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Septic shock is due to -
Septic shock results most often from gram-negative bacteria entering the body. lysis of gram negative bacteria releases endotoxin, a lipopolysaccharide into the circulation. it is responsible for immune system activation and systemic inflammatory response. Reference:rush Mohan textbook of pathology, 7th edition, pg no:...
2
Protein
Lipopolysaccharide
Teichoic acid
Peptidoglycan
Microbiology
Immunology
6b32e1bc-ee66-4920-b3ec-5773130d0c3f
single
Open book and bucket handle injuries are seen in:
B i.e. Pelvis
2
Spine
Pelvis
Femur
Humerus
Surgery
null
d8cacc0e-ff8d-4c2e-940c-c2340d388d36
single
Window period for HIV infection is
null
1
3-12 weeks
8-20 weeks
6-24 weeks
None
Social & Preventive Medicine
null
48783079-5480-482b-87e5-c34a87f03e78
multi
Blue sclera is characteristic of?
ANSWER: (B) Osteogenesis imperfectaREF: Khurana 4th ed page 131, Yanoff 2nd ed page 518BLUE SCLERA:It is an asymptomatic condition characterised by marked, generalised blue discolouration of sclera due to thinning. It is a typical association of osteogenesis imperfecta. Osteogenesis imperfecta is an inherited condition...
2
Amelogenesis Imperfecta
Osteogenesis imperfect
Tetracycline hypoplasia
Fluorosis
Ophthalmology
Miscellaneous (Sclera)
7567402c-bb4e-4caa-8380-495a477ae62b
single
30 year old young male came with sudden onset visual loss with no h/o trauma and the fundus details cant be appreciated with no significant systemic history. The other eye has evidence of sheathing of vessels in periphery. A diagnosis of Eale's disease is made. The most common presenting symptom of this disease is
EALES DISEASE -Bilateral, Idiopathic, Occlusive, Peripheral periphlebitis -also known as angiopathia retinae juvenilis, periphlebitis retinae, primary perivasculitis of the retina. -Recurrent Vitreous Hemorrhage in young and is the most impoant and pathognomic identifying feature -There can be subtle signs of sheathing...
2
Neovascularization
Recurrent vitreous hemorrhage
Macular edema
Posterior subcapsular cataract
Ophthalmology
Vitreous Humour, Uveal Disorders
e531716e-a225-4bda-95f0-0ab6a8b7de42
single
During starvation, brain utilizes -
Ans. is 'c' i.e.. Ketone bodies o There is no stored fuel in brainQ, but it utilized 60% of total energy under resting conditionsQ,o Glucose is virtually the sole fuel for the brainQ, except in prolonged starving when ketone bodies are the major sourceQ.o Fatty acids do not serve as fuel for the brain, because they are...
3
Glycogen
Fattey acids
Ketone bodies
None
Biochemistry
Carbohydrates
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multi
Chocolate Brown postmortem staining is seen in –
In poisoning by nitrites, potassium chlorate, nitrobenzene, potassium bicarbonate and aniline the colour of postmortem hypostasis is chocolate brown due to methemoglobinemia.
3
H S Poisoning
Opium Poisoning
KCl Poisoning
Cyanide poisoning
Forensic Medicine
null
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single
Factors which decrease insensible water losses are all, except –
Prematurity increases insensible water loss.
4
Humidified air
Sedation
Hypothermia
Prematurity
Pediatrics
null
b2d0281d-0d5f-4350-ba18-ac68195c164a
multi
What is the clearance of a substance, if its concentration in plasma is 10 mg%, concentration in urine is 100 mg% and urine flow is 2 ml/min?
Ans. D. 20ml/min.rate of elimination = amount of drug excreted per hour concentration in urine x urine flow 2mg/min = 100 mg% x 2 ml/minNow Cl = RoE/Plasma concentration Therefore, Clearance =2mg/min/10mg%=20ml/min.
4
0.02 ml/min
0.2 ml/min
2 ml/min
20 ml/min
Pharmacology
General Pharmacology
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single
A mutation in the codon which causes a change in the coded amino acid, is known as
Missense mutation causes change in codon so that it codes for a different amino acid.
3
Mitogenesis
Somatic mutation
Missense mutation
Recombination
Biochemistry
null
ac3c8000-230d-4685-b679-0921d608ebd5
single
A 6 year old child is continuously criticized by the teachers in classroom, it is a type of :
null
3
Physical abuse
Failure to thrive
Emotional abuse
Any of the above
Dental
null
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multi
Operation theatres are sterilized by: March 2007
Ans. B: Formaldehyde fumigation Chemical Sterilization Although heating provides the most reliable way to rid objects of all transmissible agents, it is not always appropriate, because it will damage heat-sensitive materials such as biological materials, fiber optics, electronics, and many plastics. Ethylene oxide High...
2
Ethylene oxide gas
Formaldehyde fumigation
Washing with soap water
Carbolic acid spraying
Microbiology
null
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single
Bacterial vegetations in heart valves are seen in:
null
2
Rheumatic heart disease
Infective endocarditis
A-V shunt
Corpulmonale
Medicine
null
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single
Clinical features of hyperprolactinaemia are all except
Hyperprolactinemia is not associated with ambiguous genitalia.
4
Oligomenorrhea
Galactorrhea
Recurrent abortions
Ambiguous genitalia
Gynaecology & Obstetrics
null
3686e9cb-6b66-4b19-9c49-02adcec134e9
multi
All the following signs could result from infection within the right cavernous sinus, except
B i.e. Loss of corneal blink reflex
2
Loss of pupillary light reflex.
