term
stringlengths
2
121
overlap
int64
6
281
setsize
int64
7
499
score
float64
1.96
10.6
pval
float64
0
0.05
edge
stringlengths
41
1.97k
type
stringclasses
5 values
subtype
stringclasses
24 values
subtype_key
stringclasses
24 values
edge_idxs
stringlengths
11
1.17k
ann_idxs
stringlengths
19
2.31k
ann_vals
stringlengths
124
9.94k
sig_size
int64
2.2k
3.73k
Zinc finger, RING-type, conserved site [IPR017907]
10
14
2.322455
0.020208
O95376,O15344,Q99496,Q9H000,Q99590,Q14258,Q96T88,P19474,Q9UPN9,Q5VTR2
Sequence
InterPro Conserved site
interpro_conserved_site
90,304,573,235,198,338,726,85,652,95
1930,304,1557,90,85,338,719,95,726,573,198,235,1542,652
-0.2380779229637603,0.7456315061409986,-0.056227562452395775,1.4399830962547482,1.5356967553836633,0.7143997644606782,0.37285959438321625,1.4399830962547482,0.37285959438321625,0.4966235150833113,0.9965422799663923,0.9022328809207614,-0.025796646179977383,0.4346787153903801
2,808
Nucleosome organization
23
53
2.316775
0.020516
Q9H7B4,P62805,P16403,P51532,O75367,Q96GM5,P06748,Q969G3,Q99733,P33993,Q9NRL2,P17096,P49711,Q8WXX5,Q96T23,Q9P0M6,Q12824,P55209,P07305,Q9BQ67,Q9BYW2,Q15020,Q6ZRS2
Processes and pathways
GO Biological process
msigdb_gobp
5,629,503,509,403,166,662,50,57,550,202,437,439,478,725,617,207,93,587,234,529,637,254
1267,808,403,2065,662,587,2146,1808,709,503,437,866,1219,550,1417,439,1287,509,93,629,2039,876,207,1295,1102,1162,2617,637,1364,254,1720,840,1372,478,1967,955,1857,50,166,725,57,234,2131,529,2758,5,2313,202,617,1923,1204,1265,1266
0.06570166634344686,0.31116761353809186,0.6208844836851677,-0.32851996753944923,0.40375335457087713,0.46563549531765897,-0.38863123561707724,-0.17760269665740328,0.37285959438321625,0.5276425976297412,0.5897732536440574,0.28036976760383425,0.09626890734001688,0.4966235150833113,0.004668675743301722,0.5897732536440574,0.06570166634344686,0.5276425976297412,1.4399830962547482,0.4346787153903801,-0.298409052876078,0.28036976760383425,0.9650771179059916,0.06570166634344686,0.157503833136453,0.12686969850312335,-1.0976762202817745,0.4346787153903801,0.035168185019498165,0.8395044242627464,-0.1169852894996316,0.31116761353809186,0.035168185019498165,0.558692568069395,-0.2380779229637603,0.24960427184179984,-0.17760269665740328,2.0824413152506027,1.0911081847929223,0.37285959438321625,1.9208805629344818,0.9022328809207614,-0.35859411376495665,0.5276425976297412,-2.201975058706754,5.772234941394142,-0.5382522425398498,0.9965422799663923,0.46563549531765897,-0.2078582008305619,0.12686969850312335,0.09626890734001688,0.09626890734001688
2,808
Basal transcription machinery binding
6
26
2.310014
0.020887
Q15061,Q9H7B4,Q9NQG5,Q5BKZ1,Q92889,O60869
Functions
GO Molecular function
msigdb_gomf
251,5,214,112,119,115
115,1933,1213,1024,626,289,470,680,251,112,1043,561,1237,2186,1241,840,119,1673,1674,5,2274,214,653,1923,1204,907
1.2809941384574963,-0.2380779229637603,0.09626890734001688,0.18817110729581882,0.4346787153903801,0.7768929689687475,0.558692568069395,0.40375335457087713,0.8395044242627464,1.312737953942776,0.18817110729581882,0.4966235150833113,0.09626890734001688,-0.41863107325011994,0.09626890734001688,0.31116761353809186,1.2809941384574963,-0.08662385171865596,-0.08662385171865596,5.772234941394142,-0.5084042217553665,0.9650771179059916,0.4346787153903801,-0.2078582008305619,0.12686969850312335,0.28036976760383425
2,808
Chromatin assembly or disassembly
34
72
2.299621
0.02147
Q13547,Q9H7B4,Q13363,P62805,P16403,P51532,Q15047,O75367,Q96GM5,Q8N7H5,P06748,Q969G3,P52926,O94776,Q9Y3T9,Q99733,P33993,Q9NRL2,P17096,O60264,P49711,O60341,O95983,Q8WXX5,Q96T23,Q9P0M6,Q12824,P16402,P55209,P07305,Q9BQ67,Q96EB6,Q9UK61,Q15020
Processes and pathways
GO Biological process
msigdb_gobp
516,5,135,629,503,509,834,403,166,840,662,50,52,541,852,57,550,202,437,808,439,809,75,478,725,617,207,709,93,587,234,789,262,637
1135,1267,2316,2060,808,809,403,541,75,1213,662,587,2146,1142,1808,709,503,437,1342,866,1027,1219,550,1417,439,1287,509,826,52,93,629,2039,876,207,1102,1162,1510,1426,135,516,637,834,1364,1301,2186,2307,840,1372,1855,478,1967,955,1857,50,789,166,1191,725,2128,57,234,2093,2758,5,2313,202,1612,617,262,852,1265,2024
0.12686969850312335,0.06570166634344686,-0.5680616178685269,-0.32851996753944923,0.31116761353809186,0.31116761353809186,0.6208844836851677,0.4966235150833113,1.663681686992128,0.09626890734001688,0.40375335457087713,0.46563549531765897,-0.38863123561707724,0.12686969850312335,-0.17760269665740328,0.37285959438321625,0.5276425976297412,0.5897732536440574,0.035168185019498165,0.28036976760383425,0.18817110729581882,0.09626890734001688,0.4966235150833113,0.004668675743301722,0.5897732536440574,0.06570166634344686,0.5276425976297412,0.31116761353809186,2.017743302585445,1.4399830962547482,0.4346787153903801,-0.298409052876078,0.28036976760383425,0.9650771179059916,0.157503833136453,0.12686969850312335,-0.025796646179977383,0.004668675743301722,1.185926720770312,0.5276425976297412,0.4346787153903801,0.31116761353809186,0.035168185019498165,0.06570166634344686,-0.41863107325011994,-0.5382522425398498,0.31116761353809186,0.035168185019498165,-0.17760269665740328,0.558692568069395,-0.2380779229637603,0.24960427184179984,-0.17760269665740328,2.0824413152506027,0.34199761865011447,1.0911081847929223,0.12686969850312335,0.37285959438321625,-0.35859411376495665,1.9208805629344818,0.9022328809207614,-0.32851996753944923,-2.201975058706754,5.772234941394142,-0.5382522425398498,0.9965422799663923,-0.056227562452395775,0.46563549531765897,0.8395044242627464,0.31116761353809186,0.09626890734001688,-0.268261621890122
2,808
Positive regulation of rna splicing
13
22
2.298292
0.021545
Q13243,Q14011,P98179,P38159,P26368,P08621,Q09161,Q13595,Q9UMS4,Q15427,P24928,P62995,Q9Y2W1
Processes and pathways
GO Biological process
msigdb_gobp
134,70,596,106,284,383,365,271,650,600,329,122,535
912,383,1022,710,329,284,1147,106,1821,122,596,365,134,633,271,70,600,1672,2127,1010,650,535
0.24960427184179984,0.6520260895751347,0.18817110729581882,0.37285959438321625,0.7143997644606782,0.7768929689687475,0.12686969850312335,1.3445088870289958,-0.17760269665740328,1.2492775721878775,0.46563549531765897,0.683197904709607,1.185926720770312,0.4346787153903801,0.8081839940334757,1.6957426054920703,0.46563549531765897,-0.08662385171865596,-0.35859411376495665,0.21887131973311785,0.4346787153903801,0.5276425976297412
2,808
Viral transcription
10
14
2.284879
0.02232
Q13547,O94992,Q08211,Q13573,Q14684,P52926,Q12824,P51532,O14646,P19474
Processes and pathways
GO Biological process
msigdb_gobp
516,248,470,633,162,52,207,509,326,85
326,248,1566,85,509,52,470,207,1163,516,633,162,883,725
0.7143997644606782,0.8395044242627464,-0.056227562452395775,1.5356967553836633,0.5276425976297412,2.017743302585445,0.558692568069395,0.9650771179059916,0.12686969850312335,0.5276425976297412,0.4346787153903801,1.0911081847929223,0.28036976760383425,0.37285959438321625
2,808
Transcription corepressor activity
24
46
2.279056
0.022664
Q9UQ80,Q13547,Q13363,Q13573,O14776,P51532,P25685,Q96IZ0,Q00839,P56545,P52926,Q9HCD5,O94776,Q9Y3T9,O75381,Q07021,Q9BQG0,P27695,Q9ULU4,P51608,P80723,Q9H1B7,Q96EB6,Q9BQ70
Functions
GO Molecular function
msigdb_gomf
801,516,135,633,492,509,759,569,289,407,52,191,541,852,433,312,346,820,739,826,218,120,789,126
1548,1072,492,433,541,1630,1564,759,820,2255,509,826,1496,52,407,1422,218,289,312,1426,1166,135,516,633,1108,2006,1438,1523,953,789,569,1191,1004,1058,2677,126,346,120,191,1681,903,1263,739,801,1923,852
-0.056227562452395775,0.157503833136453,0.5276425976297412,0.5897732536440574,0.4966235150833113,-0.08662385171865596,-0.056227562452395775,0.34199761865011447,0.31116761353809186,-0.5084042217553665,0.5276425976297412,0.31116761353809186,-0.025796646179977383,2.017743302585445,0.6208844836851677,0.004668675743301722,0.9336406021056348,0.7768929689687475,0.7456315061409986,0.004668675743301722,0.12686969850312335,1.185926720770312,0.5276425976297412,0.4346787153903801,0.157503833136453,-0.268261621890122,0.004668675743301722,-0.025796646179977383,0.24960427184179984,0.34199761865011447,0.4966235150833113,0.12686969850312335,0.21887131973311785,0.18817110729581882,-1.386047238947879,1.2492775721878775,0.7143997644606782,1.2809941384574963,1.0280359415852773,-0.08662385171865596,0.28036976760383425,0.09626890734001688,0.37285959438321625,0.34199761865011447,-0.2078582008305619,0.31116761353809186
2,808
Positive regulation of mrna splicing via spliceosome
11
17
2.276261
0.02283
Q14011,P98179,P38159,Q13573,P08621,Q09161,Q13595,Q9UMS4,Q15427,P62995,Q9Y2W1
Processes and pathways
GO Biological process
msigdb_gobp
70,596,106,633,383,365,271,650,600,122,535
383,1022,710,1147,106,1821,122,596,365,633,271,70,600,1672,2127,650,535
0.6520260895751347,0.18817110729581882,0.37285959438321625,0.12686969850312335,1.3445088870289958,-0.17760269665740328,1.2492775721878775,0.46563549531765897,0.683197904709607,0.4346787153903801,0.8081839940334757,1.6957426054920703,0.46563549531765897,-0.08662385171865596,-0.35859411376495665,0.4346787153903801,0.5276425976297412
2,808
Zinc finger, RING/FYVE/PHD-type [IPR013083]
28
48
2.276173
0.022836
Q53GS9,Q03164,Q7Z3T8,Q99496,O96028,Q14139,Q5W0B1,O95696,P45974,P29375,Q8TEY7,O15344,Q9NRL2,Q99590,Q9UIG0,Q9ULU4,Q14258,Q96T23,Q96T88,P19474,Q5VTR2,O95376,Q9H000,Q9Y4X5,Q9UMS4,Q9UPN9,Q14839,Q9BTC0
Sequence
InterPro Superfamily
interpro_homologous_superfamily
684,151,563,573,282,411,175,542,551,181,65,304,202,198,738,739,338,725,726,85,95,90,235,378,650,652,636,398
1464,1930,304,1557,2175,90,542,282,85,181,551,151,1295,2352,1426,411,338,719,636,2649,684,95,175,2468,563,2383,887,65,2011,1003,725,726,573,198,398,235,202,2019,1542,1921,738,739,650,2136,652,2581,2526,378
-0.025796646179977383,-0.2380779229637603,0.7456315061409986,-0.056227562452395775,-0.41863107325011994,1.4399830962547482,0.4966235150833113,0.7768929689687475,1.5356967553836633,1.0280359415852773,0.4966235150833113,1.12268648099708,0.06570166634344686,-0.5978320623763692,0.004668675743301722,0.6208844836851677,0.7143997644606782,0.37285959438321625,0.4346787153903801,-1.271178845692474,0.40375335457087713,1.4399830962547482,1.0595579576867387,-0.7460900042688136,0.4966235150833113,-0.6275632860710119,0.28036976760383425,1.7920787382883043,-0.268261621890122,0.21887131973311785,0.37285959438321625,0.37285959438321625,0.4966235150833113,0.9965422799663923,0.6520260895751347,0.9022328809207614,0.9965422799663923,-0.268261621890122,-0.025796646179977383,-0.2078582008305619,0.37285959438321625,0.37285959438321625,0.4346787153903801,-0.35859411376495665,0.4346787153903801,-0.981166329813051,-0.8639647040355153,0.683197904709607
2,808
Clinodactyly
36
118
2.268608
0.023292
Q96S52,Q8WWQ0,Q6ZRS2,Q06124,P51532,P42858,Q03164,P51812,P60953,O75367,Q96GM5,Q05086,Q6DKJ4,P08069,Q969G3,P52926,Q96PZ0,P02545,Q9Y619,Q6KC79,Q8NFH4,P49711,O60216,Q9Y4R8,Q12824,Q15427,Q53EZ4,Q93008,P27635,Q02750,Q15022,Q92889,P21281,P55011,Q03252,Q9Y4P3
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
397,395,254,15,509,24,151,148,408,403,166,410,560,546,50,52,53,544,323,446,606,439,74,350,207,600,94,373,228,109,518,119,357,361,363,536
1546,1463,1267,2513,1552,1467,1469,74,809,2100,1800,2731,403,1686,1689,2065,544,546,1985,920,2529,2418,2460,357,1340,1811,228,867,1221,2324,924,1028,24,2692,1350,1641,439,509,826,1419,148,52,361,593,408,1355,1093,674,109,151,363,410,15,1037,1038,2262,207,1295,2464,634,1771,1772,1430,832,518,2377,1515,600,1109,94,2265,1182,1303,560,446,1438,254,2469,1240,2560,2667,2662,1665,606,1372,783,395,119,1726,373,1119,50,1380,166,1781,1054,53,397,1191,1004,1447,2358,2272,1916,2165,800,1921,2020,738,1737,1203,1457,1926,853,536,350,1070,323
-0.056227562452395775,-0.025796646179977383,0.06570166634344686,-0.8639647040355153,-0.056227562452395775,-0.025796646179977383,-0.025796646179977383,1.663681686992128,0.31116761353809186,-0.35859411376495665,-0.17760269665740328,-1.8957417635481726,0.6208844836851677,-0.1169852894996316,-0.1169852894996316,-0.32851996753944923,0.4966235150833113,0.4966235150833113,-0.268261621890122,0.24960427184179984,-0.8933290661726461,-0.686906887210775,-0.7460900042688136,0.683197904709607,0.035168185019498165,-0.17760269665740328,0.9022328809207614,0.28036976760383425,0.09626890734001688,-0.5680616178685269,0.24960427184179984,0.18817110729581882,2.8661831768006865,-1.5287783284330163,0.035168185019498165,-0.08662385171865596,0.5897732536440574,0.5276425976297412,0.31116761353809186,0.004668675743301722,1.12268648099708,2.017743302585445,0.683197904709607,0.46563549531765897,0.6208844836851677,0.035168185019498165,0.157503833136453,0.40375335457087713,1.3445088870289958,1.12268648099708,0.683197904709607,0.6208844836851677,3.6292428778432244,0.18817110729581882,0.18817110729581882,-0.5084042217553665,0.9650771179059916,0.06570166634344686,-0.7460900042688136,0.4346787153903801,-0.14731164812392894,-0.14731164812392894,0.004668675743301722,0.31116761353809186,0.5276425976297412,-0.6275632860710119,-0.025796646179977383,0.46563549531765897,0.157503833136453,1.4399830962547482,-0.5084042217553665,0.12686969850312335,0.06570166634344686,0.4966235150833113,0.5897732536440574,0.004668675743301722,0.8395044242627464,-0.7460900042688136,0.09626890734001688,-0.9519302317950293,-1.357388264627863,-1.3286908083244282,-0.08662385171865596,0.46563549531765897,0.035168185019498165,0.34199761865011447,0.6520260895751347,1.2809941384574963,-0.1169852894996316,0.683197904709607,0.157503833136453,2.0824413152506027,0.035168185019498165,1.0911081847929223,-0.14731164812392894,0.18817110729581882,2.017743302585445,0.6520260895751347,0.12686969850312335,0.21887131973311785,0.004668675743301722,-0.5978320623763692,-0.5084042217553665,-0.2078582008305619,-0.38863123561707724,0.34199761865011447,-0.2078582008305619,-0.268261621890122,0.37285959438321625,-0.1169852894996316,0.12686969850312335,0.004668675743301722,-0.2078582008305619,0.31116761353809186,0.5276425976297412,0.7143997644606782,0.18817110729581882,0.7456315061409986
2,808
Abnormal oral physiology
12
53
2.267906
0.023335
Q93008,Q15165,Q92804,Q13501,P55795,P43243,Q6UN15,P50995,P01889,P55011,P35637,P51812
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
373,2,38,136,195,286,210,358,23,361,182,148
2343,2100,1979,23,662,1935,2417,2030,499,1080,1339,2735,2324,870,182,2371,928,286,764,358,826,1419,148,361,1764,195,1584,1767,363,410,1163,2183,136,1513,1171,1957,878,2,1515,210,1438,2662,2270,38,373,1004,2160,2358,1384,2550,1455,2096,2199
-0.5978320623763692,-0.35859411376495665,-0.268261621890122,2.8661831768006865,0.40375335457087713,-0.2380779229637603,-0.686906887210775,-0.298409052876078,0.5276425976297412,0.157503833136453,0.035168185019498165,-1.9516992342127442,-0.5680616178685269,0.28036976760383425,1.0280359415852773,-0.6275632860710119,0.24960427184179984,0.7768929689687475,0.34199761865011447,0.683197904709607,0.31116761353809186,0.004668675743301722,1.12268648099708,0.683197904709607,-0.14731164812392894,0.9965422799663923,-0.056227562452395775,-0.14731164812392894,0.683197904709607,0.6208844836851677,0.12686969850312335,-0.41863107325011994,1.185926720770312,-0.025796646179977383,0.12686969850312335,-0.2380779229637603,0.28036976760383425,8.624354780633901,-0.025796646179977383,0.9650771179059916,0.004668675743301722,-1.3286908083244282,-0.5084042217553665,2.3747748432232223,0.683197904709607,0.21887131973311785,-0.38863123561707724,-0.5978320623763692,0.035168185019498165,-0.922651025281217,0.004668675743301722,-0.32851996753944923,-0.41863107325011994
2,808
Abnormality of the uterus
16
49
2.263616
0.023598
Q8WWQ0,Q8IY37,O96028,Q13363,O60216,Q92766,O96017,Q16740,Q9BZH6,Q15437,Q92889,Q15427,O75616,P07954,Q6KC79,P51812
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
395,605,282,135,74,565,110,46,612,111,119,600,354,545,446,148
1877,1552,74,1800,354,2569,110,282,1213,545,1339,1141,1937,921,2032,1408,1221,871,2073,148,1290,1498,593,2180,1358,1094,1037,135,832,1958,600,111,46,1303,446,1237,1853,605,395,565,119,841,1447,612,2165,800,2220,1203,1070
-0.2078582008305619,-0.056227562452395775,1.663681686992128,-0.17760269665740328,0.683197904709607,-0.981166329813051,1.312737953942776,0.7768929689687475,0.09626890734001688,0.4966235150833113,0.035168185019498165,0.12686969850312335,-0.2380779229637603,0.24960427184179984,-0.298409052876078,0.004668675743301722,0.09626890734001688,0.28036976760383425,-0.32851996753944923,1.12268648099708,0.06570166634344686,-0.025796646179977383,0.46563549531765897,-0.41863107325011994,0.035168185019498165,0.157503833136453,0.18817110729581882,1.185926720770312,0.31116761353809186,-0.2380779229637603,0.46563549531765897,1.312737953942776,2.1796705270663246,0.06570166634344686,0.5897732536440574,0.09626890734001688,-0.17760269665740328,0.46563549531765897,0.6520260895751347,0.4966235150833113,1.2809941384574963,0.31116761353809186,0.004668675743301722,0.46563549531765897,-0.38863123561707724,0.34199761865011447,-0.448593362815423,0.12686969850312335,0.18817110729581882
2,808
Promoter specific chromatin binding
15
22
2.262057
0.023694
Q9P2D1,Q13547,O60341,Q00839,O75367,Q15047,Q08211,Q15022,P19447,P17844,Q92889,Q96EB6,P24928,Q6KC79,P35269
Functions
GO Molecular function
msigdb_gomf
800,516,809,289,403,834,470,518,267,665,119,789,329,446,626
809,403,1213,665,267,329,1027,626,1150,826,1821,289,470,1426,516,518,834,446,1308,119,789,800
0.31116761353809186,0.6208844836851677,0.09626890734001688,0.40375335457087713,0.8081839940334757,0.7143997644606782,0.18817110729581882,0.4346787153903801,0.12686969850312335,0.31116761353809186,-0.17760269665740328,0.7768929689687475,0.558692568069395,0.004668675743301722,0.5276425976297412,0.5276425976297412,0.31116761353809186,0.5897732536440574,0.06570166634344686,1.2809941384574963,0.34199761865011447,0.34199761865011447
2,808
Histone modification
47
132
2.258093
0.02394
Q13547,Q9H7B4,Q13363,Q13573,Q13620,Q9NWY4,Q99986,P16403,Q03164,Q9P275,Q96PK6,Q99496,O96028,O75367,O94776,O95696,P52926,P02545,Q96FW1,Q6KC79,P29375,Q9ULX6,Q96ST2,Q86X55,Q9Y3Y2,Q6UXN9,P49711,O95983,Q9H4L7,O43823,Q86UY6,Q12824,Q9NW82,Q8WXI9,Q5VTR2,P18615,Q8NB78,Q86YP4,Q15014,Q15022,P61964,Q9UKN8,Q9BYW2,Q9GZS3,Q15020,Q14839,Q6ZRS2
Processes and pathways
GO Biological process
msigdb_gobp
516,5,135,633,634,14,419,503,151,428,168,573,282,403,541,542,52,544,190,446,181,62,69,341,73,197,439,75,614,78,80,207,487,225,95,464,368,524,517,518,238,649,529,530,637,636,254
1072,2316,2513,2060,78,808,809,1557,403,2437,2063,541,1745,1079,2458,542,75,2065,282,544,1213,1396,2145,2146,709,503,464,1024,982,1342,1027,181,871,2255,713,439,2106,826,1419,52,238,1505,2373,2039,1507,151,1649,207,993,1166,135,516,633,2558,634,2588,1772,636,517,637,518,834,2264,1234,2682,881,1042,1301,95,446,2467,1237,2007,2186,197,1438,254,1720,1849,1240,80,341,524,2234,2307,840,368,225,1308,1119,1309,789,190,693,168,69,1191,726,573,2014,961,419,2705,529,530,1860,614,5,1609,2195,1256,2313,487,14,428,1867,1681,2628,2277,738,1263,649,2362,62,1923,1204,2581,852,73,853,1741,2527
