term
stringlengths 2
121
| overlap
int64 6
281
| setsize
int64 7
499
| score
float64 1.96
10.6
| pval
float64 0
0.05
| edge
stringlengths 41
1.97k
| type
stringclasses 5
values | subtype
stringclasses 24
values | subtype_key
stringclasses 24
values | edge_idxs
stringlengths 11
1.17k
| ann_idxs
stringlengths 19
2.31k
| ann_vals
stringlengths 124
9.94k
| sig_size
int64 2.2k
3.73k
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Lytic vacuole organization
| 9
| 20
| 2.73611
| 0.006217
|
P50897,O14773,P11117,Q8NHS3,O75503,P54802,Q14108,P04062,Q8N511
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
68,100,206,20,21,83,84,87,60
|
1702,100,21,722,87,2080,301,206,501,68,2333,83,1884,84,2667,60,20,2408,1633,2675
|
-0.25395864506177507,2.0407291615321252,3.4527621477763786,0.3341012059117994,2.24427219514418,-0.457189555658307,0.9903454141911546,1.3072002040011301,0.5791408457585902,2.4547035837208413,-0.6383986218099443,2.310095682444116,-0.34001843888349026,2.277306408278314,-1.1912964858988957,2.517478261676434,3.490212452974606,-0.7003227426014513,-0.19742355434165754,-1.1912964858988957
| 2,812
|
Cyclin a cdk2 associated events at s phase entry
| 10
| 40
| 2.717724
| 0.006573
|
P25788,P28074,Q99436,P20618,P31751,P28072,P28070,P49721,P60900,P49720
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
292,70,199,102,227,45,110,18,120,314
|
514,2072,1481,2383,1271,347,725,1917,102,955,1970,1558,292,1288,1087,110,45,70,227,1775,1131,845,314,18,2267,120,568,926,1666,1139,666,1449,2272,2546,1987,1149,199,1531,512,1643
|
0.5552017244663052,-0.457189555658307,-0.1415423442786107,-0.7003227426014513,-0.031687014709587694,0.8347092158473343,0.3341012059117994,-0.36904762138247893,2.005881846159429,0.15470992714805706,-0.39825124132052653,-0.16940208304943802,1.012159267293361,-0.031687014709587694,0.07571238201592677,1.899680038524244,2.759934875525814,2.4229764762472206,1.2248145512604927,-0.28247580804102473,0.04908726812999223,0.23242134673518783,0.946407369350807,3.539634851198567,-0.5772466087129535,1.8274547643749006,0.5069552146823165,0.1807547309326192,-0.2256084890274861,0.04908726812999223,0.38413580421459165,-0.11384263369455079,-0.5772466087129535,-0.8909116443167836,-0.39825124132052653,0.04908726812999223,1.3478444644435112,-0.1415423442786107,0.5791408457585902,-0.19742355434165754
| 2,812
|
Hedgehog off state
| 11
| 46
| 2.703563
| 0.00686
|
P25788,P28074,Q99436,P68371,P20618,P28072,P28070,P49721,Q9BVA1,P60900,P49720
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
292,70,199,261,102,45,110,18,248,120,314
|
514,2072,1481,2383,1271,347,520,2023,1332,1917,102,1970,1558,292,1288,1087,110,45,70,1775,1131,845,786,314,18,2267,120,568,926,1666,1139,666,261,1449,2272,1987,1148,1149,2405,1902,199,1531,682,248,512,1643
|
0.5552017244663052,-0.457189555658307,-0.1415423442786107,-0.7003227426014513,-0.031687014709587694,0.8347092158473343,0.5552017244663052,-0.4276312314054814,-0.05891660926003703,-0.36904762138247893,2.005881846159429,-0.39825124132052653,-0.16940208304943802,1.012159267293361,-0.031687014709587694,0.07571238201592677,1.899680038524244,2.759934875525814,2.4229764762472206,-0.28247580804102473,0.04908726812999223,0.23242134673518783,0.2835332284224711,0.946407369350807,3.539634851198567,-0.5772466087129535,1.8274547643749006,0.5069552146823165,0.1807547309326192,-0.2256084890274861,0.04908726812999223,0.38413580421459165,1.119711996032066,-0.11384263369455079,-0.5772466087129535,-0.39825124132052653,0.04908726812999223,0.04908726812999223,-0.7003227426014513,-0.34001843888349026,1.3478444644435112,-0.1415423442786107,0.38413580421459165,1.1620412739234138,0.5791408457585902,-0.19742355434165754
| 2,812
|
Defective cftr causes cystic fibrosis
| 12
| 40
| 2.69769
| 0.006982
|
O75832,P25788,P28074,Q99436,P20618,P28072,O75477,P28070,P49721,Q9UL46,P60900,P49720
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
347,292,70,199,102,45,519,110,18,512,120,314
|
514,2072,1481,2383,1271,519,347,1704,1917,102,1970,1558,292,1288,1087,110,45,70,1775,1131,845,314,18,2267,2142,120,568,926,1666,1139,1449,2272,1148,1149,199,1531,977,1742,512,1643
|
0.5552017244663052,-0.457189555658307,-0.1415423442786107,-0.7003227426014513,-0.031687014709587694,0.5552017244663052,0.8347092158473343,-0.25395864506177507,-0.36904762138247893,2.005881846159429,-0.39825124132052653,-0.16940208304943802,1.012159267293361,-0.031687014709587694,0.07571238201592677,1.899680038524244,2.759934875525814,2.4229764762472206,-0.28247580804102473,0.04908726812999223,0.23242134673518783,0.946407369350807,3.539634851198567,-0.5772466087129535,-0.48692821008242365,1.8274547643749006,0.5069552146823165,0.1807547309326192,-0.2256084890274861,0.04908726812999223,-0.11384263369455079,-0.5772466087129535,0.04908726812999223,0.04908726812999223,1.3478444644435112,-0.1415423442786107,0.15470992714805706,-0.25395864506177507,0.5791408457585902,-0.19742355434165754
| 2,812
|
Abc transporter disorders
| 12
| 40
| 2.69769
| 0.006982
|
O75832,P25788,P28074,Q99436,P20618,P28072,O75477,P28070,P49721,Q9UL46,P60900,P49720
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
347,292,70,199,102,45,519,110,18,512,120,314
|
514,2072,1481,2383,1271,519,347,1704,1917,102,1970,1558,292,1288,1087,110,45,70,1775,1131,845,314,18,2267,2142,120,568,926,1666,1139,1449,2272,1148,1149,199,1531,977,1742,512,1643
|
0.5552017244663052,-0.457189555658307,-0.1415423442786107,-0.7003227426014513,-0.031687014709587694,0.5552017244663052,0.8347092158473343,-0.25395864506177507,-0.36904762138247893,2.005881846159429,-0.39825124132052653,-0.16940208304943802,1.012159267293361,-0.031687014709587694,0.07571238201592677,1.899680038524244,2.759934875525814,2.4229764762472206,-0.28247580804102473,0.04908726812999223,0.23242134673518783,0.946407369350807,3.539634851198567,-0.5772466087129535,-0.48692821008242365,1.8274547643749006,0.5069552146823165,0.1807547309326192,-0.2256084890274861,0.04908726812999223,-0.11384263369455079,-0.5772466087129535,0.04908726812999223,0.04908726812999223,1.3478444644435112,-0.1415423442786107,0.15470992714805706,-0.25395864506177507,0.5791408457585902,-0.19742355434165754
| 2,812
|
Alcohol binding
| 7
| 17
| 2.690299
| 0.007139
|
P30536,P29375,Q9BZF1,P21796,P45880,O15118,Q14108
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
0,271,307,13,17,82,84
|
2656,82,805,519,1704,300,1710,13,1968,271,0,17,414,84,2197,307,1063
|
-1.1570110616486227,2.326399504773361,0.2580459451927195,0.5552017244663052,-0.25395864506177507,0.9903454141911546,-0.25395864506177507,3.948903861103401,-0.39825124132052653,1.098400788944567,5.472379812321296,3.539634851198567,0.7202683829276397,2.277306408278314,-0.5168492233508618,0.9903454141911546,0.10219020816314191
| 2,812
|
Negative regulation of response to external stimulus
| 11
| 39
| 2.690119
| 0.007143
|
Q9UMX5,Q9H000,P14174,P01889,P80303,O14936,P28070,P19474,P04062,Q96G23,P04439
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
38,367,260,167,59,119,110,116,87,27,160
|
119,370,2134,2295,167,87,160,260,2644,116,1970,110,1290,1611,1563,1341,925,586,667,59,790,2547,1202,550,1999,736,508,1462,1211,27,1902,477,1633,367,1849,744,38,1856,1700
|
1.8274547643749006,0.789268883456853,-0.48692821008242365,-0.6077272079458682,1.4676530771754677,2.24427219514418,1.4873187834566612,1.119711996032066,-1.1229595856058519,1.8456202538155837,-0.39825124132052653,1.899680038524244,-0.031687014709587694,-0.19742355434165754,-0.16940208304943802,-0.05891660926003703,0.1807547309326192,0.4826455052953858,0.38413580421459165,2.533032514844444,0.2835332284224711,-0.8909116443167836,0.022313356391112545,0.5311402316133299,-0.39825124132052653,0.3341012059117994,0.5791408457585902,-0.11384263369455079,0.022313356391112545,3.3512432407507826,-0.34001843888349026,0.6266565061101952,-0.19742355434165754,0.8120443818425275,-0.311161791776721,0.3341012059117994,3.0035225327511377,-0.311161791776721,-0.2256084890274861
| 2,812
|
Tnfr2 non canonical nf kb pathway
| 9
| 39
| 2.682274
| 0.007312
|
P25788,P28074,Q99436,P20618,P28072,P28070,P49721,P60900,P49720
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
292,70,199,102,45,110,18,120,314
|
514,2072,1481,2383,1271,347,1917,102,1970,1558,292,1288,1087,110,45,70,1775,1131,845,314,18,2267,120,2501,568,926,1666,1139,666,1449,2272,1987,1148,1149,1253,199,1531,512,1643
|
0.5552017244663052,-0.457189555658307,-0.1415423442786107,-0.7003227426014513,-0.031687014709587694,0.8347092158473343,-0.36904762138247893,2.005881846159429,-0.39825124132052653,-0.16940208304943802,1.012159267293361,-0.031687014709587694,0.07571238201592677,1.899680038524244,2.759934875525814,2.4229764762472206,-0.28247580804102473,0.04908726812999223,0.23242134673518783,0.946407369350807,3.539634851198567,-0.5772466087129535,1.8274547643749006,-0.8265602308855787,0.5069552146823165,0.1807547309326192,-0.2256084890274861,0.04908726812999223,0.38413580421459165,-0.11384263369455079,-0.5772466087129535,-0.39825124132052653,0.04908726812999223,0.04908726812999223,-0.004610885946918551,1.3478444644435112,-0.1415423442786107,0.5791408457585902,-0.19742355434165754
| 2,812
|
Dectin 1 mediated noncanonical nf kb signaling
| 9
| 39
| 2.682274
| 0.007312
|
P25788,P28074,Q99436,P20618,P28072,P28070,P49721,P60900,P49720
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
292,70,199,102,45,110,18,120,314
|
514,2072,1481,2383,1271,347,1917,102,1970,1558,292,1288,1087,110,45,70,1775,1131,845,314,18,2267,120,2501,568,926,1666,1139,666,1449,2272,1987,1148,1149,1253,199,1531,512,1643
|
0.5552017244663052,-0.457189555658307,-0.1415423442786107,-0.7003227426014513,-0.031687014709587694,0.8347092158473343,-0.36904762138247893,2.005881846159429,-0.39825124132052653,-0.16940208304943802,1.012159267293361,-0.031687014709587694,0.07571238201592677,1.899680038524244,2.759934875525814,2.4229764762472206,-0.28247580804102473,0.04908726812999223,0.23242134673518783,0.946407369350807,3.539634851198567,-0.5772466087129535,1.8274547643749006,-0.8265602308855787,0.5069552146823165,0.1807547309326192,-0.2256084890274861,0.04908726812999223,0.38413580421459165,-0.11384263369455079,-0.5772466087129535,-0.39825124132052653,0.04908726812999223,0.04908726812999223,-0.004610885946918551,1.3478444644435112,-0.1415423442786107,0.5791408457585902,-0.19742355434165754
| 2,812
|
Cytokine signaling in immune system
| 52
| 165
| 2.676238
| 0.007445
|
Q15369,P55735,P15260,Q99567,P52597,P14174,P08670,O14979,O00231,Q13126,P49721,P04083,P62993,Q14258,P57740,P22626,P04439,O00505,P25788,P11233,O00629,P52294,P01889,P28072,P46109,P49720,Q53EL6,P30154,P10321,O15344,Q9BW27,P28074,Q99436,P45985,P78417,P09601,Q15750,Q13501,Q06124,O75832,Q07820,P20618,P31751,Q9BTX1,P30153,Q8NFH4,Q02750,P28070,P19474,Q9UL46,P60900,Q12769
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
253,129,132,533,138,260,385,134,514,16,18,269,523,547,284,283,160,31,292,411,42,43,167,45,445,314,447,190,312,440,466,70,199,322,74,79,339,473,95,347,231,102,227,494,486,240,362,110,116,512,120,505
|
1267,514,2072,1481,31,42,2383,134,440,910,1271,2415,1649,950,347,167,269,2175,160,1707,1386,2176,750,2224,808,385,2300,79,2385,312,1033,411,1388,260,752,132,1332,1917,2225,1389,2644,116,1185,102,2456,1659,283,2226,1970,1558,292,1288,2590,2228,1087,110,45,70,1769,564,486,190,227,1875,1775,1235,1292,2087,1442,1717,2789,1089,1443,1131,322,445,845,314,18,1663,960,1563,1564,2267,2035,1929,923,43,138,2719,2233,925,129,284,1883,120,1240,2501,2093,568,926,1666,1139,523,1343,666,2270,2395,74,362,961,95,1449,231,505,2765,1096,16,1401,2272,1986,473,2099,1987,1831,547,1890,1051,1148,1149,253,1729,2505,339,550,965,447,1204,1997,1578,2317,971,1898,240,1253,1793,1311,1413,2484,2463,199,680,1531,533,494,2119,466,1638,1744,2698,1373,512,1643,1856,1425
|
-0.031687014709587694,0.5552017244663052,-0.457189555658307,-0.1415423442786107,3.16753088514317,2.803929621091696,-0.7003227426014513,1.6605823293503985,0.6736961261378334,0.1807547309326192,-0.031687014709587694,-0.7315799679422195,-0.2256084890274861,0.15470992714805706,0.8347092158473343,1.4676530771754677,1.098400788944567,-0.5168492233508618,1.4873187834566612,-0.25395864506177507,-0.08630127296868081,-0.5168492233508618,0.3088845403658546,-0.5469546575117772,0.2580459451927195,0.7663817253435458,-0.6077272079458682,2.342643329037244,-0.7003227426014513,0.946407369350807,0.10219020816314191,0.7202683829276397,-0.08630127296868081,1.119711996032066,0.3088845403658546,1.679431285350743,-0.05891660926003703,-0.36904762138247893,-0.5469546575117772,-0.08630127296868081,-1.1229595856058519,1.8456202538155837,0.022313356391112545,2.005881846159429,-0.7630370464216969,-0.2256084890274861,1.0554810704738096,-0.5469546575117772,-0.39825124132052653,-0.16940208304943802,1.012159267293361,-0.031687014709587694,-0.9890357013357498,-0.5469546575117772,0.07571238201592677,1.899680038524244,2.759934875525814,2.4229764762472206,-0.28247580804102473,0.5069552146823165,0.6029587324284209,1.3680320463287143,1.2248145512604927,-0.34001843888349026,-0.28247580804102473,-0.004610885946918551,-0.031687014709587694,-0.457189555658307,-0.11384263369455079,-0.25395864506177507,-2.749330655939741,0.07571238201592677,-0.11384263369455079,0.04908726812999223,0.9242813695324721,0.6736961261378334,0.23242134673518783,0.946407369350807,3.539634851198567,-0.2256084890274861,0.15470992714805706,-0.16940208304943802,-0.16940208304943802,-0.5772466087129535,-0.4276312314054814,-0.36904762138247893,0.1807547309326192,2.789314221988835,1.6605823293503985,-1.5109011257882559,-0.5469546575117772,0.1807547309326192,1.7168950201979138,1.0554810704738096,-0.34001843888349026,1.8274547643749006,-0.004610885946918551,-0.8265602308855787,-0.457189555658307,0.5069552146823165,0.1807547309326192,-0.2256084890274861,0.04908726812999223,0.5552017244663052,-0.05891660926003703,0.38413580421459165,-0.5772466087129535,-0.7003227426014513,2.3749525947181227,0.8120443818425275,0.15470992714805706,2.1096173622141015,-0.11384263369455079,1.2248145512604927,0.5791408457585902,-2.05202791259183,0.07571238201592677,3.7667680443901195,-0.08630127296868081,-0.5772466087129535,-0.39825124132052653,0.6266565061101952,-0.457189555658307,-0.39825124132052653,-0.311161791776721,0.5311402316133299,-0.34001843888349026,0.10219020816314191,0.04908726812999223,0.04908726812999223,1.1409252165655943,-0.25395864506177507,-0.8265602308855787,0.8572643679612094,0.5311402316133299,0.15470992714805706,0.6736961261378334,0.022313356391112545,-0.39825124132052653,-0.16940208304943802,-0.6077272079458682,0.15470992714805706,-0.34001843888349026,1.1830609814557924,-0.004610885946918551,-0.28247580804102473,-0.031687014709587694,-0.08630127296868081,-0.7946963348979321,-0.7630370464216969,1.3478444644435112,0.38413580421459165,-0.1415423442786107,0.5552017244663052,0.6029587324284209,-0.457189555658307,0.6502352734037639,-0.19742355434165754,-0.25395864506177507,-1.3663385868789217,-0.05891660926003703,0.5791408457585902,-0.19742355434165754,-0.311161791776721,-0.08630127296868081
| 2,812
|
Separation of sister chromatids
| 41
| 100
| 2.674926
| 0.007475
|
P55735,P68371,Q92674,O60216,O00231,P49721,Q8WYP5,Q99661,Q9BUF5,Q9H1A4,Q9HBM1,Q9UJX2,P57740,O60566,P25788,P28072,Q13042,Q9Y266,P49720,P30154,Q8NI77,Q9BW27,P61289,P28074,Q99436,Q96DE5,Q9UJX3,Q7L7X3,Q9UJX4,O75832,P20618,Q9UJX6,P30153,Q8NFH4,P28070,Q8NBT2,Q9UL46,Q15691,Q9BVA1,P60900,Q12769
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
129,261,262,381,514,18,677,681,682,683,684,555,284,658,292,45,571,717,314,190,459,466,568,70,199,462,346,221,495,347,102,496,486,240,110,629,512,624,248,120,505
|
2520,514,2072,1481,2383,1546,803,1271,1272,1760,381,658,347,1917,102,1970,1558,292,1288,1087,110,45,70,486,190,754,1775,2740,1131,1395,845,692,314,18,960,1779,2267,2233,1664,129,284,120,568,926,1666,1139,759,261,1449,505,571,2272,1002,2196,1889,1403,1890,1148,1833,1149,624,1099,1576,2614,221,1999,1057,1897,629,1898,240,459,1311,2283,677,262,462,2463,2510,199,1531,681,682,248,466,831,683,684,2655,2252,1118,555,346,495,496,512,1643,1591,717,1858
|
-0.858631173481535,0.5552017244663052,-0.457189555658307,-0.1415423442786107,-0.7003227426014513,-0.16940208304943802,0.2580459451927195,-0.031687014709587694,-0.031687014709587694,-0.28247580804102473,0.7663817253435458,0.38413580421459165,0.8347092158473343,-0.36904762138247893,2.005881846159429,-0.39825124132052653,-0.16940208304943802,1.012159267293361,-0.031687014709587694,0.07571238201592677,1.899680038524244,2.759934875525814,2.4229764762472206,0.6029587324284209,1.3680320463287143,0.3088845403658546,-0.28247580804102473,-1.6976241927614946,0.04908726812999223,-0.08630127296868081,0.23242134673518783,0.35918453124975014,0.946407369350807,3.539634851198567,0.15470992714805706,-0.28247580804102473,-0.5772466087129535,-0.5469546575117772,-0.2256084890274861,1.7168950201979138,1.0554810704738096,1.8274547643749006,0.5069552146823165,0.1807547309326192,-0.2256084890274861,0.04908726812999223,0.3088845403658546,1.119711996032066,-0.11384263369455079,0.5791408457585902,0.5069552146823165,-0.5772466087129535,0.1285222344905635,-0.5168492233508618,-0.34001843888349026,-0.08630127296868081,-0.34001843888349026,0.04908726812999223,-0.311161791776721,0.04908726812999223,0.43364725460652315,0.07571238201592677,-0.16940208304943802,-1.0221799869805437,1.2661922382132038,-0.39825124132052653,0.10219020816314191,-0.34001843888349026,0.43364725460652315,-0.34001843888349026,1.1830609814557924,0.6502352734037639,-0.031687014709587694,-0.5772466087129535,0.38413580421459165,1.119711996032066,0.6502352734037639,-0.7630370464216969,-0.8265602308855787,1.3478444644435112,-0.1415423442786107,0.38413580421459165,0.38413580421459165,1.1620412739234138,0.6502352734037639,0.2580459451927195,0.38413580421459165,0.38413580421459165,-1.1229595856058519,-0.5469546575117772,0.07571238201592677,0.5311402316133299,0.8572643679612094,0.6029587324284209,0.6029587324284209,0.5791408457585902,-0.19742355434165754,-0.16940208304943802,0.35918453124975014,-0.311161791776721
| 2,812
|
Glycosphingolipid metabolism
| 6
| 13
| 2.657519
| 0.007872
|
P16278,P10619,P07602,P06280,P06865,P04062
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
161,67,101,168,150,87
|
1274,87,168,150,101,2080,67,161,251,1346,2565,2069,1020
|
-0.031687014709587694,2.24427219514418,1.4676530771754677,1.565142433258028,2.0233395056563532,-0.457189555658307,2.4704816361758035,1.4873187834566612,1.1409252165655943,-0.05891660926003703,-0.9234041685354025,-0.4276312314054814,0.1285222344905635
| 2,812
|
Ceramide metabolic process
| 6
| 16
| 2.639201
| 0.00831
|
O15270,P06280,Q8NCC3,P06865,P04062,Q96G23
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
204,168,85,150,87,27
|
1483,204,537,87,168,150,2080,251,486,668,1346,850,85,27,905,2069
|
-0.1415423442786107,1.3072002040011301,0.5311402316133299,2.24427219514418,1.4676530771754677,1.565142433258028,-0.457189555658307,1.1409252165655943,0.6029587324284209,0.38413580421459165,-0.05891660926003703,0.23242134673518783,2.277306408278314,3.3512432407507826,0.2066580696947229,-0.4276312314054814
| 2,812
|
Epithelial cell signaling in helicobacter pylori infection
| 10
| 20
| 2.636427
| 0.008378
|
