0.004086 | Q7L5D6,P09601,O43681,P05067,Q13190,P51648,P46379,P50402 | Processes and pathways | Reactome Pathways | msigdb_reactome | 296,9,137,204,304,80,409,220 | 137,1098,204,9,409,431,220,80,2968,304,296,2484 | 1.9814208160018005,0.23406828346498643,1.6798031111121596,3.508477031496731,1.1144929997983144,1.0538338490539432,1.6132522522142752,2.4183608115792006,-0.9097982049966251,1.3397781272483118,1.3630278999226435,-0.5673244671099098 | 3,376 |
Endoplasmic reticulum tubular network organization | 7 | 12 | 2.870215 | 0.004102 | Q9NQC3,Q9H6H4,Q8NHH9,P61026,P57088,O95197,Q6NUK4 | Processes and pathways | GO Biological process | msigdb_gobp | 66,261,134,495,470,29,415 | 29,470,495,508,909,415,134,1487,864,261,1774,66 | 3.0535407471601967,0.9925796692463879,0.9307180881219075,0.9058005368829619,0.39880353572925303,1.0902999671477054,1.991931331193204,-0.021598244629604746,0.45275332185277023,1.500746929971123,-0.1832436057353802,2.554385400886273 | 3,376 |
Macromolecule transmembrane transporter activity | 7 | 12 | 2.856671 | 0.004281 | O60830,Q9NS69,Q07820,Q99595,O96008,Q15388,O14925 | Functions | GO Molecular function | msigdb_gomf | 0,2,323,4,523,242,156 | 156,0,1325,523,610,966,1437,323,242,4,2,855 | 1.8860326867293702,3.918017746429074,0.06480999958601061,0.8807829276640542,0.7669425203474032,0.3443787137519083,0.007339737540638098,1.2930183954698358,1.5572509969346298,3.8081377581322435,3.918017746429074,0.46616755845459307 | 3,376 |
Sterol binding | 6 | 16 | 2.8555 | 0.004297 | Q14849,P21796,P45880,P30536,Q14108,P35610 | Functions | GO Molecular function | msigdb_gomf | 98,41,44,334,147,501 | 506,1373,2353,2207,41,2147,1429,334,501,44,1455,147,98,1112,2090,2229 | 0.9058005368829619,0.03614204326984603,-0.4885500586033537,-0.41078076891872717,2.8548455407684523,-0.37994850970962596,0.007339737540638098,1.2695070730093605,0.9182717672838793,2.7903132643602064,-0.007112210270966405,1.939203453754038,2.249188800352927,0.23406828346498643,-0.3339900772103585,-0.41078076891872717 | 3,376 |
oxidase | 6 | 13 | 2.853327 | 0.004326 | P13073,P14406,Q6ZRP7,O75880,P20674,Q15800 | Functions | Panther Protein class | panther_protein_class | 100,8,442,188,317,126 | 1243,602,1869,188,1909,100,8,1175,317,1211,126,442,1648 | 0.12174807413919582,0.779694821256333,-0.24309720612430855,1.7347305225090166,-0.2581525139593801,2.2390960928105765,3.549788972453769,0.17816419100440917,1.30474106378976,0.1500207496396212,2.0650208618258294,1.0416310057595912,-0.12396926881478841 | 3,376 |
Abnormality of head blood vessel | 12 | 24 | 2.852856 | 0.004333 | P21964,P06865,P10619,P03886,Q9NZJ7,P48651,Q9C0D9,Q13510,P16278,Q9Y4P3,P07602,P00846 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 159,386,132,68,173,141,239,175,273,279,469,28 | 1660,2123,28,68,386,469,2680,132,2497,273,500,159,949,141,2326,3111,175,697,2525,760,239,173,3117,279 | -0.13873418933689516,-0.364590575074656,3.0624281306689123,2.525480253725994,1.1625999707615722,0.9925796692463879,-0.6955235731118161,2.012900196950257,-0.5832023743822983,1.4437304908127628,0.9182717672838793,1.8646386144308038,0.35802993391519033,1.970892831816529,-0.4729166554316845,-1.0972246196014959,1.7891839565... | 3,376 |
Optic neuropathy | 7 | 23 | 2.851473 | 0.004352 | P03886,Q9NPL8,Q9P0J0,O43676,P00846,Q86Y39,O96000 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 68,232,93,25,28,62,30 | 25,1812,566,1324,30,28,68,3153,3006,1969,3129,1435,62,2219,2191,1926,562,2089,232,1254,2745,93,282 | 3.106682006127666,-0.21309725685462735,0.8177955706609692,0.06480999958601061,3.0446410783605184,3.0624281306689123,2.525480253725994,-1.1668478915554994,-0.9603410571851295,-0.2883747518392183,-1.1319358181488326,0.007339737540638098,2.62132664953133,-0.41078076891872717,-0.3953451725415673,-0.2581525139593801,0.83044... | 3,376 |