Loss of corneal blink reflex.
Ptosis
Right ophthalmopegia
Ophthalmology
null
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multi
HPV type least commonly associated with carcinoma cervix :
HPV High oncongenicity: Types 16,18, 31, 33, 35, 45, 56 Low oncogenecity: Types 6,11, 42, 43 Ref: D.C.DUTTA&;S TEXTBOOK OF GYNAECOLOGY; 6th edition; Pg no:323
1
6
35
16
18
Gynaecology & Obstetrics
Gynaecological oncology
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Ogaura Inawa and Hikojima are the serotypes of:
Ans. is. 'b' i. e., Vibrio cholerae
2
Yersina
Vibrio cholerae
E Coli
Salmonella typhi
Microbiology
null
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single
Secretin does not cause :
D i.e. Gastric secretion increases
4
Secretin does not cause :
Auguments the action of CCK
Contraction of pyloic sphincter
Gastric secretion increase
Physiology
null
d393fbfb-e4de-4899-a9a0-6b848cb2abd7
single
The terminal branches of the external carotid artery are:
null
4
Superficial temporal and transverse facial
Transverse facial and maxillary
Posterior auricular and maxillary
Superficial temporal and maxillary
Anatomy
null
164d2ffc-ef07-4929-a8c8-f3988ff1c30a
single
Which of the following methods is most suitable for isolating gene of long DNA molecules
Chromosome walking is the best method to isolate gene from long segment of DNA.
4
Sanger's sequencing
Southern blotting RFCP
RFCP
Chromosome walking
Biochemistry
null
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single
Which of the following drug can be used for medical adrenalectomy?
DRUGS INHIBITING THE FORMATION OF ADRENAL STEROIDS These drugs can be used for medical adrenalectomy Metyrapone Ketoconazole Aminoglutethimide Mitotane
4
Metyrapone
Ketoconazole
Aminoglutethimide
All of the above
Pharmacology
Adrenal
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multi
In which form of aminoacid is ammonia transported from skeletal muscle to liver?
Ans. is 'c' i.e., Alanine* Two mechanisms are available for transport of ammonia from the peripheral tissues to the liver.1) In the form of glutamine# In many tissues like liver, kidney and brain, ammonia combines with glutamate to yield glutamine, by the action of glutamine synthase. The brain is a rich source of glut...
3
Glutamate
Glutamine
Alanine
Glycine
Biochemistry
Proteins and Amino Acids
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single
The following are true of PKDL except -
Recccurence doesnt depend on full tratment , reccurence is even seen after full treatment. Persistent hypergammaglobulinemia is seen in Kala azar which is detected by antimony test which is done for Kala azar. Cancrum oris can occur in Kala azar. Option 1, 2, 3, 4 PKDL (Post Kala-azar Dermal Leishmaniasis): Seen in 2-1...
4
Persistent hypergammaglobulinemia
Seen in 2-10 year after succesfull treatment of VL
Cancrum oris can occur
Full treatment prevents PKDL
Microbiology
Parasitology Pa 1 (Protozoology)
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multi
IPC which deals with dowry death is -
Ref:Textbook of forensic medicine & toxicology Nageshkumar G Rao 2nd edition pg 594 Sec 304-B IPC Dowry death-- When death of a woman occurs due to burn or other bodily injury or in circumstances other than normal within 7 years of marriage,and it is seen that she was submitted to cruelty or harassment by her husband o...
2
304A
304B
303
302
Forensic Medicine
Special topics
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single
All of the following statements regarding amyloidosis are true except -
Ans. is 'c' i.e., Renal Amyloidosis commonly presents with Hypeension Most common presentation is proteinuria. o Hypeension may occur but it is not common, it occurs in 20-50% of the patients. "Although earlier it was thought that hypeension was an infrequent complication, more recently up to 50% of patients have been ...
3
Multiple myeloma - shows AL type deposits
Secondary amyloidosis - shows AA type deposits
Renal amyloidosis - shows AA type deposits
Renal amyloidosis commonly presents with mild proteinuria
Pathology
null
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multi
Sunderland classification is used for ?
Ans. is 'a' i.e., Nerve injury Sunderland is an extension of the seddon classification and includes 5 types of nerve injuries.
1
Nerve injury
Muscle injury
Tendon injury
Ligament injury
Surgery
null
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single
In pyridoxine deficiency, tryptophan is converted to -
Ans. is 'c' i.e., Xantheurenic acid o In vitamin B6 deficiency the metabolism is shuted to xanthurenic acid. Therefore, xantheurenic acid excretion is increased in urine.
3
Nicotine
Acetoacetate
Xantheurenic acid
Acetyl CoA
Biochemistry
Amino Acid Metabolism
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single
Focal and diffuse thickening of gallbladder wall with high amplitude reflections and 'comet tail' artifacts on USG suggest the diagnosis of –
Focal and diffuse thickening of gallbladder wall with comet tail artifact is characteristic of adenomyomatosis of the gallbladder.
3
Xanthogranulomatous cholecysitis
Carcinoma of gall bladder
Adenomyomatosis
Cholesterolosis
Radiology
null
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multi
All of the following lower intracranial pressure except-
Following steps are used to lower intracranial pressure Ventrititlostomy to drain CSF Elevate head end of bed Osmotherapy -- mannitol, hypeonic saline Glucocoiciods dexamethasone for vasogenic edema from tumor, abscess (avoid glucocoicoids in head trauma, ischemic and hemorrhagic stroke) Sedation (morphine, propofol, o...
