term
stringlengths
2
121
overlap
int64
6
281
setsize
int64
7
499
score
float64
1.96
10.6
pval
float64
0
0.05
edge
stringlengths
41
1.97k
type
stringclasses
5 values
subtype
stringclasses
24 values
subtype_key
stringclasses
24 values
edge_idxs
stringlengths
11
1.17k
ann_idxs
stringlengths
19
2.31k
ann_vals
stringlengths
124
9.94k
sig_size
int64
2.2k
3.73k
Mitochondrial substrate/solute carrier [IPR018108]
12
19
2.921662
0.003482
Q9NZJ7,Q70HW3,P12236,Q6NUK1,Q9BQT8,Q02978,Q9H2D1,Q9Y619,Q9Y6C9,Q9HC21,O43772,Q9UBX3
Sequence
InterPro Repeat
interpro_repeat
98,5,261,387,77,271,48,119,153,350,89,59
89,586,861,487,864,261,607,975,271,387,5,77,48,350,98,59,430,119,153
2.2964854074361383,0.34515985407120203,0.11708504290317308,0.46553808003374114,0.11708504290317308,0.9635371984080219,0.3278265608377056,0.06358895367080376,0.9311961834886229,0.6179160419293773,5.017262595389153,2.5440011741485096,3.110074180270112,0.7014420888364408,2.226542769012561,2.8641358146662417,0.567416931821...
2,812
Receptor
11
34
2.918625
0.003516
Q9Y5M8,Q9NS69,O15173,Q8WTV0,Q99720,Q14739,P35613,O00264,O15118,P15260,Q14108
Functions
Protein Atlas Molecular function
protein_atlas_molecular_function
66,2,36,67,135,235,121,118,56,185,62
118,56,36,2536,1081,455,1350,2363,925,1537,1084,566,2635,693,185,2569,386,121,2594,2722,825,62,235,611,612,67,1518,1952,248,135,2,2114,66,2329
1.8832252764522284,2.916446962695746,3.498161016050837,-0.762027572092384,0.009759382165723819,0.5166255731433357,-0.11716687434726772,-0.6058241514720926,0.08145780404230812,-0.1905472446215371,0.009759382165723819,0.37972336891623004,-0.9211896151418975,0.24063844353304098,1.3582082159271402,-0.801535746199426,0.6179...
2,812
Ion transport
69
187
2.917916
0.003524
P20020,P07602,Q70HW3,Q7KZN9,Q9UHG3,Q9Y4W6,P12236,Q6NUK1,Q8NE01,Q4KMQ2,Q01650,P30536,Q02978,P16615,P45880,P13073,P47985,P42858,Q9Y4C2,P21796,P51809,P78417,P56385,P33527,O75964,Q9Y277,O15173,Q14728,Q9UNH7,Q9UJS0,P61421,Q6P4A7,Q9H2D1,O14936,O43681,P24539,O75844,Q9UBX3,Q9HD20,P05023,P36543,Q9UDW1,Q15041,P30825,P56134,P0818...
Processes and pathways
GO Biological process
msigdb_gobp
257,132,5,133,7,526,261,387,267,522,520,14,271,144,17,146,147,275,409,23,397,414,413,411,34,164,36,163,431,430,424,46,48,299,182,435,57,59,60,184,313,64,195,386,447,71,77,79,465,467,90,89,248,92,350,476,98,226,227,495,239,112,487,242,510,119,122,511,125
2769,807,465,1679,1680,299,36,182,1846,89,586,476,997,691,1583,1276,1392,1486,2533,861,57,1034,598,34,227,92,768,590,2536,1111,1236,184,467,487,1081,1440,843,2312,1921,132,1082,71,924,723,1156,2688,863,602,864,261,146,964,638,144,1113,2158,2751,257,1239,673,694,674,2538,1924,23,435,1086,2160,2210,2289,904,1591,14,867,3...
-1.6338631244210937,0.15256614703595497,0.49962950681326135,-0.2459980349044931,-0.2459980349044931,0.8334597491992295,3.498161016050837,1.373639236931527,-0.3204965379073243,2.2964854074361383,0.34515985407120203,0.48260039141735633,0.04568305057423946,0.24063844353304098,-0.2089909446401189,-0.0807106708667228,-0.135...
2,812
Dementia
18
56
2.907028
0.003649
Q9Y487,Q9Y287,O76024,P07602,Q92889,P03886,Q9NZJ7,P54886,P17900,P42858,Q13510,O43681,P04062,O15118,Q5JTZ9,Q9NQZ5,P36543,Q14108
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
3,193,227,132,322,100,98,332,270,275,85,182,55,56,187,341,313,62
465,1342,56,182,343,2077,227,768,590,100,55,842,2680,132,2041,1780,270,1442,410,1587,1969,2252,847,744,313,1314,275,1786,2435,332,932,2509,1936,2542,876,1249,85,62,1058,187,1901,1137,707,322,943,1988,2610,2139,341,98,716,1957,1809,193,2590,3
0.49962950681326135,-0.11716687434726772,2.916446962695746,1.373639236931527,0.7014420888364408,-0.4334795450313125,1.1235025176038205,0.18790247626968237,0.34515985407120203,2.1984168906874886,2.9684696908889308,0.13484377635600422,-1.0425811965372063,1.7510917082093325,-0.41454454507068694,-0.283166031185393,0.931196...
2,812
primary active transporter
8
21
2.9063
0.003657
Q9NS69,Q9BUN8,Q6P4A7,O60888,P16615,O75381,P05023,Q8N4H5
Functions
Panther Protein class
panther_protein_class
2,136,46,109,144,145,184,29
109,145,528,768,184,467,1190,144,257,1697,348,611,46,29,1947,834,136,987,760,785,2
2.0421722903154036,1.661926099494074,0.4141504853427531,0.18790247626968237,1.3582082159271402,0.49962950681326135,-0.044408450650093925,1.6768478836617977,0.995760955144229,-0.2459980349044931,0.7014420888364408,0.3278265608377056,3.1483293001683137,3.882958953414374,-0.35799118461648044,0.15256614703595497,1.75109170...
2,812
Hormone metabolic process
8
28
2.905872
0.003662
Q9HB40,P42892,P16435,P30536,O95470,O75844,P05023,Q06124
Processes and pathways
GO Biological process
msigdb_gobp
217,171,108,14,113,57,184,189
1154,57,1438,113,184,1349,1350,693,1637,108,14,171,1411,471,189,221,629,512,614,481,882,1519,887,1989,217,857,1577,342
-0.026314622385095934,2.8772408406430023,-0.15377855875444413,1.970265053697904,1.3582082159271402,-0.11716687434726772,-0.11716687434726772,0.24063844353304098,-0.22747447582986668,2.0850480342379543,4.433024287479104,1.4656744516817248,-0.13545318694325917,0.49962950681326135,1.3427506872987998,1.1551542156307362,0.3...
2,812
Organic acid transmembrane transport
13
27
2.902185
0.003706
P23786,P33527,Q15041,P08183,P30825,Q9BQT8,Q02978,Q9H2D1,Q9H2H9,P31751,Q9Y619,O43772,Q9UBX3
Processes and pathways
GO Biological process
msigdb_gobp
128,411,195,71,386,77,271,48,239,373,119,89,59
89,861,1034,1081,71,924,2688,128,904,386,373,506,411,607,1819,520,271,195,611,834,77,48,239,760,59,430,119
2.2964854074361383,0.11708504290317308,0.027739919068620857,0.009759382165723819,2.665336704465738,0.08145780404230812,-1.062986143976836,1.780620541054555,0.09928977608158417,0.6179160419293773,0.6346847947097649,0.44844242471808454,0.5842822509907212,0.3278265608377056,-0.30181086948961583,0.4313132764939044,0.931196...
2,812
Oxidoreduction driven active transmembrane transporter activity
8
27
2.899997
0.003732
Q9UDW1,O96000,P03886,Q7KZN9,Q9P0J0,O43676,P13073,P47985
Functions
GO Molecular function
msigdb_gomf
64,225,100,133,170,10,146,147
1679,651,10,1276,477,1306,587,503,1307,902,225,590,100,723,1156,146,2084,673,1971,605,147,797,1982,133,170,64,231
-0.2459980349044931,0.2756186567217988,4.761828046714546,-0.0807106708667228,0.48260039141735633,-0.0989194316256046,0.34515985407120203,0.44844242471808454,-0.0989194316256046,0.09928977608158417,1.1393423790368928,0.34515985407120203,2.1984168906874886,0.22309537077734548,-0.026314622385095934,1.661926099494074,-0.43...
2,812
Regulation of lipid biosynthetic process
7
26
2.891244
0.003837
P49748,Q8WTV0,P16435,P30536,Q8NF37,Q13510,P05023
Processes and pathways
GO Biological process
msigdb_gobp
160,67,108,14,179,85,184
1154,636,1000,219,588,959,1111,184,1350,385,108,1922,14,1119,160,1166,85,2220,179,67,1221,379,2450,857,1477,1576
-0.026314622385095934,0.2930561203226198,0.04568305057423946,1.1551542156307362,0.34515985407120203,0.06358895367080376,-0.008258738440055532,1.3582082159271402,-0.11716687434726772,0.6179160419293773,2.0850480342379543,-0.35799118461648044,4.433024287479104,-0.008258738440055532,1.541660105153763,-0.026314622385095934...
2,812
Tetrapyrrole binding
8
14
2.889268
0.003861
O15173,P09601,Q7KZN9,Q16850,O00264,O43169,Q9H7Z7,P30519
Functions
GO Molecular function
msigdb_gomf
36,37,133,42,118,22,94,31
118,36,22,723,37,2728,31,42,133,155,1716,94,991,2701
1.8832252764522284,3.498161016050837,4.127427393456283,0.22309537077734548,3.4735930042919643,-1.2280559205447314,3.80008400175991,3.2495966741269706,1.7510917082093325,1.5869470337151412,-0.2459980349044931,2.2545833119587817,0.06358895367080376,-1.0834412629096282
2,812
Huntingtons disease
24
73
2.883155
0.003937
P12236,O43676,P45880,P13073,P47985,P42858,P21796,P14406,P21912,Q9Y277,Q13561,P24539,P63010,Q9UDW1,O14949,P14927,O15514,O96000,O75306,Q9Y6M9,P05141,Q00059,P22695,Q08752
Processes and pathways
KEGG Pathways
msigdb_kegg
261,10,17,146,147,275,23,28,410,164,291,435,437,64,70,344,223,225,477,231,487,377,250,509
1679,70,223,651,10,1276,477,1306,587,598,1686,503,1307,902,2648,225,590,1920,1399,487,843,723,672,926,844,1156,864,261,146,28,344,966,770,1538,2084,673,23,410,250,435,1968,2160,2210,1971,930,2252,605,532,275,17,147,972,2490,2092,1206,437,377,1551,509,1415,291,1058,1980,797,1982,757,2179,1382,64,2671,1267,164,231
-0.2459980349044931,2.665336704465738,1.1393423790368928,0.2756186567217988,4.761828046714546,-0.0807106708667228,0.48260039141735633,-0.0989194316256046,0.34515985407120203,0.3278265608377056,-0.2459980349044931,0.44844242471808454,-0.0989194316256046,0.09928977608158417,-0.9614575627830952,1.1393423790368928,0.345159...
2,812
Alcohol metabolic process
19
74
2.873962
0.004054
Q15800,Q10713,Q15392,O15269,Q9BQE5,P48449,P49748,P37268,Q16850,P48735,P04062,O15118,Q8WTV0,Q13510,Q14849,P51648,O76054,Q14739,P16435
Processes and pathways
GO Biological process
msigdb_gobp
129,138,150,151,26,154,160,38,42,173,55,56,67,85,221,91,219,235,108
2035,56,151,717,956,1151,1234,636,1000,219,588,1345,961,1636,2742,55,433,602,637,320,1402,1637,108,1041,1443,1541,2754,2778,38,1854,1362,154,173,160,1596,748,2435,91,519,822,457,2509,1650,555,2638,1603,138,1166,85,2791,1416,241,235,221,150,657,129,1168,42,512,755,614,882,67,2139,2230,26,2233,2027,2383,2708,857,1839,342
-0.41454454507068694,2.916446962695746,1.617013061048013,0.22309537077734548,0.06358895367080376,-0.026314622385095934,-0.06254040557376016,0.2930561203226198,0.04568305057423946,1.1551542156307362,0.34515985407120203,-0.11716687434726772,0.06358895367080376,-0.22747447582986668,-1.2908152269601356,2.9684696908889308,0...
