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A q from a tribal area of jharkhand repos with fever for last 3days Peripheral blood is collected and stained with Giemsa A diagnosisof malaria is made The smear is shown in the fig What is the likely cause
REF : ANANTHANARYANA MICROBIOLOGY
1
P falciparum
P Vivax
P Malariae
P Ovale
Microbiology
general microbiology
80a60536-1dc8-4b86-b676-a6b9fcdbfb0b
single
Tom-smith arthritis results from
(Septic arthritis) (39- Apley'8th)* Septic Arthritis in Infancy (TOM-SMITH-ARTHRITS)* The head of the femur is cartilaginous and is rapidly and completely destroyed by pyogenic process* Affected leg is shorter and hip movements are increased in all directions* Telescopy test is positive* X-ray complete absence of the h...
3
Rheumatoid arthritis
Osteo arthritis
Septic arthritis
Garre's osteomyelitis
Orthopaedics
Arthritis
fe640382-4f06-4181-9eb7-4675af6efd19
single
Most common cause of fracture of roof of orbit
"Orbital roof fracture should be suspected in any child presenting with blunt injury to the brow or forehead with subsequent development of a hematoma of the upper lid in the hours following injury ". — Pediatric ophthalmology
3
Blow on back of head
Blow on parietal bone
Blow on the forehead
Blow on the upper jaw
Ophthalmology
null
bfd184e0-f5ea-49bc-94c1-ade8da7c1b6d
single
Teeth that erupt within 30 days of birth are called:
null
1
Neonatal
Natal
Primary
Prenatal
Pathology
null
4b595401-a433-4052-ac0d-6b6a369ac32a
multi
Which is not a neuronal tumour
The four major classes of brain tumors are: 1. Gliomas Astrocytoma * Pleomorphic xanthoastrocytoma * Brainstem glioma * Pilocytic astrocytoma * Fibrillary (diffuse) astrocytomas * Glioblastoma * Oligodendroglioma * Ependymoma 2. Neuronal tumors * Ganglion cell tumors * Gangliocytoma * Ganglioglioma * Dysembryoplastic n...
1
Ependymoma
Neuroblastoma
Gangliocytoma
Ganglioglioma
Pathology
Nervous system
b42c7989-889a-49a5-aca8-82acad9c37f5
single
Most common immediate complication of splenctomy:
When splenectomy is performed, we are prone to injure the tail of pancreas, there is a high chance of Acute pancreatitis to occur or a duct maybecut leading to fistula. Sometimes, the blood may be collected below the diaphragm which may lead to sub-diaphragmatic abscess. Since, the spleen is in relation to the left dom...
1
Hemorrhage
Fistula
Bleeing from gastric mucosa
Pancreatitis
Surgery
FMGE 2018
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single
All of the following are excitatory neurotransmitters except
GABA is the major inhibitory mediator in the brain, including being responsible for presynaptic inhibition. GABA, which exists as b-aminobutyrate in the body fluidsReference: Ganong review of medical physiology 23rd edition Page no; 141
1
Gamma-aminobutyric acid
Acetylcholine
Dopamine
Serotomin
Physiology
Nervous system
062899e0-f386-4cb3-a8fb-08ce73cd5864
multi
A case of young patient presents to you with knee pain, irritability and gum bleeding. Upon x-ray of leg, cortex is significantly thin with a white line at the metaphysis. What could be possible cause:
Ans. (c) ScurvyRef: Maheshwari 5th ed. 1315Scurvy causes failure of collagen synthesis and osteoid formation. It clinically presents with:* Irritability* Gum bleeding* Pseudoparalysis (due to subperiosteal haemorrhage)* Anemia and beading of costo-chondral junction. Radiological features are: Frenkels line (dense line ...
3
Fluorosis
Rickets
Scurvy
Caffey's disease
Orthopaedics
Scurvy
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single
Seen in trachoma are/is:
A i.e. Papillary hyperophy; B i.e. Follicles; C i.e. Panus formation
4
Papillary hyperophy
Follicles
Panus formation
All
Ophthalmology
null
ef45fef4-f784-427e-9a80-2bba548a180a
multi
First line treatment of T315I mutation in CML management is?
T315I mutation is a mutation in the critical BCR-ABL kinase in the ATP-binding pocket This prevents imatinib binding and hence leads to resistance to imatinib, nilotinib, bosutinib, and dasatinib. Only drug effective for T315I mutation CML = Ponatinib. Otherwise DOC CML= Imatinib. DOC for Imatinib resistant CML = Bosut...
3
Bosutinib
Tofacitinib
Ponatinib
Nilotinib
Medicine
CLL & CML
20442569-e3fd-409b-93f9-d92923cd6b15
single
Horner trantas spot is seen in?
Vernal REF: Khurana 4th ed p-451, Yanoff & Ducker-ophthalmology 2nd edition page 407 A characteristic manifestation of limbal vernal conjunctivitis is the presence of Horner-Trantas dots, which are white, chalk-like dots composed of eosinophils and epithelial debris.
3
Trachoma
Phlytenular Kerato conjunctivitis
Vernal Kerato conjunctivitis
Giant Papillary conjunctivitis
Ophthalmology
null
4337f72f-515e-4118-a504-bae730a1ff58
single
The blood-brain barrier is formed by
There are three types of microglia: oligodendrocytes, Schwann cells, and astrocytes. Oligodendrocytes and Schwann cells are involved in myelin formation around axons in the CNS and peripheral nervous system, respectively. Astrocytes, which are found throughout the brain, are fuher subdivided into two groups. Fibrous as...