Steroid biosynthetic process | 15 | 46 | 2.849574 | 0.004378 | P00387,Q16850,Q14849,Q9H2C2,Q9H3P7,P11413,P37268,P16435,Q13510,P30536,P04035,Q15392,Q14534,Q14739,Q15800 | Processes and pathways | GO Biological process | msigdb_gobp | 321,65,98,104,396,393,238,456,175,334,251,87,153,347,126 | 578,1373,2353,321,251,707,393,802,2623,456,1013,2147,1429,2912,1245,334,238,1913,1194,1477,2995,3219,1269,175,3065,153,347,98,2664,87,1311,658,126,65,465,1022,2899,2195,1112,2987,2392,104,396,2347,779,2617 | 0.8051212350176506,0.03614204326984603,-0.4885500586033537,1.2930183954698358,1.5234094998830219,0.6379588946017836,1.1506078804869229,0.5195356321277029,-0.6632195009402341,1.017153527787551,0.3032430368863615,-0.37994850970962596,0.007339737540638098,-0.8596738042439521,0.12174807413919582,1.2695070730093605,1.568491... | 3,376 |
Secondary alcohol metabolic process | 16 | 41 | 2.847426 | 0.004407 | P00387,Q16850,Q14849,Q9H2C2,P11413,Q8WTV0,P05067,P16435,P37268,P04035,P04062,P35610,Q15392,Q14534,Q14739,Q15800 | Processes and pathways | GO Biological process | msigdb_gobp | 321,65,98,104,393,300,204,456,238,251,118,501,87,153,347,126 | 506,2316,1373,2865,2353,321,251,118,204,393,802,456,2912,501,238,1913,1194,3140,2008,3025,1477,2995,1455,2571,3219,1269,3065,153,347,98,1336,2664,87,658,126,65,300,3132,104,2347,2232 | 0.9058005368829619,-0.4729166554316845,0.03614204326984603,-0.8264864472557774,-0.4885500586033537,1.2930183954698358,1.5234094998830219,2.1064111698932244,1.6798031111121596,1.1506078804869229,0.5195356321277029,1.017153527787551,-0.8596738042439521,0.9182717672838793,1.5684911717900816,-0.2581525139593801,0.164108547... | 3,376 |
Establishment of protein localization to mitochondrial membrane | 10 | 17 | 2.844886 | 0.004443 | Q9NS69,Q53H12,Q9Y512,O14737,Q9Y5L4,Q9Y5J7,P30419,Q15070,Q9Y5J9,Q9P0J0 | Processes and pathways | GO Biological process | msigdb_gobp | 2,290,417,326,668,429,556,86,157,93 | 2286,326,1325,1701,1785,556,2806,86,290,733,2,93,1155,417,429,157,668 | -0.45732323785786155,1.281273760705501,0.06480999958601061,-0.1535347647507937,-0.19815223757022424,0.8304441394676204,-0.7770435603241972,2.369069040392317,1.386191839289798,0.6118374126406803,3.918017746429074,2.2793711942368797,0.20617963072146406,1.0902999671477054,1.0660128924007646,1.8860326867293702,0.6898742644... | 3,376 |
Intrinsic component of golgi membrane | 8 | 10 | 2.835247 | 0.004579 | O95070,Q9Y282,L0R6Q1,Q8TB61,O43505,Q969X5,Q6ZRP7,P98194 | Localization | GO Cellular component | msigdb_gocc | 99,75,333,112,553,311,442,568 | 333,565,553,99,568,1215,442,112,311,75 | 1.2695070730093605,0.8177955706609692,0.8304441394676204,2.2390960928105765,0.8177955706609692,0.1500207496396212,1.0416310057595912,2.1679949059006707,1.3281208444722734,2.437971309123152 | 3,376 |
ER-Golgi transport | 12 | 51 | 2.835142 | 0.004581 | O95070,O15027,Q96RQ1,P49257,Q15363,Q9Y282,P49069,Q9P2W9,Q969X5,O95249,O95197,Q9HCU5 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 99,486,168,331,73,75,431,22,311,88,29,350 | 1811,486,1602,1662,3238,2287,1533,1722,99,29,88,1844,1963,2239,2035,1038,1916,431,331,610,673,2471,1635,2326,1502,767,2366,1059,1310,2896,73,1089,2298,796,1108,2386,1798,1220,889,1764,311,168,2050,350,546,1078,22,1554,75,1229,1747 | -0.21309725685462735,0.9555364168366788,-0.1092398235540067,-0.13873418933689516,-1.362566906250655,-0.45732323785786155,-0.06526256357203314,-0.16837117607596028,2.2390960928105765,3.0535407471601967,2.32935923806442,-0.22807885031082178,-0.2883747518392183,-0.42625550585234623,-0.31874711143957013,0.28946999971654247... | 3,376 |
Intrinsic component of mitochondrial outer membrane | 8 | 14 | 2.832973 | 0.004612 | Q9BWH2,Q8TB36,O96008,Q15388,P50416,Q9GZY8,P57105,Q8IWA4 | Localization | GO Cellular component | msigdb_gocc | 196,258,523,242,307,373,313,605 | 1325,670,523,307,313,242,2478,605,927,1459,258,196,373,1419 | 0.06480999958601061,0.6769360722247575,0.8807829276640542,1.3281208444722734,1.3164418516370977,1.5572509969346298,-0.5673244671099098,0.779694821256333,0.3852422065417807,-0.007112210270966405,1.500746929971123,1.7128169189107314,1.1984389259522672,0.021757766555510514 | 3,376 |
