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Locus heterogeneity is feature of
Ans. c (Muscular dystrophies) (Ref. H - 18th/Ch. 63; 16th/pg. 360).Many disorders exhibit the feature of locus heterogeneityf which refers to the fact that mutations in different genes can cause phenotypicaily similar disorders. For example, osteogenesis imperfecta, long QT syndrome, muscular dystrophy, homocystinuria,...
3
Familial adenomatous polyposis
Osteopetrosis
Muscular dystrophies
All of the above
Medicine
Genetics
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multi
Registration of birth & death with a 6 monthly survey is done in -
Ans. is 'd' i.e., Sample registration system Sample registration systemo Sample registration system (SRS), initiated in mid 1960s provides reliable estimates of birth (fertility) and death (mortality) rates at state and national Levels.o It is a dual record system .consisting of continuous enumeration of birth and deat...
4
National sample survey
Vital statistical system
Census
Sample registration system
Social & Preventive Medicine
Statistical Tests
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single
A 30 year old male with a history of alcohol abuse for 15 years is brought to the hospital emergency with complaints of fearfulness, misrecognition, talking to self, aggressive behavior, tremulousness and seeing snakes and reptiles that are not visible to others around him. There is a history of drinking alcohol two da...
This patient has:- H/O alcohol abuse Abstinence from alcohol drinking for two days Visual hallucinations (seeing snake & reptiles) Disorientation (misrecognition, talking to self) Anxiety (fearfulness and tremulousness) All suggest the diagnosis of delirium tremens.
1
Delirium tremens
Alcoholic hallucinosis
Schizophrenia
Seizure disorder
Psychiatry
null
a07d6f6b-7b3b-4e01-bcd7-7ce6da4ef8be
multi
OR is not required in which fracture:?
B i.e. Outer 1/3rd of radius Treatment Plan of Fracture Head of Radius Undisplaced split Single large displaced Small, displaced non - Comminuted fracture 1 aicular (inner 2/3) aicular (outer 1/3.1) - Fracture dislocation * Immobilization in above elbow fragment fragment POP with cuff & collar sling. 1 1 Excision of ra...
2
Patella
Outer 1/3 of radius
Condyle of humerus
Olecranon displaced
Surgery
null
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single
A patient comes in eye OPD presents with diplopia,headache and blurring of vision. On examination while attempting right gaze, right eye abducts but left eye fails to adduct. Patient's right gaze is normal,convergence is also normal. The lesion is most probably in the following:-
Right cerebral coex is the command centre for right gaze origination. These signals runs through right paramedian reticular formation (PPRF) From PPRF signals reach VI cranial nerve nucleus of same side (Right here) which in turn supplies the lateral rectus causing abduction. Signals from Right PPRF also goes to III cr...
1
Left MLF
Left PPRF
Right MLF
Right PPRF
Medicine
Miscellaneous QBank
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Cervical stroma consists of?
Ans. is 'a' i.e., Racemose glands The glands which dip into the stroma are of complex racemose type and are lined by secretory columnar epithelium.There is no stroma in the cervix unlike the corpus and the lining epithelium rests on a thin basement membrane.The change in the epithelium and the glands during menstrual c...
1
Racemose glands
Tubular glands
Alveolar glands
Coiled tubular glands
Gynaecology & Obstetrics
null
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single
Maximum scattering in X Ray plate occurs in
C i.e. H+ Major difference between x-rays & light are wave length (A) & energyQ Electromagnetic radiation or photon waves are non paiculate (0-mass), non charged (0-charge) waves, that do not require a medium to travel (i.e. can travel in vaccum) and transfer energy from one location to another at the speed of light (c...
3
Carbon
Mercury
H+
Ca++
Radiology
null
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single
The oxidation of Galactose with strong oxidizing agent produces:
Option a : Oxidation of galactose with strong oxidizing agent produces mucic Acid In the presence of strong oxidizing agent, both first and last carbon of sugar is oxidized to produce Saccharic Acid. If Aldehyde group (C1) is oxidized, then Aldonic Acid is produced. If last carbon (C6) is oxidized, then Uronic Acid is ...
1
Mucic Acid
Gluconic Acid
Galacturonic acid
Saccharic Acid
Biochemistry
Classification of carbohydrate
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Site of diabetic foot ulcera) Medial Malleolusb) Lateral malleolusc) Heeld) Head of metatarsale) Head of toes
"Diabetic ulcers commonly result from decreased protective sensation. Diabetic ulcers are usually found on the plantar surface of the foot over the metatarsal heads or heel." - Sabiston.
1
cd
bc
bd
ac
Surgery
null
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multi
About rectal route true is ?
Ans. is 'a' i.e., Used for irritant and unpleasant drugs Rectal route of administration It is a route of systemic drug delivery. Irritant or unpleasant drugs can be put into the rectum as suppositories or retention enemas. Can be used in a patient with recurrent vomiting and in unconscious patient. Absorption of drug i...
1
Used for irritant and unpleasant drugs
Cannot be used in unconscious patient
There is predictable absorption of drug
Diazepam cannot be given rectal route of administration
Pharmacology
null
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Following urethral rupture, immediate procedure to be done is: September 2008, March 2009
Ans. B: Suprapubic cystostomy Patient should be discouraged from passing urine if urethral rupture is suspected. Drainage of full bladders with paial tears can be managed with a suprapubic catheter. Suprapubic cystostomy has the benefit of avoiding urethral manipulation, which can produce fuher urethral trauma and allo...
