term
stringlengths 2
121
| overlap
int64 6
281
| setsize
int64 7
499
| score
float64 1.96
10.6
| pval
float64 0
0.05
| edge
stringlengths 41
1.97k
| type
stringclasses 5
values | subtype
stringclasses 24
values | subtype_key
stringclasses 24
values | edge_idxs
stringlengths 11
1.17k
| ann_idxs
stringlengths 19
2.31k
| ann_vals
stringlengths 124
9.94k
| sig_size
int64 2.2k
3.73k
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mitochondrial substrate/solute carrier [IPR018108]
| 12
| 19
| 2.921662
| 0.003482
|
Q9NZJ7,Q70HW3,P12236,Q6NUK1,Q9BQT8,Q02978,Q9H2D1,Q9Y619,Q9Y6C9,Q9HC21,O43772,Q9UBX3
|
Sequence
|
InterPro Repeat
|
interpro_repeat
|
98,5,261,387,77,271,48,119,153,350,89,59
|
89,586,861,487,864,261,607,975,271,387,5,77,48,350,98,59,430,119,153
|
2.2964854074361383,0.34515985407120203,0.11708504290317308,0.46553808003374114,0.11708504290317308,0.9635371984080219,0.3278265608377056,0.06358895367080376,0.9311961834886229,0.6179160419293773,5.017262595389153,2.5440011741485096,3.110074180270112,0.7014420888364408,2.226542769012561,2.8641358146662417,0.5674169318211052,1.8832252764522284,1.617013061048013
| 2,812
|
Receptor
| 11
| 34
| 2.918625
| 0.003516
|
Q9Y5M8,Q9NS69,O15173,Q8WTV0,Q99720,Q14739,P35613,O00264,O15118,P15260,Q14108
|
Functions
|
Protein Atlas Molecular function
|
protein_atlas_molecular_function
|
66,2,36,67,135,235,121,118,56,185,62
|
118,56,36,2536,1081,455,1350,2363,925,1537,1084,566,2635,693,185,2569,386,121,2594,2722,825,62,235,611,612,67,1518,1952,248,135,2,2114,66,2329
|
1.8832252764522284,2.916446962695746,3.498161016050837,-0.762027572092384,0.009759382165723819,0.5166255731433357,-0.11716687434726772,-0.6058241514720926,0.08145780404230812,-0.1905472446215371,0.009759382165723819,0.37972336891623004,-0.9211896151418975,0.24063844353304098,1.3582082159271402,-0.801535746199426,0.6179160419293773,1.8686378297720425,-0.8412307870350623,-1.1864793952065424,0.15256614703595497,2.7453620538410717,1.0917382653656786,0.3278265608377056,0.3278265608377056,2.678721796351966,-0.17214318056581754,-0.35799118461648044,1.0278684187598215,1.7510917082093325,5.214962353364934,-0.4334795450313125,2.6920877924017246,-0.5672210487658126
| 2,812
|
Ion transport
| 69
| 187
| 2.917916
| 0.003524
|
P20020,P07602,Q70HW3,Q7KZN9,Q9UHG3,Q9Y4W6,P12236,Q6NUK1,Q8NE01,Q4KMQ2,Q01650,P30536,Q02978,P16615,P45880,P13073,P47985,P42858,Q9Y4C2,P21796,P51809,P78417,P56385,P33527,O75964,Q9Y277,O15173,Q14728,Q9UNH7,Q9UJS0,P61421,Q6P4A7,Q9H2D1,O14936,O43681,P24539,O75844,Q9UBX3,Q9HD20,P05023,P36543,Q9UDW1,Q15041,P30825,P56134,P08183,Q9BQT8,Q8TB61,O00429,P05026,Q9C0H2,O43772,Q99623,O95202,Q9HC21,O43865,Q9NZJ7,Q9UM00,O76024,Q7L0J3,Q9H2H9,Q96ES6,P05141,P51790,Q13423,Q9Y619,Q96GC9,Q13555,Q8NEW0
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
257,132,5,133,7,526,261,387,267,522,520,14,271,144,17,146,147,275,409,23,397,414,413,411,34,164,36,163,431,430,424,46,48,299,182,435,57,59,60,184,313,64,195,386,447,71,77,79,465,467,90,89,248,92,350,476,98,226,227,495,239,112,487,242,510,119,122,511,125
|
2769,807,465,1679,1680,299,36,182,1846,89,586,476,997,691,1583,1276,1392,1486,2533,861,57,1034,598,34,227,92,768,590,2536,1111,1236,184,467,487,1081,1440,843,2312,1921,132,1082,71,924,723,1156,2688,863,602,864,261,146,964,638,144,1113,2158,2751,257,1239,673,694,674,2538,1924,23,435,1086,2160,2210,2289,904,1591,14,867,386,605,1046,411,1925,1927,532,313,1314,275,17,1408,2254,147,972,1546,242,397,607,1819,1201,2652,2258,1697,1051,447,413,2044,424,870,537,727,414,975,1209,1551,520,1822,271,569,2542,2782,1457,1130,2368,1323,1166,510,2546,511,163,1828,195,778,1980,611,1982,522,2661,387,2054,46,1134,5,133,495,1514,1902,1098,1947,267,125,79,2601,1518,112,122,887,834,2737,2139,248,1224,77,2324,90,1336,2748,48,239,2064,760,350,60,98,2280,59,64,1477,7,787,430,859,2146,226,2328,431,164,1149,409,526,119,1340
|
-1.6338631244210937,0.15256614703595497,0.49962950681326135,-0.2459980349044931,-0.2459980349044931,0.8334597491992295,3.498161016050837,1.373639236931527,-0.3204965379073243,2.2964854074361383,0.34515985407120203,0.48260039141735633,0.04568305057423946,0.24063844353304098,-0.2089909446401189,-0.0807106708667228,-0.13545318694325917,-0.17214318056581754,-0.762027572092384,0.11708504290317308,2.8772408406430023,0.027739919068620857,0.3278265608377056,3.55930743245453,1.1235025176038205,2.2545833119587817,0.18790247626968237,0.34515985407120203,-0.762027572092384,-0.008258738440055532,-0.06254040557376016,1.3582082159271402,0.49962950681326135,0.46553808003374114,0.009759382165723819,-0.15377855875444413,0.13484377635600422,-0.5672210487658126,-0.35799118461648044,1.7510917082093325,0.009759382165723819,2.665336704465738,0.08145780404230812,0.22309537077734548,-0.026314622385095934,-1.062986143976836,0.11708504290317308,0.3278265608377056,0.11708504290317308,0.9635371984080219,1.661926099494074,0.06358895367080376,0.2930561203226198,1.6768478836617977,-0.008258738440055532,-0.471476648351972,-1.4177846515000923,0.995760955144229,-0.06254040557376016,0.2581461514602102,0.24063844353304098,0.2581461514602102,-0.762027572092384,-0.35799118461648044,4.127427393456283,0.5505191412386632,0.009759382165723819,-0.471476648351972,-0.5096446720406466,-0.5479853796195989,0.09928977608158417,-0.2089909446401189,4.433024287479104,0.11708504290317308,0.6179160419293773,0.3278265608377056,0.027739919068620857,0.5842822509907212,-0.35799118461648044,-0.35799118461648044,0.4141504853427531,0.7841840310190734,-0.0989194316256046,0.9149813991987668,4.287071828555498,-0.13545318694325917,-0.5287933290146903,1.661926099494074,0.06358895367080376,-0.1905472446215371,1.043878838847843,0.6011152406986369,0.3278265608377056,-0.30181086948961583,-0.044408450650093925,-0.9614575627830952,-0.5287933290146903,-0.2459980349044931,0.027739919068620857,0.5335887363165991,0.5842822509907212,-0.41454454507068694,0.5674169318211052,0.11708504290317308,0.4141504853427531,0.22309537077734548,0.5842822509907212,0.06358895367080376,-0.044408450650093925,-0.1905472446215371,0.4313132764939044,-0.30181086948961583,0.9311961834886229,0.37972336891623004,-0.762027572092384,-1.9009500015564165,-0.15377855875444413,-0.008258738440055532,-0.6058241514720926,-0.0989194316256046,-0.026314622385095934,0.44844242471808454,-0.762027572092384,0.44844242471808454,1.5265139768993863,-0.30181086948961583,1.3117556902397782,0.18790247626968237,-0.3768005767007224,0.3278265608377056,-0.3768005767007224,0.4313132764939044,-0.9816645976999411,0.6179160419293773,-0.41454454507068694,3.1483293001683137,-0.008258738440055532,5.017262595389153,1.7510917082093325,0.46553808003374114,-0.17214318056581754,-0.33922324092093464,0.009759382165723819,-0.35799118461648044,0.9473814090258249,1.8540270682769622,2.489563986964071,-0.8412307870350623,-0.17214318056581754,1.984691640902663,1.8686378297720425,0.11708504290317308,0.15256614703595497,-1.248922783915979,-0.45245684076640463,1.0278684187598215,-0.044408450650093925,2.5440011741485096,-0.5672210487658126,2.2964854074361383,-0.0989194316256046,-1.375243635959107,3.110074180270112,1.0758136453276277,-0.41454454507068694,0.2055167698607001,0.7014420888364408,2.8378709383397114,2.226542769012561,-0.5287933290146903,2.8641358146662417,2.732071824115165,-0.15377855875444413,4.985687894221841,0.18790247626968237,0.5674169318211052,0.13484377635600422,-0.45245684076640463,1.1393423790368928,-0.5672210487658126,0.5674169318211052,1.5265139768993863,-0.008258738440055532,0.6011152406986369,0.4313132764939044,1.8832252764522284,-0.0989194316256046
| 2,812
|
Dementia
| 18
| 56
| 2.907028
| 0.003649
|
Q9Y487,Q9Y287,O76024,P07602,Q92889,P03886,Q9NZJ7,P54886,P17900,P42858,Q13510,O43681,P04062,O15118,Q5JTZ9,Q9NQZ5,P36543,Q14108
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
3,193,227,132,322,100,98,332,270,275,85,182,55,56,187,341,313,62
|
465,1342,56,182,343,2077,227,768,590,100,55,842,2680,132,2041,1780,270,1442,410,1587,1969,2252,847,744,313,1314,275,1786,2435,332,932,2509,1936,2542,876,1249,85,62,1058,187,1901,1137,707,322,943,1988,2610,2139,341,98,716,1957,1809,193,2590,3
|
0.49962950681326135,-0.11716687434726772,2.916446962695746,1.373639236931527,0.7014420888364408,-0.4334795450313125,1.1235025176038205,0.18790247626968237,0.34515985407120203,2.1984168906874886,2.9684696908889308,0.13484377635600422,-1.0425811965372063,1.7510917082093325,-0.41454454507068694,-0.283166031185393,0.9311961834886229,-0.15377855875444413,0.5842822509907212,-0.2089909446401189,-0.3768005767007224,-0.5287933290146903,0.13484377635600422,0.2055167698607001,0.7841840310190734,-0.0989194316256046,0.9149813991987668,-0.283166031185393,-0.664061673412729,0.7346320169701449,0.08145780404230812,-0.7423429355985278,-0.35799118461648044,-0.762027572092384,0.11708504290317308,-0.06254040557376016,2.393526363136978,2.7453620538410717,0.027739919068620857,1.3582082159271402,-0.33922324092093464,-0.008258738440055532,0.24063844353304098,0.7676975668159858,0.08145780404230812,-0.3768005767007224,-0.8611490148593872,-0.45245684076640463,0.7180526668602384,2.226542769012561,0.24063844353304098,-0.35799118461648044,-0.283166031185393,1.3272665469737428,-0.8213597823323313,5.214962353364934
| 2,812
|
primary active transporter
| 8
| 21
| 2.9063
| 0.003657
|
Q9NS69,Q9BUN8,Q6P4A7,O60888,P16615,O75381,P05023,Q8N4H5
|
Functions
|
Panther Protein class
|
panther_protein_class
|
2,136,46,109,144,145,184,29
|
109,145,528,768,184,467,1190,144,257,1697,348,611,46,29,1947,834,136,987,760,785,2
|
2.0421722903154036,1.661926099494074,0.4141504853427531,0.18790247626968237,1.3582082159271402,0.49962950681326135,-0.044408450650093925,1.6768478836617977,0.995760955144229,-0.2459980349044931,0.7014420888364408,0.3278265608377056,3.1483293001683137,3.882958953414374,-0.35799118461648044,0.15256614703595497,1.7510917082093325,0.06358895367080376,0.2055167698607001,0.18790247626968237,5.214962353364934
| 2,812
|
Hormone metabolic process
| 8
| 28
| 2.905872
| 0.003662
|
Q9HB40,P42892,P16435,P30536,O95470,O75844,P05023,Q06124
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
217,171,108,14,113,57,184,189
|
1154,57,1438,113,184,1349,1350,693,1637,108,14,171,1411,471,189,221,629,512,614,481,882,1519,887,1989,217,857,1577,342
|
-0.026314622385095934,2.8772408406430023,-0.15377855875444413,1.970265053697904,1.3582082159271402,-0.11716687434726772,-0.11716687434726772,0.24063844353304098,-0.22747447582986668,2.0850480342379543,4.433024287479104,1.4656744516817248,-0.13545318694325917,0.49962950681326135,1.3427506872987998,1.1551542156307362,0.31045870212056503,0.44844242471808454,0.3278265608377056,0.48260039141735633,0.11708504290317308,-0.17214318056581754,0.11708504290317308,-0.3768005767007224,1.1709381402052799,0.13484377635600422,-0.1905472446215371,0.7180526668602384
| 2,812
|
Organic acid transmembrane transport
| 13
| 27
| 2.902185
| 0.003706
|
P23786,P33527,Q15041,P08183,P30825,Q9BQT8,Q02978,Q9H2D1,Q9H2H9,P31751,Q9Y619,O43772,Q9UBX3
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
128,411,195,71,386,77,271,48,239,373,119,89,59
|
89,861,1034,1081,71,924,2688,128,904,386,373,506,411,607,1819,520,271,195,611,834,77,48,239,760,59,430,119
|
2.2964854074361383,0.11708504290317308,0.027739919068620857,0.009759382165723819,2.665336704465738,0.08145780404230812,-1.062986143976836,1.780620541054555,0.09928977608158417,0.6179160419293773,0.6346847947097649,0.44844242471808454,0.5842822509907212,0.3278265608377056,-0.30181086948961583,0.4313132764939044,0.9311961834886229,1.3117556902397782,0.3278265608377056,0.15256614703595497,2.5440011741485096,3.110074180270112,1.0758136453276277,0.2055167698607001,2.8641358146662417,0.5674169318211052,1.8832252764522284
| 2,812
|
Oxidoreduction driven active transmembrane transporter activity
| 8
| 27
| 2.899997
| 0.003732
|
Q9UDW1,O96000,P03886,Q7KZN9,Q9P0J0,O43676,P13073,P47985
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
64,225,100,133,170,10,146,147
|
1679,651,10,1276,477,1306,587,503,1307,902,225,590,100,723,1156,146,2084,673,1971,605,147,797,1982,133,170,64,231
|
-0.2459980349044931,0.2756186567217988,4.761828046714546,-0.0807106708667228,0.48260039141735633,-0.0989194316256046,0.34515985407120203,0.44844242471808454,-0.0989194316256046,0.09928977608158417,1.1393423790368928,0.34515985407120203,2.1984168906874886,0.22309537077734548,-0.026314622385095934,1.661926099494074,-0.4334795450313125,0.2581461514602102,-0.3768005767007224,0.3278265608377056,1.661926099494074,0.17025232429825055,-0.3768005767007224,1.7510917082093325,1.4809227807404823,2.732071824115165,1.1235025176038205
| 2,812
|
Regulation of lipid biosynthetic process
| 7
| 26
| 2.891244
| 0.003837
|
P49748,Q8WTV0,P16435,P30536,Q8NF37,Q13510,P05023
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
160,67,108,14,179,85,184
|
1154,636,1000,219,588,959,1111,184,1350,385,108,1922,14,1119,160,1166,85,2220,179,67,1221,379,2450,857,1477,1576
|
-0.026314622385095934,0.2930561203226198,0.04568305057423946,1.1551542156307362,0.34515985407120203,0.06358895367080376,-0.008258738440055532,1.3582082159271402,-0.11716687434726772,0.6179160419293773,2.0850480342379543,-0.35799118461648044,4.433024287479104,-0.008258738440055532,1.541660105153763,-0.026314622385095934,2.393526363136978,-0.5096446720406466,1.4044221691939036,2.678721796351966,-0.044408450650093925,0.6346847947097649,-0.664061673412729,0.13484377635600422,-0.15377855875444413,-0.1905472446215371
| 2,812
|
Tetrapyrrole binding
| 8
| 14
| 2.889268
| 0.003861
|
O15173,P09601,Q7KZN9,Q16850,O00264,O43169,Q9H7Z7,P30519
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
36,37,133,42,118,22,94,31
|
118,36,22,723,37,2728,31,42,133,155,1716,94,991,2701
|
1.8832252764522284,3.498161016050837,4.127427393456283,0.22309537077734548,3.4735930042919643,-1.2280559205447314,3.80008400175991,3.2495966741269706,1.7510917082093325,1.5869470337151412,-0.2459980349044931,2.2545833119587817,0.06358895367080376,-1.0834412629096282
| 2,812
|
Huntingtons disease
| 24
| 73
| 2.883155
| 0.003937
|
P12236,O43676,P45880,P13073,P47985,P42858,P21796,P14406,P21912,Q9Y277,Q13561,P24539,P63010,Q9UDW1,O14949,P14927,O15514,O96000,O75306,Q9Y6M9,P05141,Q00059,P22695,Q08752
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
261,10,17,146,147,275,23,28,410,164,291,435,437,64,70,344,223,225,477,231,487,377,250,509
|
1679,70,223,651,10,1276,477,1306,587,598,1686,503,1307,902,2648,225,590,1920,1399,487,843,723,672,926,844,1156,864,261,146,28,344,966,770,1538,2084,673,23,410,250,435,1968,2160,2210,1971,930,2252,605,532,275,17,147,972,2490,2092,1206,437,377,1551,509,1415,291,1058,1980,797,1982,757,2179,1382,64,2671,1267,164,231
|
-0.2459980349044931,2.665336704465738,1.1393423790368928,0.2756186567217988,4.761828046714546,-0.0807106708667228,0.48260039141735633,-0.0989194316256046,0.34515985407120203,0.3278265608377056,-0.2459980349044931,0.44844242471808454,-0.0989194316256046,0.09928977608158417,-0.9614575627830952,1.1393423790368928,0.34515985407120203,-0.35799118461648044,-0.13545318694325917,0.46553808003374114,0.13484377635600422,0.22309537077734548,0.2581461514602102,0.08145780404230812,0.13484377635600422,-0.026314622385095934,0.11708504290317308,0.9635371984080219,1.661926099494074,3.941725005389792,0.7014420888364408,0.06358895367080376,0.18790247626968237,-0.1905472446215371,-0.4334795450313125,0.2581461514602102,4.127427393456283,0.5842822509907212,1.0118291637604662,0.5505191412386632,-0.3768005767007224,-0.471476648351972,-0.5096446720406466,-0.3768005767007224,0.08145780404230812,-0.5287933290146903,0.3278265608377056,0.4141504853427531,0.9149813991987668,4.287071828555498,1.661926099494074,0.06358895367080376,-0.7227042705874989,-0.4334795450313125,-0.044408450650093925,0.5505191412386632,0.6346847947097649,-0.1905472446215371,0.44844242471808454,-0.13545318694325917,0.8498241944386672,0.027739919068620857,-0.3768005767007224,0.17025232429825055,-0.3768005767007224,0.2055167698607001,-0.471476648351972,-0.11716687434726772,2.732071824115165,-1.0019206995296568,-0.06254040557376016,1.5265139768993863,1.1235025176038205
| 2,812
|
Alcohol metabolic process
| 19
| 74
| 2.873962
| 0.004054
|
Q15800,Q10713,Q15392,O15269,Q9BQE5,P48449,P49748,P37268,Q16850,P48735,P04062,O15118,Q8WTV0,Q13510,Q14849,P51648,O76054,Q14739,P16435
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
129,138,150,151,26,154,160,38,42,173,55,56,67,85,221,91,219,235,108
|
2035,56,151,717,956,1151,1234,636,1000,219,588,1345,961,1636,2742,55,433,602,637,320,1402,1637,108,1041,1443,1541,2754,2778,38,1854,1362,154,173,160,1596,748,2435,91,519,822,457,2509,1650,555,2638,1603,138,1166,85,2791,1416,241,235,221,150,657,129,1168,42,512,755,614,882,67,2139,2230,26,2233,2027,2383,2708,857,1839,342
|
-0.41454454507068694,2.916446962695746,1.617013061048013,0.22309537077734548,0.06358895367080376,-0.026314622385095934,-0.06254040557376016,0.2930561203226198,0.04568305057423946,1.1551542156307362,0.34515985407120203,-0.11716687434726772,0.06358895367080376,-0.22747447582986668,-1.2908152269601356,2.9684696908889308,0.5505191412386632,0.3278265608377056,0.2930561203226198,0.7676975668159858,-0.13545318694325917,-0.22747447582986668,2.0850480342379543,0.027739919068620857,-0.15377855875444413,-0.1905472446215371,-1.4391379895738585,-1.8333497016212914,3.4735930042919643,-0.3204965379073243,-0.11716687434726772,1.601992510014427,1.435100304078915,1.541660105153763,-0.2089909446401189,0.2055167698607001,-0.664061673412729,2.2685717667150977,0.4313132764939044,0.15256614703595497,0.5166255731433357,-0.7423429355985278,-0.22747447582986668,0.3969539001942955,-0.9211896151418975,-0.2089909446401189,1.7362913212685769,-0.026314622385095934,2.393526363136978,-2.318923044825233,-0.13545318694325917,1.0598605419718725,1.0917382653656786,1.1551542156307362,1.6469797626441487,0.2756186567217988,1.780620541054555,-0.026314622385095934,3.2495966741269706,0.44844242471808454,0.2055167698607001,0.3278265608377056,0.11708504290317308,2.678721796351966,-0.45245684076640463,-0.5096446720406466,4.069774341527857,-0.5096446720406466,-0.3956516265185736,-0.6058241514720926,-1.1245031466065663,0.13484377635600422,-0.30181086948961583,0.7180526668602384
| 2,812
|
Electron transport chain
| 13
| 62
| 2.871013
| 0.004092
|
Q9UDW1,O96000,P03886,Q7KZN9,O14949,O43819,Q9P0J0,O43676,P16435,Q9H3K2,P13073,P47985,P04062
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
64,225,100,133,70,200,170,10,108,207,146,147,55
|
1679,70,596,956,651,10,200,1151,1276,477,1306,587,861,503,1307,902,225,2535,590,100,55,1920,433,455,723,962,1156,637,146,965,2208,344,1637,966,108,2084,673,410,2249,1639,1971,2004,2252,1011,1362,147,1702,877,1327,2608,797,1982,1133,133,2139,2202,207,170,64,430,993,231
|
