term stringlengths 2 121 | overlap int64 6 281 | setsize int64 7 499 | score float64 1.96 10.6 | pval float64 0 0.05 | edge stringlengths 41 1.97k | type stringclasses 5
values | subtype stringclasses 24
values | subtype_key stringclasses 24
values | edge_idxs stringlengths 11 1.17k | ann_idxs stringlengths 19 2.31k | ann_vals stringlengths 124 9.94k | sig_size int64 2.2k 3.73k |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Triphalangeal thumb | 16 | 26 | 3.630997 | 0.000282 | P46777,P61254,Q07020,P62081,P62857,P62244,P62899,Q92889,P42766,Q9ULP9,P61353,P18077,Q9NVI1,P62847,P62854,P61313 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 125,80,531,434,436,435,47,95,15,50,592,341,219,25,64,31 | 747,341,2411,906,1752,15,125,2477,643,80,31,592,434,435,25,64,436,47,1091,531,2431,95,1804,1805,219,50 | 0.637316184085691,1.1111613487779155,-0.37700443540698164,0.5235857910422159,0.032894232644399175,3.528575244639867,1.8186080128566493,-0.426654247568139,0.7528747198305642,2.093521364597626,2.8984160204542766,0.8113589567569786,0.9897296751660267,0.9897296751660267,3.1303209321554855,2.234541210932711,0.98972967516602... | 3,643 |
Metabolism of amino acids and derivatives | 83 | 196 | 3.619777 | 0.000295 | P42766,Q15008,P62841,P62847,P61313,O43242,P84098,P08243,P23526,P25325,P62910,P49720,Q07020,P62333,P62899,P62854,P62753,P61513,P61254,O43324,P62269,P46776,P55036,P61353,P62266,P46777,Q96I15,O15382,P07814,Q9Y3U8,P60900,P25788,P62888,P60866,P28066,P25398,Q6YP21,P61927,P46778,P39023,P25787,P41252,Q02878,Q14997,P46779,Q9Y61... | Processes and pathways | Reactome Pathways | msigdb_reactome | 15,537,24,25,31,510,33,515,516,519,39,527,531,529,47,64,63,62,80,566,593,91,589,592,118,125,145,135,635,159,644,639,646,643,640,160,710,178,197,196,685,693,237,238,232,807,250,751,748,747,279,755,278,269,321,299,301,305,306,304,311,340,341,343,352,350,348,409,385,388,387,439,433,428,435,434,436,431,430,495,475,480,483 | 1263,1913,1914,884,1347,2461,135,1436,510,1058,566,2612,2689,340,3572,1176,2613,1067,3332,3248,2330,2083,635,2699,515,2701,747,2178,2085,2616,3012,3053,3310,748,2617,3013,1277,1278,269,1451,1073,1074,341,1554,751,825,299,3252,990,1366,516,3017,519,160,428,685,639,755,301,2270,343,640,2620,1076,1184,2622,1077,2706,3114,... | 0.3013745602323828,-0.07177053677304059,-0.07177053677304059,0.5235857910422159,0.2468749208094238,-0.426654247568139,1.7513670427695411,0.19278333017529875,0.8703239336226946,0.41162409949645146,0.8113589567569786,-0.5249504103946776,-0.5736061024396271,1.1111613487779155,-2.0610678175841555,0.356288737373063,-0.52495... | 3,643 |
Reticulocytopenia | 14 | 20 | 3.614264 | 0.000301 | P46777,P61254,Q07020,P62081,P62857,P62244,P62899,P61353,P42766,P18077,Q9Y3A5,P62847,P62854,P61313 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 125,80,531,434,436,435,47,592,15,341,562,25,64,31 | 747,341,1752,15,125,2477,643,80,31,592,434,435,25,64,436,47,1091,531,1805,562 | 0.637316184085691,1.1111613487779155,0.032894232644399175,3.528575244639867,1.8186080128566493,-0.426654247568139,0.7528747198305642,2.093521364597626,2.8984160204542766,0.8113589567569786,0.9897296751660267,0.9897296751660267,3.1303209321554855,2.234541210932711,0.9897296751660267,2.5236891441756804,0.4116240994964514... | 3,643 |
Mitotic cell cycle phase transition | 59 | 143 | 3.598896 | 0.00032 | Q68E01,P06400,O95067,P14635,Q00534,O43684,Q13257,P12270,Q9NZJ0,Q7LG56,O43670,P33981,Q13642,P49427,Q07864,P18074,P51948,P24941,Q96JB5,P78527,Q13616,Q86Y37,Q9P258,Q93034,Q9Y570,Q7Z460,O43683,O75122,P62753,Q7L2J0,P19447,P61289,Q13564,P61254,P11802,Q15910,Q9Y3I1,Q04637,Q6P1X5,P27695,Q9BVS4,P35241,P15927,O14965,Q9BTC8,O6088... | Processes and pathways | GO Biological process | msigdb_gobp | 259,5,6,124,252,249,651,637,291,141,379,520,534,272,768,270,274,518,720,165,533,712,330,857,464,851,296,420,63,71,427,433,199,80,194,845,221,595,358,76,216,578,823,810,501,567,487,244,337,465,588,839,807,478,483,805,260,399,545 | 1999,465,337,810,2002,2003,3410,379,296,249,3278,2257,567,892,2397,420,1736,6,1357,2082,3309,2545,2831,5,1069,1358,3602,3390,194,637,124,1182,823,270,1555,427,991,518,76,902,2091,2189,1185,520,578,906,3221,1934,272,1840,478,1462,3061,274,588,2420,2196,80,433,63,165,1383,483,252,1094,595,1941,1477,768,1481,3289,651,839,... | -0.12354184408581988,0.9297779869287993,1.1111613487779155,0.5802262548677871,-0.12354184408581988,-0.12354184408581988,-1.3548095072485222,1.050187786825878,1.1726596350338454,1.2972687676797499,-1.1335470777869139,-0.27667722707748915,0.8113589567569786,0.5235857910422159,-0.37700443540698164,0.9897296751660267,0.032... | 3,643 |
Adenocarcinoma of the intestines | 17 | 24 | 3.596235 | 0.000323 | P46777,P60866,Q13485,P61254,Q07020,P62081,P62857,P62244,P62899,P28340,P42766,P61353,P18077,P08708,P62847,P62854,P61313 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 125,643,254,80,531,434,436,435,47,687,15,592,341,747,25,64,31 | 747,341,687,1752,15,997,125,2477,643,80,31,592,434,435,25,64,436,47,1091,531,768,2353,254,1681 | 0.637316184085691,1.1111613487779155,0.6948631006681812,0.032894232644399175,3.528575244639867,0.4673874574355663,1.8186080128566493,-0.426654247568139,0.7528747198305642,2.093521364597626,2.8984160204542766,0.8113589567569786,0.9897296751660267,0.9897296751660267,3.1303209321554855,2.234541210932711,0.9897296751660267... | 3,643 |
Malignant genitourinary tract tumor | 14 | 21 | 3.568962 | 0.000358 | P46777,P52701,P61254,Q07020,P62081,P62857,P62244,P62899,P61353,P42766,P18077,P62847,P62854,P61313 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 125,163,80,531,434,436,435,47,592,15,341,25,64,31 | 747,341,1752,15,997,125,2477,163,2420,643,80,31,592,434,435,25,64,436,47,1091,531 | 0.637316184085691,1.1111613487779155,0.032894232644399175,3.528575244639867,0.4673874574355663,1.8186080128566493,-0.426654247568139,1.6186732764752128,-0.37700443540698164,0.7528747198305642,2.093521364597626,2.8984160204542766,0.8113589567569786,0.9897296751660267,0.9897296751660267,3.1303209321554855,2.2345412109327... | 3,643 |
Cytosolic small ribosomal subunit | 19 | 31 | 3.563756 | 0.000366 | Q9BY44,P62841,P62847,P15880,P62277,P25398,Q7Z478,P62854,P62753,P62701,P62244,P62081,P62857,P62241,P46782,P62269,P62263,P61247,P62266 | Localization | GO Cellular component | msigdb_gocc | 288,24,25,269,387,160,314,64,63,305,435,434,436,304,430,593,348,480,118 | 1550,747,2178,269,1366,160,1752,1190,430,2477,643,480,434,304,435,2351,348,118,593,387,1294,305,63,24,25,2032,64,436,1937,314,288 | 0.13909345271370782,0.637316184085691,-0.2259898614760554,1.234692175919743,0.2468749208094238,1.6186732764752128,0.032894232644399175,0.356288737373063,0.9897296751660267,-0.426654247568139,0.7528747198305642,0.9297779869287993,0.9897296751660267,1.1726596350338454,0.9897296751660267,-0.3270137385950589,1.111161348777... | 3,643 |
Normochromic anemia | 15 | 22 | 3.554843 | 0.000378 | P46777,P60866,P61254,Q07020,P62081,P62857,P04075,P62899,P62244,P42766,P61353,P18077,P62847,P62854,P61313 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 125,643,80,531,434,436,745,47,435,15,592,341,25,64,31 | 976,745,747,341,2619,1752,15,125,2477,1657,643,80,31,592,434,435,25,64,436,47,1091,531 | 0.4673874574355663,0.637316184085691,0.637316184085691,1.1111613487779155,-0.5249504103946776,0.032894232644399175,3.528575244639867,1.8186080128566493,-0.426654247568139,0.08579910129584352,0.7528747198305642,2.093521364597626,2.8984160204542766,0.8113589567569786,0.9897296751660267,0.9897296751660267,3.13032093215548... | 3,643 |
Polysomal ribosome | 15 | 26 | 3.540339 | 0.0004 | P84098,P83881,P62910,P83731,Q02878,Q9Y3U8,P62857,P62899,Q7Z417,Q02543,P62266,P63173,P62917,P62424,P62854 | Localization | GO Cellular component | msigdb_gocc | 33,439,39,483,237,159,436,47,359,350,118,388,279,278,64 | 970,1928,118,278,64,436,646,47,1198,39,1091,279,388,1937,483,439,33,350,237,531,2636,779,359,2502,1877,159 | 0.4673874574355663,-0.07177053677304059,1.8864444012100539,1.234692175919743,2.234541210932711,0.9897296751660267,0.7528747198305642,2.5236891441756804,0.356288737373063,2.6718102012330496,0.41162409949645146,1.234692175919743,1.050187786825878,-0.07177053677304059,0.9297779869287993,0.9897296751660267,2.89841602045427... | 3,643 |
Antigen processing ubiquitination proteasome degradation | 44 | 105 | 3.538814 | 0.000402 | Q9C0C9,Q15386,P19474,Q96J02,Q14999,Q15008,Q13867,P25789,P49427,P60900,P25788,O43242,Q14139,P28066,Q96ME1,Q8TDB6,P49720,Q63HN8,P62333,Q13616,Q93034,Q15345,Q7Z6Z7,Q12834,Q9ULT8,P20618,Q9GZZ9,P61289,P25786,O43164,P25787,Q9Y3I1,Q92530,O95352,Q5GLZ8,Q9Y4B6,P55036,Q14997,O75832,Q13309,P51665,Q8TBC4,Q13200,Q96PU5 | Processes and pathways | Reactome Pathways | msigdb_reactome | 797,256,11,146,18,537,535,755,272,644,639,510,34,640,721,40,527,45,529,533,857,441,315,180,734,299,614,433,428,679,685,221,495,570,357,114,589,238,340,839,833,661,352,401 | 1261,1263,1913,1914,884,1347,679,510,340,2400,2690,570,1066,1274,1074,11,299,1075,428,685,639,755,640,2620,1076,1184,1834,2091,1561,2190,2628,272,527,1193,833,1291,589,3021,2278,644,1006,2713,2200,433,914,1659,529,2777,1938,1200,1941,180,1481,352,839,533,1099,1485,535,34,3318,1577,238,18,537,441,1397,1106,256,1493,357,... | 0.3013745602323828,0.3013745602323828,-0.07177053677304059,-0.07177053677304059,0.5235857910422159,0.2468749208094238,0.6948631006681812,0.8703239336226946,1.1111613487779155,-0.37700443540698164,-0.5736061024396271,0.8113589567569786,0.41162409949645146,0.3013745602323828,0.41162409949645146,3.8577220570211566,1.17265... | 3,643 |
S phase | 52 | 104 | 3.536097 | 0.000406 | Q7Z5K2,P06400,Q15008,P25789,P60900,P25788,O43242,O43913,Q07864,P25205,P51948,P49841,P24941,P28066,P33991,P49720,Q99436,P62333,Q14181,Q13616,O00487,Q9UBD5,P35244,P62191,Q29RF7,P20618,Q9NTI5,P61289,P25786,P25787,P11802,P28340,P15927,Q92530,P33992,Q9NR33,P55036,Q9H1A4,Q14997,P18858,Q13309,P51530,P49736,O75832,P35251,P5166... | Processes and pathways | Reactome Pathways | msigdb_reactome | 541,5,537,755,644,639,510,511,768,271,274,641,518,640,521,527,939,529,182,533,884,459,54,914,846,299,873,433,428,685,194,687,823,495,577,1044,589,1042,238,100,839,104,583,340,101,833,807,345,830,829,352,941 | 1263,1913,1914,884,1347,510,511,1731,3278,2688,340,5,982,194,1362,823,1074,100,299,518,271,428,685,639,755,1745,640,2620,1076,1184,687,2091,2092,521,577,1079,54,1930,2475,101,1561,345,2094,1286,2190,2628,1650,829,830,527,1193,583,641,104,833,274,589,1004,644,433,914,1659,529,2777,1941,768,2209,1481,352,839,3119,533,182... | 0.3013745602323828,-0.07177053677304059,-0.07177053677304059,0.5235857910422159,0.2468749208094238,0.8703239336226946,0.8703239336226946,0.032894232644399175,-1.1335470777869139,-0.5736061024396271,1.1111613487779155,4.54402937594712,0.4673874574355663,1.4883650140779006,0.2468749208094238,0.5802262548677871,0.41162409... | 3,643 |
Erythroid hypoplasia | 14 | 19 | 3.519811 | 0.000432 | P46777,P61254,Q07020,P62081,P62857,P62244,P62899,P61353,P42766,P18077,P62263,P62847,P62854,P61313 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 125,80,531,434,436,435,47,592,15,341,348,25,64,31 | 747,341,1752,15,125,2477,643,80,31,592,434,435,348,25,64,436,47,1091,531 | 0.637316184085691,1.1111613487779155,0.032894232644399175,3.528575244639867,1.8186080128566493,-0.426654247568139,0.7528747198305642,2.093521364597626,2.8984160204542766,0.8113589567569786,0.9897296751660267,0.9897296751660267,1.1111613487779155,3.1303209321554855,2.234541210932711,0.9897296751660267,2.5236891441756804... | 3,643 |