0.157503833136453,-0.5680616178685269,-0.8639647040355153,-0.32851996753944923,1.631646524525365,0.31116761353809186,0.31116761353809186,-0.056227562452395775,0.6208844836851677,-0.7165186604646431,-0.32851996753944923,0.4966235150833113,-0.14731164812392894,0.157503833136453,-0.7460900042688136,0.4966235150833113,1.663681686992128,-0.32851996753944923,0.7768929689687475,0.4966235150833113,0.09626890734001688,0.004668675743301722,-0.38863123561707724,-0.38863123561707724,0.37285959438321625,0.5276425976297412,0.558692568069395,0.18817110729581882,0.21887131973311785,0.035168185019498165,0.18817110729581882,1.0280359415852773,0.28036976760383425,-0.5084042217553665,0.37285959438321625,0.5897732536440574,-0.35859411376495665,0.31116761353809186,0.004668675743301722,2.017743302585445,0.8708541043895993,-0.025796646179977383,-0.6275632860710119,-0.298409052876078,-0.025796646179977383,1.12268648099708,-0.08662385171865596,0.9650771179059916,0.21887131973311785,0.12686969850312335,1.185926720770312,0.5276425976297412,0.4346787153903801,-0.9519302317950293,0.4346787153903801,-1.0103589569207994,-0.14731164812392894,0.4346787153903801,0.5276425976297412,0.4346787153903801,0.5276425976297412,0.31116761353809186,-0.5084042217553665,0.09626890734001688,-1.443251300169841,0.28036976760383425,0.18817110729581882,0.06570166634344686,1.4399830962547482,0.5897732536440574,-0.7460900042688136,0.09626890734001688,-0.268261621890122,-0.41863107325011994,0.9965422799663923,0.004668675743301722,0.8395044242627464,-0.1169852894996316,-0.17760269665740328,0.09626890734001688,1.631646524525365,0.7143997644606782,0.5276425976297412,-0.47851783636555056,-0.5382522425398498,0.31116761353809186,0.683197904709607,0.9336406021056348,0.06570166634344686,0.157503833136453,0.06570166634344686,0.34199761865011447,1.0280359415852773,0.40375335457087713,1.0911081847929223,1.7278291635665208,0.12686969850312335,0.37285959438321625,0.4966235150833113,-0.268261621890122,0.24960427184179984,0.6208844836851677,-1.5856145428378061,0.5276425976297412,0.5276425976297412,-0.17760269665740328,0.46563549531765897,5.772234941394142,-0.056227562452395775,-0.41863107325011994,0.09626890734001688,-0.5382522425398498,0.558692568069395,3.8636545071273094,0.6208844836851677,-0.17760269665740328,-0.08662385171865596,-1.1266965842029726,-0.5084042217553665,0.37285959438321625,0.09626890734001688,0.4346787153903801,-0.5978320623763692,1.8564295019872012,-0.2078582008305619,0.12686969850312335,-0.981166329813051,0.31116761353809186,1.6957426054920703,0.31116761353809186,-0.1169852894996316,-0.8639647040355153
2,808
Thin skin
7
25
2.256203
0.024058
P18074,Q13126,P19447,Q92889,P02545,Q96PU5,Q9Y619
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
406,7,267,119,544,25,323
1874,2343,2062,2063,544,1339,2248,1144,406,267,1340,1812,1347,1641,1351,1645,1161,1649,7,1238,119,1054,25,614,323
-0.2078582008305619,-0.5978320623763692,-0.32851996753944923,-0.32851996753944923,0.4966235150833113,0.035168185019498165,-0.5084042217553665,0.12686969850312335,0.6208844836851677,0.8081839940334757,0.035168185019498165,-0.17760269665740328,0.035168185019498165,-0.08662385171865596,0.035168185019498165,-0.08662385171865596,0.12686969850312335,-0.08662385171865596,5.668578356402774,0.09626890734001688,1.2809941384574963,0.18817110729581882,2.833264740413757,0.46563549531765897,0.7456315061409986
2,808
Cis regulatory region sequence specific dna binding
16
40
2.237781
0.025235
Q9Y467,Q13547,P17096,Q9H7B4,P49711,Q00839,Q08211,P53999,Q9BQG0,P38159,Q15022,P52926,O95785,O15226,Q9Y2W1,Q92766
Functions
GO Molecular function
msigdb_gomf
204,516,437,5,439,289,470,194,346,106,518,52,543,579,535,565
1072,1930,579,543,1213,622,437,1219,106,2371,1150,822,2350,439,1496,52,194,1091,289,2374,470,1295,1163,1166,516,518,945,1523,565,1309,789,726,346,2549,5,1865,800,1923,535,204
0.157503833136453,-0.2380779229637603,0.46563549531765897,0.4966235150833113,0.09626890734001688,0.4346787153903801,0.5897732536440574,0.09626890734001688,1.3445088870289958,-0.6275632860710119,0.12686969850312335,0.31116761353809186,-0.5978320623763692,0.5897732536440574,-0.025796646179977383,2.017743302585445,0.9965422799663923,0.157503833136453,0.7768929689687475,-0.6275632860710119,0.558692568069395,0.06570166634344686,0.12686969850312335,0.12686969850312335,0.5276425976297412,0.5276425976297412,0.24960427184179984,-0.025796646179977383,0.4966235150833113,0.06570166634344686,0.34199761865011447,0.37285959438321625,0.7143997644606782,-0.922651025281217,5.772234941394142,-0.17760269665740328,0.34199761865011447,-0.2078582008305619,0.5276425976297412,0.9965422799663923
2,808
Mitotic chromosome
18
36
2.236239
0.025336
Q9Y3B9,Q8TDN6,O75683,O76021,Q9H7B2,P56182,Q14692,Q14684,Q9BVP2,Q9BYG3,Q9NVP1,Q9NY93,Q9NR30,Q8IY81,Q9H6F5,Q99848,P42696,Q13601
Localization
Protein Atlas Subcellular
protein_atlas_subcellular_location_all
301,370,404,382,574,288,272,162,646,611,244,161,486,525,121,88,183,313
806,972,1270,404,382,710,183,987,288,1296,313,2118,1103,162,272,949,2331,686,1848,525,370,1726,1244,88,646,611,121,574,486,244,161,2392,968,2200,301,852
0.31116761353809186,0.21887131973311785,0.06570166634344686,0.6208844836851677,0.6520260895751347,0.37285959438321625,1.0280359415852773,0.21887131973311785,0.7768929689687475,0.06570166634344686,0.7456315061409986,-0.35859411376495665,0.157503833136453,1.0911081847929223,0.8081839940334757,0.24960427184179984,-0.5680616178685269,0.40375335457087713,-0.17760269665740328,0.5276425976297412,0.683197904709607,-0.1169852894996316,0.09626890734001688,1.5037658050599132,0.4346787153903801,0.46563549531765897,1.2809941384574963,0.4966235150833113,0.558692568069395,0.8708541043895993,1.12268648099708,-0.6275632860710119,0.24960427184179984,-0.41863107325011994,0.7768929689687475,0.31116761353809186
2,808
Melanoma
7
17
2.232348
0.025592
P11802,O96017,Q06124,Q15437,P19447,Q92889,Q9NYB0
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
283,110,15,111,267,119,399
660,110,1213,283,406,267,921,764,2148,15,111,1188,956,119,573,2194,399
0.40375335457087713,1.312737953942776,0.09626890734001688,0.7768929689687475,0.6208844836851677,0.8081839940334757,0.24960427184179984,0.34199761865011447,-0.38863123561707724,3.6292428778432244,1.312737953942776,0.12686969850312335,0.24960427184179984,1.2809941384574963,0.4966235150833113,-0.41863107325011994,0.6520260895751347
2,808
Dna integrity checkpoint signaling
9
35
2.232334
0.025593
Q6Y7W6,Q14676,O96017,Q06124,P52926,Q96RU2,Q96FV9,Q9Y619,Q9NXR7
Processes and pathways
GO Biological process
msigdb_gobp
292,366,110,15,52,157,315,323,63
2478,110,1213,2145,547,1808,1342,2073,764,52,2461,990,875,15,1296,1770,1714,679,366,1176,391,1518,292,838,1241,1668,315,1782,1910,157,528,1447,63,650,323
-0.7756206036620558,1.312737953942776,0.09626890734001688,-0.38863123561707724,0.4966235150833113,-0.17760269665740328,0.035168185019498165,-0.32851996753944923,0.34199761865011447,2.017743302585445,-0.7460900042688136,0.21887131973311785,0.28036976760383425,3.6292428778432244,0.06570166634344686,-0.14731164812392894,-0.1169852894996316,0.40375335457087713,0.683197904709607,0.12686969850312335,0.6520260895751347,-0.025796646179977383,0.7768929689687475,0.31116761353809186,0.09626890734001688,-0.08662385171865596,0.7456315061409986,-0.14731164812392894,-0.2078582008305619,1.12268648099708,0.5276425976297412,0.004668675743301722,1.8242415276513662,0.4346787153903801,0.7456315061409986
2,808
Ribosome biogenesis
97
199
2.225909
0.02602
Q567V2,O75691,Q8IWA0,Q9H7B2,Q9NX24,O15213,O60832,O60287,Q13206,Q8IY37,Q9BYG3,Q9GZR2,Q14690,Q99848,Q9H0A0,P78316,Q5JTH9,Q9BZE4,Q9UNX4,Q9Y2R4,Q8NI36,P42285,Q9Y2R9,Q9BSC4,Q13620,Q9NY93,Q9NVN8,Q9NQZ2,Q76FK4,Q92841,Q9BV38,Q9NV31,Q9UJK0,Q14978,Q9Y6V7,Q9Y5J1,Q9BXY0,O00567,Q14684,P06748,Q7Z4Q2,P55769,Q9H9Y2,Q9NV06,Q9GZL7,Q9Y2L1,Q9H501,Q9Y3A2,Q8TED0,P39019,O95478,P27635,Q15024,Q9NVP1,Q8NEF9,Q9NY61,Q9BYD6,Q9H0D6,Q15061,Q9UQ80,Q9P2D1,Q13868,Q9Y2W2,A4D1E9,Q14692,O43290,O15381,Q9Y3B9,P56182,Q7Z2Z2,Q9NQ55,Q13601,Q06265,P46087,Q07021,Q8N9T8,Q9BQG0,Q15050,P42766,P62841,Q8TDN6,Q9Y221,O75616,O76021,Q9NQT5,Q9NX58,Q9P275,Q9BVJ6,O75683,P18074,Q5RKV6,Q969X6,Q9Y4W2,Q9NR30,P05388,Q8IY81,Q9NVX2
Processes and pathways
GO Biological process
msigdb_gobp
0,497,564,574,577,538,539,51,557,605,611,613,598,88,104,595,639,647,651,654,642,627,145,143,634,161,160,159,686,691,696,699,700,680,172,703,170,655,162,662,188,672,735,203,731,741,213,742,211,711,708,228,241,244,242,260,795,257,251,801,800,773,280,745,272,264,263,301,288,314,319,313,311,308,312,343,346,339,332,335,370,377,354,382,424,425,428,420,404,406,445,479,489,486,463,525,531
745,1549,806,972,655,1207,1551,538,263,2060,264,1879,51,539,354,404,497,2505,382,708,1018,463,662,1019,814,1751,406,978,1404,1024,228,1028,711,2072,627,332,308,2292,2372,2533,672,288,2111,2259,990,1158,1953,1503,2209,2076,1706,1423,936,1226,1831,335,1832,2149,2684,1833,2586,1999,595,938,875,939,1424,2114,1955,311,312,1587,557,313,2558,634,772,773,2118,1103,1041,1169,162,598,272,680,241,339,251,2447,1111,0,947,639,445,2043,950,2305,1114,686,1662,314,1520,188,1851,2534,2333,564,605,525,2089,343,242,642,953,370,211,1242,691,1726,479,1244,2621,892,1121,1056,1248,88,346,143,696,1534,420,170,1537,1063,795,611,647,731,613,104,257,1064,213,898,1193,574,1539,735,319,1970,424,159,486,1317,1454,203,699,160,244,1386,531,1257,577,425,1065,260,161,2392,428,800,1388,2277,700,1617,2622,2168,651,801,377,2200,741,906,654,145,280,907,1872,742,1794,1928,301,2412,852,489,2490,703,172
0.34199761865011447,-0.056227562452395775,0.31116761353809186,0.21887131973311785,0.40375335457087713,0.09626890734001688,-0.056227562452395775,0.4966235150833113,0.8081839940334757,-0.32851996753944923,0.8081839940334757,-0.2078582008305619,2.017743302585445,0.4966235150833113,0.683197904709607,0.6208844836851677,0.5276425976297412,-0.8345582822732515,0.6520260895751347,0.37285959438321625,0.18817110729581882,0.558692568069395,0.40375335457087713,0.18817110729581882,0.31116761353809186,-0.14731164812392894,0.6208844836851677,0.21887131973311785,0.004668675743301722,0.18817110729581882,0.9022328809207614,0.18817110729581882,0.37285959438321625,-0.32851996753944923,0.4346787153903801,0.7143997644606782,0.7456315061409986,-0.5382522425398498,-0.6275632860710119,-0.8933290661726461,0.40375335457087713,0.7768929689687475,-0.35859411376495665,-0.5084042217553665,0.21887131973311785,0.12686969850312335,-0.2380779229637603,-0.025796646179977383,-0.448593362815423,-0.32851996753944923,-0.1169852894996316,0.004668675743301722,0.24960427184179984,0.09626890734001688,-0.17760269665740328,0.7143997644606782,-0.17760269665740328,-0.38863123561707724,-1.4717971480910825,-0.17760269665740328,-1.0103589569207994,-0.268261621890122,0.46563549531765897,0.24960427184179984,0.28036976760383425,0.24960427184179984,0.004668675743301722,-0.35859411376495665,-0.2380779229637603,0.7456315061409986,0.7456315061409986,-0.056227562452395775,0.4966235150833113,0.7456315061409986,-0.9519302317950293,0.4346787153903801,0.34199761865011447,0.34199761865011447,-0.35859411376495665,0.157503833136453,0.18817110729581882,0.12686969850312335,1.0911081847929223,0.46563549531765897,0.8081839940334757,0.40375335457087713,0.8708541043895993,0.7143997644606782,0.8395044242627464,-0.7165186604646431,0.157503833136453,12.67744443719016,0.24960427184179984,0.4346787153903801,0.5897732536440574,-0.298409052876078,0.24960427184179984,-0.5382522425398498,0.157503833136453,0.40375335457087713,-0.08662385171865596,0.7456315061409986,-0.025796646179977383,1.0280359415852773,-0.17760269665740328,-0.8933290661726461,-0.5680616178685269,0.4966235150833113,0.46563549531765897,0.5276425976297412,-0.32851996753944923,0.7143997644606782,0.8708541043895993,0.4346787153903801,0.24960427184179984,0.683197904709607,0.9650771179059916,0.09626890734001688,0.40375335457087713,-0.1169852894996316,0.558692568069395,0.09626890734001688,-1.0976762202817745,0.28036976760383425,0.157503833136453,0.18817110729581882,0.09626890734001688,1.5037658050599132,0.7143997644606782,1.154292705937211,0.40375335457087713,-0.025796646179977383,0.6208844836851677,1.0911081847929223,-0.025796646179977383,0.18817110729581882,0.34199761865011447,0.46563549531765897,0.4346787153903801,0.37285959438321625,0.46563549531765897,1.3763068074774625,0.8395044242627464,0.18817110729581882,0.9650771179059916,0.28036976760383425,0.12686969850312335,0.4966235150833113,-0.025796646179977383,0.37285959438321625,0.7456315061409986,-0.2380779229637603,0.6208844836851677,1.12268648099708,0.558692568069395,0.06570166634344686,0.004668675743301722,0.9965422799663923,0.40375335457087713,1.12268648099708,0.8708541043895993,0.035168185019498165,0.5276425976297412,0.09626890734001688,0.4966235150833113,0.6208844836851677,0.18817110729581882,0.8395044242627464,1.12268648099708,-0.6275632860710119,0.6208844836851677,0.34199761865011447,0.035168185019498165,-0.5084042217553665,0.40375335457087713,-0.056227562452395775,-1.0976762202817745,-0.38863123561707724,0.4346787153903801,0.34199761865011447,0.683197904709607,-0.41863107325011994,0.37285959438321625,0.28036976760383425,0.4346787153903801,1.154292705937211,0.8081839940334757,0.28036976760383425,-0.17760269665740328,0.37285959438321625,-0.14731164812392894,-0.2078582008305619,0.7768929689687475,-0.6572549942161213,0.31116761353809186,0.558692568069395,-0.7756206036620558,0.40375335457087713,1.0911081847929223
2,808
Alternative mrna splicing via spliceosome
19
41
2.225463
0.02605
P14866,P09651,Q13242,O75525,Q92841,Q9UNW9,Q00839,Q15287,P49756,P17844,Q07666,Q07955,Q9BWF3,Q08211,P38159,P51114,P52272,P62995,Q9Y2W1
Processes and pathways
GO Biological process
msigdb_gobp
249,499,139,381,691,701,289,681,287,665,554,555,103,470,106,237,359,122,535
1548,809,381,499,249,665,982,1488,1491,106,287,237,1996,359,1033,122,674,289,1649,554,555,470,1039,139,1361,1771,1432,681,1236,2597,691,1909,893,1445,2389,103,2020,701,535,2022,1070
-0.056227562452395775,0.31116761353809186,0.6520260895751347,0.5276425976297412,0.8395044242627464,0.40375335457087713,0.21887131973311785,-0.025796646179977383,-0.025796646179977383,1.3445088870289958,0.7768929689687475,0.8708541043895993,-0.268261621890122,0.683197904709607,0.18817110729581882,1.2492775721878775,0.40375335457087713,0.7768929689687475,-0.08662385171865596,0.4966235150833113,0.4966235150833113,0.558692568069395,0.18817110729581882,1.154292705937211,0.035168185019498165,-0.14731164812392894,0.004668675743301722,0.40375335457087713,0.09626890734001688,-1.0395078899761159,0.40375335457087713,-0.2078582008305619,0.28036976760383425,0.004668675743301722,-0.6275632860710119,1.3763068074774625,-0.268261621890122,0.40375335457087713,0.5276425976297412,-0.268261621890122,0.18817110729581882
2,808
Tetratricopeptide-like helical domain superfamily [IPR011990]
18
78
2.224293
0.026129
Q92552,Q9H7B4,Q96EY7,Q5R3I4,Q6DKK2,Q9UJX4,Q9BZJ0,O75153,Q6P3X3,O43765,Q9Y5Q9,O75718,Q92791,Q13217,Q32P28,Q8IWR0,Q9BQ70,Q96BR5
Sequence
InterPro Superfamily
interpro_homologous_superfamily
293,5,345,39,163,144,347,179,140,265,322,22,59,152,222,61,126,226
2698,1874,1875,1547,2513,1466,265,402,179,22,2506,707,1395,811,1336,385,984,1344,822,1029,1417,714,2746,1763,1422,1506,2151,2152,1101,337,1230,2115,152,2153,2117,2184,598,2329,2002,1433,637,520,222,39,163,140,2186,2009,1238,1848,1904,61,293,59,226,2638,1380,345,790,1532,126,1313,347,1862,1009,5,1255,2392,1543,1793,144,2136,905,2503,1870,702,322,490
-1.5856145428378061,-0.2078582008305619,-0.2078582008305619,-0.056227562452395775,-0.8639647040355153,-0.025796646179977383,0.8081839940334757,0.6208844836851677,1.0280359415852773,2.8661831768006865,-0.8345582822732515,0.37285959438321625,0.004668675743301722,0.31116761353809186,0.035168185019498165,0.6520260895751347,0.21887131973311785,0.035168185019498165,0.31116761353809186,0.18817110729581882,0.004668675743301722,0.37285959438321625,-2.091044935714574,-0.14731164812392894,0.004668675743301722,-0.025796646179977383,-0.38863123561707724,-0.38863123561707724,0.157503833136453,0.7143997644606782,0.09626890734001688,-0.35859411376495665,1.12268648099708,-0.38863123561707724,-0.35859411376495665,-0.41863107325011994,0.46563549531765897,-0.5680616178685269,-0.268261621890122,0.004668675743301722,0.4346787153903801,0.5276425976297412,0.9336406021056348,2.3421983106958013,1.0911081847929223,1.154292705937211,-0.41863107325011994,-0.268261621890122,0.09626890734001688,-0.17760269665740328,-0.2078582008305619,1.8564295019872012,0.7768929689687475,1.8886425503706181,0.9336406021056348,-1.1846120516744418,0.035168185019498165,0.7143997644606782,0.34199761865011447,-0.025796646179977383,1.2492775721878775,0.06570166634344686,0.7143997644606782,-0.17760269665740328,0.21887131973311785,5.772234941394142,0.09626890734001688,-0.6275632860710119,-0.025796646179977383,-0.14731164812392894,1.154292705937211,-0.35859411376495665,0.28036976760383425,-0.8051101382923185,-0.17760269665740328,0.40375335457087713,0.7456315061409986,0.558692568069395
2,808
Deafness
10
47
2.221547
0.026314
P33527,O95831,Q06124,O60443,Q16740,P19447,P83876,P21281,O75616,Q13217
Drugs and Diseases
Protein Atlas Disease involvement
protein_atlas_disease_involvement
307,8,15,16,46,267,336,357,354,152
2317,16,2100,1555,354,1689,2506,8,1886,406,267,357,1340,1938,1027,307,2400,2370,1149,669,1287,2296,1153,935,1582,336,15,471,152,773,2465,1958,1105,1106,46,2087,2088,952,1309,1605,1385,2409,900,1324,2201,2642,853
-0.5680616178685269,3.5958362789375626,-0.35859411376495665,-0.056227562452395775,0.683197904709607,-0.1169852894996316,-0.8345582822732515,5.599558398962463,-0.2078582008305619,0.6208844836851677,0.8081839940334757,0.683197904709607,0.035168185019498165,-0.2380779229637603,0.18817110729581882,0.7456315061409986,-0.6572549942161213,-0.6275632860710119,0.12686969850312335,0.40375335457087713,0.06570166634344686,-0.5382522425398498,0.12686969850312335,0.24960427184179984,-0.056227562452395775,0.7143997644606782,3.6292428778432244,0.558692568069395,1.12268648099708,0.34199761865011447,-0.7460900042688136,-0.2380779229637603,0.157503833136453,0.157503833136453,2.1796705270663246,-0.32851996753944923,-0.32851996753944923,0.24960427184179984,0.06570166634344686,-0.056227562452395775,0.035168185019498165,-0.6572549942161213,0.28036976760383425,0.06570166634344686,-0.41863107325011994,-1.2135080634726585,0.31116761353809186
2,808
Regulation of alternative mrna splicing via spliceosome
15
31
2.198225
0.027933
P14866,Q9UNW9,Q00839,Q15287,P49756,Q9BWF3,P38159,P09651,O75525,P17844,P51114,Q92841,P62995,Q9Y2W1,Q07666
Processes and pathways
GO Biological process
msigdb_gobp
249,701,289,681,287,103,106,499,381,665,237,691,122,535,554
1548,381,499,249,665,1488,1491,106,287,237,1996,1033,122,674,289,1649,554,1361,1432,681,1236,2597,691,1909,1445,2389,103,2020,701,535,1070
-0.056227562452395775,0.6520260895751347,0.5276425976297412,0.8395044242627464,0.40375335457087713,-0.025796646179977383,-0.025796646179977383,1.3445088870289958,0.7768929689687475,0.8708541043895993,-0.268261621890122,0.18817110729581882,1.2492775721878775,0.40375335457087713,0.7768929689687475,-0.08662385171865596,0.4966235150833113,0.035168185019498165,0.004668675743301722,0.40375335457087713,0.09626890734001688,-1.0395078899761159,0.40375335457087713,-0.2078582008305619,0.004668675743301722,-0.6275632860710119,1.3763068074774625,-0.268261621890122,0.40375335457087713,0.5276425976297412,0.18817110729581882