2
Urinary catheterization
Suprapubic cystostomy
Referral to a urologist
Observation
Surgery
null
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All are symptoms of Plumbism, except
Chronic lead poisoning is manifested by facial pallor, anaemia, basophilic stippling of red cells, blue line in the gum (Buonian line), retinal stippling and in the later phase by colic, constipation, palsy, encephalopathy, disturbance of genito-urinary and cardiovascular system . Aldrich-Mees lines are seen in arsenic...
3
Punctuate basophilia
Encephalopathy
Aldrich-Mees lines
Eosinophilia
Forensic Medicine
Poisoning
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multi
Charas is -
Charas or Hashish is resinous exudates from the leaves and stems of plant cannabis indica or cannabis sativa.
4
Leaves of Cannabis Indica
Flowers of Cannabis Indica
Stem of Cannabis Indica
Resin exudate Cannabis Indica
Forensic Medicine
null
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Investigation of choice to diagnose congenital hip dislocation in neonates?
Ans BIn neonates the femoral head is cartilaginous and not ossified hence it cannot be identified on radiographs but well demonstrated on USG. Also the Graf's classification using Alpha and Beta angles are very definitive in assessment and can be readily calculated on USG.
2
Plain radiographs
US
CT
MRI
Radiology
Skeletal System
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Duration of action of flumazenil is
Duration of action of flumazenil is 30-60min. So the best answer seems to be 30min The onset of action is about 1 to 2 minutes; 80% response is seen within the first 3 minutes. Peak effect is 6 to 10 minutes after administration.Duration range is from 19 minutes to 50 minutes as it depends on the dose was given and ben...
4
5minute
10minute
20minute
30minute
Pharmacology
Central Nervous system
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Anaesthetic that has a smooth induction is-
Ans. is 'b' i.e., Thiopental o This question is straight forward as amongst the given options only thiopental is used as inducing agent. o Iv. inducing agents are used for induction because of rapid and smooth induction and drugs used for this purpose are: i) Thiopentone iii) Propofol ii) Methohexitone sod iv) Etomidat...
2
Diethyl ether
Thiopental
N2O
Halothane
Pharmacology
null
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Genetic deficiency of complement factor causes:
Ans: d (All of the above) Ref: Ananthanaraya 7th ed, p. 115Deficiency of complement components are associated with a variety of syndromesDeficiencySyndromeCl inhibitorHereditary angoneurotic edema (main mediator of edema is C2 kinin released)C1C2C4SLE & collagen vascular disordersC3 & C3b inactivatorRecurrent pyogenic ...
4
Hereditary angioneurotic edema
SLE- an autoimmune disease
Pyogenic bacterial infections
All of the above
Microbiology
Immunology
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Agnus Hunt traction used in
null
1
Flexion deformity of hip
Fracture femur shaft
Fracture neck of femur
Intertrochanteric fracture
Orthopaedics
null
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single
At a flow rate of 3L/min, inspiratory (FUO2) concentration of 30–60% can be achieved by using a –
Nasopharyngeal catheter deliver 32% of O2 (FiO2 → 0.32) at flow-rate 3 litre / minute.
1
Nasopharyngeal catheter
Simple face mask
Venturi mask
Head box
Anaesthesia
null
d604c033-7538-4752-83d4-8933bed232d8
single
No change of genetic material occurs in which of the following cytogenetic abnormalities?
Inversion Rearrangement that involves two breaks within a single chromosome with reincorporation of the inveed, intervening segment. Not associated with change in genetic material.
4
Deletion
Inseion
Translocation
Inversion
Pathology
Genetics
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single
All are true in paralytic squint except
Clinical features of paralytic squint are : Symptoms : Diplopia Confusion Nausea and veigo Ocular detion Signs : Primary detion Secondary detion- It is greater than Primary detion due to the fact that the strong impulse of innervation required to enable the eye with paralysed muscle to fix is also transmitted to the yo...
4
Diplopia
False projection
Compensatory head posture
Primary detion is equal to secondary detion
Ophthalmology
Ocular motility and squint
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Which of the following is true about Eruption of teeth __________
Eruption times vary from child to child.The first teeth begin to break through the gums at about 6 months of age. Usually, the first two teeth to eruptare the two bottom central incisors (the two bottom front teeth). Next, the top four front teeth emerge. Reference: GHAI Essential pediatrics, 8th edition
2
Premolar appear in Primary dentition
Incisors appear first in secondary dentition
3rd molar is last to develop
Hypothyroidism delays dentition
Pediatrics
Growth and development
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Antenatal screening test done in the maternal serum is _______
Antenatal screening test done in the maternal serum is cell-free fetal DNA testing, which is a non-invasive prenatal screening. This test is done using the freely circulating fetal cells in the maternal serum. It is useful for karyotyping and for detecting single gene disorders. Invasive procedures for prenatal diagnos...
2
Percutaneous unbilical blood sampling
Cell-free fetal DNA testing
Chorionic villus sampling
Amniocentesis
Pediatrics
New born infants
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ECT causes -
Most common complication of ECT is amnesia. Both retrograde and antegrade amnesia occurs. Retrograde amnesia is more common than antegrade.
3
Antegrade amnesia
Retrograde amnesia
Both
None
Psychiatry
null
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True about infiltrating lobular breast carcinoma:-
LCIS originates from the terminal duct lobular units and develops only in the female breastQ. LCIS is mostly multicentric & bilateralQ Increased risk of invasive carcinoma is in the both breastsQ. Calcifications associated with LCIS typically occur in adjacent tissues (neighborhood calcification)Q Histologic hallmark o...
