term
stringlengths
2
121
overlap
int64
6
281
setsize
int64
7
499
score
float64
1.96
10.6
pval
float64
0
0.05
edge
stringlengths
41
1.97k
type
stringclasses
5 values
subtype
stringclasses
24 values
subtype_key
stringclasses
24 values
edge_idxs
stringlengths
11
1.17k
ann_idxs
stringlengths
19
2.31k
ann_vals
stringlengths
124
9.94k
sig_size
int64
2.2k
3.73k
Mitochondrial protein import
12
39
3.386773
0.000707
Q9NS69,Q9Y584,O60830,Q99595,Q96B49,P21796,P06576,Q5JRX3,Q9NX63,O75431,O60220,Q8N4H5
Processes and pathways
Reactome Pathways
msigdb_reactome
0,73,5,8,367,77,109,317,253,404,436,94
2169,976,436,5,3312,404,3210,2025,1842,2591,109,767,2378,2335,2632,77,1316,2636,1370,521,749,1855,2990,317,94,3351,367,8,2930,602,0,253,2013,1676,1403,73,1555,825,2165
-0.2425328384980788,0.43727634598424736,1.0084511164761645,4.4394304513124805,-1.1657815930185491,1.074981518864855,-1.0280906020982006,-0.16743166552350902,-0.06818453902065648,-0.4971701187929715,2.0482786735043907,0.6234430164808086,-0.3690078123018647,-0.34357988327025807,-0.5230108310595,2.3090642821729386,0.22373...
3,643
RNA recognition motif domain [IPR000504]
52
121
3.381115
0.000722
Q9NTZ6,P07910,P23246,P08621,Q13151,Q8WUA2,P19338,Q9Y6M1,Q07955,P55795,P98175,P05455,P22626,Q9UHX1,P11940,P62995,O60506,P35637,P38159,Q15056,P33240,Q86U42,P31942,P52272,Q9UN86,Q01844,P08579,P23588,Q8IXT5,Q15233,Q14011,O15042,Q8WXF1,Q8N684,O14979,Q5T8P6,O43390,P78332,O43719,Q9UKA9,Q92804,Q15427,P31943,Q9NZI8,P98179,P0901...
Sequence
InterPro Domain
interpro_domain
527,1007,132,889,639,668,1009,412,663,662,24,152,658,548,656,788,403,284,161,790,414,432,426,809,969,188,437,311,961,70,207,827,78,473,826,468,457,986,977,491,228,225,982,761,234,610,745,615,1037,650,774,129
1921,826,827,3184,457,977,403,2074,2943,2176,2502,152,1007,437,889,610,1883,656,3137,1685,1009,658,132,311,1799,2422,2856,426,982,414,284,161,1934,1320,1369,2426,809,1719,745,662,1766,788,986,1376,24,234,2602,1277,188,2348,663,1724,1447,2306,639,1327,3047,2478,1411,2713,774,207,1281,2752,2089,3560,1987,790,70,615,2790,...
-0.11768281781113353,0.5540203428545035,0.5540203428545035,-1.0008034862861284,0.9638691945115666,0.43727634598424736,1.074981518864855,-0.1924012006648247,-0.7588269213757284,-0.2425328384980788,-0.445698559329321,1.8229962075770718,0.41376856372481113,1.0084511164761645,0.507480352534478,0.7836669490667206,-0.0929025...
3,643
Cortical cytoskeleton
19
47
3.379889
0.000725
Q05682,P46940,P46939,O43707,P67936,Q14980,P35240,O75955,Q8IUD2,P35579,Q01082,P35241,P12814,P11166,P05771,Q14254,Q13813,O15020,P15311
Localization
GO Cellular component
msigdb_gocc
381,634,518,260,15,419,157,530,43,298,206,67,332,203,340,483,105,605,124
605,1218,260,2817,530,340,203,1639,332,124,2127,2222,2224,157,67,298,518,634,2554,2980,3530,2136,3236,15,2389,206,1569,381,2920,638,105,2788,1771,483,3104,419,2395,1809,2090,1653,2720,2046,43,3475,1868,2621,2166
0.7836669490667206,0.2715793302199121,1.401701779928311,-0.6532860190318247,0.8741475129403571,1.206835559918556,1.6143043553854377,0.054488318052800216,1.2286577968396193,1.9668614518667913,-0.21743476674892134,-0.26769589647874387,-0.26769589647874387,1.8022971674617145,2.4078652087559544,1.3155174609171851,0.8966483...
3,643
Cation transport
45
161
3.375171
0.000738
Q9UM00,Q9Y4W6,Q15043,P62258,O76024,P46939,O43707,Q9UDW1,Q9UJZ1,Q93034,P05067,O00429,P27105,O75964,Q9NW15,O95202,Q99808,O60610,O15173,Q13423,Q70HW3,O43772,O95747,O75323,P36542,P50570,P18859,P21796,Q9HD20,P24539,P05771,Q9UNH7,Q8N4V1,O75844,Q9Y6M7,P13073,P56385,Q99623,P06576,P0DP25,Q9H0U3,P33176,Q6P4Q7,P30825,P07355
Processes and pathways
GO Biological process
msigdb_gobp
528,529,134,136,633,518,260,18,549,289,156,160,283,35,692,413,559,675,172,53,441,61,568,566,572,322,75,77,85,219,340,629,226,351,631,104,482,236,109,110,242,238,245,371,494
3006,1256,160,3114,1146,856,948,172,260,61,1183,1039,675,785,3036,566,3210,351,1311,35,633,413,568,1149,1044,2218,1263,2413,156,2670,3430,340,109,494,3094,1188,888,1118,767,110,1970,1639,2026,2335,104,1266,1315,2028,744,2298,2126,2915,75,1798,1046,1074,2264,2706,3335,77,2671,219,1268,1316,283,3068,2339,3469,2466,3139,3...
-0.8120509037528868,0.247687286863095,1.781560842290383,-0.9194313337399534,0.3191957867311709,0.5307763897453316,0.46073067332952794,1.7191262091211201,1.401701779928311,2.4863261827117857,0.2954153714992455,0.39020697451391223,0.7152972491503666,0.6003533278278015,-0.838778477489919,0.8290032464607571,-1.028090602098...
3,643
Vacuolar membrane
38
134
3.364053
0.000768
Q8NCG7,Q9H0B6,Q8N511,Q14849,Q15043,Q9BTU6,Q8WTV0,O75955,Q93050,P42785,P27105,P86790,Q07065,Q8NF37,Q9BXS5,Q14108,O15118,Q9Y5K8,Q8NB49,O75503,Q8IV08,P42892,P07602,Q9Y487,Q8IY95,P31946,O15400,P10253,P42345,O60271,Q96QK1,Q9H0U3,P33176,P04844,Q16625,O95721,P08238,P07355
Localization
GO Cellular component
msigdb_gocc
523,256,4,6,134,399,150,530,30,32,283,534,36,433,435,47,50,180,578,181,183,59,76,79,336,213,586,231,480,477,241,242,238,370,122,119,495,494
2067,1488,50,1361,586,3391,715,477,716,2333,1491,181,530,1843,119,858,3640,859,370,494,76,1188,888,1118,495,3037,1795,231,2944,1314,743,1190,2379,1191,2463,2264,2706,1930,283,213,238,2128,2597,1318,480,32,59,1507,3407,2783,3014,679,1079,1718,1605,2892,2710,771,1767,1324,3380,2831,1124,3072,534,1081,2919,36,2984,2234,72...
-0.1924012006648247,0.1273735787791028,2.6802893561721626,0.19973366863516875,0.8063592485767881,-1.3056344536808002,0.6694704024024033,0.9415089211120462,0.6694704024024033,-0.34357988327025807,0.1273735787791028,1.6773130953634898,0.8741475129403571,-0.06818453902065648,1.9872689975161881,0.5307763897453316,-6.296141...
3,643
Vacuole organization
22
56
3.363881
0.000769
Q8N511,O95352,Q86VS8,Q96ED9,P50897,O14773,Q9H269,Q9UNZ2,Q14108,Q6IAA8,O75503,P54802,Q12768,Q8WVM8,P10253,Q96AX1,P42345,P04062,Q96QK1,P11117,P16615,P07355
Processes and pathways
GO Biological process
msigdb_gobp
4,887,149,424,31,162,821,174,47,813,181,216,342,870,231,757,480,859,241,743,744,494
2067,162,2073,181,1441,887,859,494,3066,231,743,744,1762,480,1566,31,3014,216,2710,1767,2033,342,47,897,1729,1019,2717,813,1459,1199,1527,149,2242,4,1820,870,757,424,1469,3157,241,1473,1136,821,1663,1428,2063,1479,2113,174,1675,1400,2163,1354,2370,3503
-0.1924012006648247,1.7607870381690778,-0.1924012006648247,1.6773130953634898,0.1515514229907377,0.507480352534478,0.5307763897453316,0.9191020703510948,-0.86558396744226,1.5085051089288772,0.6464819347119302,0.6464819347119302,-0.01893323196983534,0.9415089211120462,0.10313738534059588,3.0406193462815296,-0.8120509037...
3,643
Cis golgi network
7
15
3.354507
0.000795
P24390,O95249,Q14789,P30533,Q8TBA6,Q86VS8,O00461
Localization
GO Cellular component
msigdb_gocc
1,224,323,39,178,149,87
87,224,1,39,427,1695,1570,323,1019,149,178,870,1821,1701,970
2.2294317463628888,1.5297444135769949,5.128435927033103,2.909075983363271,1.030673311900084,0.03007461598016483,0.10313738534059588,1.2504368617067947,0.41376856372481113,1.843658154878481,1.698238787966205,0.5307763897453316,-0.04352823551645443,0.03007461598016483,0.46073067332952794
3,643
Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen
13
35
3.350742
0.000806
P13674,O95864,P16435,Q32P28,Q15800,O60568,Q9BU89,P30519,Q6UW02,Q16850,O15460,O15121,P09601
Functions
GO Molecular function
msigdb_gomf
569,128,570,266,40,321,475,13,14,240,456,116,63
2500,1145,116,456,920,321,3007,1714,1148,128,1593,63,569,570,1367,13,2227,929,2712,641,40,240,266,1232,1416,1814,14,2900,1907,3051,475,1830,2805,2410,2937
-0.445698559329321,0.3191957867311709,2.007640931103598,0.9638691945115666,0.48413189400814893,1.2504368617067947,-0.8120509037528868,0.005600908079439391,0.3191957867311709,1.9464181144490575,0.07884243567085535,2.4863261827117857,0.8290032464607571,0.8290032464607571,0.19973366863516875,3.749679860737421,-0.267695896...
3,643
Ventricular hypertrophy
13
38
3.343462
0.000827
Q15233,P40939,P03886,O75844,P10253,P11047,P02545,Q07021,Q8WZ42,P23786,Q7L0Y3,O75431,O43772
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
70,573,90,351,231,218,42,335,179,461,541,404,61
1114,61,404,351,1364,979,1149,42,90,2880,231,218,2335,1844,2028,2464,461,3170,571,2128,1763,573,2386,1803,1445,335,1280,1379,70,1941,541,1059,2687,2992,179,1099,1244,2322
0.34292094779173377,2.4863261827117857,1.074981518864855,1.184969903794314,0.19973366863516875,0.43727634598424736,0.3191957867311709,2.871236707602699,2.1492621159839103,-0.7059069408091564,1.5085051089288772,1.5509437761405507,-0.34357988327025807,-0.06818453902065648,-0.16743166552350902,-0.4200666292018141,0.963869...
3,643
Parkinsons disease
15
59
3.340593
0.000836
O43676,P03886,P45880,P13073,P14406,P18859,P21796,P06576,P22695,Q9UDW1,O14949,Q16718,P24539,P14927,Q9Y6M9
Processes and pathways
KEGG Pathways
msigdb_kegg
3,90,352,104,10,75,77,109,81,18,115,316,219,92,258
359,3114,1146,2289,115,3,2973,3036,829,2588,1004,1591,1311,1495,3577,2334,2077,1149,90,2670,109,767,513,1970,2335,2632,104,10,2028,92,2705,2548,75,3569,1074,77,2464,1930,81,219,1316,3394,3170,1688,572,1598,352,2469,3408,1976,1080,1511,1608,316,775,3498,18,2623,258
1.1630605789708375,-0.9194313337399534,0.3191957867311709,-0.3182189232285267,2.007640931103598,4.573298093913296,-0.7854005981288927,-0.838778477489919,0.5540203428545035,-0.4971701187929715,0.41376856372481113,0.07884243567085535,0.22373886117967634,0.1273735787791028,-1.8888027743308256,-0.34357988327025807,-0.19240...
3,643
Ion homeostasis
42
115
3.330043
0.000868
Q92544,Q16891,Q8N511,Q9UM00,Q9Y4W6,Q15043,P62258,O76024,P08133,P30519,P51572,Q9UJZ1,P28482,P05067,Q93050,P50897,O75027,O95202,Q96A33,O60610,P27361,Q14344,P51790,O75503,P09601,P04920,P09429,Q9Y487,Q9HD20,Q96TC7,O60826,P05771,P12277,Q9Y6M7,Q96AX1,O14745,Q15904,P06576,P0DP25,Q9Y6N1,Q6P4Q7,P16615
Processes and pathways
GO Biological process
msigdb_gobp
524,255,4,528,529,134,136,633,888,13,276,549,659,156,30,31,785,413,301,675,297,812,679,181,63,698,831,79,85,876,459,340,95,631,757,856,366,109,110,764,245,744
2067,1488,856,949,2454,675,459,785,181,1364,3555,633,3495,413,3300,1044,3483,2218,698,1263,2413,156,340,109,3066,1188,888,831,63,1561,1594,110,95,2778,1266,1150,744,2298,2126,1798,1046,2080,2671,297,3068,3536,2339,659,13,2466,3139,2597,2185,1801,2981,31,3014,276,679,2828,2269,1052,1324,136,3016,2917,1981,1695,2749,1723...
-0.1924012006648247,0.1273735787791028,0.5307763897453316,0.46073067332952794,-0.4200666292018141,0.7152972491503666,0.9638691945115666,0.6003533278278015,1.6773130953634898,0.19973366863516875,-1.7987265678678774,0.7609260502934108,-1.5631438311339427,1.0528500237537732,-1.1380735345018604,0.39020697451391223,-1.53414...