2
Oligodendrocytes
Astrocytes
Microglial cells
Schwann cells
Biochemistry
Enzymes
b136d913-241c-4bcf-842a-d0ab1260673a
single
Following are the laboratory tests for the diagnosis of vestibular dysfunction except
Gelle&;s test compares the intensity of bone-conducted tuning fork sound without and with raising pressure on the tympanic membrane with Siegel&;s speculum. It&;s a test of bone conduction and examines the effect of increased air pressure in ear canal on the hearing. (Ref: Diseases of EAR, NOSE and THROAT by PL DHINGRA...
4
Electronystagmography
Optokinetic test
Galvanic test
Gelle's test
ENT
Ear
3f93b40e-b7ee-4cb9-8bea-e6411d6bef0f
multi
Gastric acid secretion is stimulated by all except-
Ans. is 'd' i.e., Somatostatin o There are following phases of gastric acid secretion : -The cephalic phase Just as salivary secretion may start before food enters the mouth, gastric secretion is also intitiated before food enters the stomach . Sight, smell or even thought of food stimulate gastric acid secretion. It i...
4
Gastricdistension
Gastrin
Smell of food
Somatostatin
Physiology
Secretory Functions of the Alimentary Tract
f4388694-90f7-4b0f-8ac4-01ce87faa651
multi
Suture present between parietal & occipital bones is
The lambdoid suture lies between the occipital bone and the two parietal bones. Sutural bones are common along this suture. Lambdoid sutures are usually visible clearly. The lambdoid suture traverses the posteriormost pa of the skull. Ref: BD Chaurasia's HUMAN ANATOMY, Volume 3, 4th edition.
1
Lambdoid suture
Saggital suture
Coronal suture
Metopian suture
Anatomy
Head and neck
9b0bec46-792b-4995-befa-e3c458c0af86
single
Cell volume & shape is maintained by
Gibbs-Donnan effect---there are more osmotically active paicles in the cells than the interstitial fluid. This would make them swell and eventually rupture, but prevented by operation of Na+-K+ pump which produces net movement of positive charge out of the cell and keeps the inside a.d outside of the cell in osmotic eq...
2
Goldman effect
Gibbs - Donnan effect
Singer's effect
None
Physiology
General physiology
996181fa-6045-450c-a080-bdfb109535a8
multi
The most common site of enlargement of the lymph nodes in Hodgkin's lymphoma is
In about 50% of patients who have both Hodgkin's and non-Hodgkin's lymphoma, the mediastinum may be the primary site." Ref : Schwaz 9/e p575
3
Cervical
Axillary
Mediastinal
Abdominal
Surgery
Vascular surgery
e3c8ba80-237f-4457-8d59-b720501d070c
single
Kaposi sarcoma occurs with infection due to -
null
1
HHV8
HHV4
HHV2
HHV1
Pathology
null
e8e3e6be-e6f7-4c38-812f-14bf3d9c3bee
single
The posterior focal point of the reduced eye situated on the retina is how many millimetre behind the anterior surface of cornea:
Ans. 24.4 mm
2
22.9 mm
24.4 mm
23 mm
21 mm
Ophthalmology
null
f401cdfe-1c00-429d-8672-c0fb52575f79
single
Microangiopathic hemolytic anaemia (MAHA) is a component of all of the following, except:
- Paroxysmal nocturnal hemoglobinuria (PNH): Results from acquired mutations in PIGA gene leading to deficiency of GPI-linked proteins in membrane of blood cells. Red cells deficient in GPI-linked factors are abnormally susceptible to lysis or injury by complement. This manifests as intravascular hemolysis, which is ca...
4
Thrombotic thrombocytopenic purpura (TTP)
Hemolytic uremic syndrome (HUS)
Hemolysis with elevated liver enzymes and low platelet (HELLP) syndrome
Paroxysmal nocturnal hemoglobinuria
Pathology
Hemolytic Anemias: Basic concepts and classification
87475161-a5e0-4f0e-87c0-af0c849e4448
multi
Testicular tumour most sensitive to radiation is?
Ans. is 'd' i.e., Seminoma
4
Teratoma
Lymphoma
Mixed germ cell tumor
Seminoma
Surgery
null
7378bcf0-50dd-4e42-8479-88f63b48c3b9
single
All of the following statements about Pseudohypoparathyroidism are true, except -
null
1
↓Serum PTH
↓ Serum calcium
↑ Serum phosphate
Albright's hereditary osteodystrophy
Medicine
null
5dd30015-5b7e-489d-9241-d31ab008c2ab
multi
Lysogenic conversion is -
New propeies in the bacterium is due to integration of phage genome REF:MICROBIOLOGY ANANTHA NARAYANAN NINTH EDITION PAGE.60
1
New propeies in a bacterium due to integration of phage genome
Transfer of DNA from one bacterium to another by a bacteriophage
Transfer of free DNA
Transfer of genome during physical contact
Microbiology
Virology
acf5ccc7-76b0-4d41-bfe1-94836d9951cb
single
All of the following are methods of health promotion except-
Ans. is 'a' i.e., Immunization o All the given options are examples of primary prevention. o Primary prevention has two main components :- i) Health promotion ii) Specific protection Mode of intervention of Primary prevention Health promotion Specific protection Health education 1. Immunization Environmental modificati...
1
Immunization
Nutritional changes
Behavioral changes
Health education
Social & Preventive Medicine
null
48e2f07f-f43a-40d3-aad4-4a13f9cf9240
multi
Treatment of choice in prenatal congenital adrenal hyperplasia -
Ans-B i.e., DexamethasonePrenatal treatment of congenital adrenal hyperplasia consists of maternal administration of dexamethasone which is not degraded by the placenta and crosses into the fetal circulation.The rationale for prenatal therapy is that suppression of pituitary ACTH secretion by exogenous glucocorticoid w...