2
Mannitol
Furosemide
Coicosteroids
Hyperventilation
Surgery
Head and neck
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multi
Maximum refractive index ?
Ans. is 'c' i.e., Lens Lens has maximum refractive index among the refractive structures of eye. The refractive indices of the successive layers of lens increase from the periphery towards the nucleus.
3
Cornea
Air
Lens
Vitreous
Ophthalmology
null
34e76f70-c18d-4d13-90a8-a0de6e0ed8cc
single
Cholemicnephrosis seen in ?
Ans. is 'd' i.e., Obstructive jaundiceCholemicNephrosis 'Jaundice related Neuhropathyl Cholemicnephrosis is used to describe the renal failure in patients with obstructive jaundice, paicularly after renal transplantation.Diagnosis is made on light microscopy by presence of typical bilirubin casts.Altered hemodynamics a...
4
Addison's disease
Hemochromatosis
Hemochromatosis
Obstructive jaundice
Pathology
null
842ffd3e-be3f-4e88-8ea1-7e2bc98288e9
single
A 52-year-old man presents to the out-patient clinic complaining of episodes of severe unilateral, stabbing facial pain that is intermittent for several hours, and then disappears for several days. The pain is described as "electric shock-like" and only lasts a few seconds. Physical examination of the face and mouth is...
This patient has trigeminal neuralgia. Carbamazepine (an anticonvulsant drug) is given in doses varying from 600 to 1200 mg/day. Phenytoin has also been used. The two drugs can also be used in combination. Operative procedures include alcohol injection of the nerve or ganglion, partial section of the nerve in the middl...
4
morphine
indomethacin
cimetidine
carbamazepine
Medicine
C.N.S.
62d8f9b3-a99b-42d0-a0b4-e6883005bcb0
single
Which of the following represents Weber Fechner Law?
The intensity of sensation is determined by the amplitude of the stimulus applied to the receptor. Action potentials in an afferent fiber from a mechanoreceptor of a single sensory unit increase in frequency as branches of the afferent neuron are stimulated by pressure of increasing magnitude. The magnitude of sensatio...
1
Magnitude of stimulus strength perceived is approximately propoionate to the log of the intensity of stimulus strength
Magnitude of stimulus strength perceived is directly propoional to the intensity of stimulus strength
Threshold of receptor is directly propoional to stimulus strength
Threshold of receptor is inversely propoional to stimulus strength
Physiology
null
f7a56653-0b1e-4001-9cb7-7de0a3c5307b
single
Toxicity of AH26 sealer is due release of
null
1
Formaldehyde
Eugenol
Resin acid
Gluteraldehyde
Dental
null
b8c7f2fd-05f1-4824-be32-0d6226487155
single
Thorium induced tumor is which of the following?
Angiosarcoma of the liver is a highly aggressive tumor which is associated with exposure to: Vinyl chloride Arsenic Thorotrast Thorotrast is a suspension containing paicles of the radioactive compound thorium dioxide. It emits alpha paicles due to which it has been found to be extremely carcinogenic.
3
Renal cell carcinoma
Lymphoma
Angiosarcoma of liver
Astrocytoma
Pathology
Etiological Factors of Neoplasia
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single
Toxin involved in the streptococcal toxic shock syndrome is -a) Pyrogenic toxinb) Erythrogenic toxinc) Hemolysind) Neurotoxin
null
3
ac
a
ab
bc
Microbiology
null
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single
All findings are seen in a patient with isolated aoic stenosis except?
Aoic stenosis(AS) Results in LVH -Double apical impulse and shift of apex beat laterally. Characteristic pulse -Pulsus parvus et tardus. Early stages -BP -Normal. Later stages -Low SBP , | Pulse pressure. Murmur - Ejection systolic murmur with carotid thrill. Pulsus bisferiens is seen in HOCM & severe AR.
2
Left ventricular impulse is displaced laterally
Pulsus bisferiens is hallmark finding
Systemic BP is normal in early stages of disease
Carotid thrill
Medicine
Valvular hea diseases
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multi
Fatal dose of methanol -
Fatal dose of methyl alcohol is 60-250 ml in adults, but as little is 15 ml can cause blindness.
3
15 ml
30-60 ml
60-250 ml
500 ml
Forensic Medicine
null
a71cd4dd-9890-4431-8bbb-dc9a122f3ac7
single
A herd immunity of over .........is considered necessary to prevent epidemic spread of diphtheria:
70%
4
50%
55%
60%
70%
Social & Preventive Medicine
null
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single
In case of PSGN complication commonly seen are all Except
PSGN complications are -Acute renal failureChronic glomerulonephritisChronic renal diseaseCongestive hea failure or pulmonary oedemaEnd-stage renal diseaseHyperkalemiaHigh blood pressure (hypeension)Nephritic syndrome
4
LVF
Hypeensive encephalopathy
Hyperkalemia
Bleeding diathesis
Microbiology
All India exam
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multi
A 52-year-old man was referred to the clinic due to increased abdominal girth. He is diagnosed with ascites by the presence of a fluid thrill and shifting dullness on percussion. After administering diuretic therapy, which nursing action would be most effective in ensuring safe care?
For the client with ascites receiving diuretic therapy, careful intake and output measurement are essential for safe diuretic therapy. Diuretics lead to fluid losses, which if not monitored closely and documented, could place the client at risk for serious fluid and electrolyte imbalances. Hypokalemia, not hyperkalem...
