term
stringlengths
2
121
overlap
int64
6
281
setsize
int64
7
499
score
float64
1.96
10.6
pval
float64
0
0.05
edge
stringlengths
41
1.97k
type
stringclasses
5 values
subtype
stringclasses
24 values
subtype_key
stringclasses
24 values
edge_idxs
stringlengths
11
1.17k
ann_idxs
stringlengths
19
2.31k
ann_vals
stringlengths
124
9.94k
sig_size
int64
2.2k
3.73k
Large ribosomal subunit
27
75
2.328196
0.019902
P51116,Q9H2W6,P61254,P18077,Q9BYC9,P30050,P61513,P47914,Q9BYD1,P42766,P50914,Q96A35,Q9Y3U8,P83881,P49207,Q96GC5,P62750,P62917,Q07020,P62910,Q6P1L8,P62888,P61353,Q9P015,P39023,P46776,P61927
Localization
GO Cellular component
msigdb_gocc
259,396,6,257,538,388,139,269,189,554,312,62,471,204,579,207,580,581,482,220,356,618,617,384,612,240,122
3100,2760,2205,1473,257,2462,746,1419,828,388,1481,749,1725,612,2098,554,240,867,751,641,269,579,2546,312,259,2411,6,1049,617,139,122,1491,580,1609,618,1302,2468,220,2869,581,793,1611,204,905,1930,2583,482,870,2768,2223,2687,356,2630,2326,1379,62,3104,2118,207,960,538,189,814,1449,2248,396,1516,1390,1391,2937,2639,1337,384,2187,471
-1.6370929036029538,-0.7566787356245731,-0.32863839725396865,0.014906920281284118,1.1388686667807886,-0.5000305276776785,0.4458966875052482,0.043584231076383116,0.3883303529448472,0.8496631638098913,0.014906920281284118,0.4458966875052482,-0.0997257723165647,0.5611177432905115,-0.2714529942827711,0.6187714535547078,1.1967846271462892,0.35955846414598713,0.4458966875052482,0.532301591048701,1.1099198375930281,0.5899410509488118,-0.557108085715093,0.9941865778088491,1.1388686667807886,-0.4429266939583211,4.736544775086076,0.24454771184920537,0.5611177432905115,1.602853122792676,1.7190744805634337,0.014906920281284118,0.5899410509488118,-0.042424588305331204,0.5611177432905115,0.10096234789685095,-0.5000305276776785,1.254724699862172,-0.8990449194071448,0.5899410509488118,0.41710978314444397,-0.042424588305331204,1.3126885452713448,0.33079418522630977,-0.18562193543010477,-0.585637146978094,0.7053046416328677,0.35955846414598713,-0.7566787356245731,-0.32863839725396865,-0.6711860899363502,0.9074531014169275,-0.614159800319998,-0.38579613781079947,0.07226934763416325,2.4473153810696386,-1.6654091771450312,-0.2714529942827711,1.3126885452713448,0.3020375859379114,0.6476088916672819,1.399678167637441,0.41710978314444397,0.043584231076383116,-0.32863839725396865,0.8496631638098913,0.014906920281284118,0.07226934763416325,0.07226934763416325,-1.0128317515561631,-0.614159800319998,0.10096234789685095,0.8785548612321639,-0.30004918409410347,0.7341628395132606
3,210
Metalloendopeptidase activity
6
15
2.324053
0.020123
P22695,Q10713,P78536,Q5JRX3,O75844,P42892
Functions
GO Molecular function
msigdb_gomf
129,159,168,100,294,212
1582,2399,294,1658,129,212,2038,168,159,100,2447,2330,595,916,400
-0.042424588305331204,-0.4429266939583211,1.0231104921518903,-0.07107893462425983,1.660952980636015,1.2837036718300274,-0.24284976542710374,1.4867194622568927,1.5157445302511974,1.8644711387133321,-0.4714819228517013,-0.38579613781079947,0.5899410509488118,0.33079418522630977,0.8496631638098913
3,210
Lactic acidosis
30
90
2.319094
0.02039
P51970,Q9BUB7,O75879,Q4J6C6,Q9UMS0,Q8IUX1,P14854,O43676,Q10713,Q969Y2,Q6P4A7,Q70HW3,O75380,Q00325,Q99797,O60783,P12694,Q9HC21,P31040,O00217,Q8NI60,Q86Y39,O95299,Q5XKP0,Q9NP80,Q9H845,P12235,P40939,O75251,P00403
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
499,536,255,10,399,531,523,36,159,177,299,58,434,556,595,433,574,349,211,92,102,233,475,377,514,381,114,613,493,366
92,1894,668,36,2459,433,493,822,434,1768,255,475,366,1350,2501,2570,1414,2614,785,1197,980,1199,1716,2538,895,114,574,523,1040,1783,211,2266,613,1484,1597,1426,1917,3196,614,499,1733,1157,1297,2846,556,794,159,1797,2771,1798,2718,10,1375,2629,2049,2719,377,299,58,950,233,531,3144,2960,102,1261,177,2851,1634,595,1570,768,536,2487,1120,381,349,514,3155,1339,1889,2491,1820,399,1460,1760,2339,2135,1188,1346
1.9517715396466142,-0.18562193543010477,0.5034926557472869,3.0612894149232734,-0.5000305276776785,0.7630278449071122,0.6764533068474775,0.3883303529448472,0.7630278449071122,-0.1283651722112755,1.1388686667807886,0.7053046416328677,0.8785548612321639,0.07226934763416325,-0.5285725638095914,-0.585637146978094,0.043584231076383116,-0.614159800319998,0.41710978314444397,0.1583723191033171,0.27328873734257736,0.1583723191033171,-0.0997257723165647,-0.557108085715093,0.33079418522630977,1.7772173493984713,0.5899410509488118,0.6476088916672819,0.24454771184920537,-0.1283651722112755,1.2837036718300274,-0.3572206950736908,0.5611177432905115,0.014906920281284118,-0.042424588305331204,0.043584231076383116,-0.18562193543010477,-3.4405571683800065,0.5611177432905115,0.6764533068474775,-0.0997257723165647,0.1870894267741931,0.10096234789685095,-0.8705836214377505,0.6187714535547078,0.41710978314444397,1.5157445302511974,-0.1283651722112755,-0.7566787356245731,-0.1283651722112755,-0.6996898275229555,4.353447366494844,0.07226934763416325,-0.614159800319998,-0.24284976542710374,-0.6996898275229555,0.8785548612321639,1.0231104921518903,2.5057048530603376,0.3020375859379114,1.2257516709181544,0.6476088916672819,-2.1178248450474757,-1.06969074968926,1.8644711387133321,0.12966331135686696,1.4577000206031279,-0.8705836214377505,-0.042424588305331204,0.5899410509488118,-0.013762661187869209,0.4458966875052482,0.6476088916672819,-0.5000305276776785,0.21581458325266947,0.8785548612321639,0.9363578339004853,0.6764533068474775,-2.258966469671713,0.10096234789685095,-0.15699720383151142,-0.5000305276776785,-0.1283651722112755,0.8496631638098913,0.043584231076383116,-0.0997257723165647,-0.38579613781079947,-0.2714529942827711,0.1870894267741931,0.10096234789685095
3,210
Respiratory chain complex iv
8
11
2.309981
0.020889
P22695,P15954,P14406,P20674,P14854,P09669,O00483,P00403
Localization
GO Cellular component
msigdb_gocc
129,414,44,495,523,714,668,366
668,366,714,1352,786,44,523,414,495,129,1426
0.5034926557472869,0.8785548612321639,0.47469099999317105,0.07226934763416325,0.41710978314444397,2.768680735877916,0.6476088916672819,0.7918996031387205,0.6764533068474775,1.660952980636015,0.043584231076383116
3,210
ribosomal protein
41
124
2.299157
0.021496
Q9Y2Q9,Q9H2W6,P61254,P18077,Q9BYC9,P46779,P30050,P47914,P62263,P62753,P62273,Q9UHA3,Q9BYD1,P42766,P50914,Q96A35,O60783,Q9Y3U8,P63220,P83881,P49207,P82912,Q96GC5,P62750,P62917,Q07020,P46776,P62910,Q6P1L8,P62888,P61353,P62857,P55769,P82914,O76021,P39023,Q9P015,P25398,P61247,P61927,P15880
Functions
Panther Protein class
panther_protein_class
265,396,6,257,538,641,388,269,152,290,40,568,189,554,312,62,433,471,203,204,579,78,207,580,581,482,240,220,356,618,617,253,110,372,607,612,384,119,616,122,368
433,607,3100,2760,2205,1588,979,1473,368,257,2462,746,2866,119,1419,828,388,1481,749,1725,866,612,2098,716,554,240,867,751,641,1485,642,2309,269,579,2546,312,1669,2411,110,991,616,6,1049,617,122,2766,1364,1209,2102,152,792,2897,40,1490,3020,1491,1210,580,290,1609,1927,904,2362,253,618,1302,2468,220,2869,581,793,203,1851,1494,2513,1366,78,372,2846,2899,1611,204,905,1930,2583,482,870,2768,2476,2321,2687,356,2630,2326,1113,1379,1263,1628,62,2118,207,960,538,189,814,1449,2248,396,1390,1391,2937,2295,2639,1020,384,568,971,265,1025,1760,2187,2135,2458,471
0.7630278449071122,0.5611177432905115,-1.6370929036029538,-0.7566787356245731,-0.32863839725396865,-0.042424588305331204,0.27328873734257736,0.014906920281284118,0.8785548612321639,1.1388686667807886,-0.5000305276776785,0.4458966875052482,-0.8990449194071448,1.7481432606681047,0.043584231076383116,0.3883303529448472,0.8496631638098913,0.014906920281284118,0.4458966875052482,-0.0997257723165647,0.35955846414598713,0.5611177432905115,-0.2714529942827711,0.47469099999317105,0.6187714535547078,1.1967846271462892,0.35955846414598713,0.4458966875052482,0.532301591048701,0.014906920281284118,0.532301591048701,-0.38579613781079947,1.1099198375930281,0.5899410509488118,-0.557108085715093,0.9941865778088491,-0.07107893462425983,-0.4429266939583211,1.806296713684594,0.27328873734257736,0.5611177432905115,4.736544775086076,0.24454771184920537,0.5611177432905115,1.7190744805634337,-0.7566787356245731,0.07226934763416325,0.1583723191033171,-0.2714529942827711,1.5447751873907711,0.41710978314444397,-0.9559499207681041,2.8856731513793363,0.014906920281284118,-1.2401339859422156,0.014906920281284118,0.1583723191033171,0.5899410509488118,1.0520407045954674,-0.042424588305331204,-0.18562193543010477,0.33079418522630977,-0.4143647846958465,1.1678236113059064,0.5611177432905115,0.10096234789685095,-0.5000305276776785,1.254724699862172,-0.8990449194071448,0.5899410509488118,0.41710978314444397,1.3126885452713448,-0.15699720383151142,0.014906920281284118,-0.5285725638095914,0.07226934763416325,2.1556490854488635,0.8785548612321639,-0.8705836214377505,-0.9559499207681041,-0.042424588305331204,1.3126885452713448,0.33079418522630977,-0.18562193543010477,-0.585637146978094,0.7053046416328677,0.35955846414598713,-0.7566787356245731,-0.5000305276776785,-0.38579613781079947,-0.6711860899363502,0.9074531014169275,-0.614159800319998,-0.38579613781079947,0.21581458325266947,0.07226934763416325,0.12966331135686696,-0.042424588305331204,2.4473153810696386,-0.2714529942827711,1.3126885452713448,0.3020375859379114,0.6476088916672819,1.399678167637441,0.41710978314444397,0.043584231076383116,-0.32863839725396865,0.8496631638098913,0.07226934763416325,0.07226934763416325,-1.0128317515561631,-0.3572206950736908,-0.614159800319998,0.27328873734257736,0.8785548612321639,0.6187714535547078,0.3020375859379114,1.1388686667807886,0.27328873734257736,-0.0997257723165647,-0.30004918409410347,-0.2714529942827711,-0.4714819228517013,0.7341628395132606
3,210
Cellular response to starvation
41
92
2.2824
0.022466
P35268,P46778,P61254,P18077,P84098,P46779,P30050,P61513,P47914,P46782,P62263,P62753,P62273,P62266,P63173,P42766,Q92616,P50914,Q9Y3U8,P63220,P83881,P49207,P27635,P62750,P62917,P20042,Q07020,P42677,P46776,P62910,P62888,P61353,P62857,P39019,P46777,P39023,P25398,P61247,P61927,P15880,P18621
Processes and pathways
Reactome Pathways
msigdb_reactome
749,751,6,257,905,641,388,139,269,642,152,290,40,792,793,554,850,312,471,203,204,579,828,580,581,341,482,716,240,220,618,617,253,866,867,612,119,616,122,368,746
1906,3100,2760,2205,978,1588,979,368,257,2462,746,341,2264,2940,2866,119,1419,828,388,1481,749,2097,1725,1663,866,612,2098,1203,1204,716,554,240,867,751,641,1485,642,2309,269,579,312,991,616,6,1049,617,2412,139,122,2766,1364,1209,2102,152,792,2897,40,1490,3020,1491,1210,580,290,1609,1927,904,2362,253,2581,618,1302,2468,220,2869,581,793,203,1611,204,905,1930,2583,482,2552,956,2116,850,2483,1891,2604,471,2824
-0.18562193543010477,-1.6370929036029538,-0.7566787356245731,-0.32863839725396865,0.27328873734257736,-0.042424588305331204,0.27328873734257736,0.8785548612321639,1.1388686667807886,-0.5000305276776785,0.4458966875052482,0.9363578339004853,-0.3572206950736908,-1.0412640839639304,-0.8990449194071448,1.7481432606681047,0.043584231076383116,0.3883303529448472,0.8496631638098913,0.014906920281284118,0.4458966875052482,-0.2714529942827711,-0.0997257723165647,-0.07107893462425983,0.35955846414598713,0.5611177432905115,-0.2714529942827711,0.1583723191033171,0.1583723191033171,0.47469099999317105,0.6187714535547078,1.1967846271462892,0.35955846414598713,0.4458966875052482,0.532301591048701,0.014906920281284118,0.532301591048701,-0.38579613781079947,1.1099198375930281,0.5899410509488118,0.9941865778088491,0.27328873734257736,0.5611177432905115,4.736544775086076,0.24454771184920537,0.5611177432905115,-0.4429266939583211,1.602853122792676,1.7190744805634337,-0.7566787356245731,0.07226934763416325,0.1583723191033171,-0.2714529942827711,1.5447751873907711,0.41710978314444397,-0.9559499207681041,2.8856731513793363,0.014906920281284118,-1.2401339859422156,0.014906920281284118,0.1583723191033171,0.5899410509488118,1.0520407045954674,-0.042424588305331204,-0.18562193543010477,0.33079418522630977,-0.4143647846958465,1.1678236113059064,-0.585637146978094,0.5611177432905115,0.10096234789685095,-0.5000305276776785,1.254724699862172,-0.8990449194071448,0.5899410509488118,0.41710978314444397,1.3126885452713448,-0.042424588305331204,1.3126885452713448,0.33079418522630977,-0.18562193543010477,-0.585637146978094,0.7053046416328677,-0.557108085715093,0.3020375859379114,-0.2714529942827711,0.3883303529448472,-0.5000305276776785,-0.15699720383151142,-0.585637146978094,0.7341628395132606,-0.8136432086046264
3,210
Organelle inner membrane
77
240
2.281616
0.022512
P21912,Q69YU5,P51970,Q99595,P22570,Q9BUB7,O43772,Q9BYC9,Q9P0J0,Q9UG56,Q02127,Q9H2D1,Q8IUX1,P14854,Q15070,Q9Y584,Q9Y6C9,Q99720,O43676,O14949,P14406,Q9UDW1,Q9H9P8,Q9BUR5,Q9Y619,Q70HW3,Q96A35,Q9UBX3,P22830,P82912,Q9UDX5,O00217,Q14728,Q8NI60,P12235,P04818,P22695,Q5SNT2,Q9Y5J9,Q10713,P49748,Q9BYD1,Q8TAA5,Q96GC5,P31040,Q14739,Q8IXM6,P31930,Q86Y39,Q8NBN7,Q9Y2Q9,O95298,Q6P4A7,O75844,Q9NRK6,Q8WWC4,Q9HC21,Q9H3K2,Q6P1L8,P53701,Q5XKP0,Q9H845,Q9P015,P82914,P50402,P00403,Q9Y4W6,Q9H2W6,Q16134,P15954,Q9BQT8,O75380,O60783,P36551,O95299,P20674,O75251
Localization
GO Cellular component
msigdb_gocc
496,1,499,0,497,536,9,538,14,543,15,16,531,523,22,25,26,34,36,43,44,46,50,48,57,58,62,73,77,78,80,92,95,102,114,125,129,131,137,159,174,189,188,207,211,222,224,218,233,235,265,256,299,294,319,318,349,361,356,354,377,381,384,372,370,366,400,396,391,414,446,434,433,460,475,495,493
92,668,1463,43,521,36,9,2459,1710,1085,433,929,493,822,434,890,2399,1768,2756,1769,1088,294,2348,2201,1836,1348,1140,256,475,2988,2828,1470,366,1350,125,784,1840,1351,1091,1197,1473,2503,714,1352,2537,114,2539,825,786,44,523,2304,414,2092,1040,495,1982,496,497,129,77,2866,679,1289,1986,1783,211,218,899,1786,1044,460,2212,613,1484,1913,2684,1426,3048,2546,174,614,2438,370,1669,499,2411,2653,354,1363,1157,791,555,1297,1050,1610,1851,1494,2513,1366,78,372,2846,2899,556,15,795,2584,159,1615,870,839,2768,1369,1497,2223,95,222,22,391,2277,1059,1504,1215,1375,131,1000,377,1,1942,728,356,299,1002,1801,588,2774,58,2377,2630,2326,233,531,224,3064,3144,2634,2593,1379,235,1067,3032,764,1170,102,188,732,318,1263,1628,62,3045,2851,3104,2288,2118,852,207,3182,1633,2330,0,1327,34,2747,1693,446,960,3141,1950,768,536,48,538,189,814,1449,2248,1017,16,736,396,361,381,1755,2489,1516,50,968,349,1390,1391,3155,2937,319,2128,1456,2822,2639,1182,1337,384,1339,14,73,46,80,543,1022,1820,1821,2338,1460,971,265,2457,1025,1760,1761,2340,2187,2135,2458,400,1027,25,137,57,26,1346