-0.2459980349044931,2.665336704465738,0.3278265608377056,0.06358895367080376,0.2756186567217988,4.761828046714546,1.2494429822888136,-0.026314622385095934,-0.0807106708667228,0.48260039141735633,-0.0989194316256046,0.34515985407120203,0.11708504290317308,0.44844242471808454,-0.0989194316256046,0.09928977608158417,1.1393423790368928,-0.762027572092384,0.34515985407120203,2.1984168906874886,2.9684696908889308,-0.35799118461648044,0.5505191412386632,0.5166255731433357,0.22309537077734548,0.06358895367080376,-0.026314622385095934,0.2930561203226198,1.661926099494074,0.06358895367080376,-0.5096446720406466,0.7014420888364408,-0.22747447582986668,0.06358895367080376,2.0850480342379543,-0.4334795450313125,0.2581461514602102,0.5842822509907212,-0.5287933290146903,-0.22747447582986668,-0.3768005767007224,-0.3956516265185736,-0.5287933290146903,0.04568305057423946,-0.11716687434726772,1.661926099494074,-0.2459980349044931,0.11708504290317308,-0.0989194316256046,-0.8611490148593872,0.17025232429825055,-0.3768005767007224,-0.008258738440055532,1.7510917082093325,-0.45245684076640463,-0.490539185592664,1.218123559434321,1.4809227807404823,2.732071824115165,0.5674169318211052,0.06358895367080376,1.1235025176038205
| 2,812
|
Cognitive impairment
| 45
| 151
| 2.860638
| 0.004228
|
P16278,Q9Y487,P07602,Q99720,Q10713,Q969G3,P17900,O75381,P42858,Q9Y2R0,P21964,Q03164,P54802,Q9BQE5,Q15437,O95831,P21912,P49327,Q8NHS3,Q6DKK2,O43681,P04062,O15118,Q5JTZ9,Q9NZ08,P36543,Q14108,Q9Y287,Q9Y263,Q92889,O43819,P01889,P54886,Q5XKP0,Q13510,O75503,Q9NQZ5,P40855,O60313,P50897,Q9NZJ7,O76024,P03886,O95470,Q9Y619
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
256,3,132,135,138,268,270,145,275,20,149,400,152,26,415,158,410,412,41,180,182,55,56,187,317,313,62,193,325,322,200,201,332,212,85,213,341,345,343,95,98,227,100,113,119
|
465,1342,56,182,200,343,2077,477,1344,145,213,227,623,113,158,768,590,201,100,55,842,1399,2124,2680,132,2332,2286,1112,2041,1780,1037,2688,864,256,2568,270,550,1042,1442,2538,1924,410,149,1405,1587,1969,2252,847,2778,744,313,1314,345,1119,2087,275,1786,1361,1642,412,1855,1089,95,748,2435,471,1857,152,332,932,655,2128,870,2509,701,1551,1602,1603,400,1936,1322,2542,1457,138,521,1894,876,2170,1249,85,62,1058,1605,1827,1755,1374,415,729,1289,187,2445,212,180,2053,913,1760,1901,2619,1515,1137,41,1873,707,322,943,268,2302,1988,2610,1102,2139,1989,135,26,1470,1524,1669,341,947,2110,2277,1071,317,98,716,2239,2034,1957,1478,430,1577,1723,1809,325,193,20,2149,2590,3,526,119
|
0.49962950681326135,-0.11716687434726772,2.916446962695746,1.373639236931527,1.2494429822888136,0.7014420888364408,-0.4334795450313125,0.48260039141735633,-0.11716687434726772,1.661926099494074,1.1709381402052799,1.1235025176038205,0.31045870212056503,1.970265053697904,1.5567809266545096,0.18790247626968237,0.34515985407120203,1.2494429822888136,2.1984168906874886,2.9684696908889308,0.13484377635600422,-0.13545318694325917,-0.45245684076640463,-1.0425811965372063,1.7510917082093325,-0.5865005631893707,-0.5479853796195989,-0.008258738440055532,-0.41454454507068694,-0.283166031185393,0.027739919068620857,-1.062986143976836,0.11708504290317308,0.995760955144229,-0.801535746199426,0.9311961834886229,0.3969539001942955,0.027739919068620857,-0.15377855875444413,-0.762027572092384,-0.35799118461648044,0.5842822509907212,1.6469797626441487,-0.13545318694325917,-0.2089909446401189,-0.3768005767007224,-0.5287933290146903,0.13484377635600422,-1.8333497016212914,0.2055167698607001,0.7841840310190734,-0.0989194316256046,0.7014420888364408,-0.008258738440055532,-0.4334795450313125,0.9149813991987668,-0.283166031185393,-0.11716687434726772,-0.22747447582986668,0.5842822509907212,-0.3204965379073243,0.009759382165723819,2.226542769012561,0.2055167698607001,-0.664061673412729,0.49962950681326135,-0.3204965379073243,1.617013061048013,0.7346320169701449,0.08145780404230812,0.2756186567217988,-0.45245684076640463,0.11708504290317308,-0.7423429355985278,0.24063844353304098,-0.1905472446215371,-0.2089909446401189,-0.2089909446401189,0.6011152406986369,-0.35799118461648044,-0.0989194316256046,-0.762027572092384,-0.15377855875444413,1.7362913212685769,0.4313132764939044,-0.33922324092093464,0.11708504290317308,-0.471476648351972,-0.06254040557376016,2.393526363136978,2.7453620538410717,0.027739919068620857,-0.2089909446401189,-0.30181086948961583,-0.2645618200989318,-0.11716687434726772,0.5842822509907212,0.22309537077734548,-0.0807106708667228,1.3582082159271402,-0.664061673412729,1.186694264872841,1.389043853750546,-0.41454454507068694,0.09928977608158417,-0.2645618200989318,-0.33922324092093464,-0.8811147225178695,-0.17214318056581754,-0.008258738440055532,3.349799142139882,-0.3204965379073243,0.24063844353304098,0.7676975668159858,0.08145780404230812,0.9473814090258249,-0.5479853796195989,-0.3768005767007224,-0.8611490148593872,0.009759382165723819,-0.45245684076640463,-0.3768005767007224,1.7510917082093325,4.069774341527857,-0.15377855875444413,-0.17214318056581754,-0.22747447582986668,0.7180526668602384,0.08145780404230812,-0.4334795450313125,-0.5287933290146903,0.027739919068620857,0.7841840310190734,2.226542769012561,0.24063844353304098,-0.5096446720406466,-0.3956516265185736,-0.35799118461648044,-0.15377855875444413,0.5674169318211052,-0.1905472446215371,-0.2459980349044931,-0.283166031185393,0.7676975668159858,1.3272665469737428,4.150393709731816,-0.45245684076640463,-0.8213597823323313,5.214962353364934,0.4313132764939044,1.8832252764522284
| 2,812
|
Vacuole organization
| 10
| 44
| 2.860431
| 0.004231
|
Q8NHS3,Q8N511,P16615,O14773,O75503,P04062,P54802,Q96GC9,Q14108,P50897
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
41,12,144,148,213,55,152,122,62,95
|
2484,148,2656,213,623,739,55,2312,2332,214,741,144,2674,1119,1451,95,1856,1124,152,1241,1367,538,62,778,2396,2716,1292,1255,439,12,41,1464,2178,122,1988,2029,2141,836,1030,1183,668,1809,1811,1387
|
-0.7227042705874989,1.6469797626441487,-0.9816645976999411,1.1709381402052799,0.31045870212056503,0.2055167698607001,2.9684696908889308,-0.5672210487658126,-0.5865005631893707,1.1709381402052799,0.2055167698607001,1.6768478836617977,-1.0222261408317312,-0.008258738440055532,-0.15377855875444413,2.226542769012561,-0.3204965379073243,-0.008258738440055532,1.617013061048013,-0.06254040557376016,-0.11716687434726772,0.4141504853427531,2.7453620538410717,0.18790247626968237,-0.6251920440620977,-1.1657691353785238,-0.0807106708667228,-0.06254040557376016,0.5505191412386632,4.466400716267569,3.349799142139882,-0.15377855875444413,-0.471476648351972,1.8686378297720425,-0.3768005767007224,-0.3956516265185736,-0.45245684076640463,0.15256614703595497,0.04568305057423946,-0.026314622385095934,0.2756186567217988,-0.283166031185393,-0.283166031185393,-0.11716687434726772
| 2,812
|
Receptor
| 8
| 24
| 2.850377
| 0.004367
|
Q8WTV0,Q9BUN8,Q567V2,Q9UQB8,O75381,A6NIH7,P15260,Q14108
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
67,136,8,44,145,21,185,62
|
21,1150,1635,145,1686,2648,1081,2635,185,2569,234,62,2014,8,1420,67,1799,136,987,1909,1994,1911,736,44
|
4.138917294144107,-0.026314622385095934,-0.22747447582986668,1.661926099494074,-0.2459980349044931,-0.9614575627830952,0.009759382165723819,-0.9211896151418975,1.3582082159271402,-0.801535746199426,1.0917382653656786,2.7453620538410717,-0.3956516265185736,4.900998556422755,-0.13545318694325917,2.678721796351966,-0.283166031185393,1.7510917082093325,0.06358895367080376,-0.33922324092093464,-0.3768005767007224,-0.33922324092093464,0.22309537077734548,3.1864309983263617
| 2,812
|
Abnormal circulating lipid concentration
| 29
| 66
| 2.849671
| 0.004376
|
P23786,Q15800,P07602,Q9H845,Q8N511,Q9NVI7,O75381,P42858,Q15392,P49748,Q9Y4P3,Q9UJS0,P37268,Q16836,O75844,Q9Y285,O75431,P40939,Q03252,O75880,O43772,P40855,Q9NZJ7,Q14739,O95470,P31751,P06737,P02545,P22830
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
128,129,132,265,12,273,145,275,150,160,298,430,38,438,57,318,65,331,458,208,89,345,98,235,113,373,372,371,126
|
2152,1846,89,145,65,597,57,208,113,371,2124,372,132,962,2794,126,128,1159,2042,373,2754,1784,793,38,345,331,275,816,697,160,533,748,471,1975,1820,655,2509,2338,1603,458,2341,2629,235,1288,150,657,129,1418,438,2057,12,1903,1618,1465,2418,1226,265,1227,273,98,857,2639,430,318,298,2387
|
-0.471476648351972,-0.3204965379073243,2.2964854074361383,1.661926099494074,2.6920877924017246,0.3278265608377056,2.8772408406430023,1.2024227010441528,1.970265053697904,0.6346847947097649,-0.45245684076640463,0.6346847947097649,1.7510917082093325,0.06358895367080376,-2.610253866866887,1.8247352597370783,1.780620541054555,-0.026314622385095934,-0.41454454507068694,0.6346847947097649,-1.4391379895738585,-0.283166031185393,0.17025232429825055,3.4735930042919643,0.7014420888364408,0.7346320169701449,0.9149813991987668,0.15256614703595497,0.24063844353304098,1.541660105153763,0.4141504853427531,0.2055167698607001,0.49962950681326135,-0.3768005767007224,-0.30181086948961583,0.2756186567217988,-0.7423429355985278,-0.5865005631893707,-0.2089909446401189,0.5166255731433357,-0.5865005631893707,-0.9011281689088609,1.0917382653656786,-0.0807106708667228,1.6469797626441487,0.2756186567217988,1.780620541054555,-0.13545318694325917,0.5505191412386632,-0.41454454507068694,4.466400716267569,-0.33922324092093464,-0.2089909446401189,-0.15377855875444413,-0.6446044732945461,-0.044408450650093925,0.9635371984080219,-0.044408450650093925,0.9311961834886229,2.226542769012561,0.13484377635600422,-0.9211896151418975,0.5674169318211052,0.7841840310190734,0.8498241944386672,-0.6058241514720926
| 2,812
|
Organelle subcompartment
| 103
| 313
| 2.846798
| 0.004416
|
Q7Z2K6,Q06136,O95772,Q8N511,P07099,O60725,O95197,Q9BQE5,P43307,P30519,Q86XL3,Q9NPR9,P09601,P37268,Q5BJF2,Q16850,Q9BRR6,Q96G23,Q8TCT9,Q9NQC3,P04062,O75844,Q9HD20,Q14108,Q9Y5M8,O00461,Q4ZIN3,P67812,Q8TB61,Q9P2W9,P51648,Q99943,Q9Y282,P16435,O95470,Q9NZ01,Q9BZF3,O00264,Q96GC9,A1L0T0,P35613,Q15629,O15260,Q15800,Q99720,Q9BUN8,Q10713,P16615,Q15392,O15269,P48449,Q96A33,P46977,Q10472,Q96A57,Q9P035,Q07065,Q15005,Q8NF37,O43493,Q9H3N1,Q15041,P01889,Q9Y6K0,P57088,P04439,Q9UBU6,Q9BT22,P51572,Q14849,Q9UM00,O76024,Q6RW13,Q96KC8,Q14739,Q13190,Q14534,Q86UE4,O95070,Q8N2K0,O14681,Q9NPA0,Q9Y3B3,Q70UQ0,Q9Y4P3,O15127,Q96HY6,P27824,Q9NZ08,Q96RQ1,Q9Y3A6,Q10567,Q8N5M9,O43292,Q5VV42,Q9BZH6,Q9Y394,Q9BZF1,Q9UNK0,P52292,Q9Y320,Q9NTJ5,Q969V3
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
6,9,11,12,13,19,25,26,27,31,32,35,37,38,40,42,45,47,49,51,55,57,60,62,66,69,74,75,79,87,91,103,104,108,113,115,117,118,122,120,121,124,127,129,135,136,138,144,150,151,154,157,159,162,169,172,176,178,179,181,190,195,201,202,203,204,210,209,215,221,226,227,229,230,235,233,241,243,244,247,266,281,282,284,298,300,309,310,317,315,326,321,334,336,338,340,342,349,351,359,361,381,380
|
120,2776,118,465,1677,69,2549,738,266,2687,901,635,1632,300,127,151,717,994,336,181,1635,2153,432,476,2406,19,1234,1683,999,1344,2656,636,1999,57,1034,227,2390,588,1488,1001,244,25,2000,113,923,959,466,11,740,1636,201,2742,55,204,504,1346,455,13,2363,1736,672,926,37,591,2635,928,108,144,639,1114,2569,2538,2409,1405,970,2488,310,2316,1445,1407,31,867,1497,506,1010,121,38,422,1886,1543,1119,27,1408,159,1502,154,817,697,625,470,533,1546,1364,1597,215,91,397,359,1124,1453,2256,2336,1696,932,2127,203,2613,1241,1745,2729,1016,535,1317,1367,1242,870,848,1203,776,1861,727,1893,1054,75,2614,2555,1551,399,1603,1700,9,176,2341,162,321,138,1702,2707,2544,2195,425,233,511,1896,62,2457,1556,241,235,426,557,221,1095,178,749,195,778,1559,1980,2219,150,1941,415,124,657,129,1418,42,798,74,629,40,912,427,338,2174,1655,2221,1020,2054,229,571,284,6,1255,661,243,2017,32,2643,1293,1514,247,12,1137,334,1946,755,1947,179,1219,1295,79,882,1762,1565,49,733,1464,2767,1903,2459,1139,2601,379,756,983,758,1519,1465,380,1173,157,169,451,710,47,122,887,309,230,1174,404,497,315,617,1952,135,103,2062,26,45,583,2420,209,2462,136,2324,562,1334,1142,349,117,340,987,2748,2141,190,1105,1227,803,60,1383,281,35,51,2523,990,381,2708,2527,115,317,172,2204,2308,87,1574,857,210,516,2145,445,2186,226,351,1808,668,104,689,361,342,2187,326,282,1812,298,66,806,527,2310,900,202
|
1.8686378297720425,-1.7219202513137202,1.8832252764522284,0.49962950681326135,-0.2459980349044931,2.665336704465738,-0.7817584262207112,0.2055167698607001,0.9473814090258249,-1.062986143976836,0.09928977608158417,0.2930561203226198,-0.22747447582986668,0.8334597491992295,1.780620541054555,1.617013061048013,0.22309537077734548,0.04568305057423946,0.7180526668602384,1.373639236931527,-0.22747447582986668,-0.471476648351972,0.5505191412386632,0.48260039141735633,-0.6446044732945461,4.207574767297518,-0.06254040557376016,-0.2459980349044931,0.04568305057423946,-0.11716687434726772,-0.9816645976999411,0.2930561203226198,-0.3956516265185736,2.8772408406430023,0.027739919068620857,1.1235025176038205,-0.6251920440620977,0.34515985407120203,-0.17214318056581754,0.04568305057423946,1.0278684187598215,4.092876418130871,-0.3956516265185736,1.970265053697904,0.08145780404230812,0.06358895367080376,0.49962950681326135,4.707778885717138,0.2055167698607001,-0.22747447582986668,1.2494429822888136,-1.2908152269601356,2.9684696908889308,1.218123559434321,0.44844242471808454,-0.11716687434726772,0.5166255731433357,4.433024287479104,-0.6058241514720926,-0.2645618200989318,0.2581461514602102,0.08145780404230812,3.4735930042919643,0.34515985407120203,-0.9211896151418975,0.08145780404230812,2.0850480342379543,1.6768478836617977,0.2930561203226198,-0.008258738440055532,-0.801535746199426,-0.762027572092384,-0.6446044732945461,-0.13545318694325917,0.06358895367080376,-0.7227042705874989,0.800639796258553,-0.5672210487658126,-0.15377855875444413,-0.13545318694325917,3.80008400175991,0.11708504290317308,-0.17214318056581754,0.44844242471808454,0.04568305057423946,1.8686378297720425,3.4735930042919643,0.5674169318211052,-0.33922324092093464,-0.1905472446215371,-0.008258738440055532,4.01177866837398,-0.13545318694325917,1.5567809266545096,-0.17214318056581754,1.601992510014427,0.15256614703595497,0.24063844353304098,0.31045870212056503,0.49962950681326135,0.4141504853427531,-0.1905472446215371,-0.11716687434726772,-0.2089909446401189,1.1709381402052799,2.2685717667150977,0.6011152406986369,0.6681267102911925,-0.008258738440055532,-0.15377855875444413,-0.5287933290146903,-0.5865005631893707,-0.2459980349044931,0.08145780404230812,-0.45245684076640463,1.2337969500687216,-0.8811147225178695,-0.06254040557376016,-0.2645618200989318,-1.2280559205447314,0.04568305057423946,0.4141504853427531,-0.0989194316256046,-0.11716687434726772,-0.06254040557376016,0.11708504290317308,0.13484377635600422,-0.044408450650093925,0.18790247626968237,-0.3204965379073243,0.22309537077734548,-0.33922324092093464,0.027739919068620857,2.557560972127124,-0.8811147225178695,-0.7817584262207112,-0.1905472446215371,0.6011152406986369,-0.2089909446401189,-0.2459980349044931,4.772602732969393,1.4197742854475608,-0.5865005631893707,1.5265139768993863,0.7676975668159858,1.7362913212685769,-0.2459980349044931,-1.1245031466065663,-0.762027572092384,-0.490539185592664,0.5674169318211052,1.0917382653656786,0.44844242471808454,-0.33922324092093464,2.7453620538410717,-0.6835638805894443,-0.1905472446215371,1.0598605419718725,1.0917382653656786,0.5674169318211052,0.3969539001942955,1.1551542156307362,0.009759382165723819,1.4044221691939036,0.2055167698607001,1.3117556902397782,0.18790247626968237,-0.1905472446215371,-0.3768005767007224,-0.5096446720406466,1.6469797626441487,-0.35799118461648044,0.5842822509907212,1.8540270682769622,0.2756186567217988,1.780620541054555,-0.13545318694325917,3.2495966741269706,0.17025232429825055,2.611604127146138,0.31045870212056503,3.362250839676791,0.09928977608158417,0.5674169318211052,0.7180526668602384,-0.471476648351972,-0.22747447582986668,-0.5096446720406466,0.04568305057423946,-0.41454454507068694,1.1235025176038205,0.37972336891623004,0.8824626599674397,5.006748745407826,-0.06254040557376016,0.2756186567217988,1.043878838847843,-0.3956516265185736,3.7881866490986087,-0.9412993245634615,-0.0807106708667228,-0.17214318056581754,1.0278684187598215,4.466400716267569,-0.008258738440055532,0.7346320169701449,-0.35799118461648044,0.2055167698607001,-0.35799118461648044,1.4044221691939036,-0.044408450650093925,-0.0807106708667228,2.489563986964071,0.11708504290317308,-0.2645618200989318,-0.1905472446215371,3.097288135737863,0.22309537077734548,-0.15377855875444413,-1.6119966512074293,-0.33922324092093464,-0.6835638805894443,-0.008258738440055532,-0.8412307870350623,0.6346847947097649,0.2055167698607001,0.06358895367080376,0.2055167698607001,-0.17214318056581754,-0.15377855875444413,0.6346847947097649,-0.026314622385095934,1.571876537624149,1.4961454123614193,0.5335887363165991,0.24063844353304098,3.1228430207611986,1.8686378297720425,0.11708504290317308,0.8170649925871301,1.1235025176038205,-0.026314622385095934,0.6011152406986369,0.46553808003374114,0.7841840310190734,0.3278265608377056,-0.35799118461648044,1.7510917082093325,2.1560667669732525,-0.41454454507068694,4.069774341527857,3.161046843731062,0.3624587383041505,-0.6446044732945461,1.2024227010441528,-0.6835638805894443,1.7510917082093325,-0.5672210487658126,0.3969539001942955,-0.0989194316256046,-0.008258738440055532,0.7014420888364408,1.8977894929892263,0.7180526668602384,0.06358895367080376,-1.375243635959107,-0.45245684076640463,1.3427506872987998,0.009759382165723819,-0.044408450650093925,0.17025232429825055,2.8378709383397114,-0.11716687434726772,0.8987369327594061,3.5348955440009098,3.071664222481722,-0.7423429355985278,0.06358895367080376,0.6346847947097649,-1.1245031466065663,-0.7423429355985278,1.970265053697904,0.7841840310190734,1.4504003260418334,-0.490539185592664,-0.5479853796195989,2.3520616312023908,-0.1905472446215371,0.13484377635600422,1.2024227010441528,0.44844242471808454,-0.45245684076640463,0.5505191412386632,-0.471476648351972,1.1393423790368928,0.7014420888364408,-0.283166031185393,0.2756186567217988,2.1560667669732525,0.2581461514602102,0.6681267102911925,0.7180526668602384,-0.471476648351972,0.7676975668159858,0.8987369327594061,-0.283166031185393,0.8498241944386672,2.6920877924017246,0.17025232429825055,0.4313132764939044,-0.5479853796195989,0.11708504290317308,1.2494429822888136
| 2,812
|
Cholesterol binding
| 7
| 14
| 2.844188
| 0.004452
|
O95772,P30536,P45880,Q9BZF3,P21796,O15118,Q14108
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
11,14,17,117,23,56,62
|
56,636,588,11,1082,23,551,14,17,2509,62,221,349,117
|
2.916446962695746,0.2930561203226198,0.34515985407120203,4.707778885717138,0.009759382165723819,4.127427393456283,0.3969539001942955,4.433024287479104,4.287071828555498,-0.7423429355985278,2.7453620538410717,1.1551542156307362,0.7014420888364408,1.8977894929892263
| 2,812
|
Photophobia
| 12
| 36
| 2.831515
| 0.004633
|
Q9Y287,Q9NZJ7,P07602,Q92889,Q10567,P01889,Q13432,P51648,P04439,Q8WWV3,P48449,Q9NZ08
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
193,98,132,322,321,201,234,91,204,16,154,317
|
2484,2245,2246,1151,2154,1777,201,842,204,132,1965,769,550,1238,1042,1116,1088,331,154,412,1596,91,321,234,779,1254,1134,16,1516,1712,322,2464,317,98,193,526
|
