term stringlengths 2 121 | overlap int64 6 281 | setsize int64 7 499 | score float64 1.96 10.6 | pval float64 0 0.05 | edge stringlengths 41 1.97k | type stringclasses 5
values | subtype stringclasses 24
values | subtype_key stringclasses 24
values | edge_idxs stringlengths 11 1.17k | ann_idxs stringlengths 19 2.31k | ann_vals stringlengths 124 9.94k | sig_size int64 2.2k 3.73k |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Large ribosomal subunit | 27 | 75 | 2.328196 | 0.019902 | P51116,Q9H2W6,P61254,P18077,Q9BYC9,P30050,P61513,P47914,Q9BYD1,P42766,P50914,Q96A35,Q9Y3U8,P83881,P49207,Q96GC5,P62750,P62917,Q07020,P62910,Q6P1L8,P62888,P61353,Q9P015,P39023,P46776,P61927 | Localization | GO Cellular component | msigdb_gocc | 259,396,6,257,538,388,139,269,189,554,312,62,471,204,579,207,580,581,482,220,356,618,617,384,612,240,122 | 3100,2760,2205,1473,257,2462,746,1419,828,388,1481,749,1725,612,2098,554,240,867,751,641,269,579,2546,312,259,2411,6,1049,617,139,122,1491,580,1609,618,1302,2468,220,2869,581,793,1611,204,905,1930,2583,482,870,2768,2223,2687,356,2630,2326,1379,62,3104,2118,207,960,538,189,814,1449,2248,396,1516,1390,1391,2937,2639,1337... | -1.6370929036029538,-0.7566787356245731,-0.32863839725396865,0.014906920281284118,1.1388686667807886,-0.5000305276776785,0.4458966875052482,0.043584231076383116,0.3883303529448472,0.8496631638098913,0.014906920281284118,0.4458966875052482,-0.0997257723165647,0.5611177432905115,-0.2714529942827711,0.6187714535547078,1.1... | 3,210 |
Metalloendopeptidase activity | 6 | 15 | 2.324053 | 0.020123 | P22695,Q10713,P78536,Q5JRX3,O75844,P42892 | Functions | GO Molecular function | msigdb_gomf | 129,159,168,100,294,212 | 1582,2399,294,1658,129,212,2038,168,159,100,2447,2330,595,916,400 | -0.042424588305331204,-0.4429266939583211,1.0231104921518903,-0.07107893462425983,1.660952980636015,1.2837036718300274,-0.24284976542710374,1.4867194622568927,1.5157445302511974,1.8644711387133321,-0.4714819228517013,-0.38579613781079947,0.5899410509488118,0.33079418522630977,0.8496631638098913 | 3,210 |
Lactic acidosis | 30 | 90 | 2.319094 | 0.02039 | P51970,Q9BUB7,O75879,Q4J6C6,Q9UMS0,Q8IUX1,P14854,O43676,Q10713,Q969Y2,Q6P4A7,Q70HW3,O75380,Q00325,Q99797,O60783,P12694,Q9HC21,P31040,O00217,Q8NI60,Q86Y39,O95299,Q5XKP0,Q9NP80,Q9H845,P12235,P40939,O75251,P00403 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 499,536,255,10,399,531,523,36,159,177,299,58,434,556,595,433,574,349,211,92,102,233,475,377,514,381,114,613,493,366 | 92,1894,668,36,2459,433,493,822,434,1768,255,475,366,1350,2501,2570,1414,2614,785,1197,980,1199,1716,2538,895,114,574,523,1040,1783,211,2266,613,1484,1597,1426,1917,3196,614,499,1733,1157,1297,2846,556,794,159,1797,2771,1798,2718,10,1375,2629,2049,2719,377,299,58,950,233,531,3144,2960,102,1261,177,2851,1634,595,1570,76... | 1.9517715396466142,-0.18562193543010477,0.5034926557472869,3.0612894149232734,-0.5000305276776785,0.7630278449071122,0.6764533068474775,0.3883303529448472,0.7630278449071122,-0.1283651722112755,1.1388686667807886,0.7053046416328677,0.8785548612321639,0.07226934763416325,-0.5285725638095914,-0.585637146978094,0.04358423... | 3,210 |
Respiratory chain complex iv | 8 | 11 | 2.309981 | 0.020889 | P22695,P15954,P14406,P20674,P14854,P09669,O00483,P00403 | Localization | GO Cellular component | msigdb_gocc | 129,414,44,495,523,714,668,366 | 668,366,714,1352,786,44,523,414,495,129,1426 | 0.5034926557472869,0.8785548612321639,0.47469099999317105,0.07226934763416325,0.41710978314444397,2.768680735877916,0.6476088916672819,0.7918996031387205,0.6764533068474775,1.660952980636015,0.043584231076383116 | 3,210 |
ribosomal protein | 41 | 124 | 2.299157 | 0.021496 | Q9Y2Q9,Q9H2W6,P61254,P18077,Q9BYC9,P46779,P30050,P47914,P62263,P62753,P62273,Q9UHA3,Q9BYD1,P42766,P50914,Q96A35,O60783,Q9Y3U8,P63220,P83881,P49207,P82912,Q96GC5,P62750,P62917,Q07020,P46776,P62910,Q6P1L8,P62888,P61353,P62857,P55769,P82914,O76021,P39023,Q9P015,P25398,P61247,P61927,P15880 | Functions | Panther Protein class | panther_protein_class | 265,396,6,257,538,641,388,269,152,290,40,568,189,554,312,62,433,471,203,204,579,78,207,580,581,482,240,220,356,618,617,253,110,372,607,612,384,119,616,122,368 | 433,607,3100,2760,2205,1588,979,1473,368,257,2462,746,2866,119,1419,828,388,1481,749,1725,866,612,2098,716,554,240,867,751,641,1485,642,2309,269,579,2546,312,1669,2411,110,991,616,6,1049,617,122,2766,1364,1209,2102,152,792,2897,40,1490,3020,1491,1210,580,290,1609,1927,904,2362,253,618,1302,2468,220,2869,581,793,203,185... | 0.7630278449071122,0.5611177432905115,-1.6370929036029538,-0.7566787356245731,-0.32863839725396865,-0.042424588305331204,0.27328873734257736,0.014906920281284118,0.8785548612321639,1.1388686667807886,-0.5000305276776785,0.4458966875052482,-0.8990449194071448,1.7481432606681047,0.043584231076383116,0.3883303529448472,0.... | 3,210 |
Cellular response to starvation | 41 | 92 | 2.2824 | 0.022466 | P35268,P46778,P61254,P18077,P84098,P46779,P30050,P61513,P47914,P46782,P62263,P62753,P62273,P62266,P63173,P42766,Q92616,P50914,Q9Y3U8,P63220,P83881,P49207,P27635,P62750,P62917,P20042,Q07020,P42677,P46776,P62910,P62888,P61353,P62857,P39019,P46777,P39023,P25398,P61247,P61927,P15880,P18621 | Processes and pathways | Reactome Pathways | msigdb_reactome | 749,751,6,257,905,641,388,139,269,642,152,290,40,792,793,554,850,312,471,203,204,579,828,580,581,341,482,716,240,220,618,617,253,866,867,612,119,616,122,368,746 | 1906,3100,2760,2205,978,1588,979,368,257,2462,746,341,2264,2940,2866,119,1419,828,388,1481,749,2097,1725,1663,866,612,2098,1203,1204,716,554,240,867,751,641,1485,642,2309,269,579,312,991,616,6,1049,617,2412,139,122,2766,1364,1209,2102,152,792,2897,40,1490,3020,1491,1210,580,290,1609,1927,904,2362,253,2581,618,1302,2468... | -0.18562193543010477,-1.6370929036029538,-0.7566787356245731,-0.32863839725396865,0.27328873734257736,-0.042424588305331204,0.27328873734257736,0.8785548612321639,1.1388686667807886,-0.5000305276776785,0.4458966875052482,0.9363578339004853,-0.3572206950736908,-1.0412640839639304,-0.8990449194071448,1.7481432606681047,0... | 3,210 |
Organelle inner membrane | 77 | 240 | 2.281616 | 0.022512 | P21912,Q69YU5,P51970,Q99595,P22570,Q9BUB7,O43772,Q9BYC9,Q9P0J0,Q9UG56,Q02127,Q9H2D1,Q8IUX1,P14854,Q15070,Q9Y584,Q9Y6C9,Q99720,O43676,O14949,P14406,Q9UDW1,Q9H9P8,Q9BUR5,Q9Y619,Q70HW3,Q96A35,Q9UBX3,P22830,P82912,Q9UDX5,O00217,Q14728,Q8NI60,P12235,P04818,P22695,Q5SNT2,Q9Y5J9,Q10713,P49748,Q9BYD1,Q8TAA5,Q96GC5,P31040,Q1473... | Localization | GO Cellular component | msigdb_gocc | 496,1,499,0,497,536,9,538,14,543,15,16,531,523,22,25,26,34,36,43,44,46,50,48,57,58,62,73,77,78,80,92,95,102,114,125,129,131,137,159,174,189,188,207,211,222,224,218,233,235,265,256,299,294,319,318,349,361,356,354,377,381,384,372,370,366,400,396,391,414,446,434,433,460,475,495,493 | 92,668,1463,43,521,36,9,2459,1710,1085,433,929,493,822,434,890,2399,1768,2756,1769,1088,294,2348,2201,1836,1348,1140,256,475,2988,2828,1470,366,1350,125,784,1840,1351,1091,1197,1473,2503,714,1352,2537,114,2539,825,786,44,523,2304,414,2092,1040,495,1982,496,497,129,77,2866,679,1289,1986,1783,211,218,899,1786,1044,460,22... | 1.9517715396466142,0.5034926557472869,0.014906920281284118,2.768680735877916,0.6476088916672819,3.0612894149232734,4.471263356608017,-0.5000305276776785,-0.0997257723165647,0.21581458325266947,0.7630278449071122,0.3020375859379114,0.6764533068474775,0.3883303529448472,0.7630278449071122,0.33079418522630977,-0.442926693... | 3,210 |
Sulfur compound transport | 8 | 12 | 2.275539 | 0.022874 | Q8TB61,Q9UBX3,O15439,Q9H0H5,O00400,Q9HC21,Q70HW3,P33527 | Processes and pathways | GO Biological process | msigdb_gobp | 169,73,13,274,321,349,58,151 | 321,1896,13,367,151,3187,795,58,169,274,349,73 | 0.9652690090027104,-0.18562193543010477,3.9415276975615496,0.8785548612321639,1.5447751873907711,-2.906871317124417,0.41710978314444397,2.5057048530603376,1.4867194622568927,1.1099198375930281,0.9363578339004853,2.243098964599965 | 3,210 |
Selenoamino acid metabolism | 44 | 93 | 2.272213 | 0.023074 | P35268,P46778,P61254,P18077,P84098,P62847,P46779,P30050,P61513,P47914,P46782,O43324,P62263,P62753,P62273,P62266,P63173,P42766,P50914,P23526,Q9Y3U8,P63220,P83881,P49207,P27635,P00390,P62750,P62917,Q07020,P42677,P46776,P62910,P57772,P62888,P61353,P62857,P39019,P46777,P39023,P25398,P61247,P61927,P15880,P18621 | Processes and pathways | Reactome Pathways | msigdb_reactome | 749,751,6,257,905,904,641,388,139,269,642,519,152,290,40,792,793,554,312,678,471,203,204,579,828,324,580,581,482,716,240,220,721,618,617,253,866,867,612,119,616,122,368,746 | 2939,519,324,3100,2760,2205,1090,1588,979,1979,368,257,2462,746,2866,678,119,1419,828,388,3124,1481,749,1725,866,612,2098,1787,716,554,240,867,751,641,1485,642,2309,2036,269,579,1206,312,903,1996,721,991,616,6,1049,617,139,122,2766,1364,1209,2102,152,792,2897,40,1490,3020,1491,1210,580,290,1609,1927,904,2362,253,2581,6... | -1.0412640839639304,0.6476088916672819,0.9652690090027104,-1.6370929036029538,-0.7566787356245731,-0.32863839725396865,0.21581458325266947,-0.042424588305331204,0.27328873734257736,-0.21423943402394552,0.8785548612321639,1.1388686667807886,-0.5000305276776785,0.4458966875052482,-0.8990449194071448,0.5034926557472869,1.... | 3,210 |