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3,210
Sulfur compound transport
8
12
2.275539
0.022874
Q8TB61,Q9UBX3,O15439,Q9H0H5,O00400,Q9HC21,Q70HW3,P33527
Processes and pathways
GO Biological process
msigdb_gobp
169,73,13,274,321,349,58,151
321,1896,13,367,151,3187,795,58,169,274,349,73
0.9652690090027104,-0.18562193543010477,3.9415276975615496,0.8785548612321639,1.5447751873907711,-2.906871317124417,0.41710978314444397,2.5057048530603376,1.4867194622568927,1.1099198375930281,0.9363578339004853,2.243098964599965
3,210
Selenoamino acid metabolism
44
93
2.272213
0.023074
P35268,P46778,P61254,P18077,P84098,P62847,P46779,P30050,P61513,P47914,P46782,O43324,P62263,P62753,P62273,P62266,P63173,P42766,P50914,P23526,Q9Y3U8,P63220,P83881,P49207,P27635,P00390,P62750,P62917,Q07020,P42677,P46776,P62910,P57772,P62888,P61353,P62857,P39019,P46777,P39023,P25398,P61247,P61927,P15880,P18621
Processes and pathways
Reactome Pathways
msigdb_reactome
749,751,6,257,905,904,641,388,139,269,642,519,152,290,40,792,793,554,312,678,471,203,204,579,828,324,580,581,482,716,240,220,721,618,617,253,866,867,612,119,616,122,368,746
2939,519,324,3100,2760,2205,1090,1588,979,1979,368,257,2462,746,2866,678,119,1419,828,388,3124,1481,749,1725,866,612,2098,1787,716,554,240,867,751,641,1485,642,2309,2036,269,579,1206,312,903,1996,721,991,616,6,1049,617,139,122,2766,1364,1209,2102,152,792,2897,40,1490,3020,1491,1210,580,290,1609,1927,904,2362,253,2581,618,1302,2468,220,2869,581,793,203,1611,204,905,1930,2583,482,2440,3031,1618,2772,2385,1889,471
-1.0412640839639304,0.6476088916672819,0.9652690090027104,-1.6370929036029538,-0.7566787356245731,-0.32863839725396865,0.21581458325266947,-0.042424588305331204,0.27328873734257736,-0.21423943402394552,0.8785548612321639,1.1388686667807886,-0.5000305276776785,0.4458966875052482,-0.8990449194071448,0.5034926557472869,1.7481432606681047,0.043584231076383116,0.3883303529448472,0.8496631638098913,-1.8917659617484948,0.014906920281284118,0.4458966875052482,-0.0997257723165647,0.35955846414598713,0.5611177432905115,-0.2714529942827711,-0.1283651722112755,0.47469099999317105,0.6187714535547078,1.1967846271462892,0.35955846414598713,0.4458966875052482,0.532301591048701,0.014906920281284118,0.532301591048701,-0.38579613781079947,-0.24284976542710374,1.1099198375930281,0.5899410509488118,0.1583723191033171,0.9941865778088491,0.33079418522630977,-0.21423943402394552,0.47469099999317105,0.27328873734257736,0.5611177432905115,4.736544775086076,0.24454771184920537,0.5611177432905115,1.602853122792676,1.7190744805634337,-0.7566787356245731,0.07226934763416325,0.1583723191033171,-0.2714529942827711,1.5447751873907711,0.41710978314444397,-0.9559499207681041,2.8856731513793363,0.014906920281284118,-1.2401339859422156,0.014906920281284118,0.1583723191033171,0.5899410509488118,1.0520407045954674,-0.042424588305331204,-0.18562193543010477,0.33079418522630977,-0.4143647846958465,1.1678236113059064,-0.585637146978094,0.5611177432905115,0.10096234789685095,-0.5000305276776785,1.254724699862172,-0.8990449194071448,0.5899410509488118,0.41710978314444397,1.3126885452713448,-0.042424588305331204,1.3126885452713448,0.33079418522630977,-0.18562193543010477,-0.585637146978094,0.7053046416328677,-0.4714819228517013,-1.2685220944449345,-0.042424588305331204,-0.7566787356245731,-0.4143647846958465,-0.15699720383151142,0.7341628395132606
3,210
Regulation of epithelial cell migration
11
45
2.270276
0.023191
O75122,Q96E22,P78536,P23634,P42785,P61586,Q92766,Q8WTV0,O94813,Q9NQC3,P09601
Processes and pathways
GO Biological process
msigdb_gobp
65,336,168,70,76,229,445,19,118,285,239
1895,65,1239,118,2609,2204,1286,1840,1975,2650,1474,239,1659,2989,2913,70,1986,2542,1724,1204,76,2868,1298,1734,229,2845,438,2469,168,2367,1311,727,1313,802,803,19,445,336,2288,1753,3090,285,1274,1646,1647
-0.18562193543010477,2.4181275560384297,0.12966331135686696,1.7481432606681047,-0.614159800319998,-0.32863839725396865,0.10096234789685095,-0.15699720383151142,-0.21423943402394552,-0.6426760976202697,0.014906920281284118,1.1967846271462892,-0.07107893462425983,-1.1549371513670597,-0.9843937111343767,2.3014229202036454,-0.21423943402394552,-0.557108085715093,-0.0997257723165647,0.1583723191033171,2.184794201475348,-0.8990449194071448,0.10096234789685095,-0.0997257723165647,1.2257516709181544,-0.8705836214377505,0.7630278449071122,-0.5000305276776785,1.4867194622568927,-0.4143647846958465,0.10096234789685095,0.47469099999317105,0.10096234789685095,0.41710978314444397,0.41710978314444397,3.7358312584387403,0.7630278449071122,0.9652690090027104,-0.3572206950736908,-0.0997257723165647,-1.4954371449930277,1.0809771684172826,0.12966331135686696,-0.042424588305331204,-0.042424588305331204
3,210
Ribosomal proteins
44
130
2.269115
0.023261
Q9Y2Q9,Q9H2W6,P61254,P18077,Q9BYC9,P46779,P30050,P61513,P47914,P62263,P62753,P62273,Q9UHA3,O95478,Q9BYD1,P42766,P50914,Q96A35,O60783,Q9Y3U8,P63220,P83881,P49207,P82912,Q96GC5,P62750,P62917,Q07020,P46776,P62910,Q6P1L8,P62888,P61353,P62857,P55769,P82914,O76021,P39023,Q9P015,P63244,P25398,P61247,P61927,P15880
Functions
Protein Atlas Protein class
protein_atlas_protein_class
265,396,6,257,538,641,388,139,269,152,290,40,568,550,189,554,312,62,433,471,203,204,579,78,207,580,581,482,240,220,356,618,617,253,110,372,607,612,384,242,119,616,122,368
433,607,550,3100,2760,2205,1588,979,1473,368,257,2462,746,2866,119,1419,828,388,1481,749,1725,866,612,2098,716,554,240,867,751,641,1485,642,2309,269,579,2546,312,1669,2411,110,991,616,6,1049,617,139,122,2766,1364,1209,2102,152,792,2897,40,1490,3020,1491,1210,580,290,1609,1927,904,2362,253,618,1302,2468,220,2869,581,793,203,242,1851,1494,2513,1366,78,372,2846,2899,1611,204,905,1930,2583,482,870,2768,2223,2687,356,2630,2326,1379,910,1263,1628,62,3104,2118,852,207,538,189,814,1449,2248,396,1516,1390,1391,2937,2295,2639,1020,1337,384,568,1184,971,265,1025,1760,2187,2135,2458,471
0.7630278449071122,0.5611177432905115,0.6187714535547078,-1.6370929036029538,-0.7566787356245731,-0.32863839725396865,-0.042424588305331204,0.27328873734257736,0.014906920281284118,0.8785548612321639,1.1388686667807886,-0.5000305276776785,0.4458966875052482,-0.8990449194071448,1.7481432606681047,0.043584231076383116,0.3883303529448472,0.8496631638098913,0.014906920281284118,0.4458966875052482,-0.0997257723165647,0.35955846414598713,0.5611177432905115,-0.2714529942827711,0.47469099999317105,0.6187714535547078,1.1967846271462892,0.35955846414598713,0.4458966875052482,0.532301591048701,0.014906920281284118,0.532301591048701,-0.38579613781079947,1.1099198375930281,0.5899410509488118,-0.557108085715093,0.9941865778088491,-0.07107893462425983,-0.4429266939583211,1.806296713684594,0.27328873734257736,0.5611177432905115,4.736544775086076,0.24454771184920537,0.5611177432905115,1.602853122792676,1.7190744805634337,-0.7566787356245731,0.07226934763416325,0.1583723191033171,-0.2714529942827711,1.5447751873907711,0.41710978314444397,-0.9559499207681041,2.8856731513793363,0.014906920281284118,-1.2401339859422156,0.014906920281284118,0.1583723191033171,0.5899410509488118,1.0520407045954674,-0.042424588305331204,-0.18562193543010477,0.33079418522630977,-0.4143647846958465,1.1678236113059064,0.5611177432905115,0.10096234789685095,-0.5000305276776785,1.254724699862172,-0.8990449194071448,0.5899410509488118,0.41710978314444397,1.3126885452713448,1.1967846271462892,-0.15699720383151142,0.014906920281284118,-0.5285725638095914,0.07226934763416325,2.1556490854488635,0.8785548612321639,-0.8705836214377505,-0.9559499207681041,-0.042424588305331204,1.3126885452713448,0.33079418522630977,-0.18562193543010477,-0.585637146978094,0.7053046416328677,0.35955846414598713,-0.7566787356245731,-0.32863839725396865,-0.6711860899363502,0.9074531014169275,-0.614159800319998,-0.38579613781079947,0.07226934763416325,0.33079418522630977,0.12966331135686696,-0.042424588305331204,2.4473153810696386,-1.6654091771450312,-0.2714529942827711,0.3883303529448472,1.3126885452713448,0.6476088916672819,1.399678167637441,0.41710978314444397,0.043584231076383116,-0.32863839725396865,0.8496631638098913,0.014906920281284118,0.07226934763416325,0.07226934763416325,-1.0128317515561631,-0.3572206950736908,-0.614159800319998,0.27328873734257736,0.10096234789685095,0.8785548612321639,0.6187714535547078,0.1870894267741931,0.3020375859379114,1.1388686667807886,0.27328873734257736,-0.0997257723165647,-0.30004918409410347,-0.2714529942827711,-0.4714819228517013,0.7341628395132606
3,210
Dermal atrophy
7
27
2.265774
0.023465
Q8NCH0,Q9NWM8,Q15392,Q9H1A4,P22413,O75844,O00170
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
163,35,68,275,47,294,124
124,1193,294,1970,1532,639,1842,2865,1095,1535,47,1043,1722,715,1849,354,1855,1859,726,757,68,163,3142,533,275,35,1761
1.6900110425777688,0.1583723191033171,1.0231104921518903,-0.21423943402394552,-0.013762661187869209,0.532301591048701,-0.15699720383151142,-0.8990449194071448,0.21581458325266947,-0.013762661187869209,2.6809820839637393,0.24454771184920537,-0.0997257723165647,0.47469099999317105,-0.15699720383151142,0.9074531014169275,-0.15699720383151142,-0.15699720383151142,0.47469099999317105,0.4458966875052482,2.3305920279943764,1.5157445302511974,-2.0895832987920526,0.6476088916672819,1.1099198375930281,3.1198615395312252,-0.0997257723165647
3,210
Muscle adaptation
8
18
2.265574
0.023477
P25490,Q9Y5B0,P23634,P58546,Q14457,P16615,P09601,P49840
Processes and pathways
GO Biological process
msigdb_gobp
478,103,70,138,231,386,239,187
2757,712,1532,239,1035,2884,386,70,478,187,138,502,2517,2108,1794,1437,231,103
-0.7566787356245731,0.47469099999317105,-0.013762661187869209,1.1967846271462892,0.24454771184920537,-0.9275003379149459,0.8496631638098913,2.3014229202036454,0.7053046416328677,1.399678167637441,1.602853122792676,0.6764533068474775,-0.5285725638095914,-0.2714529942827711,-0.1283651722112755,0.043584231076383116,1.2257516709181544,1.8644711387133321
3,210
Organic acid transport
15
45
2.265045
0.02351
O14678,P08195,P53985,P08183,O43772,Q9UBX3,O15439,Q6P4A7,Q9H2D1,Q9BQT8,Q9NP80,Q9H2J7,Q9Y619,P33527,P50416
Processes and pathways
GO Biological process
msigdb_gobp
309,121,480,7,9,73,13,299,16,446,514,512,57,151,526
309,1896,13,9,605,546,1088,2892,2261,824,2204,894,1090,7,121,896,2913,679,1292,2969,2030,2895,935,151,3187,526,2653,480,942,795,2770,2280,299,729,1633,446,16,512,1755,2489,514,73,1820,3123,57
0.9941865778088491,-0.18562193543010477,3.9415276975615496,4.471263356608017,0.5611177432905115,0.6187714535547078,0.21581458325266947,-0.9559499207681041,-0.3572206950736908,0.3883303529448472,-0.32863839725396865,0.33079418522630977,0.21581458325266947,4.7070559039511,1.7190744805634337,0.33079418522630977,-0.9843937111343767,0.5034926557472869,0.10096234789685095,-1.0981117894775352,-0.24284976542710374,-0.9559499207681041,0.3020375859379114,1.5447751873907711,-2.906871317124417,0.6476088916672819,-0.6426760976202697,0.7053046416328677,0.3020375859379114,0.41710978314444397,-0.7566787356245731,-0.3572206950736908,1.0231104921518903,0.47469099999317105,-0.042424588305331204,0.7630278449071122,3.7945832692876573,0.6764533068474775,-0.0997257723165647,-0.5000305276776785,0.6764533068474775,2.243098964599965,-0.1283651722112755,-1.8634879482962017,2.534906450453798
3,210
Ventricular arrhythmia
11
35
2.255536
0.0241
O60783,P00403,O43772,Q96AX1,Q969Y2,P49748,P36551,P12235,P42892,P50402,P46976
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
433,366,9,508,177,174,460,114,212,370,219
9,433,822,2260,366,1532,1350,2649,1714,1589,1475,114,1659,1147,1590,496,679,460,936,3121,212,219,174,1155,2438,370,2318,1249,1114,3008,849,177,508,1875,1950
4.471263356608017,0.7630278449071122,0.3883303529448472,-0.3572206950736908,0.8785548612321639,-0.013762661187869209,0.07226934763416325,-0.6426760976202697,-0.0997257723165647,-0.042424588305331204,0.014906920281284118,1.7772173493984713,-0.07107893462425983,0.1870894267741931,-0.042424588305331204,0.6764533068474775,0.5034926557472869,0.7341628395132606,0.3020375859379114,-1.8634879482962017,1.2837036718300274,1.254724699862172,1.4577000206031279,0.1870894267741931,-0.4714819228517013,0.8785548612321639,-0.38579613781079947,0.12966331135686696,0.21581458325266947,-1.2117404843314936,0.3883303529448472,1.4577000206031279,0.6764533068474775,-0.15699720383151142,-0.18562193543010477
3,210
Dehydrogenase
16
59
2.231369
0.025657
P21912,Q8TC12,Q8N4Q0,Q8NCN5,Q00796,Q8N8N7,Q9P0J0,Q02127,Q9H9P8,P40925,P00390,Q14914,P31040,O00217,O75251,P11766
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
496,302,197,75,329,141,14,15,50,296,324,86,211,92,493,494
92,2197,1408,493,822,2828,2681,1285,324,1350,1587,1142,1351,980,2884,494,1353,496,2028,1783,576,787,211,2464,296,1664,2684,643,3196,682,790,499,940,832,1363,1297,329,15,1367,1369,86,1059,2772,1861,3070,197,141,75,764,302,2794,2851,1634,50,1953,970,817,14,2562