-0.7227042705874989,-0.5287933290146903,-0.5287933290146903,-0.026314622385095934,-0.471476648351972,-0.283166031185393,1.2494429822888136,0.13484377635600422,1.218123559434321,1.7510917082093325,-0.3768005767007224,0.18790247626968237,0.3969539001942955,-0.06254040557376016,0.027739919068620857,-0.008258738440055532,0.009759382165723819,0.7346320169701449,1.601992510014427,0.5842822509907212,-0.2089909446401189,2.2685717667150977,0.7676975668159858,1.0917382653656786,0.18790247626968237,-0.06254040557376016,-0.008258738440055532,4.309667504674183,-0.17214318056581754,-0.2459980349044931,0.7676975668159858,-0.6835638805894443,0.7841840310190734,2.226542769012561,1.3272665469737428,0.4313132764939044
| 2,812
|
Establishment of protein localization to membrane
| 19
| 71
| 2.8282
| 0.004681
|
Q9NS69,Q15070,Q8NBU5,Q9Y512,O60725,O14737,Q9NPA0,P43307,Q96A33,O75608,Q9P0J0,O43681,O15118,Q9HD20,Q15041,P40855,P46379,P31751,Q15629
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
2,130,388,142,19,274,281,27,157,33,170,182,56,60,195,345,105,373,124
|
2189,2484,274,1632,56,182,577,19,33,1685,528,959,467,1155,2363,2592,1446,373,1358,1498,345,2161,27,105,1408,625,1856,2093,2613,2729,1017,1317,870,1125,1209,1602,1323,2574,749,195,778,130,124,1418,798,730,912,1870,1293,1946,388,157,1988,2028,2464,2753,2141,836,1105,60,281,2,170,516,1232,1477,2145,1480,1810,409,142
|
-0.490539185592664,-0.7227042705874989,0.9149813991987668,-0.22747447582986668,2.916446962695746,1.373639236931527,0.3624587383041505,4.207574767297518,3.75240658285758,-0.2459980349044931,0.4141504853427531,0.06358895367080376,0.49962950681326135,-0.026314622385095934,-0.6058241514720926,-0.8412307870350623,-0.15377855875444413,0.6346847947097649,-0.11716687434726772,-0.17214318056581754,0.7014420888364408,-0.471476648351972,4.01177866837398,2.1277249347323828,-0.13545318694325917,0.31045870212056503,-0.3204965379073243,-0.4334795450313125,-0.8811147225178695,-1.2280559205447314,0.04568305057423946,-0.0989194316256046,0.11708504290317308,-0.008258738440055532,-0.044408450650093925,-0.2089909446401189,-0.0989194316256046,-0.801535746199426,0.2055167698607001,1.3117556902397782,0.18790247626968237,1.7658680852573057,1.8540270682769622,-0.13545318694325917,0.17025232429825055,0.22309537077734548,0.09928977608158417,-0.3204965379073243,-0.0807106708667228,-0.35799118461648044,0.6179160419293773,1.571876537624149,-0.3768005767007224,-0.3956516265185736,-0.6835638805894443,-1.4177846515000923,-0.45245684076640463,0.15256614703595497,0.009759382165723819,2.8378709383397114,0.8987369327594061,5.214962353364934,1.4809227807404823,0.44844242471808454,-0.044408450650093925,-0.15377855875444413,-0.45245684076640463,-0.15377855875444413,-0.283166031185393,0.6011152406986369,1.721466835279003
| 2,812
|
Protein insertion into membrane
| 9
| 22
| 2.827153
| 0.004696
|
Q9NS69,Q15070,P46379,Q9P0J0,Q9Y512,O14737,O43681,Q15629,Q96A33
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
2,130,105,170,142,274,182,124,157
|
274,182,577,528,1155,2592,1358,105,870,749,130,124,730,912,1870,1946,157,281,2,170,1810,142
|
0.9149813991987668,1.373639236931527,0.3624587383041505,0.4141504853427531,-0.026314622385095934,-0.8412307870350623,-0.11716687434726772,2.1277249347323828,0.11708504290317308,0.2055167698607001,1.7658680852573057,1.8540270682769622,0.22309537077734548,0.09928977608158417,-0.3204965379073243,-0.35799118461648044,1.571876537624149,0.8987369327594061,5.214962353364934,1.4809227807404823,-0.283166031185393,1.721466835279003
| 2,812
|
Macroautophagy
| 23
| 94
| 2.82588
| 0.004715
|
Q9Y487,O14681,Q9Y2S7,P16615,P42858,P21796,P51809,O15269,P09601,Q86VR2,Q9Y5X3,Q9UNH7,Q8NHS3,P61421,Q93050,Q96HY6,P04062,O15118,P36543,Q9Y5K8,Q9Y263,Q99623,Q96GC9
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
3,266,408,144,275,23,397,151,37,293,167,431,41,424,53,309,55,56,313,327,325,248,122
|
2150,266,584,56,151,717,475,1486,2656,1882,2390,623,739,565,55,1310,1399,487,1921,1736,37,864,144,1113,2674,694,674,23,313,1314,1119,275,1451,1856,397,1124,932,1241,424,1548,538,1209,1249,778,2396,683,2617,941,1292,1255,1613,293,439,41,2692,1464,1064,53,2178,2450,2021,122,1024,309,1988,2304,248,2560,944,595,2029,2141,836,2705,1384,990,2033,2565,1957,787,1030,1183,431,668,1304,1809,325,1811,408,1387,3,327,167,900
|
-0.471476648351972,0.9473814090258249,0.34515985407120203,2.916446962695746,1.617013061048013,0.22309537077734548,0.48260039141735633,-0.17214318056581754,-0.9816645976999411,-0.33922324092093464,-0.6251920440620977,0.31045870212056503,0.2055167698607001,0.37972336891623004,2.9684696908889308,-0.0989194316256046,-0.13545318694325917,0.46553808003374114,-0.35799118461648044,-0.2645618200989318,3.4735930042919643,0.11708504290317308,1.6768478836617977,-0.008258738440055532,-1.0222261408317312,0.24063844353304098,0.2581461514602102,4.127427393456283,0.7841840310190734,-0.0989194316256046,-0.008258738440055532,0.9149813991987668,-0.15377855875444413,-0.3204965379073243,0.6011152406986369,-0.008258738440055532,0.08145780404230812,-0.06254040557376016,0.5674169318211052,-0.1905472446215371,0.4141504853427531,-0.044408450650093925,-0.06254040557376016,0.18790247626968237,-0.6251920440620977,0.2581461514602102,-0.8811147225178695,0.08145780404230812,-0.0807106708667228,-0.06254040557376016,-0.2089909446401189,0.8498241944386672,0.5505191412386632,3.349799142139882,-1.062986143976836,-0.15377855875444413,0.027739919068620857,3.0459708542969364,-0.471476648351972,-0.664061673412729,-0.3956516265185736,1.8686378297720425,0.04568305057423946,0.8170649925871301,-0.3768005767007224,-0.5479853796195989,1.0278684187598215,-0.7817584262207112,0.08145780404230812,0.34515985407120203,-0.3956516265185736,-0.45245684076640463,0.15256614703595497,-1.1039468355518776,-0.11716687434726772,0.06358895367080376,-0.3956516265185736,-0.7817584262207112,-0.35799118461648044,0.18790247626968237,0.04568305057423946,-0.026314622385095934,0.5674169318211052,0.2756186567217988,-0.0807106708667228,-0.283166031185393,0.7676975668159858,-0.283166031185393,0.6011152406986369,-0.11716687434726772,5.214962353364934,0.7676975668159858,1.5113424450941435,0.11708504290317308
| 2,812
|
Response to endoplasmic reticulum stress
| 19
| 73
| 2.823504
| 0.00475
|
O75955,Q7Z2K6,Q9BUN8,P16615,Q96A33,O95831,Q9Y4P3,Q8TCT9,Q96HY6,P27824,Q9H3N1,Q4ZIN3,P57088,Q9UBU6,P54578,P51572,Q9UM00,O76024,P46379
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
259,6,136,144,157,158,298,49,309,310,190,74,203,210,81,215,226,227,105
|
1814,1632,577,343,636,259,227,2390,588,1488,2000,158,903,1399,1400,529,1585,928,144,639,1586,2488,310,846,1407,105,215,81,932,906,203,2613,1548,1205,1125,1936,1894,2170,2440,936,2219,74,2174,731,1870,6,2702,1295,1762,49,1139,983,833,157,710,2450,887,309,1468,2139,583,136,987,190,1105,2386,210,226,1577,1808,2069,298,900
|
-0.30181086948961583,-0.22747447582986668,0.3624587383041505,0.7014420888364408,0.2930561203226198,0.9796636734407315,1.1235025176038205,-0.6251920440620977,0.34515985407120203,-0.17214318056581754,-0.3956516265185736,1.5567809266545096,0.09928977608158417,-0.13545318694325917,-0.13545318694325917,0.4141504853427531,-0.2089909446401189,0.08145780404230812,1.6768478836617977,0.2930561203226198,-0.2089909446401189,-0.7227042705874989,0.800639796258553,0.13484377635600422,-0.13545318694325917,2.1277249347323828,1.1709381402052799,2.4622256691784745,0.08145780404230812,0.09928977608158417,1.2337969500687216,-0.8811147225178695,-0.1905472446215371,-0.044408450650093925,-0.008258738440055532,-0.35799118461648044,-0.33922324092093464,-0.471476648351972,-0.664061673412729,0.08145780404230812,-0.5096446720406466,2.611604127146138,-0.471476648351972,0.22309537077734548,-0.3204965379073243,5.006748745407826,-1.1039468355518776,-0.0807106708667228,-0.2645618200989318,3.097288135737863,-0.008258738440055532,0.06358895367080376,0.15256614703595497,1.571876537624149,0.24063844353304098,-0.664061673412729,0.11708504290317308,0.8170649925871301,-0.15377855875444413,-0.45245684076640463,0.3624587383041505,1.7510917082093325,0.06358895367080376,1.3427506872987998,0.009759382165723819,-0.6058241514720926,1.2024227010441528,1.1393423790368928,-0.1905472446215371,-0.283166031185393,-0.41454454507068694,0.8498241944386672,0.11708504290317308
| 2,812
|
Alcohol binding
| 7
| 17
| 2.820221
| 0.004799
|
O95772,P30536,P45880,Q9BZF3,P21796,O15118,Q14108
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
11,14,17,117,23,56,62
|
2687,56,1234,636,588,11,1082,23,551,1494,14,17,2509,62,221,349,117
|
-1.062986143976836,2.916446962695746,-0.06254040557376016,0.2930561203226198,0.34515985407120203,4.707778885717138,0.009759382165723819,4.127427393456283,0.3969539001942955,-0.17214318056581754,4.433024287479104,4.287071828555498,-0.7423429355985278,2.7453620538410717,1.1551542156307362,0.7014420888364408,1.8977894929892263
| 2,812
|
Biological oxidations
| 7
| 42
| 2.815932
| 0.004864
|
Q16850,P16435,P07099,Q8TB61,Q9H2H9,P21964,O43169
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
42,108,13,79,239,149,22
|
1529,635,22,1682,956,669,2504,1438,1345,1636,433,13,1083,2156,637,1402,108,1689,149,1443,929,2289,1541,1972,1363,773,414,1167,42,878,1375,79,1521,1763,1141,1716,239,254,2708,1145,1029,953
|
-0.1905472446215371,0.2930561203226198,4.127427393456283,-0.2459980349044931,0.06358895367080376,0.2581461514602102,-0.7423429355985278,-0.15377855875444413,-0.11716687434726772,-0.22747447582986668,0.5505191412386632,4.433024287479104,0.009759382165723819,-0.471476648351972,0.2930561203226198,-0.13545318694325917,2.0850480342379543,-0.2459980349044931,1.6469797626441487,-0.15377855875444413,0.08145780404230812,-0.5479853796195989,-0.1905472446215371,-0.3768005767007224,-0.11716687434726772,0.18790247626968237,0.5842822509907212,-0.026314622385095934,3.2495966741269706,0.11708504290317308,-0.11716687434726772,2.489563986964071,-0.17214318056581754,-0.2645618200989318,-0.008258738440055532,-0.2459980349044931,1.0758136453276277,1.0118291637604662,-1.1245031466065663,-0.008258738440055532,0.04568305057423946,0.08145780404230812
| 2,812
|
Endoplasmic reticulum
| 46
| 175
| 2.813739
| 0.004897
|
Q15800,Q9BUN8,O14681,P21964,O43169,O95197,O15269,P43307,Q8WUJ1,P84157,Q96A33,Q70UQ0,Q86XL3,Q96KA5,P37268,Q5BJF2,Q96A57,Q16850,P35790,Q9P035,Q96G23,Q8TCT9,Q9NQC3,Q8NF37,Q96HY6,P27824,Q9H3N1,Q15041,Q6UW68,Q4ZIN3,Q9BT22,Q9P2W9,P51572,Q14849,P51648,Q9UM00,O96005,Q96KC8,Q99943,Q14257,O95470,Q86UE4,Q9NZ01,O00264,Q96GC9,O15260
|
Localization
|
Protein Atlas Subcellular
|
protein_atlas_subcellular_location_all
|
129,136,266,149,22,25,151,27,155,156,157,284,32,161,38,40,169,42,290,172,47,49,51,179,309,310,190,195,328,74,209,87,215,221,91,226,99,230,103,240,113,243,115,118,122,127
|
1728,118,738,266,1632,127,151,22,994,336,432,2551,1344,636,1034,2390,588,25,2000,113,466,99,1636,504,1346,1035,1081,529,862,2333,1585,1038,1039,928,1192,639,2364,1852,1539,2432,149,2315,968,2250,845,2488,310,653,1407,604,1280,2805,1010,290,2086,38,1886,745,27,1742,2412,1501,2088,2253,2489,1162,697,533,1645,2636,215,91,906,2613,2128,2009,1454,774,870,848,2162,1243,1320,1698,1368,1932,1933,1244,2129,538,1599,1699,1860,776,1934,1506,2586,2164,2541,1019,1284,2166,156,399,2168,1702,425,2545,2170,1896,240,1556,1653,221,195,1559,1509,657,129,42,74,40,2221,941,328,571,284,243,2017,32,2643,1137,1257,179,1762,49,2475,155,1139,709,1519,157,169,451,482,710,47,122,309,161,230,497,103,2420,209,136,987,2481,190,803,51,407,1266,1071,115,172,2204,2279,2308,87,857,1181,516,226,1186
|
-0.2645618200989318,1.8832252764522284,0.2055167698607001,0.9473814090258249,-0.22747447582986668,1.780620541054555,1.617013061048013,4.127427393456283,0.04568305057423946,0.7180526668602384,0.5505191412386632,-0.7817584262207112,-0.11716687434726772,0.2930561203226198,0.027739919068620857,-0.6251920440620977,0.34515985407120203,4.092876418130871,-0.3956516265185736,1.970265053697904,0.49962950681326135,2.2124905337818173,-0.22747447582986668,0.44844242471808454,-0.11716687434726772,0.027739919068620857,0.009759382165723819,0.4141504853427531,0.11708504290317308,-0.5865005631893707,-0.2089909446401189,0.027739919068620857,0.027739919068620857,0.08145780404230812,-0.044408450650093925,0.2930561203226198,-0.6058241514720926,-0.3204965379073243,-0.1905472446215371,-0.664061673412729,1.6469797626441487,-0.5672210487658126,0.06358895367080376,-0.5287933290146903,0.13484377635600422,-0.7227042705874989,0.800639796258553,0.2756186567217988,-0.13545318694325917,0.3278265608377056,-0.0807106708667228,-5.067551247307878,0.04568305057423946,0.8498241944386672,-0.4334795450313125,3.4735930042919643,-0.33922324092093464,0.2055167698607001,4.01177866837398,-0.2645618200989318,-0.6446044732945461,-0.17214318056581754,-0.4334795450313125,-0.5287933290146903,-0.7227042705874989,-0.026314622385095934,0.24063844353304098,0.4141504853427531,-0.22747447582986668,-0.9211896151418975,1.1709381402052799,2.2685717667150977,0.09928977608158417,-0.8811147225178695,-0.45245684076640463,-0.3956516265185736,-0.15377855875444413,0.18790247626968237,0.11708504290317308,0.13484377635600422,-0.471476648351972,-0.06254040557376016,-0.0989194316256046,-0.2459980349044931,-0.11716687434726772,-0.35799118461648044,-0.35799118461648044,-0.06254040557376016,-0.45245684076640463,0.4141504853427531,-0.2089909446401189,-0.2459980349044931,-0.3204965379073243,0.18790247626968237,-0.35799118461648044,-0.17214318056581754,-0.8213597823323313,-0.471476648351972,-0.762027572092384,0.04568305057423946,-0.0807106708667228,-0.471476648351972,1.571876537624149,0.6011152406986369,-0.471476648351972,-0.2459980349044931,0.5674169318211052,-0.762027572092384,-0.471476648351972,-0.33922324092093464,1.0598605419718725,-0.1905472446215371,-0.22747447582986668,1.1551542156307362,1.3117556902397782,-0.1905472446215371,-0.17214318056581754,0.2756186567217988,1.780620541054555,3.2495966741269706,2.611604127146138,3.362250839676791,-0.5096446720406466,0.08145780404230812,0.7511802727305619,0.37972336891623004,0.8824626599674397,1.043878838847843,-0.3956516265185736,3.7881866490986087,-0.9412993245634615,-0.008258738440055532,-0.06254040557376016,1.4044221691939036,-0.2645618200989318,3.097288135737863,-0.7031113329486606,1.5869470337151412,-0.008258738440055532,0.24063844353304098,-0.17214318056581754,1.571876537624149,1.4961454123614193,0.5335887363165991,0.48260039141735633,0.24063844353304098,3.1228430207611986,1.8686378297720425,0.8170649925871301,1.541660105153763,1.1235025176038205,0.46553808003374114,2.1560667669732525,-0.6446044732945461,1.2024227010441528,1.7510917082093325,0.06358895367080376,-0.7031113329486606,1.3427506872987998,0.17025232429825055,3.071664222481722,0.6011152406986369,-0.06254040557376016,0.027739919068620857,1.970265053697904,1.4504003260418334,-0.490539185592664,-0.5287933290146903,-0.5479853796195989,2.3520616312023908,0.13484377635600422,-0.026314622385095934,0.44844242471808454,1.1393423790368928,-0.026314622385095934
| 2,812
|
Respiratory chain
| 9
| 28
| 2.810583
| 0.004945
|
Q9UDW1,O96000,P03886,O14949,Q9Y6M9,Q9P0J0,O43676,P47985,Q6DKK2
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
64,225,100,70,231,170,10,147,180
|
1679,70,651,10,1276,477,1306,587,503,1307,902,225,590,100,723,344,2084,250,1971,605,147,797,1982,180,461,170,64,231
|
-0.2459980349044931,2.665336704465738,0.2756186567217988,4.761828046714546,-0.0807106708667228,0.48260039141735633,-0.0989194316256046,0.34515985407120203,0.44844242471808454,-0.0989194316256046,0.09928977608158417,1.1393423790368928,0.34515985407120203,2.1984168906874886,0.22309537077734548,0.7014420888364408,-0.4334795450313125,1.0118291637604662,-0.3768005767007224,0.3278265608377056,1.661926099494074,0.17025232429825055,-0.3768005767007224,1.389043853750546,0.5166255731433357,1.4809227807404823,2.732071824115165,1.1235025176038205
| 2,812
|
Mitochondrial envelope
| 106
| 263
| 2.810378
| 0.004948
|
P35232,P33121,Q99595,Q9NS69,O95168,Q70HW3,O60830,Q567V2,O43676,P30536,Q8WWV3,P45880,Q9Y2R0,O43169,P21796,P14406,Q8N4H5,Q9H061,O75964,P09601,Q96A26,Q6P4A7,Q9H2D1,Q8N2A8,Q9UBX3,Q9UDW1,O75431,O14949,Q9BQT8,Q13505,O43772,O95202,Q9NZJ7,P03886,Q8WY22,O00264,Q9Y619,P22830,P23786,Q15070,Q7KZN9,Q10713,Q9Y512,P13073,P47985,Q9Y6C9,O95831,P49748,Q9Y277,Q9P0J0,Q6DKK2,P36551,O43819,Q9H3K2,O75880,Q5XKP0,O96000,Q9Y6M9,Q96IX5,Q99623,Q07820,P22695,O76031,O14925,Q9H845,P12236,Q02978,Q9NVI7,P52888,Q709F0,P52789,Q5HYI7,Q6UXV4,P54886,P40939,Q9NQZ5,Q15388,Q9HC21,O60313,P14927,Q9Y320,Q6PI78,Q5T9A4,Q9NQ50,Q8NBU5,Q6NUK1,O43615,Q8N183,P56385,P21912,Q9UJS0,Q9BYT8,Q12981,P24539,Q96BR5,P56134,Q96CU9,P04818,O00429,O95674,O75306,P05141,O15228,Q13423,Q9NRX2,Q6UX07
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
507,506,1,2,503,5,0,8,10,14,16,17,20,22,23,28,29,30,34,37,39,46,48,58,59,64,65,70,77,88,89,92,98,100,101,118,119,126,128,130,133,138,142,146,147,153,158,160,164,170,180,197,200,207,208,212,225,231,237,248,251,250,249,255,265,261,271,273,283,287,307,308,314,332,331,341,348,350,343,344,361,367,365,393,388,387,383,417,413,410,430,428,425,435,452,447,461,454,465,466,477,487,485,510,515,512
|
118,465,1679,2330,2810,255,70,485,2626,22,383,651,10,89,200,343,2406,0,691,1276,477,1392,1306,65,2533,587,2407,1033,861,208,598,34,249,528,623,503,1307,92,902,959,466,158,225,768,1636,590,100,454,487,843,1884,723,1535,1737,37,844,1156,1401,2794,864,261,1851,146,28,344,966,1922,2158,639,1238,2084,673,23,410,1443,250,126,968,128,435,2160,1971,1591,14,2252,605,506,1783,507,931,532,197,1315,331,1119,1362,17,147,972,2770,160,1122,1646,307,578,283,607,1976,332,1820,447,413,1601,2165,874,2130,1550,1207,2595,1370,975,555,1321,271,251,138,1824,425,1324,510,88,1556,130,1327,348,644,2608,797,1982,849,704,1461,2745,730,8,308,2052,365,1375,212,180,1133,387,2175,46,367,512,314,287,5,133,2547,572,1798,1169,1945,543,1902,1515,417,58,29,1137,1616,614,388,559,1565,16,101,915,830,2477,1521,39,1296,2138,452,1566,461,2323,886,1664,1024,237,834,1764,2139,2784,1,248,1224,77,685,835,1667,713,1178,1472,1767,1954,428,2234,2028,30,1104,48,207,265,760,988,785,350,2665,2768,393,1384,341,714,515,2,665,273,564,856,98,2278,1525,170,2466,59,64,763,430,859,1810,164,764,20,1841,1073,361,1387,993,1579,1271,619,1482,526,142,119,153,231
|
