term
stringlengths
2
121
overlap
int64
6
281
setsize
int64
7
499
score
float64
1.96
10.6
pval
float64
0
0.05
edge
stringlengths
41
1.97k
type
stringclasses
5 values
subtype
stringclasses
24 values
subtype_key
stringclasses
24 values
edge_idxs
stringlengths
11
1.17k
ann_idxs
stringlengths
19
2.31k
ann_vals
stringlengths
124
9.94k
sig_size
int64
2.2k
3.73k
Organic anion transport
22
49
2.891458
0.003835
Q9Y619,Q8TDW0,P41440,Q9Y6M7,O15439,Q9UJS0,Q96NB2,P12235,P07602,Q6NUK1,Q9UBX3,P12236,P53985,Q9BQT8,Q9H2J7,Q8TB61,Q08722,P04083,Q9HC21,Q15041,P30825,Q9NZJ7
Processes and pathways
GO Biological process
msigdb_gobp
131,522,269,536,278,547,413,553,48,441,56,565,202,75,204,83,347,599,488,499,120,256
700,278,950,819,1125,2375,1463,599,1054,1128,48,909,3051,553,565,2964,1912,836,120,269,1262,202,1338,1644,347,879,499,2765,617,441,1926,898,83,522,1065,413,665,731,75,204,769,488,256,56,2635,547,1458,131,536
0.4078989792455411,1.2550845585859318,0.19380682512269046,0.30204211533490194,0.06706796620069248,-0.6027955681655673,-0.1294642520833557,0.5406573616707142,0.11498437510700303,0.06706796620069248,2.9924252844164885,0.22497962854566572,-2.421230489514741,0.6128502332132403,0.5841039652256301,-1.250173600739404,-0.3516910545716578,0.2867278246330759,2.1709437111682344,1.304842448283804,-0.013858605375158513,1.6158927888366963,-0.06306863218986276,-0.21374796024844483,1.0374995229846102,0.255952511861343,0.6980630201166272,-0.8672923859684633,0.5260869274788118,0.7955852218137351,-0.3516910545716578,0.2404909124205327,2.525471026963564,0.655647241447091,0.11498437510700303,0.836774272954116,0.4673573625937165,0.39291854449948976,2.6836037582923837,1.6043080729323946,0.36281679569392605,0.7261314845184232,1.3784966610797764,2.8451205119843253,-0.7522128562660492,0.6271586509706826,-0.11278048268758513,2.0462929128969036,0.6414242418555797
3,069
Endoplasmic reticulum
69
194
2.866226
0.004154
P07237,P51648,O15269,Q03519,Q9H3N1,Q9UGP8,Q9HCU5,O43169,O96005,Q6NUQ4,Q9BT22,Q8NF37,O95197,Q9H6H4,P67809,O43852,Q8NHH9,Q9H3G5,Q9NQC3,Q9P2W9,Q15293,P84157,Q86UE4,P43307,Q00765,Q8WUJ1,Q9UM00,Q8TCJ2,O14681,Q9NZ01,P50402,Q96PC5,Q14257,O95470,O15260,Q99956,Q96A33,Q96KA5,O00264,Q96G23,Q9BUN8,Q70UQ0,Q15043,P13674,Q15800,Q8IV08,O15460,P37268,Q96A57,P27544,Q9UBM7,P51572,Q9P035,Q8N0U8,Q8TCT9,Q9Y680,Q92791,Q16850,Q6UW68,Q12981,Q99442,P48651,Q96F07,P21964,Q96GC9,Q96HY6,Q86XL3,Q96KC8,Q15041
Localization
Protein Atlas Subcellular
protein_atlas_subcellular_location_all
512,128,383,261,14,534,533,19,144,529,406,154,28,415,505,164,294,297,169,173,430,428,178,52,570,54,576,573,435,63,317,193,66,194,322,326,211,212,214,86,216,348,352,350,97,99,497,232,360,106,366,377,240,112,113,241,239,243,245,494,503,375,502,250,124,255,123,386,499
214,435,1599,867,322,383,497,19,1287,1053,1560,164,1012,819,989,2375,926,1602,28,1634,194,1014,144,1909,1165,1394,2161,2996,1128,512,2499,2316,3028,1468,350,1952,2283,2503,777,2696,2414,1522,2926,250,2568,1170,2135,106,1469,2745,1222,1668,1960,2843,1637,600,1523,232,1808,2701,52,2101,2814,1079,1203,1775,1879,375,1845,790,317,2288,2956,822,377,128,780,3045,2069,1670,2934,2172,2650,912,1370,2980,2173,2032,2385,1499,2918,1966,2725,2477,1083,2816,1920,2747,2230,2726,2882,2071,1673,505,1743,1528,428,570,261,877,1850,2074,494,737,659,2388,633,960,66,1105,624,2293,741,499,352,1132,430,694,1378,97,243,2600,529,2079,245,1086,348,178,2081,123,99,112,1184,1089,154,294,2265,573,113,1930,54,2044,239,574,211,360,901,1506,686,502,86,124,255,212,386,193,503,653,1349,326,2012,406,216,1243,813,297,14,415,533,169,798,688,63,240,1307,2402,173,366,1826,534,576,1420,241,1557
1.5576761325356283,0.7955852218137351,-0.1967746802526644,0.255952511861343,1.11545308586704,0.9180919307885846,0.6980630201166272,3.506338746109396,-0.030206765888258928,0.11498437510700303,-0.17986003989876528,1.8526640136185266,0.14666752913432865,0.30204211533490194,0.16243171108876198,-0.6027955681655673,0.2094183652836215,-0.1967746802526644,3.3206645838077886,-0.21374796024844483,1.6619426173233864,0.14666752913432865,1.9612496555436207,-0.3516910545716578,0.0348588523240148,-0.09615352598164383,-0.4756480043806108,-1.3773759425498497,0.06706796620069248,0.669827883440752,-0.6769429135129599,-0.5661333020712928,-1.6871559429488037,-0.1294642520833557,1.0243805753397968,-0.3692094267674327,-0.5479033919239744,-0.6769429135129599,0.3476949375688096,-0.8094210498506128,-0.6212288478544631,-0.16300366701431568,-1.1465595896590495,1.390659754720825,-0.7144356079504978,0.0348588523240148,-0.45774800066276633,2.341847947069304,-0.1294642520833557,-0.847927384389837,0.002434827265685641,-0.23078025553282336,-0.3692094267674327,-0.9652573139184435,-0.21374796024844483,0.5406573616707142,-0.16300366701431568,1.462976639584121,-0.2995072265011157,-0.8094210498506128,2.9237186077189423,-0.439912661259074,-0.9258411670371093,0.09906477879078189,0.018673868634717674,-0.28223504260053384,-0.3342348331799229,0.931509813270278,-0.3168403575565848,0.33252539041368356,1.1283203698531714,-0.5479033919239744,-1.2292802103878024,0.30204211533490194,0.931509813270278,2.056812333710736,0.3476949375688096,-2.1150366043388837,-0.42214155708180023,-0.23078025553282336,-1.1671130876239315,-0.4756480043806108,-0.7712094363609074,0.22497962854566572,-0.07958302654545266,-1.2922208324243658,-0.4756480043806108,-0.404434263179806,-0.6027955681655673,-0.14620519285903205,-1.1057021297619256,-0.3692094267674327,-0.828637115565359,-0.6583020446262418,0.09906477879078189,-0.9258411670371093,-0.3516910545716578,-0.847927384389837,-0.511643742111834,-0.828637115565359,-1.0450305627840744,-0.42214155708180023,-0.23078025553282336,0.6839663996681922,-0.26502341218255865,-0.16300366701431568,0.8093547404733235,0.5841039652256301,1.3418152746816723,0.255952511861343,-0.3168403575565848,-0.42214155708180023,0.7121179729480956,0.37789124027862775,0.4673573625937165,-0.6027955681655673,0.4968122165583206,0.19380682512269046,2.774061482172853,0.08309274884485632,0.5114719629049498,-0.5479033919239744,0.37789124027862775,0.6980630201166272,1.0243805753397968,0.06706796620069248,0.8093547404733235,0.4228328131433475,-0.07958302654545266,2.4200817299635164,1.414890812147365,-0.7332884144977851,0.6414242418555797,-0.42214155708180023,1.4027910875879954,0.09906477879078189,1.0374995229846102,1.7862524375899929,-0.42214155708180023,2.129773251435637,2.3811352391695215,2.2521766001450425,0.0348588523240148,0.09906477879078189,1.9072797273295248,1.2047904684516537,-0.529740355465412,0.5841039652256301,2.2521766001450425,-0.3516910545716578,2.906373043866094,-0.404434263179806,1.4389960408956042,0.5841039652256301,1.5693783522525775,0.9848028127589368,0.2404909124205327,-0.14620519285903205,0.43772031258177796,0.6980630201166272,2.5064930869004933,2.129773251435637,1.3784966610797764,1.5693783522525775,0.9180919307885846,1.6733834780213133,0.6980630201166272,0.4821074349746622,-0.06306863218986276,1.1025503963970487,-0.3867903586863053,0.8640358745112992,1.5576761325356283,0.002434827265685641,0.3173078764001649,1.1921319124623524,3.5664976928721157,0.836774272954116,0.6414242418555797,1.8306337022721588,0.33252539041368356,0.43772031258177796,2.78300653577057,1.4389960408956042,-0.030206765888258928,-0.6027955681655673,1.8195786448550066,0.9582316246880604,-0.2995072265011157,0.6414242418555797,0.5841039652256301,-0.09615352598164383,1.4389960408956042,-0.16300366701431568
3,069
Transporter
70
191
2.865823
0.004159
Q8N1F7,Q9UPT5,Q9Y619,O43760,Q03519,P41440,Q9Y6M7,Q15070,O96008,Q9HD45,Q99805,P05023,O15439,O14975,P08183,P52292,Q6NT16,Q9UJS0,Q96NB2,Q9H6H4,Q9Y584,Q96ES6,Q99523,Q93050,O95249,Q8NFH4,Q70HW3,Q13190,P12235,P00846,Q9P2W9,Q9Y487,Q9P253,Q00765,Q6NUK1,Q9UBX3,Q12907,P13473,Q8TAD4,Q9Y3B3,P12236,Q8N2H4,P24539,P35670,Q99567,P53985,Q9BQT8,Q9H2J7,O60645,Q8TB61,O95202,Q9Y6C9,Q9Y3A6,Q15043,Q8IXU6,Q15758,Q6N075,P49755,Q8NEW0,Q9UI14,Q86Y82,Q9HC21,P11279,O43772,P17900,P30825,P16615,P51572,Q9NZJ7,Q9H2V7
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
513,509,131,132,261,269,536,143,399,148,277,404,278,526,152,408,27,547,413,415,32,33,421,163,165,293,39,429,553,42,173,562,180,570,441,56,571,187,60,321,565,450,448,195,585,202,75,204,462,83,591,213,482,352,95,617,618,228,101,356,357,488,374,116,117,120,249,377,256,126
2468,2057,2942,700,1423,1424,1285,2373,526,608,278,132,116,950,462,1487,868,869,2278,1013,2471,1125,1520,2536,2617,591,165,1634,2314,1463,871,399,42,404,1098,1054,908,152,909,2063,1396,3051,374,553,565,187,249,117,683,1365,2743,448,1956,836,992,120,1637,195,928,2286,2678,269,1844,1058,790,228,377,929,408,1526,1262,2420,2873,1205,202,2476,1400,2140,1609,1338,724,1059,2874,840,669,725,1180,912,1703,1967,913,2512,570,1644,261,1207,1102,3037,971,1746,571,429,1103,1375,2818,1325,2146,352,143,2599,1788,617,2730,618,27,441,1926,39,844,915,357,95,1275,513,450,101,293,60,2111,83,1582,1446,3056,1536,1154,859,745,163,2240,765,33,3053,413,665,2303,1483,421,585,277,731,75,1978,654,666,712,732,204,126,415,769,488,148,1007,2308,256,1307,180,173,2585,1799,56,1939,356,1981,547,1010,1051,509,1458,815,482,321,562,32,752,1095,131,2895,2533,213,536
-0.6583020446262418,-0.42214155708180023,-1.2084727595847877,0.4078989792455411,-0.11278048268758513,-0.11278048268758513,-0.030206765888258928,-0.6027955681655673,0.6414242418555797,0.5260869274788118,1.2550845585859318,2.035749074885701,2.2218852461661323,0.19380682512269046,0.7540350803801485,-0.14620519285903205,0.255952511861343,0.255952511861343,-0.5479033919239744,0.14666752913432865,-0.6583020446262418,0.06706796620069248,-0.16300366701431568,-0.6956539386154175,-0.7522128562660492,0.5551835148202413,1.8526640136185266,-0.21374796024844483,-0.5661333020712928,-0.1294642520833557,0.255952511861343,0.8776079734066499,3.034827813634531,0.8640358745112992,0.08309274884485632,0.11498437510700303,0.22497962854566572,1.9072797273295248,0.22497962854566572,-0.42214155708180023,-0.09615352598164383,-2.421230489514741,0.931509813270278,0.6128502332132403,0.5841039652256301,1.7301647060416219,1.390659754720825,2.2218852461661323,0.43772031258177796,-0.07958302654545266,-0.847927384389837,0.781775583130449,-0.3692094267674327,0.2867278246330759,0.16243171108876198,2.1709437111682344,-0.21374796024844483,1.6619426173233864,0.2094183652836215,-0.5479033919239744,-0.79027866305354,1.304842448283804,-0.3168403575565848,0.11498437510700303,0.33252539041368356,1.4868337902652249,0.931509813270278,0.2094183652836215,0.8504247102515363,-0.16300366701431568,-0.013858605375158513,-0.6212288478544631,-1.0249681947485962,0.018673868634717674,1.6158927888366963,-0.6583020446262418,-0.09615352598164383,-0.45774800066276633,-0.1967746802526644,-0.06306863218986276,0.39291854449948976,0.11498437510700303,-1.0249681947485962,0.2867278246330759,0.45256174173642805,0.39291854449948976,0.0348588523240148,0.22497962854566572,-0.24787194526949927,-0.3692094267674327,0.22497962854566572,-0.6769429135129599,0.5841039652256301,-0.21374796024844483,1.3418152746816723,0.018673868634717674,0.08309274884485632,-1.802496194966027,0.17814470796339205,-0.26502341218255865,0.5841039652256301,0.8093547404733235,0.08309274884485632,-0.07958302654545266,-0.9258411670371093,-0.04660999391817365,-0.45774800066276633,1.0243805753397968,1.9719673804988322,-0.7332884144977851,-0.28223504260053384,0.5260869274788118,-0.828637115565359,0.5260869274788118,3.3285620139858545,0.7955852218137351,-0.3516910545716578,3.0768243981140175,0.2867278246330759,0.22497962854566572,0.9980324104770499,2.439428869539286,-0.013858605375158513,0.669827883440752,0.781775583130449,2.3615345361909066,1.2047904684516537,2.818607017092348,-0.439912661259074,2.525471026963564,-0.17986003989876528,-0.11278048268758513,-2.8880273370908376,-0.16300366701431568,0.05099010895251097,0.2713647192914942,0.37789124027862775,1.863639502869007,-0.511643742111834,0.36281679569392605,3.2328322525717677,-2.4475743372505123,0.836774272954116,0.4673573625937165,-0.5479033919239744,-0.1294642520833557,0.8230843533330983,0.5696656342376731,1.2675738869198223,0.39291854449948976,2.6836037582923837,-0.3692094267674327,0.4821074349746622,0.4673573625937165,0.4078989792455411,0.39291854449948976,1.6043080729323946,2.1090467965731245,0.836774272954116,0.36281679569392605,0.7261314845184232,1.950506657749701,0.16243171108876198,-0.5479033919239744,1.3784966610797764,-0.030206765888258928,1.7862524375899929,1.8195786448550066,-0.7144356079504978,-0.28223504260053384,2.8451205119843253,-0.3516910545716578,1.011224934348964,-0.3692094267674327,0.6271586509706826,0.16243171108876198,0.13085185405757133,0.6839663996681922,-0.11278048268758513,0.3173078764001649,0.740103779395975,1.1283203698531714,0.5984987511004508,3.248934240656014,0.37789124027862775,0.09906477879078189,2.0462929128969036,-1.065173276993352,-0.6769429135129599,1.5693783522525775,0.6414242418555797
3,069
Receptor
17
39
2.853531
0.004324
Q99523,O15031,Q9NS69,Q14108,P11279,Q99720,Q99623,O15173,P30825,Q8WTV0,Q07954,P02786,Q9Y5M8,O00264,Q15375,O15118,P55899
Functions
Protein Atlas Molecular function
protein_atlas_molecular_function
421,382,4,37,374,107,333,109,120,16,371,181,183,214,338,91,157
214,382,91,109,181,1194,1128,872,2192,2194,2256,417,374,722,966,1604,120,789,157,371,854,37,634,614,338,617,842,16,3063,2363,421,333,107,4,496,2667,1830,183,2564
1.5576761325356283,0.9180919307885846,2.449071204722446,2.3220747758671,1.7750896222834918,0.018673868634717674,0.06706796620069248,0.255952511861343,-0.4936131056899879,-0.4936131056899879,-0.529740355465412,0.8230843533330983,0.931509813270278,0.39291854449948976,0.17814470796339205,-0.1967746802526644,2.1709437111682344,0.33252539041368356,1.8855117311614753,0.9448896451261036,0.2713647192914942,3.176002075643978,0.4968122165583206,0.5260869274788118,1.0505819654024655,0.5260869274788118,0.2867278246330759,3.544036436727491,-4.51731391823549,-0.5844305409591135,0.8230843533330983,1.0636280893102765,2.341847947069304,4.125669255470878,0.7121179729480956,-0.7712094363609074,-0.2995072265011157,1.752682141866282,-0.6956539386154175
3,069
Intracellular protein transmembrane transport
10
21
2.841999
0.004483
O60830,Q99595,Q3ZCQ8,O75381,O96008,Q9UGP8,Q99442,O14925,Q15629,Q8N4Q1
Processes and pathways
GO Biological process
msigdb_gobp
0,3,541,361,399,534,503,146,51,412
146,1096,0,965,361,757,564,399,2162,1467,2069,1919,912,51,541,412,503,3,1136,534,948
1.950506657749701,0.08309274884485632,4.125669255470878,0.17814470796339205,0.97153594878527,0.36281679569392605,0.5841039652256301,0.8776079734066499,-0.4756480043806108,-0.1294642520833557,-0.42214155708180023,-0.3516910545716578,0.22497962854566572,2.9409961260648005,0.6271586509706826,0.836774272954116,0.6980630201166272,4.125669255470878,0.06706796620069248,0.6414242418555797,0.2094183652836215
3,069
Liposaccharide metabolic process
6
16
2.838328
0.004535
Q8NBX0,P06280,P16278,P04062,Q99805,P17900
Processes and pathways
GO Biological process
msigdb_gobp
197,295,203,45,277,117
1053,1255,45,658,295,328,775,203,117,877,808,197,1538,1412,277,768
0.11498437510700303,-0.013858605375158513,3.017915919263261,0.4673573625937165,1.1921319124623524,1.0766380800365236,0.3476949375688096,1.6043080729323946,2.2218852461661323,0.255952511861343,0.3173078764001649,1.650473249640468,-0.16300366701431568,-0.09615352598164383,1.2675738869198223,0.36281679569392605
3,069
Sphingolipid metabolism
6
10
2.830323
0.00465
Q06136,Q13510,P04062,P07602,P17900,Q9NZ01
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
167,139,45,48,117,63
383,1601,194,45,48,117,167,139,808,63
0.9180919307885846,-0.1967746802526644,1.6619426173233864,3.017915919263261,2.9924252844164885,2.2218852461661323,1.8526640136185266,1.9933274484979564,0.3173078764001649,2.78300653577057
3,069
Respiratory failure
19
62
2.823282
0.004753
Q9Y619,Q13510,Q9BT22,P35637,Q15165,Q16637,P23786,Q70HW3,P07602,O75306,Q9UMS0,Q92804,Q8TD16,Q9BUB7,P10253,P53701,Q5XKP0,P50995,Q9NZJ7
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
131,139,406,280,153,419,166,39,48,437,460,200,208,469,85,103,244,376,256
563,1986,437,1770,1634,1465,48,2023,954,85,2677,3016,1955,2984,1667,166,1915,280,1319,2258,1202,1174,2325,376,1226,103,1263,2451,1786,139,634,1502,153,419,1232,1647,1153,244,39,2602,501,1820,996,2733,208,900,200,1796,918,785,2047,406,1542,833,469,980,1586,1867,256,460,1486,131
0.5841039652256301,-0.3867903586863053,0.7955852218137351,-0.28223504260053384,-0.21374796024844483,-0.1294642520833557,2.9924252844164885,-0.404434263179806,0.19380682512269046,2.5064930869004933,-0.79027866305354,-1.5299171060170624,-0.3692094267674327,-1.313376008354104,-0.23078025553282336,1.8526640136185266,-0.3516910545716578,1.2550845585859318,-0.04660999391817365,-0.529740355465412,0.018673868634717674,0.0348588523240148,-0.5661333020712928,0.931509813270278,0.002434827265685641,2.351702020702256,-0.013858605375158513,-0.6397308488356486,-0.28223504260053384,1.9933274484979564,0.4968122165583206,-0.14620519285903205,1.9072797273295248,0.8230843533330983,0.002434827265685641,-0.21374796024844483,0.05099010895251097,1.4027910875879954,3.0768243981140175,-0.7332884144977851,0.6980630201166272,-0.2995072265011157,0.16243171108876198,-0.828637115565359,1.5926941854384824,0.2404909124205327,1.638975243829338,-0.28223504260053384,0.22497962854566572,0.3476949375688096,-0.404434263179806,0.8640358745112992,-0.16300366701431568,0.30204211533490194,0.7540350803801485,0.17814470796339205,-0.17986003989876528,-0.3168403575565848,1.3784966610797764,0.7679256085196353,-0.1294642520833557,2.0462929128969036
3,069
Mitochondrial envelope
115
315
2.820771
0.004791
O60830,Q99595,Q9NS69,P14406,Q96AQ8,P45880,Q7Z7H8,Q9Y2R0,Q6UXV4,P21796,O43169,Q9H4I9,Q8N4H5,Q9UJS0,Q9GZY8,Q9Y584,Q3ZCQ8,P62072,P13073,O43676,Q9H061,Q70HW3,P00846,Q69YU5,Q96B49,P12235,Q9UDX5,P30536,Q9UBX3,Q9UDW1,P12236,O95831,O43819,Q9H2W6,Q9UG56,O14949,Q9BQT8,Q96ER9,O95168,O95202,P09601,O75964,P53701,Q13505,P00403,Q567V2,Q96A26,O43772,Q9BRJ2,Q9H2V7,Q9Y619,Q9Y277,Q6DKK2,Q15070,O14925,P21912,Q9Y6M9,P23786,Q9H845,Q9NR28,Q9NUQ2,Q10713,Q86Y39,P52789,O15121,P57105,Q8WWC4,Q9Y6C9,O00264,Q5HYI7,O96000,Q96CU9,P03915,Q5XKP0,Q9NZJ7,Q9Y5J9,Q9P0J0,Q9UKU0,Q6P4A7,O00584,Q7Z7F7,P39210,O00165,Q9BUK6,Q8IWA4,Q7KZN9,P54886,Q99623,Q9BPX6,Q86WA6,O60220,Q96BR5,Q9NVI7,Q9Y512,Q8IYU8,Q8N8Q8,Q9H3K2,O96008,Q5T9A4,Q8N4Q1,Q96NB2,Q9NX63,Q8NBN7,Q6NUK1,O75306,P24539,Q9Y320,O75880,Q9BUB7,Q9Y291,Q96AY3,Q9HC21,O75600,Q12981,Q8N183