2,808
Aortic aneurysm
11
51
2.192725
0.028327
Q5TBB1,Q9BYW2,P55011,Q9UBS4,Q96PZ0,P42858,P01889,Q9UJX6,Q96PU5,P61978,P55265
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
391,529,361,400,53,24,23,430,25,150,334
1546,1686,1689,1801,2063,2284,2065,23,544,1935,1340,1811,867,2291,924,24,1350,1641,824,1351,361,334,150,1645,1093,1584,1161,1649,1295,1772,833,2377,391,2083,1238,2469,1240,1054,1003,25,53,1004,529,800,400,1921,738,430,1457,909,536
-0.056227562452395775,-0.1169852894996316,-0.1169852894996316,-0.17760269665740328,-0.32851996753944923,-0.5382522425398498,-0.32851996753944923,2.8661831768006865,0.4966235150833113,-0.2380779229637603,0.035168185019498165,-0.17760269665740328,0.28036976760383425,-0.5382522425398498,0.24960427184179984,2.8661831768006865,0.035168185019498165,-0.08662385171865596,0.31116761353809186,0.035168185019498165,0.683197904709607,0.7143997644606782,1.12268648099708,-0.08662385171865596,0.157503833136453,-0.056227562452395775,0.12686969850312335,-0.08662385171865596,0.06570166634344686,-0.14731164812392894,0.31116761353809186,-0.6275632860710119,0.6520260895751347,-0.32851996753944923,0.09626890734001688,-0.7460900042688136,0.09626890734001688,0.18817110729581882,0.21887131973311785,2.833264740413757,2.017743302585445,0.21887131973311785,0.5276425976297412,0.34199761865011447,0.6520260895751347,-0.2078582008305619,0.37285959438321625,0.6208844836851677,0.004668675743301722,0.28036976760383425,0.5276425976297412
2,808
Neoplasm of the nervous system
14
42
2.190647
0.028477
Q99496,P11388,O75874,Q9BYW2,Q15555,Q06124,O96017,Q15437,Q969G3,P48735,P51532,Q12824,P02545,Q9UJX6
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
573,501,100,529,273,15,110,111,50,19,509,207,544,430
859,100,110,544,1213,1631,545,1339,501,1937,818,921,1408,1490,871,2441,1897,2073,19,509,1290,2180,1584,2261,2420,941,15,1037,2495,207,1105,111,273,683,2380,1052,50,1004,573,529,1733,430
0.28036976760383425,1.3763068074774625,1.312737953942776,0.4966235150833113,0.09626890734001688,-0.08662385171865596,0.4966235150833113,0.035168185019498165,0.5276425976297412,-0.2380779229637603,0.31116761353809186,0.24960427184179984,0.004668675743301722,-0.025796646179977383,0.28036976760383425,-0.7165186604646431,-0.2078582008305619,-0.32851996753944923,2.9650707110154166,0.5276425976297412,0.06570166634344686,-0.41863107325011994,-0.056227562452395775,-0.5084042217553665,-0.686906887210775,0.24960427184179984,3.6292428778432244,0.18817110729581882,-0.8051101382923185,0.9650771179059916,0.157503833136453,1.312737953942776,0.8081839940334757,0.40375335457087713,-0.6275632860710119,0.18817110729581882,2.0824413152506027,0.21887131973311785,0.4966235150833113,0.5276425976297412,-0.1169852894996316,0.6208844836851677
2,808
Negative regulation of mrna processing
11
22
2.187308
0.02872
Q16629,Q07021,Q15287,P18615,P38159,P26368,Q13242,P22626,P98175,Q5VTR2,P61978
Processes and pathways
GO Biological process
msigdb_gobp
253,312,681,464,106,284,139,137,674,95,150
1206,1548,1557,1076,464,137,284,1488,106,150,674,312,1294,1039,139,1361,681,253,95,2186,2233,728
0.09626890734001688,-0.056227562452395775,-0.056227562452395775,0.157503833136453,0.558692568069395,1.154292705937211,0.7768929689687475,-0.025796646179977383,1.3445088870289958,1.12268648099708,0.40375335457087713,0.7456315061409986,0.06570166634344686,0.18817110729581882,1.154292705937211,0.035168185019498165,0.40375335457087713,0.8395044242627464,1.4399830962547482,-0.41863107325011994,-0.47851783636555056,0.37285959438321625
2,808
Transport of the slbp dependant mature mrna
11
30
2.184961
0.028892
Q9BW27,Q8NFH4,P57740,Q96EE3,O15504,Q09161,Q9UBU9,Q86V81,P37198,Q12769,Q9BTX1
Processes and pathways
Reactome Pathways
msigdb_reactome
199,606,593,232,656,365,320,340,331,597,296
656,1334,1142,1413,331,1223,714,1821,1947,593,1583,365,597,1182,951,340,1525,1526,606,1186,1001,1374,232,1248,296,1535,199,1735,320,1868
0.40375335457087713,0.035168185019498165,0.12686969850312335,0.004668675743301722,0.7143997644606782,0.09626890734001688,0.37285959438321625,-0.17760269665740328,-0.2380779229637603,0.46563549531765897,-0.056227562452395775,0.683197904709607,0.46563549531765897,0.12686969850312335,0.24960427184179984,0.7143997644606782,-0.025796646179977383,-0.025796646179977383,0.46563549531765897,0.12686969850312335,0.21887131973311785,0.035168185019498165,0.9022328809207614,0.09626890734001688,0.7768929689687475,-0.025796646179977383,0.9965422799663923,-0.1169852894996316,0.7456315061409986,-0.17760269665740328
2,808
Rrna modification in the nucleus and cytosol
28
55
2.181024
0.029182
Q15061,O75691,Q14692,Q9NQZ2,Q8IWA0,Q9NV31,Q9UJK0,Q9BVJ6,Q9Y6V7,Q9Y5J1,O00567,Q9NX24,O15213,O60832,Q13601,P55769,P46087,Q9NV06,Q8IY37,Q969X6,Q8TED0,Q9NRX1,Q14690,Q9H0A0,P78316,Q9UNX4,Q9Y2R4,Q8NI36
Processes and pathways
Reactome Pathways
msigdb_reactome
251,497,272,159,564,699,700,420,172,703,655,577,538,539,313,672,308,203,605,479,211,227,598,104,595,651,654,642
1549,972,655,538,1879,539,497,1698,1024,308,1761,672,1953,2076,1226,595,1587,313,598,272,251,2447,2305,564,605,642,211,1726,479,2621,1534,420,104,1064,898,1193,1539,159,227,203,699,577,2135,1065,2392,2277,700,2168,651,906,654,907,742,703,172
-0.056227562452395775,0.21887131973311785,0.40375335457087713,0.4966235150833113,-0.2078582008305619,0.4966235150833113,0.5276425976297412,-0.1169852894996316,0.18817110729581882,0.7456315061409986,-0.14731164812392894,0.40375335457087713,-0.2380779229637603,-0.32851996753944923,0.09626890734001688,0.46563549531765897,-0.056227562452395775,0.7456315061409986,0.46563549531765897,0.8081839940334757,0.8395044242627464,-0.7165186604646431,-0.5382522425398498,0.4966235150833113,0.46563549531765897,0.4346787153903801,0.9650771179059916,-0.1169852894996316,0.558692568069395,-1.0976762202817745,-0.025796646179977383,0.6208844836851677,1.3763068074774625,0.18817110729581882,0.28036976760383425,0.12686969850312335,-0.025796646179977383,1.12268648099708,0.9336406021056348,0.9965422799663923,0.40375335457087713,0.4966235150833113,-0.35859411376495665,0.18817110729581882,-0.6275632860710119,-0.5084042217553665,0.40375335457087713,-0.38863123561707724,0.4346787153903801,0.28036976760383425,0.4346787153903801,0.28036976760383425,0.37285959438321625,0.40375335457087713,1.0911081847929223
2,808
Increased serum pyruvate
6
28
2.180047
0.029254
Q70HW3,Q5JRX3,O95831,Q9Y6M9,O43676,Q8N183
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
3,37,8,178,206,118
206,2061,495,2415,861,8,1883,1884,2681,2346,2615,2289,921,1217,821,669,826,1105,37,3,118,276,1605,2749,2314,2201,1738,178
0.9650771179059916,-0.32851996753944923,0.5276425976297412,-0.686906887210775,0.28036976760383425,5.599558398962463,-0.2078582008305619,-0.2078582008305619,-1.443251300169841,-0.5978320623763692,-1.0976762202817745,-0.5382522425398498,0.24960427184179984,0.09626890734001688,0.31116761353809186,0.40375335457087713,0.31116761353809186,0.157503833136453,2.3747748432232223,7.59192311238963,1.2809941384574963,0.8081839940334757,-0.056227562452395775,-2.118822245842012,-0.5382522425398498,-0.41863107325011994,-0.1169852894996316,1.0595579576867387
2,808
Hyperostosis
7
13
2.171577
0.029888
P18074,Q02750,P09651,P22626,Q92889,P19447,P51812
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
406,109,499,137,119,267,148
499,1339,406,267,1340,137,148,1764,109,689,119,1054,1926
0.5276425976297412,0.035168185019498165,0.6208844836851677,0.8081839940334757,0.035168185019498165,1.154292705937211,1.12268648099708,-0.14731164812392894,1.3445088870289958,0.40375335457087713,1.2809941384574963,0.18817110729581882,-0.2078582008305619
2,808
Aplasia hypoplasia of the skin
14
50
2.171259
0.029912
O96028,P18074,Q13363,Q13126,Q14692,Q15392,Q9NX24,O60832,P19447,Q92889,P21281,P02545,Q96PU5,Q9Y619
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
282,406,135,7,272,11,577,539,267,119,357,544,25,323
1874,2343,539,2062,2063,2569,916,282,544,1213,662,1339,2248,2418,1144,406,267,357,1340,1408,1812,763,1347,1641,1291,2148,1351,1645,1161,2374,1649,2495,7,135,634,272,1655,2229,11,1238,2560,119,1054,25,1004,2194,614,577,1926,323
-0.2078582008305619,-0.5978320623763692,0.4966235150833113,-0.32851996753944923,-0.32851996753944923,-0.981166329813051,0.24960427184179984,0.7768929689687475,0.4966235150833113,0.09626890734001688,0.40375335457087713,0.035168185019498165,-0.5084042217553665,-0.686906887210775,0.12686969850312335,0.6208844836851677,0.8081839940334757,0.683197904709607,0.035168185019498165,0.004668675743301722,-0.17760269665740328,0.34199761865011447,0.035168185019498165,-0.08662385171865596,0.06570166634344686,-0.38863123561707724,0.035168185019498165,-0.08662385171865596,0.12686969850312335,-0.6275632860710119,-0.08662385171865596,-0.8051101382923185,5.668578356402774,1.185926720770312,0.4346787153903801,0.8081839940334757,-0.08662385171865596,-0.47851783636555056,4.3692130993892455,0.09626890734001688,-0.9519302317950293,1.2809941384574963,0.18817110729581882,2.833264740413757,0.21887131973311785,-0.41863107325011994,0.46563549531765897,0.4966235150833113,-0.2078582008305619,0.7456315061409986
2,808
Nucleosomal dna binding
12
22
2.171233
0.029914
P07305,Q13547,O75367,O95983,P16403,Q969G3,P51532,P52926,O94776,Q12824,P07910,Q8WXI9
Functions
GO Molecular function
msigdb_gomf
587,516,403,75,503,50,509,52,541,207,356,225
403,541,75,2065,2398,587,356,2146,709,503,1481,509,52,207,516,636,1372,225,1967,1308,1857,50
0.6208844836851677,0.4966235150833113,1.663681686992128,-0.32851996753944923,-0.6572549942161213,0.46563549531765897,0.683197904709607,-0.38863123561707724,0.37285959438321625,0.5276425976297412,-0.025796646179977383,0.5276425976297412,2.017743302585445,0.9650771179059916,0.5276425976297412,0.4346787153903801,0.035168185019498165,0.9336406021056348,-0.2380779229637603,0.06570166634344686,-0.17760269665740328,2.0824413152506027
2,808
Abnormality of salivation
12
41
2.170897
0.029939
Q93008,Q15165,Q92804,Q13501,P55795,P43243,P50995,P01889,P55011,Q03252,P35637,P51812
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
373,2,38,136,195,286,358,23,361,363,182,148
2343,2100,1979,23,2417,499,1080,2735,2324,870,182,928,286,764,358,826,1419,148,361,1764,195,1584,363,410,1163,136,1513,1957,2,1515,2662,2270,38,373,1004,2160,2358,2550,1455,2096,2199
-0.5978320623763692,-0.35859411376495665,-0.268261621890122,2.8661831768006865,-0.686906887210775,0.5276425976297412,0.157503833136453,-1.9516992342127442,-0.5680616178685269,0.28036976760383425,1.0280359415852773,0.24960427184179984,0.7768929689687475,0.34199761865011447,0.683197904709607,0.31116761353809186,0.004668675743301722,1.12268648099708,0.683197904709607,-0.14731164812392894,0.9965422799663923,-0.056227562452395775,0.683197904709607,0.6208844836851677,0.12686969850312335,1.185926720770312,-0.025796646179977383,-0.2380779229637603,8.624354780633901,-0.025796646179977383,-1.3286908083244282,-0.5084042217553665,2.3747748432232223,0.683197904709607,0.21887131973311785,-0.38863123561707724,-0.5978320623763692,-0.922651025281217,0.004668675743301722,-0.32851996753944923,-0.41863107325011994
2,808
Rrna metabolic process
88
171
2.169281
0.030061
O75691,P51532,Q8IWA0,Q9H7B2,Q9NX24,O15213,O60832,O60287,Q13206,Q8IY37,Q9BYG3,Q9GZR2,Q9P0M6,Q14690,Q99848,Q9H0A0,P78316,Q5JTH9,Q9BZE4,Q9UKN8,Q9UNX4,Q9Y2R4,Q8NI36,P42285,Q9BSC4,Q9NY93,Q76FK4,Q9NQZ2,Q92841,Q9BV38,Q9NV31,Q9UJK0,Q14978,Q9Y6V7,Q9Y5J1,Q9BXY0,O00567,Q14684,P55769,Q9H9Y2,Q9NV06,Q9GZL7,Q9Y2L1,Q9H501,Q9Y3A2,Q8TED0,Q12824,P19338,P39019,O95478,Q15024,Q9NVP1,Q8NEF9,Q9H9J2,Q9BYD6,Q9H0D6,Q15061,Q9UQ80,Q9P2D1,Q9Y2W2,Q14692,O43290,O15381,Q9Y3B9,P56182,Q9Y5Q9,Q9NQ55,Q13601,Q06265,P46087,Q8N9T8,Q15050,P42766,P62841,Q8TDN6,Q8WUA4,O76021,Q9NQT5,Q9NX58,Q9P275,Q9BVJ6,P18074,O75367,Q5RKV6,Q969X6,Q9Y4W2,Q9NR30,Q8IY81
Processes and pathways
GO Biological process
msigdb_gobp
497,509,564,574,577,538,539,51,557,605,611,613,617,598,88,104,595,639,647,649,651,654,642,627,143,161,686,159,691,696,699,700,680,172,703,170,655,162,672,735,203,731,741,213,742,211,207,710,711,708,241,244,242,243,795,257,251,801,800,280,272,264,263,301,288,322,319,313,311,308,343,339,332,335,370,394,382,424,425,428,420,406,403,445,479,489,486,525
1549,806,972,655,1465,538,263,2060,264,1879,51,539,403,497,2505,382,708,1213,1019,406,978,1404,710,1024,1028,711,627,822,332,308,2292,2533,509,672,288,1421,2111,990,1158,1953,1503,2209,2076,1706,1423,1226,335,1832,2149,2684,1833,2586,595,938,875,939,2114,311,1587,2263,207,557,944,313,2558,773,2118,1103,1169,162,598,272,680,241,339,251,2447,1111,639,445,2043,2305,1114,686,1851,2534,2333,564,605,525,2384,2089,343,242,642,953,370,211,394,1242,691,1726,479,1244,2621,1121,1056,88,143,696,1534,420,170,795,611,647,731,613,1785,104,257,1064,213,898,1193,574,1539,243,735,1450,319,1970,424,159,486,1317,203,699,244,577,425,1065,161,2392,617,428,800,2277,700,1617,649,2622,2168,651,801,2200,741,906,654,280,907,742,1794,1928,301,489,2490,703,1873,322,172
-0.056227562452395775,0.31116761353809186,0.21887131973311785,0.40375335457087713,-0.025796646179977383,0.4966235150833113,0.8081839940334757,-0.32851996753944923,0.8081839940334757,-0.2078582008305619,2.017743302585445,0.4966235150833113,0.6208844836851677,0.5276425976297412,-0.8345582822732515,0.6520260895751347,0.37285959438321625,0.09626890734001688,0.18817110729581882,0.6208844836851677,0.21887131973311785,0.004668675743301722,0.37285959438321625,0.18817110729581882,0.18817110729581882,0.37285959438321625,0.4346787153903801,0.31116761353809186,0.7143997644606782,0.7456315061409986,-0.5382522425398498,-0.8933290661726461,0.5276425976297412,0.40375335457087713,0.7768929689687475,0.004668675743301722,-0.35859411376495665,0.21887131973311785,0.12686969850312335,-0.2380779229637603,-0.025796646179977383,-0.448593362815423,-0.32851996753944923,-0.1169852894996316,0.004668675743301722,0.09626890734001688,0.7143997644606782,-0.17760269665740328,-0.38863123561707724,-1.4717971480910825,-0.17760269665740328,-1.0103589569207994,0.46563549531765897,0.24960427184179984,0.28036976760383425,0.24960427184179984,-0.35859411376495665,0.7456315061409986,-0.056227562452395775,-0.5084042217553665,0.9650771179059916,0.4966235150833113,0.24960427184179984,0.7456315061409986,-0.9519302317950293,0.34199761865011447,-0.35859411376495665,0.157503833136453,0.12686969850312335,1.0911081847929223,0.46563549531765897,0.8081839940334757,0.40375335457087713,0.8708541043895993,0.7143997644606782,0.8395044242627464,-0.7165186604646431,0.157503833136453,0.4346787153903801,0.5897732536440574,-0.298409052876078,-0.5382522425398498,0.157503833136453,0.40375335457087713,-0.17760269665740328,-0.8933290661726461,-0.5680616178685269,0.4966235150833113,0.46563549531765897,0.5276425976297412,-0.6275632860710119,-0.32851996753944923,0.7143997644606782,0.8708541043895993,0.4346787153903801,0.24960427184179984,0.683197904709607,0.9650771179059916,0.6520260895751347,0.09626890734001688,0.40375335457087713,-0.1169852894996316,0.558692568069395,0.09626890734001688,-1.0976762202817745,0.157503833136453,0.18817110729581882,1.5037658050599132,1.154292705937211,0.40375335457087713,-0.025796646179977383,0.6208844836851677,1.0911081847929223,0.34199761865011447,0.46563549531765897,0.4346787153903801,0.37285959438321625,0.46563549531765897,-0.14731164812392894,1.3763068074774625,0.8395044242627464,0.18817110729581882,0.9650771179059916,0.28036976760383425,0.12686969850312335,0.4966235150833113,-0.025796646179977383,0.8708541043895993,0.37285959438321625,0.004668675743301722,0.7456315061409986,-0.2380779229637603,0.6208844836851677,1.12268648099708,0.558692568069395,0.06570166634344686,0.9965422799663923,0.40375335457087713,0.8708541043895993,0.4966235150833113,0.6208844836851677,0.18817110729581882,1.12268648099708,-0.6275632860710119,0.46563549531765897,0.6208844836851677,0.34199761865011447,-0.5084042217553665,0.40375335457087713,-0.056227562452395775,0.4346787153903801,-1.0976762202817745,-0.38863123561707724,0.4346787153903801,0.34199761865011447,-0.41863107325011994,0.37285959438321625,0.28036976760383425,0.4346787153903801,0.8081839940334757,0.28036976760383425,0.37285959438321625,-0.14731164812392894,-0.2078582008305619,0.7768929689687475,0.558692568069395,-0.7756206036620558,0.40375335457087713,-0.17760269665740328,0.7456315061409986,1.0911081847929223
2,808
Regulation of muscle cell differentiation
10
17
2.167992
0.030159
Q13547,Q9BWF3,Q53EL6,P67809,Q15014,P42345,Q9BYT8,Q96EB6,O75179,P04179
Processes and pathways
GO Biological process
msigdb_gobp
516,103,835,362,517,822,484,789,56,462
56,1395,462,1633,1027,1488,822,826,362,516,517,1176,835,1720,789,103,484
1.953143430854237,0.004668675743301722,0.558692568069395,-0.08662385171865596,0.18817110729581882,-0.025796646179977383,0.31116761353809186,0.31116761353809186,0.683197904709607,0.5276425976297412,0.5276425976297412,0.12686969850312335,0.31116761353809186,-0.1169852894996316,0.34199761865011447,1.3763068074774625,0.558692568069395
2,808
Abnormality of the pituitary gland
19
59
2.16749
0.030197
Q8WWQ0,Q14746,Q8NI27,P48735,Q03164,Q9Y285,Q99496,Q15813,Q9BUK6,Q9NW13,Q969G3,Q7Z2Z2,Q8IY37,Q9BZH6,Q12824,Q96IJ6,O75874,P57740,Q9UBS4
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
395,635,689,19,151,30,573,559,49,455,50,314,605,612,207,99,100,593,400
1874,1330,2343,1686,100,2506,1213,1985,1339,2460,1345,871,1347,928,2073,19,1153,932,1290,593,2180,2258,1094,151,1649,1037,207,832,833,635,1958,1515,559,683,1299,314,1850,605,1665,689,395,50,99,1003,1191,573,49,612,1384,1735,2409,2165,455,800,400,2020,1618,30,1794
-0.2078582008305619,0.035168185019498165,-0.5978320623763692,-0.1169852894996316,1.3763068074774625,-0.8345582822732515,0.09626890734001688,-0.268261621890122,0.035168185019498165,-0.7460900042688136,0.035168185019498165,0.28036976760383425,0.035168185019498165,0.24960427184179984,-0.32851996753944923,2.9650707110154166,0.12686969850312335,0.24960427184179984,0.06570166634344686,0.46563549531765897,-0.41863107325011994,-0.5084042217553665,0.157503833136453,1.12268648099708,-0.08662385171865596,0.18817110729581882,0.9650771179059916,0.31116761353809186,0.31116761353809186,0.4346787153903801,-0.2380779229637603,-0.025796646179977383,0.4966235150833113,0.40375335457087713,0.06570166634344686,0.7456315061409986,-0.17760269665740328,0.46563549531765897,-0.08662385171865596,0.40375335457087713,0.6520260895751347,2.0824413152506027,1.4081315864034736,0.21887131973311785,0.12686969850312335,0.4966235150833113,2.1472366342770832,0.46563549531765897,0.035168185019498165,-0.1169852894996316,-0.6572549942161213,-0.38863123561707724,0.5897732536440574,0.34199761865011447,0.6520260895751347,-0.268261621890122,-0.056227562452395775,2.5707228467689385,-0.14731164812392894
2,808
Runx1 interacts with co factors whose precise effect on runx1 targets is not known
6
15
2.164983
0.030389
P19784,Q13951,Q96GM5,Q969G3,P51532,Q12824
Processes and pathways
Reactome Pathways
msigdb_reactome
250,196,166,50,509,207
1267,2065,250,509,1581,207,196,1368,1597,1372,1857,50,166,573,2195