1.8832252764522284,0.49962950681326135,-0.2459980349044931,-0.5865005631893707,-9.143898846056251,0.995760955144229,2.665336704465738,0.46553808003374114,-0.9011281689088609,4.127427393456283,0.6179160419293773,0.2756186567217988,4.761828046714546,2.2964854074361383,1.2494429822888136,0.7014420888364408,-0.6446044732945461,5.214962353364934,0.24063844353304098,-0.0807106708667228,0.48260039141735633,-0.13545318694325917,-0.0989194316256046,2.6920877924017246,-0.762027572092384,0.34515985407120203,-0.6446044732945461,0.027739919068620857,0.11708504290317308,1.2024227010441528,0.3278265608377056,3.55930743245453,1.0118291637604662,0.4141504853427531,0.31045870212056503,0.44844242471808454,-0.0989194316256046,2.2545833119587817,0.09928977608158417,0.06358895367080376,0.49962950681326135,1.5567809266545096,1.1393423790368928,0.18790247626968237,-0.22747447582986668,0.34515985407120203,2.1984168906874886,0.5166255731433357,0.46553808003374114,0.13484377635600422,-0.33922324092093464,0.22309537077734548,-0.1905472446215371,-0.2645618200989318,3.4735930042919643,0.13484377635600422,-0.026314622385095934,-0.13545318694325917,-2.610253866866887,0.11708504290317308,0.9635371984080219,-0.3204965379073243,1.661926099494074,3.941725005389792,0.7014420888364408,0.06358895367080376,-0.35799118461648044,-0.471476648351972,0.2930561203226198,-0.06254040557376016,-0.4334795450313125,0.2581461514602102,4.127427393456283,0.5842822509907212,-0.15377855875444413,1.0118291637604662,1.8247352597370783,0.06358895367080376,1.780620541054555,0.5505191412386632,-0.471476648351972,-0.3768005767007224,-0.2089909446401189,4.433024287479104,-0.5287933290146903,0.3278265608377056,0.44844242471808454,-0.283166031185393,0.44844242471808454,0.08145780404230812,0.4141504853427531,1.280653405466914,-0.0989194316256046,0.7346320169701449,-0.008258738440055532,-0.11716687434726772,4.287071828555498,1.661926099494074,0.06358895367080376,-1.6338631244210937,1.541660105153763,-0.008258738440055532,-0.22747447582986668,0.8170649925871301,0.3624587383041505,0.8824626599674397,0.3278265608377056,-0.3768005767007224,0.7346320169701449,-0.30181086948961583,0.5335887363165991,0.5842822509907212,-0.2089909446401189,-0.471476648351972,0.11708504290317308,-0.45245684076640463,-0.1905472446215371,-0.044408450650093925,-0.8412307870350623,-0.11716687434726772,0.06358895367080376,0.3969539001942955,-0.0989194316256046,0.9311961834886229,1.0118291637604662,1.7362913212685769,-0.30181086948961583,0.5674169318211052,-0.0989194316256046,0.44844242471808454,2.3381987787788923,-0.1905472446215371,1.7658680852573057,-0.0989194316256046,0.7014420888364408,0.2930561203226198,-0.8611490148593872,0.17025232429825055,-0.3768005767007224,0.13484377635600422,0.24063844353304098,-0.15377855875444413,-1.3118414208295384,0.22309537077734548,4.900998556422755,0.8170649925871301,-0.41454454507068694,0.6514216381177684,-0.11716687434726772,1.186694264872841,1.389043853750546,-0.008258738440055532,0.6179160419293773,-0.471476648351972,3.1483293001683137,0.6514216381177684,0.44844242471808454,0.7841840310190734,0.8661584558062926,5.017262595389153,1.7510917082093325,-0.762027572092384,0.37972336891623004,-0.283166031185393,-0.026314622385095934,-0.35799118461648044,0.4141504853427531,-0.33922324092093464,-0.17214318056581754,0.5842822509907212,2.8772408406430023,3.882958953414374,-0.008258738440055532,-0.2089909446401189,0.3278265608377056,0.6179160419293773,0.3969539001942955,-0.1905472446215371,4.309667504674183,2.170205082415253,0.09928977608158417,0.15256614703595497,-0.7031113329486606,-0.17214318056581754,3.448961903318223,-0.0807106708667228,-0.45245684076640463,0.5335887363165991,-0.1905472446215371,0.5166255731433357,-0.5672210487658126,0.11708504290317308,-0.22747447582986668,0.04568305057423946,1.0917382653656786,0.15256614703595497,-0.2645618200989318,-0.45245684076640463,-1.969120355953321,5.214962353364934,1.0278684187598215,-0.044408450650093925,2.5440011741485096,0.2581461514602102,0.15256614703595497,-0.22747447582986668,0.24063844353304098,-0.026314622385095934,-0.15377855875444413,-0.2645618200989318,-0.35799118461648044,0.5674169318211052,-0.5096446720406466,-0.3956516265185736,3.8356886250962248,0.009759382165723819,3.110074180270112,1.218123559434321,0.9635371984080219,0.2055167698607001,0.06358895367080376,0.18790247626968237,0.7014420888364408,-0.9816645976999411,-1.6119966512074293,0.6179160419293773,-0.11716687434726772,0.7180526668602384,0.24063844353304098,0.44844242471808454,5.214962353364934,0.2756186567217988,0.9311961834886229,0.3969539001942955,0.13484377635600422,2.226542769012561,-0.5287933290146903,-0.17214318056581754,1.4809227807404823,-0.6835638805894443,2.8641358146662417,2.732071824115165,0.2055167698607001,0.5674169318211052,0.13484377635600422,-0.283166031185393,1.5265139768993863,0.2055167698607001,4.150393709731816,-0.30181086948961583,0.027739919068620857,0.6681267102911925,-0.11716687434726772,0.06358895367080376,-0.1905472446215371,-0.06254040557376016,0.3278265608377056,-0.15377855875444413,0.4313132764939044,1.721466835279003,1.8832252764522284,1.617013061048013,1.1235025176038205
| 2,812
|
Sphingolipid metabolism
| 12
| 22
| 2.805329
| 0.005027
|
P16278,Q9NZJ7,P07602,Q06136,Q96G23,O95470,Q13510,O43681,P04062,P10619,O15269,P51648
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
256,98,132,9,47,113,85,182,55,245,151,91
|
151,717,182,2000,113,55,2124,2680,132,2332,245,256,270,2409,91,9,85,47,2420,2527,98,2204
|
1.617013061048013,0.22309537077734548,1.373639236931527,-0.3956516265185736,1.970265053697904,2.9684696908889308,-0.45245684076640463,-1.0425811965372063,1.7510917082093325,-0.5865005631893707,1.0278684187598215,0.995760955144229,0.9311961834886229,-0.6446044732945461,2.2685717667150977,4.772602732969393,2.393526363136978,3.1228430207611986,-0.6446044732945461,-0.7423429355985278,2.226542769012561,-0.490539185592664
| 2,812
|
Lysosomal lumen
| 16
| 33
| 2.791124
| 0.005253
|
Q9UMR5,P16278,Q9NZJ7,P10619,P07602,P08236,Q8NHP8,P17900,O14773,Q13510,O43681,P04062,P54802,P10253,Q14108,P50897
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
395,256,98,245,132,354,198,270,148,85,182,55,152,214,62,95
|
1678,2330,148,182,55,1584,2124,2680,132,2332,1349,1155,354,214,245,741,1850,2667,256,270,422,1120,95,152,2509,85,62,2643,1257,198,1334,98,395
|
-0.2459980349044931,-0.5865005631893707,1.6469797626441487,1.373639236931527,2.9684696908889308,-0.2089909446401189,-0.45245684076640463,-1.0425811965372063,1.7510917082093325,-0.5865005631893707,-0.11716687434726772,-0.026314622385095934,0.6848001484363205,1.1709381402052799,1.0278684187598215,0.2055167698607001,-0.3204965379073243,-1.0019206995296568,0.995760955144229,0.9311961834886229,0.5674169318211052,-0.008258738440055532,2.226542769012561,1.617013061048013,-0.7423429355985278,2.393526363136978,2.7453620538410717,-0.9412993245634615,-0.06254040557376016,1.2650617647579185,-0.0989194316256046,2.226542769012561,0.6179160419293773
| 2,812
|
Alzheimers disease and mirna effects
| 22
| 73
| 2.787039
| 0.005319
|
P12236,P60900,P16615,P45880,P21796,O95197,P28074,Q9Y277,P49327,O00487,Q9NQC3,Q9UJX6,P28072,P49720,Q92542,Q02750,Q96IX5,P20618,P05141,Q96GC9,P31751,Q08752
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
261,263,144,17,23,25,530,164,412,547,51,463,205,469,222,360,237,488,487,122,373,509
|
1272,547,1530,954,860,25,1310,487,1400,1921,1311,864,261,693,144,1922,724,1586,1195,488,23,743,1590,969,1115,641,1159,205,530,2085,1591,373,1046,1925,971,1119,815,17,1013,1643,412,469,553,2006,263,871,702,1205,2413,872,1209,360,1285,2722,1457,509,2011,1250,1287,1981,222,122,237,888,1298,2304,1989,1766,1470,51,463,897,164
|
-0.0807106708667228,0.3969539001942955,-0.1905472446215371,0.06358895367080376,0.11708504290317308,4.092876418130871,-0.0989194316256046,0.46553808003374114,-0.13545318694325917,-0.35799118461648044,-0.0989194316256046,0.11708504290317308,0.9635371984080219,0.24063844353304098,1.6768478836617977,-0.35799118461648044,0.22309537077734548,-0.2089909446401189,-0.044408450650093925,0.46553808003374114,4.127427393456283,0.2055167698607001,-0.2089909446401189,0.06358895367080376,-0.008258738440055532,0.2930561203226198,-0.026314622385095934,1.218123559434321,0.4141504853427531,-0.4334795450313125,-0.2089909446401189,0.6346847947097649,0.027739919068620857,-0.35799118461648044,0.06358895367080376,-0.008258738440055532,0.15256614703595497,4.287071828555498,0.04568305057423946,-0.22747447582986668,0.5842822509907212,0.49962950681326135,0.3969539001942955,-0.3956516265185736,0.9635371984080219,0.11708504290317308,0.24063844353304098,-0.044408450650093925,-0.6446044732945461,0.11708504290317308,-0.044408450650093925,0.6681267102911925,-0.0807106708667228,-1.1864793952065424,-0.15377855875444413,0.44844242471808454,-0.3956516265185736,-0.06254040557376016,-0.0807106708667228,-0.3768005767007224,1.1551542156307362,1.8686378297720425,1.0917382653656786,0.11708504290317308,-0.0807106708667228,-0.5479853796195989,-0.3768005767007224,-0.2645618200989318,-0.15377855875444413,3.071664222481722,0.5166255731433357,0.11708504290317308,1.5265139768993863
| 2,812
|
Outer mitochondrial membrane protein complex
| 8
| 16
| 2.762017
| 0.005745
|
O75431,Q9NS69,Q9Y512,Q5XKP0,Q5HYI7,Q13505,Q8N4H5,Q6UXV4
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
65,2,142,212,308,88,29,314
|
65,528,768,1315,88,348,849,308,212,314,1798,29,2,665,564,142
|
2.6920877924017246,0.4141504853427531,0.18790247626968237,-0.0989194316256046,2.3381987787788923,0.7014420888364408,0.13484377635600422,0.8170649925871301,1.186694264872841,0.7841840310190734,-0.283166031185393,3.882958953414374,5.214962353364934,0.2756186567217988,0.3969539001942955,1.721466835279003
| 2,812
|
Protein transmembrane transport
| 10
| 21
| 2.758709
| 0.005803
|
O60830,Q99595,Q9NS69,O75381,Q07820,Q15388,P31751,Q15629,O95831,O14925
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
0,1,2,145,251,348,373,124,158,255
|
255,383,0,145,528,158,768,1401,373,470,2613,1017,870,251,348,124,704,1,785,2,516
|
0.995760955144229,0.6179160419293773,5.214962353364934,1.661926099494074,0.4141504853427531,1.5567809266545096,0.18790247626968237,-0.13545318694325917,0.6346847947097649,0.49962950681326135,-0.8811147225178695,0.04568305057423946,0.11708504290317308,1.0118291637604662,0.7014420888364408,1.8540270682769622,0.24063844353304098,5.214962353364934,0.18790247626968237,5.214962353364934,0.44844242471808454
| 2,812
|
Membrane lipid biosynthetic process
| 9
| 20
| 2.748026
| 0.005996
|
Q99805,Q8NBX0,Q06136,Q9P035,Q96G23,O95470,Q13510,P04062,O15269
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
323,134,9,172,47,113,85,55,151
|
151,717,336,1234,113,55,2409,9,1166,85,730,134,756,1465,47,617,323,2527,172,2204
|
1.617013061048013,0.22309537077734548,0.7180526668602384,-0.06254040557376016,1.970265053697904,2.9684696908889308,-0.6446044732945461,4.772602732969393,-0.026314622385095934,2.393526363136978,0.22309537077734548,1.7510917082093325,0.2055167698607001,-0.15377855875444413,3.1228430207611986,0.3278265608377056,0.7676975668159858,-0.7423429355985278,1.4504003260418334,-0.490539185592664
| 2,812
|
Corneal opacity
| 16
| 42
| 2.744949
| 0.006052
|
P16278,Q9Y4P3,Q92889,P08236,Q06136,P54886,O75381,Q9NVI7,P02545,Q13510,P04062,P10619,O75844,P51648,O95202,P40855
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
256,298,322,354,9,332,145,273,371,85,55,245,57,91,92,345
|
2152,2640,995,1881,2532,145,57,790,92,2123,371,55,1584,2124,354,1965,245,256,550,1042,2754,1784,345,818,91,492,332,2338,1603,9,1458,85,1288,1096,1707,387,322,273,857,2639,1030,298
|
-0.471476648351972,-0.9412993245634615,0.04568305057423946,-0.33922324092093464,-0.762027572092384,1.661926099494074,2.8772408406430023,0.17025232429825055,2.2545833119587817,-0.45245684076640463,0.6346847947097649,2.9684696908889308,-0.2089909446401189,-0.45245684076640463,0.6848001484363205,-0.3768005767007224,1.0278684187598215,0.995760955144229,0.3969539001942955,0.027739919068620857,-1.4391379895738585,-0.283166031185393,0.7014420888364408,0.15256614703595497,2.2685717667150977,0.46553808003374114,0.7346320169701449,-0.5865005631893707,-0.2089909446401189,4.772602732969393,-0.15377855875444413,2.393526363136978,-0.0807106708667228,0.009759382165723819,-0.2459980349044931,0.6179160419293773,0.7676975668159858,0.9311961834886229,0.13484377635600422,-0.9211896151418975,0.04568305057423946,0.8498241944386672
| 2,812
|
Cellular response to biotic stimulus
| 11
| 32
| 2.736282
| 0.006214
|
Q8IXJ6,Q8WTV0,Q9Y263,Q9UM00,O76024,P30536,P08670,Q86UE4,Q9NUQ9,O75844,Q96A33
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
131,67,325,226,227,14,238,243,312,57,157
|
788,57,227,1399,238,1351,385,638,1922,1406,2085,14,792,1827,540,850,2099,1254,2134,1563,243,131,2019,67,1800,157,2353,1384,312,2033,226,325
|
0.17025232429825055,2.8772408406430023,1.1235025176038205,-0.13545318694325917,1.0758136453276277,-0.11716687434726772,0.6179160419293773,0.2930561203226198,-0.35799118461648044,-0.13545318694325917,-0.4334795450313125,4.433024287479104,0.17025232429825055,-0.30181086948961583,0.4141504853427531,0.13484377635600422,-0.4334795450313125,-0.06254040557376016,-0.45245684076640463,-0.1905472446215371,1.043878838847843,1.7658680852573057,-0.3956516265185736,2.678721796351966,-0.283166031185393,1.571876537624149,-0.5865005631893707,-0.11716687434726772,0.800639796258553,-0.3956516265185736,1.1393423790368928,0.7676975668159858
| 2,812
|
Tetrapyrrole metabolic process
| 6
| 20
| 2.734778
| 0.006242
|
P09601,Q7KZN9,P30536,O00264,P22830,P30519
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
37,133,14,118,126,31
|
118,691,1112,37,126,1044,31,14,411,197,1122,472,2445,133,1716,855,802,2466,949,394
|
1.8832252764522284,0.24063844353304098,-0.008258738440055532,3.4735930042919643,1.8247352597370783,0.027739919068620857,3.80008400175991,4.433024287479104,0.5842822509907212,1.280653405466914,-0.008258738440055532,0.49962950681326135,-0.664061673412729,1.7510917082093325,-0.2459980349044931,0.13484377635600422,0.17025232429825055,-0.6835638805894443,0.08145780404230812,0.6179160419293773
| 2,812
|
Lytic vacuole organization
| 8
| 20
| 2.728194
| 0.006368
|
Q8NHS3,Q8N511,O14773,O75503,P04062,P54802,Q14108,P50897
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
41,12,148,213,55,152,62,95
|
2484,148,213,739,55,2332,214,741,1119,95,1856,152,1367,62,2716,12,41,2178,1988,1809
|
-0.7227042705874989,1.6469797626441487,1.1709381402052799,0.2055167698607001,2.9684696908889308,-0.5865005631893707,1.1709381402052799,0.2055167698607001,-0.008258738440055532,2.226542769012561,-0.3204965379073243,1.617013061048013,-0.11716687434726772,2.7453620538410717,-1.1657691353785238,4.466400716267569,3.349799142139882,-0.471476648351972,-0.3768005767007224,-0.283166031185393
| 2,812
|
Organic anion transmembrane transporter activity
| 18
| 28
| 2.72746
| 0.006382
|
P33527,Q14728,Q9UJS0,P12236,Q6NUK1,P30825,Q01650,Q9BQT8,Q02978,Q9H2D1,Q8TB61,O43808,Q9H2H9,P05141,Q9Y619,Q9HC21,Q9UBX3,Q15758
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
411,163,430,261,387,386,520,77,271,48,79,586,239,487,119,350,59,611
|
1680,586,861,487,924,2688,864,261,386,411,607,1819,520,271,163,611,387,2054,79,834,77,48,239,760,350,59,430,119
|
-0.2459980349044931,0.34515985407120203,0.11708504290317308,0.46553808003374114,0.08145780404230812,-1.062986143976836,0.11708504290317308,0.9635371984080219,0.6179160419293773,0.5842822509907212,0.3278265608377056,-0.30181086948961583,0.4313132764939044,0.9311961834886229,1.5265139768993863,0.3278265608377056,0.6179160419293773,-0.41454454507068694,2.489563986964071,0.15256614703595497,2.5440011741485096,3.110074180270112,1.0758136453276277,0.2055167698607001,0.7014420888364408,2.8641358146662417,0.5674169318211052,1.8832252764522284
| 2,812
|
Proton transporting two sector atpase complex
| 10
| 21
| 2.722018
| 0.006488
|
P56385,Q9Y487,O75964,P61421,Q8N511,Q96IX5,Q93050,P24539,P36543,Q9Y5K8
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
413,3,34,424,12,237,53,435,313,327
|
598,34,843,694,674,435,2160,532,313,1314,972,447,413,424,1418,12,53,237,787,3,327
|
0.3278265608377056,3.55930743245453,0.13484377635600422,0.24063844353304098,0.2581461514602102,0.5505191412386632,-0.471476648351972,0.4141504853427531,0.7841840310190734,-0.0989194316256046,0.06358895367080376,0.5335887363165991,0.5842822509907212,0.5674169318211052,-0.13545318694325917,4.466400716267569,3.0459708542969364,1.0917382653656786,0.18790247626968237,5.214962353364934,0.7676975668159858
| 2,812
|
Porphyrin containing compound metabolic process
| 6
| 18
| 2.719287
| 0.006542
|
P09601,Q7KZN9,P30536,O00264,P22830,P30519
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
37,133,14,118,126,31
|
118,691,1112,37,126,1044,31,14,411,197,1122,472,2445,133,855,2466,949,394
|
1.8832252764522284,0.24063844353304098,-0.008258738440055532,3.4735930042919643,1.8247352597370783,0.027739919068620857,3.80008400175991,4.433024287479104,0.5842822509907212,1.280653405466914,-0.008258738440055532,0.49962950681326135,-0.664061673412729,1.7510917082093325,0.13484377635600422,-0.6835638805894443,0.08145780404230812,0.6179160419293773
| 2,812
|
Metallopeptidase activity
| 15
| 38
| 2.697124
| 0.006994
|
Q7L5N1,P36551,Q7Z2K6,P55786,Q9BYT8,O43847,Q10713,P42892,P09960,Q5JRX3,Q969V3,O75844,Q9NZ08,P52888,P22695
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
260,197,6,102,428,232,138,171,139,177,380,57,317,283,250
|
1078,547,1109,232,2533,57,2389,2536,139,2727,693,250,2316,197,171,2006,283,102,138,177,1020,1254,260,6,833,380,1141,1764,443,1066,428,1805,1624,918,735,317,518,526
|
0.009759382165723819,0.3969539001942955,-0.008258738440055532,1.1076345177979037,-0.762027572092384,2.8772408406430023,-0.6251920440620977,-0.762027572092384,1.721466835279003,-1.2280559205447314,0.24063844353304098,1.0118291637604662,-0.5672210487658126,1.280653405466914,1.4656744516817248,-0.3956516265185736,0.8824626599674397,2.1560667669732525,1.7362913212685769,1.4197742854475608,0.04568305057423946,-0.06254040557376016,0.9796636734407315,5.006748745407826,0.15256614703595497,0.6346847947097649,-0.008258738440055532,-0.2645618200989318,0.5505191412386632,0.027739919068620857,0.5674169318211052,-0.283166031185393,-0.2089909446401189,0.09928977608158417,0.22309537077734548,0.7841840310190734,0.44844242471808454,0.4313132764939044
| 2,812
|
Transition metal ion homeostasis
| 6
| 22
| 2.696215
| 0.007013
|
Q9Y487,P09601,O43819,Q8N511,Q8NEW0,P30519
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
3,37,200,12,125,31
|
2484,2284,200,2551,691,208,767,2536,1920,37,1043,31,867,1314,424,2294,1418,12,125,855,1069,3
|
-0.7227042705874989,-0.5479853796195989,1.2494429822888136,-0.7817584262207112,0.24063844353304098,1.2024227010441528,0.18790247626968237,-0.762027572092384,-0.35799118461648044,3.4735930042919643,0.027739919068620857,3.80008400175991,0.11708504290317308,-0.0989194316256046,0.5674169318211052,-0.5479853796195989,-0.13545318694325917,4.466400716267569,1.8540270682769622,0.13484377635600422,0.027739919068620857,5.214962353364934
| 2,812
|
Abnormal macular morphology
| 6
| 24
| 2.693034
| 0.007081
|
Q8NHS3,P04439,Q13510,P04062,P51648,P50897
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
41,204,85,55,91,95
|
1234,55,2507,204,550,1238,1042,1116,2194,1925,1088,1596,95,91,1975,2437,85,878,1254,41,1516,1712,1669,226
|
-0.06254040557376016,2.9684696908889308,-0.7423429355985278,1.218123559434321,0.3969539001942955,-0.06254040557376016,0.027739919068620857,-0.008258738440055532,-0.490539185592664,-0.35799118461648044,0.009759382165723819,-0.2089909446401189,2.226542769012561,2.2685717667150977,-0.3768005767007224,-0.664061673412729,2.393526363136978,0.11708504290317308,-0.06254040557376016,3.349799142139882,-0.17214318056581754,-0.2459980349044931,-0.22747447582986668,1.1393423790368928
| 2,812
|
Proton transmembrane transport
| 19
| 41
| 2.688888
| 0.007169
|
Q7KZN9,P13073,P47985,P36542,P56385,O75964,P61421,P24539,P05023,P36543,Q9UDW1,P56134,P00403,O75947,Q96ES6,P05141,P51790,Q13423,Q99623
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