1.9517715396466142,-0.32863839725396865,0.043584231076383116,0.6764533068474775,0.3883303529448472,-0.8421163995463957,-0.6711860899363502,0.10096234789685095,0.9652690090027104,0.07226934763416325,-0.042424588305331204,0.1870894267741931,0.07226934763416325,0.27328873734257736,-0.9275003379149459,0.6764533068474775,0.07226934763416325,0.6764533068474775,-0.24284976542710374,-0.1283651722112755,0.5899410509488118,0.41710978314444397,1.2837036718300274,-0.5000305276776785,1.0231104921518903,-0.07107893462425983,-0.6711860899363502,0.532301591048701,-3.4405571683800065,0.5034926557472869,0.41710978314444397,0.6764533068474775,0.3020375859379114,0.3883303529448472,0.07226934763416325,0.10096234789685095,0.9652690090027104,3.82396482645708,0.07226934763416325,0.07226934763416325,2.0682431353184825,0.24454771184920537,-0.7566787356245731,-0.15699720383151142,-1.3820213293616825,1.3416792792210046,1.602853122792676,2.2139441703853113,0.4458966875052482,1.0231104921518903,-0.78516400280081,-0.8705836214377505,-0.042424588305331204,2.6809820839637393,-0.18562193543010477,0.3020375859379114,0.41710978314444397,3.9121315146567643,-0.557108085715093
3,210
Ire1alpha activates chaperones
8
26
2.22309
0.02621
Q969H8,Q9NWM8,O76024,O14773,P49748,P43307,P49840,O43909
Processes and pathways
Reactome Pathways
msigdb_reactome
423,35,350,267,174,85,187,432
267,432,350,893,1411,1532,1472,2544,85,174,187,2467,2412,1612,2930,2110,2550,1165,1066,423,565,35,1341,1829,1830,1345
1.1099198375930281,0.7630278449071122,0.9074531014169275,0.33079418522630977,0.043584231076383116,-0.013762661187869209,0.014906920281284118,-0.557108085715093,2.0682431353184825,1.4577000206031279,1.399678167637441,-0.5000305276776785,-0.4429266939583211,-0.042424588305331204,-1.0128317515561631,-0.2714529942827711,-0.557108085715093,0.1870894267741931,0.24454771184920537,0.7918996031387205,0.6187714535547078,3.1198615395312252,0.10096234789685095,-0.1283651722112755,-0.1283651722112755,0.10096234789685095
3,210
Ribosomal protein
55
123
2.212373
0.026941
Q9Y2Q9,P35268,P46778,Q9H2W6,P61254,P18077,P84098,Q9BYC9,P46779,P30050,P61513,P47914,P46782,Q9BYD2,P62263,P62753,P62273,P62266,P63173,Q9BYD1,P42766,P50914,Q96A35,O60783,Q96EY7,Q9Y3U8,P63220,P83881,P49207,P82912,Q96GC5,P27635,P62750,P62917,Q8TAE8,Q07020,P42677,P46776,P62910,Q6P1L8,P62888,P61353,P62857,P82914,P39019,P46777,P39023,Q9P015,P63244,P25398,P61247,Q13084,P61927,P15880,P18621
Functions
Protein Atlas Molecular function
protein_atlas_molecular_function
265,749,751,396,6,257,905,538,641,388,139,269,642,814,152,290,40,792,793,189,554,312,62,433,852,471,203,204,579,78,207,828,580,581,910,482,716,240,220,356,618,617,253,372,866,867,612,384,242,119,616,870,122,368,746
433,3100,2760,2205,1588,979,1473,368,257,2462,746,2866,119,1419,828,388,1481,749,1725,866,612,2098,716,554,240,867,751,641,1485,642,2309,269,579,2546,312,1669,2411,991,616,6,1049,617,139,122,2766,1364,1209,2102,152,792,2897,40,1490,3020,1491,1210,580,290,1609,1927,904,2362,253,618,1302,2468,220,2869,581,793,203,242,1851,1494,2513,1366,78,372,2846,2899,1611,204,905,1930,2583,482,870,2768,2223,2687,356,2630,2326,1379,910,1263,1628,62,3104,2118,852,207,538,189,814,1449,2248,396,1516,1390,1391,2937,2639,1337,384,971,265,1025,1760,2187,2135,2458,471
0.7630278449071122,-1.6370929036029538,-0.7566787356245731,-0.32863839725396865,-0.042424588305331204,0.27328873734257736,0.014906920281284118,0.8785548612321639,1.1388686667807886,-0.5000305276776785,0.4458966875052482,-0.8990449194071448,1.7481432606681047,0.043584231076383116,0.3883303529448472,0.8496631638098913,0.014906920281284118,0.4458966875052482,-0.0997257723165647,0.35955846414598713,0.5611177432905115,-0.2714529942827711,0.47469099999317105,0.6187714535547078,1.1967846271462892,0.35955846414598713,0.4458966875052482,0.532301591048701,0.014906920281284118,0.532301591048701,-0.38579613781079947,1.1099198375930281,0.5899410509488118,-0.557108085715093,0.9941865778088491,-0.07107893462425983,-0.4429266939583211,0.27328873734257736,0.5611177432905115,4.736544775086076,0.24454771184920537,0.5611177432905115,1.602853122792676,1.7190744805634337,-0.7566787356245731,0.07226934763416325,0.1583723191033171,-0.2714529942827711,1.5447751873907711,0.41710978314444397,-0.9559499207681041,2.8856731513793363,0.014906920281284118,-1.2401339859422156,0.014906920281284118,0.1583723191033171,0.5899410509488118,1.0520407045954674,-0.042424588305331204,-0.18562193543010477,0.33079418522630977,-0.4143647846958465,1.1678236113059064,0.5611177432905115,0.10096234789685095,-0.5000305276776785,1.254724699862172,-0.8990449194071448,0.5899410509488118,0.41710978314444397,1.3126885452713448,1.1967846271462892,-0.15699720383151142,0.014906920281284118,-0.5285725638095914,0.07226934763416325,2.1556490854488635,0.8785548612321639,-0.8705836214377505,-0.9559499207681041,-0.042424588305331204,1.3126885452713448,0.33079418522630977,-0.18562193543010477,-0.585637146978094,0.7053046416328677,0.35955846414598713,-0.7566787356245731,-0.32863839725396865,-0.6711860899363502,0.9074531014169275,-0.614159800319998,-0.38579613781079947,0.07226934763416325,0.33079418522630977,0.12966331135686696,-0.042424588305331204,2.4473153810696386,-1.6654091771450312,-0.2714529942827711,0.3883303529448472,1.3126885452713448,0.6476088916672819,1.399678167637441,0.41710978314444397,0.043584231076383116,-0.32863839725396865,0.8496631638098913,0.014906920281284118,0.07226934763416325,0.07226934763416325,-1.0128317515561631,-0.614159800319998,0.10096234789685095,0.8785548612321639,0.3020375859379114,1.1388686667807886,0.27328873734257736,-0.0997257723165647,-0.30004918409410347,-0.2714529942827711,-0.4714819228517013,0.7341628395132606
3,210
Negative regulation of growth
6
30
2.209174
0.027163
Q9Y5B0,Q9P0J0,P22413,P63244,O94813,P49840
Processes and pathways
GO Biological process
msigdb_gobp
103,14,47,242,118,187
1134,1968,1768,118,712,639,2145,2864,2884,47,478,2574,1786,187,1731,939,242,1212,2848,2318,1252,2775,1562,2116,1744,2288,285,14,1705,103
0.1870894267741931,-0.21423943402394552,-0.1283651722112755,1.7481432606681047,0.47469099999317105,0.532301591048701,-0.30004918409410347,-0.8990449194071448,-0.9275003379149459,2.6809820839637393,0.7053046416328677,-0.585637146978094,-0.1283651722112755,1.399678167637441,-0.0997257723165647,0.3020375859379114,1.1967846271462892,0.1583723191033171,-0.8705836214377505,-0.38579613781079947,0.12966331135686696,-0.7566787356245731,-0.013762661187869209,-0.2714529942827711,-0.0997257723165647,-0.3572206950736908,1.0809771684172826,3.9121315146567643,-0.07107893462425983,1.8644711387133321
3,210
Renal agenesis
15
54
2.204161
0.027513
Q15058,Q8WWQ0,Q15392,P61254,P18077,P62273,Q9UBM7,O43924,Q00534,P62857,P60953,Q96C36,P42766,Q86XL3,Q07020
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
421,198,68,6,257,40,191,71,619,253,270,406,554,223,482
1895,3027,2197,2459,71,1139,822,1588,1842,1148,257,2707,2574,1294,866,716,554,2150,867,2309,1363,991,270,6,1049,617,2766,1209,40,904,253,1302,2869,619,1553,482,421,68,1057,2444,2375,763,2419,1510,223,1115,198,406,768,1515,191,2923,2782,1964
-0.18562193543010477,-1.2685220944449345,-0.32863839725396865,-0.5000305276776785,2.243098964599965,0.1870894267741931,0.3883303529448472,-0.042424588305331204,-0.15699720383151142,0.1870894267741931,1.1388686667807886,-0.6996898275229555,-0.585637146978094,0.10096234789685095,0.35955846414598713,0.47469099999317105,0.6187714535547078,-0.30004918409410347,0.35955846414598713,-0.38579613781079947,0.07226934763416325,0.27328873734257736,1.1099198375930281,4.736544775086076,0.24454771184920537,0.5611177432905115,-0.7566787356245731,0.1583723191033171,2.8856731513793363,0.33079418522630977,1.1678236113059064,0.10096234789685095,-0.8990449194071448,0.5611177432905115,-0.013762661187869209,0.7053046416328677,0.7918996031387205,2.3305920279943764,0.24454771184920537,-0.4714819228517013,-0.4143647846958465,0.4458966875052482,-0.4429266939583211,0.014906920281284118,1.254724699862172,0.21581458325266947,1.3416792792210046,0.8207780604161526,0.4458966875052482,0.014906920281284118,1.399678167637441,-0.9843937111343767,-0.7566787356245731,-0.18562193543010477
3,210
U2 type spliceosomal complex
20
58
2.200296
0.027786
Q9NQ29,Q9Y333,Q6P2Q9,O60306,Q9Y383,O60508,P62316,Q15428,O60231,Q96DI7,P09234,P08621,Q9UBB9,O75533,P62314,O43172,Q9Y4Z0,O43660,P55769,Q9UNP9
Localization
GO Cellular component
msigdb_gocc
397,136,652,637,427,157,280,529,287,698,180,674,63,710,343,472,238,604,110,113
472,1191,1578,604,1580,287,637,157,1530,710,975,2141,1712,2706,674,180,1907,1537,1045,1425,110,1300,3049,343,280,1301,2104,1740,1308,2740,2659,2227,1213,1057,529,2958,2627,652,1682,2446,698,1877,1815,1453,397,1396,922,63,1343,1575,113,2753,136,427,1186,2342,238,777
0.7053046416328677,0.1583723191033171,-0.042424588305331204,0.5611177432905115,-0.042424588305331204,1.0520407045954674,0.532301591048701,1.5157445302511974,-0.013762661187869209,0.47469099999317105,0.27328873734257736,-0.30004918409410347,-0.0997257723165647,-0.6996898275229555,0.5034926557472869,1.428686242990915,-0.18562193543010477,-0.013762661187869209,0.24454771184920537,0.043584231076383116,1.806296713684594,0.10096234789685095,-1.3252822795048174,0.9363578339004853,1.0809771684172826,0.10096234789685095,-0.2714529942827711,-0.0997257723165647,0.10096234789685095,-0.7281873598507694,-0.6426760976202697,-0.32863839725396865,0.1583723191033171,0.24454771184920537,0.6476088916672819,-1.06969074968926,-0.614159800319998,0.532301591048701,-0.07107893462425983,-0.4714819228517013,0.5034926557472869,-0.15699720383151142,-0.1283651722112755,0.043584231076383116,0.8496631638098913,0.07226934763416325,0.33079418522630977,2.4473153810696386,0.10096234789685095,-0.013762661187869209,1.806296713684594,-0.7281873598507694,1.6319003291031084,0.7918996031387205,0.1870894267741931,-0.38579613781079947,1.2257516709181544,0.4458966875052482
3,210
er
22
94
2.19602
0.02809
Q9H6H4,Q9NQC3,O00264,Q8N4V1,P09132,Q86Y07,O60499,O96005,Q8NF37,O00767,Q86UL3,Q8NHH9,Q15392,Q9BRK0,O95470,O00400,Q14739,Q99640,Q9P2W9,Q9NPA0,Q06136,Q16850
Localization
OpenCell Localization
opencell_localization
276,285,149,30,33,292,288,42,301,173,315,317,68,338,323,321,222,90,107,382,115,127
149,321,173,3159,2754,603,1084,1835,635,288,1239,2024,3170,2892,1655,323,2988,42,1905,1713,930,1471,1472,33,1776,2094,640,1726,461,2833,1205,1046,2578,989,1156,869,833,1736,1920,753,1211,1551,836,115,483,2586,1932,2316,222,2991,3074,68,2444,2003,127,404,802,2374,2280,1509,315,292,30,1005,1067,301,317,657,3009,1869,2636,1265,625,1069,1173,90,338,961,964,3147,2486,276,1884,382,285,2018,1122,2071,107,2881,2856,2910,1763,1345
1.5447751873907711,0.9652690090027104,1.4577000206031279,-2.3435994424571596,-0.7566787356245731,0.5611177432905115,0.21581458325266947,-0.15699720383151142,0.532301591048701,1.0520407045954674,0.12966331135686696,-0.24284976542710374,-2.597271502186017,-0.9559499207681041,-0.07107893462425983,0.9652690090027104,-1.1549371513670597,2.827168320227334,-0.18562193543010477,-0.0997257723165647,0.3020375859379114,0.014906920281284118,0.014906920281284118,3.1784500806866625,-0.1283651722112755,-0.2714529942827711,0.532301591048701,-0.0997257723165647,0.7341628395132606,-0.8421163995463957,0.1583723191033171,0.24454771184920537,-0.585637146978094,0.27328873734257736,0.1870894267741931,0.35955846414598713,0.3883303529448472,-0.0997257723165647,-0.18562193543010477,0.4458966875052482,0.1583723191033171,-0.013762661187869209,0.3883303529448472,1.7772173493984713,0.7053046416328677,-0.585637146978094,-0.18562193543010477,-0.38579613781079947,1.254724699862172,-1.1549371513670597,-1.4103830170715437,2.3305920279943764,-0.4714819228517013,-0.21423943402394552,1.6900110425777688,0.8207780604161526,0.41710978314444397,-0.4143647846958465,-0.3572206950736908,0.014906920281284118,0.9941865778088491,1.0520407045954674,3.295675789963257,0.27328873734257736,0.24454771184920537,1.0231104921518903,0.9941865778088491,0.532301591048701,-1.2117404843314936,-0.15699720383151142,-0.614159800319998,0.12966331135686696,0.5611177432905115,0.24454771184920537,0.1870894267741931,2.0391177131346896,0.9652690090027104,0.3020375859379114,0.3020375859379114,-2.1742946413886646,-0.5000305276776785,1.1099198375930281,-0.15699720383151142,0.8785548612321639,1.0809771684172826,-0.21423943402394552,0.21581458325266947,-0.24284976542710374,1.8353813208718948,-0.8990449194071448,-0.8705836214377505,-0.9559499207681041,-0.0997257723165647,0.10096234789685095
3,210
Lethargy
34
84
2.187324
0.028719
P61254,P18077,Q9UMS0,O43772,Q8IUX1,P50416,O43676,P62273,P49748,Q9Y619,P42766,P23786,O75380,O14678,P49770,P12694,P45954,Q13144,Q9HC21,O00217,P40818,P42677,Q07020,P25490,Q86Y39,Q9BU61,Q96EY8,P61353,P12235,P40939,P49821,P20674,P62857,O75251
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
6,257,399,9,531,526,36,40,174,57,554,679,434,309,201,574,578,725,349,92,715,716,482,478,233,768,510,617,114,613,614,495,253,493
2565,92,309,36,9,493,822,434,1768,1350,2501,2570,785,1588,980,2538,3111,114,574,257,1040,495,1241,2028,679,478,1243,1783,2465,866,715,613,3121,716,554,578,867,2309,174,201,614,526,2914,1157,1297,991,6,1049,617,2766,1209,40,904,253,1302,2869,482,725,1500,1312,2771,233,531,3144,1804,1261,2851,510,3182,767,1875,768,1755,349,2178,3155,2251,1339,1820,399,2135,57,1893,1346
-0.585637146978094,1.9517715396466142,0.9941865778088491,3.0612894149232734,4.471263356608017,0.6764533068474775,0.3883303529448472,0.7630278449071122,-0.1283651722112755,0.07226934763416325,-0.5285725638095914,-0.585637146978094,0.41710978314444397,-0.042424588305331204,0.27328873734257736,-0.557108085715093,-1.778625708526751,1.7772173493984713,0.5899410509488118,1.1388686667807886,0.24454771184920537,0.6764533068474775,0.12966331135686696,-0.24284976542710374,0.5034926557472869,0.7053046416328677,0.12966331135686696,-0.1283651722112755,-0.5000305276776785,0.35955846414598713,0.47469099999317105,0.5611177432905115,-1.8634879482962017,0.47469099999317105,0.6187714535547078,0.5899410509488118,0.35955846414598713,-0.38579613781079947,1.4577000206031279,1.3126885452713448,0.5611177432905115,0.6476088916672819,-0.9843937111343767,0.1870894267741931,0.10096234789685095,0.27328873734257736,4.736544775086076,0.24454771184920537,0.5611177432905115,-0.7566787356245731,0.1583723191033171,2.8856731513793363,0.33079418522630977,1.1678236113059064,0.10096234789685095,-0.8990449194071448,0.7053046416328677,0.47469099999317105,0.014906920281284118,0.10096234789685095,-0.7566787356245731,1.2257516709181544,0.6476088916672819,-2.1178248450474757,-0.1283651722112755,0.12966331135686696,-0.8705836214377505,0.6764533068474775,-2.8506156435421364,0.4458966875052482,-0.15699720383151142,0.4458966875052482,-0.0997257723165647,0.9363578339004853,-0.30004918409410347,-2.258966469671713,-0.32863839725396865,0.10096234789685095,-0.1283651722112755,0.8496631638098913,-0.2714529942827711,2.534906450453798,-0.15699720383151142,0.10096234789685095