2
Hydrocortisone
Dexamethasone
Betamethasone
Prednisolone
Unknown
null
a944d313-ee83-4e21-a2a5-2a5bb3f3e060
single
In patients with anterior uveitis, decrease in vision due to posterior segment involvement can occur because of –
"Cystoid macular edema is a common cause of visual loss in patients with uveitis and may be observed in the setting of severe anterior or intermediate uveitis. Long-standing or recurrent macular edema can cause permanent loss of vision due to cystoid degeneration". - Lange Ophthalmology
4
Visual floaters
Inflammatory disc edema
Exudative retinal detachment
CME
Ophthalmology
null
a7cb3e8d-8707-4305-88e8-da5e751704e2
single
Which of the following amino acid is excreted in urine in maple syrup urine disease
In maple syrup urine disease there is the excretion of branched chain amino acids (isoleucine, leucine, valine) and their keto acids (α -keto β-methyl valerate, α-ketoisocaproate, α-ketoisovalerate) in the urine.
3
Tryptophan
Phenylalanine
Leucine
Arginine
Biochemistry
null
71ad3813-7d19-4042-9fd5-bd00b4c2cdba
single
Single gene defect causing multiple unrelated problems –
Pleiotropy occurs when a mutation in a single gene produces effects on more than one characteristic, that causes multiple mutant phenotypes. In humans, this phenomenon is most obvious when mutations in single genes cause diseases with seemingly unrelated symptoms. Some examples of this phenomenon are: Transcription f...
1
Pleiotropism
Pseudodominance
Penetrance
Anticipation
Pediatrics
null
7b37795d-241f-4fc9-9661-21e6b8eda33f
single
What does cardiac polyp means -
. Fibrinous clot
4
Acute infarct
Cardiac aneurysm
Benign tumour
Fibrinous clot
Pathology
null
21930d6a-b1ed-4bc2-bf92-cb6ecd7ecac4
single
Leading questions are permitted only in -
In cross-examination, the witness is questioned by the lawyer for the opposite pay. Leading questions are permissible during cross-examination. In examination-in-chief leading, questions are not allowed except in those cases, where the judge is satisfied that a witness is hostile. examination in chief and re-examinatio...
2
Examination in chief
Cross Examination
Dying declaration
Re-examination
Forensic Medicine
Medico legal procedures
19a6f511-0cef-400b-8e09-fea92c81cca1
single
Relative risk of 5 means -
Ans. is 'c' i.e., Incidence of disease is 5 times higher in exposed group * Relative risk is a direct measure of the strength of association between suspected cause and effect. For example a relative risk of 2 means that the incidence rate is 2 times higher in the exposed group as compared with unexposed - i.e., a 100%...
3
50% of disease among exposed is due to exposuse to risk factor
50% of disease is due to risk factors
Incidence of disease is 5 times higher in exposed group
Incidence of disease is 50% more in exposed group
Social & Preventive Medicine
Epidemiology
5b797d83-adbb-4674-b153-852ba4a67738
single
Low glycemic index is classified as value less than:
Concept of glycemic index has utility in management of diabetes and obesity. Classification GI range Example Low GI 55 or less Most fruits and vegetables except potatoes and water melon, pasta beans, lentils Medium GI 56-69 Sucrose, brown rice, basmati rice High GI 70 or more Corn flakes, white bread, candy bar Ref: Pa...
3
25
45
55
65
Social & Preventive Medicine
null
64cdae09-be6d-42d6-990a-d170d4225895
single
Periodontal surgery is most difficult to carry out in 2nd molar distally due to:
null
3
Lack of sufficient attached gingiva.
Presence of bulbous fibrous tissue over tuberosity and retromolar pad.
Both
None
Dental
null
b14ad421-50b6-48d5-a31c-2615c7870417
multi
Iron deficiency is best demonstrated by:
Ans b (Se Ferritin)Ref: Davidson, 21 edpg. 1018Ferritin (n = 50 - 200 microg//)A measure of iron stores in the tissue and is the single best test to confirm iron deficiency Less than normal value of Se. ferritin is seen in:1. Iron deficiency2. Hypothyroidism3. Vitamin c deficiency Raised Se.ferritin value is seen in:1....
2
RDW
S. ferritin
BM examination
d.......
Medicine
Blood
2f85150c-3de8-4bd4-a62e-58d88d4475bc
single
Taurodontism is seen in which race
TAURODONTISM - Bull tooth; in mongoloids Pulp cavity of molars is wide and deep Roots are fused and bent
1
Mongoloids
Caucasian
Negros
None of the above
Forensic Medicine
Human identification
a0285952-d67a-4263-87ae-b084b122f009
multi
An investigator finds out that 5 independent factors influence the occurrence of a disease. Comparison of multiple factors that are responsible for the disease can be assessed by:
ANOVA: Analysis of variance is a parametric test used for polyotomous independent variable Chi-square test: is non-parametric test used for testing association between 2 or more qualitative variables Multiple linear regression: Is used if the target variables are dimensional having multiple possible values Multiple log...
4
ANOVA
Multiple linear regression
Chi-square test
Multiple logistic regression
Social & Preventive Medicine
Statistical Tests
60ab72e7-01f5-4f63-abf2-0724dac85445
single
Fine voluntary movements are transmitted by
(A) Lateral corticospinal tract > The nerve fibers that pass from the motor cortex to the cranial nerve nuclei form the corticobulbar tract. The nerve fibers that cross the midline in the medullary pyramids and form the lateral corticospinal tract make up about 80% of the fibers in the corticospinal pathway.> The remai...