Q16539,Q07157,P45985,Q9Y487,Q93050,Q15904,P36543,Q9Y624,P61421,Q06124
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
550,544,322,41,170,239,151,249,502,95
|
2644,920,563,151,691,1089,322,1240,502,1400,95,544,239,550,170,1263,1223,41,1176,249
|
-1.1229595856058519,0.1807547309326192,0.5069552146823165,1.565142433258028,0.35918453124975014,0.07571238201592677,0.9242813695324721,-0.004610885946918551,0.5791408457585902,-0.08630127296868081,2.1096173622141015,0.5311402316133299,1.1830609814557924,0.5311402316133299,1.4676530771754677,-0.004610885946918551,0.022313356391112545,2.8619031325793367,0.04908726812999223,1.1620412739234138
| 2,812
|
Fibrous tissue neoplasm
| 9
| 18
| 2.634703
| 0.008421
|
P21912,P52701,Q15392,Q969G3,P49327,Q13126,Q15437,P10644,Q07954
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
196,600,10,201,585,16,114,520,374
|
520,920,1659,1768,196,1291,957,585,600,1044,374,1508,16,10,114,1677,201,633
|
0.5552017244663052,0.1807547309326192,-0.2256084890274861,-0.28247580804102473,1.3478444644435112,-0.031687014709587694,0.15470992714805706,0.4826455052953858,0.45820991892635715,0.10219020816314191,0.789268883456853,-0.1415423442786107,3.7667680443901195,4.4515440828239035,1.8637126046605421,-0.2256084890274861,1.3275674269755584,0.43364725460652315
| 2,812
|
Transmembrane transport
| 40
| 187
| 2.632417
| 0.008478
|
Q9NS69,Q99595,O60830,Q70HW3,P21796,Q9C0H2,P45880,Q96ES6,Q8NHS3,P36543,P53985,O75964,Q8WTV0,Q9BZF1,Q8IXU6,P62942,Q5SR56,Q15629,Q9UHG3,O75844,Q6P4Q7,Q9UBX3,Q9H2D1,Q9Y4C2,O43865,P78417,Q14847,O43772,Q9Y619,P08183,P04062,Q06124,Q8NE01,Q9HD20,Q07820,P42858,P31751,Q06481,P47985,Q7L0J3
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
5,8,9,11,13,144,17,19,20,151,26,154,37,307,50,302,53,310,55,56,311,188,61,189,328,74,331,75,212,205,87,95,224,99,231,228,227,111,236,254
|
2071,1378,1268,2449,2018,516,720,639,75,1648,328,1429,9,2173,1325,2357,1604,1229,2219,2077,56,2468,2328,154,1548,2258,538,1385,1280,87,1030,1708,2221,2176,1709,2177,2224,2022,1710,205,917,2419,2331,2658,2623,1282,953,1434,1184,991,1332,2644,1187,1608,920,563,1659,13,372,1086,2702,2472,885,993,1660,816,1233,227,2574,1715,755,2540,1188,151,541,691,228,17,1336,236,2646,1662,1396,665,1192,1239,26,1502,2309,2542,1341,2527,2500,2716,2528,502,1294,1138,302,74,1725,2425,415,1243,1093,95,111,350,231,2045,454,1344,2692,894,331,2462,1675,764,310,1456,550,2400,932,1731,53,1835,2579,856,311,11,1009,254,1521,50,2615,2551,1523,224,530,20,393,2054,37,2109,2484,19,2511,974,1842,2771,2061,337,8,2512,858,2348,2117,2799,1797,307,144,2772,61,2440,1166,2375,1417,2165,99,5,1694,188,713,982,2009,55,1223,656,1749,409,866,636,1540,189,1953,212,908
|
-0.457189555658307,-0.08630127296868081,-0.031687014709587694,-0.7630370464216969,-0.4276312314054814,0.5552017244663052,0.3341012059117994,0.40895629462372546,2.358827559058653,-0.2256084890274861,0.9020494934900769,-0.11384263369455079,4.51024026447363,-0.5168492233508618,-0.05891660926003703,-0.6692630532977037,-0.19742355434165754,-0.004610885946918551,-0.5469546575117772,-0.457189555658307,2.533032514844444,-0.7946963348979321,-0.6383986218099443,1.5458110822803104,-0.16940208304943802,-0.5772466087129535,0.5311402316133299,-0.08630127296868081,-0.031687014709587694,2.24427219514418,0.10219020816314191,-0.25395864506177507,-0.5469546575117772,-0.5168492233508618,-0.25395864506177507,-0.5168492233508618,-0.5469546575117772,-0.4276312314054814,-0.25395864506177507,1.3072002040011301,0.1807547309326192,-0.7315799679422195,-0.6383986218099443,-1.1570110616486227,-1.0555468822980754,-0.031687014709587694,0.15470992714805706,-0.11384263369455079,0.022313356391112545,0.1285222344905635,-0.05891660926003703,-1.1229595856058519,0.022313356391112545,-0.19742355434165754,0.1807547309326192,0.5069552146823165,-0.2256084890274861,3.948903861103401,0.789268883456853,0.07571238201592677,-1.4020919554916431,-0.7946963348979321,0.2066580696947229,0.1285222344905635,-0.2256084890274861,0.2580459451927195,-0.004610885946918551,1.2248145512604927,-0.9561113158015919,-0.25395864506177507,0.3088845403658546,-0.8909116443167836,0.022313356391112545,1.565142433258028,0.5311402316133299,0.35918453124975014,1.2248145512604927,3.539634851198567,-0.05891660926003703,1.1830609814557924,-1.1229595856058519,-0.2256084890274861,-0.08630127296868081,0.38413580421459165,0.022313356391112545,-0.004610885946918551,3.3640668856918023,-0.1415423442786107,-0.6077272079458682,-0.8909116443167836,-0.05891660926003703,-0.858631173481535,-0.8265602308855787,-1.4743698115558657,-0.858631173481535,0.5791408457585902,-0.031687014709587694,0.04908726812999223,0.9903454141911546,2.3749525947181227,-0.25395864506177507,-0.7315799679422195,0.7202683829276397,-0.004610885946918551,0.07571238201592677,2.1096173622141015,1.899680038524244,0.8347092158473343,1.2248145512604927,-0.4276312314054814,0.6502352734037639,-0.05891660926003703,-1.3308378140240442,0.2066580696947229,0.9020494934900769,-0.7630370464216969,-0.2256084890274861,0.3088845403658546,0.9684284143189831,-0.11384263369455079,0.5311402316133299,-0.7003227426014513,0.1807547309326192,-0.25395864506177507,2.5793664440470323,-0.311161791776721,-0.9561113158015919,0.23242134673518783,0.9684284143189831,4.176415817828502,0.1285222344905635,1.1409252165655943,-0.1415423442786107,2.6403908305985557,-1.0221799869805437,-0.8909116443167836,-0.1415423442786107,1.245549991515183,0.5552017244663052,3.490212452974606,0.7663817253435458,-0.4276312314054814,3.0312962380643427,-0.457189555658307,-0.7946963348979321,3.539634851198567,-0.8265602308855787,0.15470992714805706,-0.311161791776721,-2.1342282062168807,-0.4276312314054814,0.8797108080344074,4.519940897786278,-0.8265602308855787,0.23242134673518783,-0.6383986218099443,-0.457189555658307,-3.9471181580065227,-0.28247580804102473,0.9903454141911546,1.6416545156496378,-2.1342282062168807,2.517478261676434,-0.7315799679422195,0.04908726812999223,-0.6692630532977037,-0.08630127296868081,-0.48692821008242365,2.0753063950252693,4.736858349607043,-0.2256084890274861,1.3881308939912163,0.35918453124975014,0.15470992714805706,-0.39825124132052653,2.548531725997088,0.022313356391112545,0.40895629462372546,-0.25395864506177507,0.7433818990772783,0.23242134673518783,0.43364725460652315,-0.1415423442786107,1.3881308939912163,-0.36904762138247893,1.3072002040011301,0.2066580696947229
| 2,812
|
Transport of small molecules
| 22
| 137
| 2.63088
| 0.008516
|
Q70HW3,P21796,Q9C0H2,P45880,P49721,P36543,P53985,P30519,Q8WTV0,Q9Y487,Q93050,P28072,Q9UBX3,P28074,Q99436,P09601,O15118,P08183,Q9HD20,P20618,P28070,P60900
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
11,13,144,17,18,151,26,30,37,41,170,45,188,70,199,79,82,205,99,102,110,120
|
514,2072,1481,2383,82,1271,2173,2219,519,347,1182,1704,1549,2258,2759,660,1030,1708,2221,1433,750,205,917,2633,79,520,2623,953,1434,2023,991,1332,1917,1187,1334,102,920,563,785,13,1970,1558,292,1288,1087,110,45,70,993,30,816,1233,755,2474,1036,487,1775,566,151,691,521,1131,17,845,314,18,2267,665,2634,26,2542,1341,2142,120,568,502,414,926,1666,1139,1983,666,1195,1670,1447,415,1449,525,731,2272,2692,2099,1987,1148,1149,1456,239,1731,2366,2579,11,2206,2615,1523,1461,530,393,37,2109,1527,170,2409,2771,1796,199,1531,2512,858,2348,977,144,1742,2772,2440,1166,99,188,1906,1223,1749,512,1643,745,636,41,1953,1176
|
0.5552017244663052,-0.457189555658307,-0.1415423442786107,-0.7003227426014513,2.326399504773361,-0.031687014709587694,-0.5168492233508618,-0.5469546575117772,0.5552017244663052,0.8347092158473343,0.022313356391112545,-0.25395864506177507,-0.16940208304943802,-0.5772466087129535,-1.9711219201568242,0.38413580421459165,0.10219020816314191,-0.25395864506177507,-0.5469546575117772,-0.11384263369455079,0.3088845403658546,1.3072002040011301,0.1807547309326192,-1.0891391456991428,2.342643329037244,0.5552017244663052,-1.0555468822980754,0.15470992714805706,-0.11384263369455079,-0.4276312314054814,0.1285222344905635,-0.05891660926003703,-0.36904762138247893,0.022313356391112545,-0.05891660926003703,2.005881846159429,0.1807547309326192,0.5069552146823165,0.2835332284224711,3.948903861103401,-0.39825124132052653,-0.16940208304943802,1.012159267293361,-0.031687014709587694,0.07571238201592677,1.899680038524244,2.759934875525814,2.4229764762472206,0.1285222344905635,3.247236697579701,0.2580459451927195,-0.004610885946918551,0.3088845403658546,-0.7946963348979321,0.10219020816314191,0.6029587324284209,-0.28247580804102473,0.5069552146823165,1.565142433258028,0.35918453124975014,0.5552017244663052,0.04908726812999223,3.539634851198567,0.23242134673518783,0.946407369350807,3.539634851198567,-0.5772466087129535,0.38413580421459165,-1.0891391456991428,3.3640668856918023,-0.8909116443167836,-0.05891660926003703,-0.48692821008242365,1.8274547643749006,0.5069552146823165,0.5791408457585902,0.7202683829276397,0.1807547309326192,-0.2256084890274861,0.04908726812999223,-0.39825124132052653,0.38413580421459165,0.022313356391112545,-0.2256084890274861,-0.11384263369455079,0.7202683829276397,-0.11384263369455079,0.5552017244663052,0.3341012059117994,-0.5772466087129535,-1.3308378140240442,-0.457189555658307,-0.39825124132052653,0.04908726812999223,0.04908726812999223,-0.11384263369455079,1.1830609814557924,-0.25395864506177507,-0.6692630532977037,-0.9561113158015919,4.176415817828502,-0.5168492233508618,-1.0221799869805437,-0.1415423442786107,-0.11384263369455079,0.5552017244663052,0.7663817253435458,3.0312962380643427,-0.457189555658307,-0.1415423442786107,1.4676530771754677,-0.7003227426014513,-2.1342282062168807,-0.28247580804102473,1.3478444644435112,-0.1415423442786107,-0.8265602308855787,0.23242134673518783,-0.6383986218099443,0.15470992714805706,1.6416545156496378,-0.25395864506177507,-2.1342282062168807,-0.7315799679422195,0.04908726812999223,2.0753063950252693,1.3881308939912163,-0.34001843888349026,0.022313356391112545,-0.25395864506177507,0.5791408457585902,-0.19742355434165754,0.3341012059117994,0.43364725460652315,2.8619031325793367,-0.36904762138247893,0.04908726812999223
| 2,812
|
Negative regulation of multicellular organismal process
| 22
| 94
| 2.628861
| 0.008567
|
P30536,Q9NQC3,P15260,P16989,P04083,Q9UIQ6,Q96G23,Q96FV9,O43823,Q92945,P31483,Q8WXW3,Q16850,Q8N0X7,Q4VCS5,P09601,P04062,Q06124,O14964,Q06481,P35080,Q9UBS4
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
0,266,132,136,269,25,27,434,166,178,424,325,69,209,332,79,87,95,225,111,360,380
|
225,1599,166,2356,2134,1182,2295,1548,1028,2469,1487,2770,87,269,1707,1866,1030,1387,2300,1765,79,1282,2454,132,1814,991,136,1187,1768,2180,565,0,816,2388,424,1290,360,2184,1291,2087,1611,1089,1443,2362,2560,620,1341,586,1400,2040,1296,1885,667,2425,1093,95,569,111,790,1827,1451,2504,2237,1571,671,69,332,447,2243,508,209,2780,1462,325,1211,178,434,27,830,1902,1795,2512,860,1166,2321,266,743,380,25,1374,1074,536,2353,2327
|
1.2248145512604927,-0.19742355434165754,1.4676530771754677,-0.6692630532977037,-0.48692821008242365,0.022313356391112545,-0.6077272079458682,-0.16940208304943802,0.10219020816314191,-0.7946963348979321,-0.1415423442786107,-2.1342282062168807,2.24427219514418,1.098400788944567,-0.25395864506177507,-0.34001843888349026,0.10219020816314191,-0.08630127296868081,-0.6077272079458682,-0.28247580804102473,2.342643329037244,-0.031687014709587694,-0.7630370464216969,1.679431285350743,-0.311161791776721,0.1285222344905635,1.6605823293503985,0.022313356391112545,-0.28247580804102473,-0.5168492233508618,0.5069552146823165,5.472379812321296,0.2580459451927195,-0.7003227426014513,0.6970401416277441,-0.031687014709587694,0.8120443818425275,-0.5168492233508618,-0.031687014709587694,-0.457189555658307,-0.19742355434165754,0.07571238201592677,-0.11384263369455079,-0.6692630532977037,-0.9234041685354025,0.43364725460652315,-0.05891660926003703,0.4826455052953858,-0.08630127296868081,-0.4276312314054814,-0.031687014709587694,-0.34001843888349026,0.38413580421459165,-0.7315799679422195,0.07571238201592677,2.1096173622141015,0.5069552146823165,1.899680038524244,0.2835332284224711,-0.311161791776721,-0.11384263369455079,-0.8265602308855787,-0.5469546575117772,-0.16940208304943802,0.38413580421459165,2.4547035837208413,0.9020494934900769,0.6736961261378334,-0.5469546575117772,0.5791408457585902,1.3072002040011301,-2.388988446943391,-0.11384263369455079,0.9242813695324721,0.022313356391112545,1.447902119529762,0.6970401416277441,3.3512432407507826,0.2580459451927195,-0.34001843888349026,-0.28247580804102473,-0.8265602308855787,0.23242134673518783,0.04908726812999223,-0.6077272079458682,1.119711996032066,0.3341012059117994,0.789268883456853,3.376851885313292,-0.05891660926003703,0.10219020816314191,0.5552017244663052,-0.6383986218099443,-0.6077272079458682
| 2,812
|
Glycerophospholipid biosynthesis
| 9
| 27
| 2.626435
| 0.008628
|
Q99829,Q8N2A8,Q8NF37,Q8IV08,Q9BZF1,Q9NPH0,Q8NCC3,Q99943,P35790
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
396,164,293,73,307,308,85,377,92
|
2656,1646,1380,1959,876,1186,92,921,1236,820,2392,1296,850,1153,73,164,2551,85,293,1463,407,396,377,307,308,1168,1755
|
-1.1570110616486227,-0.2256084890274861,-0.08630127296868081,-0.39825124132052653,0.2066580696947229,0.022313356391112545,2.1266741669465663,0.1807547309326192,-0.004610885946918551,0.2580459451927195,-0.7003227426014513,-0.031687014709587694,0.23242134673518783,0.04908726812999223,2.3910188320042183,1.4873187834566612,-0.8909116443167836,2.277306408278314,1.012159267293361,-0.11384263369455079,0.7433818990772783,0.7663817253435458,0.789268883456853,0.9903454141911546,0.9903454141911546,0.04908726812999223,-0.25395864506177507
| 2,812
|
Uch proteinases
| 10
| 43
| 2.625907
| 0.008642
|
P25788,P28074,Q99436,P20618,Q8NB78,P28072,P28070,P49721,P60900,P49720
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
292,70,199,102,105,45,110,18,120,314
|
514,2072,1481,2383,1757,1271,347,2701,1917,102,1970,1558,292,1288,1087,110,45,70,1775,1131,845,314,18,1928,2267,120,568,926,1666,1139,1449,2272,1148,1149,673,105,199,1531,633,512,1643,1752,1596
|
0.5552017244663052,-0.457189555658307,-0.1415423442786107,-0.7003227426014513,-0.28247580804102473,-0.031687014709587694,0.8347092158473343,-1.4020919554916431,-0.36904762138247893,2.005881846159429,-0.39825124132052653,-0.16940208304943802,1.012159267293361,-0.031687014709587694,0.07571238201592677,1.899680038524244,2.759934875525814,2.4229764762472206,-0.28247580804102473,0.04908726812999223,0.23242134673518783,0.946407369350807,3.539634851198567,-0.36904762138247893,-0.5772466087129535,1.8274547643749006,0.5069552146823165,0.1807547309326192,-0.2256084890274861,0.04908726812999223,-0.11384263369455079,-0.5772466087129535,0.04908726812999223,0.04908726812999223,0.38413580421459165,1.9353613048912393,1.3478444644435112,-0.1415423442786107,0.43364725460652315,0.5791408457585902,-0.19742355434165754,-0.25395864506177507,-0.16940208304943802
| 2,812
|
Regulation of runx2 expression and activity
| 9
| 41
| 2.625184
| 0.00866
|
P25788,P28074,Q99436,P20618,P28072,P28070,P49721,P60900,P49720
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
292,70,199,102,45,110,18,120,314
|
514,2072,1481,2383,1271,347,1917,102,1970,1558,292,1288,1087,110,45,70,1775,1443,1131,845,314,18,2267,120,568,926,1666,1139,666,1449,2272,2546,1987,1571,1148,1149,199,1531,512,1538,1643
|
0.5552017244663052,-0.457189555658307,-0.1415423442786107,-0.7003227426014513,-0.031687014709587694,0.8347092158473343,-0.36904762138247893,2.005881846159429,-0.39825124132052653,-0.16940208304943802,1.012159267293361,-0.031687014709587694,0.07571238201592677,1.899680038524244,2.759934875525814,2.4229764762472206,-0.28247580804102473,-0.11384263369455079,0.04908726812999223,0.23242134673518783,0.946407369350807,3.539634851198567,-0.5772466087129535,1.8274547643749006,0.5069552146823165,0.1807547309326192,-0.2256084890274861,0.04908726812999223,0.38413580421459165,-0.11384263369455079,-0.5772466087129535,-0.8909116443167836,-0.39825124132052653,-0.16940208304943802,0.04908726812999223,0.04908726812999223,1.3478444644435112,-0.1415423442786107,0.5791408457585902,-0.1415423442786107,-0.19742355434165754
| 2,812
|
Predicted secreted proteins
| 18
| 50
| 2.619947
| 0.008794
|
O60888,Q9HB40,O00584,Q9UMX5,O75718,Q9Y287,P14174,Q8WXW3,Q15165,Q9BTY2,P04083,P43490,Q8WUJ1,Q08380,Q6P179,P80303,Q8IW92,P07858
|
Functions
|
Protein Atlas Protein class
|
protein_atlas_protein_class
|
35,36,159,38,259,174,260,325,103,143,269,49,81,238,279,59,94,32
|
159,35,259,2295,2587,660,269,1488,2224,32,2300,260,1085,469,2606,2085,2797,49,1444,2090,1193,414,59,2706,1622,543,790,238,2336,2148,2594,103,279,1837,94,2369,2780,81,1209,325,2058,2564,143,1639,326,36,438,38,174,1753
|
1.4873187834566612,3.127113381098637,1.119711996032066,-0.6077272079458682,-0.9890357013357498,0.38413580421459165,1.098400788944567,-0.1415423442786107,-0.5469546575117772,3.16753088514317,-0.6077272079458682,1.119711996032066,0.07571238201592677,0.6266565061101952,-1.0221799869805437,-0.457189555658307,-3.774897071094452,2.655514539093404,-0.11384263369455079,-0.457189555658307,0.022313356391112545,0.7202683829276397,2.533032514844444,-1.4381012368155113,-0.19742355434165754,0.5311402316133299,0.2835332284224711,1.1830609814557924,-0.6383986218099443,-0.48692821008242365,-0.9890357013357498,1.988355693566339,1.0769907617339176,-0.311161791776721,2.1266741669465663,-0.6692630532977037,-2.388988446943391,2.342643329037244,0.022313356391112545,0.9242813695324721,-0.4276312314054814,-0.9234041685354025,1.6416545156496378,-0.19742355434165754,0.9242813695324721,3.0588916001916124,0.6970401416277441,3.0035225327511377,1.4676530771754677,-0.25395864506177507
| 2,812
|
Abnormality of the spleen
| 21
| 104
| 2.61825
| 0.008838
|
P15260,P14174,Q15392,P21964,O96028,P08236,P16278,P01889,P10619,O15118,P54802,Q14108,P04062,Q06124,Q14739,P07602,Q9Y285,P28070,Q15437,Q15904,O14936
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
132,260,10,270,147,148,161,167,67,82,83,84,87,95,232,101,106,110,114,239,119
|
1702,1269,2073,119,82,805,1862,1325,987,1431,2258,1550,147,2298,167,1487,87,384,2452,1707,1488,2222,101,2080,148,1183,301,67,2623,724,1490,1282,2689,260,132,811,161,2643,1918,920,270,2724,2180,110,993,1770,1393,1088,1292,2789,1877,1443,585,692,664,1565,1397,757,1567,1780,83,925,2235,414,2613,95,525,526,1346,2692,1304,84,232,646,10,114,2399,239,1404,341,1010,1894,2055,1256,2245,1211,650,2408,706,1902,1843,2004,2772,2442,1071,438,1020,1694,656,836,106,1423,1856,1480
|