0.06570166634344686,-0.32851996753944923,0.8395044242627464,0.5276425976297412,-0.056227562452395775,0.9650771179059916,0.9965422799663923,0.035168185019498165,-0.056227562452395775,0.035168185019498165,-0.17760269665740328,2.0824413152506027,1.0911081847929223,0.4966235150833113,-0.41863107325011994
2,808
Abnormal femoral neck morphology
7
31
2.155366
0.031133
Q99575,O95831,Q96HY6,Q96AY3,Q9Y619,O75718,P51812
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
233,8,167,47,323,22,148
1463,1686,2062,22,2063,8,544,917,2770,1340,2250,867,1350,1701,148,361,2258,1431,636,1376,47,167,1054,233,2094,1786,2051,1737,1794,1070,323
-0.025796646179977383,-0.1169852894996316,-0.32851996753944923,2.8661831768006865,-0.32851996753944923,5.599558398962463,0.4966235150833113,0.24960427184179984,-2.6683718860934924,0.035168185019498165,-0.5084042217553665,0.28036976760383425,0.035168185019498165,-0.1169852894996316,1.12268648099708,0.683197904709607,-0.5084042217553665,0.004668675743301722,0.4346787153903801,0.035168185019498165,2.1796705270663246,1.0911081847929223,0.18817110729581882,0.9022328809207614,-0.32851996753944923,-0.14731164812392894,-0.298409052876078,-0.1169852894996316,-0.14731164812392894,0.18817110729581882,0.7456315061409986
2,808
Chromatin modifying enzymes
22
62
2.1484
0.031682
Q13547,Q9H7B4,O95163,P51532,Q6IA86,Q03164,O96028,Q96GM5,P11802,Q969G3,O94776,P29375,Q86X55,O95983,Q12824,Q8WXI9,Q8NB78,Q86YP4,Q15014,Q15022,P61964,Q9BYW2
Processes and pathways
Reactome Pathways
msigdb_reactome
516,5,498,509,561,151,282,166,283,50,541,181,341,75,207,225,368,524,517,518,238,529
1548,1267,1072,2316,2513,809,1394,541,498,2458,542,75,2065,282,283,1698,1808,181,509,1419,238,629,1507,151,207,1166,516,636,517,518,834,2264,1234,561,2467,1849,1368,341,524,368,1372,225,1308,1857,50,1673,166,693,961,2579,529,5,1609,2431,1867,1263,2362,1923,1204,2581,853,2527
-0.056227562452395775,0.06570166634344686,0.157503833136453,-0.5680616178685269,-0.8639647040355153,0.31116761353809186,0.004668675743301722,0.4966235150833113,0.5276425976297412,-0.7460900042688136,0.4966235150833113,1.663681686992128,-0.32851996753944923,0.7768929689687475,0.7768929689687475,-0.1169852894996316,-0.17760269665740328,1.0280359415852773,0.5276425976297412,0.004668675743301722,0.8708541043895993,0.4346787153903801,-0.025796646179977383,1.12268648099708,0.9650771179059916,0.12686969850312335,0.5276425976297412,0.4346787153903801,0.5276425976297412,0.5276425976297412,0.31116761353809186,-0.5084042217553665,0.09626890734001688,0.4966235150833113,-0.7460900042688136,-0.17760269665740328,0.035168185019498165,0.7143997644606782,0.5276425976297412,0.683197904709607,0.035168185019498165,0.9336406021056348,0.06570166634344686,-0.17760269665740328,2.0824413152506027,-0.08662385171865596,1.0911081847929223,0.40375335457087713,0.24960427184179984,-0.981166329813051,0.5276425976297412,5.772234941394142,-0.056227562452395775,-0.686906887210775,-0.17760269665740328,0.09626890734001688,-0.5978320623763692,-0.2078582008305619,0.12686969850312335,-0.981166329813051,0.31116761353809186,-0.8639647040355153
2,808
Pectus excavatum
21
71
2.147042
0.03179
Q9Y2W2,Q15555,Q06124,Q9UJX6,O75718,Q03164,P61978,P51812,Q969N2,Q6DKJ4,P08069,Q9BUK6,Q6KC79,O60216,Q9Y4R8,P24928,Q9NWH9,Q02750,Q15437,Q9BYW2,Q9Y4P3
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
280,273,15,430,22,151,150,148,567,560,546,49,446,74,350,329,376,109,111,529,536
1469,74,1686,2062,22,544,2722,1935,1631,546,1340,818,921,1990,329,1221,924,928,1152,826,1153,148,1351,593,150,1645,1708,1093,674,109,1161,151,15,1649,1038,832,2377,111,273,2378,1303,560,446,1438,2469,1240,1723,1600,2270,567,1376,2578,1781,1054,1006,1446,49,529,2358,1008,1786,1677,376,2020,738,430,1203,1391,280,536,350
-0.025796646179977383,1.663681686992128,-0.1169852894996316,-0.32851996753944923,2.8661831768006865,0.4966235150833113,-1.783438896118417,-0.2380779229637603,-0.08662385171865596,0.4966235150833113,0.035168185019498165,0.31116761353809186,0.24960427184179984,-0.268261621890122,0.7143997644606782,0.09626890734001688,0.24960427184179984,0.24960427184179984,0.12686969850312335,0.31116761353809186,0.12686969850312335,1.12268648099708,0.035168185019498165,0.46563549531765897,1.12268648099708,-0.08662385171865596,-0.1169852894996316,0.157503833136453,0.40375335457087713,1.3445088870289958,0.12686969850312335,1.12268648099708,3.6292428778432244,-0.08662385171865596,0.18817110729581882,0.31116761353809186,-0.6275632860710119,1.312737953942776,0.8081839940334757,-0.6275632860710119,0.06570166634344686,0.4966235150833113,0.5897732536440574,0.004668675743301722,-0.7460900042688136,0.09626890734001688,-0.1169852894996316,-0.056227562452395775,-0.5084042217553665,0.4966235150833113,0.035168185019498165,-0.981166329813051,-0.14731164812392894,0.18817110729581882,0.21887131973311785,0.004668675743301722,2.1472366342770832,0.5276425976297412,-0.5978320623763692,0.21887131973311785,-0.14731164812392894,-0.08662385171865596,0.683197904709607,-0.268261621890122,0.37285959438321625,0.6208844836851677,0.12686969850312335,0.035168185019498165,0.8081839940334757,0.5276425976297412,0.7143997644606782
2,808
Histone deacetylation
14
29
2.144885
0.031962
Q96PK6,Q13547,Q13363,O95983,Q9H4L7,Q86YP4,O43823,Q15014,O94776,P61964,Q8WXI9,Q6KC79,P29375,Q9ULX6
Processes and pathways
GO Biological process
msigdb_gobp
168,516,135,75,614,524,78,517,541,238,225,446,181,62
2060,78,541,75,1213,982,181,2255,238,1507,1166,135,516,636,517,446,524,2307,225,1308,789,168,1191,614,1867,2628,1263,2362,62
-0.32851996753944923,1.631646524525365,0.4966235150833113,1.663681686992128,0.09626890734001688,0.21887131973311785,1.0280359415852773,-0.5084042217553665,0.8708541043895993,-0.025796646179977383,0.12686969850312335,1.185926720770312,0.5276425976297412,0.4346787153903801,0.5276425976297412,0.5897732536440574,0.5276425976297412,-0.5382522425398498,0.9336406021056348,0.06570166634344686,0.34199761865011447,1.0911081847929223,0.12686969850312335,0.46563549531765897,-0.17760269665740328,-1.1266965842029726,0.09626890734001688,-0.5978320623763692,1.8564295019872012
2,808
Prematurely aged appearance
11
34
2.133602
0.032875
P18074,Q13126,Q02750,Q9NX24,Q06124,O60832,P19447,Q15042,Q92889,Q03252,Q9Y4P3
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
406,7,109,577,15,539,267,186,119,363,536
2343,539,2062,2063,916,544,662,2572,406,267,1407,1812,924,1757,926,1758,1944,1351,1093,109,1161,363,15,7,186,2377,2083,119,1120,1008,577,738,2136,536
-0.5978320623763692,0.4966235150833113,-0.32851996753944923,-0.32851996753944923,0.24960427184179984,0.4966235150833113,0.40375335457087713,-0.981166329813051,0.6208844836851677,0.8081839940334757,0.004668675743301722,-0.17760269665740328,0.24960427184179984,-0.14731164812392894,0.24960427184179984,-0.14731164812392894,-0.2380779229637603,0.035168185019498165,0.157503833136453,1.3445088870289958,0.12686969850312335,0.683197904709607,3.6292428778432244,5.668578356402774,1.0280359415852773,-0.6275632860710119,-0.32851996753944923,1.2809941384574963,0.157503833136453,0.21887131973311785,0.4966235150833113,0.37285959438321625,-0.35859411376495665,0.5276425976297412
2,808
Protein polyubiquitination
12
45
2.129043
0.033251
O95376,Q9H000,Q13951,Q9UJX4,Q05086,Q9Y4X5,P55786,Q96FW1,P19474,Q9UJX6,Q96PU5,Q5VTR2
Processes and pathways
GO Biological process
msigdb_gobp
90,235,196,144,410,378,18,190,85,430,25,95
1207,1557,1079,90,85,1639,984,871,510,18,2298,1505,2079,410,2115,2484,1362,1231,1589,196,411,1772,2633,2523,95,2468,1240,190,1781,25,1251,963,235,2194,1542,2488,1543,1793,144,430,851,650,2136,1619,378
0.09626890734001688,-0.056227562452395775,0.157503833136453,1.4399830962547482,1.5356967553836633,-0.08662385171865596,0.21887131973311785,0.28036976760383425,0.5276425976297412,3.163433416765019,-0.5382522425398498,-0.025796646179977383,-0.32851996753944923,0.6208844836851677,-0.35859411376495665,-0.7756206036620558,0.035168185019498165,0.09626890734001688,-0.056227562452395775,0.9965422799663923,0.6208844836851677,-0.14731164812392894,-1.1556750417424753,-0.8639647040355153,1.4399830962547482,-0.7460900042688136,0.09626890734001688,1.0280359415852773,-0.14731164812392894,2.833264740413757,0.09626890734001688,0.24960427184179984,0.9022328809207614,-0.41863107325011994,-0.025796646179977383,-0.7756206036620558,-0.025796646179977383,-0.14731164812392894,1.154292705937211,0.6208844836851677,0.31116761353809186,0.4346787153903801,-0.35859411376495665,-0.056227562452395775,0.683197904709607
2,808
Dwarfism
8
44
2.127808
0.033353
Q99575,O95831,Q96HY6,Q92889,P52926,Q96PZ0,O75718,Q32P28
Drugs and Diseases
Protein Atlas Disease involvement
protein_atlas_disease_involvement
233,8,167,119,52,53,22,222
2762,2396,1463,1268,1686,22,1934,8,1985,1886,406,267,1990,2250,1277,1280,669,763,2371,1701,824,52,935,2404,634,773,1957,1431,559,222,883,560,685,1849,1598,119,167,1054,1003,53,1191,233,2272,2051
-2.2572634211995095,-0.6572549942161213,-0.025796646179977383,0.06570166634344686,-0.1169852894996316,2.8661831768006865,-0.2380779229637603,5.599558398962463,-0.268261621890122,-0.2078582008305619,0.6208844836851677,0.8081839940334757,-0.268261621890122,-0.5084042217553665,0.06570166634344686,0.06570166634344686,0.40375335457087713,0.34199761865011447,-0.6275632860710119,-0.1169852894996316,0.31116761353809186,2.017743302585445,0.24960427184179984,-0.6572549942161213,0.4346787153903801,0.34199761865011447,-0.2380779229637603,0.004668675743301722,0.4966235150833113,0.9336406021056348,0.28036976760383425,0.4966235150833113,0.40375335457087713,-0.17760269665740328,-0.056227562452395775,1.2809941384574963,1.0911081847929223,0.18817110729581882,0.21887131973311785,2.017743302585445,0.12686969850312335,0.9022328809207614,-0.5084042217553665,-0.298409052876078
2,808
Abnormality of alkaline phosphatase level
9
18
2.126883
0.03343
Q96S52,Q8N511,Q969N2,Q9Y5L0,Q13501,P09651,O96017,P22626,Q96AY3
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
397,34,567,704,136,499,110,137,47
110,1213,499,664,137,1764,136,1957,1117,34,2499,567,1376,47,397,1786,1616,704
1.312737953942776,0.09626890734001688,0.5276425976297412,0.40375335457087713,1.154292705937211,-0.14731164812392894,1.185926720770312,-0.2380779229637603,0.157503833136453,2.4073748090514258,-0.8051101382923185,0.4966235150833113,0.035168185019498165,2.1796705270663246,0.6520260895751347,-0.14731164812392894,-0.056227562452395775,0.40375335457087713
2,808
Broad finger
8
30
2.122958
0.033757
Q93008,O14936,P55011,Q15022,Q96PZ0,P42858,Q8WXI9,P51812
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
373,246,361,518,53,24,225,148
1546,246,1686,1689,2065,1340,1811,24,148,361,1038,1295,773,1772,1431,518,560,2469,1240,225,373,2126,1054,53,1384,1921,2020,1737,1457,1070
-0.056227562452395775,0.8395044242627464,-0.1169852894996316,-0.1169852894996316,-0.32851996753944923,0.035168185019498165,-0.17760269665740328,2.8661831768006865,1.12268648099708,0.683197904709607,0.18817110729581882,0.06570166634344686,0.34199761865011447,-0.14731164812392894,0.004668675743301722,0.5276425976297412,0.4966235150833113,-0.7460900042688136,0.09626890734001688,0.9336406021056348,0.683197904709607,-0.35859411376495665,0.18817110729581882,2.017743302585445,0.035168185019498165,-0.2078582008305619,-0.268261621890122,-0.1169852894996316,0.004668675743301722,0.18817110729581882
2,808
Abnormal internal genitalia
31
107
2.122616
0.033786
Q8WWQ0,Q6ZRS2,Q13363,Q06124,P48735,P19447,Q92766,P51812,O96028,P18074,Q9NX24,Q5JTZ9,Q16740,O60832,Q9BW83,P02545,P07954,Q6KC79,Q8IY37,Q9NR50,O60216,Q9BZH6,Q15427,O75874,O96017,Q15437,Q92889,O75616,Q9BYW2,Q03252,Q9Y4P3
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
395,254,135,15,19,267,565,148,282,406,577,413,46,539,54,544,545,446,605,201,74,612,600,100,110,111,119,354,529,363,536
1874,1877,1465,1552,1467,74,1800,539,912,354,2063,100,2569,916,110,282,544,1213,662,545,1339,1141,863,2460,406,267,1937,921,2032,1407,1408,1221,2253,871,924,669,1347,2073,19,1944,2585,764,1577,1153,932,148,1290,1498,593,2180,1358,1093,1094,2261,363,15,1649,1037,2522,135,944,1841,832,1958,2377,1959,600,111,1109,881,683,46,413,1303,446,1237,1438,254,1853,887,2560,605,395,1188,565,956,119,841,1605,54,1447,529,612,896,2194,1450,2627,201,2165,577,800,2220,2167,738,1203,536,1070
-0.2078582008305619,-0.2078582008305619,-0.025796646179977383,-0.056227562452395775,-0.025796646179977383,1.663681686992128,-0.17760269665740328,0.4966235150833113,0.24960427184179984,0.683197904709607,-0.32851996753944923,1.3763068074774625,-0.981166329813051,0.24960427184179984,1.312737953942776,0.7768929689687475,0.4966235150833113,0.09626890734001688,0.40375335457087713,0.4966235150833113,0.035168185019498165,0.12686969850312335,0.28036976760383425,-0.7460900042688136,0.6208844836851677,0.8081839940334757,-0.2380779229637603,0.24960427184179984,-0.298409052876078,0.004668675743301722,0.004668675743301722,0.09626890734001688,-0.5084042217553665,0.28036976760383425,0.24960427184179984,0.40375335457087713,0.035168185019498165,-0.32851996753944923,2.9650707110154166,-0.2380779229637603,-1.0103589569207994,0.34199761865011447,-0.056227562452395775,0.12686969850312335,0.24960427184179984,1.12268648099708,0.06570166634344686,-0.025796646179977383,0.46563549531765897,-0.41863107325011994,0.035168185019498165,0.157503833136453,0.157503833136453,-0.5084042217553665,0.683197904709607,3.6292428778432244,-0.08662385171865596,0.18817110729581882,-0.8639647040355153,1.185926720770312,0.24960427184179984,-0.17760269665740328,0.31116761353809186,-0.2380779229637603,-0.6275632860710119,-0.2380779229637603,0.46563549531765897,1.312737953942776,0.157503833136453,0.28036976760383425,0.40375335457087713,2.1796705270663246,0.6208844836851677,0.06570166634344686,0.5897732536440574,0.09626890734001688,0.004668675743301722,0.8395044242627464,-0.17760269665740328,0.28036976760383425,-0.9519302317950293,0.46563549531765897,0.6520260895751347,0.12686969850312335,0.4966235150833113,0.24960427184179984,1.2809941384574963,0.31116761353809186,-0.056227562452395775,1.985431046332752,0.004668675743301722,0.5276425976297412,0.46563549531765897,0.28036976760383425,-0.41863107325011994,0.004668675743301722,-1.1266965842029726,0.9965422799663923,-0.38863123561707724,0.4966235150833113,0.34199761865011447,-0.448593362815423,-0.38863123561707724,0.37285959438321625,0.12686969850312335,0.5276425976297412,0.18817110729581882
2,808
rRNA processing
38
68
2.122013
0.033837
Q15061,Q9UQ80,Q9P2D1,Q9Y2W2,P42285,O75691,Q9NY93,Q76FK4,Q9NQT5,Q9NX58,Q92841,Q8IWA0,Q9NV31,Q9UJK0,Q9Y5J1,P56182,Q9NX24,O60832,Q13601,Q06265,Q5RKV6,P46087,Q9H9Y2,Q9NV06,Q9GZL7,Q9Y2L1,Q969X6,Q9Y3A2,Q9Y4W2,Q8TED0,Q9NR30,Q14690,O95478,Q9H0A0,P78316,Q15024,Q8IY81,Q8NI36
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
251,801,800,280,627,497,161,686,424,425,691,564,699,700,703,288,577,539,313,311,445,308,735,203,731,741,479,742,489,211,486,598,708,104,595,241,525,642
806,972,2060,1879,539,497,2505,708,1024,1028,627,308,288,1706,595,938,2114,311,313,773,1103,1169,598,241,251,445,2043,686,2333,564,525,2089,642,211,1242,691,1726,479,1244,2621,1056,731,104,1064,898,1539,735,1970,424,486,203,699,577,425,1065,161,2392,800,2277,700,2168,801,741,280,742,1928,489,703
0.31116761353809186,0.21887131973311785,-0.32851996753944923,-0.2078582008305619,0.4966235150833113,0.5276425976297412,-0.8345582822732515,0.37285959438321625,0.18817110729581882,0.18817110729581882,0.4346787153903801,0.7456315061409986,0.7768929689687475,-0.1169852894996316,0.46563549531765897,0.24960427184179984,-0.35859411376495665,0.7456315061409986,0.7456315061409986,0.34199761865011447,0.157503833136453,0.12686969850312335,0.46563549531765897,0.8708541043895993,0.8395044242627464,0.5897732536440574,-0.298409052876078,0.40375335457087713,-0.5680616178685269,0.4966235150833113,0.5276425976297412,-0.32851996753944923,0.4346787153903801,0.9650771179059916,0.09626890734001688,0.40375335457087713,-0.1169852894996316,0.558692568069395,0.09626890734001688,-1.0976762202817745,0.18817110729581882,0.37285959438321625,1.3763068074774625,0.18817110729581882,0.28036976760383425,-0.025796646179977383,0.37285959438321625,-0.2380779229637603,0.6208844836851677,0.558692568069395,0.9965422799663923,0.40375335457087713,0.4966235150833113,0.6208844836851677,0.18817110729581882,1.12268648099708,-0.6275632860710119,0.34199761865011447,-0.5084042217553665,0.40375335457087713,-0.38863123561707724,0.34199761865011447,0.37285959438321625,0.8081839940334757,0.37285959438321625,-0.2078582008305619,0.558692568069395,0.40375335457087713
2,808
Cranial hyperostosis
6
11
2.118798
0.034108
P18074,P09651,P22626,Q92889,P19447,P51812
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
406,499,137,119,267,148
499,1339,406,267,1340,137,148,1764,689,119,1054
0.5276425976297412,0.035168185019498165,0.6208844836851677,0.8081839940334757,0.035168185019498165,1.154292705937211,1.12268648099708,-0.14731164812392894,0.40375335457087713,1.2809941384574963,0.18817110729581882
2,808
Kyphoscoliosis
13
45
2.117432
0.034223
Q8NBU5,Q6ZRS2,Q8TB36,O94992,P18074,Q99575,Q9Y4R8,Q02750,Q06124,Q96AY3,Q9NW13,Q15042,P51812
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
131,254,393,248,406,233,350,109,15,47,455,186,148
2343,1877,1269,861,2063,248,1934,544,1935,2146,406,1081,1340,818,1405,1757,826,148,467,1351,593,2000,109,1161,15,2328,1164,1431,186,1515,1298,885,1438,254,2662,131,393,47,1054,233,1916,2550,455,1737,350
-0.5978320623763692,-0.2078582008305619,0.06570166634344686,0.28036976760383425,-0.32851996753944923,0.8395044242627464,-0.2380779229637603,0.4966235150833113,-0.2380779229637603,-0.38863123561707724,0.6208844836851677,0.157503833136453,0.035168185019498165,0.31116761353809186,0.004668675743301722,-0.14731164812392894,0.31116761353809186,1.12268648099708,0.558692568069395,0.035168185019498165,0.46563549531765897,-0.268261621890122,1.3445088870289958,0.12686969850312335,3.6292428778432244,-0.5680616178685269,0.12686969850312335,0.004668675743301722,1.0280359415852773,-0.025796646179977383,0.06570166634344686,0.28036976760383425,0.004668675743301722,0.8395044242627464,-1.3286908083244282,1.2175883881471963,0.6520260895751347,2.1796705270663246,0.18817110729581882,0.9022328809207614,-0.2078582008305619,-0.922651025281217,0.5897732536440574,-0.1169852894996316,0.7143997644606782
2,808
Long eyelashes
14
33
2.113927
0.034522
O94979,Q99496,O94992,P49711,O60216,Q13724,Q969G3,P51532,Q12824,P21281,Q9Y619,Q6KC79,Q03164,Q6ZRS2
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
434,573,248,439,74,28,50,509,207,357,323,446,151,254
1267,74,434,248,1891,357,1220,439,509,935,151,207,28,832,881,1299,885,560,446,2083,254,1372,783,2620,50,2578,2500,1004,573,2020,1618,1203,323
0.06570166634344686,1.663681686992128,0.5897732536440574,0.8395044242627464,-0.2078582008305619,0.683197904709607,0.09626890734001688,0.5897732536440574,0.5276425976297412,0.24960427184179984,1.12268648099708,0.9650771179059916,2.701813618906324,0.31116761353809186,0.28036976760383425,0.06570166634344686,0.28036976760383425,0.4966235150833113,0.5897732536440574,-0.32851996753944923,0.8395044242627464,0.035168185019498165,0.34199761865011447,-1.0976762202817745,2.0824413152506027,-0.981166329813051,-0.8051101382923185,0.21887131973311785,0.4966235150833113,-0.268261621890122,-0.056227562452395775,0.12686969850312335,0.7456315061409986