2,812
Electron transport chain
13
62
2.871013
0.004092
Q9UDW1,O96000,P03886,Q7KZN9,O14949,O43819,Q9P0J0,O43676,P16435,Q9H3K2,P13073,P47985,P04062
Processes and pathways
GO Biological process
msigdb_gobp
64,225,100,133,70,200,170,10,108,207,146,147,55
1679,70,596,956,651,10,200,1151,1276,477,1306,587,861,503,1307,902,225,2535,590,100,55,1920,433,455,723,962,1156,637,146,965,2208,344,1637,966,108,2084,673,410,2249,1639,1971,2004,2252,1011,1362,147,1702,877,1327,2608,797,1982,1133,133,2139,2202,207,170,64,430,993,231
-0.2459980349044931,2.665336704465738,0.3278265608377056,0.06358895367080376,0.2756186567217988,4.761828046714546,1.2494429822888136,-0.026314622385095934,-0.0807106708667228,0.48260039141735633,-0.0989194316256046,0.34515985407120203,0.11708504290317308,0.44844242471808454,-0.0989194316256046,0.09928977608158417,1.139...
2,812
Cognitive impairment
45
151
2.860638
0.004228
P16278,Q9Y487,P07602,Q99720,Q10713,Q969G3,P17900,O75381,P42858,Q9Y2R0,P21964,Q03164,P54802,Q9BQE5,Q15437,O95831,P21912,P49327,Q8NHS3,Q6DKK2,O43681,P04062,O15118,Q5JTZ9,Q9NZ08,P36543,Q14108,Q9Y287,Q9Y263,Q92889,O43819,P01889,P54886,Q5XKP0,Q13510,O75503,Q9NQZ5,P40855,O60313,P50897,Q9NZJ7,O76024,P03886,O95470,Q9Y619
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
256,3,132,135,138,268,270,145,275,20,149,400,152,26,415,158,410,412,41,180,182,55,56,187,317,313,62,193,325,322,200,201,332,212,85,213,341,345,343,95,98,227,100,113,119
465,1342,56,182,200,343,2077,477,1344,145,213,227,623,113,158,768,590,201,100,55,842,1399,2124,2680,132,2332,2286,1112,2041,1780,1037,2688,864,256,2568,270,550,1042,1442,2538,1924,410,149,1405,1587,1969,2252,847,2778,744,313,1314,345,1119,2087,275,1786,1361,1642,412,1855,1089,95,748,2435,471,1857,152,332,932,655,2128,8...
0.49962950681326135,-0.11716687434726772,2.916446962695746,1.373639236931527,1.2494429822888136,0.7014420888364408,-0.4334795450313125,0.48260039141735633,-0.11716687434726772,1.661926099494074,1.1709381402052799,1.1235025176038205,0.31045870212056503,1.970265053697904,1.5567809266545096,0.18790247626968237,0.345159854...
2,812
Vacuole organization
10
44
2.860431
0.004231
Q8NHS3,Q8N511,P16615,O14773,O75503,P04062,P54802,Q96GC9,Q14108,P50897
Processes and pathways
GO Biological process
msigdb_gobp
41,12,144,148,213,55,152,122,62,95
2484,148,2656,213,623,739,55,2312,2332,214,741,144,2674,1119,1451,95,1856,1124,152,1241,1367,538,62,778,2396,2716,1292,1255,439,12,41,1464,2178,122,1988,2029,2141,836,1030,1183,668,1809,1811,1387
-0.7227042705874989,1.6469797626441487,-0.9816645976999411,1.1709381402052799,0.31045870212056503,0.2055167698607001,2.9684696908889308,-0.5672210487658126,-0.5865005631893707,1.1709381402052799,0.2055167698607001,1.6768478836617977,-1.0222261408317312,-0.008258738440055532,-0.15377855875444413,2.226542769012561,-0.320...
2,812
Receptor
8
24
2.850377
0.004367
Q8WTV0,Q9BUN8,Q567V2,Q9UQB8,O75381,A6NIH7,P15260,Q14108
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
67,136,8,44,145,21,185,62
21,1150,1635,145,1686,2648,1081,2635,185,2569,234,62,2014,8,1420,67,1799,136,987,1909,1994,1911,736,44
4.138917294144107,-0.026314622385095934,-0.22747447582986668,1.661926099494074,-0.2459980349044931,-0.9614575627830952,0.009759382165723819,-0.9211896151418975,1.3582082159271402,-0.801535746199426,1.0917382653656786,2.7453620538410717,-0.3956516265185736,4.900998556422755,-0.13545318694325917,2.678721796351966,-0.2831...
2,812
Abnormal circulating lipid concentration
29
66
2.849671
0.004376
P23786,Q15800,P07602,Q9H845,Q8N511,Q9NVI7,O75381,P42858,Q15392,P49748,Q9Y4P3,Q9UJS0,P37268,Q16836,O75844,Q9Y285,O75431,P40939,Q03252,O75880,O43772,P40855,Q9NZJ7,Q14739,O95470,P31751,P06737,P02545,P22830
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
128,129,132,265,12,273,145,275,150,160,298,430,38,438,57,318,65,331,458,208,89,345,98,235,113,373,372,371,126
2152,1846,89,145,65,597,57,208,113,371,2124,372,132,962,2794,126,128,1159,2042,373,2754,1784,793,38,345,331,275,816,697,160,533,748,471,1975,1820,655,2509,2338,1603,458,2341,2629,235,1288,150,657,129,1418,438,2057,12,1903,1618,1465,2418,1226,265,1227,273,98,857,2639,430,318,298,2387
-0.471476648351972,-0.3204965379073243,2.2964854074361383,1.661926099494074,2.6920877924017246,0.3278265608377056,2.8772408406430023,1.2024227010441528,1.970265053697904,0.6346847947097649,-0.45245684076640463,0.6346847947097649,1.7510917082093325,0.06358895367080376,-2.610253866866887,1.8247352597370783,1.780620541054...
2,812
Organelle subcompartment
103
313
2.846798
0.004416
Q7Z2K6,Q06136,O95772,Q8N511,P07099,O60725,O95197,Q9BQE5,P43307,P30519,Q86XL3,Q9NPR9,P09601,P37268,Q5BJF2,Q16850,Q9BRR6,Q96G23,Q8TCT9,Q9NQC3,P04062,O75844,Q9HD20,Q14108,Q9Y5M8,O00461,Q4ZIN3,P67812,Q8TB61,Q9P2W9,P51648,Q99943,Q9Y282,P16435,O95470,Q9NZ01,Q9BZF3,O00264,Q96GC9,A1L0T0,P35613,Q15629,O15260,Q15800,Q99720,Q9BUN...
Localization
GO Cellular component
msigdb_gocc
6,9,11,12,13,19,25,26,27,31,32,35,37,38,40,42,45,47,49,51,55,57,60,62,66,69,74,75,79,87,91,103,104,108,113,115,117,118,122,120,121,124,127,129,135,136,138,144,150,151,154,157,159,162,169,172,176,178,179,181,190,195,201,202,203,204,210,209,215,221,226,227,229,230,235,233,241,243,244,247,266,281,282,284,298,300,309,310,3...
120,2776,118,465,1677,69,2549,738,266,2687,901,635,1632,300,127,151,717,994,336,181,1635,2153,432,476,2406,19,1234,1683,999,1344,2656,636,1999,57,1034,227,2390,588,1488,1001,244,25,2000,113,923,959,466,11,740,1636,201,2742,55,204,504,1346,455,13,2363,1736,672,926,37,591,2635,928,108,144,639,1114,2569,2538,2409,1405,970...
1.8686378297720425,-1.7219202513137202,1.8832252764522284,0.49962950681326135,-0.2459980349044931,2.665336704465738,-0.7817584262207112,0.2055167698607001,0.9473814090258249,-1.062986143976836,0.09928977608158417,0.2930561203226198,-0.22747447582986668,0.8334597491992295,1.780620541054555,1.617013061048013,0.2230953707...
2,812
Cholesterol binding
7
14
2.844188
0.004452
O95772,P30536,P45880,Q9BZF3,P21796,O15118,Q14108
Functions
GO Molecular function
msigdb_gomf
11,14,17,117,23,56,62
56,636,588,11,1082,23,551,14,17,2509,62,221,349,117
2.916446962695746,0.2930561203226198,0.34515985407120203,4.707778885717138,0.009759382165723819,4.127427393456283,0.3969539001942955,4.433024287479104,4.287071828555498,-0.7423429355985278,2.7453620538410717,1.1551542156307362,0.7014420888364408,1.8977894929892263
2,812
Photophobia
12
36
2.831515
0.004633
Q9Y287,Q9NZJ7,P07602,Q92889,Q10567,P01889,Q13432,P51648,P04439,Q8WWV3,P48449,Q9NZ08
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
193,98,132,322,321,201,234,91,204,16,154,317
2484,2245,2246,1151,2154,1777,201,842,204,132,1965,769,550,1238,1042,1116,1088,331,154,412,1596,91,321,234,779,1254,1134,16,1516,1712,322,2464,317,98,193,526
-0.7227042705874989,-0.5287933290146903,-0.5287933290146903,-0.026314622385095934,-0.471476648351972,-0.283166031185393,1.2494429822888136,0.13484377635600422,1.218123559434321,1.7510917082093325,-0.3768005767007224,0.18790247626968237,0.3969539001942955,-0.06254040557376016,0.027739919068620857,-0.008258738440055532,0...
2,812
Establishment of protein localization to membrane
19
71
2.8282
0.004681
Q9NS69,Q15070,Q8NBU5,Q9Y512,O60725,O14737,Q9NPA0,P43307,Q96A33,O75608,Q9P0J0,O43681,O15118,Q9HD20,Q15041,P40855,P46379,P31751,Q15629
Processes and pathways
GO Biological process
msigdb_gobp
2,130,388,142,19,274,281,27,157,33,170,182,56,60,195,345,105,373,124
2189,2484,274,1632,56,182,577,19,33,1685,528,959,467,1155,2363,2592,1446,373,1358,1498,345,2161,27,105,1408,625,1856,2093,2613,2729,1017,1317,870,1125,1209,1602,1323,2574,749,195,778,130,124,1418,798,730,912,1870,1293,1946,388,157,1988,2028,2464,2753,2141,836,1105,60,281,2,170,516,1232,1477,2145,1480,1810,409,142
-0.490539185592664,-0.7227042705874989,0.9149813991987668,-0.22747447582986668,2.916446962695746,1.373639236931527,0.3624587383041505,4.207574767297518,3.75240658285758,-0.2459980349044931,0.4141504853427531,0.06358895367080376,0.49962950681326135,-0.026314622385095934,-0.6058241514720926,-0.8412307870350623,-0.1537785...
2,812
Protein insertion into membrane
9
22
2.827153
0.004696
Q9NS69,Q15070,P46379,Q9P0J0,Q9Y512,O14737,O43681,Q15629,Q96A33
Processes and pathways
GO Biological process
msigdb_gobp
2,130,105,170,142,274,182,124,157
274,182,577,528,1155,2592,1358,105,870,749,130,124,730,912,1870,1946,157,281,2,170,1810,142
0.9149813991987668,1.373639236931527,0.3624587383041505,0.4141504853427531,-0.026314622385095934,-0.8412307870350623,-0.11716687434726772,2.1277249347323828,0.11708504290317308,0.2055167698607001,1.7658680852573057,1.8540270682769622,0.22309537077734548,0.09928977608158417,-0.3204965379073243,-0.35799118461648044,1.571...