-0.25395864506177507,-0.031687014709587694,-0.457189555658307,1.8274547643749006,2.326399504773361,0.2580459451927195,-0.34001843888349026,-0.05891660926003703,0.1285222344905635,-0.11384263369455079,-0.5772466087129535,-0.16940208304943802,1.6035598788121985,-0.6077272079458682,1.4676530771754677,-0.1415423442786107,2.24427219514418,0.7663817253435458,-0.7630370464216969,-0.25395864506177507,-0.1415423442786107,-0.5469546575117772,2.0233395056563532,-0.457189555658307,1.5843918203314797,0.022313356391112545,0.9903454141911546,2.4704816361758035,-1.0555468822980754,0.3341012059117994,-0.1415423442786107,-0.031687014709587694,-1.29558638215688,1.119711996032066,1.679431285350743,0.2580459451927195,1.4873187834566612,-1.1229595856058519,-0.36904762138247893,0.1807547309326192,1.098400788944567,-1.54769869262779,-0.5168492233508618,1.899680038524244,0.1285222344905635,-0.28247580804102473,-0.08630127296868081,0.07571238201592677,-0.031687014709587694,-2.749330655939741,-0.34001843888349026,-0.11384263369455079,0.4826455052953858,0.35918453124975014,0.38413580421459165,-0.16940208304943802,-0.08630127296868081,0.3088845403658546,-0.16940208304943802,-0.28247580804102473,2.310095682444116,0.1807547309326192,-0.5469546575117772,0.7202683829276397,-1.0221799869805437,2.1096173622141015,0.5552017244663052,0.5552017244663052,-0.05891660926003703,-1.3308378140240442,-0.031687014709587694,2.277306408278314,1.2248145512604927,0.40895629462372546,4.4515440828239035,1.8637126046605421,-0.7003227426014513,1.1830609814557924,-0.08630127296868081,0.8572643679612094,0.1285222344905635,-0.34001843888349026,-0.4276312314054814,-0.004610885946918551,-0.5469546575117772,0.022313356391112545,0.40895629462372546,-0.7003227426014513,0.35918453124975014,-0.34001843888349026,-0.311161791776721,-0.39825124132052653,-2.1342282062168807,-0.7315799679422195,0.10219020816314191,0.6970401416277441,0.1285222344905635,-0.2256084890274861,0.40895629462372546,0.2580459451927195,1.9353613048912393,-0.08630127296868081,-0.311161791776721,-0.11384263369455079
| 2,812
|
Proteasome beta-type subunit, conserved site [IPR016050]
| 6
| 8
| 2.614441
| 0.008937
|
P28074,P20618,Q99436,P28072,P28070,P49721
|
Sequence
|
InterPro Conserved site
|
interpro_conserved_site
|
70,102,199,45,110,18
|
102,1288,110,45,70,314,18,199
|
2.005881846159429,-0.031687014709587694,1.899680038524244,2.759934875525814,2.4229764762472206,0.946407369350807,3.539634851198567,1.3478444644435112
| 2,812
|
Threonine type endopeptidase activity
| 6
| 8
| 2.614441
| 0.008937
|
P28074,P20618,Q99436,P28072,P28070,P49721
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
70,102,199,45,110,18
|
102,1288,110,45,70,314,18,199
|
2.005881846159429,-0.031687014709587694,1.899680038524244,2.759934875525814,2.4229764762472206,0.946407369350807,3.539634851198567,1.3478444644435112
| 2,812
|
Threonine type peptidase activity
| 6
| 8
| 2.614441
| 0.008937
|
P28074,P20618,Q99436,P28072,P28070,P49721
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
70,102,199,45,110,18
|
102,1288,110,45,70,314,18,199
|
2.005881846159429,-0.031687014709587694,1.899680038524244,2.759934875525814,2.4229764762472206,0.946407369350807,3.539634851198567,1.3478444644435112
| 2,812
|
Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen
| 8
| 24
| 2.605837
| 0.009165
|
Q32P28,Q16850,Q8NB78,P29375,P09601,P30519,Q15800,P13674
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
96,69,105,271,79,30,152,156
|
2129,1545,2384,2521,750,79,156,583,271,30,1137,1726,731,506,152,69,96,1732,1733,1679,105,298,420,2676
|
-0.48692821008242365,-0.16940208304943802,-0.7003227426014513,-0.858631173481535,0.3088845403658546,2.342643329037244,1.5263971248405028,0.4826455052953858,1.098400788944567,3.247236697579701,0.04908726812999223,-0.25395864506177507,0.3341012059117994,0.5791408457585902,1.565142433258028,2.4547035837208413,2.0924949265029182,-0.25395864506177507,-0.25395864506177507,-0.2256084890274861,1.9353613048912393,1.012159267293361,0.7202683829276397,-1.1912964858988957
| 2,812
|
Mitochondrial transport
| 12
| 77
| 2.603516
| 0.009227
|
P30536,P30419,Q9Y512,Q9NS69,Q99595,O60830,O43772,P45880,O14737,O75964,Q5JRX3,Q9UBX3
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
0,98,165,5,8,9,75,17,175,154,157,188
|
1267,175,516,720,75,9,2133,2219,2328,154,1548,1654,1706,538,1385,1707,2221,2177,808,1656,2658,953,1186,372,1086,2702,1660,98,0,2029,1188,2140,17,2646,1133,2089,1192,386,2527,2500,2545,525,668,2197,670,764,1785,932,850,157,1835,1307,1459,768,235,531,2113,1633,633,8,858,2631,2761,1417,5,1073,2704,1948,188,714,656,1749,2127,1854,536,165,2688
|
-0.031687014709587694,1.447902119529762,0.5552017244663052,0.3341012059117994,2.358827559058653,4.51024026447363,-0.48692821008242365,-0.5469546575117772,-0.6383986218099443,1.5458110822803104,-0.16940208304943802,-0.2256084890274861,-0.25395864506177507,0.5311402316133299,-0.08630127296868081,-0.25395864506177507,-0.5469546575117772,-0.5168492233508618,0.2580459451927195,-0.2256084890274861,-1.1570110616486227,0.15470992714805706,0.022313356391112545,0.789268883456853,0.07571238201592677,-1.4020919554916431,-0.2256084890274861,2.0753063950252693,5.472379812321296,-0.4276312314054814,0.022313356391112545,-0.48692821008242365,3.539634851198567,-1.1229595856058519,0.04908726812999223,-0.457189555658307,0.022313356391112545,0.7663817253435458,-0.858631173481535,-0.8265602308855787,-0.8909116443167836,0.5552017244663052,0.38413580421459165,-0.5168492233508618,0.38413580421459165,0.3088845403658546,-0.28247580804102473,0.1807547309326192,0.23242134673518783,1.5263971248405028,-0.311161791776721,-0.031687014709587694,-0.11384263369455079,0.3088845403658546,1.2039851426447223,0.5552017244663052,-0.457189555658307,-0.19742355434165754,0.43364725460652315,4.519940897786278,0.23242134673518783,-1.0555468822980754,-1.9711219201568242,-0.08630127296868081,4.736858349607043,0.10219020816314191,-1.4020919554916431,-0.36904762138247893,1.3881308939912163,0.35918453124975014,0.40895629462372546,-0.25395864506177507,-0.457189555658307,-0.311161791776721,0.5552017244663052,1.4873187834566612,-1.260581097169132
| 2,812
|
Blindness
| 14
| 68
| 2.582132
| 0.009819
|
P16278,Q96CU9,P21912,Q15555,O43676,P50897,P07602,P01889,Q969G3,O43505,O75306,Q8NHS3,P06865,Q9Y6M9
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
161,4,196,197,39,68,101,167,201,47,115,20,150,258
|
2257,1267,1759,2493,47,39,1602,2357,115,2536,949,1327,1705,875,2469,167,451,2330,150,101,2080,2470,161,251,2572,1768,196,2305,1919,2473,1441,1291,2682,1037,585,887,1880,68,1040,2037,1726,1508,1301,1989,2595,197,855,2243,1737,1058,475,20,1255,1683,201,4,2158,633,2159,2630,2566,776,438,1020,2411,2489,1539,258
|
-0.5772466087129535,-0.031687014709587694,-0.28247580804102473,-0.8265602308855787,2.7303554016709937,2.933293974683996,-0.19742355434165754,-0.6692630532977037,1.8456202538155837,-0.8909116443167836,0.15470992714805706,-0.05891660926003703,-0.25395864506177507,0.2066580696947229,-0.7946963348979321,1.4676530771754677,0.6502352734037639,-0.6383986218099443,1.565142433258028,2.0233395056563532,-0.457189555658307,-0.7946963348979321,1.4873187834566612,1.1409252165655943,-0.9561113158015919,-0.28247580804102473,1.3478444644435112,-0.6077272079458682,-0.36904762138247893,-0.7946963348979321,-0.11384263369455079,-0.031687014709587694,-1.260581097169132,0.10219020816314191,0.4826455052953858,0.2066580696947229,-0.34001843888349026,2.4547035837208413,0.10219020816314191,-0.4276312314054814,-0.25395864506177507,-0.1415423442786107,-0.031687014709587694,-0.39825124132052653,-0.9890357013357498,1.3478444644435112,0.23242134673518783,-0.5469546575117772,-0.25395864506177507,0.10219020816314191,0.6266565061101952,3.490212452974606,-0.004610885946918551,-0.2256084890274861,1.3275674269755584,4.773418117753822,-0.48692821008242365,0.43364725460652315,-0.48692821008242365,-1.0555468822980754,-0.9234041685354025,0.3088845403658546,0.6970401416277441,0.1285222344905635,-0.7003227426014513,-0.7946963348979321,-0.1415423442786107,1.1409252165655943
| 2,812
|
Rna stabilization
| 13
| 28
| 2.579978
| 0.009881
|
Q14103,Q16539,O60506,Q9H074,P11940,P67809,P98175,P16989,Q92615,P35637,Q08J23,Q14011,Q92804
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
351,550,194,264,412,229,230,136,589,141,277,93,65
|
194,1862,1650,1550,809,412,136,141,229,230,694,1095,277,1450,846,93,351,1574,550,602,2207,589,65,264,2711,940,1264,1076
|
1.3478444644435112,-0.34001843888349026,-0.2256084890274861,-0.16940208304943802,0.2580459451927195,0.7202683829276397,1.6605823293503985,1.6416545156496378,1.2248145512604927,1.2248145512604927,0.35918453124975014,0.07571238201592677,1.0769907617339176,-0.11384263369455079,0.23242134673518783,2.1266741669465663,0.8347092158473343,-0.16940208304943802,0.5311402316133299,0.45820991892635715,-0.5168492233508618,0.4826455052953858,2.486203187179412,1.119711996032066,-1.4381012368155113,0.1807547309326192,-0.004610885946918551,0.10219020816314191
| 2,812
|
Interferon signaling
| 17
| 61
| 2.579907
| 0.009883
|
O15344,P55735,O00505,P10321,Q9BW27,P15260,Q9BTX1,Q99567,O00629,P01889,P52294,Q8NFH4,P19474,P57740,Q12769,Q06124,P04439
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
440,129,31,312,466,132,494,533,42,167,43,240,116,284,505,95,160
|
31,42,440,910,2415,1649,950,167,160,312,1388,132,1389,2644,116,1185,1659,564,1875,1235,1442,1443,1663,960,923,43,2233,925,129,284,1883,2093,2270,2395,961,95,505,1096,1986,2099,1831,547,1051,1204,1997,1578,971,1898,240,1793,1311,1413,2463,533,494,2119,466,1744,1373,1856,1425
|
3.16753088514317,2.803929621091696,0.6736961261378334,0.1807547309326192,-0.7315799679422195,-0.2256084890274861,0.15470992714805706,1.4676530771754677,1.4873187834566612,0.946407369350807,-0.08630127296868081,1.679431285350743,-0.08630127296868081,-1.1229595856058519,1.8456202538155837,0.022313356391112545,-0.2256084890274861,0.5069552146823165,-0.34001843888349026,-0.004610885946918551,-0.11384263369455079,-0.11384263369455079,-0.2256084890274861,0.15470992714805706,0.1807547309326192,2.789314221988835,-0.5469546575117772,0.1807547309326192,1.7168950201979138,1.0554810704738096,-0.34001843888349026,-0.457189555658307,-0.5772466087129535,-0.7003227426014513,0.15470992714805706,2.1096173622141015,0.5791408457585902,0.07571238201592677,-0.39825124132052653,-0.457189555658307,-0.311161791776721,0.5311402316133299,0.10219020816314191,0.022313356391112545,-0.39825124132052653,-0.16940208304943802,0.15470992714805706,-0.34001843888349026,1.1830609814557924,-0.28247580804102473,-0.031687014709587694,-0.08630127296868081,-0.7630370464216969,0.5552017244663052,0.6029587324284209,-0.457189555658307,0.6502352734037639,-0.25395864506177507,-0.05891660926003703,-0.311161791776721,-0.08630127296868081
| 2,812
|
Pten regulation
| 20
| 59
| 2.579693
| 0.009889
|
O00231,P49721,Q15022,P25788,P28072,P49720,P61289,P28074,Q99436,Q8IXK0,Q9HCE1,O75832,Q92769,P31751,P20618,P28070,O95983,Q9UL46,P60900,P42345
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
514,18,549,292,45,314,568,70,199,458,609,347,492,227,102,110,358,512,120,501
|
514,2072,1481,2383,1271,2384,347,1762,358,1707,1917,1186,102,1970,1558,292,1288,1087,110,45,70,1769,227,1775,501,1131,845,314,18,2267,120,568,926,1666,1139,1296,1449,2272,1830,1198,1147,1148,1149,549,2667,1792,458,1313,492,738,199,1531,633,2672,609,1589,512,1538,1643
|
0.5552017244663052,-0.457189555658307,-0.1415423442786107,-0.7003227426014513,-0.031687014709587694,-0.7003227426014513,0.8347092158473343,-0.28247580804102473,0.8120443818425275,-0.25395864506177507,-0.36904762138247893,0.022313356391112545,2.005881846159429,-0.39825124132052653,-0.16940208304943802,1.012159267293361,-0.031687014709587694,0.07571238201592677,1.899680038524244,2.759934875525814,2.4229764762472206,-0.28247580804102473,1.2248145512604927,-0.28247580804102473,0.5791408457585902,0.04908726812999223,0.23242134673518783,0.946407369350807,3.539634851198567,-0.5772466087129535,1.8274547643749006,0.5069552146823165,0.1807547309326192,-0.2256084890274861,0.04908726812999223,-0.031687014709587694,-0.11384263369455079,-0.5772466087129535,-0.311161791776721,0.022313356391112545,0.04908726812999223,0.04908726812999223,0.04908726812999223,0.5311402316133299,-1.1912964858988957,-0.28247580804102473,0.6502352734037639,-0.031687014709587694,0.6029587324284209,0.3341012059117994,1.3478444644435112,-0.1415423442786107,0.43364725460652315,-1.1912964858988957,0.45820991892635715,-0.16940208304943802,0.5791408457585902,-0.1415423442786107,-0.19742355434165754
| 2,812
|
Scf skp2 mediated degradation of p27 p21
| 9
| 39
| 2.577618
| 0.009948
|
P25788,P28074,Q99436,P20618,P28072,P28070,P49721,P60900,P49720
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
292,70,199,102,45,110,18,120,314
|
514,2072,1481,2383,1271,347,725,1917,102,955,1970,1558,292,1288,1087,110,45,70,1775,1131,845,314,18,2267,120,568,926,1666,1139,666,1449,2272,2546,1987,1149,199,1531,512,1643
|
0.5552017244663052,-0.457189555658307,-0.1415423442786107,-0.7003227426014513,-0.031687014709587694,0.8347092158473343,0.3341012059117994,-0.36904762138247893,2.005881846159429,0.15470992714805706,-0.39825124132052653,-0.16940208304943802,1.012159267293361,-0.031687014709587694,0.07571238201592677,1.899680038524244,2.759934875525814,2.4229764762472206,-0.28247580804102473,0.04908726812999223,0.23242134673518783,0.946407369350807,3.539634851198567,-0.5772466087129535,1.8274547643749006,0.5069552146823165,0.1807547309326192,-0.2256084890274861,0.04908726812999223,0.38413580421459165,-0.11384263369455079,-0.5772466087129535,-0.8909116443167836,-0.39825124132052653,0.04908726812999223,1.3478444644435112,-0.1415423442786107,0.5791408457585902,-0.19742355434165754
| 2,812
|
Orc1 removal from chromatin
| 10
| 49
| 2.570456
| 0.010156
|
P25788,P28074,Q99436,P20618,P28072,P28070,Q9Y619,P49721,P60900,P49720
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
292,70,199,102,45,110,212,18,120,314
|
514,2072,1481,2383,1271,2075,347,1917,102,955,1873,1970,1558,292,1288,1087,110,45,70,1393,1661,1772,1775,1131,845,314,18,996,2267,120,568,926,1666,1139,666,1449,2272,2546,760,1987,1246,1148,1149,199,1531,534,512,1643,212
|
0.5552017244663052,-0.457189555658307,-0.1415423442786107,-0.7003227426014513,-0.031687014709587694,-0.457189555658307,0.8347092158473343,-0.36904762138247893,2.005881846159429,0.15470992714805706,-0.34001843888349026,-0.39825124132052653,-0.16940208304943802,1.012159267293361,-0.031687014709587694,0.07571238201592677,1.899680038524244,2.759934875525814,2.4229764762472206,-0.08630127296868081,-0.2256084890274861,-0.28247580804102473,-0.28247580804102473,0.04908726812999223,0.23242134673518783,0.946407369350807,3.539634851198567,0.1285222344905635,-0.5772466087129535,1.8274547643749006,0.5069552146823165,0.1807547309326192,-0.2256084890274861,0.04908726812999223,0.38413580421459165,-0.11384263369455079,-0.5772466087129535,-0.8909116443167836,0.3088845403658546,-0.39825124132052653,-0.004610885946918551,0.04908726812999223,0.04908726812999223,1.3478444644435112,-0.1415423442786107,0.5552017244663052,0.5791408457585902,-0.19742355434165754,1.3072002040011301
| 2,812
|
Tcr signaling
| 9
| 41
| 2.566674
| 0.010268
|
P25788,P28074,Q99436,P20618,P28072,P28070,P49721,P60900,P49720
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
292,70,199,102,45,110,18,120,314
|
514,2072,1481,2383,1271,347,1917,2644,102,1970,1558,292,1288,1087,110,45,70,1775,1089,1131,845,314,18,2267,120,568,926,1666,1139,666,1449,1401,2272,1987,1148,1149,1838,199,1531,512,1643
|
0.5552017244663052,-0.457189555658307,-0.1415423442786107,-0.7003227426014513,-0.031687014709587694,0.8347092158473343,-0.36904762138247893,-1.1229595856058519,2.005881846159429,-0.39825124132052653,-0.16940208304943802,1.012159267293361,-0.031687014709587694,0.07571238201592677,1.899680038524244,2.759934875525814,2.4229764762472206,-0.28247580804102473,0.07571238201592677,0.04908726812999223,0.23242134673518783,0.946407369350807,3.539634851198567,-0.5772466087129535,1.8274547643749006,0.5069552146823165,0.1807547309326192,-0.2256084890274861,0.04908726812999223,0.38413580421459165,-0.11384263369455079,-0.08630127296868081,-0.5772466087129535,-0.39825124132052653,0.04908726812999223,0.04908726812999223,-0.311161791776721,1.3478444644435112,-0.1415423442786107,0.5791408457585902,-0.19742355434165754
| 2,812
|
Negative regulation of mrna catabolic process
| 11
| 27
| 2.557201
| 0.010552
|
Q14103,P67809,O60506,Q9H074,Q06787,P98175,P16989,P35637,Q99729,Q14011,Q92804
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
351,229,194,264,350,230,136,141,343,93,65
|
2735,194,1650,809,412,136,141,229,230,694,350,1095,1450,846,93,351,2397,1574,550,602,2207,589,65,343,264,1264,1076
|
-1.6597250820929819,1.3478444644435112,-0.2256084890274861,0.2580459451927195,0.7202683829276397,1.6605823293503985,1.6416545156496378,1.2248145512604927,1.2248145512604927,0.35918453124975014,0.8347092158473343,0.07571238201592677,-0.11384263369455079,0.23242134673518783,2.1266741669465663,0.8347092158473343,-0.7003227426014513,-0.16940208304943802,0.5311402316133299,0.45820991892635715,-0.5168492233508618,0.4826455052953858,2.486203187179412,0.8572643679612094,1.119711996032066,-0.004610885946918551,0.10219020816314191
| 2,812
|
Signaling by hedgehog
| 11
| 51
| 2.553065
| 0.010678
|
P25788,P28074,Q99436,P68371,P20618,P28072,P28070,P49721,Q9BVA1,P60900,P49720
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
292,70,199,261,102,45,110,18,248,120,314
|
514,2072,1481,2383,1271,347,750,520,2023,1332,1917,102,1970,1558,292,1288,1087,110,45,70,1775,1131,845,786,314,18,2267,2142,120,568,926,1666,1139,666,261,1449,2272,1987,2100,1148,1149,1677,2405,1902,199,1531,682,248,1742,512,1643
|
0.5552017244663052,-0.457189555658307,-0.1415423442786107,-0.7003227426014513,-0.031687014709587694,0.8347092158473343,0.3088845403658546,0.5552017244663052,-0.4276312314054814,-0.05891660926003703,-0.36904762138247893,2.005881846159429,-0.39825124132052653,-0.16940208304943802,1.012159267293361,-0.031687014709587694,0.07571238201592677,1.899680038524244,2.759934875525814,2.4229764762472206,-0.28247580804102473,0.04908726812999223,0.23242134673518783,0.2835332284224711,0.946407369350807,3.539634851198567,-0.5772466087129535,-0.48692821008242365,1.8274547643749006,0.5069552146823165,0.1807547309326192,-0.2256084890274861,0.04908726812999223,0.38413580421459165,1.119711996032066,-0.11384263369455079,-0.5772466087129535,-0.39825124132052653,-0.457189555658307,0.04908726812999223,0.04908726812999223,-0.2256084890274861,-0.7003227426014513,-0.34001843888349026,1.3478444644435112,-0.1415423442786107,0.38413580421459165,1.1620412739234138,-0.25395864506177507,0.5791408457585902,-0.19742355434165754
| 2,812
|
Ascites
| 9
| 23
| 2.549634
| 0.010784
|
P61916,Q01844,Q14739,O15118,P08236,P10644,Q14108,P04062,Q00059
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
414,349,232,82,148,520,84,87,503
|
82,1760,658,1278,87,148,520,1492,2643,1397,414,1446,1298,503,349,569,1346,84,232,1005,1210,1586,1754
|
2.326399504773361,-0.28247580804102473,0.38413580421459165,-0.031687014709587694,2.24427219514418,1.5843918203314797,0.5552017244663052,-0.1415423442786107,-1.1229595856058519,-0.08630127296868081,0.7202683829276397,-0.11384263369455079,-0.031687014709587694,0.5791408457585902,0.8347092158473343,0.5069552146823165,-0.05891660926003703,2.277306408278314,1.2248145512604927,0.1285222344905635,0.022313356391112545,-0.16940208304943802,-0.25395864506177507
| 2,812
|
Hyperlipidemia
| 12
| 25
| 2.542552
| 0.011005
|
Q92734,P50402,Q9UJS0,P31751,Q9Y285,O95470,P06280,P35573,P28070,P23786,O75844,P22830
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
532,413,656,227,106,537,168,361,110,372,56,618
|
2130,639,2133,56,537,1487,168,916,618,372,110,2086,227,361,1133,413,1780,1783,1525,532,1315,2158,1216,656,106
|