Regulation of epithelial cell migration | 11 | 45 | 2.270276 | 0.023191 | O75122,Q96E22,P78536,P23634,P42785,P61586,Q92766,Q8WTV0,O94813,Q9NQC3,P09601 | Processes and pathways | GO Biological process | msigdb_gobp | 65,336,168,70,76,229,445,19,118,285,239 | 1895,65,1239,118,2609,2204,1286,1840,1975,2650,1474,239,1659,2989,2913,70,1986,2542,1724,1204,76,2868,1298,1734,229,2845,438,2469,168,2367,1311,727,1313,802,803,19,445,336,2288,1753,3090,285,1274,1646,1647 | -0.18562193543010477,2.4181275560384297,0.12966331135686696,1.7481432606681047,-0.614159800319998,-0.32863839725396865,0.10096234789685095,-0.15699720383151142,-0.21423943402394552,-0.6426760976202697,0.014906920281284118,1.1967846271462892,-0.07107893462425983,-1.1549371513670597,-0.9843937111343767,2.3014229202036454... | 3,210 |
Ribosomal proteins | 44 | 130 | 2.269115 | 0.023261 | Q9Y2Q9,Q9H2W6,P61254,P18077,Q9BYC9,P46779,P30050,P61513,P47914,P62263,P62753,P62273,Q9UHA3,O95478,Q9BYD1,P42766,P50914,Q96A35,O60783,Q9Y3U8,P63220,P83881,P49207,P82912,Q96GC5,P62750,P62917,Q07020,P46776,P62910,Q6P1L8,P62888,P61353,P62857,P55769,P82914,O76021,P39023,Q9P015,P63244,P25398,P61247,P61927,P15880 | Functions | Protein Atlas Protein class | protein_atlas_protein_class | 265,396,6,257,538,641,388,139,269,152,290,40,568,550,189,554,312,62,433,471,203,204,579,78,207,580,581,482,240,220,356,618,617,253,110,372,607,612,384,242,119,616,122,368 | 433,607,550,3100,2760,2205,1588,979,1473,368,257,2462,746,2866,119,1419,828,388,1481,749,1725,866,612,2098,716,554,240,867,751,641,1485,642,2309,269,579,2546,312,1669,2411,110,991,616,6,1049,617,139,122,2766,1364,1209,2102,152,792,2897,40,1490,3020,1491,1210,580,290,1609,1927,904,2362,253,618,1302,2468,220,2869,581,793... | 0.7630278449071122,0.5611177432905115,0.6187714535547078,-1.6370929036029538,-0.7566787356245731,-0.32863839725396865,-0.042424588305331204,0.27328873734257736,0.014906920281284118,0.8785548612321639,1.1388686667807886,-0.5000305276776785,0.4458966875052482,-0.8990449194071448,1.7481432606681047,0.043584231076383116,0.... | 3,210 |
Dermal atrophy | 7 | 27 | 2.265774 | 0.023465 | Q8NCH0,Q9NWM8,Q15392,Q9H1A4,P22413,O75844,O00170 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 163,35,68,275,47,294,124 | 124,1193,294,1970,1532,639,1842,2865,1095,1535,47,1043,1722,715,1849,354,1855,1859,726,757,68,163,3142,533,275,35,1761 | 1.6900110425777688,0.1583723191033171,1.0231104921518903,-0.21423943402394552,-0.013762661187869209,0.532301591048701,-0.15699720383151142,-0.8990449194071448,0.21581458325266947,-0.013762661187869209,2.6809820839637393,0.24454771184920537,-0.0997257723165647,0.47469099999317105,-0.15699720383151142,0.9074531014169275,... | 3,210 |
Muscle adaptation | 8 | 18 | 2.265574 | 0.023477 | P25490,Q9Y5B0,P23634,P58546,Q14457,P16615,P09601,P49840 | Processes and pathways | GO Biological process | msigdb_gobp | 478,103,70,138,231,386,239,187 | 2757,712,1532,239,1035,2884,386,70,478,187,138,502,2517,2108,1794,1437,231,103 | -0.7566787356245731,0.47469099999317105,-0.013762661187869209,1.1967846271462892,0.24454771184920537,-0.9275003379149459,0.8496631638098913,2.3014229202036454,0.7053046416328677,1.399678167637441,1.602853122792676,0.6764533068474775,-0.5285725638095914,-0.2714529942827711,-0.1283651722112755,0.043584231076383116,1.2257... | 3,210 |
Organic acid transport | 15 | 45 | 2.265045 | 0.02351 | O14678,P08195,P53985,P08183,O43772,Q9UBX3,O15439,Q6P4A7,Q9H2D1,Q9BQT8,Q9NP80,Q9H2J7,Q9Y619,P33527,P50416 | Processes and pathways | GO Biological process | msigdb_gobp | 309,121,480,7,9,73,13,299,16,446,514,512,57,151,526 | 309,1896,13,9,605,546,1088,2892,2261,824,2204,894,1090,7,121,896,2913,679,1292,2969,2030,2895,935,151,3187,526,2653,480,942,795,2770,2280,299,729,1633,446,16,512,1755,2489,514,73,1820,3123,57 | 0.9941865778088491,-0.18562193543010477,3.9415276975615496,4.471263356608017,0.5611177432905115,0.6187714535547078,0.21581458325266947,-0.9559499207681041,-0.3572206950736908,0.3883303529448472,-0.32863839725396865,0.33079418522630977,0.21581458325266947,4.7070559039511,1.7190744805634337,0.33079418522630977,-0.9843937... | 3,210 |
Ventricular arrhythmia | 11 | 35 | 2.255536 | 0.0241 | O60783,P00403,O43772,Q96AX1,Q969Y2,P49748,P36551,P12235,P42892,P50402,P46976 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 433,366,9,508,177,174,460,114,212,370,219 | 9,433,822,2260,366,1532,1350,2649,1714,1589,1475,114,1659,1147,1590,496,679,460,936,3121,212,219,174,1155,2438,370,2318,1249,1114,3008,849,177,508,1875,1950 | 4.471263356608017,0.7630278449071122,0.3883303529448472,-0.3572206950736908,0.8785548612321639,-0.013762661187869209,0.07226934763416325,-0.6426760976202697,-0.0997257723165647,-0.042424588305331204,0.014906920281284118,1.7772173493984713,-0.07107893462425983,0.1870894267741931,-0.042424588305331204,0.6764533068474775,... | 3,210 |
Dehydrogenase | 16 | 59 | 2.231369 | 0.025657 | P21912,Q8TC12,Q8N4Q0,Q8NCN5,Q00796,Q8N8N7,Q9P0J0,Q02127,Q9H9P8,P40925,P00390,Q14914,P31040,O00217,O75251,P11766 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 496,302,197,75,329,141,14,15,50,296,324,86,211,92,493,494 | 92,2197,1408,493,822,2828,2681,1285,324,1350,1587,1142,1351,980,2884,494,1353,496,2028,1783,576,787,211,2464,296,1664,2684,643,3196,682,790,499,940,832,1363,1297,329,15,1367,1369,86,1059,2772,1861,3070,197,141,75,764,302,2794,2851,1634,50,1953,970,817,14,2562 | 1.9517715396466142,-0.32863839725396865,0.043584231076383116,0.6764533068474775,0.3883303529448472,-0.8421163995463957,-0.6711860899363502,0.10096234789685095,0.9652690090027104,0.07226934763416325,-0.042424588305331204,0.1870894267741931,0.07226934763416325,0.27328873734257736,-0.9275003379149459,0.6764533068474775,0.... | 3,210 |
Ire1alpha activates chaperones | 8 | 26 | 2.22309 | 0.02621 | Q969H8,Q9NWM8,O76024,O14773,P49748,P43307,P49840,O43909 | Processes and pathways | Reactome Pathways | msigdb_reactome | 423,35,350,267,174,85,187,432 | 267,432,350,893,1411,1532,1472,2544,85,174,187,2467,2412,1612,2930,2110,2550,1165,1066,423,565,35,1341,1829,1830,1345 | 1.1099198375930281,0.7630278449071122,0.9074531014169275,0.33079418522630977,0.043584231076383116,-0.013762661187869209,0.014906920281284118,-0.557108085715093,2.0682431353184825,1.4577000206031279,1.399678167637441,-0.5000305276776785,-0.4429266939583211,-0.042424588305331204,-1.0128317515561631,-0.2714529942827711,-0... | 3,210 |
Ribosomal protein | 55 | 123 | 2.212373 | 0.026941 | Q9Y2Q9,P35268,P46778,Q9H2W6,P61254,P18077,P84098,Q9BYC9,P46779,P30050,P61513,P47914,P46782,Q9BYD2,P62263,P62753,P62273,P62266,P63173,Q9BYD1,P42766,P50914,Q96A35,O60783,Q96EY7,Q9Y3U8,P63220,P83881,P49207,P82912,Q96GC5,P27635,P62750,P62917,Q8TAE8,Q07020,P42677,P46776,P62910,Q6P1L8,P62888,P61353,P62857,P82914,P39019,P4677... | Functions | Protein Atlas Molecular function | protein_atlas_molecular_function | 265,749,751,396,6,257,905,538,641,388,139,269,642,814,152,290,40,792,793,189,554,312,62,433,852,471,203,204,579,78,207,828,580,581,910,482,716,240,220,356,618,617,253,372,866,867,612,384,242,119,616,870,122,368,746 | 433,3100,2760,2205,1588,979,1473,368,257,2462,746,2866,119,1419,828,388,1481,749,1725,866,612,2098,716,554,240,867,751,641,1485,642,2309,269,579,2546,312,1669,2411,991,616,6,1049,617,139,122,2766,1364,1209,2102,152,792,2897,40,1490,3020,1491,1210,580,290,1609,1927,904,2362,253,618,1302,2468,220,2869,581,793,203,242,185... | 0.7630278449071122,-1.6370929036029538,-0.7566787356245731,-0.32863839725396865,-0.042424588305331204,0.27328873734257736,0.014906920281284118,0.8785548612321639,1.1388686667807886,-0.5000305276776785,0.4458966875052482,-0.8990449194071448,1.7481432606681047,0.043584231076383116,0.3883303529448472,0.8496631638098913,0.... | 3,210 |
Negative regulation of growth | 6 | 30 | 2.209174 | 0.027163 | Q9Y5B0,Q9P0J0,P22413,P63244,O94813,P49840 | Processes and pathways | GO Biological process | msigdb_gobp | 103,14,47,242,118,187 | 1134,1968,1768,118,712,639,2145,2864,2884,47,478,2574,1786,187,1731,939,242,1212,2848,2318,1252,2775,1562,2116,1744,2288,285,14,1705,103 | 0.1870894267741931,-0.21423943402394552,-0.1283651722112755,1.7481432606681047,0.47469099999317105,0.532301591048701,-0.30004918409410347,-0.8990449194071448,-0.9275003379149459,2.6809820839637393,0.7053046416328677,-0.585637146978094,-0.1283651722112755,1.399678167637441,-0.0997257723165647,0.3020375859379114,1.196784... | 3,210 |