133,146,147,532,413,34,424,435,184,313,64,447,590,598,112,487,242,510,248
|
1679,1680,1846,1276,598,34,590,184,487,843,723,1156,864,146,673,694,674,435,2160,1591,605,532,313,1314,147,972,242,447,413,424,975,510,133,2601,112,2139,248,64,1477,787,859
|
-0.2459980349044931,-0.2459980349044931,-0.3204965379073243,-0.0807106708667228,0.3278265608377056,3.55930743245453,0.34515985407120203,1.3582082159271402,0.46553808003374114,0.13484377635600422,0.22309537077734548,-0.026314622385095934,0.11708504290317308,1.661926099494074,0.2581461514602102,0.24063844353304098,0.2581461514602102,0.5505191412386632,-0.471476648351972,-0.2089909446401189,0.3278265608377056,0.4141504853427531,0.7841840310190734,-0.0989194316256046,1.661926099494074,0.06358895367080376,1.043878838847843,0.5335887363165991,0.5842822509907212,0.5674169318211052,0.06358895367080376,0.44844242471808454,1.7510917082093325,-0.8412307870350623,1.984691640902663,-0.45245684076640463,1.0278684187598215,2.732071824115165,-0.15377855875444413,0.18790247626968237,0.13484377635600422
| 2,812
|
Response to oxygen levels
| 12
| 56
| 2.684414
| 0.007266
|
Q9Y487,Q8IXJ6,Q9Y4P3,P09601,Q6RW13,Q96A26,P55786,Q8N511,Q15120,Q99623,O95831,P30519
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
3,131,298,37,229,39,102,12,83,248,158,31
|
1390,2549,1846,477,1999,1488,158,1489,371,2536,1920,1399,467,1534,529,37,2688,928,1922,2584,1042,1924,31,1006,1641,1314,1119,1854,412,2435,307,102,424,1700,1746,1166,83,1418,2660,1796,229,131,12,1464,2104,757,39,2450,887,248,1668,1384,1577,3,2069,298
|
-0.13545318694325917,-0.7817584262207112,-0.3204965379073243,0.48260039141735633,-0.3956516265185736,-0.17214318056581754,1.5567809266545096,-0.17214318056581754,0.6346847947097649,-0.762027572092384,-0.35799118461648044,-0.13545318694325917,0.49962950681326135,-0.1905472446215371,0.4141504853427531,3.4735930042919643,-1.062986143976836,0.08145780404230812,-0.35799118461648044,-0.8213597823323313,0.027739919068620857,-0.35799118461648044,3.80008400175991,0.04568305057423946,-0.22747447582986668,-0.0989194316256046,-0.008258738440055532,-0.3204965379073243,0.5842822509907212,-0.664061673412729,0.8170649925871301,2.1560667669732525,0.5674169318211052,-0.2459980349044931,-0.2645618200989318,-0.026314622385095934,2.448526345052684,-0.13545318694325917,-0.9816645976999411,-0.283166031185393,1.1235025176038205,1.7658680852573057,4.466400716267569,-0.15377855875444413,-0.4334795450313125,0.2055167698607001,3.448961903318223,-0.664061673412729,0.11708504290317308,1.0278684187598215,-0.22747447582986668,-0.11716687434726772,-0.1905472446215371,5.214962353364934,-0.41454454507068694,0.8498241944386672
| 2,812
|
Mitochondrial protein containing complex
| 31
| 139
| 2.683007
| 0.007296
|
O60830,Q99595,Q9NS69,P12236,Q567V2,O43676,Q9Y512,P13073,P47985,P21796,P14406,Q8N4H5,O75964,Q9P0J0,Q5HYI7,Q6UXV4,Q9UDW1,O75431,O14949,P40939,Q5XKP0,Q15388,Q13505,O96000,P03886,Q9Y6M9,Q96IX5,Q99623,P22695,O76031,O14925
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
0,1,2,261,8,10,142,146,147,23,28,29,34,170,308,314,64,65,70,331,212,348,88,225,100,231,237,248,250,249,255
|
1916,1679,255,70,651,10,1151,0,1276,477,1306,65,587,598,34,249,528,503,1307,902,225,768,590,100,487,843,1817,723,1535,962,844,1780,1156,1491,2583,864,261,146,28,344,966,2084,673,23,410,250,435,2160,1971,1591,2252,605,507,532,1315,331,147,972,2770,1596,1646,578,2008,1820,447,413,1601,874,2130,1550,1207,2595,1370,1324,88,348,797,1982,849,704,1461,730,8,308,2052,212,2175,314,1761,2547,572,1798,543,1660,1902,29,1616,1565,915,1296,461,2323,886,615,237,2808,1,248,1989,1224,685,1178,1472,1767,2234,988,785,2563,2665,2768,393,515,2,665,564,856,2278,170,64,1810,764,1841,1073,993,1579,1271,526,142,231
|
-0.35799118461648044,-0.2459980349044931,0.995760955144229,2.665336704465738,0.2756186567217988,4.761828046714546,-0.026314622385095934,5.214962353364934,-0.0807106708667228,0.48260039141735633,-0.0989194316256046,2.6920877924017246,0.34515985407120203,0.3278265608377056,3.55930743245453,1.0118291637604662,0.4141504853427531,0.44844242471808454,-0.0989194316256046,0.09928977608158417,1.1393423790368928,0.18790247626968237,0.34515985407120203,2.1984168906874886,0.46553808003374114,0.13484377635600422,-0.30181086948961583,0.22309537077734548,-0.1905472446215371,0.06358895367080376,0.13484377635600422,-0.283166031185393,-0.026314622385095934,-0.17214318056581754,-0.8213597823323313,0.11708504290317308,0.9635371984080219,1.661926099494074,3.941725005389792,0.7014420888364408,0.06358895367080376,-0.4334795450313125,0.2581461514602102,4.127427393456283,0.5842822509907212,1.0118291637604662,0.5505191412386632,-0.471476648351972,-0.3768005767007224,-0.2089909446401189,-0.5287933290146903,0.3278265608377056,0.44844242471808454,0.4141504853427531,-0.0989194316256046,0.7346320169701449,1.661926099494074,0.06358895367080376,-1.6338631244210937,-0.2089909446401189,-0.22747447582986668,0.3624587383041505,-0.3956516265185736,-0.30181086948961583,0.5335887363165991,0.5842822509907212,-0.2089909446401189,0.11708504290317308,-0.45245684076640463,-0.1905472446215371,-0.044408450650093925,-0.8412307870350623,-0.11716687434726772,-0.0989194316256046,2.3381987787788923,0.7014420888364408,0.17025232429825055,-0.3768005767007224,0.13484377635600422,0.24063844353304098,-0.15377855875444413,0.22309537077734548,4.900998556422755,0.8170649925871301,-0.41454454507068694,1.186694264872841,-0.471476648351972,0.7841840310190734,-0.2645618200989318,-0.762027572092384,0.37972336891623004,-0.283166031185393,0.4141504853427531,-0.22747447582986668,-0.33922324092093464,3.882958953414374,-0.2089909446401189,-0.1905472446215371,0.09928977608158417,-0.0807106708667228,0.5166255731433357,-0.5672210487658126,0.11708504290317308,0.3278265608377056,1.0917382653656786,-8.22592862627878,5.214962353364934,1.0278684187598215,-0.3768005767007224,-0.044408450650093925,0.2581461514602102,-0.026314622385095934,-0.15377855875444413,-0.2645618200989318,-0.5096446720406466,0.06358895367080376,0.18790247626968237,-0.7817584262207112,-0.9816645976999411,-1.6119966512074293,0.6179160419293773,0.44844242471808454,5.214962353364934,0.2756186567217988,0.3969539001942955,0.13484377635600422,-0.5287933290146903,1.4809227807404823,2.732071824115165,-0.283166031185393,0.2055167698607001,-0.30181086948961583,0.027739919068620857,0.06358895367080376,-0.1905472446215371,-0.06254040557376016,0.4313132764939044,1.721466835279003,1.1235025176038205
| 2,812
|
Cytochrome complex
| 7
| 17
| 2.679693
| 0.007369
|
Q9UDW1,Q7KZN9,O14949,P13073,P47985,P14406,P22695
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
64,133,70,146,147,28,250
|
1679,70,590,723,844,1156,146,28,344,966,673,250,605,147,133,64,1810
|
-0.2459980349044931,2.665336704465738,0.34515985407120203,0.22309537077734548,0.13484377635600422,-0.026314622385095934,1.661926099494074,3.941725005389792,0.7014420888364408,0.06358895367080376,0.2581461514602102,1.0118291637604662,0.3278265608377056,1.661926099494074,1.7510917082093325,2.732071824115165,-0.283166031185393
| 2,812
|
Abnormality of hepatobiliary system physiology
| 19
| 64
| 2.674814
| 0.007477
|
P23786,Q10713,Q8N511,O75381,P55263,Q96A33,P04062,O15118,O43819,P01889,Q9BT22,Q5XKP0,Q13510,O43772,P03886,Q9Y619,Q96C23,P22695,P22830
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
128,138,12,145,18,157,55,56,200,201,209,212,85,89,100,119,252,250,126
|
2776,56,89,200,2531,477,145,597,2582,201,100,55,1347,600,723,962,2794,1404,250,126,128,904,2796,552,1886,345,331,1694,2087,472,1820,18,1977,2614,377,138,85,1653,426,1755,1168,438,212,913,1761,2057,12,1762,1565,157,252,2303,1223,209,265,1227,948,2183,1672,1810,1073,1482,2387,119
|
-1.7219202513137202,2.916446962695746,2.2964854074361383,1.2494429822888136,-0.762027572092384,0.48260039141735633,1.661926099494074,0.3278265608377056,-0.8213597823323313,1.2494429822888136,2.1984168906874886,2.9684696908889308,-0.11716687434726772,0.3278265608377056,0.22309537077734548,0.06358895367080376,-2.610253866866887,-0.13545318694325917,1.0118291637604662,1.8247352597370783,1.780620541054555,0.09928977608158417,-2.8360346312201887,0.3969539001942955,-0.33922324092093464,0.7014420888364408,0.7346320169701449,-0.2459980349044931,-0.4334795450313125,0.49962950681326135,-0.30181086948961583,4.287071828555498,-0.3768005767007224,-0.8811147225178695,0.6346847947097649,1.7362913212685769,2.393526363136978,-0.22747447582986668,0.5674169318211052,-0.2645618200989318,-0.026314622385095934,0.5505191412386632,1.186694264872841,0.09928977608158417,-0.2645618200989318,-0.41454454507068694,4.466400716267569,-0.2645618200989318,-0.1905472446215371,1.571876537624149,1.0118291637604662,-0.5479853796195989,-0.044408450650093925,1.2024227010441528,0.9635371984080219,-0.044408450650093925,0.08145780404230812,-0.471476648351972,-0.22747447582986668,-0.283166031185393,0.027739919068620857,-0.15377855875444413,-0.6058241514720926,1.8832252764522284
| 2,812
|
transmembrane signal receptor
| 6
| 8
| 2.669062
| 0.007606
|
O15173,Q99720,Q9UMX5,O00264,Q96GC9,Q8WUJ1
|
Functions
|
Panther Protein class
|
panther_protein_class
|
36,135,141,118,122,155
|
118,36,1350,185,155,122,135,141
|
1.8832252764522284,3.498161016050837,-0.11716687434726772,1.3582082159271402,1.5869470337151412,1.8686378297720425,1.7510917082093325,1.721466835279003
| 2,812
|
Transporter
| 56
| 168
| 2.668779
| 0.007613
|
Q9Y487,P20020,Q15070,Q70HW3,P12236,Q6NUK1,P30825,Q8TEX9,P17900,Q02978,P16615,Q00765,Q9Y6C9,P51809,Q9BQE5,Q9Y3B3,P56385,P33527,Q9UJS0,Q8IXU6,P61421,Q8NFH4,Q9H2D1,Q86Y82,Q93050,O43493,P24539,Q9UBX3,P05023,P63010,Q9Y5K8,Q9Y3A6,Q99805,Q9HD45,P56134,P08183,Q10567,Q9BQT8,Q8TB61,P05026,Q9P2W9,P51572,Q15388,O43772,Q9HC21,O95202,Q9UNK0,Q13596,Q9NZJ7,P52292,Q13190,Q9H2H9,Q96ES6,O43760,Q9Y619,Q8NEW0
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
3,257,130,5,261,387,386,403,270,271,144,399,153,397,26,282,413,411,430,294,424,174,48,439,53,181,435,59,184,437,327,326,323,68,447,71,321,77,79,467,87,215,348,89,350,92,351,347,98,359,233,239,112,116,119,125
|
2769,1813,2484,1079,1729,1815,2284,718,181,116,89,586,501,1305,720,1683,691,1882,861,598,1001,92,2000,923,565,768,184,467,487,843,71,924,672,926,2688,566,864,261,144,270,257,694,674,435,2160,904,846,386,411,1010,532,1117,1314,1502,817,697,470,215,397,359,1744,607,2256,2336,2092,1819,1696,1201,1697,1366,1051,2127,447,413,655,424,870,1203,437,975,1551,399,520,271,321,796,2707,2195,233,2294,347,1093,1095,130,2575,1980,2219,348,611,2661,387,2054,5,495,799,661,439,294,732,1947,125,174,2321,79,733,403,2692,1464,2104,1261,2601,800,53,2178,1567,112,2021,834,1988,1333,1952,1264,323,26,77,2519,562,759,2748,595,48,239,836,760,350,68,98,2033,2204,87,1574,1303,59,787,2602,430,351,668,1304,689,326,282,3,327,2387,119,2310,153
|
-1.6338631244210937,-0.30181086948961583,-0.7227042705874989,0.009759382165723819,-0.2645618200989318,-0.30181086948961583,-0.5479853796195989,0.22309537077734548,1.373639236931527,1.8977894929892263,2.2964854074361383,0.34515985407120203,0.44844242471808454,-0.0989194316256046,0.22309537077734548,-0.2459980349044931,0.24063844353304098,-0.33922324092093464,0.11708504290317308,0.3278265608377056,0.04568305057423946,2.2545833119587817,-0.3956516265185736,0.08145780404230812,0.37972336891623004,0.18790247626968237,1.3582082159271402,0.49962950681326135,0.46553808003374114,0.13484377635600422,2.665336704465738,0.08145780404230812,0.2581461514602102,0.08145780404230812,-1.062986143976836,0.37972336891623004,0.11708504290317308,0.9635371984080219,1.6768478836617977,0.9311961834886229,0.995760955144229,0.24063844353304098,0.2581461514602102,0.5505191412386632,-0.471476648351972,0.09928977608158417,0.13484377635600422,0.6179160419293773,0.5842822509907212,0.04568305057423946,0.4141504853427531,-0.008258738440055532,-0.0989194316256046,-0.17214318056581754,0.15256614703595497,0.24063844353304098,0.49962950681326135,1.1709381402052799,0.6011152406986369,0.6681267102911925,-0.2645618200989318,0.3278265608377056,-0.5287933290146903,-0.5865005631893707,-0.4334795450313125,-0.30181086948961583,-0.2459980349044931,-0.044408450650093925,-0.2459980349044931,-0.11716687434726772,0.027739919068620857,-0.45245684076640463,0.5335887363165991,0.5842822509907212,0.2756186567217988,0.5674169318211052,0.11708504290317308,-0.044408450650093925,0.5505191412386632,0.06358895367080376,-0.1905472446215371,0.6011152406986369,0.4313132764939044,0.9311961834886229,0.7676975668159858,0.17025232429825055,-1.1245031466065663,-0.490539185592664,1.0917382653656786,-0.5479853796195989,0.7014420888364408,0.009759382165723819,0.009759382165723819,1.7658680852573057,-0.801535746199426,-0.3768005767007224,-0.5096446720406466,0.7014420888364408,0.3278265608377056,-0.9816645976999411,0.6179160419293773,-0.41454454507068694,5.017262595389153,0.46553808003374114,0.17025232429825055,0.2756186567217988,0.5505191412386632,0.8498241944386672,0.22309537077734548,-0.35799118461648044,1.8540270682769622,1.435100304078915,-0.5672210487658126,2.489563986964071,0.22309537077734548,0.6011152406986369,-1.062986143976836,-0.15377855875444413,-0.4334795450313125,-0.06254040557376016,-0.8412307870350623,0.17025232429825055,3.0459708542969364,-0.471476648351972,-0.1905472446215371,1.984691640902663,-0.3956516265185736,0.15256614703595497,-0.3768005767007224,-0.0989194316256046,-0.35799118461648044,-0.06254040557376016,0.7676975668159858,4.069774341527857,2.5440011741485096,-0.7423429355985278,0.3969539001942955,0.2055167698607001,-1.375243635959107,0.34515985407120203,3.110074180270112,1.0758136453276277,0.15256614703595497,0.2055167698607001,0.7014420888364408,2.678721796351966,2.226542769012561,-0.3956516265185736,-0.490539185592664,2.3520616312023908,-0.1905472446215371,-0.0807106708667228,2.8641358146662417,0.18790247626968237,-0.8412307870350623,0.5674169318211052,0.7014420888364408,0.2756186567217988,-0.0807106708667228,0.2581461514602102,0.7676975668159858,0.8987369327594061,5.214962353364934,0.7676975668159858,-0.6058241514720926,1.8832252764522284,-0.5479853796195989,1.617013061048013
| 2,812
|
Alzheimers disease
| 21
| 52
| 2.656596
| 0.007893
|
O95168,O43676,P16615,P13073,P47985,P14406,P36542,P21912,P49327,P24539,Q9UDW1,O14949,P00403,O75489,Q92542,P14927,O96000,O75306,O75947,Q9Y6M9,P22695
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
503,10,144,146,147,28,532,410,412,435,64,70,590,587,222,344,225,477,598,231,250
|
1679,70,651,10,1276,477,1306,587,598,503,1307,902,225,590,1310,843,1921,723,844,1156,146,28,693,344,966,144,1922,2084,673,410,250,435,2160,1971,2085,2252,605,532,147,972,412,1209,2722,1457,1250,797,1982,222,1989,64,1477,231
|
-0.2459980349044931,2.665336704465738,0.2756186567217988,4.761828046714546,-0.0807106708667228,0.48260039141735633,-0.0989194316256046,0.34515985407120203,0.3278265608377056,0.44844242471808454,-0.0989194316256046,0.09928977608158417,1.1393423790368928,0.34515985407120203,-0.0989194316256046,0.13484377635600422,-0.35799118461648044,0.22309537077734548,0.13484377635600422,-0.026314622385095934,1.661926099494074,3.941725005389792,0.24063844353304098,0.7014420888364408,0.06358895367080376,1.6768478836617977,-0.35799118461648044,-0.4334795450313125,0.2581461514602102,0.5842822509907212,1.0118291637604662,0.5505191412386632,-0.471476648351972,-0.3768005767007224,-0.4334795450313125,-0.5287933290146903,0.3278265608377056,0.4141504853427531,1.661926099494074,0.06358895367080376,0.5842822509907212,-0.044408450650093925,-1.1864793952065424,-0.15377855875444413,-0.06254040557376016,0.17025232429825055,-0.3768005767007224,1.1551542156307362,-0.3768005767007224,2.732071824115165,-0.15377855875444413,1.1235025176038205
| 2,812
|
Inner mitochondrial membrane organization
| 12
| 17
| 2.652758
| 0.007984
|
Q6UXV4,O75431,O94826,Q9Y4W6,Q9P0J0,Q9Y512,Q9H3K2,Q5XKP0,Q5HYI7,Q13505,O95202,O60313
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
314,65,528,526,170,142,207,212,308,88,92,343
|
343,65,528,92,1315,88,849,730,308,212,314,207,665,564,170,526,142
|
0.7014420888364408,2.6920877924017246,0.4141504853427531,2.2545833119587817,-0.0989194316256046,2.3381987787788923,0.13484377635600422,0.22309537077734548,0.8170649925871301,1.186694264872841,0.7841840310190734,1.218123559434321,0.2756186567217988,0.3969539001942955,1.4809227807404823,0.4313132764939044,1.721466835279003
| 2,812
|
Delusions
| 7
| 17
| 2.652182
| 0.007997
|
Q9NZJ7,P07602,P36551,P21964,O43681,P04062,Q9BQE5
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
98,132,197,149,182,55,26
|
182,55,132,1112,149,197,275,1089,1122,1894,1605,2732,26,947,98,1478,430
|
1.373639236931527,2.9684696908889308,1.7510917082093325,-0.008258738440055532,1.6469797626441487,1.280653405466914,0.9149813991987668,0.009759382165723819,-0.008258738440055532,-0.33922324092093464,-0.2089909446401189,-1.2280559205447314,4.069774341527857,0.08145780404230812,2.226542769012561,-0.15377855875444413,0.5674169318211052
| 2,812
|
Inorganic anion transmembrane transporter activity
| 7
| 14
| 2.640718
| 0.008273
|
Q9Y277,P45880,P51790,O43681,P21796,Q9C0H2,Q9UBX3
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
164,17,242,182,23,90,59
|
807,182,23,411,17,242,1051,271,522,2661,90,59,164,1340
|
0.15256614703595497,1.373639236931527,4.127427393456283,0.5842822509907212,4.287071828555498,1.043878838847843,0.027739919068620857,0.9311961834886229,0.4313132764939044,-0.9816645976999411,2.2964854074361383,2.8641358146662417,1.5265139768993863,-0.0989194316256046
| 2,812
|
Oxidoreductase activity acting on the ch ch group of donors
| 14
| 27
| 2.640375
| 0.008281
|
P49748,P21912,Q8N4Q0,Q7KZN9,Q9H845,P36551,Q14739,O15254,Q15067,Q8N8N7,Q9NZ01,Q15392,Q9H7Z7,Q709F0
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
160,410,4,133,265,197,235,107,304,339,115,150,94,287
|
107,2794,410,2251,1044,2252,197,1161,412,160,1122,472,235,1417,304,150,287,133,4,339,943,855,2027,94,265,115,857
|
2.099295657499522,-2.610253866866887,0.5842822509907212,-0.5287933290146903,0.027739919068620857,-0.5287933290146903,1.280653405466914,-0.026314622385095934,0.5842822509907212,1.541660105153763,-0.008258738440055532,0.49962950681326135,1.0917382653656786,-0.13545318694325917,0.8334597491992295,1.6469797626441487,0.8661584558062926,1.7510917082093325,5.194333871316421,0.7180526668602384,0.08145780404230812,0.13484377635600422,-0.3956516265185736,2.2545833119587817,0.9635371984080219,1.970265053697904,0.13484377635600422
| 2,812
|
Sphingolipid biosynthetic process
| 6
| 14
| 2.637099
| 0.008362
|
Q06136,Q96G23,O95470,Q13510,P04062,O15269
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
9,47,113,85,55,151
|
151,717,113,55,2409,9,1166,85,730,47,323,2527,172,2204
|
1.617013061048013,0.22309537077734548,1.970265053697904,2.9684696908889308,-0.6446044732945461,4.772602732969393,-0.026314622385095934,2.393526363136978,0.22309537077734548,3.1228430207611986,0.7676975668159858,-0.7423429355985278,1.4504003260418334,-0.490539185592664
| 2,812
|
Neuron apoptotic process
| 9
| 42
| 2.633433
| 0.008453
|
O76024,P09601,Q96A26,Q99720,Q01105,P04062,Q92542,O95831,P50897