-0.48692821008242365,0.40895629462372546,-0.48692821008242365,2.533032514844444,0.5311402316133299,-0.1415423442786107,1.4676530771754677,0.1807547309326192,0.43364725460652315,0.789268883456853,1.899680038524244,-0.457189555658307,1.2248145512604927,0.8120443818425275,0.04908726812999223,0.7202683829276397,-0.28247580804102473,-0.28247580804102473,-0.1415423442786107,0.5552017244663052,-0.031687014709587694,-0.48692821008242365,0.022313356391112545,0.40895629462372546,1.9353613048912393
| 2,812
|
Myoclonus
| 13
| 76
| 2.542079
| 0.01102
|
Q96CU9,P50897,O14773,P07602,P42858,Q969G3,Q14108,O75503,P00374,P04062,O14936,Q9UBX3,Q7L7X3
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
4,68,100,101,228,201,84,21,245,87,119,188,221
|
2449,1910,2017,100,119,1324,870,21,952,1385,245,1280,451,87,784,101,2623,1184,1185,920,338,1440,2473,1875,1235,691,228,663,822,68,2560,758,925,1091,1296,1299,1447,252,643,789,695,1827,525,2098,1508,1346,1145,84,1889,669,1403,2433,221,1010,933,201,4,2409,1684,1841,1795,740,633,1467,2790,1419,1168,591,1020,188,2254,2675,536,2353,1953,1954
|
-0.7630370464216969,-0.36904762138247893,-0.4276312314054814,2.0407291615321252,1.8274547643749006,-0.05891660926003703,0.2066580696947229,3.4527621477763786,0.15470992714805706,-0.08630127296868081,1.1620412739234138,-0.031687014709587694,0.6502352734037639,2.24427219514418,0.2835332284224711,2.0233395056563532,-1.0555468822980754,0.022313356391112545,0.022313356391112545,0.1807547309326192,0.8572643679612094,-0.11384263369455079,-0.7946963348979321,-0.34001843888349026,-0.004610885946918551,0.35918453124975014,1.2248145512604927,0.38413580421459165,0.2580459451927195,2.4547035837208413,-0.9234041685354025,0.3088845403658546,0.1807547309326192,0.07571238201592677,-0.031687014709587694,-0.031687014709587694,-0.11384263369455079,1.1409252165655943,0.40895629462372546,0.2835332284224711,0.35918453124975014,-0.311161791776721,0.5552017244663052,-0.457189555658307,-0.1415423442786107,-0.05891660926003703,0.04908726812999223,2.277306408278314,-0.34001843888349026,0.38413580421459165,-0.08630127296868081,-0.7315799679422195,1.2661922382132038,0.1285222344905635,0.1807547309326192,1.3275674269755584,4.773418117753822,-0.7003227426014513,-0.2256084890274861,-0.311161791776721,-0.28247580804102473,0.3341012059117994,0.43364725460652315,-0.11384263369455079,-2.749330655939741,-0.08630127296868081,0.04908726812999223,0.4826455052953858,0.1285222344905635,1.3881308939912163,-0.5469546575117772,-1.1912964858988957,0.5552017244663052,-0.6383986218099443,-0.36904762138247893,-0.36904762138247893
| 2,812
|
Regulation of response to external stimulus
| 41
| 117
| 2.537856
| 0.011153
|
P14174,Q9UKG1,P04083,P43243,Q96G23,P04439,Q16543,Q16539,Q9UMX5,P01889,Q9NZ08,Q14671,O75844,P80303,Q53EL6,P10586,O75179,Q9NUD5,P58107,Q9UNH7,P04062,Q96ST3,Q9NUQ9,Q96KB5,Q06124,P30419,O00429,Q9H000,Q8IXJ6,Q02750,Q99496,Q06481,P28070,P04792,O94992,P19474,Q9BVA1,P60900,O14936,O43657,Q96PK6
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
260,409,269,522,27,160,289,550,38,167,438,428,56,59,447,562,195,203,586,613,87,478,89,477,95,98,594,367,508,362,633,111,110,483,482,116,248,120,119,370,256
|
594,119,948,370,1761,195,2134,2521,56,2295,1548,1955,482,167,87,269,160,483,808,1553,1387,2300,562,990,2571,2138,260,1389,2644,116,1659,1495,1970,2085,2180,110,1769,98,1290,755,1611,1443,522,2459,1563,2035,620,2091,1341,925,586,120,2611,1400,787,667,59,362,95,111,790,1095,2044,2765,1401,2692,1570,2547,428,2102,1674,1202,672,550,289,1731,447,2315,1999,736,508,1156,1207,770,1462,1257,2156,1211,27,1902,477,256,1633,478,633,2061,2160,248,2410,367,1166,203,89,1641,1263,1849,438,1264,2168,2698,744,409,38,613,1074,1856,1700
|
0.45820991892635715,1.8274547643749006,0.15470992714805706,0.789268883456853,-0.28247580804102473,1.3478444644435112,-0.48692821008242365,-0.858631173481535,2.533032514844444,-0.6077272079458682,-0.16940208304943802,-0.39825124132052653,0.6029587324284209,1.4676530771754677,2.24427219514418,1.098400788944567,1.4873187834566612,0.6029587324284209,0.2580459451927195,-0.16940208304943802,-0.08630127296868081,-0.6077272079458682,0.5069552146823165,0.1285222344905635,-0.9561113158015919,-0.48692821008242365,1.119711996032066,-0.08630127296868081,-1.1229595856058519,1.8456202538155837,-0.2256084890274861,-0.1415423442786107,-0.39825124132052653,-0.457189555658307,-0.5168492233508618,1.899680038524244,-0.28247580804102473,2.0753063950252693,-0.031687014709587694,0.3088845403658546,-0.19742355434165754,-0.11384263369455079,0.5552017244663052,-0.7630370464216969,-0.16940208304943802,-0.4276312314054814,0.43364725460652315,-0.457189555658307,-0.05891660926003703,0.1807547309326192,0.4826455052953858,1.8274547643749006,-1.0221799869805437,-0.08630127296868081,0.2835332284224711,0.38413580421459165,2.533032514844444,0.8120443818425275,2.1096173622141015,1.899680038524244,0.2835332284224711,0.07571238201592677,-0.4276312314054814,-2.05202791259183,-0.08630127296868081,-1.3308378140240442,-0.16940208304943802,-0.8909116443167836,0.6970401416277441,-0.457189555658307,-0.2256084890274861,0.022313356391112545,0.38413580421459165,0.5311402316133299,1.0338708607112133,-0.25395864506177507,0.6736961261378334,-0.6077272079458682,-0.39825124132052653,0.3341012059117994,0.5791408457585902,0.04908726812999223,0.022313356391112545,0.3088845403658546,-0.11384263369455079,-0.004610885946918551,-0.48692821008242365,0.022313356391112545,3.3512432407507826,-0.34001843888349026,0.6266565061101952,1.1409252165655943,-0.19742355434165754,0.6266565061101952,0.43364725460652315,-0.4276312314054814,-0.48692821008242365,1.1620412739234138,-0.7003227426014513,0.8120443818425275,0.04908726812999223,1.3275674269755584,2.1942542072619107,-0.19742355434165754,-0.004610885946918551,-0.311161791776721,0.6970401416277441,-0.004610885946918551,-0.48692821008242365,-1.3663385868789217,0.3341012059117994,0.7433818990772783,3.0035225327511377,0.45820991892635715,0.10219020816314191,-0.311161791776721,-0.2256084890274861
| 2,812
|
Ion transmembrane transporter activity
| 15
| 91
| 2.534583
| 0.011258
|
Q9HD20,O75964,Q9Y487,Q70HW3,Q93050,P21796,O43772,Q9C0H2,Q9Y619,P45880,Q96ES6,P36543,P53985,Q9UBX3,Q9H2D1
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
99,154,41,11,170,13,75,144,212,17,19,151,26,188,61
|
1268,2018,1274,75,1648,2077,2328,154,2258,1280,1030,1708,2221,2177,2224,1710,917,2419,2331,2623,953,1434,1184,991,1187,1608,920,563,13,1086,2702,1233,2574,755,1188,151,691,17,236,2646,665,1239,26,1502,1341,2527,2500,502,1294,1725,2425,415,1243,1344,894,331,1456,1731,2786,1835,2579,856,311,11,1009,530,393,2109,2484,170,19,1842,2117,2799,144,2772,61,2440,2375,2165,99,188,713,1223,656,866,636,41,1176,212,908
|
-0.031687014709587694,-0.4276312314054814,-0.031687014709587694,2.358827559058653,-0.2256084890274861,-0.457189555658307,-0.6383986218099443,1.5458110822803104,-0.5772466087129535,-0.031687014709587694,0.10219020816314191,-0.25395864506177507,-0.5469546575117772,-0.5168492233508618,-0.5469546575117772,-0.25395864506177507,0.1807547309326192,-0.7315799679422195,-0.6383986218099443,-1.0555468822980754,0.15470992714805706,-0.11384263369455079,0.022313356391112545,0.1285222344905635,0.022313356391112545,-0.19742355434165754,0.1807547309326192,0.5069552146823165,3.948903861103401,0.07571238201592677,-1.4020919554916431,-0.004610885946918551,-0.9561113158015919,0.3088845403658546,0.022313356391112545,1.565142433258028,0.35918453124975014,3.539634851198567,1.1830609814557924,-1.1229595856058519,0.38413580421459165,-0.004610885946918551,3.3640668856918023,-0.1415423442786107,-0.05891660926003703,-0.858631173481535,-0.8265602308855787,0.5791408457585902,-0.031687014709587694,-0.25395864506177507,-0.7315799679422195,0.7202683829276397,-0.004610885946918551,-0.05891660926003703,0.2066580696947229,0.9020494934900769,-0.11384263369455079,-0.25395864506177507,-2.702906874607414,-0.311161791776721,-0.9561113158015919,0.23242134673518783,0.9684284143189831,4.176415817828502,0.1285222344905635,0.5552017244663052,0.7663817253435458,-0.457189555658307,-0.7946963348979321,1.4676530771754677,3.539634851198567,-0.311161791776721,-0.457189555658307,-3.9471181580065227,1.6416545156496378,-2.1342282062168807,2.517478261676434,-0.7315799679422195,-0.6692630532977037,-0.48692821008242365,2.0753063950252693,1.3881308939912163,0.35918453124975014,0.022313356391112545,0.40895629462372546,0.23242134673518783,0.43364725460652315,2.8619031325793367,0.04908726812999223,1.3072002040011301,0.2066580696947229
| 2,812
|
Intracellular signaling by second messengers
| 26
| 74
| 2.534468
| 0.011262
|
O00231,P49721,P10644,P62993,Q15022,P25788,P28072,P49720,P30154,P61289,P28074,Q99436,O43865,Q8IXK0,Q9HCE1,Q06124,O75832,Q92769,P31751,P20618,P30153,P28070,O95983,Q9UL46,P60900,P42345
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
514,18,520,523,549,292,45,314,190,568,70,199,328,458,609,95,347,492,227,102,486,110,358,512,120,501
|
514,2072,1481,2383,1271,328,2384,347,1762,358,1707,520,2023,1332,1917,2644,1186,102,1970,1558,292,1288,1087,110,45,70,1769,486,190,227,1775,501,1131,845,314,18,2267,923,120,568,926,1666,1139,523,1400,1296,2720,95,1449,2272,1830,1198,2099,1890,1147,1148,1149,549,2667,1792,458,1313,492,738,199,1531,633,2672,609,1263,1589,512,1538,1643
|
0.5552017244663052,-0.457189555658307,-0.1415423442786107,-0.7003227426014513,-0.031687014709587694,0.9020494934900769,-0.7003227426014513,0.8347092158473343,-0.28247580804102473,0.8120443818425275,-0.25395864506177507,0.5552017244663052,-0.4276312314054814,-0.05891660926003703,-0.36904762138247893,-1.1229595856058519,0.022313356391112545,2.005881846159429,-0.39825124132052653,-0.16940208304943802,1.012159267293361,-0.031687014709587694,0.07571238201592677,1.899680038524244,2.759934875525814,2.4229764762472206,-0.28247580804102473,0.6029587324284209,1.3680320463287143,1.2248145512604927,-0.28247580804102473,0.5791408457585902,0.04908726812999223,0.23242134673518783,0.946407369350807,3.539634851198567,-0.5772466087129535,0.1807547309326192,1.8274547643749006,0.5069552146823165,0.1807547309326192,-0.2256084890274861,0.04908726812999223,0.5552017244663052,-0.08630127296868081,-0.031687014709587694,-1.5109011257882559,2.1096173622141015,-0.11384263369455079,-0.5772466087129535,-0.311161791776721,0.022313356391112545,-0.457189555658307,-0.34001843888349026,0.04908726812999223,0.04908726812999223,0.04908726812999223,0.5311402316133299,-1.1912964858988957,-0.28247580804102473,0.6502352734037639,-0.031687014709587694,0.6029587324284209,0.3341012059117994,1.3478444644435112,-0.1415423442786107,0.43364725460652315,-1.1912964858988957,0.45820991892635715,-0.004610885946918551,-0.16940208304943802,0.5791408457585902,-0.1415423442786107,-0.19742355434165754
| 2,812
|
Azurophil granule lumen
| 10
| 39
| 2.521877
| 0.011673
|
P16278,P10619,O00584,P06280,Q9BTY2,Q92820,P08236,P07437,Q9H7Z7,P17900
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
161,67,159,168,143,76,148,246,125,251
|
159,1274,2021,384,168,2224,246,2080,148,67,1126,811,161,251,1769,1610,1190,1238,1566,620,1339,2142,641,414,261,1620,1000,1887,1889,1105,76,1360,1531,2751,143,125,1587,1800,2688
|
1.4873187834566612,-0.031687014709587694,-0.4276312314054814,0.7663817253435458,1.4676530771754677,-0.5469546575117772,1.1620412739234138,-0.457189555658307,1.5843918203314797,2.4704816361758035,0.04908726812999223,0.2580459451927195,1.4873187834566612,1.1409252165655943,-0.28247580804102473,-0.19742355434165754,0.022313356391112545,-0.004610885946918551,-0.16940208304943802,0.43364725460652315,-0.05891660926003703,-0.48692821008242365,0.40895629462372546,0.7202683829276397,1.119711996032066,-0.19742355434165754,0.1285222344905635,-0.34001843888349026,-0.34001843888349026,0.07571238201592677,2.358827559058653,-0.05891660926003703,-0.1415423442786107,-1.7742810257372263,1.6416545156496378,1.809215592081938,-0.16940208304943802,-0.28247580804102473,-1.260581097169132
| 2,812
|
Skin nodule
| 7
| 22
| 2.519229
| 0.011761
|
O75874,P01889,P06280,P35637,Q15437,P48735,Q06124
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
135,167,168,141,114,57,95
|
870,135,167,168,725,991,196,2755,1291,141,57,585,1040,757,1506,95,1346,114,432,2585,438,1423
|
0.2066580696947229,1.6605823293503985,1.4676530771754677,1.4676530771754677,0.3341012059117994,0.1285222344905635,1.3478444644435112,-1.9311426944841017,-0.031687014709587694,1.6416545156496378,2.533032514844444,0.4826455052953858,0.10219020816314191,0.3088845403658546,-0.1415423442786107,2.1096173622141015,-0.05891660926003703,1.8637126046605421,0.6970401416277441,-0.9561113158015919,0.6970401416277441,-0.08630127296868081
| 2,812
|
Proteasome core complex beta subunit complex
| 6
| 7
| 2.519097
| 0.011766
|
P28074,P20618,Q99436,P28072,P28070,P49721
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
70,102,199,45,110,18
|
102,110,45,70,314,18,199
|
2.005881846159429,1.899680038524244,2.759934875525814,2.4229764762472206,0.946407369350807,3.539634851198567,1.3478444644435112
| 2,812
|
Proteasome B-type subunit [IPR023333]
| 6
| 7
| 2.519097
| 0.011766
|
P28074,P20618,Q99436,P28072,P28070,P49721
|
Sequence
|
InterPro Family
|
interpro_family
|
70,102,199,45,110,18
|
102,110,45,70,314,18,199
|
2.005881846159429,1.899680038524244,2.759934875525814,2.4229764762472206,0.946407369350807,3.539634851198567,1.3478444644435112
| 2,812
|
Signaling by insulin receptor
| 8
| 15
| 2.511792
| 0.012012
|
P31751,Q9Y487,Q93050,Q15904,P36543,P62993,P61421,Q06124
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
227,41,170,239,151,523,502,95
|
920,563,1769,227,151,691,502,523,95,239,170,1686,1223,41,1176
|
0.1807547309326192,0.5069552146823165,-0.28247580804102473,1.2248145512604927,1.565142433258028,0.35918453124975014,0.5791408457585902,0.5552017244663052,2.1096173622141015,1.1830609814557924,1.4676530771754677,-0.2256084890274861,0.022313356391112545,2.8619031325793367,0.04908726812999223
| 2,812
|
Peptide catabolic process
| 7
| 10
| 2.51121
| 0.012032
|
Q99829,O14773,P55786,P42892,Q6P179,Q9UIQ6,P09960
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
396,100,386,86,279,25,287
|
100,287,1085,86,386,279,396,2067,438,25
|
2.0407291615321252,1.0338708607112133,0.07571238201592677,2.2608201286194824,0.7663817253435458,1.0769907617339176,0.7663817253435458,-0.4276312314054814,0.6970401416277441,3.376851885313292
| 2,812
|
Regulation of pattern recognition receptor signaling pathway
| 7
| 16
| 2.50511
| 0.012241
|
O75179,Q9NQC3,Q9NUD5,Q06481,Q9UKG1,Q9NPR9,O43657
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
195,266,203,111,409,54,370
|
1024,370,195,872,2300,1657,111,790,892,428,1462,1211,54,266,203,409
|
0.10219020816314191,0.789268883456853,1.3478444644435112,0.2066580696947229,-0.6077272079458682,-0.2256084890274861,1.899680038524244,0.2835332284224711,0.2066580696947229,0.6970401416277441,-0.11384263369455079,0.022313356391112545,2.5639762514184214,1.119711996032066,1.3275674269755584,0.7433818990772783
| 2,812
|
Peptidyl tyrosine modification
| 12
| 31
| 2.499455
| 0.012438
|
Q9H2J4,Q8WXW3,P45985,Q13432,Q92769,P14174,P30153,Q02750,Q96KB5,O95684,Q9H223,Q06124
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
130,325,322,389,492,260,486,362,477,155,356,95
|
155,1707,1553,260,1389,1185,882,486,1089,501,322,1724,362,95,1401,389,1675,325,492,1939,2694,477,1113,1363,356,130,1469,1263,1950,744,613
|
1.5263971248405028,-0.25395864506177507,-0.16940208304943802,1.119711996032066,-0.08630127296868081,0.022313356391112545,0.2066580696947229,0.6029587324284209,0.07571238201592677,0.5791408457585902,0.9242813695324721,-0.25395864506177507,0.8120443818425275,2.1096173622141015,-0.08630127296868081,0.7663817253435458,-0.2256084890274861,0.9242813695324721,0.6029587324284209,-0.36904762138247893,-1.3308378140240442,0.6266565061101952,0.07571238201592677,-0.05891660926003703,0.8347092158473343,1.7168950201979138,-0.11384263369455079,-0.004610885946918551,-0.36904762138247893,0.3341012059117994,0.45820991892635715
| 2,812
|
Corneal opacity
| 8
| 42
| 2.497241
| 0.012516
|
P16278,P10619,O43505,Q06136,O96028,P08236,P04062,O75844
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
161,67,47,113,147,148,87,56
|
2130,47,1760,658,1649,1229,56,1865,2258,147,1487,87,384,168,148,1555,67,161,539,881,2755,1774,521,692,425,1040,2092,1885,1506,113,526,1346,2428,1005,1203,1835,1210,2212,1372,1950,836,1753
|
-0.48692821008242365,2.7303554016709937,-0.28247580804102473,0.38413580421459165,-0.2256084890274861,-0.004610885946918551,2.533032514844444,-0.34001843888349026,-0.5772466087129535,1.6035598788121985,-0.1415423442786107,2.24427219514418,0.7663817253435458,1.4676530771754677,1.5843918203314797,-0.16940208304943802,2.4704816361758035,1.4873187834566612,0.5311402316133299,0.2066580696947229,-1.9311426944841017,-0.28247580804102473,0.5552017244663052,0.35918453124975014,0.6970401416277441,0.10219020816314191,-0.457189555658307,-0.34001843888349026,-0.1415423442786107,1.8637126046605421,0.5552017244663052,-0.05891660926003703,-0.7315799679422195,0.1285222344905635,0.022313356391112545,-0.311161791776721,0.022313356391112545,-0.5168492233508618,-0.05891660926003703,-0.36904762138247893,0.2580459451927195,-0.25395864506177507
| 2,812
|
Cytoprotection by hmox1
| 13
| 60
| 2.482981
| 0.013029
|
Q8TCT9,P25788,P28074,Q99436,P20618,P28072,P09601,P28070,P49721,Q86X55,P60900,P49720,P30519
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
324,292,70,199,102,45,79,110,18,215,120,314,30
|
514,2072,2449,1481,2383,1271,689,347,871,1280,79,2605,2331,1184,1331,1917,1186,102,1608,1970,1558,292,1288,1087,110,45,70,2607,30,755,1775,2789,1130,1131,845,314,18,2267,997,120,568,926,1666,1139,666,1296,1449,2272,2546,1987,2100,1148,1149,215,324,478,199,1531,512,1643
|
0.5552017244663052,-0.457189555658307,-0.7630370464216969,-0.1415423442786107,-0.7003227426014513,-0.031687014709587694,0.35918453124975014,0.8347092158473343,0.2066580696947229,-0.031687014709587694,2.342643329037244,-1.0221799869805437,-0.6383986218099443,0.022313356391112545,-0.05891660926003703,-0.36904762138247893,0.022313356391112545,2.005881846159429,-0.19742355434165754,-0.39825124132052653,-0.16940208304943802,1.012159267293361,-0.031687014709587694,0.07571238201592677,1.899680038524244,2.759934875525814,2.4229764762472206,-1.0221799869805437,3.247236697579701,0.3088845403658546,-0.28247580804102473,-2.749330655939741,0.04908726812999223,0.04908726812999223,0.23242134673518783,0.946407369350807,3.539634851198567,-0.5772466087129535,0.1285222344905635,1.8274547643749006,0.5069552146823165,0.1807547309326192,-0.2256084890274861,0.04908726812999223,0.38413580421459165,-0.031687014709587694,-0.11384263369455079,-0.5772466087129535,-0.8909116443167836,-0.39825124132052653,-0.457189555658307,0.04908726812999223,0.04908726812999223,1.2867420568988635,0.9242813695324721,0.6266565061101952,1.3478444644435112,-0.1415423442786107,0.5791408457585902,-0.19742355434165754
| 2,812
|
Splenomegaly
| 21
| 77
| 2.478381
| 0.013198
|
P15260,P14174,Q15392,P04066,P21964,P08236,P16278,P61916,P01889,P10253,O15118,P54802,Q14108,Q6PGP7,P04062,Q14739,P07602,P28070,Q15437,Q15904,O14936
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
132,260,10,384,270,148,161,414,167,301,82,83,84,341,87,232,101,110,114,239,119
|