4
Measuring serum potassium for hyperkalemia
Assessing the client for hypervolemia
Measuring the client’s weight weekly
Documenting precise intake and output
Medicine
null
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single
Differentiating feature of female pelvis is -a) Subpubic angle V shapedb) Subpubic angle U shaped and obtusec) Pre auricular sulcus is prominentd) Ischial tuberosity is everted and obturator foramen is large and ovale) Ischial tuberosity is everted and obturator foramen small and triangular
Subpubic angle in females is U shaped, rounded and obtuse (90-100o). Preauricular sulcus is more frequent, broad and deep in female pelvis. In female pelvis, ischial tuberosity is everted and obturator foramen is small triangular.
1
bce
bc
acd
ace
Forensic Medicine
null
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multi
A 30 year old known SLE female presents with ankle swelling. Her BP is 170/100 mmHg and she has marked lower limb edema. Urine dip stick discloses 4+ proteins with no hematuria. Plasma creatinine is 1.4 mg/dl, albumin is 1.5 g/dl and urine protein excretion rate was 6 gms for 24 hours. What is the cause of this present...
null
3
Amyloidosis
Class II lupus nephritis
Class V lupus nephritis
Pericardial effusion
Medicine
null
30739838-aeea-4eee-9dbe-b3b6f0be5485
single
Pus formation in lacerated wound occurs in:
Normally, pus formation occurs in about 48 hours, but in a lacerated wound it occurs slightly earlier.
2
12-24 hours
24-48 hours
48-72 hours
1 week
Surgery
null
c46d53f6-c4a9-4579-8963-1acc2992f861
single
The best investigation for colorectal carcinoma:
Ans: d (Colonoscopy and biopsy)Ref: Bailey & Love, 24,hed, p. 1179 & 23rd ed,p.1051
4
Exfoliative cytology
Air contrast barium enema
Ultrasound
Colonoscopy and biopsy
Surgery
Small & Large Intestine
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single
Treatment of choice for hairy cell leukaemia is
The first-line therapy for hairy cell leukemia is cladribine, 0.1 mg/kg/d by continuous intravenous infusion for 7 days. The drug can be administered on an outpatient basis with a pump, after placement of a percutaneous intravenous central catheter (PICC). Ref Harrison 20th edition pg 544
2
Steroids
Cladribine
Splenectomy
Pentostatin
Medicine
Oncology
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A 23 year old asymptomatic woman attends her family physician for thyroid function testing as her mother has recently been commenced on levothyroxine. Thyroid functiontests (TFTs) show TSH 6miU/L, and free T4 of 12.4 pmoi/L (0.96 ng/dL). Her serum thyroid peroxidase antibodies are strongly positive. What is the most ap...
This woman has subclinical hypothyroidism. There is no benefit in checking thyroglobulin antibodies as it does not change her diagnosis or management. With positive thyroid peroxidase antibodies she has a higher risk of progression to overt thyroid failure. A trial of thyroxine replacement would be advocated if her TSH...
2
Check thyroglobulin antibodies
Arrange a scintigraphy scan
Reassure and discharge
Repeat TFT s in 4-6 months
Medicine
null
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single
Twenty-four hours following paial thyroidectomy where the inferior thyroid aery was also ligated (tied off), the patient now spoke with a hoarse voice (whisper), and had difficulty in breathing. Which nerve was injured?
The recurrent laryngeal nerve runs with the inferior thyroid aery toward the lower lobes of the thyroid, This means that the recurrent laryngeal nerve would be at risk in any surgery involving the inferior thyroid aery or the inferior poles of the thyroid. The recurrent laryngeal nerve becomes the inferior laryngeal ne...
4
Internal branch of superior laryngeal
Ansa cervicalis
Ansa subcla
Recurrent laryngeal
ENT
null
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single
Which of the following is true about pasteurization?
Ans. is 'b' i.e., It kills all bacteria except thermoduric bacteria (Ref: Ananthanarayan, 9th/e, p. 31, 8th/e, p. 31-32) Thermoduric bacteria - Bacteria which can survive, to varying extents, the pasteurization process.Pasteurization kills nearly 90% of bacteria in milk except certain bacteria like Coxiella burnetti wh...
2
It kills all bacteria and spores
It kills all bacteria except thermoduric bacteria
It kills 95% of microorganisms
All bacteria are destroyed
Microbiology
General
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multi
Destruction of which nucleus results in starvation?
Lateral nucleus Stimulation induces eating.  Destruction results in starvation.
1
Lateral nucleus
Arcuate nucleus
Posterior nucleus
Suprachiasmatic nucleus
Physiology
null
5da69a75-e2cc-42dd-8dc4-3c2635d9e639
single
Pre conceptional intake of which of the following will decrease the incidence of neural tube defects?
Prophylactic folic acid supplementation in  2nd and 3rd  trimester along with Vit. K in the last month of pregnancy is recommended, particularly in women receiving antiepileptic drugs to minimise neural tube defects and bleeding disorder respectively in the neonate. Reference: Essentials of Medical Pharmacology Eighth ...
1
Folate
Vitamin E
Vitamin C
All of the above
Pharmacology
null
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multi
Chylothorax is common on right side because
Chylothorax is common on right side because of long course of thoracic duct towards right side.
1
Long course of thoracic duct towards right side
Presence of Liver on right side
Right lung has 3 lobes in contrast to left having 2 lobes
Due to megalymphatic congenital anomaly on right side
Surgery
null
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single
Essential granulation tissue constituents include all except
null
3
Fibroblast
Macrophages
Polymorphs
Budding blood vessels
Pathology
null
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multi
"Poers of Infection" are -
Houseflies are commonest and familiar insects which live close to man. House flies are exceptionally efficient mechanical spreaders of disease. They transpo microorganisms on their feet and hairy leg. Pathogenic organisms, ova, and cysts have been recovered from bodies of the housefly. House flies are called 'poers of ...