2,812
Macroautophagy
23
94
2.82588
0.004715
Q9Y487,O14681,Q9Y2S7,P16615,P42858,P21796,P51809,O15269,P09601,Q86VR2,Q9Y5X3,Q9UNH7,Q8NHS3,P61421,Q93050,Q96HY6,P04062,O15118,P36543,Q9Y5K8,Q9Y263,Q99623,Q96GC9
Processes and pathways
GO Biological process
msigdb_gobp
3,266,408,144,275,23,397,151,37,293,167,431,41,424,53,309,55,56,313,327,325,248,122
2150,266,584,56,151,717,475,1486,2656,1882,2390,623,739,565,55,1310,1399,487,1921,1736,37,864,144,1113,2674,694,674,23,313,1314,1119,275,1451,1856,397,1124,932,1241,424,1548,538,1209,1249,778,2396,683,2617,941,1292,1255,1613,293,439,41,2692,1464,1064,53,2178,2450,2021,122,1024,309,1988,2304,248,2560,944,595,2029,2141,8...
-0.471476648351972,0.9473814090258249,0.34515985407120203,2.916446962695746,1.617013061048013,0.22309537077734548,0.48260039141735633,-0.17214318056581754,-0.9816645976999411,-0.33922324092093464,-0.6251920440620977,0.31045870212056503,0.2055167698607001,0.37972336891623004,2.9684696908889308,-0.0989194316256046,-0.135...
2,812
Response to endoplasmic reticulum stress
19
73
2.823504
0.00475
O75955,Q7Z2K6,Q9BUN8,P16615,Q96A33,O95831,Q9Y4P3,Q8TCT9,Q96HY6,P27824,Q9H3N1,Q4ZIN3,P57088,Q9UBU6,P54578,P51572,Q9UM00,O76024,P46379
Processes and pathways
GO Biological process
msigdb_gobp
259,6,136,144,157,158,298,49,309,310,190,74,203,210,81,215,226,227,105
1814,1632,577,343,636,259,227,2390,588,1488,2000,158,903,1399,1400,529,1585,928,144,639,1586,2488,310,846,1407,105,215,81,932,906,203,2613,1548,1205,1125,1936,1894,2170,2440,936,2219,74,2174,731,1870,6,2702,1295,1762,49,1139,983,833,157,710,2450,887,309,1468,2139,583,136,987,190,1105,2386,210,226,1577,1808,2069,298,900
-0.30181086948961583,-0.22747447582986668,0.3624587383041505,0.7014420888364408,0.2930561203226198,0.9796636734407315,1.1235025176038205,-0.6251920440620977,0.34515985407120203,-0.17214318056581754,-0.3956516265185736,1.5567809266545096,0.09928977608158417,-0.13545318694325917,-0.13545318694325917,0.4141504853427531,-0...
2,812
Alcohol binding
7
17
2.820221
0.004799
O95772,P30536,P45880,Q9BZF3,P21796,O15118,Q14108
Functions
GO Molecular function
msigdb_gomf
11,14,17,117,23,56,62
2687,56,1234,636,588,11,1082,23,551,1494,14,17,2509,62,221,349,117
-1.062986143976836,2.916446962695746,-0.06254040557376016,0.2930561203226198,0.34515985407120203,4.707778885717138,0.009759382165723819,4.127427393456283,0.3969539001942955,-0.17214318056581754,4.433024287479104,4.287071828555498,-0.7423429355985278,2.7453620538410717,1.1551542156307362,0.7014420888364408,1.89778949298...
2,812
Biological oxidations
7
42
2.815932
0.004864
Q16850,P16435,P07099,Q8TB61,Q9H2H9,P21964,O43169
Processes and pathways
Reactome Pathways
msigdb_reactome
42,108,13,79,239,149,22
1529,635,22,1682,956,669,2504,1438,1345,1636,433,13,1083,2156,637,1402,108,1689,149,1443,929,2289,1541,1972,1363,773,414,1167,42,878,1375,79,1521,1763,1141,1716,239,254,2708,1145,1029,953
-0.1905472446215371,0.2930561203226198,4.127427393456283,-0.2459980349044931,0.06358895367080376,0.2581461514602102,-0.7423429355985278,-0.15377855875444413,-0.11716687434726772,-0.22747447582986668,0.5505191412386632,4.433024287479104,0.009759382165723819,-0.471476648351972,0.2930561203226198,-0.13545318694325917,2.08...
2,812
Endoplasmic reticulum
46
175
2.813739
0.004897
Q15800,Q9BUN8,O14681,P21964,O43169,O95197,O15269,P43307,Q8WUJ1,P84157,Q96A33,Q70UQ0,Q86XL3,Q96KA5,P37268,Q5BJF2,Q96A57,Q16850,P35790,Q9P035,Q96G23,Q8TCT9,Q9NQC3,Q8NF37,Q96HY6,P27824,Q9H3N1,Q15041,Q6UW68,Q4ZIN3,Q9BT22,Q9P2W9,P51572,Q14849,P51648,Q9UM00,O96005,Q96KC8,Q99943,Q14257,O95470,Q86UE4,Q9NZ01,O00264,Q96GC9,O1526...
Localization
Protein Atlas Subcellular
protein_atlas_subcellular_location_all
129,136,266,149,22,25,151,27,155,156,157,284,32,161,38,40,169,42,290,172,47,49,51,179,309,310,190,195,328,74,209,87,215,221,91,226,99,230,103,240,113,243,115,118,122,127
1728,118,738,266,1632,127,151,22,994,336,432,2551,1344,636,1034,2390,588,25,2000,113,466,99,1636,504,1346,1035,1081,529,862,2333,1585,1038,1039,928,1192,639,2364,1852,1539,2432,149,2315,968,2250,845,2488,310,653,1407,604,1280,2805,1010,290,2086,38,1886,745,27,1742,2412,1501,2088,2253,2489,1162,697,533,1645,2636,215,91,...
-0.2645618200989318,1.8832252764522284,0.2055167698607001,0.9473814090258249,-0.22747447582986668,1.780620541054555,1.617013061048013,4.127427393456283,0.04568305057423946,0.7180526668602384,0.5505191412386632,-0.7817584262207112,-0.11716687434726772,0.2930561203226198,0.027739919068620857,-0.6251920440620977,0.3451598...
2,812
Respiratory chain
9
28
2.810583
0.004945
Q9UDW1,O96000,P03886,O14949,Q9Y6M9,Q9P0J0,O43676,P47985,Q6DKK2
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
64,225,100,70,231,170,10,147,180
1679,70,651,10,1276,477,1306,587,503,1307,902,225,590,100,723,344,2084,250,1971,605,147,797,1982,180,461,170,64,231
-0.2459980349044931,2.665336704465738,0.2756186567217988,4.761828046714546,-0.0807106708667228,0.48260039141735633,-0.0989194316256046,0.34515985407120203,0.44844242471808454,-0.0989194316256046,0.09928977608158417,1.1393423790368928,0.34515985407120203,2.1984168906874886,0.22309537077734548,0.7014420888364408,-0.43347...
2,812
Mitochondrial envelope
106
263
2.810378
0.004948
P35232,P33121,Q99595,Q9NS69,O95168,Q70HW3,O60830,Q567V2,O43676,P30536,Q8WWV3,P45880,Q9Y2R0,O43169,P21796,P14406,Q8N4H5,Q9H061,O75964,P09601,Q96A26,Q6P4A7,Q9H2D1,Q8N2A8,Q9UBX3,Q9UDW1,O75431,O14949,Q9BQT8,Q13505,O43772,O95202,Q9NZJ7,P03886,Q8WY22,O00264,Q9Y619,P22830,P23786,Q15070,Q7KZN9,Q10713,Q9Y512,P13073,P47985,Q9Y6C...
Localization
GO Cellular component
msigdb_gocc
507,506,1,2,503,5,0,8,10,14,16,17,20,22,23,28,29,30,34,37,39,46,48,58,59,64,65,70,77,88,89,92,98,100,101,118,119,126,128,130,133,138,142,146,147,153,158,160,164,170,180,197,200,207,208,212,225,231,237,248,251,250,249,255,265,261,271,273,283,287,307,308,314,332,331,341,348,350,343,344,361,367,365,393,388,387,383,417,413...
118,465,1679,2330,2810,255,70,485,2626,22,383,651,10,89,200,343,2406,0,691,1276,477,1392,1306,65,2533,587,2407,1033,861,208,598,34,249,528,623,503,1307,92,902,959,466,158,225,768,1636,590,100,454,487,843,1884,723,1535,1737,37,844,1156,1401,2794,864,261,1851,146,28,344,966,1922,2158,639,1238,2084,673,23,410,1443,250,126...
1.8832252764522284,0.49962950681326135,-0.2459980349044931,-0.5865005631893707,-9.143898846056251,0.995760955144229,2.665336704465738,0.46553808003374114,-0.9011281689088609,4.127427393456283,0.6179160419293773,0.2756186567217988,4.761828046714546,2.2964854074361383,1.2494429822888136,0.7014420888364408,-0.644604473294...
2,812
Sphingolipid metabolism
12
22
2.805329
0.005027
P16278,Q9NZJ7,P07602,Q06136,Q96G23,O95470,Q13510,O43681,P04062,P10619,O15269,P51648
Processes and pathways
Reactome Pathways
msigdb_reactome
256,98,132,9,47,113,85,182,55,245,151,91
151,717,182,2000,113,55,2124,2680,132,2332,245,256,270,2409,91,9,85,47,2420,2527,98,2204
1.617013061048013,0.22309537077734548,1.373639236931527,-0.3956516265185736,1.970265053697904,2.9684696908889308,-0.45245684076640463,-1.0425811965372063,1.7510917082093325,-0.5865005631893707,1.0278684187598215,0.995760955144229,0.9311961834886229,-0.6446044732945461,2.2685717667150977,4.772602732969393,2.393526363136...
2,812
Lysosomal lumen
16
33
2.791124
0.005253
Q9UMR5,P16278,Q9NZJ7,P10619,P07602,P08236,Q8NHP8,P17900,O14773,Q13510,O43681,P04062,P54802,P10253,Q14108,P50897
Localization
GO Cellular component
msigdb_gocc
395,256,98,245,132,354,198,270,148,85,182,55,152,214,62,95
1678,2330,148,182,55,1584,2124,2680,132,2332,1349,1155,354,214,245,741,1850,2667,256,270,422,1120,95,152,2509,85,62,2643,1257,198,1334,98,395
-0.2459980349044931,-0.5865005631893707,1.6469797626441487,1.373639236931527,2.9684696908889308,-0.2089909446401189,-0.45245684076640463,-1.0425811965372063,1.7510917082093325,-0.5865005631893707,-0.11716687434726772,-0.026314622385095934,0.6848001484363205,1.1709381402052799,1.0278684187598215,0.2055167698607001,-0.32...
2,812
Alzheimers disease and mirna effects
22
73
2.787039
0.005319
P12236,P60900,P16615,P45880,P21796,O95197,P28074,Q9Y277,P49327,O00487,Q9NQC3,Q9UJX6,P28072,P49720,Q92542,Q02750,Q96IX5,P20618,P05141,Q96GC9,P31751,Q08752
Processes and pathways
WikiPathways
msigdb_wp
261,263,144,17,23,25,530,164,412,547,51,463,205,469,222,360,237,488,487,122,373,509
1272,547,1530,954,860,25,1310,487,1400,1921,1311,864,261,693,144,1922,724,1586,1195,488,23,743,1590,969,1115,641,1159,205,530,2085,1591,373,1046,1925,971,1119,815,17,1013,1643,412,469,553,2006,263,871,702,1205,2413,872,1209,360,1285,2722,1457,509,2011,1250,1287,1981,222,122,237,888,1298,2304,1989,1766,1470,51,463,897,1...
-0.0807106708667228,0.3969539001942955,-0.1905472446215371,0.06358895367080376,0.11708504290317308,4.092876418130871,-0.0989194316256046,0.46553808003374114,-0.13545318694325917,-0.35799118461648044,-0.0989194316256046,0.11708504290317308,0.9635371984080219,0.24063844353304098,1.6768478836617977,-0.35799118461648044,0....