1
Lateral corticospinal tract
Dorsal column
Anterior horn
Spinothalamic tract
Physiology
Nervous System
4b68dc66-44a2-494c-b9d6-2449ed9b068e
single
A 9 year old girl presents with menarche. History reveals thelarche at the age of 7 years and adrenarche at the age of 8 years- the M/C cause of this condition in girls is:
null
1
Idiopathic
Gonadal tumor
Mc cure albright syndrome
Hypothyroidism
Gynaecology & Obstetrics
null
c4192336-c955-4b5d-9016-e7e7e5d36510
single
sho acting acting beta 2 agonist
sho-acting beta2 agonists- salbutamol., terbutaline, pirbuterol long-acting- salmeterol, formoterol, clenbuterol ref kd Tripathi 8th ed
3
Formoterol
Isoprenaline
Salbutamol
salmeterol
Pharmacology
Respiratory system
372e2a07-8eb6-4190-98a9-b126c038eba3
single
EMA - CO regimen for treatment of choriocarcinoma includes all except
EMACO ⇒ Etoposide Methotrexate Actinomycin Cyclophosphamide Oncovin.
2
Etoposide
Cisplatin
Methotrexate
Actinomycin - D
Gynaecology & Obstetrics
null
b0b7df6c-e7ad-4e30-be19-bedbd14faed0
multi
The coagulation profile in a 13–year old girl with Menorrhagia having von Willebrand's disease is –
Von Willebrand's factor acts as a plasma carrier of factor VIII and circulates in the blood as factor VIII-VWF complex. Its deficiency, therefore, impairs the intrinsic pathway of coagulation and prolongs the PTT as the intrinsic pathway of coagulation remains unimpaired, PT is not altered. i) Bleeding time It is a n...
1
Isolated prolonged PTT with a nonnal PT
Isolated prolonged PT with a normal PTT
Prolongation of both PT and PTT
Prolongation of thrombin time
Pediatrics
null
98105d24-8ca4-4885-b354-63f7c600b17a
multi
Superior pancreaticoduodenal aery is a branch of?
Ans. is 'c' i.e., Gastroduodenal aeryGastroduodenal aery gives following branches :-Right gastroepiploic aerySuperior pancreaticoduodenal aery
3
Hepatic aery
Splenic aery
Gastroduodenal aery
Inferior mesenteric aery
Anatomy
null
6dc02852-bf7c-4410-be7d-82dafacb96bc
single
Echocardiography can detect pericardial effusion as little as:
Ans.
1
15 ml
100 ml
150 ml
200 ml
Radiology
null
e1c714bf-a740-428e-a83c-795d95aef306
single
SUPAR is a blood marker for
FSGS - supar. Mbranous  nephropathy - M - PLA2.
3
Minimal change disease
Membranous nephropathy
Focal segmental Glomerulo sclerosis
All the above
Medicine
null
d43f5bb9-0fde-4a35-a215-c67f8cd33773
multi
What is true about adductors of thigh -
Ans. is'd'i.e., Adductor magnus is the largest muscleIschial head of adductor magnus is a hamstring muscle (not adductor).Ischial head of adductor magnus originates from inferolateral aspect of Ischial tuberosity (not from adductor tubercle).Main aery of adductor (medial) compament of thigh is obturator aery (not profu...
4
Ischial head of adductor magnus is an adductor
Profunda femoris aery is the main blood supply
Ischial head of adductor magnus originates from adductor tubercle
Adductor magnus is the largest muscle
Anatomy
null
910570a4-b093-4c66-8003-8b90a3224a89
multi
Mycoplasma is intrinsically resistant to:
Ref. Robbins Pathology. 9th edition. Page. 1375   Mycoplasma Smallest extracellular bacteria. Lack a cell wall; are very flexible and able to pass through filters which are 0.4 microns and which stop most bacteria. 
 Contain sterols in their cell membrane; however, they cannot synthesize sterols so mycoplasmas acquire...
2
Aminogloycosides
Ceftazidime
Macrolides
Doxycycline
Unknown
null
d27a4e16-ba43-40ad-8416-3dd86764a892
multi
Chronic adrenal insufficiency is characterized by all of the following except-
In contrast in Adrenal insufficiency weight loss occurs Ref - Davidson's medicine 23e p672 , ( Harrison 17 pg 2263)
3
Excess pigmentation
Asthenia
Weight gain
Hypoglycemic episodes
Medicine
Endocrinology
92b22c80-d30e-446c-b97f-356d7aa60263
multi
A dental bur cuts the tooth structure more effectively when rake angle of bur is
null
1
Positive
Negative
Radial
None of the above
Dental
null
4e414275-8116-49cf-ac1a-3d3a56331815
multi
Provisions of free medical care to the people at government expense is known as -
State medicine. : administration and control by the national government of medical and hospital services provided to the whole population and paid for out of funds raised by taxation. Ref: 25th edition, Park's Textbook of Preventive and Social Medicine, Page no. 10
1
State medicine
Social therapy
Social medicine
Preventive medicine
Social & Preventive Medicine
Concept of health and disease
75b1deff-c4c9-452c-8e79-43368ceeb92d
single
Growth Hormone may be beneficial in the following, except:
Growth hormone is effective in accelerating the growth rate in children with constitutional growth delay. It increases the calcium absorption in the gastrointestinal tract and has a positive effect on osteogenesis; it may be of use in treatment of osteoporosis and non-healing fractures. In panhypopituitarism, there is ...
3
In children with constitutional growth delay.
In treatment of osteoporosis.
Laron type dwarfism.
Panhypopituitarism.