3,643
Regulation of cellular ph
13
23
3.315775
0.000914
Q92544,Q8N511,P04920,Q9Y6M7,Q15904,P27361,P06576,Q9Y487,P51790,O75503,P28482,Q93050,P50897
Processes and pathways
GO Biological process
msigdb_gobp
524,4,698,631,366,297,109,79,679,181,659,30,31
181,698,109,1594,297,659,31,3014,679,1324,1723,897,366,4,524,30,757,1479,1251,1550,79,3183,631
1.6773130953634898,0.6924087361167105,2.0482786735043907,0.07884243567085535,1.3155174609171851,0.7381362515768051,3.0406193462815296,-0.8120509037528868,0.7152972491503666,0.22373886117967634,0.005600908079439391,0.507480352534478,1.1630605789708375,4.556634981497133,0.8966483619769324,3.096576582716819,0.646481934711...
3,643
Regulation of ph
13
23
3.315775
0.000914
Q92544,Q8N511,P04920,Q9Y6M7,Q15904,P27361,P06576,Q9Y487,P51790,O75503,P28482,Q93050,P50897
Processes and pathways
GO Biological process
msigdb_gobp
524,4,698,631,366,297,109,79,679,181,659,30,31
181,698,109,1594,297,659,31,3014,679,1324,1723,897,366,4,524,30,757,1479,1251,1550,79,3183,631
1.6773130953634898,0.6924087361167105,2.0482786735043907,0.07884243567085535,1.3155174609171851,0.7381362515768051,3.0406193462815296,-0.8120509037528868,0.7152972491503666,0.22373886117967634,0.005600908079439391,0.507480352534478,1.1630605789708375,4.556634981497133,0.8966483619769324,3.096576582716819,0.646481934711...
3,643
Endoplasmic reticulum organization
20
49
3.308692
0.000937
Q15363,Q9P0I2,A0MZ66,A0FGR8,Q9NQC3,O00429,P46379,Q15006,Q96A33,O43681,P49069,P49257,Q9P2W9,Q8N5M9,P57088,Q8N4V1,Q15629,O95197,Q15041,Q9NPA0
Processes and pathways
GO Biological process
msigdb_gobp
137,280,387,654,425,160,165,537,301,673,678,194,210,599,593,226,106,251,125,781
654,387,160,1678,2170,2702,673,1841,1792,251,3300,165,678,194,2267,593,3279,2473,1721,1448,1610,537,125,1729,137,106,2518,1231,3471,226,599,1238,3053,1336,301,2320,1473,780,1428,2104,908,2105,781,425,1670,280,2875,210,1791
0.7381362515768051,1.097068061484193,1.781560842290383,0.03007461598016483,-0.2425328384980788,-0.5749048809587229,0.7152972491503666,-0.06818453902065648,-0.04352823551645443,1.4445453596918503,-1.1380735345018604,1.7607870381690778,0.7152972491503666,1.6353460842060628,-0.292924427202373,0.8063592485767881,-1.1104511...
3,643
ATP synthase
10
21
3.307338
0.000942
O75964,P56385,P18859,Q15904,P06576,Q9Y487,Q9Y5K8,Q6IN85,P24539,Q93050
Functions
Panther Protein class
panther_protein_class
35,482,75,366,109,79,180,540,219,30
1311,35,109,75,2264,2706,219,1316,572,2597,2469,2429,482,1324,366,540,30,1950,1550,79,180
0.22373886117967634,2.9844124544918555,2.0482786735043907,2.348682347368294,-0.292924427202373,-0.5749048809587229,1.5509437761405507,0.22373886117967634,0.8290032464607571,-0.4971701187929715,-0.4200666292018141,-0.394503221669089,0.9415089211120462,0.22373886117967634,1.1630605789708375,0.8741475129403571,3.096576582...
3,643
Protein localization to organelle
77
368
3.302952
0.000957
Q9NS69,P24390,Q10713,O60830,Q99595,P07900,Q9P0J0,Q15006,Q9H900,Q9BVL2,P02545,Q14108,O14737,P83436,Q9Y584,P35241,P12270,Q8N4H5,P26038,Q15629,P0DP25,P55786,P67809,P15311,Q9UPT5,P62258,Q96A65,Q9UH99,Q86VS8,P05455,Q9H4M9,Q8WXW3,P35240,O00429,O14773,P46379,Q15276,Q9UNZ2,Q9Y5K8,Q9UPN4,Q15070,P49257,O75381,Q8NCM8,Q8N4V1,Q9962...
Processes and pathways
GO Biological process
msigdb_gobp
0,1,521,5,8,512,34,537,563,560,42,47,60,575,73,67,91,94,96,106,110,120,121,124,135,136,139,140,149,152,154,159,157,160,162,165,166,174,180,191,196,194,202,217,226,236,241,239,276,280,282,301,307,317,313,329,323,348,345,350,343,360,362,382,380,394,419,425,427,436,474,470,488,487,493,497,495
971,1114,2067,714,160,1557,1960,1488,60,162,2625,2777,2169,3033,1678,1753,2170,884,739,2022,916,2023,360,2702,3391,976,2372,673,3360,1841,2290,2940,436,1755,675,1756,5,857,282,1185,1964,202,3210,2501,1006,1842,1068,2545,1441,886,1365,2590,2375,2120,380,2591,42,1044,2628,152,1683,493,512,495,2261,3598,1561,110,2378,1190...
0.43727634598424736,0.34292094779173377,-0.1924012006648247,0.6694704024024033,1.781560842290383,0.10313738534059588,-0.1425256923482076,0.1273735787791028,2.4863261827117857,1.7607870381690778,-0.5230108310595,-0.62708619656327,-0.2425328384980788,-0.838778477489919,0.03007461598016483,-0.01893323196983534,-0.24253283...
3,643
Mitochondrial protein containing complex
39
167
3.300513
0.000965
Q9NS69,Q16891,O43676,O60830,Q9Y4W6,P09669,Q99595,P14406,Q567V2,Q9UDW1,Q7L0Y3,O75431,Q9P0J0,O75964,Q16718,O60220,Q9Y584,P40939,P36542,P18859,Q9HAV7,P21796,P22695,Q92552,P03886,P24539,P14927,P49406,Q8N4H5,P56385,P13073,P52815,Q99623,P06576,O00217,O14949,Q9NX63,Q7Z7H8,Q9Y6M9
Localization
GO Cellular component
msigdb_gocc
0,255,3,5,529,513,8,10,392,18,541,404,34,35,316,436,73,573,572,75,602,77,81,346,90,219,92,462,94,482,104,233,236,109,359,115,253,384,258
359,1357,3114,1146,974,2169,115,2371,3,2973,588,436,2373,5,3036,829,2588,404,1004,1591,1311,35,1559,1842,1495,3577,2334,2077,2591,1149,90,2670,109,2296,767,2415,2219,513,3095,1970,2457,2592,2335,2632,807,104,10,2028,92,2705,2548,75,3569,1074,77,2464,3599,81,219,1316,3394,3469,3170,1688,2825,572,2636,573,2469,462,3408,2...
1.1630605789708375,0.19973366863516875,-0.9194313337399534,0.3191957867311709,0.43727634598424736,-0.2425328384980788,2.007640931103598,-0.3690078123018647,4.573298093913296,-0.7854005981288927,0.8063592485767881,1.0084511164761645,-0.3690078123018647,4.4394304513124805,-0.838778477489919,0.5540203428545035,-0.49717011...
3,643
Calcium ion binding
24
86
3.284532
0.001022
Q9UPN3,O43707,P67936,Q96D71,P80303,Q9H4M9,O43852,O95202,Q9BRK5,Q96A33,Q03001,Q15293,Q14257,Q8WZ42,Q9UM22,P55327,Q99584,P12814,Q02818,P41208,Q13813,Q9NWM8,P0DP25,P14314
Functions
GO Molecular function
msigdb_gomf
402,260,15,278,22,154,38,413,41,301,431,45,48,179,55,65,66,332,83,93,105,107,110,114
654,1751,2666,673,260,38,2175,1714,2025,1494,413,3640,1069,2547,1968,494,3094,888,1927,110,2027,332,1266,3628,114,1150,744,2127,2222,1798,699,2979,3536,1153,2301,3139,2550,93,892,3187,634,3264,65,2430,864,15,22,83,431,1852,2712,105,3120,48,2189,2350,3104,45,3147,1941,1735,2689,3127,1167,433,1578,179,301,1908,3201,278,6...
0.7381362515768051,-0.01893323196983534,-0.5489222320312916,0.7152972491503666,1.401701779928311,2.909075983363271,-0.2425328384980788,0.005600908079439391,-0.16743166552350902,0.1273735787791028,1.0528500237537732,-6.296141961009042,0.3665912224666737,-0.47139954319819993,-0.1425256923482076,0.9191020703510948,-0.8924...
3,643
Electron transport chain oxphos system in mitochondria
15
55
3.281749
0.001032
O75964,O43676,P03886,P13073,P14406,P18859,P06576,P22695,Q9UDW1,O14949,Q9UII2,Q16718,P24539,P14927,Q9Y6M9
Processes and pathways
WikiPathways
msigdb_wp
35,3,90,104,10,75,109,81,18,115,350,316,219,92,258
359,3114,1146,115,3,2973,3036,829,2588,1004,1591,1364,1311,35,1495,3577,2334,2077,1149,90,2670,109,513,1970,2335,2632,104,10,2028,92,2705,2548,75,3569,1074,2464,81,219,1316,3394,3170,1688,572,2469,3408,1976,2429,482,316,775,3606,18,350,258,764
1.1630605789708375,-0.9194313337399534,0.3191957867311709,2.007640931103598,4.573298093913296,-0.7854005981288927,-0.838778477489919,0.5540203428545035,-0.4971701187929715,0.41376856372481113,0.07884243567085535,0.19973366863516875,0.22373886117967634,2.9844124544918555,0.1273735787791028,-1.8888027743308256,-0.3435798...
3,643
Monovalent inorganic cation homeostasis
13
31
3.280774
0.001035
Q92544,Q8N511,P04920,Q9Y6M7,Q15904,P27361,P06576,Q9Y487,P51790,O75503,P28482,Q93050,P50897
Processes and pathways
GO Biological process
msigdb_gobp
524,4,698,631,366,297,109,79,679,181,659,30,31
181,2218,698,1263,2413,109,1594,297,659,31,3014,679,2269,1052,1324,1723,897,366,4,524,30,757,1033,1426,1479,1251,1550,79,1875,3183,631
1.6773130953634898,-0.26769589647874387,0.6924087361167105,0.247687286863095,-0.394503221669089,2.0482786735043907,0.07884243567085535,1.3155174609171851,0.7381362515768051,3.0406193462815296,-0.8120509037528868,0.7152972491503666,-0.292924427202373,0.39020697451391223,0.22373886117967634,0.005600908079439391,0.5074803...
3,643
Protein transport
90
290
3.279547
0.00104
Q9NS69,P24390,O60830,Q99595,P49321,Q8WU76,Q9BVL2,Q8IUD2,O14653,Q9P2D3,P83436,Q99584,Q9Y584,Q8N5M9,Q9HD20,P12270,P41208,Q8N4H5,Q9UNH7,Q8IWJ2,Q15629,Q9Y3B3,O95721,Q9NV70,Q9UPT5,Q15363,Q96A65,Q86VS8,Q9H4M9,Q15276,Q86VN1,Q9Y5L0,Q9UP83,P49257,Q9P2W9,Q6NUQ1,O75381,O60749,Q10567,O43747,O60784,O00410,O95249,Q96AX1,Q96T51,Q1503...
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
0,1,5,8,519,543,560,43,550,583,575,66,73,599,85,91,93,94,629,619,106,653,119,651,135,137,139,149,154,166,685,713,711,194,210,731,202,201,726,715,716,714,224,757,760,752,241,239,746,250,749,770,260,771,276,277,821,291,294,825,803,849,330,338,345,339,872,342,343,870,868,367,858,375,903,899,887,897,892,404,424,435,427,436...
971,1750,1589,3006,2775,2067,714,947,1557,2851,1488,550,2777,1490,2169,1753,2170,803,339,916,1840,2023,976,260,715,3209,2290,436,2703,1755,1756,201,330,716,459,5,291,1491,202,2073,404,1363,2501,1043,1843,1792,250,2668,224,887,1365,1966,2178,119,858,2591,1594,91,3346,1499,1929,1762,950,1,2302,1502,1597,3316,2782,93,892,...
0.43727634598424736,-0.01893323196983534,0.07884243567085535,-0.8120509037528868,-0.62708619656327,-0.1924012006648247,0.6694704024024033,0.46073067332952794,0.10313738534059588,-0.6795594013194657,0.1273735787791028,0.8515992373556479,-0.62708619656327,0.1273735787791028,-0.2425328384980788,-0.01893323196983534,-0.242...
3,643
Organelle biogenesis and maintenance
30
107
3.272621
0.001066
Q92845,Q10713,Q16891,Q9UPT5,P62258,Q96A65,P07900,Q00059,O75935,O95684,O75431,O75964,Q04837,Q9NQ48,Q14203,Q13561,Q9UPN4,O43805,P18859,O94927,Q15019,Q8NCM8,P24539,P41208,P56385,P06576,P06493,P61981,Q96CS2,Q9NX63
Processes and pathways
Reactome Pathways
msigdb_reactome
525,521,255,135,136,139,512,145,273,274,404,35,168,307,189,576,191,447,75,331,465,217,219,93,482,109,493,500,252,253
971,1357,947,447,2292,404,273,1311,35,331,676,274,1638,3483,2547,493,109,1758,512,2124,1760,2298,2126,1971,3346,75,832,219,1316,952,3316,572,2636,93,1599,2469,2887,2948,1444,1642,1889,3379,1849,2084,1322,2429,482,3071,926,500,136,3236,2087,681,145,168,2515,521,1648,749,576,2037,1196,189,1806,465,1282,1899,1809,729,255,...
0.43727634598424736,0.19973366863516875,0.46073067332952794,0.9861831680424349,-0.3182189232285267,1.074981518864855,1.3802181900709822,0.22373886117967634,2.9844124544918555,1.2286577968396193,0.7152972491503666,1.3802181900709822,0.054488318052800216,-1.5341498793287338,-0.47139954319819993,0.9191020703510948,2.04827...
3,643
Steroid binding
8
23
3.240886
0.001192
P45880,Q14849,O15173,P21796,Q14108,Q9BZF3,O15118,O00264
Functions
GO Molecular function
msigdb_gomf
352,6,172,77,47,49,50,112
112,50,172,804,1117,859,1263,888,77,2300,2506,2466,1224,555,352,429,2711,47,6,1621,2208,2103,49
2.027977430849258,2.6802893561721626,1.7191262091211201,0.5772125455062541,0.34292094779173377,0.5307763897453316,0.247687286863095,0.507480352534478,2.3090642821729386,-0.3182189232285267,-0.445698559329321,-0.4200666292018141,0.2715793302199121,0.8515992373556479,1.184969903794314,1.030673311900084,-0.574904880958722...