2,812
Outer mitochondrial membrane protein complex
8
16
2.762017
0.005745
O75431,Q9NS69,Q9Y512,Q5XKP0,Q5HYI7,Q13505,Q8N4H5,Q6UXV4
Localization
GO Cellular component
msigdb_gocc
65,2,142,212,308,88,29,314
65,528,768,1315,88,348,849,308,212,314,1798,29,2,665,564,142
2.6920877924017246,0.4141504853427531,0.18790247626968237,-0.0989194316256046,2.3381987787788923,0.7014420888364408,0.13484377635600422,0.8170649925871301,1.186694264872841,0.7841840310190734,-0.283166031185393,3.882958953414374,5.214962353364934,0.2756186567217988,0.3969539001942955,1.721466835279003
2,812
Protein transmembrane transport
10
21
2.758709
0.005803
O60830,Q99595,Q9NS69,O75381,Q07820,Q15388,P31751,Q15629,O95831,O14925
Processes and pathways
GO Biological process
msigdb_gobp
0,1,2,145,251,348,373,124,158,255
255,383,0,145,528,158,768,1401,373,470,2613,1017,870,251,348,124,704,1,785,2,516
0.995760955144229,0.6179160419293773,5.214962353364934,1.661926099494074,0.4141504853427531,1.5567809266545096,0.18790247626968237,-0.13545318694325917,0.6346847947097649,0.49962950681326135,-0.8811147225178695,0.04568305057423946,0.11708504290317308,1.0118291637604662,0.7014420888364408,1.8540270682769622,0.2406384435...
2,812
Membrane lipid biosynthetic process
9
20
2.748026
0.005996
Q99805,Q8NBX0,Q06136,Q9P035,Q96G23,O95470,Q13510,P04062,O15269
Processes and pathways
GO Biological process
msigdb_gobp
323,134,9,172,47,113,85,55,151
151,717,336,1234,113,55,2409,9,1166,85,730,134,756,1465,47,617,323,2527,172,2204
1.617013061048013,0.22309537077734548,0.7180526668602384,-0.06254040557376016,1.970265053697904,2.9684696908889308,-0.6446044732945461,4.772602732969393,-0.026314622385095934,2.393526363136978,0.22309537077734548,1.7510917082093325,0.2055167698607001,-0.15377855875444413,3.1228430207611986,0.3278265608377056,0.76769756...
2,812
Corneal opacity
16
42
2.744949
0.006052
P16278,Q9Y4P3,Q92889,P08236,Q06136,P54886,O75381,Q9NVI7,P02545,Q13510,P04062,P10619,O75844,P51648,O95202,P40855
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
256,298,322,354,9,332,145,273,371,85,55,245,57,91,92,345
2152,2640,995,1881,2532,145,57,790,92,2123,371,55,1584,2124,354,1965,245,256,550,1042,2754,1784,345,818,91,492,332,2338,1603,9,1458,85,1288,1096,1707,387,322,273,857,2639,1030,298
-0.471476648351972,-0.9412993245634615,0.04568305057423946,-0.33922324092093464,-0.762027572092384,1.661926099494074,2.8772408406430023,0.17025232429825055,2.2545833119587817,-0.45245684076640463,0.6346847947097649,2.9684696908889308,-0.2089909446401189,-0.45245684076640463,0.6848001484363205,-0.3768005767007224,1.0278...
2,812
Cellular response to biotic stimulus
11
32
2.736282
0.006214
Q8IXJ6,Q8WTV0,Q9Y263,Q9UM00,O76024,P30536,P08670,Q86UE4,Q9NUQ9,O75844,Q96A33
Processes and pathways
GO Biological process
msigdb_gobp
131,67,325,226,227,14,238,243,312,57,157
788,57,227,1399,238,1351,385,638,1922,1406,2085,14,792,1827,540,850,2099,1254,2134,1563,243,131,2019,67,1800,157,2353,1384,312,2033,226,325
0.17025232429825055,2.8772408406430023,1.1235025176038205,-0.13545318694325917,1.0758136453276277,-0.11716687434726772,0.6179160419293773,0.2930561203226198,-0.35799118461648044,-0.13545318694325917,-0.4334795450313125,4.433024287479104,0.17025232429825055,-0.30181086948961583,0.4141504853427531,0.13484377635600422,-0....
2,812
Tetrapyrrole metabolic process
6
20
2.734778
0.006242
P09601,Q7KZN9,P30536,O00264,P22830,P30519
Processes and pathways
GO Biological process
msigdb_gobp
37,133,14,118,126,31
118,691,1112,37,126,1044,31,14,411,197,1122,472,2445,133,1716,855,802,2466,949,394
1.8832252764522284,0.24063844353304098,-0.008258738440055532,3.4735930042919643,1.8247352597370783,0.027739919068620857,3.80008400175991,4.433024287479104,0.5842822509907212,1.280653405466914,-0.008258738440055532,0.49962950681326135,-0.664061673412729,1.7510917082093325,-0.2459980349044931,0.13484377635600422,0.170252...
2,812
Lytic vacuole organization
8
20
2.728194
0.006368
Q8NHS3,Q8N511,O14773,O75503,P04062,P54802,Q14108,P50897
Processes and pathways
GO Biological process
msigdb_gobp
41,12,148,213,55,152,62,95
2484,148,213,739,55,2332,214,741,1119,95,1856,152,1367,62,2716,12,41,2178,1988,1809
-0.7227042705874989,1.6469797626441487,1.1709381402052799,0.2055167698607001,2.9684696908889308,-0.5865005631893707,1.1709381402052799,0.2055167698607001,-0.008258738440055532,2.226542769012561,-0.3204965379073243,1.617013061048013,-0.11716687434726772,2.7453620538410717,-1.1657691353785238,4.466400716267569,3.34979914...
2,812
Organic anion transmembrane transporter activity
18
28
2.72746
0.006382
P33527,Q14728,Q9UJS0,P12236,Q6NUK1,P30825,Q01650,Q9BQT8,Q02978,Q9H2D1,Q8TB61,O43808,Q9H2H9,P05141,Q9Y619,Q9HC21,Q9UBX3,Q15758
Functions
GO Molecular function
msigdb_gomf
411,163,430,261,387,386,520,77,271,48,79,586,239,487,119,350,59,611
1680,586,861,487,924,2688,864,261,386,411,607,1819,520,271,163,611,387,2054,79,834,77,48,239,760,350,59,430,119
-0.2459980349044931,0.34515985407120203,0.11708504290317308,0.46553808003374114,0.08145780404230812,-1.062986143976836,0.11708504290317308,0.9635371984080219,0.6179160419293773,0.5842822509907212,0.3278265608377056,-0.30181086948961583,0.4313132764939044,0.9311961834886229,1.5265139768993863,0.3278265608377056,0.617916...
2,812
Proton transporting two sector atpase complex
10
21
2.722018
0.006488
P56385,Q9Y487,O75964,P61421,Q8N511,Q96IX5,Q93050,P24539,P36543,Q9Y5K8
Localization
GO Cellular component
msigdb_gocc
413,3,34,424,12,237,53,435,313,327
598,34,843,694,674,435,2160,532,313,1314,972,447,413,424,1418,12,53,237,787,3,327
0.3278265608377056,3.55930743245453,0.13484377635600422,0.24063844353304098,0.2581461514602102,0.5505191412386632,-0.471476648351972,0.4141504853427531,0.7841840310190734,-0.0989194316256046,0.06358895367080376,0.5335887363165991,0.5842822509907212,0.5674169318211052,-0.13545318694325917,4.466400716267569,3.04597085429...
2,812
Porphyrin containing compound metabolic process
6
18
2.719287
0.006542
P09601,Q7KZN9,P30536,O00264,P22830,P30519
Processes and pathways
GO Biological process
msigdb_gobp
37,133,14,118,126,31
118,691,1112,37,126,1044,31,14,411,197,1122,472,2445,133,855,2466,949,394
1.8832252764522284,0.24063844353304098,-0.008258738440055532,3.4735930042919643,1.8247352597370783,0.027739919068620857,3.80008400175991,4.433024287479104,0.5842822509907212,1.280653405466914,-0.008258738440055532,0.49962950681326135,-0.664061673412729,1.7510917082093325,0.13484377635600422,-0.6835638805894443,0.081457...
2,812
Metallopeptidase activity
15
38
2.697124
0.006994
Q7L5N1,P36551,Q7Z2K6,P55786,Q9BYT8,O43847,Q10713,P42892,P09960,Q5JRX3,Q969V3,O75844,Q9NZ08,P52888,P22695
Functions
GO Molecular function
msigdb_gomf
260,197,6,102,428,232,138,171,139,177,380,57,317,283,250
1078,547,1109,232,2533,57,2389,2536,139,2727,693,250,2316,197,171,2006,283,102,138,177,1020,1254,260,6,833,380,1141,1764,443,1066,428,1805,1624,918,735,317,518,526
0.009759382165723819,0.3969539001942955,-0.008258738440055532,1.1076345177979037,-0.762027572092384,2.8772408406430023,-0.6251920440620977,-0.762027572092384,1.721466835279003,-1.2280559205447314,0.24063844353304098,1.0118291637604662,-0.5672210487658126,1.280653405466914,1.4656744516817248,-0.3956516265185736,0.882462...
2,812
Transition metal ion homeostasis
6
22
2.696215
0.007013
Q9Y487,P09601,O43819,Q8N511,Q8NEW0,P30519
Processes and pathways
GO Biological process
msigdb_gobp
3,37,200,12,125,31
2484,2284,200,2551,691,208,767,2536,1920,37,1043,31,867,1314,424,2294,1418,12,125,855,1069,3
-0.7227042705874989,-0.5479853796195989,1.2494429822888136,-0.7817584262207112,0.24063844353304098,1.2024227010441528,0.18790247626968237,-0.762027572092384,-0.35799118461648044,3.4735930042919643,0.027739919068620857,3.80008400175991,0.11708504290317308,-0.0989194316256046,0.5674169318211052,-0.5479853796195989,-0.135...
2,812
Abnormal macular morphology
6
24
2.693034
0.007081
Q8NHS3,P04439,Q13510,P04062,P51648,P50897
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
41,204,85,55,91,95
1234,55,2507,204,550,1238,1042,1116,2194,1925,1088,1596,95,91,1975,2437,85,878,1254,41,1516,1712,1669,226
-0.06254040557376016,2.9684696908889308,-0.7423429355985278,1.218123559434321,0.3969539001942955,-0.06254040557376016,0.027739919068620857,-0.008258738440055532,-0.490539185592664,-0.35799118461648044,0.009759382165723819,-0.2089909446401189,2.226542769012561,2.2685717667150977,-0.3768005767007224,-0.664061673412729,2....
2,812
Proton transmembrane transport
19
41
2.688888
0.007169
Q7KZN9,P13073,P47985,P36542,P56385,O75964,P61421,P24539,P05023,P36543,Q9UDW1,P56134,P00403,O75947,Q96ES6,P05141,P51790,Q13423,Q99623
Processes and pathways
GO Biological process
msigdb_gobp
133,146,147,532,413,34,424,435,184,313,64,447,590,598,112,487,242,510,248
1679,1680,1846,1276,598,34,590,184,487,843,723,1156,864,146,673,694,674,435,2160,1591,605,532,313,1314,147,972,242,447,413,424,975,510,133,2601,112,2139,248,64,1477,787,859
-0.2459980349044931,-0.2459980349044931,-0.3204965379073243,-0.0807106708667228,0.3278265608377056,3.55930743245453,0.34515985407120203,1.3582082159271402,0.46553808003374114,0.13484377635600422,0.22309537077734548,-0.026314622385095934,0.11708504290317308,1.661926099494074,0.2581461514602102,0.24063844353304098,0.2581...
2,812
Response to oxygen levels
12
56
2.684414
0.007266
Q9Y487,Q8IXJ6,Q9Y4P3,P09601,Q6RW13,Q96A26,P55786,Q8N511,Q15120,Q99623,O95831,P30519
Processes and pathways
GO Biological process
msigdb_gobp
3,131,298,37,229,39,102,12,83,248,158,31
1390,2549,1846,477,1999,1488,158,1489,371,2536,1920,1399,467,1534,529,37,2688,928,1922,2584,1042,1924,31,1006,1641,1314,1119,1854,412,2435,307,102,424,1700,1746,1166,83,1418,2660,1796,229,131,12,1464,2104,757,39,2450,887,248,1668,1384,1577,3,2069,298
-0.13545318694325917,-0.7817584262207112,-0.3204965379073243,0.48260039141735633,-0.3956516265185736,-0.17214318056581754,1.5567809266545096,-0.17214318056581754,0.6346847947097649,-0.762027572092384,-0.35799118461648044,-0.13545318694325917,0.49962950681326135,-0.1905472446215371,0.4141504853427531,3.4735930042919643,...