3,210
Ion transport by p type atpases
7
11
2.182346
0.029084
P05026,P23634,P54709,P16615,P20020,Q9HD20,P98194
Processes and pathways
Reactome Pathways
msigdb_reactome
476,70,167,386,458,155,723
713,476,386,458,70,1846,167,723,2108,1794,155
0.47469099999317105,0.7053046416328677,0.8496631638098913,0.7341628395132606,2.3014229202036454,-0.15699720383151142,1.4867194622568927,0.47469099999317105,-0.2714529942827711,-0.1283651722112755,1.5447751873907711
3,210
Aplasia hypoplasia of the skin
10
54
2.182008
0.029109
Q13126,Q8NCH0,Q9NWM8,Q15392,P53701,Q9H1A4,P22413,O75844,Q9Y619,O00170
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
89,163,35,68,354,275,47,294,57,124
124,1407,2495,1193,890,294,1140,1970,2802,1532,639,1976,1842,2090,1147,2865,1095,1535,2264,982,47,1043,1722,2353,2212,715,2356,1205,1849,354,1363,1925,1855,2585,558,89,686,1859,1251,2900,726,757,68,2055,163,3142,533,275,1951,408,35,1020,1761,57
1.6900110425777688,0.043584231076383116,-0.5285725638095914,0.1583723191033171,0.33079418522630977,1.0231104921518903,0.1870894267741931,-0.21423943402394552,-0.8136432086046264,-0.013762661187869209,0.532301591048701,-0.21423943402394552,-0.15699720383151142,-0.2714529942827711,0.1870894267741931,-0.8990449194071448,0.21581458325266947,-0.013762661187869209,-0.3572206950736908,0.27328873734257736,2.6809820839637393,0.24454771184920537,-0.0997257723165647,-0.4143647846958465,-0.32863839725396865,0.47469099999317105,-0.4143647846958465,0.1583723191033171,-0.15699720383151142,0.9074531014169275,0.07226934763416325,-0.18562193543010477,-0.15699720383151142,-0.585637146978094,0.6187714535547078,2.0391177131346896,0.5034926557472869,-0.15699720383151142,0.12966331135686696,-0.9559499207681041,0.47469099999317105,0.4458966875052482,2.3305920279943764,-0.24284976542710374,1.5157445302511974,-2.0895832987920526,0.6476088916672819,1.1099198375930281,-0.18562193543010477,0.8207780604161526,3.1198615395312252,0.27328873734257736,-0.0997257723165647,2.534906450453798
3,210
Abnormal blood glucose concentration
28
94
2.168756
0.030101
Q9Y2Q9,P22695,O43772,Q4J6C6,O75879,Q16134,Q8IUX1,P50416,Q08426,O43676,P49748,O75844,Q4G176,O75380,Q8WWQ0,P35610,O95470,P12694,P45954,O00217,P53985,P25490,Q9Y5B0,Q86Y39,Q5XKP0,Q9H845,P40939,O75251
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
265,129,9,10,255,391,531,526,29,36,174,294,441,434,198,437,323,574,578,92,480,478,103,233,377,381,613,493
2565,92,36,9,493,822,434,1768,294,255,2348,323,1285,1532,1350,2883,2501,2570,1414,980,2538,3111,895,574,1145,2304,1038,1040,129,679,1418,478,1783,2895,1358,437,2465,936,1295,2436,613,1203,1204,1484,578,3196,174,614,526,2216,1733,480,990,1157,1297,2513,835,29,1369,1054,391,2660,2771,441,10,377,1322,233,531,3144,1261,198,807,2851,2836,767,1634,768,1752,2487,381,2178,3155,1393,2530,1339,2782,881,1460,265,1760,103,1893,1346
-0.585637146978094,1.9517715396466142,3.0612894149232734,4.471263356608017,0.6764533068474775,0.3883303529448472,0.7630278449071122,-0.1283651722112755,1.0231104921518903,1.1388686667807886,-0.4143647846958465,0.9652690090027104,0.10096234789685095,-0.013762661187869209,0.07226934763416325,-0.9275003379149459,-0.5285725638095914,-0.585637146978094,0.043584231076383116,0.27328873734257736,-0.557108085715093,-1.778625708526751,0.33079418522630977,0.5899410509488118,0.1870894267741931,-0.38579613781079947,0.24454771184920537,0.24454771184920537,1.660952980636015,0.5034926557472869,0.043584231076383116,0.7053046416328677,-0.1283651722112755,-0.9559499207681041,0.07226934763416325,0.7630278449071122,-0.5000305276776785,0.3020375859379114,0.10096234789685095,-0.4714819228517013,0.5611177432905115,0.1583723191033171,0.1583723191033171,0.014906920281284118,0.5899410509488118,-3.4405571683800065,1.4577000206031279,0.5611177432905115,0.6476088916672819,-0.32863839725396865,-0.0997257723165647,0.7053046416328677,0.27328873734257736,0.1870894267741931,0.10096234789685095,-0.5285725638095914,0.3883303529448472,3.295675789963257,0.07226934763416325,0.24454771184920537,0.8496631638098913,-0.6426760976202697,-0.7566787356245731,0.7630278449071122,4.353447366494844,0.8785548612321639,0.10096234789685095,1.2257516709181544,0.6476088916672819,-2.1178248450474757,0.12966331135686696,1.3416792792210046,0.41710978314444397,-0.8705836214377505,-0.8421163995463957,0.4458966875052482,-0.042424588305331204,0.4458966875052482,-0.0997257723165647,-0.5000305276776785,0.8785548612321639,-0.30004918409410347,-2.258966469671713,0.07226934763416325,-0.5285725638095914,0.10096234789685095,-0.7566787356245731,0.35955846414598713,0.043584231076383116,1.1388686667807886,-0.0997257723165647,1.8644711387133321,-0.15699720383151142,0.10096234789685095
3,210
Porphyrin containing compound metabolic process
6
19
2.168637
0.03011
P22830,P30519,P09601,O00264,P33527,P30536
Processes and pathways
GO Biological process
msigdb_gobp
77,186,239,149,151,94
149,929,1973,1714,239,77,1355,186,94,151,460,2438,832,2719,2377,319,2823,2491,1961
1.5447751873907711,0.3020375859379114,-0.21423943402394552,-0.0997257723165647,1.1967846271462892,2.1556490854488635,0.07226934763416325,1.399678167637441,1.9517715396466142,1.5447751873907711,0.7341628395132606,-0.4714819228517013,0.3883303529448472,-0.6996898275229555,-0.4143647846958465,0.9941865778088491,-0.8136432086046264,-0.5000305276776785,-0.18562193543010477
3,210
Decreased activity of mitochondrial complex i
13
38
2.166572
0.030267
P51970,Q86Y39,O43676,Q99757,O95298,Q9UBX3,Q969Y2,Q9H845,Q9Y584,Q70HW3,O75380,O00217,O75251
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
499,233,36,360,256,73,177,381,25,58,434,92,493
92,36,493,822,434,1768,256,1350,1040,1783,1597,614,499,2411,1733,1297,2629,2719,58,233,531,3144,1261,177,2851,852,1947,360,768,2487,1120,381,3155,1339,73,2458,25,1346
1.9517715396466142,3.0612894149232734,0.6764533068474775,0.3883303529448472,0.7630278449071122,-0.1283651722112755,1.1388686667807886,0.07226934763416325,0.24454771184920537,-0.1283651722112755,-0.042424588305331204,0.5611177432905115,0.6764533068474775,-0.4429266939583211,-0.0997257723165647,0.10096234789685095,-0.614159800319998,-0.6996898275229555,2.5057048530603376,1.2257516709181544,0.6476088916672819,-2.1178248450474757,0.12966331135686696,1.4577000206031279,-0.8705836214377505,0.3883303529448472,-0.18562193543010477,0.9074531014169275,0.4458966875052482,-0.5000305276776785,0.21581458325266947,0.8785548612321639,-2.258966469671713,0.10096234789685095,2.243098964599965,-0.4714819228517013,3.5303175206480657,0.10096234789685095
3,210
Aerobic respiration
21
83
2.156723
0.031027
P21912,P22695,O95298,Q15070,O43676,P15954,O14949,P14406,Q9UDW1,P40925,P30405,O75380,P31040,O00217,P31930,Q9H3K2,O95299,P61586,P20674,O75251,P00403
Processes and pathways
GO Biological process
msigdb_gobp
496,129,256,22,36,414,43,44,46,296,181,434,211,92,218,361,475,229,495,493,366
92,668,43,36,1408,1710,493,822,434,1409,1768,3128,2201,1836,256,475,366,1350,1974,1840,2614,785,1197,980,1199,1352,1716,786,44,1476,1658,2304,414,1040,495,1149,496,129,1289,1986,1783,181,1539,211,218,3187,899,2805,1044,1483,296,1664,2213,1426,3048,3138,614,682,499,1733,869,791,555,1297,229,794,1369,22,2277,1059,1681,2377,1223,2818,701,3141,1120,361,2909,2491,46,1821,1346
1.9517715396466142,0.5034926557472869,2.768680735877916,3.0612894149232734,0.043584231076383116,-0.0997257723165647,0.6764533068474775,0.3883303529448472,0.7630278449071122,0.043584231076383116,-0.1283651722112755,-1.9483080573558453,-0.32863839725396865,-0.15699720383151142,1.1388686667807886,0.7053046416328677,0.8785548612321639,0.07226934763416325,-0.21423943402394552,-0.15699720383151142,-0.614159800319998,0.41710978314444397,0.1583723191033171,0.27328873734257736,0.1583723191033171,0.07226934763416325,-0.0997257723165647,0.41710978314444397,2.768680735877916,0.014906920281284118,-0.07107893462425983,-0.38579613781079947,0.7918996031387205,0.24454771184920537,0.6764533068474775,0.1870894267741931,0.6764533068474775,1.660952980636015,0.10096234789685095,-0.21423943402394552,-0.1283651722112755,1.428686242990915,-0.013762661187869209,1.2837036718300274,1.254724699862172,-2.906871317124417,0.33079418522630977,-0.8136432086046264,0.24454771184920537,0.014906920281284118,1.0231104921518903,-0.07107893462425983,-0.32863839725396865,0.043584231076383116,-1.3252822795048174,-2.0613372865600548,0.5611177432905115,0.5034926557472869,0.6764533068474775,-0.0997257723165647,0.35955846414598713,0.41710978314444397,0.6187714535547078,0.10096234789685095,1.2257516709181544,0.41710978314444397,0.07226934763416325,3.6477312434971276,-0.3572206950736908,0.24454771184920537,-0.07107893462425983,-0.4143647846958465,0.1583723191033171,-0.8136432086046264,0.5034926557472869,-2.0613372865600548,0.21581458325266947,0.9074531014169275,-0.9559499207681041,-0.5000305276776785,2.73944346623199,-0.1283651722112755,0.10096234789685095
3,210
Ion transmembrane transport
48
151
2.144009
0.032032
Q9UHG3,Q9Y4W6,Q04917,P08183,O43772,O15439,P16615,Q9H2D1,P14854,Q9HD20,Q8IUH4,P42858,P33527,Q8N4V1,P54709,Q14847,Q8TB61,Q9Y277,Q9UDW1,Q6P4A7,Q06787,Q4KMQ2,Q9BQT8,O60831,O75844,P30405,Q8WWC4,Q9Y619,Q70HW3,P56385,O00299,P27695,P23634,Q9UBX3,O00400,P20020,Q9HC21,Q14728,P31930,P53985,P05026,P07384,P20674,Q9H2J7,P12235,P08195,O75251,P00403
Processes and pathways
GO Biological process
msigdb_gobp
2,400,134,7,9,13,386,16,523,155,282,525,151,30,167,559,169,570,46,299,558,298,446,546,294,181,318,57,58,555,428,436,70,73,321,458,349,95,218,480,476,352,495,512,114,121,493,366
428,321,668,1896,13,1579,9,605,1651,889,546,929,744,493,2399,1088,294,2892,2201,1836,1140,673,366,713,476,931,784,894,1840,2612,352,1091,2147,7,121,1197,2863,1352,2884,114,2539,786,523,386,2865,2989,458,495,2264,2940,982,2306,70,1289,1986,436,1479,181,1846,2030,218,151,1596,1044,2097,1663,525,3019,2151,2270,1426,3048,2408,3109,2653,480,1101,167,942,791,555,2412,2361,2886,1737,2470,723,556,795,134,558,1672,1368,645,3189,1369,2715,1794,2318,2160,95,559,757,298,299,1168,58,2377,282,2114,3064,2919,30,1170,169,318,2011,2242,1633,2818,1327,2747,446,963,2963,3130,1120,16,512,2853,1755,2489,3165,349,155,2822,73,46,2075,2,1891,1820,1821,2881,570,1082,1233,400,57,1278,2938
0.7630278449071122,0.9652690090027104,0.5034926557472869,-0.18562193543010477,3.9415276975615496,-0.042424588305331204,4.471263356608017,0.5611177432905115,-0.07107893462425983,0.33079418522630977,0.6187714535547078,0.3020375859379114,0.4458966875052482,0.6764533068474775,-0.4429266939583211,0.21581458325266947,1.0231104921518903,-0.9559499207681041,-0.32863839725396865,-0.15699720383151142,0.1870894267741931,0.5034926557472869,0.8785548612321639,0.47469099999317105,0.7053046416328677,0.3020375859379114,0.41710978314444397,0.33079418522630977,-0.15699720383151142,-0.614159800319998,0.9074531014169275,0.21581458325266947,-0.30004918409410347,4.7070559039511,1.7190744805634337,0.1583723191033171,-0.8990449194071448,0.07226934763416325,-0.9275003379149459,1.7772173493984713,-0.557108085715093,0.41710978314444397,0.6476088916672819,0.8496631638098913,-0.8990449194071448,-1.1549371513670597,0.7341628395132606,0.6764533068474775,-0.3572206950736908,-1.0412640839639304,0.27328873734257736,-0.38579613781079947,2.3014229202036454,0.10096234789685095,-0.21423943402394552,0.7630278449071122,0.014906920281284118,1.428686242990915,-0.15699720383151142,-0.24284976542710374,1.254724699862172,1.5447751873907711,-0.042424588305331204,0.24454771184920537,-0.2714529942827711,-0.07107893462425983,0.6476088916672819,-1.2401339859422156,-0.30004918409410347,-0.3572206950736908,0.043584231076383116,-1.3252822795048174,-0.4429266939583211,-1.7220270950464363,-0.6426760976202697,0.7053046416328677,0.21581458325266947,1.4867194622568927,0.3020375859379114,0.41710978314444397,0.6187714535547078,-0.4429266939583211,-0.4143647846958465,-0.9275003379149459,-0.0997257723165647,-0.5000305276776785,0.47469099999317105,0.6187714535547078,0.41710978314444397,1.6319003291031084,0.6187714535547078,-0.07107893462425983,0.07226934763416325,0.532301591048701,-3.0474438546897957,0.07226934763416325,-0.6996898275229555,-0.1283651722112755,-0.38579613781079947,-0.30004918409410347,1.9517715396466142,0.6187714535547078,0.4458966875052482,1.0231104921518903,1.0231104921518903,0.1870894267741931,2.5057048530603376,-0.4143647846958465,1.0809771684172826,-0.2714529942827711,-1.3536544285197356,-0.9843937111343767,3.295675789963257,0.1870894267741931,1.4867194622568927,0.9941865778088491,-0.21423943402394552,-0.32863839725396865,-0.042424588305331204,-0.8136432086046264,0.10096234789685095,-0.7281873598507694,0.7630278449071122,0.3020375859379114,-1.06969074968926,-1.9483080573558453,0.21581458325266947,3.7945832692876573,0.6764533068474775,-0.8705836214377505,-0.0997257723165647,-0.5000305276776785,-2.456384063184641,0.9363578339004853,1.5447751873907711,-0.8136432086046264,2.243098964599965,2.73944346623199,-0.24284976542710374,5.326988510572498,-0.15699720383151142,-0.1283651722112755,-0.1283651722112755,-0.8990449194071448,0.6187714535547078,0.24454771184920537,0.1583723191033171,0.8496631638098913,2.534906450453798,0.12966331135686696,-1.0128317515561631
3,210
Ribosomal subunit
41
123
2.135577
0.032714
Q9Y2Q9,P51116,P61254,P18077,Q9H2W6,Q9BYC9,P46779,P30050,P61513,P47914,P62263,P62753,P62273,Q9BYD1,P42766,P50914,Q96A35,O60783,Q9Y3U8,P63220,P83881,P49207,P82912,Q96GC5,P62750,P62917,Q07020,P46776,P62910,Q6P1L8,P62888,P61353,P62857,P82914,P39023,Q9P015,P63244,P25398,P61247,P61927,P15880
Localization
