term
stringlengths
2
121
overlap
int64
6
281
setsize
int64
7
499
score
float64
1.96
10.6
pval
float64
0
0.05
edge
stringlengths
41
1.97k
type
stringclasses
5 values
subtype
stringclasses
24 values
subtype_key
stringclasses
24 values
edge_idxs
stringlengths
11
1.17k
ann_idxs
stringlengths
19
2.31k
ann_vals
stringlengths
124
9.94k
sig_size
int64
2.2k
3.73k
SNF2-like, N-terminal domain superfamily [IPR038718]
7
19
2.429463
0.015121
Q9H4L7,O14981,Q9NRZ9,Q9HCK8,O14646,Q12873,Q14527
Sequence
InterPro Superfamily
interpro_homologous_superfamily
404,30,406,217,225,27,132
225,30,2608,2339,3518,1464,27,132,703,2920,391,2497,1311,1796,404,217,406,1259,962
1.3603994825359238,2.8984160204542766,-0.5249504103946776,-0.3270137385950589,-1.6955736238491228,0.19278333017529875,3.0524311894311094,1.8186080128566493,0.6948631006681812,-0.717657624490921,1.050187786825878,-0.426654247568139,0.3013745602323828,0.032894232644399175,1.050187786825878,1.4240946792303675,1.0501877868...
3,643
SNF2, N-terminal [IPR000330]
7
19
2.429463
0.015121
Q9H4L7,O14981,Q9NRZ9,Q9HCK8,O14646,Q12873,Q14527
Sequence
InterPro Domain
interpro_domain
404,30,406,217,225,27,132
225,30,2608,2339,3518,1464,27,132,703,2920,391,2497,1311,1796,404,217,406,1259,962
1.3603994825359238,2.8984160204542766,-0.5249504103946776,-0.3270137385950589,-1.6955736238491228,0.19278333017529875,3.0524311894311094,1.8186080128566493,0.6948631006681812,-0.717657624490921,1.050187786825878,-0.426654247568139,0.3013745602323828,0.032894232644399175,1.050187786825878,1.4240946792303675,1.0501877868...
3,643
Ligase activity forming carbon nitrogen bonds
11
24
2.424234
0.015341
P17812,P49915,P08243,Q14166,P50747,Q9NRF8,Q14679,Q96RQ3,P11586,P48507,O15067
Functions
GO Molecular function
msigdb_gomf
575,273,515,166,251,616,309,321,683,302,417
417,1546,1353,515,683,1278,575,1557,2184,686,903,1649,302,2629,2844,273,251,3224,166,309,1860,321,2244,616
0.9897296751660267,0.13909345271370782,0.2468749208094238,0.8703239336226946,0.6948631006681812,0.3013745602323828,0.8113589567569786,0.13909345271370782,-0.2259898614760554,0.6948631006681812,0.5235857910422159,0.08579910129584352,1.1726596350338454,-0.5249504103946776,-0.6699553268222116,1.234692175919743,1.297268767...
3,643
Abnormal thumb morphology
43
132
2.422424
0.015417
P46777,P06400,Q5H8A4,Q9Y5S9,P42766,O75369,Q8NCM8,P08708,P62847,A5YKK6,P61313,Q8N0X7,P60866,Q07020,P62899,Q93074,Q9ULP9,Q6P4I2,Q7Z6Z7,Q8N806,P62854,Q9NPF4,Q9H3S7,O94761,Q9Y4P8,Q08J23,P61254,P62244,P62857,P62081,Q15910,Q6KC79,Q9NVI1,Q93008,Q13363,Q92889,O60885,Q9BPU6,P61353,P18077,P11766,Q12830,Q9UPP1
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
125,5,777,675,15,632,22,747,25,507,31,446,643,531,47,858,50,850,315,604,64,67,867,297,625,307,80,435,436,434,845,490,219,496,700,95,567,246,592,341,473,119,805
507,1913,812,1436,3305,2168,3278,1732,567,2822,632,2398,1633,3571,297,2900,1741,3110,2007,5,747,473,341,2769,2411,989,2014,2552,2475,2959,906,3020,1752,1372,15,1648,3553,125,2477,1292,1936,2348,2911,643,1658,80,31,592,434,435,25,64,436,47,1091,2282,1384,3257,1476,531,3155,307,119,700,1485,3157,1577,1393,2113,2781,2724,...
0.8703239336226946,-0.07177053677304059,0.5802262548677871,0.19278333017529875,-1.1783350652217268,-0.2259898614760554,-1.1335470777869139,0.032894232644399175,0.8113589567569786,-0.6699553268222116,0.7528747198305642,-0.37700443540698164,0.08579910129584352,-2.0610678175841555,1.1726596350338454,-0.717657624490921,0.0...
3,643
Dna replication pre initiation
43
68
2.414524
0.015756
P56282,Q15008,P25789,P60900,P25788,O43242,O43913,Q07864,P25205,P28066,P24941,P33991,P49720,P62333,O00487,Q14181,Q9UBD5,Q7L590,P35244,P62191,P20618,P61289,P25786,P25787,P15927,Q92530,P33993,P28072,P17980,P33992,Q9NR33,P55036,Q14997,O75832,P51665,P49736,P49643,P49642,Q9Y619,Q13200,P09884,Q99741,Q99436
Processes and pathways
Reactome Pathways
msigdb_reactome
1004,537,755,644,639,510,511,768,271,640,518,521,527,529,884,182,459,184,54,914,299,433,428,685,823,495,1079,1076,1074,577,1044,589,238,340,833,583,830,829,807,352,982,941,939
1263,1913,1914,884,1347,510,511,1731,1061,2688,340,982,823,1074,299,518,271,428,685,639,755,1745,640,2620,1076,1184,521,577,1079,54,1561,2190,2628,829,830,527,1193,583,833,1375,589,1004,644,433,914,1659,529,1848,1941,768,352,3119,182,1776,2357,238,537,184,495,939,1326,941,1044,2880,459,1625,1724,807
0.3013745602323828,-0.07177053677304059,-0.07177053677304059,0.5235857910422159,0.2468749208094238,0.8703239336226946,0.8703239336226946,0.032894232644399175,0.41162409949645146,-0.5736061024396271,1.1111613487779155,0.4673874574355663,0.5802262548677871,0.41162409949645146,1.1726596350338454,0.8703239336226946,1.23469...
3,643
Protein kinase activity
33
121
2.413161
0.015815
Q9UHY1,Q00534,P25098,P33981,Q9H4A3,P24941,Q8WZ42,Q7KZI7,Q86UE8,Q9BUB5,P41743,P78527,Q9BRS2,P42345,O14733,O43683,P54646,P11802,Q9BVS4,P46020,Q99986,O95747,O60885,O75116,Q9Y4B6,O14757,P53350,Q13535,P49840,Q96Q15,P25440,Q14004,Q96GX5
Functions
GO Molecular function
msigdb_gomf
264,252,12,520,171,518,169,445,316,451,162,165,323,524,53,296,303,194,216,78,500,88,567,87,114,337,588,105,584,548,229,353,399
53,337,3358,2461,2819,1435,810,965,967,1917,3305,296,2257,567,87,816,2170,3571,1353,88,1636,1637,1069,3283,3412,1450,2334,3311,194,3467,3362,2337,1642,987,518,12,229,993,686,688,2621,2092,520,1080,162,524,78,1081,998,2419,1288,584,641,585,3189,3317,588,3151,303,1092,1382,165,252,1094,1386,3224,2107,2353,1667,1298,1850,...
2.377931653766487,1.1111613487779155,-1.2671010666360616,-0.426654247568139,-0.6699553268222116,0.19278333017529875,0.5802262548677871,0.4673874574355663,0.4673874574355663,-0.07177053677304059,-1.1783350652217268,1.1726596350338454,-0.27667722707748915,0.8113589567569786,2.0239015433854965,0.5802262548677871,-0.225989...
3,643
Aplasia hypoplasia involving forearm bones
9
23
2.397945
0.016487
O94761,Q9Y5S9,P61254,Q13535,Q14999,Q6KC79,Q8NCM8,Q9NVI1,Q92889
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
297,675,80,105,18,490,22,219,95
3179,632,3571,297,1926,906,3020,1752,80,2034,105,18,2431,490,22,95,3030,2798,1804,1805,219,1722,675
-0.997521253539814,0.7528747198305642,-2.0610678175841555,1.1726596350338454,-0.07177053677304059,0.5235857910422159,-0.8121388295267228,0.032894232644399175,2.093521364597626,-0.12354184408581988,1.954875734282166,3.528575244639867,-0.37700443540698164,0.9297779869287993,3.2087982428782533,2.0239015433854965,-0.812138...
3,643
Cyclin a cdk2 associated events at s phase entry
25
46
2.392266
0.016745
P06400,Q15008,P25789,P60900,P25788,O43242,P51948,P28066,P24941,P49720,P62333,O00487,Q13616,P20618,P61289,P25786,P25787,P11802,Q92530,P55036,Q13309,O75832,P51665,Q13200,Q99436
Processes and pathways
Reactome Pathways
msigdb_reactome
5,537,755,644,639,510,274,640,518,527,529,884,533,299,433,428,685,194,495,589,839,340,833,352,939
1263,1913,1914,884,1347,510,340,5,194,1074,299,518,428,685,639,755,640,2620,1076,1184,2092,1561,2190,2628,527,1193,833,274,589,644,433,914,1659,529,2777,1941,2209,352,839,533,537,495,939,1326,1625,1724
0.3013745602323828,-0.07177053677304059,-0.07177053677304059,0.5235857910422159,0.2468749208094238,0.8703239336226946,1.1111613487779155,4.54402937594712,1.4883650140779006,0.41162409949645146,1.1726596350338454,0.8703239336226946,0.9897296751660267,0.6948631006681812,0.7528747198305642,0.637316184085691,0.752874719830...
3,643
Lagging strand synthesis
9
19
2.388884
0.0169
P18858,Q14181,P51530,P28340,P39748,P35251,P15927,P49643,P35244
Processes and pathways
Reactome Pathways
msigdb_reactome
100,182,104,687,345,101,823,830,54
982,1362,823,100,1745,687,54,1930,2475,101,345,2094,1286,1650,829,830,104,182,3205
0.4673874574355663,0.2468749208094238,0.5802262548677871,1.954875734282166,0.032894232644399175,0.6948631006681812,2.377931653766487,-0.07177053677304059,-0.426654247568139,1.954875734282166,1.1111613487779155,-0.174946489808922,0.3013745602323828,0.08579910129584352,0.5802262548677871,0.5802262548677871,1.954875734282...
3,643
CMGC group
13
18
2.387785
0.01695
P49841,P24941,P06493,Q00534,P19784,P67870,P11802,P49840,P28482,P50750,Q14004,P27361,Q96SB4
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
641,518,1069,252,987,1092,194,584,688,585,353,993,1142
1069,194,987,518,993,688,1288,584,641,585,1092,1382,252,1094,2354,353,1673,1142
0.41162409949645146,1.4883650140779006,0.4673874574355663,0.8703239336226946,0.4673874574355663,0.6948631006681812,0.3013745602323828,0.8113589567569786,0.7528747198305642,0.8113589567569786,0.41162409949645146,0.2468749208094238,1.2972687676797499,0.41162409949645146,-0.3270137385950589,1.1111613487779155,0.0857991012...
3,643
HECT, E3 ligase catalytic domain [IPR035983]
6
12
2.380027
0.017311
Q5GLZ8,O95071,Q15386,Q96J02,Q7Z6Z7,Q96PU5
Sequence
InterPro Superfamily
interpro_homologous_superfamily
357,424,256,146,315,401
424,1274,1200,1577,256,357,1781,315,146,401,1163,734
0.9897296751660267,0.3013745602323828,0.356288737373063,0.13909345271370782,1.2972687676797499,1.1111613487779155,0.032894232644399175,1.1726596350338454,1.7513670427695411,1.050187786825878,0.41162409949645146,0.6948631006681812
3,643
HECT domain [IPR000569]
6
12
2.380027
0.017311
Q5GLZ8,O95071,Q15386,Q96J02,Q7Z6Z7,Q96PU5
Sequence
InterPro Domain
interpro_domain
357,424,256,146,315,401
424,1274,1200,1577,256,357,1781,315,146,401,1163,734
0.9897296751660267,0.3013745602323828,0.356288737373063,0.13909345271370782,1.2972687676797499,1.1111613487779155,0.032894232644399175,1.1726596350338454,1.7513670427695411,1.050187786825878,0.41162409949645146,0.6948631006681812
3,643
Mismatch repair
7
12
2.370847
0.017747
P52701,P18858,P09429,O75792,P20585,P54277,P35244
Processes and pathways
GO Biological process
msigdb_gobp
163,100,471,742,381,347,54
742,471,1362,823,100,381,1745,54,997,163,347,2387
0.637316184085691,0.9297779869287993,0.2468749208094238,0.5802262548677871,1.954875734282166,1.050187786825878,0.032894232644399175,2.377931653766487,0.4673874574355663,1.6186732764752128,1.1111613487779155,-0.3270137385950589
3,643
Dna repair pathways full network
34
59
2.367633
0.017902
Q9Y620,Q14191,P13010,P43246,O94782,P20585,Q07864,P18074,P51948,P52701,P78527,P54725,P41208,P35244,P38398,P09874,Q8TAF3,P19447,Q9UGN5,P28340,Q16658,P15927,P27695,Q9NVI1,Q92889,Q9NR33,O14757,P18858,Q13535,P09429,P39748,P35251,P49916,P29372
Processes and pathways
WikiPathways
msigdb_wp
962,772,749,997,380,381,768,270,274,163,165,528,523,54,906,298,203,427,620,687,1019,823,76,219,95,1044,337,100,105,471,345,101,831,231
337,2397,380,471,298,1362,2086,749,1831,823,270,100,1641,427,381,1745,76,687,231,2838,54,1930,2475,101,906,345,2094,1286,523,997,1650,831,1840,274,163,528,2964,1004,165,768,3432,105,1205,772,1491,1019,203,1694,95,1975,1804,1805,1044,2880,219,620,2387,3205,962
1.1111613487779155,-0.37700443540698164,1.050187786825878,0.9297779869287993,1.1726596350338454,0.2468749208094238,-0.174946489808922,0.637316184085691,-0.019627057122083305,0.5802262548677871,1.234692175919743,1.954875734282166,0.08579910129584352,0.9897296751660267,1.050187786825878,0.032894232644399175,2.09352136459...
3,643
Small for gestational age
37
93
2.365718
0.017995
P46777,Q13485,Q14999,P42766,Q9Y3A5,P08708,P62847,P25490,A5YKK6,P61313,P18074,P60866,Q07020,P62899,Q93074,Q9UET6,Q7Z6Z7,P62854,O94761,Q9Y584,P29084,Q08J23,P61254,P62244,P62081,P62857,Q8NFG4,Q5F1R6,Q93008,Q13363,P51570,P61353,P18077,P49711,Q6PGP7,Q9Y619,P50570
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
125,254,18,15,562,747,25,638,507,31,270,643,531,47,858,460,315,64,297,737,61,307,80,435,434,436,82,93,496,700,587,592,341,103,120,807,478
507,1265,2256,2257,1633,297,2900,3282,2007,2176,2701,747,1926,2835,270,341,2771,638,61,995,1456,2959,1187,1751,1752,2095,1188,15,2192,125,2477,1374,103,3188,478,587,3061,832,3317,2420,2197,643,913,80,31,592,434,435,25,64,436,47,1091,531,307,700,3119,254,2039,18,1103,1107,93,1497,3230,850,120,2497,315,3575,3161,82,2501,...