Regulation of mitochondrion organization | 15 | 43 | 2.83237 | 0.00462 | P12235,Q9H3K2,Q96A26,O14737,P21796,Q9H4A6,Q9UG56,O60313,P30536,P30419,Q9GZY8,Q9Y6C9,O43464,O00165,Q99536 | Processes and pathways | GO Biological process | msigdb_gobp | 97,453,40,326,41,74,528,236,334,556,373,120,530,504,545 | 504,1054,326,530,236,1843,1698,1699,2067,609,2709,97,2682,41,2930,556,334,1913,1704,2685,1159,786,711,2215,1948,927,1459,1001,1073,40,2278,929,2942,545,373,453,74,1226,1628,833,528,2395,120 | 0.9058005368829619,0.2756661511961478,1.281273760705501,0.8682363372946176,1.5797113102117606,-0.22807885031082178,-0.1535347647507937,-0.1535347647507937,-0.3339900772103585,0.7669425203474032,-0.7117402486747223,2.2592655177971985,-0.6955235731118161,2.8548455407684523,-0.8763358915188677,0.8304441394676204,1.2695070... | 3,376 |
calmodulin-related | 6 | 14 | 2.827894 | 0.004686 | Q9BPX6,Q14257,O43852,P80303,Q02818,Q9BRK5 | Functions | Panther Protein class | panther_protein_class | 512,64,302,19,344,119 | 302,1785,2129,846,820,1307,19,344,64,1593,533,1741,512,119 | 1.3397781272483118,-0.19815223757022424,-0.364590575074656,0.46616755845459307,0.5062366837929436,0.07909400602166337,3.3064270469258985,1.245907190269227,2.592723326528482,-0.09454567529886222,0.8682363372946176,-0.16837117607596028,0.9058005368829619,2.1064111698932244 | 3,376 |
Abnormality of corneal stroma | 6 | 12 | 2.826411 | 0.004707 | P50542,P10619,O43933,Q13510,P16278,P04062 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 286,132,513,175,273,118 | 553,513,118,132,273,1965,1452,286,1564,175,1313,1053 | 0.8304441394676204,0.8933042921551931,2.1064111698932244,2.012900196950257,1.4437304908127628,-0.2883747518392183,-0.007112210270966405,1.3977418285889271,-0.07988664715431047,1.789183956579087,0.07909400602166337,0.28946999971654247 | 3,376 |
Incoordination | 29 | 72 | 2.815499 | 0.00487 | Q10713,O43681,P21912,Q9Y619,Q9NVV4,P00846,Q9NR77,Q01105,O95140,P53007,Q9NZJ7,Q13510,Q99707,O14773,Q13501,Q9UJX6,Q9Y5P6,P07602,O43819,P12235,Q6DKK2,Q05086,Q8TC12,O75503,P04062,O00165,Q9UBB4,P35670,Q15067 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 388,137,268,272,536,28,31,294,670,425,173,175,443,61,711,725,341,469,602,97,224,740,628,241,118,504,384,632,255 | 504,3284,2674,61,2123,1694,137,602,2491,2144,241,991,670,827,28,118,2206,469,3223,97,2003,268,1014,2322,1454,632,1634,794,1704,1016,2565,425,753,1852,3079,1818,2180,294,2919,740,2074,388,711,175,1820,2415,255,2836,1709,224,3322,1710,2875,1948,628,2793,929,1483,443,2987,1236,2744,1957,31,536,173,384,1899,1188,725,341,27... | 0.9058005368829619,-1.5648744215576544,-0.6955235731118161,2.62132664953133,-0.364590575074656,-0.1535347647507937,1.9814208160018005,0.779694821256333,-0.5832023743822983,-0.37994850970962596,1.5572509969346298,0.31698540656083257,0.6769360722247575,0.49290910856241765,3.0624281306689123,2.1064111698932244,-0.41078076... | 3,376 |
O acyltransferase activity | 8 | 14 | 2.814404 | 0.004887 | Q96N66,Q8NF37,P23786,Q92604,P50416,P35610,O15228,Q9HCL2 | Functions | GO Molecular function | msigdb_gomf | 225,332,265,663,307,501,529,27 | 529,265,2625,501,307,1621,689,332,663,225,986,27,1553,1468 | 0.8682363372946176,1.466599174519213,-0.6632195009402341,0.9182717672838793,1.3281208444722734,-0.1092398235540067,0.6639708590611185,1.281273760705501,0.6898742644114918,1.602091776312444,0.3306972515746962,3.097855519585872,-0.06526256357203314,-0.007112210270966405 | 3,376 |
Progressive gait ataxia | 8 | 13 | 2.813654 | 0.004898 | O43681,Q9NW15,Q9NZJ7,Q05086,Q9NVV4,P07602,P00846,O14773 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 137,234,173,740,536,469,28,61 | 61,1694,137,28,469,2003,753,1564,740,1483,536,234,173 | 2.62132664953133,-0.1535347647507937,1.9814208160018005,3.0624281306689123,0.9925796692463879,-0.3035420687482125,0.5856054418382873,-0.07988664715431047,0.5987352995655117,-0.021598244629604746,0.8682363372946176,1.5909114869453034,1.8000185178422223 | 3,376 |
Memory impairment | 10 | 39 | 2.812222 | 0.00492 | P03886,P49770,O43681,Q9NZJ7,P05067,Q9UJS0,P07602,Q9NZ08,P00403,Q9UNE7 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 68,514,137,173,204,437,469,314,95,319 | 137,523,95,68,204,469,2033,2652,1454,1704,1331,1126,514,1755,753,1564,1852,1539,2573,1920,1758,711,2078,2301,3143,1575,1927,1483,1466,314,173,1898,1867,437,319,1118,1718,1447,1296 | 1.9814208160018005,0.8807829276640542,2.2693262981715874,2.525480253725994,1.6798031111121596,0.9925796692463879,-0.31874711143957013,-0.6793500706356256,-0.007112210270966405,-0.1535347647507937,0.06480999958601061,0.22013973023415834,0.8933042921551931,-0.1832436057353802,0.5856054418382873,-0.07988664715431047,-0.22... | 3,376 |