Renal agenesis | 15 | 54 | 2.204161 | 0.027513 | Q15058,Q8WWQ0,Q15392,P61254,P18077,P62273,Q9UBM7,O43924,Q00534,P62857,P60953,Q96C36,P42766,Q86XL3,Q07020 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 421,198,68,6,257,40,191,71,619,253,270,406,554,223,482 | 1895,3027,2197,2459,71,1139,822,1588,1842,1148,257,2707,2574,1294,866,716,554,2150,867,2309,1363,991,270,6,1049,617,2766,1209,40,904,253,1302,2869,619,1553,482,421,68,1057,2444,2375,763,2419,1510,223,1115,198,406,768,1515,191,2923,2782,1964 | -0.18562193543010477,-1.2685220944449345,-0.32863839725396865,-0.5000305276776785,2.243098964599965,0.1870894267741931,0.3883303529448472,-0.042424588305331204,-0.15699720383151142,0.1870894267741931,1.1388686667807886,-0.6996898275229555,-0.585637146978094,0.10096234789685095,0.35955846414598713,0.47469099999317105,0.... | 3,210 |
U2 type spliceosomal complex | 20 | 58 | 2.200296 | 0.027786 | Q9NQ29,Q9Y333,Q6P2Q9,O60306,Q9Y383,O60508,P62316,Q15428,O60231,Q96DI7,P09234,P08621,Q9UBB9,O75533,P62314,O43172,Q9Y4Z0,O43660,P55769,Q9UNP9 | Localization | GO Cellular component | msigdb_gocc | 397,136,652,637,427,157,280,529,287,698,180,674,63,710,343,472,238,604,110,113 | 472,1191,1578,604,1580,287,637,157,1530,710,975,2141,1712,2706,674,180,1907,1537,1045,1425,110,1300,3049,343,280,1301,2104,1740,1308,2740,2659,2227,1213,1057,529,2958,2627,652,1682,2446,698,1877,1815,1453,397,1396,922,63,1343,1575,113,2753,136,427,1186,2342,238,777 | 0.7053046416328677,0.1583723191033171,-0.042424588305331204,0.5611177432905115,-0.042424588305331204,1.0520407045954674,0.532301591048701,1.5157445302511974,-0.013762661187869209,0.47469099999317105,0.27328873734257736,-0.30004918409410347,-0.0997257723165647,-0.6996898275229555,0.5034926557472869,1.428686242990915,-0.... | 3,210 |
er | 22 | 94 | 2.19602 | 0.02809 | Q9H6H4,Q9NQC3,O00264,Q8N4V1,P09132,Q86Y07,O60499,O96005,Q8NF37,O00767,Q86UL3,Q8NHH9,Q15392,Q9BRK0,O95470,O00400,Q14739,Q99640,Q9P2W9,Q9NPA0,Q06136,Q16850 | Localization | OpenCell Localization | opencell_localization | 276,285,149,30,33,292,288,42,301,173,315,317,68,338,323,321,222,90,107,382,115,127 | 149,321,173,3159,2754,603,1084,1835,635,288,1239,2024,3170,2892,1655,323,2988,42,1905,1713,930,1471,1472,33,1776,2094,640,1726,461,2833,1205,1046,2578,989,1156,869,833,1736,1920,753,1211,1551,836,115,483,2586,1932,2316,222,2991,3074,68,2444,2003,127,404,802,2374,2280,1509,315,292,30,1005,1067,301,317,657,3009,1869,2636... | 1.5447751873907711,0.9652690090027104,1.4577000206031279,-2.3435994424571596,-0.7566787356245731,0.5611177432905115,0.21581458325266947,-0.15699720383151142,0.532301591048701,1.0520407045954674,0.12966331135686696,-0.24284976542710374,-2.597271502186017,-0.9559499207681041,-0.07107893462425983,0.9652690090027104,-1.154... | 3,210 |
Lethargy | 34 | 84 | 2.187324 | 0.028719 | P61254,P18077,Q9UMS0,O43772,Q8IUX1,P50416,O43676,P62273,P49748,Q9Y619,P42766,P23786,O75380,O14678,P49770,P12694,P45954,Q13144,Q9HC21,O00217,P40818,P42677,Q07020,P25490,Q86Y39,Q9BU61,Q96EY8,P61353,P12235,P40939,P49821,P20674,P62857,O75251 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 6,257,399,9,531,526,36,40,174,57,554,679,434,309,201,574,578,725,349,92,715,716,482,478,233,768,510,617,114,613,614,495,253,493 | 2565,92,309,36,9,493,822,434,1768,1350,2501,2570,785,1588,980,2538,3111,114,574,257,1040,495,1241,2028,679,478,1243,1783,2465,866,715,613,3121,716,554,578,867,2309,174,201,614,526,2914,1157,1297,991,6,1049,617,2766,1209,40,904,253,1302,2869,482,725,1500,1312,2771,233,531,3144,1804,1261,2851,510,3182,767,1875,768,1755,3... | -0.585637146978094,1.9517715396466142,0.9941865778088491,3.0612894149232734,4.471263356608017,0.6764533068474775,0.3883303529448472,0.7630278449071122,-0.1283651722112755,0.07226934763416325,-0.5285725638095914,-0.585637146978094,0.41710978314444397,-0.042424588305331204,0.27328873734257736,-0.557108085715093,-1.778625... | 3,210 |
Ion transport by p type atpases | 7 | 11 | 2.182346 | 0.029084 | P05026,P23634,P54709,P16615,P20020,Q9HD20,P98194 | Processes and pathways | Reactome Pathways | msigdb_reactome | 476,70,167,386,458,155,723 | 713,476,386,458,70,1846,167,723,2108,1794,155 | 0.47469099999317105,0.7053046416328677,0.8496631638098913,0.7341628395132606,2.3014229202036454,-0.15699720383151142,1.4867194622568927,0.47469099999317105,-0.2714529942827711,-0.1283651722112755,1.5447751873907711 | 3,210 |
Aplasia hypoplasia of the skin | 10 | 54 | 2.182008 | 0.029109 | Q13126,Q8NCH0,Q9NWM8,Q15392,P53701,Q9H1A4,P22413,O75844,Q9Y619,O00170 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 89,163,35,68,354,275,47,294,57,124 | 124,1407,2495,1193,890,294,1140,1970,2802,1532,639,1976,1842,2090,1147,2865,1095,1535,2264,982,47,1043,1722,2353,2212,715,2356,1205,1849,354,1363,1925,1855,2585,558,89,686,1859,1251,2900,726,757,68,2055,163,3142,533,275,1951,408,35,1020,1761,57 | 1.6900110425777688,0.043584231076383116,-0.5285725638095914,0.1583723191033171,0.33079418522630977,1.0231104921518903,0.1870894267741931,-0.21423943402394552,-0.8136432086046264,-0.013762661187869209,0.532301591048701,-0.21423943402394552,-0.15699720383151142,-0.2714529942827711,0.1870894267741931,-0.8990449194071448,0... | 3,210 |
Abnormal blood glucose concentration | 28 | 94 | 2.168756 | 0.030101 | Q9Y2Q9,P22695,O43772,Q4J6C6,O75879,Q16134,Q8IUX1,P50416,Q08426,O43676,P49748,O75844,Q4G176,O75380,Q8WWQ0,P35610,O95470,P12694,P45954,O00217,P53985,P25490,Q9Y5B0,Q86Y39,Q5XKP0,Q9H845,P40939,O75251 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 265,129,9,10,255,391,531,526,29,36,174,294,441,434,198,437,323,574,578,92,480,478,103,233,377,381,613,493 | 2565,92,36,9,493,822,434,1768,294,255,2348,323,1285,1532,1350,2883,2501,2570,1414,980,2538,3111,895,574,1145,2304,1038,1040,129,679,1418,478,1783,2895,1358,437,2465,936,1295,2436,613,1203,1204,1484,578,3196,174,614,526,2216,1733,480,990,1157,1297,2513,835,29,1369,1054,391,2660,2771,441,10,377,1322,233,531,3144,1261,198... | -0.585637146978094,1.9517715396466142,3.0612894149232734,4.471263356608017,0.6764533068474775,0.3883303529448472,0.7630278449071122,-0.1283651722112755,1.0231104921518903,1.1388686667807886,-0.4143647846958465,0.9652690090027104,0.10096234789685095,-0.013762661187869209,0.07226934763416325,-0.9275003379149459,-0.528572... | 3,210 |
Porphyrin containing compound metabolic process | 6 | 19 | 2.168637 | 0.03011 | P22830,P30519,P09601,O00264,P33527,P30536 | Processes and pathways | GO Biological process | msigdb_gobp | 77,186,239,149,151,94 | 149,929,1973,1714,239,77,1355,186,94,151,460,2438,832,2719,2377,319,2823,2491,1961 | 1.5447751873907711,0.3020375859379114,-0.21423943402394552,-0.0997257723165647,1.1967846271462892,2.1556490854488635,0.07226934763416325,1.399678167637441,1.9517715396466142,1.5447751873907711,0.7341628395132606,-0.4714819228517013,0.3883303529448472,-0.6996898275229555,-0.4143647846958465,0.9941865778088491,-0.8136432... | 3,210 |
Decreased activity of mitochondrial complex i | 13 | 38 | 2.166572 | 0.030267 | P51970,Q86Y39,O43676,Q99757,O95298,Q9UBX3,Q969Y2,Q9H845,Q9Y584,Q70HW3,O75380,O00217,O75251 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 499,233,36,360,256,73,177,381,25,58,434,92,493 | 92,36,493,822,434,1768,256,1350,1040,1783,1597,614,499,2411,1733,1297,2629,2719,58,233,531,3144,1261,177,2851,852,1947,360,768,2487,1120,381,3155,1339,73,2458,25,1346 | 1.9517715396466142,3.0612894149232734,0.6764533068474775,0.3883303529448472,0.7630278449071122,-0.1283651722112755,1.1388686667807886,0.07226934763416325,0.24454771184920537,-0.1283651722112755,-0.042424588305331204,0.5611177432905115,0.6764533068474775,-0.4429266939583211,-0.0997257723165647,0.10096234789685095,-0.614... | 3,210 |
Aerobic respiration | 21 | 83 | 2.156723 | 0.031027 | P21912,P22695,O95298,Q15070,O43676,P15954,O14949,P14406,Q9UDW1,P40925,P30405,O75380,P31040,O00217,P31930,Q9H3K2,O95299,P61586,P20674,O75251,P00403 | Processes and pathways | GO Biological process | msigdb_gobp | 496,129,256,22,36,414,43,44,46,296,181,434,211,92,218,361,475,229,495,493,366 | 92,668,43,36,1408,1710,493,822,434,1409,1768,3128,2201,1836,256,475,366,1350,1974,1840,2614,785,1197,980,1199,1352,1716,786,44,1476,1658,2304,414,1040,495,1149,496,129,1289,1986,1783,181,1539,211,218,3187,899,2805,1044,1483,296,1664,2213,1426,3048,3138,614,682,499,1733,869,791,555,1297,229,794,1369,22,2277,1059,1681,23... | 1.9517715396466142,0.5034926557472869,2.768680735877916,3.0612894149232734,0.043584231076383116,-0.0997257723165647,0.6764533068474775,0.3883303529448472,0.7630278449071122,0.043584231076383116,-0.1283651722112755,-1.9483080573558453,-0.32863839725396865,-0.15699720383151142,1.1388686667807886,0.7053046416328677,0.8785... | 3,210 |