0.8703239336226946,0.3013745602323828,-0.27667722707748915,-0.27667722707748915,0.08579910129584352,1.1726596350338454,-0.717657624490921,-1.1335470777869139,-0.12354184408581988,-0.2259898614760554,-0.5736061024396271,0.637316184085691,-0.07177053677304059,-0.6699553268222116,1.234692175919743,1.1111613487779155,-0.62...
3,643
Translation regulator activity
36
82
2.362658
0.018144
Q9Y450,Q9BY44,O43432,P13639,Q8NE71,O75821,P41214,Q92905,O15371,Q06787,Q9ULC4,Q92616,Q7Z478,P35268,Q13144,O60841,Q7L576,Q9UBQ5,P04818,Q04637,P11940,P62495,Q05639,P41567,P00374,P55884,P63241,P34896,Q13347,P20042,P49770,Q6PKG0,P27635,P62263,Q9UI10,Q14152
Functions
GO Molecular function
msigdb_gomf
959,288,739,897,447,894,161,717,886,530,190,187,314,904,440,173,599,619,682,595,684,594,698,90,89,836,482,475,840,342,234,779,343,348,804,130
1997,1264,2166,886,970,739,972,1826,173,894,2006,89,682,1550,1358,684,897,1182,1642,342,1644,2013,1183,343,1558,475,2552,904,3020,1188,161,90,2343,1932,1190,2345,1568,234,1759,2710,1086,836,2633,1196,1766,348,594,482,1661,2967,595,698,530,440,840,2108,130,1774,919,2972,2724,1496,779,1784,599,1862,314,447,187,1878,717,1...
-0.12354184408581988,0.3013745602323828,-0.2259898614760554,0.5235857910422159,0.4673874574355663,0.637316184085691,0.4673874574355663,-0.019627057122083305,1.553221452559307,0.5235857910422159,-0.12354184408581988,2.0239015433854965,0.6948631006681812,0.13909345271370782,0.2468749208094238,0.6948631006681812,0.5235857...
3,643
Negative regulation of cell cycle g1 s phase transition
7
17
2.35248
0.018649
P06400,P61254,P78527,Q9Y3I1,Q13642,Q7Z7L1,Q8N6R0
Processes and pathways
GO Biological process
msigdb_gobp
5,80,165,221,534,260,261
1432,3309,5,823,518,902,80,165,534,845,1498,3075,2364,260,2120,261,221
0.19278333017529875,-1.1783350652217268,4.54402937594712,0.5802262548677871,0.8703239336226946,0.5235857910422159,2.093521364597626,1.6186732764752128,0.8703239336226946,0.5802262548677871,0.19278333017529875,-0.8589259728879383,-0.3270137385950589,1.2972687676797499,-0.174946489808922,1.2972687676797499,1.424094679230...
3,643
Hypomimic face
6
15
2.348077
0.018871
O75165,Q9Y3I1,Q7LG56,Q96RR1,Q9Y263,Q15043
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
421,221,141,366,157,65
1173,421,3308,1927,1456,2563,595,65,1680,2364,141,1797,366,157,221
0.356288737373063,0.9897296751660267,-1.1783350652217268,-0.07177053677304059,0.19278333017529875,-0.4759679989713774,0.8113589567569786,2.234541210932711,0.08579910129584352,-0.3270137385950589,1.7513670427695411,0.032894232644399175,1.1111613487779155,1.6847219694542854,1.4240946792303675
3,643
G13 signaling pathway
9
16
2.333624
0.019615
P61586,O75116,O60610,P07737,P46940,Q92888,P63000,Q13576,Q7L576
Processes and pathways
WikiPathways
msigdb_wp
645,87,468,746,525,262,763,701,599
468,87,746,1367,525,1658,645,2350,763,1947,701,2780,1581,599,262,957
0.9297779869287993,2.0239015433854965,0.637316184085691,0.2468749208094238,0.8703239336226946,0.08579910129584352,0.7528747198305642,-0.3270137385950589,0.637316184085691,-0.07177053677304059,0.6948631006681812,-0.6219395983652799,0.13909345271370782,0.8113589567569786,1.2972687676797499,0.5235857910422159
3,643
Regulation of cyclin dependent protein kinase activity
14
23
2.327682
0.019929
P08238,P51948,O95067,P14635,O00410,Q96JB5,P53350,O75832,P49736,Q9Y3I1,Q16543,P42574,Q99741,O95373
Processes and pathways
GO Biological process
msigdb_gobp
896,274,6,124,964,720,588,340,583,221,1018,77,941,571
964,340,2170,6,571,896,3467,124,2189,2838,77,583,274,588,2420,1383,1018,720,941,1886,1620,1163,221
0.4673874574355663,1.1111613487779155,-0.2259898614760554,4.3689581005135825,0.8113589567569786,0.5235857910422159,-1.4844458628685837,1.8186080128566493,-0.2259898614760554,-0.6699553268222116,2.093521364597626,0.8113589567569786,1.234692175919743,0.8113589567569786,-0.37700443540698164,0.2468749208094238,0.4673874574...
3,643
Spindle localization
11
22
2.315092
0.020608
O75122,Q14204,Q13257,P53350,P61160,Q14203,P35579,Q7Z460,P27816,Q15334,P43034
Processes and pathways
GO Biological process
msigdb_gobp
420,308,651,588,432,536,384,851,994,924,909
2002,420,2831,1367,994,384,1648,909,588,1846,432,651,536,308,1777,2357,1778,924,851,1139,2139,2070
-0.12354184408581988,0.9897296751660267,-0.6699553268222116,0.2468749208094238,0.4673874574355663,1.050187786825878,0.08579910129584352,0.5235857910422159,0.8113589567569786,-0.019627057122083305,0.9897296751660267,0.7528747198305642,0.8703239336226946,1.1726596350338454,0.032894232644399175,-0.3270137385950589,0.03289...
3,643
Squamous cell carcinoma
11
19
2.315038
0.020611
O94761,Q9H4L7,P29084,O60885,Q14191,P19447,Q9BUR4,Q9H1A4,Q03426,Q92889,P18074
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
297,404,61,567,772,427,41,1042,918,95,270
2259,567,297,3333,1639,270,427,992,61,1753,2195,2420,918,772,1681,95,41,1042,404
-0.27667722707748915,0.8113589567569786,1.1726596350338454,-1.2228519251976793,0.08579910129584352,1.234692175919743,0.9897296751660267,0.4673874574355663,2.234541210932711,0.032894232644399175,-0.2259898614760554,-0.37700443540698164,0.5235857910422159,0.637316184085691,0.08579910129584352,2.0239015433854965,2.6718102...
3,643
Neddylation
38
81
2.310567
0.020857
Q8TEB1,Q14999,Q9NZJ0,Q9UNS2,Q15008,P25789,P60900,O94888,P25788,O43242,P28066,P61962,Q96ME1,P49720,Q92905,P62333,O00487,Q13616,Q93034,Q86X83,Q15345,P20618,P61289,P25786,Q13564,P25787,Q9Y3I1,Q7L5N1,Q92530,P55036,Q14997,O75832,Q13309,P51665,Q8TBC4,Q13200,Q99436,Q86VP6
Processes and pathways
Reactome Pathways
msigdb_reactome
8,18,291,560,537,755,644,267,639,510,640,277,721,527,717,529,884,533,857,185,441,299,433,428,199,685,221,491,495,589,238,340,839,833,661,352,939,657
1263,1913,1914,884,1347,510,2897,340,267,1074,299,428,685,639,755,640,2620,1076,1184,1561,2190,2628,527,1193,833,589,644,1006,2281,433,277,2422,914,1659,529,2777,1941,1482,352,839,199,533,1099,1485,1205,3318,238,18,537,1672,441,1397,1106,1491,2114,1858,491,657,185,1221,661,8,495,717,857,721,939,1326,2667,1040,1883,3034...
0.3013745602323828,-0.07177053677304059,-0.07177053677304059,0.5235857910422159,0.2468749208094238,0.8703239336226946,-0.717657624490921,1.1111613487779155,1.234692175919743,0.41162409949645146,1.1726596350338454,0.9897296751660267,0.6948631006681812,0.7528747198305642,0.637316184085691,0.7528747198305642,-0.5249504103...
3,643
GTPase-activating protein
7
20
2.301302
0.021375
O60343,Q13017,Q07960,Q6GYQ0,Q9ULP9,P49815,Q4KMP7
Functions
Panther Protein class
panther_protein_class
512,128,36,284,50,117,392
512,1365,1565,525,117,36,128,701,1394,392,2785,284,2582,3485,2048,1131,2243,2598,50,1820
0.8703239336226946,0.2468749208094238,0.13909345271370782,0.8703239336226946,1.8864444012100539,2.7467559974490734,1.8186080128566493,0.6948631006681812,0.2468749208094238,1.050187786825878,-0.6219395983652799,1.234692175919743,-0.4759679989713774,-1.5271567640193044,-0.12354184408581988,0.41162409949645146,-0.22598986...
3,643
Dynein complex
6
13
2.299
0.021505
Q14204,P63167,O43237,Q14203,Q8IVD9,Q8NCM8
Localization
GO Cellular component
msigdb_gocc
308,437,226,536,658,22
226,637,437,1576,2284,536,308,658,22,1140,3086,1624,1431
1.3603994825359238,0.7528747198305642,0.9897296751660267,0.13909345271370782,-0.27667722707748915,0.8703239336226946,1.1726596350338454,0.7528747198305642,3.2087982428782533,0.41162409949645146,-0.8589259728879383,0.13909345271370782,0.2468749208094238
3,643
Activation of atr in response to replication stress
14
27
2.289173
0.022069
P33992,P24941,P25205,P33991,O14757,Q13535,P49736,Q9UBD5,P15927,Q9Y619,Q7L590,Q99741,P35244,O43913
Processes and pathways
Reactome Pathways
msigdb_reactome
577,518,271,521,337,105,583,459,823,807,184,941,54,511
337,511,1731,892,2688,823,518,271,1745,2189,521,577,1079,54,1930,2475,2094,1286,583,3119,105,1776,184,941,2941,459,807
1.1111613487779155,0.8703239336226946,0.032894232644399175,0.5235857910422159,-0.5736061024396271,0.5802262548677871,0.8703239336226946,1.234692175919743,0.032894232644399175,-0.2259898614760554,0.8703239336226946,0.8113589567569786,0.41162409949645146,2.377931653766487,-0.07177053677304059,-0.426654247568139,-0.174946...
3,643
Deoxyribonuclease activity
6
21
2.280753
0.022563
Q66K74,P51530,P28340,P39748,P27695,Q92889
Functions
GO Molecular function
msigdb_gomf
443,104,687,345,76,95
2003,1353,1279,1641,1366,76,687,345,1840,104,768,1206,1019,443,1120,1869,1694,95,2248,1900,2387
-0.12354184408581988,0.2468749208094238,0.3013745602323828,0.08579910129584352,0.2468749208094238,2.093521364597626,0.6948631006681812,1.1111613487779155,-0.019627057122083305,1.954875734282166,0.637316184085691,0.356288737373063,0.4673874574355663,0.9897296751660267,0.41162409949645146,-0.019627057122083305,0.08579910...
3,643
Papain-like cysteine peptidase superfamily [IPR038765]
15
28
2.278802
0.022679
P17655,P40818,P54578,Q96FW1,Q9Y4P1,Q9GZR1,Q9UPU5,O94782,Q14694,Q86UV5,Q01804,Q13867,Q93008,Q9P275,Q9Y4E8
Sequence
InterPro Superfamily
interpro_homologous_superfamily
898,907,642,719,414,452,623,380,920,360,917,535,496,803,29
1542,380,2541,2331,898,907,1460,912,642,917,535,920,2042,360,2796,3029,496,1696,719,2053,1325,452,1713,803,623,29,414,1538
0.13909345271370782,1.050187786825878,-0.4759679989713774,-0.3270137385950589,0.5235857910422159,0.5235857910422159,0.19278333017529875,0.5235857910422159,0.7528747198305642,0.5235857910422159,0.8703239336226946,0.5235857910422159,-0.12354184408581988,1.1111613487779155,-0.6219395983652799,-0.8121388295267228,0.9297779...
3,643
DNA helicase
8
15
2.277381
0.022763
O94761,Q9H4L7,P46063,P19447,Q14191,P13010,Q96RR1,P18074
Functions
Panther Protein class
panther_protein_class
297,404,579,427,772,749,366,270
2608,297,2086,749,270,427,2339,579,1464,2420,772,366,861,1804,404
-0.5249504103946776,1.1726596350338454,-0.174946489808922,0.637316184085691,1.234692175919743,0.9897296751660267,-0.3270137385950589,0.8113589567569786,0.19278333017529875,-0.37700443540698164,0.637316184085691,1.1111613487779155,0.5802262548677871,0.032894232644399175,1.050187786825878
3,643
Orc1 removal from chromatin
31
54
2.274353
0.022945
Q15008,P25789,P60900,P25788,O43242,O43913,P25205,P28066,P24941,P33991,P49720,P62333,O00487,Q13616,Q9UBD5,P20618,P61289,P25786,P25787,Q92530,P33992,P55036,Q13309,Q14997,O75832,P51665,P49736,Q9Y619,Q13200,Q99741,Q99436
Processes and pathways
Reactome Pathways
msigdb_reactome
537,755,644,639,510,511,271,640,518,521,527,529,884,533,459,299,433,428,685,495,577,589,839,238,340,833,583,807,352,941,939
1263,1913,1914,884,1347,510,511,1731,340,1074,299,518,271,428,685,639,755,640,2620,1076,1184,521,577,1079,1561,2190,2628,527,1193,583,833,589,644,433,914,1659,529,2777,1941,352,839,3119,533,1776,238,537,495,939,1326,941,459,1625,1724,807
0.3013745602323828,-0.07177053677304059,-0.07177053677304059,0.5235857910422159,0.2468749208094238,0.8703239336226946,0.8703239336226946,0.032894232644399175,1.1111613487779155,0.41162409949645146,1.1726596350338454,0.8703239336226946,1.234692175919743,0.9897296751660267,0.6948631006681812,0.7528747198305642,0.63731618...
3,643
Abnormality of the musculature of the hand
16
37
2.268552
0.023296
P46777,P61254,Q07020,Q96IJ6,P62081,P62857,P62899,P62244,P42766,Q8TD16,Q14203,P61353,P18077,P62847,P62854,P61313
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
125,80,531,320,434,436,47,435,15,186,536,592,341,25,64,31
3305,2258,2827,2698,747,3413,341,989,3254,1752,2096,15,125,2477,1764,643,80,31,592,434,435,25,64,436,47,1091,531,1772,536,1487,3290,1218,3125,186,320,2246,1910
-1.1783350652217268,-0.27667722707748915,-0.6699553268222116,-0.5736061024396271,0.637316184085691,-1.3548095072485222,1.1111613487779155,0.4673874574355663,-1.0884844874787485,0.032894232644399175,-0.174946489808922,3.528575244639867,1.8186080128566493,-0.426654247568139,0.032894232644399175,0.7528747198305642,2.09352...