1
Indian file pattern
Adjacent areas are not calcified .
Mostly unilateral
Devolps both in male and female breast .
Surgery
Breast
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multi
"Hitler intended to improve German race by killing the weak and defective"- this is an example of:
Negative eugenics has little application in civilized world. People suffering from serious hereditary diseases may be sterilized or otherwise debarred from producing children. Ref: Park 21st edition page: 767.
2
Positive eugenics
Negative eugenics
Euthenics
Gene therapy
Social & Preventive Medicine
null
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single
Oil and Grease are sterilized by:
Ans: A (Hot air oven) Ref: A nanthana ray an, Paniker CJ. Textbook of microbiology. 8th Edition. London: John Wiley & Sons: 2009. Pg. 30-38.Explanation: (See table below) Disinfectant/ SterilisationActive againstUseEthyl alcoholBactericidal but not sporicidalSkin antisepticsMethyl alcoholActive against bacterial and fu...
1
Hot air oven
Autoclaving
Filtration
Irradiation
Microbiology
General
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single
50 people are suffering from cholera in a population of 5000. Out of 50, suffering from cholera, 10 died. But the total deaths are 50. What is the death rate
One DALY is equal to one year of healthy life lost.  It is a disability indicator and Japanese life expectancy is used as a standard. Disability - adjusted life year (DALY1 o DALY is a measure of :- i. The burden of disease in a defined populaon ii. The ef ectiveness of inten'entions  It expresses years lost to prematu...
1
10 per 1000
10 per 1000
5 per 1000
20 per 100
Social & Preventive Medicine
null
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Stage of 16 cells is
A morula is distinct from a blastocyst in that a morula (3-4 days post feilization) is a 16-cell mass in a spherical shape whereas a blastocyst (4-5 days post feilization) has a cavity inside the zona pellucida along with an inner cell mass
2
Embryo
Morula
Zygote
Blastocyst
Anatomy
General anatomy
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single
Rossmann fold associated NADH domain is found in which enzyme?
Lactate dehydrogenase is comprised of two domains, an N-terminal NAD+ -binding domain and a C-terminal binding domain for the second substrate, pyruvate. Lactate dehydrogenase is one of the family of oxidoreductases that share a common N-terminal NAD(P)+ -binding domain known as the Rossmann fold. By fusing a segment o...
1
Lactate dehydrogenase
Pyruvate dehydrogenase
Malate dehydrogenase
Isocitrate dehydrogenase
Biochemistry
null
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single
Seoli cells in the testis have receptors for
Seoli cells secrete inhibin. They have receptors for FSH. LH acts on Leydig cells, which secrete testosterone.
1
FSH
LH
Inhibin
All of the above
Physiology
Male Reproductive System
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Hypersensitivity vasculitis is seen most commonly in
HYPERSENSITIVITY VASCULITISIn hypersensitivity vasculitis, postcapillary venules are the most commonly involved vessels, capillaries and aerioles are involved less frequently.It is primarily a disease of small vessels.It is characterized by leukocytosis, a term that refers to the nuclear debris remaining from the neutr...
1
Postcapillary venules
Aerioles
Veins
Capillaries
Microbiology
All India exam
47518a17-43b4-47bc-a2bb-2f224457060e
single
The following structure represents which impression material?
null
2
Polyether
Polysulfide
Condensation silicone
Addition silicone
Dental
null
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single
False positive veneral desease research laboratories (VDRL) test have been associated with all thefollowing except -
null
4
Narcotic addiction
Atypical pneumonias
Old age
Diabetes mellitus
Medicine
null
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multi
Increased IgA deposits are seen in -
Henoch schonlein purpura This syndrome consists of Pruritic skin lesions characteristically involving the extensor surfaces of arms and legs as well as buttocks. Abdominal manifestations → Pain, vomiting, bleeding Nonnzigratory arthralgia Renal abnormalities The disease most commonly affects children between 3 to...
1
Henoch Schonlein Purpura
Minimal Change Glomerulonephritis
Chronic Pyelonephritis
Haemolytic Uraemic Syndrome
Pathology
null
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Which of the following is not true about acute retropharyngeal absess:
M/C cause acute retropharyngeal abscess in children is suppuration of retro pharyngeal lymphnodes secondary to infection of adenoids, nasopharynx and nasal cavity. The M/C cause of acute retropharyngeal abscess in adutls is penetrating injury of posterior pharyngeal wall or cerivcal esophagus.
4
Dysphagia
Swelling on posterolateral wall
Toicollis
Caries of cervical spine is usually a common cause
ENT
null
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multi
Single most common finding in Aphasic Patients
*A deficit of naming (anomia) is the single most common finding in aphasic patients. The persistent inability to find the correct word is known as anomia (literally, 'without names'). Anomia is actually a symptom of all forms of aphasia, but patients whose primary language problem is word retrieval are diagnosed as hav...
1
Anomia
Apraxia
Alexia
Agraphia
Medicine
C.N.S
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Burning test syndrome is seen due to deficiency of
null
2
Vitamin B3
Vitamin B5
Vitamin B6
Vitamin B7
Social & Preventive Medicine
null
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single
Which of the following insulin should not be mixed with other insulins?
Insulin preparations: Sho acting insulin - Aspa Glulisine Lispro Regular Intermediate acting -> Lente insulin Long acting insulin Detemir Degludec NPH Ultra long acting insulin: Glargine Inhaled insulin - Afrezza All insulin preparation are available at neutral pH. Insulin glargine has acidic pH<4, so insulin glargine ...