Mitochondrial nucleotide transporter subfamily | 7 | 11 | 2.812103 | 0.004922 | P12235,Q9HC21,Q9BSK2,Q86VD7,Q6KCM7,Q9H2D1,Q70HW3 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 97,193,3,72,76,15,248 | 727,609,97,375,76,679,248,72,3,15,193 | 0.6118374126406803,0.7669425203474032,2.2592655177971985,1.1865154018947937,2.428173597886573,0.6769360722247575,1.5347102368011099,2.457521700066298,3.8868120422021692,3.349044243996922,1.72378323442192 | 3,376 |
Protein transmembrane transporter activity | 7 | 11 | 2.80707 | 0.004999 | O60830,Q9NS69,Q07820,Q99595,O96008,Q15388,O14925 | Functions | GO Molecular function | msigdb_gomf | 0,2,323,4,523,242,156 | 156,0,1325,523,610,1437,323,242,4,2,855 | 1.8860326867293702,3.918017746429074,0.06480999958601061,0.8807829276640542,0.7669425203474032,0.007339737540638098,1.2930183954698358,1.5572509969346298,3.8081377581322435,3.918017746429074,0.46616755845459307 | 3,376 |
Mental deterioration | 36 | 109 | 2.800415 | 0.005104 | P06865,Q10713,O43681,Q9UHD9,P21912,O96008,Q14108,P16278,O43464,P00846,P21964,Q9NZJ7,P50897,Q13510,Q8WWI5,O95470,O75306,Q9UNE7,P03886,Q5XKP0,P05067,O76024,P07602,P54802,P00403,Q96RL7,Q9H2C2,Q9NPL8,O60313,Q9Y487,O75503,P17900,P04062,O15118,Q9UBB4,Q08209 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 386,388,137,398,268,523,147,273,530,28,159,173,47,175,573,315,566,319,68,585,204,327,469,221,95,96,104,232,236,109,241,500,118,506,384,379 | 1054,506,530,137,602,236,3150,2491,566,241,327,670,2588,315,523,95,28,68,118,1158,204,386,469,2680,2033,1519,1846,3152,1303,273,3246,500,1965,1632,268,159,1101,2652,2322,1454,793,632,1498,2041,2913,1704,994,2629,47,2449,3303,753,221,1564,1852,1435,1455,2180,2596,1439,1145,2919,1282,2573,379,388,939,2367,711,175,147,969... | 0.2756661511961478,0.9058005368829619,0.8682363372946176,1.9814208160018005,0.779694821256333,1.5797113102117606,-1.1668478915554994,-0.5832023743822983,0.8177955706609692,1.5572509969346298,1.281273760705501,0.6769360722247575,-0.647131625751063,1.30474106378976,0.8807829276640542,2.2693262981715874,3.0624281306689123... | 3,376 |
metalloprotease | 8 | 27 | 2.794594 | 0.005196 | O75844,P42892,Q9BYT8,Q9UIQ6,Q7Z2K6,P55786,Q9NZ08,Q5JRX3 | Functions | Panther Protein class | panther_protein_class | 71,107,271,213,276,151,314,381 | 922,1905,71,1174,1699,2536,1752,879,3232,1209,107,1756,151,388,381,1339,276,617,2460,1484,1150,271,1956,1991,314,213,1296 | 0.3852422065417807,-0.2581525139593801,2.457521700066298,0.17816419100440917,-0.1535347647507937,-0.6150830158119736,-0.1832436057353802,0.42583726441943925,-1.344508871789742,0.1500207496396212,2.2087214952641787,-0.1832436057353802,1.9179887298526617,1.1625999707615722,1.1745691139378525,0.06480999958601061,1.4322648... | 3,376 |
Sphingolipid metabolism overview | 7 | 9 | 2.794463 | 0.005199 | Q96G23,Q06136,O15121,Q13510,Q16739,Q9NRA0,O95470 | Processes and pathways | WikiPathways | msigdb_wp | 163,103,105,175,51,407,315 | 105,521,1781,315,103,175,51,163,407 | 2.21886249397109,0.8807829276640542,-0.19815223757022424,1.30474106378976,2.2289873418727852,1.789183956579087,2.706377290804834,1.8431719091236531,1.126554488303031 | 3,376 |
Sphingolipid metabolism integrated pathway | 7 | 9 | 2.794463 | 0.005199 | Q96G23,Q06136,O15121,Q13510,Q16739,Q9NRA0,O95470 | Processes and pathways | WikiPathways | msigdb_wp | 163,103,105,175,51,407,315 | 105,521,1781,315,103,175,51,163,407 | 2.21886249397109,0.8807829276640542,-0.19815223757022424,1.30474106378976,2.2289873418727852,1.789183956579087,2.706377290804834,1.8431719091236531,1.126554488303031 | 3,376 |