Ion transmembrane transport | 48 | 151 | 2.144009 | 0.032032 | Q9UHG3,Q9Y4W6,Q04917,P08183,O43772,O15439,P16615,Q9H2D1,P14854,Q9HD20,Q8IUH4,P42858,P33527,Q8N4V1,P54709,Q14847,Q8TB61,Q9Y277,Q9UDW1,Q6P4A7,Q06787,Q4KMQ2,Q9BQT8,O60831,O75844,P30405,Q8WWC4,Q9Y619,Q70HW3,P56385,O00299,P27695,P23634,Q9UBX3,O00400,P20020,Q9HC21,Q14728,P31930,P53985,P05026,P07384,P20674,Q9H2J7,P12235,P0819... | Processes and pathways | GO Biological process | msigdb_gobp | 2,400,134,7,9,13,386,16,523,155,282,525,151,30,167,559,169,570,46,299,558,298,446,546,294,181,318,57,58,555,428,436,70,73,321,458,349,95,218,480,476,352,495,512,114,121,493,366 | 428,321,668,1896,13,1579,9,605,1651,889,546,929,744,493,2399,1088,294,2892,2201,1836,1140,673,366,713,476,931,784,894,1840,2612,352,1091,2147,7,121,1197,2863,1352,2884,114,2539,786,523,386,2865,2989,458,495,2264,2940,982,2306,70,1289,1986,436,1479,181,1846,2030,218,151,1596,1044,2097,1663,525,3019,2151,2270,1426,3048,2... | 0.7630278449071122,0.9652690090027104,0.5034926557472869,-0.18562193543010477,3.9415276975615496,-0.042424588305331204,4.471263356608017,0.5611177432905115,-0.07107893462425983,0.33079418522630977,0.6187714535547078,0.3020375859379114,0.4458966875052482,0.6764533068474775,-0.4429266939583211,0.21581458325266947,1.02311... | 3,210 |
Ribosomal subunit | 41 | 123 | 2.135577 | 0.032714 | Q9Y2Q9,P51116,P61254,P18077,Q9H2W6,Q9BYC9,P46779,P30050,P61513,P47914,P62263,P62753,P62273,Q9BYD1,P42766,P50914,Q96A35,O60783,Q9Y3U8,P63220,P83881,P49207,P82912,Q96GC5,P62750,P62917,Q07020,P46776,P62910,Q6P1L8,P62888,P61353,P62857,P82914,P39023,Q9P015,P63244,P25398,P61247,P61927,P15880 | Localization | GO Cellular component | msigdb_gocc | 265,259,6,257,396,538,641,388,139,269,152,290,40,189,554,312,62,433,471,203,204,579,78,207,580,581,482,240,220,356,618,617,253,372,612,384,242,119,616,122,368 | 433,1906,3100,2760,2205,1588,979,1473,368,257,2462,746,2866,119,1419,828,388,1481,749,1725,866,612,2098,716,554,240,867,751,641,1485,642,2309,269,579,2546,312,259,1669,2411,991,616,6,1049,617,139,122,2766,1364,1209,2102,152,792,2897,40,1490,3020,1491,1210,580,290,1609,1927,904,2362,253,618,1302,2468,220,2869,581,793,20... | 0.7630278449071122,-0.18562193543010477,-1.6370929036029538,-0.7566787356245731,-0.32863839725396865,-0.042424588305331204,0.27328873734257736,0.014906920281284118,0.8785548612321639,1.1388686667807886,-0.5000305276776785,0.4458966875052482,-0.8990449194071448,1.7481432606681047,0.043584231076383116,0.3883303529448472,... | 3,210 |
Atpase coupled transmembrane transporter activity | 10 | 26 | 2.134975 | 0.032763 | O14678,P23634,P08183,Q15388,O15439,P16615,P20020,Q9HD20,Q9NRK6,P33527 | Functions | GO Molecular function | msigdb_gomf | 309,70,7,355,13,386,458,155,319,151 | 309,13,929,713,476,1840,7,386,458,2264,2940,70,1292,151,3187,2097,1663,2412,723,1247,2887,355,155,319,1891,2824 | 0.9941865778088491,3.9415276975615496,0.3020375859379114,0.47469099999317105,0.7053046416328677,-0.15699720383151142,4.7070559039511,0.8496631638098913,0.7341628395132606,-0.3572206950736908,-1.0412640839639304,2.3014229202036454,0.10096234789685095,1.5447751873907711,-2.906871317124417,-0.2714529942827711,-0.071078934... | 3,210 |
Protein peptidyl prolyl isomerization | 7 | 26 | 2.12305 | 0.03375 | Q9Y680,Q9NWM8,Q9H2H8,Q9UNP9,P26885,P30405,O00170 | Processes and pathways | GO Biological process | msigdb_gobp | 194,35,133,113,53,181,124 | 124,888,1983,53,181,2788,2034,988,1737,2620,2655,724,2366,2714,403,2047,1555,2004,284,3129,133,35,113,2389,2342,194 | 1.6900110425777688,0.33079418522630977,-0.21423943402394552,2.593323246131426,1.428686242990915,-0.78516400280081,-0.24284976542710374,0.27328873734257736,-0.0997257723165647,-0.614159800319998,-0.6426760976202697,0.47469099999317105,-0.4143647846958465,-0.6996898275229555,0.8207780604161526,-0.24284976542710374,-0.013... | 3,210 |
Organophosphate ester transport | 11 | 27 | 2.122074 | 0.033831 | P08183,Q8TB61,O15439,Q9H2D1,Q4KMQ2,Q99808,Q8WTV0,O00400,P12235,P33527,P61916 | Processes and pathways | GO Biological process | msigdb_gobp | 7,169,13,16,298,208,19,321,114,151,278 | 321,13,605,3162,784,7,114,2539,1288,747,151,3187,1543,278,1853,3115,298,728,621,169,19,208,3141,3147,16,349,2071 | 0.9652690090027104,3.9415276975615496,0.5611177432905115,-2.42819419723944,0.41710978314444397,4.7070559039511,1.7772173493984713,-0.557108085715093,0.10096234789685095,0.4458966875052482,1.5447751873907711,-2.906871317124417,-0.013762661187869209,1.0809771684172826,-0.15699720383151142,-1.778625708526751,1.02311049215... | 3,210 |
Abnormal cardiac ventricular function | 7 | 22 | 2.108416 | 0.034995 | Q15233,Q969Y2,P49748,P22413,O75844,P12235,P31040 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 205,177,174,47,294,114,211 | 294,2400,366,3162,1532,1350,980,1475,114,496,47,211,1784,2150,174,1616,906,205,2551,177,1875,2019 | 1.0231104921518903,-0.4429266939583211,0.8785548612321639,-2.42819419723944,-0.013762661187869209,0.07226934763416325,0.27328873734257736,0.014906920281284118,1.7772173493984713,0.6764533068474775,2.6809820839637393,1.2837036718300274,-0.1283651722112755,-0.30004918409410347,1.4577000206031279,-0.042424588305331204,0.3... | 3,210 |
Abnormal erythrocyte enzyme level | 8 | 22 | 2.096585 | 0.03603 | P61254,P18077,P62273,P62857,Q96RL7,P00813,P42766,Q07020 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 6,257,40,253,304,351,554,482 | 351,1588,257,866,716,554,867,2309,991,1102,6,1049,617,2766,1209,40,904,253,1302,2869,482,304 | 0.9074531014169275,-0.042424588305331204,1.1388686667807886,0.35955846414598713,0.47469099999317105,0.6187714535547078,0.35955846414598713,-0.38579613781079947,0.27328873734257736,0.21581458325266947,4.736544775086076,0.24454771184920537,0.5611177432905115,-0.7566787356245731,0.1583723191033171,2.8856731513793363,0.330... | 3,210 |
metalloprotease | 8 | 27 | 2.082494 | 0.037297 | P22695,P31930,Q10713,P53582,Q5JRX3,O75844,P42892,Q7Z2K6 | Functions | Panther Protein class | panther_protein_class | 129,218,159,39,100,294,212,162 | 1582,2399,294,1469,2758,2090,1658,129,1422,218,212,2038,39,3043,159,100,2813,162,2171,2330,595,916,1517,2253,920,3026,400 | -0.042424588305331204,-0.4429266939583211,1.0231104921518903,0.014906920281284118,-0.7566787356245731,-0.2714529942827711,-0.07107893462425983,1.660952980636015,0.043584231076383116,1.254724699862172,1.2837036718300274,-0.24284976542710374,2.8856731513793363,-1.2969048468084008,1.5157445302511974,1.8644711387133321,-0.... | 3,210 |
Cellular respiration | 23 | 100 | 2.063989 | 0.039019 | P21912,P22695,O95298,Q16134,Q15070,O43676,P15954,O14949,P14406,Q9UDW1,P40925,P30405,O75380,P31040,O00217,P31930,Q9H3K2,O95299,P61586,Q9NZ45,P20674,O75251,P00403 | Processes and pathways | GO Biological process | msigdb_gobp | 496,129,256,391,22,36,414,43,44,46,296,181,434,211,92,218,361,475,229,515,495,493,366 | 92,668,43,36,2459,1408,1710,493,822,434,1409,1768,1088,3128,2201,1836,256,475,366,1350,1972,2401,1974,1840,2614,785,1197,980,1199,1352,1716,786,1145,44,1476,1658,2304,414,1040,495,1149,496,129,1289,1986,1783,181,1539,211,218,3187,899,2805,1044,1483,1295,296,1664,2213,2684,1426,3048,3138,614,682,499,1733,869,791,555,129... | 1.9517715396466142,0.5034926557472869,2.768680735877916,3.0612894149232734,-0.5000305276776785,0.043584231076383116,-0.0997257723165647,0.6764533068474775,0.3883303529448472,0.7630278449071122,0.043584231076383116,-0.1283651722112755,0.21581458325266947,-1.9483080573558453,-0.32863839725396865,-0.15699720383151142,1.13... | 3,210 |
Regulation of muscle adaptation | 7 | 17 | 2.061665 | 0.03924 | P25490,Q9Y5B0,P23634,P58546,Q14457,P16615,P49840 | Processes and pathways | GO Biological process | msigdb_gobp | 478,103,70,138,231,386,187 | 2757,712,1532,1035,2884,386,70,478,187,138,502,2517,2108,1794,1437,231,103 | -0.7566787356245731,0.47469099999317105,-0.013762661187869209,0.24454771184920537,-0.9275003379149459,0.8496631638098913,2.3014229202036454,0.7053046416328677,1.399678167637441,1.602853122792676,0.6764533068474775,-0.5285725638095914,-0.2714529942827711,-0.1283651722112755,0.043584231076383116,1.2257516709181544,1.8644... | 3,210 |
External side of plasma membrane | 6 | 22 | 2.06009 | 0.03939 | P08183,O96005,O15439,P00390,Q13740,P42892 | Localization | GO Cellular component | msigdb_gocc | 7,42,13,324,54,212 | 13,891,1410,42,324,351,3162,2758,2204,894,609,7,2736,1658,575,2542,212,1916,3109,54,1437,1505 | 3.9415276975615496,0.33079418522630977,0.043584231076383116,2.827168320227334,0.9652690090027104,0.9074531014169275,-2.42819419723944,-0.7566787356245731,-0.32863839725396865,0.33079418522630977,0.5611177432905115,4.7070559039511,-0.7281873598507694,-0.07107893462425983,0.5899410509488118,-0.557108085715093,1.283703671... | 3,210 |