2,812
Mitochondrial protein containing complex
31
139
2.683007
0.007296
O60830,Q99595,Q9NS69,P12236,Q567V2,O43676,Q9Y512,P13073,P47985,P21796,P14406,Q8N4H5,O75964,Q9P0J0,Q5HYI7,Q6UXV4,Q9UDW1,O75431,O14949,P40939,Q5XKP0,Q15388,Q13505,O96000,P03886,Q9Y6M9,Q96IX5,Q99623,P22695,O76031,O14925
Localization
GO Cellular component
msigdb_gocc
0,1,2,261,8,10,142,146,147,23,28,29,34,170,308,314,64,65,70,331,212,348,88,225,100,231,237,248,250,249,255
1916,1679,255,70,651,10,1151,0,1276,477,1306,65,587,598,34,249,528,503,1307,902,225,768,590,100,487,843,1817,723,1535,962,844,1780,1156,1491,2583,864,261,146,28,344,966,2084,673,23,410,250,435,2160,1971,1591,2252,605,507,532,1315,331,147,972,2770,1596,1646,578,2008,1820,447,413,1601,874,2130,1550,1207,2595,1370,1324,88...
-0.35799118461648044,-0.2459980349044931,0.995760955144229,2.665336704465738,0.2756186567217988,4.761828046714546,-0.026314622385095934,5.214962353364934,-0.0807106708667228,0.48260039141735633,-0.0989194316256046,2.6920877924017246,0.34515985407120203,0.3278265608377056,3.55930743245453,1.0118291637604662,0.4141504853...
2,812
Cytochrome complex
7
17
2.679693
0.007369
Q9UDW1,Q7KZN9,O14949,P13073,P47985,P14406,P22695
Localization
GO Cellular component
msigdb_gocc
64,133,70,146,147,28,250
1679,70,590,723,844,1156,146,28,344,966,673,250,605,147,133,64,1810
-0.2459980349044931,2.665336704465738,0.34515985407120203,0.22309537077734548,0.13484377635600422,-0.026314622385095934,1.661926099494074,3.941725005389792,0.7014420888364408,0.06358895367080376,0.2581461514602102,1.0118291637604662,0.3278265608377056,1.661926099494074,1.7510917082093325,2.732071824115165,-0.2831660311...
2,812
Abnormality of hepatobiliary system physiology
19
64
2.674814
0.007477
P23786,Q10713,Q8N511,O75381,P55263,Q96A33,P04062,O15118,O43819,P01889,Q9BT22,Q5XKP0,Q13510,O43772,P03886,Q9Y619,Q96C23,P22695,P22830
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
128,138,12,145,18,157,55,56,200,201,209,212,85,89,100,119,252,250,126
2776,56,89,200,2531,477,145,597,2582,201,100,55,1347,600,723,962,2794,1404,250,126,128,904,2796,552,1886,345,331,1694,2087,472,1820,18,1977,2614,377,138,85,1653,426,1755,1168,438,212,913,1761,2057,12,1762,1565,157,252,2303,1223,209,265,1227,948,2183,1672,1810,1073,1482,2387,119
-1.7219202513137202,2.916446962695746,2.2964854074361383,1.2494429822888136,-0.762027572092384,0.48260039141735633,1.661926099494074,0.3278265608377056,-0.8213597823323313,1.2494429822888136,2.1984168906874886,2.9684696908889308,-0.11716687434726772,0.3278265608377056,0.22309537077734548,0.06358895367080376,-2.61025386...
2,812
transmembrane signal receptor
6
8
2.669062
0.007606
O15173,Q99720,Q9UMX5,O00264,Q96GC9,Q8WUJ1
Functions
Panther Protein class
panther_protein_class
36,135,141,118,122,155
118,36,1350,185,155,122,135,141
1.8832252764522284,3.498161016050837,-0.11716687434726772,1.3582082159271402,1.5869470337151412,1.8686378297720425,1.7510917082093325,1.721466835279003
2,812
Transporter
56
168
2.668779
0.007613
Q9Y487,P20020,Q15070,Q70HW3,P12236,Q6NUK1,P30825,Q8TEX9,P17900,Q02978,P16615,Q00765,Q9Y6C9,P51809,Q9BQE5,Q9Y3B3,P56385,P33527,Q9UJS0,Q8IXU6,P61421,Q8NFH4,Q9H2D1,Q86Y82,Q93050,O43493,P24539,Q9UBX3,P05023,P63010,Q9Y5K8,Q9Y3A6,Q99805,Q9HD45,P56134,P08183,Q10567,Q9BQT8,Q8TB61,P05026,Q9P2W9,P51572,Q15388,O43772,Q9HC21,O9520...
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
3,257,130,5,261,387,386,403,270,271,144,399,153,397,26,282,413,411,430,294,424,174,48,439,53,181,435,59,184,437,327,326,323,68,447,71,321,77,79,467,87,215,348,89,350,92,351,347,98,359,233,239,112,116,119,125
2769,1813,2484,1079,1729,1815,2284,718,181,116,89,586,501,1305,720,1683,691,1882,861,598,1001,92,2000,923,565,768,184,467,487,843,71,924,672,926,2688,566,864,261,144,270,257,694,674,435,2160,904,846,386,411,1010,532,1117,1314,1502,817,697,470,215,397,359,1744,607,2256,2336,2092,1819,1696,1201,1697,1366,1051,2127,447,41...
-1.6338631244210937,-0.30181086948961583,-0.7227042705874989,0.009759382165723819,-0.2645618200989318,-0.30181086948961583,-0.5479853796195989,0.22309537077734548,1.373639236931527,1.8977894929892263,2.2964854074361383,0.34515985407120203,0.44844242471808454,-0.0989194316256046,0.22309537077734548,-0.2459980349044931,0...
2,812
Alzheimers disease
21
52
2.656596
0.007893
O95168,O43676,P16615,P13073,P47985,P14406,P36542,P21912,P49327,P24539,Q9UDW1,O14949,P00403,O75489,Q92542,P14927,O96000,O75306,O75947,Q9Y6M9,P22695
Processes and pathways
KEGG Pathways
msigdb_kegg
503,10,144,146,147,28,532,410,412,435,64,70,590,587,222,344,225,477,598,231,250
1679,70,651,10,1276,477,1306,587,598,503,1307,902,225,590,1310,843,1921,723,844,1156,146,28,693,344,966,144,1922,2084,673,410,250,435,2160,1971,2085,2252,605,532,147,972,412,1209,2722,1457,1250,797,1982,222,1989,64,1477,231
-0.2459980349044931,2.665336704465738,0.2756186567217988,4.761828046714546,-0.0807106708667228,0.48260039141735633,-0.0989194316256046,0.34515985407120203,0.3278265608377056,0.44844242471808454,-0.0989194316256046,0.09928977608158417,1.1393423790368928,0.34515985407120203,-0.0989194316256046,0.13484377635600422,-0.3579...
2,812
Inner mitochondrial membrane organization
12
17
2.652758
0.007984
Q6UXV4,O75431,O94826,Q9Y4W6,Q9P0J0,Q9Y512,Q9H3K2,Q5XKP0,Q5HYI7,Q13505,O95202,O60313
Processes and pathways
GO Biological process
msigdb_gobp
314,65,528,526,170,142,207,212,308,88,92,343
343,65,528,92,1315,88,849,730,308,212,314,207,665,564,170,526,142
0.7014420888364408,2.6920877924017246,0.4141504853427531,2.2545833119587817,-0.0989194316256046,2.3381987787788923,0.13484377635600422,0.22309537077734548,0.8170649925871301,1.186694264872841,0.7841840310190734,1.218123559434321,0.2756186567217988,0.3969539001942955,1.4809227807404823,0.4313132764939044,1.7214668352790...
2,812
Delusions
7
17
2.652182
0.007997
Q9NZJ7,P07602,P36551,P21964,O43681,P04062,Q9BQE5
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
98,132,197,149,182,55,26
182,55,132,1112,149,197,275,1089,1122,1894,1605,2732,26,947,98,1478,430
1.373639236931527,2.9684696908889308,1.7510917082093325,-0.008258738440055532,1.6469797626441487,1.280653405466914,0.9149813991987668,0.009759382165723819,-0.008258738440055532,-0.33922324092093464,-0.2089909446401189,-1.2280559205447314,4.069774341527857,0.08145780404230812,2.226542769012561,-0.15377855875444413,0.567...
2,812
Inorganic anion transmembrane transporter activity
7
14
2.640718
0.008273
Q9Y277,P45880,P51790,O43681,P21796,Q9C0H2,Q9UBX3
Functions
GO Molecular function
msigdb_gomf
164,17,242,182,23,90,59
807,182,23,411,17,242,1051,271,522,2661,90,59,164,1340
0.15256614703595497,1.373639236931527,4.127427393456283,0.5842822509907212,4.287071828555498,1.043878838847843,0.027739919068620857,0.9311961834886229,0.4313132764939044,-0.9816645976999411,2.2964854074361383,2.8641358146662417,1.5265139768993863,-0.0989194316256046
2,812
Oxidoreductase activity acting on the ch ch group of donors
14
27
2.640375
0.008281
P49748,P21912,Q8N4Q0,Q7KZN9,Q9H845,P36551,Q14739,O15254,Q15067,Q8N8N7,Q9NZ01,Q15392,Q9H7Z7,Q709F0
Functions
GO Molecular function
msigdb_gomf
160,410,4,133,265,197,235,107,304,339,115,150,94,287
107,2794,410,2251,1044,2252,197,1161,412,160,1122,472,235,1417,304,150,287,133,4,339,943,855,2027,94,265,115,857
2.099295657499522,-2.610253866866887,0.5842822509907212,-0.5287933290146903,0.027739919068620857,-0.5287933290146903,1.280653405466914,-0.026314622385095934,0.5842822509907212,1.541660105153763,-0.008258738440055532,0.49962950681326135,1.0917382653656786,-0.13545318694325917,0.8334597491992295,1.6469797626441487,0.8661...
2,812
Sphingolipid biosynthetic process
6
14
2.637099
0.008362
Q06136,Q96G23,O95470,Q13510,P04062,O15269
Processes and pathways
GO Biological process
msigdb_gobp
9,47,113,85,55,151
151,717,113,55,2409,9,1166,85,730,47,323,2527,172,2204
1.617013061048013,0.22309537077734548,1.970265053697904,2.9684696908889308,-0.6446044732945461,4.772602732969393,-0.026314622385095934,2.393526363136978,0.22309537077734548,3.1228430207611986,0.7676975668159858,-0.7423429355985278,1.4504003260418334,-0.490539185592664
2,812
Neuron apoptotic process
9
42
2.633433
0.008453
O76024,P09601,Q96A26,Q99720,Q01105,P04062,Q92542,O95831,P50897
Processes and pathways
GO Biological process
msigdb_gobp
227,37,39,135,86,55,222,158,95
808,622,227,158,55,1920,1310,1399,1490,1083,37,1885,602,1924,373,1925,1361,676,1363,412,1855,95,2435,2007,1745,1090,1209,86,251,1864,1250,2511,909,222,1465,39,2139,135,2589,714,431,2069
0.15256614703595497,0.31045870212056503,1.1235025176038205,1.5567809266545096,2.9684696908889308,-0.35799118461648044,-0.0989194316256046,-0.13545318694325917,-0.17214318056581754,0.009759382165723819,3.4735930042919643,-0.33922324092093464,0.3278265608377056,-0.35799118461648044,0.6346847947097649,-0.35799118461648044...