Localization
GO Cellular component
msigdb_gocc
0,3,4,1,514,8,10,11,519,15,19,24,25,547,544,32,541,35,538,38,40,39,42,43,44,553,49,53,56,57,565,564,563,586,69,70,75,594,590,591,88,93,103,104,108,110,114,116,125,126,131,138,140,143,146,158,161,166,168,170,176,177,179,188,205,209,210,213,214,223,225,230,242,244,256,258,271,282,290,289,291,300,314,324,327,331,330,333,343,341,335,355,364,367,384,389,397,399,410,412,413,445,444,441,437,448,461,463,469,481,478,488,491,494,501
314,679,214,1422,1218,289,3067,146,70,205,818,2498,19,2861,1096,1945,38,1288,116,563,335,802,2277,0,1013,1836,437,2312,681,1428,1429,491,1731,1125,463,1520,93,1837,757,835,590,591,1947,1463,1948,1014,564,225,399,1909,108,42,242,1910,1054,908,2446,1055,910,2644,1490,88,1951,2447,1167,2162,682,553,565,2472,538,1,1198,2098,2793,2131,777,1258,2132,778,15,158,2794,668,911,1170,166,448,1956,2899,2137,53,1606,1315,692,1841,1077,1318,928,759,2415,300,1319,1294,892,8,969,2865,2998,874,2797,1295,970,1641,1434,188,1177,1100,1262,103,1964,330,2451,1059,840,209,35,1997,1298,2072,1527,1782,1783,2764,931,913,3008,2290,1644,2987,177,1705,494,2144,1885,1208,104,972,1105,143,1970,2579,934,1924,881,2519,661,541,827,110,223,2456,2966,410,1153,994,244,43,140,1301,441,2521,290,1110,519,1577,39,331,2946,1234,291,10,341,179,327,743,1111,2991,384,501,995,25,412,1184,1579,389,1793,444,996,2960,1580,1682,604,2487,210,1447,1411,1583,830,1448,114,961,514,478,44,355,2010,230,2082,1001,594,785,1158,674,413,1798,652,2782,811,3,333,343,766,75,125,861,833,469,324,3062,1092,2858,2049,1544,2584,1621,2117,2245,544,40,980,126,586,397,24,168,2305,769,1215,770,1136,488,1137,1159,904,963,2120,677,170,1007,1139,4,176,985,1030,364,1008,905,445,788,256,1248,1870,271,56,57,49,69,799,547,1309,282,716,964,138,481,1630,11,1251,1459,461,1120,717,1762,1691,947,772,1462,865,367,32,258,131,213,161
1.1283203698531714,0.43772031258177796,1.5576761325356283,-0.11278048268758513,0.002434827265685641,1.2300052027613868,-8.86661206184794,1.950506657749701,2.7380995161851818,1.5926941854384824,0.30204211533490194,-0.6769429135129599,3.506338746109396,-1.0049855843887756,0.08309274884485632,-0.3692094267674327,3.143192229979514,-0.030206765888258928,2.2218852461661323,0.5841039652256301,1.0505819654024655,0.3173078764001649,-0.5479033919239744,4.125669255470878,0.14666752913432865,-0.3168403575565848,0.7955852218137351,-0.5661333020712928,0.43772031258177796,-0.11278048268758513,-0.11278048268758513,0.7121179729480956,-0.26502341218255865,0.06706796620069248,0.7540350803801485,-0.16300366701431568,2.449071204722446,-0.3168403575565848,0.36281679569392605,0.2867278246330759,0.5551835148202413,0.5551835148202413,-0.3692094267674327,-0.1294642520833557,-0.3692094267674327,0.14666752913432865,0.5841039652256301,1.4987164375383368,0.8776079734066499,-0.3516910545716578,2.3319722280450734,3.034827813634531,1.4269590798007796,-0.3516910545716578,0.11498437510700303,0.22497962854566572,-0.6397308488356486,0.11498437510700303,0.22497962854566572,-0.7712094363609074,-0.14620519285903205,2.4874342296963574,-0.3692094267674327,-0.6397308488356486,0.0348588523240148,-0.4756480043806108,0.43772031258177796,0.6128502332132403,0.5841039652256301,-0.6583020446262418,0.6271586509706826,4.125669255470878,0.018673868634717674,-0.439912661259074,-0.9062487336772611,-0.45774800066276633,0.3476949375688096,-0.013858605375158513,-0.45774800066276633,0.3476949375688096,3.551536551149184,1.8745887034572348,-0.9062487336772611,0.45256174173642805,0.22497962854566572,0.0348588523240148,1.8526640136185266,0.781775583130449,-0.3692094267674327,-1.0853969322237222,-0.45774800066276633,2.915054362320261,-0.1967746802526644,-0.04660999391817365,0.4228328131433475,-0.3168403575565848,0.09906477879078189,-0.04660999391817365,0.2094183652836215,0.36281679569392605,-0.6212288478544631,1.1794390031101867,-0.04660999391817365,-0.030206765888258928,0.2404909124205327,3.7990432016623545,0.17814470796339205,-1.0049855843887756,-1.3773759425498497,0.255952511861343,-0.9062487336772611,-0.030206765888258928,0.17814470796339205,-0.21374796024844483,-0.11278048268758513,1.7301647060416219,0.0348588523240148,0.08309274884485632,-0.013858605375158513,2.351702020702256,-0.3692094267674327,1.0766380800365236,-0.6397308488356486,0.11498437510700303,0.2867278246330759,1.5810509907278525,3.2085671141055583,-0.3867903586863053,-0.030206765888258928,-0.42214155708180023,-0.16300366701431568,-0.28223504260053384,-0.28223504260053384,-0.8672923859684633,0.2094183652836215,0.22497962854566572,-1.4421921442388042,-0.5479033919239744,-0.21374796024844483,-1.313376008354104,1.7862524375899929,-0.24787194526949927,0.7121179729480956,-0.45774800066276633,-0.3342348331799229,0.018673868634717674,2.351702020702256,0.17814470796339205,0.08309274884485632,1.9719673804988322,-0.3692094267674327,-0.7144356079504978,0.2094183652836215,-0.3516910545716578,0.255952511861343,-0.6769429135129599,0.4673573625937165,0.6271586509706826,0.30204211533490194,2.2722584093916285,1.5105686587244185,-0.6397308488356486,-1.250173600739404,0.8504247102515363,0.05099010895251097,0.16243171108876198,1.4027910875879954,3.034827813634531,1.9933274484979564,-0.030206765888258928,0.7955852218137351,-0.6769429135129599,1.2300052027613868,0.08309274884485632,0.655647241447091,-0.17986003989876528,3.0768243981140175,1.0766380800365236,-1.2084727595847877,0.002434827265685641,1.2174148419920963,3.677076391361871,1.0505819654024655,1.7862524375899929,1.0896121215347725,0.37789124027862775,0.08309274884485632,-1.3346197932429562,0.9180919307885846,0.6980630201166272,0.16243171108876198,3.445328693074278,0.836774272954116,0.0348588523240148,-0.17986003989876528,0.9046357978310428,-0.28223504260053384,0.7955852218137351,0.16243171108876198,-1.2292802103878024,-0.17986003989876528,-0.23078025553282336,0.5406573616707142,-0.6583020446262418,1.5693783522525775,-0.11278048268758513,-0.09615352598164383,-0.17986003989876528,0.30204211533490194,-0.11278048268758513,2.2421020600878725,0.19380682512269046,0.669827883440752,0.740103779395975,3.026380013898526,1.011224934348964,-0.3867903586863053,1.474920572686217,-0.42214155708180023,0.16243171108876198,0.5551835148202413,0.3476949375688096,0.05099010895251097,0.45256174173642805,0.836774272954116,-0.28223504260053384,0.4821074349746622,-0.8867326554727312,0.3173078764001649,4.125669255470878,1.0636280893102765,1.0505819654024655,0.36281679569392605,2.6836037582923837,2.129773251435637,0.2713647192914942,0.30204211533490194,0.7540350803801485,1.11545308586704,-4.143073348298599,0.09906477879078189,-0.9850821494668925,-0.404434263179806,-0.16300366701431568,-0.7144356079504978,-0.1967746802526644,-0.439912661259074,-0.511643742111834,0.6271586509706826,3.0768243981140175,0.17814470796339205,2.1090467965731245,0.5696656342376731,0.8911412130144085,3.475941491201594,1.8526640136185266,-0.5479033919239744,0.36281679569392605,0.018673868634717674,0.36281679569392605,0.06706796620069248,0.7261314845184232,0.06706796620069248,0.05099010895251097,0.2404909124205327,0.19380682512269046,-0.439912661259074,0.45256174173642805,1.8306337022721588,0.16243171108876198,0.06706796620069248,4.125669255470878,1.8084968281201592,0.17814470796339205,0.14666752913432865,0.97153594878527,0.16243171108876198,0.2404909124205327,0.7955852218137351,0.3476949375688096,1.3784966610797764,0.002434827265685641,-0.3168403575565848,1.2924526686835236,2.8451205119843253,2.8451205119843253,2.9838954271236515,2.7561169853489744,0.33252539041368356,0.6271586509706826,-0.030206765888258928,1.2550845585859318,0.4078989792455411,0.19380682512269046,2.0145877281129803,0.740103779395975,-0.1967746802526644,3.677076391361871,0.002434827265685641,-0.11278048268758513,0.7679256085196353,0.08309274884485632,0.4078989792455411,-0.26502341218255865,-0.23078025553282336,0.2094183652836215,0.36281679569392605,-0.11278048268758513,0.2713647192914942,0.9582316246880604,3.248934240656014,1.366301653124708,2.0462929128969036,1.5693783522525775,1.8745887034572348
3,069
Muscle abnormality related to mitochondrial dysfunction
10
35
2.818163
0.00483
Q9Y6M9,O96000,O43676,Q96CU9,P00846,Q9Y2R0,P00403,P03915,Q86Y39,Q9UBX3
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
161,225,38,230,42,11,108,242,179,56
679,1218,38,802,1836,437,2312,1429,225,108,42,242,553,2132,2899,2258,2797,1081,1226,827,179,501,1929,2487,230,833,324,904,1870,56,11,1943,717,1556,161
0.43772031258177796,0.002434827265685641,3.143192229979514,0.3173078764001649,-0.3168403575565848,0.7955852218137351,-0.5661333020712928,-0.11278048268758513,1.4987164375383368,2.3319722280450734,3.034827813634531,1.4269590798007796,0.6128502332132403,-0.45774800066276633,-1.0853969322237222,-0.529740355465412,-0.9062487336772611,0.09906477879078189,0.002434827265685641,0.30204211533490194,1.7862524375899929,0.6980630201166272,-0.3516910545716578,-0.6583020446262418,1.474920572686217,0.30204211533490194,1.11545308586704,0.2404909124205327,-0.3168403575565848,2.8451205119843253,3.677076391361871,-0.3516910545716578,0.4078989792455411,-0.16300366701431568,1.8745887034572348
3,069
Visual loss
14
50
2.810977
0.004939
O14773,P53701,P00846,P00403,P50897,P07602,Q10713,O75306,P03915,O60220,O15460,P48449,O75503,Q9NZJ7
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
67,103,42,108,13,48,177,437,242,335,497,407,58,256
1664,1764,1163,1422,67,497,335,802,437,1428,58,1946,835,108,2825,42,1127,242,1838,703,48,2855,2939,1955,1912,2134,758,1916,1807,1319,407,13,1261,1568,504,103,1745,177,1614,2328,1374,782,2683,1581,900,1064,1091,2851,606,256
-0.23078025553282336,-0.28223504260053384,0.0348588523240148,-0.11278048268758513,2.7650983212483924,0.6980630201166272,1.0505819654024655,0.3173078764001649,0.7955852218137351,-0.11278048268758513,2.8363003459677576,-0.3692094267674327,0.2867278246330759,2.3319722280450734,-0.9455105077664233,3.034827813634531,0.06706796620069248,1.4269590798007796,-0.3168403575565848,0.4078989792455411,2.9924252844164885,-0.9850821494668925,-1.1877505993006687,-0.3692094267674327,-0.3516910545716578,-0.45774800066276633,0.36281679569392605,-0.3516910545716578,-0.2995072265011157,-0.04660999391817365,0.8504247102515363,3.6110714012320395,-0.013858605375158513,-0.17986003989876528,0.6839663996681922,2.351702020702256,-0.26502341218255865,1.7862524375899929,-0.1967746802526644,-0.5661333020712928,-0.07958302654545266,0.3476949375688096,-0.79027866305354,-0.17986003989876528,0.2404909124205327,0.11498437510700303,0.09906477879078189,-0.9652573139184435,0.5406573616707142,1.3784966610797764
3,069
Proton transmembrane transport
13
43
2.8053
0.005027
Q96ES6,P24539,P13073,Q7KZN9,P00846,P51790,P00403,Q99623,P03915,P05023,Q9UDW1,Q8TAD4,O75964
Processes and pathways
GO Biological process
msigdb_gobp
33,448,538,331,42,329,108,333,242,404,57,60,93
700,1218,1035,1836,1520,93,108,42,242,404,1054,908,910,1167,553,538,778,1365,2743,448,1956,2137,1315,928,1078,2678,969,2865,329,1059,840,1180,913,1208,331,60,33,2782,333,57,1594,1939,1309
0.4078989792455411,0.002434827265685641,0.13085185405757133,-0.3168403575565848,-0.16300366701431568,2.449071204722446,2.3319722280450734,3.034827813634531,1.4269590798007796,0.8640358745112992,0.11498437510700303,0.22497962854566572,0.22497962854566572,0.0348588523240148,0.6128502332132403,0.6271586509706826,0.3476949375688096,-0.07958302654545266,-0.847927384389837,0.781775583130449,-0.3692094267674327,-0.45774800066276633,-0.04660999391817365,0.2094183652836215,0.09906477879078189,-0.79027866305354,0.17814470796339205,-1.0049855843887756,1.0766380800365236,0.11498437510700303,0.2867278246330759,0.0348588523240148,0.22497962854566572,0.018673868634717674,1.0766380800365236,2.818607017092348,3.2328322525717677,-0.8867326554727312,1.0636280893102765,2.8451205119843253,-0.17986003989876528,-0.3516910545716578,-0.030206765888258928
3,069
Establishment of protein localization to membrane
29
89
2.804524
0.005039
O14737,Q9NS69,Q9Y5J9,Q9NPA0,Q8N8Q8,Q15904,Q15070,Q9P0J0,Q9UGP8,P56589,Q9NT62,Q9GZY8,Q9Y584,P62072,O43681,Q15629,P43307,P46379,Q9HD20,Q8N2H4,P40855,Q8WWC4,Q96A33,O60220,O15118,O60725,Q9Y512,Q99442,Q15041
Processes and pathways
GO Biological process
msigdb_gobp
381,4,258,524,389,266,143,271,534,273,546,544,32,35,298,51,52,185,61,450,316,210,211,335,91,92,367,503,499
2186,2942,381,867,91,1560,298,925,335,92,1519,2888,757,1948,1098,2315,2192,2447,2134,609,2762,2285,2795,2746,316,1774,52,185,2139,893,1368,1739,2031,273,2069,1882,1919,556,912,35,2651,1745,2423,1103,1814,2202,648,499,2765,143,51,266,625,827,1268,1479,450,1276,389,996,1304,210,211,918,2303,503,2181,544,621,1623,1546,61,1282,524,677,4,546,271,534,1827,1594,987,2870,1800,964,367,32,258,948
-0.4936131056899879,-1.2084727595847877,0.9180919307885846,0.255952511861343,2.449071204722446,-0.17986003989876528,1.1794390031101867,0.2094183652836215,1.0505819654024655,2.449071204722446,-0.16300366701431568,-1.065173276993352,0.36281679569392605,-0.3692094267674327,0.08309274884485632,-0.5661333020712928,-0.4936131056899879,-0.6397308488356486,-0.45774800066276633,0.5260869274788118,-0.8672923859684633,-0.5479033919239744,-0.9062487336772611,-0.847927384389837,1.1283203698531714,-0.28223504260053384,2.9237186077189423,1.7414372304609023,-0.45774800066276633,0.2404909124205327,-0.07958302654545266,-0.26502341218255865,-0.404434263179806,1.280029869062608,-0.42214155708180023,-0.3342348331799229,-0.3516910545716578,0.6128502332132403,0.22497962854566572,3.2085671141055583,-0.7712094363609074,-0.26502341218255865,-0.6212288478544631,0.08309274884485632,-0.2995072265011157,-0.4936131056899879,0.4821074349746622,0.6980630201166272,-0.8672923859684633,1.9719673804988322,2.9409961260648005,1.317199369207603,0.5114719629049498,0.30204211533490194,-0.013858605375158513,-0.1294642520833557,0.781775583130449,-0.013858605375158513,0.9046357978310428,0.16243171108876198,-0.030206765888258928,1.5693783522525775,1.5693783522525775,0.22497962854566572,-0.5479033919239744,0.6980630201166272,-0.4756480043806108,0.6271586509706826,0.5260869274788118,-0.1967746802526644,-0.16300366701431568,2.8008425897497315,-0.013858605375158513,0.655647241447091,0.45256174173642805,4.125669255470878,0.6271586509706826,1.2924526686835236,0.6414242418555797,-0.2995072265011157,-0.17986003989876528,0.17814470796339205,-1.0049855843887756,-0.28223504260053384,0.19380682512269046,0.9582316246880604,3.248934240656014,1.366301653124708,0.2094183652836215
3,069
Transporter complex
20
61
2.80402
0.005047
Q9Y5J9,Q8N2K0,P62942,Q9P0J0,P05023,Q9H4I9,Q9C0H2,Q9Y6M9,P62072,O43676,Q86Y39,Q9UDW1,O14949,Q9BPX6,O60220,O96000,Q96CU9,O75381,P03915,Q8IYU8
Localization
GO Cellular component
msigdb_gocc
258,393,392,271,404,24,26,161,35,38,179,57,70,343,335,225,230,361,242,384
679,1944,1218,70,1945,38,1288,335,1836,437,2312,361,1429,590,1947,225,242,404,1098,910,2447,1198,2793,2742,2132,668,2899,1315,969,2797,1568,1434,2140,35,392,1405,1788,881,2519,626,179,898,384,393,1580,522,1753,230,594,343,3062,26,24,698,271,57,964,717,258,1389,161
0.43772031258177796,-0.3692094267674327,0.002434827265685641,2.7380995161851818,-0.3692094267674327,3.143192229979514,-0.030206765888258928,1.0505819654024655,-0.3168403575565848,0.7955852218137351,-0.5661333020712928,0.97153594878527,-0.11278048268758513,0.5551835148202413,-0.3692094267674327,1.4987164375383368,1.4269590798007796,0.8640358745112992,0.08309274884485632,0.22497962854566572,-0.6397308488356486,0.018673868634717674,-0.9062487336772611,-0.847927384389837,-0.45774800066276633,0.45256174173642805,-1.0853969322237222,-0.04660999391817365,0.17814470796339205,-0.9062487336772611,-0.17986003989876528,-0.11278048268758513,-0.45774800066276633,3.2085671141055583,0.8911412130144085,-0.09615352598164383,-0.28223504260053384,0.255952511861343,-0.6769429135129599,0.5114719629049498,1.7862524375899929,0.2404909124205327,0.9180919307885846,0.8911412130144085,-0.17986003989876528,0.655647241447091,-0.26502341218255865,1.474920572686217,0.5551835148202413,1.0505819654024655,-4.143073348298599,3.344313892455025,3.475941491201594,0.4228328131433475,1.2924526686835236,2.8451205119843253,0.19380682512269046,0.4078989792455411,1.366301653124708,-0.07958302654545266,1.8745887034572348
3,069
Nadh dehydrogenase complex assembly
9
28
2.800175
0.005107
Q9Y6M9,O96000,O43676,Q9H061,Q9H845,Q96CU9,Q15070,P03915,Q86Y39
Processes and pathways
GO Biological process
msigdb_gobp
161,225,38,40,168,230,143,242,179
679,1945,38,1288,1836,437,1429,590,1947,225,242,2899,1434,143,881,2519,179,501,1929,230,833,40,168,1870,271,964,717,161
0.43772031258177796,-0.3692094267674327,3.143192229979514,-0.030206765888258928,-0.3168403575565848,0.7955852218137351,-0.11278048268758513,0.5551835148202413,-0.3692094267674327,1.4987164375383368,1.4269590798007796,-1.0853969322237222,-0.11278048268758513,1.9719673804988322,0.255952511861343,-0.6769429135129599,1.7862524375899929,0.6980630201166272,-0.3516910545716578,1.474920572686217,0.30204211533490194,3.0768243981140175,1.8526640136185266,-0.3168403575565848,1.2924526686835236,0.19380682512269046,0.4078989792455411,1.8745887034572348
3,069
Golgi membrane
38
123
2.798368
0.005136
Q92896,Q7LGA3,Q9Y282,Q8NF37,P52292,O95197,O00461,Q7Z3C6,Q14108,Q9NTJ5,P61026,O95249,Q13190,Q9P2W9,O15258,O43505,Q10713,Q9H7Z7,Q9UM00,Q8IZA0,Q9Y3B3,Q8N2H4,O15260,P10321,P35670,O75396,P51790,Q6RW13,Q8TB61,Q10472,Q86SF2,Q15392,Q8IV08,P49755,Q86Y82,O95070,P51572,Q8TBA6
Localization
GO Cellular component
msigdb_gocc
257,259,17,154,408,28,29,284,37,557,556,165,429,173,558,559,177,305,576,443,321,450,322,323,195,447,329,340,83,337,476,96,99,228,357,248,377,507
753,700,29,1285,2373,867,558,322,801,559,2695,2278,447,1987,248,28,165,1562,871,1127,703,1911,3028,323,3051,722,1145,1637,789,195,1807,821,1294,1844,1058,790,228,1433,763,377,329,408,1225,2420,2873,2874,2829,791,1228,1882,684,556,1038,1703,1264,1083,2875,3039,1207,1676,337,1102,177,571,429,1813,37,615,2800,1788,96,1267,2262,340,1087,259,284,2687,476,357,99,443,450,1088,1112,710,154,83,507,1714,1536,1381,257,831,918,654,2048,1028,813,631,305,1546,3036,1282,2308,557,986,1307,173,2585,1594,2438,1760,576,17,815,2159,1070,2738,1120,321,2056,2533