1702,1269,2073,119,82,805,1862,1325,987,1431,1550,2298,167,1487,87,384,2452,1707,1488,2222,101,148,301,2623,724,1490,1282,2689,260,132,811,161,2643,1918,920,270,2724,2180,110,993,1770,1393,1088,1292,585,664,1397,1567,1780,83,2235,414,2613,525,1346,2692,84,232,10,114,2399,239,341,1010,2245,1211,650,2408,706,1902,2004,2772,2442,1071,438,1020,1694
|
-0.25395864506177507,-0.031687014709587694,-0.457189555658307,1.8274547643749006,2.326399504773361,0.2580459451927195,-0.34001843888349026,-0.05891660926003703,0.1285222344905635,-0.11384263369455079,-0.16940208304943802,-0.6077272079458682,1.4676530771754677,-0.1415423442786107,2.24427219514418,0.7663817253435458,-0.7630370464216969,-0.25395864506177507,-0.1415423442786107,-0.5469546575117772,2.0233395056563532,1.5843918203314797,0.9903454141911546,-1.0555468822980754,0.3341012059117994,-0.1415423442786107,-0.031687014709587694,-1.29558638215688,1.119711996032066,1.679431285350743,0.2580459451927195,1.4873187834566612,-1.1229595856058519,-0.36904762138247893,0.1807547309326192,1.098400788944567,-1.54769869262779,-0.5168492233508618,1.899680038524244,0.1285222344905635,-0.28247580804102473,-0.08630127296868081,0.07571238201592677,-0.031687014709587694,0.4826455052953858,0.38413580421459165,-0.08630127296868081,-0.16940208304943802,-0.28247580804102473,2.310095682444116,-0.5469546575117772,0.7202683829276397,-1.0221799869805437,0.5552017244663052,-0.05891660926003703,-1.3308378140240442,2.277306408278314,1.2248145512604927,4.4515440828239035,1.8637126046605421,-0.7003227426014513,1.1830609814557924,0.8572643679612094,0.1285222344905635,-0.5469546575117772,0.022313356391112545,0.40895629462372546,-0.7003227426014513,0.35918453124975014,-0.34001843888349026,-0.39825124132052653,-2.1342282062168807,-0.7315799679422195,0.10219020816314191,0.6970401416277441,0.1285222344905635,-0.2256084890274861
| 2,812
|
Interferon gamma signaling
| 8
| 13
| 2.47409
| 0.013358
|
O15344,P10321,P15260,P01889,P19474,Q14258,Q06124,P04439
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
440,312,132,167,116,547,95,160
|
440,167,160,312,132,1389,116,564,1443,95,1096,2099,547
|
0.6736961261378334,1.4676530771754677,1.4873187834566612,0.946407369350807,1.679431285350743,-0.08630127296868081,1.8456202538155837,0.5069552146823165,-0.11384263369455079,2.1096173622141015,0.07571238201592677,-0.457189555658307,0.5311402316133299
| 2,812
|
K Homology domain [IPR004087]
| 10
| 24
| 2.471119
| 0.013469
|
O75179,Q06787,Q96PU8,P51116,Q92945,P61978,O75525,Q96I24,P51114,Q07666
|
Sequence
|
InterPro Domain
|
interpro_domain
|
195,350,463,137,178,207,371,375,58,316
|
688,195,371,58,137,207,1670,350,316,1144,763,1202,2548,2344,2054,1527,178,705,375,463,1170,1264,1074,556
|
0.35918453124975014,1.3478444644435112,0.789268883456853,2.533032514844444,1.6605823293503985,1.3072002040011301,-0.2256084890274861,0.8347092158473343,0.946407369350807,0.04908726812999223,0.3088845403658546,0.022313356391112545,-0.8909116443167836,-0.6383986218099443,-0.4276312314054814,-0.1415423442786107,1.447902119529762,0.35918453124975014,0.789268883456853,0.6502352734037639,0.04908726812999223,-0.004610885946918551,0.10219020816314191,0.5311402316133299
| 2,812
|
Ns1 mediated effects on host pathways
| 9
| 34
| 2.461335
| 0.013842
|
P55735,O00505,Q9BW27,Q9BTX1,O00629,P52294,Q8NFH4,P57740,Q12769
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
129,31,466,494,42,43,240,284,505
|
31,42,910,950,1388,1185,1875,1235,1663,960,923,43,2233,129,284,2395,505,1051,1204,1578,1519,971,1898,240,1793,1311,1413,2463,533,494,2119,466,1744,1373
|
3.16753088514317,2.803929621091696,0.1807547309326192,0.15470992714805706,-0.08630127296868081,0.022313356391112545,-0.34001843888349026,-0.004610885946918551,-0.2256084890274861,0.15470992714805706,0.1807547309326192,2.789314221988835,-0.5469546575117772,1.7168950201979138,1.0554810704738096,-0.7003227426014513,0.5791408457585902,0.10219020816314191,0.022313356391112545,-0.16940208304943802,-0.1415423442786107,0.15470992714805706,-0.34001843888349026,1.1830609814557924,-0.28247580804102473,-0.031687014709587694,-0.08630127296868081,-0.7630370464216969,0.5552017244663052,0.6029587324284209,-0.457189555658307,0.6502352734037639,-0.25395864506177507,-0.05891660926003703
| 2,812
|
Cytokine production
| 26
| 89
| 2.461116
| 0.013851
|
P30536,P15260,P14174,Q9UKG1,P04083,P04439,Q01650,P01889,Q92990,O43823,P31483,O60684,Q53EL6,Q8WXW3,Q8IV08,Q9NUD5,P09601,P04062,Q9BYW2,Q9NUQ9,Q06124,Q92769,Q06481,P19474,Q99943,Q9Y624
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
0,132,260,409,269,160,415,167,432,166,424,185,447,325,73,203,79,87,344,89,95,492,111,116,377,249
|
688,1024,2130,166,185,2134,872,1548,2298,167,87,269,2079,160,483,808,1387,2300,1765,79,1555,1657,2658,260,132,1814,2589,1918,116,1185,1187,1714,2085,0,424,2474,2789,1089,1443,1614,2362,1662,1504,1400,667,1044,415,1300,95,111,790,1095,2044,1510,2692,2239,550,447,73,2708,1462,325,1410,492,1211,1939,432,2532,1902,633,2061,377,2160,860,344,2711,634,1420,203,89,1641,742,1264,2698,1749,409,2327,249,556
|
0.35918453124975014,0.10219020816314191,-0.48692821008242365,1.4676530771754677,1.3881308939912163,-0.48692821008242365,0.2066580696947229,-0.16940208304943802,-0.6077272079458682,1.4676530771754677,2.24427219514418,1.098400788944567,-0.457189555658307,1.4873187834566612,0.6029587324284209,0.2580459451927195,-0.08630127296868081,-0.6077272079458682,-0.28247580804102473,2.342643329037244,-0.16940208304943802,-0.2256084890274861,-1.1570110616486227,1.119711996032066,1.679431285350743,-0.311161791776721,-0.9890357013357498,-0.36904762138247893,1.8456202538155837,0.022313356391112545,0.022313356391112545,-0.25395864506177507,-0.457189555658307,5.472379812321296,0.6970401416277441,-0.7946963348979321,-2.749330655939741,0.07571238201592677,-0.11384263369455079,-0.19742355434165754,-0.6692630532977037,-0.2256084890274861,-0.1415423442786107,-0.08630127296868081,0.38413580421459165,0.10219020816314191,0.7202683829276397,-0.031687014709587694,2.1096173622141015,1.899680038524244,0.2835332284224711,0.07571238201592677,-0.4276312314054814,-0.1415423442786107,-1.3308378140240442,-0.5469546575117772,0.5311402316133299,0.6736961261378334,2.3910188320042183,-1.4381012368155113,-0.11384263369455079,0.9242813695324721,-0.08630127296868081,0.6029587324284209,0.022313356391112545,-0.36904762138247893,0.6970401416277441,-0.858631173481535,-0.34001843888349026,0.43364725460652315,-0.4276312314054814,0.789268883456853,-0.48692821008242365,0.23242134673518783,0.8572643679612094,-1.4381012368155113,0.43364725460652315,-0.08630127296868081,1.3275674269755584,2.1942542072619107,-0.19742355434165754,0.3341012059117994,-0.004610885946918551,-1.3663385868789217,-0.25395864506177507,0.7433818990772783,-0.6077272079458682,1.1620412739234138,0.5311402316133299
| 2,812
|
Cellular response to biotic stimulus
| 11
| 32
| 2.460797
| 0.013863
|
P30536,Q16539,O76024,Q8WTV0,Q8IXJ6,P14174,P08670,O43823,O75844,Q9NUQ9,Q53EL6
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
0,550,561,37,508,260,385,166,56,89,447
|
166,56,561,1707,385,2300,725,260,2589,2085,1769,0,1290,1403,550,447,1677,855,1352,1519,1520,508,1103,37,2157,650,1841,1068,89,1947,866,614
|
1.4676530771754677,2.533032514844444,0.5069552146823165,-0.25395864506177507,0.7663817253435458,-0.6077272079458682,0.3341012059117994,1.119711996032066,-0.9890357013357498,-0.457189555658307,-0.28247580804102473,5.472379812321296,-0.031687014709587694,-0.08630127296868081,0.5311402316133299,0.6736961261378334,-0.2256084890274861,0.23242134673518783,-0.05891660926003703,-0.1415423442786107,-0.1415423442786107,0.5791408457585902,0.07571238201592677,3.0312962380643427,-0.48692821008242365,0.40895629462372546,-0.311161791776721,0.10219020816314191,2.1942542072619107,-0.36904762138247893,0.23242134673518783,0.45820991892635715
| 2,812
|
Molecular transducer activity
| 15
| 31
| 2.455753
| 0.014059
|
P30536,Q8WTV0,P15260,P11717,Q5KU26,Q07954,Q4VCS5,Q99523,O15118,O43813,O15173,Q14108,Q15629,Q6RW13,P10586
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
0,37,132,321,490,374,332,337,82,518,51,84,310,448,562
|
82,51,518,2176,1553,562,321,132,1815,0,2789,585,2396,374,2044,2148,84,310,1456,332,490,1732,448,37,2484,337,1112,977,1263,2289,982
|
2.326399504773361,2.6252145052389237,0.5552017244663052,-0.5168492233508618,-0.16940208304943802,0.5069552146823165,0.9242813695324721,1.679431285350743,-0.311161791776721,5.472379812321296,-2.749330655939741,0.4826455052953858,-0.7003227426014513,0.789268883456853,-0.4276312314054814,-0.48692821008242365,2.277306408278314,0.9684284143189831,-0.11384263369455079,0.9020494934900769,0.6029587324284209,-0.25395864506177507,0.6736961261378334,3.0312962380643427,-0.7946963348979321,0.8797108080344074,0.07571238201592677,0.15470992714805706,-0.004610885946918551,-0.5772466087129535,0.15470992714805706
| 2,812
|
K Homology domain, type 1 [IPR004088]
| 14
| 25
| 2.454455
| 0.01411
|
O75179,Q06787,Q8N9N2,Q96PU8,P51116,O00425,Q92945,P61978,O75525,Q96I24,P51114,Q9Y6M1,Q07666,Q96AE4
|
Sequence
|
InterPro Domain
|
interpro_domain
|
195,350,649,463,137,688,178,207,371,375,58,556,316,705
|
688,195,371,58,137,207,1670,350,316,1003,763,1202,2548,2344,649,2054,1527,178,705,375,463,1167,1264,1074,556
|
0.35918453124975014,1.3478444644435112,0.789268883456853,2.533032514844444,1.6605823293503985,1.3072002040011301,-0.2256084890274861,0.8347092158473343,0.946407369350807,0.1285222344905635,0.3088845403658546,0.022313356391112545,-0.8909116443167836,-0.6383986218099443,0.40895629462372546,-0.4276312314054814,-0.1415423442786107,1.447902119529762,0.35918453124975014,0.789268883456853,0.6502352734037639,0.04908726812999223,-0.004610885946918551,0.10219020816314191,0.5311402316133299
| 2,812
|
G2 m checkpoints
| 13
| 75
| 2.4543
| 0.014116
|
P25788,P28074,Q99436,P20618,P28072,Q9NXR7,Q9Y619,P28070,P49721,O96028,Q9UQ84,P60900,P49720
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
292,70,199,102,45,210,212,110,18,147,118,120,314
|
514,2072,1481,2383,1271,2075,1811,347,1382,876,147,1707,1764,1330,954,2179,1917,102,955,1873,1970,1558,292,1288,1561,1816,1087,110,45,70,817,1393,1661,1772,2389,1774,1775,2186,2498,1131,845,314,18,996,822,2267,120,568,1091,926,1666,1138,1139,2661,1343,1093,1449,570,2272,760,1246,1832,1148,1149,1526,1899,199,1531,210,534,512,1643,118,657,212
|
0.5552017244663052,-0.457189555658307,-0.1415423442786107,-0.7003227426014513,-0.031687014709587694,-0.457189555658307,-0.311161791776721,0.8347092158473343,-0.08630127296868081,0.2066580696947229,1.6035598788121985,-0.25395864506177507,-0.28247580804102473,-0.05891660926003703,0.15470992714805706,-0.5168492233508618,-0.36904762138247893,2.005881846159429,0.15470992714805706,-0.34001843888349026,-0.39825124132052653,-0.16940208304943802,1.012159267293361,-0.031687014709587694,-0.16940208304943802,-0.311161791776721,0.07571238201592677,1.899680038524244,2.759934875525814,2.4229764762472206,0.2580459451927195,-0.08630127296868081,-0.2256084890274861,-0.28247580804102473,-0.7003227426014513,-0.28247580804102473,-0.28247580804102473,-0.5168492233508618,-0.8265602308855787,0.04908726812999223,0.23242134673518783,0.946407369350807,3.539634851198567,0.1285222344905635,0.2580459451927195,-0.5772466087129535,1.8274547643749006,0.5069552146823165,0.07571238201592677,0.1807547309326192,-0.2256084890274861,0.04908726812999223,0.04908726812999223,-1.1570110616486227,-0.05891660926003703,0.07571238201592677,-0.11384263369455079,0.5069552146823165,-0.5772466087129535,0.3088845403658546,-0.004610885946918551,-0.311161791776721,0.04908726812999223,0.04908726812999223,-0.1415423442786107,-0.34001843888349026,1.3478444644435112,-0.1415423442786107,1.3072002040011301,0.5552017244663052,0.5791408457585902,-0.19742355434165754,1.8456202538155837,0.40895629462372546,1.3072002040011301
| 2,812
|
Circulatory system process
| 15
| 65
| 2.454233
| 0.014119
|
Q01650,Q9HB40,Q07954,P78417,Q9Y5X3,Q9NZ08,P42785,P09601,P10253,P08183,P42892,Q6P179,O75844,Q9UIQ6,P53985
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
415,36,374,74,439,438,15,79,301,205,86,279,56,25,26
|
594,1269,2018,950,56,1182,2295,2021,660,2175,1866,1030,1708,205,723,79,301,2623,1491,2454,2538,991,1332,1187,1659,885,816,1233,755,1443,501,15,86,756,2560,1721,26,1502,1341,1240,1138,74,415,1300,544,374,2237,527,1347,1201,1456,279,2579,1734,448,2551,1528,2771,2440,1166,36,438,1694,25,439
|
0.45820991892635715,-0.031687014709587694,-0.4276312314054814,0.15470992714805706,2.533032514844444,0.022313356391112545,-0.6077272079458682,-0.4276312314054814,0.38413580421459165,-0.5168492233508618,-0.34001843888349026,0.10219020816314191,-0.25395864506177507,1.3072002040011301,0.3341012059117994,2.342643329037244,0.9903454141911546,-1.0555468822980754,-0.1415423442786107,-0.7630370464216969,-0.8909116443167836,0.1285222344905635,-0.05891660926003703,0.022313356391112545,-0.2256084890274861,0.2066580696947229,0.2580459451927195,-0.004610885946918551,0.3088845403658546,-0.11384263369455079,0.5791408457585902,3.937751240269287,2.2608201286194824,0.3088845403658546,-0.9234041685354025,-0.25395864506177507,3.3640668856918023,-0.1415423442786107,-0.05891660926003703,-0.004610885946918551,0.04908726812999223,2.3749525947181227,0.7202683829276397,-0.031687014709587694,0.5311402316133299,0.789268883456853,-0.5469546575117772,0.5552017244663052,-0.05891660926003703,0.022313356391112545,-0.11384263369455079,1.0769907617339176,-0.9561113158015919,-0.25395864506177507,0.6736961261378334,-0.8909116443167836,-0.1415423442786107,-2.1342282062168807,-0.7315799679422195,0.04908726812999223,3.0588916001916124,0.6970401416277441,-0.2256084890274861,3.376851885313292,0.6970401416277441
| 2,812
|
Protein targeting to mitochondrion
| 7
| 44
| 2.45226
| 0.014196
|
P30536,Q9Y512,Q9NS69,Q99595,O60830,O14737,Q5JRX3
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
0,165,5,8,9,175,157
|
1267,175,516,720,9,2219,1548,1654,1706,538,1385,808,2658,1186,0,2029,1133,2089,386,2545,525,668,764,1785,932,850,157,1307,235,531,633,8,858,2631,2761,1417,5,1073,2704,1948,714,1854,536,165
|
-0.031687014709587694,1.447902119529762,0.5552017244663052,0.3341012059117994,4.51024026447363,-0.5469546575117772,-0.16940208304943802,-0.2256084890274861,-0.25395864506177507,0.5311402316133299,-0.08630127296868081,0.2580459451927195,-1.1570110616486227,0.022313356391112545,5.472379812321296,-0.4276312314054814,0.04908726812999223,-0.457189555658307,0.7663817253435458,-0.8909116443167836,0.5552017244663052,0.38413580421459165,0.3088845403658546,-0.28247580804102473,0.1807547309326192,0.23242134673518783,1.5263971248405028,-0.031687014709587694,1.2039851426447223,0.5552017244663052,0.43364725460652315,4.519940897786278,0.23242134673518783,-1.0555468822980754,-1.9711219201568242,-0.08630127296868081,4.736858349607043,0.10219020816314191,-1.4020919554916431,-0.36904762138247893,0.35918453124975014,-0.311161791776721,0.5552017244663052,1.4873187834566612
| 2,812
|
Rigidity
| 7
| 50
| 2.450476
| 0.014267
|
P16278,Q96CU9,P07602,Q9Y287,Q15392,P04062,O14936
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
161,4,101,174,10,87,119
|
2017,119,1274,2132,1431,877,87,101,953,161,1916,1185,2574,2229,1235,691,228,663,960,2560,1040,925,1091,1447,961,695,350,1827,1050,10,1404,1998,933,934,4,1684,1633,740,2061,2348,2320,1419,1020,1538,2675,614,174,536,1856,1953
|
-0.4276312314054814,1.8274547643749006,-0.031687014709587694,-0.48692821008242365,-0.11384263369455079,0.2066580696947229,2.24427219514418,2.0233395056563532,0.15470992714805706,1.4873187834566612,-0.36904762138247893,0.022313356391112545,-0.9561113158015919,-0.5469546575117772,-0.004610885946918551,0.35918453124975014,1.2248145512604927,0.38413580421459165,0.15470992714805706,-0.9234041685354025,0.10219020816314191,0.1807547309326192,0.07571238201592677,-0.11384263369455079,0.15470992714805706,0.35918453124975014,0.8347092158473343,-0.311161791776721,0.10219020816314191,4.4515440828239035,-0.08630127296868081,-0.39825124132052653,0.1807547309326192,0.1807547309326192,4.773418117753822,-0.2256084890274861,-0.19742355434165754,0.3341012059117994,-0.4276312314054814,-0.6383986218099443,-0.6077272079458682,-0.08630127296868081,0.1285222344905635,-0.1415423442786107,-1.1912964858988957,0.45820991892635715,1.4676530771754677,0.5552017244663052,-0.311161791776721,-0.36904762138247893
| 2,812
|
K Homology domain, type 1 superfamily [IPR036612]
| 14
| 27
| 2.447385
| 0.01439
|
O75179,Q06787,Q8N9N2,Q96PU8,P51116,O00425,Q92945,P61978,O75525,Q96I24,P51114,Q9Y6M1,Q07666,Q96AE4
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
195,350,649,463,137,688,178,207,371,375,58,556,316,705
|
688,195,371,58,137,207,1670,350,316,1144,1003,763,1202,2548,2344,649,2054,1527,178,705,375,463,1167,1170,1264,1074,556
|
0.35918453124975014,1.3478444644435112,0.789268883456853,2.533032514844444,1.6605823293503985,1.3072002040011301,-0.2256084890274861,0.8347092158473343,0.946407369350807,0.04908726812999223,0.1285222344905635,0.3088845403658546,0.022313356391112545,-0.8909116443167836,-0.6383986218099443,0.40895629462372546,-0.4276312314054814,-0.1415423442786107,1.447902119529762,0.35918453124975014,0.789268883456853,0.6502352734037639,0.04908726812999223,0.04908726812999223,-0.004610885946918551,0.10219020816314191,0.5311402316133299
| 2,812
|
Metalloprotease
| 12
| 26
| 2.431616
| 0.015032
|
Q9BYT8,P52888,P55786,Q9NZ08,O75976,P42892,Q6P179,Q9NQH7,Q9UIQ6,O75844,Q5JRX3,P09960
|
Functions
|
Protein Atlas Molecular function
|
protein_atlas_molecular_function
|
397,567,386,438,268,86,279,580,25,56,157,287
|
1481,2356,2219,56,268,287,2689,1085,86,567,386,157,279,826,605,1316,1796,858,397,1639,580,2067,944,438,25,1953
|
-0.1415423442786107,-0.6692630532977037,-0.5469546575117772,2.533032514844444,1.098400788944567,1.0338708607112133,-1.29558638215688,0.07571238201592677,2.2608201286194824,0.5069552146823165,0.7663817253435458,1.5263971248405028,1.0769907617339176,0.2580459451927195,0.45820991892635715,-0.031687014709587694,-0.28247580804102473,0.23242134673518783,0.7663817253435458,-0.19742355434165754,0.5069552146823165,-0.4276312314054814,0.1807547309326192,0.6970401416277441,3.376851885313292,-0.36904762138247893
| 2,812
|
Mitochondrial protein import
| 6
| 31
| 2.427751
| 0.015193
|
Q9Y512,Q9NS69,Q99595,O60830,P21796,Q5JRX3
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
165,5,8,9,13,157
|
516,720,9,2358,2133,2219,2077,1548,1385,2177,2419,2658,953,1434,13,2702,2087,525,330,764,932,157,235,8,2602,1417,5,467,656,2127,165
|
0.5552017244663052,0.3341012059117994,4.51024026447363,-0.6692630532977037,-0.48692821008242365,-0.5469546575117772,-0.457189555658307,-0.16940208304943802,-0.08630127296868081,-0.5168492233508618,-0.7315799679422195,-1.1570110616486227,0.15470992714805706,-0.11384263369455079,3.948903861103401,-1.4020919554916431,-0.457189555658307,0.5552017244663052,0.9020494934900769,0.3088845403658546,0.1807547309326192,1.5263971248405028,1.2039851426447223,4.519940897786278,-0.9890357013357498,-0.08630127296868081,4.736858349607043,0.6502352734037639,0.40895629462372546,-0.457189555658307,1.4873187834566612
| 2,812
|
Interleukin 1 family signaling
| 13
| 45
| 2.419978
| 0.015521
|
O75832,P25788,P28074,Q99436,P45985,P20618,P28072,P28070,P49721,Q15750,P60900,P49720,Q06124