2
Anopheles
Housefly
Aedes
Cockroaches
Social & Preventive Medicine
Environment and health
8830d115-683b-4762-a049-408a692145ec
single
All of the following statements regarding ductus deference are true except
The ductus deferens is the continuation of the tail of the epididymis and runs in the spermatic cord through the scrotum, inguinal canal and into the abdominal cavity, where it is extra-peritoneal. There it travels laterally through the pelvis, passing anterior to the ureter and inferior to the bladder, where it unites...
4
The terminal pa is dilated to form ampulla
It crosses ureter in the region of ischial spine
It passes lateral to inferior epigastric aery at deep inguinal ring
It is separated from the base of bladder by the peritoneum
Anatomy
Abdomen and pelvis
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multi
All of the following are adverse effects of Digoxin except
Digoxin can cause all type of arryhthmias except Atrial Flutter. Infact Digoxin is used to treat Atrial Flutter.
3
Hyperkalemia
Yellow vision
Atrial Flutter
Gynaecomastia
Pharmacology
null
dc529891-06c3-455c-8a00-a62521008c0b
multi
An essential amino acid in man is
Isoleucine, Leucine, Threonine, Lysine, Methionine, Phenylalanine, Tryptophan, and Valine are essential amino acids. Reference: Vasudevan 7th  ed, pg 27
3
Aspartate
Tyrosine
Methionine
Serine
Biochemistry
null
42f8ee19-b674-42b0-8c71-253299cec405
single
Inner ear fully developed at
Ans. is 'c' i.e., 20 weeksDevelopment of membranous internal ear is completed by 10" weeks and reaches its adult size and shape by 20-22 weeks when the cochlea is developed sufficiently.
3
4 weeks
10 weeks
20 weeks
32 weeks
Anatomy
null
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single
Which one of the following increases intracranial tension
(B) Ketamine
2
Thiopentone
Ketamine
Halothane
Propofol
Anaesthesia
Miscellaneous
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single
If VDO is increased all will happen except:
null
1
Perleche
Improper aesthetics
Trauma to TMJ
Trauma to muscles
Dental
null
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multi
Retinitis pigmentosa is associated with all of the following syndromes, EXCEPT:
The many and diverse syndromes to which retinitis pigmentosa may be linked include the following: Oligophrenia, obesity, syndactyly, and hypogonadism (Bardet-Biedl syndrome); hypogenitalism, obesity, and mental deficiency (Laurence-Moon syndrome); Friedreich and other types of spinocerebellar and cerebellar ataxia; spa...
4
Usher's syndrome
Bassen-Kornzweig disease
Kearns-Sayre syndromes
Marfan syndrome
Ophthalmology
null
9a737df5-008c-46b1-bc4f-b5089ebfc39e
multi
In cold caloric stimulation test, the cold water induces movement of the eyeball in the following direction
When Ice cold or warm water or air is irrigated into the external auditory canal, the temperature difference between the body and the injected water creates a convective current in the endolymph of the nearby horizontal semicircular canal. If the water is cold relative to the body temperature (30degC or below), the end...
1
Towards the opposite side
Towards the same side
Upwards
Downwards
ENT
Ear
b41ddb1e-ee7d-46e7-a55d-b9728b22f23d
multi
Functional residual capacity is:
C i.e. Volume remaining after normal expiration
3
Volume remaining after forced expiration
Tidal volume + volume inspired forcefully
Volume remaining after normal expiration
Tidal volume + volume expired by forced expiration
Physiology
null
c9cdc713-f7ff-42d6-b4f3-ddb3d651e910
single
All cause diarrhea except;
Hypercalcemia increases the tone of sphincters of the gut leading to refractory constipation. Autonomic dysfunction in diabetes explains the diarrhea. Due to sympathetic activity increase in thyrotoxicosis there is a reduction in small bowel transit time explaining the diarrhea. IBS has variable presentation between di...
2
Diabetes
Hypercalcemia
Hypehyroidism
Irritable bowel syndrome
Medicine
Malabsorbtion Syndrome
dbaea293-b4a9-499f-9fda-43b83a8481ca
multi
Gaze fixation takes place at which age
Gaze fixation stas developing in the first month and is completed in 6 months The macula is fully developed by 4-6 months Fusional reflexes, stereopsis, and accommodation is well developed by 4-6 months Cornea attains normal adult diameter by 2 years of age Lens grows throughout life. Reference : AK Khurana Comprehensi...
2
3 months
6 months
1 year
2 years
Ophthalmology
Anatomy, Development and clinical examination
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single
All of the following statements about the periosteum are true except?
The periosteum is highly sensitive to pain. Note that the needle touching the periosteum in inadvertent intramuscular injection can produce severe pain.
4
It is highly vascular
It does not cover the articular surface of the bones
It is pierced by the fibres of sharply
It is insensitive to pain
Anatomy
null
357e8cb5-24b5-4445-8c93-0a2a554210fb
multi
Aldosterone receptors are present in all except
The mineralocoicoid receptor (or MR, MLR, MCR), also known as the aldosterone receptor or nuclear receptor subfamily 3, is a receptor with equal affinity for mineralocoicoids and glucocoicoids.mineralocoicoid receptor is expressed in many tissues, such as the kidney, colon, hea, central nervous system (hippocampus), br...