0.36281679569392605,0.4078989792455411,3.2729760807044963,-0.030206765888258928,-0.6027955681655673,0.255952511861343,0.5984987511004508,1.11545308586704,0.3173078764001649,0.5984987511004508,-0.8094210498506128,-0.5479033919239744,0.781775583130449,-0.3867903586863053,1.390659754720825,3.3206645838077886,1.8526640136185266,-0.17986003989876528,0.255952511861343,0.06706796620069248,0.4078989792455411,-0.3516910545716578,-1.6871559429488037,1.11545308586704,-2.421230489514741,0.39291854449948976,0.05099010895251097,-0.21374796024844483,0.33252539041368356,1.6619426173233864,-0.2995072265011157,0.30204211533490194,-0.030206765888258928,-0.3168403575565848,0.11498437510700303,0.33252539041368356,1.4868337902652249,-0.11278048268758513,0.36281679569392605,0.931509813270278,1.0766380800365236,0.8504247102515363,0.002434827265685641,-0.6212288478544631,-1.0249681947485962,-1.0249681947485962,-0.9455105077664233,0.33252539041368356,0.002434827265685641,-0.3342348331799229,0.43772031258177796,0.6128502332132403,0.13085185405757133,-0.24787194526949927,-0.013858605375158513,0.09906477879078189,-1.0249681947485962,-1.8258778596959944,0.018673868634717674,-0.23078025553282336,1.0505819654024655,0.08309274884485632,1.7862524375899929,0.5841039652256301,0.8093547404733235,-0.2995072265011157,3.176002075643978,0.5260869274788118,-0.9062487336772611,-0.28223504260053384,2.4297657388802323,-0.013858605375158513,-0.529740355465412,1.0505819654024655,0.09906477879078189,1.3540745762314421,1.242561719212632,-0.79027866305354,0.740103779395975,0.9980324104770499,2.3811352391695215,0.7955852218137351,0.781775583130449,0.09906477879078189,0.08309274884485632,0.4078989792455411,1.9072797273295248,2.525471026963564,0.6839663996681922,-0.24787194526949927,-0.16300366701431568,-0.07958302654545266,1.366301653124708,0.30204211533490194,0.22497962854566572,0.4821074349746622,-0.404434263179806,0.14666752913432865,0.3173078764001649,0.5114719629049498,1.1539494344082741,-0.16300366701431568,-1.756049079272557,-0.013858605375158513,-0.5479033919239744,0.6128502332132403,0.17814470796339205,-0.030206765888258928,1.8195786448550066,-0.7144356079504978,-0.17986003989876528,-0.6212288478544631,-0.26502341218255865,0.5841039652256301,3.544036436727491,0.3173078764001649,-0.45774800066276633,0.11498437510700303,-0.828637115565359,0.08309274884485632,1.1283203698531714,-0.404434263179806,-0.6769429135129599
3,069
Myoclonus
16
90
2.796386
0.005168
P00374,O14773,Q14108,Q96CU9,P00846,P27544,P00403,P04062,P50897,Q13510,P07602,Q01105,Q10713,P03915,Q9UBX3,O75503
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
64,67,37,230,42,106,108,45,13,139,48,81,177,242,56,58
1218,2853,1122,67,774,2534,58,1769,1362,1393,399,64,108,42,242,45,1949,48,2096,315,3051,538,2319,1365,1397,106,758,1914,1606,1200,2351,2286,2678,1336,2449,2797,1567,13,2383,1147,1226,2141,1322,823,824,2512,81,957,2945,2905,1183,177,1614,2328,139,1500,37,1968,2482,2456,672,1270,742,2005,995,996,1682,1064,486,230,2431,785,502,1895,2335,2605,2490,1091,833,2399,980,606,904,1626,256,56,1283,1421,865,2822
0.002434827265685641,-0.9850821494668925,0.06706796620069248,2.7650983212483924,0.3476949375688096,-0.6956539386154175,2.8363003459677576,-0.28223504260053384,-0.07958302654545266,-0.09615352598164383,0.8776079734066499,2.774061482172853,2.3319722280450734,3.034827813634531,1.4269590798007796,3.017915919263261,-0.3692094267674327,2.9924252844164885,-0.439912661259074,1.1283203698531714,-2.421230489514741,0.6271586509706826,-0.5661333020712928,-0.07958302654545266,-0.09615352598164383,2.341847947069304,0.36281679569392605,-0.3516910545716578,-0.1967746802526644,0.018673868634717674,-0.5844305409591135,-0.5479033919239744,-0.79027866305354,-0.06306863218986276,-0.6397308488356486,-0.9062487336772611,-0.17986003989876528,3.6110714012320395,-0.6027955681655673,0.05099010895251097,0.002434827265685641,-0.45774800066276633,-0.04660999391817365,0.30204211533490194,0.30204211533490194,-0.6769429135129599,2.563186671331025,0.19380682512269046,-1.2084727595847877,-1.0853969322237222,0.0348588523240148,1.7862524375899929,-0.1967746802526644,-0.5661333020712928,1.9933274484979564,-0.14620519285903205,3.176002075643978,-0.3692094267674327,-0.6583020446262418,-0.6397308488356486,0.45256174173642805,-0.013858605375158513,0.37789124027862775,-0.3867903586863053,0.16243171108876198,0.16243171108876198,-0.23078025553282336,0.11498437510700303,0.7261314845184232,1.474920572686217,-0.6212288478544631,0.3476949375688096,0.6980630201166272,-0.3342348331799229,-0.5661333020712928,-0.7332884144977851,-0.6583020446262418,0.09906477879078189,0.30204211533490194,-0.6027955681655673,0.17814470796339205,0.5406573616707142,0.2404909124205327,-0.1967746802526644,1.3784966610797764,2.8451205119843253,-0.013858605375158513,-0.09615352598164383,0.2713647192914942,-0.9258411670371093
3,069
External side of plasma membrane
13
22
2.795828
0.005177
P07237,P42892,P51790,O75955,P41440,P00813,O96005,O15439,P02786,P08183,P11279,P55899,P04083
Localization
GO Cellular component
msigdb_gocc
512,68,329,551,269,492,144,278,181,152,374,157,599
278,551,144,1771,492,181,599,1128,512,152,374,966,2131,2745,269,68,1776,329,157,1299,634,973
1.2550845585859318,0.6128502332132403,1.9612496555436207,-0.28223504260053384,0.7121179729480956,1.7750896222834918,0.5406573616707142,0.06706796620069248,0.669827883440752,1.9072797273295248,0.931509813270278,0.17814470796339205,-0.45774800066276633,-0.847927384389837,1.304842448283804,2.7561169853489744,-0.28223504260053384,1.0766380800365236,1.8855117311614753,-0.030206765888258928,0.4968122165583206,0.17814470796339205
3,069
Carboxylic acid transport
15
35
2.794588
0.005197
Q9Y619,Q8TDW0,P53985,Q9BQT8,Q9H2J7,P41440,P30825,P07602,O15439,Q15041,Q9UBX3,Q9NZJ7,Q9UJS0,Q96NB2,P04083
Processes and pathways
GO Biological process
msigdb_gobp
131,522,202,75,204,269,120,48,278,499,56,256,547,413,599
278,819,1125,2375,1463,599,1128,48,909,2964,1912,836,120,269,1262,202,1338,1644,499,2765,617,1926,898,522,1065,413,665,75,204,769,256,56,547,1458,131
1.2550845585859318,0.30204211533490194,0.06706796620069248,-0.6027955681655673,-0.1294642520833557,0.5406573616707142,0.06706796620069248,2.9924252844164885,0.22497962854566572,-1.250173600739404,-0.3516910545716578,0.2867278246330759,2.1709437111682344,1.304842448283804,-0.013858605375158513,1.6158927888366963,-0.06306863218986276,-0.21374796024844483,0.6980630201166272,-0.8672923859684633,0.5260869274788118,-0.3516910545716578,0.2404909124205327,0.655647241447091,0.11498437510700303,0.836774272954116,0.4673573625937165,2.6836037582923837,1.6043080729323946,0.36281679569392605,1.3784966610797764,2.8451205119843253,0.6271586509706826,-0.11278048268758513,2.0462929128969036
3,069
Abnormality of the mitochondrion
29
92
2.793598
0.005213
Q9Y2R0,Q9P0J0,P35637,P21912,Q9GZY8,Q9Y584,Q3ZCQ8,Q9Y6M9,P13073,O43676,P23786,Q70HW3,Q9H845,P12235,P00846,Q86Y39,Q9UBX3,O75306,Q9UMS0,Q7KZN9,O75880,Q96RP9,Q9BUB7,O96000,Q96CU9,P00403,Q8N183,P03915,O43772
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
11,271,280,158,544,32,541,161,538,38,166,39,168,553,42,179,56,437,460,331,463,342,469,225,230,108,501,242,116
679,2717,1422,1218,38,1288,116,1836,437,2312,1429,463,1947,225,108,42,242,1196,776,2317,1733,682,553,538,2097,2132,778,158,2794,166,2777,2899,2507,1606,280,2351,2169,1319,2258,1174,874,2797,1081,1434,1177,1226,1964,1263,913,1786,2683,934,2519,560,541,1443,625,1888,1647,1270,39,331,2206,2005,179,501,1929,2487,1796,230,785,342,2851,2047,833,469,544,168,606,904,1870,271,2403,56,460,2914,11,717,1462,865,32,161
0.43772031258177796,-0.828637115565359,-0.11278048268758513,0.002434827265685641,3.143192229979514,-0.030206765888258928,2.2218852461661323,-0.3168403575565848,0.7955852218137351,-0.5661333020712928,-0.11278048268758513,0.7540350803801485,-0.3692094267674327,1.4987164375383368,2.3319722280450734,3.034827813634531,1.4269590798007796,0.018673868634717674,0.3476949375688096,-0.5661333020712928,-0.26502341218255865,0.43772031258177796,0.6128502332132403,0.6271586509706826,-0.439912661259074,-0.45774800066276633,0.3476949375688096,1.8745887034572348,-0.9062487336772611,1.8526640136185266,-0.8867326554727312,-1.0853969322237222,-0.6769429135129599,-0.1967746802526644,1.2550845585859318,-0.5844305409591135,-0.4756480043806108,-0.04660999391817365,-0.529740355465412,0.0348588523240148,0.255952511861343,-0.9062487336772611,0.09906477879078189,-0.11278048268758513,0.0348588523240148,0.002434827265685641,-0.3692094267674327,-0.013858605375158513,0.22497962854566572,-0.28223504260053384,-0.79027866305354,0.2094183652836215,-0.6769429135129599,0.5984987511004508,0.6271586509706826,-0.11278048268758513,0.5114719629049498,-0.3342348331799229,-0.21374796024844483,-0.013858605375158513,3.0768243981140175,1.0766380800365236,-0.4936131056899879,-0.3867903586863053,1.7862524375899929,0.6980630201166272,-0.3516910545716578,-0.6583020446262418,-0.28223504260053384,1.474920572686217,0.3476949375688096,1.0505819654024655,-0.9652573139184435,-0.404434263179806,0.30204211533490194,0.7540350803801485,0.6271586509706826,1.8526640136185266,0.5406573616707142,0.2404909124205327,-0.3168403575565848,1.2924526686835236,-0.6027955681655673,2.8451205119843253,0.7679256085196353,-1.0853969322237222,3.677076391361871,0.4078989792455411,-0.11278048268758513,0.2713647192914942,3.248934240656014,1.8745887034572348
3,069
Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen
10
29
2.793517
0.005214
Q15800,P30519,Q8NB78,Q14534,O15121,Q16850,Q9BU89,Q6UW02,P09601,P13674
Functions
GO Molecular function
msigdb_gomf
97,6,332,301,205,243,147,21,88,350
2059,205,497,1518,1193,1803,1219,512,88,350,351,2761,6,1039,1849,2074,301,97,243,826,21,2484,2686,1578,332,147,1862,2270,2562
-0.42214155708180023,1.5926941854384824,0.6980630201166272,-0.16300366701431568,0.018673868634717674,-0.2995072265011157,0.002434827265685641,0.669827883440752,2.4874342296963574,1.0243805753397968,1.0243805753397968,-0.8672923859684633,3.8691936345199567,0.13085185405757133,-0.3168403575565848,-0.42214155708180023,1.1794390031101867,2.4200817299635164,1.414890812147365,0.30204211533490194,3.506338746109396,-0.6583020446262418,-0.79027866305354,-0.17986003989876528,1.0766380800365236,1.950506657749701,-0.3168403575565848,-0.529740355465412,-0.6956539386154175
3,069
Cytochrome complex assembly
7
13
2.790064
0.00527
Q8N8Q8,P53701,Q7KZN9,Q69YU5,Q6DKK2,Q9Y2R0,Q15070
Processes and pathways
GO Biological process
msigdb_gobp
389,103,331,43,140,11,143
563,463,969,103,143,1153,43,140,331,389,861,964,11
0.5841039652256301,0.7540350803801485,0.17814470796339205,2.351702020702256,1.9719673804988322,0.05099010895251097,3.034827813634531,1.9933274484979564,1.0766380800365236,0.9046357978310428,0.2713647192914942,0.19380682512269046,3.677076391361871
3,069
Abnormality of hepatobiliary system physiology
22
77
2.783987
0.00537
Q9Y619,Q13510,P56589,Q8N511,P23786,Q9H845,P46100,P00846,P39210,P04062,Q10713,P40855,P35670,Q96RP9,Q96A33,O15118,P38571,Q16625,Q6NUQ1,P03915,O43772,Q5XKP0
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
131,139,273,23,166,168,296,42,300,45,177,316,195,342,211,91,221,227,111,242,116,244
1664,91,497,116,563,2614,437,361,1988,42,1127,242,45,2095,1430,910,776,682,668,911,166,836,2166,195,2351,2700,221,300,1808,316,1319,2916,2258,296,970,2198,2451,2889,1779,273,2875,670,1744,177,2575,139,2293,1574,227,1854,560,244,111,897,2205,23,573,2487,211,1894,1023,342,406,833,168,3036,1867,2463,1591,1455,2983,964,1459,1462,1095,948,131
-0.23078025553282336,2.449071204722446,0.6980630201166272,2.2218852461661323,0.5841039652256301,-0.7522128562660492,0.7955852218137351,0.97153594878527,-0.3867903586863053,3.034827813634531,0.06706796620069248,1.4269590798007796,3.017915919263261,-0.439912661259074,-0.11278048268758513,0.22497962854566572,0.3476949375688096,0.43772031258177796,0.45256174173642805,0.22497962854566572,1.8526640136185266,0.2867278246330759,-0.4756480043806108,1.6619426173233864,-0.5844305409591135,-0.8094210498506128,1.5223905970530132,1.1794390031101867,-0.2995072265011157,1.1283203698531714,-0.04660999391817365,-1.1057021297619256,-0.529740355465412,1.1921319124623524,0.17814470796339205,-0.4936131056899879,-0.6397308488356486,-1.065173276993352,-0.28223504260053384,1.280029869062608,-1.0249681947485962,0.45256174173642805,-0.26502341218255865,1.7862524375899929,-0.7144356079504978,1.9933274484979564,-0.5479033919239744,-0.17986003989876528,1.4987164375383368,-0.3168403575565848,0.5984987511004508,1.4027910875879954,2.2521766001450425,0.2404909124205327,-0.4936131056899879,3.475941491201594,0.5841039652256301,-0.6583020446262418,1.5693783522525775,-0.3342348331799229,0.14666752913432865,1.0505819654024655,0.8640358745112992,0.30204211533490194,1.8526640136185266,-1.756049079272557,-0.3168403575565848,-0.6397308488356486,-0.17986003989876528,-0.11278048268758513,-1.2922208324243658,0.19380682512269046,-0.11278048268758513,-0.11278048268758513,0.09906477879078189,0.2094183652836215,2.0462929128969036
3,069
Molecular transducer activity
18
35
2.782351
0.005397
Q99523,O15031,Q14108,P10586,Q9Y6I9,Q99720,O15173,Q8WTV0,Q6RW13,Q9UNN8,Q15629,Q99442,P30536,Q15375,Q07954,Q9BUN8,Q08722,O15118
Functions
GO Molecular function
msigdb_gomf
421,382,37,417,105,107,109,16,340,496,51,503,53,338,371,216,347,91
382,91,109,645,1194,1128,417,722,1604,53,1878,1776,2033,371,347,854,37,338,51,617,973,842,340,16,3063,2363,503,421,107,216,2495,2402,534,496,105
0.9180919307885846,2.449071204722446,2.3220747758671,0.4821074349746622,0.018673868634717674,0.06706796620069248,0.8230843533330983,0.39291854449948976,-0.1967746802526644,2.915054362320261,-0.3342348331799229,-0.28223504260053384,-0.404434263179806,0.9448896451261036,1.0374995229846102,0.2713647192914942,3.176002075643978,1.0505819654024655,2.9409961260648005,0.5260869274788118,0.17814470796339205,0.2867278246330759,1.0505819654024655,3.544036436727491,-4.51731391823549,-0.5844305409591135,0.6980630201166272,0.8230843533330983,2.341847947069304,1.5576761325356283,-0.6583020446262418,-0.6027955681655673,0.6414242418555797,0.7121179729480956,2.351702020702256
3,069
Hyperintensity of cerebral white matter on mri
8
20
2.772953
0.005555
Q9BUK6,O43681,P07602,P17900,P10253,O75503,Q9NZJ7,P21912
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
324,298,48,117,85,58,256,158
298,2773,58,48,1490,85,1363,117,967,158,1667,1469,2199,352,2261,1681,486,2334,324,256
1.1794390031101867,-0.8867326554727312,2.8363003459677576,2.9924252844164885,-0.14620519285903205,2.5064930869004933,-0.07958302654545266,2.2218852461661323,0.17814470796339205,1.8745887034572348,-0.23078025553282336,-0.1294642520833557,-0.4936131056899879,1.0243805753397968,-0.529740355465412,-0.23078025553282336,0.7261314845184232,-0.5661333020712928,1.11545308586704,1.3784966610797764
3,069
Decreased activity of mitochondrial complex i
8
34
2.769647
0.005612
Q9Y584,Q9Y6M9,O96000,O43676,Q70HW3,Q9H845,Q86Y39,Q9UBX3
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
32,161,225,38,39,168,179,56
679,38,1836,437,2312,1429,225,2132,2899,1174,2797,1434,1177,1226,1888,1647,39,179,501,1929,1796,230,785,342,833,168,606,904,1870,56,717,1462,32,161
0.43772031258177796,3.143192229979514,-0.3168403575565848,0.7955852218137351,-0.5661333020712928,-0.11278048268758513,1.4987164375383368,-0.45774800066276633,-1.0853969322237222,0.0348588523240148,-0.9062487336772611,-0.11278048268758513,0.0348588523240148,0.002434827265685641,-0.3342348331799229,-0.21374796024844483,3.0768243981140175,1.7862524375899929,0.6980630201166272,-0.3516910545716578,-0.28223504260053384,1.474920572686217,0.3476949375688096,1.0505819654024655,0.30204211533490194,1.8526640136185266,0.5406573616707142,0.2404909124205327,-0.3168403575565848,2.8451205119843253,0.4078989792455411,-0.11278048268758513,3.248934240656014,1.8745887034572348
3,069
Alcohol binding
6
16
2.765895
0.005677
Q14108,P45880,P21796,O95772,P30536,O15118
Functions
GO Molecular function
msigdb_gomf
37,8,15,80,53,91
2970,91,1255,989,1602,80,721,15,1636,2761,53,600,8,37,2937,237
-1.271153586891543,2.449071204722446,-0.013858605375158513,0.16243171108876198,-0.1967746802526644,2.572565986061649,0.39291854449948976,3.551536551149184,-0.21374796024844483,-0.8672923859684633,2.915054362320261,0.5406573616707142,3.7990432016623545,3.176002075643978,-1.1671130876239315,1.4510018447343276
3,069
Azurophil granule
20
69
2.765188
0.005689
P10619,Q9NQX7,P42785,Q8NF37,O00584,P06280,O43681,P07602,Q9H7Z7,P15586,Q9BTY2,P13473,Q07065,O15260,P16278,P06865,P10253,P17900,P11279,Q9NZJ7
Localization
GO Cellular component
msigdb_gocc
20,150,22,154,289,295,298,48,305,303,186,187,319,322,203,328,85,117,374,256
2468,289,1559,322,608,298,719,1313,871,1909,658,295,328,1195,1143,48,775,454,85,20,2130,374,187,303,203,117,609,1839,2863,1808,22,2450,1669,376,1640,929,2511,2259,1321,1263,1671,569,693,2233,877,319,659,1103,1968,1750,1089,154,629,1717,686,1860,811,2338,3049,186,3009,712,305,150,698,2559,256,1307,2440
-0.6583020446262418,1.2300052027613868,-0.17986003989876528,1.11545308586704,0.5260869274788118,1.1794390031101867,0.39291854449948976,-0.04660999391817365,0.255952511861343,-0.3516910545716578,0.4673573625937165,1.1921319124623524,1.0766380800365236,0.018673868634717674,0.05099010895251097,2.9924252844164885,0.3476949375688096,0.7679256085196353,2.5064930869004933,3.506338746109396,-0.45774800066276633,0.931509813270278,1.7301647060416219,1.16671156823295,1.6043080729323946,2.2218852461661323,0.5260869274788118,-0.3168403575565848,-1.0049855843887756,-0.2995072265011157,3.4835609026263072,-0.6397308488356486,-0.23078025553282336,0.931509813270278,-0.21374796024844483,0.2094183652836215,-0.6769429135129599,-0.529740355465412,-0.04660999391817365,-0.013858605375158513,-0.23078025553282336,0.5841039652256301,0.4228328131433475,-0.511643742111834,0.255952511861343,1.1283203698531714,0.4673573625937165,0.08309274884485632,-0.3692094267674327,-0.26502341218255865,0.09906477879078189,1.9072797273295248,0.5114719629049498,-0.24787194526949927,0.43772031258177796,-0.3168403575565848,0.3173078764001649,-0.5661333020712928,-2.3171592950696214,1.7414372304609023,-1.4421921442388042,0.4078989792455411,1.1539494344082741,1.928944402879871,0.4228328131433475,-0.6956539386154175,1.3784966610797764,-0.030206765888258928,-0.6212288478544631