Abnormal mean corpuscular volume | 15 | 26 | 3.494088 | 0.000476 | P46777,P61254,Q07020,P62081,P62857,P62244,P62899,P61353,P42766,P18077,Q9Y3A5,Q5F1R6,P62847,P62854,P61313 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 125,80,531,434,436,435,47,592,15,341,562,93,25,64,31 | 747,341,1752,15,125,2477,643,913,80,31,592,434,435,25,64,436,47,1091,1571,531,93,1862,1124,1220,1338,562 | 0.637316184085691,1.1111613487779155,0.032894232644399175,3.528575244639867,1.8186080128566493,-0.426654247568139,0.7528747198305642,0.5235857910422159,2.093521364597626,2.8984160204542766,0.8113589567569786,0.9897296751660267,0.9897296751660267,3.1303209321554855,2.234541210932711,0.9897296751660267,2.5236891441756804... | 3,643 |
Dna damage response | 11 | 26 | 3.475098 | 0.000511 | P06400,Q00534,P14635,O95067,Q86UE8,P78527,P11802,Q13535,Q7LG56,P42574,P35251 | Processes and pathways | WikiPathways | msigdb_wp | 5,252,124,6,316,165,194,105,141,77,101 | 2254,337,2397,6,3309,5,1069,194,124,823,518,2189,101,906,77,581,1840,165,252,1094,105,1393,141,316,1694,1805 | -0.27667722707748915,1.1111613487779155,-0.37700443540698164,4.3689581005135825,-1.1783350652217268,4.54402937594712,0.41162409949645146,1.4883650140779006,1.8186080128566493,0.5802262548677871,0.8703239336226946,-0.2259898614760554,1.954875734282166,0.5235857910422159,2.093521364597626,0.8113589567569786,-0.0196270571... | 3,643 |
Class i mhc mediated antigen processing presentation | 49 | 128 | 3.474759 | 0.000511 | Q9C0C9,Q15386,P19474,Q96J02,O95487,Q14999,Q15008,Q13867,P25789,P49427,P60900,P25788,O43242,O95486,Q14139,P28066,Q96ME1,Q8TDB6,P49720,Q63HN8,P62333,Q13616,Q93034,Q15345,Q7Z6Z7,Q12834,Q9ULT8,P20618,Q9GZZ9,P61289,P25786,O43164,P25787,Q9Y3I1,Q92530,O95352,Q5GLZ8,Q9Y4B6,P55036,Q14997,O75832,P55735,Q13309,P51665,P09429,Q8TBC... | Processes and pathways | Reactome Pathways | msigdb_reactome | 797,256,11,146,744,18,537,535,755,272,644,639,510,268,34,640,721,40,527,45,529,533,857,441,315,180,734,299,614,433,428,679,685,221,495,570,357,114,589,238,340,835,839,833,471,661,352,808,401 | 1261,2390,1263,1913,1914,884,1347,2819,967,2950,679,510,3008,340,2400,2690,1354,570,1066,268,744,1274,981,471,2333,1074,11,299,1075,428,685,639,755,3285,2186,640,2620,1076,1184,1834,2340,2091,1561,2190,2628,272,527,1193,3222,833,1291,1379,589,835,3021,2029,2848,2278,644,1006,2713,2200,433,2965,914,1659,529,2777,1938,12... | 0.3013745602323828,-0.37700443540698164,0.3013745602323828,-0.07177053677304059,-0.07177053677304059,0.5235857910422159,0.2468749208094238,-0.6699553268222116,0.4673874574355663,-0.7650507386283446,0.6948631006681812,0.8703239336226946,-0.8121388295267228,1.1111613487779155,-0.37700443540698164,-0.5736061024396271,0.24... | 3,643 |
Cytosolic large ribosomal subunit | 29 | 47 | 3.443408 | 0.000574 | P46777,P36578,P40429,P42766,P63173,P62917,P62424,Q9Y3U8,P61313,P84098,Q9NP64,P62910,P62899,P83881,P61927,P61513,P26373,P62750,P46778,P61254,P39023,P50914,P46776,Q02878,P18077,P27635,P46779,Q02543,P83731 | Localization | GO Cellular component | msigdb_gocc | 125,250,385,15,388,279,278,159,31,33,37,39,47,439,178,62,301,306,197,80,196,431,91,237,341,343,232,350,483 | 2330,2083,341,1554,751,301,343,1077,1370,904,250,196,385,15,91,125,197,232,911,999,431,2710,80,31,592,62,178,278,306,1090,646,47,1198,39,1091,279,388,483,439,33,350,237,531,2861,3301,37,159 | -0.3270137385950589,-0.174946489808922,1.1111613487779155,0.13909345271370782,0.637316184085691,1.1726596350338454,1.1111613487779155,0.41162409949645146,0.2468749208094238,0.5235857910422159,1.2972687676797499,1.4883650140779006,1.050187786825878,3.528575244639867,2.0239015433854965,1.8186080128566493,1.48836501407790... | 3,643 |
Absent thumb | 16 | 27 | 3.434628 | 0.000593 | O94761,P46777,P61254,Q07020,P62081,P62857,P62244,P62899,Q92889,P42766,P61353,P18077,Q9NVI1,P62847,P62854,P61313 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 297,125,80,531,434,436,435,47,95,15,592,341,219,25,64,31 | 1913,297,747,341,2769,1752,15,125,2477,643,80,31,592,434,435,25,64,436,47,1091,531,3155,1485,2431,95,1805,219 | -0.07177053677304059,1.1726596350338454,0.637316184085691,1.1111613487779155,-0.6219395983652799,0.032894232644399175,3.528575244639867,1.8186080128566493,-0.426654247568139,0.7528747198305642,2.093521364597626,2.8984160204542766,0.8113589567569786,0.9897296751660267,0.9897296751660267,3.1303209321554855,2.234541210932... | 3,643 |
Nervous system development | 93 | 224 | 3.407819 | 0.000655 | P42766,Q15008,P62841,P62847,P61313,O43242,P84098,P62910,P49720,Q07020,P62333,P62899,P62854,Q96S59,Q13885,P61513,P62753,P61254,Q04637,P62495,P35241,P62269,P46776,O75116,P55036,P61353,P62266,Q14185,P46777,Q9Y490,Q9Y5S9,Q9Y3U8,P60900,P25788,P62888,P61586,P60866,P49841,P28066,P25398,Q9HAU5,P61927,P46778,Q00169,P39023,P2578... | Processes and pathways | Reactome Pathways | msigdb_reactome | 15,537,24,25,31,510,33,39,527,531,529,47,64,611,597,62,63,80,595,594,578,593,91,87,589,592,118,131,125,674,675,159,644,639,646,645,643,641,640,160,728,178,197,198,196,685,688,684,246,237,238,233,232,250,751,750,746,747,279,763,278,755,269,299,301,305,306,304,340,341,343,352,350,348,385,384,388,387,439,420,433,428,435,4... | 1821,1263,1913,1914,884,3274,3358,1347,1823,2391,2462,510,87,420,340,3571,2172,1442,977,821,2470,3010,1549,2330,2083,2831,746,1180,3283,3412,896,747,2178,3052,2408,3413,1552,684,3467,2336,1182,750,269,1640,3362,2337,1074,341,1554,751,824,987,299,1366,1367,3058,160,428,685,639,755,1368,301,993,343,640,2620,1076,1184,688... | -0.019627057122083305,0.3013745602323828,-0.07177053677304059,-0.07177053677304059,0.5235857910422159,-1.1335470777869139,-1.2671010666360616,0.2468749208094238,-0.019627057122083305,-0.37700443540698164,-0.426654247568139,0.8703239336226946,2.0239015433854965,0.9897296751660267,1.1111613487779155,-2.0610678175841555,-... | 3,643 |
Base excision repair | 12 | 22 | 3.407462 | 0.000656 | Q14191,Q9UGN5,P18858,P51530,P28340,P39748,P29372,P15927,P27695,Q7Z6Z7,P35244,Q07864 | Processes and pathways | GO Biological process | msigdb_gobp | 772,620,100,104,687,345,231,823,76,315,54,768 | 1362,1831,823,100,1641,1366,1745,76,687,231,54,345,831,104,768,772,315,1867,2053,1975,1335,620 | 0.2468749208094238,-0.019627057122083305,0.5802262548677871,1.954875734282166,0.08579910129584352,0.2468749208094238,0.032894232644399175,2.093521364597626,0.6948631006681812,1.3603994825359238,2.377931653766487,1.1111613487779155,0.5802262548677871,1.954875734282166,0.637316184085691,0.637316184085691,1.17265963503384... | 3,643 |
Abnormality of the thenar eminence | 13 | 18 | 3.406935 | 0.000657 | P46777,P62244,P61353,P18077,P62081,Q07020,P62857,P61254,P42766,P62899,P62847,P62854,P61313 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 125,435,592,341,434,531,436,80,15,47,25,64,31 | 747,341,1752,15,125,2477,643,80,31,592,434,435,25,64,436,47,1091,531 | 0.637316184085691,1.1111613487779155,0.032894232644399175,3.528575244639867,1.8186080128566493,-0.426654247568139,0.7528747198305642,2.093521364597626,2.8984160204542766,0.8113589567569786,0.9897296751660267,0.9897296751660267,3.1303209321554855,2.234541210932711,0.9897296751660267,2.5236891441756804,0.4116240994964514... | 3,643 |
Mirna regulation of dna damage response | 11 | 27 | 3.396416 | 0.000683 | P06400,Q00534,P14635,O95067,Q86UE8,P78527,P11802,Q13535,Q7LG56,P42574,P35251 | Processes and pathways | WikiPathways | msigdb_wp | 5,252,124,6,316,165,194,105,141,77,101 | 2254,337,2397,6,3309,5,1069,194,124,823,518,2189,1079,101,906,77,581,1840,165,252,1094,105,1393,141,316,1694,1805 | -0.27667722707748915,1.1111613487779155,-0.37700443540698164,4.3689581005135825,-1.1783350652217268,4.54402937594712,0.41162409949645146,1.4883650140779006,1.8186080128566493,0.5802262548677871,0.8703239336226946,-0.2259898614760554,0.41162409949645146,1.954875734282166,0.5235857910422159,2.093521364597626,0.8113589567... | 3,643 |
Regulation of mitotic cell cycle phase transition | 36 | 107 | 3.344944 | 0.000823 | Q68E01,P06400,P14635,O43684,Q13257,P12270,Q9NZJ0,Q7LG56,O43670,P33981,Q13642,P18074,P51948,P24941,P78527,Q9P258,O43683,Q7L2J0,P19447,P61289,Q13564,P61254,P11802,Q9Y3I1,Q04637,P27695,Q9BVS4,P35241,Q9BTC8,O60885,Q5JVF3,Q969U7,O14757,P53350,Q7Z7L1,Q92547 | Processes and pathways | GO Biological process | msigdb_gobp | 259,5,124,249,651,637,291,141,379,520,534,270,274,518,165,330,296,71,427,433,199,80,194,221,595,76,216,578,501,567,487,244,337,588,260,545 | 1999,337,810,2002,2003,3410,379,296,249,3278,2257,567,892,2397,1357,2082,3309,2545,5,1069,194,637,124,823,270,427,991,518,76,902,2091,2189,1185,520,578,906,1840,1462,3061,274,588,2420,2196,80,433,165,1383,595,1941,1481,3289,651,3119,199,1485,1205,534,1777,1852,1017,1398,845,1491,487,259,1498,3074,3075,2364,71,141,260,2... | -0.12354184408581988,1.1111613487779155,0.5802262548677871,-0.12354184408581988,-0.12354184408581988,-1.3548095072485222,1.050187786825878,1.1726596350338454,1.2972687676797499,-1.1335470777869139,-0.27667722707748915,0.8113589567569786,0.5235857910422159,-0.37700443540698164,0.2468749208094238,-0.174946489808922,-1.17... | 3,643 |
Pure red cell aplasia | 13 | 20 | 3.322703 | 0.000891 | P46777,P61254,Q07020,P62081,P62857,P62244,P62899,P61353,P42766,P18077,P62847,P62854,P61313 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 125,80,531,434,436,435,47,592,15,341,25,64,31 | 2081,3309,747,341,1752,15,125,2477,643,80,31,592,434,435,25,64,436,47,1091,531 | -0.174946489808922,-1.1783350652217268,0.637316184085691,1.1111613487779155,0.032894232644399175,3.528575244639867,1.8186080128566493,-0.426654247568139,0.7528747198305642,2.093521364597626,2.8984160204542766,0.8113589567569786,0.9897296751660267,0.9897296751660267,3.1303209321554855,2.234541210932711,0.989729675166026... | 3,643 |
Upper limb undergrowth | 8 | 22 | 3.27272 | 0.001065 | O94761,P61254,Q13535,Q14999,Q8NCM8,Q9NVI1,Q12830,Q92889 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 297,80,105,18,22,219,119,95 | 1913,967,3109,297,1926,906,3020,1752,80,2034,119,105,1300,18,2431,490,22,95,3030,1804,1805,219 | -0.07177053677304059,0.4673874574355663,-0.9054161621172195,1.1726596350338454,-0.07177053677304059,0.5235857910422159,-0.8121388295267228,0.032894232644399175,2.093521364597626,-0.12354184408581988,1.8864444012100539,1.954875734282166,0.3013745602323828,3.528575244639867,-0.37700443540698164,0.9297779869287993,3.20879... | 3,643 |
Regulation of cell cycle phase transition | 41 | 137 | 3.26745 | 0.001085 | Q68E01,P06400,P14635,O43684,Q13257,P12270,Q9NZJ0,Q7LG56,O43670,P33981,Q13642,P18074,P51948,P24941,P78527,Q9P258,Q9UNS1,O43683,Q7L2J0,P19447,Q08J23,Q13564,P61254,P61289,P11802,Q9Y3I1,Q04637,P27695,Q9BVS4,P35241,Q9BTC8,O60885,Q5JVF3,Q969U7,O14757,P53350,Q13535,P51530,Q7Z7L1,Q8N6R0,Q92547 | Processes and pathways | GO Biological process | msigdb_gobp | 259,5,124,249,651,637,291,141,379,520,534,270,274,518,165,330,333,296,71,427,307,199,80,433,194,221,595,76,216,578,501,567,487,244,337,588,105,104,260,261,545 | 1432,1999,337,810,2002,2003,3410,379,296,249,3278,2257,567,892,2397,3179,2688,2399,1357,2082,3309,2545,5,1069,1924,194,637,124,823,270,427,3498,991,518,76,902,2091,2189,1185,520,578,906,997,1840,1462,104,3061,274,588,2420,2196,80,433,165,1383,595,767,1941,307,2211,1481,3289,651,3119,105,199,1485,1205,534,771,2719,1777,... | 0.19278333017529875,-0.12354184408581988,1.1111613487779155,0.5802262548677871,-0.12354184408581988,-0.12354184408581988,-1.3548095072485222,1.050187786825878,1.1726596350338454,1.2972687676797499,-1.1335470777869139,-0.27667722707748915,0.8113589567569786,0.5235857910422159,-0.37700443540698164,-0.997521253539814,-0.5... | 3,643 |