3,643
Signaling by rho gtpases miro gtpases and rhobtb3
106
284
3.225032
0.00126
P30519,P67936,P07900,P08670,Q14739,Q9NYL9,O75955,Q07065,Q9H900,O43663,P20700,O75323,Q86UP2,P12277,Q9Y6M7,Q13813,O75962,Q14738,O75976,P46940,P62258,Q13464,Q9Y6G9,Q5JTV8,P28482,O14974,P35240,P38159,Q9BZH6,Q9UQB8,O60610,O15173,Q9UNZ2,O43237,P78371,O60879,P59998,P49257,Q01082,Q86XL3,Q16539,P31946,P35580,Q14185,P30154,P6299...
Processes and pathways
Reactome Pathways
msigdb_reactome
13,15,512,19,23,546,530,36,563,551,57,566,71,95,631,105,118,614,127,634,136,640,671,666,659,655,157,161,688,695,675,172,174,672,681,186,701,194,206,733,729,213,214,728,719,724,758,238,748,749,256,776,770,276,280,277,287,792,789,788,283,282,298,814,297,296,813,812,811,316,844,842,838,332,335,347,836,833,875,340,877,870,...
2542,2115,3006,655,1753,1633,3416,172,1840,672,2023,1924,551,2740,3360,920,2173,675,1041,186,282,2024,566,1591,530,118,127,1441,413,3300,1044,2547,3430,340,296,3585,512,1007,495,19,2592,95,332,2778,2821,2460,3115,2298,57,3335,3454,283,2338,297,1048,659,2549,952,719,3039,13,213,361,238,1270,3395,497,1501,157,298,214,282...
-0.47139954319819993,-0.21743476674892134,-0.8120509037528868,0.7381362515768051,-0.01893323196983534,0.054488318052800216,-1.3622032056549125,1.7191262091211201,-0.06818453902065648,0.7152972491503666,-0.16743166552350902,-0.11768281781113353,0.8515992373556479,-0.6009593444413444,-1.249427613926466,0.4841318940081489...
3,643
Transport of small molecules
52
168
3.216034
0.0013
Q10713,Q9UBV2,Q9UEY8,Q9Y4W6,Q15043,P30519,O15439,P08183,Q9UJZ1,Q8WTV0,P35612,O00231,Q93050,P51665,P27105,Q9C0H2,Q9NW15,Q13616,O95202,Q99808,Q8TB61,P61916,O15118,Q9Y5K8,P51790,Q15008,Q8NB49,Q70HW3,P40855,P09601,P35613,O43242,P48556,Q96TA2,P21796,Q9Y487,P11166,Q13546,Q9UBX3,Q9HD20,P28070,P62191,Q8N4V1,P45880,Q9Y6M7,P5398...
Processes and pathways
Reactome Pathways
msigdb_reactome
521,270,400,529,134,13,259,275,549,150,660,271,30,661,283,689,692,300,413,559,173,429,50,180,679,577,578,441,313,63,64,309,700,208,77,79,203,595,86,85,589,221,226,352,631,481,366,236,604,242,371,496
271,2586,604,1256,1438,1961,50,259,309,785,3210,804,3480,3555,1117,1843,413,858,3640,1044,698,1263,2413,2670,2414,1593,275,1118,1795,63,1595,203,2335,2632,1928,744,2298,2126,496,1046,923,2594,2264,2706,2080,77,2671,2507,1010,2183,3097,283,2382,589,1687,2823,1048,13,3139,371,2825,1224,1225,660,64,3099,2596,2128,3635,259...
1.3802181900709822,-0.4971701187929715,0.7836669490667206,0.247687286863095,0.1515514229907377,-0.1425256923482076,2.6802893561721626,1.401701779928311,1.2721729993532975,0.6003533278278015,-1.0280906020982006,0.5772125455062541,-1.5341498793287338,-1.7987265678678774,0.34292094779173377,-0.06818453902065648,1.05285002...
3,643
Intrinsic component of endoplasmic reticulum membrane
28
59
3.214915
0.001305
Q9C0E8,Q9UM00,O76024,P51572,Q8TCT9,Q9P0I2,Q6Y1H2,A0FGR8,Q9NQC3,Q15006,Q96A33,Q8TB61,Q5H8A4,P49069,Q8NBI6,Q86UP2,Q86XL3,Q9P2E9,P57088,O95470,Q9Y282,Q8N4V1,O75844,Q9UBM7,Q15629,O43292,Q15041,Q9NPA0
Localization
GO Cellular component
msigdb_gocc
780,528,633,276,793,280,408,654,425,537,301,173,176,678,325,71,733,338,593,718,99,226,351,369,106,360,125,781
654,1145,1752,1880,360,2702,351,633,718,1682,2416,3536,1153,1443,678,276,593,2473,1610,3076,537,125,106,176,2518,3586,408,71,733,902,226,1238,325,173,793,1240,2052,815,301,1340,2153,2320,1175,1473,780,3331,1625,3027,781,425,1036,1433,280,338,369,528,99,2215,3231
0.7381362515768051,0.3191957867311709,-0.01893323196983534,-0.09290258413901609,1.1630605789708375,-0.5749048809587229,1.184969903794314,0.7609260502934108,0.6694704024024033,0.03007461598016483,-0.394503221669089,-1.7096113970661815,0.3191957867311709,0.1515514229907377,0.7152972491503666,1.3802181900709822,0.80635924...
3,643
Vesicle membrane
79
279
3.213565
0.001311
P24390,Q8N511,Q14849,P30519,Q93050,P42785,Q07065,Q14108,Q9BZF3,O15118,O14653,Q8NB49,P42892,P35613,P07602,Q9Y487,Q15075,Q13546,O00461,O15400,Q9UNH7,P0DP25,O00264,O15121,Q9Y3B3,O95721,Q15043,P46940,Q15363,O76024,Q12965,Q9UH99,Q9Y6G9,Q9H223,Q8WTV0,Q9H4M9,O00429,Q15276,Q86VN1,O60610,Q9Y5K8,P51790,Q8IV08,P20073,P49257,O0029...
Localization
GO Cellular component
msigdb_gocc
1,4,6,13,30,32,36,47,49,50,550,578,59,64,76,79,80,595,87,586,629,110,112,116,653,119,134,634,137,633,638,140,671,669,150,154,160,166,685,675,180,679,183,699,194,696,201,726,715,716,724,226,231,757,760,241,242,259,283,291,292,329,322,330,339,366,378,393,406,433,435,427,439,453,446,474,472,483,494
2542,1589,3006,2067,112,696,160,87,2851,1488,550,1490,1752,2170,50,116,803,339,1361,586,259,1840,1880,3614,3391,715,446,1219,2118,2703,675,1041,201,330,716,291,2333,921,1491,2175,2073,1363,1714,633,1843,1792,1966,2178,119,858,3260,3640,1044,1069,1682,3430,494,76,1188,888,1795,2881,1927,110,231,2416,1314,1190,2379,2593,...
-0.47139954319819993,0.07884243567085535,-0.8120509037528868,-0.1924012006648247,2.027977430849258,0.6924087361167105,1.781560842290383,2.2294317463628888,-0.6795594013194657,0.1273735787791028,0.8515992373556479,0.1273735787791028,-0.01893323196983534,-0.2425328384980788,2.6802893561721626,2.007640931103598,0.57721254...
3,643
Lysosomal lumen
20
34
3.202998
0.00136
P17900,P07900,Q9BWS9,Q13510,P50897,O14773,Q14108,O43681,P61916,P15586,P38435,Q9UM22,Q8IV08,P07602,P54802,Q8NHP8,P10253,P04066,Q9UMR5,P11117
Localization
GO Cellular component
msigdb_gocc
515,512,796,158,31,162,47,673,429,305,555,55,183,76,216,227,231,609,108,743
1877,1558,162,673,859,609,2880,2121,76,3066,512,806,231,2944,743,1190,1191,305,1442,515,555,3635,31,216,429,158,47,183,1819,227,796,1141,55,108
-0.09290258413901609,0.10313738534059588,1.7607870381690778,0.7152972491503666,0.5307763897453316,0.7836669490667206,-0.7059069408091564,-0.21743476674892134,2.3090642821729386,-0.86558396744226,0.8966483619769324,0.5772125455062541,1.5085051089288772,-0.7588269213757284,0.6464819347119302,0.2954153714992455,0.29541537...
3,643
Cellular monovalent inorganic cation homeostasis
13
28
3.193785
0.001404
Q92544,Q8N511,P04920,Q9Y6M7,Q15904,P27361,P06576,Q9Y487,P51790,O75503,P28482,Q93050,P50897
Processes and pathways
GO Biological process
msigdb_gobp
524,4,698,631,366,297,109,79,679,181,659,30,31
181,698,1263,2413,109,1594,297,659,31,3014,679,2269,1052,1324,1723,897,366,4,524,30,757,1033,1479,1251,1550,79,3183,631
1.6773130953634898,0.6924087361167105,0.247687286863095,-0.394503221669089,2.0482786735043907,0.07884243567085535,1.3155174609171851,0.7381362515768051,3.0406193462815296,-0.8120509037528868,0.7152972491503666,-0.292924427202373,0.39020697451391223,0.22373886117967634,0.005600908079439391,0.507480352534478,1.1630605789...
3,643
Abnormal muscle fiber morphology
18
73
3.186761
0.001439
O95831,O43676,P03886,P50570,O60313,Q9H2D1,P02545,Q86U42,P06753,P50402,P07196,Q8WZ42,Q70HW3,P23786,P11047,Q99720,P05067,P35637
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
380,3,90,322,261,11,42,432,296,428,113,179,441,461,218,27,156,284
3114,826,3,1439,261,2175,1310,380,2591,1149,42,90,3557,156,296,113,1684,1883,218,2335,1844,1930,658,461,3170,2856,284,1407,1320,428,322,1717,2135,1891,2387,1851,929,1377,2751,1280,1806,3284,1856,2566,666,441,1059,1284,814,432,2841,1093,3083,1533,2050,2797,1779,179,1702,1244,27,1299,1173,3109,11,3331,1543,3227,2448,1676...
-0.9194313337399534,0.5540203428545035,4.573298093913296,0.1515514229907377,1.401701779928311,-0.2425328384980788,0.22373886117967634,1.1191099133204574,-0.4971701187929715,0.3191957867311709,2.871236707602699,2.1492621159839103,-1.7987265678678774,1.8022971674617145,1.3155174609171851,2.027977430849258,0.0300746159801...
3,643
Protein homodimerization activity
32
191
3.177475
0.001486
P09493,P23246,Q14849,O43707,P67936,O95684,Q15257,O00429,P27105,Q15276,Q04837,P35579,Q14108,O75150,Q8TBA6,P42892,Q9UPN4,P09601,P55327,Q99584,Q15070,Q9NWU2,P04818,P07602,P12814,Q03164,Q15075,O60749,Q8IY95,P12270,Q99623,O00264
Functions
GO Molecular function
msigdb_gomf
2,132,6,260,15,274,288,160,283,166,168,298,47,295,178,59,191,63,65,66,196,328,74,76,332,333,80,201,336,91,236,112
2499,2257,112,696,160,2879,1257,739,2116,918,260,1679,201,785,921,295,3064,2175,3392,3168,2076,1494,3300,887,274,1044,2181,74,2880,3440,2078,76,1313,512,495,2262,2,63,2458,2026,91,332,1315,1119,2821,1442,2263,2779,951,3608,3335,460,2081,132,2633,2854,283,3186,2339,1048,890,3038,2301,2745,2082,2595,2550,924,1270,298,122...
-0.445698559329321,-0.292924427202373,2.027977430849258,0.6924087361167105,1.781560842290383,-0.7059069408091564,0.247687286863095,0.6464819347119302,-0.21743476674892134,0.48413189400814893,1.401701779928311,0.03007461598016483,1.6143043553854377,0.6003533278278015,0.48413189400814893,1.3155174609171851,-0.86558396744...
3,643
Apical plasma membrane
21
49
3.171991
0.001514
Q9NV70,Q15043,O15439,P08183,Q16181,O75955,Q99808,P36551,P51790,P35241,Q86UE4,P11166,P26038,Q14254,Q9Y6M7,P53985,P30825,P15311,O15020,Q16625,P08238
Localization
GO Cellular component
msigdb_gocc
651,134,259,275,407,530,559,554,679,67,471,203,96,483,631,481,371,124,605,122,495
2775,856,605,259,1039,921,530,1069,698,1263,2413,275,1118,1684,495,203,2125,124,2222,1046,2264,2671,96,371,67,2128,554,2597,2637,679,481,2269,1052,1324,1445,3305,483,134,407,122,471,1698,1103,559,2105,651,3229,3525,631
-0.62708619656327,0.5307763897453316,0.7836669490667206,1.401701779928311,0.39020697451391223,0.48413189400814893,0.8741475129403571,0.3665912224666737,0.6924087361167105,0.247687286863095,-0.394503221669089,1.3802181900709822,0.34292094779173377,0.03007461598016483,0.9191020703510948,1.6143043553854377,-0.217434766748...
3,643
Lipid droplet
10
35
3.165019
0.001551
Q07065,Q01105,O43760,Q8NF37,P51572,Q9H6V9,Q8N0X7,Q9H4M9,Q99720,P07355
Localization
GO Cellular component
msigdb_gocc
36,58,446,433,276,17,506,154,27,494
2023,446,2072,1041,1637,2669,1967,494,1888,2783,3014,276,2677,2387,1080,58,36,1729,2434,1522,506,542,1334,433,1132,2797,1821,1242,1702,27,154,17,2105,782,3231
-0.16743166552350902,0.9861831680424349,-0.1924012006648247,0.39020697451391223,0.054488318052800216,-0.5489222320312916,-0.1425256923482076,0.9191020703510948,-0.09290258413901609,-0.62708619656327,-0.8120509037528868,1.3802181900709822,-0.5489222320312916,-0.3690078123018647,0.3665912224666737,2.583693325050595,2.965...
3,643
Hydrogen ion transport
9
20
3.158176
0.001588
O75964,P56385,P18859,Q15904,P06576,Q9Y487,Q9Y5K8,P24539,Q93050
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
35,482,75,366,109,79,180,219,30
1311,35,109,75,2264,2706,219,1316,572,2128,2597,2469,2429,482,1324,366,30,1550,79,180
0.22373886117967634,2.9844124544918555,2.0482786735043907,2.348682347368294,-0.292924427202373,-0.5749048809587229,1.5509437761405507,0.22373886117967634,0.8290032464607571,-0.21743476674892134,-0.4971701187929715,-0.4200666292018141,-0.394503221669089,0.9415089211120462,0.22373886117967634,1.1630605789708375,3.0965765...