3,643
Processive synthesis on the lagging strand
8
14
2.262748
0.023651
P18858,Q14181,P51530,P28340,P39748,P49643,P15927,P35244
Processes and pathways
Reactome Pathways
msigdb_reactome
100,182,104,687,345,830,823,54
982,1362,823,100,1745,687,54,345,1650,829,830,104,182,3205
0.4673874574355663,0.2468749208094238,0.5802262548677871,1.954875734282166,0.032894232644399175,0.6948631006681812,2.377931653766487,1.1111613487779155,0.08579910129584352,0.5802262548677871,0.5802262548677871,1.954875734282166,1.553221452559307,-0.997521253539814
3,643
Base excision repair
11
19
2.256738
0.024024
P09874,Q9NR33,Q9UGN5,P18858,P09429,P28340,P39748,P49916,P29372,P27695,Q07864
Processes and pathways
WikiPathways
msigdb_wp
298,1044,620,100,471,687,345,831,231,76,768
471,298,1362,1831,100,1641,76,687,231,345,1650,831,1004,768,1975,1044,2880,620,3205
0.9297779869287993,1.1726596350338454,0.2468749208094238,-0.019627057122083305,1.954875734282166,0.08579910129584352,2.093521364597626,0.6948631006681812,1.3603994825359238,1.1111613487779155,0.08579910129584352,0.5802262548677871,0.4673874574355663,0.637316184085691,-0.07177053677304059,0.4673874574355663,-0.669955326...
3,643
Onecarbon metabolism
7
17
2.251106
0.024379
P00374,P23526,P26358,P34896,P04818,P11586,P13995
Processes and pathways
WikiPathways
msigdb_wp
89,516,60,475,682,683,474
89,682,683,474,1557,516,60,996,475,2552,692,1931,2844,1860,1703,1421,1338
2.0239015433854965,0.6948631006681812,0.6948631006681812,0.9297779869287993,0.13909345271370782,0.8703239336226946,2.234541210932711,0.4673874574355663,0.9297779869287993,-0.4759679989713774,0.6948631006681812,-0.07177053677304059,-0.6699553268222116,-0.019627057122083305,0.08579910129584352,0.2468749208094238,0.301374...
3,643
Ribosomal small subunit assembly
7
12
2.242786
0.024911
P62857,P78527,P46782,P62263,P63173,O75616,P62841
Processes and pathways
GO Biological process
msigdb_gobp
436,165,430,348,388,568,24
568,2178,749,1752,430,348,24,436,388,165,3122,2604
0.8113589567569786,-0.2259898614760554,0.637316184085691,0.032894232644399175,0.9897296751660267,1.1111613487779155,3.1303209321554855,0.9897296751660267,1.050187786825878,1.6186732764752128,-0.9054161621172195,-0.4759679989713774
3,643
Resolution of abasic sites ap sites
13
28
2.241585
0.024988
P09874,Q9NR33,Q9UGN5,P18858,P28340,P49916,P39748,P15927,P27695,P35251,P29372,P35244,Q07864
Processes and pathways
Reactome Pathways
msigdb_reactome
298,1044,620,100,687,831,345,823,76,101,231,54,768
298,1362,1831,823,100,1641,1745,76,687,231,54,1930,2475,101,345,2094,1286,1650,831,1004,768,1867,1975,1044,2880,1335,620,3205
1.1726596350338454,0.2468749208094238,-0.019627057122083305,0.5802262548677871,1.954875734282166,0.08579910129584352,0.032894232644399175,2.093521364597626,0.6948631006681812,1.3603994825359238,2.377931653766487,-0.07177053677304059,-0.426654247568139,1.954875734282166,1.1111613487779155,-0.174946489808922,0.3013745602...
3,643
Translation regulator activity nucleic acid binding
33
66
2.235523
0.025383
Q9Y450,Q9BY44,O43432,P13639,Q8NE71,O75821,P41214,Q92905,O15371,Q9ULC4,Q92616,Q7Z478,Q14232,Q13144,O60841,Q9UBQ5,P04818,Q04637,P11940,P62495,Q05639,P41567,P00374,P55884,P34896,Q13347,P20042,P49770,Q6PKG0,P63241,Q9UI10,Q14152,O43583
Functions
GO Molecular function
msigdb_gomf
959,288,739,897,447,894,161,717,886,190,187,314,919,440,173,619,682,595,684,594,698,90,89,836,475,840,342,234,779,482,804,130,972
1997,1264,886,970,739,972,1826,173,894,2006,89,682,1550,1358,684,897,1182,342,1644,2013,1183,1558,475,2552,1188,161,90,2343,1932,2345,234,1086,836,2633,1196,1766,594,482,1661,2967,595,698,440,840,130,1774,919,2972,2724,779,1784,1862,314,447,187,1878,717,1701,288,1521,1249,619,804,190,1818,959
-0.12354184408581988,0.3013745602323828,0.5235857910422159,0.4673874574355663,0.637316184085691,0.4673874574355663,-0.019627057122083305,1.553221452559307,0.5235857910422159,-0.12354184408581988,2.0239015433854965,0.6948631006681812,0.13909345271370782,0.2468749208094238,0.6948631006681812,0.5235857910422159,0.35628873...
3,643
Small ribosomal subunit
22
50
2.23525
0.025401
Q9NVS2,Q9BY44,P62841,O60783,P62847,P15880,P62277,P25398,Q7Z478,P63244,P62854,P62753,P62701,P62244,P62081,P62241,P62857,P46782,P62266,P62269,P61247,P62263
Localization
GO Cellular component
msigdb_gocc
148,288,24,631,25,269,387,160,314,438,64,63,305,435,434,304,436,430,118,593,480,348
631,1550,747,2178,269,1366,160,1752,1190,430,2477,3150,643,480,434,304,435,2351,348,118,593,387,1294,305,63,24,25,2032,64,436,1937,438,3191,1939,3395,1662,1570,2966,3117,314,2583,288,148,3465,2319,2604,1819,1167,1052,2165
0.7528747198305642,0.13909345271370782,0.637316184085691,-0.2259898614760554,1.234692175919743,0.2468749208094238,1.6186732764752128,0.032894232644399175,0.356288737373063,0.9897296751660267,-0.426654247568139,-0.9516133105392405,0.7528747198305642,0.9297779869287993,0.9897296751660267,1.1726596350338454,0.989729675166...
3,643
Nucleotide metabolism
8
13
2.233491
0.025517
P19623,P00374,P28340,P13995,Q7LG56,P30520,P09884,P00492
Processes and pathways
WikiPathways
msigdb_wp
825,89,687,474,141,903,982,980
89,980,982,474,825,1643,991,687,903,2015,1185,1468,141
2.0239015433854965,0.4673874574355663,0.4673874574355663,0.9297779869287993,0.5802262548677871,0.08579910129584352,0.4673874574355663,0.6948631006681812,0.5235857910422159,-0.12354184408581988,0.356288737373063,0.19278333017529875,1.7513670427695411
3,643
Metabolism of polyamines
21
39
2.232946
0.025553
Q15008,P25789,P60900,P25788,O43242,P28066,P49720,P62333,O00487,P20618,P61289,P25786,P25787,Q92530,P19623,P55036,Q14997,O75832,P51665,Q13200,Q99436
Processes and pathways
Reactome Pathways
msigdb_reactome
537,755,644,639,510,640,527,529,884,299,433,428,685,495,825,589,238,340,833,352,939
1263,1913,1914,884,1347,510,340,1074,825,299,428,685,639,755,640,2620,1076,1184,1561,2190,2628,527,1193,833,589,644,433,914,1659,529,1941,352,238,537,495,939,1326,1625,1724
0.3013745602323828,-0.07177053677304059,-0.07177053677304059,0.5235857910422159,0.2468749208094238,0.8703239336226946,1.1111613487779155,0.41162409949645146,0.5802262548677871,1.1726596350338454,0.9897296751660267,0.6948631006681812,0.7528747198305642,0.637316184085691,0.7528747198305642,-0.5249504103946776,0.411624099...
3,643
Dna strand elongation
13
29
2.228317
0.025859
P33992,P33991,P18858,Q14181,P51530,P28340,P49736,P39748,P15927,P35251,P49643,P35244,P25205
Processes and pathways
Reactome Pathways
msigdb_reactome
577,521,100,182,104,687,583,345,823,101,830,54,271
2688,982,1362,823,100,271,1745,687,521,577,1079,54,1930,2475,101,345,2094,1286,1650,829,830,583,104,182,1776,1238,2131,2603,3205
-0.5736061024396271,0.4673874574355663,0.2468749208094238,0.5802262548677871,1.954875734282166,1.234692175919743,0.032894232644399175,0.6948631006681812,0.8703239336226946,0.8113589567569786,0.41162409949645146,2.377931653766487,-0.07177053677304059,-0.426654247568139,1.954875734282166,1.1111613487779155,-0.17494648980...
3,643
Resolution of ap sites via the multiple nucleotide patch replacement pathway
11
23
2.227833
0.025892
P09874,Q9NR33,Q9UGN5,P18858,P28340,P39748,P35251,P15927,P27695,P35244,Q07864
Processes and pathways
Reactome Pathways
msigdb_reactome
298,1044,620,100,687,345,101,823,76,54,768
298,1362,823,100,1745,76,687,54,1930,2475,101,345,2094,1286,1650,1004,768,1867,1044,2880,1335,620,3205
1.1726596350338454,0.2468749208094238,0.5802262548677871,1.954875734282166,0.032894232644399175,2.093521364597626,0.6948631006681812,2.377931653766487,-0.07177053677304059,-0.426654247568139,1.954875734282166,1.1111613487779155,-0.174946489808922,0.3013745602323828,0.08579910129584352,0.4673874574355663,0.6373161840856...
3,643
Homologous dna pairing and strand exchange
8
22
2.223997
0.026149
Q14191,O14757,Q13535,P51530,O60921,P15927,P35244,Q92547
Processes and pathways
Reactome Pathways
msigdb_reactome
772,337,105,104,892,823,54,545
337,2003,892,2397,823,1745,54,1930,2475,906,2094,1286,1840,104,2420,105,772,545,1694,2590,1804,2387
1.1111613487779155,-0.12354184408581988,0.5235857910422159,-0.37700443540698164,0.5802262548677871,0.032894232644399175,2.377931653766487,-0.07177053677304059,-0.426654247568139,0.5235857910422159,-0.174946489808922,0.3013745602323828,-0.019627057122083305,1.954875734282166,-0.37700443540698164,1.954875734282166,0.6373...
3,643
Translation initiation factor activity
21
40
2.223441
0.026186
Q9BY44,O43432,O75821,P41214,Q92905,O15371,Q9ULC4,Q7Z478,Q14232,Q13144,O60841,Q9UBQ5,Q04637,P41567,P55884,Q13347,P20042,P49770,Q9UI10,Q14152,O43583
Functions
GO Molecular function
msigdb_gomf
288,739,894,161,717,886,190,314,919,440,173,619,595,90,836,840,342,234,804,130,972
1264,886,970,739,972,1826,173,894,2006,1550,1358,342,1644,1188,161,90,1932,234,1086,836,2633,1196,1766,1661,595,440,840,130,919,2972,2724,1784,314,717,288,1249,619,804,190,1818
0.3013745602323828,0.5235857910422159,0.4673874574355663,0.637316184085691,0.4673874574355663,-0.019627057122083305,1.553221452559307,0.5235857910422159,-0.12354184408581988,0.13909345271370782,0.2468749208094238,1.1111613487779155,0.08579910129584352,0.356288737373063,1.6186732764752128,2.0239015433854965,-0.071770536...
3,643
Protein k48 linked ubiquitination
6
14
2.219832
0.02643
O95071,Q8TDB6,Q15386,Q96J02,P49427,Q96PU5
Processes and pathways
GO Biological process
msigdb_gobp
424,40,256,146,272,401
424,1066,272,2278,2713,2777,1200,839,533,1485,256,40,146,401
0.9897296751660267,0.41162409949645146,1.234692175919743,-0.27667722707748915,-0.5736061024396271,-0.6219395983652799,0.356288737373063,0.5802262548677871,0.8703239336226946,0.19278333017529875,1.2972687676797499,2.6718102012330496,1.7513670427695411,1.050187786825878
3,643
Endoribonuclease activity
9
25
2.216917
0.026629
Q9ULX3,Q9BQG2,O75818,Q96DE0,Q99575,P39748,P27695,Q96F86,Q9UK59
Functions
GO Molecular function
msigdb_gomf
506,170,339,46,322,345,76,608,374
3425,1916,742,339,76,345,2275,1381,1206,2117,1308,46,608,322,1233,612,170,1977,2745,374,2752,506,1900,2387,2891
-1.3982753068059497,-0.07177053677304059,0.637316184085691,1.1111613487779155,2.093521364597626,1.1111613487779155,-0.27667722707748915,0.2468749208094238,0.356288737373063,-0.174946489808922,0.3013745602323828,2.5974544418434338,0.8113589567569786,1.1726596350338454,0.356288737373063,0.8113589567569786,1.6186732764752...
3,643
Rho gtpase effectors
55
128
2.216299
0.026671
Q96F07,Q9HD26,O43684,Q13257,P07737,P68371,Q13526,O60879,P35579,P27361,Q96BT3,P63000,Q15334,P21333,Q2NKX8,P61586,Q8WUW1,Q96EE3,Q9P258,Q9H0B6,P46940,Q7Z460,Q96EA4,Q12834,Q7L576,Q9Y2A7,Q13885,O43683,O75122,P43034,Q9NQS7,Q14204,P63167,Q14738,Q8NFH3,P61160,Q9BVA1,P28482,Q99661,Q99570,Q13576,P30154,O14980,P35580,O75116,P5335...
Processes and pathways
Reactome Pathways
msigdb_reactome
547,669,249,651,746,1093,140,20,384,993,1229,763,924,989,391,645,1134,860,330,325,525,851,1139,180,599,1166,597,296,420,909,1158,308,437,310,1030,432,1149,688,1145,1144,701,1078,811,827,87,588,775,835,226,468,479,354,1109,134,546
1170,2535,811,2391,2462,226,2002,2463,296,249,1732,2257,468,20,87,420,1549,2831,1637,746,3467,1640,3362,989,1367,2413,993,688,2188,1078,2189,1369,1371,1747,2839,3018,2341,384,827,3542,909,1565,525,1758,1462,2846,588,835,2911,2198,479,1658,1846,432,645,2031,2350,1847,1848,1768,763,1380,437,1093,2913,2106,2038,2853,180,1...
0.356288737373063,-0.4759679989713774,0.5802262548677871,-0.37700443540698164,-0.426654247568139,1.3603994825359238,-0.12354184408581988,-0.426654247568139,1.1726596350338454,1.2972687676797499,0.032894232644399175,-0.27667722707748915,0.9297779869287993,3.2878627229397095,2.0239015433854965,0.9897296751660267,0.139093...
3,643
Runx1 regulates transcription of genes involved in differentiation of hscs
22
43
2.212614
0.026924
Q96J02,Q15008,P25789,P60900,P25788,O43242,P51948,P28066,P49720,P62333,O00487,P20618,P61289,P25786,P25787,Q92530,P55036,Q14997,O75832,P51665,Q13200,Q99436
Processes and pathways
Reactome Pathways
msigdb_reactome
146,537,755,644,639,510,274,640,527,529,884,299,433,428,685,495,589,238,340,833,352,939
1263,1913,1914,884,1347,510,340,1074,299,428,685,639,755,640,2620,1076,1184,1561,2190,2628,527,1193,833,274,589,644,433,914,1659,529,1848,2104,1941,352,1101,238,537,495,146,939,1326,1625,1724
0.3013745602323828,-0.07177053677304059,-0.07177053677304059,0.5235857910422159,0.2468749208094238,0.8703239336226946,1.1111613487779155,0.41162409949645146,1.1726596350338454,0.9897296751660267,0.6948631006681812,0.7528747198305642,0.637316184085691,0.7528747198305642,-0.5249504103946776,0.41162409949645146,0.35628873...