Diamond-Blackfan anemia | 11 | 16 | 3.266223 | 0.00109 | P46777,P62244,P62081,P18077,Q07020,P62857,P61254,P42766,P62847,P62854,P61313 | Drugs and Diseases | Protein Atlas Disease involvement | protein_atlas_disease_involvement | 125,435,434,341,531,436,80,15,25,64,31 | 747,341,1752,15,125,2477,80,31,592,434,435,25,64,436,1091,531 | 0.637316184085691,1.1111613487779155,0.032894232644399175,3.528575244639867,1.8186080128566493,-0.426654247568139,2.093521364597626,2.8984160204542766,0.8113589567569786,0.9897296751660267,0.9897296751660267,3.1303209321554855,2.234541210932711,0.9897296751660267,0.41162409949645146,0.8703239336226946 | 3,643 |
Armadillo-like helical [IPR011989] | 52 | 126 | 3.223186 | 0.001268 | Q9C0E2,Q7Z5K2,Q9BTW9,Q9UI26,Q9Y678,Q9BTY7,Q86Y56,O60879,Q9Y263,Q5VYK3,O14981,P53618,Q86XI2,Q9BPX3,P78527,Q92616,P42345,Q96T76,Q8TCG1,Q9HAV4,Q7Z460,Q5JTH9,Q29RF7,Q9ULT8,O75122,O75165,Q9UBF2,Q9NTI5,Q14738,Q92845,O43747,P42695,Q96JJ3,Q6KC79,O95782,O95373,O14980,Q9Y5L0,Q9Y4B6,Q14671,Q14997,P50851,Q13535,O60610,O14617,Q1320... | Sequence | InterPro Superfamily | interpro_homologous_superfamily | 667,541,550,149,963,287,931,20,157,393,30,759,317,862,165,187,524,722,854,328,851,849,846,734,420,421,877,873,310,83,815,429,497,490,821,571,811,375,114,485,238,586,105,468,335,352,354,657,117,654,548,671 | 2894,1262,964,2075,2001,335,2818,811,30,1918,1825,815,1545,468,1061,3108,891,20,420,421,1269,976,2400,1442,571,821,2905,2188,1078,3018,524,429,1648,117,586,2909,1375,2274,759,1087,2100,165,3155,1574,352,105,354,1577,485,310,2357,238,654,2975,2573,1675,846,849,2495,393,2575,490,1306,2729,2789,851,1588,541,1126,657,317,9... | -0.717657624490921,0.3013745602323828,0.4673874574355663,-0.174946489808922,-0.12354184408581988,1.1111613487779155,-0.6699553268222116,0.5802262548677871,2.8984160204542766,-0.07177053677304059,-0.019627057122083305,0.5802262548677871,0.13909345271370782,0.9297779869287993,0.41162409949645146,-0.9054161621172195,0.523... | 3,643 |
Abnormal number of erythroid precursors | 14 | 25 | 3.217331 | 0.001294 | P46777,P61254,Q07020,P62081,P62857,P62244,P62899,P61353,P42766,P18077,P62263,P62847,P62854,P61313 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 125,80,531,434,436,435,47,592,15,341,348,25,64,31 | 976,2081,3309,2084,747,341,1752,15,125,2477,643,80,31,592,434,435,348,25,64,436,47,1091,531,1124,2759 | 0.4673874574355663,-0.174946489808922,-1.1783350652217268,-0.174946489808922,0.637316184085691,1.1111613487779155,0.032894232644399175,3.528575244639867,1.8186080128566493,-0.426654247568139,0.7528747198305642,2.093521364597626,2.8984160204542766,0.8113589567569786,0.9897296751660267,0.9897296751660267,1.11116134877791... | 3,643 |
Osteosarcoma | 17 | 26 | 3.193167 | 0.001407 | O94761,P46777,P60866,P06400,Q14191,P61254,Q07020,P62081,P62857,P62244,P62899,P61353,P42766,P18077,P62847,P62854,P61313 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 297,125,643,5,772,80,531,434,436,435,47,592,15,341,25,64,31 | 297,3333,3309,5,747,341,1752,15,125,2477,643,80,31,592,434,435,25,64,436,47,1091,531,1013,1772,772,1042 | 1.1726596350338454,-1.2228519251976793,-1.1783350652217268,4.54402937594712,0.637316184085691,1.1111613487779155,0.032894232644399175,3.528575244639867,1.8186080128566493,-0.426654247568139,0.7528747198305642,2.093521364597626,2.8984160204542766,0.8113589567569786,0.9897296751660267,0.9897296751660267,3.130320932155485... | 3,643 |
Partial duplication of the phalanx of hand | 13 | 21 | 3.19249 | 0.001411 | P46777,P61254,Q07020,P62081,P62857,P62244,P62899,P61353,P42766,P18077,P62847,P62854,P61313 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 125,80,531,434,436,435,47,592,15,341,25,64,31 | 747,341,1752,15,125,2477,2911,643,80,31,592,434,435,25,64,436,47,1091,531,3533,1805 | 0.637316184085691,1.1111613487779155,0.032894232644399175,3.528575244639867,1.8186080128566493,-0.426654247568139,-0.717657624490921,0.7528747198305642,2.093521364597626,2.8984160204542766,0.8113589567569786,0.9897296751660267,0.9897296751660267,3.1303209321554855,2.234541210932711,0.9897296751660267,2.5236891441756804... | 3,643 |
Duplication of thumb phalanx | 13 | 23 | 3.148069 | 0.001644 | P46777,P61254,Q07020,P62081,P62857,P62244,P62899,P61353,P42766,P18077,P62847,P62854,P61313 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 125,80,531,434,436,435,47,592,15,341,25,64,31 | 747,341,2552,1752,1372,15,125,2477,2911,643,80,31,592,434,435,25,64,436,47,1091,531,3533,1805 | 0.637316184085691,1.1111613487779155,-0.4759679989713774,0.032894232644399175,0.2468749208094238,3.528575244639867,1.8186080128566493,-0.426654247568139,-0.717657624490921,0.7528747198305642,2.093521364597626,2.8984160204542766,0.8113589567569786,0.9897296751660267,0.9897296751660267,3.1303209321554855,2.23454121093271... | 3,643 |
Regulation of ubiquitin protein transferase activity | 12 | 26 | 3.145258 | 0.001659 | P46777,O43684,Q8TDB6,P53350,Q13257,P62081,Q13526,P62841,Q12834,Q96GX5,P15880,P61927 | Processes and pathways | GO Biological process | msigdb_gobp | 125,249,40,588,651,434,140,24,180,399,269,178 | 738,249,2257,2079,269,125,588,643,2200,178,434,1090,24,1091,2777,1938,180,651,140,1493,40,399,2130,1883,2067,1428 | 0.637316184085691,1.2972687676797499,-0.27667722707748915,-0.174946489808922,1.234692175919743,1.8186080128566493,0.8113589567569786,0.7528747198305642,-0.2259898614760554,1.553221452559307,0.9897296751660267,0.41162409949645146,3.1303209321554855,0.41162409949645146,-0.6219395983652799,-0.07177053677304059,1.553221452... | 3,643 |
Abnormal hemoglobin | 15 | 25 | 3.126287 | 0.00177 | P46777,P61254,Q07020,P62081,P62857,P62244,P62899,P61353,P42766,P18077,Q9Y3A5,Q5F1R6,P62847,P62854,P61313 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 125,80,531,434,436,435,47,592,15,341,562,93,25,64,31 | 3306,2176,747,341,1752,15,3518,125,2477,643,913,80,31,592,434,435,25,64,436,47,1091,531,93,1510,562 | -1.1783350652217268,-0.2259898614760554,0.637316184085691,1.1111613487779155,0.032894232644399175,3.528575244639867,-1.6955736238491228,1.8186080128566493,-0.426654247568139,0.7528747198305642,0.5235857910422159,2.093521364597626,2.8984160204542766,0.8113589567569786,0.9897296751660267,0.9897296751660267,3.130320932155... | 3,643 |
Abnormal aortic morphology | 44 | 121 | 3.125259 | 0.001776 | P46777,Q13485,O43684,Q9Y5S9,Q9Y3Z3,O95155,P42766,O75792,O75369,P55263,P08708,P62847,P61313,Q06124,P60866,Q9UBS4,Q8WYQ5,Q07020,Q06787,P62899,Q93074,Q7Z6Z7,Q8N806,P62854,O43683,P61254,P62244,P62081,P62857,O15460,P28482,Q9NVI1,Q14839,Q92889,P31153,Q9BPU6,P61353,Q7Z5J4,P18077,P49711,O95394,Q12830,P49815,Q96PU5 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 125,254,249,675,413,743,15,742,632,386,747,25,31,767,643,38,856,531,530,47,858,315,604,64,296,80,435,434,436,192,688,219,703,95,344,246,592,782,341,103,469,119,117,401 | 2894,1913,192,296,249,2257,2822,632,1633,742,2825,743,469,3110,2470,3637,3333,3308,1829,747,341,2472,989,1365,2473,2014,688,2188,344,2475,1187,906,1752,15,1648,2627,125,2477,910,1374,103,117,1085,2347,1379,1292,1936,386,2910,643,80,31,592,2561,434,2350,435,25,64,436,47,1091,2282,1664,1386,2206,767,530,531,119,254,1577,... | -0.717657624490921,-0.07177053677304059,1.4883650140779006,1.1726596350338454,1.2972687676797499,-0.27667722707748915,-0.6699553268222116,0.7528747198305642,0.08579910129584352,0.637316184085691,-0.6699553268222116,0.637316184085691,0.9297779869287993,-0.9054161621172195,-0.426654247568139,-5.113821130050931,-1.2228519... | 3,643 |
Cell cycle checkpoints | 63 | 157 | 3.122024 | 0.001796 | O95067,P14635,Q14191,O43684,Q13257,Q9NWV8,Q15008,P25789,P60900,Q2NKX8,P25788,O43242,O43913,P25205,P24941,P28066,P33991,P49720,P62333,Q96EE3,Q9P258,O00487,O60921,Q9UBD5,Q7L590,Q7Z460,P35244,Q12834,P62191,O43683,O75122,P20618,P43034,P38398,P61289,P25786,Q14204,P63167,Q14738,P25787,P15927,Q92530,O14980,P33992,O14757,P5503... | Processes and pathways | Reactome Pathways | msigdb_reactome | 6,124,772,249,651,951,537,755,644,391,639,510,511,271,518,640,521,527,529,860,330,884,892,459,184,851,54,180,914,296,420,299,909,906,433,428,308,437,310,685,823,495,811,577,337,589,588,107,238,105,104,583,226,340,835,807,833,352,941,354,939,546,545 | 1170,1263,1913,1914,884,337,1347,811,226,510,2002,296,249,511,1731,2257,892,2397,420,2688,340,6,1274,2007,3309,1069,124,823,1074,299,518,271,428,685,639,755,2413,1745,640,2620,1076,1184,2188,1078,2091,2189,1369,521,577,1079,54,1930,2475,1561,3542,906,2094,1286,909,2190,1565,2628,527,1193,583,1758,1840,1462,104,833,2846... | 0.356288737373063,0.3013745602323828,-0.07177053677304059,-0.07177053677304059,0.5235857910422159,1.1111613487779155,0.2468749208094238,0.5802262548677871,1.3603994825359238,0.8703239336226946,-0.12354184408581988,1.1726596350338454,1.2972687676797499,0.8703239336226946,0.032894232644399175,-0.27667722707748915,0.52358... | 3,643 |
Abnormal reticulocyte morphology | 15 | 33 | 3.08723 | 0.00202 | P46777,P61254,Q07020,P62081,P62857,P62244,P62899,P61353,P42766,P18077,P49327,Q9Y3A5,P62847,P62854,P61313 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 125,80,531,434,436,435,47,592,15,341,581,562,25,64,31 | 1435,1445,1360,747,2010,2180,2335,341,2619,2093,1752,15,125,2477,1649,581,2774,643,80,31,592,434,435,25,64,436,47,1091,531,2359,1220,1805,562 | 0.19278333017529875,0.19278333017529875,0.2468749208094238,0.637316184085691,-0.12354184408581988,-0.2259898614760554,-0.3270137385950589,1.1111613487779155,-0.5249504103946776,-0.174946489808922,0.032894232644399175,3.528575244639867,1.8186080128566493,-0.426654247568139,0.08579910129584352,0.8113589567569786,-0.62193... | 3,643 |
G2 m checkpoints | 43 | 95 | 3.07799 | 0.002084 | O95067,P14635,Q14191,Q9NWV8,Q15008,P25789,P60900,P25788,O43242,O43913,P25205,P24941,P28066,P33991,P49720,P62333,O00487,O60921,Q9UBD5,Q7L590,P35244,P62191,P20618,P61289,P25786,P25787,P15927,Q92530,P33992,O14757,P55036,Q8N2W9,Q14997,Q13535,P51530,P49736,O75832,P51665,Q9Y619,Q13200,Q99741,Q99436,Q92547 | Processes and pathways | Reactome Pathways | msigdb_reactome | 6,124,772,951,537,755,644,639,510,511,271,518,640,521,527,529,884,892,459,184,54,914,299,433,428,685,823,495,577,337,589,107,238,105,104,583,340,833,807,352,941,939,545 | 1263,1913,1914,884,337,1347,510,511,1731,892,2397,2688,340,6,1274,2007,3309,1069,124,823,1074,299,518,271,428,685,639,755,2413,1745,640,2620,1076,1184,2189,1369,521,577,1079,54,1930,2475,1561,906,2094,1286,2190,2628,527,1193,583,1840,104,833,2420,589,644,2200,433,2031,914,1659,1847,529,1848,1380,2106,1941,2211,352,3119... | 0.3013745602323828,-0.07177053677304059,-0.07177053677304059,0.5235857910422159,1.1111613487779155,0.2468749208094238,0.8703239336226946,0.8703239336226946,0.032894232644399175,0.5235857910422159,-0.37700443540698164,-0.5736061024396271,1.1111613487779155,4.3689581005135825,0.3013745602323828,-0.12354184408581988,-1.17... | 3,643 |