Hormone metabolic process | 6 | 27 | 2.05032 | 0.040333 | Q8TC12,Q8NBN7,O75844,P42892,Q9UBM7,P30536 | Processes and pathways | GO Biological process | msigdb_gobp | 302,235,294,212,191,94 | 2086,891,294,323,713,1658,1416,1148,94,212,643,1296,1553,2370,2479,1801,235,1380,302,2794,2242,1634,2016,1953,191,1079,2255 | -0.2714529942827711,0.33079418522630977,1.0231104921518903,0.9652690090027104,0.47469099999317105,-0.07107893462425983,0.043584231076383116,0.1870894267741931,1.9517715396466142,1.2837036718300274,0.532301591048701,0.10096234789685095,-0.013762661187869209,-0.4143647846958465,-0.5000305276776785,-0.1283651722112755,1.2... | 3,210 |
Abnormal number of erythroid precursors | 11 | 26 | 2.049737 | 0.04039 | P61254,P18077,P62273,P61353,P62857,P04637,P42766,O75533,P62263,Q86SX6,Q07020 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 6,257,40,617,253,639,554,710,152,623,482 | 710,2611,639,1973,1588,257,866,716,554,867,2309,991,6,1049,617,2766,1209,152,40,904,253,1302,2869,482,623,1188 | 0.47469099999317105,-0.614159800319998,0.532301591048701,-0.21423943402394552,-0.042424588305331204,1.1388686667807886,0.35955846414598713,0.47469099999317105,0.6187714535547078,0.35955846414598713,-0.38579613781079947,0.27328873734257736,4.736544775086076,0.24454771184920537,0.5611177432905115,-0.7566787356245731,0.15... | 3,210 |
Endothelial cell migration | 7 | 36 | 2.049276 | 0.040435 | P23634,P78536,P42785,P61586,Q8WTV0,O94813,P09601 | Processes and pathways | GO Biological process | msigdb_gobp | 70,168,76,229,19,118,239 | 1895,1239,118,2204,1286,894,1840,1975,1474,239,1659,2989,2913,70,1986,2542,1152,2998,76,989,2868,1298,229,438,2469,168,2367,1313,1505,585,802,19,336,2288,1753,1274 | -0.18562193543010477,0.12966331135686696,1.7481432606681047,-0.32863839725396865,0.10096234789685095,0.33079418522630977,-0.15699720383151142,-0.21423943402394552,0.014906920281284118,1.1967846271462892,-0.07107893462425983,-1.1549371513670597,-0.9843937111343767,2.3014229202036454,-0.21423943402394552,-0.5571080857150... | 3,210 |
Cytoplasmic ribosomal proteins | 39 | 77 | 2.018508 | 0.043538 | P35268,P46778,P61254,P18077,P84098,P46779,P30050,P61513,P47914,P46782,P62263,P62753,P62273,P62266,P63173,P42766,P50914,Q9Y3U8,P63220,P83881,P49207,P27635,P62750,P62917,Q07020,P42677,P46776,P62910,P62888,P61353,P62857,P39019,P46777,P39023,P25398,P61247,P61927,P15880,P18621 | Processes and pathways | WikiPathways | msigdb_wp | 749,751,6,257,905,641,388,139,269,642,152,290,40,792,793,554,312,471,203,204,579,828,580,581,482,716,240,220,618,617,253,866,867,612,119,616,122,368,746 | 3100,2760,2205,1588,979,368,257,2462,746,2866,119,1419,828,388,1481,749,1725,866,612,2098,716,554,240,867,751,641,1485,642,2309,269,579,2546,312,3177,991,616,6,1049,617,139,122,2766,1364,1209,2102,152,792,2897,40,1490,3020,1491,1210,580,290,1609,1927,904,2362,253,2581,618,1302,2468,220,2869,581,793,203,1611,204,905,193... | -1.6370929036029538,-0.7566787356245731,-0.32863839725396865,-0.042424588305331204,0.27328873734257736,0.8785548612321639,1.1388686667807886,-0.5000305276776785,0.4458966875052482,-0.8990449194071448,1.7481432606681047,0.043584231076383116,0.3883303529448472,0.8496631638098913,0.014906920281284118,0.4458966875052482,-0... | 3,210 |
Response to oxygen levels | 21 | 64 | 2.01787 | 0.043605 | Q96A26,P04637,Q8N511,Q13526,Q5SSJ5,P52789,P78536,O95352,P30519,Q9NQ88,Q92544,Q99808,P17655,O94966,P05026,Q99757,P00813,P61586,Q14457,P07237,P09601 | Processes and pathways | GO Biological process | msigdb_gobp | 4,639,18,403,689,527,168,179,186,598,206,208,575,322,476,360,351,229,231,609,239 | 1234,2343,1579,822,782,322,179,2828,1412,351,1532,2758,2401,639,476,2145,609,239,2461,575,1981,1535,2913,677,186,1539,2266,1663,1204,2355,2509,1916,2868,527,3043,2412,229,168,1855,403,231,2160,1056,3000,689,907,1004,18,1869,206,2904,4,2288,2242,1327,360,208,2125,598,2909,1079,1763,1830,1130 | 0.12966331135686696,-0.4143647846958465,-0.042424588305331204,0.3883303529448472,0.41710978314444397,0.9652690090027104,1.428686242990915,-0.8421163995463957,0.043584231076383116,0.9074531014169275,-0.013762661187869209,-0.7566787356245731,-0.4429266939583211,0.532301591048701,0.7053046416328677,-0.30004918409410347,0.... | 3,210 |
Protein targeting to membrane | 10 | 35 | 2.014147 | 0.043994 | P09132,Q9UHB9,O60725,P49458,Q9UL54,O43681,Q15629,P43307,A5D8V6,P56589 | Processes and pathways | GO Biological process | msigdb_gobp | 33,665,104,353,108,636,116,85,250,528 | 250,1235,2195,636,2731,104,1837,1472,33,2543,2895,900,2437,85,1789,353,1668,528,833,1736,2361,645,1673,116,2112,2236,1257,1567,1333,2335,1960,665,2075,108,1233 | 1.1678236113059064,0.12966331135686696,-0.32863839725396865,0.532301591048701,-0.7281873598507694,1.8353813208718948,-0.15699720383151142,0.014906920281284118,3.1784500806866625,-0.557108085715093,-0.9559499207681041,0.33079418522630977,-0.4714819228517013,2.0682431353184825,-0.1283651722112755,0.9074531014169275,-0.07... | 3,210 |
Ribosomal large subunit biogenesis | 21 | 60 | 2.00048 | 0.045448 | P61254,P18077,Q9BYC9,Q9Y221,Q9GZL7,Q9NUL7,Q9BZE4,Q8IY81,Q9UHA3,O00541,O75683,O95478,P42766,P50914,O60287,P62750,Q5SY16,P55769,O76021,P39023,Q9H7B2 | Processes and pathways | GO Biological process | msigdb_gobp | 6,257,538,544,407,286,426,695,568,545,671,550,554,312,310,580,344,110,607,612,254 | 545,925,310,671,607,550,2205,1976,257,2462,828,612,554,681,867,312,110,1546,6,1491,580,2468,2869,793,1611,2583,2476,2321,344,2687,1003,2688,695,1807,1692,1814,538,1449,1177,426,407,254,2699,1181,969,286,1123,1886,2454,1756,1020,1520,2909,568,1184,544,2188,2391,1026,2190 | 0.6187714535547078,0.3020375859379114,0.9941865778088491,0.5034926557472869,0.5611177432905115,0.6187714535547078,-0.32863839725396865,-0.21423943402394552,1.1388686667807886,-0.5000305276776785,0.3883303529448472,0.5611177432905115,0.6187714535547078,0.5034926557472869,0.35955846414598713,0.9941865778088491,1.80629671... | 3,210 |
Mitochondrial electron transport nadh to ubiquinone | 8 | 22 | 1.999065 | 0.045601 | P51970,O43676,O95299,O95298,P49821,O75380,O00217,O75251 | Processes and pathways | GO Biological process | msigdb_gobp | 499,36,475,256,614,434,92,493 | 92,668,36,1710,493,822,434,1768,256,475,1350,980,1040,1783,614,499,1297,2277,1059,2818,1120,1346 | 1.9517715396466142,0.5034926557472869,3.0612894149232734,-0.0997257723165647,0.6764533068474775,0.3883303529448472,0.7630278449071122,-0.1283651722112755,1.1388686667807886,0.7053046416328677,0.07226934763416325,0.27328873734257736,0.24454771184920537,-0.1283651722112755,0.5611177432905115,0.6764533068474775,0.10096234... | 3,210 |
Lipid homeostasis | 9 | 30 | 1.997663 | 0.045753 | Q9BWH2,O15260,Q9HCL2,Q5BJF2,O15254,Q8WTV0,Q9NQC3,Q9Y6C9,P61916 | Processes and pathways | GO Biological process | msigdb_gobp | 339,99,236,8,144,19,285,26,278 | 1134,862,144,99,1141,3162,2207,1722,3187,437,278,796,998,8,2551,2552,1168,2283,19,2746,336,2288,339,1701,236,514,285,3099,2336,26 | 0.1870894267741931,0.35955846414598713,1.5738113969759262,1.8644711387133321,0.1870894267741931,-2.42819419723944,-0.32863839725396865,-0.0997257723165647,-2.906871317124417,0.7630278449071122,1.0809771684172826,0.41710978314444397,0.27328873734257736,4.55966070066017,-0.557108085715093,-0.557108085715093,0.18708942677... | 3,210 |
Abnormal hemoglobin | 13 | 26 | 1.987492 | 0.046868 | P42677,Q9UKG1,P61254,P18077,P62273,P62847,P61353,P62857,Q96MF7,P39019,P46777,P42766,Q07020 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 716,881,6,257,40,904,617,253,273,866,867,554,482 | 890,1713,1588,257,866,716,554,2150,867,2309,991,1736,6,1049,617,2766,1209,40,904,253,1302,2869,482,273,881,2186 | 0.33079418522630977,-0.0997257723165647,-0.042424588305331204,1.1388686667807886,0.35955846414598713,0.47469099999317105,0.6187714535547078,-0.30004918409410347,0.35955846414598713,-0.38579613781079947,0.27328873734257736,-0.0997257723165647,4.736544775086076,0.24454771184920537,0.5611177432905115,-0.7566787356245731,0... | 3,210 |
Receptor | 8 | 41 | 1.983712 | 0.047288 | Q99720,Q9NZT2,Q9NS69,P35613,Q8WTV0,P24390,O00264,Q9Y2I1 | Functions | Protein Atlas Molecular function | protein_atlas_molecular_function | 34,72,12,81,19,150,149,64 | 149,2345,862,603,891,3162,2758,2883,894,1974,1472,979,2864,2736,3149,1658,3085,369,150,2030,81,2898,1162,3115,1437,2160,222,1252,19,2011,336,1174,1327,34,12,72,924,64,859,1345,2799 | 1.5447751873907711,-0.4143647846958465,0.35955846414598713,0.5611177432905115,0.33079418522630977,-2.42819419723944,-0.7566787356245731,-0.9275003379149459,0.33079418522630977,-0.21423943402394552,0.014906920281284118,0.27328873734257736,-0.8990449194071448,-0.7281873598507694,-2.202522941644554,-0.07107893462425983,-1... | 3,210 |