1
Liver
Colon
Hippocampus
Distal nephron
Physiology
Endocrinology
70e4345a-04f3-4d80-b426-44bcc511ce63
multi
Which of the following does not directly drain into right atrium ?
Great cardiac veinGreat cardiac vein does not directly drains into right atrium. It drains into coronary sinus, which in turn drains into right atrium.Veinous drainage of heaCoronary sinus : Opens into right atrium and has following tributries : (i) Great cardiac vein, (ii) Middle cardiac vein, (iii) Posterior vein of ...
1
Great cardiac vein
Anterior cardiac vein
Thebasian vein
Venae cordis minimi
Anatomy
null
48ac8893-b8b0-4aa6-bed3-6463f32c13bd
single
Most common site of metastasis in lung carcinoma:
Metastasis- M/c site of metastasis in CA lung is brain (new updates)- B>B>L>A>L* Brain > Bone > Liver > Adrenal > lung
4
Liver
Adrenal
Bone
Brain
Surgery
Oncology
8d3134eb-b48f-4f08-aab0-938cac7222eb
single
A 10 month old male patient comes with vomiting, lethargy and severe jaundice when weaning was started with fruit juice. Laboratory diagnosis reveals prolonged clotting time, hypoalbuminemia, elevation of bilirubin and transaminase levels. Which of the following enzyme is defective?
Hereditary fructose intolerance Autosomal Recessive. Biochemical defect Deficiency of fructose – 1,6 – bisphosphate Aldolase (Aldolase B). The gene for aldolase B is on chromosome 9q22.3. Deficiency of this enzyme activity causes a rapid accumulation of fructose-1-phosphate and initiates severe toxic symptoms when exp...
2
Aldolase A
Aldolase B
Fructokinase
Sucrase
Biochemistry
null
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single
158 Thyroid storm during surgery is most commonly due to ?
null
3
Perioperative intervention
Glucocorticoid side effect
Inadequate preoperative preparation
Rough handling during surgery
Surgery
null
67469656-f14d-4434-8742-0d25ae323b40
single
A 2 years male boy presenting with sudden severe dyspnoea, most common cause is -
null
1
Foreign body
Bronchiolitis
Asthmatic Attack
None
ENT
null
046a2478-8abb-41a6-87bd-158452a3fa43
multi
Visual center is present in-
Ans. is 'b' i.e., Occipital lobe * Occipital lobe has the following areas related to visioni) Primary visual cortex (strike area, area 17) : It is present in medial surface of occipital lobe on upper lip and lower lip of calcarine sulcus.ii) Visual association areas (secondary visual area, areas 18, 19) : It include pa...
2
Parietal lobe
Occipital lobe
Frontal lobe
Temporal Lobe
Anatomy
Neuroanatomy
e2d8129d-921d-4c7c-a597-61adce2431bf
single
To create a poo-caval shunt in a patient with poal hypeension, which of the following venous anastomosis should be performed?
Poacaval shunting is major surgery. It involves a large cut (incision) in the belly area (abdomen). The surgeon then makes a connection between the poal vein (which supplies most of the liver's blood) and the inferior vena cava (the vein that drains blood from most of the lower pa of the body.)The new connection dives ...
4
Superior mesenteric vein to inferior mesenteric vein
Right gastric vein to left gastric vein
Right gastric vein to right gastric vein
Left splenic vein to left renal vein
Anatomy
Abdomen and pelvis
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single
A middle aged female has flaccid bullae in the skin and oral erosion. Histopathology shows intraepidermal acanthololytic blisters. The most likely diagnosis is –
Clues given are :- Flaccid bullae Oral erosion (mucosal involvement) Intraepidermal acantholysis Diagnosis is pemphigus vulgaris.
1
Pemphigus vulgaris
Paraneoplastic pemphigus
Bullous pemphigoid
Dermatitis hepatiformis
Dental
null
f0bf9ac8-f0f1-4c6d-a7fe-5e45239c30b1
single
A metastatic carcinoma in the brain of an adult most often comes from a primary in the -
answer: D
4
Stomach
Ovary
Oral cavity
Lung
Unknown
null
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single
A patient with microcytic hypochromic anemia, Hb-9%, serum iron is 20 p./d1, ferritin level 800 mg/ml, transferrin percentage saturation is 64. What is possible diagnosis aEUR'
Atransferinemia Derangment in serum iron indices mentioned in the question : ? Microcytic hypochromic anemia Low serum iron - Normal (50-170 ,ug/dI) High serum. ferritin Normal (30-400 ng/ml) High serum transferrin Normal (30-50%) Let's look at the options first Iron deficiency anemia Can be easily ruled out as serum f...
1
Atransferrinemia
Iron deficiency anemia
DMT 1 mutation
Hemochromatosis
Pathology
null
a81c722c-e23f-4cfc-940f-0fa5e05409ee
single
Dermatophytes are
Ans: (b) Trichophyton rubrumRef: Harrison 17th ed. /1309DERMATOPHYTOSIS OR RING WORM (TINEA) INFECTION* Dermatophytes include a group of fungi (ring worm) that under most conditions have the ability to infect & survive only on dead keratin; that is the superficial topmost layer of skin (stratum corneum or keratin layer...
2
Tinea versicolor
Trichophyton rubrum
Sporothrix
All of the above
Skin
General
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multi
Range of kuppu swami scale for upper middle class:
Ans. (b) 16-25Ref: K. Park 23rd ed. / 690MODIFIED KUPPUSWAMI SCALE: Scale of socio- economic status of urban families, includes Education status of head, occupation status of head, Income per capita.Total score of 3 componentsSocioeconomic class* 26-29* 16-25* 11-15* 05-10* 03-04UpperUpper-middleLower-middleUpper-lower...