Abnormal erythrocyte enzyme level | 13 | 21 | 3.069502 | 0.002144 | P46777,P61254,Q07020,P62081,P62857,P62244,P62899,P61353,P42766,P18077,P62847,P62854,P61313 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 125,80,531,434,436,435,47,592,15,341,25,64,31 | 2406,747,341,1752,15,125,2477,643,1468,80,31,592,434,435,25,64,436,47,1091,531,3612 | -0.37700443540698164,0.637316184085691,1.1111613487779155,0.032894232644399175,3.528575244639867,1.8186080128566493,-0.426654247568139,0.7528747198305642,0.19278333017529875,2.093521364597626,2.8984160204542766,0.8113589567569786,0.9897296751660267,0.9897296751660267,3.1303209321554855,2.234541210932711,0.9897296751660... | 3,643 |
Catalytic activity acting on dna | 45 | 99 | 3.064678 | 0.002179 | Q92499,Q9H4L7,Q14191,Q9Y620,P43246,P13010,Q2NKX8,Q12873,Q8WVB6,Q07864,P25205,P18074,O14981,Q66K74,P33991,P52701,Q96S55,Q9H2U1,O94761,P26358,Q8N3C0,P19447,P28340,Q16658,P27695,Q13283,Q9HCK8,Q96RR1,Q14839,Q92889,P33992,P46063,Q9NR33,P18858,P51530,P49736,P39748,P35251,Q96FZ2,P29372,P49916,P09884,O14646,Q12830,Q14527 | Functions | GO Molecular function | msigdb_gomf | 544,404,772,962,997,749,391,27,153,768,271,270,30,443,521,163,861,726,297,60,1027,427,687,1019,76,1014,217,366,703,95,577,579,1044,100,104,583,345,101,792,231,831,982,225,119,132 | 1999,225,30,2003,2608,2259,1353,297,2543,982,2334,2703,1362,2086,749,1831,1279,270,100,1641,427,1366,271,60,76,687,2339,231,521,577,1079,1930,2475,101,1751,345,2094,1286,997,579,3518,583,831,1840,104,1464,163,2420,1004,2850,768,2636,2209,119,27,1014,772,1206,132,1776,703,1490,1019,391,443,1120,1311,1869,2864,1027,1409,... | -0.12354184408581988,1.3603994825359238,2.8984160204542766,-0.12354184408581988,-0.5249504103946776,-0.27667722707748915,0.2468749208094238,1.1726596350338454,-0.4759679989713774,0.4673874574355663,-0.3270137385950589,-0.5736061024396271,0.2468749208094238,-0.174946489808922,0.637316184085691,-0.019627057122083305,0.30... | 3,643 |
Acute myeloid leukemia | 17 | 34 | 3.037392 | 0.002386 | P46777,P61254,Q07020,P62081,P62857,P62244,P62899,P61353,P42766,P18077,P11766,Q9Y3A5,Q5F1R6,P62847,P62854,P61313,P62263 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 125,80,531,434,436,435,47,592,15,341,473,562,93,25,64,31,348 | 2259,976,3309,1924,747,473,341,1749,1752,15,125,2477,2420,643,913,80,31,592,434,435,348,25,64,436,47,1091,531,2214,1101,93,1862,2304,1047,562 | -0.27667722707748915,0.4673874574355663,-1.1783350652217268,-0.07177053677304059,0.637316184085691,0.9297779869287993,1.1111613487779155,0.032894232644399175,0.032894232644399175,3.528575244639867,1.8186080128566493,-0.426654247568139,-0.37700443540698164,0.7528747198305642,0.5235857910422159,2.093521364597626,2.898416... | 3,643 |
Endonuclease activity active with either ribo or deoxyribonucleic acids and producing 5 phosphomonoesters | 9 | 18 | 3.035517 | 0.002401 | Q9BQG2,O75818,Q96DE0,Q99575,P51530,P39748,P27695,Q96F86,Q9UK59 | Functions | GO Molecular function | msigdb_gomf | 170,339,46,322,104,345,76,608,374 | 1916,742,339,76,345,104,1381,1019,46,608,322,612,170,1977,2745,374,1900,2387 | -0.07177053677304059,0.637316184085691,1.1111613487779155,2.093521364597626,1.1111613487779155,1.954875734282166,0.2468749208094238,0.4673874574355663,2.5974544418434338,0.8113589567569786,1.1726596350338454,0.8113589567569786,1.6186732764752128,-0.07177053677304059,-0.5736061024396271,1.1111613487779155,-0.01962705712... | 3,643 |
Macrocytic anemia | 20 | 36 | 3.01005 | 0.002612 | P46777,P42766,Q9Y3A5,O00429,P62847,P61313,P60866,Q07020,P62899,P62854,P61254,P62081,P62857,P11586,P62244,Q5F1R6,P00374,P61353,P18077,P62263 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 125,15,562,738,25,31,643,531,47,64,80,434,436,683,435,93,89,592,341,348 | 738,1436,2687,1175,89,980,747,1638,683,341,1075,1752,15,125,2477,643,913,80,31,592,434,435,348,25,64,436,47,1091,531,93,3076,1862,1703,1254,1338,562 | 0.637316184085691,0.19278333017529875,-0.5736061024396271,0.356288737373063,2.0239015433854965,0.4673874574355663,0.637316184085691,0.08579910129584352,0.6948631006681812,1.1111613487779155,0.41162409949645146,0.032894232644399175,3.528575244639867,1.8186080128566493,-0.426654247568139,0.7528747198305642,0.523585791042... | 3,643 |
P53 signaling pathway | 10 | 16 | 3.002199 | 0.00268 | P24941,P14635,O95067,O14757,Q00534,P11802,Q13535,Q7LG56,P42574,P49815 | Processes and pathways | KEGG Pathways | msigdb_kegg | 518,124,6,337,252,194,105,141,77,117 | 1434,2254,337,6,3309,1069,194,124,518,1185,77,581,117,252,105,141 | 0.19278333017529875,-0.27667722707748915,1.1111613487779155,4.3689581005135825,-1.1783350652217268,0.41162409949645146,1.4883650140779006,1.8186080128566493,0.8703239336226946,0.356288737373063,2.093521364597626,0.8113589567569786,1.8864444012100539,1.2972687676797499,1.954875734282166,1.7513670427695411 | 3,643 |
Endoribonuclease activity producing 5 phosphomonoesters | 8 | 16 | 2.91848 | 0.003517 | Q9BQG2,O75818,Q96DE0,Q99575,P39748,P27695,Q96F86,Q9UK59 | Functions | GO Molecular function | msigdb_gomf | 170,339,46,322,345,76,608,374 | 1916,742,339,76,345,1381,46,608,322,612,170,1977,2745,374,1900,2387 | -0.07177053677304059,0.637316184085691,1.1111613487779155,2.093521364597626,1.1111613487779155,0.2468749208094238,2.5974544418434338,0.8113589567569786,1.1726596350338454,0.8113589567569786,1.6186732764752128,-0.07177053677304059,-0.5736061024396271,1.1111613487779155,-0.019627057122083305,-0.3270137385950589 | 3,643 |
Negative regulation of ubiquitin protein transferase activity | 8 | 15 | 2.913565 | 0.003573 | P46777,O43684,Q8TDB6,P62081,Q13257,P62841,Q12834,P61927 | Processes and pathways | GO Biological process | msigdb_gobp | 125,249,40,434,651,24,180,178 | 249,2257,2079,125,643,178,434,1090,24,1091,180,651,40,2130,2067 | 1.2972687676797499,-0.27667722707748915,-0.174946489808922,1.8186080128566493,0.7528747198305642,1.553221452559307,0.9897296751660267,0.41162409949645146,3.1303209321554855,0.41162409949645146,1.553221452559307,0.7528747198305642,2.6718102012330496,-0.174946489808922,-0.12354184408581988 | 3,643 |
Dna repair | 52 | 132 | 2.90772 | 0.003641 | Q14191,P43246,P13010,Q9NZJ0,Q9UNS2,O94782,Q9NWV8,P20585,P25490,Q07864,P18074,P51948,P24941,P52701,Q92905,P78527,P54725,O60921,P41208,Q14694,Q9UNS1,P35244,Q6P6C2,P23193,P09874,Q8TAF3,P38398,Q8N3C0,P19447,Q8N9N2,Q9UGN5,P28340,Q16658,P15927,P27695,Q7L5N1,Q9NVI1,Q92889,P62875,Q8TAT6,Q9NR33,O14757,Q8N2W9,P18858,Q13535,P5153... | Processes and pathways | Reactome Pathways | msigdb_reactome | 772,997,749,291,560,380,951,381,638,768,270,274,518,163,717,165,528,892,523,920,333,54,709,300,298,203,906,1027,427,1029,620,687,1019,823,76,491,219,95,696,788,1044,337,107,100,105,104,1040,345,101,231,831,545 | 1432,337,1824,2003,2608,2465,892,2397,3516,380,1274,3110,2007,3309,3050,298,1362,2086,749,1831,823,270,100,1641,2410,427,381,300,1744,518,638,1745,76,687,231,1838,2838,54,1930,2475,101,906,345,2094,1286,523,997,1650,831,1840,104,274,2909,163,1466,2420,528,2964,1764,2558,1004,1089,2200,2281,2202,2030,2635,1848,696,165,2... | 0.19278333017529875,1.1111613487779155,-0.019627057122083305,-0.12354184408581988,-0.5249504103946776,-0.426654247568139,0.5235857910422159,-0.37700443540698164,-1.6955736238491228,1.050187786825878,0.3013745602323828,-0.9054161621172195,-0.12354184408581988,-1.1783350652217268,-0.8589259728879383,1.1726596350338454,0.... | 3,643 |
Gtpase binding | 48 | 108 | 2.904567 | 0.003678 | Q9H2M9,Q9UJY4,O00410,Q9UI26,P07737,P55196,O60879,P31150,P07814,O00429,Q14C86,Q12904,P21333,P67809,Q8IWJ2,Q8TEX9,Q07960,Q8WUW1,Q92597,Q9P258,P46940,Q8TD16,Q9HAV4,Q5VSL9,Q9H8V3,Q9Y333,Q96S59,Q676U5,Q7L576,Q9P2R3,O43747,P41252,Q01968,Q92973,Q13576,O95373,O14980,Q9Y5L0,O75116,Q9H4M9,Q16513,O60610,Q96N67,Q8IUD2,P61970,P4981... | Functions | GO Molecular function | msigdb_gomf | 944,672,964,149,746,1002,20,995,635,738,281,770,989,32,1128,1132,36,1134,1135,330,525,186,328,1116,327,59,611,708,599,876,815,693,1012,1032,701,571,811,375,87,109,775,468,1037,106,1008,117,664,547 | 2253,964,738,2680,2818,811,1918,1825,815,468,20,87,1350,571,2832,746,635,1180,3052,1555,989,2837,995,693,1754,1565,525,1758,117,1651,3454,1462,2479,1654,1087,1002,2634,1008,2562,2099,32,1664,1012,36,2107,770,1666,1667,1484,1947,2214,701,2357,281,1394,3470,1581,775,1675,1116,708,2786,2498,599,106,1128,2733,1875,186,1132... | -0.27667722707748915,0.4673874574355663,0.637316184085691,-0.5736061024396271,-0.6699553268222116,0.5802262548677871,-0.07177053677304059,-0.019627057122083305,0.5802262548677871,0.9297779869287993,3.2878627229397095,2.0239015433854965,0.2468749208094238,0.8113589567569786,-0.6699553268222116,0.637316184085691,0.752874... | 3,643 |
Neoplasm of the colon | 23 | 39 | 2.895769 | 0.003782 | P46777,Q13485,O43684,P42766,P20585,P08708,P62847,P61313,P60866,P52701,Q07020,P62899,P62854,O43683,P61254,P62081,P62857,P62244,Q8NFG4,P28340,P61353,P18077,P54277 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 125,254,249,15,381,747,25,31,643,163,531,47,64,296,80,434,436,435,82,687,592,341,347 | 296,249,2257,3309,747,1926,341,381,3313,687,2550,906,1752,15,997,125,2477,163,2420,347,643,80,31,592,434,435,25,64,436,47,1091,531,768,254,1398,1019,1681,82,2050 | 1.1726596350338454,1.2972687676797499,-0.27667722707748915,-1.1783350652217268,0.637316184085691,-0.07177053677304059,1.1111613487779155,1.050187786825878,-1.1783350652217268,0.6948631006681812,-0.4759679989713774,0.5235857910422159,0.032894232644399175,3.528575244639867,0.4673874574355663,1.8186080128566493,-0.4266542... | 3,643 |
Thrombocytosis | 17 | 30 | 2.884359 | 0.003922 | P46777,P60866,P61254,Q07020,P62081,P62857,P62244,P62899,P61353,P42766,Q9ULP9,P18077,Q6PGP7,P62263,P62847,P62854,P61313 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 125,643,80,531,434,436,435,47,592,15,50,341,120,348,25,64,31 | 976,747,2178,683,341,2411,3017,3285,905,3336,1752,15,125,2477,643,80,31,592,434,435,348,25,64,436,47,1091,531,1107,120,50 | 0.4673874574355663,0.637316184085691,-0.2259898614760554,0.6948631006681812,1.1111613487779155,-0.37700443540698164,-0.8121388295267228,-1.1335470777869139,0.5235857910422159,-1.2228519251976793,0.032894232644399175,3.528575244639867,1.8186080128566493,-0.426654247568139,0.7528747198305642,2.093521364597626,2.898416020... | 3,643 |
Double strand break repair | 46 | 112 | 2.876134 | 0.004026 | Q92499,Q68E01,Q9H4L7,Q14191,Q9Y620,Q9Y3Z3,P13010,Q7Z4V5,Q9NWV8,P25490,P26583,P25205,P33991,Q8TDB6,Q9BUR4,Q96FW1,P78527,O00487,Q9UBB9,O60921,Q96T76,Q9UNS1,P35244,O94761,Q9UBU8,P38398,O95071,P09874,Q8TAF3,Q9UGN5,P61160,P15927,Q6KC79,Q92889,P33992,P46063,Q9NWY4,O14757,Q8N2W9,P09429,P51530,P49736,P39748,Q96FZ2,P49916,Q9NPF... | Processes and pathways | GO Biological process | msigdb_gobp | 544,259,404,772,962,413,749,142,951,638,900,271,521,40,41,719,165,884,458,892,722,333,54,297,207,906,424,298,203,620,432,823,490,95,577,579,111,337,107,471,104,583,345,792,831,799 | 1541,884,337,2003,3278,1732,892,2397,2688,297,424,2694,3110,2007,3309,471,298,982,2086,749,823,1641,1929,271,638,900,1745,521,577,1079,54,2271,2019,906,345,997,579,3518,583,831,1840,104,1466,2420,1764,1089,2200,432,165,3118,2211,1204,3432,772,1776,1577,1669,1398,3558,1019,2495,3342,259,490,2576,2863,142,3081,107,3404,2... | 0.13909345271370782,0.5235857910422159,1.1111613487779155,-0.12354184408581988,-1.1335470777869139,0.032894232644399175,0.5235857910422159,-0.37700443540698164,-0.5736061024396271,1.1726596350338454,0.9897296751660267,-0.5736061024396271,-0.9054161621172195,-0.12354184408581988,-1.1783350652217268,0.9297779869287993,1.... | 3,643 |