2,808
Pre mrna binding
7
17
2.11225
0.034665
P14866,Q00839,Q9BWF3,P26368,Q6P2Q9,P22626,P62995
Functions
GO Molecular function
msigdb_gomf
249,289,103,284,522,137,122
1399,499,249,665,137,284,1488,122,289,1163,1361,1108,522,2333,1909,103,1010
0.004668675743301722,0.5276425976297412,0.8395044242627464,0.40375335457087713,1.154292705937211,0.7768929689687475,-0.025796646179977383,1.2492775721878775,0.7768929689687475,0.12686969850312335,0.035168185019498165,0.157503833136453,0.5276425976297412,-0.5680616178685269,-0.2078582008305619,1.3763068074774625,0.21887131973311785
2,808
Abnormal circulating carbohydrate concentration
6
34
2.110519
0.034814
Q70HW3,Q5JRX3,O95831,Q9Y6M9,O43676,Q8N183
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
3,37,8,178,206,118
206,2061,495,2415,861,8,1883,1884,2681,2346,2615,2289,921,1217,821,1277,669,1577,826,1035,1105,37,3,2382,118,2308,276,1605,2749,2314,1616,2201,1738,178
0.9650771179059916,-0.32851996753944923,0.5276425976297412,-0.686906887210775,0.28036976760383425,5.599558398962463,-0.2078582008305619,-0.2078582008305619,-1.443251300169841,-0.5978320623763692,-1.0976762202817745,-0.5382522425398498,0.24960427184179984,0.09626890734001688,0.31116761353809186,0.06570166634344686,0.40375335457087713,-0.056227562452395775,0.31116761353809186,0.18817110729581882,0.157503833136453,2.3747748432232223,7.59192311238963,-0.6275632860710119,1.2809941384574963,-0.5382522425398498,0.8081839940334757,-0.056227562452395775,-2.118822245842012,-0.5382522425398498,-0.056227562452395775,-0.41863107325011994,-0.1169852894996316,1.0595579576867387
2,808
Negative regulation of mrna catabolic process
12
27
2.109345
0.034915
O60506,Q92804,Q00839,Q14011,Q08211,Q14103,P67809,P07910,Q99729,Q9H074,P35637,P16989
Processes and pathways
GO Biological process
msigdb_gobp
247,38,289,70,470,291,362,356,255,60,182,91
2762,247,1625,356,1478,91,182,362,674,289,1649,470,1163,678,70,291,1715,1656,1176,780,2534,1601,38,255,60,1198,535
-2.2572634211995095,0.8395044242627464,-0.08662385171865596,0.683197904709607,-0.025796646179977383,1.4399830962547482,1.0280359415852773,0.683197904709607,0.40375335457087713,0.7768929689687475,-0.08662385171865596,0.558692568069395,0.12686969850312335,0.40375335457087713,1.6957426054920703,0.7768929689687475,-0.1169852894996316,-0.08662385171865596,0.12686969850312335,0.34199761865011447,-0.8933290661726461,-0.056227562452395775,2.3747748432232223,0.8395044242627464,1.8886425503706181,0.12686969850312335,0.5276425976297412
2,808
Maturation of 5 8s rrna
19
26
2.105256
0.035269
Q13868,P42285,O75691,Q9NQT5,Q9Y3B9,Q9BXY0,O60287,Q06265,Q9H9Y2,O00541,Q9GZL7,Q8N9T8,Q9Y4W2,Q15050,O95478,P78316,Q9Y2P8,Q15024,Q8IY81
Processes and pathways
GO Biological process
msigdb_gobp
773,627,497,424,301,170,51,311,735,806,731,343,489,339,708,595,906,241,525
806,51,497,708,627,595,875,2114,311,773,1103,241,339,2043,1851,2333,525,343,1244,170,731,735,424,906,301,489
0.31116761353809186,2.017743302585445,0.5276425976297412,0.37285959438321625,0.4346787153903801,0.46563549531765897,0.28036976760383425,-0.35859411376495665,0.7456315061409986,0.34199761865011447,0.157503833136453,0.8708541043895993,0.7143997644606782,-0.298409052876078,-0.17760269665740328,-0.5680616178685269,0.5276425976297412,0.7143997644606782,0.09626890734001688,1.0911081847929223,0.37285959438321625,0.37285959438321625,0.6208844836851677,0.28036976760383425,0.7768929689687475,0.558692568069395
2,808
Chromatin organization
60
152
2.103786
0.035397
Q13547,P11387,Q9H7B4,Q13363,P62805,P16403,P51532,Q9NQZ2,Q96L91,Q03164,Q9UKK9,Q99496,O96028,Q00839,O75367,Q96GM5,Q6PL18,P06748,Q969G3,O94776,O95696,P52926,Q99733,P33993,P29375,Q9NXR7,Q9NRL2,P17096,P45973,Q86X55,P49711,O95983,Q9H4L7,Q9UIG0,Q8WXX5,Q96SB4,Q99543,Q9P0M6,Q96T88,Q12824,Q96T23,O14646,Q8WXI9,P16402,Q5VTR2,O75531,P55209,P07305,Q8NB78,Q9BQ67,P83916,Q86YP4,Q15022,P61964,P07910,Q9UK61,Q9BYW2,Q15020,Q14839,Q6ZRS2
Processes and pathways
GO Biological process
msigdb_gobp
516,622,5,135,629,503,509,159,693,151,431,573,282,289,403,166,165,662,50,541,542,52,57,550,181,63,202,437,438,341,439,75,614,738,478,482,82,617,726,207,725,326,225,709,95,583,93,587,368,234,469,524,518,238,356,262,529,637,636,254
1135,1267,326,1072,2316,2513,2060,808,809,1557,403,583,2063,541,2458,542,75,2065,282,1213,2398,1396,662,587,356,2146,622,1142,1808,709,503,437,1342,866,1027,1219,1569,181,550,438,987,2696,1417,439,1287,509,826,1419,52,93,238,629,469,289,2039,1507,2114,151,876,207,1295,1102,1162,993,1510,1426,1166,135,516,719,636,2617,637,518,834,2264,945,1364,1301,95,2467,2186,165,1438,254,1720,1849,1368,2405,341,524,2307,840,368,1372,1855,225,478,1967,955,1308,2012,1857,1053,50,1309,789,166,693,1445,482,1191,725,2389,726,573,82,2128,57,234,2131,2093,529,2758,614,5,1609,2195,159,2313,202,1612,63,617,800,902,1066,738,262,431,1263,2362,1923,1204,2581,852,853,1741,1265,1266,2527,2024
0.12686969850312335,0.06570166634344686,0.7143997644606782,0.157503833136453,-0.5680616178685269,-0.8639647040355153,-0.32851996753944923,0.31116761353809186,0.31116761353809186,-0.056227562452395775,0.6208844836851677,0.46563549531765897,-0.32851996753944923,0.4966235150833113,-0.7460900042688136,0.4966235150833113,1.663681686992128,-0.32851996753944923,0.7768929689687475,0.09626890734001688,-0.6572549942161213,0.004668675743301722,0.40375335457087713,0.46563549531765897,0.683197904709607,-0.38863123561707724,0.4346787153903801,0.12686969850312335,-0.17760269665740328,0.37285959438321625,0.5276425976297412,0.5897732536440574,0.035168185019498165,0.28036976760383425,0.18817110729581882,0.09626890734001688,-0.056227562452395775,1.0280359415852773,0.4966235150833113,0.5897732536440574,0.21887131973311785,-1.5572143805270398,0.004668675743301722,0.5897732536440574,0.06570166634344686,0.5276425976297412,0.31116761353809186,0.004668675743301722,2.017743302585445,1.4399830962547482,0.8708541043895993,0.4346787153903801,0.558692568069395,0.7768929689687475,-0.298409052876078,-0.025796646179977383,-0.35859411376495665,1.12268648099708,0.28036976760383425,0.9650771179059916,0.06570166634344686,0.157503833136453,0.12686969850312335,0.21887131973311785,-0.025796646179977383,0.004668675743301722,0.12686969850312335,1.185926720770312,0.5276425976297412,0.37285959438321625,0.4346787153903801,-1.0976762202817745,0.4346787153903801,0.5276425976297412,0.31116761353809186,-0.5084042217553665,0.24960427184179984,0.035168185019498165,0.06570166634344686,1.4399830962547482,-0.7460900042688136,-0.41863107325011994,1.0911081847929223,0.004668675743301722,0.8395044242627464,-0.1169852894996316,-0.17760269665740328,0.035168185019498165,-0.6572549942161213,0.7143997644606782,0.5276425976297412,-0.5382522425398498,0.31116761353809186,0.683197904709607,0.035168185019498165,-0.17760269665740328,0.9336406021056348,0.558692568069395,-0.2380779229637603,0.24960427184179984,0.06570166634344686,-0.268261621890122,-0.17760269665740328,0.18817110729581882,2.0824413152506027,0.06570166634344686,0.34199761865011447,1.0911081847929223,0.40375335457087713,0.004668675743301722,0.558692568069395,0.12686969850312335,0.37285959438321625,-0.6275632860710119,0.37285959438321625,0.4966235150833113,1.5996372357081536,-0.35859411376495665,1.9208805629344818,0.9022328809207614,-0.35859411376495665,-0.32851996753944923,0.5276425976297412,-2.201975058706754,0.46563549531765897,5.772234941394142,-0.056227562452395775,-0.41863107325011994,1.12268648099708,-0.5382522425398498,0.9965422799663923,-0.056227562452395775,1.8242415276513662,0.46563549531765897,0.34199761865011447,0.28036976760383425,0.18817110729581882,0.37285959438321625,0.8395044242627464,0.6208844836851677,0.09626890734001688,-0.5978320623763692,-0.2078582008305619,0.12686969850312335,-0.981166329813051,0.31116761353809186,0.31116761353809186,-0.1169852894996316,0.09626890734001688,0.09626890734001688,-0.8639647040355153,-0.268261621890122
2,808
Mecp2 and associated rett syndrome
13
21
2.098525
0.035859
Q13547,P52597,P49711,Q08211,Q05086,P08069,P42345,Q14353,P67809,Q8NAV1,P21359,P35637,P31943
Processes and pathways
WikiPathways
msigdb_wp
516,133,439,470,410,546,822,389,362,688,818,182,92
1333,546,1565,818,92,182,822,439,826,133,1226,362,410,470,1163,2117,516,389,688,1191,1203
0.035168185019498165,0.4966235150833113,-0.056227562452395775,0.31116761353809186,1.4399830962547482,1.0280359415852773,0.31116761353809186,0.5897732536440574,0.31116761353809186,1.185926720770312,0.09626890734001688,0.683197904709607,0.6208844836851677,0.558692568069395,0.12686969850312335,-0.35859411376495665,0.5276425976297412,0.6520260895751347,0.40375335457087713,0.12686969850312335,0.12686969850312335
2,808
Ercc6 csb and ehmt2 g9a positively regulate rrna expression
6
11
2.090469
0.036576
Q13547,O95983,Q86YP4,O94776,Q8WXI9,Q14839
Processes and pathways
Reactome Pathways
msigdb_reactome
516,75,524,541,225,636
541,75,1808,629,1510,1166,516,636,524,225,1308
0.4966235150833113,1.663681686992128,-0.17760269665740328,0.4346787153903801,-0.025796646179977383,0.12686969850312335,0.5276425976297412,0.4346787153903801,0.5276425976297412,0.9336406021056348,0.06570166634344686
2,808
Osteoblast differentiation
13
37
2.087068
0.036882
O60506,Q00839,O76021,Q13951,Q9BQG0,P38159,Q86V81,Q9NY93,Q9NR30,P07910,Q9P2E9,P55265,P62841
Processes and pathways
GO Biological process
msigdb_gobp
247,289,382,196,346,106,340,161,486,356,429,334,335
805,247,2174,748,382,1745,975,356,1144,665,818,1024,871,2255,1572,106,1348,1944,1153,334,1502,335,1293,1506,289,470,196,1176,1659,340,1376,2385,346,647,486,161,429
0.31116761353809186,0.8395044242627464,-0.41863107325011994,0.34199761865011447,0.6520260895751347,-0.14731164812392894,0.21887131973311785,0.683197904709607,0.12686969850312335,0.40375335457087713,0.31116761353809186,0.18817110729581882,0.28036976760383425,-0.5084042217553665,-0.056227562452395775,1.3445088870289958,0.035168185019498165,-0.2380779229637603,0.12686969850312335,0.7143997644606782,-0.025796646179977383,0.7143997644606782,0.06570166634344686,-0.025796646179977383,0.7768929689687475,0.558692568069395,0.9965422799663923,0.12686969850312335,-0.08662385171865596,0.7143997644606782,0.035168185019498165,-0.6275632860710119,0.7143997644606782,0.4346787153903801,0.558692568069395,1.12268648099708,0.6208844836851677
2,808
Abnormality of skeletal maturation
32
85
2.073358
0.038139
Q8WWQ0,Q6ZRS2,Q13363,O95831,Q06124,P19447,P51532,Q9UJX6,Q03164,P51812,Q969N2,Q15813,O96028,P18074,Q96GM5,P08069,Q9BUK6,Q969G3,Q9NW13,P52926,Q7Z2Z2,Q9Y619,O75179,Q6KC79,Q8IY37,O60216,Q12824,Q99575,Q15022,Q92889,Q9BYW2,Q9Y4P3
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
395,254,135,8,15,267,509,430,151,148,567,559,282,406,166,546,49,50,455,52,314,323,56,446,605,74,207,233,518,119,529,536
2762,1874,1463,1267,74,56,1686,2569,8,282,2722,1213,546,1985,2146,1339,1887,2460,406,267,1811,1407,924,669,1492,1150,1701,2074,509,826,1153,932,148,52,1351,593,2258,1645,1093,1094,151,15,1649,1038,207,135,2795,832,518,1105,2377,2156,559,446,2083,254,314,1240,2560,605,2667,1372,395,119,50,567,166,1781,1191,233,49,529,612,2272,2194,1677,455,800,1682,738,430,1203,1794,536,323
-2.2572634211995095,-0.2078582008305619,-0.025796646179977383,0.06570166634344686,1.663681686992128,1.953143430854237,-0.1169852894996316,-0.981166329813051,5.599558398962463,0.7768929689687475,-1.783438896118417,0.09626890734001688,0.4966235150833113,-0.268261621890122,-0.38863123561707724,0.035168185019498165,-0.2078582008305619,-0.7460900042688136,0.6208844836851677,0.8081839940334757,-0.17760269665740328,0.004668675743301722,0.24960427184179984,0.40375335457087713,-0.025796646179977383,0.12686969850312335,-0.1169852894996316,-0.32851996753944923,0.5276425976297412,0.31116761353809186,0.12686969850312335,0.24960427184179984,1.12268648099708,2.017743302585445,0.035168185019498165,0.46563549531765897,-0.5084042217553665,-0.08662385171865596,0.157503833136453,0.157503833136453,1.12268648099708,3.6292428778432244,-0.08662385171865596,0.18817110729581882,0.9650771179059916,1.185926720770312,-3.9737839708594738,0.31116761353809186,0.5276425976297412,0.157503833136453,-0.6275632860710119,-0.38863123561707724,0.4966235150833113,0.5897732536440574,-0.32851996753944923,0.8395044242627464,0.7456315061409986,0.09626890734001688,-0.9519302317950293,0.46563549531765897,-1.357388264627863,0.035168185019498165,0.6520260895751347,1.2809941384574963,2.0824413152506027,0.4966235150833113,1.0911081847929223,-0.14731164812392894,0.12686969850312335,0.9022328809207614,2.1472366342770832,0.5276425976297412,0.46563549531765897,-0.5084042217553665,-0.41863107325011994,-0.08662385171865596,0.5897732536440574,0.34199761865011447,-0.08662385171865596,0.37285959438321625,0.6208844836851677,0.12686969850312335,-0.14731164812392894,0.5276425976297412,0.7456315061409986
2,808
nuclear_punctae
32
72
2.071066
0.038353
P09012,P19784,P14866,P11388,P30876,Q13501,Q13523,P17480,Q9NYV4,P63000,Q96PK6,P38432,P56545,Q96GM5,P26368,Q9UBU9,P55769,P19387,Q9ULX6,Q15029,P24928,P83916,Q08211,P98179,P38159,P50995,Q15428,Q5BKZ1,Q9UPN9,O15042,Q16637,O95400
Localization
OpenCell Localization
opencell_localization
621,250,249,501,624,136,632,757,426,768,168,761,407,166,284,320,672,180,62,599,329,469,470,596,106,358,519,112,652,352,638,619
1206,2343,352,1465,2478,1557,2437,619,2320,621,1399,1022,501,1886,249,757,180,979,250,982,329,1342,866,284,624,1571,106,761,987,358,1290,2461,1997,672,407,1831,768,1358,1581,938,469,596,2261,470,876,1163,136,632,832,599,1515,519,638,883,112,1523,1306,1307,1669,1119,1311,166,168,1783,1005,1785,2196,1455,426,320,62,652
0.09626890734001688,-0.5978320623763692,0.683197904709607,-0.025796646179977383,-0.7756206036620558,-0.056227562452395775,-0.7165186604646431,0.4346787153903801,-0.5680616178685269,0.4346787153903801,0.004668675743301722,0.18817110729581882,0.5276425976297412,-0.2078582008305619,0.8395044242627464,0.34199761865011447,1.0280359415852773,0.21887131973311785,0.8395044242627464,0.21887131973311785,0.7143997644606782,0.035168185019498165,0.28036976760383425,0.7768929689687475,0.4346787153903801,-0.056227562452395775,1.3445088870289958,0.34199761865011447,0.21887131973311785,0.683197904709607,0.06570166634344686,-0.7460900042688136,-0.268261621890122,0.40375335457087713,0.6208844836851677,-0.17760269665740328,0.34199761865011447,0.035168185019498165,-0.056227562452395775,0.24960427184179984,0.558692568069395,0.46563549531765897,-0.5084042217553665,0.558692568069395,0.28036976760383425,0.12686969850312335,1.185926720770312,0.4346787153903801,0.31116761353809186,0.46563549531765897,-0.025796646179977383,0.5276425976297412,0.4346787153903801,0.28036976760383425,1.312737953942776,-0.025796646179977383,0.06570166634344686,0.06570166634344686,-0.08662385171865596,0.157503833136453,0.06570166634344686,1.0911081847929223,1.0911081847929223,-0.14731164812392894,0.21887131973311785,-0.14731164812392894,-0.41863107325011994,0.004668675743301722,0.6208844836851677,0.7456315061409986,1.8564295019872012,0.4346787153903801
2,808
Abnormality of limb epiphysis morphology
6
26
2.063603
0.039055
Q6ZRS2,O96028,Q13363,O95831,P82673,P51812
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
254,282,135,8,108,148
1463,1268,1686,2569,8,282,1339,2460,1340,2250,148,2258,108,135,1431,2265,254,2469,314,1054,2094,1862,1786,1737,2202,1794
-0.025796646179977383,0.06570166634344686,-0.1169852894996316,-0.981166329813051,5.599558398962463,0.7768929689687475,0.035168185019498165,-0.7460900042688136,0.035168185019498165,-0.5084042217553665,1.12268648099708,-0.5084042217553665,1.3445088870289958,1.185926720770312,0.004668675743301722,-0.5084042217553665,0.8395044242627464,-0.7460900042688136,0.7456315061409986,0.18817110729581882,-0.32851996753944923,-0.17760269665740328,-0.14731164812392894,-0.1169852894996316,-0.41863107325011994,-0.14731164812392894
2,808
Lncrna in canonical wnt signaling and colorectal cancer
6
11
2.062024
0.039205
P19784,P56545,Q00839,Q13363,Q9UJX6,P61978
Processes and pathways
WikiPathways
msigdb_wp
250,407,289,135,430,150
250,871,1762,407,150,1581,289,135,617,430,1204
0.8395044242627464,0.28036976760383425,-0.14731164812392894,0.6208844836851677,1.12268648099708,-0.056227562452395775,0.7768929689687475,1.185926720770312,0.46563549531765897,0.6208844836851677,0.12686969850312335
2,808
Vascular dilatation
12
64
2.059613
0.039436
Q5TBB1,P27635,P55011,Q06124,P61619,Q9UBS4,Q96PZ0,P42858,P01889,Q96PU5,P61978,P55265
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
391,228,361,15,269,400,53,24,23,25,150,334
1546,1686,1689,1801,2063,2284,2065,23,544,1935,2571,1339,664,1340,818,1811,228,867,2291,924,762,2371,1150,24,1350,1641,824,1351,361,334,269,150,1645,1093,1584,1161,15,1649,1295,1772,833,2377,391,2083,1238,2469,1240,2560,1054,1003,25,53,1004,529,1677,800,400,1199,1921,738,430,1457,909,536
-0.056227562452395775,-0.1169852894996316,-0.1169852894996316,-0.17760269665740328,-0.32851996753944923,-0.5382522425398498,-0.32851996753944923,2.8661831768006865,0.4966235150833113,-0.2380779229637603,-0.981166329813051,0.035168185019498165,0.40375335457087713,0.035168185019498165,0.31116761353809186,-0.17760269665740328,0.9022328809207614,0.28036976760383425,-0.5382522425398498,0.24960427184179984,0.34199761865011447,-0.6275632860710119,0.12686969850312335,2.8661831768006865,0.035168185019498165,-0.08662385171865596,0.31116761353809186,0.035168185019498165,0.683197904709607,0.7143997644606782,0.8081839940334757,1.12268648099708,-0.08662385171865596,0.157503833136453,-0.056227562452395775,0.12686969850312335,3.6292428778432244,-0.08662385171865596,0.06570166634344686,-0.14731164812392894,0.31116761353809186,-0.6275632860710119,0.6520260895751347,-0.32851996753944923,0.09626890734001688,-0.7460900042688136,0.09626890734001688,-0.9519302317950293,0.18817110729581882,0.21887131973311785,2.833264740413757,2.017743302585445,0.21887131973311785,0.5276425976297412,-0.08662385171865596,0.34199761865011447,0.6520260895751347,0.12686969850312335,-0.2078582008305619,0.37285959438321625,0.6208844836851677,0.004668675743301722,0.28036976760383425,0.5276425976297412
2,808
mRNA transport
26
66
2.055177
0.039862
Q16629,Q96PU8,P09651,P22626,Q8NI27,Q9BTX1,Q13838,O15504,Q9Y6M1,Q9UBU9,Q92945,Q96FV9,Q07955,Q9BW27,Q96ST2,Q8NFH4,Q9Y3Y2,Q8WYP5,Q9BY77,Q12769,P49792,P37198,P57740,Q08211,Q96EE3,Q09161
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
253,396,499,137,689,296,679,656,578,320,189,315,555,199,69,606,73,344,610,597,714,331,593,470,232,365
2138,1549,1551,656,860,1334,499,1142,137,1413,331,1028,1029,1223,714,1821,1947,593,2299,1707,1095,769,1649,555,470,365,597,1714,679,253,1112,779,1182,1720,951,1853,1525,1526,606,689,2487,1186,1001,344,1374,189,232,315,1122,396,1057,69,1248,296,1535,199,610,2358,1735,1198,320,1868,2525,73,1070,578