2
26-29
16-25
16-26
26-30
Social & Preventive Medicine
Demography
4d3b9a0e-f8b2-47c1-9d97-9cf697b8e905
single
The first permanent tooth to erupt in the oral cavity is the:
null
2
Mandibular central incisor
Mandibular first molar
Maxillary central incisor
Maxillary first molar
Dental
null
45104496-0b50-4c03-9275-1ce034128e2c
single
Characteristic of type-II respiratory failure is: September 2010
Ans. D: Low PaO2 and high PaCO2 Type II Respiratory Failure (Ventilatory Failure: Aerial Hypercapnia): Paial pressure of CO2 in the aerial blood reflects the efficiency of ventilatory mechanism that clears (washes out) CO2 produced during tissue metabolism. Type II failure can be caused by any disorder that decreases c...
4
Low PaO2 and low PaCO2
Low PaO2 and normal PaCO2
Normal PaO2 and high PaCO2
Low PaO2 and high PaCO2
Medicine
null
19cc43e1-c332-4b45-b0a0-0f7c1c5726e0
single
As per our National Population Policy 2000, the long-term objective is to achive the population stability by which one of the following years?
National population policy 2000 The National Socio-Demographic Goals to be achieved by the year 2010 were as follows: (1) Address the unmet needs for basic reproductive and child health services, supplies and infrastructure. (2) Make school education upto the age 14 free and compulsory, and reduce drop-outs at primary ...
3
2025
2035
2045
2055
Social & Preventive Medicine
Non communicable diseases
07546120-8aba-482d-b1bb-9055c8cbd65d
single
which of the following is a absolute contra indication for ECT
HISTORY * Medunna ====IM injection of camphor to induce seizures * Ugo cerletti and lucio bini==== ECT in a catatonic patient INDICATIONS * DEPRESSION SUICIDAL IDEAS-------------- first choice * CATATONIC SCHIZOPHRENIA * SCHIZOPHRENIA * MANIA * ELECTRODE PLACEMENT * Most commonly used=== bi fronto temporal * More cogni...
4
pediatric
pregnacy
geriatric
nil
Anatomy
Treatment in psychiatry
af6499ea-b612-4431-ab87-4cfea40127e2
single
For fetal lung maturation, all the corticosteroids can be used except:
DOC for fetal lung maturation is betamethasone. Methylprodnisolone is not effective because of poor placental transfer.
4
Betamethasone
Dexamethasone
Hydrocortisone
Methylprednisolone
Gynaecology & Obstetrics
null
a5766730-5d78-4ec5-9c24-0ddb0e7acd2e
multi
Which of the following statements comparing serotonin-dopamine antagonists (SDAs) with dopamine receptor antagonists (DRAs) is true?
Ans. D. SDAs affect both serotonin and glutamate receptorsThe serotonin-dopamine antagonists (SDAs) affect both serotonin and glutamate receptors. However, the SDAs produce minimal or no extrapyramidal symptoms and interact with different subtypes of dopamine receptors than do the standard antipsychotics. They also pro...
4
DRAs is first choice of treatment for schizophrenia.
SDAs produce more neurological adverse effects.
SDAs produce more extrapyramidal symptoms.
SDAs affect both serotonin and glutamate receptors.
Psychiatry
Pharmacotherapy In Psychiatry
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multi
A 62-year-old man reports early satiety, fatigue, and generally feeling unwell. On examination he has a large spleen, appears pale, and the rest of the examination is normal. His blood count is abnormal; the WBC is 50,000/mL with increased mature granulocytes, hemoglobin 9.5 g/dL, and platelets 450,000/mL. Which of the...
This is a case of chronic myelogenous leukemia. The reciprocal translocation involves the long arms of 22 and 9, and results in translocation of the ABL proto-oncogene from chromosome 9 adjacent to a portion of the BCR gene on chromosome 22. The resultant abnormal chromosome 22 is known as the Philadelphia (Phi) chromo...
2
deletion of chromosome 14
reciprocal translocation of 9 and 22 (Philadelphia chromosome)
translocation of the renal artery stenosis (RAS) oncogene
trisomy 21
Medicine
Blood
820e866c-b4d1-473a-9db4-b2db989ba55f
multi
Characteristic feature of cells of collecting duct are
Features of collecting duct cells : No brush border No carbonic anhydrase in lumimal membrane Has 'tight' tight junction Para cellular transport not possible
4
Pressure of brush border
Pressure of carbonic anhydrase in lumimal membrane
It has leaky tight junction
Para cellular transport not possible
Physiology
null
f7cc3b7e-dc74-4ed7-8b7e-c5cc9d0510db
single
which organ is preserved in strychinine poisoning ?
hea : strychinine , digoxin Skin- Hypodermic injections, snake bite, Corrosives. Hair, Nails- Heavy Metal Poisoning. Spinal Cord- Strychnine Poisoning CSF- Alcohol intoxication (in 1.0 mg NaF/ml of fluid) Urine- Narcotics Body Fat- Endrin , DDT(Organo Chlorines). Muscle- When internal organs are badly putrefied. ref : ...
1
hea
brain
liver
csf
Forensic Medicine
All India exam
7aafab3b-e656-4d2e-995e-569b99171086
single
Shift of HCO3– out of RBC in exchange for Cl– is known as
CO2 diffuses through tissue to enter plasma ↓ Inside RBC, CO2 rects with H2O to form Carbonic acid (H2CO3) ↓ H2CO3 Splits to form H+ and HCO3– with the help of enzyme Carbonic anhydrase.