Large ribosomal subunit | 31 | 78 | 2.854693 | 0.004308 | P46777,P36578,Q9NVS2,P40429,P42766,P63173,P62917,Q5T653,Q9Y3U8,P62424,P61313,P84098,Q9NP64,P62910,P62899,P83881,P61927,P61513,P26373,P62750,P46778,P61254,P39023,P50914,Q9P015,P46776,Q02878,P18077,P27635,P46779,Q02543 | Localization | GO Cellular component | msigdb_gocc | 125,250,148,385,15,388,279,26,159,278,31,33,37,39,47,439,178,62,301,306,197,80,196,431,220,91,237,341,343,232,350 | 2330,2083,1070,341,1554,751,301,343,1077,1370,904,250,196,385,15,91,125,197,232,911,999,2022,431,2710,2557,80,31,592,62,178,278,306,1090,646,47,1198,39,1091,279,388,483,439,33,350,237,531,2970,1774,2858,26,2861,2728,3402,2580,2438,2370,3378,2052,2588,1705,2592,2670,3199,2996,3301,2517,1985,2745,37,2063,3096,148,3202,21... | -0.3270137385950589,-0.174946489808922,0.41162409949645146,1.1111613487779155,0.13909345271370782,0.637316184085691,1.1726596350338454,1.1111613487779155,0.41162409949645146,0.2468749208094238,0.5235857910422159,1.2972687676797499,1.4883650140779006,1.050187786825878,3.528575244639867,2.0239015433854965,1.8186080128566... | 3,643 |
Protein serine threonine kinase activity | 33 | 103 | 2.850358 | 0.004367 | Q9UHY1,Q00534,P25098,P33981,Q9H4A3,P24941,Q8WZ42,Q7KZI7,Q86UE8,Q9BUB5,P41743,P78527,Q9BRS2,P42345,O14733,O43683,P54646,P11802,Q9BVS4,P46020,Q99986,O95747,O60885,O75116,Q9Y4B6,O14757,P53350,Q13535,P49840,Q96Q15,P25440,Q14004,Q96GX5 | Functions | GO Molecular function | msigdb_gomf | 264,252,12,520,171,518,169,445,316,451,162,165,323,524,53,296,303,194,216,78,500,88,567,87,114,337,588,105,584,548,229,353,399 | 53,337,2461,2819,1435,810,965,967,3305,296,2257,567,87,816,2170,3571,88,1636,1637,1069,1450,2334,194,3362,2337,1642,987,518,12,229,993,688,2092,520,162,524,78,1081,998,2419,1288,584,641,585,3189,3317,588,3151,303,1092,1382,165,252,1094,1386,2107,2353,1667,1388,1947,1772,2354,105,1299,1098,353,1773,3290,1104,2640,1581,7... | 2.377931653766487,1.1111613487779155,-0.426654247568139,-0.6699553268222116,0.19278333017529875,0.5802262548677871,0.4673874574355663,0.4673874574355663,-1.1783350652217268,1.1726596350338454,-0.27667722707748915,0.8113589567569786,2.0239015433854965,0.5802262548677871,-0.2259898614760554,-2.0610678175841555,2.02390154... | 3,643 |
Nf kappab binding | 6 | 16 | 2.845036 | 0.004441 | O95999,P49841,Q04721,P27695,P60900,Q04206 | Functions | GO Molecular function | msigdb_gomf | 4,641,351,76,644,648 | 2538,4,1924,1830,76,641,644,648,351,1390,2215,1865,1600,720,1800,2252 | -0.4759679989713774,4.54402937594712,-0.07177053677304059,-0.019627057122083305,2.093521364597626,0.7528747198305642,0.7528747198305642,0.7528747198305642,1.1111613487779155,0.2468749208094238,-0.2259898614760554,-0.019627057122083305,0.13909345271370782,0.6948631006681812,0.032894232644399175,-0.2259898614760554 | 3,643 |
Transsulfuration and onecarbon metabolism | 9 | 19 | 2.836292 | 0.004564 | P00374,P23526,P26358,P31153,P34896,P04818,P11586,P13995,P48507 | Processes and pathways | WikiPathways | msigdb_wp | 89,516,60,344,475,682,683,474,302 | 1436,740,89,682,683,474,516,60,344,475,2552,1931,1649,302,2629,1860,1703,1421,1907 | 0.19278333017529875,0.637316184085691,2.0239015433854965,0.6948631006681812,0.6948631006681812,0.9297779869287993,0.8703239336226946,2.234541210932711,1.1111613487779155,0.9297779869287993,-0.4759679989713774,-0.07177053677304059,0.08579910129584352,1.1726596350338454,-0.5249504103946776,-0.019627057122083305,0.0857991... | 3,643 |
Mitotic g1 phase and g1 s transition | 54 | 87 | 2.819348 | 0.004812 | P06400,P14635,Q00534,P56282,Q15008,P25789,P60900,P25788,O43242,O43913,Q07864,P25205,P51948,P28749,P24941,P28066,P33991,P49720,P62333,Q14181,Q13616,O00487,Q9UBD5,Q7L590,P35244,P62191,P20618,P61289,P25786,P04818,P25787,P11802,P15927,Q92530,P33993,P30154,P28072,P17980,P00374,P33992,Q9NR33,P55036,O75832,Q13309,P51665,P4973... | Processes and pathways | Reactome Pathways | msigdb_reactome | 5,124,252,1004,537,755,644,639,510,511,768,271,274,902,518,640,521,527,529,182,533,884,459,184,54,914,299,433,428,682,685,194,823,495,1079,1078,1076,1074,89,577,1044,589,340,839,833,583,830,829,807,352,941,982,939,349 | 1263,1913,1914,884,1347,510,511,1731,2688,340,89,1446,682,5,1069,3412,982,2703,194,1362,3467,124,823,1074,299,518,271,428,685,639,755,1745,640,2620,1076,1184,902,2188,1078,1185,2092,521,577,1079,54,1561,2190,2628,829,830,527,1193,583,833,274,589,1004,644,433,914,1659,529,349,2777,252,1941,768,2209,352,839,3119,1390,533... | 0.3013745602323828,-0.07177053677304059,-0.07177053677304059,0.5235857910422159,0.2468749208094238,0.8703239336226946,0.8703239336226946,0.032894232644399175,-0.5736061024396271,1.1111613487779155,2.0239015433854965,0.19278333017529875,0.6948631006681812,4.54402937594712,0.41162409949645146,-1.3548095072485222,0.467387... | 3,643 |
Separation of sister chromatids | 56 | 115 | 2.817398 | 0.004841 | Q7Z5K2,O43684,Q13257,P68371,Q15008,Q96BT3,P25789,P60900,Q2NKX8,P25788,O43242,P28066,P49720,P62333,Q96EE3,Q9P258,O00487,Q7Z460,Q96EA4,Q12834,P62191,Q29RF7,O43683,O75122,Q13885,P20618,P43034,Q9NQS7,Q9NTI5,Q14204,P61289,Q14738,P25786,P25787,P63167,Q9BVA1,Q8NFH3,Q99661,Q92530,P30154,O14980,P28072,P17980,P55036,P53350,Q1499... | Processes and pathways | Reactome Pathways | msigdb_reactome | 541,249,651,1093,537,1229,755,644,391,639,510,640,527,529,860,330,884,851,1139,180,914,846,296,420,597,299,909,1158,873,308,433,310,428,685,437,1149,1030,1145,495,1078,811,1076,1074,589,588,238,340,226,835,833,1042,352,354,939,1109,546 | 1170,1263,1913,1914,884,1347,811,226,510,2002,296,249,3278,2257,420,340,1549,1074,299,428,685,639,755,640,2620,1076,1184,2188,1078,2091,1561,3542,909,2190,1565,2628,527,1193,1758,1462,833,2846,588,589,835,2911,644,433,914,1659,529,437,1093,1941,2853,180,1481,352,651,1576,597,354,308,1777,1393,310,238,2638,537,1109,2573... | 0.356288737373063,0.3013745602323828,-0.07177053677304059,-0.07177053677304059,0.5235857910422159,0.2468749208094238,0.5802262548677871,1.3603994825359238,0.8703239336226946,-0.12354184408581988,1.1726596350338454,1.2972687676797499,-1.1335470777869139,-0.27667722707748915,0.9897296751660267,1.1111613487779155,0.139093... | 3,643 |
Dna replication | 51 | 95 | 2.802358 | 0.005073 | P56282,Q15008,P25789,P60900,P25788,O43242,O43913,Q07864,P25205,P24941,P28066,P33991,P49720,Q99436,P62333,Q14181,Q13616,O00487,Q9UBD5,Q7L590,P35244,P62191,P20618,P61289,P25786,P25787,P28340,P15927,Q92530,P33993,P28072,P17980,P33992,Q9NR33,P55036,Q9H1A4,Q14997,P18858,O75832,P51530,P49736,Q13309,P35251,P51665,Q9Y619,P3974... | Processes and pathways | Reactome Pathways | msigdb_reactome | 1004,537,755,644,639,510,511,768,271,518,640,521,527,939,529,182,533,884,459,184,54,914,299,433,428,685,687,823,495,1079,1076,1074,577,1044,589,1042,238,100,340,104,583,839,101,833,807,345,830,829,352,941,982 | 1263,1913,1914,884,1347,510,511,1731,1061,2688,340,982,1362,823,1074,100,299,518,271,428,685,639,755,1745,640,2620,1076,1184,687,2091,521,577,1079,54,1930,2475,101,1561,345,2094,1286,2190,2628,1650,829,830,527,1193,583,104,833,1375,589,1004,644,433,914,1659,529,1848,2777,1941,768,1481,352,839,3119,533,182,1776,2357,238... | 0.3013745602323828,-0.07177053677304059,-0.07177053677304059,0.5235857910422159,0.2468749208094238,0.8703239336226946,0.8703239336226946,0.032894232644399175,0.41162409949645146,-0.5736061024396271,1.1111613487779155,0.4673874574355663,0.2468749208094238,0.5802262548677871,0.41162409949645146,1.954875734282166,1.172659... | 3,643 |
Negative regulation of cell cycle | 44 | 110 | 2.800828 | 0.005097 | Q68E01,Q7Z5K2,P06400,P14635,Q00534,O43684,Q13257,P12270,Q9NZJ0,O43670,Q13769,Q9NWV8,P33981,Q13642,P28749,Q06124,P24941,Q96JB5,P78527,O60921,Q9UNS1,O43683,Q08J23,Q13564,P61254,Q15910,Q9Y3I1,P42574,P15927,O14745,O95373,Q5JVF3,Q969U7,O14757,Q12948,P53350,Q13535,P51530,Q9Y619,Q99741,Q96EB6,Q7Z7L1,Q8N6R0,Q92547 | Processes and pathways | GO Biological process | msigdb_gobp | 259,541,5,124,252,249,651,637,291,379,771,951,520,534,902,767,518,720,165,892,333,296,307,199,80,845,221,77,823,565,571,487,244,337,838,588,105,104,807,941,937,260,261,545 | 1432,964,565,337,3210,2002,2003,379,296,249,3278,2608,2257,892,2397,3179,2688,2399,571,3309,5,1069,1924,637,124,823,518,902,520,3018,906,1372,77,997,3518,2025,1840,1462,104,588,2420,80,165,252,1094,767,307,2211,838,3289,651,3119,105,199,534,771,2719,3340,1777,1208,1398,845,1673,1114,487,259,1498,3074,3075,2364,2436,541... | 0.19278333017529875,0.4673874574355663,0.8113589567569786,1.1111613487779155,-1.0431437506361978,-0.12354184408581988,-0.12354184408581988,1.050187786825878,1.1726596350338454,1.2972687676797499,-1.1335470777869139,-0.5249504103946776,-0.27667722707748915,0.5235857910422159,-0.37700443540698164,-0.997521253539814,-0.57... | 3,643 |
Abnormal forearm bone morphology | 7 | 24 | 2.779865 | 0.005438 | O94761,P61254,Q13535,Q14999,Q8NCM8,Q9NVI1,Q92889 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 297,80,105,18,22,219,95 | 632,297,1741,1926,2835,989,906,3020,1752,80,2034,105,18,2431,2491,490,22,95,3030,2300,1804,1805,944,219 | 0.7528747198305642,1.1726596350338454,0.032894232644399175,-0.07177053677304059,-0.6699553268222116,0.4673874574355663,0.5235857910422159,-0.8121388295267228,0.032894232644399175,2.093521364597626,-0.12354184408581988,1.954875734282166,3.528575244639867,-0.37700443540698164,-0.426654247568139,0.9297779869287993,3.20879... | 3,643 |
Ribonucleoprotein | 58 | 193 | 2.768737 | 0.005627 | P46777,P36578,Q9NVS2,P19474,P40429,P42766,Q9UQ80,P62841,P62847,Q5T653,Q9Y3U8,P62917,P62424,P61313,P15880,P84098,P63173,P62277,Q9NP64,O76094,P62910,Q07020,P25398,P62899,P83881,P63244,Q9Y333,P62854,P61927,P62753,P61513,Q8WVV9,P26373,P62701,P62750,P46778,P61254,P39023,P62241,P62244,P62081,P62857,P50914,P46782,Q9P015,Q9BUJ... | Functions | Protein Atlas Molecular function | protein_atlas_molecular_function | 125,250,148,11,385,15,293,24,25,26,159,279,278,31,269,33,388,387,37,514,39,531,160,47,439,438,59,64,178,63,62,205,301,305,306,197,80,196,304,435,434,436,431,430,220,369,91,348,245,483,237,341,343,232,480,350,118,481 | 1055,3141,3048,2394,2325,631,2259,514,2693,2330,2083,3563,2955,2332,747,2178,1070,3585,822,2179,2768,2702,2009,3014,269,341,1554,751,11,2548,3314,1366,160,301,343,1077,3365,2551,1370,904,250,1285,3581,1751,1752,196,385,15,91,125,197,232,1190,430,2477,911,999,2022,1567,431,3150,2845,1843,1290,2557,1845,2028,643,913,480,... | 0.41162409949645146,-0.9516133105392405,-0.8589259728879383,-0.37700443540698164,-0.3270137385950589,0.7528747198305642,-0.27667722707748915,0.8703239336226946,-0.5736061024396271,-0.3270137385950589,-0.174946489808922,-2.0213349377453547,-0.7650507386283446,-0.3270137385950589,0.637316184085691,-0.2259898614760554,0.4... | 3,643 |