Pharmacology
null
414a36e6-2dc9-4dea-9b13-413e3b504a26
multi
Inulin is a polymer of
null
1
Fructose
Glucose
Galactose
Inulinose
Biochemistry
null
f5f1ac4f-a5a7-40d1-93b8-c265afb4706b
single
Cephalic vein drains into -
Ans. is 'c' i.e., Axillary vein Veins of upper limbo Cephalic vein is the paraxial vein of upper limb (like great saphenous vein of lower limb). It begins from the lateral end of dorsal venous arch. It is accompanied by lateral cutaneous nerve of forearm and terminal part of radial nerve.o Basilic vein is the postaxial...
3
Brachial vein
Subclavian vein
Axillary vein
IVC
Anatomy
Upper Extremity
58846f25-9051-40c6-a826-43d7f27ff837
single
In accidental hemorrhage, TOC:
Ans. is c, i.e. Simultaneous emptying of uterus and blood transfusionRef: Williams Obs 23/e. p 767: Dutta Obs. 7/e, p 257, 258; COGDT 10/e, p 333The basic principle in the management of abruptio is termination of pregnancy along with correction of hypovolemia and restoration of blood loss."With massive external bleedin...
3
Induction of labor
Rx of hypofibrinogenemia then blood transfusion
Simultaneous emptying of uterus and blood transfusion
Wait and watch
Gynaecology & Obstetrics
Antepartum Haemorrhage
104861eb-7002-4063-9b42-2618e01da506
single
Calcium channel blocker with maximum effect on conduction in hea is:
Verapamil is phenylalkylamine which depresses the SA node and slows AV conduction. Others are less potent. But verapamil can cause constipation It is class 4 antiarrhythmic drug REF.Essentials of Pharmacology KD Tripathi 8th ed.
4
Phenylamine
Nifedipine
Diltiazem
Verapamil
Pharmacology
Cardiovascular system
cc0f31c7-9abd-421a-b1d6-20b95fd03be8
single
Most probable diagnosis in a newborn baby with regurgitation of feeds and continuous drooling of saliva is:
Continuous drooling of saliva indicates no communication of Esophagus distally - esophageal atresia. Type E is also known as H shaped Fistula Least Common- Type D Classification of TEF Type A: Atresia only (6%) Type B: Atresia with proximal TEF (2%) Type C: Atresia with distal TEF (85%): Most common Type D: Atresia wit...
1
Esophageal atresia
Diffuse esophageal spasm
Achalasia cardia
Zenker's diveiculum
Surgery
DNB 2018
2e53d16c-97bc-4c1a-81e0-065e355883e8
single
A 68-year-old patient postoperative from thyroidectomy presents with muscle cramps; Chvostek's and Trousseau's signs are noted on examination.
Ans. (a) Prolonged QT interval.The rate is bradycardic at 54 beats/min. Ihe rhythm is regular with a narrow QRS and normal-appearing sinus P waves are seen. Axis is normal.The QT interval is very prolonged to more than 600 milliseconds with a long, isoelectric ST segment (best seen in lead V6) and T-wave inversions in ...
1
Prolonged QT interval
Short QT interval
ST elevation
ST depression
Unknown
null
44cc1f4b-4341-4b7c-bd55-a4a76a72d1a5
single
Methyl xanthines acts on
(Adenosine receptors) (202-3-KDT) (220-KDT 6th)Mechanism of action of Methylxanthines - Three distinct cellular actions(a) Release of Ca++ from sarcoplasmic reticulum especially in skeletal and cardiac muscle.(b) Inhibition of phosphodiesterase which degrades cyclic nucleotides intracellularly.ATPorGTPAdenylcyclase----...
2
Histamine receptors
Adenosine receptors
Mast cells
Cholinergic receptors
Pharmacology
Asthma
5925014d-c6a4-47e8-a580-68fefdc68152
single
Which one of the following is characteristic of tubercu otitis media;
Ans. (b) Multiple perforation of pars tensaRef: Dhingra's ENT 5ht ed. / 83Clinical features of Tubercular otitis media:# Painless foul smelling ear discharge: very characteristic finding.# Perforation: multiple perforations usually 2-3 on pars tensa is classical sign of disease.# Hearing loss: There is a severe hearing...
2
Marginal perforation of tympanic membrane
Multiple perforation of pars tensa
Large central perforation of tympanic membrane
Attic perforation
ENT
Disorders of Middle Ear (Otitis Media)
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single
True about 'Customs' is/are
(AH of the above)
4
Rigid rules and laws of society
No member can escape
Public take active part in its enforcement
All of the above
Social & Preventive Medicine
Social Science, Mental Health & Genetics
cde6dc2d-d9f2-4ff1-a7f7-a9306c47c8ae
multi
Smooth muscle contraction due to release of calcium, occurs because of ?
In Smooth muscles, rise in intracellular leads to binding of 4 Ca++ ions with calmodulin. Calcium-calmodulin complex then activates myosin light chain kinase (MLCK). MLCK phosphorylates the regulatory light chain of myosin; this phosphorylation then leads to interaction of myosin with actin. Calmodulin is structurally ...
4
Increased cAMP
Calcium combining with troponin C
Increased cGMP
Calmodulin-dependant myosin light chain kinase
Physiology
Smooth Muscle
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single
ZOE is not used for permanent cementation because of?
DISADVANTAGES It does not adhere well to enamel and dentin; hence, it causes microleakage and cannot be used for interim and long-term restorations. Due to its low strength and high solubility, it cannot be used for permanent cementation(1st choice will be low strength then low solubility if asked in exams). Its solub...
1
Less strength
High solubility
Poor marginal seal
Poor pulpal protection
Dental
null
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single
True Statement about silicosis -
Ans. is 'b' i.e., Associated with tuberculosis Silicosis 3 Silicosis is a lung disease caused by inhalation of crystalline silicon dioxide (silica). o Currently, it is the most prevalent occupational disease in the world. Silicosis is a slowly progressive disease, usually presenting after decades of exposure as slowly ...