GO Cellular component
msigdb_gocc
265,259,6,257,396,538,641,388,139,269,152,290,40,189,554,312,62,433,471,203,204,579,78,207,580,581,482,240,220,356,618,617,253,372,612,384,242,119,616,122,368
433,1906,3100,2760,2205,1588,979,1473,368,257,2462,746,2866,119,1419,828,388,1481,749,1725,866,612,2098,716,554,240,867,751,641,1485,642,2309,269,579,2546,312,259,1669,2411,991,616,6,1049,617,139,122,2766,1364,1209,2102,152,792,2897,40,1490,3020,1491,1210,580,290,1609,1927,904,2362,253,618,1302,2468,220,2869,581,793,203,242,1851,2513,1366,78,372,2846,2899,1611,204,905,1930,2583,482,870,2768,2223,2687,356,2630,3140,2326,1379,1263,62,3104,2118,207,960,1225,538,189,814,1449,2248,396,1516,1390,1391,2937,2639,1337,384,971,265,1025,1760,2187,2135,471
0.7630278449071122,-0.18562193543010477,-1.6370929036029538,-0.7566787356245731,-0.32863839725396865,-0.042424588305331204,0.27328873734257736,0.014906920281284118,0.8785548612321639,1.1388686667807886,-0.5000305276776785,0.4458966875052482,-0.8990449194071448,1.7481432606681047,0.043584231076383116,0.3883303529448472,0.8496631638098913,0.014906920281284118,0.4458966875052482,-0.0997257723165647,0.35955846414598713,0.5611177432905115,-0.2714529942827711,0.47469099999317105,0.6187714535547078,1.1967846271462892,0.35955846414598713,0.4458966875052482,0.532301591048701,0.014906920281284118,0.532301591048701,-0.38579613781079947,1.1099198375930281,0.5899410509488118,-0.557108085715093,0.9941865778088491,1.1388686667807886,-0.07107893462425983,-0.4429266939583211,0.27328873734257736,0.5611177432905115,4.736544775086076,0.24454771184920537,0.5611177432905115,1.602853122792676,1.7190744805634337,-0.7566787356245731,0.07226934763416325,0.1583723191033171,-0.2714529942827711,1.5447751873907711,0.41710978314444397,-0.9559499207681041,2.8856731513793363,0.014906920281284118,-1.2401339859422156,0.014906920281284118,0.1583723191033171,0.5899410509488118,1.0520407045954674,-0.042424588305331204,-0.18562193543010477,0.33079418522630977,-0.4143647846958465,1.1678236113059064,0.5611177432905115,0.10096234789685095,-0.5000305276776785,1.254724699862172,-0.8990449194071448,0.5899410509488118,0.41710978314444397,1.3126885452713448,1.1967846271462892,-0.15699720383151142,-0.5285725638095914,0.07226934763416325,2.1556490854488635,0.8785548612321639,-0.8705836214377505,-0.9559499207681041,-0.042424588305331204,1.3126885452713448,0.33079418522630977,-0.18562193543010477,-0.585637146978094,0.7053046416328677,0.35955846414598713,-0.7566787356245731,-0.32863839725396865,-0.6711860899363502,0.9074531014169275,-0.614159800319998,-2.0613372865600548,-0.38579613781079947,0.07226934763416325,0.12966331135686696,2.4473153810696386,-1.6654091771450312,-0.2714529942827711,1.3126885452713448,0.3020375859379114,0.1583723191033171,0.6476088916672819,1.399678167637441,0.41710978314444397,0.043584231076383116,-0.32863839725396865,0.8496631638098913,0.014906920281284118,0.07226934763416325,0.07226934763416325,-1.0128317515561631,-0.614159800319998,0.10096234789685095,0.8785548612321639,0.3020375859379114,1.1388686667807886,0.27328873734257736,-0.0997257723165647,-0.30004918409410347,-0.2714529942827711,0.7341628395132606
3,210
Atpase coupled transmembrane transporter activity
10
26
2.134975
0.032763
O14678,P23634,P08183,Q15388,O15439,P16615,P20020,Q9HD20,Q9NRK6,P33527
Functions
GO Molecular function
msigdb_gomf
309,70,7,355,13,386,458,155,319,151
309,13,929,713,476,1840,7,386,458,2264,2940,70,1292,151,3187,2097,1663,2412,723,1247,2887,355,155,319,1891,2824
0.9941865778088491,3.9415276975615496,0.3020375859379114,0.47469099999317105,0.7053046416328677,-0.15699720383151142,4.7070559039511,0.8496631638098913,0.7341628395132606,-0.3572206950736908,-1.0412640839639304,2.3014229202036454,0.10096234789685095,1.5447751873907711,-2.906871317124417,-0.2714529942827711,-0.07107893462425983,-0.4429266939583211,0.47469099999317105,0.12966331135686696,-0.9275003379149459,0.9074531014169275,1.5447751873907711,0.9941865778088491,-0.15699720383151142,-0.8136432086046264
3,210
Protein peptidyl prolyl isomerization
7
26
2.12305
0.03375
Q9Y680,Q9NWM8,Q9H2H8,Q9UNP9,P26885,P30405,O00170
Processes and pathways
GO Biological process
msigdb_gobp
194,35,133,113,53,181,124
124,888,1983,53,181,2788,2034,988,1737,2620,2655,724,2366,2714,403,2047,1555,2004,284,3129,133,35,113,2389,2342,194
1.6900110425777688,0.33079418522630977,-0.21423943402394552,2.593323246131426,1.428686242990915,-0.78516400280081,-0.24284976542710374,0.27328873734257736,-0.0997257723165647,-0.614159800319998,-0.6426760976202697,0.47469099999317105,-0.4143647846958465,-0.6996898275229555,0.8207780604161526,-0.24284976542710374,-0.013762661187869209,-0.21423943402394552,1.0809771684172826,-1.9483080573558453,1.660952980636015,3.1198615395312252,1.806296713684594,-0.4143647846958465,-0.38579613781079947,1.3706758332867983
3,210
Organophosphate ester transport
11
27
2.122074
0.033831
P08183,Q8TB61,O15439,Q9H2D1,Q4KMQ2,Q99808,Q8WTV0,O00400,P12235,P33527,P61916
Processes and pathways
GO Biological process
msigdb_gobp
7,169,13,16,298,208,19,321,114,151,278
321,13,605,3162,784,7,114,2539,1288,747,151,3187,1543,278,1853,3115,298,728,621,169,19,208,3141,3147,16,349,2071
0.9652690090027104,3.9415276975615496,0.5611177432905115,-2.42819419723944,0.41710978314444397,4.7070559039511,1.7772173493984713,-0.557108085715093,0.10096234789685095,0.4458966875052482,1.5447751873907711,-2.906871317124417,-0.013762661187869209,1.0809771684172826,-0.15699720383151142,-1.778625708526751,1.0231104921518903,0.47469099999317105,0.5611177432905115,1.4867194622568927,3.7358312584387403,1.3126885452713448,-2.0613372865600548,-2.1742946413886646,3.7945832692876573,0.9363578339004853,-0.24284976542710374
3,210
Abnormal cardiac ventricular function
7
22
2.108416
0.034995
Q15233,Q969Y2,P49748,P22413,O75844,P12235,P31040
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
205,177,174,47,294,114,211
294,2400,366,3162,1532,1350,980,1475,114,496,47,211,1784,2150,174,1616,906,205,2551,177,1875,2019
1.0231104921518903,-0.4429266939583211,0.8785548612321639,-2.42819419723944,-0.013762661187869209,0.07226934763416325,0.27328873734257736,0.014906920281284118,1.7772173493984713,0.6764533068474775,2.6809820839637393,1.2837036718300274,-0.1283651722112755,-0.30004918409410347,1.4577000206031279,-0.042424588305331204,0.33079418522630977,1.3126885452713448,-0.557108085715093,1.4577000206031279,-0.15699720383151142,-0.21423943402394552
3,210
Abnormal erythrocyte enzyme level
8
22
2.096585
0.03603
P61254,P18077,P62273,P62857,Q96RL7,P00813,P42766,Q07020
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
6,257,40,253,304,351,554,482
351,1588,257,866,716,554,867,2309,991,1102,6,1049,617,2766,1209,40,904,253,1302,2869,482,304
0.9074531014169275,-0.042424588305331204,1.1388686667807886,0.35955846414598713,0.47469099999317105,0.6187714535547078,0.35955846414598713,-0.38579613781079947,0.27328873734257736,0.21581458325266947,4.736544775086076,0.24454771184920537,0.5611177432905115,-0.7566787356245731,0.1583723191033171,2.8856731513793363,0.33079418522630977,1.1678236113059064,0.10096234789685095,-0.8990449194071448,0.7053046416328677,1.0231104921518903
3,210
metalloprotease
8
27
2.082494
0.037297
P22695,P31930,Q10713,P53582,Q5JRX3,O75844,P42892,Q7Z2K6
Functions
Panther Protein class
panther_protein_class
129,218,159,39,100,294,212,162
1582,2399,294,1469,2758,2090,1658,129,1422,218,212,2038,39,3043,159,100,2813,162,2171,2330,595,916,1517,2253,920,3026,400
-0.042424588305331204,-0.4429266939583211,1.0231104921518903,0.014906920281284118,-0.7566787356245731,-0.2714529942827711,-0.07107893462425983,1.660952980636015,0.043584231076383116,1.254724699862172,1.2837036718300274,-0.24284976542710374,2.8856731513793363,-1.2969048468084008,1.5157445302511974,1.8644711387133321,-0.8136432086046264,1.5157445302511974,-0.30004918409410347,-0.38579613781079947,0.5899410509488118,0.33079418522630977,0.014906920281284118,-0.32863839725396865,0.33079418522630977,-1.2401339859422156,0.8496631638098913
3,210
Cellular respiration
23
100
2.063989
0.039019
P21912,P22695,O95298,Q16134,Q15070,O43676,P15954,O14949,P14406,Q9UDW1,P40925,P30405,O75380,P31040,O00217,P31930,Q9H3K2,O95299,P61586,Q9NZ45,P20674,O75251,P00403
Processes and pathways
GO Biological process
msigdb_gobp
496,129,256,391,22,36,414,43,44,46,296,181,434,211,92,218,361,475,229,515,495,493,366
92,668,43,36,2459,1408,1710,493,822,434,1409,1768,1088,3128,2201,1836,256,475,366,1350,1972,2401,1974,1840,2614,785,1197,980,1199,1352,1716,786,1145,44,1476,1658,2304,414,1040,495,1149,496,129,1289,1986,1783,181,1539,211,218,3187,899,2805,1044,1483,1295,296,1664,2213,2684,1426,3048,3138,614,682,499,1733,869,791,555,1297,229,794,1615,1369,22,726,391,2277,1059,1681,2377,3032,2116,1744,1223,2818,701,1267,3141,1120,361,1755,515,2909,2491,46,1820,1821,1346
1.9517715396466142,0.5034926557472869,2.768680735877916,3.0612894149232734,-0.5000305276776785,0.043584231076383116,-0.0997257723165647,0.6764533068474775,0.3883303529448472,0.7630278449071122,0.043584231076383116,-0.1283651722112755,0.21581458325266947,-1.9483080573558453,-0.32863839725396865,-0.15699720383151142,1.1388686667807886,0.7053046416328677,0.8785548612321639,0.07226934763416325,-0.21423943402394552,-0.4429266939583211,-0.21423943402394552,-0.15699720383151142,-0.614159800319998,0.41710978314444397,0.1583723191033171,0.27328873734257736,0.1583723191033171,0.07226934763416325,-0.0997257723165647,0.41710978314444397,0.1870894267741931,2.768680735877916,0.014906920281284118,-0.07107893462425983,-0.38579613781079947,0.7918996031387205,0.24454771184920537,0.6764533068474775,0.1870894267741931,0.6764533068474775,1.660952980636015,0.10096234789685095,-0.21423943402394552,-0.1283651722112755,1.428686242990915,-0.013762661187869209,1.2837036718300274,1.254724699862172,-2.906871317124417,0.33079418522630977,-0.8136432086046264,0.24454771184920537,0.014906920281284118,0.10096234789685095,1.0231104921518903,-0.07107893462425983,-0.32863839725396865,-0.6711860899363502,0.043584231076383116,-1.3252822795048174,-2.0613372865600548,0.5611177432905115,0.5034926557472869,0.6764533068474775,-0.0997257723165647,0.35955846414598713,0.41710978314444397,0.6187714535547078,0.10096234789685095,1.2257516709181544,0.41710978314444397,-0.042424588305331204,0.07226934763416325,3.6477312434971276,0.47469099999317105,0.8496631638098913,-0.3572206950736908,0.24454771184920537,-0.07107893462425983,-0.4143647846958465,-1.2685220944449345,-0.2714529942827711,-0.0997257723165647,0.1583723191033171,-0.8136432086046264,0.5034926557472869,0.12966331135686696,-2.0613372865600548,0.21581458325266947,0.9074531014169275,-0.0997257723165647,0.6764533068474775,-0.9559499207681041,-0.5000305276776785,2.73944346623199,-0.1283651722112755,-0.1283651722112755,0.10096234789685095
3,210
Regulation of muscle adaptation
7
17
2.061665
0.03924
P25490,Q9Y5B0,P23634,P58546,Q14457,P16615,P49840
Processes and pathways
GO Biological process
msigdb_gobp
478,103,70,138,231,386,187
2757,712,1532,1035,2884,386,70,478,187,138,502,2517,2108,1794,1437,231,103
-0.7566787356245731,0.47469099999317105,-0.013762661187869209,0.24454771184920537,-0.9275003379149459,0.8496631638098913,2.3014229202036454,0.7053046416328677,1.399678167637441,1.602853122792676,0.6764533068474775,-0.5285725638095914,-0.2714529942827711,-0.1283651722112755,0.043584231076383116,1.2257516709181544,1.8644711387133321
3,210
External side of plasma membrane
6
22
2.06009
0.03939
P08183,O96005,O15439,P00390,Q13740,P42892
Localization
GO Cellular component
msigdb_gocc
7,42,13,324,54,212
13,891,1410,42,324,351,3162,2758,2204,894,609,7,2736,1658,575,2542,212,1916,3109,54,1437,1505
3.9415276975615496,0.33079418522630977,0.043584231076383116,2.827168320227334,0.9652690090027104,0.9074531014169275,-2.42819419723944,-0.7566787356245731,-0.32863839725396865,0.33079418522630977,0.5611177432905115,4.7070559039511,-0.7281873598507694,-0.07107893462425983,0.5899410509488118,-0.557108085715093,1.2837036718300274,-0.18562193543010477,-1.7220270950464363,2.593323246131426,0.043584231076383116,0.014906920281284118
3,210
Hormone metabolic process
6
27
2.05032
0.040333
Q8TC12,Q8NBN7,O75844,P42892,Q9UBM7,P30536
Processes and pathways
GO Biological process
msigdb_gobp
302,235,294,212,191,94
2086,891,294,323,713,1658,1416,1148,94,212,643,1296,1553,2370,2479,1801,235,1380,302,2794,2242,1634,2016,1953,191,1079,2255
-0.2714529942827711,0.33079418522630977,1.0231104921518903,0.9652690090027104,0.47469099999317105,-0.07107893462425983,0.043584231076383116,0.1870894267741931,1.9517715396466142,1.2837036718300274,0.532301591048701,0.10096234789685095,-0.013762661187869209,-0.4143647846958465,-0.5000305276776785,-0.1283651722112755,1.2257516709181544,0.07226934763416325,1.0231104921518903,-0.78516400280081,-0.32863839725396865,-0.042424588305331204,-0.21423943402394552,-0.18562193543010477,1.399678167637441,0.24454771184920537,-0.32863839725396865
3,210
Abnormal number of erythroid precursors
11
26
2.049737
0.04039
P61254,P18077,P62273,P61353,P62857,P04637,P42766,O75533,P62263,Q86SX6,Q07020
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
6,257,40,617,253,639,554,710,152,623,482
710,2611,639,1973,1588,257,866,716,554,867,2309,991,6,1049,617,2766,1209,152,40,904,253,1302,2869,482,623,1188
0.47469099999317105,-0.614159800319998,0.532301591048701,-0.21423943402394552,-0.042424588305331204,1.1388686667807886,0.35955846414598713,0.47469099999317105,0.6187714535547078,0.35955846414598713,-0.38579613781079947,0.27328873734257736,4.736544775086076,0.24454771184920537,0.5611177432905115,-0.7566787356245731,0.1583723191033171,1.5447751873907711,2.8856731513793363,0.33079418522630977,1.1678236113059064,0.10096234789685095,-0.8990449194071448,0.7053046416328677,0.5611177432905115,0.1870894267741931
3,210
Endothelial cell migration
7
36
2.049276
0.040435
P23634,P78536,P42785,P61586,Q8WTV0,O94813,P09601
Processes and pathways
GO Biological process