3,643
Vesicle mediated transport
80
276
3.148545
0.001641
P24390,Q92845,P07900,P86790,Q9H9E3,Q14108,O14653,P83436,Q13561,P55327,O00461,Q96Q89,Q9UBW8,Q8IWJ2,Q13813,O15020,Q9Y3B3,O95721,Q9Y4L1,Q86Y91,Q9NV70,O75976,Q9UPT5,P62258,Q15363,Q12965,Q96A65,Q9Y6G9,Q8WTV0,P05067,Q15276,Q5VZE5,Q86VN1,O43237,Q8TBA6,Q9UP83,Q14203,P59998,P49257,O00291,Q01082,Q9P2W9,Q6NUQ1,Q92734,O60749,P3194...
Processes and pathways
Reactome Pathways
msigdb_reactome
1,525,512,534,564,47,550,575,576,65,87,622,628,619,105,605,653,119,126,646,651,127,135,136,137,638,139,671,150,156,166,169,685,672,178,711,189,701,194,696,206,210,731,734,201,213,726,715,721,724,224,238,746,256,278,273,298,305,329,323,322,330,347,345,341,374,372,391,393,406,435,427,442,474,472,463,464,502,500,499
1750,2115,1589,3006,2775,2067,696,1405,87,947,972,2851,550,1678,605,2170,1633,3416,1361,1840,672,2023,715,2118,1962,1041,201,330,921,2073,273,127,1843,1792,2668,1496,224,1966,2178,119,858,3640,1044,2547,156,512,1795,2881,1190,2593,2778,1150,305,3346,1929,1762,950,2463,2979,3361,1,768,2338,3536,2635,1716,213,2302,238,29...
-0.01893323196983534,-0.21743476674892134,0.07884243567085535,-0.8120509037528868,-0.62708619656327,-0.1924012006648247,0.6924087361167105,0.17567132034205288,2.2294317463628888,0.46073067332952794,0.43727634598424736,-0.6795594013194657,0.8515992373556479,0.03007461598016483,0.7836669490667206,-0.2425328384980788,0.05...
3,643
Programmed cell death
39
103
3.1475
0.001647
P62258,O60313,Q13464,P51572,P07900,P08670,Q9UNM6,O00231,P28482,Q13177,O75955,P51665,O00429,Q15149,P02545,P27361,O60443,Q15008,P20700,O43242,P48556,P26583,P49354,Q07021,Q13546,P31946,P28070,P63104,Q07157,P62191,P62195,Q16543,Q14254,Q13813,O00233,P61981,Q16625,Q04917,P17980
Processes and pathways
Reactome Pathways
msigdb_reactome
136,261,640,276,512,19,800,271,659,287,530,661,160,538,42,297,674,577,57,309,700,450,68,335,595,213,589,463,341,221,722,484,483,105,604,500,122,748,496
271,2586,604,3254,160,1438,2332,2289,1961,1878,309,261,674,3480,530,2589,42,2628,1969,512,19,831,3261,2460,3393,3067,496,2594,57,2507,1010,2183,3097,450,2338,297,2382,589,1687,2823,659,2225,1716,213,1501,1225,3099,2509,1598,2132,700,2083,68,3486,1602,276,661,3141,2982,2555,3571,2640,787,500,221,722,136,2187,463,3236,19...
1.3802181900709822,-0.4971701187929715,0.7836669490667206,-1.0829137074111654,1.781560842290383,0.1515514229907377,-0.34357988327025807,-0.3182189232285267,-0.1425256923482076,-0.09290258413901609,1.2721729993532975,1.401701779928311,0.7152972491503666,-1.5341498793287338,0.8741475129403571,-0.4971701187929715,2.871236...
3,643
Rhobtb gtpase cycle
16
30
3.145209
0.00166
P38159,O75116,Q16543,P78371,Q8N684,Q13464,P12814,P08238,P07900,P08670,Q9BT78,Q13098,Q9NYL9,Q13618,P62995,Q8IYB3
Processes and pathways
Reactome Pathways
msigdb_reactome
161,282,484,681,473,640,332,495,512,19,347,502,546,811,788,842
1924,282,512,1007,495,19,332,161,2226,864,788,681,502,640,811,1514,1940,484,2090,2356,2756,842,473,3023,1700,1913,1914,347,546,2112
-0.11768281781113353,1.358693095009029,0.8966483619769324,0.41376856372481113,0.9191020703510948,3.445373456333539,1.2286577968396193,1.781560842290383,-0.26769589647874387,0.5307763897453316,0.6003533278278015,0.7152972491503666,0.9191020703510948,0.7609260502934108,0.5772125455062541,0.1273735787791028,-0.11768281781...
3,643
Alcohol binding
6
19
3.144231
0.001665
P45880,Q14849,P21796,Q14108,Q9BZF3,O15118
Functions
GO Molecular function
msigdb_gomf
352,6,77,47,49,50
2021,50,2119,804,1117,888,77,2506,1367,2466,1224,352,429,47,2189,6,1731,2103,49
-0.16743166552350902,2.6802893561721626,-0.21743476674892134,0.5772125455062541,0.34292094779173377,0.507480352534478,2.3090642821729386,-0.445698559329321,0.19973366863516875,-0.4200666292018141,0.2715793302199121,1.184969903794314,1.030673311900084,2.7187157574403082,-0.2425328384980788,4.338172746316298,0.0056009080...
3,643
Signaling by alk in cancer
15
36
3.143124
0.001672
P26038,P18206,Q13616,O00291,Q8IWJ2,P35579,P27361,P06753,P67936,Q92734,Q9P2E9,P33176,P28482,P12270,Q14203
Processes and pathways
Reactome Pathways
msigdb_reactome
96,164,300,696,619,298,297,296,15,734,338,238,659,91,189
696,1881,1792,2078,296,1595,91,164,1798,96,2223,297,659,2595,238,298,2509,894,1692,2600,2231,724,2431,15,1081,836,2751,300,189,1522,3424,619,734,1867,3057,338
0.6924087361167105,-0.09290258413901609,-0.04352823551645443,-0.1924012006648247,1.3155174609171851,0.07884243567085535,2.1492621159839103,1.7607870381690778,-0.04352823551645443,2.108972604755291,-0.26769589647874387,1.3155174609171851,0.7381362515768051,-0.4971701187929715,1.4872256449003394,1.3155174609171851,-0.445...
3,643
Cytosolic transport
20
74
3.141609
0.00168
Q86VS8,Q96ED9,Q8IUD2,P27361,O75503,Q9P2D3,Q14203,P49257,P35241,Q8N1B4,Q15075,O60749,Q9UNH7,P26038,O95249,Q8IWJ2,O60271,Q96QK1,P33176,P15311
Processes and pathways
GO Biological process
msigdb_gobp
149,424,43,297,181,583,189,194,67,472,80,201,629,96,224,619,477,241,238,124
2542,1678,1361,1840,715,477,2703,201,1491,1363,2074,181,1043,224,858,2379,2778,1315,124,1762,950,3335,96,297,659,238,67,3263,892,194,3014,1693,1123,2709,1767,2136,1081,1512,2834,1082,1896,2986,189,80,1576,1452,1528,149,43,619,472,1821,2278,424,1537,241,1702,1660,2060,2000,1663,2247,1870,583,1918,2908,1838,3414,2772,629...
-0.47139954319819993,0.03007461598016483,0.19973366863516875,-0.06818453902065648,0.6694704024024033,0.9415089211120462,-0.5749048809587229,1.6143043553854377,0.1273735787791028,0.19973366863516875,-0.1924012006648247,1.6773130953634898,0.39020697451391223,1.5297444135769949,0.5307763897453316,-0.3690078123018647,-0.62...
3,643
Structural constituent of cytoskeleton
19
37
3.14046
0.001687
Q16352,P09493,Q9UEY8,P08670,P35612,P07197,Q15149,O95619,P59998,O00291,Q01082,P23258,Q9BVA1,Q16204,P26038,Q13813,P07196,O15020,Q9Y2J2
Functions
GO Molecular function
msigdb_gomf
254,2,400,19,660,26,538,52,701,696,206,832,877,356,96,105,113,605,911
696,605,1633,3416,52,2547,113,26,1758,19,2,1639,2460,832,96,660,701,3267,2136,2087,206,3075,105,2037,3104,538,356,254,1579,3451,1999,2403,877,400,911,1486,914
0.6924087361167105,0.7836669490667206,0.054488318052800216,-1.3622032056549125,2.66103099844741,-0.47139954319819993,2.027977430849258,3.1522873279909853,-0.01893323196983534,3.445373456333539,4.771723202663586,0.054488318052800216,-0.4200666292018141,0.5540203428545035,2.108972604755291,0.7381362515768051,0.6924087361...
3,643
Ion transport
20
56
3.130774
0.001743
Q9UM00,Q15043,Q93050,O75964,Q9C0H2,O95202,Q9Y5K8,P51790,P04920,P36542,P18859,P21796,Q9Y487,P24539,P45880,P56385,Q9Y6M7,Q15904,P06576,Q6P4Q7
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
528,134,30,35,689,413,180,679,698,572,75,77,79,219,352,482,631,366,109,245
3255,1311,35,413,2591,698,1263,2413,109,1594,744,75,1046,2264,2706,77,2671,219,1316,572,2128,2597,352,2469,679,1079,2269,1052,2429,482,1324,1695,2189,134,366,2838,2955,245,2198,2441,2051,30,1540,1299,2527,689,1390,1431,1550,528,2623,3229,79,180,3183,631
-1.0829137074111654,0.22373886117967634,2.9844124544918555,1.0528500237537732,-0.4971701187929715,0.6924087361167105,0.247687286863095,-0.394503221669089,2.0482786735043907,0.07884243567085535,0.6464819347119302,2.348682347368294,0.39020697451391223,-0.292924427202373,-0.5749048809587229,2.3090642821729386,-0.548922232...
3,643
Respirasome
13
48
3.124876
0.001779
Q9P0J0,O43676,P03886,P13073,P14406,P22695,Q9UDW1,Q6DKK2,Q13423,O14949,Q16718,P14927,Q9Y6M9
Localization
GO Cellular component
msigdb_gocc
34,3,90,104,10,81,18,318,53,115,316,92,258
359,3114,1146,115,3,2973,3036,829,2588,1004,1591,1495,3577,2334,2077,1149,90,767,513,1970,104,10,2028,92,2705,2548,3569,1074,2464,81,3394,3170,1688,3408,1976,53,316,775,318,3606,1332,3022,873,3182,34,18,1676,258
1.1630605789708375,-0.9194313337399534,0.3191957867311709,2.007640931103598,4.573298093913296,-0.7854005981288927,-0.838778477489919,0.5540203428545035,-0.4971701187929715,0.41376856372481113,0.07884243567085535,0.1273735787791028,-1.8888027743308256,-0.34357988327025807,-0.1924012006648247,0.3191957867311709,2.1492621...
3,643
Ire1alpha activates chaperones
12
28
3.116125
0.001832
O14773,P49840,Q14999,Q9UBS4,Q9NWM8,P02545,O43909,O14653,P43307,O95070,Q14203,Q9Y4L1
Processes and pathways
Reactome Pathways
msigdb_reactome
162,636,536,211,107,42,606,550,54,250,189,126
550,162,606,633,1792,250,42,2261,1225,54,2675,636,3173,1324,1377,1278,189,1516,536,1125,2795,1738,3027,107,211,1486,126,1113
0.8515992373556479,1.7607870381690778,0.7836669490667206,0.7609260502934108,-0.04352823551645443,1.4445453596918503,2.871236707602699,-0.292924427202373,0.2715793302199121,2.6224232866935613,-0.5489222320312916,0.7609260502934108,-0.9735983713191992,0.22373886117967634,0.19973366863516875,0.247687286863095,1.6563489288...
3,643
Steroid biosynthetic process
14
49
3.106938
0.00189
Q15392,Q9UKR5,Q14849,P16435,Q15800,Q9UBM7,P14324,Q53GQ0,P37268,Q9BZF3,Q16850,Q8NBQ5,Q14739,Q13510
Processes and pathways
GO Biological process
msigdb_gobp
420,401,6,570,40,369,478,616,16,49,240,542,23,158
2776,1752,804,1148,1117,2669,1312,1263,2026,478,2419,570,2300,2506,2978,1048,2466,16,3012,1888,1977,1567,1322,2861,1982,2711,158,2835,641,23,6,420,1163,1899,2434,40,240,616,542,3155,1621,3355,2661,49,2210,369,1748,1252,401
-0.62708619656327,-0.01893323196983534,0.5772125455062541,0.3191957867311709,0.34292094779173377,-0.5489222320312916,0.22373886117967634,0.247687286863095,-0.16743166552350902,0.9415089211120462,-0.394503221669089,0.8290032464607571,-0.3182189232285267,-0.445698559329321,-0.7854005981288927,0.39020697451391223,-0.42006...
3,643
SLC superfamily of solute carriers
15
43
3.103893
0.00191
Q15043,Q9Y6M7,O95202,P53985,Q99808,Q9H2D1,Q8TB61,P11166,Q9H0U3,Q8IXU6,Q9UBX3,Q70HW3,P30825,Q9BSK2,O43772
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
134,631,413,481,559,11,173,203,242,177,86,441,371,649,61
1256,1752,61,1183,2025,413,2503,698,2670,1118,203,2335,2632,371,2135,481,1052,2645,2390,134,1414,2955,1941,1524,441,177,173,1031,559,649,1426,242,11,2965,1544,1344,1141,86,2013,3229,2167,946,631
0.247687286863095,-0.01893323196983534,2.4863261827117857,0.2954153714992455,-0.16743166552350902,1.0528500237537732,-0.445698559329321,0.6924087361167105,-0.5489222320312916,0.34292094779173377,1.6143043553854377,-0.34357988327025807,-0.5230108310595,1.1411073335741186,-0.21743476674892134,0.9415089211120462,0.3902069...
3,643
Secretory granule membrane
21
76
3.102276
0.00192
Q15363,O15439,P30519,Q93050,P27105,P42785,Q5T9A4,Q07065,Q8NF37,Q9BXS5,P49755,Q9Y5K8,Q13576,P35613,Q969Q5,P07602,P10253,Q9H0U3,O00264,O15121,O95721
Localization
GO Cellular component
msigdb_gocc
137,259,13,30,283,32,292,36,433,435,427,180,439,64,453,76,231,242,112,116,119
3006,112,1752,116,803,1361,259,675,716,2333,1491,1714,1843,119,3260,76,231,2416,1314,2379,2593,1191,2460,2915,699,950,283,13,3139,2340,64,1318,32,634,427,2783,3014,1718,2428,2304,3279,1767,3593,2641,2305,3236,2346,2476,36,2834,439,1450,483,2189,137,2838,3177,292,813,433,2758,990,30,453,1658,1296,3474,435,242,2105,1141,...