3,643
Glioblastoma signaling pathways
6
26
2.21145
0.027005
P06400,P52701,P41743,P11802,O14733,P49815
Processes and pathways
WikiPathways
msigdb_wp
5,163,162,194,53,117
1265,53,2470,3309,1637,5,1450,194,3467,3362,824,1365,2412,518,993,688,2092,906,162,1081,117,163,1768,252,1386,2249
0.3013745602323828,2.377931653766487,-0.426654247568139,-1.1783350652217268,0.08579910129584352,4.54402937594712,0.19278333017529875,1.4883650140779006,-1.4844458628685837,-1.2671010666360616,0.5802262548677871,0.2468749208094238,-0.37700443540698164,0.8703239336226946,0.4673874574355663,0.6948631006681812,-0.174946489...
3,643
Base excision repair
11
18
2.208662
0.027198
P09874,Q9NR33,P18858,P09429,Q9UGN5,P28340,P39748,P29372,P49916,P27695,Q07864
Processes and pathways
KEGG Pathways
msigdb_kegg
298,1044,100,471,620,687,345,231,831,76,768
471,298,1362,1831,100,1641,76,687,231,345,1650,831,1004,768,1044,2880,620,3205
0.9297779869287993,1.1726596350338454,0.2468749208094238,-0.019627057122083305,1.954875734282166,0.08579910129584352,2.093521364597626,0.6948631006681812,1.3603994825359238,1.1111613487779155,0.08579910129584352,0.5802262548677871,0.4673874574355663,0.637316184085691,0.4673874574355663,-0.6699553268222116,0.81135895675...
3,643
Aplasia hypoplasia of fingers
37
111
2.203547
0.027556
P46777,P06400,Q13485,Q5H8A4,Q14999,P42766,O75369,P08708,P62847,P63000,P61313,P60866,Q07020,P62899,P42345,Q9ULP9,Q9UET6,P62854,O94761,Q9Y4P8,Q08J23,P61254,P62244,P62857,P62081,P28482,Q8IWS0,Q6KC79,Q9NVI1,Q93008,Q13363,Q92889,O60885,P61353,P18077,P27635,Q04721
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
125,5,254,777,18,15,632,747,25,763,31,643,531,47,524,50,460,64,297,625,307,80,435,436,434,688,361,490,219,496,700,95,567,592,341,343,351
1913,1265,2001,1435,3305,3278,1732,2256,2897,567,632,2825,3571,297,2900,1741,3282,3307,2007,3333,5,747,3284,2835,341,2769,2411,989,343,688,995,906,2708,3020,1752,1189,524,15,2627,125,2477,2023,1464,3061,832,2774,3317,643,80,31,592,434,435,25,64,436,2099,47,1091,763,2104,3257,351,2426,531,3155,307,1770,700,254,3539,1485...
-0.07177053677304059,0.3013745602323828,-0.12354184408581988,0.19278333017529875,-1.1783350652217268,-1.1335470777869139,0.032894232644399175,-0.27667722707748915,-0.717657624490921,0.8113589567569786,0.7528747198305642,-0.6699553268222116,-2.0610678175841555,1.1726596350338454,-0.717657624490921,0.032894232644399175,-...
3,643
Regulation of protein modification by small protein conjugation or removal
30
95
2.200437
0.027776
P46777,O95999,O43684,P19474,Q13257,Q96J02,Q13526,P31689,P62841,Q9Y263,Q04206,P15880,P60866,Q96JB5,Q8TDB6,Q7Z6Z7,Q12834,P61927,O95071,Q8TAF3,P62081,Q9UHD1,Q9NVI1,Q9UBT2,P53350,Q8N2W9,O75832,P49840,P50750,Q96GX5
Processes and pathways
GO Biological process
msigdb_gobp
125,4,249,11,651,146,140,383,24,157,648,269,643,720,40,315,180,178,424,203,434,621,219,247,588,107,340,584,585,399
1999,1057,249,1732,2257,890,817,3448,1350,340,3516,1175,2690,424,2079,4,1180,896,1925,269,11,1366,2772,3451,383,1282,3018,906,125,1649,2630,3491,584,585,588,1764,643,2200,178,434,1090,24,1091,2777,1938,1385,1094,917,648,2105,1200,180,1946,651,839,1204,1772,140,1485,1577,1209,1493,3582,2434,1406,315,107,203,40,1033,2051...
-0.12354184408581988,0.41162409949645146,1.2972687676797499,0.032894232644399175,-0.27667722707748915,0.5235857910422159,0.5802262548677871,-1.4414863917249552,0.2468749208094238,1.1111613487779155,-1.6955736238491228,0.356288737373063,-0.5736061024396271,0.9897296751660267,-0.174946489808922,4.54402937594712,0.3562887...
3,643
Cross presentation of soluble exogenous antigens endosomes
20
38
2.196219
0.028076
Q15008,P25789,P60900,P25788,O43242,P28066,P49720,P62333,O00487,P20618,P61289,P25786,P25787,Q92530,P55036,Q14997,O75832,P51665,Q13200,Q99436
Processes and pathways
Reactome Pathways
msigdb_reactome
537,755,644,639,510,640,527,529,884,299,433,428,685,495,589,238,340,833,352,939
1263,1913,1914,884,1347,510,340,1074,299,428,685,639,755,640,2620,1076,1184,1561,2190,2628,527,1193,833,589,644,433,914,1659,529,1941,352,238,537,495,939,1326,1625,1724
0.3013745602323828,-0.07177053677304059,-0.07177053677304059,0.5235857910422159,0.2468749208094238,0.8703239336226946,1.1111613487779155,0.41162409949645146,1.1726596350338454,0.9897296751660267,0.6948631006681812,0.7528747198305642,0.637316184085691,0.7528747198305642,-0.5249504103946776,0.41162409949645146,0.35628873...
3,643
Degradation of axin
20
38
2.196219
0.028076
Q15008,P25789,P60900,P25788,O43242,P28066,P49720,P62333,O00487,P20618,P61289,P25786,P25787,Q92530,P55036,Q14997,O75832,P51665,Q13200,Q99436
Processes and pathways
Reactome Pathways
msigdb_reactome
537,755,644,639,510,640,527,529,884,299,433,428,685,495,589,238,340,833,352,939
1263,1913,1914,884,1347,510,340,1074,299,428,685,639,755,640,2620,1076,1184,1561,2190,2628,527,1193,833,589,644,433,914,1659,529,1941,352,238,537,495,939,1326,1625,1724
0.3013745602323828,-0.07177053677304059,-0.07177053677304059,0.5235857910422159,0.2468749208094238,0.8703239336226946,1.1111613487779155,0.41162409949645146,1.1726596350338454,0.9897296751660267,0.6948631006681812,0.7528747198305642,0.637316184085691,0.7528747198305642,-0.5249504103946776,0.41162409949645146,0.35628873...
3,643
Mrna 5 utr binding
10
21
2.196136
0.028082
P46777,P34896,P61254,P62081,Q06787,Q6PKG0,P61247,Q9H2U1,P62263,P62277
Functions
GO Molecular function
msigdb_gomf
125,475,80,434,530,779,480,726,348,387
2166,1999,2325,2171,3216,475,2552,827,125,1192,480,80,434,348,387,530,779,2135,726,1894,2679
-0.2259898614760554,-0.12354184408581988,-0.3270137385950589,-0.2259898614760554,-1.0431437506361978,0.9297779869287993,-0.4759679989713774,0.5802262548677871,1.8186080128566493,0.356288737373063,0.9297779869287993,2.093521364597626,0.9897296751660267,1.1111613487779155,1.050187786825878,0.8703239336226946,0.6373161840...
3,643
E2f mediated regulation of dna replication
10
14
2.195992
0.028092
P06400,P14635,Q14181,P49643,P49642,Q9Y619,Q9UBD5,P09884,P30154,O43913
Processes and pathways
Reactome Pathways
msigdb_reactome
5,124,182,830,829,807,459,982,1078,511
511,1731,5,1069,982,124,2188,1078,829,830,3119,182,459,807
0.8703239336226946,0.032894232644399175,4.54402937594712,0.41162409949645146,0.4673874574355663,1.8186080128566493,-0.2259898614760554,0.41162409949645146,0.5802262548677871,0.5802262548677871,-0.9054161621172195,1.553221452559307,0.9897296751660267,0.637316184085691
3,643
Negative regulation of nuclear division
10
24
2.194655
0.028188
Q5JVF3,P14635,O43684,Q969U7,O14757,P53350,Q13257,O43670,P33981,O43683
Processes and pathways
GO Biological process
msigdb_gobp
487,124,249,244,337,588,651,379,520,296
337,2002,2003,379,296,249,3278,2257,637,124,520,1462,588,3289,651,1398,487,2436,244,1880,1139,2935,1811,1431
1.1111613487779155,-0.12354184408581988,-0.12354184408581988,1.050187786825878,1.1726596350338454,1.2972687676797499,-1.1335470777869139,-0.27667722707748915,0.7528747198305642,1.8186080128566493,0.8703239336226946,0.19278333017529875,0.8113589567569786,-1.1335470777869139,0.7528747198305642,0.2468749208094238,0.929777...
3,643
Initiation factor
20
39
2.188593
0.028626
Q9BY44,O43432,O75821,P41214,O15371,Q9ULC4,Q7Z478,Q14232,Q13144,O60841,Q9UBQ5,Q04637,P41567,P55884,Q13347,P20042,P49770,Q9UI10,Q14152,O43583
Functions
Protein Atlas Molecular function
protein_atlas_molecular_function
288,739,894,161,886,190,314,919,440,173,619,595,90,836,840,342,234,804,130,972
1264,886,970,739,972,1826,173,894,2006,1550,1358,342,1644,1188,161,90,1932,234,1086,836,2633,1196,1766,1661,595,440,840,130,919,2972,2724,1784,314,288,1249,619,804,190,1818
0.3013745602323828,0.5235857910422159,0.4673874574355663,0.637316184085691,0.4673874574355663,-0.019627057122083305,1.553221452559307,0.5235857910422159,-0.12354184408581988,0.13909345271370782,0.2468749208094238,1.1111613487779155,0.08579910129584352,0.356288737373063,1.6186732764752128,2.0239015433854965,-0.071770536...
3,643
Regulation of microtubule depolymerization
6
10
2.183769
0.028979
Q66K74,P29372,P78559,Q7Z460,O15344,O75122
Processes and pathways
GO Biological process
msigdb_gobp
443,231,280,851,294,420
294,420,231,910,280,443,851,1596,1695,2159
1.1726596350338454,0.9897296751660267,1.3603994825359238,0.5235857910422159,1.234692175919743,0.9897296751660267,0.5802262548677871,0.13909345271370782,0.08579910129584352,-0.174946489808922
3,643
Neoplasm of the large intestine
18
49
2.18156
0.029142
P46777,Q13485,O43684,P52701,P61254,P63167,P62081,P62244,P18077,P62899,Q8NFG4,P42766,P20585,P54277,P62847,P62854,P61313,O43683
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
125,254,249,163,80,437,434,435,341,47,82,15,381,347,25,64,31,296
810,296,249,2257,2470,3309,747,1926,3467,341,381,3313,687,2550,3018,906,1752,15,997,125,2477,163,2420,347,643,80,31,592,434,435,25,64,436,47,1091,437,531,768,2353,254,3318,2359,1398,1019,1681,82,2050,1900,962
0.5802262548677871,1.1726596350338454,1.2972687676797499,-0.27667722707748915,-0.426654247568139,-1.1783350652217268,0.637316184085691,-0.07177053677304059,-1.4844458628685837,1.1111613487779155,1.050187786825878,-1.1783350652217268,0.6948631006681812,-0.4759679989713774,-0.8121388295267228,0.5235857910422159,0.0328942...
3,643
Scf skp2 mediated degradation of p27 p21
23
42
2.179864
0.029268
Q15008,P25789,P60900,P25788,O43242,P28066,P24941,P49720,P62333,O00487,Q13616,P20618,P61289,P25786,P25787,P11802,Q92530,P55036,Q13309,O75832,P51665,Q13200,Q99436
Processes and pathways
Reactome Pathways
msigdb_reactome
537,755,644,639,510,640,518,527,529,884,533,299,433,428,685,194,495,589,839,340,833,352,939
1263,1913,1914,884,1347,510,340,194,1074,299,518,428,685,639,755,640,2620,1076,1184,1561,2190,2628,527,1193,833,589,644,433,914,1659,529,2777,1941,352,839,533,537,495,939,1326,1625,1724
0.3013745602323828,-0.07177053677304059,-0.07177053677304059,0.5235857910422159,0.2468749208094238,0.8703239336226946,1.1111613487779155,1.4883650140779006,0.41162409949645146,1.1726596350338454,0.8703239336226946,0.9897296751660267,0.6948631006681812,0.7528747198305642,0.637316184085691,0.7528747198305642,-0.524950410...
3,643
Condensation of prometaphase chromosomes
9
10
2.178452
0.029372
P06493,P14635,O95067,Q9BPX3,P19784,Q9NTJ3,Q15021,O95347,Q15003
Processes and pathways
Reactome Pathways
msigdb_reactome
1069,124,6,862,987,290,654,569,922
6,569,1069,124,987,1092,922,654,862,290
4.3689581005135825,0.8113589567569786,0.41162409949645146,1.8186080128566493,0.4673874574355663,0.41162409949645146,0.5235857910422159,0.7528747198305642,0.5802262548677871,1.234692175919743
3,643
Acute leukemia
20
47
2.172875
0.02979
P46777,O43684,P42766,Q9Y3A5,P62847,P61313,Q07020,P62899,P62854,O43683,Q08J23,P61254,P62081,P62857,P62244,Q5F1R6,P61353,P18077,P11766,P62263
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
125,249,15,562,25,31,531,47,64,296,307,80,434,436,435,93,592,341,473,348
296,249,2257,2259,2397,976,3309,1924,747,473,341,3285,1749,1752,15,997,3518,125,2477,2420,643,913,80,31,592,434,435,348,25,64,436,2562,47,1091,531,307,3432,2214,1101,1778,1398,93,1862,2873,2304,1047,562
1.1726596350338454,1.2972687676797499,-0.27667722707748915,-0.27667722707748915,-0.37700443540698164,0.4673874574355663,-1.1783350652217268,-0.07177053677304059,0.637316184085691,0.9297779869287993,1.1111613487779155,-1.1335470777869139,0.032894232644399175,0.032894232644399175,3.528575244639867,0.4673874574355663,-1.6...
3,643
Translation factor activity rna binding
34
57
2.172796
0.029796
O15372,Q9Y450,P55010,Q9BY44,O43432,P13639,Q8NE71,O75821,P41214,Q92905,O15371,Q9ULC4,Q92616,Q7Z478,Q9NR50,Q14232,Q13144,O60841,P41091,P26641,P15170,Q9UBQ5,Q04637,P62495,Q05639,P41567,P55884,Q13347,P20042,P49770,P63241,Q9UI10,Q14152,O43583
Functions
GO Molecular function
msigdb_gomf
970,959,1086,288,739,897,447,894,161,717,886,190,187,314,1249,919,440,173,1188,1183,1182,619,595,594,698,90,836,840,342,234,482,804,130,972
1997,1264,886,970,739,972,1826,173,894,2006,1550,1358,897,1182,342,1644,2013,1183,1558,1188,161,90,2343,1932,2345,234,1086,836,2633,1196,1766,594,482,1661,595,698,440,840,130,1774,919,2972,2724,1784,1862,314,447,187,717,1701,288,1249,619,804,190,1818,959
-0.12354184408581988,0.3013745602323828,0.5235857910422159,0.4673874574355663,0.637316184085691,0.4673874574355663,-0.019627057122083305,1.553221452559307,0.5235857910422159,-0.12354184408581988,0.13909345271370782,0.2468749208094238,0.5235857910422159,0.356288737373063,1.1111613487779155,0.08579910129584352,-0.1235418...