-0.38863123561707724,-0.056227562452395775,-0.056227562452395775,0.40375335457087713,0.28036976760383425,0.035168185019498165,0.5276425976297412,0.12686969850312335,1.154292705937211,0.004668675743301722,0.7143997644606782,0.18817110729581882,0.18817110729581882,0.09626890734001688,0.37285959438321625,-0.17760269665740328,-0.2380779229637603,0.46563549531765897,-0.5382522425398498,-0.1169852894996316,0.157503833136453,0.34199761865011447,-0.08662385171865596,0.4966235150833113,0.558692568069395,0.683197904709607,0.46563549531765897,-0.1169852894996316,0.40375335457087713,0.8395044242627464,0.157503833136453,0.34199761865011447,0.12686969850312335,-0.1169852894996316,0.24960427184179984,-0.17760269665740328,-0.025796646179977383,-0.025796646179977383,0.46563549531765897,0.40375335457087713,-0.7756206036620558,0.12686969850312335,0.21887131973311785,0.7143997644606782,0.035168185019498165,1.0280359415852773,0.9022328809207614,0.7456315061409986,0.157503833136453,0.6520260895751347,0.18817110729581882,1.7278291635665208,0.09626890734001688,0.7768929689687475,-0.025796646179977383,0.9965422799663923,0.46563549531765897,-0.5978320623763692,-0.1169852894996316,0.12686969850312335,0.7456315061409986,-0.17760269665740328,-0.8639647040355153,1.6957426054920703,0.18817110729581882,0.4966235150833113
2,808
Protein hydroxylation
6
13
2.050562
0.04031
Q96AY3,Q12797,O00469,O75718,Q92791,Q32P28
Processes and pathways
GO Biological process
msigdb_gobp
47,337,205,22,59,222
205,22,586,385,1161,337,1297,222,2467,59,47,608,2359
0.9650771179059916,2.8661831768006865,0.46563549531765897,0.6520260895751347,0.12686969850312335,0.7143997644606782,0.06570166634344686,0.9336406021056348,-0.7460900042688136,1.8886425503706181,2.1796705270663246,0.46563549531765897,-0.5978320623763692
2,808
Abnormal femoral neck head morphology
9
38
2.048743
0.040487
Q6ZRS2,Q99575,O95831,Q96HY6,Q96AY3,Q7Z2Z2,Q9Y619,O75718,P51812
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
254,233,8,167,47,314,323,22,148
1463,1686,2062,22,2063,8,544,917,2287,2770,1340,2250,867,763,1350,1701,148,361,2258,1957,1431,636,254,2469,314,1376,47,167,1054,233,2094,1862,1786,2051,1737,1794,1070,323
-0.025796646179977383,-0.1169852894996316,-0.32851996753944923,2.8661831768006865,-0.32851996753944923,5.599558398962463,0.4966235150833113,0.24960427184179984,-0.5382522425398498,-2.6683718860934924,0.035168185019498165,-0.5084042217553665,0.28036976760383425,0.34199761865011447,0.035168185019498165,-0.1169852894996316,1.12268648099708,0.683197904709607,-0.5084042217553665,-0.2380779229637603,0.004668675743301722,0.4346787153903801,0.8395044242627464,-0.7460900042688136,0.7456315061409986,0.035168185019498165,2.1796705270663246,1.0911081847929223,0.18817110729581882,0.9022328809207614,-0.32851996753944923,-0.17760269665740328,-0.14731164812392894,-0.298409052876078,-0.1169852894996316,-0.14731164812392894,0.18817110729581882,0.7456315061409986
2,808
Broad long bones
8
30
2.044386
0.040915
Q93008,P49711,O14936,P55011,Q15022,Q96PZ0,P42858,Q8WXI9
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
373,439,246,361,518,53,24,225
1546,246,1686,1689,2065,1340,1811,24,439,361,1038,1295,773,1772,1431,518,560,2469,1240,225,373,2126,1054,53,1384,1921,2020,1737,1457,1070
-0.056227562452395775,0.8395044242627464,-0.1169852894996316,-0.1169852894996316,-0.32851996753944923,0.035168185019498165,-0.17760269665740328,2.8661831768006865,0.5897732536440574,0.683197904709607,0.18817110729581882,0.06570166634344686,0.34199761865011447,-0.14731164812392894,0.004668675743301722,0.5276425976297412,0.4966235150833113,-0.7460900042688136,0.09626890734001688,0.9336406021056348,0.683197904709607,-0.35859411376495665,0.18817110729581882,2.017743302585445,0.035168185019498165,-0.2078582008305619,-0.268261621890122,-0.1169852894996316,0.004668675743301722,0.18817110729581882
2,808
Bromodomain-like superfamily [IPR036427]
8
14
2.043754
0.040978
Q8WWQ0,Q9NRL2,Q6PL18,Q9UIG0,P51532,O95696,Q9UPN9,Q03164
Sequence
InterPro Superfamily
interpro_homologous_superfamily
395,202,165,738,509,542,652,151
1930,542,866,509,151,1295,1426,165,1368,395,202,738,739,652
-0.2380779229637603,0.4966235150833113,0.28036976760383425,0.5276425976297412,1.12268648099708,0.06570166634344686,0.004668675743301722,1.0911081847929223,0.035168185019498165,0.6520260895751347,0.9965422799663923,0.37285959438321625,0.37285959438321625,0.4346787153903801
2,808
Bromodomain [IPR001487]
8
14
2.043754
0.040978
Q8WWQ0,Q9NRL2,Q6PL18,Q9UIG0,P51532,O95696,Q9UPN9,Q03164
Sequence
InterPro Domain
interpro_domain
395,202,165,738,509,542,652,151
1930,542,866,509,151,1295,1426,165,1368,395,202,738,739,652
-0.2380779229637603,0.4966235150833113,0.28036976760383425,0.5276425976297412,1.12268648099708,0.06570166634344686,0.004668675743301722,1.0911081847929223,0.035168185019498165,0.6520260895751347,0.9965422799663923,0.37285959438321625,0.37285959438321625,0.4346787153903801
2,808
Broad nasal tip
18
46
2.040746
0.041276
Q93008,O43292,Q6ZRS2,O14936,P49711,O95831,Q96GM5,Q6DKJ4,Q9Y4W2,P35573,Q969G3,P51532,Q15042,Q12824,P21281,Q8WXI9,P61978,P51812
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
373,305,254,246,439,8,166,560,489,268,50,509,186,207,357,225,150,148
1267,246,305,2100,1686,8,546,2584,1339,2770,357,2324,871,268,1757,1758,439,509,826,1419,148,2481,150,2260,207,1295,773,186,560,1438,254,1849,2469,997,1240,1372,225,373,50,166,2500,2358,1008,1384,2020,489
0.06570166634344686,0.8395044242627464,0.7456315061409986,-0.35859411376495665,-0.1169852894996316,5.599558398962463,0.4966235150833113,-1.0103589569207994,0.035168185019498165,-2.6683718860934924,0.683197904709607,-0.5680616178685269,0.28036976760383425,0.8081839940334757,-0.14731164812392894,-0.14731164812392894,0.5897732536440574,0.5276425976297412,0.31116761353809186,0.004668675743301722,1.12268648099708,-0.7756206036620558,1.12268648099708,-0.5084042217553665,0.9650771179059916,0.06570166634344686,0.34199761865011447,1.0280359415852773,0.4966235150833113,0.004668675743301722,0.8395044242627464,-0.17760269665740328,-0.7460900042688136,0.21887131973311785,0.09626890734001688,0.035168185019498165,0.9336406021056348,0.683197904709607,2.0824413152506027,1.0911081847929223,-0.8051101382923185,-0.5978320623763692,0.21887131973311785,0.035168185019498165,-0.268261621890122,0.558692568069395
2,808
Abnormality of the hypothalamus pituitary axis
20
64
2.038516
0.041498
Q8WWQ0,Q14746,Q8NI27,P48735,Q03164,Q9Y285,Q99496,Q15813,Q9BUK6,Q9NW13,Q969G3,Q7Z2Z2,Q8IY37,Q9BZH6,Q12824,Q96IJ6,O75874,P57740,Q92889,Q9UBS4
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
395,635,689,19,151,30,573,559,49,455,50,314,605,612,207,99,100,593,119,400
1874,1330,2343,1686,100,2506,1213,1985,1339,2460,1345,871,2177,1347,928,2073,19,1153,932,1290,593,2180,2258,1094,151,1649,1037,2262,207,832,833,635,1958,1515,559,683,1299,314,1850,605,1665,689,395,891,119,50,99,1003,1191,573,49,1447,612,1384,1735,2409,2165,455,800,400,2020,1618,30,1794
-0.2078582008305619,0.035168185019498165,-0.5978320623763692,-0.1169852894996316,1.3763068074774625,-0.8345582822732515,0.09626890734001688,-0.268261621890122,0.035168185019498165,-0.7460900042688136,0.035168185019498165,0.28036976760383425,-0.41863107325011994,0.035168185019498165,0.24960427184179984,-0.32851996753944923,2.9650707110154166,0.12686969850312335,0.24960427184179984,0.06570166634344686,0.46563549531765897,-0.41863107325011994,-0.5084042217553665,0.157503833136453,1.12268648099708,-0.08662385171865596,0.18817110729581882,-0.5084042217553665,0.9650771179059916,0.31116761353809186,0.31116761353809186,0.4346787153903801,-0.2380779229637603,-0.025796646179977383,0.4966235150833113,0.40375335457087713,0.06570166634344686,0.7456315061409986,-0.17760269665740328,0.46563549531765897,-0.08662385171865596,0.40375335457087713,0.6520260895751347,0.28036976760383425,1.2809941384574963,2.0824413152506027,1.4081315864034736,0.21887131973311785,0.12686969850312335,0.4966235150833113,2.1472366342770832,0.004668675743301722,0.46563549531765897,0.035168185019498165,-0.1169852894996316,-0.6572549942161213,-0.38863123561707724,0.5897732536440574,0.34199761865011447,0.6520260895751347,-0.268261621890122,-0.056227562452395775,2.5707228467689385,-0.14731164812392894
2,808
Abnormal sternum morphology
32
99
2.036513
0.041699
Q96S52,Q13363,O95831,Q9Y2W2,Q15555,Q06124,O75718,Q9UJX6,Q03164,P61978,P51812,Q969N2,P60953,O96028,Q6DKJ4,P08069,Q96AY3,Q9BUK6,Q9Y619,Q6KC79,P55795,O60216,Q9Y4R8,O00469,P24928,P53007,Q9NWH9,Q02750,Q15437,Q9BYW2,P55011,Q9Y4P3
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
397,135,8,280,273,15,22,430,151,150,148,567,408,282,560,546,47,49,323,446,195,74,350,205,329,467,376,109,111,529,361,536
1463,205,1469,74,1800,1686,2062,22,2569,8,282,544,2722,1935,1631,546,2459,2770,757,1340,818,921,1990,329,1221,2291,1812,924,2177,928,1152,826,1153,148,467,1351,361,195,593,408,150,1645,1708,1093,674,109,1161,151,15,1649,1038,135,2799,832,1957,2377,111,273,2378,1303,560,446,1438,2469,1904,1240,1723,1600,2270,567,1376,2578,47,2126,1781,1054,397,1006,1446,49,529,2358,2094,1008,1786,1677,2391,376,2020,738,430,1203,1619,1391,280,743,536,350,323
-0.025796646179977383,0.9650771179059916,-0.025796646179977383,1.663681686992128,-0.17760269665740328,-0.1169852894996316,-0.32851996753944923,2.8661831768006865,-0.981166329813051,5.599558398962463,0.7768929689687475,0.4966235150833113,-1.783438896118417,-0.2380779229637603,-0.08662385171865596,0.4966235150833113,-0.7460900042688136,-2.6683718860934924,0.34199761865011447,0.035168185019498165,0.31116761353809186,0.24960427184179984,-0.268261621890122,0.7143997644606782,0.09626890734001688,-0.5382522425398498,-0.17760269665740328,0.24960427184179984,-0.41863107325011994,0.24960427184179984,0.12686969850312335,0.31116761353809186,0.12686969850312335,1.12268648099708,0.558692568069395,0.035168185019498165,0.683197904709607,0.9965422799663923,0.46563549531765897,0.6208844836851677,1.12268648099708,-0.08662385171865596,-0.1169852894996316,0.157503833136453,0.40375335457087713,1.3445088870289958,0.12686969850312335,1.12268648099708,3.6292428778432244,-0.08662385171865596,0.18817110729581882,1.185926720770312,-4.389523644940029,0.31116761353809186,-0.2380779229637603,-0.6275632860710119,1.312737953942776,0.8081839940334757,-0.6275632860710119,0.06570166634344686,0.4966235150833113,0.5897732536440574,0.004668675743301722,-0.7460900042688136,-0.2078582008305619,0.09626890734001688,-0.1169852894996316,-0.056227562452395775,-0.5084042217553665,0.4966235150833113,0.035168185019498165,-0.981166329813051,2.1796705270663246,-0.35859411376495665,-0.14731164812392894,0.18817110729581882,0.6520260895751347,0.21887131973311785,0.004668675743301722,2.1472366342770832,0.5276425976297412,-0.5978320623763692,-0.32851996753944923,0.21887131973311785,-0.14731164812392894,-0.08662385171865596,-0.6275632860710119,0.683197904709607,-0.268261621890122,0.37285959438321625,0.6208844836851677,0.12686969850312335,-0.056227562452395775,0.035168185019498165,0.8081839940334757,0.37285959438321625,0.5276425976297412,0.7143997644606782,0.7456315061409986
2,808
Sumoylation
25
69
2.031668
0.042187
Q13547,P11387,P11388,Q02880,Q13363,P62805,Q92841,Q9BTX1,P61978,Q99496,O15504,P06748,P17844,Q9BW27,P45973,Q8NFH4,O60216,P49792,Q12769,P37198,P57740,Q14676,Q96EE3,Q15022,P07910
Processes and pathways
Reactome Pathways
msigdb_reactome
516,622,501,512,135,629,691,296,150,573,656,662,665,199,438,606,74,714,597,331,593,366,232,518,356
656,74,1334,1213,662,356,1020,622,501,1886,1142,665,1027,1894,1413,331,438,1030,1223,714,1821,1947,593,150,629,1583,512,597,1296,1426,1166,135,516,366,832,518,945,1182,951,1597,2235,1525,1665,1526,606,1186,1001,783,1374,1308,691,232,1003,1247,1191,573,2014,1248,296,1535,199,2195,1256,1735,2393,1261,1868,1203,907
0.40375335457087713,1.663681686992128,0.035168185019498165,0.09626890734001688,0.40375335457087713,0.683197904709607,0.18817110729581882,0.4346787153903801,0.5276425976297412,-0.2078582008305619,0.12686969850312335,0.40375335457087713,0.18817110729581882,-0.2078582008305619,0.004668675743301722,0.7143997644606782,0.5897732536440574,0.18817110729581882,0.09626890734001688,0.37285959438321625,-0.17760269665740328,-0.2380779229637603,0.46563549531765897,1.12268648099708,0.4346787153903801,-0.056227562452395775,0.5276425976297412,0.46563549531765897,0.06570166634344686,0.004668675743301722,0.12686969850312335,1.185926720770312,0.5276425976297412,0.683197904709607,0.31116761353809186,0.5276425976297412,0.24960427184179984,0.12686969850312335,0.24960427184179984,-0.056227562452395775,-0.47851783636555056,-0.025796646179977383,-0.08662385171865596,-0.025796646179977383,0.46563549531765897,0.12686969850312335,0.21887131973311785,0.34199761865011447,0.035168185019498165,0.06570166634344686,0.40375335457087713,0.9022328809207614,0.21887131973311785,0.09626890734001688,0.12686969850312335,0.4966235150833113,-0.268261621890122,0.09626890734001688,0.7768929689687475,-0.025796646179977383,0.9965422799663923,-0.41863107325011994,0.09626890734001688,-0.1169852894996316,-0.6275632860710119,0.09626890734001688,-0.17760269665740328,0.12686969850312335,0.28036976760383425
2,808
Dna templated transcription elongation
17
38
2.025348
0.042832
Q15061,O94992,Q8WX92,P18074,Q00839,Q9GZS3,O14776,Q16186,Q5BKZ1,Q86V81,P19447,Q9BYW2,Q96FV9,Q9NYV4,Q6IA86,P18615,P35269
Processes and pathways
GO Biological process
msigdb_gobp
251,248,607,406,289,530,492,444,112,340,267,529,315,426,561,464,626
1206,492,1465,1468,248,2458,406,464,267,871,626,1760,289,1714,679,1771,251,2003,444,883,112,779,561,1237,2186,1720,340,2085,1241,840,607,1673,315,529,1785,530,426,1265
0.09626890734001688,0.5276425976297412,-0.025796646179977383,-0.025796646179977383,0.8395044242627464,-0.7460900042688136,0.6208844836851677,0.558692568069395,0.8081839940334757,0.28036976760383425,0.4346787153903801,-0.14731164812392894,0.7768929689687475,-0.1169852894996316,0.40375335457087713,-0.14731164812392894,0.8395044242627464,-0.268261621890122,0.5897732536440574,0.28036976760383425,1.312737953942776,0.34199761865011447,0.4966235150833113,0.09626890734001688,-0.41863107325011994,-0.1169852894996316,0.7143997644606782,-0.32851996753944923,0.09626890734001688,0.31116761353809186,0.46563549531765897,-0.08662385171865596,0.7456315061409986,0.5276425976297412,-0.14731164812392894,0.5276425976297412,0.6208844836851677,0.09626890734001688
2,808
Sumoylation of chromatin organization proteins
13
35
2.023664
0.043005
Q9BW27,Q13547,Q99496,P45973,Q8NFH4,P57740,P62805,Q96EE3,O15504,P37198,Q15022,Q12769,Q9BTX1
Processes and pathways
Reactome Pathways
msigdb_reactome
199,516,573,438,606,593,629,232,656,331,518,597,296
656,1334,1142,1413,331,438,1223,714,1821,1947,593,629,1583,597,516,518,1182,951,1597,1525,1526,606,1186,1001,1374,1308,232,573,1248,296,1535,199,2195,1735,1868
0.40375335457087713,0.035168185019498165,0.12686969850312335,0.004668675743301722,0.7143997644606782,0.5897732536440574,0.09626890734001688,0.37285959438321625,-0.17760269665740328,-0.2380779229637603,0.46563549531765897,0.4346787153903801,-0.056227562452395775,0.46563549531765897,0.5276425976297412,0.5276425976297412,0.12686969850312335,0.24960427184179984,-0.056227562452395775,-0.025796646179977383,-0.025796646179977383,0.46563549531765897,0.12686969850312335,0.21887131973311785,0.035168185019498165,0.06570166634344686,0.9022328809207614,0.4966235150833113,0.09626890734001688,0.7768929689687475,-0.025796646179977383,0.9965422799663923,-0.41863107325011994,-0.1169852894996316,-0.17760269665740328
2,808
Type i collagen synthesis in the context of osteogenesis imperfecta
6
11
2.022913
0.043082
P13674,Q96AY3,O00469,O75718,Q8NBJ5,Q32P28
Processes and pathways
WikiPathways
msigdb_wp
385,47,205,22,475,222
205,22,586,385,1990,1289,1161,222,2265,475,47
0.9650771179059916,2.8661831768006865,0.46563549531765897,0.6520260895751347,-0.268261621890122,0.06570166634344686,0.12686969850312335,0.9336406021056348,-0.5084042217553665,0.558692568069395,2.1796705270663246
2,808
Primary mitochondrial disease
14
77
2.022733
0.043101
Q70HW3,Q6DKK2,O95831,Q9Y2R9,O95299,Q9Y6M9,Q5JPH6,Q9BQP7,P47985,Q9H9J2,O43676,Q8N183,Q9BQT8,Q00059
Drugs and Diseases
Protein Atlas Disease involvement
protein_atlas_disease_involvement
3,163,8,145,105,178,223,113,173,243,206,118,96,219
2058,2413,206,1331,2317,2061,495,2415,861,1558,1559,105,8,1211,2681,2346,1398,663,1695,1887,436,2289,1891,1217,2322,821,1490,1029,1760,173,1945,1704,360,1094,2000,219,312,1178,1774,223,413,2355,2607,163,1365,3,2738,562,118,2236,952,2357,276,1312,1381,1605,2130,2048,113,96,1536,1254,243,2314,2219,2095,2339,2166,2201,2202,2727,145,1927,1738,1872,1545,178
-0.32851996753944923,-0.686906887210775,0.9650771179059916,0.035168185019498165,-0.5680616178685269,-0.32851996753944923,0.5276425976297412,-0.686906887210775,0.28036976760383425,-0.056227562452395775,-0.056227562452395775,1.3445088870289958,5.599558398962463,0.09626890734001688,-1.443251300169841,-0.5978320623763692,0.004668675743301722,0.40375335457087713,-0.1169852894996316,-0.2078582008305619,0.5897732536440574,-0.5382522425398498,-0.2078582008305619,0.09626890734001688,-0.5680616178685269,0.31116761353809186,-0.025796646179977383,0.18817110729581882,-0.14731164812392894,1.0595579576867387,-0.2380779229637603,-0.1169852894996316,0.683197904709607,0.157503833136453,-0.268261621890122,0.9336406021056348,0.7456315061409986,0.12686969850312335,-0.14731164812392894,0.9336406021056348,0.6208844836851677,-0.5978320623763692,-1.068613481619668,1.0911081847929223,0.035168185019498165,7.59192311238963,-1.9796304626012016,0.4966235150833113,1.2809941384574963,-0.47851783636555056,0.24960427184179984,-0.5978320623763692,0.8081839940334757,0.06570166634344686,0.035168185019498165,-0.056227562452395775,-0.35859411376495665,-0.298409052876078,1.312737953942776,1.4399830962547482,-0.025796646179977383,0.09626890734001688,0.8708541043895993,-0.5382522425398498,-0.448593362815423,-0.32851996753944923,-0.5680616178685269,-0.38863123561707724,-0.41863107325011994,-0.41863107325011994,-1.8396557492791603,1.154292705937211,-0.2078582008305619,-0.1169852894996316,-0.17760269665740328,-0.025796646179977383,1.0595579576867387
2,808
Nucleic acid phosphodiester bond hydrolysis
24
79
2.013432
0.044069
O95831,Q14692,P19447,Q9UQ84,Q9NQT5,P18074,Q9BQG2,Q9Y3B8,P52926,Q06265,Q8N9T8,Q99598,Q6UN15,Q15050,Q9Y4W2,O00273,Q99575,Q15024,Q09161,Q9BQP7,Q9H9J2,Q92889,Q96C86,Q9H0D6
Processes and pathways
GO Biological process
msigdb_gobp
8,272,267,21,424,406,42,43,52,311,343,483,210,339,489,457,233,241,365,113,243,119,526,257
1205,457,2694,1744,497,1801,2505,1746,916,8,406,267,1893,820,1408,985,764,827,52,595,938,2114,311,1037,365,1586,1587,1651,1230,2116,773,1103,272,241,339,683,1111,2043,2123,1044,210,1659,1851,2559,2333,2384,2708,1777,343,952,954,956,119,1244,526,2388,233,483,2048,42,113,613,257,243,965,1970,424,577,1127,903,2221,1200,2622,21,741,906,43,909,489