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
347,292,70,199,322,102,45,110,18,339,120,314,95
|
514,2072,1481,2383,1271,347,2300,1917,102,1970,1558,292,1288,1087,110,45,70,1775,2789,1131,322,845,314,18,2267,120,568,926,1666,1139,666,362,95,1449,2272,473,1987,1148,1149,339,199,1531,2698,512,1643
|
0.5552017244663052,-0.457189555658307,-0.1415423442786107,-0.7003227426014513,-0.031687014709587694,0.8347092158473343,-0.6077272079458682,-0.36904762138247893,2.005881846159429,-0.39825124132052653,-0.16940208304943802,1.012159267293361,-0.031687014709587694,0.07571238201592677,1.899680038524244,2.759934875525814,2.4229764762472206,-0.28247580804102473,-2.749330655939741,0.04908726812999223,0.9242813695324721,0.23242134673518783,0.946407369350807,3.539634851198567,-0.5772466087129535,1.8274547643749006,0.5069552146823165,0.1807547309326192,-0.2256084890274861,0.04908726812999223,0.38413580421459165,0.8120443818425275,2.1096173622141015,-0.11384263369455079,-0.5772466087129535,0.6266565061101952,-0.39825124132052653,0.04908726812999223,0.04908726812999223,0.8572643679612094,1.3478444644435112,-0.1415423442786107,-1.3663385868789217,0.5791408457585902,-0.19742355434165754
| 2,812
|
Bulbar signs
| 6
| 11
| 2.416753
| 0.01566
|
Q92734,P07602,P03886,P35637,P04062,P43243
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
532,101,451,141,87,522
|
1274,451,87,1230,101,141,522,532,1112,1020,614
|
-0.031687014709587694,0.6502352734037639,2.24427219514418,-0.004610885946918551,2.0233395056563532,1.6416545156496378,0.5552017244663052,0.5552017244663052,0.07571238201592677,0.1285222344905635,0.45820991892635715
| 2,812
|
Immunity
| 26
| 75
| 2.40369
| 0.016231
|
Q9NRW3,Q96FW1,P14174,P04083,O00743,P43243,Q6P179,P04439,O00584,P01889,Q9NZ08,P46379,O43823,P10321,Q8WXW3,O75179,Q9NUD5,Q8IV08,Q9BYW2,Q13501,P17931,O94992,P17812,Q9UQ84,Q8IXJ6,Q96PK6
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
398,133,260,269,515,522,279,160,159,167,438,46,166,312,325,195,203,73,344,473,469,482,359,118,508,256
|
1024,159,515,2130,1599,166,195,482,1552,167,269,2079,160,1709,2300,312,2571,2138,260,359,469,1918,1185,1495,1970,2085,1089,522,46,2091,925,787,667,790,1095,1096,1510,2546,1986,473,2547,547,1674,1202,279,1630,899,73,508,2208,1257,325,1410,772,1939,133,1902,256,2116,2160,860,344,2711,1420,398,203,1641,1849,438,2698,2126,946,118,1856,1700
|
0.10219020816314191,1.4873187834566612,0.5552017244663052,-0.48692821008242365,-0.19742355434165754,1.4676530771754677,1.3478444644435112,0.6029587324284209,-0.16940208304943802,1.4676530771754677,1.098400788944567,-0.457189555658307,1.4873187834566612,-0.25395864506177507,-0.6077272079458682,0.946407369350807,-0.9561113158015919,-0.48692821008242365,1.119711996032066,0.8120443818425275,0.6266565061101952,-0.36904762138247893,0.022313356391112545,-0.1415423442786107,-0.39825124132052653,-0.457189555658307,0.07571238201592677,0.5552017244663052,2.759934875525814,-0.457189555658307,0.1807547309326192,0.2835332284224711,0.38413580421459165,0.2835332284224711,0.07571238201592677,0.07571238201592677,-0.1415423442786107,-0.8909116443167836,-0.39825124132052653,0.6266565061101952,-0.8909116443167836,0.5311402316133299,-0.2256084890274861,0.022313356391112545,1.0769907617339176,-0.19742355434165754,0.2066580696947229,2.3910188320042183,0.5791408457585902,-0.5168492233508618,-0.004610885946918551,0.9242813695324721,-0.08630127296868081,0.3088845403658546,-0.36904762138247893,1.679431285350743,-0.34001843888349026,1.1409252165655943,-0.457189555658307,-0.48692821008242365,0.23242134673518783,0.8572643679612094,-1.4381012368155113,-0.08630127296868081,0.7663817253435458,1.3275674269755584,-0.19742355434165754,-0.311161791776721,0.6970401416277441,-1.3663385868789217,-0.457189555658307,0.1807547309326192,1.8456202538155837,-0.311161791776721,-0.2256084890274861
| 2,812
|
Liposaccharide metabolic process
| 6
| 15
| 2.400846
| 0.016357
|
P16278,P06280,P06865,P04062,Q8NBX0,P17900
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
161,168,150,87,122,251
|
617,805,87,384,168,150,2080,161,251,668,122,1011,1315,904,905
|
0.43364725460652315,0.2580459451927195,2.24427219514418,0.7663817253435458,1.4676530771754677,1.565142433258028,-0.457189555658307,1.4873187834566612,1.1409252165655943,0.38413580421459165,1.8274547643749006,0.1285222344905635,-0.031687014709587694,0.2066580696947229,0.2066580696947229
| 2,812
|
Positive regulation of cellular amide metabolic process
| 17
| 58
| 2.386205
| 0.017023
|
Q14103,P67809,O60506,Q9H074,Q06787,P15260,Q9Y2R0,P16989,P51116,P08670,Q71RC2,Q14011,Q567V2,P51114,P98179,Q07666,Q9BRP8
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
351,229,194,264,350,132,126,136,137,385,336,93,23,58,247,316,419
|
1024,2355,582,194,1650,1276,2222,385,412,1964,1436,132,136,1442,501,2592,2458,58,137,1503,2393,1823,1668,1446,229,2270,787,247,694,961,350,790,316,1095,1301,1887,2193,93,351,1574,23,602,336,1100,857,736,972,589,2733,419,1940,2439,264,1468,2711,1264,126,1700
|
0.10219020816314191,-0.6692630532977037,0.4826455052953858,1.3478444644435112,-0.2256084890274861,-0.031687014709587694,-0.5469546575117772,0.7663817253435458,0.7202683829276397,-0.39825124132052653,-0.11384263369455079,1.679431285350743,1.6605823293503985,-0.11384263369455079,0.5791408457585902,-0.9890357013357498,-0.7630370464216969,2.533032514844444,1.6605823293503985,-0.1415423442786107,-0.7003227426014513,-0.311161791776721,-0.2256084890274861,-0.11384263369455079,1.2248145512604927,-0.5772466087129535,0.2835332284224711,1.1620412739234138,0.35918453124975014,0.15470992714805706,0.8347092158473343,0.2835332284224711,0.946407369350807,0.07571238201592677,-0.031687014709587694,-0.34001843888349026,-0.5168492233508618,2.1266741669465663,0.8347092158473343,-0.16940208304943802,3.4149771349732063,0.45820991892635715,0.8797108080344074,0.07571238201592677,0.23242134673518783,0.3341012059117994,0.15470992714805706,0.4826455052953858,-1.6221069821762664,0.7202683829276397,-0.36904762138247893,-0.7315799679422195,1.119711996032066,-0.11384263369455079,-1.4381012368155113,-0.004610885946918551,1.809215592081938,-0.2256084890274861
| 2,812
|
Mitotic g2 g2 m phases
| 16
| 77
| 2.384639
| 0.017096
|
O94927,P25788,P20618,P28074,Q99436,P68371,P28072,P28070,P49721,O75935,P07437,Q9BVA1,P60900,P49720,O95684,P30154
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
348,292,102,70,199,261,45,110,18,52,246,248,120,314,155,190
|
514,2072,1481,2383,1861,1546,1271,347,52,348,1382,155,1707,1764,246,808,1387,1330,1332,1917,102,485,955,1970,1558,292,1288,1087,110,45,70,486,190,1775,2740,1131,845,692,314,18,2267,1664,120,2737,999,568,1091,1980,926,1666,1138,1139,1043,759,666,261,1449,2272,732,1987,2196,1050,1889,1148,1149,671,624,1999,2767,199,1531,741,682,248,512,2011,1643
|
0.5552017244663052,-0.457189555658307,-0.1415423442786107,-0.7003227426014513,-0.34001843888349026,-0.16940208304943802,-0.031687014709587694,0.8347092158473343,2.5793664440470323,0.8347092158473343,-0.08630127296868081,1.5263971248405028,-0.25395864506177507,-0.28247580804102473,1.1620412739234138,0.2580459451927195,-0.08630127296868081,-0.05891660926003703,-0.05891660926003703,-0.36904762138247893,2.005881846159429,0.6029587324284209,0.15470992714805706,-0.39825124132052653,-0.16940208304943802,1.012159267293361,-0.031687014709587694,0.07571238201592677,1.899680038524244,2.759934875525814,2.4229764762472206,0.6029587324284209,1.3680320463287143,-0.28247580804102473,-1.6976241927614946,0.04908726812999223,0.23242134673518783,0.35918453124975014,0.946407369350807,3.539634851198567,-0.5772466087129535,-0.2256084890274861,1.8274547643749006,-1.6597250820929819,0.1285222344905635,0.5069552146823165,0.07571238201592677,-0.39825124132052653,0.1807547309326192,-0.2256084890274861,0.04908726812999223,0.04908726812999223,0.10219020816314191,0.3088845403658546,0.38413580421459165,1.119711996032066,-0.11384263369455079,-0.5772466087129535,0.3341012059117994,-0.39825124132052653,-0.5168492233508618,0.10219020816314191,-0.34001843888349026,0.04908726812999223,0.04908726812999223,0.38413580421459165,0.43364725460652315,-0.39825124132052653,-2.05202791259183,1.3478444644435112,-0.1415423442786107,0.3341012059117994,0.38413580421459165,1.1620412739234138,0.5791408457585902,-0.39825124132052653,-0.19742355434165754
| 2,812
|
Mitochondrion organization
| 27
| 155
| 2.37646
| 0.01748
|
P30536,Q96CU9,Q9NS69,O75153,Q99595,O60830,P21796,P45880,Q5JRX3,Q16543,Q8N2A8,Q9Y512,O43676,Q96A26,Q9H061,O14737,P04062,Q9NUQ9,P30419,P42858,Q8N4H5,Q9Y6C9,O75306,P47985,Q6DKK2,Q9Y6M9,Q9Y2R0
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
0,4,5,7,8,9,13,17,157,289,164,165,39,296,48,175,87,89,98,228,235,244,115,236,121,258,126
|
1267,1702,594,175,516,720,2450,39,689,1428,9,7,2746,2357,115,1604,2133,2219,949,347,871,1548,1654,1486,2258,1029,1706,538,875,1385,1487,660,451,87,2175,1707,2221,808,1656,1868,2658,411,953,810,1186,13,2472,1919,1035,1660,98,0,2029,2474,1037,2087,2140,228,17,236,756,1133,1973,664,2089,1192,1975,386,2543,2545,503,2425,962,525,668,473,330,546,670,1201,764,1785,289,1991,2401,1249,932,850,1994,157,1205,392,1995,121,1678,2279,1307,2686,1459,768,604,2000,475,164,235,2370,531,2054,296,4,2114,830,1633,1796,633,2061,2751,8,2512,2630,858,306,708,2631,2754,2761,48,1165,1416,1417,1068,5,89,1172,2212,467,2411,1073,2704,1948,2351,714,1749,2127,126,497,1854,1539,657,536,1953,165,2688,244,258
|
-0.031687014709587694,-0.25395864506177507,0.45820991892635715,1.447902119529762,0.5552017244663052,0.3341012059117994,-0.7630370464216969,2.933293974683996,0.35918453124975014,-0.11384263369455079,4.51024026447363,4.529618358539734,-1.7358081894663777,-0.6692630532977037,1.8456202538155837,-0.19742355434165754,-0.48692821008242365,-0.5469546575117772,0.15470992714805706,0.8347092158473343,0.2066580696947229,-0.16940208304943802,-0.2256084890274861,-0.1415423442786107,-0.5772466087129535,0.10219020816314191,-0.25395864506177507,0.5311402316133299,0.2066580696947229,-0.08630127296868081,-0.1415423442786107,0.38413580421459165,0.6502352734037639,2.24427219514418,-0.5168492233508618,-0.25395864506177507,-0.5469546575117772,0.2580459451927195,-0.2256084890274861,-0.34001843888349026,-1.1570110616486227,0.7202683829276397,0.15470992714805706,0.2580459451927195,0.022313356391112545,3.948903861103401,-0.7946963348979321,-0.36904762138247893,0.10219020816314191,-0.2256084890274861,2.0753063950252693,5.472379812321296,-0.4276312314054814,-0.7946963348979321,0.10219020816314191,-0.457189555658307,-0.48692821008242365,1.2248145512604927,3.539634851198567,1.1830609814557924,0.3088845403658546,0.04908726812999223,-0.39825124132052653,0.38413580421459165,-0.457189555658307,0.022313356391112545,-0.39825124132052653,0.7663817253435458,-0.8909116443167836,-0.8909116443167836,0.5791408457585902,-0.7315799679422195,0.15470992714805706,0.5552017244663052,0.38413580421459165,0.6266565061101952,0.9020494934900769,0.5311402316133299,0.38413580421459165,0.022313356391112545,0.3088845403658546,-0.28247580804102473,1.0338708607112133,-0.39825124132052653,-0.7003227426014513,-0.004610885946918551,0.1807547309326192,0.23242134673518783,-0.39825124132052653,1.5263971248405028,0.022313356391112545,0.7663817253435458,-0.39825124132052653,1.8274547643749006,-0.2256084890274861,-0.5772466087129535,-0.031687014709587694,-1.260581097169132,-0.11384263369455079,0.3088845403658546,0.45820991892635715,-0.39825124132052653,0.6266565061101952,1.4873187834566612,1.2039851426447223,-0.6692630532977037,0.5552017244663052,-0.4276312314054814,1.012159267293361,4.773418117753822,-0.457189555658307,0.2580459451927195,-0.19742355434165754,-0.28247580804102473,0.43364725460652315,-0.4276312314054814,-1.7742810257372263,4.519940897786278,-0.8265602308855787,-1.0555468822980754,0.23242134673518783,0.9903454141911546,0.35918453124975014,-1.0555468822980754,-1.8914733252320852,-1.9711219201568242,2.7154898327425006,0.04908726812999223,-0.08630127296868081,-0.08630127296868081,0.10219020816314191,4.736858349607043,2.1942542072619107,0.04908726812999223,-0.5168492233508618,0.6502352734037639,-0.7003227426014513,0.10219020816314191,-1.4020919554916431,-0.36904762138247893,-0.6383986218099443,0.35918453124975014,-0.25395864506177507,-0.457189555658307,1.809215592081938,0.6029587324284209,-0.311161791776721,-0.1415423442786107,0.40895629462372546,0.5552017244663052,-0.36904762138247893,1.4873187834566612,-1.260581097169132,1.1830609814557924,1.1409252165655943
| 2,812
|
Secondary alcohol metabolic process
| 10
| 38
| 2.374032
| 0.017595
|
Q8WTV0,O75874,Q16850,Q15392,P48449,O15118,P04062,Q15800,P48735,Q9BQE5
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
37,135,69,10,142,82,87,152,57,158
|
82,1602,519,135,383,1704,2021,2770,87,1282,1284,583,2305,2755,444,2140,142,57,640,1880,1566,414,1670,2685,668,2426,506,232,2197,10,1935,152,69,37,2602,158,1372,2215
|
2.326399504773361,-0.19742355434165754,0.5552017244663052,1.6605823293503985,0.7663817253435458,-0.25395864506177507,-0.4276312314054814,-2.1342282062168807,2.24427219514418,-0.031687014709587694,-0.031687014709587694,0.4826455052953858,-0.6077272079458682,-1.9311426944841017,0.6736961261378334,-0.48692821008242365,1.6416545156496378,2.533032514844444,0.40895629462372546,-0.34001843888349026,-0.16940208304943802,0.7202683829276397,-0.2256084890274861,-1.260581097169132,0.38413580421459165,-0.7315799679422195,0.5791408457585902,1.2248145512604927,-0.5168492233508618,4.4515440828239035,-0.36904762138247893,1.565142433258028,2.4547035837208413,3.0312962380643427,-0.9890357013357498,1.5263971248405028,-0.05891660926003703,-0.5168492233508618
| 2,812
|
Cellular response to molecule of bacterial origin
| 9
| 25
| 2.370866
| 0.017746
|
P30536,Q16539,Q8WTV0,P14174,P08670,O43823,Q8IXJ6,Q9NUQ9,Q53EL6
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
0,550,37,260,385,166,508,89,447
|
166,385,2300,725,260,2589,2085,1769,0,1290,550,447,1677,855,1352,1519,1520,508,1103,37,2157,1841,89,1947,614
|
1.4676530771754677,0.7663817253435458,-0.6077272079458682,0.3341012059117994,1.119711996032066,-0.9890357013357498,-0.457189555658307,-0.28247580804102473,5.472379812321296,-0.031687014709587694,0.5311402316133299,0.6736961261378334,-0.2256084890274861,0.23242134673518783,-0.05891660926003703,-0.1415423442786107,-0.1415423442786107,0.5791408457585902,0.07571238201592677,3.0312962380643427,-0.48692821008242365,-0.311161791776721,2.1942542072619107,-0.36904762138247893,0.45820991892635715
| 2,812
|
Visual loss
| 9
| 44
| 2.366597
| 0.017952
|
P50897,P07602,O14773,P01889,P48449,O75306,Q8NHS3,O75503,P04439
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
68,101,100,167,142,115,20,21,160
|
2735,2257,1267,594,100,1428,115,2219,21,987,1654,1280,2469,167,451,2330,160,101,2359,1555,2262,1768,1291,2682,488,921,142,68,1397,1040,1044,525,2098,1508,1511,2102,2243,20,2406,532,201,633,2630,1020
|
-1.6597250820929819,-0.5772466087129535,-0.031687014709587694,0.45820991892635715,2.0407291615321252,-0.11384263369455079,1.8456202538155837,-0.5469546575117772,3.4527621477763786,0.1285222344905635,-0.2256084890274861,-0.031687014709587694,-0.7946963348979321,1.4676530771754677,0.6502352734037639,-0.6383986218099443,1.4873187834566612,2.0233395056563532,-0.6692630532977037,-0.16940208304943802,-0.5772466087129535,-0.28247580804102473,-0.031687014709587694,-1.260581097169132,0.6029587324284209,0.1807547309326192,1.6416545156496378,2.4547035837208413,-0.08630127296868081,0.10219020816314191,0.10219020816314191,0.5552017244663052,-0.457189555658307,-0.1415423442786107,-0.1415423442786107,-0.457189555658307,-0.5469546575117772,3.490212452974606,-0.7003227426014513,0.5552017244663052,1.3275674269755584,0.43364725460652315,-1.0555468822980754,0.1285222344905635
| 2,812
|
Regulation of immune response
| 37
| 112
| 2.365185
| 0.018021
|
Q9NQC3,Q5RKV6,Q9UKG1,P04083,O96028,P43243,Q14258,P04439,Q16543,Q16539,Q96FZ2,P01889,Q96FV9,Q9NZ08,P46379,P62942,Q14671,Q9NPR9,P46109,Q07666,O75179,P45985,Q9NUD5,P09601,Q96ST3,Q9NUQ9,P17931,Q06124,Q9H000,Q96IZ0,Q5KU26,Q06481,P28070,O94992,P19474,O43657,Q96PK6
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
266,391,409,269,147,522,547,160,289,550,172,167,434,438,46,302,428,54,445,316,195,322,203,79,478,89,469,95,367,366,490,111,110,482,116,370,256
|
1702,1024,1758,370,1761,195,2134,872,1548,482,147,167,660,269,160,1709,808,1387,2300,79,1657,2658,990,2571,2138,1814,469,1389,2644,116,1495,1714,1970,2085,110,1769,2474,1611,1089,522,957,322,445,46,887,1563,2035,1929,925,2611,302,787,667,95,111,790,316,1095,2044,2765,570,1301,1401,2547,1989,892,547,428,2102,1674,550,289,490,391,1937,2052,736,770,1462,1257,1211,2532,434,172,366,1902,256,2486,478,2061,2512,2160,367,1467,1166,54,266,1167,776,203,89,1641,1849,438,1264,2698,2489,744,1749,409,1856,1700
|
-0.25395864506177507,0.10219020816314191,-0.28247580804102473,0.789268883456853,-0.28247580804102473,1.3478444644435112,-0.48692821008242365,0.2066580696947229,-0.16940208304943802,0.6029587324284209,1.6035598788121985,1.4676530771754677,0.38413580421459165,1.098400788944567,1.4873187834566612,-0.25395864506177507,0.2580459451927195,-0.08630127296868081,-0.6077272079458682,2.342643329037244,-0.2256084890274861,-1.1570110616486227,0.1285222344905635,-0.9561113158015919,-0.48692821008242365,-0.311161791776721,0.6266565061101952,-0.08630127296868081,-1.1229595856058519,1.8456202538155837,-0.1415423442786107,-0.25395864506177507,-0.39825124132052653,-0.457189555658307,1.899680038524244,-0.28247580804102473,-0.7946963348979321,-0.19742355434165754,0.07571238201592677,0.5552017244663052,0.15470992714805706,0.9242813695324721,0.6736961261378334,2.759934875525814,0.2066580696947229,-0.16940208304943802,-0.4276312314054814,-0.36904762138247893,0.1807547309326192,-1.0221799869805437,0.9903454141911546,0.2835332284224711,0.38413580421459165,2.1096173622141015,1.899680038524244,0.2835332284224711,0.946407369350807,0.07571238201592677,-0.4276312314054814,-2.05202791259183,0.5069552146823165,-0.031687014709587694,-0.08630127296868081,-0.8909116443167836,-0.39825124132052653,0.2066580696947229,0.5311402316133299,0.6970401416277441,-0.457189555658307,-0.2256084890274861,0.5311402316133299,1.0338708607112133,0.6029587324284209,0.7663817253435458,-0.36904762138247893,-0.4276312314054814,0.3341012059117994,0.3088845403658546,-0.11384263369455079,-0.004610885946918551,0.022313356391112545,-0.858631173481535,0.6970401416277441,1.4676530771754677,0.8120443818425275,-0.34001843888349026,1.1409252165655943,-0.7946963348979321,0.6266565061101952,-0.4276312314054814,-0.8265602308855787,-0.48692821008242365,0.8120443818425275,-0.11384263369455079,0.04908726812999223,2.5639762514184214,1.119711996032066,0.04908726812999223,0.3088845403658546,1.3275674269755584,2.1942542072619107,-0.19742355434165754,-0.311161791776721,0.6970401416277441,-0.004610885946918551,-1.3663385868789217,-0.7946963348979321,0.3341012059117994,-0.25395864506177507,0.7433818990772783,-0.311161791776721,-0.2256084890274861
| 2,812
|
Disproportionate short stature
| 10
| 20
| 2.364503
| 0.018054
|
P16278,Q7LGA3,Q32P28,Q14739,O75718,Q15392,O00116,Q03164,Q9UHX1,P42345
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