-0.8120509037528868,2.027977430849258,-0.01893323196983534,2.007640931103598,0.5772125455062541,0.19973366863516875,1.401701779928311,0.7152972491503666,0.6694704024024033,-0.34357988327025807,0.1273735787791028,0.005600908079439391,-0.06818453902065648,1.9872689975161881,-1.0829137074111654,2.3090642821729386,1.508505...
3,643
Functional motor deficit
37
161
3.092153
0.001987
Q9H0B6,Q969G3,Q9H2D1,Q9Y2R0,Q13510,Q99720,Q9Y285,P35240,Q15149,O00429,P35637,O14773,P06753,O14653,Q8WZ42,Q9UGM6,P20700,P40939,P50570,P07602,Q07021,Q8TD16,P23786,P03886,P11047,P46020,Q12768,Q9NWM8,O43292,P51530,Q96QK1,Q14683,P07196,O00217,Q8N0X7,P61981,Q15041
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
256,130,11,21,158,27,290,157,538,160,284,162,296,550,179,584,57,573,322,76,335,345,461,90,218,220,342,107,360,364,241,503,113,359,506,500,125
1114,359,160,2070,550,162,360,673,2454,1491,2175,804,3008,1441,2502,3259,1149,2180,90,859,2181,296,113,3094,76,1684,3095,1595,218,2335,1191,1844,3212,57,2464,2854,461,1972,2672,2029,3536,2781,3170,2856,157,284,1503,2782,2597,573,3042,2185,1320,220,1975,1641,322,364,2600,2135,3101,2229,2387,1803,2858,1851,500,1081,2088,...
0.34292094779173377,1.1630605789708375,1.781560842290383,-0.1924012006648247,0.8515992373556479,1.7607870381690778,1.1630605789708375,0.7152972491503666,-0.4200666292018141,0.1273735787791028,-0.2425328384980788,0.5772125455062541,-0.8120509037528868,0.1515514229907377,-0.445698559329321,-1.0829137074111654,0.319195786...
3,643
Chemical homeostasis
42
190
3.070059
0.00214
Q92544,Q16891,Q8N511,Q9UM00,Q9Y4W6,Q15043,P62258,P16949,P30519,P51572,Q9UJZ1,Q8WTV0,O15254,Q9H4M9,P05067,Q93050,Q15149,P42785,P50897,Q9NQC3,O95202,Q96A33,Q96CP7,Q8NF37,P27361,P61916,O15118,O75503,P09601,Q9Y487,P17480,Q9HD20,O60826,P05771,Q9HCL2,Q5BJF2,P12277,P53985,Q15904,P06576,P0DP25,Q6P4Q7
Processes and pathways
GO Biological process
msigdb_gobp
524,255,4,528,529,134,136,12,13,276,549,150,272,154,156,30,538,32,31,425,413,301,434,433,297,429,50,181,63,79,204,85,459,340,229,97,95,481,366,109,110,245
2775,2067,1960,1488,856,50,949,272,1361,2454,675,459,785,181,1364,3555,633,3495,413,3300,1966,2503,1406,3640,1044,859,3483,2218,698,1263,2413,156,340,109,786,1366,3066,1188,888,1684,831,63,1561,1594,110,95,2778,1266,1150,2419,744,12,2420,2298,204,2126,1798,3212,1046,2080,2300,2671,297,3068,3536,2339,1800,659,2780,13,24...
-0.62708619656327,-0.1924012006648247,-0.1425256923482076,0.1273735787791028,0.5307763897453316,2.6802893561721626,0.46073067332952794,1.3802181900709822,0.19973366863516875,-0.4200666292018141,0.7152972491503666,0.9638691945115666,0.6003533278278015,1.6773130953634898,0.19973366863516875,-1.7987265678678774,0.76092605...
3,643
Polymeric cytoskeletal fiber
69
203
3.046533
0.002315
Q9H0B6,Q16352,Q92845,P09493,Q9UPN3,P46940,Q9Y2A7,O75449,Q12965,P16949,O60313,Q9Y6G9,P67936,A0MZ66,P08670,Q86VS8,Q9Y496,P07197,Q03252,Q14980,Q15149,O00429,Q96ED9,Q9UQB8,Q03001,P02545,P06753,O43237,O43663,O95613,O95816,P50402,Q9Y448,P78371,P20700,Q13618,P48681,Q14203,Q13561,Q6IBS0,P50570,Q5M775,O94927,P12814,P23258,Q9BSJ...
Localization
GO Cellular component
msigdb_gocc
256,254,525,2,402,634,910,262,638,12,261,671,15,387,19,149,802,26,29,419,538,160,424,695,431,42,296,672,551,676,805,428,445,681,57,811,314,189,576,707,322,466,331,332,832,735,836,217,876,877,622,492,488,867,855,617,110,739,113,238,252,613,908,493,905,383,124,648,646
387,2115,855,1589,160,2625,3033,739,672,2023,551,2117,1219,261,2118,2024,1186,262,331,2668,1496,676,805,2546,3092,42,1069,2547,493,296,113,26,1758,2295,19,2,110,332,2778,1266,3628,2821,124,2460,12,1971,57,832,3138,2224,3038,238,3316,2226,925,1599,2857,634,2887,314,1272,1444,428,322,3043,1642,1889,1122,1849,3511,613,349...
1.097068061484193,-0.21743476674892134,0.5307763897453316,0.07884243567085535,1.781560842290383,-0.5230108310595,-0.838778477489919,0.6464819347119302,0.7152972491503666,-0.16743166552350902,0.8515992373556479,-0.21743476674892134,0.2715793302199121,1.401701779928311,-0.21743476674892134,-0.16743166552350902,0.29541537...
3,643
Cancer-related genes
109
435
3.042622
0.002345
P09493,Q14849,Q9BQE5,Q99595,P62841,P16949,P14174,P67936,P07900,P80303,P98175,P43490,Q15149,P00374,Q8IUD2,P02545,O75533,Q99543,Q01105,P09601,P55327,Q15233,Q86UP2,Q06136,P04818,Q96AE4,O43290,P12270,Q8NFG4,Q8WYA6,P26038,P12277,Q9NYF8,O75962,P67809,P15311,Q86U86,Q969G3,P23246,P60228,P49840,P62258,P49736,Q86VS8,P28482,P2262...
Functions
Protein Atlas Protein class
protein_atlas_protein_class
2,6,7,8,520,12,514,15,512,22,24,533,538,531,43,42,552,580,58,63,65,70,71,69,74,600,587,91,620,621,96,95,627,118,121,124,645,130,132,133,636,136,635,149,659,658,656,157,161,166,675,175,682,178,185,680,188,189,702,195,193,699,696,704,729,203,734,200,213,218,716,721,228,232,239,238,263,275,274,289,284,300,298,297,296,304,...
2115,2331,696,3255,1960,972,1000,1489,200,2289,2700,2625,2879,3033,1753,949,2972,975,587,3516,1881,2940,2173,675,783,716,784,2974,921,828,2292,2258,552,1492,2076,118,2412,263,2545,1365,1637,274,2546,2293,3259,531,2669,3344,2977,3260,42,1044,3557,3504,1069,3483,3578,1682,2628,2181,74,193,1263,3430,340,1683,493,2820,3440...
-0.21743476674892134,-0.34357988327025807,0.6924087361167105,-1.0829137074111654,-0.1425256923482076,0.43727634598424736,0.41376856372481113,0.1273735787791028,1.6143043553854377,-0.3182189232285267,-0.5749048809587229,-0.5230108310595,-0.7059069408091564,-0.838778477489919,-0.01893323196983534,0.46073067332952794,-0.7...
3,643
Cancer-related genes
109
435
3.042622
0.002345
P09493,Q14849,Q9BQE5,Q99595,P62841,P16949,P14174,P67936,P07900,P80303,P98175,P43490,Q15149,P00374,Q8IUD2,P02545,O75533,Q99543,Q01105,P09601,P55327,Q15233,Q86UP2,Q06136,P04818,Q96AE4,O43290,P12270,Q8NFG4,Q8WYA6,P26038,P12277,Q9NYF8,O75962,P67809,P15311,Q86U86,Q969G3,P23246,P60228,P49840,P62258,P49736,Q86VS8,P28482,P2262...
Drugs and Diseases
Protein Atlas Disease involvement
protein_atlas_disease_involvement
2,6,7,8,520,12,514,15,512,22,24,533,538,531,43,42,552,580,58,63,65,70,71,69,74,600,587,91,620,621,96,95,627,118,121,124,645,130,132,133,636,136,635,149,659,658,656,157,161,166,675,175,682,178,185,680,188,189,702,195,193,699,696,704,729,203,734,200,213,218,716,721,228,232,239,238,263,275,274,289,284,300,298,297,296,304,...
2115,2331,696,3255,1960,972,1000,1489,200,2289,2700,2625,2879,3033,1753,949,2972,975,587,3516,1881,2940,2173,675,783,716,784,2974,921,828,2292,2258,552,1492,2076,118,2412,263,2545,1365,1637,274,2546,2293,3259,531,2669,3344,2977,3260,42,1044,3557,3504,1069,3483,3578,1682,2628,2181,74,193,1263,3430,340,1683,493,2820,3440...
-0.21743476674892134,-0.34357988327025807,0.6924087361167105,-1.0829137074111654,-0.1425256923482076,0.43727634598424736,0.41376856372481113,0.1273735787791028,1.6143043553854377,-0.3182189232285267,-0.5749048809587229,-0.5230108310595,-0.7059069408091564,-0.838778477489919,-0.01893323196983534,0.46073067332952794,-0.7...
3,643
Plasma membrane region
62
208
3.020067
0.002527
Q8NCG7,Q92845,P09493,Q9NV70,Q9UPN3,Q15043,Q9BTU6,P46939,Q53EZ4,Q12965,O15439,Q96D71,O75935,P08183,Q8WTV0,P35612,P28482,Q9H4M9,Q99720,Q16181,P05067,O75955,P35240,O00429,Q9UQB8,Q03001,Q99808,Q8IUD2,O60610,P35579,P36551,P27361,P51790,P40855,P09601,P35613,Q9UNF0,P04920,Q01082,P35241,P50570,Q86UE4,P11166,Q14141,Q15019,P3558...
Localization
GO Cellular component
msigdb_gocc
523,525,2,651,402,134,399,518,138,638,259,278,273,275,150,660,659,154,27,407,156,530,157,160,695,431,559,43,675,298,554,297,679,313,63,64,329,698,206,67,322,471,203,596,465,214,341,96,483,631,481,371,495,605,613,245,374,122,497,119,124,494
1589,2775,696,160,856,2625,948,605,1633,259,1881,1039,675,2024,921,3036,273,530,1043,1843,2668,979,119,858,3640,1044,1069,698,1263,2413,156,3430,1366,494,275,1118,1684,495,3543,2,1795,2881,63,1595,2378,1190,203,1639,2778,1928,2125,1119,2821,124,3535,2460,2298,2126,3346,2222,1798,1046,2264,2979,1715,3454,2671,2182,96,29...
0.07884243567085535,-0.62708619656327,0.6924087361167105,1.781560842290383,0.5307763897453316,-0.5230108310595,0.46073067332952794,0.7836669490667206,0.054488318052800216,1.401701779928311,-0.09290258413901609,0.39020697451391223,0.7152972491503666,-0.16743166552350902,0.48413189400814893,-0.838778477489919,1.380218190...
3,643
Endoplasmic reticulum golgi intermediate compartment membrane
10
27
3.015159
0.002568
P24390,Q9Y282,Q8N511,P49257,Q15363,Q15904,P51572,P49755,O14653,O95070
Localization
GO Cellular component
msigdb_gocc
1,99,4,194,137,366,276,427,550,250
550,1361,1840,1880,2073,250,1,3536,194,427,276,771,1570,1227,1448,1082,137,366,4,815,1469,2060,2766,1136,99,970,653
0.8515992373556479,0.19973366863516875,-0.06818453902065648,-0.09290258413901609,-0.1924012006648247,1.4445453596918503,5.128435927033103,-1.7096113970661815,1.6353460842060628,1.030673311900084,1.3802181900709822,0.6234430164808086,0.10313738534059588,0.2715793302199121,0.1515514229907377,0.3665912224666737,1.90542333...
3,643
Muscle contraction
9
30
3.012461
0.002591
Q05682,P09493,P18206,P06753,P67936,P08670,Q8WZ42,Q13177,P07355
Processes and pathways
Reactome Pathways
msigdb_reactome
381,2,164,296,15,19,179,287,494
1039,1069,1263,2413,296,494,888,19,2,744,2298,2126,164,1046,2671,2224,3139,1565,2269,2430,15,381,2712,287,1984,2189,2609,179,546,1486
0.39020697451391223,0.3665912224666737,0.247687286863095,-0.394503221669089,1.3155174609171851,0.9191020703510948,0.507480352534478,3.445373456333539,4.771723202663586,0.6464819347119302,-0.3182189232285267,-0.21743476674892134,1.7607870381690778,0.39020697451391223,-0.5489222320312916,-0.26769589647874387,-0.946474552...
3,643
Sphingolipid metabolic process
10
30
3.010803
0.002606
Q96G23,Q8NCC3,Q06136,P07602,P17900,O15269,Q6Y1H2,O15121,Q13510,P50897
Processes and pathways
GO Biological process
msigdb_gobp
131,197,69,76,515,388,408,116,158,31
116,388,1634,718,859,2880,2121,76,3066,1442,515,2300,553,952,31,69,158,1811,408,1286,197,131,778,1479,1670,1036,1141,1433,2875,1791
2.007640931103598,1.097068061484193,0.054488318052800216,0.6694704024024033,0.5307763897453316,-0.7059069408091564,-0.21743476674892134,2.3090642821729386,-0.86558396744226,0.1515514229907377,0.8966483619769324,-0.3182189232285267,0.8515992373556479,0.46073067332952794,3.0406193462815296,2.4078652087559544,1.8022971674...
3,643
Alzheimers disease
15
67
2.997149
0.002725
O43676,P13073,P14406,P18859,P27361,P06576,P0DP25,P22695,Q9UDW1,O14949,Q16718,P24539,P14927,P05067,Q9Y6M9
Processes and pathways
KEGG Pathways
msigdb_kegg
3,104,10,75,297,109,110,81,18,115,316,219,92,156,258
2068,359,3114,1146,2289,115,3,2973,3036,829,2588,1004,1591,1311,1495,3577,2334,2077,1149,1967,156,109,3094,767,513,110,1970,104,10,1119,2028,92,2705,744,2548,2127,75,3569,1074,2464,81,219,1316,297,3394,659,3170,1688,572,1598,2469,2083,3408,2676,1976,2555,1445,2749,664,2189,316,775,990,3355,18,1251,258
-0.1924012006648247,1.1630605789708375,-0.9194313337399534,0.3191957867311709,-0.3182189232285267,2.007640931103598,4.573298093913296,-0.7854005981288927,-0.838778477489919,0.5540203428545035,-0.4971701187929715,0.41376856372481113,0.07884243567085535,0.22373886117967634,0.1273735787791028,-1.8888027743308256,-0.343579...