2,812
Oxidase
11
19
2.627463
0.008602
P49748,Q15800,P36551,Q9H845,O43819,O15254,O75880,O43169,P14406,Q709F0,O15260
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
160,129,197,265,200,107,208,22,28,287,127
107,127,22,200,208,1156,2794,965,28,966,673,2251,197,160,304,129,594,287,265
2.099295657499522,1.780620541054555,4.127427393456283,1.2494429822888136,1.2024227010441528,-0.026314622385095934,-2.610253866866887,0.06358895367080376,3.941725005389792,0.06358895367080376,0.2581461514602102,-0.5287933290146903,1.280653405466914,1.541660105153763,0.8334597491992295,1.780620541054555,0.345159854071202...
2,812
Oxidoreductase complex
16
53
2.627375
0.008605
Q9UDW1,O96000,P21912,O95168,O75306,O14949,P03886,Q9Y6M9,O43676,Q9P0J0,Q96CU9,P47985,O43169,P31350,P22695,P14927
Localization
GO Cellular component
msigdb_gocc
64,225,410,503,477,70,100,231,10,170,461,147,22,436,250,344
1679,70,22,651,10,1151,1276,477,1306,587,503,1307,902,225,1533,1636,100,1884,529,1817,723,962,1780,1491,2583,1038,965,344,2084,410,250,1639,1588,1971,2252,436,605,2612,1011,1362,147,1596,1321,797,1982,1375,1098,461,170,64,1810,993,231
-0.2459980349044931,2.665336704465738,4.127427393456283,0.2756186567217988,4.761828046714546,-0.026314622385095934,-0.0807106708667228,0.48260039141735633,-0.0989194316256046,0.34515985407120203,0.44844242471808454,-0.0989194316256046,0.09928977608158417,1.1393423790368928,-0.1905472446215371,-0.22747447582986668,2.198...
2,812
Protein transporter activity
10
14
2.621946
0.008743
O60830,Q99595,Q9NS69,Q9UGP8,Q8NBU5,Q9HD20,P49755,Q15388,Q07820,O14925
Functions
GO Molecular function
msigdb_gomf
0,1,2,516,388,60,470,348,251,255
255,0,528,768,1350,470,870,251,348,388,1,60,2,516
0.995760955144229,5.214962353364934,0.4141504853427531,0.18790247626968237,-0.11716687434726772,0.49962950681326135,0.11708504290317308,1.0118291637604662,0.7014420888364408,0.6179160419293773,5.214962353364934,2.8378709383397114,5.214962353364934,0.44844242471808454
2,812
Nadh dehydrogenase complex assembly
11
22
2.619661
0.008802
O96000,Q15070,O75306,P03886,Q9H845,Q9Y6M9,O43676,Q9P0J0,Q96CU9,Q8N183,Q9H061
Processes and pathways
GO Biological process
msigdb_gobp
225,130,477,100,265,231,10,170,461,417,30
651,10,1276,477,587,503,902,225,100,1971,130,797,1982,417,461,30,265,1525,170,1810,993,231
0.2756186567217988,4.761828046714546,-0.0807106708667228,0.48260039141735633,0.34515985407120203,0.44844242471808454,0.09928977608158417,1.1393423790368928,2.1984168906874886,-0.3768005767007224,1.7658680852573057,0.17025232429825055,-0.3768005767007224,0.5842822509907212,0.5166255731433357,3.8356886250962248,0.9635371...
2,812
transporter
9
56
2.617852
0.008849
O60830,Q99595,Q15070,Q9HD45,Q567V2,Q8NFH4,Q9H2D1,Q9Y619,O43772
Functions
Panther Protein class
panther_protein_class
0,1,130,68,8,174,48,119,89
1435,1729,1815,2284,1150,301,383,182,89,1305,0,2247,589,2554,1117,817,2470,359,1744,2491,607,1819,1201,905,2127,655,870,520,796,1095,130,8,2661,799,732,174,733,403,2104,800,1567,616,1264,1,323,2519,759,48,1909,68,1911,2706,2602,859,2387,119
-0.15377855875444413,-0.2645618200989318,-0.30181086948961583,-0.5479853796195989,-0.026314622385095934,0.8334597491992295,0.6179160419293773,1.373639236931527,2.2964854074361383,-0.0989194316256046,5.214962353364934,-0.5287933290146903,0.34515985407120203,-0.7817584262207112,-0.008258738440055532,0.15256614703595497,-...
2,812
Alcohol biosynthetic process
10
33
2.617714
0.008852
Q15800,P37268,Q16850,P16435,Q13510,Q15392,P04062,O15269,P48449,O76054
Processes and pathways
GO Biological process
msigdb_gobp
129,38,42,108,85,150,55,151,154,219
2035,151,717,636,219,588,961,1636,2742,55,602,320,108,1041,2778,38,1854,154,519,457,2638,1166,85,1416,235,150,657,129,1168,42,2139,2383,857
-0.41454454507068694,1.617013061048013,0.22309537077734548,0.2930561203226198,1.1551542156307362,0.34515985407120203,0.06358895367080376,-0.22747447582986668,-1.2908152269601356,2.9684696908889308,0.3278265608377056,0.7676975668159858,2.0850480342379543,0.027739919068620857,-1.8333497016212914,3.4735930042919643,-0.320...
2,812
Cutaneous photosensitivity
8
19
2.616075
0.008895
Q92889,P36551,P37268,P14324,Q06136,O76031,P22830,Q14108
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
322,197,38,320,9,249,126,62
249,842,769,2727,320,550,1042,126,1739,1116,197,38,1122,9,363,62,322,857,1528
1.0118291637604662,0.13484377635600422,0.18790247626968237,-1.2280559205447314,0.7676975668159858,0.3969539001942955,0.027739919068620857,1.8247352597370783,-0.2645618200989318,-0.008258738440055532,1.280653405466914,3.4735930042919643,-0.008258738440055532,4.772602732969393,0.6514216381177684,2.7453620538410717,0.7676...
2,812
Molecular transducer activity
9
31
2.61604
0.008896
Q8WTV0,O15173,Q99720,Q9BUN8,P30536,O15118,P15260,Q15629,Q14108
Functions
GO Molecular function
msigdb_gomf
67,36,135,136,14,56,185,124,62
56,36,808,1081,1350,1084,2635,185,2569,14,2788,412,1055,2722,1130,825,62,124,611,570,612,1420,229,67,1518,1952,135,136,2526,2308,516
2.916446962695746,3.498161016050837,0.15256614703595497,0.009759382165723819,-0.11716687434726772,0.009759382165723819,-0.9211896151418975,1.3582082159271402,-0.801535746199426,4.433024287479104,-2.1771642860934013,0.5842822509907212,0.027739919068620857,-1.1864793952065424,-0.008258738440055532,0.15256614703595497,2.7...
2,812
Atpase coupled transmembrane transporter activity
10
18
2.614306
0.008941
P33527,P20020,P08183,P61421,Q9HD20,P16615,P36543,Q15388,P05023,Q9Y5K8
Functions
GO Molecular function
msigdb_gomf
411,257,71,424,60,144,313,348,184,327
691,184,467,843,71,144,257,694,674,904,411,313,1314,424,348,60,787,327
0.24063844353304098,1.3582082159271402,0.49962950681326135,0.13484377635600422,2.665336704465738,1.6768478836617977,0.995760955144229,0.24063844353304098,0.2581461514602102,0.09928977608158417,0.5842822509907212,0.7841840310190734,-0.0989194316256046,0.5674169318211052,0.7014420888364408,2.8378709383397114,0.1879024762...
2,812
Monovalent inorganic cation homeostasis
7
26
2.603924
0.009216
Q9Y487,Q9Y5X3,Q8N511,Q93050,O75503,P05023,P50897
Processes and pathways
GO Biological process
msigdb_gobp
3,167,12,53,213,184,95
213,739,1236,184,467,843,2085,95,1856,242,1697,1051,424,777,1418,12,2104,2601,53,2178,2737,1477,787,3,167,1340
1.1709381402052799,0.2055167698607001,-0.06254040557376016,1.3582082159271402,0.49962950681326135,0.13484377635600422,-0.4334795450313125,2.226542769012561,-0.3204965379073243,1.043878838847843,-0.2459980349044931,0.027739919068620857,0.5674169318211052,0.18790247626968237,-0.13545318694325917,4.466400716267569,-0.4334...
2,812
Sphingolipid metabolism
7
9
2.594291
0.009479
P07602,Q06136,O95470,Q9NZ01,Q13510,P04062,O15269
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
132,9,113,115,85,55,151
151,717,113,55,132,270,9,85,115
1.617013061048013,0.22309537077734548,1.970265053697904,2.9684696908889308,1.7510917082093325,0.9311961834886229,4.772602732969393,2.393526363136978,1.970265053697904
2,812
Abnormality of the mitochondrion
23
79
2.590966
0.009571
P23786,Q70HW3,Q7KZN9,Q9H845,O43676,Q9BQP7,P13073,Q9Y2R0,Q8N183,P49748,P21912,Q9P0J0,Q5JPH6,Q16836,Q9UBX3,Q96CU9,P40939,O00429,O75880,O43772,O96000,P03886,Q9Y6M9
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
128,5,133,265,10,272,146,20,417,160,410,170,305,438,59,461,331,465,208,89,225,100,231
465,1679,10,89,1276,477,1306,587,597,208,902,225,590,100,1817,962,1780,1491,2794,864,146,965,2084,673,410,1443,128,1969,1971,531,2252,744,1011,331,2087,1642,1120,160,578,2008,1976,932,2165,975,876,1249,1374,2608,1982,438,704,798,305,2445,2053,5,133,1462,417,1565,2302,461,1664,1223,2610,1989,272,2028,265,1525,170,949,59...
0.49962950681326135,-0.2459980349044931,4.761828046714546,2.2964854074361383,-0.0807106708667228,0.48260039141735633,-0.0989194316256046,0.34515985407120203,0.3278265608377056,1.2024227010441528,0.09928977608158417,1.1393423790368928,0.34515985407120203,2.1984168906874886,-0.30181086948961583,0.06358895367080376,-0.283...
2,812
Schizophrenia
7
18
2.590691
0.009578
Q9NZJ7,P07602,P16615,P21964,O43681,P04062,Q9BQE5
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
98,132,144,149,182,55,26
182,2077,227,55,132,144,149,1696,1936,1901,2020,983,1988,26,835,2561,2110,98
1.373639236931527,-0.4334795450313125,1.1235025176038205,2.9684696908889308,1.7510917082093325,1.6768478836617977,1.6469797626441487,-0.2459980349044931,-0.35799118461648044,-0.33922324092093464,-0.3956516265185736,0.06358895367080376,-0.3768005767007224,4.069774341527857,0.15256614703595497,-0.7817584262207112,-0.4334...
2,812
Cytochrome complex assembly
6
8
2.583162
0.00979
Q15070,Q7KZN9,O43819,P47985,Q6DKK2,Q9Y2R0
Processes and pathways
GO Biological process
msigdb_gobp
130,133,200,147,180,20
200,208,147,130,180,133,1810,20
1.2494429822888136,1.2024227010441528,1.661926099494074,1.7658680852573057,1.389043853750546,1.7510917082093325,-0.283166031185393,4.150393709731816
2,812
Alzheimers disease
20
71
2.571071
0.010138
P12236,P60900,P16615,P45880,P21796,O95197,P28074,Q9Y277,P49327,O00487,Q9NQC3,Q9UJX6,P28072,P49720,Q92542,Q02750,P20618,P05141,P31751,Q08752
Processes and pathways
WikiPathways
msigdb_wp
261,263,144,17,23,25,530,164,412,547,51,463,205,469,222,360,488,487,373,509
1272,547,1530,954,860,25,1310,487,1400,1921,1311,864,261,693,144,1922,724,1586,1195,488,23,743,1590,969,1115,641,1159,205,530,2085,1591,373,1046,1925,971,1119,815,17,1013,1643,412,469,553,2006,263,871,702,1205,2413,872,1209,360,1285,2722,1457,509,2011,1250,1287,1981,222,888,1298,2304,1989,1766,1470,51,463,897,164
-0.0807106708667228,0.3969539001942955,-0.1905472446215371,0.06358895367080376,0.11708504290317308,4.092876418130871,-0.0989194316256046,0.46553808003374114,-0.13545318694325917,-0.35799118461648044,-0.0989194316256046,0.11708504290317308,0.9635371984080219,0.24063844353304098,1.6768478836617977,-0.35799118461648044,0....