3,069
protein modifying enzyme
7
21
2.762835
0.00573
P50897,Q9UMR5,Q92791,P51812,O60725,O60678,Q15418
Functions
Panther Protein class
panther_protein_class
13,46,239,50,92,190,254
2059,1516,2498,497,1193,190,92,1256,350,13,50,1849,2074,2628,254,2006,1751,239,1383,46,1904
-0.42214155708180023,-0.16300366701431568,-0.6769429135129599,0.6980630201166272,0.018673868634717674,1.7188644434211229,2.449071204722446,-0.013858605375158513,1.0243805753397968,3.6110714012320395,2.966785889150992,-0.3168403575565848,-0.42214155708180023,-0.7522128562660492,1.3784966610797764,-0.3867903586863053,-0.26502341218255865,1.4389960408956042,-0.07958302654545266,3.017915919263261,-0.3342348331799229
3,069
Loss of speech
6
17
2.760709
0.005768
O43681,P50897,P07602,P17900,O15118,Q9NZJ7
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
298,13,48,117,91,256
1559,91,298,1358,1602,48,117,13,2383,330,1263,2141,2482,671,1622,256,1983
-0.17986003989876528,2.449071204722446,1.1794390031101867,-0.07958302654545266,-0.1967746802526644,2.9924252844164885,2.2218852461661323,3.6110714012320395,-0.6027955681655673,1.0766380800365236,-0.013858605375158513,-0.45774800066276633,-0.6583020446262418,0.45256174173642805,-0.1967746802526644,1.3784966610797764,-0.3692094267674327
3,069
Membrane lipid catabolic process
6
12
2.760637
0.005769
O95470,P06280,Q13510,P50897,P04062,P17900
Processes and pathways
GO Biological process
msigdb_gobp
194,295,139,13,45,117
194,45,658,295,328,775,117,13,877,139,653,986
1.6619426173233864,3.017915919263261,0.4673573625937165,1.1921319124623524,1.0766380800365236,0.3476949375688096,2.2218852461661323,3.6110714012320395,0.255952511861343,1.9933274484979564,0.4821074349746622,0.17814470796339205
3,069
Hydrolase activity hydrolyzing o glycosyl compounds
9
20
2.756372
0.005845
Q9NUJ1,P06280,P16278,P04062,P17900,P10253,Q9BTY2,O60502,P54802
Functions
GO Molecular function
msigdb_gomf
137,295,203,45,117,85,186,156,222
1559,156,45,658,295,328,775,454,85,203,117,2509,222,960,2293,2262,1343,186,137,2914
-0.17986003989876528,1.8855117311614753,3.017915919263261,0.4673573625937165,1.1921319124623524,1.0766380800365236,0.3476949375688096,0.7679256085196353,2.5064930869004933,1.6043080729323946,2.2218852461661323,-0.6769429135129599,1.5223905970530132,0.19380682512269046,-0.5479033919239744,-0.529740355465412,-0.06306863218986276,1.7414372304609023,2.025180715051222,-1.0853969322237222
3,069
Ion homeostasis
35
108
2.734162
0.006254
Q96AQ8,P30519,Q15904,P50897,P62942,Q9Y6M7,Q8NE01,P05023,Q8N511,Q9H4I9,Q9Y5X3,Q93050,Q9Y487,P30536,P02786,Q9UM00,O75503,Q8TAD4,Q9HD20,Q6P4Q7,O43819,P35670,P51790,P30626,Q9BPX6,O75880,Q8WWC4,Q96A33,P09601,Q15043,Q8NEW0,P16615,P51572,Q96HE7,Q8IYU8
Processes and pathways
GO Biological process
msigdb_gobp
514,6,266,13,392,536,530,404,23,24,549,163,562,53,181,576,58,60,61,320,563,195,329,578,343,463,210,211,88,352,101,249,377,251,384
2942,2373,2311,563,2535,1012,1013,58,463,2921,1770,591,1634,1562,181,2838,1221,404,1098,1395,908,775,1055,721,2282,88,2500,3028,2447,2840,1734,2283,249,2793,2742,1169,683,2955,2322,1018,2745,2136,1839,6,53,578,195,2678,1336,851,13,1739,377,329,2140,1338,1180,1082,392,2651,993,670,2423,1375,633,2234,1707,741,352,1788,266,661,320,2429,384,2486,23,530,1580,101,60,210,1154,163,211,514,765,251,2115,652,343,1025,1246,1452,24,61,984,2496,1594,1939,1309,576,562,865,549,2895,1389,536
-1.2084727595847877,-0.6027955681655673,-0.5661333020712928,0.5841039652256301,-0.6956539386154175,0.14666752913432865,0.14666752913432865,2.8363003459677576,0.7540350803801485,-1.1260894774260504,-0.28223504260053384,0.5551835148202413,-0.21374796024844483,-0.17986003989876528,1.7750896222834918,-0.9652573139184435,0.002434827265685641,0.8640358745112992,0.08309274884485632,-0.09615352598164383,0.22497962854566572,0.3476949375688096,0.11498437510700303,0.39291854449948976,-0.5479033919239744,2.4874342296963574,-0.6769429135129599,-1.6871559429488037,-0.6397308488356486,-0.9652573139184435,-0.26502341218255865,-0.5479033919239744,1.390659754720825,-0.9062487336772611,-0.847927384389837,0.0348588523240148,0.43772031258177796,-1.2292802103878024,-0.5661333020712928,0.14666752913432865,-0.847927384389837,-0.45774800066276633,-0.3168403575565848,3.8691936345199567,2.915054362320261,0.5696656342376731,1.6619426173233864,-0.79027866305354,-0.06306863218986276,0.2713647192914942,3.6110714012320395,-0.26502341218255865,0.931509813270278,1.0766380800365236,-0.45774800066276633,-0.06306863218986276,0.0348588523240148,0.09906477879078189,0.8911412130144085,-0.7712094363609074,0.16243171108876198,0.45256174173642805,-0.6212288478544631,-0.07958302654545266,0.4968122165583206,-0.511643742111834,-0.24787194526949927,0.37789124027862775,1.0243805753397968,-0.28223504260053384,1.317199369207603,0.4673573625937165,1.1283203698531714,-0.6212288478544631,0.9180919307885846,-0.6583020446262418,3.475941491201594,0.6414242418555797,-0.17986003989876528,2.3615345361909066,2.818607017092348,1.5693783522525775,0.05099010895251097,1.863639502869007,1.5693783522525775,0.669827883440752,0.36281679569392605,1.390659754720825,-0.439912661259074,0.4821074349746622,1.0505819654024655,0.14666752913432865,0.002434827265685641,-0.11278048268758513,3.475941491201594,2.8008425897497315,0.17814470796339205,-0.6583020446262418,-0.17986003989876528,-0.3516910545716578,-0.030206765888258928,0.5841039652256301,0.5984987511004508,0.2713647192914942,0.6271586509706826,-1.065173276993352,-0.07958302654545266,0.6414242418555797
3,069
Organic anion transmembrane transporter activity
19
32
2.732924
0.006277
Q9Y619,P41440,Q9Y6M7,Q96QD8,O15439,Q9UJS0,Q96NB2,P12235,Q6NUK1,Q9UBX3,P12236,P53985,Q9BQT8,O00400,Q99808,Q8TB61,Q15758,Q9HC21,P30825
Functions
GO Molecular function
msigdb_gomf
131,269,536,665,278,547,413,553,441,56,565,202,75,700,731,83,617,488,120
700,278,950,1125,1463,1054,909,3051,553,565,120,269,1262,202,1644,879,617,441,1926,898,83,413,665,731,75,769,488,56,547,1458,131,536
0.4078989792455411,1.2550845585859318,0.19380682512269046,0.06706796620069248,-0.1294642520833557,0.11498437510700303,0.22497962854566572,-2.421230489514741,0.6128502332132403,0.5841039652256301,2.1709437111682344,1.304842448283804,-0.013858605375158513,1.6158927888366963,-0.21374796024844483,0.255952511861343,0.5260869274788118,0.7955852218137351,-0.3516910545716578,0.2404909124205327,2.525471026963564,0.836774272954116,0.4673573625937165,0.39291854449948976,2.6836037582923837,0.36281679569392605,0.7261314845184232,2.8451205119843253,0.6271586509706826,-0.11278048268758513,2.0462929128969036,0.6414242418555797
3,069
Organic acid transmembrane transport
13
31
2.720898
0.00651
Q9Y619,P23786,Q8TDW0,P53985,Q9BQT8,Q9H2J7,P41440,P30825,O43772,Q15041,P08183,Q9UBX3,Q96NB2
Processes and pathways
GO Biological process
msigdb_gobp
131,166,522,202,75,204,269,120,116,499,152,56,413
116,819,1125,2375,1463,1128,152,909,3051,166,836,120,692,269,970,1262,202,1644,499,617,898,522,413,665,75,204,769,56,547,1458,131
2.2218852461661323,0.30204211533490194,0.06706796620069248,-0.6027955681655673,-0.1294642520833557,0.06706796620069248,1.9072797273295248,0.22497962854566572,-2.421230489514741,1.8526640136185266,0.2867278246330759,2.1709437111682344,0.4228328131433475,1.304842448283804,0.17814470796339205,-0.013858605375158513,1.6158927888366963,-0.21374796024844483,0.6980630201166272,0.5260869274788118,0.2404909124205327,0.655647241447091,0.836774272954116,0.4673573625937165,2.6836037582923837,1.6043080729323946,0.36281679569392605,2.8451205119843253,0.6271586509706826,-0.11278048268758513,2.0462929128969036
3,069
Toe walking
7
21
2.719807
0.006532
O43681,Q99720,Q8TD16,P07602,P35637,Q9NZJ7,P50402
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
298,107,208,48,280,256,317
298,564,598,1465,48,280,1319,317,1262,330,1263,2451,1745,2234,1891,208,1113,107,832,256,1558
1.1794390031101867,0.5841039652256301,0.5406573616707142,-0.1294642520833557,2.9924252844164885,1.2550845585859318,-0.04660999391817365,1.1283203698531714,-0.013858605375158513,1.0766380800365236,-0.013858605375158513,-0.6397308488356486,-0.26502341218255865,-0.511643742111834,-0.3342348331799229,1.5926941854384824,0.08309274884485632,2.341847947069304,0.30204211533490194,1.3784966610797764,-0.16300366701431568
3,069
Paraparesis
7
24
2.718251
0.006563
Q9Y619,Q13510,Q6DKK2,P04062,Q5XKP0,Q9H6K4,P21912
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
131,139,140,45,244,89,158
1358,2898,2409,45,1912,158,1606,280,1263,2141,2512,1572,1786,139,2001,244,140,997,89,1626,1983,865,948,131
-0.07958302654545266,-1.0853969322237222,-0.6212288478544631,3.017915919263261,-0.3516910545716578,1.8745887034572348,-0.1967746802526644,1.2550845585859318,-0.013858605375158513,-0.45774800066276633,-0.6769429135129599,-0.17986003989876528,-0.28223504260053384,1.9933274484979564,-0.3867903586863053,1.4027910875879954,1.9933274484979564,0.16243171108876198,2.4874342296963574,-0.1967746802526644,-0.3692094267674327,0.2713647192914942,0.2094183652836215,2.0462929128969036
3,069
Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins
20
63
2.712662
0.006675
Q8N8Q8,Q9P0J0,P21912,Q9Y6M9,P13073,O43676,Q9H845,P00846,Q86Y39,Q9UDW1,O75306,O43819,P24539,O14949,O75880,O75964,O96000,P00403,Q8N183,P03915
Processes and pathways
Reactome Pathways
msigdb_reactome
389,271,158,161,538,38,168,42,179,57,437,563,448,70,463,93,225,108,501,242
679,1218,70,1945,38,1288,563,1836,437,2312,1429,463,1520,93,590,1947,225,108,42,242,908,910,1951,1167,538,2097,1198,2098,2132,778,158,668,448,1956,2899,1606,1315,928,2169,2258,969,2865,2797,1434,1059,840,1705,934,881,2519,179,501,389,1929,766,833,168,904,1870,271,57,717,161
0.43772031258177796,0.002434827265685641,2.7380995161851818,-0.3692094267674327,3.143192229979514,-0.030206765888258928,0.5841039652256301,-0.3168403575565848,0.7955852218137351,-0.5661333020712928,-0.11278048268758513,0.7540350803801485,-0.16300366701431568,2.449071204722446,0.5551835148202413,-0.3692094267674327,1.4987164375383368,2.3319722280450734,3.034827813634531,1.4269590798007796,0.22497962854566572,0.22497962854566572,-0.3692094267674327,0.0348588523240148,0.6271586509706826,-0.439912661259074,0.018673868634717674,-0.439912661259074,-0.45774800066276633,0.3476949375688096,1.8745887034572348,0.45256174173642805,0.781775583130449,-0.3692094267674327,-1.0853969322237222,-0.1967746802526644,-0.04660999391817365,0.2094183652836215,-0.4756480043806108,-0.529740355465412,0.17814470796339205,-1.0049855843887756,-0.9062487336772611,-0.11278048268758513,0.11498437510700303,0.2867278246330759,-0.24787194526949927,0.2094183652836215,0.255952511861343,-0.6769429135129599,1.7862524375899929,0.6980630201166272,0.9046357978310428,-0.3516910545716578,0.36281679569392605,0.30204211533490194,1.8526640136185266,0.2404909124205327,-0.3168403575565848,1.2924526686835236,2.8451205119843253,0.4078989792455411,1.8745887034572348
3,069
Abnormal circulating cholesterol concentration
11
29
2.710664
0.006715
Q15392,Q15800,Q15904,P37268,Q9NVI7,P34913,P07602,Q8N511,Q9NZJ7,P38571,P50402
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
96,97,266,232,364,362,48,23,256,221,317
681,598,2619,48,362,232,221,1336,1367,317,2704,725,1676,1747,2234,614,96,1378,97,266,23,1113,832,3036,364,256,366,547,1557
0.43772031258177796,0.5406573616707142,-0.7522128562660492,2.9924252844164885,0.97153594878527,1.462976639584121,1.5223905970530132,-0.06306863218986276,-0.07958302654545266,1.1283203698531714,-0.8094210498506128,0.39291854449948976,-0.23078025553282336,-0.26502341218255865,-0.511643742111834,0.5260869274788118,2.4297657388802323,-0.07958302654545266,2.4200817299635164,1.317199369207603,3.475941491201594,0.08309274884485632,0.30204211533490194,-1.756049079272557,0.97153594878527,1.3784966610797764,0.9582316246880604,0.6271586509706826,-0.16300366701431568
3,069
calmodulin-related
7
12
2.693939
0.007061
P41208,Q14257,O43852,Q02818,Q9BPX6,P80303,Q8IYU8
Functions
Panther Protein class
panther_protein_class
252,66,164,2,343,55,384
164,2447,578,1293,252,55,2,66,430,384,885,343
1.8526640136185266,-0.6397308488356486,0.5696656342376731,-0.030206765888258928,1.3784966610797764,2.862708171124781,4.125669255470878,2.774061482172853,0.8093547404733235,0.9180919307885846,0.255952511861343,1.0505819654024655
3,069
Inorganic anion transmembrane transporter activity
9
22
2.692132
0.0071
P45880,Q9Y277,O43681,P51790,P21796,O15439,Q9UBX3,Q9NW15,Q9C0H2
Functions
GO Molecular function
msigdb_gomf
8,138,298,329,15,278,56,281,26
1944,278,298,3028,15,8,329,1568,1338,1644,352,626,618,898,522,26,281,56,138,2895,1389,536
-0.3692094267674327,1.2550845585859318,1.1794390031101867,-1.6871559429488037,3.551536551149184,3.7990432016623545,1.0766380800365236,-0.17986003989876528,-0.06306863218986276,-0.21374796024844483,1.0243805753397968,0.5114719629049498,0.5260869274788118,0.2404909124205327,0.655647241447091,3.344313892455025,1.2550845585859318,2.8451205119843253,2.0145877281129803,-1.065173276993352,-0.07958302654545266,0.6414242418555797
3,069
Outer mitochondrial membrane protein complex
9
15
2.679852
0.007365
Q9NS69,Q8IWA4,Q13505,Q9Y512,O96008,Q5XKP0,Q9NX63,Q8N4H5,Q5HYI7
Localization
GO Cellular component
msigdb_gocc
4,327,104,367,399,244,445,25,223
681,757,399,2415,104,661,223,244,519,327,25,4,1030,445,367
0.43772031258177796,0.36281679569392605,0.8776079734066499,-0.6212288478544631,2.351702020702256,0.4673573625937165,1.5105686587244185,1.4027910875879954,0.655647241447091,1.0896121215347725,3.445328693074278,4.125669255470878,0.14666752913432865,0.7955852218137351,0.9582316246880604
3,069
Incoordination
15
67
2.669946
0.007586
Q9Y619,O14773,P35670,O43681,Q13510,Q6DKK2,Q9NR77,P04062,P00846,P07602,Q10713,Q01105,O75503,Q9NZJ7,P21912
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
131,67,195,298,139,140,12,45,42,48,177,81,58,256,158
314,2853,1559,67,2127,2871,298,563,1313,2773,58,2642,835,2590,42,45,1465,48,553,2862,158,1469,1606,1470,195,2286,1319,1336,761,1567,1262,1263,2451,2141,1322,81,2598,2386,177,139,633,2234,1968,409,1970,672,1889,140,1856,2909,2263,2687,1581,1893,2303,1067,2851,12,1626,256,459,2612,2213,1594,2439,1486,131
1.1283203698531714,-0.9850821494668925,-0.17986003989876528,2.7650983212483924,-0.45774800066276633,-1.0249681947485962,1.1794390031101867,0.5841039652256301,-0.04660999391817365,-0.8867326554727312,2.8363003459677576,-0.7712094363609074,0.2867278246330759,-0.7332884144977851,3.034827813634531,3.017915919263261,-0.1294642520833557,2.9924252844164885,0.6128502332132403,-1.0049855843887756,1.8745887034572348,-0.1294642520833557,-0.1967746802526644,-0.1294642520833557,1.6619426173233864,-0.5479033919239744,-0.04660999391817365,-0.06306863218986276,0.36281679569392605,-0.17986003989876528,-0.013858605375158513,-0.013858605375158513,-0.6397308488356486,-0.45774800066276633,-0.04660999391817365,2.563186671331025,-0.7332884144977851,-0.6027955681655673,1.7862524375899929,1.9933274484979564,0.4968122165583206,-0.511643742111834,-0.3692094267674327,0.8504247102515363,-0.3692094267674327,0.45256174173642805,-0.3342348331799229,1.9933274484979564,-0.3168403575565848,-1.0853969322237222,-0.529740355465412,-0.79027866305354,-0.17986003989876528,-0.3342348331799229,-0.5479033919239744,0.11498437510700303,-0.9652573139184435,3.6331860602374753,-0.1967746802526644,1.3784966610797764,0.7679256085196353,-0.7332884144977851,-0.4936131056899879,-0.17986003989876528,-0.6212288478544631,-0.1294642520833557,2.0462929128969036
3,069
Hormone metabolic process
12
30
2.661046
0.00779
P16435,O95470,P42892,Q9HB40,Q6NUM9,O75844,Q9UBM7,P05023,P30536,Q96HE7,Q8TAD4,O60678
Processes and pathways
GO Biological process
msigdb_gobp
351,194,68,7,134,73,366,404,53,251,60,190
190,73,756,194,404,966,2412,351,53,68,2648,1261,3017,2798,2550,695,134,444,829,60,1581,574,251,2851,675,7,748,366,1385,751
1.7188644434211229,2.71093528756688,0.36281679569392605,1.6619426173233864,0.8640358745112992,0.17814470796339205,-0.6212288478544631,1.0243805753397968,2.915054362320261,2.7561169853489744,-0.7712094363609074,-0.013858605375158513,-1.5299171060170624,-0.9062487336772611,-0.6956539386154175,0.4228328131433475,2.025180715051222,0.7955852218137351,0.30204211533490194,2.818607017092348,-0.17986003989876528,0.5841039652256301,1.390659754720825,-0.9652573139184435,0.45256174173642805,3.841271916977857,0.37789124027862775,0.9582316246880604,-0.07958302654545266,0.37789124027862775
3,069
Establishment of protein localization to mitochondrial membrane
10
19
2.653629
0.007963
O14737,Q9Y584,Q9Y5J9,Q9NS69,P62072,Q9Y512,Q15070,Q9P0J0,Q8WWC4,O60220
Processes and pathways
GO Biological process
msigdb_gobp
381,32,258,4,35,367,143,271,210,335
2942,381,335,757,2315,2447,2762,2795,35,143,827,389,210,4,271,964,367,32,258
-1.2084727595847877,0.9180919307885846,1.0505819654024655,0.36281679569392605,-0.5661333020712928,-0.6397308488356486,-0.8672923859684633,-0.9062487336772611,3.2085671141055583,1.9719673804988322,0.30204211533490194,0.9046357978310428,1.5693783522525775,4.125669255470878,1.2924526686835236,0.19380682512269046,0.9582316246880604,3.248934240656014,1.366301653124708
3,069
Calcium ion import
6
12
2.650843
0.008029
O75844,P21796,Q9BPX6,Q8WWC4,Q9H4I9,P16615
Processes and pathways
GO Biological process
msigdb_gobp
73,15,343,210,24,249
774,73,249,15,1916,384,1580,210,514,343,24,865
0.3476949375688096,2.71093528756688,1.390659754720825,3.551536551149184,-0.3516910545716578,0.9180919307885846,-0.17986003989876528,1.5693783522525775,0.669827883440752,1.0505819654024655,3.475941491201594,0.2713647192914942
3,069
Oxidase
7
19
2.645806
0.00815
Q15800,O15260,P14406,Q9H845,O15254,O43169,Q15067
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
97,322,1,168,263,19,409
263,322,19,563,463,1167,682,2097,1,2098,778,1496,759,874,409,97,1087,1577,168