msigdb_gobp
70,168,76,229,19,118,239
1895,1239,118,2204,1286,894,1840,1975,1474,239,1659,2989,2913,70,1986,2542,1152,2998,76,989,2868,1298,229,438,2469,168,2367,1313,1505,585,802,19,336,2288,1753,1274
-0.18562193543010477,0.12966331135686696,1.7481432606681047,-0.32863839725396865,0.10096234789685095,0.33079418522630977,-0.15699720383151142,-0.21423943402394552,0.014906920281284118,1.1967846271462892,-0.07107893462425983,-1.1549371513670597,-0.9843937111343767,2.3014229202036454,-0.21423943402394552,-0.557108085715093,0.1870894267741931,-1.1833415521373098,2.184794201475348,0.27328873734257736,-0.8990449194071448,0.10096234789685095,1.2257516709181544,0.7630278449071122,-0.5000305276776785,1.4867194622568927,-0.4143647846958465,0.10096234789685095,0.014906920281284118,0.5899410509488118,0.41710978314444397,3.7358312584387403,0.9652690090027104,-0.3572206950736908,-0.0997257723165647,0.12966331135686696
3,210
Cytoplasmic ribosomal proteins
39
77
2.018508
0.043538
P35268,P46778,P61254,P18077,P84098,P46779,P30050,P61513,P47914,P46782,P62263,P62753,P62273,P62266,P63173,P42766,P50914,Q9Y3U8,P63220,P83881,P49207,P27635,P62750,P62917,Q07020,P42677,P46776,P62910,P62888,P61353,P62857,P39019,P46777,P39023,P25398,P61247,P61927,P15880,P18621
Processes and pathways
WikiPathways
msigdb_wp
749,751,6,257,905,641,388,139,269,642,152,290,40,792,793,554,312,471,203,204,579,828,580,581,482,716,240,220,618,617,253,866,867,612,119,616,122,368,746
3100,2760,2205,1588,979,368,257,2462,746,2866,119,1419,828,388,1481,749,1725,866,612,2098,716,554,240,867,751,641,1485,642,2309,269,579,2546,312,3177,991,616,6,1049,617,139,122,2766,1364,1209,2102,152,792,2897,40,1490,3020,1491,1210,580,290,1609,1927,904,2362,253,2581,618,1302,2468,220,2869,581,793,203,1611,204,905,1930,2583,482,3101,471
-1.6370929036029538,-0.7566787356245731,-0.32863839725396865,-0.042424588305331204,0.27328873734257736,0.8785548612321639,1.1388686667807886,-0.5000305276776785,0.4458966875052482,-0.8990449194071448,1.7481432606681047,0.043584231076383116,0.3883303529448472,0.8496631638098913,0.014906920281284118,0.4458966875052482,-0.0997257723165647,0.35955846414598713,0.5611177432905115,-0.2714529942827711,0.47469099999317105,0.6187714535547078,1.1967846271462892,0.35955846414598713,0.4458966875052482,0.532301591048701,0.014906920281284118,0.532301591048701,-0.38579613781079947,1.1099198375930281,0.5899410509488118,-0.557108085715093,0.9941865778088491,-2.738057757215477,0.27328873734257736,0.5611177432905115,4.736544775086076,0.24454771184920537,0.5611177432905115,1.602853122792676,1.7190744805634337,-0.7566787356245731,0.07226934763416325,0.1583723191033171,-0.2714529942827711,1.5447751873907711,0.41710978314444397,-0.9559499207681041,2.8856731513793363,0.014906920281284118,-1.2401339859422156,0.014906920281284118,0.1583723191033171,0.5899410509488118,1.0520407045954674,-0.042424588305331204,-0.18562193543010477,0.33079418522630977,-0.4143647846958465,1.1678236113059064,-0.585637146978094,0.5611177432905115,0.10096234789685095,-0.5000305276776785,1.254724699862172,-0.8990449194071448,0.5899410509488118,0.41710978314444397,1.3126885452713448,-0.042424588305331204,1.3126885452713448,0.33079418522630977,-0.18562193543010477,-0.585637146978094,0.7053046416328677,-1.6654091771450312,0.7341628395132606
3,210
Response to oxygen levels
21
64
2.01787
0.043605
Q96A26,P04637,Q8N511,Q13526,Q5SSJ5,P52789,P78536,O95352,P30519,Q9NQ88,Q92544,Q99808,P17655,O94966,P05026,Q99757,P00813,P61586,Q14457,P07237,P09601
Processes and pathways
GO Biological process
msigdb_gobp
4,639,18,403,689,527,168,179,186,598,206,208,575,322,476,360,351,229,231,609,239
1234,2343,1579,822,782,322,179,2828,1412,351,1532,2758,2401,639,476,2145,609,239,2461,575,1981,1535,2913,677,186,1539,2266,1663,1204,2355,2509,1916,2868,527,3043,2412,229,168,1855,403,231,2160,1056,3000,689,907,1004,18,1869,206,2904,4,2288,2242,1327,360,208,2125,598,2909,1079,1763,1830,1130
0.12966331135686696,-0.4143647846958465,-0.042424588305331204,0.3883303529448472,0.41710978314444397,0.9652690090027104,1.428686242990915,-0.8421163995463957,0.043584231076383116,0.9074531014169275,-0.013762661187869209,-0.7566787356245731,-0.4429266939583211,0.532301591048701,0.7053046416328677,-0.30004918409410347,0.5611177432905115,1.1967846271462892,-0.5000305276776785,0.5899410509488118,-0.21423943402394552,-0.013762661187869209,-0.9843937111343767,0.5034926557472869,1.399678167637441,-0.013762661187869209,-0.3572206950736908,-0.07107893462425983,0.1583723191033171,-0.4143647846958465,-0.5285725638095914,-0.18562193543010477,-0.8990449194071448,0.6476088916672819,-1.2969048468084008,-0.4429266939583211,1.2257516709181544,1.4867194622568927,-0.15699720383151142,0.8207780604161526,1.2257516709181544,-0.30004918409410347,0.24454771184920537,-1.1833415521373098,0.5034926557472869,0.33079418522630977,0.27328873734257736,3.7358312584387403,-0.15699720383151142,1.3126885452713448,-0.9559499207681041,5.1497245520076085,-0.3572206950736908,-0.32863839725396865,0.10096234789685095,0.9074531014169275,1.3126885452713448,-0.2714529942827711,0.5899410509488118,-0.9559499207681041,0.24454771184920537,-0.0997257723165647,-0.1283651722112755,0.21581458325266947
3,210
Protein targeting to membrane
10
35
2.014147
0.043994
P09132,Q9UHB9,O60725,P49458,Q9UL54,O43681,Q15629,P43307,A5D8V6,P56589
Processes and pathways
GO Biological process
msigdb_gobp
33,665,104,353,108,636,116,85,250,528
250,1235,2195,636,2731,104,1837,1472,33,2543,2895,900,2437,85,1789,353,1668,528,833,1736,2361,645,1673,116,2112,2236,1257,1567,1333,2335,1960,665,2075,108,1233
1.1678236113059064,0.12966331135686696,-0.32863839725396865,0.532301591048701,-0.7281873598507694,1.8353813208718948,-0.15699720383151142,0.014906920281284118,3.1784500806866625,-0.557108085715093,-0.9559499207681041,0.33079418522630977,-0.4714819228517013,2.0682431353184825,-0.1283651722112755,0.9074531014169275,-0.07107893462425983,0.6476088916672819,0.3883303529448472,-0.0997257723165647,-0.4143647846958465,0.532301591048701,-0.07107893462425983,1.7772173493984713,-0.2714529942827711,-0.32863839725396865,0.12966331135686696,-0.013762661187869209,0.10096234789685095,-0.38579613781079947,-0.18562193543010477,0.532301591048701,-0.24284976542710374,1.8353813208718948,0.1583723191033171
3,210
Ribosomal large subunit biogenesis
21
60
2.00048
0.045448
P61254,P18077,Q9BYC9,Q9Y221,Q9GZL7,Q9NUL7,Q9BZE4,Q8IY81,Q9UHA3,O00541,O75683,O95478,P42766,P50914,O60287,P62750,Q5SY16,P55769,O76021,P39023,Q9H7B2
Processes and pathways
GO Biological process
msigdb_gobp
6,257,538,544,407,286,426,695,568,545,671,550,554,312,310,580,344,110,607,612,254
545,925,310,671,607,550,2205,1976,257,2462,828,612,554,681,867,312,110,1546,6,1491,580,2468,2869,793,1611,2583,2476,2321,344,2687,1003,2688,695,1807,1692,1814,538,1449,1177,426,407,254,2699,1181,969,286,1123,1886,2454,1756,1020,1520,2909,568,1184,544,2188,2391,1026,2190
0.6187714535547078,0.3020375859379114,0.9941865778088491,0.5034926557472869,0.5611177432905115,0.6187714535547078,-0.32863839725396865,-0.21423943402394552,1.1388686667807886,-0.5000305276776785,0.3883303529448472,0.5611177432905115,0.6187714535547078,0.5034926557472869,0.35955846414598713,0.9941865778088491,1.806296713684594,-0.013762661187869209,4.736544775086076,0.014906920281284118,0.5899410509488118,-0.5000305276776785,-0.8990449194071448,0.41710978314444397,-0.042424588305331204,-0.585637146978094,-0.5000305276776785,-0.38579613781079947,0.9363578339004853,-0.6711860899363502,0.27328873734257736,-0.6711860899363502,0.5034926557472869,-0.1283651722112755,-0.07107893462425983,-0.1283651722112755,0.6476088916672819,0.043584231076383116,0.1870894267741931,0.7918996031387205,0.8207780604161526,1.1678236113059064,-0.6711860899363502,0.1870894267741931,0.3020375859379114,1.0809771684172826,0.21581458325266947,-0.15699720383151142,-0.4714819228517013,-0.0997257723165647,0.27328873734257736,0.014906920281284118,-0.9559499207681041,0.6187714535547078,0.1870894267741931,0.6476088916672819,-0.30004918409410347,-0.4143647846958465,0.27328873734257736,-0.30004918409410347
3,210
Mitochondrial electron transport nadh to ubiquinone
8
22
1.999065
0.045601
P51970,O43676,O95299,O95298,P49821,O75380,O00217,O75251
Processes and pathways
GO Biological process
msigdb_gobp
499,36,475,256,614,434,92,493
92,668,36,1710,493,822,434,1768,256,475,1350,980,1040,1783,614,499,1297,2277,1059,2818,1120,1346
1.9517715396466142,0.5034926557472869,3.0612894149232734,-0.0997257723165647,0.6764533068474775,0.3883303529448472,0.7630278449071122,-0.1283651722112755,1.1388686667807886,0.7053046416328677,0.07226934763416325,0.27328873734257736,0.24454771184920537,-0.1283651722112755,0.5611177432905115,0.6764533068474775,0.10096234789685095,-0.3572206950736908,0.24454771184920537,-0.8136432086046264,0.21581458325266947,0.10096234789685095
3,210
Lipid homeostasis
9
30
1.997663
0.045753
Q9BWH2,O15260,Q9HCL2,Q5BJF2,O15254,Q8WTV0,Q9NQC3,Q9Y6C9,P61916
Processes and pathways
GO Biological process
msigdb_gobp
339,99,236,8,144,19,285,26,278
1134,862,144,99,1141,3162,2207,1722,3187,437,278,796,998,8,2551,2552,1168,2283,19,2746,336,2288,339,1701,236,514,285,3099,2336,26
0.1870894267741931,0.35955846414598713,1.5738113969759262,1.8644711387133321,0.1870894267741931,-2.42819419723944,-0.32863839725396865,-0.0997257723165647,-2.906871317124417,0.7630278449071122,1.0809771684172826,0.41710978314444397,0.27328873734257736,4.55966070066017,-0.557108085715093,-0.557108085715093,0.1870894267741931,-0.3572206950736908,3.7358312584387403,-0.7281873598507694,0.9652690090027104,-0.3572206950736908,0.9652690090027104,-0.07107893462425983,1.2257516709181544,0.6764533068474775,1.0809771684172826,-1.6087717126857795,-0.38579613781079947,3.500973660498011
3,210
Abnormal hemoglobin
13
26
1.987492
0.046868
P42677,Q9UKG1,P61254,P18077,P62273,P62847,P61353,P62857,Q96MF7,P39019,P46777,P42766,Q07020
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
716,881,6,257,40,904,617,253,273,866,867,554,482
890,1713,1588,257,866,716,554,2150,867,2309,991,1736,6,1049,617,2766,1209,40,904,253,1302,2869,482,273,881,2186
0.33079418522630977,-0.0997257723165647,-0.042424588305331204,1.1388686667807886,0.35955846414598713,0.47469099999317105,0.6187714535547078,-0.30004918409410347,0.35955846414598713,-0.38579613781079947,0.27328873734257736,-0.0997257723165647,4.736544775086076,0.24454771184920537,0.5611177432905115,-0.7566787356245731,0.1583723191033171,2.8856731513793363,0.33079418522630977,1.1678236113059064,0.10096234789685095,-0.8990449194071448,0.7053046416328677,1.1099198375930281,0.35955846414598713,-0.30004918409410347
3,210
Receptor
8
41
1.983712
0.047288
Q99720,Q9NZT2,Q9NS69,P35613,Q8WTV0,P24390,O00264,Q9Y2I1
Functions
Protein Atlas Molecular function
protein_atlas_molecular_function
34,72,12,81,19,150,149,64
149,2345,862,603,891,3162,2758,2883,894,1974,1472,979,2864,2736,3149,1658,3085,369,150,2030,81,2898,1162,3115,1437,2160,222,1252,19,2011,336,1174,1327,34,12,72,924,64,859,1345,2799
1.5447751873907711,-0.4143647846958465,0.35955846414598713,0.5611177432905115,0.33079418522630977,-2.42819419723944,-0.7566787356245731,-0.9275003379149459,0.33079418522630977,-0.21423943402394552,0.014906920281284118,0.27328873734257736,-0.8990449194071448,-0.7281873598507694,-2.202522941644554,-0.07107893462425983,-1.4670908909749114,0.8785548612321639,1.5447751873907711,-0.24284976542710374,2.126508850206382,-0.9559499207681041,0.1870894267741931,-1.778625708526751,0.043584231076383116,-0.30004918409410347,1.254724699862172,0.12966331135686696,3.7358312584387403,-0.21423943402394552,0.9652690090027104,0.1870894267741931,0.10096234789685095,3.1784500806866625,4.0297378918795586,2.243098964599965,0.33079418522630977,2.4473153810696386,0.3883303529448472,0.10096234789685095,-0.78516400280081
3,210
Complex i biogenesis
10
28
1.978212
0.047905
P51970,Q86Y39,O43676,O95299,O95298,Q9P0J0,Q9H845,O75380,O00217,O75251
Processes and pathways
Reactome Pathways
msigdb_reactome
499,233,36,475,256,14,381,434,92,493
92,36,1710,493,822,434,1768,256,475,1350,1040,1783,614,499,1297,2277,1059,233,531,3144,1261,1693,768,381,3155,1339,14,1346
1.9517715396466142,3.0612894149232734,-0.0997257723165647,0.6764533068474775,0.3883303529448472,0.7630278449071122,-0.1283651722112755,1.1388686667807886,0.7053046416328677,0.07226934763416325,0.24454771184920537,-0.1283651722112755,0.5611177432905115,0.6764533068474775,0.10096234789685095,-0.3572206950736908,0.24454771184920537,1.2257516709181544,0.6476088916672819,-2.1178248450474757,0.12966331135686696,-0.07107893462425983,0.4458966875052482,0.8785548612321639,-2.258966469671713,0.10096234789685095,3.9121315146567643,0.10096234789685095
3,210
P-type ATPases
6
7
1.970446
0.048787
P05026,P23634,P54709,P16615,P98194,P20020
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
476,70,167,386,723,458
713,476,386,458,70,167,723
0.47469099999317105,0.7053046416328677,0.8496631638098913,0.7341628395132606,2.3014229202036454,1.4867194622568927,0.47469099999317105
3,210
Lipid transporter activity
6
21
1.968979
0.048956
P08183,O15439,Q4KMQ2,P33527,P61916,P30536
Functions
GO Molecular function
msigdb_gomf
7,13,298,151,278,94
309,862,13,7,1980,1288,1292,94,151,3187,1543,278,1853,298,2280,621,957,2120,1331,3147,467
0.9941865778088491,0.35955846414598713,3.9415276975615496,4.7070559039511,-0.21423943402394552,0.10096234789685095,0.10096234789685095,1.9517715396466142,1.5447751873907711,-2.906871317124417,-0.013762661187869209,1.0809771684172826,-0.15699720383151142,1.0231104921518903,-0.3572206950736908,0.5611177432905115,0.3020375859379114,-0.2714529942827711,0.10096234789685095,-2.1742946413886646,0.7341628395132606
3,210
Rac1 gtpase cycle
15
44
1.965452
0.049362
Q86Y07,Q14155,P63000,P63167,Q9H0H5,P60953,Q9UQB8,Q68EM7,O15498,Q13112,P50402,P42166,P42167,Q9Y2I1,Q14739
Processes and pathways
Reactome Pathways
msigdb_reactome
292,160,438,241,274,270,453,153,518,582,370,342,680,64,222