3,643
Rna cap binding
6
12
2.172373
0.029828
Q8TEQ6,Q6PKG0,O43432,Q96C86,Q96F07,Q7L576
Functions
GO Molecular function
msigdb_gomf
789,779,739,189,547,599
886,739,1826,1358,1766,1572,2212,779,599,789,189,547
0.5235857910422159,0.637316184085691,-0.019627057122083305,0.2468749208094238,0.032894232644399175,0.13909345271370782,-0.2259898614760554,0.637316184085691,0.8113589567569786,0.637316184085691,1.553221452559307,0.8703239336226946
3,643
Base excision repair
13
30
2.171336
0.029906
P09874,Q9NR33,Q9UGN5,P18858,P28340,P39748,P35251,P15927,P27695,P49916,P29372,P35244,Q07864
Processes and pathways
Reactome Pathways
msigdb_reactome
298,1044,620,100,687,345,101,823,76,831,231,54,768
298,1362,1831,823,100,1641,1745,76,687,231,54,1930,2475,101,345,2094,1286,1650,831,1004,1848,768,1867,1975,1044,2880,1335,2064,620,3205
1.1726596350338454,0.2468749208094238,-0.019627057122083305,0.5802262548677871,1.954875734282166,0.08579910129584352,0.032894232644399175,2.093521364597626,0.6948631006681812,1.3603994825359238,2.377931653766487,-0.07177053677304059,-0.426654247568139,1.954875734282166,1.1111613487779155,-0.174946489808922,0.3013745602...
3,643
Proteasome
25
36
2.166412
0.03028
Q99460,Q15008,P25789,P60900,P25788,O43242,P28066,P49720,P62333,O00487,P62191,P20618,P28074,P61289,P25786,P25787,Q92530,P28072,P17980,P49721,P55036,Q14997,P51665,Q13200,Q99436
Processes and pathways
KEGG Pathways
msigdb_kegg
1326,537,755,644,639,510,640,527,529,884,914,299,1184,433,428,685,495,1076,1074,1193,589,238,833,352,939
1263,1913,884,1347,510,1074,299,428,685,639,755,640,2620,1076,1184,1561,2190,2628,527,1193,833,589,644,433,914,1659,529,1941,352,238,537,495,939,1326,1625,1724
0.3013745602323828,-0.07177053677304059,0.5235857910422159,0.2468749208094238,0.8703239336226946,0.41162409949645146,1.1726596350338454,0.9897296751660267,0.6948631006681812,0.7528747198305642,0.637316184085691,0.7528747198305642,-0.5249504103946776,0.41162409949645146,0.356288737373063,0.13909345271370782,-0.225989861...
3,643
DNA replication
28
62
2.165062
0.030383
Q9BTE3,Q9Y3Z3,Q9NZJ0,Q7LG56,Q8WVB6,Q07864,O43913,P25205,P33991,Q96S55,Q14181,Q9UBD5,Q7L590,P35244,P28340,P15927,Q9Y5B9,Q96RR1,Q08945,P33992,P18858,P51530,P49736,P39748,P35251,P49642,P49643,P49916
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
403,413,291,141,153,768,511,271,521,861,182,459,184,54,687,823,223,366,212,577,100,104,583,345,101,829,830,831
511,1731,2396,2688,2403,982,1362,823,100,991,271,1745,687,1185,521,577,1079,54,1930,2475,101,345,2094,1286,1650,1934,829,830,583,831,104,2420,1004,2851,768,2636,212,2209,1771,2487,3119,182,1776,2114,1498,184,141,2045,153,366,861,941,1235,1238,2131,403,291,459,2066,2603,413,223
0.8703239336226946,0.032894232644399175,-0.37700443540698164,-0.5736061024396271,-0.37700443540698164,0.4673874574355663,0.2468749208094238,0.5802262548677871,1.954875734282166,0.4673874574355663,1.234692175919743,0.032894232644399175,0.6948631006681812,0.356288737373063,0.8703239336226946,0.8113589567569786,0.41162409...
3,643
Proximal muscle weakness in lower limbs
7
22
2.164502
0.030426
Q8WZ42,Q14204,Q7LG56,P50570,Q00796,Q96RR1,Q8NCE2
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
169,308,141,478,21,366,543
2827,3333,2698,1448,1927,2093,2193,478,1764,21,534,308,1487,1779,141,543,3161,2868,169,366,3033,1910
-0.6699553268222116,-1.2228519251976793,-0.5736061024396271,0.19278333017529875,-0.07177053677304059,-0.174946489808922,-0.2259898614760554,0.9297779869287993,0.032894232644399175,3.2087982428782533,0.8703239336226946,1.1726596350338454,0.19278333017529875,0.032894232644399175,1.7513670427695411,0.8703239336226946,-0.9...
3,643
Dna replication
17
33
2.161206
0.030679
P33992,P24941,P25205,P33991,Q14181,P28340,P49736,Q9UBD5,P15927,P49642,Q7L590,P35251,P49643,Q9Y619,P35244,Q07864,O43913
Processes and pathways
WikiPathways
msigdb_wp
577,518,271,521,182,687,583,459,823,829,184,101,830,807,54,768,511
511,1731,2688,982,1362,823,518,271,1745,687,521,577,1079,54,1930,2475,101,2094,1286,1650,829,830,583,1004,768,3119,182,1776,184,941,459,3205,807
0.8703239336226946,0.032894232644399175,-0.5736061024396271,0.4673874574355663,0.2468749208094238,0.5802262548677871,0.8703239336226946,1.234692175919743,0.032894232644399175,0.6948631006681812,0.8703239336226946,0.8113589567569786,0.41162409949645146,2.377931653766487,-0.07177053677304059,-0.426654247568139,1.95487573...
3,643
Ribonucleoprotein granule
32
115
2.156625
0.031035
Q92499,P19474,Q9Y520,P25789,A5YKK6,P60900,P67809,Q06787,P46940,Q96F86,Q96C86,Q9HAU5,Q9H2U1,Q9Y333,Q7L8L6,P62753,Q9BYJ9,P54646,P62701,Q08J23,P25787,Q04637,P11940,Q7Z417,Q15365,O75116,Q14671,Q02878,O95793,Q6PKG0,P46779,P50750
Localization
GO Cellular component
msigdb_gocc
544,11,563,755,507,644,32,530,525,608,189,728,726,59,600,63,613,303,305,307,685,595,684,359,705,87,485,237,470,779,232,585
507,1999,1824,1826,87,2822,1271,893,470,1550,2083,1358,1359,2955,2334,684,3014,1074,3216,11,685,755,2014,3254,1561,828,232,525,585,1759,2710,2845,303,1764,644,1658,2561,3255,2635,305,63,763,32,3368,3118,2035,2036,237,595,530,2483,2636,307,2916,1944,1014,1483,1947,1772,2108,1391,1207,2110,485,2357,705,2725,1954,1779,228...
0.8703239336226946,-0.12354184408581988,-0.019627057122083305,-0.019627057122083305,2.0239015433854965,-0.6699553268222116,0.3013745602323828,0.5235857910422159,0.9297779869287993,0.13909345271370782,-0.174946489808922,0.2468749208094238,0.2468749208094238,-0.7650507386283446,-0.3270137385950589,0.6948631006681812,-0.8...
3,643
Nucleotide excision repair
14
25
2.155897
0.031092
P51948,P19447,P54725,P28340,O60921,Q16658,Q96T76,P41208,P15927,Q96EB6,P35244,Q92889,Q07864,P18074
Processes and pathways
GO Biological process
msigdb_gobp
274,427,528,687,892,1019,722,523,823,937,54,95,768,270
892,2403,3309,982,823,270,427,1745,687,2838,54,523,274,528,2964,768,1491,1019,95,1696,937,1975,722,1804,2145
0.5235857910422159,-0.37700443540698164,-1.1783350652217268,0.4673874574355663,0.5802262548677871,1.234692175919743,0.9897296751660267,0.032894232644399175,0.6948631006681812,-0.6699553268222116,2.377931653766487,0.8703239336226946,1.234692175919743,0.8703239336226946,-0.7650507386283446,0.637316184085691,0.19278333017...
3,643
Intrinsic component of organelle membrane
81
149
6.368595
0
O60830,Q99595,Q9H4I9,Q9Y2R0,P27824,O76024,Q13505,P10321,Q86YN1,Q9BUN8,Q9Y282,Q9NWR8,Q15629,P42892,Q15070,Q99442,Q8N4V1,Q8N8Q8,Q9NQC3,P57105,Q9BTV4,P30511,Q5BJH7,O95070,O60499,P0DJ07,Q8N2H4,Q9GZY8,Q86XL3,Q5XKP0,Q8TB61,O75844,Q53H12,O95470,Q9H3K2,Q12981,O75298,O14925,Q9BUR5,O43292,Q5T9L3,Q9BWH2,L0R6Q1,Q96A33,Q9UG56,Q6Y1H...
Localization
GO Cellular component
msigdb_gocc
0,5,10,17,531,529,32,540,43,48,60,581,62,576,67,589,77,84,86,90,93,97,99,102,114,116,121,123,125,141,150,159,165,181,183,203,204,216,241,243,253,255,266,269,281,292,299,300,302,313,316,321,322,320,350,354,368,382,386,392,390,393,398,414,416,424,426,425,447,455,467,463,477,485,486,490,500,499,492,504,508
1170,266,651,216,858,447,504,243,2283,623,720,393,300,114,0,204,492,159,368,529,1869,1901,1823,102,1024,181,908,485,2494,1026,116,540,508,750,831,2201,3221,531,2604,97,2800,576,1276,463,1640,486,382,90,862,2372,846,2110,848,2378,203,32,2506,320,1070,321,67,1126,490,62,2009,1883,416,165,99,313,1129,398,253,141,752,477,4...
0.2129676082349203,1.5251418478775813,0.684682551459923,1.7075469085996575,0.44095258539286264,1.0519791774245264,0.9411256311783628,1.6119122366380962,-0.3611270737979477,0.7371343864831222,0.591424850029758,1.1720512731971409,1.4254643571680072,2.3153456822870413,3.8634295457323278,1.759799474752132,0.953577092212266...
3,643
Ion transmembrane transporter activity
70
124
5.141346
0
Q96ES6,P00403,P21796,O75964,O43772,P00846,Q93050,Q9Y619,O43808,P45880,Q9BQT8,P13073,P06576,Q8TB61,O95202,Q7KZN9,Q96S66,Q9UDW1,Q9BVC6,P08195,P30825,P20674,Q01650,P21281,Q9Y5K8,P53985,Q6P4Q7,Q9H2D1,Q9Y277,Q6NUK1,O15439,P41440,Q9UBX3,P00395,Q9NWR8,Q9HC21,P16615,O14548,Q9UJS0,Q9H9B4,P20020,P08574,P05023,Q8N1S5,Q8N4V1,P9819...
Functions
GO Molecular function
msigdb_gomf
130,133,9,12,270,15,143,273,393,19,279,149,530,150,152,153,668,27,407,161,672,541,37,294,697,172,691,178,179,436,817,821,58,819,581,322,317,451,718,717,831,830,829,76,77,846,462,844,342,88,842,92,94,477,224,475,861,613,491,748,500,371,249,372,768,244,122,508,509,127
3057,372,451,2239,817,491,270,393,1928,1079,12,152,908,819,133,15,944,829,1100,842,530,2405,1493,3171,161,830,748,977,844,508,462,149,317,2071,831,541,294,3632,9,1174,475,1232,672,1080,1874,613,873,1703,821,19,1045,3199,1148,860,509,948,172,1357,861,244,1217,2372,846,2110,3597,37,1047,1152,1069,1002,1049,1182,342,3612,...
-0.7925324929496625,1.21920071301935,1.0397949556104586,-0.34465654335830465,0.48247922194350323,0.9535770922122667,1.514175794039268,1.1720512731971409,-0.1989415716579973,0.27102098199975727,3.635267768351748,2.041502140292411,0.39904986077081717,0.48247922194350323,2.175850808055284,3.567693886328488,0.3709026494296...
3,643
Mitochondrion organization
87
224
5.004012
0.000001
O60830,Q99595,Q9NS69,Q8N4H5,P14406,P21796,O43676,Q9Y2R0,P45880,Q9H061,Q8N2A8,Q13505,Q96A26,Q86Y39,P30536,Q69YU5,Q9NUQ9,P27544,Q96CU9,Q15070,P03886,Q9UDX5,Q9Y6C9,Q8N8Q8,Q9Y241,Q9Y584,P0DJ07,Q9GZY8,Q5XKP0,O95202,O75438,O75153,Q53H12,O95167,Q6DKK2,Q9H3K2,Q9BSK2,Q9Y6M9,O14925,Q9NVI7,Q99797,Q99623,O95139,Q9BUR5,Q9H4A6,Q96I3...
Processes and pathways
GO Biological process
msigdb_gobp
0,5,7,3,2,9,13,17,19,20,25,32,39,44,47,52,55,59,66,67,72,81,83,84,104,111,116,123,141,152,158,157,165,171,173,183,214,215,216,234,235,238,240,241,242,247,255,265,274,281,277,283,284,289,300,302,304,306,338,345,355,368,381,388,392,390,416,418,426,425,420,432,444,451,457,467,464,461,485,486,490,502,493,492,505,503,507
1268,306,784,2882,857,1551,451,503,216,2631,2194,611,284,13,2327,300,345,0,1753,157,3374,1023,785,1214,492,158,1660,1121,2065,368,1901,240,1024,171,420,616,152,1594,2938,2668,1553,3537,355,338,485,688,2600,72,1297,461,2796,507,842,1663,2633,3033,116,795,3153,2246,1906,508,2,2737,9,59,3220,3014,758,2435,2829,47,1044,170...
0.13936941440617376,1.4030088099179048,0.5236359569657166,-0.6677690785969682,0.44095258539286264,-0.011395355835454363,1.0397949556104586,0.9411256311783628,1.7075469085996575,-0.5290467050709876,-0.32824295987150115,0.7631368818205105,1.4700401884505825,3.6218409135416008,-0.3776549171329734,1.4254643571680072,1.2890...
3,643
Organelle inner membrane
123
287
4.948987
0.000001
O60830,Q99595,Q9Y6N5,P14406,Q9H2V7,Q9H4I9,O75964,O43676,P82933,Q7Z7H8,Q9Y2R0,P00846,Q9H061,O14949,P06576,Q9UDW1,Q9BRJ2,Q13505,P20674,P36551,Q86Y39,Q99720,Q8WUK0,Q69YU5,P09669,Q9UBX3,Q9NWR8,Q9BYD1,Q96CU9,Q15070,P03886,Q9UDX5,Q9Y6C9,Q8N8Q8,O75027,Q70HW3,Q9BTV4,O43615,P36542,Q9Y241,O95169,P23786,Q9Y584,P0DJ07,Q9BRT2,Q8IXM...