161,416,96,232,259,10,449,24,319,501
|
449,1646,1649,259,520,161,2606,501,2265,24,232,2427,10,96,1008,416,706,2158,1372,319
|
0.6502352734037639,-0.2256084890274861,-0.2256084890274861,1.119711996032066,0.5552017244663052,1.4873187834566612,-1.0221799869805437,0.5791408457585902,-0.5772466087129535,3.389598452737596,1.2248145512604927,-0.7315799679422195,4.4515440828239035,2.0924949265029182,0.1285222344905635,0.7202683829276397,0.35918453124975014,-0.48692821008242365,-0.05891660926003703,0.946407369350807
| 2,812
|
Antigen processing cross presentation
| 13
| 47
| 2.358736
| 0.018337
|
P10321,P25788,P28074,Q99436,P20618,P01889,P28072,P28070,P49721,Q9UIQ6,P60900,P49720,P04439
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
312,292,70,199,102,167,45,110,18,25,120,314,160
|
2699,514,2072,1481,2383,1271,2758,347,167,160,2300,312,1917,102,1970,1558,292,1288,2180,1087,110,45,70,2182,1775,1131,845,314,18,2267,2716,120,568,1294,926,1666,1139,1449,2765,2272,1148,1149,199,1531,25,512,1643
|
-1.4020919554916431,0.5552017244663052,-0.457189555658307,-0.1415423442786107,-0.7003227426014513,-0.031687014709587694,-1.9711219201568242,0.8347092158473343,1.4676530771754677,1.4873187834566612,-0.6077272079458682,0.946407369350807,-0.36904762138247893,2.005881846159429,-0.39825124132052653,-0.16940208304943802,1.012159267293361,-0.031687014709587694,-0.5168492233508618,0.07571238201592677,1.899680038524244,2.759934875525814,2.4229764762472206,-0.5168492233508618,-0.28247580804102473,0.04908726812999223,0.23242134673518783,0.946407369350807,3.539634851198567,-0.5772466087129535,-1.4743698115558657,1.8274547643749006,0.5069552146823165,-0.031687014709587694,0.1807547309326192,-0.2256084890274861,0.04908726812999223,-0.11384263369455079,-2.05202791259183,-0.5772466087129535,0.04908726812999223,0.04908726812999223,1.3478444644435112,-0.1415423442786107,3.376851885313292,0.5791408457585902,-0.19742355434165754
| 2,812
|
Increased intracranial pressure
| 9
| 17
| 2.357544
| 0.018396
|
P21912,P07602,P52701,P01889,Q969G3,Q9NZ08,P49327,Q15437,P10644
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
196,101,600,167,201,438,585,114,520
|
167,101,520,196,1291,957,585,1565,600,2310,1508,114,965,201,633,438,1020
|
1.4676530771754677,2.0233395056563532,0.5552017244663052,1.3478444644435112,-0.031687014709587694,0.15470992714805706,0.4826455052953858,-0.16940208304943802,0.45820991892635715,-0.6077272079458682,-0.1415423442786107,1.8637126046605421,0.15470992714805706,1.3275674269755584,0.43364725460652315,0.6970401416277441,0.1285222344905635
| 2,812
|
Malignant neoplasm of the central nervous system
| 6
| 20
| 2.342412
| 0.01916
|
P21912,Q15555,O75874,P07437,P48735,Q06124
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
196,197,135,246,57,95
|
870,135,876,1707,246,1767,1768,196,1291,957,57,600,2310,95,1508,197,965,1843,344,496
|
0.2066580696947229,1.6605823293503985,0.2066580696947229,-0.25395864506177507,1.1620412739234138,-0.28247580804102473,-0.28247580804102473,1.3478444644435112,-0.031687014709587694,0.15470992714805706,2.533032514844444,0.45820991892635715,-0.6077272079458682,2.1096173622141015,-0.1415423442786107,1.3478444644435112,0.15470992714805706,-0.311161791776721,0.8572643679612094,0.6029587324284209
| 2,812
|
Tetrapyrrole binding
| 6
| 14
| 2.338889
| 0.019341
|
Q16850,P09601,Q8WUJ1,O15173,Q9H7Z7,P30519
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
69,79,81,51,125,30
|
282,51,127,2419,79,2724,30,69,1009,81,2159,125,2487,2688
|
1.0554810704738096,2.6252145052389237,1.7909021867676338,-0.7315799679422195,2.342643329037244,-1.54769869262779,3.247236697579701,2.4547035837208413,0.1285222344905635,2.342643329037244,-0.48692821008242365,1.809215592081938,-0.7946963348979321,-1.260581097169132
| 2,812
|
nuclear_membrane
| 8
| 33
| 2.337863
| 0.019394
|
P55735,O00505,Q9H074,Q14739,O00629,P52294,O60684,P57740
|
Localization
|
OpenCell Localization
|
opencell_localization
|
129,31,264,232,42,43,185,284
|
31,42,1546,185,2134,950,1487,1556,1388,2456,1875,599,1718,1663,960,923,43,2233,129,284,2038,2424,232,1051,1515,1356,2779,295,1903,264,1748,1423,2015
|
3.16753088514317,2.803929621091696,-0.16940208304943802,1.3881308939912163,-0.48692821008242365,0.15470992714805706,-0.1415423442786107,-0.16940208304943802,-0.08630127296868081,-0.7630370464216969,-0.34001843888349026,0.45820991892635715,-0.25395864506177507,-0.2256084890274861,0.15470992714805706,0.1807547309326192,2.789314221988835,-0.5469546575117772,1.7168950201979138,1.0554810704738096,-0.4276312314054814,-0.7315799679422195,1.2248145512604927,0.10219020816314191,-0.1415423442786107,-0.05891660926003703,-2.388988446943391,1.012159267293361,-0.34001843888349026,1.119711996032066,-0.25395864506177507,-0.08630127296868081,-0.39825124132052653
| 2,812
|
Amide binding
| 33
| 99
| 2.336407
| 0.01947
|
Q15392,P55786,P21796,P45880,Q96AY3,Q6P179,Q9UIQ6,O00264,P04439,O00505,P55899,Q01650,Q8WTV0,Q9Y287,Q92973,O00629,P52294,P01889,Q9NZ08,P21266,P62942,O60684,P61758,P10321,Q9UHB9,Q9NXR7,P42892,O14773,P07602,P00374,Q07954,Q9H7Z7,Q9BYT8
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
10,386,13,17,405,279,25,282,160,31,163,415,37,174,295,42,43,167,438,177,302,185,446,312,334,210,86,100,101,245,374,125,397
|
2172,282,909,31,42,2809,100,517,1912,518,185,659,1548,245,167,160,748,2806,101,1553,1387,2633,1031,312,2807,1085,177,13,1968,2606,2264,2180,885,1660,442,565,1875,2390,521,921,86,1821,17,1500,585,640,1663,960,2476,2660,923,43,2233,386,163,2528,1294,446,302,1983,2396,415,788,2189,374,1827,1931,1345,2193,1051,1572,764,10,2752,279,1358,37,934,295,405,2409,2802,652,2512,2119,397,1469,654,125,1416,552,210,438,1020,334,1021,25,174,1424
|
-0.5168492233508618,1.0554810704738096,0.1807547309326192,3.16753088514317,2.803929621091696,-6.361998059528838,2.0407291615321252,0.5552017244663052,-0.36904762138247893,0.5552017244663052,1.3881308939912163,0.38413580421459165,-0.16940208304943802,1.1620412739234138,1.4676530771754677,1.4873187834566612,0.3088845403658546,-4.763012016679032,2.0233395056563532,-0.16940208304943802,-0.08630127296868081,-1.0891391456991428,0.10219020816314191,0.946407369350807,-5.183160626066443,0.07571238201592677,1.447902119529762,3.948903861103401,-0.39825124132052653,-1.0221799869805437,-0.5772466087129535,-0.5168492233508618,0.2066580696947229,-0.2256084890274861,0.6736961261378334,0.5069552146823165,-0.34001843888349026,-0.7003227426014513,0.5552017244663052,0.1807547309326192,2.2608201286194824,-0.311161791776721,3.539634851198567,-0.1415423442786107,0.4826455052953858,0.40895629462372546,-0.2256084890274861,0.15470992714805706,-0.7946963348979321,-1.1570110616486227,0.1807547309326192,2.789314221988835,-0.5469546575117772,0.7663817253435458,1.4873187834566612,-0.858631173481535,-0.031687014709587694,0.6736961261378334,0.9903454141911546,-0.39825124132052653,-0.7003227426014513,0.7202683829276397,0.2835332284224711,-0.5168492233508618,0.789268883456853,-0.311161791776721,-0.36904762138247893,-0.05891660926003703,-0.5168492233508618,0.10219020816314191,-0.16940208304943802,0.3088845403658546,4.4515440828239035,-1.85210943491167,1.0769907617339176,-0.05891660926003703,3.0312962380643427,0.1807547309326192,1.012159267293361,0.7433818990772783,-0.7003227426014513,-4.185544459405158,0.40895629462372546,-0.8265602308855787,-0.457189555658307,0.7663817253435458,-0.11384263369455079,0.40895629462372546,1.809215592081938,-0.08630127296868081,0.5311402316133299,1.3072002040011301,0.6970401416277441,0.1285222344905635,0.9020494934900769,0.1285222344905635,3.376851885313292,1.4676530771754677,-0.08630127296868081
| 2,812
|
Signal sequence binding
| 6
| 24
| 2.335281
| 0.019529
|
O00505,Q92973,O00629,P52294,Q9NXR7,O60684
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
31,295,42,43,210,185
|
909,31,42,185,1548,1875,2390,521,1663,923,43,2233,2528,1294,1983,1051,1572,764,1358,295,2409,2119,210,334
|
0.1807547309326192,3.16753088514317,2.803929621091696,1.3881308939912163,-0.16940208304943802,-0.34001843888349026,-0.7003227426014513,0.5552017244663052,-0.2256084890274861,0.1807547309326192,2.789314221988835,-0.5469546575117772,-0.858631173481535,-0.031687014709587694,-0.39825124132052653,0.10219020816314191,-0.16940208304943802,0.3088845403658546,-0.05891660926003703,1.012159267293361,-0.7003227426014513,-0.457189555658307,1.3072002040011301,0.9020494934900769
| 2,812
|
Host interactions of hiv factors
| 21
| 92
| 2.325365
| 0.020052
|
Q15369,P55735,Q99567,P49721,P57740,P04439,P25788,P52294,P28072,P49720,Q9BW27,P28074,Q99436,O75832,Q9BTX1,P20618,Q8NFH4,P28070,Q9UL46,P60900,Q12769
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
253,129,533,18,284,160,292,43,45,314,466,70,199,347,494,102,240,110,512,120,505
|
514,2072,1481,2383,1546,910,1271,1761,2417,2134,950,347,1549,2759,160,2221,2222,953,1434,1388,1712,1917,1967,102,1970,1558,292,1288,1087,110,45,70,1875,1775,1235,1777,1131,1395,845,314,18,1663,960,2267,43,2233,2634,129,284,120,568,926,1666,1139,2424,1400,1983,666,2395,1449,1046,505,1401,2272,1051,1148,1149,253,1729,1204,1578,971,1898,240,1793,1311,1413,2484,2409,2463,199,1531,533,494,2119,466,1017,1744,1223,1373,512,1643
|
0.5552017244663052,-0.457189555658307,-0.1415423442786107,-0.7003227426014513,-0.16940208304943802,0.1807547309326192,-0.031687014709587694,-0.28247580804102473,-0.7315799679422195,-0.48692821008242365,0.15470992714805706,0.8347092158473343,-0.16940208304943802,-1.9711219201568242,1.4873187834566612,-0.5469546575117772,-0.5469546575117772,0.15470992714805706,-0.11384263369455079,-0.08630127296868081,-0.25395864506177507,-0.36904762138247893,-0.39825124132052653,2.005881846159429,-0.39825124132052653,-0.16940208304943802,1.012159267293361,-0.031687014709587694,0.07571238201592677,1.899680038524244,2.759934875525814,2.4229764762472206,-0.34001843888349026,-0.28247580804102473,-0.004610885946918551,-0.28247580804102473,0.04908726812999223,-0.08630127296868081,0.23242134673518783,0.946407369350807,3.539634851198567,-0.2256084890274861,0.15470992714805706,-0.5772466087129535,2.789314221988835,-0.5469546575117772,-1.0891391456991428,1.7168950201979138,1.0554810704738096,1.8274547643749006,0.5069552146823165,0.1807547309326192,-0.2256084890274861,0.04908726812999223,-0.7315799679422195,-0.08630127296868081,-0.39825124132052653,0.38413580421459165,-0.7003227426014513,-0.11384263369455079,0.10219020816314191,0.5791408457585902,-0.08630127296868081,-0.5772466087129535,0.10219020816314191,0.04908726812999223,0.04908726812999223,1.1409252165655943,-0.25395864506177507,0.022313356391112545,-0.16940208304943802,0.15470992714805706,-0.34001843888349026,1.1830609814557924,-0.28247580804102473,-0.031687014709587694,-0.08630127296868081,-0.7946963348979321,-0.7003227426014513,-0.7630370464216969,1.3478444644435112,-0.1415423442786107,0.5552017244663052,0.6029587324284209,-0.457189555658307,0.6502352734037639,0.1285222344905635,-0.25395864506177507,0.022313356391112545,-0.05891660926003703,0.5791408457585902,-0.19742355434165754
| 2,812
|
Insulin receptor signaling pathway
| 9
| 24
| 2.322835
| 0.020188
|
P31751,Q9Y5X3,Q9BZF1,Q9UKG1,P43490,Q9HCD5,Q9UQB8,Q92572,Q06124
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
227,439,307,409,49,480,22,255,95
|
1269,839,1757,1866,1709,1553,725,1085,1389,227,49,523,95,668,2579,2057,255,1314,2532,307,480,409,22,439
|
-0.031687014709587694,0.23242134673518783,-0.28247580804102473,-0.34001843888349026,-0.25395864506177507,-0.16940208304943802,0.3341012059117994,0.07571238201592677,-0.08630127296868081,1.2248145512604927,2.655514539093404,0.5552017244663052,2.1096173622141015,0.38413580421459165,-0.9561113158015919,-0.4276312314054814,1.1409252165655943,-0.031687014709587694,-0.858631173481535,0.9903454141911546,0.6266565061101952,0.7433818990772783,3.427609667571787,0.6970401416277441
| 2,812
|
Intrinsic component of organelle membrane
| 82
| 131
| 5.579451
| 0
|
O60830,Q99595,Q96AQ8,Q9NPA0,Q9Y2R0,Q6UXV4,Q9Y282,Q9HCU5,O14975,Q9H4I9,Q9GZY8,P12235,O15258,O43505,Q15629,Q9UM00,Q9NZ01,O43819,P42892,Q9UG56,O75844,Q96ER9,Q8TB61,Q8TB36,O15118,Q13505,Q14739,Q8TCT9,Q9UH99,Q86XL3,Q13586,Q15006,Q15070,O14925,Q16891,O94901,Q9Y4P3,Q9NXW2,Q9NQC3,P20020,O75431,O15126,P13473,O95470,P61020,P04439,P57105,Q96A33,Q9BUN8,Q8IXI1,Q5HYI7,Q9P035,Q9H9B4,Q5XKP0,Q9H9P8,O95070,Q9Y679,Q9H490,O94826,Q03519,P56589,Q6P4A7,P57088,P10321,Q8IWA4,Q9BPX6,Q86Y82,Q9UBM7,Q9Y512,P51572,Q8N8Q8,Q9H3K2,O96008,Q96NB2,Q9NX63,Q8N2H4,O75880,Q9BUB7,Q9HC21,Q12981,Q99442,Q15041
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
0,3,514,524,11,519,17,533,526,24,544,553,558,559,51,576,63,563,68,69,73,594,83,604,91,104,614,113,642,123,633,648,143,146,661,657,678,688,169,683,681,680,187,194,705,703,209,211,216,743,223,240,769,244,770,248,773,768,757,261,273,290,308,323,327,343,357,366,367,377,389,397,399,413,445,450,463,469,488,494,503,499
|
1121,753,146,526,91,680,558,1053,1560,559,950,563,0,965,681,73,463,757,657,248,835,194,1463,399,1127,703,323,553,187,683,1144,820,2745,1222,1668,2415,68,893,1295,970,1739,377,273,308,209,705,912,913,261,1676,494,104,633,1105,614,648,499,143,2294,51,934,661,827,223,1268,794,244,290,519,1087,2081,123,357,327,898,743,1111,450,1276,389,1681,1580,604,83,113,997,1538,831,211,514,594,413,1412,503,3,343,2012,832,469,216,1243,544,397,768,24,769,770,488,533,524,169,1007,1030,445,688,63,240,2402,366,69,799,642,576,17,11,1252,678,865,367,948,773
|
0.06706796620069248,0.36281679569392605,1.950506657749701,0.6414242418555797,2.449071204722446,0.43772031258177796,0.5984987511004508,0.11498437510700303,-0.17986003989876528,0.5984987511004508,0.19380682512269046,0.5841039652256301,4.125669255470878,0.17814470796339205,0.43772031258177796,2.71093528756688,0.7540350803801485,0.36281679569392605,0.4673573625937165,1.390659754720825,0.2867278246330759,1.6619426173233864,-0.1294642520833557,0.8776079734066499,0.06706796620069248,0.4078989792455411,1.11545308586704,0.6128502332132403,1.7301647060416219,0.43772031258177796,0.05099010895251097,0.30204211533490194,-0.847927384389837,0.002434827265685641,-0.23078025553282336,-0.6212288478544631,2.7561169853489744,0.2404909124205327,-0.030206765888258928,0.17814470796339205,-0.26502341218255865,0.931509813270278,1.280029869062608,1.1411524269414506,1.5810509907278525,0.4078989792455411,0.22497962854566572,0.22497962854566572,1.3418152746816723,-0.23078025553282336,0.7121179729480956,2.351702020702256,0.4968122165583206,0.08309274884485632,0.5260869274788118,0.4821074349746622,0.6980630201166272,1.9719673804988322,-0.5479033919239744,2.9409961260648005,0.2094183652836215,0.4673573625937165,0.30204211533490194,1.5105686587244185,-0.013858605375158513,0.33252539041368356,1.4027910875879954,1.2300052027613868,0.655647241447091,0.09906477879078189,-0.42214155708180023,2.129773251435637,0.9980324104770499,1.0896121215347725,0.2404909124205327,0.37789124027862775,0.08309274884485632,0.781775583130449,-0.013858605375158513,0.9046357978310428,-0.23078025553282336,-0.17986003989876528,0.5406573616707142,2.525471026963564,2.2521766001450425,0.16243171108876198,-0.16300366701431568,0.30204211533490194,1.5693783522525775,0.669827883440752,0.5551835148202413,0.836774272954116,-0.09615352598164383,0.6980630201166272,4.125669255470878,1.0505819654024655,-0.3867903586863053,0.30204211533490194,0.7540350803801485,1.5576761325356283,0.002434827265685641,0.6271586509706826,0.8911412130144085,0.36281679569392605,3.475941491201594,0.36281679569392605,0.36281679569392605,0.7261314845184232,0.6414242418555797,0.655647241447091,1.8306337022721588,0.16243171108876198,0.14666752913432865,0.7955852218137351,0.43772031258177796,2.78300653577057,1.4389960408956042,-0.6027955681655673,0.9582316246880604,2.7561169853489744,0.33252539041368356,0.4968122165583206,0.5841039652256301,3.544036436727491,3.677076391361871,0.002434827265685641,0.45256174173642805,0.2713647192914942,0.9582316246880604,0.2094183652836215,0.36281679569392605
| 3,069
|
Transporter activity
| 88
| 176
| 4.859059
| 0.000001
|
O60830,Q99595,Q9NS69,Q8TDW0,P45880,Q9Y6M7,Q8WTV0,Q9UGP8,P21796,Q8NE01,O14975,Q9C0H2,Q6NT16,Q9UJS0,Q9Y584,Q96ES6,P51991,P13073,O43676,Q70HW3,P12235,P00846,P04062,Q9Y487,P30536,Q9UM00,Q9UBX3,Q9UDW1,Q8TAD4,Q9HD20,P12236,Q99567,Q9BQT8,Q96ER9,O95168,Q8TB61,O95202,O15118,O75964,Q8IXU6,Q15758,Q8NEW0,P00403,O15173,O43772,P17900,P30825,Q96GC9,Q9H2V7,Q9Y619,Q9Y277,O14925,P08183,Q9Y6M9,Q93050,P38435,P35670,P53985,Q9H2J7,O96000,P49755,Q9H4L5,P03915,P16615,Q9Y5J9,Q03519,P41440,Q9P0J0,O15439,Q9NW15,Q7Z3C6,Q99797,Q6P4A7,O43681,P39210,Q6P4Q7,Q7KZN9,P51790,Q15043,O96008,P05023,Q96NB2,Q6NUK1,O75306,P24539,Q96AA3,Q9HC21,Q5BJD5
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
0,3,4,522,8,536,16,534,15,530,526,26,27,547,32,33,539,538,38,39,553,42,45,562,53,576,56,57,60,61,565,585,75,594,590,83,591,91,93,95,617,101,108,109,116,117,120,124,126,131,138,146,152,161,163,174,195,202,204,225,228,237,242,249,258,261,269,271,278,281,284,286,290,298,300,320,331,329,352,399,404,413,441,437,448,486,488,484
|
753,679,1944,700,1218,146,526,91,109,278,1945,38,1288,298,116,950,0,1013,1836,437,2312,1429,1125,1520,93,757,590,591,1947,1463,225,399,108,42,242,45,404,1098,1054,908,1195,721,152,909,910,3028,1167,3051,553,565,538,249,117,2132,683,778,1365,2743,15,1145,448,1956,836,2899,53,120,1315,195,928,1078,174,2678,300,269,8,969,2865,1058,228,2797,329,1568,1434,539,1178,1262,202,1338,1059,840,1180,912,913,1644,261,2987,1208,1374,879,880,352,617,881,2519,626,484,618,27,441,1926,290,320,39,331,284,898,95,996,530,1580,101,60,83,522,16,2363,163,486,594,33,124,413,665,3048,2180,585,3,286,731,2338,75,834,2493,2937,26,712,204,126,237,769,488,61,1007,4,698,281,271,56,57,534,1939,547,576,2404,716,138,1458,562,32,258,752,131,2895,1389,536,161
|