1.317199369207603,1.11545308586704,3.506338746109396,0.5841039652256301,0.7540350803801485,0.0348588523240148,0.43772031258177796,-0.439912661259074,4.125669255470878,-0.439912661259074,0.3476949375688096,-0.14620519285903205,0.36281679569392605,0.255952511861343,0.8504247102515363,2.4200817299635164,0.09906477879078189,-0.17986003989876528,1.8526640136185266
3,069
Delusions
6
18
2.644771
0.008175
O43681,P04062,P07602,Q13144,P21964,Q9NZJ7
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
298,45,48,217,250,256
1559,298,335,45,48,2674,250,759,1336,1472,1295,217,1886,1348,1901,256,1902,547
-0.17986003989876528,1.1794390031101867,1.0505819654024655,3.017915919263261,2.9924252844164885,-0.79027866305354,1.390659754720825,0.36281679569392605,-0.06306863218986276,-0.1294642520833557,-0.030206765888258928,1.545944193162598,-0.3342348331799229,-0.06306863218986276,-0.3342348331799229,1.3784966610797764,-0.3342348331799229,0.6271586509706826
3,069
Monooxygenase activity
6
9
2.641975
0.008242
Q15800,P30519,Q16850,Q9BU89,Q6UW02,P09601
Functions
GO Molecular function
msigdb_gomf
97,6,243,147,21,88
88,6,1039,301,97,243,21,2686,147
2.4874342296963574,3.8691936345199567,0.13085185405757133,1.1794390031101867,2.4200817299635164,1.414890812147365,3.506338746109396,-0.79027866305354,1.950506657749701
3,069
secondary carrier transporter
9
17
2.641188
0.008262
Q96ES6,Q6NT16,Q9BQT8,Q9Y6M7,Q8TB61,O14975,Q9UBX3,Q9UJS0,Q15043
Functions
Panther Protein class
panther_protein_class
33,27,75,536,83,526,56,547,352
700,526,1125,591,1338,1644,352,27,1926,83,33,75,56,547,1458,2895,536
0.4078989792455411,0.6414242418555797,0.06706796620069248,0.5551835148202413,-0.06306863218986276,-0.21374796024844483,1.0243805753397968,3.3285620139858545,-0.3516910545716578,2.525471026963564,3.2328322525717677,2.6836037582923837,2.8451205119843253,0.6271586509706826,-0.11278048268758513,-1.065173276993352,0.6414242418555797
3,069
Secondary active transmembrane transporter activity
13
24
2.641105
0.008264
Q96ES6,Q15758,P12235,P53985,P51790,P41440,Q9H2J7,Q9Y6M7,Q96QD8,O95202,Q9UBX3,Q15043,P12236
Functions
GO Molecular function
msigdb_gomf
33,617,553,202,329,269,204,536,665,591,56,352,565
700,591,1054,909,553,565,269,329,1568,1262,202,1338,913,1644,352,617,1580,33,665,204,56,1458,2895,536
0.4078989792455411,0.5551835148202413,0.11498437510700303,0.22497962854566572,0.6128502332132403,0.5841039652256301,1.304842448283804,1.0766380800365236,-0.17986003989876528,-0.013858605375158513,1.6158927888366963,-0.06306863218986276,0.22497962854566572,-0.21374796024844483,1.0243805753397968,0.5260869274788118,-0.17986003989876528,3.2328322525717677,0.4673573625937165,1.6043080729323946,2.8451205119843253,-0.11278048268758513,-1.065173276993352,0.6414242418555797
3,069
Oxidoreductase
28
117
2.639285
0.008308
P14406,O15254,Q9P0J0,O43169,P21912,Q9Y6M9,Q9H845,Q14534,Q9H7Z7,Q9UDW1,P30043,Q9NZ01,P00374,O15260,P54886,Q15392,Q15800,Q96CU9,P00403,Q9UBM7,Q8N0U8,O95881,P03915,Q16850,Q8N4Q0,Q9BY49,Q96HE7,Q8TED1
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
1,263,271,19,158,161,168,301,305,57,59,63,64,322,330,96,97,230,108,366,112,369,242,243,118,121,251,385
679,2059,1218,263,322,19,718,2810,1945,1288,563,1767,1836,437,2312,463,2921,756,590,564,369,2345,632,64,1771,108,242,2838,2775,2191,2446,2096,776,1167,682,1197,2195,2097,1494,1,2501,1198,2412,2098,778,158,1397,2221,1496,2899,2900,2863,59,1259,1260,1606,516,2138,2473,759,2169,2065,2323,892,2648,1175,874,2417,1608,1434,2326,2198,330,3008,1041,1849,737,1208,301,614,3040,409,96,97,934,881,2519,243,2856,2752,1087,1577,2005,112,2486,118,3033,2110,1751,2264,1581,385,230,251,2851,1213,121,305,168,770,748,63,271,366,1689,57,161
0.43772031258177796,-0.42214155708180023,0.002434827265685641,1.317199369207603,1.11545308586704,3.506338746109396,0.39291854449948976,-0.9258411670371093,-0.3692094267674327,-0.030206765888258928,0.5841039652256301,-0.28223504260053384,-0.3168403575565848,0.7955852218137351,-0.5661333020712928,0.7540350803801485,-1.1260894774260504,0.36281679569392605,0.5551835148202413,0.5841039652256301,0.9448896451261036,-0.5844305409591135,0.4968122165583206,2.774061482172853,-0.28223504260053384,2.3319722280450734,1.4269590798007796,-0.9652573139184435,-0.8867326554727312,-0.4936131056899879,-0.6397308488356486,-0.439912661259074,0.3476949375688096,0.0348588523240148,0.43772031258177796,0.018673868634717674,-0.4936131056899879,-0.439912661259074,-0.14620519285903205,4.125669255470878,-0.6769429135129599,0.018673868634717674,-0.6212288478544631,-0.439912661259074,0.3476949375688096,1.8745887034572348,-0.09615352598164383,-0.511643742111834,-0.14620519285903205,-1.0853969322237222,-1.0853969322237222,-1.0049855843887756,2.818607017092348,-0.013858605375158513,-0.013858605375158513,-0.1967746802526644,0.655647241447091,-0.45774800066276633,-0.6583020446262418,0.36281679569392605,-0.4756480043806108,-0.42214155708180023,-0.5661333020712928,0.2404909124205327,-0.7712094363609074,0.0348588523240148,0.255952511861343,-0.6212288478544631,-0.1967746802526644,-0.11278048268758513,-0.5661333020712928,-0.4936131056899879,1.0766380800365236,-1.4421921442388042,0.13085185405757133,-0.3168403575565848,0.37789124027862775,0.018673868634717674,1.1794390031101867,0.5260869274788118,-1.8729618416459095,0.8504247102515363,2.4297657388802323,2.4200817299635164,0.2094183652836215,0.255952511861343,-0.6769429135129599,1.414890812147365,-0.9850821494668925,-0.847927384389837,0.09906477879078189,-0.17986003989876528,-0.3867903586863053,2.2521766001450425,-0.6583020446262418,2.2218852461661323,-1.7329818849185776,-0.439912661259074,-0.26502341218255865,-0.529740355465412,-0.17986003989876528,0.9180919307885846,1.474920572686217,1.390659754720825,-0.9652573139184435,0.018673868634717674,2.1606861561903865,1.1539494344082741,1.8526640136185266,0.36281679569392605,0.37789124027862775,2.78300653577057,1.2924526686835236,0.9582316246880604,-0.23078025553282336,2.8451205119843253,1.8745887034572348
3,069
Cellular ion homeostasis
30
86
2.639197
0.00831
Q96AQ8,Q15904,P50897,P62942,Q9Y6M7,P05023,Q8N511,Q9H4I9,Q93050,Q9Y487,P02786,Q9UM00,O75503,Q8TAD4,Q9HD20,O43819,P35670,P51790,P30626,Q9BPX6,O75880,Q8WWC4,Q96A33,P09601,Q15043,Q8NEW0,P16615,P51572,Q96HE7,Q8IYU8
Processes and pathways
GO Biological process
msigdb_gobp
514,266,13,392,536,404,23,24,163,562,181,576,58,60,61,563,195,329,578,343,463,210,211,88,352,101,249,377,251,384
2942,2373,563,2535,1012,1013,58,463,2921,591,1634,1562,181,404,1098,1395,908,775,1055,721,2282,88,3028,2447,2840,1734,2283,249,2793,2742,1169,683,2955,2322,1018,2745,2136,1839,578,195,2678,1336,13,1739,377,329,2140,1338,1180,1082,392,993,633,1707,352,1788,266,661,2429,384,23,1580,101,60,210,1154,163,211,514,765,251,2115,652,343,1246,24,61,2496,1594,1939,1309,576,562,865,1389,536
-1.2084727595847877,-0.6027955681655673,0.5841039652256301,-0.6956539386154175,0.14666752913432865,0.14666752913432865,2.8363003459677576,0.7540350803801485,-1.1260894774260504,0.5551835148202413,-0.21374796024844483,-0.17986003989876528,1.7750896222834918,0.8640358745112992,0.08309274884485632,-0.09615352598164383,0.22497962854566572,0.3476949375688096,0.11498437510700303,0.39291854449948976,-0.5479033919239744,2.4874342296963574,-1.6871559429488037,-0.6397308488356486,-0.9652573139184435,-0.26502341218255865,-0.5479033919239744,1.390659754720825,-0.9062487336772611,-0.847927384389837,0.0348588523240148,0.43772031258177796,-1.2292802103878024,-0.5661333020712928,0.14666752913432865,-0.847927384389837,-0.45774800066276633,-0.3168403575565848,0.5696656342376731,1.6619426173233864,-0.79027866305354,-0.06306863218986276,3.6110714012320395,-0.26502341218255865,0.931509813270278,1.0766380800365236,-0.45774800066276633,-0.06306863218986276,0.0348588523240148,0.09906477879078189,0.8911412130144085,0.16243171108876198,0.4968122165583206,-0.24787194526949927,1.0243805753397968,-0.28223504260053384,1.317199369207603,0.4673573625937165,-0.6212288478544631,0.9180919307885846,3.475941491201594,-0.17986003989876528,2.3615345361909066,2.818607017092348,1.5693783522525775,0.05099010895251097,1.863639502869007,1.5693783522525775,0.669827883440752,0.36281679569392605,1.390659754720825,-0.439912661259074,0.4821074349746622,1.0505819654024655,0.002434827265685641,3.475941491201594,2.8008425897497315,-0.6583020446262418,-0.17986003989876528,-0.3516910545716578,-0.030206765888258928,0.5841039652256301,0.5984987511004508,0.2713647192914942,-0.07958302654545266,0.6414242418555797
3,069
Optic disc pallor
11
49
2.638344
0.008331
Q9Y6M9,O96000,Q9UG56,O43676,Q9H061,Q96CU9,P00846,Q10713,Q86Y39,Q9H6K4,Q6P4Q7
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
161,225,69,38,40,230,42,177,179,89,320
679,1422,1559,774,1391,38,1767,802,1836,437,2312,1428,1429,2020,835,564,225,42,703,2378,1258,2132,2899,2797,1568,2778,177,1103,1153,320,179,3032,501,1929,1447,1505,1893,230,833,324,544,40,89,904,1870,69,717,865,161
0.43772031258177796,-0.11278048268758513,-0.17986003989876528,0.3476949375688096,-0.09615352598164383,3.143192229979514,-0.28223504260053384,0.3173078764001649,-0.3168403575565848,0.7955852218137351,-0.5661333020712928,-0.11278048268758513,-0.11278048268758513,-0.404434263179806,0.2867278246330759,0.5841039652256301,1.4987164375383368,3.034827813634531,0.4078989792455411,-0.6027955681655673,-0.013858605375158513,-0.45774800066276633,-1.0853969322237222,-0.9062487336772611,-0.17986003989876528,-0.8867326554727312,1.7862524375899929,0.08309274884485632,0.05099010895251097,1.1283203698531714,1.7862524375899929,-1.7329818849185776,0.6980630201166272,-0.3516910545716578,-0.11278048268758513,-0.14620519285903205,-0.3342348331799229,1.474920572686217,0.30204211533490194,1.11545308586704,0.6271586509706826,3.0768243981140175,2.4874342296963574,0.2404909124205327,-0.3168403575565848,2.7561169853489744,0.4078989792455411,0.2713647192914942,1.8745887034572348
3,069
Respiratory electron transport
17
53
2.624269
0.008684
Q9Y6M9,O43819,O96000,P13073,Q8N8Q8,O43676,O14949,Q9H845,P00403,Q9P0J0,O75880,Q8N183,P03915,Q86Y39,Q9UDW1,O75306,P21912
Processes and pathways
Reactome Pathways
msigdb_reactome
161,563,225,538,389,38,70,168,108,271,463,501,242,179,57,437,158
679,1218,70,1945,38,1288,563,1836,437,2312,1429,463,590,1947,225,108,242,910,1951,1167,538,2097,1198,2098,2132,778,158,668,2899,1606,1315,2169,2258,969,2797,1434,1705,934,881,2519,179,501,389,1929,766,833,168,904,1870,271,57,717,161
0.43772031258177796,0.002434827265685641,2.7380995161851818,-0.3692094267674327,3.143192229979514,-0.030206765888258928,0.5841039652256301,-0.3168403575565848,0.7955852218137351,-0.5661333020712928,-0.11278048268758513,0.7540350803801485,0.5551835148202413,-0.3692094267674327,1.4987164375383368,2.3319722280450734,1.4269590798007796,0.22497962854566572,-0.3692094267674327,0.0348588523240148,0.6271586509706826,-0.439912661259074,0.018673868634717674,-0.439912661259074,-0.45774800066276633,0.3476949375688096,1.8745887034572348,0.45256174173642805,-1.0853969322237222,-0.1967746802526644,-0.04660999391817365,-0.4756480043806108,-0.529740355465412,0.17814470796339205,-0.9062487336772611,-0.11278048268758513,-0.24787194526949927,0.2094183652836215,0.255952511861343,-0.6769429135129599,1.7862524375899929,0.6980630201166272,0.9046357978310428,-0.3516910545716578,0.36281679569392605,0.30204211533490194,1.8526640136185266,0.2404909124205327,-0.3168403575565848,1.2924526686835236,2.8451205119843253,0.4078989792455411,1.8745887034572348
3,069
Peptide binding
17
72
2.62297
0.008717
Q9Y584,P40855,Q15392,O14773,P61758,Q03519,P42892,P10321,Q9UIQ6,P55786,Q8WTV0,Q9H7Z7,Q07954,Q9NQX7,O00264,P52292,P55899
Functions
GO Molecular function
msigdb_gomf
32,316,96,67,292,261,68,323,100,76,16,305,371,150,214,408,157
1598,214,988,1423,1424,67,537,1141,645,868,757,1127,703,2346,2063,1396,323,966,2927,2568,2745,2136,2137,3020,1960,1200,2746,316,68,2813,1566,2197,1777,408,1526,1178,76,157,1919,912,292,1967,261,371,1183,1785,2425,1375,2146,933,96,843,1446,16,745,2046,2431,1540,653,1620,2117,2050,305,1138,150,1688,1031,1827,424,100,1555,32
-0.1967746802526644,1.5576761325356283,0.16243171108876198,-0.11278048268758513,-0.11278048268758513,2.7650983212483924,0.6271586509706826,0.05099010895251097,0.4821074349746622,0.255952511861343,0.36281679569392605,0.06706796620069248,0.4078989792455411,-0.5844305409591135,-0.42214155708180023,-0.09615352598164383,1.11545308586704,0.17814470796339205,-1.1465595896590495,-0.7144356079504978,-0.847927384389837,-0.45774800066276633,-0.45774800066276633,-1.5743515872010667,-0.3692094267674327,0.018673868634717674,-0.847927384389837,1.1283203698531714,2.7561169853489744,-0.9258411670371093,-0.17986003989876528,-0.4936131056899879,-0.28223504260053384,0.8504247102515363,-0.16300366701431568,0.0348588523240148,2.6376742328100615,1.8855117311614753,-0.3516910545716578,0.22497962854566572,1.2047904684516537,-0.3692094267674327,1.3418152746816723,0.9448896451261036,0.0348588523240148,-0.28223504260053384,-0.6212288478544631,-0.07958302654545266,-0.45774800066276633,0.2094183652836215,2.4297657388802323,0.2867278246330759,-0.11278048268758513,3.544036436727491,0.37789124027862775,-0.404434263179806,-0.6212288478544631,-0.16300366701431568,0.4821074349746622,-0.1967746802526644,-0.439912661259074,-0.404434263179806,1.1539494344082741,0.06706796620069248,1.928944402879871,-0.23078025553282336,0.14666752913432865,-0.2995072265011157,0.8230843533330983,2.3713455802707064,-0.16300366701431568,3.248934240656014
3,069
Glycoside hydrolase superfamily [IPR017853]
8
15
2.6176
0.008855
P06280,P16278,P06865,P04062,P10253,Q9BTY2,O60502,P54802
Sequence
InterPro Superfamily
interpro_homologous_superfamily
295,203,328,45,85,186,156,222
156,45,658,295,328,775,909,454,85,203,2509,222,2293,186,979
1.8855117311614753,3.017915919263261,0.4673573625937165,1.1921319124623524,1.0766380800365236,0.3476949375688096,0.22497962854566572,0.7679256085196353,2.5064930869004933,1.6043080729323946,-0.6769429135129599,1.5223905970530132,-0.5479033919239744,1.7414372304609023,0.17814470796339205
3,069
Microbody membrane
13
29
2.613087
0.008973
P51648,P40855,O00116,Q9NR77,P39210,O75381,P56589,Q8TB36,Q15067,O14975,Q9BY49,Q9UKU0,Q9BTZ2
Localization
GO Cellular component
msigdb_gocc
128,316,218,12,300,361,273,604,409,526,121,282,675
218,526,818,950,2277,361,1948,1493,836,692,2167,300,316,128,1261,273,409,764,1618,1234,996,604,997,1861,675,121,12,282,948
1.5341823947732471,0.6414242418555797,0.30204211533490194,0.19380682512269046,-0.5479033919239744,0.97153594878527,-0.3692094267674327,-0.14620519285903205,0.2867278246330759,0.4228328131433475,-0.4756480043806108,1.1794390031101867,1.1283203698531714,2.056812333710736,-0.013858605375158513,1.280029869062608,0.8504247102515363,0.36281679569392605,-0.1967746802526644,0.002434827265685641,0.16243171108876198,0.5406573616707142,0.16243171108876198,-0.3168403575565848,0.45256174173642805,2.1606861561903865,3.6331860602374753,1.2550845585859318,0.2094183652836215
3,069
Metal ion homeostasis
34
81
2.60387
0.009218
Q96AQ8,Q13586,P30519,Q15904,Q96TC7,P62942,Q8NE01,P05023,Q16891,Q8N511,Q9H4I9,Q9Y5X3,P98170,Q9Y487,P02786,Q9UM00,Q8TAD4,Q9HD20,Q6P4Q7,O43819,P35670,P30626,Q9BPX6,O75880,Q8WWC4,Q96A33,O95202,P09601,Q15043,Q8NEW0,P16615,P51572,Q96HE7,Q8IYU8
Processes and pathways
GO Biological process
msigdb_gobp
514,633,6,266,652,392,530,404,661,23,24,549,670,562,181,576,60,61,320,563,195,578,343,463,210,211,591,88,352,101,249,377,251,384
2942,2373,2311,563,2535,1012,1013,463,2921,591,1634,181,2838,1221,404,1098,1395,775,1055,721,2282,88,2447,1734,2283,249,2793,2742,1169,683,2955,1018,2745,2136,6,578,195,2678,1336,377,2140,1338,1180,1082,392,993,670,2423,1375,633,1707,352,1788,266,661,320,2429,384,23,530,1580,101,60,210,211,514,251,2115,652,343,1025,1246,24,61,2496,1309,576,562,865,549,2895
-1.2084727595847877,-0.6027955681655673,-0.5661333020712928,0.5841039652256301,-0.6956539386154175,0.14666752913432865,0.14666752913432865,0.7540350803801485,-1.1260894774260504,0.5551835148202413,-0.21374796024844483,1.7750896222834918,-0.9652573139184435,0.002434827265685641,0.8640358745112992,0.08309274884485632,-0.09615352598164383,0.3476949375688096,0.11498437510700303,0.39291854449948976,-0.5479033919239744,2.4874342296963574,-0.6397308488356486,-0.26502341218255865,-0.5479033919239744,1.390659754720825,-0.9062487336772611,-0.847927384389837,0.0348588523240148,0.43772031258177796,-1.2292802103878024,0.14666752913432865,-0.847927384389837,-0.45774800066276633,3.8691936345199567,0.5696656342376731,1.6619426173233864,-0.79027866305354,-0.06306863218986276,0.931509813270278,-0.45774800066276633,-0.06306863218986276,0.0348588523240148,0.09906477879078189,0.8911412130144085,0.16243171108876198,0.45256174173642805,-0.6212288478544631,-0.07958302654545266,0.4968122165583206,-0.24787194526949927,1.0243805753397968,-0.28223504260053384,1.317199369207603,0.4673573625937165,1.1283203698531714,-0.6212288478544631,0.9180919307885846,3.475941491201594,0.6414242418555797,-0.17986003989876528,2.3615345361909066,2.818607017092348,1.5693783522525775,1.5693783522525775,0.669827883440752,1.390659754720825,-0.439912661259074,0.4821074349746622,1.0505819654024655,0.14666752913432865,0.002434827265685641,3.475941491201594,2.8008425897497315,-0.6583020446262418,-0.030206765888258928,0.5841039652256301,0.5984987511004508,0.2713647192914942,0.6271586509706826,-1.065173276993352
3,069
oxidoreductase
16
44
2.599935
0.009324
Q9Y6M9,P16435,O96000,O43676,O14949,O15254,O43396,P00403,Q8N0U8,P03915,O43169,Q86Y39,Q8N4Q0,Q15067,O75306,Q96HE7
Functions
Panther Protein class
panther_protein_class
161,351,225,38,70,263,268,108,112,242,19,179,118,409,437,251
679,1218,70,263,19,268,1945,38,1288,437,2312,590,564,225,108,242,2838,776,2097,351,2794,1805,2698,2169,2866,2797,1434,958,1439,409,934,881,2519,2752,1134,179,112,118,3033,251,2851,1331,461,161