Primary mitochondrial disease | 37 | 102 | 2.793989 | 0.005206 | Q96I36,Q9BUB7,Q9Y2R0,O14949,Q6P4A7,O43676,Q9Y6M9,P00846,Q53H12,Q96CU9,Q7KZN9,Q9UBX3,O75880,P20674,Q86Y39,O75306,Q8NI60,Q9NYY8,P03886,Q5XKP0,Q9BRT2,O75208,Q8NFF5,O43819,Q15526,Q9P0J0,P00403,Q9BQT8,P12235,Q07021,Q6DKK2,P13073,Q9NPL8,O60313,O95831,Q70HW3,P09001 | Drugs and Diseases | Protein Atlas Disease involvement | protein_atlas_disease_involvement | 517,645,10,18,152,25,282,28,290,562,572,59,188,317,62,566,452,589,68,585,714,455,722,602,731,93,95,475,97,729,224,100,232,236,362,248,631 | 1559,18,25,1603,602,236,455,1812,566,1324,1749,188,1326,362,95,28,68,2681,907,631,97,100,2289,3153,317,879,3023,3006,2322,2913,1969,2408,2364,3129,1538,3241,2130,753,1435,1456,2787,1919,729,1641,731,1822,290,996,3300,585,224,152,248,572,2816,62,1165,2219,722,452,1926,3202,1046,562,2024,517,2742,953,1863,1483,1150,2960,... | -0.07988664715431047,3.3235076545102,3.106682006127666,-0.1092398235540067,0.779694821256333,1.5797113102117606,1.017153527787551,-0.21309725685462735,0.8177955706609692,0.06480999958601061,-0.1832436057353802,1.7347305225090166,0.06480999958601061,1.21033977687557,2.2693262981715874,3.0624281306689123,2.52548025372599... | 3,376 |
Cellular monovalent inorganic cation homeostasis | 13 | 25 | 2.783465 | 0.005378 | Q9HC07,Q9Y487,P05023,Q9Y6M7,P50897,Q05086,Q92544,O75503,Q8N511,Q15904,Q93050,P06576,P61421 | Processes and pathways | GO Biological process | msigdb_gobp | 43,109,707,726,47,740,435,241,83,595,55,751,655 | 241,991,707,993,751,818,2175,2006,47,2072,2131,1196,655,740,595,83,435,55,1685,43,1188,1350,109,3037,726 | 1.5572509969346298,0.31698540656083257,0.6379588946017836,0.31698540656083257,0.5856054418382873,0.5062366837929436,-0.3953451725415673,-0.3035420687482125,2.743817956942605,-0.3339900772103585,-0.364590575074656,0.1641085471368729,0.6898742644114918,0.5987352995655117,0.7924210222267182,2.3986898186378873,1.0538338490... | 3,376 |
golgi | 26 | 65 | 2.772718 | 0.005559 | P61019,Q9Y3E0,Q9NR31,Q8NBN3,Q15836,Q13190,P53367,Q5VW38,O15258,Q96K37,Q9Y5P4,O14735,O15126,Q8IXU6,Q9H0U4,Q15904,Q9NTJ5,Q9H2M9,O15127,P49755,Q9Y487,Q8WVM8,P61026,Q9Y371,P53365,Q8IZA0 | Localization | OpenCell Localization | opencell_localization | 767,547,546,32,559,304,686,52,565,586,842,448,579,597,471,595,472,864,856,610,109,889,495,638,507,253 | 1811,448,2513,1601,579,856,565,1605,991,1722,1934,2288,2430,2239,1453,2147,1038,1498,2447,610,507,686,1635,2326,1502,767,495,2366,1059,2596,1794,1540,304,1271,1089,2298,559,595,52,2082,2386,597,253,1220,32,889,1460,972,586,2090,471,864,1465,546,472,2484,1554,1389,1690,638,547,919,109,842,1747 | -0.21309725685462735,1.0294042647856594,-0.599121814464143,-0.1092398235540067,0.8051212350176506,0.45275332185277023,0.8177955706609692,-0.1092398235540067,0.31698540656083257,-0.16837117607596028,-0.27324496497470774,-0.45732323785786155,-0.535692346636734,-0.42625550585234623,-0.007112210270966405,-0.379948509709625... | 3,376 |
Lipid biosynthetic process | 65 | 146 | 2.759724 | 0.005785 | Q10713,Q9P035,P11802,Q9H3P7,Q9UG56,Q9NXE4,P48651,O15269,P11413,Q92604,Q15738,Q92643,Q9NZ01,O15228,Q9NPH0,Q14534,Q9HCL2,Q86YN1,Q86SK9,Q9NRA0,Q53H12,Q96G23,Q9NVV0,Q8NCC3,Q9BYI3,Q99805,P09455,Q13510,Q8WTV0,Q16739,Q8WWI5,Q14457,O95470,O95749,Q16850,P00387,O14735,Q8NF37,Q8NBX0,O14734,P30536,P16435,Q9H7Z7,Q53GQ0,Q8WXW3,Q9NTJ... | Processes and pathways | GO Biological process | msigdb_gobp | 388,266,648,396,528,667,141,521,393,663,658,277,278,529,24,153,27,154,280,407,290,163,170,689,692,46,174,175,300,51,573,440,315,316,65,321,448,332,462,578,334,456,599,465,466,472,87,216,219,347,351,481,98,225,104,103,105,369,238,239,501,118,630,251,126 | 738,1297,2202,3367,960,578,448,105,529,521,1781,630,2062,1373,2865,2263,2353,315,1587,316,2707,1099,321,251,118,1845,707,2680,174,393,648,481,802,2623,3296,456,2804,1013,2147,1429,2912,3188,2653,1245,334,896,501,897,238,775,1913,1194,141,1126,2008,1477,2995,1614,3308,3219,1794,103,388,3371,1269,175,3065,440,153,347,98,... | 0.5987352995655117,0.07909400602166337,-0.41078076891872717,-4.151705872762363,0.3443787137519083,0.8051212350176506,1.0294042647856594,2.21886249397109,0.8682363372946176,0.8807829276640542,-0.19815223757022424,0.7285278893546684,-0.3339900772103585,0.03614204326984603,-0.8264864472557774,-0.44176959203476396,-0.48855... | 3,376 |