0.09626890734001688,0.558692568069395,-1.5572143805270398,-0.14731164812392894,0.5276425976297412,-0.17760269665740328,-0.8345582822732515,-0.14731164812392894,0.24960427184179984,5.599558398962463,0.6208844836851677,0.8081839940334757,-0.2078582008305619,0.31116761353809186,0.004668675743301722,0.21887131973311785,0.34199761865011447,0.31116761353809186,2.017743302585445,0.46563549531765897,0.24960427184179984,-0.35859411376495665,0.7456315061409986,0.18817110729581882,0.683197904709607,-0.056227562452395775,-0.056227562452395775,-0.08662385171865596,0.09626890734001688,-0.35859411376495665,0.34199761865011447,0.157503833136453,0.8081839940334757,0.8708541043895993,0.7143997644606782,0.40375335457087713,0.157503833136453,-0.298409052876078,-0.35859411376495665,0.18817110729581882,0.9650771179059916,-0.08662385171865596,-0.17760269665740328,-0.9519302317950293,-0.5680616178685269,-0.6275632860710119,-1.6139791591871209,-0.14731164812392894,0.7143997644606782,0.24960427184179984,0.24960427184179984,0.24960427184179984,1.2809941384574963,0.09626890734001688,0.5276425976297412,-0.6275632860710119,0.9022328809207614,0.558692568069395,-0.298409052876078,2.2446102741548635,1.312737953942776,0.46563549531765897,0.8395044242627464,0.8708541043895993,0.24960427184179984,-0.2380779229637603,0.6208844836851677,0.4966235150833113,0.157503833136453,0.28036976760383425,-0.448593362815423,0.12686969850312335,-1.0976762202817745,2.9650707110154166,0.37285959438321625,0.28036976760383425,2.2446102741548635,0.28036976760383425,0.558692568069395
2,808
Dental malocclusion
7
20
2.009825
0.04445
P60953,Q02750,Q06124,Q12797,P21281,P61978,P51812
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
408,109,15,337,357,150,148
1135,2030,1339,357,1340,924,148,408,150,1093,109,15,2422,337,2377,1438,1853,1598,738,536
0.12686969850312335,-0.298409052876078,0.035168185019498165,0.683197904709607,0.035168185019498165,0.24960427184179984,1.12268648099708,0.6208844836851677,1.12268648099708,0.157503833136453,1.3445088870289958,3.6292428778432244,-0.686906887210775,0.7143997644606782,-0.6275632860710119,0.004668675743301722,-0.17760269665740328,-0.056227562452395775,0.37285959438321625,0.5276425976297412
2,808
Macule
13
56
2.002255
0.045257
Q8WWQ0,Q9Y2W2,Q02750,Q06124,Q15437,P19447,P52926,Q96PZ0,P42858,P01889,Q92889,P55011,P55265
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
395,280,109,15,111,267,52,53,24,23,119,361,334
1546,1467,859,1800,539,1689,2063,916,2065,23,544,662,1339,2399,406,267,818,921,1811,867,822,24,2073,1290,52,1291,361,334,1645,109,15,2787,1295,1772,1655,1515,111,2596,1109,2009,2469,1240,2560,395,119,53,1191,1004,1447,2194,614,2165,577,1921,1457,280
-0.056227562452395775,-0.025796646179977383,0.28036976760383425,-0.17760269665740328,0.4966235150833113,-0.1169852894996316,-0.32851996753944923,0.24960427184179984,-0.32851996753944923,2.8661831768006865,0.4966235150833113,0.40375335457087713,0.035168185019498165,-0.6572549942161213,0.6208844836851677,0.8081839940334757,0.31116761353809186,0.24960427184179984,-0.17760269665740328,0.28036976760383425,0.31116761353809186,2.8661831768006865,-0.32851996753944923,0.06570166634344686,2.017743302585445,0.06570166634344686,0.683197904709607,0.7143997644606782,-0.08662385171865596,1.3445088870289958,3.6292428778432244,-3.4472512921585343,0.06570166634344686,-0.14731164812392894,-0.08662385171865596,-0.025796646179977383,1.312737953942776,-1.0395078899761159,0.157503833136453,-0.268261621890122,-0.7460900042688136,0.09626890734001688,-0.9519302317950293,0.6520260895751347,1.2809941384574963,2.017743302585445,0.12686969850312335,0.21887131973311785,0.004668675743301722,-0.41863107325011994,0.46563549531765897,-0.38863123561707724,0.4966235150833113,-0.2078582008305619,0.004668675743301722,0.8081839940334757
2,808
Single stranded dna binding
19
51
2.001762
0.04531
P11387,Q9Y2W2,P09651,P22626,Q9P2K5,Q00839,Q96FZ2,P15927,P33993,P36776,P53999,Q96I24,Q9GZR2,Q08211,Q6NSI4,P67809,Q04837,Q92889,Q9NYB0
Functions
GO Molecular function
msigdb_gomf
622,280,499,137,171,289,41,547,550,669,194,480,613,470,521,362,239,119,399
1473,1213,1564,499,1985,1632,622,547,1937,137,1487,1219,1894,1569,1345,1280,550,669,1029,2073,1282,1287,2516,194,1091,717,362,2260,289,239,470,2303,1717,995,521,956,119,1780,41,480,1605,1247,2014,1859,613,2549,1453,399,171,280,909
-0.025796646179977383,0.09626890734001688,-0.056227562452395775,0.5276425976297412,-0.268261621890122,-0.08662385171865596,0.4346787153903801,0.4966235150833113,-0.2380779229637603,1.154292705937211,-0.025796646179977383,0.09626890734001688,-0.2078582008305619,-0.056227562452395775,0.035168185019498165,0.06570166634344686,0.4966235150833113,0.40375335457087713,0.18817110729581882,-0.32851996753944923,0.06570166634344686,0.06570166634344686,-0.8639647040355153,0.9965422799663923,0.157503833136453,0.37285959438321625,0.683197904709607,-0.5084042217553665,0.7768929689687475,0.8708541043895993,0.558692568069395,-0.5382522425398498,-0.1169852894996316,0.21887131973311785,0.5276425976297412,0.24960427184179984,1.2809941384574963,-0.14731164812392894,2.2446102741548635,0.558692568069395,-0.056227562452395775,0.09626890734001688,-0.268261621890122,-0.17760269665740328,0.46563549531765897,-0.922651025281217,0.004668675743301722,0.6520260895751347,1.0911081847929223,0.8081839940334757,0.28036976760383425
2,808
Round face
6
16
1.991327
0.046445
Q8WWQ0,P82673,Q03164,Q15022,O75718,Q32P28
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
395,108,151,518,22,222
22,544,2030,1339,1347,1348,1704,108,151,832,518,222,1303,395,2243,2202
2.8661831768006865,0.4966235150833113,-0.298409052876078,0.035168185019498165,0.035168185019498165,0.035168185019498165,-0.1169852894996316,1.3445088870289958,1.12268648099708,0.31116761353809186,0.5276425976297412,0.9336406021056348,0.06570166634344686,0.6520260895751347,-0.47851783636555056,-0.41863107325011994
2,808
Pi3kakt signaling pathway
16
28
1.984539
0.047196
P28482,P13807,Q07820,P63218,P63151,Q9NWH9,Q02750,P23588,P11802,P08069,Q16822,P14625,P42345,Q16513,P30154,P63000
Processes and pathways
WikiPathways
msigdb_wp
867,306,513,937,594,376,109,819,283,546,996,502,822,880,87,768
1213,1691,1275,546,1475,283,306,502,819,1342,867,1221,87,2253,822,1226,1504,768,594,937,109,513,993,1171,880,1177,996,376
0.09626890734001688,-0.1169852894996316,0.06570166634344686,0.4966235150833113,-0.025796646179977383,0.7768929689687475,0.7456315061409986,0.5276425976297412,0.31116761353809186,0.035168185019498165,0.28036976760383425,0.09626890734001688,1.5037658050599132,-0.5084042217553665,0.31116761353809186,0.09626890734001688,-0.025796646179977383,0.34199761865011447,0.46563549531765897,0.24960427184179984,1.3445088870289958,0.5276425976297412,0.21887131973311785,0.12686969850312335,0.28036976760383425,0.12686969850312335,0.21887131973311785,0.683197904709607
2,808
RNA metabolism protein
51
90
1.984165
0.047237
O43390,O60506,P10155,Q5T3I0,Q9NQZ2,Q13428,P61978,Q9BVJ6,Q8IWX8,O75127,O75683,Q92804,Q96SI9,Q9UNW9,O00567,Q9Y6M1,Q00341,Q9UBU9,Q92945,P05455,Q9NQ55,Q9H074,P35637,Q13601,P37108,O00541,P21399,Q9NV06,Q9Y3Y2,Q9H814,Q15366,Q9BY77,Q96I24,Q9Y3A2,Q86V81,Q12906,Q14690,Q5T8P6,P55265,Q8TDN6,Q9H583,P78316,Q9Y2P8,Q9Y2X3,Q8NEF9,Q71RC2,Q6PKG0,Q4G0J3,O75616,Q9BQ75,Q9BTE6
Functions
Panther Protein class
panther_protein_class
128,247,755,950,159,944,150,420,415,402,404,38,572,701,655,578,940,320,189,918,319,60,182,313,670,806,549,203,73,734,995,610,480,742,340,208,598,472,334,370,898,595,906,907,242,781,780,883,354,792,794
1549,806,972,655,128,2630,1467,247,402,354,404,918,755,549,982,182,670,2508,1222,334,2258,150,595,1583,940,2261,208,2116,944,313,1653,1430,598,1515,1717,995,883,950,472,2305,780,2380,781,1851,340,415,2597,1441,1725,242,370,2045,1307,1601,38,189,1780,480,1122,1123,572,2389,1004,792,794,1534,420,610,60,898,1193,734,1451,319,159,203,1065,2392,1198,320,1262,2525,701,906,907,742,1794,73,1327,578
-0.056227562452395775,0.31116761353809186,0.21887131973311785,0.40375335457087713,1.2175883881471963,-1.1556750417424753,-0.025796646179977383,0.8395044242627464,0.6208844836851677,0.683197904709607,0.6208844836851677,0.24960427184179984,0.34199761865011447,0.4966235150833113,0.21887131973311785,1.0280359415852773,0.40375335457087713,-0.8345582822732515,0.09626890734001688,0.7143997644606782,-0.5084042217553665,1.12268648099708,0.46563549531765897,-0.056227562452395775,0.24960427184179984,-0.5084042217553665,0.9650771179059916,-0.35859411376495665,0.24960427184179984,0.7456315061409986,-0.08662385171865596,0.004668675743301722,0.46563549531765897,-0.025796646179977383,-0.1169852894996316,0.21887131973311785,0.28036976760383425,0.24960427184179984,0.558692568069395,-0.5382522425398498,0.34199761865011447,-0.6275632860710119,0.34199761865011447,-0.17760269665740328,0.7143997644606782,0.6208844836851677,-1.0395078899761159,0.004668675743301722,-0.1169852894996316,0.8708541043895993,0.683197904709607,-0.298409052876078,0.06570166634344686,-0.056227562452395775,2.3747748432232223,1.0280359415852773,-0.14731164812392894,0.558692568069395,0.157503833136453,0.157503833136453,0.4966235150833113,-0.6275632860710119,0.21887131973311785,0.34199761865011447,0.34199761865011447,-0.025796646179977383,0.6208844836851677,0.46563549531765897,1.8886425503706181,0.28036976760383425,0.12686969850312335,0.37285959438321625,0.004668675743301722,0.7456315061409986,1.12268648099708,0.9965422799663923,0.18817110729581882,-0.6275632860710119,0.12686969850312335,0.7456315061409986,0.09626890734001688,-0.8639647040355153,0.40375335457087713,0.28036976760383425,0.28036976760383425,0.37285959438321625,-0.14731164812392894,1.6957426054920703,0.06570166634344686,0.4966235150833113
2,808
Concanavalin A-like lectin/glucanase domain superfamily [IPR013320]
10
16
1.98333
0.047331
P27797,O15344,Q00839,P27824,Q14258,Q9BUJ2,P19474,Q1KMD3,P17931,P50851
Sequence
InterPro Superfamily
interpro_homologous_superfamily
215,304,289,590,338,645,85,116,504,552
304,1560,504,85,215,590,1575,552,289,2352,677,338,116,954,2159,645
0.7456315061409986,-0.056227562452395775,0.5276425976297412,1.5356967553836633,0.9336406021056348,0.46563549531765897,-0.056227562452395775,0.4966235150833113,0.7768929689687475,-0.5978320623763692,0.40375335457087713,0.7143997644606782,1.2809941384574963,0.24960427184179984,-0.38863123561707724,0.4346787153903801
2,808
Fatigue
14
77
1.972843
0.048513
Q15165,Q70HW3,P27797,Q9H3L0,Q92804,Q07021,Q13501,Q9NWH9,P43243,Q6UN15,Q92889,P19447,P01889,P35637
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
2,3,215,200,38,312,136,376,286,210,119,267,23,182
1874,1329,2169,2317,859,1979,23,2722,1213,2699,1563,662,1935,2781,2417,545,499,1339,2723,1695,1144,406,267,818,921,1405,215,2531,1490,871,182,2480,2441,2371,1347,1897,286,2073,1944,358,1290,2075,1764,2180,1584,1767,941,312,1163,1167,136,1513,1957,878,1655,2,683,1299,1774,1237,210,1438,3,1188,38,119,567,1605,200,1195,376,1197,2551,2096,2199,704,2024
-0.2078582008305619,0.035168185019498165,-0.41863107325011994,-0.5680616178685269,0.28036976760383425,-0.268261621890122,2.8661831768006865,-1.783438896118417,0.09626890734001688,-1.5856145428378061,-0.056227562452395775,0.40375335457087713,-0.2380779229637603,-3.1273192334184325,-0.686906887210775,0.4966235150833113,0.5276425976297412,0.035168185019498165,-1.8115638240110032,-0.1169852894996316,0.12686969850312335,0.6208844836851677,0.8081839940334757,0.31116761353809186,0.24960427184179984,0.004668675743301722,0.9336406021056348,-0.8933290661726461,-0.025796646179977383,0.28036976760383425,1.0280359415852773,-0.7756206036620558,-0.7165186604646431,-0.6275632860710119,0.035168185019498165,-0.2078582008305619,0.7768929689687475,-0.32851996753944923,-0.2380779229637603,0.683197904709607,0.06570166634344686,-0.32851996753944923,-0.14731164812392894,-0.41863107325011994,-0.056227562452395775,-0.14731164812392894,0.24960427184179984,0.7456315061409986,0.12686969850312335,0.12686969850312335,1.185926720770312,-0.025796646179977383,-0.2380779229637603,0.28036976760383425,-0.08662385171865596,8.624354780633901,0.40375335457087713,0.06570166634344686,-0.14731164812392894,0.09626890734001688,0.9650771179059916,0.004668675743301722,7.59192311238963,0.12686969850312335,2.3747748432232223,1.2809941384574963,0.4966235150833113,-0.056227562452395775,0.9965422799663923,0.12686969850312335,0.683197904709607,0.12686969850312335,-0.922651025281217,-0.32851996753944923,-0.41863107325011994,0.40375335457087713,-0.268261621890122
2,808
Dna packaging
11
79
1.972586
0.048543
Q9NRL2,Q9H7B4,Q13363,O95831,Q9BQ67,O95983,O43823,P52926,P55209,Q99733,Q9ULX6
Processes and pathways
GO Biological process
msigdb_gobp
202,5,135,8,234,75,78,52,93,57,62
1135,2316,2060,78,808,809,403,583,1473,8,75,1213,2145,662,587,2146,501,1142,1808,709,503,1342,866,1027,1219,550,2349,1417,439,1287,826,52,2461,93,629,2039,1102,1162,1510,1426,135,516,2617,1773,637,1233,834,1364,1301,2186,2675,2307,2235,840,1855,478,1967,955,789,482,1191,725,2128,57,1676,234,2758,5,2313,202,1612,1453,617,738,262,1068,62,852,2024
0.12686969850312335,-0.5680616178685269,-0.32851996753944923,1.631646524525365,0.31116761353809186,0.31116761353809186,0.6208844836851677,0.46563549531765897,-0.025796646179977383,5.599558398962463,1.663681686992128,0.09626890734001688,-0.38863123561707724,0.40375335457087713,0.46563549531765897,-0.38863123561707724,0.5276425976297412,0.12686969850312335,-0.17760269665740328,0.37285959438321625,0.5276425976297412,0.035168185019498165,0.28036976760383425,0.18817110729581882,0.09626890734001688,0.4966235150833113,-0.5978320623763692,0.004668675743301722,0.5897732536440574,0.06570166634344686,0.31116761353809186,2.017743302585445,-0.7460900042688136,1.4399830962547482,0.4346787153903801,-0.298409052876078,0.157503833136453,0.12686969850312335,-0.025796646179977383,0.004668675743301722,1.185926720770312,0.5276425976297412,-1.0976762202817745,-0.14731164812392894,0.4346787153903801,0.09626890734001688,0.31116761353809186,0.035168185019498165,0.06570166634344686,-0.41863107325011994,-1.386047238947879,-0.5382522425398498,-0.47851783636555056,0.31116761353809186,-0.17760269665740328,0.558692568069395,-0.2380779229637603,0.24960427184179984,0.34199761865011447,0.558692568069395,0.12686969850312335,0.37285959438321625,-0.35859411376495665,1.9208805629344818,-0.08662385171865596,0.9022328809207614,-2.201975058706754,5.772234941394142,-0.5382522425398498,0.9965422799663923,-0.056227562452395775,0.004668675743301722,0.46563549531765897,0.37285959438321625,0.8395044242627464,0.18817110729581882,1.8564295019872012,0.31116761353809186,-0.268261621890122
2,808
Predicted membrane proteins
123
472
4.690743
0.000003
Q9NS69,Q9Y282,Q99595,O60830,Q15392,Q70HW3,Q5BJF2,Q96ES6,Q8NHS3,Q567V2,Q9UIQ6,P53985,Q96G23,P30519,Q8WTV0,O43676,Q9Y487,Q9H061,Q8IXU6,O15173,Q5SR56,Q9NPR9,O75844,Q8N511,Q92804,Q16850,Q5VW38,O60725,Q8IV08,O43772,P09601,O15118,Q14108,Q8NCC3,P42892,Q9HD20,Q86XL3,Q06481,Q06136,O75306,Q8NBX0,O14936,P43307,Q9Y2R0,O43169,P15260,Q9C0H2,Q9H1E5,O95197,Q15800,O75964,Q9BQE5,P04439,P55899,Q8N2A8,Q9Y287,P01889,Q93050,O15260,Q6ZT21,Q9UBX3,Q96SK2,Q9NR28,O00461,O15270,Q9P2W9,Q9Y619,P11117,P08183,Q8NE01,Q9Y679,Q14739,Q07820,P42858,Q9Y6C9,Q96PC5,Q15904,Q9Y624,Q7L0J3,Q9NQC3,Q9HD45,O75976,O43493,Q3SXM5,O00264,Q8NF37,Q96A26,Q9BZF1,O95772,P62942,Q15629,Q6P4Q7,Q9Y262,P51003,P10321,Q8TCT9,P11717,Q13505,Q99523,Q96S97,Q92896,P35573,P35080,Q99943,Q07954,P42356,O43657,Q8TB61,Q96N66,Q9H4I3,Q01650,P50402,P04844,Q9UKR5,Q9HDC9,Q96FV9,P51648,Q12907,P37268,Q6RW13,P31350,O15344,Q969M3
Functions
Protein Atlas Protein class
protein_atlas_protein_class
5,6,8,9,10,11,14,19,20,23,25,26,27,30,37,39,41,48,50,51,53,54,56,60,65,69,71,72,73,75,79,82,84,85,86,99,107,111,113,115,122,119,124,126,127,132,144,145,146,152,154,158,160,163,164,174,167,170,176,179,188,191,202,200,204,211,212,206,205,224,233,232,231,228,244,242,239,249,254,266,265,268,276,278,282,293,296,307,300,302,310,311,320,315,312,324,321,330,337,342,353,361,360,377,374,373,370,393,407,421,415,413,410,423,437,434,425,426,444,448,443,440,461
1543,2735,1544,2699,282,200,2129,2449,2217,1024,2017,1545,1911,2656,2293,1860,516,119,82,868,51,802,176,1483,204,440,1758,127,617,1273,1809,276,370,2450,39,1227,75,1648,689,1228,1427,2657,72,9,2173,2132,115,841,1229,2358,2758,1326,987,2663,1652,56,871,2468,154,268,561,2295,1548,911,2587,1028,1383,1654,1486,146,2258,2588,537,2078,1959,300,538,915,876,2021,1280,167,660,451,2770,160,807,410,1030,1708,2221,2176,1488,1553,205,917,2419,723,79,2605,312,562,206,2623,724,990,321,953,1434,1184,132,1331,583,991,1389,2471,1187,1815,1768,992,2084,1086,2769,2228,993,564,30,1233,443,2307,1715,755,360,361,487,1088,444,541,1819,373,818,228,86,124,1038,542,1879,1133,1662,413,664,315,2089,425,665,2035,1929,620,26,1502,2542,1341,163,2527,1822,1194,1503,2716,1294,2477,2423,302,1140,1725,642,415,788,1243,789,113,1782,111,644,231,374,2796,2044,524,2647,731,2765,2774,426,2635,697,2272,1510,2148,1344,330,2099,1304,84,527,1146,2562,506,894,232,548,2197,2722,1833,2462,734,670,2046,2775,764,10,310,1935,1456,152,239,572,1575,2401,69,896,278,932,2047,1731,1007,699,2314,23,14,2105,2048,1577,1515,490,507,53,1936,1891,2752,793,71,2342,2786,2201,2579,856,311,1734,448,1892,1056,1153,674,179,1736,11,898,1009,254,826,2279,1307,2205,1520,1579,1308,2316,107,1309,73,2686,2782,767,1459,768,50,628,969,970,971,2053,164,1207,60,2370,2208,2482,1681,1523,933,122,2779,85,224,530,293,20,531,393,2729,901,2552,324,1793,37,702,1409,1525,1258,460,2407,1840,2109,1463,589,1413,1011,1527,532,65,353,170,1109,461,1315,1012,794,2371,296,650,2709,2059,1360,903,19,434,27,2511,1110,678,590,1362,2725,407,1842,242,2060,493,904,342,191,773,1796,1531,337,533,1213,8,1112,905,377,2248,158,2564,2565,2004,1216,1415,494,977,2799,1015,978,307,144,2287,1742,2288,2761,48,2772,683,145,2440,1469,2711,1165,1261,2515,421,1533,2375,2165,1534,99,265,437,1944,1220,54,266,202,2167,5,1070,1172,834,981,2674,2069,1222,2712,1020,712,1073,2465,2798,2289,211,534,1372,1536,778,188,713,982,2351,2730,2555,25,423,2444,866,779,2171,320,717,2127,6,174,1022,2681,2290,126,1423,1853,2013,1078,1804,1595,1541,41,1376,1953,593,801,212,249,1701,233,244,1755
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2,812
Lysosome
26
49
4.636503
0.000004
Q8NHS3,P08236,O75503,P06865,P07858,P16278,Q9Y487,Q93050,P06280,P10253,Q9UMR5,P10619,P50897,P11717,O15118,P11117,P54802,Q14108,Q8NCC3,P04062,O14773,P07602,Q15904,Q92572,Q9Y2T2,P17900
Processes and pathways
KEGG Pathways
msigdb_kegg
20,148,21,150,32,161,41,170,168,301,62,67,68,321,82,206,83,84,85,87,100,101,239,255,257,251
1702,558,2073,100,82,1274,1761,21,87,384,168,150,101,2080,32,148,2633,1031,301,67,206,990,321,811,161,251,1815,68,620,83,502,414,1447,1046,1346,84,239,85,20,255,170,337,1017,1020,1223,1908,62,257,41
-0.25395864506177507,0.5069552146823165,-0.457189555658307,2.0407291615321252,2.326399504773361,-0.031687014709587694,-0.28247580804102473,3.4527621477763786,2.24427219514418,0.7663817253435458,1.4676530771754677,1.565142433258028,2.0233395056563532,-0.457189555658307,3.16753088514317,1.5843918203314797,-1.0891391456991428,0.10219020816314191,0.9903454141911546,2.4704816361758035,1.3072002040011301,0.1285222344905635,0.9242813695324721,0.2580459451927195,1.4873187834566612,1.1409252165655943,-0.311161791776721,2.4547035837208413,0.43364725460652315,2.310095682444116,0.5791408457585902,0.7202683829276397,-0.11384263369455079,0.10219020816314191,-0.05891660926003703,2.277306408278314,1.1830609814557924,2.277306408278314,3.490212452974606,1.1409252165655943,1.4676530771754677,0.8797108080344074,0.1285222344905635,0.1285222344905635,0.022313356391112545,-0.34001843888349026,2.517478261676434,1.1409252165655943,2.8619031325793367
2,812
Vacuolar lumen
23
60
4.411511
0.00001
P68371,Q9BTY2,P08236,P06865,P07858,P16278,O00584,P06280,Q9UMR5,Q8NHP8,P10619,P50897,Q8IV08,Q92820,P11117,P54802,Q14108,P04062,O14773,P07602,P07437,Q9H7Z7,P17900
Localization
GO Cellular component