1
Glargine
Aspa
Lispro
Regular
Pharmacology
Pancreas
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single
A 20-year-old female presents with excess facial hair and oligomenorrhea, increased levels of free testosterone, and normal ovaries on USG. Most likely diagnosis is:
Ans. A. PCODa. PCOS/PCOD is a disorder of chronically abnormal ovarian function (oligo/anovulation) and hyperandrogenism frequently a/w hyperinsulinemia and insulin resistance, resulting in menstrual irregularity, infertility, and hirsutism.b. Rotterdam 2003 criteria for diagnosis of PCOS/PCOD:c. At least 2 of 3 should...
1
PCOD
Adrenal hyperplasia
Idiopathic hirsutism
Testosterone-secreting tumor
Gynaecology & Obstetrics
Miscellaneous (Obs)
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All are true regarding Seminoma EXCEPT
C. i.e. (Radio resistant) (1312 - 13. S. Das 5th) (1385-B & L 25th)* Testicular seminoma is remarkably radiosensitive tumour and vigorous attempt should be made to irradicate the tumour even in patients with advanced diseaseSEMINOMA - is the most common form of testicular tumour in the adult (Between 35 and 45 years). ...
3
Common in age between 35 and 45 years
Metastasis to lymphatics
Radio resistant
Not seen before puberty
Surgery
Testis & Scrotum
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Longest muscle in the body
REF BD CHAURASIAS HUMAN ANATOMY SIXTH EDITION VOLUME 2 PAGE 53 Saorius is long narrow and ribbon like it run downwards and medially across the front of thigh .it is the longest muscle in the body. It orgin :anterior superior iliac spine Ipper half of notch below spine Inseion: medial surface of shaft of tibia upper pa
3
Biceps
Triceps
Saorius
Quadriceps
Anatomy
General anatomy
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Specific reason to disallow the sample for culture-
null
3
Sample brought within 2 hr of collection
Sample brought in sterile plastic container
Sample brought in formalin
Sample obtained after cleaning the collection site
Microbiology
null
13eff325-17a4-4a87-8590-af19d0faa4e1
multi
Giant papillary conjunctivitis can be secondary to:
Ans. (b) Contact lensGIANT PAPILLARY CONJUNCTIVITIS* It is the inflammation of conjunctiva with formation of very large sized papillae.* Cause: It is a localized allergic response to a physically rough or deposited surface (contact lens, prosthesis, left out nylon sutures).* Symptoms: Itching, stringy discharge and red...
2
Trachoma
Contact lens
Phlyctenular conjunctivitis
Vernal kerato conjunctivitis
Ophthalmology
Inflammations of Conjunctiva - Allergic and Granulomatous
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All of the following features are seen in asbestosis except
Asbestosis is a diffuse interstitial fibrosing disease of the lung that is directly related to the intensity and duration of exposure.The disease resembles other forms of diffuse interstitial fibrosis. Past exposure to asbestos is specifically indicated by pleural plaques on chest radiographs, which are characterized b...
3
Diffuse pulmonary interstitial fibrosis
Fibrous pleural thickening
Emphysema
Calcific pleural plaques
Anatomy
Respiratory system
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multi
All of the following clinical features are seen in a patient with cystic fibrosis, EXCEPT:-
Cystic fibrosis is associated with hypochloremic metabolic alkalosis not metabolic acidosis. It can also cause respiratory acidosis. Impoant causes of chronic respiratory acidosis in children are chronic lung disease, cystic fibrosis, extensive bronchiectasis and neuromuscular defects. Children with cystic fibrosis dev...
1
Metabolic acidosis
Steatorrhoea
Hypochloremia
Recurrent pneumonias
Medicine
null
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multi
A 2-day-old male infant is hospitalized in the intensive care unit with acute respiratory distress. Radiographic examination reveals that the patient has anuria, oligohydramnios, and hypoplastic lungs. Facial characteristics are consistent with Potter syndrome. Which of the following is the most likely explanation for ...
Potter sequence, or Potter syndrome, is a rare autosomal recessive trait and is associated with renal agenesis or hypoplasia. Altered facial characteristics include flattened nasal bridge, mandibular micrognathia, malformed low-set ears, etc. Absence or lack of proper development of the kidneys causes oligohydramnios, ...
3
Multicystic dysplastic kidney
Polycystic kidney
Renal agenesis
Wilms tumor
Anatomy
Abdomen & Pelvis
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The most common indication for liver transplantation in end stage liver disease is
.
3
Wilson's disease
Chronic hepatitis B
Chronic hepatitis C
Alcoholic liver injury
Pathology
All India exam
e6393a5b-57e0-4c05-b87c-fdcfcd959256
single
Which of the following is not a phospholipid ?
Ans. is 'd' i.e., Ganglioside Phospholipids are : Glycerophospholipids (glycerol containing) :- Phosphatidylcholine (lecithin), phosphatidylethanolamine (cephaline), phosphatidylserine, phosphatidylinositol, plasmalogens, lysophospholipids, cardiolipin. Sphingophospholipids (sphingosine containing) :- Sphingomyeline
4
Lecithine
Plasmalogen
Cardiolipin
Ganglioside
Biochemistry
null
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A 17 years male presented with swelling in the cheek with recurrent epistaxis. Most likely diagnosis is
A. i.e. (Angiofibroma) (230 - Dhingra 4th) (296 - maqbool 11th)NASOPHARYNGEAL ANGIOFIBROMA* Benign but locally invasive lesion of the nasophagrynx* Exclusively in males 10 and 25 years of age* Lesions arise from the ventral periosteum of the skull as a result of hormonal (imbalance or persistence of embryonic tissue* G...