Visual loss | 22 | 47 | 2.750947 | 0.005942 | P51798,Q10713,P53701,P00846,P40939,O95140,Q15051,Q9NZJ7,P50897,Q8IY17,O14773,O75306,P03886,P04439,P07602,O15460,P00403,O60313,Q8TC12,O75503,Q96JJ3,P54098 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 640,388,142,28,794,670,805,173,47,700,61,566,68,468,469,590,95,236,628,241,377,753 | 2557,801,1054,61,590,236,566,1905,241,1011,670,95,3061,28,68,2825,468,469,2517,2319,3172,1497,2431,794,1194,47,1358,640,1128,142,753,2210,2271,388,2330,1920,3287,2477,805,700,628,1764,1927,377,2987,1254,173 | -0.631086208801837,0.5195356321277029,0.2756661511961478,2.62132664953133,0.7924210222267182,1.5797113102117606,0.8177955706609692,-0.2581525139593801,1.5572509969346298,0.3032430368863615,0.6769360722247575,2.2693262981715874,-1.0283952575793793,3.0624281306689123,2.525480253725994,-0.7934797786581159,0.99257966924638... | 3,376 |
mitochondria | 8 | 11 | 2.749096 | 0.005976 | Q9NVH1,Q9Y277,P21796,P45880,Q969Q5,Q15388,Q9NR31,Q8IWA4 | Localization | OpenCell Localization | opencell_localization | 483,136,41,44,16,242,546,605 | 1325,670,41,44,1923,242,605,16,546,483,136 | 0.06480999958601061,0.6769360722247575,2.8548455407684523,2.7903132643602064,-0.2581525139593801,1.5572509969346298,0.779694821256333,3.3405432490399405,0.8556644142476869,0.9679086309299181,1.991931331193204 | 3,376 |
Retrograde vesicle mediated transport golgi to endoplasmic reticulum | 8 | 28 | 2.746697 | 0.00602 | O15258,Q96RQ1,Q9H4A6,Q9Y282,Q8TD16,Q9H9E3,Q9P2W9,Q969X5 | Processes and pathways | GO Biological process | msigdb_gobp | 565,168,74,75,372,187,22,311 | 1811,565,1533,2239,2035,1038,1704,1916,2243,610,1635,2366,938,1310,2246,1108,372,889,1460,311,1074,168,74,187,1078,22,1554,75 | -0.21309725685462735,0.8177955706609692,-0.06526256357203314,-0.42625550585234623,-0.31874711143957013,0.28946999971654247,-0.1535347647507937,-0.2581525139593801,-0.42625550585234623,0.7669425203474032,-0.12396926881478841,-0.4885500586033537,0.3716510518956005,0.07909400602166337,-0.42625550585234623,0.23406828346498... | 3,376 |
Phospholipid metabolic process | 31 | 77 | 2.740401 | 0.006136 | Q10713,Q9Y263,Q9UG56,Q9NXE4,P48651,O15269,Q92604,Q92643,Q9NRA0,O15228,Q9NPH0,Q86YN1,Q9HCL2,Q9NVV0,Q96DA6,Q8NCC3,Q9BYI3,Q8WTV0,Q8WWI5,Q14457,Q96S52,O95749,O14735,Q8NF37,Q9NTJ5,Q96PE3,Q9NX62,Q96N66,P37268,Q9C0D9,Q8NHP8 | Processes and pathways | GO Biological process | msigdb_gobp | 388,646,528,667,141,521,663,277,407,529,24,154,27,170,563,689,692,300,573,440,702,316,448,332,472,216,219,225,238,239,115 | 2886,2202,448,529,521,1781,2062,2865,1587,316,2707,2680,802,2804,3139,2147,2625,897,238,794,1793,141,3303,2995,3219,1794,388,3065,440,2664,1457,1621,154,700,2156,689,1737,332,115,300,1763,1575,573,663,277,900,1480,563,225,216,702,1549,892,986,1114,3369,810,1387,692,2229,239,916,27,24,1203,407,472,1553,170,219,667,2484,... | -0.8430574101429883,-0.41078076891872717,1.0294042647856594,0.8682363372946176,0.8807829276640542,-0.19815223757022424,-0.3339900772103585,-0.8264864472557774,-0.09454567529886222,1.30474106378976,-0.7117402486747223,-0.6955235731118161,0.5195356321277029,-0.7770435603241972,-1.1493665932391064,-0.37994850970962596,-0.... | 3,376 |
Alcohol metabolic process | 26 | 82 | 2.733454 | 0.006267 | Q10713,P11413,Q8NBN7,Q6NUM9,Q9NRA0,Q14534,Q8WTV0,Q13510,Q16850,P00387,P05067,P16435,P51648,Q15392,Q96PE3,Q14739,Q9NX62,Q9Y394,Q14849,Q9H2C2,P37268,P35610,P04062,O15118,P04035,Q15800 | Processes and pathways | GO Biological process | msigdb_gobp | 388,393,274,405,407,153,300,175,65,321,204,456,80,87,216,347,219,228,98,104,238,501,118,506,251,126 | 2886,506,521,1781,2316,2062,1373,2865,2263,2353,2707,764,321,251,118,204,2169,1519,393,1964,802,2355,2623,456,2826,1013,2912,2562,2755,501,238,1913,633,1194,3140,2008,3025,2449,3303,80,1477,2995,3168,937,1455,2571,967,3219,1794,388,1269,175,2331,3065,153,347,98,1336,2664,87,658,126,1507,65,2953,405,274,628,300,216,2942... | -0.8430574101429883,0.9058005368829619,0.8807829276640542,-0.19815223757022424,-0.4729166554316845,-0.3339900772103585,0.03614204326984603,-0.8264864472557774,-0.44176959203476396,-0.4885500586033537,-0.7117402486747223,0.5724477159799228,1.2930183954698358,1.5234094998830219,2.1064111698932244,1.6798031111121596,-0.39... | 3,376 |