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
227,37,39,135,86,55,222,158,95
|
808,622,227,158,55,1920,1310,1399,1490,1083,37,1885,602,1924,373,1925,1361,676,1363,412,1855,95,2435,2007,1745,1090,1209,86,251,1864,1250,2511,909,222,1465,39,2139,135,2589,714,431,2069
|
0.15256614703595497,0.31045870212056503,1.1235025176038205,1.5567809266545096,2.9684696908889308,-0.35799118461648044,-0.0989194316256046,-0.13545318694325917,-0.17214318056581754,0.009759382165723819,3.4735930042919643,-0.33922324092093464,0.3278265608377056,-0.35799118461648044,0.6346847947097649,-0.35799118461648044,-0.11716687434726772,0.2581461514602102,-0.11716687434726772,0.5842822509907212,-0.3204965379073243,2.226542769012561,-0.664061673412729,-0.3956516265185736,-0.2645618200989318,0.009759382165723819,-0.044408450650093925,2.3797253533192024,1.0118291637604662,-0.3204965379073243,-0.06254040557376016,-0.7423429355985278,0.09928977608158417,1.1551542156307362,-0.15377855875444413,3.448961903318223,-0.45245684076640463,1.7510917082093325,-0.8213597823323313,0.24063844353304098,0.5674169318211052,-0.41454454507068694
| 2,812
|
Oxidase
| 11
| 19
| 2.627463
| 0.008602
|
P49748,Q15800,P36551,Q9H845,O43819,O15254,O75880,O43169,P14406,Q709F0,O15260
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
160,129,197,265,200,107,208,22,28,287,127
|
107,127,22,200,208,1156,2794,965,28,966,673,2251,197,160,304,129,594,287,265
|
2.099295657499522,1.780620541054555,4.127427393456283,1.2494429822888136,1.2024227010441528,-0.026314622385095934,-2.610253866866887,0.06358895367080376,3.941725005389792,0.06358895367080376,0.2581461514602102,-0.5287933290146903,1.280653405466914,1.541660105153763,0.8334597491992295,1.780620541054555,0.34515985407120203,0.8661584558062926,0.9635371984080219
| 2,812
|
Oxidoreductase complex
| 16
| 53
| 2.627375
| 0.008605
|
Q9UDW1,O96000,P21912,O95168,O75306,O14949,P03886,Q9Y6M9,O43676,Q9P0J0,Q96CU9,P47985,O43169,P31350,P22695,P14927
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
64,225,410,503,477,70,100,231,10,170,461,147,22,436,250,344
|
1679,70,22,651,10,1151,1276,477,1306,587,503,1307,902,225,1533,1636,100,1884,529,1817,723,962,1780,1491,2583,1038,965,344,2084,410,250,1639,1588,1971,2252,436,605,2612,1011,1362,147,1596,1321,797,1982,1375,1098,461,170,64,1810,993,231
|
-0.2459980349044931,2.665336704465738,4.127427393456283,0.2756186567217988,4.761828046714546,-0.026314622385095934,-0.0807106708667228,0.48260039141735633,-0.0989194316256046,0.34515985407120203,0.44844242471808454,-0.0989194316256046,0.09928977608158417,1.1393423790368928,-0.1905472446215371,-0.22747447582986668,2.1984168906874886,-0.33922324092093464,0.4141504853427531,-0.30181086948961583,0.22309537077734548,0.06358895367080376,-0.283166031185393,-0.17214318056581754,-0.8213597823323313,0.027739919068620857,0.06358895367080376,0.7014420888364408,-0.4334795450313125,0.5842822509907212,1.0118291637604662,-0.22747447582986668,-0.2089909446401189,-0.3768005767007224,-0.5287933290146903,0.5505191412386632,0.3278265608377056,-0.8811147225178695,0.04568305057423946,-0.11716687434726772,1.661926099494074,-0.2089909446401189,-0.0989194316256046,0.17025232429825055,-0.3768005767007224,-0.11716687434726772,0.009759382165723819,0.5166255731433357,1.4809227807404823,2.732071824115165,-0.283166031185393,0.06358895367080376,1.1235025176038205
| 2,812
|
Protein transporter activity
| 10
| 14
| 2.621946
| 0.008743
|
O60830,Q99595,Q9NS69,Q9UGP8,Q8NBU5,Q9HD20,P49755,Q15388,Q07820,O14925
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
0,1,2,516,388,60,470,348,251,255
|
255,0,528,768,1350,470,870,251,348,388,1,60,2,516
|
0.995760955144229,5.214962353364934,0.4141504853427531,0.18790247626968237,-0.11716687434726772,0.49962950681326135,0.11708504290317308,1.0118291637604662,0.7014420888364408,0.6179160419293773,5.214962353364934,2.8378709383397114,5.214962353364934,0.44844242471808454
| 2,812
|
Nadh dehydrogenase complex assembly
| 11
| 22
| 2.619661
| 0.008802
|
O96000,Q15070,O75306,P03886,Q9H845,Q9Y6M9,O43676,Q9P0J0,Q96CU9,Q8N183,Q9H061
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
225,130,477,100,265,231,10,170,461,417,30
|
651,10,1276,477,587,503,902,225,100,1971,130,797,1982,417,461,30,265,1525,170,1810,993,231
|
0.2756186567217988,4.761828046714546,-0.0807106708667228,0.48260039141735633,0.34515985407120203,0.44844242471808454,0.09928977608158417,1.1393423790368928,2.1984168906874886,-0.3768005767007224,1.7658680852573057,0.17025232429825055,-0.3768005767007224,0.5842822509907212,0.5166255731433357,3.8356886250962248,0.9635371984080219,-0.17214318056581754,1.4809227807404823,-0.283166031185393,0.06358895367080376,1.1235025176038205
| 2,812
|
transporter
| 9
| 56
| 2.617852
| 0.008849
|
O60830,Q99595,Q15070,Q9HD45,Q567V2,Q8NFH4,Q9H2D1,Q9Y619,O43772
|
Functions
|
Panther Protein class
|
panther_protein_class
|
0,1,130,68,8,174,48,119,89
|
1435,1729,1815,2284,1150,301,383,182,89,1305,0,2247,589,2554,1117,817,2470,359,1744,2491,607,1819,1201,905,2127,655,870,520,796,1095,130,8,2661,799,732,174,733,403,2104,800,1567,616,1264,1,323,2519,759,48,1909,68,1911,2706,2602,859,2387,119
|
-0.15377855875444413,-0.2645618200989318,-0.30181086948961583,-0.5479853796195989,-0.026314622385095934,0.8334597491992295,0.6179160419293773,1.373639236931527,2.2964854074361383,-0.0989194316256046,5.214962353364934,-0.5287933290146903,0.34515985407120203,-0.7817584262207112,-0.008258738440055532,0.15256614703595497,-0.7031113329486606,0.6681267102911925,-0.2645618200989318,-0.7227042705874989,0.3278265608377056,-0.30181086948961583,-0.044408450650093925,0.09928977608158417,-0.45245684076640463,0.2756186567217988,0.11708504290317308,0.4313132764939044,0.17025232429825055,0.009759382165723819,1.7658680852573057,4.900998556422755,-0.9816645976999411,0.17025232429825055,0.22309537077734548,1.435100304078915,0.22309537077734548,0.6011152406986369,-0.4334795450313125,0.17025232429825055,-0.1905472446215371,0.3278265608377056,-0.06254040557376016,5.214962353364934,0.7676975668159858,-0.7423429355985278,0.2055167698607001,3.110074180270112,-0.33922324092093464,2.678721796351966,-0.33922324092093464,-1.1039468355518776,-0.8412307870350623,0.13484377635600422,-0.6058241514720926,1.8832252764522284
| 2,812
|
Alcohol biosynthetic process
| 10
| 33
| 2.617714
| 0.008852
|
Q15800,P37268,Q16850,P16435,Q13510,Q15392,P04062,O15269,P48449,O76054
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
129,38,42,108,85,150,55,151,154,219
|
2035,151,717,636,219,588,961,1636,2742,55,602,320,108,1041,2778,38,1854,154,519,457,2638,1166,85,1416,235,150,657,129,1168,42,2139,2383,857
|
-0.41454454507068694,1.617013061048013,0.22309537077734548,0.2930561203226198,1.1551542156307362,0.34515985407120203,0.06358895367080376,-0.22747447582986668,-1.2908152269601356,2.9684696908889308,0.3278265608377056,0.7676975668159858,2.0850480342379543,0.027739919068620857,-1.8333497016212914,3.4735930042919643,-0.3204965379073243,1.601992510014427,0.4313132764939044,0.5166255731433357,-0.9211896151418975,-0.026314622385095934,2.393526363136978,-0.13545318694325917,1.0917382653656786,1.6469797626441487,0.2756186567217988,1.780620541054555,-0.026314622385095934,3.2495966741269706,-0.45245684076640463,-0.6058241514720926,0.13484377635600422
| 2,812
|
Cutaneous photosensitivity
| 8
| 19
| 2.616075
| 0.008895
|
Q92889,P36551,P37268,P14324,Q06136,O76031,P22830,Q14108
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
322,197,38,320,9,249,126,62
|
249,842,769,2727,320,550,1042,126,1739,1116,197,38,1122,9,363,62,322,857,1528
|
1.0118291637604662,0.13484377635600422,0.18790247626968237,-1.2280559205447314,0.7676975668159858,0.3969539001942955,0.027739919068620857,1.8247352597370783,-0.2645618200989318,-0.008258738440055532,1.280653405466914,3.4735930042919643,-0.008258738440055532,4.772602732969393,0.6514216381177684,2.7453620538410717,0.7676975668159858,0.13484377635600422,-0.17214318056581754
| 2,812
|
Molecular transducer activity
| 9
| 31
| 2.61604
| 0.008896
|
Q8WTV0,O15173,Q99720,Q9BUN8,P30536,O15118,P15260,Q15629,Q14108
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
67,36,135,136,14,56,185,124,62
|
56,36,808,1081,1350,1084,2635,185,2569,14,2788,412,1055,2722,1130,825,62,124,611,570,612,1420,229,67,1518,1952,135,136,2526,2308,516
|
2.916446962695746,3.498161016050837,0.15256614703595497,0.009759382165723819,-0.11716687434726772,0.009759382165723819,-0.9211896151418975,1.3582082159271402,-0.801535746199426,4.433024287479104,-2.1771642860934013,0.5842822509907212,0.027739919068620857,-1.1864793952065424,-0.008258738440055532,0.15256614703595497,2.7453620538410717,1.8540270682769622,0.3278265608377056,0.37972336891623004,0.3278265608377056,-0.13545318694325917,1.1235025176038205,2.678721796351966,-0.17214318056581754,-0.35799118461648044,1.7510917082093325,1.7510917082093325,-0.7423429355985278,-0.5479853796195989,0.44844242471808454
| 2,812
|
Atpase coupled transmembrane transporter activity
| 10
| 18
| 2.614306
| 0.008941
|
P33527,P20020,P08183,P61421,Q9HD20,P16615,P36543,Q15388,P05023,Q9Y5K8
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
411,257,71,424,60,144,313,348,184,327
|
691,184,467,843,71,144,257,694,674,904,411,313,1314,424,348,60,787,327
|
0.24063844353304098,1.3582082159271402,0.49962950681326135,0.13484377635600422,2.665336704465738,1.6768478836617977,0.995760955144229,0.24063844353304098,0.2581461514602102,0.09928977608158417,0.5842822509907212,0.7841840310190734,-0.0989194316256046,0.5674169318211052,0.7014420888364408,2.8378709383397114,0.18790247626968237,0.7676975668159858
| 2,812
|
Monovalent inorganic cation homeostasis
| 7
| 26
| 2.603924
| 0.009216
|
Q9Y487,Q9Y5X3,Q8N511,Q93050,O75503,P05023,P50897
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
3,167,12,53,213,184,95
|
213,739,1236,184,467,843,2085,95,1856,242,1697,1051,424,777,1418,12,2104,2601,53,2178,2737,1477,787,3,167,1340
|
1.1709381402052799,0.2055167698607001,-0.06254040557376016,1.3582082159271402,0.49962950681326135,0.13484377635600422,-0.4334795450313125,2.226542769012561,-0.3204965379073243,1.043878838847843,-0.2459980349044931,0.027739919068620857,0.5674169318211052,0.18790247626968237,-0.13545318694325917,4.466400716267569,-0.4334795450313125,-0.8412307870350623,3.0459708542969364,-0.471476648351972,-1.248922783915979,-0.15377855875444413,0.18790247626968237,5.214962353364934,1.5113424450941435,-0.0989194316256046
| 2,812
|
Sphingolipid metabolism
| 7
| 9
| 2.594291
| 0.009479
|
P07602,Q06136,O95470,Q9NZ01,Q13510,P04062,O15269
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
132,9,113,115,85,55,151
|
151,717,113,55,132,270,9,85,115
|
1.617013061048013,0.22309537077734548,1.970265053697904,2.9684696908889308,1.7510917082093325,0.9311961834886229,4.772602732969393,2.393526363136978,1.970265053697904
| 2,812
|
Abnormality of the mitochondrion
| 23
| 79
| 2.590966
| 0.009571
|
P23786,Q70HW3,Q7KZN9,Q9H845,O43676,Q9BQP7,P13073,Q9Y2R0,Q8N183,P49748,P21912,Q9P0J0,Q5JPH6,Q16836,Q9UBX3,Q96CU9,P40939,O00429,O75880,O43772,O96000,P03886,Q9Y6M9
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
128,5,133,265,10,272,146,20,417,160,410,170,305,438,59,461,331,465,208,89,225,100,231
|
465,1679,10,89,1276,477,1306,587,597,208,902,225,590,100,1817,962,1780,1491,2794,864,146,965,2084,673,410,1443,128,1969,1971,531,2252,744,1011,331,2087,1642,1120,160,578,2008,1976,932,2165,975,876,1249,1374,2608,1982,438,704,798,305,2445,2053,5,133,1462,417,1565,2302,461,1664,1223,2610,1989,272,2028,265,1525,170,949,59,1957,20,993,1482,526,231
|
0.49962950681326135,-0.2459980349044931,4.761828046714546,2.2964854074361383,-0.0807106708667228,0.48260039141735633,-0.0989194316256046,0.34515985407120203,0.3278265608377056,1.2024227010441528,0.09928977608158417,1.1393423790368928,0.34515985407120203,2.1984168906874886,-0.30181086948961583,0.06358895367080376,-0.283166031185393,-0.17214318056581754,-2.610253866866887,0.11708504290317308,1.661926099494074,0.06358895367080376,-0.4334795450313125,0.2581461514602102,0.5842822509907212,-0.15377855875444413,1.780620541054555,-0.3768005767007224,-0.3768005767007224,0.4141504853427531,-0.5287933290146903,0.2055167698607001,0.04568305057423946,0.7346320169701449,-0.4334795450313125,-0.22747447582986668,-0.008258738440055532,1.541660105153763,0.3624587383041505,-0.3956516265185736,-0.3768005767007224,0.08145780404230812,-0.471476648351972,0.06358895367080376,0.11708504290317308,-0.06254040557376016,-0.11716687434726772,-0.8611490148593872,-0.3768005767007224,0.5505191412386632,0.24063844353304098,0.17025232429825055,0.8334597491992295,-0.664061673412729,-0.41454454507068694,5.017262595389153,1.7510917082093325,-0.15377855875444413,0.5842822509907212,-0.1905472446215371,-0.5479853796195989,0.5166255731433357,-0.22747447582986668,-0.044408450650093925,-0.8611490148593872,-0.3768005767007224,0.9311961834886229,-0.3956516265185736,0.9635371984080219,-0.17214318056581754,1.4809227807404823,0.08145780404230812,2.8641358146662417,-0.35799118461648044,4.150393709731816,0.06358895367080376,-0.15377855875444413,0.4313132764939044,1.1235025176038205
| 2,812
|
Schizophrenia
| 7
| 18
| 2.590691
| 0.009578
|
Q9NZJ7,P07602,P16615,P21964,O43681,P04062,Q9BQE5
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
98,132,144,149,182,55,26
|
182,2077,227,55,132,144,149,1696,1936,1901,2020,983,1988,26,835,2561,2110,98
|
1.373639236931527,-0.4334795450313125,1.1235025176038205,2.9684696908889308,1.7510917082093325,1.6768478836617977,1.6469797626441487,-0.2459980349044931,-0.35799118461648044,-0.33922324092093464,-0.3956516265185736,0.06358895367080376,-0.3768005767007224,4.069774341527857,0.15256614703595497,-0.7817584262207112,-0.4334795450313125,2.226542769012561
| 2,812
|
Cytochrome complex assembly
| 6
| 8
| 2.583162
| 0.00979
|
Q15070,Q7KZN9,O43819,P47985,Q6DKK2,Q9Y2R0
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
130,133,200,147,180,20
|
200,208,147,130,180,133,1810,20
|
1.2494429822888136,1.2024227010441528,1.661926099494074,1.7658680852573057,1.389043853750546,1.7510917082093325,-0.283166031185393,4.150393709731816
| 2,812
|
Alzheimers disease
| 20
| 71
| 2.571071
| 0.010138
|
P12236,P60900,P16615,P45880,P21796,O95197,P28074,Q9Y277,P49327,O00487,Q9NQC3,Q9UJX6,P28072,P49720,Q92542,Q02750,P20618,P05141,P31751,Q08752
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
261,263,144,17,23,25,530,164,412,547,51,463,205,469,222,360,488,487,373,509
|
1272,547,1530,954,860,25,1310,487,1400,1921,1311,864,261,693,144,1922,724,1586,1195,488,23,743,1590,969,1115,641,1159,205,530,2085,1591,373,1046,1925,971,1119,815,17,1013,1643,412,469,553,2006,263,871,702,1205,2413,872,1209,360,1285,2722,1457,509,2011,1250,1287,1981,222,888,1298,2304,1989,1766,1470,51,463,897,164
|
-0.0807106708667228,0.3969539001942955,-0.1905472446215371,0.06358895367080376,0.11708504290317308,4.092876418130871,-0.0989194316256046,0.46553808003374114,-0.13545318694325917,-0.35799118461648044,-0.0989194316256046,0.11708504290317308,0.9635371984080219,0.24063844353304098,1.6768478836617977,-0.35799118461648044,0.22309537077734548,-0.2089909446401189,-0.044408450650093925,0.46553808003374114,4.127427393456283,0.2055167698607001,-0.2089909446401189,0.06358895367080376,-0.008258738440055532,0.2930561203226198,-0.026314622385095934,1.218123559434321,0.4141504853427531,-0.4334795450313125,-0.2089909446401189,0.6346847947097649,0.027739919068620857,-0.35799118461648044,0.06358895367080376,-0.008258738440055532,0.15256614703595497,4.287071828555498,0.04568305057423946,-0.22747447582986668,0.5842822509907212,0.49962950681326135,0.3969539001942955,-0.3956516265185736,0.9635371984080219,0.11708504290317308,0.24063844353304098,-0.044408450650093925,-0.6446044732945461,0.11708504290317308,-0.044408450650093925,0.6681267102911925,-0.0807106708667228,-1.1864793952065424,-0.15377855875444413,0.44844242471808454,-0.3956516265185736,-0.06254040557376016,-0.0807106708667228,-0.3768005767007224,1.1551542156307362,0.11708504290317308,-0.0807106708667228,-0.5479853796195989,-0.3768005767007224,-0.2645618200989318,-0.15377855875444413,3.071664222481722,0.5166255731433357,0.11708504290317308,1.5265139768993863
| 2,812
|
acyltransferase
| 8
| 15
| 2.560821
| 0.010443
|
P23786,P14324,Q99943,Q9BWD1,Q8NCC3,Q92696,Q8NF37,P49356
|
Functions
|
Panther Protein class
|
panther_protein_class
|
128,320,103,76,43,114,179,93
|
485,320,128,1589,1854,746,93,1820,571,43,179,379,114,103,76
|
0.46553808003374114,0.7676975668159858,1.780620541054555,-0.2089909446401189,-0.3204965379073243,0.2055167698607001,2.2545833119587817,-0.30181086948961583,0.37972336891623004,3.1864309983263617,1.4044221691939036,0.6346847947097649,1.970265053697904,2.1560667669732525,2.557560972127124
| 2,812
|
Neuron death
| 12
| 62
| 2.554979
| 0.010619
|
O76024,P09601,Q99720,Q96A26,Q4ZIN3,Q9UMX5,Q15392,P04062,Q01105,Q92542,O95831,P50897
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
227,37,135,39,74,141,150,55,86,222,158,95
|
808,622,1034,227,158,55,1920,1310,1399,1400,1490,1083,1536,37,1885,602,1922,1924,373,1925,1361,676,1363,412,1855,95,2435,2007,1745,1090,871,437,1125,1209,86,1936,251,2196,1864,2294,1250,2511,909,150,74,222,1465,39,2450,1988,2139,135,2589,836,1384,714,1477,1957,141,431,2590,2069
|
0.15256614703595497,0.31045870212056503,0.027739919068620857,1.1235025176038205,1.5567809266545096,2.9684696908889308,-0.35799118461648044,-0.0989194316256046,-0.13545318694325917,-0.13545318694325917,-0.17214318056581754,0.009759382165723819,-0.1905472446215371,3.4735930042919643,-0.33922324092093464,0.3278265608377056,-0.35799118461648044,-0.35799118461648044,0.6346847947097649,-0.35799118461648044,-0.11716687434726772,0.2581461514602102,-0.11716687434726772,0.5842822509907212,-0.3204965379073243,2.226542769012561,-0.664061673412729,-0.3956516265185736,-0.2645618200989318,0.009759382165723819,0.11708504290317308,0.5505191412386632,-0.008258738440055532,-0.044408450650093925,2.3797253533192024,-0.35799118461648044,1.0118291637604662,-0.490539185592664,-0.3204965379073243,-0.5479853796195989,-0.06254040557376016,-0.7423429355985278,0.09928977608158417,1.6469797626441487,2.611604127146138,1.1551542156307362,-0.15377855875444413,3.448961903318223,-0.664061673412729,-0.3768005767007224,-0.45245684076640463,1.7510917082093325,-0.8213597823323313,0.15256614703595497,-0.11716687434726772,0.24063844353304098,-0.15377855875444413,-0.35799118461648044,1.721466835279003,0.5674169318211052,-0.8213597823323313,-0.41454454507068694
| 2,812
|
Cation transport
| 46
| 140
| 2.554958
| 0.01062
|
P20020,Q70HW3,Q7KZN9,Q9Y4W6,P30825,Q4KMQ2,Q01650,P30536,P16615,P13073,P47985,P42858,P21796,P51809,P78417,P56385,O75964,O15173,Q9UNH7,P61421,O14936,P24539,O75844,Q9HD20,P05023,P36543,Q9UDW1,P56134,O00429,P05026,Q9HC21,O43772,Q99623,O95202,O43865,Q9UM00,O76024,Q9H2H9,Q96ES6,P05141,P51790,Q13423,Q9Y619,Q96GC9,Q13555,Q8NEW0
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
257,5,133,526,386,522,520,14,144,146,147,275,23,397,414,413,34,36,431,424,299,435,57,60,184,313,64,447,465,467,350,89,248,92,476,226,227,239,112,487,242,510,119,122,511,125
|