1
Angiofibroma
Carcinoma nasopharynx
Rhabdomyosarcoma
Ethmyoid polyp
ENT
Nose and PNS
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Second intermediate host of Dichyllobothrium latum is -
Ans. is 'd' i.e., Fresh water fish
4
Cycolps
Man
Snail
Fresh water fish
Microbiology
null
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multi
Which of the following is true regarding mallet finger?
Ans. is 'b' i.e., Rupture of extensor tendon * Mallet finger Has been explained in previous sessions
2
Also known as Badminton finger
Rupture of extensor tendon
Contraction deformity of flexor tendon
Treatment is Open reduction and internal fixation
Orthopaedics
Hand Injuries
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multi
In the shown lateral view, the GIT structure marked with arrow head is?
Normal Lateral Chest Xrays: Normal Findings: - Sternum - Retrosternal space and retrocardiac space should be : clear spaces or lucent areas - Obliteration of Retrosternal space: Right Ventricular Hyperophy - Tracheal Lucency - Lucency of veebra should increase- more black- as we go from top to bottom . - Right dome of ...
3
Esophagus
Pulmonary aery
Trachea
Left atrium
Radiology
FMGE 2019
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single
All are features of Vitamin D Its intoxication, except –
There is polyuria (not oliguria) Hypervitaminosis   The sign and symptoms of vitamin D intoxications are secondry to hypercalcemia which is caused by - Excessive bone resorption (major cause) Vit D causes bone resorption. Increased calcium absorption Manifestations are - GIT         --> Nausea, vomiting, anorexi...
4
Nausea and vomiting
Muscular weakness
Anorexia
Oliguria
Pediatrics
null
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multi
All cranial nerves are confined to the head and neck with exception of
null
1
One
Two
More than two
None of the above
Anatomy
null
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multi
Which of the following is true about alpha 1 antitrypsin?
Alpha 1 antitrypsin : anti elastase protein coded by gene PiMM gene. Any mutation in this gene lead to abnormal formation of alpha 1 antitrypsin protein which leads to Storage of this abnormal enzyme inside hepatocyte instead of it's secretion resulting in manifestation of micronodular cirrhosis of liver and Pan acinar...
1
Inhibits elastase
Inhibits trypsinogen activation in pancreas
Inhibits trypsin activating protease
Inhibits chymotrypsin
Pathology
NEET 2019
8d836ef9-008f-4d08-854a-c283d5db9be0
multi
Which disorder involves a loss of pain sensation on one side of the body coupled with the loss of proprioception, precise tactile localization, and vibratory sensations on the contralateral side of the body?
The Brown-Sequard syndrome is characterized by the loss of pain sensation on one side of the body coupled with a loss of discriminative sensations, such as proprioception, vibratory sensation, stereognosis & motor loss on the opposite side of the body.
4
Herpes zoster
Thalamic pain syndrome
Lateral medullary syndrome
Brown-Sequard syndrome
Physiology
Sensory System
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single
Conscious proprioception is carried by
Sensations carried by posterior column -        Proprioception, Vibration, kinesthesia, fine touch. Sensations carried by anterolateral column -        Temperature, pain (lateral) and crude touch (anterior)
1
Dorsal column fibres
Anterior spinothalamic tract
Lateral spinothalamic tract
Vestibular tract
Physiology
null
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single
Superimposition technique is used in -
Superimposition technique determines whether the skull is that of a person in a photograph or not.
1
Skull
Pelvis
Femur
Ribs
Forensic Medicine
null
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single
For the pathologic sign "Renal stones" select the mediastinal tumor with which it is most likely to be associated (SELECT 1 TUMOR)
Neuroblastoma, a highly malignant tumor of children, occurs along the distribution of the sympathetic nervous system. It is derived from ganglion cell precursors and thus usually causes an increased excretion of catecholamines and their metabolites. Because of its propensity to metastasize to bone and its histological ...
4
Thymoma
Hodgkin's disease
Neuroblastoma
Parathyroid adenoma
Surgery
Heart & Pericardium
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single
Structure which passes through both greater and lesser sciatic foramen
GREATER SCIATIC FORAMEN:- Gateway of gluteal region.1. pyriformis: key muscle of the region. 2. structures passing above pyriformis.A. Superior gluteal nerve B. Superior gluteal vessels. 3. Structures passing below the pyriformis:-Inferior gluteal nerve and vessels.Sciatic nerve Posterior cutaneous nerve of thighNerve ...
3
Nerve to quadratus femoris
Superior gluteal nerve
Nerve to obturator internus
Piriformis muscle
Anatomy
Lower limb
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multi
Enzyme deficient in Galactose, most commonly
Galactose is a substrate for aldose reductase, forming galactitol, which accumulates in the lens of the eye, causing cataract. The condition is more severe if it is the result of a defect in the uridyl transferase since galactose-1-phosphate accumulates and depletes the liver of inorganic phosphateUltimately, liver fai...