2
Bohr effect
Hamberger shift
Haldane shift
Ondine's shift
Physiology
null
56c65fb2-6004-4278-a843-a2852a7a0d08
single
Which of the following porphyrias is not inherited as an Autosomal Dominant disorder -
Porphyrins are normal pigment present in haemoglobin, myoglobin and cytochrome. Porphyria refers to an uncommon disorder of inborn abnormality of porphyrin metabolism. It results from a genetic deficiency of one of the enzymes required for the synthesis of haem, resulting in excessive production of porphyrins. Often, t...
2
Acute Intermittent Porphyria
Congenital Erythropoietic Porphyria
Porphyria Cutanea Tarda
Hereditary Coproporphyria
Pathology
miscellaneous
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single
Absence of Corpus callosum leads to
Agenesis of corpus callosum is a rare bih defect (congenital disorder) in which there is complete or paial absence of corpus callosum. Corpus callosum is a band of tissue connecting the two hemispheres of the brain. Fibres of corpus callosum arise from the superficial layers of the cerebral coex and they project to the...
4
Hemiparesis
Hemisensory loss
Astereognosis
No neurological manifestations
Medicine
All India exam
9390626a-6457-402f-bd80-c940b04fbd99
multi
Tuberculin test is -
Ans. is 'b' i.e., Intradermal o In tuberculin test, injection is given intradermally on flexor (ventral) surface of left forearm, mid-wav between elbow & wrist.Intradermal injection of PPDon flexor aspect of forearm | Examined at 48-72 hours |||Induration > 10 mmInduration < 5 mmInduration 6-9 mm|||PositiveNegativeEqui...
2
Subcutaneous
Intradermal
Intramuscular
Subdermal
Social & Preventive Medicine
Tuberculosis
694f8980-3d23-48ec-adae-67d6924f38c1
single
Baby with fused eyes and single nasal chamber, undeveloped callosum. What is diagnosis?
A i.e. HoloprosencephalyRef: Nelson, Textbook of Pediatrics, 20th edition, page 2640Explanation:HoloprosencephalyDisorder of neuronal migration with defective cleavage of the prosencephalon (the forebrain of the embryo fails to develop into two hemispheres) and inadequate induction of the forebrain structures.Cause - M...
1
Holoprosencephaly
Schizencephaly
Plagiocephaly
Brachycephaly
Pediatrics
Central Nervous System
79ec7a4d-c8e2-4f5a-894c-fde7bda8dc76
multi
Selective 5–HT4 agonist useful in gastroesophageal reflux disease and lacking arrhythmogenic property is :
Both cisapride and tegaserod are selective 5HT4 agonists useful in the treatment of GERD. Cisapride possesses cardiac K+ channel blocking activity and can lead to torsades de pointes. Tegaserod is devoid of this adverse effect. However, tegaserod has recently been withdrawn due to an increased risk of MI and stroke.
4
Buspirone
Sumatriptan
Cisapride
Tegaserod
Pharmacology
null
9d764167-17f3-47b2-abfa-c511cc7f7e9a
single
All are true about facial recess except:
null
2
Supra pyramical recess
Medially it is bounded by chorda tympani and laterally by facial nerve
Impoant in cochlear implant
Middle ear can be approached through it
ENT
null
ebc90d64-b46f-433c-9809-ac6b671b564a
multi
TRUE about mycoplasma is -
null
1
Causes lung infection
Penicillin is drug of choice
Thick cell wall
Thallium acetate inhibits the growth
Microbiology
null
d77b863d-a11a-477e-80eb-166df2946662
multi
Which is the precursor amino acid for selenocysteine
null
3
Cysteine
Cystine
Serine
Glycine
Biochemistry
null
72c94876-d0a9-4d0a-80e0-915c4cf0d288
single
Risk of Pneumococcal meningitis is seen in :
Ans. is 'a' i.e. Post Splenectomy Patient In table 138-1 p 884 a list of conditions commonly predisposing to pneumococcal infection is given.The list is very long and its not possible to memorize it so I will pick out some important ones for you.Conditions predisposing to pneumococcal infectionsLymphomaMultiple myeloma...
1
Post splenectomy Patient
Patient undergone neurosurgical intervention
Patient following cardiac surgery
Patient with hypoplasia of lung
Microbiology
Bacteria
31bac2b0-bc21-4e7e-bf70-ca0a2ae8a051
single
Following is the advantage of anastrazole over tamoxifen in cases of breast carcinoma -
Ans. is 'c' i.e., Prevents estrogen production from extraovarian sources o Both the drugs anastrazole and tamoxifene are used in the medical management of patients with breast carcinoma. These patients mostly belong to old age group and the main source of estrogen is from peripheral conversion of androgen to estrogen u...
3
Not a teratogen
Causes more cardiomegaly
Prevents estrogen production from extraovarian sources
All of the above
Gynaecology & Obstetrics
Pharmacology in Gynaecology
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multi
Most common location of lymphoma in the G.I.T?
Ans. (a) Stomach* Primary gastric lymphoma is an uncommon condition, accounting for less than 15% of gastric malignancies and about 2% of all lymphomas. However, the stomach is a very common extranodal site for lymphomas (lymphomas originating somewhere else with metastasis to stomach).It is also the most common source...
1
Stomach
Ileum
Mesentery
Colon
Surgery
Benign Gastric Disease
e3e4b228-600e-468d-80fb-e900900cedcd
single