2825,518,1771,823,2758,894,342,680,2035,370,1601,2101,270,438,241,2586,582,2106,2046,160,1311,1250,222,2003,1679,153,2552,1862,2553,954,292,1866,1115,733,873,1946,961,274,2177,1228,453,1024,64,1761
-0.8421163995463957,0.6476088916672819,-0.1283651722112755,0.3883303529448472,-0.7566787356245731,0.33079418522630977,0.9363578339004853,0.5034926557472869,-0.24284976542710374,0.8785548612321639,-0.042424588305331204,-0.2714529942827711,1.1099198375930281,0.7630278449071122,1.1967846271462892,-0.585637146978094,0.5899410509488118,-0.2714529942827711,-0.24284976542710374,1.5157445302511974,0.10096234789685095,0.12966331135686696,1.254724699862172,-0.21423943402394552,-0.07107893462425983,1.5447751873907711,-0.557108085715093,-0.15699720383151142,-0.557108085715093,0.3020375859379114,1.0520407045954674,-0.15699720383151142,0.21581458325266947,0.47469099999317105,0.35955846414598713,-0.18562193543010477,0.3020375859379114,1.1099198375930281,-0.30004918409410347,0.1583723191033171,0.7630278449071122,0.27328873734257736,2.4473153810696386,-0.0997257723165647
3,210
reductase
9
29
1.964746
0.049444
Q15392,Q9H7Z7,Q9UDW1,Q8N8N7,P00390,Q06136,Q14914,Q14739,Q9UBM7
Functions
Panther Protein class
panther_protein_class
68,306,46,141,324,115,86,222,191
2257,2757,1531,2803,1713,324,1971,552,2304,1416,3143,1242,1355,2095,2353,984,115,222,86,68,2772,2918,623,141,406,306,2561,191,46
-0.3572206950736908,-0.7566787356245731,-0.013762661187869209,-0.8136432086046264,-0.0997257723165647,0.9652690090027104,-0.21423943402394552,0.6187714535547078,-0.38579613781079947,0.043584231076383116,-2.1178248450474757,0.12966331135686696,0.07226934763416325,-0.2714529942827711,-0.4143647846958465,0.27328873734257736,1.7772173493984713,1.254724699862172,2.0682431353184825,2.3305920279943764,-0.7566787356245731,-0.9843937111343767,0.5611177432905115,1.602853122792676,0.8207780604161526,1.0231104921518903,-0.557108085715093,1.399678167637441,2.73944346623199
3,210
HAD superfamily [IPR023214]
8
19
1.963506
0.049587
Q9Y5B0,P23634,P16615,P20020,Q9HD20,P98194,Q8NFW8,Q5TFE4
Sequence
InterPro Superfamily
interpro_homologous_superfamily
103,70,386,458,155,723,56,690
2192,713,386,458,70,1544,723,1215,690,56,911,1631,2922,2796,1699,1881,1227,155,103
-0.32863839725396865,0.47469099999317105,0.8496631638098913,0.7341628395132606,2.3014229202036454,-0.013762661187869209,0.47469099999317105,0.1583723191033171,0.5034926557472869,2.564112589516673,0.33079418522630977,-0.042424588305331204,-0.9843937111343767,-0.78516400280081,-0.07107893462425983,-0.15699720383151142,0.1583723191033171,1.5447751873907711,1.8644711387133321
3,210
HAD-like superfamily [IPR036412]
8
19
1.963506
0.049587
Q9Y5B0,P23634,P16615,P20020,Q9HD20,P98194,Q8NFW8,Q5TFE4
Sequence
InterPro Superfamily
interpro_homologous_superfamily
103,70,386,458,155,723,56,690
2192,713,386,458,70,1544,723,1215,690,56,911,1631,2922,2796,1699,1881,1227,155,103
-0.32863839725396865,0.47469099999317105,0.8496631638098913,0.7341628395132606,2.3014229202036454,-0.013762661187869209,0.47469099999317105,0.1583723191033171,0.5034926557472869,2.564112589516673,0.33079418522630977,-0.042424588305331204,-0.9843937111343767,-0.78516400280081,-0.07107893462425983,-0.15699720383151142,0.1583723191033171,1.5447751873907711,1.8644711387133321
3,210
Tissue migration
11
55
1.962409
0.049715
O75122,Q96E22,P78536,P23634,P42785,P61586,Q92766,Q8WTV0,O94813,Q9NQC3,P09601
Processes and pathways
GO Biological process
msigdb_gobp
65,336,168,70,76,229,445,19,118,285,239
1895,65,1239,118,2609,2204,1286,894,1840,1975,2650,1474,239,1659,2989,2913,70,1986,2542,1724,1152,2998,1204,76,989,2868,1298,1734,229,2845,438,2469,168,1553,2517,2367,1311,727,2003,1313,1505,585,802,803,19,445,336,2288,1753,3090,285,878,1274,1646,1647
-0.18562193543010477,2.4181275560384297,0.12966331135686696,1.7481432606681047,-0.614159800319998,-0.32863839725396865,0.10096234789685095,0.33079418522630977,-0.15699720383151142,-0.21423943402394552,-0.6426760976202697,0.014906920281284118,1.1967846271462892,-0.07107893462425983,-1.1549371513670597,-0.9843937111343767,2.3014229202036454,-0.21423943402394552,-0.557108085715093,-0.0997257723165647,0.1870894267741931,-1.1833415521373098,0.1583723191033171,2.184794201475348,0.27328873734257736,-0.8990449194071448,0.10096234789685095,-0.0997257723165647,1.2257516709181544,-0.8705836214377505,0.7630278449071122,-0.5000305276776785,1.4867194622568927,-0.013762661187869209,-0.5285725638095914,-0.4143647846958465,0.10096234789685095,0.47469099999317105,-0.21423943402394552,0.10096234789685095,0.014906920281284118,0.5899410509488118,0.41710978314444397,0.41710978314444397,3.7358312584387403,0.7630278449071122,0.9652690090027104,-0.3572206950736908,-0.0997257723165647,-1.4954371449930277,1.0809771684172826,0.35955846414598713,0.12966331135686696,-0.042424588305331204,-0.042424588305331204
3,210
Sphingolipid de novo biosynthesis
6
11
2.438547
0.014746
P51648,Q06136,O95470,Q96G23,P27544,O15121
Processes and pathways
Reactome Pathways
msigdb_reactome
37,199,101,73,208,26
26,278,1710,1772,101,1487,208,37,199,73,1648
3.0239793639306813,1.401134087308939,-0.1964126828419297,-0.22634804876060674,2.0870284690553733,-0.06395305747605311,1.630770150005915,2.822510997047098,1.661241829099701,2.2685902357175696,-0.15185455240937126
3,210
Sphingolipid metabolism integrated pathway
6
9
2.419475
0.015543
Q16739,Q06136,O95470,Q96G23,P27544,O15121
Processes and pathways
WikiPathways
msigdb_wp
33,199,101,73,208,26
26,278,1710,101,208,199,666,33,73
3.0239793639306813,1.401134087308939,-0.1964126828419297,2.0870284690553733,1.630770150005915,1.661241829099701,0.6498584271230965,2.90102584126154,2.2685902357175696
3,210
Sphingolipid metabolism overview
6
9
2.419475
0.015543
Q16739,Q06136,O95470,Q96G23,P27544,O15121
Processes and pathways
WikiPathways
msigdb_wp
33,199,101,73,208,26
26,278,1710,101,208,199,666,33,73
3.0239793639306813,1.401134087308939,-0.1964126828419297,2.0870284690553733,1.630770150005915,1.661241829099701,0.6498584271230965,2.90102584126154,2.2685902357175696
3,210
Sphingolipid metabolism
7
10
2.355147
0.018515
P04062,Q16739,P17900,Q06136,O95470,P07602,O15269
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
126,33,103,199,101,52,278
278,1710,101,126,52,103,199,666,33,326
1.401134087308939,-0.1964126828419297,2.0870284690553733,1.9746479174832445,2.5954221021396817,2.0870284690553733,1.661241829099701,0.6498584271230965,2.90102584126154,1.2710445729919746
3,210
Regulation of lysosomal lumen ph
6
7
2.241854
0.024971
Q9HC07,Q8N511,P50897,Q9NWW5,O75503,O75787
Processes and pathways
GO Biological process
msigdb_gobp
97,13,138,431,210,446
210,446,138,13,603,97,431
1.6205693247136275,0.9880603023396407,1.917441041803686,3.2893663916259843,0.7366749914819102,2.1055017317691553,1.0344802841599925
3,210
Cristae formation
8
9
2.225201
0.026068
Q9BUR5,O95202,Q6UXV4,Q5XKP0,Q9Y512,Q9NX63,Q9Y4W6,Q16891
Processes and pathways
GO Biological process
msigdb_gobp
131,356,296,175,307,507,416,318
356,318,175,296,131,591,507,416,307
1.204643279521078,1.2820220819729822,1.7515006919655713,1.347361260466732,1.955655640787987,0.7611934819569155,0.881937017334852,1.069001611287548,1.3256809556487925
3,210
Intermediate filament, rod domain [IPR039008]
7
8
2.160089
0.030766
Q16352,P20700,P07197,P48681,P08670,Q03252,P07196
Sequence
InterPro Domain
interpro_domain
195,513,294,549,109,436,118
647,118,294,109,513,549,436,195
0.6748240642101201,2.0124054126852844,1.347361260466732,2.049864066587316,0.858030796157992,0.8098570200405039,1.0229175049605006,1.6713557593392439
3,210
Intermediate filament protein, conserved site [IPR018039]
7
8
2.160089
0.030766
Q16352,P20700,P07197,P48681,P08670,Q03252,P07196
Sequence
InterPro Conserved site
interpro_conserved_site
195,513,294,549,109,436,118
647,118,294,109,513,549,436,195
0.6748240642101201,2.0124054126852844,1.347361260466732,2.049864066587316,0.858030796157992,0.8098570200405039,1.0229175049605006,1.6713557593392439
3,210
Intrinsic component of golgi membrane
7
10
2.112281
0.034662
Q9Y282,Q969X5,O95070,L0R6Q1,O15258,O43505,Q8TB61
Localization
GO Cellular component
msigdb_gocc
146,406,211,181,343,253,94
181,343,253,211,509,1025,957,94,406,146
1.7315909829794818,1.2268799582772898,1.4859266544772944,1.6205693247136275,0.8699988396202327,0.2588974772737941,0.326307106439725,2.1239031058014124,1.0918779578760416,1.907839023170101
3,210
Endoplasmic reticulum tubular network organization
7
12
2.094929
0.036177
Q9H6H4,Q9BRK0,Q6NUK4,O95197,Q9NQC3,Q8NHH9,P57088
Processes and pathways
GO Biological process
msigdb_gobp
227,420,113,20,29,158,413
20,413,459,872,113,158,420,1350,1056,227,1763,29
3.1585531831086073,1.069001611287548,0.9529469707603657,0.41912045171734913,2.0311718054537344,1.8595348542432146,1.0575222062488734,0.022375928201394484,0.23166690476374294,1.569234054047289,-0.21135718574042264,2.9552150269553397
3,210
Cytochrome complex assembly
7
12
2.06201
0.039207
Q9BSK2,P53701,Q6DKK2,Q15070,O75880,Q69YU5,Q9Y2R0
Processes and pathways
GO Biological process
msigdb_gobp
39,361,365,18,275,24,95
670,275,1429,361,18,24,365,404,762,39,1800,95
0.6373266801028631,1.411816152011253,-0.03500473434976105,1.193485935738,3.20256521186496,3.07677395656104,1.182302430096535,1.0918779578760416,0.5358760637885005,2.7907337531247736,-0.22634804876060674,2.1147113706663596
3,210
Nucleotide transmembrane transport
7
8
2.053193
0.040054
Q9H2D1,P12235,Q9BSK2,P05141,P12236,O15439,Q8TB61
Processes and pathways
GO Biological process
msigdb_gobp
4,162,39,686,558,530,94
530,714,686,162,558,94,39,4
0.8340045251873066,0.586869580596862,0.6247620912906596,1.84007448351757,0.7977374297619025,2.1239031058014124,2.7907337531247736,3.836509503264616
3,210
ATP-binding cassette transporter family
6
9
2.052114
0.040159
Q03518,O75027,P08183,Q03519,O15439,P33897
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
384,482,389,535,530,191
530,482,389,623,1410,191,384,535,1141
0.8340045251873066,0.9175738044692829,1.1373043723370269,0.6996603267996259,-0.020595446965442143,1.6814481915121122,1.1485937357921607,0.8340045251873066,0.16290875045406936
3,210
Abc type transporter activity
8
11
2.051427
0.040225
Q03518,O75027,P08183,Q9HD20,Q03519,O15439,O14678,P33897
Functions
GO Molecular function
msigdb_gomf
384,482,389,81,535,530,565,191
565,530,482,389,623,1410,191,384,535,81,1141
0.7855870788576451,0.8340045251873066,0.9175738044692829,1.1373043723370269,0.6996603267996259,-0.020595446965442143,1.6814481915121122,1.1485937357921607,0.8340045251873066,2.232831781149459,0.16290875045406936
3,210
Ceramide biosynthetic process
6
10
2.049711
0.040393
P04062,Q16739,Q96G23,P27544,O15269,O15121
Processes and pathways
GO Biological process
msigdb_gobp
126,33,73,208,278,26
26,278,1710,126,208,666,33,403,73,711
3.0239793639306813,1.401134087308939,-0.1964126828419297,1.9746479174832445,1.630770150005915,0.6498584271230965,2.90102584126154,1.0918779578760416,2.2685902357175696,0.5995337121866889
3,210
ABC transporter type 1, transmembrane domain superfamily [IPR036640]
7
10
2.046212
0.040736
Q03518,O75027,P08183,Q03519,O15439,O14678,P33897
Sequence
InterPro Superfamily
interpro_homologous_superfamily
384,482,389,535,530,565,191
565,530,482,389,623,1410,191,384,535,1141
0.7855870788576451,0.8340045251873066,0.9175738044692829,1.1373043723370269,0.6996603267996259,-0.020595446965442143,1.6814481915121122,1.1485937357921607,0.8340045251873066,0.16290875045406936
3,210
Abc transporters
7
10
2.046212
0.040736
Q03518,O75027,P08183,Q03519,O15439,O14678,P33897
Processes and pathways
KEGG Pathways
msigdb_kegg
384,482,389,535,530,565,191
565,530,482,389,623,1410,191,384,535,1141
0.7855870788576451,0.8340045251873066,0.9175738044692829,1.1373043723370269,0.6996603267996259,-0.020595446965442143,1.6814481915121122,1.1485937357921607,0.8340045251873066,0.16290875045406936
3,210
ABC transporter type 1, transmembrane domain [IPR011527]
7
10
2.046212
0.040736
Q03518,O75027,P08183,Q03519,O15439,O14678,P33897
Sequence
InterPro Domain
interpro_domain
384,482,389,535,530,565,191
565,530,482,389,623,1410,191,384,535,1141
0.7855870788576451,0.8340045251873066,0.9175738044692829,1.1373043723370269,0.6996603267996259,-0.020595446965442143,1.6814481915121122,1.1485937357921607,0.8340045251873066,0.16290875045406936
3,210
Mitochondrial nucleotide transporter subfamily
8
9
2.036337
0.041717
Q9H2D1,P12235,Q9HC21,Q70HW3,Q9BSK2,Q6NUK1,P05141,P12236
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
4,162,260,66,39,657,686,558
714,686,162,558,657,66,39,4,260
0.586869580596862,0.6247620912906596,1.84007448351757,0.7977374297619025,0.6623574997738125,2.356818953824768,2.7907337531247736,3.836509503264616,1.47540985761985
3,210
Sphingolipid biosynthetic process
9
15
2.029405
0.042417
P04062,Q16739,Q06136,O95470,Q96G23,Q9P035,P27544,O15269,O15121
Processes and pathways
GO Biological process
msigdb_gobp
126,33,199,101,73,205,208,278,26
26,278,1710,101,126,1487,208,199,666,33,403,73,711,205,1648
3.0239793639306813,1.401134087308939,-0.1964126828419297,2.0870284690553733,1.9746479174832445,-0.06395305747605311,1.630770150005915,1.661241829099701,0.6498584271230965,2.90102584126154,1.0918779578760416,2.2685902357175696,0.5995337121866889,1.6409491149908735,-0.15185455240937126
3,210
Tetrapyrrole binding
9
16
2.029083
0.04245
Q9H7Z7,O43169,P09601,P53701,Q16850,O00264,Q6UW02,P30519,O15173
Functions
GO Molecular function
msigdb_gomf
325,38,40,361,107,51,57,28,62
51,62,38,1022,40,1923,28,361,107,57,404,1587,752,864,325,1259
2.5954221021396817,2.3916536040933773,2.7907337531247736,0.2588974772737941,2.7747641575162865,-0.3020077268703407,2.9859015171477754,1.193485935738,2.0684827664895757,2.5200380278463603,1.0918779578760416,-0.12237587478854399,0.5486753421710154,0.4322343646319835,1.2710445729919746,0.07908178905132351
3,210
calmodulin-related
6
10
2.020505
0.043331
Q9BPX6,P80303,Q02818,Q9BRK5,O43852,Q14257
Functions
Panther Protein class
panther_protein_class