Complex i biogenesis | 10 | 28 | 1.978212 | 0.047905 | P51970,Q86Y39,O43676,O95299,O95298,Q9P0J0,Q9H845,O75380,O00217,O75251 | Processes and pathways | Reactome Pathways | msigdb_reactome | 499,233,36,475,256,14,381,434,92,493 | 92,36,1710,493,822,434,1768,256,475,1350,1040,1783,614,499,1297,2277,1059,233,531,3144,1261,1693,768,381,3155,1339,14,1346 | 1.9517715396466142,3.0612894149232734,-0.0997257723165647,0.6764533068474775,0.3883303529448472,0.7630278449071122,-0.1283651722112755,1.1388686667807886,0.7053046416328677,0.07226934763416325,0.24454771184920537,-0.1283651722112755,0.5611177432905115,0.6764533068474775,0.10096234789685095,-0.3572206950736908,0.2445477... | 3,210 |
P-type ATPases | 6 | 7 | 1.970446 | 0.048787 | P05026,P23634,P54709,P16615,P98194,P20020 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 476,70,167,386,723,458 | 713,476,386,458,70,167,723 | 0.47469099999317105,0.7053046416328677,0.8496631638098913,0.7341628395132606,2.3014229202036454,1.4867194622568927,0.47469099999317105 | 3,210 |
Lipid transporter activity | 6 | 21 | 1.968979 | 0.048956 | P08183,O15439,Q4KMQ2,P33527,P61916,P30536 | Functions | GO Molecular function | msigdb_gomf | 7,13,298,151,278,94 | 309,862,13,7,1980,1288,1292,94,151,3187,1543,278,1853,298,2280,621,957,2120,1331,3147,467 | 0.9941865778088491,0.35955846414598713,3.9415276975615496,4.7070559039511,-0.21423943402394552,0.10096234789685095,0.10096234789685095,1.9517715396466142,1.5447751873907711,-2.906871317124417,-0.013762661187869209,1.0809771684172826,-0.15699720383151142,1.0231104921518903,-0.3572206950736908,0.5611177432905115,0.302037... | 3,210 |
Rac1 gtpase cycle | 15 | 44 | 1.965452 | 0.049362 | Q86Y07,Q14155,P63000,P63167,Q9H0H5,P60953,Q9UQB8,Q68EM7,O15498,Q13112,P50402,P42166,P42167,Q9Y2I1,Q14739 | Processes and pathways | Reactome Pathways | msigdb_reactome | 292,160,438,241,274,270,453,153,518,582,370,342,680,64,222 | 2825,518,1771,823,2758,894,342,680,2035,370,1601,2101,270,438,241,2586,582,2106,2046,160,1311,1250,222,2003,1679,153,2552,1862,2553,954,292,1866,1115,733,873,1946,961,274,2177,1228,453,1024,64,1761 | -0.8421163995463957,0.6476088916672819,-0.1283651722112755,0.3883303529448472,-0.7566787356245731,0.33079418522630977,0.9363578339004853,0.5034926557472869,-0.24284976542710374,0.8785548612321639,-0.042424588305331204,-0.2714529942827711,1.1099198375930281,0.7630278449071122,1.1967846271462892,-0.585637146978094,0.5899... | 3,210 |
reductase | 9 | 29 | 1.964746 | 0.049444 | Q15392,Q9H7Z7,Q9UDW1,Q8N8N7,P00390,Q06136,Q14914,Q14739,Q9UBM7 | Functions | Panther Protein class | panther_protein_class | 68,306,46,141,324,115,86,222,191 | 2257,2757,1531,2803,1713,324,1971,552,2304,1416,3143,1242,1355,2095,2353,984,115,222,86,68,2772,2918,623,141,406,306,2561,191,46 | -0.3572206950736908,-0.7566787356245731,-0.013762661187869209,-0.8136432086046264,-0.0997257723165647,0.9652690090027104,-0.21423943402394552,0.6187714535547078,-0.38579613781079947,0.043584231076383116,-2.1178248450474757,0.12966331135686696,0.07226934763416325,-0.2714529942827711,-0.4143647846958465,0.273288737342577... | 3,210 |
HAD superfamily [IPR023214] | 8 | 19 | 1.963506 | 0.049587 | Q9Y5B0,P23634,P16615,P20020,Q9HD20,P98194,Q8NFW8,Q5TFE4 | Sequence | InterPro Superfamily | interpro_homologous_superfamily | 103,70,386,458,155,723,56,690 | 2192,713,386,458,70,1544,723,1215,690,56,911,1631,2922,2796,1699,1881,1227,155,103 | -0.32863839725396865,0.47469099999317105,0.8496631638098913,0.7341628395132606,2.3014229202036454,-0.013762661187869209,0.47469099999317105,0.1583723191033171,0.5034926557472869,2.564112589516673,0.33079418522630977,-0.042424588305331204,-0.9843937111343767,-0.78516400280081,-0.07107893462425983,-0.15699720383151142,0.... | 3,210 |
HAD-like superfamily [IPR036412] | 8 | 19 | 1.963506 | 0.049587 | Q9Y5B0,P23634,P16615,P20020,Q9HD20,P98194,Q8NFW8,Q5TFE4 | Sequence | InterPro Superfamily | interpro_homologous_superfamily | 103,70,386,458,155,723,56,690 | 2192,713,386,458,70,1544,723,1215,690,56,911,1631,2922,2796,1699,1881,1227,155,103 | -0.32863839725396865,0.47469099999317105,0.8496631638098913,0.7341628395132606,2.3014229202036454,-0.013762661187869209,0.47469099999317105,0.1583723191033171,0.5034926557472869,2.564112589516673,0.33079418522630977,-0.042424588305331204,-0.9843937111343767,-0.78516400280081,-0.07107893462425983,-0.15699720383151142,0.... | 3,210 |
Tissue migration | 11 | 55 | 1.962409 | 0.049715 | O75122,Q96E22,P78536,P23634,P42785,P61586,Q92766,Q8WTV0,O94813,Q9NQC3,P09601 | Processes and pathways | GO Biological process | msigdb_gobp | 65,336,168,70,76,229,445,19,118,285,239 | 1895,65,1239,118,2609,2204,1286,894,1840,1975,2650,1474,239,1659,2989,2913,70,1986,2542,1724,1152,2998,1204,76,989,2868,1298,1734,229,2845,438,2469,168,1553,2517,2367,1311,727,2003,1313,1505,585,802,803,19,445,336,2288,1753,3090,285,878,1274,1646,1647 | -0.18562193543010477,2.4181275560384297,0.12966331135686696,1.7481432606681047,-0.614159800319998,-0.32863839725396865,0.10096234789685095,0.33079418522630977,-0.15699720383151142,-0.21423943402394552,-0.6426760976202697,0.014906920281284118,1.1967846271462892,-0.07107893462425983,-1.1549371513670597,-0.984393711134376... | 3,210 |
Sphingolipid de novo biosynthesis | 6 | 11 | 2.438547 | 0.014746 | P51648,Q06136,O95470,Q96G23,P27544,O15121 | Processes and pathways | Reactome Pathways | msigdb_reactome | 37,199,101,73,208,26 | 26,278,1710,1772,101,1487,208,37,199,73,1648 | 3.0239793639306813,1.401134087308939,-0.1964126828419297,-0.22634804876060674,2.0870284690553733,-0.06395305747605311,1.630770150005915,2.822510997047098,1.661241829099701,2.2685902357175696,-0.15185455240937126 | 3,210 |
Sphingolipid metabolism integrated pathway | 6 | 9 | 2.419475 | 0.015543 | Q16739,Q06136,O95470,Q96G23,P27544,O15121 | Processes and pathways | WikiPathways | msigdb_wp | 33,199,101,73,208,26 | 26,278,1710,101,208,199,666,33,73 | 3.0239793639306813,1.401134087308939,-0.1964126828419297,2.0870284690553733,1.630770150005915,1.661241829099701,0.6498584271230965,2.90102584126154,2.2685902357175696 | 3,210 |
Sphingolipid metabolism overview | 6 | 9 | 2.419475 | 0.015543 | Q16739,Q06136,O95470,Q96G23,P27544,O15121 | Processes and pathways | WikiPathways | msigdb_wp | 33,199,101,73,208,26 | 26,278,1710,101,208,199,666,33,73 | 3.0239793639306813,1.401134087308939,-0.1964126828419297,2.0870284690553733,1.630770150005915,1.661241829099701,0.6498584271230965,2.90102584126154,2.2685902357175696 | 3,210 |
Sphingolipid metabolism | 7 | 10 | 2.355147 | 0.018515 | P04062,Q16739,P17900,Q06136,O95470,P07602,O15269 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 126,33,103,199,101,52,278 | 278,1710,101,126,52,103,199,666,33,326 | 1.401134087308939,-0.1964126828419297,2.0870284690553733,1.9746479174832445,2.5954221021396817,2.0870284690553733,1.661241829099701,0.6498584271230965,2.90102584126154,1.2710445729919746 | 3,210 |
Regulation of lysosomal lumen ph | 6 | 7 | 2.241854 | 0.024971 | Q9HC07,Q8N511,P50897,Q9NWW5,O75503,O75787 | Processes and pathways | GO Biological process | msigdb_gobp | 97,13,138,431,210,446 | 210,446,138,13,603,97,431 | 1.6205693247136275,0.9880603023396407,1.917441041803686,3.2893663916259843,0.7366749914819102,2.1055017317691553,1.0344802841599925 | 3,210 |
Cristae formation | 8 | 9 | 2.225201 | 0.026068 | Q9BUR5,O95202,Q6UXV4,Q5XKP0,Q9Y512,Q9NX63,Q9Y4W6,Q16891 | Processes and pathways | GO Biological process | msigdb_gobp | 131,356,296,175,307,507,416,318 | 356,318,175,296,131,591,507,416,307 | 1.204643279521078,1.2820220819729822,1.7515006919655713,1.347361260466732,1.955655640787987,0.7611934819569155,0.881937017334852,1.069001611287548,1.3256809556487925 | 3,210 |
Intermediate filament, rod domain [IPR039008] | 7 | 8 | 2.160089 | 0.030766 | Q16352,P20700,P07197,P48681,P08670,Q03252,P07196 | Sequence | InterPro Domain | interpro_domain | 195,513,294,549,109,436,118 | 647,118,294,109,513,549,436,195 | 0.6748240642101201,2.0124054126852844,1.347361260466732,2.049864066587316,0.858030796157992,0.8098570200405039,1.0229175049605006,1.6713557593392439 | 3,210 |
Intermediate filament protein, conserved site [IPR018039] | 7 | 8 | 2.160089 | 0.030766 | Q16352,P20700,P07197,P48681,P08670,Q03252,P07196 | Sequence | InterPro Conserved site | interpro_conserved_site | 195,513,294,549,109,436,118 | 647,118,294,109,513,549,436,195 | 0.6748240642101201,2.0124054126852844,1.347361260466732,2.049864066587316,0.858030796157992,0.8098570200405039,1.0229175049605006,1.6713557593392439 | 3,210 |