3,643
Dysphagia
39
146
2.99456
0.002748
Q9UPN3,Q9UEY8,Q9Y4W6,Q8IZA0,O60313,Q96D71,Q14739,Q99720,Q13510,P05067,Q9UHX1,P35240,Q15149,O00429,P35637,Q86U42,P06753,Q14108,P61916,P15586,O15118,Q9UGM6,Q01105,P20700,Q14203,O60220,Q15233,Q8N3U4,P07602,Q03164,P17480,P03886,P11047,Q8NFG4,Q14683,Q96QK1,O95155,Q8N0X7,P25490
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
402,400,529,267,261,278,23,27,158,156,548,157,538,160,284,432,296,47,429,305,50,584,58,57,189,436,70,324,76,333,204,90,218,620,503,241,607,506,612
160,2070,1360,50,739,2454,436,261,1491,829,1591,3168,2076,633,1117,1792,607,3300,887,2819,90,859,2547,156,296,76,3585,1313,1497,2079,218,2882,2335,305,204,2381,1761,57,2299,2464,612,2634,3394,3038,2781,3170,157,284,2782,2552,925,2185,1320,2948,2600,2135,2229,1051,1052,2387,2858,1568,3191,429,2232,1606,2950,2785,1081,58...
1.781560842290383,-0.1924012006648247,0.19973366863516875,2.6802893561721626,0.6464819347119302,-0.4200666292018141,1.0084511164761645,1.401701779928311,0.1273735787791028,0.5540203428545035,0.07884243567085535,-0.9735983713191992,-0.1924012006648247,0.7609260502934108,0.34292094779173377,-0.04352823551645443,0.7836669...
3,643
Sterol binding
6
18
2.974872
0.002931
P45880,Q14849,P21796,Q14108,Q9BZF3,O15118
Functions
GO Molecular function
msigdb_gomf
352,6,77,47,49,50
50,804,1117,888,77,2300,2506,2466,1224,352,429,2711,47,6,1621,2208,2103,49
2.6802893561721626,0.5772125455062541,0.34292094779173377,0.507480352534478,2.3090642821729386,-0.3182189232285267,-0.445698559329321,-0.4200666292018141,0.2715793302199121,1.184969903794314,1.030673311900084,-0.5749048809587229,2.7187157574403082,4.338172746316298,0.07884243567085535,-0.2425328384980788,-0.19240120066...
3,643
Intra golgi and retrograde golgi to er traffic
30
106
2.971869
0.00296
Q9H0B6,P24390,Q92845,Q15363,Q13439,Q9Y6G9,O75935,Q9H9E3,Q5VZE5,O43237,Q8TBA6,O14653,P49755,Q9UP83,Q14203,P83436,Q13561,Q9P2W9,Q8N1B4,Q8TD16,O00461,P82094,Q96Q89,O95249,Q8IWJ2,P33176,P52907,Q9Y3B3,O95721,Q86Y91
Processes and pathways
Reactome Pathways
msigdb_reactome
256,1,525,137,391,671,273,564,169,672,178,550,427,711,189,575,576,210,472,345,87,464,622,224,619,238,499,653,119,646
1750,2115,87,2851,550,1361,1840,672,2023,2118,1041,2073,273,2668,1496,224,119,2547,2593,3346,950,2463,1,238,1502,3263,1599,1507,2554,2980,893,427,1693,1122,499,2428,3142,1373,926,746,2033,3236,2087,3337,464,575,2860,1645,836,1609,1227,2834,1610,1082,1648,391,576,2037,189,1806,1573,2789,897,1729,1328,137,1019,169,731,64...
-0.01893323196983534,-0.21743476674892134,2.2294317463628888,-0.6795594013194657,0.8515992373556479,0.19973366863516875,-0.06818453902065648,0.7152972491503666,-0.16743166552350902,-0.21743476674892134,0.39020697451391223,-0.1924012006648247,1.3802181900709822,-0.5489222320312916,0.1273735787791028,1.5297444135769949,1...
3,643
Phospholipid binding
36
105
2.971798
0.002961
Q9NV70,P46940,Q12965,O60313,Q9UJZ1,Q8WTV0,Q14677,Q14980,A0FGR8,P50897,O14773,Q00169,Q86VN1,Q14108,O60443,Q9UM22,Q13576,Q6IBS0,Q9UNF0,Q8NCC3,P20073,O00291,Q01082,Q92783,P07602,P21796,Q15075,O60749,O60784,Q9UNH7,P45880,Q9H4A5,Q15036,O43292,O15020,P07355
Functions
GO Molecular function
msigdb_gomf
651,634,638,261,549,150,406,419,654,31,162,418,685,47,674,55,439,707,329,197,699,696,206,474,76,77,80,201,716,629,352,368,752,360,605,494
654,696,1405,2332,162,605,1878,360,1219,261,674,2703,201,716,2333,921,1069,494,76,3585,888,831,1927,1190,1639,2027,699,2299,77,2300,3509,3395,2782,2637,352,2857,634,1640,3580,31,3264,1123,418,206,638,2036,2561,439,1896,47,2189,406,419,752,80,1731,707,1858,1653,3339,685,1091,1735,2723,197,3129,150,1821,1240,474,776,2492...
0.7381362515768051,0.6924087361167105,0.17567132034205288,-0.34357988327025807,1.7607870381690778,0.7836669490667206,-0.09290258413901609,1.1630605789708375,0.2715793302199121,1.401701779928311,0.7152972491503666,-0.5749048809587229,1.6143043553854377,0.6694704024024033,-0.34357988327025807,0.48413189400814893,0.366591...
3,643
Translocation
14
53
2.960641
0.00307
Q9NS69,Q9Y584,O60830,Q9BTX1,Q99595,Q15629,O75381,Q9P2E9,Q8NFH4,P41208,Q8TD16,P12270,O60220,Q8N1F7
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
0,73,5,294,8,106,202,338,277,93,345,91,436,343
1589,2169,976,436,5,202,2501,91,1597,2782,93,3069,1692,2343,2892,770,3621,3629,2473,3319,2232,1572,106,2990,1731,1812,958,470,343,3052,277,3129,345,1290,1169,2759,1292,1294,2153,1659,8,294,560,2660,2967,0,338,3252,2850,73,1555,825,2165
0.07884243567085535,-0.2425328384980788,0.43727634598424736,1.0084511164761645,4.4394304513124805,1.6143043553854377,-0.445698559329321,2.1492621159839103,0.07884243567085535,-0.62708619656327,2.1492621159839103,-0.86558396744226,0.03007461598016483,-0.34357988327025807,-0.7059069408091564,0.6234430164808086,-2.3547242...
3,643
Cholesterol binding
6
14
2.944961
0.00323
P45880,Q14849,P21796,Q14108,Q9BZF3,O15118
Functions
GO Molecular function
msigdb_gomf
352,6,77,47,49,50
50,804,1117,888,77,2506,2466,1224,352,429,47,6,2103,49
2.6802893561721626,0.5772125455062541,0.34292094779173377,0.507480352534478,2.3090642821729386,-0.445698559329321,-0.4200666292018141,0.2715793302199121,1.184969903794314,1.030673311900084,2.7187157574403082,4.338172746316298,-0.1924012006648247,2.6995175640331244
3,643
Huntingtons disease
17
83
2.943494
0.003245
O43676,P45880,P13073,P14406,P18859,P21796,P06576,Q00059,P22695,Q9UDW1,O15514,O14949,Q16718,P24539,P14927,Q14203,Q9Y6M9
Processes and pathways
KEGG Pathways
msigdb_kegg
3,352,104,10,75,77,109,145,81,18,212,115,316,219,92,189,258
359,696,3114,1146,2289,115,212,3,2973,3036,829,2588,1004,1591,1311,1843,1495,3577,2334,858,2077,1149,3483,2628,2670,109,767,1795,2881,513,1970,2335,2632,104,10,2028,92,2705,2548,75,2947,3569,1074,77,2464,81,219,1972,1316,3068,3394,1846,3170,1688,572,1598,2185,352,2469,3408,1976,1605,2949,3601,2475,1124,145,1081,1608,22...
1.1630605789708375,0.6924087361167105,-0.9194313337399534,0.3191957867311709,-0.3182189232285267,2.007640931103598,1.593223534541233,4.573298093913296,-0.7854005981288927,-0.838778477489919,0.5540203428545035,-0.4971701187929715,0.41376856372481113,0.07884243567085535,0.22373886117967634,-0.06818453902065648,0.12737357...
3,643
Mitochondrial membrane organization
15
53
2.937209
0.003312
Q9NS69,Q15070,Q16891,Q9P0J0,Q9Y584,P45880,Q9Y4W6,O95202,O60313,P0DP25,Q9UII2,Q9NX63,O75431,O14737,O60220
Processes and pathways
GO Biological process
msigdb_gobp
0,196,255,34,73,352,529,413,261,110,350,253,404,60,436
2067,60,436,261,921,404,1842,1441,413,2628,2670,512,2629,110,2335,1760,3469,2225,2383,2636,3012,352,1801,636,2676,2267,2471,749,196,255,2990,1811,3197,1990,792,2689,3127,962,3290,3388,1138,0,1787,253,34,350,1676,529,1403,73,1555,825,2165
-0.1924012006648247,2.4863261827117857,1.0084511164761645,1.401701779928311,0.48413189400814893,1.074981518864855,-0.06818453902065648,0.1515514229907377,1.0528500237537732,-0.5230108310595,-0.5489222320312916,0.8966483619769324,-0.5230108310595,2.0482786735043907,-0.34357988327025807,-0.01893323196983534,-1.5052535177...
3,643
Steroid biosynthesis
9
23
2.936128
0.003323
Q15392,Q9UKR5,Q15800,Q9UBM7,P14324,P37268,Q16850,Q8NBQ5,Q14739
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
420,401,40,369,478,16,240,542,23
1148,2669,1312,478,16,1888,1567,1322,2861,1982,2835,23,420,2434,40,240,616,542,2661,2210,369,1252,401
0.3191957867311709,-0.5489222320312916,0.22373886117967634,0.9415089211120462,3.6430829250925005,-0.09290258413901609,0.10313738534059588,0.22373886117967634,-0.6795594013194657,-0.1425256923482076,-0.6532860190318247,3.2261902371399644,1.0528500237537732,-0.394503221669089,2.89017070238623,1.4872256449003394,0.7836669...
3,643
Membrane lipid biosynthetic process
10
25
2.931531
0.003373
Q96G23,Q06136,O43292,P27544,O15269,Q5H8A4,Q6Y1H2,O95470,O15121,Q13510
Processes and pathways
GO Biological process
msigdb_gobp
131,69,360,553,388,176,408,718,116,158
116,388,1634,360,2119,718,859,2300,553,69,158,1811,176,408,1286,1334,1240,2052,131,1340,778,1625,1670,1433,2875
2.007640931103598,1.097068061484193,0.054488318052800216,1.1630605789708375,-0.21743476674892134,0.6694704024024033,0.5307763897453316,-0.3182189232285267,0.8515992373556479,2.4078652087559544,1.8022971674617145,-0.04352823551645443,1.698238787966205,1.074981518864855,0.247687286863095,0.22373886117967634,0.27157933021...
3,643
Membrane trafficking
76
269
2.92869
0.003404
Q9H0B6,P24390,Q92845,Q9NV70,O75976,Q9UPT5,P62258,Q15363,Q12965,Q96A65,Q13439,Q9Y6G9,Q96D71,O75935,Q14677,P05067,P86790,Q9H9E3,Q15276,Q5VZE5,Q86VN1,P35579,Q9BXS5,Q14108,O43237,Q8TBA6,O14653,P15586,P49755,Q96PC5,Q9UP83,P83436,Q13561,Q14203,P55327,Q9UNF0,P59998,P49257,O00291,Q01082,P50570,Q14789,O60763,Q9P2W9,Q6NUQ1,Q9278...
Processes and pathways
Reactome Pathways
msigdb_reactome
256,1,525,651,127,135,136,137,638,139,391,671,278,273,406,156,534,564,166,169,685,298,435,47,672,178,550,305,427,442,711,575,576,189,65,329,701,194,696,206,322,323,330,210,731,474,472,734,201,347,213,345,726,87,715,463,341,464,622,721,724,500,372,628,224,619,105,499,605,238,502,374,746,653,119,646
1750,2115,1589,3006,2775,2067,696,1405,87,947,972,2851,550,1678,605,2170,1633,3416,1361,1840,672,2023,715,2118,1962,1041,201,330,921,2073,273,127,1843,1792,2668,1496,224,1966,2178,119,858,3640,1044,2547,156,1795,2881,1190,2593,2778,305,3346,1929,1762,950,2463,2979,3361,1,768,2338,2635,1716,213,2302,238,298,1502,3263,89...
-0.01893323196983534,-0.21743476674892134,0.07884243567085535,-0.8120509037528868,-0.62708619656327,-0.1924012006648247,0.6924087361167105,0.17567132034205288,2.2294317463628888,0.46073067332952794,0.43727634598424736,-0.6795594013194657,0.8515992373556479,0.03007461598016483,0.7836669490667206,-0.2425328384980788,0.05...
3,643
Intermediate filament protein, conserved site [IPR018039]
7
8
2.912415
0.003586
Q16352,P02545,P07196,P08670,P20700,P07197,Q03252
Sequence
InterPro Conserved site
interpro_conserved_site
254,42,113,19,57,26,29
42,113,26,19,57,314,29,254
2.871236707602699,2.027977430849258,3.1522873279909853,3.445373456333539,2.583693325050595,1.2721729993532975,3.115174064703662,1.423144094018777
3,643
Intermediate filament, rod domain [IPR039008]
7
8
2.912415
0.003586
Q16352,P02545,P07196,P08670,P20700,P07197,Q03252
Sequence
InterPro Domain
interpro_domain
254,42,113,19,57,26,29
42,113,26,19,57,314,29,254
2.871236707602699,2.027977430849258,3.1522873279909853,3.445373456333539,2.583693325050595,1.2721729993532975,3.115174064703662,1.423144094018777
3,643
Cartilage development
13
17
2.907613
0.003642
Q9C0E8,Q96HY6,Q15043,P16435,O75844,P08133,P50454,P04818,Q16539,P27361,Q92830,Q9NX62,O95747
Processes and pathways
GO Biological process
msigdb_gobp
780,487,134,570,351,888,637,74,729,297,545,247,568
351,568,74,1683,888,570,297,1501,637,2750,134,729,545,963,487,780,247
1.184969903794314,0.8290032464607571,2.368442378517289,0.03007461598016483,0.507480352534478,0.8290032464607571,1.3155174609171851,0.1273735787791028,0.7609260502934108,-0.6009593444413444,1.9259388040531895,0.6694704024024033,0.8741475129403571,0.46073067332952794,0.9415089211120462,0.6234430164808086,1.46590580223513...