Developmental glaucoma | 17 | 28 | 2.76055 | 0.00577 | P46777,P60866,Q9Y3Z3,Q86XI2,P61254,Q07020,P62081,P62857,P62244,P62899,P61353,P42766,O75792,P18077,P62847,P62854,P61313 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 125,643,413,317,80,531,434,436,435,47,592,15,742,341,25,64,31 | 742,747,341,989,2016,1752,15,125,2477,2910,643,80,31,592,434,435,25,64,436,47,1091,1012,531,838,317,3234,3533,413 | 0.637316184085691,0.637316184085691,1.1111613487779155,0.4673874574355663,-0.12354184408581988,0.032894232644399175,3.528575244639867,1.8186080128566493,-0.426654247568139,-0.717657624490921,0.7528747198305642,2.093521364597626,2.8984160204542766,0.8113589567569786,0.9897296751660267,0.9897296751660267,3.13032093215548... | 3,643 |
Ribosomal protein L2, domain 2 [IPR014722] | 7 | 14 | 2.750795 | 0.005945 | P62701,Q02878,P61254,P50914,Q14999,P62917,Q5T653 | Sequence | InterPro Superfamily | interpro_homologous_superfamily | 305,237,80,431,18,279,26 | 2074,2396,1274,431,80,305,279,482,237,2211,18,26,1137,3378 | -0.174946489808922,-0.37700443540698164,0.3013745602323828,0.9897296751660267,2.093521364597626,1.1726596350338454,1.234692175919743,0.9297779869287993,1.3603994825359238,-0.2259898614760554,3.528575244639867,3.1303209321554855,0.41162409949645146,-1.2671010666360616 | 3,643 |
Gastrointestinal carcinoma | 22 | 36 | 2.7491 | 0.005976 | P46777,Q13485,Q14191,P42766,P08708,P62847,P61313,P60866,P52701,Q07020,P62899,P62854,O43683,P63167,P61254,P62081,P62857,P62244,Q8NFG4,P28340,P61353,P18077 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 125,254,772,15,747,25,31,643,163,531,47,64,296,437,80,434,436,435,82,687,592,341 | 810,296,2257,2470,3309,747,3467,341,687,3018,1752,15,997,125,2477,163,643,80,31,592,434,435,25,64,436,47,1091,437,531,768,2353,254,772,1681,82,962 | 0.5802262548677871,1.1726596350338454,-0.27667722707748915,-0.426654247568139,-1.1783350652217268,0.637316184085691,-1.4844458628685837,1.1111613487779155,0.6948631006681812,-0.8121388295267228,0.032894232644399175,3.528575244639867,0.4673874574355663,1.8186080128566493,-0.426654247568139,1.6186732764752128,0.752874719... | 3,643 |
G1 to s cell cycle control | 18 | 29 | 2.742053 | 0.006106 | P51948,P33992,P06400,P24941,P14635,Q00534,P33991,O43913,Q14181,P11802,P49736,Q9UBD5,P15927,P49643,Q9Y619,P35244,Q07864,P25205 | Processes and pathways | WikiPathways | msigdb_wp | 274,577,5,518,124,252,521,511,182,194,583,459,823,830,807,54,768,271 | 511,1731,2688,3309,5,1069,194,1362,124,823,518,271,1745,521,577,1079,54,829,830,583,274,1004,252,768,3119,182,1776,459,807 | 0.8703239336226946,0.032894232644399175,-0.5736061024396271,-1.1783350652217268,4.54402937594712,0.41162409949645146,1.4883650140779006,0.2468749208094238,1.8186080128566493,0.5802262548677871,0.8703239336226946,1.234692175919743,0.032894232644399175,0.8703239336226946,0.8113589567569786,0.41162409949645146,2.377931653... | 3,643 |
Cell cycle phase transition | 67 | 176 | 2.741495 | 0.006116 | Q68E01,P06400,O95067,P14635,Q00534,O43684,Q13257,P12270,Q9NZJ0,Q7LG56,O43670,Q13769,P33981,Q13642,P49427,Q07864,Q06124,P18074,P51948,P24941,Q96JB5,P78527,Q13616,Q86Y37,Q9P258,Q93034,Q9Y570,Q7Z460,Q9UNS1,O43683,O75122,P62753,Q7L2J0,P19447,Q08J23,Q13564,P61254,P61289,P11802,Q15910,Q9Y3I1,Q04637,Q6P1X5,P27695,Q9BVS4,P3524... | Processes and pathways | GO Biological process | msigdb_gobp | 259,5,6,124,252,249,651,637,291,141,379,771,520,534,272,768,767,270,274,518,720,165,533,712,330,857,464,851,333,296,420,63,71,427,307,199,80,433,194,845,221,595,358,76,216,578,823,810,501,567,487,244,337,465,588,839,105,104,780,807,478,483,805,260,261,399,545 | 1432,1999,465,337,810,2002,2003,3410,379,296,249,2538,3278,2257,567,892,2397,420,1736,3179,2688,2399,6,1357,2082,3309,2545,2831,5,1069,1358,1924,3602,3390,194,637,124,1182,823,270,1555,427,3498,991,518,76,902,2091,2189,1185,520,578,906,997,3221,1934,272,1840,478,1462,104,3061,274,588,2420,2196,80,433,63,1938,165,1383,4... | 0.19278333017529875,-0.12354184408581988,0.9297779869287993,1.1111613487779155,0.5802262548677871,-0.12354184408581988,-0.12354184408581988,-1.3548095072485222,1.050187786825878,1.1726596350338454,1.2972687676797499,-0.4759679989713774,-1.1335470777869139,-0.27667722707748915,0.8113589567569786,0.5235857910422159,-0.37... | 3,643 |
Positive regulation of signal transduction by p53 class mediator | 8 | 11 | 2.730759 | 0.006319 | P60866,O43324,P61254,P62081,Q13535,P63241,P62841,P61927 | Processes and pathways | GO Biological process | msigdb_gobp | 643,566,80,434,105,482,24,178 | 566,2268,643,80,178,434,1090,24,482,105,720 | 0.8113589567569786,-0.27667722707748915,0.7528747198305642,2.093521364597626,1.553221452559307,0.9897296751660267,0.41162409949645146,3.1303209321554855,0.9297779869287993,1.954875734282166,0.6948631006681812 | 3,643 |
Aplasia of the fingers | 17 | 31 | 2.715292 | 0.006622 | O94761,P46777,P61254,Q07020,P62081,P62857,P62244,P62899,Q92889,P42766,P61353,Q6KC79,P18077,Q9NVI1,P62847,P62854,P61313 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 297,125,80,531,434,436,435,47,95,15,592,490,341,219,25,64,31 | 1913,3571,297,3333,747,341,2769,1752,15,125,2477,643,80,31,592,434,435,25,64,436,47,1091,531,3155,1485,2431,490,95,3270,1805,219 | -0.07177053677304059,-2.0610678175841555,1.1726596350338454,-1.2228519251976793,0.637316184085691,1.1111613487779155,-0.6219395983652799,0.032894232644399175,3.528575244639867,1.8186080128566493,-0.426654247568139,0.7528747198305642,2.093521364597626,2.8984160204542766,0.8113589567569786,0.9897296751660267,0.9897296751... | 3,643 |
Hematological neoplasm | 34 | 90 | 2.710057 | 0.006727 | P46777,O95999,P06400,O43684,Q9Y3Z3,P42766,Q9Y3A5,P62847,P61313,O76094,P33991,Q9BUR4,P52701,Q07020,P62899,P62854,O43683,O94761,Q08J23,P61254,P62244,P62081,P62857,Q5F1R6,Q9NVI1,Q92889,P17812,O60885,P61353,P50851,P18077,P11766,O95394,P62263 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 125,4,5,249,413,15,562,25,31,514,521,41,163,531,47,64,296,297,307,80,435,434,436,93,219,95,575,567,592,586,341,473,469,348 | 296,249,2257,2259,567,2397,976,742,514,297,469,3524,4,2081,2406,2470,3308,3309,5,1924,747,473,575,341,1365,1075,2412,3285,521,1749,906,3316,1752,2020,15,997,3518,125,2477,581,586,163,1376,2420,2910,643,913,80,31,592,434,435,348,25,64,436,2562,47,1091,1385,1386,767,531,768,307,3432,2214,1101,1778,1398,93,1681,1862,3234,... | 1.1726596350338454,1.2972687676797499,-0.27667722707748915,-0.27667722707748915,0.8113589567569786,-0.37700443540698164,0.4673874574355663,0.637316184085691,0.8703239336226946,1.1726596350338454,0.9297779869287993,-1.7370854297366594,4.54402937594712,-0.174946489808922,-0.37700443540698164,-0.426654247568139,-1.1783350... | 3,643 |
Ubl conjugation pathway | 53 | 165 | 2.702544 | 0.006881 | Q15018,Q7Z569,Q8TEB1,Q9Y2Z0,Q15386,P19474,Q96J02,Q9Y4P1,Q9NR09,Q14999,Q9NZJ0,O94782,P49427,Q9BZL1,Q9Y4E8,Q14139,P54578,P61962,Q96ME1,Q8TDB6,Q96FW1,Q63HN8,Q9GZR1,Q9UPN9,Q13616,Q86X83,Q15345,Q7Z6Z7,Q12834,Q8N806,Q7L5Y9,O15344,Q9ULT8,O95071,Q8TAF3,Q9GZZ9,Q13564,Q9UPU5,Q9Y314,Q9Y3I1,Q86UV5,Q93008,O95352,Q9H000,Q9NT62,Q5GLZ... | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 538,143,8,150,256,11,146,414,557,18,291,380,272,28,29,34,642,277,721,40,719,45,452,462,533,185,441,315,180,604,313,294,734,424,203,614,199,623,624,221,360,496,570,370,371,357,114,247,107,661,657,401,132 | 1261,1264,884,1917,1057,294,679,2897,817,1350,3516,1738,380,2400,2690,2541,424,743,570,1066,3282,1274,2087,11,1075,2412,2091,906,907,1460,272,1758,912,642,2964,1764,2278,1006,2713,2200,2030,277,2777,1938,1385,917,1200,180,1201,1481,1298,839,199,533,1099,1485,1205,34,3318,1207,132,1577,920,18,2920,538,441,1397,1106,256,... | 0.3013745602323828,0.3013745602323828,0.5235857910422159,-0.07177053677304059,0.41162409949645146,1.1726596350338454,0.6948631006681812,-0.717657624490921,0.5802262548677871,0.2468749208094238,-1.6955736238491228,0.032894232644399175,1.050187786825878,-0.37700443540698164,-0.5736061024396271,-0.4759679989713774,0.98972... | 3,643 |
Enzyme activator activity | 32 | 128 | 2.68552 | 0.007242 | Q14185,O95999,Q13017,Q9BTW9,P14635,Q6GYQ0,Q14C86,Q9Y263,Q4KMP7,O60343,Q9H4A3,P51948,Q07960,Q7KZI7,Q6R327,Q8TDB6,Q86XI2,Q9ULP9,Q12834,Q9H8V3,P63244,Q8IYB5,P61289,P63167,Q14738,Q8NFG4,P42574,P49815,Q15257,Q14997,P35251,Q92888 | Functions | GO Molecular function | msigdb_gomf | 131,4,128,550,124,284,281,157,392,512,171,274,36,445,444,40,317,50,180,327,438,201,433,437,310,82,77,117,486,238,101,262 | 738,884,1999,2254,1172,3358,3580,512,2398,820,2170,2899,4,2545,3389,3390,3360,1362,3467,749,124,3547,1365,2837,995,101,1560,3220,1563,77,1754,1565,525,3491,1758,117,1651,274,2274,2481,1763,1764,1293,433,2775,437,438,1938,1012,1386,1941,36,180,128,2353,1667,701,131,310,238,281,2113,1394,486,1105,924,2216,2359,2041,1401,... | 0.637316184085691,0.5235857910422159,-0.12354184408581988,-0.27667722707748915,0.356288737373063,-1.2671010666360616,-2.179008332714831,0.8703239336226946,-0.37700443540698164,0.5802262548677871,-0.2259898614760554,-0.717657624490921,4.54402937594712,-0.4759679989713774,-1.3110858336621674,-1.3110858336621674,-1.267101... | 3,643 |
Cyclin dependent protein kinase holoenzyme complex | 8 | 15 | 2.671784 | 0.007545 | P51948,P24941,P14635,O95067,Q00534,P11802,P49736,Q14004 | Localization | GO Cellular component | msigdb_gocc | 274,518,124,6,252,194,583,353 | 2170,6,1069,194,1362,124,518,583,585,274,252,1094,353,3237,1620 | -0.2259898614760554,4.3689581005135825,0.41162409949645146,1.4883650140779006,0.2468749208094238,1.8186080128566493,0.8703239336226946,0.8113589567569786,0.8113589567569786,1.234692175919743,1.2972687676797499,0.41162409949645146,1.1111613487779155,-1.0431437506361978,0.13909345271370782 | 3,643 |
Nonimmune hydrops fetalis | 14 | 28 | 2.662203 | 0.007763 | P46777,P61254,Q07020,P62081,P62857,P62244,P62899,P61353,P42766,P18077,Q7L590,P62847,P62854,P61313 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 125,80,531,434,436,435,47,592,15,341,184,25,64,31 | 1546,2828,3308,2084,747,3360,341,1752,15,125,2477,643,80,31,592,434,435,25,64,436,47,1091,531,1300,184,3197,2244,3239 | 0.13909345271370782,-0.6699553268222116,-1.1783350652217268,-0.174946489808922,0.637316184085691,-1.2671010666360616,1.1111613487779155,0.032894232644399175,3.528575244639867,1.8186080128566493,-0.426654247568139,0.7528747198305642,2.093521364597626,2.8984160204542766,0.8113589567569786,0.9897296751660267,0.98972967516... | 3,643 |
Regulation of chromosome organization | 33 | 115 | 2.656888 | 0.007887 | Q7Z5K2,P06400,P14635,O43684,Q13257,P12270,O43670,Q9NTJ3,P33981,P25490,P78371,P51948,P24941,Q9GZR1,Q9H2U1,O14733,O43683,P26358,P09874,Q9BVS4,O95347,Q92889,Q5JVF3,Q969U7,Q96HR8,P53350,Q13535,P49711,P49736,P49368,P39748,Q15021,Q96Q15 | Processes and pathways | GO Biological process | msigdb_gobp | 541,5,124,249,651,637,379,290,520,638,647,274,518,452,726,53,296,60,298,216,569,95,487,244,245,588,105,103,583,582,345,654,548 | 53,2002,2003,379,296,249,3278,2608,2257,2259,2397,3179,569,3524,3110,5,3563,2768,298,2703,637,3467,749,124,899,1641,3314,1929,518,638,60,993,688,2091,520,1079,3018,345,1459,1372,3518,1192,582,103,583,3394,1840,1462,1463,1652,274,588,647,2035,1940,2851,1481,3289,651,1298,105,1485,2109,1777,1778,922,654,2358,1017,1398,48... | 2.377931653766487,-0.12354184408581988,-0.12354184408581988,1.050187786825878,1.1726596350338454,1.2972687676797499,-1.1335470777869139,-0.5249504103946776,-0.27667722707748915,-0.27667722707748915,-0.37700443540698164,-0.997521253539814,0.8113589567569786,-1.7370854297366594,-0.9054161621172195,4.54402937594712,-2.021... | 3,643 |