0.43772031258177796,0.002434827265685641,2.7380995161851818,1.317199369207603,3.506338746109396,1.304842448283804,-0.3692094267674327,3.143192229979514,-0.030206765888258928,0.7955852218137351,-0.5661333020712928,0.5551835148202413,0.5841039652256301,1.4987164375383368,2.3319722280450734,1.4269590798007796,-0.9652573139184435,0.3476949375688096,-0.439912661259074,1.0243805753397968,-0.9062487336772611,-0.2995072265011157,-0.8094210498506128,-0.4756480043806108,-1.0049855843887756,-0.9062487336772611,-0.11278048268758513,0.19380682512269046,-0.11278048268758513,0.8504247102515363,0.2094183652836215,0.255952511861343,-0.6769429135129599,-0.847927384389837,0.06706796620069248,1.7862524375899929,2.2521766001450425,2.2218852461661323,-1.7329818849185776,1.390659754720825,-0.9652573139184435,-0.04660999391817365,0.7679256085196353,1.8745887034572348
3,069
Side of membrane
22
69
2.599449
0.009337
P07237,Q9H0H5,P41440,P62942,O96005,P10619,O15439,P08183,Q9Y5X3,P55899,Q9NR28,P02786,P09471,P10321,P42892,P51790,Q9UBI6,P00813,Q8TCT9,P17900,P11279,P51572
Localization
GO Cellular component
msigdb_gocc
512,515,269,392,144,20,278,152,549,157,170,181,315,323,68,329,470,492,113,117,374,377
1121,949,278,551,144,1771,492,1127,181,599,703,1221,1128,512,1055,152,1911,315,323,20,2791,374,1197,966,2677,2379,2131,117,777,683,820,850,2745,1222,758,1199,1843,2167,269,68,1809,1776,377,329,157,2542,1148,392,2748,1149,2905,1183,2424,1299,634,1707,1788,973,113,1797,2241,2012,1214,515,170,470,1760,2467,549
0.06706796620069248,0.19380682512269046,1.2550845585859318,0.6128502332132403,1.9612496555436207,-0.28223504260053384,0.7121179729480956,0.06706796620069248,1.7750896222834918,0.5406573616707142,0.4078989792455411,0.002434827265685641,0.06706796620069248,0.669827883440752,0.11498437510700303,1.9072797273295248,-0.3516910545716578,1.1283203698531714,1.11545308586704,3.506338746109396,-0.9062487336772611,0.931509813270278,0.018673868634717674,0.17814470796339205,-0.79027866305354,-0.6027955681655673,-0.45774800066276633,2.2218852461661323,0.3476949375688096,0.43772031258177796,0.30204211533490194,0.2713647192914942,-0.847927384389837,0.002434827265685641,0.36281679569392605,0.018673868634717674,-0.3168403575565848,-0.4756480043806108,1.304842448283804,2.7561169853489744,-0.2995072265011157,-0.28223504260053384,0.931509813270278,1.0766380800365236,1.8855117311614753,-0.6956539386154175,0.05099010895251097,0.8911412130144085,-0.847927384389837,0.05099010895251097,-1.0853969322237222,0.0348588523240148,-0.6212288478544631,-0.030206765888258928,0.4968122165583206,-0.24787194526949927,-0.28223504260053384,0.17814470796339205,2.2521766001450425,-0.28223504260053384,-0.511643742111834,-0.3867903586863053,0.018673868634717674,0.669827883440752,1.8306337022721588,0.7540350803801485,-0.26502341218255865,-0.6397308488356486,0.6271586509706826
3,069
Proton transmembrane transporter activity
12
36
2.591461
0.009557
Q96ES6,Q93050,P13073,P24539,Q7KZN9,P12235,P00846,P51790,P00403,Q9Y487,Q9UDW1,O75964
Functions
GO Molecular function
msigdb_gomf
33,163,538,448,331,553,42,329,108,562,57,93
700,1520,93,591,108,42,1054,908,910,1167,553,538,778,1365,2743,448,1956,1315,928,1078,2678,969,2865,329,1059,840,1180,913,1208,331,163,33,57,1939,562,752
0.4078989792455411,-0.16300366701431568,2.449071204722446,0.5551835148202413,2.3319722280450734,3.034827813634531,0.11498437510700303,0.22497962854566572,0.22497962854566572,0.0348588523240148,0.6128502332132403,0.6271586509706826,0.3476949375688096,-0.07958302654545266,-0.847927384389837,0.781775583130449,-0.3692094267674327,-0.04660999391817365,0.2094183652836215,0.09906477879078189,-0.79027866305354,0.17814470796339205,-1.0049855843887756,1.0766380800365236,0.11498437510700303,0.2867278246330759,0.0348588523240148,0.22497962854566572,0.018673868634717674,1.0766380800365236,1.863639502869007,3.2328322525717677,2.8451205119843253,-0.3516910545716578,0.5984987511004508,0.37789124027862775
3,069
Steroid metabolic process
18
62
2.586697
0.00969
Q15392,Q15800,O95470,P16435,P37268,Q13510,P34913,Q14534,P38435,P04062,Q8WTV0,Q9H4L5,Q9UBM7,Q16850,P05023,P30536,O15118,P38571
Processes and pathways
GO Biological process
msigdb_gobp
96,97,194,351,232,139,362,301,174,45,16,237,366,243,404,53,91,221
690,526,91,989,1602,194,1909,45,404,2675,1197,991,2412,351,1145,1636,2794,2320,836,53,362,600,232,174,221,2100,407,874,2383,1261,2511,3017,2232,1612,1403,139,2577,301,614,1678,96,2707,2550,1378,97,243,695,1750,829,16,2397,2180,2851,675,1092,631,237,366,2976,749,2635,1385
0.4228328131433475,0.6414242418555797,2.449071204722446,0.16243171108876198,-0.1967746802526644,1.6619426173233864,-0.3516910545716578,3.017915919263261,0.8640358745112992,-0.79027866305354,0.018673868634717674,0.16243171108876198,-0.6212288478544631,1.0243805753397968,0.05099010895251097,-0.21374796024844483,-0.9062487336772611,-0.5661333020712928,0.2867278246330759,2.915054362320261,0.97153594878527,0.5406573616707142,1.462976639584121,1.8084968281201592,1.5223905970530132,-0.439912661259074,0.8504247102515363,0.255952511861343,-0.6027955681655673,-0.013858605375158513,-0.6769429135129599,-1.5299171060170624,-0.511643742111834,-0.1967746802526644,-0.09615352598164383,1.9933274484979564,-0.7144356079504978,1.1794390031101867,0.5260869274788118,-0.23078025553282336,2.4297657388802323,-0.8094210498506128,-0.6956539386154175,-0.07958302654545266,2.4200817299635164,1.414890812147365,0.4228328131433475,-0.26502341218255865,0.30204211533490194,3.544036436727491,-0.6027955681655673,-0.4756480043806108,-0.9652573139184435,0.45256174173642805,0.09906477879078189,0.5114719629049498,1.4510018447343276,0.9582316246880604,-1.271153586891543,0.37789124027862775,-0.7522128562660492,-0.07958302654545266
3,069
Protein transmembrane import into intracellular organelle
7
13
2.579812
0.009885
O60830,Q99595,Q3ZCQ8,O75381,O96008,O14925,Q8N4Q1
Processes and pathways
GO Biological process
msigdb_gobp
0,3,541,361,399,146,412
146,1096,0,361,757,564,399,2162,541,412,3,1136,948
1.950506657749701,0.08309274884485632,4.125669255470878,0.97153594878527,0.36281679569392605,0.5841039652256301,0.8776079734066499,-0.4756480043806108,0.6271586509706826,0.836774272954116,4.125669255470878,0.06706796620069248,0.2094183652836215
3,069
Sphingolipid metabolism integrated pathway
6
9
2.578393
0.009926
O95470,Q06136,P27544,Q13510,O15121,Q96G23
Processes and pathways
WikiPathways
msigdb_wp
194,167,106,139,205,86
205,383,1601,194,106,167,139,808,86
1.5926941854384824,0.9180919307885846,-0.1967746802526644,1.6619426173233864,2.341847947069304,1.8526640136185266,1.9933274484979564,0.3173078764001649,2.5064930869004933
3,069
Sphingolipid metabolism overview
6
9
2.578393
0.009926
O95470,Q06136,P27544,Q13510,O15121,Q96G23
Processes and pathways
WikiPathways
msigdb_wp
194,167,106,139,205,86
205,383,1601,194,106,167,139,808,86
1.5926941854384824,0.9180919307885846,-0.1967746802526644,1.6619426173233864,2.341847947069304,1.8526640136185266,1.9933274484979564,0.3173078764001649,2.5064930869004933
3,069
Nucleotide transport
10
14
2.574254
0.010046
Q9HC21,Q8TDW0,P12235,P41440,O00400,Q8TB61,O15439,Q6NUK1,Q08722,P12236
Processes and pathways
GO Biological process
msigdb_gobp
488,522,553,269,700,83,278,441,347,565
700,278,950,1054,553,565,269,347,441,898,83,522,731,488
0.4078989792455411,1.2550845585859318,0.19380682512269046,0.11498437510700303,0.6128502332132403,0.5841039652256301,1.304842448283804,1.0374995229846102,0.7955852218137351,0.2404909124205327,2.525471026963564,0.655647241447091,0.39291854449948976,0.7261314845184232
3,069
Metabolism of lipids
52
170
2.566612
0.01027
P51648,O15269,Q8NCC3,Q13510,O15254,P50897,P10619,Q15067,Q15165,Q8NF37,Q96N66,Q9UKU0,Q9NPH0,P23786,Q06136,P06280,O43681,P04062,Q9UMR5,P38435,P07602,Q9NUQ2,Q10713,Q14534,Q9H7Z7,P30536,Q8IVS2,Q9NZ01,O95470,Q9UG56,P16278,P06865,O95772,O15121,Q96G23,O00116,Q15392,Q15800,Q8IV08,P37268,P27544,P16219,P34913,Q9H4L5,Q9UBM7,Q9P035,Q16850,O43772,P17900,Q9BY49,P48651,Q9NZJ7
Processes and pathways
Reactome Pathways
msigdb_reactome
128,383,135,139,263,13,20,409,153,154,155,282,30,166,167,295,298,45,46,174,48,176,177,301,305,53,311,63,194,69,203,328,80,205,86,218,96,97,99,232,106,235,362,237,366,240,243,116,117,121,375,256
1121,218,2090,2588,434,3067,690,2970,526,205,818,263,383,1601,298,116,950,2589,2277,1487,719,702,1633,2536,1634,194,2314,1948,1014,80,1219,45,3066,953,295,328,48,775,2675,1074,20,682,991,2412,2954,235,203,2793,2742,117,2872,1736,820,1605,1145,1636,2794,166,2320,106,2507,53,692,362,600,2351,232,174,1319,891,2100,892,2866,407,375,1058,1776,874,970,13,128,1261,1262,2511,2476,2451,3017,1038,1780,1643,823,1612,167,177,3064,139,1438,2577,301,614,3040,2146,409,1678,153,1787,96,1267,2550,1378,97,560,243,808,2856,1679,695,827,764,1618,1086,1577,2006,99,311,2486,3033,2110,1793,2552,829,135,154,884,997,630,86,155,2269,2180,2304,2338,1349,2012,797,1025,2713,121,2937,237,305,2529,30,1900,557,176,986,63,622,256,240,1307,366,69,282,46,1830,1386,1557,1558
0.06706796620069248,1.5341823947732471,-0.439912661259074,-0.7332884144977851,0.7955852218137351,-8.86661206184794,0.4228328131433475,-1.271153586891543,0.6414242418555797,1.5926941854384824,0.30204211533490194,1.317199369207603,0.9180919307885846,-0.1967746802526644,1.1794390031101867,2.2218852461661323,0.19380682512269046,-0.7332884144977851,-0.5479033919239744,-0.14620519285903205,0.39291854449948976,0.4078989792455411,-0.21374796024844483,-0.6956539386154175,-0.21374796024844483,1.6619426173233864,-0.5661333020712928,-0.3692094267674327,0.14666752913432865,2.572565986061649,0.002434827265685641,3.017915919263261,-8.108514716671277,0.19380682512269046,1.1921319124623524,1.0766380800365236,2.9924252844164885,0.3476949375688096,-0.79027866305354,0.09906477879078189,3.506338746109396,0.43772031258177796,0.16243171108876198,-0.6212288478544631,-1.2292802103878024,1.4510018447343276,1.6043080729323946,-0.9062487336772611,-0.847927384389837,2.2218852461661323,-1.0249681947485962,-0.26502341218255865,0.30204211533490194,-0.1967746802526644,0.05099010895251097,-0.21374796024844483,-0.9062487336772611,1.8526640136185266,-0.5661333020712928,2.341847947069304,-0.6769429135129599,2.915054362320261,0.4228328131433475,0.97153594878527,0.5406573616707142,-0.5844305409591135,1.462976639584121,1.8084968281201592,-0.04660999391817365,0.2404909124205327,-0.439912661259074,0.2404909124205327,-1.0049855843887756,0.8504247102515363,0.931509813270278,0.11498437510700303,-0.28223504260053384,0.255952511861343,0.17814470796339205,3.6110714012320395,2.056812333710736,-0.013858605375158513,-0.013858605375158513,-0.6769429135129599,-0.6583020446262418,-0.6397308488356486,-1.5299171060170624,0.13085185405757133,-0.28223504260053384,-0.21374796024844483,0.30204211533490194,-0.1967746802526644,1.8526640136185266,1.7862524375899929,-7.8290380042455,1.9933274484979564,-0.11278048268758513,-0.7144356079504978,1.1794390031101867,0.5260869274788118,-1.8729618416459095,-0.45774800066276633,0.8504247102515363,-0.23078025553282336,1.9072797273295248,-0.28223504260053384,2.4297657388802323,-0.013858605375158513,-0.6956539386154175,-0.07958302654545266,2.4200817299635164,0.5984987511004508,1.414890812147365,0.3173078764001649,-0.9850821494668925,-0.23078025553282336,0.4228328131433475,0.30204211533490194,0.36281679569392605,-0.1967746802526644,0.09906477879078189,-0.17986003989876528,-0.3867903586863053,2.3811352391695215,1.1411524269414506,-0.6583020446262418,-1.7329818849185776,-0.439912661259074,-0.28223504260053384,-0.6956539386154175,0.30204211533490194,2.025180715051222,1.9072797273295248,0.255952511861343,0.16243171108876198,0.5114719629049498,2.5064930869004933,1.9072797273295248,-0.529740355465412,-0.4756480043806108,-0.5479033919239744,-0.5661333020712928,-0.06306863218986276,-0.3867903586863053,0.33252539041368356,0.14666752913432865,-0.8094210498506128,2.1606861561903865,-1.1671130876239315,1.4510018447343276,1.1539494344082741,-0.6769429135129599,3.256962955946114,-0.3342348331799229,0.6128502332132403,1.8084968281201592,0.17814470796339205,2.78300653577057,0.5260869274788118,1.3784966610797764,1.4389960408956042,-0.030206765888258928,0.9582316246880604,2.7561169853489744,1.2550845585859318,3.017915919263261,-0.2995072265011157,-0.07958302654545266,-0.16300366701431568,-0.16300366701431568
3,069
Glycerolipid biosynthetic process
7
37
2.564038
0.010346
Q9UG56,Q8NCC3,Q8WTV0,Q9NUQ2,Q8NF37,Q96N66,Q9NPH0
Processes and pathways
GO Biological process
msigdb_gobp
69,135,16,176,154,155,30
2588,434,2970,818,1053,1255,1948,1014,2953,2131,692,375,177,1438,1854,1618,1086,135,154,884,16,997,630,1538,2010,155,1412,2304,1349,797,1510,768,30,557,176,2248,69
-0.7332884144977851,0.7955852218137351,-1.271153586891543,0.30204211533490194,0.11498437510700303,-0.013858605375158513,-0.3692094267674327,0.14666752913432865,-1.2292802103878024,-0.45774800066276633,0.4228328131433475,0.931509813270278,1.7862524375899929,-0.11278048268758513,-0.3168403575565848,-0.1967746802526644,0.09906477879078189,2.025180715051222,1.9072797273295248,0.255952511861343,3.544036436727491,0.16243171108876198,0.5114719629049498,-0.16300366701431568,-0.3867903586863053,1.9072797273295248,-0.09615352598164383,-0.5479033919239744,-0.06306863218986276,0.33252539041368356,-0.14620519285903205,0.36281679569392605,3.256962955946114,0.6128502332132403,1.8084968281201592,-0.511643742111834,2.7561169853489744
3,069
Serine hydrolase activity
6
17
2.560757
0.010444
O14773,Q9HB40,Q9H3G5,P10619,P42785,Q16740
Functions
GO Molecular function
msigdb_gomf
67,7,297,20,22,62
67,589,20,1735,2448,2168,22,2796,1178,2259,309,62,625,431,628,297,7
2.7650983212483924,0.5551835148202413,3.506338746109396,-0.26502341218255865,-0.6397308488356486,-0.4756480043806108,3.4835609026263072,-0.9062487336772611,0.0348588523240148,-0.529740355465412,1.1411524269414506,2.78300653577057,0.5114719629049498,0.8093547404733235,0.5114719629049498,1.1921319124623524,3.841271916977857
3,069
Sterol metabolic process
12
32
2.559018
0.010497
Q15392,Q15800,P16435,P37268,P34913,P04062,Q14534,Q9UBM7,Q8WTV0,Q16850,O15118,P38571
Processes and pathways
GO Biological process
msigdb_gobp
96,97,351,232,362,45,301,366,16,243,91,221
91,989,1602,1909,45,1197,991,351,2794,362,600,232,221,2100,407,874,2511,3017,2232,1612,2577,301,614,1678,96,1378,97,243,16,366,2976,2635
2.449071204722446,0.16243171108876198,-0.1967746802526644,-0.3516910545716578,3.017915919263261,0.018673868634717674,0.16243171108876198,1.0243805753397968,-0.9062487336772611,0.97153594878527,0.5406573616707142,1.462976639584121,1.5223905970530132,-0.439912661259074,0.8504247102515363,0.255952511861343,-0.6769429135129599,-1.5299171060170624,-0.511643742111834,-0.1967746802526644,-0.7144356079504978,1.1794390031101867,0.5260869274788118,-0.23078025553282336,2.4297657388802323,-0.07958302654545266,2.4200817299635164,1.414890812147365,3.544036436727491,0.9582316246880604,-1.271153586891543,-0.7522128562660492
3,069
Cherry red spot of the macula
6
9
2.556844
0.010563
Q13510,P16278,P07602,P10619,P17900,Q9NZJ7
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
139,203,48,20,117,256
328,48,775,20,2378,203,117,139,256
1.0766380800365236,2.9924252844164885,0.3476949375688096,3.506338746109396,-0.6027955681655673,1.6043080729323946,2.2218852461661323,1.9933274484979564,1.3784966610797764
3,069
Skin nodule
8
19
2.555496
0.010604
Q9NSE4,P06280,Q13510,P34913,P11802,P35637,P16615,P21912
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
489,295,139,362,426,280,249,158
1126,1127,295,426,249,158,804,362,1916,280,1080,1776,504,2798,139,1347,489,1031,1252
0.06706796620069248,0.06706796620069248,1.1921319124623524,0.8093547404733235,1.390659754720825,1.8745887034572348,0.3173078764001649,0.97153594878527,-0.3516910545716578,1.2550845585859318,0.09906477879078189,-0.28223504260053384,0.6839663996681922,-0.9062487336772611,1.9933274484979564,-0.06306863218986276,0.7261314845184232,0.14666752913432865,0.002434827265685641
3,069
transmembrane signal receptor
6
7
2.55189
0.010714
Q9UMX5,Q99720,O15173,Q8WUJ1,O00264,Q96GC9
Functions
Panther Protein class
panther_protein_class
72,107,109,54,214,124
214,109,338,54,124,107,72
1.5576761325356283,2.3220747758671,1.0505819654024655,2.906373043866094,2.129773251435637,2.341847947069304,2.7290632457691744
3,069
Peptidase activity
20
106
2.551397
0.010729
Q9HB40,Q969V3,Q96RU2,P10619,P42785,Q99797,Q9H3G5,P28072,Q10713,P02786,P28070,Q16740,P53582,O14773,P42892,O75844,P49721,P55786,Q9UIQ6,Q8TCT9
Functions
GO Molecular function
msigdb_gomf
7,9,270,20,22,286,297,171,177,181,191,62,192,67,68,73,74,76,100,113
1390,2187,67,1123,1053,1124,1428,73,589,1837,2190,181,2723,1074,20,3026,1735,966,2131,647,668,2321,191,171,610,2997,2448,1668,759,2168,22,68,2030,2796,418,74,1740,1473,1100,1178,192,2259,2229,76,527,1741,309,3055,177,2387,2575,3027,2204,506,62,625,2684,431,937,843,2042,2972,2331,856,628,1408,899,113,629,1717,1584,1346,2712,1718,9,2151,2366,941,458,2398,270,1798,532,1091,2782,286,2338,452,2117,297,2609,1281,1118,7,748,1865,1190,2052,2634,2156,1031,1417,100,750,865,1485
-0.09615352598164383,-0.4936131056899879,2.7650983212483924,0.06706796620069248,0.11498437510700303,0.06706796620069248,-0.11278048268758513,2.71093528756688,0.5551835148202413,-0.3168403575565848,-0.4936131056899879,1.7750896222834918,-0.828637115565359,0.09906477879078189,3.506338746109396,-1.6417356749509124,-0.26502341218255865,0.17814470796339205,-0.45774800066276633,0.4821074349746622,0.45256174173642805,-0.5661333020712928,1.6961801986761367,1.8195786448550066,0.5260869274788118,-1.3773759425498497,-0.6397308488356486,-0.23078025553282336,0.36281679569392605,-0.4756480043806108,3.4835609026263072,2.7561169853489744,-0.404434263179806,-0.9062487336772611,0.8230843533330983,2.6927329741593415,-0.26502341218255865,-0.1294642520833557,0.08309274884485632,0.0348588523240148,1.6733834780213133,-0.529740355465412,-0.511643742111834,2.6376742328100615,0.6414242418555797,-0.26502341218255865,1.1411524269414506,-2.7185293015717313,1.7862524375899929,-0.6027955681655673,-0.7144356079504978,-1.6417356749509124,-0.4936131056899879,0.6839663996681922,2.78300653577057,0.5114719629049498,-0.79027866305354,0.8093547404733235,0.2094183652836215,0.2867278246330759,-0.404434263179806,-1.271153586891543,-0.5661333020712928,0.2713647192914942,0.5114719629049498,-0.09615352598164383,0.2404909124205327,2.2521766001450425,0.5114719629049498,-0.24787194526949927,-0.17986003989876528,-0.06306863218986276,-0.8094210498506128,-0.24787194526949927,3.777771015939243,-0.45774800066276633,-0.5844305409591135,0.2094183652836215,0.7679256085196353,-0.6027955681655673,1.304842448283804,-0.28223504260053384,0.6414242418555797,0.09906477879078189,-0.8867326554727312,1.242561719212632,-0.5661333020712928,0.781775583130449,-0.439912661259074,1.1921319124623524,-0.7332884144977851,-0.013858605375158513,0.08309274884485632,3.841271916977857,0.37789124027862775,-0.3168403575565848,0.0348588523240148,-0.404434263179806,-0.7522128562660492,-0.45774800066276633,0.14666752913432865,-0.09615352598164383,2.3713455802707064,0.37789124027862775,0.2713647192914942,-0.1294642520833557