2
Produces pleural plaque
Associated with tuberculosis
Lower lobe infiltration
All
Pathology
null
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multi
Mutations in Marfans syndrome is in:
Fibrillin
2
Collagen
Fibrillin
Elastin
Fibrin
Pathology
null
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single
The commonest type of tracheoesophageal anomaly is -
Tracheoesophageal fistula and esophageal atresia Esophageal atresia is the most common congenital anomaly of the esophagus. More than 90% are associated with tracheoesophageal fistula. The most common variety is the one where upper part of esophagus ends blindly and the lower part is connected to trachea-by a fistula....
2
Esophageal atresia without tracheoesophageal fistula
Esophageal atresia with distal tracheoesophageal fistula
Esophageal atresia with proximal tracheoesophageal fistula
Tracheoesophageal fistula without esophageal atresia
ENT
null
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single
In concussion trauma, damage to ocular structures is caused by:
Ans. All of the above
4
Mechanical tearing of the tissues
Disruption of physiological activity by damage to tissue cells
Vascular damage leading to ischaemia
All of the above
Ophthalmology
null
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multi
Etomidate causes all except-
Ans. is 'a' i.e., Coronary insufficiency o Etomidate is most cardiostable inducing agent. It can cause nausea and vomiting, decreased adrenal steroids and decrease in ICI.
1
Coronary insufficiency
Decreased steroid
Decreases Intracranial tension
Nausea and vomiting
Pharmacology
null
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multi
Cerebral palsy in which upper limb is less affected than lower limb
Ans. is 'a' i.e., Spastic diplegia
1
Spastic diplegia
Spastic paraplegia
Spastic Quadriplegia
Spastic hemiplegia
Pediatrics
null
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single
A 45 yrs old man presents with progressive cervical lymph nodes enlargement, since 3 months; most diagnostic investigation is:
In cervical lymph node enlargement, if no mucosal lesion is detected, an excision biopsy of the largest node should be performed. Ref: Harrison's Internal Medicine, 15th Edition, Page 362 and 18th Edition, Page 467.
3
X-ray soft tissue
FNAC
Lymph node biopsy
None of the above
Surgery
null
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multi
Which of the following is a WRONG pair regarding features of cranial nerves:
Most common nerve involved in basal skull fracture is Facial nerve. Most common nerve involved in raised intracranial tension is Abducent nerve . Most common nerve affected during spinal anesthesia is also Abducent nerve. Most commonly involved in intracranial aneurysm is Oculomotor nerve ansd not optic nerve. An aneur...
4
Most commonly involved in basal skull fracture: Facial nerve
Most commonly involved in raised intracranial tension: Abducent nerve
Most commonly affected in spinal anaesthesia: Abducent nerve
Most commonly involved in intracranial aneurysm: Optic Nerve
Anatomy
Cranial Nerves
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single
A 6 months old baby coming with /o increasing difficulty in breathing of 2 days duration and on examination baby is afebrile & B/L wheeze & CXR shows B/L hyperinflation of the lungs with normal WBC count, the diagnosis is –
Clinical manifestations of bronchiolitis The usual course of the disease is 1-2 days of → Fever, Rhinorrhea, Cough This is followed by - Wheezing   Cyanosis   Tachypnea  Nasal flaring      The breathing pattern is shallow Rales, crepitation and Ronchi  Respiratory distress → retraction of intercostal space & suprast...
1
Bronchiolitis
Asthma
Ch. Bronchitis
Pneumonia
Pediatrics
null
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single
The half life of I133 -
Ans. is 'd' i.e. 8 days
4
4 hours
4 days
6 days
8 days
Pharmacology
null
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single
Which is the principle for management of diabetic foot?
Ans: a. (Control of DM)Ref: Cuschieri, 4th ed. pg. 783The treatment of diabetic foot should be multi disciplinary involving vascular surgeon, diabetologist, and chiropodist. The main pathophysiology of diabetic foot involves a combination of neuropathy, infection and ischaemia. The goal of management should be control ...
1
Control of DM
Topical antibiotics is paramount
Protection of the other limb
Early amputation
Surgery
Wounds, Tissue Repair & Scars
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Not a complication of total parenteral nutrition
.Biochemical COMPLICATIONS OF TOTAL PARENTERAL NUTRITON INCLUDES 1. Electrolyte imbalance: Hyponatraemia, hypokalaemia, hypophosphataemia. 2. Hyperosmolarity. 3. Hyperglycaemia. - common. 4. Dehydration. 5. Altered immunological and reticuloendothelial function. 6. Azotaemia. ref:SRB&;s manual of surgery,ed 3,pg no 89
3
Hyperammonemia
Hypercholesterolemia
Neutrophil dysfunction
Hyperphosphatemia
Surgery
Urology
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single
Which drug resistance differentiates the non fermenters, Psedomonas and burkholderia?
Burkholderia can be differentiated from Pseudomonas by it's resistance to polymyxin, As polymyxin B is used for treating Psedomonas infection
4
Resistance to ampicillin
Resistance to ceftazidime
Resistance to ciprofloxacin
Resistance to polymyxin B
Anatomy
Bacteriology
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single
Fluid best for postmortem investigation?
Ans. b (Vitreous) (Ref. Reddy FMT 23rd/pg. 332).There is a linear relationship between potassium concentration in vitreous and time after death up to 120 hours.Also Know:* The component of vitreous humour that is most useful in determining time since deathPotassium* Mucopolysacchride maximally present in vitreous humou...