Neoplasm of the skeletal system | 25 | 45 | 2.650304 | 0.008042 | P46777,P06400,Q14191,Q9Y3Z3,P42766,P48735,O75792,P08708,P62847,P61313,P60866,P52701,Q07020,P62899,P62854,O94761,P61254,P62081,P62857,P62244,P61353,P18077,O75874,P54277,P49815 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 125,5,772,413,15,16,742,747,25,31,643,163,531,47,64,297,80,434,436,435,592,341,227,347,117 | 1348,3278,742,227,297,3333,3309,5,747,1926,341,1752,15,997,125,2477,16,117,163,347,2910,643,80,31,592,434,435,25,64,436,47,1091,767,531,1013,2213,1772,772,1019,1681,3234,2987,1042,2144,413 | 0.2468749208094238,-1.1335470777869139,0.637316184085691,1.3603994825359238,1.1726596350338454,-1.2228519251976793,-1.1783350652217268,4.54402937594712,0.637316184085691,-0.07177053677304059,1.1111613487779155,0.032894232644399175,3.528575244639867,0.4673874574355663,1.8186080128566493,-0.426654247568139,3.528575244639... | 3,643 |
Telomere c strand lagging strand synthesis | 11 | 23 | 2.649688 | 0.008057 | Q14191,P18858,Q14181,P51530,P28340,P39748,P35251,P15927,P49643,P35244,Q8WVB6 | Processes and pathways | Reactome Pathways | msigdb_reactome | 772,100,182,104,687,345,101,823,830,54,153 | 982,1362,823,100,1745,687,54,1930,2475,101,345,2094,1286,1650,829,830,104,2420,182,772,153,2064,3205 | 0.4673874574355663,0.2468749208094238,0.5802262548677871,1.954875734282166,0.032894232644399175,0.6948631006681812,2.377931653766487,-0.07177053677304059,-0.426654247568139,1.954875734282166,1.1111613487779155,-0.174946489808922,0.3013745602323828,0.08579910129584352,0.5802262548677871,0.5802262548677871,1.954875734282... | 3,643 |
Coarctation of aorta | 23 | 42 | 2.637618 | 0.008349 | P46777,Q13485,O43684,Q9Y5S9,P42766,P55263,P08708,P62847,P61313,Q06124,P60866,Q07020,P62899,P62854,O43683,P61254,P62081,P62857,P62244,Q14839,P61353,P18077,P49711 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 125,254,249,675,15,386,747,25,31,767,643,531,47,64,296,80,434,436,435,703,592,341,103 | 296,249,2257,2470,747,341,2472,1365,1187,1752,15,125,2477,103,1085,386,643,80,31,592,434,2350,435,25,64,436,47,1091,1386,767,531,254,703,1398,2497,2930,858,3036,1722,3352,1168,675 | 1.1726596350338454,1.2972687676797499,-0.27667722707748915,-0.426654247568139,0.637316184085691,1.1111613487779155,-0.426654247568139,0.2468749208094238,0.356288737373063,0.032894232644399175,3.528575244639867,1.8186080128566493,-0.426654247568139,1.954875734282166,0.41162409949645146,1.050187786825878,0.75287471983056... | 3,643 |
Condensation of prophase chromosomes | 7 | 11 | 2.618413 | 0.008834 | P06400,P14635,Q86XI2,P53350,P42695,Q9NTJ3,O95347 | Processes and pathways | Reactome Pathways | msigdb_reactome | 5,124,317,588,429,290,569 | 569,5,1069,124,429,588,1848,1472,317,290,805 | 0.8113589567569786,4.54402937594712,0.41162409949645146,1.8186080128566493,0.9897296751660267,0.8113589567569786,-0.019627057122083305,0.19278333017529875,1.1726596350338454,1.234692175919743,0.637316184085691 | 3,643 |
Integrated cancer pathway | 7 | 18 | 2.616452 | 0.008885 | P06400,P24941,O14757,P52701,P11802,Q13535,P42574 | Processes and pathways | WikiPathways | msigdb_wp | 5,518,337,163,194,105,77 | 337,3309,5,1069,194,518,906,1753,77,997,1840,163,588,2420,105,1694,2590,1804 | 1.1111613487779155,-1.1783350652217268,4.54402937594712,0.41162409949645146,1.4883650140779006,0.8703239336226946,0.5235857910422159,0.032894232644399175,2.093521364597626,0.4673874574355663,-0.019627057122083305,1.6186732764752128,0.8113589567569786,-0.37700443540698164,1.954875734282166,0.08579910129584352,-0.4759679... | 3,643 |
Regulation of mitotic cell cycle | 64 | 155 | 2.608616 | 0.009091 | Q68E01,Q69YH5,P06400,P14635,O43684,Q13257,P12270,Q14999,Q7LG56,Q13526,Q9NZJ0,O14744,O43670,Q9NWV8,P33981,Q13642,P28749,P18074,Q06124,P08243,P51948,P24941,Q96JB5,Q14166,P78527,Q9P258,O60921,P46940,P35244,Q7L5Y9,O43683,P43034,Q7L2J0,P19447,P61289,Q13564,P61254,P11802,Q15910,Q9Y3I1,Q04637,P15927,P27695,Q9BVS4,P35241,O1474... | Processes and pathways | GO Biological process | msigdb_gobp | 259,539,5,124,249,651,637,18,141,140,291,378,379,951,520,534,902,270,767,515,274,518,720,166,165,330,892,525,54,313,296,909,71,427,433,199,80,194,845,221,595,823,76,216,578,565,817,810,501,694,567,487,244,337,838,588,775,585,807,353,941,937,260,545 | 3274,1999,378,565,337,810,2002,2003,3410,379,296,249,3278,2257,567,892,2397,817,2825,1357,2082,3309,2545,5,1069,1358,515,194,637,124,823,3362,270,1555,427,991,518,76,902,2091,2189,1185,520,3018,578,54,3219,906,909,997,1564,525,1840,1462,585,694,3061,274,588,2420,2196,1658,80,433,1847,165,1383,3118,2035,595,767,1941,838... | -1.1335470777869139,-0.12354184408581988,1.050187786825878,0.8113589567569786,1.1111613487779155,0.5802262548677871,-0.12354184408581988,-0.12354184408581988,-1.3548095072485222,1.050187786825878,1.1726596350338454,1.2972687676797499,-1.1335470777869139,-0.27667722707748915,0.8113589567569786,0.5235857910422159,-0.3770... | 3,643 |
Neoplasm of the genitourinary tract | 26 | 80 | 2.604644 | 0.009197 | P46777,O95999,P06400,Q13485,O43684,P42766,P48735,P20585,P62847,P61313,P52701,P62899,Q13423,P62854,O43683,P63167,P61254,P62244,P62857,P62081,Q8NFG4,Q01844,P18077,O75874,P54277,P49815 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 125,4,5,254,249,15,16,381,25,31,163,47,55,64,296,437,80,435,436,434,82,92,341,227,347,117 | 810,296,249,973,2257,2397,227,4,2470,3333,3309,5,2902,747,1926,3467,341,381,1365,3313,687,2550,3018,3060,906,1752,3186,15,997,125,2477,16,117,1840,1289,163,2420,347,643,80,31,592,434,435,25,64,436,47,1091,437,92,3256,918,648,531,768,1298,55,254,3318,772,2359,1398,1019,3075,1681,1683,1026,82,2050,1694,2300,2873,3129,259... | 0.5802262548677871,1.1726596350338454,1.2972687676797499,0.4673874574355663,-0.27667722707748915,-0.37700443540698164,1.3603994825359238,4.54402937594712,-0.426654247568139,-1.2228519251976793,-1.1783350652217268,4.54402937594712,-0.717657624490921,0.637316184085691,-0.07177053677304059,-1.4844458628685837,1.1111613487... | 3,643 |
Protein k63 linked ubiquitination | 7 | 17 | 2.596233 | 0.009425 | O95071,Q96FW1,Q63HN8,P19474,Q96J02,Q9Y263,Q9ULT8 | Processes and pathways | GO Biological process | msigdb_gobp | 424,719,45,11,146,157,734 | 1999,424,1066,2087,11,2200,1201,1577,1493,45,719,146,797,734,2457,1428,157 | -0.12354184408581988,0.9897296751660267,0.41162409949645146,-0.174946489808922,3.8577220570211566,-0.2259898614760554,0.356288737373063,0.13909345271370782,0.19278333017529875,2.5974544418434338,0.6948631006681812,1.7513670427695411,0.637316184085691,0.6948631006681812,-0.37700443540698164,0.2468749208094238,1.68472196... | 3,643 |
Activation of the pre replicative complex | 19 | 26 | 2.585878 | 0.009713 | P56282,Q07864,O43913,P25205,P24941,P33991,Q14181,Q9UBD5,Q7L590,P35244,P15927,P33992,Q9NR33,P49736,P49643,P49642,Q9Y619,Q99741,P09884 | Processes and pathways | Reactome Pathways | msigdb_reactome | 1004,768,511,271,518,521,182,459,184,54,823,577,1044,583,830,829,807,941,982 | 511,1731,2688,982,823,518,271,1745,521,577,1079,54,829,830,583,1004,768,3119,182,1776,184,941,1044,2880,459,807 | 0.8703239336226946,0.032894232644399175,-0.5736061024396271,0.4673874574355663,0.5802262548677871,0.8703239336226946,1.234692175919743,0.032894232644399175,0.8703239336226946,0.8113589567569786,0.41162409949645146,2.377931653766487,0.5802262548677871,0.5802262548677871,0.8113589567569786,0.4673874574355663,0.6373161840... | 3,643 |
Activation of the mrna upon binding of the cap binding complex and eifs and subsequent binding to 43s | 27 | 52 | 2.583937 | 0.009768 | P08708,P62847,P62841,P15880,P62277,P60866,O75821,P25398,P62854,P62753,P62701,P62244,Q9UBQ5,P62241,P62081,P62857,P46782,Q04637,P11940,P62266,P62269,P55884,Q13347,P20042,P61247,P62263,Q14152 | Processes and pathways | Reactome Pathways | msigdb_reactome | 747,25,24,269,387,643,894,160,64,63,305,435,619,304,434,436,430,595,684,118,593,836,840,342,480,348,130 | 1264,886,970,894,2006,1550,1358,747,2178,684,269,342,1366,1644,160,1752,1188,1190,430,2477,836,2633,1196,1766,643,480,434,304,435,2351,348,118,593,387,1294,305,63,24,25,2032,64,436,1470,1937,595,840,130,2972,2724,1784,619,1818 | 0.3013745602323828,0.5235857910422159,0.4673874574355663,0.5235857910422159,-0.12354184408581988,0.13909345271370782,0.2468749208094238,0.637316184085691,-0.2259898614760554,0.6948631006681812,1.234692175919743,1.1111613487779155,0.2468749208094238,0.08579910129584352,1.6186732764752128,0.032894232644399175,0.356288737... | 3,643 |
Regulation of ubiquitin protein ligase activity | 9 | 15 | 2.581674 | 0.009832 | P46777,P60866,P53350,Q13257,P62081,P62841,Q12834,Q96GX5,P61927 | Processes and pathways | GO Biological process | msigdb_gobp | 125,643,588,651,434,24,180,399,178 | 738,2079,125,588,643,178,434,1090,24,1091,2777,180,651,1493,399 | 0.637316184085691,-0.174946489808922,1.8186080128566493,0.8113589567569786,0.7528747198305642,1.553221452559307,0.9897296751660267,0.41162409949645146,3.1303209321554855,0.41162409949645146,-0.6219395983652799,1.553221452559307,0.7528747198305642,0.19278333017529875,1.050187786825878 | 3,643 |
Synthesis of dna | 46 | 90 | 2.579503 | 0.009894 | Q15008,P25789,P60900,P25788,O43242,O43913,Q07864,P25205,P24941,P28066,P33991,P49720,Q99436,P62333,Q14181,Q13616,O00487,Q9UBD5,P35244,P62191,P20618,P61289,P25786,P25787,P28340,P15927,Q92530,P33992,Q9NR33,P55036,Q9H1A4,Q14997,P18858,O75832,P51530,P49736,Q13309,P35251,P51665,Q9Y619,P39748,P49643,P49642,Q13200,Q99741,P0988... | Processes and pathways | Reactome Pathways | msigdb_reactome | 537,755,644,639,510,511,768,271,518,640,521,527,939,529,182,533,884,459,54,914,299,433,428,685,687,823,495,577,1044,589,1042,238,100,340,104,583,839,101,833,807,345,830,829,352,941,982 | 1263,1913,1914,884,1347,510,511,1731,2688,340,982,1362,823,1074,100,299,518,271,428,685,639,755,1745,640,2620,1076,1184,687,2091,521,577,1079,54,1930,2475,101,1561,345,2094,1286,2190,2628,1650,829,830,527,1193,583,104,833,589,1004,644,433,914,1659,529,2777,1941,768,1481,352,839,3119,533,182,1776,238,537,1493,495,2587,9... | 0.3013745602323828,-0.07177053677304059,-0.07177053677304059,0.5235857910422159,0.2468749208094238,0.8703239336226946,0.8703239336226946,0.032894232644399175,-0.5736061024396271,1.1111613487779155,0.4673874574355663,0.2468749208094238,0.5802262548677871,0.41162409949645146,1.954875734282166,1.1726596350338454,0.8703239... | 3,643 |
WW domain [IPR001202] | 9 | 13 | 2.574089 | 0.01005 | Q8N1G2,Q96J02,Q6ZWJ1,P46939,P46940,Q13526,Q13576,O14776,Q96PU5 | Sequence | InterPro Domain | interpro_domain | 715,146,780,233,525,140,701,509,401 | 1432,509,2823,233,525,140,701,780,715,2231,856,146,401 | 0.19278333017529875,0.8703239336226946,-0.6699553268222116,1.3603994825359238,0.8703239336226946,1.7513670427695411,0.6948631006681812,0.637316184085691,0.6948631006681812,-0.2259898614760554,0.5802262548677871,1.7513670427695411,1.050187786825878 | 3,643 |
Polysome | 24 | 48 | 2.561053 | 0.010436 | P63173,P62917,P62424,Q9Y3U8,P60900,P62888,P84098,P62910,Q07020,Q06787,P62899,Q92616,P83881,P62854,P62753,P62701,P25786,P62857,Q04637,Q7Z417,Q02878,Q02543,P62266,P83731 | Localization | GO Cellular component | msigdb_gocc | 388,279,278,159,644,646,33,39,531,530,47,187,439,64,63,305,428,436,595,359,237,350,118,483 | 970,1550,3490,897,1928,1366,428,3285,827,1759,2710,644,1197,118,278,305,63,64,436,646,47,1198,39,1091,279,388,1937,483,439,33,916,350,237,595,530,531,2636,779,359,2502,1135,1877,187,1603,1234,728,1342,159 | 0.4673874574355663,0.13909345271370782,-1.569622083281108,0.5235857910422159,-0.07177053677304059,0.2468749208094238,0.9897296751660267,-1.1335470777869139,0.5802262548677871,0.032894232644399175,-0.5736061024396271,0.7528747198305642,0.356288737373063,1.8864444012100539,1.234692175919743,1.1726596350338454,2.234541210... | 3,643 |