3,643
Neck muscle weakness
7
18
2.904826
0.003675
P02545,P07602,P06753,Q8WZ42,P11047,Q99720,P35637
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
42,76,296,179,218,27,284
42,296,76,218,284,2135,3191,1377,1856,1059,432,3083,179,27,1173,1141,2018,2329
2.871236707602699,1.3155174609171851,2.3090642821729386,1.5509437761405507,1.358693095009029,-0.21743476674892134,-1.0008034862861284,0.19973366863516875,-0.06818453902065648,0.39020697451391223,1.030673311900084,-0.86558396744226,1.698238787966205,3.133744274878295,0.3191957867311709,0.34292094779173377,-0.14252569234...
3,643
Vacuolar lumen
22
63
2.904655
0.003677
P17900,P07900,P53990,P28482,Q13510,P50897,O14773,Q9H7Z7,Q14108,O43681,P61916,P15586,P38435,Q9UM22,Q8IV08,P07602,P54802,Q8NHP8,P10253,P04066,Q9UMR5,P07355
Localization
GO Cellular component
msigdb_gocc
515,512,147,659,158,31,162,303,47,673,429,305,555,55,183,76,216,227,231,609,108,494
2332,1877,1558,162,673,2669,859,609,2880,2121,494,1758,76,3066,512,806,231,2944,743,1190,1759,1191,305,1442,515,2421,659,3336,555,3635,1935,31,1642,1977,147,216,2387,2136,429,2087,681,2476,1569,1278,158,47,1806,183,1819,227,2318,1242,1996,2445,3541,2730,796,303,2907,1141,55,108,1353
-0.34357988327025807,-0.09290258413901609,0.10313738534059588,1.7607870381690778,0.7152972491503666,-0.5489222320312916,0.5307763897453316,0.7836669490667206,-0.7059069408091564,-0.21743476674892134,0.9191020703510948,-0.01893323196983534,2.3090642821729386,-0.86558396744226,0.8966483619769324,0.5772125455062541,1.5085...
3,643
Variable expressivity
21
86
2.893491
0.00381
Q9UEY8,Q9Y4W6,O43707,P17900,Q13510,P35240,O00429,P02545,P06753,Q8WZ42,Q70HW3,P07602,P11166,Q8TD16,Q9H061,P03886,Q15427,Q13813,P07196,O00217,O15121
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
400,529,260,515,158,157,160,42,296,179,441,76,203,345,88,90,225,105,113,359,116
359,160,116,260,2119,1559,1441,3417,718,531,1149,42,90,2547,296,113,76,1684,2079,2219,203,515,832,1931,157,2384,2597,3042,2674,2184,1599,1320,1975,635,1641,1122,2229,2387,2747,770,3191,1892,1081,1377,2035,2834,2951,158,105,1985,2037,1413,1230,225,1731,1811,959,2839,3019,1905,1233,441,1533,345,1578,179,1099,2403,3600,87...
1.1630605789708375,1.781560842290383,2.007640931103598,1.401701779928311,-0.21743476674892134,0.10313738534059588,0.1515514229907377,-1.3622032056549125,0.6694704024024033,0.8741475129403571,0.3191957867311709,2.871236707602699,2.1492621159839103,-0.47139954319819993,1.3155174609171851,2.027977430849258,2.3090642821729...
3,643
Sterol biosynthesis
7
18
2.892961
0.003816
Q15392,Q9UKR5,Q15800,Q9UBM7,P37268,Q16850,Q14739
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
420,401,40,369,16,240,23
1148,2669,1312,478,16,1567,1322,2861,1982,2835,23,420,2434,40,240,369,1252,401
0.3191957867311709,-0.5489222320312916,0.22373886117967634,0.9415089211120462,3.6430829250925005,0.10313738534059588,0.22373886117967634,-0.6795594013194657,-0.1425256923482076,-0.6532860190318247,3.2261902371399644,1.0528500237537732,-0.394503221669089,2.89017070238623,1.4872256449003394,1.1630605789708375,0.271579330...
3,643
M phase
63
214
2.870653
0.004096
P62258,P57740,Q9Y6G9,O95067,P07900,P61019,P53990,Q8NFH4,Q8WVM7,O75935,Q14739,Q9UNM6,P28482,O95684,O00231,P61289,Q14980,P51665,Q16763,Q9BTX1,Q9H900,Q9UJX2,Q9BVL2,P02545,P27361,O43237,O95613,P50402,Q9UQE7,Q15008,Q9BS16,P20700,Q01105,Q14203,Q13561,Q9UPN4,O43242,O95347,P48556,Q9NTJ3,Q8N3U4,O43805,O60763,Q86XL3,O94927,Q7Z3B...
Processes and pathways
Reactome Pathways
msigdb_reactome
136,770,671,263,512,771,147,277,544,273,23,800,659,274,271,787,419,661,422,294,563,694,560,42,297,672,676,428,185,577,444,57,58,189,576,191,309,567,700,327,324,447,330,733,331,470,735,589,719,91,93,221,343,722,340,492,604,503,614,500,493,496,252
2115,271,2586,604,1438,1961,1753,672,309,2023,2740,3360,447,2940,2173,330,2024,3392,2501,3480,273,331,263,2668,567,676,274,42,2547,340,1683,493,1758,512,91,1884,2298,2126,496,2946,1121,2594,57,832,2507,1010,2183,3097,297,2382,589,1687,2823,659,952,719,1222,1597,3099,2826,2782,93,1050,1319,2385,1599,2132,2510,700,3486,1...
-0.21743476674892134,1.3802181900709822,-0.4971701187929715,0.7836669490667206,0.1515514229907377,-0.1425256923482076,-0.01893323196983534,0.7152972491503666,1.2721729993532975,-0.16743166552350902,-0.6009593444413444,-1.249427613926466,0.9861831680424349,-0.7588269213757284,-0.2425328384980788,1.2286577968396193,-0.16...
3,643
Retrograde transport endosome to golgi
11
39
2.860835
0.004225
Q9UNH7,O95249,P49257,Q8IUD2,O60271,Q8N1B4,Q96QK1,O60749,O75503,Q9P2D3,Q14203
Processes and pathways
GO Biological process
msigdb_gobp
629,224,194,43,477,472,241,201,181,583,189
1361,1840,477,2703,201,1363,181,224,1315,950,3263,194,3014,1693,1123,1081,1082,1896,189,1576,1452,43,619,472,1821,2278,1537,241,2060,2000,1870,583,1918,2908,1838,2772,629,1067,1875
0.19973366863516875,-0.06818453902065648,0.9415089211120462,-0.5749048809587229,1.6143043553854377,0.19973366863516875,1.6773130953634898,1.5297444135769949,0.22373886117967634,0.46073067332952794,-1.0829137074111654,1.6353460842060628,-0.8120509037528868,0.03007461598016483,0.34292094779173377,0.3665912224666737,0.366...
3,643
Dementia
21
64
2.859577
0.004242
O76024,O60313,P17900,P22626,Q13510,P05067,P35637,O00429,Q14108,P27544,O43681,P61916,O15118,P20700,Q14203,O60220,P07602,Q9Y487,P03886,Q96QK1,Q9NQZ5
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
633,261,515,658,158,156,284,160,47,553,673,429,50,57,189,436,76,79,90,241,257
160,50,673,436,261,1491,633,2591,1149,90,859,3504,2547,156,2121,76,1883,3095,515,57,2464,658,1500,553,3170,2856,284,2128,2597,2185,1320,2600,1051,2387,429,1193,704,1326,2306,2751,158,47,189,1577,2611,1059,1531,3370,1096,794,3054,241,1702,1244,3498,1864,257,1479,1141,823,1672,1675,1485,79
1.781560842290383,2.6802893561721626,0.7152972491503666,1.0084511164761645,1.401701779928311,0.1273735787791028,0.7609260502934108,-0.4971701187929715,0.3191957867311709,2.1492621159839103,0.5307763897453316,-1.5922363275505007,-0.47139954319819993,1.8022971674617145,-0.21743476674892134,2.3090642821729386,-0.092902584...
3,643
Pace of progression
35
182
2.85595
0.004291
Q9H0B6,Q05682,O95831,Q15043,O60313,O43707,Q00059,Q96D71,Q13510,Q99720,Q03252,O00429,Q9P0J0,O14773,Q9H078,P02545,Q86U42,Q14108,P15586,Q8WZ42,Q8IV08,P20700,Q14203,P50570,Q9UBS4,P54802,Q12768,Q8N1F7,P55263,P51530,P07196,O15121,Q14671,Q9NQZ5,Q9Y6M9
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
256,381,380,134,261,260,145,278,158,27,29,160,34,162,302,42,432,47,305,179,183,57,189,322,211,216,342,343,101,364,113,116,372,257,258
1256,160,2070,1877,550,162,1360,826,605,116,260,261,2118,2119,3036,2175,3210,804,3168,2589,1117,1441,2259,718,380,3590,42,859,2547,2181,1263,113,1313,1560,2378,2882,2335,2459,2418,305,1761,3212,57,2854,1500,2634,553,2030,1048,3394,2856,1931,1223,1502,1597,2551,1076,1407,954,635,1641,428,322,364,2600,2134,216,1051,2387,...
0.247687286863095,1.781560842290383,-0.1924012006648247,-0.09290258413901609,0.8515992373556479,1.7607870381690778,0.19973366863516875,0.5540203428545035,0.7836669490667206,2.007640931103598,1.401701779928311,1.401701779928311,-0.21743476674892134,-0.21743476674892134,-0.838778477489919,-0.2425328384980788,-1.028090602...
3,643
Smooth muscle contraction
6
13
2.855218
0.004301
Q05682,P09493,P18206,P06753,P67936,Q13177
Processes and pathways
Reactome Pathways
msigdb_reactome
381,2,164,296,15,287
1069,296,494,888,2,164,1565,2430,15,381,287,2609,1486
0.3665912224666737,1.3155174609171851,0.9191020703510948,0.507480352534478,4.771723202663586,1.7607870381690778,0.10313738534059588,-0.394503221669089,3.6964892125824678,1.1191099133204574,1.358693095009029,-0.4971701187929715,0.1515514229907377
3,643
Toe walking
8
25
2.854158
0.004315
O95831,Q01082,P02545,P07602,P06753,Q8TD16,Q99720,P35637
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
380,206,42,76,296,345,27,284
673,380,42,296,76,284,573,428,2135,1051,2387,1803,206,1228,1280,1199,2869,2243,3083,345,1779,27,1173,1141,2329
0.7152972491503666,1.1191099133204574,2.871236707602699,1.3155174609171851,2.3090642821729386,1.358693095009029,0.8290032464607571,1.030673311900084,-0.21743476674892134,0.39020697451391223,-0.3690078123018647,-0.04352823551645443,1.6143043553854377,0.2715793302199121,0.247687286863095,0.2954153714992455,-0.67955940131...
3,643
F-type and V-type ATPases
7
16
2.848829
0.004388
P56385,P18859,P06576,Q9Y487,Q9Y5K8,P24539,Q93050
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
482,75,109,79,180,219,30
1311,109,75,2264,2706,219,1316,572,2597,2429,482,1324,30,1550,79,180
0.22373886117967634,2.0482786735043907,2.348682347368294,-0.292924427202373,-0.5749048809587229,1.5509437761405507,0.22373886117967634,0.8290032464607571,-0.4971701187929715,-0.394503221669089,0.9415089211120462,0.22373886117967634,3.096576582716819,0.1273735787791028,2.3090642821729386,1.698238787966205
3,643
Intermediate filament cytoskeleton
11
36
2.846285
0.004423
Q16352,Q3SXM5,Q9UPN3,P02545,Q9UNZ2,P07196,P08670,P20700,P07197,P48681,Q03252
Localization
GO Cellular component
msigdb_gocc
254,357,402,42,174,113,19,57,26,314,29
2625,3403,3480,42,113,26,19,2821,2460,57,314,1272,1012,1642,3511,613,431,29,3144,538,254,1415,357,2436,2869,1779,1102,2804,2732,2107,1710,2969,2011,2811,174,402
-0.5230108310595,-1.3338731713342733,-1.5341498793287338,2.871236707602699,2.027977430849258,3.1522873279909853,3.445373456333539,-0.6532860190318247,-0.4200666292018141,2.583693325050595,1.2721729993532975,0.247687286863095,0.41376856372481113,0.054488318052800216,-1.6214283384487764,0.7836669490667206,1.0306733119000...
3,643
Axon development
25
86
2.837695
0.004544
Q96G23,Q9UPN3,Q9Y4W6,P16949,Q13439,P07900,A0MZ66,P53990,Q13177,P05067,O75955,Q9NQC3,P18206,P42892,P35613,P50570,P11047,P78344,P07196,O00264,P33176,O75962,Q8N0X7,P35221,P08238
Processes and pathways
GO Biological process
msigdb_gobp
131,402,529,12,391,512,387,147,287,156,530,425,164,59,64,322,218,365,113,112,238,118,506,497,495
387,2068,112,2625,1185,1714,530,118,1494,531,156,3430,113,512,495,2629,218,12,164,2222,3335,2549,2466,2635,238,497,64,1598,59,1599,2857,2676,322,147,3071,3279,2305,365,1980,2432,2346,2749,1512,2832,1852,2750,3075,287,391,2952,2561,3398,1771,2395,1898,2609,3435,2090,3220,707,1200,1201,506,2049,2993,2798,2148,131,875,129...
1.097068061484193,-0.1924012006648247,2.027977430849258,-0.5230108310595,0.2954153714992455,0.005600908079439391,0.8741475129403571,2.007640931103598,0.1273735787791028,0.8741475129403571,1.8022971674617145,-1.3906254114630787,2.027977430849258,0.8966483619769324,0.9191020703510948,-0.5230108310595,1.5509437761405507,3...