2
CSF
Vitreous
Synovial fluid
Serum
Forensic Medicine
Death and Medicolegal Aspects
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single
All are false about tigecycline, except:
Ans. d. Not preferred in UTIRef: Goodman Gilman 12th e/P 1523Tigecycline, doxycycline and minocycline are safe in renal failure.Tigecycline is active against gram negatives with the exception of pseudomonas, providencia, morganella and proteus.Tigecycline has poor bioavailability and hence is given only by parenteral r...
4
Dose reduction in renal failure
90% pseudomonas strains are sensitive
Oral and parenteral bioavailability is same
Not preferred in UTI
Pharmacology
Anti Microbial
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multi
Misoprostol is a:
Natural prostaglandin in the body is PGE2 whereas misoprostol and alprostadil are synthetic PGs which are PGE1 analogues.
1
Prostaglandin E1 analogue
Prostaglandin E2 analogue
Prostaglandin antagonist
Antiprogestin
Pharmacology
null
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single
The mechanism responsible for sustained vascular smooth muscle contraction is
Latch bridge mechanism: - Once smooth muscle has developed full contraction, the amount of continuing excitation can usually be reduced to far less than the initial level even though the muscle maintains its full force of contraction. Fuher the energy consumed to maintain contraction is often miniscule, sometimes as li...
3
Sustained calcium release from SERCA pump
Vascular smooth muscle tone
Latch bridge mechanism
Henneman principle
Physiology
JIPMER 2018
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single
Gastro-colic reflex is related to :
A i.e. Mass persistalsis
1
Mass peristalsis
Segmental movement
Pendular movement
Colonic cases
Physiology
null
1bf538c7-a278-41ab-b577-0db055f9c8d1
single
Middle cardiac vein is accompanied by
The middle cardiac vein commences at the apex of the hea; ascends in the posterior longitudinal sulcus along with posterior interventricular aery, and ends in the coronary sinus.Ref: V.S Volume 1; 2nd edition; Page: 276
3
Anterior interventricular aery
Left circumflex aery
Posterior Interventricular aery
Diagonal aery
Anatomy
Thorax
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single
Killian's dehisence is seen in ?
Ans. is 'c' i.e., Cricopharynx Inferior constrictor muscle has two pas :- (i) Thyropharyngeous with oblique fibres, and (ii) Cricopharyngeous with transverse fibres. Between these two pas of inferior constrictor exists a potential gap called Killan's dehiscence. It is also called the gateway to tear as perforation can ...
3
Oropharynx
Nasopharynx
Cricopharynx
Vocal cords
Anatomy
null
269f6ff3-509c-40d2-b608-0e05d085ae96
single
White piedra is caused by
.
4
Piedraia hoae
Pityrosporum orbiculares
Hoae werneckii
Trichosporon beigelii
Pathology
All India exam
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single
An 86-year-old man has become progressively unable to live independently for the past 10 years, and he now requires assistance with bathing, dressing, toileting, feeding, and transfers in and out of chairs and bed. On physical examination, he has no motor or sensory deficits. He cannot give the current date or state wh...
Alzheimer's disease (AD) can be complicated by cerebral amyloid angiopathy and terminal hemorrhagic stroke. Formation and aggregation of the Ap peptide are now considered central to the pathogenesis of AD. Ap peptide is derived from the abnormal processing of amyloid precursor protein (APP). When APP, a transmembrane p...
1
Aggregation of Ab peptide
Conformational change in the prion protein (PrP)
Dopamine deficiency
Expansion of polyglutamine repeats
Pathology
Central Nervous System
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single
The commonest site for hypertensive intracerebral bleed is:
Ans. is 'a' i.e. Putamen Most common site of hypertensive hemorrhage is-Basal Ganglia (Putamen, thalamus & adjacent deep white matter) Also RememberM.C. intracranial hemorrhage: Intracerebral or intraparenchymal hemorrhage *M.C. cause of intracerebral hemorrhage: Hypertension due to rupture of small penetrating arterie...
1
Putamen.
Cerebellum.
Pons.
Midbrain.
Medicine
Cerebrovascular
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Which amino acid spares the use of methionine -
Ans. is 'a' i.e., Cysteine "Adequate dietary source of cysteine 'spares ' methionine".o Methionine is an essential amino acid.o Methionine is required for synthesis of cysteine (thus cysteine is non-essential amino acid)o Thus, cysteine can spare the requirment of methionine in diet.
1
Cysteine
Glycine
Histidine
Arginine
Biochemistry
Amino Acids Basics
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single
All are factors determining diffusion across membrane except
Ans b (particle size) Ref: Vasudevan 4th ed pg J3, Guyton 48, Ganong 22nd ed pg 4)Diffusion is affected by concentration gradient, temperature, and membrane pore size.The text given in Guyton about molecular size appears confusing, but it is clearly stated in Vasudevan andSreekumari that "permeability does not depend o...
2
Temperature
Particle size
Membrane pore size
Concentration gradient (Repeat, 2008)
Physiology
General
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multi
Which of the following statement is false about the condition depicted in given diagram ?
Radial hemimelia -Radial club hand -Deficiency of radial bone and thumb (40% of hand) - Hand deted to radial side - Associated conditions: 1. Hold Oram syndrome 2. VACTERL Management: -Pollicization (create thumb) -Centralization of ulna
2
Caused by deficiency of Radial bone and thumb
Hand is deted to Ulnar side .
Associated conditions are Holt Oram syndrome and VACTERL .
Preferred management is Pollicization and Centralization of ulna .
Orthopaedics
Pediatric Ohopedics
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multi
Minimum concentration of reduced hemoglobin required for cyanosis is -
null
3
1 gm/dl
3gm/dl
7gm/dl
9gm/dl
Medicine
null
543274dd-a6ae-4a27-85bd-eb50c1da4725
single
Mechanism of action of zileuton:-
Zileuton is a selective and specific inhibitor of 5-lipoxygenase, preventing the formation of both LTB4 and the cysteinyl leukotrienes. Because zafirlukast and montelukast are selective antagonists of the cysteinyl leukotriene- 1 receptor, they block the effects of cysteinyl leukotrienes. All three drugs are approved f...