Localization
GO Cellular component
msigdb_gocc
0,5,520,2,526,10,12,13,522,16,17,15,20,21,530,27,546,32,541,551,44,50,561,52,568,58,581,579,66,67,72,81,83,84,597,88,93,611,613,104,616,107,111,116,644,126,127,635,133,648,649,141,658,145,149,152,153,159,158,165,166,167,171,173,178,183,214,215,216,226,234,238,240,241,244,265,270,273,279,281,277,283,284,289,300,303,314,...
857,1346,451,216,21,611,284,13,2327,270,300,345,0,597,1023,785,635,492,158,1660,1121,1661,1954,1928,159,368,1079,12,2599,1869,1823,240,171,420,616,1459,152,1594,908,687,355,338,485,819,133,15,72,1297,1635,842,530,1992,830,3080,2633,568,116,977,3153,2246,508,462,1871,149,2,756,1103,1196,1636,2071,3035,541,909,431,2917,1...
0.44095258539286264,0.09464742558718883,1.0397949556104586,1.7075469085996575,3.422104212978296,0.7631368818205105,1.4700401884505825,3.6218409135416008,-0.3776549171329734,1.514175794039268,1.4254643571680072,1.2890126041449141,3.8634295457323278,0.7889925013317961,0.3140906358105457,0.5236359569657166,0.7109834670817...
3,643
Transporter activity
127
217
4.92213
0.000001
O60830,Q99595,Q9NS69,Q9H2V7,P21796,O75964,O43676,P00846,P45880,P06576,Q96AA3,Q9UDW1,P20674,Q01650,P30536,Q9UBX3,Q9NWR8,Q9Y3B1,P03886,Q8N1S5,Q8N4V1,O15173,Q7L0J3,O75027,Q70HW3,Q8NEW0,Q9HD20,P36542,Q8NE01,O95169,Q9Y584,P08183,Q8IUH4,Q86VD7,Q96ES6,O75380,P00403,Q93050,P56556,P13073,Q8TB61,O95202,Q7KZN9,Q96S66,Q96H78,P0819...
Functions
GO Molecular function
msigdb_gomf
0,5,7,526,9,12,13,15,19,530,534,27,541,37,47,58,581,74,72,76,77,78,594,597,88,92,94,613,614,616,111,625,122,127,130,635,133,143,654,149,150,152,153,668,156,161,672,158,171,697,172,691,178,179,718,717,198,201,214,215,216,224,736,235,748,240,249,245,244,768,251,259,265,266,270,273,279,785,284,289,294,815,825,817,821,819,...
266,201,857,3057,372,1346,2026,451,736,2239,216,858,78,817,504,284,13,2327,491,270,393,0,597,1023,785,635,158,1121,1928,1079,12,1901,240,171,420,616,1459,152,1594,908,338,485,819,133,15,72,1297,461,944,829,1100,842,530,2405,1493,3171,625,161,830,748,977,844,508,462,149,317,3282,2071,3035,831,541,294,3632,9,2202,1174,47...
1.5251418478775813,1.7805289975127767,0.44095258539286264,-0.7925324929496625,1.21920071301935,0.09464742558718883,-0.24701667429505778,1.0397949556104586,0.5779466188099379,-0.34465654335830465,1.7075469085996575,0.44095258539286264,2.5556521085871906,0.48247922194350323,0.9411256311783628,1.4700401884505825,3.6218409...
3,643
Protein targeting
45
132
4.727709
0.000002
O60830,Q99595,Q9NS69,Q9Y5J7,P46379,Q8N4H5,Q9Y3D6,Q9Y5J9,Q5JRX3,Q9H300,Q9P0J0,Q9Y5M8,P43307,Q53H12,Q9Y512,P30536,O00165,Q15005,Q15041,Q15629,Q7L5D6,P31751,Q9UNL2,O00189,Q9Y5J6,P55786,O14925,P57105,Q86WA8,Q5BJH7,O95831,O96008,P51572,Q14108,O60725,Q99797,Q15388,O43681,Q9Y371,Q9Y584,P40855,Q10713,Q96RL7,Q9Y5L4,Q9GZY8
Processes and pathways
GO Biological process
msigdb_gobp
0,5,7,388,134,3,392,265,274,283,289,163,36,165,426,47,306,312,321,62,450,325,328,201,457,464,216,90,353,99,355,485,486,232,106,235,490,491,502,111,377,493,505,381,123
3102,306,784,201,2882,2793,3574,503,1490,216,1491,611,491,1695,106,0,573,1660,2823,1901,1024,2668,1553,3537,355,485,1663,2939,3127,3153,2246,1122,750,2737,1554,1104,2203,3220,47,1908,325,1250,1385,3284,2576,377,36,134,789,1106,1602,911,1640,486,464,90,1216,2608,2139,1966,2372,1605,776,1738,1560,1838,3597,493,3041,630,2...
-0.8287815921428723,1.4030088099179048,0.5236359569657166,1.7805289975127767,-0.6677690785969682,-0.6152759646849048,-1.595762963282852,0.9411256311783628,0.019148074018054462,1.7075469085996575,0.019148074018054462,0.7631368818205105,0.9535770922122667,-0.08863405544569052,2.3518001240062403,3.8634295457323278,0.82750...
3,643
Nuclear outer membrane endoplasmic reticulum membrane network
168
365
4.418371
0.00001
Q96RQ1,Q15382,Q86YB8,Q9Y3B3,Q96AA3,P37268,Q9BRR6,P27824,O76024,Q9UBV2,P67812,Q99735,O95197,P10321,Q8N511,P43307,P04035,Q9BQE5,Q96AG4,Q86YN1,P30519,Q9BUN8,Q99720,P09601,Q8N5M9,Q96G23,P27544,Q9Y282,Q6IAN0,Q15629,Q8TD16,O15269,P24390,Q969V3,Q8N4V1,Q99442,P51648,O15027,Q9NQC3,Q9BV10,Q4ZIN3,Q6NUK4,Q8WVQ1,Q9HD20,Q9BVK6,O1498...
Localization
GO Cellular component
msigdb_gocc
4,514,523,539,534,24,26,531,529,548,31,545,33,540,35,36,549,40,555,43,46,48,50,51,53,56,59,60,572,62,578,582,73,588,77,589,79,591,86,600,89,91,607,94,609,603,97,605,99,101,102,106,620,617,624,117,119,120,630,632,633,124,125,634,138,659,146,655,150,151,651,667,668,155,159,163,164,169,174,181,187,195,196,202,203,204,207,...
1170,1213,2490,239,372,1551,3071,2793,651,2026,1457,458,3631,736,634,1690,1630,1899,603,591,230,582,2325,504,2240,3485,243,2283,684,1401,2884,1379,106,1659,101,204,2130,1523,721,943,351,159,439,975,529,1869,1318,1429,3074,1929,102,33,1633,181,2669,3439,2735,687,264,671,3075,1381,2494,549,1026,624,2067,843,3078,138,2939...
0.2129676082349203,0.18366745927428121,-0.4611668784241816,1.6226405617971547,1.21920071301935,-0.011395355835454363,-0.8106229565179895,-0.6152759646849048,0.684682551459923,-0.24701667429505778,0.03434555447499574,1.0275779101847236,-2.929607055975441,0.5779466188099379,0.7109834670817337,-0.08863405544569052,-0.0575...
3,643
Mitochondrial protein containing complex
61
181
4.403523
0.000011
O60830,Q99595,Q9NS69,Q9Y5J7,Q8N4H5,P14406,P00403,P21796,Q9H4I9,Q9Y5J9,O75964,O43676,Q5XKP0,P82933,Q7Z7H8,P00846,P40939,P56378,O14874,O14949,P06576,P13073,Q9UDW1,O43674,Q9BRJ2,Q13505,O75438,Q9P0J0,Q16891,P20674,Q53H12,Q567V2,Q9Y512,O95168,O95167,Q86Y39,Q9NX63,P21912,P09669,Q9NWR8,Q96CU9,O14548,Q9Y5J6,P03886,Q6UXV4,O9600...
Localization
GO Cellular component
msigdb_gocc
0,5,7,388,3,2,133,9,10,265,12,13,141,522,16,15,395,145,148,21,530,149,27,284,546,32,158,289,416,541,165,166,426,420,171,44,390,431,568,581,66,451,457,72,467,338,462,215,216,474,475,485,490,238,111,240,241,492,244,381,508
857,2694,1171,1346,451,148,216,21,1866,284,13,2327,1521,0,1023,785,635,492,158,1121,1079,12,2599,1901,240,171,420,616,1459,1594,338,485,819,133,15,72,1297,842,530,2329,830,3080,663,568,3172,977,806,2163,508,462,149,2,756,1103,2071,3035,541,9,431,1064,475,1232,3014,2435,1828,1080,708,613,2800,395,1045,3199,1601,3391,322...
0.44095258539286264,-0.5633520351399934,0.2129676082349203,0.09464742558718883,1.0397949556104586,2.0609493316626257,1.7075469085996575,3.422104212978296,-0.16716107737328262,1.4700401884505825,3.6218409135416008,-0.3776549171329734,0.0039012029953633324,3.8634295457323278,0.3140906358105457,0.5236359569657166,0.710983...
3,643
Mitochondrial envelope
160
374
4.256642
0.000021
O60830,Q99595,Q9NS69,Q9Y6N5,Q8N4H5,P14406,P21796,Q9H4I9,Q9H2V7,O75964,O43676,P00846,Q7Z7H8,Q9Y2R0,P82933,P45880,Q9H061,O14949,P52888,Q9HCL2,P06576,Q8N2A8,Q9UDW1,O43169,Q9BRJ2,Q13505,P20674,Q96A26,P36551,Q8WY22,Q86Y39,P30536,Q8WUK0,P09601,Q69YU5,P09669,Q9UBX3,Q9NWR8,Q9BYD1,Q96CU9,Q15070,Q9Y3B1,P03886,Q9UDX5,Q9Y6C9,Q8N8Q...
Localization
GO Cellular component
msigdb_gocc
0,5,7,520,3,2,9,10,526,12,13,15,16,17,522,19,20,21,521,23,530,25,27,28,546,32,541,39,551,41,44,47,561,51,52,568,58,581,579,66,67,74,72,81,83,84,597,88,90,98,611,613,104,107,616,618,111,113,116,629,119,631,123,124,644,127,635,133,648,649,141,658,145,149,152,153,154,156,158,165,166,171,173,178,179,183,203,214,215,216,226...
306,857,239,1551,1346,3534,3636,451,3560,216,21,942,1867,28,611,284,13,2327,270,300,345,2884,0,597,1023,785,1214,635,492,158,1660,1121,1661,1954,1928,368,1079,12,2599,1901,240,1024,171,420,616,1459,152,1594,908,2735,687,355,338,485,1381,819,133,15,72,1297,1635,842,530,1992,830,3080,2633,51,568,116,795,977,2069,3153,224...
1.4030088099179048,0.44095258539286264,1.6226405617971547,-0.011395355835454363,0.09464742558718883,-1.4077903980781303,-5.352631459605619,1.0397949556104586,-1.5323051303575352,1.7075469085996575,3.422104212978296,0.37090264942965717,-0.16716107737328262,3.1974548749844005,0.7631368818205105,1.4700401884505825,3.62184...
3,643
Endoplasmic reticulum
86
220
4.025046
0.000057
P37268,P27824,O43169,Q99735,O95197,P43307,P13674,Q96AG4,Q9BUN8,Q96G23,P27544,Q9Y680,P35790,O15269,Q99442,P51648,O15027,Q5HYI8,Q8WUJ1,Q9BV10,Q4ZIN3,Q9NQC3,Q96A57,P04843,Q13438,Q9P2W9,Q9Y6B6,Q86XL3,O14681,O96005,Q15800,O00767,Q96HY6,Q96KC8,Q96S66,P62847,Q9BT22,O95674,O95470,O43852,P84157,Q9BRK0,Q12981,Q96KA5,O60831,Q86UE...
Localization
Protein Atlas Subcellular
protein_atlas_subcellular_location_all
24,531,28,545,33,36,550,555,48,56,59,64,575,582,589,79,591,598,599,600,89,86,110,624,630,120,633,125,634,137,146,651,667,151,668,674,174,687,181,684,189,195,203,210,219,221,230,239,246,243,253,254,258,259,262,269,271,285,286,288,296,298,299,305,310,321,335,343,378,386,402,409,408,414,424,421,428,435,434,439,443,454,470...
239,651,634,1899,591,230,582,1075,28,3485,243,2283,684,285,219,1523,943,439,975,1869,1318,1429,33,1633,181,687,137,1381,624,2067,1788,3519,3077,408,2534,1524,748,2069,3428,2288,550,1757,2289,1931,1636,2290,2495,2032,3621,271,2603,1299,1873,59,1432,3221,531,3498,2604,470,3223,1910,978,575,2606,24,2134,1796,36,996,2607,1...
1.6226405617971547,0.684682551459923,0.7109834670817337,-0.18302459062116297,0.801865710054151,1.6546710303066048,0.8147027698123386,0.27102098199975727,3.1974548749844005,-1.266405537457579,1.6119122366380962,-0.3611270737979477,0.6316243203959113,1.4700401884505825,1.6758970568526532,0.0039012029953633324,0.370902649...
3,643
Transmembrane transport
97
254
3.912057
0.000092
O60830,Q99595,Q9NS69,Q9H2V7,Q9H4I9,P21796,O75964,P00846,P45880,P06576,Q9UDW1,P20674,Q01650,Q9HD26,Q9UBX3,Q9NWR8,Q15629,P22466,O75381,Q8N1S5,Q99442,Q8N4V1,Q7L0J3,O75027,Q70HW3,Q8NEW0,Q9HD20,O43615,P36542,Q8NE01,P23786,Q9Y584,Q8IUH4,Q86VD7,Q96ES6,P00403,P13073,Q8TB61,O95202,Q7KZN9,Q96H78,P08195,O75844,P53985,Q9H2D1,Q9Y27...
Processes and pathways
GO Biological process
msigdb_gobp
0,5,7,526,10,9,12,15,19,530,27,541,37,563,58,581,62,65,573,76,589,77,594,597,88,92,94,611,613,614,107,111,122,127,130,133,149,150,152,153,156,161,159,172,178,179,186,198,201,204,214,216,219,224,235,238,245,244,250,259,266,270,273,279,294,303,304,321,322,319,317,325,342,346,353,355,356,371,372,393,394,407,436,432,451,46...
266,3070,201,3057,372,1346,451,736,2239,216,817,611,828,270,393,1401,3123,0,219,597,3030,1023,204,1214,573,1660,1928,159,975,1079,12,1901,152,908,1870,355,485,819,133,15,1297,461,944,829,1100,394,842,3077,530,2405,1493,3079,3171,625,161,830,748,795,977,3153,844,1350,945,508,462,149,317,3441,2071,2916,831,541,294,3632,3...
1.5251418478775813,-0.8106229565179895,1.7805289975127767,-0.7925324929496625,1.21920071301935,0.09464742558718883,1.0397949556104586,0.5779466188099379,-0.34465654335830465,1.7075469085996575,0.48247922194350323,0.7631368818205105,0.46867841236197944,1.514175794039268,1.1720512731971409,0.06459351975889793,-0.84700887...