3,643
Spectrin/alpha-actinin [IPR018159]
9
13
2.837414
0.004548
Q9UPN3,Q01082,Q13813,P46939,Q03001,O43707,P12814,O75962,Q15149
Sequence
InterPro Repeat
interpro_repeat
402,206,105,518,431,260,332,118,538
605,260,118,332,2460,518,206,431,105,538,3083,1779,402
0.7836669490667206,1.401701779928311,2.007640931103598,1.2286577968396193,-0.4200666292018141,0.8966483619769324,1.6143043553854377,1.030673311900084,2.0685448343680264,0.8741475129403571,-0.86558396744226,-0.01893323196983534,1.097068061484193
3,643
Spectrin repeat [IPR002017]
8
11
2.806721
0.005005
Q9UPN3,Q01082,Q13813,P46939,Q03001,O43707,P12814,O75962
Sequence
InterPro Repeat
interpro_repeat
402,206,105,518,431,260,332,118
605,260,118,332,518,206,431,105,3083,1779,402
0.7836669490667206,1.401701779928311,2.007640931103598,1.2286577968396193,0.8966483619769324,1.6143043553854377,1.030673311900084,2.0685448343680264,-0.86558396744226,-0.01893323196983534,1.097068061484193
3,643
Anion transmembrane transport
15
45
2.798774
0.00513
O60831,P45880,Q9Y6M7,P53985,Q9H2D1,O15439,Q8TB61,P21796,Q13546,Q9UBX3,P08183,P51790,Q9UHG3,P30825,Q15041
Processes and pathways
GO Biological process
msigdb_gobp
291,352,631,481,11,259,173,77,595,86,275,679,56,371,125
259,1183,291,2025,922,2503,698,2670,3430,275,1118,2335,2632,77,371,352,679,1079,2135,481,1052,2645,2390,595,1084,125,1414,2838,173,2051,1031,1426,11,2965,1544,1344,2406,86,56,2013,2623,3229,1586,2167,631
1.401701779928311,0.2954153714992455,1.3371262631895455,-0.16743166552350902,0.48413189400814893,-0.445698559329321,0.6924087361167105,-0.5489222320312916,-1.3906254114630787,1.3802181900709822,0.34292094779173377,-0.34357988327025807,-0.5230108310595,2.3090642821729386,1.1411073335741186,1.184969903794314,0.7152972491...
3,643
DnaJ domain [IPR001623]
8
18
2.797891
0.005144
Q9Y2G8,Q9UBS4,O75937,O60884,Q99543,Q5F1R6,Q96KC8,Q8WXX5
Sequence
InterPro Domain
interpro_domain
881,211,117,742,580,706,123,709
1678,742,1491,117,1596,1886,1278,706,1655,709,905,123,580,2057,1787,211,1481,881
0.03007461598016483,0.6464819347119302,0.1273735787791028,2.007640931103598,0.07884243567085535,-0.09290258413901609,0.247687286863095,0.6924087361167105,0.054488318052800216,0.6924087361167105,0.507480352534478,1.9872689975161881,0.8290032464607571,-0.16743166552350902,-0.01893323196983534,1.6143043553854377,0.1515514...
3,643
Chaperone J-domain superfamily [IPR036869]
8
18
2.797891
0.005144
Q9Y2G8,Q9UBS4,O75937,O60884,Q99543,Q5F1R6,Q96KC8,Q8WXX5
Sequence
InterPro Superfamily
interpro_homologous_superfamily
881,211,117,742,580,706,123,709
1678,742,1491,117,1596,1886,1278,706,1655,709,905,123,580,2057,1787,211,1481,881
0.03007461598016483,0.6464819347119302,0.1273735787791028,2.007640931103598,0.07884243567085535,-0.09290258413901609,0.247687286863095,0.6924087361167105,0.054488318052800216,0.6924087361167105,0.507480352534478,1.9872689975161881,0.8290032464607571,-0.16743166552350902,-0.01893323196983534,1.6143043553854377,0.1515514...
3,643
Iron uptake and transport
6
18
2.797578
0.005149
Q13616,P30519,Q9Y487,Q9Y5K8,Q93050,P09601
Processes and pathways
Reactome Pathways
msigdb_reactome
300,13,79,180,30,63
3555,1044,63,2264,2706,2080,13,2128,2597,1324,2431,300,366,1383,30,1550,79,180
-1.7987265678678774,0.39020697451391223,2.4863261827117857,-0.292924427202373,-0.5749048809587229,-0.1924012006648247,3.749679860737421,-0.21743476674892134,-0.4971701187929715,0.22373886117967634,-0.394503221669089,1.3155174609171851,1.1630605789708375,0.19973366863516875,3.096576582716819,0.1273735787791028,2.3090642...
3,643
Ventricular arrhythmia
10
42
2.795949
0.005175
P09493,P10253,Q03001,P02545,P0DP25,P50402,Q8WZ42,P03886,P42892,O43772
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
2,231,431,42,110,428,179,90,59,61
61,2118,2373,829,2259,1149,42,90,2218,1497,2,110,231,2335,1191,2821,2460,2222,2464,461,554,1503,2674,59,2675,721,3117,428,431,1280,3120,1059,1991,3083,2486,1779,179,1099,757,1244,1173,3182
2.4863261827117857,-0.21743476674892134,-0.3690078123018647,0.5540203428545035,-0.292924427202373,0.3191957867311709,2.871236707602699,2.1492621159839103,-0.26769589647874387,0.1273735787791028,4.771723202663586,2.0482786735043907,1.5085051089288772,-0.34357988327025807,0.2954153714992455,-0.6532860190318247,-0.4200666...
3,643
Outer membrane
22
94
2.791801
0.005242
Q9NS69,Q16891,O60313,Q99720,O75431,O00429,Q8WWV3,P50402,P09601,P21796,O43169,Q8N4H5,Q9HCL2,P45880,Q8WY22,Q9UBM7,P42345,Q96B49,Q99623,O00264,Q9NX63,Q9NQZ5
Localization
GO Cellular component
msigdb_gocc
0,255,261,27,404,160,37,428,63,77,89,94,229,352,102,369,480,367,236,112,253,257
112,160,3637,89,261,2072,566,404,1842,1441,1637,2591,2669,3440,2629,63,1314,3212,77,2466,3098,2826,2636,480,925,352,428,2186,2471,1803,3319,2983,1228,749,538,1855,1451,255,1811,3146,3197,1330,1989,1990,3512,3289,840,792,2689,3127,506,94,3370,2359,3083,1384,37,1779,102,2799,367,2053,1702,876,2445,236,27,3109,3388,2527,2...
2.027977430849258,1.781560842290383,-3.914043062920226,2.1894147198285787,1.401701779928311,-0.1924012006648247,0.8290032464607571,1.074981518864855,-0.06818453902065648,0.1515514229907377,0.054488318052800216,-0.4971701187929715,-0.5489222320312916,-1.4191406568833251,-0.5230108310595,2.4863261827117857,0.223738861179...
3,643
Intermediate filament
11
20
2.783493
0.005378
Q16352,Q9UPN3,Q03001,P02545,P07196,P08670,P20700,P07197,P48681,Q03252,Q15149
Localization
GO Cellular component
msigdb_gocc
254,402,431,42,113,19,57,26,314,29,538
2625,42,113,26,19,2821,2460,57,314,1272,3511,613,431,29,538,254,2869,2804,2969,402
-0.5230108310595,2.871236707602699,2.027977430849258,3.1522873279909853,3.445373456333539,-0.6532860190318247,-0.4200666292018141,2.583693325050595,1.2721729993532975,0.247687286863095,-1.6214283384487764,0.7836669490667206,1.030673311900084,3.115174064703662,0.8741475129403571,1.423144094018777,-0.6795594013194657,-0....
3,643
Golgi stack
8
33
2.772472
0.005563
O95249,Q14789,Q15363,O60763,Q9UNZ2,P51572,Q8TBA6,O00461
Localization
GO Cellular component
msigdb_gocc
224,323,137,330,174,276,178,87
87,330,224,1682,1594,1507,276,1767,1695,1644,987,1570,1609,1227,521,1573,323,2395,137,1019,178,870,1578,1701,2762,2765,368,1475,3414,174,2162,3376,1038
2.2294317463628888,1.2286577968396193,1.5297444135769949,0.03007461598016483,0.07884243567085535,0.1273735787791028,1.3802181900709822,-0.01893323196983534,0.03007461598016483,0.054488318052800216,0.43727634598424736,0.10313738534059588,0.07884243567085535,0.2715793302199121,0.8966483619769324,0.10313738534059588,1.250...
3,643
Cholesterol metabolism with bloch and kandutschrussell pathways
7
24
2.765013
0.005692
Q15392,O95864,Q15800,Q9UBM7,P37268,Q16850,Q14739
Processes and pathways
WikiPathways
msigdb_wp
420,128,40,369,16,240,23
1145,2072,1148,1637,128,1312,478,3098,1224,16,1888,2083,1567,2861,1982,2835,641,23,420,2434,40,240,2932,369
0.3191957867311709,-0.1924012006648247,0.3191957867311709,0.054488318052800216,1.9464181144490575,0.22373886117967634,0.9415089211120462,-0.8924680307444701,0.2715793302199121,3.6430829250925005,-0.09290258413901609,-0.1924012006648247,0.10313738534059588,-0.6795594013194657,-0.1425256923482076,-0.6532860190318247,0.76...
3,643
Cholesterol biosynthesis
6
15
2.76191
0.005746
Q15392,Q15800,Q9UBM7,P37268,Q16850,Q14739
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
420,40,369,16,240,23
2669,1312,478,16,1567,1322,2861,1982,2835,23,420,2434,40,240,369
-0.5489222320312916,0.22373886117967634,0.9415089211120462,3.6430829250925005,0.10313738534059588,0.22373886117967634,-0.6795594013194657,-0.1425256923482076,-0.6532860190318247,3.2261902371399644,1.0528500237537732,-0.394503221669089,2.89017070238623,1.4872256449003394,1.1630605789708375
3,643
Abnormality of facial soft tissue
38
134
2.760922
0.005764
Q969G3,Q15043,O60313,O43707,Q8NFH4,Q13510,Q9UHX1,Q03252,P35240,Q15149,O00429,P02545,Q86U42,P06753,Q8WZ42,Q9Y448,P40855,Q14203,P16435,Q8N3U4,Q01082,P50570,Q96TA2,O75381,P28070,O60826,P11047,Q12768,Q8N1F7,O75844,P10253,Q9UBM7,P51530,Q96QK1,O15020,P07196,P25490,Q14738
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
130,134,261,260,277,158,548,29,157,538,160,42,432,296,179,445,313,189,570,324,206,322,208,202,589,459,218,342,343,351,231,369,364,241,605,113,612,614
2499,1114,160,1558,1360,605,3062,260,2454,2290,261,2072,459,1491,2175,202,351,2412,3260,42,859,296,113,231,218,2335,570,3212,2464,1930,612,589,2780,952,2635,1270,157,3140,2384,313,2227,2552,1011,1156,721,2267,322,364,2600,3379,1079,680,2134,1509,2135,863,2387,3265,770,3488,927,2643,1892,206,772,29,704,1377,2834,342,157...
-0.445698559329321,0.34292094779173377,1.781560842290383,0.10313738534059588,0.19973366863516875,0.7836669490667206,-0.86558396744226,1.401701779928311,-0.4200666292018141,-0.3182189232285267,1.401701779928311,-0.1924012006648247,0.9638691945115666,0.1273735787791028,-0.2425328384980788,1.6143043553854377,1.18496990379...
3,643
Export from cell
38
145
2.757146
0.005831
Q9UBV2,Q92614,Q9UPT5,P62258,Q32P28,Q96A65,O15439,P14174,Q8WU76,P08183,P50897,O00429,Q9BRK5,P35579,P49755,Q8WZ42,Q96PC5,Q68EM7,P09601,Q99584,P40939,O43760,Q92783,Q8N5M9,Q15019,P35580,P82094,P05771,Q9UNH7,P53985,Q9H4A5,O00233,P0DP25,Q96QK1,Q16850,Q96KC8,O95721,P15311
Processes and pathways
GO Biological process
msigdb_gobp
270,268,135,136,266,139,259,514,543,275,31,160,41,298,427,179,442,440,63,66,573,446,474,599,465,214,464,340,629,481,368,604,110,241,240,123,119,124
3006,2775,2068,604,160,1405,947,2332,948,803,259,1840,715,446,2072,2024,1714,1966,2503,119,1638,1312,1069,2218,1263,2413,340,1188,275,1684,63,110,2379,2027,1265,514,3449,124,744,1797,1046,1762,2463,2299,2300,2979,768,3068,1153,2745,3139,3395,298,214,1504,573,1599,1507,427,2676,2186,31,3014,1693,3487,1718,1123,481,2269,...
-0.8120509037528868,-0.62708619656327,-0.1924012006648247,0.7836669490667206,1.781560842290383,0.17567132034205288,0.46073067332952794,-0.34357988327025807,0.46073067332952794,0.5772125455062541,1.401701779928311,-0.06818453902065648,0.6694704024024033,0.9861831680424349,-0.1924012006648247,-0.16743166552350902,0.00560...
3,643
Aspiration pneumonia
11
28
2.755223
0.005865
Q969G3,Q8N3U4,Q8TAQ2,O95721,Q14683,P06753,Q9Y448,Q96EY7,P20700,Q13510,O60220
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
130,324,397,119,503,296,445,579,57,158,436
1000,436,119,859,296,2296,1442,57,2264,590,1599,862,1892,2951,158,503,2191,3322,1941,324,397,734,2277,130,579,1824,2368,445
0.41376856372481113,1.0084511164761645,1.9872689975161881,0.5307763897453316,1.3155174609171851,-0.3182189232285267,0.1515514229907377,2.583693325050595,-0.292924427202373,0.8063592485767881,0.07884243567085535,0.5307763897453316,-0.09290258413901609,-0.7588269213757284,1.8022971674617145,0.9191020703510948,-0.24253283...
3,643
Respiratory chain
10
34
2.754692
0.005875
Q9P0J0,O43676,P03886,P22695,Q9UDW1,Q6DKK2,O14949,Q16718,P14927,Q9Y6M9
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
34,3,90,81,18,318,115,316,92,258
359,3114,115,3,2973,3036,829,2588,1004,1591,1495,3577,2334,2077,1149,90,767,92,2548,3569,81,3394,1688,3408,1976,316,775,318,1332,873,3182,34,18,258
1.1630605789708375,-0.9194313337399534,2.007640931103598,4.573298093913296,-0.7854005981288927,-0.838778477489919,0.5540203428545035,-0.4971701187929715,0.41376856372481113,0.07884243567085535,0.1273735787791028,-1.8888027743308256,-0.34357988327025807,-0.1924012006648247,0.3191957867311709,2.1492621159839103,0.6234430...
3,643