Nuclear bodies | 30 | 130 | 2.579083 | 0.009906 | O75153,Q9UQ84,Q16637,Q9H9B1,Q9H993,Q96RL1,Q92994,Q8IXH7,Q9BTY7,P09132,Q9Y4E8,P52788,O75695,Q15345,P33240,Q9Y4C2,P20585,Q96MF7,O95248,Q8NEM2,P15927,Q8IYQ7,Q9BXW9,Q92889,Q14457,Q13867,P56282,Q96FJ2,Q8WYQ5,Q15554 | Localization | Protein Atlas Subcellular | protein_atlas_subcellular_location_all | 6,8,144,146,286,283,419,307,37,40,449,299,57,64,192,338,191,329,75,465,82,326,358,356,225,460,95,109,385,125 | 1719,663,1720,769,1569,2398,1102,1313,621,6,2703,1924,57,952,1501,75,2092,2315,2851,40,1653,1111,82,1115,1193,191,1868,2945,2990,192,1391,732,2592,1994,2854,553,2741,299,2221,95,2492,900,2662,1747,1336,2598,2456,1810,1592,2110,3175,1218,460,2165,2556,225,1886,1946,2917,493,64,688,125,850,144,2331,1062,1684,2230,2880,25... | -0.044067709882776376,0.5112695688752548,-0.044067709882776376,0.44109416141745744,0.024568563594607476,-0.4509476953948541,0.2665828304056785,0.16252714442340316,0.5464352780067219,5.668921347145836,-0.7508459131023316,-0.14658317757621844,2.1032963978654777,0.3362265384392549,0.05897311520212943,1.9550615206595165,-0... | 3,205 |
Cellular response to vascular endothelial growth factor stimulus | 6 | 8 | 2.097844 | 0.035919 | Q16539,Q12948,Q96E22,P04083,P04792,P23634 | Processes and pathways | GO Biological process | msigdb_gobp | 496,223,536,70,9,22 | 1720,70,9,22,223,557,496,536 | -0.044067709882776376,1.992059338814486,5.308362296900556,3.311292975041059,1.1158699245679418,0.6169209415124207,0.687609972296476,0.6522402054291618 | 3,205 |
Regulation of lysosomal lumen ph | 6 | 7 | 2.365115 | 0.018024 | O75503,Q9HC07,O75787,Q9NWW5,P50897,Q8N511 | Processes and pathways | GO Biological process | msigdb_gobp | 128,289,290,235,41,16 | 128,290,41,16,406,289,235 | 1.9093648873212545,1.0835998439422212,3.2418655988469802,4.159089053264923,0.8274975960490513,1.1029433898907732,1.2937201610174092 | 3,210 |
Dysostosis multiplex | 6 | 7 | 2.365115 | 0.018024 | P16278,P10619,O00754,P15586,P04066,P54802 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 131,38,198,246,284,125 | 198,284,38,246,131,125,406 | 1.4429978380230684,1.1029433898907732,3.315858403774397,1.2179808768128926,1.8919256615910303,1.9441300559071935,0.8274975960490513 | 3,210 |
transmembrane signal receptor | 7 | 8 | 2.30665 | 0.021074 | Q9NZT2,O75787,O15173,Q99720,O00264,Q9UMX5,P15260 | Functions | Panther Protein class | panther_protein_class | 294,290,229,10,137,172,15 | 137,229,290,15,434,10,294,172 | 1.8217862056621752,1.2937201610174092,1.0835998439422212,4.239282271600796,0.7671267334341764,4.4887817989782315,1.0835998439422212,1.6075749697690414 | 3,210 |
Sphingolipid metabolism | 6 | 10 | 2.302038 | 0.021333 | Q16739,Q13510,P04062,P07602,P17900,Q06136 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 32,75,47,48,111,90 | 422,2652,141,47,48,111,90,75,32,1057 | 0.7873051138665256,-0.6847656636079493,1.8041546249047102,3.076843619635619,3.031288546754357,2.081710348546229,2.3170155929508804,2.4485152075098346,3.432969472681017,0.20004755229564355 | 3,210 |
Vacuolar acidification | 6 | 10 | 2.183956 | 0.028965 | Q93050,O75503,Q9NWW5,P50897,Q8N511,Q9Y487 | Processes and pathways | GO Biological process | msigdb_gobp | 64,128,235,41,16,150 | 128,290,41,2180,16,64,235,1549,150,2683 | 1.9093648873212545,1.0835998439422212,3.2418655988469802,-0.36894409591271893,4.159089053264923,2.673764653157473,1.2937201610174092,-0.06723513363812487,1.7687738657447782,-0.6847656636079493 | 3,210 |
calmodulin-related | 7 | 10 | 2.148088 | 0.031707 | P80303,Q9BPX6,Q02818,Q8IYU8,Q14257,Q9BRK5,O43852 | Functions | Panther Protein class | panther_protein_class | 4,133,13,207,84,247,340 | 340,1754,378,4,13,84,2633,207,133,247 | 0.9270379483271718,-0.1817089841565943,0.847512453464809,5.1520987989651195,4.345144496536938,2.3500868340317056,-0.6599314453348567,1.405947875030295,1.8919256615910303,1.2179808768128926 | 3,210 |
Sphingolipid metabolism in senescence | 9 | 12 | 2.135112 | 0.032752 | Q16739,O15121,P16278,Q96G23,Q13510,P04062,P24941,P11802,Q06136 | Processes and pathways | WikiPathways | msigdb_wp | 32,97,131,136,75,47,305,342,90 | 97,422,47,342,131,305,902,933,90,75,32,136 | 2.2337520122835284,0.7873051138665256,3.076843619635619,0.9270379483271718,1.8919256615910303,1.0252702855408282,0.2869328465936709,0.26531099795843516,2.3170155929508804,2.4485152075098346,3.432969472681017,1.8393788820543948 | 3,210 |