0.36281679569392605,0.43772031258177796,-0.3692094267674327,0.4078989792455411,0.002434827265685641,1.950506657749701,0.6414242418555797,2.449071204722446,2.3220747758671,1.2550845585859318,-0.3692094267674327,3.143192229979514,-0.030206765888258928,1.1794390031101867,2.2218852461661323,0.19380682512269046,4.125669255470878,0.14666752913432865,-0.3168403575565848,0.7955852218137351,-0.5661333020712928,-0.11278048268758513,0.06706796620069248,-0.16300366701431568,2.449071204722446,0.36281679569392605,0.5551835148202413,0.5551835148202413,-0.3692094267674327,-0.1294642520833557,1.4987164375383368,0.8776079734066499,2.3319722280450734,3.034827813634531,1.4269590798007796,3.017915919263261,0.8640358745112992,0.08309274884485632,0.11498437510700303,0.22497962854566572,0.018673868634717674,0.39291854449948976,1.9072797273295248,0.22497962854566572,0.22497962854566572,-1.6871559429488037,0.0348588523240148,-2.421230489514741,0.6128502332132403,0.5841039652256301,0.6271586509706826,1.390659754720825,2.2218852461661323,-0.45774800066276633,0.43772031258177796,0.3476949375688096,-0.07958302654545266,-0.847927384389837,3.551536551149184,0.05099010895251097,0.781775583130449,-0.3692094267674327,0.2867278246330759,-1.0853969322237222,2.915054362320261,2.1709437111682344,-0.04660999391817365,1.6619426173233864,0.2094183652836215,0.09906477879078189,1.8084968281201592,-0.79027866305354,1.1794390031101867,1.304842448283804,3.7990432016623545,0.17814470796339205,-1.0049855843887756,0.11498437510700303,1.4868337902652249,-0.9062487336772611,1.0766380800365236,-0.17986003989876528,-0.11278048268758513,0.6271586509706826,0.0348588523240148,-0.013858605375158513,1.6158927888366963,-0.06306863218986276,0.11498437510700303,0.2867278246330759,0.0348588523240148,0.22497962854566572,0.22497962854566572,-0.21374796024844483,1.3418152746816723,-1.313376008354104,0.018673868634717674,-0.07958302654545266,0.255952511861343,0.255952511861343,1.0243805753397968,0.5260869274788118,0.255952511861343,-0.6769429135129599,0.5114719629049498,0.7261314845184232,0.5260869274788118,3.3285620139858545,0.7955852218137351,-0.3516910545716578,1.2300052027613868,1.1283203698531714,3.0768243981140175,1.0766380800365236,1.242561719212632,0.2404909124205327,2.439428869539286,0.16243171108876198,0.6414242418555797,-0.17986003989876528,2.3615345361909066,2.818607017092348,2.525471026963564,0.655647241447091,3.544036436727491,-0.5844305409591135,1.863639502869007,0.7261314845184232,0.5551835148202413,3.2328322525717677,2.129773251435637,0.836774272954116,0.4673573625937165,-2.2404424083131307,-0.4756480043806108,0.5696656342376731,4.125669255470878,1.242561719212632,0.39291854449948976,-0.5661333020712928,2.6836037582923837,0.30204211533490194,-0.6583020446262418,-1.1671130876239315,3.344313892455025,0.4078989792455411,1.6043080729323946,2.1090467965731245,1.4510018447343276,0.36281679569392605,0.7261314845184232,2.8008425897497315,0.16243171108876198,4.125669255470878,0.4228328131433475,1.2550845585859318,1.2924526686835236,2.8451205119843253,2.8451205119843253,0.6414242418555797,-0.3516910545716578,0.6271586509706826,0.5841039652256301,-0.6027955681655673,0.4078989792455411,2.0145877281129803,-0.11278048268758513,0.5984987511004508,3.248934240656014,1.366301653124708,0.37789124027862775,2.0462929128969036,-1.065173276993352,-0.07958302654545266,0.6414242418555797,1.8745887034572348
| 3,069
|
Protein localization
| 34
| 77
| 4.394064
| 0.000011
|
O60830,Q99595,Q9NS69,P51648,Q9Y5J9,O15254,Q9NR77,P21796,O96008,P56589,O14925,Q15067,Q8N4H5,Q8N4Q1,Q9Y584,Q13011,P62072,Q13190,O43681,Q96B49,P39210,Q5JRX3,Q10713,P46379,P50402,P40855,O60220,P09601,O00116,Q13505,P34913,O75381,Q9Y512,Q9BY49
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
0,3,4,128,258,263,12,15,399,273,146,409,25,412,32,159,35,429,298,44,300,431,177,185,317,316,335,88,218,104,362,361,367,121
|
218,690,146,526,818,263,1096,298,925,950,335,0,361,2774,681,1428,1633,1125,1126,757,399,908,910,2675,88,2162,553,565,966,15,1636,1956,836,362,2351,2415,300,316,185,893,317,128,1261,273,2069,35,177,159,429,104,409,541,431,764,1479,25,412,996,604,2712,44,3,2820,675,121,1136,12,4,445,1307,547,964,1982,367,32,258,948
|
1.5341823947732471,0.4228328131433475,1.950506657749701,0.6414242418555797,0.30204211533490194,1.317199369207603,0.08309274884485632,1.1794390031101867,0.2094183652836215,0.19380682512269046,1.0505819654024655,4.125669255470878,0.97153594878527,-0.8867326554727312,0.43772031258177796,-0.11278048268758513,-0.21374796024844483,0.06706796620069248,0.06706796620069248,0.36281679569392605,0.8776079734066499,0.22497962854566572,0.22497962854566572,-0.79027866305354,2.4874342296963574,-0.4756480043806108,0.6128502332132403,0.5841039652256301,0.17814470796339205,3.551536551149184,-0.21374796024844483,-0.3692094267674327,0.2867278246330759,0.97153594878527,-0.5844305409591135,-0.6212288478544631,1.1794390031101867,1.1283203698531714,1.7414372304609023,0.2404909124205327,1.1283203698531714,2.056812333710736,-0.013858605375158513,1.280029869062608,-0.42214155708180023,3.2085671141055583,1.7862524375899929,1.8745887034572348,0.8093547404733235,2.351702020702256,0.8504247102515363,0.6271586509706826,0.8093547404733235,0.36281679569392605,-0.1294642520833557,3.445328693074278,0.836774272954116,0.16243171108876198,0.5406573616707142,-0.8094210498506128,3.026380013898526,4.125669255470878,-0.9258411670371093,0.45256174173642805,2.1606861561903865,0.06706796620069248,3.6331860602374753,4.125669255470878,0.7955852218137351,-0.030206765888258928,0.6271586509706826,0.19380682512269046,-0.3692094267674327,0.9582316246880604,3.248934240656014,1.366301653124708,0.2094183652836215
| 3,069
|
Lysosomal lumen
| 23
| 32
| 4.293059
| 0.000018
|
P11117,Q13510,P50897,P10619,Q8NHP8,O00584,Q14108,P06280,O43681,P04062,P38435,Q9UMR5,P07602,P15586,P13473,O14773,P16278,P10253,P38571,P54802,Q8IV08,P17900,Q9NZJ7
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
133,139,13,20,31,289,37,295,298,45,174,46,48,303,187,67,203,85,221,222,99,117,256
|
289,1559,67,298,45,658,295,328,48,775,2315,454,85,20,133,2791,187,303,203,117,174,221,13,222,139,37,99,1089,31,979,256,46
|
1.2300052027613868,-0.17986003989876528,2.7650983212483924,1.1794390031101867,3.017915919263261,0.4673573625937165,1.1921319124623524,1.0766380800365236,2.9924252844164885,0.3476949375688096,-0.5661333020712928,0.7679256085196353,2.5064930869004933,3.506338746109396,2.025180715051222,-0.9062487336772611,1.7301647060416219,1.16671156823295,1.6043080729323946,2.2218852461661323,1.8084968281201592,1.5223905970530132,3.6110714012320395,1.5223905970530132,1.9933274484979564,3.176002075643978,2.3811352391695215,0.09906477879078189,3.248934240656014,0.17814470796339205,1.3784966610797764,3.017915919263261
| 3,069
|
Ion transmembrane transporter activity
| 49
| 105
| 4.270961
| 0.000019
|
Q9Y619,Q8TDW0,P45880,Q9Y277,P41440,Q9Y6M7,P21796,P05023,O15439,Q9NW15,Q9C0H2,Q9UJS0,Q96NB2,Q6P4A7,Q96ES6,Q93050,P13073,Q70HW3,P12235,P00846,O43681,Q9Y487,Q9UM00,Q9UBX3,Q9UDW1,Q6NUK1,Q8TAD4,Q9HD20,P12236,Q6P4Q7,P24539,P35670,Q7KZN9,P53985,Q9BQT8,Q9H2J7,P51790,Q96ER9,Q8TB61,O95202,O75964,Q15043,Q15758,Q8NEW0,Q9HC21,P00403,O43772,P30825,P16615
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
131,522,8,138,269,536,15,404,278,281,26,547,413,290,33,163,538,39,553,42,298,562,576,56,57,441,60,61,565,320,448,195,331,202,75,204,329,594,83,591,93,352,617,101,488,108,116,120,249
|
1944,700,278,298,116,950,1125,1520,93,591,1463,108,42,404,1098,1054,908,1195,721,909,910,3028,1167,3051,553,565,538,249,683,778,1365,2743,15,448,1956,120,1315,195,928,1078,2678,269,8,969,2865,329,1568,1262,202,1338,1059,840,1180,912,913,1644,1208,879,880,352,617,626,618,441,1926,290,320,39,331,898,1580,101,60,83,522,2363,163,594,33,413,665,3048,731,75,834,26,712,204,769,488,61,281,56,57,1939,547,576,138,1458,562,752,131,2895,1389,536
|
-0.3692094267674327,0.4078989792455411,1.2550845585859318,1.1794390031101867,2.2218852461661323,0.19380682512269046,0.06706796620069248,-0.16300366701431568,2.449071204722446,0.5551835148202413,-0.1294642520833557,2.3319722280450734,3.034827813634531,0.8640358745112992,0.08309274884485632,0.11498437510700303,0.22497962854566572,0.018673868634717674,0.39291854449948976,0.22497962854566572,0.22497962854566572,-1.6871559429488037,0.0348588523240148,-2.421230489514741,0.6128502332132403,0.5841039652256301,0.6271586509706826,1.390659754720825,0.43772031258177796,0.3476949375688096,-0.07958302654545266,-0.847927384389837,3.551536551149184,0.781775583130449,-0.3692094267674327,2.1709437111682344,-0.04660999391817365,1.6619426173233864,0.2094183652836215,0.09906477879078189,-0.79027866305354,1.304842448283804,3.7990432016623545,0.17814470796339205,-1.0049855843887756,1.0766380800365236,-0.17986003989876528,-0.013858605375158513,1.6158927888366963,-0.06306863218986276,0.11498437510700303,0.2867278246330759,0.0348588523240148,0.22497962854566572,0.22497962854566572,-0.21374796024844483,0.018673868634717674,0.255952511861343,0.255952511861343,1.0243805753397968,0.5260869274788118,0.5114719629049498,0.5260869274788118,0.7955852218137351,-0.3516910545716578,1.2300052027613868,1.1283203698531714,3.0768243981140175,1.0766380800365236,0.2404909124205327,-0.17986003989876528,2.3615345361909066,2.818607017092348,2.525471026963564,0.655647241447091,-0.5844305409591135,1.863639502869007,0.5551835148202413,3.2328322525717677,0.836774272954116,0.4673573625937165,-2.2404424083131307,0.39291854449948976,2.6836037582923837,0.30204211533490194,3.344313892455025,0.4078989792455411,1.6043080729323946,0.36281679569392605,0.7261314845184232,2.8008425897497315,1.2550845585859318,2.8451205119843253,2.8451205119843253,-0.3516910545716578,0.6271586509706826,0.5841039652256301,2.0145877281129803,-0.11278048268758513,0.5984987511004508,0.37789124027862775,2.0462929128969036,-1.065173276993352,-0.07958302654545266,0.6414242418555797
| 3,069
|
Lysosome
| 24
| 50
| 4.26967
| 0.00002
|
P11117,Q15904,Q8NCC3,Q13510,P50897,P10619,Q93050,Q14108,P06280,O43681,P04062,Q9UMR5,P07602,P15586,O75503,P13473,O14773,P16278,P10253,O15118,P38571,P54802,P17900,Q9NZJ7
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
133,266,135,139,13,20,163,37,295,298,45,46,48,303,58,187,67,203,85,91,221,222,117,256
|
2942,1559,2373,67,91,298,2695,58,45,658,295,328,48,775,454,2063,1396,85,20,133,374,722,187,303,203,117,1604,221,13,2259,222,2874,1180,2512,1102,139,37,266,135,859,163,421,1028,256,1939,987,2870,46,771,562
|
-1.2084727595847877,-0.17986003989876528,-0.6027955681655673,2.7650983212483924,2.449071204722446,1.1794390031101867,-0.8094210498506128,2.8363003459677576,3.017915919263261,0.4673573625937165,1.1921319124623524,1.0766380800365236,2.9924252844164885,0.3476949375688096,0.7679256085196353,-0.42214155708180023,-0.09615352598164383,2.5064930869004933,3.506338746109396,2.025180715051222,0.931509813270278,0.39291854449948976,1.7301647060416219,1.16671156823295,1.6043080729323946,2.2218852461661323,-0.1967746802526644,1.5223905970530132,3.6110714012320395,-0.529740355465412,1.5223905970530132,-1.0249681947485962,0.0348588523240148,-0.6769429135129599,0.08309274884485632,1.9933274484979564,3.176002075643978,1.317199369207603,2.025180715051222,0.2713647192914942,1.863639502869007,0.8230843533330983,0.14666752913432865,1.3784966610797764,-0.3516910545716578,0.17814470796339205,-1.0049855843887756,3.017915919263261,0.36281679569392605,0.5984987511004508
| 3,069
|
Membrane lipid metabolic process
| 19
| 36
| 4.211207
| 0.000025
|
Q8NCC3,Q13510,P50897,Q99805,P06280,Q06136,P04062,P07602,Q9NZ01,O95470,Q8NBX0,P16278,P06865,O15121,Q96G23,P27544,Q9P035,P17900,Q9NZJ7
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
135,139,13,277,295,167,45,48,63,194,197,203,328,205,86,106,240,117,256
|
205,383,1601,1053,1255,194,45,658,295,328,48,775,203,117,1145,106,1172,13,877,167,139,808,827,197,135,1538,86,1412,653,277,768,986,63,256,240,1307
|
1.5926941854384824,0.9180919307885846,-0.1967746802526644,0.11498437510700303,-0.013858605375158513,1.6619426173233864,3.017915919263261,0.4673573625937165,1.1921319124623524,1.0766380800365236,2.9924252844164885,0.3476949375688096,1.6043080729323946,2.2218852461661323,0.05099010895251097,2.341847947069304,0.0348588523240148,3.6110714012320395,0.255952511861343,1.8526640136185266,1.9933274484979564,0.3173078764001649,0.30204211533490194,1.650473249640468,2.025180715051222,-0.16300366701431568,2.5064930869004933,-0.09615352598164383,0.4821074349746622,1.2675738869198223,0.36281679569392605,0.17814470796339205,2.78300653577057,1.3784966610797764,1.4389960408956042,-0.030206765888258928
| 3,069
|
Intrinsic component of mitochondrial membrane
| 29
| 50
| 4.202323
| 0.000026
|
O60830,Q99595,Q96AQ8,Q8N8Q8,Q9Y2R0,Q9H3K2,Q6UXV4,O96008,Q15070,O14925,Q9H4I9,Q96NB2,Q9GZY8,Q6P4A7,P12235,Q9NX63,O43819,Q9UG56,Q8IWA4,Q96ER9,Q9BPX6,P57105,O75880,Q9BUB7,Q5HYI7,Q9HC21,Q13505,Q9Y512,Q5XKP0
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
0,3,514,389,11,397,519,399,143,146,24,413,544,290,553,445,563,69,327,594,343,209,463,469,223,488,104,367,244
|
146,563,0,681,463,757,835,1463,399,553,2415,1295,970,209,913,104,143,934,661,827,223,244,290,519,327,743,1111,389,1580,604,514,594,413,3,343,469,544,397,24,769,770,488,1007,1030,445,69,799,11,865,367
|
1.950506657749701,0.5841039652256301,4.125669255470878,0.43772031258177796,0.7540350803801485,0.36281679569392605,0.2867278246330759,-0.1294642520833557,0.8776079734066499,0.6128502332132403,-0.6212288478544631,-0.030206765888258928,0.17814470796339205,1.5810509907278525,0.22497962854566572,2.351702020702256,1.9719673804988322,0.2094183652836215,0.4673573625937165,0.30204211533490194,1.5105686587244185,1.4027910875879954,1.2300052027613868,0.655647241447091,1.0896121215347725,0.37789124027862775,0.08309274884485632,0.9046357978310428,-0.17986003989876528,0.5406573616707142,0.669827883440752,0.5551835148202413,0.836774272954116,4.125669255470878,1.0505819654024655,0.7540350803801485,0.6271586509706826,0.8911412130144085,3.475941491201594,0.36281679569392605,0.36281679569392605,0.7261314845184232,0.16243171108876198,0.14666752913432865,0.7955852218137351,2.7561169853489744,0.33252539041368356,3.677076391361871,0.2713647192914942,0.9582316246880604
| 3,069
|
Mitochondrial transmembrane transport
| 26
| 52
| 4.165261
| 0.000031
|
O60830,Q99595,Q96AQ8,Q9Y619,O96008,P21796,O14925,Q9H4I9,Q9UJS0,Q8N4Q1,Q96NB2,Q6P4A7,Q3ZCQ8,P23786,P12235,P00846,P12236,O95831,P24539,Q9BQT8,Q96ER9,Q9BPX6,Q8WWC4,O75964,O43772,Q8IYU8
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
0,3,514,131,399,15,146,24,547,412,413,290,541,166,553,42,565,564,448,75,594,343,210,93,116,384
|
146,1096,116,0,1013,1428,1125,1520,93,757,591,1463,564,399,42,1054,908,2162,553,565,15,166,448,1956,928,2865,970,1262,1059,840,913,2147,541,290,384,412,1580,2487,210,514,594,413,3,343,75,24,769,1136,547,1309,865,131
|
1.950506657749701,0.08309274884485632,2.2218852461661323,4.125669255470878,0.14666752913432865,-0.11278048268758513,0.06706796620069248,-0.16300366701431568,2.449071204722446,0.36281679569392605,0.5551835148202413,-0.1294642520833557,0.5841039652256301,0.8776079734066499,3.034827813634531,0.11498437510700303,0.22497962854566572,-0.4756480043806108,0.6128502332132403,0.5841039652256301,3.551536551149184,1.8526640136185266,0.781775583130449,-0.3692094267674327,0.2094183652836215,-1.0049855843887756,0.17814470796339205,-0.013858605375158513,0.11498437510700303,0.2867278246330759,0.22497962854566572,-0.45774800066276633,0.6271586509706826,1.2300052027613868,0.9180919307885846,0.836774272954116,-0.17986003989876528,-0.6583020446262418,1.5693783522525775,0.669827883440752,0.5551835148202413,0.836774272954116,4.125669255470878,1.0505819654024655,2.6836037582923837,3.475941491201594,0.36281679569392605,0.06706796620069248,0.6271586509706826,-0.030206765888258928,0.2713647192914942,2.0462929128969036
| 3,069
|
Inner mitochondrial membrane protein complex
| 29
| 78
| 4.112108
| 0.000039
|
O60830,Q99595,P14406,Q9P0J0,O14925,Q9H4I9,P21912,Q9Y584,Q9Y6M9,P62072,O43676,P00846,Q86Y39,Q9NX63,Q9UDW1,O75306,O14949,Q99623,Q9BPX6,O75964,Q5HYI7,O96000,Q96CU9,Q13505,P00403,Q9Y512,P03915,Q5XKP0,Q8IYU8
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
0,3,1,271,146,24,158,32,161,35,38,42,179,445,57,437,70,333,343,93,223,225,230,104,108,367,242,244,384
|
679,1218,146,70,1945,38,1288,0,1836,437,2312,681,1429,1520,93,590,1947,225,108,42,242,908,910,1951,1167,565,538,1,1198,2098,2132,778,158,668,448,1956,2899,1606,1315,1077,928,2415,969,2865,2797,1434,1059,840,35,104,881,2519,661,541,827,223,244,519,179,384,1580,230,674,3,333,343,24,1136,1030,445,271,57,964,717,865,367,32,161
|
0.43772031258177796,0.002434827265685641,1.950506657749701,2.7380995161851818,-0.3692094267674327,3.143192229979514,-0.030206765888258928,4.125669255470878,-0.3168403575565848,0.7955852218137351,-0.5661333020712928,0.43772031258177796,-0.11278048268758513,-0.16300366701431568,2.449071204722446,0.5551835148202413,-0.3692094267674327,1.4987164375383368,2.3319722280450734,3.034827813634531,1.4269590798007796,0.22497962854566572,0.22497962854566572,-0.3692094267674327,0.0348588523240148,0.5841039652256301,0.6271586509706826,4.125669255470878,0.018673868634717674,-0.439912661259074,-0.45774800066276633,0.3476949375688096,1.8745887034572348,0.45256174173642805,0.781775583130449,-0.3692094267674327,-1.0853969322237222,-0.1967746802526644,-0.04660999391817365,0.09906477879078189,0.2094183652836215,-0.6212288478544631,0.17814470796339205,-1.0049855843887756,-0.9062487336772611,-0.11278048268758513,0.11498437510700303,0.2867278246330759,3.2085671141055583,2.351702020702256,0.255952511861343,-0.6769429135129599,0.4673573625937165,0.6271586509706826,0.30204211533490194,1.5105686587244185,1.4027910875879954,0.655647241447091,1.7862524375899929,0.9180919307885846,-0.17986003989876528,1.474920572686217,0.45256174173642805,4.125669255470878,1.0636280893102765,1.0505819654024655,3.475941491201594,0.06706796620069248,0.14666752913432865,0.7955852218137351,1.2924526686835236,2.8451205119843253,0.19380682512269046,0.4078989792455411,0.2713647192914942,0.9582316246880604,3.248934240656014,1.8745887034572348
| 3,069
|
Mitochondrial transport
| 33
| 85
| 4.101272
| 0.000041
|
O60830,Q99595,Q9NS69,Q9Y5J9,O14737,Q8N8Q8,P45880,Q15070,Q9P0J0,O96008,Q96EK5,O14925,Q8N4H5,Q8N4Q1,Q99797,Q9Y584,P62072,P23786,P00846,Q5JRX3,Q10713,P30536,Q6NUK1,Q9UBX3,P52789,O00165,P55786,Q8WWC4,O60220,O75964,Q9Y512,O43772,P51572
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
0,3,4,258,381,389,8,143,271,399,402,146,25,412,286,32,35,166,42,431,177,53,441,56,188,314,76,210,335,93,367,116,377
|
314,1163,381,146,1096,116,335,0,681,1428,1520,93,757,835,2952,2218,564,399,42,952,1054,908,2315,1490,2162,553,2872,166,448,1956,2137,2762,53,2795,928,2100,8,2865,790,1961,1917,970,377,188,76,1059,840,35,1437,177,143,2579,541,827,431,441,2687,743,1111,25,412,389,604,210,402,2303,1091,3,286,544,1136,1007,4,271,1417,2087,56,864,547,1309,964,1120,367,32,258
|
1.1283203698531714,0.0348588523240148,0.9180919307885846,1.950506657749701,0.08309274884485632,2.2218852461661323,1.0505819654024655,4.125669255470878,0.43772031258177796,-0.11278048268758513,-0.16300366701431568,2.449071204722446,0.36281679569392605,0.2867278246330759,-1.2292802103878024,-0.511643742111834,0.5841039652256301,0.8776079734066499,3.034827813634531,0.19380682512269046,0.11498437510700303,0.22497962854566572,-0.5661333020712928,-0.14620519285903205,-0.4756480043806108,0.6128502332132403,-1.0249681947485962,1.8526640136185266,0.781775583130449,-0.3692094267674327,-0.45774800066276633,-0.8672923859684633,2.915054362320261,-0.9062487336772611,0.2094183652836215,-0.439912661259074,3.7990432016623545,-1.0049855843887756,0.33252539041368356,-0.3692094267674327,-0.3516910545716578,0.17814470796339205,0.931509813270278,1.7301647060416219,2.6376742328100615,0.11498437510700303,0.2867278246330759,3.2085671141055583,-0.11278048268758513,1.7862524375899929,1.9719673804988322,-0.7144356079504978,0.6271586509706826,0.30204211533490194,0.8093547404733235,0.7955852218137351,-0.79027866305354,0.37789124027862775,0.08309274884485632,3.445328693074278,0.836774272954116,0.9046357978310428,0.5406573616707142,1.5693783522525775,0.8776079734066499,-0.5479033919239744,0.09906477879078189,4.125669255470878,1.242561719212632,0.6271586509706826,0.06706796620069248,0.16243171108876198,4.125669255470878,1.2924526686835236,-0.09615352598164383,-0.42214155708180023,2.8451205119843253,0.2713647192914942,0.6271586509706826,-0.030206765888258928,0.19380682512269046,0.08309274884485632,0.9582316246880604,3.248934240656014,1.366301653124708
| 3,069
|
Subsets and Splits
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