msigdb_gocc
261,143,148,150,32,161,159,168,62,64,67,68,73,76,206,83,84,87,100,101,246,125,251
558,159,100,1274,2021,87,384,168,150,2224,246,101,2080,32,808,148,301,67,206,1033,1126,811,161,251,1769,1610,541,1925,1190,68,1238,1566,620,1339,83,2142,641,414,261,1620,1000,1887,1346,84,1889,73,1105,64,76,1360,1531,2751,143,860,125,1587,1020,62,1800,2688
0.5069552146823165,1.4873187834566612,2.0407291615321252,-0.031687014709587694,-0.4276312314054814,2.24427219514418,0.7663817253435458,1.4676530771754677,1.565142433258028,-0.5469546575117772,1.1620412739234138,2.0233395056563532,-0.457189555658307,3.16753088514317,0.2580459451927195,1.5843918203314797,0.9903454141911546,2.4704816361758035,1.3072002040011301,0.10219020816314191,0.04908726812999223,0.2580459451927195,1.4873187834566612,1.1409252165655943,-0.28247580804102473,-0.19742355434165754,0.5311402316133299,-0.36904762138247893,0.022313356391112545,2.4547035837208413,-0.004610885946918551,-0.16940208304943802,0.43364725460652315,-0.05891660926003703,2.310095682444116,-0.48692821008242365,0.40895629462372546,0.7202683829276397,1.119711996032066,-0.19742355434165754,0.1285222344905635,-0.34001843888349026,-0.05891660926003703,2.277306408278314,-0.34001843888349026,2.3910188320042183,0.07571238201592677,2.486203187179412,2.358827559058653,-0.05891660926003703,-0.1415423442786107,-1.7742810257372263,1.6416545156496378,0.23242134673518783,1.809215592081938,-0.16940208304943802,0.1285222344905635,2.517478261676434,-0.28247580804102473,-1.260581097169132
2,812
Lysosomal lumen
18
33
4.163394
0.000031
P16278,Q8NHP8,P10619,P50897,O00584,O14773,P07602,Q8IV08,P06280,P11117,P08236,P54802,P06865,Q14108,P04062,P17900,Q9UMR5,P07858
Localization
GO Cellular component
msigdb_gocc
161,64,67,68,159,100,101,73,168,206,148,83,150,84,87,251,62,32
558,159,100,1274,87,384,168,150,101,2080,32,808,148,301,67,206,1033,811,161,251,541,1925,68,83,414,1346,84,73,1105,64,860,1020,62
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2,812
Endoplasmic reticulum
97
407
4.118807
0.000038
P30536,P07099,Q9Y282,Q15392,Q5BJF2,O75503,Q9UQB8,Q96G23,P30519,Q9UMX5,O15173,O75844,P80303,Q8N511,O95881,P10619,Q16850,O60725,Q8IV08,P09601,O15118,Q14108,P04062,Q32P28,Q9HD20,Q86XL3,Q06481,Q15437,Q06136,Q92791,P43307,Q14257,P55735,Q9H2J4,Q9BTY2,P48449,O95197,Q15800,Q9BQE5,P13674,P04439,O00584,P01889,O15260,Q8NFQ8,O43852,O60506,O15270,Q9P2W9,O43390,Q9Y679,Q14739,P42858,Q96PC5,Q15904,Q7L0J3,Q01105,Q9NQC3,O75718,O43493,Q6P179,O00264,P39687,Q8NF37,Q9BZF1,O95772,P62942,Q15629,Q8NBJ4,P48723,P10321,Q8TCT9,Q9H6E4,O43865,Q9UHB9,Q99523,Q9H223,Q9Y217,Q02750,P35573,Q9UBS4,Q99943,Q8TB61,Q96AY3,Q96N66,P61916,P50402,P04844,Q9UKR5,Q9NZ08,P51648,Q12907,P37268,Q6RW13,Q969M3,Q92542,Q12955
Localization
GO Cellular component
msigdb_gocc
0,3,6,10,14,21,22,27,30,38,51,56,59,60,63,67,69,72,73,79,82,84,87,96,99,107,111,114,113,123,124,128,129,130,143,142,146,152,158,156,160,159,167,176,184,193,194,204,211,213,233,232,228,242,239,254,252,266,259,276,279,282,288,293,307,300,302,310,318,313,312,324,326,328,334,337,356,369,362,361,380,377,393,405,407,414,413,410,423,438,425,426,444,448,461,460,454
1543,2735,282,594,2129,159,1545,1911,2656,1860,450,82,51,802,176,1483,204,2603,1272,617,213,276,1274,193,328,2657,194,72,805,1810,1484,841,2758,519,21,2663,259,56,2468,561,1277,873,1955,1704,1028,912,1383,146,2588,1279,1384,537,913,2078,1959,300,874,63,876,690,2021,167,2770,87,160,1707,807,410,1030,1386,1764,3,750,2137,1961,79,1657,312,67,2301,2302,156,1492,1436,752,583,991,2589,1389,2471,584,1871,785,882,1968,2084,2606,1714,1969,2727,2027,2264,540,2472,2180,2228,885,1769,2181,1391,1921,2182,30,565,0,816,1234,1715,361,2230,487,2031,444,541,1819,288,501,228,124,2541,2592,2141,542,2265,142,313,820,2266,1133,693,1662,413,2231,664,729,2089,425,2035,923,1721,1192,1881,2090,620,1567,1502,2142,2392,1193,998,129,1194,2716,2543,1240,2576,2528,1342,2561,1884,2460,2094,1294,2477,414,1398,2037,2039,1295,1399,1504,1242,1723,2748,302,1400,1446,1140,59,2236,2313,2720,1622,642,252,362,1726,543,2577,113,111,2271,644,2479,524,731,2336,426,454,2635,1451,697,1887,473,1346,2099,1304,84,1146,128,2562,506,1933,232,2197,1051,1833,1728,2462,849,1151,2046,698,1675,2775,10,2341,930,114,310,1574,1935,152,239,69,96,1007,2314,14,2105,2048,793,2049,2342,2201,279,2579,448,1153,1998,1736,898,254,826,2279,2507,2205,1520,1579,107,1938,73,1521,767,628,2599,1207,60,2370,2208,2482,1681,1523,318,2509,1208,1105,2779,293,184,1462,393,2406,2552,2054,324,1059,771,1793,1107,1312,1525,460,1840,2109,1463,1011,532,123,1211,2058,461,1315,1012,794,650,2709,2059,405,1360,27,2511,974,706,1362,407,242,493,904,1013,2061,337,1112,858,377,158,606,1532,2565,2004,1216,143,977,2799,1015,307,1063,1742,2772,2320,356,130,1317,1261,326,2441,1019,1534,99,1944,1220,266,1369,2376,1070,2069,1746,2712,438,712,2465,2289,865,211,1422,1372,380,778,1588,982,334,2009,423,1951,866,38,1538,779,1225,22,369,6,718,2570,1853,2012,2013,1078,2466,1857,1753,593,1701,1807,233,1755,984
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2,812
Mental deterioration
35
90
3.9944
0.000065
Q9Y3I1,Q10713,P21964,P35637,Q9NXN4,Q8NHS3,P10644,O75503,P43243,Q03164,P06865,P36543,Q9BQE5,P22626,P16278,P61916,Q9Y287,Q9Y487,P18074,O95470,P31483,P50897,P21912,P03886,Q5JTZ9,O15118,P54802,Q14108,P04062,Q13501,Q06787,P07602,P42858,O75306,P17900
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
536,525,270,141,408,20,520,21,522,24,150,151,158,283,161,414,174,41,539,537,424,68,196,451,208,82,83,84,87,473,350,101,228,115,251
594,2017,82,1274,689,1428,2132,115,21,561,1654,537,1385,1280,451,87,784,150,101,2080,1489,989,1766,520,161,1916,251,539,2456,196,270,283,1128,2473,424,141,151,691,1130,228,522,663,68,1565,2560,83,2092,2142,414,1091,1447,24,961,695,350,1827,525,1450,473,1346,84,1050,2102,208,1995,2433,897,1998,2370,20,1409,1210,934,1633,740,2061,2630,158,1168,1848,408,1020,1173,1949,2698,1538,2675,174,536,41
0.45820991892635715,-0.4276312314054814,2.326399504773361,-0.031687014709587694,0.35918453124975014,-0.11384263369455079,-0.48692821008242365,1.8456202538155837,3.4527621477763786,0.5069552146823165,-0.2256084890274861,0.5311402316133299,-0.08630127296868081,-0.031687014709587694,0.6502352734037639,2.24427219514418,0.2835332284224711,1.565142433258028,2.0233395056563532,-0.457189555658307,-0.1415423442786107,0.1285222344905635,-0.28247580804102473,0.5552017244663052,1.4873187834566612,-0.36904762138247893,1.1409252165655943,0.5311402316133299,-0.7630370464216969,1.3478444644435112,1.098400788944567,1.0554810704738096,0.04908726812999223,-0.7946963348979321,0.6970401416277441,1.6416545156496378,1.565142433258028,0.35918453124975014,0.04908726812999223,1.2248145512604927,0.5552017244663052,0.38413580421459165,2.4547035837208413,-0.16940208304943802,-0.9234041685354025,2.310095682444116,-0.457189555658307,-0.48692821008242365,0.7202683829276397,0.07571238201592677,-0.11384263369455079,3.389598452737596,0.15470992714805706,0.35918453124975014,0.8347092158473343,-0.311161791776721,0.5552017244663052,-0.11384263369455079,0.6266565061101952,-0.05891660926003703,2.277306408278314,0.10219020816314191,-0.457189555658307,1.3072002040011301,-0.39825124132052653,-0.7315799679422195,0.2066580696947229,-0.39825124132052653,-0.6692630532977037,3.490212452974606,-0.08630127296868081,0.022313356391112545,0.1807547309326192,-0.19742355434165754,0.3341012059117994,-0.4276312314054814,-1.0555468822980754,1.5263971248405028,0.04908726812999223,-0.311161791776721,0.7433818990772783,0.1285222344905635,0.04908726812999223,-0.36904762138247893,-1.3663385868789217,-0.1415423442786107,-1.1912964858988957,1.4676530771754677,0.5552017244663052,2.8619031325793367
2,812
Peptide binding
31
69
3.915083
0.00009
P55786,Q15392,O15212,O43813,P40855,Q6P179,Q9UIQ6,O00264,P04439,O00505,Q01650,P55899,Q8WTV0,Q9Y287,Q92973,O00629,P01889,P52294,Q9NZ08,P21266,O60684,P61758,P30414,P10321,Q9UHB9,Q9NXR7,P42892,O14773,Q07954,Q9H7Z7,Q9BYT8
Functions
GO Molecular function
msigdb_gomf
386,10,517,518,521,279,25,282,160,31,415,163,37,174,295,42,167,43,438,177,185,446,442,312,334,210,86,100,374,125,397
282,909,31,42,100,517,1912,518,185,1548,167,160,1553,1387,2633,1031,312,1085,177,2606,2180,885,1660,442,565,1875,2390,521,86,1821,1500,1663,960,923,43,2233,386,163,2528,1294,446,1983,415,374,1827,1931,2193,1051,1572,764,10,279,1358,37,295,2409,652,2119,397,1469,125,552,210,438,334,1021,25,174,1424
1.0554810704738096,0.1807547309326192,3.16753088514317,2.803929621091696,2.0407291615321252,0.5552017244663052,-0.36904762138247893,0.5552017244663052,1.3881308939912163,-0.16940208304943802,1.4676530771754677,1.4873187834566612,-0.16940208304943802,-0.08630127296868081,-1.0891391456991428,0.10219020816314191,0.946407369350807,0.07571238201592677,1.447902119529762,-1.0221799869805437,-0.5168492233508618,0.2066580696947229,-0.2256084890274861,0.6736961261378334,0.5069552146823165,-0.34001843888349026,-0.7003227426014513,0.5552017244663052,2.2608201286194824,-0.311161791776721,-0.1415423442786107,-0.2256084890274861,0.15470992714805706,0.1807547309326192,2.789314221988835,-0.5469546575117772,0.7663817253435458,1.4873187834566612,-0.858631173481535,-0.031687014709587694,0.6736961261378334,-0.39825124132052653,0.7202683829276397,0.789268883456853,-0.311161791776721,-0.36904762138247893,-0.5168492233508618,0.10219020816314191,-0.16940208304943802,0.3088845403658546,4.4515440828239035,1.0769907617339176,-0.05891660926003703,3.0312962380643427,1.012159267293361,-0.7003227426014513,0.40895629462372546,-0.457189555658307,0.7663817253435458,-0.11384263369455079,1.809215592081938,0.5311402316133299,1.3072002040011301,0.6970401416277441,0.9020494934900769,0.1285222344905635,3.376851885313292,1.4676530771754677,-0.08630127296868081
2,812
Peptidase activity
31
102
3.857436
0.000115
Q99829,Q96FW1,P42785,P49721,O75976,Q6P179,Q9UIQ6,Q9UPU5,Q5JRX3,P09960,P07858,Q9HB40,Q8TEY7,Q96FZ2,P28072,O75844,P49720,Q8TCT9,P10619,P28074,Q99436,Q92820,P42892,Q96K76,Q16740,O14773,P20618,P28070,P60900,Q9BYT8,Q96RU2
Functions
GO Molecular function
msigdb_gomf
396,133,15,18,268,279,25,281,157,287,32,36,294,172,45,56,314,324,67,70,199,76,86,216,220,100,102,110,120,397,395
985,1481,100,1179,617,2356,2219,56,268,1864,1028,660,2022,32,287,67,2689,919,1085,2589,102,1439,1288,110,45,70,2497,1770,2182,2797,1088,1037,488,15,86,1090,819,314,18,2267,1134,567,2233,620,2091,386,120,2576,1140,2706,525,1623,1932,762,1833,220,966,1788,157,1516,279,855,700,826,1580,324,294,460,1011,76,1211,605,935,738,1012,133,172,216,1316,395,1796,199,633,2061,858,396,578,397,653,1639,1585,479,36,580,2067,944,438,2704,25,281,1953,1596
0.1285222344905635,-0.1415423442786107,2.0407291615321252,0.022313356391112545,0.43364725460652315,-0.6692630532977037,-0.5469546575117772,2.533032514844444,1.098400788944567,-0.34001843888349026,0.10219020816314191,0.38413580421459165,-0.4276312314054814,3.16753088514317,1.0338708607112133,2.4704816361758035,-1.29558638215688,0.1807547309326192,0.07571238201592677,-0.9890357013357498,2.005881846159429,-0.11384263369455079,-0.031687014709587694,1.899680038524244,2.759934875525814,2.4229764762472206,-0.8265602308855787,-0.28247580804102473,-0.5168492233508618,-3.774897071094452,0.07571238201592677,0.10219020816314191,0.6029587324284209,3.937751240269287,2.2608201286194824,0.07571238201592677,0.2580459451927195,0.946407369350807,3.539634851198567,-0.5772466087129535,0.04908726812999223,0.5069552146823165,-0.5469546575117772,0.43364725460652315,-0.457189555658307,0.7663817253435458,1.8274547643749006,-0.9561113158015919,0.04908726812999223,-1.4381012368155113,0.5552017244663052,-0.19742355434165754,-0.36904762138247893,0.3088845403658546,-0.311161791776721,1.2661922382132038,0.15470992714805706,-0.28247580804102473,1.5263971248405028,-0.1415423442786107,1.0769907617339176,0.23242134673518783,0.35918453124975014,0.2580459451927195,-0.16940208304943802,0.9242813695324721,1.012159267293361,0.6502352734037639,0.1285222344905635,2.358827559058653,0.022313356391112545,0.45820991892635715,0.1807547309326192,0.3341012059117994,0.1285222344905635,1.679431285350743,1.4676530771754677,1.2867420568988635,-0.031687014709587694,0.7663817253435458,-0.28247580804102473,1.3478444644435112,0.43364725460652315,-0.4276312314054814,0.23242134673518783,0.7663817253435458,0.5069552146823165,0.7663817253435458,0.40895629462372546,-0.19742355434165754,-0.16940208304943802,0.6266565061101952,3.0588916001916124,0.5069552146823165,-0.4276312314054814,0.1807547309326192,0.6970401416277441,-1.4020919554916431,3.376851885313292,1.0769907617339176,-0.36904762138247893,-0.16940208304943802
2,812
Transporter activity
34
155
3.711403
0.000206
P30536,Q9NS69,Q99595,O60830,Q70HW3,P21796,Q9C0H2,P45880,Q96ES6,Q8NHS3,P36543,P53985,O75964,Q8WTV0,O43676,Q9Y487,Q93050,Q8IXU6,O15173,Q5SR56,Q9UBX3,Q9H2D1,O43772,Q9Y619,O15118,P08183,P04062,Q8NE01,Q9HD20,Q07820,O75306,P47985,Q9Y6M9,P17900
Functions
GO Molecular function
msigdb_gomf
0,5,8,9,11,13,144,17,19,20,151,26,154,37,39,41,170,50,51,53,188,61,75,212,82,205,87,224,99,231,115,236,258,251
2071,1268,2449,2018,516,82,51,2450,39,1274,75,1648,9,2173,2357,115,2536,949,2077,2328,154,1548,1486,1957,2258,1029,875,1385,1280,451,87,1030,1708,2221,2177,2224,1553,1710,205,917,2419,2331,2623,953,1434,1184,991,251,2572,1187,1608,920,563,13,882,1086,2702,993,1919,0,1233,2574,755,1188,151,541,691,17,236,2646,820,1662,665,471,2233,1239,26,1502,1341,2527,2500,502,1294,414,1725,2425,415,1243,231,1344,1511,894,331,2197,764,1456,1991,2401,1731,53,2786,1835,2579,856,311,11,1009,254,2279,50,1523,933,224,530,20,393,37,2109,2484,170,19,2511,1842,1464,533,8,858,396,2117,2799,1162,307,1063,144,2772,61,2440,2375,2165,99,5,1073,188,713,982,1223,656,866,1590,636,41,1176,212,908,258
-0.457189555658307,-0.031687014709587694,-0.7630370464216969,-0.4276312314054814,0.5552017244663052,2.326399504773361,2.6252145052389237,-0.7630370464216969,2.933293974683996,-0.031687014709587694,2.358827559058653,-0.2256084890274861,4.51024026447363,-0.5168492233508618,-0.6692630532977037,1.8456202538155837,-0.8909116443167836,0.15470992714805706,-0.457189555658307,-0.6383986218099443,1.5458110822803104,-0.16940208304943802,-0.1415423442786107,-0.39825124132052653,-0.5772466087129535,0.10219020816314191,0.2066580696947229,-0.08630127296868081,-0.031687014709587694,0.6502352734037639,2.24427219514418,0.10219020816314191,-0.25395864506177507,-0.5469546575117772,-0.5168492233508618,-0.5469546575117772,-0.16940208304943802,-0.25395864506177507,1.3072002040011301,0.1807547309326192,-0.7315799679422195,-0.6383986218099443,-1.0555468822980754,0.15470992714805706,-0.11384263369455079,0.022313356391112545,0.1285222344905635,1.1409252165655943,-0.9561113158015919,0.022313356391112545,-0.19742355434165754,0.1807547309326192,0.5069552146823165,3.948903861103401,0.2066580696947229,0.07571238201592677,-1.4020919554916431,0.1285222344905635,-0.36904762138247893,5.472379812321296,-0.004610885946918551,-0.9561113158015919,0.3088845403658546,0.022313356391112545,1.565142433258028,0.5311402316133299,0.35918453124975014,3.539634851198567,1.1830609814557924,-1.1229595856058519,0.2580459451927195,-0.2256084890274861,0.38413580421459165,0.6266565061101952,-0.5469546575117772,-0.004610885946918551,3.3640668856918023,-0.1415423442786107,-0.05891660926003703,-0.858631173481535,-0.8265602308855787,0.5791408457585902,-0.031687014709587694,0.7202683829276397,-0.25395864506177507,-0.7315799679422195,0.7202683829276397,-0.004610885946918551,1.2248145512604927,-0.05891660926003703,-0.1415423442786107,0.2066580696947229,0.9020494934900769,-0.5168492233508618,0.3088845403658546,-0.11384263369455079,-0.39825124132052653,-0.7003227426014513,-0.25395864506177507,2.5793664440470323,-2.702906874607414,-0.311161791776721,-0.9561113158015919,0.23242134673518783,0.9684284143189831,4.176415817828502,0.1285222344905635,1.1409252165655943,-0.5772466087129535,2.6403908305985557,-0.1415423442786107,0.1807547309326192,1.245549991515183,0.5552017244663052,3.490212452974606,0.7663817253435458,3.0312962380643427,-0.457189555658307,-0.7946963348979321,1.4676530771754677,3.539634851198567,-0.8265602308855787,-0.311161791776721,-0.11384263369455079,0.5552017244663052,4.519940897786278,0.23242134673518783,0.7663817253435458,-0.457189555658307,-3.9471181580065227,0.04908726812999223,0.9903454141911546,0.10219020816314191,1.6416545156496378,-2.1342282062168807,2.517478261676434,-0.7315799679422195,-0.6692630532977037,-0.48692821008242365,2.0753063950252693,4.736858349607043,0.10219020816314191,1.3881308939912163,0.35918453124975014,0.15470992714805706,0.022313356391112545,0.40895629462372546,0.23242134673518783,-0.16940208304943802,0.43364725460652315,2.8619031325793367,0.04908726812999223,1.3072002040011301,0.2066580696947229,1.1409252165655943
2,812
transporter
15
56
3.652285
0.00026
P55735,O00505,P53985,Q9HD45,Q99595,O60830,O00629,P52294,Q8NFH4,O43772,Q9Y619,Q567V2,O60684,P57740,Q9H2D1
Functions
Panther Protein class
panther_protein_class
129,31,26,265,8,9,42,43,240,75,212,23,185,284,61
909,31,42,2073,1546,1600,720,1274,75,185,9,950,1329,1875,1235,820,1663,923,43,2233,1239,26,1616,1042,129,284,1294,415,505,1051,670,23,2786,1578,971,240,1793,1358,2407,295,2463,679,533,8,905,2583,1903,61,635,265,2167,2568,2555,1749,1754,212
0.1807547309326192,3.16753088514317,2.803929621091696,-0.457189555658307,-0.16940208304943802,-0.19742355434165754,0.3341012059117994,-0.031687014709587694,2.358827559058653,1.3881308939912163,4.51024026447363,0.15470992714805706,-0.05891660926003703,-0.34001843888349026,-0.004610885946918551,0.2580459451927195,-0.2256084890274861,0.1807547309326192,2.789314221988835,-0.5469546575117772,-0.004610885946918551,3.3640668856918023,-0.19742355434165754,0.10219020816314191,1.7168950201979138,1.0554810704738096,-0.031687014709587694,0.7202683829276397,0.5791408457585902,0.10219020816314191,0.38413580421459165,3.4149771349732063,-2.702906874607414,-0.16940208304943802,0.15470992714805706,1.1830609814557924,-0.28247580804102473,-0.05891660926003703,-0.7003227426014513,1.012159267293361,-0.7630370464216969,0.38413580421459165,0.5552017244663052,4.519940897786278,0.2066580696947229,-0.9561113158015919,-0.34001843888349026,2.517478261676434,0.43364725460652315,1.119711996032066,-0.48692821008242365,-0.9234041685354025,-0.8909116443167836,-0.25395864506177507,-0.25395864506177507,1.3072002040011301
2,812
Hydrolase activity acting on glycosyl bonds
14
25
3.549754
0.000386
P16278,Q9BTY2,P06280,P35573,P10253,P54802,P08236,O75503,P06865,P04062,P17900,Q9NUJ1,O60502,Q8IW92
Functions
GO Molecular function
msigdb_gomf
161,143,168,361,301,83,148,21,150,87,251,90,29,94
558,840,29,21,87,384,168,150,2080,148,301,1658,500,161,251,1714,2472,564,361,83,1304,1933,94,143,90
0.5069552146823165,0.23242134673518783,3.2995578846231077,3.4527621477763786,2.24427219514418,0.7663817253435458,1.4676530771754677,1.565142433258028,-0.457189555658307,1.5843918203314797,0.9903454141911546,-0.2256084890274861,0.5791408457585902,1.4873187834566612,1.1409252165655943,-0.25395864506177507,-0.7946963348979321,0.5069552146823165,0.8120443818425275,2.310095682444116,-0.031687014709587694,-0.36904762138247893,2.1266741669465663,1.6416545156496378,2.16059271898911
2,812