3
Galactokinase
Epimerase
Uridyl transferase
None
Biochemistry
Metabolism of carbohydrate
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multi
In second degree burns, re-epithelialisation occurs around:
null
3
1 week
3 week
2 week
4 week
Surgery
null
78e0937b-429b-4424-bf97-e0382d5ec947
single
Child pugh criteria is used for prognosis of which disease
The Child-Turcotte-Pugh score is a scoring system to measure the severity of chronic liver disease inclusive of cirrhosis.It employs the following: serum bilirubin, albumin, presence of ascitis, mental status ( hepatic encephalopathy ), nutrition and prothrombin time seconds prolonged(Pugh's modification ) Reference : ...
1
Terminal liver disease
COPD
CRF
DCM
Surgery
Urology
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single
In compartment syndrome earliest finding is
Ans: a (Pain on passive..) Ref Rocksvood& Greens 6th edPain is considered to be the first symptom of acute compartment syndrome. The pain experienced by the patient is by nature ischemic and usually severe and out of proportion to the clinical situation.Symptoms and signs of compartment syndromeThere are classically 5 ...
1
Pain on passive movement
Parasthesia
Absence of pulse
Pallor
Orthopaedics
Complications In Orthopedics
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multi
Equatorial diameter of the lens is -
Circumferance of the lens is known as equator. its diameter varies from 8.8mm-9.2mm and the anteroposterior diameter varies with accommodation. REF IMG
3
7 mm
8 mm
9 mm
10 mm
Ophthalmology
Lens
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single
Which of the following drugs is an inducer of microsomal enzymes?
Enzyme Inducers G Griseofulvin P Phenytoin R Rifampicin S Smoking Cell Carbamazepine Phone Phenobarbitone Rifampicin induces the following cytochrome enzymes: CYP3A4 CYP1A2 CYP2C9 CYP2C19
4
Erythromycin
Isoniazid
Ketoconazole
Rifampicin
Pharmacology
Pharmacokinetics
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single
Vocal cord palsy in thyroid surgery is due to injury to-
null
2
Superficial laryngeal nerve
Recurrent laryngeal nerve
Ansa cervicalis
Vagus nerve
Surgery
null
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single
Which of the following is NOT TRUE about intermittent claudication?
Relieve of symptoms is not dependant upon sitting or other positional changes. Intermittent claudication: It refers to the pain or fatigue in muscles of the lower limb caused by walking and relieved by rest. Claudication is derived from the latin word for "liping, lame", strictly speaking, the term should be used only ...
2
Most common in calf muscle
Pain is positional
Atherosclerosis is impoant predisposing factor
Relieved by rest
Surgery
null
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multi
A 40-year-old woman presents with progressive palmoplantar pigmentation. X-ray spine shows calcification of IV disc. On adding benedicts reagent to urine, it gives greenish brown precipitate and blue-black supernatant fluid. What is the diagnosis?
Ans. B. AlkaptonuriaAlkaptonuriaAutosomal Recessive disorder is due to a deficiency of Homogentisic Acid Oxidase1st inborn error detectedBelongs to Garrod's Tetrad Biochemical DefectHomogentisate Oxidase deficiency leads to accumulation of Homogentisic Acid (Homogentisate) which polymerises to form Alkaptone bodies.Cli...
2
Phenyl ketonuria
Alkaptonuria
Tyrosinemia type 2
Argininosuccinic aciduria
Biochemistry
Proteins and Amino Acids
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single
The most common translocation seen in patients with Multiple Myeloma is
Answer is A (t(11;14)) The most common translocation seen in patients with Multiple Myeloma is 01;14). `The most common translocation seen in patients with Multiple Myeloma is t(11;14)(q13;q32) involving the BCL1 locus on chromosome 11g13 and the immunoglobulin heavy (IgH) chain locus on chromosome 14q13 which leads to...
1
t(11;14)
t(4;14)
t(14;16)
t(14;20)
Medicine
null
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single
A 3-year-old child's mother notes that a large port wine stain on the left side of the child's face has not diminished in size since birth. This irregular, slightly raised, red-blue area is not painful, but is very disfiguring. Histologically, this lesion is most likely composed of a proliferation of which of the follo...
The most common tumor of infancy is a hemangioma, and these benign neoplasms form a large percentage of childhood tumors as well. Although benign, they can be large and disfiguring. Fibromatoses are fibromatous proliferations of soft tissues that form solid masses. Lymphangioma is another common benign childhood tumor ...
1
Capillaries
Fibroblasts
Lymphatics
Lymphoblasts
Pathology
Disease of Infancy & Childhood
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multi
Most common site of ectopic pancreatic tissue
Accessory pancreatic tissue found in stomach duodenum or mechel's diverticulam.
1
Stomach
Jejunam
Appendix
Hilum of spleen
Anatomy
null
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single
Treatment in 6 month old child with acute watery diarrhoea without signs of dehydration is –a) Mothers milk and household fluidsb) ORS and antibioticsc) Mothers milk and antibioticsd) Mothers milk and ORS
Treatment plan to prevent dehydration - Plan A The mother should be educated to use increased amount of culturally appropriate home available fluids. In addition, they should be given ORS packets for use at home. Breast feeding should not be discontinued.
3
b
c
ad
ab
Pediatrics
null
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single
Blink reflex is used for
Ans. a. Mid pontine lesions The Blink Reflex Test (B) is a neurophysiological examination used for evaluation of brainstem reflex circuits.: In veebrate anatomy the brainstem (or brain stem) is the posterior pa of the brain, adjoining and structurally continuous with the spinal cord. It is usually described as includin...