2,812
acyltransferase
8
15
2.560821
0.010443
P23786,P14324,Q99943,Q9BWD1,Q8NCC3,Q92696,Q8NF37,P49356
Functions
Panther Protein class
panther_protein_class
128,320,103,76,43,114,179,93
485,320,128,1589,1854,746,93,1820,571,43,179,379,114,103,76
0.46553808003374114,0.7676975668159858,1.780620541054555,-0.2089909446401189,-0.3204965379073243,0.2055167698607001,2.2545833119587817,-0.30181086948961583,0.37972336891623004,3.1864309983263617,1.4044221691939036,0.6346847947097649,1.970265053697904,2.1560667669732525,2.557560972127124
2,812
Neuron death
12
62
2.554979
0.010619
O76024,P09601,Q99720,Q96A26,Q4ZIN3,Q9UMX5,Q15392,P04062,Q01105,Q92542,O95831,P50897
Processes and pathways
GO Biological process
msigdb_gobp
227,37,135,39,74,141,150,55,86,222,158,95
808,622,1034,227,158,55,1920,1310,1399,1400,1490,1083,1536,37,1885,602,1922,1924,373,1925,1361,676,1363,412,1855,95,2435,2007,1745,1090,871,437,1125,1209,86,1936,251,2196,1864,2294,1250,2511,909,150,74,222,1465,39,2450,1988,2139,135,2589,836,1384,714,1477,1957,141,431,2590,2069
0.15256614703595497,0.31045870212056503,0.027739919068620857,1.1235025176038205,1.5567809266545096,2.9684696908889308,-0.35799118461648044,-0.0989194316256046,-0.13545318694325917,-0.13545318694325917,-0.17214318056581754,0.009759382165723819,-0.1905472446215371,3.4735930042919643,-0.33922324092093464,0.327826560837705...
2,812
Cation transport
46
140
2.554958
0.01062
P20020,Q70HW3,Q7KZN9,Q9Y4W6,P30825,Q4KMQ2,Q01650,P30536,P16615,P13073,P47985,P42858,P21796,P51809,P78417,P56385,O75964,O15173,Q9UNH7,P61421,O14936,P24539,O75844,Q9HD20,P05023,P36543,Q9UDW1,P56134,O00429,P05026,Q9HC21,O43772,Q99623,O95202,O43865,Q9UM00,O76024,Q9H2H9,Q96ES6,P05141,P51790,Q13423,Q9Y619,Q96GC9,Q13555,Q8NEW...
Processes and pathways
GO Biological process
msigdb_gobp
257,5,133,526,386,522,520,14,144,146,147,275,23,397,414,413,34,36,431,424,299,435,57,60,184,313,64,447,465,467,350,89,248,92,476,226,227,239,112,487,242,510,119,122,511,125
2769,465,1679,1680,299,36,1846,89,586,476,997,691,1276,1392,1486,2533,57,598,34,227,92,590,2536,1236,184,467,487,1081,1440,843,2312,1921,1082,924,723,1156,863,602,864,146,964,144,1113,2158,2751,257,1239,673,694,674,2538,23,435,1086,2160,2210,2289,1591,14,867,386,605,1046,1925,1927,532,313,1314,275,1408,2254,147,972,154...
-1.6338631244210937,0.49962950681326135,-0.2459980349044931,-0.2459980349044931,0.8334597491992295,3.498161016050837,-0.3204965379073243,2.2964854074361383,0.34515985407120203,0.48260039141735633,0.04568305057423946,0.24063844353304098,-0.0807106708667228,-0.13545318694325917,-0.17214318056581754,-0.762027572092384,2.8...
2,812
Biliary tract abnormality
9
25
2.548957
0.010805
Q9NZJ7,P07602,P09601,Q10713,Q5XKP0,O43681,P04062,O95202,Q14108
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
98,132,37,138,212,182,55,92,62
182,92,2123,371,55,132,37,638,1689,1641,471,138,1458,62,235,212,322,1619,2303,2464,948,98,2671,1810,2387
1.373639236931527,2.2545833119587817,-0.45245684076640463,0.6346847947097649,2.9684696908889308,1.7510917082093325,3.4735930042919643,0.2930561203226198,-0.2459980349044931,-0.22747447582986668,0.49962950681326135,1.7362913212685769,-0.15377855875444413,2.7453620538410717,1.0917382653656786,1.186694264872841,0.76769756...
2,812
Oxidoreductase activity acting on the ch ch group of donors nad or nadp as acceptor
7
14
2.543965
0.01096
P49327,Q8N4Q0,Q14739,Q9NZ01,Q8N8N7,Q15392,Q9H7Z7
Functions
GO Molecular function
msigdb_gomf
412,4,235,115,339,150,94
1044,1161,412,472,235,1417,150,4,339,855,2027,94,115,857
0.027739919068620857,-0.026314622385095934,0.5842822509907212,0.49962950681326135,1.0917382653656786,-0.13545318694325917,1.6469797626441487,5.194333871316421,0.7180526668602384,0.13484377635600422,-0.3956516265185736,2.2545833119587817,1.970265053697904,0.13484377635600422
2,812
Cellular homeostasis
27
129
2.54276
0.010998
Q9Y487,P20020,Q8N511,P16615,P42858,Q96A33,P09601,Q9NQC3,P52789,Q93050,P05023,Q9HD20,Q9Y263,O43819,Q8N5M9,Q15120,O75880,O75503,P10253,P51572,O95202,P50897,Q9UM00,O76024,P51790,Q07820,Q8NEW0
Processes and pathways
GO Biological process
msigdb_gobp
3,257,12,144,275,157,37,51,307,53,184,60,325,200,334,83,208,213,214,215,92,95,226,227,242,251,125
1813,2484,2284,1680,200,997,2551,691,213,208,767,227,92,2000,739,2535,2536,1188,184,467,1440,843,2332,1350,1082,862,1351,37,962,214,1004,964,928,693,144,2568,1113,2751,1238,257,1043,2409,2210,2488,2289,2085,2005,1198,1495,867,792,1314,275,1363,95,1856,1889,215,242,700,307,1201,2652,1697,1051,2637,1018,424,537,727,1053,...
-0.30181086948961583,-0.7227042705874989,-0.5479853796195989,-0.2459980349044931,1.2494429822888136,0.04568305057423946,-0.7817584262207112,0.24063844353304098,1.1709381402052799,1.2024227010441528,0.18790247626968237,1.1235025176038205,2.2545833119587817,-0.3956516265185736,0.2055167698607001,-0.762027572092384,-0.762...
2,812
Intracellular protein transmembrane transport
8
18
2.537395
0.011168
O60830,Q99595,O75381,Q15388,P31751,Q15629,O95831,O14925
Processes and pathways
GO Biological process
msigdb_gobp
0,1,145,348,373,124,158,255
255,383,0,145,528,158,768,1401,373,2613,1017,870,348,124,704,1,785,516
0.995760955144229,0.6179160419293773,5.214962353364934,1.661926099494074,0.4141504853427531,1.5567809266545096,0.18790247626968237,-0.13545318694325917,0.6346847947097649,-0.8811147225178695,0.04568305057423946,0.11708504290317308,0.7014420888364408,1.8540270682769622,0.24063844353304098,5.214962353364934,0.18790247626...
2,812
Passive transmembrane transporter activity
12
28
2.534211
0.01127
P56385,P24539,O75964,Q9Y277,P56134,Q9UM00,Q4KMQ2,P45880,Q99797,P51790,P21796,Q9C0H2
Functions
GO Molecular function
msigdb_gomf
413,435,34,164,447,226,522,17,443,242,23,90
807,598,34,768,843,2312,1082,23,435,2160,532,1314,17,972,242,2652,447,413,870,1209,522,1518,443,2324,90,226,164,1340
0.15256614703595497,0.3278265608377056,3.55930743245453,0.18790247626968237,0.13484377635600422,-0.5672210487658126,0.009759382165723819,4.127427393456283,0.5505191412386632,-0.471476648351972,0.4141504853427531,-0.0989194316256046,4.287071828555498,0.06358895367080376,1.043878838847843,-0.9614575627830952,0.5335887363...
2,812
Organic acid transmembrane transporter activity
9
20
2.5337
0.011287
P33527,P08183,P30825,Q9BQT8,Q02978,Q9H2D1,Q9H2H9,Q9Y619,Q9UBX3
Functions
GO Molecular function
msigdb_gomf
411,71,386,77,271,48,239,119,59
1680,861,71,924,386,411,607,1819,520,271,611,2054,834,77,48,239,760,59,430,119
-0.2459980349044931,0.11708504290317308,2.665336704465738,0.08145780404230812,0.6179160419293773,0.5842822509907212,0.3278265608377056,-0.30181086948961583,0.4313132764939044,0.9311961834886229,0.3278265608377056,-0.41454454507068694,0.15256614703595497,2.5440011741485096,3.110074180270112,1.0758136453276277,0.20551676...
2,812
Sterol binding
7
17
2.513286
0.011961
O95772,P30536,P45880,Q9BZF3,P21796,O15118,Q14108
Functions
GO Molecular function
msigdb_gomf
11,14,17,117,23,56,62
56,636,588,11,1082,23,2409,551,14,17,2509,62,221,357,2786,349,117
2.916446962695746,0.2930561203226198,0.34515985407120203,4.707778885717138,0.009759382165723819,4.127427393456283,-0.6446044732945461,0.3969539001942955,4.433024287479104,4.287071828555498,-0.7423429355985278,2.7453620538410717,1.1551542156307362,0.6848001484363205,-2.1537802662741563,0.7014420888364408,1.8977894929892...
2,812
Polyneuropathy
8
17
2.510164
0.012068
Q9NZJ7,Q15041,P07602,P03886,Q15120,Q8N2K0,Q9HC21,O95831
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
98,195,132,100,83,247,350,158
343,565,158,100,1584,132,724,1924,605,1602,195,83,1760,247,350,98,666
0.7014420888364408,0.37972336891623004,1.5567809266545096,2.1984168906874886,-0.2089909446401189,1.7510917082093325,0.22309537077734548,-0.35799118461648044,0.3278265608377056,-0.2089909446401189,1.3117556902397782,2.448526345052684,-0.2645618200989318,1.0278684187598215,0.7014420888364408,2.226542769012561,0.275618656...
2,812
Endoplasmic reticulum
122
407
2.504177
0.012274
Q7Z2K6,Q06136,O95772,Q8N511,P30536,P07099,O60725,O95197,Q9BQE5,P43307,P30519,Q86XL3,O75608,O15173,P09601,P37268,Q5BJF2,Q16850,Q9UQB8,Q9BRR6,Q96G23,Q8TCT9,Q9NQC3,P04062,O15118,O75844,Q9HD20,Q14108,Q9Y5M8,Q4ZIN3,P67812,P80303,Q8TB61,Q13510,Q01105,Q9P2W9,P51648,Q99943,Q9Y282,P16435,P55327,O95470,Q9NZ01,Q9BZF3,O00264,Q96GC...
Localization
GO Cellular component
msigdb_gocc
6,9,11,12,14,13,19,25,26,27,31,32,33,36,37,38,40,42,44,45,47,49,51,55,56,57,60,62,66,74,75,78,79,85,86,87,91,103,104,108,111,113,115,117,118,122,120,121,124,127,129,135,136,141,144,150,151,154,156,157,159,162,169,172,176,178,179,181,182,184,190,195,201,202,203,204,210,209,213,215,221,222,226,227,229,230,235,233,240,241...
120,2776,118,465,2549,2330,738,266,2687,635,1632,56,36,353,127,151,717,2633,994,336,1437,181,182,432,476,2406,996,19,1234,1683,999,1344,2656,636,213,33,789,57,1034,227,1685,2627,2390,588,1488,1001,244,25,2000,599,922,113,923,959,466,11,2001,903,740,1687,1636,201,2742,55,204,1399,504,1346,184,1035,455,13,529,2363,1736,3...