3,643
Ion transmembrane transport
86
183
3.854272
0.000116
P21796,Q9H4I9,O75964,P00846,P45880,P06576,Q9UDW1,P20674,Q01650,Q9HD26,Q9UBX3,Q9NWR8,P22466,Q8N1S5,Q8N4V1,O75027,Q70HW3,Q8NEW0,Q9HD20,P36542,P08183,Q8IUH4,Q86VD7,Q96ES6,P00403,P13073,Q8TB61,O95202,Q7KZN9,Q8WWC4,P08195,P30825,O75844,P53985,Q6P4Q7,Q9H2D1,Q9Y277,Q9UHG3,Q9UJS0,Q9H9B4,Q9UMX0,O60831,Q9HC07,Q99623,P0CG08,Q9H0U...
Processes and pathways
GO Biological process
msigdb_gobp
9,10,12,15,19,530,27,541,37,563,58,581,65,76,77,597,88,92,94,613,625,122,127,130,133,149,150,152,153,666,161,672,159,172,691,178,179,186,718,717,734,219,224,238,748,768,244,250,259,776,270,273,279,795,797,294,303,827,817,821,819,321,322,319,317,828,831,830,829,846,342,842,861,371,372,393,394,407,451,462,477,475,483,500...
3057,372,1346,451,2239,817,828,270,393,1401,3123,219,597,3030,1023,1214,1660,1928,159,975,1079,12,152,908,1870,819,133,15,1297,944,829,1100,394,842,3077,530,2405,1493,3079,3171,625,161,830,748,795,977,945,508,462,149,317,3441,2071,2916,831,541,294,3632,3523,9,65,1174,475,1232,1104,3220,2887,2435,2293,672,1080,1874,2918...
-0.7925324929496625,1.21920071301935,0.09464742558718883,1.0397949556104586,-0.34465654335830465,0.48247922194350323,0.46867841236197944,1.514175794039268,1.1720512731971409,0.06459351975889793,-0.8470088757604822,1.6758970568526532,0.7889925013317961,-0.7745097302990005,0.3140906358105457,0.18366745927428121,-0.073084...
3,643
Atp metabolic process
40
122
3.830916
0.000128
O75380,P00403,P14406,Q9Y3D6,O75964,O43676,P00846,P56556,P05067,Q9UKK9,O14949,P06576,P13073,Q7KZN9,Q9BRR6,Q9UDW1,O43674,P09622,O75438,P20674,P21281,O95168,O95167,P30536,Q9NRA0,P52789,Q9H3K2,O14548,P03886,O96000,Q9BSK2,Q9Y6M9,Q6KCM7,P24539,P36542,O95169,O95139,P56385,P04637,Q9BRT2
Processes and pathways
GO Biological process
msigdb_gobp
635,133,2,392,12,13,15,654,394,537,21,530,149,153,26,27,284,663,158,541,294,420,171,47,303,304,183,451,72,338,214,215,342,475,613,616,240,244,507,644
857,1551,1346,451,21,1867,284,13,2327,1023,785,1214,635,158,1121,1928,1079,12,2599,240,171,420,616,1459,1594,338,3061,819,133,3013,2161,15,72,1297,3362,2066,507,1100,394,843,530,3078,2362,2534,830,2363,663,3033,3513,1272,977,1122,149,2,1958,756,1103,3155,1430,2071,2699,3035,541,294,1064,475,1232,1198,3014,2435,47,1828,...
0.44095258539286264,-0.011395355835454363,0.09464742558718883,1.0397949556104586,3.422104212978296,-0.16716107737328262,1.4700401884505825,3.6218409135416008,-0.3776549171329734,0.3140906358105457,0.5236359569657166,0.18366745927428121,0.7109834670817337,2.0023469353928545,0.24208474921036938,-0.1989415716579973,0.2710...
3,643
Cation transmembrane transport
62
141
3.671972
0.000241
Q96ES6,Q96GC9,P00403,P21796,Q9H4I9,O75964,P62258,O43772,P00846,Q9Y619,P05067,P13073,P06576,O95202,Q7KZN9,Q9UDW1,Q8WWC4,P08195,P30825,P0DP25,P20674,Q01650,Q06787,P21281,Q9NRA0,Q6P4Q7,Q9UJZ1,P00395,Q9NWR8,Q9HC21,P62942,P22466,P16615,O14548,O43707,P20020,Q9H9B4,P08574,P05023,Q8N1S5,Q8N4V1,Q9UMX0,P98194,O75027,Q6KCM7,Q70HW...
Processes and pathways
GO Biological process
msigdb_gobp
130,259,133,9,10,12,776,270,15,273,394,149,530,152,153,27,666,161,672,795,541,37,797,294,303,691,827,819,581,322,319,65,317,451,828,831,717,830,829,76,77,734,846,597,342,88,842,92,94,475,224,483,613,250,238,500,371,372,768,244,122,508
372,1346,451,2239,828,270,3123,597,1023,1214,1660,1079,12,152,1870,819,133,15,1297,829,1100,394,842,3077,530,2405,1493,3079,3171,161,830,795,977,945,508,149,317,3441,2071,2916,831,541,294,3632,3523,9,65,1174,475,1232,1104,3220,2887,2435,2293,672,1080,2918,613,873,1703,2742,1045,3199,1253,1148,1735,1388,1357,861,244,121...
1.21920071301935,0.09464742558718883,1.0397949556104586,-0.34465654335830465,0.46867841236197944,1.514175794039268,-0.8470088757604822,0.7889925013317961,0.3140906358105457,0.18366745927428121,-0.07308450629753695,0.27102098199975727,3.635267768351748,2.041502140292411,-0.16716107737328262,0.48247922194350323,2.1758508...
3,643
Organelle subcompartment
204
452
3.593969
0.000326
Q96RQ1,Q15382,Q9BZG1,Q86YB8,Q9BSR8,Q9Y3B3,Q96AA3,P37268,Q9BRR6,P27824,O76024,Q9UBV2,P67812,Q99735,O95197,P10321,Q8N511,P43307,P04035,Q9BQE5,Q96AG4,Q86YN1,O00461,P30519,Q9BUN8,Q99720,P09601,Q8N5M9,Q96G23,P27544,Q9Y282,Q6IAN0,Q15629,Q9H4A5,O15269,P24390,Q9NPR9,Q969V3,Q8N4V1,Q99442,P51648,O15027,Q9NQC3,Q9BV10,Q4ZIN3,Q6NUK...
Localization
GO Cellular component
msigdb_gocc
4,514,525,523,535,539,534,24,26,531,529,548,31,545,33,540,35,36,549,40,555,43,45,46,48,50,51,53,56,59,60,572,62,580,582,73,75,588,77,589,79,591,86,600,89,91,607,94,609,97,605,99,101,102,106,620,617,110,114,624,630,119,120,121,632,633,124,125,634,637,138,142,659,146,655,150,151,651,667,668,155,664,671,159,163,164,169,67...
1170,1213,2490,201,239,372,1551,2909,45,3071,2793,651,2026,1457,458,3631,736,634,1690,746,1630,1899,591,334,230,582,2325,504,2240,3485,243,2283,753,2529,720,3104,684,1401,2884,114,293,1379,106,1659,2854,101,3388,204,2130,1523,721,943,1078,351,159,439,975,529,1869,1318,1429,3074,1929,102,33,260,1633,181,2669,3439,2735,6...
0.2129676082349203,0.18366745927428121,-0.4611668784241816,1.7805289975127767,1.6226405617971547,1.21920071301935,-0.011395355835454363,-0.685395268863844,2.920564046857691,-0.8106229565179895,-0.6152759646849048,0.684682551459923,-0.24701667429505778,0.03434555447499574,1.0275779101847236,-2.929607055975441,0.57794661...
3,643
Inorganic ion transmembrane transport
57
134
3.569043
0.000358
Q96ES6,Q96GC9,P00403,P21796,Q9H4I9,O75964,P62258,P00846,P13073,P06576,O95202,Q7KZN9,Q9UDW1,Q8WWC4,P08195,P0DP25,P20674,Q06787,P21281,Q9NRA0,Q6P4Q7,Q9UJZ1,Q9UBX3,Q9UHG3,P00395,Q9NWR8,P62942,P22466,P16615,O14548,O43707,P20020,P08574,P05023,Q8N1S5,Q8N4V1,Q9UMX0,P98194,O75027,Q6KCM7,P05141,Q9HD20,P24539,Q9HC07,P56134,Q96HE...
Processes and pathways
GO Biological process
msigdb_gobp
130,259,133,9,10,12,776,15,149,530,152,153,27,666,161,795,541,797,294,303,691,827,58,186,819,581,319,65,317,451,828,831,830,829,76,77,734,846,597,342,842,94,475,224,861,483,613,250,238,500,371,372,768,244,122,508,509
372,1346,451,2239,828,3123,597,1023,1214,1660,1079,12,152,1870,819,133,15,1297,829,1100,842,3077,530,2405,1493,3171,161,830,795,977,945,508,149,317,3441,2071,2916,831,541,294,3632,3523,9,65,1174,475,1232,1104,3220,2887,2435,2293,1080,2918,613,873,1703,2742,1045,3199,1253,1148,860,509,1735,1388,1357,861,244,1217,2372,77...
1.21920071301935,0.09464742558718883,1.0397949556104586,-0.34465654335830465,0.46867841236197944,-0.8470088757604822,0.7889925013317961,0.3140906358105457,0.18366745927428121,-0.07308450629753695,0.27102098199975727,3.635267768351748,2.041502140292411,-0.16716107737328262,0.48247922194350323,2.175850808055284,3.5676938...
3,643
Primary mitochondrial disease
41
110
3.458323
0.000544
O75380,P00403,Q9NWS8,O43676,Q5XKP0,P00846,Q96IX5,Q9Y2R0,Q9BQT8,O14949,P13073,Q7KZN9,Q8IUX1,Q9NPL8,Q9P0J0,P20674,Q53H12,Q9BUB7,Q8NI60,Q86Y39,O43819,Q9H3H1,Q6DKK2,P39210,Q9UBX3,Q96CU9,Q7LG56,P03886,Q70HW3,Q9Y6M9,O60313,Q6P4A7,O95831,O95169,Q99797,P12235,Q9Y584,O75880,P0DJ07,Q96I36,Q9BRT2
Drugs and Diseases
Protein Atlas Disease involvement
protein_atlas_disease_involvement
635,133,528,13,141,15,658,17,279,21,149,153,277,411,289,541,165,425,423,44,300,562,173,432,58,66,453,72,88,215,345,477,355,616,235,508,111,368,116,247,644
857,1346,21,13,2327,300,345,1023,785,635,1121,1730,368,616,1594,355,819,133,15,72,1297,2329,830,3080,116,508,149,756,3035,541,1064,1232,3014,1828,432,2137,2332,1045,2138,3391,958,1668,2297,654,1462,1968,1840,894,1711,165,1111,1412,1413,799,2549,141,173,477,88,153,2551,453,44,917,277,899,1885,865,423,1203,2652,1542,66,2...
0.44095258539286264,0.09464742558718883,3.422104212978296,3.6218409135416008,-0.3776549171329734,1.4254643571680072,1.2890126041449141,0.3140906358105457,0.5236359569657166,0.7109834670817337,0.24208474921036938,-0.10423513187568594,1.2309114431358545,0.7501540898399927,-0.04213873900270941,1.2658620626092636,0.4824792...
3,643
Golgi membrane
71
174
3.448317
0.000564
P15291,Q8NF37,O95721,O95249,Q15382,L0R6Q1,Q8NBN3,Q15392,Q9Y3B3,P61026,Q8TB61,Q96S66,P78536,Q16739,O95197,P10321,Q9Y3E0,O60512,Q8NDZ4,O00461,Q8N4A0,Q9HD26,Q7LGA3,Q9Y282,Q9Y5Z9,Q9H4A5,Q99640,Q96L58,O15258,P40616,P48739,Q8IV08,Q969X5,P24390,Q8N4V1,O14653,Q8NCH0,Q10472,O15027,Q9NTJ5,Q9H7Z7,P35613,O75396,Q9BVK6,O43752,Q9HC0...
Localization
GO Cellular component
msigdb_gocc
637,258,646,260,514,266,142,272,539,655,150,668,412,162,33,540,506,293,422,45,176,563,560,60,316,580,445,701,447,318,452,454,455,73,77,458,80,339,591,731,340,217,721,609,720,224,97,605,99,612,356,233,102,486,232,230,617,752,502,500,623,114,241,242,372,493,504,120,121,122,253
266,372,45,1457,3574,458,591,447,230,1145,504,2240,623,2666,2529,720,612,114,293,2854,721,1270,102,33,260,646,2494,1026,3126,748,540,844,3198,637,2202,73,1322,97,1385,1910,217,1794,318,2136,1797,452,789,356,1253,1407,486,1148,1502,1356,3324,3557,1737,3606,1765,1912,2857,1279,655,1280,617,2744,1108,412,3507,2972,846,270...
1.5251418478775813,1.21920071301935,2.920564046857691,0.03434555447499574,-1.595762963282852,1.0275779101847236,0.801865710054151,1.0519791774245264,1.6546710303066048,0.22754892265502283,0.9411256311783628,-0.34465654335830465,0.7371343864831222,-0.5461685826019146,-0.47804647957846336,0.591424850029758,0.763136881820...
3,643
Oxidoreductase
43
126
3.264679
0.001096
Q9BY49,Q9UBM7,P00374,O75380,P00403,P14406,P49748,Q8TED1,Q86YB8,Q15392,P56556,Q15800,Q9UDW1,O43169,O43674,Q9NZ01,Q8N4Q0,O75438,Q9P0J0,P20674,P36551,O95168,O43819,P21912,O43175,O75845,Q14739,Q96CU9,O14548,Q7LG56,P03886,Q16850,Q9H7Z7,Q9Y6M9,P31350,O95831,Q96HE7,O15260,O95169,Q00796,O75880,Q14534,Q8N0U8
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
516,386,1,635,133,2,649,524,523,272,654,146,27,28,284,414,287,158,289,541,551,420,300,431,567,439,320,66,451,453,72,335,340,215,476,355,483,230,616,618,368,374,254
857,3071,1346,451,793,230,28,567,3010,284,2327,300,1521,1023,785,635,158,439,368,3438,1869,3452,420,616,355,841,3061,1,2196,819,133,72,1297,2796,2066,2572,1992,1905,663,977,2797,945,2247,3154,956,2,2886,756,2462,1103,541,431,2248,3608,2574,3014,2536,2942,758,3266,1828,476,2799,2366,551,2108,1911,3416,1665,3556,2702,649...
0.44095258539286264,-0.8106229565179895,0.09464742558718883,1.0397949556104586,0.5099577696894736,1.6546710303066048,3.1974548749844005,0.8402691890792825,-0.7565542021610706,1.4700401884505825,-0.3776549171329734,1.4254643571680072,0.0039012029953633324,0.3140906358105457,0.5236359569657166,0.7109834670817337,2.002346...
3,643
Outer membrane
47
101
3.242599
0.001184
Q9NS69,Q9UBM7,Q8N4H5,Q9Y3D6,Q9NX63,P21796,Q5XKP0,P45880,Q9BVC6,Q9HCL2,Q8N2A8,Q9NZJ7,O43169,Q13505,Q16891,Q9NX47,Q53H12,Q9Y512,P50402,Q8WY22,Q8IVP5,P30536,P52789,Q99720,P09601,Q9Y277,O00165,Q6UXV4,P50416,Q9Y6C9,P57105,O60313,Q9NZ45,O96008,Q15388,Q99623,Q9Y371,O00264,Q9NQZ5,Q9BUR5,Q8IWB1,Q9NUQ2,Q07820,O75431,Q9GZY8,Q9UKU...