Head and neck squamous cell carcinoma | 10 | 19 | 2.560073 | 0.010465 | P62753,Q13485,P06400,Q6R327,Q00534,P54646,P11802,Q04721,P42345,P49815 | Processes and pathways | WikiPathways | msigdb_wp | 63,254,5,444,252,303,194,351,524,117 | 2470,3309,5,1358,194,2092,3018,524,117,303,63,252,648,351,254,1485,3318,444,1129 | -0.426654247568139,-1.1783350652217268,4.54402937594712,0.2468749208094238,1.4883650140779006,-0.174946489808922,-0.8121388295267228,0.8703239336226946,1.8864444012100539,1.1726596350338454,2.234541210932711,1.2972687676797499,0.7528747198305642,1.1111613487779155,1.2972687676797499,0.19278333017529875,-1.1783350652217... | 3,643 |
Protein kinase complex | 16 | 33 | 2.552068 | 0.010709 | P51948,P24941,P54646,Q00534,P14635,O95067,P19447,P41743,P78527,P11802,P49736,P50750,Q8IUD2,Q14004,P46020,P18074 | Localization | GO Cellular component | msigdb_gocc | 274,518,303,252,124,6,427,162,165,194,583,585,106,353,78,270 | 2819,967,2170,6,1069,1926,194,1362,2086,749,2336,124,270,427,518,2838,162,78,583,585,274,3151,303,165,252,1094,353,106,3237,722,1620,2815,1344 | -0.6699553268222116,0.4673874574355663,-0.2259898614760554,4.3689581005135825,0.41162409949645146,-0.07177053677304059,1.4883650140779006,0.2468749208094238,-0.174946489808922,0.637316184085691,-0.3270137385950589,1.8186080128566493,1.234692175919743,0.9897296751660267,0.8703239336226946,-0.6699553268222116,1.618673276... | 3,643 |
Dna replication | 48 | 135 | 2.534267 | 0.011268 | Q9BTE3,Q7Z5K2,Q99543,Q14191,Q9Y3Z3,Q9NZJ0,Q7LG56,O75792,P25490,P49427,Q8WVB6,Q07864,O43913,P25205,P24941,P33991,Q96S55,Q14181,Q9UBD5,Q7L590,Q9UNS1,P35244,Q9BY42,Q29RF7,O94761,P28340,P33316,P15927,Q9Y5B9,Q96RR1,Q08945,P33992,P46063,O14757,P18858,Q13535,P51530,P49736,P39748,P50750,P35251,Q9Y619,P49643,P49642,P49916,Q9974... | Processes and pathways | GO Biological process | msigdb_gobp | 403,541,795,772,413,291,141,742,638,272,153,768,511,271,518,521,861,182,459,184,333,54,864,846,297,687,826,823,223,366,212,577,579,337,100,105,104,583,345,585,101,807,830,829,831,941,260,545 | 337,511,1731,2608,2396,2397,1736,2688,1272,742,2825,297,2403,2542,3110,3309,1069,982,2334,1362,823,3564,100,991,518,271,638,1745,687,2188,1185,1646,826,521,577,1079,54,1930,2475,101,1751,345,2094,1286,579,3518,1650,1934,272,829,830,583,831,1840,585,104,2420,2277,1004,1658,1382,2967,1472,2851,768,2636,212,2209,1771,2487... | 1.1111613487779155,0.8703239336226946,0.032894232644399175,-0.5249504103946776,-0.37700443540698164,-0.37700443540698164,0.032894232644399175,-0.5736061024396271,0.3013745602323828,0.637316184085691,-0.6699553268222116,1.1726596350338454,-0.37700443540698164,-0.4759679989713774,-0.9054161621172195,-1.1783350652217268,0... | 3,643 |
Pituitary adenoma | 11 | 15 | 2.530046 | 0.011405 | P40818,P60866,Q9UBS4,P52701,Q16658,P48735,O75874,P54277,P49815,P25490,O00170 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 907,643,38,163,1019,16,227,347,117,638,809 | 809,227,1926,638,907,997,16,117,163,347,643,2723,1019,2519,38 | 0.5802262548677871,1.3603994825359238,-0.07177053677304059,0.7528747198305642,0.5235857910422159,0.4673874574355663,3.528575244639867,1.8864444012100539,1.6186732764752128,1.1111613487779155,0.7528747198305642,-0.5736061024396271,0.4673874574355663,-0.426654247568139,2.7467559974490734 | 3,643 |
Embryo development ending in birth or egg hatching | 37 | 146 | 2.486917 | 0.012886 | Q13572,O95999,Q13485,O95067,P14635,Q9NR09,Q96EK5,Q9UNS2,Q9Y3A5,P35579,P18074,P67809,Q6R327,Q86XI2,P78527,Q9Y3I0,Q9ULH0,Q06546,P26373,Q08J23,P63167,Q14679,P62081,Q8NFG4,P42574,Q8IWS0,Q6KC79,Q9HCK8,Q99873,O95747,O14757,P20042,Q04721,P25440,Q12830,P49815,O43678 | Processes and pathways | GO Biological process | msigdb_gobp | 129,4,254,6,124,557,286,560,562,384,270,32,444,317,165,463,461,179,301,307,437,309,434,82,77,361,490,217,368,88,337,342,351,229,119,117,115 | 507,2254,337,1436,115,1543,2537,2687,2256,2258,892,2397,2822,1736,3448,6,2827,744,88,2469,4,3110,2406,3309,2831,1447,746,683,124,3362,2337,898,270,342,1928,1365,2185,229,301,688,2621,2417,1185,3018,384,906,3020,77,3553,1931,997,2190,1934,117,1379,2558,2281,2775,434,1768,437,32,165,1012,1386,351,2426,179,307,1770,119,83... | 0.8703239336226946,-0.27667722707748915,1.1111613487779155,0.19278333017529875,1.8864444012100539,0.13909345271370782,-0.4759679989713774,-0.5736061024396271,-0.27667722707748915,-0.27667722707748915,0.5235857910422159,-0.37700443540698164,-0.6699553268222116,0.032894232644399175,-1.4414863917249552,4.3689581005135825,... | 3,643 |
Translation protein SH3-like domain superfamily [IPR008991] | 7 | 11 | 2.477815 | 0.013219 | P46778,Q02878,P61254,P50914,P63241,P62917,Q5T653 | Sequence | InterPro Superfamily | interpro_homologous_superfamily | 197,237,80,431,482,279,26 | 2074,197,2022,431,80,592,279,482,237,26,3378 | -0.174946489808922,1.4883650140779006,-0.12354184408581988,0.9897296751660267,2.093521364597626,0.8113589567569786,1.234692175919743,0.9297779869287993,1.3603994825359238,3.1303209321554855,-1.2671010666360616 | 3,643 |
DNA helicase | 9 | 16 | 2.4768 | 0.013257 | O94761,Q9H4L7,P46063,Q14191,P33991,P13010,P49736,Q96RR1,P25205 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 297,404,579,772,521,749,583,366,271 | 2608,297,2086,749,271,2339,521,1079,579,583,772,1776,366,861,1804,404 | -0.5249504103946776,1.1726596350338454,-0.174946489808922,0.637316184085691,1.234692175919743,-0.3270137385950589,0.8703239336226946,0.41162409949645146,0.8113589567569786,0.8113589567569786,0.637316184085691,0.032894232644399175,1.1111613487779155,0.5802262548677871,0.032894232644399175,1.050187786825878 | 3,643 |
Damaged dna binding | 17 | 34 | 2.475371 | 0.01331 | O94761,Q14191,P19447,P52701,P13010,P09429,P54725,P28340,P39748,P29372,P15927,P27695,P20585,P35244,Q92889,P26583,P18074 | Functions | GO Molecular function | msigdb_gomf | 297,772,427,163,749,471,528,687,345,231,823,76,381,54,95,900,270 | 2397,297,471,1362,2086,749,1831,823,270,1641,427,381,1366,900,1745,76,687,231,54,906,345,997,163,2420,528,2964,2211,1205,772,1491,1498,95,1974,1975 | -0.37700443540698164,1.1726596350338454,0.9297779869287993,0.2468749208094238,-0.174946489808922,0.637316184085691,-0.019627057122083305,0.5802262548677871,1.234692175919743,0.08579910129584352,0.9897296751660267,1.050187786825878,0.2468749208094238,0.5235857910422159,0.032894232644399175,2.093521364597626,0.6948631006... | 3,643 |
Armadillo-type fold [IPR016024] | 68 | 183 | 2.467297 | 0.013614 | Q14185,Q9C0E2,Q7Z5K2,Q9BTW9,Q9UI26,Q9BVI4,Q9BTY7,Q9HCG8,Q6GYQ0,Q14999,Q13395,O60879,O43432,Q9Y263,Q5VYK3,O14981,P53618,Q6R327,Q86XI2,Q9BPX3,P78527,Q92616,P42345,Q96T76,Q8TCG1,Q6YHU6,Q9HAV4,Q7Z460,Q9HAU5,Q7Z6Z7,Q5JTH9,Q13144,Q29RF7,Q9ULT8,O75122,O75165,Q9UBF2,Q9NTI5,Q9UBQ5,Q14738,Q9H4A4,Q92845,Q9UPU5,O43747,Q04637,Q6P1X... | Sequence | InterPro Superfamily | interpro_homologous_superfamily | 131,667,541,550,149,552,287,555,284,18,139,20,739,157,393,30,759,444,317,862,165,187,524,722,854,183,328,851,728,315,849,440,846,734,420,421,877,873,619,310,868,83,623,815,595,358,429,222,821,497,490,496,571,375,114,485,238,586,105,468,335,352,354,657,117,654,548,671 | 2894,1262,964,1265,2075,2001,335,2818,811,30,1918,739,1825,815,2004,1545,468,1061,3108,891,20,420,421,1269,976,1922,2400,2401,1442,571,821,1276,2905,1365,2188,1078,3018,524,2840,429,1648,117,2025,586,2909,1375,2274,759,1086,1087,2100,1661,165,1011,2207,595,3155,1572,1574,440,352,139,105,354,131,2973,1577,485,310,2357,2... | -0.717657624490921,0.3013745602323828,0.4673874574355663,0.3013745602323828,-0.174946489808922,-0.12354184408581988,1.1111613487779155,-0.6699553268222116,0.5802262548677871,2.8984160204542766,-0.07177053677304059,0.637316184085691,-0.019627057122083305,0.5802262548677871,-0.12354184408581988,0.13909345271370782,0.9297... | 3,643 |
Cyclin a b1 b2 associated events during g2 m transition | 6 | 12 | 2.462216 | 0.013808 | P51948,P24941,P14635,O95067,Q9Y570,P63151 | Processes and pathways | Reactome Pathways | msigdb_reactome | 274,518,124,6,464,349 | 811,6,1069,124,518,2188,1078,2189,274,588,349,464 | 0.5802262548677871,4.3689581005135825,0.41162409949645146,1.8186080128566493,0.8703239336226946,-0.2259898614760554,0.41162409949645146,-0.2259898614760554,1.234692175919743,0.8113589567569786,1.1111613487779155,0.9897296751660267 | 3,643 |
Colon cancer | 6 | 16 | 2.448097 | 0.014361 | Q13485,O43684,P52701,Q8NFG4,P54277,O43683 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 254,249,163,82,347,296 | 296,249,2257,3309,1926,381,906,1752,997,163,347,254,1398,1019,82,2050 | 1.1726596350338454,1.2972687676797499,-0.27667722707748915,-1.1783350652217268,-0.07177053677304059,1.050187786825878,0.5235857910422159,0.032894232644399175,0.4673874574355663,1.6186732764752128,1.1111613487779155,1.2972687676797499,0.2468749208094238,0.4673874574355663,2.093521364597626,-0.12354184408581988 | 3,643 |
Myelodysplasia | 21 | 48 | 2.435779 | 0.01486 | P46777,O43684,P42766,Q9Y3A5,P62847,P61313,O76094,P62899,P62854,O43683,O94761,P61254,P62081,P62857,P62244,Q5F1R6,Q9NVI1,Q92889,P18077,P11766,P62263 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 125,249,15,562,25,31,514,47,64,296,297,80,434,436,435,93,219,95,341,473,348 | 296,249,2257,2259,976,514,297,3309,747,473,341,1365,1075,3285,906,3316,1752,15,3518,125,2477,2420,643,913,80,31,592,434,435,348,25,64,436,2562,47,1091,767,531,1398,93,1862,95,1804,1805,1042,219,1047,562 | 1.1726596350338454,1.2972687676797499,-0.27667722707748915,-0.27667722707748915,0.4673874574355663,0.8703239336226946,1.1726596350338454,-1.1783350652217268,0.637316184085691,0.9297779869287993,1.1111613487779155,0.2468749208094238,0.41162409949645146,-1.1335470777869139,0.5235857910422159,-1.1783350652217268,0.0328942... | 3,643 |
Ribonucleoprotein complex subunit organization | 29 | 128 | 2.433576 | 0.01495 | P46777,Q9Y3F4,P40429,O14744,P62841,Q9Y383,P63173,P41214,P78527,Q9ULC4,Q9UBB9,Q7Z478,Q9Y333,Q99590,P62750,P39023,P62857,P46782,Q96HR8,Q02878,Q13535,P20042,P27635,Q9NQ29,P62314,P62263,P83731,Q14152,Q9UKA9 | Processes and pathways | GO Biological process | msigdb_gobp | 125,412,385,378,24,158,388,161,165,190,458,314,59,206,306,196,436,430,245,237,105,342,343,122,481,348,483,130,265 | 378,1824,3276,1349,972,630,2898,3466,976,820,568,1352,2953,1065,2328,1177,2083,1180,896,2178,2179,749,2088,342,1644,343,1371,2707,1752,196,385,1188,161,2191,125,430,2963,1655,1086,1764,2910,1845,2633,1467,348,3116,481,1767,3414,306,24,436,1091,388,1382,165,483,2563,237,2038,2969,2636,1572,2778,1943,3225,1203,2918,105,2... | 1.050187786825878,-0.019627057122083305,-1.1335470777869139,0.2468749208094238,0.4673874574355663,0.7528747198305642,-0.717657624490921,-1.4844458628685837,0.4673874574355663,0.5802262548677871,0.8113589567569786,0.2468749208094238,-0.7650507386283446,0.41162409949645146,-0.3270137385950589,0.356288737373063,-0.1749464... | 3,643 |
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