1.8686378297720425,-1.7219202513137202,1.8832252764522284,0.49962950681326135,-0.7817584262207112,-0.5865005631893707,0.2055167698607001,0.9473814090258249,-1.062986143976836,0.2930561203226198,-0.22747447582986668,2.916446962695746,3.498161016050837,0.6848001484363205,1.780620541054555,1.617013061048013,0.223095370777...
2,812
Elevated hepatic transaminase
25
84
2.50003
0.012418
P23786,Q9H845,Q10713,Q8N511,P55263,P49748,Q14746,Q9UJS0,Q15067,Q9Y285,O75431,Q92889,P01889,P40939,O75880,Q5XKP0,Q13510,P10253,O43772,P40855,Q14739,Q9Y619,Q00059,P06737,P22695
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
128,265,138,12,18,160,426,430,304,318,65,322,201,331,208,212,85,214,89,345,235,119,377,372,250
2776,89,1234,65,597,486,208,1533,201,1399,372,723,1535,962,214,2794,864,2727,1404,673,250,929,128,1159,904,2042,793,1592,1785,1886,345,331,1694,160,1122,471,2008,1820,18,2437,1977,1017,874,2614,377,1602,1603,2573,1371,138,85,235,426,304,1418,729,438,1289,939,212,1761,754,2662,1462,12,1220,322,2418,2610,1104,595,265,122...
-1.7219202513137202,2.2964854074361383,-0.06254040557376016,2.6920877924017246,0.3278265608377056,0.46553808003374114,1.2024227010441528,-0.1905472446215371,1.2494429822888136,-0.13545318694325917,0.6346847947097649,0.22309537077734548,-0.1905472446215371,0.06358895367080376,1.1709381402052799,-2.610253866866887,0.1170...
2,812
Process utilizing autophagic mechanism
36
137
2.497149
0.01252
Q9Y487,Q8IXJ6,Q9UII2,P07602,O14681,P30536,Q9Y2S7,P16615,P42858,P21796,P51809,O15269,P09601,Q86VR2,Q9Y5X3,Q9UNH7,Q8NHS3,P61421,P04792,P52789,Q93050,Q96HY6,P04062,O15118,O75844,P36543,Q9Y5K8,Q9Y263,Q92889,Q96GC9,Q9NZJ7,Q86UE4,Q99623,P10619,Q07820,Q8TEY7
Processes and pathways
GO Biological process
msigdb_gobp
3,131,394,132,266,14,408,144,275,23,397,151,37,293,167,431,41,424,420,307,53,309,55,56,57,313,327,325,322,122,98,243,248,245,251,389
2150,465,1677,266,584,1632,56,151,717,2604,475,1486,2656,1882,57,2390,623,739,565,55,1310,1399,420,487,1921,132,1155,2287,1736,1351,37,245,1850,864,144,1113,1923,1195,1114,2674,694,674,23,2210,14,313,1314,2788,1119,275,1451,1856,397,307,1124,932,1241,2729,424,1548,538,2292,1209,1551,1936,1322,251,1166,1864,1249,1555,17...
-0.471476648351972,0.49962950681326135,-0.2459980349044931,0.9473814090258249,0.34515985407120203,-0.22747447582986668,2.916446962695746,1.617013061048013,0.22309537077734548,-0.8611490148593872,0.48260039141735633,-0.17214318056581754,-0.9816645976999411,-0.33922324092093464,2.8772408406430023,-0.6251920440620977,0.31...
2,812
Abnormal circulating cholesterol concentration
12
29
2.493385
0.012653
Q15800,O75431,Q9NZJ7,P07602,P37268,Q14739,Q8N511,Q9NVI7,P42858,Q15392,P06737,P02545
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
129,65,98,132,38,235,12,273,275,150,372,371
65,371,372,132,2754,38,275,816,533,748,655,2509,1603,2341,2629,235,150,657,129,1418,2057,12,1903,1226,1227,273,98,857,430
2.6920877924017246,0.6346847947097649,0.6346847947097649,1.7510917082093325,-1.4391379895738585,3.4735930042919643,0.9149813991987668,0.15256614703595497,0.4141504853427531,0.2055167698607001,0.2756186567217988,-0.7423429355985278,-0.2089909446401189,-0.5865005631893707,-0.9011281689088609,1.0917382653656786,1.64697976...
2,812
Porphyrin and chlorophyll metabolism
6
12
2.48726
0.012873
P09601,P36551,Q7KZN9,Q5JPH6,P22830,P30519
Processes and pathways
KEGG Pathways
msigdb_kegg
37,197,133,305,126,31
2286,354,1112,37,126,1044,31,197,1122,472,305,133
-0.5479853796195989,0.6848001484363205,-0.008258738440055532,3.4735930042919643,1.8247352597370783,0.027739919068620857,3.80008400175991,1.280653405466914,-0.008258738440055532,0.49962950681326135,0.8334597491992295,1.7510917082093325
2,812
Abnormal biliary tract morphology
10
21
2.484504
0.012973
Q9NZJ7,P07602,P09601,Q92889,Q10713,Q14739,Q5XKP0,O43681,P04062,Q14108
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
98,132,37,322,138,235,212,182,55,62
182,371,55,132,37,638,1689,1641,471,138,62,235,212,322,1619,2303,948,98,2671,1810,2387
1.373639236931527,0.6346847947097649,2.9684696908889308,1.7510917082093325,3.4735930042919643,0.2930561203226198,-0.2459980349044931,-0.22747447582986668,0.49962950681326135,1.7362913212685769,2.7453620538410717,1.0917382653656786,1.186694264872841,0.7676975668159858,-0.2089909446401189,-0.5479853796195989,0.0814578040...
2,812
Bulbar signs
6
11
2.48363
0.013005
Q9NZJ7,P07602,P03886,Q99720,O43681,P04062
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
98,132,100,135,182,55
182,100,55,1036,132,744,1786,1618,135,98,325
1.373639236931527,2.1984168906874886,2.9684696908889308,0.027739919068620857,1.7510917082093325,0.2055167698607001,-0.283166031185393,-0.2089909446401189,1.7510917082093325,2.226542769012561,0.7676975668159858
2,812
Organophosphate ester transport
14
23
2.482749
0.013037
P33527,Q8WTV0,P12236,P08183,Q6NUK1,Q4KMQ2,Q8TB61,Q9H2D1,P22307,P05141,Q96GC9,Q9HC21,Q9BZF1,Q14108
Processes and pathways
GO Biological process
msigdb_gobp
411,67,261,71,387,522,79,48,551,487,122,350,349,62
586,487,71,864,261,2409,551,411,817,2509,1130,62,522,387,1255,1947,79,67,122,349,48,350,2204
0.34515985407120203,0.46553808003374114,2.665336704465738,0.11708504290317308,0.9635371984080219,-0.6446044732945461,0.3969539001942955,0.5842822509907212,0.15256614703595497,-0.7423429355985278,-0.008258738440055532,2.7453620538410717,0.4313132764939044,0.6179160419293773,-0.06254040557376016,-0.35799118461648044,2.48...
2,812
Visual field defect
10
41
2.480489
0.01312
Q9Y287,P03886,P01889,Q8NHS3,Q969G3,P04439,Q8WWV3,O75381,P40855,Q9H061
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
193,100,201,41,268,204,16,145,345,30
1529,465,2246,1151,343,477,145,623,590,201,100,2507,204,1780,1238,1443,2252,1925,1088,345,1361,1596,1857,1975,2128,521,779,729,2445,1254,41,882,16,1516,268,1102,2230,1470,30,2464,193
-0.1905472446215371,0.49962950681326135,-0.5287933290146903,-0.026314622385095934,0.7014420888364408,0.48260039141735633,1.661926099494074,0.31045870212056503,0.34515985407120203,1.2494429822888136,2.1984168906874886,-0.7423429355985278,1.218123559434321,-0.283166031185393,-0.06254040557376016,-0.15377855875444413,-0.5...
2,812
Decreased activity of mitochondrial complex i
7
27
2.479688
0.01315
O96000,P03886,Q70HW3,Q9H845,Q9Y6M9,O43676,Q9UBX3
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
225,100,5,265,231,10,59
10,1276,477,1306,587,597,225,100,2084,1971,1642,578,2008,305,2445,5,417,2302,461,1664,1223,265,1525,59,993,1482,231
4.761828046714546,-0.0807106708667228,0.48260039141735633,-0.0989194316256046,0.34515985407120203,0.3278265608377056,1.1393423790368928,2.1984168906874886,-0.4334795450313125,-0.3768005767007224,-0.22747447582986668,0.3624587383041505,-0.3956516265185736,0.8334597491992295,-0.664061673412729,5.017262595389153,0.5842822...
2,812
Cardiac muscle contraction
9
23
2.477526
0.01323
Q9UDW1,O14949,P09493,P14406,P16615,P13073,P47985,P05023,P22695
Processes and pathways
KEGG Pathways
msigdb_kegg
64,70,319,28,144,146,147,184,250
70,590,184,467,1036,723,319,844,1156,146,28,344,966,144,673,250,605,147,2652,1697,479,2601,64
2.665336704465738,0.34515985407120203,1.3582082159271402,0.49962950681326135,0.027739919068620857,0.22309537077734548,0.7676975668159858,0.13484377635600422,-0.026314622385095934,1.661926099494074,3.941725005389792,0.7014420888364408,0.06358895367080376,1.6768478836617977,0.2581461514602102,1.0118291637604662,0.3278265...
2,812
Ascites
7
23
2.47415
0.013355
Q92889,P08236,Q14739,Q13510,P04062,O15118,Q14108
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
322,354,235,85,55,56,62
56,995,1881,1309,55,354,1037,1039,1404,471,2509,1054,1601,377,1455,1746,85,62,235,1096,322,948,2387
2.916446962695746,0.04568305057423946,-0.33922324092093464,-0.0989194316256046,2.9684696908889308,0.6848001484363205,0.027739919068620857,0.027739919068620857,-0.13545318694325917,0.49962950681326135,-0.7423429355985278,0.027739919068620857,-0.2089909446401189,0.6346847947097649,-0.15377855875444413,-0.2645618200989318...
2,812
Progressive neurologic deterioration
9
19
2.466887
0.013629
P16278,Q9Y287,Q9NZJ7,P07602,Q10713,Q5XKP0,O43681,P04062,P54802
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
256,193,98,132,138,212,182,55,152
182,55,132,2332,256,1442,410,2252,2087,152,332,932,138,1374,212,2053,1989,98,193
1.373639236931527,2.9684696908889308,1.7510917082093325,-0.5865005631893707,0.995760955144229,-0.15377855875444413,0.5842822509907212,-0.5287933290146903,-0.4334795450313125,1.617013061048013,0.7346320169701449,0.08145780404230812,1.7362913212685769,-0.11716687434726772,1.186694264872841,-0.41454454507068694,-0.3768005...
2,812
Lipoprotein metabolic process
6
14
2.454734
0.014099
O75608,Q9NUJ1,Q8N2K0,P04062,Q9BQE5,P50897
Processes and pathways
GO Biological process
msigdb_gobp
33,254,247,55,26,95
336,1234,33,55,2592,95,778,247,756,1465,617,26,2141,254
0.7180526668602384,-0.06254040557376016,3.75240658285758,2.9684696908889308,-0.8412307870350623,2.226542769012561,0.18790247626968237,1.0278684187598215,0.2055167698607001,-0.15377855875444413,0.3278265608377056,4.069774341527857,-0.45245684076640463,1.0118291637604662
2,812
Protein transmembrane import into intracellular organelle
6
12
2.453423
0.01415
O60830,Q99595,O75381,Q15388,O95831,O14925
Processes and pathways
GO Biological process
msigdb_gobp
0,1,145,348,158,255
255,383,0,145,528,158,768,1401,348,704,1,785
0.995760955144229,0.6179160419293773,5.214962353364934,1.661926099494074,0.4141504853427531,1.5567809266545096,0.18790247626968237,-0.13545318694325917,0.7014420888364408,0.24063844353304098,5.214962353364934,0.18790247626968237
2,812