1
Mid pontine lesions
Neuromuscular transmission
Axonal neuropathy
Motor neuron disease
Medicine
null
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single
True statement regarding Pulmonary ventilation is
A i.e. PaO2 is maximum at apexVentilation perfusion ratio is maximum at the Apex of lungQ and minimum at base.In an upright positionVentilation per unit lung volume is greatest at basePerfusion per unit lung volume is greatest at base- a 2 is maximum at apex.High V- p ratio at the apex accounts for predilection of the ...
1
PaO2 is maximum at the apex.
V/Q is maximum at the base.
Ventilation per unit lung volume is maximum at the apex
Blood circulation is minimum at the base
Physiology
null
3778a9a9-92f0-40aa-a96e-7a9f4b0239e0
multi
A 60-year-old woman presents with generalized edema, skin ulceration and hypeension. Urine examination shows subnephrotic proteinuria
Answer is B > C (Essential mixed cryoglobulinemia): The presence of skin ulceration on clinical examination in a female patient around the 6th decade ors a diagnosis of Essential Mixed Cryoglobulinemia over MPGN. Neveheless if Essential Mixed Cryoglobulinemia were not amongst the options MPGN would be the single best a...
2
Post-streptococcal Glomerulonephritis
Essential Mixed Cryoglobulinemia
Membranoproliferative Glomerulonephritis (MPGN)
Focal SegmentalGlomerulosclerosis (FSGS)
Medicine
null
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single
A 45 year old man who is a known hypeensive complains of fever, migraine, loss of appetite, myalgia and presented with ulcerations on the calf and near the malleoli. On examination, splinter haemorrhages and palpable purpura were noted. On CT angiography, aneurysm and stenosis of medium sized vessels were observed. The...
The most likely diagnosis is polyaeritis nodosa which is an example of Type III hypersensitivity reaction. In type III hypersensitivity, immune complexes may deposit in tissues or blood vessels, and elicit an acute inflammatory reaction by activating the complement system. The inflammatory reaction causes tissue injury...
3
Type 1 hypersensitivity
Type 2 hypersensitivity
Type 3 hypersensitivity
Type 4 hypersensitivity
Microbiology
Immunology
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multi
Unlike other GI secretions, salivary secretion is controlled almost exclusively by the nervous system and is significantly inhibited by:
Ans. A. AtropineSalivary secretion is inhibited by atropine. Atropine is an anticholinergic drug that competitively inhibits ACh at postganglionic sites, inhibiting parasympathetic activity. Pilocarpine actually stimulates salivation because of its muscarinic action. Cimetidine is an antagonist for the histamine H2 rec...
1
Atropine
Pilocarpine
Cimetidine
Aspirin
Physiology
G.I.T.
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single
While recording the rest position of the mandible, the patient’s head position should be
In this position, action of the muscles that regulate mandibular position is equalized and mandible is free of any undue pull of any muscle.
1
Head should be upright and unsupported
Head should be supported by the head rest
Patient should be lying in repose position
The neck should be extended
Dental
null
155a20af-f9ad-47b1-9b8c-6343c661f969
single
All the following are true about measles vaccine except –
null
4
Given subcutaneously
High efficacy
Given below 1 year of age
Diluent not required
Pediatrics
null
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multi
Occipitomental x ray view of paranasal sinuses with open mouth is Known as
ref : hazarika 4th ed
4
water's view
Caldwell view
Towne's view
Pierre's view
ENT
All India exam
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single
Which of the following is suitably accommodated within the first turn of an alpha helix?
The stability of an alpha helix arises primarily from hydrogen bonds formed between the oxygen of the peptide bond carbonyl and the hydrogen atom of the peptide bond nitrogen of the fouh residue down the polypeptide chain. The ability to form the maximum number of hydrogen bonds, supplemented by van der Waals interacti...
4
Alanine
Aspaic acid
Tyrosine
Glycine
Biochemistry
null
21c54a12-ea0d-4797-8b13-66d5c547194f
single
Knee joint in a patient with Hemophilic ahritis shows all of the following except
Following are the characteristic finding in knee Hemophilic ahritis SUBACUTE OR CHRONIC AHRITIS * Recurrent hemahroses, may lead to a self-perpetuating condition * Joint abnormalities persist in intervals between bleeding episodes * Involved joint is chronically swollen although painless and only slightly warm * Chroni...
3
Juxtraicular osteosclerosis
Squaring of patella
Narrowing of Intercondylar notch
Subchondral cysts
Orthopaedics
Joint disorders
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multi
At physiological pH, carboxy terminal of peptide is
In ion-exchange chromatography, proteins interact with the stationary phase by charge-charge interactions. Proteins with a net positive charge at a given pH will tightly adhere to beads with negatively charged functional groups such as carboxylates or sulfates (cation exchangers).   Harper, Ed 30, Pg 27
2
Positive charged
Negative charged
Neutral
Infinitely charged
Biochemistry
null
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single
Percentage of Halothane metabolized ?
Ans. is 'd' i.e., 20% Most of the inhaled anaesthetics are eliminated from lungu though some metabolism in liver may occur. In terms of extent of hepatic metabolism, the rank of order is methoxyflurane (> 50%) > Halothane (20%) > Ether (10-157o) > enflurane (3-5%) desflurane (< 0.1%) > NrO (0%). NrO does not have any m...
4
1%
5%
10%
20%
Anaesthesia
null
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single
Group of viruses that inhabit the alimentary tract of children below 2 years age:
null
1
Coxsackie virus
Paramyxovirus
Varicella zoster virus
Herpes simplex virus
Medicine
null
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single
Second most common cause of chromosomal abnormality causing mental retardation -
"Fragile X syndrome is the second most common genetic cause of mental retardation, after Down syndrome".