Intrinsic component of golgi membrane | 7 | 10 | 2.112281 | 0.034662 | Q9Y282,Q969X5,O95070,L0R6Q1,O15258,O43505,Q8TB61 | Localization | GO Cellular component | msigdb_gocc | 146,406,211,181,343,253,94 | 181,343,253,211,509,1025,957,94,406,146 | 1.7315909829794818,1.2268799582772898,1.4859266544772944,1.6205693247136275,0.8699988396202327,0.2588974772737941,0.326307106439725,2.1239031058014124,1.0918779578760416,1.907839023170101 | 3,210 |
Endoplasmic reticulum tubular network organization | 7 | 12 | 2.094929 | 0.036177 | Q9H6H4,Q9BRK0,Q6NUK4,O95197,Q9NQC3,Q8NHH9,P57088 | Processes and pathways | GO Biological process | msigdb_gobp | 227,420,113,20,29,158,413 | 20,413,459,872,113,158,420,1350,1056,227,1763,29 | 3.1585531831086073,1.069001611287548,0.9529469707603657,0.41912045171734913,2.0311718054537344,1.8595348542432146,1.0575222062488734,0.022375928201394484,0.23166690476374294,1.569234054047289,-0.21135718574042264,2.9552150269553397 | 3,210 |
Cytochrome complex assembly | 7 | 12 | 2.06201 | 0.039207 | Q9BSK2,P53701,Q6DKK2,Q15070,O75880,Q69YU5,Q9Y2R0 | Processes and pathways | GO Biological process | msigdb_gobp | 39,361,365,18,275,24,95 | 670,275,1429,361,18,24,365,404,762,39,1800,95 | 0.6373266801028631,1.411816152011253,-0.03500473434976105,1.193485935738,3.20256521186496,3.07677395656104,1.182302430096535,1.0918779578760416,0.5358760637885005,2.7907337531247736,-0.22634804876060674,2.1147113706663596 | 3,210 |
Nucleotide transmembrane transport | 7 | 8 | 2.053193 | 0.040054 | Q9H2D1,P12235,Q9BSK2,P05141,P12236,O15439,Q8TB61 | Processes and pathways | GO Biological process | msigdb_gobp | 4,162,39,686,558,530,94 | 530,714,686,162,558,94,39,4 | 0.8340045251873066,0.586869580596862,0.6247620912906596,1.84007448351757,0.7977374297619025,2.1239031058014124,2.7907337531247736,3.836509503264616 | 3,210 |
ATP-binding cassette transporter family | 6 | 9 | 2.052114 | 0.040159 | Q03518,O75027,P08183,Q03519,O15439,P33897 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 384,482,389,535,530,191 | 530,482,389,623,1410,191,384,535,1141 | 0.8340045251873066,0.9175738044692829,1.1373043723370269,0.6996603267996259,-0.020595446965442143,1.6814481915121122,1.1485937357921607,0.8340045251873066,0.16290875045406936 | 3,210 |
Abc type transporter activity | 8 | 11 | 2.051427 | 0.040225 | Q03518,O75027,P08183,Q9HD20,Q03519,O15439,O14678,P33897 | Functions | GO Molecular function | msigdb_gomf | 384,482,389,81,535,530,565,191 | 565,530,482,389,623,1410,191,384,535,81,1141 | 0.7855870788576451,0.8340045251873066,0.9175738044692829,1.1373043723370269,0.6996603267996259,-0.020595446965442143,1.6814481915121122,1.1485937357921607,0.8340045251873066,2.232831781149459,0.16290875045406936 | 3,210 |
Ceramide biosynthetic process | 6 | 10 | 2.049711 | 0.040393 | P04062,Q16739,Q96G23,P27544,O15269,O15121 | Processes and pathways | GO Biological process | msigdb_gobp | 126,33,73,208,278,26 | 26,278,1710,126,208,666,33,403,73,711 | 3.0239793639306813,1.401134087308939,-0.1964126828419297,1.9746479174832445,1.630770150005915,0.6498584271230965,2.90102584126154,1.0918779578760416,2.2685902357175696,0.5995337121866889 | 3,210 |
ABC transporter type 1, transmembrane domain superfamily [IPR036640] | 7 | 10 | 2.046212 | 0.040736 | Q03518,O75027,P08183,Q03519,O15439,O14678,P33897 | Sequence | InterPro Superfamily | interpro_homologous_superfamily | 384,482,389,535,530,565,191 | 565,530,482,389,623,1410,191,384,535,1141 | 0.7855870788576451,0.8340045251873066,0.9175738044692829,1.1373043723370269,0.6996603267996259,-0.020595446965442143,1.6814481915121122,1.1485937357921607,0.8340045251873066,0.16290875045406936 | 3,210 |
Abc transporters | 7 | 10 | 2.046212 | 0.040736 | Q03518,O75027,P08183,Q03519,O15439,O14678,P33897 | Processes and pathways | KEGG Pathways | msigdb_kegg | 384,482,389,535,530,565,191 | 565,530,482,389,623,1410,191,384,535,1141 | 0.7855870788576451,0.8340045251873066,0.9175738044692829,1.1373043723370269,0.6996603267996259,-0.020595446965442143,1.6814481915121122,1.1485937357921607,0.8340045251873066,0.16290875045406936 | 3,210 |
ABC transporter type 1, transmembrane domain [IPR011527] | 7 | 10 | 2.046212 | 0.040736 | Q03518,O75027,P08183,Q03519,O15439,O14678,P33897 | Sequence | InterPro Domain | interpro_domain | 384,482,389,535,530,565,191 | 565,530,482,389,623,1410,191,384,535,1141 | 0.7855870788576451,0.8340045251873066,0.9175738044692829,1.1373043723370269,0.6996603267996259,-0.020595446965442143,1.6814481915121122,1.1485937357921607,0.8340045251873066,0.16290875045406936 | 3,210 |
Mitochondrial nucleotide transporter subfamily | 8 | 9 | 2.036337 | 0.041717 | Q9H2D1,P12235,Q9HC21,Q70HW3,Q9BSK2,Q6NUK1,P05141,P12236 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 4,162,260,66,39,657,686,558 | 714,686,162,558,657,66,39,4,260 | 0.586869580596862,0.6247620912906596,1.84007448351757,0.7977374297619025,0.6623574997738125,2.356818953824768,2.7907337531247736,3.836509503264616,1.47540985761985 | 3,210 |
Sphingolipid biosynthetic process | 9 | 15 | 2.029405 | 0.042417 | P04062,Q16739,Q06136,O95470,Q96G23,Q9P035,P27544,O15269,O15121 | Processes and pathways | GO Biological process | msigdb_gobp | 126,33,199,101,73,205,208,278,26 | 26,278,1710,101,126,1487,208,199,666,33,403,73,711,205,1648 | 3.0239793639306813,1.401134087308939,-0.1964126828419297,2.0870284690553733,1.9746479174832445,-0.06395305747605311,1.630770150005915,1.661241829099701,0.6498584271230965,2.90102584126154,1.0918779578760416,2.2685902357175696,0.5995337121866889,1.6409491149908735,-0.15185455240937126 | 3,210 |
Tetrapyrrole binding | 9 | 16 | 2.029083 | 0.04245 | Q9H7Z7,O43169,P09601,P53701,Q16850,O00264,Q6UW02,P30519,O15173 | Functions | GO Molecular function | msigdb_gomf | 325,38,40,361,107,51,57,28,62 | 51,62,38,1022,40,1923,28,361,107,57,404,1587,752,864,325,1259 | 2.5954221021396817,2.3916536040933773,2.7907337531247736,0.2588974772737941,2.7747641575162865,-0.3020077268703407,2.9859015171477754,1.193485935738,2.0684827664895757,2.5200380278463603,1.0918779578760416,-0.12237587478854399,0.5486753421710154,0.4322343646319835,1.2710445729919746,0.07908178905132351 | 3,210 |
calmodulin-related | 6 | 10 | 2.020505 | 0.043331 | Q9BPX6,P80303,Q02818,Q9BRK5,O43852,Q14257 | Functions | Panther Protein class | panther_protein_class | 448,6,47,177,116,151 | 116,1684,796,6,47,151,982,515,448,177 | 2.021797911431073,-0.18151426057096084,0.49727213928344227,3.798111606892421,2.6777899964295577,1.8789156496265464,0.29945651967751274,0.858030796157992,0.9880603023396407,1.7515006919655713 | 3,210 |
Class i peroxisomal membrane protein import | 9 | 10 | 2.01958 | 0.043427 | P33897,Q8NBU5,P51648,O75381,Q5T8D3,Q9NR77,P28288,P40855,P56589 | Processes and pathways | Reactome Pathways | msigdb_reactome | 191,654,37,136,139,77,623,122,383 | 714,136,623,191,122,37,383,139,654,77 | 0.586869580596862,1.927023636429267,0.6996603267996259,1.6814481915121122,2.0029942368825533,2.822510997047098,1.1485937357921607,1.917441041803686,0.6748240642101201,2.241796812015894 | 3,210 |
Endoplasmic reticulum tubular network | 7 | 13 | 1.983538 | 0.047307 | Q9H6H4,Q9BRK0,Q6NUK4,Q00765,P50402,Q9NQC3,Q8NHH9 | Localization | GO Cellular component | msigdb_gocc | 227,420,113,375,148,29,158 | 148,459,375,1321,2189,872,113,158,420,1350,227,1763,29 | 1.8885764048992375,0.9529469707603657,1.1598564515736667,0.036615047711478665,-0.4412506789391867,0.41912045171734913,2.0311718054537344,1.8595348542432146,1.0575222062488734,0.022375928201394484,1.569234054047289,-0.21135718574042264,2.9552150269553397 | 3,210 |
Protein transmembrane transporter activity | 8 | 11 | 1.967118 | 0.04917 | Q9NS69,Q9UGP8,Q99595,Q9Y584,P49755,Q07820,Q15388,O14925 | Functions | GO Molecular function | msigdb_gomf | 5,261,2,10,394,551,153,213 | 213,684,585,394,2077,551,153,2,5,261,10 | 1.6103465471343246,0.6247620912906596,0.7611934819569155,1.1146452073437958,-0.3788698240801004,0.8098570200405039,1.8789156496265464,3.836509503264616,3.836509503264616,1.47540985761985,3.506414357386638 | 3,210 |
Sphingolipid metabolism | 6 | 13 | 1.960049 | 0.04999 | P04062,Q16739,Q06136,O95470,O15269,O15121 | Processes and pathways | KEGG Pathways | msigdb_kegg | 126,33,199,101,278,26 | 26,278,1710,344,101,126,1571,1573,1740,199,666,33,711 | 3.0239793639306813,1.401134087308939,-0.1964126828419297,1.2268799582772898,2.0870284690553733,1.9746479174832445,-0.12237587478854399,-0.12237587478854399,-0.21135718574042264,1.661241829099701,0.6498584271230965,2.90102584126154,0.5995337121866889 | 3,210 |