Membrane lipid catabolic process | 7 | 11 | 2.128993 | 0.033255 | P50897,Q13510,O95470,P04062,P17900,P06280,Q99735 | Processes and pathways | GO Biological process | msigdb_gobp | 41,75,141,47,111,245,255 | 141,47,284,245,900,2659,111,41,75,255,2196 | 1.8041546249047102,3.076843619635619,1.1029433898907732,1.2179808768128926,0.2869328465936709,-0.6847656636079493,2.081710348546229,3.2418655988469802,2.4485152075098346,1.1989282768348137,-0.36894409591271893 | 3,210 |
Bulbar signs | 7 | 12 | 2.09055 | 0.036568 | P35637,Q9Y263,Q99720,P04062,P03886,P07602,P06753 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 414,456,10,47,14,48,399 | 442,14,47,399,48,1805,414,1294,1486,10,1021,456 | 0.746893082576532,4.239282271600796,3.076843619635619,0.8274975960490513,3.031288546754357,-0.2048342170031588,0.8074286080916745,0.04537661015180214,-0.044566305353490585,4.4887817989782315,0.22186887095956295,0.746893082576532 | 3,210 |
Nonalcoholic fatty liver disease | 22 | 48 | 4.161549 | 0.000032 | P21912,P22695,P51970,O95298,Q9P0J0,P60953,O43676,P15954,O14949,P14406,Q9UDW1,O75380,P49840,P63000,P31040,O00217,P31930,Q86Y39,O95299,P20674,O75251,P00403 | Processes and pathways | WikiPathways | msigdb_wp | 496,129,499,256,14,270,36,414,43,44,46,434,187,438,211,92,218,233,475,495,493,366 | 92,668,1528,43,36,1710,493,822,434,1768,256,475,366,1906,1197,714,1352,786,44,523,2304,414,1040,495,496,129,1783,211,2895,218,2355,1426,1916,614,187,902,499,1297,270,438,1672,2277,1059,233,2064,14,46,1346 | 1.9517715396466142,0.5034926557472869,-0.013762661187869209,2.768680735877916,3.0612894149232734,-0.0997257723165647,0.6764533068474775,0.3883303529448472,0.7630278449071122,-0.1283651722112755,1.1388686667807886,0.7053046416328677,0.8785548612321639,-0.18562193543010477,0.1583723191033171,0.47469099999317105,0.0722693... | 3,210 |
Electron transport | 21 | 47 | 4.066161 | 0.000048 | P21912,Q9H3N1,P51970,P22695,O95298,Q9P0J0,Q16134,O43169,O43676,O14949,Q9UDW1,O75380,O95864,P31040,O00217,P31930,Q86Y39,Q99757,O95299,O75251,P00403 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 496,264,499,129,256,14,391,145,36,43,46,434,195,211,92,218,233,360,475,493,366 | 92,668,43,145,1897,36,1710,493,822,434,1768,256,475,195,366,1350,1197,1145,2304,1040,496,497,129,1783,211,218,1596,1295,1426,614,499,1297,391,2277,1059,2772,1942,233,2851,2242,360,1017,264,14,46,2338,1346 | 1.9517715396466142,0.5034926557472869,2.768680735877916,1.5738113969759262,-0.18562193543010477,3.0612894149232734,-0.0997257723165647,0.6764533068474775,0.3883303529448472,0.7630278449071122,-0.1283651722112755,1.1388686667807886,0.7053046416328677,1.3416792792210046,0.8785548612321639,0.07226934763416325,0.1583723191... | 3,210 |
Abnormality of the mitochondrion | 37 | 98 | 3.968965 | 0.000072 | P21912,P26358,P51970,Q9Y4W6,P22570,Q9BUB7,O43772,Q4J6C6,O95298,Q9UMS0,Q9P0J0,Q16134,Q8IUX1,Q9Y584,Q08426,O43676,Q969Y2,P49748,Q70HW3,O75380,Q00325,O60783,Q9UBX3,P31040,O00217,Q86SX6,P46976,Q86Y39,Q99757,O95299,Q9H845,P12235,P40939,P49821,P20674,O75251,P00403 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 496,498,499,400,497,536,9,10,256,399,14,391,531,25,29,36,177,174,58,434,556,433,73,211,92,623,219,233,360,475,381,114,613,614,495,493,366 | 92,1894,668,36,9,433,493,822,434,1768,2348,256,475,366,1350,785,980,1199,1716,3111,114,786,1145,1040,495,496,497,679,498,1783,983,211,2617,2465,1295,613,1484,1597,219,174,614,1668,2410,499,2411,1733,1545,869,1297,1494,556,29,1434,2159,1618,391,1059,2771,2980,1215,2718,10,2629,2719,1376,58,2377,654,623,233,531,3144,1261... | 1.9517715396466142,-0.18562193543010477,0.5034926557472869,3.0612894149232734,4.471263356608017,0.7630278449071122,0.6764533068474775,0.3883303529448472,0.7630278449071122,-0.1283651722112755,-0.4143647846958465,1.1388686667807886,0.7053046416328677,0.8785548612321639,0.07226934763416325,0.41710978314444397,0.273288737... | 3,210 |
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