3,069
Microbody
22
57
2.550861
0.010746
P51648,O15254,Q9NR77,P56589,Q15067,O14975,Q9UKU0,Q9NQG6,Q9GZY8,Q9BTZ2,Q13011,P39210,P33121,P40855,Q8TB36,O00116,P08670,P34913,O75381,Q6YN16,Q8N4Q0,Q9BY49
Localization
GO Cellular component
msigdb_gocc
128,263,12,273,409,526,282,677,544,675,159,300,692,316,604,218,226,362,361,627,118,121
218,1422,690,526,818,263,950,2277,361,1633,1126,1948,226,2675,1493,966,1636,836,2900,2698,692,362,2351,2167,300,316,1080,128,1261,273,159,2577,409,1678,764,1618,627,1577,1234,118,996,604,997,1448,1506,1861,1049,675,121,544,677,12,1689,282,1982,2563,948
1.5341823947732471,-0.11278048268758513,0.4228328131433475,0.6414242418555797,0.30204211533490194,1.317199369207603,0.19380682512269046,-0.5479033919239744,0.97153594878527,-0.21374796024844483,0.06706796620069248,-0.3692094267674327,1.4987164375383368,-0.79027866305354,-0.14620519285903205,0.17814470796339205,-0.21374796024844483,0.2867278246330759,-1.0853969322237222,-0.8094210498506128,0.4228328131433475,0.97153594878527,-0.5844305409591135,-0.4756480043806108,1.1794390031101867,1.1283203698531714,0.09906477879078189,2.056812333710736,-0.013858605375158513,1.280029869062608,1.8745887034572348,-0.7144356079504978,0.8504247102515363,-0.23078025553282336,0.36281679569392605,-0.1967746802526644,0.5114719629049498,-0.17986003989876528,0.002434827265685641,2.2218852461661323,0.16243171108876198,0.5406573616707142,0.16243171108876198,-0.11278048268758513,-0.14620519285903205,-0.3168403575565848,0.13085185405757133,0.45256174173642805,2.1606861561903865,0.6271586509706826,0.45256174173642805,3.6331860602374753,-0.23078025553282336,1.2550845585859318,-0.3692094267674327,-0.6956539386154175,0.2094183652836215
3,069
Oxidative phosphorylation
13
59
2.549306
0.010794
Q9Y6M9,O96000,P14406,O43676,O14949,Q7KZN9,P00846,Q9H3K2,P00403,P03915,Q9UDW1,O75306,O75964
Processes and pathways
GO Biological process
msigdb_gobp
161,225,1,38,70,331,42,397,108,242,57,437,93
679,1218,70,1945,38,1288,1836,437,2312,1429,1520,93,590,1947,225,108,42,242,872,908,910,776,1167,538,1,2502,1198,2098,2132,778,668,448,1956,2899,2137,1606,1315,1841,928,1525,969,2865,2797,1434,1263,1059,840,881,2519,809,331,2606,2782,861,397,57,1309,717,161
0.43772031258177796,0.002434827265685641,2.7380995161851818,-0.3692094267674327,3.143192229979514,-0.030206765888258928,-0.3168403575565848,0.7955852218137351,-0.5661333020712928,-0.11278048268758513,-0.16300366701431568,2.449071204722446,0.5551835148202413,-0.3692094267674327,1.4987164375383368,2.3319722280450734,3.034827813634531,1.4269590798007796,0.255952511861343,0.22497962854566572,0.22497962854566572,0.3476949375688096,0.0348588523240148,0.6271586509706826,4.125669255470878,-0.6769429135129599,0.018673868634717674,-0.439912661259074,-0.45774800066276633,0.3476949375688096,0.45256174173642805,0.781775583130449,-0.3692094267674327,-1.0853969322237222,-0.45774800066276633,-0.1967746802526644,-0.04660999391817365,-0.3168403575565848,0.2094183652836215,-0.16300366701431568,0.17814470796339205,-1.0049855843887756,-0.9062487336772611,-0.11278048268758513,-0.013858605375158513,0.11498437510700303,0.2867278246330759,0.255952511861343,-0.6769429135129599,0.3173078764001649,1.0766380800365236,-0.7332884144977851,-0.8867326554727312,0.2713647192914942,0.8911412130144085,2.8451205119843253,-0.030206765888258928,0.4078989792455411,1.8745887034572348
3,069
Postural tremor
7
18
2.547526
0.010849
O14773,Q14108,P00846,Q9NR77,P03915,P35637,Q9H6K4
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
67,37,42,12,242,280,89
67,2127,437,597,835,1634,42,242,967,280,330,3014,37,2782,89,606,12,1385
2.7650983212483924,-0.45774800066276633,0.7955852218137351,0.5406573616707142,0.2867278246330759,-0.21374796024844483,3.034827813634531,1.4269590798007796,0.17814470796339205,1.2550845585859318,1.0766380800365236,-1.5078440030591196,3.176002075643978,-0.8867326554727312,2.4874342296963574,0.5406573616707142,3.6331860602374753,-0.07958302654545266
3,069
Abnormal peripheral nervous system physiology
18
50
2.544665
0.010938
O15269,Q9Y619,Q9UBB4,O43681,Q99720,Q9NR77,Q8N2K0,P39210,P04792,Q9Y3E5,P07602,O15121,Q8TB36,O60220,P07196,Q9NZJ7,Q9GZY8,O95831
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
383,131,459,298,107,12,393,300,592,535,48,205,604,335,215,256,544,564
205,383,1601,298,335,2887,802,835,871,564,598,592,215,48,1258,1635,967,1315,300,2475,1202,1367,2449,1433,1739,1261,1263,2778,3008,1614,1438,960,1968,1677,2206,393,604,2487,900,2490,107,544,1452,12,256,2403,459,535,131,1558
1.5926941854384824,0.9180919307885846,-0.1967746802526644,1.1794390031101867,1.0505819654024655,-1.065173276993352,0.3173078764001649,0.2867278246330759,0.255952511861343,0.5841039652256301,0.5406573616707142,0.5551835148202413,1.5576761325356283,2.9924252844164885,-0.013858605375158513,-0.21374796024844483,0.17814470796339205,-0.04660999391817365,1.1794390031101867,-0.6583020446262418,0.018673868634717674,-0.07958302654545266,-0.6397308488356486,-0.11278048268758513,-0.26502341218255865,-0.013858605375158513,-0.013858605375158513,-0.8867326554727312,-1.4421921442388042,-0.1967746802526644,-0.11278048268758513,0.19380682512269046,-0.3692094267674327,-0.23078025553282336,-0.4936131056899879,0.8911412130144085,0.5406573616707142,-0.6583020446262418,0.2404909124205327,-0.6583020446262418,2.341847947069304,0.6271586509706826,-0.11278048268758513,3.6331860602374753,1.3784966610797764,-0.6027955681655673,0.7679256085196353,0.6414242418555797,2.0462929128969036,-0.16300366701431568
3,069
Amyloid beta binding
6
11
2.542046
0.011021
Q9UHV9,P61758,Q8WTV0,Q07954,Q9NQX7,O00264
Functions
GO Molecular function
msigdb_gomf
424,292,16,371,150,214
214,537,1960,292,371,1375,16,1540,1138,150,424
1.5576761325356283,0.6271586509706826,-0.3692094267674327,1.2047904684516537,0.9448896451261036,-0.07958302654545266,3.544036436727491,-0.16300366701431568,0.06706796620069248,1.928944402879871,0.8230843533330983
3,069
Ectrodactyly
7
14
2.539707
0.011095
Q99720,Q9NR77,P04792,Q9UBM7,O95202,P07196,P48449
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
107,12,592,366,591,215,407
591,1464,592,215,407,1261,2600,1134,604,107,1351,12,366,1558
0.5551835148202413,-0.1294642520833557,0.5551835148202413,1.5576761325356283,0.8504247102515363,-0.013858605375158513,-0.7332884144977851,0.06706796620069248,0.5406573616707142,2.341847947069304,-0.06306863218986276,3.6331860602374753,0.9582316246880604,-0.16300366701431568
3,069
Glycosidase
7
18
2.539602
0.011098
P06280,P16278,P04062,P10253,Q9BTY2,O60502,P54802
Functions
Protein Atlas Molecular function
protein_atlas_molecular_function
295,203,45,85,186,156,222
1559,1164,156,45,658,295,328,775,454,85,203,2509,222,623,960,2293,2262,186
-0.17986003989876528,0.0348588523240148,1.8855117311614753,3.017915919263261,0.4673573625937165,1.1921319124623524,1.0766380800365236,0.3476949375688096,0.7679256085196353,2.5064930869004933,1.6043080729323946,-0.6769429135129599,1.5223905970530132,0.5114719629049498,0.19380682512269046,-0.5479033919239744,-0.529740355465412,1.7414372304609023
3,069
Lipid binding
26
131
2.530744
0.011382
P45880,Q8NCC3,O15254,Q8TEU7,P50897,P21796,Q8WTV0,P56589,P05023,Q14108,P04062,P38435,P07602,P30536,P28070,O14773,Q99623,O95772,O00264,P20073,O15118,A6NIH7,Q9H4L5,O15173,P50995,Q9NZJ7
Functions
GO Molecular function
msigdb_gomf
8,135,263,394,13,15,16,273,404,37,45,174,48,53,191,67,333,80,214,336,91,98,237,109,376,256
1121,1072,98,214,949,1422,2588,2970,67,1033,2871,91,109,263,2498,1053,2253,802,1357,869,719,989,756,1602,2943,927,80,45,599,1194,404,1195,48,2023,1055,721,2282,498,2162,2791,1491,2839,722,2195,336,1912,15,1145,1636,2222,191,2136,2761,1497,53,439,600,2286,174,8,2596,1809,1058,13,376,1569,894,1225,1263,3045,273,1742,2232,1745,878,1747,1103,1375,1376,2818,37,2236,2800,409,2599,2294,764,2041,1480,3032,135,485,394,1304,16,1381,605,2241,2431,2335,2180,885,333,2338,1188,2582,2012,2493,2937,515,768,237,487,2529,3000,256,987,2870,1309,1759,1161,2404,800,1051,2667,1120,2638,1421,2467,549,2587
0.06706796620069248,0.09906477879078189,2.41037675952631,1.5576761325356283,0.19380682512269046,-0.11278048268758513,-0.7332884144977851,-1.271153586891543,2.7650983212483924,0.13085185405757133,-1.0249681947485962,2.449071204722446,2.3220747758671,1.317199369207603,-0.6769429135129599,0.11498437510700303,-0.529740355465412,0.3173078764001649,-0.07958302654545266,0.255952511861343,0.39291854449948976,0.16243171108876198,0.36281679569392605,-0.1967746802526644,-1.2084727595847877,0.2094183652836215,2.572565986061649,3.017915919263261,0.5406573616707142,0.018673868634717674,0.8640358745112992,0.018673868634717674,2.9924252844164885,-0.404434263179806,0.11498437510700303,0.39291854449948976,-0.5479033919239744,0.6980630201166272,-0.4756480043806108,-0.9062487336772611,-0.14620519285903205,-0.9652573139184435,0.39291854449948976,-0.4936131056899879,1.0505819654024655,-0.3516910545716578,3.551536551149184,0.05099010895251097,-0.21374796024844483,-0.511643742111834,1.6961801986761367,-0.45774800066276633,-0.8672923859684633,-0.14620519285903205,2.915054362320261,0.7955852218137351,0.5406573616707142,-0.5479033919239744,1.8084968281201592,3.7990432016623545,-0.7332884144977851,-0.2995072265011157,0.11498437510700303,3.6110714012320395,0.931509813270278,-0.17986003989876528,0.2404909124205327,0.002434827265685641,-0.013858605375158513,-2.1150366043388837,1.280029869062608,-0.26502341218255865,-0.511643742111834,-0.26502341218255865,0.255952511861343,-0.26502341218255865,0.08309274884485632,-0.07958302654545266,-0.07958302654545266,-0.9258411670371093,3.176002075643978,-0.511643742111834,-0.9062487336772611,0.8504247102515363,-0.7332884144977851,-0.5479033919239744,0.36281679569392605,-0.404434263179806,-0.1294642520833557,-1.7329818849185776,2.025180715051222,0.7261314845184232,0.8911412130144085,-0.030206765888258928,3.544036436727491,-0.07958302654545266,0.5406573616707142,-0.511643742111834,-0.6212288478544631,-0.5661333020712928,-0.4756480043806108,0.255952511861343,1.0636280893102765,-0.5661333020712928,0.0348588523240148,-0.7144356079504978,-0.3867903586863053,-0.6583020446262418,-1.1671130876239315,0.669827883440752,0.36281679569392605,1.4510018447343276,0.7261314845184232,-0.6769429135129599,-1.3773759425498497,1.3784966610797764,0.17814470796339205,-1.0049855843887756,-0.030206765888258928,-0.26502341218255865,0.05099010895251097,-0.6027955681655673,0.33252539041368356,0.13085185405757133,-0.7712094363609074,0.08309274884485632,-0.7522128562660492,-0.09615352598164383,-0.6397308488356486,0.6271586509706826,-0.7144356079504978
3,069
Mitochondrial calcium ion transmembrane transport
6
11
2.525246
0.011562
Q96AQ8,P21796,Q9BPX6,Q8WWC4,Q9H4I9,Q8IYU8
Processes and pathways
GO Biological process
msigdb_gobp
514,15,343,210,24,384
1428,591,15,384,1580,210,514,343,24,1309,865
-0.11278048268758513,0.5551835148202413,3.551536551149184,0.9180919307885846,-0.17986003989876528,1.5693783522525775,0.669827883440752,1.0505819654024655,3.475941491201594,-0.030206765888258928,0.2713647192914942
3,069
Abnormality of corneal stroma
6
11
2.521195
0.011696
Q16625,P54886,Q13510,P04062,P16278,P10619
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
227,330,139,45,203,20
559,45,20,203,1056,1635,362,330,2876,139,227
0.5984987511004508,3.017915919263261,3.506338746109396,1.6043080729323946,0.11498437510700303,-0.21374796024844483,0.97153594878527,1.0766380800365236,-1.0249681947485962,1.9933274484979564,1.4987164375383368
3,069
Myoclonic seizure
12
53
2.519563
0.01175
Q9Y619,P00846,Q13510,P16278,P04062,P07602,Q01105,P03915,Q5XKP0,O75503,Q96N66,P21912
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
131,42,139,203,45,48,81,242,244,58,155,158
2717,1422,2373,718,1053,2534,951,1255,58,1769,42,242,45,48,775,3051,203,158,1606,1878,2702,1175,2383,1608,1147,823,2512,81,2945,2905,1183,1614,139,1968,2482,244,742,3032,1447,1538,2334,2431,2335,155,606,256,2692,2439,509,1555,535,865,131
-0.828637115565359,-0.11278048268758513,-0.6027955681655673,0.39291854449948976,0.11498437510700303,-0.6956539386154175,0.19380682512269046,-0.013858605375158513,2.8363003459677576,-0.28223504260053384,3.034827813634531,1.4269590798007796,3.017915919263261,2.9924252844164885,0.3476949375688096,-2.421230489514741,1.6043080729323946,1.8745887034572348,-0.1967746802526644,-0.3342348331799229,-0.8094210498506128,0.0348588523240148,-0.6027955681655673,-0.1967746802526644,0.05099010895251097,0.30204211533490194,-0.6769429135129599,2.563186671331025,-1.2084727595847877,-1.0853969322237222,0.0348588523240148,-0.1967746802526644,1.9933274484979564,-0.3692094267674327,-0.6583020446262418,1.4027910875879954,0.37789124027862775,-1.7329818849185776,-0.11278048268758513,-0.16300366701431568,-0.5661333020712928,-0.6212288478544631,-0.5661333020712928,1.9072797273295248,0.5406573616707142,1.3784966610797764,-0.79027866305354,-0.6212288478544631,0.6839663996681922,-0.16300366701431568,0.6414242418555797,0.2713647192914942,2.0462929128969036
3,069
Endoplasmic reticulum golgi intermediate compartment
22
47
2.51843
0.011788
P07237,Q02818,Q03519,Q9BVK6,Q15904,Q9Y282,Q8N511,P56962,Q13190,O15258,P80303,Q12907,Q9Y3B3,O15260,O75396,Q10472,Q9Y3A6,Q14789,P49755,O95070,P51572,Q96GC9
Localization
GO Cellular component
msigdb_gocc
512,2,261,654,266,17,23,669,429,558,55,571,321,322,447,337,482,615,228,248,377,124
558,322,801,447,248,512,2282,2745,1960,790,228,2288,377,2420,2259,1321,669,684,55,2,261,1207,337,571,429,615,1132,266,2780,915,23,1381,2489,831,124,1050,654,1214,813,2436,2585,1594,17,482,321,2533,3052
0.5984987511004508,1.11545308586704,0.3173078764001649,0.781775583130449,1.390659754720825,0.669827883440752,-0.5479033919239744,-0.847927384389837,-0.3692094267674327,0.33252539041368356,1.4868337902652249,-0.5479033919239744,0.931509813270278,-0.6212288478544631,-0.529740355465412,-0.04660999391817365,0.45256174173642805,0.43772031258177796,2.862708171124781,4.125669255470878,1.3418152746816723,0.018673868634717674,1.0505819654024655,0.5841039652256301,0.8093547404733235,0.5260869274788118,0.06706796620069248,1.317199369207603,-0.8867326554727312,0.22497962854566572,3.475941491201594,-0.07958302654545266,-0.6583020446262418,0.30204211533490194,2.129773251435637,0.13085185405757133,0.4821074349746622,0.018673868634717674,0.3173078764001649,-0.6212288478544631,-0.7144356079504978,-0.17986003989876528,3.544036436727491,0.740103779395975,1.1283203698531714,-0.6769429135129599,-2.421230489514741
3,069
Thioredoxin, conserved site [IPR017937]
6
11
2.517875
0.011807
P07237,O43396,Q9H3N1,Q96JJ7,O95881,Q9H1E5
Sequence
InterPro Conserved site
interpro_conserved_site
512,268,14,495,369,84
268,369,512,1468,1668,1132,603,1089,495,84,14
1.304842448283804,0.9448896451261036,0.669827883440752,-0.1294642520833557,-0.23078025553282336,0.06706796620069248,0.5406573616707142,0.09906477879078189,0.7121179729480956,2.525471026963564,3.5664976928721157
3,069
Protein maturation
23
65
2.514889
0.011907
Q92896,P62942,Q9BU89,Q8N4Q1,Q99797,P49366,Q5JRX3,Q10713,P67812,Q969M3,O75503,Q8TAD4,P35670,P42892,Q9UG56,Q9UMS0,O75844,Q86UY6,Q15392,Q8TCT9,Q96F07,Q15005,Q96HE7
Processes and pathways
GO Biological process
msigdb_gobp
257,392,147,412,286,555,431,177,309,574,58,60,195,68,69,460,73,206,96,113,502,506,251
1163,2498,1312,1428,58,73,589,2921,1562,2825,3019,1195,2500,2162,2793,2742,2131,2926,2745,1843,195,723,68,555,2288,1741,392,309,670,1676,177,2074,737,506,96,431,937,828,938,2005,206,412,60,113,629,257,574,502,251,1931,1798,286,2338,767,147,943,1824,1246,1190,1029,69,1309,460,1385,865
0.0348588523240148,-0.6769429135129599,-0.04660999391817365,-0.11278048268758513,2.8363003459677576,2.71093528756688,0.5551835148202413,-1.1260894774260504,-0.17986003989876528,-0.9455105077664233,-1.5743515872010667,0.018673868634717674,-0.6769429135129599,-0.4756480043806108,-0.9062487336772611,-0.847927384389837,-0.45774800066276633,-1.1465595896590495,-0.847927384389837,-0.3168403575565848,1.6619426173233864,0.39291854449948976,2.7561169853489744,0.6128502332132403,-0.5479033919239744,-0.26502341218255865,0.8911412130144085,1.1411524269414506,0.45256174173642805,-0.23078025553282336,1.7862524375899929,-0.42214155708180023,0.37789124027862775,0.6839663996681922,2.4297657388802323,0.8093547404733235,0.2094183652836215,0.30204211533490194,0.2094183652836215,-0.3867903586863053,1.5926941854384824,0.836774272954116,2.818607017092348,2.2521766001450425,0.5114719629049498,1.366301653124708,0.5841039652256301,0.6980630201166272,1.390659754720825,-0.3516910545716578,-0.28223504260053384,1.242561719212632,-0.5661333020712928,0.36281679569392605,1.950506657749701,0.2094183652836215,-0.2995072265011157,0.002434827265685641,0.0348588523240148,0.14666752913432865,2.7561169853489744,-0.030206765888258928,0.7679256085196353,-0.07958302654545266,0.2713647192914942
3,069
Mitochondrial transport
24
85
4.512671
0.000006
Q99595,O75431,O60830,Q5JRX3,Q9UII2,Q8N4Q1,P55786,O43772,P62072,Q9NS69,Q8N4H5,O75964,O95831,P00846,Q96EK5,P51572,P52789,Q9UBX3,Q10713,P30536,P10809,P23786,Q9Y584,P45880
Processes and pathways
GO Biological process
msigdb_gobp
1,129,3,135,277,281,29,30,35,37,168,164,47,48,309,304,54,61,63,62,67,71,206,82
1268,578,324,538,1011,30,901,3,129,2111,2347,164,1560,1762,2863,1672,47,1050,48,787,2318,579,1490,1448,67,837,2355,71,596,1563,1567,2892,62,2719,1611,1810,82,2510,2698,2290,2663,1211,304,54,29,2541,2742,35,2038,63,528,2881,546,1877,135,935,2668,624,1024,168,281,2092,644,918,309,1957,857,1,1386,651,1475,2574,37,415,519,2441,61,277,1709,1041,464,1660,1795,206,898