448,6,47,177,116,151
116,1684,796,6,47,151,982,515,448,177
2.021797911431073,-0.18151426057096084,0.49727213928344227,3.798111606892421,2.6777899964295577,1.8789156496265464,0.29945651967751274,0.858030796157992,0.9880603023396407,1.7515006919655713
3,210
Class i peroxisomal membrane protein import
9
10
2.01958
0.043427
P33897,Q8NBU5,P51648,O75381,Q5T8D3,Q9NR77,P28288,P40855,P56589
Processes and pathways
Reactome Pathways
msigdb_reactome
191,654,37,136,139,77,623,122,383
714,136,623,191,122,37,383,139,654,77
0.586869580596862,1.927023636429267,0.6996603267996259,1.6814481915121122,2.0029942368825533,2.822510997047098,1.1485937357921607,1.917441041803686,0.6748240642101201,2.241796812015894
3,210
Endoplasmic reticulum tubular network
7
13
1.983538
0.047307
Q9H6H4,Q9BRK0,Q6NUK4,Q00765,P50402,Q9NQC3,Q8NHH9
Localization
GO Cellular component
msigdb_gocc
227,420,113,375,148,29,158
148,459,375,1321,2189,872,113,158,420,1350,227,1763,29
1.8885764048992375,0.9529469707603657,1.1598564515736667,0.036615047711478665,-0.4412506789391867,0.41912045171734913,2.0311718054537344,1.8595348542432146,1.0575222062488734,0.022375928201394484,1.569234054047289,-0.21135718574042264,2.9552150269553397
3,210
Protein transmembrane transporter activity
8
11
1.967118
0.04917
Q9NS69,Q9UGP8,Q99595,Q9Y584,P49755,Q07820,Q15388,O14925
Functions
GO Molecular function
msigdb_gomf
5,261,2,10,394,551,153,213
213,684,585,394,2077,551,153,2,5,261,10
1.6103465471343246,0.6247620912906596,0.7611934819569155,1.1146452073437958,-0.3788698240801004,0.8098570200405039,1.8789156496265464,3.836509503264616,3.836509503264616,1.47540985761985,3.506414357386638
3,210
Sphingolipid metabolism
6
13
1.960049
0.04999
P04062,Q16739,Q06136,O95470,O15269,O15121
Processes and pathways
KEGG Pathways
msigdb_kegg
126,33,199,101,278,26
26,278,1710,344,101,126,1571,1573,1740,199,666,33,711
3.0239793639306813,1.401134087308939,-0.1964126828419297,1.2268799582772898,2.0870284690553733,1.9746479174832445,-0.12237587478854399,-0.12237587478854399,-0.21135718574042264,1.661241829099701,0.6498584271230965,2.90102584126154,0.5995337121866889
3,210
Dysostosis multiplex
6
7
2.462649
0.013791
P54802,O00754,P04066,P10619,P15586,P16278
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
130,164,139,55,275,90
164,139,55,275,90,130,377
1.6551989417094066,1.7728328396449533,2.834506313368406,1.1254012693689186,2.2702148607681574,1.8555928595462654,0.9195049394408159
3,210
Sphingolipid metabolism integrated pathway
6
9
2.454054
0.014126
Q96G23,O15121,Q06136,Q13510,Q16739,O95470
Processes and pathways
WikiPathways
msigdb_wp
97,102,106,49,19,115
102,773,2542,115,165,106,49,19,97
2.145323291693078,0.44482842599710637,-0.6132162563523244,1.9859063385694156,1.6551989417094066,2.097891708372181,2.9477642917536246,3.770570742927153,2.176761289713973
3,210
Sphingolipid metabolism overview
6
9
2.454054
0.014126
Q96G23,O15121,Q06136,Q13510,Q16739,O95470
Processes and pathways
WikiPathways
msigdb_wp
97,102,106,49,19,115
102,773,2542,115,165,106,49,19,97
2.145323291693078,0.44482842599710637,-0.6132162563523244,1.9859063385694156,1.6551989417094066,2.097891708372181,2.9477642917536246,3.770570742927153,2.176761289713973
3,210
Sphingolipid metabolism
6
10
2.420215
0.015511
Q06136,P04062,P17900,Q13510,Q16739,P07602
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
106,44,76,49,19,83
773,2542,115,44,83,76,106,49,19,701
0.44482842599710637,-0.6132162563523244,1.9859063385694156,3.1143760455387404,2.347130772218854,2.4834554092716568,2.097891708372181,2.9477642917536246,3.770570742927153,0.526570177938448
3,210
Membrane lipid catabolic process
8
11
2.409877
0.015958
P06865,P50897,P06280,P04062,P04066,P17900,Q13510,O95470
Processes and pathways
GO Biological process
msigdb_gobp
225,35,201,44,139,76,49,115
115,44,139,201,225,2035,76,35,49,295,1246
1.9859063385694156,3.1143760455387404,1.7728328396449533,1.4484838393625152,1.3425958796740627,-0.3237426380487701,2.4834554092716568,3.27725211222102,2.9477642917536246,1.0884659720501764,0.1060924308462119
3,210
Sphingolipid metabolism in senescence
6
12
2.201997
0.027666
Q96G23,O15121,P04062,Q13510,Q16739,P16278
Processes and pathways
WikiPathways
msigdb_wp
97,102,44,49,19,90
102,773,44,310,90,1082,811,709,106,49,19,97
2.145323291693078,0.44482842599710637,3.1143760455387404,1.0513121178447833,2.2702148607681574,0.19262663846354372,0.4035341298811554,0.5062390987652113,2.097891708372181,2.9477642917536246,3.770570742927153,2.176761289713973
3,210
Sphingolipid metabolism
7
13
2.054456
0.039932
O15121,Q06136,P04062,Q13510,Q16739,O95470,P16278
Processes and pathways
KEGG Pathways
msigdb_kegg
102,106,44,49,19,115,90
102,773,2542,417,115,44,201,2700,90,106,49,19,1246
2.145323291693078,0.44482842599710637,-0.6132162563523244,0.8429102209698677,1.9859063385694156,3.1143760455387404,1.4484838393625152,-0.7384963885381698,2.2702148607681574,2.097891708372181,2.9477642917536246,3.770570742927153,0.1060924308462119
3,210
Sphingolipid biosynthetic process
7
15
2.051214
0.040246
Q96G23,O15121,Q06136,P04062,Q13510,Q16739,O95470
Processes and pathways
GO Biological process
msigdb_gobp
97,102,106,44,49,19,115
102,773,2542,115,44,2040,165,106,49,19,1608,97,1246,505,2491
2.145323291693078,0.44482842599710637,-0.6132162563523244,1.9859063385694156,3.1143760455387404,-0.3237426380487701,1.6551989417094066,2.097891708372181,2.9477642917536246,3.770570742927153,-0.09347842149372354,2.176761289713973,0.1060924308462119,0.7262001044800472,-0.5639012970998747
3,210
Glycosphingolipid metabolism
8
17
1.963234
0.049619
P06280,P04062,P17900,Q13510,P07602,Q16739,P10619,P16278
Processes and pathways
Reactome Pathways
msigdb_reactome
201,44,76,49,83,19,55,90
1536,417,44,201,225,83,2035,55,2700,90,76,49,19,2770,1619,1246,1580
-0.07095809716865134,0.8429102209698677,3.1143760455387404,1.4484838393625152,1.3425958796740627,2.347130772218854,-0.3237426380487701,2.834506313368406,-0.7384963885381698,2.2702148607681574,2.4834554092716568,2.9477642917536246,3.770570742927153,-0.7894335101320087,-0.09347842149372354,0.1060924308462119,-0.07095809716865134
3,210
Ion transmembrane transporter activity
33
100
3.653146
0.000259
Q9H2D1,P33527,P53985,P21796,P16615,Q14847,O00299,Q99808,Q9HD20,Q8TB61,Q8N4V1,O00400,Q9UBX3,Q6P4A7,P45880,Q70HW3,Q9Y619,O43772,O75964,Q93050,Q9UDW1,P00403,P12235,P31930,P23634,P14854,O43681,O75947,Q8N1S5,Q9Y277,Q8IUH4,P20674,P13073
Functions
GO Molecular function
msigdb_gomf
1,267,145,19,397,279,275,156,28,163,168,43,50,440,52,55,59,66,67,459,75,334,467,220,219,229,104,479,112,506,374,498,370
275,43,565,1867,104,66,2134,2050,479,67,2016,334,734,2416,2180,2993,2212,2274,2080,823,3142,1873,467,2686,370,229,397,1875,498,2339,3160,19,219,1318,3037,2083,220,267,2343,2571,2084,52,2383,3113,3048,2445,145,1658,1841,1500,1622,2960,2732,887,775,1504,2395,801,279,1048,3184,2671,1200,440,55,1237,374,112,168,1330,163,2357,2360,459,526,811,156,1937,3031,1251,2902,1,1772,1941,1969,560,746,28,2919,50,75,1563,2877,2169,506,731,1527,59,1688,2760
1.1487666995177788,2.687053265961324,0.6884687739263295,-0.1787578934323262,1.9387760747315386,2.311381403119757,-0.3543756565400391,-0.28808392260207233,0.7862799512775219,2.311381403119757,-0.2661038286652666,1.016858162020565,0.5297381122387874,-0.5338093246549072,-0.37659150480827835,-1.2202811138168626,-0.3988673947128502,-0.44360111347426245,-0.31012230394858126,0.44930601055840114,-2.030379226705189,-0.1787578934323262,0.8057169414204521,-0.7638342514312623,0.9597505084681618,1.2603787307732723,0.9214825561524033,-0.1787578934323262,0.7668015426370355,-0.48858049757519073,-2.2268000244687314,3.565072073980479,1.278853689347875,0.12003241207649194,-1.3702552416869775,-0.31012230394858126,1.278853689347875,1.1674604442373642,-0.48858049757519073,-0.6710317035777431,-0.31012230394858126,2.509065367944047,-0.5111634909229179,-1.785701460422968,-1.42092054737106,-0.556518486029154,1.6588461750842975,-0.0708373510934119,-0.15706295482882135,0.014520145426408674,-0.04941754059447337,-1.146393653735946,-0.8106447024352365,0.40881543685910227,0.4896128041999829,0.014520145426408674,-0.5111634909229179,0.4694822353754309,1.1487666995177788,0.30676947108334135,-2.7908471566158775,-0.740532149740219,0.20352212550695528,0.8444676370207627,2.4599952437757544,0.18272500423106916,0.9597505084681618,1.8695290813707817,1.5338312891339945,0.12003241207649194,1.5517889434452048,-0.48858049757519073,-0.48858049757519073,0.8251127563510817,0.7472814698483077,0.4694822353754309,1.6054641390302427,-0.20050904201939973,-1.3199310652066065,0.18272500423106916,-1.0248100286459398,5.424065052068769,-0.1138401084971145,-0.20050904201939973,-0.22231680626932795,0.7081153372030551,0.5297381122387874,3.15792453539255,-1.0489737282202127,2.557906632557138,2.2613651972231907,-0.006739164246572185,-0.9767075535898113,-0.3543756565400391,0.7668015426370355,0.5497334133991656,0.014520145426408674,2.4435871616487934,-0.0708373510934119,-0.8341541839153083
3,210
transporter
11
57
3.569631
0.000357
Q99595,Q9H2D1,O43772,Q9NR77,O43681,Q9Y584,Q15070,P53985,Q9HD45,Q9Y619,Q99808
Functions
Panther Protein class
panther_protein_class
0,1,66,136,104,13,45,145,26,59,156
1781,1185,1566,3112,2248,2132,937,104,66,1063,1486,2271,2306,2381,2661,1263,1584,3063,2423,1983,2445,145,2385,2028,2960,2449,1588,1589,45,3184,2950,1267,677,3080,1475,2288,1903,212,956,1964,2291,893,0,156,2491,1445,1,3070,624,26,136,2005,1216,2624,13,1914,59
-0.13542382527329797,0.20352212550695528,-0.028051602989249587,-1.785701460422968,-0.42120377836259065,-0.3543756565400391,0.36813874070508046,1.9387760747315386,2.311381403119757,0.286217363258279,0.014520145426408674,-0.44360111347426245,-0.46605986346971,-0.5111634909229179,-0.740532149740219,0.16187790183882575,-0.028051602989249587,-1.471933472086969,-0.5338093246549072,-0.24418159668346107,-0.556518486029154,1.6588461750842975,-0.5111634909229179,-0.2661038286652666,-1.146393653735946,-0.556518486029154,-0.028051602989249587,-0.028051602989249587,2.6065219729812474,-2.7908471566158775,-1.121922556458858,0.16187790183882575,0.5895906935815504,-1.5491193478204588,0.03572669165067375,-0.44360111347426245,-0.1787578934323262,1.3156964634073816,0.36813874070508046,-0.22231680626932795,-0.44360111347426245,0.40881543685910227,6.587934544608236,1.6054641390302427,-0.5792914685282397,0.05688083594047554,5.424065052068769,-1.4975723754350228,0.64904737623524,3.2649229530203527,1.7119394487268482,-0.24418159668346107,0.20352212550695528,-0.6941314197209414,3.915034698124895,-0.1787578934323262,2.4435871616487934
3,210
SLC superfamily of solute carriers
12
43
3.492122
0.000479
Q9H2D1,O43772,Q9BSK2,O00400,Q8N1S5,P53985,Q9UBX3,Q7L0J3,Q70HW3,Q9Y619,Q99808,Q9Y6C9
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
1,66,9,43,112,145,50,84,55,59,156,29
43,66,2134,2050,2016,2180,2080,467,2686,2083,2445,145,1658,887,775,3184,2671,1200,55,84,3147,112,163,2202,2357,526,156,1937,9,2902,1,1772,3070,1941,1969,560,746,686,50,2877,59,29,2760
2.687053265961324,2.311381403119757,-0.3543756565400391,-0.28808392260207233,-0.2661038286652666,-0.37659150480827835,-0.31012230394858126,0.8057169414204521,-0.7638342514312623,-0.31012230394858126,-0.556518486029154,1.6588461750842975,-0.0708373510934119,0.40881543685910227,0.4896128041999829,-2.7908471566158775,-0.740532149740219,0.20352212550695528,2.4599952437757544,2.160595878265183,-2.085931168920067,1.8695290813707817,1.5517889434452048,-0.37659150480827835,-0.48858049757519073,0.7472814698483077,1.6054641390302427,-0.20050904201939973,4.268651553761713,-1.0248100286459398,5.424065052068769,-0.1138401084971145,-1.4975723754350228,-0.20050904201939973,-0.22231680626932795,0.7081153372030551,0.5297381122387874,0.5895906935815504,2.557906632557138,-0.9767075535898113,2.4435871616487934,3.065374122452209,-0.8341541839153083
3,210
Mitochondrial carrier domain superfamily [IPR023395]
6
22
3.462163
0.000536
Q9H2D1,Q9BSK2,Q9UBX3,Q70HW3,Q9Y619,Q9Y6C9
Sequence
InterPro Superfamily
interpro_homologous_superfamily
1,9,50,55,59,29
66,2134,2050,2180,467,2686,2445,887,775,2671,55,2202,1937,9,1,1941,746,686,50,2877,59,29
2.311381403119757,-0.3543756565400391,-0.28808392260207233,-0.37659150480827835,0.8057169414204521,-0.7638342514312623,-0.556518486029154,0.40881543685910227,0.4896128041999829,-0.740532149740219,2.4599952437757544,-0.37659150480827835,-0.20050904201939973,4.268651553761713,5.424065052068769,-0.20050904201939973,0.5297381122387874,0.5895906935815504,2.557906632557138,-0.9767075535898113,2.4435871616487934,3.065374122452209
3,210
SLC25 family of mitochondrial transporters
6
22
3.462163
0.000536
Q9H2D1,Q9BSK2,Q9UBX3,Q70HW3,Q9Y619,Q9Y6C9
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
1,9,50,55,59,29
66,2134,2050,2180,467,2686,2445,887,775,2671,55,2202,1937,9,1,1941,746,686,50,2877,59,29
2.311381403119757,-0.3543756565400391,-0.28808392260207233,-0.37659150480827835,0.8057169414204521,-0.7638342514312623,-0.556518486029154,0.40881543685910227,0.4896128041999829,-0.740532149740219,2.4599952437757544,-0.37659150480827835,-0.20050904201939973,4.268651553761713,5.424065052068769,-0.20050904201939973,0.5297381122387874,0.5895906935815504,2.557906632557138,-0.9767075535898113,2.4435871616487934,3.065374122452209
3,210
Mitochondrial substrate/solute carrier [IPR018108]
6
22
3.462163
0.000536
Q9H2D1,Q9BSK2,Q9UBX3,Q70HW3,Q9Y619,Q9Y6C9
Sequence
InterPro Repeat
interpro_repeat
1,9,50,55,59,29
66,2134,2050,2180,467,2686,2445,887,775,2671,55,2202,1937,9,1,1941,746,686,50,2877,59,29
2.311381403119757,-0.3543756565400391,-0.28808392260207233,-0.37659150480827835,0.8057169414204521,-0.7638342514312623,-0.556518486029154,0.40881543685910227,0.4896128041999829,-0.740532149740219,2.4599952437757544,-0.37659150480827835,-0.20050904201939973,4.268651553761713,5.424065052068769,-0.20050904201939973,0.5297381122387874,0.5895906935815504,2.557906632557138,-0.9767075535898113,2.4435871616487934,3.065374122452209
3,210