2769,465,1679,1680,299,36,1846,89,586,476,997,691,1276,1392,1486,2533,57,598,34,227,92,590,2536,1236,184,467,487,1081,1440,843,2312,1921,1082,924,723,1156,863,602,864,146,964,144,1113,2158,2751,257,1239,673,694,674,2538,23,435,1086,2160,2210,2289,1591,14,867,386,605,1046,1925,1927,532,313,1314,275,1408,2254,147,972,1546,242,397,2652,2258,1697,1051,447,413,2044,424,870,537,727,414,975,1209,1551,520,1822,569,2542,2782,1457,2368,1323,510,511,1980,611,1982,522,1134,5,133,1514,1902,1098,125,2601,1518,112,122,887,834,2737,2139,248,1224,2748,239,2064,760,350,60,2280,64,1477,787,859,2146,226,2328,431,1149,526,119
|
-1.6338631244210937,0.49962950681326135,-0.2459980349044931,-0.2459980349044931,0.8334597491992295,3.498161016050837,-0.3204965379073243,2.2964854074361383,0.34515985407120203,0.48260039141735633,0.04568305057423946,0.24063844353304098,-0.0807106708667228,-0.13545318694325917,-0.17214318056581754,-0.762027572092384,2.8772408406430023,0.3278265608377056,3.55930743245453,1.1235025176038205,2.2545833119587817,0.34515985407120203,-0.762027572092384,-0.06254040557376016,1.3582082159271402,0.49962950681326135,0.46553808003374114,0.009759382165723819,-0.15377855875444413,0.13484377635600422,-0.5672210487658126,-0.35799118461648044,0.009759382165723819,0.08145780404230812,0.22309537077734548,-0.026314622385095934,0.11708504290317308,0.3278265608377056,0.11708504290317308,1.661926099494074,0.06358895367080376,1.6768478836617977,-0.008258738440055532,-0.471476648351972,-1.4177846515000923,0.995760955144229,-0.06254040557376016,0.2581461514602102,0.24063844353304098,0.2581461514602102,-0.762027572092384,4.127427393456283,0.5505191412386632,0.009759382165723819,-0.471476648351972,-0.5096446720406466,-0.5479853796195989,-0.2089909446401189,4.433024287479104,0.11708504290317308,0.6179160419293773,0.3278265608377056,0.027739919068620857,-0.35799118461648044,-0.35799118461648044,0.4141504853427531,0.7841840310190734,-0.0989194316256046,0.9149813991987668,-0.13545318694325917,-0.5287933290146903,1.661926099494074,0.06358895367080376,-0.1905472446215371,1.043878838847843,0.6011152406986369,-0.9614575627830952,-0.5287933290146903,-0.2459980349044931,0.027739919068620857,0.5335887363165991,0.5842822509907212,-0.41454454507068694,0.5674169318211052,0.11708504290317308,0.4141504853427531,0.22309537077734548,0.5842822509907212,0.06358895367080376,-0.044408450650093925,-0.1905472446215371,0.4313132764939044,-0.30181086948961583,0.37972336891623004,-0.762027572092384,-1.9009500015564165,-0.15377855875444413,-0.6058241514720926,-0.0989194316256046,0.44844242471808454,0.44844242471808454,-0.3768005767007224,0.3278265608377056,-0.3768005767007224,0.4313132764939044,-0.008258738440055532,5.017262595389153,1.7510917082093325,-0.17214318056581754,-0.33922324092093464,0.009759382165723819,1.8540270682769622,-0.8412307870350623,-0.17214318056581754,1.984691640902663,1.8686378297720425,0.11708504290317308,0.15256614703595497,-1.248922783915979,-0.45245684076640463,1.0278684187598215,-0.044408450650093925,-1.375243635959107,1.0758136453276277,-0.41454454507068694,0.2055167698607001,0.7014420888364408,2.8378709383397114,-0.5287933290146903,2.732071824115165,-0.15377855875444413,0.18790247626968237,0.13484377635600422,-0.45245684076640463,1.1393423790368928,-0.5672210487658126,0.5674169318211052,-0.008258738440055532,0.4313132764939044,1.8832252764522284
| 2,812
|
Biliary tract abnormality
| 9
| 25
| 2.548957
| 0.010805
|
Q9NZJ7,P07602,P09601,Q10713,Q5XKP0,O43681,P04062,O95202,Q14108
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
98,132,37,138,212,182,55,92,62
|
182,92,2123,371,55,132,37,638,1689,1641,471,138,1458,62,235,212,322,1619,2303,2464,948,98,2671,1810,2387
|
1.373639236931527,2.2545833119587817,-0.45245684076640463,0.6346847947097649,2.9684696908889308,1.7510917082093325,3.4735930042919643,0.2930561203226198,-0.2459980349044931,-0.22747447582986668,0.49962950681326135,1.7362913212685769,-0.15377855875444413,2.7453620538410717,1.0917382653656786,1.186694264872841,0.7676975668159858,-0.2089909446401189,-0.5479853796195989,-0.6835638805894443,0.08145780404230812,2.226542769012561,-1.0019206995296568,-0.283166031185393,-0.6058241514720926
| 2,812
|
Oxidoreductase activity acting on the ch ch group of donors nad or nadp as acceptor
| 7
| 14
| 2.543965
| 0.01096
|
P49327,Q8N4Q0,Q14739,Q9NZ01,Q8N8N7,Q15392,Q9H7Z7
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
412,4,235,115,339,150,94
|
1044,1161,412,472,235,1417,150,4,339,855,2027,94,115,857
|
0.027739919068620857,-0.026314622385095934,0.5842822509907212,0.49962950681326135,1.0917382653656786,-0.13545318694325917,1.6469797626441487,5.194333871316421,0.7180526668602384,0.13484377635600422,-0.3956516265185736,2.2545833119587817,1.970265053697904,0.13484377635600422
| 2,812
|
Cellular homeostasis
| 27
| 129
| 2.54276
| 0.010998
|
Q9Y487,P20020,Q8N511,P16615,P42858,Q96A33,P09601,Q9NQC3,P52789,Q93050,P05023,Q9HD20,Q9Y263,O43819,Q8N5M9,Q15120,O75880,O75503,P10253,P51572,O95202,P50897,Q9UM00,O76024,P51790,Q07820,Q8NEW0
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
3,257,12,144,275,157,37,51,307,53,184,60,325,200,334,83,208,213,214,215,92,95,226,227,242,251,125
|
1813,2484,2284,1680,200,997,2551,691,213,208,767,227,92,2000,739,2535,2536,1188,184,467,1440,843,2332,1350,1082,862,1351,37,962,214,1004,964,928,693,144,2568,1113,2751,1238,257,1043,2409,2210,2488,2289,2085,2005,1198,1495,867,792,1314,275,1363,95,1856,1889,215,242,700,307,1201,2652,1697,1051,2637,1018,424,537,727,1053,1125,414,1209,777,251,1457,521,2707,1166,2545,1058,1213,83,1980,1418,1757,1168,2133,849,522,495,333,1514,1169,1945,1902,417,12,334,125,2104,2601,53,157,2178,2450,887,2737,2610,1382,1224,583,1069,60,1668,51,2280,858,1477,787,859,226,1809,325,805,3,526,1340
|
-0.30181086948961583,-0.7227042705874989,-0.5479853796195989,-0.2459980349044931,1.2494429822888136,0.04568305057423946,-0.7817584262207112,0.24063844353304098,1.1709381402052799,1.2024227010441528,0.18790247626968237,1.1235025176038205,2.2545833119587817,-0.3956516265185736,0.2055167698607001,-0.762027572092384,-0.762027572092384,-0.044408450650093925,1.3582082159271402,0.49962950681326135,-0.15377855875444413,0.13484377635600422,-0.5865005631893707,-0.11716687434726772,0.009759382165723819,0.11708504290317308,-0.11716687434726772,3.4735930042919643,0.06358895367080376,1.1709381402052799,0.04568305057423946,0.06358895367080376,0.08145780404230812,0.24063844353304098,1.6768478836617977,-0.801535746199426,-0.008258738440055532,-1.4177846515000923,-0.06254040557376016,0.995760955144229,0.027739919068620857,-0.6446044732945461,-0.5096446720406466,-0.7227042705874989,-0.5479853796195989,-0.4334795450313125,-0.3956516265185736,-0.044408450650093925,-0.17214318056581754,0.11708504290317308,0.17025232429825055,-0.0989194316256046,0.9149813991987668,-0.11716687434726772,2.226542769012561,-0.3204965379073243,-0.33922324092093464,1.1709381402052799,1.043878838847843,0.24063844353304098,0.8170649925871301,-0.044408450650093925,-0.9614575627830952,-0.2459980349044931,0.027739919068620857,-0.9211896151418975,0.04568305057423946,0.5674169318211052,0.4141504853427531,0.22309537077734548,0.027739919068620857,-0.008258738440055532,0.5842822509907212,-0.044408450650093925,0.18790247626968237,1.0118291637604662,-0.15377855875444413,0.4313132764939044,-1.1245031466065663,-0.026314622385095934,-0.762027572092384,0.027739919068620857,-0.044408450650093925,2.448526345052684,-0.3768005767007224,-0.13545318694325917,-0.2645618200989318,-0.026314622385095934,-0.45245684076640463,0.13484377635600422,0.4313132764939044,0.46553808003374114,0.7346320169701449,-0.17214318056581754,-0.026314622385095934,-0.35799118461648044,-0.33922324092093464,0.5842822509907212,4.466400716267569,0.7346320169701449,1.8540270682769622,-0.4334795450313125,-0.8412307870350623,3.0459708542969364,1.571876537624149,-0.471476648351972,-0.664061673412729,0.11708504290317308,-1.248922783915979,-0.8611490148593872,-0.11716687434726772,-0.044408450650093925,0.3624587383041505,0.027739919068620857,2.8378709383397114,-0.22747447582986668,3.071664222481722,-0.5287933290146903,0.13484377635600422,-0.15377855875444413,0.18790247626968237,0.13484377635600422,1.1393423790368928,-0.283166031185393,0.7676975668159858,0.17025232429825055,5.214962353364934,0.4313132764939044,-0.0989194316256046
| 2,812
|
Intracellular protein transmembrane transport
| 8
| 18
| 2.537395
| 0.011168
|
O60830,Q99595,O75381,Q15388,P31751,Q15629,O95831,O14925
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
0,1,145,348,373,124,158,255
|
255,383,0,145,528,158,768,1401,373,2613,1017,870,348,124,704,1,785,516
|
0.995760955144229,0.6179160419293773,5.214962353364934,1.661926099494074,0.4141504853427531,1.5567809266545096,0.18790247626968237,-0.13545318694325917,0.6346847947097649,-0.8811147225178695,0.04568305057423946,0.11708504290317308,0.7014420888364408,1.8540270682769622,0.24063844353304098,5.214962353364934,0.18790247626968237,0.44844242471808454
| 2,812
|
Passive transmembrane transporter activity
| 12
| 28
| 2.534211
| 0.01127
|
P56385,P24539,O75964,Q9Y277,P56134,Q9UM00,Q4KMQ2,P45880,Q99797,P51790,P21796,Q9C0H2
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
413,435,34,164,447,226,522,17,443,242,23,90
|
807,598,34,768,843,2312,1082,23,435,2160,532,1314,17,972,242,2652,447,413,870,1209,522,1518,443,2324,90,226,164,1340
|
0.15256614703595497,0.3278265608377056,3.55930743245453,0.18790247626968237,0.13484377635600422,-0.5672210487658126,0.009759382165723819,4.127427393456283,0.5505191412386632,-0.471476648351972,0.4141504853427531,-0.0989194316256046,4.287071828555498,0.06358895367080376,1.043878838847843,-0.9614575627830952,0.5335887363165991,0.5842822509907212,0.11708504290317308,-0.044408450650093925,0.4313132764939044,-0.17214318056581754,0.5505191412386632,-0.5672210487658126,2.2964854074361383,1.1393423790368928,1.5265139768993863,-0.0989194316256046
| 2,812
|
Organic acid transmembrane transporter activity
| 9
| 20
| 2.5337
| 0.011287
|
P33527,P08183,P30825,Q9BQT8,Q02978,Q9H2D1,Q9H2H9,Q9Y619,Q9UBX3
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
411,71,386,77,271,48,239,119,59
|
1680,861,71,924,386,411,607,1819,520,271,611,2054,834,77,48,239,760,59,430,119
|
-0.2459980349044931,0.11708504290317308,2.665336704465738,0.08145780404230812,0.6179160419293773,0.5842822509907212,0.3278265608377056,-0.30181086948961583,0.4313132764939044,0.9311961834886229,0.3278265608377056,-0.41454454507068694,0.15256614703595497,2.5440011741485096,3.110074180270112,1.0758136453276277,0.2055167698607001,2.8641358146662417,0.5674169318211052,1.8832252764522284
| 2,812
|
Sterol binding
| 7
| 17
| 2.513286
| 0.011961
|
O95772,P30536,P45880,Q9BZF3,P21796,O15118,Q14108
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
11,14,17,117,23,56,62
|
56,636,588,11,1082,23,2409,551,14,17,2509,62,221,357,2786,349,117
|
2.916446962695746,0.2930561203226198,0.34515985407120203,4.707778885717138,0.009759382165723819,4.127427393456283,-0.6446044732945461,0.3969539001942955,4.433024287479104,4.287071828555498,-0.7423429355985278,2.7453620538410717,1.1551542156307362,0.6848001484363205,-2.1537802662741563,0.7014420888364408,1.8977894929892263
| 2,812
|
Polyneuropathy
| 8
| 17
| 2.510164
| 0.012068
|
Q9NZJ7,Q15041,P07602,P03886,Q15120,Q8N2K0,Q9HC21,O95831
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
98,195,132,100,83,247,350,158
|
343,565,158,100,1584,132,724,1924,605,1602,195,83,1760,247,350,98,666
|
0.7014420888364408,0.37972336891623004,1.5567809266545096,2.1984168906874886,-0.2089909446401189,1.7510917082093325,0.22309537077734548,-0.35799118461648044,0.3278265608377056,-0.2089909446401189,1.3117556902397782,2.448526345052684,-0.2645618200989318,1.0278684187598215,0.7014420888364408,2.226542769012561,0.2756186567217988
| 2,812
|
Endoplasmic reticulum
| 122
| 407
| 2.504177
| 0.012274
|
Q7Z2K6,Q06136,O95772,Q8N511,P30536,P07099,O60725,O95197,Q9BQE5,P43307,P30519,Q86XL3,O75608,O15173,P09601,P37268,Q5BJF2,Q16850,Q9UQB8,Q9BRR6,Q96G23,Q8TCT9,Q9NQC3,P04062,O15118,O75844,Q9HD20,Q14108,Q9Y5M8,Q4ZIN3,P67812,P80303,Q8TB61,Q13510,Q01105,Q9P2W9,P51648,Q99943,Q9Y282,P16435,P55327,O95470,Q9NZ01,Q9BZF3,O00264,Q96GC9,A1L0T0,P35613,Q15629,O15260,Q15800,Q99720,Q9BUN8,Q9UMX5,P16615,Q15392,O15269,P48449,P84157,Q96A33,P46977,Q10472,Q96A57,Q9P035,Q07065,Q15005,Q8NF37,O43493,O43681,P05023,Q9H3N1,Q15041,P01889,Q9Y6K0,P57088,P04439,Q9UBU6,Q9BT22,O75503,P51572,Q14849,Q92542,Q9UM00,O76024,Q6RW13,Q96KC8,Q14739,Q13190,Q14257,Q14534,Q86UE4,O95070,Q8N2K0,P10619,O14681,P42858,Q9NPA0,Q9Y3B3,Q70UQ0,Q9Y4P3,P52789,Q96HY6,P27824,Q02818,Q9NZ08,Q96RQ1,Q9Y3A6,Q8N5M9,O43292,Q5VV42,Q9Y394,Q9BZF1,Q9UNK0,P48723,Q8TED1,O15258,P52292,Q02750,Q9Y320,Q9H6E4,Q9NTJ5,Q969V3
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
6,9,11,12,14,13,19,25,26,27,31,32,33,36,37,38,40,42,44,45,47,49,51,55,56,57,60,62,66,74,75,78,79,85,86,87,91,103,104,108,111,113,115,117,118,122,120,121,124,127,129,135,136,141,144,150,151,154,156,157,159,162,169,172,176,178,179,181,182,184,190,195,201,202,203,204,210,209,213,215,221,222,226,227,229,230,235,233,240,241,243,244,247,245,266,275,281,282,284,298,307,309,310,311,317,315,326,334,336,338,342,349,351,346,356,353,359,360,361,368,381,380
|
120,2776,118,465,2549,2330,738,266,2687,635,1632,56,36,353,127,151,717,2633,994,336,1437,181,182,432,476,2406,996,19,1234,1683,999,1344,2656,636,213,33,789,57,1034,227,1685,2627,2390,588,1488,1001,244,25,2000,599,922,113,923,959,466,11,2001,903,740,1687,1636,201,2742,55,204,1399,504,1346,184,1035,455,13,529,2363,1736,37,1537,591,245,2156,1585,1038,1039,1278,928,108,144,1922,639,2715,1114,2432,1043,2409,551,1405,2315,968,695,2250,1444,970,845,2210,2488,310,2289,2085,1445,675,846,1407,31,604,14,867,1497,506,793,1010,121,2086,38,422,1886,642,1119,275,27,1742,2412,1501,159,1502,154,346,817,1162,697,625,470,533,1645,1451,1364,215,91,397,359,700,307,2256,2336,1974,1696,2652,932,1820,906,111,2127,203,2613,1241,1745,1016,1017,535,1317,1367,2009,1242,870,848,2509,1203,1548,1243,1368,2129,538,1699,776,1861,727,1893,1054,75,78,1284,2166,2555,156,399,86,360,1700,311,2439,9,1211,2168,176,2341,162,1702,1749,2195,1323,425,2545,233,2170,1249,85,511,1896,62,2457,240,1556,241,1653,235,221,1095,178,749,195,778,1867,1559,1509,1980,2219,150,2616,1941,415,124,1868,657,129,1418,42,911,74,629,40,912,427,338,2174,1655,2221,1020,2054,229,571,1901,731,284,495,6,1255,1377,661,243,2017,32,1614,2643,1514,2702,440,881,247,12,1137,334,1946,755,1947,1170,2515,481,1257,2495,179,1219,1295,79,882,1762,1565,49,2475,356,733,1799,1464,1903,222,1139,2601,379,756,1618,709,983,460,1519,1465,380,1173,157,169,451,2138,710,47,122,887,309,230,404,497,315,617,1951,2139,1952,135,443,103,26,45,583,2420,209,1226,1425,136,2324,562,349,117,987,2748,2753,1522,890,2141,190,368,2499,1105,803,60,1383,281,51,407,990,381,2527,2386,115,317,172,2204,2308,1672,87,1574,857,1181,210,2327,516,1232,1477,445,2186,226,141,1577,351,1808,44,951,104,689,1433,361,342,326,282,1812,2069,298,66,527,2310,900,202,1880
|
1.8686378297720425,-1.7219202513137202,1.8832252764522284,0.49962950681326135,-0.7817584262207112,-0.5865005631893707,0.2055167698607001,0.9473814090258249,-1.062986143976836,0.2930561203226198,-0.22747447582986668,2.916446962695746,3.498161016050837,0.6848001484363205,1.780620541054555,1.617013061048013,0.22309537077734548,-0.9211896151418975,0.04568305057423946,0.7180526668602384,-0.15377855875444413,1.373639236931527,1.373639236931527,0.5505191412386632,0.48260039141735633,-0.6446044732945461,0.04568305057423946,4.207574767297518,-0.06254040557376016,-0.2459980349044931,0.04568305057423946,-0.11716687434726772,-0.9816645976999411,0.2930561203226198,1.1709381402052799,3.75240658285758,0.17025232429825055,2.8772408406430023,0.027739919068620857,1.1235025176038205,-0.2459980349044931,-0.9011281689088609,-0.6251920440620977,0.34515985407120203,-0.17214318056581754,0.04568305057423946,1.0278684187598215,4.092876418130871,-0.3956516265185736,0.3278265608377056,0.08145780404230812,1.970265053697904,0.08145780404230812,0.06358895367080376,0.49962950681326135,4.707778885717138,-0.3956516265185736,0.09928977608158417,0.2055167698607001,-0.2459980349044931,-0.22747447582986668,1.2494429822888136,-1.2908152269601356,2.9684696908889308,1.218123559434321,-0.13545318694325917,0.44844242471808454,-0.11716687434726772,1.3582082159271402,0.027739919068620857,0.5166255731433357,4.433024287479104,0.4141504853427531,-0.6058241514720926,-0.2645618200989318,3.4735930042919643,-0.1905472446215371,0.34515985407120203,1.0278684187598215,-0.471476648351972,-0.2089909446401189,0.027739919068620857,0.027739919068620857,-0.0807106708667228,0.08145780404230812,2.0850480342379543,1.6768478836617977,-0.35799118461648044,0.2930561203226198,-1.1657691353785238,-0.008258738440055532,-0.664061673412729,0.027739919068620857,-0.6446044732945461,0.3969539001942955,-0.13545318694325917,-0.5672210487658126,0.06358895367080376,0.24063844353304098,-0.5287933290146903,-0.15377855875444413,0.06358895367080376,0.13484377635600422,-0.5096446720406466,-0.7227042705874989,0.800639796258553,-0.5479853796195989,-0.4334795450313125,-0.15377855875444413,0.2581461514602102,0.13484377635600422,-0.13545318694325917,3.80008400175991,0.3278265608377056,4.433024287479104,0.11708504290317308,-0.17214318056581754,0.44844242471808454,0.17025232429825055,0.04568305057423946,1.8686378297720425,-0.4334795450313125,3.4735930042919643,0.5674169318211052,-0.33922324092093464,0.2930561203226198,-0.008258738440055532,0.9149813991987668,4.01177866837398,-0.2645618200989318,-0.6446044732945461,-0.17214318056581754,1.5567809266545096,-0.17214318056581754,1.601992510014427,0.7014420888364408,0.15256614703595497,-0.026314622385095934,0.24063844353304098,0.31045870212056503,0.49962950681326135,0.4141504853427531,-0.22747447582986668,-0.15377855875444413,-0.11716687434726772,1.1709381402052799,2.2685717667150977,0.6011152406986369,0.6681267102911925,0.24063844353304098,0.8170649925871301,-0.5287933290146903,-0.5865005631893707,-0.3768005767007224,-0.2459980349044931,-0.9614575627830952,0.08145780404230812,-0.30181086948961583,0.09928977608158417,1.984691640902663,-0.45245684076640463,1.2337969500687216,-0.8811147225178695,-0.06254040557376016,-0.2645618200989318,0.04568305057423946,0.04568305057423946,0.4141504853427531,-0.0989194316256046,-0.11716687434726772,-0.3956516265185736,-0.06254040557376016,0.11708504290317308,0.13484377635600422,-0.7423429355985278,-0.044408450650093925,-0.1905472446215371,-0.06254040557376016,-0.11716687434726772,-0.45245684076640463,0.4141504853427531,-0.2459980349044931,0.18790247626968237,-0.3204965379073243,0.22309537077734548,-0.33922324092093464,0.027739919068620857,2.557560972127124,2.5304216424297428,-0.0807106708667228,-0.471476648351972,-0.7817584262207112,1.571876537624149,0.6011152406986369,2.3797253533192024,0.6681267102911925,-0.2459980349044931,0.800639796258553,-0.664061673412729,4.772602732969393,-0.044408450650093925,-0.471476648351972,1.4197742854475608,-0.5865005631893707,1.5265139768993863,-0.2459980349044