2
Down's syndrome
Fragile X syndrome
Edward syndrome
Patau syndrome
Psychiatry
null
3cb5327a-2fb8-4c54-a113-70f4e8a15e3c
single
Which of the following is not a tumor marker:
Human leucocyte antigen A2 REF: Harper biochemistry 25th edition page 809, (American cancer society) http://www.cancer. org/acs/groups/cid/documents/webcontent/003189-pdf.pdf, http://en.wikipedia.org/wiki/Tumor_antigen, See APPENDIX-26 for list of "Tumor markers" A tumor marker is a substance found in the blood, urine,...
3
CEA
Tyrosinase
Human leucocyte antigen A2
AFP
Pathology
null
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single
Which of the following is the usual presenting symptom of pseudocyst in pancreatitis?
Pseudocysts are caused by pancreatitis in 90% of cases and by trauma in 10%. Approximately 85% are located in the body or tail of the pancreas. Some patients have two or more pseudocysts. Abdominal pain is the usual presenting complaint. Reference: Harrisons Principles of Internal Medicine, 18th Edition, Page 2642
2
Abdominal swelling
Abdominal pain
Persistent vomiting
Early satiety and postprandial fullness
Medicine
null
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single
Which of the following statement regarding Clomiphene citrate is true?
Clomiphene citrate is a racemic mixture of enclomiphene & zuclomiphene. Clomiphene citrate is a triphenylethylene; its two isomers, zuclomiphene (cis-clomiphene) and enclomiphene (trans-clomiphene), are a weak estrogen agonist and a potent antagonist, respectively. The incidence of multiple pregnancies is approximately...
1
Enclomiphene is anti-estrogenic
Increases pregnancy rate 3 times as compared to placebo
Incidence of twin pregnancy is 5-6%
It has been shown to increase feility in oligospermic males in randomized controlled trials
Gynaecology & Obstetrics
null
ad5c88e5-d739-4ae7-aa57-a7d08efb900f
multi
Most common site affected by psoriasis is?
ANSWER: (B) Extensor surfaceREF: Rook's textbook of dermatology 7th e p. 35.1"Most commonly involved areas in psoriasis is Extensor aspect of knees, elbows & Scalp"
2
Flexor surface
Extensor surface
Palms and soles
Oral mucosa
Skin
Psoriasis
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single
Fibrinoid necorsis with neutrophilic infiltration is seen in ?
Ans. is 'a' i.e., PAN
1
PAN
Giant cell aeritis
Takayasu aeritis
Wegener's granulomatosis
Pathology
null
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single
Twelve-year-old boy with vesicle over lip. Investigation to be done is:
Ans. b. Tzanck smearHerpes labialis occurs due to HSV-I injection on Tzanck smear shows, multinucleated giant cells (MNGC).
2
KOH mount
Tzank smear
Diascopy
Woods lamp
Skin
Skin Lesions And Disorders Of Pigmentation
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single
Baker's cyst is
Ans. b (Herniation of synovium of knee joint) (Ref. Maheshwari orthopedics 3rd/pg. 276)Baker's cyst is formed when synovial fluid (fluid that is produced by the joint lining to lubricate and protect the joints) escapes from the knee joint capsule (also called the synovial sac or synovium) and forms a new sac outside th...
2
Semimembranosus bursitis
Herniation of synovium of knee joint in popliteal fossa
Bone cyst arising from femur
Synovial degenerative disease
Orthopaedics
Injuries Around the Thigh & Knee
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single
The major storage and circulatory form of vitamin D is:-
Cholecalciferol is first hydroxylated at 25th position to 25-hydroxycholecalciferol (25-OH o3) bv a specific hydroxylase present in  liver. 25-OH D3 is the major storage and circulatory form of vitamin D. Reference: Satyanarayana- Biochemistry, 3rd edition, pg-125
1
25-hydroxycholecalciferol
1,25-dihydroxycholecalciferol
Cholecalciferol
Calcitriol
Biochemistry
null
ab34a206-b0c6-4474-9937-430aa1d85595
single
Flow rate of unstimulated saliva from the parotid gland is:
null
1
0.4ml/min
0.1ml/min.
0.8ml/min.
1ml/min
Dental
null
ca6b4b2e-956a-48d6-96c3-9546621081d3
single
Bosophillic stippling is seen in
Refer robbins 8/e p406 Lead poisoning is a type of metal poisoningcaused by lead in the body. The brain is the most sensitive. Symptoms may include abdominal pain, constipation, headaches, irritability, memory problems, inability to have children, and tingling in the hands and feet. It causes almost 10% of intellectual...
2
Cadmium Poisoning
Lead Poisoning
Chromium poisoning
Iron poisoning
Anatomy
miscellaneous
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single
Risk of malignancy in BIRADS score 2 is
BIRADS score - Breast Imaging Repoing and Data System Category 2- Negative, routine mammogram in 1 year is recommended
1
0-2%
2-4%
10%
50%
Anatomy
Endocrinology and breast
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single
Rota virus causes -
rota virus is the mos common causevof diatrheal disease in infants&children REF:ANATHANARAYANAN MICROBIOLOGY NINTH EDITION PAGE.561
2
Acute nonbacterial gasteroenteritis in adult
Infantile diarrhea
Teratogenic effects
Respiratory infection in immunocompromised
Microbiology
Virology
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single