Dysostosis multiplex | 6 | 7 | 2.462649 | 0.013791 | P54802,O00754,P04066,P10619,P15586,P16278 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 130,164,139,55,275,90 | 164,139,55,275,90,130,377 | 1.6551989417094066,1.7728328396449533,2.834506313368406,1.1254012693689186,2.2702148607681574,1.8555928595462654,0.9195049394408159 | 3,210 |
Sphingolipid metabolism integrated pathway | 6 | 9 | 2.454054 | 0.014126 | Q96G23,O15121,Q06136,Q13510,Q16739,O95470 | Processes and pathways | WikiPathways | msigdb_wp | 97,102,106,49,19,115 | 102,773,2542,115,165,106,49,19,97 | 2.145323291693078,0.44482842599710637,-0.6132162563523244,1.9859063385694156,1.6551989417094066,2.097891708372181,2.9477642917536246,3.770570742927153,2.176761289713973 | 3,210 |
Sphingolipid metabolism overview | 6 | 9 | 2.454054 | 0.014126 | Q96G23,O15121,Q06136,Q13510,Q16739,O95470 | Processes and pathways | WikiPathways | msigdb_wp | 97,102,106,49,19,115 | 102,773,2542,115,165,106,49,19,97 | 2.145323291693078,0.44482842599710637,-0.6132162563523244,1.9859063385694156,1.6551989417094066,2.097891708372181,2.9477642917536246,3.770570742927153,2.176761289713973 | 3,210 |
Sphingolipid metabolism | 6 | 10 | 2.420215 | 0.015511 | Q06136,P04062,P17900,Q13510,Q16739,P07602 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 106,44,76,49,19,83 | 773,2542,115,44,83,76,106,49,19,701 | 0.44482842599710637,-0.6132162563523244,1.9859063385694156,3.1143760455387404,2.347130772218854,2.4834554092716568,2.097891708372181,2.9477642917536246,3.770570742927153,0.526570177938448 | 3,210 |
Membrane lipid catabolic process | 8 | 11 | 2.409877 | 0.015958 | P06865,P50897,P06280,P04062,P04066,P17900,Q13510,O95470 | Processes and pathways | GO Biological process | msigdb_gobp | 225,35,201,44,139,76,49,115 | 115,44,139,201,225,2035,76,35,49,295,1246 | 1.9859063385694156,3.1143760455387404,1.7728328396449533,1.4484838393625152,1.3425958796740627,-0.3237426380487701,2.4834554092716568,3.27725211222102,2.9477642917536246,1.0884659720501764,0.1060924308462119 | 3,210 |
Sphingolipid metabolism in senescence | 6 | 12 | 2.201997 | 0.027666 | Q96G23,O15121,P04062,Q13510,Q16739,P16278 | Processes and pathways | WikiPathways | msigdb_wp | 97,102,44,49,19,90 | 102,773,44,310,90,1082,811,709,106,49,19,97 | 2.145323291693078,0.44482842599710637,3.1143760455387404,1.0513121178447833,2.2702148607681574,0.19262663846354372,0.4035341298811554,0.5062390987652113,2.097891708372181,2.9477642917536246,3.770570742927153,2.176761289713973 | 3,210 |
Sphingolipid metabolism | 7 | 13 | 2.054456 | 0.039932 | O15121,Q06136,P04062,Q13510,Q16739,O95470,P16278 | Processes and pathways | KEGG Pathways | msigdb_kegg | 102,106,44,49,19,115,90 | 102,773,2542,417,115,44,201,2700,90,106,49,19,1246 | 2.145323291693078,0.44482842599710637,-0.6132162563523244,0.8429102209698677,1.9859063385694156,3.1143760455387404,1.4484838393625152,-0.7384963885381698,2.2702148607681574,2.097891708372181,2.9477642917536246,3.770570742927153,0.1060924308462119 | 3,210 |
Sphingolipid biosynthetic process | 7 | 15 | 2.051214 | 0.040246 | Q96G23,O15121,Q06136,P04062,Q13510,Q16739,O95470 | Processes and pathways | GO Biological process | msigdb_gobp | 97,102,106,44,49,19,115 | 102,773,2542,115,44,2040,165,106,49,19,1608,97,1246,505,2491 | 2.145323291693078,0.44482842599710637,-0.6132162563523244,1.9859063385694156,3.1143760455387404,-0.3237426380487701,1.6551989417094066,2.097891708372181,2.9477642917536246,3.770570742927153,-0.09347842149372354,2.176761289713973,0.1060924308462119,0.7262001044800472,-0.5639012970998747 | 3,210 |
Glycosphingolipid metabolism | 8 | 17 | 1.963234 | 0.049619 | P06280,P04062,P17900,Q13510,P07602,Q16739,P10619,P16278 | Processes and pathways | Reactome Pathways | msigdb_reactome | 201,44,76,49,83,19,55,90 | 1536,417,44,201,225,83,2035,55,2700,90,76,49,19,2770,1619,1246,1580 | -0.07095809716865134,0.8429102209698677,3.1143760455387404,1.4484838393625152,1.3425958796740627,2.347130772218854,-0.3237426380487701,2.834506313368406,-0.7384963885381698,2.2702148607681574,2.4834554092716568,2.9477642917536246,3.770570742927153,-0.7894335101320087,-0.09347842149372354,0.1060924308462119,-0.070958097... | 3,210 |
Ion transmembrane transporter activity | 33 | 100 | 3.653146 | 0.000259 | Q9H2D1,P33527,P53985,P21796,P16615,Q14847,O00299,Q99808,Q9HD20,Q8TB61,Q8N4V1,O00400,Q9UBX3,Q6P4A7,P45880,Q70HW3,Q9Y619,O43772,O75964,Q93050,Q9UDW1,P00403,P12235,P31930,P23634,P14854,O43681,O75947,Q8N1S5,Q9Y277,Q8IUH4,P20674,P13073 | Functions | GO Molecular function | msigdb_gomf | 1,267,145,19,397,279,275,156,28,163,168,43,50,440,52,55,59,66,67,459,75,334,467,220,219,229,104,479,112,506,374,498,370 | 275,43,565,1867,104,66,2134,2050,479,67,2016,334,734,2416,2180,2993,2212,2274,2080,823,3142,1873,467,2686,370,229,397,1875,498,2339,3160,19,219,1318,3037,2083,220,267,2343,2571,2084,52,2383,3113,3048,2445,145,1658,1841,1500,1622,2960,2732,887,775,1504,2395,801,279,1048,3184,2671,1200,440,55,1237,374,112,168,1330,163,23... | 1.1487666995177788,2.687053265961324,0.6884687739263295,-0.1787578934323262,1.9387760747315386,2.311381403119757,-0.3543756565400391,-0.28808392260207233,0.7862799512775219,2.311381403119757,-0.2661038286652666,1.016858162020565,0.5297381122387874,-0.5338093246549072,-0.37659150480827835,-1.2202811138168626,-0.39886739... | 3,210 |
transporter | 11 | 57 | 3.569631 | 0.000357 | Q99595,Q9H2D1,O43772,Q9NR77,O43681,Q9Y584,Q15070,P53985,Q9HD45,Q9Y619,Q99808 | Functions | Panther Protein class | panther_protein_class | 0,1,66,136,104,13,45,145,26,59,156 | 1781,1185,1566,3112,2248,2132,937,104,66,1063,1486,2271,2306,2381,2661,1263,1584,3063,2423,1983,2445,145,2385,2028,2960,2449,1588,1589,45,3184,2950,1267,677,3080,1475,2288,1903,212,956,1964,2291,893,0,156,2491,1445,1,3070,624,26,136,2005,1216,2624,13,1914,59 | -0.13542382527329797,0.20352212550695528,-0.028051602989249587,-1.785701460422968,-0.42120377836259065,-0.3543756565400391,0.36813874070508046,1.9387760747315386,2.311381403119757,0.286217363258279,0.014520145426408674,-0.44360111347426245,-0.46605986346971,-0.5111634909229179,-0.740532149740219,0.16187790183882575,-0.... | 3,210 |
SLC superfamily of solute carriers | 12 | 43 | 3.492122 | 0.000479 | Q9H2D1,O43772,Q9BSK2,O00400,Q8N1S5,P53985,Q9UBX3,Q7L0J3,Q70HW3,Q9Y619,Q99808,Q9Y6C9 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 1,66,9,43,112,145,50,84,55,59,156,29 | 43,66,2134,2050,2016,2180,2080,467,2686,2083,2445,145,1658,887,775,3184,2671,1200,55,84,3147,112,163,2202,2357,526,156,1937,9,2902,1,1772,3070,1941,1969,560,746,686,50,2877,59,29,2760 | 2.687053265961324,2.311381403119757,-0.3543756565400391,-0.28808392260207233,-0.2661038286652666,-0.37659150480827835,-0.31012230394858126,0.8057169414204521,-0.7638342514312623,-0.31012230394858126,-0.556518486029154,1.6588461750842975,-0.0708373510934119,0.40881543685910227,0.4896128041999829,-2.7908471566158775,-0.7... | 3,210 |
Mitochondrial carrier domain superfamily [IPR023395] | 6 | 22 | 3.462163 | 0.000536 | Q9H2D1,Q9BSK2,Q9UBX3,Q70HW3,Q9Y619,Q9Y6C9 | Sequence | InterPro Superfamily | interpro_homologous_superfamily | 1,9,50,55,59,29 | 66,2134,2050,2180,467,2686,2445,887,775,2671,55,2202,1937,9,1,1941,746,686,50,2877,59,29 | 2.311381403119757,-0.3543756565400391,-0.28808392260207233,-0.37659150480827835,0.8057169414204521,-0.7638342514312623,-0.556518486029154,0.40881543685910227,0.4896128041999829,-0.740532149740219,2.4599952437757544,-0.37659150480827835,-0.20050904201939973,4.268651553761713,5.424065052068769,-0.20050904201939973,0.5297... | 3,210 |
SLC25 family of mitochondrial transporters | 6 | 22 | 3.462163 | 0.000536 | Q9H2D1,Q9BSK2,Q9UBX3,Q70HW3,Q9Y619,Q9Y6C9 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 1,9,50,55,59,29 | 66,2134,2050,2180,467,2686,2445,887,775,2671,55,2202,1937,9,1,1941,746,686,50,2877,59,29 | 2.311381403119757,-0.3543756565400391,-0.28808392260207233,-0.37659150480827835,0.8057169414204521,-0.7638342514312623,-0.556518486029154,0.40881543685910227,0.4896128041999829,-0.740532149740219,2.4599952437757544,-0.37659150480827835,-0.20050904201939973,4.268651553761713,5.424065052068769,-0.20050904201939973,0.5297... | 3,210 |
Mitochondrial substrate/solute carrier [IPR018108] | 6 | 22 | 3.462163 | 0.000536 | Q9H2D1,Q9BSK2,Q9UBX3,Q70HW3,Q9Y619,Q9Y6C9 | Sequence | InterPro Repeat | interpro_repeat | 1,9,50,55,59,29 | 66,2134,2050,2180,467,2686,2445,887,775,2671,55,2202,1937,9,1,1941,746,686,50,2877,59,29 | 2.311381403119757,-0.3543756565400391,-0.28808392260207233,-0.37659150480827835,0.8057169414204521,-0.7638342514312623,-0.556518486029154,0.40881543685910227,0.4896128041999829,-0.740532149740219,2.4599952437757544,-0.37659150480827835,-0.20050904201939973,4.268651553761713,5.424065052068769,-0.20050904201939973,0.5297... | 3,210 |
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