2
Cyclooxygenase inhibitor
5-lipooxygenase inhibitor
5-phosphodiesterase inhibitor
Prevents mast cell degranulation
Pharmacology
Respiratory System
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single
Menstrual regulation is done upto: September 2010
Ans. C: 49 days of Amenorrhea Menstrual regulation provides best results when a person repos between the 35th-45th day from the last menstrual period (LMP) and the MR is done before the 49th day since the LMP. It has been observed that the procedure gives optimum results in terms of least occurrence of associated risks...
3
35 days of Amenorrhea
42 days of Amenorrhea
49 days of Amenorrhea
56 days of Amenorrhea
Gynaecology & Obstetrics
null
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single
A road traffic accident patient presents with breathlessness. Differentiation between cardiac tamponade and tension pneumothorax is best done by?
Ans. (d) Breath soundsRef. B&L page 354/ 26th Edition* Both Tension pneumothorax and Cardiac tamponade both present with breathlessness, tachypnea and distended neck veins* Tension pneumothorax features - Hyper resonance over the chest and absent breath sounds.* Cardiac tamponade - Classically, the presentation consist...
4
Pulse pressure
Pulse volume
JVP
Breathing sounds
Surgery
Trauma
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single
An orphan population of 7-13 yrs age has been put on lacto vegetarian diet, which study it was?
null
2
Turku study
Hope wood house study
Vipeholm study
Tristan da cunha study
Dental
null
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single
Biopsy of a persistent exophytic area on the vulva of a 60 year old woman demonstrates a squamous epithelial lesion. No koilocytes are seen. The lesions show papillary projections composed of disordered, squamous epithelium with well differentiated cells. The basement membrane at the dermal-epidermal junction is focall...
The disruption of the basement membrane with cell groups extending deep into the dermis indicates that this is invasive squamous cell carcinoma of the vulva, which may arise in vulvar intraepithelial neoplasia, in condyloma, or spontaneously. The latter type (which is likely here) tends to be well differentiated, while...
4
Condyloma acuminatum
Extramammary Paget's disease
Vulvar intraepithelial neoplasia
Vulvar squamous cell carcinoma
Pathology
null
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multi
"Phantom calyx/Amputated calyx" on IVU is feature of?
Ans. A. TuberculosisEarly renal tb: IVUAdvanced renal tb: CTRadiologic findings in renal tb include:a. Urographic demonstration (ivu) of diminished excretion of the contrast medium, focally or generally.b. Poorly defined one or more calyces.c. Cavitation communicating with the pc system, demonstrable by urography or re...
1
Tuberculosis
Hydronephrosis
Bilharziasis
UPJ obstruction
Radiology
Miscellaneous
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single
Following are the features of raised intracranial tension except -
There is Bradycardia.
4
Altered sensorium
Papilloedema
Convulsions
Tachycardia
Surgery
null
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multi
In primary open-angle glaucoma pilocarpine eye drops lowers the intraocular pressure by its direct action on the:
Ans. Longitudinal fibres of the ciliary muscle
3
Trabecular meshwork
Ciliary epithelium
Longitudinal fibres of the ciliary muscle
All of the above
Ophthalmology
null
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multi
Formaldehyde gas sterilization is employed for?
Formaldehyde gas is used for sterilising instruments and heat sensitive catheters and for fumigating wards and sick rooms and laboratories REF:Ananthanarayan and Panicker's Textbook ofMicrobiology 8thEdition pg no:36
4
Sterilizing hea lung machines
Glass materials
Paper and cloth
Fumigation of operation theater
Microbiology
general microbiology
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single
All of the following statements about Penicillin resistance are true, Except -
Ans. is b i.e., Alteration in target PBPs is an impoant resistance mechanism in gram negative bacteria PENICILLIN RESISTANCE o Mechanism of resistance are ? Penetration into the cell o Gram negative bacteria have an outer membrane just outside the cell wall. o Outer membrane is not present in gram positive bacteria, so...
2
beta-Lactamase production is the most common mechanism of resistance
Alteration in target PBPs is an impoant resistance mechanism in gram negative bacteria
Alteration in permeability/penetration of antibiotic causes resistance only in gram negative bacteria
beta-Lactamase production causes resistance in both gram positive and gram negative bacteria
Pharmacology
null
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multi
Phlyctenular conjunctivitis false is-
Tuberculous proteins were considered, previously, as the most common cause. Staphylococcus proteins are now thought to account for most of the cases. Age. Peak age group is 3-15 years. Phlyctenular keratoconjunctivitis is believed to be a delayed hypersensitivity (Type IV-cell mediated) response to endogenous microbial...
1
The most common cause is tuberculosis
The lesions are typically found near the limbus
Predominantly affects children
Is a type IV hypersensitivity reaction
Ophthalmology
Conjunctiva
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multi
A patient of glaucoma with bronchial asthma presents to the emergency with status asthamaticus, causative agent might have been)
Ans. is 'b' i.e. Timolol eye drops Timolol maleate is the most widely used drug for open angle glaucoma.It is non-selective B blocker (Blocks both B1 and B2B2 is responsible for bronchodilation, therefore blocking B2 would aggravate asthma.Instead of Timolol, Betaxolol can be used because it is a selective B1 blocker a...
2
Pilocarpine eye drop
Timolol eye drop
Betaxolol eye drop
Levobunolol eye drop
Ophthalmology
Primary Open-Angle Glaucoma and Related Conditions
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