931,-0.2645618200989318,-0.490539185592664,-0.0989194316256046,0.5674169318211052,-0.762027572092384,1.0917382653656786,-0.471476648351972,-0.06254040557376016,2.393526363136978,0.44844242471808454,-0.33922324092093464,2.7453620538410717,-0.6835638805894443,1.0598605419718725,-0.1905472446215371,1.0598605419718725,-0.22747447582986668,1.0917382653656786,1.1551542156307362,0.009759382165723819,1.4044221691939036,0.2055167698607001,1.3117556902397782,0.18790247626968237,-0.3204965379073243,-0.1905472446215371,-0.17214318056581754,-0.3768005767007224,-0.5096446720406466,1.6469797626441487,-0.8811147225178695,-0.35799118461648044,0.5842822509907212,1.8540270682769622,-0.3204965379073243,0.2756186567217988,1.780620541054555,-0.13545318694325917,3.2495966741269706,0.09928977608158417,2.611604127146138,0.31045870212056503,3.362250839676791,0.09928977608158417,0.5674169318211052,0.7180526668602384,-0.471476648351972,-0.22747447582986668,-0.5096446720406466,0.04568305057423946,-0.41454454507068694,1.1235025176038205,0.37972336891623004,-0.33922324092093464,0.22309537077734548,0.8824626599674397,0.46553808003374114,5.006748745407826,-0.06254040557376016,-0.11716687434726772,0.2756186567217988,1.043878838847843,-0.3956516265185736,3.7881866490986087,-0.2089909446401189,-0.9412993245634615,-0.17214318056581754,-1.1039468355518776,0.5505191412386632,0.11708504290317308,1.0278684187598215,4.466400716267569,-0.008258738440055532,0.7346320169701449,-0.35799118461648044,0.2055167698607001,-0.35799118461648044,-0.026314622385095934,-0.7423429355985278,0.48260039141735633,-0.06254040557376016,-0.7227042705874989,1.4044221691939036,-0.044408450650093925,-0.0807106708667228,2.489563986964071,0.11708504290317308,-0.2645618200989318,-0.1905472446215371,3.097288135737863,-0.7031113329486606,0.6848001484363205,0.22309537077734548,-0.283166031185393,-0.15377855875444413,-0.33922324092093464,1.1551542156307362,-0.008258738440055532,-0.8412307870350623,0.6346847947097649,0.2055167698607001,-0.2089909446401189,0.24063844353304098,0.06358895367080376,0.5166255731433357,-0.17214318056581754,-0.15377855875444413,0.6346847947097649,-0.026314622385095934,1.571876537624149,1.4961454123614193,0.5335887363165991,-0.45245684076640463,0.24063844353304098,3.1228430207611986,1.8686378297720425,0.11708504290317308,0.8170649925871301,1.1235025176038205,0.6011152406986369,0.46553808003374114,0.7841840310190734,0.3278265608377056,-0.35799118461648044,-0.45245684076640463,-0.35799118461648044,1.7510917082093325,0.5505191412386632,2.1560667669732525,4.069774341527857,3.161046843731062,0.3624587383041505,-0.6446044732945461,1.2024227010441528,-0.044408450650093925,-0.13545318694325917,1.7510917082093325,-0.5672210487658126,0.3969539001942955,0.7014420888364408,1.8977894929892263,0.06358895367080376,-1.375243635959107,-1.4177846515000923,-0.17214318056581754,0.11708504290317308,-0.45245684076640463,1.3427506872987998,0.6514216381177684,-0.7227042705874989,0.009759382165723819,0.17025232429825055,2.8378709383397114,-0.11716687434726772,0.8987369327594061,3.071664222481722,0.6011152406986369,0.06358895367080376,0.6346847947097649,-0.7423429355985278,-0.6058241514720926,1.970265053697904,0.7841840310190734,1.4504003260418334,-0.490539185592664,-0.5479853796195989,-0.22747447582986668,2.3520616312023908,-0.1905472446215371,0.13484377635600422,-0.026314622385095934,1.2024227010441528,-0.5672210487658126,0.44844242471808454,-0.044408450650093925,-0.15377855875444413,0.5505191412386632,-0.471476648351972,1.1393423790368928,1.721466835279003,-0.1905472446215371,0.7014420888364408,-0.283166031185393,3.1864309983263617,0.08145780404230812,2.1560667669732525,0.2581461514602102,-0.13545318694325917,0.6681267102911925,0.7180526668602384,0.7676975668159858,0.8987369327594061,-0.283166031185393,-0.41454454507068694,0.8498241944386672,2.6920877924017246,0.4313132764939044,-0.5479853796195989,0.11708504290317308,1.2494429822888136,-0.3204965379073243
| 2,812
|
Elevated hepatic transaminase
| 25
| 84
| 2.50003
| 0.012418
|
P23786,Q9H845,Q10713,Q8N511,P55263,P49748,Q14746,Q9UJS0,Q15067,Q9Y285,O75431,Q92889,P01889,P40939,O75880,Q5XKP0,Q13510,P10253,O43772,P40855,Q14739,Q9Y619,Q00059,P06737,P22695
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
128,265,138,12,18,160,426,430,304,318,65,322,201,331,208,212,85,214,89,345,235,119,377,372,250
|
2776,89,1234,65,597,486,208,1533,201,1399,372,723,1535,962,214,2794,864,2727,1404,673,250,929,128,1159,904,2042,793,1592,1785,1886,345,331,1694,160,1122,471,2008,1820,18,2437,1977,1017,874,2614,377,1602,1603,2573,1371,138,85,235,426,304,1418,729,438,1289,939,212,1761,754,2662,1462,12,1220,322,2418,2610,1104,595,265,1227,988,948,1672,430,1810,318,764,1578,1434,1528,119
|
-1.7219202513137202,2.2964854074361383,-0.06254040557376016,2.6920877924017246,0.3278265608377056,0.46553808003374114,1.2024227010441528,-0.1905472446215371,1.2494429822888136,-0.13545318694325917,0.6346847947097649,0.22309537077734548,-0.1905472446215371,0.06358895367080376,1.1709381402052799,-2.610253866866887,0.11708504290317308,-1.2280559205447314,-0.13545318694325917,0.2581461514602102,1.0118291637604662,0.08145780404230812,1.780620541054555,-0.026314622385095934,0.09928977608158417,-0.41454454507068694,0.17025232429825055,-0.2089909446401189,-0.283166031185393,-0.33922324092093464,0.7014420888364408,0.7346320169701449,-0.2459980349044931,1.541660105153763,-0.008258738440055532,0.49962950681326135,-0.3956516265185736,-0.30181086948961583,4.287071828555498,-0.664061673412729,-0.3768005767007224,0.04568305057423946,0.11708504290317308,-0.8811147225178695,0.6346847947097649,-0.2089909446401189,-0.2089909446401189,-0.801535746199426,-0.11716687434726772,1.7362913212685769,2.393526363136978,1.0917382653656786,0.5674169318211052,0.8334597491992295,-0.13545318694325917,0.22309537077734548,0.5505191412386632,-0.0807106708667228,0.08145780404230812,1.186694264872841,-0.2645618200989318,0.2055167698607001,-0.9816645976999411,-0.15377855875444413,4.466400716267569,-0.044408450650093925,0.7676975668159858,-0.6446044732945461,-0.8611490148593872,0.009759382165723819,0.34515985407120203,0.9635371984080219,-0.044408450650093925,0.06358895367080376,0.08145780404230812,-0.22747447582986668,0.5674169318211052,-0.283166031185393,0.7841840310190734,0.2055167698607001,-0.1905472446215371,-0.13545318694325917,-0.17214318056581754,1.8832252764522284
| 2,812
|
Process utilizing autophagic mechanism
| 36
| 137
| 2.497149
| 0.01252
|
Q9Y487,Q8IXJ6,Q9UII2,P07602,O14681,P30536,Q9Y2S7,P16615,P42858,P21796,P51809,O15269,P09601,Q86VR2,Q9Y5X3,Q9UNH7,Q8NHS3,P61421,P04792,P52789,Q93050,Q96HY6,P04062,O15118,O75844,P36543,Q9Y5K8,Q9Y263,Q92889,Q96GC9,Q9NZJ7,Q86UE4,Q99623,P10619,Q07820,Q8TEY7
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
3,131,394,132,266,14,408,144,275,23,397,151,37,293,167,431,41,424,420,307,53,309,55,56,57,313,327,325,322,122,98,243,248,245,251,389
|
2150,465,1677,266,584,1632,56,151,717,2604,475,1486,2656,1882,57,2390,623,739,565,55,1310,1399,420,487,1921,132,1155,2287,1736,1351,37,245,1850,864,144,1113,1923,1195,1114,2674,694,674,23,2210,14,313,1314,2788,1119,275,1451,1856,397,307,1124,932,1241,2729,424,1548,538,2292,1209,1551,1936,1322,251,1166,1864,1249,1555,1704,778,2396,683,2617,941,1292,1255,1613,243,293,439,131,1137,41,389,2692,1464,1064,322,53,2178,2450,2021,122,1024,309,1988,2139,2304,248,2560,944,595,2029,2141,836,2142,2705,1384,990,2526,98,2033,2565,1303,1957,787,394,1030,1183,1577,431,668,1304,1809,325,689,1811,408,1387,2590,3,327,167,900
|
-0.471476648351972,0.49962950681326135,-0.2459980349044931,0.9473814090258249,0.34515985407120203,-0.22747447582986668,2.916446962695746,1.617013061048013,0.22309537077734548,-0.8611490148593872,0.48260039141735633,-0.17214318056581754,-0.9816645976999411,-0.33922324092093464,2.8772408406430023,-0.6251920440620977,0.31045870212056503,0.2055167698607001,0.37972336891623004,2.9684696908889308,-0.0989194316256046,-0.13545318694325917,0.5674169318211052,0.46553808003374114,-0.35799118461648044,1.7510917082093325,-0.026314622385095934,-0.5479853796195989,-0.2645618200989318,-0.11716687434726772,3.4735930042919643,1.0278684187598215,-0.3204965379073243,0.11708504290317308,1.6768478836617977,-0.008258738440055532,-0.35799118461648044,-0.044408450650093925,-0.008258738440055532,-1.0222261408317312,0.24063844353304098,0.2581461514602102,4.127427393456283,-0.5096446720406466,4.433024287479104,0.7841840310190734,-0.0989194316256046,-2.1771642860934013,-0.008258738440055532,0.9149813991987668,-0.15377855875444413,-0.3204965379073243,0.6011152406986369,0.8170649925871301,-0.008258738440055532,0.08145780404230812,-0.06254040557376016,-1.2280559205447314,0.5674169318211052,-0.1905472446215371,0.4141504853427531,-0.5479853796195989,-0.044408450650093925,-0.1905472446215371,-0.35799118461648044,-0.0989194316256046,1.0118291637604662,-0.026314622385095934,-0.3204965379073243,-0.06254040557376016,-0.1905472446215371,-0.2459980349044931,0.18790247626968237,-0.6251920440620977,0.2581461514602102,-0.8811147225178695,0.08145780404230812,-0.0807106708667228,-0.06254040557376016,-0.2089909446401189,1.043878838847843,0.8498241944386672,0.5505191412386632,1.7658680852573057,-0.008258738440055532,3.349799142139882,0.6179160419293773,-1.062986143976836,-0.15377855875444413,0.027739919068620857,0.7676975668159858,3.0459708542969364,-0.471476648351972,-0.664061673412729,-0.3956516265185736,1.8686378297720425,0.04568305057423946,0.8170649925871301,-0.3768005767007224,-0.45245684076640463,-0.5479853796195989,1.0278684187598215,-0.7817584262207112,0.08145780404230812,0.34515985407120203,-0.3956516265185736,-0.45245684076640463,0.15256614703595497,-0.45245684076640463,-1.1039468355518776,-0.11716687434726772,0.06358895367080376,-0.7423429355985278,2.226542769012561,-0.3956516265185736,-0.7817584262207112,-0.0807106708667228,-0.35799118461648044,0.18790247626968237,0.6179160419293773,0.04568305057423946,-0.026314622385095934,-0.1905472446215371,0.5674169318211052,0.2756186567217988,-0.0807106708667228,-0.283166031185393,0.7676975668159858,0.2581461514602102,-0.283166031185393,0.6011152406986369,-0.11716687434726772,-0.8213597823323313,5.214962353364934,0.7676975668159858,1.5113424450941435,0.11708504290317308
| 2,812
|
Abnormal circulating cholesterol concentration
| 12
| 29
| 2.493385
| 0.012653
|
Q15800,O75431,Q9NZJ7,P07602,P37268,Q14739,Q8N511,Q9NVI7,P42858,Q15392,P06737,P02545
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
129,65,98,132,38,235,12,273,275,150,372,371
|
65,371,372,132,2754,38,275,816,533,748,655,2509,1603,2341,2629,235,150,657,129,1418,2057,12,1903,1226,1227,273,98,857,430
|
2.6920877924017246,0.6346847947097649,0.6346847947097649,1.7510917082093325,-1.4391379895738585,3.4735930042919643,0.9149813991987668,0.15256614703595497,0.4141504853427531,0.2055167698607001,0.2756186567217988,-0.7423429355985278,-0.2089909446401189,-0.5865005631893707,-0.9011281689088609,1.0917382653656786,1.6469797626441487,0.2756186567217988,1.780620541054555,-0.13545318694325917,-0.41454454507068694,4.466400716267569,-0.33922324092093464,-0.044408450650093925,-0.044408450650093925,0.9311961834886229,2.226542769012561,0.13484377635600422,0.5674169318211052
| 2,812
|
Porphyrin and chlorophyll metabolism
| 6
| 12
| 2.48726
| 0.012873
|
P09601,P36551,Q7KZN9,Q5JPH6,P22830,P30519
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
37,197,133,305,126,31
|
2286,354,1112,37,126,1044,31,197,1122,472,305,133
|
-0.5479853796195989,0.6848001484363205,-0.008258738440055532,3.4735930042919643,1.8247352597370783,0.027739919068620857,3.80008400175991,1.280653405466914,-0.008258738440055532,0.49962950681326135,0.8334597491992295,1.7510917082093325
| 2,812
|
Abnormal biliary tract morphology
| 10
| 21
| 2.484504
| 0.012973
|
Q9NZJ7,P07602,P09601,Q92889,Q10713,Q14739,Q5XKP0,O43681,P04062,Q14108
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
98,132,37,322,138,235,212,182,55,62
|
182,371,55,132,37,638,1689,1641,471,138,62,235,212,322,1619,2303,948,98,2671,1810,2387
|
1.373639236931527,0.6346847947097649,2.9684696908889308,1.7510917082093325,3.4735930042919643,0.2930561203226198,-0.2459980349044931,-0.22747447582986668,0.49962950681326135,1.7362913212685769,2.7453620538410717,1.0917382653656786,1.186694264872841,0.7676975668159858,-0.2089909446401189,-0.5479853796195989,0.08145780404230812,2.226542769012561,-1.0019206995296568,-0.283166031185393,-0.6058241514720926
| 2,812
|
Bulbar signs
| 6
| 11
| 2.48363
| 0.013005
|
Q9NZJ7,P07602,P03886,Q99720,O43681,P04062
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
98,132,100,135,182,55
|
182,100,55,1036,132,744,1786,1618,135,98,325
|
1.373639236931527,2.1984168906874886,2.9684696908889308,0.027739919068620857,1.7510917082093325,0.2055167698607001,-0.283166031185393,-0.2089909446401189,1.7510917082093325,2.226542769012561,0.7676975668159858
| 2,812
|
Organophosphate ester transport
| 14
| 23
| 2.482749
| 0.013037
|
P33527,Q8WTV0,P12236,P08183,Q6NUK1,Q4KMQ2,Q8TB61,Q9H2D1,P22307,P05141,Q96GC9,Q9HC21,Q9BZF1,Q14108
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
411,67,261,71,387,522,79,48,551,487,122,350,349,62
|
586,487,71,864,261,2409,551,411,817,2509,1130,62,522,387,1255,1947,79,67,122,349,48,350,2204
|
0.34515985407120203,0.46553808003374114,2.665336704465738,0.11708504290317308,0.9635371984080219,-0.6446044732945461,0.3969539001942955,0.5842822509907212,0.15256614703595497,-0.7423429355985278,-0.008258738440055532,2.7453620538410717,0.4313132764939044,0.6179160419293773,-0.06254040557376016,-0.35799118461648044,2.489563986964071,2.678721796351966,1.8686378297720425,0.7014420888364408,3.110074180270112,0.7014420888364408,-0.490539185592664
| 2,812
|
Visual field defect
| 10
| 41
| 2.480489
| 0.01312
|
Q9Y287,P03886,P01889,Q8NHS3,Q969G3,P04439,Q8WWV3,O75381,P40855,Q9H061
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
193,100,201,41,268,204,16,145,345,30
|
1529,465,2246,1151,343,477,145,623,590,201,100,2507,204,1780,1238,1443,2252,1925,1088,345,1361,1596,1857,1975,2128,521,779,729,2445,1254,41,882,16,1516,268,1102,2230,1470,30,2464,193
|
-0.1905472446215371,0.49962950681326135,-0.5287933290146903,-0.026314622385095934,0.7014420888364408,0.48260039141735633,1.661926099494074,0.31045870212056503,0.34515985407120203,1.2494429822888136,2.1984168906874886,-0.7423429355985278,1.218123559434321,-0.283166031185393,-0.06254040557376016,-0.15377855875444413,-0.5287933290146903,-0.35799118461648044,0.009759382165723819,0.7014420888364408,-0.11716687434726772,-0.2089909446401189,-0.3204965379073243,-0.3768005767007224,-0.45245684076640463,0.4313132764939044,0.18790247626968237,0.22309537077734548,-0.664061673412729,-0.06254040557376016,3.349799142139882,0.11708504290317308,4.309667504674183,-0.17214318056581754,0.9473814090258249,0.009759382165723819,-0.5096446720406466,-0.15377855875444413,3.8356886250962248,-0.6835638805894443,1.3272665469737428
| 2,812
|
Decreased activity of mitochondrial complex i
| 7
| 27
| 2.479688
| 0.01315
|
O96000,P03886,Q70HW3,Q9H845,Q9Y6M9,O43676,Q9UBX3
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
225,100,5,265,231,10,59
|
10,1276,477,1306,587,597,225,100,2084,1971,1642,578,2008,305,2445,5,417,2302,461,1664,1223,265,1525,59,993,1482,231
|
4.761828046714546,-0.0807106708667228,0.48260039141735633,-0.0989194316256046,0.34515985407120203,0.3278265608377056,1.1393423790368928,2.1984168906874886,-0.4334795450313125,-0.3768005767007224,-0.22747447582986668,0.3624587383041505,-0.3956516265185736,0.8334597491992295,-0.664061673412729,5.017262595389153,0.5842822509907212,-0.5479853796195989,0.5166255731433357,-0.22747447582986668,-0.044408450650093925,0.9635371984080219,-0.17214318056581754,2.8641358146662417,0.06358895367080376,-0.15377855875444413,1.1235025176038205
| 2,812
|
Cardiac muscle contraction
| 9
| 23
| 2.477526
| 0.01323
|
Q9UDW1,O14949,P09493,P14406,P16615,P13073,P47985,P05023,P22695
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
64,70,319,28,144,146,147,184,250
|
70,590,184,467,1036,723,319,844,1156,146,28,344,966,144,673,250,605,147,2652,1697,479,2601,64
|
2.665336704465738,0.34515985407120203,1.3582082159271402,0.49962950681326135,0.027739919068620857,0.22309537077734548,0.7676975668159858,0.13484377635600422,-0.026314622385095934,1.661926099494074,3.941725005389792,0.7014420888364408,0.06358895367080376,1.6768478836617977,0.2581461514602102,1.0118291637604662,0.3278265608377056,1.661926099494074,-0.9614575627830952,-0.2459980349044931,0.48260039141735633,-0.8412307870350623,2.732071824115165
| 2,812
|
Ascites
| 7
| 23
| 2.47415
| 0.013355
|
Q92889,P08236,Q14739,Q13510,P04062,O15118,Q14108
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
322,354,235,85,55,56,62
|
56,995,1881,1309,55,354,1037,1039,1404,471,2509,1054,1601,377,1455,1746,85,62,235,1096,322,948,2387
|
2.916446962695746,0.04568305057423946,-0.33922324092093464,-0.0989194316256046,2.9684696908889308,0.6848001484363205,0.027739919068620857,0.027739919068620857,-0.13545318694325917,0.49962950681326135,-0.7423429355985278,0.027739919068620857,-0.2089909446401189,0.6346847947097649,-0.15377855875444413,-0.2645618200989318,2.393526363136978,2.7453620538410717,1.0917382653656786,0.009759382165723819,0.7676975668159858,0.08145780404230812,-0.6058241514720926
| 2,812
|
Progressive neurologic deterioration
| 9
| 19
| 2.466887
| 0.013629
|
P16278,Q9Y287,Q9NZJ7,P07602,Q10713,Q5XKP0,O43681,P04062,P54802
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
256,193,98,132,138,212,182,55,152
|
182,55,132,2332,256,1442,410,2252,2087,152,332,932,138,1374,212,2053,1989,98,193
|
1.373639236931527,2.9684696908889308,1.7510917082093325,-0.5865005631893707,0.995760955144229,-0.15377855875444413,0.5842822509907212,-0.5287933290146903,-0.4334795450313125,1.617013061048013,0.7346320169701449,0.08145780404230812,1.7362913212685769,-0.11716687434726772,1.186694264872841,-0.41454454507068694,-0.3768005767007224,2.226542769012561,1.3272665469737428
| 2,812
|
Lipoprotein metabolic process
| 6
| 14
| 2.454734
| 0.014099
|
O75608,Q9NUJ1,Q8N2K0,P04062,Q9BQE5,P50897
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
33,254,247,55,26,95
|
336,1234,33,55,2592,95,778,247,756,1465,617,26,2141,254
|
0.7180526668602384,-0.06254040557376016,3.75240658285758,2.9684696908889308,-0.8412307870350623,2.226542769012561,0.18790247626968237,1.0278684187598215,0.2055167698607001,-0.15377855875444413,0.3278265608377056,4.069774341527857,-0.45245684076640463,1.0118291637604662
| 2,812
|
Protein transmembrane import into intracellular organelle
| 6
| 12
| 2.453423
| 0.01415
|
O60830,Q99595,O75381,Q15388,O95831,O14925
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
0,1,145,348,158,255
|
255,383,0,145,528,158,768,1401,348,704,1,785
|
0.995760955144229,0.6179160419293773,5.214962353364934,1.661926099494074,0.4141504853427531,1.5567809266545096,0.18790247626968237,-0.13545318694325917,0.7014420888364408,0.24063844353304098,5.214962353364934,0.18790247626968237
| 2,812
|
Subsets and Splits
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