Localization
GO Cellular component
msigdb_gocc
7,386,3,392,390,9,141,19,407,23,25,154,28,32,416,418,165,426,421,41,302,47,304,50,51,179,306,467,463,83,90,345,98,485,490,238,502,239,113,241,117,119,245,492,123,124,255
306,239,1551,3636,28,345,2884,1214,492,1901,1024,2735,485,1381,3078,2633,51,2069,2699,9,47,2074,2919,2800,2136,2137,19,421,463,304,2298,90,2299,245,629,32,2611,490,1801,1883,416,165,2471,141,678,1849,467,1007,302,117,2011,2711,1072,25,3,1471,2615,825,631,2013,41,3138,3490,2514,1157,505,681,951,238,50,812,241,407,255,15...
1.4030088099179048,1.6226405617971547,-0.011395355835454363,-5.352631459605619,3.1974548749844005,1.2890126041449141,-0.6677690785969682,0.18366745927428121,0.9535770922122667,-0.18302459062116297,0.3140906358105457,-0.5805974728701105,0.9783782010378161,0.07964458625645383,-0.8106229565179895,-0.5290467050709876,2.872...
3,643
Energy derivation by oxidation of organic compounds
39
137
3.221427
0.001276
O75380,P00403,P14406,P49748,O75964,O43676,P00846,P56556,O14949,P06576,P13073,Q7KZN9,Q9UDW1,O43674,O75438,P20674,O95168,O95167,O43819,P21912,Q9H3K2,Q15070,O14548,P31751,P03886,P04062,O96000,Q9BSK2,Q9Y6M9,Q6KCM7,P24539,Q9NZ45,P36542,O95169,O95139,P46020,P56385,P04637,Q9BRT2
Processes and pathways
GO Biological process
msigdb_gobp
635,133,2,649,12,13,15,654,21,530,149,153,27,284,158,541,420,171,300,431,183,67,451,325,72,461,338,214,215,342,475,98,613,616,240,628,244,507,644
857,1346,451,21,284,13,2327,300,1521,1023,785,1214,635,3402,158,1121,1928,2104,1079,12,240,171,420,616,1459,1594,338,819,133,15,72,1297,461,2796,507,843,530,1662,2068,2534,2329,830,663,2364,3172,977,806,1957,2797,149,3154,1320,2,2774,756,1103,2071,3035,541,1789,431,1064,475,1232,1198,3014,2435,2968,1828,1044,325,1080,1...
0.44095258539286264,0.09464742558718883,1.0397949556104586,3.422104212978296,1.4700401884505825,3.6218409135416008,-0.3776549171329734,1.4254643571680072,0.0039012029953633324,0.3140906358105457,0.5236359569657166,0.18366745927428121,0.7109834670817337,-1.1096773999925473,2.0023469353928545,0.24208474921036938,-0.19894...
3,643
Cation transport
73
181
3.119286
0.001813
Q96ES6,Q96GC9,P00403,P21796,Q9H4I9,O75964,P62258,O43772,P00846,O43808,Q9Y619,P05067,P14373,P13073,P06576,O95202,Q7KZN9,Q9UDW1,O76024,Q8WWC4,P08195,P30825,O75844,P0DP25,P20674,Q01650,Q06787,P21281,P30536,Q9NRA0,Q6P4Q7,Q9UJZ1,P00395,Q9NWR8,Q9UNH7,Q9HC21,P62942,P22466,P16615,O14548,O43707,P20020,Q9H9B4,P08574,P05023,Q8N1S...
Processes and pathways
GO Biological process
msigdb_gobp
130,259,133,9,10,12,776,270,15,393,273,394,653,149,530,152,153,27,529,666,161,672,159,795,541,37,797,294,47,303,691,827,819,581,323,322,319,65,317,451,828,831,717,830,829,76,77,78,711,333,734,846,597,342,88,92,94,475,224,483,613,363,250,751,238,500,371,372,768,244,122,508,127
372,1551,1346,451,3631,2239,1120,78,828,270,393,1401,3123,597,1023,1214,2102,1660,159,1079,12,529,152,1295,1870,819,133,15,2600,1297,2824,829,1100,394,842,3077,530,2405,1493,3079,3171,161,830,795,977,3376,945,508,149,1576,653,317,3441,1196,2071,2916,831,541,294,3632,3523,9,65,1174,475,1495,1232,1104,3220,2887,2435,47,2...
1.21920071301935,-0.011395355835454363,0.09464742558718883,1.0397949556104586,-2.929607055975441,-0.34465654335830465,0.24208474921036938,2.5556521085871906,0.46867841236197944,1.514175794039268,1.1720512731971409,0.06459351975889793,-0.8470088757604822,0.7889925013317961,0.3140906358105457,0.18366745927428121,-0.27934...
3,643
Transporter
106
225
3.110663
0.001867
Q9H2V7,P00846,Q9Y3B3,P06576,Q92973,Q01650,Q9BQE5,Q9UBX3,Q5SQN1,Q15070,P24390,Q8N1S5,Q7L0J3,Q9Y6C9,O75027,Q70HW3,Q6NUK4,Q8NEW0,Q9BVK6,Q13190,P36542,P61923,Q9Y584,P08183,O60499,O15400,Q9HD45,Q9P2W9,Q8N2H4,Q86VD7,Q96ES6,O95721,O43760,Q93050,Q8TB61,O95202,Q9NZJ7,P55735,Q96H78,P08195,P30825,Q8N1F7,Q8NI22,Q9Y5K8,P53985,Q9H2D...
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
526,15,539,530,533,37,40,58,571,67,73,76,594,83,597,88,91,92,609,605,613,617,111,625,114,622,115,120,121,127,130,646,136,143,150,152,154,155,156,161,672,675,164,697,172,178,686,703,195,718,717,212,214,720,224,742,736,751,750,772,249,768,244,753,260,268,270,273,279,789,802,294,823,817,822,821,315,322,317,831,829,848,846...
3070,2882,372,2358,3573,2793,1457,3574,458,736,3425,622,817,753,720,136,270,393,114,1868,1062,2242,686,2854,597,3011,1928,1079,1929,152,260,1633,2669,3439,908,646,485,15,944,829,1100,842,530,625,161,1575,2434,844,3062,508,462,750,317,3282,2071,831,294,3632,1174,73,475,1232,1382,947,672,1874,1910,613,2076,1703,821,1797,...
-0.8106229565179895,-0.6677690785969682,1.21920071301935,-0.3942404427457948,-1.595762963282852,-0.6152759646849048,0.03434555447499574,-1.595762963282852,1.0275779101847236,0.5779466188099379,-1.1483895409000466,0.7371343864831222,0.48247922194350323,0.5508712677221353,0.591424850029758,2.1378851132977377,1.5141757940...
3,643
Ion transport
107
240
3.105375
0.0019
P21796,Q9H4I9,O75964,P00846,P45880,P06576,Q9UDW1,O76024,P20674,Q01650,P30536,Q9HD26,Q9UBX3,Q9NWR8,P22466,P04083,Q8N1S5,Q8N4V1,O15173,Q7L0J3,O75027,Q70HW3,Q8NEW0,Q9HD20,P36542,Q8NE01,P08183,Q8IUH4,Q86VD7,Q96ES6,P00403,P14373,P13073,Q8TB61,O95202,Q7KZN9,Q96S66,Q9NZJ7,Q8WWC4,P08195,P30825,O75844,P53985,Q6P4Q7,Q9H2D1,Q9Y27...
Processes and pathways
GO Biological process
msigdb_gobp
9,10,12,15,19,530,27,529,541,37,47,563,58,581,65,574,76,77,78,594,597,88,92,94,613,614,625,122,127,130,133,653,149,150,152,153,668,154,666,161,672,159,172,691,178,179,186,718,717,711,734,219,224,751,238,748,768,244,250,755,259,776,270,273,279,795,797,294,303,827,817,821,819,321,323,322,319,317,828,831,830,829,332,333,8...
3057,372,1551,1346,451,3631,2239,1490,1120,78,817,491,828,270,393,1401,3123,219,597,3030,1023,1214,2102,1660,1928,159,975,1079,12,529,152,1295,908,1870,485,819,133,15,2600,1297,574,2824,944,829,1100,394,842,3077,530,2405,1493,3079,332,3171,625,161,830,748,795,977,2069,844,3376,945,508,462,149,1576,755,653,317,3441,1196...
-0.7925324929496625,1.21920071301935,-0.011395355835454363,0.09464742558718883,1.0397949556104586,-2.929607055975441,-0.34465654335830465,0.019148074018054462,0.24208474921036938,2.5556521085871906,0.48247922194350323,0.9535770922122667,0.46867841236197944,1.514175794039268,1.1720512731971409,0.06459351975889793,-0.847...
3,643
The citric acid tca cycle and respiratory electron transport
39
110
2.911875
0.003593
O75380,P00403,P21796,O75964,O43676,P00846,P56556,O14949,P06576,P13073,Q8IUX1,Q9NPL8,Q9UDW1,O43674,O75438,Q9P0J0,P20674,O95168,O95167,Q86Y39,O43819,P53985,P21912,P09669,O14548,Q04760,Q9P0J1,P03886,O96000,Q8N8Q8,Q9Y6M9,P35613,P24539,P36542,O95169,O95139,O75880,P56385,Q96I36
Processes and pathways
Reactome Pathways
msigdb_reactome
635,133,9,12,13,15,654,21,530,149,277,411,27,284,158,289,541,420,171,44,300,172,431,568,451,584,200,72,338,84,215,217,475,613,616,240,368,244,247
857,2694,1346,451,21,284,13,2327,3103,300,1521,1023,785,635,3402,158,1121,368,1079,12,240,171,420,616,1459,1594,908,338,3061,819,133,15,72,1297,530,1992,2068,2329,830,663,568,3172,977,806,149,3154,756,1103,2071,3035,541,9,431,1064,910,475,1232,3014,1828,1080,217,613,2331,2108,3416,2137,1045,3199,1963,2537,3391,3229,123...
0.44095258539286264,-0.5633520351399934,0.09464742558718883,1.0397949556104586,3.422104212978296,1.4700401884505825,3.6218409135416008,-0.3776549171329734,-0.8287815921428723,1.4254643571680072,0.0039012029953633324,0.3140906358105457,0.5236359569657166,0.7109834670817337,-1.1096773999925473,2.0023469353928545,0.242084...
3,643
Increased serum lactate
33
118
2.905051
0.003672
P00403,Q9NWS8,Q5XKP0,P00846,Q5JRX3,O14949,P13073,Q7KZN9,Q8IUX1,Q9P0J0,Q53H12,Q9BUB7,Q8NI60,Q86Y39,O43819,P21912,Q9UBX3,Q96CU9,Q7LG56,Q9P0J1,P03886,Q70HW3,Q9Y6M9,Q6P4A7,O95831,Q9NVI7,Q99797,Q9Y584,O75880,P0DJ07,Q96I36,P12235,Q86VD7
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
133,528,141,15,274,21,149,153,277,289,165,425,423,44,300,431,58,66,453,200,72,88,215,477,355,234,235,111,368,116,247,508,127
857,2694,1551,1346,21,2327,300,1023,785,1660,1121,888,368,616,1594,355,3061,819,133,3197,15,72,1297,1662,2329,830,3080,663,116,3639,508,149,756,3035,541,431,1064,3283,3014,3499,1828,978,3505,2369,3416,2137,2332,2138,3391,3178,958,1668,2297,3017,2677,1462,2000,1968,2110,2542,3040,894,2510,1711,1128,165,1111,274,1412,176...
0.44095258539286264,-0.5633520351399934,-0.011395355835454363,0.09464742558718883,3.422104212978296,-0.3776549171329734,1.4254643571680072,0.3140906358105457,0.5236359569657166,-0.07308450629753695,0.24208474921036938,0.413059611298448,1.2309114431358545,0.7501540898399927,-0.04213873900270941,1.2658620626092636,-0.792...
3,643
Transport of small molecules
72
171
2.833349
0.004606
P28074,P21796,Q9H4I9,Q93050,P45880,Q8TB61,P25787,O95202,Q9H300,Q8WWC4,Q9UBV2,P08195,P07237,P30825,Q01650,P21281,Q9Y5K8,P30519,P53985,Q9BUN8,Q9BU23,Q9UJZ1,P09601,Q9Y277,O00231,O15439,O00487,P28070,Q9UBX3,P61289,Q9NWR8,P10644,P36404,P16615,Q8WTV0,P20020,P05023,Q9UBI6,Q8N4V1,Q96TA2,P35232,P02654,Q9UL46,P98194,P12236,O7502...
Processes and pathways
Reactome Pathways
msigdb_reactome
757,9,10,143,19,150,405,152,283,666,548,161,408,672,37,294,697,46,172,48,437,827,51,179,558,817,683,569,58,440,581,699,832,317,198,831,829,856,77,852,708,209,733,846,462,597,844,88,842,472,217,723,92,722,94,95,858,363,235,108,238,508,625,249,372,630,768,493,633,377,378,509
558,3337,2236,372,683,1898,858,817,1317,597,1660,943,2065,3438,1429,3340,152,3473,3629,209,2600,944,829,1100,842,1492,408,625,161,1575,51,699,844,508,462,1826,317,3441,1932,831,2032,722,294,3632,1789,9,1174,723,405,2072,2738,1104,1460,569,95,757,1382,46,2293,672,1874,708,978,1028,217,3015,832,873,3638,1703,377,2920,203...
0.8529989184041223,-1.0331656198140247,-0.34465654335830465,1.21920071301935,0.6316243203959113,-0.18302459062116297,0.44095258539286264,0.48247922194350323,0.10960232235260665,0.7889925013317961,-0.07308450629753695,0.37090264942965717,-0.26315089466392805,-1.1678616368145254,0.04949393902221869,-1.0331656198140247,2....
3,643
Inner mitochondrial membrane protein complex
50
90
2.811827
0.004926
O60830,Q99595,O75380,Q9Y5J7,P00403,P14406,Q9NX63,Q9H4I9,O75964,O43676,Q5XKP0,P00846,Q96IX5,P56378,O14949,P06576,P13073,Q9UDW1,O43674,Q13505,O75438,Q9P0J0,Q16891,P20674,Q53H12,Q9Y512,O95168,O95167,Q86Y39,P21912,P09669,Q9NWR8,Q96CU9,O14548,Q9Y5J6,P03886,Q6UXV4,O96000,P12236,Q9Y6M9,O14925,P24539,P36542,O95169,Q99623,Q9Y58...
Localization
GO Cellular component
msigdb_gocc
0,5,635,388,133,2,390,10,12,13,141,15,658,145,21,530,149,27,284,32,158,289,416,541,165,426,420,171,44,431,568,581,66,451,457,72,467,338,462,215,216,475,613,616,238,111,240,241,492,244
857,1346,451,216,21,284,13,2327,0,1023,785,635,492,158,1121,1079,12,240,171,420,616,1459,1594,338,819,133,15,72,1297,530,830,568,977,462,149,2,756,1103,2071,3035,541,431,1064,475,1232,3014,1828,1080,708,613,2800,1045,3199,3391,861,145,244,654,32,1611,1711,416,1128,165,141,467,44,918,1473,66,658,5,238,1052,241,10,1372,1...
0.44095258539286264,0.09464742558718883,1.0397949556104586,1.7075469085996575,3.422104212978296,1.4700401884505825,3.6218409135416008,-0.3776549171329734,3.8634295457323278,0.3140906358105457,0.5236359569657166,0.7109834670817337,0.9535770922122667,2.0023469353928545,0.24208474921036938,0.27102098199975727,3.6352677683...
3,643