0.06075207585543244,0.5445498022102282,0.9745934839969964,0.5831665537177918,0.20594406201738086,3.2629355088956906,0.28734925259536537,5.2463558434033315,1.755017902438807,-0.37498370593819524,-0.5123471685626237,1.5439879600324522,-0.08809313147642339,-0.1967696756540376,-1.0720047225067588,-0.15305642137327874,2.9095613097442943,0.18541815644919601,2.828507838484861,0.36766308597378367,-0.48922397649791893,0.5445498022102282,-0.04518062083477163,-0.023841256620529036,2.479979715840823,0.3276404579340653,-0.5123471685626237,2.4513039614701353,0.5251490219198828,-0.08809313147642339,-0.08809313147642339,-1.1493096241126755,2.5227650035140203,-0.846337207731496,-0.10966761131742196,-0.21874974673644393,2.291351313235633,-0.6293870511821238,-0.8218157142372212,-0.466193636337998,-0.7730909119134232,0.10259909234784996,1.028541431481072,2.6912409052071338,3.3137893104134357,-0.6530862299701407,-0.870966205891029,3.173038106570192,-0.32991397869372496,2.5227650035140203,0.6023834314782517,-1.0976531860685463,0.5831665537177918,-0.24081308138985025,1.7390277478764706,0.2671016139278185,-0.7730909119134232,0.5056860253852515,0.20594406201738086,1.5439879600324522,1.0997537049510915,-0.352404915981256,0.4861603459201101,0.28734925259536537,1.028541431481072,-0.28519250509560184,0.3276404579340653,5.607126007314287,0.01860695727689387,0.4861603459201101,-0.023841256620529036,-0.6768846808311808,3.0950455921596225,0.7726690043688413,0.6215399062476421,-0.5588756278369662,2.5369664740970035,1.1174307587509755,-0.15305642137327874,0.20594406201738086,0.6975705077026153,-0.1313218114585807,-0.1967696756540376,1.376793299425508,0.3075286897083836
3,068
Protein localization
24
77
4.062064
0.000049
Q99595,O75431,O60830,P34913,Q5JRX3,O14975,Q9NX63,Q15067,P21796,Q13505,P62072,Q9NS69,Q8N4H5,Q9NR77,O15254,Q13011,O75381,O75874,P56589,Q10713,P10809,P50402,Q9Y584,Q9BY49
Processes and pathways
Reactome Pathways
msigdb_reactome
1,129,3,252,135,271,284,153,26,34,35,37,168,39,163,53,183,184,186,63,67,199,206,98
1712,834,538,271,2966,163,1011,1520,539,781,901,3,183,2482,129,2111,2937,1804,184,1560,1050,579,1200,3051,904,67,837,2381,2019,26,1942,1563,443,252,1525,1728,3013,431,466,581,199,444,1769,186,1817,35,63,53,1419,34,153,546,135,568,569,168,281,1378,644,2570,1383,1,2404,675,98,1475,39,37,284,974,1709,464,1441,1795,206,898,2602
-0.17487213994712986,0.3276404579340653,0.5831665537177918,1.1174307587509755,-1.6092633369355172,1.5439879600324522,0.20594406201738086,-0.06659769170249044,0.5831665537177918,0.36766308597378367,0.28734925259536537,5.2463558434033315,1.4609385656230889,-0.6057861853170178,1.755017902438807,-0.37498370593819524,-1.3879650158965786,-0.21874974673644393,1.4609385656230889,-0.08809313147642339,0.18541815644919601,0.5445498022102282,0.10259909234784996,-3.3352584871652997,0.28734925259536537,2.479979715840823,0.3276404579340653,-0.5355640891226179,-0.32991397869372496,3.3768405242302353,-0.28519250509560184,-0.08809313147642339,0.7164314736036477,1.1701647502089938,-0.06659769170249044,-0.17487213994712986,-2.206425514793436,0.7352346048678885,0.6786512911522774,0.5445498022102282,1.393711643953349,0.7164314736036477,-0.1967696756540376,1.4609385656230889,-0.21874974673644393,3.173038106570192,2.5227650035140203,2.718916860246102,-0.002578945554693851,3.1988418981671183,1.6259741587923113,0.5831665537177918,1.7390277478764706,0.5638888275083017,0.5638888275083017,1.5439879600324522,1.0997537049510915,0.01860695727689387,0.4861603459201101,-0.6768846808311808,0.01860695727689387,5.607126007314287,-0.5355640891226179,0.46657151131633234,2.1123532850892897,-0.023841256620529036,3.0819609728934294,3.0950455921596225,1.0997537049510915,0.24678523442313263,-0.15305642137327874,0.6975705077026153,-0.002578945554693851,-0.1967696756540376,1.376793299425508,0.3075286897083836,-0.7007833776950536
3,068
Regulation of rna splicing
37
87
3.850537
0.000118
Q9Y5S9,P84103,Q08170,Q96PU8,P31942,Q8WVV9,Q13242,P52597,P55795,P61978,P08621,Q9NW64,Q07955,P52756,P22626,Q14011,Q5BKZ1,O75525,P31943,Q13595,Q9BWF3,P31483,O75494,Q92841,P49756,P35637,Q8IY67,Q9Y2W1,Q16629,P98175,P62995,Q9UKA9,P98179,Q96E39,Q96T37,P38159,P09651
Processes and pathways
GO Biological process
msigdb_gobp
656,515,639,403,148,550,287,161,291,165,416,576,305,316,193,77,207,221,222,603,230,598,225,487,483,107,241,509,239,113,237,508,238,372,648,121,373
1798,981,924,225,221,1935,416,373,2198,1522,811,927,788,193,1725,1451,1243,2587,598,148,222,107,121,1133,483,1018,1457,161,316,906,291,165,2614,237,515,113,238,1418,959,2825,1644,665,305,639,2428,1322,844,1285,287,913,1216,1459,603,77,1325,2516,1501,1421,1462,1463,239,1069,2326,207,2921,241,2365,550,487,749,372,1745,1748,403,772,2000,648,1265,230,1345,576,1845,1481,508,1710,509,656
-0.21874974673644393,0.22639956807078465,0.2671016139278185,1.2743240411753736,1.308665078179497,-0.28519250509560184,0.7539803128603124,0.8652711404402968,-0.42040806915777756,-0.06659769170249044,0.3476850834343582,0.2671016139278185,0.36766308597378367,1.4274138464340491,-0.17487213994712986,-0.023841256620529036,0.08171253983816708,-0.7007833776950536,0.5251490219198828,1.6422465835604534,1.308665078179497,2.0210005586439856,1.8027528778561381,0.14415287198928353,0.6596734032206868,0.20594406201738086,-0.023841256620529036,1.5604692368945314,0.9926281316895823,0.28734925259536537,1.0642490482683848,1.5439879600324522,-0.7247833095835103,1.2224597043032575,0.6215399062476421,1.9127890891523045,1.2224597043032575,-0.002578945554693851,0.24678523442313263,-0.9957630474480167,-0.1313218114585807,0.46657151131633234,1.028541431481072,0.4861603459201101,-0.5588756278369662,0.0397170883507323,0.3276404579340653,0.06075207585543244,1.0820265786552659,0.28734925259536537,0.10259909234784996,-0.023841256620529036,0.5251490219198828,2.3645324902354954,0.0397170883507323,-0.6293870511821238,-0.04518062083477163,-0.002578945554693851,-0.023841256620529036,-0.023841256620529036,1.2224597043032575,0.18541815644919601,-0.48922397649791893,1.3598297542426683,-1.2806102616573998,1.2224597043032575,-0.5123471685626237,0.5831665537177918,0.6596734032206868,0.4074212698722162,0.8836260278264877,-0.17487213994712986,-0.17487213994712986,0.7913010816735053,0.38757497902500176,-0.30751010202821283,0.4861603459201101,0.08171253983816708,1.2743240411753736,0.0397170883507323,0.5638888275083017,-0.21874974673644393,-0.023841256620529036,0.6406364183831849,-0.15305642137327874,0.6406364183831849,0.4861603459201101
3,068
Regulation of mrna processing
31
85
3.362003
0.000774
Q9Y5S9,Q8N684,P84103,Q08170,Q96PU8,Q13242,Q07666,P61978,P08621,P52756,P22626,P09012,Q14011,O43865,O75525,Q13595,Q9BWF3,P31483,O75494,Q92841,P49756,Q8IY67,Q9Y2W1,Q16629,P98175,P62995,P98179,Q96E39,Q96T37,P38159,P09651
Processes and pathways
GO Biological process
msigdb_gobp
656,517,515,639,403,287,665,165,416,316,193,450,77,333,221,603,230,598,225,487,483,241,509,239,113,237,238,372,648,121,373
1442,1798,1397,333,1013,225,221,1935,416,450,373,2198,1522,811,927,905,788,1277,193,1451,1243,2587,598,121,483,2034,1018,1457,316,906,165,237,515,113,238,1418,2825,1644,665,639,1534,2428,1285,287,1216,1459,603,77,1825,2516,1421,2399,1462,1463,239,1503,1069,2326,1070,2051,1878,1740,1289,2259,241,2365,517,1171,487,749,372,1745,1748,403,2000,1836,648,1265,230,1034,705,1481,1710,509,656
-0.023841256620529036,-0.21874974673644393,-0.002578945554693851,0.95650636817542,0.20594406201738086,1.2743240411753736,1.308665078179497,-0.28519250509560184,0.7539803128603124,0.6975705077026153,0.8652711404402968,-0.42040806915777756,-0.06659769170249044,0.3476850834343582,0.2671016139278185,0.28734925259536537,0.36766308597378367,0.06075207585543244,1.4274138464340491,-0.023841256620529036,0.08171253983816708,-0.7007833776950536,0.5251490219198828,1.8027528778561381,0.6596734032206868,-0.32991397869372496,0.20594406201738086,-0.023841256620529036,0.9926281316895823,0.28734925259536537,1.5439879600324522,1.2224597043032575,0.6215399062476421,1.9127890891523045,1.2224597043032575,-0.002578945554693851,-0.9957630474480167,-0.1313218114585807,0.46657151131633234,0.4861603459201101,-0.06659769170249044,-0.5588756278369662,0.06075207585543244,1.0820265786552659,0.10259909234784996,-0.023841256620529036,0.5251490219198828,2.3645324902354954,-0.21874974673644393,-0.6293870511821238,-0.002578945554693851,-0.5355640891226179,-0.023841256620529036,-0.023841256620529036,1.2224597043032575,-0.04518062083477163,0.18541815644919601,-0.48922397649791893,0.18541815644919601,-0.32991397869372496,-0.24081308138985025,-0.17487213994712986,0.06075207585543244,-0.4432552843005688,1.2224597043032575,-0.5123471685626237,0.6215399062476421,0.1234123375751231,0.6596734032206868,0.4074212698722162,0.8836260278264877,-0.17487213994712986,-0.17487213994712986,0.7913010816735053,-0.30751010202821283,-0.21874974673644393,0.4861603459201101,0.08171253983816708,1.2743240411753736,0.20594406201738086,0.4469190437544668,-0.023841256620529036,-0.15305642137327874,0.6406364183831849,0.4861603459201101
3,068
Calcium-binding protein
8
17
3.266137
0.00109
Q8IYU8,Q14257,Q9BPX6,Q15293,P43307,P80303,Q02818,O43852
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
229,38,231,234,110,17,85,94
94,2240,1674,813,278,110,1369,17,85,38,234,1377,229,718,858,231,1603
2.1575588520544753,-0.4432552843005688,-0.15305642137327874,0.3476850834343582,1.0997537049510915,1.9748431337622516,0.01860695727689387,3.7078859087178495,2.247053105231329,3.0819609728934294,1.2397952544690163,0.01860695727689387,1.2743240411753736,0.42720245971240756,0.3276404579340653,1.2570832659186544,-0.08809313147642339
3,068
RNA recognition motif domain [IPR000504]
59
120
3.246851
0.001167
Q9Y5S9,Q8N684,P84103,Q96PK6,Q08170,Q15717,O95104,P23588,P23246,P31942,Q93062,Q8WVV9,Q8WXF1,Q13242,Q15233,P52597,Q9P2N5,Q14103,P55795,Q13151,P08621,Q99729,Q86U42,Q9NW64,Q9NWH9,O60506,Q92804,Q07955,Q9UKM9,P51991,P52756,P22626,Q9Y4C8,P09012,Q14011,Q86V81,P31943,Q13595,O14979,Q01844,Q9BWF3,P31483,O75494,O43390,P49756,P35637,Q96I25,Q8IY67,Q16629,P98175,P62995,P07910,P98179,Q96E39,Q9Y6M1,Q9UKA9,Q96T37,P38159,P09651
Sequence
InterPro Domain
interpro_domain
656,517,515,140,639,529,265,272,524,148,671,550,670,287,288,161,295,544,291,299,416,310,434,576,705,181,55,305,449,311,316,193,732,450,77,606,222,603,220,601,230,598,225,224,483,107,501,241,239,113,237,236,238,372,380,508,648,121,373
1893,220,1850,1150,224,2818,181,225,982,265,1935,1765,236,2016,416,450,373,1094,1522,905,788,193,524,272,1451,1243,598,148,222,790,107,121,2121,1058,483,311,1529,161,316,291,2458,237,766,515,113,238,2394,818,601,2809,305,639,844,2168,299,287,913,1216,2702,961,603,77,544,1825,2516,1647,2641,2880,288,2399,1462,529,239,1503,2326,1023,1505,434,606,1828,2921,241,3025,517,1543,1429,550,1653,670,55,749,671,1785,372,1745,501,140,648,1837,310,1265,230,1389,1707,1003,1345,2372,576,705,1753,729,295,1481,508,449,2009,1189,732,656,380
-0.2629604179518373,1.308665078179497,-0.24081308138985025,0.1234123375751231,1.2743240411753736,-0.9957630474480167,1.477635046154892,1.2743240411753736,0.22639956807078465,1.135058068236522,-0.28519250509560184,-0.1967696756540376,1.2224597043032575,-0.32991397869372496,0.7539803128603124,0.6975705077026153,0.8652711404402968,0.1648212844721815,-0.06659769170249044,0.28734925259536537,0.36766308597378367,1.4274138464340491,0.6023834314782517,1.1174307587509755,-0.023841256620529036,0.08171253983816708,0.5251490219198828,1.6422465835604534,1.308665078179497,0.36766308597378367,2.0210005586439856,1.8027528778561381,-0.37498370593819524,0.18541815644919601,0.6596734032206868,1.0106106643811552,-0.06659769170249044,1.5604692368945314,0.9926281316895823,1.0642490482683848,-0.582282687700334,1.2224597043032575,0.38757497902500176,0.6215399062476421,1.9127890891523045,1.2224597043032575,-0.5355640891226179,0.3476850834343582,0.5251490219198828,-0.9705795993316118,1.028541431481072,0.4861603459201101,0.3276404579340653,-0.39765115198872797,1.0464207787332467,1.0820265786552659,0.28734925259536537,0.10259909234784996,-0.8218157142372212,0.24678523442313263,0.5251490219198828,2.3645324902354954,0.5831665537177918,-0.21874974673644393,-0.6293870511821238,-0.1313218114585807,-0.7488854809308932,-1.0976531860685463,1.0820265786552659,-0.5355640891226179,-0.023841256620529036,0.6023834314782517,1.2224597043032575,-0.04518062083477163,-0.48922397649791893,0.20594406201738086,-0.04518062083477163,0.7352346048678885,0.5251490219198828,-0.21874974673644393,-1.2806102616573998,1.2224597043032575,-2.4327212324163647,0.6215399062476421,-0.06659769170249044,-0.002578945554693851,0.5831665537177918,-0.1313218114585807,0.46657151131633234,2.649513999332004,0.4074212698722162,0.46657151131633234,-0.1967696756540376,0.8836260278264877,-0.17487213994712986,0.6406364183831849,1.7229979679808267,0.4861603459201101,-0.21874974673644393,1.028541431481072,0.08171253983816708,1.2743240411753736,0.01860695727689387,-0.15305642137327874,0.22639956807078465,0.0397170883507323,-0.5123471685626237,0.5638888275083017,0.4469190437544668,-0.17487213994712986,0.42720245971240756,1.0642490482683848,-0.023841256620529036,0.6406364183831849,0.7164314736036477,-0.30751010202821283,0.1234123375751231,0.42720245971240756,0.4861603459201101,0.8652711404402968
3,068
Outer membrane
21
83
3.168596
0.001532
O75431,P57105,Q5HYI7,P33121,Q6NUM9,Q9NX63,P21796,Q13505,Q9UKU0,Q9NS69,Q8N4H5,P61970,P52789,P30536,Q96TC7,Q99536,P50402,P45880,O00264,O43169,Q9BUK6
Localization
GO Cellular component
msigdb_gocc
129,261,14,398,414,284,26,34,296,37,168,41,54,62,322,331,199,82,212,87,352
1268,212,1269,3061,87,2480,1194,1851,129,1560,1762,1806,1050,1937,2801,1448,904,1311,26,62,398,1728,1809,1862,82,199,1211,54,1733,261,41,3008,34,1102,2881,583,1877,14,886,641,414,1741,2644,1783,498,624,1024,168,797,938,1378,644,2402,854,721,2571,1383,1228,322,331,1143,1079,352,803,1388,651,2145,2557,1342,37,2977,754,1145,284,1437,1556,2751,1117,296,1007,1660,1795,429
0.06075207585543244,1.3428207261393184,0.06075207585543244,-4.5909756540004745,2.2024571855190804,-0.6057861853170178,0.10259909234784996,-0.24081308138985025,1.755017902438807,-0.08809313147642339,-0.1967696756540376,-0.21874974673644393,0.18541815644919601,-0.28519250509560184,-0.9705795993316118,-0.023841256620529036,0.28734925259536537,0.0397170883507323,3.3768405242302353,2.5227650035140203,0.7913010816735053,-0.17487213994712986,-0.21874974673644393,-0.24081308138985025,2.291351313235633,1.393711643953349,0.10259909234784996,2.6912409052071338,-0.17487213994712986,1.1526359582235532,3.0688515315547056,-2.1124017795924295,3.1988418981671183,0.1648212844721815,-1.0976531860685463,0.5445498022102282,-0.24081308138985025,3.9551111632718845,0.3075286897083836,0.4861603459201101,0.7726690043688413,-0.17487213994712986,-0.7488854809308932,-0.1967696756540376,0.6406364183831849,0.5056860253852515,0.20594406201738086,1.5439879600324522,0.36766308597378367,0.2671016139278185,0.01860695727689387,0.4861603459201101,-0.5355640891226179,0.3276404579340653,0.42720245971240756,-0.6768846808311808,0.01860695727689387,0.10259909234784996,0.9926281316895823,0.9745934839969964,0.14415287198928353,0.18541815644919601,0.9201733007142913,0.36766308597378367,0.01860695727689387,0.4861603459201101,-0.37498370593819524,-0.6530862299701407,0.0397170883507323,3.0950455921596225,-1.6660387305018811,0.4074212698722162,0.14415287198928353,1.0997537049510915,-0.002578945554693851,-0.06659769170249044,-0.870966205891029,0.1648212844721815,1.0642490482683848,0.22639956807078465,-0.1313218114585807,-0.1967696756540376,0.7539803128603124
3,068
Mitochondrial protein import
13
36
3.12664
0.001768
O75431,Q99595,O60830,Q13505,P62072,Q9NS69,Q8N4H5,Q5JRX3,P10809,Q9Y584,Q9NX63,P21796,Q10713
Processes and pathways
Reactome Pathways
msigdb_reactome
129,1,3,34,35,37,168,135,67,206,284,26,63
538,1011,901,3,2482,129,2111,1804,1560,1050,579,1200,67,837,2381,26,1563,1728,35,63,34,546,135,168,281,1383,1,2404,1475,37,284,1709,464,1795,206,898
0.5831665537177918,0.20594406201738086,0.28734925259536537,5.2463558434033315,-0.6057861853170178,1.755017902438807,-0.37498370593819524,-0.21874974673644393,-0.08809313147642339,0.18541815644919601,0.5445498022102282,0.10259909234784996,2.479979715840823,0.3276404579340653,-0.5355640891226179,3.3768405242302353,-0.08809313147642339,-0.17487213994712986,3.173038106570192,2.5227650035140203,3.1988418981671183,0.5831665537177918,1.7390277478764706,1.5439879600324522,1.0997537049510915,0.01860695727689387,5.607126007314287,-0.5355640891226179,-0.023841256620529036,3.0950455921596225,1.0997537049510915,-0.15305642137327874,0.6975705077026153,-0.1967696756540376,1.376793299425508,0.3075286897083836
3,068
Negative regulation of mrna splicing via spliceosome
6
15
2.98371
0.002848
P22626,O75494,P61978,Q16629,P98175,P38159
Processes and pathways
GO Biological process
msigdb_gobp
193,225,165,239,113,121
1798,225,193,1451,1243,121,165,113,1644,639,1285,287,1216,239,1265
-0.21874974673644393,1.2743240411753736,1.4274138464340491,-0.023841256620529036,0.08171253983816708,1.8027528778561381,1.5439879600324522,1.9127890891523045,-0.1313218114585807,0.4861603459201101,0.06075207585543244,1.0820265786552659,0.10259909234784996,1.2224597043032575,0.08171253983816708
3,068
Intracellular calcium-sensing protein
7
14
2.965543
0.003021
Q8IYU8,Q14257,Q9BPX6,Q15293,P80303,Q02818,O43852
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
229,38,231,234,17,85,94
94,2240,813,278,1369,17,85,38,234,1377,229,718,858,231
2.1575588520544753,-0.4432552843005688,0.3476850834343582,1.0997537049510915,0.01860695727689387,3.7078859087178495,2.247053105231329,3.0819609728934294,1.2397952544690163,0.01860695727689387,1.2743240411753736,0.42720245971240756,0.3276404579340653,1.2570832659186544
3,068
Calmodulin
7
14
2.965543
0.003021
Q8IYU8,Q14257,Q9BPX6,Q15293,P80303,Q02818,O43852
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
229,38,231,234,17,85,94
94,2240,813,278,1369,17,85,38,234,1377,229,718,858,231
2.1575588520544753,-0.4432552843005688,0.3476850834343582,1.0997537049510915,0.01860695727689387,3.7078859087178495,2.247053105231329,3.0819609728934294,1.2397952544690163,0.01860695727689387,1.2743240411753736,0.42720245971240756,0.3276404579340653,1.2570832659186544
3,068